Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ABCB1 "ABC20, CD243, CLCS, GP170, MDR1, P-gp, PGY1" ENSG00000085563 "ATP binding cassette subfamily B member 1" P08183 7 87503017-87713323 "Cancer-related genes, CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 101.7;intestine: 70.7" "Cell type enhanced" "Detected in many" "Cholangiocytes: 95.8;Distal enterocytes: 109.9;Microglial cells: 570.6;Paneth cells: 106.2;Proximal enterocytes: 204.6" "Cancer enhanced" "Detected in many" "renal cancer: 14.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 27.2;NK-cell: 17.9" "Group enriched" "Detected in many" 9 "NK-cells: 17.9;T-cells: 27.2" "Cell line enhanced" "Detected in some" "CACO-2: 67.3;HEK 293: 20.4;HEL: 37.7;Hep G2: 18.5;RPTEC TERT1: 24.2;SH-SY5Y: 78.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 12.2" "CAB001716, HPA002199, HPA074614" Enhanced Approved "Nucleoplasm,Plasma membrane,Focal adhesion sites" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Plasma membrane" "Focal adhesion sites" "CAB001716: , HPA002199: AB_1844428, HPA074614: " "unprognostic (5.38e-3)" "unprognostic (2.45e-2)" "unprognostic (1.42e-1)" "unprognostic (1.06e-1)" "unprognostic (2.25e-2)" "unprognostic (9.99e-5)" "unprognostic (2.23e-3)" "unprognostic (5.65e-3)" "unprognostic (1.14e-1)" "unprognostic (5.17e-2)" "prognostic favorable (3.33e-4)" "unprognostic (5.19e-1)" "prognostic favorable (2.95e-4)" "unprognostic (2.06e-1)" "unprognostic (1.50e-1)" "unprognostic (3.83e-1)" "unprognostic (6.12e-2)" 2.6 101.7 14.1 3.9 13.6 1.9 3.6 13.7 17.6 6.4 5.3 16.6 26.4 11.0 3.6 3.1 5.0 15.5 1.9 15.3 15.6 33.7 28.0 6.4 3.2 17.6 14.4 2.2 2.0 1.4 0.5 2.3 19.7 4.2 18.2 2.2 1.2 3.1 0.2 1.5 70.7 9.8 15.1 4.2 2.1 0.9 19.3 2.7 1.9 1.4 3.5 3.6 1.7 14.3 0.0 0.0 3.7 0.0 0.0 0.0 0.1 0.1 4.3 0.0 0.0 67.3 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 20.4 37.7 4.2 18.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 3.2 0.0 0.1 0.0 0.2 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 24.2 0.2 0.9 78.9 0.0 0.0 0.1 0.1 0.0 0.0 0.6 0.0 4.0 0.0 0.9 7.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 11.1 0.0 27.2 0.8 2.7 6.8 0.0 2.5 1.7 6.6 0.2 17.9 0.0 0.1 0.0 2.5 14.1 13.6 13.7 17.6 15.3 15.6 17.6 14.4 19.7 15.1 19.3 14.3 17.1 0.0 3.0 3.9 9.9 0.8 0.1 0.0 1.2 1.9 0.4 3.9 3.0 95.8 0.6 49.7 0.0 5.8 24.7 109.9 5.9 13.8 27.3 0.6 0.6 52.9 0.0 7.8 16.1 1.9 0.2 3.7 0.0 0.7 3.8 0.3 2.5 38.4 0.4 0.0 11.4 15.8 0.0 0.6 1.2 3.8 0.9 1.6 0.0 570.6 0.2 0.2 32.0 6.0 3.2 8.1 106.2 0.0 4.6 0.2 204.6 57.7 0.7 1.1 0.0 0.4 1.3 0.4 0.9 0.2 0.6 9.9 24.5 0.1 19.9 0.3 ABCB4 "GBD1, MDR2, MDR3, PFIC-3, PGY3" ENSG00000005471 "ATP binding cassette subfamily B member 4" P21439 7 87401696-87480435 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "liver: 123.2" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 256.1" "Cancer enriched" "Detected in some" 11 "liver cancer: 16.3" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 5 "memory B-cell: 4.4;naive B-cell: 8.1" "Lineage enriched" "Detected in many" 7 "B-cells: 8.1" "Group enriched" "Detected in some" 5 "SH-SY5Y: 12.9;WM-115: 25.7" "Low region specificity" "Detected in many" "HPA049395, HPA053288" Enhanced Approved "Nucleoplasm,Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 62: Liver - Hemostasis" "Cluster 17: WM-115 - Nervous system development" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Plasma membrane, Actin filaments" "Focal adhesion sites" "HPA049395: AB_2680745, HPA053288: AB_2682102" "unprognostic (7.92e-2)" "unprognostic (8.87e-2)" "unprognostic (1.97e-1)" "unprognostic (1.90e-1)" "unprognostic (8.95e-2)" "unprognostic (1.06e-2)" "unprognostic (2.35e-3)" "unprognostic (9.91e-2)" "unprognostic (3.53e-1)" "unprognostic (1.19e-1)" "unprognostic (2.44e-3)" "unprognostic (8.43e-2)" "unprognostic (2.83e-2)" "unprognostic (8.01e-3)" "unprognostic (7.12e-2)" "unprognostic (2.11e-2)" "unprognostic (2.47e-1)" 0.7 7.4 0.8 2.5 0.6 0.9 0.5 0.6 0.9 0.3 0.4 1.1 0.4 0.2 0.6 0.6 0.2 0.8 6.6 0.8 0.6 0.6 123.2 0.2 5.9 0.9 0.6 0.4 0.1 0.0 0.2 0.2 1.0 0.5 1.2 0.4 0.6 0.4 7.5 1.4 2.1 0.3 0.6 5.0 0.6 1.0 0.7 0.7 0.5 4.8 5.2 1.2 0.5 0.7 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.4 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.2 12.9 0.0 0.6 2.6 0.5 0.2 0.6 0.0 0.2 1.7 0.1 0.0 0.0 0.0 3.2 0.2 0.0 25.7 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 1.2 8.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.8 0.6 0.6 0.9 0.8 0.6 0.9 0.6 1.0 0.6 0.7 0.7 1.3 0.0 0.5 0.3 22.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 10.2 0.0 0.0 1.8 0.0 1.1 0.1 0.2 0.0 0.1 0.6 0.2 0.2 1.0 0.0 0.4 0.6 0.0 0.3 2.0 0.0 0.2 0.0 0.0 3.3 256.1 0.5 38.7 1.8 0.0 0.0 5.0 1.2 0.4 0.0 1.0 10.6 3.7 0.1 0.0 0.0 0.5 0.0 0.1 0.1 0.4 0.3 0.0 0.5 0.7 0.0 0.2 0.0 0.6 1.2 1.2 0.2 0.0 0.4 0.1 0.7 0.0 0.2 0.0 AC093827.5 ENSG00000285458 "Novel protein" 4 86886472-86936178 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 12.8;Alveolar cells type 2: 3.1;Distal tubular cells: 5.9;Respiratory ciliated cells: 8.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Karpas-707: 5.1" HPA057434 Uncertain Approved "Focal adhesion sites,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" "Focal adhesion sites" Cytosol "HPA057434: AB_2683438" 1.3 1.2 2.2 0.7 2.5 1.1 1.9 3.6 3.3 1.2 1.3 0.9 1.0 1.1 2.0 1.3 1.0 0.8 2.7 2.6 2.2 1.7 0.7 1.0 0.5 2.0 2.0 1.1 0.9 1.6 0.9 2.1 1.4 1.2 2.0 1.4 0.9 3.4 2.8 1.0 1.0 1.0 0.9 1.3 1.9 2.1 0.6 2.2 3.7 0.4 0.9 3.6 1.6 1.0 0.4 0.7 1.5 1.3 0.6 1.5 1.6 0.5 0.7 0.7 2.6 0.2 1.3 1.0 1.2 1.1 0.7 0.9 0.6 1.2 0.6 1.2 1.3 0.7 0.8 2.1 0.8 0.9 2.3 0.5 1.7 0.8 0.4 0.6 0.9 5.1 0.3 0.5 0.9 0.7 1.0 1.6 0.5 1.6 0.6 1.3 1.5 1.1 0.5 0.8 1.1 1.0 1.3 0.7 2.0 1.3 0.6 1.1 1.5 0.5 0.7 2.3 1.1 2.3 0.9 1.0 0.6 0.3 0.3 0.3 0.3 0.3 0.5 0.3 0.2 0.3 0.3 0.3 0.3 0.6 0.4 0.4 0.2 0.5 0.1 0.1 2.2 2.5 3.6 3.3 2.6 2.2 2.0 2.0 2.1 1.0 2.1 3.6 0.7 12.8 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.9 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 5.9 0.4 0.0 1.1 0.6 0.2 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.6 1.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 2.2 8.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 ACTN1 ENSG00000072110 "Actinin alpha 1" P12814 14 68874128-68979440 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "smooth muscle: 524.5" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 351.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 364.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004303, HPA006035" Approved Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA 210000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane, Actin filaments, Focal adhesion sites" "CAB004303: AB_626633, HPA006035: AB_1078095" "unprognostic (4.40e-2)" "unprognostic (1.03e-3)" "unprognostic (2.49e-2)" "unprognostic (1.96e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.49e-4)" "unprognostic (6.19e-3)" "prognostic unfavorable (7.63e-5)" "unprognostic (3.62e-1)" "unprognostic (3.23e-2)" "unprognostic (3.16e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (9.08e-10)" "unprognostic (2.87e-2)" "unprognostic (2.00e-1)" "unprognostic (6.05e-3)" "prognostic unfavorable (8.00e-4)" 117.4 40.7 27.3 149.5 55.8 149.3 103.5 0.1 32.0 118.4 20.1 449.8 49.8 313.1 60.3 154.4 152.1 143.9 121.4 29.7 14.7 46.7 61.8 100.0 47.5 24.5 11.0 61.8 46.8 9.1 27.3 96.1 7.3 174.3 109.0 28.2 116.4 295.1 21.7 59.3 106.9 524.5 4.2 55.9 171.7 21.2 32.9 32.6 35.0 13.3 50.7 305.9 83.3 28.8 871.9 262.3 158.6 121.4 275.2 180.5 592.4 749.3 712.0 770.0 571.1 211.8 196.6 0.7 256.5 744.7 310.4 370.9 126.8 790.3 965.2 4.6 38.5 118.2 133.5 179.0 494.0 85.4 14.3 231.7 152.1 479.8 540.3 551.6 428.6 48.2 56.9 1.4 612.0 246.9 10.1 181.1 124.7 217.9 198.1 59.3 294.1 32.6 292.0 225.6 57.0 68.7 649.9 96.8 177.1 474.8 146.0 170.9 546.0 1085.2 432.8 126.9 662.5 113.8 47.8 3.9 314.4 115.7 584.4 64.6 67.5 137.1 5.7 28.8 7.1 0.1 22.7 12.4 45.5 0.2 103.9 92.2 364.2 4.5 8.9 2.0 9.6 89.2 27.3 55.8 0.1 32.0 29.7 14.7 24.5 11.0 7.3 4.2 32.9 28.8 44.7 38.5 25.1 19.6 4.0 119.3 154.9 137.4 82.0 74.7 88.6 157.6 60.3 51.5 36.0 42.3 246.0 155.3 3.0 17.2 3.9 186.8 34.0 65.8 112.8 135.5 38.5 21.9 102.7 144.9 351.8 88.9 34.1 90.2 7.6 15.9 129.5 96.6 79.5 18.5 29.7 57.3 59.0 100.9 82.1 10.7 35.8 96.4 30.2 34.7 105.1 6.0 4.1 9.0 4.3 203.7 28.0 245.6 0.6 132.6 2.4 15.3 47.8 80.8 177.5 30.0 270.6 19.4 18.4 51.8 59.8 66.9 22.7 20.9 47.0 67.1 ACTR10 "ACTR11, Arp10, Arp11, HARP11" ENSG00000131966 "Actin related protein 10" Q9NZ32 14 58200080-58235636 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000699 Approved "Vesicles,Plasma membrane,Focal adhesion sites" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 35: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Vesicles, Plasma membrane, Focal adhesion sites" "HPA000699: " "prognostic unfavorable (3.24e-4)" "unprognostic (4.61e-2)" "unprognostic (6.22e-3)" "unprognostic (2.03e-2)" "unprognostic (4.42e-1)" "unprognostic (1.36e-2)" "prognostic unfavorable (2.71e-5)" "unprognostic (3.20e-1)" "unprognostic (9.30e-2)" "unprognostic (1.53e-1)" "unprognostic (4.86e-1)" "unprognostic (2.36e-1)" "prognostic favorable (8.48e-8)" "unprognostic (1.01e-2)" "unprognostic (2.39e-1)" "unprognostic (2.43e-2)" "unprognostic (8.48e-2)" 12.6 18.0 22.4 3.1 22.4 5.4 12.5 23.4 41.5 15.9 24.5 13.5 2.7 10.2 5.0 16.4 12.7 4.2 22.9 22.2 22.9 18.0 18.5 10.8 4.2 22.3 22.4 15.8 17.4 8.7 20.3 6.4 22.5 14.5 4.4 5.5 10.3 4.7 10.2 13.2 11.3 6.1 22.1 14.7 13.2 10.8 23.0 5.3 13.6 4.1 4.3 12.0 13.9 22.9 4.1 2.6 4.6 1.8 15.3 7.3 2.3 3.1 3.6 4.9 6.1 3.5 4.8 6.3 4.5 6.7 3.0 4.2 6.2 4.5 7.2 3.3 15.3 2.4 4.6 6.9 13.0 4.3 3.4 9.7 6.8 4.5 8.5 4.3 6.7 3.6 2.1 5.0 10.3 11.3 5.7 16.2 2.3 4.0 20.8 4.0 8.0 3.7 9.1 5.2 2.6 2.9 5.9 4.9 16.9 5.2 8.4 7.1 5.4 5.3 11.3 4.9 2.8 2.9 2.0 7.1 5.8 3.3 3.2 15.7 5.4 8.6 6.2 7.3 9.2 6.1 7.0 6.2 4.3 4.1 7.2 7.5 7.8 5.9 8.5 4.8 5.5 4.0 22.4 22.4 23.4 41.5 22.2 22.9 22.3 22.4 22.5 22.1 23.0 22.9 68.3 60.9 44.2 28.7 39.9 53.3 66.4 125.7 34.1 71.4 35.8 43.3 77.0 42.9 75.1 51.5 29.2 110.1 46.4 59.6 125.2 81.2 8.7 40.3 46.7 54.4 33.6 60.0 48.6 59.6 76.9 73.4 32.1 29.7 43.7 49.6 47.8 31.8 77.8 57.2 47.3 48.1 105.8 32.0 38.4 11.6 88.3 47.2 74.7 23.4 52.8 101.4 35.0 40.2 54.6 75.0 29.1 80.1 34.7 59.1 56.3 111.7 67.7 72.0 78.9 54.5 96.6 116.4 60.4 45.7 64.4 156.0 46.1 81.3 41.3 54.6 AFAP1 "AFAP, AFAP-110" ENSG00000196526 "Actin filament associated protein 1" Q8N556 4 7758714-7939926 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Early spermatids: 170.5;Extravillous trophoblasts: 116.3;Inhibitory neurons: 117.2;Late spermatids: 373.8;Oligodendrocyte precursor cells: 125.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 2.9" "Group enriched" "Detected in many" 5 "granulocytes: 2.9;T-cells: 1.2" "Cell line enhanced" "Detected in many" "TIME: 126.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015642, CAB024712" Enhanced Supported "Actin filaments,Focal adhesion sites,Cytosol" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Actin filaments, Cytosol" "Focal adhesion sites" "CAB024712: , HPA015642: AB_1844632" "unprognostic (1.12e-1)" "unprognostic (2.78e-2)" "unprognostic (3.97e-1)" "unprognostic (7.29e-2)" "unprognostic (2.02e-1)" "unprognostic (1.93e-1)" "unprognostic (3.30e-1)" "prognostic unfavorable (2.84e-4)" "unprognostic (2.00e-1)" "unprognostic (3.39e-2)" "unprognostic (3.40e-2)" "unprognostic (1.38e-1)" "prognostic unfavorable (8.18e-4)" "unprognostic (1.40e-2)" "unprognostic (1.56e-1)" "unprognostic (1.85e-1)" "unprognostic (2.44e-2)" 12.6 3.1 7.0 8.7 5.8 0.7 9.7 4.5 6.9 8.7 2.9 17.6 5.6 15.4 2.0 11.0 8.5 9.4 10.8 5.8 4.5 4.9 1.2 8.5 4.4 3.7 2.7 7.1 3.8 14.7 7.9 12.6 2.8 7.7 9.8 3.4 8.6 10.2 3.5 5.3 7.7 15.4 3.4 4.0 6.7 22.0 3.5 3.1 7.4 2.4 4.8 14.2 8.3 3.5 31.9 23.2 16.2 12.9 15.4 27.8 21.3 46.4 68.1 43.6 40.0 7.4 7.2 0.1 15.2 75.5 72.3 15.1 8.6 18.7 28.6 0.9 5.7 0.0 33.2 4.5 43.0 0.0 0.4 17.2 13.8 54.4 35.5 72.2 53.0 4.8 0.7 6.8 23.0 10.3 0.6 0.0 7.0 13.2 44.3 0.0 12.1 1.5 4.7 4.1 31.8 53.0 15.9 10.9 12.4 21.4 4.1 0.3 126.7 53.0 11.8 69.6 23.0 0.0 0.2 0.0 18.9 0.1 61.9 0.0 0.4 2.9 0.4 0.1 0.5 0.0 0.6 0.6 0.0 0.0 1.2 0.5 1.0 0.0 0.0 0.0 0.5 0.7 7.0 5.8 4.5 6.9 5.8 4.5 3.7 2.7 2.8 3.4 3.5 3.5 22.5 6.4 2.0 4.6 0.2 2.9 9.7 16.2 7.4 1.2 10.2 8.9 5.9 10.0 12.7 11.0 4.2 5.6 2.3 14.8 0.0 19.2 170.5 7.5 17.6 20.1 14.5 0.0 24.7 7.7 116.3 21.1 11.2 8.8 0.0 4.4 14.3 0.0 8.5 0.0 117.2 20.6 0.0 0.3 3.6 373.8 11.1 6.0 1.8 30.9 0.6 10.2 0.0 125.2 5.4 29.9 8.6 12.4 0.6 13.5 6.4 4.2 6.4 0.7 6.6 8.0 13.4 12.5 10.0 6.2 4.3 8.8 7.3 2.6 13.9 9.9 AJM1 "ajm-1, C9orf172" ENSG00000232434 "Apical junction component 1 homolog" C9J069 9 136844415-136848801 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.7;pituitary gland: 19.9" "Cell type enhanced" "Detected in some" "Collecting duct cells: 5.5;dendritic cells: 5.2;Granulosa cells: 4.9;Theca cells: 2.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA021200 Uncertain Approved "Focal adhesion sites,Cytosol" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 6: Brain - Smell perception" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Focal adhesion sites, Cytosol" "HPA021200: AB_10601695" "unprognostic (3.30e-3)" "unprognostic (1.67e-1)" "unprognostic (7.68e-3)" "unprognostic (9.54e-2)" "unprognostic (2.34e-1)" "unprognostic (1.08e-2)" "unprognostic (1.27e-2)" "unprognostic (8.00e-2)" "unprognostic (6.29e-2)" "unprognostic (4.33e-1)" "unprognostic (2.72e-3)" "unprognostic (4.34e-2)" "unprognostic (1.05e-1)" "unprognostic (2.71e-3)" "unprognostic (2.94e-1)" "unprognostic (6.07e-3)" "unprognostic (7.27e-2)" 2.4 3.1 14.7 1.0 15.6 1.2 1.7 26.7 17.0 3.8 0.0 17.4 2.1 4.7 0.2 3.2 4.1 0.4 5.3 18.3 1.8 3.6 4.9 2.2 0.5 6.2 2.9 1.4 7.4 0.8 19.9 0.6 2.8 7.7 0.8 0.8 2.3 1.3 3.1 2.6 5.7 0.5 0.0 5.0 5.9 6.4 3.4 0.3 3.2 0.5 0.3 9.3 3.6 4.7 3.0 2.3 0.3 0.9 0.4 0.3 3.7 2.3 0.4 0.3 0.1 0.8 1.5 1.8 1.9 0.6 0.7 3.2 0.3 0.9 0.0 4.6 1.7 0.4 5.2 0.7 1.2 1.1 3.2 0.7 1.1 0.3 0.2 1.8 0.2 0.8 2.8 1.1 0.5 3.3 0.3 3.6 0.9 2.4 3.0 2.2 0.7 5.9 0.7 0.5 5.6 2.0 1.5 5.8 3.3 0.4 4.6 2.2 2.4 3.8 2.6 1.3 1.4 5.0 3.7 0.6 6.6 3.6 0.9 0.0 0.4 0.0 0.5 0.3 0.1 0.0 0.1 0.2 0.4 0.0 0.0 0.2 0.0 0.0 0.5 1.1 0.0 0.2 14.7 15.6 26.7 17.0 18.3 1.8 6.2 2.9 2.8 0.0 3.4 4.7 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.0 1.4 0.0 0.0 0.0 5.5 0.0 0.6 5.2 0.0 0.0 1.8 0.0 0.8 1.1 0.2 0.0 0.0 0.0 0.5 0.9 0.4 0.0 1.8 1.3 4.9 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 1.4 0.0 0.0 1.4 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.3 1.0 2.3 0.0 0.0 ALKBH6 MGC15677 ENSG00000239382 "AlkB homolog 6" Q3KRA9 19 36009120-36014239 "Cancer-related genes, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA073835, HPA074340" Approved Supported "Nucleoplasm,Focal adhesion sites" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 58: T-cells - T-cell receptor" Nucleoplasm "Focal adhesion sites" "HPA073835: AB_2686637, HPA074340: AB_2686680" "unprognostic (1.90e-3)" "unprognostic (1.82e-1)" "unprognostic (5.16e-3)" "unprognostic (1.12e-2)" "unprognostic (1.24e-1)" "unprognostic (5.86e-5)" "unprognostic (6.21e-2)" "unprognostic (4.53e-2)" "unprognostic (3.95e-1)" "unprognostic (3.56e-2)" "unprognostic (8.78e-4)" "unprognostic (1.77e-2)" "unprognostic (2.31e-5)" "unprognostic (9.34e-2)" "unprognostic (2.15e-1)" "unprognostic (3.82e-1)" "unprognostic (1.05e-3)" 5.4 8.4 9.3 3.1 8.3 3.3 5.3 9.7 12.4 6.6 6.9 9.8 2.9 7.6 2.3 7.6 6.7 2.1 6.8 9.3 12.3 7.2 11.5 5.5 4.3 15.7 10.3 5.6 4.4 4.7 9.9 2.7 15.0 7.6 1.9 2.7 6.1 4.0 6.4 6.3 7.3 3.7 8.3 7.9 7.8 4.5 12.7 4.1 6.6 3.9 3.8 7.9 6.0 10.6 12.5 13.1 4.9 7.2 7.4 4.5 8.2 12.1 8.0 13.9 14.0 5.4 6.4 10.8 18.8 6.7 7.2 4.9 5.1 14.0 7.2 17.2 9.4 6.2 5.1 5.9 8.4 5.4 18.3 6.8 9.9 11.5 3.9 4.8 9.5 16.2 9.9 8.0 7.5 13.1 13.1 7.0 3.8 12.8 8.3 8.4 6.7 7.9 10.3 5.5 5.9 6.0 8.2 9.8 10.8 6.8 7.8 12.1 4.1 7.2 10.5 16.6 12.0 14.9 9.6 7.8 15.5 6.1 7.8 58.5 18.2 47.8 26.2 26.0 20.4 32.9 23.8 25.4 16.0 24.6 20.2 19.3 16.0 28.8 20.7 22.7 34.4 16.0 9.3 8.3 9.7 12.4 9.3 12.3 15.7 10.3 15.0 8.3 12.7 10.6 6.1 3.2 1.7 6.8 16.5 6.8 11.1 4.5 9.1 5.6 8.0 6.5 2.0 10.0 3.3 18.4 0.0 17.7 13.1 9.5 5.9 10.4 7.6 6.8 5.0 5.9 13.1 14.5 8.1 9.2 15.8 8.1 14.3 6.3 0.0 7.1 7.9 12.7 11.0 10.1 7.2 11.9 2.0 5.3 7.7 5.4 11.1 9.1 8.8 3.7 15.2 5.5 23.7 2.0 6.5 13.3 13.6 4.5 12.1 7.1 7.8 11.8 2.3 3.3 6.6 4.1 10.1 3.6 2.4 8.7 5.1 19.0 15.5 6.4 9.5 9.5 ARAP2 "CENTD1, PARX" ENSG00000047365 "ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2" Q8WZ64 4 35948221-36244514 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 39.9;brain: 92.8" "Cell type enhanced" "Detected in many" "Astrocytes: 285.4;Late spermatids: 167.5;Oligodendrocytes: 781.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 13.7;hTCEpi: 12.7;MOLT-4: 12.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035925 Approved Approved "Actin filaments,Focal adhesion sites" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Focal adhesion sites" "Actin filaments" "HPA035925: AB_10672075" "unprognostic (2.97e-2)" "unprognostic (8.62e-2)" "unprognostic (3.43e-3)" "unprognostic (1.04e-1)" "unprognostic (8.86e-2)" "unprognostic (2.72e-3)" "unprognostic (1.09e-1)" "unprognostic (3.78e-3)" "unprognostic (2.04e-1)" "unprognostic (2.45e-2)" "unprognostic (2.72e-3)" "unprognostic (2.96e-1)" "unprognostic (4.48e-2)" "unprognostic (4.54e-2)" "unprognostic (3.43e-2)" "unprognostic (1.57e-1)" "unprognostic (6.72e-2)" 4.5 2.2 28.9 10.0 70.4 39.9 5.1 19.9 39.5 3.5 0.0 5.3 8.9 3.3 3.8 13.1 3.3 9.3 1.5 24.5 21.5 3.7 9.4 13.4 15.7 34.1 38.8 1.5 7.0 5.4 2.9 3.5 32.6 2.2 5.6 1.4 4.6 2.9 0.7 16.1 8.9 4.3 18.3 11.5 6.1 6.2 32.1 24.6 23.2 0.8 11.0 9.9 6.3 92.8 8.6 0.7 0.8 0.3 0.0 0.0 4.2 0.0 0.0 0.0 0.0 4.2 13.7 4.1 3.2 0.4 0.0 3.2 1.3 6.7 0.0 0.0 7.6 0.1 2.9 0.2 1.6 5.5 0.0 0.4 12.7 0.0 2.7 4.9 0.0 11.1 0.2 0.7 0.0 3.6 12.8 4.5 1.0 6.0 2.6 6.5 0.0 4.7 9.3 8.7 7.3 0.0 0.4 2.1 2.7 0.4 5.6 1.6 0.0 2.3 7.5 0.0 1.1 0.0 0.0 8.0 0.9 6.1 1.9 0.0 0.5 0.0 3.8 1.8 3.5 1.8 2.1 2.7 0.3 0.9 0.7 1.9 0.4 6.7 4.7 1.2 1.1 0.6 28.9 70.4 19.9 39.5 24.5 21.5 34.1 38.8 32.6 18.3 32.1 92.8 18.6 153.8 23.3 285.4 46.1 39.1 32.9 13.5 21.6 0.8 11.2 7.0 2.1 17.2 33.2 7.3 0.0 0.2 100.4 15.5 7.9 7.9 123.6 31.4 3.0 15.8 3.0 8.6 140.8 10.0 0.4 9.4 20.4 50.0 9.5 5.9 3.3 4.2 8.7 0.0 29.9 11.3 6.1 33.2 24.9 167.5 2.8 35.1 5.4 40.3 26.7 5.4 95.8 161.4 781.2 21.5 23.3 0.7 43.0 30.0 17.4 5.8 18.0 1.2 0.0 8.1 3.6 4.2 3.0 37.0 67.5 0.8 90.7 0.1 6.9 44.1 ARL14EP "ARF7EP, C11orf46, FLJ38968" ENSG00000152219 "ADP ribosylation factor like GTPase 14 effector protein" Q8N8R7 11 30323104-30338223 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 130.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039634, HPA048127" Approved Supported "Nucleoplasm,Vesicles,Focal adhesion sites,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" "Vesicles, Focal adhesion sites, Cytosol" Nucleoplasm "HPA039634: AB_2676606, HPA048127: AB_2680277" "prognostic favorable (2.50e-5)" "unprognostic (8.93e-2)" "unprognostic (6.19e-3)" "unprognostic (1.34e-1)" "unprognostic (1.67e-1)" "unprognostic (3.09e-1)" "prognostic unfavorable (5.26e-4)" "unprognostic (2.50e-2)" "unprognostic (6.50e-3)" "unprognostic (5.76e-2)" "unprognostic (8.86e-2)" "unprognostic (1.04e-1)" "unprognostic (8.57e-3)" "unprognostic (1.60e-1)" "unprognostic (3.47e-1)" "unprognostic (4.50e-2)" "prognostic favorable (7.49e-4)" 13.9 22.5 13.5 13.2 15.6 8.0 20.0 15.9 17.3 17.0 14.9 11.8 9.5 18.9 23.2 11.6 16.4 13.1 22.9 15.7 14.2 17.4 19.7 10.9 22.5 12.4 13.3 20.5 12.9 26.1 12.0 11.5 12.1 19.7 10.8 15.9 19.1 19.9 20.6 12.6 9.7 14.5 13.9 20.8 15.7 14.6 13.3 15.6 24.7 20.8 21.4 14.5 8.1 13.8 10.8 15.4 16.9 14.8 27.1 29.2 8.5 20.8 26.0 18.4 20.2 8.5 4.1 43.8 13.9 15.0 20.5 17.8 24.8 17.5 25.9 35.2 30.7 13.3 12.0 15.0 42.6 24.0 14.7 30.5 34.7 8.7 32.8 26.7 20.6 17.9 21.4 23.2 32.5 10.4 21.9 19.6 19.6 24.1 21.3 18.8 41.2 18.0 24.7 14.8 19.2 20.4 16.2 21.4 25.8 15.0 22.8 13.4 18.1 20.8 11.2 41.7 20.1 36.0 21.9 28.5 20.0 14.8 20.4 12.7 19.2 6.4 23.3 20.0 55.5 35.9 28.2 25.9 26.3 28.9 25.7 25.0 3.5 52.9 15.5 18.9 20.3 23.1 13.5 15.6 15.9 17.3 15.7 14.2 12.4 13.3 12.1 13.9 13.3 13.8 27.3 28.9 33.6 14.4 39.7 12.4 46.6 35.1 8.0 34.0 19.9 30.4 68.1 24.3 23.8 25.8 14.6 19.1 29.2 5.9 76.3 27.3 130.1 25.8 41.0 29.2 14.5 13.2 31.1 22.5 12.7 33.4 12.8 19.0 27.8 33.5 15.4 29.8 25.7 32.0 26.4 11.7 32.6 27.1 29.3 66.3 27.4 28.4 26.6 18.7 45.4 36.1 38.1 27.6 19.9 21.9 8.4 25.2 25.4 46.0 9.4 42.1 27.5 32.4 13.1 33.1 29.8 111.4 37.6 13.8 11.1 11.1 29.6 33.0 12.6 28.4 ARL2 ARFL2 ENSG00000213465 "ADP ribosylation factor like GTPase 2" P36404 11 65014160-65022184 "FDA approved drug targets, Predicted intracellular proteins" "Cell cycle" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 430.8;Late spermatids: 1125.1;Proximal tubular cells: 505.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044610 Supported Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Focal adhesion sites,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "Nucleoli, Golgi apparatus, Focal adhesion sites, Cytosol" "HPA044610: AB_10964207" "unprognostic (9.23e-2)" "unprognostic (3.66e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (4.58e-4)" "unprognostic (1.61e-1)" "unprognostic (5.08e-2)" "unprognostic (1.07e-3)" "unprognostic (2.34e-1)" "unprognostic (9.85e-3)" "unprognostic (6.43e-2)" "unprognostic (6.87e-3)" "prognostic favorable (7.70e-4)" "unprognostic (2.15e-2)" "unprognostic (1.85e-1)" "unprognostic (1.60e-1)" "unprognostic (4.39e-1)" "unprognostic (1.24e-2)" 124.8 93.7 161.5 40.6 190.2 51.3 112.0 172.4 200.2 106.3 132.3 123.1 52.7 121.2 28.2 67.2 94.6 48.0 169.1 157.0 168.7 138.5 22.5 90.4 37.7 171.5 167.9 95.7 75.3 65.3 68.5 56.1 167.2 84.7 32.9 43.5 67.9 66.6 214.2 95.8 73.4 60.9 171.4 63.4 85.2 116.1 167.4 33.5 85.7 158.1 29.0 112.2 93.5 184.4 162.0 257.0 76.5 115.8 207.4 156.5 70.5 82.5 181.7 111.2 109.1 72.8 110.0 62.1 144.5 112.7 168.1 101.4 82.9 140.0 53.1 65.5 130.6 61.9 109.2 111.9 157.8 77.9 54.9 123.7 114.6 92.6 204.4 160.5 150.4 74.0 152.8 110.1 76.4 194.1 63.1 174.5 120.3 77.7 208.6 33.4 81.6 152.9 120.9 70.6 143.3 79.3 66.4 67.6 225.8 74.4 72.3 94.3 109.2 205.9 68.6 164.7 82.1 37.9 57.6 38.5 97.2 112.5 171.3 46.5 78.2 72.5 120.4 80.2 130.9 163.1 110.0 116.9 101.7 149.0 123.5 137.2 10.2 83.3 48.2 140.1 79.0 136.9 161.5 190.2 172.4 200.2 157.0 168.7 171.5 167.9 167.2 171.4 167.4 184.4 179.1 22.4 43.6 0.0 42.7 81.4 94.4 118.4 63.7 70.2 66.8 83.9 103.2 51.5 66.4 82.8 29.2 179.7 40.0 110.0 268.0 142.0 430.8 42.2 59.0 148.0 83.3 69.4 0.0 76.0 193.5 107.0 29.6 50.7 95.7 71.5 137.4 19.7 98.3 69.0 0.0 68.4 83.4 49.7 73.5 1125.1 71.7 49.5 177.9 0.0 100.6 208.4 55.6 0.0 0.0 68.3 115.7 71.1 16.5 79.9 162.4 505.5 47.0 48.9 65.7 74.2 109.7 126.5 79.4 56.3 82.8 107.3 40.0 65.7 98.0 75.9 ARMC5 FLJ13063 ENSG00000140691 "Armadillo repeat containing 5" Q96C12 16 31458080-31467166 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cushing syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatocytes: 28.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 59.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041524, HPA063706" Approved Approved "Nucleoplasm,Focal adhesion sites,Cytosol" "Intracellular and membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 24: NB-4 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Cytosol" "Focal adhesion sites" "HPA041524: AB_10796676, HPA063706: AB_2685098" "unprognostic (1.37e-1)" "unprognostic (1.68e-3)" "unprognostic (8.22e-3)" "unprognostic (9.96e-2)" "unprognostic (2.59e-1)" "unprognostic (2.94e-3)" "unprognostic (4.09e-2)" "unprognostic (6.14e-3)" "unprognostic (2.37e-1)" "unprognostic (1.11e-1)" "prognostic favorable (1.97e-6)" "unprognostic (4.70e-2)" "unprognostic (3.60e-2)" "unprognostic (1.99e-2)" "unprognostic (2.34e-2)" "unprognostic (1.57e-1)" "unprognostic (1.45e-1)" 6.3 7.9 9.0 3.4 9.2 21.4 4.3 8.9 11.7 6.0 7.0 5.8 4.6 6.9 0.9 9.9 5.6 2.0 6.5 9.2 8.1 8.7 24.6 4.6 3.2 12.3 9.4 6.8 6.4 3.0 9.0 2.1 12.4 7.7 0.9 2.4 5.3 2.2 16.0 8.5 7.0 1.7 9.1 8.8 6.8 6.8 9.2 2.9 9.7 3.9 1.3 5.6 6.6 10.5 5.0 7.6 3.3 4.8 2.0 1.5 8.4 6.5 2.8 3.6 3.0 7.2 5.0 4.9 13.3 3.5 3.6 7.5 3.9 5.7 0.7 6.8 9.9 2.2 12.4 16.7 4.0 14.9 14.3 3.7 6.3 3.6 1.0 4.2 5.5 8.0 11.2 11.5 2.5 12.2 5.6 59.5 5.3 2.2 5.0 10.0 4.7 18.2 2.9 5.6 10.7 9.4 5.9 7.8 4.6 2.0 5.1 17.6 10.9 7.8 5.7 3.2 5.4 10.4 9.8 3.0 5.1 12.2 5.7 2.9 2.3 0.7 3.2 1.1 2.7 2.7 2.5 2.6 3.0 2.2 2.2 2.6 1.3 7.1 1.3 7.2 3.2 2.6 9.0 9.2 8.9 11.7 9.2 8.1 12.3 9.4 12.4 9.1 9.2 10.5 8.7 6.4 14.3 4.2 6.2 6.5 9.2 8.7 9.1 6.0 6.3 5.0 5.8 11.5 8.2 0.0 6.2 7.5 7.6 11.1 3.9 5.0 1.2 5.2 8.6 10.8 7.8 8.2 4.3 4.4 5.4 6.1 6.6 7.6 9.5 6.7 8.9 28.7 6.1 13.5 4.0 8.7 6.1 3.7 4.0 0.6 4.4 6.7 1.8 2.8 3.9 7.2 6.2 2.0 4.6 4.4 3.8 5.7 8.0 6.9 9.2 4.6 3.4 5.9 0.0 8.7 6.6 5.5 8.0 9.6 6.3 11.5 7.6 6.1 7.7 6.1 ASAH2 ENSG00000188611 "N-acylsphingosine amidohydrolase 2" Q9NR71 10 50182778-50279720 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Lipid metabolism, Sphingolipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "intestine: 81.5" "Cell type enhanced" "Detected in some" "Late spermatids: 12.5;Muller glia cells: 9.0;Proximal enterocytes: 17.1;Sertoli cells: 6.6" "Low cancer specificity" "Detected in single" "Region enhanced" "Detected in many" "cerebellum: 8.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA061171 Supported Approved "Focal adhesion sites" "Intracellular and membrane" NA NA 2200000 "Cluster 32: T-cells - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 45: Enterocytes - Digestion" "Focal adhesion sites" "HPA061171: AB_2684442" "unprognostic (3.59e-2)" "unprognostic (3.63e-2)" "unprognostic (1.66e-1)" "unprognostic (3.84e-2)" "unprognostic (3.66e-1)" "unprognostic (4.48e-2)" "unprognostic (2.25e-2)" "unprognostic (1.08e-1)" "unprognostic (1.65e-2)" "unprognostic (4.33e-2)" "unprognostic (2.17e-1)" "unprognostic (1.14e-1)" "unprognostic (8.29e-2)" "unprognostic (1.86e-2)" "unprognostic (5.64e-2)" "unprognostic (3.22e-1)" "unprognostic (1.02e-3)" 0.4 0.8 0.0 0.2 1.1 0.0 0.5 8.1 0.4 0.7 0.1 0.8 81.5 0.8 0.5 0.7 0.8 0.3 0.8 0.1 0.4 0.5 2.9 0.6 0.3 3.2 2.9 0.8 1.4 0.6 0.6 0.6 2.2 0.4 0.4 7.3 0.6 0.2 0.8 0.7 64.6 1.2 1.5 0.2 5.0 0.8 0.6 0.5 0.7 0.4 0.1 0.5 0.4 0.6 1.2 0.9 1.0 1.4 1.8 0.7 1.3 1.2 0.9 2.5 2.2 0.7 3.0 0.0 1.4 1.9 2.0 1.1 1.4 0.4 3.0 1.6 2.5 0.9 2.2 1.9 1.1 0.3 0.1 0.2 1.7 4.3 4.8 0.3 0.5 0.0 1.7 0.8 1.7 1.1 1.0 0.0 3.2 0.0 2.7 0.0 4.2 1.1 1.3 0.2 1.8 4.8 1.7 1.2 2.1 2.4 1.0 0.7 1.4 1.2 2.8 3.2 4.0 1.2 0.1 0.0 3.5 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.0 0.3 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.2 0.1 0.0 0.0 1.1 8.1 0.4 0.1 0.4 3.2 2.9 2.2 1.5 0.6 0.6 0.1 0.0 0.0 0.7 0.0 0.4 0.3 0.4 0.0 2.8 0.4 0.3 3.8 0.0 0.9 0.0 2.1 0.4 1.4 0.5 0.0 0.9 4.8 0.1 0.2 0.5 0.0 3.2 1.1 1.6 0.3 0.6 0.0 0.2 0.0 0.2 0.4 2.1 0.2 1.7 1.5 1.8 0.0 0.0 0.0 12.5 1.2 0.0 0.0 0.0 0.0 9.0 1.0 0.0 0.2 1.6 0.1 1.5 0.0 0.3 17.1 1.0 0.7 2.1 6.6 0.6 0.9 1.9 0.9 0.0 0.1 0.3 0.5 0.2 1.2 0.2 ASAH2B "ASAH2C, ASAH2L, bA449O16.3, bA98I6.3" ENSG00000204147 "N-acylsphingosine amidohydrolase 2B" P0C7U1 10 50739318-50816495 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "intestine: 17.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "PC-3: 25.8" "Low region specificity" "Detected in many" HPA061171 Supported Approved "Focal adhesion sites" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 56: Bipolar cells - Visual perception" "Focal adhesion sites" "HPA061171: AB_2684442" "unprognostic (6.86e-3)" "unprognostic (1.91e-2)" "unprognostic (7.22e-2)" "unprognostic (1.13e-1)" "unprognostic (8.55e-2)" "unprognostic (1.18e-2)" "unprognostic (5.42e-3)" "unprognostic (5.03e-3)" "unprognostic (2.21e-2)" "unprognostic (1.11e-1)" "unprognostic (3.79e-2)" "unprognostic (1.78e-2)" "unprognostic (2.21e-3)" "unprognostic (2.80e-1)" "unprognostic (1.08e-1)" "unprognostic (1.44e-1)" "unprognostic (1.46e-1)" 1.5 3.7 1.9 1.9 1.8 1.3 2.8 2.0 2.3 2.1 1.7 2.8 17.2 1.6 3.4 2.6 2.6 2.4 5.2 1.9 2.5 4.4 6.4 2.0 1.7 2.4 2.2 3.0 3.5 4.6 3.3 1.0 2.1 3.6 3.2 7.0 2.6 2.4 3.7 1.8 11.1 2.6 1.6 0.9 3.9 3.0 2.6 1.6 3.7 4.0 1.7 1.8 1.7 2.7 2.5 3.7 3.9 6.3 1.4 3.1 3.0 12.9 7.1 7.5 6.1 8.3 7.4 0.1 4.5 3.4 2.4 2.4 4.3 5.4 6.1 4.6 5.4 1.6 10.5 6.4 5.1 2.2 2.3 3.9 5.6 7.1 10.4 2.3 1.7 0.0 8.0 3.0 5.9 6.0 3.7 0.2 5.0 7.6 25.8 0.1 8.9 3.1 4.2 9.7 7.2 14.7 4.1 5.0 4.3 4.0 8.5 1.4 8.0 3.0 14.0 6.3 16.2 3.9 0.5 0.0 15.5 0.0 5.7 0.3 0.0 0.0 1.1 0.0 3.2 0.4 1.9 1.3 0.0 0.7 2.6 2.5 0.2 0.3 0.0 1.8 2.4 0.8 1.9 1.8 2.0 2.3 1.9 2.5 2.4 2.2 2.1 1.6 2.6 2.7 0.6 3.2 1.1 1.0 1.1 1.7 1.0 1.5 3.4 7.0 2.9 1.7 5.1 5.7 2.1 5.5 8.4 1.7 0.6 1.4 5.9 4.4 0.2 1.6 1.4 1.3 6.7 0.8 6.4 4.8 1.5 2.0 3.6 1.0 0.0 2.3 1.8 7.3 0.3 0.0 6.4 4.2 2.0 0.0 0.0 1.0 1.8 0.1 1.8 2.8 0.2 4.1 2.1 7.1 0.5 4.4 2.5 1.2 2.2 1.3 3.5 6.0 2.0 4.6 0.0 1.0 2.4 4.3 3.0 3.4 0.4 0.5 2.2 2.3 3.9 1.0 ASB16 FLJ30165 ENSG00000161664 "Ankyrin repeat and SOCS box containing 16" Q96NS5 17 44170447-44179084 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skeletal muscle: 67.7" "Cell type enhanced" "Detected in some" "Excitatory neurons: 1.4;Horizontal cells: 1.7;Inhibitory neurons: 1.6;NK-cells: 2.1;Oligodendrocyte precursor cells: 1.5;Rod photoreceptor cells: 2.0" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 5 "cerebellum: 9.8" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-266/70: 11.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA066834 Approved Approved "Focal adhesion sites" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 37: Myocytes - Muscle contraction" "Focal adhesion sites" "HPA066834: AB_2685732" "unprognostic (2.72e-2)" "unprognostic (8.47e-3)" "unprognostic (4.24e-2)" "unprognostic (1.46e-1)" "unprognostic (1.12e-1)" "unprognostic (5.95e-2)" "unprognostic (2.45e-2)" "unprognostic (2.31e-3)" "unprognostic (1.03e-2)" "unprognostic (6.13e-2)" "unprognostic (7.23e-4)" "unprognostic (5.84e-2)" "unprognostic (3.97e-2)" "unprognostic (8.53e-3)" "unprognostic (7.33e-2)" "unprognostic (2.20e-1)" "unprognostic (1.07e-3)" 0.8 1.0 0.8 2.3 0.9 2.2 0.6 9.8 1.2 1.1 0.0 1.5 2.1 1.9 0.0 1.0 1.4 1.1 4.6 0.5 0.3 1.1 0.6 1.1 3.3 1.5 1.8 1.7 3.6 1.6 1.9 0.6 1.6 1.6 0.0 2.3 2.0 0.2 67.7 3.2 2.1 0.6 0.1 3.1 2.0 1.0 1.1 0.0 1.2 13.1 0.0 1.2 0.8 1.6 2.1 3.9 4.6 4.2 0.0 0.0 3.7 4.2 0.0 0.0 0.0 3.0 2.3 3.2 2.5 0.0 1.0 4.9 0.0 0.0 0.0 5.0 6.8 2.0 8.0 3.4 0.0 2.1 6.2 0.0 0.0 0.0 0.0 1.2 0.0 4.7 3.7 7.6 0.0 3.5 2.6 4.0 1.3 0.7 4.5 8.0 4.4 4.8 0.0 3.1 4.6 2.6 2.0 0.6 0.7 1.3 6.0 2.0 2.1 5.7 5.1 3.5 2.7 11.8 6.2 2.9 1.3 3.0 3.8 2.3 1.3 5.8 1.7 1.2 2.0 2.5 1.8 1.6 0.7 1.9 2.3 1.5 4.1 2.6 1.1 1.6 1.9 1.6 0.8 0.9 9.8 1.2 0.5 0.3 1.5 1.8 1.6 0.1 1.1 1.6 0.0 0.0 0.0 0.3 0.5 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.0 1.4 0.2 0.1 0.1 0.0 0.2 0.0 0.2 0.7 0.0 0.1 1.7 1.6 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 1.0 0.0 0.7 2.1 1.5 1.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.0 0.0 0.6 0.2 0.3 0.4 0.3 0.0 0.0 0.2 0.3 0.1 0.1 ASCC2 "ASC1p100, DKFZp586O0223, FLJ21588" ENSG00000100325 "Activating signal cointegrator 1 complex subunit 2" Q9H1I8 22 29788609-29838304 "Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 155.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001439, HPA052879" Approved Approved "Nucleoplasm,Focal adhesion sites,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 3: HMC-1 - Innate immune response" "Cluster 34: Spermatids - Unknown function" "Focal adhesion sites, Cytosol" Nucleoplasm "HPA001439: AB_1078229, HPA052879: AB_2732577" "unprognostic (1.70e-1)" "unprognostic (1.02e-2)" "unprognostic (8.58e-2)" "unprognostic (3.83e-3)" "unprognostic (1.84e-1)" "unprognostic (2.45e-3)" "unprognostic (3.01e-3)" "unprognostic (1.16e-1)" "unprognostic (1.35e-1)" "unprognostic (5.39e-2)" "unprognostic (1.56e-2)" "unprognostic (1.24e-1)" "unprognostic (3.97e-3)" "unprognostic (5.19e-2)" "unprognostic (7.53e-2)" "unprognostic (3.81e-1)" "unprognostic (2.05e-3)" 26.6 31.3 11.4 22.7 12.7 53.7 24.9 12.6 13.7 23.7 16.7 24.5 23.7 21.0 16.1 42.0 19.9 17.1 22.8 11.6 11.9 19.8 35.8 22.1 24.5 13.5 12.9 19.9 23.5 21.8 26.7 21.8 13.2 27.1 24.6 8.4 29.8 18.0 43.5 30.1 23.1 19.2 12.9 29.4 37.0 24.5 12.5 29.6 28.3 32.3 34.0 26.8 27.5 13.3 46.9 26.8 28.4 38.7 41.6 36.7 40.7 47.6 36.3 48.4 48.1 31.5 24.7 46.5 33.4 46.2 30.7 55.5 36.8 54.0 40.5 59.8 64.3 39.9 33.0 38.0 52.1 72.3 115.6 39.6 48.2 55.0 50.0 28.4 42.9 30.7 41.8 43.7 44.3 57.8 44.5 37.9 20.7 65.6 36.0 53.0 34.9 48.6 29.6 76.1 43.8 38.5 44.3 48.2 35.4 28.8 34.3 37.4 42.8 67.1 11.3 41.2 47.9 51.9 42.8 54.4 39.2 39.9 49.5 44.7 29.8 53.6 32.1 49.2 28.4 18.8 23.6 26.9 37.7 15.0 24.1 24.6 9.2 33.7 43.9 21.7 30.3 20.0 11.4 12.7 12.6 13.7 11.6 11.9 13.5 12.9 13.2 12.9 12.5 13.3 27.7 19.2 14.7 18.6 35.8 30.0 25.2 38.1 13.1 9.4 23.3 12.3 19.1 31.5 33.3 40.5 4.2 46.3 40.5 38.8 11.7 25.4 110.2 14.0 28.1 20.7 15.5 116.0 13.5 24.9 63.3 22.9 69.8 20.0 34.9 24.3 22.9 25.7 30.6 5.0 13.8 23.2 44.7 29.2 37.3 155.2 31.1 29.1 28.4 11.2 27.9 12.2 56.7 15.6 16.3 27.7 34.0 24.8 32.4 16.2 46.8 18.2 24.4 13.6 19.7 19.6 19.7 48.4 22.5 35.0 39.2 44.3 34.9 27.8 23.9 34.2 ATP2C2 "KIAA0703, SPCA2" ENSG00000064270 "ATPase secretory pathway Ca2+ transporting 2" O75185 16 84368527-84464187 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" Translocase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 37.4;skin 1: 26.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 56.2;Club cells: 50.0;Intestinal goblet cells: 82.3;Oligodendrocyte precursor cells: 58.8;Respiratory ciliated cells: 78.2;Undifferentiated cells: 77.1" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 24.5;OE19: 44.4;RT4: 19.3;SK-BR-3: 33.0;T-47d: 11.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA052262, HPA075812" Approved Approved "Plasma membrane,Focal adhesion sites" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Focal adhesion sites" "HPA052262: AB_2681776, HPA075812: AB_2686765" "unprognostic (2.28e-2)" "unprognostic (6.13e-2)" "unprognostic (3.34e-2)" "prognostic favorable (6.20e-6)" "unprognostic (2.04e-1)" "unprognostic (2.41e-2)" "unprognostic (8.36e-2)" "unprognostic (1.72e-1)" "unprognostic (9.92e-2)" "unprognostic (1.89e-2)" "unprognostic (5.08e-2)" "unprognostic (2.16e-1)" "unprognostic (8.37e-3)" "unprognostic (1.17e-1)" "unprognostic (1.02e-1)" "unprognostic (4.32e-4)" "unprognostic (1.39e-1)" 0.0 0.0 1.4 2.4 1.4 11.0 2.5 0.5 1.3 6.4 0.5 30.1 27.3 1.0 0.1 4.7 6.8 4.6 0.0 1.3 1.1 1.8 0.1 10.5 0.0 1.0 0.9 0.0 0.7 3.3 1.0 0.9 1.0 12.5 37.4 0.9 19.6 0.2 0.1 26.0 20.3 0.6 0.6 0.4 5.9 0.4 1.1 0.0 8.9 0.0 0.5 4.0 4.6 0.8 6.2 0.4 0.9 0.1 0.0 0.0 6.4 0.2 0.0 0.0 0.0 5.8 5.2 0.0 0.1 0.0 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 24.5 0.0 0.0 0.0 44.4 0.1 0.0 0.0 0.2 0.0 19.3 4.9 0.0 0.0 33.0 0.2 0.9 11.1 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.4 1.4 0.5 1.3 1.3 1.1 1.0 0.9 1.0 0.6 1.1 0.8 0.0 32.1 56.2 4.2 0.0 0.6 14.3 39.9 0.6 1.3 20.8 3.2 0.8 5.7 50.0 0.0 0.0 2.0 0.1 44.4 0.0 9.0 3.2 26.8 2.5 0.7 34.2 0.0 8.3 2.5 2.4 0.5 22.4 28.0 8.9 0.0 0.0 0.1 0.3 0.0 1.8 82.3 8.2 0.0 1.2 1.9 0.0 0.6 1.8 1.0 0.0 1.9 0.0 58.8 2.4 4.7 29.2 0.0 0.0 13.8 10.2 1.8 78.2 5.2 0.0 0.1 1.8 0.8 1.0 1.5 1.1 24.1 0.9 0.2 77.1 9.9 ATP6V0A2 "a2, ATP6a2, ATP6N1D, J6B7, Stv1, TJ6, TJ6M, TJ6s, Vph1" ENSG00000185344 "ATPase H+ transporting V0 subunit a2" Q9Y487 12 123712353-123761755 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 75.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 13.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 51.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044279 Approved Supported "Vesicles,Plasma membrane,Focal adhesion sites" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Plasma membrane" "Vesicles, Focal adhesion sites" "HPA044279: AB_10961274" "unprognostic (2.60e-1)" "unprognostic (8.79e-3)" "unprognostic (3.60e-2)" "unprognostic (1.50e-1)" "unprognostic (2.70e-1)" "unprognostic (2.29e-2)" "unprognostic (2.06e-4)" "unprognostic (1.40e-1)" "unprognostic (3.77e-2)" "unprognostic (1.75e-1)" "unprognostic (8.85e-3)" "unprognostic (1.63e-1)" "unprognostic (1.26e-1)" "unprognostic (7.48e-2)" "unprognostic (1.12e-1)" "unprognostic (3.47e-1)" "unprognostic (1.58e-1)" 6.6 4.4 5.6 7.0 6.2 10.4 5.7 7.4 6.5 4.7 6.9 5.5 8.7 6.0 3.9 4.3 4.8 3.8 4.7 6.0 6.0 3.8 4.2 6.3 8.3 6.6 5.8 4.1 5.7 3.7 4.9 3.7 6.5 4.7 5.8 6.7 7.6 4.0 6.5 9.4 7.0 5.1 5.6 6.6 8.8 4.9 6.2 7.5 4.8 3.5 8.2 5.3 4.5 7.9 4.8 10.3 12.0 17.8 9.2 7.0 6.7 6.2 6.2 5.4 5.8 6.9 2.7 18.0 4.2 7.6 5.5 9.0 16.1 6.2 4.5 11.4 10.2 27.9 9.2 5.4 10.2 16.8 51.0 6.7 4.4 5.9 7.4 9.0 5.0 15.0 14.5 3.4 8.1 8.4 15.4 24.8 11.5 6.6 6.5 15.7 9.9 6.4 8.3 10.4 7.2 13.6 9.3 6.9 9.4 6.6 5.9 14.4 8.3 8.0 3.1 10.8 9.1 10.8 12.8 14.9 9.4 12.1 6.5 6.3 0.7 13.7 1.7 0.9 1.0 0.9 1.7 1.5 0.8 3.7 1.6 1.8 2.0 1.7 1.5 2.8 1.0 0.8 5.6 6.2 7.4 6.5 6.0 6.0 6.6 5.8 6.5 5.6 6.2 7.9 13.0 6.4 11.0 3.9 20.4 10.1 10.8 4.6 11.4 20.5 7.9 5.3 8.8 12.8 8.3 9.2 12.5 5.2 27.9 17.9 0.0 8.1 10.2 11.0 11.9 10.6 13.2 50.3 21.2 10.9 5.7 11.3 18.3 12.3 75.3 8.7 18.2 11.4 8.4 11.8 19.3 9.8 2.0 9.4 17.2 4.5 8.7 11.3 1.8 7.5 13.2 9.0 25.7 10.6 17.1 9.2 9.0 9.4 19.7 15.7 11.1 4.0 13.5 28.8 6.6 12.4 10.9 23.6 12.6 9.6 14.2 6.8 21.8 5.7 11.4 11.4 BTBD7 "FLJ10648, FUP1" ENSG00000011114 "BTB domain containing 7" Q9P203 14 93237550-93333092 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 175.