Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" AASS "LKRSDH, LORSDH" ENSG00000008311 "Aminoadipate-semialdehyde synthase" Q9UDR5 7 122064583-122144308 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 44.3" "Cell type enhanced" "Detected in many" "Astrocytes: 145.9;Hepatocytes: 113.9;Oligodendrocyte precursor cells: 106.1;Oligodendrocytes: 132.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 41.5;NTERA-2: 55.3;SuSa: 37.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020637, HPA020728, HPA020734" Enhanced Approved Nucleoplasm,Vesicles,Mitochondria Yes No 19000 "Cluster 15: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" Mitochondria "Nucleoplasm, Vesicles" "HPA020637: AB_1844415, HPA020728: AB_1844416, HPA020734: AB_1844417" "unprognostic (4.84e-2)" "unprognostic (2.29e-1)" "unprognostic (7.91e-4)" "unprognostic (6.08e-2)" "unprognostic (1.49e-2)" "unprognostic (8.00e-2)" "prognostic favorable (9.81e-4)" "unprognostic (4.48e-3)" "unprognostic (2.38e-1)" "unprognostic (1.47e-1)" "unprognostic (1.98e-1)" "unprognostic (1.99e-1)" "unprognostic (7.76e-3)" "unprognostic (8.56e-3)" "unprognostic (1.55e-1)" "unprognostic (6.50e-2)" "unprognostic (2.67e-1)" 9.7 5.9 10.0 1.8 12.2 0.2 8.4 10.3 14.4 8.2 15.5 5.2 0.9 9.5 7.5 3.2 11.7 2.1 9.2 9.4 10.6 13.9 44.3 6.3 1.4 11.6 11.0 25.2 4.8 7.1 3.5 3.2 11.4 5.4 1.4 3.7 3.5 4.8 8.6 2.8 3.6 4.4 10.1 2.9 5.5 2.2 11.0 1.5 4.7 6.2 1.4 6.9 6.2 11.8 0.1 0.0 21.9 41.5 27.3 13.5 9.4 5.4 8.0 7.3 9.1 12.6 0.1 0.0 0.2 6.6 8.3 4.1 33.5 16.8 9.6 0.0 12.2 9.4 4.3 12.5 22.0 0.0 2.9 12.2 0.5 9.2 7.1 18.9 19.8 12.1 2.7 15.5 5.1 0.1 0.9 0.0 55.3 0.1 1.7 11.8 16.3 0.3 5.3 2.4 2.7 0.7 1.5 0.0 5.3 37.8 0.5 0.0 8.1 13.6 3.4 7.0 8.3 3.5 3.0 0.0 4.9 0.8 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 10.0 12.2 10.3 14.4 9.4 10.6 11.6 11.0 11.4 10.1 11.0 11.8 16.0 9.6 37.8 145.9 2.1 6.2 9.0 2.8 14.8 7.0 8.7 6.3 9.7 14.3 5.6 14.7 16.7 11.6 1.5 0.6 0.0 2.7 12.2 4.1 24.0 11.7 3.0 5.2 5.0 1.8 3.3 14.4 5.6 7.7 3.8 18.1 24.7 113.9 1.5 11.8 4.4 2.6 2.0 2.2 2.5 7.4 19.0 1.4 12.4 35.6 0.0 8.9 0.0 106.1 132.5 2.3 2.5 24.5 1.6 4.7 5.4 8.6 0.9 3.3 19.7 38.9 15.8 12.4 2.4 7.8 4.7 5.1 2.1 8.0 1.9 4.8 ABCB7 "ABC7, ASAT, Atm1p, EST140535" ENSG00000131269 "ATP binding cassette subfamily B member 7" O75027 X 75051048-75156732 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034982 Approved Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA034982: AB_10601010" "unprognostic (1.05e-2)" "unprognostic (1.45e-1)" "unprognostic (1.49e-2)" "unprognostic (1.83e-3)" "unprognostic (4.44e-3)" "unprognostic (1.33e-2)" "unprognostic (6.31e-2)" "unprognostic (4.39e-2)" "unprognostic (1.47e-1)" "unprognostic (2.17e-1)" "unprognostic (4.14e-2)" "unprognostic (2.55e-2)" "prognostic favorable (5.31e-6)" "unprognostic (1.95e-1)" "unprognostic (1.27e-1)" "unprognostic (1.45e-1)" "unprognostic (1.08e-1)" 12.6 13.5 5.0 7.7 5.9 11.1 11.8 8.2 7.6 11.4 9.8 13.8 16.0 10.9 5.0 11.6 11.2 7.4 22.0 5.5 6.1 10.1 14.8 9.8 12.0 6.4 6.0 12.3 9.6 11.0 8.6 7.5 6.2 8.5 9.6 9.8 10.0 6.9 31.4 12.9 11.8 8.8 6.1 10.9 12.3 4.1 5.4 14.0 9.5 22.2 11.1 10.5 10.9 6.8 17.0 16.2 12.2 20.9 14.1 25.5 7.0 8.9 14.6 12.3 22.4 18.5 24.5 25.8 22.8 9.2 21.2 18.8 25.6 18.5 12.0 26.0 33.2 16.8 29.2 17.3 8.2 24.7 13.7 15.9 16.3 12.8 16.7 21.3 23.1 26.2 18.9 31.1 9.8 10.5 24.4 26.1 26.8 26.3 30.5 21.4 26.9 30.5 12.7 13.2 17.7 14.1 27.4 23.5 17.8 20.0 10.2 22.9 10.3 11.3 22.9 23.2 12.4 10.1 27.5 21.2 10.1 35.8 9.4 9.6 26.9 10.0 15.7 25.6 16.6 24.7 16.7 16.7 29.0 28.2 28.7 21.1 2.4 17.5 20.4 18.2 27.2 19.2 5.0 5.9 8.2 7.6 5.5 6.1 6.4 6.0 6.2 6.1 5.4 6.8 12.0 9.6 10.4 48.0 26.6 15.8 14.5 16.0 19.9 10.9 10.9 9.9 46.8 14.3 14.2 11.0 6.2 23.0 19.0 8.2 11.7 17.5 0.4 8.4 12.8 11.9 13.8 26.9 37.9 13.5 11.6 13.9 9.7 10.1 22.2 20.6 9.3 11.8 20.1 25.2 39.0 10.5 8.2 26.1 16.7 0.8 14.6 19.2 10.6 45.0 22.9 12.4 6.2 43.7 46.6 11.6 7.9 13.2 14.3 10.6 15.9 19.9 10.7 7.9 32.9 19.6 13.8 5.5 10.9 16.1 16.1 22.3 14.5 19.2 17.9 11.9 ABHD10 FLJ11342 ENSG00000144827 "Abhydrolase domain containing 10, depalmitoylase" Q9NUJ1 3 111979010-111993368 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036991, HPA036992, HPA066081" Supported Approved Mitochondria "Intracellular and membrane" No No 71000 "Cluster 46: Basophils - DNA binding" "Cluster 7: Kidney - Transmembrane transport" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA036991: AB_2675420, HPA036992: AB_10672345, HPA066081: AB_2685610" "unprognostic (1.65e-1)" "prognostic favorable (7.57e-4)" "unprognostic (1.61e-1)" "unprognostic (1.63e-1)" "unprognostic (1.05e-1)" "unprognostic (1.30e-2)" "unprognostic (8.95e-2)" "unprognostic (1.14e-1)" "unprognostic (8.50e-2)" "unprognostic (1.69e-2)" "unprognostic (1.70e-1)" "unprognostic (3.91e-2)" "prognostic favorable (4.72e-9)" "unprognostic (1.59e-2)" "unprognostic (1.72e-1)" "unprognostic (4.18e-3)" "unprognostic (2.76e-2)" 11.0 21.9 23.0 10.6 25.3 10.9 15.0 24.5 29.3 11.3 22.9 14.1 11.7 11.1 50.8 8.2 14.9 10.1 25.0 23.9 24.6 49.4 34.4 10.1 17.9 23.5 23.2 19.8 13.7 16.7 27.9 10.8 23.7 20.4 14.7 27.0 25.5 13.7 14.1 10.0 10.3 10.0 24.4 14.6 14.9 16.4 26.3 21.8 31.1 19.6 16.2 9.5 8.3 25.3 40.2 34.1 36.4 12.0 20.5 27.5 19.8 41.4 21.5 33.0 31.7 35.3 22.4 36.0 22.6 17.2 22.7 21.6 16.3 23.0 44.9 12.1 20.6 29.7 15.4 30.7 16.3 60.3 30.4 16.9 16.7 17.0 42.4 22.7 35.9 42.1 13.9 14.9 36.7 13.7 56.9 27.9 23.7 43.8 53.2 50.9 23.4 16.7 34.6 17.1 24.6 17.9 33.2 23.7 39.8 14.3 26.8 21.8 20.6 19.7 25.3 14.4 21.7 23.6 9.0 61.4 20.1 32.4 21.5 29.4 16.5 25.2 9.8 21.6 16.8 26.2 12.2 11.3 28.1 21.6 15.4 13.9 2.5 11.4 17.3 17.8 13.2 16.1 23.0 25.3 24.5 29.3 23.9 24.6 23.5 23.2 23.7 24.4 26.3 25.3 9.1 0.0 7.2 11.1 19.7 7.0 10.2 12.1 14.2 21.8 12.7 10.9 26.1 7.2 12.4 11.0 8.4 19.2 16.1 7.0 35.2 5.2 1.0 11.1 10.3 8.8 12.1 24.2 16.0 7.8 14.9 12.3 12.8 6.8 9.5 9.5 10.0 26.2 14.1 42.1 16.2 13.4 6.1 19.5 7.0 3.0 10.5 11.0 10.6 15.0 10.7 20.4 12.3 14.6 15.6 5.4 4.0 7.5 25.0 5.1 7.0 42.5 19.5 16.2 0.0 7.9 8.9 29.7 37.0 13.6 8.2 5.5 14.6 19.2 12.1 4.5 AC005833.1 ENSG00000255639 "Novel protein" 12 4649101-4774184 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 23.1;tongue: 18.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA012638, HPA042268, HPA073212" Supported Approved Nucleoplasm,Mitochondria No NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 2: Karpas-707 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Mitochondria" "HPA012638: AB_2294503, HPA042268: AB_2677922, HPA073212: AB_2686581" "unprognostic (9.01e-2)" "unprognostic (1.36e-2)" "unprognostic (5.11e-2)" "unprognostic (2.54e-1)" "unprognostic (3.41e-1)" "unprognostic (1.55e-1)" "unprognostic (1.10e-1)" "unprognostic (1.31e-1)" "unprognostic (6.29e-3)" "unprognostic (2.94e-2)" "unprognostic (3.24e-1)" "unprognostic (4.16e-1)" 2.1 1.3 1.1 3.8 1.4 2.0 2.6 1.3 1.6 1.9 0.9 14.6 14.2 1.2 1.0 2.2 1.7 1.3 7.0 1.2 1.3 6.8 6.4 1.4 1.7 1.3 1.3 1.0 0.5 7.0 1.9 1.4 1.8 23.1 0.7 2.5 2.4 2.2 1.0 14.5 3.2 1.3 1.3 2.6 3.4 1.3 2.9 1.6 18.4 3.4 2.8 1.5 4.4 7.0 5.1 3.4 3.4 3.5 11.8 3.7 5.2 10.4 8.6 13.6 7.6 8.8 1.0 5.7 6.5 6.0 9.3 6.4 11.9 8.9 5.0 10.0 7.4 8.9 7.1 9.6 3.0 5.0 6.0 5.6 10.2 4.0 10.6 5.9 7.0 19.9 7.8 5.0 3.6 3.3 16.5 10.2 2.2 6.5 9.6 6.0 8.6 8.2 2.7 2.3 5.3 9.5 4.6 11.7 1.8 3.0 5.1 4.7 9.5 2.5 8.3 1.3 4.6 10.6 3.5 4.5 4.5 3.6 7.4 2.6 5.2 7.4 5.9 6.0 4.9 5.7 9.6 3.9 4.1 4.0 0.3 5.6 6.9 8.7 6.7 14.7 1.1 1.4 1.3 1.6 1.2 1.3 1.3 1.3 1.4 1.3 1.3 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC007325.2 ENSG00000277196 "Proline dehydrogenase 1, mitochondrial" Unmapped 138082-161852 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "brain: 113.8;choroid plexus: 218.6" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 5.9;Distal tubular cells: 7.9;Endometrial ciliated cells: 2.5;Proximal enterocytes: 5.6;Squamous epithelial cells: 2.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "OE19: 345.1;RPTEC TERT1: 183.1" HPA020361 Uncertain Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Mitochondria "Nucleoplasm, Vesicles" "HPA020361: AB_10963116" 2.2 0.6 83.9 0.8 83.5 0.7 3.3 75.2 113.8 1.0 218.6 1.1 28.9 0.5 0.1 6.8 1.4 0.4 9.5 90.0 76.6 12.3 6.0 18.8 1.0 87.3 82.6 0.0 0.1 0.1 0.9 72.0 0.9 1.4 1.9 0.7 2.4 10.2 32.6 33.2 0.2 74.5 0.7 0.8 1.9 85.0 5.6 4.5 24.0 6.4 1.9 72.3 0.0 8.3 0.3 2.5 5.0 0.0 1.6 0.0 0.0 0.0 0.0 5.3 1.8 0.0 0.5 0.0 0.2 10.0 18.8 0.5 0.0 0.0 0.7 0.0 0.2 0.9 3.6 0.0 0.1 0.4 18.5 0.0 1.0 0.0 0.0 0.3 0.0 0.1 0.0 1.5 0.2 0.0 17.5 345.1 0.0 0.1 0.1 0.0 183.1 0.7 0.4 0.5 0.0 6.9 1.5 18.8 20.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 83.9 83.5 75.2 113.8 90.0 76.6 87.3 82.6 72.0 74.5 85.0 72.3 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 2.5 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.7 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 5.6 1.4 0.0 0.0 0.0 0.0 0.2 0.0 0.2 2.3 0.0 0.0 0.0 0.0 0.2 0.1 AC011455.2 ENSG00000269547 "Novel protein" 19 38915404-38949855 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "A549: 1.0" "HPA052730, HPA056957" Uncertain Uncertain Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 6: T47d - Mammary gland" "Nucleoplasm, Mitochondria" Vesicles "HPA052730: AB_2681929, HPA056957: AB_2683286" "unprognostic (6.10e-2)" "unprognostic (3.79e-2)" 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.2 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.8 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC012213.5 ENSG00000285982 "Novel protein" 8 103398658-103501895 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "retina: 6.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 5.8;SCLC-21H: 17.6" HPA024763 Approved Nucleoplasm,Mitochondria NA NA "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 11: Alveolar cells - Smell perception" Mitochondria Nucleoplasm "HPA024763: " 0.3 2.7 2.1 1.3 2.3 2.7 0.6 4.8 2.6 0.9 0.9 0.7 0.7 1.0 0.8 1.2 0.8 1.3 0.8 1.9 2.9 0.5 0.6 0.6 1.2 2.3 2.1 0.9 0.9 0.6 1.1 2.5 1.6 1.6 6.8 1.1 0.7 0.4 2.0 1.3 1.5 0.8 0.6 1.5 4.9 2.2 0.2 2.9 0.1 1.3 0.9 2.0 0.2 0.8 5.8 0.6 0.0 0.7 0.4 0.2 0.2 0.5 0.9 0.6 0.6 0.0 0.2 1.0 1.1 0.8 0.7 1.7 0.5 0.2 0.2 0.6 1.3 0.2 0.0 0.6 0.4 1.6 1.4 0.2 0.9 3.9 0.3 1.3 0.3 2.2 0.2 0.2 1.2 0.3 2.5 0.6 0.2 0.2 0.8 0.2 0.8 2.9 17.6 2.6 0.0 0.4 0.6 2.4 0.5 0.1 0.4 1.2 0.4 0.1 0.5 0.6 0.6 0.3 0.8 1.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.3 4.8 2.6 1.9 2.9 2.3 2.1 2.5 0.8 2.2 2.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC131160.1 ENSG00000283765 "Presenilin associated rhomboid like" 3 183815568-183884889 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.2;skeletal muscle: 5.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "T-47d: 15.8" HPA019545 Uncertain Approved Mitochondria NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 6: T47d - Mammary gland" "Cluster 11: Alveolar cells - Smell perception" Mitochondria "HPA019545: AB_1855796" 0.5 0.5 5.0 0.4 7.2 0.5 0.3 7.7 9.2 0.2 3.1 0.5 0.1 0.1 0.0 0.6 0.2 0.0 0.6 5.0 5.7 0.2 0.2 0.3 0.2 7.0 6.6 0.3 2.0 0.4 0.1 0.2 6.7 0.2 0.5 1.0 0.3 0.4 5.5 0.6 0.3 0.4 5.2 0.2 0.4 1.3 6.1 1.7 0.3 1.6 0.2 0.4 0.2 8.3 1.0 0.4 1.3 0.4 0.3 0.3 0.1 0.9 0.4 1.3 0.5 3.3 0.1 1.1 0.3 0.8 1.7 0.0 4.2 0.8 2.1 1.4 1.5 1.6 0.9 0.8 0.0 1.0 0.3 0.6 0.6 1.0 0.0 0.8 0.0 2.7 0.3 1.1 2.0 2.5 3.1 0.7 3.2 0.0 0.5 2.2 1.1 2.1 0.3 1.6 2.3 1.4 0.7 1.2 1.4 0.2 15.8 0.2 0.0 0.1 1.6 0.3 1.5 2.0 2.6 2.1 0.5 2.2 0.6 0.0 0.2 0.6 0.1 0.1 0.1 0.2 0.1 0.2 0.0 0.0 0.1 0.1 0.2 0.0 0.2 0.2 0.0 0.1 5.0 7.2 7.7 9.2 5.0 5.7 7.0 6.6 6.7 5.2 6.1 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC253536.7 ENSG00000285762 "Novel protein, AP000351.4-DDT readtrhough" 22 23971378-23980469 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Alveolar cells type 2: 15.4;Club cells: 4.3;granulocytes: 3.8;Respiratory ciliated cells: 3.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 1.1;HaCaT: 1.0;hTERT-RPE1: 2.2;RH-30: 1.2" "HPA049871, HPA074115" Uncertain Approved Mitochondria NA NA "Cluster 23: AN3-CA - Transcription regulation" "Cluster 11: Alveolar cells - Smell perception" Mitochondria "HPA049871: AB_2680926, HPA074115: " 0.1 0.3 0.1 0.3 0.1 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.3 0.3 0.1 0.0 0.3 0.2 0.0 0.4 0.4 0.1 0.5 0.0 0.4 0.3 0.0 0.0 0.2 0.8 0.0 0.5 0.0 0.2 0.0 0.0 0.2 0.2 0.1 0.3 0.0 0.1 0.0 0.0 0.1 0.5 0.2 0.0 0.0 1.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.9 1.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.3 0.0 0.0 0.8 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.3 0.1 0.4 0.4 0.3 0.0 0.3 0.5 0.0 6.4 15.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 ACO1 "IREB1, IREBP, IRP1" ENSG00000122729 "Aconitase 1" P21399 9 32384603-32454769 "Cancer-related genes, Citric acid cycle related proteins, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" "Lyase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 134.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 194.4;Proximal tubular cells: 183.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 194.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019371, HPA024157" Enhanced Supported Mitochondria,Cytosol NA NA 10000000 "Cluster 38: Basophils - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Mitochondria, Cytosol" "HPA019371: AB_1844519, HPA024157: AB_1844520" "unprognostic (2.11e-1)" "unprognostic (5.61e-2)" "unprognostic (8.38e-2)" "unprognostic (9.12e-2)" "unprognostic (2.63e-1)" "unprognostic (3.12e-2)" "unprognostic (4.25e-3)" "unprognostic (2.61e-2)" "unprognostic (1.37e-1)" "unprognostic (1.19e-1)" "unprognostic (2.55e-1)" "unprognostic (3.08e-1)" "prognostic favorable (5.73e-5)" "unprognostic (2.54e-1)" "unprognostic (6.58e-2)" "unprognostic (1.65e-1)" "unprognostic (3.23e-2)" 96.6 50.5 15.2 16.1 15.4 3.5 50.1 14.6 15.3 19.8 19.1 23.7 48.6 19.2 30.2 15.4 14.6 15.6 36.3 14.0 16.2 89.2 134.5 20.3 8.8 15.8 15.8 17.4 37.6 22.8 13.1 16.1 14.9 21.9 20.6 12.9 16.6 19.1 25.1 12.0 35.8 22.9 15.3 9.3 28.7 17.6 16.9 13.6 34.5 37.8 7.1 24.4 13.7 14.1 37.5 33.7 25.7 40.7 194.5 104.8 11.6 69.3 169.1 31.2 24.5 36.0 11.4 7.4 21.6 73.1 84.9 5.1 51.3 66.3 62.3 23.8 13.8 54.7 33.4 39.3 97.4 5.1 21.2 91.7 20.1 80.4 56.1 95.6 81.7 28.4 20.0 15.7 89.9 9.9 29.5 26.4 26.9 23.3 35.5 22.8 38.0 7.8 118.9 34.1 3.3 10.5 71.9 2.8 7.6 27.1 16.7 13.5 89.2 112.5 38.2 38.2 18.2 7.8 15.5 14.7 78.7 18.2 10.2 33.2 11.3 3.3 9.2 11.3 8.0 5.6 6.2 6.9 9.3 5.0 8.1 8.2 1.2 6.7 10.0 4.3 3.9 8.4 15.2 15.4 14.6 15.3 14.0 16.2 15.8 15.8 14.9 15.3 16.9 14.1 16.3 3.2 25.7 43.8 6.7 4.5 7.9 11.9 9.1 21.4 17.8 7.4 45.5 38.6 11.7 23.9 22.9 50.8 6.2 26.4 19.6 19.0 8.7 10.0 30.7 18.7 4.9 11.6 24.6 41.0 22.1 29.7 39.3 13.9 2.5 17.1 15.7 194.4 15.1 33.7 46.5 27.7 10.2 14.8 6.7 6.9 23.6 15.6 7.2 20.6 8.6 25.7 8.2 22.1 24.1 19.4 23.7 23.3 7.2 10.1 56.1 183.4 10.7 14.3 19.7 30.5 22.2 9.8 19.4 10.3 5.4 53.5 7.5 22.2 34.6 8.7 ACO2 ACONM ENSG00000100412 "Aconitase 2" Q99798 22 41447830-41529273 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Lyase "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 567.7;skeletal muscle: 660.4;tongue: 695.8" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 374.2;Proximal tubular cells: 285.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001097 Enhanced Approved Approved Mitochondria NA NA 2000000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA001097: AB_1078092" "unprognostic (1.95e-1)" "unprognostic (2.50e-2)" "unprognostic (2.35e-2)" "unprognostic (3.06e-2)" "unprognostic (6.51e-2)" "unprognostic (1.26e-1)" "unprognostic (3.99e-2)" "unprognostic (6.54e-2)" "unprognostic (1.20e-2)" "unprognostic (7.32e-2)" "unprognostic (1.64e-2)" "unprognostic (6.07e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.46e-2)" "unprognostic (9.60e-2)" "unprognostic (6.45e-2)" "unprognostic (1.12e-2)" 88.8 81.6 154.2 38.6 152.2 32.0 52.4 153.0 190.0 39.5 160.1 94.4 162.9 42.0 26.1 60.4 53.6 36.5 567.7 155.2 153.1 138.9 73.9 40.7 40.5 146.1 145.3 30.8 53.8 233.8 33.6 30.5 147.8 41.2 69.6 46.9 72.0 49.5 660.4 45.5 158.5 43.7 152.5 44.7 110.2 35.1 186.3 38.0 53.7 695.8 43.3 52.5 42.4 159.6 47.2 55.8 56.5 116.3 101.2 69.8 78.7 43.7 60.9 79.0 71.9 81.2 63.5 115.7 72.2 70.6 60.3 109.8 108.8 88.3 42.8 75.8 80.2 51.0 73.7 95.0 86.7 147.8 77.8 120.8 64.4 78.9 83.2 61.7 81.2 61.5 72.9 118.4 65.4 91.7 73.7 47.9 37.0 282.6 115.1 102.3 37.8 162.1 106.8 97.3 37.8 33.9 112.2 128.7 82.0 44.9 74.9 74.7 55.5 60.0 68.7 50.2 45.0 64.7 92.1 80.6 102.0 64.0 66.5 10.3 52.9 18.1 32.0 76.4 29.3 49.4 25.5 34.9 69.0 46.4 29.2 30.8 9.0 39.4 97.1 24.0 41.2 58.6 154.2 152.2 153.0 190.0 155.2 153.1 146.1 145.3 147.8 152.5 186.3 159.6 26.3 25.6 31.8 45.4 49.4 18.7 54.5 102.7 31.3 60.6 28.0 23.2 9.1 64.3 63.5 60.7 81.3 100.3 33.3 190.8 131.0 58.3 14.5 37.2 17.7 26.1 53.2 30.3 28.8 42.6 60.0 24.0 77.5 37.1 40.6 56.7 20.7 64.6 91.5 53.8 34.0 99.1 89.5 35.5 26.4 8.9 24.2 39.2 35.6 7.5 68.3 73.9 34.0 12.1 20.9 43.9 103.5 27.8 63.2 34.4 374.2 285.7 59.2 73.5 59.2 28.6 38.4 26.4 38.2 35.8 16.1 193.2 30.7 54.4 113.6 64.9 ACOT1 "ACH2, CTE-1, LACH2" ENSG00000184227 "Acyl-CoA thioesterase 1" Q86TX2 14 73537143-73543796 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 44.4" "Cell type enhanced" "Detected in some" "Astrocytes: 10.7;Cardiomyocytes: 51.5;Excitatory neurons: 13.8;Inhibitory neurons: 12.0;Oligodendrocyte precursor cells: 8.5;Oligodendrocytes: 15.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 30.5;T-47d: 49.8" HPA043705 Approved Approved Mitochondria NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA043705: AB_2678626" "unprognostic (4.74e-3)" "unprognostic (3.81e-3)" "unprognostic (7.65e-2)" "unprognostic (8.66e-2)" "unprognostic (1.22e-1)" "unprognostic (1.29e-1)" "unprognostic (4.54e-2)" "unprognostic (1.29e-2)" "unprognostic (1.53e-1)" "unprognostic (1.73e-2)" "unprognostic (1.84e-1)" "unprognostic (4.16e-1)" "prognostic favorable (5.09e-8)" "unprognostic (1.35e-3)" "unprognostic (4.60e-2)" "unprognostic (1.75e-1)" "unprognostic (1.43e-1)" 15.1 12.9 10.4 3.6 10.2 2.4 13.0 9.3 11.3 5.7 8.4 12.9 10.8 13.2 11.6 3.4 7.3 3.5 18.6 10.1 9.7 25.9 44.4 7.3 2.3 9.2 10.1 3.5 3.0 2.2 2.0 2.9 9.6 5.6 5.4 2.9 5.1 9.3 19.6 8.9 11.8 20.9 9.5 2.6 6.4 4.2 11.1 2.5 3.6 29.3 2.1 9.5 4.0 9.6 10.7 9.0 3.3 0.7 15.2 9.1 0.1 2.9 8.5 7.0 12.6 3.9 6.9 0.0 0.4 5.8 0.9 6.0 0.0 1.4 3.4 4.5 2.8 4.6 2.8 30.5 14.4 0.1 5.1 12.0 0.6 5.6 0.0 0.7 3.2 0.0 0.0 0.0 5.5 4.7 0.6 1.0 3.4 1.4 4.9 9.5 6.8 0.2 6.9 8.7 4.9 6.4 9.0 20.2 12.2 0.9 49.8 9.9 4.2 5.2 7.5 4.2 0.7 0.1 0.0 2.6 6.2 0.0 6.8 0.7 0.9 0.7 4.1 1.1 3.5 2.6 3.9 3.4 3.8 1.9 3.5 3.9 0.1 3.5 1.1 2.2 5.1 2.6 10.4 10.2 9.3 11.3 10.1 9.7 9.2 10.1 9.6 9.5 11.1 9.6 0.2 0.0 3.2 10.7 0.0 0.0 0.1 0.6 1.8 0.0 0.4 0.4 51.5 0.0 0.4 0.0 0.0 0.7 1.3 0.2 0.0 0.4 0.6 0.3 0.3 0.7 0.0 2.7 13.8 8.0 0.3 2.6 0.0 0.3 0.0 0.1 0.0 1.1 0.9 0.0 12.0 0.0 2.0 0.3 0.0 0.0 0.0 0.5 1.8 3.7 0.0 0.0 0.0 8.5 15.1 2.6 0.0 0.4 0.3 0.0 0.0 3.7 0.3 0.0 0.0 0.0 3.6 0.1 0.2 0.6 0.0 0.8 0.2 0.0 0.2 0.0 ACOT2 "Mte1, ZAP128" ENSG00000119673 "Acyl-CoA thioesterase 2" P49753 14 73567620-73575658 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 118.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 50.0;Exocrine glandular cells: 33.2;Proximal tubular cells: 36.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 62.4" "HPA043705, HPA060170" Enhanced Approved Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA043705: AB_2678626, HPA060170: AB_2732642" "unprognostic (4.44e-3)" "unprognostic (1.68e-2)" "unprognostic (3.17e-1)" "unprognostic (8.66e-2)" "unprognostic (1.78e-1)" "unprognostic (1.55e-1)" "unprognostic (2.78e-2)" "unprognostic (6.61e-2)" "unprognostic (4.10e-2)" "unprognostic (9.21e-2)" "unprognostic (6.42e-2)" "unprognostic (1.64e-1)" "prognostic favorable (2.28e-6)" "unprognostic (1.66e-3)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (4.35e-1)" 92.3 47.7 10.0 7.0 10.3 5.6 48.9 9.2 12.4 17.1 12.2 42.2 24.7 42.9 10.7 10.9 24.1 6.1 94.5 10.1 9.5 49.4 118.9 17.3 4.7 8.8 9.4 11.7 12.8 22.4 8.3 4.4 8.2 17.8 11.1 4.1 17.8 11.1 114.0 13.1 24.5 22.8 9.2 11.4 22.5 12.0 13.0 3.7 14.5 50.0 3.3 31.2 13.3 9.0 22.8 25.0 4.9 22.1 21.3 7.9 1.0 13.7 31.5 21.9 28.6 18.1 12.6 0.1 9.7 7.0 10.3 12.7 0.0 1.2 11.4 33.1 31.6 16.0 7.6 62.4 14.5 0.1 43.3 19.5 0.0 7.6 0.1 21.0 9.5 0.0 0.0 0.1 18.7 7.4 2.5 18.2 7.5 2.3 37.8 37.2 21.9 0.3 8.0 9.5 21.6 27.3 33.1 24.3 29.6 2.1 51.1 12.7 17.0 17.9 47.2 11.8 13.0 0.0 0.1 9.5 15.8 0.1 18.2 3.5 5.9 3.1 22.1 7.0 15.8 15.0 20.2 16.6 21.9 12.4 17.8 19.9 0.2 15.3 6.5 13.6 31.3 13.6 10.0 10.3 9.2 12.4 10.1 9.5 8.8 9.4 8.2 9.2 13.0 9.0 4.3 0.0 6.4 3.3 6.6 1.7 1.0 5.9 16.5 1.1 5.2 4.2 50.0 7.2 3.0 7.3 10.4 6.1 3.0 20.1 13.7 20.9 1.5 1.4 1.9 4.0 15.7 8.4 2.9 33.2 3.2 7.0 11.7 2.1 13.4 1.9 4.2 27.7 14.9 1.7 3.1 15.5 10.2 3.8 1.6 1.1 5.9 5.6 5.4 1.0 18.5 5.5 7.2 3.0 1.7 21.8 8.6 8.2 7.9 0.4 27.5 36.5 3.3 4.9 6.6 1.4 9.8 0.3 4.8 8.5 0.4 8.2 5.8 1.7 18.8 0.4 ACOT8 "hACTE-III, hTE, NAP1, PTE-2, PTE1" ENSG00000101473 "Acyl-CoA thioesterase 8" O14734 20 45841721-45857405 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Host-virus interaction, Lipid metabolism, Peroxisome biogenesis" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 104.2;Late spermatids: 90.3;Proximal enterocytes: 105.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010261 Approved Supported Vesicles,Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles Mitochondria "CAB010261: AB_2221664" "unprognostic (2.36e-2)" "unprognostic (6.95e-2)" "unprognostic (2.12e-1)" "unprognostic (1.28e-2)" "unprognostic (2.13e-1)" "unprognostic (4.27e-1)" "unprognostic (1.03e-3)" "unprognostic (2.92e-2)" "unprognostic (4.70e-1)" "unprognostic (1.72e-1)" "unprognostic (2.28e-2)" "unprognostic (2.03e-2)" "prognostic favorable (3.18e-4)" "unprognostic (2.79e-1)" "unprognostic (1.23e-1)" "unprognostic (4.61e-2)" "unprognostic (2.98e-1)" 8.3 31.7 27.8 8.6 29.8 18.1 7.6 28.2 35.2 9.3 24.3 18.5 21.1 8.5 11.0 17.5 10.7 9.2 28.1 29.8 28.6 21.3 26.0 11.0 12.6 27.0 28.5 8.0 15.6 15.1 15.4 7.1 28.7 12.7 12.8 9.2 12.8 5.9 28.7 17.0 20.5 6.4 26.0 12.3 21.3 20.2 28.7 13.1 11.4 17.8 9.7 11.0 10.4 28.1 16.8 20.2 6.8 13.4 18.3 11.0 11.7 11.1 9.5 15.1 13.7 29.2 22.7 20.8 48.2 16.3 35.4 32.3 13.0 27.8 6.6 15.5 22.3 21.2 25.1 28.5 16.9 19.9 19.3 12.9 21.3 15.1 10.9 22.6 9.4 23.6 18.8 24.2 11.0 47.4 28.7 27.0 11.8 32.4 52.2 14.0 12.2 37.6 16.5 19.1 23.1 10.8 24.9 61.7 39.5 10.6 34.4 48.8 11.6 37.9 8.5 19.5 18.9 20.7 33.8 14.0 46.3 21.2 20.8 34.3 34.3 43.6 24.8 34.6 21.8 27.5 23.2 21.9 36.7 27.9 20.0 21.6 25.0 16.3 34.2 23.3 31.9 26.7 27.8 29.8 28.2 35.2 29.8 28.6 27.0 28.5 28.7 26.0 28.7 28.1 8.2 35.3 14.1 5.9 17.9 6.1 12.3 21.9 8.6 19.2 9.8 10.9 9.3 11.5 17.7 12.9 16.7 34.2 11.8 104.2 64.6 21.6 38.5 14.2 10.4 10.9 19.2 17.0 12.3 21.0 20.9 11.4 19.9 14.0 14.0 27.6 11.4 25.5 27.8 8.4 12.0 37.3 10.2 18.6 7.1 90.3 9.9 17.5 10.6 3.7 27.5 17.8 34.0 5.0 9.6 21.6 68.4 8.6 21.3 11.3 105.4 81.5 27.1 22.8 13.1 5.8 12.8 27.0 10.2 16.1 8.0 19.4 13.9 37.6 30.3 16.0 ACSL4 "ACS4, FACL4, LACS4, MRX63, MRX68" ENSG00000068366 "Acyl-CoA synthetase long chain family member 4" O60488 X 109624244-109733403 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Alport syndrome, Deafness, Disease variant, Elliptocytosis, Hereditary hemolytic anemia, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 184.3;Glandular and luminal cells: 208.8;granulocytes: 633.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 360.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000286, HPA005552" Supported Approved "Golgi apparatus,Mitochondria" NA NA 16000 "Cluster 2: Granulocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Golgi apparatus" Mitochondria "HPA000286: AB_2665966, HPA005552: AB_1078774" "unprognostic (9.13e-2)" "unprognostic (3.38e-1)" "unprognostic (1.39e-1)" "unprognostic (2.61e-1)" "unprognostic (2.55e-1)" "unprognostic (2.94e-2)" "unprognostic (5.32e-2)" "unprognostic (4.14e-3)" "unprognostic (1.92e-1)" "unprognostic (9.45e-2)" "unprognostic (1.92e-2)" "unprognostic (1.21e-1)" "unprognostic (1.64e-2)" "unprognostic (1.81e-1)" "unprognostic (4.78e-1)" "unprognostic (3.29e-2)" "prognostic favorable (5.73e-4)" 44.2 40.6 11.9 38.8 14.1 16.2 19.8 13.2 14.8 48.2 5.6 12.7 15.4 19.2 17.7 15.8 13.4 29.2 29.4 16.5 23.7 46.4 13.9 39.0 24.6 17.6 20.8 14.9 11.9 19.8 9.2 21.4 21.3 13.4 13.6 24.7 10.6 15.2 42.6 9.9 13.4 22.0 13.7 22.2 19.3 26.8 14.6 20.3 18.6 16.9 18.5 68.0 10.6 18.9 67.3 21.3 24.2 28.3 97.8 61.6 20.3 94.0 107.6 91.0 97.4 21.1 45.0 46.2 35.4 71.7 100.9 19.4 22.4 92.0 143.0 15.7 23.3 181.4 26.6 223.3 44.8 44.8 360.0 51.4 36.7 103.6 74.0 50.2 71.8 25.5 5.6 54.2 100.7 4.7 40.7 60.7 31.6 15.2 37.2 26.4 45.4 39.6 136.3 20.9 15.2 12.3 109.3 0.4 63.2 49.0 1.9 45.8 128.5 81.1 22.6 129.3 85.9 28.1 31.7 41.2 139.7 97.8 52.2 32.5 10.9 35.0 4.2 15.5 3.2 3.3 3.9 3.5 10.6 3.1 3.0 3.8 29.6 4.0 19.4 4.0 6.7 6.5 11.9 14.1 13.2 14.8 16.5 23.7 17.6 20.8 21.3 13.7 14.6 18.9 27.9 76.9 184.3 29.0 19.5 22.3 25.7 20.0 81.4 44.2 7.3 8.1 37.2 15.7 40.1 73.5 2.1 7.3 18.3 0.8 50.9 27.7 1.4 79.5 27.0 29.8 7.7 26.1 76.7 25.4 36.9 46.0 7.1 208.8 633.8 151.6 18.2 44.2 23.9 6.7 78.3 5.7 2.0 64.9 59.1 4.9 5.6 67.8 16.0 57.1 70.4 10.9 8.2 71.4 116.4 32.3 3.0 10.1 36.1 19.4 0.7 12.4 12.2 16.7 0.0 20.0 27.9 3.7 5.3 10.1 8.1 31.6 25.2 34.9 2.7 18.4 ADAM28 "ADAM23, eMDCII, MDC-Lm, MDC-Ls" ENSG00000042980 "ADAM metallopeptidase domain 28" Q9UKQ2 8 24294069-24359014 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "epididymis: 357.5;stomach 1: 110.3" "Cell type enhanced" "Detected in many" "B-cells: 240.9;Club cells: 62.9;Gastric mucus-secreting cells: 141.7;Microglial cells: 233.3" "Cancer enhanced" "Detected in many" "pancreatic cancer: 9.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 71.6;naive B-cell: 87.0" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "CAPAN-2: 27.8;OE19: 8.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA074034 Enhanced Approved "Plasma membrane,Mitochondria" "Secreted to blood" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 57: B-cells - Immune response" "Plasma membrane" Mitochondria "HPA074034: AB_2686654" "unprognostic (4.23e-2)" "unprognostic (1.01e-2)" "unprognostic (2.06e-2)" "prognostic favorable (3.17e-4)" "unprognostic (2.89e-1)" "unprognostic (2.55e-2)" "unprognostic (5.59e-2)" "unprognostic (1.53e-1)" "unprognostic (4.71e-1)" "unprognostic (1.35e-2)" "unprognostic (3.77e-3)" "unprognostic (7.77e-2)" "unprognostic (3.97e-3)" "unprognostic (1.71e-2)" "unprognostic (1.30e-1)" "unprognostic (2.60e-1)" "unprognostic (1.62e-1)" 2.2 2.2 5.9 24.7 4.6 9.3 3.9 7.1 5.0 16.1 4.0 14.3 8.8 6.9 357.5 2.8 12.3 40.2 1.0 5.8 8.8 5.1 1.2 3.9 26.7 12.0 9.3 2.3 3.5 1.1 18.5 3.7 11.7 5.3 12.1 1.3 15.9 5.7 0.3 3.3 24.7 2.9 9.8 19.9 110.3 0.7 10.1 5.1 1.9 0.4 32.3 11.3 1.7 18.6 0.0 0.4 0.1 0.0 0.0 0.4 0.1 0.1 0.2 0.0 0.0 1.1 27.8 0.3 0.8 0.0 0.9 0.1 0.0 0.8 0.1 0.1 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.2 3.7 0.7 8.8 0.1 0.1 0.0 0.4 0.6 0.8 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.5 0.3 0.1 0.1 1.2 2.5 0.1 2.1 1.0 0.2 42.4 2.5 18.5 0.0 0.6 0.0 71.6 0.1 0.0 21.0 87.0 0.1 0.0 4.3 2.7 0.2 1.1 0.1 2.5 5.9 4.6 7.1 5.0 5.8 8.8 12.0 9.3 11.7 9.8 10.1 18.6 1.5 3.2 6.0 0.7 240.9 0.9 3.0 36.9 0.0 0.1 2.3 2.2 2.0 28.6 62.9 3.7 0.0 0.4 9.9 0.7 0.0 7.9 1.3 7.6 1.0 3.7 0.0 8.2 4.3 3.5 8.7 3.9 141.7 18.4 2.5 0.0 0.0 0.0 9.4 0.0 2.7 0.4 28.5 12.3 30.9 1.8 0.6 46.4 5.4 233.3 7.8 0.1 23.7 3.5 1.6 55.7 0.1 0.4 43.3 1.5 0.6 4.4 13.1 0.1 6.6 0.0 1.1 0.4 0.2 0.7 0.6 0.5 9.0 6.4 1.3 7.6 ADAMTS12 ENSG00000151388 "ADAM metallopeptidase with thrombospondin type 1 motif 12" P58397 5 33523535-33892019 "Plasma proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 25.2;Fibroblasts: 22.9;Leydig cells: 22.1;Microglial cells: 73.1;Sertoli cells: 52.6;Theca cells: 55.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 47.4;hTERT-RPE1: 88.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA035973, HPA075079" Uncertain Approved Nucleoli,Mitochondria "Secreted to extracellular matrix" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 52: Non-specific - Transcription" Nucleoli Mitochondria "HPA035973: AB_10669663, HPA075079: AB_2732278" "unprognostic (6.18e-3)" "unprognostic (3.12e-4)" "unprognostic (1.05e-1)" "unprognostic (8.37e-2)" "unprognostic (1.65e-1)" "unprognostic (3.52e-1)" "unprognostic (2.60e-2)" "unprognostic (3.49e-3)" "unprognostic (3.78e-3)" "unprognostic (3.39e-2)" "unprognostic (5.63e-3)" "unprognostic (1.45e-1)" "unprognostic (4.27e-7)" "unprognostic (4.45e-3)" "unprognostic (1.47e-1)" "unprognostic (5.85e-2)" "prognostic unfavorable (6.78e-4)" 9.0 5.2 0.9 1.6 0.7 0.0 7.8 0.5 0.4 2.7 1.7 2.5 0.5 3.8 0.5 0.9 3.2 4.0 1.6 0.2 0.4 1.3 1.4 5.6 0.9 1.2 0.9 2.7 0.6 0.5 0.6 3.9 1.0 1.3 1.0 0.7 0.9 1.4 0.8 1.5 1.1 6.5 1.5 0.5 1.2 2.0 1.3 0.3 1.9 0.7 0.6 2.2 2.0 3.3 28.7 0.9 25.5 0.0 35.9 17.2 0.0 13.3 33.1 16.8 19.5 0.0 0.0 0.0 0.0 9.0 29.1 0.8 0.7 16.7 24.0 0.0 0.0 0.0 0.0 0.0 28.4 0.0 0.0 13.8 0.0 47.4 12.2 88.0 0.0 0.0 0.0 0.1 26.6 0.0 0.0 0.0 5.0 0.0 0.0 0.0 29.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 36.9 0.0 0.0 0.0 28.0 36.2 0.3 7.9 4.4 3.5 0.0 23.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.7 0.5 0.4 0.2 0.4 1.2 0.9 1.0 1.5 1.3 3.3 6.4 0.0 0.0 1.3 0.5 0.8 0.0 0.0 0.0 0.1 1.5 2.0 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 4.9 1.2 25.2 2.1 0.0 0.0 3.0 0.2 0.4 22.9 0.0 0.6 0.0 3.3 11.4 0.2 0.6 0.0 6.2 0.0 0.0 0.3 2.1 3.0 22.1 0.2 7.2 73.1 0.0 5.3 0.0 0.5 7.8 0.1 0.0 17.7 0.0 0.1 0.0 2.4 0.7 0.2 52.6 1.7 19.1 0.4 4.7 0.1 0.9 0.8 0.3 55.4 0.0 0.1 ADAMTS16 ADAMTS16s ENSG00000145536 "ADAM metallopeptidase with thrombospondin type 1 motif 16" Q8TE57 5 5140330-5320304 "Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.0;ovary: 10.4" "Cell type enhanced" "Detected in some" "Collecting duct cells: 7.3;Excitatory neurons: 44.7;Fibroblasts: 13.7;Granulosa cells: 22.2;Theca cells: 15.9" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 5 "cerebellum: 17.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 3.9;SuSa: 3.5;U-2197: 5.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA067668 Approved "Nucleoplasm,Nuclear membrane,Midbody ring,Mitochondria" "Secreted to extracellular matrix" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear membrane, Mitochondria" "Nucleoplasm, Midbody ring" "HPA067668: " "unprognostic (8.48e-2)" "unprognostic (1.19e-1)" "unprognostic (2.86e-2)" "unprognostic (1.98e-4)" "unprognostic (1.91e-2)" "unprognostic (5.04e-2)" "unprognostic (7.64e-2)" "unprognostic (7.80e-3)" "unprognostic (2.12e-2)" "unprognostic (5.44e-2)" "unprognostic (1.51e-2)" "unprognostic (2.18e-1)" "prognostic favorable (3.29e-5)" "unprognostic (1.20e-4)" "unprognostic (1.46e-1)" "unprognostic (4.59e-3)" "unprognostic (2.86e-3)" 5.4 0.2 1.4 0.4 1.9 0.5 0.7 17.0 2.6 1.4 0.0 0.7 0.6 1.3 1.6 1.5 0.7 6.4 0.2 3.4 0.0 3.5 0.4 0.7 0.2 0.2 0.2 10.4 4.5 0.1 0.0 0.2 0.7 0.1 0.3 1.2 0.2 0.5 0.2 0.4 0.5 1.1 0.0 0.2 0.2 0.4 0.0 0.2 0.3 0.2 0.1 1.0 0.6 1.8 1.7 1.7 1.7 0.1 0.1 0.3 0.2 0.0 0.0 0.4 0.5 0.0 1.4 0.1 2.1 0.0 3.0 0.1 0.0 0.0 0.4 0.1 0.9 0.3 2.8 0.0 0.0 0.2 0.0 0.0 0.0 3.9 0.1 0.5 0.0 0.3 0.6 0.4 0.7 0.0 0.4 0.2 1.1 0.0 1.6 0.4 2.2 0.1 0.0 0.1 0.5 0.1 0.1 0.1 0.1 3.5 0.1 0.1 0.1 2.1 3.0 5.8 1.4 0.9 0.3 0.1 3.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.4 1.9 17.0 2.6 3.4 0.0 0.2 0.2 0.7 0.0 0.0 1.8 0.7 0.0 0.6 2.6 0.0 0.0 0.0 0.0 0.6 2.0 0.7 0.4 0.5 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.2 5.0 0.1 0.0 0.0 44.7 0.0 0.0 13.7 0.5 0.5 0.0 22.2 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 2.8 0.0 0.0 0.0 1.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.7 0.0 6.9 1.6 0.1 0.0 0.0 0.0 0.0 0.1 15.9 0.0 0.0 ADCY1 "AC1, DFNB44" ENSG00000164742 "Adenylate cyclase 1" Q08828 7 45574140-45723116 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, cAMP biosynthesis" "Calmodulin-binding, Lyase" "Cancer-related genes, Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 33.7;liver: 19.2;retina: 53.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 521.3;Excitatory neurons: 147.2;Inhibitory neurons: 117.9;Rod photoreceptor cells: 174.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-HME1: 22.2;SH-SY5Y: 25.5;SK-MEL-30: 30.1;WM-115: 17.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018364, HPA068274" Uncertain Approved Mitochondria NA NA "Cluster 58: Brain - Synaptic function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 9: Photoreceptor cells - Phototransduction" Mitochondria "CAB018364: AB_2223098, HPA068274: " "unprognostic (9.41e-3)" "unprognostic (7.30e-4)" "unprognostic (9.31e-2)" "unprognostic (2.98e-1)" "unprognostic (4.18e-2)" "unprognostic (3.07e-3)" "unprognostic (1.32e-1)" "unprognostic (7.31e-2)" "unprognostic (1.64e-3)" "unprognostic (2.89e-1)" "unprognostic (7.73e-3)" "unprognostic (1.54e-1)" "unprognostic (4.74e-6)" "unprognostic (2.49e-1)" "unprognostic (7.65e-3)" "unprognostic (2.87e-1)" "unprognostic (2.23e-1)" 1.9 1.8 13.7 0.3 22.4 0.0 4.7 15.4 33.7 5.3 0.0 0.4 0.2 1.8 0.5 0.6 2.0 0.6 2.9 31.9 0.0 1.9 19.2 0.6 0.4 1.2 0.9 0.9 3.3 1.9 2.6 0.4 1.1 2.8 0.4 53.0 0.3 1.2 7.7 0.4 0.3 0.9 0.0 1.7 1.1 2.8 4.0 0.3 2.4 8.5 0.3 0.8 1.3 24.5 0.8 5.9 2.1 3.2 4.1 0.1 4.0 0.2 0.0 0.8 0.3 0.6 0.0 0.0 0.2 0.2 5.8 1.9 3.8 0.3 0.1 10.7 2.7 0.0 0.0 0.6 0.0 0.2 0.1 4.9 2.8 0.5 22.2 0.0 0.1 8.6 0.3 7.0 0.3 7.1 0.0 0.0 8.3 5.1 0.0 0.0 0.0 11.7 0.0 5.7 13.4 25.5 2.1 0.0 30.1 3.1 2.0 3.5 0.0 0.6 4.2 0.5 3.6 0.0 0.0 0.0 0.0 0.0 17.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.7 22.4 15.4 33.7 31.9 0.0 1.2 0.9 1.1 0.0 4.0 24.5 3.5 0.0 0.0 30.7 0.3 0.3 0.6 0.0 0.0 43.8 10.6 5.7 11.4 2.8 0.0 0.0 521.3 0.1 0.3 0.5 1.9 0.0 2.9 1.0 23.1 10.8 31.2 0.0 147.2 0.9 0.2 4.2 0.0 0.7 0.0 0.2 15.7 52.3 0.3 42.1 117.9 1.0 2.0 3.2 0.4 0.7 1.8 0.2 3.6 17.8 0.0 13.8 0.0 63.3 4.0 0.5 0.1 7.5 0.1 2.6 0.0 0.4 0.0 174.4 0.0 2.3 8.8 0.5 6.8 0.1 0.1 0.0 0.6 0.6 0.6 0.3 ADNP2 "KIAA0863, ZNF508" ENSG00000101544 "ADNP homeobox 2" Q6IQ32 18 80109262-80147523 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 41.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007126 Uncertain Approved Mitochondria,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" "Mitochondria, Cytosol" "HPA007126: AB_1080729" "unprognostic (4.93e-2)" "unprognostic (1.45e-1)" "unprognostic (1.05e-2)" "unprognostic (2.25e-1)" "unprognostic (1.25e-1)" "unprognostic (1.69e-1)" "unprognostic (3.42e-2)" "unprognostic (2.31e-1)" "unprognostic (1.24e-1)" "unprognostic (6.05e-2)" "unprognostic (3.40e-2)" "unprognostic (8.35e-2)" "prognostic favorable (6.39e-5)" "unprognostic (8.64e-2)" "unprognostic (3.59e-1)" "prognostic unfavorable (9.90e-4)" "unprognostic (5.19e-2)" 8.0 6.2 17.3 6.6 13.1 41.3 8.1 7.3 31.2 6.0 9.9 7.2 9.1 7.4 10.8 8.6 6.6 7.5 8.0 10.2 9.1 6.7 7.9 7.5 7.2 15.4 10.1 8.0 8.2 9.6 6.9 6.7 14.0 6.8 6.6 12.4 6.4 6.3 2.7 12.7 6.6 7.8 9.4 6.5 7.8 22.0 18.0 9.4 8.4 4.5 7.1 7.7 6.9 15.6 23.1 17.8 36.2 27.0 8.1 11.4 27.0 16.3 18.6 19.2 23.8 16.9 11.5 0.2 6.2 13.3 23.6 20.8 35.4 21.1 20.2 21.0 17.8 32.3 12.8 18.5 14.8 47.5 34.5 11.9 19.6 19.7 26.1 12.8 19.4 36.1 31.8 33.3 11.4 16.4 43.8 9.9 24.9 10.3 20.6 16.6 40.5 16.4 11.6 30.3 24.7 31.8 18.4 18.1 13.0 17.6 17.8 36.0 13.3 22.6 56.6 9.5 18.4 11.7 23.1 46.8 15.1 19.8 15.7 0.0 0.4 0.2 1.2 0.7 0.8 0.8 1.5 1.0 0.2 0.3 0.8 1.4 0.6 0.6 1.2 0.8 0.8 0.5 17.3 13.1 7.3 31.2 10.2 9.1 15.4 10.1 14.0 9.4 18.0 15.6 17.0 19.2 20.9 21.9 10.2 39.5 24.4 11.7 16.5 20.3 17.0 11.9 16.6 10.0 12.6 3.7 27.1 10.1 15.5 17.4 0.0 7.9 9.9 15.8 14.2 14.5 22.2 22.3 22.7 10.9 8.3 15.9 13.3 31.2 12.0 13.6 15.4 19.5 9.9 25.2 25.2 18.9 14.2 10.6 13.8 8.2 7.5 14.6 14.2 11.2 5.5 9.7 3.1 17.1 36.8 11.5 15.9 11.7 9.7 21.7 10.6 7.2 10.2 30.2 0.0 15.6 14.5 45.4 38.3 23.7 43.2 9.7 15.5 17.8 13.6 32.2 AFF1 "AF-4, AF4, MLLT2, PBM1" ENSG00000172493 "AF4/FMR2 family member 1" P51825 4 86935002-87141054 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 225.2;Microglial cells: 202.