Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" AC213203.1 ENSG00000268674 P0DMU3 Unmapped 35407-35916 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Tissue enriched" "Detected in single" 5 "brain: 1.8" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 1.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043267, HPA043292, HPA077864" Uncertain Approved "Intermediate filaments" NA NA "Cluster 21: B-cells - Adaptive immune response" "Intermediate filaments" "HPA043267: , HPA043292: , HPA077864: AB_2686862" 0.0 0.0 0.2 0.0 0.1 0.0 0.0 1.8 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 1.8 0.3 0.1 0.2 0.3 0.2 0.1 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 BICDL2 CCDC64B ENSG00000162069 "BICD family like cargo adaptor 2" A1A5D9 16 3027682-3036944 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 104.8;pancreas: 127.2" "Cell type enhanced" "Detected in some" "Breast glandular cells: 52.2;Breast myoepithelial cells: 22.1;Ductal cells: 34.3;Endometrial ciliated cells: 28.9;Exocrine glandular cells: 49.8;Glandular and luminal cells: 28.3;Pancreatic endocrine cells: 35.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 9.0;BEWO: 15.4;CAPAN-2: 14.4;HaCaT: 22.5;MCF7: 22.8;RT4: 10.8;SK-BR-3: 11.0;T-47d: 14.0" "Not detected" "Not detected" "Region enhanced" "Detected in single" "basal ganglia: 2.7" HPA043251 Approved Approved "Intermediate filaments,Actin filaments,Cytosol" No NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 30: Mammary glandular cells - Lactation" "Intermediate filaments, Actin filaments, Cytosol" "HPA043251: AB_10794925" "unprognostic (2.00e-1)" "unprognostic (5.37e-2)" "unprognostic (1.71e-1)" "unprognostic (6.06e-3)" "unprognostic (9.65e-5)" "unprognostic (5.79e-3)" "unprognostic (6.47e-2)" "unprognostic (1.75e-2)" "unprognostic (2.45e-1)" "unprognostic (1.66e-2)" "unprognostic (2.05e-2)" "unprognostic (4.71e-2)" "unprognostic (8.56e-2)" "unprognostic (2.55e-2)" "unprognostic (2.38e-1)" "unprognostic (4.32e-2)" "prognostic favorable (9.04e-4)" 0.4 0.0 0.2 1.9 0.2 0.0 8.6 0.4 0.4 20.7 0.1 25.1 10.4 0.7 2.6 104.8 6.0 3.4 0.0 0.2 0.1 5.8 0.9 5.9 0.0 0.6 0.3 0.1 127.2 4.1 1.5 0.3 0.8 16.8 6.4 0.0 44.4 3.2 0.6 43.8 13.5 0.2 0.2 0.2 21.5 0.1 0.3 0.2 6.1 0.0 3.1 11.4 44.3 0.2 9.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 2.6 14.4 0.0 0.0 0.0 0.0 22.5 0.0 0.4 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.8 0.0 0.1 0.0 6.4 0.0 0.1 0.0 0.2 0.0 10.8 0.2 0.1 0.0 11.0 0.0 0.3 14.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.4 0.4 0.2 0.1 0.6 0.3 0.8 0.2 0.3 0.2 0.3 12.8 18.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 52.2 22.1 0.0 0.0 12.4 16.5 0.0 4.5 1.3 0.0 3.9 34.3 0.0 28.9 2.8 0.5 0.0 0.0 0.0 49.8 6.1 0.6 0.0 28.3 2.5 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 35.8 0.0 0.0 0.1 0.0 0.0 0.2 12.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 4.5 0.6 0.3 0.0 0.0 C12orf54 MGC35033 ENSG00000177627 "Chromosome 12 open reading frame 54" Q6X4T0 12 48482498-48496524 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 39 "testis: 40.4" "Cell type enriched" "Detected in many" 4 "Late spermatids: 2541.6" "Cancer enhanced" "Detected in some" "cervical cancer: 2.9;head and neck cancer: 2.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HBEC3-KT: 2.7" "Not detected" "Not detected" HPA073090 Approved "Intermediate filaments" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" "Intermediate filaments" "HPA073090: " "unprognostic (2.59e-3)" "unprognostic (5.49e-2)" "unprognostic (7.94e-3)" "unprognostic (2.60e-2)" "unprognostic (2.48e-2)" "unprognostic (8.99e-2)" "unprognostic (5.96e-2)" "unprognostic (1.62e-1)" "unprognostic (8.01e-2)" "unprognostic (1.36e-4)" "unprognostic (2.37e-1)" "unprognostic (5.06e-3)" "unprognostic (7.53e-2)" "unprognostic (1.34e-1)" "unprognostic (1.97e-1)" "unprognostic (1.92e-1)" 0.0 0.4 0.3 0.0 0.4 0.0 0.2 0.2 1.0 0.1 0.0 0.1 0.0 0.2 0.0 0.4 0.1 0.1 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.5 0.4 0.5 0.0 0.0 0.0 0.1 0.5 0.2 0.1 0.2 0.0 0.3 0.0 0.1 0.0 0.3 0.3 0.1 0.0 40.4 0.3 0.0 0.0 0.2 0.6 0.2 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.2 1.0 0.3 0.2 0.5 0.4 0.5 0.3 0.3 0.5 0.0 0.0 2.6 8.1 0.0 5.1 38.6 19.5 1.2 0.2 0.2 0.1 0.7 0.0 4.5 0.0 0.0 0.1 0.0 0.0 1.9 0.1 543.1 0.0 0.0 1.2 0.0 0.0 5.3 0.0 0.2 0.4 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 9.1 0.0 2.0 0.0 1.8 2541.6 10.8 1.4 0.0 2.8 0.0 0.3 0.0 4.5 2.5 0.0 0.0 13.2 0.0 6.4 0.0 1.9 1.9 0.2 6.6 4.3 1.0 11.5 6.5 5.9 2.3 0.0 0.5 0.4 0.0 10.8 C19orf25 FLJ36666 ENSG00000119559 "Chromosome 19 open reading frame 25" Q9UFG5 19 1461143-1479219 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050270, HPA067491" Approved Approved "Intermediate filaments" No No "Cluster 31: Non-specific - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" "Intermediate filaments" "HPA050270: AB_2681069, HPA067491: AB_2685849" "unprognostic (5.82e-2)" "unprognostic (3.87e-2)" "unprognostic (6.51e-2)" "prognostic favorable (1.08e-4)" "unprognostic (1.74e-1)" "unprognostic (2.14e-3)" "prognostic unfavorable (3.81e-4)" "unprognostic (1.10e-2)" "unprognostic (1.36e-1)" "unprognostic (2.49e-2)" "prognostic favorable (1.21e-4)" "unprognostic (5.35e-2)" "prognostic favorable (9.20e-8)" "unprognostic (3.50e-3)" "unprognostic (8.01e-2)" "unprognostic (1.82e-1)" "unprognostic (1.91e-3)" 14.4 23.5 33.3 8.8 33.2 7.8 15.9 31.1 43.8 17.7 29.3 18.0 15.6 15.8 5.3 20.4 15.7 8.1 21.2 31.6 30.0 31.0 29.5 14.8 15.0 35.3 33.1 15.9 19.9 15.6 27.1 8.6 32.0 22.1 5.2 6.9 17.6 8.1 16.2 17.3 17.7 6.1 32.7 23.4 17.8 22.0 34.0 9.7 23.8 7.4 7.0 17.5 15.6 36.7 25.0 19.2 11.6 18.3 11.0 10.0 23.4 24.4 16.8 25.5 23.5 27.4 12.1 14.2 18.7 13.0 12.1 30.1 17.9 15.0 6.0 44.7 27.1 17.3 12.2 32.3 23.6 27.5 33.5 9.2 33.2 10.7 17.2 18.3 13.2 29.3 46.1 32.7 16.6 13.9 25.6 21.8 36.2 15.2 29.5 41.4 16.0 36.5 17.8 16.7 19.8 26.5 18.0 23.0 28.5 6.0 33.4 31.8 16.3 19.8 22.4 40.6 23.4 46.3 26.7 24.2 20.4 27.4 35.1 50.1 32.1 59.1 41.3 33.0 33.5 36.6 37.9 35.7 23.4 45.6 38.2 30.9 52.0 30.5 27.7 47.6 52.6 38.6 33.3 33.2 31.1 43.8 31.6 30.0 35.3 33.1 32.0 32.7 34.0 36.7 24.2 16.0 8.7 10.4 44.3 19.2 30.5 27.3 18.8 62.7 28.9 29.7 10.3 21.5 19.9 51.5 64.6 41.5 45.2 68.1 49.0 40.1 6.2 14.7 21.0 23.0 50.6 17.2 14.5 46.1 33.3 21.7 31.1 19.3 11.4 30.4 29.3 18.2 35.9 97.6 11.5 33.7 34.6 27.9 24.9 7.3 26.4 26.4 24.9 8.4 56.7 49.2 82.4 14.1 20.6 52.6 52.0 21.8 26.7 33.5 83.2 35.5 15.3 87.8 46.0 20.0 24.1 33.8 33.0 14.8 19.7 52.9 47.3 36.1 38.2 33.6 C19orf54 FLJ41131 ENSG00000188493 "Chromosome 19 open reading frame 54" Q5BKX5 19 40740856-40751553 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 17.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059043, HPA059628" Approved Approved "Intermediate filaments,Centriolar satellite" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 20: HeLa - Mitochondria" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Intermediate filaments" "Centriolar satellite" "HPA059043: AB_2683886, HPA059628: AB_2684087" "unprognostic (3.18e-3)" "unprognostic (2.09e-2)" "unprognostic (5.19e-2)" "unprognostic (7.21e-2)" "unprognostic (8.44e-2)" "unprognostic (1.22e-1)" "unprognostic (1.32e-2)" "unprognostic (2.97e-1)" "unprognostic (1.98e-2)" "unprognostic (2.25e-1)" "unprognostic (3.00e-2)" "unprognostic (3.16e-1)" "unprognostic (2.70e-1)" "unprognostic (1.50e-1)" "unprognostic (1.33e-1)" "unprognostic (1.03e-2)" "unprognostic (6.33e-2)" 5.8 10.1 6.2 6.9 7.7 6.0 5.8 7.3 6.6 4.7 6.8 8.1 10.5 5.1 6.4 6.0 4.9 6.2 7.2 6.1 6.0 9.1 15.3 8.8 5.5 8.4 7.3 3.8 8.6 5.7 4.6 4.8 7.7 6.2 7.1 5.3 5.6 4.5 15.3 5.9 10.7 4.0 6.8 9.8 7.5 8.4 7.1 5.5 7.8 10.3 6.0 6.3 5.0 8.7 7.6 16.6 13.9 12.4 7.4 10.0 10.2 5.4 7.0 9.5 8.9 11.3 11.3 16.5 13.6 6.4 4.7 12.0 23.0 9.2 7.8 11.5 20.7 10.3 24.4 14.3 22.5 7.1 8.8 15.2 4.8 9.3 19.9 11.7 5.7 22.1 13.3 22.8 6.7 9.0 10.0 8.2 10.5 17.4 6.0 18.9 14.2 14.3 9.6 14.5 11.3 7.0 19.5 8.1 8.4 15.3 8.4 9.6 4.8 11.7 11.7 6.1 3.7 25.6 18.9 13.0 11.3 15.4 8.3 0.4 4.5 1.3 1.3 3.8 0.5 1.2 1.1 0.7 5.7 0.9 1.1 1.0 1.0 0.8 5.1 3.5 1.9 1.9 6.2 7.7 7.3 6.6 6.1 6.0 8.4 7.3 7.7 6.8 7.1 8.7 2.9 3.2 8.9 6.2 2.9 1.7 3.7 3.3 5.2 1.6 4.2 3.0 8.0 2.8 1.2 5.5 2.1 7.9 2.5 5.5 3.9 3.4 6.7 3.3 3.7 3.5 1.2 4.6 0.4 2.5 6.6 2.3 7.7 3.1 0.0 4.1 1.8 6.4 8.4 0.0 0.7 5.0 4.1 10.7 1.6 2.9 2.5 7.2 0.0 1.0 8.2 2.2 1.0 1.5 3.4 2.0 4.8 1.2 5.4 2.4 12.3 6.7 2.9 3.8 0.0 1.9 2.3 17.8 12.0 4.4 1.7 5.6 2.8 6.1 5.5 2.8 C1orf159 FLJ20584 ENSG00000131591 "Chromosome 1 open reading frame 159" Q96HA4 1 1081818-1116361 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 22.9" "Cell type enhanced" "Detected in many" "Early spermatids: 60.9;Late spermatids: 124.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010019, HPA075399" Approved Approved "Nucleoli rim,Mitotic chromosome,Intermediate filaments" Yes No "Cluster 34: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoli rim, Mitotic chromosome" "Intermediate filaments" "HPA010019: AB_1078885, HPA075399: " "unprognostic (2.79e-1)" "unprognostic (9.46e-2)" "unprognostic (5.43e-2)" "unprognostic (1.16e-1)" "unprognostic (2.12e-1)" "unprognostic (2.60e-3)" "prognostic unfavorable (9.58e-6)" "unprognostic (1.34e-1)" "unprognostic (3.09e-1)" "unprognostic (2.04e-2)" "unprognostic (9.29e-2)" "unprognostic (3.26e-3)" "prognostic unfavorable (1.77e-6)" "unprognostic (4.10e-2)" "unprognostic (1.81e-1)" "unprognostic (7.56e-2)" "prognostic favorable (1.62e-4)" 4.0 4.8 9.6 1.6 8.0 2.4 3.8 0.9 10.4 5.3 3.2 6.1 1.8 4.2 1.1 8.6 4.8 2.2 4.3 9.4 1.0 7.7 6.7 3.9 1.8 6.3 2.7 4.3 3.7 0.7 5.3 1.4 2.8 6.9 0.6 1.6 4.6 2.3 2.2 5.0 4.1 0.5 0.7 5.5 6.0 22.9 5.4 1.8 4.5 0.3 0.9 5.5 5.9 6.9 15.7 12.0 5.6 10.0 1.5 1.6 13.3 9.0 2.1 7.8 5.1 6.5 14.7 4.3 10.8 2.8 6.4 12.2 2.5 7.1 2.2 8.6 18.2 3.1 19.6 7.0 3.6 5.5 7.3 3.2 2.8 3.3 1.6 2.3 3.8 6.4 18.6 3.1 2.8 11.9 10.2 13.2 4.7 5.9 19.7 12.0 6.7 8.5 4.7 4.7 11.8 16.1 6.8 12.2 7.6 1.6 7.8 6.5 5.2 8.3 8.8 11.9 9.2 5.6 8.3 7.8 6.8 14.9 6.5 8.1 2.6 1.4 2.6 2.6 2.8 2.5 2.5 3.0 1.7 2.2 2.5 2.6 0.5 2.7 1.8 2.2 0.9 2.3 9.6 8.0 0.9 10.4 9.4 1.0 6.3 2.7 2.8 0.7 5.4 6.9 6.3 0.0 7.7 20.2 3.4 7.5 3.6 6.2 4.6 5.9 8.9 6.6 2.3 5.7 7.1 9.2 4.2 5.0 4.9 13.6 1.9 8.2 60.9 8.6 8.2 4.4 4.2 5.2 26.5 7.0 14.0 4.2 20.4 9.0 5.7 9.0 3.3 5.3 3.9 13.5 21.8 7.4 6.1 1.0 4.8 124.1 2.8 3.9 3.6 2.8 6.0 3.2 9.2 10.6 24.5 7.8 3.5 1.5 6.9 5.1 3.4 1.8 10.4 8.2 0.0 3.5 4.8 18.3 6.8 4.2 7.0 4.9 4.6 4.4 9.4 4.9 C6orf52 ENSG00000137434 "Chromosome 6 open reading frame 52" Q5T4I8 6 10671418-10694797 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "testis: 13.7" "Cell type enhanced" "Detected in many" "Early spermatids: 46.4;Endometrial ciliated cells: 44.9;Late spermatids: 27.3;Respiratory ciliated cells: 37.7;Spermatocytes: 36.1;Spermatogonia: 20.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 3.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "NB-4: 6.1;U-266/84: 6.4" "Not detected" "Not detected" HPA051142 Uncertain Approved "Nuclear speckles,Intermediate filaments" No No "Cluster 35: T-regs - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" "Nuclear speckles" "Intermediate filaments" "HPA051142: AB_2681359" "unprognostic (1.14e-2)" "unprognostic (2.21e-2)" "unprognostic (1.63e-1)" "prognostic favorable (6.50e-5)" "unprognostic (9.12e-2)" "unprognostic (2.96e-1)" "unprognostic (1.11e-3)" "unprognostic (1.67e-1)" "unprognostic (1.03e-1)" "unprognostic (2.23e-2)" "unprognostic (2.02e-1)" "unprognostic (1.17e-1)" "unprognostic (1.46e-2)" "unprognostic (2.17e-2)" "unprognostic (3.92e-2)" "unprognostic (9.31e-3)" "unprognostic (7.65e-2)" 1.0 1.8 2.2 0.5 2.2 0.3 1.1 2.3 4.0 0.7 3.1 0.8 3.3 0.5 3.5 0.6 3.3 0.2 0.6 2.2 2.5 4.4 0.7 1.0 0.4 2.6 2.7 1.1 2.2 0.3 2.0 0.2 2.6 2.0 0.3 0.8 0.8 0.5 0.5 1.3 0.7 0.3 2.4 0.7 1.6 13.7 2.3 0.5 0.8 0.2 0.6 0.6 0.5 2.8 1.0 2.0 1.8 1.7 0.6 0.0 3.3 0.3 0.0 0.2 0.4 2.7 1.6 0.2 2.9 0.0 2.8 0.2 1.8 0.0 0.6 1.2 4.5 0.8 0.5 0.5 0.0 1.2 0.5 0.3 2.6 0.7 1.0 0.4 0.0 1.9 3.6 0.3 0.7 6.1 1.5 6.1 1.9 1.4 2.3 1.3 0.4 0.9 0.8 0.5 3.8 2.1 0.8 0.5 3.9 2.3 0.2 1.0 0.7 1.4 0.5 1.0 1.4 2.6 6.4 1.4 2.3 0.9 1.6 0.0 0.2 2.4 0.6 0.5 0.2 0.2 0.7 0.6 0.5 0.3 0.3 0.3 0.3 0.7 0.3 0.4 3.1 0.3 2.2 2.2 2.3 4.0 2.2 2.5 2.6 2.7 2.6 2.4 2.3 2.8 0.7 0.0 2.7 3.3 1.2 1.5 2.0 4.2 0.0 1.6 3.2 3.7 1.3 1.5 2.6 3.7 2.1 2.9 0.2 1.6 5.9 4.1 46.4 44.9 0.9 1.9 3.0 0.0 0.9 6.1 2.3 1.1 2.0 2.5 0.0 0.6 1.4 1.9 1.2 1.7 1.0 1.2 0.0 0.3 1.0 27.3 2.1 0.6 3.6 0.0 1.6 3.3 1.0 0.0 3.5 2.8 2.7 0.0 2.5 2.0 1.3 9.6 37.7 0.9 0.0 1.1 2.1 36.1 20.4 0.6 1.4 1.4 0.4 0.4 1.7 1.0 CARD10 "BIMP1, CARMA3" ENSG00000100065 "Caspase recruitment domain family member 10" Q9BWT7 22 37490362-37519542 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 35.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 35.5;Ductal cells: 25.4;Endothelial cells: 24.8;Pancreatic endocrine cells: 39.4;Paneth cells: 27.6;Proximal enterocytes: 35.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 56.5;U-2197: 82.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029359, HPA055612" Approved Approved "Vesicles,Intermediate filaments,Cytosol" No No "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Vesicles, Intermediate filaments" Cytosol "HPA029359: AB_10601354, HPA055612: AB_2682861" "unprognostic (9.12e-3)" "unprognostic (2.28e-1)" "unprognostic (7.51e-2)" "prognostic favorable (3.47e-4)" "unprognostic (4.54e-1)" "unprognostic (2.70e-2)" "prognostic unfavorable (7.73e-6)" "unprognostic (3.66e-2)" "unprognostic (7.70e-2)" "unprognostic (1.93e-1)" "unprognostic (2.16e-1)" "unprognostic (3.68e-2)" "unprognostic (2.78e-2)" "unprognostic (2.87e-2)" "unprognostic (4.34e-1)" "unprognostic (4.31e-2)" "unprognostic (9.69e-2)" 10.0 8.4 3.7 5.0 3.3 0.1 10.5 2.9 4.0 6.5 2.8 13.3 34.1 6.0 1.3 8.4 7.5 7.8 10.7 3.1 3.0 14.9 12.4 6.1 2.1 4.7 3.3 3.1 9.2 2.7 2.1 4.7 5.0 5.4 8.8 0.3 19.0 4.2 8.0 9.7 35.9 4.2 3.3 4.1 9.9 15.0 4.2 0.8 6.8 8.2 1.0 6.1 5.8 2.9 31.3 23.1 4.1 3.0 0.1 8.7 19.6 2.8 6.5 12.8 10.0 14.2 21.8 0.0 10.8 5.4 12.4 43.0 4.9 56.5 3.9 0.1 11.8 0.7 15.6 22.1 5.4 0.5 1.9 2.9 11.5 24.5 31.2 10.2 26.1 0.0 3.3 0.0 9.9 11.0 0.1 2.0 7.2 17.0 13.2 0.0 38.9 3.0 19.1 5.4 1.5 2.4 21.0 9.5 2.1 5.0 10.1 1.7 35.0 9.5 26.9 82.8 16.4 0.1 0.0 0.0 30.2 0.0 21.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 3.3 2.9 4.0 3.1 3.0 4.7 3.3 5.0 3.3 4.2 2.9 22.6 0.0 2.0 0.0 0.2 8.5 6.8 3.4 2.2 1.2 3.9 4.3 3.7 10.0 1.6 3.7 0.0 0.4 0.2 35.5 1.9 25.4 7.8 3.3 0.4 24.8 7.7 0.0 0.1 19.6 1.6 1.9 15.8 6.2 0.0 0.4 17.9 4.8 0.1 0.0 0.6 19.8 4.1 0.0 1.2 8.6 0.0 0.4 5.4 3.7 0.0 0.0 0.0 0.0 0.1 39.4 27.6 0.7 0.2 8.6 35.5 12.4 1.2 0.2 0.0 6.2 1.1 0.4 3.4 2.5 3.8 0.0 0.6 1.0 11.3 9.7 CDC42BPA "FLJ23347, KIAA0451, MRCK, MRCKA, PK428" ENSG00000143776 "CDC42 binding protein kinase alpha" Q5VT25 1 226989865-227318474 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 320.3;Excitatory neurons: 447.6;Inhibitory neurons: 479.0;Oligodendrocyte precursor cells: 444.3;Oligodendrocytes: 671.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB070414, HPA071252" Approved Approved "Intermediate filaments" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Intermediate filaments" "CAB070414: AB_11156796, HPA071252: AB_2686374" "unprognostic (3.67e-3)" "unprognostic (1.45e-1)" "unprognostic (1.10e-1)" "unprognostic (2.78e-2)" "unprognostic (3.04e-1)" "unprognostic (5.90e-2)" "unprognostic (7.89e-2)" "unprognostic (2.27e-1)" "unprognostic (1.46e-1)" "unprognostic (3.93e-1)" "unprognostic (4.88e-2)" "unprognostic (2.87e-2)" "unprognostic (7.73e-3)" "unprognostic (1.35e-1)" "unprognostic (1.70e-1)" "unprognostic (9.79e-2)" "unprognostic (1.21e-2)" 15.6 12.5 26.3 5.5 32.4 3.5 12.2 33.5 30.0 15.8 12.2 21.2 14.7 15.0 7.7 10.1 12.6 13.7 16.4 24.9 25.2 17.3 14.7 12.3 2.0 25.7 26.8 14.0 13.1 19.7 14.6 12.7 27.0 15.8 10.3 23.7 7.6 14.9 11.4 6.3 12.9 14.5 19.8 6.6 22.4 24.4 29.7 2.2 8.1 13.6 1.8 23.0 11.3 37.0 22.6 21.1 21.9 10.4 21.5 26.4 7.7 25.4 35.7 17.2 17.9 17.1 50.1 0.1 26.6 42.4 13.0 10.3 16.3 14.2 20.9 0.1 13.2 17.4 25.5 6.7 24.3 14.1 7.5 18.6 17.9 27.8 27.8 21.3 58.0 13.6 45.1 0.1 28.2 6.2 0.4 2.5 18.0 29.3 20.0 0.0 37.0 0.1 27.7 43.1 15.7 22.9 43.0 17.8 24.8 13.4 23.1 0.8 59.0 31.3 16.2 36.1 33.9 0.1 0.1 0.1 41.4 0.0 42.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 26.3 32.4 33.5 30.0 24.9 25.2 25.7 26.8 27.0 19.8 29.7 37.0 82.6 41.7 35.7 320.3 0.8 11.7 26.0 15.9 12.0 97.7 14.0 12.8 59.9 30.0 38.9 44.1 118.9 5.9 1.8 49.3 13.7 26.0 128.0 18.7 45.1 68.4 26.4 45.6 447.6 41.1 7.3 44.4 92.8 25.7 7.0 21.5 47.8 28.9 3.7 223.8 479.0 30.5 22.4 4.4 9.9 132.3 44.1 6.4 16.0 180.8 5.9 33.4 0.0 444.3 671.8 65.1 74.0 85.4 1.8 30.1 50.7 41.3 24.8 66.9 78.9 64.0 68.4 45.6 57.7 8.0 8.0 1.4 1.3 23.4 34.4 43.1 CHID1 "FLJ42707, MGC3234, SI-CLP" ENSG00000177830 "Chitinase domain containing 1" Q9BWS9 11 867859-915058 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 404.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039374 Uncertain Uncertain "Nucleoplasm,Intermediate filaments" "Intracellular and membrane" No No 1500000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Intermediate filaments" "HPA039374: AB_10673609" "unprognostic (1.85e-1)" "unprognostic (2.19e-1)" "unprognostic (8.96e-2)" "prognostic favorable (6.76e-4)" "unprognostic (4.82e-2)" "unprognostic (3.22e-1)" "unprognostic (1.97e-2)" "unprognostic (3.62e-2)" "unprognostic (7.88e-2)" "unprognostic (2.29e-1)" "unprognostic (1.12e-2)" "unprognostic (5.21e-2)" "unprognostic (1.74e-3)" "unprognostic (1.15e-1)" "unprognostic (7.53e-2)" "unprognostic (3.29e-2)" "unprognostic (2.89e-2)" 43.9 63.3 43.1 22.7 44.1 46.2 40.2 41.0 51.7 44.5 60.0 34.2 30.9 38.0 89.5 34.8 63.5 41.3 54.4 44.1 47.2 52.5 85.8 30.9 27.2 42.9 42.9 58.0 149.9 46.1 62.8 42.7 42.5 42.3 29.7 25.2 82.2 41.3 37.0 34.9 27.7 35.7 42.6 71.6 47.1 74.1 45.7 20.1 47.3 31.1 20.2 34.3 35.3 47.0 75.6 71.7 53.2 131.6 203.3 107.5 90.1 83.2 97.0 78.8 76.7 78.7 214.6 61.1 75.1 121.7 78.4 145.2 53.1 95.9 57.3 53.7 131.9 44.1 25.9 75.1 92.6 102.9 37.4 104.1 59.2 53.9 77.2 130.3 67.2 76.6 81.2 152.6 55.8 52.9 58.4 134.0 47.2 141.6 107.3 49.0 50.9 111.8 57.5 21.5 101.8 84.5 90.3 124.0 78.4 53.0 50.4 156.8 66.6 89.6 38.9 25.3 68.3 88.9 81.4 36.0 100.2 88.6 71.7 21.1 50.4 19.2 34.7 45.0 37.1 45.7 33.2 36.8 74.0 32.1 34.9 35.3 6.2 43.4 45.6 69.6 32.4 46.0 43.1 44.1 41.0 51.7 44.1 47.2 42.9 42.9 42.5 42.6 45.7 47.0 33.0 41.7 36.7 4.2 28.6 22.8 62.2 78.9 22.2 38.5 69.9 75.7 25.6 51.5 49.0 53.3 18.8 121.3 34.4 25.2 72.4 62.3 120.9 44.0 44.4 31.5 53.3 56.4 7.8 58.3 79.7 69.6 20.9 36.8 29.2 107.6 50.0 91.2 81.1 30.3 7.8 42.8 57.0 66.6 24.7 404.8 62.7 34.0 55.2 1.9 35.2 60.6 20.6 6.0 6.8 38.0 43.2 58.3 123.7 86.5 71.5 85.1 45.7 53.2 52.6 45.9 41.7 208.3 139.9 37.2 23.3 91.5 19.2 85.4 59.9 62.6 DDX60 FLJ20035 ENSG00000137628 "DExD/H-box helicase 60" Q8IY21 4 168216291-168318883 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "stomach 1: 40.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 57.6;Gastric mucus-secreting cells: 90.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 27.4;BJ hTERT+ SV40 Large T+ RasG12V: 26.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA046952 Approved Supported "Intermediate filaments,Cytosol" No No "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 4: Stomach - Digestion" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "Intermediate filaments" "HPA046952: AB_10963572" "unprognostic (4.05e-2)" "unprognostic (2.87e-1)" "unprognostic (7.22e-3)" "unprognostic (7.71e-2)" "unprognostic (2.30e-1)" "unprognostic (2.65e-2)" "unprognostic (1.50e-2)" "unprognostic (3.15e-2)" "unprognostic (3.06e-1)" "unprognostic (8.69e-3)" "prognostic unfavorable (3.35e-4)" "unprognostic (1.65e-1)" "unprognostic (4.03e-2)" "unprognostic (2.48e-1)" "unprognostic (3.02e-1)" "unprognostic (3.20e-2)" "unprognostic (2.44e-1)" 8.2 6.0 2.3 9.8 2.6 5.6 7.2 2.0 2.4 9.6 2.6 17.4 13.3 7.7 4.8 3.5 7.1 9.7 5.9 1.9 2.4 6.7 9.4 11.4 9.8 4.8 2.3 11.0 4.0 6.4 4.0 11.5 2.9 6.0 15.7 3.3 21.3 5.8 2.4 6.5 12.3 6.1 5.1 17.4 40.8 3.4 3.2 15.4 6.3 3.5 6.8 6.8 5.6 3.1 8.3 1.1 4.2 1.4 2.9 10.4 5.3 2.3 14.9 27.4 26.1 0.0 20.2 0.0 1.4 3.1 12.6 6.6 0.5 4.1 8.7 6.1 0.3 12.9 7.3 0.0 9.9 3.8 3.3 7.2 1.7 6.7 1.2 7.1 10.1 4.8 0.0 2.0 3.4 0.3 6.2 2.5 0.4 0.4 2.1 5.1 1.5 0.0 5.3 4.6 0.8 0.7 5.4 1.3 18.8 0.3 1.0 5.1 8.9 2.1 1.5 0.9 2.0 1.6 0.3 0.0 6.6 6.1 6.1 1.6 1.2 1.2 4.2 2.5 4.8 1.4 3.2 4.1 1.1 1.4 3.3 3.7 0.6 3.7 3.0 0.0 3.0 1.8 2.3 2.6 2.0 2.4 1.9 2.4 4.8 2.3 2.9 5.1 3.2 3.1 32.4 35.3 6.5 14.0 12.2 4.2 4.8 6.2 5.7 0.8 3.9 3.2 8.6 11.5 11.5 12.9 0.0 7.6 13.4 57.6 5.9 8.2 3.3 11.8 10.5 22.8 3.0 8.4 0.7 6.8 10.4 11.6 90.2 10.2 27.3 16.2 14.3 4.0 6.2 0.0 1.3 22.4 2.0 4.1 2.8 2.2 8.1 13.5 3.6 25.3 9.3 7.4 17.5 27.6 1.3 12.0 14.9 9.4 3.1 4.1 11.0 4.2 15.3 2.9 6.6 10.0 9.0 1.1 1.0 2.2 2.7 2.9 17.2 18.4 6.0 3.7 DISC1 ENSG00000162946 "DISC1 scaffold protein" Q9NRI5 1 231626790-232041272 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Neurogenesis, Wnt signaling pathway" "Developmental protein" Schizophrenia "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 21.7" "Cell type enriched" "Detected in many" 4 "Rod photoreceptor cells: 113.