Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ABCA9 EST640918 ENSG00000154258 "ATP binding cassette subfamily A member 9" Q8IUA7 17 68974488-69060949 "Predicted membrane proteins, Transporters" Transport Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 55.5;Fibroblasts: 86.6;Inhibitory neurons: 73.2;Leydig cells: 96.3;Microglial cells: 227.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "ASC diff: 21.8;ASC TERT1: 47.7;HSkMC: 17.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052113, HPA054823" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA052113: AB_2732573, HPA054823: AB_2682615" "unprognostic (3.88e-2)" "unprognostic (9.86e-2)" "unprognostic (2.21e-1)" "unprognostic (9.75e-2)" "unprognostic (4.46e-1)" "unprognostic (5.64e-3)" "unprognostic (4.51e-4)" "unprognostic (1.83e-2)" "unprognostic (1.94e-3)" "unprognostic (7.86e-2)" "unprognostic (3.26e-3)" "unprognostic (3.51e-1)" "unprognostic (7.77e-6)" "unprognostic (5.32e-4)" "unprognostic (7.22e-2)" "unprognostic (1.84e-2)" "unprognostic (4.96e-3)" 33.7 4.1 2.8 1.4 5.1 1.8 22.3 7.7 8.0 14.7 6.3 12.4 1.8 11.2 8.9 4.8 20.6 8.2 22.6 3.0 1.4 2.7 11.9 8.8 2.3 3.1 1.2 27.4 3.5 2.3 4.9 1.2 4.5 3.3 4.0 8.4 9.0 2.8 13.1 9.2 6.6 6.6 1.2 1.6 7.8 5.2 3.5 2.5 11.1 10.6 1.1 10.9 12.7 7.7 0.2 0.4 0.8 0.8 21.8 47.7 0.6 0.4 0.4 0.0 0.4 0.5 0.5 0.6 0.2 0.8 0.3 0.5 0.4 0.7 0.2 0.3 0.4 0.6 2.4 0.6 2.3 0.9 1.3 17.0 0.5 3.6 0.3 0.9 4.8 0.6 0.8 1.3 0.1 0.3 0.3 2.1 0.3 0.2 0.4 2.2 0.1 0.3 0.3 1.9 0.7 0.6 0.5 0.3 0.3 0.4 0.4 0.8 2.0 1.3 0.5 2.3 0.5 1.0 0.5 0.4 0.4 0.5 2.4 0.5 0.1 0.2 0.2 0.1 0.2 0.2 0.1 0.0 0.1 0.2 0.2 0.2 0.4 0.2 0.0 0.1 0.0 0.0 2.8 5.1 7.7 8.0 3.0 1.4 3.1 1.2 4.5 1.2 3.5 7.7 7.4 0.0 1.5 2.6 0.5 1.8 0.3 0.1 1.2 3.9 0.7 0.8 3.9 1.5 0.1 0.0 0.0 0.0 0.6 0.9 0.0 0.1 1.3 0.4 2.1 2.6 0.0 0.0 55.5 0.0 0.0 86.6 2.0 1.4 0.0 2.2 18.5 11.4 0.3 0.0 73.2 0.1 0.0 1.3 5.1 3.6 96.3 4.9 0.0 227.7 0.0 7.9 1.0 6.0 10.9 0.2 0.0 15.4 0.2 0.1 0.3 0.0 1.7 5.6 13.1 26.3 7.1 1.3 0.8 1.3 1.6 0.0 0.5 26.3 0.1 0.3 AC068631.2 ENSG00000283149 "Novel protein" 3 186581995-186597103 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA010814 Uncertain Uncertain "Endoplasmic reticulum" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" "Endoplasmic reticulum" "HPA010814: AB_1078691" 9.2 10.1 5.2 11.6 5.4 9.8 7.9 5.4 15.4 6.7 4.9 18.2 12.1 5.9 13.9 8.6 5.9 7.6 13.4 5.2 5.2 14.7 32.7 9.7 4.5 5.2 5.3 6.0 22.7 7.9 8.3 6.0 5.4 8.6 5.9 8.9 9.2 4.2 4.6 6.5 9.9 3.0 4.9 13.4 10.6 8.5 5.2 6.0 18.6 0.0 5.2 7.6 6.8 5.1 36.3 28.9 35.7 42.8 29.6 12.9 9.3 71.3 16.4 25.1 16.4 102.9 15.0 21.6 82.1 46.3 40.5 24.3 31.8 25.1 22.6 18.7 0.0 23.6 52.7 102.2 22.7 46.0 11.6 14.0 8.0 32.0 50.5 21.3 13.4 10.6 12.8 81.1 10.7 83.7 23.7 2.0 9.7 93.6 0.0 14.2 37.2 26.9 12.4 69.5 0.3 0.6 30.9 62.2 18.4 35.9 40.0 57.9 7.3 17.9 21.3 13.0 62.9 31.5 88.4 66.5 26.3 33.7 35.2 7.5 6.4 8.6 10.3 8.6 7.0 7.8 6.4 8.8 9.9 4.8 4.2 8.3 1.6 10.2 7.2 15.3 8.4 7.3 5.2 5.4 5.4 15.4 5.2 5.2 5.2 5.3 5.4 4.9 5.2 5.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC135050.2 ENSG00000255439 "Novel protein, VKORC1 and PRSS53 readthrough" 16 31083439-31094956 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "skin 1: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BJ: 5.2;NB-4: 6.8;RPMI-8226: 8.7;U-266/70: 5.7" HPA042720 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 24: NB-4 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "Endoplasmic reticulum" "HPA042720: AB_10961864" "unprognostic (2.74e-1)" "unprognostic (9.61e-2)" "unprognostic (6.94e-2)" "unprognostic (2.00e-1)" "unprognostic (1.59e-2)" "unprognostic (2.68e-3)" "unprognostic (2.45e-3)" "unprognostic (1.34e-1)" "unprognostic (3.57e-1)" "unprognostic (2.79e-2)" "unprognostic (4.48e-3)" "unprognostic (8.49e-2)" "unprognostic (2.84e-8)" "unprognostic (4.96e-6)" "unprognostic (1.39e-1)" "unprognostic (4.81e-1)" "unprognostic (2.29e-4)" 0.4 0.1 0.0 0.3 0.0 0.2 0.2 0.0 0.0 0.3 0.0 0.7 0.1 0.3 0.1 0.2 0.2 0.0 0.1 0.0 0.1 0.1 0.7 0.2 0.2 0.1 0.1 0.1 0.4 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.1 1.1 0.4 0.0 0.0 0.3 0.6 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.3 0.1 0.9 0.4 0.0 0.4 1.0 1.2 0.3 5.2 0.3 0.0 0.2 0.2 0.3 3.4 1.8 0.1 0.0 0.2 0.0 0.1 0.0 1.3 2.7 0.8 0.3 0.2 0.0 0.5 1.1 0.3 0.2 0.2 0.0 0.2 0.0 0.6 0.0 0.7 0.1 0.4 0.8 6.8 0.1 0.0 1.5 3.4 0.3 8.7 0.0 0.3 2.1 2.6 1.2 0.4 1.0 0.0 0.0 0.2 1.3 0.5 0.0 1.6 0.5 5.7 0.7 0.6 1.2 0.9 0.2 0.6 0.7 2.5 2.0 0.8 2.7 2.1 2.1 2.8 0.9 1.6 1.3 1.9 0.9 0.9 1.8 1.6 2.8 1.9 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 AC138811.2 ENSG00000260342 "Novel protein" 16 18788063-18801519 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "testis: 14.8" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 5.6;Club cells: 2.5;Endothelial cells: 2.0;granulocytes: 2.5;Macrophages: 1.8;Respiratory ciliated cells: 5.1" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "EFO-21: 52.4;HDLM-2: 69.2" HPA045307 Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 78: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "Endoplasmic reticulum" "HPA045307: AB_10961042" "unprognostic (1.03e-2)" "unprognostic (8.89e-3)" "unprognostic (1.22e-1)" "unprognostic (3.59e-3)" "unprognostic (2.28e-1)" "unprognostic (6.32e-2)" "unprognostic (1.30e-3)" "unprognostic (1.39e-1)" "unprognostic (1.47e-1)" "unprognostic (1.46e-1)" "unprognostic (1.40e-2)" "unprognostic (3.27e-1)" "unprognostic (3.18e-4)" "unprognostic (2.92e-1)" "unprognostic (3.89e-2)" "unprognostic (2.65e-2)" "unprognostic (3.95e-2)" 0.7 0.8 1.3 1.4 3.4 0.9 0.6 0.6 5.1 0.5 0.8 3.7 0.0 0.4 0.4 0.8 0.3 0.4 0.5 2.2 1.5 1.0 1.0 0.4 0.6 4.5 1.3 0.3 2.3 2.7 0.2 0.4 3.8 0.2 0.7 1.0 0.4 0.7 3.9 0.3 1.1 1.2 1.9 1.0 1.4 14.8 2.0 1.6 0.3 0.5 0.7 0.5 0.3 2.4 17.7 2.6 4.1 19.8 1.6 0.6 0.6 24.8 1.7 2.8 3.6 15.8 11.4 5.3 52.4 6.5 6.4 21.3 9.8 4.1 8.1 69.2 3.1 5.8 8.5 4.7 0.0 27.9 10.9 1.6 0.9 9.3 0.0 2.5 1.7 3.3 11.5 16.2 3.0 0.0 7.9 0.7 1.3 1.7 0.6 32.8 7.4 2.0 2.0 12.9 10.5 1.1 29.5 5.2 2.2 2.3 3.4 0.7 20.9 8.9 14.7 9.4 22.3 4.3 34.2 11.9 12.2 3.9 20.3 116.7 76.9 48.7 128.7 56.2 98.7 89.9 99.2 122.2 76.2 94.1 84.6 92.2 61.5 120.7 76.0 162.2 159.6 188.5 1.3 3.4 0.6 5.1 2.2 1.5 4.5 1.3 3.8 1.9 2.0 2.4 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 2.5 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 AF196969.1 ENSG00000286268 "Novel protein" X 48521806-48545469 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 4 "U-2197: 2.5" HPA003130 Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 18: U-2197 - ECM organization" "Endoplasmic reticulum" "HPA003130: AB_1078717" 0.0 0.1 0.1 0.1 0.1 0.2 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.3 0.0 0.2 0.3 0.0 0.1 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.3 0.4 0.2 0.1 0.2 0.1 0.3 0.2 0.1 0.3 0.2 0.2 0.1 0.5 0.1 0.0 0.0 0.2 0.0 0.3 0.1 0.0 0.1 0.2 0.2 0.1 0.2 0.2 0.2 0.4 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.6 0.2 0.0 0.2 0.0 0.3 2.5 0.1 0.1 0.2 0.0 0.4 0.2 0.0 0.0 0.1 0.0 0.4 0.2 0.3 0.1 0.2 0.2 0.0 0.1 0.1 0.2 0.1 0.1 0.3 0.3 0.1 0.2 0.1 0.1 0.6 0.2 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AGR2 "AG2, HAG-2, PDIA17, XAG-2" ENSG00000106541 "Anterior gradient 2, protein disulphide isomerase family member" O95994 7 16791811-16833433 "Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 638.7;intestine: 1224.0;stomach 1: 1402.3" "Cell type enhanced" "Detected in many" "Club cells: 1515.8;Distal enterocytes: 1026.4;Gastric mucus-secreting cells: 2605.5;Intestinal goblet cells: 3710.4;Paneth cells: 1101.6;Undifferentiated cells: 1543.1;Urothelial cells: 1017.8" "Cancer enhanced" "Detected in many" "stomach cancer: 475.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 15 "OE19: 20084.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA007912 Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA 38000 "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "Endoplasmic reticulum" "HPA007912: AB_1844879" "unprognostic (6.19e-2)" "unprognostic (1.91e-1)" "unprognostic (9.05e-2)" "unprognostic (2.59e-2)" "unprognostic (2.23e-1)" "unprognostic (2.10e-3)" "prognostic unfavorable (1.15e-4)" "unprognostic (1.49e-2)" "unprognostic (1.84e-1)" "unprognostic (1.08e-2)" "unprognostic (3.24e-1)" "unprognostic (2.22e-2)" "prognostic unfavorable (8.79e-5)" "unprognostic (6.98e-2)" "unprognostic (2.38e-1)" "unprognostic (2.38e-1)" "unprognostic (3.22e-3)" 2.1 0.7 0.0 66.6 0.0 0.0 72.3 0.2 0.5 638.7 0.0 768.1 486.0 14.1 389.1 16.2 306.4 275.8 0.2 0.1 0.0 11.2 0.9 50.7 0.6 0.0 0.1 0.3 22.1 0.1 31.4 1.6 0.0 227.3 1224.0 0.0 475.3 181.0 0.2 2.5 379.2 45.2 0.0 0.9 1402.3 0.9 0.0 1.7 7.4 0.1 7.2 160.8 4.0 0.1 0.3 265.5 0.0 0.3 0.0 0.1 2.6 0.0 0.0 0.0 0.0 43.5 39.7 0.0 0.2 0.0 6.6 25.2 0.0 34.5 0.2 0.0 0.0 0.0 0.9 3.8 0.0 0.0 1.0 0.0 88.5 0.0 11.4 0.4 0.4 0.3 0.0 0.0 0.2 44.7 1.3 1.8 0.8 20084.0 154.2 1.0 0.0 5.2 631.3 371.6 1.7 2.1 0.0 98.8 0.0 1.0 1319.9 0.0 0.0 0.7 1.2 0.9 0.2 1.2 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.1 51.3 293.1 0.0 19.0 2.8 127.1 539.8 0.6 0.0 169.3 137.4 0.2 268.8 1515.8 80.9 0.0 6.0 0.4 1026.4 0.0 74.1 4.6 301.9 33.9 4.8 522.1 0.0 0.1 835.1 4.5 6.0 2605.5 365.3 43.9 0.0 0.0 1.7 240.8 0.0 0.1 3710.4 386.6 0.8 0.3 0.4 0.3 6.5 3.6 0.0 1.0 0.0 0.0 0.0 0.0 303.1 1101.6 0.0 2.6 426.9 517.9 0.2 781.0 0.0 0.0 0.0 76.9 0.4 0.2 5.3 2.8 3.3 13.1 0.0 1543.1 1017.8 AL035078.4 ENSG00000285283 "Novel protein" 11 31812391-32104665 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 8.8;lymphoid tissue: 5.7;retina: 7.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BJ: 224.4;RH-30: 110.7;RT4: 139.0;TIME: 116.0" HPA038474 Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" "Endoplasmic reticulum" "HPA038474: AB_10672595" 1.3 0.0 0.4 5.7 0.7 0.5 0.0 2.5 1.4 0.3 0.0 8.8 0.0 2.3 0.1 2.2 0.7 0.0 0.0 0.4 1.3 0.3 1.6 1.0 0.0 1.5 1.2 1.1 0.0 0.0 0.4 1.1 0.2 0.2 7.4 0.0 0.0 4.1 0.0 1.5 0.2 1.0 0.2 2.1 0.5 0.8 0.3 0.0 0.0 0.5 0.1 1.6 14.7 33.3 4.9 22.6 2.8 0.0 0.6 224.4 40.6 18.6 9.5 11.2 25.0 0.0 46.0 12.7 14.3 7.1 21.8 12.1 14.7 13.1 0.8 13.4 24.1 0.0 0.0 11.3 1.8 0.0 0.0 23.7 6.4 3.8 4.4 0.1 3.7 13.5 0.0 0.2 13.8 0.0 2.6 0.0 0.3 8.7 110.7 2.7 0.0 139.0 12.9 3.7 36.6 1.4 16.3 0.0 13.9 0.5 116.0 62.2 27.3 30.4 64.6 0.0 0.1 0.6 74.6 2.9 24.7 0.0 0.8 0.0 0.3 0.4 0.4 0.2 0.0 0.2 1.0 0.0 0.0 0.1 0.1 0.8 0.3 0.1 0.0 0.4 0.4 0.7 2.5 1.4 0.4 1.3 1.5 1.2 1.1 1.0 0.8 1.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ALG10 "ALG10A, DIE2, FLJ14751" ENSG00000139133 "ALG10 alpha-1,2-glucosyltransferase" Q5BKT4 12 34022468-34029694 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Spermatocytes: 12.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "HPA043329, HPA063387" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 5: NTERA-2 - Transcription" "Cluster 12: Non-specific - Cell cycle regulation" "Endoplasmic reticulum" "HPA043329: AB_2678432, HPA063387: AB_2685000" "unprognostic (1.71e-1)" "unprognostic (4.98e-2)" "unprognostic (3.16e-3)" "unprognostic (2.80e-2)" "unprognostic (9.23e-2)" "unprognostic (3.49e-2)" "unprognostic (5.88e-4)" "unprognostic (2.13e-1)" "unprognostic (1.73e-2)" "unprognostic (8.01e-2)" "unprognostic (5.41e-2)" "unprognostic (1.16e-1)" "unprognostic (9.29e-2)" "unprognostic (8.99e-2)" "unprognostic (1.53e-1)" "unprognostic (2.43e-1)" "unprognostic (6.45e-2)" 2.3 2.6 1.3 2.7 1.5 4.1 2.8 1.7 1.1 1.9 0.9 2.3 1.6 2.2 2.7 2.1 3.4 1.8 1.0 0.8 1.5 1.9 2.9 1.8 3.7 1.9 1.2 2.3 1.5 2.3 0.6 2.3 1.6 2.6 1.9 3.3 1.5 1.9 0.9 1.9 1.8 2.1 1.6 2.9 2.0 2.6 1.3 3.6 2.8 1.3 2.9 1.3 0.9 2.2 5.3 5.8 4.0 7.0 4.6 4.3 14.0 5.1 4.7 5.4 9.8 8.8 12.6 10.3 7.3 2.6 8.2 7.8 7.9 6.8 7.9 13.0 7.2 9.2 6.7 3.9 1.8 11.4 8.1 4.0 3.6 11.3 9.3 2.6 3.7 8.1 13.9 13.6 5.5 6.8 8.4 6.3 15.1 3.2 7.7 6.5 14.8 8.3 3.2 7.8 3.8 3.0 9.4 3.8 5.6 11.7 8.6 3.2 7.5 7.4 10.7 11.3 6.5 7.4 14.7 17.3 5.0 4.8 6.2 0.0 1.0 1.7 0.6 0.4 0.9 0.8 0.9 0.4 0.6 0.8 1.1 1.3 0.1 0.8 0.5 0.7 1.2 0.5 1.3 1.5 1.7 1.1 0.8 1.5 1.9 1.2 1.6 1.6 1.3 2.2 3.0 6.4 0.5 1.3 5.1 1.5 3.0 4.3 2.8 4.6 2.0 1.7 0.8 2.8 5.1 5.5 4.2 6.8 3.5 1.4 1.9 2.4 1.0 3.1 2.8 2.3 1.2 7.0 1.5 3.8 5.5 2.7 3.1 2.2 1.3 3.6 0.7 2.9 3.3 1.7 1.8 1.7 2.0 2.8 1.9 0.3 1.5 2.2 0.0 1.9 3.3 3.4 1.0 2.5 1.8 3.3 0.6 1.2 4.0 0.8 1.2 1.3 3.9 4.2 0.0 2.5 2.0 12.4 5.8 4.3 2.7 3.1 3.2 2.6 1.9 1.8 ALG10B KCR1 ENSG00000175548 "ALG10 alpha-1,2-glucosyltransferase B" Q5I7T1 12 38316762-38329721 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 33.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "HPA043329, HPA063387" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" "Endoplasmic reticulum" "HPA043329: AB_2678432, HPA063387: AB_2685000" "unprognostic (4.55e-2)" "unprognostic (1.01e-1)" "unprognostic (2.32e-1)" "unprognostic (1.25e-1)" "unprognostic (1.79e-1)" "unprognostic (3.01e-1)" "unprognostic (4.43e-2)" "unprognostic (8.58e-2)" "unprognostic (7.40e-2)" "unprognostic (8.40e-2)" "unprognostic (1.17e-1)" "unprognostic (2.05e-2)" "unprognostic (1.91e-1)" "unprognostic (3.30e-3)" "unprognostic (2.63e-1)" "unprognostic (1.93e-1)" "unprognostic (2.28e-1)" 2.9 3.5 2.1 3.0 2.3 4.3 5.2 3.1 2.5 2.8 1.8 2.1 2.4 3.7 3.7 1.8 3.4 2.6 2.2 1.8 2.0 3.3 3.7 2.5 4.6 2.5 2.3 5.0 2.9 3.7 1.1 5.0 2.6 3.4 2.6 9.1 2.8 2.2 1.5 4.3 2.6 2.5 2.6 4.6 3.7 2.6 2.2 4.0 4.2 2.4 3.7 1.5 1.4 3.1 5.1 4.6 6.1 6.2 3.0 5.5 6.3 4.0 2.0 5.3 4.6 1.7 15.2 8.0 7.2 2.3 4.1 5.3 5.7 4.4 7.6 5.2 6.8 8.4 8.4 3.5 3.5 11.3 6.1 3.1 5.7 7.5 5.5 4.7 4.2 10.4 9.6 4.6 4.8 3.9 7.5 8.9 7.8 0.5 4.6 2.5 13.2 6.3 4.4 6.4 1.8 6.3 7.1 2.3 5.0 6.6 10.6 4.6 3.3 5.5 6.6 4.9 5.2 3.6 10.1 12.5 4.7 7.7 7.3 0.3 0.4 0.6 0.3 0.5 0.5 0.4 0.3 0.4 0.3 1.3 0.5 0.7 0.1 0.4 0.4 0.7 1.2 0.3 2.1 2.3 3.1 2.5 1.8 2.0 2.5 2.3 2.6 2.6 2.2 3.1 7.1 6.4 13.9 9.1 2.6 2.0 3.4 3.3 4.0 14.9 5.0 3.8 3.9 0.0 7.0 3.7 33.3 16.1 2.1 0.9 7.9 4.3 0.3 6.5 6.2 5.7 0.0 2.5 4.8 5.8 9.6 4.8 2.0 4.6 1.3 9.5 6.8 7.1 4.8 10.1 5.7 1.9 4.1 1.6 2.0 1.8 4.1 3.1 1.8 10.3 2.5 8.0 1.0 9.0 9.1 4.5 2.0 5.7 1.6 2.0 2.6 2.6 5.2 14.5 6.6 6.5 3.2 10.7 4.7 3.1 1.8 8.1 3.0 4.6 2.3 2.3 ALG12 "CDG1G, ECM39" ENSG00000182858 "ALG12 alpha-1,6-mannosyltransferase" Q9BV10 22 49900229-49918438 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003076, HPA051665" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 18: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "HPA003076: AB_2666777, HPA051665: AB_2681566" "unprognostic (1.66e-1)" "unprognostic (1.26e-1)" "unprognostic (4.39e-3)" "prognostic favorable (6.09e-4)" "unprognostic (2.29e-1)" "unprognostic (3.32e-2)" "unprognostic (4.27e-3)" "unprognostic (3.33e-2)" "unprognostic (1.46e-1)" "unprognostic (3.32e-2)" "unprognostic (1.42e-1)" "unprognostic (2.21e-1)" "prognostic favorable (3.60e-5)" "unprognostic (1.62e-2)" "unprognostic (3.00e-2)" "unprognostic (9.89e-3)" "unprognostic (6.32e-2)" 6.3 8.0 3.5 7.3 4.5 5.9 6.4 6.2 4.7 7.6 4.9 8.8 11.1 8.3 6.5 8.0 7.6 6.6 8.3 3.9 2.6 10.3 14.5 7.0 5.6 4.5 4.3 7.1 11.4 11.8 6.6 5.4 4.7 9.1 4.1 3.0 12.0 5.6 6.1 7.2 8.9 4.4 3.3 7.2 10.3 4.5 4.9 6.5 11.7 4.5 4.8 7.7 6.8 8.4 8.6 8.5 8.8 14.7 16.4 7.6 9.8 8.8 7.9 10.2 8.2 14.0 12.0 4.6 7.8 7.8 11.1 15.2 10.7 10.4 5.0 7.3 15.9 4.2 14.7 14.1 18.6 10.6 8.9 11.6 10.5 9.9 14.3 11.2 9.9 10.3 5.3 11.2 5.4 19.6 10.4 8.6 8.4 11.3 7.7 17.2 11.0 12.1 10.6 9.6 5.9 9.6 14.0 26.3 11.4 11.7 10.8 9.4 7.7 11.2 8.5 7.9 6.8 9.8 4.9 6.1 12.5 8.0 10.9 21.4 8.7 7.7 11.5 8.5 11.7 4.8 8.9 11.4 7.6 6.4 7.3 8.6 7.1 16.9 10.1 7.7 12.8 8.1 3.5 4.5 6.2 4.7 3.9 2.6 4.5 4.3 4.7 3.3 4.9 8.4 6.8 9.6 3.1 21.5 10.2 4.1 10.2 12.1 9.1 5.2 11.1 10.2 1.2 8.6 10.3 18.4 2.1 20.5 8.5 16.6 3.9 15.9 6.9 6.6 8.0 8.1 6.7 7.4 23.2 13.5 22.4 10.6 11.7 9.2 8.2 7.0 5.3 15.0 18.6 3.3 30.4 12.9 12.2 9.2 5.3 4.3 8.7 8.7 10.6 9.4 9.0 2.9 18.6 17.6 40.4 10.3 9.7 8.2 15.6 11.3 18.8 6.8 5.6 5.2 0.0 8.5 7.7 12.9 9.1 10.4 6.0 26.3 11.9 8.3 16.3 9.1 ALG6 ENSG00000088035 "ALG6 alpha-1,3-glucosyltransferase" Q9Y672 1 63367575-63438553 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "NTERA-2: 7.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062536, HPA076130" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 5: NTERA-2 - Transcription" "Cluster 47: Cytotrophoblasts - Unknown function" "Endoplasmic reticulum" "HPA062536: AB_2684792, HPA076130: " "unprognostic (1.21e-1)" "unprognostic (5.60e-3)" "prognostic favorable (4.86e-4)" "unprognostic (1.59e-1)" "unprognostic (3.45e-1)" "unprognostic (2.45e-2)" "prognostic unfavorable (9.46e-4)" "unprognostic (2.07e-1)" "unprognostic (9.81e-3)" "unprognostic (4.65e-2)" "unprognostic (2.00e-2)" "unprognostic (3.90e-2)" "prognostic unfavorable (2.63e-6)" "unprognostic (1.84e-3)" "unprognostic (1.07e-1)" "unprognostic (4.61e-2)" "unprognostic (3.41e-1)" 3.5 4.5 1.1 1.1 1.3 1.4 3.4 1.9 1.4 3.7 1.0 3.8 1.1 2.9 1.4 6.1 3.0 0.8 2.1 1.1 1.2 3.0 4.6 2.7 1.9 1.1 1.2 3.2 3.3 1.4 2.0 1.0 1.1 3.1 1.2 1.2 4.3 0.6 2.8 5.1 4.4 0.6 1.1 5.2 3.2 2.2 1.1 2.0 3.1 0.1 1.6 3.1 4.2 1.4 0.5 1.3 1.3 1.2 1.8 1.3 2.6 0.9 0.2 0.3 0.3 2.0 0.6 2.7 1.4 0.7 1.5 1.0 2.0 1.0 1.4 2.4 4.2 2.2 1.5 2.4 0.6 2.8 2.4 0.9 0.6 0.9 0.6 0.7 2.0 2.3 2.2 1.3 1.0 2.5 1.7 2.4 7.6 1.3 2.3 1.8 1.6 2.1 1.6 2.2 1.5 0.8 2.3 3.2 2.3 2.9 0.9 2.1 0.9 0.6 0.6 1.8 1.5 1.7 1.7 1.7 1.2 3.3 2.4 1.3 0.3 0.4 0.3 0.3 0.4 0.3 0.3 0.2 0.3 0.3 0.6 0.5 0.1 0.4 0.3 0.2 0.3 0.2 1.1 1.3 1.9 1.4 1.1 1.2 1.1 1.2 1.1 1.1 1.1 1.4 9.8 9.6 4.8 9.8 12.1 11.0 8.5 24.6 15.4 6.3 8.5 5.5 3.1 12.8 22.1 3.7 4.2 42.1 10.2 6.1 1.9 12.4 2.4 11.2 7.0 8.7 4.2 9.0 19.1 8.9 28.5 8.6 11.2 10.0 8.9 12.2 8.2 11.5 15.5 6.7 19.4 7.8 22.4 7.1 8.8 2.0 6.8 9.1 16.0 4.7 4.8 5.5 13.4 19.1 16.8 6.0 3.6 4.9 11.4 4.9 8.2 7.3 11.7 5.4 6.6 4.5 6.6 16.2 15.3 18.3 11.1 26.8 15.1 10.0 11.5 7.4 ALG9 DIBD1 ENSG00000086848 "ALG9 alpha-1,2-mannosyltransferase" Q9H6U8 11 111782195-111871581 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 26.6;Inhibitory neurons: 31.8;Oligodendrocytes: 31.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA038575 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 59: Non-specific - Transcription" "Endoplasmic reticulum" "HPA038575: AB_10672718" "unprognostic (1.48e-1)" "unprognostic (5.39e-2)" "unprognostic (6.22e-2)" "unprognostic (5.34e-3)" "unprognostic (8.72e-2)" "unprognostic (2.90e-1)" "unprognostic (2.43e-2)" "unprognostic (1.04e-2)" "unprognostic (7.07e-3)" "unprognostic (5.11e-2)" "unprognostic (8.75e-3)" "unprognostic (1.52e-2)" "prognostic unfavorable (7.29e-5)" "unprognostic (9.15e-2)" "unprognostic (7.76e-2)" "unprognostic (4.20e-2)" "unprognostic (1.10e-2)" 14.0 9.7 6.3 8.6 7.1 7.8 12.4 8.2 7.8 12.9 6.3 10.9 12.1 11.5 10.9 11.4 9.2 7.9 10.1 6.3 6.6 9.5 13.4 9.6 6.6 6.5 6.8 12.5 19.7 12.7 10.0 9.6 6.7 9.6 10.3 12.0 17.5 11.3 9.1 15.2 10.2 11.1 5.6 8.4 12.0 13.6 6.1 9.8 12.3 8.3 9.2 11.3 11.1 6.4 16.6 16.5 30.7 31.1 19.0 18.0 23.7 20.5 16.5 16.4 17.9 28.7 27.4 27.1 28.7 23.8 21.4 29.8 16.6 25.4 23.4 20.2 12.2 19.7 8.6 21.2 22.0 22.2 13.6 15.5 17.2 17.7 17.8 24.2 16.2 20.2 20.3 41.0 28.4 12.5 22.2 20.3 10.7 23.3 15.9 20.4 26.9 51.5 18.5 13.7 15.0 25.4 18.0 28.0 11.4 21.6 29.0 9.3 16.9 35.0 25.2 17.1 22.6 13.3 10.2 24.4 15.1 27.4 24.7 4.5 3.1 3.8 4.0 4.5 4.7 4.0 4.1 4.6 5.2 3.1 5.8 3.6 1.1 4.2 4.0 5.6 4.5 3.3 6.3 7.1 8.2 7.8 6.3 6.6 6.5 6.8 6.7 5.6 6.1 6.4 3.2 0.0 4.4 21.5 5.9 2.0 1.5 3.2 9.6 8.9 3.8 3.4 5.6 1.5 3.9 7.3 8.4 3.5 4.6 3.2 3.9 7.5 5.1 2.0 5.2 4.1 4.2 6.3 26.6 7.1 12.6 4.7 4.6 3.8 0.0 5.5 2.2 6.8 3.2 15.2 31.8 4.0 4.1 1.9 1.9 4.3 4.7 3.5 0.0 12.2 3.1 4.9 3.1 21.1 31.8 6.5 2.9 3.8 22.8 1.3 4.6 2.3 2.2 9.7 6.6 3.5 5.4 4.2 5.7 8.6 1.6 9.0 5.8 2.5 4.4 0.8 ANKRD16 DKFZP434N1511 ENSG00000134461 "Ankyrin repeat domain 16" Q6P6B7 10 5861616-5889906 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 26.9;Inhibitory neurons: 28.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037920, HPA037921" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "HPA037920: AB_10671381, HPA037921: AB_2675740" "unprognostic (1.90e-1)" "unprognostic (1.67e-1)" "unprognostic (5.94e-3)" "unprognostic (2.15e-1)" "unprognostic (1.73e-2)" "unprognostic (6.18e-3)" "unprognostic (9.96e-3)" "unprognostic (4.57e-2)" "unprognostic (3.05e-1)" "unprognostic (1.86e-2)" "prognostic favorable (1.98e-4)" "unprognostic (5.85e-2)" "prognostic unfavorable (4.31e-7)" "unprognostic (1.06e-2)" "unprognostic (7.64e-2)" "unprognostic (9.53e-2)" "unprognostic (3.93e-2)" 3.8 4.0 5.5 2.3 5.5 1.9 4.1 5.6 7.9 6.3 3.1 3.7 3.2 5.1 4.9 3.7 5.8 2.5 3.3 5.2 4.2 3.5 4.1 3.0 3.1 5.0 4.5 6.2 4.1 5.7 3.9 1.7 5.2 4.1 2.5 4.4 4.0 3.1 3.9 6.7 3.2 3.2 4.0 3.2 6.6 8.7 4.8 3.8 3.7 2.6 3.3 4.3 4.4 5.6 8.3 9.8 4.5 9.2 4.6 3.4 6.6 2.5 1.9 4.4 3.8 12.1 4.3 8.8 3.5 4.2 1.6 8.5 5.5 6.4 2.0 3.1 8.6 5.5 4.8 11.1 5.9 3.4 3.8 5.3 4.8 4.0 3.1 3.5 4.9 9.0 7.5 2.6 3.1 11.5 12.7 5.8 3.7 11.2 6.9 9.6 2.9 18.1 5.0 5.3 2.7 6.0 5.2 6.4 6.0 3.6 8.9 6.9 3.2 2.6 3.4 5.8 3.5 14.7 7.1 5.8 5.4 3.3 2.9 0.3 0.2 0.0 0.1 0.1 0.1 0.3 0.1 0.2 0.2 0.4 0.4 0.1 0.1 0.4 0.1 0.5 0.2 0.1 5.5 5.5 5.6 7.9 5.2 4.2 5.0 4.5 5.2 4.0 4.8 5.6 5.3 3.2 1.3 14.7 5.9 4.7 7.8 1.4 4.6 14.1 7.0 6.0 2.8 10.0 1.8 3.7 6.2 4.7 3.0 2.4 13.7 2.1 8.4 7.8 9.8 4.2 4.2 5.5 25.1 2.2 3.6 10.2 4.1 4.4 0.0 13.0 3.3 3.8 3.3 26.9 28.4 3.1 0.0 1.0 3.3 14.6 5.6 3.2 3.6 5.6 3.6 8.8 1.0 12.5 16.2 1.0 1.3 3.8 11.3 7.3 5.2 8.3 1.0 14.4 0.0 8.5 4.5 13.0 7.8 6.5 5.7 1.5 3.5 10.5 5.2 3.7 AP001781.2 ENSG00000258529 "Novel protein" 11 111786286-111879425 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "CACO-2: 2.8;HeLa: 3.0" HPA038575 Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 20: HeLa - Mitochondria" "Cluster 11: Alveolar cells - Smell perception" "Endoplasmic reticulum" "HPA038575: AB_10672718" 0.6 0.0 0.0 0.2 0.0 0.6 0.3 0.0 0.6 0.0 0.0 0.7 0.7 0.4 0.3 0.1 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.5 0.2 0.1 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.2 0.4 0.4 0.0 0.0 0.2 0.7 0.0 0.2 0.1 0.3 0.3 1.1 0.1 0.4 0.2 0.2 0.4 0.0 0.0 0.1 0.1 0.0 0.5 0.5 0.0 0.7 0.1 0.8 0.0 0.1 0.0 2.8 0.0 0.1 0.5 0.0 0.8 1.0 0.0 0.0 0.6 0.2 0.0 1.7 3.0 0.2 0.0 0.0 0.3 1.0 1.0 0.7 1.5 0.4 0.0 1.0 0.1 1.0 0.0 0.0 0.6 1.3 0.2 0.0 0.0 0.0 0.0 1.1 0.4 0.9 0.0 0.0 0.7 0.0 0.1 0.0 0.6 0.6 0.0 1.2 0.3 0.5 0.1 0.8 0.7 2.1 0.3 1.5 0.2 0.3 0.5 0.5 1.2 0.6 0.8 0.5 0.7 0.7 0.6 0.6 1.3 0.6 0.0 0.7 0.5 0.7 0.2 1.1 0.0 0.0 0.0 0.6 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ARL6IP1 "AIP1, ARL6IP, ARMER, KIAA0069, SPG61" ENSG00000170540 "ADP ribosylation factor like GTPase 6 interacting protein 1" Q15041 16 18791669-18801572 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045307 Uncertain Approved "Endoplasmic reticulum" NA Yes "Cluster 44: Non-specific - Transcription" "Cluster 58: Brain - Synaptic function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 12: Non-specific - Cell cycle regulation" "Endoplasmic reticulum" "HPA045307: AB_10961042" "unprognostic (2.42e-1)" "unprognostic (3.47e-2)" "unprognostic (4.07e-3)" "unprognostic (1.12e-1)" "unprognostic (1.54e-1)" "unprognostic (2.60e-3)" "unprognostic (2.58e-2)" "unprognostic (1.76e-2)" "unprognostic (3.88e-2)" "unprognostic (6.83e-2)" "unprognostic (1.91e-3)" "unprognostic (3.33e-2)" "unprognostic (1.13e-2)" "unprognostic (7.09e-2)" "unprognostic (4.60e-2)" "unprognostic (6.32e-3)" "unprognostic (5.36e-3)" 142.0 171.3 206.4 77.7 217.3 209.7 112.9 200.6 282.2 79.2 182.4 140.9 138.8 70.8 122.9 70.0 86.6 131.9 32.1 227.7 209.2 150.1 359.6 79.6 132.6 192.0 197.8 101.6 81.7 180.6 40.7 90.3 200.0 75.9 123.4 316.0 84.3 70.4 23.1 66.1 123.4 69.1 185.0 72.8 125.8 129.9 200.5 158.5 112.5 51.5 113.4 132.5 47.4 197.6 375.3 334.6 417.8 331.6 146.7 93.5 373.2 208.9 196.9 311.0 246.7 205.7 851.1 315.7 388.4 198.0 209.2 388.9 303.7 144.2 359.1 421.2 137.1 227.9 192.5 549.1 116.4 329.9 232.0 78.6 137.7 216.2 224.0 229.1 316.1 180.5 251.0 318.5 607.6 331.4 229.9 238.3 520.0 311.7 109.8 387.9 535.9 266.0 337.8 206.1 255.2 287.5 466.5 279.8 204.5 280.1 576.1 315.9 189.2 204.2 192.9 147.1 384.1 109.5 209.5 383.2 182.8 215.6 405.5 211.4 125.2 84.2 179.4 119.5 167.0 163.2 159.0 199.1 127.4 160.7 137.9 166.4 105.9 179.2 133.3 221.6 281.5 295.0 206.4 217.3 200.6 282.2 227.7 209.2 192.0 197.8 200.0 185.0 200.5 197.6 306.4 67.3 51.0 56.8 170.6 372.6 241.4 170.1 309.6 189.2 256.5 216.8 30.6 361.8 128.7 286.9 131.3 296.7 164.6 269.0 174.1 398.2 74.6 93.3 61.7 188.1 145.9 503.8 70.4 203.1 385.4 150.4 257.9 158.3 135.8 198.0 275.5 457.4 253.9 89.2 94.2 234.6 229.9 275.8 424.6 42.7 84.8 205.8 200.9 39.4 267.3 318.5 142.2 57.3 50.3 271.0 288.5 110.9 107.5 219.4 217.0 189.1 126.6 218.0 92.1 125.6 118.6 193.6 56.6 295.2 326.5 326.6 186.9 53.1 319.7 323.8 ARL6IP5 "DERP11, GTRAP3-18, HSPC127, JWA, PRAF3, Yip6b" ENSG00000144746 "ADP ribosylation factor like GTPase 6 interacting protein 5" O75915 3 69084937-69106092 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015540, CAB019321" Supported Approved "Endoplasmic reticulum" NA NA 1100000 "Cluster 44: Non-specific - Transcription" "Cluster 38: Heart - Muscle contraction" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 3: Monocytes - Immune response regulation" "Endoplasmic reticulum" "CAB019321: , HPA015540: AB_1852061" "unprognostic (8.01e-2)" "unprognostic (1.71e-1)" "unprognostic (8.09e-2)" "unprognostic (1.51e-3)" "unprognostic (2.65e-1)" "unprognostic (3.51e-1)" "unprognostic (1.65e-1)" "unprognostic (1.84e-1)" "unprognostic (3.06e-1)" "unprognostic (3.72e-3)" "unprognostic (1.31e-2)" "unprognostic (7.23e-2)" "unprognostic (2.05e-3)" "unprognostic (3.60e-1)" "unprognostic (4.44e-2)" "unprognostic (3.42e-2)" "unprognostic (1.31e-2)" 157.7 130.6 91.0 109.9 95.9 67.8 139.7 100.6 156.0 123.0 83.1 87.3 59.1 72.8 104.4 78.3 90.5 102.1 216.3 91.1 105.6 88.5 80.3 125.5 138.3 100.6 93.4 74.2 55.3 83.4 47.6 88.8 106.8 129.6 85.2 135.0 159.6 90.5 183.2 48.5 66.1 100.4 104.1 100.3 72.5 34.9 98.3 92.3 71.2 186.8 130.0 111.8 61.0 113.3 86.9 59.0 71.1 52.8 361.4 335.2 89.7 87.9 196.5 66.7 77.4 30.1 205.9 17.0 28.9 151.1 124.8 67.0 59.2 100.8 57.0 339.5 55.2 59.6 91.1 45.8 92.9 51.4 280.5 243.6 177.5 61.5 77.3 235.0 206.0 55.7 26.6 156.7 163.6 50.3 56.0 67.0 18.5 200.2 55.1 48.6 65.0 159.1 330.5 143.1 17.8 47.0 87.0 93.5 119.5 69.7 61.7 80.2 203.7 44.1 34.8 112.5 96.1 139.4 208.5 31.7 146.0 126.0 72.8 697.4 388.2 650.2 332.4 357.6 257.1 397.7 462.4 427.6 275.7 336.1 391.2 409.5 162.0 298.4 315.1 176.0 530.4 933.9 91.0 95.9 100.6 156.0 91.1 105.6 100.6 93.4 106.8 104.1 98.3 113.3 101.1 176.3 132.0 34.6 183.6 72.8 70.6 275.5 108.7 201.9 214.9 174.5 422.0 95.8 185.0 93.8 187.7 305.8 212.7 146.7 25.4 281.4 20.8 144.9 79.5 121.4 42.0 89.8 45.9 214.4 379.2 254.8 64.2 233.4 336.6 75.7 150.3 72.5 292.0 122.8 70.7 57.1 270.6 260.0 402.1 18.9 207.2 275.4 272.1 35.6 476.6 235.7 272.9 49.8 97.0 244.2 95.7 261.8 93.4 93.6 91.7 77.8 155.0 272.4 190.7 190.3 125.4 7.3 4.3 207.8 73.9 178.4 292.2 133.6 77.8 94.0 ASPH "BAH, CASQ2BP1, HAAH, JCTN" ENSG00000198363 "Aspartate beta-hydroxylase" Q12797 8 61500556-61714640 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Dioxygenase, Oxidoreductase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 386.9" "Cell type enhanced" "Detected in all" "Muller glia cells: 468.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 34.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-87 MG: 890.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055161, HPA059303" Uncertain Enhanced "Endoplasmic reticulum" NA NA 1100000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 5: Muller glia cells - Visual perception" "Endoplasmic reticulum" "HPA055161: AB_2682721, HPA059303: AB_2683973" "unprognostic (8.07e-2)" "prognostic unfavorable (8.07e-5)" "unprognostic (1.73e-2)" "unprognostic (4.48e-2)" "unprognostic (2.32e-1)" "unprognostic (1.85e-2)" "unprognostic (2.82e-2)" "prognostic unfavorable (3.61e-4)" "unprognostic (6.39e-2)" "unprognostic (3.64e-1)" "prognostic unfavorable (1.75e-4)" "unprognostic (9.50e-2)" "prognostic unfavorable (1.57e-5)" "unprognostic (8.96e-2)" "unprognostic (1.65e-1)" "prognostic unfavorable (4.24e-4)" "unprognostic (2.74e-2)" 386.9 160.3 64.7 50.6 69.2 16.9 106.9 102.3 88.9 65.6 84.4 78.8 45.6 49.3 44.7 71.4 46.9 61.0 111.3 64.5 58.4 59.5 74.9 74.1 20.3 54.0 69.2 62.2 44.7 38.7 36.3 47.9 52.2 48.3 84.9 219.5 101.9 70.2 357.6 35.2 45.5 67.5 44.8 28.6 105.0 16.5 71.8 16.7 97.0 182.7 28.5 112.2 43.8 60.4 460.3 652.3 89.9 55.1 392.1 370.1 31.2 804.0 741.3 336.3 350.1 113.1 594.2 35.3 54.3 474.6 270.3 167.5 56.2 281.1 570.0 13.6 57.0 81.1 372.5 310.3 251.2 12.5 12.9 306.5 61.9 187.6 237.4 657.2 144.8 18.0 22.2 32.1 300.2 97.4 3.3 16.6 51.7 441.6 383.4 22.3 97.0 7.3 206.2 374.0 93.1 32.1 249.9 116.1 101.7 49.0 47.7 22.2 456.7 338.0 174.3 313.0 288.0 20.2 27.1 1.5 890.1 7.5 231.4 1.9 8.3 0.3 2.5 2.9 4.7 5.5 3.5 2.4 10.0 5.0 4.9 2.5 25.4 8.7 1.8 34.0 4.0 4.1 64.7 69.2 102.3 88.9 64.5 58.4 54.0 69.2 52.2 44.8 71.8 60.4 79.1 195.5 244.0 366.6 13.8 47.0 160.7 126.0 68.9 138.3 83.7 58.4 228.6 37.1 157.5 86.5 294.0 118.1 40.3 57.0 15.6 144.2 1.6 51.4 65.8 85.9 116.5 13.0 93.1 180.4 107.1 132.0 73.9 115.4 8.2 34.5 42.8 62.6 72.2 127.9 98.9 215.1 52.9 26.6 44.1 3.1 70.8 48.1 42.7 61.8 20.0 468.8 2.1 154.8 53.5 257.7 32.3 57.6 15.9 148.2 34.3 34.6 66.6 158.8 46.0 114.4 92.7 3.4 16.8 101.7 50.3 48.0 13.6 131.2 67.3 254.2 ASTE1 HT001 ENSG00000034533 "Asteroid homolog 1" Q2TB18 3 131013875-131027649 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 42.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037010, HPA037011" Supported Approved "Endoplasmic reticulum" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Endoplasmic reticulum" "HPA037010: AB_10673629, HPA037011: AB_10696929" "unprognostic (7.42e-2)" "prognostic favorable (3.09e-4)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.34e-4)" "unprognostic (2.56e-1)" "unprognostic (1.03e-2)" "prognostic unfavorable (4.03e-5)" "unprognostic (2.27e-3)" "unprognostic (2.80e-2)" "unprognostic (1.89e-2)" "unprognostic (2.22e-1)" "unprognostic (1.38e-2)" "unprognostic (2.58e-2)" "unprognostic (1.65e-1)" "unprognostic (3.56e-1)" "unprognostic (1.41e-2)" "unprognostic (4.64e-2)" 3.4 3.2 2.9 4.9 3.3 6.7 5.5 6.1 4.8 6.0 3.4 5.4 5.8 3.8 5.9 3.7 4.5 3.9 2.9 3.2 2.5 3.7 6.1 4.1 7.0 2.5 2.8 5.7 3.3 5.0 3.3 3.9 3.0 3.8 5.8 4.7 3.1 4.2 2.3 4.1 7.1 3.4 2.9 4.4 4.7 6.1 3.3 7.2 7.0 2.8 6.8 3.9 2.9 4.6 9.7 7.1 4.5 4.7 7.7 8.4 1.9 5.4 4.6 6.4 7.0 11.4 4.2 10.8 8.2 5.5 5.5 10.5 9.1 4.4 9.6 5.8 5.3 6.4 3.6 5.4 7.9 9.9 3.6 5.3 6.1 5.2 4.9 5.7 5.4 8.7 5.9 5.3 6.7 6.6 9.0 5.2 4.1 11.6 6.8 9.4 6.4 9.4 5.2 5.9 7.7 7.2 10.5 2.4 7.6 4.3 6.3 6.9 3.8 7.2 4.8 12.1 4.3 6.6 6.5 14.0 5.6 8.5 3.6 51.2 13.0 28.4 20.4 15.3 21.3 15.5 22.0 17.7 14.5 16.5 28.3 21.2 9.4 29.4 20.9 10.7 28.2 11.8 2.9 3.3 6.1 4.8 3.2 2.5 2.5 2.8 3.0 2.9 3.3 4.6 6.5 12.8 5.8 7.5 14.6 3.2 3.7 4.8 2.2 9.2 5.1 7.4 1.8 4.3 6.3 3.7 14.6 6.0 17.5 11.1 5.9 4.9 42.1 4.5 5.8 6.9 6.7 6.1 8.3 6.0 4.8 5.1 8.6 4.6 8.8 7.0 10.0 5.6 4.8 3.3 6.3 7.0 4.1 5.7 2.0 12.6 7.2 7.2 1.8 5.6 3.9 5.8 18.6 7.5 10.5 3.6 7.8 4.9 8.7 2.9 15.6 3.5 2.1 13.9 0.0 3.6 6.1 4.4 4.9 3.6 1.4 4.0 15.7 6.1 7.1 2.8 ATL2 ARL6IP2 ENSG00000119787 "Atlastin GTPase 2" Q8NHH9 2 38293954-38377285 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029108, HPA075302" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Endoplasmic reticulum" "HPA029108: AB_10670557, HPA075302: AB_2732289" "unprognostic (5.80e-2)" "unprognostic (2.23e-1)" "unprognostic (3.57e-3)" "prognostic unfavorable (4.51e-4)" "unprognostic (3.64e-2)" "unprognostic (1.18e-1)" "unprognostic (9.10e-2)" "unprognostic (1.42e-2)" "unprognostic (9.81e-3)" "unprognostic (1.09e-2)" "unprognostic (1.27e-3)" "unprognostic (8.22e-2)" "unprognostic (6.86e-2)" "unprognostic (4.28e-2)" "unprognostic (2.09e-1)" "unprognostic (6.33e-2)" "unprognostic (1.84e-1)" 19.1 32.4 15.0 16.9 20.4 32.5 41.6 26.6 18.0 29.1 16.8 52.5 33.7 33.4 19.5 41.9 29.5 18.5 16.7 17.1 14.2 28.1 40.2 22.9 19.2 13.5 13.6 37.0 15.7 15.8 13.5 16.8 12.0 31.4 26.7 25.4 51.8 31.2 53.7 50.0 31.4 36.0 11.2 20.3 31.7 17.9 16.3 27.9 54.9 46.2 35.1 27.4 33.2 14.7 84.3 36.0 51.0 37.2 44.8 27.9 61.1 31.5 25.0 33.9 38.7 40.8 65.2 61.6 33.7 20.2 47.4 94.8 64.7 32.2 56.4 74.5 44.7 38.9 26.6 58.7 24.5 47.1 35.8 20.3 68.6 32.7 45.2 21.7 34.6 23.5 60.3 37.5 28.7 31.1 56.0 46.1 64.1 89.5 22.4 46.9 50.4 45.4 25.9 43.6 26.1 44.2 32.0 40.3 38.2 39.0 22.1 28.7 21.9 34.8 52.4 33.2 57.8 48.8 48.3 79.0 23.4 47.9 42.7 1.3 2.7 10.6 2.3 2.1 3.8 2.8 2.7 2.7 3.4 4.3 4.1 3.3 3.3 2.5 3.8 2.0 3.6 2.4 15.0 20.4 26.6 18.0 17.1 14.2 13.5 13.6 12.0 11.2 16.3 14.7 18.5 12.8 32.4 62.7 18.7 36.8 32.5 25.9 14.8 20.6 40.8 33.8 7.6 11.5 44.8 7.3 14.6 15.7 14.9 12.0 7.9 11.7 22.1 12.3 17.4 17.0 6.6 22.9 66.3 5.0 14.7 16.5 11.7 17.8 4.5 14.3 14.3 34.4 10.8 21.9 55.5 11.7 77.3 8.5 16.1 19.5 14.3 12.9 12.4 59.0 8.2 8.6 7.2 46.3 20.4 5.7 8.7 16.6 13.1 23.9 17.8 12.6 23.5 21.1 32.9 16.9 19.4 16.7 21.3 46.4 46.9 14.6 13.6 9.0 12.7 31.3 ATL3 DKFZP564J0863 ENSG00000184743 "Atlastin GTPase 3" Q6DD88 11 63624087-63671921 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Hydrolase "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Early spermatids: 264.4;Late spermatids: 728.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065702, HPA076616" Enhanced "Endoplasmic reticulum" NA NA 58000 "Cluster 39: Non-specific - mRNA processing" "Cluster 71: Testis - DNA repair" "Cluster 20: HeLa - Mitochondria" "Cluster 34: Spermatids - Unknown function" "Endoplasmic reticulum" "HPA065702: AB_2685536, HPA076616: AB_2732318" "unprognostic (4.19e-2)" "unprognostic (1.10e-1)" "unprognostic (8.32e-2)" "unprognostic (1.62e-1)" "unprognostic (6.89e-2)" "unprognostic (6.95e-2)" "unprognostic (1.91e-2)" "unprognostic (6.09e-3)" "unprognostic (3.38e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (1.04e-4)" "unprognostic (4.52e-2)" "unprognostic (1.11e-3)" "unprognostic (7.41e-2)" "unprognostic (2.88e-1)" "unprognostic (1.04e-1)" "unprognostic (7.67e-3)" 30.6 18.1 11.6 17.9 16.6 13.2 22.1 14.9 12.6 23.0 22.0 26.0 9.9 24.3 16.5 24.5 20.1 15.9 11.5 9.8 13.9 12.6 17.7 18.8 12.6 19.8 16.4 16.9 15.4 13.3 6.6 14.9 18.9 16.7 16.6 4.0 15.4 20.4 6.3 25.2 13.7 33.2 16.8 16.9 17.4 36.9 15.5 10.8 20.9 9.6 15.4 27.1 19.4 20.6 44.2 39.4 11.7 28.4 59.2 82.5 0.2 53.2 60.0 51.9 35.0 32.9 69.7 26.3 53.8 93.6 40.0 28.3 21.8 34.8 69.8 40.4 5.8 27.9 41.8 0.2 40.7 53.2 39.2 54.0 55.6 69.1 42.8 34.7 56.3 28.5 30.6 70.2 59.6 46.6 19.2 30.7 14.9 14.1 33.7 40.7 29.3 37.8 41.2 29.7 6.3 17.0 174.3 37.6 50.5 14.5 65.7 19.1 79.1 109.0 51.9 105.3 38.3 19.0 29.6 51.4 57.7 33.6 67.1 7.1 8.3 3.7 8.9 11.4 9.8 5.3 7.4 7.3 8.6 4.2 5.9 8.2 3.5 6.9 13.4 4.3 9.3 7.8 11.6 16.6 14.9 12.6 9.8 13.9 19.8 16.4 18.9 16.8 15.5 20.6 56.7 44.8 27.2 16.6 18.8 43.7 45.7 36.4 30.1 4.8 31.9 18.4 8.5 30.0 29.9 33.1 0.0 6.7 28.5 45.2 1.9 41.2 264.4 23.8 46.4 48.2 10.7 29.5 13.5 50.2 20.1 46.2 19.4 63.8 17.1 20.3 49.6 51.3 37.6 5.0 12.1 21.0 28.5 55.3 43.0 728.4 54.3 35.7 42.7 16.9 49.5 12.6 24.7 16.6 35.6 72.7 24.7 67.4 21.0 55.3 27.7 24.7 21.5 8.5 72.3 35.9 55.2 36.0 29.0 32.9 40.6 4.0 28.2 25.6 19.8 50.9 ATP2A1 "ATP2A, SERCA1" ENSG00000196296 "ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1" O14983 16 28878405-28904466 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" Translocase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 85 "skeletal muscle: 8241.7;tongue: 3199.6" "Cell type enriched" "Detected in some" 4 "Skeletal myocytes: 65.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.7" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "NK-cell: 1.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEK 293: 30.0" "Region enriched" "Detected in some" 8 "thalamus: 13.1" "Group enriched" "Detected in some" 6 "basal ganglia: 1.3;cerebral cortex: 1.4;hippocampal formation: 1.2" "CAB002310, CAB032706" Enhanced Approved "Endoplasmic reticulum" NA NA 2800000 "Cluster 15: NK-cells - Transcription" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 37: Myocytes - Muscle contraction" "Endoplasmic reticulum" "CAB002310: AB_564139, CAB032706: AB_2061286" "unprognostic (2.37e-1)" "unprognostic (6.81e-2)" "unprognostic (2.23e-5)" "unprognostic (5.35e-2)" "unprognostic (2.27e-1)" "unprognostic (2.04e-1)" "unprognostic (1.89e-1)" "unprognostic (1.19e-1)" "unprognostic (5.24e-2)" "unprognostic (1.87e-1)" "unprognostic (5.22e-2)" "unprognostic (4.94e-2)" "unprognostic (2.72e-4)" "unprognostic (1.70e-2)" "unprognostic (1.91e-1)" "unprognostic (1.49e-1)" "unprognostic (2.51e-2)" 1.5 1.1 0.7 1.6 0.8 1.9 1.8 0.9 2.6 1.0 0.1 1.4 1.6 1.5 0.4 27.7 1.4 0.5 1.2 0.6 0.8 1.3 3.1 1.2 2.9 1.1 0.7 1.6 1.0 0.5 3.2 0.7 1.5 9.5 0.4 7.9 67.2 3.5 8241.7 2.4 2.2 0.4 0.7 1.5 1.1 10.7 1.1 1.5 2.2 3199.6 0.4 1.2 1.2 1.4 7.7 8.0 14.4 8.7 0.7 2.3 13.3 3.5 2.0 0.6 0.6 4.5 6.7 11.9 4.1 0.6 4.8 7.9 3.6 0.2 1.0 5.9 30.0 4.2 19.0 14.4 0.3 1.8 3.8 5.9 1.6 0.9 0.7 7.3 0.4 21.8 8.2 9.8 0.4 15.2 17.3 9.5 14.4 2.8 11.2 26.4 10.2 9.1 0.1 0.9 9.2 7.3 5.0 6.8 5.2 5.2 5.1 4.2 3.1 4.5 9.4 8.5 4.5 14.2 9.5 12.0 8.7 23.4 4.4 0.0 0.0 0.2 0.3 0.0 0.4 0.5 0.3 0.3 0.0 0.2 0.4 0.4 0.0 1.6 0.0 1.0 0.5 0.2 0.7 0.8 0.9 2.6 0.6 0.8 1.1 0.7 1.5 0.7 1.1 1.4 0.3 0.0 0.0 0.7 0.2 0.1 0.0 0.3 0.6 2.1 0.5 0.5 0.5 0.0 0.2 0.0 14.6 0.4 0.0 0.6 0.0 0.1 1.3 0.4 0.4 0.3 0.0 0.0 2.3 0.2 0.2 0.5 1.5 0.7 0.0 0.7 0.0 0.6 0.1 0.0 2.3 0.3 0.0 0.6 0.0 3.9 0.3 0.3 0.0 1.0 0.0 0.3 0.0 0.5 2.3 0.2 1.2 0.0 0.1 0.2 0.7 0.1 0.4 4.7 0.0 65.2 0.6 5.7 3.4 0.3 0.1 0.7 0.4 0.7 0.6 0.1 AVL9 KIAA0241 ENSG00000105778 "AVL9 cell migration associated" Q8NBF6 7 32495426-32588726 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 93.9;Inhibitory neurons: 92.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050957 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 45: Intestine - Brush border" "Cluster 21: OE19 - Mitochondria" "Cluster 52: Non-specific - Transcription" "Endoplasmic reticulum" "HPA050957: AB_2681289" "unprognostic (2.33e-2)" "unprognostic (8.75e-3)" "unprognostic (3.45e-2)" "unprognostic (1.94e-1)" "unprognostic (8.07e-2)" "unprognostic (5.72e-3)" "unprognostic (5.14e-3)" "unprognostic (4.08e-2)" "unprognostic (1.46e-1)" "unprognostic (1.66e-1)" "unprognostic (4.21e-2)" "unprognostic (9.03e-2)" "unprognostic (1.68e-2)" "unprognostic (3.68e-2)" "unprognostic (9.22e-2)" "unprognostic (4.40e-2)" "unprognostic (1.05e-1)" 7.5 9.0 9.3 10.2 11.4 9.4 10.7 8.6 10.2 9.0 9.2 15.9 13.3 8.2 12.2 8.0 8.5 7.6 5.2 12.0 10.1 10.5 8.3 8.0 10.6 7.6 8.6 8.2 11.0 9.3 7.0 10.8 9.1 9.5 17.9 22.4 9.2 7.1 8.0 7.6 13.3 8.3 5.4 8.6 12.2 7.0 11.8 12.7 13.2 6.2 11.3 9.1 7.0 9.2 19.6 17.0 17.4 23.6 10.3 14.8 12.1 17.3 22.8 16.7 22.3 13.4 25.8 24.7 0.3 15.3 64.4 15.8 16.7 17.1 28.1 10.8 10.3 18.5 11.8 14.6 37.8 31.8 23.3 16.1 16.5 21.4 24.3 18.5 25.0 19.6 45.9 22.1 52.9 20.2 12.9 26.5 19.6 27.1 14.8 12.4 19.3 18.9 17.8 32.7 37.4 23.8 14.6 35.5 15.4 23.2 25.4 28.8 19.2 17.3 20.2 13.8 15.2 50.6 47.4 38.8 34.2 29.5 38.6 21.0 15.0 23.3 13.8 11.8 11.7 12.9 11.5 13.1 11.5 16.0 14.1 12.8 37.9 7.0 11.5 13.6 11.5 16.2 9.3 11.4 8.6 10.2 12.0 10.1 7.6 8.6 9.1 5.4 11.8 9.2 11.0 6.4 11.7 85.5 23.8 11.5 12.4 12.4 13.6 31.6 16.2 8.1 9.5 15.7 15.2 12.9 62.6 16.2 21.4 46.7 3.9 12.8 5.8 14.9 11.6 13.1 22.3 9.0 93.9 17.2 15.7 11.1 28.5 19.4 17.7 25.5 16.8 13.4 15.1 32.0 92.6 27.6 6.1 24.6 14.2 2.8 10.2 17.8 12.4 78.7 18.3 12.5 19.6 56.8 88.6 24.5 24.8 9.4 22.3 21.1 22.5 15.8 18.4 36.8 6.6 9.7 12.7 9.9 8.4 12.2 10.5 17.5 16.6 15.7 29.0 23.3 BCAP31 "6C6-Ag, BAP31, CDM, DXS1357E" ENSG00000185825 "B cell receptor associated protein 31" P51572 X 153700492-153724565 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Apoptosis, ER-Golgi transport, Host-virus interaction, Protein transport, Transport" "Deafness, Dystonia, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003906, CAB015350, CAB015424" Supported Approved Enhanced "Endoplasmic reticulum" NA NA 170000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 47: Cytotrophoblasts - Unknown function" "Endoplasmic reticulum" "CAB015350: AB_2243544, CAB015424: AB_781567, HPA003906: AB_1078270" "unprognostic (1.02e-2)" "unprognostic (2.14e-2)" "unprognostic (1.19e-2)" "unprognostic (3.70e-1)" "unprognostic (2.36e-2)" "prognostic unfavorable (9.87e-4)" "unprognostic (3.25e-3)" "unprognostic (4.20e-2)" "unprognostic (1.27e-1)" "unprognostic (5.75e-2)" "unprognostic (1.38e-1)" "unprognostic (1.10e-1)" "unprognostic (2.11e-1)" "unprognostic (1.28e-2)" "unprognostic (8.61e-2)" "unprognostic (2.33e-1)" "unprognostic (1.02e-1)" 294.1 213.9 171.5 100.9 175.5 151.3 210.9 171.8 213.9 139.5 202.5 157.7 133.3 127.4 228.9 214.0 151.0 118.0 123.5 183.0 192.1 160.7 185.5 144.5 111.8 190.8 187.5 130.9 266.4 193.7 123.5 143.3 195.3 154.6 166.5 63.9 179.7 177.7 81.9 187.3 143.8 155.0 183.4 138.5 129.3 117.3 186.9 99.7 161.4 75.5 134.6 177.9 145.8 185.0 505.5 482.4 128.0 650.6 593.8 179.1 295.3 269.9 287.5 291.6 371.6 386.8 361.9 315.9 1068.1 412.2 373.9 506.8 337.3 518.6 221.0 152.8 436.9 198.4 350.4 323.3 276.4 335.1 373.2 233.8 454.2 282.3 330.1 298.4 372.6 172.0 268.0 528.3 332.7 535.3 187.3 402.5 145.8 704.6 431.7 207.5 152.8 693.2 459.3 546.8 173.3 241.8 111.8 520.6 350.0 200.3 196.2 320.2 380.0 248.9 234.7 338.9 495.1 518.0 1120.1 397.3 460.9 402.6 223.7 630.5 484.2 489.1 507.5 535.7 454.7 436.1 504.5 507.4 420.7 463.6 439.1 474.7 624.5 449.8 632.3 666.9 457.1 1110.8 171.5 175.5 171.8 213.9 183.0 192.1 190.8 187.5 195.3 183.4 186.9 185.0 184.9 112.2 114.1 14.7 97.5 141.9 232.2 374.0 172.4 53.0 127.3 165.7 60.3 134.4 222.8 128.8 45.9 467.5 113.5 194.1 37.2 252.4 7.8 99.7 70.1 165.5 103.2 59.3 16.9 210.0 444.8 103.6 78.5 103.9 95.6 68.5 199.6 216.0 356.2 32.0 12.8 155.1 244.1 148.4 125.6 20.6 105.3 166.2 160.1 17.8 137.5 138.2 111.2 11.6 12.9 247.1 187.4 98.9 120.8 191.8 242.8 170.9 172.6 51.8 157.8 42.9 106.5 310.3 231.3 174.0 130.4 538.1 114.6 120.4 187.0 260.4 BNIP1 "Nip1, SEC20" ENSG00000113734 "BCL2 interacting protein 1" Q12981 5 173144442-173164387 "Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, ER-Golgi transport, Host-virus interaction, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008009, HPA008149" Supported Supported "Endoplasmic reticulum" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "HPA008009: AB_1078291, HPA008149: AB_2667993" "unprognostic (2.11e-1)" "unprognostic (1.72e-1)" "unprognostic (5.89e-2)" "unprognostic (3.08e-1)" "unprognostic (2.57e-1)" "unprognostic (2.94e-2)" "unprognostic (2.71e-2)" "unprognostic (1.50e-1)" "unprognostic (7.38e-2)" "unprognostic (2.70e-2)" "unprognostic (1.84e-2)" "unprognostic (2.28e-1)" "unprognostic (4.40e-3)" "unprognostic (2.10e-1)" "unprognostic (2.13e-1)" "unprognostic (5.61e-2)" "unprognostic (3.07e-2)" 9.5 13.0 14.2 6.6 14.2 34.2 11.3 14.5 16.6 8.3 13.3 9.6 8.7 8.3 12.0 10.2 8.9 7.7 11.6 14.2 15.6 12.4 12.6 8.9 10.3 14.9 14.9 8.6 19.3 10.9 12.3 11.3 15.1 9.1 11.0 12.3 8.8 7.0 13.5 8.8 7.9 9.1 14.0 10.1 10.7 14.9 15.3 11.9 10.9 15.8 9.7 10.3 7.8 15.1 18.2 15.9 18.6 23.2 11.2 26.1 20.7 15.0 23.5 31.4 31.3 27.6 24.3 19.4 17.3 22.5 32.7 14.0 24.4 42.6 31.7 31.8 19.5 17.4 10.6 14.6 29.7 28.1 20.9 14.7 21.1 29.0 36.3 14.8 24.2 27.8 17.1 22.8 25.8 42.3 31.3 24.7 8.2 22.0 18.8 20.4 15.0 23.8 18.0 10.9 23.5 14.6 13.3 16.7 33.5 12.9 28.3 22.1 19.4 26.8 20.0 23.4 30.7 17.3 21.8 30.1 24.8 28.5 17.8 0.1 10.1 4.4 16.9 11.4 14.2 10.5 14.5 12.2 12.6 11.6 12.1 11.9 0.4 11.9 9.8 15.6 14.0 10.1 14.2 14.2 14.5 16.6 14.2 15.6 14.9 14.9 15.1 14.0 15.3 15.1 9.3 3.2 11.4 2.9 10.9 11.6 10.0 13.4 5.2 13.5 9.4 9.5 5.8 7.2 9.7 5.5 4.2 24.2 15.4 7.4 27.4 14.7 3.4 11.5 11.6 9.1 7.2 2.5 3.9 12.3 20.2 9.0 10.7 14.0 1.3 12.6 6.1 6.7 15.6 10.1 4.7 13.7 2.0 7.1 4.9 6.6 8.7 7.9 3.6 4.7 10.1 12.4 13.4 5.5 8.3 8.8 7.4 11.7 10.8 12.4 9.5 15.7 9.8 11.2 0.0 6.1 9.0 32.4 11.3 10.8 10.9 30.1 11.5 14.0 11.5 9.4 C16orf95 ENSG00000260456 "Chromosome 16 open reading frame 95" Q9H693 16 87083562-87317420 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 15 "testis: 101.4" "Group enriched" "Detected in many" 4 "Early spermatids: 94.6;Late spermatids: 96.2;Spermatocytes: 127.9" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "HPA040850, HPA067924" Supported Approved "Endoplasmic reticulum" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 74: Testis - Spermatogenesis" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Endoplasmic reticulum" "HPA040850: AB_10794882, HPA067924: AB_2685924" "unprognostic (3.51e-1)" "unprognostic (1.95e-1)" "unprognostic (1.77e-2)" "unprognostic (4.30e-2)" "unprognostic (3.92e-2)" "unprognostic (4.60e-2)" "unprognostic (1.13e-1)" "unprognostic (2.45e-1)" "unprognostic (1.97e-2)" "unprognostic (1.09e-1)" "unprognostic (6.71e-2)" "unprognostic (1.79e-1)" "unprognostic (2.02e-1)" "unprognostic (1.48e-1)" "unprognostic (1.23e-1)" "unprognostic (1.61e-2)" "unprognostic (1.23e-1)" 2.5 3.8 2.2 1.2 2.2 3.3 2.2 2.5 3.3 1.1 1.7 1.6 1.4 1.2 0.4 1.5 1.2 0.9 2.6 2.2 2.2 2.7 6.9 1.3 1.3 2.1 2.3 1.5 3.2 1.3 2.2 0.4 2.4 1.2 0.8 0.6 1.5 0.6 4.3 1.2 1.5 0.4 2.2 1.6 2.2 101.4 2.5 1.7 1.2 3.1 0.8 1.4 1.2 2.0 3.4 9.2 3.2 3.9 3.7 2.1 5.4 3.1 1.3 3.0 2.3 4.4 5.4 8.3 8.6 0.6 3.3 2.7 3.0 2.1 1.4 4.2 5.4 7.9 3.5 6.5 3.2 0.9 1.5 3.7 0.7 3.5 1.1 1.5 2.9 6.1 7.2 4.2 3.6 8.7 3.0 7.4 3.0 2.1 5.5 6.7 1.4 4.8 1.9 1.4 4.0 3.3 7.6 0.4 2.5 1.1 4.5 4.2 3.3 5.5 2.3 3.3 3.0 12.5 10.9 16.2 7.4 8.0 3.8 0.0 2.5 0.6 2.6 2.7 1.8 1.7 2.1 2.3 2.4 1.4 1.7 2.9 0.4 0.7 3.4 3.3 2.9 1.8 2.2 2.2 2.5 3.3 2.2 2.2 2.1 2.3 2.4 2.2 2.5 2.0 1.9 0.0 1.5 1.0 1.9 1.7 0.5 0.6 6.2 2.5 2.0 2.9 2.4 1.5 0.3 0.0 2.1 2.6 0.4 6.0 1.9 2.8 94.6 0.5 0.4 1.3 0.0 6.9 1.5 3.4 3.4 1.3 4.1 0.4 0.0 0.7 2.2 5.9 2.9 1.7 1.5 3.4 0.0 1.6 1.8 96.2 3.4 0.9 0.0 1.9 2.7 3.7 2.1 1.0 1.8 4.0 2.4 5.3 6.4 0.6 6.4 3.4 1.0 2.2 26.3 0.4 1.8 127.9 8.0 3.0 0.6 1.1 1.1 0.6 5.3 0.4 C22orf39 MGC74441 ENSG00000242259 "Chromosome 22 open reading frame 39" Q6P5X5 22 19351368-19447711 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 118.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073701 Approved "Endoplasmic reticulum" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" "Endoplasmic reticulum" "HPA073701: AB_2686627" "unprognostic (4.97e-2)" "unprognostic (2.67e-2)" "unprognostic (1.87e-1)" "prognostic favorable (2.16e-4)" "unprognostic (1.27e-2)" "unprognostic (6.53e-2)" "unprognostic (5.07e-2)" "unprognostic (1.95e-3)" "unprognostic (8.93e-2)" "unprognostic (1.51e-2)" "unprognostic (1.45e-3)" "unprognostic (5.34e-3)" "prognostic favorable (1.44e-4)" "unprognostic (6.51e-2)" "unprognostic (2.92e-1)" "unprognostic (1.32e-2)" "unprognostic (5.32e-2)" 25.2 22.9 35.2 8.9 34.3 13.7 22.0 34.7 49.6 22.0 33.8 38.1 10.5 22.2 11.2 15.4 22.3 7.7 47.2 34.2 33.2 26.5 18.0 17.8 12.8 35.6 34.8 19.8 26.3 22.6 24.3 10.4 36.3 26.2 11.8 23.9 16.4 13.6 118.6 19.3 19.7 11.3 35.0 21.0 23.5 16.7 35.9 16.2 27.9 44.8 12.4 26.9 17.8 34.4 20.7 7.1 16.3 11.5 17.5 15.4 12.1 5.9 5.7 13.7 15.8 11.3 4.8 15.8 6.8 6.4 8.2 17.3 16.3 10.9 14.7 17.3 66.7 20.1 19.2 26.5 17.1 30.8 19.5 12.9 17.6 7.3 19.9 14.7 14.0 33.6 60.6 21.5 9.0 10.1 24.0 27.3 7.2 42.4 18.2 25.8 23.9 11.5 18.4 12.1 24.8 12.4 11.8 8.3 23.9 14.9 11.4 18.4 13.4 9.9 18.6 7.0 9.1 29.4 12.6 22.8 11.6 14.7 9.4 36.4 29.6 72.0 23.0 33.8 21.9 27.8 25.7 19.7 26.1 27.9 25.9 21.4 43.0 31.1 30.3 38.8 35.3 26.7 35.2 34.3 34.7 49.6 34.2 33.2 35.6 34.8 36.3 35.0 35.9 34.4 41.6 22.4 40.4 10.1 39.5 24.3 28.4 58.8 23.3 28.7 42.8 44.3 94.1 27.1 50.8 36.8 16.7 54.6 50.8 44.3 107.6 40.4 21.5 36.0 20.8 29.7 45.1 41.2 13.9 77.9 47.9 31.2 35.7 26.4 26.6 25.9 36.0 35.3 65.4 18.5 17.3 44.4 52.9 38.0 33.5 12.7 35.1 32.8 39.2 5.6 59.6 52.3 60.8 10.1 14.5 58.7 42.0 33.8 37.6 34.6 69.0 67.2 46.1 20.4 46.0 31.9 36.9 54.8 57.6 37.8 32.5 50.3 34.9 33.1 55.9 31.2 C2orf76 "AIM29, LOC130355, MGC104437" ENSG00000186132 "Chromosome 2 open reading frame 76" Q3KRA6 2 119302225-119366834 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 78.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044977, HPA055362" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 39: Non-specific - Basic cellular processes" "Endoplasmic reticulum" "HPA044977: AB_10961918, HPA055362: AB_2682794" "unprognostic (4.29e-1)" "unprognostic (2.07e-1)" "unprognostic (5.40e-3)" "unprognostic (1.04e-1)" "unprognostic (1.16e-2)" "unprognostic (2.20e-2)" "unprognostic (1.47e-3)" "unprognostic (5.51e-2)" "unprognostic (3.26e-3)" "unprognostic (1.16e-1)" "unprognostic (4.77e-2)" "unprognostic (1.14e-1)" "prognostic unfavorable (2.16e-8)" "unprognostic (3.42e-2)" "unprognostic (2.91e-2)" "unprognostic (7.55e-2)" "unprognostic (9.19e-2)" 20.2 19.7 23.2 10.2 23.3 10.0 22.4 23.8 29.5 13.0 21.3 12.3 6.9 17.1 43.4 16.2 20.5 12.6 16.1 22.2 23.5 19.9 14.1 9.9 15.2 24.3 23.2 17.8 15.7 20.6 10.7 11.3 24.4 16.0 11.7 9.4 16.0 15.4 10.3 20.6 7.6 16.7 24.2 10.9 11.3 19.3 23.0 13.5 20.5 14.5 14.0 13.9 10.9 26.6 17.0 15.7 22.4 14.3 31.7 38.3 12.8 23.4 16.7 15.0 16.3 10.1 11.3 20.7 40.6 24.7 17.4 7.8 10.1 14.9 15.0 17.7 33.5 39.1 11.7 13.5 21.8 15.0 24.6 20.4 25.3 21.3 13.8 19.3 21.7 15.7 12.6 19.6 22.5 25.7 15.7 28.5 12.4 13.3 12.4 9.6 4.7 29.1 33.9 18.0 14.8 16.7 17.0 24.1 33.7 21.0 13.2 52.5 20.3 17.4 13.5 14.6 12.7 12.8 22.5 22.1 17.5 11.1 20.0 29.1 20.9 21.9 19.9 20.2 18.0 20.0 15.2 18.3 21.3 14.7 13.8 19.3 37.2 32.5 12.7 20.1 16.8 11.9 23.2 23.3 23.8 29.5 22.2 23.5 24.3 23.2 24.4 24.2 23.0 26.6 30.3 6.4 11.4 22.5 11.1 25.0 17.2 47.7 17.1 3.3 18.5 19.7 18.5 12.8 24.4 14.7 0.0 26.4 15.2 7.1 78.2 14.7 11.7 27.6 15.4 20.4 10.9 16.4 12.4 17.8 32.4 20.7 9.7 19.7 22.2 8.4 15.0 11.6 26.7 1.7 8.6 11.2 22.4 15.0 23.4 7.7 19.3 13.8 44.4 12.2 20.6 19.8 26.8 14.6 25.2 14.0 9.2 17.0 8.9 11.8 12.2 47.0 42.8 4.6 6.6 13.8 18.8 38.8 22.4 18.8 35.7 20.7 15.3 11.4 10.0 13.0 C4orf3 "ALN, HCVFTP1" ENSG00000164096 "Chromosome 4 open reading frame 3" Q8WVX3 4 119296419-119304445 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 1070.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026907 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Endoplasmic reticulum" "HPA026907: AB_10600760" "unprognostic (2.97e-1)" "unprognostic (4.68e-2)" "unprognostic (3.32e-1)" "unprognostic (6.85e-3)" "unprognostic (9.30e-2)" "unprognostic (7.15e-3)" "unprognostic (2.04e-1)" "unprognostic (8.85e-2)" "unprognostic (4.90e-2)" "unprognostic (7.11e-2)" "unprognostic (9.94e-3)" "unprognostic (1.84e-1)" "prognostic favorable (3.46e-4)" "unprognostic (8.32e-2)" "unprognostic (2.65e-1)" "unprognostic (3.90e-1)" "unprognostic (1.59e-1)" 80.0 67.8 96.4 54.1 107.1 34.1 69.4 103.1 148.1 123.2 83.3 80.2 60.5 79.7 77.9 268.2 68.9 65.1 107.8 90.1 99.6 97.9 110.8 70.3 61.3 107.9 104.9 85.5 51.5 55.5 56.6 60.3 106.4 71.8 43.6 74.7 89.6 69.8 79.6 89.3 67.3 70.6 109.6 63.1 49.6 39.8 109.2 64.8 71.4 59.7 56.8 75.9 150.2 112.8 116.8 13.7 58.4 49.8 107.1 97.0 34.1 59.3 31.6 35.3 62.6 15.6 44.5 95.9 36.6 87.3 31.0 24.8 29.6 54.1 61.8 57.1 21.3 40.9 33.5 67.9 35.9 64.7 42.8 96.4 64.5 30.0 14.4 120.6 52.8 29.1 33.8 50.4 137.6 41.8 50.9 64.0 24.2 60.7 20.9 32.9 62.6 27.3 53.5 32.2 38.4 54.8 46.4 58.5 43.2 56.9 32.6 37.5 55.7 80.3 34.6 52.5 21.4 51.3 59.8 37.2 156.7 36.7 40.9 257.8 110.0 145.4 85.1 132.6 92.9 126.7 109.6 101.5 95.1 104.8 120.4 114.4 239.4 109.6 128.0 131.6 112.9 157.1 96.4 107.1 103.1 148.1 90.1 99.6 107.9 104.9 106.4 109.6 109.2 112.8 213.2 157.0 150.5 11.4 211.3 315.5 292.0 809.1 132.1 79.1 198.4 191.9 544.4 158.7 456.3 222.5 25.0 321.5 228.9 117.0 383.5 288.5 38.1 272.5 148.7 245.6 68.4 78.6 22.2 179.1 403.9 215.0 46.4 134.3 186.1 108.0 234.9 446.4 317.4 153.1 21.6 170.2 408.9 303.5 298.4 31.0 167.4 244.9 199.3 16.9 423.9 233.4 253.3 6.6 16.3 207.6 196.8 215.5 239.0 392.5 500.1 1070.2 542.7 78.9 197.2 145.8 246.0 182.7 67.0 245.9 346.6 445.7 203.2 150.3 135.8 428.1 CACNA1A "APCA, CACNL1A4, Cav2.1, EA2, FHM, HPCA, MHP, MHP1, SCA6" ENSG00000141837 "Calcium voltage-gated channel subunit alpha1 A" O00555 19 13206442-13633025 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "brain: 99.3" "Group enriched" "Detected in many" 8 "Bipolar cells: 101.4;Enteroendocrine cells: 214.1;Excitatory neurons: 318.3;Horizontal cells: 249.0;Inhibitory neurons: 372.1;Oligodendrocyte precursor cells: 271.9" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in all" 4 "cerebellum: 99.3;cerebral cortex: 30.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "SCLC-21H: 45.1;U-87 MG: 23.9" "Low region specificity" "Detected in all" "HPA064258, HPA068138, HPA071902" Enhanced Supported Uncertain "Endoplasmic reticulum" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "HPA064258: AB_2685229, HPA068138: , HPA071902: " "unprognostic (1.09e-1)" "unprognostic (3.73e-3)" "unprognostic (2.27e-1)" "unprognostic (2.78e-4)" "unprognostic (4.00e-2)" "unprognostic (2.29e-3)" "unprognostic (5.47e-2)" "unprognostic (3.13e-1)" "unprognostic (2.86e-1)" "unprognostic (1.14e-2)" "prognostic favorable (4.32e-4)" "unprognostic (5.31e-3)" "unprognostic (5.03e-6)" "unprognostic (6.29e-2)" "unprognostic (1.59e-1)" "unprognostic (2.61e-2)" "unprognostic (6.25e-2)" 1.0 2.3 15.4 0.3 15.8 0.1 0.9 99.3 30.4 0.6 0.0 0.7 1.2 0.8 1.1 0.2 3.2 0.1 0.6 15.1 6.8 0.5 0.2 0.2 0.4 7.2 11.2 0.9 2.6 0.1 4.2 0.0 10.6 0.4 0.4 7.1 0.2 0.1 0.5 0.3 1.7 0.2 9.4 0.6 2.7 2.3 11.3 0.1 0.7 0.1 0.2 0.3 0.7 15.2 0.0 0.1 0.1 6.0 0.2 0.2 0.0 2.2 2.5 0.3 0.0 0.0 0.0 0.2 0.0 0.2 5.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 2.8 0.0 1.9 0.0 0.0 0.0 0.0 0.0 7.2 0.2 0.0 0.1 0.2 1.4 0.1 0.3 0.6 0.0 0.1 0.0 0.1 45.1 0.0 0.0 0.0 0.4 0.1 0.0 1.9 0.1 0.1 0.9 0.2 0.1 0.0 0.0 0.0 23.9 0.1 0.6 0.5 0.0 0.1 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.3 0.1 0.1 0.3 0.1 0.2 0.1 0.1 0.0 15.4 15.8 99.3 30.4 15.1 6.8 7.2 11.2 10.6 9.4 11.3 15.2 7.7 6.4 3.2 31.3 9.6 0.6 3.4 0.0 0.0 101.4 3.1 7.4 2.8 0.0 1.3 1.8 16.7 0.0 2.9 0.6 0.0 0.5 27.1 1.2 6.3 6.5 214.1 0.4 318.3 0.4 0.2 4.7 10.7 2.6 1.3 5.2 1.8 1.2 0.5 249.0 372.1 5.0 4.1 1.9 1.4 28.0 1.2 2.1 0.0 28.1 1.2 3.0 4.1 271.9 11.5 1.5 0.1 0.4 0.5 0.8 0.2 2.0 3.7 7.0 0.0 5.1 17.6 4.3 7.1 0.4 0.1 0.3 2.0 2.5 1.0 0.9 CALR "cC1qR, CRT, FLJ26680, RO, SSA" ENSG00000179218 Calreticulin P27797 19 12938578-12944489 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 1717.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001513, HPA002242, CAB019952, CAB079775" Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA 210000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 32: U-937 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "Endoplasmic reticulum" "CAB001513: , CAB019952: AB_2069792, CAB079775: AB_303403, HPA002242: AB_1078384" "unprognostic (1.49e-1)" "unprognostic (1.57e-1)" "unprognostic (8.46e-2)" "unprognostic (4.25e-2)" "unprognostic (9.44e-3)" "unprognostic (6.93e-2)" "unprognostic (2.47e-2)" "unprognostic (4.60e-2)" "unprognostic (2.61e-1)" "prognostic favorable (1.10e-4)" "unprognostic (2.07e-1)" "unprognostic (3.76e-1)" "prognostic unfavorable (1.11e-16)" "unprognostic (2.37e-1)" "unprognostic (1.96e-1)" "unprognostic (1.37e-1)" "unprognostic (5.27e-2)" 295.5 257.6 201.7 352.9 213.4 554.9 218.9 238.0 213.5 256.3 324.0 304.6 287.3 275.8 647.7 338.2 266.7 164.1 303.2 203.5 239.7 296.9 782.3 308.9 230.0 260.4 230.1 272.2 319.7 292.2 284.5 403.3 254.5 277.9 336.7 96.2 299.3 247.2 119.8 189.3 277.2 349.7 237.7 277.3 300.6 165.2 267.3 245.3 702.9 104.7 319.4 252.2 236.6 274.2 1681.4 673.6 832.5 1984.9 1110.8 861.5 724.6 2075.3 1160.8 839.6 1280.4 1044.2 1353.5 1087.2 1960.0 2528.4 1064.5 672.1 906.1 1476.5 800.7 730.0 588.1 894.3 689.0 1619.6 2667.5 3638.5 1171.8 946.8 638.7 1222.3 957.7 1472.5 1507.8 743.1 814.5 536.3 911.7 1222.3 1040.0 2511.9 808.7 952.0 970.1 777.0 770.8 1329.9 1138.3 846.9 312.4 668.4 1438.7 769.8 472.6 789.9 1014.4 1558.9 1460.6 1113.2 666.2 1533.6 938.3 644.3 569.7 985.8 1567.6 1616.3 1258.1 67.5 72.8 39.7 172.8 147.8 119.3 90.0 99.7 130.0 76.3 77.5 73.0 134.4 23.8 103.1 122.7 215.6 83.4 75.8 201.7 213.4 238.0 213.5 203.5 239.7 260.4 230.1 254.5 237.7 267.3 274.2 385.2 147.4 160.7 34.6 385.7 261.7 336.3 217.3 221.4 76.8 214.9 140.8 43.7 163.0 175.4 222.5 127.2 652.9 515.5 524.4 64.6 582.7 27.8 206.3 364.2 305.6 353.6 266.1 14.2 285.5 1717.5 422.5 289.5 348.2 207.4 341.6 312.7 612.4 789.3 35.3 23.8 595.1 93.6 208.8 433.2 30.6 318.7 378.4 213.5 31.9 229.9 316.5 360.5 28.6 31.1 410.2 462.8 311.1 1059.6 426.1 377.8 182.8 147.5 167.7 203.8 224.2 328.9 276.1 306.6 245.5 213.5 964.4 345.8 399.4 471.4 329.6 CALU ENSG00000128595 Calumenin O43852 7 128739292-128773400 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 504.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "fHDF/TERT166: 2467.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006018 Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA 21000000 "Cluster 27: Non-specific - Gene expression" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "Endoplasmic reticulum" "HPA006018: AB_1845934" "unprognostic (7.22e-3)" "unprognostic (1.16e-3)" "unprognostic (3.16e-1)" "unprognostic (8.86e-2)" "unprognostic (1.27e-1)" "unprognostic (9.52e-3)" "prognostic unfavorable (1.80e-4)" "unprognostic (1.05e-3)" "unprognostic (1.95e-1)" "unprognostic (1.38e-1)" "unprognostic (2.75e-3)" "unprognostic (2.31e-1)" "prognostic unfavorable (1.30e-11)" "unprognostic (3.80e-3)" "unprognostic (1.66e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (4.60e-5)" 115.8 56.6 20.6 137.9 22.7 22.8 66.2 22.8 28.5 133.5 54.7 97.5 37.6 113.6 61.1 60.4 57.1 92.7 236.9 24.5 23.5 45.1 74.2 68.5 38.8 24.1 22.2 54.8 52.6 85.0 28.8 211.8 24.2 113.0 81.3 19.6 67.7 150.1 82.1 29.9 40.0 328.4 22.3 47.5 62.5 39.8 33.2 31.0 77.1 117.1 45.2 160.1 48.2 26.6 257.8 207.4 486.6 152.7 1348.5 1229.5 270.9 1821.7 1378.1 577.5 770.7 238.6 388.3 100.0 351.5 2467.8 850.4 144.9 258.2 318.2 826.5 80.6 138.2 136.6 283.7 295.0 657.1 187.2 254.3 930.5 223.6 868.3 370.6 904.4 537.3 116.4 237.9 172.8 1131.8 141.0 130.2 95.5 305.2 247.0 197.3 122.9 333.3 164.5 243.5 132.7 44.3 238.2 595.4 481.5 753.1 932.2 106.2 145.6 799.8 1706.6 234.2 1350.8 754.6 306.8 385.7 224.8 1478.6 223.6 1857.2 21.7 38.8 23.5 28.3 41.4 27.9 23.7 19.5 22.0 33.4 16.6 17.1 20.0 4.5 26.2 35.7 32.9 23.4 31.2 20.6 22.7 22.8 28.5 24.5 23.5 24.1 22.2 24.2 22.3 33.2 26.6 67.3 22.4 38.5 25.5 29.9 81.3 68.1 82.0 31.3 28.2 51.7 42.7 247.0 25.8 62.7 25.8 18.8 116.8 25.0 14.4 17.6 69.5 11.4 37.5 186.3 104.0 19.7 42.3 37.7 60.5 504.7 198.8 37.2 72.8 59.6 62.6 113.2 54.2 136.9 28.6 47.0 55.9 22.4 58.9 70.7 9.3 100.3 44.6 120.9 27.2 26.3 32.4 21.6 31.2 32.2 71.5 11.4 118.8 140.9 110.6 12.6 17.7 57.2 12.8 59.2 64.9 162.8 27.1 41.9 30.9 76.9 243.0 30.9 69.7 26.1 90.5 CANX "CNX, IP90, P90" ENSG00000127022 Calnexin P27824 5 179678628-179731641 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 817.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-HME1: 528.3;SK-MEL-30: 790.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004738, HPA009433, HPA009696" Enhanced Enhanced "Endoplasmic reticulum" NA NA 13000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 25: Spermatids - Spermatogenesis" "Endoplasmic reticulum" "CAB004738: AB_626784, HPA009433: AB_1078380, HPA009696: AB_1078379" "unprognostic (6.56e-2)" "unprognostic (9.34e-3)" "prognostic favorable (1.38e-4)" "unprognostic (1.19e-1)" "unprognostic (7.86e-2)" "unprognostic (1.41e-2)" "unprognostic (4.66e-3)" "unprognostic (8.57e-2)" "unprognostic (4.34e-2)" "unprognostic (1.25e-2)" "unprognostic (2.17e-3)" "unprognostic (4.48e-2)" "unprognostic (2.28e-1)" "unprognostic (1.87e-1)" "unprognostic (7.12e-2)" "prognostic unfavorable (3.17e-4)" "unprognostic (2.15e-1)" 128.3 112.8 15.0 36.3 17.6 76.0 110.6 18.8 31.1 121.4 25.1 108.7 45.0 137.7 171.7 106.7 109.8 6.2 137.5 13.8 24.1 121.4 193.2 112.7 18.4 24.7 24.1 129.6 209.7 9.6 96.5 75.0 20.2 96.0 62.6 68.0 123.3 17.8 111.6 83.5 97.4 85.0 19.2 73.2 115.2 75.0 17.9 9.0 159.2 53.6 16.6 112.0 95.6 22.6 13.0 91.5 89.5 53.0 295.4 229.3 37.9 261.4 342.8 341.2 298.2 148.2 49.6 309.3 351.0 127.8 121.4 18.7 120.2 121.1 405.9 64.6 6.3 63.0 247.8 22.9 399.9 82.9 50.0 39.1 313.5 118.6 528.3 56.1 93.9 23.9 43.2 99.9 39.9 51.2 40.9 15.1 9.4 11.7 6.4 43.2 71.3 24.9 252.1 82.8 24.4 8.0 62.7 16.7 790.3 182.7 267.3 16.3 234.7 49.9 56.5 36.1 200.2 19.7 87.2 46.1 53.3 50.4 46.5 51.8 61.8 17.4 29.9 38.9 34.4 14.4 21.2 25.0 47.6 10.0 15.3 15.6 9.6 32.1 30.1 38.7 16.4 74.1 15.0 17.6 18.8 31.1 13.8 24.1 24.7 24.1 20.2 19.2 17.9 22.6 187.0 198.7 296.6 53.5 109.4 148.5 115.4 181.3 152.0 117.4 245.8 153.5 537.0 185.8 247.0 182.1 158.4 162.5 148.6 174.3 49.0 173.6 225.5 160.9 253.9 204.0 178.0 133.3 45.5 153.5 245.8 202.8 156.5 255.5 197.9 137.7 157.5 438.7 227.7 159.9 77.0 250.0 134.3 206.4 215.6 817.5 159.1 218.3 176.1 44.0 181.1 213.8 84.5 63.3 79.4 153.1 125.1 191.1 327.3 249.5 188.2 196.4 294.3 160.9 92.1 114.6 211.2 158.4 72.7 182.3 161.8 244.8 105.8 183.1 251.0 157.8 CCDC47 GK001 ENSG00000108588 "Coiled-coil domain containing 47" Q96A33 17 63745255-63776351 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Chaperone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029674, HPA072573, HPA075958" Approved Enhanced "Endoplasmic reticulum" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Endoplasmic reticulum" "HPA029674: AB_10602703, HPA072573: AB_2686535, HPA075958: " "unprognostic (6.33e-2)" "unprognostic (3.26e-2)" "prognostic favorable (2.17e-4)" "unprognostic (1.38e-1)" "unprognostic (3.54e-1)" "unprognostic (1.47e-2)" "unprognostic (1.53e-2)" "unprognostic (9.08e-2)" "unprognostic (1.57e-1)" "unprognostic (3.68e-1)" "unprognostic (2.73e-1)" "unprognostic (1.26e-1)" "unprognostic (8.35e-2)" "unprognostic (1.88e-1)" "unprognostic (6.43e-2)" "unprognostic (7.46e-2)" "unprognostic (1.16e-1)" 57.9 67.3 24.3 42.5 33.6 29.0 57.1 28.8 39.2 47.7 46.9 83.4 87.1 39.1 53.7 52.6 43.9 48.2 65.5 29.3 27.9 72.0 102.2 52.7 33.5 28.8 27.4 35.3 59.8 84.6 21.9 54.8 29.9 60.2 80.6 46.9 62.4 52.0 115.3 52.2 78.2 42.1 30.1 35.6 78.5 32.1 26.0 29.9 62.0 83.7 40.5 58.5 29.3 34.3 143.3 133.8 81.4 71.9 112.4 74.0 158.0 141.9 92.6 96.1 112.4 118.7 127.0 112.9 74.3 100.9 110.8 114.3 99.3 88.1 168.9 39.4 101.2 160.9 106.4 117.3 107.6 129.9 81.3 78.5 121.3 132.4 113.2 67.9 81.3 55.3 183.5 95.5 79.4 116.1 100.5 48.1 70.8 179.4 134.0 92.2 157.9 154.6 115.3 161.1 74.2 101.5 95.2 242.8 120.3 103.0 159.8 70.4 104.0 177.6 112.9 130.6 166.0 93.9 119.9 112.8 103.9 81.4 147.3 53.2 59.7 75.6 40.7 61.5 47.9 38.4 39.8 37.9 82.5 31.7 41.1 36.2 47.6 43.4 65.9 54.7 49.0 52.0 24.3 33.6 28.8 39.2 29.3 27.9 28.8 27.4 29.9 30.1 26.0 34.3 96.9 144.2 122.2 16.3 46.6 100.8 108.5 95.9 98.4 40.9 65.9 53.6 129.0 72.9 128.3 60.7 14.6 111.1 59.0 99.8 9.8 115.3 17.9 80.3 73.9 83.9 52.2 76.6 26.2 105.1 98.3 85.3 65.7 126.0 45.5 31.2 68.2 96.3 57.5 57.2 25.9 95.1 83.4 56.9 58.3 11.5 47.8 60.7 39.2 13.1 52.9 55.3 25.7 22.6 25.5 92.0 62.6 56.1 56.0 89.6 87.5 32.6 83.0 27.9 72.3 117.2 92.1 82.0 44.7 90.1 90.8 144.1 42.7 53.0 110.5 83.3 CCR10 GPR2 ENSG00000184451 "C-C motif chemokine receptor 10" P46092 17 42678889-42683917 "Cancer-related genes, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 20.2" "Cell type enhanced" "Detected in many" "B-cells: 14.1;Bipolar cells: 12.8;Plasma cells: 62.7;Sertoli cells: 19.7;Smooth muscle cells: 16.