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069947 Approved Nucleoplasm,Mitochondria No No "Cluster 1: Neutrophils - Mixed function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Mitochondria" "HPA069947: AB_2686219" "unprognostic (1.01e-1)" "unprognostic (7.56e-2)" "unprognostic (2.57e-3)" "unprognostic (1.53e-1)" "unprognostic (1.33e-1)" "unprognostic (1.55e-2)" "unprognostic (1.79e-1)" "unprognostic (6.23e-2)" "unprognostic (6.09e-2)" "unprognostic (7.13e-2)" "unprognostic (1.24e-1)" "unprognostic (8.32e-3)" "unprognostic (5.86e-2)" "unprognostic (1.33e-2)" "unprognostic (4.41e-1)" "unprognostic (2.55e-1)" "unprognostic (2.71e-2)" 33.2 18.0 10.7 18.1 11.8 35.0 22.8 8.1 13.0 24.8 51.4 25.9 18.2 25.6 11.8 19.1 21.4 19.6 19.6 10.2 10.0 32.8 24.8 20.7 16.3 16.3 9.8 28.8 28.2 31.8 12.5 26.8 11.8 18.2 22.5 63.6 24.0 22.8 55.6 23.4 19.4 31.9 9.1 19.4 19.0 6.9 14.2 22.8 54.9 41.8 13.4 18.5 19.0 12.0 15.3 13.5 11.3 12.0 18.3 21.6 15.9 15.1 22.2 11.3 16.7 14.7 27.8 17.3 20.2 18.7 14.4 6.8 18.0 22.8 15.7 29.8 7.2 36.0 38.3 12.3 14.1 35.0 27.4 17.7 16.1 19.4 17.0 16.4 42.1 14.1 22.5 47.5 4.8 4.1 31.6 10.1 15.0 25.6 4.8 24.7 6.7 22.2 33.1 14.5 25.6 4.7 23.1 15.0 7.2 23.5 9.0 28.9 21.3 20.9 18.8 12.9 8.5 41.0 24.8 29.6 17.1 39.5 7.7 5.4 7.4 17.6 8.8 5.4 9.8 12.0 11.8 8.9 8.5 14.5 6.0 5.8 28.4 7.7 3.3 20.7 11.3 4.2 10.7 11.8 8.1 13.0 10.2 10.0 16.3 9.8 11.8 9.1 14.2 12.0 88.0 41.7 55.6 125.7 29.3 24.1 20.2 17.8 33.6 41.7 20.6 11.6 119.8 40.0 28.4 92.0 225.2 1.4 29.1 40.7 3.9 11.9 7.2 32.4 39.1 50.2 32.3 54.5 69.2 12.6 4.2 36.3 42.8 46.2 25.2 40.3 65.0 34.2 13.0 18.5 47.5 35.8 16.2 41.7 32.8 9.3 29.2 34.8 23.2 202.4 16.5 21.4 16.5 74.4 84.0 13.1 31.4 28.6 53.9 21.9 29.8 50.3 36.0 147.2 26.3 41.9 31.2 3.8 11.3 45.3 31.7 32.8 26.4 13.3 29.0 15.8 AFMID "DKFZp686F03259, KF" ENSG00000183077 Arylformamidase Q63HM1 17 78187317-78207701 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Tryptophan catabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 173.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 118.3;Proximal tubular cells: 105.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 6.4;intermediate monocyte: 16.7;memory B-cell: 5.4;myeloid DC: 7.6;non-classical monocyte: 11.0;plasmacytoid DC: 5.1" "Group enriched" "Detected in all" 5 "B-cells: 5.4;dendritic cells: 7.6;monocytes: 16.7" "Cell line enhanced" "Detected in all" "Hep G2: 186.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023861, HPA026536" Uncertain Approved Mitochondria NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA023861: AB_1844636, HPA026536: AB_1844637" "unprognostic (3.55e-2)" "unprognostic (1.54e-2)" "unprognostic (1.53e-1)" "unprognostic (2.65e-3)" "unprognostic (2.06e-1)" "unprognostic (4.73e-2)" "unprognostic (2.78e-1)" "unprognostic (1.83e-1)" "unprognostic (1.49e-3)" "unprognostic (1.53e-2)" "unprognostic (5.78e-2)" "unprognostic (9.59e-3)" "unprognostic (9.12e-2)" "unprognostic (1.80e-2)" "unprognostic (1.43e-1)" "unprognostic (1.94e-1)" "unprognostic (7.79e-2)" 14.6 7.6 52.8 11.7 76.1 10.8 65.5 67.3 66.2 15.2 35.5 15.8 17.9 15.3 13.9 18.7 22.9 19.0 22.5 52.6 60.5 88.8 173.2 27.1 12.0 74.4 71.3 31.9 59.3 9.1 9.1 26.7 66.8 28.3 18.8 4.0 38.7 18.4 19.2 32.9 15.5 13.4 56.6 14.6 22.1 13.2 68.6 8.9 15.0 14.4 13.4 13.2 19.0 114.8 21.3 29.4 25.4 23.3 27.9 32.5 13.7 29.8 16.8 20.4 24.5 31.5 17.2 65.8 19.2 22.8 11.9 17.8 43.5 26.0 28.5 41.9 34.6 53.2 35.2 186.5 24.4 44.4 26.2 43.8 26.9 23.9 31.0 33.5 38.8 19.6 54.7 22.4 16.0 20.9 34.0 67.2 20.9 51.1 49.8 38.3 25.9 79.2 27.9 19.3 56.2 41.5 25.5 75.5 24.4 25.1 22.8 42.3 19.3 31.2 20.5 19.9 21.4 33.8 24.2 68.0 25.7 21.5 8.2 1.7 6.4 0.8 0.7 16.7 1.2 5.4 1.1 1.2 7.6 2.1 0.6 0.6 1.8 1.9 11.0 5.1 1.1 1.8 52.8 76.1 67.3 66.2 52.6 60.5 74.4 71.3 66.8 56.6 68.6 114.8 17.9 16.0 16.0 0.7 9.7 26.4 19.8 11.5 79.6 1.2 44.7 34.3 13.2 58.6 12.1 64.4 4.2 12.9 2.1 15.1 17.6 11.5 0.2 21.3 14.5 16.7 13.1 11.3 7.7 8.5 11.2 18.6 23.9 23.8 2.5 9.5 17.9 118.3 10.1 1.7 4.0 26.8 10.2 20.9 20.7 2.7 22.4 21.9 30.2 6.5 8.8 1.6 2.1 3.0 74.2 7.8 27.6 21.8 25.4 15.7 17.8 105.8 14.7 1.7 0.0 15.2 18.1 1.5 13.3 52.1 41.1 11.5 4.3 21.6 30.6 14.5 AK2 ENSG00000004455 "Adenylate kinase 2" P54819 1 33007940-33080996 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Disease variant, SCID" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 440.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018479, CAB079913" Approved Approved Mitochondria NA NA 1100000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 32: U-937 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "CAB079913: AB_2546087, HPA018479: AB_1844676" "prognostic favorable (4.37e-4)" "unprognostic (3.25e-2)" "unprognostic (2.80e-2)" "prognostic unfavorable (8.65e-4)" "unprognostic (3.16e-2)" "unprognostic (8.21e-2)" "prognostic unfavorable (9.32e-4)" "unprognostic (7.86e-3)" "unprognostic (1.85e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (6.40e-4)" "unprognostic (4.95e-2)" "unprognostic (8.33e-3)" "unprognostic (9.56e-3)" "unprognostic (2.71e-1)" "unprognostic (1.40e-1)" "unprognostic (5.40e-3)" 85.3 88.6 39.9 76.9 45.0 74.3 80.4 44.1 49.0 79.6 49.8 117.2 140.0 58.6 52.1 108.5 65.3 49.0 114.1 38.8 43.8 181.6 172.9 59.3 73.3 48.5 42.8 59.9 78.9 123.6 49.4 68.4 50.4 63.2 114.0 51.0 81.1 55.5 154.2 74.4 139.4 68.1 44.0 57.2 92.7 54.8 44.3 85.9 86.6 122.9 113.4 84.2 76.9 49.3 339.1 153.4 131.6 149.7 94.9 116.6 132.8 185.0 143.5 267.7 280.2 283.2 311.9 602.1 218.4 139.8 204.2 235.4 312.5 327.0 276.6 261.6 229.3 396.2 270.0 219.9 218.2 712.5 222.2 118.1 238.2 232.7 471.2 163.3 190.2 245.7 436.9 230.4 165.0 174.2 273.0 392.8 181.2 337.4 222.4 314.7 222.2 415.6 286.2 205.1 190.8 114.8 205.4 235.0 584.8 151.4 194.5 517.2 138.9 165.5 194.3 259.4 357.5 238.0 324.7 565.7 232.4 664.6 195.5 49.2 158.8 198.0 77.1 145.5 81.8 122.3 72.7 74.0 195.8 105.8 72.9 67.9 42.1 115.3 130.4 154.2 96.8 188.1 39.9 45.0 44.1 49.0 38.8 43.8 48.5 42.8 50.4 44.0 44.3 49.3 60.5 51.3 79.0 19.6 44.0 125.2 101.4 228.1 63.7 21.1 66.5 72.6 106.9 71.4 142.8 112.2 83.4 158.0 37.0 109.6 256.3 120.2 108.3 50.0 42.1 70.7 50.4 50.9 16.2 123.7 164.6 58.0 66.3 47.0 40.0 38.8 41.4 135.5 96.1 8.4 19.7 84.7 89.5 44.8 60.1 42.8 46.9 48.4 87.2 12.2 67.3 22.1 48.4 14.1 22.0 110.5 67.2 44.0 55.7 109.0 236.9 440.0 67.0 41.8 52.6 34.1 108.4 91.0 31.6 88.6 122.7 216.6 40.7 72.2 122.6 120.5 AL021546.1 ENSG00000111780 "Novel protein" 12 120438198-120460006 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "CACO-2: 8.9;HEK 293: 11.5;U-266/84: 10.4" HPA062394 Uncertain Approved Mitochondria NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 11: Alveolar cells - Smell perception" Mitochondria "HPA062394: AB_2684749" "unprognostic (3.79e-2)" "unprognostic (1.74e-1)" "unprognostic (2.79e-1)" "unprognostic (2.90e-1)" "unprognostic (1.71e-1)" "unprognostic (1.33e-1)" "unprognostic (9.54e-4)" "unprognostic (2.04e-1)" 0.0 0.1 0.1 0.0 0.3 0.1 0.0 0.2 0.4 0.1 0.0 0.9 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.2 0.3 0.1 0.0 0.0 0.0 0.4 0.3 0.4 0.4 0.1 0.0 0.1 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.4 0.2 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.0 0.4 2.0 2.6 0.0 0.6 0.0 0.0 0.0 1.8 0.3 0.5 0.0 8.9 0.0 0.5 3.2 0.0 0.8 0.9 0.0 0.5 0.0 1.6 11.5 0.7 0.0 0.0 0.0 4.1 1.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.9 0.2 0.0 0.0 3.2 0.4 0.2 0.0 4.6 1.8 1.2 1.0 0.0 0.0 4.5 0.3 2.9 0.7 0.0 0.0 0.8 0.4 2.4 1.5 0.4 0.0 1.2 0.9 10.4 3.8 0.6 1.3 0.0 1.6 6.1 5.6 5.0 8.9 5.6 4.9 3.0 5.7 11.0 3.8 3.3 3.1 1.3 2.2 6.9 7.9 5.4 4.2 0.1 0.3 0.2 0.4 0.2 0.3 0.4 0.3 0.4 0.2 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AL139260.3 ENSG00000274944 "Novel protein" 1 38864501-38881617 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "testis: 5.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.7;Endometrial ciliated cells: 1.3;Glandular and luminal cells: 2.1;Respiratory ciliated cells: 4.4" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 3.1" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "HPA041188, HPA078331" Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 71: Testis - DNA repair" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" Nucleoplasm Mitochondria "HPA041188: AB_10794405, HPA078331: AB_2686882" "unprognostic (8.00e-2)" "unprognostic (3.86e-2)" "unprognostic (2.54e-1)" "unprognostic (2.00e-1)" "unprognostic (9.72e-3)" "unprognostic (4.27e-4)" "unprognostic (4.64e-7)" "unprognostic (2.59e-2)" "unprognostic (4.01e-2)" "unprognostic (1.22e-1)" "unprognostic (6.52e-2)" "unprognostic (9.54e-3)" "unprognostic (6.09e-6)" "unprognostic (1.30e-2)" "unprognostic (3.69e-1)" "unprognostic (1.27e-1)" "unprognostic (2.32e-3)" 1.4 2.0 0.0 0.9 0.0 0.4 0.4 0.0 0.9 0.5 0.0 2.7 1.7 0.3 0.0 2.7 0.7 0.2 0.4 0.0 0.0 1.1 1.8 0.4 2.5 0.0 0.0 0.4 0.5 0.0 0.9 0.6 0.0 0.7 1.6 0.0 2.4 0.0 0.3 1.5 1.2 0.0 0.0 1.2 1.6 5.1 0.0 0.4 0.6 0.0 0.5 0.9 1.0 0.0 16.7 1.3 3.7 0.0 0.3 0.0 1.6 0.0 0.0 0.0 0.0 8.0 17.5 2.8 14.5 0.0 0.3 11.1 0.0 0.0 0.0 9.2 2.3 1.4 2.7 2.2 0.0 19.3 5.4 0.0 0.0 0.8 0.5 1.2 0.9 0.0 6.4 4.7 1.1 4.1 8.7 20.6 7.7 8.5 9.8 9.8 7.7 17.9 0.0 8.6 7.0 3.6 9.2 7.5 2.1 3.1 5.0 6.1 6.8 2.2 7.6 7.7 16.0 1.8 17.3 12.9 8.2 7.5 2.2 0.0 0.4 0.0 0.0 0.5 0.2 1.2 0.0 0.1 1.7 1.3 0.1 0.0 0.9 0.0 1.4 3.1 0.7 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 ALKBH3 DEPC-1 ENSG00000166199 "AlkB homolog 3, alpha-ketoglutarate dependent dioxygenase" Q96Q83 11 43880811-43920274 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 90.9;Late spermatids: 103.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA009674, HPA046489" Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 34: Spermatids - Unknown function" Nucleoplasm Mitochondria "HPA009674: AB_1850460, HPA046489: AB_2679671" "unprognostic (3.53e-1)" "unprognostic (2.41e-1)" "unprognostic (7.43e-3)" "unprognostic (4.70e-2)" "unprognostic (6.94e-3)" "unprognostic (1.89e-1)" "unprognostic (7.71e-2)" "unprognostic (5.42e-2)" "unprognostic (8.56e-2)" "unprognostic (4.62e-1)" "unprognostic (5.87e-2)" "unprognostic (7.02e-2)" "unprognostic (2.09e-2)" "unprognostic (1.22e-1)" "unprognostic (2.31e-1)" "unprognostic (2.76e-1)" "unprognostic (1.35e-2)" 20.6 15.7 14.6 9.1 16.0 7.9 20.6 18.3 20.9 21.3 15.7 18.3 10.9 20.5 24.7 18.5 19.5 9.2 15.3 15.3 15.4 16.7 18.5 13.2 13.8 15.5 15.2 22.9 23.6 16.9 18.2 7.3 15.3 21.9 12.8 17.0 19.3 13.5 35.2 23.4 15.9 13.6 15.3 19.6 20.0 20.4 15.2 15.9 15.3 25.8 14.6 19.2 19.9 17.6 15.8 26.0 10.7 0.0 20.3 26.1 0.0 19.5 42.0 36.9 34.7 10.7 12.0 2.6 12.2 28.7 20.5 21.3 14.6 32.3 33.1 0.0 49.6 23.7 17.1 27.4 51.9 44.5 30.5 27.8 55.7 17.0 81.4 15.2 26.5 44.7 33.9 25.9 18.3 18.4 38.6 21.9 20.6 16.2 38.5 11.6 23.8 30.3 21.3 23.2 20.3 16.1 15.7 22.6 37.1 9.7 32.9 26.3 20.6 21.6 12.5 35.7 28.0 23.1 25.1 26.3 31.3 18.3 17.6 34.4 16.4 9.4 19.8 18.4 19.3 18.6 20.9 18.2 23.5 21.8 24.8 22.9 2.9 24.6 29.4 20.9 21.3 17.4 14.6 16.0 18.3 20.9 15.3 15.4 15.5 15.2 15.3 15.3 15.2 17.6 12.0 16.0 10.9 15.0 12.6 10.3 8.8 16.5 10.8 11.5 10.9 12.8 6.8 14.3 13.3 16.5 4.2 3.4 13.7 9.8 31.3 24.6 90.9 6.3 7.3 14.6 9.5 9.9 15.8 32.6 4.6 14.0 10.2 4.8 7.6 12.5 13.2 12.9 19.0 10.1 15.8 11.3 6.1 11.2 7.0 103.3 16.1 13.1 17.8 3.7 14.1 20.4 22.6 13.0 16.1 27.7 8.6 10.5 12.4 9.3 15.5 17.1 14.0 13.0 6.6 9.9 15.3 29.3 12.6 20.6 7.1 2.2 12.7 15.7 12.5 8.3 AMBRA1 "DCAF3, FLJ20294, KIAA1736, WDR94" ENSG00000110497 "Autophagy and beclin 1 regulator 1" Q9C0C7 11 46396414-46594125 "Predicted intracellular proteins" "Autophagy, Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Astrocytes: 65.6;Excitatory neurons: 101.4;Inhibitory neurons: 101.9;Microglial cells: 84.3;Oligodendrocyte precursor cells: 84.9;Oligodendrocytes: 136.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 11.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017825, HPA038535" Approved Approved Vesicles,Mitochondria NA NA "Cluster 38: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles Mitochondria "CAB017825: , HPA038535: AB_2676068" "unprognostic (1.76e-3)" "unprognostic (1.51e-1)" "unprognostic (1.95e-1)" "unprognostic (1.56e-1)" "unprognostic (6.00e-2)" "unprognostic (1.87e-1)" "unprognostic (1.46e-3)" "unprognostic (7.78e-2)" "unprognostic (1.32e-1)" "unprognostic (1.98e-2)" "unprognostic (5.53e-3)" "unprognostic (2.32e-1)" "prognostic favorable (1.61e-4)" "unprognostic (2.90e-1)" "unprognostic (8.17e-2)" "unprognostic (1.61e-2)" "unprognostic (7.98e-2)" 10.2 16.4 7.5 6.7 9.1 11.6 10.5 7.8 9.1 10.4 7.4 10.1 10.0 11.7 5.8 10.6 10.1 6.4 8.4 7.9 6.4 8.2 9.1 8.6 8.2 6.6 6.1 11.6 8.3 12.3 9.2 7.6 7.3 9.8 7.0 7.8 10.6 7.6 13.0 17.4 9.8 8.8 5.4 10.3 9.7 12.6 8.4 13.5 9.4 8.3 8.1 9.4 10.0 10.8 8.7 23.0 15.5 16.8 16.1 12.0 9.6 8.5 16.1 13.6 14.1 17.4 14.8 17.5 8.5 15.1 16.1 15.4 7.9 15.0 10.0 15.3 25.5 11.9 14.6 22.5 10.5 17.3 14.6 16.7 11.6 8.6 16.3 14.8 14.3 14.9 20.8 11.7 10.2 21.4 22.2 12.2 26.1 19.6 12.4 21.5 21.3 9.7 13.1 15.4 12.5 13.9 14.7 16.6 15.6 10.1 17.2 11.6 15.2 12.5 11.1 14.6 12.8 13.2 11.3 18.1 11.1 9.6 11.3 11.8 2.2 1.7 2.6 1.1 2.2 2.4 1.9 2.0 2.0 2.1 1.9 1.7 2.5 1.4 1.9 2.1 3.2 1.9 7.5 9.1 7.8 9.1 7.9 6.4 6.6 6.1 7.3 5.4 8.4 10.8 5.1 3.2 5.6 65.6 7.2 4.1 2.5 3.4 4.0 6.6 5.1 5.2 8.2 4.3 4.3 0.0 2.1 4.0 5.9 16.0 0.0 6.9 13.8 5.2 5.3 4.7 9.6 10.3 101.4 9.3 2.1 6.7 13.7 8.3 4.5 8.8 3.6 4.1 5.2 5.0 101.9 9.7 2.0 3.5 2.3 6.7 5.3 4.8 5.4 84.3 3.1 3.2 6.2 84.9 136.4 8.4 7.5 7.9 6.6 3.5 8.2 3.2 4.4 5.7 13.1 4.2 5.8 2.1 2.1 7.4 4.5 6.8 6.4 7.9 6.4 4.2 ANAPC13 "APC13, DKFZP566D193, SWM1" ENSG00000129055 "Anaphase promoting complex subunit 13" Q9BS18 3 134477706-134486716 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 463.7;Proximal tubular cells: 373.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046114 Uncertain Approved Mitochondria,Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 7: Kidney - Transmembrane transport" "Cluster 18: U-2197 - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Mitochondria, Cytosol" "HPA046114: AB_10961429" "unprognostic (2.84e-2)" "prognostic favorable (1.66e-4)" "unprognostic (2.98e-1)" "unprognostic (7.67e-2)" "unprognostic (1.65e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (1.67e-4)" "unprognostic (3.57e-1)" "unprognostic (2.90e-1)" "unprognostic (2.28e-3)" "unprognostic (6.44e-2)" "unprognostic (4.36e-1)" "prognostic favorable (2.66e-7)" "unprognostic (3.10e-1)" "unprognostic (9.90e-2)" "unprognostic (2.39e-1)" "unprognostic (1.16e-1)" 56.7 73.3 54.1 29.0 56.1 30.0 65.9 58.0 68.6 49.1 74.4 44.6 35.2 46.8 114.4 35.1 48.2 48.0 98.5 56.8 63.4 121.2 86.8 45.4 38.8 60.3 58.6 52.2 50.1 77.2 63.7 51.1 62.3 60.0 45.8 62.6 53.7 54.4 87.1 38.1 33.8 48.1 58.0 40.1 54.3 29.3 57.2 35.7 95.6 67.9 36.6 51.3 33.3 58.3 91.9 56.2 87.4 74.9 144.7 191.6 67.5 116.0 106.4 83.4 77.9 70.6 52.9 61.9 244.8 172.2 100.1 53.0 82.6 83.6 119.9 31.7 37.7 63.3 43.2 119.3 104.6 104.2 43.5 127.7 90.3 83.5 155.1 93.4 130.9 59.3 85.9 51.2 266.9 117.3 53.5 103.1 59.8 157.7 54.5 42.6 68.5 113.7 165.3 56.0 35.4 58.0 103.2 37.8 107.4 92.8 94.2 101.6 91.9 115.2 47.0 164.1 52.2 56.2 65.6 127.3 71.4 57.4 100.9 112.9 96.6 86.5 52.7 108.2 69.7 86.1 78.7 69.9 91.8 68.9 94.2 80.7 236.4 67.6 111.4 70.1 72.9 84.8 54.1 56.1 58.0 68.6 56.8 63.4 60.3 58.6 62.3 58.0 57.2 58.3 46.6 35.3 47.0 3.6 41.7 42.1 47.6 72.2 47.8 41.0 60.8 49.9 112.8 67.2 41.7 84.6 12.5 95.8 26.8 22.1 463.7 51.5 42.5 38.1 39.5 51.8 40.8 26.3 7.0 53.8 96.6 57.2 38.2 28.9 18.9 34.5 53.6 64.5 78.7 20.2 8.3 40.6 77.3 71.3 48.8 104.6 50.7 43.8 97.8 6.5 33.4 85.0 42.2 4.0 6.3 39.5 42.6 44.0 46.0 74.7 54.6 373.4 49.3 38.3 19.7 26.6 58.5 46.2 64.2 44.3 50.6 70.3 35.4 59.5 35.4 52.9 ANGEL2 "Ccr4d, FLJ12793, KIAA0759L" ENSG00000174606 "Angel homolog 2" Q5VTE6 1 212992182-213015867 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030795, HPA030796" Uncertain Approved "Nucleoplasm,Nuclear bodies,Mitochondria" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Nuclear bodies, Mitochondria" "HPA030795: , HPA030796: AB_10600979" "unprognostic (1.26e-1)" "unprognostic (2.02e-1)" "unprognostic (8.73e-2)" "unprognostic (2.76e-1)" "unprognostic (2.04e-2)" "unprognostic (1.93e-2)" "unprognostic (1.50e-1)" "unprognostic (4.98e-2)" "unprognostic (1.33e-2)" "unprognostic (2.92e-1)" "unprognostic (2.70e-3)" "unprognostic (6.46e-2)" "prognostic unfavorable (8.39e-6)" "unprognostic (9.62e-2)" "unprognostic (1.10e-1)" "unprognostic (1.44e-1)" "prognostic favorable (1.20e-4)" 7.5 6.6 13.1 6.9 14.9 6.4 10.4 11.1 14.7 7.9 9.2 6.6 5.2 8.6 8.1 5.9 7.4 6.1 5.8 12.8 11.1 7.7 8.0 6.6 10.5 10.6 10.8 10.8 6.7 7.8 6.2 6.5 10.1 8.2 6.4 9.2 6.0 6.2 7.3 9.1 7.2 7.1 10.1 9.8 6.3 5.5 13.1 10.2 8.1 7.1 9.2 7.1 6.3 11.6 12.2 9.6 15.2 13.2 11.5 16.8 13.6 9.8 16.3 15.4 15.3 6.3 8.9 11.8 8.8 9.7 8.5 9.4 17.8 9.4 15.5 22.3 10.6 11.9 7.4 6.3 12.5 11.8 13.6 10.4 11.9 12.1 12.2 13.1 13.2 10.4 13.9 11.8 18.0 4.0 13.6 7.9 36.4 6.6 6.8 6.9 27.4 12.4 12.1 8.2 7.5 21.7 11.9 15.7 18.3 16.2 12.2 8.6 9.8 12.7 6.7 15.7 15.1 8.6 8.9 7.9 14.2 8.7 11.9 6.6 4.4 5.9 5.1 4.3 6.5 5.7 6.4 5.4 5.5 3.5 6.7 5.7 2.7 10.9 3.5 3.3 8.9 5.2 13.1 14.9 11.1 14.7 12.8 11.1 10.6 10.8 10.1 10.1 13.1 11.6 23.1 48.1 9.8 26.8 23.8 6.9 8.5 11.7 12.5 21.2 14.6 10.2 15.2 17.2 14.5 12.9 10.4 14.8 26.2 7.6 11.7 10.3 1.5 11.3 19.8 15.9 6.7 18.1 33.2 10.5 15.0 18.0 14.3 11.7 17.1 28.8 16.1 12.5 11.8 28.6 26.3 8.4 14.2 20.4 10.5 2.6 15.5 17.1 3.6 30.0 17.3 11.6 16.5 30.2 49.3 10.2 6.4 13.9 24.2 10.8 10.7 16.9 22.5 17.8 19.7 21.7 16.1 9.5 16.6 12.7 7.0 10.9 25.8 17.9 8.0 7.4 ANKRD13D ENSG00000172932 "Ankyrin repeat domain 13D" Q6ZTN6 11 67289300-67302485 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "NB-4: 63.9;SK-MEL-30: 57.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039950 Approved Approved Nucleoplasm,Mitochondria No No "Cluster 10: Basophils - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Mitochondria "HPA039950: AB_10796337" "unprognostic (1.10e-1)" "unprognostic (1.18e-3)" "unprognostic (1.37e-3)" "unprognostic (4.19e-2)" "unprognostic (9.83e-3)" "unprognostic (1.58e-1)" "unprognostic (4.87e-3)" "unprognostic (3.72e-2)" "unprognostic (1.44e-1)" "unprognostic (1.16e-2)" "unprognostic (5.06e-3)" "unprognostic (3.71e-2)" "prognostic unfavorable (5.73e-10)" "unprognostic (1.62e-1)" "unprognostic (1.80e-1)" "unprognostic (4.01e-2)" "unprognostic (6.74e-2)" 12.0 14.7 13.3 6.8 14.3 0.3 11.4 10.9 20.7 19.5 10.8 13.8 3.1 12.5 2.9 24.4 15.3 7.9 12.0 16.5 12.9 16.2 8.9 13.8 15.0 13.8 11.7 14.1 9.5 6.0 28.9 5.2 15.1 23.8 2.3 2.0 14.4 7.3 3.7 15.0 13.8 6.5 10.2 39.2 12.8 12.1 15.8 10.0 11.2 3.8 5.7 17.5 20.5 19.6 9.7 7.2 5.8 12.3 10.9 10.1 3.8 7.0 8.4 7.2 5.6 6.4 10.1 11.6 12.4 5.6 10.7 12.4 4.5 8.6 1.0 19.9 5.3 11.6 11.3 4.3 16.8 14.0 27.8 10.4 11.8 6.2 6.8 14.1 9.5 9.2 6.3 12.4 8.0 14.1 18.0 63.9 2.5 19.8 10.1 28.5 4.9 9.9 13.6 6.0 6.0 9.8 7.0 16.7 57.0 4.5 14.3 33.1 7.7 7.1 6.1 7.9 8.2 9.8 9.4 5.6 17.4 21.4 8.2 6.6 0.6 5.7 2.0 2.1 1.3 0.8 1.5 2.8 1.2 0.5 0.5 3.2 1.9 3.1 1.4 1.8 1.6 1.2 13.3 14.3 10.9 20.7 16.5 12.9 13.8 11.7 15.1 10.2 15.8 19.6 23.2 0.0 18.8 18.9 22.2 14.1 11.7 15.4 17.6 61.1 21.5 20.8 7.0 8.6 14.5 16.5 75.0 8.3 73.6 7.5 1.9 8.3 18.0 27.7 19.7 17.9 10.8 8.2 29.8 6.9 9.0 15.7 20.4 18.0 25.3 25.7 22.1 3.0 20.0 42.1 29.7 7.9 18.3 52.0 21.4 6.0 22.1 45.8 12.4 18.7 49.7 20.8 49.4 17.6 18.4 9.9 4.6 17.0 30.7 19.9 2.3 2.6 30.4 51.7 13.1 13.6 18.5 3.1 8.1 19.3 25.1 7.5 49.9 28.9 8.4 19.8 ANKRD33B ENSG00000164236 "Ankyrin repeat domain 33B" A6NCL7 5 10564070-10657816 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.5;retina: 50.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 350.3;Excitatory neurons: 110.4;Rod photoreceptor cells: 73.4" "Cancer enhanced" "Detected in many" "renal cancer: 7.4" "Region enhanced" "Detected in many" "hippocampal formation: 20.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 23.7;HDLM-2: 47.0;HMC-1: 29.8" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "amygdala: 7.7;basal ganglia: 16.2;cerebral cortex: 19.6;hippocampal formation: 16.0;olfactory bulb: 10.0" HPA056974 Uncertain Approved Mitochondria NA NA "Cluster 58: Brain - Synaptic function" "Cluster 44: HDLM-2 - Immune response" "Cluster 9: Photoreceptor cells - Phototransduction" Mitochondria "HPA056974: AB_2683295" "unprognostic (6.19e-2)" "unprognostic (2.61e-1)" "unprognostic (1.09e-2)" "unprognostic (5.65e-3)" "unprognostic (2.84e-2)" "unprognostic (1.21e-1)" "unprognostic (1.99e-1)" "unprognostic (4.50e-3)" "unprognostic (4.41e-1)" "unprognostic (2.42e-3)" "unprognostic (1.14e-1)" "unprognostic (1.00e-1)" "prognostic favorable (4.16e-5)" "unprognostic (1.17e-1)" "unprognostic (4.80e-2)" "unprognostic (2.39e-2)" "unprognostic (5.47e-2)" 2.7 0.1 5.0 2.2 6.3 9.1 1.7 0.0 12.9 2.2 0.1 2.1 0.4 4.9 0.5 1.9 3.4 0.9 4.3 20.5 0.0 5.9 0.4 1.7 3.5 0.0 0.1 0.4 1.5 0.3 0.5 2.1 0.0 1.8 1.0 50.8 0.8 2.4 4.4 6.9 2.4 3.8 0.0 7.2 1.7 1.0 0.5 7.0 0.4 8.4 4.4 3.0 3.2 4.3 4.3 6.3 0.4 0.5 14.3 6.7 18.5 1.2 2.1 2.5 2.9 7.8 3.4 23.7 20.7 4.0 3.0 4.3 2.1 2.1 2.8 47.0 1.4 9.3 5.7 0.0 6.5 7.1 29.8 3.3 1.6 1.3 8.3 0.6 3.1 1.7 2.1 11.1 0.6 0.0 0.3 8.6 4.9 0.0 1.9 1.9 4.7 0.8 8.3 3.0 0.1 0.2 0.1 0.4 0.7 15.5 0.0 8.8 9.0 1.4 9.0 7.5 2.3 12.9 15.3 2.0 0.4 11.3 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 6.3 0.0 12.9 20.5 0.0 0.0 0.1 0.0 0.0 0.5 4.3 1.6 12.8 1.5 9.8 14.4 0.4 2.5 0.0 2.2 26.5 0.6 0.4 5.6 4.3 0.6 3.7 350.3 1.6 0.7 0.0 1.9 1.7 6.5 14.2 20.7 2.4 0.0 2.1 110.4 0.2 0.8 8.6 0.5 24.2 0.0 0.0 3.3 0.0 0.2 6.7 24.5 0.0 0.0 0.0 0.8 0.6 1.5 4.3 1.8 6.5 15.4 10.2 0.0 5.5 1.5 0.2 0.0 0.0 30.8 7.3 0.0 18.4 0.0 73.4 0.0 7.8 6.0 0.1 3.3 6.3 1.1 0.5 2.9 2.8 0.0 2.0 ANKRD34B DP58 ENSG00000189127 "Ankyrin repeat domain 34B" A5PLL1 5 80556755-80570280 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "brain: 40.7" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.0;Collecting duct cells: 3.7;Enteroendocrine cells: 1.8;Inhibitory neurons: 6.0;Kupffer cells: 1.2" "Cancer enhanced" "Detected in some" "prostate cancer: 2.3" "Region enhanced" "Detected in many" "thalamus: 40.7" "Immune cell enriched" "Detected in single" 5 "neutrophil: 3.8" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.8" "Cell line enriched" "Detected in some" 29 "RPTEC TERT1: 97.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA043327 Uncertain Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Mitochondria" Cytosol "HPA043327: AB_10794180" "unprognostic (1.05e-1)" "unprognostic (4.16e-6)" "unprognostic (2.07e-4)" "unprognostic (1.05e-1)" "unprognostic (3.03e-1)" "unprognostic (8.25e-4)" "unprognostic (6.44e-2)" "unprognostic (1.80e-1)" "unprognostic (9.41e-2)" "unprognostic (6.52e-3)" "unprognostic (1.93e-1)" "unprognostic (4.28e-2)" "unprognostic (1.02e-1)" "unprognostic (2.33e-1)" "unprognostic (2.94e-2)" 0.0 0.0 2.8 0.4 15.8 1.7 0.0 3.4 3.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 7.4 0.7 0.0 0.1 0.9 4.0 2.4 0.0 0.0 0.1 0.1 0.0 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.7 0.0 0.2 40.7 0.0 0.0 0.0 1.3 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 1.2 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.2 97.9 0.1 0.3 0.4 0.0 0.3 0.0 0.1 3.3 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.1 2.8 15.8 3.4 3.6 1.1 7.4 4.0 2.4 2.0 1.6 40.7 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.1 2.0 0.0 0.1 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.0 0.1 1.8 0.0 0.6 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.8 0.0 6.0 0.0 0.0 1.2 0.0 0.7 0.0 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 ANKRD34C ENSG00000235711 "Ankyrin repeat domain 34C" P0C6C1 15 79293285-79298235 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 7 "brain: 5.5" "Group enriched" "Detected in some" 4 "Excitatory neurons: 3.0;Inhibitory neurons: 1.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 17 "SCLC-21H: 8.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA045329 Approved Mitochondria NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Mitochondria "HPA045329: AB_2679291" "unprognostic (3.20e-1)" "unprognostic (1.08e-1)" "unprognostic (1.52e-2)" "unprognostic (1.81e-1)" "unprognostic (3.42e-3)" "unprognostic (5.31e-2)" "unprognostic (2.48e-1)" 0.1 0.1 1.4 0.0 0.5 0.0 0.0 2.0 1.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 3.0 0.0 0.0 0.1 0.0 2.2 2.8 0.0 0.2 0.0 0.7 0.0 3.4 0.0 0.0 0.5 0.0 0.0 0.1 0.7 0.0 0.0 0.2 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.5 2.0 1.9 0.4 3.0 2.2 2.8 3.4 0.2 5.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ANKRD37 Lrp2bp ENSG00000186352 "Ankyrin repeat domain 37" Q7Z713 4 185396021-185400628 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 93.7" "Cell type enhanced" "Detected in all" "Club cells: 257.6;Endometrial ciliated cells: 271.9;Respiratory ciliated cells: 263.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 23.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036626, HPA058127" Uncertain Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Cytosol" Mitochondria "HPA036626: AB_10671963, HPA058127: AB_2683614" "unprognostic (9.08e-2)" "unprognostic (2.85e-3)" "unprognostic (3.89e-2)" "unprognostic (2.36e-3)" "unprognostic (1.19e-1)" "unprognostic (2.27e-1)" "unprognostic (7.51e-2)" "unprognostic (9.12e-2)" "unprognostic (1.74e-1)" "unprognostic (1.09e-1)" "unprognostic (7.36e-2)" "unprognostic (9.69e-3)" "unprognostic (2.81e-2)" "unprognostic (1.38e-1)" "unprognostic (1.41e-1)" "unprognostic (6.45e-3)" "unprognostic (1.08e-1)" 16.9 10.3 30.7 4.3 31.7 3.3 13.4 32.2 58.7 36.6 45.2 11.2 7.8 6.1 3.7 69.5 11.7 6.7 27.4 31.5 31.9 14.3 26.2 9.9 4.1 33.7 32.9 29.1 17.5 1.4 21.8 15.1 32.1 35.2 9.5 93.7 31.2 5.7 30.2 14.9 6.4 4.4 33.9 7.1 9.0 11.2 34.7 5.1 23.9 13.3 7.5 10.8 29.6 32.4 12.6 1.6 1.1 5.4 7.4 4.5 4.9 4.8 3.7 3.7 6.8 2.9 3.4 4.3 2.4 8.4 6.4 4.3 6.5 6.2 4.2 12.4 0.7 2.8 5.8 8.3 3.3 2.4 7.6 1.2 6.4 3.0 3.6 23.8 3.9 2.9 5.0 8.2 9.4 2.6 2.6 12.1 1.7 1.1 8.3 0.5 1.5 13.4 4.5 1.1 7.2 12.9 3.7 4.1 14.4 4.6 4.1 2.3 5.1 6.6 5.0 4.2 5.1 13.3 5.2 2.2 20.9 2.8 6.9 0.5 3.3 8.3 4.1 3.2 3.9 6.8 3.6 6.7 2.0 6.9 2.4 3.4 1.2 3.9 3.3 3.4 4.5 2.5 30.7 31.7 32.2 58.7 31.5 31.9 33.7 32.9 32.1 33.9 34.7 32.4 39.3 22.4 28.7 9.1 104.2 59.4 41.8 197.9 42.7 29.9 66.9 92.3 1.8 11.5 257.6 9.2 29.2 25.0 69.8 93.8 25.4 25.2 6.2 271.9 18.9 44.7 119.9 8.4 8.0 23.3 43.0 28.6 142.2 96.5 61.7 7.7 12.1 25.8 15.4 10.1 7.9 186.6 89.5 8.1 170.2 3.2 9.3 53.3 142.3 12.2 17.7 99.8 1.0 4.0 4.6 32.3 53.3 11.7 223.5 38.5 60.9 31.5 263.3 115.2 6.6 27.3 38.7 32.1 28.4 54.0 48.2 84.4 65.8 7.4 50.8 20.2 ANKRD44 PP6-ARS-B ENSG00000065413 "Ankyrin repeat domain 44" Q8N8A2 2 196967017-197311173 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 36.5" "Cell type enhanced" "Detected in many" "B-cells: 153.3;Microglial cells: 390.7;NK-cells: 146.2;Oligodendrocyte precursor cells: 174.9;Oligodendrocytes: 199.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 46.4;HMC-1: 33.8;Karpas-707: 25.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030122, HPA056549" Approved Approved "Nuclear speckles,Mitochondria" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 57: B-cells - Immune response" Mitochondria "Nuclear speckles" "HPA030122: AB_10600980, HPA056549: AB_2683170" "unprognostic (3.64e-1)" "unprognostic (1.70e-2)" "unprognostic (1.05e-1)" "unprognostic (1.33e-1)" "unprognostic (2.63e-1)" "unprognostic (7.04e-5)" "unprognostic (1.97e-2)" "unprognostic (1.58e-3)" "unprognostic (2.27e-1)" "unprognostic (1.18e-1)" "unprognostic (8.25e-3)" "unprognostic (1.33e-1)" "unprognostic (1.33e-1)" "unprognostic (1.01e-1)" "unprognostic (1.29e-2)" "unprognostic (6.94e-2)" "unprognostic (3.67e-2)" 5.8 6.4 8.0 24.6 10.8 17.4 4.1 8.9 9.3 8.1 5.7 5.8 3.8 4.9 2.8 3.2 3.8 8.4 4.2 6.8 10.4 3.3 4.9 11.6 36.5 12.7 10.8 3.2 3.7 4.1 3.9 7.6 13.2 4.4 5.5 3.3 4.0 5.0 2.2 3.6 11.5 6.1 10.0 23.0 6.8 5.7 11.7 28.3 3.2 2.2 33.2 6.8 6.2 14.6 1.9 1.1 2.8 2.9 6.2 2.5 0.6 4.1 1.8 2.1 1.9 0.7 1.0 15.4 1.9 3.5 3.9 0.2 1.0 0.8 1.7 46.4 3.7 0.5 5.6 0.3 0.4 11.4 33.8 1.3 0.5 2.1 0.1 3.1 2.9 3.8 2.6 25.1 3.2 2.6 5.4 9.7 0.4 0.6 2.8 9.7 3.1 20.3 5.4 1.4 2.8 12.2 1.4 1.0 12.0 2.1 1.5 11.0 15.0 7.1 4.2 2.2 3.0 6.2 8.0 19.6 5.0 14.0 4.5 55.0 19.6 45.3 24.5 19.5 23.3 23.5 18.2 21.3 19.2 28.6 20.9 25.2 68.7 25.0 25.2 12.6 19.0 15.1 8.0 10.8 8.9 9.3 6.8 10.4 12.7 10.8 13.2 10.0 11.7 14.6 8.4 16.0 23.9 79.7 153.3 3.4 4.5 0.4 2.2 9.9 4.4 3.9 9.3 20.0 8.0 11.0 4.2 5.9 90.6 0.6 1.9 4.0 14.0 10.7 6.7 10.2 2.4 12.8 32.6 4.6 0.8 9.7 8.2 15.5 53.8 4.8 49.2 8.9 18.5 3.3 126.4 1.9 0.0 64.2 34.9 17.5 15.5 72.5 37.4 390.7 84.1 8.0 146.2 174.9 199.5 5.0 2.6 17.7 70.4 3.9 2.9 1.5 10.6 10.4 19.7 15.5 16.4 2.9 3.4 5.2 3.7 1.4 123.0 4.3 1.8 4.9 ANKRD52 "FLJ34236, PP6-ARS-C" ENSG00000139645 "Ankyrin repeat domain 52" Q8NB46 12 56237807-56258384 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043815 Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 34: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Mitochondria" "HPA043815: AB_10961762" "unprognostic (6.25e-3)" "unprognostic (6.45e-2)" "unprognostic (1.19e-1)" "unprognostic (2.67e-2)" "unprognostic (1.79e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (3.33e-4)" "unprognostic (9.84e-2)" "unprognostic (9.46e-2)" "unprognostic (5.43e-2)" "unprognostic (3.97e-3)" "unprognostic (1.24e-1)" "unprognostic (1.36e-1)" "unprognostic (1.61e-3)" "unprognostic (1.27e-1)" "unprognostic (3.70e-2)" "unprognostic (6.31e-2)" 8.4 21.5 10.9 9.8 11.3 9.6 8.7 9.3 12.9 11.9 4.9 12.3 8.4 12.4 5.7 10.5 11.0 6.1 12.9 9.6 13.3 11.6 7.9 9.4 9.2 17.7 16.2 12.9 12.9 19.8 13.2 7.1 21.4 11.2 8.1 9.6 10.9 7.9 25.0 11.2 12.8 11.0 9.2 10.9 10.5 7.4 15.4 8.8 11.2 17.0 9.6 12.0 9.8 10.3 24.7 58.5 25.9 47.4 20.7 16.2 18.2 48.1 20.9 42.1 18.9 39.0 13.4 26.1 29.9 47.3 14.8 31.5 29.0 21.0 24.2 25.3 29.1 46.9 38.6 15.0 14.3 37.3 26.2 16.7 23.2 39.0 19.7 30.9 24.8 21.1 19.6 13.8 40.1 34.2 30.0 12.3 10.9 16.1 27.4 23.4 17.8 10.4 27.7 30.0 19.6 17.8 52.2 33.1 18.9 19.9 26.5 14.3 34.4 43.4 38.1 24.7 30.4 12.7 18.0 12.4 45.0 12.2 29.0 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 10.9 11.3 9.3 12.9 9.6 13.3 17.7 16.2 21.4 9.2 15.4 10.3 4.1 6.4 5.3 9.1 7.8 11.2 3.6 8.4 10.2 5.0 9.1 6.9 6.7 4.3 4.3 12.9 27.1 5.8 7.9 12.6 0.0 10.4 0.5 5.8 9.7 5.7 9.6 5.5 12.8 9.5 7.4 5.4 8.2 9.0 1.3 8.6 6.8 6.5 7.0 8.4 12.5 6.6 20.3 7.1 7.5 1.1 6.2 4.8 10.6 7.5 4.6 3.4 7.2 7.5 8.4 15.7 7.0 4.9 8.7 5.7 9.2 6.4 4.2 6.0 0.0 5.6 7.6 6.4 8.8 10.0 10.9 3.7 6.0 5.5 8.9 4.4 ANKRD63 ENSG00000230778 "Ankyrin repeat domain 63" C9JTQ0 15 40281444-40282586 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 81 "brain: 20.9" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "basal ganglia: 20.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.9;THP-1: 1.4" "Region enhanced" "Detected in many" "basal ganglia: 56.7" HPA066743 Approved Mitochondria NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 43: Cardiomyocytes - Nuclear processes" Mitochondria "HPA066743: " "unprognostic (9.36e-2)" "unprognostic (7.45e-2)" "unprognostic (8.32e-2)" "unprognostic (4.42e-1)" 0.0 0.0 3.6 0.0 20.9 0.0 0.0 0.0 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 1.3 2.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.9 0.9 0.4 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.5 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 20.9 0.0 10.6 1.3 2.1 0.0 0.3 0.0 0.0 4.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AP001267.5 ENSG00000285827 "Novel protein" 11 118401602-118482737 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 7.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 16.0;Alveolar cells type 2: 24.1;Club cells: 14.9;granulocytes: 20.2;Respiratory ciliated cells: 13.8" "Region enhanced" "Detected in many" "cerebellum: 3.8" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA044629 Uncertain Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 2: Karpas-707 - Immune response" "Cluster 11: Alveolar cells - Smell perception" Mitochondria "HPA044629: AB_2679028" 1.2 1.2 0.7 1.5 0.9 7.2 1.3 3.8 1.3 0.8 0.4 1.3 1.8 0.8 1.1 0.6 0.8 0.7 1.2 0.7 1.4 1.2 1.2 0.9 2.4 0.2 0.1 0.8 0.8 1.6 0.7 0.2 1.4 1.2 1.5 1.4 0.8 1.5 0.5 1.8 0.8 0.0 1.0 1.4 0.7 0.2 2.6 1.1 1.8 1.3 1.0 1.6 3.1 0.7 2.0 2.7 0.9 0.8 3.8 1.5 1.2 1.9 1.9 3.3 2.5 2.6 3.6 1.9 4.0 2.4 2.8 2.4 2.8 4.0 1.8 4.3 1.2 1.6 1.8 2.9 3.0 1.4 1.3 2.3 3.0 1.2 2.4 6.1 3.4 6.7 1.7 2.4 4.5 5.7 1.7 5.5 2.6 3.9 2.2 3.4 3.4 1.2 3.3 2.3 2.4 1.2 1.5 3.0 1.9 1.5 1.3 2.0 4.2 1.1 1.9 1.7 1.6 5.2 0.7 3.1 1.0 5.5 5.1 6.0 4.9 4.2 4.1 6.1 4.4 4.0 5.0 5.1 4.2 4.0 4.1 3.7 4.0 7.2 5.8 10.6 0.7 0.9 3.8 1.3 0.7 1.4 0.2 0.1 0.2 0.0 0.2 1.6 0.0 16.0 24.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 20.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 APBB2 "FE65L, FE65L1, MGC35575" ENSG00000163697 "Amyloid beta precursor protein binding family B member 2" Q92870 4 40810027-41216714 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 72.9" "Group enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 586.1;Oligodendrocytes: 803.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 14 "naive B-cell: 5.6" "Lineage enriched" "Detected in single" 14 "B-cells: 5.6" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 138.7;TIME: 192.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023542 Approved Approved Mitochondria No No "Cluster 21: B-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA023542: AB_1844909" "unprognostic (4.43e-2)" "unprognostic (4.40e-2)" "unprognostic (2.04e-2)" "prognostic unfavorable (1.97e-4)" "unprognostic (5.91e-3)" "unprognostic (8.13e-2)" "unprognostic (5.77e-2)" "unprognostic (4.00e-3)" "unprognostic (2.51e-1)" "unprognostic (1.21e-2)" "unprognostic (1.61e-1)" "unprognostic (1.33e-1)" "unprognostic (2.19e-3)" "unprognostic (9.35e-3)" "unprognostic (3.92e-2)" "unprognostic (2.29e-2)" "unprognostic (2.61e-1)" 41.6 9.1 23.1 5.4 42.3 8.6 25.1 38.1 24.5 16.1 3.7 13.9 8.3 14.0 5.9 8.9 13.1 16.1 21.5 20.6 30.6 16.5 14.7 18.6 7.4 42.9 39.6 32.1 10.8 8.5 8.5 17.6 39.5 8.7 7.7 15.7 8.6 9.8 28.7 12.6 7.0 14.9 25.2 14.8 11.3 8.5 36.7 13.2 33.6 21.7 5.6 10.7 13.1 72.9 19.4 9.4 20.6 28.8 64.9 50.7 45.2 38.5 45.8 14.0 24.5 34.1 40.2 33.9 20.7 16.5 44.5 5.6 36.5 49.4 25.0 1.1 7.3 0.4 23.5 21.1 65.0 19.2 1.1 76.7 24.6 42.5 43.0 58.2 138.7 19.0 1.1 0.7 86.1 16.3 6.3 3.6 17.1 9.8 17.9 50.9 58.6 38.4 19.9 8.9 27.2 15.4 11.7 6.6 6.9 23.7 17.2 2.2 192.3 20.1 59.5 13.8 61.1 8.1 18.5 41.2 20.7 30.8 24.6 0.4 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 5.