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049926, HPA053406" Uncertain Approved "Focal adhesion sites" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "Focal adhesion sites" "HPA049926: AB_2680956, HPA053406: AB_2682137" "unprognostic (3.36e-1)" "unprognostic (4.36e-2)" "unprognostic (1.04e-2)" "unprognostic (1.01e-1)" "unprognostic (7.74e-2)" "unprognostic (1.16e-1)" "unprognostic (1.67e-2)" "unprognostic (2.69e-1)" "unprognostic (6.55e-2)" "unprognostic (1.31e-1)" "unprognostic (8.97e-3)" "unprognostic (4.34e-2)" "prognostic favorable (1.69e-6)" "unprognostic (7.27e-2)" "unprognostic (1.97e-1)" "unprognostic (4.72e-2)" "unprognostic (9.52e-2)" 3.9 2.7 1.2 2.2 2.1 5.6 3.4 3.6 1.8 3.4 0.0 3.3 1.8 3.5 1.5 4.5 3.4 2.0 3.1 1.2 2.7 3.9 2.9 3.8 1.2 3.0 3.1 3.5 3.4 4.0 1.9 2.6 2.6 2.9 2.3 2.5 3.6 1.7 4.7 4.1 3.3 2.1 1.7 2.3 3.0 8.0 3.6 1.2 3.5 1.6 1.4 3.5 3.9 4.1 6.6 4.0 5.2 1.8 2.9 2.5 9.0 6.0 3.8 5.0 3.0 4.5 4.9 4.3 4.9 6.5 3.6 6.1 4.6 10.4 7.7 5.1 3.5 2.9 2.5 3.3 1.7 7.6 3.6 3.6 2.0 5.1 7.3 3.8 7.5 1.7 3.1 3.5 5.2 7.2 2.0 2.9 3.2 3.3 11.2 5.9 7.6 0.9 6.1 15.5 6.7 6.2 7.9 3.0 2.1 5.6 5.3 5.4 8.9 4.2 4.3 3.0 5.3 2.5 3.5 3.9 2.1 2.1 3.0 0.8 0.1 1.3 0.3 0.2 0.1 0.6 0.2 0.3 0.1 0.4 0.1 0.2 0.5 0.1 0.3 0.4 0.4 0.0 1.2 2.1 3.6 1.8 1.2 2.7 3.0 3.1 2.6 1.7 3.6 4.1 53.6 51.3 27.7 76.4 29.0 32.4 29.0 18.1 26.7 27.9 31.9 23.9 20.9 30.0 19.6 55.2 37.5 24.2 31.6 34.5 13.7 32.3 47.9 58.2 55.7 48.5 28.8 23.4 80.2 24.6 22.5 35.6 29.0 75.5 24.7 33.3 51.4 18.6 17.8 26.9 81.6 26.2 14.2 27.7 39.5 45.7 23.6 36.1 10.6 99.3 39.5 23.9 26.8 89.0 175.7 45.2 22.0 39.5 36.0 45.8 22.1 39.3 22.9 30.4 13.1 58.3 56.4 23.7 36.6 32.9 36.9 30.6 28.2 33.1 27.7 64.5 C11orf96 AG2 ENSG00000187479 "Chromosome 11 open reading frame 96" Q7Z7L8 11 43925342-43943878 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "fallopian tube: 750.2;ovary: 721.3" "Cell type enhanced" "Detected in many" "Adipocytes: 796.5;Endometrial stromal cells: 906.3;Fibroblasts: 801.3;Granulosa cells: 982.4;Peritubular cells: 474.3;Smooth muscle cells: 1942.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 9 "SH-SY5Y: 197.7" "Low region specificity" "Detected in all" HPA038843 Uncertain Approved "Nucleoplasm,Focal adhesion sites,Cytosol" No NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Focal adhesion sites, Cytosol" "HPA038843: AB_10673296" "unprognostic (1.55e-1)" "unprognostic (1.33e-1)" "unprognostic (1.28e-2)" "unprognostic (8.15e-3)" "unprognostic (5.49e-2)" "unprognostic (3.42e-3)" "unprognostic (8.11e-3)" "unprognostic (1.15e-2)" "unprognostic (2.46e-2)" "unprognostic (1.02e-1)" "unprognostic (3.01e-1)" "unprognostic (5.98e-2)" "prognostic unfavorable (2.34e-5)" "unprognostic (2.65e-2)" "unprognostic (2.07e-1)" "unprognostic (1.18e-2)" "unprognostic (3.19e-2)" 478.3 199.0 28.7 39.2 24.3 4.9 203.5 26.1 34.2 305.0 18.4 151.0 19.7 283.4 8.7 44.8 750.2 61.1 269.3 24.8 44.4 226.8 179.2 377.9 6.8 93.8 42.4 721.3 60.7 3.2 126.5 15.4 38.5 157.3 8.4 1.3 22.2 14.3 110.8 97.2 130.3 28.4 35.1 54.4 240.2 67.8 44.5 5.0 119.4 10.3 0.7 176.3 148.1 21.0 0.0 0.0 0.0 0.0 4.0 2.0 1.1 0.3 1.3 0.0 0.1 0.1 0.0 0.0 0.5 0.5 2.1 0.1 0.4 0.0 0.0 0.0 2.9 6.2 0.1 0.0 0.8 0.5 0.6 0.3 0.1 1.4 0.0 0.0 1.2 2.1 2.3 0.0 0.0 0.0 2.4 2.7 1.7 0.0 0.9 10.3 0.7 4.7 0.0 0.0 2.2 197.7 0.0 0.0 19.4 5.5 0.0 2.3 2.7 9.2 3.8 2.3 0.2 22.5 0.2 3.2 7.1 1.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.7 24.3 26.1 34.2 24.8 44.4 93.8 42.4 38.5 35.1 44.5 21.0 796.5 6.4 139.9 0.0 1.9 92.9 15.2 1.6 5.2 15.4 8.2 13.7 6.0 0.0 1.9 0.0 2.1 1.5 13.7 0.3 0.0 4.5 4.3 34.1 906.3 260.3 0.0 2.7 0.0 0.6 4.4 801.3 4.1 183.3 13.9 982.4 172.7 6.4 3.8 1.7 0.0 0.2 0.0 8.4 171.8 13.9 215.6 27.1 174.3 0.0 0.1 2.7 0.0 0.0 0.0 1.9 0.0 474.3 9.4 73.6 0.0 0.0 0.9 9.3 302.4 173.2 1942.9 2.1 1.5 6.5 88.5 3.1 14.2 243.9 0.1 50.5 C4orf36 MGC26744 ENSG00000163633 "Chromosome 4 open reading frame 36" Q96KX1 4 86876205-86892422 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 10.7" "Group enriched" "Detected in many" 12 "Early spermatids: 129.5;Late spermatids: 349.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 2.8;CAPAN-2: 2.1;hTCEpi: 1.7;hTERT-HME1: 2.4" HPA057434 Uncertain Uncertain "Focal adhesion sites,Cytosol" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 31: Spermatids - Spermatogenesis" "Focal adhesion sites" Cytosol "HPA057434: AB_2683438" "unprognostic (2.01e-1)" "unprognostic (2.68e-1)" "unprognostic (7.78e-2)" "unprognostic (4.76e-2)" "unprognostic (7.31e-2)" "unprognostic (5.68e-2)" "unprognostic (5.93e-3)" "unprognostic (2.39e-2)" "unprognostic (5.20e-2)" "unprognostic (2.77e-1)" "unprognostic (2.76e-2)" "unprognostic (2.55e-1)" "prognostic favorable (7.69e-5)" "unprognostic (2.85e-1)" "unprognostic (2.44e-1)" "unprognostic (4.28e-2)" "unprognostic (7.75e-2)" 0.4 0.1 0.1 0.0 0.1 0.0 0.5 0.0 0.4 1.0 0.0 0.1 0.1 0.3 0.0 0.7 0.2 0.0 0.1 0.1 0.2 0.4 0.1 0.4 0.0 0.1 0.1 0.6 0.2 0.1 0.2 0.0 0.1 0.5 0.0 0.0 0.4 0.1 0.0 1.5 0.1 0.2 0.1 0.1 0.1 10.7 0.1 0.0 0.4 0.0 0.1 0.3 0.6 0.3 2.8 0.2 0.1 0.1 0.0 0.1 0.6 1.4 0.4 0.3 0.0 0.1 2.1 0.0 0.2 0.0 0.0 1.2 0.2 1.2 0.3 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.7 0.0 2.4 0.0 0.0 0.1 0.2 0.0 0.0 1.2 0.8 0.1 0.3 0.5 0.0 0.7 0.0 0.0 0.3 1.1 0.3 0.8 0.3 0.2 0.0 0.2 0.5 0.0 0.0 0.2 0.4 0.1 0.1 0.1 0.4 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.3 0.2 0.0 0.0 2.6 2.3 5.0 8.9 9.6 4.0 5.4 0.2 0.0 19.2 15.7 5.1 0.0 10.4 0.9 4.0 13.0 0.0 0.1 129.5 0.1 0.4 5.9 3.0 4.8 1.4 0.0 2.9 4.3 11.7 0.2 0.0 0.1 7.9 3.1 3.3 1.7 1.6 9.1 8.2 6.2 5.8 349.7 5.3 3.5 1.8 1.0 1.4 6.4 5.2 1.0 3.6 0.2 11.3 3.4 6.9 3.7 10.8 0.0 5.6 6.7 6.6 6.2 2.3 3.9 6.9 6.7 10.2 9.7 2.1 0.0 7.1 4.6 CAPN12 ENSG00000182472 "Calpain 12" Q6ZSI9 19 38730187-38769904 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "gallbladder: 22.8;liver: 24.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 41.4;Cholangiocytes: 41.5;NK-cells: 39.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 9 "basophil: 59.3;NK-cell: 25.5" "Group enriched" "Detected in many" 9 "granulocytes: 59.3;NK-cells: 25.5" "Cell line enriched" "Detected in some" 14 "HMC-1: 35.1" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hippocampal formation: 3.0" HPA053322 Approved "Nucleoplasm,Focal adhesion sites" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Focal adhesion sites" Nucleoplasm "HPA053322: AB_2682111" "unprognostic (1.81e-1)" "unprognostic (4.48e-2)" "unprognostic (1.04e-2)" "unprognostic (1.08e-1)" "unprognostic (1.95e-2)" "unprognostic (2.81e-2)" "unprognostic (1.02e-1)" "unprognostic (6.01e-3)" "unprognostic (7.20e-2)" "unprognostic (2.45e-2)" "unprognostic (1.29e-1)" "unprognostic (4.01e-2)" "prognostic unfavorable (5.90e-6)" "unprognostic (7.04e-2)" "unprognostic (4.01e-2)" "unprognostic (3.00e-1)" "unprognostic (4.59e-2)" 0.5 0.2 0.4 1.3 0.4 0.5 0.6 0.3 0.7 5.3 0.3 1.1 2.6 1.1 0.7 1.0 2.9 22.8 1.1 0.3 0.7 3.5 24.8 2.5 2.2 0.5 0.4 0.3 1.9 0.5 0.3 0.2 0.7 0.4 1.0 0.0 5.3 1.2 0.4 4.0 1.0 0.8 0.3 1.9 2.0 0.5 0.7 1.3 0.3 0.0 2.8 0.5 0.9 0.4 0.2 1.4 0.0 0.0 0.2 0.1 2.0 0.0 0.0 0.0 0.1 2.4 0.1 0.6 0.0 0.0 0.3 1.0 0.0 0.6 0.0 0.1 0.0 0.2 0.7 0.7 0.0 0.0 35.1 0.6 2.0 0.2 0.0 0.0 0.0 0.0 0.4 0.4 0.2 0.2 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.1 1.4 0.0 0.1 0.0 0.1 0.3 0.0 0.3 0.1 1.1 0.0 0.0 0.0 0.0 0.4 0.7 0.6 0.0 0.1 0.0 0.5 59.3 0.1 3.6 4.4 0.0 4.4 2.6 1.3 2.4 0.1 3.8 0.0 1.1 0.7 25.5 0.0 0.0 1.0 1.2 0.4 0.4 0.3 0.7 0.3 0.7 0.5 0.4 0.7 0.3 0.7 0.4 2.5 12.8 41.4 0.7 14.8 9.4 9.2 16.5 4.0 1.6 3.3 4.6 0.9 41.5 8.5 5.5 0.0 1.7 17.7 4.3 0.0 11.6 0.8 7.8 2.8 2.6 3.6 1.3 0.5 7.2 9.4 1.1 8.6 21.2 5.1 0.9 2.5 16.1 1.0 0.0 0.2 21.4 10.2 1.3 3.3 0.6 0.6 1.4 3.6 1.0 1.0 1.4 39.1 0.0 0.3 5.4 6.0 0.4 9.8 5.4 9.7 21.7 10.0 0.6 0.0 2.3 3.0 0.3 2.4 3.4 9.5 2.9 19.1 2.2 15.7 4.8 CHRNA5 ENSG00000169684 "Cholinergic receptor nicotinic alpha 5 subunit" P30532 15 78565520-78595269 "Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 13.0;Extravillous trophoblasts: 11.5;Intestinal goblet cells: 9.8;Spermatocytes: 12.4;Spermatogonia: 28.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA054381 Approved Approved "Plasma membrane,Focal adhesion sites" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Focal adhesion sites" "Plasma membrane" "HPA054381: AB_2682468" "unprognostic (2.66e-1)" "unprognostic (1.76e-1)" "unprognostic (2.32e-2)" "unprognostic (3.20e-3)" "unprognostic (6.66e-2)" "unprognostic (1.29e-3)" "unprognostic (7.03e-5)" "prognostic unfavorable (3.64e-5)" "unprognostic (1.34e-2)" "unprognostic (1.31e-2)" "unprognostic (4.52e-2)" "unprognostic (8.97e-2)" "unprognostic (6.50e-11)" "unprognostic (4.37e-1)" "unprognostic (5.39e-1)" "unprognostic (5.44e-2)" "unprognostic (2.22e-1)" 0.8 2.0 1.9 1.9 1.8 0.5 1.5 2.7 3.0 1.0 2.0 4.0 4.8 1.3 1.1 1.6 0.5 4.4 1.3 1.7 1.8 0.3 0.3 0.5 0.7 1.7 2.2 0.7 1.9 0.3 0.2 1.1 2.4 1.9 4.2 2.5 0.7 0.4 3.9 0.6 2.4 2.1 1.6 0.3 2.8 3.1 2.4 0.7 0.3 0.5 1.1 1.8 1.1 2.7 16.5 41.8 22.4 12.5 2.7 1.9 9.1 12.0 5.8 13.0 23.4 16.1 76.7 9.8 28.6 2.6 34.7 14.3 43.5 17.6 13.2 20.1 51.9 18.3 29.5 16.2 1.4 12.4 24.7 0.7 3.1 3.5 4.7 4.8 24.5 13.6 18.2 12.5 8.3 36.1 15.9 4.3 18.2 32.4 11.5 20.1 25.8 9.9 15.7 39.2 37.7 55.0 28.6 27.5 14.1 12.7 61.2 3.2 5.3 17.6 21.0 13.0 38.0 14.3 63.4 11.3 10.6 19.8 16.5 1.0 0.4 0.7 0.1 0.4 0.1 0.0 0.1 0.1 0.2 0.1 0.3 0.3 0.7 0.3 0.4 0.2 0.0 0.1 1.9 1.8 2.7 3.0 1.7 1.8 1.7 2.2 2.4 1.6 2.4 2.7 0.9 0.0 0.0 0.3 1.4 3.2 13.0 0.5 8.6 7.6 1.2 2.9 1.2 2.8 0.2 0.0 0.0 2.6 0.4 1.2 0.0 0.3 1.2 0.5 0.6 2.0 3.5 0.8 1.0 2.0 11.5 1.0 0.5 0.6 0.0 1.5 0.0 0.3 1.0 5.0 1.1 9.8 0.0 0.0 2.3 2.6 0.3 0.8 1.8 0.0 0.2 0.4 1.0 0.5 0.9 0.7 0.1 0.4 0.9 6.7 0.1 0.4 0.1 0.7 0.0 1.3 1.6 12.4 28.8 2.9 1.6 1.0 2.0 0.2 2.1 3.2 CORO2B "ClipinC, KIAA0925" ENSG00000103647 "Coronin 2B" Q9UQ03 15 68578993-68727806 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 83.4;retina: 45.2" "Cell type enhanced" "Detected in many" "Astrocytes: 57.1;Bipolar cells: 43.2;Cone photoreceptor cells: 37.5;Excitatory neurons: 96.6;Inhibitory neurons: 50.0;Oligodendrocytes: 146.4" "Group enriched" "Detected in many" 8 "glioma: 34.7;melanoma: 21.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.2" "Lineage enriched" "Detected in single" 13 "B-cells: 1.2" "Cell line enhanced" "Detected in many" "ASC diff: 26.8;ASC TERT1: 57.5;HSkMC: 41.6;hTEC/SVTERT24-B: 34.6;U-87 MG: 59.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017960 Enhanced Supported Approved "Plasma membrane,Focal adhesion sites" NA NA "Cluster 37: B-cells - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Focal adhesion sites" "HPA017960: AB_1847167" "unprognostic (1.35e-1)" "unprognostic (2.63e-2)" "unprognostic (2.81e-3)" "unprognostic (4.71e-3)" "unprognostic (3.28e-1)" "unprognostic (8.11e-5)" "unprognostic (4.77e-2)" "unprognostic (1.24e-1)" "unprognostic (3.68e-2)" "unprognostic (1.81e-1)" "unprognostic (1.33e-3)" "unprognostic (4.12e-2)" "unprognostic (1.26e-1)" "unprognostic (1.10e-2)" "unprognostic (5.83e-2)" "unprognostic (3.59e-2)" "unprognostic (1.87e-2)" 10.9 3.5 44.1 2.0 60.9 0.7 7.2 62.1 66.5 7.2 28.2 5.9 1.2 7.5 2.2 1.4 27.5 4.7 16.4 48.1 43.5 9.2 1.3 5.1 1.8 62.4 62.7 14.9 2.2 0.5 3.5 3.2 58.0 4.3 1.5 45.2 2.7 4.9 2.6 4.1 2.8 6.3 51.9 3.9 3.1 1.0 66.5 1.3 6.1 4.5 0.8 4.1 3.7 83.4 0.6 0.8 26.2 2.2 26.8 57.5 0.0 13.7 15.0 2.3 3.2 0.3 3.0 3.5 1.6 2.3 3.7 0.2 1.0 0.3 9.5 0.0 1.2 0.0 0.0 1.2 9.8 0.0 0.4 41.6 0.3 34.6 2.0 20.4 1.0 0.0 0.0 0.1 24.4 0.1 0.0 0.1 6.5 0.0 0.1 2.2 0.1 1.2 3.7 0.0 15.3 0.3 0.2 0.0 7.8 4.8 0.0 3.1 0.2 7.8 8.9 1.7 18.3 0.0 0.0 3.5 59.2 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.1 60.9 62.1 66.5 48.1 43.5 62.4 62.7 58.0 51.9 66.5 83.4 2.8 0.0 0.0 57.1 1.1 1.0 0.4 0.0 0.0 43.2 0.1 1.0 1.5 0.0 0.0 7.3 37.5 0.0 0.0 0.0 0.0 3.8 0.4 2.1 11.6 3.0 3.6 0.0 96.6 0.6 0.0 8.0 0.0 0.3 0.0 0.9 6.4 0.0 0.2 0.0 50.0 0.3 0.0 0.3 0.7 0.7 7.8 0.3 7.2 11.2 0.1 12.5 0.0 17.1 146.4 0.6 0.0 0.4 0.0 0.1 0.0 0.1 8.1 21.4 6.6 1.4 2.1 0.2 0.5 0.1 0.9 0.0 0.1 7.5 0.0 0.1 CPAMD8 "K-CAP, KIAA1283, VIP" ENSG00000160111 "C3 and PZP like alpha-2-macroglobulin domain containing 8" Q8IZJ3 19 16892951-17026815 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.7;prostate: 34.1;seminal vesicle: 36.1" "Cell type enhanced" "Detected in many" "Adipocytes: 19.5;Alveolar cells type 1: 22.4;Alveolar cells type 2: 29.8;Collecting duct cells: 27.6;Leydig cells: 31.4;Prostatic glandular cells: 19.3" "Cancer enhanced" "Detected in many" "thyroid cancer: 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "BEWO: 19.5;EFO-21: 12.6;T-47d: 34.4" "Region enriched" "Detected in single" 8 "spinal cord: 5.6" "HPA031327, HPA031328, HPA031329, HPA031330" Uncertain Uncertain "Focal adhesion sites" "Secreted to blood" NA NA 2700000 "Cluster 21: Non-specific - Transcription" "Cluster 6: T47d - Mammary gland" "Cluster 43: Cardiomyocytes - Nuclear processes" "Focal adhesion sites" "HPA031327: AB_2673829, HPA031328: AB_2673830, HPA031329: , HPA031330: AB_10603788" "unprognostic (4.71e-3)" "unprognostic (1.07e-2)" "unprognostic (4.20e-2)" "unprognostic (2.76e-2)" "unprognostic (4.32e-2)" "unprognostic (4.06e-3)" "unprognostic (7.85e-2)" "unprognostic (9.30e-2)" "unprognostic (1.58e-1)" "unprognostic (2.71e-2)" "unprognostic (1.62e-1)" "unprognostic (4.24e-2)" "unprognostic (8.69e-2)" "unprognostic (1.01e-3)" "unprognostic (2.08e-1)" "unprognostic (8.45e-2)" "unprognostic (1.80e-2)" 6.8 2.5 7.9 0.5 15.6 0.5 6.2 35.7 3.7 7.7 4.3 1.0 0.3 2.2 10.5 0.5 1.8 0.3 23.8 2.4 7.2 19.0 0.8 15.0 0.2 23.5 26.2 1.6 0.4 3.2 4.1 4.2 21.3 34.1 0.1 0.5 2.8 36.1 2.8 1.6 1.2 0.4 25.5 1.7 0.8 2.3 17.8 1.2 21.0 2.9 0.3 1.6 3.1 32.0 0.0 0.0 0.8 0.0 0.0 0.0 19.5 0.0 0.1 0.0 0.0 0.0 0.0 0.5 12.6 0.3 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.7 0.1 0.0 1.1 0.0 0.5 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 3.2 0.7 0.0 0.0 1.9 0.0 0.1 0.5 2.8 0.1 0.0 0.0 0.6 0.0 0.1 34.4 0.2 0.0 0.1 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 15.6 35.7 3.7 2.4 7.2 23.5 26.2 21.3 25.5 17.8 32.0 19.5 22.4 29.8 3.6 0.5 0.9 10.1 5.8 1.2 2.3 7.5 9.0 6.1 1.5 10.7 27.6 0.0 9.1 0.4 1.0 0.0 0.9 1.8 3.1 3.2 15.1 0.0 0.0 0.8 0.0 6.1 2.8 2.0 6.1 2.5 1.8 11.7 0.3 3.1 0.0 0.8 0.7 0.0 6.3 1.4 4.3 31.4 5.8 0.0 1.9 3.3 0.1 2.1 1.5 1.0 1.2 1.4 6.4 3.4 19.3 0.0 0.1 4.7 0.1 0.0 1.6 2.1 6.2 1.2 0.4 0.6 6.0 0.4 1.7 0.2 6.0 CUTA "ACHAP, C6orf82" ENSG00000112514 "CutA divalent cation tolerance homolog" O60888 6 33416442-33418317 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016787, HPA064369" Uncertain Approved "Plasma membrane,Focal adhesion sites" "Secreted to blood" NA NA 26000000 "Cluster 20: T-cells - T-cell receptor" "Cluster 35: Non-specific - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 32: Non-specific - Translation" "Plasma membrane, Focal adhesion sites" "CAB016787: , HPA064369: AB_2685248" "unprognostic (7.03e-2)" "unprognostic (5.44e-2)" "unprognostic (4.56e-2)" "unprognostic (8.91e-2)" "unprognostic (1.86e-1)" "unprognostic (1.03e-1)" "unprognostic (1.98e-2)" "prognostic favorable (8.50e-4)" "unprognostic (1.87e-1)" "unprognostic (2.78e-2)" "unprognostic (1.27e-3)" "unprognostic (1.91e-1)" "unprognostic (5.55e-2)" "unprognostic (9.90e-2)" "unprognostic (1.54e-1)" "unprognostic (7.94e-2)" "unprognostic (2.74e-1)" 129.0 268.0 155.3 60.3 165.9 93.9 132.4 166.2 177.1 159.6 196.0 156.7 104.5 158.7 184.8 106.4 144.4 95.1 151.1 159.6 169.9 200.3 217.8 118.3 99.0 166.1 158.3 193.8 186.3 177.2 346.6 81.5 169.6 153.8 71.2 60.3 179.2 113.0 142.8 149.5 129.1 80.1 161.9 147.1 177.5 74.2 160.9 82.7 201.6 89.2 82.5 128.2 121.9 173.0 244.5 142.0 242.7 293.8 177.6 173.9 109.7 224.0 430.1 433.1 462.7 147.5 154.1 166.1 162.2 269.1 316.0 152.4 154.5 231.3 248.9 153.2 295.1 171.8 228.9 397.0 226.3 134.2 135.9 224.7 195.8 209.8 179.8 303.7 118.8 180.9 212.9 348.7 325.1 187.2 222.0 305.1 213.8 222.6 187.5 235.9 141.8 456.4 310.1 112.3 451.7 225.4 136.2 231.3 425.8 135.5 170.8 308.7 121.3 222.6 190.0 166.5 229.8 341.7 363.9 189.5 202.9 304.9 189.3 207.8 179.2 103.6 225.8 138.1 335.1 315.7 360.7 274.6 163.6 266.5 366.5 279.2 25.6 306.9 97.2 120.0 421.9 400.4 155.3 165.9 166.2 177.1 159.6 169.9 166.1 158.3 169.6 161.9 160.9 173.0 109.5 131.4 119.3 14.0 209.5 230.6 287.9 424.5 266.9 92.6 401.0 488.6 138.2 237.4 239.7 316.3 68.8 361.6 186.2 154.0 283.7 188.3 85.4 181.8 177.9 114.7 292.1 111.7 13.0 141.0 235.5 181.4 105.5 156.8 169.9 122.6 134.2 340.1 328.6 77.4 17.4 320.1 360.1 167.1 197.1 345.2 200.0 139.2 316.6 10.3 140.0 179.7 216.3 14.1 31.2 113.3 223.9 191.5 375.7 243.3 306.6 559.1 229.5 85.9 92.1 131.1 226.7 111.0 106.4 203.5 230.4 242.9 242.4 217.8 341.3 268.4 DCAF6 "IQWD1, PC326" ENSG00000143164 "DDB1 and CUL4 associated factor 6" Q58WW2 1 167935783-168075843 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "skeletal muscle: 641.3;tongue: 470.8" "Cell type enhanced" "Detected in all" "Early spermatids: 438.6;Excitatory neurons: 243.8;Late spermatids: 700.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054305 Supported "Nucleoplasm,Focal adhesion sites" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Focal adhesion sites" "HPA054305: AB_2682444" "unprognostic (1.54e-1)" "unprognostic (2.11e-1)" "unprognostic (1.42e-1)" "unprognostic (2.31e-1)" "unprognostic (2.20e-1)" "unprognostic (1.19e-1)" "unprognostic (5.42e-2)" "unprognostic (1.81e-1)" "unprognostic (1.51e-1)" "unprognostic (2.12e-1)" "unprognostic (1.74e-1)" "unprognostic (3.20e-2)" "unprognostic (9.21e-2)" "unprognostic (7.06e-2)" "unprognostic (6.00e-2)" "unprognostic (1.04e-1)" "unprognostic (1.49e-1)" 29.1 45.9 12.8 16.2 17.5 24.6 29.3 9.3 22.4 32.9 22.1 36.8 21.7 24.7 19.5 29.7 25.6 27.5 129.9 20.5 7.0 28.6 95.1 25.4 17.7 5.6 8.8 25.3 20.9 34.5 19.9 27.3 5.8 35.4 29.3 21.3 28.8 25.3 641.3 21.9 21.5 33.8 5.7 18.5 28.2 82.6 12.3 24.4 23.5 470.8 21.4 28.1 20.1 14.0 64.8 30.0 16.4 27.0 52.7 74.3 57.4 64.9 95.3 44.5 65.7 50.4 53.1 52.8 36.9 83.3 21.4 47.4 25.8 47.9 62.4 30.2 27.6 56.5 42.8 36.4 42.4 25.7 26.1 53.2 47.4 42.3 35.0 67.4 49.1 16.9 64.8 42.9 66.3 14.8 28.9 23.3 10.6 36.0 33.1 21.9 34.0 41.7 110.6 30.9 24.2 19.2 51.8 47.0 36.6 33.9 80.8 31.3 70.3 44.6 27.5 44.0 27.3 45.4 39.3 41.3 59.9 21.6 18.6 5.4 5.5 10.4 4.9 7.5 5.2 4.8 3.9 4.3 6.0 3.3 3.5 4.6 5.7 3.7 12.0 3.6 4.8 4.0 12.8 17.5 9.3 22.4 20.5 7.0 5.6 8.8 5.8 5.7 12.3 14.0 22.9 57.7 43.3 81.3 22.5 57.9 30.5 32.1 33.0 14.7 26.7 19.3 216.3 48.6 43.4 25.8 22.9 75.7 19.7 28.1 17.6 33.0 438.6 39.3 24.1 25.3 21.1 111.9 243.8 19.3 32.4 42.7 39.3 35.5 19.6 73.0 23.6 95.4 19.6 5.0 90.0 27.9 26.4 44.0 38.3 700.1 57.5 23.6 37.4 70.3 113.0 15.9 18.6 108.6 71.0 21.2 26.7 48.5 31.1 35.6 35.7 34.9 52.3 18.4 32.9 29.1 30.6 108.3 64.1 34.6 39.8 81.3 22.2 81.5 33.0 29.0 DLGAP4 "DAP4, KIAA0964, SAPAP4" ENSG00000080845 "DLG associated protein 4" Q9Y2H0 20 36306336-36528637 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 213.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-138 MG: 212.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054105, HPA056378" Approved Approved "Nucleoplasm,Focal adhesion sites" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Focal adhesion sites" "HPA054105: AB_2682381, HPA056378: " "unprognostic (1.11e-1)" "unprognostic (1.42e-1)" "unprognostic (9.00e-2)" "prognostic unfavorable (2.24e-5)" "unprognostic (1.35e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (3.73e-6)" "unprognostic (1.23e-1)" "prognostic favorable (9.88e-5)" "unprognostic (1.28e-1)" "unprognostic (2.18e-2)" "unprognostic (8.45e-2)" "prognostic unfavorable (2.48e-4)" "unprognostic (1.07e-1)" "unprognostic (1.13e-1)" "unprognostic (1.37e-1)" "unprognostic (1.53e-1)" 55.4 47.5 39.0 23.5 31.4 7.5 40.3 2.8 45.9 51.7 2.6 71.4 21.2 64.5 12.5 31.7 45.2 26.4 58.4 39.3 12.3 34.3 37.3 60.5 16.6 5.4 18.1 48.4 47.8 13.8 36.4 26.5 10.5 44.7 15.0 25.4 37.8 30.6 130.8 86.8 37.1 42.5 2.8 32.9 36.5 29.3 29.1 14.7 43.3 45.9 14.8 56.2 46.6 20.6 49.9 44.2 53.0 44.1 49.0 79.9 53.2 73.2 66.5 70.0 48.2 67.4 30.9 14.0 38.5 103.3 61.9 46.7 14.3 75.1 51.8 22.5 5.2 31.8 22.7 46.2 70.9 12.9 26.5 52.9 57.0 83.1 57.6 54.2 69.7 19.5 22.5 37.2 53.6 37.0 26.3 49.0 23.2 36.2 93.4 26.1 14.0 19.4 33.0 24.3 34.8 47.9 48.0 96.0 60.0 53.7 55.3 22.3 71.2 212.1 64.6 92.6 40.9 12.7 9.8 15.1 84.9 16.2 85.4 2.7 16.5 26.9 15.0 17.3 11.9 19.5 13.5 10.7 14.5 20.8 10.1 8.1 23.6 9.6 17.9 17.4 11.9 12.6 39.0 31.4 2.8 45.9 39.3 12.3 5.4 18.1 10.5 2.8 29.1 20.6 30.4 16.0 20.5 34.0 25.2 66.4 53.8 30.6 9.1 34.9 30.2 21.0 27.9 22.8 22.9 12.9 8.4 23.1 23.7 27.2 7.9 53.0 69.9 25.9 47.7 36.6 63.3 4.4 77.9 55.7 52.3 40.1 23.4 29.4 12.6 35.7 27.8 17.5 27.2 74.0 93.4 35.0 20.3 22.4 54.4 213.4 29.8 23.9 10.6 37.5 47.5 38.7 21.6 81.4 13.2 84.4 25.0 26.4 8.9 72.9 25.8 20.4 28.3 29.5 72.3 28.8 51.0 13.7 30.3 13.2 71.7 55.1 20.7 29.8 20.6 52.3 DOK5 "C20orf180, dJ805C22.1" ENSG00000101134 "Docking protein 5" Q9P104 20 54475593-54651169 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 46.0;tongue: 24.3" "Cell type enhanced" "Detected in many" "Astrocytes: 110.7;Distal tubular cells: 39.2;Excitatory neurons: 49.7;Horizontal cells: 38.7;Inhibitory neurons: 79.6;Muller glia cells: 63.9;Oligodendrocyte precursor cells: 58.3" "Group enriched" "Detected in many" 6 "glioma: 18.0;ovarian cancer: 29.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 32.9;ASC diff: 13.1;ASC TERT1: 11.0;hTEC/SVTERT24-B: 13.7;U-138 MG: 51.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054460, HPA065235" Uncertain Approved "Focal adhesion sites" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Focal adhesion sites" "HPA054460: AB_2682495, HPA065235: AB_2685441" "unprognostic (2.69e-1)" "unprognostic (1.49e-1)" "unprognostic (8.90e-2)" "prognostic unfavorable (8.99e-7)" "unprognostic (1.02e-1)" "unprognostic (1.72e-2)" "unprognostic (5.88e-4)" "unprognostic (5.12e-2)" "unprognostic (4.51e-3)" "unprognostic (2.97e-1)" "unprognostic (2.69e-2)" "unprognostic (1.49e-1)" "unprognostic (6.49e-2)" "unprognostic (4.23e-3)" "unprognostic (3.08e-1)" "unprognostic (4.56e-2)" "unprognostic (1.99e-2)" 2.9 1.9 14.6 1.7 14.2 0.0 1.9 13.4 15.6 1.1 13.0 1.4 0.3 1.7 0.3 1.7 12.2 9.8 18.4 15.4 16.9 5.2 2.3 1.0 0.6 15.9 14.7 0.9 1.2 0.2 1.1 1.8 18.6 0.9 0.7 11.7 1.4 0.8 46.0 0.5 0.7 2.8 13.9 0.3 0.8 1.7 15.3 0.4 5.1 24.3 0.4 4.7 0.9 13.3 0.0 0.0 32.9 0.0 13.1 11.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 5.7 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 4.3 0.0 13.7 0.0 0.6 1.7 0.0 0.0 4.0 0.1 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 3.6 7.0 0.0 8.6 0.0 0.0 0.1 0.4 1.9 0.0 0.0 0.0 51.3 3.2 1.4 0.0 0.0 0.0 0.1 2.3 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 14.2 13.4 15.6 15.4 16.9 15.9 14.7 18.6 13.9 15.3 13.3 4.8 0.0 0.0 110.7 0.3 0.3 2.3 0.0 0.0 12.3 6.7 6.2 7.3 12.8 0.0 11.0 6.2 0.3 0.1 0.0 39.2 17.7 2.3 0.4 1.5 3.3 0.0 0.0 49.7 1.2 0.6 14.4 0.0 10.6 0.0 28.6 17.5 0.0 29.0 38.7 79.6 0.0 0.0 0.6 2.5 4.5 2.5 0.6 0.0 9.4 14.5 63.9 0.0 58.3 2.1 2.2 0.0 1.2 0.1 2.0 0.0 0.2 0.0 8.1 0.0 2.8 5.3 3.7 1.5 0.0 0.4 0.8 0.2 1.6 0.0 0.9 DOK6 "DOK5L, HsT3226, MGC20785" ENSG00000206052 "Docking protein 6" Q6PKX4 18 69400888-69849087 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.8;parathyroid gland: 12.5;retina: 22.3" "Group enriched" "Detected in many" 4 "Bipolar cells: 230.4;Excitatory neurons: 236.8;Inhibitory neurons: 259.1;Oligodendrocyte precursor cells: 178.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 10.5;Hep G2: 11.1;RPMI-8226: 10.5;SCLC-21H: 4.7;SH-SY5Y: 10.5;SuSa: 7.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041099, HPA063534" Approved Approved "Focal adhesion sites,Cytosol" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 56: Bipolar cells - Visual perception" "Focal adhesion sites, Cytosol" "HPA041099: AB_2677299, HPA063534: AB_2685032" "unprognostic (5.83e-2)" "unprognostic (1.39e-1)" "unprognostic (2.06e-1)" "unprognostic (1.21e-1)" "unprognostic (2.77e-2)" "unprognostic (2.59e-1)" "unprognostic (1.55e-1)" "unprognostic (1.90e-2)" "unprognostic (8.62e-2)" "unprognostic (5.99e-2)" "unprognostic (1.04e-2)" "unprognostic (4.60e-3)" "unprognostic (2.13e-4)" "unprognostic (2.30e-3)" "unprognostic (2.88e-2)" "unprognostic (4.49e-3)" "unprognostic (1.09e-3)" 1.1 0.7 8.8 0.7 10.3 0.1 0.5 0.9 14.0 1.8 0.0 0.6 0.3 1.5 0.5 0.7 0.7 3.2 6.2 17.8 10.6 4.9 2.4 2.4 0.5 10.9 11.6 2.2 0.2 12.5 0.7 5.9 9.7 1.3 0.5 22.3 0.8 2.1 0.1 0.5 0.5 2.5 4.1 0.9 0.7 1.5 6.5 0.1 2.2 0.6 0.5 3.1 1.1 5.8 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.2 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.1 0.0 11.1 0.3 0.0 0.2 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 10.5 0.0 0.0 4.7 10.5 0.0 0.0 0.0 7.6 0.0 0.0 0.0 4.0 0.6 0.0 1.5 0.3 0.0 0.0 3.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 10.3 0.9 14.0 17.8 10.6 10.9 11.6 9.7 4.1 6.5 5.8 0.5 0.0 0.0 9.8 0.0 0.3 0.1 0.0 0.0 230.4 0.1 0.0 9.1 0.0 1.3 0.0 14.6 0.0 1.2 0.0 1.9 0.0 45.3 0.4 13.3 1.5 0.0 0.0 236.8 0.0 0.0 6.7 0.0 0.3 0.0 17.2 0.0 0.9 0.0 10.1 259.1 0.0 0.0 0.3 0.8 30.6 1.5 2.1 0.0 8.4 0.1 6.9 2.1 178.4 6.4 0.0 0.0 6.8 0.7 0.1 0.0 9.6 0.0 14.6 0.0 0.4 5.5 0.9 1.1 0.1 0.6 0.0 1.2 4.9 0.0 0.1 EIF2B2 "EIF-2Bbeta, EIF2B" ENSG00000119718 "Eukaryotic translation initiation factor 2B subunit beta" P49770 14 75002921-75012366 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 165.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005841, CAB037105, HPA048028" Enhanced Approved "Nucleoplasm,Plasma membrane,Focal adhesion sites" NA NA 12000 "Cluster 44: Non-specific - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane, Focal adhesion sites" Nucleoplasm "CAB037105: AB_1840834, HPA005841: AB_1078725, HPA048028: AB_2680235" "unprognostic (1.10e-1)" "unprognostic (4.41e-2)" "unprognostic (5.70e-2)" "unprognostic (6.71e-2)" "unprognostic (7.64e-2)" "unprognostic (3.45e-3)" "prognostic unfavorable (2.26e-6)" "unprognostic (1.48e-1)" "unprognostic (1.23e-1)" "unprognostic (1.65e-2)" "unprognostic (4.95e-2)" "unprognostic (1.01e-1)" "prognostic favorable (2.95e-4)" "unprognostic (4.15e-2)" "unprognostic (2.74e-1)" "unprognostic (1.44e-1)" "unprognostic (3.28e-2)" 2.7 5.3 4.0 2.9 4.5 3.2 3.6 8.7 4.8 3.9 2.2 3.0 3.0 3.6 4.9 3.8 3.1 4.0 3.9 3.6 6.1 4.9 3.3 2.7 4.0 4.5 4.2 2.9 4.0 8.5 3.5 4.8 4.5 4.1 3.8 6.8 2.8 4.5 5.5 4.0 2.8 3.4 2.9 2.7 2.6 3.9 4.8 3.9 11.5 7.1 4.2 4.0 2.6 6.9 5.9 7.0 5.6 6.4 6.3 5.2 7.4 3.7 6.1 7.1 8.2 9.0 5.9 5.2 2.3 5.8 4.5 4.4 8.8 8.7 10.6 3.2 6.5 4.6 6.3 6.2 8.2 3.4 5.3 4.8 8.2 9.1 9.3 6.1 24.8 4.5 4.2 4.9 15.5 17.4 5.5 4.3 4.0 7.3 10.3 3.4 6.6 4.3 10.1 7.0 6.0 4.8 3.9 5.5 8.4 6.9 9.0 3.2 6.4 5.4 5.2 2.4 4.8 8.4 7.5 6.2 5.9 4.3 4.2 4.2 1.8 1.4 3.0 1.9 2.5 2.1 2.6 2.5 2.4 2.0 1.9 2.0 1.0 3.3 1.8 2.0 4.0 2.5 4.0 4.5 8.7 4.8 3.6 6.1 4.5 4.2 4.5 2.9 4.8 6.9 18.9 19.2 11.5 6.2 14.1 17.7 19.5 28.9 18.2 28.2 15.4 17.0 18.2 22.8 21.5 25.8 45.9 51.5 16.1 15.3 41.1 36.2 12.1 17.0 14.5 32.1 15.6 20.8 5.3 33.1 56.5 18.3 12.8 12.8 21.5 17.5 13.2 11.9 33.7 28.6 5.4 9.0 20.3 19.1 11.9 12.7 15.8 18.8 14.2 1.9 28.0 27.3 28.8 2.5 8.5 28.1 11.7 16.1 11.3 17.5 19.0 50.8 17.2 29.4 26.3 16.9 27.9 84.2 27.4 27.3 21.9 165.5 14.9 30.5 19.7 19.2 ENAH "FLJ10773, MENA, NDPP1" ENSG00000154380 "ENAH actin regulator" Q8N8S7 1 225486835-225653142 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028448, HPA028696" Enhanced Enhanced "Plasma membrane,Focal adhesion sites,Cytosol" NA NA 15000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Focal adhesion sites, Cytosol" "HPA028448: AB_10600766, HPA028696: AB_10611249" "unprognostic (2.56e-2)" "unprognostic (8.03e-2)" "unprognostic (1.09e-1)" "unprognostic (4.35e-2)" "unprognostic (5.61e-3)" "unprognostic (2.85e-1)" "unprognostic (1.21e-3)" "unprognostic (2.30e-1)" "unprognostic (2.23e-1)" "unprognostic (9.22e-2)" "unprognostic (4.71e-3)" "unprognostic (2.14e-1)" "unprognostic (2.24e-3)" "unprognostic (8.84e-2)" "unprognostic (5.83e-2)" "unprognostic (7.92e-2)" "unprognostic (2.93e-2)" 26.3 20.2 30.3 16.5 25.9 0.5 13.4 21.1 20.3 13.5 2.0 30.9 12.5 23.6 13.7 16.2 15.0 23.6 25.2 27.2 35.7 7.0 7.5 17.3 4.7 35.5 34.2 22.6 22.3 17.9 6.5 18.2 28.1 21.4 10.1 8.1 20.9 30.6 20.4 10.6 10.8 57.6 22.4 24.8 23.3 25.0 40.9 9.0 7.3 11.5 4.6 30.1 13.8 28.7 91.6 71.9 87.1 79.0 33.3 43.7 111.9 99.1 47.3 58.4 43.9 46.4 33.0 38.7 256.8 153.9 52.5 79.0 102.7 37.4 55.2 0.6 63.4 40.3 62.4 63.1 99.4 4.8 1.5 67.9 44.2 75.9 96.2 47.8 47.0 10.7 2.7 1.9 58.6 17.7 18.5 4.7 146.8 23.9 64.3 27.6 122.9 1.1 26.9 69.5 85.3 68.9 194.6 73.3 63.3 66.1 87.5 5.9 92.2 150.4 109.8 126.8 198.6 4.2 11.4 25.7 82.7 5.0 78.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 30.3 25.9 21.1 20.3 27.2 35.7 35.5 34.2 28.1 22.4 40.9 28.7 117.0 12.8 37.3 81.9 3.8 129.0 172.5 64.4 26.2 11.2 96.2 57.9 119.3 54.3 56.5 22.0 62.6 65.0 1.7 14.8 3.9 84.7 74.8 127.2 60.5 79.3 41.4 0.0 86.3 100.5 18.5 71.6 63.2 75.0 5.1 194.2 23.9 12.9 11.2 16.8 155.0 27.3 26.4 1.6 29.7 24.3 58.1 4.3 83.6 41.2 3.8 32.6 3.1 160.4 151.3 61.5 16.5 168.9 1.6 133.1 3.5 19.6 137.8 19.0 92.1 69.4 166.1 13.4 37.2 25.6 134.1 60.5 4.8 220.7 31.3 100.3 EXD3 "FLJ20433, LOC54932, mut-7, Nbr" ENSG00000187609 "Exonuclease 3'-5' domain containing 3" Q8N9H8 9 137306896-137423211 "Predicted intracellular proteins" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 73.2;Paneth cells: 178.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 29.4" "Low region specificity" "Detected in all" HPA047395 Approved Approved "Actin filaments,Focal adhesion sites" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 72: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Focal adhesion sites" "Actin filaments" "HPA047395: AB_10962864" "unprognostic (2.91e-1)" "unprognostic (5.67e-2)" "unprognostic (1.75e-3)" "prognostic favorable (4.30e-4)" "unprognostic (1.88e-1)" "unprognostic (1.70e-1)" "unprognostic (6.65e-2)" "unprognostic (1.37e-1)" "unprognostic (2.54e-2)" "unprognostic (1.10e-1)" "unprognostic (2.50e-3)" "unprognostic (1.72e-2)" "unprognostic (5.21e-2)" "unprognostic (7.99e-3)" "unprognostic (2.05e-1)" "unprognostic (8.67e-2)" "unprognostic (5.05e-2)" 9.4 10.1 6.2 3.5 6.8 3.5 10.8 5.9 11.0 11.5 6.6 16.0 9.4 9.9 1.5 11.6 12.3 4.2 11.2 6.5 5.8 12.2 8.1 10.2 3.8 7.2 6.1 10.7 9.8 3.7 13.5 3.4 6.4 14.5 3.6 0.8 10.1 3.7 9.5 10.2 11.3 1.4 5.5 14.8 12.3 4.8 6.1 1.1 11.4 2.6 2.3 10.9 11.2 6.3 8.3 7.0 3.3 9.5 2.8 4.0 7.8 4.0 4.5 3.5 5.3 4.8 17.5 3.5 9.1 3.1 8.7 14.5 1.0 4.4 1.1 8.2 8.1 2.6 13.0 7.9 8.5 1.9 29.4 4.8 6.0 3.1 2.8 10.2 11.9 0.0 7.0 6.4 3.0 22.3 0.1 6.9 3.8 18.1 4.7 6.3 2.6 25.3 7.1 4.7 4.5 7.7 4.0 8.4 3.8 3.8 13.6 9.3 15.0 4.8 4.4 7.5 6.2 8.1 4.1 3.0 8.7 6.4 7.4 10.7 3.4 7.8 2.2 4.5 2.7 2.6 4.0 2.1 3.9 2.4 3.1 2.5 0.8 4.1 4.4 2.5 6.1 2.3 6.2 6.8 5.9 11.0 6.5 5.8 7.2 6.1 6.4 5.5 6.1 6.3 17.6 0.0 6.3 24.2 5.3 5.9 10.0 8.9 13.6 14.6 13.5 17.0 5.2 10.0 11.2 7.3 14.6 9.9 8.1 46.4 9.8 6.8 17.9 11.5 6.5 14.1 7.3 5.0 21.6 11.3 3.3 7.3 19.4 13.1 61.7 10.5 17.2 7.2 9.2 21.9 24.1 27.6 16.2 5.4 7.3 73.2 5.9 6.9 3.6 13.1 6.2 10.0 12.3 26.2 14.6 6.4 178.2 7.9 6.6 10.0 31.3 11.9 9.3 10.4 13.1 5.5 9.9 2.3 8.9 9.9 8.9 4.0 6.4 19.5 39.0 9.2 FABP3 "FABP11, H-FABP, MDGI, O-FABP" ENSG00000121769 "Fatty acid binding protein 3" P05413 1 31365253-31376850 "Candidate cardiovascular disease genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 14 "heart muscle: 5666.1;skeletal muscle: 2202.5;tongue: 1442.4" "Cell type enhanced" "Detected in many" "Breast glandular cells: 629.8;Cardiomyocytes: 2495.2;Distal tubular cells: 452.0;Proximal tubular cells: 703.6" "Cancer enhanced" "Detected in all" "renal cancer: 92.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 4 "ASC TERT1: 215.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017830, HPA055754" Enhanced Uncertain "Golgi apparatus,Plasma membrane,Focal adhesion sites" NA NA 1640000 3000000 "Cluster 22: NK-cells - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" "Focal adhesion sites" "Golgi apparatus, Plasma membrane" "CAB017830: , HPA055754: AB_2682909" "unprognostic (2.07e-2)" "unprognostic (2.50e-2)" "unprognostic (1.32e-3)" "unprognostic (1.73e-2)" "unprognostic (2.05e-1)" "unprognostic (1.62e-1)" "unprognostic (6.07e-3)" "unprognostic (1.04e-1)" "unprognostic (6.86e-2)" "unprognostic (1.18e-1)" "unprognostic (2.85e-1)" "unprognostic (1.67e-1)" "prognostic favorable (1.54e-7)" "unprognostic (5.80e-3)" "unprognostic (3.45e-1)" "unprognostic (7.38e-3)" "unprognostic (9.76e-3)" 31.4 63.5 33.7 2.1 39.2 1.6 95.4 42.3 51.5 40.4 14.8 16.3 0.8 93.9 6.4 9.5 37.2 3.7 5666.1 52.0 37.3 229.8 6.6 26.4 3.4 50.5 38.3 20.3 2.2 0.3 9.0 2.8 55.2 48.9 4.8 17.8 46.5 52.2 2202.5 16.3 7.5 44.2 31.4 28.8 60.3 15.3 36.1 2.3 6.8 1442.4 1.4 12.5 32.5 36.8 1.0 0.4 8.8 1.1 50.6 215.0 2.0 2.6 17.3 0.3 6.6 1.3 1.9 1.6 17.8 5.2 0.3 2.1 2.5 0.0 0.5 0.8 3.7 1.8 2.7 5.3 2.2 1.7 0.5 16.9 0.0 3.9 0.0 2.5 0.0 1.4 2.2 0.5 2.2 0.5 0.7 1.5 11.4 0.9 3.1 0.4 5.7 0.6 4.1 0.7 2.1 0.5 1.5 0.7 28.4 13.2 0.9 3.1 1.7 1.0 1.0 6.0 1.3 1.0 2.3 1.3 2.9 1.5 1.7 0.0 0.1 0.0 0.2 0.2 0.2 0.2 0.1 0.3 0.1 0.2 0.1 0.4 0.0 0.2 0.1 0.1 0.1 0.1 33.7 39.2 42.3 51.5 52.0 37.3 50.5 38.3 55.2 31.4 36.1 36.8 4.9 0.0 1.7 2.9 7.7 3.6 1.5 0.4 0.0 6.1 629.8 13.2 2495.2 2.8 1.3 27.6 2.1 3.8 2.1 0.4 452.0 0.4 2.5 0.4 0.5 25.6 0.0 0.0 16.1 0.4 1.4 67.2 1.1 3.1 1.3 43.8 2.2 0.1 114.7 8.4 14.6 0.1 0.0 27.8 10.3 5.4 6.8 19.1 8.8 3.7 0.0 2.6 0.0 3.5 8.9 0.3 12.3 7.9 0.1 6.8 0.1 703.6 1.5 10.2 0.0 14.9 40.7 2.9 0.2 0.2 3.0 1.6 5.1 97.9 0.3 36.5 FBLIM1 "CAL, FBLP-1, migfilin" ENSG00000162458 "Filamin binding LIM protein 1" Q8WUP2 1 15756607-15786594 "Predicted intracellular proteins" "Cell adhesion, Cell shape" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 207.3;Paneth cells: 153.6;Peritubular cells: 191.5;Proximal enterocytes: 145.9;Sertoli cells: 144.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.7" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 255.9;TIME: 420.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA025287, HPA072750" Approved Enhanced "Nucleoli fibrillar center,Cell Junctions,Focal adhesion sites" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions, Focal adhesion sites" "Nucleoli fibrillar center" "HPA025287: AB_1848443, HPA072750: AB_2686554" "unprognostic (4.10e-2)" "prognostic unfavorable (4.07e-4)" "unprognostic (2.26e-1)" "unprognostic (5.33e-2)" "unprognostic (2.46e-2)" "unprognostic (1.52e-1)" "unprognostic (9.33e-2)" "unprognostic (8.77e-3)" "prognostic unfavorable (6.15e-4)" "unprognostic (2.02e-1)" "unprognostic (1.67e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (8.64e-4)" "unprognostic (8.33e-2)" "unprognostic (3.01e-1)" "unprognostic (1.08e-1)" "unprognostic (8.21e-2)" 32.4 17.9 2.7 21.5 3.3 0.8 28.1 3.2 4.8 43.2 5.2 75.6 82.2 75.7 15.6 24.1 43.5 69.8 45.6 2.5 2.4 26.7 7.1 39.3 9.6 2.6 3.2 39.1 27.5 36.2 11.0 29.4 2.9 47.0 53.2 1.8 31.7 63.1 5.4 16.8 86.1 47.1 2.5 27.6 64.0 12.8 3.8 2.8 17.6 5.6 6.8 44.6 29.3 2.6 34.2 17.2 15.9 0.6 3.7 8.1 21.6 55.2 84.3 38.4 30.4 6.0 48.8 0.3 114.5 87.8 67.3 62.5 11.3 121.0 19.2 0.3 6.6 0.2 4.7 31.7 98.5 0.2 0.6 39.7 81.7 31.9 75.1 82.7 255.9 2.0 1.2 7.6 13.2 0.8 0.6 1.1 16.5 50.9 25.0 0.1 0.4 1.0 51.4 22.1 0.2 38.9 29.0 3.4 6.0 33.9 6.8 0.6 420.4 50.7 7.1 0.8 25.7 0.4 1.0 0.5 8.0 0.2 0.5 1.7 0.3 0.3 0.2 0.1 0.2 0.3 0.2 0.2 0.1 0.5 0.3 0.3 0.8 0.4 0.2 0.4 0.1 0.1 2.7 3.3 3.2 4.8 2.5 2.4 2.6 3.2 2.9 2.5 3.8 2.6 10.8 12.8 18.1 0.0 3.1 86.3 82.7 41.4 20.5 3.7 28.6 23.9 37.1 47.1 30.6 16.5 6.2 8.9 4.8 207.3 0.0 99.1 3.4 13.6 75.9 19.2 46.0 0.0 0.7 53.5 114.2 29.3 133.5 20.5 18.9 9.4 55.0 2.5 5.6 1.7 5.5 54.8 26.4 1.9 23.5 4.0 80.2 5.8 14.2 2.8 2.7 9.1 1.0 1.0 1.2 113.0 153.6 191.5 1.2 29.8 145.9 2.5 11.6 6.4 144.7 11.9 64.8 2.8 1.9 17.4 62.8 19.4 6.0 6.6 53.8 62.6 FBXO28 "CENP-30, Fbx28, FLJ10766, KIAA0483" ENSG00000143756 "F-box protein 28" Q9NVF7 1 224114111-224162047 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003289 Approved Supported "Nucleoplasm,Focal adhesion sites" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 17: WM-115 - Nervous system development" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "Focal adhesion sites" "HPA003289: AB_2666879" "unprognostic (4.91e-2)" "unprognostic (5.57e-2)" "unprognostic (1.78e-2)" "unprognostic (1.03e-1)" "unprognostic (1.33e-2)" "unprognostic (1.43e-1)" "unprognostic (2.12e-1)" "unprognostic (8.25e-2)" "unprognostic (2.03e-1)" "unprognostic (7.09e-2)" "unprognostic (5.09e-3)" "unprognostic (2.60e-1)" "unprognostic (1.98e-3)" "unprognostic (9.46e-2)" "unprognostic (1.71e-1)" "unprognostic (1.41e-1)" "unprognostic (2.61e-1)" 10.9 7.5 6.5 8.3 7.3 8.9 12.3 8.8 10.5 10.9 7.4 10.3 8.5 10.0 7.9 12.4 8.2 9.5 8.1 7.6 9.1 13.6 17.4 8.9 10.5 8.5 7.4 11.3 7.6 13.7 4.4 9.0 8.8 10.0 10.6 8.3 7.9 8.5 12.5 21.1 7.7 9.8 8.0 8.9 8.5 7.8 7.8 10.9 9.8 14.2 10.6 11.5 9.0 8.9 24.6 10.6 16.2 17.4 16.6 19.0 26.7 24.3 19.7 16.0 15.2 14.9 18.7 11.8 24.4 22.3 10.3 20.9 24.2 23.4 27.4 17.0 27.0 15.0 12.8 10.7 20.7 28.3 18.8 18.6 27.7 23.2 41.9 18.8 27.1 15.0 24.8 16.4 29.1 8.1 14.9 14.4 38.6 32.3 22.8 15.7 23.1 22.3 30.2 16.1 26.2 28.1 25.1 38.0 27.4 16.9 20.2 28.2 31.2 19.8 15.0 25.0 46.1 17.8 22.3 18.0 24.5 13.7 39.3 7.4 6.5 11.8 5.8 6.0 7.2 8.9 5.9 6.8 7.8 9.0 5.9 6.6 4.2 8.6 6.9 3.5 8.8 4.6 6.5 7.3 8.8 10.5 7.6 9.1 8.5 7.4 8.8 8.0 7.8 8.9 15.0 6.4 10.6 22.5 16.8 34.3 25.5 11.3 9.6 20.5 14.7 11.7 11.4 7.2 13.5 11.0 22.9 14.2 12.3 17.2 9.8 13.2 30.3 15.9 13.0 16.4 18.5 17.4 48.8 11.5 13.1 12.7 7.1 22.9 14.0 12.6 14.3 23.4 13.9 18.5 43.8 12.7 14.2 17.7 16.3 14.8 13.1 16.8 28.4 34.7 16.4 12.6 7.2 45.8 43.7 17.7 12.2 13.2 15.4 21.5 12.0 22.8 11.5 18.6 13.1 14.9 12.7 24.7 26.8 17.2 39.1 23.0 18.9 10.9 14.6 30.7 FCHSD2 "KIAA0769, SH3MD3" ENSG00000137478 "FCH and double SH3 domains 2" O94868 11 72836745-73142318 "Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 219.6;Microglial cells: 387.8;Oligodendrocyte precursor cells: 471.0;Oligodendrocytes: 198.