Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ADCY5 AC5 ENSG00000173175 "Adenylate cyclase 5" O95622 3 123282296-123449090 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 97.7;heart muscle: 105.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 75.5;Inhibitory neurons: 44.0;Oligodendrocytes: 89.7;Paneth cells: 59.6;Peritubular cells: 73.7;Sertoli cells: 65.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 15.5;RPMI-8226: 2.7;RPTEC TERT1: 5.2" "Region enriched" "Detected in all" 5 "basal ganglia: 388.0" "Region enriched" "Detected in all" 6 "basal ganglia: 155.9" "HPA017730, HPA077682" Uncertain Enhanced "Intermediate filaments" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 54: Cardiomyocytes - Muscle contraction" "Intermediate filaments" "HPA017730: AB_1844595, HPA077682: AB_2686851" "unprognostic (3.55e-2)" "unprognostic (1.01e-3)" "unprognostic (7.61e-3)" "unprognostic (2.05e-2)" "unprognostic (1.25e-1)" "unprognostic (1.26e-2)" "unprognostic (1.48e-1)" "unprognostic (7.61e-2)" "unprognostic (2.49e-2)" "unprognostic (2.34e-1)" "unprognostic (7.27e-3)" "unprognostic (2.64e-2)" "prognostic favorable (7.46e-6)" "unprognostic (1.81e-2)" "unprognostic (5.65e-2)" "unprognostic (3.19e-2)" "unprognostic (5.97e-4)" 18.9 3.3 25.5 4.9 97.7 0.0 10.6 13.9 43.9 9.8 0.0 35.1 5.2 14.7 5.7 18.8 12.7 10.0 105.2 25.8 15.9 12.8 3.3 4.1 2.3 20.5 18.3 13.2 7.5 0.8 14.3 6.1 17.4 19.8 5.6 4.5 4.0 21.5 2.7 2.6 13.0 18.2 10.8 6.5 21.2 8.2 34.4 1.3 1.9 5.8 3.0 23.2 7.8 30.1 0.0 0.6 1.3 0.1 0.1 0.1 0.3 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.3 0.2 2.3 0.5 0.6 0.0 0.0 0.1 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 15.5 0.0 0.0 0.8 0.0 0.1 0.0 0.3 2.7 5.2 0.5 1.8 1.6 0.0 0.5 0.1 1.7 0.0 0.1 0.0 0.1 1.2 0.1 0.2 0.1 0.6 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.5 97.7 13.9 43.9 25.8 15.9 20.5 18.3 17.4 10.8 34.4 30.1 0.3 0.0 0.0 8.1 0.1 0.3 0.1 0.2 0.0 21.8 0.4 5.8 75.5 8.6 0.0 7.3 0.0 1.4 0.0 2.6 0.0 15.9 0.9 1.5 7.1 1.8 0.0 0.0 34.0 6.9 4.0 5.2 0.0 4.0 0.0 4.6 3.9 0.1 0.3 0.0 44.0 0.3 0.0 0.0 0.3 3.0 20.5 0.1 0.0 6.5 1.0 1.0 0.0 19.1 89.7 0.4 59.6 73.7 0.0 0.1 0.3 0.8 0.0 2.2 65.7 0.6 21.4 0.8 6.3 0.2 0.9 12.4 0.2 1.0 2.0 0.1 CCT8 "C21orf112, Cctq, PRED71" ENSG00000156261 "Chaperonin containing TCP1 subunit 8" P50990 21 29055805-29073797 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018520, HPA021051, HPA029426" Enhanced Approved "Nucleoplasm,Intermediate filaments,Cytosol" No No 1100000 "Cluster 44: Non-specific - Transcription" "Cluster 3: T-cells - Adaptive immune response" "Cluster 36: HEL - Hemostasis" "Cluster 10: Non-specific - Unknown function" "Intermediate filaments" "Nucleoplasm, Cytosol" "HPA018520: AB_1846204, HPA021051: AB_1846205, HPA029426: AB_10601796" "unprognostic (3.41e-3)" "unprognostic (2.75e-2)" "unprognostic (2.40e-3)" "unprognostic (1.62e-1)" "unprognostic (1.25e-1)" "unprognostic (4.25e-3)" "prognostic unfavorable (1.56e-5)" "unprognostic (8.78e-2)" "unprognostic (1.37e-1)" "unprognostic (3.09e-1)" "unprognostic (1.02e-2)" "unprognostic (2.91e-1)" "unprognostic (3.01e-2)" "unprognostic (8.26e-2)" "unprognostic (3.50e-2)" "unprognostic (1.25e-1)" "unprognostic (1.57e-1)" 72.7 125.0 62.5 99.1 67.0 99.5 100.4 70.3 84.0 78.5 78.0 87.9 77.9 74.8 88.2 83.7 80.9 64.3 116.3 66.9 74.7 102.7 92.7 70.1 140.8 64.5 65.3 88.0 95.3 100.0 40.6 107.0 69.0 77.1 102.1 71.3 70.7 72.5 121.1 75.0 78.6 85.5 66.7 88.9 68.8 79.1 68.7 141.2 78.5 145.2 154.3 122.3 50.3 66.1 437.4 243.1 319.4 233.3 220.4 302.3 350.9 340.5 219.1 386.2 317.5 548.6 269.0 858.8 229.1 237.1 466.8 174.4 632.2 391.7 441.1 364.0 348.1 1185.2 289.8 384.3 227.0 609.0 335.6 229.0 244.9 448.6 372.6 278.6 368.1 379.7 935.8 519.0 404.1 270.9 456.6 359.4 572.6 433.6 310.6 411.7 596.5 547.4 409.1 283.2 316.7 231.6 334.1 356.6 364.7 347.5 319.9 526.7 267.4 221.3 613.7 216.7 439.7 329.2 651.8 695.1 256.3 704.5 339.0 79.9 110.1 54.4 56.9 120.9 79.6 79.8 76.3 73.4 133.3 61.8 85.5 82.1 11.5 87.7 132.2 83.5 92.7 127.4 62.5 67.0 70.3 84.0 66.9 74.7 64.5 65.3 69.0 66.7 68.7 66.1 66.9 64.1 61.7 15.0 120.1 143.1 197.6 278.6 70.0 85.6 88.4 76.5 75.7 90.1 150.0 75.4 18.8 268.9 122.1 67.3 144.8 194.1 17.0 106.6 92.8 94.8 97.0 150.2 26.7 138.0 275.8 93.4 52.0 73.7 112.8 135.6 55.3 53.4 170.5 77.4 31.3 106.2 201.4 115.6 122.4 20.5 84.2 109.9 115.6 26.2 226.6 96.1 97.9 13.6 21.4 131.2 92.1 92.9 130.7 185.9 107.4 189.7 147.7 84.6 105.2 88.7 214.7 170.1 176.8 90.2 131.4 285.3 105.1 254.5 161.1 170.6 DES "CMD1I, CSM1, CSM2" ENSG00000175084 Desmin P17661 2 219418377-219426734 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Muscle protein" "Cancer-related genes, Cardiomyopathy, Desmin-related myopathy, Disease variant, Limb-girdle muscular dystrophy, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 13020.7;intestine: 8627.2;skeletal muscle: 16532.0" "Cell type enriched" "Detected in many" 5 "Cardiomyocytes: 2531.9" "Cancer enhanced" "Detected in all" "prostate cancer: 562.1;stomach cancer: 400.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HSkMC: 70.2;LHCN-M2: 145.3;NB-4: 39.5;RH-30: 333.1" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 5 "midbrain: 29.5" "CAB000034, HPA018803" Enhanced Supported "Intermediate filaments" NA NA 1600000 "Cluster 7: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Intermediate filaments" "CAB000034: , HPA018803: AB_1847616" "unprognostic (1.75e-1)" "unprognostic (1.95e-3)" "unprognostic (3.43e-2)" "unprognostic (8.76e-2)" "unprognostic (7.75e-3)" "unprognostic (6.61e-3)" "unprognostic (1.55e-1)" "unprognostic (2.72e-2)" "unprognostic (4.67e-1)" "unprognostic (3.84e-2)" "unprognostic (2.57e-1)" "unprognostic (7.43e-2)" "prognostic unfavorable (5.08e-4)" "unprognostic (3.49e-2)" "unprognostic (1.34e-1)" "unprognostic (1.22e-1)" "unprognostic (9.25e-3)" 235.3 57.1 2.1 436.2 4.9 1.1 51.2 2.1 9.6 504.3 5.0 8627.2 291.3 3015.2 86.0 1481.2 1085.0 452.1 13020.7 2.4 2.5 37.6 15.5 173.9 7.2 3.4 2.5 171.8 14.6 0.5 8.4 52.7 2.4 2218.8 245.6 0.0 255.3 2253.1 16532.0 152.4 1343.5 2557.5 2.1 25.2 1965.6 16.1 2.6 3.2 66.2 5753.8 1.2 4761.8 669.4 2.4 0.0 0.0 0.1 0.0 0.0 2.2 5.3 0.2 0.0 0.1 0.1 0.5 0.0 0.0 9.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.2 17.0 0.1 1.3 70.2 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 145.3 0.0 0.0 39.5 0.5 0.0 0.0 0.0 333.1 2.1 0.0 0.0 0.2 1.2 0.0 0.0 0.0 9.2 0.0 5.0 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.7 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 2.1 4.9 2.1 9.6 2.4 2.5 3.4 2.5 2.4 2.1 2.6 2.4 0.4 0.0 0.0 0.0 0.0 4.1 2.7 0.0 0.0 0.0 0.1 0.0 2531.9 1.5 0.0 0.0 0.0 1.9 0.0 0.4 0.0 0.0 90.6 0.5 6.7 22.7 0.0 0.0 0.1 0.0 5.2 104.6 0.0 0.1 0.0 0.0 1.8 0.0 5.6 0.0 0.0 0.9 0.0 0.0 10.7 71.6 28.9 2.8 12.4 0.0 0.6 0.0 0.0 0.5 0.0 0.5 0.0 50.4 0.0 8.7 0.0 0.1 0.0 0.0 46.0 497.8 210.5 5.0 5.1 0.1 9.8 8.5 2.4 0.0 0.2 2.9 DISC1 ENSG00000162946 "DISC1 scaffold protein" Q9NRI5 1 231626790-232041272 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Neurogenesis, Wnt signaling pathway" "Developmental protein" Schizophrenia "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 21.7" "Cell type enriched" "Detected in many" 4 "Rod photoreceptor cells: 113.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "THP-1: 11.4;TIME: 8.7;WM-115: 8.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA048911 Supported "Intermediate filaments,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 43: THP-1 - Innate immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Intermediate filaments, Cytosol" "HPA048911: AB_2732549" "unprognostic (1.08e-1)" "unprognostic (1.40e-1)" "unprognostic (1.58e-1)" "unprognostic (2.98e-1)" "unprognostic (2.57e-2)" "unprognostic (3.36e-2)" "unprognostic (6.69e-3)" "unprognostic (1.41e-1)" "unprognostic (9.49e-2)" "unprognostic (1.71e-1)" "unprognostic (8.89e-2)" "unprognostic (9.53e-2)" "unprognostic (1.31e-4)" "unprognostic (1.74e-2)" "unprognostic (2.02e-1)" "unprognostic (5.94e-2)" "unprognostic (1.94e-1)" 2.4 1.4 5.3 3.1 5.4 2.6 1.9 3.9 5.6 2.1 2.6 1.5 1.1 1.5 0.5 1.3 1.1 2.6 9.0 4.2 4.9 1.1 1.4 1.7 2.4 6.9 5.8 4.4 0.8 1.1 1.0 7.3 6.9 1.2 1.2 21.7 2.0 0.9 1.4 1.2 1.3 1.4 5.6 2.9 1.0 0.9 7.3 3.1 1.8 1.1 1.7 1.6 1.3 7.7 0.0 0.4 4.0 0.1 0.1 0.3 2.8 1.6 3.6 4.1 3.5 1.4 0.8 0.1 4.8 1.3 1.0 0.0 0.3 0.1 3.7 2.6 1.7 2.2 0.3 4.0 0.5 3.7 5.1 2.2 0.7 1.4 1.2 2.8 3.8 2.7 0.0 1.4 4.6 0.4 1.1 5.6 2.0 0.0 1.5 2.7 1.1 0.4 0.1 0.0 0.7 2.2 1.4 0.0 2.4 1.0 0.0 11.4 8.7 2.1 2.3 1.0 0.9 0.9 0.7 0.0 1.7 5.6 8.8 0.1 0.8 0.0 0.2 0.8 0.1 0.0 0.4 0.0 1.0 0.1 0.4 0.1 0.7 0.2 0.4 0.6 0.1 0.2 5.3 5.4 3.9 5.6 4.2 4.9 6.9 5.8 6.9 5.6 7.3 7.7 6.7 0.0 1.1 0.0 2.1 0.9 0.5 0.7 3.4 23.3 2.0 1.8 7.2 0.0 1.2 3.7 8.4 8.0 2.0 0.5 0.0 0.6 16.6 3.4 2.1 6.7 0.0 2.1 0.0 1.1 0.8 3.0 0.0 4.5 7.0 8.0 10.0 0.0 11.3 0.0 0.0 0.1 0.0 13.0 12.6 23.2 0.9 13.7 3.6 0.0 5.6 2.4 2.1 0.0 0.0 2.0 0.3 1.5 2.1 0.7 0.0 0.2 2.5 113.1 0.0 4.6 2.7 1.4 1.6 0.5 1.1 2.5 5.8 8.1 0.7 0.6 EPPK1 EPIPL1 ENSG00000261150 "Epiplakin 1" P58107 8 143857324-143878467 "Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skin 1: 16.1" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 137.1;Suprabasal keratinocytes: 274.