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "THP-1: 11.4;TIME: 8.7;WM-115: 8.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA048911 Supported "Intermediate filaments,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 43: THP-1 - Innate immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Intermediate filaments, Cytosol" "HPA048911: AB_2732549" "unprognostic (1.08e-1)" "unprognostic (1.40e-1)" "unprognostic (1.58e-1)" "unprognostic (2.98e-1)" "unprognostic (2.57e-2)" "unprognostic (3.36e-2)" "unprognostic (6.69e-3)" "unprognostic (1.41e-1)" "unprognostic (9.49e-2)" "unprognostic (1.71e-1)" "unprognostic (8.89e-2)" "unprognostic (9.53e-2)" "unprognostic (1.31e-4)" "unprognostic (1.74e-2)" "unprognostic (2.02e-1)" "unprognostic (5.94e-2)" "unprognostic (1.94e-1)" 2.4 1.4 5.3 3.1 5.4 2.6 1.9 3.9 5.6 2.1 2.6 1.5 1.1 1.5 0.5 1.3 1.1 2.6 9.0 4.2 4.9 1.1 1.4 1.7 2.4 6.9 5.8 4.4 0.8 1.1 1.0 7.3 6.9 1.2 1.2 21.7 2.0 0.9 1.4 1.2 1.3 1.4 5.6 2.9 1.0 0.9 7.3 3.1 1.8 1.1 1.7 1.6 1.3 7.7 0.0 0.4 4.0 0.1 0.1 0.3 2.8 1.6 3.6 4.1 3.5 1.4 0.8 0.1 4.8 1.3 1.0 0.0 0.3 0.1 3.7 2.6 1.7 2.2 0.3 4.0 0.5 3.7 5.1 2.2 0.7 1.4 1.2 2.8 3.8 2.7 0.0 1.4 4.6 0.4 1.1 5.6 2.0 0.0 1.5 2.7 1.1 0.4 0.1 0.0 0.7 2.2 1.4 0.0 2.4 1.0 0.0 11.4 8.7 2.1 2.3 1.0 0.9 0.9 0.7 0.0 1.7 5.6 8.8 0.1 0.8 0.0 0.2 0.8 0.1 0.0 0.4 0.0 1.0 0.1 0.4 0.1 0.7 0.2 0.4 0.6 0.1 0.2 5.3 5.4 3.9 5.6 4.2 4.9 6.9 5.8 6.9 5.6 7.3 7.7 6.7 0.0 1.1 0.0 2.1 0.9 0.5 0.7 3.4 23.3 2.0 1.8 7.2 0.0 1.2 3.7 8.4 8.0 2.0 0.5 0.0 0.6 16.6 3.4 2.1 6.7 0.0 2.1 0.0 1.1 0.8 3.0 0.0 4.5 7.0 8.0 10.0 0.0 11.3 0.0 0.0 0.1 0.0 13.0 12.6 23.2 0.9 13.7 3.6 0.0 5.6 2.4 2.1 0.0 0.0 2.0 0.3 1.5 2.1 0.7 0.0 0.2 2.5 113.1 0.0 4.6 2.7 1.4 1.6 0.5 1.1 2.5 5.8 8.1 0.7 0.6 DMRTC1 ENSG00000269502 "DMRT like family C1" Q5HYR2 X 72872025-72943814 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 2.5;pituitary gland: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046874, HPA046992" Uncertain Approved "Nucleoplasm,Intermediate filaments" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Intermediate filaments" "HPA046874: AB_2679850, HPA046992: AB_2679894" "unprognostic (1.83e-1)" 0.0 0.5 1.5 0.1 1.3 0.0 0.0 0.0 2.5 0.3 0.0 0.1 0.0 0.4 0.0 0.1 0.7 0.2 0.0 1.0 1.8 0.1 0.0 0.1 0.3 0.4 0.2 0.5 0.2 0.2 1.8 0.0 0.5 0.1 0.2 0.8 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.4 0.1 0.6 1.3 0.2 0.7 0.0 0.3 0.1 0.1 2.4 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.3 0.0 2.5 1.0 1.8 0.4 0.2 0.5 0.0 1.3 2.4 0.0 0.0 0.5 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 DMRTC1B ENSG00000184911 "DMRT like family C1B" Q5HYR2 X 72777009-72848802 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 22.5;pituitary gland: 25.3" "Cell type enhanced" "Detected in some" "Excitatory neurons: 1.3;Microglial cells: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046874, HPA046992" Uncertain Approved "Nucleoplasm,Intermediate filaments" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Intermediate filaments" "HPA046874: AB_2679850, HPA046992: AB_2679894" "unprognostic (2.00e-1)" "unprognostic (1.91e-2)" "unprognostic (1.54e-1)" "unprognostic (6.52e-2)" 0.2 3.2 17.5 0.8 17.9 0.0 0.6 11.6 22.5 1.1 10.7 1.0 0.4 1.6 6.7 0.2 2.3 0.4 0.2 18.7 19.7 1.4 0.0 0.8 1.0 13.7 14.3 8.2 3.8 1.5 25.3 0.0 13.7 2.7 0.5 9.7 0.8 1.2 0.0 0.3 1.0 0.4 11.9 1.0 1.0 8.9 20.5 1.2 3.3 0.0 1.5 0.3 0.8 16.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.5 0.5 0.8 0.0 0.0 0.0 0.0 0.0 0.0 17.5 17.9 11.6 22.5 18.7 19.7 13.7 14.3 13.7 11.9 20.5 16.5 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 FAM174B "LOC400451, MGC102891" ENSG00000185442 "Family with sequence similarity 174 member B" Q3ZCQ3 15 92617448-92809884 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 76.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 105.8;Intestinal goblet cells: 60.9;Late spermatids: 57.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 8.9" "Group enriched" "Detected in many" 7 "dendritic cells: 3.5;granulocytes: 2.9;T-cells: 8.9" "Cell line enhanced" "Detected in many" "CACO-2: 74.3;MCF7: 91.8;OE19: 76.3;RPMI-8226: 109.6;RT4: 221.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015306 Approved Approved "Intermediate filaments" No No "Cluster 4: T-regs - Cell cycle regulation" "Cluster 25: Pancreas - Digestion" "Cluster 15: RT4 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" "Intermediate filaments" "HPA015306: AB_2669182" "unprognostic (3.00e-3)" "unprognostic (1.80e-1)" "unprognostic (1.50e-1)" "prognostic favorable (9.03e-5)" "unprognostic (4.68e-2)" "unprognostic (1.63e-1)" "unprognostic (8.35e-2)" "unprognostic (8.23e-3)" "unprognostic (7.67e-3)" "unprognostic (5.05e-3)" "unprognostic (6.60e-2)" "unprognostic (1.33e-1)" "unprognostic (4.67e-2)" "unprognostic (2.01e-1)" "unprognostic (6.64e-2)" "unprognostic (1.61e-2)" "unprognostic (2.35e-2)" 5.6 5.6 13.8 5.9 13.2 1.1 27.2 9.7 14.6 16.9 9.1 10.7 6.3 8.2 7.2 8.4 24.0 6.1 10.5 13.9 14.5 5.3 6.9 21.0 8.5 14.0 16.0 16.2 76.6 2.9 26.5 6.7 14.6 32.2 15.2 6.4 52.5 16.2 16.2 8.4 8.5 4.9 7.8 4.0 35.0 17.9 14.9 8.0 37.2 15.9 7.4 26.3 6.6 19.5 0.3 12.2 8.0 2.4 0.0 0.2 1.0 4.6 21.8 0.2 0.0 74.3 8.6 1.2 20.6 0.6 5.8 0.4 13.9 0.5 0.0 0.5 6.5 0.7 1.4 1.0 1.3 1.1 3.2 1.0 0.3 0.2 0.2 0.5 10.5 6.8 1.2 54.7 12.2 91.8 2.7 0.1 39.2 76.3 0.0 8.9 22.5 109.6 5.4 221.3 4.9 3.9 6.4 42.7 14.3 22.7 33.8 7.9 0.0 0.0 1.6 0.3 10.3 1.7 17.2 2.6 0.2 0.8 5.3 0.9 0.6 0.8 0.1 0.7 0.2 0.3 1.8 0.0 0.5 0.3 2.0 2.6 2.9 0.7 0.0 3.5 8.9 0.6 13.8 13.2 9.7 14.6 13.9 14.5 14.0 16.0 14.6 7.8 14.9 19.5 8.5 105.8 22.2 13.7 1.7 2.3 14.7 1.7 5.7 7.0 26.3 11.3 5.2 5.7 12.6 7.3 8.4 1.4 2.3 3.7 7.9 5.5 22.6 17.8 4.2 10.3 42.1 0.8 24.0 14.6 21.2 4.9 19.4 23.4 18.4 1.3 22.1 7.0 5.4 11.8 24.4 60.9 24.4 3.8 4.8 57.8 5.9 4.9 12.4 22.5 0.4 3.9 0.0 17.1 44.8 19.1 1.6 1.9 6.6 24.2 3.0 1.5 14.5 3.7 0.0 7.7 3.7 1.0 5.0 3.9 3.0 0.7 3.4 1.8 5.5 24.3 GFAP FLJ45472 ENSG00000131095 "Glial fibrillary acidic protein" P14136 17 44903159-44916937 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 13076.3" "Cell type enriched" "Detected in some" 7 "Astrocytes: 381.9" "Cancer enriched" "Detected in some" 368 "glioma: 2468.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 6.2" "Group enriched" "Detected in many" 5 "granulocytes: 6.2;NK-cells: 1.7" "Cell line enhanced" "Detected in many" "U-87 MG: 6.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000039, HPA056030, HPA063513" Enhanced Supported Supported "Intermediate filaments" No No 170000000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 70: Brain - Nervous system development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 64: Astrocytes - Nervous system maintenance" "Intermediate filaments" "CAB000039: AB_10013382, HPA056030: AB_2683015, HPA063513: AB_2685027" "unprognostic (1.79e-2)" "unprognostic (2.74e-1)" "unprognostic (9.83e-2)" "unprognostic (2.12e-5)" "unprognostic (4.08e-1)" "unprognostic (5.09e-1)" "unprognostic (1.26e-1)" "unprognostic (6.53e-2)" "unprognostic (6.57e-3)" "unprognostic (7.35e-2)" "unprognostic (5.86e-2)" "unprognostic (1.24e-1)" "unprognostic (7.63e-2)" "unprognostic (2.75e-5)" "unprognostic (1.49e-1)" "unprognostic (1.66e-1)" "unprognostic (1.64e-1)" 1.9 1.8 5096.2 2.2 5407.4 14.1 3.5 5902.8 4887.4 1.9 2342.2 1.4 0.4 0.9 1.5 3.7 2.2 1.6 8.2 5059.3 9869.7 2.1 1.7 1.3 1.9 13076.3 9001.4 2.1 1.5 1.6 33.9 0.7 9204.1 1.3 1.0 117.7 1.9 1.0 2.1 2.6 0.7 0.9 10040.2 1.5 1.5 1.4 8068.5 0.4 1.7 0.3 1.1 1.4 0.9 10496.9 1.0 0.7 1.2 2.3 0.0 0.4 0.2 1.0 1.2 1.5 1.2 1.3 1.5 2.2 1.9 0.5 0.9 2.7 1.4 0.4 1.8 3.0 1.1 1.4 2.1 0.9 0.0 0.2 2.2 0.1 0.8 1.0 0.0 1.7 0.0 2.3 0.7 5.3 0.8 1.3 1.9 2.6 1.6 0.1 3.3 0.7 0.7 1.2 0.7 0.6 1.6 1.8 0.1 1.7 0.2 1.0 1.2 1.2 0.7 1.2 0.9 1.1 2.0 0.7 1.6 1.6 6.1 2.0 2.7 1.5 0.8 0.3 0.3 0.6 0.2 0.2 0.2 0.4 0.1 0.5 0.3 0.4 6.2 1.7 0.5 0.5 0.2 0.2 5096.2 5407.4 5902.8 4887.4 5059.3 9869.7 13076.3 9001.4 9204.1 10040.2 8068.5 10496.9 0.0 0.0 0.0 381.9 0.1 0.0 0.1 0.0 0.0 0.8 1.3 0.6 5.2 0.0 0.0 0.0 6.2 0.0 0.1 0.0 0.0 0.3 0.1 0.1 0.1 0.8 0.0 0.0 0.5 0.2 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 3.7 0.0 53.5 0.0 10.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 4.4 0.0 0.2 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 HOXA13 "HOX1, HOX1J" ENSG00000106031 "Homeobox A13" P31271 7 27193503-27200091 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 23.1;placenta: 17.1;prostate: 22.3;seminal vesicle: 23.3" "Cell type enriched" "Detected in some" 4 "Distal enterocytes: 41.3" "Cancer enhanced" "Detected in many" "prostate cancer: 10.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 26.9;HEK 293: 37.3;PC-3: 18.4;RT4: 42.1;THP-1: 18.2;U-937: 20.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046098, HPA069061" Supported "Nucleoplasm,Mitotic chromosome,Intermediate filaments" Yes NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Mitotic chromosome, Intermediate filaments" "HPA046098: AB_2679536, HPA069061: " "unprognostic (7.20e-2)" "unprognostic (1.89e-1)" "unprognostic (1.02e-1)" "unprognostic (8.04e-4)" "unprognostic (1.06e-3)" "unprognostic (2.24e-2)" "unprognostic (1.79e-1)" "unprognostic (1.40e-2)" "unprognostic (9.22e-3)" "unprognostic (7.30e-3)" "unprognostic (8.39e-3)" "unprognostic (1.54e-1)" "unprognostic (1.42e-11)" "unprognostic (2.58e-3)" "unprognostic (1.38e-1)" "unprognostic (1.72e-1)" "unprognostic (1.36e-2)" 0.6 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 23.1 0.0 9.9 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.1 0.0 22.3 11.9 0.0 0.0 23.3 2.1 0.3 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.1 14.1 0.0 2.2 1.6 0.0 2.5 0.2 0.0 0.1 13.2 14.4 5.1 3.3 2.8 0.2 0.0 1.6 6.2 0.7 0.0 26.9 0.0 4.3 0.0 37.3 1.9 6.9 0.2 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.2 0.1 0.0 8.7 0.0 11.8 18.4 2.7 0.6 0.0 0.1 42.1 0.7 0.0 3.3 0.0 0.3 2.0 0.0 18.2 0.0 0.5 4.5 0.3 0.1 0.0 0.0 0.0 0.0 20.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 41.3 0.0 0.0 0.6 0.1 4.0 1.1 8.4 0.0 0.0 0.0 0.1 2.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.6 0.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 5.5 0.0 0.1 0.0 0.0 0.0 0.1 2.8 0.5 0.0 0.0 0.1 0.1 0.1 0.0 10.3 3.1 HSDL1 SDR12C3 ENSG00000103160 "Hydroxysteroid dehydrogenase like 1" Q3SXM5 16 84122141-84145192 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 45.4;Rod photoreceptor cells: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045745 Supported "Vesicles,Intermediate filaments,Mitochondria" No No "Cluster 34: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "Vesicles, Intermediate filaments" "HPA045745: AB_2679440" "unprognostic (2.16e-1)" "unprognostic (4.32e-2)" "unprognostic (2.09e-1)" "unprognostic (4.80e-3)" "unprognostic (3.66e-2)" "unprognostic (1.68e-1)" "prognostic unfavorable (3.50e-4)" "unprognostic (1.25e-2)" "unprognostic (7.43e-2)" "unprognostic (3.39e-2)" "unprognostic (6.42e-2)" "unprognostic (3.66e-1)" "prognostic favorable (4.20e-7)" "unprognostic (2.30e-1)" "unprognostic (1.57e-1)" "unprognostic (1.03e-2)" "unprognostic (1.14e-2)" 7.5 15.4 14.3 7.1 14.6 4.4 11.9 10.9 13.0 10.6 10.7 7.4 6.2 13.2 10.5 7.8 12.6 7.1 15.7 14.0 18.3 10.8 5.1 9.1 9.0 15.0 14.8 22.0 4.9 15.1 11.9 9.1 18.6 9.8 6.9 34.3 7.3 11.1 20.7 8.0 5.7 10.8 9.5 8.0 6.4 13.2 17.0 14.1 26.8 30.5 9.2 7.3 7.1 10.2 11.1 12.6 57.4 19.8 20.7 14.5 14.6 13.8 13.1 17.0 8.9 14.5 18.8 22.7 24.7 12.4 18.8 7.6 31.1 12.1 26.9 4.9 18.9 10.9 7.9 32.5 21.0 17.1 19.2 11.0 20.0 24.1 15.4 21.9 20.9 30.6 23.0 28.2 34.3 27.3 37.8 17.4 29.5 6.4 13.3 36.7 20.4 8.4 16.6 12.0 27.1 20.2 35.0 5.6 39.0 28.5 34.4 10.2 17.5 19.2 22.9 13.9 11.3 44.1 38.1 36.9 22.8 12.3 18.2 21.2 5.0 11.1 3.8 3.4 5.0 5.0 4.1 4.6 2.8 7.5 5.3 5.6 5.5 4.3 6.3 0.0 5.4 4.4 14.3 14.6 10.9 13.0 14.0 18.3 15.0 14.8 18.6 9.5 17.0 10.2 8.9 12.8 16.4 7.8 8.2 4.8 4.6 6.4 8.6 20.2 10.2 8.3 16.7 1.5 8.6 3.7 14.6 6.9 4.4 3.7 5.9 7.9 38.5 11.4 10.5 7.7 9.5 5.7 12.4 6.7 6.6 7.7 3.6 11.0 1.3 38.6 9.3 4.1 12.2 45.4 15.8 3.7 4.1 6.9 3.5 12.2 5.9 10.4 5.4 11.2 6.1 28.4 5.2 15.6 13.0 6.8 2.5 10.1 10.1 5.2 3.9 8.0 13.7 44.2 0.0 8.0 7.8 35.8 30.1 8.8 7.0 8.8 6.6 12.7 4.5 4.8 IQUB FLJ35834 ENSG00000164675 "IQ motif and ubiquitin domain containing" Q8NA54 7 123452193-123535077 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 33.4" "Group enriched" "Detected in many" 7 "Early spermatids: 283.9;Endometrial ciliated cells: 82.6;Late spermatids: 157.5;Respiratory ciliated cells: 88.2;Spermatocytes: 116.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RPTEC TERT1: 2.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA049626 Approved "Nucleoplasm,Nuclear speckles,Intermediate filaments,Cytosol" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" "Nuclear speckles" "Nucleoplasm, Intermediate filaments, Cytosol" "HPA049626: AB_2732554" "unprognostic (8.71e-2)" "unprognostic (1.25e-2)" "unprognostic (1.98e-1)" "unprognostic (6.42e-4)" "unprognostic (1.91e-1)" "unprognostic (1.44e-2)" "unprognostic (6.23e-2)" "unprognostic (7.97e-2)" "unprognostic (1.46e-1)" "unprognostic (1.73e-1)" "unprognostic (2.40e-2)" "unprognostic (3.76e-1)" "unprognostic (5.44e-6)" "unprognostic (2.79e-1)" "unprognostic (9.78e-3)" "unprognostic (2.14e-1)" "unprognostic (7.30e-2)" 0.1 0.6 0.2 0.0 0.4 0.0 0.5 1.7 0.9 0.8 3.9 0.1 0.0 0.7 1.1 0.0 5.0 0.8 0.1 0.2 0.5 3.0 0.0 0.8 0.0 1.8 2.0 0.2 0.3 1.7 1.0 0.1 1.3 0.5 0.0 1.1 0.2 0.6 0.1 0.1 0.0 0.2 1.0 0.0 0.1 33.4 0.6 0.0 3.0 0.1 0.0 0.1 0.1 0.4 0.1 0.0 0.4 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.5 0.3 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 1.7 0.9 0.2 0.5 1.8 2.0 1.3 1.0 0.6 0.4 1.1 6.4 0.5 19.6 0.0 0.5 0.7 3.8 0.0 2.5 1.9 1.8 1.8 0.0 11.4 18.4 4.2 0.4 0.1 0.1 1.9 1.1 283.9 82.6 3.2 0.9 1.8 0.0 12.0 0.4 0.3 1.1 0.0 1.7 1.3 0.3 0.7 0.0 0.1 3.3 8.6 0.2 8.2 0.0 0.3 157.5 2.5 0.4 0.0 4.7 0.3 1.8 0.0 5.0 2.6 0.2 0.0 3.0 0.0 0.5 0.0 5.7 88.2 9.0 6.6 0.7 2.7 116.2 6.0 0.2 0.1 0.7 0.3 2.9 0.0 0.3 KATNAL2 "DKFZP667C165, MGC33211" ENSG00000167216 "Katanin catalytic subunit A1 like 2" Q8IYT4 18 46917492-47102243 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 84.2;Early spermatids: 91.8;Inhibitory neurons: 41.8;Late spermatids: 71.4;Oligodendrocytes: 38.7;Spermatocytes: 58.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 21.5;Daudi: 28.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040712, HPA042029" Approved Approved "Nucleoplasm,Intermediate filaments" No No "Cluster 21: B-cells - Adaptive immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Intermediate filaments" "HPA040712: AB_2677092, HPA042029: AB_2677807" "unprognostic (3.40e-1)" "unprognostic (7.75e-2)" "unprognostic (9.00e-3)" "unprognostic (9.28e-2)" "unprognostic (1.74e-2)" "unprognostic (6.55e-3)" "unprognostic (6.97e-2)" "unprognostic (1.28e-2)" "unprognostic (3.90e-2)" "unprognostic (5.36e-2)" "unprognostic (9.52e-6)" "unprognostic (1.28e-1)" "prognostic favorable (1.24e-7)" "unprognostic (1.64e-1)" "unprognostic (7.14e-4)" "unprognostic (1.06e-3)" "unprognostic (1.61e-1)" 5.3 3.4 9.6 1.8 11.1 2.7 4.0 14.4 14.7 3.4 23.1 2.6 1.4 2.3 5.5 2.6 7.1 4.4 4.4 9.1 9.2 10.4 6.9 3.3 3.2 10.6 11.5 3.3 2.9 18.0 8.0 1.7 11.2 4.3 2.5 10.8 4.4 2.7 6.1 7.4 2.2 1.8 8.6 3.7 2.2 15.5 10.3 1.9 17.5 2.9 2.1 2.3 3.1 12.9 2.7 5.7 3.5 21.5 7.1 7.9 1.6 2.4 2.1 1.9 2.5 0.2 7.5 28.2 2.2 4.2 2.6 0.9 6.9 0.7 1.6 2.6 3.7 1.3 2.0 0.4 2.8 1.7 2.4 16.5 2.6 3.5 0.9 4.9 0.7 12.8 1.0 2.3 11.5 2.7 1.9 3.7 7.6 4.0 3.9 7.8 1.5 0.1 6.4 0.4 7.6 8.8 2.7 0.5 1.0 11.9 15.5 16.7 1.5 7.1 0.7 2.7 1.7 1.8 1.5 19.7 3.7 18.0 13.4 0.1 0.1 0.1 0.2 0.2 0.2 0.5 0.2 0.1 0.0 0.6 0.3 0.3 0.2 0.1 0.2 0.1 0.0 0.0 9.6 11.1 14.4 14.7 9.1 9.2 10.6 11.5 11.2 8.6 10.3 12.9 3.7 0.0 1.1 84.2 1.0 1.5 3.0 2.9 8.0 9.9 1.6 1.3 2.9 1.5 5.2 3.7 6.2 0.0 0.2 2.5 13.7 0.9 91.8 22.6 6.2 2.5 0.0 1.7 28.2 0.2 0.0 3.1 3.6 1.6 0.0 3.9 2.2 4.2 3.6 11.8 41.8 0.7 2.0 1.9 0.9 71.4 1.5 1.5 3.6 18.7 0.9 2.6 0.0 26.7 38.7 0.2 0.3 2.2 0.4 1.0 0.2 12.1 35.2 2.3 0.0 7.5 1.9 58.7 4.6 2.8 1.1 0.1 0.6 2.6 2.3 1.9 KCTD9 "BTBD27, FLJ20038" ENSG00000104756 "Potassium channel tetramerization domain containing 9" Q7L273 8 25427847-25458476 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042468, HPA047902" Supported "Nucleoplasm,Intermediate filaments,Cytosol" No No "Cluster 4: T-regs - Cell cycle regulation" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm "Intermediate filaments, Cytosol" "HPA042468: , HPA047902: AB_2680205" "unprognostic (4.18e-2)" "unprognostic (3.90e-2)" "prognostic favorable (7.88e-4)" "unprognostic (7.04e-2)" "unprognostic (7.41e-2)" "unprognostic (1.05e-2)" "unprognostic (2.20e-2)" "unprognostic (6.01e-2)" "unprognostic (4.33e-1)" "unprognostic (2.43e-2)" "unprognostic (4.49e-3)" "unprognostic (2.30e-1)" "unprognostic (1.48e-1)" "unprognostic (6.62e-2)" "unprognostic (1.35e-1)" "unprognostic (1.31e-2)" "unprognostic (4.97e-3)" 18.4 8.2 4.9 11.5 5.8 21.5 22.3 7.9 6.5 15.4 8.6 21.1 19.6 11.3 13.0 23.8 14.6 13.3 38.3 5.5 5.9 12.8 10.8 13.4 12.2 9.1 7.7 14.2 11.2 11.0 9.8 12.0 10.0 17.4 22.6 12.9 17.5 15.6 29.5 19.0 17.7 14.5 7.8 9.4 12.8 12.9 6.9 14.7 13.7 36.7 14.4 15.6 18.7 6.9 46.4 32.4 34.5 11.9 44.0 58.0 28.2 68.6 61.4 44.1 44.5 23.4 33.2 30.1 28.6 69.0 62.3 30.3 30.6 32.3 52.9 15.4 18.2 35.3 30.2 21.7 53.2 12.3 25.1 44.8 38.5 40.2 33.2 26.9 37.8 29.6 37.8 23.0 50.7 12.4 48.2 21.6 16.8 35.8 17.0 18.6 39.8 11.2 45.0 26.1 8.8 11.4 52.7 23.1 35.8 30.8 17.8 14.2 42.2 48.5 28.2 94.1 37.6 6.6 12.9 39.1 33.9 21.8 35.8 0.7 0.5 1.2 1.0 0.7 1.0 0.6 1.0 1.0 0.3 0.3 0.6 0.9 0.5 0.2 0.9 1.0 1.1 0.4 4.9 5.8 7.9 6.5 5.5 5.9 9.1 7.7 10.0 7.8 6.9 6.9 19.5 32.1 18.5 18.6 8.9 74.4 36.4 26.0 31.9 13.7 20.4 12.7 61.1 5.7 24.2 27.6 25.0 9.4 23.3 53.8 13.7 17.6 6.5 12.8 12.7 16.8 10.2 20.2 14.3 27.2 17.6 32.5 8.2 17.9 20.3 10.9 12.5 9.0 9.3 3.3 12.9 16.0 18.3 9.3 18.5 5.2 30.7 12.9 30.2 36.5 8.5 8.1 18.6 17.1 13.6 36.6 21.6 55.7 17.1 52.6 25.8 10.4 17.4 19.6 6.6 21.6 26.2 35.6 26.4 41.6 54.7 11.2 19.8 14.4 17.7 46.0 KRT13 "CK13, K13, MGC161462, MGC3781" ENSG00000171401 "Keratin 13" P13646 17 41500981-41505705 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 40925.1;vagina: 13409.3" "Cell type enriched" "Detected in many" 4 "Squamous epithelial cells: 16844.0" "Group enriched" "Detected in many" 5 "cervical cancer: 899.2;head and neck cancer: 758.7;urothelial cancer: 504.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 93 "A-431: 2462.5;HaCaT: 1626.2" "CAB000133, HPA030877, HPA069771" Enhanced Enhanced "Intermediate filaments" NA NA 680000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "CAB000133: , HPA030877: AB_2673641, HPA069771: AB_2732141" "unprognostic (1.45e-1)" "unprognostic (6.23e-2)" "unprognostic (1.37e-1)" "unprognostic (2.19e-2)" "unprognostic (9.30e-5)" "unprognostic (7.30e-3)" "unprognostic (1.95e-1)" "unprognostic (1.77e-1)" "unprognostic (5.81e-3)" "prognostic unfavorable (1.02e-4)" "unprognostic (3.16e-1)" "prognostic unfavorable (1.45e-6)" "unprognostic (1.80e-1)" "unprognostic (2.76e-1)" "unprognostic (3.04e-2)" "unprognostic (4.33e-1)" 7.7 7.5 0.0 0.0 0.1 6.8 5.1 0.0 0.0 6884.6 0.0 5.6 0.1 10.2 0.0 40925.1 7.0 8.8 9.2 0.0 0.1 5.6 12.8 6.0 0.3 0.0 0.0 9.9 17.2 0.0 26.9 0.0 0.0 115.2 0.0 0.0 6881.1 3.8 9.8 20.5 8.5 14.2 0.0 7.7 31.3 6.9 0.0 13.6 6.1 0.0 1855.2 924.7 13409.3 0.0 2462.5 0.6 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.6 0.8 7.1 0.6 0.0 0.0 1626.2 0.0 0.4 0.0 1.4 0.0 4.5 21.8 0.0 0.0 1.7 1.3 0.0 0.8 0.0 0.0 0.3 0.0 0.0 5.4 1.2 0.0 1.3 0.1 0.1 0.1 14.8 0.3 0.2 1.2 0.3 0.0 10.7 0.0 0.0 1.9 2.0 7.7 0.0 2.3 6.4 5.1 0.0 0.4 0.0 6.6 0.3 6.3 5.8 1.9 4.