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 23.1 42.3 38.1 24.5 20.6 30.6 42.9 39.6 39.5 25.2 36.7 72.9 58.8 80.1 14.5 46.7 5.0 10.7 3.8 10.4 7.4 7.6 25.5 13.6 22.5 12.8 6.3 9.2 6.2 14.4 0.5 5.2 7.9 3.8 14.5 5.6 32.8 39.4 3.0 5.3 121.3 6.4 2.8 25.2 12.8 7.5 1.3 13.5 47.2 13.8 3.2 62.2 171.3 4.0 16.2 4.0 6.7 23.1 35.8 2.5 7.2 164.9 0.1 9.3 0.0 586.1 803.4 6.2 6.7 37.2 0.2 2.7 5.5 6.3 4.0 7.6 59.2 43.2 51.4 3.8 10.8 7.3 11.9 6.0 1.2 24.0 7.4 3.6 APOO "FAM121B, MGC4825, Mic23, MIC26, MICOS26, My025" ENSG00000184831 "Apolipoprotein O" Q9BUR5 X 23833353-23907938 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 180.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003187 Supported Approved Mitochondria,Cytosol "Secreted to blood" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Cytosol "HPA003187: AB_1079375" "unprognostic (2.53e-2)" "prognostic favorable (3.77e-4)" "unprognostic (4.86e-2)" "unprognostic (6.38e-3)" "unprognostic (3.45e-1)" "unprognostic (2.42e-1)" "unprognostic (6.18e-2)" "unprognostic (2.95e-1)" "unprognostic (6.45e-2)" "unprognostic (1.50e-2)" "unprognostic (1.06e-1)" "unprognostic (2.22e-1)" "prognostic favorable (2.56e-6)" "unprognostic (2.53e-2)" "unprognostic (5.21e-2)" "unprognostic (3.48e-1)" "unprognostic (5.88e-3)" 9.0 23.7 55.8 9.0 58.0 7.9 13.3 58.1 76.3 13.1 67.8 17.3 14.4 10.6 19.6 12.6 20.8 9.3 65.1 57.9 58.4 46.5 18.2 8.6 11.7 58.8 57.0 9.4 14.2 62.0 29.2 10.9 57.3 13.7 18.8 52.8 19.7 15.0 45.9 7.7 12.0 12.0 57.0 8.4 17.7 16.8 56.8 14.0 20.3 73.2 11.6 11.2 8.1 57.1 36.5 32.7 53.9 37.8 8.8 19.9 8.3 17.9 21.9 37.4 38.8 19.3 17.0 31.5 21.9 16.5 48.5 29.3 68.5 35.7 41.2 33.4 48.7 15.9 28.6 31.1 20.8 40.9 17.1 22.2 20.7 41.2 30.4 20.1 26.6 38.8 22.9 33.2 35.1 34.6 41.2 43.0 49.2 47.5 52.7 31.5 26.6 75.6 74.1 18.4 36.4 26.5 39.0 36.7 39.7 52.4 63.6 17.9 6.5 23.9 14.6 86.6 27.9 26.3 50.5 28.7 38.5 19.8 35.8 14.8 4.8 1.4 12.6 15.9 16.6 10.8 13.7 12.5 14.0 10.2 10.9 10.7 3.0 10.3 16.0 16.6 14.0 7.7 55.8 58.0 58.1 76.3 57.9 58.4 58.8 57.0 57.3 57.0 56.8 57.1 7.4 16.0 11.5 61.7 11.8 14.0 17.0 74.3 11.4 20.4 14.3 17.0 61.8 21.5 28.3 23.9 14.6 17.2 11.3 12.8 180.0 28.4 25.9 56.0 13.0 10.1 7.2 20.8 61.4 16.0 8.9 11.7 13.3 24.4 3.8 14.2 7.9 13.9 22.7 20.2 76.5 17.0 44.7 14.6 12.0 15.7 11.5 9.9 28.4 74.0 34.2 50.0 8.2 43.7 76.5 10.2 20.0 15.8 14.8 14.1 24.0 80.6 106.9 32.4 6.6 10.8 22.3 26.1 53.2 18.9 7.0 12.4 9.5 17.0 22.3 16.8 APOOL "AAIR8193, CXorf33, FAM121A, Mic27, MICOS27, UNQ8193" ENSG00000155008 "Apolipoprotein O like" Q6UXV4 X 85003877-85093316 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000612 Approved Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA000612: AB_1078594" "prognostic unfavorable (2.68e-5)" "unprognostic (2.72e-2)" "unprognostic (6.16e-2)" "unprognostic (5.71e-3)" "unprognostic (4.27e-3)" "unprognostic (1.47e-1)" "unprognostic (2.73e-1)" "unprognostic (2.22e-2)" "unprognostic (8.35e-2)" "unprognostic (1.10e-1)" "unprognostic (2.77e-1)" "unprognostic (8.20e-2)" "prognostic favorable (1.35e-12)" "unprognostic (2.67e-2)" "unprognostic (5.65e-2)" "unprognostic (7.11e-2)" "unprognostic (7.51e-2)" 5.9 6.5 2.8 3.7 3.2 3.7 6.6 3.6 5.2 4.3 5.4 5.9 5.9 4.4 4.7 6.2 5.1 4.0 11.5 4.2 3.9 11.2 14.5 4.3 3.3 4.5 4.3 4.1 6.0 11.6 3.2 4.1 4.6 5.9 6.5 6.8 5.8 4.4 17.8 6.7 4.6 5.9 2.9 3.5 6.8 2.2 4.6 3.6 8.3 17.9 3.5 4.2 4.0 4.3 11.4 6.5 6.0 8.2 16.9 11.7 6.4 7.4 6.9 6.2 6.0 7.0 6.3 8.3 6.9 8.4 11.7 8.8 18.3 7.0 9.3 8.4 8.0 8.8 10.2 7.2 11.0 17.5 9.1 11.8 11.8 10.4 18.4 7.2 8.8 10.7 15.2 10.7 10.8 6.1 7.2 7.1 4.9 6.8 12.1 7.9 14.6 8.6 7.8 8.3 0.6 9.8 14.1 12.7 8.8 6.4 7.7 8.3 9.2 8.5 8.3 17.5 8.6 6.9 24.4 7.1 10.9 12.4 7.3 2.4 2.0 0.6 1.9 2.8 1.7 2.1 1.7 1.4 2.1 1.9 2.1 2.0 0.4 1.2 2.5 2.6 1.0 1.0 2.8 3.2 3.6 5.2 4.2 3.9 4.5 4.3 4.6 2.9 4.6 4.3 16.7 16.0 19.1 25.8 10.7 5.6 13.3 5.3 6.2 26.7 16.8 11.9 45.4 15.7 7.7 20.2 14.6 15.3 9.3 10.6 13.7 18.1 0.2 17.0 15.4 13.0 37.1 14.9 32.3 14.0 11.3 13.9 17.3 17.4 21.5 18.3 15.0 51.6 12.0 21.9 26.2 15.3 4.1 15.2 2.3 0.8 13.7 11.4 0.0 21.5 9.5 13.6 8.2 30.2 36.2 17.5 14.6 15.4 8.7 19.6 15.6 43.7 7.6 16.8 19.7 19.3 16.9 3.1 8.2 11.5 3.4 19.4 6.6 16.8 15.4 17.8 AREG "AREGB, SDGF" ENSG00000109321 Amphiregulin P15514 4 74445136-74455005 "Cancer-related genes, Human disease related genes, Predicted membrane proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 129.9;placenta: 328.8;urinary bladder: 145.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1119.1;Basal prostatic cells: 1254.3;Macrophages: 1271.1;Paneth cells: 909.8;Urothelial cells: 2102.9" "Cancer enhanced" "Detected in all" "colorectal cancer: 67.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "basophil: 11.0;eosinophil: 11.8;NK-cell: 3.8" "Group enriched" "Detected in many" 10 "granulocytes: 11.8;NK-cells: 3.8" "Cell line enhanced" "Detected in many" "CACO-2: 379.0;HBEC3-KT: 648.1;hTCEpi: 644.0;hTERT-HME1: 1365.7;MCF7: 416.8" "Region enriched" "Detected in single" 4 "olfactory bulb: 1.2" "Low region specificity" "Detected in many" "HPA008720, CAB023519" Approved Approved Mitochondria NA NA 1520000 "Cluster 2: Granulocytes - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" Mitochondria "CAB023519: AB_2060673, HPA008720: AB_1844978" "unprognostic (1.44e-2)" "unprognostic (1.84e-3)" "unprognostic (3.36e-2)" "unprognostic (2.26e-1)" "unprognostic (3.54e-3)" "prognostic unfavorable (2.61e-5)" "unprognostic (1.02e-2)" "prognostic unfavorable (1.05e-5)" "unprognostic (2.90e-1)" "unprognostic (8.06e-2)" "prognostic unfavorable (8.32e-5)" "unprognostic (2.56e-2)" "unprognostic (2.49e-3)" "unprognostic (2.40e-2)" "unprognostic (1.69e-1)" "unprognostic (1.23e-1)" "unprognostic (6.83e-3)" 48.1 4.6 0.1 36.7 0.1 129.9 61.6 0.1 0.8 19.2 1.8 18.7 3.3 3.7 0.2 43.4 13.2 74.1 20.5 0.3 0.1 2.5 4.0 36.1 1.9 0.3 0.2 12.4 4.5 1.5 9.5 328.8 0.8 6.5 18.9 0.1 11.7 0.7 18.4 15.3 10.2 6.5 0.2 10.0 20.2 9.3 0.4 7.1 5.4 0.8 3.0 145.6 13.8 0.4 15.9 107.3 0.0 0.0 0.9 1.4 0.0 3.2 5.0 0.7 2.9 379.0 59.8 0.0 8.0 0.0 0.0 17.4 0.1 648.1 6.5 0.1 0.0 0.4 2.8 18.0 191.9 2.3 0.4 5.9 644.0 37.8 1365.7 0.9 0.2 0.4 1.6 0.7 14.4 416.8 0.2 0.0 0.0 78.6 42.8 0.0 0.1 0.1 36.4 2.9 0.5 0.2 22.2 1.2 0.0 0.4 11.6 0.1 1.0 0.0 15.3 5.3 0.1 0.9 0.0 0.1 0.0 0.0 1.7 11.0 0.0 11.8 0.0 0.0 0.0 0.2 0.4 0.0 0.8 0.3 0.2 0.0 0.1 3.8 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.8 0.3 0.1 0.3 0.2 0.8 0.2 0.4 0.4 670.0 198.7 301.9 0.0 190.7 1119.1 1254.3 73.0 303.9 0.0 801.5 460.2 49.0 62.9 183.9 51.5 0.0 1.8 836.1 878.0 0.0 61.8 70.4 167.7 12.3 32.2 41.6 18.5 0.0 10.2 1.5 80.8 254.9 193.1 680.5 0.9 10.8 4.2 32.2 0.0 0.5 393.5 8.2 250.4 196.4 12.1 0.3 1271.1 33.8 0.0 1.7 0.8 20.6 0.0 0.0 497.1 909.8 1.2 352.1 115.3 55.7 0.7 53.3 0.2 19.7 10.3 20.2 68.3 51.1 194.5 342.4 1.1 473.6 1.2 308.9 2102.9 ARHGAP20 KIAA1391 ENSG00000137727 "Rho GTPase activating protein 20" Q9P2F6 11 110577042-110713189 "Disease related genes, Predicted intracellular proteins" "GTPase activation" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 78.0;Excitatory neurons: 97.9;Inhibitory neurons: 159.9;Leydig cells: 48.7;Oligodendrocyte precursor cells: 90.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 24.6;ASC TERT1: 8.2;HHSteC: 5.5;SiHa: 7.2;U-2197: 4.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038458, HPA038459, HPA076303" Uncertain Approved Mitochondria NA NA "Cluster 71: Testis - DNA repair" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA038458: AB_10672517, HPA038459: AB_2676022, HPA076303: AB_2686792" "unprognostic (1.69e-2)" "unprognostic (3.97e-2)" "unprognostic (6.83e-2)" "unprognostic (1.34e-1)" "unprognostic (2.66e-1)" "unprognostic (8.47e-3)" "unprognostic (2.75e-1)" "unprognostic (2.90e-2)" "unprognostic (4.15e-2)" "unprognostic (5.70e-2)" "unprognostic (1.38e-1)" "unprognostic (9.52e-2)" "unprognostic (2.82e-5)" "unprognostic (1.84e-2)" "unprognostic (9.15e-2)" "unprognostic (6.21e-3)" "unprognostic (4.10e-2)" 8.9 2.3 3.8 1.3 4.1 0.0 4.5 1.8 3.5 4.4 0.3 1.9 0.8 4.4 3.6 2.2 3.1 2.2 0.4 3.5 2.5 0.3 1.7 4.1 1.2 0.5 0.7 1.2 0.2 0.8 0.9 1.7 0.5 3.9 2.8 1.1 1.3 8.8 0.9 1.0 1.5 3.3 1.2 1.3 1.8 8.3 2.0 0.4 4.8 1.3 0.8 3.2 2.2 0.8 0.0 0.0 0.0 0.0 24.6 8.2 0.0 1.1 3.3 0.4 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.2 0.1 0.3 0.0 5.5 0.0 0.0 3.0 0.0 0.0 0.0 0.1 2.4 0.2 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 2.1 0.3 7.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 4.4 0.0 0.1 0.0 2.1 0.9 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 4.1 1.8 3.5 3.5 2.5 0.5 0.7 0.5 1.2 2.0 0.8 1.7 0.0 2.3 5.2 1.7 0.8 4.9 1.1 10.2 9.9 0.5 6.0 0.9 1.5 2.5 0.0 0.0 0.1 0.0 0.0 0.0 0.2 13.1 1.7 78.0 4.3 0.0 0.0 97.9 0.4 0.1 15.1 0.0 1.2 1.3 1.1 9.7 2.0 0.2 3.3 159.9 0.2 0.0 0.8 1.6 4.6 48.7 2.1 3.6 22.5 0.0 0.7 0.0 90.0 3.2 0.7 0.0 36.5 1.2 1.9 0.0 0.0 0.0 1.4 0.0 2.3 4.6 11.8 11.7 1.6 0.4 0.7 0.5 3.6 0.0 0.8 ARL9 ENSG00000196503 "ADP ribosylation factor like GTPase 9" Q6T311 4 56505209-56524959 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 12.9" "Group enriched" "Detected in many" 17 "Early spermatids: 100.7;Late spermatids: 292.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HSkMC: 2.8;REH: 7.5;SCLC-21H: 7.0" "Region enhanced" "Detected in single" "cerebellum: 1.4" "Low region specificity" "Detected in all" HPA072942 Enhanced Approved Nucleoli,Mitochondria NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria Nucleoli "HPA072942: AB_2686561" "unprognostic (9.91e-2)" "unprognostic (2.19e-1)" "unprognostic (2.34e-2)" "unprognostic (2.69e-1)" "unprognostic (1.24e-3)" "unprognostic (6.86e-3)" "unprognostic (3.32e-2)" "unprognostic (1.47e-1)" "unprognostic (4.93e-2)" "unprognostic (4.46e-2)" "unprognostic (1.51e-1)" "unprognostic (1.71e-1)" "unprognostic (6.79e-6)" "unprognostic (1.47e-2)" "unprognostic (1.08e-1)" "unprognostic (1.99e-1)" "unprognostic (3.29e-2)" 0.2 1.1 1.2 0.2 1.3 2.2 0.8 1.4 1.6 1.5 4.2 1.2 0.3 1.4 0.4 0.5 0.5 1.0 0.2 1.1 1.4 0.2 0.1 0.2 0.2 2.2 1.4 1.4 0.1 0.1 1.2 0.0 1.3 1.0 0.2 0.4 0.8 1.6 0.2 2.1 0.5 1.7 1.0 0.1 0.4 12.9 1.5 0.4 0.4 0.0 0.2 0.6 1.9 1.3 0.0 0.1 0.3 0.2 0.6 1.7 0.0 0.6 0.3 1.3 1.2 0.1 0.5 0.3 0.0 1.0 0.0 0.0 0.1 0.0 0.6 0.0 0.1 0.1 0.0 0.0 1.7 0.0 0.3 2.8 0.4 1.2 0.1 0.4 1.3 0.0 0.0 0.3 1.1 0.0 0.1 0.0 1.6 0.0 0.8 7.5 0.0 0.0 0.0 0.0 7.0 0.0 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.2 0.0 1.2 1.3 1.4 1.6 1.1 1.4 2.2 1.4 1.3 1.0 1.5 1.3 0.4 0.0 1.1 0.3 0.0 6.0 1.3 3.6 1.8 0.1 2.6 2.5 0.1 1.5 0.3 1.8 0.0 0.1 0.1 0.0 0.0 0.6 100.7 2.5 2.0 0.7 0.0 0.0 3.3 0.2 0.1 3.0 0.0 2.9 0.0 2.0 0.4 0.0 0.1 0.0 2.4 0.8 0.0 0.8 0.3 292.4 1.5 0.2 5.4 0.0 0.0 0.9 0.0 3.0 1.7 0.8 0.1 1.2 0.0 1.6 0.1 0.7 0.4 0.1 0.0 1.3 0.9 11.5 1.2 0.0 1.6 0.0 0.2 1.6 0.6 0.3 ARMC1 "Arcp, FLJ10511" ENSG00000104442 "Armadillo repeat containing 1" Q9NVT9 8 65602458-65634217 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026085 Approved Approved Mitochondria NA NA "Cluster 34: Basophils - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA026085: AB_1845031" "prognostic unfavorable (4.81e-4)" "unprognostic (1.35e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (2.87e-4)" "unprognostic (8.18e-2)" "unprognostic (1.45e-2)" "prognostic unfavorable (7.73e-4)" "unprognostic (4.13e-2)" "unprognostic (7.49e-2)" "unprognostic (2.19e-2)" "prognostic unfavorable (9.15e-4)" "unprognostic (1.81e-1)" "unprognostic (3.30e-3)" "unprognostic (1.08e-1)" "unprognostic (1.07e-1)" "unprognostic (1.98e-1)" "unprognostic (1.66e-1)" 16.6 15.4 19.0 13.5 23.8 13.1 18.4 21.0 29.0 15.2 16.4 16.4 15.6 18.6 16.4 16.8 13.2 11.9 21.6 19.7 21.7 22.0 23.2 12.4 19.3 19.8 20.9 18.8 14.9 21.0 9.0 15.0 20.4 17.8 16.6 12.5 15.7 16.9 19.2 11.5 13.7 21.6 20.4 13.9 13.6 9.4 20.8 22.3 14.7 24.6 20.3 16.8 10.8 25.6 51.3 35.6 34.2 32.0 33.1 30.1 24.8 44.7 33.2 46.5 34.2 26.5 40.3 79.0 11.2 41.0 50.7 33.4 61.9 35.9 62.9 45.0 31.7 61.3 20.6 38.9 44.1 23.4 32.0 27.8 40.9 38.3 52.5 36.6 48.5 55.3 64.5 54.7 50.6 32.9 86.9 30.7 35.7 63.6 38.9 49.9 42.6 27.9 37.2 23.8 25.3 27.3 28.5 35.4 44.3 34.6 56.9 27.2 28.5 43.8 32.1 33.8 42.5 40.3 45.2 53.2 41.5 42.8 43.7 36.3 5.6 7.4 8.3 9.3 11.4 9.8 9.9 10.2 7.2 6.9 9.9 10.1 0.7 11.5 9.2 6.4 11.4 6.5 19.0 23.8 21.0 29.0 19.7 21.7 19.8 20.9 20.4 20.4 20.8 25.6 26.6 41.7 27.7 16.0 33.0 15.8 12.1 17.5 19.4 23.7 20.7 19.4 33.4 18.6 24.5 16.5 22.9 35.0 32.9 14.4 54.8 28.3 10.4 15.9 26.9 23.7 23.4 62.7 23.9 28.1 43.9 24.4 20.4 15.3 10.8 31.5 21.4 25.6 25.0 20.2 22.7 17.0 24.4 18.9 12.6 5.7 26.1 20.6 21.4 19.7 31.6 47.3 24.7 15.1 47.7 28.0 13.0 33.4 27.2 18.9 19.9 47.7 17.6 21.9 6.6 29.0 32.2 50.7 24.5 29.9 18.5 37.6 28.0 28.1 23.4 9.1 ARMCX2 "ALEX2, GASP9, KIAA0512" ENSG00000184867 "Armadillo repeat containing X-linked 2" Q7L311 X 101655281-101659850 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 154.8" "Cell type enhanced" "Detected in many" "Sertoli cells: 59.2" "Cancer enhanced" "Detected in all" "thyroid cancer: 47.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "LHCN-M2: 164.1;NTERA-2: 117.2;SuSa: 90.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005761 Enhanced Approved Nucleoplasm,Mitochondria Yes No "Cluster 21: B-cells - Adaptive immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria Nucleoplasm "HPA005761: AB_10600782" "unprognostic (1.33e-1)" "unprognostic (2.26e-2)" "unprognostic (4.25e-2)" "unprognostic (1.48e-1)" "unprognostic (9.59e-2)" "unprognostic (6.96e-2)" "unprognostic (5.00e-2)" "unprognostic (1.87e-1)" "unprognostic (7.17e-2)" "unprognostic (3.41e-2)" "prognostic favorable (3.45e-5)" "unprognostic (9.06e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (2.69e-4)" "unprognostic (1.12e-1)" "unprognostic (6.73e-2)" "unprognostic (1.25e-1)" 17.0 46.2 28.7 11.5 29.1 0.5 17.6 22.8 29.7 36.9 26.5 25.4 5.4 30.6 154.8 9.2 28.8 20.6 33.2 29.1 31.6 28.3 3.2 16.8 8.5 25.9 26.2 47.8 18.9 71.2 78.3 26.3 27.5 28.3 7.9 15.3 44.5 67.9 6.2 6.5 13.0 32.3 23.4 21.3 16.3 5.8 28.1 7.7 59.7 7.5 6.5 26.9 20.1 25.4 0.0 0.0 50.8 0.4 43.6 39.4 0.4 56.0 70.4 1.4 1.4 0.0 21.8 0.0 0.0 74.6 0.0 1.5 0.0 1.3 0.6 0.0 2.0 0.2 60.9 0.0 46.4 0.4 0.1 63.7 17.6 43.5 0.4 68.3 59.7 0.0 0.2 0.3 164.1 0.0 0.0 0.6 117.2 3.4 0.3 14.5 88.9 0.3 2.8 0.0 20.4 36.6 0.0 0.2 1.7 90.3 25.9 0.1 13.0 61.9 65.1 38.8 0.4 0.0 0.0 0.2 55.7 0.1 1.2 0.0 0.4 0.0 1.0 0.9 0.4 2.8 0.9 0.9 0.7 4.0 2.4 2.5 0.0 2.8 0.6 0.9 0.7 1.1 28.7 29.1 22.8 29.7 29.1 31.6 25.9 26.2 27.5 23.4 28.1 25.4 10.4 16.0 6.4 8.5 8.2 4.2 16.4 5.8 21.1 12.5 18.0 20.8 28.7 5.7 11.4 33.1 8.4 1.2 2.4 0.1 3.9 9.6 0.2 11.2 23.4 13.3 9.1 3.2 15.4 2.0 0.7 28.4 4.6 15.2 2.5 18.1 19.2 0.7 3.8 1.7 14.3 3.0 2.0 2.4 6.5 1.3 24.2 7.4 5.4 11.2 7.1 9.3 0.0 16.1 14.0 2.2 0.1 24.5 2.8 16.5 0.3 4.3 4.9 11.3 59.2 31.8 23.9 1.4 1.9 3.8 3.0 5.1 2.5 4.6 1.6 7.2 AS3MT CYT19 ENSG00000214435 "Arsenite methyltransferase" Q9HBK9 10 102869470-102901899 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "adrenal gland: 302.4" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.1;Basal squamous epithelial cells: 1.2;Proximal tubular cells: 1.0" "Cancer enhanced" "Detected in single" "liver cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 26.8;REH: 54.6;SH-SY5Y: 27.8;T-47d: 43.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017856 Enhanced Approved Mitochondria NA NA "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 50: Fibroblasts - ECM organization" Mitochondria "HPA017856: AB_1847420" "unprognostic (1.11e-1)" "unprognostic (2.02e-4)" "unprognostic (2.45e-1)" "unprognostic (2.25e-1)" "unprognostic (3.39e-1)" "unprognostic (1.66e-1)" "unprognostic (7.02e-4)" "unprognostic (3.22e-1)" "unprognostic (1.42e-1)" "unprognostic (3.90e-2)" "unprognostic (2.03e-1)" "unprognostic (1.83e-1)" "unprognostic (3.83e-10)" "unprognostic (1.04e-2)" "unprognostic (4.17e-2)" "unprognostic (1.59e-1)" "unprognostic (2.16e-2)" 5.1 302.4 7.4 1.3 7.5 0.7 6.3 11.5 8.7 7.5 9.3 6.4 3.0 7.7 4.4 3.6 5.8 6.7 26.8 6.7 8.4 19.2 59.2 4.0 2.0 7.9 8.3 8.7 11.7 65.7 6.6 1.0 8.0 9.1 1.8 4.8 4.8 5.2 11.4 4.3 3.3 3.9 6.6 18.3 4.7 8.7 7.7 3.7 7.7 15.2 1.6 3.2 5.0 8.3 0.0 7.6 26.8 17.4 0.6 0.6 5.1 8.1 6.7 11.9 14.3 21.3 1.2 0.0 2.4 10.7 0.6 0.4 23.8 1.4 12.4 0.3 6.7 0.0 3.2 20.9 7.7 0.2 0.6 3.7 3.1 1.6 0.0 21.3 0.5 25.3 0.0 0.4 10.8 0.1 4.9 0.7 13.2 0.1 1.0 54.6 0.0 0.2 2.7 0.0 0.4 27.8 0.0 0.4 3.7 8.8 43.9 0.6 0.1 2.6 0.0 3.9 0.0 0.2 0.4 0.0 8.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 7.4 7.5 11.5 8.7 6.7 8.4 7.9 8.3 8.0 6.6 7.7 8.3 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 ASB18 ENSG00000182177 "Ankyrin repeat and SOCS box containing 18" Q6ZVZ8 2 236194872-236264409 "Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 4.8;heart muscle: 7.4;skeletal muscle: 11.3" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 6.5;Excitatory neurons: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA068447 Approved Nucleoli,Mitochondria NA NA "Cluster 39: Non-specific - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria Nucleoli "HPA068447: AB_2685991" "unprognostic (1.12e-1)" "unprognostic (7.33e-3)" "unprognostic (3.07e-1)" "unprognostic (1.78e-6)" "unprognostic (4.75e-2)" "unprognostic (3.22e-1)" 0.0 0.0 0.6 0.0 4.8 0.0 0.0 1.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 1.0 0.6 0.0 0.0 0.0 0.0 2.3 2.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 11.3 0.0 0.0 0.0 1.5 0.0 0.0 0.5 3.3 0.0 0.0 1.6 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 4.8 1.0 1.0 1.0 0.6 2.3 2.0 1.4 1.5 3.3 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.9 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ATAD1 "FLJ14600, Msp1" ENSG00000138138 "ATPase family AAA domain containing 1" Q8NBU5 10 87751512-87841361 "Disease related genes, Human disease related genes, Predicted membrane proteins" Translocase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 16 "Early spermatids: 987.5;Late spermatids: 1846.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037569 Uncertain Approved "Nucleoli rim,Mitochondria" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 34: Spermatids - Unknown function" "Nucleoli rim" Mitochondria "HPA037569: AB_10672496" "unprognostic (9.92e-2)" "unprognostic (2.90e-1)" "unprognostic (4.05e-2)" "unprognostic (2.68e-1)" "unprognostic (3.24e-2)" "unprognostic (6.60e-3)" "unprognostic (3.38e-1)" "unprognostic (1.40e-1)" "unprognostic (2.35e-1)" "unprognostic (8.45e-2)" "unprognostic (1.35e-3)" "unprognostic (1.67e-2)" "prognostic favorable (3.98e-6)" "unprognostic (2.35e-1)" "unprognostic (3.29e-1)" "unprognostic (3.45e-2)" "unprognostic (4.22e-2)" 15.7 17.4 9.9 9.0 10.3 4.9 16.3 11.3 12.6 16.0 10.7 18.2 10.9 16.8 13.7 16.2 13.8 10.5 36.1 10.4 11.5 16.7 18.0 14.5 11.8 10.7 11.5 15.9 12.7 28.5 13.4 15.2 11.1 18.7 14.5 28.0 14.9 16.1 37.2 15.1 12.5 13.6 10.0 10.0 13.6 26.4 11.0 13.8 17.4 31.8 12.1 15.5 16.0 10.2 18.8 18.2 20.8 18.2 27.4 29.5 14.4 19.7 33.4 19.6 20.6 14.6 53.8 17.6 15.4 17.3 9.8 31.3 18.9 14.4 21.2 18.6 26.4 15.3 24.0 18.8 30.5 41.7 8.0 23.0 45.4 20.7 42.1 37.2 12.7 14.1 15.9 20.7 22.7 11.2 23.1 22.9 16.4 13.9 10.0 15.8 13.2 19.2 28.9 13.4 14.2 31.5 20.3 12.3 32.0 21.0 29.1 18.0 19.3 16.2 13.9 11.2 24.5 25.4 39.4 22.5 20.8 23.7 11.5 8.4 2.8 4.9 6.3 4.9 10.3 7.2 7.3 8.3 5.4 5.7 9.1 8.6 1.7 8.6 6.9 4.6 7.6 5.7 9.9 10.3 11.3 12.6 10.4 11.5 10.7 11.5 11.1 10.0 11.0 10.2 31.0 54.5 28.0 46.4 41.4 26.8 42.9 46.2 44.3 50.4 29.8 20.8 81.3 27.1 44.9 22.0 35.5 37.7 35.2 33.8 23.5 37.0 987.5 22.3 38.3 21.7 22.8 24.6 69.0 28.0 33.2 35.6 32.6 28.7 29.2 23.1 20.0 28.9 27.3 70.7 73.1 22.9 50.8 18.0 20.1 1846.8 35.8 25.1 32.0 37.5 16.1 59.6 23.7 58.8 52.7 39.0 25.2 47.0 32.3 42.3 20.5 29.5 44.8 54.8 59.2 29.5 43.8 77.2 29.8 34.6 30.1 88.4 40.0 34.8 23.7 54.6 ATAD3C FLJ34599 ENSG00000215915 "ATPase family AAA domain containing 3C" Q5T2N8 1 1449689-1470163 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 19.8;Collecting duct cells: 20.2;Distal tubular cells: 45.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 4 "RPMI-8226: 13.1" HPA065305 Approved Mitochondria NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA065305: AB_2685459" "unprognostic (9.23e-2)" "unprognostic (3.48e-2)" "unprognostic (3.20e-2)" "unprognostic (4.35e-3)" "unprognostic (1.11e-2)" "unprognostic (1.71e-2)" "unprognostic (3.79e-2)" "prognostic favorable (5.15e-4)" "unprognostic (1.23e-1)" "unprognostic (1.57e-1)" "unprognostic (1.22e-1)" "unprognostic (2.65e-1)" "unprognostic (3.80e-2)" "unprognostic (1.83e-1)" "unprognostic (5.74e-2)" "unprognostic (2.22e-1)" "unprognostic (2.12e-3)" 1.1 0.2 5.3 0.9 6.3 0.5 1.6 5.2 6.4 2.0 4.3 2.3 0.6 1.7 1.2 1.1 2.0 0.7 0.9 5.5 6.2 4.3 5.2 1.5 0.4 6.7 6.0 1.1 4.6 0.1 1.8 0.3 6.4 4.0 0.3 1.2 2.6 2.0 0.2 0.8 0.8 0.7 5.5 0.4 0.7 1.2 6.1 0.4 4.0 0.0 0.5 2.9 1.4 10.1 0.2 0.0 0.2 0.3 0.3 0.0 0.2 0.1 0.0 0.2 0.0 1.2 2.5 0.2 0.3 0.1 0.1 0.3 1.0 0.4 0.1 0.1 1.0 0.2 0.9 1.6 0.2 0.2 0.2 0.0 0.1 0.1 0.7 0.0 0.0 0.3 0.2 3.0 0.1 0.7 0.3 0.8 0.5 0.1 0.2 0.3 0.1 13.1 0.8 0.2 2.0 0.7 0.0 0.5 0.1 2.1 2.6 0.2 0.2 0.1 0.2 0.3 0.1 1.4 2.1 0.4 0.1 0.3 0.0 0.8 0.1 0.3 0.3 0.1 1.2 0.5 0.4 0.3 0.0 0.3 0.5 0.4 0.5 0.5 0.1 0.1 0.6 0.2 5.3 6.3 5.2 6.4 5.5 6.2 6.7 6.0 6.4 5.5 6.1 10.1 2.5 6.4 19.8 0.7 4.2 3.4 3.5 1.3 4.6 5.0 17.4 14.4 4.6 0.0 2.7 20.2 16.7 0.7 2.0 2.0 45.0 5.3 0.4 3.6 3.8 4.2 4.2 0.0 1.0 9.2 0.3 1.8 0.0 6.1 3.8 0.6 1.8 6.8 1.8 6.7 0.6 1.9 0.0 2.9 2.5 1.4 1.2 0.7 3.6 2.8 0.5 2.8 4.1 1.0 10.8 4.4 0.3 4.9 8.4 3.0 1.3 16.2 1.3 9.1 0.0 7.3 1.6 0.5 1.5 1.5 5.7 0.8 3.6 4.2 1.3 3.1 ATOH1 "bHLHa14, HATH1, MATH-1, Math1" ENSG00000172238 "Atonal bHLH transcription factor 1" Q92858 4 93828753-93830964 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "intestine: 20.0" "Cell type enriched" "Detected in some" 30 "Intestinal goblet cells: 226.1" "Cancer enriched" "Detected in some" 4 "colorectal cancer: 9.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA049400 Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 9: Intestine - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" Mitochondria "Nucleoplasm, Cytosol" "HPA049400: " "prognostic favorable (3.26e-5)" "unprognostic (5.20e-1)" "unprognostic (2.69e-1)" "unprognostic (1.26e-1)" "unprognostic (2.70e-1)" 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.0 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.4 0.0 0.0 0.0 0.0 0.1 20.0 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 226.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.0 0.0 ATP5MF-PTCD1 ATP5J2-PTCD1 ENSG00000248919 "ATP5MF-PTCD1 readthrough" 7 99419749-99466197 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA020106, HPA047679" Uncertain Approved Mitochondria NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 11: Alveolar cells - Smell perception" Mitochondria "HPA020106: AB_2176551, HPA047679: AB_2680119" "unprognostic (1.15e-3)" "unprognostic (3.63e-2)" "unprognostic (1.73e-1)" "unprognostic (2.83e-1)" "unprognostic (3.29e-2)" "unprognostic (3.51e-1)" "unprognostic (1.18e-3)" "unprognostic (2.84e-2)" "unprognostic (6.44e-2)" "unprognostic (2.18e-1)" "unprognostic (3.50e-2)" "unprognostic (1.28e-1)" "unprognostic (1.70e-1)" "unprognostic (2.04e-1)" "unprognostic (7.45e-2)" "unprognostic (2.00e-2)" "unprognostic (7.50e-2)" 2.8 2.8 1.2 2.8 1.0 0.0 2.3 1.1 1.8 3.3 1.1 3.7 2.7 3.0 1.6 4.7 3.3 2.0 3.7 1.0 1.2 1.7 2.7 1.8 2.6 1.3 1.4 2.5 2.5 3.6 1.7 2.5 1.3 3.7 2.1 0.5 2.5 3.5 8.9 2.7 2.2 2.5 0.9 2.3 2.7 3.4 1.2 2.3 2.3 5.5 2.5 4.1 3.3 1.1 7.7 8.2 6.8 19.1 8.1 4.8 14.6 5.1 6.2 12.8 11.6 31.5 12.3 10.0 12.6 4.9 11.9 7.3 11.6 10.6 5.4 11.2 10.9 5.8 5.0 6.5 8.5 8.0 5.7 8.2 9.4 11.5 9.3 4.7 5.3 11.5 19.5 14.9 8.3 15.7 18.5 10.2 11.9 13.2 10.5 9.9 6.3 26.6 6.7 2.4 8.7 8.8 11.0 18.0 11.0 4.5 9.2 12.5 3.3 8.9 7.8 18.7 13.8 11.7 10.8 16.0 6.5 8.9 16.3 1.3 4.0 1.2 3.3 5.4 3.4 2.1 2.7 2.8 5.6 2.4 2.8 3.6 0.3 4.5 3.2 2.7 2.2 5.0 1.2 1.0 1.1 1.8 1.0 1.2 1.3 1.4 1.3 0.9 1.2 1.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 ATP5PO "ATP5O, ATPO, OSCP" ENSG00000241837 "ATP synthase peripheral stalk subunit OSCP" P48047 21 33903453-33915814 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 1601.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 610.3;Distal tubular cells: 1794.2;Extravillous trophoblasts: 623.2;Hofbauer cells: 627.0;Proximal tubular cells: 1236.8;Syncytiotrophoblasts: 542.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016209, HPA041394" Enhanced Approved Mitochondria NA NA 150000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 7: Non-specific - Mitochondria" Mitochondria "CAB016209: AB_631361, HPA041394: AB_2677450" "unprognostic (2.08e-1)" "unprognostic (4.77e-3)" "unprognostic (3.30e-1)" "unprognostic (6.12e-3)" "unprognostic (1.51e-1)" "unprognostic (1.46e-1)" "unprognostic (1.48e-1)" "unprognostic (2.34e-1)" "unprognostic (8.47e-2)" "unprognostic (1.42e-1)" "unprognostic (3.27e-1)" "unprognostic (1.81e-1)" "prognostic favorable (9.34e-4)" "unprognostic (1.03e-1)" "unprognostic (1.37e-2)" "unprognostic (3.26e-2)" "unprognostic (7.89e-3)" 213.0 181.0 282.7 147.9 289.4 310.6 280.4 306.0 417.7 204.8 325.2 351.9 357.2 169.2 251.1 288.3 216.7 157.9 1114.5 291.2 317.4 458.0 401.8 148.9 243.3 298.2 290.8 273.1 196.7 432.9 108.0 192.2 296.5 158.0 391.9 219.4 236.3 202.0 1063.7 188.4 293.8 217.4 290.9 143.4 304.2 150.3 291.4 281.7 224.4 1601.7 292.9 242.3 161.6 292.4 398.4 187.3 491.1 486.6 340.0 435.1 554.6 218.5 394.4 371.4 361.9 553.5 372.7 531.5 187.2 345.1 355.2 217.5 549.0 764.7 440.6 400.0 544.0 790.3 260.4 513.5 389.7 603.7 260.9 445.8 467.9 358.4 581.9 407.0 522.8 421.2 656.3 665.9 488.5 402.5 461.6 593.0 561.3 992.2 540.1 471.6 490.1 1007.5 1032.8 337.0 404.4 232.1 380.2 559.7 525.7 425.6 562.9 660.5 291.0 236.8 280.6 423.0 252.6 429.1 524.2 559.7 438.2 1046.2 349.3 329.7 561.5 407.8 335.9 596.2 400.9 575.4 439.5 404.8 753.0 487.3 540.9 459.4 136.2 412.6 539.8 445.4 585.3 1077.9 282.7 289.4 306.0 417.7 291.2 317.4 298.2 290.8 296.5 290.9 291.4 292.4 195.8 243.6 191.1 0.0 82.1 0.0 0.0 0.0 0.0 0.0 282.6 476.1 0.0 0.0 121.3 222.5 0.0 610.3 81.3 0.0 1794.2 394.5 0.0 133.0 140.9 87.3 0.0 0.0 0.0 420.2 623.2 109.7 0.0 114.8 114.8 198.9 0.0 0.0 627.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 131.2 0.0 0.0 218.1 0.0 0.0 0.0 0.0 331.9 0.0 0.0 17.8 0.0 0.0 1236.8 102.0 0.0 0.0 0.0 119.0 0.0 0.0 0.0 0.0 542.1 67.4 208.9 0.0 0.0 ATPAF1 "ATP11, Atp11p, FLJ22351" ENSG00000123472 "ATP synthase mitochondrial F1 complex assembly factor 1" Q5TC12 1 46632737-46673867 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 263.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 284.7;Distal tubular cells: 172.1;Early spermatids: 261.4;Late spermatids: 373.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028382, HPA044950" Approved Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 5: NTERA-2 - Transcription" "Cluster 34: Spermatids - Unknown function" Mitochondria "HPA028382: AB_2672574, HPA044950: AB_2679151" "unprognostic (1.34e-1)" "unprognostic (2.97e-3)" "unprognostic (1.18e-2)" "unprognostic (5.96e-2)" "unprognostic (1.20e-1)" "unprognostic (5.97e-2)" "unprognostic (3.53e-1)" "unprognostic (1.72e-2)" "unprognostic (1.70e-2)" "unprognostic (1.19e-2)" "unprognostic (5.15e-2)" "unprognostic (1.05e-1)" "prognostic favorable (5.33e-7)" "unprognostic (1.36e-1)" "unprognostic (6.52e-2)" "unprognostic (2.44e-1)" "unprognostic (2.62e-1)" 66.0 89.9 87.5 23.3 94.4 27.4 30.2 97.1 115.2 30.0 102.8 44.9 35.3 22.5 29.4 30.1 27.3 25.8 221.0 82.9 107.7 97.1 95.3 21.9 27.9 85.8 85.6 28.8 41.2 121.5 43.8 32.3 85.3 32.2 48.1 63.9 48.4 29.0 221.0 20.1 35.2 32.3 80.7 21.6 42.1 41.5 90.6 37.8 37.1 263.4 28.5 26.4 20.2 82.2 57.8 46.1 61.1 54.8 65.1 52.3 51.0 42.2 52.6 62.0 49.7 37.2 24.5 34.1 55.2 53.6 54.9 43.6 97.3 54.7 83.1 75.0 76.7 60.2 54.5 65.0 52.4 60.2 3.4 51.4 64.3 66.5 57.7 49.2 39.3 62.8 28.2 65.4 48.0 52.3 89.3 33.3 96.3 49.8 68.8 38.1 16.5 74.3 71.4 45.2 71.8 53.8 71.4 74.9 114.6 70.0 69.3 83.8 34.4 21.1 52.1 43.1 58.5 80.6 78.9 23.2 34.7 23.0 40.6 0.0 1.6 4.1 2.1 2.8 2.7 1.8 2.2 2.5 1.6 1.2 3.1 1.4 1.3 5.6 1.2 1.2 4.5 1.2 87.5 94.4 97.1 115.2 82.9 107.7 85.8 85.6 85.3 80.7 90.6 82.2 12.6 3.2 18.6 31.0 22.3 9.4 21.2 9.7 27.3 34.0 27.8 19.4 284.7 31.5 13.1 31.3 27.1 64.0 14.5 26.7 172.1 22.1 261.4 15.6 15.4 13.2 19.2 31.3 37.1 20.1 30.0 28.5 29.0 15.9 15.9 40.6 10.4 39.8 39.2 47.1 48.5 38.1 16.2 21.6 12.9 373.7 19.0 16.1 24.9 15.9 14.6 39.2 15.5 28.1 33.7 11.3 18.0 26.7 36.3 15.2 30.2 119.1 10.2 29.2 26.3 25.1 28.9 45.2 40.4 34.3 13.5 46.9 19.2 55.1 42.2 21.9 ATRNL1 "ALP, FLJ45344, KIAA0534" ENSG00000107518 "Attractin like 1" Q5VV63 10 115093365-115948999 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 91.1" "Group enriched" "Detected in many" 13 "Excitatory neurons: 2134.6;Inhibitory neurons: 1473.4;Oligodendrocyte precursor cells: 1456.7" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "cerebral cortex: 91.1;white matter: 58.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 21.4;RH-30: 18.4;U-266/70: 14.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038070 Approved Nucleoplasm,Mitochondria NA NA 160000000 "Cluster 10: Brain - Neuronal signaling" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Mitochondria" "HPA038070: AB_10697237" "unprognostic (3.85e-2)" "unprognostic (1.89e-1)" "unprognostic (5.88e-2)" "unprognostic (3.20e-3)" "unprognostic (1.57e-2)" "unprognostic (3.33e-1)" "unprognostic (1.11e-1)" "unprognostic (1.88e-2)" "unprognostic (5.17e-2)" "unprognostic (4.06e-2)" "unprognostic (2.18e-2)" "unprognostic (2.50e-2)" "unprognostic (1.04e-3)" "unprognostic (3.10e-2)" "unprognostic (2.76e-2)" "unprognostic (1.88e-2)" "unprognostic (2.08e-3)" 0.7 10.7 3.8 0.2 9.5 0.0 1.0 0.0 91.1 0.9 0.0 2.4 0.3 6.2 0.3 0.5 1.0 0.2 1.8 18.3 0.0 2.8 1.5 0.1 0.4 0.0 0.2 9.7 1.3 2.1 5.8 1.9 1.0 3.1 0.2 6.3 1.0 3.8 2.8 0.2 0.8 5.8 0.0 0.3 0.4 12.6 0.0 0.4 1.0 0.0 0.4 0.6 1.0 58.7 0.0 0.6 6.3 21.4 0.0 0.0 0.0 0.1 0.6 3.9 4.6 0.2 0.2 0.0 1.5 0.5 5.1 0.0 1.6 0.0 4.0 0.1 4.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.1 6.4 0.0 11.3 0.0 5.3 10.4 0.2 9.9 0.0 9.1 0.0 0.1 7.5 18.4 11.4 3.9 0.0 3.6 10.5 0.0 0.1 0.4 4.3 1.8 0.0 0.0 0.0 2.7 0.1 3.3 14.2 0.0 4.6 0.1 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 9.5 0.0 91.1 18.3 0.0 0.0 0.2 1.0 0.0 0.0 58.7 0.0 0.0 0.0 55.8 0.8 0.6 0.1 0.8 0.6 35.4 2.1 0.5 2.5 0.0 0.1 0.0 2.1 0.1 0.2 0.2 0.0 0.7 45.6 0.8 1.5 1.5 0.0 0.0 2134.6 0.4 0.0 5.3 0.0 1.8 0.0 24.9 21.0 0.1 3.0 10.1 1473.4 0.0 0.0 1.9 0.4 47.8 1.5 0.3 0.0 128.4 0.0 4.3 0.0 1456.7 34.2 0.3 0.0 0.7 0.0 0.1 0.0 0.5 0.1 4.7 0.0 2.4 2.6 46.6 11.5 0.0 0.1 0.3 0.1 53.1 0.0 0.1 B3GNT4 "B3GN-T4, beta3Gn-T4" ENSG00000176383 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4" Q9C0J1 12 122203681-122208952 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.9;skin 1: 3.1" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 3.3;Excitatory neurons: 3.2;Proximal tubular cells: 9.7;Spermatogonia: 2.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 5.1;hTCEpi: 4.0;T-47d: 4.2;U-266/84: 3.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA055261 Uncertain Approved Nucleoli,Mitochondria NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 44: HDLM-2 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria Nucleoli "HPA055261: AB_2682765" "unprognostic (1.67e-1)" "unprognostic (1.66e-1)" "unprognostic (1.27e-1)" "unprognostic (2.36e-1)" "unprognostic (1.10e-2)" "unprognostic (2.60e-2)" "unprognostic (1.32e-3)" "unprognostic (1.98e-1)" "unprognostic (3.44e-2)" "unprognostic (1.21e-1)" "unprognostic (3.82e-2)" "unprognostic (3.69e-1)" "prognostic unfavorable (3.52e-6)" "unprognostic (1.24e-1)" "unprognostic (2.79e-1)" "unprognostic (8.97e-2)" "unprognostic (9.47e-2)" 0.2 0.7 2.3 0.1 2.6 1.5 0.2 4.9 3.1 0.3 0.0 0.3 0.2 0.1 0.0 1.3 0.6 0.2 0.1 3.8 0.5 2.7 0.4 0.3 0.1 0.0 0.0 0.2 0.3 0.3 1.4 0.1 0.0 0.4 0.0 0.5 0.5 0.0 0.2 3.1 0.3 0.0 0.0 0.5 0.3 1.6 0.9 0.0 0.4 0.0 0.1 0.1 0.5 1.2 3.4 0.6 0.2 1.4 0.1 0.1 0.6 0.1 0.0 0.2 0.3 2.2 0.3 0.3 0.5 0.0 0.2 1.3 1.7 1.2 0.1 5.1 1.9 0.1 1.3 0.2 0.4 0.5 0.7 0.3 4.0 0.1 0.2 0.5 0.0 1.3 1.0 0.4 0.0 3.2 0.0 0.5 0.4 0.1 1.4 0.2 0.4 0.7 0.5 0.4 0.8 1.1 0.9 0.7 0.4 0.5 4.2 0.1 0.1 0.3 1.7 0.4 0.2 0.4 3.6 0.8 0.3 0.5 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.1 0.0 0.0 2.3 2.6 4.9 3.1 3.8 0.5 0.0 0.0 0.0 0.0 0.9 1.2 0.4 0.0 1.8 0.7 0.3 1.3 0.7 3.3 0.6 0.2 0.7 0.8 0.5 0.0 1.1 0.0 0.0 0.5 0.5 0.6 1.9 1.0 0.4 0.6 0.3 0.3 0.0 0.0 3.2 0.2 1.1 0.3 0.0 0.8 0.0 0.1 0.4 0.0 0.2 0.0 1.4 0.0 2.0 0.6 0.6 0.1 0.3 0.3 0.0 1.9 0.0 0.2 0.0 0.5 0.6 0.4 1.3 0.0 0.4 0.3 0.1 9.7 1.1 0.2 0.0 0.5 0.2 0.8 2.9 0.8 1.4 0.5 0.4 0.1 0.3 0.4 BCL2L1 "Bcl-X, bcl-xL, bcl-xS, BCL2L, BCLX, PPP1R52" ENSG00000171552 "BCL2 like 1" Q07817 20 31664452-31723989 "Cancer-related genes, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Apoptosis, Endocytosis" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 160.0;Pancreatic endocrine cells: 187.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035734, CAB072801" Approved Approved Mitochondria NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 39: CACO-2 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" Mitochondria "CAB072801: , HPA035734: AB_2674757" "unprognostic (2.29e-1)" "unprognostic (5.40e-3)" "unprognostic (1.78e-2)" "prognostic unfavorable (9.10e-4)" "unprognostic (1.37e-1)" "unprognostic (1.09e-1)" "unprognostic (5.04e-2)" "unprognostic (7.82e-3)" "prognostic favorable (9.57e-4)" "unprognostic (1.67e-1)" "prognostic unfavorable (5.87e-4)" "unprognostic (1.06e-1)" "prognostic favorable (8.89e-5)" "unprognostic (9.67e-2)" "unprognostic (3.03e-2)" "unprognostic (2.02e-2)" "unprognostic (3.32e-2)" 80.3 46.9 46.3 26.1 53.7 99.0 71.0 46.7 54.5 46.5 88.2 42.4 49.4 39.2 11.9 77.8 42.7 51.7 77.9 42.2 48.2 95.7 85.2 95.1 25.8 49.5 49.4 23.1 54.7 30.4 49.8 42.0 51.1 52.0 26.2 41.0 70.6 25.2 55.4 65.7 48.9 25.0 41.3 53.4 66.6 46.2 54.4 111.5 51.4 38.8 28.9 42.8 54.7 59.7 327.0 188.4 30.7 32.4 167.8 123.1 101.0 73.8 113.2 69.6 66.4 429.2 150.9 48.2 176.7 108.4 140.7 105.8 42.9 216.7 46.2 55.1 8.6 231.3 34.4 231.6 123.0 19.6 137.7 90.7 77.4 89.4 194.0 102.4 106.0 81.6 150.0 34.5 238.7 94.3 73.9 20.6 45.4 150.8 153.2 43.5 92.9 164.3 249.3 83.4 85.4 38.4 89.3 92.6 42.4 57.2 180.5 26.3 154.1 90.0 109.1 36.8 139.4 22.7 150.7 37.9 143.5 99.5 59.5 28.6 11.0 25.6 39.9 11.7 30.9 4.8 17.1 26.8 10.4 6.0 7.7 18.6 12.5 19.8 13.4 7.0 21.8 28.2 46.3 53.7 46.7 54.5 42.2 48.2 49.5 49.4 51.1 41.3 54.4 59.7 41.6 16.0 9.2 22.5 10.1 18.4 70.2 40.8 26.7 21.9 25.5 15.4 9.7 91.5 36.3 38.6 45.9 27.1 13.7 41.7 86.1 92.2 10.2 71.4 14.6 35.8 24.7 160.0 21.8 65.9 11.3 15.5 37.2 58.2 12.7 10.6 36.4 40.8 38.2 28.6 19.5 26.0 69.2 22.1 13.3 4.6 19.0 27.6 17.8 49.6 76.9 24.1 54.6 13.6 55.6 187.7 22.4 42.9 38.0 102.9 54.6 76.5 76.4 33.7 46.0 14.9 42.7 31.0 15.1 13.6 9.8 18.9 24.9 13.6 19.6 143.0 BDH1 "BDH, SDR9C1" ENSG00000161267 "3-hydroxybutyrate dehydrogenase 1" Q02338 3 197509783-197573323 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Allosteric enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 324.0" "Cell type enhanced" "Detected in many" "Hepatocytes: 112.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 44.2;U-937: 75.