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 14.3;EFO-21: 13.3;HaCaT: 13.8;HeLa: 26.8;MCF7: 20.2;SK-BR-3: 9.3" "Not detected" "Not detected" "HPA066808, HPA067357, HPA069333" Approved Enhanced "Intermediate filaments" NA NA 1200000 "Cluster 61: Skin - Cornification" "Cluster 20: HeLa - Mitochondria" "Cluster 28: Keratinocytes - Keratinization" "Intermediate filaments" "HPA066808: AB_2685726, HPA067357: AB_2685826, HPA069333: AB_2686123" "unprognostic (1.42e-1)" "unprognostic (9.30e-2)" "unprognostic (5.89e-2)" "prognostic unfavorable (5.52e-5)" "unprognostic (2.85e-2)" "unprognostic (5.86e-3)" "unprognostic (4.90e-2)" "unprognostic (8.73e-2)" "unprognostic (9.60e-2)" "unprognostic (2.31e-1)" "prognostic unfavorable (3.94e-4)" "unprognostic (1.35e-1)" "unprognostic (1.97e-3)" "unprognostic (5.94e-3)" "unprognostic (4.35e-1)" "unprognostic (3.68e-3)" "unprognostic (5.08e-3)" 0.2 0.0 0.4 0.3 0.4 0.1 0.9 3.9 0.5 0.5 1.3 3.3 2.1 2.4 0.3 1.7 2.0 0.2 0.1 0.8 0.6 1.2 0.3 0.9 0.1 2.5 2.7 0.0 0.7 0.2 0.2 0.2 1.7 1.4 0.6 0.0 2.2 1.4 0.2 16.1 2.7 0.9 1.6 1.2 2.1 1.8 0.7 0.1 0.2 0.0 0.2 1.8 0.9 0.4 7.9 0.1 0.1 0.0 0.0 0.0 14.3 0.0 0.0 0.0 0.0 7.4 0.5 0.0 13.3 0.0 0.0 13.8 1.4 0.1 0.0 0.0 3.4 0.0 26.8 4.6 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 20.2 0.0 0.0 1.4 1.8 0.0 0.0 0.1 0.0 0.0 4.9 2.3 0.0 2.2 9.3 0.0 1.2 7.5 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 3.9 0.5 0.8 0.6 2.5 2.7 1.7 1.6 0.7 0.4 0.7 19.2 9.2 1.0 1.1 137.1 20.3 8.2 8.0 0.6 32.7 25.0 27.9 11.5 4.4 14.7 0.0 2.5 0.0 48.1 0.0 11.3 0.5 12.6 0.5 3.2 6.0 0.0 0.3 14.7 0.3 2.4 12.2 10.1 0.0 0.6 0.7 4.4 0.3 0.0 0.0 14.5 12.2 0.0 8.2 0.3 0.0 0.4 16.0 0.0 0.0 0.6 0.0 0.0 0.1 31.9 21.7 0.0 0.2 8.6 28.2 7.0 24.2 0.2 0.0 0.0 5.2 1.5 1.0 10.6 274.3 6.2 1.2 0.1 28.4 31.5 EVPL EVPK ENSG00000167880 Envoplakin Q92817 17 76004502-76027306 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 281.2;skin 1: 147.4;vagina: 101.9" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 26.7;Squamous epithelial cells: 94.1;Suprabasal keratinocytes: 25.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 59.8;MCF7: 40.4;RT4: 87.8;SK-BR-3: 43.2;T-47d: 54.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002220, HPA053969" Enhanced Supported "Intermediate filaments,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" Cytosol "CAB002220: AB_563701, HPA053969: AB_2682326" "unprognostic (2.10e-1)" "unprognostic (1.58e-1)" "unprognostic (1.41e-1)" "unprognostic (4.21e-1)" "unprognostic (1.05e-2)" "unprognostic (1.87e-2)" "unprognostic (1.70e-1)" "unprognostic (1.11e-1)" "unprognostic (1.94e-1)" "unprognostic (1.44e-1)" "unprognostic (7.40e-3)" "unprognostic (2.64e-1)" "unprognostic (2.40e-2)" "unprognostic (2.31e-1)" "unprognostic (3.47e-1)" "unprognostic (7.93e-2)" "unprognostic (3.09e-2)" 1.3 0.3 0.6 1.0 0.6 2.5 2.6 1.1 1.0 47.5 0.8 8.9 11.0 1.5 1.7 281.2 2.1 1.7 0.2 0.6 0.3 17.0 0.3 9.4 0.6 2.8 1.3 0.3 4.0 3.4 1.5 0.3 2.8 8.0 1.5 0.6 42.3 1.8 1.4 147.4 9.1 1.0 0.5 0.3 5.2 0.8 0.6 0.4 10.7 0.1 7.9 12.7 101.9 1.5 28.1 23.4 0.0 0.3 0.2 0.0 9.6 0.2 0.0 0.0 0.0 2.6 16.7 0.0 0.1 0.0 0.0 59.8 0.1 7.8 0.1 0.1 0.2 0.7 19.4 17.4 0.0 0.2 4.2 0.2 12.3 0.2 0.0 0.0 0.0 3.7 0.1 1.1 0.0 40.4 1.0 3.6 0.1 11.9 10.5 11.5 0.1 0.4 16.7 87.8 1.1 0.0 11.4 43.2 0.0 0.2 54.1 0.8 0.0 0.0 0.1 0.2 0.1 0.1 0.2 0.1 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.3 0.0 0.2 0.1 0.0 0.6 0.6 1.1 1.0 0.6 0.3 2.8 1.3 2.8 0.5 0.6 1.5 0.2 19.2 19.5 0.0 0.0 11.7 4.7 10.5 26.7 0.3 5.1 2.9 3.7 4.3 16.5 5.5 0.0 0.2 0.2 10.8 1.9 4.4 0.0 4.3 0.6 0.3 20.4 1.3 0.3 0.5 0.2 0.5 12.8 8.9 12.6 0.2 0.0 0.0 0.0 0.0 0.1 5.7 2.0 0.6 2.1 0.1 0.9 0.2 1.8 0.0 0.1 0.0 0.0 0.0 0.1 8.4 7.4 1.9 1.2 4.6 19.3 3.4 13.1 0.1 0.0 0.7 0.7 0.1 1.2 94.1 25.9 0.0 0.4 0.4 15.5 12.9 GFAP FLJ45472 ENSG00000131095 "Glial fibrillary acidic protein" P14136 17 44903159-44916937 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 13076.3" "Cell type enriched" "Detected in some" 7 "Astrocytes: 381.9" "Cancer enriched" "Detected in some" 368 "glioma: 2468.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 6.2" "Group enriched" "Detected in many" 5 "granulocytes: 6.2;NK-cells: 1.7" "Cell line enhanced" "Detected in many" "U-87 MG: 6.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000039, HPA056030, HPA063513" Enhanced Supported Supported "Intermediate filaments" No No 170000000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 70: Brain - Nervous system development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 64: Astrocytes - Nervous system maintenance" "Intermediate filaments" "CAB000039: AB_10013382, HPA056030: AB_2683015, HPA063513: AB_2685027" "unprognostic (1.79e-2)" "unprognostic (2.74e-1)" "unprognostic (9.83e-2)" "unprognostic (2.12e-5)" "unprognostic (4.08e-1)" "unprognostic (5.09e-1)" "unprognostic (1.26e-1)" "unprognostic (6.53e-2)" "unprognostic (6.57e-3)" "unprognostic (7.35e-2)" "unprognostic (5.86e-2)" "unprognostic (1.24e-1)" "unprognostic (7.63e-2)" "unprognostic (2.75e-5)" "unprognostic (1.49e-1)" "unprognostic (1.66e-1)" "unprognostic (1.64e-1)" 1.9 1.8 5096.2 2.2 5407.4 14.1 3.5 5902.8 4887.4 1.9 2342.2 1.4 0.4 0.9 1.5 3.7 2.2 1.6 8.2 5059.3 9869.7 2.1 1.7 1.3 1.9 13076.3 9001.4 2.1 1.5 1.6 33.9 0.7 9204.1 1.3 1.0 117.7 1.9 1.0 2.1 2.6 0.7 0.9 10040.2 1.5 1.5 1.4 8068.5 0.4 1.7 0.3 1.1 1.4 0.9 10496.9 1.0 0.7 1.2 2.3 0.0 0.4 0.2 1.0 1.2 1.5 1.2 1.3 1.5 2.2 1.9 0.5 0.9 2.7 1.4 0.4 1.8 3.0 1.1 1.4 2.1 0.9 0.0 0.2 2.2 0.1 0.8 1.0 0.0 1.7 0.0 2.3 0.7 5.3 0.8 1.3 1.9 2.6 1.6 0.1 3.3 0.7 0.7 1.2 0.7 0.6 1.6 1.8 0.1 1.7 0.2 1.0 1.2 1.2 0.7 1.2 0.9 1.1 2.0 0.7 1.6 1.6 6.1 2.0 2.7 1.5 0.8 0.3 0.3 0.6 0.2 0.2 0.2 0.4 0.1 0.5 0.3 0.4 6.2 1.7 0.5 0.5 0.2 0.2 5096.2 5407.4 5902.8 4887.4 5059.3 9869.7 13076.3 9001.4 9204.1 10040.2 8068.5 10496.9 0.0 0.0 0.0 381.9 0.1 0.0 0.1 0.0 0.0 0.8 1.3 0.6 5.2 0.0 0.0 0.0 6.2 0.0 0.1 0.0 0.0 0.3 0.1 0.1 0.1 0.8 0.0 0.0 0.5 0.2 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 3.7 0.0 53.5 0.0 10.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 4.4 0.0 0.2 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 KRT13 "CK13, K13, MGC161462, MGC3781" ENSG00000171401 "Keratin 13" P13646 17 41500981-41505705 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 40925.1;vagina: 13409.3" "Cell type enriched" "Detected in many" 4 "Squamous epithelial cells: 16844.0" "Group enriched" "Detected in many" 5 "cervical cancer: 899.2;head and neck cancer: 758.7;urothelial cancer: 504.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 93 "A-431: 2462.5;HaCaT: 1626.2" "CAB000133, HPA030877, HPA069771" Enhanced Enhanced "Intermediate filaments" NA NA 680000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "CAB000133: , HPA030877: AB_2673641, HPA069771: AB_2732141" "unprognostic (1.45e-1)" "unprognostic (6.23e-2)" "unprognostic (1.37e-1)" "unprognostic (2.19e-2)" "unprognostic (9.30e-5)" "unprognostic (7.30e-3)" "unprognostic (1.95e-1)" "unprognostic (1.77e-1)" "unprognostic (5.81e-3)" "prognostic unfavorable (1.02e-4)" "unprognostic (3.16e-1)" "prognostic unfavorable (1.45e-6)" "unprognostic (1.80e-1)" "unprognostic (2.76e-1)" "unprognostic (3.04e-2)" "unprognostic (4.33e-1)" 7.7 7.5 0.0 0.0 0.1 6.8 5.1 0.0 0.0 6884.6 0.0 5.6 0.1 10.2 0.0 40925.1 7.0 8.8 9.2 0.0 0.1 5.6 12.8 6.0 0.3 0.0 0.0 9.9 17.2 0.0 26.9 0.0 0.0 115.2 0.0 0.0 6881.1 3.8 9.8 20.5 8.5 14.2 0.0 7.7 31.3 6.9 0.0 13.6 6.1 0.0 1855.2 924.7 13409.3 0.0 2462.5 0.6 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.6 0.8 7.1 0.6 0.0 0.0 1626.2 0.0 0.4 0.0 1.4 0.0 4.5 21.8 0.0 0.0 1.7 1.3 0.0 0.8 0.0 0.0 0.3 0.0 0.0 5.4 1.2 0.0 1.3 0.1 0.1 0.1 14.8 0.3 0.2 1.2 0.3 0.0 10.7 0.0 0.0 1.9 2.0 7.7 0.0 2.3 6.4 5.1 0.0 0.4 0.0 6.6 0.3 6.3 5.8 1.9 4.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 16.0 1.1 0.0 0.9 2.8 545.6 17.1 146.8 0.0 2.3 4.6 0.6 1.5 94.5 0.0 0.0 0.1 0.2 0.6 0.0 0.0 1.2 2.7 0.2 11.4 1.2 5.5 0.0 0.0 0.5 12.6 0.0 4.