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 164.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038545, HPA038546" Uncertain Approved "Nuclear speckles,Plasma membrane,Actin filaments,Focal adhesion sites" Yes No "Cluster 10: Basophils - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane, Actin filaments" "Nuclear speckles, Focal adhesion sites" "HPA038545: AB_2676074, HPA038546: AB_10673013" "unprognostic (1.80e-2)" "unprognostic (1.50e-2)" "prognostic favorable (1.71e-4)" "unprognostic (1.63e-1)" "unprognostic (3.14e-2)" "unprognostic (2.62e-3)" "unprognostic (1.41e-2)" "unprognostic (2.62e-1)" "unprognostic (1.27e-2)" "unprognostic (2.56e-1)" "unprognostic (3.69e-2)" "unprognostic (6.16e-2)" "unprognostic (2.89e-3)" "unprognostic (2.02e-1)" "unprognostic (4.70e-1)" "unprognostic (2.92e-1)" "unprognostic (1.23e-1)" 22.2 19.2 43.3 33.4 47.9 28.6 16.8 31.5 38.7 14.9 34.6 14.5 8.9 16.0 6.9 11.7 13.8 22.6 25.5 37.0 44.5 13.0 17.6 23.9 45.2 36.6 36.4 32.3 10.4 9.9 8.1 31.2 35.4 11.6 14.4 19.6 9.3 13.8 8.8 9.0 17.7 17.2 32.5 42.3 13.1 22.6 41.3 28.5 14.9 14.7 46.1 21.6 11.7 45.0 14.2 12.3 26.0 31.3 9.8 23.9 21.8 26.7 50.6 14.8 12.0 9.6 21.0 76.3 31.3 31.0 15.6 20.0 15.3 14.1 21.0 27.2 7.0 64.2 14.3 33.4 25.7 30.6 7.6 14.6 15.6 15.1 17.7 33.4 35.7 26.7 13.7 49.6 19.5 16.1 36.4 54.7 5.5 15.6 13.8 56.4 39.8 164.1 24.8 21.4 13.1 16.9 9.6 16.2 31.9 12.2 12.4 23.7 47.9 45.9 18.5 32.9 7.5 46.8 29.4 71.2 8.4 51.4 13.8 18.3 8.4 18.7 2.8 5.1 1.9 22.2 2.8 3.2 8.1 26.9 3.2 4.1 19.9 2.0 3.0 32.3 3.2 3.6 43.3 47.9 31.5 38.7 37.0 44.5 36.6 36.4 35.4 32.5 41.3 45.0 47.3 9.6 14.0 114.9 76.7 8.5 5.2 3.6 9.1 13.5 5.9 4.7 16.0 8.6 6.1 3.7 25.0 12.4 39.4 1.9 1.9 4.1 6.2 6.6 8.3 30.2 4.8 19.4 79.4 6.2 9.2 9.4 7.7 5.4 2.5 33.6 46.1 11.3 19.9 10.1 219.6 7.7 4.1 30.8 29.9 10.0 10.8 32.8 5.4 387.8 20.6 10.6 5.2 471.0 198.1 5.3 5.7 16.6 70.1 3.8 1.8 3.5 3.9 17.0 6.6 13.0 26.1 9.6 13.0 7.1 5.8 12.0 14.9 6.0 3.7 4.8 FCMR "FAIM3, TOSO" ENSG00000162894 "Fc fragment of IgM receptor" O60667 1 206903317-206923247 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 65.5;lymphoid tissue: 180.6" "Cell type enhanced" "Detected in many" "B-cells: 262.3;dendritic cells: 43.5;NK-cells: 108.1;T-cells: 74.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "RPMI-8226: 171.4;U-266/70: 73.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA003910 Approved Approved "Nucleoplasm,Focal adhesion sites,Cytosol" "Secreted to blood" NA NA 5500000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 57: B-cells - Immune response" "Focal adhesion sites, Cytosol" Nucleoplasm "HPA003910: AB_1078798" "prognostic favorable (4.23e-4)" "unprognostic (1.16e-3)" "unprognostic (7.48e-2)" "unprognostic (3.06e-3)" "unprognostic (2.04e-1)" "unprognostic (2.69e-3)" "unprognostic (1.15e-1)" "unprognostic (4.85e-3)" "unprognostic (1.03e-1)" "unprognostic (3.97e-1)" "unprognostic (3.23e-2)" "unprognostic (2.01e-1)" "unprognostic (8.15e-3)" "unprognostic (8.06e-2)" "unprognostic (2.12e-2)" "unprognostic (3.74e-2)" "unprognostic (5.05e-3)" 4.9 1.5 0.3 74.8 0.3 12.6 2.4 0.3 0.8 1.5 0.4 8.0 6.1 2.4 2.6 3.0 1.9 11.3 2.6 0.1 0.4 2.3 5.9 6.0 152.1 0.4 0.1 0.8 1.1 0.5 1.0 1.8 0.2 3.4 9.9 0.2 3.5 1.2 3.6 0.4 65.5 2.3 0.0 115.0 14.2 0.5 0.5 77.2 3.3 1.4 180.6 19.1 1.6 0.6 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.2 3.4 0.3 0.3 0.0 0.0 11.6 0.0 0.4 0.7 0.3 0.0 0.6 0.5 0.0 0.2 0.2 0.9 0.0 1.6 0.1 0.0 0.1 0.7 0.3 1.2 0.0 0.0 7.0 0.2 23.5 0.0 0.2 3.5 0.3 0.1 0.0 0.2 4.9 0.6 171.4 0.1 0.3 0.1 0.0 2.8 0.6 13.0 0.0 0.3 0.0 0.5 0.0 0.5 0.2 0.1 73.8 5.9 23.2 0.8 0.1 0.6 7.9 2.8 3.6 209.3 4.3 276.9 882.3 280.1 266.3 3.2 1057.5 483.2 336.0 56.0 218.8 4.3 13.7 687.7 416.6 0.3 0.3 0.3 0.8 0.1 0.4 0.4 0.1 0.2 0.0 0.5 0.6 1.3 0.0 3.9 0.0 262.3 0.0 4.9 0.0 1.2 0.0 3.5 3.0 3.6 5.7 1.3 0.0 0.0 0.1 43.5 0.9 0.0 1.7 0.2 0.8 0.7 1.7 0.0 8.4 0.0 2.9 0.1 3.4 4.1 0.9 0.0 0.6 4.6 1.4 4.4 0.0 0.0 0.6 0.0 5.7 0.0 0.4 0.3 8.1 0.0 0.0 3.6 0.0 108.1 0.0 0.0 1.2 0.3 0.0 30.5 2.9 0.1 1.0 0.7 0.0 0.0 0.2 2.9 0.1 2.3 1.7 0.0 0.0 74.9 0.0 1.9 6.8 FERMT2 "KIND2, mig-2, PLEKHC1, UNC112B" ENSG00000073712 "Fermitin family member 2" Q96AC1 14 52857268-52952435 "Predicted intracellular proteins" "Cell adhesion, Cell shape, Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040505, HPA072965" Uncertain Supported "Nucleoplasm,Focal adhesion sites,Cytosol" NA NA 230000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Focal adhesion sites" "Nucleoplasm, Cytosol" "HPA040505: AB_10673300, HPA072965: " "unprognostic (4.38e-2)" "unprognostic (4.25e-2)" "unprognostic (8.00e-3)" "unprognostic (2.42e-2)" "unprognostic (2.51e-2)" "unprognostic (4.89e-3)" "unprognostic (2.50e-2)" "unprognostic (1.92e-1)" "unprognostic (4.21e-2)" "unprognostic (1.07e-1)" "unprognostic (3.58e-1)" "unprognostic (1.99e-1)" "unprognostic (3.87e-2)" "unprognostic (3.96e-3)" "unprognostic (7.69e-2)" "unprognostic (3.14e-1)" "unprognostic (1.73e-3)" 148.4 21.2 28.7 38.8 31.6 0.5 57.6 29.0 37.3 44.7 18.0 104.3 13.1 105.1 26.3 46.8 55.7 65.7 66.9 31.0 27.4 55.4 108.3 47.9 15.3 35.7 29.1 43.6 20.6 18.4 13.1 116.5 33.5 69.1 33.3 29.5 22.6 117.9 48.8 13.4 29.3 155.6 30.6 37.6 46.4 15.5 27.6 6.9 35.9 69.6 6.6 77.7 29.1 38.1 22.8 18.9 101.6 46.8 163.7 133.7 84.6 148.4 95.2 172.3 107.9 34.1 17.6 0.1 49.4 153.1 33.8 9.6 80.1 11.1 128.3 0.2 22.6 31.9 83.1 40.3 209.6 0.4 12.6 129.4 23.5 95.3 125.4 78.5 91.2 16.8 0.6 153.4 131.7 28.0 7.7 0.5 64.3 0.2 51.3 3.9 103.8 0.4 60.9 20.6 6.2 130.5 157.8 35.0 37.7 103.3 30.1 1.1 115.2 134.5 92.4 108.2 56.0 22.6 29.4 0.6 30.9 0.2 33.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.7 31.6 29.0 37.3 31.0 27.4 35.7 29.1 33.5 30.6 27.6 38.1 152.7 76.9 42.0 116.5 1.0 18.6 150.6 15.5 13.6 39.5 33.8 41.4 65.8 24.3 25.6 40.5 37.5 74.8 2.3 0.2 31.3 48.5 68.2 20.1 141.7 110.4 0.0 2.7 13.7 33.2 178.1 103.9 3.6 40.2 58.3 31.6 110.3 82.3 10.4 15.2 16.1 0.5 4.1 8.9 19.5 27.9 74.9 4.4 46.2 29.0 4.8 52.3 1.0 41.2 92.0 27.6 0.1 174.9 4.5 40.0 0.0 44.7 10.1 56.0 151.2 83.4 174.1 4.1 16.2 2.2 8.1 102.6 7.9 12.3 0.4 37.0 FHL2 "DRAL, SLIM3" ENSG00000115641 "Four and a half LIM domains 2" Q14192 2 105357712-105438513 "Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "heart muscle: 1421.4;ovary: 535.4" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 1077.5;Extravillous trophoblasts: 585.9;Granulosa cells: 851.4;Leydig cells: 567.0;Peritubular cells: 1049.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 5.7" "Group enriched" "Detected in many" 6 "granulocytes: 5.7;T-cells: 2.7" "Cell line enhanced" "Detected in many" "LHCN-M2: 534.6;RPTEC TERT1: 489.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005922, HPA006028, CAB008368" Enhanced Enhanced "Actin filaments,Focal adhesion sites" NA Yes 14000 "Cluster 18: Basophils - Vesicular transport" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 22: Epithelial cell types - Mixed function" "Actin filaments, Focal adhesion sites" "CAB008368: AB_591383, HPA005922: AB_1078860, HPA006028: AB_1078858" "unprognostic (1.04e-1)" "unprognostic (1.63e-3)" "unprognostic (3.30e-1)" "unprognostic (3.42e-2)" "unprognostic (5.89e-2)" "prognostic unfavorable (2.01e-4)" "unprognostic (2.80e-2)" "unprognostic (1.02e-3)" "unprognostic (1.81e-1)" "unprognostic (2.42e-2)" "unprognostic (3.34e-2)" "unprognostic (8.11e-2)" "prognostic unfavorable (6.42e-5)" "unprognostic (2.06e-1)" "unprognostic (3.49e-1)" "unprognostic (9.92e-3)" "unprognostic (4.73e-2)" 68.3 70.2 10.4 28.9 13.2 17.0 65.4 7.6 18.2 101.9 15.0 75.2 48.5 105.1 33.8 55.4 55.8 81.5 1421.4 18.9 7.4 55.2 22.1 17.5 17.2 6.7 7.2 535.4 9.1 8.2 29.3 79.3 7.0 88.8 56.8 8.5 45.3 63.8 67.5 44.2 50.4 91.5 7.5 20.1 94.9 50.9 7.9 22.8 41.3 118.6 13.9 105.5 47.2 12.2 156.8 36.1 20.9 0.8 65.2 81.7 196.4 289.3 75.9 182.2 216.7 65.6 237.6 0.4 23.7 353.6 223.8 47.7 31.4 262.4 204.2 6.5 23.9 108.7 42.9 49.0 257.6 0.4 23.5 171.7 142.2 286.0 188.1 360.8 374.4 18.0 29.0 8.9 534.6 5.6 25.8 1.0 44.1 108.3 113.2 0.4 31.6 4.3 489.8 108.4 1.0 6.9 109.2 48.1 76.9 20.5 60.7 3.9 183.1 130.4 134.1 146.4 236.0 3.3 0.6 0.7 208.1 0.6 138.5 5.7 0.4 0.4 1.1 0.2 0.7 0.6 0.9 2.0 0.4 0.5 0.7 1.5 2.2 0.7 0.2 0.6 2.7 1.5 10.4 13.2 7.6 18.2 18.9 7.4 6.7 7.2 7.0 7.5 7.9 12.2 15.7 9.6 5.1 0.7 1.0 468.5 1077.5 342.5 389.9 9.5 59.8 126.2 362.1 15.7 91.0 29.5 2.1 220.4 1.7 212.6 3.9 100.7 5.7 44.8 40.4 27.4 58.2 63.5 46.3 117.9 585.9 96.1 186.1 32.5 10.2 851.4 17.2 9.2 25.3 0.0 4.9 169.8 73.2 0.6 31.8 17.3 567.0 10.4 23.2 25.3 2.7 1.6 0.0 0.5 1.6 234.5 258.2 1049.0 6.7 198.2 51.7 28.1 19.1 13.0 216.9 60.6 171.0 9.1 17.7 124.5 296.9 178.7 7.7 193.5 55.8 536.2 GAS7 "KIAA0394, MGC1348" ENSG00000007237 "Growth arrest specific 7" O60861 17 9910606-10198606 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 85.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 133.6;Fibroblasts: 79.6;Inhibitory neurons: 76.6;Late spermatids: 73.4;Oligodendrocytes: 163.3" "Group enriched" "Detected in all" 4 "glioma: 15.7;melanoma: 54.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 26.2" "Group enriched" "Detected in many" 4 "granulocytes: 17.1;monocytes: 26.2" "Cell line enriched" "Detected in many" 9 "WM-115: 533.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004838, HPA064678" Enhanced Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 6: Brain - Smell perception" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Actin filaments, Focal adhesion sites" "HPA004838: AB_2667263, HPA064678: AB_2685319" "unprognostic (1.68e-2)" "unprognostic (2.84e-3)" "unprognostic (1.80e-1)" "unprognostic (1.28e-3)" "unprognostic (1.15e-1)" "unprognostic (1.01e-2)" "unprognostic (7.32e-2)" "unprognostic (7.16e-2)" "unprognostic (2.88e-1)" "unprognostic (1.50e-2)" "unprognostic (2.48e-1)" "unprognostic (1.79e-1)" "unprognostic (1.94e-3)" "unprognostic (6.48e-2)" "unprognostic (8.78e-2)" "unprognostic (3.08e-2)" "prognostic unfavorable (6.89e-4)" 27.3 8.5 34.9 23.7 68.9 31.1 15.3 75.4 79.8 29.9 0.0 26.3 7.3 13.3 4.3 23.8 17.8 16.3 46.1 61.9 8.4 1.7 2.3 17.1 9.1 23.4 24.1 7.8 3.4 1.1 2.6 16.2 15.8 8.5 12.0 30.1 7.8 10.8 5.8 33.7 11.9 24.0 14.3 16.1 8.9 17.4 32.9 9.3 4.6 6.8 10.3 18.3 19.5 85.3 0.1 0.5 0.6 1.0 16.5 22.5 0.3 0.8 0.0 2.6 1.1 0.1 0.2 6.6 1.9 6.6 0.3 0.3 0.0 0.0 1.6 0.0 1.5 0.0 1.3 0.7 5.3 1.8 48.7 4.3 0.3 5.1 0.1 0.0 0.0 42.7 0.0 0.6 0.0 0.0 54.3 15.4 2.6 2.1 0.0 14.3 0.1 49.6 0.0 0.2 0.1 3.0 0.2 0.2 60.1 21.0 2.8 24.7 0.0 0.2 3.4 0.1 0.1 0.4 0.0 0.0 0.4 35.1 533.8 0.6 26.2 17.1 2.8 6.9 0.9 0.5 0.3 1.4 5.3 0.6 0.2 1.4 16.4 4.5 4.9 1.0 0.0 7.7 34.9 68.9 75.4 79.8 61.9 8.4 23.4 24.1 15.8 14.3 32.9 85.3 2.9 0.0 4.2 6.8 3.3 8.3 4.5 1.5 1.2 34.6 1.6 2.3 13.3 0.0 1.1 5.5 27.1 1.0 14.5 0.0 0.0 1.0 62.3 17.7 12.8 5.7 0.0 0.4 133.6 0.0 1.8 79.6 0.0 26.3 17.2 7.9 5.0 0.9 39.2 0.0 76.6 0.0 0.0 66.7 32.2 73.4 10.2 54.3 33.8 52.5 57.2 9.5 18.6 11.1 163.3 0.2 0.0 1.9 5.5 2.0 0.0 0.1 16.3 31.7 0.0 67.0 7.1 1.6 6.7 1.0 16.6 1.9 7.4 0.2 0.0 4.9 GFRAL "bA360D14.1, C6orf144, GRAL, UNQ9356" ENSG00000187871 "GDNF family receptor alpha like" Q6UXV0 6 55327469-55402493 "Predicted membrane proteins" Receptor "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047372 Uncertain Approved "Nucleoplasm,Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "Actin filaments, Focal adhesion sites" "HPA047372: AB_2680017" "unprognostic (2.31e-1)" 0.2 0.0 0.2 0.0 0.3 0.0 0.0 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.3 0.3 0.2 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GIT1 ENSG00000108262 "GIT ArfGAP 1" Q9Y2X7 17 29573475-29594054 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 122.3" "Cell type enhanced" "Detected in all" "Early spermatids: 97.8;Late spermatids: 99.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004059, HPA004186" Enhanced Supported "Focal adhesion sites,Mitochondria,Cytosol" NA NA 36000 "Cluster 15: NK-cells - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 34: Spermatids - Unknown function" "Focal adhesion sites, Cytosol" Mitochondria "HPA004059: AB_1078966, HPA004186: AB_1078967" "unprognostic (3.66e-1)" "unprognostic (4.46e-2)" "unprognostic (3.24e-2)" "unprognostic (6.30e-3)" "unprognostic (1.46e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (2.54e-6)" "unprognostic (3.00e-3)" "unprognostic (2.79e-1)" "unprognostic (5.23e-2)" "unprognostic (2.12e-2)" "unprognostic (3.08e-1)" "unprognostic (8.48e-2)" "unprognostic (5.56e-2)" "unprognostic (7.30e-2)" "unprognostic (2.10e-1)" "unprognostic (1.69e-1)" 30.2 13.5 79.4 18.0 89.3 14.4 29.9 29.1 122.3 22.0 14.9 20.5 17.9 20.9 7.6 28.6 22.5 15.5 28.9 101.2 38.0 18.4 7.6 34.8 21.3 42.5 45.3 21.3 21.9 18.0 23.7 21.1 39.7 21.3 10.1 12.1 19.0 14.4 31.9 34.2 20.5 12.9 31.7 22.3 19.1 88.8 51.8 23.1 23.2 18.5 15.2 21.6 23.6 62.1 49.7 80.9 39.1 69.9 30.4 19.1 45.3 23.9 23.4 28.2 25.1 33.1 18.0 37.3 37.3 31.5 50.5 79.5 41.6 61.4 14.4 48.3 49.7 26.9 39.8 29.8 37.0 34.4 21.3 23.4 69.2 32.4 50.5 40.0 53.0 48.6 22.3 31.2 20.5 50.9 109.0 45.7 29.2 49.9 19.2 81.7 52.3 55.6 25.8 26.7 82.0 70.0 33.8 77.2 117.7 27.9 38.0 45.0 66.2 26.7 38.2 59.3 49.0 25.8 39.3 41.5 43.9 29.0 45.9 0.1 1.6 1.4 1.9 2.5 0.9 0.7 1.9 2.1 2.2 0.6 1.6 1.1 0.5 2.4 1.8 1.8 1.3 1.8 79.4 89.3 29.1 122.3 101.2 38.0 42.5 45.3 39.7 31.7 51.8 62.1 54.6 3.2 1.5 21.9 9.5 27.1 6.7 9.2 10.2 15.5 12.6 16.3 8.7 4.3 4.9 5.5 10.4 5.1 17.3 19.2 1.9 7.5 97.8 9.4 16.8 30.8 14.9 1.7 16.8 9.4 8.0 9.7 11.2 10.5 1.3 17.9 22.5 4.0 8.3 11.8 14.1 13.8 8.2 9.5 18.9 99.2 14.3 10.6 8.8 15.9 7.4 13.3 9.2 12.5 16.9 9.5 11.5 10.5 8.7 13.4 17.2 6.1 9.8 10.2 13.1 17.3 9.5 30.5 11.5 14.4 28.1 3.6 12.4 8.6 14.6 8.3 GPBP1L1 SP192 ENSG00000159592 "GC-rich promoter binding protein 1 like 1" Q9HC44 1 45627304-45688113 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028593 Approved Approved "Nucleoplasm,Plasma membrane,Focal adhesion sites,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Plasma membrane, Focal adhesion sites, Cytosol" "HPA028593: AB_10602906" "unprognostic (1.39e-1)" "unprognostic (8.41e-2)" "unprognostic (1.44e-3)" "unprognostic (6.60e-2)" "unprognostic (6.35e-2)" "unprognostic (1.97e-3)" "unprognostic (2.42e-3)" "unprognostic (9.79e-2)" "unprognostic (3.91e-2)" "unprognostic (1.94e-3)" "unprognostic (1.12e-2)" "unprognostic (4.11e-1)" "unprognostic (1.25e-2)" "unprognostic (6.63e-2)" "unprognostic (4.51e-1)" "unprognostic (7.56e-3)" "unprognostic (6.13e-2)" 28.7 26.7 25.2 31.0 29.4 49.3 40.9 27.3 28.0 35.0 26.1 57.3 54.0 35.6 37.6 45.0 36.2 30.3 41.7 23.6 27.1 47.0 66.3 39.2 39.9 27.7 28.3 30.6 39.3 41.7 25.5 34.1 28.2 35.8 61.2 27.4 42.4 36.1 46.2 47.2 56.7 36.3 26.8 36.9 42.6 57.9 27.4 54.7 48.7 54.9 49.5 35.6 36.7 32.8 41.1 24.7 42.1 44.9 48.4 47.1 57.5 31.9 52.2 44.8 56.1 25.2 44.8 56.3 40.5 43.7 46.9 42.0 46.6 47.8 56.3 64.4 33.4 73.7 28.9 39.2 66.7 74.2 65.1 34.6 102.0 35.3 99.4 60.2 57.7 71.0 63.7 48.7 51.6 22.0 66.2 65.8 60.4 54.8 27.7 43.0 55.1 41.9 51.5 40.2 51.9 34.7 52.6 76.6 83.5 81.6 35.1 86.2 49.8 32.0 33.6 35.2 48.9 47.2 46.9 41.3 34.0 60.6 34.5 24.0 21.6 40.3 21.6 27.3 22.9 16.5 20.9 21.1 23.0 14.1 22.6 22.4 22.6 26.6 30.6 13.1 26.4 21.1 25.2 29.4 27.3 28.0 23.6 27.1 27.7 28.3 28.2 26.8 27.4 32.8 43.3 60.9 24.4 54.5 45.1 64.9 41.2 28.3 59.2 23.5 51.3 33.5 46.9 41.5 34.3 60.7 35.5 26.2 47.5 96.8 50.9 33.0 23.4 38.1 32.2 38.6 38.3 62.1 48.5 38.9 33.7 25.4 44.9 47.5 59.6 24.3 37.5 81.3 25.0 37.0 49.0 67.2 32.6 49.9 51.6 17.6 20.5 46.1 23.2 70.3 41.3 18.2 45.3 50.8 93.8 51.2 57.0 21.4 36.6 62.8 75.5 58.7 33.0 32.9 19.7 22.4 42.0 78.9 75.3 71.7 67.8 45.4 47.1 27.7 68.6 78.2 GUCA1C GCAP3 ENSG00000138472 "Guanylate cyclase activator 1C" O95843 3 108907792-108953879 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "retina: 296.7" "Cell type enriched" "Detected in some" 4 "Cone photoreceptor cells: 125.1" "Cancer enriched" "Detected in single" 7 "pancreatic cancer: 0.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 85 "RPTEC TERT1: 14.0" HPA041597 Uncertain Approved "Focal adhesion sites" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 9: Photoreceptor cells - Phototransduction" "Focal adhesion sites" "HPA041597: AB_10795501" "unprognostic (7.56e-2)" "unprognostic (6.56e-2)" 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.3 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.5 1.0 0.8 0.8 0.0 0.0 0.0 0.0 0.0 0.4 41.5 0.0 0.4 0.0 0.1 0.0 0.0 296.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 1.3 0.1 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.3 1.0 0.8 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 14.5 0.0 0.0 0.0 125.1 0.0 0.0 0.0 0.0 0.0 11.5 0.0 0.0 0.3 0.0 0.0 0.7 0.6 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.5 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 1.0 0.0 9.7 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 29.6 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.0 17.5 0.0 0.0 HENMT1 "C1orf59, FLJ30525, HEN1" ENSG00000162639 "HEN methyltransferase 1" Q5T8I9 1 108648290-108661526 "Enzymes, Predicted intracellular proteins" "RNA-mediated gene silencing" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 72.0" "Group enriched" "Detected in many" 4 "NK-cells: 58.7;Spermatocytes: 178.5;Spermatogonia: 107.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "JURKAT: 71.4;MOLT-4: 68.2;NB-4: 75.3;U-937: 98.6" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 19 "cerebellum: 9.1" "HPA028464, HPA028497" Uncertain Approved "Plasma membrane,Focal adhesion sites" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 32: U-937 - Innate immune response" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Plasma membrane, Focal adhesion sites" "HPA028464: AB_10600103, HPA028497: AB_10601552" "unprognostic (1.82e-1)" "prognostic favorable (2.56e-4)" "prognostic favorable (9.95e-4)" "unprognostic (2.92e-3)" "unprognostic (1.91e-1)" "unprognostic (3.88e-3)" "unprognostic (2.01e-2)" "unprognostic (1.49e-1)" "unprognostic (7.01e-2)" "unprognostic (1.25e-1)" "unprognostic (2.95e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.48e-5)" "unprognostic (2.53e-1)" "unprognostic (2.43e-1)" "unprognostic (2.18e-1)" "unprognostic (1.65e-1)" 5.4 2.9 8.6 8.0 8.9 13.3 8.0 6.8 9.2 8.5 4.9 6.5 5.0 3.9 4.7 2.7 2.3 6.5 1.8 8.9 9.6 3.4 2.0 4.7 13.5 8.0 8.1 5.2 2.1 0.9 5.3 5.6 8.9 3.7 9.5 3.0 3.0 3.4 3.2 3.8 7.6 3.6 7.8 11.1 4.7 72.0 10.6 18.7 2.2 6.2 11.3 6.2 2.0 8.6 16.9 8.5 0.7 0.0 0.7 0.5 0.1 4.0 1.5 9.4 1.5 24.7 26.0 0.0 8.9 7.5 0.0 0.1 0.0 0.2 5.9 5.5 0.0 42.4 31.7 0.0 8.1 25.4 36.4 7.8 0.5 2.1 0.0 0.0 1.9 71.4 0.0 18.5 0.4 42.8 68.2 75.3 24.0 13.5 3.7 29.3 0.0 1.5 0.0 18.0 40.1 0.0 35.3 9.8 0.1 2.4 0.0 55.7 0.5 0.0 31.4 17.5 0.1 11.2 15.0 0.1 0.0 98.6 0.3 43.3 19.7 43.2 61.8 24.0 55.6 12.6 30.0 56.4 24.6 7.1 24.7 45.1 19.6 55.6 29.8 19.5 31.2 39.9 8.6 8.9 6.8 9.2 8.9 9.6 8.0 8.1 8.9 7.8 10.6 8.6 2.4 0.0 1.1 2.3 5.4 1.7 1.4 6.6 1.2 5.2 8.1 7.1 1.8 14.3 4.0 5.5 0.0 12.8 28.0 4.0 3.9 3.0 12.2 2.2 3.6 3.0 4.9 13.9 5.2 1.3 21.5 5.2 2.6 2.4 7.0 2.9 6.1 0.5 15.8 0.0 3.7 4.0 4.1 11.7 3.3 20.1 5.0 7.5 1.8 3.7 11.2 3.6 58.7 4.0 2.7 2.8 7.4 3.0 8.0 1.2 5.5 0.8 2.8 2.4 6.6 3.0 3.5 178.5 107.7 2.9 1.6 5.2 23.0 8.5 6.1 3.3 HSH2D "ALX, FLJ14886, HSH2" ENSG00000196684 "Hematopoietic SH2 domain containing" Q96JZ2 19 16134028-16158575 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 47.0;lymphoid tissue: 37.7" "Cell type enhanced" "Detected in many" "B-cells: 78.5;dendritic cells: 101.3;Gastric mucus-secreting cells: 40.2;NK-cells: 82.4;Plasma cells: 134.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "basophil: 232.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 41.0;HL-60: 43.5;HMC-1: 56.4;NB-4: 140.1;RPMI-8226: 63.2;U-266/84: 41.9;U-937: 137.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036616 Approved "Plasma membrane,Focal adhesion sites,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Focal adhesion sites, Cytosol" "HPA036616: AB_10671962" "unprognostic (1.69e-1)" "unprognostic (2.97e-2)" "prognostic unfavorable (9.46e-6)" "unprognostic (1.06e-1)" "unprognostic (5.50e-3)" "unprognostic (5.21e-3)" "unprognostic (9.35e-2)" "unprognostic (4.78e-2)" "unprognostic (4.21e-3)" "unprognostic (9.96e-2)" "unprognostic (1.57e-2)" "unprognostic (2.22e-2)" "prognostic unfavorable (6.49e-6)" "unprognostic (9.17e-3)" "unprognostic (6.18e-2)" "unprognostic (3.21e-2)" "prognostic favorable (3.47e-5)" 1.6 0.7 0.5 16.8 1.1 47.0 3.3 1.1 1.1 3.0 1.2 9.8 12.7 1.3 1.8 1.7 3.2 5.4 0.4 0.5 0.4 1.5 2.2 5.6 27.2 1.5 0.7 0.5 4.3 2.3 4.0 1.5 1.1 5.1 9.3 0.3 9.5 2.9 0.4 0.4 20.5 1.0 0.7 37.7 12.7 0.4 1.0 8.7 2.6 1.2 35.7 7.5 0.7 2.8 15.0 0.1 0.1 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.1 2.2 21.3 41.0 0.6 0.0 0.8 0.7 0.0 0.6 0.0 2.3 0.1 0.6 0.5 2.6 0.0 43.5 56.4 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.1 37.4 0.0 9.0 0.1 140.1 0.0 5.5 0.0 3.0 0.0 63.2 0.4 5.6 0.1 0.1 0.0 1.3 0.3 0.0 0.3 15.9 0.2 0.1 0.1 0.2 0.2 5.7 41.9 23.6 0.2 137.3 0.0 232.1 15.5 100.9 17.1 22.0 15.8 56.4 7.6 11.2 25.5 35.8 6.9 9.2 182.6 85.2 38.8 7.6 13.0 16.7 0.5 1.1 1.1 1.1 0.5 0.4 1.5 0.7 1.1 0.7 1.0 2.8 1.0 3.2 8.9 0.0 78.5 0.3 1.2 3.0 0.6 0.0 3.6 1.9 0.6 5.7 11.3 5.5 0.0 2.6 101.3 18.9 0.0 6.7 0.0 4.5 1.5 0.8 8.4 32.2 0.5 5.1 4.1 0.7 40.2 7.9 6.3 0.1 1.4 0.6 1.1 0.0 0.4 19.1 2.0 3.4 2.4 0.1 0.0 7.3 10.6 1.0 10.7 0.0 82.4 1.0 0.3 9.7 18.0 0.0 134.0 2.6 17.9 0.3 7.9 0.0 0.0 1.1 0.7 0.1 0.5 0.1 0.1 3.4 31.0 0.2 9.3 4.1 IGSF5 JAM4 ENSG00000183067 "Immunoglobulin superfamily member 5" Q9NSI5 21 39745407-39802096 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enriched" "Detected in some" 8 "Syncytiotrophoblasts: 114.1" "Cancer enhanced" "Detected in some" "testis cancer: 2.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "T-47d: 5.8" HPA057282 Uncertain Approved "Focal adhesion sites" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 6: T47d - Mammary gland" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Focal adhesion sites" "HPA057282: AB_2683395" "unprognostic (1.06e-1)" "unprognostic (2.53e-1)" "unprognostic (7.06e-2)" "unprognostic (9.73e-5)" "unprognostic (1.56e-2)" "unprognostic (3.15e-1)" "unprognostic (1.41e-1)" "unprognostic (2.18e-2)" "unprognostic (2.09e-1)" "unprognostic (8.35e-2)" "unprognostic (9.61e-2)" "unprognostic (4.01e-1)" "unprognostic (4.18e-1)" "unprognostic (3.75e-2)" "unprognostic (6.89e-2)" "unprognostic (1.07e-2)" 0.3 1.2 2.0 0.2 2.8 0.4 0.9 0.6 1.9 0.7 2.4 0.4 0.3 0.7 1.9 0.2 0.7 0.4 3.3 1.5 2.6 0.4 0.4 0.3 0.4 1.5 1.6 1.0 1.5 0.2 0.6 2.5 1.3 1.4 0.7 1.2 0.5 0.4 0.2 0.5 0.3 0.4 0.7 0.4 0.5 1.1 3.6 0.6 0.6 0.1 0.4 0.4 0.1 1.4 0.7 0.4 2.4 0.6 2.3 1.8 0.6 0.4 0.6 0.6 1.0 0.4 0.7 0.8 0.6 0.9 0.9 0.6 0.8 1.6 1.3 1.3 1.1 0.7 1.9 0.3 1.4 1.0 0.3 1.7 2.9 1.5 1.7 1.2 0.3 0.3 1.4 0.5 0.9 0.9 0.2 0.3 1.3 0.6 0.4 0.4 1.1 0.4 1.0 1.0 1.1 0.3 0.6 1.6 1.0 1.0 5.8 0.6 0.2 1.0 1.2 0.5 1.0 0.5 0.4 0.5 0.6 0.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.0 2.8 0.6 1.9 1.5 2.6 1.5 1.6 1.3 0.7 3.6 1.4 0.0 0.0 0.0 8.5 0.0 0.0 0.2 0.0 0.0 1.2 1.0 0.8 9.7 0.0 0.1 1.8 0.0 1.6 0.0 0.6 5.9 0.6 12.8 0.0 0.4 0.2 0.0 0.0 2.9 0.2 1.7 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.4 0.0 4.1 0.4 0.0 0.0 0.0 4.8 0.3 0.1 0.0 0.0 0.0 1.0 0.0 5.0 1.0 0.2 0.2 0.4 0.0 1.4 0.0 6.8 0.1 0.2 0.0 0.0 0.2 0.5 0.2 0.0 0.0 114.1 0.1 1.1 0.4 2.0 IL1RL1 "DER4, FIT-1, IL33R, ST2, ST2L, ST2V, T1" ENSG00000115602 "Interleukin 1 receptor like 1" Q01638 2 102311502-102352037 "Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 126.4;lung: 162.0;placenta: 199.8" "Cell type enriched" "Detected in many" 9 "granulocytes: 501.5" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 7.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 64 "basophil: 38.3;eosinophil: 29.3" "Lineage enriched" "Detected in single" 72 "granulocytes: 38.3" "Group enriched" "Detected in some" 6 "HHSteC: 245.1;HMC-1: 373.7;HUVEC TERT2: 185.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA007406, HPA007917" Uncertain Supported "Plasma membrane,Focal adhesion sites,Cytosol" "Secreted to blood" NA NA 19100000 3100000 "Cluster 2: Granulocytes - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Plasma membrane" "Focal adhesion sites, Cytosol" "HPA007406: AB_1079128, HPA007917: AB_1079129" "unprognostic (7.25e-2)" "unprognostic (9.72e-2)" "unprognostic (1.44e-1)" "unprognostic (3.28e-2)" "unprognostic (5.28e-2)" "unprognostic (1.98e-2)" "unprognostic (3.25e-3)" "unprognostic (2.07e-1)" "unprognostic (2.77e-1)" "unprognostic (4.50e-2)" "unprognostic (8.58e-2)" "unprognostic (9.74e-2)" "unprognostic (1.44e-1)" "unprognostic (1.32e-2)" "unprognostic (1.60e-2)" "unprognostic (1.17e-1)" "unprognostic (4.60e-3)" 22.3 30.3 7.5 3.1 9.8 0.7 14.7 7.8 11.0 3.6 12.2 5.2 1.7 2.5 0.6 4.4 2.6 14.7 24.7 7.2 8.2 126.4 16.0 162.0 0.7 7.6 7.7 1.1 4.8 0.8 5.7 199.8 7.7 4.9 3.4 2.8 1.8 4.6 2.5 4.3 8.0 3.7 8.0 1.4 25.1 0.5 9.6 1.3 4.1 0.7 0.8 6.5 3.9 8.9 0.9 0.2 0.7 0.1 15.1 0.6 0.3 0.5 0.7 0.4 0.6 0.3 0.5 0.5 0.7 0.2 0.2 1.4 0.2 6.3 0.4 0.2 0.1 45.7 0.8 0.8 245.1 1.9 373.7 5.1 1.5 6.2 40.0 0.6 185.5 0.2 0.9 0.8 0.7 0.4 0.6 8.7 0.3 0.4 0.7 0.3 0.2 0.2 1.0 0.3 0.6 0.4 0.5 0.3 0.2 0.4 0.3 0.1 15.4 0.5 0.5 3.5 0.5 0.1 0.3 0.4 0.7 0.6 0.5 38.3 0.0 29.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 7.5 9.8 7.8 11.0 7.2 8.2 7.6 7.7 7.7 8.0 9.6 8.9 22.6 9.6 13.1 0.0 0.1 8.5 20.3 0.4 0.0 0.0 0.3 0.1 2.7 0.0 7.7 1.8 0.0 0.0 3.3 0.1 0.0 3.2 0.4 1.1 14.8 49.7 0.0 1.3 0.2 0.5 0.1 54.5 0.0 2.5 501.5 0.0 26.4 0.7 0.0 0.0 0.2 0.0 0.0 0.3 19.1 1.3 0.9 3.0 3.6 0.0 0.0 0.0 0.0 0.5 0.1 37.2 0.0 0.0 3.2 15.7 0.0 0.0 6.6 0.3 39.5 1.5 37.7 0.0 0.0 0.0 5.1 0.0 31.5 0.0 0.0 16.4 ILK ENSG00000166333 "Integrin linked kinase" Q13418 11 6603708-6610874 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004041, HPA048437" Enhanced Supported "Nucleoplasm,Plasma membrane,Focal adhesion sites" NA NA 30000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane, Focal adhesion sites" Nucleoplasm "CAB004041: AB_2127050, HPA048437: AB_2680391" "unprognostic (1.78e-1)" "unprognostic (2.26e-2)" "unprognostic (5.26e-2)" "unprognostic (2.12e-2)" "unprognostic (7.57e-2)" "unprognostic (1.01e-1)" "unprognostic (6.19e-3)" "unprognostic (5.25e-3)" "unprognostic (1.49e-2)" "unprognostic (9.65e-2)" "unprognostic (2.64e-1)" "unprognostic (8.12e-2)" "prognostic favorable (2.44e-4)" "unprognostic (4.01e-3)" "unprognostic (9.27e-2)" "unprognostic (2.42e-1)" "unprognostic (6.36e-3)" 108.0 77.2 49.8 85.1 52.4 43.7 91.8 51.7 50.6 151.6 55.0 398.2 66.4 359.1 81.8 115.5 164.2 88.0 175.9 47.4 50.7 78.8 65.9 107.9 72.4 51.8 50.6 101.0 89.3 73.2 47.1 98.8 50.9 182.7 116.8 28.3 69.5 412.2 90.8 61.5 117.4 364.7 51.1 95.5 149.7 26.5 53.7 45.8 72.0 92.0 70.5 226.7 118.8 51.9 127.8 94.4 148.9 51.8 224.8 159.4 67.2 182.2 360.0 211.9 256.0 102.7 145.7 47.0 47.0 304.1 206.9 99.5 84.4 155.6 213.0 83.5 74.3 69.1 84.9 82.8 150.8 55.9 74.7 153.2 72.8 143.8 108.9 217.7 206.9 40.5 63.7 55.0 282.8 97.1 49.4 97.4 94.3 107.5 110.8 51.0 77.8 50.5 160.3 100.8 25.6 57.4 86.0 118.4 103.6 144.0 82.2 62.2 238.8 263.9 118.0 111.1 90.7 38.9 25.9 67.1 195.6 82.8 125.3 314.9 260.0 417.6 127.3 258.1 124.9 96.9 114.4 122.3 242.7 92.9 70.2 88.5 165.5 257.8 254.8 98.5 142.8 402.8 49.8 52.4 51.7 50.6 47.4 50.7 51.8 50.6 50.9 51.1 53.7 51.9 79.5 44.8 17.9 24.2 33.6 50.5 73.7 100.6 24.5 21.5 43.1 68.2 0.5 70.1 49.7 57.0 8.4 119.8 46.0 71.9 58.7 136.1 64.6 33.2 78.1 69.4 37.9 53.7 14.6 125.0 177.7 83.2 50.4 52.5 30.4 41.6 76.4 31.4 127.4 8.4 17.1 50.1 69.2 51.5 97.7 143.7 71.4 115.9 85.4 30.9 143.0 54.3 77.2 15.6 15.3 117.1 60.0 147.4 35.1 42.0 74.5 98.6 31.0 32.9 157.8 53.3 165.8 31.7 17.1 32.3 43.2 110.0 49.3 65.0 50.1 43.9 INPP5E "CORS1, JBTS1, pharbin, PPI5PIV" ENSG00000148384 "Inositol polyphosphate-5-phosphatase E" Q9NRR6 9 136428619-136439845 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Ciliopathy, Disease variant, Joubert syndrome, Mental retardation, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065758 Approved Approved "Golgi apparatus,Focal adhesion sites" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" "Golgi apparatus, Focal adhesion sites" "HPA065758: AB_2685554" "unprognostic (1.99e-1)" "unprognostic (8.68e-2)" "unprognostic (1.87e-2)" "unprognostic (1.23e-2)" "unprognostic (4.00e-1)" "unprognostic (6.92e-2)" "unprognostic (9.60e-3)" "unprognostic (3.21e-1)" "unprognostic (5.81e-2)" "unprognostic (2.65e-2)" "prognostic favorable (1.82e-4)" "unprognostic (2.03e-1)" "unprognostic (3.04e-2)" "unprognostic (3.76e-1)" "unprognostic (5.48e-2)" "unprognostic (4.64e-1)" "unprognostic (2.66e-2)" 12.1 10.8 15.0 6.9 15.0 6.4 11.7 15.3 19.9 15.1 11.3 13.1 5.7 15.2 2.3 10.6 17.6 5.3 13.7 14.0 14.3 13.3 12.2 11.9 8.2 15.1 13.3 16.2 10.8 6.6 14.3 5.7 15.5 12.3 3.3 7.4 9.5 5.3 8.5 11.2 11.7 5.6 11.4 20.8 8.9 20.1 14.8 6.4 15.1 3.8 4.7 12.2 12.0 13.9 8.9 10.3 12.6 13.2 6.5 7.1 14.9 10.7 5.7 7.4 5.1 12.5 6.0 10.8 10.5 11.1 11.9 25.2 6.2 8.6 2.8 36.8 25.4 8.5 27.1 8.4 10.3 9.5 11.9 10.9 8.8 9.8 7.2 10.3 8.9 14.8 14.5 14.0 7.0 22.3 11.4 19.9 8.1 5.3 16.0 21.1 8.7 8.3 7.4 9.8 14.1 12.2 10.4 8.5 7.6 7.6 15.1 15.6 11.8 24.1 9.4 10.1 18.2 11.6 10.6 4.5 12.0 7.8 9.7 0.0 0.1 0.5 0.5 0.0 0.3 0.7 0.6 0.4 0.1 0.4 0.2 0.4 0.1 0.0 0.0 0.2 0.7 0.1 15.0 15.0 15.3 19.9 14.0 14.3 15.1 13.3 15.5 11.4 14.8 13.9 14.7 3.2 6.9 17.0 5.0 5.5 1.8 2.6 5.7 7.4 6.5 6.9 5.0 7.2 3.4 3.7 2.1 2.3 7.6 4.0 1.9 4.8 0.9 11.8 8.1 7.4 6.1 0.8 12.2 5.6 2.8 5.7 3.6 6.8 8.9 8.3 6.1 3.8 3.2 15.2 12.9 2.6 6.1 3.5 3.5 1.3 7.5 3.7 5.4 6.5 3.5 8.9 1.0 8.5 8.5 6.7 1.6 5.7 2.5 3.3 3.4 2.4 10.0 10.8 0.0 5.5 7.5 15.3 9.1 5.4 4.8 0.8 5.3 5.6 3.9 1.6 ITGAV "CD51, MSK8, VNRA, VTNR" ENSG00000138448 "Integrin subunit alpha V" P06756 2 186590056-186680901 "Cancer-related genes, CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "basophil: 6.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 6.2" "Cell line enhanced" "Detected in many" "RT4: 369.7;SuSa: 297.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002499, HPA004856" Supported Approved "Focal adhesion sites,Cytosol" NA NA 2000000 "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "Focal adhesion sites, Cytosol" "CAB002499: AB_563594, HPA004856: AB_1846316" "unprognostic (4.03e-2)" "unprognostic (5.17e-3)" "unprognostic (1.22e-2)" "unprognostic (5.22e-2)" "unprognostic (1.33e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (2.08e-4)" "unprognostic (1.48e-2)" "unprognostic (6.95e-2)" "unprognostic (2.89e-1)" "prognostic unfavorable (5.07e-4)" "unprognostic (5.84e-2)" "unprognostic (2.67e-2)" "prognostic unfavorable (1.05e-6)" "unprognostic (2.61e-1)" "unprognostic (9.11e-2)" "unprognostic (8.07e-2)" 39.9 38.7 20.1 36.5 30.8 6.4 27.7 39.7 23.5 39.7 40.3 20.1 15.9 36.8 10.5 24.5 26.3 47.3 80.0 18.2 32.7 52.1 18.0 25.7 15.8 42.5 33.0 64.7 25.7 82.7 11.9 47.4 46.4 29.8 21.6 80.4 32.1 28.1 16.3 41.4 16.3 56.7 45.3 21.4 34.2 14.7 30.2 18.0 62.6 30.5 21.6 43.1 16.0 54.6 49.1 57.5 37.4 119.9 134.1 90.0 141.7 93.8 75.5 32.5 32.5 50.7 164.0 0.4 179.7 106.3 113.4 60.2 19.3 88.5 46.7 9.7 17.2 11.7 69.1 69.6 52.8 8.3 7.0 65.8 41.3 72.7 61.1 194.1 78.7 5.9 11.6 23.9 87.4 19.4 5.0 6.8 28.3 29.1 28.5 0.1 76.2 6.8 83.5 369.7 7.7 23.0 108.6 33.2 40.1 297.0 26.2 22.4 240.5 199.4 61.9 41.4 80.3 5.9 10.4 5.5 80.3 3.3 100.6 6.2 0.6 0.9 0.4 1.1 0.3 0.1 0.2 0.4 0.4 0.0 0.2 0.2 0.2 0.2 0.6 0.2 0.6 0.2 20.1 30.8 39.7 23.5 18.2 32.7 42.5 33.0 46.4 45.3 30.2 54.6 39.8 28.9 22.9 134.8 4.9 128.4 64.0 127.7 42.7 118.4 50.4 23.4 145.5 80.1 35.3 77.3 77.2 55.1 9.4 32.4 1.9 78.7 0.6 61.7 61.1 47.2 7.3 2.1 36.3 101.8 26.9 65.4 57.6 100.2 49.5 21.2 27.8 18.2 27.6 15.2 35.9 19.9 14.2 44.3 56.7 3.1 19.3 29.3 46.2 75.9 17.4 70.9 2.1 184.5 156.1 165.9 23.8 25.9 9.2 103.4 11.2 32.4 27.0 60.2 32.9 29.0 63.3 1.7 2.4 27.7 103.7 39.7 10.9 18.1 15.5 77.7 ITGB1 "CD29, FNRB, GPIIA, MDF2, MSK12" ENSG00000150093 "Integrin subunit beta 1" P05556 10 32887273-33005792 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ductal cells: 1206.9;Pancreatic endocrine cells: 1393.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-RPE1: 2711.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003434, HPA059297, HPA069003" Enhanced Supported "Endoplasmic reticulum,Plasma membrane,Focal adhesion sites" NA NA 270000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Focal adhesion sites" "Endoplasmic reticulum" "CAB003434: AB_303570, HPA059297: AB_2732634, HPA069003: AB_2732125" "unprognostic (3.07e-2)" "prognostic unfavorable (5.01e-4)" "unprognostic (8.67e-2)" "unprognostic (4.36e-1)" "unprognostic (1.20e-2)" "unprognostic (3.87e-2)" "unprognostic (1.60e-2)" "prognostic unfavorable (3.36e-6)" "unprognostic (3.22e-1)" "unprognostic (2.36e-3)" "unprognostic (3.68e-3)" "unprognostic (2.42e-1)" "unprognostic (1.02e-3)" "unprognostic (1.25e-2)" "unprognostic (2.23e-1)" "unprognostic (2.48e-1)" "unprognostic (3.08e-2)" 491.9 179.3 61.5 241.5 78.2 81.5 216.2 75.0 90.9 259.2 68.3 265.3 147.4 330.4 171.7 168.6 172.0 347.4 390.3 60.2 74.3 180.4 287.1 233.6 118.0 88.4 80.6 157.1 135.3 145.4 59.8 459.5 88.9 248.1 223.6 27.7 130.7 427.7 157.9 92.2 150.8 710.0 76.6 204.7 160.1 91.2 86.4 77.5 161.5 194.5 106.2 357.4 119.1 88.9 638.0 907.0 495.4 559.6 1183.4 1019.5 398.1 2063.9 1239.6 999.0 903.9 215.9 1478.2 164.5 354.1 1830.9 638.0 438.9 149.1 1204.1 1122.0 163.1 112.7 195.8 416.3 253.6 826.4 48.3 195.5 1027.7 658.2 1040.8 426.0 2711.1 1263.6 81.0 136.6 76.5 1700.8 109.0 80.1 46.7 107.4 200.6 428.2 52.0 357.0 30.9 1454.8 186.2 108.0 271.4 649.9 114.6 498.2 813.7 153.9 175.0 1362.6 1280.0 712.2 904.2 719.7 64.7 14.8 91.2 956.6 198.2 518.5 7.5 35.1 16.1 83.4 69.8 22.8 109.6 191.8 138.7 33.9 40.3 24.9 68.4 9.0 90.3 108.2 11.4 266.8 117.2 61.5 78.2 75.0 90.9 60.2 74.3 88.4 80.6 88.9 76.6 86.4 88.9 631.5 342.9 143.8 26.4 118.0 546.7 435.5 531.6 208.3 32.8 147.1 307.5 210.8 241.6 268.1 226.2 31.3 210.3 217.8 179.8 13.7 1206.9 6.6 194.6 437.9 421.1 193.3 153.0 37.2 411.3 515.2 374.7 95.8 406.5 88.7 561.8 375.9 268.1 179.8 38.7 52.4 97.4 213.6 170.1 206.7 18.3 254.5 217.8 343.3 67.5 119.4 72.0 111.2 42.7 66.8 1393.7 128.5 601.8 181.2 412.5 75.6 68.7 171.5 45.5 637.7 236.3 724.0 10.1 76.0 84.4 170.5 219.7 211.3 225.6 127.0 296.1 JAK2 JTK10 ENSG00000096968 "Janus kinase 2" O60674 9 4984390-5129948 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Chromatin regulator, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 93.4;Inhibitory neurons: 122.3;Microglial cells: 106.8;Oligodendrocyte precursor cells: 69.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 132.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 132.5" "Group enriched" "Detected in many" 5 "ASC diff: 42.2;HDLM-2: 75.0;HEL: 154.