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 16.0 1.1 0.0 0.9 2.8 545.6 17.1 146.8 0.0 2.3 4.6 0.6 1.5 94.5 0.0 0.0 0.1 0.2 0.6 0.0 0.0 1.2 2.7 0.2 11.4 1.2 5.5 0.0 0.0 0.5 12.6 0.0 4.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 8.2 0.0 0.0 3.2 55.9 13.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.7 286.6 27.1 227.9 0.1 0.1 3.3 0.0 0.0 0.0 16.9 0.2 0.6 16844.0 1.6 0.4 8.8 0.0 0.4 3645.4 KRT14 "EBS3, EBS4" ENSG00000186847 "Keratin 14" P02533 17 41582279-41586895 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Ectodermal dysplasia, Epidermolysis bullosa, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 6940.5" "Group enriched" "Detected in many" 9 "Basal keratinocytes: 35588.3;Suprabasal keratinocytes: 11677.1" "Cancer enriched" "Detected in many" 5 "head and neck cancer: 5910.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 4065.2;HBEC3-KT: 2003.9;hTCEpi: 2448.6;hTERT-HME1: 794.2;U-2197: 696.0" "Not detected" "Not detected" "Region enriched" "Detected in many" 7 "spinal cord: 36.3" "CAB000134, HPA000452, HPA000539, HPA023040" Enhanced Enhanced "Intermediate filaments" NA NA 1600000000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Intermediate filaments" "CAB000134: , HPA000452: AB_1079177, HPA000539: , HPA023040: AB_1852201" "prognostic favorable (2.66e-4)" "unprognostic (1.64e-1)" "unprognostic (1.01e-2)" "unprognostic (1.42e-2)" "unprognostic (1.66e-1)" "unprognostic (1.02e-2)" "unprognostic (2.03e-2)" "unprognostic (2.74e-1)" "unprognostic (1.35e-1)" "unprognostic (1.00e-2)" "unprognostic (5.74e-3)" "unprognostic (1.49e-8)" "unprognostic (8.91e-2)" "unprognostic (2.00e-1)" "unprognostic (8.80e-3)" "unprognostic (1.22e-2)" 15.8 1.2 0.0 0.0 0.0 2.7 332.7 0.0 0.0 412.0 0.0 1.7 0.0 0.9 0.0 1304.2 1.7 0.0 3.5 0.0 0.0 0.8 2.5 1.7 0.0 0.0 0.0 1.3 2.9 0.0 4.3 2.2 0.1 29.1 0.0 0.0 702.1 3.8 15.9 6940.5 2.1 0.1 0.0 0.9 1.7 1.5 0.0 186.7 2.3 0.0 262.3 0.7 846.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.8 0.1 0.0 0.3 0.0 0.0 0.0 0.6 0.1 0.7 0.0 4065.2 0.0 2003.9 0.2 0.0 0.0 0.1 1.6 0.0 0.1 0.2 2.5 0.1 2448.6 3.0 794.2 0.0 0.1 0.0 0.5 3.6 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.6 0.2 0.6 0.0 0.1 0.1 0.0 0.2 0.5 0.0 0.0 0.4 0.0 0.3 9.1 1.7 696.0 0.0 0.9 0.0 0.0 3.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.5 35588.3 1072.7 181.5 2407.4 0.0 103.5 740.9 0.3 0.0 6.0 0.0 0.0 17.9 3.2 7.3 0.0 0.1 0.0 0.1 0.0 129.0 0.0 0.0 0.0 0.0 127.0 116.5 0.0 0.2 0.0 0.0 0.0 0.0 3.3 0.0 0.0 3.4 0.0 0.0 1833.4 0.0 0.0 9.3 1990.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 3.5 0.0 9.9 702.0 96.8 0.0 2.3 0.0 0.0 0.0 96.3 0.0 0.1 83.2 11677.1 2.5 62.1 0.1 2.3 100.0 KRT15 "CK15, K15, K1CO" ENSG00000171346 "Keratin 15" P19012 17 41513745-41522529 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "breast: 419.1;esophagus: 1156.7;skin 1: 1319.5;vagina: 423.3" "Group enriched" "Detected in many" 4 "Basal prostatic cells: 2789.9;Basal squamous epithelial cells: 8290.4;Squamous epithelial cells: 4637.9" "Cancer enhanced" "Detected in many" "cervical cancer: 178.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 10 "HaCaT: 1156.8;hTCEpi: 1001.5" "Region enhanced" "Detected in single" "white matter: 1.9" "Not detected" "Not detected" "HPA023910, HPA024554" Enhanced Supported "Nucleoplasm,Intermediate filaments" No No 480000000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" Nucleoplasm "HPA023910: AB_1852205, HPA024554: AB_1852207" "prognostic favorable (4.50e-4)" "unprognostic (9.14e-2)" "unprognostic (3.28e-2)" "unprognostic (1.19e-3)" "unprognostic (3.57e-2)" "unprognostic (8.84e-2)" "unprognostic (6.12e-3)" "unprognostic (1.70e-1)" "unprognostic (2.13e-1)" "unprognostic (8.65e-3)" "unprognostic (9.91e-3)" "unprognostic (2.09e-1)" "unprognostic (2.24e-11)" "unprognostic (6.91e-3)" "unprognostic (2.62e-1)" "unprognostic (1.33e-5)" "unprognostic (5.35e-2)" 4.7 0.3 0.1 0.2 0.0 0.7 419.1 0.0 0.1 148.2 0.2 1.1 1.5 0.3 2.2 1156.7 32.4 2.8 0.7 0.1 0.0 0.3 0.6 4.3 0.0 0.1 0.1 0.4 1.4 0.0 1.2 0.3 0.1 182.8 1.6 0.0 140.0 4.1 0.7 1319.5 2.3 0.1 0.0 0.3 1.6 8.0 0.1 93.7 0.5 0.0 77.6 9.5 423.3 0.1 56.4 7.4 0.0 0.0 0.0 0.0 0.7 5.3 1.3 0.3 0.2 5.9 20.2 0.0 1.8 0.6 14.0 1156.8 0.0 41.8 0.2 0.6 0.0 0.0 7.7 1.9 0.0 0.1 4.7 0.0 1001.5 2.2 6.9 2.7 3.4 0.0 0.3 0.5 0.2 3.5 0.1 0.5 0.0 3.9 6.2 0.0 0.0 104.9 3.3 5.9 2.6 0.1 1.1 15.0 1.2 0.3 20.3 0.0 18.6 0.3 2.8 0.3 2.2 0.1 0.1 0.0 8.3 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 6.1 12.8 10.3 0.0 2.7 1309.8 2789.9 1190.9 8290.4 0.6 577.7 670.3 0.8 5.7 287.5 1.8 0.0 0.7 16.9 18.3 1.9 8.5 117.6 4.1 0.7 22.9 4.8 0.0 0.1 7.5 7.7 21.7 4.6 8.2 2.5 0.0 0.0 0.0 0.4 0.0 0.1 10.3 189.2 0.0 61.7 44.4 1.5 17.2 320.2 0.0 0.0 0.2 0.0 0.0 0.1 14.1 10.5 0.4 88.7 872.9 8.6 0.1 57.7 0.6 0.0 0.4 32.1 0.6 0.8 4637.9 193.6 1.2 21.6 0.1 7.2 906.0 KRT16 NEPPK ENSG00000186832 "Keratin 16" P08779 17 41609778-41615899 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 307.2;esophagus: 1025.8;skin 1: 360.7;vagina: 489.4" "Group enriched" "Detected in many" 6 "Basal keratinocytes: 906.1;Basal prostatic cells: 596.6;Suprabasal keratinocytes: 1348.4;Urothelial cells: 506.9" "Group enriched" "Detected in many" 7 "cervical cancer: 713.1;head and neck cancer: 2720.5;melanoma: 712.9" "Group enriched" "Detected in some" 4 "cerebellum: 3.9;hippocampal formation: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "hTCEpi: 816.8" "Not detected" "Not detected" "CAB000136, HPA000539" Approved Approved "Intermediate filaments" NA NA 1700000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "Intermediate filaments" "CAB000136: , HPA000539: " "unprognostic (3.95e-3)" "unprognostic (6.90e-2)" "unprognostic (1.38e-1)" "unprognostic (1.23e-1)" "unprognostic (1.41e-2)" "unprognostic (1.00e-2)" "unprognostic (7.14e-3)" "unprognostic (1.03e-3)" "unprognostic (2.05e-1)" "unprognostic (3.07e-2)" "prognostic unfavorable (1.09e-5)" "unprognostic (8.23e-2)" "unprognostic (6.53e-8)" "unprognostic (3.81e-1)" "unprognostic (1.83e-1)" "unprognostic (7.40e-2)" "unprognostic (3.61e-2)" 7.1 1.4 0.2 0.1 0.3 0.3 17.4 3.9 0.6 307.2 0.0 0.2 0.0 1.0 0.0 1025.8 0.7 2.4 0.5 1.0 0.0 0.8 0.4 0.2 0.1 0.0 0.0 0.3 0.7 0.0 1.4 0.1 0.1 6.3 0.0 0.0 180.6 37.7 0.5 360.7 0.2 0.1 0.0 0.2 0.6 2.6 0.0 16.9 0.3 0.0 112.1 5.5 489.4 0.4 20.0 1.7 0.0 0.0 0.2 0.0 0.2 1.5 0.4 0.5 0.2 0.3 4.9 0.1 2.9 0.1 0.2 24.8 0.0 5.6 0.3 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 816.8 0.3 17.6 0.0 0.0 0.0 0.3 0.0 0.2 0.5 0.0 0.3 0.0 127.1 0.7 0.0 0.2 98.1 0.8 6.2 0.0 0.0 57.1 1.5 0.0 0.9 0.0 0.0 0.2 0.0 1.6 4.5 0.4 0.1 0.0 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 3.9 0.6 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.3 906.1 596.6 70.1 16.5 0.0 37.8 27.1 0.1 0.0 94.6 1.8 0.0 0.1 0.6 0.0 0.0 1.0 0.0 2.6 0.6 9.2 0.0 0.0 0.0 5.8 3.2 11.5 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 94.1 0.0 0.3 1.1 64.0 0.0 0.0 0.0 0.0 0.0 0.0 82.7 0.0 0.0 0.0 127.3 0.0 0.0 17.1 0.0 0.0 0.0 9.3 0.0 0.3 88.1 1348.4 0.1 3.4 0.0 0.0 506.9 KRT17 PCHC1 ENSG00000128422 "Keratin 17" Q04695 17 41619442-41624842 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 382.1;skin 1: 949.4;urinary bladder: 632.2" "Group enriched" "Detected in many" 5 "Basal prostatic cells: 13196.1;Prostatic glandular cells: 5931.6;Urothelial cells: 8499.3" "Cancer enhanced" "Detected in all" "head and neck cancer: 3317.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "hTCEpi: 20287.9;SiHa: 8539.7" "Not detected" "Not detected" "CAB000029, HPA000452, HPA000453, HPA000539, HPA045062" Enhanced Enhanced "Intermediate filaments" Yes No 610000000 "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Intermediate filaments" "CAB000029: AB_2133155, HPA000452: AB_1079177, HPA000453: AB_1079176, HPA000539: , HPA045062: AB_2679204" "prognostic favorable (4.44e-4)" "unprognostic (1.43e-1)" "unprognostic (1.15e-1)" "unprognostic (3.65e-3)" "unprognostic (4.46e-2)" "unprognostic (4.34e-1)" "unprognostic (4.36e-3)" "unprognostic (1.32e-2)" "unprognostic (2.27e-1)" "unprognostic (1.29e-1)" "unprognostic (7.86e-3)" "unprognostic (1.53e-1)" "prognostic unfavorable (5.74e-4)" "unprognostic (1.82e-1)" "unprognostic (1.77e-1)" "unprognostic (2.20e-1)" "unprognostic (3.89e-1)" 5.1 0.4 4.9 0.8 5.3 2.8 382.1 3.5 5.8 102.2 3.5 2.0 0.8 4.3 14.1 320.4 6.9 1.9 2.7 6.3 3.3 3.1 0.6 9.8 0.3 3.5 3.4 0.9 2.6 0.5 6.6 7.0 3.5 132.4 0.3 0.3 263.2 116.1 0.9 949.4 0.6 1.0 3.4 0.4 2.3 4.5 3.3 142.7 1.6 0.0 97.8 632.2 212.3 4.7 212.5 0.2 0.0 0.0 0.8 0.9 48.8 1.9 0.4 2.8 2.7 16.8 1.9 1.0 14.7 0.2 0.4 2101.7 0.1 2129.1 1.9 0.3 1.6 2.0 910.8 2.0 0.5 1.9 2.2 0.4 20287.9 1.3 1539.9 0.0 1.0 0.0 1.0 1.5 0.4 0.7 0.7 0.3 0.4 237.2 0.0 0.7 3.1 1.7 0.8 770.5 0.3 0.2 8539.7 3.8 0.9 4.8 0.3 1.4 0.8 0.0 401.5 0.2 1.0 0.9 0.4 3.1 1.4 77.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 5.3 3.5 5.8 6.3 3.3 3.5 3.4 3.5 3.4 3.3 4.7 5.6 22.4 7.2 0.3 0.5 139.6 13196.1 338.0 327.8 0.2 158.4 792.8 0.1 0.0 415.8 36.8 0.0 21.5 3.8 0.9 0.0 567.7 0.4 116.9 13.5 54.5 1.8 0.0 3.2 202.1 148.5 87.9 0.0 134.1 3.8 0.0 0.0 0.0 3.8 20.2 0.5 0.6 36.7 0.0 14.1 1.6 2.1 37.5 10.6 3.7 6.7 0.0 0.0 0.5 1.4 1754.5 2.5 212.5 0.0 5931.6 0.1 0.4 100.1 0.0 0.0 0.9 101.0 0.3 0.4 48.2 124.3 5.7 60.8 3.1 0.8 8499.3 KRT19 "CK19, K19, K1CS, MGC15366" ENSG00000171345 "Keratin 19" P08727 17 41523617-41528308 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 889.0;salivary gland: 810.7;urinary bladder: 781.4" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 7444.0;Club cells: 5055.9;Ductal cells: 4717.9;Extravillous trophoblasts: 6919.3;Pancreatic endocrine cells: 7374.9;Proximal enterocytes: 8623.3;Urothelial cells: 5959.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 1945.3;HBEC3-KT: 2945.0;MCF7: 2220.9;RT4: 3146.7;SK-BR-3: 5446.1;T-47d: 3674.2" "Not detected" "Not detected" "CAB000031, HPA002465" Enhanced Supported "Intermediate filaments" NA NA 300000000 "Cluster 40: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Intermediate filaments" "CAB000031: AB_2234418, HPA002465: AB_1079179" "unprognostic (1.09e-1)" "unprognostic (1.83e-1)" "unprognostic (3.86e-2)" "unprognostic (1.59e-2)" "unprognostic (2.24e-2)" "unprognostic (1.13e-1)" "unprognostic (2.29e-1)" "unprognostic (2.80e-2)" "unprognostic (3.14e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (6.82e-5)" "unprognostic (1.90e-2)" "prognostic unfavorable (2.98e-5)" "unprognostic (3.52e-2)" "unprognostic (2.14e-1)" "unprognostic (3.08e-2)" "unprognostic (2.35e-2)" 89.3 18.7 2.0 61.7 2.4 0.3 403.3 7.9 2.5 250.0 1.6 525.7 348.3 57.9 72.0 889.0 176.1 298.6 13.5 1.5 1.7 141.8 7.7 204.1 0.4 1.6 2.9 74.4 48.8 14.3 15.6 175.1 2.2 208.3 359.2 0.1 810.7 194.2 1.3 141.9 776.1 46.5 1.4 1.2 631.5 3.4 1.8 127.8 28.3 1.6 98.3 781.4 317.0 1.8 2.6 343.4 0.0 6.3 0.7 1.8 1169.3 412.1 0.5 12.8 2.9 992.6 1945.3 0.4 393.3 199.0 1.5 1044.6 0.1 2945.0 2.5 0.8 10.4 0.2 213.4 692.3 30.3 0.0 82.0 0.7 524.9 9.0 0.4 0.2 26.2 0.0 148.4 2.5 0.1 2220.9 5.9 3.0 18.5 1323.5 492.7 2.9 0.1 5.8 1335.4 3146.7 40.0 1.7 3.3 5446.1 0.1 266.5 3674.2 0.3 1.7 3.6 6.1 7.7 0.7 1.1 0.8 2.0 1.5 0.3 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.0 2.4 7.9 2.5 1.5 1.7 1.6 2.9 2.2 1.4 1.8 1.8 10.5 673.1 185.5 0.0 17.8 5.2 4317.3 7444.0 1715.8 0.0 1393.0 867.5 2.9 662.0 5055.9 892.0 0.0 1160.8 20.5 3599.6 1.9 4717.9 0.1 737.2 102.8 41.9 362.5 0.0 0.1 2589.9 6919.3 171.8 1571.4 1010.7 94.6 1.0 1.1 0.7 179.0 0.0 0.1 1382.4 2720.0 2.6 2.5 2.6 37.9 25.5 190.3 1.0 30.0 0.8 0.0 0.0 0.0 7374.9 3399.6 88.8 19.9 2228.8 8623.3 26.7 1954.3 0.0 0.0 0.0 240.0 1.1 1.6 1302.6 1.1 2127.5 36.1 4.8 1619.0 5959.8 KRT24 "FLJ20261, MGC138169, MGC138173" ENSG00000167916 "Keratin 24" Q2M2I5 17 40697991-40703752 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "esophagus: 178.0;lymphoid tissue: 76.3" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 6.0;Fibroblasts: 4.6;Leydig cells: 3.1;Syncytiotrophoblasts: 4.0" "Group enriched" "Detected in some" 4 "cervical cancer: 9.6;head and neck cancer: 15.0;urothelial cancer: 6.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 14 "SK-BR-3: 7.0" "Region enriched" "Detected in single" 10 "cerebellum: 1.0" "Low region specificity" "Detected in some" HPA022978 Uncertain Approved "Intermediate filaments,Cytosol" No NA 300000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Intermediate filaments, Cytosol" "HPA022978: AB_1852230" "unprognostic (2.74e-2)" "unprognostic (1.05e-2)" "unprognostic (1.45e-1)" "unprognostic (3.16e-2)" "unprognostic (2.47e-1)" "unprognostic (3.75e-1)" "unprognostic (2.74e-1)" "unprognostic (2.95e-1)" "unprognostic (3.37e-2)" 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 5.3 0.0 8.0 0.0 0.1 16.7 178.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.5 0.0 0.0 5.8 0.2 2.2 1.6 0.0 0.0 0.3 0.5 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 76.3 2.6 13.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 1.2 4.6 0.0 0.7 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 4.0 0.0 0.0 0.0 0.0 KRT4 "CK4, CYK4, K4" ENSG00000170477 "Keratin 4" P19013 12 52806549-52814116 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "esophagus: 19735.6" "Cell type enriched" "Detected in some" 18 "Squamous epithelial cells: 5828.7" "Group enriched" "Detected in many" 5 "cervical cancer: 94.3;head and neck cancer: 151.8;stomach cancer: 73.1;urothelial cancer: 38.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 33 "HaCaT: 734.9;SK-BR-3: 361.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002154, HPA034881" Enhanced Supported "Intermediate filaments" NA NA 600000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "CAB002154: AB_563803, HPA034881: AB_2674370" "unprognostic (4.04e-1)" "unprognostic (3.22e-3)" "unprognostic (5.16e-3)" "unprognostic (8.52e-3)" "unprognostic (1.20e-1)" "unprognostic (2.64e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (3.26e-4)" "unprognostic (2.85e-3)" "unprognostic (2.84e-2)" "unprognostic (2.58e-11)" "unprognostic (1.64e-1)" "unprognostic (6.97e-2)" "unprognostic (1.16e-1)" "prognostic unfavorable (6.26e-4)" 1.5 1.5 0.0 0.0 0.0 0.0 0.9 0.0 0.0 513.5 0.0 1.1 0.0 1.2 0.0 19735.6 9.5 3.1 7.2 0.0 0.0 0.9 2.6 17.3 0.0 0.0 0.0 1.8 2.8 0.0 8.9 0.0 0.0 4.3 0.0 0.0 2124.1 0.0 2.6 3.9 1.7 0.9 0.0 1.5 8.6 0.8 0.0 2.0 1.0 0.1 1418.0 4.4 1040.2 0.0 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 1.8 0.0 0.1 0.0 734.9 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.5 1.3 0.0 0.9 0.0 0.0 0.0 0.0 0.0 1.9 0.3 0.0 1.4 0.0 0.2 0.0 15.5 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.0 1.0 361.6 0.0 0.0 2.0 0.0 2.0 0.0 0.2 0.0 0.0 0.0 1.0 0.9 0.5 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.4 3.3 0.0 0.0 0.0 6.5 36.9 23.3 0.0 0.5 2.9 0.5 0.0 308.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.6 0.2 2.9 0.0 0.0 0.0 0.0 0.0 2.6 0.0 1.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 28.5 0.0 0.0 0.1 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.9 6.9 0.0 0.1 53.7 0.0 0.0 0.0 5.3 0.0 0.1 5828.7 0.0 0.0 2.0 0.0 0.0 54.4 KRT5 "EBS2, KRT5A" ENSG00000186081 "Keratin 5" P13647 12 52514575-52520530 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 5865.0;skin 1: 5885.4;vagina: 2150.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 5870.1;Basal prostatic cells: 1037.6;Basal squamous epithelial cells: 1571.3;Squamous epithelial cells: 4370.9;Suprabasal keratinocytes: 2020.2" "Group enriched" "Detected in many" 4 "cervical cancer: 1863.2;head and neck cancer: 3340.4" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 326 "plasmacytoid DC: 32.6" "Lineage enriched" "Detected in single" 326 "dendritic cells: 32.6" "Group enriched" "Detected in some" 7 "HaCaT: 3368.0;HBEC3-KT: 5990.5;hTCEpi: 13326.8" "Region enriched" "Detected in many" 8 "spinal cord: 36.4" "CAB000027, CAB000129, HPA059479" Enhanced Approved "Intermediate filaments" NA NA 3600000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "CAB000027: AB_2281083, CAB000129: , HPA059479: AB_2684034" "prognostic favorable (1.27e-4)" "unprognostic (9.81e-2)" "unprognostic (1.14e-1)" "unprognostic (1.29e-2)" "unprognostic (1.84e-1)" "unprognostic (1.14e-1)" "unprognostic (1.33e-1)" "unprognostic (7.20e-2)" "unprognostic (2.82e-1)" "unprognostic (1.90e-1)" "unprognostic (1.41e-2)" "unprognostic (1.73e-1)" "unprognostic (6.01e-7)" "unprognostic (3.46e-2)" "unprognostic (5.56e-2)" "unprognostic (7.96e-2)" "unprognostic (2.81e-3)" 10.0 1.7 0.2 1.8 0.8 4.6 252.5 0.7 0.5 826.2 58.9 1.9 0.0 2.0 97.2 5865.0 12.5 2.0 3.8 1.7 0.0 1.3 3.5 6.4 3.0 0.1 0.0 2.2 4.7 0.1 8.2 2.0 0.1 125.8 0.0 0.0 880.3 100.0 9.9 5885.4 1.8 0.6 0.1 1.7 5.0 2.1 0.6 527.1 3.0 0.3 648.6 93.2 2150.9 0.4 50.6 0.0 0.0 0.0 2.3 0.2 0.8 0.0 0.0 0.0 0.0 1.0 0.3 2.4 0.5 0.2 0.0 3368.0 0.2 5990.5 0.2 0.0 0.0 0.2 0.1 0.0 0.6 1.4 2.8 0.3 13326.8 0.6 1049.7 0.0 0.8 0.0 1.8 4.0 0.3 0.0 0.2 0.4 0.2 0.0 0.0 0.2 1.0 1.2 0.8 0.9 0.0 0.1 1.2 0.8 0.0 0.0 0.0 0.0 1.5 0.0 0.9 0.5 0.2 10.1 1.0 0.9 4.0 1.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.6 0.0 0.1 0.2 0.8 0.7 0.5 1.7 0.0 0.1 0.0 0.1 0.1 0.6 0.4 1.7 0.0 1.1 0.0 0.4 5870.1 1037.6 627.1 1571.3 0.0 43.6 226.2 0.5 0.0 180.7 0.0 0.0 0.0 39.8 0.0 0.0 0.5 0.8 31.3 1.2 26.4 0.0 0.0 0.5 0.0 0.0 29.0 0.0 21.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.7 0.0 273.6 0.1 0.6 7.3 286.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 22.2 789.7 0.0 0.1 34.8 0.0 0.0 0.2 33.4 0.0 0.0 4370.9 2020.2 0.0 17.8 0.0 0.1 459.8 KRT6A "CK6C, CK6D, K6C, K6D, KRT6C, KRT6D" ENSG00000205420 "Keratin 6A" P02538 12 52487176-52493257 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Allergen, Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "cervix: 2523.3;esophagus: 7338.5;vagina: 4945.4" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 674.0;Club cells: 200.5;Squamous epithelial cells: 876.0;Suprabasal keratinocytes: 151.4;Urothelial cells: 306.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 3892.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "hTCEpi: 9761.7" "HPA045697, HPA061168" Supported Enhanced "Intermediate filaments" NA NA 4500000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "HPA045697: AB_2679422, HPA061168: AB_2684440" "unprognostic (8.10e-3)" "unprognostic (2.11e-1)" "unprognostic (2.78e-2)" "unprognostic (1.06e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.45e-4)" "unprognostic (2.43e-1)" "unprognostic (3.73e-2)" "unprognostic (1.31e-3)" "unprognostic (1.29e-1)" "unprognostic (2.89e-9)" "unprognostic (8.80e-2)" "unprognostic (7.20e-2)" "unprognostic (1.72e-1)" "unprognostic (2.13e-2)" 3.1 1.5 0.0 1.9 0.0 0.1 6.9 0.0 0.0 2523.3 0.0 1.2 0.0 1.3 0.0 7338.5 9.1 0.9 1.8 0.0 0.0 1.1 2.6 3.4 0.0 0.0 0.0 2.3 3.3 0.0 3.1 8.8 0.0 5.0 0.0 0.0 1025.5 0.0 1.9 480.0 1.3 0.4 0.0 1.4 4.9 1.0 0.0 33.6 1.5 0.0 628.6 19.7 4945.4 0.0 1.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 3.9 0.0 0.0 1143.8 0.0 2414.3 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.5 0.6 0.3 9761.7 0.2 306.7 0.0 0.3 0.0 0.7 0.8 0.0 0.0 0.0 0.0 0.0 14.0 0.3 0.1 0.5 0.0 0.3 0.0 0.0 0.0 20.4 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.5 0.0 0.0 0.2 0.2 0.4 0.9 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 105.5 79.0 674.0 12.0 0.0 0.6 1.7 0.0 0.0 200.5 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 2.6 0.2 0.8 0.0 0.0 0.0 0.0 0.0 1.8 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.7 0.0 5.5 0.0 0.0 0.7 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 100.4 0.0 0.0 24.5 0.0 0.0 0.0 11.8 0.0 0.0 876.0 151.4 0.0 1.7 0.0 0.1 306.8 KRT6B KRTL1 ENSG00000185479 "Keratin 6B" P04259 12 52446651-52452146 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 228.2;esophagus: 934.5;skin 1: 285.1;vagina: 229.6" "Cell type enriched" "Detected in some" 4 "Squamous epithelial cells: 217.5" "Group enriched" "Detected in many" 5 "head and neck cancer: 1424.3;melanoma: 472.