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 8.2 0.0 0.0 3.2 55.9 13.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.7 286.6 27.1 227.9 0.1 0.1 3.3 0.0 0.0 0.0 16.9 0.2 0.6 16844.0 1.6 0.4 8.8 0.0 0.4 3645.4 KRT14 "EBS3, EBS4" ENSG00000186847 "Keratin 14" P02533 17 41582279-41586895 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Ectodermal dysplasia, Epidermolysis bullosa, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 6940.5" "Group enriched" "Detected in many" 9 "Basal keratinocytes: 35588.3;Suprabasal keratinocytes: 11677.1" "Cancer enriched" "Detected in many" 5 "head and neck cancer: 5910.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 4065.2;HBEC3-KT: 2003.9;hTCEpi: 2448.6;hTERT-HME1: 794.2;U-2197: 696.0" "Not detected" "Not detected" "Region enriched" "Detected in many" 7 "spinal cord: 36.3" "CAB000134, HPA000452, HPA000539, HPA023040" Enhanced Enhanced "Intermediate filaments" NA NA 1600000000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Intermediate filaments" "CAB000134: , HPA000452: AB_1079177, HPA000539: , HPA023040: AB_1852201" "prognostic favorable (2.66e-4)" "unprognostic (1.64e-1)" "unprognostic (1.01e-2)" "unprognostic (1.42e-2)" "unprognostic (1.66e-1)" "unprognostic (1.02e-2)" "unprognostic (2.03e-2)" "unprognostic (2.74e-1)" "unprognostic (1.35e-1)" "unprognostic (1.00e-2)" "unprognostic (5.74e-3)" "unprognostic (1.49e-8)" "unprognostic (8.91e-2)" "unprognostic (2.00e-1)" "unprognostic (8.80e-3)" "unprognostic (1.22e-2)" 15.8 1.2 0.0 0.0 0.0 2.7 332.7 0.0 0.0 412.0 0.0 1.7 0.0 0.9 0.0 1304.2 1.7 0.0 3.5 0.0 0.0 0.8 2.5 1.7 0.0 0.0 0.0 1.3 2.9 0.0 4.3 2.2 0.1 29.1 0.0 0.0 702.1 3.8 15.9 6940.5 2.1 0.1 0.0 0.9 1.7 1.5 0.0 186.7 2.3 0.0 262.3 0.7 846.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.8 0.1 0.0 0.3 0.0 0.0 0.0 0.6 0.1 0.7 0.0 4065.2 0.0 2003.9 0.2 0.0 0.0 0.1 1.6 0.0 0.1 0.2 2.5 0.1 2448.6 3.0 794.2 0.0 0.1 0.0 0.5 3.6 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.6 0.2 0.6 0.0 0.1 0.1 0.0 0.2 0.5 0.0 0.0 0.4 0.0 0.3 9.1 1.7 696.0 0.0 0.9 0.0 0.0 3.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.5 35588.3 1072.7 181.5 2407.4 0.0 103.5 740.9 0.3 0.0 6.0 0.0 0.0 17.9 3.2 7.3 0.0 0.1 0.0 0.1 0.0 129.0 0.0 0.0 0.0 0.0 127.0 116.5 0.0 0.2 0.0 0.0 0.0 0.0 3.3 0.0 0.0 3.4 0.0 0.0 1833.4 0.0 0.0 9.3 1990.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 3.5 0.0 9.9 702.0 96.8 0.0 2.3 0.0 0.0 0.0 96.3 0.0 0.1 83.2 11677.1 2.5 62.1 0.1 2.3 100.0 KRT15 "CK15, K15, K1CO" ENSG00000171346 "Keratin 15" P19012 17 41513745-41522529 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "breast: 419.1;esophagus: 1156.7;skin 1: 1319.5;vagina: 423.3" "Group enriched" "Detected in many" 4 "Basal prostatic cells: 2789.9;Basal squamous epithelial cells: 8290.4;Squamous epithelial cells: 4637.9" "Cancer enhanced" "Detected in many" "cervical cancer: 178.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 10 "HaCaT: 1156.8;hTCEpi: 1001.5" "Region enhanced" "Detected in single" "white matter: 1.9" "Not detected" "Not detected" "HPA023910, HPA024554" Enhanced Supported "Nucleoplasm,Intermediate filaments" No No 480000000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" Nucleoplasm "HPA023910: AB_1852205, HPA024554: AB_1852207" "prognostic favorable (4.50e-4)" "unprognostic (9.14e-2)" "unprognostic (3.28e-2)" "unprognostic (1.19e-3)" "unprognostic (3.57e-2)" "unprognostic (8.84e-2)" "unprognostic (6.12e-3)" "unprognostic (1.70e-1)" "unprognostic (2.13e-1)" "unprognostic (8.65e-3)" "unprognostic (9.91e-3)" "unprognostic (2.09e-1)" "unprognostic (2.24e-11)" "unprognostic (6.91e-3)" "unprognostic (2.62e-1)" "unprognostic (1.33e-5)" "unprognostic (5.35e-2)" 4.7 0.3 0.1 0.2 0.0 0.7 419.1 0.0 0.1 148.2 0.2 1.1 1.5 0.3 2.2 1156.7 32.4 2.8 0.7 0.1 0.0 0.3 0.6 4.3 0.0 0.1 0.1 0.4 1.4 0.0 1.2 0.3 0.1 182.8 1.6 0.0 140.0 4.1 0.7 1319.5 2.3 0.1 0.0 0.3 1.6 8.0 0.1 93.7 0.5 0.0 77.6 9.5 423.3 0.1 56.4 7.4 0.0 0.0 0.0 0.0 0.7 5.3 1.3 0.3 0.2 5.9 20.2 0.0 1.8 0.6 14.0 1156.8 0.0 41.8 0.2 0.6 0.0 0.0 7.7 1.9 0.0 0.1 4.7 0.0 1001.5 2.2 6.9 2.7 3.4 0.0 0.3 0.5 0.2 3.5 0.1 0.5 0.0 3.9 6.2 0.0 0.0 104.9 3.3 5.9 2.6 0.1 1.1 15.0 1.2 0.3 20.3 0.0 18.6 0.3 2.8 0.3 2.2 0.1 0.1 0.0 8.3 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 6.1 12.8 10.3 0.0 2.7 1309.8 2789.9 1190.9 8290.4 0.6 577.7 670.3 0.8 5.7 287.5 1.8 0.0 0.7 16.9 18.3 1.9 8.5 117.6 4.1 0.7 22.9 4.8 0.0 0.1 7.5 7.7 21.7 4.6 8.2 2.5 0.0 0.0 0.0 0.4 0.0 0.1 10.3 189.2 0.0 61.7 44.4 1.5 17.2 320.2 0.0 0.0 0.2 0.0 0.0 0.1 14.1 10.5 0.4 88.7 872.9 8.6 0.1 57.7 0.6 0.0 0.4 32.1 0.6 0.8 4637.9 193.6 1.2 21.6 0.1 7.2 906.0 KRT17 PCHC1 ENSG00000128422 "Keratin 17" Q04695 17 41619442-41624842 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 382.1;skin 1: 949.4;urinary bladder: 632.2" "Group enriched" "Detected in many" 5 "Basal prostatic cells: 13196.1;Prostatic glandular cells: 5931.6;Urothelial cells: 8499.3" "Cancer enhanced" "Detected in all" "head and neck cancer: 3317.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "hTCEpi: 20287.9;SiHa: 8539.7" "Not detected" "Not detected" "CAB000029, HPA000452, HPA000453, HPA000539, HPA045062" Enhanced Enhanced "Intermediate filaments" Yes No 610000000 "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Intermediate filaments" "CAB000029: AB_2133155, HPA000452: AB_1079177, HPA000453: AB_1079176, HPA000539: , HPA045062: AB_2679204" "prognostic favorable (4.44e-4)" "unprognostic (1.43e-1)" "unprognostic (1.15e-1)" "unprognostic (3.65e-3)" "unprognostic (4.46e-2)" "unprognostic (4.34e-1)" "unprognostic (4.36e-3)" "unprognostic (1.32e-2)" "unprognostic (2.27e-1)" "unprognostic (1.29e-1)" "unprognostic (7.86e-3)" "unprognostic (1.53e-1)" "prognostic unfavorable (5.74e-4)" "unprognostic (1.82e-1)" "unprognostic (1.77e-1)" "unprognostic (2.20e-1)" "unprognostic (3.89e-1)" 5.1 0.4 4.9 0.8 5.3 2.8 382.1 3.5 5.8 102.2 3.5 2.0 0.8 4.3 14.1 320.4 6.9 1.9 2.7 6.3 3.3 3.1 0.6 9.8 0.3 3.5 3.4 0.9 2.6 0.5 6.6 7.0 3.5 132.4 0.3 0.3 263.2 116.1 0.9 949.4 0.6 1.0 3.4 0.4 2.3 4.5 3.3 142.7 1.6 0.0 97.8 632.2 212.3 4.7 212.5 0.2 0.0 0.0 0.8 0.9 48.8 1.9 0.4 2.8 2.7 16.8 1.9 1.0 14.7 0.2 0.4 2101.7 0.1 2129.1 1.9 0.3 1.6 2.0 910.8 2.0 0.5 1.9 2.2 0.4 20287.9 1.3 1539.9 0.0 1.0 0.0 1.0 1.5 0.4 0.7 0.7 0.3 0.4 237.2 0.0 0.7 3.1 1.7 0.8 770.5 0.3 0.2 8539.7 3.8 0.9 4.8 0.3 1.4 0.8 0.0 401.5 0.2 1.0 0.9 0.4 3.1 1.4 77.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 5.3 3.5 5.8 6.3 3.3 3.5 3.4 3.5 3.4 3.3 4.7 5.6 22.4 7.2 0.3 0.5 139.6 13196.1 338.0 327.8 0.2 158.4 792.8 0.1 0.0 415.8 36.8 0.0 21.5 3.8 0.9 0.0 567.7 0.4 116.9 13.5 54.5 1.8 0.0 3.2 202.1 148.5 87.9 0.0 134.1 3.8 0.0 0.0 0.0 3.8 20.2 0.5 0.6 36.7 0.0 14.1 1.6 2.1 37.5 10.6 3.7 6.7 0.0 0.0 0.5 1.4 1754.5 2.5 212.5 0.0 5931.6 0.1 0.4 100.1 0.0 0.0 0.9 101.0 0.3 0.4 48.2 124.3 5.7 60.8 3.1 0.8 8499.3 KRT19 "CK19, K19, K1CS, MGC15366" ENSG00000171345 "Keratin 19" P08727 17 41523617-41528308 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 889.0;salivary gland: 810.7;urinary bladder: 781.4" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 7444.0;Club cells: 5055.9;Ductal cells: 4717.9;Extravillous trophoblasts: 6919.3;Pancreatic endocrine cells: 7374.9;Proximal enterocytes: 8623.3;Urothelial cells: 5959.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 1945.3;HBEC3-KT: 2945.0;MCF7: 2220.9;RT4: 3146.7;SK-BR-3: 5446.1;T-47d: 3674.2" "Not detected" "Not detected" "CAB000031, HPA002465" Enhanced Supported "Intermediate filaments" NA NA 300000000 "Cluster 40: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Intermediate filaments" "CAB000031: AB_2234418, HPA002465: AB_1079179" "unprognostic (1.09e-1)" "unprognostic (1.83e-1)" "unprognostic (3.86e-2)" "unprognostic (1.59e-2)" "unprognostic (2.24e-2)" "unprognostic (1.13e-1)" "unprognostic (2.29e-1)" "unprognostic (2.80e-2)" "unprognostic (3.14e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (6.82e-5)" "unprognostic (1.90e-2)" "prognostic unfavorable (2.98e-5)" "unprognostic (3.52e-2)" "unprognostic (2.14e-1)" "unprognostic (3.08e-2)" "unprognostic (2.35e-2)" 89.3 18.7 2.0 61.7 2.4 0.3 403.3 7.9 2.5 250.0 1.6 525.7 348.3 57.9 72.0 889.0 176.1 298.6 13.5 1.5 1.7 141.8 7.7 204.1 0.4 1.6 2.9 74.4 48.8 14.3 15.6 175.1 2.2 208.3 359.2 0.1 810.7 194.2 1.3 141.9 776.1 46.5 1.4 1.2 631.5 3.4 1.8 127.8 28.3 1.6 98.3 781.4 317.0 1.8 2.6 343.4 0.0 6.3 0.7 1.8 1169.3 412.1 0.5 12.8 2.9 992.6 1945.3 0.4 393.3 199.0 1.5 1044.6 0.1 2945.0 2.5 0.8 10.4 0.2 213.4 692.3 30.3 0.0 82.0 0.7 524.9 9.0 0.4 0.2 26.2 0.0 148.4 2.5 0.1 2220.9 5.9 3.0 18.5 1323.5 492.7 2.9 0.1 5.8 1335.4 3146.7 40.0 1.7 3.3 5446.1 0.1 266.5 3674.2 0.3 1.7 3.6 6.1 7.7 0.7 1.1 0.8 2.0 1.5 0.3 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.0 2.4 7.9 2.5 1.5 1.7 1.6 2.9 2.2 1.4 1.8 1.8 10.5 673.1 185.5 0.0 17.8 5.2 4317.3 7444.0 1715.8 0.0 1393.0 867.5 2.9 662.0 5055.9 892.0 0.0 1160.8 20.5 3599.6 1.9 4717.9 0.1 737.2 102.8 41.9 362.5 0.0 0.1 2589.9 6919.3 171.8 1571.4 1010.7 94.6 1.0 1.1 0.7 179.0 0.0 0.1 1382.4 2720.0 2.6 2.5 2.6 37.9 25.5 190.3 1.0 30.0 0.8 0.0 0.0 0.0 7374.9 3399.6 88.8 19.9 2228.8 8623.3 26.7 1954.3 0.0 0.0 0.0 240.0 1.1 1.6 1302.6 1.1 2127.5 36.1 4.8 1619.0 5959.8 KRT4 "CK4, CYK4, K4" ENSG00000170477 "Keratin 4" P19013 12 52806549-52814116 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "esophagus: 19735.6" "Cell type enriched" "Detected in some" 18 "Squamous epithelial cells: 5828.7" "Group enriched" "Detected in many" 5 "cervical cancer: 94.3;head and neck cancer: 151.8;stomach cancer: 73.1;urothelial cancer: 38.