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "plasmacytoid DC: 24.7;T-reg: 72.4" "Group enriched" "Detected in many" 8 "dendritic cells: 24.7;T-cells: 72.4" "Cell line enhanced" "Detected in some" "Karpas-707: 8.4;RPMI-8226: 6.5;U-266/70: 17.1;U-266/84: 8.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB011684, HPA048007, HPA069188" Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "CAB011684: AB_731502, HPA048007: AB_2680232, HPA069188: AB_2686100" "unprognostic (3.25e-2)" "unprognostic (2.71e-2)" "unprognostic (5.70e-2)" "unprognostic (2.41e-2)" "unprognostic (5.25e-2)" "unprognostic (2.23e-3)" "unprognostic (5.18e-4)" "unprognostic (1.15e-1)" "unprognostic (9.55e-2)" "unprognostic (1.56e-1)" "unprognostic (1.21e-3)" "unprognostic (1.01e-2)" "unprognostic (2.32e-11)" "unprognostic (2.84e-2)" "unprognostic (1.53e-1)" "unprognostic (1.88e-2)" "unprognostic (1.87e-1)" 4.5 2.1 1.1 0.7 1.1 0.2 5.2 3.1 2.7 6.6 0.0 4.8 1.8 8.5 0.3 0.8 8.5 0.2 4.4 0.7 6.5 2.8 0.8 4.1 0.3 3.9 4.6 6.2 2.3 0.0 20.2 0.7 6.6 3.8 0.2 0.7 2.2 0.6 4.7 1.5 3.1 0.5 1.0 3.2 2.6 4.0 4.0 0.2 2.8 0.4 0.0 2.4 3.2 1.2 0.5 0.8 0.8 4.7 0.3 0.7 1.1 1.7 0.5 0.2 0.4 0.7 0.3 0.1 0.3 0.3 1.6 0.8 0.0 0.1 0.1 2.0 1.2 0.0 3.2 0.4 0.6 0.0 0.3 0.7 0.0 0.3 0.0 0.5 0.1 0.3 2.6 8.4 0.0 0.3 0.1 2.4 0.6 0.0 1.2 0.6 0.1 6.5 1.1 0.0 0.7 1.0 0.4 0.0 0.2 0.3 0.8 0.9 1.9 2.1 0.5 0.7 0.2 17.1 8.4 2.5 1.3 0.6 0.9 0.0 0.6 0.2 0.4 0.1 0.3 5.3 10.9 5.4 0.4 5.9 1.3 1.8 0.2 0.2 0.4 24.7 72.4 1.5 1.1 1.1 3.1 2.7 0.7 6.5 3.9 4.6 6.6 1.0 4.0 1.2 7.3 0.0 0.0 0.7 14.1 0.8 0.3 0.4 0.6 12.8 1.0 1.3 2.1 0.0 0.1 0.0 0.0 0.2 0.6 0.0 3.9 0.3 0.5 1.6 2.9 2.9 1.8 0.0 5.1 0.5 0.3 5.4 1.5 0.9 0.0 0.6 2.2 0.2 1.9 1.7 4.6 0.6 2.0 2.5 3.7 2.5 5.6 1.2 5.4 0.0 3.8 2.5 2.1 1.0 1.3 0.3 0.1 2.6 62.7 0.3 0.2 0.7 1.0 3.2 19.7 2.3 16.7 1.6 2.1 0.3 0.3 0.0 2.9 1.9 0.7 0.1 CD1D ENSG00000158473 "CD1d molecule" P15813 1 158178030-158186427 "Cancer-related genes, CD markers, Predicted membrane proteins" "Immunity, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 18.2;liver: 15.3;lymphoid tissue: 23.9" "Cell type enhanced" "Detected in many" "B-cells: 22.2;Kupffer cells: 54.6;Macrophages: 40.8;monocytes: 45.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "classical monocyte: 139.0;intermediate monocyte: 63.8;myeloid DC: 139.3" "Group enriched" "Detected in many" 8 "dendritic cells: 139.3;monocytes: 139.0" "Cell line enhanced" "Detected in some" "HHSteC: 10.2;JURKAT: 49.4;MOLT-4: 13.6;THP-1: 8.8" "Low region specificity" "Detected in all" "CAB016107, HPA072662" Enhanced Supported "Endoplasmic reticulum" NA NA 880000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Endoplasmic reticulum" "CAB016107: AB_626960, HPA072662: AB_2686545" "unprognostic (8.67e-2)" "unprognostic (6.99e-2)" "unprognostic (2.48e-1)" "unprognostic (1.48e-2)" "unprognostic (1.05e-1)" "unprognostic (1.42e-1)" "unprognostic (3.85e-1)" "unprognostic (9.67e-3)" "unprognostic (2.37e-1)" "unprognostic (3.52e-1)" "unprognostic (2.23e-2)" "unprognostic (4.46e-2)" "prognostic unfavorable (2.12e-5)" "unprognostic (9.31e-3)" "unprognostic (2.35e-1)" "unprognostic (2.32e-2)" "unprognostic (3.38e-1)" 2.7 2.0 0.1 7.5 0.2 3.1 2.0 0.1 0.4 1.5 0.7 4.4 7.4 2.2 0.5 0.8 2.1 1.8 3.3 0.1 0.2 2.2 15.3 3.4 4.7 0.3 0.2 0.6 1.9 0.3 1.0 0.4 0.3 2.2 2.9 0.3 1.1 0.7 1.1 0.3 18.2 2.3 0.1 23.9 2.3 2.5 0.2 9.4 2.7 0.6 3.0 1.8 1.0 0.4 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.3 0.0 0.0 3.5 0.0 6.0 0.0 0.0 0.1 0.2 0.0 0.0 10.2 0.1 0.0 3.9 0.6 0.0 0.7 0.0 0.0 49.4 0.0 0.0 0.0 0.0 13.6 1.4 0.6 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.2 0.0 0.0 0.0 0.0 0.1 0.0 8.8 0.0 0.0 2.0 0.0 0.0 0.3 0.0 0.3 0.0 3.7 0.4 0.2 139.0 0.4 0.2 63.8 0.5 17.6 0.1 0.1 139.3 13.4 0.1 0.0 7.2 0.3 11.0 1.4 0.2 80.7 0.1 0.2 0.1 0.4 0.1 0.2 0.3 0.2 0.3 0.1 0.2 0.4 9.4 0.0 3.6 0.0 22.2 0.3 0.5 0.8 0.6 0.7 0.1 0.9 0.7 2.8 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.4 5.6 0.4 2.0 2.4 2.4 1.7 0.0 0.0 0.2 0.5 0.0 0.3 1.3 0.1 3.3 6.3 11.3 1.7 0.2 2.0 0.0 54.6 0.8 2.1 0.0 40.8 0.0 0.0 45.4 0.6 1.0 0.0 0.0 0.0 6.4 0.0 3.7 0.1 7.3 0.1 0.0 0.3 0.0 1.2 0.4 1.0 2.1 0.0 0.1 0.1 0.6 0.1 4.5 0.1 CD3D T3D ENSG00000167286 "CD3d molecule" P04234 11 118339075-118342705 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 30 "lymphoid tissue: 906.7" "Group enriched" "Detected in many" 14 "dendritic cells: 231.0;T-cells: 665.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 52 "gdT-cell: 1462.4;MAIT T-cell: 990.0;memory CD4 T-cell: 1206.1;memory CD8 T-cell: 1368.7;naive CD4 T-cell: 1091.4;naive CD8 T-cell: 1338.9;T-reg: 1660.4" "Lineage enriched" "Detected in all" 66 "T-cells: 1660.4" "Group enriched" "Detected in some" 4 "JURKAT: 621.5;MOLT-4: 1299.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB013055, HPA071778" Enhanced Uncertain "Endoplasmic reticulum" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Endoplasmic reticulum" "CAB013055: , HPA071778: " "prognostic favorable (3.00e-4)" "prognostic favorable (8.46e-5)" "unprognostic (1.05e-2)" "prognostic favorable (1.73e-7)" "unprognostic (6.00e-2)" "prognostic favorable (1.70e-4)" "unprognostic (3.82e-1)" "unprognostic (2.40e-2)" "unprognostic (2.24e-3)" "unprognostic (1.01e-2)" "unprognostic (5.69e-2)" "unprognostic (2.55e-1)" "prognostic unfavorable (3.07e-5)" "unprognostic (9.00e-2)" "unprognostic (2.02e-1)" "unprognostic (3.66e-2)" "prognostic favorable (6.16e-4)" 4.1 3.8 0.3 77.5 0.4 28.6 9.9 0.4 1.4 5.2 0.7 18.8 21.7 3.6 5.7 7.6 4.5 15.7 3.7 0.3 0.6 2.3 7.9 20.6 222.7 1.1 0.4 3.2 1.3 0.9 0.8 1.2 0.6 5.9 22.4 0.3 8.3 3.1 2.5 4.0 30.1 3.9 0.7 60.9 23.8 2.4 0.5 906.7 3.8 1.4 166.9 26.7 3.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 621.5 49.8 0.0 0.0 0.0 1299.8 237.2 1.2 0.0 0.0 0.7 0.1 0.5 0.0 0.0 0.4 0.0 0.0 1.9 0.0 0.2 0.8 0.0 0.5 0.0 1.5 1.1 0.0 0.9 1.1 0.4 0.0 0.1 0.0 10.1 5.3 4.6 1462.4 3.3 990.0 9.6 1206.1 1368.7 5.0 3.7 1091.4 1338.9 25.1 4.2 5.3 6.0 1660.4 1138.7 0.3 0.4 0.4 1.4 0.3 0.6 1.1 0.4 0.6 0.7 0.5 0.8 5.9 6.4 29.6 0.0 18.6 15.3 0.3 0.0 1.8 0.0 5.4 6.7 2.8 7.2 2.6 3.7 0.0 0.4 231.0 0.9 0.0 1.3 0.4 0.8 0.8 5.0 1.2 16.8 0.0 0.0 0.0 8.3 21.4 0.9 12.6 0.0 7.9 3.1 0.6 0.0 0.0 0.2 0.0 14.9 28.4 0.7 0.0 14.2 12.4 1.0 25.0 0.0 32.0 0.0 0.0 0.1 0.2 0.0 21.0 0.3 0.0 3.4 1.5 0.0 0.0 2.5 5.8 0.1 1.2 1.4 11.8 0.3 665.7 0.0 1.1 0.2 CDS2 ENSG00000101290 "CDP-diacylglycerol synthase 2" O95674 20 5126879-5197887 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/84: 160.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019698 Approved Approved "Endoplasmic reticulum" No No "Cluster 38: Basophils - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 16: U-266 - Nucleosome" "Cluster 48: Smooth muscle cells - ECM organization" "Endoplasmic reticulum" "HPA019698: AB_1846464" "unprognostic (4.59e-2)" "unprognostic (1.98e-1)" "unprognostic (2.39e-1)" "unprognostic (3.37e-2)" "unprognostic (1.15e-1)" "unprognostic (1.99e-1)" "unprognostic (1.44e-1)" "unprognostic (3.22e-1)" "unprognostic (1.71e-2)" "unprognostic (1.48e-1)" "unprognostic (3.35e-3)" "unprognostic (1.65e-1)" "prognostic favorable (3.53e-9)" "unprognostic (8.89e-2)" "unprognostic (3.53e-1)" "unprognostic (1.38e-1)" "unprognostic (2.44e-1)" 14.3 13.8 30.0 9.1 32.4 13.0 10.6 22.9 28.6 10.5 2.1 13.0 5.2 11.5 8.2 9.2 10.7 8.9 24.8 30.3 34.6 14.6 12.8 13.4 8.8 27.2 36.1 9.3 6.5 17.3 14.4 9.9 37.4 13.4 10.7 31.5 7.6 16.7 9.7 5.9 10.1 18.0 18.8 9.4 10.6 11.7 42.5 13.3 12.5 12.7 12.6 10.8 7.7 21.7 25.4 27.4 28.1 13.7 16.4 14.9 11.7 13.9 28.5 22.7 32.2 17.8 23.8 19.8 6.8 26.4 41.1 36.5 23.1 29.5 23.9 18.4 6.8 23.5 7.9 27.0 15.3 13.9 8.1 12.8 16.1 29.8 11.5 20.3 30.7 26.5 11.6 23.9 21.4 4.6 30.1 5.7 12.1 12.4 7.6 25.0 22.5 9.4 14.5 25.0 11.4 15.5 15.3 26.2 34.6 33.8 16.4 6.7 25.4 15.6 11.6 14.1 14.0 20.8 160.2 15.9 7.4 11.7 8.1 55.3 17.3 21.2 15.2 14.7 16.6 12.1 15.6 17.3 13.8 11.4 12.0 11.8 49.7 12.0 13.4 10.9 19.5 23.7 30.0 32.4 22.9 28.6 30.3 34.6 27.2 36.1 37.4 18.8 42.5 21.7 43.3 19.2 15.7 36.9 36.2 17.6 30.3 33.0 14.2 60.1 17.7 14.4 55.2 18.6 19.6 33.1 95.9 22.2 29.6 15.3 5.9 33.1 71.6 20.1 14.0 42.3 10.7 14.9 39.3 22.7 40.0 17.9 15.3 21.5 21.0 20.5 27.8 21.7 60.8 43.7 52.0 12.4 12.2 36.6 26.1 33.3 16.1 31.5 32.0 21.5 38.7 21.9 28.8 28.6 56.1 31.7 20.3 24.8 48.9 23.1 15.7 13.2 23.5 65.5 19.7 19.7 52.1 26.8 34.7 14.8 15.3 16.3 36.7 13.0 13.1 29.1 CERS1 "LAG1, LASS1, UOG1" ENSG00000223802 "Ceramide synthase 1" P27544 19 18868545-18896727 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 298.6;choroid plexus: 92.2" "Cell type enriched" "Detected in some" 5 "Late spermatids: 126.6" "Group enriched" "Detected in many" 5 "glioma: 13.5;melanoma: 4.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 32.1;HEK 293: 34.7;NB-4: 39.3;NTERA-2: 25.2" HPA045724 Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" "Endoplasmic reticulum" "HPA045724: AB_10969762" "unprognostic (8.25e-2)" "unprognostic (8.91e-2)" "unprognostic (2.12e-2)" "unprognostic (2.14e-1)" "unprognostic (3.59e-2)" "unprognostic (6.47e-2)" "unprognostic (1.15e-2)" "unprognostic (1.13e-1)" "unprognostic (4.02e-1)" "unprognostic (7.04e-3)" "unprognostic (3.52e-3)" "unprognostic (1.92e-1)" "unprognostic (4.59e-2)" "unprognostic (2.99e-2)" "unprognostic (3.15e-2)" "unprognostic (9.15e-2)" "unprognostic (3.49e-1)" 0.9 3.1 206.4 0.8 244.8 0.2 0.6 256.1 216.6 2.1 92.2 3.5 0.1 0.7 0.5 1.0 0.7 2.5 4.3 218.8 200.4 0.8 0.2 0.5 0.0 298.6 233.8 2.8 0.9 2.9 12.8 0.3 240.9 1.4 0.2 4.8 0.9 0.5 21.3 0.6 1.0 1.5 247.7 0.2 1.2 29.3 251.3 0.3 1.0 12.3 0.1 1.7 1.7 248.3 0.2 3.3 19.1 32.1 1.1 0.4 0.8 2.2 0.1 5.4 3.9 15.7 1.2 0.1 22.0 1.4 4.4 0.3 13.8 0.6 2.1 0.0 34.7 0.2 0.7 11.7 2.4 3.4 0.5 1.2 0.2 1.7 0.6 6.0 1.3 0.2 2.2 0.2 3.7 8.4 0.3 39.3 25.2 0.1 0.7 0.2 0.6 0.7 4.1 0.0 17.8 15.8 0.8 0.1 14.1 6.0 5.5 20.5 0.5 0.1 4.3 3.4 4.8 0.7 0.5 0.1 0.2 1.2 12.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 206.4 244.8 256.1 216.6 218.8 200.4 298.6 233.8 240.9 247.7 251.3 248.3 0.2 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 3.6 0.6 1.3 0.6 0.0 0.0 0.0 2.1 0.0 0.1 0.2 0.0 0.0 21.1 0.3 0.4 0.6 0.0 0.0 0.0 0.2 0.0 1.0 0.0 1.1 0.0 1.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.4 126.6 1.2 0.2 1.8 0.0 0.0 10.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.1 0.0 1.6 0.0 1.0 0.4 1.4 2.9 0.0 0.4 0.3 0.1 0.4 0.0 0.0 CES1 "CEH, CES1A1, CES1A2, CES2, HMSE, HMSE1, SES1" ENSG00000198848 "Carboxylesterase 1" P23141 16 55802851-55833337 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "liver: 2517.1" "Group enriched" "Detected in many" 7 "Cholangiocytes: 613.4;Hepatocytes: 2420.8" "Cancer enriched" "Detected in all" 6 "liver cancer: 711.4" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 16 "classical monocyte: 109.6;myeloid DC: 114.5" "Group enriched" "Detected in many" 22 "dendritic cells: 114.5;monocytes: 109.6" "Group enriched" "Detected in some" 5 "Hep G2: 700.9;THP-1: 688.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA012023, HPA046717" Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" No NA 40000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Endoplasmic reticulum" "HPA012023: AB_1846554, HPA046717: AB_2679770" "unprognostic (1.04e-2)" "unprognostic (9.85e-2)" "unprognostic (2.94e-1)" "unprognostic (1.28e-1)" "unprognostic (1.55e-3)" "unprognostic (7.46e-3)" "unprognostic (1.51e-1)" "unprognostic (1.42e-1)" "unprognostic (3.51e-1)" "unprognostic (5.74e-2)" "unprognostic (4.62e-2)" "unprognostic (3.29e-2)" "unprognostic (1.91e-2)" "unprognostic (5.32e-2)" "unprognostic (1.92e-1)" "unprognostic (2.87e-1)" "prognostic unfavorable (9.92e-4)" 94.9 14.1 0.9 3.2 1.2 27.0 43.6 0.8 1.8 26.6 3.7 82.3 24.0 60.4 7.5 41.1 54.6 272.9 66.1 1.0 1.4 6.7 2517.1 167.8 1.8 2.3 1.2 20.3 8.8 0.7 3.7 8.5 1.5 39.2 12.3 2.9 41.4 36.4 5.2 14.0 27.4 40.4 1.0 41.0 56.1 7.8 1.1 2.5 9.9 9.4 1.0 57.7 17.7 1.1 0.7 4.4 0.0 0.0 90.8 0.6 3.1 0.3 0.0 0.0 0.0 43.5 0.0 0.0 19.4 0.0 1.4 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.9 700.9 0.0 1.3 0.1 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 40.8 0.1 0.6 0.0 0.0 1.5 6.7 0.0 0.5 0.0 0.1 3.2 0.1 1.1 0.9 0.0 688.0 0.1 0.0 0.4 0.2 0.5 2.2 0.1 1.0 0.0 151.7 0.0 0.0 109.6 0.5 4.5 6.1 1.5 1.1 0.7 5.0 114.5 1.2 0.7 1.1 0.6 0.3 1.6 6.8 0.4 58.0 0.9 1.2 0.8 1.8 1.0 1.4 2.3 1.2 1.5 1.0 1.1 1.1 2.0 16.0 67.6 0.0 11.3 16.7 5.3 6.8 1.2 0.0 1.2 8.1 0.8 613.4 31.5 16.5 0.0 0.5 12.2 0.1 0.0 15.4 79.6 1.0 10.6 8.9 37.5 177.7 0.0 18.7 2.2 57.4 1.1 0.2 6.3 0.0 66.0 2420.8 18.1 0.0 0.0 12.2 4.1 107.3 26.7 197.8 18.6 58.7 39.2 1.0 39.6 10.4 7.2 0.0 0.0 0.9 1.3 98.9 1.8 1.5 0.6 0.9 169.0 0.9 0.0 9.8 9.8 1.0 2.3 20.6 11.6 0.8 16.9 0.9 0.7 2.6 CHKA "CHK, CKI" ENSG00000110721 "Choline kinase alpha" P35790 11 68052859-68121444 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 179.6;Early spermatids: 357.3;Late spermatids: 267.3;Oligodendrocytes: 203.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 6.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "SK-MEL-30: 183.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024153, CAB072803" Approved Approved "Endoplasmic reticulum" NA Yes "Cluster 52: Eosinophils - Transcription" "Cluster 43: Testis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 34: Spermatids - Unknown function" "Endoplasmic reticulum" "CAB072803: , HPA024153: AB_1846664" "unprognostic (5.16e-2)" "unprognostic (1.46e-1)" "unprognostic (2.52e-1)" "unprognostic (2.51e-1)" "unprognostic (2.66e-1)" "unprognostic (2.81e-1)" "prognostic unfavorable (7.75e-4)" "unprognostic (2.36e-3)" "unprognostic (1.66e-3)" "unprognostic (1.67e-2)" "unprognostic (1.33e-1)" "unprognostic (1.99e-1)" "unprognostic (5.97e-3)" "unprognostic (5.00e-2)" "unprognostic (6.06e-2)" "unprognostic (1.82e-1)" "unprognostic (4.73e-2)" 17.0 35.8 49.4 7.1 54.2 33.8 20.9 51.8 57.8 18.3 53.5 25.8 21.6 12.2 20.5 6.2 13.2 10.3 14.5 49.5 50.7 23.9 43.3 17.8 9.0 56.6 53.6 20.1 38.0 8.0 21.6 5.2 61.5 31.0 12.8 21.1 44.9 16.4 8.3 8.7 23.1 5.4 51.0 30.0 40.0 75.5 54.0 5.7 43.6 4.5 5.5 19.4 9.3 71.7 25.6 21.3 24.2 24.1 8.0 6.1 24.5 7.7 13.6 22.5 14.4 92.2 70.5 18.9 27.4 12.4 23.2 16.2 34.4 5.6 18.5 8.7 12.1 23.8 29.6 106.9 22.9 25.6 12.5 11.0 9.4 10.0 4.8 12.3 12.7 11.9 23.1 34.7 12.0 19.4 14.6 68.4 40.1 83.2 14.2 21.3 26.1 54.6 18.1 27.3 17.9 19.6 14.9 74.6 183.8 19.9 31.6 34.4 7.3 14.2 16.3 32.4 10.4 37.0 42.5 34.4 14.6 32.8 13.0 0.0 0.8 6.1 0.1 1.5 0.0 0.7 0.1 0.2 0.9 0.3 0.4 0.2 0.4 1.1 0.9 0.7 0.2 0.2 49.4 54.2 51.8 57.8 49.5 50.7 56.6 53.6 61.5 51.0 54.0 71.7 27.2 44.8 36.6 179.6 10.1 15.8 16.6 6.5 18.2 10.6 49.4 35.7 3.6 35.8 20.2 3.7 33.3 8.2 14.2 48.1 13.7 9.6 357.3 42.7 16.2 13.6 28.1 6.7 89.0 19.3 3.4 9.2 37.2 59.0 19.0 23.4 11.7 19.8 17.6 57.2 63.2 16.3 0.0 28.5 19.4 267.3 6.2 31.0 23.2 59.0 8.5 21.4 2.1 100.0 203.5 18.4 18.0 2.6 10.1 17.3 21.6 4.6 23.1 28.4 0.0 9.6 9.8 121.9 20.7 9.2 10.4 13.0 8.2 16.9 31.7 39.2 CISD2 "ERIS, Miner1, NAF-1, WFS2, ZCD2" ENSG00000145354 "CDGSH iron sulfur domain 2" Q8N5K1 4 102868974-102892807 "Disease related genes, Human disease related genes, Predicted membrane proteins" Autophagy "Deafness, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 46.0" "Cell type enhanced" "Detected in all" "Erythroid cells: 256.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015914 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 6: Erythroid cells - Oxygen transport" "Endoplasmic reticulum" "HPA015914: AB_1846794" "unprognostic (1.65e-1)" "unprognostic (1.45e-1)" "unprognostic (6.54e-3)" "unprognostic (8.02e-2)" "unprognostic (2.78e-2)" "unprognostic (3.56e-2)" "unprognostic (1.17e-3)" "unprognostic (3.48e-3)" "unprognostic (9.12e-3)" "unprognostic (2.04e-1)" "unprognostic (2.54e-1)" "unprognostic (2.86e-1)" "unprognostic (1.47e-1)" "unprognostic (4.66e-2)" "unprognostic (1.70e-1)" "unprognostic (1.87e-1)" "unprognostic (1.34e-1)" 11.2 19.1 2.4 5.5 2.7 6.0 9.0 3.9 3.2 9.5 4.1 11.5 1.7 9.5 5.3 12.5 8.8 4.3 10.5 2.6 3.2 17.9 46.0 10.7 5.5 2.9 2.9 8.9 20.0 5.4 12.8 3.1 3.0 9.5 3.8 6.1 12.0 1.9 7.4 9.7 10.9 3.0 2.7 14.7 11.4 6.5 3.0 4.0 13.6 1.7 3.5 9.8 10.1 4.0 16.8 5.5 5.8 7.2 14.2 15.2 3.7 12.6 4.6 5.4 8.2 6.5 27.7 12.1 10.9 12.2 12.9 8.1 28.2 10.1 24.8 10.7 4.2 10.5 3.6 6.7 10.1 18.7 16.1 5.9 15.1 23.0 17.8 5.2 9.8 6.7 22.7 21.3 14.7 4.6 16.5 5.4 11.2 5.7 4.0 6.7 5.9 22.2 13.6 5.3 13.4 7.8 7.5 12.8 12.8 6.6 8.5 4.0 4.4 15.8 17.8 21.3 7.8 16.3 23.5 24.2 11.2 5.7 12.6 4.6 2.8 5.8 2.6 2.7 2.7 2.5 2.6 2.7 2.7 2.1 1.7 2.2 2.0 4.4 3.1 3.5 3.5 2.3 2.4 2.7 3.9 3.2 2.6 3.2 2.9 2.9 3.0 2.7 3.0 4.0 24.2 25.6 26.1 10.1 65.3 85.7 45.3 131.0 60.3 33.5 61.2 51.3 27.8 58.6 70.4 77.3 20.9 74.2 52.7 52.9 72.4 101.8 12.2 39.9 41.8 35.8 43.0 256.8 17.5 77.2 131.0 39.6 39.8 48.3 57.8 24.2 26.0 159.9 110.9 30.3 22.1 94.2 146.5 93.5 128.9 6.9 23.9 66.4 69.4 12.2 78.4 36.9 45.3 17.6 25.9 74.3 88.5 33.8 194.3 63.7 82.7 203.9 63.1 33.1 32.9 22.1 41.6 41.7 36.7 56.4 90.1 56.8 54.0 33.4 68.6 53.9 CLCC1 MCLC ENSG00000121940 "Chloride channel CLIC like 1" Q96S66 1 108927361-108963504 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009087, HPA013210" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 47: Cytotrophoblasts - Unknown function" "Endoplasmic reticulum" "HPA009087: AB_1078532, HPA013210: AB_1846895" "unprognostic (2.95e-1)" "unprognostic (1.09e-1)" "prognostic favorable (1.33e-5)" "unprognostic (4.32e-2)" "unprognostic (2.55e-1)" "unprognostic (1.48e-1)" "unprognostic (2.40e-2)" "unprognostic (1.45e-1)" "unprognostic (5.30e-2)" "unprognostic (9.23e-2)" "unprognostic (1.14e-1)" "unprognostic (1.36e-1)" "unprognostic (7.50e-2)" "unprognostic (1.74e-1)" "unprognostic (2.04e-1)" "unprognostic (4.68e-3)" "unprognostic (9.65e-2)" 14.6 16.5 10.1 11.4 14.3 6.1 16.3 10.6 11.7 17.0 7.8 15.4 13.2 17.0 24.3 9.9 15.1 14.0 18.3 10.7 11.5 11.0 22.2 13.0 10.5 12.8 10.9 18.6 24.8 21.3 18.3 17.7 12.1 20.2 13.2 11.8 22.3 20.0 27.2 10.3 12.7 14.9 11.0 11.5 16.1 7.6 11.8 5.2 21.9 24.8 10.8 15.2 13.4 16.0 44.2 22.3 25.1 45.8 36.7 33.9 35.6 43.8 34.2 30.1 34.2 22.6 21.0 10.8 43.7 33.3 18.5 17.1 23.9 16.1 39.4 38.0 23.2 30.4 24.7 23.5 28.9 28.7 28.2 25.2 21.9 33.2 25.7 28.3 27.1 12.1 38.6 47.7 22.1 18.9 2.3 10.1 21.5 16.6 19.8 24.5 13.1 31.2 24.3 30.5 15.9 22.7 46.9 49.6 38.9 18.9 15.9 19.7 26.7 38.3 27.7 35.1 38.4 32.1 33.3 17.1 44.7 21.8 82.5 4.1 5.6 6.1 5.6 8.4 6.1 6.1 4.5 4.4 5.6 3.2 4.9 4.5 1.4 4.7 12.4 6.4 6.8 4.4 10.1 14.3 10.6 11.7 10.7 11.5 12.8 10.9 12.1 11.0 11.8 16.0 13.3 25.6 20.9 26.8 11.8 3.7 14.0 11.7 1.8 12.3 11.8 9.1 5.9 20.0 18.0 11.0 29.2 28.7 9.0 7.1 0.0 18.6 6.7 8.1 21.3 10.9 3.6 5.9 25.0 21.1 12.8 19.5 10.7 13.5 12.0 16.3 9.7 22.3 13.1 21.9 30.3 9.0 16.2 6.7 5.1 2.8 19.9 9.3 8.8 14.0 12.0 11.4 3.1 35.7 39.3 17.7 3.8 18.8 17.7 17.7 7.2 5.0 14.9 18.9 19.7 18.6 10.7 5.5 5.4 6.4 6.3 18.5 8.4 12.5 9.8 9.9 CLGN ENSG00000153132 Calmegin O14967 4 140388453-140427661 "Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 59.5;testis: 113.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 313.3;Early spermatids: 162.4;Endometrial ciliated cells: 93.4;Muller glia cells: 176.4;Spermatocytes: 465.5" "Cancer enhanced" "Detected in many" "prostate cancer: 19.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 53.0;MOLT-4: 47.8;U-251 MG: 73.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020709, HPA048761, HPA058627" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 43: Testis - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 66: Spermatocytes - Spermatogenesis" "Endoplasmic reticulum" "CAB020709: , HPA048761: AB_2680514, HPA058627: AB_2683782" "unprognostic (6.74e-2)" "unprognostic (8.28e-2)" "unprognostic (1.62e-1)" "unprognostic (1.08e-1)" "unprognostic (2.30e-2)" "unprognostic (2.56e-1)" "unprognostic (3.73e-3)" "unprognostic (6.14e-2)" "unprognostic (4.80e-2)" "unprognostic (3.11e-1)" "unprognostic (5.38e-3)" "unprognostic (2.29e-2)" "unprognostic (2.45e-3)" "unprognostic (3.00e-3)" "unprognostic (1.29e-1)" "unprognostic (2.59e-1)" "unprognostic (1.01e-1)" 0.4 6.6 0.9 1.0 0.7 2.4 2.7 3.8 1.6 0.9 2.0 2.6 0.5 1.6 0.6 1.2 13.7 0.4 59.5 0.9 2.6 0.4 3.2 0.5 0.7 2.7 1.9 0.3 2.2 0.6 11.2 0.2 2.6 22.5 1.3 17.2 1.0 0.7 0.4 0.2 1.3 1.5 1.2 0.2 2.0 113.6 2.3 2.4 2.7 1.6 1.2 0.6 0.1 0.9 0.2 10.2 10.3 6.9 4.0 21.1 2.4 0.1 9.4 10.0 18.6 0.3 0.9 0.0 27.8 0.9 8.4 0.2 7.5 0.1 16.2 0.4 9.0 3.0 9.8 7.4 41.4 38.9 0.6 2.2 39.2 1.0 0.9 53.0 0.2 9.6 2.0 0.0 0.0 0.5 47.8 0.5 12.0 0.2 28.1 31.5 0.0 0.4 0.0 0.3 16.8 29.8 6.5 4.1 1.8 3.8 1.9 5.6 0.0 27.4 4.7 9.7 73.6 14.4 31.7 19.9 43.4 1.6 2.9 0.9 0.2 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.7 3.8 1.6 0.9 2.6 2.7 1.9 2.6 1.2 2.3 0.9 0.8 0.0 2.2 0.3 0.1 0.0 0.9 8.5 1.2 9.2 3.3 1.8 313.3 0.0 6.4 0.0 4.2 0.5 0.0 0.5 0.0 1.2 162.4 93.4 1.3 11.9 5.3 8.6 7.2 4.2 0.1 10.2 0.0 11.3 0.0 10.1 0.7 3.7 0.1 25.2 6.7 0.4 30.5 0.0 0.0 60.2 5.0 0.7 1.8 0.0 0.1 176.4 0.0 6.6 0.6 0.9 3.9 4.5 0.1 33.8 0.2 0.1 24.6 16.3 0.0 0.6 2.0 465.5 23.9 2.8 0.1 0.3 0.7 0.2 0.8 1.3 CLPTM1 ENSG00000104853 "CLPTM1 regulator of GABA type A receptor forward trafficking" O96005 19 44954585-44993341 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068767 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "HPA068767: " "unprognostic (1.40e-1)" "unprognostic (1.32e-1)" "unprognostic (4.07e-1)" "unprognostic (2.19e-1)" "unprognostic (1.81e-1)" "unprognostic (3.25e-1)" "unprognostic (1.94e-1)" "unprognostic (5.93e-2)" "unprognostic (6.60e-3)" "unprognostic (2.67e-2)" "unprognostic (1.46e-3)" "unprognostic (2.62e-1)" "unprognostic (1.02e-2)" "unprognostic (3.30e-1)" "unprognostic (2.56e-1)" "unprognostic (7.46e-2)" "unprognostic (1.59e-1)" 69.1 152.8 54.7 34.3 56.9 27.3 62.7 40.1 103.3 56.7 36.4 63.6 50.6 58.5 36.0 70.2 51.6 27.4 106.5 54.4 50.1 92.9 130.7 54.6 33.4 56.3 58.4 63.5 86.6 78.0 60.2 38.8 50.9 63.4 32.9 35.1 66.6 43.1 109.0 87.4 66.0 37.0 34.8 64.8 81.0 76.2 60.0 25.4 63.2 51.3 43.4 55.0 57.6 55.5 88.5 213.8 48.6 96.9 158.3 63.4 52.5 90.8 102.0 107.5 114.9 93.3 95.0 96.1 93.1 124.2 79.0 112.0 87.2 84.4 72.3 72.4 126.8 74.5 74.7 79.3 111.6 59.9 83.2 99.8 87.8 102.9 66.1 76.3 75.9 54.7 78.7 129.3 96.2 86.9 58.1 35.0 43.9 139.3 73.6 60.4 52.8 93.1 100.1 132.7 57.4 59.5 115.6 169.1 51.4 43.0 92.7 47.1 72.4 119.9 73.7 60.4 116.0 82.4 180.2 65.5 98.9 58.3 112.7 17.7 28.4 43.5 25.8 38.4 21.4 27.1 27.9 37.3 24.9 27.4 21.7 18.7 24.6 21.4 49.5 38.8 26.3 22.9 54.7 56.9 40.1 103.3 54.4 50.1 56.3 58.4 50.9 34.8 60.0 55.5 33.9 6.4 7.8 25.5 31.9 36.7 36.1 68.4 25.0 40.3 36.6 26.8 12.3 41.5 42.1 36.8 39.6 94.0 27.7 82.7 13.7 77.3 53.0 23.5 27.5 32.7 40.7 21.5 20.7 74.1 83.7 35.7 30.1 36.0 10.8 31.7 31.4 46.6 75.2 43.7 22.9 47.1 65.1 29.3 29.9 51.1 30.1 31.2 33.8 9.4 87.8 57.2 23.7 24.6 19.1 68.4 64.7 30.1 58.3 40.3 106.0 62.7 17.7 36.3 26.3 30.3 32.5 33.5 29.6 31.5 44.0 120.0 26.0 67.3 49.4 35.6 CLPTM1L "CRR9, FLJ14400" ENSG00000049656 "CLPTM1 like" Q96KA5 5 1317752-1345099 "Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/84: 474.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014791 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 16: U-266 - Nucleosome" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "HPA014791: AB_1847250" "unprognostic (2.92e-2)" "unprognostic (1.34e-1)" "unprognostic (9.53e-2)" "unprognostic (8.43e-2)" "unprognostic (5.16e-3)" "unprognostic (1.17e-1)" "prognostic unfavorable (3.75e-4)" "unprognostic (3.42e-2)" "unprognostic (1.41e-1)" "unprognostic (5.47e-3)" "unprognostic (9.14e-3)" "unprognostic (1.06e-1)" "unprognostic (5.77e-3)" "unprognostic (8.57e-2)" "unprognostic (4.92e-2)" "unprognostic (4.54e-2)" "unprognostic (4.17e-2)" 37.7 37.2 23.1 28.9 23.5 28.9 35.6 23.1 26.6 28.5 34.0 41.5 45.4 32.1 15.2 36.0 29.2 18.0 33.4 24.3 24.9 58.4 133.9 49.7 37.4 24.8 31.5 24.8 74.1 22.3 36.2 20.1 23.7 33.4 20.1 5.3 65.0 21.5 23.8 36.6 43.4 17.2 24.8 59.3 67.7 43.1 26.4 41.4 48.7 10.0 29.6 35.7 27.9 24.5 71.1 117.6 39.5 106.8 63.0 26.9 103.9 71.0 46.9 62.9 61.8 129.3 109.8 67.2 212.7 67.2 138.3 60.8 53.7 59.4 28.6 275.4 147.8 35.7 261.5 86.2 70.5 93.6 87.0 43.4 66.6 57.6 53.9 46.1 51.6 149.7 81.7 222.9 48.0 116.5 104.2 121.7 72.9 77.2 126.2 86.6 64.1 207.5 49.0 66.8 41.4 82.0 123.5 106.0 56.6 32.8 177.7 138.7 38.5 74.2 211.0 51.9 103.4 399.4 474.2 109.0 55.4 139.9 86.7 5.1 4.9 10.1 5.6 4.8 6.6 7.6 5.9 5.6 4.6 10.3 5.6 6.6 3.9 10.1 8.1 9.3 7.7 4.0 23.1 23.5 23.1 26.6 24.3 24.9 24.8 31.5 23.7 24.8 26.4 24.5 33.4 57.7 64.7 7.2 50.2 22.3 23.3 24.3 8.0 10.1 40.4 36.4 12.7 51.5 30.4 29.5 14.6 11.2 35.1 49.0 5.9 17.9 2.8 32.1 27.5 25.4 44.5 17.0 13.7 32.3 26.6 23.2 27.5 35.0 24.7 40.4 26.0 113.8 23.7 21.9 10.7 52.2 14.2 39.5 16.0 6.2 17.4 27.9 16.0 7.5 22.4 28.7 27.8 12.1 12.7 45.6 29.0 19.2 95.6 48.3 46.1 66.2 31.0 11.5 13.1 19.4 21.3 28.9 40.3 14.4 23.4 10.9 24.4 60.3 39.8 33.3 COL10A1 ENSG00000123500 "Collagen type X alpha 1 chain" Q03692 6 116118909-116158747 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 15.5;choroid plexus: 39.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 26.6;Inhibitory neurons: 6.3;Microglial cells: 8.4;Oligodendrocytes: 27.9" "Cancer enhanced" "Detected in many" "breast cancer: 42.8;pancreatic cancer: 51.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "hTEC/SVTERT24-B: 39.7" "Low region specificity" "Detected in many" HPA053268 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 160000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA053268: " "unprognostic (3.83e-2)" "unprognostic (6.81e-2)" "unprognostic (7.20e-2)" "unprognostic (7.45e-3)" "unprognostic (2.33e-2)" "unprognostic (1.28e-1)" "unprognostic (3.84e-2)" "unprognostic (1.49e-1)" "unprognostic (1.91e-1)" "unprognostic (2.14e-1)" "unprognostic (4.37e-2)" "unprognostic (7.03e-2)" "unprognostic (1.38e-11)" "unprognostic (2.16e-3)" "unprognostic (7.22e-2)" "unprognostic (3.60e-1)" "unprognostic (2.06e-3)" 0.3 0.0 2.2 0.2 8.6 0.3 0.3 4.6 4.5 1.2 39.9 0.2 0.0 0.3 0.0 0.0 0.0 8.9 0.3 1.3 3.3 0.4 0.2 2.8 0.6 7.7 5.6 3.9 3.3 2.5 0.4 0.1 7.1 1.9 0.1 0.9 2.6 0.8 0.1 0.4 0.1 0.5 4.3 2.5 0.1 0.2 6.3 0.1 0.7 0.0 1.9 0.2 0.1 15.5 0.0 0.0 0.0 0.0 0.0 3.1 0.1 0.2 2.9 0.4 6.0 0.1 0.0 0.1 0.0 1.0 0.0 0.7 0.0 0.0 0.8 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.8 0.0 39.7 0.0 0.2 0.0 0.1 0.2 0.0 0.3 0.0 0.3 0.0 0.4 0.0 0.0 0.5 0.0 0.1 0.0 0.1 0.2 0.3 0.1 0.1 0.0 0.0 0.2 0.0 0.0 6.3 0.1 0.4 0.5 0.0 0.0 0.1 0.6 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.2 8.6 4.6 4.5 1.3 3.3 7.7 5.6 7.1 4.3 6.3 15.5 2.6 0.0 0.6 3.9 0.1 0.1 0.1 0.0 0.0 0.6 0.0 0.1 0.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.3 0.0 0.4 26.6 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.7 6.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 8.4 0.0 2.2 0.0 2.5 27.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.2 0.0 0.2 5.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 COL11A1 "CO11A1, COLL6, DFNA37, STL2" ENSG00000060718 "Collagen type XI alpha 1 chain" P12107 1 102876467-103108872 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Cataract, Deafness, Disease variant, Dwarfism, Ectodermal dysplasia, Non-syndromic deafness, Stickler syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 20.1;retina: 9.6" "Cell type enhanced" "Detected in some" "Astrocytes: 83.9;Excitatory neurons: 99.5;Oligodendrocyte precursor cells: 557.4;Theca cells: 139.6" "Cancer enhanced" "Detected in many" "breast cancer: 27.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 116.9;BJ: 43.2;BJ hTERT+ SV40 Large T+ RasG12V: 85.3;HBF TERT88: 48.7;HSkMC: 142.5;SuSa: 60.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA058335 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" No No 640000 "Cluster 28: Placenta - Pregnancy" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "Endoplasmic reticulum" "HPA058335: AB_2683682" "unprognostic (2.60e-3)" "unprognostic (6.61e-4)" "unprognostic (9.58e-2)" "unprognostic (5.06e-5)" "unprognostic (2.83e-1)" "unprognostic (2.85e-2)" "unprognostic (6.03e-3)" "unprognostic (2.23e-3)" "unprognostic (9.08e-2)" "unprognostic (1.21e-1)" "unprognostic (1.12e-2)" "unprognostic (1.94e-2)" "unprognostic (3.01e-12)" "unprognostic (1.27e-2)" "unprognostic (3.53e-1)" "unprognostic (3.54e-2)" "unprognostic (2.32e-2)" 0.6 0.6 4.3 0.3 3.1 0.0 0.4 1.6 4.6 0.9 2.8 0.4 0.1 0.5 0.1 0.0 0.0 3.1 0.0 2.4 2.5 0.1 0.0 0.3 0.1 2.5 3.7 0.6 0.7 0.2 3.3 20.1 2.2 0.2 0.3 9.6 1.5 0.8 0.1 1.4 0.1 0.3 1.0 0.5 0.1 1.4 2.2 0.0 0.1 0.1 0.0 0.2 0.1 2.1 0.0 0.8 116.9 0.0 4.6 5.9 0.0 43.2 16.1 23.3 85.3 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 48.7 0.0 0.0 0.0 0.0 0.0 12.2 0.0 0.0 142.5 0.0 1.1 0.0 17.7 0.0 0.0 0.0 0.0 31.6 0.0 0.0 0.0 8.1 0.0 0.1 0.0 7.4 0.0 15.2 0.0 0.1 0.0 0.0 0.1 0.0 60.5 0.0 0.1 0.0 0.6 27.0 0.0 4.7 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 3.1 1.6 4.6 2.4 2.5 2.5 3.7 2.2 1.0 2.2 2.1 0.0 0.0 2.2 83.9 0.0 1.8 0.0 0.0 0.0 9.4 0.1 4.2 0.5 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 21.0 0.1 0.9 2.2 0.0 0.0 99.5 0.0 0.8 18.7 0.0 0.0 2.5 8.3 0.0 0.0 0.3 0.0 32.9 0.0 0.0 0.0 1.3 4.0 1.2 0.2 10.6 29.0 0.0 29.8 0.0 557.4 6.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.9 2.6 0.5 0.8 0.0 1.1 0.3 0.2 139.6 0.0 0.0 COL15A1 ENSG00000204291 "Collagen type XV alpha 1 chain" P39059 9 98943179-99070792 "Plasma proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 229.2" "Cell type enhanced" "Detected in many" "Adipocytes: 307.0;Endothelial cells: 190.5;Fibroblasts: 202.3;Leydig cells: 326.8;Peritubular cells: 483.3;Theca cells: 333.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 26.4;BJ hTERT+: 55.6;HDLM-2: 24.5;K-562: 18.8;U-2197: 45.6;U-87 MG: 20.6;WM-115: 31.0" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 7 "spinal cord: 44.3" "HPA017913, HPA017915" Enhanced Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 28000000 "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "HPA017913: AB_1847099, HPA017915: AB_1847100" "unprognostic (4.30e-1)" "unprognostic (1.44e-1)" "unprognostic (1.41e-1)" "unprognostic (2.22e-2)" "unprognostic (2.09e-1)" "unprognostic (1.09e-2)" "prognostic favorable (5.47e-4)" "unprognostic (3.08e-2)" "unprognostic (1.05e-1)" "unprognostic (2.29e-1)" "unprognostic (1.84e-1)" "unprognostic (7.87e-2)" "unprognostic (1.20e-3)" "unprognostic (3.66e-3)" "unprognostic (8.98e-2)" "unprognostic (6.98e-2)" "prognostic unfavorable (3.08e-4)" 84.7 36.9 0.6 50.6 0.9 0.1 46.7 0.8 1.0 31.2 4.0 44.5 12.9 53.8 19.2 26.9 17.3 42.8 58.0 0.4 0.8 12.9 1.0 11.1 10.4 0.6 0.9 23.2 26.8 11.8 6.0 229.2 0.7 21.6 16.3 0.0 35.9 14.3 56.5 15.1 17.7 108.9 0.6 3.7 27.3 27.0 2.4 13.0 21.1 34.4 8.6 42.1 15.1 0.7 0.0 0.0 0.1 0.0 4.6 2.6 0.1 26.4 55.6 1.4 0.5 0.0 0.0 0.2 0.7 5.8 0.2 0.1 0.0 0.0 0.2 24.5 0.0 0.3 12.9 0.0 1.1 0.4 2.5 7.6 0.0 6.0 0.2 0.0 0.0 0.0 18.8 0.0 2.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 14.7 0.2 0.0 0.0 0.1 0.1 0.8 3.9 7.4 0.3 0.2 0.6 0.0 0.1 0.6 45.6 0.5 0.2 0.0 0.0 20.6 0.2 31.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.9 0.8 1.0 0.4 0.8 0.6 0.9 0.7 0.6 2.4 0.7 307.0 0.0 0.0 0.7 0.5 19.5 0.1 0.0 5.2 0.0 2.6 4.1 8.1 0.0 0.0 0.0 0.0 3.8 1.8 0.0 0.0 2.4 5.7 3.9 103.4 190.5 0.0 0.0 0.4 0.8 3.7 202.3 0.5 2.2 0.0 0.3 0.0 0.0 7.6 0.0 2.9 0.0 0.0 0.3 27.2 22.5 326.8 3.1 17.8 46.9 0.6 0.0 1.0 1.0 0.3 0.6 0.0 483.3 0.3 1.2 0.0 0.5 0.0 0.0 13.1 107.8 52.8 1.9 1.2 1.3 16.3 7.7 2.1 333.4 0.0 0.7 COL1A2 OI4 ENSG00000164692 "Collagen type I alpha 2 chain" P08123 7 94394895-94431227 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Dwarfism, Ehlers-Danlos syndrome, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 1831.7;gallbladder: 1378.0;smooth muscle: 1416.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 774.5;Fibroblasts: 2148.2;Glandular and luminal cells: 592.2;Leydig cells: 991.9;Peritubular cells: 501.0;Smooth muscle cells: 770.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 3899.2;ASC TERT1: 4637.0;BJ: 3995.6;BJ hTERT+: 2901.2;fHDF/TERT166: 13615.1;HSkMC: 4058.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 133.7" "CAB032650, HPA059738" Approved Supported "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 27000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB032650: AB_2082039, HPA059738: AB_2684116" "unprognostic (1.20e-1)" "unprognostic (6.34e-2)" "unprognostic (1.32e-1)" "unprognostic (3.40e-2)" "unprognostic (2.86e-2)" "unprognostic (2.81e-1)" "unprognostic (5.15e-2)" "unprognostic (7.38e-3)" "unprognostic (2.01e-2)" "unprognostic (1.40e-2)" "unprognostic (5.83e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.51e-9)" "unprognostic (1.35e-2)" "unprognostic (5.25e-2)" "unprognostic (1.15e-1)" "unprognostic (3.31e-3)" 514.8 52.4 6.8 266.2 9.3 2.0 314.5 7.1 17.4 1831.7 18.1 175.7 61.1 411.2 61.6 263.2 206.6 1378.0 275.4 6.0 6.8 40.8 27.4 229.5 91.6 8.7 6.7 297.2 57.1 32.5 33.5 624.6 7.9 196.2 141.8 1.6 60.2 232.3 51.6 424.6 103.2 1416.9 8.8 69.3 89.1 136.6 15.6 32.8 86.4 102.1 60.1 805.6 295.2 8.2 0.1 0.0 22.8 1488.5 3899.2 4637.0 1.3 3995.6 2901.2 642.6 850.5 0.0 2.8 0.3 2.7 13615.1 0.0 0.6 2.2 1.5 160.9 0.1 0.2 0.1 0.0 0.0 1018.6 1.1 0.5 4058.4 0.1 507.9 2.4 0.3 0.5 0.0 0.3 0.3 551.0 0.0 0.6 1.5 2.5 0.0 6.3 0.5 0.8 0.8 0.1 0.0 12.9 1.4 0.3 1.0 0.1 296.0 2.1 0.1 15.9 1626.3 0.8 1022.7 115.5 1.2 0.1 0.4 408.6 0.5 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 9.3 7.1 17.4 6.0 6.8 8.7 6.7 7.9 8.8 15.6 8.2 112.9 3.2 12.9 1.0 0.8 223.1 0.7 9.3 4.6 0.2 7.2 8.6 21.7 0.0 3.3 1.8 0.0 31.5 2.5 0.0 0.0 3.0 8.4 183.2 774.5 57.2 0.0 0.0 0.0 0.2 31.7 2148.2 26.5 592.2 10.1 16.4 258.8 1.9 116.9 0.0 0.1 0.0 0.0 1.0 394.5 45.1 991.9 16.7 238.3 97.4 2.6 3.2 0.0 0.0 0.2 5.2 0.0 501.0 4.5 1.0 0.0 0.5 0.8 0.4 302.4 249.9 770.7 9.9 4.5 6.2 187.4 70.7 30.6 214.8 0.0 0.8 COL20A1 KIAA1510 ENSG00000101203 "Collagen type XX alpha 1 chain" Q9P218 20 63293186-63334851 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 8.3;choroid plexus: 2.8;testis: 2.5" "Group enriched" "Detected in some" 11 "Oligodendrocyte precursor cells: 72.9;Spermatocytes: 21.8" "Cancer enriched" "Detected in single" 19 "glioma: 8.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA072382 Uncertain "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA "Cluster 65: Brain - Ion transport" "Cluster 68: Oligodendrocytes - Mixed function" "Endoplasmic reticulum" "HPA072382: " "unprognostic (6.34e-4)" "unprognostic (2.52e-1)" "unprognostic (1.29e-2)" "unprognostic (1.69e-1)" "unprognostic (2.01e-1)" "unprognostic (5.82e-2)" "unprognostic (1.29e-1)" "unprognostic (1.45e-1)" "unprognostic (1.21e-1)" "unprognostic (1.70e-2)" "unprognostic (1.71e-1)" "unprognostic (2.89e-1)" "unprognostic (8.41e-7)" "unprognostic (7.85e-2)" "unprognostic (1.04e-1)" "unprognostic (1.32e-2)" "unprognostic (1.16e-1)" 0.0 0.2 3.9 0.0 4.0 0.0 0.0 3.0 8.3 0.5 2.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 3.9 2.8 0.1 0.0 0.0 0.0 3.7 3.3 0.2 0.0 0.0 1.0 0.0 3.6 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 3.3 0.7 0.0 2.5 3.4 0.0 0.0 0.3 0.0 0.0 0.1 5.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 4.0 3.0 8.3 3.9 2.8 3.7 3.3 3.6 3.3 3.4 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 3.3 0.4 0.0 0.0 0.0 0.0 2.7 0.3 0.0 0.0 0.0 0.0 0.4 0.0 72.9 0.3 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 2.0 0.0 0.2 0.1 21.8 4.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 COL3A1 EDS4A ENSG00000168542 "Collagen type III alpha 1 chain" P02461 2 188974373-189012746 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Aortic aneurysm, Disease variant, Ehlers-Danlos syndrome, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 2369.0;gallbladder: 2092.8;placenta: 1981.7;smooth muscle: 2140.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 2812.0;Fibroblasts: 1764.2;Smooth muscle cells: 643.0;Theca cells: 466.8" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 4 "cerebral cortex: 15.0;thalamus: 10.9;white matter: 4.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 1362.4;ASC diff: 2465.0;ASC TERT1: 4252.6;fHDF/TERT166: 1815.7;HHSteC: 1690.0;HSkMC: 3189.5" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 61.1" "HPA007583, CAB016766, CAB059993" Approved Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 32000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB016766: , CAB059993: AB_2314211, HPA007583: AB_1078548" "unprognostic (1.12e-1)" "unprognostic (2.03e-2)" "unprognostic (1.02e-1)" "unprognostic (6.01e-2)" "unprognostic (2.78e-1)" "unprognostic (2.04e-1)" "unprognostic (6.94e-2)" "unprognostic (6.77e-3)" "unprognostic (3.57e-3)" "unprognostic (2.60e-2)" "unprognostic (1.89e-2)" "unprognostic (1.99e-1)" "prognostic unfavorable (3.59e-10)" "unprognostic (1.70e-3)" "unprognostic (3.76e-2)" "unprognostic (7.61e-2)" "unprognostic (6.17e-3)" 763.6 48.9 1.1 575.5 2.3 1.1 340.0 1.4 15.0 2369.0 11.5 275.9 84.5 768.9 60.9 298.5 177.6 2092.8 234.6 1.3 1.4 42.9 97.4 187.0 119.0 1.8 2.0 146.9 45.2 37.0 13.6 1981.7 2.2 147.5 334.7 0.0 65.6 276.9 67.1 329.8 152.5 2140.7 1.9 134.7 156.9 63.5 10.9 40.9 71.8 71.8 73.1 1097.6 273.8 4.6 0.0 0.2 1362.4 53.0 2465.0 4252.6 0.9 558.6 495.3 239.4 212.8 8.1 0.0 0.6 0.3 1815.7 0.1 0.8 1.1 1.0 26.4 0.0 0.9 0.7 228.9 0.2 1690.0 2.0 0.6 3189.5 0.0 291.5 46.9 1.0 12.5 0.0 0.4 0.0 146.4 0.0 0.2 1.4 2.6 0.1 1.7 0.3 38.5 0.5 0.0 7.2 1.3 21.1 14.5 0.4 0.0 954.8 0.1 0.0 0.7 2.3 28.0 117.3 0.5 2.8 1.3 0.4 0.5 1.1 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 2.3 1.4 15.0 1.3 1.4 1.8 2.0 2.2 1.9 10.9 4.6 111.8 3.2 13.7 0.0 0.6 171.6 0.4 1.9 3.4 0.0 7.7 9.9 11.1 0.0 1.3 0.0 0.0 57.9 1.6 0.0 0.0 2.4 29.0 75.4 2812.0 68.4 6.0 0.0 0.0 0.0 58.1 1764.2 4.1 60.7 6.3 9.7 235.2 0.9 91.1 0.0 0.2 0.0 0.0 0.6 275.3 20.8 323.1 17.5 172.5 20.6 0.0 0.0 0.0 0.0 0.0 3.7 0.0 235.9 1.5 0.6 0.0 0.2 1.6 0.0 453.6 224.3 643.0 0.9 1.5 2.2 155.7 126.3 29.1 466.8 0.0 0.4 COL4A6 ENSG00000197565 "Collagen type IV alpha 6 chain" Q14031 X 108155607-108439497 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cell adhesion" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 32.6;urinary bladder: 40.7" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 24.5;Basal respiratory cells: 16.0;Cardiomyocytes: 13.1;Prostatic glandular cells: 12.1;Urothelial cells: 15.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 46.0;HeLa: 40.1;HHSteC: 59.2;hTERT-HME1: 44.1;HUVEC TERT2: 41.7;TIME: 94.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA065393 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Endoplasmic reticulum" "HPA065393: AB_2685483" "unprognostic (8.47e-3)" "unprognostic (4.50e-3)" "unprognostic (9.75e-3)" "unprognostic (9.80e-3)" "unprognostic (1.18e-1)" "unprognostic (5.99e-2)" "unprognostic (1.78e-2)" "unprognostic (3.78e-2)" "unprognostic (1.72e-1)" "unprognostic (9.84e-2)" "unprognostic (1.40e-2)" "unprognostic (4.11e-2)" "unprognostic (1.26e-1)" "unprognostic (1.32e-2)" "unprognostic (2.06e-1)" "unprognostic (8.54e-3)" "unprognostic (3.51e-1)" 3.0 0.5 0.3 0.4 0.3 0.0 2.0 0.2 0.2 12.6 1.3 1.9 1.4 32.6 17.0 5.5 14.9 13.3 5.4 0.3 0.7 4.2 0.1 1.0 0.1 0.9 1.7 9.3 0.1 5.5 7.2 3.2 1.0 12.5 2.1 1.2 1.4 21.5 1.4 6.5 1.5 24.5 0.4 1.4 13.3 1.2 0.3 0.9 0.7 1.2 0.1 40.7 9.2 0.6 0.1 31.1 9.9 0.0 24.2 1.7 0.0 0.0 1.8 0.3 0.2 17.9 0.0 0.0 0.0 0.0 3.9 5.8 10.3 46.0 0.8 0.4 8.8 0.8 40.1 0.3 59.2 0.0 0.0 2.6 27.8 6.5 44.1 0.1 41.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 14.0 0.0 3.8 0.0 0.0 0.0 1.9 3.4 0.0 0.0 2.4 0.0 0.0 18.2 0.9 0.0 94.2 0.0 0.1 5.5 0.1 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.2 0.3 0.7 0.9 1.7 1.0 0.4 0.3 0.6 0.1 0.0 0.0 6.2 0.0 6.4 24.5 16.0 3.4 0.2 2.3 6.1 13.1 0.0 2.6 1.8 0.0 0.1 0.0 0.0 1.9 0.0 2.1 0.7 6.0 0.4 0.0 0.0 0.4 0.0 0.0 6.2 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.4 0.0 2.0 0.0 0.3 0.3 4.1 0.0 0.0 8.4 0.0 5.5 0.0 0.0 0.6 0.1 0.0 9.1 0.0 12.1 0.0 0.0 2.2 0.4 0.0 0.4 7.2 0.2 0.2 0.1 3.7 0.0 0.1 0.8 0.0 15.2 CPVL ENSG00000106066 "Carboxypeptidase vitellogenic like" Q9H3G5 7 28995235-29195451 "Enzymes, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 219.0" "Cell type enhanced" "Detected in many" "Hofbauer cells: 306.1;Kupffer cells: 290.3;Langerhans cells: 531.0;Macrophages: 266.2;monocytes: 176.8" "Cancer enhanced" "Detected in all" "thyroid cancer: 61.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 1136.9;intermediate monocyte: 953.5;myeloid DC: 1319.5" "Group enriched" "Detected in all" 52 "dendritic cells: 1319.5;monocytes: 1136.9" "Cell line enhanced" "Detected in many" "BEWO: 190.8;RPTEC TERT1: 801.1;U-266/84: 205.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB003697, HPA045715, HPA056466" Enhanced Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA 760000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 41: Macrophages - Immune response" "Endoplasmic reticulum" "CAB003697: AB_425990, HPA045715: AB_2679429, HPA056466: AB_2683140" "unprognostic (4.72e-2)" "unprognostic (7.08e-2)" "unprognostic (5.96e-2)" "prognostic unfavorable (8.56e-6)" "unprognostic (1.63e-1)" "unprognostic (2.49e-2)" "unprognostic (6.85e-3)" "unprognostic (7.01e-2)" "unprognostic (1.49e-1)" "unprognostic (4.98e-2)" "unprognostic (3.07e-1)" "unprognostic (4.25e-2)" "unprognostic (1.56e-2)" "unprognostic (1.79e-3)" "unprognostic (2.21e-1)" "unprognostic (7.46e-3)" "prognostic unfavorable (4.99e-4)" 44.0 23.5 7.5 66.3 8.7 59.8 24.9 48.9 12.0 28.5 39.6 28.9 32.8 17.1 34.6 25.4 19.8 42.1 79.3 6.8 9.9 96.7 52.9 57.6 92.9 15.2 11.4 18.1 7.9 5.4 10.1 84.9 15.4 17.9 25.7 0.9 5.3 21.3 12.5 19.3 46.5 34.1 11.8 219.0 15.5 34.4 8.8 66.7 128.4 8.3 35.8 50.6 15.8 23.4 1.5 0.2 20.3 0.1 0.1 0.0 190.8 0.0 0.0 1.9 0.4 59.8 0.1 0.0 90.3 0.8 94.4 3.2 51.8 4.2 0.6 0.4 47.9 67.0 1.2 144.5 0.0 0.0 0.3 0.3 5.9 0.7 1.6 0.0 0.6 27.5 45.5 0.1 1.6 0.0 63.4 0.4 31.6 0.1 16.0 0.3 0.0 0.6 801.1 22.8 11.9 9.4 53.6 125.5 101.7 97.0 15.1 49.6 0.0 0.4 0.8 0.5 12.0 17.5 205.5 1.0 0.2 25.0 20.8 19.5 1136.9 5.7 2.6 953.5 3.4 1.8 1.3 1.9 1319.5 1.2 1.2 1.2 23.4 5.8 327.8 34.8 1.5 1142.7 7.5 8.7 48.9 12.0 6.8 9.9 15.2 11.4 15.4 11.8 8.8 23.4 12.3 6.4 16.0 3.3 7.2 12.5 1.3 0.7 5.7 0.0 2.6 3.4 69.1 10.0 2.5 71.7 0.0 138.0 2.1 0.2 35.2 0.5 24.7 3.7 0.3 21.1 1.8 34.1 3.7 15.6 118.3 29.4 1.1 0.6 5.1 2.3 6.8 1.1 306.1 0.0 1.7 1.2 0.0 290.3 531.0 7.6 9.3 266.2 10.6 45.9 176.8 0.2 2.1 2.0 1.3 0.8 0.4 3.0 2.9 0.5 0.4 30.6 1.5 0.4 0.0 31.0 3.0 27.1 92.8 27.2 8.8 118.5 3.3 3.6 1.2 0.9 CSGALNACT2 "GALNACT-2, GALNACT2, MGC40204, PRO0082" ENSG00000169826 "Chondroitin sulfate N-acetylgalactosaminyltransferase 2" Q8N6G5 10 43138445-43185302 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "bone marrow: 133.9" "Cell type enhanced" "Detected in many" "Langerhans cells: 121.6;Macrophages: 82.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031540 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" "Endoplasmic reticulum" "HPA031540: AB_10599943" "unprognostic (1.65e-1)" "unprognostic (2.70e-2)" "unprognostic (9.10e-2)" "unprognostic (6.41e-2)" "unprognostic (1.95e-1)" "unprognostic (8.28e-3)" "unprognostic (2.85e-3)" "unprognostic (4.95e-2)" "unprognostic (2.96e-1)" "unprognostic (3.43e-3)" "unprognostic (7.65e-2)" "unprognostic (1.90e-1)" "prognostic unfavorable (3.53e-7)" "unprognostic (2.68e-2)" "unprognostic (1.40e-1)" "unprognostic (2.47e-1)" "unprognostic (4.05e-3)" 19.7 10.6 8.8 24.1 10.8 133.9 12.9 15.1 13.3 15.1 12.6 15.1 9.2 19.5 8.4 10.5 15.5 25.4 12.8 8.5 10.8 8.8 13.9 26.8 22.5 10.7 9.7 17.0 7.8 8.0 11.6 26.4 11.1 13.4 11.6 9.8 7.9 10.9 14.6 11.0 11.5 20.8 9.4 26.5 10.1 9.2 9.9 27.9 9.9 17.2 17.4 24.0 12.1 13.5 12.6 8.2 15.1 14.4 23.0 38.5 3.7 44.7 59.8 19.3 30.0 2.9 12.7 20.8 10.8 40.6 9.2 11.4 12.6 16.8 31.3 24.9 9.3 10.8 7.9 8.6 50.0 25.3 21.8 38.6 18.1 43.1 89.3 24.3 25.0 30.7 4.6 60.1 39.9 6.5 19.3 15.1 6.5 4.2 10.7 11.9 15.0 8.8 17.1 6.6 13.6 26.8 11.6 11.9 28.8 13.0 15.7 20.5 37.3 16.5 26.2 52.3 30.4 15.4 23.2 10.9 35.1 60.8 7.9 14.7 11.9 19.4 7.3 14.2 6.4 3.0 5.5 5.7 14.4 3.0 6.4 5.4 11.2 11.3 21.8 4.1 7.1 6.9 8.8 10.8 15.1 13.3 8.5 10.8 10.7 9.7 11.1 9.4 9.9 13.5 16.3 16.0 18.7 23.8 20.5 17.7 13.3 7.0 6.2 13.1 10.7 8.5 10.9 5.7 9.6 11.0 10.4 2.1 47.8 1.7 0.0 5.9 2.1 12.0 22.0 16.8 9.0 18.5 42.5 6.9 6.1 31.4 4.6 11.3 48.1 23.5 11.4 11.9 16.4 8.4 41.1 1.6 4.1 68.6 121.6 1.4 17.1 82.6 8.8 16.9 41.5 4.1 35.0 45.2 54.5 13.7 3.1 12.4 33.8 12.7 1.5 4.4 5.8 8.5 26.3 27.7 25.3 17.8 18.3 3.6 12.1 1.5 37.4 7.2 1.6 7.0 CYB5R3 DIA1 ENSG00000100243 "Cytochrome b5 reductase 3" P00387 22 42617840-42649392 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 830.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001566 Approved Supported "Endoplasmic reticulum" NA NA 1500000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Endoplasmic reticulum" "HPA001566: AB_1078601" "unprognostic (4.73e-2)" "unprognostic (2.93e-1)" "unprognostic (1.79e-1)" "unprognostic (1.89e-1)" "unprognostic (3.05e-1)" "unprognostic (1.04e-2)" "prognostic unfavorable (2.13e-5)" "unprognostic (2.45e-1)" "unprognostic (8.22e-3)" "unprognostic (3.01e-1)" "unprognostic (2.72e-2)" "unprognostic (6.76e-2)" "unprognostic (3.33e-3)" "unprognostic (1.31e-1)" "unprognostic (1.64e-1)" "unprognostic (1.92e-1)" "unprognostic (5.24e-2)" 404.4 310.5 147.1 87.4 152.9 82.7 272.2 145.7 189.9 237.3 115.0 192.4 94.8 248.4 58.8 152.4 174.0 139.5 374.3 138.7 163.9 182.9 279.4 201.3 76.3 194.7 174.2 218.3 89.1 62.0 137.4 107.8 169.9 181.4 74.9 27.3 149.8 239.3 203.0 233.6 138.1 200.2 154.8 101.4 182.0 142.7 156.7 54.0 157.8 140.5 72.3 216.7 210.0 160.2 125.5 78.6 126.6 78.6 830.9 654.7 74.4 359.2 330.0 262.2 232.4 104.0 95.6 58.8 156.6 668.8 113.8 112.4 85.3 178.0 133.7 63.9 187.3 83.6 127.3 202.4 211.0 118.4 149.5 397.4 138.1 188.9 124.5 190.8 220.0 74.0 73.5 296.3 361.9 137.9 116.8 108.4 51.0 129.2 142.7 84.9 153.8 131.3 202.0 90.6 56.1 73.2 118.6 113.2 134.0 92.6 90.6 112.0 340.9 282.0 175.3 192.3 137.9 78.3 91.2 72.4 328.8 67.8 237.9 126.3 104.0 300.3 75.9 135.3 76.6 110.1 72.8 83.9 154.0 102.7 50.8 54.0 53.8 63.5 176.7 140.8 95.0 86.4 147.1 152.9 145.7 189.9 138.7 163.9 194.7 174.2 169.9 154.8 156.7 160.2 238.5 86.6 62.2 17.0 51.7 110.1 95.5 184.8 27.3 16.7 52.3 73.2 106.4 105.8 100.9 60.7 4.2 110.0 37.0 90.5 49.0 216.4 4.8 51.4 82.9 161.5 83.7 113.9 12.3 107.0 199.3 183.4 38.2 65.4 62.8 57.8 180.2 230.4 108.3 16.8 16.1 45.8 142.4 50.6 112.0 17.0 253.9 67.7 176.1 25.3 112.5 91.0 33.0 7.1 26.4 156.8 85.6 280.6 36.7 82.3 116.9 110.8 53.3 18.4 190.7 62.5 202.5 23.8 45.5 57.5 112.7 117.9 43.0 233.1 55.2 96.4 CYP2S1 ENSG00000167600 "Cytochrome P450 family 2 subfamily S member 1" Q96SQ9 19 41193210-41207539 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "intestine: 101.3;stomach 1: 120.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 31.0;Gastric mucus-secreting cells: 110.6;Intestinal goblet cells: 29.2;Langerhans cells: 73.0;Proximal enterocytes: 50.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "classical monocyte: 24.7;myeloid DC: 84.4" "Group enriched" "Detected in many" 131 "dendritic cells: 84.4;monocytes: 24.7" "Cell line enhanced" "Detected in many" "A549: 99.4;CACO-2: 49.8;HaCaT: 50.3;NTERA-2: 69.6;OE19: 158.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049227, HPA069248" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 41: Macrophages - Immune response" "Endoplasmic reticulum" "HPA049227: AB_2680681, HPA069248: AB_2732128" "unprognostic (1.49e-2)" "unprognostic (7.45e-2)" "unprognostic (2.45e-2)" "unprognostic (6.03e-2)" "unprognostic (3.93e-2)" "unprognostic (7.46e-2)" "unprognostic (1.27e-2)" "unprognostic (4.85e-2)" "unprognostic (2.18e-1)" "unprognostic (1.54e-2)" "unprognostic (6.25e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.60e-6)" "unprognostic (1.06e-1)" "unprognostic (1.10e-1)" "unprognostic (1.02e-1)" "unprognostic (7.66e-2)" 1.8 1.1 1.4 6.7 1.4 1.8 0.9 3.1 1.5 2.7 1.2 26.7 101.3 0.5 0.2 14.5 6.3 5.5 0.5 1.3 4.1 1.1 1.4 7.1 1.7 6.3 10.0 0.3 0.6 0.7 1.2 1.6 6.1 1.3 18.6 0.2 5.0 0.9 0.2 3.7 65.3 1.7 2.2 6.1 120.4 0.8 3.6 3.2 0.6 0.2 13.2 3.6 4.0 2.5 3.8 99.4 0.0 0.1 0.0 0.0 4.5 0.6 0.8 1.0 0.2 49.8 13.6 0.2 10.4 0.7 0.1 50.3 16.6 25.0 0.4 0.0 0.3 12.9 5.1 19.1 19.4 0.0 0.4 0.8 1.4 1.4 0.8 0.2 0.8 4.3 5.8 0.2 0.0 2.0 0.3 0.2 69.6 158.6 12.5 0.2 0.0 0.9 1.5 20.4 0.1 0.6 9.1 0.0 0.0 27.8 12.2 4.7 10.6 0.1 4.0 1.7 0.0 0.5 0.0 0.0 0.5 2.1 0.1 0.0 24.7 0.0 0.0 5.9 0.4 0.0 0.0 0.1 84.4 0.0 0.0 0.0 0.2 0.1 3.7 3.2 0.0 11.4 1.4 1.4 3.1 1.5 1.3 4.1 6.3 10.0 6.1 2.2 3.6 2.5 0.3 0.0 6.9 1.0 0.7 2.5 2.0 18.2 23.3 0.0 0.1 0.3 1.2 0.0 7.6 1.8 0.0 24.9 0.1 31.0 0.0 0.7 0.3 7.4 0.3 0.4 0.0 0.0 0.4 1.0 1.1 0.8 110.6 0.3 1.3 0.1 0.4 0.0 14.5 0.0 0.5 29.2 0.0 5.7 73.0 0.0 0.0 16.0 0.0 1.0 7.2 0.0 0.0 0.5 0.1 23.7 22.3 0.0 0.4 0.5 50.7 0.2 10.8 0.0 0.0 0.3 0.9 0.1 0.4 4.0 2.8 10.3 0.3 0.0 14.1 0.5 CYP51A1 "CP51, CYP51, CYPL1, LDM, P450-14DM, P450L1" ENSG00000001630 "Cytochrome P450 family 51 subfamily A member 1" Q16850 7 92112153-92134803 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Monooxygenase, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 204.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 67.3;Alveolar cells type 2: 169.7;Early spermatids: 74.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "GAMG: 481.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041325, HPA043508" Enhanced Enhanced "Endoplasmic reticulum" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 37: Intestine - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 11: Alveolar cells - Smell perception" "Endoplasmic reticulum" "HPA041325: AB_2677411, HPA043508: AB_2678520" "unprognostic (6.68e-2)" "prognostic unfavorable (6.12e-4)" "unprognostic (3.48e-2)" "unprognostic (1.18e-2)" "unprognostic (7.82e-2)" "unprognostic (3.60e-2)" "unprognostic (1.02e-1)" "unprognostic (1.97e-1)" "unprognostic (9.84e-2)" "unprognostic (1.36e-1)" "unprognostic (9.75e-2)" "unprognostic (1.34e-1)" "unprognostic (1.59e-9)" "unprognostic (1.82e-1)" "unprognostic (2.73e-1)" "unprognostic (5.13e-2)" "unprognostic (1.09e-3)" 19.4 58.2 22.3 20.6 24.9 30.3 30.6 39.8 32.3 26.4 21.0 52.7 86.6 21.2 35.8 43.7 16.7 24.3 20.7 24.2 39.0 38.7 204.7 53.2 13.1 60.1 42.3 29.0 48.7 59.6 17.1 21.9 50.6 43.8 41.5 31.4 20.3 17.5 7.9 26.5 40.0 20.4 46.6 13.4 45.1 86.4 31.8 6.6 33.6 11.7 16.6 21.3 26.2 57.0 113.7 54.3 134.0 86.4 92.0 149.6 18.7 37.7 112.7 47.1 128.8 131.8 201.7 98.1 57.9 65.3 481.6 96.2 118.1 237.0 55.3 40.3 82.6 27.9 51.1 99.7 125.7 56.0 39.4 109.1 105.7 185.6 194.0 42.2 49.4 19.8 108.2 217.8 56.4 115.6 12.5 53.8 100.7 45.9 53.4 40.3 27.8 222.8 216.7 187.9 94.1 62.5 80.0 156.3 117.2 60.6 56.9 69.5 59.5 65.0 70.6 95.2 49.8 72.8 70.5 88.1 49.8 75.5 85.2 2.8 11.1 3.9 11.6 16.3 7.7 15.6 8.0 8.9 16.3 12.3 7.1 9.6 1.5 7.8 10.3 14.3 6.7 8.2 22.3 24.9 39.8 32.3 24.2 39.0 60.1 42.3 50.6 46.6 31.8 57.0 3.1 67.3 169.7 35.9 24.0 2.5 1.6 4.6 48.9 2.6 6.7 3.7 1.6 7.2 44.5 1.8 2.1 1.5 8.9 20.3 1.9 10.7 74.4 10.7 8.1 7.7 10.8 11.6 34.3 19.8 1.0 9.1 43.3 16.4 28.5 4.1 5.3 45.2 1.5 0.0 39.6 13.1 2.0 5.6 1.9 34.4 3.7 9.2 0.0 15.9 1.3 2.4 0.0 39.2 53.1 14.2 11.7 1.5 34.3 1.4 9.6 1.5 15.7 1.9 0.0 4.0 6.5 7.8 4.2 51.4 5.4 4.4 12.2 9.3 11.9 2.5 DDOST "GATD6, KIAA0115, OST, OST48, WBP1" ENSG00000244038 "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit" P39656 1 20651767-20661544 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 350.7;Syncytiotrophoblasts: 349.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009746, HPA046841, HPA052867" Supported Supported "Endoplasmic reticulum" NA NA 120000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "CAB009746: AB_2092075, HPA046841: AB_2679834, HPA052867: AB_2681977" "unprognostic (8.57e-3)" "unprognostic (1.35e-2)" "unprognostic (1.57e-2)" "prognostic favorable (5.99e-4)" "unprognostic (1.62e-1)" "prognostic unfavorable (4.88e-4)" "prognostic unfavorable (2.64e-5)" "unprognostic (1.33e-1)" "unprognostic (5.51e-3)" "unprognostic (2.70e-2)" "unprognostic (3.59e-2)" "unprognostic (3.72e-1)" "prognostic unfavorable (9.05e-7)" "unprognostic (1.07e-1)" "unprognostic (2.98e-1)" "unprognostic (1.69e-2)" "unprognostic (1.07e-1)" 98.1 132.7 44.6 108.5 46.4 191.4 111.9 44.9 46.3 130.7 64.1 161.4 119.4 115.8 224.5 113.2 137.4 98.2 123.4 47.2 53.7 100.6 137.2 104.4 104.6 48.1 45.3 139.5 259.8 112.7 119.1 183.3 46.9 99.8 165.7 42.1 151.7 130.4 80.0 87.3 108.4 122.8 46.1 113.1 139.0 83.4 52.4 84.0 185.6 66.4 121.6 119.3 92.8 51.4 366.0 206.7 178.8 533.9 347.4 359.8 376.6 286.1 545.9 435.5 445.3 278.9 678.8 275.8 501.8 447.0 238.7 292.7 250.4 334.3 321.3 257.0 256.3 235.7 138.5 375.0 513.2 377.5 618.8 371.6 370.2 365.2 439.5 522.8 504.1 180.5 116.3 445.0 266.5 251.1 179.6 308.2 196.5 529.8 214.2 164.5 238.6 492.2 358.7 150.4 133.0 238.3 294.0 299.1 413.5 257.1 237.8 566.8 260.2 249.7 279.6 435.1 274.6 586.1 677.5 195.6 409.4 489.4 342.0 272.0 268.3 257.3 255.6 284.2 270.3 230.4 218.1 239.9 389.7 207.8 203.1 209.6 63.8 266.1 251.4 320.1 256.0 490.6 44.6 46.4 44.9 46.3 47.2 53.7 48.1 45.3 46.9 46.1 52.4 51.4 62.0 35.3 72.3 7.5 93.6 50.2 95.8 200.6 47.3 18.3 70.0 62.5 22.1 77.2 120.0 35.0 29.2 350.7 92.9 52.5 39.2 162.5 29.9 44.7 71.9 65.2 71.8 49.6 10.9 148.3 270.0 102.8 74.5 71.6 79.1 113.2 55.3 74.4 140.8 16.8 9.4 152.6 79.3 66.8 78.8 13.9 74.6 74.5 85.4 6.5 96.4 54.1 87.6 15.6 10.7 93.5 89.7 60.9 320.5 68.9 69.1 54.3 78.9 24.6 46.0 42.5 103.3 136.0 171.3 55.1 53.6 349.7 78.5 122.9 133.7 84.3 DERL1 "DER-1, DER1, derlin-1, FLJ13784, MGC3067, PRO2577" ENSG00000136986 "Derlin 1" Q9BUN8 8 123013170-123042302 "Plasma proteins, Predicted membrane proteins, Transporters" "Host-virus interaction, Protein transport, Transport, Unfolded protein response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 225.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 825.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016562, CAB037269" Supported Supported "Endoplasmic reticulum" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "CAB037269: AB_609868, HPA016562: AB_1847611" "prognostic unfavorable (2.43e-4)" "unprognostic (4.30e-2)" "unprognostic (2.21e-1)" "prognostic unfavorable (5.66e-5)" "unprognostic (9.48e-2)" "unprognostic (4.21e-3)" "unprognostic (2.76e-1)" "unprognostic (1.28e-3)" "unprognostic (4.42e-2)" "unprognostic (5.38e-2)" "unprognostic (1.41e-3)" "unprognostic (4.35e-1)" "prognostic unfavorable (1.58e-4)" "unprognostic (1.88e-3)" "unprognostic (2.51e-1)" "unprognostic (1.85e-1)" "unprognostic (1.31e-1)" 69.1 47.6 15.2 53.7 16.4 104.1 34.1 20.2 18.2 26.6 26.6 50.0 47.9 29.4 31.4 35.4 29.4 32.9 41.3 17.9 18.3 30.8 77.5 37.1 48.7 15.7 16.4 38.1 31.6 26.9 23.0 28.0 15.7 27.0 42.8 29.6 29.6 28.7 73.3 23.6 47.0 34.4 16.7 40.0 38.5 32.1 18.0 27.2 42.4 49.1 55.5 41.8 22.5 19.5 130.8 93.9 55.7 72.6 98.3 72.8 47.1 108.9 72.1 68.7 85.1 59.7 126.9 150.7 129.8 87.4 81.2 107.0 51.8 69.3 97.4 174.9 57.6 157.2 62.9 51.6 89.2 62.2 111.0 66.9 87.8 76.0 89.8 62.5 62.8 60.6 95.9 193.7 78.7 254.8 68.5 39.4 42.1 166.4 82.5 68.3 46.2 252.1 182.2 92.1 60.5 89.8 109.9 825.1 68.6 59.6 97.3 55.4 74.2 82.2 154.1 74.1 102.1 239.5 444.6 136.5 135.4 76.4 79.4 73.1 60.7 72.6 89.3 75.7 93.0 69.8 59.5 74.0 49.5 56.1 41.0 64.0 42.1 77.8 77.9 56.6 80.0 83.3 15.2 16.4 20.2 18.2 17.9 18.3 15.7 16.4 15.7 16.7 18.0 19.5 38.6 32.1 25.9 12.4 78.3 42.3 41.8 57.3 26.7 22.6 38.3 21.3 28.1 17.2 44.8 29.5 20.9 41.0 67.6 43.3 9.8 87.7 85.5 18.9 32.3 39.2 30.5 41.0 11.5 75.4 71.4 43.8 26.5 31.2 42.6 24.0 39.3 75.9 68.0 18.5 12.8 62.2 42.7 49.4 44.2 19.9 24.5 45.6 60.5 14.0 47.6 25.5 59.8 17.6 19.1 68.4 40.6 25.6 225.0 63.7 56.6 28.0 31.3 25.6 46.0 32.7 77.6 75.4 40.3 41.0 50.7 78.0 69.8 34.8 37.5 64.4 DERL2 "CGI-101, derlin-2, F-LAN-1, F-LANa, FLANa" ENSG00000072849 "Derlin 2" Q9GZP9 17 5471254-5486811 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction, Unfolded protein response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 259.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037287, HPA048957, HPA056551" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Endoplasmic reticulum" "CAB037287: AB_1078641, HPA048957: AB_2680570, HPA056551: AB_2683171" "unprognostic (2.54e-1)" "unprognostic (5.30e-2)" "unprognostic (5.83e-2)" "prognostic favorable (7.26e-4)" "unprognostic (1.51e-2)" "unprognostic (4.70e-2)" "unprognostic (1.36e-1)" "unprognostic (2.63e-1)" "unprognostic (2.17e-1)" "unprognostic (1.12e-3)" "unprognostic (1.73e-3)" "unprognostic (5.23e-2)" "prognostic unfavorable (6.49e-4)" "unprognostic (1.91e-1)" "unprognostic (1.82e-1)" "unprognostic (3.73e-1)" "unprognostic (2.91e-2)" 14.5 18.8 5.7 16.4 6.0 33.9 12.9 6.3 7.6 13.1 7.0 12.9 14.9 12.8 29.6 15.3 14.0 17.3 10.2 5.4 6.2 14.0 28.0 11.3 18.2 6.4 6.4 12.8 28.5 14.7 12.1 13.4 6.6 14.0 12.3 8.1 28.3 11.4 10.6 10.1 17.5 12.4 6.2 15.1 15.5 24.4 6.1 10.8 24.6 4.9 15.4 14.9 11.1 7.6 32.0 40.4 18.8 31.7 31.5 23.6 24.0 44.5 36.1 30.0 36.4 27.8 27.9 22.0 39.2 28.5 33.6 35.0 13.2 25.7 29.9 29.3 27.6 10.8 25.8 30.0 43.4 8.1 25.2 22.0 21.0 40.6 34.9 26.4 31.4 22.4 12.0 37.5 40.9 16.5 17.3 12.3 18.2 20.7 16.0 20.8 26.6 16.3 32.5 16.2 7.9 23.2 27.1 18.5 47.6 20.6 24.8 11.8 23.9 35.4 23.9 21.8 43.3 26.0 31.4 20.0 37.0 20.1 28.4 71.9 62.6 77.0 64.6 70.4 67.2 66.5 61.2 68.7 48.2 65.5 48.3 59.3 59.9 60.4 56.4 69.2 81.0 117.5 5.7 6.0 6.3 7.6 5.4 6.2 6.4 6.4 6.6 6.2 6.1 7.6 36.1 12.8 23.9 12.4 46.4 34.3 50.5 157.7 27.9 17.7 48.4 48.5 31.3 35.8 82.7 44.1 22.9 70.6 70.5 28.1 15.6 79.9 259.2 32.5 41.7 35.7 18.5 35.3 8.1 89.7 103.6 51.3 22.4 41.6 49.4 38.8 30.4 57.5 74.5 11.8 9.0 37.2 89.5 33.6 44.8 63.4 43.8 37.8 46.2 6.5 64.7 35.1 48.4 6.6 16.2 86.7 25.2 35.3 119.9 68.7 37.1 50.4 55.6 24.8 59.2 33.9 54.3 126.4 45.4 26.2 31.1 96.2 47.7 45.8 30.4 62.8 DHCR7 SLOS ENSG00000172893 "7-dehydrocholesterol reductase" Q9UBM7 11 71428193-71452868 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 161.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 77.9;Granulosa cells: 81.3;Hepatocytes: 156.1;Theca cells: 103.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044280 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "HPA044280: AB_10794893" "unprognostic (1.76e-1)" "unprognostic (1.50e-3)" "unprognostic (1.32e-2)" "unprognostic (7.16e-3)" "unprognostic (2.69e-1)" "unprognostic (2.18e-3)" "unprognostic (8.57e-3)" "unprognostic (3.02e-2)" "unprognostic (4.91e-2)" "unprognostic (1.13e-1)" "unprognostic (1.08e-2)" "unprognostic (5.45e-2)" "prognostic favorable (6.93e-7)" "unprognostic (1.73e-1)" "unprognostic (1.01e-1)" "unprognostic (8.15e-2)" "prognostic unfavorable (5.67e-4)" 23.7 97.2 28.1 13.0 35.4 46.7 36.3 42.4 37.0 16.2 15.6 21.1 48.1 10.6 59.2 42.2 12.5 8.9 28.8 28.8 35.8 16.3 161.1 21.8 6.0 55.3 38.8 54.4 16.6 24.4 18.4 8.3 55.8 21.6 14.4 8.7 27.8 7.1 13.6 68.2 19.3 9.9 34.4 9.6 19.1 31.0 38.0 4.7 11.9 13.2 9.4 7.9 22.7 58.9 126.4 112.3 106.7 118.9 49.0 75.8 33.7 50.9 134.1 43.1 114.5 419.8 401.5 87.1 79.0 48.6 376.2 235.9 128.8 276.7 44.5 33.5 98.7 33.4 89.3 183.1 127.8 63.7 15.6 89.2 122.1 159.3 108.4 34.6 63.8 112.7 159.6 180.7 43.2 341.1 52.4 72.6 154.1 124.9 67.4 46.9 150.6 377.3 162.3 187.3 144.7 53.9 48.4 157.6 113.9 51.4 153.2 34.5 60.4 11.5 62.4 3.7 61.5 59.3 78.7 95.8 33.8 110.9 48.9 5.6 2.1 1.9 10.5 1.4 12.6 6.5 8.9 9.8 2.8 5.4 11.0 13.0 1.1 5.8 1.5 7.1 6.0 6.9 28.1 35.4 42.4 37.0 28.8 35.8 55.3 38.8 55.8 34.4 38.0 58.9 7.1 3.2 19.1 7.2 7.1 0.8 10.1 77.9 3.4 8.4 21.8 14.9 13.1 15.7 39.2 22.0 12.5 15.5 11.9 9.9 7.9 36.9 0.1 3.9 1.5 11.8 9.5 5.2 3.2 49.9 27.6 12.8 11.7 9.3 0.0 81.3 7.9 156.1 11.9 0.0 4.5 12.3 54.9 3.8 3.3 1.7 8.4 5.6 5.4 1.0 5.8 21.2 4.1 5.0 14.7 26.7 11.5 4.9 10.0 16.5 8.9 3.8 7.6 8.7 13.1 3.9 9.0 0.5 7.0 11.9 1.1 54.2 13.8 103.6 15.0 9.5 DIP2B "FLJ34278, KIAA1463" ENSG00000066084 "Disco interacting protein 2 homolog B" Q9P265 12 50504985-50748657 "Human disease related genes, Predicted intracellular proteins" Neurogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 61.4" "Cell type enhanced" "Detected in many" "Microglial cells: 188.3;Oligodendrocyte precursor cells: 144.8;Oligodendrocytes: 634.