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013089, HPA040820, HPA043870" Approved Supported "Nucleoplasm,Plasma membrane,Focal adhesion sites" No No "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Plasma membrane, Focal adhesion sites" "CAB013089: AB_2533647, HPA040820: AB_2677151, HPA043870: AB_2678708" "unprognostic (2.24e-3)" "unprognostic (2.76e-2)" "unprognostic (1.50e-2)" "unprognostic (7.67e-2)" "unprognostic (5.50e-2)" "unprognostic (3.09e-2)" "unprognostic (1.48e-1)" "unprognostic (7.36e-2)" "unprognostic (1.09e-1)" "unprognostic (5.49e-3)" "unprognostic (1.58e-1)" "unprognostic (1.72e-2)" "unprognostic (3.85e-1)" "unprognostic (4.53e-2)" "unprognostic (3.43e-2)" "unprognostic (1.96e-1)" "unprognostic (7.37e-3)" 15.6 7.6 3.2 19.2 3.7 21.7 8.9 6.3 9.1 8.5 1.1 6.7 6.5 11.3 8.6 8.8 8.0 10.5 24.5 2.7 3.1 6.8 4.5 10.9 18.2 3.3 1.8 11.5 3.8 6.5 2.9 11.0 2.0 6.8 6.5 12.8 4.0 6.2 9.8 11.2 7.7 9.5 3.5 17.6 13.4 9.8 1.7 7.5 4.8 8.9 12.7 11.7 9.1 3.9 6.8 3.7 3.7 6.3 42.2 12.4 1.1 9.1 8.6 7.2 4.6 1.2 2.0 0.3 2.1 5.4 5.4 2.3 4.4 5.1 4.9 75.0 1.4 154.7 7.6 1.7 10.0 10.5 7.1 9.5 2.1 2.8 4.5 7.6 6.6 5.1 10.9 17.4 11.6 2.2 2.9 12.8 3.3 3.3 4.3 5.1 8.2 2.2 4.7 3.5 4.2 2.4 2.6 3.5 2.8 3.6 2.0 15.4 13.1 10.2 3.6 10.7 6.4 3.1 6.4 1.5 13.6 4.7 5.3 132.5 20.5 38.2 5.6 20.1 4.5 5.6 4.1 3.1 26.5 4.9 2.2 2.8 19.2 9.6 16.4 9.7 4.5 7.7 3.2 3.7 6.3 9.1 2.7 3.1 3.3 1.8 2.0 3.5 1.7 3.9 14.3 16.0 7.9 31.6 12.9 9.7 3.3 4.9 10.8 8.0 5.2 3.4 30.0 0.0 6.7 7.3 8.4 1.9 13.9 11.7 1.9 3.3 8.6 5.1 11.2 9.4 3.0 19.8 93.4 3.9 0.9 8.9 38.7 5.6 14.0 11.4 4.6 1.9 14.2 8.4 122.3 4.5 0.0 33.6 28.8 7.1 23.6 38.9 5.4 106.8 49.5 12.6 8.2 69.9 42.3 7.0 20.9 33.4 10.7 3.0 3.9 3.3 7.1 11.2 0.0 9.7 12.5 15.0 5.5 11.6 8.4 3.4 10.4 5.1 4.1 4.5 KLF11 "MODY7, TIEG2, Tieg3" ENSG00000172059 "Kruppel like factor 11" O14901 2 10042849-10054836 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 135.0;Suprabasal keratinocytes: 86.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 47.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058276 Supported "Nucleoplasm,Nuclear bodies,Focal adhesion sites,Cytosol" Yes No "Cluster 7: Monocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "Nuclear bodies, Focal adhesion sites, Cytosol" "HPA058276: AB_2683664" "unprognostic (9.66e-3)" "unprognostic (1.87e-1)" "unprognostic (1.59e-1)" "unprognostic (1.06e-2)" "unprognostic (3.02e-3)" "unprognostic (2.63e-3)" "unprognostic (6.34e-2)" "unprognostic (1.04e-2)" "unprognostic (1.67e-1)" "unprognostic (1.04e-1)" "unprognostic (3.17e-3)" "unprognostic (3.08e-2)" "unprognostic (2.48e-3)" "unprognostic (8.96e-2)" "unprognostic (3.44e-1)" "unprognostic (1.07e-2)" "unprognostic (9.24e-2)" 27.7 15.6 4.0 7.6 3.2 27.8 22.3 8.3 3.9 13.5 4.1 17.9 7.5 20.0 9.7 13.2 13.7 18.1 19.1 2.9 3.9 15.7 35.2 22.4 9.3 3.7 3.3 23.9 54.2 18.3 2.5 19.5 3.4 10.1 9.3 3.0 15.9 14.8 12.1 26.9 8.7 16.8 3.2 18.8 12.4 30.0 3.5 4.0 16.5 27.3 5.5 12.6 13.1 5.1 6.9 3.3 7.8 0.7 5.3 9.4 18.8 7.9 7.9 4.4 4.6 7.8 15.8 0.0 13.9 9.6 17.9 1.6 6.8 6.1 2.9 47.6 5.2 3.5 9.7 1.6 5.2 14.6 22.1 14.7 22.3 8.4 2.3 11.4 3.9 1.3 9.7 30.8 4.6 8.2 0.0 2.7 12.5 5.6 6.7 7.8 0.2 13.6 10.8 8.5 10.0 6.2 12.0 24.5 23.4 12.2 5.7 19.6 11.2 19.3 15.9 14.7 2.6 27.9 36.0 18.7 5.0 3.8 10.4 0.0 8.2 2.0 2.6 12.3 0.8 3.2 1.8 1.9 7.3 2.9 0.5 1.1 0.2 6.6 14.8 0.3 3.0 5.4 4.0 3.2 8.3 3.9 2.9 3.9 3.7 3.3 3.4 3.2 3.5 5.1 58.8 6.4 4.6 0.3 12.5 60.5 17.7 5.5 25.6 6.2 14.3 13.2 3.5 10.0 6.1 7.3 6.2 3.2 10.1 2.5 29.4 8.2 135.0 9.1 21.5 33.3 7.1 4.6 1.7 8.5 4.2 17.5 9.7 26.6 8.2 15.5 37.5 38.1 12.5 3.3 1.4 7.0 16.2 32.4 42.4 25.9 14.6 22.0 30.2 1.0 16.6 2.2 3.1 0.5 0.3 8.9 1.5 16.6 5.3 15.0 6.1 8.4 4.3 5.8 32.9 10.4 35.7 13.8 39.0 13.1 86.2 8.2 10.8 11.2 7.8 11.7 LASP1 "Lasp-1, MLN50" ENSG00000002834 "LIM and SH3 protein 1" Q14847 17 38869859-38921770 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Ion transport, Transport" Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 591.7;Proximal enterocytes: 292.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012072, CAB022049" Enhanced Supported "Plasma membrane,Focal adhesion sites,Cytosol" NA NA 9400000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane, Cytosol" "Focal adhesion sites" "CAB022049: , HPA012072: AB_1852714" "unprognostic (1.23e-1)" "unprognostic (2.09e-2)" "unprognostic (1.77e-1)" "prognostic unfavorable (4.57e-4)" "unprognostic (1.47e-1)" "unprognostic (3.03e-2)" "prognostic unfavorable (2.41e-4)" "unprognostic (1.06e-3)" "unprognostic (2.24e-1)" "unprognostic (9.60e-2)" "unprognostic (9.87e-3)" "unprognostic (1.01e-1)" "unprognostic (9.65e-3)" "unprognostic (1.29e-3)" "unprognostic (3.95e-2)" "unprognostic (1.60e-3)" "unprognostic (4.53e-2)" 86.4 38.0 60.8 75.9 56.7 126.4 55.5 45.5 56.7 46.9 48.6 93.0 131.9 43.8 32.3 45.9 46.0 56.8 40.3 56.1 61.0 55.9 76.4 68.6 76.1 56.2 63.5 48.5 59.0 25.5 33.0 81.4 59.0 30.9 92.3 26.8 44.8 33.9 23.7 44.4 168.8 51.2 52.9 74.3 96.2 23.9 67.4 74.1 34.9 27.7 78.2 53.2 37.3 50.1 214.1 441.0 124.1 111.0 182.8 196.9 218.7 267.8 257.8 274.5 198.5 134.3 225.8 98.8 214.1 417.3 154.9 332.4 58.5 204.1 239.6 71.6 31.6 47.5 124.2 235.8 173.0 110.4 134.1 176.3 69.6 234.6 66.1 170.7 188.0 59.0 81.9 30.3 389.4 72.0 127.1 163.6 63.0 189.9 109.4 70.7 67.6 123.8 332.7 187.9 19.0 45.4 159.3 160.5 134.7 233.5 255.7 128.2 331.4 160.0 233.0 189.7 162.0 79.7 115.8 75.2 170.2 96.7 197.2 21.8 31.4 35.0 30.7 33.1 20.3 11.7 15.2 20.4 27.3 10.8 12.7 19.8 67.0 34.2 42.1 20.5 21.4 32.5 60.8 56.7 45.5 56.7 56.1 61.0 56.2 63.5 59.0 52.9 67.4 50.1 54.5 41.7 27.6 17.6 41.8 41.8 21.5 26.0 51.8 66.4 82.4 43.2 1.1 55.8 30.4 73.5 10.4 7.5 69.5 225.2 17.6 65.7 89.6 27.5 31.7 54.3 86.5 21.0 16.4 76.5 59.1 50.1 119.3 46.4 52.0 37.4 64.6 115.4 83.9 26.9 16.0 101.9 28.5 127.7 73.0 591.7 51.9 71.9 35.6 24.4 94.3 22.2 164.8 11.1 4.4 111.0 116.4 39.9 32.8 24.2 292.7 72.9 57.3 23.1 65.7 65.4 53.4 2.9 5.7 62.2 28.4 6.4 63.4 19.2 97.8 31.8 LDB3 "CMD1C, KIAA0613, PDLIM6, ZASP" ENSG00000122367 "LIM domain binding 3" O75112 10 86668507-86736072 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cardiomyopathy, Disease variant, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 26 "heart muscle: 1423.0;skeletal muscle: 2945.6;tongue: 1809.4" "Cell type enriched" "Detected in many" 7 "Cardiomyocytes: 1825.0" "Group enriched" "Detected in some" 4 "head and neck cancer: 1.7;melanoma: 2.5;prostate cancer: 3.6;stomach cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HSkMC: 3.0;hTERT-RPE1: 3.3;SCLC-21H: 4.9;SK-MEL-30: 2.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048955 Enhanced Supported "Nucleoplasm,Focal adhesion sites,Cytosol" NA NA 750000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 54: Cardiomyocytes - Muscle contraction" "Focal adhesion sites, Cytosol" Nucleoplasm "HPA048955: AB_2680568" "unprognostic (1.60e-1)" "unprognostic (9.01e-2)" "unprognostic (4.87e-2)" "unprognostic (6.92e-2)" "unprognostic (5.55e-2)" "unprognostic (1.50e-2)" "unprognostic (2.57e-2)" "unprognostic (1.36e-1)" "unprognostic (2.79e-2)" "unprognostic (7.61e-2)" "unprognostic (2.54e-3)" "unprognostic (3.55e-2)" "unprognostic (4.72e-4)" "unprognostic (3.07e-2)" "unprognostic (1.60e-1)" "unprognostic (1.62e-2)" "unprognostic (3.16e-1)" 11.1 1.4 12.8 2.8 39.6 0.4 6.5 29.8 29.0 10.1 0.1 36.2 2.4 15.1 4.9 54.5 17.3 3.1 1423.0 14.7 23.3 2.0 0.8 5.1 0.5 55.5 36.9 6.4 1.3 0.5 2.4 2.7 46.2 38.1 5.3 0.7 20.8 25.2 2945.6 4.8 8.8 23.7 26.4 0.6 9.0 4.7 38.4 0.7 5.2 1809.4 0.3 7.0 10.3 78.4 0.1 0.1 0.2 1.7 0.2 0.0 0.2 0.2 0.1 0.0 0.1 0.1 0.2 0.1 0.3 0.0 0.3 0.2 0.0 0.0 0.0 0.5 0.4 0.4 0.7 0.0 0.0 0.0 0.9 3.0 0.2 0.0 0.0 3.3 0.0 0.3 0.1 1.0 0.0 0.8 0.2 0.1 0.2 0.2 0.2 0.0 1.1 0.0 0.0 0.6 4.9 0.9 0.2 0.1 2.4 0.7 0.2 0.1 0.0 0.1 0.2 0.2 0.0 0.1 0.3 0.2 0.4 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.8 39.6 29.8 29.0 14.7 23.3 55.5 36.9 46.2 26.4 38.4 78.4 1.5 0.0 0.0 1.0 0.0 1.0 0.5 0.2 0.0 1.5 0.2 0.3 1825.0 0.0 0.2 1.8 0.0 0.1 0.0 0.0 0.0 0.0 23.4 0.1 0.4 15.5 0.0 0.0 4.5 1.1 0.0 31.5 0.0 0.2 0.0 0.9 0.0 0.0 0.1 0.0 2.6 0.0 4.1 0.0 1.2 19.6 11.1 0.5 1.8 1.9 0.0 0.7 0.0 1.5 245.1 0.1 0.0 6.8 0.0 0.3 0.0 0.1 0.1 4.1 39.5 48.0 54.9 1.0 1.0 0.0 0.0 0.0 0.2 0.2 0.0 0.2 LIMA1 EPLIN ENSG00000050405 "LIM domain and actin binding 1" Q9UHB6 12 50175788-50283546 "Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 553.9;Basal prostatic cells: 646.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "fHDF/TERT166: 523.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023871, HPA052645" Enhanced Enhanced "Plasma membrane,Actin filaments,Focal adhesion sites,Cytosol" NA NA 90000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Actin filaments" "Focal adhesion sites, Cytosol" "HPA023871: AB_1852875, HPA052645: AB_2681898" "unprognostic (6.22e-2)" "unprognostic (9.39e-3)" "unprognostic (8.13e-2)" "unprognostic (1.42e-1)" "unprognostic (8.08e-2)" "prognostic unfavorable (1.76e-6)" "unprognostic (1.63e-1)" "unprognostic (2.29e-1)" "unprognostic (2.28e-2)" "unprognostic (2.65e-1)" "unprognostic (1.28e-3)" "unprognostic (6.27e-2)" "prognostic favorable (2.79e-4)" "unprognostic (7.12e-2)" "unprognostic (9.26e-3)" "unprognostic (1.46e-1)" "unprognostic (1.43e-1)" 122.2 47.1 11.9 39.9 13.6 4.2 89.4 40.3 16.4 63.3 12.3 125.6 112.1 56.8 33.2 37.1 47.9 69.3 31.9 11.7 13.1 48.7 20.7 62.5 32.6 15.4 13.8 38.6 31.1 31.0 24.0 50.6 17.3 45.7 130.5 32.2 47.2 42.2 21.9 47.3 121.8 48.6 13.3 40.8 96.8 16.2 13.1 38.1 33.3 28.3 33.8 96.7 53.2 16.3 154.3 4.5 47.2 69.7 211.9 211.0 177.7 377.2 264.4 296.9 235.8 57.7 220.2 6.8 34.1 523.4 99.7 170.8 42.8 348.7 258.1 98.1 45.1 64.2 16.2 20.5 135.3 23.2 87.5 142.2 100.8 104.6 297.8 89.0 106.2 28.3 45.6 30.3 96.9 26.5 29.0 7.1 24.3 81.0 20.5 28.7 115.2 2.4 68.7 180.3 35.2 75.4 51.5 102.7 166.6 50.0 49.0 14.1 166.7 126.5 98.0 118.4 62.1 16.5 2.0 28.0 137.6 25.3 55.6 0.2 0.2 1.5 6.6 1.1 2.6 0.2 8.2 8.1 4.9 0.6 3.3 6.0 0.1 5.9 2.7 1.2 15.3 3.0 11.9 13.6 40.3 16.4 11.7 13.1 15.4 13.8 17.3 13.3 13.1 16.3 123.2 44.8 91.2 13.4 4.8 553.9 646.1 175.4 283.4 14.6 62.2 73.0 7.3 61.5 179.1 119.5 160.6 128.1 15.5 413.7 15.6 145.6 67.1 75.7 183.9 91.8 122.8 17.5 12.9 307.6 376.9 170.9 126.9 132.6 24.7 15.9 117.8 19.8 34.4 6.7 30.1 138.0 187.2 11.7 59.3 11.7 75.5 19.3 90.7 41.2 9.9 22.7 28.8 78.9 48.4 219.0 244.5 77.5 6.9 221.6 214.8 22.3 67.8 95.4 65.7 54.9 118.0 30.8 10.4 100.0 291.5 64.0 33.3 62.4 244.3 385.1 LIMD1 ENSG00000144791 "LIM domains containing 1" Q9UGP4 3 45555394-45686341 "Plasma proteins, Predicted intracellular proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation" Repressor "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 74.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064220, HPA071736" Approved Supported "Nucleoplasm,Focal adhesion sites" NA NA 8100 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Focal adhesion sites" "HPA064220: AB_2685216, HPA071736: " "unprognostic (2.77e-1)" "unprognostic (3.22e-2)" "unprognostic (5.43e-2)" "unprognostic (7.78e-2)" "unprognostic (6.53e-2)" "unprognostic (2.07e-2)" "unprognostic (9.44e-2)" "unprognostic (1.53e-2)" "unprognostic (1.11e-1)" "unprognostic (2.42e-1)" "unprognostic (6.88e-2)" "unprognostic (2.11e-3)" "prognostic favorable (6.73e-5)" "unprognostic (8.02e-2)" "unprognostic (3.06e-2)" "unprognostic (2.86e-2)" "unprognostic (6.61e-3)" 7.1 3.8 4.3 7.8 4.7 6.0 5.4 3.5 4.8 5.4 9.5 7.3 7.1 6.6 4.6 5.6 6.1 7.2 9.7 3.5 3.8 3.7 11.1 17.1 10.6 8.3 5.4 4.1 10.2 9.0 2.8 6.4 6.6 6.2 7.5 2.8 9.8 4.8 17.4 6.5 7.9 5.5 4.7 10.8 8.2 2.5 6.9 8.0 12.2 8.6 8.6 6.0 4.8 6.9 13.3 24.7 8.8 11.9 7.6 14.7 17.7 12.4 17.0 12.7 11.0 11.7 6.8 1.7 8.1 11.4 26.1 8.8 18.8 10.0 10.5 28.1 11.7 14.7 20.5 9.7 7.7 13.3 18.2 6.2 8.3 19.1 10.0 9.2 11.3 14.7 12.4 40.0 12.6 8.7 16.2 8.3 14.2 10.4 23.7 7.9 10.3 20.2 6.8 23.3 4.1 8.0 10.5 18.8 12.4 9.0 11.4 11.8 20.7 14.3 12.9 14.5 13.4 38.1 52.7 6.5 30.9 11.7 16.0 3.8 0.9 1.1 1.0 2.0 0.6 2.4 0.8 0.8 0.9 4.0 0.8 0.8 1.0 0.7 4.0 5.8 0.8 0.8 4.3 4.7 3.5 4.8 3.5 3.8 8.3 5.4 6.6 4.7 6.9 6.9 5.0 38.5 27.4 17.6 17.8 2.9 5.7 4.3 4.0 1.6 5.2 3.8 16.5 21.5 12.4 7.3 2.1 6.4 23.9 8.0 1.9 7.2 1.2 7.9 10.2 5.9 6.7 10.3 1.4 5.3 12.8 9.0 9.7 10.7 3.8 11.1 9.7 22.9 17.1 6.7 3.6 15.9 10.2 17.0 10.1 0.9 11.8 13.5 5.4 18.7 11.1 4.8 12.3 74.4 22.5 6.2 6.9 3.4 9.7 9.1 5.9 2.9 11.9 1.5 6.6 8.2 15.2 1.0 3.5 4.1 2.3 5.3 7.9 2.5 9.6 5.4 LIMS1 "PINCH, PINCH1" ENSG00000169756 "LIM zinc finger domain containing 1" P48059 2 108534355-108687246 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 379.6;Macrophages: 405.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 402.5" "HPA058455, HPA061230" Approved Approved "Focal adhesion sites,Cytosol" NA NA 10000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "Focal adhesion sites" "HPA058455: AB_2683723, HPA061230: AB_2684456" "unprognostic (1.79e-1)" "unprognostic (8.82e-3)" "unprognostic (5.66e-2)" "unprognostic (1.17e-2)" "unprognostic (1.52e-1)" "unprognostic (4.23e-2)" "unprognostic (1.08e-3)" "unprognostic (1.09e-1)" "unprognostic (8.96e-2)" "unprognostic (1.18e-1)" "unprognostic (5.95e-3)" "unprognostic (2.09e-1)" "prognostic unfavorable (7.88e-4)" "unprognostic (7.51e-2)" "unprognostic (8.60e-3)" "unprognostic (1.43e-2)" "unprognostic (2.11e-1)" 41.0 45.0 7.0 33.8 10.4 32.9 28.9 9.4 8.4 22.7 10.8 22.1 16.7 35.8 11.6 26.9 31.5 31.2 38.0 6.9 11.4 16.7 20.1 37.0 37.9 12.9 11.0 20.5 15.0 12.0 8.0 32.2 12.8 19.5 18.0 11.5 17.6 26.7 99.1 14.2 20.0 35.8 11.3 21.0 22.2 16.8 15.0 21.4 24.8 35.8 32.8 30.0 17.6 15.9 44.7 49.0 19.0 22.8 30.8 44.5 91.6 49.0 56.0 37.1 37.6 85.3 93.7 43.1 145.4 63.0 55.0 28.3 29.0 50.2 49.3 106.7 52.0 225.6 32.1 45.8 70.4 42.7 402.5 43.5 45.5 98.3 80.3 44.2 135.9 37.3 81.0 58.2 115.4 36.5 41.4 31.4 37.5 29.0 49.6 52.2 65.9 35.0 70.2 79.5 34.3 46.3 76.6 32.5 34.5 25.0 16.8 39.6 184.2 166.6 75.6 37.5 101.2 56.4 81.6 60.6 139.3 47.6 43.6 211.9 69.6 196.2 16.6 119.3 30.5 18.7 72.3 22.4 59.4 18.0 19.2 7.3 31.6 35.9 156.2 7.7 89.0 140.3 7.0 10.4 9.4 8.4 6.9 11.4 12.9 11.0 12.8 11.3 15.0 15.9 143.5 99.3 55.6 80.6 43.2 74.1 63.0 65.1 63.7 26.2 34.9 37.0 61.6 38.6 53.4 29.5 54.2 45.1 40.6 19.2 39.2 80.9 22.5 266.8 122.9 187.6 118.1 84.5 32.6 233.5 130.3 109.4 32.6 379.6 101.4 107.0 76.1 34.6 189.0 15.2 34.6 24.0 48.8 181.1 265.4 12.0 81.4 405.4 44.4 115.2 118.5 69.2 41.2 54.3 66.8 122.3 17.2 88.0 76.3 82.1 33.5 44.0 84.8 18.8 65.7 116.2 161.2 45.4 51.1 75.2 77.0 27.9 82.4 51.3 32.4 66.4 LIMS2 "PINCH-2, PINCH2" ENSG00000072163 "LIM zinc finger domain containing 2" Q7Z4I7 2 127638381-127681786 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 510.1" "Cell type enhanced" "Detected in many" "Adipocytes: 109.4;Cardiomyocytes: 91.7;Endothelial cells: 105.1;Granulosa cells: 134.1;Hepatic stellate cells: 134.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 22.5" "Group enriched" "Detected in many" 13 "B-cells: 22.5;T-cells: 10.7" "Cell line enhanced" "Detected in many" "BJ hTERT+: 27.0;fHDF/TERT166: 31.2;HHSteC: 32.7;MOLT-4: 40.2;TIME: 83.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058340 Enhanced Supported "Focal adhesion sites" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Focal adhesion sites" "HPA058340: AB_2683683" "unprognostic (2.51e-2)" "unprognostic (1.25e-1)" "unprognostic (5.82e-3)" "unprognostic (4.51e-2)" "unprognostic (9.25e-2)" "unprognostic (3.49e-1)" "prognostic favorable (6.53e-7)" "unprognostic (3.98e-2)" "unprognostic (3.73e-1)" "unprognostic (2.29e-1)" "unprognostic (3.78e-2)" "unprognostic (8.86e-2)" "unprognostic (3.33e-1)" "unprognostic (4.60e-3)" "unprognostic (3.64e-2)" "unprognostic (1.77e-1)" "unprognostic (4.00e-2)" 104.6 21.6 29.4 17.9 27.9 0.4 93.9 24.9 32.3 104.4 25.1 510.1 15.8 261.4 16.9 42.1 139.5 25.7 266.4 25.6 24.1 72.7 46.6 114.3 12.9 28.7 27.2 29.0 14.1 6.4 15.6 27.7 29.3 132.1 15.2 0.6 27.1 98.8 33.4 32.8 95.7 81.9 24.3 121.8 123.1 12.0 32.2 13.1 51.6 26.8 5.4 220.5 85.1 24.0 0.8 1.6 0.5 0.0 4.6 1.0 0.3 19.1 27.0 20.2 18.1 4.7 0.1 0.1 10.3 31.2 1.1 0.1 0.3 0.0 4.2 0.0 0.8 0.0 11.9 3.6 32.7 0.0 0.0 0.2 0.0 7.0 0.2 10.7 12.9 15.3 0.0 0.0 10.0 0.0 40.2 1.0 1.3 0.0 2.4 9.0 1.7 1.0 1.3 0.0 0.1 0.2 3.0 1.7 0.7 6.7 0.7 0.0 83.7 0.1 12.9 15.2 0.1 0.0 0.0 0.2 0.0 1.6 0.0 0.0 0.2 0.0 0.1 0.3 0.0 15.2 5.3 1.1 0.2 22.5 10.7 4.4 0.3 0.0 0.2 1.2 8.0 2.5 29.4 27.9 24.9 32.3 25.6 24.1 28.7 27.2 29.3 24.3 32.2 24.0 109.4 22.4 6.1 0.3 10.1 9.4 0.3 0.2 1.2 0.2 1.9 17.1 91.7 4.3 1.3 0.0 0.0 0.6 0.8 0.1 0.0 1.2 1.3 2.9 5.3 105.1 0.0 5.7 0.4 0.2 12.4 22.5 1.1 0.9 2.5 134.1 134.6 16.3 1.0 0.0 0.3 0.0 0.0 6.5 13.0 3.1 19.9 1.7 10.6 30.9 0.0 0.3 0.0 4.0 0.3 0.5 0.0 49.7 1.7 0.3 0.0 0.5 0.8 0.9 26.3 4.2 35.4 0.8 2.1 0.6 6.7 1.0 2.3 1.8 0.0 0.3 LIMS3 ENSG00000256977 "LIM zinc finger domain containing 3" P0CW19 2 109898428-109924868 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 6.5;fallopian tube: 6.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.6;Distal tubular cells: 1.9;Exocrine glandular cells: 1.2;NK-cells: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "eosinophil: 12.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 14.1;HMC-1: 41.3" HPA058455 Uncertain Approved "Focal adhesion sites,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 11: Alveolar cells - Smell perception" Cytosol "Focal adhesion sites" "HPA058455: AB_2683723" "unprognostic (2.23e-2)" 1.2 1.7 0.2 2.6 0.2 0.4 0.7 0.2 0.4 1.3 0.2 0.5 0.7 6.5 1.7 1.6 6.4 1.3 1.9 0.2 0.3 2.8 0.2 0.5 0.6 0.4 0.3 2.3 0.9 0.5 0.6 1.5 0.4 0.5 1.2 0.4 1.0 1.0 5.7 0.2 0.8 1.5 0.2 0.5 0.7 1.2 0.3 1.0 0.6 2.0 0.4 1.7 0.3 0.5 0.1 0.1 1.8 2.1 0.7 0.6 0.0 2.2 0.0 0.4 0.9 2.2 0.0 0.0 6.5 0.4 4.2 1.2 0.0 2.6 1.8 3.5 0.0 14.1 0.6 1.3 1.9 2.5 41.3 3.0 1.5 1.6 1.9 0.0 3.5 0.0 3.0 2.3 4.6 0.1 0.0 0.3 2.2 1.4 0.8 2.6 4.4 1.5 1.2 2.2 0.6 5.0 5.7 0.0 1.2 0.1 0.0 0.7 10.4 8.8 8.1 4.6 0.4 0.0 0.0 2.8 1.2 0.0 2.6 5.6 3.2 12.3 0.7 5.4 1.4 0.6 4.7 1.5 2.4 0.2 0.8 0.3 0.6 1.2 5.7 0.2 6.1 8.5 0.2 0.2 0.2 0.4 0.2 0.3 0.4 0.3 0.4 0.2 0.3 0.5 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.3 0.1 0.6 0.0 0.0 0.0 1.2 0.0 0.3 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.1 LIMS4 LIMS3L ENSG00000256671 "LIM zinc finger domain containing 4" P0CW20 2 110446640-110473075 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Exocrine glandular cells: 1.5;Glandular and luminal cells: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 1.0;hTEC/SVTERT24-B: 1.8;HUVEC TERT2: 1.0;U-138 MG: 1.9" HPA058455 Uncertain Uncertain "Focal adhesion sites,Cytosol" NA NA "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" Cytosol "Focal adhesion sites" "HPA058455: AB_2683723" "unprognostic (2.12e-1)" 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 1.8 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.6 0.3 0.1 0.0 0.0 0.0 1.5 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 LMLN "Gp63, LMNL1, Msp" ENSG00000185621 "Leishmanolysin like peptidase" Q96KR4 3 197960200-198043720 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 39.7;Endometrial ciliated cells: 35.2;Respiratory ciliated cells: 37.5;Spermatocytes: 33.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016481, HPA028844" Uncertain Supported "Focal adhesion sites,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 16: U-266 - Nucleosome" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "Focal adhesion sites" "HPA016481: AB_1852955, HPA028844: AB_10602347" "unprognostic (2.54e-1)" "unprognostic (3.15e-1)" "unprognostic (7.63e-2)" "prognostic favorable (6.77e-4)" "unprognostic (1.14e-2)" "unprognostic (1.19e-1)" "unprognostic (1.30e-1)" "unprognostic (4.07e-2)" "unprognostic (1.94e-1)" "unprognostic (2.31e-1)" "unprognostic (6.36e-2)" "unprognostic (2.98e-1)" "unprognostic (4.82e-3)" "unprognostic (8.78e-2)" "unprognostic (7.65e-2)" "unprognostic (1.01e-1)" "unprognostic (1.63e-1)" 2.1 2.6 2.7 1.2 3.4 1.2 2.2 3.6 4.7 3.1 4.7 2.1 1.0 2.2 10.7 2.2 4.9 2.6 3.3 2.7 3.7 3.4 2.2 2.5 1.3 4.2 3.3 3.3 3.8 3.8 6.5 2.0 4.5 2.3 2.0 9.7 2.4 3.4 2.4 3.4 1.4 2.0 3.0 1.5 2.0 10.1 4.0 1.1 4.1 2.0 1.2 1.9 2.3 3.2 7.7 2.8 3.3 4.0 6.4 9.0 2.9 3.9 3.6 6.9 5.6 2.8 2.7 2.4 17.7 2.8 14.9 2.8 3.1 3.1 10.0 0.3 2.3 1.4 2.3 2.1 4.0 4.4 2.0 4.3 6.8 8.6 5.5 4.0 3.0 6.0 7.5 4.5 6.7 5.7 2.6 3.8 3.8 5.5 6.7 3.0 0.8 2.6 7.1 2.0 5.4 1.5 5.4 4.8 3.9 3.7 12.5 3.2 6.6 8.4 1.3 10.3 6.7 8.0 16.7 0.7 12.0 7.4 7.8 0.0 0.1 0.1 0.2 0.4 0.3 0.4 0.1 0.3 0.4 0.2 0.4 0.5 0.1 0.3 0.2 0.1 0.0 0.2 2.7 3.4 3.6 4.7 2.7 3.7 4.2 3.3 4.5 3.0 4.0 3.2 4.4 16.0 14.8 24.5 1.7 2.0 1.5 2.6 4.0 8.1 6.4 4.8 11.6 2.8 9.2 9.2 16.7 3.6 1.2 2.2 0.0 3.5 39.7 35.2 11.5 3.2 4.8 0.8 25.3 2.7 2.2 5.5 1.5 11.5 2.5 6.3 4.2 3.1 5.0 8.4 23.1 3.6 0.0 1.9 2.3 21.9 4.7 2.3 3.6 9.4 1.1 5.9 1.0 6.6 13.7 2.1 1.0 5.7 2.1 1.8 0.7 3.5 37.5 17.7 0.0 6.6 3.8 33.2 23.6 3.7 1.7 2.9 2.1 10.6 2.8 1.1 LPP ENSG00000145012 "LIM domain containing preferred translocation partner in lipoma" Q93052 3 188153284-188890671 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 566.5;Late spermatids: 1737.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 18.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 97.0;EFO-21: 115.2;U-698: 200.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA011133, HPA017342" Enhanced Supported "Focal adhesion sites,Cytosol" NA NA 2700000 "Cluster 1: Neutrophils - Mixed function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" "Focal adhesion sites, Cytosol" "HPA011133: AB_1853247, HPA017342: AB_1853249" "unprognostic (1.50e-1)" "unprognostic (4.97e-3)" "unprognostic (1.41e-1)" "unprognostic (2.18e-1)" "unprognostic (1.86e-1)" "unprognostic (4.05e-1)" "unprognostic (2.43e-3)" "unprognostic (7.97e-2)" "unprognostic (2.17e-1)" "unprognostic (5.56e-2)" "unprognostic (3.44e-3)" "unprognostic (2.10e-1)" "unprognostic (2.57e-3)" "unprognostic (2.25e-2)" "unprognostic (6.86e-2)" "unprognostic (2.82e-3)" "unprognostic (1.48e-1)" 29.3 10.8 6.7 28.4 8.9 9.9 18.8 9.1 9.7 27.5 27.3 73.3 13.8 61.9 11.8 49.4 32.2 21.3 16.7 6.1 11.2 11.5 12.1 19.1 17.2 15.6 7.9 14.7 8.8 9.9 2.9 11.5 12.6 39.0 31.7 2.4 12.0 53.1 12.4 12.0 23.0 81.3 6.6 10.8 32.7 18.6 13.8 8.0 8.8 9.1 21.4 57.0 22.1 7.8 25.6 23.3 16.7 11.3 35.3 36.0 17.9 16.0 20.9 11.8 7.8 42.2 12.1 97.0 115.2 37.3 14.7 10.7 5.2 11.0 29.5 10.7 5.7 4.6 18.4 11.1 15.0 2.0 5.5 25.7 15.3 26.4 22.5 16.9 20.1 5.2 0.2 2.0 21.0 8.1 5.1 2.1 6.6 16.3 7.6 6.2 12.3 0.5 13.1 26.8 1.1 0.3 35.3 11.4 19.2 27.3 9.0 8.8 43.7 27.1 20.8 19.6 41.1 0.2 4.0 200.0 13.6 4.3 24.9 0.8 4.9 2.2 5.1 4.5 3.3 3.3 4.5 3.8 2.6 5.6 2.4 2.9 18.9 4.8 4.6 5.3 1.8 1.9 6.7 8.9 9.1 9.7 6.1 11.2 15.6 7.9 12.6 6.6 13.8 7.8 104.7 89.8 69.8 357.5 48.5 78.0 84.9 65.0 70.0 9.5 141.8 111.5 143.0 100.1 86.2 69.9 14.6 44.7 65.7 207.1 29.4 139.7 566.5 49.3 134.4 91.8 77.5 12.0 132.8 90.9 24.1 124.9 97.9 93.6 18.3 136.6 126.4 94.8 42.5 5.0 191.2 91.7 44.7 65.1 121.0 1737.1 225.3 75.8 80.0 308.2 55.8 24.8 54.6 395.6 214.9 120.2 158.1 476.9 24.6 172.5 127.5 80.2 60.9 7.1 335.2 159.2 368.2 9.8 8.0 64.2 68.2 18.6 55.3 46.8 151.3 149.3 LPXN LDPL ENSG00000110031 Leupaxin O60711 11 58526871-58578220 "Predicted intracellular proteins" "Cell adhesion, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 118.5" "Cell type enhanced" "Detected in many" "B-cells: 75.9;dendritic cells: 80.7;Langerhans cells: 154.6;Macrophages: 81.7;Plasma cells: 82.2;T-cells: 90.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 200.7;HMC-1: 329.3;Karpas-707: 285.0;U-2197: 199.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043741, CAB046478, HPA061441" Enhanced Supported "Nuclear speckles,Focal adhesion sites,Cytosol" No No "Cluster 13: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "Focal adhesion sites" "Nuclear speckles, Cytosol" "CAB046478: AB_10603113, HPA043741: AB_2678647, HPA061441: AB_2684518" "unprognostic (1.61e-3)" "unprognostic (6.91e-2)" "unprognostic (6.54e-2)" "prognostic favorable (8.81e-4)" "unprognostic (5.16e-2)" "unprognostic (2.07e-3)" "unprognostic (2.16e-2)" "unprognostic (8.87e-3)" "unprognostic (5.18e-2)" "unprognostic (3.96e-2)" "unprognostic (2.39e-2)" "unprognostic (3.05e-1)" "unprognostic (3.60e-3)" "unprognostic (1.91e-1)" "unprognostic (5.25e-2)" "unprognostic (2.55e-1)" "unprognostic (2.41e-3)" 10.4 8.3 7.5 48.3 8.2 10.2 10.2 7.8 11.8 7.9 4.5 14.5 10.9 7.4 11.9 5.2 7.6 15.1 5.3 7.1 7.8 10.6 14.0 33.5 87.1 9.1 8.8 9.5 8.6 6.5 7.2 5.2 10.2 9.4 19.6 7.0 11.0 7.1 3.8 5.9 26.2 9.7 8.6 44.1 13.0 10.2 10.0 103.3 10.2 5.1 118.5 32.4 6.0 10.9 1.7 2.1 2.0 3.9 7.4 9.3 1.4 50.5 200.7 12.4 22.0 0.4 5.1 149.8 2.0 61.9 9.2 2.0 1.7 137.7 51.4 65.4 0.9 6.8 1.3 1.0 12.8 41.1 329.3 7.2 3.2 170.8 22.0 12.0 80.9 90.0 1.9 285.0 101.5 1.1 144.8 51.6 1.6 2.3 45.8 2.1 2.5 129.2 8.3 71.2 1.0 1.6 2.2 3.2 20.1 2.8 2.7 11.7 79.8 30.8 9.5 199.5 45.9 18.4 18.9 146.5 71.6 36.8 71.6 6.3 74.3 12.2 101.3 41.8 148.9 71.9 102.9 117.6 137.5 46.2 79.6 95.9 14.1 79.2 22.2 124.4 152.1 98.8 7.5 8.2 7.8 11.8 7.1 7.8 9.1 8.8 10.2 8.6 10.0 10.9 4.1 0.0 6.7 22.9 75.9 9.7 6.6 7.2 3.4 4.1 4.0 4.7 2.3 4.3 2.8 0.0 4.2 2.8 80.7 4.2 3.9 2.5 23.0 2.8 1.9 5.9 6.1 13.3 18.2 5.6 1.3 6.6 13.3 2.3 51.5 5.4 2.5 7.6 44.0 1.7 19.8 3.1 6.1 63.7 154.6 8.7 1.8 81.7 19.6 30.0 52.9 2.8 49.4 11.6 27.3 4.1 5.2 3.8 82.2 3.6 6.9 5.7 4.3 4.4 6.6 3.6 3.8 9.2 4.2 2.6 9.7 2.5 90.3 2.9 5.2 27.6 LRCH4 "LRN, LRRN1" ENSG00000077454 "Leucine rich repeats and calponin homology domain containing 4" O75427 7 100574011-100586129 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 205.8;Syncytiotrophoblasts: 103.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 79.6;NB-4: 174.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037667, HPA037668" Enhanced Approved "Nucleoplasm,Focal adhesion sites,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 24: NB-4 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoplasm, Focal adhesion sites, Cytosol" "HPA037667: AB_10671882, HPA037668: AB_10672910" "unprognostic (2.41e-1)" "unprognostic (2.53e-2)" "prognostic unfavorable (1.61e-7)" "unprognostic (8.32e-3)" "unprognostic (2.76e-2)" "unprognostic (3.96e-3)" "unprognostic (8.98e-3)" "unprognostic (3.72e-2)" "unprognostic (2.52e-1)" "unprognostic (5.51e-2)" "unprognostic (2.63e-3)" "unprognostic (7.81e-2)" "unprognostic (1.95e-1)" "unprognostic (1.77e-1)" "unprognostic (1.40e-2)" "unprognostic (7.96e-2)" "unprognostic (1.26e-2)" 29.0 37.5 15.8 25.3 18.3 49.2 26.8 16.8 26.1 32.5 17.0 32.7 19.1 28.3 5.1 35.8 33.7 8.5 28.0 15.5 17.7 35.5 30.9 52.0 33.6 21.4 17.1 55.3 33.5 12.7 51.2 10.9 20.5 36.1 5.5 21.4 36.3 8.8 41.4 30.3 71.6 5.3 16.0 130.1 31.2 112.3 20.3 27.1 47.8 7.2 14.7 24.3 29.9 23.1 15.2 9.8 8.5 9.2 6.5 4.3 17.3 14.5 7.3 9.0 7.1 16.6 24.7 9.9 17.0 3.6 10.7 15.9 5.5 7.0 3.0 10.5 12.2 9.8 12.0 8.1 18.4 18.0 79.6 8.0 7.5 7.6 5.5 7.6 10.3 27.6 18.5 18.7 6.6 32.2 21.2 174.5 11.5 20.5 11.2 25.6 7.1 13.9 10.3 4.2 12.5 18.6 7.8 25.6 20.2 16.2 13.6 40.5 14.4 12.2 23.6 15.2 9.1 23.3 9.9 9.9 9.1 51.6 22.3 22.5 10.6 14.6 5.8 8.4 5.5 6.1 5.9 6.8 7.0 6.6 7.9 6.9 30.6 1.6 5.9 7.7 6.3 3.7 15.8 18.3 16.8 26.1 15.5 17.7 21.4 17.1 20.5 16.0 20.3 23.1 7.5 9.6 12.7 7.5 29.4 12.0 15.4 13.0 5.7 15.9 14.8 8.4 0.8 27.1 15.1 22.0 41.7 39.4 42.9 27.2 15.6 32.7 205.8 11.9 7.7 9.9 6.1 12.2 7.3 24.7 13.9 9.1 14.8 13.5 19.6 12.7 15.4 13.8 32.8 13.5 7.9 11.8 20.3 65.9 33.6 32.3 24.8 40.5 14.2 3.7 66.1 13.6 46.4 4.5 5.2 28.9 13.1 10.1 15.7 12.8 41.9 6.9 12.1 33.5 19.7 9.8 13.3 58.3 33.9 9.0 11.5 103.3 33.7 12.0 10.0 16.4 MDC1 "Em:AB023051.5, KIAA0170, NFBD1" ENSG00000137337 "Mediator of DNA damage checkpoint 1" Q14676 6 30699807-30717447 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Spermatocytes: 74.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "NK-cell: 3.2" "Lineage enriched" "Detected in single" 4 "NK-cells: 3.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006915 Enhanced Supported "Nucleoplasm,Nuclear bodies,Focal adhesion sites" No No "Cluster 48: NK-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Nuclear bodies" "Focal adhesion sites" "HPA006915: AB_1853669" "unprognostic (8.52e-2)" "unprognostic (4.32e-1)" "unprognostic (4.11e-2)" "unprognostic (2.66e-2)" "unprognostic (1.60e-1)" "unprognostic (1.61e-1)" "unprognostic (5.40e-3)" "unprognostic (1.13e-1)" "unprognostic (1.09e-2)" "unprognostic (9.44e-2)" "unprognostic (2.74e-3)" "unprognostic (1.31e-1)" "unprognostic (1.62e-2)" "unprognostic (3.86e-2)" "unprognostic (2.99e-1)" "unprognostic (4.39e-3)" "unprognostic (3.23e-1)" 11.3 7.0 2.7 8.6 3.2 13.0 10.9 4.1 5.2 12.4 3.3 11.0 4.9 13.7 8.5 6.2 12.3 4.6 9.5 2.4 4.1 8.2 9.7 9.5 10.2 4.5 3.3 16.8 10.8 8.6 12.8 7.4 3.5 10.1 6.9 14.1 9.1 8.2 11.0 9.4 10.9 8.9 2.0 11.3 8.4 28.2 3.4 14.5 16.4 5.8 11.3 10.7 9.3 3.6 36.7 11.1 47.4 34.8 6.3 10.0 23.0 14.8 10.0 25.2 21.3 22.7 8.5 37.7 17.5 17.0 23.5 20.2 63.0 28.6 34.9 29.9 65.6 43.4 28.7 12.5 4.1 27.1 16.9 7.9 9.2 48.6 27.3 9.0 11.5 25.7 61.0 36.7 19.1 14.7 14.6 20.0 20.6 8.4 7.8 33.2 24.7 37.4 11.0 10.7 39.9 23.2 11.5 26.2 13.5 29.1 21.8 16.8 13.8 24.8 26.4 19.2 26.3 19.3 21.6 34.5 7.8 63.9 34.3 0.1 0.1 0.1 0.6 0.1 0.3 0.4 0.4 0.5 0.1 0.7 0.5 0.5 0.0 3.2 0.1 0.7 0.0 0.3 2.7 3.2 4.1 5.2 2.4 4.1 4.5 3.3 3.5 2.0 3.4 3.6 9.7 16.0 13.0 10.1 13.4 4.5 5.5 5.6 15.9 11.5 6.8 8.6 7.6 7.2 5.7 5.5 8.4 7.9 11.0 2.5 3.9 5.3 4.7 8.0 8.7 9.7 6.7 14.5 8.3 6.2 11.4 11.2 4.1 13.7 17.1 12.8 6.1 12.0 6.7 5.0 8.1 3.3 12.2 6.0 5.7 3.9 7.8 7.3 1.8 11.2 5.9 10.6 14.4 12.5 9.9 5.2 1.1 6.0 16.9 2.9 1.2 3.0 8.0 17.1 13.1 16.2 8.3 74.5 18.0 8.7 3.7 1.9 12.1 7.7 6.0 1.9 MISP "C19orf21, Caprice, DKFZp686H18209, MISP1" ENSG00000099812 "Mitotic spindle positioning" Q8IVT2 19 751112-764318 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "intestine: 196.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 793.4;Intestinal goblet cells: 230.9;Paneth cells: 646.7;Proximal enterocytes: 1115.2;Undifferentiated cells: 220.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 133.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 121.4;HaCaT: 90.2;hTCEpi: 82.6;MCF7: 63.2;OE19: 76.9;SK-BR-3: 134.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA049511, HPA062232" Enhanced Enhanced "Plasma membrane,Focal adhesion sites" No No "Cluster 9: Intestine - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Focal adhesion sites" "HPA049511: AB_2680798, HPA062232: AB_2684719" "unprognostic (7.48e-2)" "unprognostic (2.04e-1)" "unprognostic (1.44e-1)" "unprognostic (3.99e-2)" "unprognostic (1.02e-1)" "unprognostic (6.50e-2)" "unprognostic (1.78e-3)" "unprognostic (1.64e-2)" "unprognostic (8.64e-2)" "unprognostic (1.49e-1)" "unprognostic (2.56e-3)" "unprognostic (2.09e-1)" "unprognostic (1.19e-3)" "unprognostic (6.78e-3)" "unprognostic (2.29e-1)" "unprognostic (4.80e-1)" "unprognostic (5.27e-2)" 1.3 0.0 0.3 12.1 0.3 0.0 0.9 0.5 0.4 4.4 0.1 95.5 171.0 0.7 0.0 0.3 9.8 11.3 0.0 0.4 0.3 8.8 0.1 9.3 0.1 0.5 0.5 0.3 1.7 0.0 8.1 1.2 0.5 5.6 48.4 0.0 1.0 0.5 0.0 0.6 196.6 3.3 0.2 0.0 22.9 0.5 0.3 0.3 0.1 0.0 0.0 9.0 0.6 0.2 30.4 121.4 0.0 0.1 0.0 0.0 1.4 0.0 0.0 0.1 0.0 42.1 44.2 10.8 11.5 0.0 0.1 90.2 0.0 37.7 0.0 0.0 0.1 0.0 47.0 13.3 0.0 0.0 1.9 0.0 82.6 0.3 4.5 0.0 0.0 0.0 0.0 0.4 0.2 63.2 0.1 0.7 0.1 76.9 24.6 0.2 0.4 1.0 30.1 33.7 1.4 0.4 42.9 134.3 0.1 0.1 29.3 0.0 0.0 0.0 14.8 1.8 0.2 0.6 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.5 0.4 0.4 0.3 0.5 0.5 0.5 0.2 0.3 0.2 0.1 38.5 8.0 0.3 2.9 0.1 4.5 22.5 0.0 0.0 4.7 2.3 0.5 10.0 39.7 11.0 0.0 0.6 0.0 793.4 1.9 39.9 0.6 40.5 1.5 0.8 58.0 0.0 0.2 46.0 6.0 2.4 56.6 14.3 8.9 0.0 0.0 0.0 0.1 0.0 0.3 230.9 28.5 0.0 0.0 0.9 0.0 0.6 0.0 1.0 0.6 0.0 0.0 0.0 0.2 157.7 646.7 0.0 0.1 41.6 1115.2 27.5 41.3 0.0 0.0 0.0 2.6 0.0 1.2 0.0 0.3 2.1 1.6 0.0 220.7 62.1 MMP28 "EPILYSIN, MM28, MMP-25, MMP-28" ENSG00000271447 "Matrix metallopeptidase 28" Q9H239 17 35756249-35795707 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 47.7;Basal respiratory cells: 56.8;Distal enterocytes: 82.0;Paneth cells: 46.2;Proximal enterocytes: 47.2;Urothelial cells: 43.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "naive CD4 T-cell: 6.3;naive CD8 T-cell: 3.7" "Lineage enriched" "Detected in single" 7 "T-cells: 6.3" "Cell line enhanced" "Detected in some" "CAPAN-2: 13.8;HaCaT: 86.9;hTCEpi: 38.3;OE19: 41.7;RT4: 15.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057288, HPA057890" Approved "Nucleoplasm,Focal adhesion sites" "Secreted to extracellular matrix" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Focal adhesion sites" "HPA057288: , HPA057890: " "unprognostic (7.99e-3)" "unprognostic (3.27e-1)" "unprognostic (2.20e-1)" "unprognostic (1.01e-1)" "unprognostic (7.52e-2)" "unprognostic (1.63e-1)" "unprognostic (6.90e-2)" "unprognostic (1.09e-2)" "unprognostic (1.51e-1)" "unprognostic (1.99e-1)" "prognostic unfavorable (6.28e-6)" "unprognostic (9.37e-2)" "unprognostic (1.31e-1)" "unprognostic (8.87e-2)" "unprognostic (1.74e-1)" "unprognostic (1.76e-2)" "unprognostic (3.27e-3)" 14.7 2.0 18.7 0.5 18.1 0.2 8.3 12.1 18.8 4.1 11.9 17.5 1.8 5.2 2.1 13.5 6.1 1.4 3.8 16.2 15.6 1.9 0.3 14.1 0.2 15.2 17.8 1.1 0.8 0.1 1.3 2.0 12.9 5.0 10.5 3.0 2.5 3.5 1.8 23.7 10.2 4.1 14.4 1.1 8.8 22.3 19.3 0.3 5.9 2.4 3.2 16.3 7.6 13.9 0.2 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 13.8 0.1 1.5 0.0 0.1 86.9 0.0 0.2 0.0 0.0 0.7 0.0 0.2 0.0 4.3 0.0 0.0 1.2 38.3 0.0 3.1 0.7 0.3 0.3 0.0 0.2 0.0 0.3 0.1 0.3 0.0 41.7 0.1 0.8 0.0 0.0 0.0 15.7 0.2 0.7 0.8 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.1 0.6 0.2 1.0 0.0 0.4 6.3 3.7 0.0 0.9 0.2 0.9 0.0 0.4 18.7 18.1 12.1 18.8 16.2 15.6 15.2 17.8 12.9 14.4 19.3 13.9 31.5 28.9 26.5 47.7 0.4 38.5 5.3 56.8 21.1 2.7 1.0 1.5 1.3 7.2 15.2 7.3 0.0 0.0 0.2 82.0 0.0 1.2 6.7 0.1 0.0 16.8 3.6 0.4 2.8 0.4 0.0 4.4 12.2 0.1 0.0 0.0 17.9 0.0 0.1 1.7 4.8 32.9 2.0 0.0 1.8 13.4 1.2 0.5 3.6 10.3 0.4 9.4 1.0 1.0 0.6 16.7 46.2 3.0 0.1 8.6 47.2 0.8 4.5 0.5 6.6 0.7 5.5 1.1 3.7 34.9 33.1 0.0 1.0 0.1 21.5 43.9 MTSS2 "ABBA, ABBA-1, LOC92154, MTSS1L" ENSG00000132613 "MTSS I-BAR domain containing 2" Q765P7 16 70661204-70686053 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 372.5" "Cell type enriched" "Detected in some" 5 "Extravillous trophoblasts: 48.0" "Cancer enhanced" "Detected in all" "glioma: 26.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 299.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048531, HPA066469" Approved Supported "Focal adhesion sites" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 20: HeLa - Mitochondria" "Cluster 38: Extravillous trophoblasts - Unknown function" "Focal adhesion sites" "HPA048531: AB_2680430, HPA066469: AB_2685671" "prognostic unfavorable (2.85e-4)" "unprognostic (8.85e-2)" "unprognostic (7.01e-2)" "unprognostic (5.99e-2)" "unprognostic (3.21e-1)" "unprognostic (2.98e-1)" "unprognostic (1.86e-1)" "unprognostic (1.82e-1)" "unprognostic (5.30e-2)" "unprognostic (1.31e-1)" "unprognostic (5.59e-3)" "unprognostic (3.88e-1)" "unprognostic (2.92e-3)" "unprognostic (9.87e-2)" "unprognostic (9.92e-2)" "unprognostic (6.74e-2)" "unprognostic (2.25e-2)" 31.7 40.5 299.2 20.9 295.8 9.4 26.9 283.7 279.1 66.1 102.2 89.2 14.3 78.9 6.1 50.7 47.4 29.0 36.7 296.0 324.9 25.3 106.0 47.2 10.1 372.5 316.2 35.6 13.7 12.8 25.0 36.0 311.5 42.1 8.2 25.6 30.6 37.1 81.1 32.6 27.4 60.0 254.5 58.3 29.9 10.8 313.2 42.5 21.3 29.9 7.9 46.6 46.0 278.5 67.2 157.4 38.9 40.4 31.6 31.2 146.4 98.8 122.0 83.0 68.5 63.8 41.9 0.8 34.6 155.5 33.0 136.9 42.5 43.2 31.5 1.2 56.9 23.2 137.7 299.9 278.1 35.0 1.1 129.3 92.6 38.6 133.0 35.7 27.6 35.0 88.8 1.4 74.8 164.1 33.4 177.8 34.2 22.6 33.1 70.6 72.5 0.4 72.4 99.0 91.1 61.0 210.5 90.6 27.2 36.6 69.9 67.2 41.9 64.3 72.6 59.0 62.7 23.4 6.4 1.2 58.3 1.0 22.5 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.1 299.2 295.8 283.7 279.1 296.0 324.9 372.5 316.2 311.5 254.5 313.2 278.5 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 4.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 48.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 MYH1 "MGC133384, MYHa, MyHC-2X/D, MYHSA1" ENSG00000109061 "Myosin heavy chain 1" P12882 17 10492307-10518542 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Muscle protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 137 "skeletal muscle: 7882.0" "Cell type enriched" "Detected in some" 10 "Skeletal myocytes: 77.4" "Cancer enriched" "Detected in single" 45 "head and neck cancer: 8.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001349, CAB010759" Enhanced Uncertain "Focal adhesion sites" NA NA 98000000 "Cluster 33: Striated muscle - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" "Focal adhesion sites" "CAB010759: AB_477248, HPA001349: AB_1079437" "unprognostic (2.87e-2)" "unprognostic (3.27e-3)" "unprognostic (1.91e-1)" "unprognostic (8.95e-3)" "unprognostic (4.49e-2)" "unprognostic (7.31e-2)" "unprognostic (5.63e-3)" "unprognostic (9.85e-4)" "unprognostic (1.92e-1)" "unprognostic (4.58e-2)" 2.6 0.1 0.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 3.5 0.1 0.1 0.6 0.3 0.0 0.1 0.3 0.4 0.0 0.0 0.0 0.2 0.4 0.0 0.1 0.0 0.0 1.3 0.0 0.0 9.1 0.1 7882.0 0.7 0.2 0.1 0.0 0.1 0.2 1.8 0.0 0.0 0.5 57.