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA030947, HPA058709" Enhanced Approved Mitochondria NA NA "Cluster 30: Non-specific - Translation" "Cluster 85: Liver - Metabolism" "Cluster 32: U-937 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA030947: AB_10669548, HPA058709: AB_2683797" "unprognostic (2.72e-2)" "prognostic favorable (1.09e-4)" "unprognostic (1.13e-1)" "unprognostic (3.93e-1)" "unprognostic (3.35e-2)" "unprognostic (1.07e-1)" "prognostic favorable (9.86e-7)" "unprognostic (2.08e-1)" "unprognostic (3.85e-2)" "unprognostic (4.53e-2)" "unprognostic (5.17e-3)" "unprognostic (5.85e-3)" "prognostic favorable (7.12e-8)" "unprognostic (5.62e-2)" "unprognostic (1.74e-1)" "unprognostic (6.22e-2)" "unprognostic (1.02e-1)" 9.6 6.8 14.4 4.1 17.9 7.3 9.7 18.4 19.8 6.8 30.8 45.1 17.4 6.3 3.9 48.0 9.7 3.8 52.4 16.5 14.3 19.2 324.0 5.2 3.9 14.3 13.8 8.2 7.0 15.5 12.6 0.3 14.4 16.2 19.8 9.3 25.3 4.1 21.5 30.4 28.1 2.2 12.9 7.9 16.6 4.5 16.3 6.1 17.7 22.8 7.1 9.9 14.7 14.2 23.7 2.9 1.2 11.3 1.9 0.1 0.0 2.8 2.2 11.4 6.3 20.5 7.5 0.2 33.0 0.7 0.9 10.3 10.0 5.4 4.2 0.3 0.0 12.0 8.3 7.0 8.3 27.0 12.3 3.4 6.0 4.4 9.4 1.2 2.8 13.7 0.0 8.4 0.2 40.9 20.5 18.8 8.2 44.2 4.2 19.6 4.1 31.5 12.3 9.9 20.1 8.8 8.2 1.1 4.5 0.5 26.3 22.7 0.3 0.7 3.9 0.1 21.6 10.4 20.5 0.3 0.7 75.8 1.5 2.9 1.3 0.6 4.6 0.2 6.4 5.1 5.1 4.2 3.5 4.6 7.6 4.7 0.0 4.5 0.2 3.8 3.7 3.4 14.4 17.9 18.4 19.8 16.5 14.3 14.3 13.8 14.4 12.9 16.3 14.2 0.4 3.2 9.4 27.7 7.0 9.3 8.5 10.0 16.5 21.3 20.3 14.7 36.7 17.2 13.8 12.9 20.9 2.0 7.1 68.9 52.8 6.6 9.5 34.1 3.6 2.2 27.2 6.7 60.5 5.6 5.1 2.8 17.3 16.5 1.3 6.6 5.0 112.3 8.9 18.5 58.0 43.2 10.2 5.4 8.5 13.9 5.6 3.5 16.0 8.4 1.0 17.5 11.3 27.2 12.5 3.0 36.4 4.1 5.4 6.5 62.8 30.2 48.0 33.6 0.0 2.4 3.7 16.8 4.9 36.3 10.9 1.9 8.5 10.0 68.7 13.1 BMP6 "VGR, VGR1" ENSG00000153162 "Bone morphogenetic protein 6" P22004 6 7726099-7881728 "Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 23.0;Hepatic stellate cells: 16.8;Inhibitory neurons: 22.8;Microglial cells: 74.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 11 "granulocytes: 1.1" "Cell line enhanced" "Detected in many" "EFO-21: 37.0;HUVEC TERT2: 149.6;Karpas-707: 81.6;SiHa: 70.0;TIME: 74.3;U-266/84: 41.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002773, HPA062683" Approved Approved Mitochondria "Secreted to blood" No No 4970000 46000 "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "CAB002773: , HPA062683: AB_2684832" "prognostic favorable (6.45e-4)" "unprognostic (2.99e-1)" "unprognostic (4.20e-1)" "unprognostic (6.71e-2)" "unprognostic (2.44e-1)" "unprognostic (7.27e-2)" "unprognostic (4.66e-2)" "unprognostic (1.29e-1)" "unprognostic (1.26e-1)" "unprognostic (6.94e-2)" "unprognostic (2.80e-2)" "unprognostic (2.02e-1)" "unprognostic (1.26e-1)" "unprognostic (1.82e-2)" "unprognostic (8.29e-2)" "unprognostic (2.95e-1)" "unprognostic (2.29e-3)" 16.5 3.1 5.1 2.2 5.9 0.4 12.7 3.9 6.2 3.2 7.8 3.7 3.0 3.5 0.6 2.0 2.4 2.1 5.1 3.9 3.7 17.8 1.9 9.1 1.5 4.9 4.5 8.2 0.6 0.6 4.6 18.1 4.7 2.8 2.7 0.1 2.3 2.6 3.1 3.5 3.0 2.3 4.8 4.6 4.7 2.2 5.7 0.9 1.5 1.3 2.4 3.3 3.0 4.1 0.9 2.4 0.3 0.0 0.4 0.3 0.0 2.0 0.1 0.0 0.0 0.0 0.0 0.0 37.0 1.1 1.6 0.5 1.1 0.2 0.0 0.0 5.7 15.9 21.8 1.4 0.8 1.1 16.7 0.0 0.0 0.7 2.4 9.6 149.6 0.0 0.0 81.6 0.0 0.3 0.0 0.0 0.8 0.5 12.0 0.6 0.0 15.3 0.5 0.0 12.3 0.0 70.0 0.0 0.0 9.3 0.0 0.0 74.3 0.0 4.7 0.5 2.6 11.3 41.3 0.1 2.3 0.0 1.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.5 5.1 5.9 3.9 6.2 3.9 3.7 4.9 4.5 4.7 4.8 5.7 4.1 23.0 0.0 0.5 1.6 1.1 0.3 0.0 0.0 0.0 0.0 0.1 0.1 3.5 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.8 0.2 8.9 0.0 0.0 7.8 0.0 0.1 2.0 0.0 2.0 0.0 1.5 16.8 0.6 0.3 0.0 22.8 0.0 0.0 0.8 2.1 4.2 0.0 1.5 1.8 74.0 0.7 0.0 0.0 0.0 0.3 0.1 0.0 0.0 6.8 0.3 0.0 0.0 0.3 0.0 0.0 4.7 0.4 0.1 1.3 0.1 0.1 0.3 0.4 0.4 0.0 0.0 BPHL "Bph-rp, MCNAA, VACVase" ENSG00000137274 "Biphenyl hydrolase like" Q86WA6 6 3118374-3153578 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 110.4;liver: 84.8" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 99.7;Proximal tubular cells: 336.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036752, HPA036753" Enhanced Approved Mitochondria NA NA 14000 "Cluster 44: Non-specific - Transcription" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA036752: AB_10673662, HPA036753: AB_2675291" "unprognostic (2.93e-1)" "unprognostic (1.29e-1)" "unprognostic (8.88e-2)" "unprognostic (1.11e-1)" "unprognostic (3.72e-3)" "unprognostic (1.84e-1)" "unprognostic (8.65e-2)" "unprognostic (3.14e-2)" "unprognostic (1.94e-1)" "prognostic favorable (5.97e-4)" "unprognostic (4.59e-2)" "unprognostic (9.46e-3)" "prognostic favorable (5.16e-7)" "unprognostic (1.60e-2)" "unprognostic (1.51e-2)" "unprognostic (6.98e-2)" "unprognostic (5.20e-2)" 24.1 15.3 9.4 3.9 9.8 3.5 11.2 9.5 14.5 9.3 11.8 10.6 33.8 7.0 28.8 13.2 11.1 8.9 11.6 10.1 10.8 110.4 84.8 5.2 4.4 9.8 10.2 6.5 11.5 10.8 12.7 5.0 10.7 6.8 9.4 4.2 11.3 4.7 15.5 11.2 32.8 5.8 8.6 3.9 10.0 5.0 9.8 4.8 5.5 12.5 5.9 9.0 9.1 10.8 12.0 13.8 26.8 30.6 22.5 16.2 10.2 7.1 8.7 8.6 11.4 12.4 15.3 18.6 19.7 9.2 21.4 22.1 11.7 8.0 7.6 24.8 10.5 2.7 5.4 21.8 7.9 6.3 1.8 16.9 14.1 6.3 6.0 17.7 15.5 18.8 7.2 3.0 19.9 18.2 14.8 8.3 22.5 21.1 21.9 16.1 17.7 27.9 19.7 30.3 31.7 23.3 13.2 9.0 58.4 39.4 25.6 2.2 7.7 12.5 3.4 13.1 4.9 8.6 27.8 20.4 3.5 4.0 18.4 13.6 9.8 0.0 8.2 12.9 10.9 17.5 9.7 8.4 15.3 12.8 9.1 12.7 0.6 14.6 7.8 8.4 5.4 7.5 9.4 9.8 9.5 14.5 10.1 10.8 9.8 10.2 10.7 8.6 9.8 10.8 15.9 6.4 9.3 11.1 8.2 8.9 8.6 26.0 10.8 11.1 15.1 19.0 4.8 31.5 19.3 16.5 20.9 28.6 5.6 13.6 70.5 28.1 0.5 13.6 14.0 9.1 16.1 6.9 9.3 13.5 32.2 12.2 11.2 8.2 2.5 31.8 6.1 70.9 23.7 16.8 12.8 14.9 38.7 2.2 8.3 1.6 14.9 8.0 32.0 10.3 13.9 12.2 7.2 9.0 4.7 19.6 14.8 13.9 4.5 8.4 99.7 336.3 38.2 6.9 6.6 19.0 12.5 6.8 20.6 13.9 9.2 14.0 7.6 32.9 19.0 8.1 BRI3BP "BNAS1, HCCR-2, HCCRBP-3, KG19" ENSG00000184992 "BRI3 binding protein" Q8WY22 12 124993645-125031231 "Predicted membrane proteins, Transporters" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 20.8" "Cell type enhanced" "Detected in many" "Late spermatids: 174.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 13.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Daudi: 114.9;U-698: 161.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014957 Approved Approved Nucleoplasm,Mitochondria NA Yes "Cluster 52: Eosinophils - Transcription" "Cluster 45: Intestine - Brush border" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Mitochondria" "HPA014957: AB_1845447" "unprognostic (1.62e-2)" "unprognostic (6.82e-2)" "unprognostic (1.53e-2)" "unprognostic (9.95e-2)" "unprognostic (4.66e-2)" "unprognostic (1.20e-2)" "prognostic unfavorable (6.87e-4)" "unprognostic (7.65e-3)" "unprognostic (2.84e-2)" "unprognostic (3.47e-3)" "unprognostic (7.40e-2)" "unprognostic (4.82e-2)" "unprognostic (2.72e-3)" "unprognostic (1.44e-3)" "unprognostic (2.20e-1)" "unprognostic (9.20e-2)" "unprognostic (1.55e-1)" 3.3 2.0 9.2 8.9 10.7 5.5 5.5 8.2 10.7 3.0 7.1 15.5 20.8 2.1 2.2 6.8 4.1 4.8 2.5 9.2 7.9 6.9 4.8 2.8 13.8 9.6 9.7 1.5 5.1 9.1 2.1 2.1 10.2 2.9 15.3 10.0 2.5 2.2 1.7 5.5 18.8 2.6 9.1 5.9 8.2 1.8 9.1 7.0 4.4 2.1 16.2 2.5 2.6 9.4 34.1 43.8 13.8 12.5 10.9 5.6 24.1 22.2 4.6 13.7 7.1 36.1 22.3 114.9 27.8 5.0 8.9 38.7 30.7 17.3 10.9 26.9 25.5 58.4 16.9 24.8 2.2 86.8 72.2 2.5 9.9 15.0 7.1 5.3 5.1 41.0 23.5 8.0 12.0 31.3 45.1 33.3 9.9 29.9 17.3 30.2 23.0 30.7 17.3 46.8 19.0 13.2 27.6 26.9 9.2 4.6 48.8 60.8 5.9 13.0 16.2 12.5 23.4 26.9 49.7 161.8 11.9 28.7 29.1 4.2 2.2 13.1 0.8 1.6 0.8 1.4 0.6 0.7 1.7 1.5 0.5 0.7 2.2 0.9 1.2 4.2 0.7 0.6 9.2 10.7 8.2 10.7 9.2 7.9 9.6 9.7 10.2 9.1 9.1 9.4 3.4 9.6 10.4 13.4 23.6 12.2 9.1 8.2 5.2 37.1 14.9 6.3 7.2 31.5 9.2 9.2 14.6 15.4 24.3 65.5 3.9 9.1 25.6 16.1 7.2 5.1 7.8 21.5 32.6 10.4 24.0 7.1 32.1 18.0 18.4 7.2 4.2 27.4 19.8 25.2 43.8 42.8 8.2 31.5 26.1 174.4 1.2 23.6 10.6 11.2 28.8 12.1 9.2 11.1 23.4 17.1 43.3 4.1 39.5 9.6 60.2 12.7 15.0 27.9 0.0 9.2 6.9 1.1 11.5 20.7 18.3 5.2 11.5 6.8 72.6 9.7 BRPF3 KIAA1286 ENSG00000096070 "Bromodomain and PHD finger containing 3" Q9ULD4 6 36196744-36232790 "Plasma proteins, Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022787 Uncertain Approved Nucleoplasm,Mitochondria No No "Cluster 46: Basophils - DNA binding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Mitochondria "HPA022787: AB_1845454" "unprognostic (1.44e-1)" "unprognostic (2.24e-1)" "unprognostic (5.52e-2)" "unprognostic (2.15e-2)" "unprognostic (2.98e-1)" "unprognostic (9.51e-2)" "unprognostic (5.33e-2)" "unprognostic (3.78e-1)" "unprognostic (3.02e-2)" "unprognostic (1.07e-1)" "unprognostic (7.98e-2)" "unprognostic (3.74e-1)" "unprognostic (3.59e-2)" "unprognostic (3.29e-2)" "unprognostic (1.67e-1)" "unprognostic (1.28e-1)" "unprognostic (1.28e-1)" 6.6 11.9 3.5 7.6 4.3 12.1 8.4 9.0 5.4 8.4 0.1 13.1 11.7 11.9 6.1 7.9 8.8 8.6 7.3 5.5 1.9 11.8 6.9 7.4 6.2 0.6 1.4 11.9 18.0 14.5 4.4 7.5 0.7 9.6 12.9 6.4 15.7 10.9 12.1 12.6 13.8 10.2 0.3 9.0 10.7 19.9 2.1 9.4 12.1 12.2 6.2 7.4 4.7 4.0 10.6 10.0 24.6 19.4 13.3 11.2 21.0 15.6 16.3 21.5 16.9 29.4 9.8 16.3 16.4 15.4 27.0 10.0 21.8 11.2 18.8 15.6 13.5 11.5 9.3 17.6 14.0 9.1 15.5 14.4 9.4 25.6 12.8 15.6 16.3 7.7 24.5 14.6 11.9 15.0 10.4 3.9 12.4 12.9 8.5 29.9 10.1 5.1 6.9 21.4 35.0 11.0 12.7 13.8 12.9 15.1 15.4 24.6 17.2 22.3 18.9 6.1 18.3 12.0 16.8 12.1 3.7 14.1 26.9 0.7 0.0 0.3 0.4 0.0 0.4 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.4 0.0 0.0 0.1 0.2 0.1 3.5 4.3 9.0 5.4 5.5 1.9 0.6 1.4 0.7 0.3 2.1 4.0 5.7 6.4 12.7 8.8 5.6 9.6 7.2 4.6 9.6 9.0 21.1 11.7 13.7 10.0 7.3 5.5 6.2 4.8 9.7 28.1 0.0 6.6 15.3 7.3 10.9 7.2 19.7 5.7 16.6 10.8 4.1 9.8 10.2 12.7 2.5 16.6 9.7 18.2 4.5 0.0 11.4 27.5 6.1 5.7 6.6 14.0 11.1 4.9 7.2 6.5 5.4 6.1 9.2 13.6 11.0 11.2 13.6 9.4 10.5 11.3 21.5 13.5 4.5 7.2 0.0 11.1 8.0 25.7 17.5 7.3 11.4 8.2 6.3 14.2 16.2 10.2 BTN2A2 "BT2.2, BTF2, BTN2.2" ENSG00000124508 "Butyrophilin subfamily 2 member A2" Q8WVV5 6 26383096-26394874 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 30.3;Plasma cells: 30.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 72.8;U-266/70: 58.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA051504 Uncertain Approved Mitochondria NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 57: B-cells - Immune response" Mitochondria "HPA051504: AB_2681510" "prognostic favorable (1.01e-4)" "unprognostic (4.93e-3)" "unprognostic (1.37e-2)" "unprognostic (6.78e-2)" "unprognostic (9.26e-2)" "unprognostic (2.01e-2)" "unprognostic (1.78e-1)" "unprognostic (8.04e-3)" "unprognostic (1.01e-1)" "unprognostic (1.22e-2)" "unprognostic (6.67e-2)" "unprognostic (1.93e-1)" "unprognostic (1.73e-2)" "unprognostic (3.45e-1)" "unprognostic (6.54e-2)" "unprognostic (2.90e-1)" "unprognostic (1.36e-3)" 7.2 13.5 5.4 21.9 6.9 4.3 8.7 14.4 6.0 7.9 21.2 8.0 7.2 10.2 7.5 5.1 8.4 8.5 4.9 6.8 5.9 7.5 6.1 16.2 32.1 7.5 6.9 10.4 5.2 17.5 5.7 4.0 7.8 8.3 10.5 2.9 12.1 6.8 2.8 11.0 11.3 10.9 6.5 21.8 10.4 6.1 6.2 15.2 7.5 4.2 36.6 8.2 6.9 6.9 10.6 6.6 13.2 14.2 4.4 6.8 0.9 11.4 29.7 17.4 30.0 4.2 4.1 9.6 12.1 20.5 14.1 9.5 10.7 8.7 23.1 29.9 17.9 15.0 13.2 8.4 9.1 3.4 5.1 14.5 2.7 33.5 11.3 20.7 16.3 18.5 12.3 72.8 7.9 4.6 12.1 4.4 5.0 0.4 6.6 28.1 18.7 29.8 12.7 5.9 12.6 17.6 7.4 2.8 31.1 7.5 13.5 6.6 19.5 6.4 7.3 5.6 17.7 58.9 38.8 16.9 6.4 13.4 16.3 2.1 13.7 2.4 6.1 14.6 5.8 24.1 5.0 5.7 23.9 29.4 4.1 5.1 12.4 8.7 6.3 9.7 10.3 7.9 5.4 6.9 14.4 6.0 6.8 5.9 7.5 6.9 7.8 6.5 6.2 6.9 8.1 9.6 12.6 0.0 30.3 3.8 7.3 6.5 6.2 0.6 5.2 5.1 2.5 2.8 8.5 3.7 0.0 2.3 15.0 0.6 0.0 8.6 0.4 8.8 4.5 13.1 1.8 3.6 0.0 5.6 0.8 5.0 3.6 7.5 19.6 9.6 6.1 3.8 8.4 0.0 0.0 7.8 12.2 16.0 24.2 0.6 6.5 17.1 7.2 0.0 15.4 14.3 7.2 0.0 0.0 8.3 0.8 4.9 30.7 6.4 2.6 2.3 10.2 0.7 0.0 5.0 4.4 0.3 1.5 4.5 4.5 1.0 10.0 10.6 2.1 4.2 C10orf67 "bA215C7.4, C10orf115, LINC01552, MGC46732" ENSG00000179133 "Chromosome 10 open reading frame 67" Q8IYJ2 10 23202696-23344845 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 5.1;fallopian tube: 4.8;testis: 12.4" "Group enriched" "Detected in some" 5 "Alveolar cells type 1: 38.5;Early spermatids: 40.2;Endometrial ciliated cells: 18.2;Late spermatids: 32.8;Proximal tubular cells: 17.9;Respiratory ciliated cells: 35.7;Spermatocytes: 70.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HaCaT: 3.0;SiHa: 3.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA038131 Approved Approved Vesicles,Microtubules,Mitochondria NA No "Cluster 35: T-regs - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "Vesicles, Microtubules, Mitochondria" "HPA038131: AB_10670658" "unprognostic (4.76e-4)" "unprognostic (2.38e-1)" "unprognostic (3.75e-2)" "unprognostic (2.92e-2)" "unprognostic (9.67e-3)" "unprognostic (1.91e-1)" "unprognostic (1.54e-1)" "unprognostic (1.78e-2)" "unprognostic (8.56e-2)" "unprognostic (1.78e-1)" "unprognostic (1.24e-2)" "unprognostic (2.46e-3)" "unprognostic (3.98e-1)" "unprognostic (3.59e-2)" "unprognostic (3.84e-3)" "unprognostic (9.58e-2)" 0.0 0.2 1.5 0.2 1.4 0.3 0.1 0.9 1.6 0.1 5.1 0.1 0.5 0.2 1.4 0.1 4.8 0.2 0.7 1.7 1.3 3.5 0.4 2.9 0.3 2.0 2.2 0.5 0.2 0.4 1.2 0.1 1.5 0.0 0.0 0.9 0.1 0.1 0.5 1.3 0.3 0.0 1.3 0.2 0.1 12.4 1.9 0.0 0.6 0.1 0.1 0.0 0.0 2.0 0.7 0.1 0.9 0.1 0.0 0.2 0.3 0.1 0.0 0.9 0.8 0.2 1.3 0.1 0.1 0.8 0.1 3.0 0.1 0.3 0.8 0.3 0.2 0.3 0.7 0.2 0.5 0.1 0.2 0.2 1.0 0.3 0.4 0.1 0.0 0.1 0.3 0.5 0.0 0.3 0.1 0.2 0.5 0.0 0.1 0.1 0.1 0.1 0.7 0.2 0.5 0.2 3.9 0.1 0.0 0.1 0.2 0.2 0.2 0.2 0.8 0.2 0.1 0.5 0.1 0.0 1.1 0.1 0.2 0.1 0.0 0.1 0.1 0.0 0.1 0.2 0.3 0.2 0.0 0.3 0.2 0.2 0.0 0.2 0.1 0.2 1.2 0.0 1.5 1.4 0.9 1.6 1.7 1.3 2.0 2.2 1.5 1.3 1.9 2.0 0.0 38.5 2.4 0.3 0.0 2.8 0.1 1.9 0.0 0.4 0.0 0.0 1.8 0.0 2.5 0.0 0.0 0.0 0.0 0.0 1.9 0.2 40.2 18.2 0.2 0.1 0.0 0.0 4.7 0.2 0.0 0.2 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 32.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.5 2.2 0.2 0.0 0.7 0.0 0.0 0.0 17.9 35.7 1.6 6.6 0.0 0.1 70.1 5.2 0.0 1.3 0.0 0.3 0.5 0.1 0.0 C10orf71 FLJ45913 ENSG00000177354 "Chromosome 10 open reading frame 71" Q711Q0 10 49299170-49327492 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "skeletal muscle: 280.2;tongue: 81.9" "Cell type enriched" "Detected in some" 15 "Cardiomyocytes: 56.0" "Cancer enhanced" "Detected in single" "head and neck cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 22 "K-562: 6.9;RH-30: 9.9" "Not detected" "Not detected" HPA057556 Approved Nucleoplasm,Mitochondria NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 1: K-562 - Erythropoiesis" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm Mitochondria "HPA057556: AB_2683467" "unprognostic (1.25e-2)" "unprognostic (3.97e-2)" "unprognostic (4.16e-2)" "unprognostic (5.58e-2)" "unprognostic (1.66e-1)" "unprognostic (1.17e-1)" "unprognostic (1.81e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 44.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.3 21.9 0.0 0.0 0.1 1.3 0.0 0.0 1.2 0.0 280.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 81.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 56.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 C10orf82 "Em:AC016825.4, MGC33547" ENSG00000165863 "Chromosome 10 open reading frame 82" Q8WW14 10 116663696-116670264 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "testis: 84.5" "Group enriched" "Detected in some" 113 "Early spermatids: 1053.9;Late spermatids: 1926.7" "Cancer enhanced" "Detected in many" "breast cancer: 2.4" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 103 "basophil: 10.2" "Lineage enriched" "Detected in single" 103 "granulocytes: 10.2" "Cell line enhanced" "Detected in some" "BEWO: 1.2;Hep G2: 2.8;NTERA-2: 1.4;SuSa: 2.5;T-47d: 3.5" "Not detected" "Not detected" HPA043022 Approved Mitochondria Yes NA "Cluster 46: Basophils - DNA binding" "Cluster 83: Testis - Spermatogenesis" "Cluster 6: T47d - Mammary gland" "Cluster 34: Spermatids - Unknown function" Mitochondria "HPA043022: " "unprognostic (9.98e-2)" "unprognostic (2.09e-2)" "unprognostic (8.41e-2)" "unprognostic (2.11e-1)" "unprognostic (1.63e-2)" "unprognostic (9.52e-2)" "unprognostic (3.46e-3)" "unprognostic (3.48e-1)" "unprognostic (6.15e-2)" "unprognostic (1.50e-2)" "unprognostic (8.00e-2)" "unprognostic (1.47e-3)" "unprognostic (2.61e-2)" "unprognostic (1.94e-2)" "unprognostic (1.73e-1)" "unprognostic (1.07e-1)" 0.3 1.7 0.3 0.2 0.2 0.0 0.9 0.1 0.4 0.4 0.0 0.9 0.1 0.0 0.2 0.3 0.2 0.1 0.4 0.2 0.8 1.2 0.0 0.0 0.0 0.3 0.5 3.6 1.1 0.0 1.0 0.0 0.4 0.9 0.2 0.1 0.2 0.7 0.0 0.2 0.4 0.0 0.2 0.1 0.4 84.5 0.9 0.0 1.6 0.1 0.0 0.3 0.6 0.2 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.4 0.2 0.8 0.3 0.5 0.4 0.2 0.9 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.4 0.0 0.0 0.0 1.1 1.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1053.9 0.3 0.2 0.5 1.2 0.0 0.5 0.2 0.1 0.1 0.0 0.7 0.0 5.6 0.0 0.0 0.1 0.0 1.8 1.1 0.0 0.0 0.0 1926.7 9.0 0.6 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 5.3 0.0 0.7 0.1 0.1 0.0 0.0 13.1 0.4 0.2 10.5 8.0 0.0 0.0 0.0 0.1 8.0 1.2 0.3 C12orf65 "FLJ38663, SPG55" ENSG00000130921 "Chromosome 12 open reading frame 65" Q9H3J6 12 123233385-123258079 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein biosynthesis" RNA-binding "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 60.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057595 Approved Approved Nucleoplasm,Mitochondria,Cytosol No Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 63: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Cytosol" Mitochondria "HPA057595: " "unprognostic (9.07e-3)" "unprognostic (1.51e-2)" "unprognostic (5.30e-2)" "unprognostic (8.19e-3)" "unprognostic (1.23e-1)" "unprognostic (2.58e-1)" "prognostic unfavorable (4.29e-9)" "unprognostic (9.33e-3)" "unprognostic (2.39e-1)" "unprognostic (2.50e-2)" "unprognostic (6.33e-3)" "unprognostic (1.20e-2)" "unprognostic (2.01e-2)" "unprognostic (3.89e-2)" "unprognostic (3.19e-2)" "unprognostic (9.83e-3)" "prognostic favorable (7.82e-5)" 7.3 12.6 16.2 10.2 16.1 9.0 8.0 23.0 19.6 13.0 13.5 10.9 11.4 12.1 13.8 9.5 11.4 8.2 15.0 16.0 13.2 12.6 14.5 8.9 18.2 12.6 12.3 17.2 8.5 10.2 19.7 7.3 14.9 13.7 8.2 15.7 16.2 9.0 13.0 13.8 11.3 7.0 8.8 12.8 10.6 16.7 14.8 60.0 12.3 12.5 13.4 10.3 11.0 18.3 28.4 20.5 20.8 39.1 12.0 11.1 13.7 22.3 16.5 25.1 18.0 21.8 15.8 36.1 20.3 8.4 23.5 20.4 25.7 12.5 25.0 29.2 22.5 44.0 20.7 18.6 26.1 20.4 19.7 14.2 33.2 18.9 35.1 37.0 17.0 53.6 45.6 13.4 16.7 12.3 46.2 39.3 13.7 25.6 31.7 35.7 25.9 33.5 22.8 13.0 40.7 18.2 24.0 8.8 23.4 16.5 18.3 24.7 14.8 23.1 27.3 23.3 24.4 22.7 28.3 32.6 17.1 26.2 28.1 85.3 12.9 50.6 53.9 14.9 67.6 83.9 72.3 71.9 21.7 73.5 96.6 78.2 11.8 63.3 16.3 36.6 73.1 33.5 16.2 16.1 23.0 19.6 16.0 13.2 12.6 12.3 14.9 8.8 14.8 18.3 46.0 41.7 47.7 9.8 54.3 45.4 36.7 29.4 59.2 34.5 23.3 50.0 52.7 14.3 18.0 25.8 14.6 41.1 56.2 16.4 60.7 20.7 22.9 12.2 24.2 27.9 9.6 37.0 13.7 10.8 22.8 41.3 23.0 11.2 15.2 24.1 18.5 33.5 14.3 45.4 15.9 20.7 28.5 9.2 24.2 6.2 37.9 19.7 24.9 7.5 26.3 35.7 44.3 14.6 10.4 13.6 17.4 42.2 42.2 22.8 19.9 39.3 14.8 36.6 13.1 42.7 33.1 115.2 59.7 40.6 36.1 10.8 63.0 43.3 20.8 8.0 C12orf73 "BRAWNIN, DKFZp547P055, FLJ13975" ENSG00000204954 "Chromosome 12 open reading frame 73" Q69YU5 12 103940763-103965708 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 42.5" "Cell type enhanced" "Detected in many" "Early spermatids: 87.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038883 Uncertain Approved "Plasma membrane,Centrosome,Mitochondria" "Intracellular and membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 29: Early spermatids - Spermatogenesis" "Centrosome, Mitochondria" "Plasma membrane" "HPA038883: AB_10794735" "unprognostic (9.24e-2)" "unprognostic (3.26e-3)" "unprognostic (3.66e-3)" "unprognostic (7.20e-2)" "unprognostic (3.28e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (6.98e-4)" "unprognostic (8.96e-2)" "unprognostic (1.86e-2)" "unprognostic (3.79e-2)" "unprognostic (3.03e-3)" "unprognostic (2.07e-1)" "unprognostic (1.33e-2)" "unprognostic (1.13e-1)" "unprognostic (1.40e-2)" "unprognostic (6.27e-2)" "prognostic favorable (1.61e-4)" 6.0 11.4 15.6 7.7 15.4 4.4 7.9 17.1 16.1 8.5 13.3 7.2 7.0 8.2 10.3 6.4 7.3 4.6 12.3 15.5 16.7 10.3 8.3 5.8 9.2 14.7 15.0 10.1 7.7 10.0 10.8 6.1 15.2 8.7 7.6 13.2 7.2 7.3 42.5 8.3 6.8 6.5 14.4 6.9 8.9 10.9 15.3 8.3 12.9 27.6 8.9 7.3 6.9 17.3 11.8 21.2 31.8 19.4 8.9 11.6 20.7 12.6 7.4 13.4 10.8 23.2 9.9 13.7 15.9 7.5 11.7 18.3 19.1 15.6 10.1 19.7 38.4 20.9 32.9 29.1 13.1 30.8 18.2 10.3 17.6 6.9 11.9 32.5 12.5 39.5 27.0 9.2 12.5 13.2 34.5 46.1 15.6 11.0 35.9 19.7 11.9 13.7 17.8 16.6 51.8 18.5 13.0 21.9 29.7 14.1 36.4 16.7 6.5 16.4 9.3 12.4 12.8 24.5 40.6 28.8 22.4 17.4 14.5 10.1 5.6 10.6 11.7 5.0 11.4 14.6 10.6 11.1 8.6 11.3 15.7 14.8 1.7 14.5 4.5 13.3 17.0 4.2 15.6 15.4 17.1 16.1 15.5 16.7 14.7 15.0 15.2 14.4 15.3 17.3 6.8 6.4 6.8 7.5 7.8 6.0 9.4 16.3 18.8 16.3 9.0 11.0 16.5 7.2 10.0 9.2 0.0 11.6 8.6 7.1 27.4 20.3 87.1 8.7 10.3 8.3 11.4 18.5 5.0 12.1 11.7 7.9 15.3 9.1 9.5 13.8 8.9 15.5 17.5 8.4 6.0 13.2 20.3 7.9 5.1 36.6 8.7 8.7 1.8 2.8 12.4 17.1 22.6 7.5 9.0 19.9 5.6 8.6 13.7 13.7 16.0 25.9 10.9 15.2 6.6 5.6 11.7 31.1 25.6 16.0 5.3 8.9 8.8 6.4 12.3 8.6 C18orf63 DKFZP781G0119 ENSG00000206043 "Chromosome 18 open reading frame 63" Q68DL7 18 74315839-74359189 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 43 "testis: 9.8" "Cell type enriched" "Detected in some" 10 "Spermatocytes: 83.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA042233 Approved Mitochondria NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Mitochondria "HPA042233: AB_10960843" "unprognostic (1.40e-1)" "unprognostic (1.43e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 83.7 7.9 0.0 0.0 0.0 0.0 0.1 0.1 0.0 C1orf112 FLJ10706 ENSG00000000460 "Chromosome 1 open reading frame 112" Q9NSG2 1 169662007-169854080 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 13.5" "Cell type enhanced" "Detected in many" "Microglial cells: 30.0;Spermatocytes: 37.1;Spermatogonia: 20.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023778, HPA024451" Uncertain Approved Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Mitochondria "HPA023778: AB_1848665, HPA024451: AB_1848667" "unprognostic (4.97e-2)" "unprognostic (1.46e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (9.56e-5)" "unprognostic (1.33e-1)" "unprognostic (9.40e-2)" "unprognostic (2.50e-3)" "unprognostic (2.09e-1)" "unprognostic (9.11e-3)" "unprognostic (8.79e-2)" "unprognostic (3.47e-3)" "unprognostic (5.97e-2)" "unprognostic (1.65e-8)" "unprognostic (1.76e-1)" "unprognostic (2.81e-2)" "unprognostic (6.17e-2)" "unprognostic (2.63e-1)" 1.8 1.2 0.6 3.3 0.9 9.0 2.9 1.7 0.8 2.3 0.5 2.6 1.2 2.9 1.0 2.0 1.5 1.4 1.0 0.5 0.4 1.1 2.6 1.7 6.3 1.0 0.6 2.2 1.5 13.5 1.0 3.4 0.8 1.8 4.1 5.4 1.5 2.0 0.9 2.4 1.8 2.7 0.7 2.8 1.9 10.3 0.9 11.6 1.7 1.5 7.9 3.1 1.7 1.5 32.7 17.5 21.9 11.3 3.5 4.8 32.2 21.1 10.7 30.0 30.6 19.1 27.7 29.0 9.3 7.0 10.7 26.0 27.6 14.7 34.3 16.9 16.5 27.1 23.0 14.1 1.2 35.8 11.3 1.5 1.9 22.5 5.3 3.5 12.8 16.8 44.9 48.0 24.8 7.9 31.5 10.3 28.8 22.9 12.1 23.3 24.7 19.5 4.0 16.1 16.2 16.9 13.4 22.1 6.9 20.6 21.0 18.3 9.5 24.1 19.1 17.8 28.9 12.9 20.9 30.6 9.0 26.4 24.1 2.2 0.8 1.0 0.6 1.9 0.4 1.4 0.6 0.6 1.2 1.4 0.3 0.5 0.1 2.1 2.3 0.4 0.7 0.6 0.6 0.9 1.7 0.8 0.5 0.4 1.0 0.6 0.8 0.7 0.9 1.5 1.2 0.0 3.3 4.2 4.0 1.8 2.7 2.6 1.2 4.1 1.7 1.8 0.5 0.0 1.5 0.0 6.2 9.1 1.6 1.9 0.0 2.7 8.7 0.9 2.1 2.2 0.0 3.4 9.9 3.4 9.1 2.5 2.6 1.2 4.5 9.8 2.9 3.8 6.2 1.7 9.6 1.2 6.1 3.5 2.1 4.1 2.1 3.0 3.6 30.0 1.3 2.4 0.0 13.0 13.2 3.0 0.3 3.8 5.5 1.0 0.8 0.7 2.0 6.6 6.6 1.4 2.6 37.1 20.3 2.8 1.0 3.8 3.3 2.2 2.6 2.4 C1QBP "gC1Q-R, gC1qR, HABP1, p32, SF2p32" ENSG00000108561 "Complement C1q binding protein" Q07021 17 5432777-5448830 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Adaptive immunity, Apoptosis, Complement pathway, Host-virus interaction, Immunity, Innate immunity, mRNA processing, mRNA splicing, Ribosome biogenesis, Transcription, Transcription regulation" "Cancer-related genes, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026483 Supported Approved "Plasma membrane,Mitochondria" "Secreted to blood" NA NA 410000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane" Mitochondria "HPA026483: AB_1847108" "unprognostic (2.18e-1)" "unprognostic (1.74e-1)" "unprognostic (3.80e-2)" "unprognostic (6.40e-2)" "unprognostic (2.60e-1)" "unprognostic (6.76e-2)" "unprognostic (7.47e-2)" "unprognostic (4.62e-2)" "unprognostic (2.40e-3)" "unprognostic (6.03e-2)" "unprognostic (4.60e-3)" "unprognostic (3.08e-2)" "unprognostic (7.80e-3)" "unprognostic (1.20e-1)" "unprognostic (3.13e-1)" "unprognostic (3.28e-1)" "unprognostic (3.97e-1)" 79.3 135.4 85.5 84.1 85.7 121.2 108.7 91.5 118.3 58.4 119.6 140.3 95.9 66.4 68.3 138.6 74.5 48.7 126.3 89.5 94.3 136.4 134.5 54.7 115.7 89.6 92.3 52.7 72.9 127.7 81.3 75.8 93.2 63.9 141.6 86.7 66.2 73.1 174.2 81.3 78.4 80.9 93.1 73.5 74.3 62.5 90.7 98.5 65.1 160.1 135.6 108.4 73.9 97.3 443.8 671.0 233.0 378.0 169.8 207.7 313.7 330.4 268.5 751.4 458.8 646.8 143.7 941.8 317.8 251.3 271.3 385.8 756.7 448.9 689.8 216.6 1300.5 433.9 312.4 762.2 269.9 535.6 331.0 231.4 404.1 414.6 593.1 181.1 390.0 548.2 526.1 234.4 296.1 308.6 766.4 385.6 525.9 497.2 396.7 601.2 329.1 515.0 440.5 328.7 186.0 348.0 271.4 344.4 483.6 232.1 218.1 267.1 231.1 240.1 219.7 275.9 729.9 122.0 201.2 415.0 229.3 506.2 376.8 68.1 197.6 49.9 217.1 212.0 283.5 330.1 239.0 215.4 389.5 289.8 289.7 245.7 15.5 240.7 166.4 325.4 203.6 432.6 85.5 85.7 91.5 118.3 89.5 94.3 89.6 92.3 93.2 93.1 90.7 97.3 101.6 28.9 30.5 10.7 153.1 243.1 229.0 283.3 165.0 70.5 157.3 209.4 84.8 102.9 107.8 82.8 27.1 323.8 115.0 105.6 313.1 248.0 75.1 106.7 149.9 108.2 79.2 183.1 10.8 205.1 457.9 101.0 94.8 85.9 62.2 131.6 75.3 128.5 202.7 60.6 11.6 190.2 154.6 85.3 129.8 89.5 119.6 101.8 156.5 10.3 170.3 105.2 93.7 11.1 16.1 199.3 128.5 98.6 197.4 255.1 78.9 444.1 65.1 79.9 85.5 101.6 189.1 79.3 237.3 284.4 255.3 179.0 105.5 354.3 364.0 253.8 C2orf49 "asw, MGC5509" ENSG00000135974 "Chromosome 2 open reading frame 49" Q9BVC5 2 105337532-105349211 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043846, HPA060814" Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm Mitochondria "HPA043846: AB_2678698, HPA060814: AB_2684372" "unprognostic (4.19e-2)" "unprognostic (1.49e-1)" "unprognostic (3.06e-1)" "unprognostic (6.16e-3)" "unprognostic (2.57e-3)" "unprognostic (8.75e-3)" "unprognostic (1.89e-3)" "unprognostic (6.51e-2)" "unprognostic (5.01e-2)" "unprognostic (2.07e-1)" "unprognostic (2.56e-1)" "unprognostic (5.94e-2)" "prognostic unfavorable (5.06e-5)" "unprognostic (1.22e-1)" "unprognostic (1.22e-1)" "unprognostic (1.39e-1)" "unprognostic (6.04e-2)" 11.3 9.3 9.6 10.6 11.9 19.3 11.1 12.0 12.9 12.5 6.2 9.1 9.4 14.6 7.8 11.8 12.4 9.5 15.3 8.9 10.7 8.7 10.1 8.6 12.6 11.2 11.5 19.9 11.0 10.5 5.5 12.0 11.3 11.3 9.9 24.9 9.1 11.0 19.9 9.5 10.1 12.2 10.2 11.1 13.8 13.0 10.6 16.0 12.6 21.0 13.3 11.3 10.5 13.8 20.0 13.9 17.2 17.5 19.4 23.6 30.7 19.6 20.6 17.0 23.3 30.7 19.5 23.3 23.9 17.1 45.6 18.7 23.9 16.7 22.2 30.6 18.1 25.3 11.6 23.8 23.6 21.3 20.1 17.1 28.7 24.0 21.6 24.3 15.8 18.1 35.9 18.7 24.3 15.4 25.9 24.5 22.6 13.5 16.8 17.1 25.4 27.1 19.2 18.9 20.3 16.2 17.3 15.5 23.8 19.2 15.2 23.8 25.4 17.9 25.1 13.0 16.1 23.6 20.5 24.6 18.1 21.3 17.6 15.4 13.2 12.0 9.0 8.3 8.9 14.5 10.1 9.0 9.2 17.6 11.0 9.3 17.8 9.2 11.9 19.1 12.7 6.7 9.6 11.9 12.0 12.9 8.9 10.7 11.2 11.5 11.3 10.2 10.6 13.8 27.0 16.0 14.3 7.5 26.3 29.1 13.4 21.8 15.4 37.1 24.8 22.9 30.9 18.6 22.0 25.8 29.2 21.2 31.6 16.5 25.4 22.9 40.6 43.1 34.7 19.3 11.3 21.2 10.8 18.2 26.5 22.8 12.8 33.9 16.5 18.1 19.6 22.4 16.1 23.5 11.2 22.5 12.2 18.5 13.5 35.8 27.7 15.5 7.2 10.3 21.1 39.6 28.8 7.1 15.8 21.0 17.5 29.0 19.0 16.2 21.8 22.3 36.1 44.3 19.7 17.3 19.8 45.8 28.1 13.7 24.7 36.8 22.4 16.6 14.8 15.8 C2orf68 ENSG00000168887 "Chromosome 2 open reading frame 68" Q2NKX9 2 85605254-85612066 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051143 Uncertain Approved "Nucleoplasm,Nuclear membrane,Nucleoli,Mitochondria" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nuclear membrane, Mitochondria" Nucleoli "HPA051143: AB_2681360" "unprognostic (1.71e-2)" "unprognostic (3.65e-2)" "unprognostic (1.07e-2)" "prognostic unfavorable (1.12e-6)" "unprognostic (9.34e-2)" "unprognostic (2.16e-1)" "prognostic unfavorable (6.76e-6)" "unprognostic (4.24e-3)" "unprognostic (8.41e-2)" "unprognostic (2.34e-1)" "unprognostic (2.88e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (1.11e-6)" "unprognostic (1.18e-1)" "unprognostic (1.76e-1)" "unprognostic (3.70e-2)" "unprognostic (8.81e-3)" 11.0 9.4 8.8 10.0 11.6 10.5 12.6 15.4 9.9 18.7 10.7 13.6 11.0 15.7 12.2 12.1 15.2 6.6 12.3 8.6 9.4 12.8 11.7 14.0 14.2 11.7 10.8 20.4 17.2 8.5 14.0 12.5 11.0 16.4 10.9 20.0 16.4 10.7 21.8 16.3 16.6 9.9 9.8 16.9 14.3 9.5 10.2 13.7 16.3 9.8 13.9 13.6 15.4 15.2 8.8 7.9 15.7 11.5 14.2 7.6 10.2 4.3 5.6 6.7 8.7 7.1 10.6 12.4 6.0 7.3 6.0 10.4 7.9 7.5 7.2 6.8 19.1 21.1 13.8 8.5 11.2 12.3 11.4 11.3 9.7 4.4 12.7 10.6 10.1 14.7 10.7 12.4 6.3 9.3 13.3 13.4 6.9 10.2 7.3 14.8 27.8 11.5 8.5 10.1 19.8 14.2 6.5 8.5 9.0 8.7 9.1 6.5 7.0 4.8 12.8 5.9 4.2 17.9 11.8 10.8 7.2 12.9 6.0 32.7 30.5 59.0 22.4 21.8 21.3 14.6 21.1 21.0 22.4 20.7 30.5 28.2 49.2 31.2 27.0 15.2 17.7 16.7 8.8 11.6 15.4 9.9 8.6 9.4 11.7 10.8 11.0 9.8 10.2 15.2 8.2 64.1 63.1 15.0 18.6 5.9 18.2 10.0 9.6 17.4 16.0 12.3 10.7 37.1 24.3 35.0 35.5 47.2 24.4 24.6 17.6 17.9 4.8 9.4 8.7 13.9 19.2 19.5 2.7 19.8 17.7 12.9 17.9 9.6 34.7 15.6 17.9 25.3 23.3 25.2 6.8 16.9 12.2 34.9 14.3 12.8 24.2 26.0 14.2 15.0 31.4 12.3 38.1 10.1 16.9 19.4 14.0 13.5 13.6 14.4 32.7 26.6 21.0 27.0 19.7 13.7 8.5 37.2 20.1 27.4 9.8 24.9 18.1 10.0 15.8 19.2 C5orf46 "MGC23985, SSSP1" ENSG00000178776 "Chromosome 5 open reading frame 46" Q6UWT4 5 147880726-147906538 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "salivary gland: 181.8;skin 1: 113.1" "Group enriched" "Detected in some" 12 "Early spermatids: 320.9;Late spermatids: 189.9" "Cancer enhanced" "Detected in many" "renal cancer: 8.3" "Region enriched" "Detected in single" 10 "cerebellum: 2.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 54.2;PC-3: 90.8;SiHa: 20.2;U-2 OS: 58.2;U-251 MG: 23.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA058999, HPA079692" Supported Approved "Nuclear speckles,Mitochondria" "Secreted in other tissues" NA NA 54000 "Cluster 31: Skin - Epidermis development" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nuclear speckles" Mitochondria "HPA058999: , HPA079692: " "unprognostic (1.72e-1)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.26e-4)" "unprognostic (9.75e-3)" "unprognostic (2.95e-3)" "unprognostic (1.69e-3)" "unprognostic (1.99e-2)" "unprognostic (3.08e-2)" "unprognostic (2.22e-1)" "unprognostic (4.96e-2)" "unprognostic (2.86e-3)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.75e-9)" "unprognostic (6.48e-3)" "unprognostic (3.47e-2)" "unprognostic (6.01e-2)" "unprognostic (2.79e-2)" 0.4 0.0 0.0 0.0 0.0 0.0 13.5 2.3 0.1 1.6 0.7 0.4 0.0 0.1 0.4 0.4 0.0 0.2 9.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 2.2 0.2 0.9 0.0 0.6 181.8 0.1 0.8 113.1 0.0 3.2 0.0 0.0 0.0 19.2 0.0 0.3 0.2 0.1 0.3 0.0 3.6 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.0 2.4 1.4 0.0 0.0 0.4 0.0 0.0 0.1 0.0 1.0 0.3 0.0 0.6 0.0 0.2 0.2 0.0 4.6 0.2 0.0 0.0 0.0 0.0 1.1 0.0 8.9 54.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 90.8 0.0 0.5 0.0 0.0 0.1 0.0 0.0 20.2 0.3 0.3 11.1 0.0 0.0 0.0 10.0 58.2 0.8 23.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.8 0.0 0.0 9.2 3.7 11.0 15.7 0.2 1.8 0.0 0.5 0.2 0.0 0.0 15.9 320.9 0.7 0.4 0.3 0.0 0.0 0.0 3.3 0.6 0.2 0.0 3.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 189.9 1.8 0.2 3.6 0.0 0.6 7.7 0.0 0.0 0.0 4.2 0.0 0.4 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.0 2.1 1.1 0.8 0.0 20.6 1.4 0.1 0.0 0.0 0.2 C5orf63 "FLJ44606, YDR286C" ENSG00000164241 "Chromosome 5 open reading frame 63" A6NC05 5 127042558-127073492 "Predicted intracellular proteins" "Electron transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in all" 43 "brain: 760.0;choroid plexus: 360.8" "Cell type enhanced" "Detected in many" "Spermatocytes: 49.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-87 MG: 49.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043240 Approved Approved Mitochondria NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Mitochondria "HPA043240: AB_10962511" "unprognostic (2.71e-1)" "unprognostic (3.97e-2)" "unprognostic (1.11e-1)" "unprognostic (2.63e-1)" "unprognostic (1.62e-1)" "unprognostic (1.93e-1)" "unprognostic (2.94e-4)" "unprognostic (1.34e-1)" "unprognostic (9.67e-2)" "unprognostic (3.40e-2)" "unprognostic (1.43e-4)" "unprognostic (1.07e-1)" "unprognostic (2.26e-2)" "unprognostic (1.21e-1)" "unprognostic (1.32e-1)" "unprognostic (3.64e-3)" "unprognostic (1.07e-2)" 3.3 3.7 412.4 4.3 388.9 4.0 6.5 381.5 760.0 2.6 360.8 7.7 6.4 5.3 4.2 5.5 4.6 4.2 6.9 415.7 402.6 6.0 5.3 4.1 8.2 430.5 432.1 3.7 5.3 6.7 6.9 3.3 445.4 5.5 11.9 13.1 4.6 4.1 5.0 4.0 7.0 3.6 371.7 4.2 7.7 12.8 391.3 5.9 8.8 6.4 8.3 4.8 2.8 416.6 0.9 4.0 1.1 2.3 2.9 4.6 0.6 4.2 0.5 5.2 3.0 9.8 12.2 0.0 17.1 3.4 7.5 1.5 7.3 4.6 7.4 1.6 6.2 10.1 15.6 11.9 7.2 6.0 0.5 4.6 11.6 6.6 3.4 3.6 4.5 4.2 0.7 1.8 5.1 8.1 0.2 5.5 0.7 8.4 3.0 4.4 2.5 7.0 5.8 6.0 9.8 8.0 5.5 2.5 0.3 2.1 10.1 8.8 3.5 10.8 10.0 12.5 2.7 6.0 16.5 0.4 49.8 0.8 5.7 5.8 0.4 5.0 7.5 1.7 6.2 15.4 6.9 8.3 3.7 14.2 10.1 7.7 1.6 15.7 0.4 12.2 12.5 3.4 412.4 388.9 381.5 760.0 415.7 402.6 430.5 432.1 445.4 371.7 391.3 416.6 2.9 6.4 11.7 18.9 11.3 1.0 11.3 19.9 8.6 11.9 6.9 4.2 33.7 4.3 8.6 16.5 14.6 10.1 12.5 14.6 19.6 16.8 30.2 7.5 1.0 4.6 10.8 9.9 4.3 10.2 9.2 4.3 12.2 5.6 10.1 7.1 3.9 10.0 5.4 0.0 6.7 11.7 10.2 1.0 1.9 17.5 2.5 1.6 8.8 15.9 1.8 11.7 19.6 11.1 1.2 12.4 17.2 2.2 6.1 6.2 10.5 5.8 13.2 10.6 6.6 4.6 2.7 49.8 19.3 11.9 1.1 2.7 6.6 8.2 13.7 11.7 C9orf131 MGC41945 ENSG00000174038 "Chromosome 9 open reading frame 131" Q5VYM1 9 35041095-35045986 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 35.8" "Group enriched" "Detected in some" 18 "Early spermatids: 129.6;Late spermatids: 35.7" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 6.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "RT4: 9.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA022029 Approved Mitochondria NA NA "Cluster 46: Basophils - DNA binding" "Cluster 78: Testis - Spermatogenesis" "Cluster 15: RT4 - Unknown function" "Cluster 23: Spermatids - Flagellum & Golgi organization" Mitochondria "HPA022029: AB_10960628" "unprognostic (1.10e-2)" "unprognostic (8.99e-2)" "unprognostic (2.06e-1)" "unprognostic (1.31e-1)" "unprognostic (1.91e-1)" "unprognostic (1.23e-3)" "unprognostic (2.47e-1)" "unprognostic (6.57e-2)" "unprognostic (3.66e-1)" "unprognostic (9.45e-2)" "unprognostic (4.63e-2)" "unprognostic (1.75e-2)" "unprognostic (2.37e-2)" "unprognostic (9.34e-2)" "unprognostic (1.82e-1)" "unprognostic (9.90e-4)" "unprognostic (4.19e-3)" 0.3 0.2 0.8 0.5 0.8 2.6 0.7 6.3 2.2 1.3 0.3 0.6 0.3 2.7 1.3 0.2 0.1 2.1 0.4 1.3 1.0 0.4 0.7 0.2 0.8 0.8 0.1 0.2 0.2 0.4 0.1 0.5 0.8 0.2 0.7 1.4 0.1 0.1 1.3 1.1 0.3 0.2 0.0 0.5 0.4 35.8 1.1 0.1 0.7 0.0 0.2 0.5 0.0 1.8 2.0 0.3 0.2 0.1 0.4 0.0 0.8 0.4 0.0 0.0 0.0 0.6 1.2 0.4 0.2 0.0 0.7 1.4 0.0 0.0 0.2 0.3 0.3 0.8 2.0 0.5 0.0 0.3 0.7 0.0 0.3 0.0 0.0 0.0 0.3 0.7 1.8 1.6 0.0 0.4 0.3 0.8 0.4 0.5 0.0 0.0 0.2 0.0 0.2 9.1 0.2 0.0 0.5 0.0 0.3 0.3 0.5 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.4 0.8 0.0 0.1 0.8 0.5 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.8 0.8 6.3 2.2 1.3 1.0 0.8 0.1 0.8 0.0 1.1 1.