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 33 "HaCaT: 734.9;SK-BR-3: 361.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002154, HPA034881" Enhanced Supported "Intermediate filaments" NA NA 600000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "CAB002154: AB_563803, HPA034881: AB_2674370" "unprognostic (4.04e-1)" "unprognostic (3.22e-3)" "unprognostic (5.16e-3)" "unprognostic (8.52e-3)" "unprognostic (1.20e-1)" "unprognostic (2.64e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (3.26e-4)" "unprognostic (2.85e-3)" "unprognostic (2.84e-2)" "unprognostic (2.58e-11)" "unprognostic (1.64e-1)" "unprognostic (6.97e-2)" "unprognostic (1.16e-1)" "prognostic unfavorable (6.26e-4)" 1.5 1.5 0.0 0.0 0.0 0.0 0.9 0.0 0.0 513.5 0.0 1.1 0.0 1.2 0.0 19735.6 9.5 3.1 7.2 0.0 0.0 0.9 2.6 17.3 0.0 0.0 0.0 1.8 2.8 0.0 8.9 0.0 0.0 4.3 0.0 0.0 2124.1 0.0 2.6 3.9 1.7 0.9 0.0 1.5 8.6 0.8 0.0 2.0 1.0 0.1 1418.0 4.4 1040.2 0.0 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 1.8 0.0 0.1 0.0 734.9 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.5 1.3 0.0 0.9 0.0 0.0 0.0 0.0 0.0 1.9 0.3 0.0 1.4 0.0 0.2 0.0 15.5 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.0 1.0 361.6 0.0 0.0 2.0 0.0 2.0 0.0 0.2 0.0 0.0 0.0 1.0 0.9 0.5 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.4 3.3 0.0 0.0 0.0 6.5 36.9 23.3 0.0 0.5 2.9 0.5 0.0 308.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.6 0.2 2.9 0.0 0.0 0.0 0.0 0.0 2.6 0.0 1.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 28.5 0.0 0.0 0.1 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.9 6.9 0.0 0.1 53.7 0.0 0.0 0.0 5.3 0.0 0.1 5828.7 0.0 0.0 2.0 0.0 0.0 54.4 KRT6A "CK6C, CK6D, K6C, K6D, KRT6C, KRT6D" ENSG00000205420 "Keratin 6A" P02538 12 52487176-52493257 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Allergen, Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "cervix: 2523.3;esophagus: 7338.5;vagina: 4945.4" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 674.0;Club cells: 200.5;Squamous epithelial cells: 876.0;Suprabasal keratinocytes: 151.4;Urothelial cells: 306.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 3892.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "hTCEpi: 9761.7" "HPA045697, HPA061168" Supported Enhanced "Intermediate filaments" NA NA 4500000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "HPA045697: AB_2679422, HPA061168: AB_2684440" "unprognostic (8.10e-3)" "unprognostic (2.11e-1)" "unprognostic (2.78e-2)" "unprognostic (1.06e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.45e-4)" "unprognostic (2.43e-1)" "unprognostic (3.73e-2)" "unprognostic (1.31e-3)" "unprognostic (1.29e-1)" "unprognostic (2.89e-9)" "unprognostic (8.80e-2)" "unprognostic (7.20e-2)" "unprognostic (1.72e-1)" "unprognostic (2.13e-2)" 3.1 1.5 0.0 1.9 0.0 0.1 6.9 0.0 0.0 2523.3 0.0 1.2 0.0 1.3 0.0 7338.5 9.1 0.9 1.8 0.0 0.0 1.1 2.6 3.4 0.0 0.0 0.0 2.3 3.3 0.0 3.1 8.8 0.0 5.0 0.0 0.0 1025.5 0.0 1.9 480.0 1.3 0.4 0.0 1.4 4.9 1.0 0.0 33.6 1.5 0.0 628.6 19.7 4945.4 0.0 1.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 3.9 0.0 0.0 1143.8 0.0 2414.3 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.5 0.6 0.3 9761.7 0.2 306.7 0.0 0.3 0.0 0.7 0.8 0.0 0.0 0.0 0.0 0.0 14.0 0.3 0.1 0.5 0.0 0.3 0.0 0.0 0.0 20.4 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.5 0.0 0.0 0.2 0.2 0.4 0.9 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 105.5 79.0 674.0 12.0 0.0 0.6 1.7 0.0 0.0 200.5 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 2.6 0.2 0.8 0.0 0.0 0.0 0.0 0.0 1.8 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.7 0.0 5.5 0.0 0.0 0.7 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 100.4 0.0 0.0 24.5 0.0 0.0 0.0 11.8 0.0 0.0 876.0 151.4 0.0 1.7 0.0 0.1 306.8 KRT8 "CARD2, CK8, CYK8, K2C8, K8, KO" ENSG00000170421 "Keratin 8" P05787 12 52897187-52949954 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1335.5;stomach 1: 800.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 4302.8;Ductal cells: 6037.3;Exocrine glandular cells: 5457.6;Extravillous trophoblasts: 5323.4;Pancreatic endocrine cells: 5278.1;Paneth cells: 4937.3;Proximal enterocytes: 6802.6;Syncytiotrophoblasts: 5268.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 1.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 6130.6;BEWO: 3998.7;CACO-2: 7686.4;CAPAN-2: 4774.8;MCF7: 10521.8;SK-BR-3: 5126.4;T-47d: 4325.7" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 10 "spinal cord: 44.0" "CAB000131, CAB001696, HPA049866" Enhanced Supported "Intermediate filaments" NA NA 1700000000 "Cluster 15: NK-cells - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Intermediate filaments" "CAB000131: AB_2281144, CAB001696: , HPA049866: AB_2680923" "unprognostic (5.72e-2)" "unprognostic (2.29e-1)" "unprognostic (2.49e-2)" "unprognostic (1.52e-1)" "unprognostic (2.76e-2)" "unprognostic (4.86e-3)" "unprognostic (3.10e-2)" "unprognostic (2.52e-2)" "unprognostic (1.92e-1)" "unprognostic (4.58e-1)" "prognostic unfavorable (1.51e-4)" "unprognostic (8.99e-2)" "unprognostic (2.08e-2)" "unprognostic (2.83e-2)" "unprognostic (3.18e-1)" "unprognostic (3.68e-1)" "unprognostic (1.19e-2)" 135.0 43.6 2.2 158.6 1.3 1.0 113.8 2.0 1.6 183.4 21.3 1079.2 1112.0 34.7 66.4 48.2 134.3 217.5 147.8 1.9 1.9 240.2 463.9 172.5 7.9 8.3 4.5 10.3 654.1 59.9 278.7 368.7 8.8 151.6 564.2 0.4 318.0 73.6 1.5 49.3 1335.5 50.6 0.4 16.3 800.1 7.6 4.9 47.6 237.5 0.3 13.8 209.0 36.7 1.7 2787.7 6130.6 0.2 7.8 0.7 3.2 3998.7 11.1 47.9 6.1 6.3 7686.4 4774.8 1.1 1130.2 14.7 6.9 947.1 17.6 752.6 5.9 4.6 130.8 4.3 1184.4 2234.2 212.8 1.2 2.4 9.5 12.6 14.8 50.8 419.9 17.0 1.0 484.7 1.7 0.1 10521.8 6.5 10.6 418.5 2740.6 132.8 3.8 2.2 15.2 1198.1 1354.5 129.9 5.0 1063.2 5126.4 7.8 1263.8 4325.7 10.5 18.8 5.7 443.4 9.3 10.0 1.6 7.0 7.6 3.3 1.7 13.4 1.3 0.1 0.2 0.2 0.2 0.1 0.1 0.1 0.1 0.7 0.2 0.1 0.1 0.4 0.5 0.1 1.7 0.1 0.2 2.2 1.3 2.0 1.6 1.9 1.9 8.3 4.5 8.8 0.4 4.9 1.7 7.7 400.6 176.5 0.3 26.9 6.0 1948.0 684.7 303.3 2.3 521.6 342.8 30.2 1069.5 734.8 491.1 0.0 2208.2 8.5 4302.8 297.4 6037.3 13.9 419.2 41.0 42.3 942.5 8.6 0.5 5457.6 5323.4 94.7 1740.1 557.1 76.3 88.0 24.3 310.9 252.2 1.7 0.5 2876.3 1625.5 9.9 7.2 69.9 8.1 22.2 131.6 0.0 55.0 3.4 1.0 1.0 0.3 5278.1 4937.3 1.9 6.6 994.7 6802.6 569.1 594.8 4.3 0.0 2.2 167.4 2.0 11.4 258.9 1.7 5268.8 33.4 13.4 2337.3 1542.5 KRT80 KB20 ENSG00000167767 "Keratin 80" Q6KB66 12 52168996-52192014 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skin 1: 219.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 25.9;Ductal cells: 63.0;Endometrial ciliated cells: 33.0;Glandular and luminal cells: 33.5;Pancreatic endocrine cells: 48.4;Suprabasal keratinocytes: 37.4;Syncytiotrophoblasts: 58.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 202.5;MCF7: 287.3;SK-BR-3: 127.7;U-2 OS: 174.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA077836, HPA077918" Enhanced "Intermediate filaments" No No 230000000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 1: Pancreatic cells - Digestion" "Intermediate filaments" "HPA077836: AB_2686857, HPA077918: AB_2686871" "prognostic unfavorable (1.05e-4)" "unprognostic (5.45e-3)" "unprognostic (5.35e-2)" "unprognostic (9.19e-3)" "unprognostic (2.85e-4)" "unprognostic (6.68e-2)" "unprognostic (2.06e-3)" "unprognostic (1.26e-3)" "unprognostic (5.60e-2)" "unprognostic (4.06e-2)" "unprognostic (7.06e-3)" "unprognostic (1.02e-1)" "unprognostic (8.79e-3)" "unprognostic (8.85e-2)" "unprognostic (2.03e-1)" "unprognostic (1.51e-1)" "unprognostic (2.98e-2)" 0.4 5.3 0.0 0.3 0.0 0.1 8.7 0.3 0.6 18.5 0.0 0.1 0.5 1.2 0.9 51.0 3.4 2.7 0.3 0.1 0.0 2.7 0.7 3.4 0.0 0.0 0.0 0.2 11.6 7.0 0.4 7.3 0.0 1.5 0.1 0.5 24.8 3.4 1.3 219.1 0.3 0.1 0.0 0.1 0.5 0.3 0.0 0.8 0.8 0.0 41.1 9.9 36.5 0.0 202.5 66.7 0.0 0.0 0.0 0.0 54.2 2.9 1.8 15.3 4.6 4.5 85.9 0.0 94.4 2.3 99.4 98.5 0.0 1.3 5.3 0.4 0.0 0.0 99.4 2.4 10.1 0.1 0.1 1.1 11.9 3.5 23.0 70.2 23.2 0.0 0.0 0.1 5.4 287.3 0.2 0.1 0.4 58.5 10.1 0.2 79.4 3.0 87.1 35.7 24.5 1.3 50.1 127.7 1.2 5.6 24.1 1.0 13.5 0.3 174.4 0.2 71.6 0.1 0.3 0.5 18.0 7.