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038472, HPA046133, HPA056045" Enhanced Approved "Endoplasmic reticulum" No No "Cluster 14: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 1: K-562 - Erythropoiesis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Endoplasmic reticulum" "HPA038472: AB_2676033, HPA046133: AB_2679551, HPA056045: AB_2683019" "prognostic unfavorable (2.60e-4)" "unprognostic (2.85e-2)" "unprognostic (3.67e-3)" "unprognostic (2.86e-2)" "unprognostic (9.56e-2)" "unprognostic (2.45e-1)" "unprognostic (1.69e-2)" "unprognostic (3.90e-2)" "unprognostic (1.94e-2)" "unprognostic (2.67e-2)" "unprognostic (9.57e-3)" "unprognostic (3.90e-2)" "unprognostic (4.29e-2)" "unprognostic (7.99e-2)" "unprognostic (1.82e-1)" "unprognostic (1.60e-2)" "unprognostic (1.70e-3)" 6.6 8.7 22.8 8.9 46.0 12.1 10.5 35.0 28.2 7.1 6.9 9.5 6.2 6.2 3.4 14.6 4.3 7.0 5.7 22.5 31.0 6.0 11.3 6.7 9.9 36.1 40.0 9.3 7.6 11.0 6.1 10.3 38.0 6.5 10.7 16.4 8.5 4.1 5.1 17.3 6.5 7.1 26.4 14.9 6.9 7.6 37.0 12.9 8.2 6.3 11.7 7.3 8.8 61.4 20.0 12.0 17.9 12.6 10.0 9.7 25.0 11.3 13.1 10.6 8.0 21.8 11.0 13.4 13.4 12.4 10.9 20.5 28.8 21.1 12.6 15.9 10.7 21.3 10.1 27.6 15.7 25.7 12.4 11.0 18.1 11.8 17.1 18.6 20.4 12.0 30.3 12.5 9.4 15.7 19.9 12.9 10.2 11.4 22.0 23.4 17.6 6.4 12.0 15.5 16.9 11.8 28.3 16.4 17.3 20.6 23.0 17.7 21.6 8.6 10.1 7.9 9.3 9.0 16.0 15.4 11.9 11.7 12.0 1.0 1.2 2.7 0.4 1.4 0.6 1.4 0.9 0.3 1.4 2.2 1.6 1.3 4.9 0.5 3.9 0.4 1.0 0.7 22.8 46.0 35.0 28.2 22.5 31.0 36.1 40.0 38.0 26.4 37.0 61.4 15.4 6.4 10.5 74.1 26.3 54.9 30.2 14.7 12.5 31.5 15.0 11.4 9.0 17.2 10.5 9.2 64.6 13.3 9.2 25.2 0.0 10.9 1.4 14.3 12.9 15.5 31.3 13.7 121.1 17.4 17.6 11.2 20.4 15.1 10.8 25.0 15.0 18.2 20.4 11.8 125.3 18.3 10.2 37.4 15.7 3.3 10.2 24.5 16.0 188.3 18.7 14.4 11.3 144.8 634.8 22.0 14.0 10.1 15.4 28.1 8.4 6.7 8.8 31.9 0.0 8.0 10.0 12.4 17.7 34.6 66.9 38.0 13.3 34.3 12.4 24.4 DNAJB11 "EDJ, ERdj3, HEDJ" ENSG00000090520 "DnaJ heat shock protein family (Hsp40) member B11" Q9UBS4 3 186567403-186585800 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010814, HPA017051" Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA 100000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "HPA010814: AB_1078691, HPA017051: AB_1847792" "unprognostic (4.29e-1)" "unprognostic (1.07e-1)" "unprognostic (2.98e-2)" "unprognostic (2.24e-2)" "unprognostic (8.53e-2)" "unprognostic (1.07e-3)" "unprognostic (3.86e-2)" "unprognostic (6.52e-2)" "unprognostic (7.95e-2)" "unprognostic (2.14e-3)" "unprognostic (2.58e-2)" "unprognostic (1.05e-3)" "prognostic unfavorable (3.44e-9)" "unprognostic (1.27e-1)" "unprognostic (1.43e-1)" "unprognostic (2.33e-1)" "unprognostic (1.82e-1)" 36.1 26.3 17.3 51.5 18.8 50.1 28.2 20.1 19.8 30.3 21.0 38.9 35.2 31.5 36.7 33.2 28.7 28.1 42.9 17.9 20.1 33.0 81.8 35.8 34.5 21.1 19.8 20.5 62.3 31.7 27.0 46.2 20.2 23.3 37.2 16.1 34.3 23.1 22.9 23.9 38.4 30.9 19.3 41.7 37.8 27.1 20.0 30.7 53.2 15.8 36.5 40.6 26.1 21.6 154.5 60.5 87.5 150.5 69.6 53.1 142.4 166.5 98.5 138.6 145.9 187.0 100.5 109.4 326.7 113.3 199.6 139.1 96.0 88.0 135.6 123.7 81.7 97.8 57.0 128.8 150.8 116.8 149.0 46.6 85.5 78.0 130.6 76.4 116.7 59.0 55.8 263.9 93.6 117.4 77.6 85.7 83.1 211.8 76.3 78.1 96.8 187.8 87.7 66.4 73.3 101.3 108.2 181.4 123.2 103.2 209.3 177.6 89.5 76.6 97.1 100.7 244.5 202.9 159.0 175.8 102.3 141.6 169.8 37.4 37.3 39.8 44.0 45.9 37.2 37.2 22.9 36.5 46.2 21.8 21.8 29.2 17.2 50.2 35.4 84.8 33.9 38.4 17.3 18.8 20.1 19.8 17.9 20.1 21.1 19.8 20.2 19.3 20.0 21.6 42.2 19.2 20.9 12.1 78.1 145.3 212.5 104.3 48.9 22.9 38.3 22.7 152.0 67.2 61.4 14.7 18.8 88.7 75.0 93.5 3.9 109.2 41.5 58.2 44.9 63.6 142.1 37.6 10.8 85.7 173.0 63.3 41.3 77.5 54.7 29.4 61.1 105.0 149.4 23.5 11.6 122.8 67.1 65.3 130.3 10.8 31.4 59.4 103.2 14.0 33.3 48.5 63.8 12.1 24.5 86.9 88.2 25.9 251.1 136.6 74.6 18.9 47.3 28.4 65.7 63.7 61.3 190.6 100.7 51.1 112.2 195.1 61.7 28.4 106.8 155.8 DNAJC1 "DNAJL1, ERdj1, MTJ1" ENSG00000136770 "DnaJ heat shock protein family (Hsp40) member C1" Q96KC8 10 21756548-22003769 "Predicted membrane proteins, Transcription factors" "Chaperone, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013432 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Endoplasmic reticulum" "HPA013432: AB_1847797" "unprognostic (7.00e-2)" "unprognostic (9.81e-2)" "unprognostic (3.61e-1)" "unprognostic (5.12e-2)" "unprognostic (5.51e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (1.96e-5)" "unprognostic (3.81e-2)" "unprognostic (1.21e-1)" "unprognostic (3.46e-2)" "unprognostic (1.09e-1)" "unprognostic (9.36e-2)" "prognostic favorable (2.33e-4)" "unprognostic (4.44e-3)" "unprognostic (4.88e-2)" "unprognostic (1.45e-2)" "unprognostic (2.22e-2)" 17.6 16.9 9.9 16.3 11.2 18.3 20.0 10.6 13.1 17.8 15.0 20.6 28.3 15.5 13.4 16.3 14.2 17.7 15.8 9.0 12.9 23.0 36.9 24.0 15.6 12.1 11.1 14.0 38.5 45.6 19.6 19.9 12.4 23.7 18.7 7.1 40.7 16.3 12.7 14.3 22.4 15.8 11.5 15.2 28.6 9.4 11.3 13.1 29.0 11.2 13.0 26.5 15.2 12.7 38.5 24.5 53.9 20.1 49.3 34.9 23.4 50.9 22.1 20.8 32.7 33.8 33.1 16.9 21.9 31.2 31.2 36.1 12.3 25.7 11.5 88.6 41.1 40.3 18.8 20.3 119.5 3.0 16.5 35.8 46.5 24.7 28.3 30.4 27.8 16.4 42.7 93.6 23.8 39.2 9.6 12.9 7.1 33.2 20.3 13.8 18.8 62.3 29.1 9.1 11.3 17.1 37.7 62.2 38.1 58.7 19.8 42.8 42.7 20.3 43.5 34.4 29.3 29.8 10.0 11.7 30.3 126.1 12.3 11.8 16.6 7.0 36.2 16.6 36.5 8.4 20.2 29.1 15.3 12.3 12.9 16.5 9.3 34.2 30.9 39.6 15.8 15.0 9.9 11.2 10.6 13.1 9.0 12.9 12.1 11.1 12.4 11.5 11.3 12.7 56.4 35.3 26.9 73.4 46.7 38.7 64.8 26.6 30.1 27.9 67.9 76.1 16.9 57.2 31.0 31.3 45.9 16.7 92.9 52.4 27.4 73.6 47.6 40.9 74.6 54.7 38.3 49.0 134.4 74.2 92.6 67.4 59.7 58.3 41.8 14.3 52.8 84.5 55.0 38.7 77.1 75.8 28.5 43.7 52.5 19.6 94.8 44.2 67.6 112.4 46.9 37.4 99.9 91.5 137.7 80.6 49.2 67.0 202.7 71.2 57.9 80.1 23.9 149.1 59.2 49.3 56.7 232.2 109.5 45.3 44.2 35.3 81.5 41.0 55.8 71.9 DNAJC3 "ERdj6, HP58, P58, p58(IPK), P58IPK, PRKRI" ENSG00000102580 "DnaJ heat shock protein family (Hsp40) member C3" Q13217 13 95677139-95794988 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Antiviral defense, Stress response, Translation regulation, Unfolded protein response" "Chaperone, Repressor" "Deafness, Diabetes mellitus, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039336, HPA041326" Uncertain Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA 4900000 "Cluster 49: Eosinophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "HPA039336: AB_2676451, HPA041326: AB_2677412" "unprognostic (1.44e-2)" "unprognostic (8.08e-2)" "unprognostic (2.12e-2)" "prognostic favorable (3.47e-5)" "unprognostic (8.18e-2)" "unprognostic (5.78e-2)" "unprognostic (1.09e-1)" "unprognostic (2.19e-2)" "unprognostic (1.31e-1)" "unprognostic (2.45e-1)" "unprognostic (1.20e-1)" "unprognostic (1.64e-1)" "unprognostic (9.69e-2)" "unprognostic (7.19e-2)" "unprognostic (3.37e-2)" "unprognostic (8.30e-3)" "unprognostic (8.18e-2)" 21.0 20.0 10.7 22.5 13.0 45.6 21.3 13.0 11.4 35.1 22.3 25.2 23.8 20.4 38.9 15.9 20.4 22.0 16.6 10.0 14.1 25.5 41.8 22.9 15.0 15.1 12.5 15.8 36.0 24.4 16.2 24.7 15.5 34.5 26.4 9.9 36.3 26.0 9.3 10.9 24.0 22.3 13.4 19.8 28.8 12.7 14.6 11.3 52.8 11.2 17.8 22.1 11.9 16.4 32.4 18.0 14.2 40.7 57.7 28.6 42.6 44.6 40.3 20.2 18.4 22.7 66.5 29.5 41.5 45.0 28.5 32.3 18.7 34.1 30.7 28.8 8.4 40.7 24.6 36.5 79.1 49.8 51.6 34.3 35.7 29.7 68.2 36.9 44.4 13.2 13.9 0.3 34.4 13.1 17.0 17.8 10.6 75.2 13.9 17.1 24.8 22.9 44.9 39.5 8.2 15.6 31.6 74.9 22.5 32.4 37.3 54.6 50.8 39.0 13.3 26.2 23.3 60.6 28.4 13.4 65.6 29.6 54.9 64.7 25.5 86.2 23.9 32.1 25.3 11.2 19.6 20.1 17.2 9.0 13.7 18.7 77.1 22.8 36.0 45.9 13.4 15.7 10.7 13.0 13.0 11.4 10.0 14.1 15.1 12.5 15.5 13.4 14.6 16.4 81.7 80.1 71.3 47.3 61.1 94.1 88.5 81.1 33.6 25.7 65.2 35.9 58.2 81.5 83.4 47.8 27.1 57.1 109.6 69.0 21.5 98.8 160.5 58.0 87.5 64.8 41.9 33.7 30.1 118.7 135.5 99.6 56.6 94.5 67.8 34.4 68.6 140.7 78.8 25.2 37.3 84.9 69.2 70.5 130.2 33.6 71.7 82.0 119.2 47.8 63.1 38.7 51.5 53.3 58.9 97.6 52.4 75.6 214.3 151.2 58.1 71.1 96.7 19.6 92.1 80.8 104.5 47.1 79.9 38.1 92.9 189.8 67.0 53.3 63.8 124.4 DUSP9 "MKP-4, MKP4" ENSG00000130829 "Dual specificity phosphatase 9" Q99956 X 153642492-153651326 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "kidney: 56.9;placenta: 72.6" "Group enriched" "Detected in some" 14 "Cytotrophoblasts: 1171.5;Distal tubular cells: 727.8;Syncytiotrophoblasts: 1735.1" "Cancer enhanced" "Detected in many" "liver cancer: 10.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 9 "Hep G2: 372.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA003336 Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 47: Cytotrophoblasts - Unknown function" "Endoplasmic reticulum" "HPA003336: AB_1078709" "unprognostic (4.64e-2)" "unprognostic (6.48e-2)" "unprognostic (4.87e-2)" "prognostic unfavorable (1.60e-4)" "unprognostic (1.52e-2)" "unprognostic (2.74e-3)" "unprognostic (9.36e-3)" "unprognostic (6.15e-2)" "unprognostic (2.81e-1)" "unprognostic (3.03e-1)" "unprognostic (1.29e-2)" "unprognostic (1.38e-2)" "unprognostic (2.68e-7)" "unprognostic (4.49e-2)" "unprognostic (2.08e-1)" "unprognostic (2.77e-2)" "unprognostic (5.52e-2)" 0.2 0.0 4.1 0.0 3.3 0.0 0.2 1.7 3.8 0.1 1.1 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 4.0 1.9 56.9 1.1 0.0 0.0 2.1 2.5 0.8 0.5 0.7 0.0 72.6 2.2 0.1 0.0 0.0 0.5 0.3 0.0 0.1 0.1 0.0 1.9 0.0 0.0 1.6 2.8 0.0 0.0 0.0 0.0 0.7 0.1 2.6 1.6 0.8 0.1 32.6 0.0 0.0 10.3 0.1 0.0 0.0 0.0 6.5 2.0 0.0 15.8 0.0 1.2 7.5 39.9 1.0 0.0 1.1 7.3 0.0 3.0 372.7 0.0 0.0 5.6 0.0 0.5 0.0 0.0 0.0 0.0 0.2 9.7 0.0 0.0 2.1 0.1 0.8 1.1 1.8 14.8 0.0 0.0 0.0 0.1 9.4 0.4 1.2 2.3 2.8 1.6 0.9 0.6 3.9 0.2 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 3.3 1.7 3.8 4.0 1.9 2.1 2.5 2.2 1.9 2.8 2.6 0.0 0.0 0.0 3.6 0.5 0.6 1.0 0.6 2.8 0.0 0.2 3.4 2.3 1.5 0.0 11.0 0.0 1171.5 0.0 0.0 727.8 0.1 0.0 0.1 0.1 3.1 0.0 0.0 0.7 0.0 84.0 6.1 0.0 0.0 0.0 3.8 0.0 0.9 84.2 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.4 0.0 0.8 0.0 3.2 0.4 0.0 0.0 0.0 0.4 0.8 8.9 0.2 0.0 1735.1 0.2 10.8 0.1 1.1 EBP "CDPX2, CHO2, CPX, CPXD" ENSG00000147155 "EBP cholestenol delta-isomerase" Q15125 X 48521799-48528716 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Isomerase "Cataract, Disease variant, Dwarfism, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 328.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 674.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003130 Approved Supported "Endoplasmic reticulum" NA Yes "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "HPA003130: AB_1078717" "unprognostic (1.90e-1)" "unprognostic (2.64e-2)" "unprognostic (2.80e-1)" "unprognostic (6.27e-2)" "unprognostic (3.41e-1)" "unprognostic (1.64e-1)" "unprognostic (1.13e-1)" "unprognostic (1.15e-1)" "unprognostic (1.34e-1)" "unprognostic (1.87e-1)" "unprognostic (4.72e-2)" "unprognostic (1.47e-1)" "unprognostic (5.14e-2)" "unprognostic (4.04e-2)" "unprognostic (5.39e-2)" "unprognostic (4.13e-1)" "unprognostic (1.36e-1)" 10.2 73.3 16.7 17.1 17.2 48.3 17.4 18.5 17.8 19.4 22.0 50.6 85.5 11.0 17.3 41.3 14.3 10.5 32.5 16.8 18.7 44.0 328.5 24.4 18.8 24.4 16.6 12.7 26.0 44.0 7.2 8.2 24.2 40.6 57.5 10.7 25.0 11.7 9.5 27.8 54.2 14.9 15.8 16.9 31.6 14.2 15.9 28.2 14.4 10.6 32.7 14.1 23.3 16.0 224.5 96.4 107.4 77.0 74.5 39.2 50.5 48.2 43.6 64.3 93.9 169.9 382.7 115.9 35.2 41.3 83.5 230.3 217.5 293.8 49.8 85.8 149.7 50.1 115.2 139.3 57.8 179.2 138.2 51.3 108.6 112.9 86.4 22.5 46.5 98.1 77.6 119.5 50.7 163.7 119.1 199.9 118.2 88.3 199.1 93.8 10.3 363.7 175.6 68.8 110.0 59.6 175.4 122.6 31.2 91.5 122.9 71.1 46.6 33.1 56.2 132.9 63.1 47.5 72.1 107.7 78.7 239.7 40.6 96.1 37.7 97.1 129.4 53.4 104.5 71.5 90.5 116.7 53.5 57.2 76.5 99.7 7.3 63.9 57.2 105.4 103.1 93.6 16.7 17.2 18.5 17.8 16.8 18.7 24.4 16.6 24.2 15.8 15.9 16.0 15.2 32.1 49.8 2.9 38.9 37.1 58.2 245.6 23.3 23.8 57.8 26.2 49.9 77.2 116.6 53.3 8.4 55.9 74.5 140.3 39.2 91.7 10.5 30.5 14.7 26.1 30.0 48.8 7.4 239.1 113.0 21.4 36.2 56.5 40.6 41.2 27.1 674.6 65.0 8.4 10.3 96.8 93.6 30.2 36.0 11.8 13.4 31.9 37.4 4.7 34.8 19.3 101.0 5.0 5.1 156.7 137.3 14.7 54.4 46.4 171.9 99.7 34.8 23.3 13.1 12.5 23.6 8.7 22.7 47.6 45.5 37.5 57.1 128.7 149.1 71.1 EBPL EBRP ENSG00000123179 "EBP like" Q9BY08 13 49660674-49691486 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 99.3" "Cell type enhanced" "Detected in all" "Hepatocytes: 305.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049891 Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 30: Non-specific - Translation" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum" "HPA049891: AB_2680937" "unprognostic (1.49e-1)" "unprognostic (1.41e-2)" "unprognostic (4.23e-2)" "unprognostic (3.06e-2)" "unprognostic (2.81e-1)" "unprognostic (8.63e-3)" "unprognostic (3.91e-2)" "unprognostic (1.57e-1)" "unprognostic (6.91e-2)" "prognostic unfavorable (1.38e-4)" "unprognostic (1.63e-2)" "unprognostic (2.67e-2)" "prognostic unfavorable (7.18e-8)" "unprognostic (1.11e-2)" "unprognostic (1.11e-1)" "unprognostic (3.03e-1)" "unprognostic (1.95e-2)" 21.9 59.7 6.6 12.1 6.5 20.0 23.2 7.0 8.9 37.0 7.5 24.1 14.2 20.4 6.6 62.3 25.5 11.1 8.7 6.7 7.3 14.8 99.3 19.1 11.0 6.8 6.8 33.3 47.7 10.5 10.3 11.2 6.9 21.3 16.3 4.4 27.9 13.5 5.2 33.7 14.3 13.3 7.8 14.4 27.5 11.0 7.9 10.3 16.1 2.5 11.0 23.8 47.6 8.4 46.7 34.9 21.0 88.5 26.0 66.4 37.5 48.5 33.1 30.9 25.0 66.8 65.1 57.9 21.6 23.7 27.1 93.7 38.3 47.4 45.0 46.4 126.8 43.7 23.4 83.3 75.2 69.4 35.0 77.7 100.4 25.6 68.1 49.9 53.6 61.5 36.7 23.0 40.2 25.0 27.4 124.8 72.4 153.2 78.2 58.5 11.7 89.0 66.4 15.2 19.5 50.1 18.0 62.1 21.6 21.7 54.4 54.0 24.6 23.4 23.2 20.2 40.7 14.9 41.2 46.7 11.2 68.6 21.6 2.4 3.0 0.8 2.4 3.6 6.8 4.3 4.8 5.0 5.0 5.4 7.1 4.1 6.4 4.1 3.9 3.3 3.7 1.4 6.6 6.5 7.0 8.9 6.7 7.3 6.8 6.8 6.9 7.8 7.9 8.4 75.5 35.3 23.1 9.8 46.5 108.6 157.6 17.4 115.5 7.9 139.8 192.1 5.4 104.4 17.4 23.9 8.4 32.3 25.5 26.5 41.1 61.2 13.3 61.5 90.6 76.8 27.8 65.6 8.0 52.1 37.1 56.9 56.6 50.0 17.8 64.9 78.9 305.3 38.5 1.7 11.6 80.1 8.2 45.8 36.5 10.0 94.1 27.4 46.2 8.4 30.9 23.6 36.0 8.0 5.1 41.0 42.0 70.0 79.3 116.6 16.5 62.3 8.5 8.4 19.7 57.7 52.7 26.9 17.2 208.6 154.6 15.2 40.3 194.2 133.6 108.9 EDEM3 C1orf22 ENSG00000116406 "ER degradation enhancing alpha-mannosidase like protein 3" Q9BZQ6 1 184690237-184754907 "Enzymes, Predicted intracellular proteins" "Unfolded protein response" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025754, HPA025755, HPA027297" Approved Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 27: Mucus-secreting cells - Mucin production" "Endoplasmic reticulum" "HPA025754: AB_1845638, HPA025755: AB_1845639, HPA027297: AB_2672205" "unprognostic (1.74e-1)" "unprognostic (1.64e-2)" "unprognostic (3.08e-2)" "unprognostic (2.67e-2)" "unprognostic (2.30e-1)" "unprognostic (3.10e-2)" "unprognostic (7.52e-3)" "unprognostic (1.82e-1)" "unprognostic (7.06e-2)" "unprognostic (1.66e-1)" "unprognostic (1.66e-1)" "unprognostic (3.53e-2)" "prognostic unfavorable (1.63e-6)" "unprognostic (4.72e-2)" "unprognostic (1.29e-1)" "unprognostic (1.08e-2)" "unprognostic (2.01e-1)" 14.3 12.4 3.8 13.8 4.8 8.2 10.9 6.6 5.1 13.7 4.3 20.6 18.8 8.8 8.0 9.2 6.6 11.7 7.2 4.1 6.5 10.6 20.3 11.2 10.2 4.7 5.7 5.7 15.7 13.0 7.1 20.8 4.6 13.5 24.0 11.4 13.2 8.7 12.2 6.6 16.3 12.0 4.5 10.5 35.8 7.4 5.5 10.8 11.8 11.4 10.7 13.6 5.8 6.3 15.1 11.2 15.0 13.4 53.8 55.0 24.5 29.9 20.7 11.1 11.6 5.9 42.4 10.5 31.8 22.8 11.3 20.1 14.6 15.6 16.4 10.3 11.9 13.8 11.7 8.5 20.7 36.4 19.5 31.6 18.8 27.1 24.2 21.0 30.4 27.4 36.8 47.4 21.6 12.5 29.3 18.8 21.2 34.1 10.2 12.7 11.6 36.2 16.1 10.4 16.9 23.9 14.7 25.2 20.8 24.9 23.7 56.3 36.1 16.1 7.2 34.3 25.5 72.1 29.8 13.6 21.3 40.7 35.6 5.0 3.5 2.2 1.4 3.5 2.5 1.3 2.2 1.7 3.1 0.9 3.0 1.6 3.6 2.2 3.6 1.6 1.5 1.8 3.8 4.8 6.6 5.1 4.1 6.5 4.7 5.7 4.6 4.5 5.5 6.3 35.1 19.2 19.3 41.4 19.9 16.7 8.4 9.8 19.9 26.1 20.4 11.4 16.0 12.8 21.8 14.7 25.0 13.8 13.2 55.1 0.0 14.0 16.0 14.3 21.2 25.9 30.6 32.4 58.2 35.6 10.9 28.0 96.8 17.0 21.0 12.9 19.2 47.0 13.0 21.9 62.8 76.5 2.0 40.1 30.3 7.1 20.5 33.0 19.6 36.5 31.0 7.8 11.3 47.3 61.6 20.0 28.1 18.0 73.6 27.1 21.4 9.7 28.1 15.2 19.7 20.3 18.7 15.0 8.7 18.2 20.5 19.4 24.9 53.8 32.4 19.1 ELAPOR2 "EIG121L, FLJ31340, KIAA1324L" ENSG00000164659 "Endosome-lysosome associated apoptosis and autophagy regulator family member 2" A8MWY0 7 86876906-87059654 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 51.7" "Cell type enhanced" "Detected in some" "Adipocytes: 12.9;Cardiomyocytes: 2.8;Endothelial cells: 2.2;Fibroblasts: 2.3;Smooth muscle cells: 3.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 5 "B-cells: 1.9;NK-cells: 2.3;T-cells: 2.7" "Cell line enhanced" "Detected in many" "AF22: 31.2;hTERT-HME1: 36.0;HUVEC TERT2: 30.8;K-562: 49.6;SCLC-21H: 38.7;SuSa: 33.8;TIME: 36.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044527, HPA076093" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 1: K-562 - Erythropoiesis" "Cluster 24: Non-specific - Transcription regulation" "Endoplasmic reticulum" "HPA044527: AB_10963793, HPA076093: AB_2686776" "unprognostic (2.78e-2)" "unprognostic (9.37e-2)" "unprognostic (1.40e-1)" "unprognostic (4.15e-4)" "unprognostic (3.79e-1)" "unprognostic (4.00e-2)" "unprognostic (1.33e-3)" "unprognostic (1.89e-1)" "unprognostic (1.96e-1)" "unprognostic (2.16e-1)" "unprognostic (2.28e-2)" "unprognostic (6.82e-2)" "unprognostic (8.82e-3)" "unprognostic (3.86e-3)" "unprognostic (1.25e-1)" "unprognostic (4.32e-1)" "unprognostic (1.37e-1)" 10.3 3.6 10.5 2.0 26.6 0.9 4.5 17.1 14.4 3.0 0.0 4.3 1.4 3.5 0.5 3.7 3.2 4.3 4.8 7.7 16.2 2.3 1.2 21.8 3.4 19.3 16.3 2.0 4.6 8.3 3.0 7.8 20.5 6.1 5.4 5.8 2.3 5.0 2.3 2.2 2.4 5.4 15.5 5.8 3.2 3.1 22.9 3.7 5.1 4.0 3.5 5.2 1.6 51.7 1.9 0.0 31.2 0.0 0.4 0.0 8.2 0.7 0.0 0.1 0.0 0.1 0.5 0.3 7.8 0.7 0.3 0.0 3.4 0.0 0.1 7.8 0.7 24.8 8.6 2.9 0.3 0.2 3.1 2.5 0.1 0.0 36.0 0.2 30.8 12.1 49.6 0.8 3.4 9.9 0.7 0.0 17.1 0.1 7.9 0.0 2.2 5.2 3.2 14.3 38.7 28.9 8.5 11.1 3.6 33.8 3.3 0.6 36.5 0.4 11.9 0.3 0.0 17.2 10.9 0.2 9.1 0.0 0.4 0.0 0.0 0.2 0.3 0.0 2.7 0.4 0.9 0.6 0.2 1.9 0.9 0.5 0.0 2.3 0.0 0.4 0.4 0.3 10.5 26.6 17.1 14.4 7.7 16.2 19.3 16.3 20.5 15.5 22.9 51.7 12.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.4 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 ELOVL1 Ssc1 ENSG00000066322 "ELOVL fatty acid elongase 1" Q9BW60 1 43363398-43368074 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033426, HPA056557" Enhanced Supported "Endoplasmic reticulum" NA Yes "Cluster 31: Non-specific - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "Endoplasmic reticulum" "CAB033426: AB_2099896, HPA056557: AB_2683173" "unprognostic (5.23e-2)" "prognostic unfavorable (3.63e-5)" "unprognostic (8.00e-2)" "unprognostic (8.45e-2)" "unprognostic (7.60e-2)" "unprognostic (7.40e-2)" "prognostic unfavorable (2.79e-7)" "unprognostic (4.74e-2)" "unprognostic (1.33e-1)" "unprognostic (4.37e-1)" "prognostic unfavorable (8.51e-4)" "unprognostic (1.83e-1)" "unprognostic (2.88e-2)" "unprognostic (1.41e-2)" "unprognostic (1.28e-1)" "unprognostic (1.73e-1)" "unprognostic (9.00e-2)" 78.5 54.7 77.2 39.8 115.6 52.9 66.6 121.1 116.9 57.1 61.4 63.9 51.6 46.5 30.6 176.6 38.9 42.4 47.2 76.8 93.2 59.7 45.8 59.6 40.1 152.0 110.1 28.9 55.4 46.2 27.2 51.0 140.7 58.7 48.6 8.4 72.7 48.8 24.1 201.9 55.4 50.8 114.8 57.1 70.6 18.6 107.7 22.2 66.8 28.0 55.7 68.5 86.8 165.7 108.0 119.5 22.6 44.8 148.4 138.2 70.2 125.2 154.5 153.5 122.4 105.9 182.5 73.9 94.3 193.6 130.3 119.4 79.7 152.2 93.2 94.6 53.9 96.6 77.3 77.1 128.2 84.2 98.0 106.2 168.2 180.9 198.4 114.8 155.0 27.7 68.1 54.8 178.5 79.5 19.9 69.5 33.5 136.9 120.2 43.6 59.9 89.7 195.5 128.7 27.4 28.8 73.7 258.4 105.8 66.8 121.2 82.4 132.2 129.7 82.5 161.2 161.3 26.6 31.2 35.4 127.8 85.2 120.1 134.9 189.6 172.7 105.1 180.0 93.4 109.0 98.4 103.2 212.8 94.2 63.5 88.0 133.0 114.7 179.6 148.8 113.8 203.1 77.2 115.6 121.1 116.9 76.8 93.2 152.0 110.1 140.7 114.8 107.7 165.7 44.0 19.2 12.5 7.5 28.1 15.6 25.9 61.1 29.6 5.7 60.3 37.5 4.7 34.3 40.2 40.5 10.4 93.4 36.0 114.0 7.9 91.5 3.4 22.9 26.3 43.6 19.2 67.8 3.8 100.1 127.4 26.1 48.4 45.2 21.0 52.6 24.7 16.7 74.9 3.3 3.4 33.8 46.8 46.3 37.5 4.6 20.2 41.5 12.4 7.5 92.5 13.7 32.0 3.0 66.1 133.3 63.9 25.6 19.0 44.7 66.0 23.3 14.5 9.5 19.7 10.0 39.7 8.4 11.2 70.1 31.0 95.9 31.5 50.8 47.2 49.2 ELOVL5 "dJ483K16.1, HELO1, SCA38" ENSG00000012660 "ELOVL fatty acid elongase 5" Q9NYP7 6 53267398-53349179 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017042, HPA047752, HPA054197" Enhanced Enhanced "Endoplasmic reticulum" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 35: Glandular cells - Unknown function" "Endoplasmic reticulum" "CAB017042: , HPA047752: AB_2680147, HPA054197: AB_2682413" "unprognostic (7.33e-2)" "unprognostic (5.80e-2)" "unprognostic (1.04e-1)" "unprognostic (1.92e-2)" "unprognostic (1.16e-1)" "unprognostic (5.01e-2)" "unprognostic (3.06e-1)" "unprognostic (2.19e-1)" "unprognostic (4.38e-2)" "unprognostic (1.43e-2)" "unprognostic (3.23e-1)" "unprognostic (6.40e-2)" "prognostic unfavorable (1.94e-6)" "unprognostic (1.58e-1)" "unprognostic (5.12e-2)" "prognostic unfavorable (6.80e-4)" "unprognostic (2.76e-2)" 242.4 134.7 51.3 74.9 67.0 114.6 199.2 74.6 79.2 48.9 49.4 40.0 28.3 39.8 49.7 28.4 46.0 51.3 37.8 50.8 65.3 38.9 108.9 68.4 106.7 80.7 69.0 32.3 15.4 24.3 28.5 40.2 74.5 128.0 18.3 36.5 24.8 103.0 9.9 32.9 47.5 52.4 67.7 56.1 22.8 82.5 65.8 107.3 45.1 19.5 102.4 67.1 27.0 98.9 137.2 98.1 168.0 309.0 436.0 250.8 71.3 155.8 174.2 123.2 171.5 87.4 154.5 154.4 110.3 163.3 193.1 78.9 168.0 142.6 183.7 131.2 117.5 153.1 85.0 122.9 239.0 122.2 107.2 233.6 109.8 123.6 153.9 124.5 139.1 301.4 194.2 87.3 90.3 14.9 364.4 107.9 91.2 5.2 73.6 139.9 115.3 54.3 232.7 80.6 155.7 107.1 129.3 66.9 135.2 108.7 152.3 112.9 133.0 134.7 118.5 242.2 208.8 72.8 72.1 116.2 70.2 173.6 97.8 47.6 49.2 183.7 34.9 34.9 56.5 88.4 58.1 42.7 77.9 101.5 27.8 26.3 261.5 36.7 45.0 20.4 110.0 50.6 51.3 67.0 74.6 79.2 50.8 65.3 80.7 69.0 74.5 67.7 65.8 98.9 48.6 80.1 50.7 75.4 118.3 52.4 108.2 36.8 44.3 11.6 177.3 70.9 23.3 21.5 40.2 12.9 2.1 25.3 55.5 2.1 15.6 34.9 94.2 37.4 53.2 54.4 25.0 77.0 25.8 36.1 58.2 54.8 3.1 66.4 99.0 28.4 39.3 88.7 35.5 8.4 29.8 1.6 16.2 57.3 114.6 181.0 20.8 55.5 48.0 39.4 53.5 83.2 39.1 49.3 111.2 27.8 1.4 32.0 45.2 169.2 21.9 48.4 58.5 6.0 65.7 27.3 77.5 27.0 18.9 35.7 60.9 31.2 97.2 60.0 4.4 73.4 ERLIN1 "C10orf69, Erlin-1, KE04, SPFH1, SPG62" ENSG00000107566 "ER lipid raft associated 1" O75477 10 100150094-100186033 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 114.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 77.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011252 Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 32: U-937 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Endoplasmic reticulum" "HPA011252: AB_1853965" "unprognostic (3.22e-1)" "unprognostic (1.31e-1)" "unprognostic (1.57e-1)" "unprognostic (6.98e-3)" "unprognostic (2.69e-1)" "unprognostic (1.70e-2)" "unprognostic (2.30e-1)" "prognostic unfavorable (7.63e-4)" "unprognostic (1.26e-1)" "unprognostic (9.68e-2)" "unprognostic (1.99e-3)" "unprognostic (9.09e-2)" "unprognostic (1.32e-3)" "unprognostic (6.10e-3)" "unprognostic (1.76e-1)" "unprognostic (2.97e-1)" "unprognostic (1.93e-1)" 29.4 14.2 8.6 21.4 10.5 76.2 21.4 9.5 10.1 27.5 10.3 37.0 40.4 21.8 17.6 32.8 31.6 16.3 11.0 9.6 9.4 27.2 114.1 19.1 14.5 8.6 8.2 30.4 19.2 19.4 5.4 42.2 9.0 17.7 38.2 10.8 15.1 16.4 8.6 22.5 30.2 22.4 8.8 16.6 36.8 28.0 9.0 15.6 26.2 13.6 21.2 28.6 19.1 9.7 97.4 95.3 46.9 86.3 113.5 107.9 96.8 148.7 138.3 120.2 137.5 64.0 109.9 42.6 59.7 139.9 100.5 98.5 42.6 90.0 164.1 26.1 38.8 36.7 38.5 83.5 47.6 128.4 39.4 62.6 53.6 105.8 129.2 114.9 90.1 43.5 36.8 25.2 130.2 40.7 33.5 65.9 33.8 66.2 40.4 28.3 77.2 31.6 53.9 37.6 19.1 31.1 85.6 23.6 56.0 53.8 59.3 109.0 101.7 118.7 92.4 72.4 160.8 19.6 35.2 57.1 105.6 204.8 60.6 8.1 20.4 24.4 10.5 15.1 9.3 7.4 7.9 8.6 16.3 6.7 8.1 10.9 15.0 9.9 11.9 4.1 5.6 9.7 8.6 10.5 9.5 10.1 9.6 9.4 8.6 8.2 9.0 8.8 9.0 9.7 28.2 0.0 11.5 5.2 6.4 15.8 11.3 16.1 12.5 4.6 13.4 12.3 4.8 5.7 14.6 14.7 6.2 20.6 6.4 31.5 0.0 9.9 28.9 16.3 19.5 18.8 13.2 19.1 16.2 10.9 62.7 17.1 20.4 20.9 8.2 19.7 13.6 77.6 14.3 3.3 14.8 27.5 0.0 14.4 7.2 12.9 15.2 12.9 10.6 12.2 13.3 5.9 6.2 15.6 21.0 9.5 19.8 7.9 4.7 12.7 25.6 12.6 30.2 6.2 0.0 14.3 11.8 50.9 15.4 20.6 20.3 24.8 6.6 19.6 27.6 15.6 ERLIN2 "C8orf2, Erlin-2, NET32, SPFH2, SPG18" ENSG00000147475 "ER lipid raft associated 2" O94905 8 37736601-37758422 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002025, CAB014894" Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" "Endoplasmic reticulum" "CAB014894: , HPA002025: AB_1080077" "unprognostic (5.82e-3)" "unprognostic (2.45e-1)" "prognostic favorable (5.16e-4)" "unprognostic (1.08e-2)" "prognostic unfavorable (4.51e-4)" "unprognostic (3.39e-2)" "unprognostic (1.89e-1)" "unprognostic (3.77e-2)" "unprognostic (6.67e-2)" "unprognostic (4.21e-2)" "unprognostic (1.88e-2)" "unprognostic (1.78e-3)" "prognostic favorable (6.67e-6)" "unprognostic (4.78e-2)" "unprognostic (2.83e-1)" "unprognostic (3.43e-1)" "unprognostic (2.33e-1)" 20.3 17.8 15.7 14.6 17.3 14.4 25.0 16.5 16.8 20.0 27.2 24.2 17.7 21.2 32.3 17.9 30.1 19.8 17.8 14.2 16.3 40.4 40.8 15.5 11.5 18.0 18.5 30.8 26.2 41.4 8.3 21.2 17.7 25.4 25.0 21.6 29.4 23.8 18.9 15.3 23.6 19.5 17.9 14.6 24.9 17.0 15.6 14.7 46.5 14.1 12.6 16.8 10.3 18.6 39.0 38.5 43.0 31.4 47.3 33.9 47.2 59.1 51.9 31.8 33.2 20.1 50.8 18.9 95.8 63.4 30.3 41.4 31.2 48.4 46.8 11.2 24.2 27.8 22.7 22.7 31.5 17.8 34.1 43.3 49.1 46.3 48.1 39.6 30.7 17.2 51.1 17.7 47.4 18.3 25.8 14.7 45.9 53.8 17.7 17.9 29.9 15.2 42.8 41.9 7.7 20.7 39.3 12.6 35.6 50.1 62.0 27.1 31.1 30.9 26.4 56.8 31.1 24.3 41.0 24.2 55.0 28.4 40.7 1.3 6.5 13.4 4.4 7.0 3.6 4.5 2.7 3.5 5.4 2.3 4.1 3.8 6.1 2.5 9.6 7.6 5.5 3.1 15.7 17.3 16.5 16.8 14.2 16.3 18.0 18.5 17.7 17.9 15.6 18.6 14.7 12.8 14.3 21.5 7.1 9.7 10.0 18.5 13.1 25.2 24.9 20.7 30.2 25.8 22.8 33.1 20.9 17.9 6.0 19.0 9.8 23.8 21.3 31.3 18.5 13.6 11.4 8.0 3.7 22.1 27.0 18.8 17.3 27.8 3.8 14.4 17.5 41.0 20.6 16.8 6.4 24.3 20.3 23.9 6.6 16.8 11.8 16.1 14.2 7.5 12.3 23.5 5.2 11.6 16.7 18.8 17.4 17.7 16.8 15.2 25.4 19.8 47.6 18.7 19.7 19.1 14.8 47.4 18.5 21.9 7.4 15.7 7.1 12.9 25.4 12.8 ESYT1 "FAM62A, KIAA0747, MBC2" ENSG00000139641 "Extended synaptotagmin 1" Q9BSJ8 12 56118250-56144674 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016858, HPA076926" Approved Supported "Endoplasmic reticulum" NA NA 720000 "Cluster 2: Granulocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Endoplasmic reticulum" "HPA016858: AB_1848404, HPA076926: AB_2686819" "unprognostic (5.02e-2)" "unprognostic (3.62e-2)" "unprognostic (6.26e-3)" "unprognostic (1.87e-1)" "unprognostic (3.28e-2)" "unprognostic (8.44e-2)" "unprognostic (5.41e-2)" "unprognostic (1.55e-1)" "unprognostic (1.39e-2)" "unprognostic (1.77e-1)" "unprognostic (6.85e-3)" "unprognostic (1.29e-1)" "prognostic favorable (3.86e-4)" "unprognostic (3.04e-2)" "unprognostic (8.43e-3)" "unprognostic (1.52e-2)" "unprognostic (3.98e-2)" 107.9 39.3 15.2 38.5 14.4 18.7 72.7 18.5 18.9 36.6 19.8 45.9 17.2 53.4 22.2 29.2 47.1 27.8 24.5 13.5 23.0 26.8 46.7 45.0 45.9 34.2 21.7 38.8 39.5 40.7 11.7 38.7 36.2 30.5 36.2 8.9 28.0 47.2 54.2 26.1 30.7 74.4 22.5 37.2 29.3 12.1 23.6 36.6 27.8 33.3 49.8 44.7 32.3 24.0 107.0 78.1 62.2 158.2 90.8 67.3 53.4 117.4 129.3 136.2 94.4 72.4 114.3 40.8 92.2 201.3 50.7 118.7 73.7 120.4 121.6 58.8 54.2 244.7 56.0 58.5 125.9 193.2 371.6 76.7 125.5 147.1 81.3 145.3 117.8 39.2 153.6 263.9 124.4 81.2 70.4 116.4 78.9 44.6 102.5 105.4 85.0 107.3 113.7 89.0 52.4 54.8 174.1 52.9 80.5 71.3 111.1 128.4 154.5 104.8 94.7 59.7 85.7 62.3 99.0 58.7 97.3 79.6 111.7 423.2 37.4 423.0 127.2 69.4 157.2 62.4 129.4 129.5 87.2 48.2 102.3 120.2 9.3 84.2 85.6 29.7 139.6 177.8 15.2 14.4 18.5 18.9 13.5 23.0 34.2 21.7 36.2 22.5 23.6 24.0 44.4 9.6 9.3 4.6 25.9 16.3 19.8 23.5 14.2 5.5 20.5 21.3 8.2 14.3 12.9 31.3 10.4 31.9 22.3 6.1 0.0 36.8 2.0 20.5 15.1 28.2 25.2 17.9 10.2 26.8 18.1 17.6 9.2 19.3 62.7 24.7 27.1 37.8 46.4 0.0 7.1 12.0 22.4 21.3 24.8 2.1 17.4 22.9 35.6 6.5 50.6 5.7 60.8 2.0 4.1 26.2 3.5 25.2 18.5 19.9 2.2 4.4 10.7 5.9 52.6 14.3 22.0 3.9 2.9 18.0 11.9 37.9 40.3 12.5 10.8 12.7 FAM234B KIAA1467 ENSG00000084444 "Family with sequence similarity 234 member B" A2RU67 12 13044381-13142521 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 22.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 29.8;Breast glandular cells: 16.8;Collecting duct cells: 18.4;Erythroid cells: 13.2;Spermatogonia: 13.7" "Cancer enhanced" "Detected in all" "breast cancer: 16.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010803, HPA010850" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 58: Brain - Synaptic function" "Cluster 12: NES - Nervous system development" "Cluster 30: Mammary glandular cells - Lactation" "Endoplasmic reticulum" "HPA010803: AB_1079200, HPA010850: AB_2732402" "unprognostic (1.85e-3)" "unprognostic (1.99e-1)" "unprognostic (1.93e-3)" "unprognostic (2.92e-2)" "unprognostic (1.29e-1)" "unprognostic (8.03e-3)" "unprognostic (3.34e-2)" "unprognostic (1.37e-1)" "unprognostic (9.55e-2)" "unprognostic (3.40e-2)" "unprognostic (3.62e-2)" "unprognostic (1.63e-1)" "unprognostic (1.85e-3)" "unprognostic (5.22e-2)" "unprognostic (1.06e-1)" "unprognostic (4.06e-3)" "unprognostic (7.62e-2)" 3.3 2.5 14.1 1.6 14.7 3.0 16.4 9.2 22.9 2.3 4.5 1.5 1.8 2.5 3.1 2.0 2.9 1.6 1.8 15.5 16.1 5.4 2.2 2.7 1.6 10.5 10.7 2.5 2.6 3.3 5.1 5.7 11.5 6.2 1.1 17.6 2.7 2.4 2.2 12.7 1.8 2.3 8.1 2.2 1.6 5.6 11.7 2.3 8.6 1.7 1.5 2.5 2.6 13.4 3.6 3.6 10.9 7.7 8.3 8.0 8.4 2.4 2.8 5.3 10.4 3.8 5.3 14.7 2.9 2.9 9.4 5.4 13.9 2.6 11.0 1.7 7.7 8.7 4.1 3.0 4.4 7.6 4.7 6.3 5.5 7.8 5.9 8.0 7.2 10.2 2.2 5.1 5.8 12.2 6.5 4.8 14.3 2.8 2.0 8.5 14.0 1.6 3.3 8.9 15.0 4.9 5.3 3.5 4.3 18.5 4.4 4.2 3.5 3.5 5.8 6.5 2.6 2.8 3.9 9.4 11.1 3.4 4.4 0.2 1.4 1.1 1.3 2.6 1.8 2.4 1.5 1.3 1.2 3.4 2.1 2.3 0.3 1.5 4.2 2.3 1.2 0.7 14.1 14.7 9.2 22.9 15.5 16.1 10.5 10.7 11.5 8.1 11.7 13.4 5.4 3.2 3.3 0.0 2.2 0.0 2.1 0.0 1.2 29.8 16.8 3.6 0.0 2.8 0.0 18.4 2.1 9.6 1.0 0.0 1.9 2.0 9.3 1.1 1.0 3.2 12.2 13.2 0.0 1.3 3.4 1.9 0.5 1.5 0.0 2.0 5.0 2.3 3.6 3.3 0.0 0.8 0.0 1.6 0.0 3.6 5.6 1.5 0.0 0.0 2.3 4.2 1.0 0.0 0.0 1.1 1.2 5.3 1.9 3.3 2.6 1.2 0.0 3.3 0.0 1.6 1.3 9.2 13.7 2.2 0.0 3.6 1.3 1.2 0.9 1.5 FBLN1 FBLN ENSG00000077942 "Fibulin 1" P23142 22 45502238-45601135 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 666.3;Endometrial stromal cells: 628.2;Extravillous trophoblasts: 651.6;Fibroblasts: 1506.5;Syncytiotrophoblasts: 1215.9" "Cancer enhanced" "Detected in all" "endometrial cancer: 199.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 1839.4;ASC TERT1: 809.8;BJ: 1029.3;BJ hTERT+: 1615.9;HSkMC: 1345.8;RT4: 1485.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001612, HPA001613, CAB004393, CAB068187" Enhanced Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 21000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB004393: AB_671972, CAB068187: AB_2665634, HPA001612: AB_1078825, HPA001613: AB_1078824" "unprognostic (6.62e-2)" "unprognostic (2.47e-2)" "unprognostic (1.64e-1)" "prognostic favorable (9.28e-4)" "unprognostic (1.26e-3)" "unprognostic (4.82e-2)" "unprognostic (9.79e-3)" "unprognostic (2.49e-1)" "unprognostic (6.30e-2)" "unprognostic (3.86e-2)" "unprognostic (2.84e-2)" "unprognostic (3.30e-2)" "prognostic unfavorable (3.02e-10)" "unprognostic (1.08e-3)" "unprognostic (1.46e-1)" "unprognostic (1.29e-2)" "unprognostic (3.64e-2)" 359.3 123.1 17.3 72.3 29.5 1.7 318.2 27.8 27.5 1131.0 802.4 200.7 75.5 410.6 126.0 305.8 497.6 676.1 773.7 47.0 11.9 61.3 15.7 414.9 16.1 21.8 24.5 214.1 106.3 216.9 90.3 505.7 23.1 466.8 83.6 3.1 121.2 158.5 36.0 296.3 174.5 180.3 15.9 24.9 269.1 21.9 24.7 20.5 195.3 47.5 13.0 704.6 940.5 14.6 17.7 41.6 122.9 258.0 1839.4 809.8 559.8 1029.3 1615.9 89.8 33.8 179.2 5.2 0.4 42.8 38.6 2.5 90.9 78.0 2.7 10.8 0.9 21.0 0.4 209.4 121.5 243.2 1.0 1.0 1345.8 15.8 89.6 32.7 1.8 0.2 1.4 0.9 2.1 63.3 2.4 0.8 3.2 173.8 3.7 15.4 1.4 0.9 2.1 41.1 1485.2 8.7 162.7 127.5 589.6 0.6 344.3 3.7 5.4 8.0 17.4 109.3 465.8 1.0 1.6 0.8 1.4 1.2 1.0 43.5 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.5 0.1 0.1 0.1 0.2 0.0 2.4 1.2 0.0 0.1 17.3 29.5 27.8 27.5 47.0 11.9 21.8 24.5 23.1 15.9 24.7 14.6 34.4 6.4 1.3 34.3 1.2 170.9 113.4 54.8 21.1 0.1 5.3 11.6 20.1 10.0 28.3 1.8 0.0 666.3 1.6 0.1 0.0 1.3 10.5 61.5 628.2 34.5 0.0 0.0 0.5 0.2 651.6 1506.5 38.7 256.5 1.3 29.0 22.1 0.6 82.4 0.0 0.8 0.3 6.1 0.0 222.9 25.4 92.2 11.4 170.7 41.2 0.0 0.1 0.0 0.0 0.4 1.0 0.1 30.5 4.5 47.4 0.0 0.3 10.2 0.6 118.3 37.1 81.5 42.2 68.7 23.8 130.3 1215.9 18.2 2.3 0.4 86.9 FDFT1 SQS ENSG00000079459 "Farnesyl-diphosphate farnesyltransferase 1" P37268 8 11795573-11839304 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 479.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Daudi: 133.1;RPMI-8226: 361.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008874 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 37: B-cells - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 25: RPMI-8226 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Endoplasmic reticulum" "HPA008874: AB_1078844" "unprognostic (2.33e-1)" "unprognostic (2.60e-1)" "prognostic favorable (4.92e-5)" "unprognostic (1.29e-2)" "unprognostic (1.46e-2)" "unprognostic (1.71e-1)" "unprognostic (8.10e-2)" "unprognostic (1.01e-1)" "unprognostic (2.39e-1)" "unprognostic (2.45e-1)" "unprognostic (2.31e-3)" "unprognostic (2.57e-1)" "prognostic favorable (6.59e-9)" "unprognostic (2.28e-1)" "unprognostic (4.06e-2)" "unprognostic (3.86e-1)" "unprognostic (2.06e-1)" 69.1 126.7 8.2 6.7 14.9 15.0 69.5 13.1 11.6 93.3 7.4 113.4 6.7 80.2 2.9 165.7 59.4 3.2 62.9 10.0 11.7 71.3 118.3 88.0 6.0 29.9 14.1 66.9 58.6 2.0 51.2 4.2 23.1 64.5 5.8 5.4 141.7 3.1 160.3 129.0 92.2 4.9 15.4 50.4 113.2 118.7 15.3 3.2 45.9 6.9 4.5 70.4 107.8 31.9 19.1 8.1 28.8 19.4 3.8 5.7 10.9 19.2 10.6 7.4 8.6 8.1 14.1 133.1 3.9 3.2 34.6 17.8 10.6 24.7 8.2 13.1 17.2 9.6 11.1 21.7 7.4 5.5 13.0 11.2 6.0 13.2 4.7 5.3 2.1 24.5 12.1 60.0 4.6 11.1 16.7 12.9 27.1 9.0 5.3 14.9 11.3 361.0 11.9 61.5 9.6 11.2 4.3 11.2 35.9 12.3 11.6 6.8 11.3 5.1 21.6 3.1 5.8 17.0 30.2 26.3 7.5 18.7 19.7 52.1 19.5 25.5 23.1 23.6 20.7 60.5 25.3 24.5 29.1 45.6 25.7 23.3 22.3 26.7 15.1 27.9 45.7 43.9 8.2 14.9 13.1 11.6 10.0 11.7 29.9 14.1 23.1 15.4 15.3 31.9 31.1 54.5 164.1 67.6 78.0 52.5 94.0 479.6 87.6 17.7 79.6 49.8 78.5 101.5 325.8 79.1 14.6 266.2 49.4 134.8 88.0 165.6 294.4 55.0 20.9 45.2 79.1 113.2 29.3 284.4 153.3 37.1 64.2 68.1 57.0 86.2 22.1 221.8 94.1 11.8 25.6 117.4 284.8 41.9 32.2 228.8 77.0 54.3 101.4 38.4 97.1 61.9 55.6 30.2 95.6 163.6 108.4 53.4 50.0 101.3 87.0 74.9 142.6 21.0 52.6 13.8 74.4 215.5 76.1 112.5 88.8 175.0 55.7 131.4 100.4 167.2 FGA ENSG00000171560 "Fibrinogen alpha chain" P02671 4 154583128-154590745 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Adaptive immunity, Blood coagulation, Hemostasis, Immunity, Innate immunity" "Amyloidosis, Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 388 "liver: 18396.9" "Cell type enriched" "Detected in some" 41 "Hepatocytes: 17365.8" "Cancer enriched" "Detected in many" 43 "liver cancer: 2431.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "Hep G2: 429.3" "Not detected" "Not detected" "Not detected" "Not detected" "CAB016776, HPA051370, HPA064755" Supported Enhanced "Endoplasmic reticulum" "Secreted to blood" NA NA 407000000 140000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "CAB016776: , HPA051370: AB_2681458, HPA064755: AB_2685345" "unprognostic (5.95e-2)" "unprognostic (6.25e-2)" "unprognostic (2.02e-1)" "unprognostic (5.68e-2)" "prognostic favorable (7.33e-4)" "unprognostic (1.29e-3)" "unprognostic (1.84e-1)" "prognostic unfavorable (4.23e-6)" "unprognostic (4.20e-1)" "unprognostic (1.41e-1)" 2.1 1.3 0.0 0.0 0.0 0.0 1.0 0.0 0.0 1.5 0.0 0.5 0.0 0.6 0.6 0.7 0.9 13.2 1.2 0.0 0.0 18.8 18396.9 5.3 0.1 0.0 0.0 0.7 18.8 0.0 0.5 0.9 0.0 0.4 0.0 0.0 0.5 0.0 0.5 0.6 0.9 0.0 0.0 9.9 47.4 3.7 0.0 0.1 0.4 0.0 0.1 0.6 0.7 0.0 0.0 28.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.1 0.0 2.7 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 3.4 0.1 429.3 0.0 6.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.1 0.2 0.0 0.5 0.1 0.0 0.5 6.1 0.0 0.0 0.5 0.2 0.1 3.5 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.3 0.0 0.0 1.0 0.0 1.9 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 0.0 27.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.5 414.6 3.2 0.0 0.0 0.0 0.0 0.0 1.9 38.6 28.3 0.1 0.2 8.1 0.0 205.9 0.0 1.8 0.1 0.1 1.1 1.3 0.0 0.0 238.8 17365.8 0.1 0.0 0.0 0.0 0.0 328.3 0.0 46.1 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 1.2 0.0 0.0 0.0 2.3 9.5 0.0 0.0 0.0 0.1 17.4 0.7 0.0 0.0 0.1 17.6 0.0 0.0 0.0 FGB ENSG00000171564 "Fibrinogen beta chain" P02675 4 154563011-154572807 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Blood coagulation, Hemostasis, Immunity, Innate immunity" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 373 "liver: 17944.9" "Cell type enriched" "Detected in some" 40 "Hepatocytes: 17273.6" "Cancer enriched" "Detected in many" 42 "liver cancer: 2262.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "Hep G2: 249.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA001900, HPA001901, CAB008624" Enhanced Enhanced "Endoplasmic reticulum" "Secreted to blood" NA NA 110000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "CAB008624: AB_1615610, HPA001900: AB_1078865, HPA001901: AB_1078864" "unprognostic (1.16e-1)" "unprognostic (3.89e-2)" "unprognostic (4.65e-2)" "unprognostic (3.44e-1)" "unprognostic (2.20e-3)" "unprognostic (1.42e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (5.72e-5)" "unprognostic (2.48e-2)" "unprognostic (7.91e-2)" 2.0 0.8 0.0 0.0 0.0 0.1 2.8 0.0 0.0 1.3 0.0 0.5 0.0 0.6 0.3 0.6 0.8 0.4 1.4 0.0 0.0 48.0 17944.9 0.5 0.1 0.0 0.0 0.6 3.3 0.0 0.5 1.0 0.0 0.4 0.0 0.0 0.4 0.0 0.5 0.5 1.2 0.0 0.0 12.1 6.8 0.5 0.0 0.3 0.4 0.0 0.1 0.5 0.7 0.0 0.0 20.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.0 2.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 2.2 0.1 249.9 0.0 5.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 1.7 0.2 0.0 0.6 0.0 0.0 0.2 3.8 0.0 0.0 0.0 0.0 0.0 2.9 0.3 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.8 0.0 0.9 0.0 2.2 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 39.5 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.6 251.6 0.0 3.7 0.0 0.0 0.0 0.0 1.9 10.6 0.5 0.6 0.8 13.1 1.8 302.1 0.0 3.8 0.2 0.0 0.0 5.9 0.0 0.0 318.1 17273.6 0.3 0.0 0.0 0.0 0.0 421.7 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 24.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 23.7 0.0 0.0 0.0 FGFR3 "ACH, CD333, CEK2, JTK4" ENSG00000068078 "Fibroblast growth factor receptor 3" P22607 4 1793293-1808872 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Apoptosis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Deafness, Disease variant, Dwarfism, Ectodermal dysplasia, FDA approved drug targets, Lacrimo-auriculo-dento-digital syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 148.3;esophagus: 139.7;skin 1: 271.5" "Cell type enhanced" "Detected in many" "Astrocytes: 410.4;Basal keratinocytes: 103.8;Cholangiocytes: 91.5;Suprabasal keratinocytes: 88.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 48.2;HaCaT: 34.9;Hep G2: 80.6;NTERA-2: 36.1;RT4: 64.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004231, HPA067204" Enhanced Supported "Endoplasmic reticulum" "Secreted - unknown location" NA NA 2500000 "Cluster 27: Brain & Skin - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 64: Astrocytes - Nervous system maintenance" "Endoplasmic reticulum" "CAB004231: AB_627596, HPA067204: AB_2685804" "unprognostic (1.34e-1)" "unprognostic (5.29e-3)" "unprognostic (1.49e-1)" "prognostic unfavorable (3.77e-4)" "unprognostic (5.90e-2)" "unprognostic (1.24e-3)" "unprognostic (7.22e-2)" "unprognostic (2.54e-1)" "unprognostic (1.99e-1)" "unprognostic (2.17e-1)" "unprognostic (1.38e-1)" "unprognostic (2.88e-2)" "unprognostic (1.30e-1)" "unprognostic (9.11e-3)" "unprognostic (1.98e-1)" "unprognostic (4.74e-2)" "unprognostic (1.97e-1)" 1.6 1.6 118.0 1.5 140.6 1.4 5.5 115.6 104.0 23.7 37.4 12.2 19.5 1.5 2.8 139.7 2.2 7.9 4.8 100.8 107.6 39.3 40.7 7.4 0.4 144.7 129.2 0.5 76.4 0.2 16.1 9.3 109.8 13.8 5.2 0.2 20.2 15.0 1.3 271.5 14.7 0.4 108.9 4.0 7.8 17.6 148.3 1.7 1.5 0.9 11.1 23.1 60.9 81.2 0.0 3.8 19.5 5.6 0.0 0.3 22.1 2.4 0.3 0.8 0.4 48.2 1.0 0.0 17.8 0.7 0.7 34.9 5.5 0.3 0.3 0.2 19.3 14.2 3.9 80.6 0.1 0.0 0.6 0.0 10.9 0.2 0.1 0.1 0.1 2.3 16.7 0.1 0.0 23.9 0.8 0.5 36.1 19.5 0.1 1.2 1.0 0.3 2.8 64.1 5.7 1.6 1.9 4.0 0.0 22.2 20.4 2.5 1.0 0.0 2.1 0.5 1.6 0.1 0.0 0.0 0.2 1.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 118.0 140.6 115.6 104.0 100.8 107.6 144.7 129.2 109.8 108.9 148.3 81.2 2.2 0.0 32.5 410.4 1.1 103.8 4.1 29.8 23.9 0.0 4.8 1.5 3.1 91.5 37.6 14.7 0.0 0.5 1.6 36.1 0.0 5.0 7.9 3.0 1.7 3.4 4.2 0.0 0.5 0.7 12.0 3.2 3.6 4.0 0.0 0.1 16.1 30.4 0.6 0.0 1.3 20.7 4.1 1.2 6.5 1.3 0.6 0.6 12.4 14.0 0.6 0.1 0.0 34.2 2.2 0.4 18.0 0.4 0.0 4.2 21.2 9.9 9.8 0.6 0.0 0.7 2.9 0.4 25.9 55.0 88.7 0.8 0.7 0.1 17.0 12.8 FGG ENSG00000171557 "Fibrinogen gamma chain" P02679 4 154604134-154612967 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 330 "liver: 16556.3" "Cell type enriched" "Detected in some" 16 "Hepatocytes: 10221.7" "Cancer enriched" "Detected in many" 19 "liver cancer: 1503.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 56 "Hep G2: 735.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA027529, CAB033120, HPA074638" Supported Approved "Endoplasmic reticulum" "Secreted to blood" NA NA 267000000000 73000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "CAB033120: AB_2103818, HPA027529: AB_10601322, HPA074638: " "unprognostic (1.26e-2)" "unprognostic (4.77e-3)" "unprognostic (6.33e-3)" "unprognostic (3.69e-3)" "unprognostic (2.18e-3)" "unprognostic (9.63e-2)" "unprognostic (7.57e-3)" "prognostic unfavorable (1.00e-6)" "unprognostic (1.75e-3)" "unprognostic (3.21e-1)" "unprognostic (1.14e-1)" 1.7 34.1 0.0 0.0 0.0 0.0 1.7 0.0 0.0 1.3 0.0 0.4 0.0 0.4 0.2 0.6 0.7 25.0 1.2 0.0 0.0 8.8 16556.3 50.2 0.1 0.0 0.0 1.4 15.8 0.0 0.4 6.3 0.0 0.4 0.0 0.0 0.4 0.3 0.4 0.5 0.6 0.0 0.0 9.1 8.7 3.0 0.1 0.3 0.4 0.0 0.0 0.5 0.6 0.1 0.0 13.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 10.2 0.0 1.1 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 3.5 0.4 735.3 0.2 8.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.2 0.3 0.0 0.6 0.0 0.0 0.3 6.4 0.0 0.0 0.6 0.0 0.0 5.3 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.5 0.1 0.1 1.7 0.0 3.6 0.2 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 19.2 214.4 0.0 31.5 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.3 633.4 2.5 0.0 0.0 0.0 0.0 0.1 0.0 21.9 4.3 0.0 0.1 9.2 0.0 157.7 0.0 48.5 0.2 0.5 0.0 0.1 11.4 1.1 202.4 10221.7 0.2 0.0 0.0 0.0 0.0 289.5 0.0 0.5 0.0 0.8 0.0 0.0 2.0 0.0 0.0 0.0 0.0 161.8 0.0 0.0 0.0 0.0 0.0 1.6 1.5 0.0 0.0 0.0 0.1 2.0 0.6 0.0 0.0 0.4 17.3 0.2 0.0 0.0 FKBP7 FKBP23 ENSG00000079150 "FKBP prolyl isomerase 7" Q9Y680 2 178463664-178478600 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 50.0" "Cell type enhanced" "Detected in many" "Early spermatids: 149.1;Endometrial stromal cells: 54.8;Fibroblasts: 67.6;Leydig cells: 64.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 155.0;ASC TERT1: 96.7;fHDF/TERT166: 60.9;HSkMC: 64.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008707 Approved Supported Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA008707: AB_1848624" "unprognostic (1.33e-1)" "unprognostic (1.89e-2)" "unprognostic (1.43e-1)" "unprognostic (1.67e-1)" "unprognostic (5.61e-2)" "unprognostic (1.44e-1)" "unprognostic (1.25e-1)" "unprognostic (1.48e-1)" "unprognostic (1.34e-2)" "unprognostic (1.83e-2)" "unprognostic (6.05e-2)" "unprognostic (8.96e-3)" "prognostic unfavorable (4.61e-6)" "unprognostic (3.50e-3)" "unprognostic (1.34e-2)" "unprognostic (4.19e-3)" "unprognostic (1.10e-1)" 9.3 5.4 1.5 3.9 1.6 1.4 11.9 2.6 2.8 23.1 1.5 8.3 2.8 27.8 11.3 5.9 15.1 15.4 12.3 1.6 1.8 5.2 8.3 7.8 2.9 1.6 1.5 50.0 2.8 2.7 5.0 13.0 1.5 9.3 6.2 2.1 5.0 13.3 3.8 4.2 4.4 19.2 1.2 3.0 5.4 4.4 1.5 2.5 6.6 6.5 2.8 11.6 10.2 2.1 0.2 1.9 18.5 27.8 155.0 96.7 1.7 33.3 55.0 5.9 19.0 0.3 1.9 5.4 7.3 60.9 5.5 0.3 7.1 2.8 10.3 4.5 3.9 5.7 7.3 5.5 23.7 3.5 3.8 64.7 1.4 24.0 3.4 44.2 19.8 6.6 2.5 3.4 25.2 0.3 6.1 6.0 3.6 3.5 2.9 7.8 31.9 7.7 8.4 0.6 9.7 32.0 7.0 0.2 6.2 12.7 0.5 6.8 18.2 11.0 6.8 12.8 3.2 6.3 7.2 2.6 19.9 8.7 24.3 0.0 0.4 0.0 1.0 0.7 1.2 1.1 0.9 0.7 2.6 0.7 0.9 1.0 0.0 0.6 0.0 2.1 1.1 0.4 1.5 1.6 2.6 2.8 1.6 1.8 1.6 1.5 1.5 1.2 1.5 2.1 16.2 6.4 4.1 2.9 5.4 7.0 9.3 19.6 7.4 4.2 6.7 13.6 16.1 2.8 5.2 7.3 0.0 7.6 2.7 0.7 1.9 10.9 149.1 3.4 54.8 19.3 1.2 4.2 1.6 8.4 22.4 67.6 4.1 3.5 14.0 19.0 15.7 11.9 5.8 5.0 3.7 5.6 14.2 4.4 13.6 27.1 64.0 3.8 17.8 4.7 1.6 4.2 1.0 7.1 4.2 3.9 0.7 48.5 10.3 3.4 0.4 3.7 2.1 3.6 6.6 31.1 37.7 8.5 5.1 3.7 5.8 5.1 5.5 30.4 3.1 4.1 FLT3 "CD135, FLK2, STK1" ENSG00000122025 "Fms related receptor tyrosine kinase 3" P36888 13 28003274-28100592 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, RAS pathway related proteins" "Host-virus interaction" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.3;brain: 4.9;lymphoid tissue: 6.5" "Cell type enhanced" "Detected in some" "dendritic cells: 24.4;Inhibitory neurons: 59.9;Kupffer cells: 29.1;Langerhans cells: 21.4;Macrophages: 16.9;monocytes: 39.5" "Cancer enhanced" "Detected in some" "breast cancer: 1.8" "Region enhanced" "Detected in some" "cerebellum: 4.9" "Group enriched" "Detected in many" 13 "myeloid DC: 68.7;plasmacytoid DC: 26.2" "Lineage enriched" "Detected in many" 19 "dendritic cells: 68.7" "Group enriched" "Detected in some" 11 "REH: 42.5;THP-1: 26.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA047539 Approved "Endoplasmic reticulum" NA NA 210000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 14: REH - Unknown function" "Cluster 41: Macrophages - Immune response" "Endoplasmic reticulum" "HPA047539: AB_2680080" "unprognostic (2.19e-3)" "unprognostic (3.16e-3)" "unprognostic (6.54e-3)" "unprognostic (9.96e-2)" "unprognostic (3.88e-1)" "unprognostic (3.96e-7)" "unprognostic (7.99e-3)" "unprognostic (1.65e-2)" "unprognostic (5.37e-2)" "unprognostic (1.01e-2)" "unprognostic (1.96e-1)" "unprognostic (1.03e-1)" "unprognostic (4.56e-2)" "unprognostic (3.65e-1)" "unprognostic (3.91e-2)" "unprognostic (2.51e-1)" "unprognostic (2.22e-1)" 0.5 0.1 0.3 3.0 0.2 5.3 1.5 4.9 0.8 0.5 0.1 0.7 0.3 0.2 0.1 0.6 0.4 1.6 0.1 0.2 0.5 1.5 0.5 0.7 6.5 1.3 0.9 0.1 2.8 0.0 0.0 0.0 1.7 0.1 0.8 0.0 0.4 0.2 0.0 0.7 1.6 0.8 0.8 5.7 0.6 0.6 0.8 4.7 0.1 0.3 3.6 1.3 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.2 0.6 0.0 0.0 42.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 26.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 3.6 3.4 0.0 0.8 0.0 0.2 0.0 0.0 68.7 0.0 0.0 0.0 0.1 2.0 0.0 26.2 0.0 2.7 0.3 0.2 4.9 0.8 0.2 0.5 1.3 0.9 1.7 0.8 0.8 0.8 0.0 0.0 0.0 2.3 1.5 0.3 0.0 0.0 0.0 0.0 1.5 1.0 0.4 1.5 0.0 0.0 0.0 0.0 24.4 0.0 0.0 2.7 3.7 0.3 0.1 0.2 0.0 8.2 7.4 0.0 0.0 0.2 0.0 1.1 0.0 0.0 0.7 0.1 0.5 0.0 59.9 0.0 0.0 29.1 21.4 2.3 0.0 16.9 1.8 1.9 39.5 0.0 0.0 1.5 4.2 0.1 0.0 0.0 2.2 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.2 0.6 0.0 0.6 0.0 1.7 0.0 0.0 0.0 FNDC3B "DKFZp762K137, FAD104, FLJ23399, PRO4979, YVTM2421" ENSG00000075420 "Fibronectin type III domain containing 3B" Q53EP0 3 172039578-172401669 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 283.6" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "cerebral cortex: 29.4;hypothalamus: 8.2;pons: 9.4;thalamus: 14.4" "Immune cell enhanced" "Detected in many" "neutrophil: 37.5" "Lineage enriched" "Detected in all" 4 "granulocytes: 37.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007859 Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "HPA007859: AB_1078900" "unprognostic (7.18e-2)" "prognostic unfavorable (2.41e-5)" "unprognostic (6.03e-2)" "unprognostic (6.38e-2)" "prognostic unfavorable (6.94e-4)" "unprognostic (3.25e-2)" "prognostic unfavorable (9.85e-4)" "unprognostic (2.17e-3)" "unprognostic (1.98e-1)" "unprognostic (2.46e-2)" "prognostic unfavorable (9.06e-5)" "unprognostic (3.50e-2)" "prognostic unfavorable (5.65e-7)" "unprognostic (4.35e-2)" "unprognostic (1.19e-1)" "unprognostic (3.51e-2)" "unprognostic (3.00e-2)" 34.4 25.5 1.1 26.3 1.1 37.0 16.6 0.6 29.4 26.0 11.9 19.8 13.0 21.9 18.2 9.2 12.5 19.4 24.4 3.5 8.2 17.5 28.5 21.8 8.9 3.3 3.4 22.8 28.3 15.0 8.5 52.7 9.4 12.9 19.6 4.4 21.3 15.6 21.2 7.0 11.4 25.4 0.7 14.7 20.6 9.3 14.4 6.8 32.4 18.5 11.0 38.6 9.5 1.9 47.4 55.9 36.0 43.5 107.6 73.6 87.6 68.3 73.1 43.3 58.3 30.5 100.5 4.2 178.9 99.0 85.6 27.4 12.4 53.2 74.9 27.5 9.2 6.0 34.8 78.6 109.2 62.1 100.1 75.5 24.9 80.8 75.9 102.8 116.7 8.1 10.9 32.6 44.3 14.8 2.4 24.9 20.8 18.0 22.0 5.4 37.5 21.9 44.8 42.1 2.2 10.8 62.2 30.6 53.9 49.3 31.1 28.5 182.6 60.5 28.5 78.9 52.2 67.3 84.0 9.3 63.5 32.7 61.0 13.5 8.3 20.4 4.2 5.3 1.8 1.1 1.3 2.3 4.7 0.1 1.4 2.5 37.5 4.6 2.7 0.7 1.2 3.4 1.1 1.1 0.6 29.4 3.5 8.2 3.3 3.4 9.4 0.7 14.4 1.9 54.8 86.6 49.0 115.2 19.2 63.9 51.4 61.1 39.3 7.5 27.4 31.9 51.0 41.5 47.9 46.0 12.5 41.4 29.2 53.1 15.6 69.8 16.2 73.7 73.4 61.5 16.8 16.4 37.9 45.6 99.6 103.7 32.6 179.5 15.2 95.2 58.2 68.9 47.1 0.0 43.9 30.7 12.2 59.2 53.3 9.3 57.5 65.1 69.4 155.5 52.2 17.4 39.1 115.6 31.4 78.5 44.8 54.5 283.6 67.8 16.1 35.7 33.6 11.5 52.6 89.4 69.1 2.3 3.2 18.6 33.5 34.8 23.1 26.0 26.2 88.4 FXYD5 OIT2 ENSG00000089327 "FXYD domain containing ion transport regulator 5" Q96DB9 19 35154730-35169881 "Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 462.9;Hofbauer cells: 430.3;Langerhans cells: 492.1;Pancreatic endocrine cells: 585.0;T-cells: 459.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010817 Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Endoplasmic reticulum" "HPA010817: AB_1849214" "unprognostic (3.97e-3)" "unprognostic (5.49e-2)" "unprognostic (6.37e-3)" "unprognostic (3.01e-1)" "unprognostic (2.50e-3)" "unprognostic (4.39e-3)" "unprognostic (4.68e-2)" "unprognostic (1.56e-3)" "unprognostic (3.85e-1)" "unprognostic (5.66e-3)" "unprognostic (4.78e-2)" "unprognostic (4.75e-2)" "prognostic unfavorable (3.71e-9)" "unprognostic (6.07e-2)" "unprognostic (7.88e-2)" "unprognostic (3.61e-2)" "unprognostic (1.74e-1)" 203.1 39.2 30.8 130.8 31.0 275.2 171.1 31.9 47.2 226.2 36.9 59.0 28.6 75.5 20.1 116.1 103.6 68.8 82.3 29.9 36.6 42.0 40.2 148.5 187.4 43.4 34.7 28.6 28.0 17.2 39.8 91.7 37.9 68.8 43.3 3.5 70.3 46.5 28.6 85.8 106.6 59.8 35.4 238.3 67.9 9.2 40.0 85.0 59.2 32.6 187.8 104.8 183.8 39.9 932.2 216.7 0.2 0.9 310.5 390.2 213.6 521.7 686.4 362.8 269.3 61.9 263.6 212.9 139.3 632.2 130.3 212.3 132.5 321.3 231.4 265.7 87.9 397.7 111.8 0.5 244.3 228.6 378.0 233.6 141.6 265.3 452.2 213.2 348.5 58.0 380.0 989.0 229.5 1.5 27.4 95.1 66.4 853.4 126.0 127.6 45.0 272.7 134.0 5.2 38.8 0.3 287.1 148.6 316.6 115.0 78.0 180.4 494.8 443.6 170.0 487.7 40.2 1.5 16.2 54.4 675.9 524.8 694.4 644.0 596.4 111.1 451.5 628.4 422.0 602.8 756.5 467.4 718.7 545.6 489.2 405.6 140.1 840.8 636.9 325.0 894.6 934.1 30.8 31.0 31.9 47.2 29.9 36.6 43.4 34.7 37.9 35.4 40.0 39.9 291.0 3.2 13.4 0.0 330.7 107.1 73.4 106.3 54.1 0.6 80.2 51.2 5.2 32.9 27.8 99.3 0.0 18.9 349.7 2.9 0.0 156.1 1.7 3.4 63.5 276.5 10.7 111.2 2.2 197.3 462.9 93.1 71.9 2.2 361.5 0.3 323.8 6.1 430.3 0.0 0.4 8.2 4.1 385.9 492.1 4.6 6.5 403.9 209.9 10.3 243.7 0.4 260.6 1.0 0.1 585.0 7.8 0.7 302.5 72.2 0.2 4.4 5.5 0.4 65.7 5.7 107.6 1.6 8.1 24.0 69.2 50.9 459.5 0.7 10.0 100.3 FZD8 ENSG00000177283 "Frizzled class receptor 8" Q9H461 10 35638247-35642296 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 39.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 19.2;Gastric mucus-secreting cells: 13.7;Muller glia cells: 27.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 15.6;PC-3: 40.3;U-138 MG: 14.8;U-251 MG: 13.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA045025, HPA071142" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 5: Muller glia cells - Visual perception" "Endoplasmic reticulum" "HPA045025: AB_10795888, HPA071142: AB_2686349" "unprognostic (1.20e-1)" "unprognostic (4.42e-3)" "unprognostic (1.85e-2)" "unprognostic (1.97e-1)" "unprognostic (2.21e-2)" "unprognostic (2.94e-1)" "unprognostic (1.61e-1)" "unprognostic (1.08e-3)" "unprognostic (1.11e-1)" "unprognostic (1.53e-1)" "prognostic favorable (8.21e-4)" "unprognostic (4.92e-2)" "unprognostic (2.25e-1)" "unprognostic (4.85e-2)" "unprognostic (1.68e-1)" "unprognostic (7.34e-3)" "unprognostic (1.19e-1)" 5.6 1.4 5.2 1.2 5.8 0.1 3.7 1.8 6.1 2.3 39.4 8.7 0.6 2.5 0.5 0.9 5.4 1.3 9.7 5.9 2.1 6.9 3.1 4.4 1.3 1.8 3.3 1.8 4.7 2.4 2.7 0.4 2.0 1.3 2.0 3.9 3.3 1.4 3.1 3.7 2.0 1.6 1.5 11.7 7.2 2.5 4.3 1.4 6.7 2.5 0.6 1.8 1.6 5.0 0.0 4.4 0.7 0.0 1.7 0.1 2.6 4.8 0.2 0.2 0.2 0.5 0.7 0.0 0.7 2.1 4.8 1.5 0.5 1.5 0.0 0.0 12.4 0.0 0.5 0.2 0.8 0.0 0.3 1.5 6.0 9.7 3.8 15.6 3.4 0.0 0.3 0.0 1.3 1.9 0.0 0.0 4.0 0.3 40.3 4.1 2.5 0.0 7.7 0.3 12.0 0.4 0.9 0.2 0.0 5.5 0.1 0.7 8.1 14.8 2.2 7.3 13.4 0.0 0.0 0.0 8.5 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 5.8 1.8 6.1 5.9 2.1 1.8 3.3 2.0 1.5 4.3 5.0 12.2 19.2 3.3 12.4 0.0 0.3 1.0 4.2 2.2 0.6 4.1 10.8 10.2 1.5 3.1 0.0 2.1 0.1 0.5 11.2 0.0 3.4 0.0 4.2 2.7 7.2 1.2 0.0 0.4 3.1 0.3 6.1 13.7 9.3 0.0 1.6 10.4 4.5 0.6 0.0 0.5 2.7 0.0 0.8 1.3 0.1 1.2 1.2 0.0 1.9 0.2 27.2 0.0 1.0 0.3 3.5 1.5 2.2 0.1 0.8 0.5 4.2 2.1 1.3 6.6 2.7 5.8 0.2 1.4 1.2 1.1 0.1 0.4 0.7 4.8 0.2 G6PC3 UGRP ENSG00000141349 "Glucose-6-phosphatase catalytic subunit 3" Q9BUM1 17 44070735-44076344 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Gluconeogenesis Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067052 Supported "Endoplasmic reticulum" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 47: Cytotrophoblasts - Unknown function" "Endoplasmic reticulum" "HPA067052: AB_2685771" "unprognostic (9.13e-2)" "unprognostic (2.28e-1)" "unprognostic (3.61e-1)" "prognostic favorable (1.11e-4)" "unprognostic (1.88e-3)" "unprognostic (3.16e-1)" "prognostic unfavorable (9.61e-4)" "unprognostic (2.79e-1)" "unprognostic (2.43e-1)" "unprognostic (1.15e-2)" "unprognostic (2.59e-2)" "unprognostic (1.85e-3)" "unprognostic (1.87e-3)" "unprognostic (4.53e-2)" "unprognostic (3.06e-2)" "unprognostic (2.35e-1)" "unprognostic (4.49e-2)" 56.7 97.2 64.8 22.5 67.8 16.0 55.6 70.5 79.3 47.6 88.8 42.1 28.7 55.4 63.9 37.1 45.6 23.9 61.9 65.3 77.5 75.2 26.4 42.9 19.3 74.9 86.9 44.3 56.5 66.7 95.1 25.8 96.1 59.5 18.2 17.1 48.7 40.6 54.3 26.8 39.6 23.0 67.9 45.2 51.4 55.1 72.7 15.2 71.1 26.4 12.0 48.7 37.7 72.4 40.0 231.7 73.7 128.5 77.9 58.3 55.3 45.0 86.9 96.2 64.4 97.1 62.3 88.9 62.8 95.1 65.4 67.4 53.5 92.1 44.5 46.4 86.0 49.3 142.5 182.4 84.1 46.1 59.8 77.3 44.3 93.1 62.3 59.6 79.3 35.9 51.5 109.6 72.5 112.1 22.4 71.4 99.3 48.7 133.5 45.6 48.4 207.5 137.6 93.6 92.7 83.0 49.1 57.4 59.3 82.9 158.6 45.1 87.6 98.8 53.1 26.8 63.5 74.0 56.2 26.1 110.3 38.2 128.9 3.0 33.1 7.9 9.9 43.4 12.1 12.1 8.0 9.1 54.2 13.9 9.7 12.9 1.4 17.5 26.3 74.5 8.5 16.9 64.8 67.8 70.5 79.3 65.3 77.5 74.9 86.9 96.1 67.9 72.7 72.4 22.3 3.2 12.9 5.2 10.4 2.5 17.3 31.8 8.0 10.5 20.7 21.5 6.4 21.5 25.2 40.5 12.5 64.3 17.1 12.4 13.7 59.3 5.0 18.9 22.1 26.0 22.9 9.7 2.8 49.4 41.1 25.0 16.8 20.1 18.3 20.2 18.5 7.1 58.7 5.0 4.5 14.1 24.4 21.6 12.2 6.2 20.2 20.9 14.2 0.0 21.8 30.7 10.3 8.0 5.5 33.6 13.6 23.0 27.2 19.5 20.5 36.0 24.6 8.3 13.1 15.3 21.4 31.5 26.7 14.3 2.6 42.5 7.0 43.9 19.7 17.2 GANAB "G2AN, GIIA, GluII, KIAA0088" ENSG00000089597 "Glucosidase II alpha subunit" Q14697 11 62624826-62646726 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026874, HPA061426" Enhanced Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA 23000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "HPA026874: AB_1849745, HPA061426: AB_2684516" "unprognostic (2.12e-1)" "unprognostic (5.95e-3)" "unprognostic (4.35e-2)" "unprognostic (2.12e-1)" "unprognostic (1.20e-2)" "unprognostic (3.65e-2)" "prognostic unfavorable (1.27e-5)" "unprognostic (5.80e-3)" "unprognostic (1.09e-1)" "unprognostic (1.79e-1)" "unprognostic (1.68e-3)" "unprognostic (5.91e-2)" "unprognostic (1.01e-3)" "unprognostic (3.81e-2)" "unprognostic (1.82e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (9.54e-4)" 93.9 73.7 31.8 88.2 34.5 83.7 92.8 36.6 36.7 112.6 51.6 104.7 95.6 102.1 151.7 66.4 106.9 75.3 67.9 31.7 41.2 98.5 171.7 86.8 81.7 38.5 34.9 115.5 88.1 130.6 21.8 141.8 38.1 97.5 116.8 79.4 101.8 111.1 39.4 74.7 90.5 126.0 36.5 86.7 85.2 66.1 39.8 105.2 132.6 53.0 94.8 90.7 34.2 43.4 298.2 245.9 318.2 552.0 464.1 389.0 332.9 312.4 480.4 436.2 362.1 222.2 515.9 201.2 616.0 572.5 337.8 376.4 375.2 376.7 443.8 155.8 191.3 202.9 317.8 125.6 389.0 325.7 248.7 397.2 248.4 433.6 475.3 533.0 422.3 199.6 278.5 352.9 398.2 313.6 167.6 193.4 262.3 236.6 237.7 209.5 368.7 513.1 285.7 230.3 168.6 221.2 451.1 308.2 370.8 321.6 380.9 304.8 311.6 430.0 272.2 342.9 309.9 360.8 423.8 152.2 473.9 173.1 421.7 23.9 19.3 19.1 23.8 23.4 23.1 15.9 17.2 20.0 20.8 14.9 20.9 21.3 8.9 29.8 22.2 18.4 17.3 22.6 31.8 34.5 36.6 36.7 31.7 41.2 38.5 34.9 38.1 36.5 39.8 43.4 42.7 12.8 20.7 17.3 29.8 28.3 29.4 45.8 13.6 31.4 57.4 53.8 7.8 52.9 24.2 68.0 60.5 81.7 33.4 40.1 5.9 47.0 18.5 31.4 59.1 42.2 31.8 25.0 12.6 42.6 137.3 45.9 27.5 46.5 11.4 72.8 48.2 98.0 57.9 35.3 16.0 48.9 34.6 45.8 25.1 16.4 58.4 32.7 35.6 15.9 38.9 36.5 38.1 11.1 16.5 39.5 29.3 68.1 50.4 34.0 47.8 27.0 26.3 41.4 32.9 36.4 34.7 25.3 47.4 21.2 31.3 80.2 25.2 63.1 56.3 32.4 GDAP1L1 ENSG00000124194 "Ganglioside induced differentiation associated protein 1 like 1" Q96MZ0 20 44247099-44280947 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 30.7;pituitary gland: 17.7" "Cell type enhanced" "Detected in some" "Bipolar cells: 8.4;Early spermatids: 9.8;Excitatory neurons: 20.9;Horizontal cells: 15.2;Inhibitory neurons: 23.4;Late spermatids: 30.4;Oligodendrocyte precursor cells: 10.1" "Cancer enriched" "Detected in single" 14 "glioma: 6.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "NTERA-2: 12.5;SCLC-21H: 32.3;SH-SY5Y: 14.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054182, HPA063265" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" "Endoplasmic reticulum" "HPA054182: , HPA063265: AB_2684972" "unprognostic (6.58e-3)" "unprognostic (2.58e-1)" "unprognostic (2.30e-1)" "unprognostic (2.23e-4)" "unprognostic (3.69e-1)" "unprognostic (5.15e-1)" "unprognostic (6.45e-2)" "unprognostic (7.69e-2)" "unprognostic (1.53e-1)" "unprognostic (5.07e-1)" "unprognostic (4.74e-3)" "unprognostic (2.41e-1)" "unprognostic (3.81e-5)" "unprognostic (8.57e-2)" "unprognostic (1.87e-1)" "unprognostic (3.21e-2)" "unprognostic (1.13e-1)" 0.1 2.2 21.6 0.2 27.0 0.1 0.1 14.2 30.7 1.1 0.1 0.6 0.0 0.6 0.0 0.0 0.2 0.0 1.6 26.6 15.4 0.1 0.1 0.0 0.0 17.0 10.5 2.7 0.5 0.9 17.7 0.0 15.8 0.2 0.0 5.7 0.0 0.0 0.0 0.3 0.3 0.1 6.2 0.0 0.7 3.5 14.0 0.0 0.2 0.0 0.0 0.1 0.3 21.2 0.0 0.0 3.8 0.1 0.0 0.0 0.2 0.0 0.0 0.3 0.2 0.0 0.0 0.2 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.4 0.1 0.2 0.8 0.1 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.0 0.1 0.1 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.3 14.8 0.0 0.1 1.5 0.2 0.0 3.9 0.1 1.1 0.7 0.3 0.0 0.0 0.2 0.8 1.1 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.6 27.0 14.2 30.7 26.6 15.4 17.0 10.5 15.8 6.2 14.0 21.2 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 9.8 0.0 0.1 0.2 0.0 0.0 20.9 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 15.2 23.4 0.4 0.0 0.0 0.0 30.4 0.6 0.0 0.0 6.5 0.0 1.1 0.0 10.1 3.3 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 2.2 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 GDAP2 "dJ776P7.1, FLJ20142, MACROD3" ENSG00000196505 "Ganglioside induced differentiation associated protein 2" Q9NXN4 1 117863485-117929621 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046185 Approved Approved "Endoplasmic reticulum" Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 59: Non-specific - Transcription" "Endoplasmic reticulum" "HPA046185: AB_10960897" "unprognostic (4.12e-2)" "unprognostic (1.40e-1)" "unprognostic (2.64e-1)" "unprognostic (1.82e-2)" "unprognostic (4.33e-2)" "unprognostic (1.05e-1)" "unprognostic (1.53e-3)" "unprognostic (1.25e-1)" "unprognostic (2.60e-1)" "unprognostic (4.26e-3)" "unprognostic (2.26e-3)" "unprognostic (6.38e-2)" "unprognostic (1.18e-1)" "unprognostic (4.09e-2)" "unprognostic (3.28e-2)" "unprognostic (8.68e-2)" "unprognostic (1.68e-1)" 3.0 2.4 2.3 3.2 2.1 8.0 3.2 3.6 2.7 3.4 3.4 3.8 4.0 2.8 4.0 3.1 2.4 3.2 2.5 2.0 2.3 4.8 5.1 3.4 3.6 2.1 2.6 2.4 4.5 4.9 2.3 4.1 2.4 3.4 4.4 2.9 3.0 3.3 1.8 2.9 4.7 3.0 2.4 4.2 4.4 4.8 2.7 4.1 4.6 2.1 4.4 4.5 3.1 2.9 9.2 5.1 6.1 5.1 6.5 3.1 9.0 5.2 6.8 10.3 9.9 5.4 6.2 3.6 6.2 7.1 7.8 5.3 8.1 6.8 12.6 7.2 4.7 5.4 6.7 5.9 7.7 6.8 6.6 2.5 8.5 12.9 9.9 4.7 6.9 8.1 5.7 7.6 8.6 9.6 6.0 5.5 10.6 6.9 8.8 3.2 16.7 5.3 5.8 9.1 4.6 5.1 6.3 10.7 8.2 18.3 3.7 6.8 4.3 7.3 8.5 8.5 7.1 7.9 6.1 5.1 9.4 4.8 9.1 11.4 6.7 12.6 2.4 7.2 3.8 2.3 2.7 2.9 6.5 2.2 2.4 2.3 6.5 4.1 7.6 1.5 3.6 3.2 2.3 2.1 3.6 2.7 2.0 2.3 2.1 2.6 2.4 2.4 2.7 2.9 9.2 9.6 8.6 27.7 13.5 13.5 6.5 8.1 8.6 13.1 8.1 5.5 7.8 8.6 10.8 3.7 18.8 12.4 11.6 13.4 7.9 10.6 21.2 12.8 9.0 7.6 4.2 13.9 36.7 6.2 11.4 7.7 18.3 11.5 0.0 10.4 6.4 9.0 13.8 15.2 39.1 14.0 14.2 17.2 15.8 5.7 5.9 20.0 10.6 34.7 16.2 9.2 8.2 31.7 35.8 10.7 7.5 7.2 21.0 9.8 17.8 10.2 10.5 13.7 0.0 8.6 10.2 28.4 14.5 14.3 13.8 21.1 13.8 6.7 8.3 9.6 GGNBP2 "DIF-3, DIF3, FLJ21230, FLJ22561, LZK1, ZFP403, ZNF403" ENSG00000278311 "Gametogenetin binding protein 2" Q9H3C7 17 36544912-36589848 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 467.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018914, HPA073392" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" "Endoplasmic reticulum" "HPA018914: AB_2294667, HPA073392: AB_2686599" "unprognostic (2.68e-1)" "unprognostic (5.19e-2)" "unprognostic (2.35e-2)" "unprognostic (1.03e-1)" "unprognostic (3.41e-1)" "unprognostic (6.12e-2)" "unprognostic (1.88e-3)" "unprognostic (2.83e-1)" "unprognostic (7.29e-2)" "unprognostic (3.29e-2)" "unprognostic (3.82e-1)" "unprognostic (1.07e-1)" "unprognostic (4.28e-2)" "unprognostic (3.75e-1)" "unprognostic (1.47e-1)" "unprognostic (1.50e-2)" "unprognostic (1.95e-2)" 41.7 30.5 23.8 29.5 23.9 79.9 35.3 26.4 30.0 32.5 24.6 38.9 33.8 34.0 26.6 33.9 34.7 25.2 31.0 24.1 25.5 31.2 36.6 33.5 49.7 25.1 25.7 40.0 35.3 31.5 26.7 27.1 25.9 27.8 30.7 26.8 33.2 23.9 52.7 40.5 44.0 27.5 23.6 39.4 34.8 60.2 24.6 36.6 29.4 32.2 46.5 37.2 34.7 26.1 48.0 49.4 45.8 38.9 53.5 63.9 33.0 60.0 48.1 44.4 44.2 48.6 34.5 64.5 37.2 47.7 44.4 46.9 37.2 55.6 58.1 38.9 36.1 36.2 55.1 43.7 55.1 63.1 47.1 62.3 68.4 45.2 61.4 56.6 38.9 46.2 51.2 62.0 62.5 29.5 65.6 51.2 13.9 31.0 26.1 44.3 60.9 42.8 58.6 93.2 37.1 32.3 58.1 33.5 97.1 46.2 63.0 64.2 39.9 62.4 43.0 41.5 62.4 42.2 50.0 48.7 40.9 34.6 38.6 42.8 31.6 67.8 37.1 35.9 43.6 56.6 46.9 41.5 42.0 48.5 66.0 62.0 44.9 40.4 39.9 84.1 50.1 20.8 23.8 23.9 26.4 30.0 24.1 25.5 25.1 25.7 25.9 23.6 24.6 26.1 85.0 67.3 84.2 38.5 110.2 96.0 98.9 128.8 111.5 70.2 58.9 46.9 81.1 60.1 118.6 31.3 37.5 82.4 132.3 94.7 52.8 74.0 467.4 87.3 84.2 82.2 57.4 71.1 46.9 68.5 77.4 86.6 56.1 104.3 97.5 52.2 65.0 64.7 73.5 57.2 43.3 79.6 101.7 77.9 66.7 130.6 79.6 84.7 58.7 33.7 103.0 71.8 94.7 29.1 48.6 73.2 74.2 72.2 84.4 83.9 124.9 63.6 107.0 71.5 59.2 99.0 114.9 335.2 98.7 91.9 96.5 95.6 117.8 53.5 97.4 102.4 GIMAP1 "HIMAP1, IAN2, IMAP1, IMAP38" ENSG00000213203 "GTPase, IMAP family member 1" Q8WWP7 7 150716606-150724284 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 24.7" "Cell type enhanced" "Detected in many" "Adipocytes: 189.8;Endothelial cells: 109.9;Hepatic stellate cells: 117.8;Kupffer cells: 109.1;monocytes: 74.9;NK-cells: 185.3;T-cells: 97.