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.5 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.6 0.0 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 77.4 0.6 0.1 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 MYH2 "IBM3, MYH2A, MYHas8, MyHC-2A, MyHC-IIa, MYHSA2" ENSG00000125414 "Myosin heavy chain 2" Q9UKX2 17 10521148-10549700 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Muscle protein, Myosin" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 84 "skeletal muscle: 12790.2;tongue: 6140.2" "Cell type enriched" "Detected in some" 18 "Skeletal myocytes: 129.6" "Cancer enriched" "Detected in single" 60 "head and neck cancer: 27.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 4.0;HSkMC: 1.9;NTERA-2: 8.3;SuSa: 1.7" "HPA001349, CAB010760" Enhanced Uncertain "Focal adhesion sites" NA NA 81000000 "Cluster 33: Striated muscle - Muscle contraction" "Cluster 5: NTERA-2 - Transcription" "Cluster 37: Myocytes - Muscle contraction" "Focal adhesion sites" "CAB010760: AB_477190, HPA001349: AB_1079437" "unprognostic (6.50e-2)" "unprognostic (1.86e-2)" "unprognostic (4.76e-2)" "unprognostic (1.92e-2)" "unprognostic (1.05e-4)" "unprognostic (2.89e-1)" "unprognostic (9.51e-2)" "unprognostic (2.03e-2)" "unprognostic (1.09e-2)" "unprognostic (4.30e-2)" 0.5 0.1 0.5 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 1.9 0.0 0.2 0.0 46.5 0.3 0.0 0.5 0.4 0.0 0.2 0.2 0.4 0.0 0.0 0.0 0.3 0.3 0.0 0.1 0.0 0.0 21.5 0.0 0.0 113.1 1.0 12790.2 1.1 0.2 0.4 0.0 0.1 0.2 0.2 0.0 0.3 0.9 6140.2 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 129.6 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 MYH4 "MYH2B, MyHC-2B, MyHC-IIb" ENSG00000264424 "Myosin heavy chain 4" Q9Y623 17 10443290-10469559 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Muscle protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 23 "skeletal muscle: 10.6" "Cell type enriched" "Detected in single" 5 "Cardiomyocytes: 3.3" "Cancer enriched" "Detected in single" 115 "liver cancer: 9.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 25 "OE19: 9.0" HPA001349 Supported Uncertain "Focal adhesion sites" NA NA 86000000 "Cluster 33: Striated muscle - Muscle contraction" "Cluster 21: OE19 - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" "Focal adhesion sites" "HPA001349: AB_1079437" "unprognostic (3.27e-2)" "unprognostic (2.94e-2)" "unprognostic (4.94e-2)" "unprognostic (1.69e-2)" "unprognostic (4.72e-1)" "unprognostic (1.37e-1)" "unprognostic (3.32e-2)" "unprognostic (1.21e-3)" "unprognostic (3.52e-4)" "unprognostic (9.97e-2)" 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 MYH6 ENSG00000197616 "Myosin heavy chain 6" P13533 14 23381982-23408273 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Muscle protein, Myosin" "Atrial septal defect, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 54 "heart muscle: 2882.7" "Cell type enriched" "Detected in some" 17 "Cardiomyocytes: 8051.1" "Cancer enriched" "Detected in single" 5 "testis cancer: 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 23 "NTERA-2: 4.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA001239, HPA001349, CAB075723, CAB075724, CAB075725" Enhanced Uncertain "Focal adhesion sites" NA NA 25000000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 5: NTERA-2 - Transcription" "Cluster 54: Cardiomyocytes - Muscle contraction" "Focal adhesion sites" "CAB075723: AB_2665728, CAB075724: AB_2665729, CAB075725: AB_2665730, HPA001239: AB_1079438, HPA001349: AB_1079437" "unprognostic (2.09e-2)" "unprognostic (8.53e-4)" "unprognostic (1.80e-2)" "unprognostic (2.99e-1)" "unprognostic (1.66e-1)" "unprognostic (2.09e-1)" "unprognostic (1.66e-1)" "unprognostic (5.73e-2)" "unprognostic (1.44e-2)" "unprognostic (5.34e-3)" "unprognostic (6.90e-2)" "unprognostic (1.42e-1)" "unprognostic (1.85e-1)" "unprognostic (1.22e-2)" 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 2882.7 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.9 5.8 0.0 0.0 0.5 0.1 0.9 0.0 0.0 1.9 0.0 53.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 50.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8051.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 31.7 0.0 2.7 0.1 0.0 0.0 449.6 0.0 0.0 0.0 0.3 1.1 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.8 60.3 0.1 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 MYH7 "CMD1S, CMH1, MPD1" ENSG00000092054 "Myosin heavy chain 7" P12883 14 23412740-23435660 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Muscle protein, Myosin" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 71 "heart muscle: 7569.2;skeletal muscle: 14554.3;tongue: 5378.8" "Cell type enriched" "Detected in some" 127 "Cardiomyocytes: 10295.8" "Group enriched" "Detected in some" 9 "head and neck cancer: 12.2;prostate cancer: 15.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 31 "HSkMC: 11.4" "Low region specificity" "Detected in many" "HPA001239, HPA001349, CAB015384" Enhanced Uncertain "Focal adhesion sites" NA NA 43000000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Focal adhesion sites" "CAB015384: AB_2147279, HPA001239: AB_1079438, HPA001349: AB_1079437" "unprognostic (6.49e-2)" "unprognostic (8.27e-5)" "unprognostic (1.56e-1)" "unprognostic (3.04e-3)" "unprognostic (4.30e-1)" "unprognostic (7.33e-3)" "unprognostic (8.60e-2)" "unprognostic (1.55e-1)" "unprognostic (1.31e-1)" "unprognostic (1.22e-1)" "unprognostic (3.79e-1)" "unprognostic (5.38e-3)" "unprognostic (2.32e-1)" "unprognostic (1.20e-1)" "unprognostic (1.41e-1)" "unprognostic (2.28e-2)" 2.0 1.3 1.4 0.0 1.9 0.1 2.5 0.1 1.1 0.3 1.4 1.2 0.5 0.4 0.0 129.2 0.1 1.1 7569.2 1.2 2.9 0.9 1.4 3.2 1.5 0.8 1.6 0.7 7.8 0.0 1.5 0.0 0.9 76.8 0.0 0.0 37.0 0.0 14554.3 4.8 0.9 0.0 0.9 0.5 0.9 1.4 3.2 0.1 1.8 5378.8 0.1 0.2 1.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.9 0.1 1.1 1.2 2.9 0.8 1.6 0.9 0.9 3.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10295.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.2 0.0 80.9 0.0 0.0 0.2 3.1 0.0 70.5 0.0 0.0 0.0 0.0 2.5 0.1 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.7 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 3.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 52.2 51.2 0.1 2.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 MYH8 "MyHC-peri, MyHC-pn" ENSG00000133020 "Myosin heavy chain 8" P13535 17 10390322-10421950 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Muscle protein, Myosin" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "esophagus: 15.9;lymphoid tissue: 10.7;skeletal muscle: 16.7;tongue: 10.0" "Group enriched" "Detected in some" 8 "Proximal tubular cells: 84.8;Skeletal myocytes: 52.0" "Cancer enhanced" "Detected in some" "head and neck cancer: 0.7;renal cancer: 0.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 14 "HSkMC: 7.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001349, CAB016527" Enhanced Uncertain "Focal adhesion sites" NA NA 53000000 "Cluster 59: Non-specific - Translation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 37: Myocytes - Muscle contraction" "Focal adhesion sites" "CAB016527: AB_2147291, HPA001349: AB_1079437" "unprognostic (5.87e-2)" "unprognostic (5.13e-3)" "unprognostic (4.12e-2)" "unprognostic (1.25e-2)" "unprognostic (2.29e-3)" "unprognostic (1.08e-1)" "unprognostic (5.02e-3)" "unprognostic (7.87e-2)" "unprognostic (1.61e-1)" "unprognostic (3.56e-1)" 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.2 0.0 16.7 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 10.7 0.0 10.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 3.7 0.0 0.0 0.0 0.0 7.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 84.8 0.0 0.0 0.0 52.0 0.1 0.5 0.9 0.0 0.0 0.0 0.4 0.0 0.0 0.0 MYO5A "GS1, MYH12, MYO5, MYR12" ENSG00000197535 "Myosin VA" Q9Y4I1 15 52307283-52529050 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.1;parathyroid gland: 47.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 353.0;Inhibitory neurons: 241.0;Oligodendrocyte precursor cells: 330.8;Oligodendrocytes: 404.2" "Cancer enhanced" "Detected in all" "melanoma: 25.2" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 201.0;RPMI-8226: 140.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001356 Enhanced Approved "Focal adhesion sites,Centriolar satellite" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Focal adhesion sites, Centriolar satellite" "HPA001356: AB_1079441" "unprognostic (1.54e-1)" "unprognostic (1.78e-1)" "unprognostic (6.95e-2)" "unprognostic (2.29e-2)" "unprognostic (1.97e-2)" "unprognostic (3.91e-2)" "unprognostic (2.30e-2)" "unprognostic (6.65e-2)" "unprognostic (7.89e-2)" "unprognostic (4.74e-2)" "unprognostic (9.36e-3)" "unprognostic (1.71e-1)" "unprognostic (5.63e-3)" "unprognostic (3.79e-3)" "unprognostic (1.24e-1)" "unprognostic (7.16e-2)" "prognostic unfavorable (4.22e-4)" 10.3 8.3 17.0 12.1 20.8 21.8 6.5 3.0 39.1 6.8 0.0 6.1 3.8 5.0 3.7 5.3 4.0 8.5 5.8 19.0 3.6 5.3 2.9 8.8 15.0 9.6 4.2 5.7 5.2 47.4 8.9 6.3 9.8 5.1 5.9 26.1 5.2 3.5 5.4 11.8 5.0 9.4 0.0 9.5 4.7 5.9 6.6 11.0 8.4 5.0 13.1 9.7 5.3 20.8 19.5 33.7 17.6 21.3 16.2 19.3 19.0 34.7 31.1 18.1 14.0 3.2 7.8 18.7 8.9 41.8 26.5 15.7 40.7 35.6 22.3 105.5 9.6 16.7 8.8 4.2 8.3 9.0 16.3 13.0 21.9 26.6 52.4 17.6 106.8 12.0 0.7 201.0 34.8 34.4 8.2 1.2 8.1 0.5 26.6 14.5 27.8 140.8 15.1 14.0 12.7 7.8 32.3 26.2 59.4 13.1 14.0 9.1 52.0 36.4 15.7 17.1 34.1 20.9 49.9 22.0 39.4 25.1 53.5 0.4 2.4 3.1 1.4 1.7 2.1 1.1 1.3 0.9 2.7 0.7 0.2 0.4 3.0 0.3 1.4 1.5 2.2 1.1 17.0 20.8 3.0 39.1 19.0 3.6 9.6 4.2 9.8 0.0 6.6 20.8 11.2 12.8 11.4 68.2 19.8 20.8 9.3 10.5 7.4 75.1 6.7 5.5 12.1 2.8 19.8 14.7 39.6 0.6 18.4 0.3 0.0 5.4 18.0 9.3 8.0 12.7 1.2 2.5 353.0 6.3 0.4 7.5 3.1 6.7 22.8 5.0 2.5 1.3 24.4 26.9 241.0 0.2 2.0 27.1 28.0 10.8 3.7 50.2 97.8 52.5 36.7 6.0 15.5 330.8 404.2 6.1 2.5 1.9 32.4 10.2 0.0 2.8 11.1 28.7 6.6 16.7 10.8 14.0 9.4 3.9 11.6 1.1 23.7 2.1 0.3 7.3 NOB1 "ART-4, MST158, NOB1P, PSMD8BP1" ENSG00000141101 "NIN1 (RPN12) binding protein 1 homolog" Q9ULX3 16 69741871-69754926 "Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041522, HPA049430, HPA067411" Approved Approved "Focal adhesion sites,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 50: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 32: Non-specific - Translation" Cytosol "Focal adhesion sites" "HPA041522: , HPA049430: AB_2680764, HPA067411: " "unprognostic (5.11e-2)" "unprognostic (4.49e-2)" "unprognostic (3.15e-1)" "unprognostic (8.61e-3)" "unprognostic (9.45e-2)" "prognostic unfavorable (4.21e-5)" "prognostic unfavorable (8.16e-4)" "unprognostic (3.26e-2)" "unprognostic (3.04e-1)" "unprognostic (7.51e-2)" "unprognostic (1.04e-2)" "unprognostic (1.55e-1)" "unprognostic (1.01e-1)" "unprognostic (1.16e-2)" "unprognostic (1.23e-2)" "unprognostic (1.57e-1)" "unprognostic (1.16e-1)" 33.3 51.8 13.5 23.2 18.6 31.1 32.2 14.7 17.3 29.2 18.1 25.1 31.5 28.4 14.0 41.8 43.4 24.3 18.5 13.9 13.4 23.7 24.5 20.6 37.0 15.2 13.9 54.5 90.1 17.7 15.3 20.5 15.2 24.9 19.1 7.0 31.1 19.2 36.6 42.5 23.2 20.1 13.9 27.3 37.1 12.8 15.3 26.5 30.8 20.2 30.1 31.5 31.7 14.9 58.7 125.9 29.0 82.7 63.2 98.6 57.5 46.1 63.6 84.0 75.9 143.5 93.5 129.9 69.9 51.2 44.2 84.9 80.3 102.6 49.4 33.0 93.6 50.8 57.5 186.6 111.3 95.0 40.9 125.5 85.8 96.9 122.6 78.0 71.7 77.0 117.2 39.2 42.5 152.8 119.6 187.9 89.2 64.9 73.8 130.5 30.1 164.6 62.5 56.5 75.0 37.1 144.8 50.1 73.8 25.5 54.4 84.0 55.3 56.8 51.8 52.6 76.0 63.9 52.7 230.1 57.0 85.3 64.2 0.3 37.9 5.7 41.5 32.5 58.1 47.0 50.3 38.5 51.3 53.9 53.3 49.0 1.9 65.7 26.5 26.8 68.2 46.7 13.5 18.6 14.7 17.3 13.9 13.4 15.2 13.9 15.2 13.9 15.3 14.9 31.3 3.2 18.8 4.6 36.2 60.0 75.1 84.7 87.6 10.2 52.3 69.7 5.7 24.3 47.2 20.2 0.0 71.9 22.5 14.2 41.1 47.9 10.7 22.0 42.5 39.9 10.2 37.6 6.9 85.9 82.6 35.8 23.4 26.5 16.5 68.5 32.5 14.8 36.2 5.0 6.7 36.9 36.7 30.7 24.1 7.1 36.7 19.6 21.4 2.8 35.7 11.6 35.0 6.0 5.7 46.9 25.1 42.5 24.8 72.0 35.3 37.4 17.1 5.4 26.3 47.2 30.5 18.1 33.4 64.0 59.7 47.5 30.7 77.4 63.2 67.8 PALMD "C1orf11, FLJ20271, PALML" ENSG00000099260 Palmdelphin Q9NP74 1 99646113-99694541 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 130.8" "Cell type enhanced" "Detected in many" "Adipocytes: 537.2;Cardiomyocytes: 157.6;Endothelial cells: 219.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 155.2;LHCN-M2: 49.5;TIME: 220.5;U-87 MG: 92.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017959, HPA030549" Supported Supported "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Actin filaments" "Plasma membrane, Focal adhesion sites" "HPA017959: AB_1854949, HPA030549: AB_2673518" "unprognostic (1.48e-2)" "unprognostic (1.15e-2)" "unprognostic (2.05e-2)" "prognostic favorable (9.42e-4)" "unprognostic (7.67e-2)" "prognostic favorable (5.90e-5)" "unprognostic (1.54e-2)" "unprognostic (2.10e-1)" "unprognostic (3.93e-2)" "unprognostic (1.64e-1)" "unprognostic (8.32e-2)" "unprognostic (6.18e-2)" "unprognostic (5.19e-2)" "unprognostic (1.63e-2)" "unprognostic (1.88e-1)" "unprognostic (2.70e-1)" "unprognostic (8.08e-2)" 130.8 43.0 14.6 7.1 11.7 0.0 77.6 10.5 15.3 27.4 45.8 9.5 3.4 33.0 6.1 38.2 22.8 14.6 91.2 13.7 12.7 11.0 57.1 28.4 3.9 12.0 11.8 18.8 4.9 9.2 10.5 43.2 11.5 18.0 6.5 7.5 71.0 7.9 112.6 48.9 8.6 31.4 11.1 6.3 6.1 11.0 14.1 8.0 7.2 66.2 8.6 14.5 15.9 10.4 0.0 0.3 0.4 0.2 7.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 39.2 2.5 0.6 10.8 0.0 0.5 0.1 0.1 0.1 0.0 18.6 26.4 0.0 0.0 0.1 3.9 2.0 0.0 0.0 4.3 155.2 0.0 22.7 0.0 49.5 0.6 0.0 0.0 0.0 1.6 6.8 0.0 38.2 0.1 0.0 8.0 0.9 0.5 0.0 9.9 0.0 1.0 2.3 0.0 220.5 0.0 0.4 16.8 0.0 0.0 0.0 0.1 92.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 11.7 10.5 15.3 13.7 12.7 12.0 11.8 11.5 11.1 14.1 10.4 537.2 6.4 5.6 0.3 0.5 38.5 11.4 49.6 22.2 2.0 20.0 31.8 157.6 32.9 35.9 3.7 0.0 0.4 1.6 0.1 5.9 8.1 74.9 78.7 71.9 219.4 1.8 2.7 1.4 0.2 0.3 19.2 2.0 17.7 1.3 0.0 96.0 57.3 0.6 3.3 1.8 0.0 14.2 2.2 5.5 12.2 9.3 1.7 24.9 73.1 0.0 55.0 0.0 0.5 0.2 4.1 0.0 24.0 0.0 5.9 0.0 0.4 111.5 3.3 0.0 91.3 12.7 0.5 0.6 27.5 46.5 0.3 1.4 110.1 0.1 3.3 PARVA "FLJ10793, FLJ12254, MXRA2" ENSG00000197702 "Parvin alpha" Q9NVD7 11 12377563-12535356 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion, Cell shape, Chemotaxis, Cilium biogenesis/degradation" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.0" "Lineage enriched" "Detected in single" 11 "T-cells: 1.0" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 229.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005964 Approved Supported "Actin filaments,Focal adhesion sites,Cytosol" NA NA 7300000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Actin filaments, Focal adhesion sites" Cytosol "HPA005964: AB_1079569" "unprognostic (3.87e-2)" "unprognostic (7.38e-2)" "unprognostic (3.30e-2)" "prognostic favorable (1.76e-4)" "unprognostic (7.37e-3)" "unprognostic (1.38e-2)" "unprognostic (6.78e-2)" "prognostic unfavorable (8.19e-4)" "unprognostic (1.76e-2)" "unprognostic (2.80e-2)" "unprognostic (1.70e-2)" "unprognostic (9.82e-2)" "unprognostic (6.73e-2)" "unprognostic (6.58e-3)" "unprognostic (1.35e-1)" "unprognostic (1.50e-1)" "unprognostic (3.82e-2)" 61.8 17.6 9.3 22.7 9.0 0.1 40.9 7.2 10.1 53.9 16.5 92.4 17.5 71.8 16.7 42.8 38.8 31.9 34.3 9.8 11.6 23.0 16.9 28.8 6.4 11.0 7.3 31.9 36.0 16.9 11.7 35.9 8.4 50.6 38.4 8.9 20.9 68.9 8.1 14.0 26.1 95.5 11.3 11.3 42.5 6.8 8.6 4.6 17.9 11.7 9.1 55.0 28.2 11.0 34.0 33.1 30.2 39.4 147.8 110.6 69.1 126.5 130.1 87.7 81.6 24.7 51.8 0.0 41.1 229.5 9.9 20.7 0.4 66.4 104.0 0.6 14.9 0.1 42.4 18.7 114.7 0.1 0.9 91.3 22.3 37.1 57.4 107.5 110.9 0.0 0.1 0.3 131.8 20.4 0.0 0.2 14.2 20.2 26.4 0.0 75.2 0.2 44.9 32.8 4.8 0.1 97.6 39.1 65.5 66.9 18.4 0.9 138.2 105.1 43.8 57.2 35.4 0.1 0.1 0.2 58.5 0.1 118.3 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 9.0 7.2 10.1 9.8 11.6 11.0 7.3 8.4 11.3 8.6 11.0 37.0 99.3 33.0 47.3 1.1 13.8 25.0 29.3 20.5 4.3 24.4 24.8 45.1 18.6 27.0 27.6 0.0 39.9 0.7 39.6 39.2 56.1 0.9 26.9 62.5 33.3 27.1 0.0 31.4 67.1 92.2 59.1 24.5 35.9 5.1 34.8 39.7 19.1 6.5 0.0 34.9 26.2 18.3 1.8 8.8 2.5 41.0 2.0 46.2 36.5 1.0 25.3 0.0 30.7 1.0 51.7 25.4 51.9 0.2 33.5 23.1 38.1 54.8 2.5 52.6 32.6 60.6 1.1 3.4 20.2 8.9 19.0 2.3 25.1 32.4 25.1 PCDHGA2 PCDH-GAMMA-A2 ENSG00000081853 "Protocadherin gamma subfamily A, 2" Q9Y5H1 5 141338760-141512975 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 1.2;Bipolar cells: 3.2;Cardiomyocytes: 1.8;Fibroblasts: 1.5;Leydig cells: 1.2;Peritubular cells: 2.6;Skeletal myocytes: 1.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 6.4;BJ: 3.9;fHDF/TERT166: 4.4;HSkMC: 3.4;hTERT-RPE1: 3.9" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA038625" Approved Approved "Nucleoplasm,Nucleoli,Vesicles,Plasma membrane,Focal adhesion sites,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Nucleoli, Focal adhesion sites, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA038625: AB_2732480" "unprognostic (2.43e-3)" "unprognostic (2.10e-2)" "unprognostic (1.32e-2)" "unprognostic (4.54e-1)" "unprognostic (2.92e-1)" "unprognostic (1.14e-1)" "unprognostic (3.01e-1)" "unprognostic (2.82e-1)" "unprognostic (1.56e-1)" "unprognostic (1.18e-1)" "unprognostic (9.01e-2)" "unprognostic (4.32e-2)" "unprognostic (8.45e-3)" "unprognostic (9.68e-3)" "unprognostic (1.04e-2)" "unprognostic (1.18e-2)" "unprognostic (2.23e-4)" 2.2 1.6 1.8 0.7 1.4 0.0 1.9 2.7 2.5 3.0 0.7 1.5 0.1 2.9 1.9 0.8 3.1 1.4 4.9 2.9 1.5 1.1 0.7 2.0 0.2 3.8 3.2 6.3 1.8 3.8 2.6 0.7 2.6 1.9 0.3 2.3 1.2 2.2 1.0 1.0 0.6 2.1 3.5 0.6 0.9 2.3 2.6 0.8 1.6 1.1 0.2 1.4 1.7 2.2 0.0 0.7 0.3 0.2 2.8 6.4 0.0 3.9 1.3 0.3 0.5 0.0 0.0 0.1 0.4 4.4 0.5 0.1 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 3.4 0.1 0.0 0.2 3.9 1.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.1 0.5 0.0 0.2 0.5 0.0 2.3 0.1 0.3 0.4 0.0 2.3 0.6 0.3 0.2 0.0 0.0 0.3 0.0 1.5 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.4 2.7 2.5 2.9 1.5 3.8 3.2 2.6 3.5 2.6 2.2 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 3.2 0.3 0.9 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 1.1 0.9 0.0 0.0 0.0 0.2 0.0 1.5 0.0 0.1 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 2.6 0.0 0.0 0.0 0.4 0.0 0.4 0.0 1.5 0.5 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 PCDHGB1 PCDH-GAMMA-B1 ENSG00000254221 "Protocadherin gamma subfamily B, 1" Q9Y5G3 5 141350102-141512979 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.5" "Cell type enhanced" "Detected in some" "Early spermatids: 5.7;Late spermatids: 7.6;Melanocytes: 1.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 12.9;ASC TERT1: 6.6;hTERT-RPE1: 7.1;T-47d: 8.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA076182" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Focal adhesion sites,Midbody" Yes No "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 34: Spermatids - Unknown function" "Vesicles, Plasma membrane" "Nucleoplasm, Focal adhesion sites, Midbody" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA076182: AB_2686783" "unprognostic (1.53e-2)" "unprognostic (1.94e-3)" "unprognostic (3.21e-1)" "unprognostic (4.38e-3)" "unprognostic (2.98e-1)" "unprognostic (8.36e-3)" "unprognostic (2.37e-1)" "unprognostic (9.57e-2)" "unprognostic (8.57e-2)" "unprognostic (1.06e-1)" "unprognostic (3.44e-2)" "unprognostic (4.78e-2)" "unprognostic (6.33e-2)" "unprognostic (3.15e-2)" "unprognostic (8.75e-2)" "unprognostic (1.93e-1)" "unprognostic (7.63e-3)" 0.6 0.7 1.8 0.1 1.2 0.0 0.5 2.1 1.6 0.6 0.0 0.3 0.0 1.2 0.4 0.3 0.4 0.5 0.5 2.9 1.6 0.4 0.1 0.6 0.0 1.9 3.3 1.4 0.8 2.3 1.0 0.2 2.4 0.6 0.1 1.6 0.3 0.9 0.2 0.2 0.1 0.9 2.4 0.1 0.1 0.4 1.8 0.0 0.6 0.3 0.0 0.3 0.3 3.5 0.1 1.9 1.6 0.0 12.9 6.6 0.1 1.2 3.2 0.5 0.7 0.2 0.5 0.5 4.2 0.5 3.1 0.6 0.3 0.2 0.4 0.0 0.8 0.0 0.2 1.2 0.2 0.0 0.0 1.0 0.0 0.0 0.0 7.1 0.1 0.0 0.2 0.2 3.0 1.7 0.4 0.3 0.2 0.0 0.0 0.0 2.4 0.1 0.0 0.0 1.0 0.7 0.0 0.8 0.1 1.2 8.6 0.0 1.0 0.2 1.3 1.1 0.0 0.0 2.4 0.3 2.5 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.2 2.1 1.6 2.9 1.6 1.9 3.3 2.4 2.4 1.8 3.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.7 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 1.8 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 PDLIM2 ENSG00000120913 "PDZ and LIM domain 2" Q96JY6 8 22578279-22598025 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 793.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in all" "white matter: 429.2" "Low region specificity" "Detected in many" HPA003880 Approved Supported "Actin filaments,Focal adhesion sites" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Actin filaments, Focal adhesion sites" "HPA003880: AB_1855149" "unprognostic (1.04e-1)" "unprognostic (3.53e-2)" "unprognostic (1.80e-2)" "unprognostic (1.03e-1)" "unprognostic (1.45e-3)" "unprognostic (9.33e-2)" "unprognostic (3.69e-2)" "unprognostic (4.55e-2)" "unprognostic (1.79e-2)" "unprognostic (1.22e-3)" "unprognostic (1.52e-1)" "unprognostic (3.37e-1)" "prognostic unfavorable (1.37e-7)" "unprognostic (6.14e-2)" "unprognostic (8.17e-2)" "unprognostic (3.47e-2)" "unprognostic (3.08e-3)" 66.0 31.6 40.6 31.9 42.2 23.7 51.0 51.0 56.6 85.1 42.6 86.9 60.9 80.2 9.8 131.4 56.0 52.8 51.4 36.9 43.9 77.7 59.4 88.8 54.4 56.6 52.9 49.6 53.7 9.8 35.3 40.5 59.4 45.5 11.2 2.0 48.6 30.9 201.9 153.1 64.3 23.2 49.9 232.0 38.8 12.2 49.9 20.4 27.4 60.9 24.4 57.5 91.7 54.8 90.3 54.5 36.2 63.9 69.9 118.5 40.9 139.1 102.4 97.6 98.5 62.4 14.7 36.9 38.4 126.4 18.1 44.7 20.5 95.0 19.0 0.1 14.1 11.6 35.2 46.1 88.2 13.0 85.9 127.2 11.6 48.2 13.2 76.8 54.2 20.2 3.3 23.4 67.4 46.5 16.7 15.4 29.8 37.8 5.5 13.3 6.9 3.9 17.3 18.3 11.3 26.9 29.1 78.1 128.7 21.3 27.5 25.8 68.2 105.7 108.6 127.9 64.8 0.4 0.8 12.5 109.0 51.3 79.6 78.2 48.0 162.3 47.0 64.4 42.2 25.0 35.5 46.9 38.4 27.6 23.8 35.4 101.6 28.1 63.8 24.7 40.7 34.6 40.6 42.2 51.0 56.6 36.9 43.9 56.6 52.9 59.4 49.9 49.9 54.8 85.8 76.9 13.1 5.5 45.0 95.1 12.9 48.1 39.9 3.0 34.0 42.5 10.2 18.6 34.2 18.4 0.0 73.1 70.9 92.0 15.6 24.9 1.0 8.8 94.0 48.7 1.2 10.5 3.2 26.1 115.1 98.9 7.7 13.8 27.3 25.7 86.4 49.4 59.0 3.3 2.3 12.6 20.3 59.1 73.8 3.4 132.0 37.9 48.0 8.4 42.5 33.1 122.6 7.1 3.9 93.2 126.1 218.2 6.8 52.7 217.6 146.3 5.2 3.6 59.2 27.1 108.3 0.7 6.3 39.7 100.7 793.0 71.6 21.0 15.0 30.6 PDLIM5 "Enh, LIM" ENSG00000163110 "PDZ and LIM domain 5" Q96HC4 4 94451857-94668227 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "heart muscle: 629.5;skeletal muscle: 1163.5;tongue: 576.0" "Cell type enriched" "Detected in all" 4 "Cardiomyocytes: 1844.2" "Cancer enriched" "Detected in all" 8 "prostate cancer: 132.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "basophil: 219.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 219.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013511, HPA016740, HPA020026" Enhanced Approved "Nucleoplasm,Plasma membrane,Focal adhesion sites" NA NA 1200000 "Cluster 38: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" "Nucleoplasm, Focal adhesion sites" "CAB013511: AB_2533388, HPA016740: AB_1855153, HPA020026: AB_1855154" "unprognostic (6.20e-2)" "unprognostic (1.94e-1)" "unprognostic (2.81e-2)" "unprognostic (1.08e-2)" "unprognostic (6.61e-2)" "unprognostic (2.24e-1)" "unprognostic (1.33e-1)" "unprognostic (2.46e-2)" "unprognostic (7.60e-2)" "unprognostic (2.65e-1)" "unprognostic (1.18e-2)" "unprognostic (1.47e-1)" "unprognostic (1.24e-1)" "unprognostic (2.11e-2)" "unprognostic (3.15e-2)" "unprognostic (1.91e-1)" "unprognostic (1.04e-1)" 41.7 26.0 20.5 25.6 25.2 59.7 39.5 22.4 22.4 27.4 84.9 34.1 33.3 94.8 11.3 72.3 40.5 47.5 629.5 21.4 27.7 34.9 82.7 22.0 16.2 30.9 30.1 27.2 30.2 12.2 17.5 67.7 25.0 88.5 30.8 18.2 40.2 68.9 1163.5 21.5 34.4 105.9 22.7 24.1 31.0 12.7 26.3 10.9 25.5 576.0 21.1 45.8 27.6 21.0 31.4 87.2 33.6 13.0 71.7 51.3 13.0 71.6 59.9 40.1 32.6 80.8 66.3 12.0 72.0 72.3 21.0 31.8 46.5 68.2 65.9 24.1 19.3 43.7 53.8 32.2 103.7 14.6 38.3 66.4 58.4 96.1 74.0 177.9 93.5 13.2 19.2 12.5 86.2 29.8 15.0 4.8 11.4 66.7 36.6 7.2 24.7 11.1 45.0 94.6 16.5 21.8 38.9 88.7 20.3 26.7 10.3 5.2 113.7 103.7 17.3 46.1 44.1 9.5 13.0 12.7 56.5 10.3 24.9 219.7 23.4 21.0 12.1 40.6 9.7 10.5 12.0 12.8 19.5 7.6 7.9 10.4 22.6 9.2 44.6 6.6 11.8 15.2 20.5 25.2 22.4 22.4 21.4 27.7 30.9 30.1 25.0 22.7 26.3 21.0 107.4 44.8 23.6 184.1 22.1 194.4 380.3 92.1 63.7 4.7 90.2 67.4 1844.2 62.9 82.9 49.7 31.3 13.7 18.5 180.0 13.7 95.0 19.2 68.7 11.8 117.2 109.4 27.6 4.9 95.1 96.5 97.8 84.6 108.7 52.0 29.1 137.8 207.0 38.8 1.7 20.7 107.4 36.7 60.6 75.3 9.1 41.3 59.8 62.2 104.0 41.6 86.2 12.3 181.5 43.1 139.2 166.8 66.5 23.2 300.7 117.5 73.6 70.0 35.8 78.9 96.7 134.7 23.8 34.4 107.3 157.0 23.8 31.1 6.8 74.0 217.5 PDLIM7 ENIGMA ENSG00000196923 "PDZ and LIM domain 7" Q9NR12 5 177483394-177497606 "Predicted intracellular proteins" "Differentiation, Osteogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 570.3;skeletal muscle: 661.5" "Cell type enhanced" "Detected in many" "Ductal cells: 164.8;Exocrine glandular cells: 242.1;Pancreatic endocrine cells: 320.1;Peritubular cells: 223.0;Sertoli cells: 164.3;Smooth muscle cells: 157.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 177.1;eosinophil: 121.2;neutrophil: 438.7" "Lineage enriched" "Detected in all" 9 "granulocytes: 438.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018794, HPA048815" Approved Enhanced "Actin filaments,Focal adhesion sites" NA NA 1700000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Actin filaments, Focal adhesion sites" "HPA018794: AB_1855155, HPA048815: AB_2680530" "unprognostic (7.70e-3)" "unprognostic (3.75e-2)" "unprognostic (9.27e-3)" "prognostic unfavorable (5.45e-4)" "unprognostic (1.40e-1)" "unprognostic (3.48e-2)" "unprognostic (9.18e-3)" "prognostic unfavorable (4.07e-4)" "unprognostic (5.01e-2)" "unprognostic (3.10e-1)" "unprognostic (7.24e-2)" "unprognostic (1.88e-1)" "prognostic unfavorable (6.19e-10)" "unprognostic (6.72e-3)" "unprognostic (3.02e-1)" "unprognostic (1.93e-1)" "unprognostic (3.68e-2)" 74.3 26.7 23.0 74.5 27.2 50.3 58.2 18.8 39.8 183.7 30.2 570.3 31.5 489.5 28.8 64.5 236.0 45.0 79.9 22.3 27.6 52.8 16.0 84.7 15.1 23.9 23.4 94.2 15.1 9.6 66.3 33.2 24.9 245.3 24.9 5.7 42.3 200.7 661.5 38.0 111.7 177.6 20.8 84.5 156.1 37.6 28.5 11.5 37.1 70.5 7.6 315.4 125.0 20.5 115.8 25.8 120.7 89.4 32.5 59.9 118.9 232.4 132.8 128.9 89.0 50.9 109.6 20.4 220.4 156.4 69.5 59.5 19.7 160.6 30.3 27.5 27.6 73.6 92.2 52.6 83.6 38.8 237.3 132.0 29.1 115.6 51.5 191.9 85.4 18.3 52.4 15.3 102.5 103.9 7.0 88.6 75.7 23.2 108.8 144.4 101.3 14.0 89.1 29.6 17.5 35.8 91.5 16.9 44.6 39.9 24.3 31.3 292.9 153.8 168.1 60.5 211.7 4.0 4.7 24.1 73.3 44.2 35.7 177.1 46.7 121.2 5.3 22.9 6.3 9.6 3.1 7.2 26.7 5.3 3.0 4.0 438.7 2.3 29.3 1.9 7.0 23.9 23.0 27.2 18.8 39.8 22.3 27.6 23.9 23.4 24.9 20.8 28.5 20.5 36.6 0.0 0.6 11.1 7.5 14.5 47.1 106.8 6.2 6.3 7.6 65.3 21.0 4.3 20.9 25.8 14.6 12.5 4.4 5.5 25.4 164.8 27.0 7.5 44.8 51.0 3.5 9.4 13.9 242.1 53.3 65.0 9.7 7.3 17.2 18.6 51.0 1.6 64.0 8.4 7.4 2.1 36.7 16.6 18.3 49.3 44.7 44.9 10.6 5.6 31.0 16.2 1.0 2.0 1.7 320.1 33.6 223.0 3.2 30.4 1.0 15.7 13.2 22.6 164.3 24.6 157.7 11.6 38.7 12.2 15.8 14.1 10.8 18.2 3.1 25.3 PLAAT1 "A-C1, H-REV107, HRASLS, HRASLS1, PLA/AT1, PLAAT-1" ENSG00000127252 "Phospholipase A and acyltransferase 1" Q9HDD0 3 193241128-193277738 "Enzymes, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "skeletal muscle: 90.1;testis: 73.6;tongue: 44.5" "Cell type enriched" "Detected in some" 11 "Cardiomyocytes: 12.5" "Cancer enhanced" "Detected in many" "glioma: 8.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 12.9;NTERA-2: 11.0;PC-3: 23.8;RH-30: 10.7;SCLC-21H: 22.0;U-2 OS: 13.3;U-251 MG: 18.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051179 Uncertain Approved "Focal adhesion sites,Cytosol" No No "Cluster 9: Neutrophils - Innate immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 54: Cardiomyocytes - Muscle contraction" "Focal adhesion sites" Cytosol "HPA051179: AB_2681375" "unprognostic (3.01e-2)" "unprognostic (4.21e-2)" "unprognostic (7.93e-3)" "unprognostic (4.82e-3)" "unprognostic (2.79e-1)" "unprognostic (1.87e-1)" "unprognostic (9.97e-3)" "unprognostic (9.68e-3)" "unprognostic (1.84e-1)" "unprognostic (3.55e-1)" "unprognostic (1.77e-4)" "unprognostic (5.09e-2)" "unprognostic (1.38e-5)" "unprognostic (1.61e-2)" "prognostic favorable (4.36e-4)" "unprognostic (2.98e-3)" "unprognostic (1.13e-2)" 0.9 2.5 4.6 0.2 4.9 0.1 1.8 3.5 6.0 0.4 0.8 0.6 0.0 0.9 5.9 6.5 0.5 0.2 9.3 5.1 6.0 0.7 0.1 0.2 0.0 4.5 4.3 0.2 1.4 2.1 2.2 0.1 4.2 0.1 0.1 9.0 2.0 0.7 90.1 3.3 0.3 1.3 2.3 0.2 0.8 73.6 3.9 2.2 7.0 44.5 0.3 0.3 0.4 4.5 0.0 0.1 2.6 0.0 0.0 0.0 0.0 0.2 0.0 2.3 0.4 0.0 0.1 0.0 0.2 0.0 5.3 0.0 12.9 0.4 0.6 0.0 5.6 6.9 0.0 0.0 0.0 0.0 0.1 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 11.0 0.4 23.8 0.0 10.7 0.0 3.7 0.0 22.0 4.1 1.5 3.3 0.0 2.1 6.5 0.1 0.1 0.0 13.3 0.0 18.6 0.1 0.0 0.0 7.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 2.4 4.6 4.9 3.5 6.0 5.1 6.0 4.5 4.3 4.2 2.3 3.9 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 PLEC "EBS1, PCN, PLEC1, PLTN" ENSG00000178209 Plectin Q15149 8 143915153-143976734 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Cancer-related genes, Disease variant, Epidermolysis bullosa, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 256.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 257.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "PC-3: 384.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003847, HPA025967, HPA029906" Enhanced Supported "Intermediate filaments,Focal adhesion sites,Cytosol" NA NA 7400000 "Cluster 39: Non-specific - mRNA processing" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Intermediate filaments, Cytosol" "Focal adhesion sites" "CAB003847: AB_562198, HPA025967: AB_10601671, HPA029906: AB_10602279" "unprognostic (1.02e-1)" "unprognostic (1.37e-3)" "prognostic unfavorable (4.29e-4)" "unprognostic (2.09e-2)" "unprognostic (1.04e-1)" "unprognostic (1.05e-2)" "unprognostic (1.76e-3)" "prognostic unfavorable (5.33e-4)" "unprognostic (1.72e-3)" "unprognostic (1.13e-2)" "unprognostic (2.85e-3)" "unprognostic (5.48e-2)" "prognostic unfavorable (7.98e-6)" "unprognostic (2.30e-1)" "unprognostic (4.04e-2)" "unprognostic (6.58e-2)" "unprognostic (5.58e-3)" 41.8 30.9 44.2 22.6 25.4 43.2 37.9 20.4 39.7 57.4 6.7 58.0 21.1 55.2 8.5 59.7 47.9 22.8 78.9 42.2 31.0 30.0 31.3 49.2 22.1 48.5 28.6 47.1 27.6 8.1 33.0 18.3 30.8 49.5 13.0 3.9 42.9 19.8 256.5 83.1 53.8 27.7 28.8 46.1 49.1 15.3 43.2 14.4 25.7 74.7 15.8 56.5 55.7 25.9 92.6 247.3 15.1 20.3 31.6 66.9 62.8 125.9 49.3 32.3 18.7 39.2 88.5 8.9 82.9 179.7 54.6 98.9 10.3 162.6 13.3 58.7 10.0 24.9 268.0 34.0 54.0 9.6 26.1 71.8 40.7 84.6 164.2 28.3 43.0 7.6 16.2 25.9 39.7 175.3 5.1 19.8 12.2 29.4 384.8 1.8 46.2 24.6 67.7 147.7 16.6 16.8 217.4 50.0 21.1 21.7 55.7 12.4 125.7 117.8 217.3 110.6 155.1 4.7 3.7 6.3 106.9 15.2 176.2 0.0 2.0 0.1 0.6 1.7 1.3 0.6 1.2 0.9 1.6 0.6 0.8 0.5 0.4 0.3 1.2 1.3 1.4 2.0 44.2 25.4 20.4 39.7 42.2 31.0 48.5 28.6 30.8 28.8 43.2 25.9 83.8 28.9 15.6 78.0 27.0 108.0 53.1 62.9 50.7 15.8 29.4 27.9 39.3 31.5 42.9 40.5 25.0 34.4 27.1 257.8 0.0 39.3 1.4 39.4 52.6 68.2 32.2 11.8 47.3 20.2 32.1 45.7 170.2 57.3 8.2 14.4 63.1 69.0 35.2 30.3 36.5 79.9 10.2 67.5 100.4 5.0 44.4 61.2 33.8 27.2 54.9 11.2 15.5 14.6 3.4 157.8 194.1 74.9 39.3 144.9 124.9 4.6 50.3 10.8 6.6 42.1 61.5 1.2 7.1 72.2 76.7 69.0 35.0 18.8 61.6 121.0 PNMA1 MA1 ENSG00000176903 "PNMA family member 1" Q8ND90 14 73711783-73714384 "Predicted intracellular proteins" "Tumor antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 84.2;Peritubular cells: 84.7;Spermatocytes: 87.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA003817, HPA015007" Enhanced Supported "Nucleoplasm,Focal adhesion sites,Cytosol" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 57: Non-specific - Angiogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "Nucleoplasm, Focal adhesion sites" "HPA003817: AB_1079646, HPA015007: AB_1855502" "unprognostic (2.82e-2)" "unprognostic (3.26e-1)" "unprognostic (9.50e-2)" "unprognostic (1.10e-1)" "unprognostic (2.96e-1)" "prognostic unfavorable (7.49e-5)" "prognostic unfavorable (3.00e-5)" "unprognostic (2.90e-1)" "unprognostic (5.35e-2)" "unprognostic (3.63e-1)" "unprognostic (5.58e-2)" "unprognostic (4.58e-2)" "unprognostic (1.67e-3)" "unprognostic (2.04e-3)" "unprognostic (4.17e-2)" "unprognostic (2.23e-3)" "prognostic unfavorable (4.51e-5)" 35.5 30.2 75.0 20.3 80.5 8.8 20.6 55.5 85.6 37.6 34.7 56.7 13.9 46.3 54.6 23.4 38.1 24.6 23.3 77.3 90.0 27.8 4.9 15.5 16.4 62.1 62.5 53.4 9.2 8.0 53.1 21.4 62.9 48.8 16.5 59.9 10.9 89.3 12.0 9.8 24.9 52.3 66.9 19.2 26.0 71.0 78.4 19.0 18.5 10.4 12.5 41.7 26.6 70.3 48.2 42.8 72.3 54.1 53.1 56.0 29.9 49.8 27.8 44.5 32.5 40.6 29.2 1.1 33.8 60.7 42.4 31.6 56.0 29.4 45.7 45.7 34.7 27.2 35.8 30.7 56.8 15.3 41.6 49.8 35.1 53.4 33.5 87.4 68.1 28.7 23.9 29.3 61.2 117.6 30.5 37.1 21.8 24.6 149.0 47.5 45.0 1.1 58.8 1.5 85.4 65.5 87.5 19.9 40.4 43.6 97.0 25.6 66.5 89.3 71.7 54.9 41.1 25.7 42.9 14.2 88.3 21.4 30.3 2.9 1.8 4.7 8.5 3.5 5.8 2.8 10.9 8.7 3.9 3.1 10.4 10.0 1.6 5.6 5.3 0.6 14.2 7.3 75.0 80.5 55.5 85.6 77.3 90.0 62.1 62.5 62.9 66.9 78.4 70.3 13.1 6.4 3.0 21.9 8.8 3.8 6.8 5.0 6.2 48.6 7.0 7.5 19.9 2.8 4.1 14.7 12.5 7.5 10.4 6.7 15.6 10.1 84.2 32.2 30.6 13.5 18.7 3.0 31.4 6.7 11.3 20.5 14.3 10.2 16.5 16.6 20.0 1.6 15.6 58.9 28.9 5.4 14.2 6.8 25.9 57.6 32.6 18.8 19.6 12.2 14.1 65.2 10.3 17.1 21.7 30.2 1.4 84.7 10.9 7.4 1.6 26.6 23.1 49.1 72.3 31.2 44.1 87.2 44.4 4.7 3.8 6.0 20.0 43.8 2.5 3.7 PPFIA1 "LIP.1, LIPRIN" ENSG00000131626 "PTPRF interacting protein alpha 1" Q13136 11 70270690-70385312 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 190.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "A-431: 261.2;SK-MEL-30: 156.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017032, HPA042271" Uncertain Supported "Focal adhesion sites,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "Focal adhesion sites" "CAB017032: , HPA042271: AB_2677923" "unprognostic (1.89e-1)" "unprognostic (1.28e-2)" "unprognostic (6.27e-2)" "unprognostic (9.92e-2)" "unprognostic (1.18e-1)" "prognostic unfavorable (5.58e-4)" "unprognostic (7.20e-3)" "unprognostic (2.20e-1)" "unprognostic (3.02e-2)" "unprognostic (5.45e-3)" "prognostic unfavorable (8.26e-4)" "unprognostic (1.14e-1)" "prognostic favorable (3.76e-4)" "unprognostic (1.09e-1)" "unprognostic (1.14e-1)" "unprognostic (1.80e-1)" "unprognostic (2.14e-2)" 26.6 14.6 17.5 16.1 18.2 20.6 17.6 16.0 19.2 13.1 22.1 18.2 14.0 17.9 13.7 16.4 12.1 22.1 14.5 15.6 15.8 16.4 15.0 19.8 15.7 25.9 21.0 15.1 15.9 18.0 13.2 24.1 20.6 12.4 15.8 14.9 13.4 14.0 31.6 18.0 16.2 17.4 17.6 15.3 13.5 26.3 20.1 15.7 23.3 26.8 14.0 17.0 12.1 25.1 261.2 30.4 31.8 22.5 33.1 20.3 34.9 30.0 24.4 40.8 26.0 66.8 22.8 25.8 39.6 27.3 39.4 38.3 30.7 28.3 35.9 15.5 21.5 19.7 34.3 24.7 33.4 26.2 22.1 24.9 46.8 53.1 44.6 31.4 27.9 21.3 33.1 19.9 37.3 30.8 19.3 17.7 19.7 59.5 34.3 20.6 80.2 22.2 20.6 32.9 31.9 21.5 45.2 59.1 156.6 36.0 37.5 31.2 30.0 38.0 29.8 54.3 32.4 24.7 15.8 37.3 28.2 20.1 43.0 0.0 1.6 1.1 0.8 1.2 1.2 1.5 1.2 1.1 1.3 1.0 0.9 0.6 5.0 0.4 3.5 1.7 1.2 0.6 17.5 18.2 16.0 19.2 15.6 15.8 25.9 21.0 20.6 17.6 20.1 25.1 33.0 25.6 53.5 114.6 19.3 27.4 26.4 14.2 30.1 39.1 32.8 24.1 27.2 20.0 25.1 18.4 31.3 44.2 14.2 39.3 11.7 21.8 190.4 28.7 44.4 31.4 26.9 24.8 57.8 20.3 13.7 33.3 25.5 45.4 8.8 94.3 20.7 25.2 25.2 33.7 52.8 19.8 16.2 35.5 28.8 97.7 27.7 40.4 21.4 38.4 28.8 71.8 17.5 47.7 56.4 36.2 24.7 25.6 23.6 36.7 19.2 22.7 27.1 45.8 19.7 45.4 30.0 60.7 61.9 36.1 33.1 74.3 22.2 42.2 25.1 37.2 PRAG1 "DKFZp761P0423, NACK, PEAK2, PRAGMIN, SgK223" ENSG00000275342 "PEAK1 related, kinase-activating pseudokinase 1" Q86YV5 8 8317736-8386439 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.0;thyroid gland: 23.2" "Cell type enhanced" "Detected in many" "Adipocytes: 45.9;Breast glandular cells: 14.1;Breast myoepithelial cells: 11.0;Hofbauer cells: 18.