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 129.6 0.5 0.5 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.0 0.0 35.7 1.5 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.3 0.0 4.4 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 CACNA1B "CACNL1A5, CACNN, Cav2.2" ENSG00000148408 "Calcium voltage-gated channel subunit alpha1 B" Q00975 9 137877782-138124624 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.2;pituitary gland: 6.8;testis: 5.1" "Group enriched" "Detected in some" 8 "Excitatory neurons: 388.8;Inhibitory neurons: 330.9" "Cancer enhanced" "Detected in some" "testis cancer: 2.2" "Group enriched" "Detected in many" 8 "amygdala: 5.9;basal ganglia: 7.8;cerebral cortex: 10.2;hippocampal formation: 3.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SCLC-21H: 19.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022919, HPA044347" Uncertain Approved Mitochondria NA NA "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Mitochondria "HPA022919: , HPA044347: AB_10960837" "unprognostic (1.34e-3)" "unprognostic (2.70e-2)" "unprognostic (8.08e-2)" "unprognostic (2.51e-7)" "unprognostic (8.10e-2)" "unprognostic (1.51e-2)" "unprognostic (1.33e-1)" "unprognostic (3.10e-1)" "unprognostic (2.50e-1)" "unprognostic (2.36e-2)" "unprognostic (9.73e-4)" "unprognostic (5.98e-2)" "unprognostic (6.63e-6)" "unprognostic (4.25e-2)" "unprognostic (4.72e-1)" "unprognostic (7.77e-3)" "unprognostic (8.69e-2)" 0.0 2.8 5.9 0.1 7.8 0.0 0.0 0.8 10.2 0.3 0.0 0.4 0.0 0.0 0.6 0.0 3.1 0.4 0.3 3.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.8 6.8 0.0 0.0 0.5 0.1 3.5 0.0 0.4 0.0 0.2 0.2 0.1 0.0 0.0 0.3 5.1 0.0 1.2 0.2 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.5 3.7 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 7.8 0.8 10.2 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 43.4 0.0 0.0 0.1 0.0 0.0 11.7 0.2 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 3.4 0.0 0.2 0.1 0.0 0.0 388.8 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 6.7 330.9 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 17.8 0.6 1.7 0.0 16.1 10.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.2 8.2 9.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 CALHM2 FAM26B ENSG00000138172 "Calcium homeostasis modulator family member 2" Q9HA72 10 103446786-103452402 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 75.1;Fibroblasts: 38.2;Hepatic stellate cells: 48.2;Hofbauer cells: 53.7;Leydig cells: 45.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 45.1;BJ: 37.7;BJ hTERT+: 37.5;fHDF/TERT166: 43.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA014706 Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Mitochondria" Cytosol "HPA014706: AB_2243916" "unprognostic (2.45e-1)" "unprognostic (1.16e-1)" "unprognostic (3.01e-1)" "unprognostic (2.48e-1)" "unprognostic (3.92e-2)" "unprognostic (1.77e-1)" "unprognostic (1.10e-1)" "unprognostic (1.63e-1)" "unprognostic (8.85e-2)" "unprognostic (5.78e-2)" "unprognostic (1.19e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (3.03e-6)" "unprognostic (8.59e-2)" "unprognostic (2.47e-1)" "unprognostic (3.56e-1)" "unprognostic (4.74e-1)" 49.7 18.5 7.2 12.5 6.5 2.1 38.9 6.3 9.0 54.4 7.0 18.4 6.5 58.1 5.5 12.2 43.3 21.6 34.2 7.0 7.3 10.7 4.5 23.2 13.7 8.0 6.4 48.1 7.1 3.1 7.3 10.0 7.8 21.1 4.3 0.4 14.9 10.6 9.7 17.9 19.6 15.9 7.7 35.3 13.8 11.5 8.0 5.6 21.6 11.1 6.1 33.9 39.3 7.9 11.0 7.5 1.8 2.4 27.3 45.1 9.1 37.7 37.5 11.2 15.7 3.3 5.3 3.3 4.2 43.2 0.7 5.0 3.8 0.0 2.1 0.4 21.5 7.8 2.5 0.6 12.4 1.3 0.7 15.6 0.0 3.3 0.1 20.8 13.5 8.3 1.8 19.8 7.5 25.0 3.0 3.7 4.8 2.3 6.7 9.2 3.0 7.5 1.0 0.9 5.3 2.3 1.5 6.2 2.1 0.8 1.2 2.5 24.5 3.6 4.4 12.6 2.7 3.0 7.6 3.8 31.0 24.0 0.8 70.0 91.9 1.8 83.7 178.4 69.6 27.7 56.5 69.7 152.1 7.3 10.8 42.3 3.6 62.9 214.6 17.8 82.7 85.6 7.2 6.5 6.3 9.0 7.0 7.3 8.0 6.4 7.8 7.7 8.0 7.9 18.2 3.2 0.6 1.0 4.9 5.4 2.9 0.6 4.0 0.1 3.4 4.4 3.3 1.5 0.0 3.7 0.0 3.1 11.3 0.1 0.0 4.2 1.0 1.4 19.8 25.5 1.2 5.7 2.3 0.2 75.1 38.2 1.5 2.1 8.8 11.4 48.2 0.6 53.7 0.0 0.5 0.1 2.0 28.8 18.8 2.5 45.7 21.5 8.8 2.8 17.3 0.2 33.0 1.0 0.2 0.1 0.1 16.1 3.1 0.8 0.0 0.3 0.0 0.1 19.7 16.8 27.9 0.8 0.9 0.8 3.8 19.2 19.4 6.0 0.0 1.0 CARS2 FLJ12118 ENSG00000134905 "Cysteinyl-tRNA synthetase 2, mitochondrial" Q9HA77 13 110641412-110713603 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 221.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "U-87 MG: 204.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041776 Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Mitochondria" "HPA041776: AB_2677666" "unprognostic (2.34e-3)" "unprognostic (9.50e-2)" "unprognostic (6.62e-2)" "prognostic favorable (1.84e-4)" "unprognostic (1.98e-1)" "unprognostic (3.54e-3)" "prognostic unfavorable (1.21e-4)" "unprognostic (1.90e-1)" "unprognostic (1.08e-1)" "unprognostic (7.82e-2)" "unprognostic (2.11e-3)" "unprognostic (5.75e-2)" "prognostic unfavorable (2.49e-5)" "unprognostic (4.73e-2)" "unprognostic (3.42e-1)" "unprognostic (3.21e-1)" "unprognostic (1.71e-2)" 18.3 24.4 8.8 18.9 9.3 28.4 15.0 16.3 13.3 20.3 15.8 20.8 17.5 16.0 13.7 18.6 16.4 11.1 25.9 9.7 9.3 15.4 19.9 16.7 19.3 9.0 9.3 15.3 15.8 15.0 17.6 12.1 9.7 15.2 13.8 9.2 18.9 12.3 45.8 17.6 18.5 12.6 9.2 17.8 17.2 11.2 9.7 12.9 14.3 26.7 14.1 17.7 15.9 10.5 116.0 37.7 21.2 52.6 55.7 51.7 28.7 49.9 45.7 49.6 60.6 53.5 50.7 53.5 68.4 55.4 75.6 61.0 36.6 63.8 40.2 49.2 58.5 33.5 79.6 63.8 58.5 83.0 39.3 66.7 50.7 43.3 51.8 35.5 36.0 40.9 23.2 16.6 71.2 27.2 37.5 27.6 18.4 88.9 36.8 54.2 15.6 22.3 54.2 33.4 37.7 28.9 40.7 62.0 61.1 22.7 29.8 94.0 32.5 41.8 15.6 53.2 51.6 29.0 35.8 32.4 204.5 50.1 41.9 0.0 2.9 0.4 1.1 3.3 1.2 1.8 0.3 0.4 2.4 0.8 1.1 0.5 1.7 0.4 4.6 2.0 0.4 1.1 8.8 9.3 16.3 13.3 9.7 9.3 9.0 9.3 9.7 9.2 9.7 10.5 18.2 9.6 15.9 24.5 24.4 12.9 24.2 10.3 8.6 21.4 21.8 23.4 39.3 18.6 9.5 27.6 25.0 26.7 28.2 17.6 50.9 17.7 66.5 24.1 21.7 13.6 18.7 10.7 29.2 4.7 29.1 21.6 18.8 27.3 16.5 45.3 9.3 26.6 26.9 23.5 25.1 17.7 12.2 31.2 9.0 221.4 20.5 32.8 12.4 24.4 51.4 24.3 14.4 14.1 26.6 12.1 10.8 18.0 18.6 18.2 23.0 38.1 10.6 25.9 6.6 29.2 24.7 8.6 7.5 22.3 13.5 16.8 19.8 44.2 28.5 17.6 CASP14 "MGC119078, MGC119079, MICE" ENSG00000105141 "Caspase 14" P31944 19 15049480-15058293 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Differentiation "Hydrolase, Protease, Thiol protease" Ichthyosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "skin 1: 486.0" "Cell type enriched" "Detected in some" 5 "Suprabasal keratinocytes: 96.0" "Cancer enhanced" "Detected in many" "cervical cancer: 62.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "hTCEpi: 49.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB010059, HPA027062" Enhanced Supported Nucleoplasm,Mitochondria,Cytosol NA NA 3600000 "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "Nucleoplasm, Cytosol" Mitochondria "CAB010059: AB_626800, HPA027062: AB_2672101" "unprognostic (1.17e-2)" "unprognostic (6.44e-3)" "unprognostic (6.22e-2)" "unprognostic (2.77e-1)" "prognostic unfavorable (7.59e-4)" "unprognostic (9.42e-2)" "unprognostic (2.19e-2)" "prognostic unfavorable (5.96e-4)" "unprognostic (2.68e-1)" "unprognostic (4.30e-2)" "unprognostic (1.99e-1)" "unprognostic (1.97e-1)" 0.6 0.0 0.1 0.0 0.4 0.4 7.8 0.4 0.2 3.9 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.3 0.1 0.0 0.6 0.1 0.0 0.0 0.3 0.8 0.0 0.1 1.1 4.2 1.4 486.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 1.0 0.0 0.0 0.0 0.0 19.9 1.0 1.1 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.9 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.4 0.2 0.2 0.1 0.3 0.1 0.3 0.0 0.3 1.0 0.0 0.0 0.0 0.0 0.0 19.1 1.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.4 2.8 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 96.0 0.7 0.1 0.0 0.0 0.8 CASP3 "apopain, CPP32, CPP32B, Yama" ENSG00000164305 "Caspase 3" P42574 4 184627696-184649509 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 118.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "basophil: 571.0;eosinophil: 408.6" "Lineage enriched" "Detected in all" 8 "granulocytes: 571.0" "Cell line enhanced" "Detected in all" "Karpas-707: 259.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000091, HPA002643, CAB008381" Enhanced Approved Nucleoplasm,Mitochondria NA NA 94000 "Cluster 2: Granulocytes - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Mitochondria Nucleoplasm "CAB000091: , CAB008381: AB_590737, HPA002643: AB_1846048" "unprognostic (1.38e-1)" "unprognostic (1.06e-1)" "unprognostic (2.21e-2)" "prognostic favorable (2.24e-4)" "unprognostic (2.29e-3)" "unprognostic (3.58e-2)" "unprognostic (9.57e-3)" "unprognostic (5.86e-2)" "unprognostic (3.56e-2)" "unprognostic (1.12e-2)" "unprognostic (1.70e-2)" "unprognostic (2.41e-1)" "prognostic unfavorable (2.30e-5)" "unprognostic (1.41e-2)" "unprognostic (5.74e-3)" "unprognostic (1.30e-1)" "unprognostic (4.05e-3)" 16.3 12.1 11.3 26.6 10.9 32.8 16.3 18.6 11.4 12.7 10.0 34.2 54.1 12.7 12.9 27.7 9.2 19.9 14.7 10.8 12.2 8.5 22.0 12.8 43.4 10.8 11.5 8.9 13.4 9.0 8.8 26.1 11.4 11.3 33.9 12.7 13.2 10.6 13.9 16.1 41.8 15.3 11.6 23.0 31.2 9.3 11.3 39.0 10.6 14.1 41.9 24.4 12.0 13.0 31.0 16.7 65.3 31.6 39.4 52.2 37.6 90.2 67.7 61.9 35.4 30.7 25.2 42.4 13.9 44.1 29.2 25.5 52.1 32.1 69.7 109.9 28.7 68.2 12.9 71.4 47.3 55.9 62.3 71.7 38.3 39.3 31.4 44.4 77.6 43.1 57.2 259.8 64.5 13.2 89.1 51.8 65.1 33.7 20.9 63.6 30.8 41.2 52.9 49.3 37.1 40.5 39.1 35.1 52.1 64.3 19.2 35.9 54.1 28.2 25.9 21.1 42.4 118.9 121.6 29.2 34.2 38.5 40.9 571.0 26.1 408.6 32.1 43.3 34.4 26.0 29.5 46.3 33.3 18.6 22.2 32.8 35.6 62.0 71.0 26.5 64.1 47.5 11.3 10.9 18.6 11.4 10.8 12.2 10.8 11.5 11.4 11.6 11.3 13.0 28.6 19.2 15.8 26.4 32.3 48.7 22.2 34.1 35.9 18.6 21.7 17.0 17.5 5.7 36.3 12.9 0.0 46.9 54.8 37.4 13.7 18.4 9.6 24.9 17.1 26.6 18.0 62.3 9.6 23.7 33.6 19.5 24.5 24.9 17.7 24.8 21.0 15.3 23.9 13.5 12.6 37.6 44.7 27.0 17.4 4.0 7.5 33.3 30.2 13.1 41.5 15.4 37.0 11.1 18.4 25.0 18.8 7.5 118.6 20.1 26.6 8.4 30.4 11.3 13.1 19.0 20.8 7.9 16.4 34.6 28.6 51.4 43.8 23.1 24.4 36.7 CASP9 "APAF-3, ICE-LAP6, MCH6, PPP1R56" ENSG00000132906 "Caspase 9" P55211 1 15490832-15526534 "Cancer-related genes, Enzymes, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 35.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001473, CAB004348, HPA046488" Approved Approved Mitochondria NA NA "Cluster 46: Basophils - DNA binding" "Cluster 35: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 41: Macrophages - Immune response" Mitochondria "CAB004348: AB_673489, HPA001473: AB_1078401, HPA046488: AB_2679670" "prognostic favorable (5.91e-4)" "unprognostic (2.42e-1)" "unprognostic (8.94e-3)" "unprognostic (7.84e-2)" "unprognostic (1.93e-2)" "unprognostic (8.54e-3)" "unprognostic (1.90e-3)" "unprognostic (6.75e-2)" "unprognostic (2.58e-1)" "unprognostic (1.29e-1)" "unprognostic (9.09e-2)" "unprognostic (1.98e-1)" "unprognostic (1.39e-2)" "unprognostic (2.35e-1)" "unprognostic (3.21e-2)" "unprognostic (5.48e-2)" "prognostic favorable (1.67e-5)" 12.0 50.8 14.1 7.0 14.5 11.5 8.9 16.1 18.8 19.3 13.3 11.8 6.4 14.4 12.5 14.1 22.5 9.4 16.4 14.2 13.0 20.7 14.8 10.8 6.9 14.8 14.2 57.6 37.8 12.0 32.4 7.1 14.1 19.2 5.3 12.3 8.9 9.8 12.7 5.5 11.0 6.6 13.6 10.6 12.4 25.9 14.6 8.7 25.9 9.4 7.9 12.9 12.8 17.1 10.4 17.8 4.6 8.9 11.0 5.4 5.3 7.5 9.9 11.1 12.7 12.5 10.1 13.4 16.2 7.5 13.1 4.2 10.5 8.2 11.7 5.9 11.6 9.8 32.8 10.8 10.8 10.6 11.5 9.7 11.5 15.3 3.8 8.3 8.7 13.3 20.4 13.4 5.8 5.2 3.3 8.6 5.9 11.3 8.2 7.4 13.4 16.4 12.3 6.7 4.4 9.0 9.6 1.8 15.6 12.1 5.7 7.9 4.8 13.8 5.8 15.6 5.1 13.3 21.5 16.3 8.9 9.9 5.0 54.2 24.7 54.8 11.0 17.4 8.2 21.3 6.6 7.6 25.1 30.0 3.1 4.8 36.3 29.3 18.9 11.4 6.9 15.0 14.1 14.5 16.1 18.8 14.2 13.0 14.8 14.2 14.1 13.6 14.6 17.1 2.8 3.2 3.7 18.3 17.1 2.9 8.2 5.0 4.6 3.2 7.0 4.7 9.3 11.5 7.3 18.4 6.2 17.0 8.0 7.0 1.9 7.5 12.6 10.9 5.2 3.3 3.0 5.7 7.9 9.1 10.8 5.6 12.8 7.6 1.3 5.7 4.2 4.7 9.5 5.0 9.9 6.3 6.1 4.8 12.9 5.5 2.1 12.9 0.0 6.5 4.8 7.5 10.3 9.5 8.8 8.4 7.3 3.8 9.9 4.0 9.8 7.2 8.9 6.3 0.0 5.3 9.7 16.4 7.1 6.0 2.4 35.7 6.4 7.9 5.6 7.4 CASQ1 "CASQ, PDIB1" ENSG00000143318 "Calsequestrin 1" P31415 1 160190575-160201886 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 64 "skeletal muscle: 4442.6;tongue: 1892.7" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 17.6;Rod photoreceptor cells: 25.2;Skeletal myocytes: 20.6" "Cancer enhanced" "Detected in many" "glioma: 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "BEWO: 19.3;HDLM-2: 38.5;RT4: 67.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA007845, CAB015170, HPA026823" Enhanced Approved Nucleoplasm,Mitochondria "Intracellular and membrane" NA NA 270000 "Cluster 33: Striated muscle - Muscle contraction" "Cluster 15: RT4 - Unknown function" "Cluster 37: Myocytes - Muscle contraction" "Nucleoplasm, Mitochondria" "CAB015170: AB_2071451, HPA007845: AB_1078388, HPA026823: AB_10603557" "unprognostic (1.87e-2)" "unprognostic (3.97e-3)" "unprognostic (1.01e-1)" "unprognostic (1.13e-2)" "unprognostic (2.03e-2)" "unprognostic (6.85e-2)" "unprognostic (1.96e-2)" "unprognostic (4.65e-3)" "unprognostic (3.85e-2)" "unprognostic (1.01e-2)" "unprognostic (2.87e-2)" "unprognostic (3.01e-2)" "unprognostic (3.21e-3)" "unprognostic (9.04e-4)" "unprognostic (1.80e-1)" "unprognostic (1.58e-1)" "prognostic favorable (8.93e-5)" 0.9 0.4 5.1 0.8 6.0 1.5 1.4 4.9 10.0 0.5 3.3 3.3 0.5 1.7 0.3 43.1 1.9 1.2 44.9 6.5 3.1 0.3 0.4 0.7 3.0 3.7 3.9 0.4 0.3 0.2 1.0 6.2 3.2 16.2 0.5 49.7 16.7 5.0 4442.6 1.0 1.9 7.4 3.1 1.3 0.8 5.7 3.6 0.5 0.6 1892.7 1.0 5.7 0.9 6.2 0.0 0.0 0.5 0.0 0.2 0.0 19.3 0.0 0.2 0.0 0.0 0.6 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 38.5 0.4 0.1 0.0 0.0 0.1 0.6 4.7 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.7 0.4 0.1 0.0 0.2 0.3 0.2 0.0 67.4 0.0 0.1 0.3 0.2 0.0 3.5 0.1 0.0 0.0 0.2 0.3 0.1 0.0 0.7 0.8 0.3 0.3 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 5.1 6.0 4.9 10.0 6.5 3.1 3.7 3.9 3.2 3.1 3.6 6.2 0.1 0.0 0.0 1.3 0.0 0.1 0.2 0.0 0.0 1.9 0.7 0.9 17.6 0.0 0.0 0.0 2.1 3.0 0.1 0.0 0.0 0.1 3.0 0.1 0.1 0.2 0.0 0.0 2.0 0.0 4.9 0.3 0.0 0.1 3.8 0.0 0.0 0.0 0.4 0.0 0.7 0.0 0.0 0.0 0.3 0.6 0.6 0.2 0.0 0.0 0.0 3.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.7 25.2 0.0 20.6 0.6 1.2 1.9 0.0 0.0 4.5 0.1 0.1 0.0 0.3 CBX6 ENSG00000183741 "Chromobox 6" O95503 22 38861422-38872249 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 88.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048653 Uncertain Approved Nucleoplasm,Mitochondria NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 10: Brain - Neuronal signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Mitochondria" "HPA048653: AB_2680479" "unprognostic (1.65e-2)" "unprognostic (8.66e-2)" "unprognostic (6.20e-3)" "unprognostic (3.14e-3)" "unprognostic (1.56e-1)" "unprognostic (2.62e-1)" "prognostic unfavorable (8.30e-4)" "unprognostic (2.90e-2)" "unprognostic (3.72e-3)" "unprognostic (5.97e-2)" "prognostic favorable (2.46e-6)" "unprognostic (2.75e-1)" "unprognostic (1.27e-3)" "unprognostic (7.39e-2)" "unprognostic (1.03e-1)" "unprognostic (1.94e-1)" "unprognostic (2.26e-2)" 16.3 22.4 67.1 16.5 53.6 28.3 12.3 9.9 83.6 21.0 0.0 39.3 6.5 34.0 14.5 13.3 27.0 11.3 17.7 88.2 10.1 18.7 6.3 17.2 14.2 16.6 14.0 24.4 17.1 49.5 27.5 4.3 10.0 22.0 7.2 8.5 13.7 25.9 8.9 8.2 17.1 26.1 5.5 15.9 20.5 4.3 21.8 12.5 19.0 6.7 15.3 31.0 11.9 30.8 40.3 41.7 9.1 31.3 68.5 38.2 2.8 42.8 24.5 21.8 20.3 21.1 36.5 65.3 31.2 29.5 15.3 46.8 17.0 18.3 11.9 63.1 53.0 6.7 18.5 7.4 37.2 32.6 31.1 57.0 9.1 49.7 23.5 30.1 24.9 18.4 14.9 32.2 15.1 45.5 20.2 9.5 8.1 23.1 31.9 29.9 30.5 25.9 31.3 37.4 44.3 9.8 27.5 36.4 23.7 3.2 25.0 19.3 32.7 18.9 57.9 33.2 29.6 32.9 34.1 23.5 37.0 33.6 40.1 2.2 9.1 4.7 18.6 12.4 15.3 6.7 12.6 13.1 9.1 7.7 10.3 12.6 4.0 9.1 12.5 46.1 8.0 20.0 67.1 53.6 9.9 83.6 88.2 10.1 16.6 14.0 10.0 5.5 21.8 30.8 30.5 16.0 14.7 9.8 25.1 33.9 47.4 18.4 16.5 100.4 42.6 31.6 27.5 52.9 22.1 73.5 39.6 12.4 83.0 9.6 35.2 102.6 1.1 6.9 46.0 36.4 122.7 17.7 28.9 50.1 2.0 48.5 3.1 17.5 6.3 18.7 46.8 32.4 19.8 124.5 27.3 3.2 30.5 40.8 121.1 2.9 74.3 33.2 81.8 14.0 91.1 91.2 57.7 15.1 23.3 46.9 9.1 80.9 24.5 58.9 0.1 51.7 18.0 59.4 72.3 54.4 85.1 4.2 6.8 10.4 34.0 4.7 35.8 40.9 0.9 82.6 CCDC102B "ACY1L, AN, C18orf14, FLJ23594, HsT1731" ENSG00000150636 "Coiled-coil domain containing 102B" Q68D86 18 68715209-69055189 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 28.4" "Cell type enhanced" "Detected in many" "Astrocytes: 72.8;Early spermatids: 138.2;Excitatory neurons: 80.8;Late spermatids: 83.3;Oligodendrocytes: 90.1;Sertoli cells: 78.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 9.1" "Lineage enriched" "Detected in many" 5 "dendritic cells: 9.1" "Cell line enhanced" "Detected in many" "ASC TERT1: 14.2;BJ hTERT+: 29.0;fHDF/TERT166: 26.2;HSkMC: 15.4;Karpas-707: 10.2" "HPA040623, HPA048194" Approved Approved Mitochondria,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria Cytosol "HPA040623: AB_10805715, HPA048194: AB_2680309" "unprognostic (3.92e-2)" "unprognostic (1.62e-1)" "unprognostic (5.58e-2)" "unprognostic (9.50e-3)" "unprognostic (7.13e-2)" "unprognostic (3.50e-1)" "unprognostic (7.87e-3)" "unprognostic (1.36e-1)" "unprognostic (5.59e-2)" "unprognostic (8.62e-3)" "unprognostic (1.95e-1)" "unprognostic (6.04e-2)" "prognostic unfavorable (2.90e-6)" "unprognostic (2.21e-2)" "unprognostic (2.12e-2)" "unprognostic (8.00e-3)" "unprognostic (3.13e-3)" 7.1 2.9 1.5 3.7 1.8 0.7 2.7 0.6 3.5 2.8 0.0 3.8 1.5 1.7 1.1 3.4 1.8 13.6 3.2 1.3 2.0 4.3 1.7 14.3 8.6 2.6 1.6 0.9 1.5 2.6 0.9 28.4 3.1 1.2 4.5 2.2 1.3 1.3 0.6 1.0 2.6 3.7 2.0 2.2 3.6 2.0 2.3 1.5 5.2 1.1 2.0 10.6 1.5 3.6 0.0 0.0 4.0 0.3 3.6 14.2 0.2 0.8 29.0 0.3 0.5 0.1 0.4 0.1 0.6 26.2 0.5 0.4 0.1 0.2 0.4 1.2 0.4 0.8 0.0 1.3 7.0 0.1 0.4 15.4 0.6 0.4 3.5 0.6 0.2 2.0 0.0 10.2 2.4 0.0 0.6 0.3 0.8 0.2 0.5 1.3 0.2 0.5 0.1 0.0 1.7 1.5 0.1 0.0 0.1 1.6 0.3 1.3 4.0 0.6 0.2 0.2 0.3 4.4 0.3 0.8 2.1 1.7 2.5 0.0 0.1 0.3 1.0 0.2 0.9 0.5 0.6 0.8 0.2 0.6 1.8 1.1 0.0 1.0 0.2 9.1 0.3 0.3 1.5 1.8 0.6 3.5 1.3 2.0 2.6 1.6 3.1 2.0 2.3 3.6 11.5 0.0 2.2 72.8 4.4 0.6 0.8 0.8 0.6 6.4 2.7 2.9 10.0 0.0 2.1 3.7 6.2 0.8 12.4 0.4 5.9 0.7 138.2 2.9 6.7 6.8 0.0 3.0 80.8 1.8 0.6 15.3 0.0 1.1 2.5 5.7 8.6 0.8 3.2 6.7 33.6 0.2 0.0 1.9 1.8 83.3 32.3 3.3 0.0 44.0 2.1 11.9 7.2 36.2 90.1 0.2 2.6 9.1 2.2 0.4 0.3 5.3 1.5 13.4 78.9 3.8 37.3 1.9 5.7 0.7 0.6 0.3 3.8 3.7 0.4 0.6 CCDC184 "C12orf68, LOC387856" ENSG00000177875 "Coiled-coil domain containing 184" Q52MB2 12 48183644-48185926 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.7" "Cell type enhanced" "Detected in many" "Early spermatids: 62.5;Late spermatids: 15.1;Sertoli cells: 46.0" "Cancer enhanced" "Detected in many" "glioma: 6.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 2.7;AF22: 6.3;hTERT-RPE1: 2.4;SH-SY5Y: 4.3;U-2 OS: 2.5;U-87 MG: 3.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039947, HPA041715" Uncertain Approved Mitochondria,Cytosol No No "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 12: NES - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "Mitochondria, Cytosol" "HPA039947: AB_2676764, HPA041715: AB_2677634" "unprognostic (2.02e-1)" "unprognostic (1.16e-2)" "unprognostic (6.97e-2)" "unprognostic (2.03e-1)" "unprognostic (1.61e-2)" "unprognostic (4.59e-1)" "unprognostic (1.33e-2)" "unprognostic (6.65e-2)" "unprognostic (9.79e-2)" "unprognostic (8.38e-2)" "unprognostic (1.03e-2)" "unprognostic (1.07e-1)" "unprognostic (5.87e-4)" "unprognostic (1.08e-2)" "unprognostic (2.39e-2)" "unprognostic (2.55e-1)" "unprognostic (2.36e-2)" 1.1 5.3 12.3 0.9 12.0 0.1 1.0 11.2 21.4 3.5 1.1 1.8 0.2 5.4 0.3 0.9 1.0 1.3 2.3 10.8 25.7 0.7 0.3 0.8 0.2 18.3 12.5 7.5 0.6 5.8 11.6 2.3 24.5 1.4 0.4 5.0 0.4 0.8 0.9 0.4 0.9 1.4 7.5 0.9 1.0 6.2 11.9 0.0 0.9 0.4 0.0 2.0 1.5 10.8 0.0 2.7 6.3 0.2 0.5 0.5 0.0 0.2 1.2 0.3 0.5 0.3 0.1 0.0 0.1 0.2 1.6 0.1 0.6 0.1 0.0 1.5 0.1 0.0 0.0 0.0 0.2 0.0 0.5 0.2 0.0 0.0 0.0 2.4 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 4.3 0.5 0.0 0.1 0.1 0.0 0.0 0.1 0.7 2.5 0.0 0.1 0.0 0.0 0.0 3.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.3 12.0 11.2 21.4 10.8 25.7 18.3 12.5 24.5 7.5 11.9 10.8 1.2 0.0 0.0 2.6 1.1 0.0 0.1 0.0 6.2 2.3 0.3 1.9 0.6 0.0 0.6 0.0 0.0 0.7 2.0 0.1 0.0 0.3 62.5 0.4 9.4 3.1 5.3 0.0 5.6 0.0 0.6 11.2 1.1 0.2 0.0 4.2 6.8 0.0 0.9 5.0 12.7 0.0 0.0 0.3 0.0 15.1 0.3 0.5 0.0 1.0 0.0 3.0 0.0 1.5 1.1 0.1 0.0 2.2 0.2 0.1 0.0 0.0 5.1 7.0 46.0 8.6 7.6 12.7 1.8 2.2 0.0 1.5 3.2 1.8 0.0 0.0 CCDC191 KIAA1407 ENSG00000163617 "Coiled-coil domain containing 191" Q8NCU4 3 113964137-114056594 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 37.5;Endometrial ciliated cells: 68.0;Respiratory ciliated cells: 104.2;Rod photoreceptor cells: 40.4;Spermatocytes: 68.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047833 Approved Approved Mitochondria NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" Mitochondria "HPA047833: AB_10961639" "unprognostic (2.59e-2)" "unprognostic (3.93e-2)" "unprognostic (1.86e-1)" "unprognostic (1.31e-2)" "unprognostic (2.60e-1)" "unprognostic (1.42e-2)" "unprognostic (6.57e-2)" "unprognostic (5.91e-2)" "unprognostic (1.08e-1)" "unprognostic (2.90e-1)" "unprognostic (6.33e-2)" "unprognostic (3.64e-2)" "unprognostic (2.53e-2)" "unprognostic (1.51e-1)" "unprognostic (3.62e-1)" "unprognostic (1.54e-1)" "prognostic favorable (3.45e-4)" 2.9 3.3 4.2 3.1 3.9 2.9 4.7 3.1 4.4 4.6 11.7 3.4 1.8 5.3 7.9 2.5 12.1 3.5 1.8 3.8 4.0 7.7 1.9 4.7 4.4 5.7 5.7 4.8 5.1 7.9 10.9 2.1 4.2 5.0 3.2 14.0 3.6 4.8 0.9 7.6 4.0 2.7 4.7 5.6 3.1 9.7 4.0 2.8 8.3 0.8 4.1 3.5 3.3 4.0 3.7 1.9 3.0 2.5 0.8 4.3 0.9 0.8 1.5 1.1 1.8 0.4 4.1 1.0 1.4 1.5 1.0 4.6 0.9 1.6 2.6 0.7 0.7 0.8 0.7 0.3 1.2 1.1 0.5 1.8 4.2 1.5 2.2 2.0 2.2 2.8 0.3 2.1 0.7 1.6 2.3 0.4 0.5 2.4 1.4 1.4 0.6 2.0 4.2 1.8 1.8 2.9 1.5 0.3 1.5 1.5 7.2 0.4 2.4 2.1 0.5 0.9 0.5 3.0 2.6 3.5 2.7 0.6 1.0 0.1 0.8 1.6 0.9 0.8 1.0 8.9 1.8 1.5 0.9 8.3 0.9 1.5 4.4 0.8 0.5 3.7 1.4 0.9 4.2 3.9 3.1 4.4 3.8 4.0 5.7 5.7 4.2 4.7 4.0 4.0 5.2 12.8 14.4 0.0 20.0 0.0 4.0 0.0 4.6 8.9 5.7 7.0 0.0 0.0 16.1 12.9 37.5 1.8 7.9 1.5 13.7 5.4 27.1 68.0 9.5 3.7 4.9 2.1 0.0 3.6 0.5 4.0 9.7 10.6 1.3 9.1 4.6 1.3 3.0 20.2 0.0 2.3 0.0 3.2 0.0 13.1 4.1 3.0 0.0 0.0 2.0 21.6 4.1 0.0 0.0 2.6 1.0 5.3 3.0 1.7 2.4 5.0 104.2 40.4 0.0 6.3 3.5 68.3 13.3 4.3 0.0 0.3 4.5 8.1 2.7 2.8 CCDC58 FLJ33273 ENSG00000160124 "Coiled-coil domain containing 58" Q4VC31 3 122359591-122383231 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 114.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051965 Approved Approved Nucleoli,Mitochondria No No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria Nucleoli "HPA051965: AB_2681676" "unprognostic (1.51e-1)" "unprognostic (1.23e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (1.53e-4)" "unprognostic (5.64e-2)" "unprognostic (6.98e-3)" "prognostic unfavorable (2.94e-5)" "unprognostic (2.72e-2)" "unprognostic (1.03e-2)" "unprognostic (4.98e-3)" "unprognostic (5.26e-3)" "unprognostic (1.84e-2)" "unprognostic (7.11e-3)" "unprognostic (1.03e-3)" "unprognostic (2.58e-1)" "unprognostic (1.86e-1)" "prognostic favorable (7.29e-4)" 14.7 21.0 16.9 15.7 17.8 18.0 19.0 18.2 28.2 10.7 18.4 28.5 22.5 11.7 24.6 23.2 10.6 13.4 27.3 17.1 17.6 46.8 49.8 9.0 23.3 17.8 18.1 13.1 13.8 14.9 7.8 14.4 18.2 11.1 29.1 17.1 11.3 10.6 78.8 15.0 18.6 11.4 17.4 12.1 16.4 9.4 18.1 16.2 18.3 47.2 21.5 22.6 12.5 18.3 135.1 41.9 78.2 50.2 28.5 39.8 100.6 50.5 54.3 119.4 116.4 118.4 66.4 98.0 84.6 38.6 92.7 91.9 127.9 86.3 142.5 34.1 45.3 115.9 28.5 145.6 47.5 174.5 39.5 33.0 43.9 73.5 79.8 50.7 55.9 85.8 133.6 41.6 63.7 67.2 111.7 123.6 150.0 147.2 78.1 72.8 92.9 120.1 83.7 70.3 78.8 38.4 58.5 61.5 150.5 65.3 61.2 112.8 32.6 66.4 86.1 28.6 102.3 32.9 47.5 217.4 75.7 83.3 60.0 0.9 7.7 2.7 15.2 16.7 18.0 20.9 19.9 20.1 16.5 19.2 23.0 22.2 1.4 19.2 14.2 29.2 17.2 6.7 16.9 17.8 18.2 28.2 17.1 17.6 17.8 18.1 18.2 17.4 18.1 18.3 5.7 3.2 17.0 8.1 18.1 15.3 19.1 21.4 21.1 10.5 14.1 10.4 32.0 20.0 22.2 12.9 10.4 21.8 8.4 19.6 54.8 31.4 0.5 24.7 20.5 13.7 5.4 14.1 11.3 30.0 44.7 12.8 16.8 26.2 21.5 14.4 10.8 50.5 17.8 0.0 13.2 27.7 16.2 8.7 7.6 1.5 12.8 8.9 8.8 2.8 19.8 9.7 16.5 11.6 11.8 31.9 14.7 8.2 12.5 30.7 23.9 114.0 22.5 9.6 13.1 15.1 41.8 23.1 31.0 30.8 18.5 15.2 10.9 11.8 35.1 23.0 CD72 "CD72b, LYB2" ENSG00000137101 "CD72 molecule" P21854 9 35609979-35646810 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "lymphoid tissue: 65.0" "Cell type enhanced" "Detected in many" "B-cells: 95.6;dendritic cells: 18.3;Hofbauer cells: 18.7;Kupffer cells: 25.6;Macrophages: 21.1;NK-cells: 19.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "memory B-cell: 232.9;naive B-cell: 413.5" "Lineage enriched" "Detected in all" 20 "B-cells: 413.5" "Cell line enhanced" "Detected in some" "Daudi: 21.4;Karpas-707: 14.5;REH: 7.8;U-698: 44.4" "Region enriched" "Detected in single" 7 "basal ganglia: 4.1" "Low region specificity" "Detected in single" "CAB002505, HPA044658" Enhanced Approved Nucleoplasm,Mitochondria NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Mitochondria" "CAB002505: AB_563629, HPA044658: AB_2679039" "unprognostic (1.13e-2)" "unprognostic (1.26e-2)" "unprognostic (1.21e-2)" "unprognostic (8.82e-2)" "unprognostic (1.87e-2)" "unprognostic (7.81e-2)" "unprognostic (7.11e-2)" "unprognostic (2.95e-1)" "unprognostic (3.29e-2)" "unprognostic (2.02e-2)" "unprognostic (1.95e-1)" "unprognostic (2.89e-1)" "prognostic unfavorable (2.49e-8)" "unprognostic (1.42e-1)" "unprognostic (2.32e-2)" "unprognostic (1.23e-1)" "unprognostic (3.59e-2)" 4.5 2.3 1.9 20.6 2.0 6.7 1.7 2.0 3.3 1.4 4.2 1.9 1.3 1.0 4.8 0.6 1.2 4.1 0.7 1.8 1.8 2.2 6.0 2.8 65.0 2.8 1.8 0.8 2.2 1.1 2.5 3.3 2.4 1.5 1.3 0.4 1.6 0.7 0.6 2.0 8.4 1.6 1.9 53.6 2.6 0.8 3.3 6.9 2.4 0.0 50.2 4.2 0.9 2.3 0.1 0.0 0.6 0.5 0.9 5.2 0.1 0.3 0.1 0.4 0.7 0.0 0.2 21.4 0.1 0.3 0.1 0.0 0.0 0.1 0.5 1.8 0.4 0.6 0.2 0.0 0.5 0.3 4.1 1.5 0.0 0.2 0.4 0.9 0.0 4.9 0.0 14.5 1.1 0.0 0.3 2.7 0.2 0.0 0.1 7.8 0.0 5.5 0.0 0.0 0.3 0.5 0.0 0.1 0.1 0.3 0.2 0.2 0.1 0.7 0.2 0.2 0.0 0.3 0.3 44.4 0.8 0.5 0.0 0.6 2.0 0.3 3.1 3.5 4.3 232.9 1.5 2.2 20.2 413.5 0.7 2.4 1.4 10.6 0.5 11.0 1.7 14.8 1.9 2.0 2.0 3.3 1.8 1.8 2.8 1.8 2.4 1.9 3.3 2.3 0.7 0.0 0.6 5.9 95.6 1.0 0.5 0.9 0.6 0.0 1.3 1.3 1.1 1.5 0.4 3.7 0.0 0.2 18.3 0.7 0.0 0.8 0.2 0.4 0.6 0.9 1.8 2.7 1.0 0.7 0.3 0.9 1.1 0.4 0.0 0.8 0.7 0.2 18.7 0.0 1.2 0.2 0.0 25.6 14.6 0.3 0.9 21.1 0.0 0.0 3.0 0.6 19.6 2.0 4.4 1.1 0.0 0.4 2.7 0.5 0.6 0.7 1.3 0.7 0.0 0.5 0.9 1.1 1.7 0.2 1.1 0.3 5.9 0.5 0.4 0.4 CDK5RAP1 "C20orf34, C42, CGI-05, HSPC167" ENSG00000101391 "CDK5 regulatory subunit associated protein 1" Q96SZ6 20 33358839-33401561 "Enzymes, Predicted intracellular proteins" "tRNA processing" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ionocytes: 128.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CACO-2: 116.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066301 Approved "Nuclear speckles,Mitochondria" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 39: CACO-2 - Unknown function" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles" Mitochondria "HPA066301: AB_2685653" "unprognostic (2.86e-1)" "unprognostic (7.19e-2)" "unprognostic (1.31e-1)" "unprognostic (1.66e-3)" "unprognostic (2.25e-1)" "unprognostic (6.49e-2)" "unprognostic (7.68e-3)" "unprognostic (2.18e-2)" "unprognostic (5.10e-1)" "unprognostic (2.36e-1)" "unprognostic (5.90e-3)" "prognostic unfavorable (8.07e-4)" "unprognostic (3.51e-2)" "unprognostic (8.13e-2)" "unprognostic (1.28e-1)" "unprognostic (4.87e-1)" "unprognostic (1.06e-1)" 9.1 8.4 4.9 10.7 5.7 18.6 10.5 4.9 5.3 8.4 6.3 9.0 8.9 9.8 11.5 9.3 9.2 6.2 12.0 5.7 4.3 9.0 11.1 9.0 12.7 4.5 4.4 8.6 7.6 11.2 7.2 10.3 4.1 8.4 12.2 15.9 10.6 8.7 20.9 12.6 9.5 10.8 3.9 10.3 9.7 9.3 4.6 11.3 11.9 22.8 15.2 8.7 7.9 4.9 27.0 27.6 18.6 17.1 17.4 13.4 40.7 15.8 22.5 45.0 46.9 116.5 23.9 47.3 21.0 17.2 29.0 39.1 31.8 45.1 34.8 8.9 17.3 57.1 30.8 45.1 20.3 36.6 17.4 17.5 18.9 30.2 35.9 11.4 24.9 13.6 36.7 19.3 20.0 26.6 37.8 27.5 14.1 30.2 40.1 27.8 42.4 36.1 24.5 23.6 25.2 14.3 50.5 24.4 33.0 20.9 34.7 17.4 18.4 33.3 27.3 23.1 27.4 16.6 20.1 34.8 19.8 39.3 15.9 4.5 17.3 11.8 18.5 22.3 22.2 21.4 18.3 18.0 19.1 14.1 16.2 14.0 0.9 21.6 18.4 13.4 17.3 15.1 4.9 5.7 4.9 5.3 5.7 4.3 4.5 4.4 4.1 3.9 4.6 4.9 13.2 16.0 20.0 26.8 18.6 12.1 10.3 21.1 10.8 25.6 9.3 8.9 15.7 11.5 18.6 7.3 27.1 31.4 18.2 7.4 13.7 17.6 2.9 10.1 10.3 11.4 12.6 12.2 36.7 18.3 18.5 10.4 13.3 14.6 29.8 15.6 6.1 15.6 17.5 11.8 25.4 8.6 128.1 10.1 12.6 2.8 13.1 13.5 10.6 10.3 15.2 16.5 19.6 16.1 26.6 13.0 9.0 10.5 19.3 8.3 13.8 15.3 20.9 39.9 19.7 14.8 15.3 32.6 23.6 8.5 10.4 16.0 22.3 16.1 12.6 8.9 CDRT4 FLJ36674 ENSG00000239704 "CMT1A duplicated region transcript 4" Q8N9R6 17 15436015-15503608 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 36 "Early spermatids: 65.8;Late spermatids: 202.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 10.1;NB-4: 8.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA021590 Uncertain Approved Mitochondria NA NA "Cluster 46: Basophils - DNA binding" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "HPA021590: AB_1848906" "unprognostic (5.46e-6)" "unprognostic (9.47e-2)" "unprognostic (7.53e-2)" "unprognostic (1.31e-1)" "unprognostic (3.51e-2)" "unprognostic (7.74e-3)" "unprognostic (9.29e-2)" "unprognostic (2.12e-2)" "unprognostic (3.93e-2)" "unprognostic (1.39e-1)" "unprognostic (2.10e-5)" "unprognostic (2.00e-3)" "unprognostic (1.74e-6)" "unprognostic (1.00e-1)" "unprognostic (4.17e-1)" "unprognostic (4.18e-1)" "unprognostic (9.27e-2)" 5.8 18.7 14.1 1.7 12.9 6.1 9.3 14.3 12.0 19.3 13.2 10.6 0.9 8.8 23.7 10.8 20.7 3.2 5.7 12.2 13.9 16.5 10.0 8.8 5.0 11.7 13.5 20.4 19.8 1.5 48.0 2.5 11.6 20.1 4.6 11.8 15.9 3.8 1.8 21.8 11.9 2.3 8.4 15.9 11.4 15.3 14.7 3.2 23.5 0.8 2.9 9.0 12.8 12.0 2.5 2.2 2.8 1.0 2.4 1.7 2.9 0.9 2.5 1.1 1.0 1.4 0.7 0.0 1.2 1.4 0.2 0.8 3.0 2.4 1.7 0.5 0.4 0.4 2.0 10.1 0.7 0.9 3.9 1.9 3.6 1.6 4.0 4.3 2.6 1.0 0.5 1.6 2.1 0.4 1.0 8.0 0.9 0.4 0.8 0.4 0.0 0.0 2.9 2.0 0.4 1.3 0.8 0.4 0.8 6.2 1.1 2.0 2.4 0.3 1.1 1.0 1.0 2.2 0.9 0.1 0.0 0.0 0.3 0.9 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.1 14.1 12.9 14.3 12.0 12.2 13.9 11.7 13.5 11.6 8.4 14.7 12.0 0.4 0.0 1.1 0.0 0.3 0.1 0.2 0.2 0.0 1.4 0.6 0.5 0.1 0.0 0.1 0.0 0.0 0.4 0.2 0.6 0.0 0.8 65.8 0.7 0.2 0.2 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.4 2.5 1.4 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 202.7 0.0 0.1 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.6 1.8 0.0 0.0 0.4 0.4 0.0 3.7 1.5 0.0 0.3 0.2 1.0 0.7 0.0 0.0 0.1 0.2 0.5 1.0 0.3 CEACAM19 CEAL1 ENSG00000186567 "CEA cell adhesion molecule 19" Q7Z692 19 44662278-44684359 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 7.9;Skeletal myocytes: 8.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 12.2;RPTEC TERT1: 15.8;TIME: 20.9" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hippocampal formation: 1.1" "HPA014462, HPA052865" Uncertain Approved Nucleoplasm,Nucleoli,Mitochondria NA NA "Cluster 50: Non-specific - Ribosome" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "Nucleoli, Mitochondria" Nucleoplasm "HPA014462: AB_2669006, HPA052865: AB_2681976" "unprognostic (2.91e-1)" "unprognostic (5.29e-3)" "unprognostic (6.96e-3)" "unprognostic (1.45e-2)" "unprognostic (3.73e-2)" "unprognostic (8.43e-2)" "unprognostic (5.22e-2)" "unprognostic (1.15e-2)" "unprognostic (9.98e-2)" "unprognostic (1.14e-1)" "unprognostic (1.78e-3)" "unprognostic (1.77e-1)" "unprognostic (3.26e-9)" "unprognostic (8.01e-3)" "unprognostic (9.62e-2)" "unprognostic (1.31e-1)" "unprognostic (2.70e-1)" 3.9 5.6 3.7 1.3 3.7 1.5 3.8 4.9 5.1 7.0 3.5 4.7 3.0 5.2 1.7 5.1 6.8 2.4 11.7 4.0 3.8 9.4 8.2 8.2 1.1 2.8 3.0 6.6 8.9 1.5 7.0 2.2 2.7 7.8 3.4 2.4 5.7 3.1 13.8 12.4 3.8 3.1 1.9 3.5 4.6 5.7 3.7 0.9 6.5 3.4 2.2 4.2 8.7 4.7 5.1 10.3 1.5 1.0 3.5 4.0 3.8 2.8 4.2 0.9 1.8 0.4 1.1 0.1 1.0 3.8 1.0 6.2 2.6 1.1 0.8 1.5 5.8 0.1 6.7 1.7 3.6 0.2 1.0 1.3 10.0 2.6 6.1 12.2 2.4 0.7 0.3 0.3 1.4 1.2 0.0 0.6 0.9 1.4 1.1 0.0 1.8 0.2 15.8 1.2 1.9 0.5 1.1 1.1 0.9 1.4 1.4 0.3 20.9 0.4 6.8 1.5 0.9 0.1 0.3 0.0 0.5 2.0 1.7 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 3.7 3.7 4.9 5.1 4.0 3.8 2.8 3.0 2.7 1.9 3.7 4.7 3.6 3.2 2.2 2.0 0.0 2.0 0.9 2.1 1.2 2.9 1.9 1.5 4.5 1.5 2.4 0.0 0.0 0.2 0.1 2.1 0.0 1.6 3.8 0.9 0.9 4.1 1.8 0.0 7.9 3.3 0.2 1.0 3.6 2.4 0.0 0.8 4.6 2.6 0.3 0.0 6.1 2.3 4.1 0.6 0.8 1.9 3.1 0.5 0.0 1.9 0.4 0.3 1.0 2.0 2.4 4.5 2.6 2.6 0.0 1.8 1.2 0.4 1.8 0.6 0.0 8.8 1.7 3.1 0.9 1.2 6.0 0.0 0.2 1.6 2.5 0.9 CEND1 "BM88, FLJ90066" ENSG00000184524 "Cell cycle exit and neuronal differentiation 1" Q8N111 11 787115-790113 "Predicted membrane proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 234.7" "Cell type enhanced" "Detected in some" "Bipolar cells: 94.2;Excitatory neurons: 42.9;Horizontal cells: 75.7;Inhibitory neurons: 45.6;Rod photoreceptor cells: 25.5" "Cancer enriched" "Detected in many" 13 "glioma: 24.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 13.6;Karpas-707: 31.0;SCLC-21H: 54.1;SH-SY5Y: 20.4;U-266/70: 21.1;U-87 MG: 28.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042527 Enhanced Supported Approved Mitochondria NA NA "Cluster 35: T-regs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" Mitochondria "HPA042527: AB_2678038" "unprognostic (4.62e-3)" "unprognostic (1.34e-4)" "unprognostic (9.66e-3)" "unprognostic (1.27e-2)" "prognostic unfavorable (4.38e-5)" "unprognostic (2.20e-3)" "unprognostic (4.11e-2)" "unprognostic (6.72e-2)" "unprognostic (2.60e-2)" "unprognostic (2.26e-1)" "unprognostic (2.00e-3)" "unprognostic (4.24e-3)" "unprognostic (1.94e-3)" "unprognostic (4.43e-2)" "unprognostic (1.71e-1)" "unprognostic (1.40e-1)" "unprognostic (1.03e-1)" 0.1 5.5 55.0 1.0 78.8 0.0 0.1 56.9 234.7 0.2 20.0 4.0 0.6 0.9 0.2 0.4 0.1 0.0 1.1 67.4 79.3 1.2 0.3 0.2 0.3 103.8 57.9 0.2 0.2 0.3 26.0 0.0 93.4 3.2 0.1 7.6 0.2 1.5 0.2 0.2 1.4 0.5 21.6 0.3 0.9 0.3 106.3 0.0 0.2 0.0 0.1 0.8 1.1 116.6 0.0 0.7 0.7 1.4 0.2 0.3 0.2 1.3 0.4 0.4 0.6 0.0 0.0 0.0 0.0 0.5 13.6 0.5 0.0 0.0 0.0 8.5 0.3 0.0 0.1 0.0 0.1 0.0 5.3 0.6 0.0 0.8 0.0 0.0 0.2 0.0 0.0 31.0 0.5 0.1 0.3 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.0 0.0 54.1 20.4 0.0 0.4 0.0 0.0 0.0 0.1 0.2 0.1 0.0 1.2 0.9 21.1 6.2 1.3 28.6 0.2 0.4 0.0 0.0 0.0 0.2 0.2 0.0 0.8 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 55.0 78.8 56.9 234.7 67.4 79.3 103.8 57.9 93.4 21.6 106.3 116.6 0.1 0.0 0.0 17.6 0.5 0.1 0.1 0.0 0.0 94.2 0.0 0.0 0.5 0.0 0.0 0.0 10.4 0.0 0.3 0.0 0.0 0.1 0.2 0.0 0.4 0.6 0.0 0.0 42.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.1 75.7 45.6 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 6.5 0.0 6.7 0.0 15.1 10.0 0.0 0.0 0.0 1.0 0.1 0.0 0.1 0.0 25.5 0.0 0.1 1.7 0.0 0.7 0.0 0.0 0.0 0.3 0.2 0.1 0.0 CFAP52 "FLJ37528, WDR16, WDRPUH" ENSG00000166596 "Cilia and flagella associated protein 52" Q8N1V2 17 9576627-9643447 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 13.7;choroid plexus: 18.2;fallopian tube: 57.8" "Group enriched" "Detected in some" 6 "Early spermatids: 32.4;Endometrial ciliated cells: 99.6;Respiratory ciliated cells: 81.6;Spermatocytes: 33.9" "Group enriched" "Detected in some" 4 "endometrial cancer: 1.5;glioma: 1.7;lung cancer: 0.6;ovarian cancer: 0.