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "OE19: 148.7" "CAB000130, HPA045697, HPA061168" Supported Approved "Intermediate filaments" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "CAB000130: , HPA045697: AB_2679422, HPA061168: AB_2684440" "prognostic favorable (9.44e-4)" "unprognostic (3.27e-2)" "unprognostic (1.93e-1)" "unprognostic (1.28e-1)" "unprognostic (1.21e-1)" "unprognostic (1.75e-2)" "unprognostic (2.07e-3)" "unprognostic (2.27e-1)" "unprognostic (1.98e-1)" "unprognostic (1.03e-1)" "unprognostic (5.77e-2)" "unprognostic (9.63e-2)" "unprognostic (3.29e-1)" "prognostic unfavorable (9.52e-4)" 0.9 0.2 0.0 2.0 0.0 0.1 16.2 0.0 0.0 228.2 0.0 0.5 0.0 0.1 0.0 934.5 0.2 0.2 0.3 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.2 0.7 0.0 0.3 0.0 0.0 0.2 0.0 0.0 168.6 0.0 0.3 285.1 0.2 0.0 0.0 0.1 0.7 0.2 0.0 2.1 0.1 0.0 74.3 0.2 229.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.9 0.0 27.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 29.9 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 148.7 1.1 0.0 0.1 13.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 20.6 1.8 40.4 0.0 0.0 28.7 16.8 0.1 0.0 16.3 0.0 0.0 0.0 0.9 0.3 0.0 46.2 1.8 0.0 0.0 0.9 0.0 0.0 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 2.0 0.0 1.7 1.3 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 5.6 0.0 0.0 2.8 0.0 0.0 0.0 1.4 0.0 0.2 217.5 32.7 0.0 0.3 0.0 0.6 5.9 KRT6C KRT6E ENSG00000170465 "Keratin 6C" P48668 12 52468516-52473805 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 211.7;esophagus: 799.4;vagina: 333.5" "Cell type enriched" "Detected in some" 60 "Squamous epithelial cells: 234.3" "Group enriched" "Detected in many" 5 "head and neck cancer: 564.7;melanoma: 242.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "RPMI-8226: 94.1" "HPA045697, HPA061168" Supported Approved "Intermediate filaments" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "HPA045697: AB_2679422, HPA061168: AB_2684440" "unprognostic (3.18e-2)" "unprognostic (6.26e-3)" "unprognostic (6.63e-2)" "unprognostic (1.54e-3)" "unprognostic (6.97e-2)" "prognostic unfavorable (1.23e-5)" "unprognostic (1.83e-1)" "unprognostic (1.87e-2)" "unprognostic (3.25e-2)" "unprognostic (2.24e-1)" "unprognostic (2.84e-1)" "unprognostic (4.50e-2)" 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 211.7 0.0 0.1 0.0 0.1 0.0 799.4 0.2 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 144.3 0.0 0.1 24.7 0.1 0.0 0.0 0.1 0.4 0.0 0.0 1.0 0.1 0.0 9.5 0.1 333.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 94.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 1.2 1.3 2.2 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 234.3 2.4 0.0 0.0 0.0 0.2 3.9 KRT7 "CK7, K2C7, K7, SCL" ENSG00000135480 "Keratin 7" P08729 12 52232520-52252186 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 905.8;thyroid gland: 593.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1756.7;Ductal cells: 2931.3;Exocrine glandular cells: 2143.5;Extravillous trophoblasts: 4196.1;Pancreatic endocrine cells: 6163.7;Prostatic glandular cells: 2386.6;Urothelial cells: 1900.8" "Cancer enhanced" "Detected in many" "urothelial cancer: 560.1" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 4 "intermediate monocyte: 1.1" "Lineage enriched" "Detected in single" 4 "monocytes: 1.1" "Cell line enhanced" "Detected in many" "A549: 2418.2;BEWO: 2737.9;HBEC3-KT: 6225.3;hTERT-HME1: 2433.8;RT4: 7463.2;SiHa: 5833.6;SK-BR-3: 3363.4" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000028, HPA007272, HPA007315, CAB079970" Enhanced Approved "Intermediate filaments,Cytosol" NA NA 1300000000 "Cluster 7: Monocytes - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 15: RT4 - Unknown function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Intermediate filaments" Cytosol "CAB000028: AB_2134589, CAB079970: , HPA007272: AB_1079181, HPA007315: " "unprognostic (2.71e-3)" "unprognostic (3.09e-1)" "unprognostic (2.20e-1)" "prognostic unfavorable (1.99e-4)" "unprognostic (2.22e-2)" "unprognostic (8.59e-2)" "unprognostic (1.27e-1)" "unprognostic (5.44e-3)" "unprognostic (2.74e-1)" "prognostic unfavorable (9.42e-5)" "prognostic unfavorable (7.78e-5)" "unprognostic (4.54e-2)" "prognostic favorable (2.77e-9)" "unprognostic (2.82e-1)" "unprognostic (1.43e-2)" "unprognostic (3.28e-1)" "unprognostic (3.98e-3)" 27.1 0.7 0.0 1.4 0.0 0.3 272.9 0.0 0.2 48.4 0.0 1.6 0.4 12.9 15.2 91.7 75.9 82.4 5.6 0.0 0.0 147.5 14.2 325.2 1.7 0.2 0.0 2.4 57.4 5.6 12.0 265.1 0.2 58.1 0.7 0.3 905.8 213.2 1.7 78.3 1.3 0.4 0.1 0.8 17.8 0.8 0.1 3.3 593.0 2.0 6.7 389.8 20.1 0.4 4.9 2418.2 0.6 1.7 2.8 0.0 2737.9 509.6 0.6 261.3 23.6 7.6 1683.1 0.3 1.4 176.3 0.8 1871.6 0.2 6225.3 13.3 3.0 0.0 2.2 1179.8 8.0 57.4 1.5 1.5 1.3 380.7 1.3 2433.8 1.0 267.4 0.0 0.7 2.2 0.1 13.7 1.8 3.7 7.6 1.1 2.6 2.0 4.8 38.6 1520.5 7463.2 3.5 2.4 5833.6 3363.4 0.0 27.5 130.3 0.0 2028.2 1.9 3.7 2.4 1.1 1.8 0.4 2.0 2.0 1.6 1.2 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.2 0.1 0.1 0.4 8.1 653.9 109.4 0.0 2.5 3.6 1172.6 173.6 8.0 0.0 451.3 426.3 0.8 724.9 684.8 360.5 0.0 1756.7 8.9 2.2 135.0 2931.3 16.1 106.2 20.4 30.6 6.6 0.0 0.1 2143.5 4196.1 29.9 14.3 253.2 3.8 0.1 4.2 2.9 189.9 0.0 0.0 3.5 954.2 3.4 4.6 140.0 3.7 11.0 131.6 0.0 35.6 0.0 0.0 0.0 0.0 6163.7 0.3 0.4 1.4 2386.6 0.2 8.5 249.2 0.0 0.0 7.6 72.1 0.6 1.3 35.3 2.3 1442.5 9.2 0.0 4.4 1900.8 KRT74 "K6IRS4, KRT5C, KRT6IRS4" ENSG00000170484 "Keratin 74" Q7RTS7 12 52565782-52573843 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Ectodermal dysplasia, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "epididymis: 5.6;skin 1: 16.3" "Cell type enriched" "Detected in some" 5 "Late spermatids: 5.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA040655, HPA048596" Enhanced Approved "Nucleoli,Intermediate filaments,Cytosol" NA NA 130000000 "Cluster 61: Skin - Cornification" "Cluster 31: Spermatids - Spermatogenesis" "Intermediate filaments" "Nucleoli, Cytosol" "HPA040655: , HPA048596: AB_2680457" "unprognostic (6.75e-3)" "unprognostic (3.93e-1)" "unprognostic (1.60e-1)" "unprognostic (2.49e-2)" "unprognostic (9.46e-2)" "unprognostic (2.29e-1)" "unprognostic (8.54e-2)" "unprognostic (1.02e-1)" 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 KRT80 KB20 ENSG00000167767 "Keratin 80" Q6KB66 12 52168996-52192014 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skin 1: 219.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 25.9;Ductal cells: 63.0;Endometrial ciliated cells: 33.0;Glandular and luminal cells: 33.5;Pancreatic endocrine cells: 48.4;Suprabasal keratinocytes: 37.4;Syncytiotrophoblasts: 58.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 202.5;MCF7: 287.3;SK-BR-3: 127.7;U-2 OS: 174.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA077836, HPA077918" Enhanced "Intermediate filaments" No No 230000000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 1: Pancreatic cells - Digestion" "Intermediate filaments" "HPA077836: AB_2686857, HPA077918: AB_2686871" "prognostic unfavorable (1.05e-4)" "unprognostic (5.45e-3)" "unprognostic (5.35e-2)" "unprognostic (9.19e-3)" "unprognostic (2.85e-4)" "unprognostic (6.68e-2)" "unprognostic (2.06e-3)" "unprognostic (1.26e-3)" "unprognostic (5.60e-2)" "unprognostic (4.06e-2)" "unprognostic (7.06e-3)" "unprognostic (1.02e-1)" "unprognostic (8.79e-3)" "unprognostic (8.85e-2)" "unprognostic (2.03e-1)" "unprognostic (1.51e-1)" "unprognostic (2.98e-2)" 0.4 5.3 0.0 0.3 0.0 0.1 8.7 0.3 0.6 18.5 0.0 0.1 0.5 1.2 0.9 51.0 3.4 2.7 0.3 0.1 0.0 2.7 0.7 3.4 0.0 0.0 0.0 0.2 11.6 7.0 0.4 7.3 0.0 1.5 0.1 0.5 24.8 3.4 1.3 219.1 0.3 0.1 0.0 0.1 0.5 0.3 0.0 0.8 0.8 0.0 41.1 9.9 36.5 0.0 202.5 66.7 0.0 0.0 0.0 0.0 54.2 2.9 1.8 15.3 4.6 4.5 85.9 0.0 94.4 2.3 99.4 98.5 0.0 1.3 5.3 0.4 0.0 0.0 99.4 2.4 10.1 0.1 0.1 1.1 11.9 3.5 23.0 70.2 23.2 0.0 0.0 0.1 5.4 287.3 0.2 0.1 0.4 58.5 10.1 0.2 79.4 3.0 87.1 35.7 24.5 1.3 50.1 127.7 1.2 5.6 24.1 1.0 13.5 0.3 174.4 0.2 71.6 0.1 0.3 0.5 18.0 7.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 6.2 3.9 4.4 0.0 0.0 14.7 4.6 0.4 10.0 9.4 11.0 0.0 25.9 0.1 0.3 0.0 63.0 0.9 33.0 3.7 0.5 0.0 0.0 0.1 20.4 3.4 0.4 0.0 33.5 0.0 0.6 0.0 0.0 2.0 0.0 0.0 0.1 12.2 0.0 1.6 0.5 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 48.4 0.0 0.0 0.0 4.8 0.1 1.8 21.7 0.0 0.0 0.4 2.2 0.1 0.0 2.9 37.4 58.3 0.3 0.3 0.3 8.5 MAFIP "FLJ00219, FLJ35473, FLJ39633, MIP, pp5644, TEKT4P4" ENSG00000274847 "MAFF interacting protein (pseudogene)" Unmapped 53594-115055 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 4.0;Endometrial ciliated cells: 3.9;Endometrial stromal cells: 3.8;Glandular and luminal cells: 5.2;Proximal tubular cells: 3.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA053929 Uncertain "Intermediate filaments" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Intermediate filaments" "HPA053929: AB_2682314" 3.8 5.5 6.3 1.5 6.6 0.9 1.1 6.9 8.2 1.6 6.4 1.2 1.6 1.5 0.8 2.7 1.9 2.3 2.0 6.6 6.7 2.0 1.8 1.9 3.7 7.2 6.5 3.6 2.7 1.5 1.4 7.1 2.3 0.5 1.4 4.1 1.4 1.8 0.7 2.3 2.1 6.9 3.2 0.8 1.2 6.6 0.4 1.5 1.8 1.3 1.9 7.2 0.0 2.9 0.0 0.9 0.0 0.0 2.0 3.9 1.7 1.1 1.6 6.5 7.5 0.0 6.4 5.1 3.0 0.9 2.3 3.7 0.5 0.0 2.5 1.7 3.0 6.0 0.1 0.0 5.7 0.6 5.7 2.0 0.0 4.7 3.8 0.0 7.6 1.8 2.4 7.8 6.0 0.7 0.0 3.5 1.1 0.0 3.6 1.3 4.1 0.5 1.9 4.2 0.0 2.3 3.6 0.7 5.7 0.1 8.6 2.1 3.4 0.9 2.7 5.6 2.1 0.0 8.7 0.0 1.2 2.1 1.5 1.2 1.3 2.1 0.9 2.1 1.2 1.1 2.5 2.3 1.6 1.6 0.1 1.9 0.9 5.0 2.0 1.4 6.3 6.6 6.9 8.2 6.6 6.7 7.2 6.5 7.1 6.9 6.6 7.2 4.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.0 1.4 0.4 0.0 0.0 0.0 0.0 1.4 0.9 0.0 0.0 0.7 0.0 3.9 3.8 1.2 0.0 0.0 0.0 1.1 0.7 1.1 0.0 5.2 0.0 1.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.9 0.0 0.0 3.3 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.2 0.4 0.3 0.0 0.0 MARVELD3 MRVLDC3 ENSG00000140832 "MARVEL domain containing 3" Q96A59 16 71626161-71642114 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 33.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 150.1;Intestinal goblet cells: 68.2;Paneth cells: 102.9;Proximal enterocytes: 199.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "basophil: 1.8" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "A-431: 21.7;BEWO: 30.9;CACO-2: 23.6;CAPAN-2: 22.5;HaCaT: 21.4;MCF7: 40.8;RT4: 18.8;SK-BR-3: 18.5;T-47d: 26.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043514, HPA045471" Approved "Vesicles,Intermediate filaments" No NA "Cluster 17: Basophils - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 45: Enterocytes - Digestion" Vesicles "Intermediate filaments" "HPA043514: AB_10959475, HPA045471: " "unprognostic (1.18e-1)" "unprognostic (3.92e-1)" "unprognostic (9.92e-2)" "unprognostic (5.56e-2)" "unprognostic (1.03e-1)" "unprognostic (6.16e-3)" "unprognostic (2.04e-1)" "unprognostic (3.22e-2)" "unprognostic (2.54e-1)" "unprognostic (8.75e-3)" "unprognostic (3.29e-1)" "unprognostic (5.16e-2)" "prognostic favorable (6.80e-10)" "unprognostic (2.63e-3)" "unprognostic (4.76e-1)" "unprognostic (3.59e-2)" "unprognostic (2.43e-1)" 0.2 0.3 0.5 3.1 0.6 0.6 6.2 1.8 0.9 4.0 6.5 23.6 31.1 1.8 7.3 4.2 4.2 4.8 0.3 1.1 0.5 12.9 5.3 2.4 0.5 0.4 0.5 0.5 17.1 12.5 1.0 5.7 0.5 6.0 18.7 2.1 11.6 2.5 0.8 3.3 33.1 0.6 0.1 0.4 2.8 0.9 0.5 0.9 3.9 0.0 1.7 3.8 2.5 0.9 21.7 0.7 0.5 0.9 0.0 0.1 30.9 0.0 0.0 0.0 0.0 23.6 22.5 0.2 2.3 0.0 0.1 21.4 1.9 10.3 0.1 0.0 12.1 0.0 0.4 6.2 0.0 0.1 0.2 0.9 12.5 0.1 0.2 0.1 0.0 0.1 0.3 0.1 0.0 40.8 0.2 0.3 3.5 13.4 0.2 0.0 0.1 8.8 0.3 18.8 3.7 0.2 0.4 18.5 0.0 2.4 26.3 0.3 0.0 0.0 0.4 0.4 0.2 0.2 0.3 0.1 0.2 0.2 0.2 1.8 0.2 0.2 0.2 0.1 0.1 0.2 0.2 0.2 0.1 0.4 0.2 0.2 1.2 0.4 0.1 0.3 0.2 0.1 0.5 0.6 1.8 0.9 1.1 0.5 0.4 0.5 0.5 0.1 0.5 0.9 0.3 9.6 8.4 0.3 0.8 7.9 28.7 9.6 22.8 7.0 25.4 10.7 0.6 40.0 17.9 9.2 0.0 36.5 1.5 150.1 1.9 29.8 4.4 14.2 1.5 1.0 61.5 0.0 0.6 33.7 2.5 1.5 6.1 19.4 0.0 3.8 0.4 9.1 3.1 0.0 0.6 68.2 14.2 1.0 1.0 3.3 0.3 1.2 0.0 0.0 0.8 1.0 0.0 0.0 0.6 26.3 102.9 0.7 0.0 38.4 199.3 27.6 17.4 19.6 0.0 4.1 1.6 9.6 5.0 19.6 3.7 4.8 1.4 0.0 61.3 44.3 MMP14 MT1-MMP ENSG00000157227 "Matrix metallopeptidase 14" P50281 14 22836560-22849041 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 244.0;Pancreatic endocrine cells: 144.7;Syncytiotrophoblasts: 122.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 923.8;HHSteC: 794.2;HSkMC: 887.0;hTERT-RPE1: 925.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009918, HPA051432" Approved Approved "Intermediate filaments,Cytosol" No No 1400000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "Intermediate filaments" "CAB009918: AB_2250767, HPA051432: AB_2681484" "unprognostic (1.34e-1)" "unprognostic (1.37e-1)" "unprognostic (1.11e-2)" "unprognostic (2.81e-1)" "unprognostic (4.28e-2)" "unprognostic (1.12e-2)" "unprognostic (3.05e-3)" "unprognostic (5.91e-3)" "unprognostic (1.95e-1)" "prognostic unfavorable (9.48e-4)" "unprognostic (3.82e-3)" "unprognostic (7.31e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (5.02e-2)" "unprognostic (6.69e-2)" "unprognostic (1.00e-2)" "unprognostic (3.41e-3)" 151.5 31.7 5.6 59.9 5.0 1.6 101.5 5.7 7.5 181.3 61.8 77.2 39.5 167.3 19.0 92.1 82.1 148.2 41.3 6.6 7.2 35.9 13.2 91.8 24.8 11.9 8.4 90.2 36.0 65.3 14.2 118.9 9.2 59.9 36.6 9.6 78.1 45.5 18.8 127.5 69.4 106.0 7.3 30.8 57.7 11.7 13.2 13.0 50.0 16.1 30.8 103.9 111.1 10.6 90.6 1.2 26.3 2.0 923.8 651.6 455.9 270.1 606.4 93.3 158.5 21.3 337.4 0.9 146.4 301.9 24.6 216.3 0.3 262.2 99.7 1.1 0.6 37.2 1.7 5.0 794.2 0.4 1.3 887.0 148.7 334.7 288.3 925.5 492.9 0.6 0.8 2.1 185.1 0.7 0.4 79.4 14.7 17.7 52.4 2.1 96.0 0.2 61.4 148.1 0.3 0.6 187.3 0.3 574.2 104.4 1.0 79.5 436.8 724.9 53.7 198.2 329.6 0.8 1.6 1.1 410.9 0.6 396.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 5.0 5.7 7.5 6.6 7.2 11.9 8.4 9.2 7.3 13.2 10.6 13.9 12.8 3.0 2.0 3.4 34.0 23.4 105.4 39.3 0.0 14.1 17.5 4.7 50.1 42.2 7.3 0.0 105.6 0.3 19.9 11.7 63.0 0.4 16.1 81.6 35.2 7.8 0.0 0.0 28.7 244.0 84.0 25.5 14.8 3.8 9.3 32.9 2.7 89.5 0.0 0.0 24.5 34.6 20.2 32.7 2.4 72.1 38.0 37.4 4.7 21.5 14.3 0.0 0.5 0.1 144.7 33.0 54.9 0.3 21.8 19.9 11.7 46.8 0.8 39.5 11.1 73.9 0.8 0.8 33.7 34.2 122.7 2.5 15.6 18.6 37.9 NEFL "CMT1F, CMT2E, NF68, NFL, PPP1R110" ENSG00000277586 "Neurofilament light" P07196 8 24950955-24956721 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 675.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 32.7;Distal tubular cells: 103.7;Enteroendocrine cells: 33.3;Excitatory neurons: 64.6;Horizontal cells: 30.3;Rod photoreceptor cells: 110.0" "Cancer enhanced" "Detected in many" "renal cancer: 24.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "memory CD4 T-cell: 11.2" "Lineage enriched" "Detected in single" 113 "T-cells: 11.2" "Group enriched" "Detected in some" 4 "HEK 293: 456.2;PC-3: 145.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014850, HPA015021" Enhanced Supported Approved "Nucleoplasm,Intermediate filaments,Midbody" Yes NA 200000 "Cluster 32: T-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Intermediate filaments" Midbody "HPA014850: AB_1854397, HPA015021: AB_2669135" "unprognostic (7.63e-2)" "unprognostic (1.36e-2)" "unprognostic (9.53e-2)" "unprognostic (6.81e-2)" "unprognostic (2.82e-2)" "unprognostic (6.69e-2)" "unprognostic (3.69e-2)" "unprognostic (3.78e-3)" "unprognostic (3.06e-1)" "unprognostic (1.60e-1)" "unprognostic (1.46e-2)" "unprognostic (1.94e-1)" "prognostic unfavorable (4.91e-4)" "unprognostic (5.76e-3)" "unprognostic (7.88e-2)" "unprognostic (3.97e-3)" "unprognostic (3.17e-3)" 0.1 18.0 35.4 1.3 36.7 0.0 0.0 103.6 675.9 2.0 0.0 2.5 0.6 0.1 0.3 5.4 1.3 0.1 0.1 50.9 75.6 5.0 0.0 0.0 0.1 425.7 41.1 0.2 0.2 0.1 4.0 0.0 231.3 1.8 1.5 89.5 0.0 15.6 0.0 0.9 1.9 1.1 33.9 0.2 0.8 1.7 216.1 12.7 0.7 0.1 0.3 0.0 1.4 184.0 0.0 0.6 68.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.7 0.0 0.6 0.0 0.0 456.2 0.0 0.0 0.0 21.6 0.0 1.0 8.3 2.0 0.1 1.4 0.0 0.0 0.0 0.0 0.1 2.2 0.0 0.0 0.0 18.8 0.0 145.4 0.0 0.0 0.0 31.7 4.2 30.9 31.6 11.2 0.0 1.9 2.2 0.0 0.0 0.0 2.2 31.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 4.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 11.2 1.2 0.0 0.0 2.3 0.1 0.0 0.0 0.0 0.0 0.2 1.5 35.4 36.7 103.6 675.9 50.9 75.6 425.7 41.1 231.3 33.9 216.1 184.0 0.1 0.0 0.0 23.2 0.0 0.0 0.0 0.0 0.6 32.7 0.0 0.0 3.2 0.0 0.0 0.0 8.4 0.0 0.1 0.1 103.7 0.1 0.4 0.1 0.3 3.7 33.3 0.0 64.6 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 30.3 29.1 0.1 0.0 0.0 0.0 0.7 0.0 0.2 0.0 27.2 0.1 27.8 0.0 14.6 18.4 0.0 0.1 9.4 0.0 0.0 0.0 0.2 0.0 110.0 0.0 0.1 0.2 0.0 13.2 1.5 0.0 0.0 1.6 1.4 0.0 0.0 NEFM "NEF3, NF-M, NFM" ENSG00000104722 "Neurofilament medium" P07197 8 24913758-24919098 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 689.9" "Cell type enhanced" "Detected in many" "Early spermatids: 92.6;Excitatory neurons: 46.6;Late spermatids: 114.6;Rod photoreceptor cells: 69.1;Spermatocytes: 43.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 25 "HEK 293: 3890.8" "CAB010900, CAB012976, HPA022845, HPA023138" Enhanced Enhanced "Intermediate filaments" Yes NA 220000 "Cluster 70: Brain - Nervous system development" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 46: Photoreceptor cells - Phototransduction" "Intermediate filaments" "CAB010900: AB_477261, CAB012976: AB_2533154, HPA022845: AB_1854399, HPA023138: AB_1854398" "unprognostic (1.41e-2)" "unprognostic (1.83e-1)" "unprognostic (2.59e-2)" "unprognostic (9.38e-2)" "unprognostic (5.17e-2)" "unprognostic (6.32e-3)" "unprognostic (6.10e-3)" "unprognostic (2.57e-1)" "unprognostic (8.55e-3)" "unprognostic (2.95e-2)" "unprognostic (1.84e-1)" "unprognostic (1.69e-2)" "unprognostic (1.38e-2)" "unprognostic (1.92e-1)" "unprognostic (4.76e-2)" "unprognostic (2.61e-2)" 0.3 19.5 61.1 0.9 27.9 0.0 0.1 150.0 689.9 9.6 0.0 2.8 0.1 4.0 0.0 4.0 5.3 0.2 0.2 57.7 54.0 1.9 0.1 0.2 0.1 610.3 89.1 1.7 2.0 0.0 17.9 0.2 487.1 1.5 0.7 90.8 0.3 27.6 1.7 0.6 1.3 2.5 86.8 0.1 0.9 18.9 430.5 1.7 0.1 0.7 0.5 0.4 6.5 203.6 0.0 0.0 154.3 0.0 0.0 0.0 0.0 2.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3890.8 0.0 0.0 0.0 79.4 0.0 0.1 2.4 0.1 0.6 0.0 0.0 0.0 0.7 0.0 0.2 5.9 0.0 0.0 0.0 30.1 0.0 0.0 0.0 0.0 0.0 0.7 0.1 3.7 32.6 0.0 0.0 0.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.1 27.9 150.0 689.9 57.7 54.0 610.3 89.1 487.1 86.8 430.5 203.6 3.1 0.0 0.0 12.4 0.0 1.3 0.2 0.1 9.1 30.9 1.1 21.2 2.4 0.0 0.6 0.0 6.2 0.0 3.2 0.1 0.0 0.1 92.6 0.7 19.5 2.9 3.5 0.0 46.6 0.2 0.0 2.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 20.2 17.5 0.0 0.0 0.0 0.7 114.6 0.9 0.7 1.8 13.1 0.0 22.8 0.0 9.5 13.6 0.0 0.0 4.5 0.4 0.3 0.0 0.4 0.0 69.1 0.0 3.3 5.7 43.8 1.0 14.0 0.3 0.0 4.1 0.0 0.1 0.4 NES FLJ21841 ENSG00000132688 Nestin P48681 1 156668763-156677407 "Plasma proteins, Predicted intracellular proteins" Neurogenesis "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 161.6" "Group enriched" "Detected in many" 4 "Adipocytes: 102.2;Cardiomyocytes: 279.9;Endothelial cells: 105.5;Sertoli cells: 105.2;Smooth muscle cells: 70.5" "Cancer enhanced" "Detected in all" "glioma: 147.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 627.3;HUVEC TERT2: 321.5;LHCN-M2: 512.6;RH-30: 518.3;SuSa: 340.7;WM-115: 247.