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "HUVEC TERT2: 14.7;MOLT-4: 9.2;TIME: 3.9" "Low region specificity" "Detected in many" "HPA044887, HPA053441" Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "Endoplasmic reticulum" "HPA044887: AB_10960351, HPA053441: AB_2682152" "unprognostic (1.60e-2)" "unprognostic (6.58e-3)" "unprognostic (8.21e-3)" "unprognostic (2.54e-3)" "unprognostic (1.10e-1)" "unprognostic (2.33e-3)" "prognostic favorable (1.09e-4)" "unprognostic (1.66e-2)" "unprognostic (3.54e-2)" "unprognostic (3.44e-1)" "unprognostic (4.60e-3)" "unprognostic (7.89e-2)" "unprognostic (1.77e-3)" "unprognostic (2.18e-1)" "prognostic unfavorable (6.12e-4)" "unprognostic (7.49e-2)" "unprognostic (1.96e-1)" 9.8 2.5 3.0 11.0 3.0 1.0 7.9 2.9 3.5 3.8 3.0 3.7 3.5 4.6 1.1 2.1 4.4 3.2 9.3 2.8 2.9 3.5 2.4 8.9 19.6 3.5 3.2 1.5 1.4 1.5 1.1 7.1 3.4 2.3 2.2 0.1 2.5 2.0 5.4 2.5 6.9 3.8 3.5 24.7 3.3 0.8 3.6 6.6 5.3 7.1 8.4 3.5 3.0 3.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 14.7 1.9 0.0 0.0 0.0 0.0 9.2 0.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 3.0 32.2 0.1 43.8 29.6 51.1 0.3 47.5 54.2 13.5 0.6 68.2 56.2 2.7 42.6 30.6 0.8 34.0 35.0 3.0 3.0 2.9 3.5 2.8 2.9 3.5 3.2 3.4 3.5 3.6 3.2 189.8 3.2 1.5 0.0 5.1 5.5 0.6 0.0 1.2 0.6 1.9 3.6 5.9 2.8 0.6 0.0 0.0 0.3 51.5 0.1 0.0 0.3 0.3 0.4 0.6 109.9 0.0 10.5 0.0 0.4 0.3 3.7 1.5 0.2 8.2 0.2 117.8 2.0 37.9 0.0 0.0 0.0 0.0 109.1 7.6 1.3 1.5 48.0 8.8 0.0 74.9 0.3 185.3 0.0 0.0 0.1 0.1 0.0 7.6 0.7 0.2 0.5 0.0 1.0 0.0 2.5 3.5 0.3 0.5 0.7 3.1 0.4 97.3 1.0 0.0 0.7 GIMAP1-GIMAP5 ENSG00000281887 "GIMAP1-GIMAP5 readthrough" 7 150716668-150743646 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 16.4" "Cell type enhanced" "Detected in some" "Endothelial cells: 1.3;Microglial cells: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "monocytes: 37.9;NK-cells: 69.5;T-cells: 101.0" "Group enriched" "Detected in some" 6 "HUVEC TERT2: 5.6;JURKAT: 2.3;MOLT-4: 4.5;THP-1: 1.9;TIME: 2.1" HPA053441 Supported "Endoplasmic reticulum" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 11: Alveolar cells - Smell perception" "Endoplasmic reticulum" "HPA053441: AB_2682152" 7.2 1.4 1.6 5.5 1.6 0.5 5.8 1.6 2.5 3.9 1.9 2.9 3.1 4.0 0.0 1.9 5.1 0.4 5.5 1.4 1.8 3.2 1.4 7.5 5.0 2.4 1.7 1.2 0.7 0.1 1.5 1.1 2.0 2.2 0.0 0.0 1.7 0.2 2.5 2.1 4.2 0.5 2.1 16.4 1.8 0.4 2.1 1.3 4.7 1.8 0.0 3.7 2.9 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 2.3 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.5 37.9 0.0 67.2 32.4 75.1 0.6 73.4 94.4 15.2 0.7 101.0 85.1 4.4 69.5 28.2 1.1 51.5 76.2 1.6 1.6 1.6 2.5 1.4 1.8 2.4 1.7 2.0 2.1 2.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 GPANK1 "ANKRD59, BAT4, D6S54E, G5, GPATCH10" ENSG00000204438 "G-patch domain and ankyrin repeats 1" O95872 6 31661228-31666283 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 180.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006301 Approved Approved "Endoplasmic reticulum" NA Yes "Cluster 2: Granulocytes - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Endoplasmic reticulum" "HPA006301: AB_1078267" "unprognostic (2.03e-1)" "unprognostic (2.84e-2)" "unprognostic (1.56e-1)" "unprognostic (1.05e-1)" "unprognostic (4.26e-2)" "unprognostic (1.20e-1)" "unprognostic (1.77e-2)" "unprognostic (5.72e-2)" "unprognostic (1.10e-1)" "unprognostic (8.81e-2)" "prognostic favorable (5.89e-4)" "unprognostic (2.29e-1)" "unprognostic (2.46e-2)" "unprognostic (2.00e-1)" "unprognostic (1.86e-1)" "unprognostic (5.40e-2)" "unprognostic (1.51e-1)" 14.5 11.8 1.5 2.7 1.9 3.9 14.7 3.6 2.8 14.9 1.4 15.9 1.6 15.9 2.5 11.4 14.9 2.1 21.5 1.5 1.8 14.7 16.0 13.2 3.8 2.0 1.7 17.3 15.1 3.3 13.5 1.8 2.2 14.0 2.4 2.3 13.8 2.0 28.4 15.8 15.6 1.1 1.4 16.7 15.4 36.4 1.8 6.7 12.8 2.8 2.3 15.0 13.3 2.6 3.3 3.3 1.7 5.6 8.3 6.6 4.4 3.2 5.2 3.1 4.2 0.2 4.8 10.8 5.2 3.4 4.2 3.9 0.0 8.1 2.3 6.4 5.6 11.3 0.0 3.7 5.7 3.7 4.3 3.2 4.3 10.4 6.9 6.1 3.8 10.9 3.0 8.8 4.2 2.6 13.1 4.4 0.0 5.1 1.2 5.4 7.5 7.9 5.1 2.6 12.6 8.4 4.3 1.9 5.4 4.6 5.1 9.2 4.8 7.3 7.0 0.5 0.0 6.5 10.8 4.1 8.6 7.9 4.2 11.8 3.1 9.9 4.1 2.5 4.1 2.0 3.2 2.5 3.1 2.9 3.7 3.3 9.5 4.5 2.6 3.8 4.6 2.7 1.5 1.9 3.6 2.8 1.5 1.8 2.0 1.7 2.2 1.4 1.8 2.6 22.6 38.5 21.7 5.9 30.5 25.0 24.2 27.6 23.3 29.1 25.0 23.4 35.9 30.0 21.6 18.4 35.5 30.1 28.3 26.4 45.0 31.6 55.4 21.9 21.4 29.1 27.1 33.0 3.2 23.6 39.7 23.8 13.3 22.9 35.4 21.9 27.8 30.3 27.7 11.8 3.5 29.9 22.4 27.0 18.5 51.5 34.5 21.0 19.6 3.7 43.5 37.8 47.4 5.0 7.3 21.9 43.3 24.8 29.2 32.3 90.5 74.5 20.1 47.3 19.7 21.6 29.7 180.8 87.2 16.2 34.2 47.1 26.9 17.3 26.9 19.9 GPR89A UNQ192 ENSG00000117262 "G protein-coupled receptor 89A" B7ZAQ6 1 145607988-145670650 "Predicted membrane proteins" "Ion transport, Protein transport, Transport" "Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA076096 Approved "Endoplasmic reticulum" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Endoplasmic reticulum" "HPA076096: AB_2686777" "unprognostic (1.19e-1)" "unprognostic (6.71e-2)" "unprognostic (2.44e-1)" "unprognostic (1.29e-1)" "unprognostic (3.51e-3)" "unprognostic (4.51e-2)" "unprognostic (1.99e-3)" "unprognostic (8.14e-2)" "unprognostic (4.61e-3)" "unprognostic (5.41e-2)" "unprognostic (1.96e-1)" "unprognostic (3.00e-2)" "unprognostic (1.02e-5)" "unprognostic (1.42e-1)" "unprognostic (3.70e-2)" "unprognostic (5.47e-2)" "unprognostic (1.21e-1)" 5.9 6.7 6.0 3.7 6.0 4.1 14.1 8.6 7.0 11.9 6.2 8.7 9.8 6.4 6.9 5.9 7.6 8.2 7.0 6.3 7.3 31.2 24.7 5.7 5.7 7.3 7.5 4.2 12.9 11.7 3.4 7.1 8.4 9.5 11.8 4.3 6.9 7.2 6.7 4.7 11.6 9.7 6.5 3.3 8.5 14.8 6.9 8.1 10.6 8.7 8.0 8.3 2.3 6.9 20.7 11.6 18.0 9.7 35.1 34.3 19.2 23.0 25.8 29.3 33.2 27.6 24.4 13.4 13.2 26.0 14.3 20.2 19.9 22.4 25.8 21.5 15.5 9.8 15.8 14.2 29.3 30.5 6.7 36.4 26.5 21.9 28.6 12.7 21.9 16.2 23.7 30.2 40.6 29.7 13.1 11.5 23.5 36.3 25.4 15.5 21.0 48.7 24.8 12.6 7.0 15.4 30.7 36.8 16.6 30.1 32.4 20.0 9.6 27.1 6.5 24.0 23.2 15.2 33.2 17.4 20.6 16.4 20.2 3.7 5.8 7.1 9.2 5.7 9.5 6.0 7.1 9.9 8.1 3.0 7.3 6.5 1.1 9.3 7.6 6.5 8.2 5.0 6.0 6.0 8.6 7.0 6.3 7.3 7.3 7.5 8.4 6.5 6.9 6.9 6.1 22.4 5.9 16.0 13.7 7.6 10.1 17.7 15.4 6.9 10.2 6.3 13.9 14.3 13.2 14.7 12.5 20.1 12.1 6.5 0.0 13.6 13.6 4.8 6.0 6.5 13.7 24.4 29.0 20.2 21.2 9.1 12.8 5.6 5.7 5.1 7.9 9.2 9.3 3.3 24.3 11.2 20.3 5.1 4.0 8.6 9.6 7.3 10.6 7.5 9.0 7.5 17.5 14.1 19.7 17.1 6.0 7.2 20.9 8.5 24.3 13.7 8.0 6.9 13.1 7.3 8.2 45.4 24.6 10.1 8.5 16.1 14.6 6.3 10.9 5.7 GPR89B "GPR89, GPR89C, SH120" ENSG00000188092 "G protein-coupled receptor 89B" P0CG08 1 147928393-147993592 "Predicted membrane proteins" "Ion transport, Protein transport, Transport" "Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA076096 Approved "Endoplasmic reticulum" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "Endoplasmic reticulum" "HPA076096: AB_2686777" "unprognostic (7.78e-2)" "unprognostic (1.13e-1)" "unprognostic (2.58e-2)" "unprognostic (1.37e-1)" "unprognostic (2.39e-2)" "unprognostic (1.15e-1)" "unprognostic (4.19e-3)" "unprognostic (1.05e-2)" "unprognostic (2.71e-2)" "unprognostic (1.32e-4)" "unprognostic (1.23e-2)" "unprognostic (2.38e-2)" "unprognostic (1.61e-1)" "unprognostic (2.56e-1)" "unprognostic (1.67e-1)" "unprognostic (1.69e-1)" "unprognostic (7.15e-4)" 6.1 7.1 5.3 0.2 5.0 3.1 6.4 7.7 8.2 7.7 5.6 5.4 1.7 6.8 2.5 5.7 6.2 1.8 5.6 5.2 5.4 12.5 7.2 5.4 1.4 7.9 6.6 6.6 4.4 3.1 4.8 2.1 8.6 6.2 2.2 2.0 7.3 2.5 8.8 8.5 7.0 1.1 5.5 5.0 6.4 10.5 5.8 2.6 4.8 6.0 1.3 6.3 6.2 7.2 5.8 0.3 3.5 3.8 5.9 4.1 6.5 4.4 1.8 6.3 9.1 7.7 4.3 4.8 5.1 5.7 4.8 5.4 7.7 0.8 5.3 5.9 6.8 6.6 2.1 4.1 6.3 0.4 3.0 2.0 9.0 5.6 10.4 2.2 3.4 8.2 2.7 8.5 3.5 12.3 9.8 4.4 5.9 6.4 4.4 3.9 9.8 6.8 6.4 5.8 3.0 2.8 9.0 2.2 5.0 5.2 7.2 4.0 1.8 2.5 1.4 2.6 6.5 17.6 11.2 8.0 5.6 4.1 2.8 3.5 2.5 2.4 2.3 1.9 3.3 2.2 3.2 2.4 1.8 3.0 3.1 2.7 1.3 4.4 1.5 2.0 2.6 2.1 5.3 5.0 7.7 8.2 5.2 5.4 7.9 6.6 8.6 5.5 5.8 7.2 4.4 6.4 5.3 11.1 16.3 0.1 8.2 0.1 24.5 3.0 6.2 4.7 6.6 5.7 3.8 5.5 2.1 13.4 8.8 6.0 0.0 7.2 8.1 2.8 3.0 4.1 4.8 6.7 32.2 7.1 14.1 6.3 16.3 3.2 7.0 4.4 3.3 6.7 4.2 0.0 32.4 7.2 0.0 2.2 0.3 3.7 5.6 3.7 0.0 11.2 4.1 2.4 6.2 19.1 27.8 6.8 7.8 3.4 30.0 4.3 20.4 21.9 3.6 4.0 0.0 3.5 4.0 31.1 10.6 16.1 0.0 15.7 16.1 4.7 5.9 3.6 HACD3 "B-ind1, HSPC121, PTPLAD1" ENSG00000074696 "3-hydroxyacyl-CoA dehydratase 3" Q9P035 15 65530418-65578349 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014837, HPA060347" Enhanced Enhanced "Endoplasmic reticulum" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Endoplasmic reticulum" "HPA014837: AB_1855914, HPA060347: AB_2684260" "unprognostic (1.51e-2)" "unprognostic (2.89e-1)" "unprognostic (2.29e-1)" "unprognostic (2.18e-1)" "unprognostic (3.52e-1)" "unprognostic (1.92e-2)" "unprognostic (1.67e-1)" "unprognostic (2.28e-1)" "unprognostic (3.36e-2)" "unprognostic (1.09e-1)" "unprognostic (1.73e-1)" "unprognostic (2.57e-1)" "prognostic favorable (3.09e-5)" "unprognostic (3.44e-2)" "unprognostic (5.33e-2)" "unprognostic (1.10e-2)" "unprognostic (2.04e-2)" 23.1 84.1 56.1 18.5 57.1 17.3 74.4 64.6 67.5 40.2 73.2 30.0 28.9 29.9 43.0 19.2 32.4 34.1 11.8 54.3 87.8 79.6 119.1 30.3 18.8 68.3 79.6 47.8 29.8 61.5 44.2 37.2 87.2 41.6 34.3 54.0 28.6 34.3 6.9 27.7 29.2 28.1 70.0 21.2 68.7 34.6 88.3 29.0 70.8 7.8 20.3 43.0 17.8 75.8 88.9 194.4 211.3 106.2 130.3 78.0 99.8 95.9 82.4 106.6 119.6 149.9 129.1 110.8 81.8 104.7 132.6 237.9 344.4 80.1 94.8 61.9 191.8 88.1 88.7 165.3 65.9 110.6 64.9 80.3 58.7 73.3 52.5 102.7 105.5 65.1 117.5 40.8 174.3 105.6 82.5 86.0 180.6 235.3 65.4 91.8 178.9 125.0 152.1 151.2 126.8 111.9 103.6 114.9 110.5 197.5 117.1 57.9 84.2 134.4 117.6 66.9 134.9 79.1 251.2 154.5 89.7 105.8 82.6 8.5 7.5 2.5 31.7 11.2 36.1 23.7 28.6 30.2 13.2 22.2 33.0 32.9 1.0 23.2 12.7 17.4 24.6 22.7 56.1 57.1 64.6 67.5 54.3 87.8 68.3 79.6 87.2 70.0 88.3 75.8 63.6 64.1 64.8 84.5 18.7 0.0 60.5 0.0 76.2 121.3 94.8 64.5 9.9 62.9 27.9 176.6 100.1 189.1 23.8 6.1 25.4 71.3 107.2 62.8 76.2 51.8 43.7 67.3 57.5 46.3 124.4 62.7 73.4 39.8 16.4 127.0 42.1 165.2 51.2 139.7 97.1 26.3 0.0 23.1 0.0 32.5 87.3 22.2 0.0 29.0 5.2 89.8 16.5 57.8 66.7 32.1 18.2 88.4 28.9 71.5 28.3 56.2 36.5 83.7 78.9 40.9 41.9 156.9 110.3 54.3 0.0 113.1 22.3 136.2 45.1 78.7 HM13 "dJ324O17.1, H13, IMP1, IMPAS, PSENL3, PSL3, SPP, SPPL1" ENSG00000101294 "Histocompatibility minor 13" Q8TCT9 20 31514410-31577923 "Enzymes, Plasma proteins, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 324.9;Plasma cells: 400.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045089, HPA056062" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "HPA045089: AB_10962054, HPA056062: AB_2683022" "unprognostic (8.03e-2)" "unprognostic (2.11e-2)" "unprognostic (5.03e-2)" "unprognostic (1.59e-1)" "unprognostic (2.82e-1)" "unprognostic (5.87e-3)" "prognostic unfavorable (1.95e-5)" "unprognostic (2.66e-2)" "unprognostic (2.14e-2)" "unprognostic (2.55e-1)" "unprognostic (2.30e-1)" "unprognostic (8.10e-2)" "prognostic unfavorable (4.64e-12)" "unprognostic (3.77e-2)" "unprognostic (1.57e-1)" "unprognostic (1.85e-1)" "unprognostic (8.17e-2)" 78.6 102.9 10.5 60.9 13.5 61.7 63.4 13.6 15.7 100.0 42.4 54.5 52.6 72.9 111.4 128.6 70.4 46.7 55.9 12.5 17.1 61.4 136.1 83.7 40.7 17.8 17.9 59.2 241.1 68.8 90.0 64.6 17.4 66.0 44.4 20.8 217.7 80.3 44.6 51.6 52.1 49.1 14.2 70.2 92.5 21.9 23.9 30.5 74.7 14.1 54.2 64.9 72.2 20.9 143.8 147.6 56.6 87.7 260.2 163.5 197.6 239.0 221.3 159.7 162.8 287.3 166.8 90.4 312.8 262.7 209.7 253.8 74.9 162.0 97.7 46.2 112.0 201.3 99.7 179.3 287.0 118.1 78.1 152.5 103.5 133.7 182.7 159.0 124.5 56.0 90.2 364.0 148.8 170.3 100.0 84.0 67.8 234.9 248.5 63.6 272.6 436.5 154.4 75.6 76.3 90.4 243.5 234.9 199.2 56.4 182.0 109.5 153.3 243.1 129.8 246.3 136.2 225.5 145.5 71.7 328.7 413.0 219.4 117.7 380.9 190.8 116.7 372.6 159.7 91.9 108.0 112.9 260.8 74.4 70.6 84.1 282.8 117.5 363.7 271.9 104.1 374.1 10.5 13.5 13.6 15.7 12.5 17.1 17.8 17.9 17.4 14.2 23.9 20.9 67.4 51.3 55.4 23.8 78.2 33.4 59.0 127.8 31.3 45.4 65.6 49.1 13.6 71.4 102.2 53.3 123.0 154.0 70.7 115.2 13.7 145.6 15.5 55.0 111.5 60.9 61.5 38.9 40.5 169.7 139.0 93.2 80.0 128.4 42.4 55.5 53.2 86.4 324.9 43.7 39.2 134.5 63.1 81.2 83.1 15.9 60.6 106.1 65.8 28.1 77.4 52.2 53.5 33.7 23.8 144.3 81.2 43.6 400.6 92.4 54.8 51.0 49.3 44.8 32.9 49.2 79.2 26.1 26.4 60.0 35.4 213.6 60.1 97.2 70.8 69.3 HSD17B2 "HSD17, SDR9C2" ENSG00000086696 "Hydroxysteroid 17-beta dehydrogenase 2" P37059 16 82035004-82098534 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 429.0;liver: 217.9;placenta: 381.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 155.8;Distal enterocytes: 203.4;Hepatocytes: 121.9;Paneth cells: 284.2;Proximal enterocytes: 390.7" "Group enriched" "Detected in many" 4 "liver cancer: 10.9;pancreatic cancer: 6.5;stomach cancer: 4.2;urothelial cancer: 5.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 57.9;Hep G2: 47.5;hTERT-HME1: 27.1;OE19: 87.1;RT4: 96.8;TIME: 54.0" "Group enriched" "Detected in some" 5 "midbrain: 2.2;pons and medulla: 3.4" "Not detected" "Not detected" "HPA021826, HPA050235" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "Endoplasmic reticulum" "HPA021826: AB_10961148, HPA050235: AB_2681059" "unprognostic (1.50e-1)" "unprognostic (2.53e-2)" "unprognostic (1.42e-1)" "unprognostic (6.48e-2)" "unprognostic (2.58e-1)" "unprognostic (1.77e-1)" "unprognostic (4.29e-2)" "unprognostic (2.60e-1)" "unprognostic (7.35e-2)" "unprognostic (6.05e-3)" "unprognostic (4.98e-2)" "unprognostic (7.35e-2)" "unprognostic (6.31e-4)" "unprognostic (5.39e-2)" "unprognostic (1.14e-1)" "unprognostic (4.30e-2)" "prognostic favorable (3.83e-4)" 1.6 0.0 0.4 4.2 0.2 0.7 26.4 0.9 0.4 4.3 0.2 74.8 429.0 1.2 0.1 9.6 0.1 21.1 0.2 0.3 0.2 9.6 217.9 2.3 0.3 0.1 0.0 0.3 23.2 0.0 1.2 381.8 0.1 2.0 56.9 17.4 22.1 0.2 0.1 4.2 188.6 2.4 0.0 0.2 20.1 0.3 0.1 0.4 0.1 0.0 3.4 78.6 1.4 0.3 0.4 0.1 0.4 0.0 0.0 0.7 0.7 0.2 57.9 0.0 0.0 10.9 1.7 0.1 11.4 0.0 0.1 0.4 0.0 2.4 0.0 0.1 0.1 0.3 0.3 47.5 0.4 0.3 0.3 0.0 3.1 0.0 27.1 0.6 0.9 0.1 0.1 0.4 8.6 0.1 0.0 0.9 0.2 87.1 21.4 0.1 0.2 1.3 1.0 96.8 0.4 1.5 0.0 2.7 0.2 0.0 0.1 0.1 54.0 0.6 0.5 0.3 0.0 0.2 0.2 0.3 0.0 0.2 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.1 0.1 0.2 0.0 0.0 0.4 0.2 0.9 0.4 0.3 0.2 0.1 0.0 0.1 0.0 0.1 0.3 1.0 3.2 3.9 0.3 0.7 0.4 2.7 16.4 2.2 0.5 45.7 12.3 0.6 155.8 21.4 0.0 0.0 2.7 0.3 203.4 0.0 73.6 0.5 5.9 5.4 21.3 3.0 2.7 0.1 6.0 1.8 38.3 15.3 41.3 0.0 0.0 2.5 121.9 3.5 0.0 0.1 26.3 6.1 3.1 0.0 0.9 0.0 0.4 1.8 0.0 0.0 45.1 0.0 0.0 0.1 20.1 284.2 0.0 0.1 2.7 390.7 1.4 5.6 0.7 0.0 0.4 2.0 0.0 0.1 0.8 1.1 6.4 0.7 0.0 47.1 14.8 HSP90B1 "GP96, GRP94, TRA1" ENSG00000166598 "Heat shock protein 90 beta family member 1" P14625 12 103930107-103953931 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Plasma cells: 4874.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003901, CAB005224, HPA008424, CAB078151" Enhanced Enhanced "Endoplasmic reticulum" "Intracellular and membrane" NA NA 330000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 12: NES - Nervous system development" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "CAB005224: AB_2119181, CAB078151: AB_2665765, HPA003901: AB_1851181, HPA008424: AB_1851184" "unprognostic (1.03e-1)" "unprognostic (3.44e-2)" "unprognostic (1.18e-1)" "unprognostic (5.70e-2)" "unprognostic (1.17e-2)" "unprognostic (7.14e-3)" "unprognostic (3.00e-2)" "unprognostic (7.22e-2)" "unprognostic (8.77e-2)" "unprognostic (8.30e-2)" "unprognostic (2.76e-1)" "unprognostic (1.43e-2)" "prognostic unfavorable (1.03e-10)" "unprognostic (2.95e-1)" "unprognostic (2.39e-1)" "unprognostic (1.24e-1)" "unprognostic (1.28e-2)" 330.4 340.6 166.0 423.5 183.7 438.9 341.8 185.3 234.2 363.2 225.6 340.5 261.4 302.2 1032.5 157.5 305.5 218.9 309.5 164.4 206.2 317.1 736.4 271.1 245.9 205.0 191.3 302.6 397.1 336.0 247.2 521.1 201.6 360.2 387.5 185.6 254.9 382.8 87.5 120.0 269.5 385.7 188.8 322.4 297.6 180.7 196.5 228.2 1411.8 91.2 328.0 356.6 164.6 237.3 856.5 459.9 926.2 940.0 960.1 897.5 1229.9 1449.4 1133.4 776.0 1038.1 839.1 805.3 243.8 1102.2 1579.2 995.1 583.2 934.6 1578.9 1063.2 607.3 307.4 684.5 447.6 861.0 1457.4 702.1 514.6 519.6 690.9 920.0 1342.8 2643.7 1513.9 293.8 560.0 914.8 1039.9 314.7 409.2 768.3 756.9 925.5 544.5 372.2 597.1 1079.2 1064.3 527.1 271.5 645.7 889.2 912.0 932.7 1468.4 743.9 1016.2 854.4 566.1 476.0 462.8 607.9 945.5 949.0 455.6 1106.9 494.7 904.5 113.8 81.3 30.3 199.7 88.6 244.9 108.5 118.5 187.8 111.8 71.1 75.9 133.8 18.7 199.3 83.3 322.7 81.1 188.5 166.0 183.7 185.3 234.2 164.4 206.2 205.0 191.3 201.6 188.8 196.5 237.3 507.5 237.2 373.8 28.7 646.0 309.3 905.1 743.6 196.9 50.3 261.4 334.0 687.8 235.9 475.3 257.5 156.4 568.4 480.6 424.0 56.7 471.2 89.6 570.8 751.1 439.6 406.6 213.5 34.0 250.4 1081.0 714.0 390.9 690.9 405.3 500.6 446.9 891.9 553.1 77.4 41.9 631.5 238.0 300.1 309.8 47.0 563.2 378.4 421.6 52.5 240.5 141.0 199.8 30.2 61.3 321.8 419.1 337.7 4874.6 760.6 246.1 271.4 404.2 111.6 216.9 325.7 569.3 489.0 154.4 196.3 260.7 921.0 316.0 542.6 494.6 620.0 IER3IP1 ENSG00000134049 "Immediate early response 3 interacting protein 1" Q9Y5U9 18 47152834-47176364 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Diabetes mellitus, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 357.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA010027 Supported Supported "Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Endoplasmic reticulum" "HPA010027: AB_1079098" "unprognostic (6.13e-2)" "unprognostic (2.96e-2)" "unprognostic (3.82e-2)" "unprognostic (1.45e-2)" "unprognostic (1.11e-3)" "unprognostic (2.41e-1)" "prognostic unfavorable (6.47e-6)" "unprognostic (9.86e-2)" "unprognostic (5.13e-2)" "prognostic favorable (8.59e-4)" "unprognostic (6.44e-2)" "unprognostic (6.24e-3)" "unprognostic (1.53e-3)" "unprognostic (8.55e-2)" "unprognostic (2.71e-2)" "unprognostic (8.75e-2)" "unprognostic (1.27e-3)" 13.7 17.2 8.1 11.8 8.2 14.5 14.2 11.1 10.0 10.5 11.2 14.1 16.9 11.2 10.9 12.0 9.0 10.2 17.0 8.2 9.1 31.4 19.5 12.3 11.4 8.8 8.9 11.6 13.7 19.2 15.5 10.9 9.0 13.9 13.0 14.1 15.0 7.9 31.1 13.8 15.7 9.5 8.0 11.1 15.9 9.3 8.9 11.1 15.9 21.7 10.6 13.9 11.0 8.9 27.1 15.3 22.9 20.5 30.5 33.8 15.9 62.7 30.5 30.6 32.2 12.5 22.7 26.5 19.3 28.1 25.0 32.3 21.8 22.1 33.2 43.5 19.5 23.3 23.0 38.2 32.5 70.5 33.2 26.8 27.7 27.6 20.6 28.9 26.7 23.7 19.4 39.7 33.0 15.0 25.1 33.7 11.6 11.5 18.4 24.7 35.9 37.9 31.2 26.0 26.4 29.4 21.5 18.1 38.8 16.4 18.0 40.1 38.7 45.2 23.3 22.0 34.7 56.9 66.4 27.9 35.3 44.4 37.2 15.9 17.2 16.1 25.0 16.6 22.2 18.9 21.1 21.5 16.6 20.9 19.6 20.8 1.9 17.3 17.5 34.5 23.6 19.3 8.1 8.2 11.1 10.0 8.2 9.1 8.8 8.9 9.0 8.0 8.9 8.9 80.8 86.6 51.8 7.8 58.9 0.0 64.6 0.0 73.4 48.0 96.0 51.4 63.1 97.2 19.2 51.5 8.4 104.9 61.3 35.6 140.8 124.3 18.4 49.5 47.7 70.8 37.6 51.3 15.7 138.9 126.3 76.2 57.6 55.6 13.9 40.0 83.6 138.8 108.9 40.4 17.4 69.1 0.0 63.6 0.0 13.3 84.8 54.8 0.0 12.2 79.4 69.6 86.5 16.1 19.1 139.3 50.1 48.5 158.8 117.3 125.0 357.0 26.2 48.0 52.6 40.4 61.6 163.3 158.9 88.1 0.0 177.2 54.4 36.7 62.2 109.4 IGFBP2 IBP2 ENSG00000115457 "Insulin like growth factor binding protein 2" P18065 2 216632828-216664436 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth regulation" "Growth factor binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 956.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 1379.1;Granulosa cells: 1649.7;Hepatocytes: 658.6;Theca cells: 2199.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 2139.8;HMC-1: 5110.0;NB-4: 1106.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077723 Approved "Endoplasmic reticulum" "Secreted to blood" NA NA 303000000 810000000 "Cluster 48: NK-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" "Endoplasmic reticulum" "HPA077723: AB_2686853" "unprognostic (2.58e-1)" "unprognostic (5.95e-2)" "unprognostic (1.94e-1)" "unprognostic (3.32e-3)" "unprognostic (9.50e-3)" "unprognostic (2.36e-2)" "unprognostic (2.06e-1)" "unprognostic (9.11e-3)" "prognostic unfavorable (2.43e-4)" "unprognostic (2.34e-1)" "unprognostic (1.63e-3)" "unprognostic (1.82e-1)" "prognostic unfavorable (2.22e-5)" "unprognostic (5.04e-2)" "unprognostic (1.07e-1)" "unprognostic (5.83e-2)" "unprognostic (1.22e-1)" 219.5 58.8 15.9 28.3 14.8 21.4 90.5 15.6 30.2 86.9 123.3 85.5 76.8 232.5 59.9 145.6 157.0 26.9 169.2 15.6 16.3 187.3 607.7 71.0 8.8 15.3 21.7 281.7 956.0 12.4 66.9 81.0 19.3 217.3 35.0 2.4 76.4 196.2 23.3 30.8 44.6 49.7 13.2 398.9 492.2 58.0 16.0 33.6 57.8 21.9 14.5 132.6 97.4 13.2 0.1 52.3 402.1 396.3 2139.8 652.9 8.5 125.2 61.9 6.1 0.6 1.2 1.5 0.1 171.7 0.8 15.2 11.5 145.4 156.9 0.6 0.8 84.9 91.3 0.2 26.3 53.3 38.6 5110.0 219.3 15.8 2.5 7.1 12.5 0.2 184.7 3.9 11.7 2.8 103.1 162.8 1106.5 437.4 98.2 4.8 139.2 9.1 2.0 2.0 117.1 84.1 443.4 0.3 3.4 2.6 362.2 332.4 67.3 0.5 1.6 2.4 1.6 6.2 6.2 0.9 9.7 6.0 177.4 478.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 15.9 14.8 15.6 30.2 15.6 16.3 15.3 21.7 19.3 13.2 16.0 13.2 354.3 3.2 0.6 2.0 3.3 13.8 534.0 238.2 19.4 0.2 79.0 498.0 12.5 11.5 40.1 264.8 2.1 1.8 5.4 86.4 29.4 3.0 1.0 153.2 1379.1 149.2 321.0 31.1 4.5 128.4 7.7 296.7 411.8 176.0 4.5 1649.7 92.1 658.6 5.3 0.0 0.8 191.6 54.9 24.1 5.0 4.9 5.6 21.8 3.6 13.1 1.3 3.6 3.1 1.0 1.0 60.7 51.3 79.4 0.4 255.7 4.2 1.2 195.9 1.7 105.2 17.9 435.7 6.0 35.8 103.3 5.5 2.2 16.0 2199.1 133.8 304.0 IGLL1 "14.1, CD179B, IGL5, IGLL, IGVPB" ENSG00000128322 "Immunoglobulin lambda like polypeptide 1" P15814 22 23573125-23580302 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 70.0;testis: 25.2" "Group enriched" "Detected in some" 6 "Early spermatids: 78.0;Late spermatids: 140.7;Melanocytes: 119.2" "Group enriched" "Detected in some" 5 "endometrial cancer: 0.5;lung cancer: 0.5;stomach cancer: 2.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "memory B-cell: 12.0;naive B-cell: 14.8" "Lineage enriched" "Detected in many" 11 "B-cells: 14.8" "Cell line enriched" "Detected in some" 32 "REH: 787.7" "HPA051134, HPA071406" Enhanced Approved "Endoplasmic reticulum" "Secreted to blood" NA NA 48000000000 "Cluster 24: B-cells - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 14: REH - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" "Endoplasmic reticulum" "HPA051134: AB_2681356, HPA071406: AB_2686393" "unprognostic (6.21e-2)" "unprognostic (5.12e-2)" "unprognostic (7.31e-2)" "unprognostic (4.75e-2)" "unprognostic (1.56e-1)" "unprognostic (5.91e-6)" "unprognostic (1.08e-1)" "unprognostic (5.27e-2)" "unprognostic (6.17e-3)" "unprognostic (5.89e-2)" "unprognostic (9.07e-2)" "unprognostic (1.99e-4)" "unprognostic (2.35e-2)" "unprognostic (5.16e-1)" "unprognostic (2.28e-2)" "unprognostic (1.21e-2)" 0.0 0.0 0.3 0.3 0.3 70.0 0.0 0.3 0.4 0.0 0.4 0.1 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.4 0.3 0.2 0.0 0.1 1.4 0.3 0.2 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.4 0.2 25.2 0.2 10.1 0.0 0.0 1.9 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 24.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.4 0.0 0.0 14.3 2.6 0.0 0.0 0.0 787.7 0.3 17.3 0.0 0.0 0.4 0.0 0.0 0.9 0.0 0.0 0.1 6.2 0.0 0.0 0.3 0.3 0.0 0.6 0.1 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 0.0 14.8 0.0 0.0 0.0 0.0 0.0 1.3 0.0 1.8 0.3 0.3 0.3 0.4 0.4 0.3 0.3 0.2 0.3 0.2 0.2 0.3 0.4 0.0 0.0 0.0 0.8 0.3 0.2 0.0 0.0 0.0 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 3.9 0.0 78.0 0.2 0.3 0.3 0.0 10.5 0.3 0.0 0.4 0.6 0.0 0.5 0.0 0.2 0.7 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.0 140.7 1.2 0.4 119.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.4 0.3 0.0 6.2 0.0 0.0 0.0 1.5 0.3 17.1 0.6 0.0 0.3 0.0 17.9 0.1 0.0 0.2 IKBIP "FLJ31051, IKIP" ENSG00000166130 "IKBKB interacting protein" Q70UQ0 12 98613405-98645113 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 28.1" "Lineage enriched" "Detected in all" 4 "granulocytes: 28.1" "Cell line enhanced" "Detected in all" "BJ: 206.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038677, HPA038678, HPA061541" Enhanced Enhanced "Endoplasmic reticulum" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA038677: AB_2676146, HPA038678: AB_10672723, HPA061541: AB_2684555" "unprognostic (3.06e-1)" "unprognostic (1.06e-3)" "unprognostic (2.13e-1)" "unprognostic (4.34e-2)" "unprognostic (1.94e-3)" "unprognostic (1.65e-2)" "prognostic unfavorable (4.00e-5)" "unprognostic (6.28e-3)" "unprognostic (1.78e-1)" "unprognostic (3.83e-1)" "unprognostic (7.37e-2)" "unprognostic (2.26e-1)" "prognostic unfavorable (4.60e-9)" "unprognostic (7.37e-2)" "unprognostic (1.66e-1)" "unprognostic (3.46e-1)" "unprognostic (3.16e-2)" 14.0 7.1 2.3 15.3 2.8 5.1 10.1 2.3 3.1 12.6 5.0 6.6 4.1 10.3 5.8 4.8 6.7 12.9 9.3 2.3 2.9 8.3 10.3 11.0 12.6 3.2 2.7 5.9 5.8 4.2 7.7 26.8 3.2 6.8 7.0 1.2 6.1 7.4 2.6 3.1 5.7 16.0 2.9 11.8 5.6 4.6 3.1 11.6 9.3 4.8 9.6 17.1 7.4 3.7 13.0 39.8 43.5 28.4 102.8 105.8 39.4 206.0 124.7 53.3 67.2 8.8 12.4 42.4 35.5 128.7 37.1 26.7 17.5 80.5 90.1 12.4 26.7 16.2 23.9 59.8 39.3 30.2 31.1 81.1 16.6 62.4 54.5 95.3 75.3 7.8 25.5 16.0 133.3 11.8 14.0 68.7 16.9 10.2 33.5 11.9 64.0 21.7 88.9 14.6 6.6 20.8 58.9 4.1 34.1 73.6 13.1 37.0 71.6 115.7 41.3 50.5 53.9 17.2 20.1 31.8 33.3 27.2 85.1 11.4 6.4 19.3 2.8 4.9 3.3 5.9 1.8 2.9 5.4 3.8 2.0 2.0 28.1 5.0 5.7 3.7 2.6 1.8 2.3 2.8 2.3 3.1 2.3 2.9 3.2 2.7 3.2 2.9 3.1 3.7 44.9 12.8 15.7 1.6 34.4 7.6 15.5 55.6 21.6 2.8 7.9 22.4 3.0 0.0 18.7 3.7 4.2 35.5 32.5 2.3 11.7 10.5 2.8 7.9 47.4 47.7 0.0 19.8 5.9 5.8 65.3 47.0 2.6 4.4 20.8 32.7 44.3 8.4 45.7 3.3 3.3 4.8 12.2 31.2 34.1 3.6 30.7 35.4 14.2 14.0 40.4 2.0 37.0 11.6 2.2 5.1 3.1 17.0 74.8 7.6 1.0 10.1 6.3 2.6 39.5 27.8 46.8 32.1 16.0 9.0 7.2 10.1 23.6 25.3 2.9 6.5 IL18BP IL18BPa ENSG00000137496 "Interleukin 18 binding protein" O95998 11 71998613-72005715 "Disease related genes, Metabolic proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 49.2" "Cell type enhanced" "Detected in many" "Adipocytes: 14.0;Exocrine glandular cells: 13.6;Kupffer cells: 14.2;Langerhans cells: 12.9;Macrophages: 15.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025980, HPA041061" Enhanced Approved "Endoplasmic reticulum" "Secreted to blood" NA NA 3070000 16000000 "Cluster 52: Eosinophils - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "CAB025980: , HPA041061: AB_2677280" "unprognostic (2.66e-3)" "unprognostic (2.04e-3)" "unprognostic (9.14e-3)" "unprognostic (1.70e-2)" "unprognostic (5.58e-3)" "unprognostic (7.75e-2)" "unprognostic (1.41e-1)" "unprognostic (6.20e-2)" "unprognostic (1.19e-2)" "unprognostic (1.75e-3)" "unprognostic (1.74e-1)" "unprognostic (1.51e-1)" "prognostic unfavorable (2.93e-6)" "unprognostic (1.19e-1)" "unprognostic (4.14e-2)" "unprognostic (6.76e-2)" "unprognostic (1.93e-2)" 14.4 18.4 6.0 25.0 6.3 7.9 13.6 7.1 9.1 12.5 4.9 12.7 8.3 10.4 3.5 6.4 10.1 8.1 10.9 5.8 8.3 24.9 15.0 31.1 26.2 8.7 7.8 11.1 8.4 2.5 10.7 17.1 9.0 16.5 11.0 3.8 8.9 4.2 5.0 7.4 17.2 13.5 6.1 49.2 10.2 6.1 8.5 6.5 12.6 2.4 11.9 12.2 8.5 7.3 1.7 2.3 5.1 2.9 1.0 1.6 5.9 3.3 1.8 3.0 4.0 11.7 2.4 1.2 2.2 1.3 3.4 4.0 2.5 2.4 2.0 2.5 3.8 4.5 7.6 3.7 1.3 2.4 12.3 2.4 2.3 2.4 1.2 3.5 6.3 7.9 7.4 2.0 1.8 3.2 3.8 5.7 3.6 1.9 2.2 6.1 5.4 1.9 2.1 4.4 2.8 5.3 3.0 4.2 3.7 4.8 3.6 2.7 13.6 4.2 3.5 5.1 1.9 3.3 1.8 2.1 1.7 11.5 2.3 7.0 20.2 56.1 52.5 72.9 23.9 31.9 27.5 31.6 36.9 20.2 22.5 32.5 8.6 5.2 60.9 53.7 15.1 39.8 6.0 6.3 7.1 9.1 5.8 8.3 8.7 7.8 9.0 6.1 8.5 7.3 14.0 6.4 3.3 0.7 8.0 2.0 0.4 0.7 0.0 3.3 2.1 1.9 1.8 1.5 1.0 0.0 10.4 1.0 7.2 0.5 0.0 3.0 0.0 1.1 1.9 11.1 0.0 0.8 0.7 13.6 1.4 3.4 1.1 1.8 7.6 2.2 10.4 0.5 11.2 3.3 0.5 0.8 0.0 14.2 12.9 0.0 0.9 15.4 0.0 1.0 4.6 1.1 7.2 0.5 0.0 5.4 0.2 0.7 2.3 1.0 1.1 1.9 1.8 3.7 0.0 1.8 1.6 0.7 0.5 0.6 2.0 0.8 6.4 1.6 0.8 0.2 ITFG2 "FGGAP1, MDS028" ENSG00000111203 "Integrin alpha FG-GAP repeat containing 2" Q969R8 12 2812622-2859791 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038664, HPA038665" Uncertain Uncertain "Endoplasmic reticulum" NA No "Cluster 27: Non-specific - Gene expression" "Cluster 1: Thyroid gland - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Endoplasmic reticulum" "HPA038664: AB_10672722, HPA038665: AB_2676138" "unprognostic (5.70e-2)" "unprognostic (2.74e-1)" "unprognostic (1.73e-2)" "unprognostic (2.96e-1)" "unprognostic (2.46e-2)" "unprognostic (6.27e-2)" "unprognostic (1.47e-2)" "unprognostic (3.64e-2)" "unprognostic (1.60e-2)" "unprognostic (4.36e-2)" "unprognostic (5.05e-3)" "unprognostic (8.40e-2)" "unprognostic (2.60e-1)" "unprognostic (4.24e-1)" "unprognostic (5.89e-1)" "unprognostic (4.35e-2)" "unprognostic (7.43e-2)" 12.8 15.6 6.0 11.4 8.1 14.4 14.0 10.2 8.1 17.7 10.7 14.2 12.4 18.7 14.5 13.1 17.1 8.9 12.1 5.9 9.2 16.4 12.2 15.0 15.9 7.7 7.9 28.9 22.1 28.1 14.1 14.5 8.1 13.9 15.0 8.1 17.9 15.6 8.3 11.7 14.5 13.4 6.2 19.6 16.1 5.1 8.0 18.1 26.7 9.7 15.8 14.7 14.9 11.8 7.3 10.6 11.9 9.7 10.2 11.6 11.0 15.9 9.0 18.9 13.8 22.7 17.6 16.5 4.4 15.0 9.4 9.1 18.5 15.9 14.1 14.7 10.6 23.1 12.7 9.1 18.8 21.7 12.0 15.7 18.4 17.3 26.4 15.5 13.1 15.6 12.8 17.3 10.9 21.9 31.3 12.6 24.6 16.5 8.0 15.6 13.3 9.5 11.3 12.3 5.7 18.3 19.5 17.1 7.2 16.2 10.6 9.9 13.4 12.4 7.4 12.0 30.8 2.2 1.4 25.0 8.0 12.4 12.8 4.0 16.6 8.4 19.2 22.2 18.0 25.8 14.7 19.0 19.6 24.2 19.8 18.6 1.9 23.4 35.6 14.6 13.2 16.5 6.0 8.1 10.2 8.1 5.9 9.2 7.7 7.9 8.1 6.2 8.0 11.8 11.1 12.8 17.9 12.7 35.9 3.3 9.8 9.3 10.2 39.8 16.5 15.6 17.1 18.6 12.1 12.9 64.6 28.1 27.6 13.0 11.7 9.2 46.3 13.0 19.1 10.5 9.5 17.9 13.6 7.2 8.9 15.0 23.0 13.2 6.3 18.7 12.1 11.3 13.4 32.0 15.2 15.2 8.2 12.0 5.1 12.1 16.8 11.0 1.8 8.4 16.8 10.0 42.2 10.1 25.8 7.2 14.4 13.2 19.6 9.1 20.5 6.1 8.7 56.0 6.6 11.7 16.9 13.2 20.0 14.3 4.0 17.4 24.3 22.2 19.5 5.9 JSRP1 "FLJ32416, JP-45" ENSG00000167476 "Junctional sarcoplasmic reticulum protein 1" Q96MG2 19 2252252-2269759 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "skeletal muscle: 335.4" "Cell type enhanced" "Detected in many" "B-cells: 31.7;Melanocytes: 46.2;Plasma cells: 139.4;Skeletal myocytes: 132.6" "Cancer enriched" "Detected in many" 4 "endometrial cancer: 11.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 10 "naive B-cell: 2.6" "Lineage enriched" "Detected in single" 10 "B-cells: 2.6" "Cell line enhanced" "Detected in some" "Karpas-707: 164.1;RPMI-8226: 109.8;U-266/70: 444.1;U-266/84: 57.8" "Group enriched" "Detected in many" 6 "amygdala: 8.4;basal ganglia: 11.6;cerebral cortex: 9.9;hippocampal formation: 4.4;white matter: 5.1" "Not detected" "Not detected" HPA044741 Enhanced Approved "Endoplasmic reticulum" NA NA 13000 "Cluster 24: B-cells - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "HPA044741: AB_10794295" "unprognostic (9.41e-3)" "unprognostic (1.52e-2)" "unprognostic (1.39e-1)" "unprognostic (5.85e-2)" "unprognostic (2.15e-1)" "unprognostic (9.69e-2)" "unprognostic (1.58e-2)" "unprognostic (4.64e-2)" "unprognostic (4.27e-2)" "unprognostic (1.80e-2)" "unprognostic (2.44e-2)" "unprognostic (1.87e-2)" "unprognostic (8.64e-5)" "unprognostic (3.63e-1)" "unprognostic (4.43e-1)" "unprognostic (2.07e-1)" "unprognostic (2.71e-1)" 0.2 0.1 0.4 0.9 0.4 0.4 0.4 0.4 0.4 0.3 0.2 1.5 2.9 0.1 0.0 0.3 0.3 0.1 0.0 0.3 0.4 0.6 0.3 0.7 0.5 0.3 0.3 0.1 0.5 0.0 0.3 0.0 0.3 1.9 0.1 0.0 8.9 0.0 335.4 0.3 1.4 0.0 0.3 5.4 1.7 1.9 0.5 0.1 0.6 18.6 0.6 0.2 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.4 26.8 0.0 0.0 0.2 0.0 0.0 0.0 46.6 0.1 0.0 0.0 1.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 164.1 7.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 26.7 109.8 0.0 0.0 0.1 0.6 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 444.1 57.8 2.4 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.2 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.4 0.4 0.4 0.3 0.4 0.3 0.3 0.3 0.3 0.5 0.3 0.1 0.0 5.3 0.0 31.7 0.5 0.3 0.2 0.6 0.8 0.6 0.4 0.6 1.5 0.1 0.0 2.1 0.2 0.7 1.7 0.0 1.8 19.0 0.7 0.3 0.3 5.4 1.3 0.2 1.0 0.6 1.1 1.5 1.1 6.3 2.9 0.7 0.6 0.5 0.0 0.1 2.3 2.0 1.3 2.2 18.2 0.6 1.1 46.2 0.0 0.0 0.5 1.0 0.0 0.1 1.0 0.3 0.0 139.4 0.3 0.6 0.4 1.7 0.5 0.0 132.6 0.6 7.6 1.9 0.2 1.0 0.3 5.0 0.5 0.7 0.2 KCNQ2 "BFNC, EBN, EBN1, ENB1, HNSPC, KCNA11, Kv7.2" ENSG00000075043 "Potassium voltage-gated channel subfamily Q member 2" O43526 20 63400208-63472677 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 91.9" "Cell type enhanced" "Detected in some" "Early spermatids: 16.5;Excitatory neurons: 61.7;Horizontal cells: 13.5;Inhibitory neurons: 37.5;Oligodendrocyte precursor cells: 50.8;Spermatogonia: 28.3" "Cancer enriched" "Detected in some" 9 "glioma: 8.7" "Group enriched" "Detected in many" 4 "amygdala: 55.7;basal ganglia: 37.2;cerebellum: 27.8;cerebral cortex: 91.9;hippocampal formation: 68.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 21.2;AN3-CA: 35.0;NTERA-2: 19.3;SCLC-21H: 67.8;SH-SY5Y: 119.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016642, HPA057112" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Endoplasmic reticulum" "HPA016642: AB_1855555, HPA057112: AB_2683339" "unprognostic (2.35e-1)" "unprognostic (1.41e-1)" "unprognostic (2.22e-4)" "unprognostic (8.21e-6)" "unprognostic (6.18e-2)" "unprognostic (7.58e-2)" "unprognostic (6.06e-2)" "unprognostic (3.16e-1)" "unprognostic (1.73e-1)" "unprognostic (1.92e-1)" "unprognostic (9.96e-2)" "unprognostic (9.39e-2)" "unprognostic (1.43e-5)" "unprognostic (4.36e-2)" "unprognostic (1.02e-1)" "unprognostic (1.81e-1)" "unprognostic (2.70e-2)" 0.0 6.2 55.7 0.1 37.2 0.0 0.0 27.8 91.9 0.0 0.0 0.6 0.1 0.0 0.1 0.0 0.3 0.3 0.2 68.1 0.0 0.1 0.0 0.0 0.0 2.6 0.0 0.0 1.1 0.0 19.1 0.0 0.1 1.6 0.0 2.2 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.2 10.6 1.0 0.0 0.0 0.0 0.0 0.0 0.1 12.9 0.0 0.0 21.2 35.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.6 0.0 8.3 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 19.3 0.5 0.2 0.0 0.0 0.1 0.0 0.0 67.8 119.3 0.1 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 55.7 37.2 27.8 91.9 68.1 0.0 2.6 0.0 0.1 0.0 1.0 12.9 0.6 0.0 0.0 7.2 0.1 0.1 0.0 0.0 0.0 5.7 0.0 0.3 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 16.5 0.0 0.1 1.0 0.0 0.0 61.7 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 13.5 37.5 0.2 0.0 0.0 0.0 8.1 0.6 0.1 0.0 1.0 0.0 0.9 0.0 50.8 2.1 0.0 0.0 0.4 0.0 0.3 0.0 0.1 0.0 2.5 0.0 0.1 0.1 7.4 28.3 0.0 0.0 0.0 0.3 0.0 0.1 0.0 KDELR3 ENSG00000100196 "KDEL endoplasmic reticulum protein retention receptor 3" O43731 22 38468078-38483447 "Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 73.2;Fibroblasts: 54.7;Intestinal goblet cells: 70.6;Proximal enterocytes: 40.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC TERT1: 267.0;BJ: 180.5;BJ hTERT+: 182.0;fHDF/TERT166: 289.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043477, HPA076405" Uncertain Supported "Endoplasmic reticulum" No No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 4: Stomach - Digestion" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA043477: AB_10962952, HPA076405: AB_2686797" "unprognostic (1.76e-1)" "unprognostic (3.77e-2)" "unprognostic (1.81e-1)" "unprognostic (1.20e-2)" "unprognostic (2.90e-1)" "unprognostic (2.05e-2)" "prognostic unfavorable (1.19e-4)" "unprognostic (2.26e-1)" "unprognostic (1.91e-1)" "unprognostic (1.23e-1)" "unprognostic (9.25e-3)" "unprognostic (2.45e-1)" "prognostic unfavorable (6.05e-10)" "unprognostic (1.66e-1)" "unprognostic (1.46e-1)" "unprognostic (8.24e-2)" "unprognostic (2.07e-2)" 13.4 4.4 0.9 7.6 1.3 2.0 12.2 2.9 2.1 31.1 8.7 18.1 15.4 7.5 29.5 4.8 7.4 19.6 15.7 1.3 0.9 8.5 12.6 10.3 3.2 1.5 1.7 3.5 15.9 12.1 14.2 16.0 1.1 19.7 22.5 3.1 34.4 10.9 2.1 4.1 18.5 15.5 1.3 2.5 35.0 3.9 1.1 1.7 6.3 3.7 7.2 12.5 4.4 1.5 35.8 11.1 8.7 37.2 142.7 267.0 6.4 180.5 182.0 42.7 105.3 22.1 45.1 0.3 38.2 289.3 15.2 5.1 8.9 10.7 51.0 0.4 21.8 2.5 8.7 55.2 62.9 0.4 24.1 99.9 8.0 53.9 5.7 60.1 52.4 0.3 9.0 0.1 70.7 56.8 0.1 1.3 2.1 150.2 33.2 0.2 2.4 11.8 51.5 4.8 0.7 4.6 46.7 2.7 22.9 3.6 13.3 2.4 41.5 45.8 29.0 160.3 18.0 1.7 0.6 0.2 73.5 0.1 65.0 0.0 0.0 0.0 0.2 0.0 0.8 0.3 0.2 0.1 0.0 0.1 0.2 0.2 0.2 0.0 0.0 1.6 0.2 0.1 0.9 1.3 2.9 2.1 1.3 0.9 1.5 1.7 1.1 1.3 1.1 1.5 14.5 0.0 4.8 0.3 4.5 7.6 5.7 7.5 1.2 1.3 10.0 4.2 2.5 8.6 10.0 14.7 2.1 5.1 0.3 9.1 7.9 19.0 0.2 8.0 19.4 10.2 4.9 0.8 0.7 31.6 73.2 54.7 24.5 11.0 1.3 6.9 14.6 5.3 4.7 0.0 0.5 70.6 0.0 0.9 14.5 0.6 32.6 1.1 16.0 1.9 1.0 6.3 0.0 0.0 0.4 31.5 4.9 16.1 12.8 16.3 40.1 0.8 9.2 1.4 0.0 1.7 20.5 0.5 2.4 1.6 7.1 8.2 2.3 4.2 11.1 7.8 KTN1 "CG1, KIAA0004, KNT" ENSG00000126777 "Kinectin 1" Q86UP2 14 55559072-55701526 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003178, CAB015331, HPA017876" Enhanced Enhanced "Endoplasmic reticulum" NA NA 55000 "Cluster 6: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Endoplasmic reticulum" "CAB015331: , HPA003178: AB_1079218, HPA017876: AB_1852652" "unprognostic (7.00e-3)" "unprognostic (2.99e-2)" "unprognostic (8.60e-2)" "unprognostic (5.50e-2)" "unprognostic (2.49e-1)" "prognostic unfavorable (6.83e-5)" "prognostic unfavorable (3.76e-4)" "unprognostic (1.75e-1)" "unprognostic (1.21e-2)" "unprognostic (1.01e-1)" "unprognostic (9.08e-2)" "unprognostic (8.72e-2)" "prognostic favorable (1.01e-6)" "unprognostic (1.27e-1)" "unprognostic (2.75e-1)" "unprognostic (1.30e-1)" "unprognostic (1.04e-1)" 81.6 77.7 90.8 52.8 98.9 36.1 81.6 92.8 106.3 61.4 165.0 97.4 43.4 58.1 97.1 72.7 53.2 58.6 134.6 81.0 94.2 104.0 106.6 67.0 61.8 100.2 95.3 63.9 67.2 143.0 67.4 69.4 100.7 77.5 90.8 127.9 73.5 73.5 378.2 137.6 53.2 60.3 95.2 53.4 61.1 145.1 99.4 54.7 107.7 281.6 61.0 113.1 55.2 110.3 200.5 133.4 100.3 106.5 132.8 127.3 140.2 159.7 127.3 97.2 85.2 89.4 233.9 152.8 213.4 166.7 102.7 347.2 122.5 138.2 162.7 251.9 65.2 109.1 223.0 174.4 126.3 160.3 83.3 119.1 124.6 122.1 208.4 208.3 161.9 122.2 107.4 88.1 189.0 154.6 141.3 95.0 76.8 91.1 194.3 109.6 258.2 73.5 244.8 307.0 122.4 100.0 245.8 113.2 143.2 201.7 115.3 101.7 230.0 193.9 250.4 100.0 151.2 38.9 55.9 110.4 229.4 93.4 109.5 117.0 42.7 48.0 56.2 40.3 54.7 95.6 69.4 65.8 44.0 106.6 71.1 62.1 29.6 64.9 52.6 185.8 48.4 16.0 90.8 98.9 92.8 106.3 81.0 94.2 100.2 95.3 100.7 95.2 99.4 110.3 363.1 307.7 239.8 72.5 171.7 654.5 285.8 215.6 270.9 206.5 460.6 348.7 852.7 270.2 214.7 428.6 360.7 155.1 194.9 575.2 31.3 249.7 721.9 351.3 186.6 345.0 224.0 165.3 93.9 304.0 199.1 211.9 95.3 298.1 134.9 384.5 295.9 401.7 116.8 326.4 112.1 226.4 207.5 181.3 261.6 377.9 248.5 168.9 172.5 104.9 194.3 449.2 142.2 90.0 139.8 341.2 325.7 441.6 184.6 283.5 152.6 109.3 319.3 400.9 335.2 333.5 292.1 694.3 386.4 217.8 723.0 164.7 168.3 162.4 282.4 328.0 LAMA3 "BM600-150kDa, epiligrin, kalinin-165kDa, LAMNA, nicein-150kDa" ENSG00000053747 "Laminin subunit alpha 3" Q16787 18 23689453-23956222 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Epidermolysis bullosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 171.0;Gastric mucus-secreting cells: 138.1;Pancreatic endocrine cells: 585.5;Paneth cells: 170.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 40.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "HBEC3-KT: 1237.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA009309, CAB010757" Uncertain Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 1800000 "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Endoplasmic reticulum" "CAB010757: AB_477162, HPA009309: AB_1079224" "unprognostic (1.49e-2)" "unprognostic (2.14e-2)" "unprognostic (6.36e-2)" "unprognostic (3.82e-3)" "unprognostic (2.08e-1)" "unprognostic (1.11e-1)" "unprognostic (1.83e-1)" "unprognostic (2.28e-3)" "unprognostic (1.59e-1)" "unprognostic (7.09e-3)" "prognostic unfavorable (3.58e-6)" "unprognostic (1.98e-1)" "unprognostic (2.36e-1)" "unprognostic (3.15e-1)" "unprognostic (9.91e-3)" "unprognostic (3.98e-2)" "unprognostic (1.13e-1)" 10.0 1.2 8.3 8.5 3.6 0.1 20.3 2.8 5.9 15.4 5.4 13.6 17.8 15.6 4.7 14.5 12.0 7.4 4.2 4.1 3.5 3.2 1.7 20.9 4.1 3.8 5.9 5.7 4.7 10.9 3.0 24.8 3.6 12.2 8.4 3.7 21.3 13.5 2.0 32.1 19.7 6.9 3.5 0.8 31.8 3.3 4.3 9.5 2.3 1.7 4.1 12.2 23.1 2.9 140.5 15.7 0.1 0.1 6.9 1.3 0.3 2.6 1.8 1.3 1.7 5.4 159.5 0.1 17.3 1.8 0.4 248.5 0.2 1237.9 0.9 0.2 8.8 0.0 5.6 2.8 1.2 0.0 0.6 1.6 139.1 0.8 140.0 0.9 5.2 0.2 0.0 0.2 1.6 0.4 0.1 0.1 1.4 42.6 14.4 2.6 0.1 0.2 51.8 15.4 0.6 2.5 4.9 2.0 0.4 0.3 4.5 1.8 12.3 0.9 1.0 6.7 0.6 0.2 0.1 0.6 2.9 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.3 3.6 2.8 5.9 4.1 3.5 3.8 5.9 3.6 3.5 4.3 2.9 28.8 115.4 26.4 13.1 0.7 31.4 104.2 117.1 100.7 6.0 21.8 41.8 2.3 4.3 20.4 1.8 0.0 0.6 0.5 171.0 0.0 30.2 3.9 21.5 4.3 7.5 8.3 0.0 8.3 34.4 0.4 3.6 138.1 24.0 5.7 9.5 2.5 0.9 0.2 0.0 18.5 23.7 4.1 0.0 1.5 4.5 5.9 2.0 1.8 68.4 0.6 0.2 0.0 1.0 2.0 585.5 170.1 3.4 0.2 45.6 39.5 0.0 15.6 2.2 6.6 1.5 22.1 4.5 4.0 28.2 9.9 0.1 1.5 5.9 28.4 18.2 LCN2 "24p3, NGAL" ENSG00000148346 "Lipocalin 2" P80188 9 128149071-128153453 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Apoptosis, Immunity, Innate immunity, Ion transport, Iron transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 2768.7;gallbladder: 2223.2;salivary gland: 1308.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 4054.2;Club cells: 5757.0;Ductal cells: 6457.0;Pancreatic endocrine cells: 5424.3;Respiratory ciliated cells: 3161.5;Urothelial cells: 7112.9" "Cancer enhanced" "Detected in many" "stomach cancer: 944.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 88 "basophil: 9.8;neutrophil: 11.9;non-classical monocyte: 4.7" "Group enriched" "Detected in many" 83 "granulocytes: 11.9;monocytes: 4.7" "Group enriched" "Detected in many" 11 "CAPAN-2: 3623.8;EFO-21: 1450.9" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 5 "cerebellum: 149.7;spinal cord: 102.4" "HPA002695, CAB016549, CAB016550" Enhanced Supported "Endoplasmic reticulum" "Secreted in other tissues" NA NA 297000000 590000000 "Cluster 34: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Endoplasmic reticulum" "CAB016549: , CAB016550: , HPA002695: AB_1852758" "prognostic favorable (9.61e-4)" "unprognostic (1.71e-1)" "unprognostic (2.59e-1)" "unprognostic (7.38e-3)" "unprognostic (1.01e-2)" "unprognostic (4.66e-2)" "unprognostic (1.86e-1)" "unprognostic (1.01e-1)" "unprognostic (4.33e-1)" "unprognostic (1.79e-1)" "unprognostic (2.36e-2)" "unprognostic (2.83e-2)" "unprognostic (1.10e-3)" "unprognostic (6.15e-2)" "unprognostic (2.37e-1)" "unprognostic (3.15e-2)" "unprognostic (1.11e-2)" 4.9 3.6 0.0 125.5 0.1 2768.7 22.0 0.1 0.5 810.5 2.0 249.1 34.4 14.2 20.5 677.6 52.6 2223.2 3.1 0.0 0.1 31.6 67.8 76.1 1.1 0.3 0.1 1.1 74.8 7.3 21.2 2.6 0.3 74.5 131.0 0.0 1308.3 13.5 1.2 28.1 157.3 11.9 0.1 82.0 363.9 0.5 0.1 14.2 27.1 0.3 199.1 669.9 480.7 0.1 117.7 35.1 0.0 4.5 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.2 3623.8 0.2 1450.9 0.0 3.7 236.4 0.0 6.9 0.1 5.3 0.0 30.4 0.0 0.8 0.2 0.0 1.1 0.1 230.4 0.0 12.1 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.2 0.0 1.9 80.9 0.2 0.2 0.3 0.3 1.0 20.1 0.1 0.1 2.0 65.3 1.0 0.0 8.4 1.8 0.0 2.9 16.9 0.0 2.9 0.6 4.6 4.7 0.2 0.6 2.1 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.0 4.7 0.0 0.0 12.1 0.0 0.1 0.1 0.5 0.0 0.1 0.3 0.1 0.3 0.1 0.1 0.1 0.2 0.0 20.8 0.0 15.9 0.3 376.6 4054.2 1.8 0.0 38.1 29.3 0.2 1328.2 5757.0 138.0 0.0 0.8 1.2 315.6 0.0 6457.0 2.0 25.6 4.3 11.5 57.9 11.2 0.0 1837.0 0.3 12.2 237.0 52.3 13.4 0.0 2.2 43.2 0.6 0.0 0.0 264.3 956.2 2.7 0.0 15.8 3.4 34.9 0.0 0.0 60.3 0.0 1.0 0.0 0.0 5424.3 183.4 0.0 1.4 420.6 509.8 1.6 3161.5 0.0 0.0 0.0 337.7 0.0 0.3 51.1 0.0 0.3 7.7 0.0 475.5 7112.9 LIPM "bA304I5.1, LIPL3" ENSG00000173239 "Lipase family member M" Q5VYY2 10 88802730-88820546 "Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "skin 1: 28.0" "Cell type enriched" "Detected in single" 11 "Suprabasal keratinocytes: 1.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA071276 Approved "Endoplasmic reticulum" "Secreted in other tissues" NA NA "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "Endoplasmic reticulum" "HPA071276: " "unprognostic (7.72e-2)" "unprognostic (8.49e-4)" "unprognostic (1.42e-2)" "unprognostic (2.23e-4)" "unprognostic (6.70e-3)" "unprognostic (3.01e-3)" "unprognostic (5.75e-2)" "unprognostic (6.63e-2)" "unprognostic (5.61e-2)" "unprognostic (1.45e-2)" "prognostic unfavorable (6.47e-4)" "unprognostic (1.59e-2)" "unprognostic (5.93e-2)" "unprognostic (7.05e-3)" "unprognostic (4.17e-2)" "unprognostic (9.02e-2)" "unprognostic (9.70e-6)" 0.1 0.0 0.0 0.2 0.0 0.1 1.9 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 28.0 0.0 0.0 0.0 0.2 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 LOX ENSG00000113083 "Lysyl oxidase" P28300 5 122063195-122078413 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 27.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 67.1;Club cells: 38.4;Early spermatids: 41.9;Endometrial stromal cells: 34.0;Extravillous trophoblasts: 44.2;Fibroblasts: 79.1;Peritubular cells: 39.1;Smooth muscle cells: 32.7" "Cancer enhanced" "Detected in all" "renal cancer: 39.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 777.3;fHDF/TERT166: 1790.7;HSkMC: 356.3;U-138 MG: 475.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA043930 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 550000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA043930: AB_2678736" "unprognostic (5.10e-2)" "unprognostic (1.03e-2)" "unprognostic (6.99e-3)" "unprognostic (3.64e-2)" "unprognostic (9.86e-3)" "unprognostic (1.91e-1)" "prognostic unfavorable (7.38e-4)" "unprognostic (2.42e-3)" "unprognostic (3.06e-3)" "unprognostic (8.92e-2)" "unprognostic (3.21e-3)" "unprognostic (1.91e-1)" "prognostic unfavorable (3.93e-8)" "unprognostic (1.11e-3)" "unprognostic (9.92e-2)" "unprognostic (4.31e-2)" "prognostic unfavorable (3.32e-4)" 27.9 2.4 0.4 6.8 0.4 0.2 17.6 0.5 0.9 10.8 0.8 4.2 3.8 6.2 1.7 5.6 8.9 18.8 23.9 0.3 0.4 4.5 2.1 13.6 3.3 1.3 1.4 5.4 3.3 0.9 1.2 8.1 0.8 4.1 4.5 1.1 3.2 2.6 1.9 12.4 3.7 10.0 1.2 2.6 4.4 1.4 0.5 0.9 6.9 2.1 1.4 14.1 4.8 1.0 0.8 0.2 2.0 0.9 168.7 185.2 0.1 777.3 205.3 73.2 246.4 0.5 0.3 0.1 16.5 1790.7 3.7 0.2 4.5 3.5 196.4 0.1 2.0 0.0 16.3 9.3 203.4 0.4 0.1 356.3 4.4 137.6 7.4 329.3 95.3 0.1 0.0 0.1 83.6 0.0 0.1 0.3 6.4 0.1 1.9 0.1 7.4 0.9 4.9 0.5 0.5 4.2 72.1 0.1 12.9 29.8 0.6 0.6 6.8 475.5 23.2 272.8 9.3 0.0 0.1 0.2 207.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.5 0.9 0.3 0.4 1.3 1.4 0.8 1.2 0.5 1.0 20.0 9.6 1.1 0.0 0.2 7.8 1.9 67.1 0.0 0.6 1.3 1.1 2.1 0.0 38.4 0.0 0.0 0.8 0.1 0.0 0.0 7.2 41.9 8.4 34.0 9.4 0.0 0.0 0.3 0.6 44.2 79.1 0.0 6.6 0.0 0.1 10.8 0.5 2.2 1.7 2.0 0.0 2.0 0.8 21.6 5.0 14.0 1.3 5.4 1.9 0.6 0.0 0.0 0.0 0.0 1.3 0.0 39.1 0.3 2.8 0.0 0.1 8.3 1.7 19.7 1.1 32.7 0.8 0.6 1.8 10.7 4.8 1.1 0.4 0.1 0.9 LOXL1 "LOL, LOXL" ENSG00000129038 "Lysyl oxidase like 1" Q08397 15 73925989-73952137 "Disease related genes, Plasma proteins, Predicted secreted proteins" Oxidoreductase Glaucoma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 92.3;Extravillous trophoblasts: 145.8;Fibroblasts: 76.0;Smooth muscle cells: 32.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "T-reg: 3.4" "Lineage enriched" "Detected in single" 34 "T-cells: 3.4" "Cell line enhanced" "Detected in many" "BJ: 66.5;BJ hTERT+: 75.2;hTERT-RPE1: 73.7;U-87 MG: 61.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA042111, HPA063583" Approved Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" No No 280000 "Cluster 35: T-regs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA042111: AB_10794412, HPA063583: AB_2685050" "unprognostic (6.39e-2)" "unprognostic (1.23e-1)" "unprognostic (3.05e-2)" "unprognostic (3.61e-2)" "prognostic unfavorable (9.52e-5)" "unprognostic (7.95e-2)" "unprognostic (2.49e-1)" "unprognostic (2.44e-1)" "unprognostic (3.10e-1)" "unprognostic (1.57e-1)" "unprognostic (1.63e-1)" "unprognostic (9.83e-2)" "unprognostic (1.14e-3)" "unprognostic (4.51e-2)" "unprognostic (5.81e-2)" "unprognostic (1.41e-2)" "unprognostic (9.76e-2)" 12.4 3.1 1.4 5.4 0.8 0.8 6.8 0.2 1.4 12.7 12.3 10.2 1.9 16.0 1.4 4.7 8.3 5.0 27.9 1.7 1.9 8.7 1.5 10.1 4.4 1.4 1.7 8.0 3.3 2.2 9.2 8.0 1.1 15.3 1.4 0.0 7.6 11.9 3.8 6.4 5.6 4.9 0.8 3.2 7.8 2.4 1.9 0.9 5.2 1.9 2.3 16.6 14.8 0.6 3.3 0.0 0.9 0.0 45.6 54.8 2.2 66.5 75.2 27.6 48.7 1.3 1.7 0.0 12.1 49.1 6.9 19.9 0.3 0.2 6.5 0.0 4.3 0.2 2.0 0.3 6.2 0.0 0.1 45.0 0.0 20.8 0.2 73.7 1.0 1.2 0.0 0.3 33.3 2.4 0.4 1.3 6.3 4.4 45.1 0.0 38.7 0.6 2.5 12.0 5.5 0.0 2.0 0.4 0.0 6.5 0.4 0.0 4.9 53.8 47.0 42.8 25.8 0.2 0.0 0.0 61.9 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.9 0.0 1.3 0.7 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 3.4 0.2 1.4 0.8 0.2 1.4 1.7 1.9 1.4 1.7 1.1 0.8 1.9 0.6 4.1 0.0 0.6 3.3 0.1 5.9 7.6 6.0 4.0 0.9 2.3 4.8 92.3 2.8 0.9 9.2 0.0 2.2 0.6 0.1 3.9 5.2 1.7 9.2 8.0 4.1 3.5 0.0 0.5 1.3 145.8 76.0 8.6 9.3 1.3 5.5 12.1 0.1 6.6 0.0 0.4 0.6 2.0 0.0 6.2 1.3 9.9 0.9 10.6 0.0 0.1 6.4 0.0 1.5 0.3 12.2 0.1 21.1 0.1 4.8 0.4 2.5 1.2 0.4 0.0 6.0 32.7 8.9 4.9 2.4 3.4 5.1 3.4 0.3 1.1 5.0 LRPAP1 "A2MRAP, HBP44, RAP" ENSG00000163956 "LDL receptor related protein associated protein 1" P30533 4 3503612-3532446 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Heparin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 584.3;Syncytiotrophoblasts: 693.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008001, CAB025518" Enhanced Supported Supported "Endoplasmic reticulum" NA NA 810000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "Endoplasmic reticulum" "CAB025518: , HPA008001: AB_1853292" "unprognostic (3.20e-3)" "unprognostic (7.01e-2)" "unprognostic (2.30e-1)" "unprognostic (2.22e-2)" "unprognostic (1.37e-2)" "unprognostic (9.61e-2)" "unprognostic (1.01e-2)" "unprognostic (3.89e-3)" "unprognostic (8.58e-2)" "unprognostic (6.12e-2)" "unprognostic (2.14e-3)" "unprognostic (2.19e-1)" "prognostic favorable (4.67e-11)" "unprognostic (6.25e-2)" "unprognostic (1.56e-1)" "unprognostic (2.58e-1)" "unprognostic (5.61e-2)" 6.6 9.0 6.6 2.6 10.3 6.0 6.4 8.6 7.6 8.9 10.7 7.6 3.3 8.6 3.2 5.8 7.5 1.9 19.3 5.8 8.1 12.7 9.6 8.5 2.1 8.0 6.9 9.5 14.4 7.7 14.4 6.3 7.9 8.2 1.7 2.8 10.1 4.1 8.9 6.3 6.7 1.9 5.2 8.6 9.2 9.2 7.5 1.6 8.9 2.4 1.4 7.3 6.3 6.3 3.7 7.4 5.7 8.2 5.5 2.9 12.5 5.9 4.8 4.3 3.1 14.9 7.0 2.1 6.0 4.2 7.0 6.2 3.4 5.8 2.4 1.6 7.9 2.9 7.8 10.4 4.2 4.7 12.5 4.0 4.3 3.9 1.9 4.7 5.2 3.9 5.1 7.0 3.6 5.9 3.1 18.4 4.9 5.1 7.8 4.3 4.2 7.1 4.8 8.6 5.6 4.6 7.4 3.0 8.1 3.4 6.7 8.6 5.6 5.1 4.7 4.1 8.2 4.2 2.9 2.8 5.9 13.3 7.2 21.9 23.2 60.1 9.3 19.7 8.1 9.9 8.6 8.8 13.3 10.0 9.4 8.6 20.5 11.7 19.1 10.2 11.5 27.3 6.6 10.3 8.6 7.6 5.8 8.1 8.0 6.9 7.9 5.2 7.5 6.3 95.0 109.0 90.9 21.2 78.0 67.8 174.6 267.7 52.9 70.6 75.3 84.2 165.9 108.7 158.7 195.0 45.9 584.3 75.8 147.7 50.9 159.3 40.4 85.5 229.6 88.2 82.6 35.7 22.5 107.9 184.0 152.5 79.0 71.2 81.1 102.3 62.4 92.6 243.1 38.7 20.6 121.6 164.8 100.5 80.2 60.0 126.2 154.2 147.7 16.9 107.1 140.0 91.6 28.1 16.7 95.4 153.4 151.6 205.2 124.5 204.6 273.7 144.8 86.2 78.9 82.8 108.1 272.5 161.4 40.7 61.4 693.5 86.0 99.9 109.9 140.5 LRRC59 "FLJ21675, PRO1855" ENSG00000108829 "Leucine rich repeat containing 59" Q96AG4 17 50375059-50397523 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 272.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030827, HPA030829" Enhanced Enhanced "Endoplasmic reticulum" NA NA 740000 "Cluster 52: Eosinophils - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "HPA030827: AB_10602704, HPA030829: AB_10670045" "unprognostic (4.73e-2)" "unprognostic (2.15e-2)" "prognostic favorable (2.60e-4)" "unprognostic (5.63e-3)" "unprognostic (2.80e-1)" "prognostic unfavorable (1.00e-5)" "prognostic unfavorable (3.12e-6)" "unprognostic (1.88e-3)" "unprognostic (9.95e-2)" "unprognostic (5.62e-3)" "prognostic unfavorable (6.87e-4)" "unprognostic (3.68e-2)" "prognostic unfavorable (1.19e-6)" "unprognostic (2.77e-1)" "unprognostic (1.44e-1)" "unprognostic (3.39e-3)" "prognostic unfavorable (1.90e-5)" 49.6 82.6 18.5 54.1 20.5 79.3 34.1 18.4 21.7 60.4 19.0 72.1 46.8 32.2 55.5 47.9 29.4 32.2 33.0 19.1 18.6 41.1 75.0 45.8 30.9 18.2 19.3 21.7 119.4 34.8 21.8 51.7 18.6 35.3 72.0 21.7 56.2 35.7 32.6 24.3 46.0 52.3 18.3 33.0 73.8 29.2 22.0 29.3 36.0 17.0 42.8 56.6 30.1 19.9 390.5 289.9 81.8 123.6 135.3 158.7 146.2 310.7 172.3 284.5 249.4 668.8 109.0 168.8 207.8 356.4 174.3 138.1 205.2 265.2 336.3 90.4 298.6 295.9 154.8 361.8 283.7 294.1 134.8 140.8 211.3 305.2 351.7 82.6 213.3 95.7 278.9 155.6 189.4 264.3 209.0 139.0 92.5 364.2 419.1 175.9 261.9 323.6 156.0 194.9 199.1 165.4 107.5 119.3 161.9 120.4 201.1 157.9 229.6 327.4 135.5 306.2 410.4 232.3 205.1 213.6 222.2 195.9 210.8 22.8 21.9 19.8 9.4 26.9 11.7 11.0 9.5 11.5 20.3 8.5 6.1 7.9 10.9 8.6 27.8 16.5 10.3 13.0 18.5 20.5 18.4 21.7 19.1 18.6 18.2 19.3 18.6 18.3 22.0 19.9 33.1 22.4 23.7 5.2 61.2 139.4 102.1 54.7 43.9 20.4 55.0 30.9 4.1 40.0 50.0 20.2 2.1 90.8 38.4 101.6 29.4 165.0 67.1 53.6 53.8 45.6 38.3 36.6 5.5 187.0 272.2 64.5 104.5 96.3 30.4 28.9 27.1 69.1 103.3 21.9 5.5 178.3 26.4 29.0 111.1 18.7 35.4 45.1 65.8 3.7 45.6 26.5 30.9 2.0 6.8 187.7 75.7 29.0 211.3 164.8 63.5 48.0 26.5 15.5 13.1 59.1 92.8 61.3 27.7 66.1 132.7 236.0 33.2 38.3 127.1 146.7 LRRN2 "FIGLER7, GAC1, LRANK1, LRRN5" ENSG00000170382 "Leucine rich repeat neuronal 2" O75325 1 204617170-204685738 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 22.2;Distal enterocytes: 18.1;Excitatory neurons: 57.8;Horizontal cells: 52.2;Inhibitory neurons: 40.0;Oligodendrocyte precursor cells: 39.2" "Group enriched" "Detected in many" 6 "breast cancer: 6.1;endometrial cancer: 10.6;glioma: 16.8;ovarian cancer: 18.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 9.3;NTERA-2: 18.0;RPMI-8226: 29.0;SuSa: 9.8;T-47d: 10.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029124 Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Endoplasmic reticulum" "HPA029124: AB_10601545" "unprognostic (2.16e-2)" "unprognostic (1.93e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (2.59e-7)" "unprognostic (1.40e-1)" "unprognostic (1.17e-1)" "unprognostic (2.89e-2)" "unprognostic (1.21e-1)" "unprognostic (4.63e-2)" "unprognostic (1.15e-1)" "unprognostic (1.52e-3)" "unprognostic (1.16e-2)" "unprognostic (1.68e-2)" "unprognostic (1.43e-2)" "unprognostic (7.33e-2)" "unprognostic (1.88e-1)" "unprognostic (1.59e-3)" 6.1 4.4 18.4 2.8 18.6 1.7 2.5 6.9 19.6 3.3 20.4 8.0 1.1 5.5 0.3 1.8 7.6 4.3 8.2 20.5 18.5 17.4 1.0 2.8 2.1 11.0 13.6 2.5 1.9 14.7 12.9 0.7 13.8 1.5 5.3 3.8 3.0 2.2 1.6 0.4 4.9 7.2 7.7 7.6 2.0 4.2 20.2 3.0 3.1 3.2 0.7 1.4 2.2 13.2 0.0 4.3 3.5 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.3 0.0 0.1 0.4 0.0 0.0 0.0 0.2 0.2 9.3 0.6 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.9 1.5 0.0 18.0 0.0 0.1 0.2 0.0 29.0 0.0 0.2 2.4 0.4 5.6 0.1 0.0 9.8 10.1 0.0 0.0 0.0 3.9 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.4 18.6 6.9 19.6 20.5 18.5 11.0 13.6 13.8 7.7 20.2 13.2 3.9 0.0 0.0 22.2 0.3 0.4 0.7 0.1 0.0 7.0 0.6 1.9 1.5 0.0 0.1 1.8 2.1 0.1 0.0 18.1 0.0 3.8 0.0 0.5 0.2 2.3 11.4 2.7 57.8 0.9 0.1 2.9 0.0 0.8 0.0 0.1 3.3 0.0 7.0 52.2 40.0 2.3 2.0 0.3 1.1 0.5 0.0 0.2 0.0 9.4 0.2 4.6 0.0 39.2 1.6 4.9 5.6 0.0 0.1 0.3 0.0 5.5 0.0 1.1 0.0 0.9 0.5 0.1 0.3 0.5 0.1 0.4 0.2 1.4 1.0 0.4 MANF "ARMET, ARP" ENSG00000145050 "Mesencephalic astrocyte derived neurotrophic factor" P55145 3 51385291-51389397 "Plasma proteins, Predicted secreted proteins" "Stress response, Unfolded protein response" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 426.1;Syncytiotrophoblasts: 459.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 109.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011175 Approved Supported "Endoplasmic reticulum" "Secreted to blood" NA NA 7500000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "HPA011175: AB_1845039" "unprognostic (2.90e-2)" "unprognostic (5.24e-2)" "unprognostic (1.11e-2)" "unprognostic (2.51e-2)" "unprognostic (5.84e-2)" "prognostic unfavorable (9.58e-6)" "prognostic unfavorable (7.48e-4)" "unprognostic (7.37e-2)" "unprognostic (1.25e-1)" "unprognostic (1.12e-3)" "unprognostic (1.35e-1)" "unprognostic (3.01e-1)" "unprognostic (1.21e-2)" "unprognostic (1.46e-1)" "unprognostic (1.99e-2)" "unprognostic (1.27e-1)" "unprognostic (5.10e-2)" 39.4 36.7 34.4 70.9 34.5 35.3 41.8 37.8 50.5 59.4 44.2 55.4 42.5 48.2 169.3 53.2 42.8 32.1 51.1 34.8 42.7 48.6 109.2 44.3 50.5 38.4 35.7 28.7 81.1 38.8 56.4 59.9 37.2 51.3 58.8 17.7 51.0 50.5 12.4 36.6 39.5 47.2 36.2 56.1 59.5 43.2 37.9 47.7 117.8 20.8 76.1 67.8 35.5 38.1 128.6 61.2 164.7 207.7 107.8 139.4 173.8 200.2 160.6 194.0 184.5 99.6 292.6 271.6 162.6 121.9 449.8 77.7 201.4 200.0 187.3 128.9 92.2 220.2 93.5 230.3 349.8 108.2 137.1 60.6 168.5 201.3 271.7 189.9 252.7 112.3 48.3 299.5 181.6 75.5 184.8 215.6 144.6 298.0 237.6 76.4 105.3 288.7 162.8 86.9 64.4 201.6 165.3 104.2 130.3 175.8 83.7 141.2 129.3 117.4 112.1 140.4 222.6 247.9 105.0 186.5 195.4 217.5 221.2 73.2 15.3 9.4 28.8 13.0 35.5 17.4 20.2 27.5 16.0 12.1 14.9 16.0 8.5 26.0 8.3 109.8 13.4 16.9 34.4 34.5 37.8 50.5 34.8 42.7 38.4 35.7 37.2 36.2 37.9 38.1 55.9 32.1 21.5 5.2 134.1 163.1 223.7 232.5 31.3 15.1 50.5 40.5 69.3 61.5 104.0 55.2 6.2 188.1 142.8 75.7 43.0 172.6 99.0 73.3 101.9 88.3 116.6 26.1 5.8 124.6 387.0 101.2 71.9 99.4 62.9 77.9 79.6 156.1 179.5 11.8 8.5 235.9 118.0 36.1 170.6 123.3 60.0 63.0 181.5 7.5 79.1 39.6 117.4 5.0 9.5 167.8 90.5 51.6 426.1 245.0 47.7 78.9 71.1 19.1 65.7 59.7 194.2 176.8 91.1 42.8 160.5 459.0 94.8 40.6 120.9 202.0 MARCHF6 "MARCH-VI, MARCH6, RNF176, TEB4" ENSG00000145495 "Membrane associated ring-CH-type finger 6" O60337 5 10353695-10440388 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase Epilepsy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 38.5;Cardiomyocytes: 102.5;Cytotrophoblasts: 54.4;dendritic cells: 25.8;Extravillous trophoblasts: 30.0;Hofbauer cells: 36.4;Syncytiotrophoblasts: 81.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040841, HPA063246" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 20: HeLa - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" "Endoplasmic reticulum" "HPA040841: AB_2677162, HPA063246: AB_2684970" "unprognostic (3.31e-2)" "unprognostic (2.04e-1)" "unprognostic (2.85e-2)" "unprognostic (3.80e-3)" "unprognostic (4.00e-1)" "unprognostic (2.26e-1)" "unprognostic (3.06e-2)" "unprognostic (9.52e-3)" "unprognostic (1.53e-1)" "unprognostic (1.05e-3)" "unprognostic (3.94e-2)" "unprognostic (5.58e-2)" "unprognostic (5.08e-3)" "unprognostic (1.61e-1)" "unprognostic (2.88e-1)" "unprognostic (3.57e-1)" "unprognostic (8.50e-3)" 22.1 25.5 16.1 20.3 23.7 76.5 25.9 28.3 20.7 20.1 2.9 26.9 32.8 22.7 25.5 20.9 24.9 24.5 30.8 22.0 30.4 34.1 32.5 25.1 24.7 13.7 17.5 36.0 39.3 62.4 20.8 22.8 16.9 22.7 19.8 36.6 25.6 23.8 48.4 24.8 30.3 18.9 13.8 28.2 30.2 29.9 27.9 32.3 29.3 51.8 23.3 23.7 18.6 33.5 37.4 55.1 90.1 69.9 50.6 40.4 73.7 57.7 53.7 48.9 61.8 52.8 97.0 39.4 85.4 54.4 67.2 52.3 48.2 37.7 65.4 82.9 43.0 50.7 179.7 36.2 35.6 61.4 54.6 47.4 40.6 49.0 53.1 50.0 45.8 41.4 62.1 85.1 45.0 42.4 33.1 47.2 32.8 29.9 38.5 50.9 37.6 57.0 38.0 72.4 38.7 56.0 107.2 57.9 38.4 41.3 48.2 32.5 44.8 58.4 56.8 29.1 43.7 59.3 94.1 55.7 43.1 40.7 42.8 15.6 7.4 12.6 11.2 8.4 12.8 11.7 10.8 11.0 6.3 9.6 12.5 12.4 12.1 9.1 11.1 5.0 10.4 9.1 16.1 23.7 28.3 20.7 22.0 30.4 13.7 17.5 16.9 13.8 27.9 33.5 38.5 0.0 0.0 0.0 13.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 102.5 0.0 0.0 0.0 0.0 54.4 25.8 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 30.0 19.3 0.0 0.0 0.0 0.0 0.0 0.0 36.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.0 0.0 0.0 0.0 0.0 81.3 5.8 0.0 0.0 0.0 MFAP4 ENSG00000166482 "Microfibril associated protein 4" P55083 17 19383442-19387190 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Fibroblasts: 903.5;Peritubular cells: 240.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 11 "eosinophil: 1.0;intermediate monocyte: 1.8;non-classical monocyte: 1.9" "Group enriched" "Detected in many" 15 "granulocytes: 1.0;monocytes: 1.9" "Cell line enhanced" "Detected in many" "ASC diff: 394.8;ASC TERT1: 597.9;fHDF/TERT166: 284.0;HHSteC: 275.4;HSkMC: 417.8;MOLT-4: 375.8;SH-SY5Y: 350.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA054097 Supported Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 110000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA054097: AB_2682378" "unprognostic (3.02e-2)" "unprognostic (9.07e-2)" "unprognostic (3.39e-1)" "unprognostic (8.56e-3)" "unprognostic (9.80e-2)" "prognostic favorable (3.51e-4)" "unprognostic (2.20e-2)" "unprognostic (1.19e-1)" "unprognostic (3.87e-2)" "prognostic unfavorable (4.64e-4)" "unprognostic (1.37e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (6.83e-7)" "unprognostic (1.07e-2)" "unprognostic (2.92e-2)" "unprognostic (3.50e-2)" "prognostic unfavorable (7.12e-4)" 271.8 81.9 6.5 74.0 10.0 2.7 197.7 7.0 9.5 326.1 13.1 287.5 102.0 237.3 289.0 293.2 227.5 646.2 273.2 6.1 8.3 61.4 45.6 634.7 65.7 7.7 9.0 325.8 71.3 7.0 87.5 156.7 6.6 226.7 139.1 17.3 108.1 129.8 41.6 144.7 187.6 262.7 6.9 59.8 176.1 31.8 8.1 42.4 114.5 249.7 78.6 488.8 244.6 6.9 0.3 0.7 0.6 0.1 394.8 597.9 0.8 44.8 160.0 4.6 3.2 0.2 0.0 0.2 0.1 284.0 0.1 0.2 0.1 0.0 0.8 0.3 1.2 0.0 0.3 0.0 275.4 14.4 0.2 417.8 0.0 2.6 0.1 4.7 0.0 3.9 0.1 0.0 0.4 0.0 375.8 33.8 7.1 0.1 0.4 26.4 24.9 0.7 0.0 0.2 35.8 350.2 0.4 0.2 0.3 2.4 0.4 82.4 0.2 50.9 3.3 2.3 0.1 0.4 0.5 0.1 48.9 15.4 0.1 0.0 0.1 1.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 6.5 10.0 7.0 9.5 6.1 8.3 7.7 9.0 6.6 6.9 8.1 6.9 35.1 3.2 12.1 0.0 0.3 47.5 0.7 0.2 5.7 0.7 2.3 4.2 10.7 0.0 3.1 1.8 0.0 7.2 1.3 0.0 0.0 0.2 0.7 0.3 21.4 15.9 0.0 0.0 0.0 0.0 3.6 903.5 6.1 0.4 1.3 0.1 15.4 0.2 9.4 0.0 0.0 0.0 0.0 0.0 62.9 6.3 78.3 3.9 67.6 14.0 0.0 80.2 0.0 0.5 0.1 0.1 0.0 240.0 2.6 2.2 0.0 0.0 2.9 3.3 19.7 38.6 103.1 0.4 0.5 8.8 41.1 19.4 6.9 0.2 0.0 2.2 MIA2 "cTAGE-5A, cTAGE-5B, cTAGE-5C, cTAGE-5D, CTAGE5, FLJ22404, MEA6, MGEA, MGEA11, MGEA6, TALI" ENSG00000150527 "MIA SH3 domain ER export factor 2" Q96PC5 14 39230231-39388513 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 138.9" "Cell type enhanced" "Detected in many" "Collecting duct cells: 44.1;Ductal cells: 42.9;Endometrial ciliated cells: 78.7;Exocrine glandular cells: 42.7;Glandular and luminal cells: 93.5;Pancreatic endocrine cells: 41.3;Proximal tubular cells: 61.