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 6.2 3.9 4.4 0.0 0.0 14.7 4.6 0.4 10.0 9.4 11.0 0.0 25.9 0.1 0.3 0.0 63.0 0.9 33.0 3.7 0.5 0.0 0.0 0.1 20.4 3.4 0.4 0.0 33.5 0.0 0.6 0.0 0.0 2.0 0.0 0.0 0.1 12.2 0.0 1.6 0.5 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 48.4 0.0 0.0 0.0 4.8 0.1 1.8 21.7 0.0 0.0 0.4 2.2 0.1 0.0 2.9 37.4 58.3 0.3 0.3 0.3 8.5 NEFM "NEF3, NF-M, NFM" ENSG00000104722 "Neurofilament medium" P07197 8 24913758-24919098 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 689.9" "Cell type enhanced" "Detected in many" "Early spermatids: 92.6;Excitatory neurons: 46.6;Late spermatids: 114.6;Rod photoreceptor cells: 69.1;Spermatocytes: 43.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 25 "HEK 293: 3890.8" "CAB010900, CAB012976, HPA022845, HPA023138" Enhanced Enhanced "Intermediate filaments" Yes NA 220000 "Cluster 70: Brain - Nervous system development" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 46: Photoreceptor cells - Phototransduction" "Intermediate filaments" "CAB010900: AB_477261, CAB012976: AB_2533154, HPA022845: AB_1854399, HPA023138: AB_1854398" "unprognostic (1.41e-2)" "unprognostic (1.83e-1)" "unprognostic (2.59e-2)" "unprognostic (9.38e-2)" "unprognostic (5.17e-2)" "unprognostic (6.32e-3)" "unprognostic (6.10e-3)" "unprognostic (2.57e-1)" "unprognostic (8.55e-3)" "unprognostic (2.95e-2)" "unprognostic (1.84e-1)" "unprognostic (1.69e-2)" "unprognostic (1.38e-2)" "unprognostic (1.92e-1)" "unprognostic (4.76e-2)" "unprognostic (2.61e-2)" 0.3 19.5 61.1 0.9 27.9 0.0 0.1 150.0 689.9 9.6 0.0 2.8 0.1 4.0 0.0 4.0 5.3 0.2 0.2 57.7 54.0 1.9 0.1 0.2 0.1 610.3 89.1 1.7 2.0 0.0 17.9 0.2 487.1 1.5 0.7 90.8 0.3 27.6 1.7 0.6 1.3 2.5 86.8 0.1 0.9 18.9 430.5 1.7 0.1 0.7 0.5 0.4 6.5 203.6 0.0 0.0 154.3 0.0 0.0 0.0 0.0 2.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3890.8 0.0 0.0 0.0 79.4 0.0 0.1 2.4 0.1 0.6 0.0 0.0 0.0 0.7 0.0 0.2 5.9 0.0 0.0 0.0 30.1 0.0 0.0 0.0 0.0 0.0 0.7 0.1 3.7 32.6 0.0 0.0 0.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.1 27.9 150.0 689.9 57.7 54.0 610.3 89.1 487.1 86.8 430.5 203.6 3.1 0.0 0.0 12.4 0.0 1.3 0.2 0.1 9.1 30.9 1.1 21.2 2.4 0.0 0.6 0.0 6.2 0.0 3.2 0.1 0.0 0.1 92.6 0.7 19.5 2.9 3.5 0.0 46.6 0.2 0.0 2.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 20.2 17.5 0.0 0.0 0.0 0.7 114.6 0.9 0.7 1.8 13.1 0.0 22.8 0.0 9.5 13.6 0.0 0.0 4.5 0.4 0.3 0.0 0.4 0.0 69.1 0.0 3.3 5.7 43.8 1.0 14.0 0.3 0.0 4.1 0.0 0.1 0.4 NES FLJ21841 ENSG00000132688 Nestin P48681 1 156668763-156677407 "Plasma proteins, Predicted intracellular proteins" Neurogenesis "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 161.6" "Group enriched" "Detected in many" 4 "Adipocytes: 102.2;Cardiomyocytes: 279.9;Endothelial cells: 105.5;Sertoli cells: 105.2;Smooth muscle cells: 70.5" "Cancer enhanced" "Detected in all" "glioma: 147.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 627.3;HUVEC TERT2: 321.5;LHCN-M2: 512.6;RH-30: 518.3;SuSa: 340.7;WM-115: 247.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005889, HPA006286, HPA007007, HPA026111, CAB058692" Enhanced Enhanced "Intermediate filaments" No No 100000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 12: NES - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Intermediate filaments" "CAB005889: AB_2251301, CAB058692: AB_2665584, HPA006286: AB_2667550, HPA007007: AB_1854381, HPA026111: AB_1854382" "unprognostic (7.73e-2)" "unprognostic (2.05e-1)" "unprognostic (2.80e-2)" "unprognostic (1.36e-1)" "unprognostic (6.37e-2)" "unprognostic (1.54e-1)" "unprognostic (1.08e-1)" "unprognostic (4.40e-2)" "unprognostic (7.56e-2)" "unprognostic (9.84e-2)" "unprognostic (4.49e-2)" "unprognostic (1.24e-1)" "prognostic unfavorable (8.02e-7)" "unprognostic (2.87e-1)" "unprognostic (2.48e-1)" "unprognostic (6.67e-2)" "unprognostic (8.11e-3)" 40.0 8.5 24.4 13.8 24.8 0.0 28.2 27.2 22.7 27.1 16.5 16.8 5.3 41.1 12.9 8.2 30.3 11.3 161.6 21.1 26.5 35.2 4.8 42.1 4.8 32.8 27.1 10.1 5.6 10.4 12.8 16.7 25.8 21.2 6.6 8.2 9.7 36.1 55.7 8.6 12.5 30.3 30.0 49.1 10.8 6.2 26.4 2.7 19.9 47.3 2.3 24.2 19.0 30.9 0.2 2.5 627.3 134.7 1.3 33.4 0.6 154.7 120.7 2.3 3.4 102.5 1.9 0.6 35.8 14.9 0.1 2.8 63.9 0.0 1.8 0.0 1.1 0.9 9.7 47.3 5.5 0.3 37.1 28.5 0.0 5.7 0.0 5.3 321.5 0.1 4.9 0.2 512.6 4.3 0.0 0.3 102.3 6.0 88.1 0.7 518.3 0.4 0.6 0.0 1.6 100.4 3.6 4.5 124.9 340.7 1.3 0.9 235.1 0.8 34.5 4.1 8.8 0.2 24.0 0.2 13.4 0.1 247.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.4 24.8 27.2 22.7 21.1 26.5 32.8 27.1 25.8 30.0 26.4 30.9 102.2 0.0 4.4 0.0 0.7 2.4 0.4 0.2 0.6 0.5 9.4 32.9 279.9 0.0 0.6 18.4 0.0 0.2 1.0 0.6 0.0 2.1 0.4 2.1 31.9 105.5 0.0 0.0 0.3 0.0 1.9 29.4 0.5 2.7 0.0 0.2 26.7 0.1 1.8 0.0 0.6 0.2 0.0 0.8 3.1 0.1 8.1 1.7 1.8 12.2 1.0 17.4 0.0 3.0 2.2 0.3 0.1 4.1 0.1 0.5 0.0 0.1 0.0 1.5 105.2 10.9 70.5 0.5 5.0 1.2 2.4 0.1 1.1 1.4 0.3 0.5 PJA2 "KIAA0438, Neurodap1, RNF131" ENSG00000198961 "Praja ring finger ubiquitin ligase 2" O43164 5 109334713-109409974 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040347, HPA057636" Supported Enhanced "Intermediate filaments" No No "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 43: Cardiomyocytes - Nuclear processes" "Intermediate filaments" "HPA040347: AB_10795631, HPA057636: AB_2683485" "unprognostic (5.78e-2)" "unprognostic (1.25e-1)" "unprognostic (5.48e-3)" "unprognostic (1.17e-1)" "unprognostic (2.99e-1)" "unprognostic (7.83e-2)" "unprognostic (2.83e-1)" "unprognostic (4.33e-2)" "unprognostic (4.84e-2)" "prognostic unfavorable (8.02e-4)" "unprognostic (4.46e-2)" "unprognostic (6.03e-2)" "unprognostic (5.64e-3)" "unprognostic (1.47e-3)" "unprognostic (5.94e-2)" "unprognostic (7.59e-2)" "unprognostic (1.00e-2)" 59.3 67.9 63.3 44.4 72.9 87.9 57.0 44.9 89.8 68.9 22.1 56.1 33.4 74.5 62.2 50.8 46.2 48.3 65.8 78.6 77.0 61.1 77.3 51.4 41.4 52.6 52.1 87.8 38.8 88.1 36.8 58.2 56.2 78.4 52.5 64.2 49.2 91.9 39.0 30.6 40.6 77.1 58.9 54.7 33.1 47.0 58.6 53.8 92.1 54.2 44.6 53.7 36.9 68.9 36.0 24.6 96.2 74.6 93.4 101.3 52.4 57.9 86.5 44.6 72.6 22.9 47.6 46.0 78.1 111.8 71.8 20.5 57.0 71.3 81.1 39.5 21.7 53.5 47.4 31.1 66.2 40.2 75.8 70.4 58.1 59.7 85.1 80.0 72.4 40.8 37.2 84.0 73.0 21.9 48.8 36.9 19.2 21.9 16.3 31.1 84.6 77.5 69.5 31.9 18.4 47.1 59.8 21.5 70.5 64.2 48.6 58.7 84.6 63.4 30.7 58.8 27.5 56.4 51.6 53.5 66.8 54.8 42.6 32.9 19.2 29.3 14.4 19.7 14.4 16.5 14.1 13.4 19.3 11.7 18.0 13.4 49.0 17.8 27.7 8.0 20.5 18.5 63.3 72.9 44.9 89.8 78.6 77.0 52.6 52.1 56.2 58.9 58.6 68.9 85.2 67.3 58.4 71.2 76.9 63.5 56.2 59.8 58.1 102.1 53.0 58.5 127.5 51.5 51.7 57.0 62.6 24.1 78.2 85.9 49.0 40.8 22.5 42.8 97.5 70.3 67.6 32.1 159.0 33.3 31.0 86.7 32.1 68.2 47.5 99.3 70.6 94.8 54.5 77.4 126.0 53.1 36.7 91.5 78.5 20.7 85.1 77.1 60.5 66.5 73.4 93.0 68.0 60.8 111.6 30.9 30.4 92.6 72.0 59.2 46.8 58.7 48.4 91.3 78.9 105.0 110.1 73.4 42.9 43.7 58.2 26.3 68.7 61.6 39.3 44.0 PKN2 "Pak-2, PRK2, PRKCL2, STK7" ENSG00000065243 "Protein kinase N2" Q16513 1 88684222-88836255 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell adhesion, Cell cycle, Cell division, Cilium biogenesis/degradation, Host-virus interaction, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 80.5" "Lineage enriched" "Detected in all" 8 "granulocytes: 80.