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005889, HPA006286, HPA007007, HPA026111, CAB058692" Enhanced Enhanced "Intermediate filaments" No No 100000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 12: NES - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Intermediate filaments" "CAB005889: AB_2251301, CAB058692: AB_2665584, HPA006286: AB_2667550, HPA007007: AB_1854381, HPA026111: AB_1854382" "unprognostic (7.73e-2)" "unprognostic (2.05e-1)" "unprognostic (2.80e-2)" "unprognostic (1.36e-1)" "unprognostic (6.37e-2)" "unprognostic (1.54e-1)" "unprognostic (1.08e-1)" "unprognostic (4.40e-2)" "unprognostic (7.56e-2)" "unprognostic (9.84e-2)" "unprognostic (4.49e-2)" "unprognostic (1.24e-1)" "prognostic unfavorable (8.02e-7)" "unprognostic (2.87e-1)" "unprognostic (2.48e-1)" "unprognostic (6.67e-2)" "unprognostic (8.11e-3)" 40.0 8.5 24.4 13.8 24.8 0.0 28.2 27.2 22.7 27.1 16.5 16.8 5.3 41.1 12.9 8.2 30.3 11.3 161.6 21.1 26.5 35.2 4.8 42.1 4.8 32.8 27.1 10.1 5.6 10.4 12.8 16.7 25.8 21.2 6.6 8.2 9.7 36.1 55.7 8.6 12.5 30.3 30.0 49.1 10.8 6.2 26.4 2.7 19.9 47.3 2.3 24.2 19.0 30.9 0.2 2.5 627.3 134.7 1.3 33.4 0.6 154.7 120.7 2.3 3.4 102.5 1.9 0.6 35.8 14.9 0.1 2.8 63.9 0.0 1.8 0.0 1.1 0.9 9.7 47.3 5.5 0.3 37.1 28.5 0.0 5.7 0.0 5.3 321.5 0.1 4.9 0.2 512.6 4.3 0.0 0.3 102.3 6.0 88.1 0.7 518.3 0.4 0.6 0.0 1.6 100.4 3.6 4.5 124.9 340.7 1.3 0.9 235.1 0.8 34.5 4.1 8.8 0.2 24.0 0.2 13.4 0.1 247.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.4 24.8 27.2 22.7 21.1 26.5 32.8 27.1 25.8 30.0 26.4 30.9 102.2 0.0 4.4 0.0 0.7 2.4 0.4 0.2 0.6 0.5 9.4 32.9 279.9 0.0 0.6 18.4 0.0 0.2 1.0 0.6 0.0 2.1 0.4 2.1 31.9 105.5 0.0 0.0 0.3 0.0 1.9 29.4 0.5 2.7 0.0 0.2 26.7 0.1 1.8 0.0 0.6 0.2 0.0 0.8 3.1 0.1 8.1 1.7 1.8 12.2 1.0 17.4 0.0 3.0 2.2 0.3 0.1 4.1 0.1 0.5 0.0 0.1 0.0 1.5 105.2 10.9 70.5 0.5 5.0 1.2 2.4 0.1 1.1 1.4 0.3 0.5 NOL9 "FLJ23323, Grc3, NET6" ENSG00000162408 "Nucleolar protein 9" Q5SY16 1 6521347-6554513 "Metabolic proteins, Predicted intracellular proteins" "rRNA processing" "Kinase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036347 Supported "Nucleoli,Intermediate filaments" NA NA "Cluster 30: Non-specific - Translation" "Cluster 2: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" Nucleoli "Intermediate filaments" "HPA036347: AB_2675076" "unprognostic (3.03e-1)" "unprognostic (4.93e-2)" "unprognostic (4.99e-2)" "unprognostic (3.14e-3)" "unprognostic (2.12e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (3.69e-5)" "unprognostic (2.48e-1)" "unprognostic (1.31e-1)" "unprognostic (8.90e-2)" "unprognostic (1.44e-3)" "unprognostic (2.32e-1)" "unprognostic (3.80e-2)" "unprognostic (3.32e-2)" "unprognostic (3.40e-1)" "unprognostic (3.54e-2)" "unprognostic (4.65e-2)" 3.8 4.6 4.5 3.5 5.0 7.5 3.7 4.9 5.6 4.7 1.9 5.0 2.4 5.0 3.6 4.7 4.3 2.3 4.5 6.2 4.2 4.4 5.3 3.2 5.2 3.3 3.8 4.8 6.0 3.4 4.0 3.0 3.8 4.1 3.1 4.3 3.6 3.1 7.0 6.0 4.8 3.9 2.7 8.8 4.5 3.7 4.6 3.8 3.4 4.5 5.1 4.5 3.8 4.0 6.4 9.1 5.0 15.2 6.6 4.0 5.4 6.3 4.1 6.4 6.8 12.6 8.6 17.9 7.3 7.1 5.5 8.3 10.2 8.6 10.9 7.3 5.5 12.2 14.7 9.9 6.6 10.4 6.4 5.8 2.6 13.6 11.8 3.7 7.6 7.8 14.3 7.3 6.6 11.2 10.2 9.2 6.9 5.0 8.7 12.7 11.7 8.3 5.1 5.8 9.7 4.4 9.7 12.1 8.1 5.1 7.9 4.8 10.0 10.1 8.1 7.2 10.6 6.1 6.2 31.9 9.4 11.4 4.9 3.5 1.9 1.6 3.1 1.9 3.2 2.9 4.5 2.9 1.3 3.7 4.6 3.8 1.2 1.7 3.2 3.5 3.2 1.2 4.5 5.0 4.9 5.6 6.2 4.2 3.3 3.8 3.8 2.7 4.6 4.0 15.0 19.2 19.5 9.4 16.2 15.4 6.9 6.9 10.8 17.1 9.8 13.2 15.0 11.5 7.4 7.3 14.6 14.8 17.3 6.7 15.6 8.9 6.0 13.7 19.7 15.2 6.7 11.6 18.9 8.6 12.6 15.3 11.7 15.6 5.1 18.3 14.3 13.2 9.1 10.1 18.5 10.9 4.1 13.8 7.3 17.0 9.6 8.6 1.8 10.3 13.4 8.1 12.3 13.0 20.1 9.0 6.2 12.8 17.9 7.3 7.6 10.7 9.0 18.2 0.0 22.6 12.7 11.7 21.5 16.0 14.8 12.7 17.3 19.1 13.2 7.3 NRAP ENSG00000197893 "Nebulin related anchoring protein" Q86VF7 10 113588714-113664070 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "skeletal muscle: 2363.9;tongue: 1144.8" "Cell type enriched" "Detected in some" 9 "Cardiomyocytes: 534.1" "Group enriched" "Detected in some" 7 "head and neck cancer: 8.2;prostate cancer: 3.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA037953, HPA037954, HPA075074" Enhanced Approved "Vesicles,Intermediate filaments,Cytosol" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Intermediate filaments" "Vesicles, Cytosol" "HPA037953: AB_2675755, HPA037954: AB_10672394, HPA075074: " "unprognostic (1.13e-1)" "unprognostic (2.95e-1)" "unprognostic (3.61e-2)" "unprognostic (2.05e-2)" "unprognostic (5.75e-2)" "unprognostic (1.97e-2)" "unprognostic (1.25e-2)" "unprognostic (3.03e-3)" "unprognostic (3.72e-2)" "unprognostic (4.20e-2)" "unprognostic (6.40e-2)" "unprognostic (2.88e-1)" "unprognostic (5.39e-4)" "unprognostic (8.21e-2)" "unprognostic (1.16e-1)" "unprognostic (3.16e-1)" 0.3 0.1 0.1 0.0 0.5 0.0 0.4 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 24.8 0.0 0.2 428.6 0.2 0.0 0.1 0.5 0.4 0.1 0.0 0.2 0.1 0.4 0.0 0.3 0.0 0.0 20.4 1.0 0.0 22.1 0.0 2363.9 0.8 0.1 0.0 0.0 0.1 0.3 0.6 0.3 0.0 0.4 1144.8 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.4 0.2 0.0 0.0 0.2 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.3 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.0 534.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 1.4 0.1 0.0 3.7 0.0 0.0 0.3 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 4.8 0.0 0.0 0.3 2.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 57.3 3.3 1.0 2.3 0.0 0.1 0.0 0.2 0.0 0.5 0.0 PAFAH1B3 ENSG00000079462 "Platelet activating factor acetylhydrolase 1b catalytic subunit 3" Q15102 19 42297033-42303546 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatogonia: 188.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035639 Uncertain Approved "Intermediate filaments" NA NA 290000 "Cluster 26: Non-specific - Mitochondria" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Intermediate filaments" "HPA035639: AB_10670163" "unprognostic (3.19e-1)" "unprognostic (5.38e-3)" "unprognostic (1.13e-1)" "unprognostic (5.99e-2)" "unprognostic (1.83e-1)" "unprognostic (2.09e-2)" "prognostic unfavorable (8.74e-4)" "unprognostic (1.73e-1)" "unprognostic (2.67e-1)" "unprognostic (6.36e-2)" "unprognostic (2.37e-1)" "unprognostic (7.67e-2)" "prognostic unfavorable (2.07e-4)" "unprognostic (2.68e-1)" "unprognostic (3.21e-2)" "unprognostic (4.56e-2)" "unprognostic (6.80e-3)" 8.3 23.5 34.7 12.4 35.4 27.9 13.7 36.5 44.1 18.9 31.3 16.8 12.4 13.8 12.9 28.1 14.8 10.8 4.6 35.1 39.9 21.8 7.9 9.2 17.0 32.2 33.1 18.3 18.1 13.8 21.2 5.9 34.4 15.2 12.1 13.0 17.0 6.3 13.5 13.6 14.7 7.5 32.0 16.0 15.9 23.7 42.9 37.6 9.3 5.2 18.3 14.1 16.6 32.5 111.9 200.2 127.5 135.8 2.6 6.7 38.1 27.9 39.2 91.9 94.4 67.7 94.7 70.0 34.8 35.0 63.7 37.1 58.9 75.2 38.3 105.7 77.0 85.8 52.7 91.8 19.3 54.4 90.3 19.9 33.9 56.5 26.3 50.7 41.3 152.5 58.5 81.9 67.9 162.5 124.2 42.4 70.3 138.3 0.2 90.0 47.9 62.0 76.4 117.7 144.8 109.9 44.6 89.4 47.0 40.4 111.4 62.1 22.3 74.8 98.5 6.7 77.3 38.0 84.9 60.6 41.3 87.4 65.8 23.2 27.5 15.7 23.4 22.3 31.2 38.3 32.8 26.7 51.1 48.2 43.3 30.6 3.4 18.2 12.0 27.8 58.1 21.0 34.7 35.4 36.5 44.1 35.1 39.9 32.2 33.1 34.4 32.0 42.9 32.5 18.8 16.0 11.2 3.6 26.1 28.2 45.7 82.7 46.1 26.5 67.9 83.2 2.3 30.0 41.6 33.1 14.6 38.6 13.2 39.1 80.3 112.9 16.7 30.4 12.4 24.4 58.9 53.0 3.0 55.3 44.9 21.7 38.7 33.1 27.9 71.4 17.9 10.3 62.7 11.8 5.4 54.0 87.5 28.2 33.5 27.0 13.7 21.8 46.2 1.0 18.2 33.7 11.3 3.0 3.6 81.5 36.1 9.1 37.3 31.0 30.9 63.7 35.0 19.8 0.0 3.6 52.6 5.6 188.8 59.0 17.8 13.5 24.6 46.2 74.3 58.9 PELI1 ENSG00000197329 "Pellino E3 ubiquitin protein ligase 1" Q96FA3 2 64092652-64144420 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "bone marrow: 228.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 224.1;Plasma cells: 318.8;Squamous epithelial cells: 208.0;Suprabasal keratinocytes: 217.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 76.9" "Group enriched" "Detected in all" 4 "granulocytes: 76.9;monocytes: 23.2" "Cell line enhanced" "Detected in many" "CACO-2: 58.8;U-698: 146.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053182 Approved Approved "Nucleoplasm,Nucleoli,Intermediate filaments" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Nucleoli, Intermediate filaments" "HPA053182: AB_2682072" "unprognostic (3.33e-2)" "unprognostic (3.43e-2)" "unprognostic (1.79e-2)" "prognostic unfavorable (5.33e-4)" "unprognostic (1.91e-2)" "unprognostic (3.12e-3)" "unprognostic (6.73e-3)" "unprognostic (8.01e-3)" "unprognostic (4.16e-2)" "unprognostic (3.52e-3)" "unprognostic (5.99e-3)" "unprognostic (3.33e-1)" "prognostic unfavorable (5.67e-6)" "unprognostic (6.72e-2)" "unprognostic (6.22e-2)" "unprognostic (8.88e-2)" "unprognostic (1.03e-1)" 27.6 7.9 10.2 28.1 14.4 228.5 25.7 11.9 13.5 17.9 9.2 18.6 17.6 17.3 8.6 42.9 12.7 26.1 11.8 13.8 11.2 10.6 13.5 31.0 24.7 12.2 11.2 5.5 9.3 37.9 15.8 15.6 12.2 8.9 20.1 5.1 18.9 7.7 7.1 29.7 23.2 13.9 12.6 21.8 18.1 10.7 10.9 28.3 9.7 10.0 29.0 22.4 23.7 15.6 3.6 2.8 36.5 24.6 4.2 3.2 8.3 4.8 5.4 4.3 6.8 58.8 4.1 48.3 11.3 1.7 1.6 5.8 11.1 10.5 8.6 12.2 8.9 4.4 1.7 9.5 12.4 4.8 8.3 4.2 8.1 6.4 21.6 4.5 24.3 18.2 2.7 11.7 3.7 0.3 10.6 6.9 23.8 11.1 1.7 13.2 12.6 28.1 17.7 10.8 16.7 23.3 3.6 5.5 12.9 11.3 3.0 3.3 17.5 4.0 5.7 4.0 7.1 27.0 2.8 146.7 2.1 4.3 10.9 15.0 15.6 15.0 0.9 14.1 1.7 8.5 4.8 1.9 5.4 6.6 5.6 2.5 76.9 3.0 23.2 0.5 11.6 6.6 10.2 14.4 11.9 13.5 13.8 11.2 12.2 11.2 12.2 12.6 10.9 15.6 94.5 28.9 49.2 4.6 84.4 224.1 74.6 48.2 105.9 1.7 60.9 50.3 5.7 15.7 52.0 5.5 0.0 1.7 16.9 57.9 1.9 5.3 10.6 34.6 26.4 52.1 25.7 3.4 23.4 26.7 8.6 24.5 75.4 58.7 15.2 6.3 37.5 7.5 22.8 3.3 19.1 23.4 30.5 67.6 103.7 11.2 1.5 107.0 112.1 119.9 30.6 5.5 3.1 82.9 67.9 20.9 45.9 1.9 318.8 44.7 32.7 9.6 43.6 2.0 0.0 10.1 51.9 8.4 9.6 208.0 217.5 4.0 49.4 3.2 32.4 145.8 PELI2 ENSG00000139946 "Pellino E3 ubiquitin protein ligase family member 2" Q9HAT8 14 56117814-56301524 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 114.3;Microglial cells: 100.2;Oligodendrocyte precursor cells: 150.8;Oligodendrocytes: 77.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 5.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 33.3;JURKAT: 43.8;MOLT-4: 39.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053182 Uncertain Approved "Nucleoplasm,Nucleoli,Intermediate filaments" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Nucleoli, Intermediate filaments" "HPA053182: AB_2682072" "unprognostic (3.26e-1)" "unprognostic (2.25e-1)" "unprognostic (9.21e-2)" "unprognostic (8.94e-3)" "unprognostic (1.57e-1)" "unprognostic (1.68e-1)" "unprognostic (2.53e-2)" "unprognostic (3.36e-3)" "unprognostic (1.81e-1)" "unprognostic (2.68e-2)" "unprognostic (1.18e-1)" "unprognostic (2.14e-1)" "prognostic favorable (1.53e-6)" "unprognostic (3.64e-1)" "unprognostic (2.15e-1)" "unprognostic (5.43e-2)" "unprognostic (2.22e-1)" 11.6 3.0 8.1 4.3 7.8 18.6 7.7 27.9 5.9 6.7 5.4 7.0 11.0 6.7 2.5 4.4 6.3 10.0 2.9 5.6 6.6 9.2 2.8 6.7 4.0 8.8 10.9 15.0 28.6 1.9 2.7 3.1 9.3 4.7 3.9 15.1 7.7 3.5 2.4 5.9 9.2 3.3 8.0 6.8 14.4 10.0 10.4 19.1 4.1 3.8 2.0 10.6 5.7 9.2 0.1 3.1 8.8 0.0 4.8 7.2 0.2 1.2 4.2 0.9 0.1 0.2 0.7 0.2 4.2 2.5 0.0 0.9 6.9 0.0 0.4 2.3 2.4 7.9 13.0 0.0 4.1 1.1 33.3 4.5 0.4 0.0 0.0 4.8 1.6 43.8 6.0 0.1 0.9 0.0 39.5 0.4 14.5 0.1 1.2 19.2 0.5 1.8 3.6 15.4 17.5 0.0 0.8 0.1 10.2 5.5 0.0 6.3 0.5 2.6 4.4 0.8 4.4 0.7 0.1 1.0 4.6 5.4 2.6 0.9 1.9 2.4 0.3 1.0 0.5 0.1 0.3 0.2 1.3 0.4 0.2 0.1 5.6 0.3 0.8 0.3 0.0 0.7 8.1 7.8 27.9 5.9 5.6 6.6 8.8 10.9 9.3 8.0 10.4 9.2 13.9 0.0 10.0 114.3 7.7 14.3 10.4 1.7 9.6 30.7 7.1 7.7 2.7 8.6 6.7 12.9 29.2 0.1 11.8 15.0 3.9 5.9 3.7 23.7 14.5 18.0 7.2 5.5 13.5 14.1 0.1 13.5 34.1 21.2 5.7 5.7 17.5 1.0 1.2 21.9 22.1 7.9 2.0 19.7 14.0 5.7 17.1 20.3 17.8 100.2 22.9 9.7 10.3 150.8 77.5 9.1 6.0 18.0 5.6 7.8 12.4 10.1 8.8 19.7 13.1 5.4 22.0 2.0 24.0 4.7 18.3 0.1 6.2 5.6 3.1 12.6 PGD ENSG00000142657 "Phosphogluconate dehydrogenase" P52209 1 10398592-10420511 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Gluconate utilization, Pentose shunt" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 400.2;esophagus: 572.4" "Cell type enhanced" "Detected in all" "monocytes: 214.9;Squamous epithelial cells: 496.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 1060.2;classical monocyte: 321.0;eosinophil: 1074.7;neutrophil: 332.6" "Group enriched" "Detected in all" 5 "granulocytes: 1074.7;monocytes: 321.0" "Cell line enhanced" "Detected in all" "A549: 1445.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031314, HPA031315" Enhanced Supported Approved "Intermediate filaments,Cytosol" No No 41000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments, Cytosol" "HPA031314: AB_10610278, HPA031315: AB_2673825" "unprognostic (4.65e-2)" "unprognostic (2.58e-1)" "unprognostic (8.65e-2)" "unprognostic (9.80e-2)" "unprognostic (1.31e-2)" "unprognostic (2.28e-1)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.90e-2)" "unprognostic (2.83e-1)" "unprognostic (1.40e-2)" "unprognostic (4.92e-1)" "unprognostic (1.36e-1)" "unprognostic (1.37e-3)" "unprognostic (1.43e-1)" "unprognostic (1.49e-1)" "unprognostic (2.43e-3)" "unprognostic (1.14e-1)" 115.8 51.0 49.5 59.8 49.2 400.2 89.0 52.9 49.3 75.9 52.5 52.9 91.6 23.1 41.9 572.4 30.0 94.2 34.3 47.4 54.3 53.2 81.3 88.5 38.1 57.0 54.6 35.7 32.0 52.7 43.8 47.4 55.4 30.4 46.3 49.1 133.7 22.9 34.7 50.0 70.7 35.0 49.7 110.4 61.4 68.3 59.2 53.6 71.8 28.2 73.8 61.8 126.9 52.0 191.5 1445.2 319.3 340.6 445.4 274.0 71.8 124.8 185.9 144.4 195.3 219.2 190.4 163.5 151.0 109.2 202.4 148.0 225.6 192.1 96.4 127.5 199.9 227.8 264.3 452.1 136.3 390.9 249.7 196.5 92.2 229.4 55.5 186.9 344.0 223.0 305.3 145.7 183.5 202.5 321.4 179.4 194.7 221.0 109.1 252.7 298.1 312.2 199.6 105.5 178.0 154.1 99.1 153.5 137.5 196.7 173.3 308.5 369.3 81.1 149.6 98.3 134.5 111.6 256.0 323.5 175.1 393.9 73.6 1060.2 321.0 1074.7 23.2 137.7 26.5 33.1 21.4 20.8 144.6 23.3 21.1 22.3 332.6 19.7 105.6 98.7 23.1 225.0 49.5 49.2 52.9 49.3 47.4 54.3 57.0 54.6 55.4 49.7 59.2 52.0 7.4 19.2 35.0 11.8 24.9 13.0 30.8 78.0 70.6 7.8 30.4 18.5 11.0 50.1 73.2 20.2 18.8 134.6 29.8 24.3 52.8 52.1 10.9 17.8 18.6 22.6 23.4 55.7 8.6 40.3 40.7 37.5 41.8 24.5 25.9 53.9 16.1 66.2 134.6 1.7 12.6 30.2 59.0 163.8 30.9 13.4 17.1 150.9 17.8 4.7 214.9 16.5 10.3 13.6 9.0 38.7 26.7 10.5 41.9 43.5 66.6 55.1 46.2 20.2 19.7 23.4 21.5 41.5 38.4 496.0 16.6 81.3 19.4 27.3 51.7 76.1 PJA2 "KIAA0438, Neurodap1, RNF131" ENSG00000198961 "Praja ring finger ubiquitin ligase 2" O43164 5 109334713-109409974 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040347, HPA057636" Supported Enhanced "Intermediate filaments" No No "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 43: Cardiomyocytes - Nuclear processes" "Intermediate filaments" "HPA040347: AB_10795631, HPA057636: AB_2683485" "unprognostic (5.78e-2)" "unprognostic (1.25e-1)" "unprognostic (5.48e-3)" "unprognostic (1.17e-1)" "unprognostic (2.99e-1)" "unprognostic (7.83e-2)" "unprognostic (2.83e-1)" "unprognostic (4.33e-2)" "unprognostic (4.84e-2)" "prognostic unfavorable (8.02e-4)" "unprognostic (4.46e-2)" "unprognostic (6.03e-2)" "unprognostic (5.64e-3)" "unprognostic (1.47e-3)" "unprognostic (5.94e-2)" "unprognostic (7.59e-2)" "unprognostic (1.00e-2)" 59.3 67.9 63.3 44.4 72.9 87.9 57.0 44.9 89.8 68.9 22.1 56.1 33.4 74.5 62.2 50.8 46.2 48.3 65.8 78.6 77.0 61.1 77.3 51.4 41.4 52.6 52.1 87.8 38.8 88.1 36.8 58.2 56.2 78.4 52.5 64.2 49.2 91.9 39.0 30.6 40.6 77.1 58.9 54.7 33.1 47.0 58.6 53.8 92.1 54.2 44.6 53.7 36.9 68.9 36.0 24.6 96.2 74.6 93.4 101.3 52.4 57.9 86.5 44.6 72.6 22.9 47.6 46.0 78.1 111.8 71.8 20.5 57.0 71.3 81.1 39.5 21.7 53.5 47.4 31.1 66.2 40.2 75.8 70.4 58.1 59.7 85.1 80.0 72.4 40.8 37.2 84.0 73.0 21.9 48.8 36.9 19.2 21.9 16.3 31.1 84.6 77.5 69.5 31.9 18.4 47.1 59.8 21.5 70.5 64.2 48.6 58.7 84.6 63.4 30.7 58.8 27.5 56.4 51.6 53.5 66.8 54.8 42.6 32.9 19.2 29.3 14.4 19.7 14.4 16.5 14.1 13.4 19.3 11.7 18.0 13.4 49.0 17.8 27.7 8.0 20.5 18.5 63.3 72.9 44.9 89.8 78.6 77.0 52.6 52.1 56.2 58.9 58.6 68.9 85.2 67.3 58.4 71.2 76.9 63.5 56.2 59.8 58.1 102.1 53.0 58.5 127.5 51.5 51.7 57.0 62.6 24.1 78.2 85.9 49.0 40.8 22.5 42.8 97.5 70.3 67.6 32.1 159.0 33.3 31.0 86.7 32.1 68.2 47.5 99.3 70.6 94.8 54.5 77.4 126.0 53.1 36.7 91.5 78.5 20.7 85.1 77.1 60.5 66.5 73.4 93.0 68.0 60.8 111.6 30.9 30.4 92.6 72.0 59.2 46.8 58.7 48.4 91.3 78.9 105.0 110.1 73.4 42.9 43.7 58.2 26.3 68.7 61.6 39.3 44.0 PKN2 "Pak-2, PRK2, PRKCL2, STK7" ENSG00000065243 "Protein kinase N2" Q16513 1 88684222-88836255 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell adhesion, Cell cycle, Cell division, Cilium biogenesis/degradation, Host-virus interaction, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 80.5" "Lineage enriched" "Detected in all" 8 "granulocytes: 80.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034861, HPA057913" Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Intermediate filaments,Centrosome,Cytosol" Yes No "Cluster 1: Neutrophils - Mixed function" "Cluster 34: Non-specific - Transcription" "Cluster 15: RT4 - Unknown function" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Intermediate filaments" "Nuclear bodies, Plasma membrane, Centrosome, Cytosol" "HPA034861: AB_2674363, HPA057913: AB_2732617" "unprognostic (7.52e-2)" "unprognostic (1.46e-1)" "prognostic favorable (5.67e-4)" "unprognostic (5.95e-2)" "unprognostic (3.39e-2)" "unprognostic (2.51e-2)" "unprognostic (4.64e-3)" "unprognostic (1.38e-1)" "unprognostic (4.43e-2)" "unprognostic (1.27e-2)" "unprognostic (2.90e-3)" "unprognostic (1.23e-1)" "unprognostic (1.51e-2)" "unprognostic (5.98e-2)" "unprognostic (2.38e-1)" "unprognostic (1.01e-2)" "unprognostic (1.99e-1)" 19.3 16.5 9.3 17.6 14.2 48.7 24.1 20.7 10.9 16.4 17.0 23.9 30.5 23.6 25.0 24.7 18.1 17.1 14.1 9.5 9.7 16.9 20.5 20.4 18.2 12.3 10.4 31.2 15.5 22.3 10.1 24.7 12.7 20.3 30.0 26.7 16.3 15.4 9.8 20.3 30.8 18.5 10.1 19.0 20.9 10.5 12.6 17.8 26.1 13.4 17.4 21.3 15.4 17.6 61.1 23.8 45.2 27.3 29.8 33.6 29.6 35.3 32.2 38.5 39.8 25.3 42.5 23.9 41.0 33.6 47.3 46.7 44.7 26.6 52.4 8.6 33.0 17.7 49.3 21.4 26.2 17.6 5.1 27.7 27.1 30.2 36.3 30.6 44.7 18.6 29.9 16.8 42.2 12.2 20.5 15.2 22.8 23.1 27.1 19.3 68.8 9.8 34.3 117.9 22.0 14.5 52.7 29.8 45.7 33.9 22.5 15.7 42.2 32.5 29.2 42.1 37.2 9.2 8.6 16.6 13.6 17.1 12.6 15.3 9.9 16.6 5.7 5.9 5.1 8.0 5.1 5.3 5.0 9.3 6.6 5.6 80.5 3.5 8.0 8.6 4.6 2.7 9.3 14.2 20.7 10.9 9.5 9.7 12.3 10.4 12.7 10.1 12.6 17.6 104.7 41.7 57.8 102.5 52.5 48.4 44.3 33.3 75.1 85.4 60.2 67.9 50.8 38.6 47.9 69.9 89.6 42.9 48.1 101.5 11.7 61.2 2.6 63.7 68.7 59.5 44.3 57.7 134.2 60.7 33.1 53.1 85.6 84.6 15.8 107.0 47.5 39.4 24.2 65.6 130.8 64.3 32.6 35.8 27.9 6.6 54.3 44.9 32.0 178.0 57.3 50.5 22.6 117.1 146.4 77.6 98.1 48.2 54.8 64.7 84.0 26.7 49.1 150.5 39.5 62.8 55.5 43.6 34.6 83.0 52.4 37.4 44.8 90.2 65.0 124.2 POLR1A "DKFZP586M0122, FLJ21915, RPA1, RPA190, RPO1-4" ENSG00000068654 "RNA polymerase I subunit A" O95602 2 86020216-86106155 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Nucleotidyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010145, HPA031513, HPA049700" Supported Enhanced "Nucleoplasm,Nucleoli fibrillar center,Intermediate filaments" No No "Cluster 7: Monocytes - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nucleoli fibrillar center" "Nucleoplasm, Intermediate filaments" "CAB010145: AB_675814, HPA031513: AB_2673916, HPA049700: AB_2680856" "unprognostic (1.22e-1)" "unprognostic (1.82e-2)" "unprognostic (1.55e-1)" "unprognostic (2.46e-2)" "unprognostic (1.32e-1)" "unprognostic (1.93e-1)" "prognostic unfavorable (3.70e-9)" "unprognostic (1.06e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (3.37e-4)" "unprognostic (4.31e-2)" "unprognostic (4.56e-2)" "unprognostic (3.27e-1)" "unprognostic (2.20e-3)" "unprognostic (1.94e-1)" "prognostic unfavorable (8.41e-4)" "unprognostic (7.20e-2)" 5.4 5.7 3.7 5.8 4.0 4.9 4.5 3.1 4.7 4.9 4.0 4.9 4.1 8.2 3.0 6.0 5.2 2.9 5.8 3.9 3.6 4.6 5.0 4.0 4.6 3.4 3.6 5.2 5.2 7.1 4.9 5.0 3.3 4.5 5.0 3.5 3.9 5.1 10.8 5.5 3.8 6.9 2.7 3.8 4.5 6.2 4.4 6.2 4.5 7.4 4.9 5.2 4.2 4.3 18.5 41.1 18.0 34.7 17.2 13.7 25.9 16.6 10.9 23.2 14.4 51.9 14.2 41.9 17.2 17.0 22.7 20.9 46.6 24.4 20.6 17.6 24.0 36.2 18.0 35.1 12.1 34.8 18.7 10.5 15.0 34.6 26.7 8.8 18.2 19.0 48.8 10.3 16.2 16.4 25.8 15.1 32.7 24.4 26.8 30.7 39.5 19.6 10.5 29.7 27.7 14.6 18.3 23.8 12.7 12.3 14.0 12.0 29.3 28.0 22.2 24.3 33.8 14.5 15.3 35.7 14.6 29.3 25.3 0.5 0.4 0.0 0.7 0.6 0.9 0.5 0.3 0.6 0.4 0.6 0.3 0.4 0.1 0.5 0.5 0.7 0.1 0.4 3.7 4.0 3.1 4.7 3.9 3.6 3.4 3.6 3.3 2.7 4.4 4.3 4.9 3.2 9.1 13.4 8.8 4.2 4.9 5.3 12.0 12.4 6.2 5.5 11.1 8.6 4.7 9.2 16.7 6.3 7.2 5.1 3.9 6.0 3.0 5.4 13.8 6.5 9.6 10.9 19.7 4.9 5.4 7.7 8.2 6.9 6.3 11.0 4.2 8.3 12.5 11.8 18.1 6.7 2.0 3.1 3.5 1.7 6.2 5.5 5.4 6.5 3.3 4.2 6.2 20.1 18.2 6.6 3.0 5.3 10.1 9.1 3.5 3.4 5.2 9.7 0.0 14.3 6.2 5.0 7.2 13.4 2.7 3.8 7.5 12.4 10.4 4.0 PTPN18 BDP1 ENSG00000072135 "Protein tyrosine phosphatase non-receptor type 18" Q99952 2 130356045-130375405 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Macrophages: 143.4;NK-cells: 148.