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 1.7;MCF7: 2.1;OE19: 2.7;REH: 1.4;T-47d: 1.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023247, HPA030635" Enhanced Approved Nucleoplasm,Mitochondria NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 21: OE19 - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" Mitochondria Nucleoplasm "HPA023247: AB_1858797, HPA030635: " "unprognostic (1.76e-2)" "unprognostic (2.31e-1)" "unprognostic (1.38e-1)" "unprognostic (1.68e-2)" "unprognostic (2.09e-1)" "unprognostic (2.04e-1)" "unprognostic (3.99e-1)" "unprognostic (3.16e-2)" "unprognostic (2.11e-1)" "unprognostic (3.66e-1)" "unprognostic (2.22e-2)" "unprognostic (2.66e-1)" "unprognostic (7.85e-2)" "unprognostic (1.85e-1)" "unprognostic (9.23e-2)" "unprognostic (4.50e-2)" "unprognostic (7.09e-2)" 0.0 0.3 3.8 0.0 4.3 0.0 0.1 2.3 2.9 2.3 18.2 0.1 0.7 1.1 0.1 0.2 57.8 0.2 0.0 4.0 4.1 0.3 0.2 4.4 0.0 10.7 13.7 0.2 0.2 0.3 3.2 0.2 8.4 0.3 0.0 2.4 1.2 0.2 0.0 0.2 0.7 0.0 9.9 0.0 0.1 12.2 3.9 0.3 0.6 0.3 0.0 0.1 0.1 6.6 0.8 0.8 0.0 0.3 0.5 0.4 0.4 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.2 0.0 0.6 0.9 0.0 0.0 0.0 0.2 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 2.1 0.0 0.3 0.1 2.7 0.0 1.4 0.0 0.0 0.2 0.4 0.3 0.0 0.3 0.5 0.0 0.3 1.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 4.3 2.3 2.9 4.0 4.1 10.7 13.7 8.4 9.9 3.9 6.6 0.2 0.0 2.3 1.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.1 0.3 0.0 9.9 0.0 6.2 0.8 0.0 0.0 1.9 0.1 32.4 99.6 0.9 0.3 0.0 0.0 9.7 0.2 0.2 0.3 0.0 1.7 0.0 0.1 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 0.0 6.4 1.8 0.0 0.0 1.0 0.0 0.7 0.0 7.1 1.1 0.1 0.0 1.9 0.0 0.3 0.0 0.5 81.6 3.1 0.0 0.1 0.2 33.9 0.8 0.0 0.0 1.0 0.1 0.1 0.0 0.1 CHAC1 MGC4504 ENSG00000128965 "ChaC glutathione specific gamma-glutamylcyclotransferase 1" Q9BUX1 15 40952962-40956512 "Enzymes, Predicted intracellular proteins" "Apoptosis, Neurogenesis, Notch signaling pathway, Unfolded protein response" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 68.6;skeletal muscle: 68.4" "Cell type enhanced" "Detected in many" "Distal tubular cells: 35.2;Exocrine glandular cells: 27.8;Gastric mucus-secreting cells: 33.6;Pancreatic endocrine cells: 19.3;Plasma cells: 21.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 109.5;HHSteC: 80.7;hTCEpi: 130.8;SK-MEL-30: 95.0;U-266/70: 81.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA042708, HPA043505" Approved Approved Mitochondria NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 1: Pancreatic cells - Digestion" Mitochondria "HPA042708: AB_2678125, HPA043505: AB_2678518" "unprognostic (6.04e-3)" "unprognostic (2.81e-2)" "unprognostic (7.47e-2)" "unprognostic (2.84e-3)" "unprognostic (6.57e-3)" "unprognostic (2.00e-2)" "unprognostic (5.59e-2)" "unprognostic (2.43e-1)" "unprognostic (2.01e-1)" "unprognostic (1.72e-1)" "unprognostic (3.11e-1)" "unprognostic (1.51e-1)" "prognostic unfavorable (2.23e-7)" "unprognostic (1.37e-2)" "unprognostic (1.44e-1)" "unprognostic (1.67e-2)" "unprognostic (3.91e-2)" 9.1 0.6 12.3 1.4 12.0 1.8 0.9 11.1 30.7 2.1 7.1 1.9 2.0 0.7 1.5 23.3 1.7 1.8 2.4 11.4 16.6 4.0 11.5 2.0 0.9 13.0 14.5 0.7 68.6 1.4 1.9 0.8 16.9 1.3 0.8 1.1 5.1 1.0 68.4 1.6 1.4 0.8 12.6 0.9 14.8 0.7 17.6 0.5 1.5 11.7 3.0 4.3 3.7 16.6 9.1 6.0 1.5 27.2 4.3 3.2 11.1 53.5 109.5 5.8 15.5 15.1 2.2 2.8 4.1 4.8 17.2 6.0 12.0 4.4 4.1 10.4 2.5 2.5 1.6 0.0 80.7 7.3 0.1 36.1 130.8 17.1 23.2 1.8 5.4 62.3 7.7 12.5 4.8 5.5 5.3 0.1 4.9 31.0 21.3 4.8 0.1 12.8 3.0 3.5 5.3 7.9 1.6 9.5 95.0 3.3 3.6 51.1 1.8 1.3 16.1 1.5 9.4 81.1 19.0 11.0 4.8 10.3 12.7 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 12.3 12.0 11.1 30.7 11.4 16.6 13.0 14.5 16.9 12.6 17.6 16.6 6.2 0.0 2.0 0.3 3.1 2.8 3.8 11.5 3.4 2.6 2.2 2.4 4.6 4.3 6.5 0.0 2.1 0.3 2.6 8.0 35.2 6.4 0.1 1.8 0.4 2.7 3.5 3.2 1.3 27.8 0.3 0.6 33.6 2.1 0.0 0.4 1.8 0.7 0.4 0.0 1.5 8.0 6.1 0.3 1.5 0.0 0.3 0.8 5.4 0.0 1.0 0.5 0.0 0.5 0.2 19.3 2.3 0.0 21.4 6.5 0.8 0.3 3.3 0.4 0.0 0.3 3.2 1.1 1.1 1.5 4.3 3.4 1.6 0.5 4.8 14.6 CHCHD5 "C2orf9, MGC11104, MIC14, MIX14" ENSG00000125611 "Coiled-coil-helix-coiled-coil-helix domain containing 5" Q9BSY4 2 112584240-112589275 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038263 Approved Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 22: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA038263: AB_10671525" "unprognostic (3.56e-2)" "unprognostic (3.41e-2)" "unprognostic (3.36e-2)" "unprognostic (4.57e-2)" "unprognostic (1.85e-1)" "unprognostic (7.75e-2)" "unprognostic (2.72e-1)" "unprognostic (7.18e-3)" "unprognostic (8.04e-2)" "unprognostic (4.96e-2)" "unprognostic (2.07e-1)" "unprognostic (4.95e-2)" "unprognostic (1.39e-2)" "unprognostic (3.91e-2)" "unprognostic (2.36e-1)" "unprognostic (1.87e-1)" "unprognostic (1.12e-2)" 19.1 28.9 20.6 12.4 22.0 18.3 22.4 22.6 28.7 18.5 19.8 19.2 18.0 17.8 6.4 28.2 19.6 14.4 24.5 20.0 21.7 35.8 40.2 17.8 14.6 21.4 21.6 15.8 46.1 28.1 31.7 9.8 21.3 22.2 6.3 5.7 16.5 12.6 38.9 23.3 17.2 6.5 21.5 18.5 25.4 22.9 22.6 16.7 27.1 18.7 7.9 19.6 18.8 21.9 32.5 53.1 23.3 0.1 9.3 19.7 22.0 14.0 18.2 28.3 20.0 58.1 39.0 24.7 54.4 19.4 23.9 23.4 8.9 31.2 3.8 26.8 43.2 33.4 15.6 46.4 40.8 28.5 22.5 26.5 26.3 37.4 22.8 13.2 15.8 0.1 35.1 36.5 18.1 80.3 25.8 45.1 26.0 24.1 25.9 0.9 19.3 48.7 37.8 29.1 29.7 33.4 17.7 26.3 31.6 6.2 33.9 24.9 22.0 28.2 39.7 17.2 20.4 65.0 66.3 29.1 39.1 7.7 33.9 22.1 69.0 68.6 49.9 66.6 42.1 49.3 46.8 47.5 64.1 63.2 48.1 49.9 38.3 62.3 62.6 81.3 78.6 61.9 20.6 22.0 22.6 28.7 20.0 21.7 21.4 21.6 21.3 21.5 22.6 21.9 39.3 9.6 13.9 2.0 41.1 43.1 65.1 153.3 51.8 19.2 100.0 109.6 40.4 90.1 73.8 82.8 10.4 131.9 41.2 138.5 219.2 109.7 188.8 138.1 63.5 44.3 91.7 44.6 2.2 176.7 109.5 43.8 67.8 79.6 24.7 50.8 51.4 211.4 123.9 6.7 2.8 107.3 97.6 122.0 63.5 290.9 30.7 63.7 53.4 1.0 101.0 61.5 87.6 1.5 4.4 123.2 140.1 28.2 41.0 76.8 184.7 286.7 99.3 28.3 13.1 33.9 47.8 141.8 39.4 112.2 58.1 92.8 44.6 89.2 97.7 85.7 CIBAR1 "FAM92A, FAM92A1, FLJ38979" ENSG00000188343 "CBY1 interacting BAR domain containing 1" A1XBS5 8 93698561-93731527 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "testis: 110.2" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 13.3;Extravillous trophoblasts: 14.1;Fibroblasts: 8.4;Hofbauer cells: 6.4;Syncytiotrophoblasts: 3.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034760, HPA058942" Enhanced Approved Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 68: Epididymis - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 33: Fibroblasts - ECM organization" Mitochondria "HPA034760: AB_10599947, HPA058942: AB_2732628" "unprognostic (2.65e-3)" "unprognostic (6.81e-2)" "unprognostic (2.48e-3)" "unprognostic (2.44e-1)" "unprognostic (1.62e-2)" "unprognostic (2.93e-1)" "unprognostic (3.56e-1)" "unprognostic (3.13e-1)" "unprognostic (1.20e-1)" "unprognostic (2.14e-1)" "unprognostic (2.28e-3)" "unprognostic (1.97e-1)" "unprognostic (1.71e-1)" "unprognostic (6.85e-3)" "unprognostic (1.97e-1)" "unprognostic (1.48e-1)" "unprognostic (3.07e-2)" 14.3 23.9 17.5 5.6 18.8 3.5 10.9 18.6 25.0 16.5 22.9 14.2 3.2 16.0 26.2 5.0 13.1 14.1 25.3 17.8 16.2 20.2 18.5 9.9 5.7 13.4 14.5 18.0 21.1 21.5 20.8 10.1 13.3 12.1 5.9 14.1 5.7 11.6 10.3 6.6 7.7 15.0 12.9 5.7 9.8 110.2 17.1 5.0 14.5 11.1 3.1 14.6 9.3 17.4 37.8 20.0 52.9 54.6 55.8 78.9 14.0 34.2 49.8 45.2 43.5 3.5 8.6 3.2 42.7 50.7 52.0 26.6 54.0 32.5 41.0 1.2 29.5 21.5 20.8 18.7 64.1 1.0 5.5 50.4 14.3 44.3 36.0 64.9 49.0 18.1 13.4 1.7 35.8 14.2 23.8 4.1 22.2 0.8 1.1 2.3 39.7 0.8 35.3 8.7 15.3 18.7 24.4 0.5 41.6 23.7 8.2 11.8 27.2 44.2 17.4 46.3 28.0 2.6 2.7 1.2 38.8 3.0 15.8 0.1 1.7 0.0 0.1 1.2 0.2 0.4 0.4 0.1 2.9 0.0 0.1 0.3 0.0 1.3 0.1 0.3 0.8 0.5 17.5 18.8 18.6 25.0 17.8 16.2 13.4 14.5 13.3 12.9 17.1 17.4 2.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 14.1 8.4 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 CKS1B "CKS1, ckshs1" ENSG00000173207 "CDC28 protein kinase regulatory subunit 1B" P61024 1 154974653-154979251 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 651.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA003424, HPA030762" Approved Approved Nucleoplasm,Vesicles,Mitochondria,Cytosol NA Yes "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Mitochondria, Cytosol" "Nucleoplasm, Vesicles" "HPA003424: AB_2666948, HPA030762: AB_10670044" "unprognostic (1.06e-2)" "unprognostic (1.62e-1)" "unprognostic (2.84e-1)" "prognostic unfavorable (7.89e-4)" "unprognostic (1.34e-1)" "unprognostic (2.59e-2)" "prognostic unfavorable (2.94e-5)" "unprognostic (2.01e-3)" "prognostic unfavorable (3.12e-5)" "unprognostic (3.63e-2)" "prognostic unfavorable (6.13e-4)" "unprognostic (3.19e-1)" "prognostic unfavorable (6.03e-7)" "unprognostic (3.12e-2)" "unprognostic (1.44e-1)" "prognostic favorable (4.87e-4)" "unprognostic (1.37e-1)" 59.0 31.9 15.0 33.6 15.8 117.7 67.8 16.4 19.8 44.3 15.0 49.4 40.8 35.0 36.8 61.6 40.9 22.2 35.5 15.4 16.2 37.9 73.3 29.0 71.3 17.5 15.8 31.7 22.4 35.5 18.4 50.6 17.7 26.1 50.5 6.0 28.4 32.9 14.5 51.2 44.3 34.8 17.4 37.0 35.5 48.6 15.7 88.7 30.1 23.5 74.1 30.1 42.6 18.8 459.2 616.5 455.9 245.3 66.9 68.1 361.4 209.1 166.8 463.4 367.8 599.9 653.4 433.8 345.9 143.2 251.2 410.6 468.0 305.2 428.7 392.9 293.9 294.6 249.9 426.5 19.4 359.7 257.9 39.8 132.2 391.4 532.8 91.5 232.5 298.2 486.6 566.8 353.9 452.8 337.3 273.9 575.3 442.1 547.6 334.8 373.6 554.3 165.6 164.2 184.3 463.9 313.6 292.0 347.3 530.2 391.6 492.9 126.0 282.5 292.4 237.0 505.3 348.9 734.7 617.0 179.6 300.1 399.8 2.2 13.0 6.9 19.8 82.0 24.4 74.2 28.0 27.1 22.1 70.4 34.0 32.8 1.7 28.7 105.4 92.6 33.3 28.1 15.0 15.8 16.4 19.8 15.4 16.2 17.5 15.8 17.7 17.4 15.7 18.8 31.7 12.8 33.3 1.3 46.5 217.6 101.3 170.6 74.0 3.4 90.6 140.5 9.2 87.2 63.1 29.5 0.0 224.0 40.7 48.3 80.3 93.0 15.8 43.1 24.6 51.9 20.4 140.1 0.8 112.1 651.8 84.6 20.9 28.3 21.0 66.7 29.6 89.8 132.1 1.7 0.8 57.4 120.1 46.0 121.0 21.7 76.1 37.4 113.8 0.0 41.3 20.7 20.6 0.5 3.5 119.0 41.7 45.9 38.4 130.2 63.1 87.5 52.1 3.0 19.7 50.6 53.0 124.7 151.0 74.9 203.6 131.9 40.7 27.2 80.0 99.5 CKS2 ENSG00000123975 "CDC28 protein kinase regulatory subunit 2" P33552 9 89311195-89316703 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 177.3;testis: 186.3" "Cell type enhanced" "Detected in many" "Langerhans cells: 474.6;Spermatocytes: 692.7;Spermatogonia: 503.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 187.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003424, HPA030762" Approved Approved Nucleoplasm,Vesicles,Mitochondria,Cytosol NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "Mitochondria, Cytosol" "Nucleoplasm, Vesicles" "HPA003424: AB_2666948, HPA030762: AB_10670044" "unprognostic (8.30e-2)" "unprognostic (3.00e-1)" "unprognostic (1.50e-2)" "unprognostic (2.80e-2)" "unprognostic (2.96e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (2.51e-6)" "unprognostic (3.57e-3)" "unprognostic (7.04e-2)" "unprognostic (1.34e-2)" "prognostic unfavorable (6.85e-4)" "unprognostic (1.24e-2)" "prognostic unfavorable (1.78e-5)" "unprognostic (2.13e-3)" "unprognostic (1.44e-1)" "unprognostic (2.84e-1)" "unprognostic (1.84e-1)" 13.6 82.9 9.6 38.5 10.0 177.3 20.1 11.9 26.9 10.1 11.8 44.1 43.3 13.0 8.8 53.2 12.1 18.7 10.3 12.7 10.3 35.6 31.2 24.0 102.8 10.5 10.1 9.4 4.2 19.8 4.8 44.3 11.0 15.0 41.0 27.9 10.8 17.8 9.4 19.9 33.1 17.6 10.6 32.6 20.4 186.3 10.8 121.1 12.8 4.8 84.7 26.5 19.9 11.3 685.9 570.1 342.6 230.6 98.7 89.1 249.5 396.1 211.4 428.1 340.0 236.1 328.6 504.9 228.4 149.1 761.4 466.5 415.5 305.1 488.2 398.1 335.5 257.5 378.9 637.5 42.4 531.7 281.2 33.0 69.2 307.2 269.1 162.9 403.2 409.1 313.2 430.6 556.0 509.1 420.7 928.3 501.6 795.5 521.5 358.4 376.4 303.7 342.8 153.5 288.4 171.7 328.7 314.9 324.5 318.4 379.7 304.2 231.4 184.1 350.3 449.6 588.2 345.9 759.2 415.3 271.3 303.1 268.5 40.8 19.5 44.1 22.6 26.5 25.3 61.3 30.4 21.9 22.5 44.7 16.3 21.8 14.5 40.9 14.8 187.9 62.7 23.6 9.6 10.0 11.9 26.9 12.7 10.3 10.5 10.1 11.0 10.6 10.8 11.3 138.6 38.5 103.9 0.3 175.7 280.2 92.1 126.1 259.0 4.1 107.2 169.0 61.3 5.7 49.9 14.7 0.0 231.1 201.1 79.4 23.5 20.1 37.3 149.7 66.4 66.1 122.3 266.9 1.2 11.2 379.4 63.1 74.9 250.2 145.0 144.7 29.3 25.0 184.6 0.0 1.9 164.9 111.9 40.5 474.6 77.0 25.7 164.3 140.5 1.9 31.0 26.1 28.8 1.0 1.1 31.1 67.1 16.6 89.3 72.1 37.6 209.7 32.8 7.3 46.0 75.2 206.5 692.7 503.6 197.5 299.1 199.5 156.0 70.3 162.7 102.1 CMSS1 "C3orf26, MGC4308" ENSG00000184220 "Cms1 ribosomal small subunit homolog" Q9BQ75 3 99817837-100181732 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 215.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042820 Uncertain Approved "Nucleoplasm,Nuclear membrane,Nucleoli,Mitochondria" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoli "Nucleoplasm, Nuclear membrane, Mitochondria" "HPA042820: AB_10795763" "unprognostic (1.50e-1)" "unprognostic (8.28e-2)" "unprognostic (4.61e-2)" "prognostic unfavorable (3.15e-6)" "unprognostic (2.13e-2)" "unprognostic (2.39e-3)" "prognostic unfavorable (5.92e-10)" "unprognostic (1.50e-1)" "unprognostic (5.92e-2)" "unprognostic (5.83e-2)" "unprognostic (6.71e-2)" "prognostic unfavorable (3.10e-4)" "unprognostic (2.18e-3)" "unprognostic (1.56e-1)" "unprognostic (2.26e-1)" "unprognostic (3.25e-1)" "unprognostic (4.04e-2)" 24.5 33.1 23.0 15.8 21.7 20.8 23.4 26.7 30.1 22.4 17.8 21.0 8.6 21.8 9.7 15.8 20.9 10.5 28.2 21.8 20.9 20.7 15.0 15.8 17.1 22.8 20.1 23.6 26.7 21.8 24.5 11.6 19.6 16.0 11.6 24.6 14.0 13.3 69.4 17.4 12.6 13.2 17.9 13.8 16.4 30.3 21.3 16.7 14.8 29.9 15.0 24.5 18.1 21.7 116.2 51.0 50.0 72.6 34.7 40.1 51.0 53.5 28.8 93.3 77.0 64.1 37.5 126.3 90.6 28.2 82.4 68.4 70.3 60.2 120.3 66.8 66.5 99.9 32.9 53.2 62.6 137.0 51.3 28.2 56.7 71.4 116.6 30.3 65.2 100.9 63.5 78.1 67.0 78.8 110.3 126.4 73.0 109.4 126.1 49.1 81.3 134.1 57.2 27.5 139.9 58.9 52.8 42.5 125.0 47.8 51.4 84.0 18.5 73.6 207.4 43.3 109.8 56.3 121.1 244.9 49.1 149.4 124.8 1.0 11.0 2.3 22.2 27.3 32.0 57.3 32.8 30.3 23.8 55.7 41.3 42.0 4.1 28.6 25.1 62.1 33.9 18.2 23.0 21.7 26.7 30.1 21.8 20.9 22.8 20.1 19.6 17.9 21.3 21.7 26.7 6.4 19.4 48.6 41.3 62.2 37.4 45.5 26.2 32.8 43.8 40.4 41.7 42.9 23.2 62.5 18.8 41.7 25.1 8.5 97.8 42.1 165.0 21.7 56.8 38.7 15.0 30.9 154.3 47.7 56.6 44.3 9.7 19.8 62.1 47.7 24.7 61.4 27.2 127.9 132.8 14.4 16.2 7.9 45.5 215.8 50.7 18.7 37.4 58.1 12.8 28.0 19.6 114.1 116.2 35.8 4.6 58.6 36.2 82.8 1.1 87.9 22.4 27.0 26.3 67.3 50.1 163.4 146.1 21.3 66.1 21.9 30.1 54.1 22.6 27.0 COA4 "CHCHD8, CMC3, E2IG2" ENSG00000181924 "Cytochrome c oxidase assembly factor 4 homolog" Q9NYJ1 11 73872667-73876901 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040126 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Mitochondria" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli fibrillar center" Mitochondria "HPA040126: AB_10795415" "unprognostic (7.30e-2)" "unprognostic (8.69e-2)" "unprognostic (2.09e-1)" "unprognostic (2.60e-2)" "unprognostic (1.87e-1)" "unprognostic (1.40e-2)" "unprognostic (3.64e-3)" "unprognostic (1.49e-1)" "unprognostic (2.22e-2)" "prognostic favorable (3.87e-4)" "unprognostic (1.31e-2)" "unprognostic (3.97e-2)" "prognostic unfavorable (2.14e-4)" "unprognostic (2.51e-1)" "unprognostic (1.89e-1)" "unprognostic (1.25e-1)" "unprognostic (8.17e-2)" 45.1 96.2 46.9 36.8 52.5 25.4 39.0 51.6 52.0 37.1 46.2 44.5 49.0 35.8 32.5 48.0 40.2 40.3 63.1 46.0 49.4 70.4 99.7 31.3 47.3 51.0 50.4 37.8 46.5 49.6 34.2 37.6 51.0 45.1 42.2 15.7 42.7 36.2 72.2 33.1 49.6 32.4 50.6 37.1 41.6 31.6 50.3 32.3 55.7 55.9 36.0 54.6 37.4 56.9 106.4 201.9 80.2 119.0 70.6 86.6 79.3 107.4 75.5 126.0 107.2 147.4 132.5 91.3 214.7 90.2 99.9 105.7 124.2 146.1 98.3 120.6 115.1 156.3 118.1 141.8 130.5 107.2 115.0 109.4 136.1 207.0 136.6 70.9 120.0 87.0 135.3 87.5 118.3 210.8 83.7 168.1 104.3 422.7 205.9 96.2 174.3 244.0 137.5 101.3 72.5 121.3 99.0 110.7 295.3 78.8 162.3 108.0 83.8 102.8 91.7 212.9 142.8 103.3 125.1 313.1 57.0 132.0 121.4 18.5 49.6 12.7 35.9 52.2 47.0 58.1 42.0 37.8 61.1 48.5 44.6 48.2 3.4 43.1 51.4 80.2 47.7 38.6 46.9 52.5 51.6 52.0 46.0 49.4 51.0 50.4 51.0 50.6 50.3 56.9 48.9 35.3 36.0 6.8 48.6 53.5 75.7 89.7 47.8 19.5 64.3 86.1 66.7 85.8 55.5 55.2 22.9 168.8 36.7 97.8 129.1 89.2 37.3 77.2 90.9 49.7 72.6 68.3 3.6 94.9 111.3 54.2 69.3 72.0 62.1 83.9 33.2 184.1 97.5 18.5 5.8 98.6 28.5 44.8 34.2 13.3 55.0 44.7 28.4 2.8 55.2 67.5 49.4 8.5 18.8 98.2 85.1 38.4 47.3 139.5 174.2 266.2 47.1 18.5 6.6 81.6 51.0 78.7 34.2 86.3 51.3 122.3 39.9 150.7 121.2 98.7 COA7 "C1orf163, FLJ12439, RESA1, SELRC1" ENSG00000162377 "Cytochrome c oxidase assembly factor 7 (putative)" Q96BR5 1 52684449-52698347 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028154, HPA029926" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Mitochondria" "HPA028154: AB_10600656, HPA029926: AB_10602173" "unprognostic (1.88e-1)" "unprognostic (1.02e-1)" "unprognostic (1.29e-2)" "prognostic unfavorable (8.55e-4)" "unprognostic (2.30e-2)" "unprognostic (5.12e-2)" "prognostic unfavorable (7.01e-5)" "unprognostic (1.14e-1)" "unprognostic (2.27e-2)" "unprognostic (1.24e-1)" "unprognostic (4.07e-2)" "unprognostic (7.42e-2)" "unprognostic (2.49e-1)" "prognostic favorable (4.35e-4)" "unprognostic (1.18e-1)" "unprognostic (1.96e-1)" "unprognostic (1.52e-1)" 6.8 4.8 5.7 5.4 5.5 3.9 7.3 5.2 6.5 4.6 2.5 7.9 7.7 5.5 4.2 6.3 4.6 3.5 5.5 5.3 5.0 9.6 12.1 3.9 4.0 4.7 4.5 3.7 10.7 5.2 2.5 5.2 4.8 3.6 7.5 4.3 3.3 3.6 16.0 6.5 5.6 5.9 3.9 3.9 5.1 3.2 5.1 2.7 7.1 20.4 4.5 5.5 3.5 5.7 26.0 14.5 13.0 21.1 20.7 17.9 28.6 19.1 15.9 23.4 19.5 18.2 9.0 59.4 12.7 11.4 29.6 19.5 31.9 27.1 30.4 18.4 31.9 49.9 22.5 20.9 25.5 49.7 16.4 19.8 23.5 26.6 33.0 10.3 16.3 16.6 46.5 10.0 17.9 17.3 17.0 25.3 57.7 27.7 40.8 32.9 44.6 43.2 20.7 25.9 29.2 15.4 27.9 35.0 36.3 18.3 20.5 33.4 18.2 18.3 24.0 25.5 26.7 21.2 57.0 27.2 8.5 35.4 15.2 1.6 2.9 0.4 1.1 4.3 1.5 1.8 1.2 1.1 3.0 0.7 1.0 1.1 0.6 1.1 2.2 1.1 0.7 1.6 5.7 5.5 5.2 6.5 5.3 5.0 4.7 4.5 4.8 3.9 5.1 5.7 6.0 6.4 12.4 0.7 4.5 11.5 31.2 7.1 9.6 8.8 6.1 5.2 13.2 10.0 7.1 3.7 4.2 17.1 1.7 11.4 27.4 11.9 0.5 3.2 12.3 8.8 2.4 5.5 1.6 13.3 17.0 7.8 5.1 3.4 0.0 8.0 3.6 13.7 13.7 16.8 2.1 7.0 6.1 4.7 3.5 0.8 7.5 7.0 1.8 1.9 8.7 6.8 4.1 3.5 1.5 11.0 7.0 7.5 9.9 19.3 5.0 20.1 2.6 10.2 6.6 11.4 14.0 4.6 13.0 9.7 12.9 16.6 4.2 10.5 10.5 17.8 COQ3 bA9819.1 ENSG00000132423 "Coenzyme Q3, methyltransferase" Q9NZJ6 6 99369401-99394195 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubiquinone biosynthesis" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 51.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 42.8;Distal tubular cells: 33.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031273, HPA031274" Enhanced Approved Nucleoplasm,Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Mitochondria "HPA031273: AB_10611107, HPA031274: AB_10602176" "unprognostic (1.81e-2)" "unprognostic (2.69e-2)" "unprognostic (1.45e-2)" "unprognostic (4.62e-2)" "unprognostic (2.41e-2)" "unprognostic (2.16e-2)" "unprognostic (1.48e-3)" "unprognostic (1.76e-1)" "unprognostic (3.40e-1)" "unprognostic (8.77e-2)" "unprognostic (9.78e-2)" "unprognostic (1.09e-1)" "prognostic favorable (6.86e-5)" "unprognostic (4.61e-2)" "unprognostic (1.81e-1)" "unprognostic (5.45e-2)" "unprognostic (1.08e-1)" 6.4 10.1 13.4 5.2 14.3 4.6 8.6 14.7 18.0 5.6 13.7 10.7 8.2 5.2 7.6 9.3 5.1 3.5 30.9 13.8 13.9 12.7 15.1 3.5 5.6 13.8 14.0 6.8 6.6 14.2 8.5 3.0 13.9 7.7 12.5 11.9 9.6 8.4 37.3 6.9 6.6 6.3 13.7 6.4 7.4 3.0 13.8 7.9 5.2 51.1 7.1 6.8 6.5 13.7 20.2 11.4 13.5 19.2 8.6 9.6 18.4 17.0 10.5 25.2 29.0 15.9 8.5 19.6 11.1 12.8 16.3 18.3 22.7 26.6 30.6 21.0 29.1 24.1 15.5 17.1 11.3 35.0 9.0 6.1 16.0 14.9 14.9 5.5 15.6 23.8 37.2 14.5 13.6 19.8 15.5 29.0 16.4 19.7 21.7 7.5 13.8 26.1 19.9 17.3 21.0 11.2 11.8 18.0 22.9 9.0 22.1 22.8 5.6 10.9 16.0 17.0 26.4 5.1 10.0 30.9 14.0 33.6 16.4 14.1 2.9 2.4 5.0 6.9 5.8 5.6 6.4 8.1 7.3 2.5 10.5 7.8 0.4 10.1 6.1 4.9 5.2 4.7 13.4 14.3 14.7 18.0 13.8 13.9 13.8 14.0 13.9 13.7 13.8 13.7 4.7 3.2 3.7 6.5 3.9 4.5 6.8 26.1 7.4 8.1 5.0 6.3 42.8 5.7 11.2 3.7 0.0 14.0 2.2 3.7 33.2 11.5 0.5 3.5 4.9 5.5 0.0 8.2 10.6 10.5 13.3 5.9 3.6 2.6 1.3 6.6 3.3 8.6 6.8 6.7 13.2 7.3 24.4 1.3 3.5 0.3 8.1 2.4 5.4 1.0 2.0 13.2 4.1 4.5 7.6 9.2 5.8 6.0 4.7 2.4 5.2 12.0 4.9 8.7 6.6 6.5 10.6 3.6 10.9 8.0 4.3 6.3 3.7 11.1 9.8 4.7 COQ9 "C16orf49, DKFZP434K046" ENSG00000088682 "Coenzyme Q9" O75208 16 57447425-57461270 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubiquinone biosynthesis" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 255.4;tongue: 241.0" "Cell type enhanced" "Detected in all" "Distal tubular cells: 217.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040918 Supported Approved Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" "Mitochondria, Cytosol" "HPA040918: AB_10794154" "unprognostic (9.18e-2)" "unprognostic (3.60e-2)" "unprognostic (2.34e-2)" "unprognostic (1.29e-2)" "unprognostic (2.14e-3)" "unprognostic (2.57e-2)" "unprognostic (1.11e-1)" "unprognostic (3.36e-1)" "unprognostic (2.59e-1)" "unprognostic (9.78e-2)" "unprognostic (2.34e-2)" "unprognostic (1.46e-1)" "prognostic favorable (9.03e-11)" "unprognostic (7.40e-2)" "unprognostic (1.51e-1)" "unprognostic (1.71e-1)" "unprognostic (1.23e-2)" 24.3 44.7 21.7 15.1 22.7 10.6 18.0 23.4 26.1 19.6 38.4 48.6 47.3 16.8 16.6 40.0 24.0 19.4 139.7 21.2 22.1 61.3 53.2 14.4 15.6 21.5 21.8 16.6 27.9 79.7 14.9 16.7 20.7 26.2 38.2 11.8 44.1 28.8 255.4 25.2 41.8 28.3 21.3 12.2 35.3 23.8 24.3 18.7 29.2 241.0 17.3 38.2 21.6 21.7 33.6 67.2 18.3 45.8 36.0 27.3 21.3 31.9 25.3 44.8 24.9 41.2 43.0 40.3 59.0 28.8 34.3 70.5 52.8 56.6 28.3 21.4 49.3 27.7 44.2 66.1 39.8 36.1 44.4 45.6 73.7 35.9 68.1 29.8 51.1 35.6 54.7 18.1 27.4 48.6 30.5 26.8 29.6 74.4 90.6 60.8 58.7 104.8 71.3 37.4 56.3 56.7 108.4 103.8 54.9 16.1 59.4 39.5 34.4 32.4 38.9 34.8 40.4 42.9 29.5 48.0 44.4 51.2 37.3 21.0 28.2 23.0 19.5 36.6 20.1 18.8 16.6 17.1 34.4 19.1 17.7 26.0 8.9 24.0 38.2 21.5 25.5 21.9 21.7 22.7 23.4 26.1 21.2 22.1 21.5 21.8 20.7 21.3 24.3 21.7 17.1 12.8 18.9 37.9 15.7 8.4 17.1 55.3 19.9 16.2 21.7 23.1 79.5 45.8 28.7 25.8 16.7 74.7 14.2 68.8 217.2 53.9 37.9 20.4 17.3 17.3 27.6 21.2 21.2 29.3 25.6 20.7 35.7 18.0 7.0 40.7 18.5 53.6 38.8 20.2 24.0 46.6 83.4 16.3 5.4 28.4 21.1 14.1 28.4 7.5 22.7 29.1 14.4 20.6 14.5 27.2 37.0 20.3 15.9 21.5 90.7 114.1 30.0 24.0 13.1 22.6 19.8 66.0 38.8 37.3 11.2 78.7 12.8 91.2 70.2 18.4 CPNE2 CPN2 ENSG00000140848 "Copine 2" Q96FN4 16 57092583-57148369 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 87.4" "Cell type enhanced" "Detected in many" "Adipocytes: 84.3;Hepatic stellate cells: 82.8;Oligodendrocytes: 86.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041132 Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Mitochondria, Cytosol" "HPA041132: AB_2677316" "unprognostic (1.73e-2)" "unprognostic (3.18e-1)" "unprognostic (1.36e-1)" "unprognostic (4.93e-3)" "unprognostic (1.42e-2)" "unprognostic (1.91e-1)" "unprognostic (2.10e-2)" "unprognostic (9.14e-2)" "unprognostic (2.10e-3)" "unprognostic (8.78e-3)" "unprognostic (2.18e-2)" "unprognostic (1.88e-1)" "unprognostic (3.53e-3)" "unprognostic (8.29e-2)" "unprognostic (1.24e-1)" "unprognostic (7.44e-3)" "unprognostic (1.33e-1)" 35.1 7.3 34.5 12.8 50.2 60.6 24.9 41.1 45.3 36.5 36.9 29.2 6.0 20.7 6.6 15.9 28.0 14.3 15.5 36.7 46.6 14.1 9.4 37.2 11.0 52.9 48.1 10.7 7.3 10.9 7.5 27.9 48.6 14.0 28.3 1.7 10.9 17.1 11.7 11.7 21.2 25.1 39.3 18.2 9.2 16.4 61.0 6.3 15.9 13.5 9.2 16.7 18.5 87.4 23.9 45.1 68.0 38.1 12.0 11.6 11.3 25.4 39.8 56.8 39.5 12.7 27.0 14.2 22.7 38.6 31.4 36.7 27.1 15.1 30.6 17.7 15.9 5.9 17.5 10.7 21.6 4.8 0.6 11.1 16.8 22.3 10.8 42.4 84.5 7.6 16.0 0.5 14.5 11.1 7.2 69.9 15.5 11.6 9.5 88.8 21.3 11.9 37.7 9.0 1.4 27.6 32.3 6.9 19.4 30.5 7.5 94.4 60.3 51.6 27.7 13.1 33.5 3.4 3.0 31.8 33.4 20.6 37.0 0.0 1.5 0.8 0.2 0.4 0.2 0.0 0.1 0.4 0.8 0.0 0.1 0.2 1.5 0.1 0.1 0.0 0.2 0.4 34.5 50.2 41.1 45.3 36.7 46.6 52.9 48.1 48.6 39.3 61.0 87.4 84.3 19.2 7.4 8.1 1.5 2.3 17.1 6.0 7.4 0.4 8.2 6.9 2.3 4.3 5.1 5.5 0.0 0.6 1.4 43.4 5.9 4.7 19.9 33.4 13.8 41.0 3.6 0.8 1.0 4.2 2.9 12.3 1.5 39.3 0.0 26.7 82.8 2.0 23.6 0.0 7.4 13.7 4.1 25.3 7.4 5.9 6.8 12.0 7.2 8.4 10.7 3.6 0.0 17.1 86.3 6.2 25.1 7.5 0.8 14.2 35.4 2.6 9.2 0.0 32.9 9.3 21.7 0.6 2.6 6.2 4.3 0.8 8.4 2.1 18.2 16.3 CREB3L4 "AIbZIP, ATCE1, CREB3, CREB4, hJAL" ENSG00000143578 "CAMP responsive element binding protein 3 like 4" Q8TEY5 1 153967534-153974361 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation, Unfolded protein response" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 106.2" "Cell type enhanced" "Detected in many" "Breast glandular cells: 49.9;Breast myoepithelial cells: 40.1;Intestinal goblet cells: 56.9;Prostatic glandular cells: 49.3" "Group enriched" "Detected in all" 5 "breast cancer: 47.8;endometrial cancer: 28.7;prostate cancer: 109.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 81.8;OE19: 82.7;SK-BR-3: 174.6;T-47d: 139.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA038122 Enhanced Approved "Nucleoplasm,Nuclear membrane,Mitochondria" No No "Cluster 22: NK-cells - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 35: Glandular cells - Unknown function" "Nucleoplasm, Nuclear membrane" Mitochondria "HPA038122: AB_10669516" "unprognostic (1.35e-1)" "unprognostic (4.71e-2)" "unprognostic (8.13e-3)" "prognostic favorable (7.21e-4)" "unprognostic (2.04e-1)" "unprognostic (1.40e-2)" "unprognostic (5.51e-3)" "unprognostic (5.02e-2)" "unprognostic (1.01e-1)" "unprognostic (4.40e-2)" "unprognostic (1.62e-1)" "unprognostic (1.70e-1)" "unprognostic (7.12e-3)" "unprognostic (2.13e-1)" "unprognostic (1.06e-1)" "unprognostic (8.83e-2)" "unprognostic (9.34e-3)" 6.3 8.5 3.5 4.5 3.8 7.6 48.2 4.6 4.7 30.5 4.4 11.5 11.4 12.9 13.0 8.2 19.2 6.7 5.0 3.3 3.5 10.5 14.0 5.8 5.9 3.9 4.1 17.4 13.2 6.7 6.1 6.3 3.7 106.2 15.2 4.9 43.9 7.6 5.6 10.2 9.0 5.7 3.9 7.5 29.3 5.3 3.6 12.0 11.3 5.3 7.4 6.8 6.9 4.7 7.5 10.6 9.8 10.9 6.9 10.0 24.7 6.2 7.2 8.3 7.3 5.1 31.0 13.9 31.7 2.6 6.1 12.0 14.5 9.7 4.5 11.4 5.9 10.3 11.7 8.9 5.6 4.9 8.5 10.9 9.2 7.9 17.9 7.5 7.4 16.5 8.1 16.9 3.8 81.8 9.3 3.8 6.7 82.7 12.7 20.9 10.3 26.1 9.0 5.3 18.5 20.1 6.6 174.6 16.8 12.8 139.9 14.9 4.5 2.5 7.3 5.2 4.9 31.4 17.3 10.6 5.3 8.5 8.2 1.5 2.9 2.2 3.4 1.2 4.5 4.5 1.9 2.4 5.0 4.8 1.8 3.5 0.1 9.4 1.7 5.7 1.8 2.5 3.5 3.8 4.6 4.7 3.3 3.5 3.9 4.1 3.7 3.9 3.6 4.7 7.2 6.4 13.1 3.6 6.2 2.9 13.1 10.1 6.8 5.3 49.9 40.1 2.0 7.2 20.3 1.8 2.1 12.9 5.6 3.6 9.8 14.0 0.4 10.6 5.2 6.9 9.0 8.6 0.4 13.3 17.0 4.8 10.7 13.5 5.7 8.7 4.2 14.2 5.4 0.0 0.4 56.9 6.1 7.5 2.0 0.6 7.2 5.1 5.4 0.0 2.8 6.6 8.2 1.5 2.2 7.9 4.3 2.2 5.3 49.3 4.0 4.1 16.6 8.8 19.7 3.1 5.0 7.4 10.6 6.3 3.0 4.2 4.5 7.6 10.9 7.0 CREBL2 ENSG00000111269 "CAMP responsive element binding protein like 2" O60519 12 12611827-12645108 "Predicted intracellular proteins, Transcription factors" "Cell cycle, Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 130.6" "Cell type enhanced" "Detected in all" "Kupffer cells: 120.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043738 Uncertain Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 5: NTERA-2 - Transcription" "Cluster 4: Macrophages - Innate immune response" Mitochondria "Nucleoplasm, Cytosol" "HPA043738: AB_10795041" "unprognostic (2.87e-2)" "unprognostic (1.15e-1)" "unprognostic (2.32e-1)" "unprognostic (7.51e-2)" "unprognostic (7.38e-2)" "unprognostic (4.51e-1)" "unprognostic (1.44e-1)" "unprognostic (5.92e-2)" "unprognostic (1.10e-1)" "unprognostic (4.12e-2)" "unprognostic (5.82e-3)" "unprognostic (6.73e-2)" "prognostic favorable (2.26e-5)" "unprognostic (6.31e-2)" "unprognostic (1.57e-1)" "unprognostic (3.59e-1)" "unprognostic (1.53e-1)" 39.8 130.6 24.7 30.4 26.3 5.3 31.9 22.8 29.2 26.4 29.5 23.4 23.1 19.0 28.8 17.1 24.6 28.2 22.5 26.2 28.8 49.7 50.1 32.5 37.5 24.6 24.5 37.2 24.7 56.3 32.2 24.2 24.6 28.2 23.8 35.2 26.4 23.0 10.1 24.6 23.6 18.9 24.8 37.5 25.1 20.9 29.1 24.7 44.3 15.6 29.8 28.0 15.1 27.7 12.5 15.9 13.6 15.5 46.9 47.0 26.3 24.0 40.4 17.3 23.7 11.5 17.9 10.8 9.1 29.3 26.2 10.3 20.7 18.4 29.1 61.0 12.6 8.5 15.1 14.2 30.7 12.2 15.2 30.8 32.2 20.3 33.1 58.7 25.7 8.5 8.7 16.5 29.4 20.1 6.4 9.9 40.8 11.9 14.4 8.7 23.6 6.9 33.1 35.7 16.0 18.2 24.4 11.7 43.3 58.5 6.5 13.6 20.8 23.7 15.1 23.7 23.9 13.9 19.7 2.7 28.1 10.3 24.9 1.1 2.5 2.6 1.7 5.6 3.1 0.9 3.4 2.7 2.8 1.1 3.3 2.7 0.4 1.1 2.6 1.4 5.6 1.5 24.7 26.3 22.8 29.2 26.2 28.8 24.6 24.5 24.6 24.8 29.1 27.7 18.0 25.6 26.5 23.5 14.8 22.2 18.6 11.1 18.8 17.5 23.5 15.9 14.6 30.0 12.2 33.1 2.1 18.1 15.7 17.7 41.1 21.6 40.4 14.2 10.4 19.1 30.0 27.8 15.9 21.8 19.3 25.3 17.9 10.6 10.2 12.1 23.2 48.4 39.3 37.0 17.7 16.4 26.4 120.0 83.0 12.1 36.1 58.2 33.8 33.7 45.6 38.0 10.3 28.6 18.6 21.8 15.0 35.3 17.3 29.5 29.3 58.8 19.9 11.8 39.5 13.7 12.4 45.8 20.8 18.0 29.1 27.5 23.3 11.5 17.6 28.1 CREBZF ZF ENSG00000137504 "CREB/ATF bZIP transcription factor" Q9NS37 11 85657990-85682908 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "HeLa: 53.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021526, HPA063652" Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Mitochondria" "HPA021526: AB_2670738, HPA063652: AB_2685075" "unprognostic (1.17e-1)" "unprognostic (1.70e-1)" "unprognostic (1.39e-1)" "unprognostic (1.31e-1)" "unprognostic (1.72e-2)" "unprognostic (6.46e-2)" "unprognostic (2.23e-3)" "unprognostic (2.21e-1)" "unprognostic (1.17e-2)" "unprognostic (1.19e-2)" "unprognostic (4.51e-2)" "unprognostic (1.04e-3)" "unprognostic (2.23e-3)" "unprognostic (1.73e-2)" "unprognostic (7.68e-2)" "unprognostic (4.34e-2)" "unprognostic (2.38e-3)" 17.1 12.4 9.8 12.9 11.1 9.7 16.8 18.3 15.4 15.9 11.3 12.8 14.1 21.3 12.2 10.1 15.1 10.3 8.2 10.1 9.9 8.8 10.8 15.4 18.7 10.6 10.0 21.7 14.8 11.8 8.7 13.2 11.1 12.9 13.7 27.9 16.4 10.2 9.9 17.2 16.4 10.3 10.5 17.2 12.7 6.1 10.3 13.6 16.3 6.8 15.3 12.1 14.9 13.5 5.6 12.4 18.4 7.6 8.4 8.8 13.7 9.8 6.0 8.4 11.0 15.6 22.5 16.4 9.1 5.8 22.1 19.6 12.7 6.2 14.1 9.3 11.9 14.9 53.1 7.2 5.7 14.1 8.0 7.8 12.2 8.5 11.8 11.5 5.3 10.8 11.7 18.6 10.1 7.9 12.0 27.5 6.8 16.3 8.7 19.2 15.7 10.1 9.2 10.7 14.5 12.4 12.6 19.3 4.2 11.6 20.8 20.8 6.3 17.4 10.7 24.3 11.0 6.4 7.6 16.8 4.1 10.4 10.9 0.3 0.1 0.1 0.4 0.1 0.7 0.2 0.3 0.3 0.2 0.2 0.4 0.4 0.2 0.4 0.3 0.2 0.6 0.1 9.8 11.1 18.3 15.4 10.1 9.9 10.6 10.0 11.1 10.5 10.3 13.5 30.3 19.2 21.5 58.1 41.9 41.3 21.6 12.4 31.3 97.5 35.1 20.6 13.9 17.2 17.9 22.0 91.8 16.9 53.1 30.0 9.8 13.2 34.5 27.6 31.1 25.1 39.4 30.1 57.6 8.6 14.9 34.7 46.9 34.0 22.2 64.3 23.2 29.5 9.9 90.9 60.7 23.8 10.2 19.2 27.3 16.6 30.7 15.6 33.8 25.3 24.8 47.9 46.4 56.8 114.5 9.2 22.8 33.4 39.1 29.5 29.8 8.0 22.5 113.5 13.1 34.6 30.9 27.4 11.4 27.7 41.3 14.4 43.0 51.9 25.7 26.5 CSPG5 NGC ENSG00000114646 "Chondroitin sulfate proteoglycan 5" O95196 3 47562238-47580792 "Predicted membrane proteins" "Differentiation, Growth regulation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 18 "brain: 83.2;choroid plexus: 65.2;retina: 28.3" "Group enriched" "Detected in some" 4 "Astrocytes: 67.6;Muller glia cells: 94.7;Oligodendrocyte precursor cells: 233.7" "Cancer enriched" "Detected in many" 19 "glioma: 48.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 32.6;HEK 293: 8.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049529, HPA067818, HPA071779" Enhanced Approved Nucleoplasm,Mitochondria No No "Cluster 65: Brain - Ion transport" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm Mitochondria "HPA049529: AB_2680805, HPA067818: AB_2685905, HPA071779: AB_2686446" "unprognostic (2.68e-1)" "unprognostic (2.11e-1)" "unprognostic (8.87e-2)" "unprognostic (3.12e-2)" "unprognostic (2.88e-1)" "unprognostic (7.66e-2)" "unprognostic (5.05e-4)" "unprognostic (1.40e-1)" "unprognostic (3.82e-1)" "prognostic favorable (2.14e-4)" "unprognostic (1.17e-1)" "unprognostic (1.13e-1)" "unprognostic (3.41e-4)" "unprognostic (8.08e-2)" "unprognostic (1.01e-1)" "unprognostic (1.43e-1)" "unprognostic (2.10e-1)" 0.9 0.8 58.3 0.2 62.4 0.1 0.6 33.6 83.2 0.3 65.2 1.1 0.0 0.3 0.1 0.3 0.3 0.1 0.5 62.5 49.7 0.2 0.2 3.2 0.2 41.2 45.6 0.2 0.3 0.3 1.7 0.8 45.8 0.4 0.2 28.3 0.3 0.0 0.5 1.1 0.3 0.4 37.0 0.0 0.4 1.9 48.0 0.1 0.4 0.0 0.1 0.1 0.2 46.1 0.3 1.7 32.6 5.7 0.6 0.0 0.9 0.6 0.1 1.2 0.3 0.3 2.0 0.1 2.5 0.1 2.4 0.5 2.7 0.3 0.3 0.0 8.8 0.5 1.4 0.0 0.0 0.4 1.4 0.0 1.1 0.1 0.0 0.9 0.1 1.1 6.6 0.3 0.1 1.5 0.2 0.4 3.1 2.4 3.3 0.5 0.2 0.7 1.4 1.1 3.4 1.5 2.1 4.1 0.1 0.9 1.6 3.1 0.3 0.1 6.5 0.1 1.9 0.8 0.8 0.0 0.5 0.7 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 58.3 62.4 33.6 83.2 62.5 49.7 41.2 45.6 45.8 37.0 48.0 46.1 0.7 3.2 2.0 67.6 0.1 0.8 0.1 0.0 0.0 28.6 2.2 1.8 1.3 0.0 0.0 0.0 6.2 0.2 0.0 0.5 0.0 0.2 2.0 0.6 0.6 0.3 1.8 0.0 18.6 0.0 0.2 0.5 0.0 2.0 0.0 6.1 0.0 0.5 0.2 6.7 25.0 0.3 0.0 0.0 0.2 0.6 0.3 0.2 0.0 7.5 0.0 94.7 0.0 233.7 9.9 0.4 0.1 0.0 0.0 0.2 0.0 0.1 0.0 22.7 0.0 0.8 0.8 13.5 3.3 0.0 0.6 0.1 0.2 0.2 0.4 0.1 CTDSP2 "OS4, PSR2, SCP2" ENSG00000175215 "CTD small phosphatase 2" O14595 12 57819927-57846729 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 5 "RH-30: 1208.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052607 Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Mitochondria "HPA052607: AB_2681883" "unprognostic (7.09e-2)" "unprognostic (2.45e-1)" "unprognostic (1.84e-2)" "unprognostic (3.07e-2)" "unprognostic (4.39e-1)" "unprognostic (5.57e-2)" "unprognostic (1.05e-3)" "unprognostic (2.45e-2)" "unprognostic (1.04e-1)" "unprognostic (1.06e-2)" "unprognostic (1.12e-1)" "unprognostic (4.15e-1)" "unprognostic (7.38e-3)" "unprognostic (5.50e-2)" "unprognostic (6.50e-2)" "unprognostic (2.18e-1)" "unprognostic (3.11e-1)" 90.9 82.5 66.8 65.4 80.0 45.7 81.8 79.7 69.3 84.0 61.0 108.9 54.3 96.4 51.4 67.0 89.9 64.7 72.4 64.6 63.0 66.2 58.8 113.9 66.1 90.7 80.6 107.3 119.4 68.2 40.3 94.3 76.5 70.1 83.2 30.1 109.1 82.8 122.3 88.9 77.0 94.8 71.4 75.5 89.9 32.3 74.3 104.8 68.1 102.8 77.5 85.2 71.8 83.4 83.1 35.4 165.6 105.8 145.6 248.8 55.0 87.4 165.1 85.2 75.4 45.6 131.5 101.3 98.1 187.5 33.2 64.8 70.0 85.3 88.8 34.2 29.7 140.3 54.4 37.0 135.4 64.3 78.3 239.7 88.9 77.3 65.1 181.9 135.0 60.6 74.5 172.9 43.4 38.2 69.1 38.3 84.3 52.5 44.4 91.0 1208.7 133.2 66.2 118.6 31.1 68.3 122.1 69.4 105.3 100.2 125.8 110.4 109.3 75.0 80.8 85.6 31.5 51.4 59.6 120.3 84.4 58.5 59.7 12.6 9.1 14.4 6.1 8.5 7.2 6.6 8.6 7.1 8.7 6.0 9.8 7.6 17.2 8.2 7.6 7.2 6.2 7.4 66.8 80.0 79.7 69.3 64.6 63.0 90.7 80.6 76.5 71.4 74.3 83.4 50.9 73.7 42.7 31.3 28.5 67.6 45.2 34.6 51.8 19.0 51.2 36.6 34.0 78.6 27.6 47.8 16.7 43.7 48.8 151.1 15.6 72.9 52.2 33.4 51.2 59.3 48.7 50.1 15.8 135.0 41.4 51.0 20.4 50.1 24.7 44.2 86.4 59.1 42.3 20.2 11.0 39.4 16.2 76.1 43.5 151.9 51.9 39.5 42.7 16.9 81.9 44.4 42.2 17.6 27.9 105.8 49.3 48.5 30.3 70.4 57.5 30.6 18.4 11.2 72.3 49.2 53.3 6.3 25.1 39.6 76.1 56.2 34.3 34.8 37.3 99.2 CTPS2 ENSG00000047230 "CTP synthase 2" Q9NRF8 X 16587999-16712936 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Pyrimidine biosynthesis" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 35.