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CAPAN-2: 125.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000387, HPA000922, HPA054066, HPA055459" Approved Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 7: Non-specific - Mitochondria" "Endoplasmic reticulum" "HPA000387: AB_1078582, HPA000922: AB_1078581, HPA054066: AB_2682368, HPA055459: AB_2682819" "unprognostic (2.62e-1)" "unprognostic (7.17e-3)" "unprognostic (2.33e-1)" "unprognostic (5.27e-4)" "unprognostic (3.21e-4)" "unprognostic (2.63e-1)" "unprognostic (2.48e-1)" "unprognostic (7.18e-2)" "unprognostic (1.12e-1)" "unprognostic (1.21e-2)" "unprognostic (4.31e-2)" "unprognostic (1.78e-1)" "prognostic favorable (2.81e-4)" "unprognostic (6.93e-2)" "unprognostic (8.08e-2)" "unprognostic (2.91e-1)" "unprognostic (3.97e-2)" 12.1 26.6 5.6 16.8 6.9 23.6 22.1 5.8 7.9 29.7 58.0 30.8 80.4 15.7 40.2 26.9 22.2 30.3 16.6 9.4 6.5 78.4 138.9 15.5 16.2 5.6 4.7 9.6 43.6 40.5 15.5 11.2 6.4 21.1 34.6 12.8 52.5 19.2 54.5 9.9 78.4 12.3 4.1 14.5 45.3 21.0 5.1 14.3 46.7 20.7 19.8 16.2 17.2 7.1 23.0 25.1 10.4 18.5 20.6 23.2 14.5 13.3 13.9 9.3 9.6 19.7 125.4 27.5 40.1 15.0 18.9 34.1 12.7 15.0 11.0 21.4 10.6 17.2 11.5 106.1 48.2 23.2 30.7 14.4 83.7 9.2 69.2 59.0 15.3 31.8 16.6 68.3 14.0 22.1 14.9 18.9 12.0 87.2 20.8 15.2 18.3 34.9 42.7 24.7 8.7 5.1 31.0 32.5 20.4 13.1 31.2 24.8 24.3 14.1 9.2 10.4 8.8 38.7 35.7 27.2 7.9 14.5 12.0 40.9 16.3 25.9 15.4 18.0 14.0 11.7 11.6 14.4 17.8 13.1 14.2 13.2 34.5 14.6 21.0 12.3 11.8 11.8 5.6 6.9 5.8 7.9 9.4 6.5 5.6 4.7 6.4 4.1 5.1 7.1 26.7 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.0 33.1 19.9 0.0 5.7 0.0 44.1 0.0 5.6 35.9 0.8 7.9 42.9 0.5 78.7 30.7 7.1 0.0 0.0 0.1 42.7 5.0 4.6 0.0 93.5 0.0 10.3 0.0 3.8 7.6 0.0 0.1 1.8 0.0 0.0 0.0 0.6 0.0 12.7 0.0 0.0 23.8 0.0 1.0 0.0 0.0 41.3 0.0 0.0 8.1 0.0 6.6 61.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 7.0 13.6 20.0 0.2 0.0 MMRN1 "ECM, EMILIN4, GPIa*, MMRN" ENSG00000138722 "Multimerin 1" Q13201 4 89879532-89954629 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Endothelial cells: 158.0;Hepatic stellate cells: 146.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 9 "NK-cell: 6.3;plasmacytoid DC: 2.2" "Group enriched" "Detected in many" 9 "dendritic cells: 2.2;NK-cells: 6.3" "Cell line enriched" "Detected in some" 13 "HUVEC TERT2: 1242.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA035769 Enhanced Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 200000000 "Cluster 48: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "HPA035769: AB_10696511" "unprognostic (1.15e-1)" "unprognostic (1.81e-2)" "unprognostic (1.23e-1)" "unprognostic (2.41e-1)" "unprognostic (2.11e-1)" "unprognostic (7.05e-3)" "unprognostic (1.62e-3)" "unprognostic (1.91e-1)" "unprognostic (1.88e-1)" "unprognostic (2.12e-1)" "unprognostic (9.71e-3)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.77e-4)" "prognostic unfavorable (5.46e-4)" "unprognostic (2.14e-1)" "unprognostic (1.36e-1)" "unprognostic (2.23e-2)" 22.6 3.8 0.8 10.9 0.8 1.8 27.3 0.8 1.1 28.5 1.4 9.9 5.4 15.0 2.8 14.5 23.1 21.1 3.6 0.6 0.9 1.1 8.7 16.1 14.0 1.4 1.4 4.9 3.4 0.5 0.7 40.1 1.2 3.8 14.9 0.5 2.7 4.6 1.1 8.2 13.5 16.8 1.1 0.6 5.2 12.7 1.5 3.7 23.1 6.6 7.6 19.6 9.8 1.1 0.0 0.0 94.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.2 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 1242.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 43.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.0 0.0 6.3 0.0 2.2 0.2 1.2 0.8 0.8 0.8 1.1 0.6 0.9 1.4 1.4 1.2 1.1 1.5 1.1 15.4 0.0 12.0 0.3 2.3 4.2 0.1 0.0 0.0 0.0 0.7 0.1 2.2 0.0 0.6 0.0 0.0 0.0 3.9 0.0 1.9 0.0 17.7 0.3 0.7 158.0 0.0 25.9 0.2 0.0 0.0 1.9 0.0 0.4 2.5 0.1 146.3 2.4 0.6 0.0 0.1 0.0 0.0 5.7 5.9 7.7 0.3 9.1 1.8 21.5 0.7 0.8 2.1 0.0 0.4 0.0 0.0 0.0 5.0 0.4 0.0 0.0 1.5 0.4 0.0 0.3 0.9 15.4 0.0 0.8 4.5 0.0 1.6 0.0 0.0 0.1 MOGS "CWH41, DER7, GCS1" ENSG00000115275 "Mannosyl-oligosaccharide glucosidase" Q13724 2 74461057-74465410 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 222.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011322, HPA011969" Approved Supported "Endoplasmic reticulum" NA NA 1500000 "Cluster 41: Basophils - Cellular respiration" "Cluster 29: Non-specific - Vesicular transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" "Endoplasmic reticulum" "HPA011322: AB_2668483, HPA011969: AB_1849579" "unprognostic (5.66e-2)" "unprognostic (1.98e-2)" "prognostic unfavorable (5.33e-4)" "unprognostic (1.91e-2)" "unprognostic (4.67e-2)" "unprognostic (2.04e-1)" "prognostic unfavorable (2.34e-6)" "unprognostic (1.48e-2)" "unprognostic (2.66e-2)" "unprognostic (3.32e-2)" "unprognostic (6.21e-2)" "unprognostic (4.36e-1)" "prognostic unfavorable (2.79e-8)" "unprognostic (1.40e-2)" "unprognostic (3.06e-2)" "unprognostic (2.66e-1)" "unprognostic (7.59e-3)" 18.4 18.3 8.1 20.2 9.1 8.5 18.6 9.0 13.3 19.2 9.2 22.8 41.7 18.3 5.5 22.5 20.0 14.4 16.9 8.3 9.0 20.9 34.3 24.9 21.6 9.4 8.7 18.6 42.3 21.5 21.7 34.5 9.9 23.3 13.4 9.6 31.1 14.6 21.3 24.9 29.7 11.4 9.3 31.7 35.5 19.0 8.9 19.8 21.9 16.2 18.1 20.1 19.1 9.8 53.1 46.2 23.5 29.6 55.3 38.9 90.1 38.7 58.3 59.8 58.2 81.9 58.7 45.2 34.9 36.3 46.7 50.6 40.2 43.3 32.5 46.7 39.9 20.3 14.4 68.6 54.9 49.8 46.6 25.6 77.1 41.9 39.0 62.2 68.4 27.8 39.6 51.6 28.5 58.8 32.3 62.0 42.6 64.1 22.5 35.5 57.4 74.1 38.0 19.5 19.7 29.2 15.5 84.8 62.7 21.8 38.7 34.3 40.1 26.5 49.7 36.3 56.5 66.5 36.5 22.7 46.9 49.3 39.0 6.7 2.4 1.9 2.6 1.5 3.3 1.2 2.3 2.5 2.1 1.9 1.4 1.6 0.4 8.4 3.3 2.1 3.3 1.7 8.1 9.1 9.0 13.3 8.3 9.0 9.4 8.7 9.9 9.3 8.9 9.8 13.9 6.4 15.9 16.3 22.0 15.8 21.8 20.8 18.2 14.9 18.9 12.8 8.6 24.3 21.3 23.9 18.8 39.5 34.6 18.7 5.9 21.9 65.6 12.4 12.2 13.3 13.9 16.4 13.9 26.1 50.5 12.3 40.8 17.4 4.5 20.9 17.9 25.6 19.9 6.7 12.1 25.7 20.3 12.9 14.8 222.0 15.2 17.9 10.6 12.2 25.5 7.0 30.9 11.1 10.7 22.3 19.7 7.2 43.6 22.7 37.7 7.4 17.7 14.1 13.1 9.4 12.7 13.0 5.1 15.2 17.3 52.0 21.2 16.5 23.3 19.6 MOK "RAGE, RAGE1, STK30" ENSG00000080823 "MOK protein kinase" Q9UQ07 14 102224500-102305190 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 125.8;testis: 54.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 185.6;Early spermatids: 212.8;Late spermatids: 185.8;Respiratory ciliated cells: 156.9;Rod photoreceptor cells: 465.7" "Cancer enriched" "Detected in many" 4 "melanoma: 7.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 8.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HBF TERT88: 149.0;hTEC/SVTERT24-B: 383.5;NB-4: 499.1;U-138 MG: 200.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027292 Supported "Endoplasmic reticulum" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 24: NB-4 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Endoplasmic reticulum" "HPA027292: AB_10600989" "unprognostic (8.16e-2)" "unprognostic (1.82e-1)" "unprognostic (6.68e-2)" "unprognostic (6.05e-3)" "unprognostic (1.34e-2)" "unprognostic (1.81e-2)" "unprognostic (4.43e-2)" "unprognostic (3.49e-4)" "unprognostic (2.19e-1)" "unprognostic (2.03e-2)" "unprognostic (2.93e-1)" "unprognostic (3.01e-3)" "unprognostic (5.97e-2)" "unprognostic (1.81e-1)" "unprognostic (2.17e-1)" "unprognostic (1.26e-2)" "unprognostic (2.48e-1)" 9.2 11.2 15.7 1.8 16.0 3.0 6.8 14.8 18.6 8.9 26.9 5.3 3.4 7.8 7.3 4.3 21.2 4.6 13.0 17.2 16.9 12.6 5.8 5.3 1.7 16.2 17.2 12.9 9.7 7.1 18.6 2.4 15.9 7.6 1.8 125.8 6.3 3.5 2.2 6.8 3.0 3.9 15.0 4.7 9.3 54.0 17.1 1.7 14.8 0.7 1.3 8.4 5.5 15.6 18.9 16.5 2.2 9.5 3.8 13.1 4.2 37.7 11.0 53.4 63.7 1.5 45.4 14.5 3.1 7.2 11.5 4.1 3.3 19.4 149.0 16.2 14.1 3.4 2.3 12.7 15.9 1.6 17.9 11.1 4.9 383.5 35.3 41.3 2.0 2.9 3.4 1.0 35.3 12.5 1.2 499.1 0.7 8.3 39.4 2.2 1.0 0.3 21.9 0.8 6.0 3.9 6.8 2.6 109.4 0.8 11.2 1.5 1.4 200.4 10.4 7.7 12.1 1.3 2.4 1.2 40.2 1.2 93.1 0.0 0.7 0.0 0.5 0.6 0.8 0.0 0.4 1.4 3.0 0.5 0.7 1.7 0.5 8.0 0.1 0.0 0.0 0.9 15.7 16.0 14.8 18.6 17.2 16.9 16.2 17.2 15.9 15.0 17.1 15.6 5.8 19.2 17.5 68.6 1.0 10.7 6.3 12.0 7.4 40.9 19.1 17.3 12.3 10.0 27.5 12.9 185.6 1.4 2.4 6.1 5.9 8.3 212.8 122.1 16.9 7.2 4.8 3.6 54.7 16.0 2.6 17.6 12.2 10.7 3.8 12.2 8.6 2.0 2.1 16.8 37.5 2.4 6.1 1.3 5.3 185.8 30.4 2.5 80.0 7.5 0.5 59.5 1.0 16.1 6.8 6.5 1.2 16.1 1.1 2.7 3.5 11.1 156.9 465.7 26.3 22.4 13.4 121.4 32.0 5.4 5.8 1.2 4.2 13.4 4.2 3.8 MOSPD2 MGC26706 ENSG00000130150 "Motile sperm domain containing 2" Q8NHP6 X 14873421-14922327 "Predicted intracellular proteins, Predicted membrane proteins" Chemotaxis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 48.9" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 125.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 53.4" "Group enriched" "Detected in all" 6 "granulocytes: 53.4;monocytes: 15.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003334 Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 18: U-2197 - ECM organization" "Cluster 10: Non-specific - Unknown function" "Endoplasmic reticulum" "HPA003334: AB_2146004" "unprognostic (2.74e-1)" "unprognostic (4.39e-2)" "unprognostic (6.52e-2)" "unprognostic (2.29e-1)" "unprognostic (7.57e-2)" "unprognostic (6.39e-2)" "prognostic unfavorable (8.91e-4)" "unprognostic (1.51e-1)" "unprognostic (7.24e-2)" "unprognostic (4.21e-3)" "unprognostic (1.00e-1)" "unprognostic (8.64e-2)" "unprognostic (1.04e-1)" "unprognostic (4.56e-1)" "unprognostic (1.37e-1)" "unprognostic (2.69e-1)" "unprognostic (1.96e-2)" 8.3 6.9 9.8 10.7 19.8 8.1 8.5 17.2 21.3 10.7 1.3 6.7 8.2 8.9 7.4 13.1 6.8 11.5 5.1 10.0 12.0 8.6 9.5 14.2 11.6 25.9 15.8 10.5 5.4 6.5 3.6 15.4 24.8 7.1 7.2 7.3 6.6 6.9 2.4 19.4 7.7 8.6 15.7 14.0 8.0 4.0 19.0 8.7 15.0 4.5 9.9 8.6 8.0 48.9 9.4 13.4 9.6 4.9 33.1 20.8 9.4 22.8 21.4 16.2 19.2 7.0 11.1 13.0 6.1 39.0 25.0 15.4 12.6 9.8 20.7 9.0 11.1 4.5 12.5 5.5 20.4 8.6 10.0 19.0 13.5 14.4 19.0 15.6 14.4 12.7 5.8 12.5 15.3 4.5 7.9 7.0 6.6 8.7 12.0 8.2 12.7 10.6 13.2 6.2 3.0 6.9 17.1 7.8 38.5 36.8 6.6 12.7 14.9 13.9 5.6 48.9 8.8 7.6 9.7 8.1 18.3 6.6 20.3 11.8 14.7 6.6 2.7 14.4 3.3 2.1 3.0 2.2 5.1 3.1 3.2 3.4 53.4 5.4 15.8 1.6 3.6 5.8 9.8 19.8 17.2 21.3 10.0 12.0 25.9 15.8 24.8 15.7 19.0 48.9 18.3 22.4 18.2 16.3 15.5 8.5 7.3 5.7 14.8 7.3 10.2 8.3 6.0 11.5 10.9 22.0 6.2 15.5 12.6 9.1 9.8 7.0 5.8 20.3 10.6 14.4 12.6 6.7 17.2 6.1 9.4 14.3 12.2 16.6 7.6 8.7 18.9 8.2 21.8 6.7 17.2 6.7 10.2 28.9 7.1 24.3 10.5 32.7 10.6 23.4 32.5 8.0 8.2 14.1 125.8 6.9 5.7 15.1 12.6 6.7 7.8 11.4 15.4 4.7 13.1 11.6 13.4 9.9 7.9 16.8 12.8 23.5 10.3 11.4 6.4 6.7 MSMO1 "DESP4, ERG25, SC4MOL" ENSG00000052802 "Methylsterol monooxygenase 1" Q15800 4 165327667-165343164 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 575.6" "Cell type enhanced" "Detected in all" "Hepatocytes: 532.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "GAMG: 416.2;Karpas-707: 412.3;RPTEC TERT1: 399.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055073, HPA056127" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "HPA055073: , HPA056127: AB_2683045" "unprognostic (5.76e-2)" "prognostic unfavorable (2.97e-4)" "unprognostic (3.35e-2)" "unprognostic (7.85e-2)" "unprognostic (1.74e-1)" "unprognostic (1.20e-2)" "unprognostic (7.14e-2)" "unprognostic (1.75e-2)" "unprognostic (3.52e-2)" "unprognostic (2.06e-1)" "unprognostic (3.22e-3)" "unprognostic (2.28e-1)" "prognostic favorable (9.21e-4)" "unprognostic (2.39e-1)" "unprognostic (1.56e-2)" "unprognostic (3.54e-1)" "unprognostic (1.40e-1)" 18.3 95.2 36.7 20.9 48.2 10.4 66.2 45.1 47.5 57.1 37.4 39.2 75.7 19.1 97.0 145.7 20.9 21.7 18.5 43.9 59.2 52.6 575.6 70.3 20.7 90.5 58.4 25.7 22.6 42.9 18.4 22.9 78.6 58.9 32.9 26.1 34.7 12.1 5.5 82.5 38.1 16.5 45.0 11.0 31.5 52.8 48.4 13.4 22.4 6.5 27.0 20.2 67.0 61.1 89.1 21.7 198.8 36.4 97.7 312.0 37.5 35.3 159.0 44.7 123.4 41.5 372.9 43.4 20.6 43.1 416.2 71.7 101.6 366.3 49.4 37.7 63.0 20.0 20.0 127.6 194.9 35.8 26.8 192.6 237.6 163.6 100.6 61.1 58.8 55.7 35.3 412.3 74.6 45.7 32.6 58.2 115.6 46.9 21.0 16.8 21.8 132.3 399.5 102.5 39.7 30.0 54.5 77.9 33.9 121.7 36.1 44.7 67.6 20.6 36.1 18.5 24.7 75.9 86.5 58.6 43.9 36.0 28.5 13.7 8.6 8.8 34.0 11.6 25.4 40.6 31.8 31.4 15.0 37.6 34.3 35.6 6.1 24.9 20.5 19.3 31.0 29.2 36.7 48.2 45.1 47.5 43.9 59.2 90.5 58.4 78.6 45.0 48.4 61.1 16.9 51.3 168.0 70.5 28.9 36.1 70.1 189.2 21.6 33.8 81.9 23.0 10.7 40.0 160.0 69.9 27.1 55.6 20.7 130.8 35.2 67.9 6.4 27.6 12.2 30.4 60.7 53.9 33.6 71.7 87.0 24.1 35.2 44.4 47.7 83.0 27.8 532.0 28.3 35.3 22.8 72.8 170.9 28.0 11.5 7.0 24.8 18.3 32.0 10.3 23.6 27.2 17.5 42.7 49.6 86.8 85.7 18.8 10.9 138.3 46.0 38.4 103.2 50.4 19.7 5.6 35.1 8.7 15.4 84.6 115.1 123.0 22.3 136.1 36.9 129.0 MTDH "3D3, AEG-1, LYRIC" ENSG00000147649 Metadherin Q86UE4 8 97644184-97730260 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010932, HPA015104, CAB068204, CAB068205" Supported Enhanced "Endoplasmic reticulum" NA NA 300000 "Cluster 26: Non-specific - Mitochondria" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "CAB068204: AB_2665655, CAB068205: AB_2665654, HPA010932: AB_1079422, HPA015104: AB_1854173" "unprognostic (1.01e-3)" "unprognostic (1.41e-2)" "unprognostic (2.05e-2)" "unprognostic (6.56e-2)" "unprognostic (2.08e-1)" "unprognostic (2.24e-2)" "unprognostic (4.08e-2)" "prognostic unfavorable (7.76e-4)" "unprognostic (1.25e-1)" "unprognostic (2.08e-1)" "prognostic unfavorable (5.36e-4)" "unprognostic (1.20e-1)" "prognostic unfavorable (3.82e-4)" "unprognostic (3.84e-3)" "unprognostic (3.88e-2)" "unprognostic (2.77e-1)" "unprognostic (1.40e-1)" 53.3 41.4 18.6 56.0 26.7 109.9 39.0 26.2 24.5 52.6 27.2 51.3 51.2 50.1 33.7 52.2 41.1 41.2 35.7 17.2 21.2 40.8 89.6 40.7 59.3 28.3 23.2 50.7 30.4 53.4 13.4 28.9 28.6 44.7 47.5 44.8 29.3 41.4 60.2 27.0 52.2 62.5 25.9 41.6 48.1 39.6 23.3 65.9 62.7 50.6 61.0 56.3 22.7 37.1 191.5 96.4 61.1 84.7 97.3 102.7 30.7 167.8 139.0 104.2 79.4 59.9 137.0 173.5 181.5 164.6 114.1 121.6 150.3 115.2 143.6 189.5 79.9 320.0 97.5 69.6 118.2 170.5 142.4 78.6 109.3 128.1 282.2 97.3 119.3 126.2 215.5 300.2 108.4 77.6 286.0 43.2 38.9 160.9 113.0 187.2 73.0 255.4 64.5 108.6 92.3 69.2 118.3 101.3 132.0 58.6 158.0 105.1 126.8 146.7 52.7 135.8 123.6 166.1 196.4 174.5 134.3 194.5 130.9 57.0 71.5 38.1 35.7 49.2 49.7 71.6 51.1 52.8 87.0 51.4 51.9 45.7 10.1 51.4 54.6 112.2 33.3 31.9 18.6 26.7 26.2 24.5 17.2 21.2 28.3 23.2 28.6 25.9 23.3 37.1 185.1 128.2 109.2 69.2 294.6 261.7 233.0 178.9 194.1 0.0 166.1 150.7 109.9 201.6 146.1 141.6 0.0 10.0 231.7 140.5 25.4 230.9 267.4 156.0 269.9 185.1 121.8 205.7 96.4 231.7 98.6 227.2 156.5 178.5 137.1 183.1 164.6 438.0 267.5 0.0 97.0 249.9 146.5 258.7 273.9 163.5 195.4 266.5 184.9 86.2 258.2 0.0 195.7 110.6 141.8 241.8 137.8 216.3 675.9 374.7 160.8 99.2 87.2 0.0 223.5 237.8 334.5 162.1 129.6 249.8 314.8 13.7 200.3 285.6 251.6 315.0 MXRA7 "FLJ46603, PS1TP1, TMAP1" ENSG00000182534 "Matrix remodeling associated 7" P84157 17 76672551-76711016 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 203.7;Muller glia cells: 365.7;Rod photoreceptor cells: 163.8;Theca cells: 218.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-87 MG: 663.8" "HPA044819, HPA075316" Uncertain Enhanced "Endoplasmic reticulum" "Secreted to blood" NA NA 100000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 5: Muller glia cells - Visual perception" "Endoplasmic reticulum" "HPA044819: AB_10964134, HPA075316: " "unprognostic (1.34e-1)" "unprognostic (2.00e-1)" "unprognostic (1.32e-1)" "unprognostic (2.92e-1)" "unprognostic (1.19e-1)" "unprognostic (3.16e-2)" "prognostic unfavorable (4.70e-4)" "unprognostic (3.38e-2)" "unprognostic (1.21e-1)" "unprognostic (1.51e-3)" "unprognostic (2.07e-2)" "unprognostic (8.33e-2)" "unprognostic (5.39e-3)" "unprognostic (4.67e-3)" "unprognostic (6.21e-2)" "unprognostic (4.63e-3)" "prognostic unfavorable (1.80e-5)" 189.2 244.3 111.9 53.4 175.1 13.5 133.5 114.5 136.5 149.4 263.7 310.7 37.5 268.3 208.8 157.0 181.0 103.6 526.4 123.4 118.4 83.0 29.9 124.9 31.8 130.3 122.7 185.4 90.3 235.7 48.8 102.8 125.3 154.3 76.1 514.6 62.0 314.8 68.8 73.0 89.4 284.4 122.1 149.7 124.0 115.7 115.4 44.6 272.1 75.9 33.3 250.5 123.1 120.4 19.1 56.1 82.4 155.3 424.0 384.4 41.0 263.8 212.8 188.8 182.8 75.1 2.9 0.5 116.8 368.0 196.8 75.7 92.5 146.5 306.4 1.4 91.7 48.7 39.2 126.8 258.4 22.9 5.9 241.1 171.2 219.3 178.7 421.8 282.0 12.3 35.2 1.2 440.8 5.3 2.9 15.9 26.5 30.0 156.7 43.2 322.2 16.5 153.1 4.8 28.8 207.3 78.5 1.0 152.6 231.6 51.5 29.3 348.5 422.7 90.1 174.3 282.6 24.5 4.9 1.4 663.8 9.9 62.5 1.3 2.8 0.5 4.0 0.8 3.1 2.3 2.1 4.5 2.1 0.4 1.3 2.9 1.1 5.4 0.3 2.4 0.5 3.4 111.9 175.1 114.5 136.5 123.4 118.4 130.3 122.7 125.3 122.1 115.4 120.4 128.3 16.0 14.6 8.5 2.0 10.3 27.0 15.0 13.6 142.0 9.4 42.5 117.3 2.8 10.3 31.3 95.9 1.4 62.6 1.3 1.9 25.5 3.5 48.7 203.7 56.1 6.7 0.8 19.3 4.1 8.1 97.2 2.0 63.9 2.5 64.7 52.5 4.2 3.5 111.0 27.9 7.5 10.2 5.0 13.3 12.4 101.2 7.4 14.2 10.3 1.3 365.7 6.2 15.1 8.9 6.5 0.3 143.3 11.0 21.2 1.6 8.1 10.2 163.8 13.1 132.1 83.6 2.3 10.7 6.0 8.8 0.8 19.7 218.5 1.5 21.1 MYLK2 "KMLC, MLCK2, skMLCK" ENSG00000101306 "Myosin light chain kinase 2" Q9H1R3 20 31819308-31834689 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "skeletal muscle: 732.0" "Cell type enriched" "Detected in some" 5 "Skeletal myocytes: 15.9" "Cancer enhanced" "Detected in some" "glioma: 1.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 4.1;RH-30: 10.5;RPMI-8226: 8.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA059704, HPA059890" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 25: RPMI-8226 - Immune response" "Cluster 37: Myocytes - Muscle contraction" "Endoplasmic reticulum" "HPA059704: AB_2684108, HPA059890: AB_2684153" "unprognostic (1.74e-2)" "unprognostic (1.87e-1)" "unprognostic (8.84e-2)" "unprognostic (5.27e-2)" "prognostic favorable (4.00e-4)" "unprognostic (5.58e-2)" "unprognostic (1.38e-7)" "unprognostic (2.29e-1)" "unprognostic (2.60e-3)" "unprognostic (1.99e-1)" "unprognostic (1.20e-1)" "unprognostic (4.73e-2)" "unprognostic (7.25e-11)" "unprognostic (2.01e-1)" "unprognostic (3.15e-1)" "unprognostic (2.60e-2)" "unprognostic (2.70e-2)" 0.1 0.0 0.6 0.1 0.6 0.4 0.1 0.6 0.7 0.0 0.5 0.2 0.0 0.1 0.1 4.7 0.1 0.0 0.3 0.6 0.6 0.0 0.0 0.1 0.0 0.6 0.7 0.1 5.5 0.0 0.1 0.0 0.7 1.1 0.0 0.0 2.4 0.0 732.0 0.6 0.1 0.1 0.6 0.3 0.2 0.2 0.7 0.2 0.2 60.3 0.0 0.0 0.0 0.6 0.3 0.0 0.7 0.6 0.0 0.0 0.4 0.1 0.0 0.3 0.0 0.2 0.2 0.5 0.3 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.6 0.3 0.0 0.0 0.5 0.1 0.0 0.0 0.3 0.0 1.3 0.8 0.5 0.1 4.1 0.1 0.6 0.5 0.3 0.5 0.0 0.3 0.6 10.5 8.8 0.0 0.1 0.5 0.5 2.7 0.1 0.0 0.1 0.1 0.1 2.1 0.2 0.7 0.4 2.4 0.0 0.8 0.2 0.1 2.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.6 0.7 0.6 0.6 0.6 0.7 0.7 0.6 0.7 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 1.2 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 2.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 NAT8 "ATase2, GLA, Hcml1, TSC501" ENSG00000144035 "N-acetyltransferase 8 (putative)" Q9UHE5 2 73640723-73642422 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "kidney: 732.4" "Cell type enriched" "Detected in some" 13 "Proximal tubular cells: 2565.5" "Cancer enriched" "Detected in some" 5 "renal cancer: 242.1" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 15 "Hep G2: 10.7" "Low region specificity" "Detected in all" "HPA067855, HPA074519" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Endoplasmic reticulum" "HPA067855: AB_2732774, HPA074519: AB_2686699" "unprognostic (4.51e-2)" "unprognostic (6.36e-2)" "unprognostic (1.95e-1)" "unprognostic (1.81e-1)" "unprognostic (1.98e-1)" "unprognostic (4.95e-3)" "unprognostic (2.46e-1)" "unprognostic (1.90e-2)" "unprognostic (9.42e-2)" "unprognostic (1.82e-1)" "unprognostic (2.13e-2)" "unprognostic (8.60e-2)" "unprognostic (1.37e-3)" "unprognostic (2.07e-2)" "unprognostic (4.11e-3)" "unprognostic (2.13e-2)" "unprognostic (8.36e-5)" 0.1 0.3 1.1 0.1 0.5 0.1 0.2 0.1 0.7 0.2 0.0 1.1 4.6 0.1 0.0 0.0 1.2 0.6 0.1 0.8 0.8 732.4 82.7 0.2 0.0 0.6 0.3 1.3 0.2 0.0 0.6 0.0 0.1 0.2 0.1 1.8 0.1 0.1 0.0 0.0 7.2 0.1 0.4 1.1 0.6 0.5 1.0 0.0 0.1 0.0 0.0 0.1 0.1 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 10.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.5 0.1 0.7 0.8 0.8 0.6 0.3 0.1 0.4 1.0 0.8 0.0 0.0 0.0 0.0 19.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.0 36.8 0.0 0.0 0.0 0.3 187.9 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 22.9 51.1 0.0 0.0 0.0 1.1 0.0 1.0 0.4 0.0 0.0 12.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 61.3 2565.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.6 0.0 0.6 0.1 NCEH1 "AADACL1, KIAA1363, NCEH" ENSG00000144959 "Neutral cholesterol ester hydrolase 1" Q6PIU2 3 172630249-172711218 "Predicted intracellular proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 83.2;Pancreatic endocrine cells: 72.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 287.7;LHCN-M2: 133.1;U-251 MG: 132.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026888, HPA043873" Enhanced Approved "Endoplasmic reticulum" "Intracellular and membrane" No No "Cluster 25: Monocytes - Inflammatory response" "Cluster 58: Brain - Synaptic function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Endoplasmic reticulum" "HPA026888: AB_10601557, HPA043873: " "unprognostic (3.19e-1)" "unprognostic (9.67e-2)" "unprognostic (5.74e-2)" "unprognostic (1.27e-1)" "unprognostic (6.88e-3)" "unprognostic (5.41e-2)" "unprognostic (3.29e-2)" "unprognostic (1.10e-1)" "unprognostic (1.22e-1)" "unprognostic (1.87e-2)" "prognostic unfavorable (8.25e-5)" "unprognostic (5.29e-2)" "unprognostic (2.96e-2)" "unprognostic (2.42e-1)" "unprognostic (4.43e-2)" "unprognostic (2.81e-2)" "unprognostic (2.28e-1)" 3.8 16.2 8.7 8.7 15.8 8.3 5.6 2.3 27.5 4.3 0.0 11.6 4.2 4.6 3.2 3.9 3.4 6.9 14.2 12.5 4.3 21.5 4.9 19.9 14.3 9.3 4.9 1.5 4.7 8.0 3.2 6.7 9.6 6.7 12.0 19.6 10.3 4.4 6.1 1.4 4.8 3.4 3.5 11.2 12.8 1.6 7.8 4.9 4.5 7.4 11.2 8.5 2.1 6.9 98.1 55.3 1.9 3.0 3.3 3.4 7.8 71.8 47.5 46.5 27.2 14.0 287.7 8.1 105.4 43.4 44.4 19.2 2.0 35.1 107.0 27.1 4.5 5.6 8.5 10.8 3.9 14.8 19.9 1.7 3.5 32.3 47.5 43.6 31.5 4.4 1.4 6.9 133.1 8.0 2.5 5.1 2.6 27.4 43.5 2.3 5.2 10.0 83.0 12.6 1.6 0.8 43.6 45.2 9.6 3.1 15.4 6.8 86.9 71.3 10.7 34.1 132.0 8.2 16.4 6.8 53.3 14.1 55.4 6.8 17.9 0.7 2.6 11.6 1.7 3.3 1.6 1.9 12.8 2.2 1.6 2.0 0.6 3.4 7.8 0.7 1.7 6.4 8.7 15.8 2.3 27.5 12.5 4.3 9.3 4.9 9.6 3.5 7.8 6.9 6.6 48.1 17.9 35.9 6.6 6.8 18.3 5.2 1.8 14.8 11.5 3.7 31.6 22.8 20.1 16.5 22.9 9.0 4.7 43.0 3.9 64.1 7.5 41.2 6.4 8.5 7.8 50.5 83.2 31.0 5.2 6.6 25.0 64.1 5.1 5.5 6.8 2.4 49.7 5.0 68.2 11.5 4.1 42.8 15.2 4.1 0.9 32.8 5.4 22.5 12.2 5.4 3.1 15.6 5.4 72.9 13.0 2.6 2.9 30.6 7.3 24.6 27.4 20.5 6.6 8.6 7.0 0.0 1.1 4.3 3.4 10.5 4.6 9.3 7.8 27.3 NCR1 "CD335, LY94, NK-p46, NKP46" ENSG00000189430 "Natural cytotoxicity triggering receptor 1" O76036 19 54906148-54916140 "CD markers, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 3.5" "Group enriched" "Detected in some" 7 "dendritic cells: 30.2;NK-cells: 110.2" "Cancer enhanced" "Detected in single" "testis cancer: 1.2" "Region enriched" "Detected in single" 7 "cerebral cortex: 1.0" "Immune cell enriched" "Detected in single" 4 "NK-cell: 1.1" "Lineage enriched" "Detected in single" 4 "NK-cells: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA049311 Approved "Endoplasmic reticulum" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Endoplasmic reticulum" "HPA049311: AB_2680707" "unprognostic (3.92e-2)" "unprognostic (2.21e-3)" "unprognostic (1.67e-1)" "unprognostic (2.87e-4)" "unprognostic (2.89e-1)" "unprognostic (6.32e-4)" "unprognostic (2.22e-2)" "unprognostic (3.29e-1)" "unprognostic (1.07e-1)" "unprognostic (1.89e-2)" "unprognostic (1.45e-1)" "unprognostic (1.36e-1)" "unprognostic (1.15e-5)" "unprognostic (1.82e-2)" "unprognostic (5.92e-2)" "unprognostic (3.81e-3)" "unprognostic (6.05e-3)" 0.2 0.0 0.1 0.2 0.0 0.7 0.1 0.1 1.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.1 0.5 0.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.5 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 1.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 1.5 0.0 0.0 0.0 0.0 30.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 6.6 0.4 0.0 0.0 0.1 1.1 0.1 0.0 0.1 0.7 0.1 0.1 0.0 0.3 0.0 0.0 0.6 0.3 0.0 0.0 1.8 0.0 1.9 0.1 0.0 110.2 0.5 0.4 0.0 0.0 0.0 4.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.1 NECAP2 FLJ10420 ENSG00000157191 "NECAP endocytosis associated 2" Q9NVZ3 1 16440721-16460078 "Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 314.8;monocytes: 202.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028077 Approved Approved "Endoplasmic reticulum" No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Endoplasmic reticulum" "HPA028077: AB_10601273" "unprognostic (6.92e-2)" "unprognostic (4.45e-2)" "unprognostic (1.11e-1)" "unprognostic (2.73e-2)" "unprognostic (1.28e-1)" "unprognostic (4.35e-1)" "prognostic unfavorable (6.13e-4)" "unprognostic (5.48e-2)" "unprognostic (1.57e-1)" "unprognostic (3.38e-1)" "unprognostic (6.72e-2)" "unprognostic (1.70e-1)" "unprognostic (4.36e-2)" "unprognostic (1.39e-1)" "unprognostic (2.17e-1)" "unprognostic (5.58e-2)" "unprognostic (2.58e-2)" 38.1 37.9 28.4 51.7 31.0 29.0 34.3 30.7 32.8 31.6 29.5 30.9 23.4 22.8 19.2 43.5 32.8 30.5 22.2 27.0 30.4 33.2 31.7 51.7 77.6 34.6 29.5 36.8 22.1 23.7 19.8 59.9 31.5 25.4 29.5 14.2 26.6 21.0 8.6 45.7 32.0 30.2 32.0 73.3 30.5 33.7 32.5 55.9 25.7 12.8 63.3 44.4 31.1 32.7 54.1 29.2 30.5 36.0 60.6 65.0 17.9 59.6 83.3 76.8 67.9 32.1 87.1 47.8 70.4 111.2 35.4 35.8 43.1 60.3 63.9 100.0 44.3 46.7 33.4 44.6 78.9 59.8 41.7 73.0 61.6 54.7 44.9 66.2 129.1 54.4 67.0 153.7 69.1 35.3 55.8 63.3 26.6 41.1 41.9 61.2 27.0 79.6 76.9 30.5 19.1 48.6 46.4 27.1 61.9 45.1 30.9 66.1 148.0 49.2 26.8 57.4 41.1 72.5 74.5 47.9 41.6 85.7 49.0 90.2 173.1 112.3 96.1 241.2 95.6 108.8 165.8 114.5 120.1 98.8 168.2 106.6 68.2 121.6 274.7 71.0 214.7 269.9 28.4 31.0 30.7 32.8 27.0 30.4 34.6 29.5 31.5 32.0 32.5 32.7 53.6 22.4 25.0 10.1 47.6 52.3 34.1 60.4 27.3 25.7 37.9 35.1 7.0 22.8 32.2 20.2 314.8 49.0 42.5 34.6 23.5 71.3 61.1 27.0 29.5 67.8 18.7 40.8 7.0 54.2 62.0 33.3 23.9 27.6 27.8 33.0 96.4 11.0 125.7 15.2 7.7 31.8 36.7 94.5 81.8 34.3 29.8 60.5 24.9 7.5 202.0 23.8 55.6 11.6 11.4 121.9 45.8 33.8 24.3 46.6 30.8 22.8 37.4 54.3 39.5 14.7 27.2 26.8 27.4 33.3 56.0 49.4 59.4 72.7 24.0 58.8 NOMO1 PM5 ENSG00000103512 "NODAL modulator 1" Q15155 16 14833721-14896157 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 133.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 58.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 76.3;Hep G2: 126.5;LHCN-M2: 65.8;RPMI-8226: 90.4;SiHa: 144.9" "CAB025192, HPA046697, HPA061174" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 54: Cardiomyocytes - Muscle contraction" "Endoplasmic reticulum" "CAB025192: , HPA046697: AB_2679758, HPA061174: AB_2684444" "unprognostic (5.33e-3)" "unprognostic (1.60e-1)" "unprognostic (5.27e-1)" "unprognostic (1.12e-2)" "unprognostic (2.29e-1)" "unprognostic (1.51e-1)" "unprognostic (4.18e-3)" "unprognostic (2.08e-2)" "unprognostic (2.28e-1)" "unprognostic (2.76e-1)" "unprognostic (2.08e-2)" "unprognostic (8.31e-2)" "unprognostic (1.30e-2)" "unprognostic (1.09e-1)" "unprognostic (1.50e-2)" "unprognostic (2.51e-2)" "prognostic unfavorable (3.15e-4)" 24.1 27.6 4.4 10.3 4.4 0.0 23.6 4.4 16.0 22.0 4.4 32.3 0.7 25.6 0.0 24.9 20.4 0.4 92.3 4.5 9.6 32.0 28.3 26.9 2.7 4.8 4.3 21.3 133.9 0.0 29.2 6.8 4.5 21.6 8.2 4.2 31.1 4.5 101.7 28.1 26.1 8.2 4.3 19.9 36.4 31.0 4.5 0.0 21.5 1.4 0.2 28.8 22.2 5.1 1.2 56.8 51.4 76.3 0.0 4.6 42.2 3.4 9.1 11.5 11.0 0.8 2.8 4.3 2.8 8.8 1.0 0.7 8.8 0.7 11.3 6.2 0.0 3.7 57.8 126.5 48.7 5.8 2.7 0.6 0.5 6.2 6.3 1.2 9.0 0.0 29.7 2.6 65.8 0.0 1.6 0.0 0.0 0.0 0.0 1.9 4.3 90.4 0.0 2.6 1.1 45.8 144.9 0.0 0.1 1.7 63.1 0.6 2.1 1.9 0.1 2.6 58.1 0.3 2.1 4.7 2.3 2.3 1.3 3.7 0.2 0.2 0.0 0.4 0.3 0.0 0.1 0.3 0.1 0.5 0.2 0.3 0.6 1.9 2.0 1.6 0.3 0.6 4.4 4.4 4.4 16.0 4.5 9.6 4.8 4.3 4.5 4.3 4.5 5.1 5.6 3.2 10.5 9.1 5.3 6.4 1.4 10.6 3.4 8.7 7.8 5.8 58.4 7.2 8.6 11.0 6.2 6.8 4.2 14.4 0.0 15.6 32.9 3.3 3.1 7.3 7.7 5.5 12.7 29.4 12.4 7.9 11.7 4.2 23.6 13.0 7.9 7.6 6.3 35.3 16.2 11.7 2.0 12.7 2.8 12.0 2.8 10.3 5.4 7.5 11.2 5.4 16.5 13.6 32.1 27.4 10.8 6.4 16.2 2.1 16.1 7.9 7.4 8.5 6.6 5.7 7.5 16.1 13.1 6.7 5.8 9.6 4.2 9.5 13.0 1.6 NOTUM ENSG00000185269 "Notum, palmitoleoyl-protein carboxylesterase" Q6P988 17 81952507-81961840 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "placenta: 135.7" "Cell type enriched" "Detected in some" 45 "Extravillous trophoblasts: 1002.5" "Cancer enhanced" "Detected in many" "stomach cancer: 48.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "Hep G2: 428.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA022851 Approved "Endoplasmic reticulum" "Secreted in female reproductive system" NA NA 1900000 "Cluster 28: Placenta - Pregnancy" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 38: Extravillous trophoblasts - Unknown function" "Endoplasmic reticulum" "HPA022851: " "unprognostic (1.49e-1)" "unprognostic (1.55e-1)" "unprognostic (1.23e-2)" "unprognostic (4.80e-3)" "unprognostic (1.97e-1)" "unprognostic (9.02e-3)" "unprognostic (3.01e-2)" "unprognostic (1.01e-2)" "unprognostic (6.49e-2)" "unprognostic (8.72e-2)" "unprognostic (1.40e-1)" "unprognostic (2.01e-2)" "unprognostic (4.48e-6)" "unprognostic (1.76e-1)" "unprognostic (9.88e-2)" "unprognostic (1.22e-3)" "unprognostic (1.00e-1)" 0.0 0.1 1.6 0.0 1.9 0.0 0.2 0.6 1.8 0.2 0.1 0.0 1.1 2.1 0.3 0.3 0.4 0.2 0.3 1.0 1.0 1.2 10.0 2.2 0.0 1.7 2.7 0.1 0.4 0.9 0.2 135.7 1.3 0.3 0.0 0.0 0.6 0.1 8.2 2.2 0.3 0.1 0.9 0.2 2.1 2.8 1.3 0.0 0.0 0.5 0.0 1.4 0.2 0.8 0.0 1.2 0.0 0.0 0.0 0.0 1.3 0.1 0.2 0.0 0.1 10.0 0.4 0.0 1.8 0.3 0.2 0.4 2.4 0.0 0.0 0.1 1.1 2.2 2.8 428.6 0.2 0.4 0.4 0.2 0.0 0.0 0.0 0.6 0.0 0.2 11.2 0.0 0.0 0.6 0.0 0.2 0.1 67.9 0.4 0.0 0.2 0.1 0.0 0.2 15.7 1.6 4.2 1.7 6.2 2.3 0.1 4.9 0.0 0.5 6.3 0.0 0.2 0.1 0.0 1.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.9 0.6 1.8 1.0 1.0 1.7 2.7 1.3 0.9 1.3 0.8 0.0 0.0 3.7 0.3 0.0 0.1 0.1 0.1 0.0 0.0 0.6 1.3 1.2 0.0 0.0 0.0 0.0 10.0 0.0 0.1 0.0 0.0 0.4 0.1 0.1 0.8 0.0 0.0 0.6 0.0 1002.5 1.2 1.5 0.3 0.0 0.1 0.0 3.6 18.4 0.0 1.1 0.1 0.0 0.0 0.3 0.2 0.3 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.5 12.7 0.0 0.0 22.0 0.1 0.0 0.3 0.0 OGN "mimecan, OIF, SLRR3A" ENSG00000106809 Osteoglycin P20774 9 92383268-92404696 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 216.0" "Group enriched" "Detected in many" 8 "Endometrial stromal cells: 104.1;Fibroblasts: 326.2;Leydig cells: 166.2;Peritubular cells: 212.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "T-reg: 1.7" "Lineage enriched" "Detected in single" 9 "T-cells: 1.7" "Group enriched" "Detected in some" 4 "ASC TERT1: 22.2;HSkMC: 9.7;JURKAT: 15.7;MOLT-4: 32.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013132 Approved Supported "Endoplasmic reticulum" "Secreted in other tissues" NA NA 170000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 89: Fibroblasts - ECM organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA013132: AB_1854825" "unprognostic (2.31e-1)" "unprognostic (3.94e-3)" "unprognostic (1.74e-1)" "unprognostic (2.08e-2)" "unprognostic (2.60e-1)" "unprognostic (2.70e-1)" "unprognostic (1.44e-4)" "unprognostic (4.42e-2)" "unprognostic (1.01e-2)" "prognostic unfavorable (4.04e-4)" "unprognostic (2.47e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (1.92e-4)" "unprognostic (3.37e-3)" "unprognostic (3.86e-2)" "unprognostic (2.20e-3)" "prognostic unfavorable (2.03e-4)" 100.1 22.5 1.4 6.0 3.0 0.2 53.8 4.7 6.8 216.0 11.0 43.0 10.6 130.5 44.9 30.8 67.1 164.7 79.8 1.7 2.3 6.4 4.1 18.6 2.1 1.8 1.8 91.8 11.1 117.3 19.1 22.7 2.0 57.9 32.2 0.0 3.2 19.3 2.6 3.8 23.6 118.0 2.3 2.4 22.0 13.3 2.2 4.5 14.7 22.0 5.6 54.0 23.3 2.1 0.0 0.0 0.0 0.0 4.4 22.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.0 9.7 0.0 0.0 0.0 0.0 0.0 15.7 0.0 0.0 0.0 0.1 32.2 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.0 1.4 3.0 4.7 6.8 1.7 2.3 1.8 1.8 2.0 2.3 2.2 2.1 10.3 6.4 1.5 1.0 0.4 4.2 0.1 0.0 1.2 0.6 0.7 0.4 2.6 10.0 7.4 3.7 0.0 2.0 0.6 0.1 0.0 0.0 1.2 2.9 104.1 5.2 0.0 0.0 1.9 0.0 1.7 326.2 7.7 1.7 1.3 0.0 20.0 0.1 4.6 0.0 1.8 0.0 0.0 0.3 11.1 4.2 166.2 2.3 1.8 16.9 0.2 0.1 0.0 2.0 1.6 0.0 0.0 212.1 0.7 0.4 0.0 0.0 2.9 0.2 6.6 4.7 22.7 0.6 0.6 0.7 4.5 5.7 2.1 1.6 0.0 0.2 ORMDL1 ENSG00000128699 "ORMDL sphingolipid biosynthesis regulator 1" Q9P0S3 2 189770267-189784364 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA065643 Supported "Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 51: Non-specific - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 52: Non-specific - Transcription" "Endoplasmic reticulum" "HPA065643: AB_2685525" "unprognostic (1.45e-1)" "unprognostic (5.34e-3)" "unprognostic (1.05e-1)" "unprognostic (1.08e-1)" "unprognostic (2.56e-1)" "unprognostic (1.80e-1)" "unprognostic (4.85e-3)" "unprognostic (1.86e-2)" "unprognostic (6.70e-3)" "prognostic favorable (3.04e-5)" "unprognostic (5.90e-3)" "unprognostic (2.16e-2)" "prognostic unfavorable (5.84e-9)" "unprognostic (2.62e-1)" "unprognostic (1.14e-1)" "unprognostic (2.87e-2)" "prognostic favorable (1.49e-5)" 60.0 66.2 27.0 50.3 28.6 51.7 54.9 34.2 33.2 67.9 36.2 60.7 41.1 56.5 99.5 46.1 55.3 47.4 37.8 28.4 33.1 55.2 68.7 66.9 75.2 27.3 27.7 50.8 84.5 42.3 79.3 63.1 28.2 62.2 50.1 82.0 66.1 47.3 41.5 84.3 84.9 43.9 30.4 131.2 64.0 58.8 28.8 44.2 62.9 23.9 69.4 50.3 51.7 32.8 31.4 20.5 68.0 54.8 88.2 100.4 70.3 64.9 61.7 71.0 71.5 41.9 51.7 57.8 44.7 49.9 36.7 52.1 43.4 42.0 77.5 65.6 55.2 82.3 106.2 61.9 102.6 65.8 63.8 113.1 51.6 61.8 70.6 99.0 58.4 57.9 48.3 85.9 72.9 28.6 58.6 127.0 60.7 32.4 86.4 46.4 50.2 78.7 87.4 49.3 43.6 51.4 33.8 32.0 74.3 78.3 38.7 73.3 61.6 70.1 48.1 44.9 65.7 82.9 66.6 55.4 76.4 68.7 38.6 49.4 32.7 39.8 35.8 39.5 33.7 37.9 39.3 36.5 26.7 35.4 45.0 40.9 13.3 29.4 48.3 46.1 46.1 33.5 27.0 28.6 34.2 33.2 28.4 33.1 27.3 27.7 28.2 30.4 28.8 32.8 80.4 80.1 50.2 41.4 90.9 56.3 55.1 95.6 26.7 138.3 69.8 76.7 34.4 41.5 65.5 36.8 175.2 212.4 141.2 36.0 33.2 58.7 42.8 58.0 63.9 61.8 42.4 38.7 53.6 67.3 73.0 58.1 24.5 47.3 45.6 84.3 47.5 37.4 86.9 65.6 60.1 37.2 101.7 126.8 60.9 18.9 74.3 83.3 39.2 33.7 96.4 107.7 117.4 57.8 49.4 66.5 48.3 48.5 83.5 79.1 62.8 45.9 66.3 217.2 52.6 55.4 63.8 186.8 145.0 32.5 60.7 218.1 104.5 117.4 46.3 51.5 ORMDL2 "adoplin-2, HSPC160, MST095, MSTP095" ENSG00000123353 "ORMDL sphingolipid biosynthesis regulator 2" Q53FV1 12 55818041-55821879 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065643 Supported "Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Endoplasmic reticulum" "HPA065643: AB_2685525" "unprognostic (1.12e-1)" "unprognostic (2.59e-2)" "unprognostic (2.41e-1)" "prognostic favorable (3.30e-5)" "unprognostic (6.92e-2)" "unprognostic (1.52e-3)" "prognostic unfavorable (9.75e-4)" "unprognostic (1.45e-2)" "unprognostic (1.11e-1)" "unprognostic (2.88e-2)" "unprognostic (1.84e-3)" "unprognostic (1.49e-1)" "unprognostic (2.75e-3)" "unprognostic (1.25e-1)" "unprognostic (2.20e-1)" "unprognostic (3.04e-2)" "unprognostic (5.68e-2)" 37.5 38.1 14.6 24.2 17.0 20.4 31.3 18.3 20.5 30.0 24.7 44.5 27.2 28.4 51.3 75.9 26.3 20.6 30.1 14.8 18.4 40.7 47.5 35.5 23.0 19.0 18.0 16.8 32.9 44.5 29.7 22.3 18.5 30.8 48.4 14.8 40.2 23.2 19.7 36.4 30.2 26.4 17.2 33.2 32.9 42.7 18.3 27.6 27.4 11.1 38.5 41.7 36.8 20.2 55.9 103.5 43.1 22.4 81.2 40.4 47.7 66.5 66.0 57.0 49.9 116.6 133.8 34.5 69.3 80.7 58.5 100.3 34.6 138.7 56.6 35.9 51.4 46.7 89.7 65.9 85.8 56.7 47.4 50.9 125.2 99.9 103.3 73.3 81.0 38.2 25.0 91.1 73.7 89.3 34.8 25.3 20.9 87.8 82.0 22.8 34.5 88.4 149.8 159.1 37.4 23.8 84.9 99.9 38.4 64.8 120.0 40.1 59.4 30.5 42.6 36.4 42.7 43.6 39.1 28.1 48.9 22.4 43.1 50.4 73.0 107.1 86.5 92.8 76.8 93.2 82.1 92.1 73.4 76.1 67.8 81.5 91.8 74.1 108.7 119.9 107.8 72.1 14.6 17.0 18.3 20.5 14.8 18.4 19.0 18.0 18.5 17.2 18.3 20.2 43.1 73.7 38.3 1.3 39.8 23.3 71.9 132.9 15.4 9.9 43.1 30.0 3.9 45.8 99.4 53.3 12.5 74.7 49.6 125.7 29.4 133.7 171.0 77.9 25.7 42.0 46.1 26.5 0.7 168.1 117.5 22.0 28.1 86.0 51.9 14.0 35.3 82.2 125.3 8.4 0.8 66.7 69.2 42.5 49.1 68.0 25.4 57.4 56.9 2.8 111.4 24.8 77.2 1.0 4.0 197.4 133.5 23.3 50.8 95.7 89.7 76.0 149.2 18.4 19.7 13.5 32.9 107.0 61.7 50.6 33.4 151.6 44.6 30.5 56.2 91.3 ORMDL3 ENSG00000172057 "ORMDL sphingolipid biosynthesis regulator 3" Q8N138 17 39921041-39927601 "Disease related genes, Predicted membrane proteins" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 234.5" "Cell type enhanced" "Detected in many" "Early spermatids: 251.6;Late spermatids: 328.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 427.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065643 Supported "Endoplasmic reticulum" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 34: Spermatids - Unknown function" "Endoplasmic reticulum" "HPA065643: AB_2685525" "unprognostic (2.28e-1)" "unprognostic (1.06e-1)" "unprognostic (3.31e-2)" "unprognostic (6.49e-2)" "unprognostic (4.11e-2)" "unprognostic (1.55e-1)" "unprognostic (2.96e-1)" "prognostic favorable (9.29e-4)" "unprognostic (1.26e-1)" "unprognostic (3.67e-1)" "unprognostic (5.68e-2)" "unprognostic (1.14e-1)" "unprognostic (1.31e-1)" "unprognostic (2.37e-1)" "unprognostic (4.55e-1)" "unprognostic (1.09e-3)" "prognostic favorable (5.18e-4)" 149.0 29.6 39.6 33.9 39.5 39.7 70.8 37.2 45.8 40.1 55.9 41.9 50.0 36.1 64.7 28.4 28.0 32.4 63.0 41.7 40.2 38.0 234.5 49.0 55.9 40.9 38.6 39.9 109.6 51.1 50.2 35.5 38.3 46.9 38.6 25.1 70.4 41.6 44.2 41.4 47.8 36.6 40.1 38.3 50.0 50.8 41.6 79.4 57.7 29.5 56.4 46.9 26.3 39.1 33.5 40.2 41.8 34.8 106.1 40.2 37.9 48.0 55.4 50.5 48.4 46.1 36.3 24.7 44.6 59.4 34.5 56.0 29.8 38.6 46.9 427.6 53.2 24.1 22.5 113.0 41.5 28.5 40.6 44.2 39.7 34.9 19.7 57.2 22.8 68.5 30.9 194.8 28.0 30.1 85.1 31.9 23.4 44.2 20.1 71.2 37.7 78.4 28.2 80.1 36.6 37.2 31.8 196.6 32.9 46.3 70.8 30.8 18.7 27.4 34.0 23.6 36.8 104.2 95.3 34.5 28.2 27.6 20.6 9.3 4.7 61.1 39.4 7.7 28.3 26.4 39.3 43.3 4.2 23.1 44.2 53.7 7.7 18.4 11.6 21.1 27.7 36.6 39.6 39.5 37.2 45.8 41.7 40.2 40.9 38.6 38.3 40.1 41.6 39.1 7.6 51.3 37.2 2.9 28.7 16.4 13.7 13.1 21.6 18.5 25.9 14.5 28.9 17.2 15.3 42.3 0.0 25.9 18.4 27.3 3.9 18.4 251.6 7.2 12.6 10.3 25.9 34.1 3.4 29.2 17.9 13.9 11.2 13.8 18.4 10.5 7.5 97.8 8.3 13.5 3.8 26.8 18.3 7.5 13.0 328.9 18.6 6.0 16.0 1.9 22.1 44.9 57.7 3.5 3.2 38.8 20.8 28.6 41.2 15.2 29.2 11.9 8.0 11.2 26.3 8.5 16.5 5.8 7.6 11.5 14.3 9.3 35.6 21.0 17.7 12.4 OS9 "ERLEC2, OS-9" ENSG00000135506 "OS9 endoplasmic reticulum lectin" Q13438 12 57693955-57721557 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 7 "RH-30: 3551.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011518, HPA013694" Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA 10000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "CAB011518: AB_776918, HPA013694: AB_1854812" "unprognostic (1.67e-2)" "unprognostic (4.20e-1)" "unprognostic (3.93e-2)" "unprognostic (1.50e-1)" "unprognostic (9.79e-3)" "unprognostic (1.32e-3)" "unprognostic (4.78e-2)" "unprognostic (8.54e-2)" "unprognostic (2.67e-1)" "unprognostic (1.64e-1)" "unprognostic (5.67e-3)" "unprognostic (2.23e-1)" "unprognostic (1.83e-2)" "unprognostic (2.78e-1)" "unprognostic (1.67e-2)" "unprognostic (4.81e-2)" "unprognostic (2.21e-2)" 151.0 93.0 61.1 118.6 59.3 149.0 113.4 60.7 60.8 135.6 94.3 158.1 149.9 101.2 141.4 105.2 109.6 106.2 111.0 58.4 71.5 114.8 264.5 130.0 89.7 64.5 62.8 124.6 270.0 171.6 71.5 141.3 63.5 116.4 132.6 75.5 189.0 102.1 59.6 119.8 143.2 110.2 60.8 106.0 137.2 38.9 66.7 72.6 129.4 65.5 94.2 119.7 103.5 63.7 86.8 170.8 86.2 214.4 440.4 295.6 190.5 211.9 268.4 153.4 154.6 180.2 274.5 110.0 345.3 255.2 118.5 152.9 81.3 137.5 121.2 142.0 97.6 124.0 115.3 164.8 287.1 196.9 307.3 273.7 217.6 150.7 152.6 529.4 258.6 71.7 96.0 427.9 162.2 149.5 53.7 239.7 97.7 172.0 121.2 69.8 3551.9 281.5 116.5 210.6 88.4 116.4 300.3 205.5 176.6 158.1 245.4 381.0 238.9 206.0 122.3 140.4 136.4 253.4 234.6 112.9 173.8 141.6 290.4 175.7 241.2 274.6 72.9 213.0 68.5 50.5 61.1 65.0 172.6 54.3 46.8 54.1 246.4 58.8 182.4 149.0 74.4 218.9 61.1 59.3 60.7 60.8 58.4 71.5 64.5 62.8 63.5 60.8 66.7 63.7 83.3 86.6 116.7 22.2 65.8 57.7 85.4 103.3 43.9 44.1 61.2 46.6 14.1 80.1 111.8 73.5 77.2 142.4 64.5 153.0 9.8 144.8 6.7 34.0 73.3 90.2 103.6 53.4 19.5 110.1 124.6 113.6 65.7 60.0 91.1 61.6 81.4 161.1 144.8 50.5 27.0 167.3 107.8 121.1 99.1 10.7 113.4 106.1 119.2 29.0 125.0 87.2 53.5 23.6 24.4 94.7 155.4 79.0 141.1 56.5 154.0 53.9 74.0 50.9 92.1 68.3 66.9 38.1 46.4 51.3 51.6 197.7 59.5 64.9 102.4 65.0 P2RX1 P2X1 ENSG00000108405 "Purinergic receptor P2X 1" P51575 17 3896592-3916476 "Predicted membrane proteins" "Apoptosis, Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 42.0;pancreas: 65.1;urinary bladder: 75.5" "Cell type enriched" "Detected in some" 5 "granulocytes: 185.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 46.3" "Group enriched" "Detected in many" 30 "dendritic cells: 15.1;granulocytes: 23.5;monocytes: 46.3" "Cell line enhanced" "Detected in some" "HEL: 13.8;HMC-1: 8.4;Karpas-707: 16.8;THP-1: 14.7;U-937: 7.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "midbrain: 1.3" HPA057678 Approved "Endoplasmic reticulum" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Endoplasmic reticulum" "HPA057678: " "unprognostic (1.27e-3)" "unprognostic (1.61e-2)" "unprognostic (2.65e-1)" "unprognostic (3.54e-2)" "unprognostic (7.34e-3)" "unprognostic (9.89e-5)" "unprognostic (1.77e-2)" "unprognostic (6.15e-3)" "unprognostic (2.98e-1)" "unprognostic (2.52e-3)" "unprognostic (1.90e-1)" "unprognostic (2.20e-2)" "unprognostic (4.47e-3)" "unprognostic (2.60e-1)" "unprognostic (5.58e-2)" "unprognostic (4.29e-1)" "unprognostic (1.09e-2)" 9.8 2.0 0.5 4.4 0.8 42.0 1.5 0.8 0.7 7.7 0.4 13.4 9.3 7.3 1.8 23.0 3.9 2.0 2.0 0.5 0.7 1.0 0.7 4.8 2.9 0.8 0.9 2.1 65.1 0.1 0.3 3.8 0.8 10.7 9.2 0.1 1.6 34.1 0.5 5.9 9.0 6.0 0.7 13.0 2.8 2.6 0.6 2.0 0.4 0.3 3.2 75.5 8.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.8 0.2 0.1 1.1 1.8 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.8 0.0 0.0 0.1 3.3 0.0 0.4 0.0 2.1 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.7 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.1 7.4 0.0 0.0 10.8 11.9 0.0 20.4 0.0 0.4 0.0 0.0 5.9 0.9 0.0 0.0 23.5 0.0 46.3 15.1 0.0 8.2 0.5 0.8 0.8 0.7 0.5 0.7 0.8 0.9 0.8 0.7 0.6 1.0 0.1 3.2 4.2 0.7 15.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.3 0.0 0.0 0.1 8.9 0.0 0.0 0.1 0.1 0.0 0.0 0.7 0.0 18.5 0.3 2.0 0.1 0.9 0.5 0.0 185.4 0.0 0.0 0.0 3.6 0.0 0.2 0.1 0.0 5.1 2.4 0.2 0.0 22.5 0.0 1.0 7.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 36.0 0.0 0.0 0.1 0.7 0.0 0.0 0.4 3.4 0.0 0.1 0.1 0.9 0.0 1.8 0.5 0.3 0.0 P4HB "DSI, ERBA2L, GIT, P4Hbeta, PDI, PDIA1, PO4DB, PO4HB, PROHB" ENSG00000185624 "Prolyl 4-hydroxylase subunit beta" P07237 17 81843159-81860856 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Chaperone, Isomerase" "Craniosynostosis, Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1856.8;pancreas: 2446.9" "Cell type enhanced" "Detected in all" "Exocrine glandular cells: 1077.9;Extravillous trophoblasts: 1349.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012463, HPA018884" Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" No No 110000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "CAB012463: , HPA018884: AB_1854896" "unprognostic (9.47e-3)" "unprognostic (1.09e-2)" "unprognostic (2.99e-2)" "unprognostic (7.14e-3)" "unprognostic (7.75e-3)" "unprognostic (1.05e-2)" "unprognostic (1.30e-1)" "unprognostic (5.26e-2)" "unprognostic (1.22e-1)" "unprognostic (4.73e-3)" "unprognostic (1.43e-1)" "unprognostic (3.93e-2)" "prognostic unfavorable (2.30e-11)" "unprognostic (1.18e-1)" "unprognostic (1.04e-2)" "unprognostic (4.99e-3)" "unprognostic (3.19e-3)" 266.5 507.8 34.6 209.8 35.7 517.1 225.5 39.1 35.7 272.0 59.6 258.4 640.2 206.5 133.0 618.7 183.4 202.0 318.4 31.7 50.2 270.7 1856.8 301.3 104.0 48.9 37.1 187.8 2446.9 144.3 330.0 334.3 40.8 335.8 173.6 23.3 948.1 184.2 328.5 370.4 554.7 179.8 39.8 428.6 539.2 68.8 58.7 89.3 244.8 150.8 137.9 233.7 322.9 43.7 690.3 580.7 236.8 687.5 813.4 726.7 593.6 1038.5 1081.1 741.9 934.5 550.4 576.9 264.4 501.8 1120.2 407.5 464.1 248.8 647.4 254.1 145.8 320.5 355.2 362.9 953.6 1010.8 1146.4 613.4 618.8 494.8 478.2 596.7 843.0 1250.1 182.1 273.6 978.2 559.5 566.4 260.5 723.2 157.7 791.0 463.8 261.8 342.5 614.0 453.2 492.8 248.7 301.1 586.1 1693.1 808.1 289.6 855.3 1601.2 644.1 980.5 503.1 574.3 586.6 743.5 407.9 204.8 1372.0 591.3 825.4 198.3 268.1 163.0 202.6 154.4 209.8 83.9 138.9 165.7 174.7 68.1 74.9 114.6 72.9 157.0 115.3 311.5 105.6 372.4 34.6 35.7 39.1 35.7 31.7 50.2 48.9 37.1 40.8 39.8 58.7 43.7 122.3 102.5 162.1 23.2 151.4 120.1 163.6 371.0 140.6 59.2 283.0 170.8 24.1 247.4 211.7 112.2 33.3 790.2 208.9 420.7 41.1 671.9 43.5 78.4 196.8 153.9 199.9 140.9 15.3 1077.9 1349.1 272.5 388.9 209.1 99.1 210.4 190.2 840.7 435.9 62.2 16.2 610.9 189.2 186.9 125.5 64.9 141.4 180.3 136.9 20.6 263.3 122.7 230.7 13.6 19.6 575.2 465.6 112.1 664.3 310.6 914.2 105.0 91.3 54.3 157.8 103.4 226.7 83.4 94.1 302.3 144.6 1001.2 138.8 378.4 475.4 220.8 PCNX2 "FLJ11383, KIAA0435, PCNXL2" ENSG00000135749 "Pecanex 2" A6NKB5 1 232983435-233295725 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 9.6;Collecting duct cells: 12.9;Endometrial ciliated cells: 9.3;Endometrial stromal cells: 8.8;Glandular and luminal cells: 11.1;Granulosa cells: 8.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013815, HPA014427" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 5: NTERA-2 - Transcription" "Cluster 7: Non-specific - Mitochondria" "Endoplasmic reticulum" "HPA013815: AB_2236561, HPA014427: AB_1855081" "unprognostic (3.15e-1)" "unprognostic (5.61e-3)" "unprognostic (1.92e-2)" "unprognostic (1.44e-2)" "unprognostic (2.54e-1)" "unprognostic (1.31e-1)" "unprognostic (1.58e-2)" "unprognostic (1.71e-1)" "unprognostic (4.25e-2)" "unprognostic (3.79e-1)" "unprognostic (2.40e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (2.27e-5)" "unprognostic (1.12e-1)" "unprognostic (2.92e-2)" "unprognostic (1.49e-2)" "unprognostic (1.29e-1)" 4.2 2.1 8.4 2.5 8.9 2.2 3.8 6.2 18.3 4.0 0.0 2.3 1.5 3.1 6.6 3.6 4.2 3.9 1.7 15.7 1.8 4.8 0.6 2.5 5.0 1.9 4.7 7.1 4.5 3.6 14.8 1.0 2.5 4.7 2.1 11.5 4.7 3.6 3.1 4.7 5.2 2.4 0.3 3.9 3.4 2.8 8.2 3.3 5.6 0.6 3.7 4.7 5.1 6.8 5.1 12.0 6.4 0.1 10.3 11.1 1.9 3.0 8.6 3.1 5.3 3.9 6.0 10.5 6.8 8.1 11.1 8.2 2.9 8.5 7.1 8.9 8.7 0.1 6.6 0.0 4.6 3.5 2.0 8.5 7.4 6.0 23.6 10.3 5.8 7.7 0.0 5.5 3.0 3.0 9.8 0.2 20.7 4.2 7.2 0.1 1.7 1.5 5.5 7.7 11.0 9.2 4.4 1.8 1.8 3.6 4.3 0.9 2.2 8.4 5.4 9.6 9.9 6.5 7.3 0.1 7.7 3.8 9.9 0.3 0.2 0.1 0.7 0.1 0.5 0.3 0.6 0.7 0.5 0.3 0.2 0.5 0.1 0.2 0.1 0.1 0.7 0.3 8.4 8.9 6.2 18.3 15.7 1.8 1.9 4.7 2.5 0.3 8.2 6.8 7.0 9.6 5.9 0.0 1.6 0.0 0.0 0.0 0.0 0.0 6.9 7.4 0.0 0.0 6.8 12.9 0.0 0.4 5.8 0.0 7.9 6.4 0.0 9.3 8.8 1.1 0.0 0.0 0.0 3.3 1.6 3.6 0.0 11.1 1.3 8.9 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 5.6 0.0 0.0 1.7 0.0 0.0 1.7 4.4 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.3 6.5 4.3 0.0 0.0 PDE3B HcGIP1 ENSG00000152270 "Phosphodiesterase 3B" Q13370 11 14643804-14872044 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins" Angiogenesis Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 64.5" "Cell type enhanced" "Detected in many" "Astrocytes: 171.7;Excitatory neurons: 140.5;Inhibitory neurons: 158.0;Microglial cells: 192.0;Oligodendrocyte precursor cells: 118.6" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 5 "cerebellum: 13.5" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "granulocytes: 3.8;T-cells: 6.3" "Cell line enhanced" "Detected in many" "HL-60: 23.5;Karpas-707: 25.7;THP-1: 28.4;U-266/70: 28.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056111 Approved "Endoplasmic reticulum" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 29: U-266 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Endoplasmic reticulum" "HPA056111: AB_2683041" "unprognostic (1.05e-1)" "unprognostic (2.86e-2)" "unprognostic (4.12e-2)" "unprognostic (2.76e-3)" "unprognostic (4.25e-1)" "unprognostic (1.84e-3)" "unprognostic (3.40e-2)" "unprognostic (3.24e-2)" "unprognostic (5.39e-2)" "unprognostic (1.20e-1)" "prognostic favorable (7.91e-4)" "unprognostic (1.77e-1)" "unprognostic (2.33e-2)" "unprognostic (1.39e-2)" "unprognostic (3.42e-1)" "unprognostic (2.47e-1)" "unprognostic (9.03e-3)" 64.5 1.1 1.3 12.4 2.1 10.1 12.2 13.5 2.6 3.4 0.0 25.2 2.9 0.7 0.5 2.9 0.5 3.7 4.7 1.9 2.6 3.0 25.8 10.2 14.9 2.8 1.7 0.5 8.3 0.2 4.4 7.6 1.9 8.7 10.7 0.5 14.0 1.6 0.4 0.5 6.0 1.7 2.3 8.9 2.6 9.6 2.0 7.3 0.8 2.4 7.9 8.5 1.9 2.6 0.0 2.5 5.6 9.2 10.9 0.1 2.2 0.6 0.1 0.0 0.0 8.5 0.0 0.0 0.1 0.0 2.6 0.0 8.5 0.0 0.0 0.2 18.7 0.3 13.1 17.5 3.9 23.5 0.1 0.8 0.0 0.0 0.5 0.0 0.1 6.6 20.6 25.7 0.0 0.3 4.7 11.4 7.6 3.1 4.1 11.0 2.5 17.7 0.0 1.9 8.5 15.8 2.3 14.6 5.1 2.5 0.0 28.4 0.0 0.0 1.3 0.0 0.0 28.8 9.4 0.7 0.2 4.0 1.7 0.0 0.5 2.5 1.0 0.6 2.1 0.2 3.1 2.4 0.3 0.1 6.3 5.7 3.8 0.1 1.0 0.1 3.5 1.5 1.3 2.1 13.5 2.6 1.9 2.6 2.8 1.7 1.9 2.3 2.0 2.6 1.5 16.0 8.9 171.7 6.4 0.3 0.9 0.0 0.6 1.0 0.3 0.3 11.1 0.0 6.2 1.8 0.0 1.4 26.7 11.5 1.9 0.0 19.0 0.3 5.1 4.0 1.2 12.8 140.5 5.0 2.8 9.7 7.7 0.3 36.1 0.5 4.2 64.1 7.6 0.0 158.0 13.7 0.0 13.1 3.7 13.4 1.5 15.6 0.0 192.0 10.8 6.3 8.2 118.6 5.4 1.8 22.3 9.1 28.9 3.3 0.7 2.0 3.6 0.5 0.0 3.4 3.0 48.8 19.5 0.1 0.1 2.5 60.9 0.0 9.4 1.1 PDIA3 "ERp57, ERp60, ERp61, GRP57, GRP58, HsT17083, P58, PI-PLC" ENSG00000167004 "Protein disulfide isomerase family A member 3" P30101 15 43746410-43773278 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 1048.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002645, HPA003230, CAB011199, CAB015181, CAB075744" Enhanced Enhanced "Endoplasmic reticulum" "Intracellular and membrane" NA NA 200000000 "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "CAB011199: AB_609902, CAB015181: AB_2160857, CAB075744: AB_2665750, HPA002645: AB_1079031, HPA003230: AB_1079030" "unprognostic (9.20e-2)" "unprognostic (1.21e-3)" "unprognostic (1.34e-1)" "prognostic favorable (2.05e-4)" "unprognostic (2.40e-2)" "prognostic unfavorable (8.95e-5)" "unprognostic (1.67e-1)" "unprognostic (8.60e-2)" "unprognostic (2.65e-1)" "unprognostic (2.24e-1)" "unprognostic (1.84e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (2.11e-8)" "unprognostic (1.82e-1)" "unprognostic (1.73e-1)" "unprognostic (1.19e-1)" "unprognostic (6.63e-2)" 17.0 16.6 7.5 16.5 8.0 27.1 15.6 9.2 7.6 24.7 13.9 20.6 23.6 16.4 44.7 18.9 15.4 13.5 17.3 7.7 9.8 15.3 34.5 16.8 18.7 9.3 8.2 16.5 36.0 22.6 16.2 23.8 9.1 25.2 22.5 8.4 21.6 19.1 7.6 17.3 21.4 17.0 9.0 12.5 20.4 10.8 9.3 9.6 56.0 4.1 12.3 15.6 15.2 9.8 29.4 11.9 24.6 55.1 48.9 51.9 70.8 58.6 62.1 46.0 56.7 33.6 32.1 33.8 37.4 72.9 30.8 47.8 31.8 61.5 39.7 24.3 44.7 47.2 17.6 30.9 80.1 26.0 33.8 33.6 49.8 35.0 58.5 54.0 81.3 11.1 27.7 17.4 45.5 11.1 9.1 30.4 24.4 48.5 44.0 17.9 36.7 26.2 39.3 26.0 22.9 25.4 48.7 49.0 19.4 25.0 33.1 28.1 50.9 37.7 18.9 29.7 29.1 7.1 8.6 33.9 48.1 41.2 28.8 11.6 8.8 13.3 12.1 9.2 12.8 5.4 6.8 9.5 8.3 6.1 6.0 7.1 2.4 12.7 9.9 17.6 5.8 15.8 7.5 8.0 9.2 7.6 7.7 9.8 9.3 8.2 9.1 9.0 9.3 9.8 224.9 192.3 183.9 31.6 177.8 192.2 313.7 665.2 114.4 56.5 137.9 95.5 58.3 124.4 427.7 167.3 41.7 655.2 319.6 228.7 70.5 401.2 24.3 178.8 300.3 223.7 186.1 95.3 29.2 390.4 807.8 350.7 261.0 328.5 261.6 255.1 233.1 342.2 426.0 70.7 38.3 523.1 231.9 157.3 292.2 26.7 253.5 246.5 243.7 36.5 258.0 128.3 279.1 29.7 38.8 279.9 196.8 276.8 341.1 286.5 234.3 129.1 245.6 61.9 124.9 138.4 389.7 186.4 147.6 138.9 148.5 1048.8 237.8 390.8 335.4 291.7 PDIA4 "ERP70, ERP72" ENSG00000155660 "Protein disulfide isomerase family A member 4" P13667 7 149003062-149028662 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 386.7;Hepatocytes: 595.4;Plasma cells: 556.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006139, HPA006140, CAB017368" Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA 15000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "CAB017368: AB_10621725, HPA006139: AB_1848256, HPA006140: AB_1848257" "unprognostic (1.98e-1)" "unprognostic (1.62e-2)" "unprognostic (1.77e-1)" "unprognostic (1.87e-2)" "prognostic unfavorable (9.69e-4)" "unprognostic (1.97e-2)" "unprognostic (1.81e-1)" "unprognostic (2.11e-2)" "unprognostic (5.11e-2)" "unprognostic (3.24e-3)" "unprognostic (6.08e-3)" "unprognostic (3.20e-2)" "prognostic unfavorable (5.20e-9)" "unprognostic (1.03e-1)" "unprognostic (1.53e-1)" "unprognostic (6.76e-2)" "unprognostic (2.51e-1)" 50.3 30.0 22.8 91.5 27.5 35.7 38.2 31.1 24.1 92.8 33.6 84.8 74.1 58.6 163.5 38.9 81.6 53.5 40.4 22.1 31.2 49.5 241.7 48.5 59.0 35.3 29.3 47.3 112.6 26.4 44.6 92.0 34.2 69.3 85.5 8.4 56.1 47.4 9.3 30.0 66.3 71.9 29.6 63.6 95.6 30.8 33.8 46.7 234.1 10.1 72.4 65.6 33.3 49.8 251.3 236.0 249.8 703.3 223.2 158.2 358.2 343.5 230.5 194.8 314.5 196.6 661.5 179.4 748.2 287.0 532.2 160.1 170.6 329.1 168.9 129.0 99.0 86.6 62.7 436.6 298.4 198.5 233.9 156.4 145.1 213.6 169.8 251.7 401.0 90.6 143.6 476.1 173.4 276.4 190.9 226.0 371.1 510.9 134.0 123.6 192.5 440.5 228.2 194.9 79.1 207.6 313.0 223.7 124.1 295.7 127.4 151.9 220.6 152.1 84.5 372.0 247.5 357.5 173.7 125.5 354.2 231.1 528.9 74.4 80.5 51.0 130.4 85.6 135.4 99.1 83.7 100.8 77.6 58.2 77.4 82.7 11.0 91.9 91.4 251.8 68.7 160.6 22.8 27.5 31.1 24.1 22.1 31.2 35.3 29.3 34.2 29.6 33.8 49.8 43.3 28.9 36.2 6.8 87.9 34.7 88.0 142.5 29.0 4.2 50.8 31.5 31.0 95.8 92.4 42.3 4.2 177.8 86.9 135.4 15.6 129.0 3.1 91.1 93.1 57.0 61.6 41.2 3.2 91.0 386.7 102.8 119.8 107.1 57.8 72.0 81.4 595.4 147.9 0.0 5.7 282.9 61.1 84.7 49.6 5.5 59.0 55.3 87.2 9.4 51.8 15.6 68.0 4.5 11.9 94.5 88.6 42.9 556.7 108.1 71.3 66.3 114.8 6.7 32.9 35.2 66.0 47.6 86.1 29.2 28.6 230.4 46.7 52.4 155.6 72.4 PEDS1 "CarF, Kua, TMEM189" ENSG00000240849 "Plasmanylethanolamine desaturase 1" A5PLL7 20 50118254-50153734 "Enzymes, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 86.8;Extravillous trophoblasts: 167.6;Hofbauer cells: 38.6;Syncytiotrophoblasts: 50.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059549 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Endoplasmic reticulum" "HPA059549: AB_2684059" "unprognostic (3.11e-2)" "unprognostic (7.04e-3)" "unprognostic (1.56e-2)" "prognostic unfavorable (7.51e-4)" "unprognostic (1.71e-1)" "unprognostic (1.04e-1)" "unprognostic (2.03e-3)" "unprognostic (7.00e-2)" "unprognostic (2.19e-2)" "unprognostic (1.35e-1)" "unprognostic (8.63e-2)" "unprognostic (5.79e-2)" "prognostic unfavorable (5.79e-11)" "unprognostic (1.85e-1)" "unprognostic (1.20e-1)" "unprognostic (9.46e-2)" "unprognostic (4.42e-2)" 13.2 14.0 19.6 7.3 24.0 5.7 10.4 25.3 24.3 12.7 15.8 18.4 8.7 13.8 10.7 26.0 9.1 7.2 20.8 19.6 20.8 9.3 17.8 13.7 6.0 25.8 24.4 5.5 9.3 12.8 5.8 17.6 24.1 11.6 7.1 2.2 12.4 13.5 16.9 22.9 9.8 21.8 21.0 10.0 15.1 6.3 23.3 7.8 7.7 16.3 7.4 15.4 15.1 29.1 19.6 17.7 20.7 16.3 30.7 23.0 34.6 13.6 12.6 27.8 15.6 48.6 30.5 7.2 21.2 12.8 39.7 52.8 10.4 27.4 10.0 3.8 8.0 9.3 24.5 41.6 17.3 15.1 24.2 19.7 62.7 15.6 16.4 13.4 33.6 12.2 9.8 10.2 9.5 17.3 12.0 38.1 10.1 50.1 18.3 9.7 15.9 7.8 53.7 28.4 10.8 7.1 15.4 52.2 32.4 20.3 8.3 21.2 26.8 23.1 12.1 15.1 13.5 7.5 13.6 2.9 19.9 11.1 19.1 4.9 5.3 6.2 3.1 10.2 2.6 1.8 3.5 2.6 5.6 1.5 2.9 3.4 2.0 4.0 14.0 3.6 5.6 3.8 19.6 24.0 25.3 24.3 19.6 20.8 25.8 24.4 24.1 21.0 23.3 29.1 8.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.8 0.0 0.0 0.0 0.0 86.8 6.3 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 167.6 6.3 0.0 0.0 0.0 0.0 0.0 0.0 38.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 50.1 1.2 0.0 0.0 0.0 PFKM "PFK-1, PFKX, PPP1R122" ENSG00000152556 "Phosphofructokinase, muscle" P08237 12 48105139-48146404 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "skeletal muscle: 1570.1;tongue: 1393.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 345.9;Horizontal cells: 121.1;Muller glia cells: 125.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002117 Approved Approved "Endoplasmic reticulum" NA NA 410000 "Cluster 19: B-cells - Humoral immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Endoplasmic reticulum" "HPA002117: AB_1855245" "unprognostic (4.60e-2)" "unprognostic (2.56e-3)" "unprognostic (2.56e-3)" "prognostic unfavorable (5.85e-6)" "unprognostic (4.97e-1)" "prognostic unfavorable (7.91e-5)" "unprognostic (5.93e-3)" "unprognostic (1.63e-1)" "unprognostic (2.80e-1)" "unprognostic (1.86e-1)" "unprognostic (2.29e-3)" "unprognostic (6.73e-2)" "prognostic favorable (2.28e-7)" "unprognostic (1.07e-1)" "unprognostic (1.53e-1)" "unprognostic (5.72e-2)" "unprognostic (1.30e-2)" 18.7 54.2 50.4 11.0 50.9 8.0 15.0 58.1 59.3 28.2 50.1 34.2 10.4 36.1 14.3 38.6 29.2 15.9 298.6 49.4 63.3 46.0 8.4 14.9 8.0 54.5 51.1 45.1 10.9 136.2 36.5 12.0 58.7 29.0 16.1 85.5 29.2 39.0 1570.1 14.4 16.0 35.1 46.1 11.8 23.0 50.7 62.1 9.3 21.5 1393.9 10.2 27.7 19.2 43.4 32.9 30.6 98.4 87.5 97.2 72.5 20.2 85.4 80.2 77.1 54.4 76.3 40.5 192.9 69.6 44.1 44.9 36.0 90.1 91.2 70.9 5.5 43.9 54.7 64.7 1.9 54.3 2.9 30.9 102.1 50.4 69.2 107.3 125.1 85.9 3.7 64.6 91.7 71.5 25.8 69.5 5.1 67.7 36.0 93.9 115.7 55.7 141.3 48.4 32.5 111.5 82.6 51.0 75.9 86.5 78.7 80.3 11.2 75.8 34.0 46.5 49.5 72.1 52.8 145.3 106.4 62.4 6.8 28.5 0.3 2.9 7.8 2.1 2.5 0.9 8.8 3.5 2.1 5.6 8.3 4.3 2.4 0.7 2.1 2.1 0.9 3.5 3.1 50.4 50.9 58.1 59.3 49.4 63.3 54.5 51.1 58.7 46.1 62.1 43.4 8.6 16.0 8.4 30.3 6.9 7.4 21.7 22.1 15.9 43.3 5.6 9.1 345.9 12.8 10.8 22.0 43.8 2.8 0.9 3.4 66.5 10.6 43.1 5.5 18.0 17.3 9.1 8.6 23.2 2.5 3.8 27.1 6.6 2.4 1.3 17.3 13.9 2.7 4.1 121.1 30.0 9.1 34.6 3.8 3.7 27.0 30.7 4.3 55.2 3.7 11.3 125.7 4.1 15.6 3.4 3.5 1.9 47.8 4.6 7.9 2.7 30.6 11.2 51.1 26.3 37.6 24.5 52.1 14.4 9.2 5.3 2.5 3.3 24.0 10.1 9.7 PID1 "FLJ20701, NYGGF4" ENSG00000153823 "Phosphotyrosine interaction domain containing 1" Q7Z2X4 2 228850526-229271287 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 135.0;Inhibitory neurons: 142.2;Langerhans cells: 210.4;Microglial cells: 179.9;Oligodendrocyte precursor cells: 543.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 71.1;intermediate monocyte: 79.4;myeloid DC: 83.6" "Group enriched" "Detected in many" 53 "dendritic cells: 83.6;monocytes: 79.4" "Cell line enhanced" "Detected in many" "ASC diff: 54.5;hTEC/SVTERT24-B: 86.1;LHCN-M2: 57.3;REH: 62.3;RH-30: 90.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036103 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "HPA036103: AB_10602144" "unprognostic (8.46e-2)" "unprognostic (2.96e-1)" "unprognostic (3.55e-2)" "unprognostic (5.52e-2)" "unprognostic (9.40e-3)" "unprognostic (2.66e-2)" "unprognostic (1.21e-2)" "unprognostic (6.36e-2)" "unprognostic (1.54e-2)" "unprognostic (1.55e-2)" "unprognostic (2.52e-1)" "unprognostic (1.46e-1)" "unprognostic (4.91e-3)" "unprognostic (9.98e-3)" "unprognostic (1.11e-1)" "unprognostic (5.34e-2)" "unprognostic (9.61e-6)" 31.2 29.5 18.8 13.9 20.8 2.9 25.8 9.0 21.2 30.2 9.0 37.6 5.5 22.9 8.9 12.0 33.9 12.7 17.0 20.6 15.5 5.6 62.2 24.4 4.4 14.8 30.5 31.0 13.8 1.5 8.8 26.1 13.6 19.2 21.5 3.8 10.2 14.8 13.1 20.0 25.1 16.7 11.8 20.3 25.5 5.5 21.4 3.4 16.6 20.8 3.6 30.9 27.0 13.8 0.0 1.9 0.0 0.0 54.5 10.5 0.1 9.2 34.7 5.8 7.1 0.7 0.0 0.0 0.2 13.0 18.0 1.7 0.0 1.7 7.8 0.0 0.0 0.0 4.0 0.1 22.3 0.0 0.1 19.8 15.5 86.1 14.0 16.1 0.0 0.0 0.0 0.1 57.3 0.1 0.1 0.0 0.9 7.6 5.2 62.3 90.7 0.1 1.1 0.0 1.8 2.3 19.4 1.8 0.1 0.7 0.2 0.0 0.0 22.3 8.3 21.1 8.8 0.1 0.0 0.0 29.3 0.1 3.7 0.0 71.1 0.0 0.0 79.4 0.4 0.2 0.0 0.2 83.6 0.0 0.0 0.0 1.5 0.0 16.7 0.4 0.3 28.4 18.8 20.8 9.0 21.2 20.6 15.5 14.8 30.5 13.6 11.8 21.4 13.8 4.0 6.4 70.9 53.8 1.6 15.6 6.1 13.5 6.8 5.7 0.9 1.7 2.6 8.6 11.1 0.0 0.0 1.9 0.2 75.7 0.0 2.5 0.1 1.4 37.8 4.1 4.9 0.4 121.0 4.0 31.5 107.3 1.1 4.4 6.3 7.8 4.2 135.0 3.3 0.0 142.2 11.9 4.1 42.5 210.4 1.9 88.0 50.1 21.4 179.9 35.2 14.0 1.0 543.4 3.5 1.6 24.2 75.2 0.5 21.9 39.5 0.3 2.5 1.3 0.0 4.8 8.7 0.4 2.1 1.4 14.5 4.8 2.4 41.0 36.0 1.4 PMFBP1 ENSG00000118557 "Polyamine modulated factor 1 binding protein 1" Q8TBY8 16 72112157-72176878 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 20.9" "Group enriched" "Detected in some" 6 "Early spermatids: 115.6;Late spermatids: 259.5" "Low cancer specificity" "Detected in single" "Region enhanced" "Detected in many" "pons: 13.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 21.0;SH-SY5Y: 10.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA056716, HPA075825" Approved Uncertain "Endoplasmic reticulum" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 31: Spermatids - Spermatogenesis" "Endoplasmic reticulum" "HPA056716: AB_2683215, HPA075825: " "unprognostic (1.46e-1)" "unprognostic (3.62e-1)" "unprognostic (5.95e-2)" "unprognostic (1.04e-1)" "unprognostic (2.44e-2)" "unprognostic (7.03e-2)" "unprognostic (1.06e-4)" "unprognostic (1.60e-1)" "unprognostic (3.81e-1)" "unprognostic (2.67e-1)" "unprognostic (1.03e-1)" "unprognostic (2.82e-1)" "unprognostic (2.68e-5)" "unprognostic (9.85e-2)" "unprognostic (2.66e-1)" "unprognostic (9.85e-2)" "unprognostic (8.67e-2)" 1.7 2.2 0.4 1.3 0.9 4.5 1.5 2.5 0.8 1.8 0.5 3.2 2.9 1.7 13.5 2.9 2.0 0.9 3.3 0.8 1.9 3.0 3.1 1.6 2.0 3.5 3.9 2.6 6.5 1.2 2.7 0.6 13.3 3.6 3.3 3.5 1.7 0.3 0.6 4.4 3.9 0.3 1.9 4.7 2.6 20.9 1.0 2.4 2.1 0.0 0.5 1.8 1.9 1.4 0.2 0.4 2.8 2.8 0.0 0.6 1.9 0.6 0.2 0.6 2.1 1.1 2.8 1.9 0.4 0.1 0.1 1.8 1.0 0.1 1.4 0.2 4.3 1.9 3.7 3.1 0.0 4.2 3.2 0.0 0.9 0.1 2.1 0.6 0.8 2.3 0.4 1.7 0.1 2.4 1.1 6.8 0.8 0.1 1.2 2.9 0.2 1.5 0.3 0.8 21.0 10.7 0.0 0.0 0.2 2.0 0.5 2.7 1.8 1.3 2.2 0.6 1.4 3.9 1.5 1.2 0.6 2.8 0.7 0.0 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.4 0.9 2.5 0.8 0.8 1.9 3.5 3.9 13.3 1.9 1.0 1.4 0.0 0.0 0.6 1.0 0.3 0.4 0.1 0.1 1.2 0.9 0.1 0.0 0.7 0.0 1.3 0.0 0.0 0.0 0.1 0.3 0.0 0.2 115.6 0.3 0.2 0.3 5.4 0.8 0.7 0.2 0.1 0.6 0.0 0.1 3.8 0.3 0.0 0.1 4.7 30.3 0.7 0.7 0.0 1.9 5.5 259.5 1.2 2.4 0.0 1.0 0.0 1.1 0.0 1.0 1.6 0.1 0.1 1.5 0.0 0.1 0.2 0.6 1.6 0.2 0.0 0.0 0.1 2.9 0.9 0.3 0.0 0.1 1.0 0.0 0.9 0.2 POGLUT1 "9630046K23Rik, C3orf9, hCLP46, KDELCL1, KTELC1, MDS010, MDSRP, MGC32995, Rumi" ENSG00000163389 "Protein O-glucosyltransferase 1" Q8NBL1 3 119468963-119494708 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Gastrulation "Developmental protein, Glycosyltransferase, Transferase" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 81.2;monocytes: 151.