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034861, HPA057913" Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Intermediate filaments,Centrosome,Cytosol" Yes No "Cluster 1: Neutrophils - Mixed function" "Cluster 34: Non-specific - Transcription" "Cluster 15: RT4 - Unknown function" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Intermediate filaments" "Nuclear bodies, Plasma membrane, Centrosome, Cytosol" "HPA034861: AB_2674363, HPA057913: AB_2732617" "unprognostic (7.52e-2)" "unprognostic (1.46e-1)" "prognostic favorable (5.67e-4)" "unprognostic (5.95e-2)" "unprognostic (3.39e-2)" "unprognostic (2.51e-2)" "unprognostic (4.64e-3)" "unprognostic (1.38e-1)" "unprognostic (4.43e-2)" "unprognostic (1.27e-2)" "unprognostic (2.90e-3)" "unprognostic (1.23e-1)" "unprognostic (1.51e-2)" "unprognostic (5.98e-2)" "unprognostic (2.38e-1)" "unprognostic (1.01e-2)" "unprognostic (1.99e-1)" 19.3 16.5 9.3 17.6 14.2 48.7 24.1 20.7 10.9 16.4 17.0 23.9 30.5 23.6 25.0 24.7 18.1 17.1 14.1 9.5 9.7 16.9 20.5 20.4 18.2 12.3 10.4 31.2 15.5 22.3 10.1 24.7 12.7 20.3 30.0 26.7 16.3 15.4 9.8 20.3 30.8 18.5 10.1 19.0 20.9 10.5 12.6 17.8 26.1 13.4 17.4 21.3 15.4 17.6 61.1 23.8 45.2 27.3 29.8 33.6 29.6 35.3 32.2 38.5 39.8 25.3 42.5 23.9 41.0 33.6 47.3 46.7 44.7 26.6 52.4 8.6 33.0 17.7 49.3 21.4 26.2 17.6 5.1 27.7 27.1 30.2 36.3 30.6 44.7 18.6 29.9 16.8 42.2 12.2 20.5 15.2 22.8 23.1 27.1 19.3 68.8 9.8 34.3 117.9 22.0 14.5 52.7 29.8 45.7 33.9 22.5 15.7 42.2 32.5 29.2 42.1 37.2 9.2 8.6 16.6 13.6 17.1 12.6 15.3 9.9 16.6 5.7 5.9 5.1 8.0 5.1 5.3 5.0 9.3 6.6 5.6 80.5 3.5 8.0 8.6 4.6 2.7 9.3 14.2 20.7 10.9 9.5 9.7 12.3 10.4 12.7 10.1 12.6 17.6 104.7 41.7 57.8 102.5 52.5 48.4 44.3 33.3 75.1 85.4 60.2 67.9 50.8 38.6 47.9 69.9 89.6 42.9 48.1 101.5 11.7 61.2 2.6 63.7 68.7 59.5 44.3 57.7 134.2 60.7 33.1 53.1 85.6 84.6 15.8 107.0 47.5 39.4 24.2 65.6 130.8 64.3 32.6 35.8 27.9 6.6 54.3 44.9 32.0 178.0 57.3 50.5 22.6 117.1 146.4 77.6 98.1 48.2 54.8 64.7 84.0 26.7 49.1 150.5 39.5 62.8 55.5 43.6 34.6 83.0 52.4 37.4 44.8 90.2 65.0 124.2 PLEC "EBS1, PCN, PLEC1, PLTN" ENSG00000178209 Plectin Q15149 8 143915153-143976734 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Cancer-related genes, Disease variant, Epidermolysis bullosa, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 256.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 257.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "PC-3: 384.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003847, HPA025967, HPA029906" Enhanced Supported "Intermediate filaments,Focal adhesion sites,Cytosol" NA NA 7400000 "Cluster 39: Non-specific - mRNA processing" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Intermediate filaments, Cytosol" "Focal adhesion sites" "CAB003847: AB_562198, HPA025967: AB_10601671, HPA029906: AB_10602279" "unprognostic (1.02e-1)" "unprognostic (1.37e-3)" "prognostic unfavorable (4.29e-4)" "unprognostic (2.09e-2)" "unprognostic (1.04e-1)" "unprognostic (1.05e-2)" "unprognostic (1.76e-3)" "prognostic unfavorable (5.33e-4)" "unprognostic (1.72e-3)" "unprognostic (1.13e-2)" "unprognostic (2.85e-3)" "unprognostic (5.48e-2)" "prognostic unfavorable (7.98e-6)" "unprognostic (2.30e-1)" "unprognostic (4.04e-2)" "unprognostic (6.58e-2)" "unprognostic (5.58e-3)" 41.8 30.9 44.2 22.6 25.4 43.2 37.9 20.4 39.7 57.4 6.7 58.0 21.1 55.2 8.5 59.7 47.9 22.8 78.9 42.2 31.0 30.0 31.3 49.2 22.1 48.5 28.6 47.1 27.6 8.1 33.0 18.3 30.8 49.5 13.0 3.9 42.9 19.8 256.5 83.1 53.8 27.7 28.8 46.1 49.1 15.3 43.2 14.4 25.7 74.7 15.8 56.5 55.7 25.9 92.6 247.3 15.1 20.3 31.6 66.9 62.8 125.9 49.3 32.3 18.7 39.2 88.5 8.9 82.9 179.7 54.6 98.9 10.3 162.6 13.3 58.7 10.0 24.9 268.0 34.0 54.0 9.6 26.1 71.8 40.7 84.6 164.2 28.3 43.0 7.6 16.2 25.9 39.7 175.3 5.1 19.8 12.2 29.4 384.8 1.8 46.2 24.6 67.7 147.7 16.6 16.8 217.4 50.0 21.1 21.7 55.7 12.4 125.7 117.8 217.3 110.6 155.1 4.7 3.7 6.3 106.9 15.2 176.2 0.0 2.0 0.1 0.6 1.7 1.3 0.6 1.2 0.9 1.6 0.6 0.8 0.5 0.4 0.3 1.2 1.3 1.4 2.0 44.2 25.4 20.4 39.7 42.2 31.0 48.5 28.6 30.8 28.8 43.2 25.9 83.8 28.9 15.6 78.0 27.0 108.0 53.1 62.9 50.7 15.8 29.4 27.9 39.3 31.5 42.9 40.5 25.0 34.4 27.1 257.8 0.0 39.3 1.4 39.4 52.6 68.2 32.2 11.8 47.3 20.2 32.1 45.7 170.2 57.3 8.2 14.4 63.1 69.0 35.2 30.3 36.5 79.9 10.2 67.5 100.4 5.0 44.4 61.2 33.8 27.2 54.9 11.2 15.5 14.6 3.4 157.8 194.1 74.9 39.3 144.9 124.9 4.6 50.3 10.8 6.6 42.1 61.5 1.2 7.1 72.2 76.7 69.0 35.0 18.8 61.6 121.0 PRKCE ENSG00000171132 "Protein kinase C epsilon" Q02156 2 45651345-46187990 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Cell adhesion, Cell cycle, Cell division, Immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 34.5" "Cell type enhanced" "Detected in many" "Early spermatids: 206.5;Excitatory neurons: 394.4;Inhibitory neurons: 531.9;Late spermatids: 456.4;Oligodendrocyte precursor cells: 147.8" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 18.5;basal ganglia: 20.0;cerebral cortex: 34.5;hippocampal formation: 33.1;white matter: 17.1" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "REH: 27.0;TIME: 26.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001948, HPA008236, HPA044496" Enhanced Supported Supported "Vesicles,Plasma membrane,Intermediate filaments,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 58: Brain - Synaptic function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Intermediate filaments, Cytosol" "Vesicles, Plasma membrane" "CAB001948: , HPA008236: , HPA044496: AB_2678959" "unprognostic (1.10e-1)" "unprognostic (1.78e-1)" "unprognostic (2.27e-1)" "prognostic unfavorable (2.42e-4)" "unprognostic (9.61e-2)" "unprognostic (5.70e-2)" "unprognostic (1.51e-1)" "prognostic favorable (9.62e-4)" "unprognostic (3.05e-1)" "unprognostic (6.72e-2)" "unprognostic (7.49e-3)" "unprognostic (9.99e-2)" "prognostic favorable (2.63e-7)" "unprognostic (1.21e-1)" "unprognostic (7.11e-2)" "unprognostic (6.43e-3)" "unprognostic (2.23e-2)" 4.4 5.6 18.5 3.7 20.0 8.0 4.2 5.5 34.5 4.6 0.0 5.7 2.6 4.4 2.3 4.1 5.7 3.0 6.2 33.1 0.0 10.0 12.5 20.1 5.7 6.0 0.2 2.8 3.3 9.4 5.2 8.3 4.4 2.9 3.3 15.4 2.7 3.0 7.6 2.7 3.5 4.1 0.0 3.9 4.1 7.6 1.1 3.1 4.9 5.3 4.2 4.9 3.4 17.1 7.7 2.7 3.8 3.8 5.8 6.7 3.1 4.9 9.5 4.3 4.5 0.7 7.0 11.3 4.8 5.5 6.1 1.8 2.5 2.8 6.1 6.9 4.4 0.1 1.8 1.5 6.5 0.9 3.8 5.8 3.0 6.5 4.7 3.6 16.0 2.4 1.6 2.6 5.0 3.8 3.8 0.5 1.3 4.2 1.4 27.0 18.3 12.4 3.9 5.1 2.6 5.7 2.4 7.6 17.1 1.4 6.1 2.6 26.8 8.2 8.5 6.1 5.1 0.0 0.0 9.3 6.7 6.3 8.4 0.0 0.5 0.7 0.3 0.1 0.4 1.5 0.2 0.2 0.8 1.8 0.5 0.1 0.1 0.4 0.6 0.3 0.0 0.3 18.5 20.0 5.5 34.5 33.1 0.0 6.0 0.2 4.4 0.0 1.1 17.1 12.6 6.4 9.2 90.4 20.7 5.0 8.4 5.0 9.1 55.3 6.4 5.7 11.9 8.6 17.2 11.0 14.6 0.5 9.3 6.1 3.9 3.7 206.5 6.8 7.0 13.8 7.7 0.4 394.4 3.8 7.2 8.7 11.2 6.9 7.0 2.9 13.2 12.5 2.8 11.8 531.9 5.8 0.0 19.0 10.7 456.4 5.3 11.5 14.2 70.3 9.4 6.5 1.0 147.8 96.0 3.6 2.9 6.0 4.2 5.3 4.1 30.2 19.3 7.6 13.1 2.9 6.4 2.8 2.3 9.0 4.8 2.9 6.8 1.2 6.2 8.8 PSMD10 p28 ENSG00000101843 "Proteasome 26S subunit, non-ATPase 10" O75832 X 108084207-108091549 "Predicted intracellular proteins" Apoptosis Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002920, CAB010434" Approved Supported "Intermediate filaments,Cytosol" NA NA 250000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 10: Non-specific - Unknown function" Cytosol "Intermediate filaments" "CAB010434: AB_640866, HPA002920: AB_1079708" "unprognostic (1.59e-3)" "unprognostic (4.12e-3)" "unprognostic (3.83e-1)" "unprognostic (3.00e-1)" "unprognostic (4.65e-2)" "unprognostic (1.50e-2)" "unprognostic (3.85e-3)" "unprognostic (2.35e-1)" "unprognostic (1.44e-1)" "unprognostic (2.06e-2)" "unprognostic (4.95e-2)" "unprognostic (7.37e-3)" "unprognostic (1.64e-2)" "unprognostic (1.42e-2)" "unprognostic (2.09e-1)" "unprognostic (5.07e-2)" "unprognostic (1.09e-1)" 28.2 38.6 49.4 26.2 52.3 28.7 35.1 54.5 68.3 34.3 47.4 32.7 25.3 36.4 48.3 34.5 44.9 25.8 26.0 49.9 58.9 34.6 33.4 28.6 34.8 55.4 58.6 31.7 18.6 41.4 33.1 40.4 61.4 31.6 33.2 44.6 26.2 30.4 24.8 26.8 27.0 36.2 56.4 27.1 27.8 27.5 57.5 41.9 38.1 23.9 39.1 33.4 27.7 59.4 101.3 100.5 68.9 62.6 102.6 77.3 61.8 81.6 69.2 73.9 64.0 60.7 64.4 86.0 119.7 80.2 107.6 54.0 109.8 80.3 113.4 91.3 94.8 50.5 91.0 78.2 51.8 79.2 54.8 58.2 85.9 67.2 82.2 73.2 186.4 83.2 99.9 114.3 94.0 133.0 75.3 70.9 124.1 96.9 138.3 74.2 97.5 92.7 80.7 64.8 44.2 42.1 124.8 52.4 86.0 87.4 56.5 66.9 130.5 58.1 33.1 98.3 61.4 88.5 128.5 90.5 80.4 109.2 69.7 83.6 46.8 72.3 45.9 58.1 49.0 47.9 45.8 49.2 52.2 48.0 45.6 51.4 22.0 58.3 71.4 53.0 57.8 69.9 49.4 52.3 54.5 68.3 49.9 58.9 55.4 58.6 61.4 56.4 57.5 59.4 14.2 19.2 19.8 3.3 23.4 22.6 25.9 31.8 23.9 15.1 20.4 20.6 11.2 8.6 35.4 11.0 2.1 28.3 12.8 16.5 31.3 19.9 4.1 38.3 26.9 22.8 14.4 35.7 3.4 18.7 35.3 22.6 11.7 21.6 34.1 17.9 22.1 25.6 31.3 13.5 4.5 16.8 16.2 29.5 19.0 4.4 25.7 20.2 17.8 0.0 26.1 18.3 20.6 5.5 9.6 24.5 14.1 21.1 34.7 26.6 14.9 34.8 69.9 7.7 0.0 13.8 32.1 46.2 40.3 32.4 29.1 25.0 20.2 24.6 19.2 33.7 S100A8 "60B8AG, CAGA, CFAG, CGLA, MRP8, P8" ENSG00000143546 "S100 calcium binding protein A8" P05109 1 153390032-153391073 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Autophagy, Chemotaxis, Immunity, Inflammatory response, Innate immunity" Antimicrobial "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 35382.0;esophagus: 24565.6;vagina: 11166.4" "Group enriched" "Detected in many" 7 "Basal respiratory cells: 4126.5;Kupffer cells: 6348.0;Macrophages: 3758.3;monocytes: 6932.6;Squamous epithelial cells: 8480.1" "Cancer enhanced" "Detected in all" "cervical cancer: 2290.9;head and neck cancer: 2382.