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 63.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB012174, HPA053367" Uncertain Approved "Intermediate filaments" NA NA 270000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" "Intermediate filaments" "CAB012174: AB_2173224, HPA053367: AB_2732579" "unprognostic (3.11e-3)" "unprognostic (2.89e-3)" "unprognostic (1.67e-3)" "unprognostic (1.73e-3)" "unprognostic (5.81e-3)" "unprognostic (3.08e-3)" "unprognostic (2.49e-2)" "unprognostic (1.28e-2)" "unprognostic (4.65e-1)" "unprognostic (2.10e-2)" "unprognostic (7.33e-2)" "unprognostic (5.65e-2)" "unprognostic (4.52e-2)" "unprognostic (1.00e-2)" "unprognostic (3.60e-1)" "unprognostic (1.05e-1)" "unprognostic (5.85e-3)" 22.3 12.3 19.6 23.2 19.4 28.2 21.5 21.7 21.4 21.2 18.4 35.3 21.7 15.7 6.1 17.8 19.6 14.8 15.3 18.8 19.1 25.4 37.8 22.0 42.7 21.0 19.6 12.5 34.6 9.5 19.0 12.2 20.1 33.3 24.7 6.4 31.9 13.2 7.5 12.7 39.4 13.3 18.7 63.8 27.0 4.6 20.0 11.1 20.0 7.5 48.6 18.8 18.9 19.6 12.4 8.3 3.2 16.2 19.7 13.5 32.9 6.2 5.6 7.9 8.8 16.4 18.5 46.4 6.2 15.2 3.7 13.8 14.3 14.1 7.6 21.1 8.0 16.9 9.8 19.5 10.2 16.6 44.5 16.0 11.4 8.7 12.0 1.7 15.2 10.1 16.1 34.2 15.4 24.3 3.1 28.4 3.3 26.6 8.6 28.4 9.5 63.0 15.9 7.5 20.6 5.4 10.9 38.6 18.7 3.1 13.2 24.1 14.4 11.2 12.6 6.2 5.9 5.6 1.6 44.5 17.1 14.9 12.4 8.4 7.8 6.7 6.4 11.2 4.0 7.3 4.2 6.1 6.9 5.1 2.6 5.1 4.8 3.1 19.4 7.5 6.0 10.7 19.6 19.4 21.7 21.4 18.8 19.1 21.0 19.6 20.1 18.7 20.0 19.6 37.2 28.9 23.9 12.1 43.6 6.5 28.8 15.9 12.0 13.4 52.0 53.5 9.0 18.6 17.5 36.8 4.2 15.6 85.6 75.9 54.8 19.0 0.9 20.6 14.0 30.7 48.6 32.4 18.2 45.4 30.5 16.3 65.2 24.0 35.5 12.2 25.7 21.1 92.4 10.1 18.6 52.5 30.5 113.6 35.9 1.6 19.0 143.4 33.8 35.6 65.2 18.4 148.3 5.5 6.1 29.0 66.9 11.3 23.5 37.9 41.3 37.3 20.5 11.6 19.7 15.1 21.5 2.6 6.0 19.4 5.8 11.5 39.3 16.2 47.5 28.9 QTRT2 "FLJ12960, QTRTD1" ENSG00000151576 "Queuine tRNA-ribosyltransferase accessory subunit 2" Q9H974 3 114005833-114088422 "Metabolic proteins, Predicted intracellular proteins" "tRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 19.2;Alveolar cells type 2: 20.3;Endometrial stromal cells: 19.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036827, HPA036828" Uncertain Approved "Nucleoplasm,Intermediate filaments" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Intermediate filaments" "HPA036827: AB_2675336, HPA036828: AB_10696788" "unprognostic (2.22e-1)" "unprognostic (1.11e-1)" "unprognostic (6.71e-3)" "unprognostic (1.01e-3)" "unprognostic (8.57e-2)" "unprognostic (4.41e-1)" "unprognostic (5.82e-3)" "unprognostic (3.58e-1)" "unprognostic (1.35e-1)" "unprognostic (6.94e-2)" "unprognostic (6.48e-3)" "prognostic unfavorable (6.95e-4)" "unprognostic (1.44e-1)" "unprognostic (8.74e-2)" "unprognostic (2.65e-2)" "unprognostic (1.98e-1)" "unprognostic (1.18e-3)" 6.9 6.5 3.6 9.4 3.9 11.2 10.1 3.2 4.0 7.4 9.0 8.4 7.7 8.4 6.4 7.0 7.5 5.3 3.4 4.3 3.6 7.5 7.2 8.6 12.0 3.8 3.6 8.1 6.7 7.3 4.4 8.5 3.8 6.9 8.9 11.3 5.9 5.9 3.8 8.2 7.6 7.4 3.4 11.8 6.9 7.1 3.7 7.7 8.9 3.9 11.6 9.6 5.2 4.4 26.8 27.1 22.2 24.6 9.6 11.7 20.9 13.7 8.6 22.9 20.9 26.0 18.8 49.4 19.5 12.7 27.3 25.9 43.5 20.6 29.9 9.4 19.6 22.2 15.9 18.6 13.7 40.8 20.0 9.3 18.2 20.8 29.4 9.3 24.0 22.5 23.7 17.1 13.1 21.4 34.3 15.9 42.6 37.6 29.3 30.6 15.6 26.6 18.0 18.2 30.1 14.2 19.9 19.4 25.1 18.4 21.6 20.4 15.9 19.9 21.6 7.9 26.9 12.0 18.7 68.1 17.4 29.6 40.9 0.6 15.3 3.8 6.4 15.8 6.0 16.8 5.4 6.3 19.4 11.0 7.4 6.0 6.5 8.6 11.4 8.1 7.6 6.5 3.6 3.9 3.2 4.0 4.3 3.6 3.8 3.6 3.8 3.4 3.7 4.4 14.0 19.2 20.3 0.0 8.4 0.0 0.0 0.0 0.0 0.0 13.8 12.4 0.0 0.0 10.5 3.7 0.0 10.9 10.0 0.0 1.9 15.7 0.0 16.3 19.7 9.9 0.0 0.0 0.0 12.4 10.9 6.2 0.0 15.1 15.2 15.7 0.0 0.0 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 8.3 0.0 0.0 0.0 0.0 16.7 0.0 0.0 3.3 0.0 0.0 8.9 4.4 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 4.9 4.3 17.4 0.0 0.0 RAB3IP "FLJ22548, RABIN3, RABIN8" ENSG00000127328 "RAB3A interacting protein" Q96QF0 12 69738860-69823204 "Predicted intracellular proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Bipolar cells: 210.4;Early spermatids: 287.3;Late spermatids: 453.9;Oligodendrocyte precursor cells: 261.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 156.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039794 Uncertain Approved "Intermediate filaments" No No "Cluster 35: T-regs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" "Intermediate filaments" "HPA039794: AB_10960557" "unprognostic (4.38e-3)" "unprognostic (1.48e-1)" "unprognostic (6.66e-2)" "unprognostic (8.57e-2)" "unprognostic (3.30e-3)" "unprognostic (1.95e-1)" "unprognostic (1.75e-2)" "unprognostic (7.10e-2)" "unprognostic (2.12e-1)" "unprognostic (1.31e-1)" "unprognostic (1.16e-2)" "unprognostic (1.24e-1)" "prognostic favorable (5.68e-13)" "unprognostic (6.17e-2)" "unprognostic (1.20e-1)" "unprognostic (1.15e-1)" "unprognostic (3.37e-1)" 3.7 15.9 17.7 6.4 22.0 25.6 19.9 79.7 16.9 8.4 51.6 21.7 19.2 5.5 44.3 8.6 15.2 15.1 18.3 18.7 18.9 48.5 16.6 14.9 13.6 25.7 21.7 3.1 22.8 26.9 20.2 12.0 26.2 20.8 22.6 88.6 12.8 9.7 9.7 11.8 22.4 4.9 12.1 6.8 18.4 74.7 19.7 12.7 16.2 14.3 15.3 11.8 4.8 25.6 44.1 23.5 14.3 22.9 6.9 3.1 41.0 4.3 9.9 16.9 22.6 67.3 19.1 34.1 13.9 2.3 21.9 33.0 14.7 22.9 29.0 51.7 25.6 25.3 8.4 32.9 6.4 29.9 15.4 7.4 23.3 15.6 52.4 17.5 24.8 44.4 12.1 30.3 9.6 46.8 30.3 12.8 35.7 46.1 25.7 35.3 22.2 35.9 55.1 53.5 56.7 10.2 16.7 28.0 6.4 57.0 47.6 11.1 7.4 7.2 18.3 3.0 20.3 14.2 63.4 156.9 17.5 18.3 11.2 1.8 5.2 7.2 4.2 1.9 8.5 9.2 7.5 6.8 5.6 8.6 9.3 9.1 6.9 7.8 2.3 5.1 12.6 4.4 17.7 22.0 79.7 16.9 18.7 18.9 25.7 21.7 26.2 12.1 19.7 25.6 4.0 60.9 51.1 19.6 17.7 23.6 55.6 28.8 19.4 210.4 44.6 13.0 50.2 85.8 48.8 51.5 110.5 21.7 6.4 33.1 37.2 64.6 287.3 79.7 5.2 8.7 40.8 14.1 22.6 31.8 8.2 6.4 39.3 119.7 2.5 19.3 7.1 16.5 3.5 28.6 186.1 39.3 46.8 1.9 7.5 453.9 4.4 8.0 5.4 9.4 16.6 96.6 4.1 261.9 104.1 51.1 38.6 3.8 25.9 77.9 46.1 82.1 54.4 95.8 6.6 31.8 12.3 48.9 37.7 24.2 29.8 8.5 15.1 3.5 45.8 76.7 S100A8 "60B8AG, CAGA, CFAG, CGLA, MRP8, P8" ENSG00000143546 "S100 calcium binding protein A8" P05109 1 153390032-153391073 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Autophagy, Chemotaxis, Immunity, Inflammatory response, Innate immunity" Antimicrobial "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 35382.0;esophagus: 24565.6;vagina: 11166.4" "Group enriched" "Detected in many" 7 "Basal respiratory cells: 4126.5;Kupffer cells: 6348.0;Macrophages: 3758.3;monocytes: 6932.6;Squamous epithelial cells: 8480.1" "Cancer enhanced" "Detected in all" "cervical cancer: 2290.9;head and neck cancer: 2382.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 9 "classical monocyte: 26833.7;neutrophil: 52973.6" "Group enriched" "Detected in all" 9 "granulocytes: 52973.6;monocytes: 26833.7" "Group enriched" "Detected in some" 24 "hTCEpi: 241.8;SK-BR-3: 719.0;THP-1: 400.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB002791, HPA024372" Enhanced Supported "Intermediate filaments,Cytosol" "Secreted to blood" NA NA 10900000 370000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Intermediate filaments" Cytosol "CAB002791: , HPA024372: AB_1856536" "unprognostic (1.98e-1)" "unprognostic (1.13e-1)" "unprognostic (3.79e-2)" "unprognostic (1.58e-2)" "unprognostic (8.60e-3)" "unprognostic (9.26e-3)" "unprognostic (4.92e-2)" "unprognostic (1.32e-1)" "unprognostic (1.83e-1)" "unprognostic (6.13e-2)" "unprognostic (3.77e-2)" "unprognostic (2.24e-2)" "prognostic unfavorable (8.94e-7)" "unprognostic (1.17e-1)" "unprognostic (8.90e-2)" "unprognostic (8.27e-2)" "unprognostic (8.94e-3)" 582.3 54.3 41.7 1245.8 45.6 35382.0 70.0 43.4 88.0 5650.6 45.5 55.2 15.4 23.1 5.5 24565.6 236.1 99.0 121.1 40.9 42.7 103.0 176.7 1061.7 29.5 47.7 44.8 25.8 52.0 9.6 41.7 205.8 50.7 43.1 14.7 5.6 3988.2 5.0 48.5 267.3 47.7 430.2 44.2 3239.5 93.8 16.2 45.5 281.3 48.8 174.8 8952.6 561.9 11166.4 46.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 9.0 1.3 0.0 0.3 12.4 0.0 18.7 0.0 0.1 0.0 3.5 0.0 0.0 0.0 5.6 0.1 0.0 241.8 0.0 7.5 0.0 0.0 0.0 9.6 1.2 0.0 0.9 0.4 1.5 0.3 0.0 0.0 0.4 5.8 1.0 0.0 0.0 0.4 0.5 3.6 719.0 0.0 0.0 4.7 400.6 10.6 0.0 0.2 0.9 0.1 0.2 1.3 2.7 0.3 13.9 0.0 848.0 26833.7 3023.7 33.4 1999.2 49.2 57.2 21.8 18.2 4686.1 23.5 21.6 23.3 52973.6 27.1 493.1 188.1 37.1 24979.9 41.7 45.6 43.4 88.0 40.9 42.7 47.7 44.8 50.7 44.2 45.5 46.2 1.1 224.4 489.8 0.0 77.2 19.6 3.5 4126.5 50.7 0.0 13.2 3.9 10.0 70.1 817.0 14.7 0.0 5.8 67.1 0.3 0.0 1.0 210.7 0.5 0.6 33.1 0.0 143.5 0.0 0.9 8.5 61.3 1.1 0.5 227.1 0.1 76.1 54.6 417.5 0.0 0.0 0.2 207.5 6348.0 5.1 172.4 4.1 3758.3 0.0 0.0 6932.6 0.0 289.4 0.0 0.0 1.4 0.0 1.5 26.1 0.9 0.0 25.0 162.8 0.0 0.0 7.7 32.3 2.1 1.0 8480.1 113.2 6.7 91.4 0.0 0.0 31.3 SCN3B HSA243396 ENSG00000166257 "Sodium voltage-gated channel beta subunit 3" Q9NY72 11 123629187-123655244 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Atrial fibrillation, Brugada syndrome, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 54.2;pituitary gland: 28.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 31.6;Excitatory neurons: 58.8;Horizontal cells: 20.2;Inhibitory neurons: 35.7;Late spermatids: 31.3" "Cancer enhanced" "Detected in some" "glioma: 2.2" "Group enriched" "Detected in many" 8 "amygdala: 34.3;basal ganglia: 40.6;cerebral cortex: 49.7;hippocampal formation: 54.2;white matter: 15.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 1.8;GAMG: 1.8;hTCEpi: 5.8;RH-30: 2.0;SCLC-21H: 5.5;SH-SY5Y: 4.5" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "hippocampal formation: 166.1" HPA041707 Approved "Intermediate filaments,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Intermediate filaments" Cytosol "HPA041707: AB_2732493" "unprognostic (1.41e-1)" "unprognostic (8.72e-2)" "unprognostic (8.13e-4)" "unprognostic (3.93e-3)" "unprognostic (7.05e-2)" "unprognostic (3.29e-3)" "unprognostic (5.64e-2)" "unprognostic (3.34e-4)" "unprognostic (1.72e-1)" "unprognostic (1.13e-2)" "unprognostic (9.16e-4)" "unprognostic (4.01e-1)" "unprognostic (1.89e-4)" "unprognostic (2.01e-2)" "unprognostic (9.01e-2)" "unprognostic (8.23e-2)" "unprognostic (1.43e-2)" 1.9 8.4 34.3 0.6 40.6 0.4 1.8 0.0 49.7 1.0 0.0 1.4 0.8 1.5 0.7 0.7 1.2 0.5 1.4 54.2 2.4 1.4 0.1 1.0 0.3 0.0 4.7 1.0 1.1 4.4 28.0 0.1 0.5 0.8 0.8 10.0 0.7 0.5 14.1 1.5 1.3 1.4 0.9 0.5 0.7 2.2 0.9 0.2 4.1 3.3 0.2 0.8 1.0 15.3 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.9 0.1 1.8 0.0 0.6 0.0 0.0 0.1 0.3 0.0 0.2 0.2 0.1 0.0 0.1 0.0 5.8 0.1 0.1 0.0 0.1 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 2.0 0.0 0.0 0.1 5.5 4.5 0.4 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.4 0.1 0.0 0.1 0.0 0.0 34.3 40.6 0.0 49.7 54.2 2.4 0.0 4.7 0.5 0.9 0.9 15.3 7.7 0.0 0.5 3.9 0.0 5.7 1.1 0.0 1.2 31.6 1.3 1.0 2.1 0.0 0.0 1.8 6.2 0.1 0.0 0.3 0.0 0.3 13.9 0.2 0.3 13.0 4.2 0.0 58.8 1.0 0.1 1.5 0.0 0.2 0.0 1.4 5.3 0.0 0.2 20.2 35.7 0.0 0.0 0.0 2.3 31.3 0.0 0.4 0.0 5.6 0.0 6.3 1.0 4.5 2.5 0.3 0.0 0.4 0.0 1.0 0.1 0.5 0.0 6.0 6.6 5.7 0.8 1.0 2.0 0.4 5.5 0.0 0.1 1.4 0.1 0.5 SH3RF1 "KIAA1494, POSH, RNF142, SH3MD2" ENSG00000154447 "SH3 domain containing ring finger 1" Q7Z6J0 4 169094259-169270956 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 146.3;Oligodendrocytes: 213.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 4.2;myeloid DC: 2.5;non-classical monocyte: 6.7" "Group enriched" "Detected in many" 15 "dendritic cells: 2.5;monocytes: 6.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074783 Approved Supported "Vesicles,Intermediate filaments" No No "Cluster 51: Monocytes - Innate immune response" "Cluster 45: Intestine - Brush border" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "Intermediate filaments" "HPA074783: AB_2732268" "unprognostic (4.14e-1)" "unprognostic (4.67e-2)" "unprognostic (1.23e-1)" "unprognostic (7.83e-2)" "unprognostic (1.02e-1)" "unprognostic (1.30e-2)" "unprognostic (1.29e-1)" "unprognostic (2.65e-1)" "unprognostic (8.44e-2)" "unprognostic (9.58e-2)" "unprognostic (4.77e-3)" "unprognostic (7.88e-2)" "prognostic favorable (5.51e-8)" "unprognostic (4.43e-2)" "unprognostic (1.63e-1)" "unprognostic (5.99e-2)" "unprognostic (1.77e-1)" 9.8 3.7 8.7 4.4 10.0 3.4 8.2 7.6 13.1 5.7 5.9 15.1 13.8 4.3 5.7 5.9 5.6 11.9 5.7 18.2 8.6 12.2 8.0 9.4 3.3 8.8 9.7 8.5 10.4 3.7 3.7 7.4 9.4 14.3 13.6 2.4 15.8 8.4 9.4 5.1 13.1 4.0 8.2 3.9 24.7 6.1 9.5 2.0 19.9 10.0 3.2 9.3 4.4 13.0 15.2 12.2 11.0 31.9 11.5 14.3 14.1 40.5 19.7 30.0 13.8 12.5 17.8 0.0 1.9 43.1 8.1 9.8 8.9 16.2 32.4 0.1 5.2 8.7 27.4 6.5 26.0 3.1 0.3 8.5 8.6 25.7 19.9 37.3 18.7 3.3 0.1 0.0 27.8 6.0 3.1 2.9 5.6 19.2 10.5 4.5 3.6 0.6 13.6 11.8 8.3 9.9 10.4 15.7 4.2 4.7 5.2 1.3 17.1 14.2 11.0 23.6 14.7 1.1 0.0 0.1 16.0 3.0 17.3 0.0 1.0 0.0 0.0 4.2 0.0 0.3 0.0 0.0 2.5 0.1 0.0 0.0 0.0 0.2 6.7 0.2 0.0 0.6 8.7 10.0 7.6 13.1 18.2 8.6 8.8 9.7 9.4 8.2 9.5 13.0 28.0 64.1 37.7 146.3 3.4 34.3 48.3 11.9 13.6 3.5 21.1 15.6 11.2 44.3 34.4 27.6 0.0 12.7 0.4 69.3 11.7 42.2 5.5 28.5 14.2 13.0 31.3 2.1 54.9 63.7 22.1 16.5 65.7 46.5 10.2 5.6 11.4 12.4 7.4 0.0 54.9 27.1 12.2 9.3 5.3 3.5 12.2 11.1 3.6 52.5 3.9 11.3 0.0 89.5 213.0 68.4 37.2 12.0 2.4 63.2 28.9 18.4 31.7 1.2 65.7 24.1 36.9 5.4 10.7 9.4 12.6 13.1 1.7 6.5 34.4 72.0 SIK2 "DKFZp434K1115, KIAA0781, LOH11CR1I, QIK, SNF1LK2" ENSG00000170145 "Salt inducible kinase 2" Q9H0K1 11 111602449-111730855 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 113.3;Excitatory neurons: 217.6;Inhibitory neurons: 132.4;Oligodendrocytes: 191.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "ASC diff: 50.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016026, HPA071049" Approved Approved "Nucleoplasm,Nuclear speckles,Vesicles,Intermediate filaments,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Vesicles" "Nuclear speckles, Intermediate filaments, Cytosol" "HPA016026: AB_1857321, HPA071049: " "unprognostic (2.35e-1)" "unprognostic (1.10e-1)" "unprognostic (1.08e-1)" "unprognostic (1.10e-2)" "unprognostic (1.59e-2)" "unprognostic (4.81e-2)" "prognostic favorable (4.93e-4)" "unprognostic (6.41e-2)" "unprognostic (1.87e-1)" "unprognostic (1.40e-2)" "unprognostic (3.72e-3)" "unprognostic (9.27e-2)" "prognostic favorable (1.17e-9)" "unprognostic (1.23e-1)" "unprognostic (2.79e-1)" "unprognostic (2.82e-3)" "unprognostic (2.13e-2)" 29.7 9.3 9.2 5.3 12.4 3.1 20.7 7.9 11.1 7.6 11.0 7.9 5.9 7.3 5.0 5.9 8.1 10.0 12.3 9.5 14.7 11.4 22.7 11.7 4.4 11.9 11.9 14.9 31.8 21.3 16.6 5.8 10.6 6.7 6.2 30.7 13.8 6.2 33.1 8.9 7.5 5.9 5.5 4.6 17.6 3.0 9.3 5.4 8.7 23.2 4.3 7.7 6.1 11.6 9.2 6.0 10.3 11.1 50.3 14.8 6.1 7.9 11.2 5.9 6.7 20.5 9.6 7.2 10.7 9.2 6.9 12.7 8.2 5.9 7.6 5.4 3.4 7.9 5.2 10.1 10.9 7.7 4.9 14.5 8.6 8.7 11.1 11.7 7.1 7.1 7.4 10.3 9.4 4.3 8.0 7.0 3.5 7.6 5.9 10.6 11.0 8.7 13.1 8.2 4.8 11.3 11.6 4.7 4.5 9.4 11.5 6.2 9.9 12.9 7.7 8.3 10.9 2.9 2.4 14.8 4.2 10.6 8.8 0.3 0.7 0.6 0.7 0.7 0.3 0.4 0.5 0.5 0.6 0.4 0.2 0.4 0.3 0.5 0.6 0.3 0.5 0.5 9.2 12.4 7.9 11.1 9.5 14.7 11.9 11.9 10.6 5.5 9.3 11.6 22.1 19.2 24.8 113.3 14.1 14.7 6.2 5.2 18.2 15.7 10.5 9.9 21.3 27.1 10.0 16.5 66.7 4.4 11.4 15.6 5.9 10.4 16.5 27.7 14.9 18.8 18.0 12.4 217.6 7.9 4.6 20.1 27.5 45.3 9.5 24.3 9.3 38.7 5.4 32.0 132.4 11.3 4.1 12.4 16.9 14.1 11.5 13.3 19.6 73.1 6.0 14.5 4.1 86.0 191.9 8.4 10.3 14.7 8.9 6.9 8.3 23.1 13.4 60.9 0.0 19.1 19.0 3.9 6.4 10.3 11.9 5.2 12.6 5.0 11.5 7.1 SLC16A8 "MCT3, REMP" ENSG00000100156 "Solute carrier family 16 member 8" O95907 22 38078134-38084093 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 9.1" "Cell type enhanced" "Detected in some" "Leydig cells: 4.4;Melanocytes: 5.4;Oligodendrocytes: 4.0;Spermatogonia: 7.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.0;SiHa: 2.1;T-47d: 1.3;U-2 OS: 1.2;U-266/70: 4.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA075017 Approved Approved "Intermediate filaments,Focal adhesion sites" No NA "Cluster 65: Brain - Ion transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Focal adhesion sites" "Intermediate filaments" "HPA075017: AB_2732276" "unprognostic (1.22e-2)" "unprognostic (2.25e-2)" "unprognostic (5.07e-6)" "unprognostic (2.99e-2)" "unprognostic (1.37e-1)" "unprognostic (1.84e-2)" "unprognostic (2.99e-2)" "unprognostic (1.74e-1)" "unprognostic (1.24e-1)" "unprognostic (1.76e-1)" "unprognostic (1.63e-2)" "unprognostic (1.32e-2)" "unprognostic (2.34e-4)" "unprognostic (7.69e-2)" "unprognostic (1.15e-1)" "unprognostic (4.06e-1)" "unprognostic (9.71e-5)" 0.5 0.3 1.1 0.0 3.3 0.2 0.6 0.2 6.0 0.7 0.0 0.3 0.1 0.4 0.0 0.3 0.9 0.1 0.6 0.8 1.1 0.4 0.2 0.3 0.0 4.0 1.4 0.3 0.4 0.0 1.6 0.0 3.6 1.7 0.0 0.1 1.2 0.0 0.5 0.7 0.2 0.0 0.3 0.3 0.4 0.8 2.8 0.0 0.7 0.0 0.0 0.4 0.7 9.1 0.3 0.0 0.1 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.1 0.7 0.1 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.6 0.4 0.1 2.1 0.0 0.2 0.1 1.3 0.0 0.0 0.0 1.2 0.0 0.0 4.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 3.3 0.2 6.0 0.8 1.1 4.0 1.4 3.6 0.3 2.8 9.1 0.6 0.0 0.0 0.7 0.0 1.3 0.5 0.6 0.6 0.1 0.6 0.8 0.7 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.1 1.3 0.1 0.9 0.2 0.0 0.0 0.4 0.0 0.0 2.2 0.0 0.4 0.0 1.7 0.7 0.1 1.0 0.0 0.4 0.2 0.0 0.8 1.4 2.5 4.4 0.7 5.4 0.0 0.0 1.4 0.0 0.5 4.0 0.3 0.0 2.2 0.0 0.3 0.0 0.0 0.0 0.7 0.0 1.5 2.4 2.1 7.7 0.5 0.9 0.0 0.3 0.6 0.1 0.7 SLC1A6 EAAT4 ENSG00000105143 "Solute carrier family 1 member 6" P48664 19 14950034-15022990 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 88.2;testis: 28.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 17.1;Early spermatids: 35.3;Horizontal cells: 23.5;Late spermatids: 31.8;Syncytiotrophoblasts: 40.0" "Cancer enriched" "Detected in some" 7 "urothelial cancer: 5.2" "Region enriched" "Detected in all" 6 "cerebellum: 88.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 7.4;NTERA-2: 6.1;U-698: 28.3" "Region enriched" "Detected in all" 6 "cerebellum: 136.3" "Region enhanced" "Detected in all" "cerebellum: 53.8" "HPA041505, HPA044066" Enhanced Supported Supported "Plasma membrane,Intermediate filaments" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "Intermediate filaments" "HPA041505: AB_2677520, HPA044066: AB_2678796" "unprognostic (3.62e-2)" "unprognostic (1.35e-1)" "unprognostic (4.41e-2)" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "unprognostic (5.94e-3)" "unprognostic (8.90e-2)" "unprognostic (6.52e-4)" "unprognostic (1.55e-1)" "unprognostic (5.40e-3)" "unprognostic (1.11e-2)" "unprognostic (9.92e-2)" "unprognostic (1.35e-1)" "unprognostic (5.57e-2)" "prognostic unfavorable (6.88e-6)" 0.1 0.2 9.1 0.2 10.8 0.9 0.4 88.2 14.4 0.1 0.5 0.2 0.3 0.4 1.7 0.1 0.2 0.2 0.2 14.5 5.0 0.1 0.2 0.2 0.3 3.7 7.5 0.3 0.6 0.9 0.3 0.7 8.1 0.5 0.3 2.3 0.4 0.5 0.3 8.6 0.3 0.2 3.2 0.4 0.2 28.0 6.6 0.2 0.3 0.1 0.3 0.1 0.1 5.1 0.1 0.1 0.3 0.4 0.2 0.2 0.9 0.1 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.2 0.1 1.4 7.4 0.2 0.1 0.2 0.1 0.2 0.4 0.3 0.0 0.2 0.1 0.1 0.2 0.1 0.1 0.2 0.1 0.2 0.1 0.6 0.1 0.6 0.0 0.5 6.1 0.0 0.1 0.1 0.1 0.1 0.1 0.3 0.5 0.2 0.2 2.8 0.0 1.1 0.3 0.1 0.0 0.3 1.1 0.3 0.1 0.5 0.1 28.3 0.1 0.3 0.1 0.3 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.3 0.0 0.0 0.1 0.0 0.0 9.1 10.8 88.2 14.4 14.5 5.0 3.7 7.5 8.1 3.2 6.6 5.1 0.0 0.0 0.0 0.7 0.0 3.2 0.7 0.0 0.0 17.1 0.0 0.1 2.1 0.0 0.0 1.8 0.0 1.9 0.0 0.0 0.0 0.0 35.3 0.0 0.1 0.1 0.0 0.0 8.2 0.4 9.9 0.4 0.0 0.0 0.0 5.8 0.0 0.0 0.5 23.5 8.6 0.0 0.0 0.0 0.7 31.8 0.6 0.0 0.0 1.0 0.0 0.7 0.0 4.5 0.9 0.0 0.0 0.7 0.0 0.2 0.0 0.2 0.0 0.8 0.0 0.0 0.4 2.2 6.3 0.0 6.8 40.0 0.0 0.0 0.0 0.1 SPINT2 "HAI-2, Kop" ENSG00000167642 "Serine peptidase inhibitor, Kunitz type 2" O43291 19 38244035-38292615 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 1371.3;Syncytiotrophoblasts: 1413.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 852.5;CAPAN-2: 1219.1;OE19: 1500.4;RPTEC TERT1: 896.7;SK-BR-3: 789.