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 35.0" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 50.2;NTERA-2: 32.1;SuSa: 32.1" "Low region specificity" "Detected in all" "HPA011776, HPA012066" Uncertain Uncertain "Nucleoli,Focal adhesion sites" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 5: NTERA-2 - Transcription" "Cluster 7: Non-specific - Mitochondria" Nucleoli "Focal adhesion sites" "HPA011776: , HPA012066: AB_1847706" "unprognostic (7.04e-3)" "unprognostic (7.90e-2)" "unprognostic (2.32e-1)" "unprognostic (2.95e-2)" "unprognostic (1.60e-1)" "unprognostic (2.92e-1)" "unprognostic (1.05e-1)" "unprognostic (4.78e-3)" "unprognostic (2.64e-3)" "unprognostic (5.19e-2)" "unprognostic (4.95e-2)" "unprognostic (1.78e-1)" "prognostic favorable (4.81e-4)" "unprognostic (5.27e-2)" "unprognostic (1.23e-1)" "unprognostic (5.04e-2)" "unprognostic (5.22e-3)" 8.7 1.0 9.2 5.2 12.0 0.6 9.4 35.0 5.8 2.8 0.0 5.3 11.3 1.7 0.2 5.5 5.6 2.3 6.1 5.3 1.4 3.7 2.7 5.2 8.1 1.2 3.0 3.8 3.3 2.2 1.5 5.7 1.8 2.5 4.1 0.2 5.0 1.5 7.4 7.5 11.6 1.4 0.1 8.4 4.8 2.2 4.6 3.0 23.2 3.4 6.1 2.3 2.8 1.8 6.2 50.2 5.6 0.7 0.0 0.3 14.1 12.8 2.7 4.9 2.0 25.0 14.4 10.2 8.6 6.1 13.5 21.9 1.0 15.3 1.0 0.5 1.6 0.0 6.2 14.2 5.3 1.5 15.4 1.2 9.8 0.8 2.2 2.9 10.2 1.5 0.0 0.1 3.8 8.5 1.4 4.8 32.1 19.5 12.9 6.6 6.0 2.5 7.2 17.5 2.8 1.9 4.9 13.9 5.0 32.1 10.8 6.3 13.7 0.5 12.9 0.0 3.2 0.8 1.1 13.9 3.1 3.4 7.4 0.0 0.2 0.9 0.4 0.0 0.3 1.2 0.6 0.2 0.3 0.9 1.6 1.3 0.0 0.5 0.8 1.9 0.0 0.2 9.2 12.0 35.0 5.8 5.3 1.4 1.2 3.0 1.8 0.1 4.6 1.8 45.9 9.6 6.5 0.0 1.9 0.0 0.0 0.0 0.0 0.0 14.1 11.0 0.0 0.0 0.0 0.0 0.0 7.5 5.3 0.0 0.0 9.0 0.0 3.0 1.4 5.6 0.0 0.0 0.0 3.1 7.2 2.5 0.0 1.7 2.5 1.7 0.0 0.0 18.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.9 0.0 0.0 2.7 1.5 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.8 2.3 7.4 0.0 0.0 PTK2 "FADK, FAK, FAK1, PPP1R71" ENSG00000169398 "Protein tyrosine kinase 2" Q05397 8 140657900-141002216 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Angiogenesis "Developmental protein, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 295.2;Excitatory neurons: 584.9;Oligodendrocyte precursor cells: 353.9;Oligodendrocytes: 791.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001842, CAB004036, HPA029671" Approved Supported "Vesicles,Focal adhesion sites,Cytosol" NA Yes 25000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Focal adhesion sites" "Vesicles, Cytosol" "CAB004036: AB_2269034, HPA001842: AB_1855891, HPA029671: AB_10610288" "prognostic unfavorable (3.21e-4)" "unprognostic (3.86e-2)" "unprognostic (1.95e-1)" "prognostic unfavorable (9.11e-4)" "unprognostic (1.93e-1)" "unprognostic (2.28e-1)" "unprognostic (3.02e-2)" "unprognostic (1.27e-1)" "unprognostic (1.97e-1)" "unprognostic (2.96e-2)" "unprognostic (1.06e-2)" "unprognostic (2.38e-1)" "unprognostic (2.80e-2)" "unprognostic (2.94e-2)" "unprognostic (1.11e-1)" "unprognostic (1.53e-1)" "unprognostic (2.90e-2)" 51.0 40.4 83.8 19.5 115.1 6.7 42.1 62.4 99.9 40.3 51.0 37.2 25.8 37.3 49.7 25.6 34.0 32.1 36.9 84.5 77.3 42.6 30.1 39.4 25.3 79.1 87.6 33.7 32.1 53.1 21.3 74.2 81.0 34.0 35.3 35.5 39.9 41.6 38.7 29.6 29.5 37.6 67.6 22.8 32.8 38.9 86.7 11.9 38.7 39.4 25.8 43.9 34.0 154.5 52.6 81.9 111.0 40.3 45.8 48.8 71.6 50.8 70.0 46.3 45.3 35.9 42.1 31.7 111.7 65.3 65.0 60.3 66.1 116.0 69.6 0.3 30.8 70.1 44.3 50.0 62.5 0.1 31.8 33.4 55.8 58.0 81.0 121.5 139.0 44.0 72.0 0.8 62.9 91.0 0.9 0.7 43.2 113.2 90.3 46.8 60.9 1.5 97.7 117.3 43.9 54.8 79.0 25.0 52.0 97.2 59.2 1.2 84.9 45.2 85.5 54.0 58.1 0.0 0.6 3.4 58.7 0.6 62.9 1.6 3.3 0.0 0.2 1.4 0.0 5.3 0.6 0.0 4.5 6.3 4.4 1.6 1.3 4.7 0.8 6.1 0.2 3.9 83.8 115.1 62.4 99.9 84.5 77.3 79.1 87.6 81.0 67.6 86.7 154.5 71.3 32.1 33.1 295.2 20.6 33.3 70.1 36.3 64.9 55.2 29.3 23.5 29.6 32.9 32.1 55.2 60.5 37.0 8.0 23.1 23.5 27.2 68.4 29.3 43.3 54.3 25.8 8.4 584.9 23.3 53.7 37.2 37.8 46.5 9.5 84.7 37.5 15.7 8.1 67.3 263.6 23.0 30.5 15.2 15.9 38.8 23.9 19.4 24.9 159.3 3.9 40.9 0.0 353.9 791.4 43.1 23.5 21.8 1.7 82.4 29.3 25.6 33.7 55.0 98.6 32.7 128.4 88.9 65.5 42.8 25.9 33.2 3.4 67.0 24.1 87.3 PWWP2A KIAA1935 ENSG00000170234 "PWWP domain containing 2A" Q96N64 5 160061801-160119450 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 228.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046733, HPA058233" Supported "Nucleoplasm,Focal adhesion sites" NA NA "Cluster 37: B-cells - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Focal adhesion sites" "HPA046733: AB_2679777, HPA058233: AB_2683647" "unprognostic (1.03e-1)" "unprognostic (2.67e-1)" "unprognostic (5.13e-2)" "unprognostic (1.85e-1)" "unprognostic (1.18e-2)" "unprognostic (7.86e-3)" "unprognostic (1.40e-3)" "unprognostic (6.24e-2)" "unprognostic (2.42e-2)" "unprognostic (7.08e-2)" "unprognostic (7.25e-2)" "unprognostic (8.24e-3)" "prognostic unfavorable (3.70e-4)" "unprognostic (2.23e-1)" "unprognostic (3.88e-2)" "unprognostic (1.08e-1)" "prognostic favorable (3.51e-4)" 6.7 7.0 9.6 7.4 14.8 10.3 6.8 22.8 10.9 10.3 8.2 10.5 7.5 7.9 5.3 6.6 7.6 6.2 5.9 7.8 8.6 8.5 7.1 7.6 10.1 12.2 12.2 7.6 8.0 5.9 8.1 8.7 11.9 8.6 10.8 14.2 7.1 6.0 6.1 11.3 8.5 7.0 9.5 9.4 9.3 5.1 11.6 12.4 7.2 6.0 9.0 8.2 7.9 24.2 13.4 6.3 16.1 13.7 17.5 13.6 22.5 10.4 8.4 9.1 9.1 20.5 25.3 21.4 15.6 8.0 14.9 9.4 14.1 16.2 14.8 22.3 15.6 15.4 11.9 10.6 13.3 15.6 11.2 9.7 7.9 18.3 13.8 20.4 14.8 11.9 12.0 13.5 15.5 11.1 13.5 15.1 19.0 11.3 8.1 20.9 14.3 13.7 11.2 9.4 18.8 13.1 17.6 17.3 19.4 12.9 13.4 17.1 19.9 15.7 10.9 11.9 20.6 15.4 14.7 18.9 10.4 15.6 15.9 3.2 2.0 1.1 1.1 0.9 0.9 3.3 1.2 1.4 1.3 1.6 2.0 1.1 2.1 0.4 1.2 1.2 1.2 0.4 9.6 14.8 22.8 10.9 7.8 8.6 12.2 12.2 11.9 9.5 11.6 24.2 16.8 9.6 22.7 42.7 25.0 31.9 13.0 10.8 27.3 102.0 15.8 13.2 13.9 11.5 15.6 20.2 73.0 12.3 22.0 30.2 17.6 13.7 2.1 18.2 33.8 18.7 32.9 30.3 47.2 11.0 12.4 20.4 20.9 17.3 23.5 29.0 18.2 8.8 9.2 94.2 61.8 25.9 20.3 13.7 17.6 3.8 55.9 16.9 10.6 52.5 25.7 28.8 22.6 92.0 228.5 16.5 17.8 38.4 19.5 19.4 11.2 7.2 14.4 57.6 26.3 23.5 25.1 20.4 22.0 18.3 25.9 9.3 23.8 34.0 25.2 11.2 PXN ENSG00000089159 Paxillin P49023 12 120210439-120265771 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 152.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 169.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003841, HPA051309" Supported Enhanced "Focal adhesion sites,Centrosome,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Focal adhesion sites" "Centrosome, Cytosol" "CAB003841: AB_562188, HPA051309: AB_2681436" "unprognostic (4.00e-2)" "unprognostic (1.94e-2)" "unprognostic (3.51e-2)" "unprognostic (3.55e-3)" "prognostic unfavorable (1.09e-4)" "prognostic unfavorable (3.72e-5)" "prognostic unfavorable (7.12e-5)" "prognostic unfavorable (1.73e-4)" "unprognostic (3.12e-2)" "unprognostic (9.19e-3)" "unprognostic (2.66e-2)" "unprognostic (1.73e-1)" "unprognostic (2.12e-2)" "unprognostic (3.35e-2)" "unprognostic (2.09e-1)" "unprognostic (1.98e-1)" "unprognostic (2.75e-2)" 83.1 60.9 28.7 49.1 30.8 81.4 74.4 27.6 30.5 64.5 33.7 69.0 55.7 56.3 18.7 30.9 72.3 38.2 84.2 28.0 28.5 70.2 29.5 84.6 29.3 37.1 30.8 28.5 34.5 27.8 29.5 73.3 30.3 58.9 49.9 61.8 49.4 40.6 119.2 45.6 61.1 44.5 31.8 72.5 47.5 26.5 36.6 25.9 58.1 46.1 18.4 75.8 53.2 29.2 182.4 87.5 31.3 30.1 60.4 158.1 206.1 151.8 128.6 118.9 61.5 102.5 108.9 12.2 94.6 154.9 115.1 126.0 21.7 272.0 93.0 9.9 18.6 2.3 63.8 37.9 86.8 2.7 3.6 76.5 176.2 125.3 143.9 139.7 211.6 32.2 32.4 19.5 239.3 119.6 11.1 4.1 43.5 77.1 300.8 26.2 51.0 10.8 121.4 171.9 48.7 14.5 133.2 40.3 81.7 72.1 96.1 14.8 289.9 78.9 86.7 103.6 183.9 20.4 12.3 4.6 228.9 27.0 159.2 40.8 44.2 49.2 84.5 15.7 45.3 1.7 38.4 56.0 26.2 1.1 29.5 40.3 169.6 51.8 0.8 4.1 31.4 60.6 28.7 30.8 27.6 30.5 28.0 28.5 37.1 30.8 30.3 31.8 36.6 29.2 93.6 57.7 27.9 11.8 3.0 42.3 40.6 32.8 15.4 7.8 20.3 22.9 14.7 22.8 33.3 42.3 33.3 40.8 61.6 83.1 19.6 31.6 2.1 26.0 16.7 71.0 54.6 6.1 5.1 40.2 152.4 29.7 37.2 28.8 18.3 6.2 62.2 17.2 34.2 11.8 7.7 52.7 24.4 42.3 23.7 2.8 24.2 23.5 26.6 19.7 36.8 9.1 99.9 13.0 9.2 84.8 51.6 18.8 14.5 41.7 56.6 14.6 40.0 33.6 6.6 16.7 12.1 3.5 9.1 8.1 19.5 25.0 34.4 11.3 35.8 42.6 RAB24 ENSG00000169228 "RAB24, member RAS oncogene family" Q969Q5 5 177301198-177303744 "Predicted intracellular proteins" "Autophagy, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 55.2;Plasma cells: 71.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 125.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034945 Uncertain "Focal adhesion sites" No No "Cluster 45: Eosinophils - Innate immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 59: Non-specific - Transcription" "Focal adhesion sites" "HPA034945: " "unprognostic (1.03e-2)" "unprognostic (6.81e-2)" "unprognostic (3.05e-2)" "unprognostic (1.59e-1)" "unprognostic (7.86e-2)" "prognostic favorable (6.22e-4)" "prognostic unfavorable (7.56e-5)" "unprognostic (1.28e-1)" "unprognostic (1.78e-2)" "unprognostic (9.66e-2)" "unprognostic (1.43e-3)" "unprognostic (2.79e-2)" "prognostic unfavorable (2.54e-7)" "unprognostic (3.97e-2)" "unprognostic (1.22e-1)" "unprognostic (2.75e-1)" "unprognostic (1.12e-2)" 22.0 38.9 30.1 20.0 30.1 25.9 24.3 25.8 32.6 31.2 32.4 24.0 13.8 20.0 22.1 42.4 20.2 11.5 23.5 30.3 31.9 32.8 30.5 27.1 15.7 30.1 26.4 27.0 59.7 17.8 48.6 12.0 29.9 31.1 10.5 11.6 34.3 12.5 30.3 42.2 24.5 11.7 26.3 53.7 22.2 11.4 29.6 11.2 24.1 17.4 20.6 23.5 32.3 29.6 6.9 17.7 13.0 25.3 20.8 18.0 19.5 19.8 28.6 27.8 33.7 20.9 8.8 7.2 24.2 18.5 30.7 4.9 17.7 24.8 15.7 125.9 9.8 25.2 17.4 18.6 43.2 15.6 21.3 30.4 20.2 29.9 21.0 41.4 17.3 21.4 18.0 42.6 20.1 26.2 5.7 38.3 8.0 15.2 17.8 3.6 18.5 28.0 19.1 12.6 14.1 20.1 6.8 13.1 59.6 15.9 23.0 41.0 16.2 8.5 14.2 19.8 19.1 31.4 15.9 9.8 16.5 24.3 17.9 42.6 87.1 166.7 19.0 185.2 17.7 33.2 10.3 16.6 60.1 29.0 10.9 16.6 137.3 37.4 183.6 13.6 9.3 48.4 30.1 30.1 25.8 32.6 30.3 31.9 30.1 26.4 29.9 26.3 29.6 29.6 6.3 3.2 7.1 31.0 33.7 5.4 1.6 16.3 55.2 3.7 12.1 8.4 2.4 1.5 12.9 1.8 2.1 7.6 7.3 28.5 3.9 24.5 0.6 2.4 3.9 5.9 18.0 12.6 42.7 20.1 6.3 10.8 31.1 3.2 12.0 1.3 5.3 1.7 4.3 13.5 45.1 12.8 6.1 8.8 6.9 0.6 5.0 37.7 3.6 10.3 11.1 2.0 9.2 14.6 15.6 18.9 27.7 1.2 71.1 1.9 26.0 6.9 5.5 4.2 0.0 2.4 8.0 2.2 3.6 43.8 6.0 30.6 15.4 2.2 13.3 2.0 RAET1E "bA350J20.7, LETAL, ULBP4" ENSG00000164520 "Retinoic acid early transcript 1E" Q8TD07 6 149883375-149898102 "Predicted intracellular proteins, Predicted membrane proteins" Immunity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 21.9;esophagus: 62.8;skin 1: 21.6;vagina: 27.5" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 12.4;Early spermatids: 10.0;Late spermatids: 5.6;Respiratory ciliated cells: 14.6;Squamous epithelial cells: 17.2;Suprabasal keratinocytes: 6.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 3.9" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HBEC3-KT: 19.6;HeLa: 24.4;hTCEpi: 19.1;SiHa: 9.9;U-87 MG: 7.7" HPA054022 Supported "Focal adhesion sites,Cytosol" "Intracellular and membrane" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 20: HeLa - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Focal adhesion sites" Cytosol "HPA054022: AB_2797250" "unprognostic (1.67e-2)" "unprognostic (2.10e-1)" "unprognostic (3.49e-3)" "unprognostic (1.26e-1)" "unprognostic (1.36e-1)" "unprognostic (2.71e-2)" "unprognostic (1.36e-3)" "unprognostic (4.80e-4)" "unprognostic (1.11e-1)" "unprognostic (3.39e-1)" "unprognostic (1.02e-1)" "unprognostic (1.69e-1)" "unprognostic (7.47e-5)" "unprognostic (2.41e-2)" "unprognostic (3.18e-2)" "unprognostic (3.17e-2)" "unprognostic (1.06e-1)" 3.7 0.8 0.6 0.1 0.4 0.1 1.9 1.0 0.7 21.9 0.8 0.2 0.1 0.3 0.0 62.8 0.8 0.1 0.5 0.5 0.5 2.2 0.1 0.3 0.1 0.4 0.3 0.1 0.1 0.0 0.2 0.5 0.5 0.3 0.3 0.1 12.9 0.3 1.6 21.6 0.1 0.5 0.1 0.9 0.3 0.4 0.4 0.1 0.3 0.2 11.6 1.9 27.5 0.5 1.8 1.0 0.0 0.0 0.2 1.3 0.0 0.1 0.9 0.1 0.3 0.0 4.3 0.0 2.6 4.4 1.4 1.7 0.0 19.6 0.2 0.3 0.0 0.1 24.4 0.0 0.0 0.0 0.0 0.4 19.1 1.0 3.9 0.4 0.1 0.1 0.0 1.3 0.8 0.0 0.0 0.0 0.1 0.3 0.8 0.0 0.0 0.3 0.4 0.9 0.2 0.0 9.9 1.5 0.0 0.0 1.2 0.0 1.8 0.8 0.3 0.2 0.9 0.0 0.0 0.0 7.7 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.4 1.0 0.7 0.5 0.5 0.4 0.3 0.5 0.1 0.4 0.5 1.0 0.0 0.0 0.3 0.0 2.2 1.1 12.4 1.8 0.6 0.3 0.6 0.3 1.5 3.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.0 2.5 0.1 1.0 0.0 0.0 0.9 0.0 0.0 2.0 0.0 0.1 0.0 0.0 0.7 0.0 0.1 0.0 1.1 0.1 0.0 0.0 0.3 5.6 0.0 0.0 0.0 1.9 0.0 0.2 0.0 0.5 1.1 0.4 0.0 0.0 0.0 0.2 0.0 0.0 14.6 0.4 0.0 0.3 0.4 0.0 0.2 17.2 6.5 0.0 0.2 0.1 0.2 1.6 RALA RAL ENSG00000006451 "RAS like proto-oncogene A" P11233 7 39623565-39708120 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Cell cycle, Cell division, Exocytosis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 292.4;Pancreatic endocrine cells: 411.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 302.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047037, HPA065232" Approved Supported "Plasma membrane,Focal adhesion sites" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 10: Non-specific - Unknown function" "Plasma membrane" "Focal adhesion sites" "HPA047037: , HPA065232: AB_2685440" "unprognostic (1.20e-3)" "unprognostic (1.03e-2)" "unprognostic (2.91e-1)" "unprognostic (7.73e-3)" "unprognostic (1.98e-2)" "unprognostic (9.14e-2)" "prognostic unfavorable (5.32e-5)" "unprognostic (7.71e-2)" "unprognostic (2.17e-1)" "prognostic favorable (7.46e-4)" "prognostic unfavorable (6.30e-4)" "unprognostic (3.32e-1)" "unprognostic (4.95e-3)" "unprognostic (5.38e-2)" "unprognostic (7.15e-2)" "unprognostic (2.79e-1)" "unprognostic (2.95e-2)" 27.8 32.1 32.4 20.7 35.5 7.4 23.8 35.8 37.3 23.0 30.2 30.9 32.6 20.4 20.1 54.0 19.6 26.8 17.6 33.7 34.3 20.6 21.4 41.8 21.4 37.0 35.7 22.2 16.0 22.6 10.5 32.5 36.4 15.4 31.6 13.0 19.8 15.8 25.8 26.9 30.9 21.1 37.7 18.8 33.8 12.7 34.9 25.5 17.4 19.1 35.2 23.5 22.0 39.8 81.0 18.3 44.1 38.6 81.7 67.6 30.0 69.7 99.7 61.8 67.9 46.1 39.0 41.5 25.5 54.1 58.1 81.5 62.5 45.0 105.5 40.2 29.6 32.4 28.1 34.1 132.1 56.9 43.8 53.7 54.0 110.0 155.4 76.7 302.4 39.7 65.9 27.0 63.2 26.3 40.3 66.7 123.0 88.0 35.9 49.4 40.2 36.3 63.1 37.3 78.0 75.6 42.8 67.7 49.4 78.7 63.5 60.9 98.0 36.4 32.4 46.3 50.7 47.6 39.1 50.3 40.5 58.0 67.2 38.3 13.5 15.7 12.5 15.6 15.7 15.8 20.1 16.2 22.6 18.0 25.6 22.9 6.1 23.2 12.6 14.5 28.1 15.9 32.4 35.5 35.8 37.3 33.7 34.3 37.0 35.7 36.4 37.7 34.9 39.8 66.5 83.3 38.1 25.5 40.5 90.1 37.3 75.1 41.5 14.6 41.3 63.5 37.3 40.0 50.3 23.9 6.2 52.1 28.4 80.1 21.5 165.4 98.2 56.5 64.8 121.5 47.8 35.1 47.6 122.0 92.5 52.4 42.3 99.9 31.7 41.8 75.0 27.8 101.9 11.8 48.4 53.1 144.5 33.0 292.4 17.4 47.8 73.0 30.2 44.0 97.0 37.3 23.7 39.2 37.0 411.0 73.8 69.6 48.6 61.0 70.8 38.6 36.6 16.6 32.9 26.5 131.9 59.1 71.6 113.4 109.4 62.0 37.0 53.9 58.7 64.5 RAPGEF4 "cAMP-GEFII, CGEF2" ENSG00000091428 "Rap guanine nucleotide exchange factor 4" Q8WZA2 2 172735274-173052893 "Predicted intracellular proteins" Exocytosis "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 142.3" "Group enriched" "Detected in many" 7 "Excitatory neurons: 441.1;Inhibitory neurons: 416.6;Microglial cells: 142.4;Oligodendrocyte precursor cells: 303.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 21.5;SCLC-21H: 8.3;U-266/70: 11.0;U-266/84: 23.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004388, HPA028968" Approved Approved "Focal adhesion sites" NA NA "Cluster 65: Brain - Ion transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Focal adhesion sites" "CAB004388: AB_670916, HPA028968: AB_2672846" "unprognostic (1.87e-1)" "unprognostic (4.22e-2)" "unprognostic (1.31e-1)" "unprognostic (2.98e-3)" "unprognostic (4.53e-2)" "unprognostic (1.20e-2)" "unprognostic (4.45e-2)" "unprognostic (1.80e-1)" "unprognostic (1.16e-1)" "unprognostic (3.23e-1)" "prognostic favorable (1.32e-4)" "unprognostic (6.32e-2)" "unprognostic (1.46e-3)" "unprognostic (1.97e-2)" "unprognostic (6.18e-2)" "unprognostic (5.70e-2)" "unprognostic (2.93e-1)" 5.3 45.6 105.0 1.8 113.1 0.2 6.8 69.8 141.6 6.1 49.1 2.1 2.4 5.6 3.1 2.6 3.4 4.7 7.5 142.3 77.7 5.3 34.6 11.4 2.0 61.2 75.0 13.1 4.5 4.0 6.2 2.6 60.8 4.1 1.6 18.8 2.4 3.3 1.5 14.9 2.3 5.4 55.7 0.6 7.7 4.7 128.3 2.2 5.5 1.7 2.0 5.3 3.2 121.9 0.1 0.2 3.2 0.5 0.1 0.3 0.1 1.1 0.7 0.1 0.3 0.0 3.7 0.0 0.2 0.0 0.2 0.7 2.8 0.7 0.3 0.2 5.9 0.6 2.8 0.0 0.0 3.2 0.9 0.1 0.9 0.0 0.0 3.2 3.5 1.6 0.0 21.5 0.1 0.1 0.2 0.2 0.4 1.8 0.4 0.1 0.7 0.0 0.0 6.6 8.3 3.0 0.1 0.1 1.1 1.6 0.1 0.1 1.0 0.1 0.3 0.0 0.3 11.0 23.0 0.0 0.4 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 105.0 113.1 69.8 141.6 142.3 77.7 61.2 75.0 60.8 55.7 128.3 121.9 14.7 3.2 2.8 23.2 1.9 6.1 1.1 0.1 2.8 3.5 5.5 3.9 6.9 0.0 0.0 0.0 45.9 0.1 0.1 0.0 0.0 1.7 2.5 1.2 0.2 32.4 7.8 0.0 441.1 2.7 0.1 4.8 3.1 0.9 0.0 3.3 23.9 11.8 0.1 1.7 416.6 0.5 0.0 1.2 2.1 1.4 4.4 0.2 3.6 142.4 0.0 1.3 0.0 303.1 28.4 1.5 0.1 1.5 1.6 0.5 0.0 0.0 0.0 9.2 0.0 0.4 1.2 0.7 4.1 1.6 3.8 0.1 0.6 4.2 0.1 0.7 RASAL2 nGAP ENSG00000075391 "RAS protein activator like 2" Q9UJF2 1 178094104-178484147 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 28.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 505.8;Inhibitory neurons: 398.4;Microglial cells: 271.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-HME1: 54.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018805, HPA020453" Enhanced Approved "Plasma membrane,Focal adhesion sites" NA Yes "Cluster 77: Retina - Visual perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Focal adhesion sites" "HPA018805: AB_1856085, HPA020453: AB_1856086" "unprognostic (5.55e-3)" "unprognostic (6.49e-2)" "unprognostic (2.65e-1)" "unprognostic (6.33e-2)" "unprognostic (3.40e-2)" "unprognostic (5.59e-2)" "unprognostic (5.91e-2)" "unprognostic (1.72e-2)" "unprognostic (2.91e-1)" "unprognostic (2.92e-2)" "unprognostic (3.16e-3)" "unprognostic (2.03e-1)" "unprognostic (1.06e-2)" "unprognostic (4.98e-2)" "unprognostic (2.45e-1)" "unprognostic (8.36e-2)" "prognostic unfavorable (2.05e-4)" 10.3 3.6 1.7 2.8 3.2 0.6 8.0 0.0 7.4 7.3 0.1 4.2 2.7 6.1 3.6 17.0 5.5 7.5 13.6 4.3 0.8 5.8 3.0 9.4 1.8 0.0 1.0 3.6 4.6 4.6 5.9 9.4 0.0 5.0 4.4 28.9 6.6 4.4 4.6 7.0 3.4 6.6 0.0 3.2 3.7 8.9 5.1 1.8 5.3 10.0 2.9 5.0 10.5 2.4 30.9 8.9 12.1 4.2 8.6 11.6 17.3 13.2 13.6 11.7 8.5 14.8 15.6 0.0 23.0 13.2 19.7 25.2 10.2 23.0 10.7 0.0 5.0 0.0 9.8 7.1 10.0 4.7 0.5 35.1 5.2 13.4 54.1 13.7 10.3 0.0 1.0 0.0 16.5 3.2 0.0 4.2 10.1 6.4 1.8 0.1 5.2 0.0 7.2 3.6 8.8 4.4 10.9 9.5 9.0 10.8 10.4 5.5 18.9 15.1 15.7 17.2 21.0 6.5 0.1 0.1 13.3 2.4 11.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.7 3.2 0.0 7.4 4.3 0.8 0.0 1.0 0.0 0.0 5.1 2.4 99.8 76.9 12.9 47.3 1.0 15.9 10.0 15.7 8.0 50.7 17.8 11.7 37.4 17.2 18.2 16.5 152.2 15.0 1.0 9.0 5.9 21.8 17.4 33.6 43.0 66.2 34.1 0.0 505.8 12.5 16.4 18.4 17.9 27.6 7.6 19.0 35.3 6.7 16.8 84.1 398.4 15.7 6.1 4.5 21.6 7.3 19.6 16.5 3.6 271.7 8.5 24.7 0.0 154.3 101.3 33.6 5.2 23.0 2.9 32.6 4.9 6.6 34.7 175.5 65.7 22.7 56.9 40.5 34.5 17.8 24.2 41.9 2.3 8.3 12.6 38.2 REXO2 "CGI-114, DKFZP566E144, SFN" ENSG00000076043 "RNA exonuclease 2" Q9Y3B8 11 114439435-114450279 "Predicted intracellular proteins" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038450, HPA038451" Enhanced Supported "Nucleoli,Focal adhesion sites,Mitochondria" NA NA 340000 "Cluster 6: Non-specific - Transcription" "Cluster 46: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" Mitochondria "Nucleoli, Focal adhesion sites" "HPA038450: AB_10672516, HPA038451: AB_10697391" "unprognostic (3.26e-3)" "unprognostic (2.36e-2)" "prognostic favorable (6.51e-4)" "unprognostic (6.84e-3)" "unprognostic (5.80e-3)" "unprognostic (1.06e-1)" "unprognostic (1.40e-3)" "unprognostic (1.78e-1)" "unprognostic (8.18e-3)" "unprognostic (2.49e-2)" "unprognostic (2.17e-3)" "unprognostic (1.02e-1)" "unprognostic (1.73e-2)" "unprognostic (6.75e-2)" "unprognostic (1.23e-1)" "unprognostic (7.69e-2)" "prognostic unfavorable (6.70e-4)" 51.1 57.2 23.5 40.3 25.9 55.0 57.1 26.3 31.5 73.4 28.6 80.4 24.3 71.5 46.5 65.8 38.1 47.8 140.3 24.0 29.5 102.5 50.2 42.0 32.5 30.3 28.1 69.0 45.5 154.5 32.5 56.9 29.7 72.5 47.2 9.2 115.3 58.0 40.8 50.5 33.1 106.7 26.6 44.8 65.4 53.5 25.7 30.4 36.5 40.5 37.1 68.3 64.4 29.9 159.3 92.7 32.1 88.4 254.6 268.7 81.9 266.3 192.9 122.6 155.4 244.9 261.2 88.8 258.2 220.8 185.4 97.4 74.1 219.5 201.5 86.9 61.3 98.1 136.0 144.7 339.2 72.3 29.5 190.8 206.0 157.4 163.7 214.1 223.1 84.7 183.9 48.6 278.5 38.7 49.4 84.0 102.3 119.1 160.3 45.7 112.1 317.1 177.0 126.9 59.8 38.5 122.7 86.7 110.8 134.8 184.9 35.6 231.4 162.5 194.2 124.0 161.6 39.7 52.4 146.3 111.3 165.2 89.7 64.3 14.0 21.3 32.2 19.2 37.2 37.6 47.9 41.1 18.8 29.2 43.0 35.1 3.5 45.2 20.6 70.1 75.3 29.1 23.5 25.9 26.3 31.5 24.0 29.5 30.3 28.1 29.7 26.6 25.7 29.9 82.9 105.8 56.4 20.9 42.3 138.9 146.5 189.1 88.2 14.9 99.2 100.6 370.0 47.1 126.5 95.6 2.1 171.6 55.3 27.2 277.8 126.6 83.6 75.3 110.8 98.4 80.9 315.2 20.0 70.7 188.5 176.8 48.4 85.2 31.8 40.1 89.6 80.0 98.2 5.0 17.4 82.9 89.5 21.0 56.7 48.1 210.6 33.9 241.9 15.9 41.9 36.5 29.9 25.1 33.5 110.0 33.7 176.8 103.8 199.6 26.7 371.4 126.5 8.3 52.6 90.6 177.0 237.3 82.1 119.9 162.7 269.1 47.5 120.6 72.4 130.4 RTN4R NOGOR ENSG00000040608 "Reticulon 4 receptor" Q9BZR6 22 20241415-20283246 "Disease related genes, Human disease related genes, Predicted membrane proteins" Receptor "Disease variant, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.3;liver: 12.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 12.1;Excitatory neurons: 14.1;Muller glia cells: 11.3" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 10 "amygdala: 8.0;basal ganglia: 20.0;cerebellum: 20.9;cerebral cortex: 24.3;hippocampal formation: 12.7" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 10.8" "Lineage enriched" "Detected in many" 9 "T-cells: 10.8" "Cell line enhanced" "Detected in many" "NB-4: 38.2;REH: 53.9;SCLC-21H: 31.3;SK-MEL-30: 25.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB012443 Supported "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA 1900000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane, Focal adhesion sites" "Actin filaments" "CAB012443: " "unprognostic (1.28e-1)" "unprognostic (1.28e-2)" "unprognostic (8.29e-2)" "unprognostic (6.58e-2)" "unprognostic (3.49e-1)" "prognostic unfavorable (7.73e-4)" "unprognostic (2.19e-1)" "unprognostic (1.56e-1)" "unprognostic (3.44e-1)" "unprognostic (8.90e-3)" "unprognostic (1.21e-2)" "unprognostic (9.89e-2)" "unprognostic (1.80e-2)" "unprognostic (1.34e-2)" "unprognostic (1.30e-1)" "unprognostic (5.02e-2)" "unprognostic (3.07e-1)" 1.6 2.6 8.0 0.5 20.0 0.6 1.0 20.9 24.3 3.6 0.0 1.6 2.2 5.1 0.0 3.5 1.9 0.1 2.7 12.7 0.0 2.1 12.8 2.2 0.4 0.5 0.0 2.4 3.7 0.4 4.9 0.4 0.3 1.5 0.1 0.6 2.0 0.4 0.6 7.9 2.1 0.2 0.0 8.5 1.8 1.9 0.4 0.8 3.5 0.2 0.2 0.5 2.8 1.8 7.9 3.8 2.3 5.5 0.0 0.0 1.2 0.8 0.0 0.6 0.3 6.0 2.2 0.4 2.5 0.1 3.7 12.8 1.4 3.2 0.0 0.2 13.4 0.1 3.2 0.9 1.3 0.3 0.4 0.0 4.1 0.0 0.3 0.0 0.0 3.7 0.4 0.3 0.0 11.0 4.1 38.2 8.7 2.3 6.7 53.9 0.0 0.4 0.5 3.3 31.3 5.0 3.7 2.7 25.9 0.5 3.1 1.1 0.0 0.5 14.2 0.1 0.2 0.1 1.0 0.9 0.4 7.8 0.1 0.0 0.0 0.0 4.6 0.0 10.8 0.0 4.0 4.6 0.2 0.1 2.4 5.1 0.0 0.8 0.0 1.2 3.0 1.7 8.0 20.0 20.9 24.3 12.7 0.0 0.5 0.0 0.3 0.0 0.4 1.8 1.4 3.2 0.0 7.5 0.2 5.1 4.0 1.6 1.8 12.1 2.9 2.4 2.2 0.0 0.6 0.0 4.2 0.2 1.9 3.0 0.0 2.9 2.0 1.2 4.8 2.0 0.0 0.4 14.1 4.3 7.6 1.6 0.0 1.6 0.0 0.4 1.1 3.0 1.3 6.7 2.6 2.6 0.0 0.0 0.7 0.5 0.3 1.7 1.8 2.8 0.7 11.3 2.1 2.5 2.4 3.4 0.4 0.0 0.1 3.9 0.6 0.0 0.0 4.9 0.0 0.2 1.0 0.1 1.2 2.0 5.5 0.0 2.5 0.1 2.1 3.5 SCN9A "ETHA, Nav1.7, NE-NA, NENA, PN1" ENSG00000169432 "Sodium voltage-gated channel alpha subunit 9" Q15858 2 166195185-166376001 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 21.9" "Cell type enhanced" "Detected in many" "dendritic cells: 43.2;Hofbauer cells: 67.5;Inhibitory neurons: 48.2;Langerhans cells: 42.8;Oligodendrocyte precursor cells: 133.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 16 "plasmacytoid DC: 23.6" "Lineage enriched" "Detected in single" 26 "dendritic cells: 23.6" "Cell line enhanced" "Detected in many" "BJ: 23.0;BJ hTERT+: 16.8;HHSteC: 19.0;hTERT-RPE1: 15.6" "Region enriched" "Detected in many" 5 "hypothalamus: 9.3" "Low region specificity" "Detected in many" "CAB013679, HPA061843" Uncertain Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane, Actin filaments, Focal adhesion sites" "CAB013679: , HPA061843: AB_2684625" "unprognostic (2.10e-1)" "unprognostic (2.83e-1)" "unprognostic (1.13e-1)" "unprognostic (8.98e-5)" "unprognostic (1.47e-3)" "unprognostic (9.43e-3)" "unprognostic (2.28e-2)" "unprognostic (2.24e-1)" "unprognostic (2.23e-1)" "unprognostic (3.64e-1)" "unprognostic (1.45e-1)" "unprognostic (2.27e-1)" "prognostic unfavorable (2.30e-5)" "unprognostic (1.69e-3)" "unprognostic (6.74e-2)" "unprognostic (2.46e-2)" "unprognostic (2.46e-1)" 1.7 1.7 5.3 0.9 4.2 2.0 0.6 0.1 3.4 0.6 0.0 3.2 0.5 0.2 0.1 0.5 0.4 1.2 0.4 2.9 21.9 1.7 3.9 2.0 0.6 8.2 19.4 0.3 2.0 0.1 1.5 4.3 12.0 0.3 3.1 0.7 0.4 0.4 0.2 0.7 1.8 2.4 2.2 3.1 0.4 5.1 18.2 1.6 0.3 0.6 0.4 0.5 0.5 1.7 0.0 2.5 0.1 0.0 9.6 7.9 0.0 23.0 16.8 5.2 1.7 0.5 0.1 0.0 0.0 2.8 0.2 0.1 6.5 0.6 8.6 0.0 2.1 1.7 1.8 1.9 19.0 0.1 0.0 0.6 0.2 9.1 1.7 15.6 1.1 1.2 6.1 6.6 0.8 0.0 3.6 0.0 1.9 0.1 0.6 0.8 3.3 9.0 2.4 9.5 1.0 9.5 0.0 0.1 0.3 4.8 0.3 0.0 0.1 0.0 1.5 0.1 0.4 0.1 0.1 0.0 3.2 0.0 2.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.9 0.5 0.1 23.6 0.0 0.1 5.3 4.2 0.1 3.4 2.9 21.9 8.2 19.4 12.0 2.2 18.2 1.7 0.9 12.8 23.8 0.7 1.3 1.0 0.4 0.5 0.6 0.6 0.8 0.9 2.5 8.6 4.4 5.5 0.0 0.3 43.2 9.0 3.9 23.4 2.5 0.1 0.1 5.7 33.0 4.2 15.8 31.5 0.3 2.0 0.0 0.1 3.8 18.1 13.6 9.5 67.5 0.0 48.2 19.3 10.2 1.9 42.8 3.2 1.2 11.3 3.6 2.8 1.0 2.3 0.0 133.7 0.4 12.7 7.8 0.0 1.2 0.3 14.7 11.5 2.2 0.2 0.0 7.8 1.6 1.3 0.4 0.5 0.4 1.1 0.9 4.4 12.9 0.2 SDC1 "CD138, SDC, SYND1, syndecan" ENSG00000115884 "Syndecan 1" P18827 2 20200797-20225433 "Cancer-related genes, CD markers, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 491.6;liver: 484.7;skin 1: 447.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 267.4;Hepatocytes: 603.1;Squamous epithelial cells: 246.6;Syncytiotrophoblasts: 250.8;Urothelial cells: 492.8" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 7 "midbrain: 17.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 482.2;hTCEpi: 436.6;U-251 MG: 470.0;U-266/70: 467.4;U-266/84: 1069.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "CAB002424, HPA006185, HPA067477" Enhanced Approved "Focal adhesion sites" "Secreted to blood" NA NA 63100000 3100000 "Cluster 43: B-cells - Humoral immune response" "Cluster 37: Intestine - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 22: Epithelial cell types - Mixed function" "Focal adhesion sites" "CAB002424: AB_442050, HPA006185: AB_1857705, HPA067477: " "prognostic unfavorable (2.22e-4)" "unprognostic (6.80e-3)" "unprognostic (6.80e-2)" "unprognostic (7.84e-2)" "prognostic unfavorable (5.02e-4)" "unprognostic (1.15e-1)" "unprognostic (4.02e-2)" "unprognostic (6.32e-2)" "unprognostic (1.70e-1)" "unprognostic (3.66e-1)" "unprognostic (2.27e-3)" "unprognostic (1.79e-1)" "unprognostic (1.63e-1)" "unprognostic (1.94e-2)" "unprognostic (4.27e-1)" "unprognostic (1.62e-2)" "unprognostic (1.52e-1)" 2.4 17.4 0.7 17.2 0.2 1.2 23.8 2.3 0.8 127.2 0.7 61.8 75.8 2.2 19.9 491.6 10.5 77.1 0.6 0.3 2.0 99.5 484.7 59.6 7.3 0.6 17.3 1.6 16.6 5.4 2.0 32.6 0.8 56.3 33.3 0.7 85.8 25.9 1.6 447.4 53.6 2.2 0.2 20.1 87.3 3.3 2.5 5.1 18.3 0.0 43.2 104.8 242.1 0.1 252.6 137.6 42.7 108.1 11.6 1.6 134.9 68.7 65.4 62.7 52.8 29.5 148.9 0.3 24.8 48.8 34.8 241.4 19.0 482.2 41.8 1.3 12.5 0.0 12.2 150.2 10.3 11.0 1.0 6.4 436.6 56.5 132.9 87.2 6.9 0.0 6.4 94.7 34.0 149.6 0.6 2.6 38.7 189.6 263.1 5.3 15.7 189.9 80.5 370.0 12.4 99.7 51.9 342.4 15.2 17.1 34.5 2.8 10.7 246.9 78.6 9.2 470.0 467.4 1069.8 1.0 74.5 0.6 28.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.2 2.3 0.8 0.3 2.0 0.6 17.3 0.8 0.2 2.5 0.1 0.4 93.0 99.0 0.0 33.0 113.9 189.1 162.8 81.4 0.6 29.9 26.7 0.9 267.4 161.8 42.3 0.0 3.8 0.7 147.2 31.3 61.3 0.1 16.6 5.0 3.5 10.8 13.5 0.3 21.8 46.3 5.0 55.0 22.9 6.3 7.5 7.5 603.1 2.3 21.9 0.2 73.1 50.8 10.6 11.9 0.3 0.6 2.5 21.4 0.0 0.6 0.3 0.0 1.0 0.0 111.4 78.0 1.2 165.1 78.0 106.5 88.5 43.4 0.4 0.0 0.1 15.0 1.0 14.0 246.6 229.0 250.8 4.0 0.1 85.1 492.8 SENP1 ENSG00000079387 "SUMO specific peptidase 1" Q9P0U3 12 48042897-48106079 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 32.5;testis: 61.8" "Cell type enhanced" "Detected in many" "Spermatocytes: 86.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011765, HPA046491" Supported "Nucleoplasm,Focal adhesion sites" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 32: U-937 - Innate immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "Focal adhesion sites" "HPA011765: AB_1079907, HPA046491: AB_2679672" "unprognostic (2.66e-2)" "unprognostic (6.51e-2)" "unprognostic (3.14e-1)" "unprognostic (5.69e-2)" "unprognostic (2.83e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (7.72e-5)" "unprognostic (6.48e-2)" "unprognostic (2.44e-3)" "unprognostic (8.20e-3)" "unprognostic (2.57e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (8.37e-4)" "unprognostic (7.61e-2)" "unprognostic (3.02e-1)" "unprognostic (1.01e-1)" "unprognostic (1.28e-1)" 5.0 3.6 3.1 9.1 3.9 14.4 5.6 8.3 3.7 6.2 1.9 4.9 4.8 7.5 5.1 7.5 4.7 5.5 3.8 2.7 5.0 3.8 3.8 4.6 12.0 3.0 3.6 5.5 4.4 6.3 3.3 6.5 3.7 4.8 6.8 6.5 32.5 4.7 3.7 6.8 4.7 7.0 2.2 6.3 4.8 61.8 3.4 12.2 5.8 4.3 12.9 6.1 3.9 5.0 13.8 17.7 22.4 16.3 6.4 9.8 15.7 14.9 17.1 25.8 20.7 22.2 22.3 38.0 12.8 13.9 9.9 13.0 28.0 13.0 25.7 34.6 11.4 33.9 17.9 10.9 10.1 32.2 22.4 7.4 10.4 22.7 20.1 11.4 13.7 25.2 30.2 15.9 13.4 12.0 40.1 11.2 20.0 9.5 12.8 36.6 23.6 19.1 7.2 17.3 22.8 15.4 21.9 13.2 8.8 12.7 20.6 14.4 12.2 21.1 18.4 12.5 16.4 18.4 32.5 36.7 13.3 71.4 10.0 0.8 0.8 2.9 1.6 1.1 2.1 1.0 1.6 1.6 1.4 1.8 1.4 1.5 1.6 1.6 0.8 1.5 1.9 1.0 3.1 3.9 8.3 3.7 2.7 5.0 3.0 3.6 3.7 2.2 3.4 5.0 11.2 9.6 8.9 18.9 14.3 3.7 4.7 4.7 6.8 7.9 6.7 4.7 3.2 4.3 7.6 3.7 4.2 4.0 9.1 3.6 3.9 3.9 16.7 5.6 11.6 9.1 3.5 11.1 14.0 6.5 3.4 7.3 7.7 5.0 6.3 9.8 6.8 6.6 4.5 15.2 15.9 4.2 8.2 9.5 4.2 6.0 6.2 7.7 1.8 15.0 7.2 5.2 5.2 17.6 17.8 5.8 1.9 6.8 13.5 4.4 2.8 3.7 4.6 8.7 0.0 9.8 8.3 86.5 31.0 8.5 6.1 2.7 12.2 7.4 4.2 3.8 SHROOM4 KIAA1202 ENSG00000158352 "Shroom family member 4" Q9ULL8 X 50591642-50814302 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Developmental protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.7" "Group enriched" "Detected in many" 5 "Oligodendrocyte precursor cells: 126.7;Oligodendrocytes: 463.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 7.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 6.7;HUVEC TERT2: 26.7;RH-30: 5.0;RPTEC TERT1: 5.5;TIME: 10.0;WM-115: 5.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA010089, HPA010565" Uncertain Approved "Nucleoplasm,Vesicles,Focal adhesion sites" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Focal adhesion sites" "Nucleoplasm, Vesicles" "HPA010089: , HPA010565: AB_1079961" "unprognostic (2.55e-2)" "unprognostic (1.43e-1)" "unprognostic (5.56e-2)" "prognostic unfavorable (8.37e-4)" "unprognostic (1.34e-1)" "unprognostic (1.60e-2)" "unprognostic (4.30e-3)" "unprognostic (4.55e-2)" "unprognostic (2.13e-1)" "unprognostic (2.93e-1)" "unprognostic (1.52e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (4.66e-4)" "unprognostic (7.30e-2)" "unprognostic (2.83e-1)" "unprognostic (1.74e-2)" "unprognostic (2.75e-1)" 8.1 1.8 9.8 1.9 20.0 1.2 5.4 17.1 12.4 3.3 0.9 1.8 1.1 3.6 1.6 2.7 2.2 3.0 7.8 8.9 12.6 5.3 0.9 13.3 0.9 23.8 17.6 1.3 0.9 1.9 2.0 9.0 21.8 2.2 1.4 1.3 2.0 1.8 3.6 1.7 1.5 4.1 13.8 1.0 1.3 0.6 17.3 0.6 3.3 5.0 1.0 3.5 2.3 30.7 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.1 0.2 0.0 6.7 0.9 0.0 0.6 4.3 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.4 0.0 0.0 0.5 0.0 26.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 5.0 0.0 5.5 2.5 0.1 0.0 0.0 0.8 1.5 3.6 0.1 0.1 10.0 0.0 0.0 0.0 0.7 0.5 0.0 0.0 1.3 0.2 5.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 20.0 17.1 12.4 8.9 12.6 23.8 17.6 21.8 13.8 17.3 30.7 45.0 25.6 18.6 3.3 0.0 3.6 2.0 1.9 2.2 0.3 1.0 1.5 4.2 0.0 2.0 5.5 0.0 0.6 0.2 1.1 3.9 0.7 0.1 2.8 5.4 46.5 3.0 0.0 1.1 0.2 3.0 3.0 0.0 2.9 3.8 2.3 30.7 0.9 0.5 0.0 1.1 2.8 0.0 2.4 2.7 0.6 1.2 0.6 0.0 51.5 0.0 3.6 0.0 126.7 463.4 2.3 1.0 1.2 0.0 1.2 0.3 3.5 2.5 0.6 0.0 2.5 2.6 0.0 1.0 2.0 3.1 0.3 0.6 3.0 3.2 1.6 SIKE1 "FLJ21168, SIKE" ENSG00000052723 "Suppressor of IKBKE 1" Q9BRV8 1 114769479-114780685 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024177, HPA025726" Supported Approved "Vesicles,Focal adhesion sites" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 43: THP-1 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" "Focal adhesion sites" Vesicles "HPA024177: AB_1848798, HPA025726: AB_1848800" "unprognostic (1.38e-1)" "unprognostic (1.90e-1)" "unprognostic (3.53e-2)" "unprognostic (4.52e-3)" "unprognostic (4.10e-1)" "unprognostic (6.04e-2)" "unprognostic (3.37e-3)" "unprognostic (2.11e-1)" "unprognostic (1.72e-2)" "unprognostic (2.52e-2)" "unprognostic (1.94e-2)" "unprognostic (7.91e-2)" "unprognostic (2.38e-2)" "unprognostic (3.86e-2)" "unprognostic (9.06e-2)" "unprognostic (2.95e-3)" "unprognostic (1.05e-1)" 8.8 6.9 5.9 9.7 6.0 9.8 9.6 8.5 6.7 9.1 5.7 8.6 9.8 9.4 7.6 7.7 6.0 6.9 7.3 4.9 7.7 10.8 12.2 6.8 12.1 7.0 6.8 8.6 6.8 9.7 4.9 9.6 7.0 7.6 9.4 8.0 7.3 7.5 6.7 13.4 8.5 9.2 6.4 9.5 8.4 5.6 8.2 13.6 10.1 7.4 12.0 7.2 5.6 7.1 16.3 4.4 22.9 21.2 27.6 21.4 22.0 13.9 12.4 18.9 25.3 12.2 9.1 30.6 12.5 11.8 8.0 15.7 24.3 16.7 27.0 19.4 13.3 16.4 13.9 15.6 26.3 18.8 12.9 21.0 19.6 14.1 22.4 13.6 17.5 26.2 25.2 17.7 15.7 62.7 37.1 19.9 52.1 10.5 12.3 21.2 43.7 15.3 16.0 13.5 15.7 18.5 20.0 23.2 25.5 20.8 12.6 72.0 13.9 15.6 19.0 26.8 19.0 16.4 14.1 29.1 23.7 31.1 34.0 6.0 1.7 2.0 2.2 2.3 2.8 2.0 2.2 2.2 2.2 2.1 2.6 2.8 1.2 2.6 2.4 2.7 1.7 1.4 5.9 6.0 8.5 6.7 4.9 7.7 7.0 6.8 7.0 6.4 8.2 7.1 29.2 25.6 14.8 13.1 32.7 31.9 26.7 40.0 30.1 10.7 22.7 23.2 41.0 20.0 30.2 31.3 10.4 29.7 43.9 30.3 50.9 27.1 34.8 20.1 34.9 26.3 18.6 29.9 16.2 25.7 33.6 27.9 18.8 26.8 19.7 77.1 27.1 40.0 27.7 8.4 19.7 21.4 48.8 19.7 26.6 58.1 28.3 24.8 23.2 4.7 25.4 15.8 32.0 10.1 16.6 31.1 18.3 19.9 37.7 30.5 25.7 62.8 21.3 16.1 19.7 26.5 28.8 35.5 39.6 33.0 36.4 36.0 37.4 48.3 21.2 23.6 SLC16A8 "MCT3, REMP" ENSG00000100156 "Solute carrier family 16 member 8" O95907 22 38078134-38084093 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 9.1" "Cell type enhanced" "Detected in some" "Leydig cells: 4.4;Melanocytes: 5.4;Oligodendrocytes: 4.0;Spermatogonia: 7.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.0;SiHa: 2.1;T-47d: 1.3;U-2 OS: 1.2;U-266/70: 4.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA075017 Approved Approved "Intermediate filaments,Focal adhesion sites" No NA "Cluster 65: Brain - Ion transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Focal adhesion sites" "Intermediate filaments" "HPA075017: AB_2732276" "unprognostic (1.22e-2)" "unprognostic (2.25e-2)" "unprognostic (5.07e-6)" "unprognostic (2.99e-2)" "unprognostic (1.37e-1)" "unprognostic (1.84e-2)" "unprognostic (2.99e-2)" "unprognostic (1.74e-1)" "unprognostic (1.24e-1)" "unprognostic (1.76e-1)" "unprognostic (1.63e-2)" "unprognostic (1.32e-2)" "unprognostic (2.34e-4)" "unprognostic (7.69e-2)" "unprognostic (1.15e-1)" "unprognostic (4.06e-1)" "unprognostic (9.71e-5)" 0.5 0.3 1.1 0.0 3.3 0.2 0.6 0.2 6.0 0.7 0.0 0.3 0.1 0.4 0.0 0.3 0.9 0.1 0.6 0.8 1.1 0.4 0.2 0.3 0.0 4.0 1.4 0.3 0.4 0.0 1.6 0.0 3.6 1.7 0.0 0.1 1.2 0.0 0.5 0.7 0.2 0.0 0.3 0.3 0.4 0.8 2.8 0.0 0.7 0.0 0.0 0.4 0.7 9.1 0.3 0.0 0.1 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.1 0.7 0.1 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.6 0.4 0.1 2.1 0.0 0.2 0.1 1.3 0.0 0.0 0.0 1.2 0.0 0.0 4.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 3.3 0.2 6.0 0.8 1.1 4.0 1.4 3.6 0.3 2.8 9.1 0.6 0.0 0.0 0.7 0.0 1.3 0.5 0.6 0.6 0.1 0.6 0.8 0.7 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.1 1.3 0.1 0.9 0.2 0.0 0.0 0.4 0.0 0.0 2.2 0.0 0.4 0.0 1.7 0.7 0.1 1.0 0.0 0.4 0.2 0.0 0.8 1.4 2.5 4.4 0.7 5.4 0.0 0.0 1.4 0.0 0.5 4.0 0.3 0.0 2.2 0.0 0.3 0.0 0.0 0.0 0.7 0.0 1.5 2.4 2.1 7.7 0.5 0.9 0.0 0.3 0.6 0.1 0.7 SLC4A7 "NBC3, SBC2, SLC4A6" ENSG00000033867 "Solute carrier family 4 member 7" Q9Y6M7 3 27372721-27484420 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 57.6;retina: 72.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 733.9;Rod photoreceptor cells: 704.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "hTERT-HME1: 78.