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 9 "classical monocyte: 26833.7;neutrophil: 52973.6" "Group enriched" "Detected in all" 9 "granulocytes: 52973.6;monocytes: 26833.7" "Group enriched" "Detected in some" 24 "hTCEpi: 241.8;SK-BR-3: 719.0;THP-1: 400.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB002791, HPA024372" Enhanced Supported "Intermediate filaments,Cytosol" "Secreted to blood" NA NA 10900000 370000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Intermediate filaments" Cytosol "CAB002791: , HPA024372: AB_1856536" "unprognostic (1.98e-1)" "unprognostic (1.13e-1)" "unprognostic (3.79e-2)" "unprognostic (1.58e-2)" "unprognostic (8.60e-3)" "unprognostic (9.26e-3)" "unprognostic (4.92e-2)" "unprognostic (1.32e-1)" "unprognostic (1.83e-1)" "unprognostic (6.13e-2)" "unprognostic (3.77e-2)" "unprognostic (2.24e-2)" "prognostic unfavorable (8.94e-7)" "unprognostic (1.17e-1)" "unprognostic (8.90e-2)" "unprognostic (8.27e-2)" "unprognostic (8.94e-3)" 582.3 54.3 41.7 1245.8 45.6 35382.0 70.0 43.4 88.0 5650.6 45.5 55.2 15.4 23.1 5.5 24565.6 236.1 99.0 121.1 40.9 42.7 103.0 176.7 1061.7 29.5 47.7 44.8 25.8 52.0 9.6 41.7 205.8 50.7 43.1 14.7 5.6 3988.2 5.0 48.5 267.3 47.7 430.2 44.2 3239.5 93.8 16.2 45.5 281.3 48.8 174.8 8952.6 561.9 11166.4 46.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 9.0 1.3 0.0 0.3 12.4 0.0 18.7 0.0 0.1 0.0 3.5 0.0 0.0 0.0 5.6 0.1 0.0 241.8 0.0 7.5 0.0 0.0 0.0 9.6 1.2 0.0 0.9 0.4 1.5 0.3 0.0 0.0 0.4 5.8 1.0 0.0 0.0 0.4 0.5 3.6 719.0 0.0 0.0 4.7 400.6 10.6 0.0 0.2 0.9 0.1 0.2 1.3 2.7 0.3 13.9 0.0 848.0 26833.7 3023.7 33.4 1999.2 49.2 57.2 21.8 18.2 4686.1 23.5 21.6 23.3 52973.6 27.1 493.1 188.1 37.1 24979.9 41.7 45.6 43.4 88.0 40.9 42.7 47.7 44.8 50.7 44.2 45.5 46.2 1.1 224.4 489.8 0.0 77.2 19.6 3.5 4126.5 50.7 0.0 13.2 3.9 10.0 70.1 817.0 14.7 0.0 5.8 67.1 0.3 0.0 1.0 210.7 0.5 0.6 33.1 0.0 143.5 0.0 0.9 8.5 61.3 1.1 0.5 227.1 0.1 76.1 54.6 417.5 0.0 0.0 0.2 207.5 6348.0 5.1 172.4 4.1 3758.3 0.0 0.0 6932.6 0.0 289.4 0.0 0.0 1.4 0.0 1.5 26.1 0.9 0.0 25.0 162.8 0.0 0.0 7.7 32.3 2.1 1.0 8480.1 113.2 6.7 91.4 0.0 0.0 31.3 SESTD1 "DKFZp434O0515, Solo" ENSG00000187231 "SEC14 and spectrin domain containing 1" Q86VW0 2 179101678-179264832 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 175.5;Horizontal cells: 301.2;Oligodendrocytes: 311.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 45.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058236, HPA077408" Approved Enhanced "Intermediate filaments" NA Yes "Cluster 21: B-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 44: Endometrium - Transcription" "Intermediate filaments" "HPA058236: AB_2732619, HPA077408: AB_2732344" "unprognostic (2.76e-1)" "unprognostic (3.55e-2)" "unprognostic (2.77e-1)" "unprognostic (2.12e-1)" "unprognostic (1.78e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (1.88e-4)" "unprognostic (9.47e-2)" "unprognostic (1.64e-1)" "unprognostic (2.59e-1)" "unprognostic (7.91e-3)" "unprognostic (9.21e-2)" "prognostic favorable (2.78e-11)" "prognostic unfavorable (2.67e-4)" "unprognostic (3.25e-2)" "unprognostic (1.25e-1)" "unprognostic (2.57e-2)" 15.4 2.4 11.6 3.2 17.2 4.7 11.2 12.5 11.4 6.2 0.9 7.1 2.0 5.8 3.9 4.5 4.5 6.4 6.3 8.2 10.3 6.7 3.4 9.2 3.4 16.2 13.5 4.5 3.3 3.9 3.6 6.8 14.6 4.2 3.8 7.5 11.0 4.6 3.6 4.5 5.4 8.1 15.1 3.5 5.5 9.0 18.1 2.9 3.7 5.8 4.9 10.0 4.8 23.6 0.0 2.1 25.5 4.6 45.2 19.5 13.5 9.0 3.7 3.7 6.3 4.6 6.0 4.5 11.7 8.7 4.5 4.2 11.0 5.1 6.8 3.3 2.9 5.5 11.2 12.3 3.5 3.1 2.3 14.6 2.1 5.7 14.3 8.9 15.2 4.6 0.8 2.3 6.4 3.1 7.2 0.3 6.6 4.7 2.6 10.3 16.8 2.9 10.0 23.2 5.6 9.5 8.0 3.4 2.5 18.7 0.5 3.4 26.7 12.3 6.2 6.3 4.7 1.3 0.0 11.0 6.2 1.2 3.7 0.0 0.9 0.0 0.0 0.7 0.0 1.2 0.0 0.0 0.4 1.5 0.0 0.0 0.1 0.3 1.6 0.0 0.0 0.2 11.6 17.2 12.5 11.4 8.2 10.3 16.2 13.5 14.6 15.1 18.1 23.6 46.2 109.0 29.9 53.2 30.6 9.8 24.7 19.1 7.4 31.3 30.4 15.6 15.3 28.6 32.9 12.9 18.8 10.7 5.7 11.9 17.6 31.3 9.8 61.3 33.1 32.1 25.0 7.2 110.8 27.7 73.4 65.1 13.7 175.5 0.0 23.1 21.4 9.6 12.3 301.2 147.9 7.3 14.2 28.7 43.4 7.3 12.2 37.2 14.2 89.0 21.9 33.4 5.2 86.5 311.1 33.3 13.3 30.5 4.7 67.7 22.5 39.1 42.8 10.4 19.7 43.7 29.2 34.9 66.0 10.2 10.1 18.1 5.7 9.8 9.7 119.9 SYCE1L MRP2 ENSG00000205078 "Synaptonemal complex central element protein 1 like" A8MT33 16 77199408-77213215 "Predicted intracellular proteins" Meiosis "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 23.5" "Cell type enhanced" "Detected in many" "Breast glandular cells: 89.5;Breast myoepithelial cells: 125.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 11.1;U-698: 8.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA062464, HPA066691" Enhanced "Intermediate filaments" No No "Cluster 35: T-regs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 35: Glandular cells - Unknown function" "Intermediate filaments" "HPA062464: , HPA066691: AB_2685702" "unprognostic (5.54e-3)" "unprognostic (2.15e-1)" "unprognostic (1.65e-1)" "prognostic favorable (6.65e-4)" "unprognostic (1.32e-1)" "unprognostic (2.32e-1)" "unprognostic (3.48e-2)" "unprognostic (2.00e-3)" "unprognostic (6.28e-3)" "unprognostic (1.02e-1)" "unprognostic (7.48e-2)" "unprognostic (5.13e-2)" "prognostic unfavorable (2.11e-5)" "unprognostic (9.27e-2)" "unprognostic (4.27e-1)" "unprognostic (2.68e-2)" "unprognostic (1.73e-2)" 2.7 1.5 1.7 0.4 1.3 1.2 3.6 7.9 2.3 5.5 1.6 1.7 0.8 3.0 1.5 1.5 3.2 0.4 1.4 1.2 3.0 3.2 1.4 1.4 1.0 2.0 2.7 5.2 2.0 0.7 2.1 0.5 1.7 7.0 0.5 2.8 5.1 0.6 0.8 2.9 2.1 0.5 2.0 2.0 1.1 23.5 1.6 0.4 3.4 0.0 0.6 2.4 4.1 1.1 2.4 0.9 2.3 0.9 0.2 0.0 0.3 0.6 0.2 0.3 0.6 0.4 4.6 1.3 2.6 0.4 0.1 3.4 0.2 0.0 0.2 1.4 11.1 0.3 0.8 0.0 1.5 0.8 0.8 0.0 0.3 0.1 0.2 0.3 1.6 2.0 0.6 0.1 0.2 3.6 0.5 0.9 1.4 0.3 3.8 5.7 0.6 0.4 2.3 0.5 2.3 2.2 0.3 0.2 0.0 0.1 0.0 0.8 5.1 0.3 5.1 0.6 0.1 4.1 1.9 8.0 1.9 0.4 0.1 4.5 1.3 13.9 6.8 2.6 7.8 4.0 8.2 9.0 1.8 2.6 8.9 8.4 1.4 3.6 2.1 13.8 12.6 3.4 1.7 1.3 7.9 2.3 1.2 3.0 2.0 2.7 1.7 2.0 1.6 1.1 19.5 3.2 3.7 6.5 7.6 17.3 10.9 15.2 15.9 3.7 89.5 125.7 1.7 32.9 7.4 27.6 10.4 6.8 8.9 22.4 15.6 24.8 24.7 7.1 4.5 15.9 22.4 1.3 5.9 27.9 4.0 13.8 2.6 15.2 1.3 5.0 18.2 13.2 2.3 1.7 9.2 52.0 12.2 15.8 9.7 55.5 13.7 3.6 19.6 5.6 2.9 35.1 3.1 7.5 10.6 13.9 27.2 6.8 6.9 16.7 22.3 31.9 2.6 44.5 6.6 19.9 5.4 30.4 9.9 6.7 17.0 2.9 9.4 0.5 52.5 7.1 SYNM "DMN, KIAA0353, SYN" ENSG00000182253 Synemin O15061 15 99098217-99135593 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 594.1;skeletal muscle: 624.7;urinary bladder: 406.3" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 103.5;Cardiomyocytes: 502.5;Muller glia cells: 127.8;Smooth muscle cells: 98.5" "Cancer enhanced" "Detected in all" "prostate cancer: 28.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 36.8;HeLa: 58.0;WM-115: 124.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017192, HPA040066, HPA044200, HPA077856" Enhanced Supported "Intermediate filaments" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 17: WM-115 - Nervous system development" "Cluster 54: Cardiomyocytes - Muscle contraction" "Intermediate filaments" "CAB017192: , HPA040066: AB_2676830, HPA044200: AB_2678854, HPA077856: AB_2686861" "unprognostic (1.04e-2)" "unprognostic (1.37e-1)" "unprognostic (3.00e-2)" "unprognostic (6.10e-2)" "unprognostic (1.87e-1)" "unprognostic (1.15e-1)" "unprognostic (3.52e-2)" "unprognostic (1.10e-1)" "unprognostic (2.54e-1)" "unprognostic (1.00e-1)" "unprognostic (1.34e-2)" "unprognostic (6.75e-2)" "unprognostic (3.54e-3)" "unprognostic (2.80e-2)" "unprognostic (7.27e-2)" "unprognostic (5.92e-3)" "unprognostic (3.26e-3)" 37.2 20.3 51.4 26.5 66.0 0.4 56.7 70.1 58.2 11.8 52.5 594.1 27.1 50.8 12.7 169.6 36.5 19.2 144.2 44.4 75.4 6.9 4.8 23.1 4.2 81.7 66.6 14.1 6.3 8.2 23.2 14.0 81.6 150.6 52.0 40.3 25.6 291.3 624.7 17.0 105.7 160.9 71.6 2.9 158.4 5.2 69.3 3.7 11.2 277.1 4.0 406.3 41.0 79.8 6.6 36.8 8.1 21.9 15.9 0.9 0.5 3.7 5.3 2.1 1.3 5.4 4.9 0.0 5.3 5.3 17.7 4.2 5.5 0.1 1.6 0.5 9.0 0.1 58.0 5.4 9.0 0.0 1.0 0.9 0.3 3.7 0.8 6.0 4.3 0.0 0.2 7.4 5.5 3.7 0.7 0.8 7.2 0.7 11.4 0.0 7.5 5.5 2.1 3.6 3.6 4.2 21.9 3.4 13.5 12.7 0.2 3.6 4.8 4.1 0.4 2.9 8.9 0.1 1.0 0.0 0.4 0.0 124.5 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.3 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 