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011101, CAB018969" Approved Uncertain "Plasma membrane,Intermediate filaments,Cytosol" No NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane, Intermediate filaments, Cytosol" "CAB018969: , HPA011101: AB_1079039" "unprognostic (5.13e-2)" "unprognostic (1.06e-3)" "unprognostic (1.40e-1)" "unprognostic (6.25e-2)" "unprognostic (1.13e-1)" "unprognostic (1.91e-2)" "unprognostic (2.23e-1)" "unprognostic (2.03e-2)" "unprognostic (3.51e-1)" "unprognostic (1.67e-2)" "unprognostic (2.89e-2)" "unprognostic (2.04e-1)" "prognostic favorable (3.41e-4)" "unprognostic (3.59e-1)" "unprognostic (1.32e-1)" "unprognostic (6.94e-2)" "unprognostic (2.68e-2)" 10.5 44.6 56.9 65.3 57.3 81.1 178.5 47.2 66.3 145.6 80.0 297.0 247.4 44.6 269.6 351.9 189.7 105.1 13.6 58.9 92.9 216.1 14.3 138.3 37.4 52.0 54.8 83.3 234.2 252.9 435.9 156.4 56.2 181.8 251.7 23.6 503.9 111.3 1.8 257.0 267.0 19.0 47.6 50.2 219.4 215.7 70.3 82.6 321.3 0.9 101.3 140.1 157.6 51.0 852.5 603.0 3.0 3.4 0.4 0.0 387.4 16.2 1.7 1.2 2.6 426.8 1219.1 6.7 65.8 4.6 1.2 274.6 42.7 587.0 1.4 7.9 51.7 159.4 15.3 0.9 0.9 1.5 0.8 0.1 662.5 0.7 278.6 71.5 2.0 144.2 4.0 0.4 1.0 652.8 25.6 2.8 60.4 1500.4 172.1 87.9 0.6 386.2 896.7 707.4 222.2 3.4 246.5 789.2 2.1 231.0 353.7 104.5 0.7 1.2 4.7 3.4 3.2 56.1 76.4 47.6 1.0 11.2 1.0 515.9 127.4 531.9 3.8 91.1 7.9 143.2 44.2 21.5 297.7 160.4 86.1 80.4 56.4 19.0 64.4 523.5 19.1 142.8 56.9 57.3 47.2 66.3 58.9 92.9 52.0 54.8 56.2 47.6 70.3 51.0 8.0 368.6 233.9 10.4 90.9 376.9 563.9 954.0 278.9 14.3 487.2 518.2 2.8 316.0 655.6 559.1 6.2 1371.3 79.5 1028.3 101.8 866.9 61.8 401.4 47.3 24.3 360.5 83.9 20.7 659.8 502.0 34.6 234.5 490.4 115.5 371.8 32.5 2.0 230.3 3.3 39.8 672.8 734.5 55.5 139.0 55.6 19.0 133.6 88.9 24.4 364.3 129.6 1.0 4.5 9.0 910.4 889.4 17.0 61.3 684.9 918.6 208.8 495.1 17.2 52.6 1.2 76.7 545.2 264.1 507.7 428.3 1413.2 42.6 3.4 582.2 989.6 SRMS "C20orf148, dJ697K14.1, PTK70, SRM" ENSG00000125508 "Src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites" Q9H3Y6 20 63540810-63547504 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "stomach 1: 1.6" "Cell type enriched" "Detected in single" 4 "Gastric mucus-secreting cells: 3.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 3.3;MCF7: 3.0;OE19: 4.4;RT4: 6.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB044668, CAB044669, HPA073987" Uncertain Approved "Intermediate filaments,Actin filaments,Cytosol" No NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 43: Cardiomyocytes - Nuclear processes" "Intermediate filaments" "Actin filaments, Cytosol" "CAB044668: AB_10609403, CAB044669: AB_10608235, HPA073987: AB_2686650" "unprognostic (2.26e-2)" "unprognostic (1.26e-2)" "unprognostic (2.52e-3)" "unprognostic (8.32e-2)" "unprognostic (2.62e-1)" "unprognostic (5.47e-3)" "unprognostic (1.65e-1)" "unprognostic (2.28e-1)" "unprognostic (9.63e-2)" "unprognostic (6.48e-3)" "unprognostic (7.28e-3)" "unprognostic (1.46e-1)" "unprognostic (1.73e-3)" "unprognostic (2.58e-3)" "unprognostic (4.75e-2)" "unprognostic (4.97e-2)" "unprognostic (2.54e-3)" 0.0 0.0 0.1 0.2 0.1 0.1 0.4 0.6 0.2 0.0 0.0 0.7 0.2 0.0 0.7 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.8 0.0 0.0 0.4 0.2 0.0 0.1 0.9 1.6 0.2 0.1 0.0 0.1 0.0 0.1 0.3 0.0 0.6 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.3 0.1 1.3 0.0 0.0 1.5 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.0 0.0 0.1 0.0 4.4 0.4 0.0 0.1 0.0 0.0 6.0 0.4 0.5 0.1 1.2 0.2 0.0 1.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 STK3 "KRS1, MST2" ENSG00000104375 "Serine/threonine kinase 3" Q13188 8 98371228-98942827 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglial cells: 152.7;Oligodendrocytes: 189.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "dendritic cells: 7.9;granulocytes: 8.8;monocytes: 8.5" "Cell line enhanced" "Detected in many" "A-431: 85.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007120, CAB025316" Uncertain Approved "Intermediate filaments,Rods & Rings" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 64: Astrocytes - Nervous system maintenance" "Intermediate filaments, Rods & Rings" "CAB025316: , HPA007120: AB_10601664" "unprognostic (7.88e-3)" "unprognostic (1.96e-1)" "unprognostic (6.57e-2)" "prognostic unfavorable (1.53e-4)" "unprognostic (2.95e-1)" "unprognostic (1.12e-3)" "unprognostic (9.68e-3)" "prognostic unfavorable (4.25e-4)" "unprognostic (6.71e-2)" "unprognostic (9.83e-2)" "prognostic unfavorable (9.21e-5)" "unprognostic (9.16e-2)" "unprognostic (1.03e-1)" "unprognostic (2.27e-1)" "unprognostic (1.29e-1)" "unprognostic (5.86e-2)" "unprognostic (9.72e-2)" 15.1 14.4 5.6 7.9 7.0 3.5 14.1 6.6 7.4 17.4 7.2 13.1 5.5 24.9 14.3 10.2 17.0 14.2 9.1 5.1 6.3 15.6 14.3 11.1 5.5 7.7 6.7 25.0 10.0 16.1 6.4 18.5 7.4 16.5 6.7 12.0 10.7 17.6 11.4 9.6 8.3 17.2 6.3 6.8 8.5 11.4 7.1 5.1 11.9 8.6 5.5 13.6 13.7 7.9 85.3 15.7 16.2 22.0 51.2 25.4 16.4 28.8 25.6 26.3 22.8 11.7 35.7 0.0 25.6 28.7 14.1 33.4 11.4 24.8 42.2 20.5 14.8 22.9 7.2 8.0 17.5 7.7 19.0 17.0 41.9 13.5 36.6 17.2 11.5 13.4 9.8 12.2 19.4 10.7 19.3 9.4 4.9 58.0 6.1 17.1 14.1 7.5 29.9 10.7 4.3 9.6 18.4 21.1 18.2 21.0 17.8 12.3 8.7 17.9 11.5 27.1 16.3 9.8 15.5 6.2 15.9 9.5 29.0 2.0 8.3 4.6 1.3 8.5 1.4 1.8 0.7 1.8 7.9 1.1 1.0 0.6 8.8 2.0 5.4 3.3 0.1 2.8 5.6 7.0 6.6 7.4 5.1 6.3 7.7 6.7 7.4 6.3 7.1 7.9 25.9 38.5 37.4 132.9 6.0 43.7 44.8 25.3 23.3 6.9 29.0 15.5 16.6 31.5 37.7 29.5 14.6 43.6 2.5 11.7 23.5 21.5 118.3 23.7 65.8 31.3 9.1 16.2 34.3 18.9 56.1 39.8 9.7 28.9 17.1 13.3 24.3 23.7 19.2 10.1 33.5 7.8 26.4 17.0 25.1 77.1 91.0 18.6 24.9 152.7 13.8 15.0 3.1 60.3 189.9 24.9 13.1 74.1 6.2 42.1 32.3 25.0 29.0 15.6 39.5 43.8 39.7 16.7 12.6 12.3 40.5 64.7 5.9 47.0 13.8 36.0 SYCE1L MRP2 ENSG00000205078 "Synaptonemal complex central element protein 1 like" A8MT33 16 77199408-77213215 "Predicted intracellular proteins" Meiosis "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 23.5" "Cell type enhanced" "Detected in many" "Breast glandular cells: 89.5;Breast myoepithelial cells: 125.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 11.1;U-698: 8.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA062464, HPA066691" Enhanced "Intermediate filaments" No No "Cluster 35: T-regs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 35: Glandular cells - Unknown function" "Intermediate filaments" "HPA062464: , HPA066691: AB_2685702" "unprognostic (5.54e-3)" "unprognostic (2.15e-1)" "unprognostic (1.65e-1)" "prognostic favorable (6.65e-4)" "unprognostic (1.32e-1)" "unprognostic (2.32e-1)" "unprognostic (3.48e-2)" "unprognostic (2.00e-3)" "unprognostic (6.28e-3)" "unprognostic (1.02e-1)" "unprognostic (7.48e-2)" "unprognostic (5.13e-2)" "prognostic unfavorable (2.11e-5)" "unprognostic (9.27e-2)" "unprognostic (4.27e-1)" "unprognostic (2.68e-2)" "unprognostic (1.73e-2)" 2.7 1.5 1.7 0.4 1.3 1.2 3.6 7.9 2.3 5.5 1.6 1.7 0.8 3.0 1.5 1.5 3.2 0.4 1.4 1.2 3.0 3.2 1.4 1.4 1.0 2.0 2.7 5.2 2.0 0.7 2.1 0.5 1.7 7.0 0.5 2.8 5.1 0.6 0.8 2.9 2.1 0.5 2.0 2.0 1.1 23.5 1.6 0.4 3.4 0.0 0.6 2.4 4.1 1.1 2.4 0.9 2.3 0.9 0.2 0.0 0.3 0.6 0.2 0.3 0.6 0.4 4.6 1.3 2.6 0.4 0.1 3.4 0.2 0.0 0.2 1.4 11.1 0.3 0.8 0.0 1.5 0.8 0.8 0.0 0.3 0.1 0.2 0.3 1.6 2.0 0.6 0.1 0.2 3.6 0.5 0.9 1.4 0.3 3.8 5.7 0.6 0.4 2.3 0.5 2.3 2.2 0.3 0.2 0.0 0.1 0.0 0.8 5.1 0.3 5.1 0.6 0.1 4.1 1.9 8.0 1.9 0.4 0.1 4.5 1.3 13.9 6.8 2.6 7.8 4.0 8.2 9.0 1.8 2.6 8.9 8.4 1.4 3.6 2.1 13.8 12.6 3.4 1.7 1.3 7.9 2.3 1.2 3.0 2.0 2.7 1.7 2.0 1.6 1.1 19.5 3.2 3.7 6.5 7.6 17.3 10.9 15.2 15.9 3.7 89.5 125.7 1.7 32.9 7.4 27.6 10.4 6.8 8.9 22.4 15.6 24.8 24.7 7.1 4.5 15.9 22.4 1.3 5.9 27.9 4.0 13.8 2.6 15.2 1.3 5.0 18.2 13.2 2.3 1.7 9.2 52.0 12.2 15.8 9.7 55.5 13.7 3.6 19.6 5.6 2.9 35.1 3.1 7.5 10.6 13.9 27.2 6.8 6.9 16.7 22.3 31.9 2.6 44.5 6.6 19.9 5.4 30.4 9.9 6.7 17.0 2.9 9.4 0.5 52.5 7.1 SYNE2 "DKFZP434H2235, KIAA1011, Nesp2, Nesprin-2, NUA, NUANCE, SYNE-2" ENSG00000054654 "Spectrin repeat containing nuclear envelope protein 2" Q8WXH0 14 63761899-64226433 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Actin-binding "Disease variant, Emery-Dreifuss muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 198.5" "Cell type enhanced" "Detected in all" "Granulosa cells: 454.6;Rod photoreceptor cells: 568.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 73.8" "Group enriched" "Detected in many" 11 "granulocytes: 73.8;T-cells: 38.5" "Cell line enhanced" "Detected in many" "Daudi: 48.8;SiHa: 29.8;U-698: 27.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003435, HPA050204" Enhanced Approved "Nuclear membrane,Intermediate filaments" No Yes "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" "Nuclear membrane, Intermediate filaments" "HPA003435: AB_1080162, HPA050204: AB_2681051" "unprognostic (1.93e-2)" "unprognostic (3.72e-2)" "unprognostic (1.91e-1)" "unprognostic (2.33e-1)" "unprognostic (2.64e-1)" "unprognostic (1.97e-3)" "unprognostic (9.04e-2)" "unprognostic (2.58e-3)" "unprognostic (1.99e-2)" "unprognostic (2.41e-2)" "unprognostic (1.25e-2)" "unprognostic (2.24e-1)" "prognostic favorable (3.56e-9)" "unprognostic (5.05e-3)" "unprognostic (3.14e-1)" "unprognostic (1.51e-2)" "unprognostic (4.80e-2)" 30.1 6.0 8.8 3.4 9.2 7.9 28.0 21.1 8.7 15.4 89.5 13.3 4.5 18.1 9.9 24.3 14.3 5.5 58.3 9.6 7.6 29.0 19.5 18.4 8.5 7.7 9.6 35.9 37.7 66.6 16.7 9.9 7.5 11.5 4.4 24.8 16.1 3.7 198.5 39.7 11.4 4.6 7.0 10.0 12.4 13.1 11.4 5.5 24.4 96.7 6.1 13.6 19.0 6.9 23.2 8.7 11.0 3.5 11.3 3.2 12.3 1.3 1.6 2.7 4.2 2.8 3.3 48.8 2.3 1.7 2.6 11.0 6.2 3.5 3.2 8.9 3.5 0.4 7.9 0.7 3.0 1.0 0.3 4.4 15.1 3.4 2.2 2.6 7.0 7.5 0.4 4.8 1.8 11.2 6.2 0.3 3.4 5.4 3.3 6.9 14.5 1.8 20.0 13.6 9.9 8.2 29.8 3.8 7.0 5.5 5.0 0.3 7.3 4.2 7.5 1.5 4.5 4.9 3.5 27.5 1.8 0.0 5.7 0.5 0.1 73.8 38.5 0.3 27.6 5.2 24.3 28.0 0.0 5.3 11.8 18.5 30.1 3.9 0.3 1.2 30.1 3.4 8.8 9.2 21.1 8.7 9.6 7.6 7.7 9.6 7.5 7.0 11.4 6.9 414.4 307.7 140.1 8.5 44.9 111.3 138.9 46.4 174.2 27.4 70.3 59.1 261.4 105.8 184.5 202.3 183.5 168.8 226.8 51.0 19.6 108.2 9.4 249.9 71.2 238.8 46.2 10.5 9.5 55.4 65.7 59.6 126.9 365.2 25.9 454.6 73.5 33.3 17.7 6.7 13.9 60.9 59.0 5.7 13.2 14.3 100.9 12.8 48.0 128.4 8.9 107.2 300.7 33.2 6.6 71.7 27.9 53.4 180.3 65.0 35.9 72.2 196.1 568.7 111.7 73.5 167.0 13.0 17.0 104.6 87.5 224.0 222.1 69.5 80.6 80.6 SYNM "DMN, KIAA0353, SYN" ENSG00000182253 Synemin O15061 15 99098217-99135593 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 594.1;skeletal muscle: 624.7;urinary bladder: 406.3" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 103.5;Cardiomyocytes: 502.5;Muller glia cells: 127.8;Smooth muscle cells: 98.5" "Cancer enhanced" "Detected in all" "prostate cancer: 28.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 36.8;HeLa: 58.0;WM-115: 124.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017192, HPA040066, HPA044200, HPA077856" Enhanced Supported "Intermediate filaments" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 17: WM-115 - Nervous system development" "Cluster 54: Cardiomyocytes - Muscle contraction" "Intermediate filaments" "CAB017192: , HPA040066: AB_2676830, HPA044200: AB_2678854, HPA077856: AB_2686861" "unprognostic (1.04e-2)" "unprognostic (1.37e-1)" "unprognostic (3.00e-2)" "unprognostic (6.10e-2)" "unprognostic (1.87e-1)" "unprognostic (1.15e-1)" "unprognostic (3.52e-2)" "unprognostic (1.10e-1)" "unprognostic (2.54e-1)" "unprognostic (1.00e-1)" "unprognostic (1.34e-2)" "unprognostic (6.75e-2)" "unprognostic (3.54e-3)" "unprognostic (2.80e-2)" "unprognostic (7.27e-2)" "unprognostic (5.92e-3)" "unprognostic (3.26e-3)" 37.2 20.3 51.4 26.5 66.0 0.4 56.7 70.1 58.2 11.8 52.5 594.1 27.1 50.8 12.7 169.6 36.5 19.2 144.2 44.4 75.4 6.9 4.8 23.1 4.2 81.7 66.6 14.1 6.3 8.2 23.2 14.0 81.6 150.6 52.0 40.3 25.6 291.3 624.7 17.0 105.7 160.9 71.6 2.9 158.4 5.2 69.3 3.7 11.2 277.1 4.0 406.3 41.0 79.8 6.6 36.8 8.1 21.9 15.9 0.9 0.5 3.7 5.3 2.1 1.3 5.4 4.9 0.0 5.3 5.3 17.7 4.2 5.5 0.1 1.6 0.5 9.0 0.1 58.0 5.4 9.0 0.0 1.0 0.9 0.3 3.7 0.8 6.0 4.3 0.0 0.2 7.4 5.5 3.7 0.7 0.8 7.2 0.7 11.4 0.0 7.5 5.5 2.1 3.6 3.6 4.2 21.9 3.4 13.5 12.7 0.2 3.6 4.8 4.1 0.4 2.9 8.9 0.1 1.0 0.0 0.4 0.0 124.5 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.3 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 51.4 66.0 70.1 58.2 44.4 75.4 81.7 66.6 81.6 71.6 69.3 79.8 14.8 0.0 1.7 15.3 0.9 2.3 0.7 0.9 2.8 12.6 32.7 103.5 502.5 0.0 1.2 0.0 16.7 1.5 6.6 2.1 0.0 0.5 9.5 1.3 1.0 24.2 3.0 0.0 15.6 1.3 0.7 20.3 5.1 4.2 0.0 1.1 3.6 1.3 0.3 42.1 9.8 0.9 0.0 0.0 5.1 4.5 1.2 2.0 5.4 12.2 0.6 127.8 1.0 2.5 14.0 0.2 2.3 4.1 5.4 2.0 0.6 0.3 3.1 10.2 32.9 19.6 98.5 7.9 11.5 2.1 3.7 0.4 5.9 0.2 0.7 0.9 TEKT4 MGC27019 ENSG00000163060 "Tektin 4" Q8WW24 2 94871430-94876823 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 13.4" "Group enriched" "Detected in many" 7 "Early spermatids: 137.1;Endometrial ciliated cells: 49.0;Late spermatids: 129.3;Respiratory ciliated cells: 51.6" "Cancer enriched" "Detected in single" 5 "endometrial cancer: 2.7" "Region enhanced" "Detected in single" "midbrain: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "midbrain: 2.9" "HPA048600, HPA053929, HPA069872" Enhanced Uncertain "Intermediate filaments" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 49: Ciliated cells - Cilium organization" "Intermediate filaments" "HPA048600: AB_2680460, HPA053929: AB_2682314, HPA069872: " "unprognostic (1.49e-2)" "unprognostic (4.00e-1)" "prognostic favorable (1.29e-4)" "unprognostic (9.95e-2)" "unprognostic (1.25e-1)" "unprognostic (2.35e-3)" "unprognostic (2.82e-3)" "unprognostic (2.15e-1)" "unprognostic (5.25e-2)" "unprognostic (5.00e-2)" "unprognostic (9.01e-2)" "unprognostic (5.25e-3)" "unprognostic (5.45e-3)" "unprognostic (2.33e-1)" "unprognostic (3.27e-2)" "unprognostic (7.56e-3)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.4 0.1 0.0 0.0 0.1 0.0 0.0 2.5 0.0 0.2 0.0 0.2 0.0 0.0 0.4 0.0 0.7 1.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 13.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.7 1.6 0.5 0.3 0.1 0.2 3.6 0.0 1.5 2.9 0.4 1.5 0.1 1.9 0.0 0.0 0.7 0.6 0.5 7.2 4.7 1.8 0.0 0.5 0.1 0.3 1.9 1.9 137.1 49.0 1.3 1.3 0.0 0.0 1.3 0.4 0.5 1.1 0.0 0.9 1.3 0.1 1.8 1.5 0.2 0.0 0.9 0.2 0.0 1.6 0.5 129.3 2.8 0.8 0.0 1.0 2.6 0.0 0.0 2.0 2.3 0.8 0.0 1.2 0.0 0.4 0.0 8.3 51.6 0.0 6.6 0.6 0.9 12.4 2.4 0.0 1.3 0.5 0.5 0.0 0.2 0.4 TNNI2 "AMCD2B, DA2B, FSSV" ENSG00000130598 "Troponin I2, fast skeletal type" P48788 11 1838981-1841680 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 25 "skeletal muscle: 7969.8;tongue: 2622.3" "Group enriched" "Detected in many" 6 "Extravillous trophoblasts: 449.4;Skeletal myocytes: 598.7" "Group enriched" "Detected in many" 10 "cervical cancer: 12.7;head and neck cancer: 33.6;pancreatic cancer: 12.9;urothelial cancer: 39.8" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 86.4" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 6 "CAPAN-2: 35.7;hTCEpi: 101.2" "Region enriched" "Detected in single" 6 "olfactory bulb: 5.1" "Not detected" "Not detected" "CAB018697, HPA055938" Enhanced Approved "Plasma membrane,Intermediate filaments" NA NA 110000 "Cluster 52: Eosinophils - Transcription" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane" "Intermediate filaments" "CAB018697: AB_628400, HPA055938: AB_2682976" "unprognostic (2.03e-2)" "unprognostic (1.13e-1)" "unprognostic (1.29e-2)" "unprognostic (3.70e-1)" "unprognostic (1.85e-1)" "unprognostic (1.02e-2)" "unprognostic (9.99e-3)" "unprognostic (1.01e-1)" "unprognostic (1.73e-1)" "unprognostic (1.51e-1)" "unprognostic (1.10e-1)" "unprognostic (2.70e-1)" "unprognostic (1.23e-3)" "unprognostic (5.92e-3)" "unprognostic (5.62e-2)" "unprognostic (1.77e-1)" "unprognostic (2.79e-2)" 3.0 1.8 0.3 1.1 0.3 6.1 7.9 0.3 0.6 1.0 0.4 1.2 0.3 0.8 0.3 66.9 0.9 5.6 1.7 0.3 0.4 0.7 1.6 7.8 1.6 0.4 0.4 0.7 8.8 0.0 0.9 3.0 0.4 14.0 0.2 0.0 216.1 3.2 7969.8 55.2 2.7 0.2 0.4 5.8 1.1 0.7 0.5 1.9 2.8 2622.3 1.0 27.4 3.2 0.6 0.0 0.0 0.1 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 2.4 35.7 1.0 0.2 0.0 0.0 1.7 0.0 1.3 0.0 0.0 0.0 0.1 0.0 2.1 0.2 0.0 0.1 8.1 101.2 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 3.1 0.0 0.1 1.2 2.4 0.0 1.0 0.0 1.0 0.0 0.7 0.0 0.0 12.3 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.0 13.8 5.8 53.3 0.1 12.5 0.1 3.8 0.0 0.0 8.0 4.8 0.0 0.0 39.7 0.4 17.6 86.4 0.0 2.5 0.3 0.3 0.3 0.6 0.3 0.4 0.4 0.4 0.4 0.4 0.5 0.6 1.2 3.2 4.4 0.0 9.1 25.1 2.6 1.8 15.4 0.0 0.5 23.7 5.6 21.5 3.0 0.0 0.0 33.8 15.7 0.1 0.0 1.4 0.0 1.4 0.2 2.0 0.0 0.0 0.0 0.6 449.4 2.4 1.1 0.1 10.8 0.4 0.4 0.3 39.6 0.0 0.0 0.0 2.0 18.8 10.7 0.0 0.3 25.9 0.0 0.0 16.0 0.0 1.0 0.0 0.0 1.4 0.0 0.0 4.2 0.1 0.0 0.2 13.2 0.0 0.0 598.7 2.4 0.0 0.6 2.7 6.5 87.2 1.9 4.3 0.0 0.9 TRIM32 "BBS11, HT2A, LGMD2H, TATIP" ENSG00000119401 "Tripartite motif containing 32" Q13049 9 116687305-116701300 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Limb-girdle muscular dystrophy, Mental retardation, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050060 Approved Approved "Intermediate filaments" No No "Cluster 35: T-regs - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Intermediate filaments" "HPA050060: AB_2681000" "unprognostic (2.47e-2)" "unprognostic (7.06e-3)" "unprognostic (5.50e-2)" "unprognostic (3.63e-1)" "unprognostic (5.08e-2)" "prognostic unfavorable (4.53e-4)" "prognostic unfavorable (4.72e-4)" "unprognostic (2.41e-3)" "unprognostic (2.92e-1)" "unprognostic (5.01e-2)" "unprognostic (1.79e-2)" "unprognostic (5.63e-2)" "unprognostic (6.03e-2)" "unprognostic (7.06e-2)" "unprognostic (2.73e-1)" "unprognostic (6.64e-3)" "unprognostic (9.77e-2)" 6.7 7.2 4.6 5.4 4.5 1.0 6.8 16.4 5.4 10.1 15.2 6.0 5.9 10.6 6.5 7.4 13.1 6.4 7.9 4.7 6.1 5.2 3.8 5.5 8.1 3.6 2.8 10.1 6.2 8.6 3.5 6.1 3.9 6.9 6.2 7.2 5.2 7.3 18.6 4.6 7.2 10.7 2.1 6.2 5.4 5.2 4.5 7.5 6.3 12.5 7.4 7.6 5.7 3.4 10.9 24.5 14.3 15.7 28.3 20.1 10.8 19.9 21.7 22.1 18.4 16.4 11.7 11.3 8.6 30.7 16.5 22.8 17.5 22.4 20.0 9.9 8.5 6.1 15.4 10.2 14.7 4.1 19.1 17.4 19.7 21.0 12.3 24.4 14.6 12.4 8.6 9.3 26.3 13.9 11.0 0.1 13.0 26.2 14.6 12.7 38.2 7.4 9.0 25.1 14.2 7.2 15.7 10.8 11.4 14.3 29.8 4.0 18.2 20.4 16.2 15.3 15.2 15.1 4.3 17.7 17.0 2.7 20.5 0.0 1.7 0.0 10.9 3.3 8.4 7.3 9.5 8.7 2.3 5.1 9.6 9.8 0.3 7.0 3.0 4.3 20.9 6.0 4.6 4.5 16.4 5.4 4.7 6.1 3.6 2.8 3.9 2.1 4.5 3.4 2.5 6.4 0.6 5.5 4.3 4.2 6.3 9.3 5.7 11.7 3.1 3.7 7.6 7.2 7.3 9.2 0.0 6.7 2.1 1.7 1.9 8.5 3.5 7.1 10.7 3.6 4.2 0.4 7.6 8.0 3.6 6.1 3.6 2.3 2.5 4.5 2.9 4.1 7.2 1.7 10.1 4.0 8.2 2.4 4.7 2.1 5.3 2.2 1.8 1.9 0.8 4.0 3.1 6.6 5.1 5.0 2.6 12.0 3.1 2.8 10.6 3.1 10.8 4.8 0.0 6.0 6.6 17.7 13.1 5.6 3.7 7.4 4.7 5.0 5.3 4.8 UAP1L1 ENSG00000197355 "UDP-N-acetylglucosamine pyrophosphorylase 1 like 1" Q3KQV9 9 137077517-137084539 "Metabolic proteins, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 21.7;Horizontal cells: 20.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HHSteC: 58.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044356 Approved Approved "Intermediate filaments,Cytosol" No No "Cluster 7: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 10: Non-specific - Unknown function" "Intermediate filaments" Cytosol "HPA044356: AB_10959902" "unprognostic (1.93e-1)" "unprognostic (1.11e-2)" "unprognostic (1.30e-1)" "unprognostic (1.25e-3)" "unprognostic (2.49e-2)" "unprognostic (3.80e-1)" "prognostic unfavorable (3.77e-4)" "unprognostic (3.01e-2)" "unprognostic (2.33e-1)" "unprognostic (5.65e-2)" "prognostic favorable (5.23e-4)" "unprognostic (1.22e-1)" "unprognostic (5.06e-2)" "unprognostic (1.67e-2)" "unprognostic (6.42e-2)" "unprognostic (3.28e-2)" "unprognostic (5.64e-3)" 11.6 14.1 13.5 5.5 18.7 3.1 9.5 14.3 16.4 15.0 15.8 8.1 5.7 6.7 5.1 6.0 7.6 5.3 11.0 14.4 14.0 14.0 2.8 12.5 7.9 16.6 15.8 3.8 9.6 7.9 15.4 6.3 15.8 13.0 3.6 2.9 11.0 5.6 2.7 10.1 10.8 3.5 12.6 22.0 10.2 3.2 19.0 2.4 14.1 2.7 5.9 10.0 9.1 24.1 0.8 5.8 0.0 15.7 26.4 12.1 4.5 8.1 21.1 22.4 15.4 11.7 2.6 3.7 4.7 8.3 40.6 12.1 29.6 2.0 4.6 10.0 2.7 7.9 9.5 11.3 58.5 0.1 31.5 8.9 2.1 12.7 10.4 10.4 17.7 7.3 2.4 18.0 15.2 13.5 0.8 8.1 2.6 28.3 8.3 12.8 0.2 11.3 8.9 1.1 9.3 5.8 2.0 44.3 18.7 3.7 23.9 21.8 14.1 40.2 8.6 28.3 3.9 19.6 30.1 7.9 34.9 8.6 11.7 0.1 1.0 0.0 0.2 0.5 0.8 0.5 0.1 0.3 0.5 0.2 0.2 0.3 0.1 0.0 0.0 0.3 0.5 0.4 13.5 18.7 14.3 16.4 14.4 14.0 16.6 15.8 15.8 12.6 19.0 24.1 2.4 0.0 8.4 16.0 6.9 6.1 0.6 2.0 4.0 6.8 4.8 3.9 4.0 5.7 1.5 0.0 2.1 0.4 7.1 2.1 11.7 1.4 0.2 2.2 4.9 3.1 1.8 0.4 3.3 0.9 5.0 4.0 1.1 3.4 4.5 0.8 7.1 0.7 21.7 20.2 5.1 1.8 6.1 10.9 9.9 0.2 2.5 11.2 8.8 6.5 9.1 4.7 3.1 6.6 18.4 0.8 1.9 3.8 5.6 2.0 0.5 3.4 1.1 5.1 0.0 3.0 16.5 0.6 1.5 3.5 4.4 1.4 4.5 1.0 3.1 0.2 UNC13B "hmunc13, Munc13-2, UNC13, Unc13h2" ENSG00000198722 "Unc-13 homolog B" O14795 9 35161992-35405338 "Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 57.7;Alveolar cells type 2: 80.7;Cone photoreceptor cells: 95.9;Excitatory neurons: 60.4;Microglial cells: 73.