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022494, HPA035857" Enhanced Supported "Plasma membrane,Focal adhesion sites,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane" "Focal adhesion sites, Cytosol" "CAB022494: , HPA035857: AB_10795135" "unprognostic (2.94e-2)" "unprognostic (6.34e-2)" "unprognostic (1.80e-3)" "unprognostic (1.91e-1)" "unprognostic (8.48e-3)" "unprognostic (2.68e-1)" "unprognostic (6.79e-4)" "unprognostic (4.13e-2)" "unprognostic (1.40e-1)" "unprognostic (1.64e-1)" "unprognostic (1.83e-1)" "unprognostic (8.58e-3)" "prognostic unfavorable (7.91e-6)" "unprognostic (1.09e-2)" "unprognostic (6.68e-2)" "unprognostic (1.93e-1)" "unprognostic (7.26e-2)" 8.6 5.1 3.2 9.0 5.2 4.0 18.7 3.4 16.9 10.5 1.6 16.2 57.6 6.4 8.2 8.6 6.0 13.7 7.8 19.3 2.5 12.7 3.9 8.3 11.2 0.5 3.2 6.8 3.4 1.7 3.4 5.8 0.6 7.9 7.4 72.9 5.8 8.7 5.0 4.6 17.4 6.6 1.8 7.0 6.0 7.1 4.4 5.8 4.9 27.2 10.3 12.1 8.8 2.6 13.0 23.8 21.0 9.8 9.6 17.2 15.0 43.3 20.0 16.3 12.6 6.5 6.6 29.4 3.6 16.8 15.7 5.5 20.2 21.1 25.7 25.1 6.6 13.5 15.4 7.1 16.5 30.9 11.3 13.7 9.0 24.8 78.9 34.2 27.1 19.0 9.1 10.1 33.8 4.7 31.1 7.2 13.8 1.6 23.4 21.0 16.7 5.9 38.1 9.2 5.3 13.1 19.7 14.4 6.9 17.9 32.9 11.8 19.0 38.2 10.6 26.7 33.7 3.8 4.3 16.6 33.3 21.4 17.8 0.0 0.2 0.0 1.0 0.2 0.7 0.4 1.3 1.4 0.5 0.5 0.5 0.9 0.0 1.0 0.3 0.7 1.2 0.3 3.2 5.2 3.4 16.9 19.3 2.5 0.5 3.2 0.6 1.8 4.4 2.6 30.0 0.0 11.2 10.7 37.5 29.3 39.5 23.4 11.4 130.2 72.4 30.4 23.1 21.5 22.8 62.5 733.9 5.8 51.8 5.5 9.8 15.5 10.2 73.6 40.7 53.6 38.2 7.2 46.2 7.1 29.3 52.2 15.8 124.1 23.5 24.6 17.5 6.2 17.0 6.7 88.7 58.5 36.7 48.4 61.6 7.6 9.0 46.5 35.6 185.5 26.7 45.7 20.6 60.8 20.9 19.1 23.4 9.8 27.8 93.1 142.5 10.2 9.6 704.2 39.5 56.4 43.7 40.0 21.7 21.7 30.7 8.1 56.1 19.0 26.7 35.2 SMIM11A "C21orf51, FAM165B, SMIM11" ENSG00000205670 "Small integral membrane protein 11A" P58511 21 34375480-34416961 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in some" 4 "Gastric mucus-secreting cells: 12.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA051321 Uncertain Approved "Focal adhesion sites" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Focal adhesion sites" "HPA051321: AB_2681440" "unprognostic (2.62e-2)" "unprognostic (4.28e-2)" "unprognostic (1.27e-1)" "unprognostic (5.86e-3)" "unprognostic (1.90e-1)" "unprognostic (1.66e-1)" "unprognostic (3.04e-1)" "unprognostic (4.48e-2)" "unprognostic (1.13e-1)" "unprognostic (2.74e-1)" "unprognostic (8.84e-2)" "unprognostic (4.83e-3)" 10.2 8.9 19.8 12.1 20.6 13.0 6.6 20.4 32.6 10.3 24.4 7.5 14.9 9.7 14.5 9.3 9.2 13.6 21.9 19.9 20.8 17.8 14.5 8.1 15.8 21.4 20.2 16.7 11.6 11.2 3.6 5.8 21.0 10.5 6.5 13.2 14.3 4.8 35.9 6.3 11.7 11.3 21.5 11.4 30.5 6.3 20.0 6.7 20.6 11.4 6.5 12.7 2.7 23.5 24.7 9.8 11.1 33.0 21.0 6.5 22.6 9.0 4.3 12.5 25.1 12.7 22.7 57.4 11.8 11.6 16.5 15.1 18.8 0.7 11.9 32.0 8.9 33.1 23.0 12.7 19.0 55.6 7.8 15.5 10.8 13.6 31.1 24.5 14.2 12.1 51.4 65.7 13.2 13.2 2.2 43.5 52.2 15.5 34.5 31.1 25.2 82.5 10.8 6.2 28.3 20.4 14.8 18.5 39.0 20.3 18.2 25.1 18.1 18.1 13.4 8.0 16.9 25.1 28.3 54.0 33.6 70.0 33.0 5.6 6.3 14.9 6.9 10.1 11.4 6.5 11.7 16.8 8.5 17.1 8.5 11.4 3.6 14.4 9.2 7.6 14.1 9.5 19.8 20.6 20.4 32.6 19.9 20.8 21.4 20.2 21.0 21.5 20.0 23.5 0.1 3.2 2.6 0.0 0.4 0.0 0.4 0.0 0.0 0.8 0.8 0.3 0.0 0.0 0.6 0.0 0.0 0.3 0.1 0.3 1.9 1.5 0.4 0.1 0.4 0.7 1.2 0.0 0.0 0.7 0.3 0.7 12.8 0.2 0.0 0.2 0.7 1.4 0.7 0.0 0.0 0.8 0.0 0.6 0.0 0.3 0.0 0.6 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.9 0.3 0.4 0.6 0.3 1.4 2.2 2.2 0.4 0.0 0.3 0.3 0.6 0.5 0.0 0.0 0.1 0.4 0.1 0.6 0.1 SMIM11B ENSG00000273590 "Small integral membrane protein 11B" Q8TCY0 21 7744962-7777853 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 16.0;Alveolar cells type 2: 5.6;Club cells: 4.3;Distal tubular cells: 3.9;granulocytes: 5.1;Respiratory ciliated cells: 10.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA051321 Uncertain Approved "Focal adhesion sites" NA NA "Cluster 37: B-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 11: Alveolar cells - Smell perception" "Focal adhesion sites" "HPA051321: AB_2681440" "unprognostic (1.99e-1)" "unprognostic (1.78e-1)" "unprognostic (1.35e-1)" 14.6 17.0 22.5 1.1 22.6 0.5 15.6 21.7 24.1 17.6 21.7 23.3 2.1 16.8 15.0 9.3 19.2 3.1 30.7 22.3 22.5 24.3 20.6 11.3 4.8 24.7 23.1 20.6 18.6 9.1 21.3 4.2 22.2 17.4 5.7 10.0 15.4 11.2 37.3 9.8 13.9 3.4 19.7 14.0 58.2 6.5 22.4 12.2 19.5 16.3 8.5 18.4 14.3 23.4 23.6 9.6 7.7 17.3 19.0 37.9 0.2 8.8 30.0 11.2 0.8 1.0 1.4 1.1 7.0 14.3 23.8 1.1 17.0 27.7 10.0 34.3 45.9 19.2 1.2 13.8 19.5 3.1 25.9 18.8 26.6 0.4 1.4 7.9 14.5 29.3 31.2 3.6 10.6 11.9 26.6 2.1 0.6 36.3 0.6 1.1 0.4 1.2 34.7 6.2 16.2 1.9 21.6 15.3 17.7 0.6 28.2 0.8 3.1 10.9 4.5 9.2 9.8 19.2 20.6 1.5 0.1 9.9 1.5 1.5 11.0 4.6 11.6 5.8 11.3 19.6 9.1 6.0 11.4 12.2 16.1 9.7 0.9 1.4 5.0 8.4 14.7 6.4 22.5 22.6 21.7 24.1 22.3 22.5 24.7 23.1 22.2 19.7 22.4 23.4 0.1 16.0 5.6 0.0 0.2 0.0 0.6 0.0 0.0 0.8 0.8 0.3 0.0 1.5 4.3 0.0 0.0 0.3 0.3 0.3 3.9 0.5 0.2 0.2 0.1 0.4 0.0 2.7 0.0 0.4 0.3 2.1 0.0 0.1 5.1 0.1 0.4 0.6 0.4 0.0 0.0 0.3 0.0 0.8 0.0 0.3 0.3 0.3 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.3 0.1 0.4 0.1 0.3 0.3 1.9 10.9 0.3 0.0 0.9 0.1 0.3 0.4 0.0 0.0 0.3 0.6 0.1 0.5 0.3 SNX32 "FLJ30934, SNX6B" ENSG00000172803 "Sorting nexin 32" Q86XE0 11 65833834-65856896 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 12 "brain: 37.8;choroid plexus: 15.0" "Cell type enhanced" "Detected in some" "Astrocytes: 25.5;Early spermatids: 11.3;Excitatory neurons: 48.4;Inhibitory neurons: 34.2;Late spermatids: 12.3;Oligodendrocyte precursor cells: 12.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HHSteC: 4.5;HSkMC: 5.8;REH: 1.9;SH-SY5Y: 2.3;U-266/70: 7.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041775 Uncertain Uncertain "Cell Junctions,Focal adhesion sites" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Cell Junctions, Focal adhesion sites" "HPA041775: AB_10797268" "unprognostic (6.74e-4)" "unprognostic (1.06e-1)" "unprognostic (1.67e-2)" "unprognostic (4.50e-5)" "unprognostic (1.00e-1)" "unprognostic (9.28e-2)" "unprognostic (7.30e-2)" "unprognostic (9.17e-3)" "unprognostic (2.70e-1)" "unprognostic (2.87e-1)" "unprognostic (5.08e-2)" "unprognostic (1.52e-1)" "unprognostic (3.64e-4)" "unprognostic (2.14e-1)" "unprognostic (1.14e-1)" "unprognostic (9.80e-2)" "unprognostic (5.36e-2)" 0.3 0.1 22.8 0.1 24.0 0.3 0.3 17.1 37.8 0.6 15.0 1.0 1.0 0.7 0.2 0.1 0.7 0.8 0.2 23.7 17.8 0.2 0.0 0.1 0.1 18.1 18.2 0.7 0.1 0.2 0.4 0.0 18.3 0.2 0.4 1.1 0.0 0.1 0.0 0.4 0.5 0.5 16.9 0.2 0.2 2.1 18.7 0.4 0.1 0.2 0.2 0.4 0.2 23.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.5 0.0 0.5 5.8 0.1 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.3 0.0 0.4 0.2 0.1 0.0 0.0 1.9 0.0 1.8 0.0 0.0 0.0 2.3 0.0 0.0 1.2 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 7.0 1.2 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.3 0.1 0.7 0.0 0.3 0.2 0.3 0.2 0.3 0.1 0.0 0.0 0.0 0.1 0.3 0.0 22.8 24.0 17.1 37.8 23.7 17.8 18.1 18.2 18.3 16.9 18.7 23.1 0.3 0.0 0.6 25.5 0.6 0.4 0.3 0.0 1.2 2.4 0.7 1.0 0.8 0.0 0.6 0.0 0.0 0.1 0.1 0.6 0.0 0.1 11.3 0.3 3.6 0.6 0.0 0.8 48.4 0.0 0.4 0.9 1.1 0.5 3.8 2.8 0.4 0.0 0.3 0.0 34.2 0.8 0.0 0.3 0.3 12.3 0.3 0.2 1.8 3.7 0.0 0.9 1.0 12.1 10.2 0.2 0.5 1.2 0.5 0.2 3.9 0.4 0.7 0.6 0.0 1.0 0.8 6.1 1.7 0.5 0.4 0.0 0.7 1.3 1.7 0.1 SORBS1 "CAP, FLJ12406, KIAA1296, ponsin, SH3D5, sh3p12" ENSG00000095637 "Sorbin and SH3 domain containing 1" Q9BX66 10 95311771-95561414 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 800.2;Cardiomyocytes: 612.3;Excitatory neurons: 401.1;Inhibitory neurons: 295.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "basophil: 6.1" "Lineage enriched" "Detected in single" 10 "granulocytes: 6.1" "Cell line enhanced" "Detected in many" "CACO-2: 28.0;Hep G2: 19.5;HMC-1: 48.3;SK-MEL-30: 45.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027559, CAB032850, HPA043084" Enhanced Supported "Plasma membrane,Focal adhesion sites,Centrosome" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Focal adhesion sites" "Plasma membrane, Centrosome" "CAB032850: AB_2286335, HPA027559: AB_10600812, HPA043084: AB_2678307" "prognostic favorable (2.84e-4)" "unprognostic (3.53e-1)" "unprognostic (1.89e-1)" "unprognostic (7.85e-2)" "unprognostic (3.43e-1)" "unprognostic (1.41e-1)" "unprognostic (2.98e-2)" "unprognostic (5.30e-2)" "unprognostic (1.95e-2)" "unprognostic (1.65e-2)" "unprognostic (3.17e-2)" "unprognostic (1.27e-1)" "unprognostic (3.40e-2)" "unprognostic (3.13e-2)" "unprognostic (1.80e-1)" "unprognostic (2.55e-2)" "unprognostic (5.01e-3)" 370.8 21.6 128.5 53.3 153.3 4.7 78.3 101.7 144.1 46.0 42.6 312.8 25.6 169.4 32.1 155.5 99.2 81.3 351.6 127.0 165.4 17.6 49.3 34.4 3.1 164.0 161.5 19.0 22.0 26.4 11.5 30.3 126.7 140.6 67.0 39.0 24.5 217.4 190.5 24.5 62.7 151.0 138.9 8.1 143.1 14.4 127.0 3.7 14.8 155.9 1.5 235.3 47.1 139.9 1.6 1.2 12.4 3.1 4.2 0.2 2.4 0.4 0.1 0.4 0.1 28.0 10.9 0.0 2.2 0.2 4.2 0.6 2.4 0.6 0.4 3.2 4.5 7.2 0.4 19.5 1.5 0.0 48.3 0.9 0.4 0.5 0.3 0.2 4.9 1.9 11.7 2.3 1.3 0.8 0.1 0.8 5.7 6.2 2.6 1.0 4.0 0.4 15.1 18.3 4.9 3.7 1.8 0.6 45.2 8.9 2.1 0.4 0.3 0.1 4.0 0.1 2.4 1.8 0.5 0.2 4.8 0.5 11.7 6.1 0.1 1.2 0.4 0.6 0.5 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.4 0.1 0.0 0.3 0.1 128.5 153.3 101.7 144.1 127.0 165.4 164.0 161.5 126.7 138.9 127.0 139.9 42.2 22.4 20.9 800.2 0.8 11.6 8.7 0.0 5.2 7.5 6.5 19.3 612.3 12.8 1.3 1.8 2.1 20.2 1.0 4.0 3.9 7.2 70.4 1.4 15.8 25.7 6.0 16.0 401.1 3.1 2.4 21.4 8.6 1.6 16.4 8.2 30.4 50.5 3.1 6.7 295.1 10.9 0.0 3.8 12.0 48.6 7.5 1.1 14.2 163.9 0.7 22.1 1.0 155.3 22.6 2.3 2.8 76.8 1.1 4.7 1.2 6.1 0.1 5.5 0.0 11.8 51.6 3.4 3.7 1.9 12.5 29.6 1.6 0.1 5.1 5.9 SORBS3 "SCAM-1, SH3D4, vinexin" ENSG00000120896 "Sorbin and SH3 domain containing 3" O60504 8 22544986-22575788 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 169.4;Late spermatids: 505.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015849 Approved Uncertain "Focal adhesion sites,Cytosol" NA NA 7700 "Cluster 16: MAIT-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "Focal adhesion sites" "HPA015849: AB_1857365" "unprognostic (6.15e-3)" "unprognostic (2.09e-2)" "unprognostic (2.34e-1)" "unprognostic (3.90e-3)" "unprognostic (1.72e-1)" "unprognostic (9.30e-2)" "unprognostic (2.51e-2)" "unprognostic (2.44e-2)" "unprognostic (5.83e-3)" "unprognostic (1.70e-1)" "prognostic favorable (4.88e-4)" "unprognostic (4.21e-2)" "unprognostic (3.08e-3)" "unprognostic (7.41e-2)" "unprognostic (1.58e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (1.53e-5)" 173.3 65.3 59.3 26.2 59.7 5.1 129.0 67.6 72.6 156.9 49.9 105.2 29.9 124.0 23.6 65.5 118.8 38.7 105.8 53.0 55.3 84.8 121.2 111.9 21.1 85.0 60.6 125.6 49.3 35.7 73.3 66.6 65.6 127.2 34.9 11.4 88.7 48.5 64.7 106.8 71.2 53.7 61.7 80.0 63.7 128.2 65.7 7.6 93.8 37.3 13.4 103.5 133.9 57.6 83.0 101.8 54.6 61.9 86.4 114.4 55.7 83.0 127.8 95.0 58.8 103.6 36.2 0.7 55.3 130.1 38.3 69.7 82.5 75.7 48.9 58.1 36.2 6.9 58.3 48.4 98.2 0.8 0.5 72.6 55.6 33.3 48.4 105.2 74.6 42.7 18.4 2.6 68.4 32.8 7.1 2.4 19.3 14.1 42.5 79.0 36.8 7.7 43.7 15.8 3.1 48.9 40.4 9.8 52.7 56.8 16.7 29.2 116.9 83.8 59.8 61.9 59.3 1.7 2.5 11.5 49.0 19.4 58.3 0.0 2.5 0.6 11.4 4.7 23.4 0.8 12.6 13.4 8.1 1.3 12.7 7.6 0.5 5.8 1.1 2.7 0.6 5.2 59.3 59.7 67.6 72.6 53.0 55.3 85.0 60.6 65.6 61.7 65.7 57.6 89.6 19.2 7.2 27.1 5.8 29.2 24.6 23.3 39.9 2.7 29.0 27.8 12.2 31.5 18.3 12.9 0.0 24.1 4.7 53.5 9.8 21.3 169.4 10.9 39.5 51.9 14.6 2.1 3.8 19.2 30.5 48.8 8.6 20.5 17.2 19.3 79.9 49.5 35.3 5.0 4.5 35.2 8.2 39.0 31.5 505.8 61.2 23.8 24.9 13.1 5.7 21.9 3.1 19.6 7.6 26.2 53.2 58.6 3.7 38.8 65.1 26.0 10.7 3.5 59.2 23.1 84.1 7.0 8.0 25.3 21.3 20.5 19.7 7.1 31.3 23.7 TADA1 "ADA1, hADA1, HFI1, STAF42, TADA1L" ENSG00000152382 "Transcriptional adaptor 1" Q96BN2 1 166856510-166876264 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028651 Approved Supported "Nucleoplasm,Focal adhesion sites,Cytosol" No No "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 5: NTERA-2 - Transcription" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Focal adhesion sites, Cytosol" "HPA028651: AB_10602476" "unprognostic (9.53e-3)" "unprognostic (2.31e-1)" "unprognostic (1.05e-2)" "unprognostic (4.10e-2)" "unprognostic (1.55e-1)" "unprognostic (7.09e-2)" "unprognostic (5.99e-3)" "unprognostic (7.31e-2)" "unprognostic (3.35e-2)" "unprognostic (1.22e-2)" "unprognostic (1.40e-1)" "unprognostic (1.98e-2)" "unprognostic (3.64e-2)" "unprognostic (2.73e-2)" "unprognostic (6.35e-2)" "unprognostic (1.07e-1)" "unprognostic (1.26e-2)" 5.1 8.9 9.6 6.1 10.3 19.4 9.2 9.9 12.4 7.7 8.1 8.4 7.7 9.3 7.6 8.3 8.6 5.3 8.6 10.1 9.3 11.6 26.7 6.2 10.4 7.8 8.3 11.0 6.4 10.9 6.2 8.2 8.8 7.9 9.1 17.0 8.1 7.1 9.8 8.0 8.4 7.6 9.2 6.9 7.5 10.8 9.3 13.2 7.5 10.6 10.1 6.6 5.8 11.2 15.7 14.9 27.4 16.3 8.1 10.4 16.2 8.1 9.9 13.2 11.4 13.7 12.5 29.9 15.4 9.6 10.7 11.8 22.3 14.3 10.6 18.9 21.3 9.9 11.9 22.5 12.0 28.3 17.4 7.9 16.3 8.0 19.9 9.6 11.0 22.2 35.9 17.6 10.5 10.9 34.9 22.5 41.6 25.2 16.5 29.1 12.0 37.9 18.0 20.9 17.5 30.6 14.6 18.7 17.5 25.0 25.3 29.3 8.3 10.8 12.4 11.9 17.3 24.9 36.3 56.3 7.5 12.6 10.4 2.9 12.7 13.8 20.7 12.9 22.9 20.2 22.2 23.6 20.7 20.8 27.9 22.3 2.1 27.5 10.4 13.3 23.4 24.7 9.6 10.3 9.9 12.4 10.1 9.3 7.8 8.3 8.8 9.2 9.3 11.2 2.7 9.6 2.7 7.8 8.4 6.1 4.7 3.9 6.2 7.6 4.9 4.6 10.3 2.8 4.1 3.7 8.4 6.1 4.9 4.4 5.9 3.9 4.0 4.8 4.6 4.3 7.2 13.7 9.6 4.0 7.7 4.8 6.6 4.4 5.1 6.1 3.3 20.3 4.2 1.7 10.5 6.1 0.0 5.3 5.1 1.7 4.4 2.6 1.8 3.7 6.9 6.8 4.1 7.5 17.7 3.8 1.7 3.0 7.5 6.2 5.3 7.0 4.3 6.0 0.0 6.1 4.1 5.2 12.9 7.6 5.1 7.3 7.3 1.9 5.9 4.2 TAS2R42 "hT2R55, T2R24, T2R55, TAS2R55" ENSG00000186136 "Taste 2 receptor member 42" Q7RTR8 12 11185993-11186937 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA036149 Uncertain Approved "Nucleoplasm,Actin filaments,Focal adhesion sites" NA NA "Nucleoplasm, Actin filaments" "Focal adhesion sites" "HPA036149: AB_10672080" "unprognostic (2.45e-2)" "unprognostic (4.17e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TATDN3 ENSG00000203705 "TatD DNase domain containing 3" Q17R31 1 212791828-212816830 "Predicted intracellular proteins" "Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032092 Approved Approved "Nucleoplasm,Golgi apparatus,Focal adhesion sites" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "Golgi apparatus, Focal adhesion sites" "HPA032092: AB_10671086" "unprognostic (9.81e-2)" "unprognostic (1.57e-2)" "unprognostic (1.20e-1)" "unprognostic (3.17e-1)" "unprognostic (1.46e-1)" "unprognostic (1.74e-1)" "unprognostic (9.38e-2)" "unprognostic (4.16e-2)" "unprognostic (3.80e-1)" "unprognostic (3.88e-2)" "unprognostic (3.34e-3)" "unprognostic (5.02e-3)" "prognostic favorable (1.59e-4)" "unprognostic (1.93e-1)" "unprognostic (2.44e-1)" "unprognostic (3.13e-3)" "unprognostic (2.96e-3)" 13.0 11.3 10.1 10.4 12.4 12.2 10.0 10.1 12.7 6.5 9.3 8.3 6.1 7.1 13.3 7.3 7.7 7.4 19.3 10.6 12.4 16.6 10.3 8.0 12.2 12.2 10.5 8.6 9.4 18.2 8.2 7.3 12.4 6.9 7.7 17.7 8.5 6.9 29.9 6.3 7.2 7.7 10.5 11.1 11.1 10.0 10.4 11.2 11.7 24.1 10.3 8.2 5.5 15.8 12.2 11.9 10.3 15.1 16.7 26.0 23.5 12.9 14.3 10.8 13.1 3.1 17.2 27.4 12.3 12.4 6.0 7.6 13.0 18.2 11.5 17.1 17.0 13.4 10.3 6.3 19.0 33.3 16.3 20.6 12.8 14.3 37.3 11.2 16.1 37.7 28.2 21.7 11.7 5.9 28.4 10.9 13.9 14.9 7.6 16.0 19.3 49.4 11.3 6.3 21.6 18.5 14.5 25.1 30.6 19.2 26.6 19.6 10.1 7.9 10.3 16.4 13.0 19.4 32.9 44.9 20.6 26.8 12.0 26.1 37.2 60.2 12.7 59.3 11.5 39.7 15.8 15.4 45.6 31.0 12.5 14.9 42.8 13.8 64.4 74.6 16.1 22.9 10.1 12.4 10.1 12.7 10.6 12.4 12.2 10.5 12.4 10.5 10.4 15.8 9.1 6.4 16.2 17.3 18.5 4.5 8.1 14.2 3.4 16.1 8.5 8.3 36.6 8.6 8.0 3.7 18.8 14.3 39.7 3.4 41.1 18.1 12.2 10.8 7.6 8.9 10.2 6.5 35.1 16.5 17.5 10.0 6.1 7.8 7.0 10.8 5.3 7.0 18.8 15.2 43.9 5.1 12.2 27.6 8.3 4.0 5.3 20.4 14.2 17.8 31.0 17.8 8.2 23.1 53.6 12.0 6.2 4.9 9.3 6.2 7.3 26.4 12.5 29.6 6.6 8.8 9.2 24.2 17.9 6.6 4.4 9.3 11.1 11.0 5.2 7.0 TES "DKFZP586B2022, TESS-2, TESTIN" ENSG00000135269 "Testin LIM domain protein" Q9UGI8 7 116210506-116258783 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "seminal vesicle: 197.1" "Cell type enhanced" "Detected in many" "Early spermatids: 386.6;Glandular and luminal cells: 283.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "EFO-21: 230.0;hTCEpi: 263.6;SK-BR-3: 267.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA015269, HPA018123" Approved Supported "Plasma membrane,Cell Junctions,Focal adhesion sites,Cytosol" NA NA 34000 "Cluster 2: Granulocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 41: Macrophages - Immune response" "Focal adhesion sites, Cytosol" "Plasma membrane, Cell Junctions" "HPA015269: AB_1857899, HPA018123: AB_1857900" "unprognostic (9.81e-2)" "unprognostic (5.53e-3)" "unprognostic (4.79e-2)" "unprognostic (1.31e-1)" "unprognostic (4.01e-1)" "unprognostic (6.08e-3)" "unprognostic (1.84e-3)" "unprognostic (4.81e-3)" "unprognostic (8.81e-3)" "unprognostic (6.19e-3)" "prognostic unfavorable (1.20e-5)" "unprognostic (1.60e-2)" "prognostic favorable (8.71e-5)" "unprognostic (1.50e-1)" "unprognostic (5.47e-2)" "unprognostic (2.36e-2)" "unprognostic (3.86e-1)" 29.3 7.2 2.7 54.4 2.7 44.1 32.2 3.4 3.6 29.0 10.0 134.7 41.1 105.9 21.7 58.2 45.2 37.4 14.7 2.3 2.9 19.3 10.1 41.0 49.6 6.4 3.5 7.3 20.8 15.3 5.7 25.6 3.4 55.2 69.0 13.4 34.2 197.1 5.1 23.2 47.5 147.6 3.2 30.0 52.1 39.9 4.3 33.5 66.4 8.9 51.3 87.1 41.1 3.0 115.9 24.0 27.0 0.2 11.7 29.7 62.3 58.9 28.9 10.9 10.6 60.4 126.2 0.0 230.0 41.7 1.3 116.9 14.4 87.3 26.4 57.3 46.0 11.5 53.1 30.5 69.9 53.6 0.2 66.4 263.6 37.7 95.0 74.9 31.1 0.0 11.9 39.5 3.0 24.4 0.2 0.7 17.8 134.0 67.4 0.2 0.4 46.0 110.9 44.0 12.4 113.4 85.5 267.1 68.2 77.6 0.3 21.5 52.3 0.6 1.5 86.2 0.7 92.6 48.9 1.3 7.4 27.2 89.3 274.7 79.2 221.5 150.2 132.1 144.7 104.6 113.4 137.6 86.9 95.5 111.0 127.6 41.6 205.1 170.5 20.7 130.4 162.8 2.7 2.7 3.4 3.6 2.3 2.9 6.4 3.5 3.4 3.2 4.3 3.0 40.8 243.6 47.0 0.0 60.4 200.4 196.2 64.8 60.3 2.2 62.2 57.0 16.1 47.1 81.7 36.8 12.5 23.2 121.3 140.8 21.5 110.7 386.6 176.7 29.9 49.0 50.6 17.7 0.1 112.3 78.1 23.6 84.1 283.9 18.9 54.1 25.7 11.9 15.4 1.7 0.1 100.7 34.6 58.0 119.0 112.5 1.8 78.0 28.4 10.3 77.6 24.7 201.8 0.0 0.3 196.8 112.1 0.4 76.3 102.4 65.3 13.6 68.1 13.9 6.6 9.0 42.3 19.1 10.6 55.9 122.7 29.1 79.2 8.8 79.7 135.9 TGFB1I1 "ARA55, Hic-5, TSC-5" ENSG00000140682 "Transforming growth factor beta 1 induced transcript 1" O43294 16 31471585-31477960 "Predicted intracellular proteins" "Differentiation, Wnt signaling pathway" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 265.6;intestine: 264.4" "Cell type enhanced" "Detected in many" "Leydig cells: 92.2;Peritubular cells: 179.0;Sertoli cells: 223.5;Smooth muscle cells: 176.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "basophil: 9.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 9.5" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 100.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB020844 Enhanced Supported "Focal adhesion sites,Cytosol" NA NA 800000 "Cluster 34: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Focal adhesion sites" Cytosol "CAB020844: " "unprognostic (5.80e-2)" "unprognostic (3.09e-2)" "unprognostic (5.34e-2)" "unprognostic (1.18e-1)" "unprognostic (6.64e-2)" "unprognostic (9.52e-2)" "unprognostic (1.89e-1)" "unprognostic (4.95e-2)" "unprognostic (4.19e-2)" "unprognostic (1.71e-2)" "unprognostic (1.38e-1)" "unprognostic (1.39e-1)" "prognostic unfavorable (6.06e-8)" "unprognostic (1.06e-2)" "unprognostic (6.57e-2)" "unprognostic (2.25e-2)" "prognostic unfavorable (7.73e-5)" 65.5 17.0 4.8 22.7 5.1 1.0 52.8 4.6 6.9 119.0 4.4 264.4 14.5 265.6 12.4 38.2 143.2 14.4 48.5 4.6 4.7 26.6 9.7 54.7 4.8 5.6 4.6 78.6 8.2 8.6 8.2 19.7 5.0 87.6 23.9 0.7 21.0 80.8 13.1 28.5 61.7 106.1 4.7 33.0 78.5 10.2 5.1 1.4 26.8 10.5 4.9 171.1 73.6 4.4 13.3 16.6 25.9 0.0 25.4 46.1 0.3 70.8 64.8 43.6 30.1 6.6 4.5 0.0 65.1 62.3 29.1 20.6 6.0 13.3 56.4 0.1 0.3 17.5 29.1 3.7 67.4 0.0 19.8 31.1 18.7 27.5 16.3 100.0 29.2 0.0 1.5 0.0 51.9 0.1 0.0 1.6 1.4 1.4 16.2 0.0 30.9 0.1 12.5 6.6 0.0 19.0 27.5 0.2 14.1 20.9 0.1 1.7 82.4 79.8 19.2 21.4 31.8 0.1 0.1 0.2 34.9 0.8 49.6 9.5 0.0 0.1 0.2 0.0 0.3 0.9 0.9 0.1 0.0 0.2 0.1 0.6 0.2 0.0 0.0 0.3 1.6 1.3 4.8 5.1 4.6 6.9 4.6 4.7 5.6 4.6 5.0 4.7 5.1 4.4 76.9 6.4 4.8 0.0 0.4 12.6 23.9 34.8 14.8 0.4 4.1 71.5 13.4 5.7 3.4 7.3 0.0 1.2 1.5 1.8 7.9 33.3 1.2 3.6 76.2 48.8 0.0 11.0 0.1 22.5 1.2 64.4 4.6 2.9 6.3 35.3 29.6 0.3 14.6 0.0 0.1 4.7 0.0 0.3 15.4 3.3 92.2 9.3 40.9 2.8 4.2 7.0 0.0 3.5 0.1 28.4 2.2 179.0 1.4 20.1 13.3 19.7 1.1 1.4 223.5 17.4 176.0 1.5 3.6 1.9 11.2 1.8 2.6 20.3 5.3 4.6 TLE2 "ESG, ESG2, FLJ41188, GRG2" ENSG00000065717 "TLE family member 2, transcriptional corepressor" Q04725 19 2997639-3047635 "Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.7" "Group enriched" "Detected in many" 11 "B-cells: 1.7;T-cells: 1.2" "Cell line enhanced" "Detected in many" "AN3-CA: 44.4;RT4: 35.2;T-47d: 25.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049103 Enhanced Supported "Nuclear bodies,Focal adhesion sites" NA NA "Cluster 37: B-cells - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 56: Bipolar cells - Visual perception" "Nuclear bodies" "Focal adhesion sites" "HPA049103: AB_2680631" "unprognostic (1.87e-3)" "unprognostic (1.42e-1)" "unprognostic (2.89e-1)" "prognostic favorable (2.51e-4)" "unprognostic (2.23e-1)" "unprognostic (1.01e-1)" "unprognostic (9.87e-3)" "unprognostic (6.40e-3)" "unprognostic (2.44e-1)" "unprognostic (1.81e-2)" "prognostic favorable (2.39e-6)" "unprognostic (2.12e-1)" "prognostic favorable (9.49e-6)" "unprognostic (2.66e-1)" "unprognostic (5.99e-2)" "unprognostic (2.60e-1)" "prognostic favorable (8.88e-4)" 35.6 31.5 19.4 5.2 20.6 1.6 34.2 67.6 21.2 45.0 10.5 52.4 12.5 62.6 5.2 13.5 62.2 9.0 75.6 13.4 18.9 52.0 17.1 42.5 5.5 22.0 21.5 29.3 36.7 20.4 25.9 9.3 27.2 55.5 6.6 8.7 85.5 28.0 66.4 21.9 18.4 11.1 18.5 46.9 30.2 23.0 27.9 4.9 72.5 30.9 2.1 67.4 25.7 22.2 0.5 2.8 0.2 44.4 6.7 1.1 9.5 0.4 0.0 2.1 1.1 14.0 5.1 0.2 5.9 3.2 1.3 7.6 7.7 2.7 0.5 1.2 2.1 0.0 3.4 0.6 8.6 0.0 0.4 9.6 1.2 4.9 0.1 2.6 18.0 12.6 16.2 0.2 0.3 15.0 0.4 0.2 0.1 1.3 2.9 3.9 2.2 4.4 5.5 35.2 2.3 11.1 3.0 22.0 1.1 0.9 25.1 0.1 11.7 14.0 14.4 0.8 0.5 0.5 0.5 3.0 0.3 3.3 2.8 0.0 0.0 0.1 1.1 0.0 0.9 1.7 0.7 0.4 0.0 0.1 1.2 0.7 0.0 0.0 0.0 0.0 0.2 0.3 19.4 20.6 67.6 21.2 13.4 18.9 22.0 21.5 27.2 18.5 27.9 22.2 27.1 19.2 17.6 1.6 0.7 3.6 34.2 8.3 11.4 36.9 27.0 16.5 24.9 12.8 7.0 36.8 2.1 1.8 2.8 21.7 1.9 11.3 6.5 1.8 9.6 10.3 13.8 0.4 10.3 2.7 4.4 14.8 8.2 6.0 0.0 7.2 16.1 4.0 0.7 1.7 29.3 14.9 8.2 0.3 3.1 18.8 11.8 1.1 5.4 3.7 0.1 19.2 2.1 10.6 14.6 2.7 9.8 15.1 0.3 28.2 1.3 1.1 10.0 4.4 0.0 1.5 11.2 1.2 5.8 4.6 2.3 6.7 2.3 0.7 26.5 32.5 TLN1 "ILWEQ, TLN" ENSG00000137076 "Talin 1" Q9Y490 9 35696948-35732195 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Macrophages: 323.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002006, HPA004748" Supported Supported "Plasma membrane,Focal adhesion sites,Centriolar satellite,Cytosol" NA NA 1300000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" "Focal adhesion sites, Cytosol" "Plasma membrane, Centriolar satellite" "CAB002006: , HPA004748: AB_1857760" "unprognostic (9.71e-2)" "unprognostic (2.02e-2)" "prognostic unfavorable (5.56e-4)" "unprognostic (1.96e-1)" "unprognostic (5.55e-2)" "unprognostic (2.52e-1)" "unprognostic (3.18e-2)" "unprognostic (5.07e-2)" "unprognostic (1.94e-1)" "unprognostic (6.46e-2)" "unprognostic (1.82e-1)" "unprognostic (1.27e-1)" "prognostic favorable (7.21e-4)" "unprognostic (1.36e-1)" "unprognostic (2.71e-2)" "unprognostic (7.83e-2)" "unprognostic (8.83e-3)" 125.7 62.7 31.1 84.7 42.1 79.2 79.4 39.3 31.1 80.0 43.1 196.2 36.5 151.8 25.3 78.0 102.9 53.2 81.2 26.2 34.9 47.3 42.3 91.8 63.1 50.8 41.9 66.0 33.1 41.6 36.7 70.4 49.7 72.6 41.4 7.7 42.5 111.4 70.9 46.7 77.9 145.4 41.5 89.7 91.8 23.3 44.9 61.1 49.0 55.8 52.7 147.7 66.3 44.6 63.4 103.8 62.7 86.9 210.8 158.7 71.4 171.2 186.8 162.9 146.4 86.3 27.4 76.5 55.5 319.0 103.0 33.3 74.2 106.9 118.3 172.8 48.0 173.0 132.1 77.4 130.6 105.8 276.2 193.4 50.2 240.1 112.7 223.7 253.4 64.7 60.2 76.0 218.5 27.8 71.5 27.8 51.3 28.4 78.8 95.0 36.6 44.8 81.4 49.8 14.1 59.6 83.7 46.3 53.4 56.5 39.3 72.6 308.5 257.8 99.6 80.0 140.6 26.2 27.6 51.7 199.9 55.9 238.4 6.0 5.9 7.3 5.4 6.1 4.4 2.6 3.1 4.1 4.3 2.3 1.4 3.1 10.0 4.1 8.1 5.4 2.3 6.9 31.1 42.1 39.3 31.1 26.2 34.9 50.8 41.9 49.7 41.5 44.9 44.6 123.2 109.0 66.9 11.4 99.8 40.1 69.4 43.5 42.7 11.7 40.3 61.3 134.1 31.5 55.7 53.3 10.4 44.3 186.3 43.8 23.5 94.3 47.2 36.0 156.9 106.8 34.1 127.0 7.7 61.9 82.6 103.9 51.0 73.0 206.6 72.0 93.9 54.7 112.4 15.2 7.6 29.0 26.4 196.9 91.0 26.4 99.4 323.4 23.2 21.5 174.1 33.0 288.4 4.5 9.1 107.7 33.2 128.6 61.4 58.4 40.6 62.8 34.3 17.6 203.8 126.5 267.9 32.0 28.5 47.4 26.6 58.8 143.8 89.4 28.9 46.4 TLN2 "ILWEQ, KIAA0320" ENSG00000171914 "Talin 2" Q9Y4G6 15 62390526-62844631 "Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 38.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 153.7;Inhibitory neurons: 127.2;Microglial cells: 139.6;Oligodendrocyte precursor cells: 108.6;Oligodendrocytes: 93.6;Skeletal myocytes: 135.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 59.3;hTERT-HME1: 48.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017194, HPA051828, HPA054787" Enhanced Supported "Focal adhesion sites,Cytosol" NA NA 46000000 "Cluster 39: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Focal adhesion sites, Cytosol" "CAB017194: , HPA051828: AB_2732570, HPA054787: AB_2732587" "prognostic favorable (6.53e-4)" "unprognostic (2.61e-1)" "unprognostic (9.47e-2)" "unprognostic (8.95e-2)" "unprognostic (3.74e-1)" "unprognostic (1.43e-1)" "unprognostic (8.24e-2)" "unprognostic (9.94e-2)" "unprognostic (1.68e-1)" "unprognostic (6.02e-2)" "unprognostic (2.81e-2)" "unprognostic (1.91e-1)" "prognostic favorable (1.81e-6)" "prognostic favorable (7.74e-4)" "unprognostic (1.34e-1)" "unprognostic (5.79e-2)" "unprognostic (2.30e-1)" 19.0 4.1 14.2 2.2 15.6 3.8 10.4 3.2 16.9 8.0 20.2 9.3 4.7 3.7 2.1 2.1 4.3 1.9 12.1 18.3 8.2 38.4 4.8 2.4 0.5 7.6 8.2 4.6 4.7 2.4 5.5 1.2 6.2 2.3 7.3 7.7 7.8 2.1 26.1 3.6 5.1 2.9 11.2 1.3 5.5 5.4 7.0 3.1 13.0 12.2 0.5 4.1 4.2 13.8 1.8 5.6 8.0 9.4 59.3 5.6 9.0 13.7 10.8 12.4 12.2 15.1 1.9 4.8 6.2 24.0 20.5 2.4 10.3 2.2 10.8 15.2 1.0 0.6 22.8 10.1 2.0 1.6 0.4 10.3 5.6 16.6 48.9 7.1 0.5 5.7 0.6 0.2 21.0 7.5 0.7 0.6 14.2 26.3 4.1 5.8 20.3 5.8 6.5 11.6 1.9 9.3 10.6 1.1 3.5 17.1 2.9 3.6 3.9 22.2 30.0 36.3 35.6 0.3 0.9 3.1 10.1 3.4 27.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.2 15.6 3.2 16.9 18.3 8.2 7.6 8.2 6.2 11.2 7.0 13.8 11.5 0.0 3.2 50.6 1.1 2.4 1.8 0.7 1.2 18.6 16.5 10.2 41.1 5.7 0.9 27.6 37.5 1.2 0.7 39.0 11.7 3.5 4.3 10.9 14.3 9.0 2.4 37.7 153.7 3.9 29.7 21.5 40.8 17.4 0.0 9.3 3.3 12.6 4.9 48.8 127.2 20.0 6.1 6.2 3.1 5.2 11.8 5.5 0.0 139.6 0.8 11.1 1.0 108.6 93.6 3.7 21.0 15.8 0.7 1.5 14.6 35.1 0.1 48.3 0.0 135.6 12.3 6.7 24.5 3.1 1.6 1.4 1.3 25.8 37.7 1.7 TM4SF20 "FLJ22800, TCCE518" ENSG00000168955 "Transmembrane 4 L six family member 20" Q53R12 2 227362038-227381995 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Autism spectrum disorder" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 76 "intestine: 266.6" "Cell type enriched" "Detected in some" 4 "Proximal enterocytes: 703.0" "Group enriched" "Detected in many" 6 "colorectal cancer: 5.0;liver cancer: 4.7;pancreatic cancer: 5.5;stomach cancer: 11.8" "Region enhanced" "Detected in single" "cerebellum: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 2.6;RPMI-8226: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA051838, HPA063184, HPA065531" Uncertain Supported "Plasma membrane,Focal adhesion sites" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 56: Intestine - Transmembrane transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 45: Enterocytes - Digestion" "Plasma membrane, Focal adhesion sites" "HPA051838: AB_2681631, HPA063184: AB_2684958, HPA065531: AB_2685506" "unprognostic (4.68e-2)" "unprognostic (1.13e-1)" "unprognostic (8.75e-2)" "unprognostic (4.96e-2)" "unprognostic (2.84e-2)" "unprognostic (1.63e-1)" "unprognostic (2.51e-1)" "unprognostic (2.36e-1)" "unprognostic (2.95e-1)" "unprognostic (1.20e-2)" "unprognostic (1.19e-1)" "unprognostic (3.44e-3)" "unprognostic (7.76e-2)" "unprognostic (2.60e-2)" "unprognostic (3.04e-3)" 0.1 0.1 0.2 0.3 0.2 0.2 0.0 1.2 0.4 0.0 0.4 3.1 266.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 3.9 0.3 0.0 0.0 0.0 0.3 144.5 1.6 0.0 0.1 0.5 3.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 2.6 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.6 0.1 0.0 0.0 0.1 0.0 1.7 0.0 0.1 0.2 0.6 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.7 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.2 0.2 1.2 0.4 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 15.1 0.0 0.0 48.4 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 21.4 0.0 0.0 0.0 77.3 0.0 0.1 0.0 0.0 0.0 0.2 0.0 1.0 0.5 0.0 157.9 0.7 0.0 0.0 703.0 0.0 0.0 0.3 0.0 0.1 0.0 0.5 0.3 0.0 0.0 0.0 0.1 0.0 18.8 0.0 TMEM139 FLJ90586 ENSG00000178826 "Transmembrane protein 139" Q8IV31 7 143279957-143288048 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 33.8;kidney: 32.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 51.5;Ductal cells: 49.0;Proximal enterocytes: 90.7;Proximal tubular cells: 89.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 22.4;CAPAN-2: 40.8;EFO-21: 27.9;RPTEC TERT1: 70.5;SK-BR-3: 25.0;T-47d: 68.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA036982, HPA036983" Approved Approved "Plasma membrane,Focal adhesion sites" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "Focal adhesion sites" "HPA036982: AB_2675413, HPA036983: AB_10672275" "unprognostic (2.58e-1)" "unprognostic (4.38e-1)" "unprognostic (6.62e-3)" "unprognostic (1.41e-1)" "unprognostic (2.10e-1)" "unprognostic (2.16e-3)" "unprognostic (2.83e-2)" "unprognostic (4.90e-2)" "unprognostic (1.60e-1)" "unprognostic (2.82e-2)" "prognostic unfavorable (1.66e-4)" "unprognostic (2.89e-1)" "prognostic favorable (3.05e-5)" "unprognostic (1.73e-1)" "unprognostic (1.42e-2)" "unprognostic (2.83e-2)" "unprognostic (9.08e-3)" 1.1 2.7 1.9 2.2 6.4 0.0 3.2 6.6 3.2 8.9 2.9 5.7 33.8 1.2 1.3 0.4 6.8 7.2 3.3 1.6 4.1 32.2 9.2 5.1 0.2 10.5 6.9 0.4 8.7 6.8 1.8 5.2 8.9 0.9 4.5 0.8 4.8 3.1 0.1 1.2 19.3 0.4 5.9 0.9 2.5 3.8 5.7 0.0 7.2 0.0 0.1 1.8 0.3 13.9 22.4 1.6 0.3 0.1 0.0 0.0 14.3 0.2 0.0 0.0 0.0 5.2 40.8 0.3 27.9 0.0 1.8 18.5 0.0 9.3 0.0 0.3 0.0 0.0 2.4 3.1 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.9 0.0 1.3 0.0 0.5 0.0 1.5 1.6 1.0 0.0 0.5 1.6 0.4 0.3 0.0 70.5 5.6 0.4 0.1 1.1 25.0 0.2 0.5 68.5 0.0 0.0 0.3 0.7 0.0 0.1 0.0 0.1 0.3 0.3 0.3 0.3 0.0 0.0 0.2 0.0 0.8 0.0 0.1 0.3 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.8 0.0 0.6 0.1 1.9 6.4 6.6 3.2 1.6 4.1 10.5 6.9 8.9 5.9 5.7 13.9 0.6 16.0 5.9 0.7 0.2 0.1 2.1 2.8 0.0 0.2 8.2 15.5 2.3 27.1 5.4 51.5 0.0 30.5 0.2 28.9 35.2 49.0 14.8 16.2 1.6 0.7 3.6 0.0 0.0 4.7 5.2 0.4 3.1 17.9 0.0 2.2 1.4 16.2 1.9 0.0 0.2 6.7 0.0 0.6 0.3 13.6 0.0 0.7 5.4 0.0 1.1 7.7 0.0 0.0 5.2 30.6 23.3 0.0 0.0 1.2 90.7 89.1 3.8 0.1 0.0 0.0 0.9 0.1 0.2 0.6 0.0 6.4 0.8 0.7 12.9 1.4 TMEM260 "C14orf101, FLJ20392" ENSG00000070269 "Transmembrane protein 260" Q9NX78 14 56488354-56650606 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 39.8" "Cell type enhanced" "Detected in many" "Early spermatids: 88.5;Excitatory neurons: 66.7;Inhibitory neurons: 62.8;Oligodendrocyte precursor cells: 69.9;Oligodendrocytes: 106.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003502 Uncertain Approved "Nucleoplasm,Focal adhesion sites,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoplasm, Cytosol" "Focal adhesion sites" "HPA003502: AB_1078314" "unprognostic (4.63e-2)" "unprognostic (2.41e-2)" "unprognostic (1.98e-1)" "unprognostic (1.73e-2)" "unprognostic (2.51e-1)" "unprognostic (3.58e-2)" "unprognostic (2.04e-1)" "prognostic favorable (7.11e-4)" "unprognostic (7.14e-2)" "unprognostic (1.89e-1)" "unprognostic (1.95e-3)" "unprognostic (3.22e-1)" "unprognostic (2.23e-3)" "unprognostic (5.81e-2)" "unprognostic (8.11e-2)" "unprognostic (1.32e-1)" "unprognostic (3.84e-2)" 4.6 4.3 4.5 4.0 5.4 2.1 5.5 4.7 4.9 39.8 12.4 5.8 5.2 6.2 7.8 3.4 7.4 5.9 2.5 4.4 4.5 6.8 5.6 4.4 4.7 4.6 4.4 9.3 4.5 7.3 3.7 5.7 4.5 5.2 5.8 6.9 3.8 4.5 2.2 5.6 5.7 3.9 4.4 4.0 5.5 5.2 4.5 5.8 8.4 2.2 3.8 4.7 3.6 7.3 8.0 5.5 4.2 8.9 14.5 11.9 8.2 8.4 9.2 5.4 6.4 2.6 5.8 6.5 8.0 6.2 6.1 9.1 9.7 6.1 8.4 8.1 4.9 4.2 2.7 3.6 10.2 5.9 9.6 14.6 10.7 3.0 10.3 9.8 7.1 4.9 5.2 6.8 7.1 5.3 3.1 2.2 3.9 13.0 8.6 4.3 6.7 2.2 9.0 11.7 8.8 4.3 9.4 6.7 5.5 7.8 8.6 9.0 10.0 10.9 4.1 8.2 4.2 4.1 3.5 3.8 6.8 4.3 5.5 0.0 1.1 1.2 1.3 0.8 0.9 0.7 0.8 0.7 0.9 0.7 1.2 0.8 0.5 2.5 0.7 1.9 1.3 0.8 4.5 5.4 4.7 4.9 4.4 4.5 4.6 4.4 4.5 4.4 4.5 7.3 12.2 19.2 17.2 39.8 13.0 5.4 7.1 5.9 5.7 14.6 8.0 7.7 3.7 2.8 8.5 22.0 4.2 10.2 9.8 9.4 1.9 8.1 88.5 22.8 17.6 8.3 18.0 7.6 66.7 3.8 7.7 10.4 9.2 29.1 12.0 20.0 8.9 13.3 6.5 6.7 62.8 10.0 6.1 12.8 5.0 31.5 15.2 8.7 1.8 39.4 11.1 5.2 14.4 69.9 106.0 5.6 7.6 10.9 9.3 9.3 9.5 4.8 14.2 16.4 0.0 7.0 8.0 9.3 11.0 10.0 5.5 11.1 8.9 14.5 12.1 8.0 TMEM35A "FLJ14084, NACHO, TMEM35, TUF-1" ENSG00000126950 "Transmembrane protein 35A" Q53FP2 X 101078879-101096367 "Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 71.9;intestine: 36.8;seminal vesicle: 50.9" "Cell type enriched" "Detected in some" 5 "Theca cells: 37.5" "Cancer enhanced" "Detected in many" "glioma: 6.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 10.1;HUVEC TERT2: 52.5;SH-SY5Y: 13.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048583 Enhanced Supported Supported "Vesicles,Focal adhesion sites,Cytosol" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 52: Non-specific - Transcription" Vesicles "Focal adhesion sites, Cytosol" "HPA048583: AB_2680451" "unprognostic (7.98e-2)" "unprognostic (7.22e-2)" "unprognostic (1.21e-2)" "unprognostic (1.35e-2)" "unprognostic (3.02e-2)" "unprognostic (3.89e-3)" "unprognostic (2.77e-2)" "unprognostic (6.66e-3)" "unprognostic (1.05e-1)" "unprognostic (3.34e-3)" "unprognostic (9.20e-2)" "unprognostic (4.72e-2)" "unprognostic (3.49e-4)" "unprognostic (5.91e-2)" "unprognostic (1.85e-1)" "unprognostic (1.48e-2)" "unprognostic (9.37e-3)" 3.5 6.9 20.8 1.3 20.4 0.0 0.8 18.5 28.5 4.6 2.5 36.8 3.4 7.8 3.6 11.2 4.1 3.4 0.5 28.4 71.9 0.5 0.0 2.3 0.1 21.8 21.3 7.9 0.2 12.7 2.2 0.1 36.8 22.3 9.6 10.2 0.5 50.9 0.8 0.6 7.2 10.3 15.6 0.8 5.2 1.4 47.5 0.2 0.8 2.5 0.3 9.7 4.4 13.5 0.0 0.0 5.4 0.0 3.9 10.1 0.0 1.1 0.7 0.4 0.2 0.0 0.0 0.0 0.1 3.2 0.0 0.0 3.4 0.0 1.0 0.0 0.2 0.0 0.1 0.0 1.2 0.0 0.0 3.5 0.0 1.9 0.0 7.5 52.5 0.0 0.0 0.1 6.6 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.3 13.2 0.0 0.0 0.0 1.3 0.0 0.0 1.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.8 20.4 18.5 28.5 28.4 71.9 21.8 21.3 36.8 15.6 47.5 13.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 7.4 0.4 0.0 0.0 0.0 0.0 0.1 3.0 0.0 0.2 0.0 6.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.1 37.5 0.0 0.0 TMEM52B "C12orf59, FLJ31166" ENSG00000165685 "Transmembrane protein 52B" Q4KMG9 12 10170542-10191801 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "kidney: 175.8" "Cell type enriched" "Detected in some" 15 "Distal tubular cells: 712.1" "Cancer enriched" "Detected in some" 5 "renal cancer: 6.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "CACO-2: 95.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA058096 Enhanced Approved "Focal adhesion sites" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "Focal adhesion sites" "HPA058096: AB_2683603" "unprognostic (1.10e-2)" "unprognostic (7.61e-2)" "unprognostic (1.37e-3)" "unprognostic (1.22e-1)" "unprognostic (1.67e-1)" "unprognostic (5.33e-3)" "unprognostic (1.37e-1)" "unprognostic (8.65e-2)" "unprognostic (7.14e-4)" "unprognostic (2.23e-1)" "unprognostic (6.36e-2)" "unprognostic (7.33e-2)" "unprognostic (3.24e-2)" "unprognostic (5.80e-2)" "unprognostic (5.51e-2)" "unprognostic (1.66e-1)" "unprognostic (3.18e-1)" 0.1 0.1 0.6 0.8 0.9 3.4 0.3 0.8 0.9 0.1 0.9 0.1 0.2 0.0 0.3 0.0 0.1 0.4 0.0 0.7 0.7 175.8 0.2 0.7 0.2 1.3 0.8 0.0 0.3 0.1 0.0 6.0 1.2 0.1 0.1 0.1 1.9 0.0 0.0 0.4 0.2 0.4 1.0 0.1 0.4 0.3 1.2 0.1 0.2 0.0 0.2 0.2 0.0 1.6 2.3 0.1 0.0 0.1 0.0 0.0 1.1 2.2 0.0 0.1 0.0 95.9 0.1 0.0 0.1 0.7 4.9 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 11.7 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 4.1 0.0 0.0 7.0 8.9 0.0 3.0 5.0 1.4 0.0 0.2 0.4 0.0 0.0 0.1 0.1 0.1 0.2 4.7 0.0 0.4 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.9 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.6 0.9 0.8 0.9 0.7 0.7 1.3 0.8 1.2 1.0 1.2 1.6 0.1 0.0 0.5 0.3 0.5 0.1 0.0 0.0 0.0 0.0 0.2 0.5 0.3 0.0 0.0 12.9 0.0 44.7 0.0 0.1 712.1 0.0 0.6 0.0 0.1 0.2 0.0 0.0 0.8 0.0 2.5 3.2 0.0 0.1 0.0 0.0 0.0 0.0 10.8 0.0 0.2 0.0 0.0 0.8 1.1 0.1 0.3 4.2 1.8 2.8 1.7 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.3 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.0 19.4 0.1 0.0 0.0 0.1 TMEM53 "FLJ22353, NET4" ENSG00000126106 "Transmembrane protein 53" Q6P2H8 1 44635238-44674481 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 59.5" "Cell type enriched" "Detected in many" 5 "Late spermatids: 999.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "plasmacytoid DC: 99.4" "Lineage enriched" "Detected in all" 4 "dendritic cells: 99.