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017437, HPA075930" Approved Approved Mitochondria,Cytosol NA NA 40000 "Cluster 27: Non-specific - Gene expression" "Cluster 37: Intestine - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Mitochondria, Cytosol" "HPA017437: AB_1847326, HPA075930: " "unprognostic (1.40e-1)" "unprognostic (6.69e-2)" "unprognostic (3.37e-2)" "unprognostic (7.38e-2)" "unprognostic (1.05e-2)" "unprognostic (2.11e-1)" "prognostic unfavorable (2.37e-5)" "unprognostic (6.57e-3)" "unprognostic (8.52e-2)" "unprognostic (4.31e-3)" "unprognostic (4.43e-1)" "unprognostic (1.89e-2)" "unprognostic (7.22e-2)" "unprognostic (6.04e-2)" "unprognostic (8.93e-2)" "unprognostic (5.04e-2)" "prognostic favorable (4.56e-4)" 5.5 7.0 5.6 4.3 7.2 6.9 10.4 7.6 6.3 9.5 6.0 8.1 12.3 10.3 6.7 5.1 9.0 6.8 4.4 5.1 6.8 6.0 7.5 6.5 6.6 8.0 6.3 13.2 9.2 12.1 4.0 6.6 8.0 9.5 9.5 9.9 7.4 7.0 4.3 7.1 10.3 7.4 6.5 4.4 8.3 2.0 6.3 6.1 6.8 4.6 8.2 6.2 6.2 9.4 13.7 12.6 20.3 16.9 10.1 7.6 0.2 7.3 6.2 12.1 11.0 13.0 14.2 0.4 23.2 7.9 11.0 11.0 28.9 13.9 14.3 0.1 18.9 7.9 17.0 19.2 5.3 5.7 0.2 8.4 4.7 11.3 9.5 13.6 16.5 0.3 11.1 0.5 11.2 18.9 0.2 4.6 34.7 5.2 14.6 0.3 11.6 4.4 13.3 15.5 12.5 22.8 23.5 1.8 14.2 21.9 32.8 16.2 10.3 6.2 3.3 16.5 6.6 0.3 0.2 45.6 5.0 4.9 7.0 0.1 0.6 0.5 0.4 0.3 0.9 0.6 0.8 0.5 1.3 0.5 0.6 0.6 0.0 1.7 2.7 0.9 0.9 0.6 5.6 7.2 7.6 6.3 5.1 6.8 8.0 6.3 8.0 6.5 6.3 9.4 6.7 9.6 6.7 13.4 3.4 3.2 6.0 4.8 4.6 5.4 8.0 6.5 6.0 8.6 8.9 5.5 0.0 3.5 4.4 5.5 3.9 9.8 4.0 7.2 6.4 5.4 11.3 3.8 10.4 9.4 7.9 5.9 6.1 9.0 6.3 9.1 6.8 7.9 5.3 6.7 18.2 7.5 4.1 4.4 2.7 8.6 9.0 3.3 8.8 24.4 6.0 4.4 1.0 26.2 35.5 11.3 9.0 4.1 4.0 3.9 19.2 3.0 6.1 5.1 6.6 4.1 6.6 0.1 0.3 3.7 3.8 1.5 2.7 4.3 8.8 5.8 CWC15 "AD002, C11orf5, Cwf15, HSPC148" ENSG00000150316 "CWC15 spliceosome associated protein homolog" Q9P013 11 94962620-94973586 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 883.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039878 Supported Approved "Nuclear speckles,Mitochondria" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 29: Early spermatids - Spermatogenesis" "Nuclear speckles, Mitochondria" "HPA039878: AB_2676722" "unprognostic (1.97e-1)" "unprognostic (5.51e-2)" "unprognostic (1.66e-2)" "unprognostic (8.64e-2)" "unprognostic (3.81e-1)" "unprognostic (6.85e-2)" "unprognostic (1.29e-1)" "unprognostic (1.52e-1)" "unprognostic (4.84e-3)" "prognostic favorable (9.75e-4)" "unprognostic (4.69e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (1.91e-5)" "unprognostic (1.44e-1)" "unprognostic (1.34e-1)" "prognostic favorable (7.17e-4)" "unprognostic (5.23e-2)" 23.1 21.8 37.3 14.2 37.5 32.3 30.5 38.5 46.3 22.5 33.9 20.4 16.0 20.8 34.1 23.6 21.3 13.9 35.0 37.1 39.1 31.2 37.6 17.3 25.1 38.3 39.8 27.0 22.4 25.9 15.7 25.6 38.5 19.9 19.4 25.2 27.0 19.7 68.7 18.1 18.3 17.4 38.6 18.9 21.7 40.0 38.0 30.8 25.1 60.1 24.4 22.0 20.7 39.4 27.1 16.5 63.3 32.3 54.4 50.1 33.0 40.1 52.4 59.9 51.0 80.6 62.4 40.3 76.2 51.1 41.2 28.9 33.8 47.3 66.3 50.7 30.5 51.3 20.5 40.0 45.3 65.9 31.8 47.9 54.1 36.7 54.0 50.2 59.5 44.3 58.2 37.2 56.1 29.4 65.2 87.6 32.0 66.6 42.9 43.7 38.2 44.2 61.1 30.2 35.2 28.8 42.0 44.7 35.9 53.3 72.1 50.8 35.8 44.4 35.2 60.7 41.0 16.9 41.2 57.4 25.5 73.4 44.8 45.9 22.6 33.9 23.6 28.1 32.3 28.7 31.3 29.0 29.6 25.2 29.7 30.7 27.4 26.8 35.9 28.7 34.4 23.7 37.3 37.5 38.5 46.3 37.1 39.1 38.3 39.8 38.5 38.6 38.0 39.4 67.1 73.7 63.9 12.4 69.3 59.3 84.6 150.1 54.7 59.3 56.1 80.0 170.3 92.9 112.2 51.5 14.6 146.7 75.5 62.4 221.1 122.2 883.6 57.7 60.9 74.3 28.4 96.2 15.4 144.0 126.3 80.0 42.8 57.9 104.4 68.6 96.0 121.3 128.7 40.4 17.0 68.3 83.4 69.5 62.4 203.6 112.8 68.8 71.2 14.0 109.1 142.6 104.0 13.0 21.5 125.7 85.4 92.9 59.2 90.9 99.0 245.9 89.1 59.1 138.1 72.5 98.8 267.7 196.2 80.2 63.9 119.3 71.3 69.9 65.2 70.9 CYB5R1 "humb5R2, NQO3A2" ENSG00000159348 "Cytochrome b5 reductase 1" Q9UHQ9 1 202961873-202967275 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 605.2" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 187.2;Extravillous trophoblasts: 196.5;Syncytiotrophoblasts: 293.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HaCaT: 187.3;hTCEpi: 188.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010641, HPA014147" Enhanced Approved Mitochondria,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 38: Extravillous trophoblasts - Unknown function" Mitochondria Cytosol "HPA010641: AB_1078600, HPA014147: AB_1847370" "unprognostic (6.36e-2)" "unprognostic (8.51e-2)" "unprognostic (1.16e-2)" "prognostic favorable (1.14e-4)" "unprognostic (1.86e-2)" "unprognostic (4.34e-2)" "unprognostic (8.46e-2)" "unprognostic (1.28e-1)" "unprognostic (4.03e-1)" "unprognostic (1.03e-1)" "unprognostic (5.79e-2)" "unprognostic (2.89e-1)" "unprognostic (1.73e-2)" "unprognostic (2.33e-1)" "unprognostic (6.14e-2)" "unprognostic (2.37e-3)" "unprognostic (1.69e-1)" 38.6 57.3 37.4 23.0 38.8 19.7 43.7 41.1 40.5 49.7 57.3 35.7 19.3 41.2 131.4 61.6 68.2 27.2 154.8 38.3 48.0 64.5 50.2 44.0 25.2 45.4 49.4 41.7 45.1 82.9 46.1 66.6 55.7 41.1 21.2 34.3 56.9 40.0 605.2 123.8 25.7 37.5 39.9 39.1 92.8 50.7 41.4 40.1 40.5 308.0 38.8 52.7 45.8 43.6 34.8 21.3 18.3 37.7 166.0 37.9 178.5 68.3 63.4 43.2 38.4 17.5 39.9 21.5 56.5 68.1 24.0 187.3 14.9 58.0 28.2 31.2 37.8 12.4 24.0 20.4 59.7 10.5 29.6 61.2 188.3 47.5 25.8 36.4 28.9 25.8 37.0 37.6 157.8 40.4 13.6 9.5 12.1 31.0 40.1 21.9 87.6 45.7 41.1 40.8 15.7 19.1 38.0 124.0 57.4 39.4 57.7 23.4 28.5 49.0 20.8 18.7 38.3 34.9 44.5 10.0 53.6 16.2 37.1 24.4 56.7 46.6 27.4 42.6 36.3 23.4 30.9 28.9 37.6 35.0 41.9 29.6 46.0 32.2 29.4 25.9 34.2 52.6 37.4 38.8 41.1 40.5 38.3 48.0 45.4 49.4 55.7 39.9 41.4 43.6 33.0 22.4 29.8 10.1 15.5 187.2 38.5 89.5 42.1 21.0 46.1 41.9 119.3 37.1 60.5 29.5 29.2 171.1 15.8 10.6 7.9 38.3 5.0 58.7 17.3 30.0 19.2 30.7 8.9 48.3 196.5 28.9 31.6 34.9 28.5 13.6 32.9 44.6 63.5 10.1 11.3 10.8 105.8 45.4 29.7 8.6 29.8 39.5 64.0 8.4 20.9 65.9 11.3 11.6 8.1 72.8 11.3 31.2 12.5 25.8 16.0 38.9 75.9 35.0 13.1 49.1 30.0 23.0 4.3 40.6 157.4 293.5 19.5 27.9 14.7 48.2 CYC1 UQCR4 ENSG00000179091 "Cytochrome c1" P08574 8 144095039-144097525 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 730.0;tongue: 724.9" "Cell type enhanced" "Detected in all" "Distal tubular cells: 817.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 1125.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001247 Supported Approved Mitochondria NA NA 45000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA001247: AB_1078602" "unprognostic (3.07e-2)" "unprognostic (1.79e-1)" "unprognostic (1.65e-1)" "unprognostic (3.66e-2)" "unprognostic (1.25e-1)" "unprognostic (6.52e-2)" "unprognostic (1.39e-1)" "unprognostic (3.92e-3)" "unprognostic (6.23e-2)" "unprognostic (1.98e-1)" "unprognostic (2.26e-1)" "unprognostic (2.15e-1)" "prognostic favorable (5.89e-6)" "unprognostic (6.03e-2)" "unprognostic (1.83e-1)" "unprognostic (2.13e-1)" "unprognostic (3.13e-2)" 84.7 173.2 92.1 62.4 97.2 104.4 72.7 115.4 103.8 71.4 102.4 162.6 171.2 75.9 35.7 155.5 67.8 39.5 527.7 92.3 105.3 152.6 180.4 56.7 55.8 99.8 96.9 63.6 101.2 163.3 58.2 45.8 103.1 67.8 111.0 42.0 104.4 70.0 730.0 106.5 127.5 59.9 94.9 70.1 139.6 38.9 106.9 63.4 64.8 724.9 61.0 92.0 86.5 99.6 172.0 381.4 98.9 208.4 80.5 88.5 189.6 96.7 116.7 240.2 156.9 269.4 208.2 241.0 210.8 129.8 116.2 247.3 217.9 191.2 89.8 148.2 289.2 259.7 306.5 250.4 143.1 154.7 162.5 129.4 234.9 153.2 301.4 80.6 141.3 163.7 240.4 208.2 127.7 616.8 292.0 143.5 115.1 476.8 1125.5 253.7 132.4 422.1 199.7 273.0 263.3 117.2 267.8 365.7 200.0 54.0 302.5 233.2 108.8 152.1 321.6 169.6 299.7 229.1 179.7 183.8 193.2 261.9 198.4 185.7 340.4 95.7 131.6 360.4 139.8 208.7 108.1 141.5 444.1 180.3 104.9 134.6 32.7 187.8 278.8 251.0 158.2 397.1 92.1 97.2 115.4 103.8 92.3 105.3 99.8 96.9 103.1 94.9 106.9 99.6 77.0 19.2 29.3 23.5 94.0 156.1 191.9 394.8 62.6 113.6 110.7 102.6 402.3 181.6 156.0 79.1 81.3 263.6 61.7 516.1 817.8 239.9 81.2 59.1 68.1 88.0 146.4 130.6 14.4 289.1 257.1 102.8 144.8 60.2 59.7 89.2 62.4 239.4 246.3 87.5 21.6 390.4 272.6 104.8 139.4 88.6 88.9 101.4 179.7 12.2 208.4 115.2 92.7 12.1 17.5 290.6 332.5 90.7 149.9 237.9 570.0 468.6 86.1 100.9 72.3 109.4 250.6 83.1 116.7 212.9 163.7 236.8 63.8 197.5 602.6 258.3 CYP11B1 "CPN1, CYP11B, FHI, P450C11" ENSG00000160882 "Cytochrome P450 family 11 subfamily B member 1" P15538 8 142872356-142879846 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroidogenesis" "Monooxygenase, Oxidoreductase" "Congenital adrenal hyperplasia, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 877 "adrenal gland: 3686.5" "Group enriched" "Detected in some" 113 "Early spermatids: 53.3;Late spermatids: 83.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049171, HPA049565, HPA056348, HPA057752" Supported Approved Mitochondria NA NA "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "HPA049171: AB_2680661, HPA049565: , HPA056348: AB_2683104, HPA057752: AB_2683516" 0.2 3686.5 0.1 0.9 0.6 0.0 0.1 0.0 0.1 0.2 0.5 0.2 0.0 0.2 0.0 0.4 0.2 0.0 0.4 0.3 0.0 0.9 0.5 0.3 0.0 0.1 0.1 0.3 0.5 0.0 0.4 0.0 0.0 0.3 0.0 0.0 1.4 0.0 0.2 0.2 0.2 0.0 0.0 0.3 0.4 4.2 0.0 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 83.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CYP24A1 "CP24, CYP24, P450-CC24" ENSG00000019186 "Cytochrome P450 family 24 subfamily A member 1" Q07973 20 54153446-54173986 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "endometrium 1: 14.9;kidney: 35.3;lymphoid tissue: 10.5;placenta: 10.0;urinary bladder: 28.7" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 48.3;Basal respiratory cells: 142.7;Basal squamous epithelial cells: 74.0;Club cells: 47.0;Proximal tubular cells: 61.3;Urothelial cells: 36.7" "Cancer enhanced" "Detected in many" "lung cancer: 18.3;urothelial cancer: 21.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "A549: 411.5;Hep G2: 122.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA022261, HPA063771" Enhanced Approved "Nucleoplasm,Plasma membrane,Mitochondria" NA Yes "Cluster 39: Non-specific - mRNA processing" "Cluster 7: Kidney - Transmembrane transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Mitochondria" "Plasma membrane" "HPA022261: AB_1847427, HPA063771: AB_2685120" "unprognostic (1.19e-7)" "unprognostic (1.73e-1)" "unprognostic (2.24e-2)" "unprognostic (7.69e-3)" "unprognostic (3.30e-1)" "unprognostic (2.30e-2)" "unprognostic (1.11e-2)" "unprognostic (2.12e-1)" "unprognostic (2.09e-2)" "unprognostic (5.37e-3)" "unprognostic (1.23e-1)" "unprognostic (6.05e-2)" "unprognostic (5.98e-2)" "unprognostic (1.36e-1)" "unprognostic (4.38e-2)" "unprognostic (2.12e-1)" 0.0 0.0 0.2 0.4 0.4 0.0 3.7 0.0 0.3 1.7 0.0 0.0 0.1 14.9 0.2 3.8 0.2 0.0 0.0 0.1 1.8 35.3 0.4 0.7 0.2 0.4 2.0 0.0 0.0 0.0 0.2 10.0 0.3 2.9 0.0 0.0 0.3 2.0 0.0 0.9 0.0 0.2 0.1 0.0 0.0 0.0 0.6 0.2 1.3 0.0 10.5 28.7 1.3 0.2 0.5 411.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 12.6 0.0 3.2 0.0 0.9 15.8 0.0 0.1 0.1 0.0 0.0 0.0 6.5 122.6 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.7 0.0 7.0 1.3 0.0 2.6 0.6 0.0 0.1 0.1 0.0 0.0 0.0 16.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.3 0.1 1.8 0.4 2.0 0.3 0.1 0.6 0.2 0.0 0.0 0.0 0.0 1.3 22.8 48.3 142.7 74.0 0.0 11.0 8.6 0.4 0.0 47.0 0.0 0.0 0.1 0.1 0.1 5.9 0.1 0.0 0.7 0.5 0.3 0.0 0.0 0.2 0.0 0.1 2.0 0.0 4.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 12.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 9.8 0.0 61.3 13.1 0.0 0.0 0.0 0.6 0.0 0.0 3.3 19.6 0.1 0.1 0.0 0.2 36.7 CYP27A1 "CP27, CTX, CYP27" ENSG00000135929 "Cytochrome P450 family 27 subfamily A member 1" Q02318 2 218781749-218815293 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "liver: 594.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 404.3;Hofbauer cells: 148.9;Proximal enterocytes: 206.3" "Group enriched" "Detected in all" 4 "liver cancer: 176.9;melanoma: 85.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 151.5;neutrophil: 126.3" "Group enriched" "Detected in many" 21 "granulocytes: 126.3;monocytes: 151.5" "Cell line enhanced" "Detected in many" "Hep G2: 299.6;HSkMC: 54.7;RPTEC TERT1: 78.5;SK-MEL-30: 103.6;WM-115: 42.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059155 Enhanced Approved Mitochondria,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Mitochondria Cytosol "HPA059155: AB_2683933" "prognostic favorable (1.05e-4)" "unprognostic (4.21e-2)" "unprognostic (2.34e-1)" "unprognostic (1.83e-3)" "unprognostic (3.71e-3)" "unprognostic (1.31e-2)" "prognostic favorable (8.62e-6)" "unprognostic (6.04e-2)" "unprognostic (1.73e-1)" "unprognostic (4.04e-1)" "unprognostic (1.25e-3)" "unprognostic (8.76e-3)" "unprognostic (1.09e-3)" "unprognostic (1.08e-1)" "unprognostic (7.51e-2)" "unprognostic (1.64e-1)" "unprognostic (1.36e-1)" 23.1 50.3 45.2 15.7 59.0 1.3 21.8 57.0 59.3 27.6 75.6 27.6 77.8 19.8 11.6 11.9 34.0 19.1 30.7 42.2 49.3 46.4 594.4 71.7 24.6 63.0 56.1 32.6 8.3 18.5 29.6 6.2 62.7 41.8 20.7 22.5 40.4 29.5 37.9 17.5 81.9 13.2 50.6 13.0 13.8 12.6 58.8 23.6 12.6 49.2 28.0 24.3 23.2 69.2 0.2 0.0 2.7 0.2 4.6 3.3 0.4 1.9 11.7 3.9 7.8 13.7 0.8 0.0 4.3 7.6 0.2 0.1 0.0 0.0 1.7 1.4 1.0 0.0 0.4 299.6 16.2 0.4 0.3 54.7 0.5 0.1 0.0 12.8 5.9 0.0 0.3 0.1 8.3 0.0 0.0 0.2 2.3 0.3 0.5 0.1 2.4 0.5 78.5 0.2 0.2 0.2 0.1 0.0 103.6 2.4 1.6 2.2 5.9 0.0 0.2 0.1 6.0 0.0 0.0 0.1 0.1 0.3 42.9 0.0 151.5 0.4 0.2 17.1 0.3 0.7 0.2 0.5 6.5 0.0 0.1 0.0 126.3 0.0 1.2 0.8 0.0 44.1 45.2 59.0 57.0 59.3 42.2 49.3 63.0 56.1 62.7 50.6 58.8 69.2 10.6 3.2 28.9 33.6 0.9 5.2 52.4 8.5 21.6 15.3 12.7 18.8 5.1 17.2 11.3 3.7 27.1 0.7 0.5 37.0 9.8 12.1 1.0 12.6 4.3 10.3 24.5 8.4 2.2 12.0 0.7 35.4 2.6 14.8 2.5 1.9 19.6 404.3 148.9 10.1 3.9 20.0 4.1 18.2 5.1 1.0 47.5 104.3 49.8 15.0 92.4 28.7 0.0 26.7 108.5 9.7 44.0 26.7 0.0 43.3 206.3 76.9 21.4 14.1 0.0 12.8 7.2 0.7 0.1 3.2 3.1 1.2 2.3 1.2 30.3 20.4 CYP2E1 CYP2E ENSG00000130649 "Cytochrome P450 family 2 subfamily E member 1" P05181 10 133520406-133561220 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 309 "liver: 10379.8" "Cell type enriched" "Detected in many" 58 "Hepatocytes: 6272.7" "Cancer enriched" "Detected in some" 278 "liver cancer: 265.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 2.5;myeloid DC: 6.2" "Group enriched" "Detected in many" 16 "dendritic cells: 6.2;T-cells: 2.5" "Cell line enhanced" "Detected in many" "HaCaT: 11.0;HL-60: 8.9;HMC-1: 8.9;NB-4: 24.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA009128, HPA029564" Enhanced Approved "Endoplasmic reticulum,Mitochondria" "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 24: NB-4 - Immune response" "Cluster 2: Hepatocytes - Metabolism" "Endoplasmic reticulum, Mitochondria" "HPA009128: AB_1078613, HPA029564: AB_10602213" "unprognostic (6.32e-2)" "unprognostic (1.51e-2)" "unprognostic (3.83e-5)" "unprognostic (1.27e-1)" "unprognostic (3.37e-2)" "unprognostic (1.26e-1)" "unprognostic (2.92e-3)" "unprognostic (6.36e-3)" "unprognostic (2.41e-2)" "unprognostic (1.49e-1)" "unprognostic (1.63e-1)" "unprognostic (3.21e-2)" "unprognostic (1.70e-4)" "unprognostic (1.72e-1)" "unprognostic (8.36e-2)" "unprognostic (3.78e-1)" "unprognostic (9.59e-2)" 2.8 2.9 5.4 0.6 5.4 0.8 3.0 9.1 7.5 4.9 3.0 5.0 1.4 4.5 8.3 16.7 5.5 2.5 2.1 5.5 5.5 9.1 10379.8 2.6 2.0 6.1 5.5 4.1 12.4 0.6 4.1 1.4 6.7 5.3 1.2 11.5 3.6 6.1 2.8 13.8 2.2 2.2 5.0 7.2 6.7 3.7 6.3 1.7 4.0 0.9 33.6 3.5 3.2 7.5 0.1 0.0 0.3 1.0 3.5 1.9 0.7 1.6 4.5 0.0 0.3 0.0 2.7 1.4 0.2 0.5 0.0 11.0 0.0 0.2 0.4 0.3 1.5 1.8 0.2 1.3 0.6 8.9 8.9 1.0 0.2 0.0 0.7 1.9 0.0 3.1 0.6 0.4 1.0 0.7 0.6 24.0 6.4 4.3 0.4 0.4 6.1 0.0 2.0 0.0 0.0 0.0 4.2 0.0 0.6 0.2 0.3 0.9 0.0 1.4 0.4 2.3 1.0 2.2 1.0 3.0 1.5 7.4 0.1 0.0 0.0 0.0 0.0 0.0 2.5 0.0 1.1 0.6 6.2 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.2 5.4 5.4 9.1 7.5 5.5 5.5 6.1 5.5 6.7 5.0 6.3 7.5 0.8 0.0 1.1 5.5 9.2 2.3 0.2 0.7 0.6 5.7 0.6 0.5 2.8 48.6 1.9 0.0 2.1 0.0 0.4 0.1 0.0 1.6 2.1 0.6 0.8 4.6 0.0 67.6 6.7 1.3 0.1 1.1 1.5 0.5 1.3 0.7 67.1 6272.7 0.0 8.4 5.3 0.0 0.0 108.0 2.8 2.1 1.5 0.3 0.0 1.9 0.4 0.7 0.0 2.0 2.2 3.2 0.0 2.6 0.3 0.6 0.0 0.6 2.2 5.8 0.0 0.2 0.6 4.1 4.2 2.0 7.5 0.1 5.7 0.2 0.0 0.0 DAND5 "CER2, CKTSF1B3, Coco, DANTE, DTE, FLJ38607, GREM3" ENSG00000179284 "DAN domain BMP antagonist family member 5" Q8N907 19 12965159-12974760 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "heart muscle: 8.5" "Cell type enriched" "Detected in some" 7 "Cardiomyocytes: 17.1" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "neutrophil: 1.5" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 16 "SH-SY5Y: 19.8" "Not detected" "Not detected" "HPA043493, HPA049472" Uncertain Approved Mitochondria "Secreted in other tissues" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA043493: AB_2732505, HPA049472: AB_2680781" "unprognostic (1.18e-2)" "unprognostic (4.63e-2)" "unprognostic (7.51e-2)" "unprognostic (4.63e-2)" "unprognostic (3.82e-2)" "unprognostic (8.71e-2)" "unprognostic (2.29e-2)" "unprognostic (3.18e-1)" "unprognostic (5.95e-3)" "unprognostic (7.27e-3)" "unprognostic (8.17e-2)" "unprognostic (2.15e-1)" "unprognostic (2.48e-10)" "unprognostic (4.43e-1)" "unprognostic (2.48e-2)" "unprognostic (6.77e-2)" "unprognostic (1.37e-1)" 0.1 0.9 0.4 0.1 0.4 0.7 0.3 0.9 0.4 0.1 1.6 2.0 0.2 0.1 0.2 0.1 0.1 0.3 8.5 0.4 0.3 0.1 0.0 0.1 0.1 0.5 0.2 0.1 0.2 0.8 0.1 0.0 0.7 0.1 0.3 0.7 0.4 0.0 0.1 0.3 0.3 0.3 0.2 0.0 0.3 0.3 0.5 0.1 0.2 0.2 0.0 0.1 0.0 0.8 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.2 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.1 0.4 0.0 0.8 0.3 0.0 0.0 0.2 0.2 0.0 0.3 0.0 0.2 0.0 0.7 0.4 1.2 0.0 0.4 0.3 0.1 0.2 0.0 0.1 0.2 0.0 0.1 0.1 0.0 1.0 19.8 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.2 0.2 0.0 0.2 0.4 0.0 0.1 0.0 0.2 0.1 1.2 0.1 0.4 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.3 0.2 0.4 1.5 0.4 0.1 0.4 0.0 0.1 0.4 0.4 0.9 0.4 0.4 0.3 0.5 0.2 0.7 0.2 0.5 0.8 0.5 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.7 1.3 17.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.1 0.4 0.5 0.0 0.0 0.1 0.4 0.1 0.4 0.0 0.3 0.0 2.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.3 0.3 0.3 0.6 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.2 0.1 0.0 0.6 0.0 2.1 0.5 0.1 0.2 0.3 0.3 0.0 0.1 0.1 0.5 0.1 DAP ENSG00000112977 "Death associated protein" P51397 5 10679230-10761234 "Predicted intracellular proteins" "Apoptosis, Autophagy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 193.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA029456 Uncertain Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" "Vesicles, Mitochondria" Nucleoplasm "HPA029456: AB_10601262" "unprognostic (2.70e-2)" "unprognostic (3.48e-1)" "unprognostic (2.25e-1)" "unprognostic (1.88e-2)" "unprognostic (1.95e-1)" "unprognostic (1.12e-1)" "prognostic unfavorable (2.15e-5)" "unprognostic (4.05e-2)" "unprognostic (1.19e-1)" "unprognostic (1.52e-3)" "unprognostic (3.50e-1)" "unprognostic (1.91e-2)" "unprognostic (3.03e-3)" "unprognostic (2.11e-1)" "unprognostic (2.39e-1)" "unprognostic (8.58e-3)" "unprognostic (2.04e-2)" 54.5 103.7 34.8 47.0 33.6 44.5 69.0 30.6 38.8 75.1 91.0 65.8 93.8 59.0 68.6 39.0 63.1 83.3 60.9 35.4 32.9 99.0 161.8 64.9 45.6 39.9 37.1 75.0 241.4 82.9 80.9 64.1 33.1 76.7 69.1 13.8 129.4 92.2 9.4 46.9 87.0 63.6 34.7 46.3 106.3 27.3 36.6 41.2 92.9 14.7 50.8 87.9 49.0 32.5 107.3 76.3 92.6 86.3 169.6 203.6 102.8 255.3 394.4 189.5 217.8 54.7 88.9 46.3 163.8 318.4 119.6 20.6 58.3 151.7 205.1 245.3 42.5 62.2 137.9 136.0 159.7 117.7 44.6 105.4 51.9 124.5 223.3 109.1 358.4 51.1 73.5 152.5 188.2 85.0 63.1 74.9 33.7 143.9 172.9 86.0 40.9 76.8 250.1 195.2 62.7 84.3 261.2 105.2 69.6 70.6 83.4 170.4 177.4 116.8 125.9 78.1 137.6 85.1 118.6 68.3 115.4 225.3 179.3 40.7 78.0 45.0 32.7 70.7 38.5 39.8 33.6 29.0 76.8 25.9 24.4 24.4 63.4 33.1 72.1 62.3 39.3 62.2 34.8 33.6 30.6 38.8 35.4 32.9 39.9 37.1 33.1 34.7 36.6 32.5 29.0 16.0 44.7 8.5 36.7 19.2 62.6 14.1 19.9 8.9 90.4 39.2 12.3 72.9 27.3 53.3 6.2 66.2 42.3 75.6 133.1 97.3 13.3 45.0 31.7 38.4 44.3 23.4 5.5 193.0 98.5 45.1 61.7 58.1 35.0 68.9 41.0 109.1 52.3 5.0 7.8 115.3 10.2 49.9 34.2 33.4 29.8 56.5 28.4 35.6 44.2 29.8 32.0 22.6 6.2 124.8 69.0 34.3 74.8 78.6 133.5 100.5 15.1 8.1 0.0 18.6 41.8 30.7 7.1 15.7 18.2 101.0 24.1 43.0 70.4 108.8 DCAF15 "C19orf72, MGC99481" ENSG00000132017 "DDB1 and CUL4 associated factor 15" Q66K64 19 13952492-13961449 "Predicted intracellular proteins" "Immunity, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068351 Approved Vesicles,Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 12: NES - Nervous system development" "Cluster 7: Non-specific - Mitochondria" Mitochondria Vesicles "HPA068351: AB_2685977" "unprognostic (6.91e-2)" "unprognostic (6.55e-3)" "unprognostic (3.03e-2)" "unprognostic (5.18e-3)" "unprognostic (1.95e-1)" "unprognostic (1.89e-2)" "unprognostic (1.83e-3)" "unprognostic (9.72e-2)" "unprognostic (8.03e-2)" "unprognostic (1.21e-1)" "prognostic favorable (7.97e-4)" "unprognostic (1.98e-2)" "prognostic unfavorable (1.34e-5)" "unprognostic (7.97e-3)" "unprognostic (1.26e-1)" "unprognostic (1.07e-1)" "unprognostic (1.59e-1)" 17.6 10.7 5.9 10.3 6.0 20.5 18.1 7.1 7.9 18.7 4.7 18.1 6.9 17.0 4.3 24.0 16.7 4.5 18.6 6.0 5.6 16.2 13.9 18.6 13.5 5.6 5.2 15.5 13.7 7.1 16.5 7.3 5.2 17.0 5.2 3.6 16.1 5.3 22.9 30.2 23.4 5.1 4.9 33.4 14.0 44.7 5.6 14.6 17.0 8.6 10.8 15.6 21.6 5.4 18.9 11.5 29.5 16.2 3.1 4.5 13.5 12.7 8.8 26.1 25.9 20.4 7.9 17.3 14.4 12.3 15.4 16.7 18.9 12.0 9.2 21.0 33.8 21.3 21.0 21.4 6.5 17.8 30.2 5.9 10.9 19.3 8.6 9.4 13.1 27.4 22.9 24.8 11.6 28.7 32.0 33.0 35.2 12.7 17.8 29.2 10.4 11.8 14.1 14.3 18.8 19.3 11.4 8.1 10.7 12.1 10.5 22.7 9.2 17.8 13.1 28.3 24.1 17.4 20.7 18.3 11.4 25.8 15.6 0.2 0.3 0.9 0.3 0.3 0.2 0.3 0.2 0.3 0.2 0.4 0.1 0.3 0.6 0.1 0.2 0.4 0.6 0.2 5.9 6.0 7.1 7.9 6.0 5.6 5.6 5.2 5.2 4.9 5.6 5.4 19.5 0.0 0.0 6.8 19.7 4.8 10.5 6.9 8.6 17.3 8.9 10.7 2.9 10.0 3.8 9.2 8.4 13.7 24.4 9.6 1.9 11.0 5.0 7.0 7.8 10.9 7.7 9.4 5.2 10.3 15.1 7.5 13.7 7.0 1.3 15.0 7.1 3.4 15.7 15.2 3.4 5.7 4.1 8.1 7.0 9.5 18.3 14.3 1.8 8.4 13.8 9.2 16.5 7.1 5.5 9.9 9.6 12.0 18.3 6.4 4.5 4.7 3.9 13.9 6.6 6.0 7.9 35.6 19.9 10.0 9.8 13.8 21.2 10.4 7.9 8.9 DCAF5 "BCRG2, BCRP2, D14S1461E, KIAA1824, WDR22" ENSG00000139990 "DDB1 and CUL4 associated factor 5" Q96JK2 14 69050881-69153150 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 149.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041575, HPA048098" Uncertain Approved Mitochondria NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 34: Spermatids - Unknown function" Mitochondria "HPA041575: AB_2677558, HPA048098: AB_2680263" "unprognostic (8.12e-2)" "unprognostic (3.28e-2)" "unprognostic (4.26e-3)" "unprognostic (3.30e-1)" "unprognostic (1.58e-1)" "unprognostic (3.44e-1)" "unprognostic (2.27e-2)" "unprognostic (3.13e-2)" "unprognostic (1.25e-1)" "unprognostic (2.43e-1)" "unprognostic (5.80e-2)" "unprognostic (1.02e-1)" "unprognostic (1.63e-2)" "unprognostic (2.80e-2)" "unprognostic (1.02e-1)" "unprognostic (1.30e-1)" "unprognostic (2.06e-1)" 30.0 22.5 16.1 23.4 15.9 30.2 27.2 16.4 16.5 29.3 17.0 34.0 21.6 28.3 22.3 30.9 28.8 24.4 31.3 16.5 16.6 24.6 31.4 31.0 27.6 15.8 15.0 28.5 22.0 36.4 28.8 25.4 16.0 29.8 21.2 20.8 27.2 25.1 74.3 30.5 25.9 32.7 14.1 27.7 26.2 60.5 17.2 39.4 30.1 51.7 25.6 29.2 28.3 14.5 48.3 15.0 34.7 32.5 37.7 32.9 22.7 22.2 32.1 24.9 31.2 19.4 29.9 26.4 19.9 34.7 18.8 23.0 24.7 33.2 23.2 36.0 13.7 28.4 15.8 14.0 28.6 10.9 33.2 37.3 34.0 22.3 31.1 43.0 37.7 31.1 22.4 21.6 25.1 28.6 34.7 19.0 15.6 22.6 23.7 22.8 32.9 10.6 33.1 37.0 24.7 27.8 29.7 30.7 19.4 29.7 37.5 22.0 34.4 42.2 39.4 19.6 13.2 28.4 9.9 23.9 28.1 13.0 13.0 21.1 4.3 16.4 31.0 4.0 26.3 8.2 16.7 23.0 5.7 8.6 15.7 19.7 5.4 32.3 3.0 6.0 8.2 13.1 16.1 15.9 16.4 16.5 16.5 16.6 15.8 15.0 16.0 14.1 17.2 14.5 28.8 44.8 57.8 71.8 24.9 26.3 19.1 21.4 38.1 18.5 23.3 19.0 58.8 32.9 39.4 14.7 27.1 19.4 43.6 20.9 1.9 25.1 149.9 28.7 30.6 32.1 23.4 25.6 88.8 24.9 19.3 27.2 32.1 31.9 37.2 28.0 26.0 33.2 19.6 18.5 85.6 22.0 22.4 19.7 23.7 89.3 31.1 24.3 10.6 74.9 21.8 22.3 52.5 76.9 61.6 29.2 16.0 34.3 35.8 19.9 20.9 14.0 41.2 24.9 46.0 29.1 26.6 75.2 19.8 37.9 19.9 15.3 38.0 31.2 21.3 23.5 DDT "D-DT, DDCT, MIF-2, MIF2" ENSG00000099977 "D-dopachrome tautomerase" P30046 22 23971365-23979828 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Melanin biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 835.9" "Cell type enhanced" "Detected in all" "Hepatocytes: 4869.6;Proximal tubular cells: 1415.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEK 293: 262.9" "HPA049871, HPA074115" Approved Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 2: Hepatocytes - Metabolism" Mitochondria "HPA049871: AB_2680926, HPA074115: " "unprognostic (1.77e-2)" "unprognostic (1.13e-1)" "unprognostic (1.40e-1)" "unprognostic (1.22e-2)" "unprognostic (8.09e-2)" "unprognostic (4.00e-3)" "unprognostic (2.02e-3)" "unprognostic (6.58e-2)" "unprognostic (4.66e-2)" "unprognostic (2.23e-2)" "unprognostic (1.96e-1)" "unprognostic (6.06e-3)" "unprognostic (1.12e-1)" "unprognostic (7.34e-2)" "unprognostic (3.30e-1)" "unprognostic (3.81e-1)" "unprognostic (2.61e-3)" 125.7 126.7 29.6 15.1 30.6 39.6 99.0 33.1 38.0 69.6 28.7 128.5 44.2 62.6 16.2 119.1 67.3 6.3 167.0 28.9 32.2 218.2 835.9 69.2 13.7 30.7 29.6 83.0 260.9 24.3 47.7 10.7 30.7 109.0 24.2 12.8 82.7 15.7 129.3 89.8 120.7 8.6 30.7 66.3 176.2 39.2 32.9 12.3 80.1 15.7 11.9 86.8 76.4 33.9 107.6 44.8 15.4 34.9 29.0 24.9 92.6 30.4 20.7 26.1 27.1 39.8 30.6 101.9 27.8 16.1 37.7 86.3 38.3 38.1 17.1 43.6 262.9 60.8 58.9 88.3 28.9 136.2 58.8 25.5 28.5 26.3 23.1 27.9 28.7 16.0 56.8 40.2 26.9 53.0 30.1 123.1 46.2 94.4 134.2 65.3 27.0 148.9 46.4 39.2 51.7 49.2 62.8 117.7 95.9 20.6 30.8 42.3 33.1 26.8 59.9 27.8 32.2 122.6 43.9 65.1 53.1 49.7 52.5 63.5 92.9 72.4 46.0 82.8 47.5 75.3 55.3 49.1 87.8 70.7 49.2 48.9 58.3 61.6 79.1 130.4 74.5 78.8 29.6 30.6 33.1 38.0 28.9 32.2 30.7 29.6 30.7 30.7 32.9 33.9 116.9 83.3 86.3 11.1 178.3 138.9 220.5 278.8 176.4 58.4 266.6 379.7 21.3 499.0 153.2 242.8 89.6 202.6 134.1 533.1 718.1 237.2 202.1 150.8 126.4 103.4 259.6 230.2 9.1 375.7 288.2 103.9 163.1 260.3 129.4 97.1 154.9 4869.6 281.0 43.7 11.0 402.8 187.2 240.4 162.2 411.0 117.1 172.2 158.3 9.4 235.8 119.6 135.9 6.0 18.8 233.6 395.1 110.6 166.1 257.5 935.1 1415.8 97.6 100.0 78.9 109.5 127.6 117.9 43.8 280.6 188.0 299.8 140.3 212.5 558.7 291.3 DDX49 "Dbp8, FLJ10432" ENSG00000105671 "DEAD-box helicase 49" Q9Y6V7 19 18919705-18929189 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 103.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041870, HPA048093" Enhanced Approved Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA041870: AB_2677717, HPA048093: AB_2680262" "unprognostic (3.51e-1)" "prognostic favorable (2.01e-6)" "unprognostic (2.28e-2)" "unprognostic (1.28e-1)" "unprognostic (8.56e-2)" "unprognostic (1.60e-2)" "prognostic unfavorable (7.05e-4)" "unprognostic (4.12e-2)" "unprognostic (2.41e-3)" "unprognostic (8.67e-2)" "unprognostic (6.46e-3)" "unprognostic (5.13e-2)" "prognostic unfavorable (7.44e-5)" "unprognostic (3.93e-2)" "unprognostic (2.99e-2)" "unprognostic (4.97e-2)" "unprognostic (3.24e-1)" 16.5 17.7 17.1 13.9 17.3 23.3 15.5 17.9 22.1 16.0 14.0 17.4 15.7 15.9 5.9 25.9 13.9 7.9 18.2 18.2 16.5 15.6 24.9 13.7 16.1 17.1 16.0 14.6 20.1 12.6 11.3 13.4 16.7 16.4 7.4 4.8 18.0 10.8 33.6 27.1 14.8 9.9 17.7 16.1 15.7 19.2 17.3 14.1 13.6 13.6 10.3 17.5 17.5 19.3 46.5 47.4 19.0 61.3 28.1 21.1 71.0 29.2 19.8 50.9 40.1 54.6 45.8 60.6 86.7 29.1 16.1 39.4 42.9 39.8 14.8 18.9 110.5 29.9 49.9 48.6 63.5 77.5 40.1 44.4 35.9 40.7 41.9 14.4 23.3 46.9 58.2 43.1 18.2 104.4 56.6 37.9 62.7 50.3 112.8 62.8 31.5 65.9 27.4 28.2 67.2 69.7 38.2 36.6 48.2 9.8 39.2 37.6 29.5 24.3 27.9 92.0 48.7 55.5 73.0 57.1 31.1 88.8 39.3 17.1 21.9 16.7 14.8 26.2 12.0 9.1 11.0 11.1 31.1 9.8 10.9 12.1 8.6 19.5 18.1 13.7 18.0 12.7 17.1 17.3 17.9 22.1 18.2 16.5 17.1 16.0 16.7 17.7 17.3 19.3 15.6 3.2 10.0 4.9 20.5 22.6 18.7 28.0 14.8 19.5 25.2 29.1 13.8 27.1 20.5 18.4 4.2 46.5 27.0 48.0 37.2 35.0 37.2 18.8 26.5 15.3 25.8 18.3 7.4 52.2 50.3 19.0 19.4 24.7 18.4 25.1 7.5 14.8 33.5 10.1 7.6 31.5 30.5 21.0 22.0 103.0 21.5 18.8 26.6 4.7 28.5 18.3 29.9 6.0 8.2 29.8 30.7 19.9 29.5 21.5 48.0 25.0 12.5 24.1 19.7 21.1 26.9 33.4 31.8 29.5 28.3 42.1 20.8 38.1 39.4 21.5 DEPTOR "DEP.6, DEPDC6, FLJ12428" ENSG00000155792 "DEP domain containing MTOR interacting protein" Q8TB45 8 119873717-120050918 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 158.2;tongue: 122.3" "Cell type enhanced" "Detected in many" "Distal tubular cells: 86.1;Glandular and luminal cells: 66.1;Oligodendrocytes: 123.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 11 "myeloid DC: 20.3" "Lineage enriched" "Detected in many" 11 "dendritic cells: 20.3" "Cell line enhanced" "Detected in many" "Daudi: 105.1;RPMI-8226: 193.2;RPTEC TERT1: 149.3;U-698: 55.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020841, HPA023938, HPA023945, HPA024011" Enhanced Approved "Nucleoplasm,Nuclear bodies,Mitochondria" No No "Cluster 28: Myeloid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 25: RPMI-8226 - Immune response" "Cluster 44: Endometrium - Transcription" Mitochondria "Nucleoplasm, Nuclear bodies" "CAB020841: , HPA023938: AB_1847606, HPA023945: AB_1847607, HPA024011: AB_1847608" "unprognostic (3.41e-1)" "unprognostic (1.95e-1)" "unprognostic (1.53e-2)" "unprognostic (1.15e-2)" "unprognostic (3.19e-1)" "unprognostic (2.57e-1)" "unprognostic (1.08e-1)" "unprognostic (4.13e-3)" "unprognostic (2.43e-1)" "unprognostic (2.49e-2)" "unprognostic (3.24e-2)" "unprognostic (6.02e-2)" "unprognostic (7.29e-2)" "unprognostic (5.66e-2)" "unprognostic (1.02e-1)" "unprognostic (4.16e-2)" "unprognostic (2.84e-2)" 14.4 52.8 12.0 3.0 16.7 2.0 20.7 12.6 11.9 39.2 3.8 23.3 16.9 16.5 11.1 15.2 27.1 10.8 5.1 9.7 23.2 40.0 16.3 5.3 10.1 15.8 12.5 24.7 11.9 16.9 11.4 4.9 15.3 12.1 9.9 2.0 106.3 15.6 158.2 6.6 14.5 15.5 14.8 9.5 40.0 2.9 16.3 5.1 98.0 122.3 2.9 5.6 7.0 24.2 0.1 3.5 0.3 1.1 21.0 6.2 0.3 0.1 0.3 0.6 0.5 2.4 0.4 105.1 2.3 1.2 0.3 0.3 5.4 0.2 0.4 2.3 2.7 14.2 0.9 0.6 12.8 3.0 23.7 5.5 9.5 0.8 0.6 0.1 0.0 1.8 0.1 16.9 0.3 7.1 0.1 2.5 1.3 45.5 3.7 0.4 4.9 193.2 149.3 4.1 3.2 0.7 1.7 11.0 3.2 2.8 9.6 0.5 0.0 0.4 0.9 21.4 0.5 45.4 11.4 55.2 6.5 3.9 0.6 0.0 0.9 0.0 0.2 1.7 0.8 0.1 0.4 0.7 20.3 0.1 0.8 0.6 0.3 0.4 0.2 1.0 0.4 1.0 12.0 16.7 12.6 11.9 9.7 23.2 15.8 12.5 15.3 14.8 16.3 24.2 23.1 6.4 9.3 4.9 2.9 5.2 15.4 3.8 27.3 2.1 16.5 10.4 2.4 15.7 8.4 25.8 0.0 0.6 0.8 2.7 86.1 5.7 2.2 19.0 9.7 7.5 16.7 12.4 14.5 11.8 4.1 10.0 29.6 66.1 12.0 5.4 2.5 12.7 3.3 0.0 31.0 7.7 0.0 16.0 39.5 2.2 11.8 14.9 14.2 46.9 1.5 1.2 2.1 9.5 123.9 1.1 36.5 3.4 6.4 7.1 21.0 33.6 1.1 0.7 0.0 8.1 5.7 3.6 3.8 16.5 5.5 0.4 1.3 6.0 16.5 21.9 DGKA "DAGK, DAGK1, DGK-alpha" ENSG00000065357 "Diacylglycerol kinase alpha" P23743 12 55927319-55954027 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 101.5;lymphoid tissue: 198.1" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 49.0;Squamous epithelial cells: 40.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Lineage enriched" "Detected in all" 4 "T-cells: 86.9" "Cell line enhanced" "Detected in many" "HBEC3-KT: 130.4;hTERT-HME1: 133.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041645, HPA045462" Approved Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 58: T-cells - T-cell receptor" Vesicles "Nucleoplasm, Mitochondria" "HPA041645: AB_2677595, HPA045462: AB_2679335" "unprognostic (1.12e-3)" "unprognostic (1.43e-2)" "unprognostic (1.62e-2)" "unprognostic (2.63e-2)" "unprognostic (5.23e-2)" "unprognostic (2.04e-1)" "unprognostic (3.62e-1)" "unprognostic (3.31e-2)" "unprognostic (5.28e-2)" "unprognostic (1.94e-1)" "unprognostic (1.82e-2)" "unprognostic (2.46e-1)" "prognostic unfavorable (1.66e-5)" "unprognostic (4.06e-1)" "unprognostic (1.00e-1)" "unprognostic (1.47e-1)" "unprognostic (7.02e-2)" 12.7 12.8 7.6 50.0 9.8 31.9 11.0 6.6 9.2 22.9 7.0 25.6 51.2 13.1 9.9 101.5 11.4 15.8 8.5 7.2 5.2 7.9 3.7 18.6 95.5 5.2 5.0 10.9 14.6 12.0 6.9 14.9 5.3 24.8 26.9 2.8 35.5 9.6 2.3 84.7 64.8 14.1 4.8 53.8 12.4 12.3 5.0 198.1 10.5 4.2 101.8 28.4 39.0 6.8 22.2 13.2 9.3 12.4 22.4 29.0 2.8 47.2 47.8 18.2 13.5 6.9 35.2 13.5 11.1 31.5 6.2 38.7 10.3 130.4 21.4 14.4 2.5 21.1 26.8 3.6 19.1 6.7 20.9 25.1 68.4 25.2 133.9 60.6 37.9 78.8 2.4 18.7 49.4 2.3 54.3 8.6 2.0 18.1 15.5 23.8 2.9 2.0 43.7 60.9 1.6 5.6 15.5 0.9 1.7 23.8 9.3 6.4 34.0 12.0 8.4 2.8 1.7 2.9 1.2 32.4 13.8 17.5 3.4 17.0 7.4 15.3 18.5 5.2 35.5 20.4 70.6 33.0 10.5 16.2 86.9 51.5 13.3 14.1 3.5 10.5 86.7 36.2 7.6 9.8 6.6 9.2 7.2 5.2 5.2 5.0 5.3 4.8 5.0 6.8 4.5 3.2 6.5 1.6 25.7 15.0 9.7 21.1 26.7 1.2 4.0 4.6 2.9 4.3 19.1 5.5 0.0 16.3 12.2 35.4 0.0 5.1 9.4 1.9 6.5 5.3 2.4 11.2 11.2 9.4 4.3 8.2 15.3 3.0 7.0 2.4 4.2 0.2 4.2 0.0 5.2 7.7 2.0 6.9 21.6 7.0 3.7 14.0 0.0 5.6 15.7 2.6 10.3 9.0 0.8 25.3 14.4 3.0 14.8 8.2 49.0 0.3 5.2 0.5 6.6 1.5 4.2 6.6 4.2 40.4 13.9 26.4 37.4 1.6 9.7 20.1 DHFR ENSG00000228716 "Dihydrofolate reductase" P00374 5 80626226-80654983 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Methotrexate resistance, One-carbon metabolism" "Oxidoreductase, RNA-binding" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 145.8;Spermatocytes: 132.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037129, HPA051465" Uncertain Approved Mitochondria NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Mitochondria "CAB037129: AB_439683, HPA051465: AB_2681494" "unprognostic (1.44e-2)" "unprognostic (1.03e-2)" "unprognostic (2.24e-3)" "unprognostic (2.91e-3)" "unprognostic (3.27e-1)" "unprognostic (1.32e-1)" "unprognostic (2.83e-2)" "unprognostic (2.35e-2)" "unprognostic (2.02e-2)" "unprognostic (4.19e-3)" "unprognostic (1.83e-2)" "unprognostic (2.55e-1)" "unprognostic (1.15e-2)" "unprognostic (1.82e-2)" "unprognostic (2.49e-1)" "unprognostic (1.57e-1)" "unprognostic (1.09e-1)" 25.2 5.3 15.3 20.7 16.5 54.3 12.0 15.8 21.9 8.0 13.3 21.4 24.5 8.6 7.0 14.1 7.4 8.5 7.2 13.8 15.5 21.3 60.1 7.5 41.5 16.6 16.6 6.6 3.2 9.1 6.3 14.4 16.6 8.9 25.3 10.3 6.8 9.5 19.6 9.8 25.1 12.0 16.5 10.3 12.2 18.5 15.8 60.7 8.2 25.8 39.5 10.3 5.7 17.7 98.1 66.6 164.8 122.7 30.7 32.0 60.6 76.5 58.1 130.2 149.0 63.8 114.6 196.9 32.5 44.6 106.0 67.0 214.4 98.6 208.5 88.2 132.1 94.8 104.5 59.5 6.6 111.7 40.3 22.3 9.9 116.9 13.0 22.2 63.9 142.0 108.3 146.7 133.5 98.2 276.5 44.9 83.6 48.3 38.5 176.7 323.3 194.1 75.1 61.5 134.3 93.7 107.9 49.9 54.6 83.5 98.5 108.6 38.5 41.0 62.0 116.0 148.3 68.2 146.6 210.3 91.5 222.1 107.7 0.2 0.3 0.2 0.5 0.6 0.2 0.5 0.6 0.8 0.5 0.5 0.5 0.6 0.8 0.5 0.5 0.8 0.9 0.6 15.3 16.5 15.8 21.9 13.8 15.5 16.6 16.6 16.6 16.5 15.8 17.7 4.1 6.4 11.7 4.9 21.4 6.9 6.5 6.0 4.0 3.5 8.9 8.9 13.0 4.3 6.1 14.7 2.1 35.2 7.4 19.3 9.8 7.4 7.4 10.8 7.7 7.7 4.9 145.8 7.3 3.7 47.3 12.0 11.7 8.0 2.5 22.0 10.0 48.3 44.7 3.3 7.2 19.1 4.1 18.9 4.4 6.4 14.0 12.8 0.0 4.7 7.1 14.5 13.4 3.5 6.0 4.7 10.3 16.1 60.9 2.9 26.6 40.0 6.9 3.2 13.1 9.0 12.5 132.2 49.8 21.2 5.5 13.3 11.8 12.3 38.1 12.1 DHFR2 "DHFRL1, DHFRP4, FLJ16119" ENSG00000178700 "Dihydrofolate reductase 2" Q86XF0 3 94047836-94063389 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "One-carbon metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 12.8;Ductal cells: 6.3;Respiratory ciliated cells: 8.