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037855, HPA037856" Approved Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 25: RPMI-8226 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Endoplasmic reticulum" "HPA037855: AB_10672728, HPA037856: AB_2732477" "unprognostic (2.43e-1)" "unprognostic (5.94e-2)" "unprognostic (1.19e-1)" "unprognostic (1.83e-2)" "unprognostic (5.62e-2)" "unprognostic (2.00e-2)" "unprognostic (3.38e-1)" "unprognostic (2.81e-2)" "unprognostic (1.84e-2)" "unprognostic (1.03e-1)" "unprognostic (6.52e-3)" "unprognostic (1.31e-2)" "prognostic unfavorable (7.02e-7)" "unprognostic (3.08e-2)" "unprognostic (1.89e-1)" "unprognostic (1.23e-3)" "prognostic favorable (2.23e-4)" 6.8 7.2 5.9 7.8 6.1 3.1 7.7 6.0 8.2 7.1 6.9 6.8 4.2 9.0 7.8 5.6 6.0 4.7 5.9 5.9 7.2 5.7 6.6 5.6 10.8 6.6 6.5 5.5 7.9 9.5 4.9 8.2 6.6 5.4 7.2 4.2 4.6 11.6 3.2 10.0 7.8 10.4 6.1 9.0 5.4 2.5 7.2 9.7 5.6 3.4 10.8 8.5 6.3 6.7 10.8 7.1 11.7 13.1 29.5 16.8 8.6 16.7 16.7 12.3 18.4 11.5 6.9 16.5 22.2 21.4 10.6 11.9 15.9 16.8 20.4 14.4 10.6 19.3 11.1 12.9 19.1 21.3 21.7 17.5 9.6 13.3 18.0 15.7 15.5 11.2 10.5 19.7 13.9 10.9 12.5 20.7 12.4 18.6 13.8 12.2 12.2 24.0 11.6 13.9 12.7 20.0 8.1 4.9 13.4 11.7 13.2 17.8 19.7 13.1 8.0 3.8 8.9 27.1 25.2 21.7 11.1 20.6 18.8 2.9 16.4 13.9 16.2 15.7 18.7 13.9 18.2 17.0 20.7 10.1 21.1 20.0 1.2 29.5 10.8 11.5 22.3 15.0 5.9 6.1 6.0 8.2 5.9 7.2 6.6 6.5 6.6 6.1 7.2 6.7 19.1 0.0 6.2 11.4 15.7 16.8 7.3 17.4 16.5 13.6 9.7 8.5 5.2 14.3 10.1 20.2 6.2 10.6 17.1 5.2 0.0 6.9 0.7 5.5 19.3 16.1 9.5 8.4 32.7 5.3 14.7 14.5 9.2 7.0 17.7 11.3 13.6 12.5 8.4 5.0 31.6 11.7 22.4 11.9 81.2 0.2 8.7 16.6 12.4 6.5 151.4 10.3 21.6 23.6 25.8 5.0 8.3 17.0 14.1 8.0 8.5 6.0 6.5 13.0 13.1 16.7 13.4 1.5 1.5 13.9 14.9 6.6 15.5 17.4 13.9 5.9 PREB SEC12 ENSG00000138073 "Prolactin regulatory element binding" Q9HCU5 2 27130756-27134666 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "ER-Golgi transport, Protein transport, Transcription, Transcription regulation, Transport" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 101.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 369.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013582, HPA014133" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "HPA013582: AB_1855694, HPA014133: AB_1855695" "unprognostic (2.32e-1)" "unprognostic (2.11e-1)" "unprognostic (2.66e-2)" "unprognostic (1.61e-1)" "unprognostic (2.01e-2)" "unprognostic (1.21e-2)" "unprognostic (4.96e-3)" "unprognostic (1.44e-1)" "unprognostic (9.89e-2)" "unprognostic (1.21e-3)" "unprognostic (1.24e-2)" "unprognostic (2.69e-1)" "unprognostic (2.33e-3)" "unprognostic (5.13e-2)" "unprognostic (4.14e-2)" "unprognostic (5.25e-2)" "unprognostic (1.28e-2)" 45.2 46.0 40.0 28.6 41.4 16.5 39.5 41.5 47.9 38.7 37.3 34.0 27.7 57.3 104.8 41.0 46.1 25.9 62.5 42.0 42.6 49.0 137.2 33.4 33.3 44.2 41.4 49.9 73.9 30.8 42.8 22.6 41.4 42.7 27.7 16.7 60.0 34.6 134.5 29.6 36.0 40.7 41.8 51.5 42.5 35.1 42.1 31.0 30.3 112.0 38.3 34.9 32.3 42.6 63.5 62.2 35.4 56.5 84.8 30.2 65.8 44.6 46.5 63.5 44.4 59.1 38.7 78.3 45.9 44.5 68.7 35.3 70.3 56.3 41.3 58.7 63.2 64.2 30.7 128.3 111.1 74.3 58.2 28.8 67.5 60.2 68.2 34.2 44.7 61.4 48.0 68.3 57.6 73.4 69.2 56.5 37.2 81.5 64.8 63.9 70.9 369.2 46.9 33.2 79.8 42.8 42.8 88.3 65.7 36.1 39.4 125.3 25.0 33.9 48.7 29.8 51.0 150.5 67.9 95.1 56.4 83.4 65.4 73.7 61.0 103.3 50.4 52.2 53.7 44.5 42.1 50.2 62.5 43.9 40.1 41.7 25.4 65.0 55.8 74.1 50.9 63.9 40.0 41.4 41.5 47.9 42.0 42.6 44.2 41.4 41.4 41.8 42.1 42.6 9.7 16.0 12.7 5.5 33.5 18.0 9.8 14.3 9.1 12.2 21.8 19.0 14.2 20.0 10.6 20.2 12.5 45.3 22.8 17.3 35.2 29.8 5.9 5.8 14.7 10.8 8.4 30.7 7.4 35.1 60.3 18.2 28.1 11.9 23.6 13.1 16.1 36.1 38.0 6.7 7.7 28.5 20.3 19.8 16.3 9.1 23.6 17.9 19.6 8.4 16.6 25.3 24.7 9.5 9.1 30.9 20.4 44.8 101.5 18.4 30.0 29.2 3.8 10.9 32.9 10.2 21.0 32.1 44.8 18.7 17.3 77.4 22.6 16.2 22.3 12.9 PRELP "prolargin, SLRR2A" ENSG00000188783 "Proline and arginine rich end leucine rich repeat protein" P51888 1 203475806-203491352 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Fibroblasts: 206.6;Leydig cells: 100.6;Melanocytes: 192.1;Muller glia cells: 152.4;Peritubular cells: 199.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.1" "Group enriched" "Detected in some" 5 "ASC diff: 18.0;BJ: 7.7;fHDF/TERT166: 11.7;SuSa: 5.2" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 82.4" HPA059225 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 450000 "Cluster 17: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA059225: " "unprognostic (1.98e-1)" "unprognostic (7.74e-2)" "prognostic unfavorable (9.70e-5)" "unprognostic (2.83e-2)" "unprognostic (6.56e-2)" "unprognostic (2.75e-2)" "unprognostic (1.61e-1)" "unprognostic (2.84e-2)" "unprognostic (3.98e-2)" "unprognostic (2.04e-1)" "unprognostic (2.80e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (5.62e-6)" "unprognostic (2.81e-2)" "unprognostic (1.13e-1)" "unprognostic (1.42e-1)" "prognostic unfavorable (1.02e-4)" 114.8 23.4 12.6 4.2 14.2 0.5 77.5 7.7 20.2 126.7 20.0 136.4 6.6 147.7 7.6 41.3 108.6 40.4 212.0 11.6 10.0 25.3 15.6 124.7 8.0 10.2 8.2 128.2 13.1 2.5 22.6 12.0 9.4 73.6 8.9 21.5 32.7 77.1 35.6 56.4 61.0 51.4 8.3 44.2 41.3 7.2 10.3 3.2 60.4 36.9 15.9 147.8 92.9 9.4 0.2 0.2 0.5 0.1 18.0 0.5 0.4 7.7 1.0 0.2 0.2 0.0 0.1 1.2 0.6 11.7 0.1 0.6 0.2 0.3 0.3 0.0 0.1 0.2 0.5 0.2 0.0 0.3 0.1 0.0 0.0 0.1 0.2 2.1 0.0 0.4 0.2 0.4 1.3 0.1 0.1 0.5 0.4 0.3 0.1 0.4 0.2 0.4 0.0 0.3 1.0 0.2 0.2 0.2 0.8 5.2 0.2 0.1 0.6 0.5 0.2 0.3 0.1 0.2 0.3 1.2 0.1 0.2 0.5 1.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.4 0.2 0.1 0.1 0.1 0.0 12.6 14.2 7.7 20.2 11.6 10.0 10.2 8.2 9.4 8.3 10.3 9.4 8.8 0.0 5.8 5.2 0.9 18.2 1.0 0.0 2.2 3.6 4.2 5.1 7.4 1.5 0.6 0.0 2.1 0.1 0.3 0.1 0.0 0.0 1.1 0.6 1.7 15.6 0.0 2.7 1.6 0.0 0.1 206.6 4.6 1.6 5.1 0.2 22.9 0.3 0.3 1.7 0.2 0.0 0.0 0.3 19.2 5.3 100.6 0.9 192.1 22.5 0.0 152.4 0.0 7.5 0.5 0.0 0.0 199.7 0.4 0.6 0.0 0.1 1.5 8.9 26.3 9.6 38.3 3.1 2.4 1.6 9.9 0.3 1.6 0.1 0.0 1.3 PREX2 "DEP.2, DEPDC2, FLJ12987, P-REX2, PPP1R129" ENSG00000046889 "Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2" Q70Z35 8 67952046-68237032 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.1" "Cell type enhanced" "Detected in many" "Astrocytes: 717.6;Microglial cells: 120.9;Oligodendrocyte precursor cells: 422.2;Oligodendrocytes: 222.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 14.0;HUVEC TERT2: 19.2;JURKAT: 8.3;NTERA-2: 12.1;RH-30: 5.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015234, HPA075956" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "Endoplasmic reticulum" "HPA015234: AB_1847604, HPA075956: AB_2686769" "unprognostic (2.25e-1)" "unprognostic (3.32e-2)" "unprognostic (1.30e-2)" "unprognostic (3.39e-2)" "unprognostic (1.79e-1)" "unprognostic (2.37e-2)" "unprognostic (4.19e-1)" "unprognostic (8.27e-2)" "unprognostic (2.00e-1)" "unprognostic (1.98e-2)" "unprognostic (2.53e-2)" "unprognostic (8.77e-2)" "prognostic unfavorable (1.61e-7)" "unprognostic (8.30e-3)" "unprognostic (2.79e-1)" "unprognostic (3.67e-2)" "unprognostic (6.64e-2)" 9.3 1.0 11.5 1.2 15.2 0.1 5.5 15.8 9.4 4.4 0.1 2.6 1.7 2.5 1.7 1.7 5.5 3.2 3.8 12.5 10.1 1.6 1.2 4.4 0.8 16.1 13.5 1.9 1.1 1.1 1.9 8.1 13.2 2.5 1.7 3.6 1.3 2.2 2.2 1.7 1.8 2.5 12.6 1.3 1.6 0.9 13.4 0.9 7.3 5.0 1.0 2.7 2.6 14.1 0.0 0.0 14.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 8.3 0.0 0.0 0.0 0.0 3.0 0.0 12.1 0.0 0.0 0.0 5.5 0.0 0.7 0.0 3.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.3 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 15.2 15.8 9.4 12.5 10.1 16.1 13.5 13.2 12.6 13.4 14.1 103.3 3.2 5.0 717.6 0.3 4.0 3.6 0.0 0.0 21.8 0.6 0.8 6.1 1.5 3.1 1.8 2.1 0.0 0.6 0.0 0.0 0.2 52.7 15.2 3.2 57.0 0.0 0.0 2.2 0.0 0.0 19.7 0.0 26.2 1.3 0.0 56.4 0.7 0.1 5.0 81.3 0.0 0.0 2.7 5.1 9.6 11.1 0.8 8.8 120.9 0.0 65.8 0.0 422.2 222.1 0.0 0.0 10.5 1.3 0.8 0.0 0.0 0.7 4.1 26.3 3.9 13.8 0.9 1.2 0.5 2.6 0.0 1.1 0.2 0.0 1.6 PRKCSH "G19P1, GIIB, PCLD, PLD1, VASAP-60" ENSG00000130175 "Protein kinase C substrate 80K-H" P14314 19 11435284-11450968 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004465, HPA041940, HPA043560" Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA 55000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 50: Non-specific - Ribosome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum" "CAB004465: AB_626622, HPA041940: AB_2677758, HPA043560: AB_2678553" "unprognostic (2.75e-1)" "unprognostic (1.67e-1)" "unprognostic (2.45e-2)" "unprognostic (2.14e-1)" "unprognostic (5.65e-2)" "unprognostic (2.63e-2)" "unprognostic (2.52e-2)" "unprognostic (5.52e-2)" "unprognostic (1.16e-1)" "unprognostic (2.07e-3)" "unprognostic (1.28e-2)" "unprognostic (3.15e-2)" "prognostic unfavorable (7.69e-4)" "unprognostic (1.63e-3)" "unprognostic (2.10e-1)" "unprognostic (3.44e-1)" "unprognostic (1.18e-1)" 115.3 107.6 76.4 81.2 86.7 169.6 117.6 85.1 97.6 144.0 91.4 119.7 120.0 123.0 113.0 106.5 126.2 92.0 90.4 76.4 82.0 108.8 159.9 105.5 93.3 89.9 83.9 196.9 186.2 116.3 118.3 108.8 85.9 108.5 98.9 46.6 145.9 97.8 74.8 129.3 121.7 78.5 79.6 111.2 124.9 88.5 83.3 83.9 135.5 44.9 86.2 109.9 122.6 88.8 274.8 216.7 211.6 391.5 351.2 426.4 241.5 305.5 387.6 331.5 302.7 328.3 327.5 204.4 478.1 409.2 165.4 283.4 226.3 309.6 292.1 193.3 173.5 178.0 269.4 268.8 258.0 263.0 236.4 404.5 228.6 312.5 261.4 425.6 232.8 210.1 204.8 422.4 289.0 470.1 187.9 322.1 485.0 129.7 283.3 201.8 215.3 505.6 223.2 260.1 146.9 291.5 282.3 280.4 280.5 200.8 292.5 296.7 263.6 437.1 198.2 416.0 361.0 471.9 575.3 132.3 330.1 276.8 306.5 38.8 47.2 45.1 37.9 36.2 42.6 35.9 31.8 36.4 36.1 38.7 30.2 33.1 56.3 32.8 41.2 75.7 37.5 39.5 76.4 86.7 85.1 97.6 76.4 82.0 89.9 83.9 85.9 79.6 83.3 88.8 45.2 12.8 16.9 15.3 65.1 41.8 72.2 90.0 39.9 18.2 56.9 47.5 10.5 71.4 44.9 64.4 33.3 174.9 54.6 152.0 33.2 88.7 18.1 47.4 65.0 52.0 58.8 40.6 12.3 127.5 189.1 62.6 70.3 67.2 41.9 104.5 60.3 86.4 93.4 10.1 12.5 123.2 65.1 80.0 43.4 55.9 78.6 59.3 53.4 14.0 81.4 59.8 61.8 6.0 39.0 89.0 132.8 72.6 91.4 45.9 187.8 62.7 32.7 30.2 39.5 39.8 52.0 36.8 55.2 49.5 37.8 143.5 55.5 84.2 128.2 66.6 PRR11 FLJ11029 ENSG00000068489 "Proline rich 11" Q96HE9 17 59155732-59206709 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 18.1;lymphoid tissue: 20.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 26.3;Extravillous trophoblasts: 22.3;Granulosa cells: 14.4;Kupffer cells: 18.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 9.5" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA023923, HPA052376" Uncertain Approved "Endoplasmic reticulum" Yes Yes "Cluster 14: Monocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Endoplasmic reticulum" "HPA023923: AB_1855783, HPA052376: AB_2681803" "unprognostic (1.74e-2)" "unprognostic (1.02e-1)" "unprognostic (1.30e-2)" "prognostic unfavorable (1.90e-4)" "unprognostic (2.15e-1)" "unprognostic (3.03e-2)" "prognostic unfavorable (1.35e-7)" "prognostic unfavorable (1.79e-4)" "unprognostic (7.22e-3)" "unprognostic (2.00e-2)" "prognostic unfavorable (6.18e-4)" "unprognostic (2.80e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.56e-2)" "unprognostic (5.21e-2)" "unprognostic (1.84e-1)" "unprognostic (1.55e-3)" 1.3 0.7 1.8 6.5 2.0 18.1 1.8 4.3 2.7 1.2 1.1 4.6 6.5 1.7 0.5 3.8 1.4 1.4 1.0 2.0 1.3 0.6 1.4 2.3 10.3 2.3 1.5 1.4 0.5 0.3 0.0 4.3 2.2 0.8 5.6 1.7 0.6 0.7 1.2 3.1 5.0 3.6 1.1 3.3 2.4 1.8 2.3 20.6 1.3 0.4 12.0 2.0 0.6 3.7 105.3 56.9 84.5 24.8 2.4 16.0 31.7 66.7 41.9 69.1 54.2 68.4 78.7 80.2 65.9 52.7 56.2 40.7 67.0 73.9 145.0 99.3 39.1 86.4 58.8 50.3 0.6 88.7 32.5 4.0 5.3 81.9 109.0 17.1 77.2 57.9 48.6 76.7 72.8 95.2 80.7 26.1 31.9 52.0 82.5 67.3 135.7 45.9 20.0 32.4 34.5 45.4 61.7 18.4 29.2 38.0 54.4 34.1 57.8 146.4 157.3 73.5 117.8 48.8 108.2 73.6 34.5 47.4 150.1 1.7 2.1 2.3 0.6 4.0 0.2 1.1 0.5 0.7 2.6 0.6 0.3 0.5 2.1 0.5 9.5 1.1 1.4 0.8 1.8 2.0 4.3 2.7 2.0 1.3 2.3 1.5 2.2 1.1 2.3 3.7 4.5 0.0 1.7 3.3 3.1 1.9 2.0 1.5 0.0 2.0 0.8 1.5 2.0 1.5 1.6 0.0 0.0 6.2 1.4 2.0 0.0 0.4 0.9 1.4 1.9 3.6 4.9 26.3 1.6 0.5 22.3 2.9 2.6 2.2 2.5 14.4 4.2 0.3 7.8 1.7 1.8 5.0 0.0 18.6 6.3 0.4 0.9 7.8 1.8 2.8 8.4 0.9 4.1 2.0 3.4 0.9 0.7 2.2 9.7 1.1 0.5 0.5 0.6 3.2 0.0 2.9 3.3 2.6 5.1 5.5 1.3 2.1 3.3 1.3 8.4 1.7 PTGES "MGST-IV, MGST1-L1, MGST1L1, PIG12, TP53I12" ENSG00000148344 "Prostaglandin E synthase" O14684 9 129738331-129753042 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Isomerase, Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 84.2;urinary bladder: 78.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 101.2;Cytotrophoblasts: 146.0;Extravillous trophoblasts: 293.1;Syncytiotrophoblasts: 276.2" "Cancer enhanced" "Detected in all" "urothelial cancer: 69.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "basophil: 28.9" "Lineage enriched" "Detected in many" 7 "granulocytes: 28.9" "Cell line enhanced" "Detected in many" "ASC diff: 147.7;BEWO: 162.7;GAMG: 292.8;HaCaT: 216.3;SK-BR-3: 157.6;U-2197: 404.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045064 Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "Endoplasmic reticulum" "HPA045064: AB_10795889" "unprognostic (2.92e-3)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.32e-4)" "unprognostic (2.54e-2)" "unprognostic (1.94e-3)" "unprognostic (1.25e-1)" "unprognostic (5.38e-3)" "unprognostic (1.24e-3)" "unprognostic (2.92e-1)" "unprognostic (1.61e-1)" "prognostic unfavorable (7.97e-5)" "unprognostic (2.22e-1)" "unprognostic (4.66e-2)" "unprognostic (9.78e-3)" "unprognostic (3.19e-2)" "unprognostic (1.30e-1)" "unprognostic (5.20e-2)" 36.7 1.4 4.1 13.9 3.6 7.8 25.5 3.9 4.5 26.1 3.5 9.2 2.8 3.7 19.0 17.8 5.4 9.0 8.5 4.5 5.1 8.1 0.7 7.8 7.6 6.1 5.8 2.2 1.6 42.1 1.9 58.4 7.1 13.7 4.2 0.0 30.8 84.2 1.3 42.3 9.1 4.1 4.1 2.5 7.1 16.9 4.7 4.2 3.7 1.1 30.7 78.6 20.0 3.5 1.5 94.9 0.1 46.6 147.7 51.9 162.7 7.4 64.2 1.1 1.7 5.6 71.7 0.1 2.7 18.0 292.8 216.3 0.7 7.2 0.6 0.3 0.5 0.0 62.5 0.4 3.5 0.0 0.0 30.9 49.0 0.9 0.3 1.4 0.0 0.9 0.0 0.1 0.7 1.7 0.2 0.0 1.2 46.7 8.2 0.2 0.0 0.3 5.3 102.2 0.8 3.6 87.1 157.6 0.8 6.3 83.3 0.0 0.5 0.1 0.4 404.8 0.0 0.0 0.0 0.0 78.8 0.1 0.7 28.9 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 4.0 0.0 0.0 0.3 4.1 3.6 3.9 4.5 4.5 5.1 6.1 5.8 7.1 4.1 4.7 3.5 3.4 0.0 0.0 0.3 0.3 17.8 8.9 101.2 10.8 0.0 29.7 19.7 0.1 0.0 53.2 3.7 0.0 146.0 0.6 0.0 1.9 13.4 0.6 1.6 2.3 4.0 7.3 0.0 1.0 1.1 293.1 70.7 0.0 5.0 1.3 61.5 0.0 0.0 17.5 0.0 2.8 6.6 30.5 0.0 21.6 0.4 0.3 13.2 14.2 7.5 7.2 0.0 0.0 0.0 0.2 8.1 0.2 0.0 0.3 8.2 0.3 0.5 6.7 0.0 0.0 0.8 13.5 0.3 0.0 5.5 43.0 276.2 0.8 0.2 0.4 49.2 PTGIS "CYP8A1, PGIS" ENSG00000124212 "Prostaglandin I2 synthase" Q16647 20 49503874-49568137 "Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Isomerase, Lyase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 80.7;urinary bladder: 81.7" "Cell type enhanced" "Detected in many" "Endothelial cells: 28.1;Fibroblasts: 70.8;Hepatic stellate cells: 117.8;Leydig cells: 26.8;Peritubular cells: 104.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 45.1;ASC TERT1: 45.2;U-2197: 143.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB009517, HPA014193, HPA052244" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB009517: AB_2173209, HPA014193: AB_1855746, HPA052244: AB_2732574" "unprognostic (7.68e-2)" "unprognostic (1.90e-1)" "unprognostic (5.09e-3)" "unprognostic (1.38e-2)" "unprognostic (1.80e-2)" "unprognostic (1.74e-1)" "unprognostic (1.21e-2)" "unprognostic (1.29e-2)" "unprognostic (1.25e-1)" "unprognostic (4.02e-2)" "unprognostic (2.45e-2)" "unprognostic (5.22e-2)" "prognostic unfavorable (4.74e-8)" "unprognostic (2.29e-2)" "unprognostic (7.61e-2)" "unprognostic (4.89e-3)" "prognostic unfavorable (9.99e-5)" 43.2 4.7 0.7 9.0 2.5 0.3 24.0 0.3 1.9 29.5 1.8 38.9 3.2 79.0 16.1 16.5 80.7 31.3 40.4 0.5 0.8 4.0 6.0 18.2 0.7 0.6 0.4 38.1 2.5 0.3 0.9 1.1 0.4 22.2 6.6 0.2 7.6 8.3 4.0 7.2 10.5 40.5 0.6 0.5 17.9 5.1 1.0 0.3 7.8 2.4 0.8 81.7 18.2 0.6 0.0 0.1 1.9 0.1 45.1 45.2 0.5 1.0 5.7 0.2 0.0 0.0 0.0 0.1 18.4 13.7 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 5.6 0.0 0.1 3.3 0.0 0.6 0.0 15.1 0.7 0.0 0.0 0.1 0.1 0.0 0.1 0.2 8.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.4 0.4 0.1 0.2 0.0 8.2 0.1 0.0 0.0 0.8 2.4 143.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.7 2.5 0.3 1.9 0.5 0.8 0.6 0.4 0.4 0.6 1.0 0.6 5.3 3.2 2.7 0.0 0.0 3.7 0.7 0.0 0.0 1.1 2.2 1.3 5.0 2.8 1.9 3.7 0.0 0.3 0.3 0.0 0.0 0.6 1.8 0.0 0.9 28.1 0.0 2.7 2.7 0.0 0.2 70.8 1.5 0.1 0.0 25.0 117.8 1.0 0.3 0.0 2.4 0.0 0.0 3.1 6.7 3.3 26.8 1.0 1.8 6.5 0.1 0.4 0.0 1.0 0.2 1.2 0.0 104.9 0.3 0.4 0.0 0.2 2.2 4.5 0.0 7.9 3.5 0.7 1.4 0.5 4.8 0.3 1.0 0.5 0.0 0.6 PTN "HBGF8, HBNF, NEGF1" ENSG00000105894 Pleiotrophin P21246 7 137227341-137343774 "Cancer-related genes, Predicted secreted proteins" "Growth factor, Heparin-binding, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 280.4;parathyroid gland: 383.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 672.0;Extravillous trophoblasts: 416.0;Horizontal cells: 526.6;Muller glia cells: 548.5;Oligodendrocyte precursor cells: 322.7;Squamous epithelial cells: 439.9" "Cancer enriched" "Detected in all" 11 "glioma: 514.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 12 "AF22: 1717.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017685, HPA073913" Enhanced Supported "Endoplasmic reticulum" "Secreted to blood" NA NA 167000 1400000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 12: NES - Nervous system development" "Cluster 36: Stromal cells - Cell proliferation" "Endoplasmic reticulum" "CAB017685: AB_1128556, HPA073913: " "unprognostic (1.51e-2)" "unprognostic (7.87e-2)" "unprognostic (5.44e-2)" "unprognostic (4.23e-2)" "unprognostic (1.92e-1)" "unprognostic (7.19e-2)" "unprognostic (2.81e-2)" "unprognostic (7.29e-2)" "unprognostic (1.30e-1)" "unprognostic (1.09e-2)" "unprognostic (3.86e-1)" "unprognostic (1.22e-2)" "prognostic favorable (1.35e-4)" "unprognostic (2.34e-1)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" "unprognostic (1.16e-2)" 26.2 18.2 212.9 4.1 206.4 0.1 82.3 217.0 280.4 100.0 182.0 31.4 5.4 76.8 55.3 78.2 19.2 55.9 87.7 209.6 205.2 38.4 8.5 18.4 7.4 220.3 200.5 19.0 8.4 383.5 126.1 36.2 196.3 116.1 21.6 63.4 37.4 52.5 2.2 9.1 10.1 54.0 204.2 40.4 15.7 53.8 207.6 21.4 18.9 18.8 11.4 24.8 65.1 209.1 1.2 0.0 1717.6 21.2 0.4 0.9 140.6 45.3 134.3 25.1 34.3 0.4 0.2 0.0 0.2 60.0 15.6 1.0 0.0 0.0 18.9 0.0 1.4 0.0 0.0 0.0 7.7 0.0 0.5 1.9 0.0 16.6 0.2 24.6 0.0 0.0 0.0 8.2 7.0 0.0 0.0 0.6 133.5 0.0 1.1 0.1 2.8 0.4 0.7 0.0 8.0 116.5 0.0 0.0 0.2 24.1 0.2 0.2 0.0 37.4 32.9 1.8 99.4 0.7 0.0 0.0 119.7 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 212.9 206.4 217.0 280.4 209.6 205.2 220.3 200.5 196.3 204.2 207.6 209.1 10.1 0.0 0.0 303.3 1.3 23.2 1.7 85.0 209.5 27.7 244.6 117.3 14.6 2.8 20.9 1.8 6.2 220.0 2.2 0.0 9.8 1.1 24.5 53.4 672.0 32.0 0.0 0.0 4.9 0.0 416.0 248.8 0.5 24.6 0.0 1.1 7.1 0.3 20.4 526.6 18.1 0.0 0.0 0.3 20.6 14.0 172.7 4.0 44.4 102.1 0.0 548.5 0.0 322.7 218.4 0.3 0.0 185.5 2.5 18.6 0.0 7.5 7.2 32.3 59.2 3.0 91.4 4.0 2.4 439.9 13.9 193.3 4.4 144.7 0.0 2.2 PTPN1 PTP1B ENSG00000196396 "Protein tyrosine phosphatase non-receptor type 1" P18031 20 50510321-50585241 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 227.6;monocytes: 207.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009329, HPA012542, CAB015217" Approved Enhanced "Endoplasmic reticulum" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 65: Plasmacytoid DCs - Unknown function" "Endoplasmic reticulum" "CAB009329: AB_2174944, CAB015217: , HPA012542: AB_1855915" "unprognostic (1.67e-1)" "unprognostic (7.78e-2)" "unprognostic (1.48e-1)" "unprognostic (1.05e-2)" "unprognostic (1.14e-1)" "unprognostic (3.44e-2)" "unprognostic (2.98e-3)" "unprognostic (3.95e-2)" "unprognostic (2.40e-2)" "unprognostic (6.47e-3)" "unprognostic (5.87e-2)" "unprognostic (1.67e-1)" "unprognostic (1.66e-2)" "unprognostic (6.70e-2)" "unprognostic (2.99e-2)" "unprognostic (1.49e-1)" "unprognostic (2.58e-2)" 26.3 30.8 13.0 44.5 14.0 55.4 22.1 12.3 14.7 23.2 28.6 24.8 13.9 23.0 18.7 29.6 22.0 23.1 31.9 17.5 13.0 46.7 21.0 55.2 52.9 16.1 14.4 25.6 15.9 48.3 19.7 34.2 13.7 25.0 18.8 9.9 18.9 18.2 35.4 23.9 28.3 21.9 13.7 46.5 21.0 18.3 14.2 35.5 18.7 21.6 52.6 35.8 23.5 14.1 66.1 32.4 38.4 26.6 24.6 33.6 54.5 43.2 40.8 123.8 44.9 96.1 134.3 32.5 74.8 40.0 48.7 56.9 30.8 123.8 78.2 48.5 27.6 45.9 30.9 51.3 49.0 48.2 60.2 39.6 84.9 55.9 68.2 54.3 72.3 38.5 81.5 28.9 68.3 36.5 52.1 38.1 20.4 36.2 44.2 45.6 44.6 31.1 71.2 48.4 30.8 35.3 62.0 77.6 71.3 32.1 50.4 50.9 108.2 107.3 43.1 48.8 54.2 31.4 27.3 38.9 67.1 32.3 40.6 19.8 7.1 25.2 12.9 12.1 9.5 19.2 10.8 10.0 7.1 17.4 8.9 9.8 15.4 5.3 22.8 11.8 9.4 8.7 13.0 14.0 12.3 14.7 17.5 13.0 16.1 14.4 13.7 13.7 14.2 14.1 34.0 227.6 83.6 22.9 147.8 86.0 61.7 37.1 56.3 25.1 23.9 24.4 30.0 11.5 40.0 36.8 47.9 54.0 68.7 26.1 23.5 26.2 67.7 45.0 44.0 36.3 18.6 32.0 61.6 19.3 20.9 52.1 32.1 65.9 70.8 14.2 41.4 20.8 37.4 43.7 43.3 16.4 20.3 40.6 169.5 37.4 14.0 100.7 37.4 32.8 207.8 12.1 38.1 27.6 42.1 41.7 14.5 12.0 178.7 26.6 8.9 65.2 30.2 27.5 19.7 55.5 57.7 20.8 24.5 48.7 47.2 54.3 83.8 44.3 14.6 53.5 PTPN5 "PTPSTEP, STEP, STEP61" ENSG00000110786 "Protein tyrosine phosphatase non-receptor type 5" P54829 11 18727928-18792721 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "brain: 161.0" "Group enriched" "Detected in some" 4 "Excitatory neurons: 59.0;Inhibitory neurons: 51.9" "Group enriched" "Detected in some" 6 "glioma: 1.6;testis cancer: 2.0" "Region enhanced" "Detected in many" "basal ganglia: 161.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 1.1;NTERA-2: 1.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031014, HPA072091" Supported Approved "Endoplasmic reticulum" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "HPA031014: AB_10669550, HPA072091: AB_2686487" "unprognostic (1.23e-1)" "unprognostic (2.91e-2)" "unprognostic (8.93e-3)" "unprognostic (1.09e-2)" "unprognostic (3.27e-2)" "unprognostic (2.13e-2)" "unprognostic (5.83e-3)" "unprognostic (3.59e-1)" "unprognostic (4.91e-2)" "unprognostic (2.59e-1)" "unprognostic (2.00e-1)" "unprognostic (3.58e-1)" "unprognostic (8.44e-4)" "unprognostic (4.21e-3)" "unprognostic (3.90e-2)" "unprognostic (9.39e-2)" "unprognostic (8.49e-2)" 1.5 0.5 37.2 0.2 161.0 0.1 1.1 0.0 55.2 0.7 0.0 1.0 0.1 0.8 0.0 0.5 1.1 0.3 11.9 32.1 25.5 1.7 0.0 1.5 0.1 11.3 6.4 2.1 0.4 0.2 2.1 0.0 6.7 1.0 0.3 2.0 1.2 0.6 0.7 0.6 0.6 0.4 4.7 0.4 0.9 2.9 19.9 0.0 0.7 3.3 0.0 1.0 1.1 29.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.2 161.0 0.0 55.2 32.1 25.5 11.3 6.4 6.7 4.7 19.9 29.5 0.1 0.0 0.0 4.2 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.0 0.2 6.9 0.0 0.0 59.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 51.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.5 0.0 0.3 0.0 12.5 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 2.7 0.1 0.0 0.0 0.0 0.2 0.0 0.0 PTPRN "IA-2, ICA512" ENSG00000054356 "Protein tyrosine phosphatase receptor type N" Q16849 2 219289623-219309648 "Disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" Receptor "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 234.3;pituitary gland: 182.3" "Group enriched" "Detected in some" 9 "Bipolar cells: 59.0;Cone photoreceptor cells: 60.5;Enteroendocrine cells: 47.1;Excitatory neurons: 44.6;Horizontal cells: 97.6;Inhibitory neurons: 48.1;Rod photoreceptor cells: 38.4" "Group enriched" "Detected in some" 12 "glioma: 5.3;pancreatic cancer: 18.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "U-2 OS: 66.4;U-87 MG: 249.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007152, HPA007179" Enhanced Approved "Endoplasmic reticulum" NA NA 38000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 62: Horizontal cells - Visual perception" "Endoplasmic reticulum" "HPA007152: AB_2667759, HPA007179: AB_1079714" "unprognostic (1.43e-1)" "unprognostic (1.33e-4)" "unprognostic (2.91e-3)" "unprognostic (5.83e-3)" "prognostic unfavorable (1.45e-7)" "unprognostic (3.64e-2)" "unprognostic (1.24e-4)" "unprognostic (1.58e-3)" "unprognostic (1.02e-1)" "unprognostic (6.20e-4)" "unprognostic (1.44e-2)" "unprognostic (1.54e-1)" "unprognostic (2.28e-10)" "unprognostic (1.43e-2)" "unprognostic (2.49e-1)" "unprognostic (1.10e-2)" "unprognostic (8.61e-2)" 0.7 25.2 91.6 4.8 98.3 0.6 0.2 12.2 139.0 0.2 0.0 5.3 1.6 0.3 0.0 0.3 0.1 0.3 0.3 116.6 234.3 0.3 0.2 0.2 0.1 62.4 85.5 0.2 36.3 0.0 182.3 0.2 138.1 0.4 0.8 21.4 0.1 0.0 0.1 0.9 2.0 1.6 22.2 0.1 6.0 0.7 98.9 0.0 0.4 0.0 0.0 0.9 0.9 70.1 0.1 0.0 0.1 0.0 0.0 0.0 0.2 2.5 0.0 0.8 0.0 0.1 0.0 0.0 1.2 4.6 6.8 0.4 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.8 1.9 0.0 0.6 8.4 0.0 20.8 0.0 0.2 0.0 0.0 0.4 0.5 1.5 0.0 0.1 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.6 10.8 0.0 0.0 0.0 9.0 0.0 0.1 0.0 0.1 66.4 0.0 0.2 0.1 0.3 1.1 249.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 91.6 98.3 12.2 139.0 116.6 234.3 62.4 85.5 138.1 22.2 98.9 70.1 0.0 0.0 0.0 5.5 0.1 0.1 0.1 0.1 0.0 59.0 0.1 0.1 2.0 0.0 0.0 0.0 60.5 0.0 0.1 0.1 1.9 0.1 0.3 0.1 0.2 0.7 47.1 2.7 44.6 0.0 0.3 1.9 2.6 0.0 0.0 0.0 0.0 0.3 0.1 97.6 48.1 0.7 2.0 0.0 0.4 0.8 0.3 1.8 1.8 4.7 0.0 6.0 0.0 1.5 4.0 2.7 0.0 0.0 0.1 0.2 0.0 0.1 0.0 38.4 0.0 0.1 1.9 4.2 2.7 0.0 0.1 0.0 0.1 0.0 0.1 0.2 RAB42 MGC45806 ENSG00000188060 "RAB42, member RAS oncogene family" Q8N4Z0 1 28592200-28595449 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 24.5" "Cell type enriched" "Detected in many" 7 "Hofbauer cells: 91.3" "Cancer enhanced" "Detected in many" "renal cancer: 10.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 10.0;Hep G2: 14.3;HSkMC: 8.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050290 Approved "Endoplasmic reticulum" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 4: Macrophages - Innate immune response" "Endoplasmic reticulum" "HPA050290: AB_2681075" "unprognostic (1.10e-1)" "unprognostic (2.56e-1)" "unprognostic (1.72e-1)" "unprognostic (1.00e-1)" "unprognostic (8.25e-2)" "unprognostic (7.59e-2)" "unprognostic (2.00e-4)" "unprognostic (8.81e-2)" "unprognostic (2.39e-1)" "unprognostic (4.09e-2)" "unprognostic (1.34e-2)" "unprognostic (2.82e-2)" "unprognostic (1.52e-2)" "unprognostic (8.77e-2)" "unprognostic (3.02e-2)" "unprognostic (8.83e-2)" "unprognostic (2.07e-3)" 3.0 0.7 0.9 1.7 1.1 0.8 2.2 1.5 2.9 2.2 1.5 2.1 1.4 1.7 0.6 0.7 1.0 1.7 0.9 0.9 0.8 0.9 1.2 2.8 6.6 1.9 1.3 0.4 0.5 2.7 0.3 4.5 1.6 0.7 2.3 0.9 2.6 0.6 0.3 0.6 1.6 1.5 1.1 3.5 1.3 1.4 2.3 24.5 0.6 0.6 3.6 1.9 1.1 3.9 0.1 0.7 0.9 0.0 4.1 10.0 0.0 0.4 3.8 4.1 5.3 2.0 1.5 0.2 2.0 4.3 0.4 0.2 4.1 0.0 2.7 0.1 0.0 0.3 6.8 14.3 1.7 1.1 0.0 8.8 0.1 2.2 0.0 0.4 1.2 0.1 0.1 0.1 0.9 0.0 0.1 2.2 4.8 0.0 0.0 6.5 0.0 1.7 1.8 0.0 0.3 1.5 3.7 0.1 0.0 0.6 0.2 1.8 0.4 0.0 1.2 3.9 0.0 0.3 2.1 0.2 0.1 3.9 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.9 1.1 1.5 2.9 0.9 0.8 1.9 1.3 1.6 1.1 2.3 3.9 0.5 0.0 0.0 0.0 0.7 0.1 0.2 0.7 0.0 0.5 1.2 1.0 0.4 1.5 1.0 0.0 0.0 0.6 0.1 0.2 0.0 8.5 5.3 3.4 3.9 0.3 0.0 0.4 0.1 0.0 0.8 3.4 0.0 3.2 0.0 0.5 2.5 0.0 91.3 0.0 0.1 0.1 0.0 3.5 1.7 12.2 1.5 11.7 0.0 1.0 1.1 1.0 0.0 0.0 0.1 2.9 1.2 0.0 1.2 0.2 0.3 0.5 0.4 0.9 0.0 4.5 0.9 2.5 1.8 0.4 0.4 0.4 0.3 0.2 0.1 0.1 RABL3 MGC23920 ENSG00000144840 "RAB, member of RAS oncogene family like 3" Q5HYI8 3 120684938-120742993 "Disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 116.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035150, HPA035151, HPA069861" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 9: Photoreceptor cells - Phototransduction" "Endoplasmic reticulum" "HPA035150: AB_2674493, HPA035151: AB_10601154, HPA069861: " "unprognostic (1.69e-2)" "unprognostic (5.10e-2)" "unprognostic (8.32e-2)" "unprognostic (3.96e-2)" "unprognostic (1.88e-1)" "unprognostic (7.22e-2)" "unprognostic (1.37e-1)" "unprognostic (1.27e-1)" "unprognostic (7.19e-2)" "unprognostic (2.94e-1)" "unprognostic (2.11e-3)" "unprognostic (2.78e-1)" "prognostic favorable (2.79e-5)" "unprognostic (2.33e-1)" "unprognostic (6.15e-2)" "unprognostic (8.44e-3)" "unprognostic (3.65e-1)" 10.8 16.1 2.3 5.6 2.5 5.3 8.8 2.6 4.1 7.0 2.6 8.1 5.5 7.0 2.7 7.9 5.9 5.7 7.3 2.1 3.1 9.8 9.7 5.6 5.9 3.0 2.8 9.2 6.4 11.8 6.3 6.9 2.9 6.9 8.6 5.8 6.9 6.5 13.8 6.3 6.0 6.2 2.7 5.6 7.1 4.2 2.4 6.4 12.3 11.9 7.3 7.3 7.9 3.7 20.6 17.8 12.6 3.9 11.7 17.0 11.4 18.8 13.8 10.0 8.3 12.6 6.5 17.3 8.5 15.4 17.6 7.1 14.0 9.2 18.3 14.8 5.9 16.0 12.9 15.7 8.1 31.2 9.1 8.4 11.2 8.9 10.7 11.6 15.1 9.4 14.2 9.7 12.8 20.8 18.2 3.0 6.4 19.9 8.6 7.7 17.4 6.6 9.6 10.0 5.8 4.5 9.2 5.5 5.4 4.8 10.5 9.8 22.1 6.5 7.5 4.8 17.1 5.4 7.9 13.6 16.7 25.4 8.4 3.7 3.6 2.6 4.6 5.6 3.6 3.2 4.5 5.1 6.5 2.6 3.8 4.4 3.7 5.6 3.1 3.4 5.3 3.4 2.3 2.5 2.6 4.1 2.1 3.1 3.0 2.8 2.9 2.7 2.4 3.7 17.6 9.6 11.7 14.7 11.6 6.4 17.2 17.3 11.4 39.8 13.7 10.0 14.3 12.8 16.7 9.2 116.7 13.3 7.7 13.1 7.9 15.2 25.5 22.3 11.9 12.8 5.4 10.7 11.7 16.2 18.0 13.8 9.7 14.2 8.2 10.4 8.2 18.1 14.7 8.4 10.2 12.7 16.2 10.6 7.2 9.8 5.9 12.0 10.6 2.8 11.4 19.2 9.2 7.5 17.1 14.6 15.8 6.0 11.3 12.2 9.6 26.4 15.7 20.0 0.0 16.5 10.4 26.9 8.5 10.5 11.1 22.0 10.0 16.6 12.1 15.4 RASGRF2 "GRF2, Ras-GRF2" ENSG00000113319 "Ras protein specific guanine nucleotide releasing factor 2" O14827 5 80960363-81230162 "Predicted intracellular proteins, RAS pathway related proteins" "Calmodulin-binding, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 22.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 220.6;Inhibitory neurons: 407.6;Microglial cells: 89.0;Oligodendrocytes: 395.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 1.9;MAIT T-cell: 5.2;memory CD4 T-cell: 2.6;memory CD8 T-cell: 1.5;naive CD4 T-cell: 4.2;naive CD8 T-cell: 3.0" "Lineage enriched" "Detected in single" 52 "T-cells: 5.2" "Cell line enhanced" "Detected in some" "BEWO: 37.8;CACO-2: 23.3;Hep G2: 31.8;HHSteC: 20.8;hTERT-RPE1: 15.3;SuSa: 16.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 4 "amygdala: 24.5;cerebral cortex: 77.3;hippocampal formation: 46.6;olfactory bulb: 27.0" HPA018679 Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 28: BEWO - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "HPA018679: AB_1856089" "unprognostic (1.32e-1)" "unprognostic (6.96e-2)" "unprognostic (7.27e-2)" "unprognostic (7.80e-2)" "unprognostic (3.62e-1)" "unprognostic (1.00e-1)" "unprognostic (5.76e-3)" "unprognostic (2.58e-1)" "unprognostic (4.02e-1)" "unprognostic (8.51e-2)" "unprognostic (8.13e-2)" "unprognostic (1.34e-1)" "unprognostic (1.47e-3)" "unprognostic (1.37e-3)" "unprognostic (2.13e-2)" "unprognostic (5.01e-2)" "unprognostic (1.12e-1)" 11.2 0.9 10.5 3.4 9.4 1.0 7.3 1.2 14.9 3.4 16.1 2.9 1.8 2.4 0.8 1.3 2.2 5.2 5.4 11.6 4.8 4.8 0.5 3.3 3.5 3.4 2.2 17.6 1.0 2.3 4.1 10.2 2.5 3.6 1.4 22.9 1.5 1.5 2.7 1.1 2.4 2.6 5.1 2.2 1.8 2.0 13.8 1.5 4.7 6.8 2.8 3.4 2.4 10.0 0.0 2.1 0.5 0.3 0.0 0.0 37.8 0.7 9.3 0.4 0.4 23.3 0.0 0.4 11.9 0.0 0.2 0.6 0.0 0.0 1.2 0.6 4.0 0.2 0.3 31.8 20.8 0.0 0.0 1.0 0.1 8.8 0.1 15.3 0.2 0.5 0.0 0.1 0.0 0.3 0.3 0.2 4.5 0.0 0.1 0.2 4.5 0.1 1.4 0.0 0.4 0.5 0.1 0.0 0.3 16.2 0.0 0.1 0.1 0.0 0.2 0.2 0.1 0.1 0.1 0.3 0.2 0.1 0.4 0.0 0.0 0.0 1.9 0.0 5.2 0.0 2.6 1.5 0.0 0.0 4.2 3.0 0.0 0.0 0.0 0.0 0.7 1.0 10.5 9.4 1.2 14.9 11.6 4.8 3.4 2.2 2.5 5.1 13.8 10.0 45.3 0.0 1.1 10.1 0.6 1.7 0.3 0.1 0.0 15.9 0.2 0.3 5.2 0.0 0.6 9.2 58.4 1.1 2.2 0.2 0.0 0.4 10.2 1.3 0.3 23.7 0.0 0.0 220.6 0.0 26.9 2.5 0.5 1.1 0.0 0.2 5.3 0.1 1.1 1.7 407.6 0.5 0.0 0.3 0.8 3.0 0.9 0.5 1.8 89.0 0.2 3.7 6.2 8.5 395.6 0.7 1.2 9.1 0.9 0.3 1.0 2.1 0.0 42.1 0.0 1.5 0.9 6.7 1.6 0.3 0.6 0.8 7.5 4.1 1.3 0.5 RCN1 "FLJ37041, PIG20, Rcal, RCN" ENSG00000049449 "Reticulocalbin 1" Q15293 11 32091074-32105722 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "epididymis: 660.2" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 288.2;Muller glia cells: 327.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA038474, HPA062104" Approved Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA 9400000 "Cluster 39: Non-specific - mRNA processing" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA038474: AB_10672595, HPA062104: AB_2684683" "unprognostic (1.65e-1)" "unprognostic (7.69e-3)" "unprognostic (1.24e-1)" "unprognostic (2.03e-2)" "unprognostic (7.20e-3)" "unprognostic (1.70e-2)" "unprognostic (6.92e-3)" "prognostic unfavorable (7.13e-6)" "unprognostic (8.85e-2)" "unprognostic (1.30e-2)" "unprognostic (2.12e-1)" "unprognostic (9.32e-2)" "prognostic unfavorable (2.70e-13)" "unprognostic (1.78e-2)" "unprognostic (2.04e-1)" "unprognostic (1.14e-1)" "unprognostic (6.93e-3)" 81.8 54.4 26.7 58.3 39.6 8.1 64.6 24.0 28.2 73.9 37.2 54.7 43.4 79.7 660.2 25.7 69.5 50.1 46.0 26.4 37.2 39.2 100.7 50.6 29.2 29.9 27.6 83.6 21.9 62.2 67.3 129.0 29.0 85.6 53.7 48.7 89.9 82.5 32.7 26.8 41.5 79.5 31.8 35.9 40.7 22.5 36.7 19.0 63.4 28.8 23.1 113.1 41.1 31.3 130.0 143.7 335.9 217.4 720.2 548.1 340.4 425.5 501.5 286.6 515.6 123.6 157.2 0.4 293.3 718.4 380.4 157.6 118.0 135.2 450.2 63.9 231.9 28.2 104.7 58.4 519.7 21.7 42.0 780.1 154.8 197.1 215.4 333.7 647.7 60.6 17.4 25.8 342.1 116.0 61.4 50.2 137.2 2.7 143.9 45.1 393.5 39.2 270.1 355.8 82.1 42.6 117.1 26.2 333.1 227.2 171.0 77.5 350.8 417.0 215.8 338.5 364.6 1.0 0.9 1.7 514.2 28.3 224.9 0.3 13.6 0.5 14.9 16.2 11.8 6.2 6.9 12.3 15.2 4.8 5.1 9.5 0.6 10.9 10.3 8.2 2.7 9.3 26.7 39.6 24.0 28.2 26.4 37.2 29.9 27.6 29.0 31.8 36.7 31.3 131.3 54.5 34.8 9.8 11.8 41.6 80.8 78.2 34.1 40.4 47.9 37.5 9.0 42.9 55.1 47.8 12.5 172.6 10.5 14.3 7.9 143.4 210.4 60.7 154.9 112.1 53.2 16.4 8.0 45.7 288.2 152.1 23.0 110.2 12.7 100.3 85.3 61.7 44.2 15.2 5.9 80.9 38.7 17.8 33.9 173.8 80.5 19.9 32.0 8.4 50.3 327.4 19.6 16.6 1.3 39.7 30.8 73.0 38.6 184.9 6.7 14.1 30.4 17.0 26.3 80.8 91.7 17.0 7.2 33.2 28.3 217.0 13.6 55.8 75.3 99.8 RCN2 "E6BP, ERC-55, ERC55, TCBP49" ENSG00000117906 "Reticulocalbin 2" Q14257 15 76931738-76954393 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 321.5" "Cell type enhanced" "Detected in all" "Spermatocytes: 528.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030694, HPA030695" Enhanced Supported Enhanced "Endoplasmic reticulum" "Intracellular and membrane" NA NA 92000 "Cluster 26: Non-specific - Mitochondria" "Cluster 68: Epididymis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Endoplasmic reticulum" "HPA030694: AB_2673573, HPA030695: AB_2673574" "unprognostic (1.69e-2)" "unprognostic (1.79e-1)" "unprognostic (1.92e-2)" "unprognostic (3.45e-2)" "unprognostic (2.42e-1)" "unprognostic (8.71e-2)" "prognostic unfavorable (7.36e-5)" "unprognostic (1.74e-1)" "unprognostic (2.20e-2)" "unprognostic (4.61e-3)" "unprognostic (1.39e-1)" "unprognostic (1.98e-1)" "unprognostic (1.70e-2)" "unprognostic (2.11e-2)" "unprognostic (2.99e-1)" "unprognostic (1.15e-1)" "unprognostic (3.67e-2)" 31.3 30.8 42.5 24.9 43.9 24.6 35.8 35.8 57.8 34.1 41.4 33.1 22.2 44.0 321.5 28.5 54.3 32.6 38.8 44.0 55.0 49.3 19.8 28.8 30.0 38.0 45.1 34.2 21.5 80.6 30.8 49.2 46.9 41.2 36.5 43.9 22.7 41.1 56.9 22.6 23.3 39.6 40.0 25.4 26.9 93.4 51.4 40.3 48.0 60.4 32.4 39.0 25.2 40.8 93.9 65.3 284.1 134.9 120.1 135.6 177.3 109.1 147.5 138.7 115.1 81.2 78.2 58.3 154.3 119.3 149.5 139.9 217.4 94.0 176.0 45.3 170.8 28.9 91.4 135.0 143.0 105.4 42.9 123.6 126.8 68.2 87.5 146.1 148.9 98.3 74.2 56.3 146.6 60.3 104.9 71.9 216.6 98.0 72.1 109.4 187.0 37.3 91.6 123.8 161.8 161.1 178.8 98.6 220.5 251.1 96.0 115.0 80.5 162.8 131.2 104.8 228.0 80.4 266.6 69.6 92.8 87.6 151.1 7.5 7.6 16.2 21.7 7.4 24.9 23.4 23.0 28.1 16.1 22.9 25.5 25.1 3.9 23.5 12.3 19.1 18.1 20.0 42.5 43.9 35.8 57.8 44.0 55.0 38.0 45.1 46.9 40.0 51.4 40.8 87.3 25.6 36.8 56.8 111.2 82.1 125.0 85.5 96.2 87.1 75.9 74.8 94.9 62.9 52.5 99.3 37.5 183.1 76.3 23.3 49.0 116.0 44.8 87.0 101.6 64.8 73.5 91.5 48.4 45.1 296.8 106.0 54.6 85.6 28.6 120.9 60.0 32.8 57.3 127.9 72.0 55.0 101.7 30.5 38.3 81.7 61.8 30.0 92.5 19.7 34.1 99.7 89.6 149.8 63.3 56.9 43.2 93.6 85.6 127.5 25.8 56.2 48.7 58.9 59.2 78.9 126.3 528.6 140.8 109.3 70.8 163.6 76.7 131.8 84.4 117.0 REEP2 "C5orf19, SGC32445, SPG72, Yip2d" ENSG00000132563 "Receptor accessory protein 2" Q9BRK0 5 138439057-138446969 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 155.7;choroid plexus: 77.8;retina: 61.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 47.3;Cone photoreceptor cells: 70.9;Excitatory neurons: 51.2;Horizontal cells: 48.8;Inhibitory neurons: 46.1;Muller glia cells: 29.8;Rod photoreceptor cells: 73.6" "Cancer enriched" "Detected in many" 9 "glioma: 31.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 97.3;SCLC-21H: 40.5;SH-SY5Y: 46.1;U-87 MG: 36.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031813, HPA076571" Enhanced Supported Approved "Endoplasmic reticulum" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 46: Photoreceptor cells - Phototransduction" "Endoplasmic reticulum" "HPA031813: AB_2674054, HPA076571: " "prognostic favorable (7.83e-5)" "unprognostic (1.11e-2)" "unprognostic (3.97e-6)" "unprognostic (3.70e-3)" "prognostic unfavorable (6.65e-4)" "unprognostic (5.43e-2)" "unprognostic (1.62e-2)" "unprognostic (1.04e-1)" "prognostic favorable (9.31e-4)" "unprognostic (5.93e-2)" "unprognostic (3.70e-3)" "unprognostic (9.78e-2)" "unprognostic (6.54e-3)" "unprognostic (7.54e-2)" "unprognostic (1.47e-3)" "unprognostic (6.19e-3)" "unprognostic (1.13e-3)" 4.6 9.5 106.7 2.5 102.5 0.3 3.0 93.5 155.7 3.6 77.8 18.8 1.8 7.0 1.4 4.4 3.6 2.6 24.8 110.3 110.7 1.9 0.2 0.8 0.4 134.6 109.1 4.0 2.0 1.8 54.5 0.6 136.4 8.6 2.2 61.2 1.8 8.0 16.6 2.4 4.3 12.6 77.5 0.4 7.6 6.2 130.6 1.9 1.2 5.7 0.5 8.7 4.6 104.7 0.6 7.4 27.6 97.3 3.9 10.5 0.0 8.4 3.8 11.4 12.9 5.3 1.0 0.1 1.5 10.5 0.2 0.6 26.1 5.4 8.6 3.1 23.7 0.0 1.8 12.6 9.8 0.1 0.1 3.2 0.3 6.4 0.5 19.9 2.3 27.6 0.1 6.9 3.6 4.4 2.7 1.8 17.2 0.0 0.3 9.7 2.6 0.0 2.1 0.0 40.5 46.1 2.9 0.1 7.5 7.0 2.6 0.9 0.2 6.6 6.6 6.4 15.9 18.1 12.3 0.8 36.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 106.7 102.5 93.5 155.7 110.3 110.7 134.6 109.1 136.4 77.5 130.6 104.7 17.0 0.0 0.0 18.9 0.1 0.6 1.0 1.6 2.2 47.3 0.7 3.3 9.8 0.0 0.2 1.8 70.9 0.0 0.3 0.0 0.0 0.0 1.1 0.4 0.3 5.6 4.8 0.4 51.2 0.0 0.0 3.7 0.0 0.1 0.0 1.5 0.7 0.0 0.1 48.8 46.1 0.0 0.0 0.0 0.7 5.0 0.0 0.3 0.0 2.8 0.1 29.8 0.0 19.1 5.7 0.1 0.0 2.6 1.3 0.4 3.6 0.3 0.6 73.6 0.0 7.6 2.9 0.3 9.1 0.0 0.4 0.0 0.8 0.1 0.1 0.2 REEP4 "C8orf20, FLJ22246, FLJ22277, PP432, Yip2c" ENSG00000168476 "Receptor accessory protein 4" Q9H6H4 8 22138020-22141951 "Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 89.3;skin 1: 91.0" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 94.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042683 Approved Supported "Endoplasmic reticulum" No Yes "Cluster 45: Eosinophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 2: Karpas-707 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Endoplasmic reticulum" "HPA042683: AB_2571730" "unprognostic (2.38e-1)" "unprognostic (9.96e-3)" "unprognostic (3.35e-2)" "unprognostic (2.38e-2)" "unprognostic (3.41e-2)" "unprognostic (7.75e-2)" "prognostic unfavorable (4.14e-5)" "unprognostic (1.83e-2)" "unprognostic (1.68e-1)" "unprognostic (1.91e-1)" "unprognostic (7.15e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (2.88e-5)" "unprognostic (5.72e-2)" "unprognostic (1.06e-1)" "unprognostic (2.25e-1)" "unprognostic (6.65e-2)" 13.0 8.4 7.0 12.5 8.7 28.4 11.6 8.7 9.7 27.9 7.6 23.8 11.0 9.4 2.1 89.3 11.1 5.6 8.0 6.8 8.2 9.2 12.3 18.0 11.2 10.8 8.5 7.4 12.9 5.0 10.9 14.6 10.5 13.6 10.8 2.1 21.8 6.5 4.1 91.0 16.9 5.9 9.0 33.2 18.0 42.7 9.5 9.9 14.8 2.6 10.2 19.6 49.0 11.5 42.2 79.7 24.9 39.7 10.5 10.6 47.9 36.7 19.2 44.6 40.2 46.7 38.8 53.0 46.8 18.4 38.5 100.3 29.6 59.3 21.9 28.2 37.4 57.4 41.2 46.9 11.8 25.8 77.9 9.8 110.3 33.3 27.5 13.9 27.1 58.1 44.5 158.7 22.6 60.6 63.7 88.9 37.4 58.0 53.3 37.0 22.5 101.8 19.9 40.0 21.7 40.1 30.0 31.7 52.7 16.5 64.3 35.9 30.5 29.2 50.1 66.6 50.3 40.0 33.5 34.6 32.6 54.7 59.1 49.8 54.8 64.1 24.3 53.6 19.6 10.5 21.1 21.1 42.7 4.9 9.7 13.1 15.5 26.3 37.0 16.9 15.4 27.6 7.0 8.7 8.7 9.7 6.8 8.2 10.8 8.5 10.5 9.0 9.5 11.5 6.8 3.2 9.2 4.9 7.9 28.0 15.1 45.5 15.4 6.5 5.8 5.7 1.8 7.2 21.9 12.9 2.1 54.0 13.8 27.3 0.0 21.9 16.0 3.8 4.9 9.2 17.4 48.2 0.7 15.0 50.4 8.1 21.9 5.9 10.2 14.0 15.4 6.6 55.4 0.0 0.6 33.0 22.4 38.8 21.5 9.4 9.0 26.1 3.6 10.3 16.5 1.8 10.3 1.0 2.6 25.6 34.7 8.2 19.3 19.0 19.2 1.9 8.1 1.5 13.1 2.3 9.7 61.0 17.9 41.1 39.2 94.1 13.5 8.9 31.1 24.5 REEP5 "C5orf18, D5S346, DP1, POB16, TB2, Yip2e" ENSG00000129625 "Receptor accessory protein 5" Q00765 5 112876385-112922289 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003895, HPA069960" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 6: T47d - Mammary gland" "Cluster 10: Non-specific - Unknown function" "Endoplasmic reticulum" "HPA003895: AB_1845723, HPA069960: AB_2686221" "unprognostic (3.26e-3)" "unprognostic (2.60e-1)" "unprognostic (2.71e-1)" "prognostic favorable (5.23e-6)" "unprognostic (8.29e-2)" "unprognostic (1.44e-2)" "unprognostic (1.13e-1)" "unprognostic (8.41e-2)" "unprognostic (2.85e-1)" "unprognostic (3.75e-2)" "unprognostic (7.75e-2)" "unprognostic (5.90e-2)" "prognostic favorable (2.05e-5)" "unprognostic (2.88e-2)" "unprognostic (4.14e-2)" "unprognostic (1.83e-1)" "unprognostic (3.24e-2)" 76.9 105.4 97.1 50.5 100.2 27.3 130.6 92.7 120.7 87.1 76.8 66.6 56.8 58.4 120.0 52.1 64.7 60.8 133.2 107.3 110.5 148.0 124.3 80.4 48.2 112.2 104.8 72.2 123.0 140.7 41.5 66.6 115.2 98.9 58.1 81.5 147.7 84.2 114.3 59.1 58.1 55.0 96.4 54.3 70.2 28.3 120.0 32.1 239.4 99.6 56.7 73.2 49.1 98.3 101.7 90.9 29.7 72.5 136.0 115.9 104.7 102.2 92.6 96.4 103.4 74.9 138.1 42.5 179.6 105.1 112.5 107.5 66.8 138.9 88.5 190.6 116.4 42.8 56.3 63.5 126.8 36.9 77.4 81.3 136.0 82.2 78.0 94.5 113.7 38.7 26.0 84.5 121.3 100.0 15.7 60.7 43.4 73.5 75.3 22.4 84.3 116.6 229.1 108.4 56.9 43.1 148.5 244.6 99.8 75.5 287.3 58.9 142.4 83.4 32.0 126.5 126.4 97.6 126.2 33.8 142.6 65.4 47.8 224.4 222.9 234.3 140.1 249.5 149.4 175.7 112.7 133.9 189.0 149.2 52.5 94.6 253.0 112.7 316.2 133.6 177.9 236.4 97.1 100.2 92.7 120.7 107.3 110.5 112.2 104.8 115.2 96.4 120.0 98.3 141.2 166.7 102.3 30.0 131.1 93.0 177.7 291.6 89.4 83.5 225.3 188.1 217.3 145.8 213.7 195.0 89.6 296.0 138.4 77.0 82.2 275.1 231.5 111.8 97.0 130.5 118.0 34.9 78.6 414.1 352.8 182.3 65.7 141.6 108.9 76.0 118.2 197.0 267.1 87.5 95.0 127.5 256.3 135.0 159.9 42.0 116.2 168.8 206.3 36.5 188.6 97.2 101.0 44.7 71.5 316.5 141.1 133.9 271.6 225.3 134.1 146.1 170.6 80.0 111.7 92.6 253.0 162.8 63.9 118.1 101.6 489.8 123.7 100.3 104.5 214.8 REEP6 "C19orf32, DP1L1, FLJ25383, Yip2f" ENSG00000115255 "Receptor accessory protein 6" Q96HR9 19 1491166-1497927 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 217.5;liver: 398.0;testis: 283.9" "Cell type enhanced" "Detected in many" "Early spermatids: 559.1;Late spermatids: 3135.0;Proximal enterocytes: 898.7" "Cancer enhanced" "Detected in all" "liver cancer: 114.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 57.9;Hep G2: 56.2;K-562: 155.7;T-47d: 121.4" "HPA003895, HPA048015" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 45: Intestine - Brush border" "Cluster 1: K-562 - Erythropoiesis" "Cluster 25: Spermatids - Spermatogenesis" "Endoplasmic reticulum" "HPA003895: AB_1845723, HPA048015: AB_2680233" "unprognostic (1.21e-1)" "unprognostic (1.56e-1)" "unprognostic (7.76e-2)" "unprognostic (1.63e-3)" "unprognostic (3.24e-1)" "unprognostic (2.43e-2)" "unprognostic (1.92e-1)" "unprognostic (6.85e-2)" "unprognostic (7.38e-2)" "unprognostic (4.56e-1)" "unprognostic (1.49e-1)" "unprognostic (1.93e-1)" "unprognostic (1.40e-2)" "unprognostic (2.17e-1)" "unprognostic (8.08e-2)" "unprognostic (2.83e-1)" "unprognostic (5.38e-2)" 8.4 86.5 11.1 1.3 12.4 1.2 17.5 10.1 18.0 5.6 7.7 3.0 217.5 3.5 14.6 14.3 4.6 7.0 3.9 12.7 8.8 22.1 398.0 1.6 1.3 9.7 10.1 7.7 28.5 2.0 9.8 1.6 9.9 20.1 1.7 94.0 17.9 6.8 2.0 9.3 199.6 0.9 8.4 1.7 4.2 283.9 12.1 0.7 6.0 0.7 1.0 9.2 7.0 10.9 7.3 9.2 2.6 34.3 5.6 2.0 39.5 1.8 0.7 1.9 1.9 57.9 22.5 3.9 12.2 1.1 2.3 7.3 9.8 0.6 1.0 1.9 4.1 21.3 1.3 56.2 4.2 1.6 6.6 4.7 4.1 0.4 1.4 3.2 1.1 4.9 155.7 5.0 0.3 29.6 1.8 4.7 12.8 21.1 19.5 4.9 1.1 10.0 10.9 2.7 0.7 17.2 9.8 14.2 6.3 1.9 121.4 5.7 3.4 2.8 5.4 8.7 1.2 16.4 5.3 0.8 11.2 9.4 8.2 0.0 1.1 0.0 5.5 1.2 2.8 0.1 1.4 1.2 1.9 0.6 2.0 2.2 0.0 4.9 4.3 3.3 1.6 1.6 11.1 12.4 10.1 18.0 12.7 8.8 9.7 10.1 9.9 8.4 12.1 10.9 1.5 3.2 3.2 2.6 2.7 6.8 7.9 6.8 10.8 30.4 47.4 20.3 1.8 91.5 10.5 5.5 33.3 69.4 2.5 7.8 7.9 34.5 559.1 4.5 7.1 4.2 6.0 10.1 1.5 69.2 12.8 4.7 2.6 3.0 10.2 132.9 5.0 267.4 9.6 23.5 1.2 51.9 4.1 6.3 4.3 3135.0 34.2 4.1 30.2 0.0 1.7 44.2 2.1 0.0 1.5 25.0 53.6 16.6 1.9 13.1 898.7 52.0 8.3 292.8 19.7 0.8 3.3 29.9 36.5 17.5 6.7 36.0 4.3 50.1 70.7 14.7 RETREG1 "FAM134B, FLJ20152, JK1" ENSG00000154153 "Reticulophagy regulator 1" Q9H6L5 5 16473038-16617038 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Autophagy "Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 91.4;skeletal muscle: 141.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 73.7;Cytotrophoblasts: 53.7;Exocrine glandular cells: 59.3;Glandular and luminal cells: 197.7;Pancreatic endocrine cells: 51.5;Proximal tubular cells: 152.8" "Cancer enhanced" "Detected in all" "renal cancer: 28.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.3" "Group enriched" "Detected in many" 6 "granulocytes: 2.3;T-cells: 1.7" "Cell line enhanced" "Detected in many" "ASC diff: 26.0;GAMG: 20.3;HSkMC: 28.8;MOLT-4: 20.4;RPTEC TERT1: 26.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012077 Supported "Endoplasmic reticulum" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 44: Endometrium - Transcription" "Endoplasmic reticulum" "HPA012077: AB_2668621" "unprognostic (1.63e-2)" "unprognostic (1.98e-1)" "unprognostic (1.80e-2)" "unprognostic (1.84e-2)" "unprognostic (4.96e-2)" "unprognostic (9.17e-3)" "unprognostic (2.66e-2)" "unprognostic (1.90e-1)" "unprognostic (4.35e-2)" "unprognostic (4.41e-2)" "unprognostic (1.37e-2)" "unprognostic (1.48e-1)" "prognostic favorable (5.25e-10)" "unprognostic (3.75e-1)" "unprognostic (9.96e-2)" "unprognostic (5.62e-2)" "unprognostic (2.58e-1)" 15.6 3.5 20.6 6.6 26.4 2.0 13.6 23.9 33.2 13.2 21.6 24.6 12.6 4.0 5.2 3.6 7.5 13.4 91.4 19.4 22.1 61.0 44.2 9.3 6.4 27.2 25.2 2.1 37.7 30.1 9.9 13.2 27.8 11.1 32.4 7.5 5.2 5.0 141.8 10.0 25.6 2.6 23.6 2.3 10.9 12.3 25.0 20.6 6.7 81.9 4.3 2.3 5.2 37.6 1.3 0.5 0.1 3.5 26.0 3.2 15.1 0.1 3.5 3.1 4.1 2.3 0.1 0.3 2.4 0.0 20.3 3.9 7.8 0.8 1.0 4.1 3.4 0.0 10.6 0.0 0.1 5.3 0.0 28.8 11.7 0.6 3.1 7.5 0.0 15.4 0.0 0.1 1.2 1.0 20.4 0.1 0.8 3.4 0.6 3.2 0.0 1.2 26.2 0.9 17.4 2.0 1.0 1.1 13.1 1.9 5.9 2.4 0.0 2.4 0.2 6.4 3.1 0.7 0.0 0.0 14.9 18.0 6.5 2.3 0.1 0.0 0.2 0.0 0.6 0.0 0.6 0.3 0.0 0.3 1.7 1.0 0.9 0.0 0.0 0.0 0.8 0.2 20.6 26.4 23.9 33.2 19.4 22.1 27.2 25.2 27.8 23.6 25.0 37.6 4.2 73.7 8.6 0.0 3.4 0.0 0.0 0.0 0.0 0.0 33.3 19.0 0.0 0.0 9.9 44.1 0.0 53.7 2.2 0.0 17.6 31.1 0.0 33.5 45.2 1.2 0.0 0.0 0.0 59.3 2.0 7.8 0.0 197.7 1.3 3.3 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 1.0 0.0 0.0 0.0 0.0 51.5 0.0 0.0 0.8 0.0 0.0 152.8 19.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 10.9 8.1 0.3 0.0 0.0 RHAG "CD241, RH50A, SLC42A1" ENSG00000112077 "Rh associated glycoprotein" Q02094 6 49605175-49636839 "CD markers, Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ammonia transport, Transport" "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 54 "bone marrow: 119.6" "Cell type enriched" "Detected in some" 170 "Erythroid cells: 494.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 202 "HEL: 506.0;K-562: 491.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA046051, HPA055331" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 67: Neutrophils - Humoral immune response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" "Endoplasmic reticulum" "HPA046051: , HPA055331: AB_2682785" "unprognostic (8.16e-2)" "unprognostic (6.86e-2)" "unprognostic (1.25e-3)" "unprognostic (1.65e-1)" 0.2 0.0 0.0 0.0 0.0 119.6 0.0 0.0 0.0 0.7 0.0 0.5 0.1 0.1 0.0 0.1 0.2 0.0 2.1 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.2 0.0 0.2 0.2 0.0 0.2 0.6 0.0 0.1 0.4 0.0 0.0 1.7 0.2 0.1 0.0 0.1 0.1 0.1 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 506.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 491.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.4 0.4 0.1 0.3 0.0 494.2 0.2 0.2 0.6 0.3 0.0 0.6 2.5 0.0 1.1 0.1 0.5 0.0 0.1 0.0 0.0 0.6 0.3 2.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.4 0.1 0.0 0.0 RHBDD1 DKFZp547E052 ENSG00000144468 "Rhomboid domain containing 1" Q8TEB9 2 226835581-226999215 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Differentiation, Spermatogenesis" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 66.9;Microglial cells: 57.1;Oligodendrocyte precursor cells: 55.8;Oligodendrocytes: 109.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-698: 73.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013972, HPA057125" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 57: B-cells - Immune response" "Endoplasmic reticulum" "HPA013972: AB_2178629, HPA057125: AB_2683343" "unprognostic (1.42e-1)" "unprognostic (5.37e-2)" "unprognostic (3.26e-1)" "unprognostic (5.23e-2)" "unprognostic (2.57e-1)" "unprognostic (2.91e-1)" "unprognostic (1.17e-2)" "unprognostic (2.07e-2)" "unprognostic (1.18e-1)" "unprognostic (9.40e-2)" "unprognostic (4.74e-3)" "unprognostic (4.97e-2)" "unprognostic (1.16e-1)" "unprognostic (1.79e-1)" "unprognostic (1.09e-1)" "unprognostic (9.77e-2)" "unprognostic (3.04e-2)" 10.3 8.9 11.2 13.6 20.9 11.9 11.5 12.2 13.6 11.6 1.8 11.5 10.3 13.6 12.5 11.5 12.9 10.9 10.3 8.8 15.2 12.0 15.1 9.9 16.1 15.6 15.0 13.6 13.9 16.5 4.4 9.9 17.1 13.1 11.2 7.4 9.6 13.3 8.9 8.8 11.8 14.3 15.7 14.2 11.4 17.4 16.8 37.5 15.6 8.6 16.9 11.5 7.0 22.8 10.7 9.3 9.9 15.1 28.6 28.8 0.0 24.1 20.9 12.6 14.6 8.3 18.7 10.1 19.8 25.2 18.0 11.9 0.1 26.8 23.9 25.1 9.9 15.3 5.9 6.7 31.5 15.2 8.0 25.6 38.2 23.8 51.4 14.3 9.8 26.7 41.7 25.6 13.4 18.9 27.8 8.5 0.0 12.2 10.3 12.0 0.1 14.9 10.3 13.3 9.7 7.3 13.6 5.1 18.8 17.6 14.1 18.9 13.1 5.6 12.2 22.0 7.5 28.8 14.9 73.9 17.8 19.6 16.2 10.4 13.7 12.8 7.3 20.0 11.8 22.1 11.0 8.9 17.2 24.5 12.6 10.6 3.3 11.8 13.8 21.1 16.2 10.8 11.2 20.9 12.2 13.6 8.8 15.2 15.6 15.0 17.1 15.7 16.8 22.8 6.6 12.8 6.4 66.9 28.4 5.2 8.5 7.2 8.0 8.0 7.6 4.2 16.6 4.3 8.1 11.0 16.7 7.6 9.3 6.6 3.9 7.0 16.7 8.3 8.6 6.8 1.8 15.2 28.4 9.3 4.1 9.3 8.2 7.8 8.2 22.7 3.3 14.0 5.2 11.8 41.5 6.1 6.1 8.2 4.4 24.4 5.6 7.6 12.4 57.1 6.2 6.3 9.2 55.8 109.0 8.3 1.9 6.8 48.8 13.2 6.8 3.4 7.1 6.3 0.0 5.6 6.6 15.2 9.5 7.3 5.5 5.6 8.6 25.7 5.7 8.9 RNF5 "G16, NG2, RING5, RMA1" ENSG00000204308 "Ring finger protein 5" Q99942 6 32178405-32180793 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 371.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034107, HPA065032" Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Endoplasmic reticulum" "CAB034107: AB_2238618, HPA065032: AB_2685408" "unprognostic (1.94e-1)" "unprognostic (1.31e-1)" "unprognostic (1.49e-1)" "unprognostic (4.45e-3)" "unprognostic (1.35e-2)" "unprognostic (1.23e-1)" "unprognostic (1.36e-1)" "unprognostic (1.37e-2)" "unprognostic (4.07e-1)" "prognostic favorable (2.44e-4)" "unprognostic (1.95e-1)" "unprognostic (8.93e-3)" "unprognostic (2.91e-3)" "unprognostic (8.84e-2)" "unprognostic (9.17e-2)" "unprognostic (2.72e-1)" "unprognostic (2.99e-2)" 38.2 75.9 60.4 29.2 63.4 40.4 44.5 64.6 66.0 44.9 59.4 59.5 61.6 44.8 45.8 37.5 54.1 46.1 81.7 59.2 60.6 115.6 126.2 38.7 43.1 65.0 60.6 60.4 41.6 55.5 17.2 30.1 62.6 44.0 62.4 42.9 43.9 31.7 89.6 44.6 76.5 30.5 62.8 38.8 55.3 29.5 61.8 60.7 48.6 76.5 43.4 45.1 38.8 67.0 51.2 66.1 43.7 167.5 46.9 31.3 34.0 20.6 26.5 44.4 48.7 89.1 42.1 65.2 70.8 47.9 62.5 41.7 80.3 45.1 45.2 41.8 107.5 53.9 69.5 184.4 55.0 0.2 101.2 32.3 60.3 73.3 53.6 77.2 89.1 115.0 136.6 67.8 63.8 71.9 66.5 151.5 0.3 71.8 28.7 44.4 48.2 88.2 124.0 32.6 44.8 92.1 39.9 42.4 46.7 39.9 87.0 183.0 40.3 48.1 44.7 0.5 79.1 38.6 63.5 79.3 33.2 116.4 29.6 64.8 45.7 75.8 64.8 65.9 55.6 64.6 52.5 57.6 64.7 56.2 57.5 58.3 22.1 79.6 46.7 264.6 58.2 75.0 60.4 63.4 64.6 66.0 59.2 60.6 65.0 60.6 62.6 62.8 61.8 67.0 38.3 19.2 41.1 2.9 52.7 95.7 70.0 146.6 52.3 23.6 61.8 56.5 62.9 87.2 79.5 92.0 0.0 78.1 70.3 151.9 283.7 110.8 21.6 47.2 31.7 50.9 73.2 126.3 3.4 91.3 101.7 44.6 28.5 31.7 56.3 41.5 47.8 131.5 68.9 33.7 3.5 83.0 132.2 51.1 171.7 22.6 59.4 43.3 85.4 1.0 69.5 91.3 65.9 1.5 10.0 78.5 173.0 72.6 45.5 58.4 270.6 371.6 73.4 27.6 65.7 50.6 63.0 55.7 37.7 44.4 84.4 84.1 53.8 42.8 100.3 56.5 RPL41 L41 ENSG00000229117 "Ribosomal protein L41" P62945 12 56116590-56117967 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast myoepithelial cells: 35670.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA053169 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum" "HPA053169: AB_2682067" "unprognostic (7.99e-2)" "unprognostic (1.07e-1)" "unprognostic (2.11e-1)" "unprognostic (3.53e-2)" "unprognostic (8.94e-2)" "unprognostic (1.43e-1)" "unprognostic (4.61e-3)" "unprognostic (1.50e-1)" "unprognostic (1.30e-1)" "unprognostic (1.40e-1)" "unprognostic (2.14e-2)" "unprognostic (1.79e-1)" "unprognostic (8.79e-2)" "unprognostic (1.80e-1)" "unprognostic (1.46e-1)" "unprognostic (1.18e-1)" "unprognostic (1.19e-1)" 3936.1 4294.0 3557.6 3101.7 3613.5 6945.6 7552.2 3463.0 4861.4 4729.6 3626.0 4637.2 3164.3 3213.6 5188.3 5197.9 4452.5 2395.7 3076.1 3477.3 3785.5 3342.3 4356.3 3110.7 5506.9 3599.0 3568.2 8695.6 8504.0 4160.3 3131.9 2392.0 3600.6 4113.2 4408.4 1725.9 5119.7 2985.6 6133.0 6292.8 3521.6 2870.0 3637.4 3885.7 4297.4 964.0 3697.2 5319.2 3521.9 4727.8 6456.2 4672.0 4325.6 3592.3 6313.5 7806.3 7002.4 4830.9 7462.6 11563.8 4509.5 5592.4 7268.0 6990.8 5609.0 7636.8 7281.1 11851.0 7075.7 7144.1 2202.9 5093.1 8802.0 9018.4 6003.8 4866.6 8636.4 5198.6 5743.2 7893.5 8420.9 9422.8 4324.7 12971.4 11986.3 6362.7 13815.8 13392.7 8210.7 6311.2 5234.4 11000.9 6880.6 11434.7 8612.8 13968.6 8415.8 7977.4 7366.9 6352.2 6645.3 9568.4 9027.5 8830.5 4162.2 7204.8 5240.2 7801.5 11830.4 4744.8 9323.1 11208.4 5182.2 2985.4 5510.3 3766.0 5664.5 4989.5 9471.9 9750.5 4626.0 7490.8 3249.4 5072.5 5556.2 2971.9 6805.5 4758.3 9483.2 13388.0 10983.9 8845.1 6687.5 11498.7 11453.0 10037.6 2088.9 6839.0 4546.0 8108.0 9032.3 22344.5 3557.6 3613.5 3463.0 4861.4 3477.3 3785.5 3599.0 3568.2 3600.6 3637.4 3697.2 3592.3 5593.1 2484.0 4469.3 30.3 8258.1 20641.6 3999.9 15748.5 2099.5 489.3 25242.7 35670.2 584.2 6852.9 7643.1 3948.6 218.9 5477.3 8310.1 4631.3 10318.6 6428.1 822.2 3402.2 5615.0 4720.6 5139.1 3676.0 34.1 17900.6 8796.9 4448.1 803.8 4299.0 3546.3 5173.9 6544.8 10920.0 5896.5 213.7 31.0 11437.4 4752.5 9497.7 16486.3 3378.1 6739.8 4472.1 11120.4 34.7 11045.4 2983.4 7243.1 20.1 42.9 11407.4 10209.4 2920.3 2410.0 4695.0 12534.2 12547.9 4754.9 804.3 2143.1 4895.2 5070.6 550.0 666.0 3054.1 25829.7 5993.0 7150.4 4176.6 12114.5 4014.3 RPN2 "RIBIIR, RPN-II, RPNII, SWP1" ENSG00000118705 "Ribophorin II" P04844 20 37178410-37241619 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 599.6;Syncytiotrophoblasts: 621.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008297, CAB019277, HPA025922" Enhanced Supported "Endoplasmic reticulum" NA NA 1300000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "CAB019277: , HPA008297: AB_1856457, HPA025922: AB_1856458" "unprognostic (9.59e-3)" "unprognostic (5.22e-2)" "unprognostic (1.66e-2)" "unprognostic (1.06e-1)" "unprognostic (1.99e-1)" "unprognostic (1.20e-2)" "prognostic unfavorable (1.38e-4)" "unprognostic (1.82e-2)" "unprognostic (1.09e-1)" "unprognostic (2.58e-1)" "unprognostic (1.06e-1)" "unprognostic (2.14e-1)" "prognostic unfavorable (1.44e-10)" "unprognostic (2.83e-1)" "unprognostic (6.99e-2)" "unprognostic (2.03e-1)" "prognostic unfavorable (2.44e-4)" 112.6 132.5 48.2 131.9 50.4 180.8 146.1 49.9 55.9 161.8 98.0 156.9 125.5 108.7 344.1 106.8 122.9 119.8 107.3 49.5 56.5 145.1 212.1 129.7 109.2 54.0 50.6 94.8 159.6 180.9 79.1 257.9 53.9 164.4 175.2 117.0 158.2 157.5 110.4 91.5 110.9 156.6 53.8 118.1 145.1 144.2 55.4 108.5 232.5 75.1 143.3 165.4 87.9 61.9 328.2 290.6 302.7 401.2 413.1 308.2 586.7 426.7 516.8 544.8 459.2 939.2 564.8 255.3 501.6 572.3 506.4 468.4 318.8 516.4 492.0 121.2 196.5 295.3 308.4 634.1 398.9 468.4 467.0 294.6 505.1 432.3 447.5 519.8 530.4 239.2 458.7 805.1 389.1 300.9 270.6 451.0 240.4 839.3 415.7 242.3 549.1 852.7 371.6 304.3 246.4 261.0 517.9 1231.1 489.4 353.6 606.1 765.6 338.0 600.8 358.2 317.1 371.9 474.7 608.4 259.9 583.4 314.9 493.2 424.2 427.5 285.5 365.5 410.5 417.0 291.0 336.1 363.8 481.2 232.4 298.8 308.7 78.3 398.8 357.6 591.0 338.2 676.5 48.2 50.4 49.9 55.9 49.5 56.5 54.0 50.6 53.9 53.8 55.4 61.9 85.7 118.6 158.0 22.2 107.8 61.8 134.1 264.6 62.0 72.6 90.0 74.2 81.4 133.0 197.7 80.9 45.9 461.6 109.6 113.9 23.5 278.0 37.3 73.2 103.5 98.6 63.0 91.7 18.8 241.1 599.6 127.4 84.1 151.2 105.2 109.3 100.6 206.3 233.2 63.9 18.6 168.5 162.8 150.4 75.3 24.4 105.0 117.0 90.7 20.6 122.2 136.8 65.9 24.1 20.5 160.1 109.5 110.9 392.3 121.3 64.6 82.3 98.5 100.8 85.5 65.3 122.0 335.2 288.9 67.7 57.8 621.0 81.5 213.7 138.7 117.6 RPS13 S13 ENSG00000110700 "Ribosomal protein S13" P62277 11 17074388-17077715 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005985 Uncertain Approved "Endoplasmic reticulum" NA NA 190000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum" "HPA005985: AB_10960703" "unprognostic (7.74e-3)" "unprognostic (2.73e-1)" "unprognostic (2.03e-1)" "unprognostic (3.21e-3)" "unprognostic (2.88e-1)" "unprognostic (4.85e-2)" "unprognostic (8.68e-3)" "unprognostic (3.81e-1)" "unprognostic (1.41e-1)" "unprognostic (3.74e-2)" "unprognostic (8.20e-3)" "unprognostic (1.31e-1)" "prognostic unfavorable (1.54e-4)" "unprognostic (5.71e-2)" "unprognostic (3.85e-2)" "unprognostic (2.62e-1)" "unprognostic (1.03e-1)" 1087.7 732.8 827.4 821.7 866.8 2404.4 2065.5 844.9 1205.2 1301.5 834.4 1135.5 854.6 1115.2 1152.5 1160.4 1285.2 950.2 1064.7 797.8 862.5 845.3 1101.5 696.5 2031.2 867.4 824.3 2669.7 1736.0 646.3 520.4 981.3 878.5 814.1 1136.1 660.8 1368.0 829.6 1934.5 1450.1 817.7 947.1 897.4 1102.7 962.6 356.6 856.5 1737.4 997.0 1525.9 1845.3 1318.5 1070.0 910.6 2115.6 1619.7 1524.1 1279.1 2680.1 4138.4 1660.6 1430.9 1991.9 2194.7 1774.8 2580.3 2640.4 3164.1 975.4 1710.4 1405.0 1546.0 2213.2 2387.6 2309.0 1326.2 4617.5 1347.9 1531.6 2761.0 3226.4 2821.8 1400.8 3174.0 3942.6 917.4 3647.4 2486.7 2632.2 2073.1 2128.5 1736.5 2173.6 2173.4 2377.2 3920.5 1727.0 2853.9 3099.3 2189.8 2064.2 2008.3 2147.5 2483.2 1249.0 2080.7 682.1 2723.3 3495.9 1527.1 1238.1 4255.9 1550.7 997.4 1660.5 2271.0 1835.2 1186.2 2726.3 2444.2 1143.1 2407.0 1352.5 582.6 2489.7 362.9 1356.0 1807.4 2715.0 3719.8 2904.9 2027.9 3004.4 3245.9 4371.9 3365.9 232.1 1880.4 1483.8 3192.8 2173.3 6018.5 827.4 866.8 844.9 1205.2 797.8 862.5 867.4 824.3 878.5 897.4 856.5 910.6 2429.5 926.3 1565.1 24.8 4390.9 4567.0 4447.1 4666.4 4408.4 271.6 5079.9 8516.0 778.1 1998.8 2361.4 665.8 104.3 3971.3 2743.0 912.1 2915.1 2434.7 1352.5 1075.0 2375.9 2226.1 1369.9 2311.8 19.4 4554.7 5434.6 2170.0 1711.1 1305.6 1506.6 2246.3 2328.4 2036.1 2923.8 90.9 24.7 2896.7 1501.4 4367.6 4707.0 1820.3 3551.8 2950.1 2180.6 30.9 4862.5 1677.2 2326.5 18.6 33.1 2988.2 2321.6 1774.6 2669.5 4100.7 1793.2 3790.7 1206.8 482.6 874.4 3314.3 2545.4 616.6 352.4 5638.8 5447.9 4488.7 3426.6 2642.9 3153.8 4835.4 RRBP1 "ES/130, hES" ENSG00000125844 "Ribosome binding protein 1" Q9P2E9 20 17613678-17682295 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 497.7" "Cell type enhanced" "Detected in all" "Distal enterocytes: 588.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 37.8;plasmacytoid DC: 44.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009026, HPA011924" Enhanced Enhanced "Endoplasmic reticulum" NA NA 320000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 25: Pancreas - Digestion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Endoplasmic reticulum" "HPA009026: AB_1079852, HPA011924: AB_1856476" "unprognostic (1.56e-3)" "unprognostic (2.26e-3)" "unprognostic (8.46e-2)" "prognostic favorable (1.41e-4)" "unprognostic (1.04e-1)" "unprognostic (1.05e-1)" "unprognostic (2.92e-2)" "unprognostic (2.21e-1)" "unprognostic (1.22e-1)" "unprognostic (2.33e-1)" "unprognostic (6.89e-2)" "unprognostic (3.03e-1)" "unprognostic (5.09e-2)" "unprognostic (6.63e-2)" "unprognostic (9.21e-3)" "unprognostic (1.54e-1)" "prognostic unfavorable (9.38e-4)" 64.2 72.3 27.0 62.8 41.9 28.1 54.6 41.1 32.2 69.1 52.3 98.3 76.1 59.5 55.0 67.8 45.1 71.5 59.1 27.5 35.3 77.4 219.0 80.2 28.2 49.3 42.2 48.3 497.7 72.4 63.4 107.9 45.5 66.5 65.9 17.7 228.2 63.4 21.9 43.6 82.7 46.0 37.7 57.7 123.1 48.4 40.9 14.4 130.4 14.7 27.0 57.6 55.2 49.2 173.5 121.0 35.7 80.4 160.3 172.2 186.2 264.3 221.3 110.0 148.2 271.2 159.3 66.5 87.3 252.2 113.4 170.4 38.7 215.4 89.1 30.9 29.7 76.2 34.9 283.6 229.4 29.0 93.0 228.9 63.8 178.7 104.3 161.7 109.7 23.4 32.6 62.9 167.6 78.8 11.4 65.5 41.6 383.3 115.8 20.1 94.2 231.3 93.0 58.4 18.2 13.7 151.1 353.2 108.4 75.0 62.0 43.5 198.7 232.7 85.9 122.1 88.5 114.6 93.6 21.6 88.1 30.7 121.1 11.7 8.4 37.8 4.3 5.5 3.2 1.0 1.4 2.6 4.6 1.4 1.4 1.6 7.8 10.7 8.4 44.4 1.5 3.1 27.0 41.9 41.1 32.2 27.5 35.3 49.3 42.2 45.5 37.7 40.9 49.2 146.8 96.1 197.1 15.0 72.5 59.1 92.3 90.3 55.2 21.9 127.0 76.3 46.4 144.4 158.2 95.6 31.3 262.0 180.6 588.9 45.0 199.7 47.2 117.5 228.4 155.8 97.0 31.6 3.0 414.6 235.8 219.7 294.6 322.8 118.9 78.1 118.9 279.9 117.4 25.2 4.9 507.9 50.8 62.0 85.7 44.3 127.1 91.6 71.2 17.8 75.1 144.3 79.3 23.1 27.6 357.7 452.3 83.1 570.6 145.6 221.6 57.2 121.8 35.5 32.9 165.1 169.8 77.5 139.9 73.2 55.8 532.9 56.9 114.6 329.3 218.5 RTBDN FLJ36353 ENSG00000132026 Retbindin Q9BSG5 19 12825478-12835428 "Predicted membrane proteins, Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "retina: 288.0" "Group enriched" "Detected in some" 5 "Cone photoreceptor cells: 350.3;Rod photoreceptor cells: 524.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SCLC-21H: 8.3;SH-SY5Y: 5.4;U-266/84: 23.1;U-87 MG: 4.