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021134 Approved Approved "Golgi apparatus,Focal adhesion sites" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "Golgi apparatus" "Focal adhesion sites" "HPA021134: AB_2205162" "unprognostic (5.28e-2)" "unprognostic (2.60e-1)" "unprognostic (5.37e-2)" "unprognostic (4.62e-2)" "unprognostic (3.93e-2)" "unprognostic (1.14e-1)" "unprognostic (2.82e-2)" "unprognostic (2.88e-2)" "unprognostic (2.19e-2)" "prognostic favorable (6.96e-4)" "unprognostic (3.00e-1)" "unprognostic (1.34e-1)" "prognostic favorable (1.02e-5)" "unprognostic (1.15e-3)" "unprognostic (1.84e-2)" "unprognostic (4.07e-2)" "unprognostic (2.29e-2)" 12.8 12.0 5.7 4.4 9.2 6.7 12.1 6.8 8.3 6.8 6.3 14.2 16.4 8.9 6.8 6.0 7.0 6.2 13.9 5.7 7.2 18.3 59.5 10.5 4.0 8.5 8.5 10.6 8.3 6.3 10.1 3.9 8.5 7.2 6.9 7.1 7.2 3.3 7.6 6.6 14.6 4.2 5.8 6.3 10.1 34.9 8.8 3.3 7.9 3.7 2.1 7.5 6.1 15.4 12.9 14.7 13.0 9.6 16.6 12.5 15.6 3.8 11.1 7.2 10.5 4.7 39.9 4.1 11.8 3.6 27.4 11.5 3.6 7.8 3.8 6.5 9.2 4.7 6.0 22.7 16.5 3.7 16.6 14.8 11.9 14.4 3.1 7.9 4.0 9.1 2.0 5.1 4.3 7.7 4.5 11.2 7.6 9.9 8.5 6.8 1.8 40.0 21.6 13.4 9.0 8.7 4.1 15.7 21.3 9.3 4.8 9.9 1.7 5.3 8.8 7.5 4.7 3.7 4.7 2.3 13.6 9.6 6.3 14.1 12.9 6.3 7.3 23.1 6.3 13.9 7.4 6.3 6.6 14.8 3.5 4.5 1.4 7.8 16.2 99.4 8.1 7.6 5.7 9.2 6.8 8.3 5.7 7.2 8.5 8.5 8.5 5.8 8.8 15.4 10.9 6.4 12.0 8.1 3.5 1.7 9.5 24.2 1.8 6.9 9.0 7.6 35.5 10.0 20.4 20.2 4.2 14.5 9.5 53.1 45.0 18.6 188.3 14.0 4.6 8.5 14.4 10.1 2.9 25.7 15.5 6.9 8.2 5.7 6.3 8.6 10.0 93.0 34.3 18.5 3.6 22.6 44.7 12.6 0.7 999.9 9.0 14.0 8.8 1.9 3.8 17.1 5.2 3.0 4.8 17.5 51.3 12.4 2.6 8.9 74.3 45.9 32.8 13.8 26.3 3.7 10.6 15.6 13.2 3.9 2.3 9.3 3.7 8.3 18.0 12.7 TNFRSF25 "APO-3, DDR3, DR3, LARD, TNFRSF12, TR3, TRAMP, WSL-1, WSL-LR" ENSG00000215788 "TNF receptor superfamily member 25" Q93038 1 6460786-6466175 "Predicted membrane proteins, Predicted secreted proteins" Apoptosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 44.0;pituitary gland: 29.9;skin 1: 25.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 34.1;Excitatory neurons: 37.5;T-cells: 41.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "MAIT T-cell: 5.6;memory CD4 T-cell: 4.4;memory CD8 T-cell: 2.2;naive CD4 T-cell: 4.4;T-reg: 7.9" "Lineage enriched" "Detected in many" 7 "T-cells: 7.9" "Cell line enhanced" "Detected in many" "HDLM-2: 20.5;RPMI-8226: 25.7" "Group enriched" "Detected in some" 6 "amygdala: 1.2;cerebral cortex: 1.4;hippocampal formation: 2.0" "Not detected" "Not detected" HPA069834 Approved "Nucleoplasm,Plasma membrane,Actin filaments,Focal adhesion sites" "Secreted - unknown location" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Actin filaments, Focal adhesion sites" Nucleoplasm "HPA069834: " "unprognostic (8.09e-3)" "unprognostic (6.91e-3)" "prognostic unfavorable (4.46e-4)" "unprognostic (1.97e-1)" "unprognostic (9.63e-3)" "prognostic favorable (3.09e-4)" "unprognostic (2.16e-1)" "unprognostic (1.46e-1)" "unprognostic (2.04e-1)" "unprognostic (2.07e-1)" "unprognostic (6.01e-2)" "unprognostic (3.98e-2)" "prognostic unfavorable (1.65e-7)" "unprognostic (1.21e-1)" "unprognostic (1.61e-1)" "unprognostic (3.44e-1)" "unprognostic (8.68e-3)" 6.4 4.2 4.0 3.2 4.0 0.8 4.0 11.1 6.1 5.2 4.9 6.1 3.0 3.0 0.6 10.3 5.7 2.2 8.7 4.8 4.3 3.3 1.2 2.4 4.3 3.7 3.6 3.1 1.5 0.9 29.9 4.4 4.4 5.2 1.4 1.2 3.3 2.3 1.1 25.3 5.0 0.5 3.3 44.0 2.0 0.9 3.7 2.0 3.2 1.2 2.7 2.5 4.6 3.5 1.8 0.4 1.1 2.0 0.0 0.6 1.3 1.5 0.6 0.3 0.0 1.7 2.8 0.0 2.5 0.0 1.3 4.2 0.6 4.7 0.0 20.5 1.5 0.6 1.7 0.1 0.7 0.0 0.1 0.0 3.2 1.5 4.1 2.7 4.0 1.1 0.0 0.0 0.0 2.2 0.0 8.0 1.4 1.4 3.4 0.6 0.3 25.7 1.3 0.7 3.4 5.3 0.0 2.5 0.1 0.6 2.0 2.9 2.5 1.3 2.1 0.0 2.0 0.0 3.5 0.0 2.4 0.0 0.0 0.0 0.0 0.0 1.0 0.2 5.6 0.0 4.4 2.2 0.5 0.0 4.4 0.7 0.0 0.8 1.0 0.0 7.9 0.9 4.0 4.0 11.1 6.1 4.8 4.3 3.7 3.6 4.4 3.3 3.7 3.5 19.0 3.2 5.0 3.9 2.5 24.6 2.3 5.6 11.4 3.1 4.2 5.5 1.1 1.5 3.3 1.8 2.1 0.7 12.8 34.1 0.0 0.2 0.2 4.1 11.2 11.5 6.7 3.0 37.5 0.4 2.0 2.3 5.6 6.9 7.0 4.8 7.9 1.1 4.0 5.0 21.6 20.3 0.0 1.2 6.6 0.3 2.8 4.0 7.2 14.0 3.0 10.2 10.3 7.5 2.1 1.4 16.0 9.4 3.2 3.7 9.8 0.6 4.8 9.1 0.0 2.6 2.6 0.4 1.2 8.6 28.6 0.1 41.4 0.7 25.0 6.8 TNFSF13B "BAFF, BLYS, CD257, TALL-1, TALL1, THANK, TNFSF20" ENSG00000102524 "TNF superfamily member 13b" Q9Y275 13 108251240-108308484 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 25.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 87.5;Kupffer cells: 141.1;Langerhans cells: 246.7;Macrophages: 170.4;monocytes: 509.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 505.4" "Group enriched" "Detected in all" 11 "dendritic cells: 206.4;granulocytes: 505.4;monocytes: 350.9" "Cell line enriched" "Detected in some" 7 "U-937: 167.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB009188, HPA030526" Enhanced Supported "Vesicles,Plasma membrane,Focal adhesion sites" "Secreted to blood" NA NA 393000 790000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "Vesicles, Focal adhesion sites" "CAB009188: , HPA030526: " "unprognostic (6.48e-2)" "unprognostic (3.05e-3)" "unprognostic (1.38e-1)" "unprognostic (1.90e-1)" "unprognostic (2.61e-2)" "unprognostic (7.99e-2)" "unprognostic (8.19e-2)" "unprognostic (1.37e-1)" "unprognostic (1.63e-1)" "unprognostic (1.02e-2)" "unprognostic (2.64e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (2.53e-11)" "unprognostic (1.23e-1)" "unprognostic (4.14e-2)" "unprognostic (1.88e-1)" "unprognostic (1.25e-1)" 8.2 5.3 2.8 25.9 2.6 20.1 4.7 2.7 4.1 2.2 5.8 5.5 10.7 1.4 1.5 4.8 2.4 12.4 3.8 2.7 3.1 1.5 5.3 10.9 20.9 6.3 3.0 1.1 1.5 0.7 1.0 9.0 4.2 1.7 8.4 0.4 3.3 1.2 1.4 1.9 6.4 5.0 4.6 15.9 5.0 1.2 3.5 5.3 3.0 1.6 17.7 11.1 2.1 5.2 0.1 0.4 0.1 0.1 0.7 0.8 0.2 0.3 0.8 0.6 2.1 0.1 1.7 0.3 0.2 0.2 0.3 0.1 0.0 0.1 0.1 11.6 0.0 0.9 0.4 0.0 0.4 10.2 0.3 2.0 0.4 0.2 0.1 0.4 0.1 0.1 0.1 0.6 1.2 0.0 0.1 5.3 0.1 1.1 0.0 0.0 0.2 0.0 0.6 0.3 1.3 0.3 0.0 0.0 0.4 0.2 0.1 22.3 0.2 0.3 0.0 0.0 0.4 10.0 0.3 0.1 10.3 167.0 1.7 12.6 350.9 100.1 5.4 272.3 31.5 4.4 21.5 4.4 206.4 7.1 9.9 3.4 505.4 5.0 234.1 77.8 19.4 165.8 2.8 2.6 2.7 4.1 2.7 3.1 6.3 3.0 4.2 4.6 3.5 5.2 3.1 16.0 12.9 6.2 7.0 7.1 0.7 1.3 1.2 0.9 2.4 3.2 0.6 10.0 4.2 5.5 0.0 0.5 40.6 0.6 1.9 2.3 1.2 0.4 0.7 3.6 1.2 14.5 18.1 32.5 1.1 29.6 3.1 0.5 5.1 0.9 3.9 2.8 87.5 0.0 11.2 0.9 0.0 141.1 246.7 0.6 5.3 170.4 8.8 15.0 509.4 0.2 5.2 55.3 5.1 1.7 0.5 1.9 1.5 2.7 2.2 1.3 2.0 0.3 6.6 1.4 4.1 0.1 0.7 0.5 4.7 1.1 10.5 1.2 1.8 3.1 TNNT2 "CMD1D, CMH2, CMPD2" ENSG00000118194 "Troponin T2, cardiac type" P45379 1 201359008-201377764 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Muscle protein" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 205 "heart muscle: 10670.6" "Cell type enriched" "Detected in many" 32 "Cardiomyocytes: 12561.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 18 "RH-30: 1077.7" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebral cortex: 3.8" "CAB015371, HPA015774, HPA017888" Enhanced Approved "Nucleoplasm,Nucleoli,Focal adhesion sites,Microtubules" No No 57000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Nucleoli" "Focal adhesion sites, Microtubules" "CAB015371: AB_630390, HPA015774: AB_1858354, HPA017888: AB_1858355" "unprognostic (1.45e-1)" "unprognostic (2.74e-1)" "unprognostic (2.33e-4)" "unprognostic (1.85e-1)" "unprognostic (7.29e-2)" "unprognostic (1.79e-1)" "unprognostic (1.80e-1)" "unprognostic (1.24e-1)" "unprognostic (1.42e-1)" "unprognostic (2.91e-2)" "unprognostic (1.38e-1)" "unprognostic (8.63e-2)" "unprognostic (5.50e-3)" "unprognostic (2.94e-1)" "unprognostic (1.61e-1)" "unprognostic (4.76e-2)" "unprognostic (9.98e-2)" 2.2 4.9 12.4 0.6 13.9 0.1 11.9 11.7 20.4 2.3 11.7 1.3 0.3 3.2 0.8 7.8 1.9 3.8 10670.6 16.8 11.6 51.9 2.3 22.0 2.7 11.6 11.6 1.3 5.0 0.0 4.5 10.3 11.6 6.1 0.1 0.4 3.6 0.7 16.5 21.7 1.6 0.1 11.6 0.7 2.0 1.7 11.6 2.1 2.0 9.4 0.5 19.3 5.0 15.8 0.0 0.0 0.8 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 2.0 0.4 0.0 0.5 0.0 0.0 6.7 0.0 0.4 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.5 0.0 44.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.1 1.1 0.0 0.0 2.2 3.3 0.0 0.0 1077.7 0.0 0.7 0.4 1.1 0.8 0.1 2.0 0.0 61.2 0.0 0.0 0.0 0.0 35.5 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 13.9 11.7 20.4 16.8 11.6 11.6 11.6 11.6 11.6 11.6 15.8 0.6 3.2 3.0 0.3 0.0 3.4 1.4 1.7 1.8 3.9 0.9 1.7 12561.8 0.0 1.1 1.8 0.0 3.5 0.0 2.3 0.0 0.4 11.6 1.2 0.2 93.3 0.0 0.0 9.4 0.4 1.2 385.3 1.1 2.4 0.0 0.0 0.0 0.0 3.1 0.0 0.5 1.7 0.0 0.0 0.8 19.3 0.6 0.3 0.0 1.9 2.6 0.0 0.0 0.5 0.7 1.2 1.4 1.2 0.0 2.1 0.8 0.9 0.7 0.6 0.0 8.7 145.8 0.5 0.2 2.5 7.2 4.2 0.1 0.8 3.2 1.5 TNS1 "DKFZp586K0617, MXRA6, PPP1R155, TNS" ENSG00000079308 "Tensin 1" Q9HBL0 2 217799588-218033982 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 173.1;Cardiomyocytes: 339.0;Leydig cells: 169.6;Peritubular cells: 504.0;Sertoli cells: 368.1;Smooth muscle cells: 183.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 135.1;ASC TERT1: 74.1;fHDF/TERT166: 66.6;REH: 75.4;TIME: 63.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018774, HPA036089, HPA036090" Approved Enhanced "Focal adhesion sites" NA NA 47000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Focal adhesion sites" "CAB018774: AB_2207032, HPA036089: AB_10796111, HPA036090: AB_10794322" "unprognostic (4.63e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (2.41e-4)" "unprognostic (4.13e-2)" "unprognostic (5.46e-2)" "unprognostic (2.63e-2)" "unprognostic (1.20e-3)" "unprognostic (7.34e-2)" "unprognostic (2.55e-2)" "unprognostic (1.28e-3)" "unprognostic (5.57e-2)" "unprognostic (9.74e-2)" "unprognostic (4.71e-3)" "unprognostic (5.60e-3)" "unprognostic (2.88e-2)" "unprognostic (7.49e-2)" "prognostic unfavorable (5.19e-4)" 248.2 60.3 51.6 42.9 98.0 42.3 100.9 71.7 45.5 99.5 45.1 373.4 23.4 253.7 44.3 117.8 136.2 80.4 170.4 34.0 53.4 74.6 39.6 117.2 11.5 82.3 79.2 110.4 55.2 33.2 15.4 54.5 106.4 126.1 41.7 7.7 52.9 225.0 171.6 47.8 78.9 178.0 72.2 70.1 115.2 23.5 80.9 21.5 65.8 207.2 7.5 228.4 82.6 82.9 0.3 0.4 8.9 0.1 135.1 74.1 0.8 22.9 7.8 1.3 0.9 10.0 0.1 0.0 13.1 66.6 1.5 1.7 1.4 1.3 0.7 9.4 0.8 19.8 5.7 2.6 9.8 0.1 2.3 35.2 0.0 24.4 0.2 43.6 32.2 0.1 0.6 2.6 18.8 4.4 0.1 1.4 0.9 0.2 0.4 75.4 16.8 1.0 4.8 0.2 2.1 10.1 3.9 9.7 2.0 6.1 3.1 8.5 63.2 16.6 29.5 17.5 4.9 1.1 0.1 0.1 9.8 2.7 1.2 0.0 0.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.4 0.0 0.8 51.6 98.0 71.7 45.5 34.0 53.4 82.3 79.2 106.4 72.2 80.9 82.9 93.3 173.1 85.9 29.7 1.1 16.2 48.6 29.5 42.1 4.8 7.2 21.2 339.0 38.6 27.5 14.7 0.0 8.7 0.5 0.1 7.9 36.1 2.2 3.0 29.5 76.6 0.0 143.1 3.9 19.1 1.5 52.4 1.1 3.8 30.4 8.8 71.7 38.5 13.0 42.1 5.3 0.0 6.1 15.3 19.3 11.9 169.6 16.7 10.6 32.8 1.3 14.1 0.0 15.6 52.0 17.0 0.0 504.0 0.4 12.1 0.0 26.1 22.3 1.3 368.1 29.7 183.5 1.1 1.9 5.7 11.8 1.9 4.1 20.7 0.2 17.3 TNS3 "FLJ13732, H_NH0549I23.2, TEM6, TENS1" ENSG00000136205 "Tensin 3" Q68CZ2 7 47275154-47582558 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 90.8;Oligodendrocyte precursor cells: 150.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 4.0;intermediate monocyte: 3.2;memory B-cell: 2.3;myeloid DC: 2.6;naive B-cell: 1.9;non-classical monocyte: 3.2;plasmacytoid DC: 3.7" "Group enriched" "Detected in many" 7 "B-cells: 2.3;dendritic cells: 3.7;monocytes: 4.0" "Cell line enhanced" "Detected in many" "A549: 266.7;LHCN-M2: 170.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055338, HPA056015" Approved Enhanced "Focal adhesion sites" NA NA 8100 "Cluster 14: Monocytes - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 68: Oligodendrocytes - Mixed function" "Focal adhesion sites" "HPA055338: AB_2682789, HPA056015: AB_2683010" "unprognostic (1.46e-1)" "unprognostic (2.97e-2)" "unprognostic (1.34e-1)" "unprognostic (7.02e-2)" "unprognostic (9.04e-2)" "unprognostic (1.63e-1)" "unprognostic (1.17e-1)" "unprognostic (2.05e-1)" "unprognostic (8.00e-2)" "unprognostic (3.77e-2)" "unprognostic (3.70e-1)" "unprognostic (6.60e-2)" "prognostic favorable (5.21e-4)" "unprognostic (3.13e-2)" "unprognostic (4.41e-2)" "unprognostic (3.20e-2)" "unprognostic (9.09e-3)" 30.4 35.3 57.3 23.8 59.0 6.3 20.9 57.3 51.6 26.2 59.2 19.3 18.7 24.6 6.5 6.4 21.9 21.3 23.8 55.2 64.7 59.7 51.6 40.7 36.7 81.4 63.3 38.3 57.0 30.8 10.5 56.7 73.2 16.3 16.9 9.1 48.5 16.0 22.0 14.4 23.9 16.6 63.2 42.0 30.3 9.4 73.9 8.3 29.8 15.0 19.4 16.2 16.6 63.6 26.5 266.7 15.9 27.7 35.6 28.8 50.6 23.6 133.8 22.7 34.7 60.5 34.7 13.4 40.9 86.4 84.8 49.4 25.9 38.6 20.6 0.2 1.6 37.4 37.3 32.3 36.8 0.1 0.4 28.7 16.3 13.0 20.7 147.3 18.1 0.0 0.1 80.6 170.0 16.4 0.1 0.8 15.4 38.1 31.5 12.1 38.7 44.5 77.5 53.0 1.5 32.3 46.5 9.3 26.9 79.6 35.2 27.6 72.6 35.0 27.1 0.4 36.5 51.7 72.4 30.6 8.7 26.0 129.6 0.2 4.0 0.0 0.0 3.2 0.1 2.3 0.0 0.0 2.6 1.9 0.0 0.0 0.5 0.0 3.2 3.7 0.0 1.4 57.3 59.0 57.3 51.6 55.2 64.7 81.4 63.3 73.2 63.2 73.9 63.6 8.5 67.3 15.8 90.8 10.9 4.8 6.5 26.3 14.2 1.6 8.5 10.3 23.9 35.8 18.8 31.3 0.0 27.7 7.1 41.3 1.9 15.5 11.8 19.8 11.0 12.4 15.0 6.3 2.4 18.4 59.2 14.9 18.3 23.2 0.0 11.4 31.4 40.3 77.4 0.0 6.4 14.0 10.2 41.3 8.4 18.5 6.2 28.9 16.0 76.8 23.1 35.2 1.0 150.8 3.7 23.8 9.9 15.4 5.3 10.5 33.6 14.1 11.1 1.4 26.3 45.5 21.8 2.2 3.0 1.5 3.3 30.0 3.5 20.1 17.0 3.2 TRIM62 "DEAR1, FLJ10759" ENSG00000116525 "Tripartite motif containing 62" Q9BVG3 1 33145399-33182059 "Enzymes, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 21.0" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 50.8;Oligodendrocytes: 26.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "AF22: 23.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050061 Approved "Vesicles,Focal adhesion sites" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 68: Oligodendrocytes - Mixed function" "Vesicles, Focal adhesion sites" "HPA050061: AB_2681001" "unprognostic (1.57e-1)" "unprognostic (4.39e-2)" "unprognostic (2.39e-2)" "unprognostic (2.62e-2)" "unprognostic (1.14e-2)" "unprognostic (5.80e-2)" "unprognostic (5.10e-5)" "unprognostic (2.05e-2)" "unprognostic (1.14e-1)" "unprognostic (4.32e-2)" "unprognostic (3.55e-3)" "unprognostic (3.66e-1)" "prognostic unfavorable (7.08e-5)" "unprognostic (2.14e-1)" "unprognostic (1.10e-1)" "unprognostic (1.05e-1)" "unprognostic (2.05e-3)" 3.1 6.6 8.7 2.9 13.1 4.8 3.6 10.0 11.9 3.2 2.3 3.2 2.4 3.1 2.6 5.1 3.0 2.0 3.5 8.5 10.4 3.5 1.8 3.1 4.6 10.7 11.3 3.7 3.1 2.9 6.4 3.4 12.1 5.1 2.1 2.1 5.2 2.9 4.9 12.5 4.2 2.8 7.4 5.1 4.3 2.3 12.4 5.2 3.9 2.5 4.5 4.8 4.4 21.0 3.7 2.7 23.9 3.9 5.7 2.5 7.6 3.4 9.9 6.3 5.5 3.0 3.7 5.9 3.8 3.0 3.2 7.2 5.0 4.3 5.6 5.8 3.8 6.5 3.2 2.5 5.7 2.2 16.2 5.2 3.9 8.7 2.0 9.9 6.3 5.0 1.1 3.8 6.1 9.9 6.8 2.0 6.0 4.3 3.5 8.6 12.8 2.7 3.8 9.6 6.0 3.7 3.8 14.5 16.8 12.6 4.1 1.4 6.3 2.7 3.8 8.1 2.8 6.9 3.3 2.7 5.1 3.9 3.5 1.2 1.0 3.4 1.3 1.8 2.3 1.1 1.9 1.8 0.9 1.4 1.3 1.2 2.3 1.0 1.1 0.4 4.7 1.1 8.7 13.1 10.0 11.9 8.5 10.4 10.7 11.3 12.1 7.4 12.4 21.0 2.0 3.2 2.2 2.6 1.8 2.7 0.8 1.7 2.8 3.4 3.5 1.9 0.9 0.0 1.2 1.8 0.0 1.1 2.5 1.5 0.0 1.4 0.5 0.6 1.1 1.4 1.8 0.4 1.9 1.9 1.8 2.1 4.1 1.3 1.3 1.7 1.1 0.7 1.2 10.1 10.2 1.5 4.1 1.2 1.6 0.5 2.5 1.3 0.0 10.3 1.4 1.5 3.1 50.8 26.0 2.6 0.6 4.9 2.6 2.1 1.2 1.0 0.4 1.0 6.6 2.0 2.1 1.3 0.6 2.8 4.7 1.4 3.0 3.4 0.9 2.0 TRIM71 "LIN-41, LIN41" ENSG00000206557 "Tripartite motif containing 71" Q2Q1W2 3 32817997-32897824 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "RNA-mediated gene silencing, Ubl conjugation pathway" "Developmental protein, RNA-binding, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 4.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Extravillous trophoblasts: 15.6;Inhibitory neurons: 4.5;Oligodendrocyte precursor cells: 4.5;Spermatogonia: 13.7" "Cancer enriched" "Detected in some" 28 "testis cancer: 28.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 31.4;BEWO: 94.5;Hep G2: 63.8;NTERA-2: 84.3;SuSa: 76.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA038141, HPA038142" Uncertain Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 5: NTERA-2 - Transcription" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Actin filaments, Focal adhesion sites" "HPA038141: AB_2675857, HPA038142: AB_10697240" "unprognostic (2.93e-2)" "unprognostic (4.29e-3)" "unprognostic (1.70e-1)" "unprognostic (1.02e-2)" "unprognostic (2.58e-2)" "unprognostic (3.27e-2)" "unprognostic (2.09e-2)" "unprognostic (1.25e-1)" "unprognostic (3.16e-2)" "unprognostic (3.04e-1)" "unprognostic (1.11e-2)" "unprognostic (3.11e-1)" "unprognostic (4.36e-6)" "unprognostic (3.92e-2)" "unprognostic (9.27e-2)" "unprognostic (8.17e-2)" "unprognostic (4.65e-2)" 0.0 0.0 1.0 0.0 1.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.8 0.9 0.0 0.7 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 31.4 0.0 0.0 0.0 94.5 0.0 0.0 0.0 0.0 23.1 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 1.6 0.0 63.8 0.0 1.8 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.3 0.4 0.0 0.0 0.6 6.9 84.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 76.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 0.8 0.9 0.8 0.1 0.1 0.1 0.0 0.8 0.2 0.0 9.6 4.1 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.1 0.0 2.7 0.0 1.8 0.0 0.0 3.9 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.2 0.0 0.0 3.1 0.0 15.6 0.3 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 4.5 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 1.0 0.1 0.0 0.0 4.5 0.1 0.0 0.0 0.4 0.0 0.0 0.0 3.6 0.7 0.5 0.0 0.0 0.1 0.3 13.7 0.0 0.0 4.0 0.1 0.0 0.0 0.0 TRIP6 "MGC10556, MGC10558, MGC29959, MGC3837, MGC4423, OIP1, ZRP-1" ENSG00000087077 "Thyroid hormone receptor interactor 6" Q15654 7 100867387-100873454 "Predicted intracellular proteins" "Cell adhesion, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046454, CAB046460, HPA052813" Approved Supported "Plasma membrane,Focal adhesion sites,Cytosol" NA NA 21000 "Cluster 26: Non-specific - Mitochondria" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Focal adhesion sites, Cytosol" "CAB046454: AB_10604048, CAB046460: AB_2303907, HPA052813: AB_2681961" "unprognostic (7.94e-3)" "unprognostic (1.06e-1)" "unprognostic (3.22e-3)" "unprognostic (2.84e-3)" "unprognostic (3.52e-2)" "unprognostic (2.92e-2)" "unprognostic (3.18e-2)" "unprognostic (4.61e-3)" "unprognostic (8.48e-2)" "unprognostic (4.18e-2)" "unprognostic (5.08e-2)" "unprognostic (1.42e-1)" "unprognostic (1.25e-2)" "unprognostic (5.07e-2)" "unprognostic (9.71e-2)" "unprognostic (1.92e-1)" "unprognostic (1.25e-1)" 42.2 43.0 34.3 15.7 39.5 15.7 42.6 36.2 41.6 59.4 40.4 45.2 9.7 74.6 16.2 63.7 49.5 37.0 39.1 32.6 36.2 55.8 41.1 33.8 14.6 40.6 36.9 50.6 39.8 46.4 16.8 27.4 35.9 42.9 8.4 5.4 46.8 56.7 10.2 55.1 21.5 27.5 36.9 20.0 27.6 18.4 38.4 16.6 50.5 5.8 12.1 47.2 52.5 37.0 128.1 63.4 26.8 126.1 37.8 44.9 131.2 82.3 79.8 101.2 94.8 55.8 143.9 5.5 81.3 87.7 128.3 94.2 38.0 149.2 27.3 19.1 58.5 0.5 117.9 0.8 99.3 66.5 7.1 81.1 94.0 67.8 108.2 64.2 52.8 19.1 83.3 1.0 90.5 286.9 1.3 99.5 92.4 52.3 50.4 47.9 27.0 12.7 65.5 42.8 9.7 1.7 67.5 192.3 78.1 43.8 20.3 77.5 86.5 149.5 145.8 167.5 186.7 1.0 2.1 0.8 92.9 7.8 230.5 0.0 1.2 0.2 0.1 2.1 0.4 2.5 0.9 0.7 1.9 2.4 1.1 0.6 0.0 0.0 3.8 5.2 0.9 0.4 34.3 39.5 36.2 41.6 32.6 36.2 40.6 36.9 35.9 36.9 38.4 37.0 24.5 48.1 38.8 14.4 8.0 131.9 151.5 144.1 78.0 0.9 48.3 55.8 13.9 38.6 87.0 60.7 0.0 113.0 12.0 9.5 80.3 106.9 1.1 22.7 46.1 26.3 4.9 6.7 0.3 84.3 90.4 54.6 40.8 44.8 8.2 55.3 23.9 28.8 44.0 1.7 0.4 12.8 34.6 8.0 59.3 2.8 65.9 17.5 37.4 5.6 20.3 94.8 0.0 4.0 6.5 95.0 13.1 72.6 16.0 72.9 3.6 130.0 34.3 4.6 72.3 50.9 104.0 4.7 4.5 68.2 98.3 132.8 7.1 58.3 18.8 155.6 USP40 FLJ10785 ENSG00000085982 "Ubiquitin specific peptidase 40" Q9NVE5 2 233475520-233566782 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 79.3;Oligodendrocytes: 127.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005821 Uncertain Approved "Vesicles,Focal adhesion sites" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 68: Epididymis - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "Focal adhesion sites" "HPA005821: AB_1080526" "unprognostic (2.19e-1)" "unprognostic (1.04e-1)" "unprognostic (1.13e-1)" "unprognostic (1.33e-1)" "unprognostic (3.70e-1)" "unprognostic (2.15e-1)" "unprognostic (5.30e-2)" "unprognostic (2.25e-1)" "unprognostic (1.80e-2)" "unprognostic (1.18e-1)" "unprognostic (1.96e-1)" "unprognostic (1.26e-1)" "unprognostic (2.22e-1)" "unprognostic (1.45e-1)" "unprognostic (4.09e-2)" "unprognostic (1.90e-2)" "unprognostic (2.53e-2)" 11.8 12.0 10.4 7.5 17.0 3.4 13.9 12.8 11.4 10.0 16.5 9.4 10.5 10.6 24.0 10.4 11.5 11.6 8.2 10.2 12.0 14.2 13.2 12.5 7.2 19.4 14.2 15.9 14.0 16.8 8.5 12.4 19.0 13.5 9.5 14.2 12.9 10.4 9.6 19.7 10.1 8.5 12.3 9.9 13.1 14.7 16.2 10.1 16.4 7.6 7.8 9.6 7.5 25.4 17.3 19.9 17.6 12.0 25.2 23.0 15.7 16.4 12.4 14.7 16.0 14.3 20.2 0.4 4.7 26.4 38.6 30.3 13.3 29.7 20.6 0.0 9.0 13.3 17.4 24.3 22.3 5.8 8.9 22.2 21.1 22.2 30.9 26.2 17.3 8.1 22.0 3.2 21.4 14.0 6.2 8.5 7.9 17.8 16.0 0.0 36.3 8.1 17.9 27.6 9.6 10.3 13.5 13.5 16.9 12.9 15.4 12.9 17.3 20.9 13.1 8.9 20.6 6.0 4.9 0.8 27.1 10.2 18.6 0.0 1.0 0.0 0.5 1.1 0.2 0.4 0.5 0.4 1.5 0.7 0.7 0.7 0.1 0.5 0.9 1.9 0.8 0.5 10.4 17.0 12.8 11.4 10.2 12.0 19.4 14.2 19.0 12.3 16.2 25.4 11.8 32.1 35.5 79.3 7.9 7.4 9.1 13.6 15.4 18.1 17.0 14.7 10.7 10.0 19.9 16.5 25.0 21.2 6.7 9.9 7.9 9.4 8.4 19.8 18.3 11.1 15.0 5.7 25.9 12.6 10.6 11.9 21.4 21.3 9.5 23.4 12.8 25.4 8.2 23.5 38.2 10.9 4.1 11.6 3.6 10.7 6.8 9.1 3.6 40.3 5.9 11.9 4.1 48.2 127.7 10.5 12.6 8.2 10.9 12.9 13.9 14.6 21.0 19.4 13.1 17.5 10.6 30.2 20.9 17.2 10.5 15.7 5.5 21.1 12.1 10.0 VASP ENSG00000125753 "Vasodilator stimulated phosphoprotein" P50552 19 45506579-45526983 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 443.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 52.7" "Group enriched" "Detected in all" 7 "granulocytes: 52.7;monocytes: 22.7" "Cell line enhanced" "Detected in all" "HMC-1: 270.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004612, HPA005724" Enhanced Supported "Plasma membrane,Cell Junctions,Focal adhesion sites" NA NA 32000000 "Cluster 52: Eosinophils - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 15: RT4 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Cell Junctions, Focal adhesion sites" "CAB004612: AB_2213431, HPA005724: AB_1858721" "unprognostic (3.07e-2)" "unprognostic (1.07e-2)" "unprognostic (4.70e-2)" "unprognostic (7.85e-3)" "unprognostic (8.31e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (3.49e-5)" "unprognostic (1.66e-3)" "unprognostic (1.58e-1)" "unprognostic (1.30e-2)" "unprognostic (3.64e-3)" "unprognostic (4.39e-1)" "prognostic unfavorable (5.91e-7)" "unprognostic (1.15e-1)" "unprognostic (1.15e-1)" "unprognostic (1.69e-1)" "unprognostic (1.08e-2)" 54.5 24.6 9.3 75.2 8.3 94.0 42.5 9.2 12.6 37.7 11.0 88.9 61.9 89.1 6.0 37.5 54.4 27.0 36.4 8.1 9.4 39.1 27.3 58.2 48.7 13.0 10.9 22.5 20.6 10.7 17.1 31.5 13.8 43.8 20.4 1.9 30.7 39.1 12.5 32.8 63.6 36.5 11.7 107.0 70.5 14.7 15.0 24.9 27.6 8.5 32.0 71.6 39.0 12.0 68.9 66.3 20.6 35.6 10.2 17.4 50.5 70.2 52.8 47.4 40.9 30.1 142.0 31.2 55.7 56.4 31.3 60.6 6.2 69.5 15.9 87.0 14.8 183.7 32.3 55.4 56.6 68.1 270.1 26.8 38.2 44.5 28.5 38.3 71.1 25.8 112.1 67.5 29.4 53.7 30.3 58.7 36.0 65.1 44.5 21.6 12.6 12.2 40.9 216.2 23.0 16.3 83.6 41.7 48.2 13.0 45.7 115.2 107.0 74.7 74.4 24.7 112.4 32.8 43.3 54.7 52.4 82.3 92.3 13.3 8.5 52.7 4.1 13.9 2.8 3.4 3.3 3.9 5.5 3.3 2.1 2.5 34.5 4.0 22.7 2.1 2.6 5.8 9.3 8.3 9.2 12.6 8.1 9.4 13.0 10.9 13.8 11.7 15.0 12.0 80.9 16.0 19.5 2.9 99.4 98.3 95.6 48.8 37.0 6.9 53.5 57.0 19.0 48.6 41.5 33.1 27.1 67.1 85.9 202.3 17.6 138.6 3.2 33.9 30.5 77.0 114.7 20.0 2.6 98.2 443.6 26.7 81.6 58.1 83.1 17.4 48.5 15.8 160.1 6.7 3.4 159.3 44.7 132.5 232.0 3.8 26.1 192.9 49.8 10.3 162.9 13.2 185.3 2.0 2.3 212.5 245.5 49.2 38.2 73.4 134.6 20.4 18.6 14.7 131.5 46.5 89.4 18.9 15.5 38.7 77.7 140.9 95.7 21.0 129.5 144.8 VCL ENSG00000035403 Vinculin P18206 10 73995193-74121363 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" Actin-binding "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 339.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+: 568.3;hTERT-RPE1: 547.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002131, CAB002453, HPA063777" Enhanced Enhanced "Focal adhesion sites" NA NA 750000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" "Focal adhesion sites" "CAB002453: AB_564057, HPA002131: AB_1080570, HPA063777: AB_2685121" "unprognostic (8.49e-2)" "unprognostic (1.61e-2)" "unprognostic (3.14e-1)" "unprognostic (6.31e-2)" "unprognostic (3.34e-1)" "unprognostic (9.62e-3)" "unprognostic (2.72e-3)" "unprognostic (2.67e-3)" "unprognostic (3.42e-2)" "unprognostic (1.46e-1)" "prognostic unfavorable (2.75e-4)" "unprognostic (1.29e-1)" "unprognostic (3.68e-2)" "unprognostic (4.03e-2)" "unprognostic (4.02e-2)" "unprognostic (1.89e-1)" "unprognostic (1.37e-3)" 85.8 19.1 9.9 52.2 10.6 41.5 45.3 8.4 11.3 73.9 33.4 180.3 35.3 167.6 45.9 92.2 75.9 69.4 132.2 10.5 11.3 37.2 24.1 68.7 18.7 10.3 10.3 45.2 40.3 51.3 13.8 88.6 13.3 131.7 73.1 12.5 31.6 151.9 136.9 37.9 52.7 224.7 9.9 41.9 63.5 41.3 12.1 12.8 39.6 144.1 23.9 135.7 56.3 8.4 147.2 97.0 174.2 123.8 213.2 246.2 95.8 188.5 568.3 126.3 141.9 88.4 124.0 6.5 153.1 331.6 86.3 183.3 115.7 95.0 132.5 12.3 49.6 69.4 92.2 37.2 116.5 14.1 101.8 205.0 25.0 171.5 154.8 547.4 171.0 11.6 50.7 14.3 213.1 25.2 2.0 16.6 82.8 69.9 342.4 24.0 90.9 18.6 180.4 185.8 6.5 25.8 104.7 117.2 53.9 152.8 54.5 21.2 230.9 136.9 57.0 67.0 179.4 2.6 6.0 28.4 160.0 38.9 39.7 15.0 13.6 36.2 14.9 17.1 10.4 5.6 7.1 7.8 20.7 2.3 2.6 5.3 11.2 4.4 19.0 8.0 1.9 28.3 9.9 10.6 8.4 11.3 10.5 11.3 10.3 10.3 13.3 9.9 12.1 8.4 68.0 99.3 39.7 56.5 13.4 114.7 161.4 68.4 30.7 13.4 39.4 58.5 339.5 37.1 79.8 42.3 85.5 51.5 46.7 91.2 3.9 60.8 5.0 98.2 152.6 60.4 38.3 5.9 63.2 61.6 78.6 74.4 66.3 149.1 35.4 45.5 56.7 34.4 23.6 16.8 47.5 44.5 22.4 31.9 51.0 7.5 50.1 77.9 26.6 55.3 44.7 9.7 61.8 18.6 4.6 125.5 48.3 76.8 8.0 100.1 13.7 14.8 37.7 34.5 105.2 49.6 179.9 18.6 13.7 45.6 93.1 39.7 18.3 44.5 48.7 94.8 VIPR2 "VPAC2, VPAC2R" ENSG00000106018 "Vasoactive intestinal peptide receptor 2" P41587 7 159028175-159144867 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "dendritic cells: 20.6;Excitatory neurons: 15.2;Muller glia cells: 38.9;Oligodendrocyte precursor cells: 49.8;Rod photoreceptor cells: 45.1" "Cancer enhanced" "Detected in some" "glioma: 2.8" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 17 "plasmacytoid DC: 12.3" "Lineage enriched" "Detected in single" 17 "dendritic cells: 12.3" "Cell line enhanced" "Detected in some" "HeLa: 6.6;HMC-1: 9.0;MOLT-4: 12.9;U-266/70: 40.5" "Region enhanced" "Detected in many" "olfactory bulb: 27.1" "Low region specificity" "Detected in many" HPA062707 Approved Approved "Focal adhesion sites" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 46: Fibroblasts - ECM organization" "Cluster 29: U-266 - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Focal adhesion sites" "HPA062707: AB_2684842" "unprognostic (3.65e-2)" "unprognostic (2.13e-2)" "unprognostic (4.26e-2)" "unprognostic (2.04e-2)" "unprognostic (6.31e-2)" "unprognostic (4.10e-2)" "unprognostic (1.03e-1)" "unprognostic (8.58e-2)" "unprognostic (2.32e-2)" "unprognostic (1.02e-1)" "unprognostic (9.60e-2)" "unprognostic (1.74e-1)" "unprognostic (1.88e-1)" "unprognostic (2.49e-2)" "unprognostic (1.26e-1)" "unprognostic (1.21e-1)" "unprognostic (8.89e-2)" 12.5 0.8 2.2 0.9 1.6 0.4 2.5 0.6 6.9 16.8 1.4 13.8 1.7 6.8 12.2 1.4 4.5 2.5 16.4 2.1 2.0 1.1 0.4 0.6 1.1 2.2 0.8 12.0 17.5 0.9 2.7 5.7 2.6 9.2 1.1 6.5 0.3 20.5 7.4 0.7 4.8 4.2 2.1 0.8 8.6 2.2 1.3 8.2 0.2 5.4 0.4 6.8 11.2 2.9 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.1 0.0 0.2 12.9 0.1 1.0 0.0 0.0 3.2 0.1 0.7 0.0 0.0 2.8 2.3 0.1 0.2 0.0 0.3 0.0 0.7 0.0 0.0 0.4 0.0 0.0 40.5 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.1 0.0 0.0 12.3 0.0 0.1 2.2 1.6 0.6 6.9 2.1 2.0 2.2 0.8 2.6 2.1 1.3 2.9 0.8 0.0 0.0 2.9 0.7 0.6 2.9 0.0 1.8 1.7 1.6 1.8 7.5 0.0 0.0 0.0 2.1 0.0 20.6 0.0 0.0 0.0 1.3 0.4 6.9 0.4 0.0 0.0 15.2 6.7 0.0 10.8 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 4.1 0.0 0.0 0.0 0.3 1.9 10.2 0.5 1.8 1.9 0.0 38.9 4.1 49.8 0.3 0.8 0.0 2.6 2.4 2.0 0.0 0.5 0.0 45.1 0.0 2.9 5.6 3.6 10.2 0.1 0.0 0.0 3.8 0.1 0.0 0.3 VTCN1 "B7-H4, B7H4, B7S1, B7x, FLJ22418" ENSG00000134258 "V-set domain containing T cell activation inhibitor 1" Q7Z7D3 1 117143587-117210960 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 100.9;fallopian tube: 32.7;pancreas: 30.1" "Cell type enhanced" "Detected in some" "Breast glandular cells: 62.3;Collecting duct cells: 55.2;Ductal cells: 83.6;Endometrial ciliated cells: 42.7;Exocrine glandular cells: 34.2;Glandular and luminal cells: 79.1" "Group enriched" "Detected in many" 6 "breast cancer: 55.8;endometrial cancer: 45.2;ovarian cancer: 49.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SK-BR-3: 244.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA054200 Approved Approved "Plasma membrane,Cell Junctions,Focal adhesion sites" No NA "Cluster 5: Breast - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "Cell Junctions, Focal adhesion sites" "HPA054200: AB_2682415" "unprognostic (4.13e-1)" "unprognostic (1.71e-3)" "unprognostic (2.95e-1)" "unprognostic (3.44e-2)" "unprognostic (1.71e-3)" "unprognostic (2.56e-1)" "unprognostic (7.94e-2)" "unprognostic (4.86e-2)" "unprognostic (3.53e-1)" "unprognostic (1.17e-2)" "unprognostic (4.54e-2)" "unprognostic (5.47e-2)" "unprognostic (1.50e-2)" "unprognostic (1.06e-1)" "unprognostic (2.42e-1)" "unprognostic (3.07e-1)" "unprognostic (1.45e-2)" 0.1 0.0 0.0 0.0 0.0 0.0 100.9 0.0 0.0 15.3 0.0 0.0 0.4 4.5 5.0 0.4 32.7 5.0 0.2 0.0 0.0 17.3 1.1 0.7 0.0 0.0 0.0 0.1 30.1 0.0 0.1 0.8 0.0 3.0 0.0 0.0 22.1 7.8 0.2 2.8 0.0 0.1 0.0 0.0 3.6 1.1 0.1 0.1 0.0 0.0 0.0 3.2 0.1 0.0 1.0 0.1 1.7 0.0 0.0 0.0 44.8 0.0 0.0 0.0 0.0 0.0 0.9 0.0 7.5 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.9 0.1 0.0 0.1 0.0 0.1 0.1 0.2 0.1 4.2 0.1 1.2 0.0 0.0 244.8 0.1 29.9 14.2 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.4 0.0 2.5 6.9 0.0 0.0 62.3 18.4 1.1 0.0 22.6 55.2 0.0 3.4 1.1 0.0 0.0 83.6 2.5 42.7 4.4 0.6 0.0 0.0 0.8 34.2 1.4 0.4 0.0 79.1 0.0 0.0 0.0 0.0 0.6 0.0 0.6 0.0 6.1 0.0 0.0 1.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.3 11.3 0.0 0.0 0.0 1.6 0.0 0.3 8.3 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 3.0 0.5 0.0 0.0 4.8 ZBTB8A "BOZF1, FLJ90065, ZBTB8, ZNF916A" ENSG00000160062 "Zinc finger and BTB domain containing 8A" Q96BR9 1 32539427-32605941 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 1.5" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031768, HPA031769, HPA031770" Approved Approved "Nuclear speckles,Focal adhesion sites" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 36: Stromal cells - Cell proliferation" "Nuclear speckles, Focal adhesion sites" "HPA031768: AB_10610568, HPA031769: AB_2674036, HPA031770: AB_2674037" "unprognostic (1.71e-1)" "unprognostic (1.98e-1)" "unprognostic (1.01e-1)" "unprognostic (7.40e-2)" "unprognostic (7.21e-2)" "unprognostic (2.85e-2)" "unprognostic (9.45e-5)" "unprognostic (1.62e-2)" "unprognostic (2.04e-1)" "unprognostic (7.83e-3)" "unprognostic (4.23e-3)" "unprognostic (1.78e-1)" "unprognostic (8.10e-2)" "unprognostic (2.88e-2)" "unprognostic (1.61e-1)" "unprognostic (1.47e-1)" "unprognostic (3.15e-2)" 3.8 2.2 1.5 1.6 1.6 1.2 3.4 3.5 1.6 6.2 1.1 2.9 1.8 6.1 3.2 3.4 3.3 2.7 2.4 1.3 0.9 2.4 2.0 2.8 0.9 1.5 1.2 3.4 2.6 3.6 1.8 2.7 1.5 3.0 3.0 1.5 2.5 4.0 2.8 1.8 2.0 5.1 0.8 1.3 3.1 2.4 1.2 1.3 5.5 6.1 1.5 3.7 3.0 2.5 6.4 1.8 7.2 7.8 5.0 6.7 5.4 6.2 4.9 5.7 5.8 0.8 5.0 5.3 4.2 6.7 2.5 4.9 7.2 5.0 5.0 1.4 4.8 0.2 5.7 2.7 6.5 1.2 0.3 4.5 7.0 4.2 11.0 5.7 6.5 4.5 1.0 3.6 5.8 6.5 3.5 0.6 6.5 3.1 2.5 6.3 10.4 4.1 3.5 6.4 6.0 5.5 8.8 4.3 8.4 3.8 5.7 2.9 6.8 7.6 6.2 10.5 4.6 6.5 3.3 3.9 5.2 1.3 3.2 1.5 0.2 0.2 0.2 0.1 0.2 0.2 0.1 0.2 0.2 0.3 0.1 0.2 1.0 0.7 0.2 0.5 0.1 0.1 1.5 1.6 3.5 1.6 1.3 0.9 1.5 1.2 1.5 0.8 1.2 2.5 17.0 16.0 13.8 5.9 1.4 4.1 7.8 8.0 5.2 11.7 7.4 5.8 4.1 4.3 5.8 7.3 22.9 3.5 3.8 6.5 1.9 6.9 5.9 7.5 30.0 20.1 4.9 6.1 9.4 5.1 6.7 14.5 9.7 11.8 2.5 11.2 30.4 5.2 1.6 6.7 7.8 5.4 2.0 4.1 7.4 7.2 19.9 2.3 3.6 15.9 1.8 4.0 0.0 21.6 20.6 6.0 4.7 35.3 3.2 10.7 3.3 3.0 3.6 10.8 32.9 23.3 12.9 2.0 6.4 3.8 3.8 1.5 2.3 4.1 8.8 6.4 ZNF185 SCELL ENSG00000147394 "Zinc finger protein 185 with LIM domain" O15231 X 152914442-152973480 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 328.7;esophagus: 326.7" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 32.2;Pancreatic endocrine cells: 72.0;Squamous epithelial cells: 69.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 51.8" "Group enriched" "Detected in many" 5 "granulocytes: 51.8;monocytes: 27.4" "Cell line enhanced" "Detected in many" "A-431: 124.4;EFO-21: 139.9;HBEC3-KT: 100.0;PC-3: 87.7;TIME: 236.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000400, HPA016438" Enhanced Supported "Plasma membrane,Actin filaments,Focal adhesion sites,Cytosol" NA NA 220000 "Cluster 18: Basophils - Vesicular transport" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "Actin filaments, Focal adhesion sites" "HPA000400: AB_1080685, HPA016438: AB_1859109" "unprognostic (1.34e-1)" "unprognostic (1.39e-1)" "unprognostic (1.84e-1)" "unprognostic (2.43e-2)" "unprognostic (9.75e-3)" "unprognostic (2.69e-1)" "unprognostic (2.49e-2)" "prognostic unfavorable (1.50e-4)" "unprognostic (7.94e-2)" "unprognostic (6.28e-2)" "prognostic unfavorable (3.30e-5)" "unprognostic (5.18e-2)" "unprognostic (8.12e-2)" "unprognostic (1.99e-1)" "unprognostic (1.37e-1)" "unprognostic (2.10e-1)" "unprognostic (1.60e-1)" 5.2 11.6 4.0 5.6 4.2 8.7 12.2 4.8 3.7 69.5 10.9 4.5 1.8 21.8 328.7 326.7 16.4 6.7 1.8 3.2 3.9 11.0 2.1 12.1 4.5 3.5 3.8 6.1 4.3 3.7 8.4 24.9 3.5 24.5 4.2 3.4 44.8 144.1 2.9 53.7 2.6 10.3 4.2 4.5 7.4 3.4 4.3 3.6 21.3 2.9 41.0 11.6 117.5 3.9 124.4 25.9 2.4 1.6 3.0 4.0 5.5 6.0 0.4 14.8 2.2 0.9 36.7 1.6 139.9 9.0 1.4 17.3 3.7 100.0 60.1 1.5 2.4 7.9 9.8 4.1 7.0 0.5 0.6 2.9 70.2 1.6 57.0 14.6 76.5 1.6 0.5 1.1 0.4 29.1 0.5 0.7 1.9 31.4 87.7 0.5 0.4 0.9 7.7 11.5 1.0 8.2 0.2 22.7 3.6 23.3 23.3 2.7 236.2 0.8 50.5 3.0 4.5 1.2 1.0 1.1 1.6 8.9 1.7 51.8 27.4 11.4 1.0 24.4 0.6 0.7 0.7 1.2 7.4 0.6 1.1 0.7 18.5 0.5 21.1 4.9 1.0 20.7 4.0 4.2 4.8 3.7 3.2 3.9 3.5 3.8 3.5 4.2 4.3 3.9 1.1 12.8 2.6 1.3 0.7 9.2 6.2 5.7 4.6 0.5 5.7 7.6 0.9 1.5 9.4 9.2 2.1 3.8 1.7 1.0 0.0 8.6 0.6 14.1 4.2 1.1 0.0 0.0 1.0 3.0 5.0 2.2 2.6 32.2 1.3 3.9 1.4 0.1 9.4 0.0 1.7 2.5 2.0 11.3 4.0 0.3 1.2 9.5 3.6 0.0 14.4 4.0 0.0 1.0 1.4 72.0 0.3 1.2 0.1 7.6 0.3 1.2 6.9 0.3 0.0 0.5 1.9 4.2 5.8 69.7 21.2 0.7 0.8 0.4 2.4 21.3 ZYX ENSG00000159840 Zyxin Q15942 7 143381295-143391111 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 596.6" "Cell type enhanced" "Detected in many" "Macrophages: 207.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 163.3" "Group enriched" "Detected in all" 4 "dendritic cells: 58.4;granulocytes: 163.3;monocytes: 83.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004835, CAB009321, HPA073497, CAB075747" Enhanced Supported "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA 180000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 51: Myeloid cells - Hemostasis" "Focal adhesion sites" "Plasma membrane, Actin filaments" "CAB009321: AB_2221290, CAB075747: AB_2665753, HPA004835: AB_1080771, HPA073497: AB_2686611" "unprognostic (1.96e-2)" "unprognostic (5.35e-2)" "unprognostic (2.36e-2)" "unprognostic (1.25e-1)" "unprognostic (1.44e-2)" "unprognostic (1.18e-1)" "unprognostic (2.21e-3)" "unprognostic (1.66e-3)" "unprognostic (2.60e-1)" "unprognostic (4.22e-1)" "unprognostic (1.98e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (7.92e-5)" "unprognostic (1.39e-1)" "unprognostic (8.12e-2)" "unprognostic (1.95e-1)" "unprognostic (6.72e-2)" 211.5 75.4 21.6 82.5 24.3 106.3 191.0 24.4 33.5 275.7 24.8 382.6 28.1 596.6 16.5 136.7 294.9 57.0 152.0 21.9 21.9 99.4 89.9 316.8 53.9 27.5 24.7 168.7 78.5 84.3 52.4 38.4 27.5 171.9 20.2 5.2 108.1 75.3 113.3 130.7 148.7 127.7 23.8 213.6 154.0 98.9 28.8 27.6 89.0 19.1 31.1 301.6 185.9 26.8 73.9 39.3 50.6 70.5 93.9 208.2 63.4 152.1 158.9 146.5 122.7 135.4 42.6 4.6 57.5 168.5 84.1 55.8 31.7 138.0 67.8 81.6 18.7 105.9 45.7 46.9 163.8 86.4 162.6 222.9 60.5 160.1 54.0 90.5 187.9 9.1 28.0 42.8 159.6 73.4 1.3 165.9 110.0 25.4 273.1 16.3 28.0 6.4 112.2 34.6 2.8 39.5 112.3 99.2 57.0 45.9 12.1 80.5 343.7 176.5 74.1 187.9 152.4 15.6 20.4 11.7 154.6 87.4 119.8 18.9 70.8 48.2 20.2 70.4 16.2 3.1 19.4 23.3 58.4 2.0 11.7 13.8 163.3 14.7 83.6 14.5 19.1 44.1 21.6 24.3 24.4 33.5 21.9 21.9 27.5 24.7 27.5 23.8 28.8 26.8 51.6 6.4 6.4 8.1 26.7 33.8 174.0 78.4 26.7 3.7 40.2 85.3 11.6 25.8 45.4 35.0 0.0 40.6 51.7 40.1 7.9 100.3 1.5 23.4 172.6 58.2 38.2 19.3 36.9 94.1 95.8 66.6 44.9 42.0 36.8 13.7 55.3 32.0 164.6 0.0 18.3 26.7 24.4 195.7 95.1 6.8 28.6 207.1 14.2 7.5 171.9 15.1 40.2 7.5 5.2 169.8 48.2 55.3 20.3 61.3 19.8 19.6 9.9 3.0 85.5 48.7 103.9 7.3 9.9 46.3 20.2 28.0 91.9 8.8 28.6 106.4