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024493, HPA062300" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles,Intermediate filaments" Yes No "Cluster 77: Retina - Visual perception" "Cluster 21: OE19 - Mitochondria" "Cluster 9: Photoreceptor cells - Phototransduction" Vesicles "Nucleoplasm, Golgi apparatus, Intermediate filaments" "HPA024493: AB_1858618, HPA062300: AB_2684742" "unprognostic (9.73e-3)" "unprognostic (2.33e-1)" "prognostic favorable (4.96e-4)" "unprognostic (6.56e-2)" "unprognostic (9.93e-2)" "prognostic favorable (8.51e-5)" "unprognostic (7.64e-2)" "prognostic favorable (6.59e-5)" "unprognostic (3.80e-1)" "unprognostic (1.64e-1)" "prognostic favorable (3.71e-4)" "unprognostic (1.74e-1)" "prognostic favorable (4.34e-11)" "unprognostic (2.40e-1)" "unprognostic (1.89e-1)" "unprognostic (1.48e-1)" "unprognostic (2.80e-2)" 12.6 12.8 10.5 5.6 13.3 1.0 10.3 6.6 14.5 12.5 15.7 22.2 11.6 10.1 7.7 17.5 10.4 11.5 13.6 11.4 7.2 21.8 12.8 38.9 1.8 8.3 9.5 7.3 21.3 15.0 11.5 6.0 7.8 22.6 25.0 41.2 17.8 23.3 24.2 12.3 13.4 11.9 7.3 4.7 17.9 15.6 10.6 3.0 12.2 10.4 5.0 10.2 12.7 9.0 9.8 12.8 13.9 22.6 26.3 14.6 11.8 15.7 7.1 11.4 15.3 10.7 4.5 0.0 7.0 20.6 20.1 4.7 35.4 18.2 14.5 0.0 11.3 5.9 36.6 13.9 12.7 2.2 6.4 11.6 14.0 18.0 18.5 18.2 37.3 15.8 13.5 8.1 13.5 7.5 2.1 0.2 12.6 30.2 13.3 0.1 8.6 3.4 15.5 12.6 14.9 15.7 11.0 6.8 11.4 23.0 11.6 7.5 34.5 7.8 7.2 12.3 12.2 12.7 16.2 0.0 8.5 18.4 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 13.3 6.6 14.5 11.4 7.2 8.3 9.5 7.8 7.3 10.6 9.0 6.7 57.7 80.7 28.7 0.8 3.1 1.1 2.1 3.4 42.3 7.3 4.4 11.4 18.6 16.7 9.2 95.9 3.7 0.1 24.4 3.9 6.0 6.9 8.2 5.1 8.5 24.6 1.7 60.4 12.2 2.1 4.8 16.3 13.9 2.5 8.7 5.7 12.5 4.9 6.7 17.7 31.9 0.0 2.4 3.0 12.3 2.1 3.7 7.2 73.1 0.1 5.7 0.0 42.3 36.7 7.8 11.9 3.0 4.2 11.7 10.5 7.8 10.0 40.8 6.6 8.4 6.5 8.7 7.5 14.3 7.4 2.9 1.0 5.7 19.5 5.7 VDR "NR1I1, PPP1R163" ENSG00000111424 "Vitamin D receptor" P11473 12 47841537-47943048 "Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors, Transporters" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "parathyroid gland: 235.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 141.7;Proximal enterocytes: 88.7;Undifferentiated cells: 72.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 7 "classical monocyte: 3.5;eosinophil: 1.9;intermediate monocyte: 6.5;myeloid DC: 5.1;neutrophil: 6.5;non-classical monocyte: 6.7" "Group enriched" "Detected in many" 8 "dendritic cells: 5.1;granulocytes: 6.5;monocytes: 6.7" "Cell line enhanced" "Detected in many" "HBEC3-KT: 55.5;HDLM-2: 80.0;U-937: 85.3" "Region enhanced" "Detected in single" "olfactory bulb: 2.1" "Region enhanced" "Detected in some" "spinal cord: 4.3" "CAB004617, HPA047740, HPA072102" Supported "Nucleoplasm,Intermediate filaments,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Intermediate filaments, Cytosol" "CAB004617: AB_628040, HPA047740: AB_2680142, HPA072102: " "unprognostic (1.11e-2)" "unprognostic (5.49e-2)" "unprognostic (1.01e-1)" "unprognostic (7.59e-3)" "unprognostic (3.33e-3)" "unprognostic (2.74e-2)" "unprognostic (4.78e-2)" "unprognostic (1.69e-1)" "unprognostic (1.40e-1)" "unprognostic (1.62e-1)" "unprognostic (5.53e-3)" "unprognostic (6.72e-2)" "prognostic favorable (4.89e-6)" "unprognostic (1.46e-1)" "unprognostic (8.76e-2)" "unprognostic (3.28e-1)" "unprognostic (3.82e-2)" 3.6 13.7 0.2 13.3 0.2 8.2 11.3 0.2 0.4 5.0 0.9 40.4 56.0 1.6 0.4 13.6 1.8 8.5 1.2 0.2 0.7 21.0 1.1 7.7 5.3 0.7 0.4 0.5 2.1 235.9 11.1 2.9 0.6 1.9 35.3 0.2 6.1 1.8 2.8 22.1 55.0 3.8 0.1 2.6 7.4 1.0 1.4 1.5 2.2 0.6 7.2 10.4 7.6 0.3 15.0 2.6 0.1 0.1 12.0 16.4 0.2 17.7 8.6 15.0 12.9 10.6 12.1 3.5 17.4 13.6 10.7 27.1 0.5 55.5 6.4 80.0 4.0 6.3 3.1 0.9 8.1 12.2 20.3 23.6 30.5 16.4 26.0 22.3 1.2 1.3 1.8 3.9 7.0 9.2 0.3 6.0 0.2 34.8 19.1 0.3 0.0 9.9 13.3 13.5 6.2 0.2 14.7 42.6 5.9 0.1 47.6 6.7 1.0 28.8 7.3 8.2 10.2 2.2 0.1 3.0 8.6 85.3 7.7 0.1 3.5 1.9 0.0 6.5 0.1 0.5 0.3 0.0 5.1 0.0 0.1 0.0 6.5 0.2 6.7 0.4 0.7 1.5 0.2 0.2 0.2 0.4 0.2 0.7 0.7 0.4 0.6 0.1 1.4 0.3 0.4 12.8 20.1 0.3 1.4 36.1 9.0 8.5 24.5 0.5 21.2 13.7 1.7 0.0 9.2 7.3 0.0 0.2 0.9 141.7 7.9 3.5 0.2 11.9 0.5 1.3 21.7 0.0 0.4 10.9 0.1 5.3 14.3 4.7 7.0 0.2 0.0 0.3 3.4 0.0 0.3 32.8 2.0 7.3 43.4 0.0 0.0 21.2 8.8 1.0 10.4 0.2 0.0 0.5 0.1 22.4 43.3 0.4 10.9 8.3 88.7 32.0 9.0 0.2 0.0 1.1 2.2 0.7 0.3 23.4 40.6 0.3 2.8 0.0 72.4 11.6 WDR37 KIAA0982 ENSG00000047056 "WD repeat domain 37" Q9Y2I8 10 1049538-1132384 "Disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 184.8;Late spermatids: 92.9;NK-cells: 86.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037376, HPA037565" Enhanced Approved "Intermediate filaments" No No "Cluster 48: NK-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 34: Spermatids - Unknown function" "Intermediate filaments" "HPA037376: AB_10672789, HPA037565: AB_10696937" "unprognostic (1.50e-2)" "unprognostic (2.07e-1)" "unprognostic (9.08e-3)" "unprognostic (8.51e-3)" "unprognostic (1.81e-1)" "prognostic favorable (1.75e-5)" "unprognostic (2.59e-3)" "unprognostic (3.56e-2)" "unprognostic (1.80e-1)" "unprognostic (1.62e-2)" "prognostic favorable (1.46e-6)" "unprognostic (3.16e-1)" "unprognostic (4.10e-2)" "unprognostic (1.30e-1)" "unprognostic (1.26e-1)" "prognostic unfavorable (1.34e-5)" "unprognostic (5.98e-2)" 8.4 16.5 10.4 9.3 10.5 22.2 7.8 0.4 18.7 8.1 2.0 8.9 7.3 7.9 8.9 9.1 7.8 6.1 17.6 13.1 2.5 8.7 10.3 10.3 12.5 1.5 1.9 9.7 10.1 9.8 14.6 6.3 2.9 8.1 6.7 14.9 7.6 5.1 18.3 11.5 11.2 6.6 0.0 21.0 10.3 21.2 3.1 10.3 9.5 15.7 9.8 7.0 7.9 9.7 12.4 9.0 11.6 9.4 10.9 15.8 8.2 15.5 8.4 9.5 9.4 11.3 10.4 6.1 9.2 20.3 2.0 11.2 6.1 18.1 8.1 7.4 10.0 14.8 9.6 7.7 7.7 8.8 16.0 19.8 13.6 13.6 4.8 11.3 21.0 12.1 9.1 7.3 15.2 10.9 9.8 6.9 6.4 9.6 4.8 14.9 6.5 10.5 13.2 13.8 5.2 10.1 7.2 13.3 11.9 8.8 12.8 17.9 27.7 7.5 2.5 24.8 12.5 13.4 13.3 8.2 17.4 9.9 5.4 6.0 4.8 3.5 10.0 6.2 8.7 5.5 5.6 7.4 5.2 4.4 6.3 7.3 3.8 11.2 7.1 4.8 5.3 5.2 10.4 10.5 0.4 18.7 13.1 2.5 1.5 1.9 2.9 0.0 3.1 9.7 10.5 3.2 8.1 33.6 14.5 13.4 13.0 7.5 10.2 16.3 8.4 7.2 23.3 5.7 7.9 11.0 12.5 6.2 27.4 8.6 0.0 4.8 184.8 5.7 8.6 13.6 10.7 6.5 65.3 6.1 4.2 9.0 13.3 11.1 12.0 7.3 30.7 7.0 9.0 8.4 59.7 8.1 8.2 18.8 13.7 92.9 12.5 14.8 16.0 43.1 23.7 5.3 86.5 36.7 47.3 9.5 8.3 18.0 9.6 13.6 7.2 4.8 4.9 14.7 6.6 13.0 8.5 11.6 14.3 11.9 12.4 11.4 19.1 10.1 5.9 19.7 ZDHHC12 "FLJ14524, ZNF400" ENSG00000160446 "Zinc finger DHHC-type palmitoyltransferase 12" Q96GR4 9 128720870-128724127 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 224.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA059339 Uncertain Approved "Nucleoplasm,Intermediate filaments" No No "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Intermediate filaments" "HPA059339: AB_2683985" "unprognostic (2.05e-1)" "unprognostic (5.81e-2)" "unprognostic (2.54e-1)" "unprognostic (1.53e-3)" "unprognostic (5.34e-3)" "unprognostic (3.11e-2)" "unprognostic (1.50e-3)" "unprognostic (6.56e-3)" "unprognostic (1.02e-1)" "unprognostic (6.42e-2)" "unprognostic (9.97e-2)" "unprognostic (9.41e-2)" "unprognostic (1.09e-2)" "unprognostic (8.82e-3)" "unprognostic (2.18e-1)" "unprognostic (1.95e-2)" "unprognostic (3.23e-1)" 18.8 23.9 7.8 15.5 7.7 41.3 19.3 7.5 9.9 16.8 8.4 40.5 26.3 12.9 7.1 67.8 12.0 14.1 13.7 7.4 8.8 30.6 52.3 23.3 20.0 9.6 7.8 7.4 67.1 9.8 11.3 16.3 8.4 26.6 13.7 0.5 43.2 12.5 15.6 42.4 36.8 6.3 8.4 31.7 49.2 24.7 10.5 12.4 16.2 4.1 13.7 18.7 30.5 9.7 53.5 127.6 6.0 31.3 17.6 12.1 59.4 32.8 28.8 34.5 22.9 109.6 61.5 37.3 29.6 25.5 62.9 139.8 13.0 65.0 3.8 65.0 31.7 20.1 92.7 49.1 34.7 33.1 87.1 19.9 44.7 29.6 11.0 17.7 25.6 65.6 18.8 93.6 7.1 187.3 45.9 66.2 26.8 118.8 107.6 21.0 21.0 108.4 28.7 43.4 42.1 30.4 46.2 64.1 18.3 9.6 98.9 35.6 27.5 0.1 36.9 25.9 45.8 58.1 106.8 17.3 61.3 38.4 41.4 231.1 122.3 385.6 105.1 123.9 91.2 94.6 95.9 101.5 100.1 111.0 99.2 91.4 269.5 90.5 150.0 244.7 130.9 101.0 7.8 7.7 7.5 9.9 7.4 8.8 9.6 7.8 8.4 8.4 10.5 9.7 10.0 16.0 12.0 1.3 31.8 16.2 43.3 94.0 10.8 1.2 55.5 30.4 14.8 77.2 59.0 46.0 0.0 183.9 39.1 171.0 13.7 106.8 73.2 20.7 11.5 21.1 51.2 51.1 0.6 200.0 224.0 14.2 38.7 52.5 18.4 13.7 35.7 55.3 137.0 0.0 0.5 108.5 67.1 62.2 20.9 30.0 9.6 46.5 42.7 6.5 115.3 18.4 81.4 0.5 2.0 133.8 167.7 7.2 43.3 56.5 186.0 48.5 20.1 2.0 6.6 5.4 16.3 36.0 18.6 55.2 28.1 134.1 34.1 22.0 110.0 77.5 ZKSCAN5 "ZFP95, ZNF914, ZSCAN37" ENSG00000196652 "Zinc finger with KRAB and SCAN domains 5" Q9Y2L8 7 99504662-99534700 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003201 Uncertain Approved "Intermediate filaments" No No "Cluster 22: NK-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Intermediate filaments" "HPA003201: AB_10610701" "unprognostic (2.47e-1)" "unprognostic (2.34e-2)" "unprognostic (2.99e-2)" "unprognostic (2.18e-1)" "unprognostic (4.42e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (7.59e-6)" "unprognostic (1.12e-1)" "unprognostic (2.15e-2)" "unprognostic (2.62e-1)" "unprognostic (5.35e-2)" "unprognostic (8.07e-2)" "unprognostic (1.18e-2)" "unprognostic (6.82e-2)" "unprognostic (1.66e-2)" "prognostic unfavorable (1.13e-4)" "unprognostic (3.42e-1)" 2.7 3.2 4.8 2.9 5.1 3.1 3.4 6.0 5.7 3.1 4.1 3.0 1.6 3.3 3.5 2.3 3.0 2.6 3.2 4.8 4.8 3.2 3.1 2.9 3.4 4.5 4.8 3.6 1.5 3.8 2.9 3.3 5.0 3.3 2.7 5.4 2.0 3.5 4.7 2.4 2.4 4.1 4.3 3.1 2.5 8.4 4.9 6.0 3.7 6.8 3.8 3.1 2.6 5.2 6.6 10.6 12.4 16.5 8.5 6.4 5.3 11.1 10.6 12.7 12.4 7.6 5.9 11.3 9.9 8.3 15.5 5.2 11.1 7.2 12.7 6.5 6.6 7.2 6.9 7.1 8.9 10.8 11.4 5.7 10.2 10.9 16.7 8.1 9.1 9.9 14.8 15.0 13.7 8.5 15.0 11.8 10.9 5.9 8.6 9.4 10.6 9.4 8.1 6.5 8.8 14.0 10.0 9.4 7.4 9.8 5.7 7.5 8.7 16.2 11.7 13.1 9.5 9.6 14.6 16.9 7.5 7.5 14.6 0.8 0.8 2.4 2.0 1.2 1.6 0.7 0.7 1.0 1.6 0.6 1.6 1.6 0.7 1.7 0.8 1.1 1.4 1.0 4.8 5.1 6.0 5.7 4.8 4.8 4.5 4.8 5.0 4.3 4.9 5.2 6.9 6.4 3.2 7.8 5.8 2.7 1.9 2.3 4.6 5.8 4.7 4.4 6.1 0.0 4.8 3.7 14.6 3.8 5.6 4.3 0.0 3.3 6.2 3.8 5.8 6.4 6.0 6.5 8.5 3.5 3.4 3.7 5.6 4.4 5.7 7.5 4.6 4.2 3.4 10.1 8.6 3.0 8.2 3.9 4.0 2.9 4.1 4.9 0.0 9.4 3.5 8.7 2.1 6.0 8.4 4.3 0.8 5.7 4.4 2.4 4.1 2.5 3.0 6.3 6.6 6.5 4.1 18.0 6.6 5.9 2.8 2.6 4.4 5.9 3.3 1.8 ZNF131 "pHZ-10, ZBTB35" ENSG00000172262 "Zinc finger protein 131" P52739 5 43065176-43192021 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007023, HPA027748, HPA074630" Approved Enhanced "Nucleoplasm,Intermediate filaments" No No "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 20: HeLa - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "Intermediate filaments" "HPA007023: AB_2667726, HPA027748: AB_2672374, HPA074630: AB_2686705" "unprognostic (1.23e-1)" "unprognostic (8.24e-2)" "unprognostic (4.70e-2)" "unprognostic (7.97e-2)" "unprognostic (8.84e-2)" "unprognostic (7.18e-2)" "prognostic unfavorable (1.56e-4)" "unprognostic (2.52e-1)" "unprognostic (2.98e-3)" "unprognostic (1.94e-2)" "unprognostic (5.83e-2)" "unprognostic (8.07e-2)" "unprognostic (2.09e-2)" "unprognostic (1.47e-2)" "unprognostic (2.76e-1)" "unprognostic (3.11e-3)" "unprognostic (1.46e-2)" 13.2 13.5 12.5 13.9 12.8 28.4 19.5 17.3 21.7 13.8 10.0 13.2 10.0 17.6 9.6 14.4 12.6 12.9 9.6 12.8 12.4 12.0 14.3 11.4 20.3 11.4 11.9 15.9 12.2 11.7 10.7 16.9 11.9 12.6 13.2 14.7 10.4 9.0 15.8 18.2 12.0 15.9 11.3 15.9 11.6 32.6 12.3 26.7 11.8 17.1 17.5 15.0 13.3 14.2 25.4 15.2 32.4 43.2 30.1 20.6 27.3 32.8 26.6 31.9 26.9 24.0 22.2 50.8 25.9 22.1 29.7 17.7 38.9 20.8 44.9 24.8 34.1 31.4 92.2 18.0 27.7 55.0 24.7 18.8 38.2 23.5 38.3 22.8 24.7 39.0 40.7 52.7 36.8 24.5 53.9 68.8 21.5 23.4 24.9 35.3 49.4 39.9 27.1 24.4 20.0 29.4 83.5 39.8 43.2 21.7 22.3 51.6 18.5 39.8 37.3 20.5 31.1 21.1 32.5 58.4 21.0 71.2 27.1 10.4 8.2 5.8 19.1 9.5 19.2 13.1 18.5 18.5 11.9 16.8 22.3 18.3 3.9 17.2 6.6 11.3 14.9 10.0 12.5 12.8 17.3 21.7 12.8 12.4 11.4 11.9 11.9 11.3 12.3 14.2 42.5 22.4 21.9 28.7 44.7 49.6 51.4 24.1 53.5 52.1 32.3 29.7 17.5 22.8 19.4 9.2 52.1 27.0 53.3 28.0 31.3 15.3 52.9 30.0 47.7 32.8 31.2 39.1 31.2 11.8 25.0 32.4 23.0 49.7 24.1 39.4 24.7 13.3 16.4 38.7 33.6 29.7 20.3 25.8 35.4 19.5 20.5 30.9 21.4 14.0 27.5 29.0 49.4 38.7 24.2 17.9 24.7 21.1 27.8 38.5 34.9 13.1 15.7 70.0 26.3 57.0 43.2 109.6 80.3 45.9 65.5 25.4 59.3 37.3 38.7 35.6 ZNF557 MGC4054 ENSG00000130544 "Zinc finger protein 557" Q8N988 19 7069703-7087968 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA003151, HPA029291" Uncertain Approved "Nucleoplasm,Intermediate filaments" No No "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Intermediate filaments" "HPA003151: AB_1859344, HPA029291: AB_10602357" "unprognostic (1.05e-1)" "unprognostic (2.96e-3)" "unprognostic (5.29e-2)" "prognostic favorable (5.70e-4)" "unprognostic (2.56e-2)" "prognostic favorable (3.67e-6)" "unprognostic (1.32e-1)" "prognostic favorable (2.62e-4)" "unprognostic (2.51e-2)" "unprognostic (2.51e-2)" "prognostic favorable (1.51e-4)" "unprognostic (2.28e-1)" "unprognostic (2.24e-2)" "unprognostic (1.52e-3)" "unprognostic (4.71e-2)" "unprognostic (6.18e-2)" "unprognostic (2.81e-3)" 1.5 1.9 1.2 1.8 1.5 3.9 1.9 3.1 1.7 1.6 1.5 1.5 1.1 1.7 1.6 1.7 1.9 1.3 1.2 1.3 1.0 1.8 2.2 1.4 2.6 1.4 1.1 2.4 1.8 1.7 1.5 1.5 1.5 1.5 1.4 1.9 1.4 1.4 1.4 2.0 1.7 1.6 0.9 2.3 1.8 2.1 1.4 2.4 2.1 1.0 2.5 1.6 1.5 3.1 2.1 2.2 2.3 5.0 3.1 2.1 1.9 2.1 2.2 2.3 2.8 2.8 1.3 4.4 3.6 2.3 1.8 2.9 4.0 2.3 2.3 4.0 2.6 5.6 4.7 1.5 2.1 6.0 5.9 3.0 2.3 2.4 3.7 2.3 2.0 3.8 2.2 6.7 3.1 3.0 5.0 2.1 2.2 2.0 3.0 3.6 3.6 2.4 1.7 4.9 2.7 3.2 3.1 2.4 2.3 2.0 1.9 3.1 3.9 2.2 1.7 5.0 2.3 6.8 5.8 3.9 2.4 3.1 2.0 5.6 3.1 3.8 4.6 2.9 4.7 4.1 5.0 4.0 3.1 5.4 5.8 4.9 3.5 5.9 2.7 5.7 4.3 1.7 1.2 1.5 3.1 1.7 1.3 1.0 1.4 1.1 1.5 0.9 1.4 3.1 5.5 3.2 4.4 5.2 8.3 1.5 6.9 2.7 2.2 9.4 6.1 5.8 5.4 7.2 6.1 7.3 0.0 5.9 5.8 5.4 15.6 6.2 0.9 3.4 8.9 6.9 5.4 6.1 9.2 6.2 4.2 5.6 4.6 4.6 8.2 9.4 8.6 3.8 6.1 16.8 8.9 5.8 2.0 9.8 2.9 0.5 4.4 6.0 0.0 5.6 9.0 6.1 14.4 3.5 8.8 6.1 6.2 5.7 5.9 6.8 6.1 8.1 4.3 6.8 0.0 7.8 6.7 23.2 19.9 3.6 1.3 5.7 7.7 6.7 5.5 6.9 ZNF573 FLJ30921 ENSG00000189144 "Zinc finger protein 573" Q86YE8 19 37735833-37817300 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 37.9;Inhibitory neurons: 28.1;Oligodendrocytes: 22.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA042776 Uncertain Approved "Intermediate filaments,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" "Intermediate filaments" Cytosol "HPA042776: AB_10961399" "unprognostic (3.79e-2)" "unprognostic (2.57e-1)" "unprognostic (1.29e-1)" "unprognostic (2.77e-2)" "unprognostic (3.72e-2)" "unprognostic (3.29e-2)" "unprognostic (8.26e-2)" "unprognostic (1.10e-1)" "unprognostic (3.62e-2)" "unprognostic (3.69e-1)" "unprognostic (1.03e-1)" "unprognostic (9.16e-2)" "unprognostic (9.97e-3)" "unprognostic (1.71e-1)" "unprognostic (2.17e-1)" "unprognostic (3.11e-2)" "unprognostic (2.60e-2)" 1.6 1.7 0.5 1.1 1.2 2.1 2.0 4.0 1.4 1.0 0.2 0.9 1.3 1.9 2.7 0.7 1.2 1.7 0.9 0.6 2.6 1.3 0.7 1.4 1.2 0.7 0.6 2.1 1.3 1.4 0.8 1.5 0.9 1.3 1.2 2.7 0.8 0.9 0.9 2.1 1.0 0.9 0.2 1.7 2.0 1.3 0.6 1.1 2.5 0.7 1.6 0.7 0.8 2.4 0.5 1.8 1.4 1.3 0.7 1.5 0.6 1.2 1.3 0.4 1.0 1.8 1.2 1.8 1.1 1.0 0.5 1.1 1.4 1.9 1.7 0.4 1.2 2.0 2.8 0.9 0.6 1.7 1.6 1.4 0.6 2.5 1.0 0.9 1.3 1.0 0.8 0.8 0.3 0.7 1.4 1.0 2.0 0.5 0.2 1.4 2.8 0.6 0.0 1.3 1.8 1.6 2.2 0.6 0.2 0.9 1.7 1.5 0.5 1.6 1.5 1.4 1.9 2.1 2.8 2.6 0.3 0.2 1.3 2.1 0.4 1.6 1.9 0.6 1.5 1.5 1.6 2.1 0.9 2.8 2.6 2.0 0.2 1.7 1.3 1.5 1.0 0.5 0.5 1.2 4.0 1.4 0.6 2.6 0.7 0.6 0.9 0.2 0.6 2.4 3.1 0.0 3.9 7.2 7.4 1.8 2.6 2.1 1.8 15.7 2.1 2.4 11.8 2.8 1.9 3.7 12.5 4.0 7.1 0.8 1.9 2.5 37.9 1.4 3.8 4.7 1.2 3.4 22.2 0.7 3.2 4.0 1.1 1.3 0.0 7.6 5.0 1.4 4.0 16.8 28.1 1.3 0.0 1.3 2.5 16.8 8.7 2.2 3.6 12.2 3.2 7.3 7.2 21.1 22.9 1.3 1.6 6.4 1.8 1.9 2.6 2.9 2.4 12.0 0.0 5.2 3.8 7.7 7.6 2.8 2.6 1.6 5.7 3.6 2.1 1.2 ZNF774 MGC75360 ENSG00000196391 "Zinc finger protein 774" Q6NX45 15 90352284-90369146 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 15.4;Granulosa cells: 45.3;Spermatocytes: 11.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HeLa: 9.0" "HPA030839, HPA030840" Uncertain Supported "Intermediate filaments,Cytosol" No No "Cluster 11: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" "Intermediate filaments" Cytosol "HPA030839: AB_2673630, HPA030840: AB_10602691" "unprognostic (1.11e-1)" "unprognostic (2.14e-1)" "unprognostic (1.38e-1)" "unprognostic (5.82e-3)" "unprognostic (3.29e-2)" "unprognostic (1.35e-1)" "unprognostic (6.89e-2)" "unprognostic (9.22e-3)" "unprognostic (7.82e-2)" "unprognostic (1.94e-1)" "unprognostic (3.43e-1)" "unprognostic (2.89e-2)" "unprognostic (2.71e-1)" "unprognostic (5.62e-2)" "unprognostic (1.27e-1)" "unprognostic (4.48e-2)" "unprognostic (4.82e-2)" 0.7 2.7 2.3 1.2 4.2 1.0 3.4 4.3 3.6 2.6 0.0 4.6 2.2 2.8 4.1 1.4 3.0 2.9 2.8 1.9 2.6 1.4 1.1 1.1 0.7 0.7 1.0 1.1 3.9 3.1 3.0 0.7 0.8 2.4 7.1 4.0 3.9 5.7 6.2 3.1 2.0 1.8 0.0 0.6 2.6 2.2 2.7 1.5 2.7 7.2 0.9 1.9 1.6 3.3 1.7 0.7 2.1 2.4 0.9 0.5 5.0 1.0 1.7 1.3 1.6 2.7 2.0 0.6 2.0 1.3 3.7 2.5 2.2 3.7 1.3 1.2 4.2 1.8 9.0 1.3 1.6 1.0 1.3 0.5 4.4 1.9 1.8 3.6 2.3 3.4 2.0 0.8 2.1 1.6 1.4 0.9 0.6 4.5 2.5 1.3 1.8 0.5 2.6 4.6 4.8 2.0 2.0 3.1 0.8 2.4 2.1 0.2 1.1 1.4 1.3 1.1 2.2 5.2 3.8 0.4 2.3 2.8 0.7 1.4 0.3 0.7 0.2 0.1 0.1 0.2 0.2 0.3 0.6 0.4 0.2 0.2 1.2 0.7 0.2 0.3 0.1 0.1 2.3 4.2 4.3 3.6 1.9 2.6 0.7 1.0 0.8 0.0 2.7 3.3 0.6 6.4 3.2 0.3 0.7 0.8 2.5 1.0 2.2 6.4 2.4 2.4 4.9 0.0 1.1 0.0 0.0 1.7 0.2 6.8 1.9 2.8 15.4 1.7 2.3 1.0 2.4 0.0 2.5 2.0 1.1 0.9 4.1 3.2 0.0 45.3 0.0 1.5 0.8 8.4 2.3 3.3 0.0 0.3 0.7 11.0 0.3 0.8 0.0 0.0 0.2 2.0 0.0 1.5 1.1 1.7 5.5 2.2 0.7 1.4 1.9 1.1 0.7 5.3 0.0 1.7 1.9 11.8 4.5 1.3 0.3 1.4 0.5 0.3 5.5 2.0 ZYG11B "FLJ13456, ZYG11" ENSG00000162378 "Zyg-11 family member B, cell cycle regulator" Q9C0D3 1 52726453-52827336 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 78.9;tongue: 62.0" "Cell type enhanced" "Detected in all" "Hepatocytes: 107.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028156 Uncertain Approved "Golgi apparatus,Intermediate filaments" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" "Golgi apparatus, Intermediate filaments" "HPA028156: AB_10602360" "unprognostic (2.54e-1)" "unprognostic (2.02e-1)" "prognostic favorable (5.42e-6)" "unprognostic (1.58e-2)" "unprognostic (4.44e-2)" "unprognostic (3.04e-3)" "unprognostic (7.15e-2)" "unprognostic (1.85e-1)" "unprognostic (4.84e-3)" "unprognostic (5.06e-2)" "unprognostic (2.76e-1)" "unprognostic (6.08e-2)" "prognostic favorable (9.80e-7)" "unprognostic (2.22e-1)" "unprognostic (3.37e-1)" "unprognostic (1.13e-1)" "unprognostic (9.57e-2)" 9.4 8.4 13.5 5.5 14.5 7.6 7.2 15.9 14.0 9.1 3.5 9.9 4.3 10.8 5.9 9.5 6.8 6.6 17.1 13.7 16.0 12.9 18.6 7.6 5.1 8.5 9.7 10.8 5.1 10.0 4.6 7.1 11.1 9.4 7.5 13.4 6.3 8.6 78.9 6.3 4.6 12.5 8.0 5.6 5.0 8.6 16.3 6.9 12.8 62.0 5.4 7.7 5.7 10.3 10.8 9.9 12.1 15.1 21.7 18.5 10.0 11.7 15.3 9.4 8.7 8.4 3.5 10.2 11.1 23.6 12.6 5.5 14.1 10.6 14.9 7.9 8.6 13.1 10.4 5.3 11.5 9.9 7.7 13.5 11.2 13.4 9.4 13.1 16.6 2.3 12.0 2.1 17.2 4.4 3.9 6.4 12.3 5.4 10.0 6.7 22.4 9.3 9.6 17.2 5.5 10.9 20.6 12.8 10.6 15.2 7.7 7.8 19.1 14.4 8.2 14.3 7.4 8.6 10.8 7.4 9.8 6.6 9.5 0.3 0.7 0.9 0.5 0.3 0.6 0.6 0.7 0.4 0.7 0.5 1.1 0.8 1.7 0.6 0.6 0.4 1.0 0.3 13.5 14.5 15.9 14.0 13.7 16.0 8.5 9.7 11.1 8.0 16.3 10.3 26.8 25.6 28.8 29.0 13.4 11.3 10.5 12.1 10.2 49.5 13.6 11.9 88.3 20.0 14.0 14.7 20.9 24.6 6.9 37.2 7.9 12.2 5.7 13.2 40.9 22.1 10.2 9.0 72.4 11.1 12.0 26.3 12.2 18.6 8.2 32.0 32.5 107.7 20.6 97.6 82.6 11.4 14.2 37.5 11.8 7.9 24.5 21.5 21.4 36.5 21.9 21.6 4.1 46.3 52.0 16.3 17.9 30.9 11.6 26.0 14.0 30.0 11.1 24.4 26.3 35.7 25.9 11.4 23.7 17.3 14.6 34.8 9.7 19.5 15.5 19.0