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA052511 Approved "Endoplasmic reticulum" "Secreted in other tissues" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 16: U-266 - Nucleosome" "Cluster 46: Photoreceptor cells - Phototransduction" "Endoplasmic reticulum" "HPA052511: AB_2797243" "unprognostic (4.55e-4)" "unprognostic (3.94e-3)" "unprognostic (2.18e-1)" "unprognostic (1.54e-4)" "unprognostic (3.33e-2)" "unprognostic (2.18e-1)" "unprognostic (1.08e-2)" "unprognostic (2.45e-2)" "unprognostic (2.02e-2)" "unprognostic (3.55e-1)" "unprognostic (6.48e-2)" "unprognostic (7.04e-3)" "unprognostic (7.66e-9)" "unprognostic (3.55e-2)" "unprognostic (1.00e-1)" "unprognostic (7.05e-2)" "unprognostic (2.24e-2)" 0.0 3.5 5.1 0.1 5.9 0.2 0.0 1.9 10.0 0.0 0.9 1.1 0.4 0.0 0.6 0.0 0.0 0.0 0.0 6.7 2.7 0.0 0.0 0.1 0.0 2.7 1.9 0.0 1.2 0.3 34.3 0.0 5.8 0.0 0.3 288.0 0.0 0.0 0.0 0.1 0.5 0.1 0.9 0.0 1.1 3.3 2.9 8.7 0.0 0.0 0.0 0.0 0.1 3.2 0.9 0.1 0.1 0.6 0.0 0.0 0.7 0.0 0.0 0.4 0.0 0.3 0.0 0.9 0.9 0.0 0.6 0.3 0.3 0.0 0.0 0.0 0.1 0.0 0.4 0.9 0.0 0.1 2.4 0.0 0.0 0.4 0.2 0.0 0.0 0.1 1.3 2.7 0.0 0.1 0.1 0.0 0.9 0.7 1.1 0.7 0.1 1.1 0.1 0.0 8.3 5.4 0.1 0.0 0.4 0.4 2.8 0.7 0.0 0.8 1.0 0.7 0.1 1.2 23.1 4.3 4.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.1 5.9 1.9 10.0 6.7 2.7 2.7 1.9 5.8 0.9 2.9 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 50.5 0.0 0.0 1.4 0.0 0.1 0.0 350.3 0.0 0.0 0.5 0.0 0.0 0.5 0.1 0.0 1.8 0.0 0.0 2.8 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.6 2.5 0.6 4.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 84.4 0.0 1.0 0.7 0.1 0.1 0.0 0.5 0.0 0.7 0.1 0.0 524.0 0.0 0.1 0.0 16.2 5.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 RTN3 "ASYIP, HAP, NSPL2, NSPLII, RTN3-A1" ENSG00000133318 "Reticulon 3" O95197 11 63681446-63759891 "Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, ER-Golgi transport, Host-virus interaction, Stress response, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 514.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1074.7" "Group enriched" "Detected in all" 6 "granulocytes: 1074.7;monocytes: 400.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015649, HPA015650" Enhanced Supported "Endoplasmic reticulum" NA NA 130000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 65: Brain - Ion transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "HPA015649: AB_1856498, HPA015650: AB_1856499" "unprognostic (8.11e-3)" "unprognostic (8.51e-2)" "unprognostic (3.61e-2)" "unprognostic (7.88e-3)" "unprognostic (1.41e-1)" "unprognostic (1.74e-2)" "prognostic unfavorable (1.30e-6)" "unprognostic (5.49e-2)" "unprognostic (1.25e-1)" "unprognostic (1.07e-2)" "unprognostic (2.70e-2)" "unprognostic (1.07e-1)" "prognostic favorable (9.87e-4)" "unprognostic (1.60e-2)" "unprognostic (2.54e-1)" "unprognostic (2.73e-2)" "unprognostic (1.57e-2)" 207.5 81.8 361.4 54.1 412.2 108.5 93.3 338.4 514.5 87.6 190.7 88.1 54.0 62.5 81.2 55.7 88.5 56.3 57.4 428.4 378.9 92.8 87.5 77.8 36.0 404.5 309.1 48.1 91.1 109.9 81.0 62.2 417.2 53.3 79.9 194.4 138.8 76.1 70.2 103.7 65.2 80.1 329.2 51.7 57.0 46.6 334.0 53.7 175.5 43.7 48.5 55.7 54.2 384.0 157.5 113.8 134.0 128.4 242.3 170.9 53.4 139.3 147.5 120.5 128.4 99.6 338.1 184.2 231.7 210.0 115.7 157.2 194.0 68.7 157.5 149.5 103.5 236.5 151.3 70.4 201.1 212.8 182.4 113.5 199.2 146.7 162.3 200.7 165.2 158.9 136.2 290.1 107.4 129.2 113.4 235.2 156.7 127.3 127.3 148.4 93.8 342.9 239.7 87.5 282.7 164.0 226.2 245.3 271.5 95.4 271.1 172.7 155.2 71.3 95.6 251.1 108.4 183.4 169.9 145.6 274.7 173.8 77.2 441.0 400.1 487.7 41.4 187.6 44.8 28.6 41.6 41.3 130.8 19.4 30.1 32.7 1074.7 41.7 240.4 79.0 68.6 323.0 361.4 412.2 338.4 514.5 428.4 378.9 404.5 309.1 417.2 329.2 334.0 384.0 62.8 134.6 67.5 110.7 35.9 144.5 103.5 63.0 101.3 157.7 125.2 59.9 36.1 81.5 91.9 244.6 70.9 68.6 55.6 118.2 29.4 154.4 35.8 96.4 74.3 68.1 99.8 85.8 398.8 117.1 105.6 96.7 60.1 129.2 77.3 71.4 85.6 81.3 143.7 82.4 372.7 83.5 122.1 178.3 110.8 71.2 79.2 151.4 113.8 100.2 178.0 150.3 42.2 200.6 294.8 103.3 82.0 89.9 94.8 79.4 94.5 55.9 156.0 97.6 78.9 53.1 78.6 194.7 133.5 85.9 146.2 86.5 48.8 51.7 96.5 99.8 RTN4 "ASY, KIAA0886, NOGO, NSP-CL" ENSG00000115310 "Reticulon 4" Q9NQC3 2 54972187-55112621 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Muller glia cells: 3547.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 95.8" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 1801.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005388, HPA023977" Supported Enhanced "Endoplasmic reticulum" NA NA 3400000 "Cluster 38: Basophils - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" "Endoplasmic reticulum" "CAB005388: AB_2285559, HPA023977: AB_2671391" "unprognostic (1.31e-2)" "unprognostic (1.71e-3)" "unprognostic (6.76e-2)" "unprognostic (1.28e-3)" "unprognostic (1.24e-3)" "prognostic unfavorable (1.00e-4)" "unprognostic (5.79e-2)" "unprognostic (1.84e-3)" "unprognostic (2.47e-1)" "unprognostic (1.97e-1)" "unprognostic (3.91e-3)" "unprognostic (4.38e-1)" "unprognostic (4.41e-2)" "unprognostic (1.29e-2)" "unprognostic (4.99e-2)" "unprognostic (1.27e-1)" "unprognostic (4.91e-2)" 586.2 302.7 376.3 150.9 461.9 115.4 253.1 465.9 534.3 118.0 297.1 186.9 236.2 153.9 176.5 217.9 130.0 196.8 166.0 411.8 431.6 442.5 551.9 211.8 83.6 498.6 456.5 132.0 122.7 236.7 84.0 177.3 524.8 223.9 179.2 640.6 127.1 183.4 996.0 252.9 292.5 246.4 440.8 110.3 124.0 78.6 453.2 87.1 130.7 777.9 88.2 291.2 147.9 591.2 402.9 285.3 273.3 71.7 908.4 845.0 153.2 1301.6 1097.4 393.5 365.7 235.5 371.7 87.1 673.8 889.9 657.7 355.6 181.5 524.4 596.2 248.3 139.4 120.3 159.6 376.6 1801.9 218.1 59.7 638.5 490.8 540.3 1041.9 792.3 751.3 215.6 249.8 195.0 1724.1 117.8 268.3 222.0 245.9 86.8 252.0 118.5 360.3 180.0 924.0 475.9 179.2 211.3 297.7 173.3 378.1 465.1 147.2 165.1 1074.9 764.8 326.1 304.8 756.5 118.0 103.4 56.1 778.7 247.9 630.1 95.8 9.5 27.5 9.2 11.6 7.6 6.8 14.7 8.2 9.2 3.8 24.1 10.2 15.6 41.1 19.0 13.7 37.6 9.9 376.3 461.9 465.9 534.3 411.8 431.6 498.6 456.5 524.8 440.8 453.2 591.2 451.4 176.3 203.4 201.4 102.3 1062.1 1456.6 367.0 225.9 644.6 297.6 260.6 182.0 243.1 251.0 676.8 379.5 529.6 173.6 408.6 291.6 559.7 459.7 316.6 264.6 308.0 222.1 98.2 454.5 323.4 611.9 421.9 98.4 324.7 150.4 161.5 181.3 633.4 669.1 425.7 370.4 280.5 231.9 339.0 578.4 266.6 167.4 371.7 341.5 215.5 396.4 3547.4 137.0 249.3 1334.3 571.2 309.7 226.1 81.6 921.4 897.1 678.3 233.6 540.0 216.9 420.5 324.6 382.7 90.1 247.1 1059.3 362.0 145.5 100.1 238.1 1226.5 SAMD8 "FLJ25082, SMSr" ENSG00000156671 "Sterile alpha motif domain containing 8" Q96LT4 10 75099586-75182123 "Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 19.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044402 Supported "Endoplasmic reticulum" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" "Endoplasmic reticulum" "HPA044402: " "unprognostic (4.32e-1)" "unprognostic (3.14e-1)" "unprognostic (3.24e-2)" "unprognostic (7.87e-2)" "unprognostic (3.37e-2)" "unprognostic (2.77e-2)" "unprognostic (1.61e-2)" "unprognostic (1.39e-1)" "unprognostic (5.29e-1)" "unprognostic (3.12e-2)" "unprognostic (2.70e-1)" "unprognostic (4.69e-2)" "unprognostic (4.16e-3)" "unprognostic (3.89e-2)" "unprognostic (3.76e-1)" "unprognostic (2.53e-1)" "unprognostic (9.26e-3)" 14.0 10.8 17.1 7.2 22.8 17.0 10.4 20.8 18.7 14.8 10.3 7.2 6.1 11.1 7.2 15.6 10.7 9.2 11.3 17.1 17.8 7.3 7.5 10.1 6.9 23.4 24.9 13.6 5.1 9.6 9.2 11.5 22.5 8.1 4.9 22.6 7.7 8.0 27.1 7.1 6.8 10.1 23.6 7.9 5.6 15.2 21.0 6.3 7.8 14.7 6.1 9.5 12.9 29.7 8.7 7.8 12.7 10.0 28.1 25.8 15.1 14.8 29.9 9.1 11.7 12.8 12.4 5.9 9.4 14.3 10.5 15.3 6.8 11.3 15.9 7.2 8.3 2.6 8.0 8.6 15.6 2.7 6.8 24.4 11.2 18.0 24.8 24.6 14.1 6.7 5.6 10.4 21.0 6.1 5.1 4.1 5.7 6.4 23.9 4.4 10.6 2.8 10.3 7.8 1.8 8.7 13.9 17.8 15.1 13.6 7.4 3.1 22.6 10.5 13.7 12.6 10.4 6.9 6.9 6.0 16.4 7.0 6.7 3.1 3.7 2.5 2.9 4.8 1.8 5.5 3.2 3.4 3.4 5.9 2.7 3.1 19.2 4.0 6.6 3.8 3.0 1.3 17.1 22.8 20.8 18.7 17.1 17.8 23.4 24.9 22.5 23.6 21.0 29.7 24.6 9.6 12.5 25.1 25.0 42.3 28.1 34.2 23.9 20.9 21.4 11.3 26.7 10.0 26.5 14.7 14.6 10.4 18.1 10.0 0.0 10.9 47.6 17.3 29.8 24.3 23.4 4.4 50.9 10.2 12.5 29.4 10.2 23.1 12.7 18.5 23.2 10.9 13.2 18.5 37.2 3.3 26.4 16.3 48.4 10.9 25.1 27.8 12.4 35.6 27.8 20.5 12.3 38.2 77.1 16.3 11.4 25.2 22.2 22.3 11.8 7.7 35.4 32.7 32.9 30.9 23.9 54.7 24.3 42.9 42.9 68.0 20.2 12.4 5.2 40.3 SAR1A "SAR1, Sara, SARA1" ENSG00000079332 "Secretion associated Ras related GTPase 1A" Q9NR31 10 70147289-70170523 "Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006923, CAB022545, HPA048368" Supported Supported "Endoplasmic reticulum" NA NA 660000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 10: Non-specific - Unknown function" "Endoplasmic reticulum" "CAB022545: , HPA006923: AB_1856577, HPA048368: AB_2680373" "unprognostic (3.77e-2)" "unprognostic (7.13e-2)" "unprognostic (3.08e-3)" "unprognostic (3.13e-2)" "unprognostic (5.35e-2)" "prognostic unfavorable (7.00e-5)" "prognostic unfavorable (4.04e-4)" "unprognostic (1.60e-2)" "unprognostic (1.00e-1)" "unprognostic (1.02e-2)" "unprognostic (4.06e-2)" "unprognostic (2.06e-1)" "unprognostic (2.38e-3)" "unprognostic (1.76e-1)" "unprognostic (4.80e-2)" "unprognostic (1.10e-2)" "unprognostic (7.13e-2)" 77.1 52.8 41.8 38.4 43.5 163.2 48.1 45.1 45.7 43.1 53.3 39.1 26.6 41.0 47.0 41.4 37.3 35.0 44.8 43.8 48.3 43.3 70.2 51.4 36.7 42.8 44.9 41.0 33.9 44.2 37.9 76.0 44.0 38.9 35.5 42.0 39.9 38.9 51.1 38.5 34.5 49.7 47.3 40.7 37.9 23.5 48.4 33.2 39.8 56.3 38.4 45.8 36.2 52.1 85.8 56.3 75.7 131.9 246.1 143.1 61.1 128.3 154.4 115.6 140.0 169.7 78.2 74.4 67.1 153.7 52.8 96.6 94.5 75.9 111.6 103.9 44.3 54.1 65.8 82.5 112.4 86.7 56.6 155.9 68.4 76.4 133.2 119.0 63.8 55.9 68.7 105.9 110.0 60.0 73.8 72.6 65.2 55.6 141.3 70.8 84.4 42.5 88.7 69.7 42.6 73.8 98.0 134.6 72.2 66.8 65.8 59.7 88.6 63.7 94.3 92.2 91.3 72.3 141.3 114.0 84.9 111.7 48.7 75.5 63.5 74.0 88.0 80.9 94.8 47.7 68.5 85.9 58.5 38.6 65.7 88.7 67.9 103.3 72.9 44.8 53.2 95.9 41.8 43.5 45.1 45.7 43.8 48.3 42.8 44.9 44.0 47.3 48.4 52.1 88.4 128.2 110.2 6.8 53.5 235.7 138.0 120.2 25.0 38.6 99.2 62.4 74.7 57.2 105.3 49.7 33.3 120.6 109.8 51.6 54.8 78.4 3.0 52.3 85.8 85.2 42.7 46.1 21.2 77.3 199.0 127.8 23.9 89.7 53.2 46.3 69.7 114.1 101.0 26.9 22.2 72.1 65.1 51.2 208.9 5.6 54.7 68.1 113.8 21.5 58.4 61.9 75.2 16.1 26.4 78.8 56.2 58.6 97.7 141.4 59.1 95.9 67.1 33.4 78.9 73.7 158.8 64.1 51.8 37.2 248.8 238.9 86.3 45.2 53.2 175.2 SAR1B SARA2 ENSG00000152700 "Secretion associated Ras related GTPase 1B" Q9Y6B6 5 134601149-134649271 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 413.3;Hepatocytes: 267.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006923, HPA048368" Supported Approved "Endoplasmic reticulum" NA NA 430000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 16: U-266 - Nucleosome" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Endoplasmic reticulum" "HPA006923: AB_1856577, HPA048368: AB_2680373" "unprognostic (6.14e-2)" "unprognostic (7.33e-2)" "unprognostic (5.32e-2)" "prognostic favorable (7.11e-4)" "unprognostic (1.23e-1)" "unprognostic (5.92e-2)" "prognostic favorable (6.59e-4)" "unprognostic (1.88e-2)" "unprognostic (1.69e-1)" "unprognostic (2.69e-1)" "unprognostic (7.32e-2)" "unprognostic (6.87e-2)" "unprognostic (2.45e-1)" "unprognostic (5.69e-2)" "unprognostic (4.66e-2)" "unprognostic (7.50e-3)" "unprognostic (1.87e-2)" 30.9 46.4 27.5 24.2 40.6 26.0 35.8 40.8 41.7 27.3 40.6 40.9 68.5 14.9 34.9 36.0 17.7 28.2 46.8 31.0 37.5 57.1 163.9 19.7 24.4 43.9 40.5 13.5 32.8 64.9 24.7 20.7 44.7 38.7 36.5 20.3 36.3 29.7 147.5 16.8 69.7 26.7 40.3 20.0 43.4 66.0 35.9 22.7 29.7 140.6 33.6 36.2 20.3 53.9 57.8 49.6 36.0 81.3 111.6 53.4 48.3 95.4 80.0 84.1 127.9 84.3 79.7 31.9 78.3 98.6 116.6 52.1 62.8 92.5 108.0 73.6 37.0 33.6 78.0 81.5 91.7 29.1 44.7 60.4 57.8 97.7 82.7 42.3 64.1 40.9 44.3 71.9 87.0 85.3 38.6 43.6 12.7 70.7 34.4 33.7 62.7 70.2 61.7 91.2 36.8 16.0 67.2 36.1 71.4 47.2 74.2 35.5 51.7 72.8 44.0 66.7 72.3 90.0 215.4 58.7 56.2 55.7 81.6 22.2 70.5 55.0 42.3 71.2 52.9 52.7 48.2 49.7 64.0 34.7 42.9 41.6 25.5 35.8 80.5 43.6 77.1 71.3 27.5 40.6 40.8 41.7 31.0 37.5 43.9 40.5 44.7 40.3 35.9 53.9 49.3 32.1 36.9 21.5 45.6 37.6 44.0 112.9 22.2 30.4 56.0 35.7 86.7 61.5 102.6 57.0 41.7 33.1 44.5 77.0 56.7 47.6 413.3 43.0 51.3 35.3 27.6 44.2 31.6 83.9 43.5 46.1 68.3 45.8 26.6 28.3 38.9 267.7 52.8 33.7 32.8 55.2 89.5 52.9 56.6 76.9 36.7 47.1 64.0 20.6 38.3 41.8 20.6 29.7 66.5 60.4 36.2 44.8 165.8 75.1 210.7 121.4 99.8 40.3 19.7 41.2 47.7 106.8 47.3 51.1 51.1 115.2 47.0 43.0 46.3 96.5 SCARA3 "APC7, CSR, CSR1, MSLR1, MSRL1" ENSG00000168077 "Scavenger receptor class A member 3" Q6AZY7 8 27633868-27676776 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 136.5" "Cell type enhanced" "Detected in many" "Astrocytes: 238.6;Collecting duct cells: 66.2;Cytotrophoblasts: 45.8;Muller glia cells: 52.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 179.9;HeLa: 203.2;HUVEC TERT2: 140.1;U-2 OS: 120.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029861, HPA047386" Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 64: Astrocytes - Nervous system maintenance" "Endoplasmic reticulum" "HPA029861: AB_2673225, HPA047386: AB_2680024" "unprognostic (2.24e-1)" "unprognostic (5.36e-3)" "unprognostic (2.68e-3)" "unprognostic (1.36e-1)" "unprognostic (1.48e-2)" "unprognostic (1.17e-1)" "unprognostic (4.31e-1)" "unprognostic (1.60e-1)" "unprognostic (3.58e-2)" "unprognostic (1.45e-1)" "unprognostic (3.80e-1)" "unprognostic (1.66e-1)" "unprognostic (3.41e-2)" "unprognostic (1.78e-2)" "unprognostic (4.95e-2)" "unprognostic (6.31e-3)" "unprognostic (6.03e-3)" 23.8 7.2 53.4 15.7 58.6 0.0 17.6 55.6 57.8 58.7 29.9 34.5 5.0 87.9 9.5 23.7 86.8 30.5 13.9 50.3 68.1 11.3 3.9 15.2 13.4 136.5 89.5 13.8 4.1 1.5 9.6 19.5 79.2 25.6 8.5 8.8 35.7 66.5 2.6 17.5 15.4 68.1 80.3 2.8 14.7 3.2 79.2 15.9 51.3 8.0 23.0 31.1 20.7 71.4 1.8 61.0 9.4 0.2 49.9 179.9 40.0 23.8 38.2 25.8 19.1 22.7 15.8 0.0 52.7 50.3 21.1 44.5 0.1 44.9 12.7 0.2 5.1 17.8 203.2 0.8 5.3 0.0 0.1 75.6 2.9 40.2 2.3 35.0 140.1 4.6 0.0 0.2 15.0 11.8 0.2 0.1 12.3 0.0 22.3 0.1 0.0 0.3 8.2 27.4 0.2 5.9 5.7 32.0 0.1 4.8 31.1 0.5 49.9 20.7 120.1 77.2 12.8 0.1 0.1 0.2 35.7 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.4 58.6 55.6 57.8 50.3 68.1 136.5 89.5 79.2 80.3 79.2 71.4 2.3 0.0 0.5 238.6 0.0 3.6 16.2 4.8 14.8 1.0 12.6 19.8 2.2 8.6 6.0 66.2 0.0 45.8 0.6 0.1 0.0 0.4 2.9 3.8 10.1 6.4 0.0 0.0 38.4 0.8 20.4 25.1 1.5 2.0 0.0 5.3 15.4 0.4 4.7 0.0 30.4 0.1 0.0 0.3 2.1 1.3 15.8 0.5 17.8 21.5 0.6 52.4 0.0 19.1 18.1 2.2 0.1 6.4 0.0 5.4 0.0 0.0 6.5 1.5 6.6 1.8 14.7 0.2 1.5 6.2 3.8 8.2 0.3 1.9 0.3 10.3 SCD "FADS5, SCDOS" ENSG00000099194 "Stearoyl-CoA desaturase" O00767 10 100347233-100364826 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 1233.7;brain: 839.9;liver: 583.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 389.6;Granulosa cells: 187.3;Hepatocytes: 840.3;Oligodendrocytes: 451.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "ASC diff: 2534.2;CAPAN-2: 1824.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA012107, HPA063921" Approved Enhanced "Endoplasmic reticulum" No Yes "Cluster 7: Monocytes - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "HPA012107: AB_1856610, HPA063921: AB_2685154" "unprognostic (2.10e-1)" "unprognostic (2.62e-3)" "unprognostic (7.86e-2)" "unprognostic (5.19e-2)" "unprognostic (1.24e-1)" "unprognostic (6.16e-2)" "unprognostic (1.13e-1)" "unprognostic (3.88e-2)" "unprognostic (6.53e-2)" "unprognostic (2.72e-1)" "unprognostic (1.47e-1)" "unprognostic (1.69e-1)" "prognostic unfavorable (7.56e-5)" "unprognostic (7.18e-2)" "unprognostic (3.27e-1)" "unprognostic (4.73e-2)" "prognostic unfavorable (7.79e-5)" 1233.7 131.2 408.7 25.7 525.8 23.0 261.5 535.7 522.1 43.2 156.6 42.9 93.1 15.4 25.5 107.8 5.0 28.7 47.1 349.1 457.5 18.5 583.8 142.8 17.2 775.0 508.9 49.6 22.6 79.5 10.3 19.9 637.8 100.1 39.7 17.9 112.6 11.2 6.1 27.0 36.0 15.9 574.4 15.3 25.2 51.8 538.7 18.4 13.0 7.2 21.0 22.5 41.9 839.9 411.2 373.3 777.6 536.4 2534.2 1449.4 158.2 43.4 948.3 101.6 536.6 323.8 1824.4 173.3 33.7 102.2 461.8 716.4 433.7 1549.5 88.9 59.4 179.6 97.5 219.3 653.4 488.4 136.9 100.9 795.5 459.4 395.0 688.9 273.1 196.2 375.3 275.4 513.3 41.7 646.8 155.9 163.3 270.7 120.7 106.3 72.6 287.4 550.4 443.8 455.3 48.9 185.3 85.8 399.7 834.9 224.2 447.7 291.3 79.0 10.0 115.9 9.1 89.8 141.4 81.5 262.9 184.4 416.0 65.9 0.0 0.8 0.0 1.4 1.6 2.3 0.6 0.5 0.7 2.7 0.9 0.4 1.3 0.1 1.4 0.0 1.5 0.0 1.2 408.7 525.8 535.7 522.1 349.1 457.5 775.0 508.9 637.8 574.4 538.7 839.9 3.8 54.5 389.6 34.0 15.7 3.7 4.5 121.8 0.6 6.5 16.1 6.2 11.2 28.6 66.2 0.0 6.2 3.0 4.7 21.5 0.0 14.6 52.6 13.9 9.0 12.5 25.8 15.8 4.8 67.9 71.7 15.9 25.0 26.9 6.3 187.3 32.9 840.3 34.1 26.9 5.2 16.4 52.9 113.5 4.2 93.0 3.7 21.2 58.7 8.4 10.2 11.9 2.1 18.6 451.5 29.6 2.7 1.5 3.7 31.4 16.2 4.9 31.0 6.2 0.0 3.6 25.7 2.0 1.2 26.7 2.3 17.4 6.6 97.8 38.9 8.2 SEC61A1 ENSG00000058262 "SEC61 translocon subunit alpha 1" P61619 3 128051641-128071683 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Protein transport, Translocation, Transport" Chaperone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022076 Supported "Endoplasmic reticulum" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Endoplasmic reticulum" "CAB022076: " "unprognostic (1.84e-1)" "unprognostic (8.00e-2)" "unprognostic (8.21e-2)" "prognostic favorable (7.82e-4)" "unprognostic (2.13e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (1.07e-6)" "unprognostic (2.84e-2)" "unprognostic (4.67e-1)" "unprognostic (1.23e-1)" "unprognostic (3.85e-2)" "unprognostic (1.43e-1)" "prognostic unfavorable (6.84e-9)" "unprognostic (2.73e-2)" "unprognostic (3.18e-2)" "unprognostic (8.33e-2)" "unprognostic (2.51e-2)" 82.1 100.7 31.3 88.3 33.4 79.5 75.3 33.5 34.7 144.5 52.4 90.7 81.9 88.9 128.9 88.7 78.1 81.7 74.2 32.3 39.6 64.6 134.8 93.3 60.2 40.9 37.6 67.3 272.1 111.7 93.5 112.8 36.0 90.0 90.0 37.0 176.3 97.0 70.5 66.9 75.8 110.7 36.6 73.7 105.5 38.8 46.6 61.4 104.8 59.3 80.6 97.0 68.7 35.8 272.8 136.5 132.0 240.3 367.9 317.3 256.9 426.9 470.8 349.0 371.2 259.1 186.9 184.7 259.5 534.8 266.2 232.6 209.0 291.3 334.2 168.1 126.2 213.5 143.5 273.6 542.9 264.1 225.9 348.1 345.4 329.3 422.4 265.0 314.3 122.2 136.9 415.3 412.8 237.7 135.1 87.5 184.6 231.6 202.8 144.2 125.5 349.8 181.4 229.3 155.8 162.4 216.0 193.5 270.7 152.0 184.2 215.1 327.3 278.3 164.7 333.7 201.4 386.6 210.6 265.8 456.3 166.2 369.1 160.3 88.6 67.0 89.0 79.6 120.0 43.8 62.9 78.2 82.6 26.1 38.8 46.2 22.5 65.0 84.2 114.0 45.1 116.9 31.3 33.4 33.5 34.7 32.3 39.6 40.9 37.6 36.0 36.6 46.6 35.8 31.9 32.1 33.1 18.6 46.6 37.0 25.7 44.4 30.7 17.0 63.5 41.3 15.0 37.1 43.3 49.7 35.5 64.3 59.2 107.2 3.9 81.0 42.2 28.2 72.9 45.9 73.6 19.5 12.6 154.5 136.3 57.4 77.5 68.6 26.0 55.6 49.6 118.2 75.9 26.9 18.5 150.8 38.7 34.8 32.1 25.7 41.0 38.2 33.8 26.2 32.1 22.4 28.8 19.1 17.2 104.9 50.2 43.6 192.8 69.6 63.5 26.8 31.0 15.5 32.9 25.6 47.2 12.3 18.4 42.5 29.5 127.9 32.4 52.6 100.4 44.6 SEC61B ENSG00000106803 "SEC61 translocon subunit beta" P60468 9 99222064-99230615 "Predicted membrane proteins, Transporters" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 1573.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA049407 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 65: Plasmacytoid DCs - Unknown function" "Endoplasmic reticulum" "HPA049407: AB_2680750" "unprognostic (1.11e-1)" "unprognostic (5.99e-3)" "unprognostic (3.46e-1)" "prognostic favorable (1.26e-5)" "unprognostic (1.96e-1)" "unprognostic (4.54e-2)" "unprognostic (1.21e-3)" "unprognostic (1.09e-1)" "unprognostic (6.67e-2)" "unprognostic (1.87e-2)" "unprognostic (2.90e-2)" "unprognostic (7.07e-2)" "unprognostic (1.22e-1)" "unprognostic (1.84e-1)" "unprognostic (1.57e-1)" "unprognostic (6.87e-2)" "unprognostic (2.75e-1)" 173.5 235.8 101.0 154.7 104.0 255.5 153.4 104.3 120.8 179.4 105.3 139.3 155.0 167.7 259.4 169.8 155.0 129.8 106.7 104.4 110.8 213.7 465.3 169.0 184.0 104.5 102.1 158.5 546.0 145.9 209.5 98.3 105.8 168.0 102.8 48.5 347.7 124.3 61.0 122.5 132.9 106.3 106.8 173.1 186.5 76.4 103.8 188.8 179.8 44.2 146.7 148.8 139.1 111.6 226.5 213.3 244.1 243.7 234.5 296.0 293.9 327.6 335.8 299.9 259.2 307.3 172.6 305.3 244.3 298.7 328.9 272.0 171.9 259.5 143.1 325.4 238.7 160.7 200.7 440.3 509.9 278.9 198.3 268.0 389.4 237.3 210.3 268.1 369.8 246.7 255.0 581.1 285.6 407.7 255.6 404.9 196.3 533.9 497.7 244.2 207.7 398.1 332.3 158.3 252.7 179.2 183.6 421.1 441.5 190.8 163.4 378.6 265.1 215.3 260.0 363.5 277.7 312.0 226.6 200.7 359.3 176.6 145.6 875.3 460.3 453.3 354.6 387.9 480.8 356.5 389.3 360.4 481.0 257.1 242.9 267.7 388.5 325.7 350.8 1661.8 388.0 525.0 101.0 104.0 104.3 120.8 104.4 110.8 104.5 102.1 105.8 106.8 103.8 111.6 255.6 102.5 206.1 18.3 370.9 395.8 308.3 712.8 213.9 59.3 499.1 530.7 55.5 271.7 416.8 200.5 31.3 336.6 605.9 239.9 633.9 498.6 184.2 274.7 410.2 286.1 302.0 226.8 16.2 792.5 577.9 343.2 214.1 391.3 214.8 258.8 213.8 822.0 509.8 53.8 15.5 534.0 406.9 295.3 553.2 51.8 328.0 316.3 496.2 17.8 1573.9 197.3 284.2 15.6 25.9 633.4 280.0 304.3 1190.6 654.2 290.3 767.6 331.4 81.5 138.1 237.1 404.7 218.4 171.0 337.5 443.4 553.8 270.1 333.0 334.0 501.5 SEC63 "DNAJC23, ERdj2, PRO2507, SEC63L" ENSG00000025796 "SEC63 homolog, protein translocation regulator" Q9UGP8 6 107867756-107958208 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Protein transport, Transport" Chaperone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Theca cells: 354.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053295, HPA060535" Supported Supported "Endoplasmic reticulum" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" "Endoplasmic reticulum" "HPA053295: AB_2682105, HPA060535: AB_2684312" "prognostic unfavorable (3.32e-4)" "prognostic unfavorable (4.01e-4)" "unprognostic (4.08e-1)" "unprognostic (1.56e-1)" "unprognostic (4.36e-3)" "unprognostic (1.51e-2)" "unprognostic (8.33e-3)" "unprognostic (1.24e-1)" "unprognostic (1.80e-1)" "unprognostic (1.04e-1)" "unprognostic (3.27e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (6.16e-4)" "unprognostic (2.35e-1)" "unprognostic (1.93e-1)" "unprognostic (1.56e-1)" "unprognostic (4.41e-2)" 27.5 33.0 11.6 22.0 14.3 32.9 23.3 14.4 12.9 30.2 25.7 19.2 16.8 25.2 29.6 19.5 21.8 22.0 19.0 12.4 15.3 20.0 46.6 21.7 16.7 13.3 12.0 40.4 61.2 31.7 14.4 20.9 14.2 27.7 18.6 21.2 77.8 23.3 14.3 15.5 18.0 22.2 12.3 16.1 23.1 33.0 12.1 22.6 52.1 14.1 17.3 21.8 14.0 17.7 28.5 17.1 46.0 57.6 47.1 55.2 41.4 59.2 65.0 27.8 39.2 30.8 34.6 52.8 49.4 53.7 34.4 40.9 32.3 38.3 42.5 63.8 35.7 57.2 25.2 31.6 73.2 65.9 32.5 43.5 61.4 44.5 97.6 50.0 39.3 31.7 48.5 82.8 57.7 22.7 20.6 29.5 36.4 30.0 18.1 65.2 54.4 43.7 33.5 37.1 40.3 45.7 32.9 48.8 59.1 31.2 34.9 95.8 42.5 41.6 25.8 42.2 46.6 31.4 25.0 52.9 45.9 56.4 48.7 5.6 5.2 5.0 4.8 4.7 7.5 4.4 3.9 3.9 5.4 4.0 4.3 3.4 1.7 7.1 9.8 6.9 2.2 3.5 11.6 14.3 14.4 12.9 12.4 15.3 13.3 12.0 14.2 12.3 12.1 17.7 55.6 118.6 143.3 38.2 64.4 85.0 70.5 90.9 42.7 57.7 67.8 54.2 78.8 81.5 125.5 53.3 39.6 80.8 71.6 39.2 11.7 86.0 40.3 48.7 102.8 61.6 53.5 31.5 52.5 125.4 96.4 107.1 46.9 54.8 68.9 84.8 59.6 126.7 62.7 47.1 50.8 80.0 83.4 56.7 78.9 23.9 106.2 54.8 80.0 42.2 54.3 61.0 59.8 60.3 64.8 81.9 53.5 118.8 144.6 91.1 37.2 38.4 116.7 49.9 46.0 108.2 77.2 143.1 75.0 44.7 80.0 91.0 52.3 354.8 60.8 73.8 SELENOS "AD-015, MGC2553, SBBI8, SELS, SEPS1, VIMP" ENSG00000131871 "Selenoprotein S" Q9BQE4 15 101270817-101277500 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 229.2;Glandular and luminal cells: 211.7;Pancreatic endocrine cells: 226.1;Syncytiotrophoblasts: 303.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "plasmacytoid DC: 606.9" "Lineage enriched" "Detected in all" 5 "dendritic cells: 606.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010025 Approved Enhanced "Endoplasmic reticulum" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Endoplasmic reticulum" "HPA010025: AB_1079900" "unprognostic (1.90e-1)" "unprognostic (4.03e-2)" "unprognostic (1.06e-1)" "prognostic favorable (1.33e-4)" "unprognostic (2.42e-2)" "unprognostic (3.74e-3)" "unprognostic (3.18e-2)" "unprognostic (1.98e-1)" "unprognostic (9.83e-2)" "prognostic favorable (5.19e-4)" "unprognostic (2.42e-3)" "unprognostic (4.42e-1)" "unprognostic (1.11e-1)" "unprognostic (1.52e-1)" "unprognostic (1.67e-1)" "unprognostic (1.44e-1)" "unprognostic (2.66e-2)" 65.6 75.4 30.6 48.4 32.8 50.6 55.0 33.8 39.8 50.1 39.7 82.4 80.0 41.9 75.5 55.6 44.6 45.5 66.3 29.8 32.7 48.7 84.7 59.6 49.2 35.2 33.2 41.6 103.7 51.1 44.5 57.6 35.3 53.6 87.2 28.7 73.8 49.1 71.0 48.4 82.2 42.9 33.7 58.7 67.2 92.7 32.4 24.1 55.8 48.7 53.1 60.7 45.3 36.3 45.3 68.8 61.2 54.5 129.8 91.1 52.4 136.4 100.2 89.8 90.2 82.3 105.0 33.6 49.6 117.5 150.8 125.1 66.6 59.7 58.6 63.5 91.8 57.2 62.5 86.8 206.5 43.5 63.9 80.2 166.3 60.3 177.7 70.7 68.1 44.3 58.3 369.0 97.4 71.7 31.7 67.6 46.8 169.9 45.7 41.6 50.1 74.7 90.7 104.2 34.5 88.5 93.0 85.7 193.8 79.9 64.0 96.2 73.6 84.0 57.1 116.4 103.3 272.5 246.3 49.9 92.2 50.8 104.2 134.4 66.4 81.2 94.1 84.0 91.1 62.2 71.4 101.1 58.6 51.4 53.7 79.6 23.1 95.6 100.1 606.9 71.4 63.7 30.6 32.8 33.8 39.8 29.8 32.7 35.2 33.2 35.3 33.7 32.4 36.3 164.0 118.6 108.6 0.0 47.8 0.0 0.0 0.0 0.0 0.0 172.5 129.4 0.0 0.0 64.4 154.5 0.0 125.9 87.7 0.0 31.3 183.9 0.0 127.0 165.2 53.3 0.0 0.0 0.0 189.3 229.2 91.6 0.0 211.7 30.3 53.5 0.0 0.0 120.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 66.4 0.0 0.0 92.0 0.0 0.0 0.0 0.0 226.1 0.0 0.0 101.0 0.0 0.0 73.0 56.9 0.0 0.0 0.0 78.5 0.0 0.0 0.0 0.0 303.7 40.4 100.9 0.0 0.0 SERP1 "FLJ43424, RAMP4" ENSG00000120742 "Stress associated endoplasmic reticulum protein 1" Q9Y6X1 3 150541998-150603228 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 542.5;U-266/70: 735.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038970 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "HPA038970: AB_2676296" "unprognostic (8.81e-3)" "unprognostic (2.35e-3)" "unprognostic (1.91e-1)" "unprognostic (7.29e-3)" "unprognostic (3.99e-2)" "unprognostic (1.01e-1)" "unprognostic (1.57e-2)" "unprognostic (2.35e-3)" "unprognostic (6.16e-2)" "unprognostic (1.77e-3)" "prognostic unfavorable (1.03e-5)" "unprognostic (1.12e-1)" "unprognostic (1.61e-3)" "unprognostic (2.55e-2)" "unprognostic (2.75e-2)" "unprognostic (4.75e-2)" "unprognostic (1.78e-1)" 74.6 94.0 52.9 64.4 56.5 86.8 103.9 51.5 67.7 104.3 55.1 78.5 63.4 51.0 158.0 80.6 80.2 48.2 39.0 54.2 56.1 73.9 157.7 82.3 66.1 54.3 51.2 80.7 255.6 57.2 84.6 60.2 53.2 92.4 67.8 26.1 185.5 69.8 16.9 52.8 64.2 45.0 56.1 87.8 114.8 37.5 56.0 66.4 113.3 17.0 74.5 64.6 64.2 58.8 216.1 46.3 68.9 52.5 99.7 116.0 152.9 150.4 98.7 82.2 96.5 121.6 93.7 175.8 274.8 111.7 67.7 102.2 113.6 79.5 108.6 104.7 93.3 187.1 38.4 123.9 193.9 170.8 117.4 69.6 139.4 47.7 236.7 89.2 97.7 118.1 92.7 241.0 70.8 95.3 144.5 143.3 128.1 138.5 115.1 181.2 52.5 542.5 100.4 69.7 116.8 99.3 57.8 128.4 244.5 83.2 112.8 165.0 93.8 38.9 69.6 84.4 117.0 735.1 230.5 236.0 70.9 165.2 36.8 347.2 410.6 375.2 237.4 399.6 304.5 239.7 250.3 238.5 317.6 222.1 244.0 227.3 299.9 188.5 456.8 321.1 268.0 508.0 52.9 56.5 51.5 67.7 54.2 56.1 54.3 51.2 53.2 56.1 56.0 58.8 168.0 67.3 162.7 66.0 468.4 538.0 677.4 277.8 363.7 74.5 500.8 451.2 44.5 158.7 246.5 172.9 58.4 284.6 337.7 351.1 365.9 231.3 361.1 246.5 198.9 189.5 254.0 157.5 51.6 304.3 553.8 213.0 218.2 359.7 219.7 135.4 249.5 480.7 373.5 42.1 48.0 563.2 168.9 662.6 477.8 627.0 219.6 512.6 348.6 25.3 558.1 174.5 279.1 63.3 60.6 349.0 564.2 190.3 923.0 744.8 326.1 293.7 218.5 69.6 111.7 98.1 192.4 208.0 91.3 347.4 592.7 944.7 335.5 94.2 404.3 1101.9 SERP2 "bA269C23.1, C13orf21" ENSG00000151778 "Stress associated endoplasmic reticulum protein family member 2" Q8N6R1 13 44373665-44397714 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 87.7;choroid plexus: 53.7" "Group enriched" "Detected in many" 11 "Early spermatids: 577.8;Late spermatids: 237.7" "Cancer enhanced" "Detected in many" "glioma: 6.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.6" "Lineage enhanced" "Detected in single" "granulocytes: 2.6" "Cell line enhanced" "Detected in some" "LHCN-M2: 3.7;SH-SY5Y: 5.1;U-2197: 4.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038970 Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 18: U-2197 - ECM organization" "Cluster 34: Spermatids - Unknown function" "Endoplasmic reticulum" "HPA038970: AB_2676296" "unprognostic (6.55e-2)" "unprognostic (1.55e-1)" "unprognostic (4.10e-2)" "unprognostic (2.06e-1)" "unprognostic (9.62e-2)" "unprognostic (1.72e-2)" "unprognostic (2.85e-1)" "unprognostic (3.48e-2)" "unprognostic (1.51e-1)" "unprognostic (2.12e-1)" "unprognostic (1.34e-3)" "unprognostic (1.12e-2)" "prognostic favorable (1.94e-4)" "unprognostic (1.48e-1)" "unprognostic (6.60e-2)" "unprognostic (1.32e-1)" "unprognostic (7.89e-2)" 1.2 2.0 67.6 1.0 70.7 0.0 2.6 60.7 87.7 2.7 53.7 3.9 2.9 4.0 9.0 0.8 2.3 0.9 18.8 71.5 67.0 3.3 1.2 1.1 1.4 63.4 66.0 4.7 1.7 1.3 8.5 0.3 65.0 3.5 1.1 14.2 1.1 3.8 2.1 0.6 2.0 2.0 61.1 0.4 2.7 27.3 66.7 1.9 1.2 0.4 1.2 2.0 2.0 68.4 0.0 0.0 2.1 0.0 0.3 1.8 0.0 0.4 0.6 2.3 1.5 0.0 0.0 0.0 1.8 1.7 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.4 0.0 0.1 1.9 0.0 0.0 0.3 0.0 1.6 0.0 0.4 0.3 0.0 0.0 0.0 3.7 0.0 0.0 0.2 2.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 2.4 5.1 0.0 0.2 0.0 0.4 0.0 0.0 0.5 0.0 0.1 4.7 0.0 0.0 0.1 0.0 1.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 67.6 70.7 60.7 87.7 71.5 67.0 63.4 66.0 65.0 61.1 66.7 68.4 4.0 0.0 1.5 19.6 0.1 1.8 3.7 1.9 4.6 21.0 12.0 7.2 20.0 4.3 1.0 9.2 14.6 2.5 1.1 2.9 17.6 11.3 577.8 0.7 4.6 3.9 14.4 0.8 34.6 12.9 2.5 10.3 0.5 1.2 17.8 7.8 1.4 6.2 0.2 15.2 29.8 4.0 0.0 0.0 1.1 237.7 13.1 0.7 12.4 9.4 0.6 25.0 1.0 13.0 27.1 6.3 1.7 19.2 0.1 3.4 3.9 8.9 1.3 23.3 26.3 15.1 10.0 8.5 12.5 0.4 1.0 2.1 1.8 4.6 4.4 3.2 SERPINH1 "CBP1, CBP2, colligen, HSP47, SERPINH2" ENSG00000149257 "Serpin family H member 1" P50454 11 75562056-75572783 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Stress response" Chaperone "Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 473.6;Endometrial stromal cells: 273.3;Extravillous trophoblasts: 342.1;Fibroblasts: 287.6;Smooth muscle cells: 295.1" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebral cortex: 291.0" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 1018.3;fHDF/TERT166: 1215.2;HHSteC: 1029.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004441, HPA029198" Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" NA Yes 920000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB004441: AB_627757, HPA029198: AB_10601712" "unprognostic (3.80e-1)" "prognostic unfavorable (2.10e-4)" "unprognostic (5.93e-2)" "unprognostic (2.81e-3)" "unprognostic (3.25e-2)" "prognostic unfavorable (1.85e-4)" "unprognostic (2.39e-2)" "unprognostic (1.72e-3)" "unprognostic (2.35e-2)" "unprognostic (7.40e-2)" "unprognostic (1.57e-2)" "unprognostic (2.54e-2)" "prognostic unfavorable (3.22e-15)" "unprognostic (2.75e-2)" "unprognostic (1.27e-1)" "unprognostic (3.93e-2)" "unprognostic (1.96e-2)" 214.1 101.9 46.2 106.5 50.4 3.7 107.1 51.1 291.0 137.7 66.7 95.2 23.2 160.7 27.6 41.7 119.4 72.1 159.3 46.1 50.5 116.9 52.5 199.3 21.1 59.9 47.3 157.4 40.1 18.1 50.8 251.3 58.3 66.1 36.7 2.0 40.7 53.2 22.2 47.6 51.3 207.3 51.6 53.9 76.9 27.7 54.0 21.6 91.2 33.2 18.2 156.8 85.9 60.1 57.7 192.9 349.5 722.0 528.8 484.2 162.2 514.3 349.6 380.4 483.5 1018.3 294.1 0.4 470.2 1215.2 3.1 337.2 242.2 163.2 182.5 27.5 47.0 42.7 174.0 216.5 1029.5 0.9 7.2 580.9 165.2 365.0 121.3 475.5 530.8 22.1 90.5 16.1 182.5 457.6 1.2 74.8 315.6 215.8 50.7 29.3 200.3 48.8 95.6 107.8 9.1 119.1 326.9 59.7 102.0 539.6 144.4 72.7 284.6 388.6 324.6 270.6 128.3 23.1 25.5 6.1 168.0 0.2 535.6 4.1 1.1 0.1 6.0 1.1 5.2 0.9 3.9 4.0 4.4 0.7 4.0 3.3 0.2 5.9 0.1 3.7 3.5 2.1 46.2 50.4 51.1 291.0 46.1 50.5 59.9 47.3 58.3 51.6 54.0 60.1 142.3 38.5 32.0 4.9 2.9 81.8 473.6 56.5 74.0 5.3 28.3 39.5 36.6 14.3 21.0 25.8 58.4 217.0 3.2 33.0 0.0 64.5 2.9 21.8 273.3 194.9 61.1 11.4 0.4 11.9 342.1 287.6 15.3 33.0 9.5 144.1 124.9 9.9 94.2 6.7 0.2 55.7 22.4 5.7 110.0 6.0 164.4 43.6 44.4 18.7 9.8 14.3 8.2 1.0 0.5 22.5 24.3 120.7 6.5 139.8 12.4 22.8 11.9 1.2 92.1 31.4 295.1 29.3 23.0 14.1 44.5 165.8 68.8 79.8 62.8 73.4 SGPL1 SPL ENSG00000166224 "Sphingosine-1-phosphate lyase 1" O95470 10 70815948-70881184 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Lipid metabolism, Sphingolipid metabolism" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 112.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021125, HPA023086" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "Endoplasmic reticulum" "HPA021125: AB_1856803, HPA023086: AB_1856804" "unprognostic (1.14e-1)" "unprognostic (1.77e-1)" "unprognostic (1.15e-1)" "unprognostic (3.07e-2)" "unprognostic (2.13e-1)" "unprognostic (2.34e-1)" "unprognostic (7.60e-2)" "unprognostic (2.98e-2)" "unprognostic (2.88e-1)" "unprognostic (1.06e-1)" "unprognostic (1.70e-2)" "unprognostic (2.12e-1)" "unprognostic (9.52e-2)" "unprognostic (3.42e-1)" "unprognostic (2.14e-1)" "unprognostic (9.21e-2)" "unprognostic (4.68e-3)" 12.0 12.7 15.8 18.0 17.4 6.8 13.0 15.2 16.3 17.6 11.0 16.7 16.0 14.4 18.8 27.9 15.3 12.6 6.4 14.7 16.4 15.5 22.9 10.7 18.1 18.6 16.7 9.0 18.5 21.0 9.4 10.0 17.4 17.5 17.9 10.8 14.3 12.4 9.6 30.4 22.8 13.9 17.4 16.1 12.3 14.0 17.7 17.9 20.1 6.0 20.1 25.0 14.7 19.8 26.9 35.2 33.2 38.1 8.9 11.5 22.1 15.5 16.4 16.5 21.4 38.4 57.8 24.2 18.0 15.8 15.9 44.1 28.8 31.0 23.5 39.1 15.6 2.5 17.5 46.2 33.6 10.6 20.9 21.8 51.4 22.1 57.6 34.6 10.4 22.3 7.2 20.4 23.6 29.6 13.2 7.1 15.0 35.4 19.5 16.6 25.2 9.1 26.3 112.1 22.6 27.5 30.9 46.6 28.5 25.9 24.3 7.5 20.3 14.8 38.7 11.6 30.1 8.4 12.6 11.0 14.7 19.3 10.7 1.1 18.2 14.0 18.0 34.6 16.5 7.2 11.5 14.7 16.2 8.7 8.5 13.5 15.0 18.8 44.9 8.9 11.8 12.4 15.8 17.4 15.2 16.3 14.7 16.4 18.6 16.7 17.4 17.4 17.7 19.8 3.8 16.0 6.4 32.3 11.0 12.2 17.8 21.4 8.0 6.3 15.8 9.8 6.3 27.1 23.2 46.0 20.9 7.3 16.0 41.5 3.9 36.2 2.9 30.2 13.3 7.3 25.1 4.4 48.7 37.6 13.8 10.1 6.6 46.1 14.7 23.1 7.1 44.5 27.6 15.2 38.8 21.2 22.4 43.1 16.1 5.2 11.5 25.7 7.2 35.6 22.7 9.8 25.7 41.7 43.8 55.6 18.8 20.3 5.9 26.0 53.5 12.0 26.6 9.7 6.6 13.3 19.0 20.0 34.0 15.9 22.7 6.3 11.1 18.2 20.9 25.3 SLC16A14 "FLJ30794, MCT14" ENSG00000163053 "Solute carrier family 16 member 14" Q7RTX9 2 230034982-230068993 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 18.6" "Cell type enhanced" "Detected in many" "Adipocytes: 17.0;Excitatory neurons: 18.5;Inhibitory neurons: 21.1;Microglial cells: 45.0;Oligodendrocyte precursor cells: 13.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 24 "eosinophil: 11.3" "Lineage enriched" "Detected in single" 24 "granulocytes: 11.3" "Cell line enhanced" "Detected in many" "HL-60: 24.2;Karpas-707: 15.2;REH: 19.5;RPMI-8226: 17.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040518 Uncertain Approved "Endoplasmic reticulum" No No "Cluster 45: Eosinophils - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "HPA040518: AB_10794877" "unprognostic (2.99e-1)" "unprognostic (1.74e-1)" "unprognostic (2.63e-1)" "unprognostic (1.74e-3)" "unprognostic (2.20e-3)" "unprognostic (2.01e-1)" "unprognostic (4.96e-2)" "unprognostic (1.95e-1)" "unprognostic (3.15e-1)" "unprognostic (5.70e-3)" "unprognostic (1.22e-2)" "unprognostic (2.23e-1)" "unprognostic (1.03e-3)" "unprognostic (3.51e-1)" "unprognostic (2.39e-1)" "unprognostic (6.06e-2)" "unprognostic (2.10e-1)" 4.6 3.9 7.9 1.7 7.2 5.6 3.2 8.9 7.7 5.0 2.4 3.7 1.0 3.9 2.3 4.0 3.1 2.8 2.4 7.1 7.2 2.3 2.0 1.9 1.3 5.2 6.1 7.3 0.8 7.0 1.4 1.2 4.7 4.5 4.0 2.5 18.6 3.6 1.0 11.0 1.3 3.8 3.8 5.9 1.4 1.2 9.4 2.2 1.5 2.0 1.5 2.0 2.7 4.7 2.9 1.6 1.3 0.0 0.0 0.3 0.0 0.3 0.0 0.6 0.4 0.0 0.5 0.0 0.3 0.1 0.0 0.5 5.1 1.4 0.1 0.0 9.7 0.2 3.1 0.0 0.3 24.2 0.0 0.5 3.6 0.0 0.0 3.9 0.2 4.7 0.0 15.2 0.3 0.0 2.4 2.7 1.0 0.3 2.7 19.5 0.0 17.3 5.6 2.6 6.3 2.3 4.9 0.0 0.1 0.1 7.7 1.9 0.0 0.0 1.3 3.3 2.2 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 11.3 0.4 0.0 0.3 0.3 0.1 0.0 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 7.9 7.2 8.9 7.7 7.1 7.2 5.2 6.1 4.7 3.8 9.4 4.7 17.0 0.0 0.0 2.3 1.5 2.5 0.5 1.9 3.4 3.3 1.2 0.8 3.9 0.0 3.5 0.0 2.1 0.0 0.1 1.8 0.0 0.8 0.0 0.5 2.6 10.8 3.6 0.0 18.5 0.6 0.0 2.3 0.0 0.3 0.0 0.2 4.2 2.1 0.1 3.3 21.1 0.3 4.1 0.3 0.6 0.0 1.2 0.1 1.8 45.0 0.0 1.9 0.0 13.6 1.8 0.8 1.0 3.0 8.4 0.9 0.0 0.3 1.6 1.6 0.0 0.5 1.4 0.2 0.2 6.8 4.7 0.3 1.4 8.4 1.3 0.3 SLC27A3 "ACSVL3, FATP3, MGC4365" ENSG00000143554 "Solute carrier family 27 member 3" Q5K4L6 1 153774354-153780157 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 106.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 7.4;granulocytes: 12.6;monocytes: 11.1" "Cell line enhanced" "Detected in many" "ASC diff: 53.3;MCF7: 30.8" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA006935, HPA067508" Enhanced Enhanced "Endoplasmic reticulum" Yes No "Cluster 52: Eosinophils - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "HPA006935: AB_1080003, HPA067508: AB_2685857" "unprognostic (1.88e-1)" "unprognostic (2.66e-2)" "unprognostic (1.34e-1)" "unprognostic (3.57e-2)" "unprognostic (2.70e-2)" "unprognostic (4.85e-2)" "unprognostic (6.08e-2)" "unprognostic (3.18e-2)" "unprognostic (4.22e-2)" "unprognostic (3.39e-2)" "prognostic favorable (5.23e-4)" "unprognostic (4.67e-2)" "prognostic unfavorable (6.33e-4)" "unprognostic (1.95e-1)" "unprognostic (4.41e-1)" "unprognostic (2.59e-1)" "unprognostic (2.08e-1)" 18.9 5.0 4.1 3.3 4.1 2.5 17.7 3.3 5.7 8.3 4.6 8.8 2.4 6.3 37.7 6.1 9.8 5.7 8.3 4.0 4.1 11.1 20.4 19.0 4.7 4.2 5.6 9.2 8.0 9.2 9.9 6.4 3.9 7.1 5.0 0.6 5.1 8.0 3.1 12.3 7.7 5.8 3.6 8.6 19.3 12.2 3.9 2.3 9.4 3.7 2.8 7.4 9.5 4.0 2.6 0.5 3.1 1.5 53.3 10.8 0.8 0.5 3.9 1.2 1.0 1.8 1.8 1.1 1.6 2.4 0.6 9.3 3.0 1.5 0.7 0.4 1.4 1.5 2.8 1.9 6.7 1.4 5.8 5.5 6.6 0.3 1.4 1.1 7.0 0.3 0.8 1.4 0.3 30.8 0.3 8.1 3.4 12.2 1.4 8.6 0.6 0.9 1.5 0.9 2.7 1.7 0.6 9.6 3.0 4.1 3.9 5.5 0.0 1.5 2.8 3.3 0.1 2.4 2.4 0.3 2.5 5.7 1.2 9.5 10.7 12.6 2.1 8.8 1.3 0.6 0.6 2.1 7.4 0.7 0.2 0.6 0.9 2.5 11.1 1.0 0.2 3.4 4.1 4.1 3.3 5.7 4.0 4.1 4.2 5.6 3.9 3.6 3.9 4.0 47.3 19.2 51.8 6.5 5.5 11.7 12.6 9.0 8.0 0.9 4.4 11.3 4.6 34.3 10.1 3.7 0.0 27.2 20.7 4.2 0.0 4.3 0.6 5.1 12.1 42.4 4.2 0.4 2.6 7.3 13.0 20.3 16.8 7.9 25.4 1.8 106.1 30.6 33.2 1.7 2.6 23.7 6.1 31.7 39.8 3.2 19.0 21.3 23.2 1.9 44.6 2.0 35.0 0.5 1.6 3.1 42.3 14.3 7.9 3.4 2.5 3.6 6.6 1.0 6.6 3.4 15.7 1.7 2.9 5.5 7.7 8.8 13.0 5.2 10.7 7.0 SLC39A7 "D6S2244E, H2-KE4, HKE4, KE4, RING5, ZIP7" ENSG00000112473 "Solute carrier family 39 member 7" Q92504 6 33200445-33204439 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 168.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053999 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" "Endoplasmic reticulum" "HPA053999: AB_2682338" "unprognostic (3.63e-2)" "unprognostic (1.23e-1)" "unprognostic (1.21e-1)" "unprognostic (3.24e-2)" "unprognostic (8.95e-2)" "unprognostic (2.51e-1)" "prognostic unfavorable (3.62e-4)" "unprognostic (4.87e-2)" "unprognostic (9.92e-2)" "unprognostic (7.20e-3)" "unprognostic (3.29e-1)" "unprognostic (2.40e-1)" "unprognostic (1.99e-2)" "unprognostic (4.80e-1)" "unprognostic (1.50e-1)" "unprognostic (8.22e-3)" "unprognostic (1.12e-2)" 52.5 73.7 2.2 3.6 2.4 2.4 51.1 2.5 2.7 51.0 5.4 66.7 7.2 60.8 8.6 47.1 44.4 5.8 63.2 2.0 2.8 45.1 75.0 64.9 3.0 3.1 2.6 40.9 98.7 12.8 74.1 8.2 3.2 55.8 8.7 1.9 90.9 7.5 31.5 38.4 58.5 8.3 2.5 47.7 71.4 29.0 3.2 2.8 67.2 2.8 4.4 42.4 41.2 2.9 10.7 9.6 8.6 8.2 25.8 15.9 13.2 17.8 25.3 23.1 23.1 16.7 6.6 5.1 11.9 22.9 12.4 7.5 8.3 14.5 9.7 16.6 10.1 9.4 10.0 25.1 18.2 10.0 30.7 16.0 13.6 15.1 20.6 13.5 11.7 8.3 15.5 7.7 10.2 9.8 4.3 7.4 8.1 23.2 9.9 5.7 6.8 12.2 14.0 5.8 6.8 5.1 8.6 37.2 13.2 5.4 25.0 10.3 10.9 13.1 17.4 8.2 9.8 18.3 15.1 3.9 7.5 8.7 15.0 2.2 1.8 2.0 3.3 1.1 4.4 1.2 2.0 1.2 0.7 1.2 1.8 1.7 0.8 2.1 1.0 1.3 1.0 1.5 2.2 2.4 2.5 2.7 2.0 2.8 3.1 2.6 3.2 2.5 3.2 2.9 40.0 25.6 34.8 7.2 23.4 36.1 29.4 53.6 19.4 27.4 36.7 18.5 33.1 34.3 54.7 25.8 29.2 103.0 22.9 75.5 5.9 73.8 0.8 26.9 47.3 40.9 25.3 28.4 4.3 86.1 129.1 64.4 66.8 53.7 20.8 29.5 28.2 34.4 42.9 11.8 5.9 135.1 48.8 14.8 35.3 2.7 46.0 22.1 40.9 5.6 23.7 42.9 24.7 8.5 8.3 67.8 54.9 42.9 91.6 60.2 56.0 25.9 28.3 26.8 19.7 35.4 43.0 9.4 11.5 26.0 40.9 168.7 23.1 69.2 61.7 51.3 SLC39A9 FLJ11274 ENSG00000029364 "Solute carrier family 39 member 9" Q9NUM3 14 69398015-69462390 "Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007921, HPA075390" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 6: T47d - Mammary gland" "Cluster 27: Mucus-secreting cells - Mucin production" "Endoplasmic reticulum" "HPA007921: AB_1080007, HPA075390: AB_2686748" "unprognostic (2.37e-1)" "unprognostic (9.29e-2)" "unprognostic (1.57e-1)" "unprognostic (2.53e-1)" "unprognostic (4.35e-2)" "unprognostic (1.10e-1)" "unprognostic (5.50e-2)" "unprognostic (1.71e-1)" "unprognostic (2.49e-1)" "unprognostic (2.75e-1)" "unprognostic (1.57e-1)" "unprognostic (1.92e-1)" "prognostic favorable (1.05e-6)" "unprognostic (1.20e-1)" "unprognostic (1.83e-1)" "unprognostic (1.09e-2)" "unprognostic (2.16e-2)" 15.2 21.6 17.3 12.1 17.5 10.7 24.4 17.7 24.6 18.2 20.9 20.3 21.5 14.8 25.6 23.1 15.6 14.3 12.2 17.4 18.9 29.8 43.0 15.6 12.7 17.0 17.3 13.7 28.5 26.4 22.8 17.7 17.0 19.0 21.5 12.7 33.8 15.1 7.9 18.3 19.4 15.5 18.7 16.0 21.8 8.9 18.3 18.0 22.2 11.6 17.8 15.3 15.3 20.1 55.0 46.3 26.9 28.7 46.2 34.6 25.1 31.9 40.2 30.7 34.8 35.4 49.7 49.3 23.8 39.8 14.2 45.3 30.9 30.5 37.4 31.9 17.0 28.9 23.0 24.8 36.0 20.9 38.1 30.3 50.3 27.1 40.5 30.6 30.8 38.1 22.2 44.2 32.5 33.6 33.0 26.1 20.9 47.7 31.2 32.8 37.6 30.3 40.9 56.1 28.3 46.1 32.2 55.1 22.2 20.2 76.9 37.8 30.4 50.8 36.2 22.1 24.6 48.8 27.4 36.6 47.1 25.4 42.0 11.2 10.3 9.4 7.9 9.7 8.1 6.9 6.8 7.7 11.3 4.8 6.7 7.0 8.7 6.8 9.4 5.9 5.5 6.8 17.3 17.5 17.7 24.6 17.4 18.9 17.0 17.3 17.0 18.7 18.3 20.1 13.3 19.2 12.6 37.9 13.4 12.1 8.0 19.2 17.1 8.4 27.7 14.1 7.9 18.6 18.0 16.5 6.2 14.1 7.3 42.8 5.9 15.0 16.2 16.0 16.1 17.0 29.4 15.4 31.0 25.1 17.3 14.3 22.4 17.8 12.0 13.8 22.1 67.7 15.9 10.1 30.9 30.3 14.2 24.5 8.7 22.4 13.1 13.8 7.2 24.4 16.4 9.5 12.3 30.2 37.0 28.6 22.4 12.8 18.6 18.7 34.6 15.8 24.6 11.2 6.6 12.6 12.0 13.9 9.2 18.3 12.5 17.8 9.2 14.2 25.7 20.2 SLMAP "KIAA1601, SLAP" ENSG00000163681 "Sarcolemma associated protein" Q14BN4 3 57755450-57930003 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 295.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002357, HPA002358" Enhanced Approved "Endoplasmic reticulum" NA NA 9200 "Cluster 49: Eosinophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" "Endoplasmic reticulum" "HPA002357: AB_1080023, HPA002358: AB_1080021" "unprognostic (3.70e-1)" "unprognostic (2.87e-2)" "unprognostic (1.82e-3)" "unprognostic (3.43e-2)" "unprognostic (3.34e-1)" "unprognostic (6.18e-2)" "unprognostic (1.47e-2)" "prognostic unfavorable (7.98e-4)" "unprognostic (1.23e-1)" "unprognostic (1.59e-1)" "unprognostic (2.59e-3)" "unprognostic (1.06e-1)" "prognostic favorable (1.58e-6)" "unprognostic (8.18e-2)" "unprognostic (1.93e-1)" "unprognostic (1.92e-2)" "unprognostic (6.08e-2)" 25.9 28.1 8.3 35.2 14.7 15.5 21.9 13.4 9.2 25.6 11.3 126.5 34.0 93.5 14.2 116.8 48.6 31.6 134.7 7.5 7.3 24.9 16.4 17.6 16.4 7.8 7.4 37.5 16.1 36.6 11.5 23.5 8.3 65.6 38.2 20.4 20.1 100.3 64.0 21.5 37.7 137.6 6.5 14.9 52.3 31.8 9.2 19.8 28.7 42.0 18.3 87.5 29.0 8.7 43.3 23.1 23.0 25.7 31.8 28.9 24.2 40.8 41.9 27.0 25.5 59.4 54.6 25.1 17.9 30.4 48.4 23.5 38.5 54.5 36.8 32.2 20.6 49.9 31.1 47.6 29.1 47.8 26.5 20.0 39.1 33.6 60.8 38.1 31.8 25.0 39.7 23.7 28.5 11.7 28.0 20.4 29.7 29.3 38.7 12.4 21.0 28.0 47.7 44.3 10.0 12.8 49.9 37.4 23.7 26.7 19.9 27.4 38.1 33.0 23.1 28.2 52.8 28.9 57.1 36.7 25.5 45.4 27.9 3.3 3.8 10.9 3.6 2.7 3.2 3.7 2.8 3.2 3.2 2.5 3.2 3.4 9.5 5.2 2.4 1.4 4.1 3.6 8.3 14.7 13.4 9.2 7.5 7.3 7.8 7.4 8.3 6.5 9.2 8.7 17.3 38.5 39.6 90.1 25.6 92.0 45.4 49.3 54.1 28.0 25.0 23.7 295.9 40.0 40.0 33.1 50.1 19.0 34.4 53.9 19.6 45.8 40.2 45.9 24.6 22.8 14.4 28.6 113.3 34.3 12.2 28.6 41.3 72.4 3.8 34.8 18.2 22.7 15.6 32.0 121.5 26.8 20.3 20.3 25.9 26.2 32.6 27.8 28.4 76.8 25.1 86.8 34.0 101.0 97.7 64.1 36.6 71.8 39.0 93.3 36.4 24.8 46.5 32.4 52.6 26.8 82.2 87.4 47.0 54.5 73.3 16.3 26.1 52.0 28.7 126.9 SMPD3 NSMASE2 ENSG00000103056 "Sphingomyelin phosphodiesterase 3" Q9NY59 16 68358327-68448508 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Lipid metabolism, Sphingolipid metabolism" "Developmental protein, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 61.5;lymphoid tissue: 52.0" "Cell type enhanced" "Detected in many" "dendritic cells: 77.1;Gastric mucus-secreting cells: 70.8;Horizontal cells: 301.2;Proximal enterocytes: 115.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "amygdala: 8.0;basal ganglia: 29.7;cerebral cortex: 24.9;hippocampal formation: 25.4" "Immune cell enriched" "Detected in many" 7 "plasmacytoid DC: 138.9" "Lineage enriched" "Detected in many" 7 "dendritic cells: 138.9" "Cell line enhanced" "Detected in some" "HMC-1: 9.7;MOLT-4: 14.7;RPMI-8226: 12.4;SCLC-21H: 13.4" "Region enhanced" "Detected in all" "basal ganglia: 115.2" "Region enhanced" "Detected in all" "basal ganglia: 67.7" "CAB033885, HPA065535, HPA069383" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" "Endoplasmic reticulum" "CAB033885: AB_1126788, HPA065535: , HPA069383: " "unprognostic (1.21e-1)" "prognostic favorable (7.72e-4)" "unprognostic (5.61e-3)" "prognostic favorable (3.86e-4)" "unprognostic (2.46e-1)" "unprognostic (5.85e-4)" "unprognostic (7.87e-2)" "unprognostic (8.12e-3)" "unprognostic (2.77e-2)" "unprognostic (1.30e-1)" "unprognostic (1.75e-1)" "unprognostic (1.81e-1)" "unprognostic (1.04e-3)" "unprognostic (5.02e-3)" "unprognostic (2.49e-1)" "unprognostic (1.19e-1)" "unprognostic (1.93e-3)" 6.8 2.1 8.0 3.6 29.7 1.8 2.8 1.8 24.9 2.7 0.1 13.8 61.5 1.4 0.1 2.1 3.8 9.0 1.5 25.4 0.5 4.0 7.4 2.5 4.2 0.0 0.2 4.8 2.6 0.1 16.5 0.2 0.6 4.6 6.9 6.5 3.0 0.3 2.4 13.6 57.7 0.7 0.5 3.4 23.2 8.6 5.1 52.0 2.7 0.0 1.9 1.7 2.5 2.3 0.3 0.8 0.4 0.1 0.0 0.0 5.5 0.4 0.0 0.4 0.1 3.1 1.0 0.4 0.6 0.3 0.2 1.2 0.0 0.0 0.1 0.3 0.7 0.1 2.7 0.3 0.0 0.0 9.7 0.0 0.0 0.0 0.2 0.5 0.0 0.9 0.9 0.3 0.3 0.2 14.7 2.8 0.6 4.9 0.1 0.7 0.2 12.4 0.0 0.1 13.4 2.7 0.4 1.6 0.7 0.2 1.1 0.9 0.0 0.4 0.8 1.4 0.1 2.3 1.2 0.3 0.2 0.9 0.2 4.4 0.0 20.7 2.3 0.1 0.3 1.7 0.2 0.6 0.1 0.9 0.6 0.3 0.1 0.1 0.0 138.9 1.9 1.2 8.0 29.7 1.8 24.9 25.4 0.5 0.0 0.2 0.6 0.5 5.1 2.3 0.3 3.2 1.1 1.0 2.6 0.1 1.5 0.6 0.0 50.8 1.8 0.6 2.9 15.7 1.5 0.0 0.0 0.0 77.1 44.7 0.0 1.3 8.5 3.0 0.3 0.6 25.8 0.4 33.8 0.9 0.1 5.2 70.8 0.5 0.0 0.2 0.7 9.4 0.3 301.2 20.4 34.7 2.0 1.0 0.5 18.6 15.2 2.9 0.0 1.9 0.6 0.9 1.0 10.6 1.7 1.6 39.9 45.9 2.5 3.6 115.1 0.0 14.6 3.9 0.0 0.2 0.3 10.0 2.1 0.1 1.0 0.0 6.2 0.2 21.6 5.4 SOAT1 "ACAT, SOAT, STAT" ENSG00000057252 "Sterol O-acyltransferase 1" P35610 1 179293714-179358680 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Acyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "adrenal gland: 165.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009533, HPA047171" Enhanced Enhanced "Endoplasmic reticulum" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" "Endoplasmic reticulum" "CAB009533: AB_633499, HPA047171: AB_2679967" "unprognostic (3.29e-2)" "unprognostic (7.60e-2)" "unprognostic (1.11e-1)" "unprognostic (3.21e-2)" "unprognostic (2.83e-1)" "unprognostic (1.81e-3)" "unprognostic (7.81e-3)" "unprognostic (3.29e-1)" "unprognostic (9.00e-2)" "unprognostic (9.84e-2)" "unprognostic (1.06e-1)" "unprognostic (5.45e-3)" "unprognostic (7.02e-3)" "unprognostic (4.67e-3)" "unprognostic (9.64e-2)" "unprognostic (4.67e-2)" "unprognostic (1.82e-1)" 14.6 165.3 4.2 18.1 5.7 17.5 8.2 5.5 6.6 13.7 9.0 13.0 12.2 11.7 6.6 4.8 17.9 20.5 5.4 3.3 6.8 12.7 14.1 20.9 15.1 10.1 6.1 10.7 27.0 13.4 6.3 19.1 8.0 27.7 14.8 10.3 39.4 9.3 4.0 5.7 12.7 16.5 8.0 15.1 16.3 11.0 6.7 8.1 9.2 3.7 13.1 11.7 4.5 12.8 74.6 34.1 27.7 41.0 104.7 56.6 147.3 35.1 61.7 76.2 88.3 35.2 82.6 42.0 53.9 64.4 92.6 26.8 88.6 20.9 81.8 48.0 18.2 19.5 26.7 36.9 42.9 33.5 7.5 45.4 13.3 89.2 75.8 32.1 33.3 50.5 42.7 21.0 120.0 15.9 35.9 10.8 13.4 11.8 11.2 44.4 35.8 24.4 66.1 45.9 8.4 21.5 54.3 22.9 20.1 32.3 24.0 22.8 31.9 89.8 43.1 99.5 78.2 29.4 115.3 35.5 35.7 17.9 170.6 55.4 53.4 1.6 26.4 34.2 25.0 12.9 24.0 24.8 48.9 10.4 23.0 23.3 39.3 37.9 23.7 8.8 33.2 32.5 4.2 5.7 5.5 6.6 3.3 6.8 10.1 6.1 8.0 8.0 6.7 12.8 14.9 22.4 33.4 11.4 16.0 9.9 10.1 11.3 8.0 7.3 7.2 4.6 8.5 30.0 14.5 20.2 14.6 17.6 21.2 16.0 1.9 42.5 29.5 34.9 32.8 16.0 59.9 9.0 12.1 25.0 51.6 21.3 18.3 34.5 14.0 9.2 15.4 24.2 70.3 6.7 15.0 25.5 22.4 77.4 41.9 14.5 32.6 74.9 23.2 29.0 55.4 7.6 19.6 10.6 7.3 20.3 13.3 25.9 17.7 26.7 8.7 14.9 46.2 14.5 26.3 9.2 13.5 6.8 9.7 5.0 5.3 8.8 24.8 44.3 15.5 8.5 SOCS2 "CIS2, Cish2, SOCS-2, SSI-2, SSI2, STATI2" ENSG00000120833 "Suppressor of cytokine signaling 2" O14508 12 93569814-93583487 "Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 203.6;Hepatic stellate cells: 134.6" "Cancer enhanced" "Detected in all" "prostate cancer: 16.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 177.8" "Lineage enriched" "Detected in many" 5 "granulocytes: 177.8" "Cell line enhanced" "Detected in many" "CACO-2: 192.0;K-562: 145.6;REH: 336.6;THP-1: 142.3" "Low region specificity" "Detected in all" CAB010356 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 14: REH - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "CAB010356: AB_2239660" "unprognostic (4.16e-2)" "unprognostic (2.09e-1)" "unprognostic (1.10e-1)" "unprognostic (1.87e-1)" "unprognostic (9.67e-2)" "unprognostic (1.64e-2)" "prognostic favorable (1.09e-6)" "unprognostic (1.07e-1)" "unprognostic (1.49e-1)" "unprognostic (5.35e-3)" "prognostic favorable (8.17e-7)" "unprognostic (1.71e-1)" "unprognostic (1.67e-3)" "unprognostic (2.35e-2)" "unprognostic (1.51e-1)" "unprognostic (7.40e-2)" "unprognostic (9.09e-2)" 71.5 34.8 7.8 10.4 12.0 11.5 68.0 7.2 8.5 92.6 23.1 40.5 11.7 91.8 42.0 16.5 42.4 20.7 28.6 9.8 9.2 42.8 59.1 61.9 9.2 8.1 10.9 19.2 13.8 64.5 55.3 36.5 8.8 81.4 17.0 4.8 9.5 45.4 9.5 9.4 17.3 89.5 6.6 8.5 30.8 8.7 10.4 21.4 32.8 6.1 9.1 32.1 50.4 7.8 3.5 4.9 16.8 15.2 9.1 16.6 19.8 20.8 77.0 15.2 6.6 192.0 7.8 1.0 0.7 19.3 4.1 39.8 88.6 5.9 17.3 69.0 2.5 13.9 1.2 2.7 13.8 4.2 28.5 28.3 4.9 16.7 22.7 1.6 2.1 8.7 145.6 3.1 2.4 1.8 0.8 6.8 47.4 3.2 7.4 336.6 0.3 3.6 4.1 7.4 28.8 34.2 7.3 11.5 57.5 16.0 0.2 142.3 2.3 47.2 0.7 0.3 11.7 2.0 1.1 1.4 0.9 12.0 28.8 177.8 0.2 7.7 25.4 0.5 34.2 0.4 31.2 23.3 0.2 4.3 30.6 18.4 1.1 26.8 0.4 2.0 19.8 14.4 7.8 12.0 7.2 8.5 9.8 9.2 8.1 10.9 8.8 6.6 10.4 7.8 203.6 9.6 78.7 1.0 1.4 18.0 46.0 3.2 1.2 8.2 30.5 16.9 6.5 0.0 24.3 22.0 4.2 36.3 15.5 20.8 62.6 13.7 9.8 10.5 94.9 100.5 8.3 33.2 10.9 37.4 6.7 34.6 7.1 20.2 24.1 9.9 134.6 11.6 14.2 69.0 12.3 13.3 4.1 8.9 20.7 20.3 91.6 6.0 17.8 8.4 108.4 1.5 18.6 1.0 1.3 8.8 21.2 101.2 6.4 95.2 20.0 27.5 5.4 1.2 78.9 15.8 32.9 9.9 10.5 1.8 10.5 35.0 15.7 12.7 15.7 30.1 SPTLC1 "hLCB1, HSAN1, HSN1, LCB1, SPTI" ENSG00000090054 "Serine palmitoyltransferase long chain base subunit 1" O15269 9 92000087-92115413 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Acyltransferase, Transferase" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 94.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010860, CAB018747, HPA063907" Supported Supported "Endoplasmic reticulum" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 1: Thyroid gland - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 7: Non-specific - Mitochondria" "Endoplasmic reticulum" "CAB018747: AB_2195864, HPA010860: AB_1080086, HPA063907: AB_2685148" "unprognostic (1.22e-1)" "unprognostic (1.75e-2)" "unprognostic (1.47e-1)" "unprognostic (3.51e-2)" "unprognostic (1.54e-1)" "unprognostic (1.23e-2)" "unprognostic (3.03e-2)" "unprognostic (4.22e-3)" "unprognostic (1.27e-1)" "unprognostic (4.06e-1)" "unprognostic (3.55e-3)" "unprognostic (8.37e-2)" "prognostic favorable (1.36e-6)" "unprognostic (1.13e-1)" "unprognostic (2.41e-2)" "unprognostic (4.28e-1)" "unprognostic (1.49e-1)" 35.6 32.6 24.0 27.3 27.0 23.3 44.1 26.0 34.2 43.1 28.6 42.3 34.7 40.4 41.3 54.3 36.7 34.1 21.5 24.3 26.6 42.8 23.4 33.6 25.7 27.8 27.5 43.8 26.5 48.0 17.3 42.4 28.0 32.9 44.1 19.8 31.3 28.1 14.2 41.3 37.9 31.4 27.9 26.3 37.1 26.5 25.6 25.9 53.0 18.6 34.4 37.2 34.7 31.6 73.0 48.8 46.8 41.6 120.0 92.0 78.4 74.7 94.2 65.3 66.3 31.5 150.7 38.6 45.1 93.9 78.3 198.4 49.7 68.1 73.0 39.8 36.1 36.7 32.7 51.7 80.5 65.5 49.9 82.6 92.6 68.0 74.8 72.3 62.5 43.5 83.8 46.6 91.1 69.6 34.7 47.6 67.5 97.4 57.9 39.4 58.7 33.3 84.1 37.9 35.0 37.2 104.4 81.1 61.3 62.4 39.2 54.2 72.3 58.8 48.0 73.9 56.8 33.2 44.4 23.9 74.2 39.3 79.4 32.4 33.1 20.2 16.7 36.1 17.0 15.4 18.0 17.4 30.6 15.5 21.4 16.6 33.3 18.5 34.2 18.4 25.7 25.5 24.0 27.0 26.0 34.2 24.3 26.6 27.8 27.5 28.0 27.9 25.6 31.6 40.7 38.5 38.3 27.7 22.1 10.6 13.6 14.5 26.2 6.9 33.2 20.6 4.1 4.3 25.9 36.8 14.6 12.7 24.4 8.0 9.8 53.4 94.8 34.7 42.5 23.1 2.4 7.2 35.3 56.4 15.6 32.3 13.7 47.4 24.6 26.9 6.1 4.3 11.0 6.7 32.5 7.2 12.2 5.7 10.3 26.1 6.2 24.6 12.4 20.6 22.0 13.7 7.2 36.7 52.1 60.8 7.1 6.0 26.2 9.8 11.7 28.5 28.0 8.7 13.1 12.1 23.5 35.3 25.9 27.6 9.1 21.8 21.9 33.2 6.9 14.5 SSR1 TRAPA ENSG00000124783 "Signal sequence receptor subunit 1" P43307 6 7268306-7347446 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011276, HPA017062" Enhanced Supported "Endoplasmic reticulum" NA NA 1600000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "HPA011276: AB_1857503, HPA017062: AB_1857505" "unprognostic (2.27e-1)" "unprognostic (2.10e-1)" "unprognostic (5.98e-3)" "unprognostic (1.57e-2)" "unprognostic (3.10e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (4.92e-4)" "unprognostic (7.83e-2)" "unprognostic (2.27e-2)" "unprognostic (4.72e-2)" "unprognostic (1.68e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (5.79e-6)" "unprognostic (3.17e-1)" "unprognostic (2.56e-2)" "unprognostic (6.51e-3)" "unprognostic (2.19e-2)" 64.0 64.4 20.3 89.6 24.6 101.9 70.3 25.4 24.8 88.5 35.7 65.3 65.6 62.7 74.2 71.6 50.8 64.5 41.2 19.0 28.9 58.6 95.5 56.7 68.4 27.6 25.2 67.0 67.9 49.4 25.8 71.5 27.2 59.2 76.4 36.6 79.7 56.0 28.3 42.6 62.4 76.9 23.7 62.4 68.2 38.5 27.8 55.9 84.8 29.1 84.2 74.4 32.8 34.7 122.2 121.7 92.3 171.7 244.9 173.1 144.4 274.5 225.5 183.4 219.1 167.5 98.5 162.9 472.1 282.5 168.3 107.0 112.0 156.6 251.6 172.2 94.6 174.3 130.6 350.7 253.4 325.6 189.6 154.2 169.0 210.2 429.2 140.4 205.2 80.4 199.3 191.1 204.6 146.4 89.6 86.6 78.2 136.5 137.2 120.1 116.0 615.7 161.3 171.5 124.6 57.9 167.0 91.1 263.4 276.8 147.9 141.7 183.1 196.1 149.0 153.3 238.1 195.7 312.1 130.4 95.3 180.4 367.1 146.1 169.5 114.5 82.9 121.9 105.6 73.0 91.7 93.9 199.9 56.1 86.3 86.9 93.3 85.7 110.1 139.3 109.4 214.7 20.3 24.6 25.4 24.8 19.0 28.9 27.6 25.2 27.2 23.7 27.8 34.7 54.0 28.9 48.1 32.3 106.1 77.8 62.1 120.2 69.4 75.4 85.3 46.1 48.5 84.4 93.7 130.6 100.1 78.2 118.6 65.4 15.6 96.0 16.1 48.7 96.0 69.6 62.3 80.8 38.6 103.0 208.5 95.4 68.8 74.3 47.5 64.0 78.1 148.1 130.0 70.7 41.3 130.4 81.4 157.3 251.5 12.4 78.6 129.7 94.3 35.6 131.5 64.1 87.6 49.8 47.8 71.9 47.0 73.0 302.1 111.2 61.5 67.1 57.8 104.2 26.3 57.6 71.6 53.4 58.7 96.0 75.4 121.8 83.6 61.2 93.6 70.4 SSR4 TRAPD ENSG00000180879 "Signal sequence receptor subunit 4" P51571 X 153793516-153798499 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Congenital disorder of glycosylation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 3119.7" "Cell type enhanced" "Detected in all" "Plasma cells: 6002.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045209 Enhanced Supported "Endoplasmic reticulum" NA NA 110000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "HPA045209: AB_10961407" "unprognostic (3.56e-2)" "unprognostic (1.32e-2)" "unprognostic (4.00e-3)" "prognostic favorable (1.76e-4)" "unprognostic (8.74e-2)" "unprognostic (5.57e-2)" "unprognostic (7.99e-2)" "unprognostic (4.58e-2)" "unprognostic (2.10e-1)" "unprognostic (5.04e-3)" "unprognostic (5.74e-3)" "unprognostic (8.76e-2)" "prognostic unfavorable (5.51e-6)" "unprognostic (8.18e-2)" "unprognostic (2.24e-1)" "unprognostic (6.01e-2)" "unprognostic (5.33e-2)" 213.5 311.6 152.0 232.1 153.6 498.9 252.7 157.1 186.5 319.0 195.6 366.6 341.6 192.4 885.6 233.5 201.7 185.2 295.2 148.9 190.3 203.4 397.6 236.5 319.0 161.8 156.3 182.8 3119.7 157.1 676.5 120.5 159.2 263.8 267.7 37.1 922.8 416.4 127.4 191.5 256.6 120.5 162.7 396.6 495.0 160.9 158.1 158.0 221.0 74.1 324.6 243.8 217.3 171.5 344.2 428.9 148.7 834.4 785.2 412.4 299.5 278.6 431.1 299.9 407.3 547.9 298.3 476.9 721.8 450.4 262.4 332.8 259.2 270.6 111.8 192.6 212.0 128.4 380.1 446.0 669.0 370.7 352.6 511.9 376.6 256.9 353.2 265.3 327.4 240.8 145.4 1027.1 239.8 616.8 222.3 578.1 90.8 941.3 685.7 247.3 178.4 922.7 394.2 413.9 285.8 228.8 159.3 301.7 333.1 161.9 188.8 821.6 263.9 174.4 189.9 324.4 377.5 1449.6 774.0 576.4 364.7 630.8 295.7 652.3 594.6 286.7 616.7 476.9 762.6 695.6 629.2 613.7 598.0 644.7 538.8 555.2 93.8 697.3 396.5 1751.9 515.9 1330.5 152.0 153.6 157.1 186.5 148.9 190.3 161.8 156.3 159.2 162.7 158.1 171.5 228.6 166.7 301.9 7.5 824.1 257.2 372.4 566.8 167.9 53.6 451.1 380.1 334.8 357.4 464.7 318.2 56.3 311.4 521.0 473.2 168.3 544.9 476.1 276.9 513.6 263.0 747.5 175.3 3.6 627.4 700.6 357.3 344.0 454.8 352.2 257.0 241.3 723.3 439.0 35.3 5.3 967.6 547.3 339.1 416.6 1753.1 336.7 344.5 1428.3 4.7 409.3 174.7 432.5 8.0 11.1 487.0 595.8 247.1 6002.3 633.3 581.0 414.8 340.6 83.4 118.3 174.3 300.7 199.4 207.9 306.1 322.2 564.6 473.4 600.1 548.8 490.0 ST8SIA6 SIAT8F ENSG00000148488 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6" P61647 10 17315421-17454595 "Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.5;lung: 5.9" "Cell type enriched" "Detected in some" 5 "Microglial cells: 137.7" "Cancer enhanced" "Detected in some" "breast cancer: 5.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 8 "HMC-1: 208.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA011635, HPA072708" Uncertain Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 3: HMC-1 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "HPA011635: AB_2194921, HPA072708: " "unprognostic (4.86e-3)" "unprognostic (7.01e-2)" "unprognostic (5.85e-3)" "unprognostic (2.21e-2)" "unprognostic (3.43e-2)" "unprognostic (2.21e-2)" "unprognostic (1.11e-2)" "unprognostic (6.81e-2)" "unprognostic (2.32e-1)" "unprognostic (3.23e-2)" "unprognostic (7.53e-2)" "unprognostic (1.25e-1)" "unprognostic (2.48e-2)" "unprognostic (3.26e-4)" "unprognostic (2.43e-1)" "unprognostic (2.22e-1)" "unprognostic (1.07e-3)" 0.7 0.3 5.8 0.4 4.1 1.8 5.2 3.2 3.6 0.3 2.4 0.6 0.3 0.4 4.6 0.5 0.3 0.5 3.4 2.9 3.3 0.8 1.0 5.9 0.2 5.4 10.5 0.4 0.2 0.0 0.3 1.1 4.6 1.5 0.4 0.4 0.6 0.2 0.2 1.0 0.4 0.3 3.6 0.6 0.3 0.3 8.0 0.3 0.4 0.8 0.4 0.2 0.4 4.3 0.2 0.2 0.1 1.7 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.6 0.6 0.0 0.1 0.3 0.3 0.5 0.1 0.0 0.0 0.4 0.2 25.9 0.4 0.5 0.0 0.0 208.0 0.1 0.0 0.2 0.1 1.8 0.0 0.3 4.6 0.4 2.5 1.9 1.1 0.4 2.1 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.0 9.3 0.2 1.1 0.0 3.6 0.1 0.3 0.0 0.1 0.1 0.2 0.1 0.1 0.4 0.1 1.7 0.5 0.5 0.5 0.1 0.2 0.1 0.3 0.3 0.2 0.3 0.3 0.4 1.0 0.7 0.3 0.2 0.8 0.2 5.8 4.1 3.2 3.6 2.9 3.3 5.4 10.5 4.6 3.6 8.0 4.3 0.6 0.0 0.0 2.6 0.1 0.6 0.1 0.2 0.0 0.0 10.0 3.9 0.8 0.0 0.2 0.0 0.0 0.0 5.5 1.2 0.0 0.0 0.5 0.1 0.0 10.9 0.0 25.5 3.0 0.0 0.0 0.3 0.0 0.8 10.2 2.8 26.7 0.0 0.1 0.0 4.4 0.0 0.0 0.9 0.0 0.6 0.0 0.2 8.8 137.7 0.2 0.0 8.2 1.5 1.1 0.1 0.1 0.0 1.8 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.8 0.3 0.0 0.0 0.0 2.4 0.1 0.0 0.1 STBD1 "FLJ41801, GENX-3414" ENSG00000118804 "Starch binding domain 1" O95210 4 76306733-76311130 "Plasma proteins, Predicted intracellular proteins, Transporters" "Autophagy, Carbohydrate metabolism, Glycogen metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 130.3;skeletal muscle: 248.5;tongue: 154.7" "Cell type enhanced" "Detected in some" "Distal enterocytes: 9.1;Ductal cells: 7.9;Glandular and luminal cells: 5.1;Plasma cells: 7.0;Proximal enterocytes: 19.5;Respiratory ciliated cells: 6.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 140.7;U-266/70: 62.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA011952, HPA012849" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 2: Karpas-707 - Immune response" "Cluster 45: Enterocytes - Digestion" "Endoplasmic reticulum" "HPA011952: AB_1847461, HPA012849: AB_1847460" "unprognostic (1.46e-1)" "unprognostic (1.02e-3)" "unprognostic (4.29e-2)" "unprognostic (1.95e-1)" "unprognostic (2.57e-1)" "unprognostic (4.72e-2)" "unprognostic (1.35e-2)" "unprognostic (6.84e-2)" "unprognostic (3.06e-1)" "unprognostic (1.03e-1)" "unprognostic (4.96e-3)" "unprognostic (4.42e-2)" "unprognostic (3.52e-2)" "unprognostic (2.93e-1)" "unprognostic (2.00e-1)" "unprognostic (2.84e-1)" "unprognostic (5.74e-2)" 109.7 5.3 4.3 7.3 4.0 19.9 11.8 3.5 6.3 7.0 2.9 29.0 9.6 9.3 3.2 15.1 13.7 12.8 52.7 4.0 7.0 10.0 130.3 14.1 1.3 6.7 5.4 10.0 12.0 7.9 1.7 16.8 6.2 20.7 26.4 4.0 4.7 13.9 248.5 1.5 26.1 28.0 5.6 2.2 15.5 9.7 5.6 1.3 2.6 154.7 2.1 22.1 4.5 5.6 15.9 9.9 2.0 10.0 46.3 13.9 12.7 21.9 21.6 12.0 12.6 12.6 17.9 0.0 13.1 25.8 26.2 9.2 9.6 6.1 7.4 52.4 3.6 1.7 18.2 16.5 4.8 9.5 10.5 7.1 24.0 10.2 8.2 32.4 0.9 0.0 0.6 140.7 23.7 13.0 0.6 7.4 2.5 24.1 7.2 0.0 3.8 9.9 8.0 17.2 2.6 17.7 12.9 20.2 0.3 5.0 4.9 3.7 3.9 11.6 5.9 29.4 12.5 62.8 17.1 0.0 19.6 7.5 5.4 0.1 2.6 5.7 2.0 3.1 1.1 0.1 2.4 2.4 2.5 0.0 0.5 0.9 0.3 4.4 1.2 0.3 0.8 1.3 4.3 4.0 3.5 6.3 4.0 7.0 6.7 5.4 6.2 5.6 5.6 5.6 0.0 0.0 0.5 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.6 0.2 9.1 0.0 7.9 0.0 2.8 1.5 0.1 0.0 0.4 0.0 3.9 1.4 1.0 2.6 5.1 0.0 0.3 0.0 1.5 0.2 0.0 0.0 3.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.6 0.0 1.0 0.0 0.0 3.3 2.9 0.0 7.0 0.5 19.5 0.3 6.6 0.0 0.0 1.1 3.0 0.2 0.0 1.1 0.0 0.8 0.3 0.3 1.4 0.9 STC2 STC-2 ENSG00000113739 "Stanniocalcin 2" O76061 5 173314723-173328447 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "breast: 143.6" "Cell type enhanced" "Detected in many" "Breast glandular cells: 278.3;Breast myoepithelial cells: 119.6;Extravillous trophoblasts: 59.5" "Cancer enriched" "Detected in all" 6 "breast cancer: 91.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "LHCN-M2: 1019.9;T-47d: 940.0;U-138 MG: 382.