51.4 66.0 70.1 58.2 44.4 75.4 81.7 66.6 81.6 71.6 69.3 79.8 14.8 0.0 1.7 15.3 0.9 2.3 0.7 0.9 2.8 12.6 32.7 103.5 502.5 0.0 1.2 0.0 16.7 1.5 6.6 2.1 0.0 0.5 9.5 1.3 1.0 24.2 3.0 0.0 15.6 1.3 0.7 20.3 5.1 4.2 0.0 1.1 3.6 1.3 0.3 42.1 9.8 0.9 0.0 0.0 5.1 4.5 1.2 2.0 5.4 12.2 0.6 127.8 1.0 2.5 14.0 0.2 2.3 4.1 5.4 2.0 0.6 0.3 3.1 10.2 32.9 19.6 98.5 7.9 11.5 2.1 3.7 0.4 5.9 0.2 0.7 0.9 TTC4 "CNS1, FLJ41930, MGC5097" ENSG00000243725 "Tetratricopeptide repeat domain 4" O95801 1 54715861-54742657 "Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041608, HPA042459" Approved Enhanced "Intermediate filaments,Cytoplasmic bodies" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Intermediate filaments" "Cytoplasmic bodies" "HPA041608: AB_10794485, HPA042459: AB_10797496" "unprognostic (4.89e-2)" "unprognostic (1.81e-1)" "unprognostic (2.05e-2)" "unprognostic (8.62e-4)" "unprognostic (8.91e-2)" "unprognostic (1.34e-1)" "unprognostic (1.21e-5)" "unprognostic (1.39e-4)" "unprognostic (1.51e-2)" "unprognostic (1.47e-1)" "unprognostic (3.18e-1)" "unprognostic (2.42e-3)" "unprognostic (7.12e-2)" "unprognostic (2.85e-1)" "unprognostic (7.79e-2)" "unprognostic (5.86e-2)" "unprognostic (1.76e-3)" 8.9 8.8 21.2 5.3 21.8 2.0 10.4 22.0 24.7 10.4 20.4 9.7 5.6 8.5 8.1 10.6 9.1 3.9 16.5 21.7 22.2 11.0 10.2 5.6 7.2 22.2 22.2 12.5 11.7 11.7 12.8 7.7 22.3 8.8 6.3 9.0 9.1 8.3 33.7 10.3 8.0 7.6 22.5 6.6 10.8 8.6 22.0 12.8 8.0 22.2 8.9 11.0 10.1 23.9 24.3 18.2 20.1 10.9 29.2 16.6 17.9 32.6 16.0 39.8 26.6 20.5 6.9 40.1 17.4 22.4 42.2 13.1 43.7 31.1 41.6 38.2 31.7 38.4 7.7 11.9 27.4 32.4 10.6 16.1 30.4 58.2 34.9 17.8 17.3 31.3 45.5 6.3 22.7 11.3 30.0 18.3 41.0 29.1 30.9 27.1 43.0 22.5 19.9 6.5 13.5 9.7 28.4 13.8 27.2 33.0 13.2 16.5 17.4 19.5 21.2 20.5 44.9 16.1 29.9 34.0 25.9 36.5 20.8 7.3 12.3 10.3 13.9 14.0 14.8 12.6 11.1 13.3 13.5 12.6 15.9 14.3 0.2 18.9 15.1 11.2 11.8 13.0 21.2 21.8 22.0 24.7 21.7 22.2 22.2 22.2 22.3 22.5 22.0 23.9 3.7 9.6 2.6 0.0 6.2 1.1 3.4 2.1 7.4 4.5 3.1 3.3 3.2 1.5 5.2 0.0 0.0 3.9 2.4 1.5 0.0 3.5 0.5 4.7 8.8 3.4 1.2 3.0 0.0 4.2 2.4 5.4 3.6 4.5 7.0 3.0 3.9 2.4 1.4 5.0 0.0 1.3 0.0 0.6 1.5 0.7 4.1 2.7 1.8 0.0 5.9 2.3 6.2 0.0 0.0 3.9 1.7 2.6 6.1 3.0 2.0 6.4 2.6 3.8 0.0 3.8 3.5 9.2 8.2 5.7 1.6 1.4 4.6 1.9 2.5 1.8 VIM ENSG00000026025 Vimentin P08670 10 17228241-17237593 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 4879.0;Langerhans cells: 4893.1;Leydig cells: 5013.2;Muller glia cells: 8977.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 18287.8;fHDF/TERT166: 10084.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000080, HPA001762, CAB058687" Enhanced Supported "Intermediate filaments" NA NA 35000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "Intermediate filaments" "CAB000080: AB_2304493, CAB058687: AB_2665570, HPA001762: AB_1080568" "unprognostic (1.02e-1)" "unprognostic (2.58e-1)" "unprognostic (2.87e-2)" "prognostic favorable (9.75e-6)" "unprognostic (3.81e-2)" "unprognostic (2.52e-1)" "unprognostic (3.21e-1)" "unprognostic (1.61e-1)" "unprognostic (1.17e-1)" "unprognostic (2.05e-1)" "unprognostic (9.29e-2)" "unprognostic (5.61e-2)" "prognostic unfavorable (8.69e-8)" "unprognostic (1.87e-3)" "unprognostic (7.32e-2)" "unprognostic (1.82e-1)" "unprognostic (9.47e-3)" 3467.6 423.1 349.3 610.6 369.5 1455.5 2362.8 289.1 527.4 1816.3 568.1 923.2 218.4 1226.5 400.0 451.5 1458.7 960.2 1364.3 337.5 404.6 473.6 192.8 1133.2 806.2 667.4 328.2 3690.8 370.0 224.8 574.5 1030.0 443.7 570.0 400.8 731.0 628.5 551.8 363.7 1126.8 674.7 1109.3 414.6 819.9 522.8 251.7 472.7 412.2 1391.1 555.8 744.7 983.5 1366.6 425.5 21.2 1119.0 1981.0 3180.7 6407.4 18287.8 3.0 5238.5 3458.9 3859.2 3421.5 8.5 70.4 2.9 273.2 10084.4 1804.7 8.4 283.8 147.0 3734.1 3567.5 387.2 563.2 523.5 0.3 1967.3 301.1 222.8 6746.8 6.5 5712.0 3213.4 9020.8 6366.3 372.4 889.3 1575.4 6939.5 4.5 736.6 911.2 632.4 1.4 1394.0 564.8 2745.9 95.7 3925.3 0.8 8.1 946.6 1.4 6.9 5447.5 1133.1 8.6 341.8 5459.0 3819.8 1644.5 3244.7 6311.5 1754.4 953.7 130.4 5775.4 28.9 3726.3 667.8 751.8 215.2 219.5 469.3 278.7 176.3 357.0 285.0 866.0 117.5 217.1 217.2 409.3 99.2 471.2 342.3 481.5 615.4 349.3 369.5 289.1 527.4 337.5 404.6 667.4 328.2 443.7 414.6 472.7 425.5 3211.7 157.0 349.4 53.5 605.8 725.8 21.6 361.2 58.1 74.2 108.8 539.1 109.5 94.4 157.3 108.5 50.1 22.1 1110.1 9.1 5.9 198.8 58.1 922.9 2314.1 2923.2 309.1 236.5 0.4 569.0 45.8 3443.0 101.4 693.7 2776.4 4879.0 2195.6 19.2 3541.4 33.7 0.3 1.8 16.2 2841.2 4893.1 131.6 5013.2 3177.8 3082.5 85.3 3893.1 8977.0 259.5 1.0 0.4 525.9 1.5 2336.6 2097.2 79.5 3.1 181.6 90.7 284.1 1420.0 3171.9 3714.2 55.1 27.5 39.4 473.0 52.7 1566.3 1791.1 6.2 28.9 ZNF131 "pHZ-10, ZBTB35" ENSG00000172262 "Zinc finger protein 131" P52739 5 43065176-43192021 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007023, HPA027748, HPA074630" Approved Enhanced "Nucleoplasm,Intermediate filaments" No No "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 20: HeLa - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "Intermediate filaments" "HPA007023: AB_2667726, HPA027748: AB_2672374, HPA074630: AB_2686705" "unprognostic (1.23e-1)" "unprognostic (8.24e-2)" "unprognostic (4.70e-2)" "unprognostic (7.97e-2)" "unprognostic (8.84e-2)" "unprognostic (7.18e-2)" "prognostic unfavorable (1.56e-4)" "unprognostic (2.52e-1)" "unprognostic (2.98e-3)" "unprognostic (1.94e-2)" "unprognostic (5.83e-2)" "unprognostic (8.07e-2)" "unprognostic (2.09e-2)" "unprognostic (1.47e-2)" "unprognostic (2.76e-1)" "unprognostic (3.11e-3)" "unprognostic (1.46e-2)" 13.2 13.5 12.5 13.9 12.8 28.4 19.5 17.3 21.7 13.8 10.0 13.2 10.0 17.6 9.6 14.4 12.6 12.9 9.6 12.8 12.4 12.0 14.3 11.4 20.3 11.4 11.9 15.9 12.2 11.7 10.7 16.9 11.9 12.6 13.2 14.7 10.4 9.0 15.8 18.2 12.0 15.9 11.3 15.9 11.6 32.6 12.3 26.7 11.8 17.1 17.5 15.0 13.3 14.2 25.4 15.2 32.4 43.2 30.1 20.6 27.3 32.8 26.6 31.9 26.9 24.0 22.2 50.8 25.9 22.1 29.7 17.7 38.9 20.8 44.9 24.8 34.1 31.4 92.2 18.0 27.7 55.0 24.7 18.8 38.2 23.5 38.3 22.8 24.7 39.0 40.7 52.7 36.8 24.5 53.9 68.8 21.5 23.4 24.9 35.3 49.4 39.9 27.1 24.4 20.0 29.4 83.5 39.8 43.2 21.7 22.3 51.6 18.5 39.8 37.3 20.5 31.1 21.1 32.5 58.4 21.0 71.2 27.1 10.4 8.2 5.8 19.1 9.5 19.2 13.1 18.5 18.5 11.9 16.8 22.3 18.3 3.9 17.2 6.6 11.3 14.9 10.0 12.5 12.8 17.3 21.7 12.8 12.4 11.4 11.9 11.9 11.3 12.3 14.2 42.5 22.4 21.9 28.7 44.7 49.6 51.4 24.1 53.5 52.1 32.3 29.7 17.5 22.8 19.4 9.2 52.1 27.0 53.3 28.0 31.3 15.3 52.9 30.0 47.7 32.8 31.2 39.1 31.2 11.8 25.0 32.4 23.0 49.7 24.1 39.4 24.7 13.3 16.4 38.7 33.6 29.7 20.3 25.8 35.4 19.5 20.5 30.9 21.4 14.0 27.5 29.0 49.4 38.7 24.2 17.9 24.7 21.1 27.8 38.5 34.9 13.1 15.7 70.0 26.3 57.0 43.2 109.6 80.3 45.9 65.5 25.4 59.3 37.3 38.7 35.6 ZNF774 MGC75360 ENSG00000196391 "Zinc finger protein 774" Q6NX45 15 90352284-90369146 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 15.4;Granulosa cells: 45.3;Spermatocytes: 11.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HeLa: 9.0" "HPA030839, HPA030840" Uncertain Supported "Intermediate filaments,Cytosol" No No "Cluster 11: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" "Intermediate filaments" Cytosol "HPA030839: AB_2673630, HPA030840: AB_10602691" "unprognostic (1.11e-1)" "unprognostic (2.14e-1)" "unprognostic (1.38e-1)" "unprognostic (5.82e-3)" "unprognostic (3.29e-2)" "unprognostic (1.35e-1)" "unprognostic (6.89e-2)" "unprognostic (9.22e-3)" "unprognostic (7.82e-2)" "unprognostic (1.94e-1)" "unprognostic (3.43e-1)" "unprognostic (2.89e-2)" "unprognostic (2.71e-1)" "unprognostic (5.62e-2)" "unprognostic (1.27e-1)" "unprognostic (4.48e-2)" "unprognostic (4.82e-2)" 0.7 2.7 2.3 1.2 4.2 1.0 3.4 4.3 3.6 2.6 0.0 4.6 2.2 2.8 4.1 1.4 3.0 2.9 2.8 1.9 2.6 1.4 1.1 1.1 0.7 0.7 1.0 1.1 3.9 3.1 3.0 0.7 0.8 2.4 7.1 4.0 3.9 5.7 6.2 3.1 2.0 1.8 0.0 0.6 2.6 2.2 2.7 1.5 2.7 7.2 0.9 1.9 1.6 3.3 1.7 0.7 2.1 2.4 0.9 0.5 5.0 1.0 1.7 1.3 1.6 2.7 2.0 0.6 2.0 1.3 3.7 2.5 2.2 3.7 1.3 1.2 4.2 1.8 9.0 1.3 1.6 1.0 1.3 0.5 4.4 1.9 1.8 3.6 2.3 3.4 2.0 0.8 2.1 1.6 1.4 0.9 0.6 4.5 2.5 1.3 1.8 0.5 2.6 4.6 4.8 2.0 2.0 3.1 0.8 2.4 2.1 0.2 1.1 1.4 1.3 1.1 2.2 5.2 3.8 0.4 2.3 2.8 0.7 1.4 0.3 0.7 0.2 0.1 0.1 0.2 0.2 0.3 0.6 0.4 0.2 0.2 1.2 0.7 0.2 0.3 0.1 0.1 2.3 4.2 4.3 3.6 1.9 2.6 0.7 1.0 0.8 0.0 2.7 3.3 0.6 6.4 3.2 0.3 0.7 0.8 2.5 1.0 2.2 6.4 2.4 2.4 4.9 0.0 1.1 0.0 0.0 1.7 0.2 6.8 1.9 2.8 15.4 1.7 2.3 1.0 2.4 0.0 2.5 2.0 1.1 0.9 4.1 3.2 0.0 45.3 0.0 1.5 0.8 8.4 2.3 3.3 0.0 0.3 0.7 11.0 0.3 0.8 0.0 0.0 0.2 2.0 0.0 1.5 1.1 1.7 5.5 2.2 0.7 1.4 1.9 1.1 0.7 5.3 0.0 1.7 1.9 11.8 4.5 1.3 0.3 1.4 0.5 0.3 5.5 2.0