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" HPA045372 Approved Approved "Endoplasmic reticulum" "Secreted in other tissues" NA NA 19000000 "Cluster 5: Breast - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" "Endoplasmic reticulum" "HPA045372: AB_10961040" "prognostic favorable (7.40e-5)" "unprognostic (2.40e-2)" "unprognostic (9.03e-3)" "unprognostic (1.21e-1)" "unprognostic (1.89e-3)" "prognostic unfavorable (1.76e-6)" "prognostic unfavorable (3.07e-5)" "unprognostic (5.28e-3)" "unprognostic (6.12e-3)" "unprognostic (1.53e-1)" "unprognostic (2.13e-1)" "unprognostic (3.19e-1)" "prognostic unfavorable (4.17e-8)" "prognostic unfavorable (7.57e-4)" "unprognostic (8.56e-2)" "unprognostic (5.06e-2)" "unprognostic (7.93e-3)" 7.4 1.7 0.7 2.4 0.9 0.0 143.6 2.2 3.1 13.2 1.9 4.8 0.6 3.0 0.3 2.0 2.0 6.4 9.9 3.0 1.8 3.6 0.8 11.3 1.1 5.0 6.4 0.7 32.6 3.3 1.7 28.0 3.7 4.8 0.6 7.7 1.0 6.7 4.4 12.8 2.7 21.2 1.3 11.5 3.4 0.7 2.9 0.2 9.1 4.9 0.3 4.7 3.0 3.0 52.5 15.3 2.7 13.0 47.9 20.5 133.8 234.5 239.4 59.1 115.0 74.4 36.7 0.0 33.4 139.8 298.2 21.5 33.8 72.0 102.5 0.1 18.9 0.0 26.7 50.2 311.3 15.8 4.3 43.6 117.9 133.3 7.9 274.4 16.7 42.4 2.4 0.1 1019.9 41.6 0.7 0.7 7.9 23.4 73.2 0.3 36.5 27.4 0.0 3.9 35.6 9.6 10.3 1.1 42.5 10.4 940.0 15.9 151.5 382.8 1.3 229.1 49.2 42.0 24.3 10.5 74.6 0.1 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.9 2.2 3.1 3.0 1.8 5.0 6.4 3.7 1.3 2.9 3.0 6.9 0.0 0.0 0.0 0.4 5.0 0.2 4.9 0.6 11.1 278.3 119.6 27.1 0.0 0.6 0.0 0.0 37.0 2.4 0.4 0.0 31.6 0.6 9.5 1.0 25.3 7.2 0.0 0.2 13.1 59.5 16.7 0.0 16.1 0.0 0.0 3.6 0.0 5.2 0.0 0.2 0.2 0.0 0.0 4.8 1.0 23.0 0.5 10.6 1.0 0.0 0.9 0.0 0.0 0.1 7.8 0.0 0.4 0.0 0.8 0.0 4.5 0.2 2.4 0.0 2.3 24.6 0.7 0.8 0.5 6.3 21.9 1.0 0.9 0.4 0.5 STIM1 "D11S4896E, GOK" ENSG00000167323 "Stromal interaction molecule 1" Q13586 11 3854527-4093210 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 77.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011088, HPA012123, CAB037128, CAB037288" Enhanced Enhanced "Endoplasmic reticulum" NA NA 1900000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Endoplasmic reticulum" "CAB037128: AB_1079007, CAB037288: AB_1079008, HPA011088: AB_1849884, HPA012123: AB_1849882" "unprognostic (2.06e-1)" "unprognostic (9.75e-2)" "unprognostic (1.34e-1)" "unprognostic (3.85e-3)" "unprognostic (3.13e-2)" "unprognostic (4.12e-1)" "unprognostic (3.43e-1)" "unprognostic (1.59e-1)" "unprognostic (2.25e-1)" "unprognostic (7.41e-2)" "unprognostic (1.86e-1)" "unprognostic (2.88e-2)" "unprognostic (9.35e-2)" "unprognostic (1.40e-1)" "unprognostic (2.73e-1)" "unprognostic (3.48e-2)" "unprognostic (1.39e-2)" 40.6 18.4 32.9 22.3 31.5 46.4 33.1 18.1 34.5 40.4 30.5 33.7 18.1 39.3 18.2 65.6 39.0 25.1 24.0 30.5 23.1 20.0 38.0 26.8 29.8 17.4 22.9 41.2 30.1 43.7 18.0 17.5 18.9 26.0 24.6 11.4 61.1 24.3 111.9 47.1 31.3 34.3 18.6 31.5 32.2 25.4 26.9 68.6 40.9 49.7 29.7 32.2 40.4 22.4 42.4 48.5 14.1 23.5 60.9 55.4 22.2 31.1 31.0 22.6 28.5 24.3 13.8 44.7 35.4 46.2 50.9 74.3 20.1 21.5 19.3 36.7 30.5 70.1 19.2 36.0 53.0 58.9 40.1 56.8 53.2 32.0 90.7 28.2 31.7 59.6 44.2 80.1 24.7 9.8 55.8 20.7 5.4 23.3 18.1 13.8 22.1 41.7 38.2 23.7 3.4 14.2 51.2 33.5 19.2 22.5 12.7 32.4 34.0 40.2 13.8 42.2 25.1 88.0 71.9 22.5 33.4 24.0 26.0 16.6 11.2 20.0 17.8 14.8 14.5 7.9 13.1 19.5 9.6 11.4 14.8 13.3 16.7 20.8 25.5 8.3 14.7 17.1 32.9 31.5 18.1 34.5 30.5 23.1 17.4 22.9 18.9 18.6 26.9 22.4 20.1 16.0 8.2 53.8 22.2 16.4 7.4 9.5 17.6 5.3 16.5 13.2 4.6 18.6 10.5 5.5 14.6 27.3 35.2 27.9 1.9 12.4 4.9 17.5 35.5 12.6 9.1 18.1 63.5 14.5 13.5 20.2 10.7 24.0 29.8 4.7 20.3 32.6 15.7 16.8 56.3 13.0 12.2 22.2 15.2 9.2 27.4 18.7 17.8 57.1 11.0 16.5 36.0 77.4 5.1 12.3 6.7 11.3 14.8 11.2 7.9 3.6 14.2 3.9 26.3 17.1 18.4 21.4 13.5 50.6 22.3 17.4 28.5 1.6 11.8 11.9 STT3B "FLJ90106, SIMP, STT3-B" ENSG00000163527 "STT3 oligosaccharyltransferase complex catalytic subunit B" Q8TCJ2 3 31532638-31637616 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 264.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036448, HPA036646" Approved Supported "Endoplasmic reticulum" NA NA 17000 "Cluster 15: NK-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" "Endoplasmic reticulum" "HPA036448: AB_2675129, HPA036646: AB_10673472" "unprognostic (2.17e-2)" "unprognostic (2.23e-1)" "prognostic favorable (7.91e-5)" "unprognostic (1.60e-1)" "unprognostic (3.11e-1)" "unprognostic (2.74e-2)" "unprognostic (2.02e-2)" "unprognostic (1.44e-1)" "unprognostic (1.04e-1)" "unprognostic (2.60e-1)" "unprognostic (3.26e-3)" "unprognostic (3.68e-2)" "unprognostic (3.86e-2)" "unprognostic (9.18e-2)" "unprognostic (1.42e-1)" "unprognostic (6.71e-3)" "unprognostic (1.02e-1)" 42.8 59.9 21.1 52.2 29.5 63.7 57.1 23.3 27.0 62.1 30.9 59.7 47.9 51.8 90.3 44.8 45.3 60.2 49.4 22.6 30.7 49.6 74.8 49.3 59.9 24.3 23.1 105.5 45.7 76.6 24.8 60.3 23.9 56.3 61.4 38.6 49.9 51.3 62.1 44.7 49.1 57.7 25.4 44.2 55.1 94.3 26.1 71.8 80.7 57.8 58.8 56.6 32.1 27.6 77.9 128.0 115.4 121.7 142.0 142.3 249.7 142.3 124.9 104.2 119.9 117.7 164.5 134.0 67.8 130.0 85.8 63.9 108.1 123.5 135.9 377.1 70.2 115.0 120.7 126.4 109.4 252.0 131.1 109.8 129.7 148.8 186.7 160.7 107.1 168.3 62.8 209.6 144.0 44.4 246.8 154.8 92.9 129.6 70.7 252.3 62.6 196.0 122.0 110.7 48.7 59.4 141.3 207.2 84.5 98.3 93.4 132.8 209.3 139.8 88.6 139.7 127.3 129.0 166.4 111.4 126.9 170.0 117.6 2.1 3.3 6.2 3.1 3.9 5.0 2.4 5.6 4.4 2.9 2.7 5.3 4.3 1.2 6.1 2.9 5.5 3.0 2.0 21.1 29.5 23.3 27.0 22.6 30.7 24.3 23.1 23.9 25.4 26.1 27.6 32.1 86.6 57.7 34.6 69.6 68.1 58.4 34.1 74.6 51.0 57.2 29.5 71.1 54.3 76.0 44.1 68.8 67.3 65.3 41.8 13.7 34.1 162.8 25.0 65.9 42.0 45.1 50.9 61.5 45.3 100.5 49.6 45.3 43.5 31.1 43.6 37.9 68.2 54.8 45.4 59.4 57.5 36.7 58.0 76.0 264.9 36.4 71.5 51.6 53.4 49.1 34.2 56.7 60.3 73.3 36.5 50.0 32.7 144.2 74.1 50.5 31.5 42.2 37.4 26.3 39.0 53.3 90.9 55.2 65.0 61.8 95.4 78.3 68.4 66.1 69.4 TECR "GPSN2, MRT14, SC2, TER" ENSG00000099797 "Trans-2,3-enoyl-CoA reductase" Q9NZ01 19 14517085-14565980 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Sphingolipid metabolism" Oxidoreductase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1013.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029780, HPA056488" Supported Supported "Endoplasmic reticulum" NA NA 10000 "Cluster 20: T-cells - T-cell receptor" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" "Endoplasmic reticulum" "HPA029780: AB_10603348, HPA056488: AB_2683149" "unprognostic (9.73e-2)" "unprognostic (3.69e-3)" "unprognostic (1.55e-1)" "unprognostic (8.08e-3)" "unprognostic (1.20e-1)" "unprognostic (3.96e-2)" "unprognostic (3.68e-2)" "unprognostic (1.24e-1)" "unprognostic (1.36e-1)" "unprognostic (9.16e-2)" "unprognostic (1.29e-1)" "unprognostic (5.05e-2)" "unprognostic (3.65e-3)" "unprognostic (2.53e-3)" "unprognostic (2.34e-1)" "unprognostic (2.07e-2)" "prognostic unfavorable (2.60e-4)" 102.7 162.6 189.0 43.1 201.7 74.2 100.4 220.8 237.5 156.8 216.5 78.5 106.1 53.2 103.2 373.2 87.1 49.7 78.4 180.1 200.0 112.2 133.9 67.8 55.7 209.6 191.2 80.9 105.5 306.1 78.7 68.0 212.2 85.7 59.3 82.8 222.3 83.5 366.3 263.5 95.9 36.7 207.6 75.4 81.7 182.7 199.9 65.8 92.7 209.6 85.3 51.6 185.9 230.2 220.5 162.1 149.5 169.6 214.7 97.2 156.9 62.8 175.2 196.3 242.9 225.3 246.2 113.8 127.4 134.2 152.4 328.8 158.1 254.3 84.0 192.3 165.9 193.7 225.4 254.6 129.7 139.5 143.7 144.9 201.8 174.3 96.1 98.4 93.7 169.2 128.9 391.5 104.0 289.3 170.1 248.3 155.6 556.1 227.6 154.4 96.1 521.1 275.1 115.8 183.2 113.0 103.1 278.4 139.6 77.2 151.3 274.4 55.2 160.5 66.8 141.0 212.6 118.4 119.8 122.7 163.8 212.6 162.2 55.6 72.7 52.5 137.8 106.4 148.8 100.1 180.1 159.1 124.2 99.1 207.1 164.5 32.7 183.7 83.9 137.1 290.1 170.9 189.0 201.7 220.8 237.5 180.1 200.0 209.6 191.2 212.2 207.6 199.9 230.2 60.4 73.7 71.1 47.7 87.6 169.5 227.5 297.9 125.7 90.8 161.1 155.6 52.9 120.1 221.5 165.5 123.0 509.5 88.1 159.2 56.7 166.2 443.9 102.2 40.1 64.7 100.0 80.1 15.3 225.1 525.5 81.8 89.7 64.2 36.1 90.1 73.2 143.1 188.0 112.7 19.2 144.0 199.4 113.8 99.3 1013.1 72.7 77.8 163.7 18.7 61.6 577.9 103.0 12.5 46.5 104.8 128.2 60.2 206.1 110.2 343.2 202.9 213.1 177.5 65.7 68.4 286.7 215.0 134.2 255.3 239.7 486.2 117.7 116.0 216.2 196.5 TLR6 CD286 ENSG00000174130 "Toll like receptor 6" Q9Y2C9 4 38823715-38856817 "CD markers, Enzymes, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 13.8" "Cell type enhanced" "Detected in some" "B-cells: 13.6;Hofbauer cells: 7.2;Kupffer cells: 12.2;Langerhans cells: 6.6;Macrophages: 11.6;Microglial cells: 20.6;monocytes: 14.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 13.4" "Lineage enriched" "Detected in many" 5 "granulocytes: 13.4" "Cell line enhanced" "Detected in many" "CAPAN-2: 13.3;GAMG: 13.5;RPMI-8226: 10.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA062733 Approved "Endoplasmic reticulum" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 57: B-cells - Immune response" "Endoplasmic reticulum" "HPA062733: AB_2684853" "unprognostic (9.82e-2)" "unprognostic (4.76e-2)" "unprognostic (3.30e-2)" "unprognostic (3.05e-2)" "unprognostic (1.91e-1)" "unprognostic (1.87e-2)" "unprognostic (1.83e-1)" "unprognostic (4.45e-2)" "unprognostic (9.26e-2)" "unprognostic (1.30e-1)" "unprognostic (1.05e-2)" "unprognostic (2.69e-1)" "unprognostic (7.62e-7)" "unprognostic (4.89e-2)" "unprognostic (1.02e-2)" "unprognostic (7.78e-2)" "unprognostic (2.12e-2)" 1.6 1.6 1.2 10.3 1.1 6.6 1.4 1.4 1.1 1.0 1.4 1.6 1.6 1.0 0.5 1.4 1.2 3.5 0.6 1.1 1.9 0.5 2.0 2.6 10.8 2.6 1.9 1.3 0.4 0.5 0.4 2.6 3.0 0.9 2.1 0.1 2.0 0.5 0.3 0.7 4.4 2.0 2.7 9.7 2.2 0.3 2.8 2.0 0.6 1.3 13.8 3.2 0.8 4.4 1.6 6.1 0.2 0.1 0.3 6.8 0.0 1.7 7.3 0.7 2.4 0.0 13.3 7.5 2.8 0.3 13.5 0.7 0.1 1.3 1.1 0.0 0.5 3.4 7.3 0.2 0.4 3.9 5.5 2.9 1.4 2.9 1.6 0.2 1.5 1.1 3.9 2.3 3.3 0.0 0.0 6.7 0.2 0.0 1.0 3.7 3.2 10.8 0.4 0.1 0.0 0.1 0.2 0.0 1.0 0.3 0.3 2.0 2.1 2.3 7.8 0.9 2.7 0.1 0.0 6.1 5.3 4.4 1.7 0.0 2.6 0.8 0.2 2.5 0.0 1.7 0.1 0.1 1.8 1.0 0.2 0.1 13.4 0.3 1.3 1.2 0.3 0.7 1.2 1.1 1.4 1.1 1.1 1.9 2.6 1.9 3.0 2.7 2.8 4.4 0.6 0.0 0.0 0.3 13.6 0.6 1.2 0.3 0.0 0.6 1.2 0.8 1.2 0.0 0.2 0.0 0.0 0.0 2.2 0.2 0.0 0.5 0.0 0.5 0.7 1.1 0.0 0.4 0.2 0.2 0.2 0.9 0.0 1.2 2.5 0.3 0.4 0.2 7.2 0.0 0.9 0.1 0.0 12.2 6.6 0.0 0.6 11.6 0.0 20.6 14.0 0.2 1.0 0.5 0.3 0.3 0.1 0.7 3.7 0.9 0.2 0.0 1.3 0.8 0.0 0.9 0.5 0.2 0.0 0.2 0.9 0.3 1.7 1.4 0.1 0.8 TMCO1 "HP10122, TMCC4" ENSG00000143183 "Transmembrane and coiled-coil domains 1" Q9UM00 1 165724293-165827755 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Disease variant, Glaucoma, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054768, HPA078775" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Endoplasmic reticulum" "HPA054768: AB_2682597, HPA078775: " "unprognostic (1.22e-2)" "unprognostic (3.28e-3)" "unprognostic (2.36e-1)" "unprognostic (1.45e-1)" "unprognostic (2.97e-1)" "prognostic unfavorable (5.17e-7)" "prognostic unfavorable (3.21e-4)" "unprognostic (5.92e-2)" "unprognostic (4.16e-2)" "unprognostic (7.95e-3)" "unprognostic (1.78e-1)" "unprognostic (5.20e-2)" "prognostic unfavorable (1.25e-4)" "unprognostic (2.85e-1)" "unprognostic (1.94e-1)" "unprognostic (2.14e-2)" "unprognostic (9.80e-2)" 67.5 92.5 46.4 51.6 50.2 48.4 91.1 53.8 63.5 74.0 72.2 127.0 115.7 55.9 111.5 58.5 65.9 80.1 56.4 46.4 55.6 110.3 162.5 55.0 62.4 54.1 55.5 59.5 73.5 143.6 33.8 57.4 55.0 79.6 128.7 74.3 77.8 69.9 48.7 39.3 108.9 61.4 56.6 46.5 80.7 75.4 49.8 89.3 103.8 48.0 70.8 97.7 29.1 60.6 158.4 172.1 132.2 77.9 243.9 120.7 126.9 259.4 191.7 156.0 162.1 249.9 229.2 99.1 267.4 195.9 67.1 214.7 171.8 140.3 175.1 252.0 164.2 121.1 180.3 158.7 195.1 216.6 154.1 159.0 173.9 179.5 142.6 148.4 117.1 122.6 329.7 186.0 227.3 123.1 172.1 160.6 169.4 527.6 197.3 125.0 143.4 256.1 204.7 198.4 133.5 235.4 201.3 209.2 170.9 195.0 277.1 275.7 121.5 138.9 116.5 123.8 248.3 357.4 521.1 346.5 111.4 139.7 187.4 213.3 172.2 172.9 159.7 169.4 170.4 151.8 168.7 173.1 135.5 132.6 134.3 156.5 132.1 156.6 201.7 243.8 207.1 290.3 46.4 50.2 53.8 63.5 46.4 55.6 54.1 55.5 55.0 56.6 49.8 60.6 124.0 96.1 70.7 23.8 95.6 84.8 89.8 264.5 75.1 79.1 142.9 135.9 62.6 224.4 181.1 213.3 68.8 136.1 138.9 371.5 43.0 202.3 82.2 131.4 147.9 92.7 88.6 75.5 20.7 191.7 148.4 113.1 64.2 154.7 76.5 71.9 106.7 326.0 140.9 75.7 24.9 137.0 227.9 106.4 76.0 151.6 123.6 92.7 99.6 16.9 78.9 236.7 152.4 25.6 23.3 227.0 215.7 129.4 153.5 73.6 290.0 151.5 175.2 75.9 124.9 67.7 101.7 232.1 87.7 89.4 92.9 111.4 109.2 117.6 143.6 94.5 TMCO4 DKFZp686C23231 ENSG00000162542 "Transmembrane and coiled-coil domains 4" Q5TGY1 1 19682240-19799945 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 42.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA014601, HPA014620" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Endoplasmic reticulum" "HPA014601: AB_2204302, HPA014620: AB_2669051" "unprognostic (3.31e-3)" "unprognostic (8.94e-2)" "unprognostic (9.71e-2)" "prognostic favorable (3.71e-4)" "unprognostic (6.99e-3)" "unprognostic (5.46e-2)" "prognostic unfavorable (1.12e-4)" "unprognostic (9.21e-2)" "unprognostic (2.60e-2)" "unprognostic (2.30e-1)" "unprognostic (1.84e-1)" "unprognostic (2.71e-2)" "prognostic favorable (4.12e-11)" "unprognostic (1.67e-1)" "unprognostic (2.22e-1)" "unprognostic (9.81e-2)" "prognostic favorable (3.64e-4)" 7.9 8.9 1.4 5.3 2.4 4.7 9.5 1.3 1.4 8.7 6.5 7.9 17.3 9.8 21.0 8.4 10.3 6.4 4.8 1.6 1.7 9.2 5.4 6.1 6.9 1.9 2.2 7.2 10.8 34.6 3.6 3.1 1.7 13.2 6.1 0.3 17.0 10.6 2.3 5.7 9.6 5.6 1.7 9.5 11.7 1.7 2.0 3.7 11.5 2.4 5.0 9.4 7.9 1.5 9.3 5.6 0.0 0.3 7.5 5.2 6.2 6.8 20.9 13.1 7.3 4.6 42.5 16.2 9.9 19.7 5.8 6.9 1.7 6.8 2.7 13.8 1.7 6.1 6.6 2.3 6.1 0.0 8.1 5.4 7.6 4.4 2.5 4.8 6.3 0.3 1.2 10.7 5.8 7.9 0.0 3.6 0.6 12.6 7.9 3.1 17.5 10.0 11.2 7.2 0.0 0.7 9.0 12.3 13.9 0.9 10.6 10.4 4.0 10.0 4.6 7.2 4.7 1.2 0.6 4.6 11.4 13.8 6.5 0.1 3.8 2.1 4.7 6.7 4.7 4.2 5.0 5.0 7.4 4.9 3.7 3.2 0.3 4.2 4.1 0.2 3.9 3.6 1.4 2.4 1.3 1.4 1.6 1.7 1.9 2.2 1.7 1.7 2.0 1.5 5.8 12.8 11.0 8.8 9.9 2.8 9.6 6.3 4.6 0.2 17.0 15.4 8.0 2.8 12.0 11.0 0.0 9.3 6.0 12.3 9.8 13.2 0.3 10.6 8.1 5.2 6.0 6.5 2.4 16.9 18.6 7.7 15.8 16.5 3.8 7.7 5.3 5.1 9.1 0.0 5.0 15.9 12.2 7.1 3.3 0.5 6.2 6.7 10.6 11.2 9.5 3.0 5.2 3.0 0.4 11.0 7.5 5.7 6.9 11.4 4.5 7.9 18.8 0.5 0.0 6.1 7.7 0.3 2.1 7.9 2.6 7.3 8.2 5.7 14.2 7.9 TMEM185A "CXorf13, FAM11A, FRAXF" ENSG00000269556 "Transmembrane protein 185A" Q8NFB2 X 149596556-149631912 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048295, HPA071744" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 51: Myeloid cells - Hemostasis" "Endoplasmic reticulum" "HPA048295: AB_2680345, HPA071744: AB_2686441" "unprognostic (9.76e-2)" "unprognostic (2.83e-2)" "unprognostic (7.73e-2)" "unprognostic (2.71e-3)" "unprognostic (4.08e-1)" "unprognostic (1.97e-1)" "unprognostic (4.34e-3)" "unprognostic (1.71e-1)" "unprognostic (1.83e-1)" "unprognostic (1.92e-1)" "unprognostic (2.78e-2)" "unprognostic (2.69e-1)" "unprognostic (3.17e-1)" "unprognostic (1.37e-2)" "unprognostic (1.90e-1)" "unprognostic (1.07e-1)" "unprognostic (1.40e-1)" 15.0 13.8 5.7 8.0 6.6 6.8 13.1 6.8 9.0 14.6 19.7 12.9 7.1 15.0 17.3 15.5 14.4 11.3 30.1 6.7 6.4 10.6 8.9 9.9 10.7 6.0 6.1 30.9 9.5 16.4 8.1 26.8 6.1 13.9 9.4 10.6 12.9 16.8 13.6 20.0 9.1 16.6 6.4 16.8 9.7 17.0 6.9 10.7 9.9 15.9 11.0 12.8 15.1 6.1 18.0 17.7 20.0 12.4 27.0 17.8 8.2 16.9 20.8 16.6 24.2 10.9 29.9 21.4 37.7 19.0 22.8 22.1 23.1 16.4 17.0 14.3 17.3 12.1 19.6 11.8 19.9 18.5 12.8 17.4 27.6 16.9 10.8 19.8 14.6 16.6 5.1 13.1 12.4 29.5 13.1 13.6 14.9 9.5 19.8 12.1 29.8 12.3 20.1 22.8 6.9 9.9 12.5 21.2 23.1 17.9 11.7 10.4 17.6 13.5 11.8 24.7 21.9 12.7 12.0 30.8 22.6 21.9 18.6 2.2 5.1 12.9 9.9 3.1 8.4 5.2 6.9 10.0 7.5 5.0 9.5 8.9 7.1 14.9 2.7 5.6 9.6 6.4 5.7 6.6 6.8 9.0 6.7 6.4 6.0 6.1 6.1 6.4 6.9 6.1 13.5 6.4 2.6 5.9 7.6 11.1 12.1 19.8 6.2 17.4 13.5 12.1 12.3 2.8 9.8 14.7 6.2 29.1 13.1 9.6 3.9 4.4 0.6 22.6 10.5 12.1 13.1 6.5 12.1 9.3 10.7 15.4 2.0 11.2 5.7 22.7 23.9 7.2 11.2 18.5 12.3 5.9 18.3 11.7 12.0 3.2 22.7 11.4 14.2 6.5 16.1 12.2 17.5 10.6 8.2 12.7 9.3 23.7 4.1 8.6 8.3 6.8 17.5 9.2 46.0 9.4 14.1 11.7 16.8 11.0 20.0 17.2 9.8 24.3 5.1 17.7 TMEM185B "FAM11B, FLJ20979" ENSG00000226479 "Transmembrane protein 185B" Q9H7F4 2 120217479-120223400 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 36.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048295, HPA071744" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Endoplasmic reticulum" "HPA048295: AB_2680345, HPA071744: AB_2686441" "unprognostic (1.23e-2)" "unprognostic (1.27e-1)" "prognostic unfavorable (5.44e-4)" "prognostic unfavorable (4.96e-6)" "unprognostic (1.35e-2)" "unprognostic (1.55e-2)" "prognostic unfavorable (5.71e-7)" "unprognostic (3.09e-3)" "unprognostic (1.65e-1)" "unprognostic (9.01e-2)" "unprognostic (1.96e-2)" "unprognostic (8.28e-2)" "unprognostic (6.03e-3)" "unprognostic (1.72e-1)" "unprognostic (1.61e-1)" "unprognostic (2.03e-1)" "unprognostic (1.04e-1)" 11.8 7.9 7.6 7.6 8.8 5.7 9.8 8.3 7.4 7.4 7.7 8.5 6.1 10.4 5.2 9.9 9.6 6.5 11.9 7.3 7.8 9.3 6.8 8.7 6.9 8.7 8.6 5.5 9.0 25.9 6.3 7.3 8.5 9.3 5.9 4.5 9.9 7.0 10.8 7.9 8.0 9.1 8.5 7.2 8.1 13.1 8.3 7.4 10.2 7.8 7.8 9.4 8.1 9.4 29.5 11.2 9.0 18.8 20.2 24.9 16.7 23.1 21.1 19.3 16.5 34.8 27.7 0.0 16.7 20.9 22.1 18.1 8.8 17.2 24.2 13.5 15.4 13.5 9.7 7.3 22.7 0.0 26.3 20.7 24.9 20.8 24.7 18.1 15.7 14.7 13.1 14.9 17.3 23.2 13.9 19.6 13.0 13.1 23.7 9.7 0.0 9.1 17.9 22.0 13.5 12.8 19.1 27.5 18.2 10.2 9.5 21.4 20.2 10.2 22.7 20.9 8.6 10.1 15.5 12.8 12.4 15.2 27.9 0.1 0.6 0.9 0.9 0.9 1.0 0.3 0.7 0.5 0.6 0.4 0.7 0.7 1.5 1.4 0.7 0.5 0.8 0.3 7.6 8.8 8.3 7.4 7.3 7.8 8.7 8.6 8.5 8.5 8.3 9.4 12.2 16.0 2.6 4.9 9.4 8.4 36.0 7.3 14.8 2.7 8.2 5.7 8.6 5.7 4.3 7.3 6.2 9.4 4.7 4.6 1.9 18.0 12.6 4.1 5.7 11.1 1.2 3.4 2.0 12.3 29.3 12.1 12.2 7.4 7.0 5.4 7.5 4.5 15.4 1.7 1.8 4.5 2.0 7.2 4.7 6.1 4.7 8.4 7.2 3.7 5.4 7.5 5.2 5.5 6.1 13.4 6.7 2.2 6.9 16.2 5.0 3.9 6.0 3.8 0.0 17.1 8.8 18.5 9.3 10.4 4.4 14.5 7.9 4.1 4.6 14.2 TMEM230 "C20orf30, HSPC274" ENSG00000089063 "Transmembrane protein 230" Q96A57 20 5068232-5113103 "Predicted membrane proteins, Transporters" "Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 502.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009078, HPA061421" Uncertain Enhanced "Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 39: Non-specific - Basic cellular processes" "Endoplasmic reticulum" "HPA009078: AB_1078345, HPA061421: AB_2684513" "unprognostic (1.39e-1)" "unprognostic (3.61e-1)" "unprognostic (3.73e-1)" "unprognostic (1.28e-1)" "unprognostic (3.71e-2)" "unprognostic (9.67e-3)" "unprognostic (5.85e-3)" "unprognostic (4.34e-3)" "unprognostic (4.18e-2)" "unprognostic (1.65e-1)" "unprognostic (2.74e-1)" "unprognostic (4.07e-2)" "unprognostic (9.70e-2)" "unprognostic (2.31e-1)" "unprognostic (2.09e-1)" "unprognostic (2.84e-2)" "unprognostic (1.55e-2)" 140.5 120.1 89.7 60.4 98.6 60.4 88.4 101.9 110.7 108.3 113.6 83.9 62.3 88.9 120.4 57.3 87.1 97.7 101.4 88.2 100.2 145.7 197.8 75.8 81.0 98.9 95.1 97.4 95.1 99.3 89.5 72.5 99.1 105.5 88.7 107.4 78.9 83.1 107.1 34.4 70.2 88.9 95.3 71.8 87.6 49.7 96.0 85.6 135.5 148.3 76.6 93.3 56.6 111.8 157.2 108.1 139.1 105.2 307.1 271.6 105.6 124.0 185.4 119.9 131.4 86.0 152.4 74.8 99.5 180.7 136.6 127.1 104.5 185.2 172.3 83.6 119.6 132.6 31.5 266.3 196.3 154.9 52.8 189.3 202.4 92.2 183.3 167.0 160.1 163.6 126.1 200.3 199.2 44.7 156.9 143.8 106.3 298.8 152.4 100.4 93.2 161.5 182.5 79.4 116.8 141.7 74.6 154.8 270.0 149.0 123.9 145.6 135.7 154.7 90.5 150.1 135.2 133.2 284.3 147.5 62.5 132.2 166.3 128.9 175.4 116.7 136.5 187.1 166.3 170.7 145.8 145.3 163.8 153.1 150.8 148.6 55.7 153.9 180.6 161.2 147.6 349.2 89.7 98.6 101.9 110.7 88.2 100.2 98.9 95.1 99.1 95.3 96.0 111.8 126.6 57.7 64.6 15.3 123.4 70.4 126.7 148.7 65.4 89.6 151.7 133.7 51.3 111.5 95.1 154.5 64.6 173.4 127.8 55.0 502.9 146.6 200.3 77.1 103.2 109.5 95.8 103.7 20.2 111.2 208.8 141.6 59.1 64.1 114.1 82.8 126.7 147.5 212.8 62.2 27.7 123.1 126.1 162.9 172.9 89.5 212.2 121.9 199.3 14.0 215.6 113.9 151.4 13.0 49.6 100.2 130.0 220.4 161.7 129.6 102.0 363.2 81.9 113.3 85.5 100.4 128.0 99.4 97.5 68.1 60.5 148.0 118.2 184.2 125.6 152.1 TMEM97 MAC30 ENSG00000109084 "Transmembrane protein 97" Q5BJF2 17 28319200-28328685 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 113.4;pancreas: 322.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 121.5;Exocrine glandular cells: 196.4;Granulosa cells: 212.9;Hepatocytes: 226.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CACO-2: 341.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044795, HPA076689" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 39: CACO-2 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" "Endoplasmic reticulum" "HPA044795: AB_10959306, HPA076689: " "unprognostic (1.35e-2)" "unprognostic (2.70e-1)" "unprognostic (1.39e-1)" "unprognostic (1.10e-3)" "unprognostic (1.81e-1)" "unprognostic (4.34e-2)" "unprognostic (3.20e-2)" "unprognostic (9.03e-2)" "unprognostic (1.04e-2)" "unprognostic (1.81e-1)" "unprognostic (1.11e-2)" "unprognostic (5.17e-2)" "prognostic unfavorable (1.24e-4)" "unprognostic (1.08e-1)" "unprognostic (2.26e-1)" "unprognostic (1.99e-1)" "unprognostic (4.01e-2)" 4.3 26.0 5.2 7.3 6.3 6.7 11.7 6.6 9.0 5.7 6.5 14.3 16.4 6.7 4.7 7.4 13.1 10.2 3.4 6.3 5.4 7.1 113.4 17.4 7.1 14.9 14.2 18.1 322.0 6.5 1.6 6.8 14.9 10.8 12.6 6.3 3.7 3.3 15.5 9.8 11.2 5.7 5.0 4.6 38.8 58.0 7.4 7.6 4.2 9.1 8.2 26.6 5.2 6.8 46.1 120.4 214.8 105.5 28.0 40.2 70.5 44.1 27.9 67.9 90.3 341.0 34.3 126.3 46.4 17.0 140.1 48.7 137.1 75.0 52.7 60.3 102.1 47.8 56.9 143.0 25.7 76.9 36.4 84.0 10.0 66.4 27.5 8.3 21.1 80.1 101.3 92.1 22.7 81.8 120.0 72.4 95.6 187.7 30.6 94.8 236.5 112.8 85.6 210.6 154.1 67.0 70.0 55.1 36.3 118.2 97.0 35.8 13.8 72.8 56.8 62.9 81.7 74.3 159.0 115.9 14.6 54.7 44.3 0.7 2.2 2.2 7.8 2.7 9.2 11.1 6.4 9.4 16.1 5.5 10.4 9.8 1.0 9.5 1.0 9.3 6.6 5.2 5.2 6.3 6.6 9.0 6.3 5.4 14.9 14.2 14.9 5.0 7.4 6.8 4.2 9.6 61.5 3.3 7.7 14.5 6.0 32.8 18.8 11.3 22.5 21.5 9.0 121.5 19.1 14.7 16.7 34.2 5.0 6.1 15.6 23.3 22.3 7.5 14.3 7.1 38.8 40.3 2.9 196.4 84.0 14.4 49.5 11.4 1.3 212.9 6.4 226.9 22.0 3.3 4.5 16.2 26.4 6.7 34.7 49.1 13.4 9.9 16.0 0.0 11.4 8.2 4.1 4.0 1.0 47.7 3.5 11.3 15.3 13.9 4.0 6.3 12.2 9.1 6.6 10.4 12.4 91.3 65.5 22.7 11.2 10.7 6.4 65.1 29.4 7.9 TOR1AIP2 "IFRG15, LULL1, NET9" ENSG00000169905 "Torsin 1A interacting protein 2" "Q8NFQ8, Q9H496" 1 179839967-179877803 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051849, HPA058348, HPA070542" Uncertain Enhanced "Endoplasmic reticulum" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 28: BEWO - Transcription regulation" "Cluster 2: Hepatocytes - Metabolism" "Endoplasmic reticulum" "HPA051849: AB_2681637, HPA058348: AB_2683687, HPA070542: AB_2686278" "unprognostic (1.22e-1)" "unprognostic (8.49e-3)" "unprognostic (2.61e-1)" "unprognostic (2.25e-2)" "unprognostic (2.15e-1)" "unprognostic (1.92e-2)" "unprognostic (4.35e-2)" "unprognostic (1.82e-1)" "unprognostic (6.17e-2)" "unprognostic (7.64e-3)" "unprognostic (3.06e-1)" "unprognostic (3.45e-1)" "prognostic unfavorable (2.29e-4)" "unprognostic (9.99e-2)" "unprognostic (1.05e-1)" "unprognostic (8.36e-2)" "unprognostic (1.36e-1)" 12.5 19.5 9.4 8.3 9.0 41.5 10.6 9.7 9.4 8.7 13.8 9.5 16.3 8.9 19.4 15.2 8.2 10.8 10.5 11.9 13.0 12.0 41.5 14.3 7.1 10.2 12.7 14.0 14.4 16.8 10.7 21.8 10.8 8.9 8.5 9.8 8.9 12.7 19.7 14.6 19.8 11.4 8.9 9.8 12.0 9.4 11.2 8.2 10.5 15.7 10.1 10.3 9.8 9.9 25.3 23.3 19.0 40.2 45.5 24.1 78.1 32.7 39.6 26.0 25.5 36.6 40.5 21.0 39.7 35.3 14.0 35.9 34.4 34.7 33.5 23.4 18.9 25.4 40.8 32.1 35.7 27.4 27.3 41.4 26.2 34.4 37.1 22.7 37.5 19.4 51.3 21.5 31.2 15.0 20.1 19.9 47.8 27.4 6.2 21.8 27.3 30.4 20.0 43.0 16.3 41.8 36.4 41.9 33.3 37.9 40.0 19.5 48.9 37.8 34.2 20.2 25.3 34.1 47.8 41.5 20.2 19.2 35.4 21.5 6.1 7.7 6.3 8.3 6.0 6.8 6.1 5.5 4.2 5.9 6.6 6.5 12.7 5.0 8.3 9.0 5.6 2.6 9.4 9.0 9.7 9.4 11.9 13.0 10.2 12.7 10.8 8.9 11.2 9.9 48.4 153.8 59.0 27.7 22.6 250.7 70.3 37.0 62.0 28.5 52.5 27.7 37.0 125.8 57.9 77.3 37.5 109.6 39.5 67.9 25.4 65.2 30.9 77.1 71.0 50.2 22.0 36.0 52.5 63.8 187.8 51.9 36.2 117.2 19.0 45.7 45.3 237.1 43.0 32.0 43.2 52.5 44.7 53.1 118.6 19.2 58.4 39.2 48.0 29.0 49.8 46.6 41.2 30.7 38.3 85.8 43.1 85.4 30.2 67.3 215.2 44.6 41.3 34.8 52.6 47.4 43.7 27.5 31.4 66.1 249.6 180.3 41.9 69.9 51.0 118.1 TRAPPC6B ENSG00000182400 "Trafficking protein particle complex 6B" Q86SZ2 14 39147811-39170532 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Neurogenesis "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047928 Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Endoplasmic reticulum" "HPA047928: AB_2680214" "unprognostic (3.89e-1)" "unprognostic (4.94e-3)" "unprognostic (1.80e-1)" "unprognostic (1.44e-1)" "unprognostic (7.60e-2)" "unprognostic (1.55e-2)" "unprognostic (3.79e-2)" "unprognostic (1.04e-2)" "unprognostic (3.09e-2)" "unprognostic (2.07e-2)" "unprognostic (4.57e-1)" "unprognostic (2.18e-2)" "prognostic favorable (1.76e-4)" "unprognostic (2.98e-2)" "unprognostic (3.41e-1)" "unprognostic (1.31e-1)" "unprognostic (1.90e-1)" 12.7 15.8 17.0 11.2 19.1 4.8 14.6 18.5 21.9 11.7 14.3 12.9 10.9 12.1 12.2 15.0 9.6 9.5 13.7 20.0 16.8 13.9 24.4 10.4 12.2 13.8 13.7 10.2 10.9 13.9 12.6 12.9 15.9 12.9 10.4 24.6 10.4 13.2 16.6 11.4 10.3 11.8 14.0 12.9 11.0 12.9 14.6 13.5 15.9 18.6 12.2 12.8 12.0 15.6 17.5 7.7 13.0 12.6 18.1 20.4 10.3 22.0 19.4 19.6 19.2 12.7 32.6 10.9 15.2 20.5 9.7 13.4 19.2 14.0 23.8 19.9 9.4 14.9 10.6 37.3 25.8 21.1 19.8 19.4 23.2 16.9 22.4 31.1 17.3 19.8 16.7 22.4 20.5 21.6 15.7 15.2 11.1 13.5 29.7 12.2 24.0 10.7 21.4 34.0 12.7 10.3 26.2 15.9 24.7 13.5 30.2 13.2 24.8 18.0 9.1 15.4 12.1 20.8 30.7 15.9 8.9 12.1 17.4 8.7 3.2 5.6 2.9 6.8 2.6 3.3 4.0 3.3 4.8 2.1 3.4 3.4 3.3 7.7 7.1 4.8 3.6 2.4 17.0 19.1 18.5 21.9 20.0 16.8 13.8 13.7 15.9 14.0 14.6 15.6 20.0 22.4 19.4 24.2 20.3 22.6 19.7 17.9 25.6 25.3 18.2 12.6 24.0 10.0 15.6 18.4 35.5 14.2 28.7 12.4 54.8 14.3 38.8 12.1 17.6 17.5 16.6 27.6 47.0 17.4 13.1 22.0 18.8 18.4 29.2 15.5 23.6 22.8 15.7 23.5 50.6 9.6 26.4 15.0 21.3 16.0 16.1 23.0 17.8 13.1 18.2 16.0 27.8 31.2 45.0 22.2 12.6 17.7 21.4 19.2 11.3 20.7 10.8 39.4 26.3 15.5 21.1 58.9 31.3 29.7 25.1 22.6 22.3 26.8 10.1 30.1 TTC39B "C9orf52, FLJ33868" ENSG00000155158 "Tetratricopeptide repeat domain 39B" Q5VTQ0 9 15163622-15307360 "Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 64.4;Paneth cells: 65.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 2.0;gdT-cell: 2.9;MAIT T-cell: 3.9;memory CD4 T-cell: 4.0;memory CD8 T-cell: 4.6;naive CD4 T-cell: 4.7;naive CD8 T-cell: 2.9;NK-cell: 6.3;T-reg: 3.8" "Group enriched" "Detected in many" 6 "granulocytes: 2.0;NK-cells: 6.3;T-cells: 4.7" "Cell line enhanced" "Detected in many" "HEL: 40.9;RT4: 23.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063162 Approved "Endoplasmic reticulum" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "HPA063162: AB_2684952" "unprognostic (1.64e-1)" "unprognostic (9.32e-3)" "unprognostic (1.47e-2)" "unprognostic (7.89e-2)" "unprognostic (7.47e-2)" "unprognostic (1.06e-1)" "unprognostic (4.12e-2)" "prognostic favorable (9.64e-6)" "unprognostic (5.99e-2)" "unprognostic (4.77e-2)" "unprognostic (1.59e-1)" "unprognostic (6.89e-2)" "prognostic favorable (4.08e-7)" "unprognostic (3.31e-3)" "unprognostic (2.12e-2)" "unprognostic (5.19e-2)" "unprognostic (1.48e-1)" 1.9 2.6 2.9 4.0 2.5 1.5 4.8 10.8 7.0 4.3 1.8 6.7 5.7 3.5 1.9 8.8 3.3 6.9 1.3 1.5 4.6 9.0 5.4 4.6 6.1 7.0 2.9 2.9 3.9 1.9 3.9 1.2 7.2 2.3 5.6 2.9 3.0 1.9 1.8 9.6 5.6 4.2 2.5 3.8 5.5 5.7 4.7 3.4 2.6 1.3 6.0 3.6 4.7 2.9 3.9 0.8 1.2 5.6 5.3 9.9 1.2 5.0 9.1 3.9 9.3 0.8 1.6 0.0 0.6 6.3 4.6 3.4 0.9 6.2 3.3 4.5 0.8 40.9 1.7 7.3 8.8 0.0 0.8 9.7 4.7 8.1 9.0 2.8 5.6 3.3 0.1 9.1 10.0 1.3 2.2 0.2 1.6 12.3 1.2 0.4 3.0 1.9 8.3 23.0 2.9 0.5 1.2 2.9 0.9 1.8 12.7 2.5 4.2 2.2 1.8 3.1 1.4 0.1 0.1 0.0 2.1 0.5 1.1 2.0 0.7 0.9 2.9 0.5 3.9 0.2 4.0 4.6 0.4 0.6 4.7 2.9 0.4 6.3 0.7 0.1 3.8 2.5 2.9 2.5 10.8 7.0 1.5 4.6 7.0 2.9 7.2 2.5 4.7 2.9 7.5 12.8 19.8 10.4 7.0 17.3 7.8 19.1 10.8 25.5 9.0 4.4 4.1 10.0 15.8 7.3 0.0 3.2 18.0 40.6 17.6 6.6 43.2 11.8 10.1 7.4 12.7 0.4 44.0 21.8 1.1 10.0 22.4 7.7 29.1 3.6 7.5 11.6 4.1 13.5 64.4 16.1 24.4 3.1 9.2 33.2 7.2 16.7 7.2 12.2 2.9 14.9 11.3 24.6 2.3 10.5 65.0 12.8 5.5 11.5 30.3 35.5 25.3 4.3 0.0 9.4 12.4 4.7 3.0 8.6 21.5 4.1 22.3 6.8 17.3 14.4 TXNDC5 "EndoPDI, ERp46, FLJ21353, FLJ90810, Hcc-2, MGC3178, PDIA15" ENSG00000239264 "Thioredoxin domain containing 5" Q8NBS9 6 7881517-7910788 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 42 "Plasma cells: 677.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 14 "memory B-cell: 13.0;naive B-cell: 6.9;plasmacytoid DC: 26.7" "Group enriched" "Detected in many" 21 "B-cells: 13.0;dendritic cells: 26.7" "Cell line enhanced" "Detected in all" "RPMI-8226: 2833.2;U-266/84: 6053.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034677, HPA034678" Enhanced Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA 6900000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "HPA034677: AB_2674275, HPA034678: AB_2674276" "unprognostic (3.15e-1)" "unprognostic (1.09e-2)" "unprognostic (4.27e-2)" "unprognostic (5.43e-2)" "unprognostic (6.95e-2)" "unprognostic (1.20e-2)" "unprognostic (6.07e-2)" "unprognostic (5.81e-2)" "unprognostic (3.56e-2)" "unprognostic (1.54e-1)" "unprognostic (1.18e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (1.16e-4)" "unprognostic (1.05e-1)" "unprognostic (7.98e-2)" "unprognostic (6.23e-2)" "unprognostic (1.08e-2)" 97.4 74.8 21.1 173.0 23.4 61.8 163.4 22.0 22.5 132.2 52.7 266.2 263.5 80.5 85.8 78.2 63.9 98.6 63.3 19.8 23.2 63.1 133.3 90.9 194.2 25.0 24.7 96.4 154.6 68.6 42.5 134.0 23.2 73.2 213.6 4.4 219.3 93.6 25.1 32.9 193.9 121.9 24.9 250.6 287.6 28.3 26.4 54.1 69.6 29.2 263.8 190.9 57.0 25.9 166.1 159.0 111.5 365.9 911.2 388.1 175.9 361.5 349.7 246.2 265.2 238.8 119.0 176.1 620.7 557.2 273.6 127.3 195.5 178.6 280.3 148.8 166.6 267.6 128.3 435.9 268.5 307.2 255.0 266.7 256.8 236.6 259.2 542.1 1334.0 109.7 170.5 1216.5 171.7 147.7 75.2 185.7 142.8 260.5 340.6 128.0 160.4 2833.2 201.1 149.6 168.7 90.5 462.4 280.2 209.4 514.9 143.5 133.9 369.7 280.5 194.2 243.0 386.5 1408.7 6053.9 305.0 144.7 191.7 392.2 0.0 0.4 0.0 0.9 0.7 0.7 13.0 0.2 0.7 1.0 6.9 0.2 0.4 0.0 0.0 0.1 26.7 0.9 0.5 21.1 23.4 22.0 22.5 19.8 23.2 25.0 24.7 23.2 24.9 26.4 25.9 1.3 0.0 4.8 0.0 14.6 0.9 0.2 0.4 3.4 0.0 1.8 1.3 0.2 0.0 2.0 0.0 0.0 0.9 5.6 1.2 0.0 9.0 0.1 1.1 6.9 3.2 4.9 11.2 0.0 10.7 1.9 4.1 6.1 2.3 1.3 0.6 3.9 4.9 1.5 0.0 0.0 15.9 0.0 0.8 0.7 0.0 0.0 1.3 3.6 0.0 1.8 0.1 0.0 0.0 0.0 9.5 1.5 0.4 677.7 0.4 3.2 0.5 1.7 0.5 6.6 0.5 4.2 0.1 0.1 3.9 0.1 1.2 2.0 0.2 5.8 0.2 UBXN4 "KIAA0242, UBXD2, UBXDC1" ENSG00000144224 "UBX domain protein 4" Q92575 2 135741734-135785056 "Predicted intracellular proteins, Predicted membrane proteins" "Unfolded protein response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 863.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036325 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "Endoplasmic reticulum" "HPA036325: AB_10669788" "unprognostic (1.22e-2)" "unprognostic (1.08e-1)" "unprognostic (5.24e-2)" "unprognostic (1.47e-1)" "unprognostic (1.54e-1)" "unprognostic (1.90e-1)" "unprognostic (1.17e-1)" "unprognostic (2.91e-1)" "unprognostic (5.40e-2)" "unprognostic (2.94e-2)" "unprognostic (2.63e-2)" "unprognostic (1.93e-1)" "unprognostic (1.83e-2)" "unprognostic (4.44e-2)" "unprognostic (1.27e-1)" "unprognostic (3.25e-2)" "unprognostic (5.14e-3)" 51.9 55.6 33.3 58.4 38.3 65.4 57.4 37.4 38.0 62.3 44.7 57.1 69.8 56.0 71.1 44.4 49.0 57.2 44.3 31.5 33.8 64.2 93.8 47.2 59.5 40.2 36.8 52.6 73.4 83.5 19.6 63.0 40.1 64.6 60.2 85.6 71.8 47.8 55.1 56.0 67.9 43.9 35.9 55.7 64.6 57.7 33.7 76.6 76.1 52.7 59.8 60.5 25.1 47.6 136.2 34.6 85.1 66.2 106.9 107.0 95.5 106.6 106.3 87.0 77.4 65.3 91.8 84.0 149.4 105.1 46.6 98.3 50.7 68.4 103.5 115.5 62.8 80.5 60.7 98.6 99.4 85.2 70.7 81.6 66.6 86.7 85.8 118.2 110.5 66.2 74.4 116.1 95.3 64.1 109.9 61.3 64.3 70.6 70.9 87.9 100.5 146.5 112.2 97.7 77.4 50.2 97.2 64.1 64.4 77.1 68.0 78.2 101.8 78.4 40.1 82.5 58.4 108.7 72.2 76.2 99.0 59.3 75.5 62.9 35.8 59.1 46.5 42.3 42.6 45.9 42.5 42.5 35.8 42.6 41.4 41.0 73.7 48.4 52.2 56.6 52.3 35.9 33.3 38.3 37.4 38.0 31.5 33.8 40.2 36.8 40.1 35.9 33.7 47.6 178.1 208.3 171.4 56.2 177.4 175.1 283.0 318.5 160.5 172.3 164.1 153.3 150.8 134.4 264.1 126.9 223.1 238.2 140.8 168.9 90.1 254.6 863.9 209.3 223.1 151.7 186.6 129.8 85.2 195.8 214.0 197.4 129.5 240.6 176.9 151.5 113.2 225.7 138.8 97.6 78.4 246.9 183.1 88.6 125.2 325.1 172.7 139.9 92.5 60.9 158.8 162.2 122.6 71.9 105.3 190.7 166.7 143.7 300.3 344.1 183.0 156.8 286.7 349.8 105.2 159.3 173.9 446.1 248.4 176.1 183.6 379.4 171.6 271.6 186.0 303.7 UCKL1 "FLJ20517, URKL1" ENSG00000198276 "Uridine-cytidine kinase 1 like 1" Q9NWZ5 20 63939829-63956416 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Host-virus interaction" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 148.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004722, HPA004769" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 72: Non-specific - Transcription" "Cluster 39: CACO-2 - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" "Endoplasmic reticulum" "HPA004722: AB_1080455, HPA004769: AB_1080453" "unprognostic (1.03e-1)" "unprognostic (2.77e-2)" "unprognostic (2.64e-1)" "unprognostic (8.34e-2)" "unprognostic (7.29e-2)" "unprognostic (1.20e-1)" "unprognostic (1.99e-2)" "unprognostic (1.87e-1)" "unprognostic (2.45e-1)" "unprognostic (1.29e-1)" "prognostic favorable (4.42e-4)" "unprognostic (5.87e-2)" "unprognostic (3.18e-2)" "unprognostic (9.11e-2)" "unprognostic (2.81e-1)" "unprognostic (3.01e-1)" "unprognostic (5.26e-3)" 41.9 47.3 21.2 17.4 23.2 24.7 44.0 32.0 33.2 53.7 24.4 46.9 33.5 41.9 7.2 50.4 49.8 11.9 57.1 20.4 21.2 55.1 55.6 40.6 21.2 23.9 21.5 74.9 46.3 17.2 52.3 17.9 23.7 49.4 8.7 55.9 43.4 17.6 61.1 43.0 51.8 9.6 19.4 64.7 37.2 25.7 22.7 15.9 59.0 36.6 11.0 40.1 54.0 31.4 29.2 30.3 25.5 34.2 18.4 15.6 40.9 22.8 15.4 46.2 23.0 72.8 22.0 29.3 37.5 14.9 31.6 46.7 20.0 31.4 9.2 12.3 33.6 22.2 67.8 108.1 20.3 38.2 40.8 21.9 27.6 18.5 15.1 18.3 21.5 28.4 32.1 30.3 14.6 37.4 45.1 66.3 18.9 23.0 70.0 45.4 19.2 51.0 19.1 41.4 60.3 35.3 32.9 31.8 36.2 12.7 33.4 34.1 24.2 48.7 18.2 32.1 30.1 31.5 18.1 13.6 25.0 27.1 18.8 8.0 11.4 9.9 18.3 19.7 21.0 31.0 17.8 15.8 13.3 17.1 10.1 12.4 1.8 8.5 22.2 7.6 20.8 12.1 21.2 23.2 32.0 33.2 20.4 21.2 23.9 21.5 23.7 19.4 22.7 31.4 31.7 25.6 8.3 17.0 24.1 18.9 21.4 29.9 14.8 30.7 13.5 17.3 20.3 18.6 17.7 9.2 83.4 31.2 16.8 24.7 23.5 19.4 2.4 18.2 17.0 19.4 21.5 5.5 7.8 11.1 23.6 17.5 25.0 22.7 13.3 21.1 13.6 12.4 17.6 20.2 9.7 21.2 32.6 11.4 16.4 3.7 17.7 14.5 10.6 4.7 17.0 18.5 12.3 10.1 12.2 17.5 27.4 20.7 21.4 17.8 38.7 16.1 11.3 148.0 26.3 16.2 30.1 12.7 12.4 22.5 19.0 33.4 22.0 28.4 24.3 19.2 UCN "UI, UROC" ENSG00000163794 Urocortin P55089 2 27307400-27308445 "Predicted secreted proteins" Hearing Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.2" "Cell type enhanced" "Detected in many" "Astrocytes: 7.8;Excitatory neurons: 6.5;Inhibitory neurons: 5.5;Oligodendrocytes: 6.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-266/70: 19.4" "Low region specificity" "Detected in many" CAB010911 Approved Approved "Endoplasmic reticulum" "Secreted to blood" NA NA 133000 "Cluster 40: NK-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "CAB010911: AB_261834" "unprognostic (7.35e-2)" "unprognostic (2.77e-1)" "prognostic unfavorable (8.10e-4)" "unprognostic (1.42e-2)" "unprognostic (5.08e-2)" "unprognostic (7.72e-2)" "unprognostic (5.69e-3)" "unprognostic (2.66e-1)" "unprognostic (2.48e-1)" "unprognostic (1.15e-1)" "unprognostic (3.80e-2)" "unprognostic (3.75e-2)" "prognostic unfavorable (1.84e-7)" "unprognostic (4.84e-2)" "unprognostic (3.87e-2)" "unprognostic (2.98e-1)" "unprognostic (1.11e-1)" 1.5 5.1 8.6 0.6 8.2 1.1 1.5 8.4 13.5 3.3 4.2 2.4 0.3 2.4 0.5 0.9 3.0 0.8 4.2 8.0 7.3 2.0 5.9 1.9 0.7 9.7 18.2 2.9 2.3 0.0 4.3 1.0 14.9 3.0 0.0 0.9 0.9 0.3 4.8 1.3 1.9 0.4 7.1 2.9 1.3 2.8 8.4 0.6 1.7 0.4 0.2 2.8 1.7 10.1 1.2 2.7 0.4 0.7 1.2 1.0 5.1 0.4 1.0 0.4 0.4 0.2 2.1 1.1 0.6 0.4 1.2 0.4 0.4 0.3 0.0 3.4 4.4 2.4 2.0 2.2 2.9 0.2 2.6 1.5 2.0 0.2 2.4 2.6 0.0 2.0 2.4 1.9 0.1 2.0 1.3 7.2 4.4 0.1 2.8 3.5 2.3 1.5 0.1 0.5 0.7 2.3 1.1 0.1 6.4 0.3 1.1 3.2 0.2 0.8 4.8 1.4 1.9 19.4 2.3 0.7 3.7 5.7 1.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.1 0.0 8.6 8.2 8.4 13.5 8.0 7.3 9.7 18.2 14.9 7.1 8.4 10.1 0.8 0.0 0.5 7.8 1.1 0.5 0.3 0.3 0.0 2.3 1.8 1.0 0.4 4.3 0.2 0.0 0.0 0.6 3.2 0.5 0.0 0.7 0.6 0.5 0.9 0.8 0.0 2.7 6.5 3.8 0.6 0.7 0.0 0.5 0.0 1.2 1.1 1.1 0.7 1.7 5.5 0.3 2.0 1.3 2.4 0.4 1.5 0.9 0.0 3.7 0.9 1.8 0.0 2.5 6.0 0.6 1.1 0.7 0.1 0.7 1.1 0.5 0.5 3.5 0.0 1.5 1.2 1.1 0.6 0.0 0.0 0.8 0.8 0.4 0.5 0.1 UFL1 "KIAA0776, Maxer, NLBP, RCAD" ENSG00000014123 "UFM1 specific ligase 1" O94874 6 96521595-96555276 "Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030558, HPA030559, HPA030560" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "HPA030558: AB_10600663, HPA030559: AB_10600537, HPA030560: AB_10602000" "unprognostic (5.40e-2)" "unprognostic (7.48e-3)" "unprognostic (1.06e-2)" "unprognostic (1.99e-1)" "unprognostic (8.12e-2)" "unprognostic (9.04e-2)" "unprognostic (9.99e-2)" "unprognostic (4.67e-2)" "unprognostic (1.89e-1)" "unprognostic (1.26e-2)" "unprognostic (1.49e-1)" "unprognostic (1.50e-1)" "unprognostic (4.46e-2)" "unprognostic (4.10e-2)" "unprognostic (5.92e-2)" "unprognostic (8.65e-2)" "unprognostic (4.46e-1)" 17.0 20.6 9.8 18.9 13.1 17.9 21.4 11.9 15.4 20.8 7.8 18.7 22.7 19.0 23.4 20.7 16.8 18.0 23.7 9.2 12.1 21.3 29.7 15.4 22.1 13.8 11.4 22.4 25.2 24.9 10.0 18.1 15.3 24.4 19.5 31.6 23.5 17.9 21.1 20.3 22.8 17.1 12.4 17.9 21.8 14.2 10.8 20.8 28.1 21.4 21.8 20.1 11.2 19.5 16.9 8.8 18.3 30.7 25.8 39.2 27.2 23.3 23.6 14.6 13.6 11.0 19.2 40.7 28.9 23.5 16.2 32.0 15.0 22.0 21.3 21.9 13.6 17.9 13.3 20.2 34.3 34.0 25.6 28.2 20.1 17.4 47.9 27.1 24.2 25.7 24.1 43.7 27.9 16.3 12.5 21.0 6.6 14.5 9.9 15.6 21.4 32.6 26.5 30.5 12.9 12.5 19.2 22.4 21.5 16.2 54.4 28.7 24.0 20.3 11.0 20.8 24.7 25.7 14.2 30.9 31.2 22.5 19.0 8.7 7.9 8.9 8.7 10.1 10.0 9.6 9.2 9.4 10.2 8.6 11.4 9.3 1.6 13.1 10.4 10.7 11.1 7.2 9.8 13.1 11.9 15.4 9.2 12.1 13.8 11.4 15.3 12.4 10.8 19.5 42.8 57.7 50.2 54.2 53.9 19.5 34.4 52.2 36.5 48.8 33.3 33.8 60.4 31.5 64.9 46.0 45.9 64.1 57.2 31.6 19.6 42.0 61.0 64.3 60.8 35.1 19.8 30.7 26.5 50.7 34.3 45.2 32.1 62.2 30.9 43.0 32.5 69.5 35.4 43.7 33.0 48.9 36.7 33.2 13.9 44.1 50.1 37.5 14.2 30.9 42.5 34.9 39.1 58.3 103.1 40.4 29.9 50.4 72.7 29.8 46.1 30.7 76.1 74.9 19.7 49.0 44.2 85.3 37.8 37.6 19.2 91.0 46.5 59.5 35.9 29.8 VAPA "hVAP-33, VAP-A" ENSG00000101558 "VAMP associated protein A" Q9P0L0 18 9914016-9960021 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009174 Approved Enhanced "Endoplasmic reticulum" NA NA 580000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 3: HMC-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "Endoplasmic reticulum" "HPA009174: AB_1080549" "unprognostic (4.03e-2)" "unprognostic (7.47e-2)" "unprognostic (9.36e-2)" "unprognostic (5.20e-2)" "unprognostic (2.00e-1)" "unprognostic (2.99e-2)" "unprognostic (4.79e-3)" "unprognostic (1.80e-1)" "unprognostic (5.39e-2)" "unprognostic (6.80e-3)" "unprognostic (2.99e-2)" "unprognostic (8.11e-2)" "prognostic favorable (5.72e-7)" "unprognostic (1.03e-1)" "unprognostic (1.66e-1)" "unprognostic (1.23e-1)" "unprognostic (5.77e-2)" 33.1 67.1 21.5 24.2 26.8 97.1 29.5 30.7 28.1 30.2 21.5 38.6 31.2 32.9 24.8 47.5 29.3 31.9 37.5 23.2 24.9 32.6 36.6 33.9 25.7 34.9 26.3 39.1 40.9 36.2 17.7 29.8 34.5 24.5 35.4 20.1 32.6 22.0 69.7 32.3 30.6 27.4 27.8 26.7 38.9 29.1 25.5 30.0 35.2 38.4 26.3 36.5 32.2 30.7 58.1 34.4 40.7 26.7 46.9 50.5 56.8 69.9 57.9 62.3 67.9 46.6 55.9 56.5 63.6 61.5 53.9 39.7 39.8 66.7 70.7 35.6 49.8 92.4 33.8 72.3 110.8 126.3 169.7 47.8 66.3 59.0 69.6 48.7 64.0 45.4 94.6 57.3 55.2 31.2 97.4 72.9 26.2 197.6 54.3 50.4 55.2 77.5 60.9 57.3 57.2 31.2 81.1 48.7 53.2 37.2 45.7 64.2 68.9 100.7 75.3 105.6 86.3 101.9 89.2 66.6 57.0 53.5 70.8 131.3 143.3 251.0 69.8 127.9 82.9 100.0 72.1 75.4 118.1 94.4 78.1 72.1 226.2 90.8 109.5 84.6 98.9 183.9 21.5 26.8 30.7 28.1 23.2 24.9 34.9 26.3 34.5 27.8 25.5 30.7 173.6 128.2 178.8 63.0 160.0 673.4 358.4 356.5 278.3 113.9 248.2 179.3 218.3 167.3 229.4 207.8 62.6 296.9 148.0 427.2 457.8 291.8 10.5 235.9 182.2 232.4 144.6 188.1 91.4 361.3 321.6 221.4 156.0 255.8 225.2 220.2 211.3 141.1 287.8 136.3 93.2 180.6 390.6 288.2 459.8 21.7 182.0 285.9 279.3 63.7 350.4 124.3 108.1 102.1 150.4 310.2 262.7 216.3 146.6 335.4 255.9 390.4 265.5 79.5 190.7 204.8 371.4 231.3 201.4 267.3 622.5 452.6 190.2 253.6 201.0 390.8 VAPB "ALS8, VAP-B, VAP-C" ENSG00000124164 "VAMP associated protein B and C" O95292 20 58389229-58451101 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction, Unfolded protein response" "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013144, CAB013722" Supported Enhanced "Endoplasmic reticulum" NA NA 240000 "Cluster 32: T-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Endoplasmic reticulum" "CAB013722: , HPA013144: AB_1858717" "unprognostic (3.28e-3)" "unprognostic (3.88e-2)" "unprognostic (1.02e-1)" "unprognostic (2.51e-2)" "unprognostic (9.36e-2)" "unprognostic (3.15e-2)" "unprognostic (4.76e-3)" "unprognostic (2.80e-1)" "unprognostic (4.47e-2)" "unprognostic (8.06e-3)" "unprognostic (3.11e-2)" "unprognostic (2.99e-1)" "prognostic favorable (1.08e-8)" "unprognostic (1.05e-1)" "unprognostic (5.31e-1)" "unprognostic (6.34e-3)" "unprognostic (2.99e-2)" 15.7 36.4 32.1 11.2 30.4 4.2 14.2 29.6 30.1 13.7 20.3 24.2 19.6 16.4 10.3 19.3 14.9 9.7 29.4 28.8 33.5 24.8 35.0 14.1 9.6 34.6 34.0 17.9 18.9 27.9 21.0 9.2 36.2 17.8 9.9 14.3 16.2 12.3 46.4 13.0 18.2 11.6 36.4 15.0 19.0 8.8 37.0 12.2 23.3 39.6 6.7 18.1 12.9 31.5 31.0 30.4 33.6 18.0 30.3 12.5 29.5 27.0 11.2 41.0 20.1 123.0 29.0 27.2 37.7 18.3 32.3 57.6 27.1 38.9 24.6 12.8 20.2 16.5 32.2 38.9 30.2 15.5 19.8 28.9 44.4 22.8 18.7 19.8 20.5 26.7 39.5 14.9 20.0 96.7 24.5 30.6 17.7 60.2 40.0 24.2 31.3 18.0 31.6 40.7 47.1 32.6 44.7 117.0 48.0 18.4 48.0 23.2 28.6 65.8 31.9 33.3 36.9 19.9 23.1 31.4 55.7 16.8 33.8 2.1 2.3 3.1 3.9 2.4 4.5 2.8 4.6 3.2 2.3 2.3 3.3 4.8 3.7 3.7 3.0 2.3 2.7 2.6 32.1 30.4 29.6 30.1 28.8 33.5 34.6 34.0 36.2 36.4 37.0 31.5 22.5 44.8 26.8 31.6 18.7 11.7 13.5 17.2 23.9 29.7 23.6 21.1 46.5 24.3 16.6 31.3 29.2 34.8 20.7 28.6 35.2 35.1 5.0 18.2 20.9 23.2 21.7 18.7 34.3 30.5 50.3 24.0 20.4 16.0 9.5 23.3 15.7 40.3 16.1 35.3 34.7 23.4 22.4 18.5 10.0 6.1 18.6 17.3 14.2 40.3 22.8 34.3 20.6 35.2 43.7 37.5 22.4 25.2 14.0 17.7 38.9 42.9 19.1 29.7 13.1 22.2 26.0 22.0 29.4 18.2 10.5 44.5 20.5 37.4 27.6 16.6 VIP ENSG00000146469 "Vasoactive intestinal peptide" P01282 6 152750797-152759765 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 72.2;lymphoid tissue: 155.5" "Group enriched" "Detected in some" 5 "Inhibitory neurons: 80.6;Melanocytes: 28.4" "Group enriched" "Detected in some" 6 "colorectal cancer: 3.7;pancreatic cancer: 4.3;stomach cancer: 2.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SH-SY5Y: 2.7;TIME: 1.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA017324, CAB018649, HPA072701, CAB079780" Supported Supported Approved "Endoplasmic reticulum" "Secreted to blood" NA NA 122000 "Cluster 14: B-cells - Humoral immune response" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "CAB018649: AB_2304501, CAB079780: , HPA017324: AB_1858754, HPA072701: AB_2686550" "unprognostic (9.58e-2)" "unprognostic (2.29e-2)" "unprognostic (2.60e-2)" "unprognostic (1.13e-1)" "unprognostic (3.34e-2)" "unprognostic (3.33e-2)" "unprognostic (2.48e-2)" "unprognostic (7.21e-2)" "unprognostic (2.22e-2)" "unprognostic (2.89e-2)" "unprognostic (2.36e-1)" "unprognostic (3.62e-1)" "unprognostic (2.92e-3)" "unprognostic (7.47e-2)" "unprognostic (1.94e-1)" "unprognostic (1.30e-1)" "unprognostic (5.90e-2)" 2.7 12.2 5.5 155.5 7.9 0.1 1.9 4.9 10.9 1.8 4.6 72.2 16.6 1.2 0.4 4.3 1.5 3.7 4.3 7.3 28.7 2.5 1.1 3.4 0.4 6.9 40.0 0.8 8.3 0.3 0.8 0.6 7.7 2.7 61.4 1.0 0.5 0.5 1.4 0.4 45.8 41.6 4.8 9.7 22.2 1.0 11.9 0.1 2.3 1.7 0.1 1.6 9.4 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.8 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 7.9 4.9 10.9 7.3 28.7 6.9 40.0 7.7 4.8 11.9 5.9 2.5 0.0 0.0 3.3 0.2 0.4 0.0 0.0 0.0 1.3 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.0 2.8 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 80.6 0.0 0.0 0.3 0.0 6.5 0.0 0.0 28.4 4.7 0.0 0.0 0.0 2.5 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 VKORC1 VKCFD2 ENSG00000167397 "Vitamin K epoxide reductase complex subunit 1" Q9BQB6 16 31090842-31095980 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 454.9" "Cell type enhanced" "Detected in all" "Hepatocytes: 749.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 638.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042720 Approved Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "Endoplasmic reticulum" "HPA042720: AB_10961864" "unprognostic (5.99e-2)" "unprognostic (2.98e-1)" "unprognostic (7.11e-3)" "unprognostic (7.68e-3)" "unprognostic (5.49e-2)" "unprognostic (3.23e-3)" "unprognostic (3.02e-2)" "unprognostic (2.32e-2)" "unprognostic (2.42e-1)" "unprognostic (2.66e-1)" "unprognostic (1.04e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.09e-10)" "unprognostic (1.11e-2)" "unprognostic (6.65e-2)" "unprognostic (3.12e-2)" "unprognostic (9.66e-2)" 99.4 107.6 56.0 38.4 60.4 55.2 87.0 60.3 73.5 111.0 64.9 97.0 44.2 109.9 87.2 51.8 90.8 58.9 99.1 57.4 59.3 122.7 454.9 77.4 35.8 64.4 59.5 115.1 168.0 51.3 115.7 45.6 63.8 76.3 41.1 23.0 92.4 69.8 34.4 81.1 82.3 84.7 59.9 62.2 88.1 55.6 68.5 35.0 76.3 32.2 32.6 100.6 88.0 64.8 73.6 187.7 57.2 165.4 638.0 389.6 68.2 269.0 229.3 128.9 218.5 79.0 83.3 54.9 141.6 331.6 87.2 66.2 79.4 103.5 139.5 81.9 204.8 52.5 239.9 378.2 103.1 104.1 74.1 225.0 54.2 173.4 146.6 336.8 141.0 78.2 70.3 130.6 253.6 271.1 74.4 205.9 106.8 98.0 175.9 132.7 160.3 286.8 127.7 61.8 119.5 146.9 118.7 84.2 137.8 91.2 138.3 123.9 126.8 171.1 61.5 159.6 101.9 76.1 80.2 50.7 445.8 174.5 90.8 77.0 127.5 196.2 118.1 94.7 116.8 91.7 116.7 119.4 127.6 102.6 102.9 101.4 104.0 84.2 98.2 157.4 143.1 112.8 56.0 60.4 60.3 73.5 57.4 59.3 64.4 59.5 63.8 59.9 68.5 64.8 95.1 57.7 51.0 5.9 30.6 84.6 68.0 157.0 10.8 12.3 93.3 117.3 20.9 141.5 64.3 108.5 8.4 85.7 48.1 34.3 62.6 204.2 6.1 25.8 83.7 89.5 67.1 32.4 8.8 129.4 293.6 132.8 10.7 48.8 55.3 60.3 118.9 749.9 184.1 10.1 7.5 44.2 46.8 80.1 94.3 13.9 158.1 66.9 115.6 5.6 107.4 68.8 51.5 6.6 17.6 103.8 28.2 172.3 29.5 59.5 152.9 204.6 33.4 19.3 59.2 78.4 99.8 30.6 34.2 10.7 112.0 39.5 39.7 82.4 49.0 55.2 VKORC1L1 ENSG00000196715 "Vitamin K epoxide reductase complex subunit 1 like 1" Q8N0U8 7 65873074-65959563 "Enzymes, FDA approved drug targets, Predicted membrane proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053954 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" "Endoplasmic reticulum" "HPA053954: AB_2682319" "unprognostic (3.01e-1)" "unprognostic (1.76e-3)" "unprognostic (4.64e-2)" "unprognostic (4.65e-2)" "unprognostic (3.00e-3)" "unprognostic (7.15e-3)" "unprognostic (1.30e-3)" "unprognostic (8.84e-3)" "unprognostic (5.12e-2)" "unprognostic (5.59e-2)" "unprognostic (9.23e-3)" "unprognostic (1.07e-1)" "unprognostic (1.59e-2)" "unprognostic (1.17e-1)" "unprognostic (7.03e-3)" "unprognostic (4.30e-1)" "unprognostic (5.06e-2)" 54.0 11.1 8.1 11.2 9.0 4.3 23.7 8.3 12.1 12.0 3.7 12.4 11.1 12.3 10.6 12.5 10.0 10.0 12.1 10.1 9.2 10.0 22.9 18.4 8.7 18.1 10.5 17.3 9.7 33.6 6.7 12.0 10.5 12.0 12.5 11.5 10.9 12.4 21.6 12.8 11.6 11.6 8.9 7.4 12.8 9.1 8.5 9.7 13.9 15.3 8.7 11.9 9.6 9.6 46.8 29.5 23.4 29.5 72.6 28.6 42.3 49.5 31.8 29.0 29.1 28.7 44.9 40.4 39.0 35.7 43.9 31.2 33.6 20.1 47.9 25.5 33.1 27.6 25.4 24.7 35.4 38.7 20.3 23.2 25.3 29.5 40.7 22.5 29.2 22.6 59.0 30.0 34.9 18.3 31.8 44.8 56.1 43.8 22.0 34.5 34.0 50.5 28.0 18.5 28.0 39.8 38.3 68.5 21.8 32.8 34.5 29.5 33.3 46.6 32.0 29.5 51.0 26.9 47.1 46.1 28.6 43.0 41.6 2.0 1.1 2.7 1.2 1.1 1.0 1.3 1.5 1.4 1.3 1.1 0.9 0.9 1.3 2.9 2.2 3.5 1.5 0.7 8.1 9.0 8.3 12.1 10.1 9.2 18.1 10.5 10.5 8.9 8.5 9.6 19.5 73.7 41.7 16.6 5.5 24.9 18.6 16.2 9.6 21.8 18.6 15.9 21.5 27.1 24.2 16.5 12.5 12.5 10.0 27.1 5.9 18.1 39.0 13.7 23.8 17.1 13.8 26.1 42.7 24.8 21.2 22.6 19.4 25.3 5.1 24.1 10.8 46.9 16.0 30.3 36.6 26.4 20.3 6.6 10.2 9.1 17.7 12.9 7.2 28.1 10.0 11.6 7.2 26.7 34.6 31.6 8.2 18.4 15.6 36.3 14.4 11.4 11.7 20.2 6.6 24.9 26.4 18.5 7.2 17.9 32.0 8.8 6.6 10.8 20.3 22.6 VRK2 ENSG00000028116 "VRK serine/threonine kinase 2" Q86Y07 2 57907629-58159920 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 9 "Oligodendrocytes: 540.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046459, HPA047503" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 70: Brain - Nervous system development" "Cluster 44: HDLM-2 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Endoplasmic reticulum" "CAB046459: AB_1858773, HPA047503: AB_2680071" "unprognostic (1.87e-1)" "unprognostic (5.84e-2)" "unprognostic (4.65e-2)" "unprognostic (1.33e-3)" "unprognostic (1.27e-1)" "unprognostic (1.60e-2)" "prognostic unfavorable (6.32e-6)" "unprognostic (3.90e-2)" "unprognostic (4.76e-2)" "unprognostic (2.96e-2)" "prognostic unfavorable (4.65e-4)" "unprognostic (1.36e-1)" "prognostic unfavorable (4.66e-5)" "unprognostic (3.48e-1)" "unprognostic (1.62e-1)" "unprognostic (2.99e-1)" "unprognostic (3.56e-1)" 14.8 13.2 14.9 20.2 26.4 18.8 17.2 15.1 16.2 10.8 9.3 14.0 10.9 15.3 16.7 19.5 13.4 11.9 15.6 12.8 16.0 10.7 16.8 15.9 22.5 23.9 21.1 10.7 19.7 14.7 7.6 14.6 23.0 14.2 16.4 4.8 13.8 11.4 14.3 13.3 11.0 19.4 14.8 18.0 13.7 13.3 18.9 12.7 18.6 15.1 26.0 14.7 12.6 40.6 37.1 24.3 2.7 16.3 16.7 30.6 48.4 32.8 33.3 22.7 22.9 49.8 38.5 44.3 43.0 29.8 37.1 27.4 34.9 36.7 33.7 80.9 23.1 50.9 19.0 35.8 27.8 44.1 29.0 17.7 42.6 36.3 52.8 26.1 64.9 6.2 50.2 28.5 38.2 21.2 0.3 32.9 29.9 56.9 11.6 49.4 12.0 30.6 36.8 30.2 9.4 0.3 52.5 31.2 27.5 26.2 22.0 26.1 37.0 0.5 74.4 20.6 0.6 40.5 33.9 24.0 18.2 52.7 38.4 31.0 24.5 35.3 15.1 32.2 18.4 30.6 14.2 17.7 25.5 31.7 10.6 13.6 9.0 18.7 34.3 26.4 18.5 15.4 14.9 26.4 15.1 16.2 12.8 16.0 23.9 21.1 23.0 14.8 18.9 40.6 17.9 22.4 11.2 1.3 26.4 9.8 12.6 21.8 14.8 1.0 14.0 10.2 21.8 7.2 22.4 18.4 0.0 21.2 13.7 6.5 15.6 27.1 23.0 12.7 10.9 15.8 6.6 39.1 2.7 26.2 21.1 14.0 16.3 12.7 17.7 9.6 8.9 8.4 18.4 0.0 4.7 5.1 30.5 19.1 19.1 8.4 5.9 26.2 10.6 54.4 41.7 5.3 16.5 32.2 540.8 24.8 8.7 6.0 25.7 18.4 2.5 9.5 30.7 4.0 6.6 7.4 14.3 22.0 10.9 19.2 8.4 19.4 16.5 6.8 7.9 16.4 VSTM5 "C11orf90, LOC387804" ENSG00000214376 "V-set and transmembrane domain containing 5" A8MXK1 11 93818232-93850618 "Predicted membrane proteins" "Developmental protein" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 3.7;placenta: 4.4" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 22.3;Excitatory neurons: 5.2;Inhibitory neurons: 9.2;Syncytiotrophoblasts: 5.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1.2;OE19: 3.7;PC-3: 5.4;SH-SY5Y: 2.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029525, HPA063591" Uncertain Uncertain "Endoplasmic reticulum" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 47: Cytotrophoblasts - Unknown function" "Endoplasmic reticulum" "HPA029525: AB_10600789, HPA063591: AB_2732704" "unprognostic (1.26e-1)" "unprognostic (4.48e-3)" "unprognostic (2.78e-1)" "unprognostic (1.54e-4)" "unprognostic (2.45e-2)" "unprognostic (9.91e-2)" "unprognostic (8.56e-2)" "unprognostic (1.37e-2)" "unprognostic (1.68e-2)" "unprognostic (1.04e-1)" "unprognostic (2.52e-2)" "unprognostic (2.13e-1)" "unprognostic (1.31e-1)" "unprognostic (3.53e-2)" "unprognostic (2.37e-1)" "unprognostic (3.29e-1)" "unprognostic (1.26e-1)" 0.2 0.2 2.2 0.1 1.9 0.0 0.4 1.0 3.4 1.1 0.1 1.1 0.1 0.4 1.2 0.1 0.2 0.4 0.1 1.8 3.7 0.8 0.0 0.1 0.0 3.1 2.0 0.1 0.5 0.1 0.6 4.4 3.3 0.5 1.7 0.5 0.4 0.4 0.0 0.1 0.7 0.7 1.4 0.0 1.9 0.2 3.3 0.0 0.1 0.0 0.1 0.2 0.1 2.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.1 0.5 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 5.4 0.0 0.0 0.1 0.0 0.1 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.9 1.0 3.4 1.8 3.7 3.1 2.0 3.3 1.4 3.3 2.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.9 0.5 0.5 0.3 0.0 0.1 0.0 0.0 22.3 0.1 1.1 0.0 0.4 0.0 0.3 0.2 0.1 0.0 0.0 5.2 3.0 0.7 0.3 1.5 0.7 0.0 0.1 0.0 0.0 1.5 0.0 9.2 1.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.2 1.1 2.1 0.4 0.0 0.1 0.5 1.5 0.0 0.3 0.0 0.0 0.2 0.0 0.2 0.0 0.1 5.9 0.0 0.0 1.6 0.1 WDR83OS "Asterix, C19orf56, PTD008" ENSG00000105583 "WD repeat domain 83 opposite strand" Q9Y284 19 12668073-12669415 "Predicted membrane proteins, Transporters" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065685 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Endoplasmic reticulum" "HPA065685: AB_2685531" "unprognostic (1.73e-1)" "unprognostic (5.37e-3)" "unprognostic (1.03e-1)" "unprognostic (4.86e-2)" "unprognostic (1.27e-1)" "unprognostic (3.29e-2)" "unprognostic (7.47e-2)" "prognostic favorable (2.09e-4)" "unprognostic (1.71e-1)" "prognostic favorable (8.84e-4)" "unprognostic (4.17e-3)" "unprognostic (1.09e-1)" "unprognostic (7.87e-3)" "unprognostic (2.67e-1)" "unprognostic (1.02e-1)" "unprognostic (1.02e-1)" "unprognostic (8.34e-2)" 152.2 219.2 204.0 80.1 213.4 203.3 156.9 213.2 226.5 164.0 199.2 138.5 103.9 146.9 276.1 174.0 223.2 138.0 206.8 198.6 212.5 194.9 189.2 133.3 128.7 209.9 205.9 226.2 210.0 204.7 164.8 119.7 211.1 160.6 151.4 50.2 180.9 135.9 226.7 175.1 128.5 169.6 216.9 146.5 164.7 80.4 210.8 129.8 190.1 234.1 174.2 164.4 144.8 223.7 190.9 204.4 223.1 252.8 338.2 267.0 96.4 135.3 230.3 211.6 181.7 170.0 161.1 86.2 310.0 390.4 143.5 150.9 242.7 255.9 175.2 180.9 333.0 107.4 170.3 259.6 262.1 183.5 148.5 287.1 343.2 208.0 243.7 309.9 265.2 161.2 196.2 196.3 253.5 661.5 136.8 399.3 187.7 254.4 584.9 110.0 117.7 310.1 241.7 217.2 182.3 278.6 155.2 162.4 193.5 148.2 197.6 295.1 156.7 289.8 78.2 317.2 205.8 342.4 428.4 126.5 245.4 313.2 189.0 612.8 502.8 492.3 329.2 469.3 312.0 445.2 308.6 336.5 466.7 394.4 280.0 305.8 485.8 451.4 503.7 319.2 396.0 635.4 204.0 213.4 213.2 226.5 198.6 212.5 209.9 205.9 211.1 216.9 210.8 223.7 198.5 80.1 54.6 11.8 156.8 171.7 193.7 391.7 272.0 42.3 310.7 424.2 129.4 168.7 204.5 342.1 27.1 435.7 153.8 233.0 401.1 255.5 7.9 128.6 184.0 185.7 195.3 126.4 10.5 255.8 333.8 205.2 162.6 162.7 147.9 239.7 183.1 314.3 287.5 50.5 10.6 282.6 301.1 212.5 230.2 22.7 170.6 209.3 297.1 13.1 254.5 264.8 179.2 13.0 39.4 243.4 295.7 144.8 256.0 230.9 398.1 586.3 103.6 55.7 98.6 140.9 187.6 87.3 98.4 353.6 221.3 405.1 172.2 279.8 262.4 241.1 ZFYVE1 "DFCP1, KIAA1589, PPP1R172, TAFF1, ZNFN2A1" ENSG00000165861 "Zinc finger FYVE-type containing 1" Q9HBF4 14 72969451-73027131 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 45.8;Late spermatids: 108.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002898 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 25: Spermatids - Spermatogenesis" "Endoplasmic reticulum" "HPA002898: AB_1080653" "unprognostic (2.19e-1)" "unprognostic (1.50e-1)" "unprognostic (4.65e-2)" "unprognostic (1.23e-1)" "unprognostic (3.47e-1)" "unprognostic (2.40e-2)" "unprognostic (7.42e-3)" "unprognostic (6.82e-2)" "unprognostic (1.05e-2)" "unprognostic (2.40e-2)" "unprognostic (1.83e-2)" "unprognostic (1.53e-1)" "prognostic favorable (5.07e-12)" "unprognostic (4.03e-2)" "unprognostic (1.67e-1)" "unprognostic (2.95e-1)" "unprognostic (7.48e-2)" 11.8 13.5 9.8 5.8 11.3 12.3 9.3 9.8 9.6 8.6 7.4 11.1 9.3 9.1 5.7 13.2 7.2 8.1 9.4 9.4 10.9 12.1 11.2 8.2 7.1 11.3 10.8 9.6 7.7 11.1 6.4 9.4 11.1 7.7 6.6 9.1 8.3 7.1 16.3 13.2 9.1 9.4 10.1 8.2 7.7 16.9 11.2 8.1 12.5 13.7 7.3 9.2 9.3 10.9 8.0 11.3 10.6 10.3 26.9 18.5 7.2 11.5 17.9 12.4 19.5 7.8 6.9 4.2 8.6 14.7 14.6 5.7 7.5 7.1 12.7 16.6 4.2 5.2 5.3 5.5 23.0 1.9 18.7 24.3 18.6 12.2 10.2 18.7 19.7 11.3 4.8 10.8 16.3 9.5 8.3 5.9 5.0 6.4 10.3 11.7 7.4 5.2 11.2 8.3 5.7 9.9 10.4 10.5 12.0 14.6 14.3 7.1 22.0 22.7 9.3 6.4 3.9 15.7 16.9 5.9 12.4 4.2 10.7 2.2 7.0 9.6 6.7 6.3 4.6 3.0 3.4 4.6 6.1 3.0 3.6 4.5 10.9 3.7 5.9 3.5 5.7 5.5 9.8 11.3 9.8 9.6 9.4 10.9 11.3 10.8 11.1 10.1 11.2 10.9 5.6 12.8 5.5 10.1 5.1 6.5 1.8 3.6 8.0 6.2 6.8 4.1 7.8 1.5 3.7 9.2 4.2 3.7 6.8 10.2 1.9 6.4 45.8 6.5 6.3 6.3 7.2 23.1 14.8 5.3 4.4 6.3 7.7 7.0 8.2 9.7 7.1 8.6 5.5 16.8 14.3 7.6 4.1 7.1 3.3 108.9 8.7 7.1 12.4 10.3 6.6 7.6 6.2 13.0 20.6 6.1 9.7 9.1 6.9 3.3 13.1 8.3 3.5 5.4 0.0 5.5 7.6 5.5 3.6 9.0 5.4 9.3 6.4 7.5 4.5 6.2 ZNF501 "MGC21738, ZNF52" ENSG00000186446 "Zinc finger protein 501" Q96CX3 3 44729596-44737083 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Horizontal cells: 10.1;Spermatogonia: 11.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC TERT1: 3.5" HPA044161 Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 5: NTERA-2 - Transcription" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Endoplasmic reticulum" "HPA044161: AB_2678841" "unprognostic (8.89e-2)" "unprognostic (5.04e-2)" "unprognostic (9.24e-2)" "unprognostic (3.03e-2)" "unprognostic (1.19e-2)" "unprognostic (3.46e-3)" "unprognostic (2.37e-1)" "unprognostic (2.25e-2)" "unprognostic (4.02e-2)" "unprognostic (1.61e-1)" "unprognostic (2.86e-1)" "unprognostic (2.81e-1)" "unprognostic (3.81e-4)" "unprognostic (1.18e-1)" "unprognostic (4.48e-1)" "unprognostic (1.09e-2)" "unprognostic (3.02e-2)" 1.6 0.5 1.0 0.7 1.2 0.1 1.8 1.4 1.1 1.4 0.3 1.9 0.4 2.0 0.5 0.9 1.6 0.6 1.2 0.9 1.0 1.4 0.4 0.9 0.8 1.0 1.1 2.1 1.4 0.5 0.8 1.2 1.0 1.7 0.8 2.0 1.1 1.4 1.2 1.1 1.0 1.3 1.1 1.1 1.1 1.9 1.1 0.8 1.3 1.2 0.9 1.6 1.2 1.0 0.0 0.0 1.1 0.0 2.0 3.5 0.4 1.3 1.2 1.4 1.6 0.5 0.5 1.0 0.0 0.6 1.0 0.4 0.0 0.5 1.3 0.0 0.7 0.0 0.1 1.0 2.8 0.0 0.0 2.0 1.3 1.6 0.1 0.4 0.9 0.0 0.0 0.0 0.4 0.0 0.4 0.0 2.6 0.6 0.0 0.7 0.0 0.5 1.1 0.7 1.4 0.9 0.8 0.8 0.5 2.1 0.0 0.1 0.5 0.0 1.2 1.3 1.0 2.2 1.6 0.0 0.0 0.0 1.7 0.5 0.2 0.9 0.7 0.2 0.9 0.8 0.6 0.7 0.3 1.0 0.9 0.6 0.3 0.8 0.3 0.3 0.7 0.3 1.0 1.2 1.4 1.1 0.9 1.0 1.0 1.1 1.0 1.1 1.1 1.0 3.5 0.0 0.5 3.6 2.4 0.9 1.5 1.5 2.8 3.5 2.0 1.8 3.5 1.5 1.8 3.7 2.1 1.9 0.9 0.5 0.0 2.9 1.1 1.3 2.5 2.3 1.2 3.4 1.3 1.9 2.0 3.2 3.1 1.1 0.0 3.1 2.2 1.0 1.6 10.1 3.3 1.0 2.0 1.3 0.8 1.9 1.5 0.9 0.0 1.0 1.5 9.0 5.2 3.5 3.9 1.9 0.4 1.5 3.1 0.9 0.7 1.1 0.9 4.0 6.6 3.1 3.8 7.0 11.3 1.8 1.6 0.3 1.8 2.5 1.3 0.8 ZNF804A C2orf10 ENSG00000170396 "Zinc finger protein 804A" Q7Z570 2 184598529-184939492 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 5.0;retina: 3.8" "Group enriched" "Detected in many" 9 "Excitatory neurons: 267.9;Inhibitory neurons: 676.0;Oligodendrocyte precursor cells: 186.5" "Cancer enhanced" "Detected in single" "glioma: 0.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 28.3;RH-30: 17.7;THP-1: 13.9;U-698: 20.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029195 Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 6: Brain - Smell perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "HPA029195: AB_10603011" "unprognostic (1.10e-1)" "unprognostic (1.00e-1)" "unprognostic (1.06e-2)" "unprognostic (2.05e-2)" "unprognostic (1.08e-2)" "unprognostic (1.26e-2)" "unprognostic (1.50e-1)" "unprognostic (2.41e-1)" "unprognostic (4.45e-1)" "unprognostic (2.38e-2)" "unprognostic (2.83e-2)" "unprognostic (5.20e-2)" "unprognostic (4.98e-4)" "unprognostic (6.21e-2)" "unprognostic (4.04e-1)" "unprognostic (8.45e-2)" "unprognostic (4.93e-2)" 0.0 0.2 1.6 1.0 4.7 0.6 0.0 4.7 5.0 0.1 0.0 0.2 0.5 0.0 0.0 0.1 0.0 1.1 0.0 3.3 3.5 0.6 0.1 0.3 0.9 2.1 0.8 0.2 0.0 0.0 0.0 0.1 1.6 1.2 0.3 3.8 0.1 1.3 0.0 0.0 1.2 0.1 0.5 0.6 0.4 0.2 1.8 0.0 1.4 0.0 1.0 0.4 0.0 0.6 0.0 0.0 1.5 0.0 0.0 0.0 0.0 2.9 6.3 2.1 1.9 0.0 0.0 28.3 0.0 0.0 2.6 0.0 0.4 0.0 4.6 0.2 0.0 7.4 1.0 0.1 10.0 7.1 0.0 3.1 0.0 0.0 1.6 3.2 4.9 0.0 0.0 1.2 0.0 0.0 0.0 6.8 0.0 0.0 4.8 0.0 17.7 1.1 0.0 0.0 0.4 3.1 0.0 0.0 0.0 0.1 0.0 13.9 0.0 6.8 0.1 0.2 2.8 3.1 0.0 20.5 7.7 2.0 2.2 0.0 0.2 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.6 4.7 4.7 5.0 3.3 3.5 2.1 0.8 1.6 0.5 1.8 0.6 0.1 0.0 0.6 13.4 9.2 0.0 0.0 0.0 0.0 38.0 0.1 0.1 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.2 2.2 0.6 0.0 5.5 267.9 0.0 0.0 2.2 0.0 0.3 0.0 0.9 0.0 0.2 2.9 3.3 676.0 1.1 0.0 1.6 3.7 0.6 0.3 5.4 0.0 6.5 3.5 1.0 0.0 186.5 5.4 0.0 0.0 0.0 21.5 0.0 1.5 0.1 0.0 2.9 6.6 0.1 0.7 5.3 1.2 0.0 0.0 0.0 0.5 1.1 2.7 0.1 ZSCAN21 "DKFZp434L134, NY-REN-21, Zipro1, ZNF38" ENSG00000166529 "Zinc finger and SCAN domain containing 21" Q9Y5A6 7 100049774-100065040 "Predicted intracellular proteins, Transcription factors" "Differentiation, Meiosis, Spermatogenesis, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016948, HPA023591" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "Endoplasmic reticulum" "HPA016948: , HPA023591: AB_1859037" "unprognostic (2.44e-3)" "unprognostic (3.77e-1)" "unprognostic (2.84e-3)" "unprognostic (1.36e-1)" "unprognostic (4.45e-2)" "unprognostic (2.00e-1)" "unprognostic (1.97e-1)" "unprognostic (7.42e-3)" "unprognostic (8.59e-3)" "unprognostic (3.76e-2)" "unprognostic (1.67e-3)" "unprognostic (3.10e-2)" "unprognostic (3.13e-3)" "unprognostic (1.79e-1)" "unprognostic (3.24e-2)" "prognostic unfavorable (4.71e-4)" "unprognostic (6.09e-2)" 7.8 7.8 10.6 4.5 12.3 6.1 8.0 12.6 11.7 10.3 10.2 11.2 4.6 9.8 9.2 5.7 10.6 6.0 7.6 10.5 10.7 9.6 13.1 6.2 6.2 11.4 11.6 9.9 10.0 7.0 7.6 8.0 11.3 10.8 5.3 9.3 10.3 7.2 14.1 7.0 6.9 7.8 10.6 7.4 9.0 12.2 12.0 7.1 8.3 12.9 4.9 9.4 7.4 14.1 5.9 9.8 16.0 18.7 14.8 9.5 13.1 6.7 10.3 13.0 13.0 7.8 6.7 6.4 8.2 7.9 22.1 5.3 14.5 9.7 12.9 8.5 11.9 5.8 8.6 7.3 16.0 8.4 2.3 11.3 16.8 12.7 21.1 10.8 10.5 13.0 14.0 5.4 9.7 15.1 14.0 13.8 19.9 8.2 7.3 9.5 12.8 7.8 10.8 9.2 8.2 20.9 9.2 19.4 12.9 22.6 7.8 7.0 4.6 11.8 14.6 10.4 9.4 10.7 10.6 14.1 5.5 5.3 16.1 12.9 6.0 12.9 9.9 5.8 10.8 6.6 6.0 9.0 6.3 6.5 6.6 7.5 0.8 10.7 3.9 5.9 7.4 4.9 10.6 12.3 12.6 11.7 10.5 10.7 11.4 11.6 11.3 10.6 12.0 14.1 5.1 3.2 5.1 5.5 4.3 1.5 3.4 4.1 5.2 6.0 3.5 3.6 1.6 2.8 4.4 3.7 2.1 16.6 10.6 2.9 7.9 7.1 2.7 4.0 7.7 4.7 1.8 11.0 3.7 4.0 6.5 5.4 2.6 3.8 2.5 8.0 3.6 5.2 5.2 10.1 4.1 2.5 8.2 2.5 2.1 0.7 5.9 2.9 3.6 7.5 3.0 16.5 3.1 7.1 7.5 4.4 5.0 9.8 3.4 4.0 3.2 11.9 2.5 5.9 0.0 7.7 6.7 14.1 19.7 2.9 3.8 17.6 2.9 8.0 2.8 1.7