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 13 "hTERT-RPE1: 154.6" HPA051465 Uncertain Approved Mitochondria NA NA "Cluster 32: T-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA051465: AB_2681494" "unprognostic (1.16e-1)" "unprognostic (1.15e-1)" "unprognostic (1.10e-2)" "unprognostic (3.50e-2)" "unprognostic (2.07e-1)" "unprognostic (1.38e-1)" "unprognostic (5.92e-2)" "unprognostic (1.33e-1)" "unprognostic (1.12e-1)" "unprognostic (4.62e-2)" "unprognostic (2.95e-1)" "unprognostic (1.52e-1)" "prognostic favorable (2.30e-6)" "unprognostic (1.63e-1)" "unprognostic (1.79e-1)" "unprognostic (1.13e-1)" "unprognostic (2.96e-2)" 3.3 4.9 3.9 3.8 5.2 1.8 5.3 6.0 5.2 5.2 4.8 4.2 4.1 7.9 6.4 3.5 6.3 5.1 3.7 4.1 4.1 5.9 6.7 4.5 5.7 4.8 4.2 10.1 5.3 6.5 2.5 3.2 5.0 6.4 4.6 3.2 4.4 4.9 1.4 4.2 4.9 5.4 4.2 4.9 4.7 4.7 4.4 5.7 6.7 2.1 4.6 3.3 2.4 6.5 3.8 6.5 4.2 4.4 5.7 7.2 1.7 5.7 6.0 2.8 3.2 1.4 5.7 2.5 3.8 3.0 3.7 5.0 3.3 3.9 4.4 8.5 1.8 3.1 2.9 3.4 6.0 2.2 3.6 7.6 5.1 3.3 4.2 154.6 2.9 11.9 1.6 5.6 3.7 4.5 10.8 1.2 3.7 10.8 6.7 2.7 5.7 4.1 4.1 1.9 5.4 5.3 8.3 2.2 9.6 3.3 5.6 3.1 4.8 4.4 7.4 1.8 2.2 4.1 4.4 3.5 4.4 5.5 6.2 2.2 1.1 2.0 1.8 1.7 3.3 1.8 2.4 2.9 0.7 2.2 3.2 3.0 1.7 1.4 1.8 2.1 3.2 1.3 3.9 5.2 6.0 5.2 4.1 4.1 4.8 4.2 5.0 4.2 4.4 6.5 2.8 12.8 5.8 0.0 0.9 0.0 0.0 0.0 0.0 0.0 3.6 3.4 0.0 0.0 1.8 3.7 0.0 2.4 2.3 0.0 3.9 6.3 0.0 3.5 4.4 2.5 0.0 0.0 0.0 5.5 1.7 2.5 0.0 2.9 2.5 4.9 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 2.6 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.4 0.0 0.0 5.6 8.7 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.8 1.3 3.5 0.0 0.0 DHRS3 "RDH17, retSDR1, Rsdr1, SDR1, SDR16C1" ENSG00000162496 "Dehydrogenase/reductase 3" O75911 1 12567910-12618210 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 323.7" "Cell type enhanced" "Detected in many" "Late spermatids: 409.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "gdT-cell: 86.8;MAIT T-cell: 63.1;memory CD4 T-cell: 46.9;memory CD8 T-cell: 41.0;myeloid DC: 24.0;naive CD4 T-cell: 79.2;naive CD8 T-cell: 50.1;NK-cell: 41.1" "Group enriched" "Detected in many" 5 "dendritic cells: 24.0;NK-cells: 41.1;T-cells: 86.8" "Cell line enhanced" "Detected in many" "A549: 107.4;CAPAN-2: 206.9;hTERT-RPE1: 196.7;SK-BR-3: 104.6;WM-115: 192.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010844 Supported Approved Nucleoli,Mitochondria NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 85: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoli, Mitochondria" "HPA010844: AB_1847653" "unprognostic (7.83e-2)" "unprognostic (2.11e-1)" "unprognostic (1.82e-2)" "unprognostic (1.74e-3)" "unprognostic (1.87e-1)" "unprognostic (3.68e-2)" "unprognostic (2.25e-3)" "unprognostic (5.06e-2)" "unprognostic (3.40e-2)" "unprognostic (5.18e-2)" "unprognostic (1.29e-2)" "unprognostic (1.92e-1)" "unprognostic (1.80e-1)" "unprognostic (1.02e-1)" "unprognostic (1.76e-1)" "prognostic favorable (2.65e-4)" "unprognostic (5.48e-2)" 150.9 21.6 38.3 18.6 37.8 13.8 115.8 34.8 41.1 89.8 96.3 60.8 50.2 34.6 25.3 117.1 53.9 33.5 73.2 38.0 38.0 87.8 323.7 56.4 18.0 57.2 37.8 38.8 108.4 31.3 48.8 19.6 40.1 169.6 21.2 8.6 67.0 48.2 76.2 71.9 52.5 16.8 40.6 27.0 87.1 20.2 41.3 10.4 121.2 24.7 8.9 73.0 107.0 44.2 18.1 107.4 0.1 42.7 54.9 5.0 11.9 6.2 0.3 0.2 0.4 11.8 206.9 0.1 5.2 57.7 17.6 79.9 21.4 10.6 0.2 0.1 36.3 16.5 11.3 57.3 8.5 0.3 0.3 27.9 13.5 0.3 0.5 196.7 18.0 0.7 24.3 0.3 0.3 3.0 4.4 1.0 6.8 18.5 40.3 0.5 0.1 20.2 0.1 36.6 1.3 2.0 35.0 104.6 6.6 13.2 10.3 4.8 13.5 0.5 2.2 30.3 0.4 3.3 0.2 0.2 23.9 1.4 192.8 9.2 0.8 0.1 86.8 0.5 63.1 0.6 46.9 41.0 24.0 0.7 79.2 50.1 4.7 41.1 1.1 3.0 1.4 48.2 38.3 37.8 34.8 41.1 38.0 38.0 57.2 37.8 40.1 40.6 41.3 44.2 139.5 96.1 55.9 26.8 3.4 25.6 136.0 114.8 59.2 2.0 17.5 22.6 42.3 45.8 93.4 20.2 18.8 34.4 35.5 83.8 23.5 99.3 99.6 69.8 50.2 54.1 25.1 23.6 3.7 163.1 45.0 56.4 32.1 83.7 15.8 2.6 73.5 181.3 67.1 0.0 3.3 33.0 42.7 69.6 8.4 409.5 22.7 43.6 7.2 17.8 11.5 15.3 38.1 1.0 0.6 129.6 69.5 9.8 3.5 76.2 112.6 52.9 82.8 2.4 0.0 10.5 30.8 1.9 1.4 51.7 27.0 26.3 28.3 7.9 33.0 156.8 DHRS7 "retDSR4, SDR34C1" ENSG00000100612 "Dehydrogenase/reductase 7" Q9Y394 14 60144119-60169856 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 615.8" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 840.4" "Cancer enriched" "Detected in all" 5 "prostate cancer: 199.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031121, HPA078401" Enhanced Approved Nucleoplasm,Mitochondria No No "Cluster 5: Granulocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Mitochondria" "HPA031121: AB_10600803, HPA078401: " "prognostic favorable (6.42e-4)" "unprognostic (5.20e-2)" "unprognostic (6.70e-3)" "unprognostic (1.67e-1)" "unprognostic (2.69e-1)" "prognostic unfavorable (2.51e-4)" "unprognostic (4.65e-2)" "unprognostic (4.31e-2)" "unprognostic (2.62e-1)" "prognostic unfavorable (7.99e-4)" "unprognostic (1.73e-1)" "unprognostic (1.59e-1)" "prognostic favorable (1.92e-10)" "unprognostic (8.35e-3)" "unprognostic (1.48e-1)" "unprognostic (1.07e-1)" "unprognostic (3.61e-1)" 62.1 103.4 50.8 43.8 53.9 61.0 58.5 59.2 75.4 48.9 50.2 73.0 108.9 49.8 96.5 44.3 45.9 59.1 47.1 49.9 55.1 100.5 146.4 64.2 45.5 62.3 54.9 64.9 76.8 226.8 54.7 29.6 63.3 409.9 69.5 111.1 317.5 134.6 615.8 46.6 181.0 51.0 57.8 45.4 182.3 9.8 52.0 39.2 120.3 136.0 49.4 51.7 41.1 65.6 221.3 52.9 41.8 89.3 219.6 74.4 42.8 74.3 186.4 26.5 59.0 37.3 149.8 21.5 41.7 76.8 78.0 92.7 57.2 108.3 34.5 156.1 36.0 53.7 28.7 60.9 110.1 71.8 1.7 63.3 116.7 47.6 153.0 50.8 52.5 66.2 18.2 52.6 61.4 59.2 40.9 67.2 18.6 151.2 55.4 42.7 50.8 24.4 118.3 70.5 83.4 99.8 72.6 118.0 168.2 52.7 72.7 32.5 35.8 126.6 38.7 36.9 44.2 18.3 7.9 45.0 62.6 64.8 93.5 743.5 213.1 519.6 335.7 159.1 340.6 184.4 238.9 298.5 185.0 167.0 134.6 258.5 835.4 294.7 224.0 388.8 215.5 450.2 50.8 53.9 59.2 75.4 49.9 55.1 62.3 54.9 63.3 57.8 52.0 65.6 109.6 54.5 102.5 16.0 72.2 34.0 70.3 233.2 52.3 25.7 81.2 57.4 27.6 160.2 138.4 86.5 83.4 29.6 210.4 101.3 19.6 222.5 2.1 56.2 55.5 89.7 46.5 20.4 12.2 165.9 88.7 87.9 120.8 120.0 178.5 22.9 48.5 166.4 94.4 42.1 19.0 102.2 386.6 54.5 70.6 3.5 82.3 98.7 108.5 16.9 172.5 94.4 299.7 26.2 20.1 210.6 114.5 84.2 99.0 263.4 840.4 44.1 57.0 70.7 85.5 66.4 73.7 1.6 2.9 47.0 25.4 20.8 152.1 19.7 79.2 47.1 DLD "DLDH, E3, GCSL, LAD, OGDC-E3" ENSG00000091140 "Dihydrolipoamide dehydrogenase" P09622 7 107891162-107931730 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 357.0" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 356.2;Distal tubular cells: 226.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044849 Supported Approved Nucleoplasm,Mitochondria NA NA 10000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoplasm "HPA044849: AB_2679111" "unprognostic (2.01e-3)" "unprognostic (2.26e-1)" "unprognostic (1.27e-2)" "unprognostic (9.27e-2)" "unprognostic (5.01e-3)" "unprognostic (9.27e-2)" "unprognostic (2.48e-1)" "unprognostic (2.83e-2)" "unprognostic (1.19e-1)" "unprognostic (3.95e-2)" "unprognostic (9.43e-2)" "unprognostic (7.35e-2)" "prognostic favorable (7.58e-9)" "unprognostic (4.08e-2)" "unprognostic (1.88e-1)" "unprognostic (4.45e-3)" "unprognostic (1.18e-1)" 108.7 98.9 22.7 42.1 23.7 54.0 49.0 27.1 29.1 36.3 35.6 109.0 81.8 45.3 21.2 94.1 34.3 48.5 264.1 23.1 29.5 153.3 112.8 39.3 50.1 27.1 27.4 30.0 49.2 136.7 27.8 43.1 26.6 45.7 99.3 35.0 50.2 50.3 295.0 38.9 71.9 67.7 24.9 38.4 80.5 31.3 25.7 43.2 64.2 357.0 67.5 66.1 32.7 23.4 171.4 134.5 74.8 127.9 104.6 91.4 88.4 96.5 80.8 110.6 86.2 159.5 95.5 165.9 159.6 103.0 177.7 110.9 150.2 135.8 166.1 111.1 88.4 116.9 175.6 116.7 80.3 194.7 116.0 104.8 97.6 116.4 63.4 72.3 134.0 137.0 298.5 119.7 121.8 188.1 161.8 138.9 87.4 206.0 98.2 113.1 117.8 225.9 151.8 250.8 92.3 99.9 156.3 262.1 143.9 149.9 100.5 165.8 87.9 120.7 97.3 238.1 149.4 89.3 187.1 114.6 115.0 204.1 130.2 132.7 63.9 136.0 46.9 81.6 49.4 37.8 46.8 46.8 87.2 38.5 47.9 50.5 39.9 68.1 116.9 29.9 49.0 64.2 22.7 23.7 27.1 29.1 23.1 29.5 27.1 27.4 26.6 24.9 25.7 23.4 26.7 28.9 20.7 14.7 26.3 31.4 42.7 124.7 31.3 47.1 24.0 19.2 356.2 51.5 70.5 79.1 22.9 110.2 27.3 56.1 226.9 69.3 10.2 27.6 26.2 32.2 30.6 53.9 23.9 55.9 62.7 36.3 36.7 28.0 26.6 35.3 26.0 86.8 69.2 21.9 25.3 44.1 114.0 41.0 26.5 7.3 23.3 37.5 37.4 15.9 62.2 36.0 38.1 21.1 16.7 42.6 51.4 42.2 30.7 24.3 60.0 178.9 55.5 45.5 26.3 28.4 44.8 55.2 51.5 48.0 32.4 108.4 29.5 73.7 78.7 39.2 DMAC2 "ATP5SL, FLJ10241" ENSG00000105341 "Distal membrane arm assembly complex 2" Q9NW81 19 41431318-41440717 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 47.9;Distal tubular cells: 39.2;Ductal cells: 44.0;Exocrine glandular cells: 40.5;Extravillous trophoblasts: 67.9;Hofbauer cells: 40.4;Proximal tubular cells: 46.3;Syncytiotrophoblasts: 46.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041427 Approved Approved Mitochondria NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA041427: AB_2677473" "unprognostic (1.42e-3)" "unprognostic (1.12e-1)" "unprognostic (3.17e-2)" "unprognostic (1.20e-1)" "unprognostic (6.88e-3)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.77e-4)" "unprognostic (4.37e-1)" "unprognostic (3.83e-2)" "unprognostic (1.18e-2)" "unprognostic (1.52e-2)" "unprognostic (2.10e-1)" "prognostic favorable (4.07e-5)" "unprognostic (5.20e-2)" "unprognostic (2.48e-1)" "unprognostic (6.60e-2)" "unprognostic (7.29e-3)" 27.3 33.2 29.3 16.1 29.5 18.2 26.2 30.6 34.7 27.6 26.1 41.1 44.9 31.5 10.4 34.5 27.0 14.1 110.1 29.5 30.7 40.8 36.2 32.6 20.5 31.4 31.4 24.4 35.9 33.2 16.2 18.8 31.0 27.5 17.9 18.7 26.4 20.2 68.4 30.8 42.6 22.3 29.8 26.7 38.2 13.9 31.7 25.7 26.9 80.1 17.2 37.1 26.2 30.5 39.1 134.9 48.4 32.4 33.2 32.9 28.8 31.9 36.9 55.7 49.5 96.7 43.5 40.4 47.8 47.3 30.1 28.6 36.9 59.0 28.4 37.3 47.4 38.1 35.2 70.8 49.5 64.6 36.8 52.5 53.3 44.6 31.3 37.9 66.2 54.7 52.3 39.2 38.0 48.4 59.2 26.4 60.5 55.7 40.3 48.7 38.1 35.8 53.8 53.4 34.6 57.1 51.4 41.9 35.0 38.4 39.2 72.3 50.0 47.7 52.0 29.3 55.7 41.0 41.7 36.6 42.5 46.5 35.0 15.0 28.4 24.2 22.0 25.7 22.9 16.8 16.7 22.2 40.3 19.7 17.7 17.2 9.3 22.9 22.8 26.6 21.0 23.2 29.3 29.5 30.6 34.7 29.5 30.7 31.4 31.4 31.0 29.8 31.7 30.5 25.4 28.9 16.9 0.0 3.1 0.0 0.0 0.0 0.0 0.0 25.7 19.7 0.0 0.0 5.6 12.9 0.0 47.9 9.6 0.0 39.2 44.0 0.0 10.3 17.3 11.6 0.0 0.0 0.0 40.5 67.9 9.3 0.0 14.7 7.6 22.4 0.0 0.0 40.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 31.6 0.0 0.0 0.0 0.0 29.2 0.0 0.0 1.4 0.0 0.0 46.3 2.9 0.0 0.0 0.0 12.3 0.0 0.0 0.0 0.0 46.4 6.5 21.0 0.0 0.0 DMAC2L "ATP5S, ATPW, HSU79253" ENSG00000125375 "Distal membrane arm assembly complex 2 like" Q99766 14 50312324-50335558 "Predicted intracellular proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 60.5;Cytotrophoblasts: 36.6;Extravillous trophoblasts: 24.6;Hofbauer cells: 28.5;Syncytiotrophoblasts: 41.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062690 Approved Nucleoplasm,Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Mitochondria" "HPA062690: AB_2684836" "unprognostic (2.24e-2)" "unprognostic (3.44e-3)" "unprognostic (7.85e-2)" "unprognostic (1.71e-1)" "unprognostic (8.53e-3)" "unprognostic (2.92e-2)" "unprognostic (2.21e-1)" "prognostic favorable (5.53e-4)" "unprognostic (5.73e-2)" "unprognostic (2.98e-1)" "unprognostic (1.02e-3)" "unprognostic (1.91e-1)" "prognostic favorable (2.37e-8)" "unprognostic (5.64e-2)" "unprognostic (1.67e-1)" "unprognostic (1.72e-1)" "unprognostic (2.95e-1)" 8.0 5.6 3.9 5.5 6.2 13.5 8.6 4.1 5.7 6.9 3.0 6.8 10.3 6.3 7.1 10.0 5.2 6.9 10.0 3.4 4.3 8.0 7.5 5.4 8.6 5.4 4.9 4.7 10.8 8.8 3.8 3.7 5.1 6.2 6.3 10.1 6.7 5.0 15.7 10.8 7.3 3.8 4.7 5.9 6.3 15.4 4.2 6.3 12.9 8.9 7.6 7.2 4.2 9.7 18.8 6.7 8.5 5.6 7.2 11.8 18.8 5.9 8.5 11.4 13.3 9.5 10.4 21.1 5.9 8.8 5.4 10.9 2.3 6.3 6.8 10.9 5.0 9.1 5.4 22.5 5.6 20.6 17.6 12.0 11.3 3.5 6.5 3.0 8.9 14.3 5.4 25.9 8.0 14.2 5.2 7.7 6.2 14.0 7.7 10.2 9.6 8.7 9.1 20.4 11.2 9.1 6.9 14.5 13.4 3.1 18.6 10.4 4.2 11.3 15.4 5.3 7.4 13.2 12.4 12.2 3.4 10.2 10.4 20.5 13.1 19.8 14.3 15.6 12.4 19.3 11.7 13.5 9.9 17.1 13.8 15.4 2.5 12.3 20.4 19.0 14.5 12.5 3.9 6.2 4.1 5.7 3.4 4.3 5.4 4.9 5.1 4.7 4.2 9.7 9.4 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 60.5 0.0 0.0 0.0 0.0 36.6 12.5 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 24.6 6.3 0.0 0.0 0.0 0.0 0.0 0.0 28.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 41.7 1.9 0.0 0.0 0.0 DMRTA2 ENSG00000142700 "DMRT like family A2" Q96SC8 1 50417550-50423443 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 2.6;esophagus: 1.5;pituitary gland: 2.0;testis: 1.8" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 2.9;Basal squamous epithelial cells: 17.6;Early spermatids: 10.8;Squamous epithelial cells: 5.9" "Cancer enhanced" "Detected in many" "glioma: 5.3" "Region enhanced" "Detected in single" "white matter: 2.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.1;HBEC3-KT: 3.3;RH-30: 11.7;SH-SY5Y: 2.4;SiHa: 2.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA043098, HPA062958" Uncertain Approved Nucleoplasm,Mitochondria "Intracellular and membrane" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 61: Squamous epithelial cells - Keratinization" Mitochondria Nucleoplasm "HPA043098: AB_10796684, HPA062958: AB_2684911" "unprognostic (1.60e-1)" "unprognostic (4.56e-3)" "unprognostic (2.62e-1)" "unprognostic (3.07e-1)" "unprognostic (3.03e-2)" "unprognostic (2.75e-2)" "unprognostic (1.15e-2)" "unprognostic (3.29e-1)" "unprognostic (6.89e-2)" "unprognostic (4.79e-1)" "unprognostic (7.47e-2)" "unprognostic (1.21e-3)" "unprognostic (7.08e-3)" "unprognostic (4.16e-2)" "unprognostic (7.85e-2)" "unprognostic (2.68e-3)" 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.4 0.4 0.0 0.4 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.0 2.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 1.4 0.0 0.9 3.3 0.0 0.0 0.1 0.8 0.1 0.0 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 2.4 2.4 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.4 0.4 0.3 0.2 0.6 0.5 0.3 0.2 0.8 2.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.9 17.6 0.0 0.1 0.0 1.3 0.0 1.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 10.8 0.1 0.1 0.1 1.2 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 2.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.2 0.2 1.3 1.0 5.9 0.0 0.0 0.0 0.0 0.1 0.0 DNAAF3 "C19orf51, CILD2, FLJ36139, FLJ40069, PCD, PF22" ENSG00000167646 "Dynein axonemal assembly factor 3" Q8N9W5 19 55158661-55166722 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "fallopian tube: 40.8;testis: 65.4" "Group enriched" "Detected in many" 5 "Early spermatids: 395.2;Late spermatids: 722.0" "Cancer enhanced" "Detected in many" "endometrial cancer: 4.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEK 293: 26.2;HEL: 31.6;K-562: 25.3;U-937: 18.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA056220 Approved "Nuclear bodies,Mitochondria" No No "Cluster 49: Ciliated cells - Cilium organization" "Cluster 36: HEL - Hemostasis" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "Nuclear bodies" "HPA056220: AB_2683071" "unprognostic (1.71e-2)" "unprognostic (2.67e-2)" "unprognostic (6.10e-2)" "unprognostic (9.93e-3)" "unprognostic (1.77e-1)" "unprognostic (1.87e-1)" "unprognostic (2.22e-2)" "unprognostic (1.82e-1)" "unprognostic (5.36e-2)" "unprognostic (2.26e-1)" "unprognostic (2.15e-1)" "unprognostic (1.68e-1)" "prognostic unfavorable (1.83e-5)" "unprognostic (1.35e-2)" "unprognostic (1.31e-1)" "unprognostic (2.35e-2)" "unprognostic (8.03e-2)" 0.4 1.8 1.5 0.0 1.2 0.0 0.6 0.9 0.7 2.5 6.1 0.3 0.1 0.9 3.4 0.6 40.8 0.6 5.0 1.5 2.3 2.7 0.6 4.3 0.1 4.0 8.2 0.2 1.6 3.5 0.7 0.1 4.7 0.3 0.1 0.4 0.4 0.9 0.1 0.9 0.3 0.2 3.1 0.3 0.3 65.4 1.5 0.5 2.3 0.0 0.1 0.1 0.4 2.1 8.8 6.6 0.6 6.7 0.1 0.0 0.6 0.1 0.2 1.0 0.7 0.3 4.0 10.5 2.5 0.3 1.9 10.1 1.5 3.0 0.4 0.0 26.2 31.6 0.5 0.5 0.2 13.6 3.1 0.2 4.0 1.7 2.2 0.9 0.5 4.7 25.3 13.9 0.4 5.9 0.4 0.3 0.5 9.5 15.0 16.5 1.0 3.2 5.4 0.2 0.8 2.6 1.1 1.1 1.6 0.2 8.3 0.4 1.0 0.8 3.9 4.0 0.2 0.4 2.5 0.6 4.9 18.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.5 1.2 0.9 0.7 1.5 2.3 4.0 8.2 4.7 3.1 1.5 2.1 0.2 0.0 0.5 0.0 0.0 3.2 0.0 4.7 4.6 0.0 1.1 0.6 3.0 1.5 7.5 7.3 0.0 0.0 0.0 0.3 7.9 2.7 395.2 55.8 0.5 0.6 0.0 0.0 0.5 1.0 0.1 1.2 0.0 1.3 0.0 1.9 0.7 0.4 0.2 0.0 0.5 0.5 12.2 0.0 0.4 722.0 4.4 4.2 0.0 0.0 0.0 2.1 0.0 0.5 0.1 0.2 0.1 3.0 0.0 0.1 0.0 5.1 75.2 0.0 0.0 0.0 2.3 104.8 18.6 0.3 1.3 0.0 0.1 1.1 0.4 0.2 DOCK8 "FLJ00026, FLJ00152, FLJ00346, ZIR8" ENSG00000107099 "Dedicator of cytokinesis 8" Q8NF50 9 214854-465259 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 45.0;lymphoid tissue: 64.8" "Cell type enhanced" "Detected in many" "Microglial cells: 506.8;monocytes: 134.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 173.6" "Group enriched" "Detected in all" 4 "dendritic cells: 53.0;granulocytes: 173.6;monocytes: 84.2" "Cell line enhanced" "Detected in many" "Daudi: 52.9;HL-60: 53.3;MOLT-4: 50.1;NB-4: 83.7;REH: 61.9;RT4: 54.3;THP-1: 158.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003218, HPA073349" Enhanced Approved Nucleoplasm,Centrosome,Mitochondria,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Centrosome "Nucleoplasm, Mitochondria, Cytosol" "HPA003218: AB_1078695, HPA073349: " "unprognostic (1.56e-1)" "unprognostic (5.90e-2)" "unprognostic (7.75e-2)" "unprognostic (7.55e-3)" "unprognostic (3.31e-1)" "unprognostic (6.28e-3)" "unprognostic (1.79e-1)" "unprognostic (8.12e-2)" "unprognostic (2.72e-2)" "unprognostic (6.72e-2)" "unprognostic (1.90e-1)" "unprognostic (3.89e-2)" "prognostic favorable (9.21e-6)" "unprognostic (2.91e-1)" "unprognostic (3.91e-2)" "unprognostic (3.91e-1)" "prognostic favorable (6.89e-6)" 11.0 13.3 4.3 35.7 4.4 42.2 7.3 5.2 3.9 4.3 45.0 7.3 7.3 3.0 2.9 7.2 4.3 14.6 2.0 4.0 5.9 16.5 6.1 19.7 51.1 8.8 7.6 2.0 4.2 7.7 2.6 15.3 9.1 5.1 7.3 4.5 4.6 2.8 1.0 3.0 15.4 6.2 9.3 45.6 9.5 7.5 8.8 64.8 4.9 2.5 49.6 14.8 3.3 12.8 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 0.0 1.6 1.4 52.9 3.9 0.0 0.0 2.3 0.8 0.3 0.0 18.2 2.3 0.1 0.0 0.2 0.0 53.3 7.1 0.2 9.3 0.0 0.2 0.0 0.0 0.0 11.8 25.9 0.0 3.2 50.1 83.7 0.2 0.2 0.7 61.9 0.1 21.3 0.2 54.3 0.1 0.0 0.0 0.6 3.6 1.0 1.4 158.0 10.2 0.0 0.4 0.7 0.1 10.3 0.1 0.0 0.1 33.3 0.9 65.1 56.9 73.5 12.2 52.0 10.2 25.2 15.7 13.8 53.0 23.2 11.3 11.1 173.6 24.1 84.2 13.8 15.6 22.6 4.3 4.4 5.2 3.9 4.0 5.9 8.8 7.6 9.1 9.3 8.8 12.8 5.0 9.6 33.5 2.3 112.6 6.4 2.5 1.2 45.5 3.6 12.3 10.8 2.3 18.6 4.9 7.3 77.2 70.9 101.9 1.5 1.9 1.0 33.4 1.9 0.7 9.8 8.4 35.1 1.9 6.5 4.3 5.3 12.8 3.2 24.6 12.7 2.9 2.6 58.4 0.0 4.2 12.9 2.0 115.0 49.4 14.8 3.1 107.7 8.8 506.8 134.3 1.1 74.2 4.5 2.2 1.4 24.9 0.4 94.6 1.5 1.2 12.8 8.0 4.2 13.1 30.2 20.6 22.1 13.3 9.4 3.8 42.7 111.6 1.1 1.3 3.4 DOP1B "C21orf5, DOPEY2, KIAA0933" ENSG00000142197 "DOP1 leucine zipper like protein B" Q9Y3R5 21 36156782-36294274 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 5.2;dendritic cells: 3.8;Extravillous trophoblasts: 11.4;Hofbauer cells: 16.7;Syncytiotrophoblasts: 8.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 19.8" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072065 Enhanced Approved Nucleoplasm,Mitochondria Yes No "Cluster 19: B-cells - Humoral immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Mitochondria "HPA072065: AB_2686486" "prognostic unfavorable (7.08e-4)" "unprognostic (7.68e-2)" "unprognostic (2.50e-2)" "unprognostic (1.99e-1)" "unprognostic (1.84e-1)" "unprognostic (1.66e-2)" "unprognostic (1.04e-2)" "unprognostic (1.01e-1)" "unprognostic (2.38e-1)" "unprognostic (1.36e-1)" "unprognostic (3.13e-2)" "unprognostic (4.35e-2)" "unprognostic (3.01e-2)" "unprognostic (2.59e-2)" "unprognostic (1.39e-1)" "unprognostic (1.06e-1)" "unprognostic (2.85e-1)" 3.5 1.7 2.9 5.6 4.8 24.2 5.8 19.8 8.0 4.6 0.0 15.4 12.6 2.3 3.0 11.8 4.2 4.1 4.5 3.6 1.0 3.2 9.1 4.9 4.7 3.6 1.1 1.6 4.6 30.4 2.3 3.1 4.5 12.1 15.1 1.6 19.3 3.4 15.9 7.1 11.7 3.8 0.1 5.5 20.5 3.5 2.1 6.5 4.0 13.5 6.3 4.0 5.9 3.4 25.9 5.4 4.0 6.8 4.4 8.4 38.2 12.0 14.2 16.7 10.4 3.8 2.0 4.8 1.8 9.0 12.7 5.2 7.8 2.8 13.5 8.8 7.0 11.0 1.2 1.4 3.9 10.8 5.5 2.9 5.5 10.9 2.9 10.0 7.1 11.2 3.5 7.6 5.0 29.0 8.7 11.1 3.3 30.4 5.6 15.4 2.3 23.7 8.8 10.2 10.7 6.1 8.0 35.9 10.1 5.5 13.1 13.2 12.2 6.4 1.7 8.4 9.8 5.7 15.0 2.2 9.2 23.0 3.7 1.0 3.0 6.1 2.6 2.7 1.4 7.3 1.7 1.5 1.9 10.5 1.1 0.9 4.8 1.0 2.4 5.9 1.4 1.4 2.9 4.8 19.8 8.0 3.6 1.0 3.6 1.1 4.5 0.1 2.1 3.4 2.8 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 1.9 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 11.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 8.1 0.6 0.0 0.0 0.0 DPF1 "BAF45b, NEUD4, neuro-d4" ENSG00000011332 "Double PHD fingers 1" Q92782 19 38211006-38229714 "Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 23.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 17.9;Early spermatids: 25.4;Excitatory neurons: 24.6;Horizontal cells: 45.4;Inhibitory neurons: 16.3;Late spermatids: 23.4" "Group enriched" "Detected in some" 5 "glioma: 5.6;testis cancer: 3.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 19.7;SCLC-21H: 22.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049148 Enhanced Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Cytosol" Mitochondria "HPA049148: AB_2680653" "unprognostic (7.72e-2)" "unprognostic (2.33e-1)" "unprognostic (5.38e-2)" "unprognostic (4.11e-3)" "unprognostic (8.16e-2)" "unprognostic (2.21e-1)" "unprognostic (1.29e-4)" "unprognostic (1.40e-2)" "unprognostic (2.72e-1)" "unprognostic (5.49e-2)" "unprognostic (4.30e-3)" "unprognostic (2.87e-2)" "unprognostic (1.11e-16)" "unprognostic (2.56e-1)" "unprognostic (3.75e-1)" "unprognostic (6.96e-2)" "unprognostic (8.20e-4)" 0.1 0.3 12.7 0.4 14.9 0.1 0.1 2.2 23.4 0.2 0.0 0.2 0.0 0.2 0.0 0.1 0.2 0.0 0.4 16.9 9.9 0.1 0.0 0.3 0.1 1.9 4.4 0.3 0.1 0.0 2.5 0.1 2.4 0.1 0.0 2.4 0.2 0.0 0.2 0.3 0.1 0.2 2.0 0.1 0.1 2.4 9.5 0.2 0.0 0.0 0.1 0.1 0.1 14.8 4.6 3.8 15.8 11.7 1.1 0.8 1.6 4.8 2.7 8.0 6.7 2.7 0.4 7.5 3.2 3.7 3.2 2.8 19.7 2.6 3.6 7.2 3.9 2.5 2.0 1.1 0.4 1.9 2.1 0.9 0.1 4.7 1.5 1.0 1.5 5.5 5.6 0.4 7.7 6.4 4.1 0.5 2.9 1.3 4.4 7.5 8.0 1.6 0.8 1.4 22.9 7.8 5.4 0.5 1.0 1.9 2.4 0.4 1.8 11.5 3.7 2.8 4.4 2.9 10.3 9.9 6.1 2.6 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.7 14.9 2.2 23.4 16.9 9.9 1.9 4.4 2.4 2.0 9.5 14.8 0.4 0.0 0.0 3.3 0.1 2.3 0.1 1.1 0.0 17.9 0.2 0.6 1.2 0.0 0.1 0.0 8.4 0.1 0.0 0.1 0.0 0.0 25.4 1.5 2.2 0.9 0.0 0.0 24.6 0.0 2.0 1.5 0.0 0.7 0.0 4.3 0.4 0.0 0.2 45.4 16.3 0.0 0.0 0.3 0.4 23.4 0.6 0.1 0.0 1.0 0.0 3.3 0.0 12.5 4.8 0.1 0.0 2.6 0.0 0.1 0.0 0.1 1.4 3.1 0.0 0.7 1.9 6.7 12.6 0.0 1.1 0.1 0.2 1.6 0.0 0.1 DPY19L2 "FLJ32949, SPATA34" ENSG00000177990 "Dpy-19 like 2" Q6NUT2 12 63558913-63668939 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 65.6" "Group enriched" "Detected in many" 4 "Early spermatids: 329.9;Excitatory neurons: 124.1;Inhibitory neurons: 137.2;Late spermatids: 363.0;Oligodendrocyte precursor cells: 124.1;Spermatocytes: 143.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-266/84: 9.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA071264, HPA078305" Enhanced Approved Nucleoplasm,Mitochondria Yes No "Cluster 16: MAIT-cells - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" Mitochondria Nucleoplasm "HPA071264: AB_2686375, HPA078305: " "unprognostic (1.97e-1)" "unprognostic (4.08e-1)" "unprognostic (4.46e-3)" "unprognostic (2.50e-2)" "unprognostic (1.64e-1)" "unprognostic (1.17e-4)" "unprognostic (2.28e-2)" "unprognostic (2.14e-3)" "unprognostic (1.53e-1)" "unprognostic (3.64e-1)" "unprognostic (3.99e-3)" "unprognostic (1.97e-1)" "unprognostic (6.31e-3)" "unprognostic (4.22e-3)" "unprognostic (5.88e-2)" "unprognostic (8.90e-3)" "unprognostic (1.79e-1)" 6.7 5.3 4.0 0.5 3.9 3.0 4.7 7.0 6.9 11.4 6.6 5.2 0.6 7.8 4.1 1.4 6.4 2.8 19.2 3.0 4.3 12.7 0.2 1.3 0.9 2.4 3.0 11.0 2.7 9.0 10.5 1.2 1.5 9.3 1.3 14.4 1.6 4.7 0.5 1.6 1.7 3.5 0.8 1.7 2.9 65.6 3.3 0.7 13.1 0.6 0.6 6.3 5.1 4.2 1.0 2.6 2.2 5.4 0.6 0.0 0.2 1.8 1.8 2.4 3.1 0.4 0.8 2.8 1.8 0.7 2.9 0.4 2.7 0.3 3.6 1.5 1.7 4.6 1.4 1.7 0.5 3.4 1.4 1.5 0.1 1.1 0.0 6.1 0.8 2.2 1.9 2.9 3.9 1.7 0.2 1.4 2.1 0.4 2.4 0.0 1.8 0.0 4.6 0.5 7.0 0.7 0.6 0.2 1.0 0.9 1.9 0.9 0.5 3.2 4.2 0.5 4.6 7.5 9.3 0.0 3.4 1.6 3.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.1 4.0 3.9 7.0 6.9 3.0 4.3 2.4 3.0 1.5 0.8 3.3 4.2 6.7 3.2 0.0 23.2 0.2 0.5 2.9 0.1 2.2 49.6 1.9 1.8 32.3 1.5 3.8 12.9 14.6 2.0 0.3 0.1 5.9 0.4 329.9 5.6 7.1 1.7 0.0 7.2 124.1 0.0 1.3 2.2 0.5 2.1 2.5 1.2 1.4 0.1 0.3 3.3 137.2 0.1 6.1 0.0 0.4 363.0 7.2 0.4 7.2 11.2 0.1 9.2 0.0 124.1 5.0 0.2 0.0 8.6 0.5 2.9 0.0 6.4 11.6 6.7 26.3 3.8 19.9 143.3 4.9 0.2 0.4 1.4 0.8 3.6 0.1 1.1 DPYSL4 "CRMP3, DRP-4, ULIP4" ENSG00000151640 "Dihydropyrimidinase like 4" O14531 10 132186948-132205759 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.9;heart muscle: 33.7;retina: 15.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 64.9;Cardiomyocytes: 20.1;Cone photoreceptor cells: 58.4;Horizontal cells: 33.7;Oligodendrocytes: 18.4" "Cancer enhanced" "Detected in many" "glioma: 13.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 53.2;AN3-CA: 70.0;SH-SY5Y: 72.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049066 Approved Approved Vesicles,Mitochondria NA NA "Cluster 32: T-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 62: Horizontal cells - Visual perception" "Vesicles, Mitochondria" "HPA049066: AB_2680619" "unprognostic (6.27e-2)" "unprognostic (2.07e-2)" "unprognostic (1.35e-1)" "unprognostic (1.81e-1)" "unprognostic (3.95e-1)" "unprognostic (5.99e-2)" "unprognostic (8.36e-5)" "unprognostic (1.72e-1)" "unprognostic (8.91e-2)" "unprognostic (1.08e-2)" "unprognostic (3.81e-2)" "unprognostic (6.36e-2)" "unprognostic (7.47e-6)" "unprognostic (3.04e-3)" "unprognostic (1.66e-1)" "unprognostic (2.75e-2)" "prognostic unfavorable (3.11e-4)" 1.3 2.2 18.4 0.7 18.6 0.1 1.5 10.3 25.9 2.5 2.4 1.6 0.1 3.3 0.7 0.6 1.5 0.7 33.7 20.3 12.6 0.6 0.3 1.2 0.3 14.8 15.0 5.3 0.9 0.0 10.4 0.2 15.1 4.9 0.0 15.9 2.6 2.0 2.0 1.2 0.9 1.1 12.1 1.2 1.3 7.9 16.4 0.0 1.0 0.2 0.2 1.0 1.3 18.1 0.1 15.2 53.2 70.0 0.1 0.4 0.0 4.6 0.6 2.9 0.6 0.0 0.4 0.0 1.8 2.4 5.1 0.0 10.4 10.3 0.3 0.0 2.0 0.0 0.1 5.7 9.3 0.0 10.6 4.7 4.9 1.7 0.2 0.9 5.4 0.0 0.0 0.5 7.7 4.5 0.0 0.0 9.1 0.9 5.1 0.0 0.0 8.7 0.0 1.1 8.3 72.0 1.7 0.1 9.7 3.1 0.2 0.1 9.0 13.1 21.7 0.0 12.8 0.1 3.9 0.0 22.0 0.0 1.4 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.5 0.1 0.0 0.3 0.1 0.0 0.0 0.1 18.4 18.6 10.3 25.9 20.3 12.6 14.8 15.0 15.1 12.1 16.4 18.1 0.3 0.0 0.0 7.2 0.1 0.5 0.5 0.1 0.6 64.9 0.4 0.6 20.1 0.0 0.1 0.0 58.4 0.0 0.1 0.0 0.0 0.3 5.3 0.1 5.0 1.2 1.8 0.0 12.2 0.0 0.1 2.7 2.0 0.3 0.0 0.7 0.0 0.0 0.2 33.7 13.6 0.0 0.0 0.0 0.8 9.0 4.1 0.1 1.8 0.0 0.1 7.5 0.0 12.1 18.4 0.5 0.0 4.5 0.0 0.7 0.0 0.0 0.0 13.8 0.0 1.0 5.7 7.0 5.2 0.3 0.1 0.0 0.5 4.5 0.0 0.2 DTNB ENSG00000138101 "Dystrobrevin beta" O60941 2 25377198-25673647 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 36.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 176.8;Inhibitory neurons: 214.1;Oligodendrocyte precursor cells: 137.7;Oligodendrocytes: 343.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" HPA061357 Uncertain Approved Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA061357: AB_2684489" "unprognostic (1.14e-1)" "unprognostic (1.39e-2)" "unprognostic (3.17e-2)" "unprognostic (7.40e-2)" "unprognostic (1.17e-1)" "unprognostic (1.16e-2)" "prognostic unfavorable (2.54e-4)" "unprognostic (1.78e-2)" "unprognostic (3.67e-3)" "unprognostic (3.98e-2)" "unprognostic (9.45e-2)" "unprognostic (4.67e-2)" "prognostic favorable (3.47e-4)" "unprognostic (1.86e-1)" "unprognostic (1.40e-1)" "unprognostic (3.16e-2)" "unprognostic (6.49e-2)" 2.1 2.1 7.8 1.6 6.7 2.9 9.7 3.4 12.1 4.2 0.0 1.7 1.2 2.8 10.1 4.5 4.6 3.3 2.0 12.4 3.6 4.2 3.4 4.3 2.5 4.9 1.7 4.4 7.7 9.9 5.8 1.9 4.5 8.4 1.0 5.0 36.0 5.1 2.7 4.5 1.6 1.2 0.1 2.7 5.6 6.7 2.9 4.0 11.1 1.5 1.9 3.5 4.0 5.6 10.7 9.1 6.6 7.5 4.0 5.2 0.2 3.2 4.2 4.0 5.3 3.5 2.6 5.5 1.3 2.5 5.0 3.7 4.6 13.1 2.2 8.2 11.1 4.5 2.9 10.0 2.9 5.4 4.1 3.6 10.9 4.2 7.2 4.9 5.5 10.5 0.4 8.0 3.0 10.9 8.5 4.6 7.3 2.9 5.4 7.0 11.5 9.7 4.9 9.7 8.9 13.7 10.3 16.2 12.9 3.6 8.7 3.3 2.3 1.6 7.3 2.4 5.7 14.6 6.8 10.0 4.6 9.5 5.7 0.4 1.6 5.7 4.1 0.9 4.4 4.4 5.0 3.7 0.5 5.8 5.0 3.3 3.2 4.1 0.4 0.9 5.2 2.0 7.8 6.7 3.4 12.1 12.4 3.6 4.9 1.7 4.5 0.1 2.9 5.6 3.9 9.6 12.8 53.2 12.6 8.0 26.6 16.4 44.3 9.4 20.3 18.9 2.3 7.2 9.3 14.7 6.2 3.7 4.2 0.9 11.7 4.0 3.1 7.2 4.2 4.7 3.0 4.4 176.8 11.6 1.5 3.2 15.8 12.1 1.3 4.6 5.0 5.6 33.6 21.9 214.1 2.8 14.2 7.8 1.7 6.9 1.5 4.9 12.4 83.4 3.2 18.5 7.2 137.7 343.3 9.5 1.4 2.6 8.7 17.9 0.3 9.3 2.2 9.9 6.6 1.9 3.2 12.6 27.9 15.7 2.0 2.1 10.8 2.3 1.3 17.7 DTYMK "CDC8, TMPK, TYMK" ENSG00000168393 "Deoxythymidylate kinase" P23919 2 241675747-241686944 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Nucleotide biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 108.6;Extravillous trophoblasts: 149.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042593, HPA042719" Approved Approved Mitochondria NA NA 7000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Mitochondria "HPA042593: AB_10959590, HPA042719: AB_10960633" "unprognostic (1.90e-1)" "unprognostic (6.95e-2)" "unprognostic (4.14e-1)" "unprognostic (8.61e-2)" "unprognostic (1.89e-1)" "unprognostic (9.45e-2)" "prognostic unfavorable (1.73e-5)" "unprognostic (1.44e-2)" "unprognostic (2.64e-2)" "unprognostic (5.50e-2)" "unprognostic (2.60e-2)" "unprognostic (6.94e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (7.13e-2)" "unprognostic (6.81e-2)" "unprognostic (5.07e-2)" "unprognostic (9.19e-2)" 12.2 16.0 15.6 15.6 17.1 37.0 11.8 16.2 19.8 11.2 16.5 15.1 13.2 10.8 6.1 19.1 10.2 8.6 10.6 14.5 15.0 14.9 18.8 9.7 24.8 16.8 16.0 8.2 9.5 7.5 5.0 11.1 16.1 11.1 12.2 4.3 9.8 7.4 8.1 18.8 14.0 13.4 15.3 17.2 13.3 8.2 16.8 24.1 8.7 6.4 19.2 10.6 11.2 17.2 102.6 112.3 93.6 120.1 30.2 33.3 103.2 82.1 63.2 110.8 125.6 54.8 120.1 48.3 24.6 66.8 126.8 84.4 87.8 102.2 56.7 118.8 104.6 103.9 88.3 105.1 26.3 69.1 83.1 23.7 27.3 102.7 42.4 32.1 104.8 74.4 123.6 38.4 114.1 112.6 132.2 125.0 100.7 113.1 94.2 111.4 139.8 71.8 62.3 59.5 115.0 74.0 53.4 81.5 67.9 27.0 74.2 120.0 66.5 147.5 110.4 99.0 152.5 47.3 49.1 144.6 122.4 112.2 184.9 20.5 26.2 17.4 30.4 46.7 29.6 35.6 28.5 32.6 19.7 36.7 28.1 25.0 4.2 32.6 37.1 38.5 42.1 28.5 15.6 17.1 16.2 19.8 14.5 15.0 16.8 16.0 16.1 15.3 16.8 17.2 28.9 9.6 5.8 8.1 21.4 15.2 17.7 47.7 16.5 19.1 36.3 44.8 11.0 24.3 22.2 25.8 2.1 79.5 24.0 22.9 21.5 39.6 2.1 17.6 25.0 29.2 14.4 108.6 3.3 34.1 149.1 26.9 25.5 22.3 15.2 52.3 23.9 22.3 84.9 5.0 4.7 35.7 36.7 17.0 13.9 2.1 16.4 21.7 23.2 5.6 39.3 23.0 38.1 6.0 9.2 33.7 10.6 19.2 37.6 21.7 12.7 37.7 12.9 17.4 26.3 21.4 31.2 27.5 63.4 32.6 11.9 27.5 17.4 28.2 52.2 19.5 DYNC2H1 "DHC1b, DHC2, DNCH2, DYH1B, hdhc11" ENSG00000187240 "Dynein cytoplasmic 2 heavy chain 1" Q8NCM8 11 103109410-103479863 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein, Motor protein" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 173.7;Cone photoreceptor cells: 112.6;Endometrial ciliated cells: 124.0;Excitatory neurons: 164.7;Inhibitory neurons: 101.8;Respiratory ciliated cells: 171.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 21.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039015, HPA039016" Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 30: Epithelial cell lines - Translation" "Cluster 49: Ciliated cells - Cilium organization" Mitochondria "Nucleoplasm, Cytosol" "HPA039015: AB_2676309, HPA039016: AB_10673410" "unprognostic (3.11e-1)" "unprognostic (2.60e-1)" "unprognostic (1.28e-2)" "unprognostic (1.54e-1)" "unprognostic (7.11e-2)" "unprognostic (2.08e-1)" "unprognostic (4.14e-3)" "unprognostic (2.07e-2)" "unprognostic (2.05e-1)" "unprognostic (4.10e-2)" "unprognostic (2.87e-2)" "unprognostic (7.13e-2)" "prognostic favorable (8.49e-5)" "unprognostic (3.75e-3)" "unprognostic (1.62e-1)" "unprognostic (3.88e-2)" "unprognostic (4.11e-3)" 4.2 3.0 5.0 1.2 5.2 0.3 3.5 5.6 10.2 5.1 14.6 3.2 1.6 4.6 3.7 1.6 6.5 3.2 2.0 4.1 6.1 3.7 0.8 2.8 0.9 8.3 8.9 5.6 2.9 6.7 6.8 1.4 6.3 2.6 0.7 10.5 2.6 2.5 0.8 2.8 2.1 2.3 5.5 1.9 2.2 7.9 6.7 1.8 4.6 1.5 0.7 3.3 3.0 5.9 1.3 2.7 7.0 3.3 9.5 21.2 0.4 4.0 6.4 6.5 7.0 1.6 1.5 0.0 5.5 8.0 3.1 5.5 5.5 7.7 5.3 0.0 4.6 1.2 4.8 0.2 9.3 2.2 1.3 13.6 2.8 14.9 16.9 10.3 2.7 1.4 0.2 0.0 8.6 5.4 0.7 0.7 1.9 0.0 7.7 0.0 5.9 0.1 7.5 0.9 4.6 3.6 6.5 1.7 3.1 1.7 6.8 1.5 6.4 7.9 3.3 7.7 3.0 0.0 0.0 0.1 2.3 6.7 2.4 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.7 0.0 0.0 0.0 0.0 5.0 5.2 5.6 10.2 4.1 6.1 8.3 8.9 6.3 5.5 6.7 5.9 12.7 0.0 13.1 173.7 2.3 6.6 13.4 17.3 9.6 25.9 8.2 9.7 10.1 4.3 18.0 27.6 112.6 0.3 2.1 0.2 1.9 7.0 26.1 124.0 43.7 11.1 17.3 1.3 164.7 3.4 0.5 32.0 5.6 7.5 3.8 15.4 9.3 0.8 2.5 32.0 101.8 1.0 4.1 0.8 5.8 11.1 20.8 3.1 8.8 45.0 0.9 16.5 1.0 86.0 72.6 10.5 2.9 18.4 3.3 4.9 0.9 16.9 171.0 85.1 19.7 40.8 18.5 90.6 11.6 5.0 5.5 0.5 5.0 23.5 1.7 5.9 EARS2 "KIAA1970, MSE1, mtGlnRS" ENSG00000103356 "Glutamyl-tRNA synthetase 2, mitochondrial" Q5JPH6 16 23520754-23557731 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, RNA-binding" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043289, HPA043633" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoplasm "HPA043289: AB_10963932, HPA043633: AB_10959901" "unprognostic (3.10e-2)" "unprognostic (1.60e-1)" "unprognostic (3.65e-3)" "unprognostic (4.20e-1)" "unprognostic (3.57e-1)" "unprognostic (4.64e-2)" "unprognostic (2.73e-1)" "unprognostic (2.91e-2)" "unprognostic (1.16e-1)" "unprognostic (2.99e-2)" "prognostic unfavorable (7.20e-4)" "unprognostic (8.09e-2)" "prognostic favorable (3.16e-6)" "unprognostic (2.48e-1)" "unprognostic (1.80e-1)" "unprognostic (1.19e-1)" "unprognostic (4.29e-2)" 3.7 7.6 3.3 1.2 3.5 1.5 4.0 2.7 4.0 2.9 3.6 3.7 1.1 3.7 3.0 5.2 3.0 1.0 5.3 3.3 3.6 4.9 9.9 3.1 1.8 3.3 2.5 3.3 5.6 4.8 3.5 2.5 2.6 3.0 2.3 1.9 4.6 1.4 4.2 5.6 2.9 2.0 1.5 3.3 4.1 3.8 3.5 2.5 4.3 3.8 2.4 3.3 3.3 3.2 2.6 8.3 2.4 4.8 2.9 3.8 3.9 3.2 3.1 3.6 2.4 5.0 2.9 4.8 2.6 3.3 1.8 2.9 9.6 6.4 4.7 2.9 7.7 2.4 5.3 7.1 2.4 3.4 2.1 3.2 4.4 2.4 4.7 4.5 1.4 5.2 7.0 2.5 2.6 5.5 2.1 2.3 7.5 4.4 2.8 4.1 4.5 8.0 5.5 3.8 5.0 4.1 2.1 5.0 2.7 6.3 5.9 3.0 2.3 3.1 2.1 3.1 3.4 5.1 3.7 3.4 4.1 4.0 4.3 0.1 0.8 0.0 1.0 1.5 1.6 0.8 1.4 1.1 1.7 1.0 1.3 1.1 0.4 1.8 1.1 1.6 1.7 1.3 3.3 3.5 2.7 4.0 3.3 3.6 3.3 2.5 2.6 1.5 3.5 3.2 1.8 9.6 5.9 5.2 3.8 2.2 4.0 4.0 4.0 3.8 6.2 4.7 11.6 2.8 2.9 3.7 2.1 15.1 2.3 2.5 5.9 7.0 2.9 3.3 4.9 3.2 5.4 9.4 8.3 3.5 12.3 4.3 4.1 3.4 5.7 6.5 3.6 11.4 7.1 8.4 7.9 4.3 2.0 3.2 2.5 2.5 2.5 3.4 5.4 3.7 5.3 2.6 4.1 4.0 4.7 3.7 1.7 1.9 8.8 4.9 1.6 8.6 5.3 3.9 0.0 2.7 3.4 5.8 9.8 6.5 3.0 11.4 3.3 12.6 6.2 3.2 ECHDC2 FLJ10948 ENSG00000121310 "Enoyl-CoA hydratase domain containing 2" Q86YB7 1 52895910-52927212 "Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 174.3" "Cell type enhanced" "Detected in all" "Hepatocytes: 875.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 15.8;HHSteC: 11.0;THP-1: 10.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026731, HPA026768" Enhanced Approved Mitochondria NA NA 240000 "Cluster 35: T-regs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 2: Hepatocytes - Metabolism" Mitochondria "HPA026731: AB_1847969, HPA026768: AB_1847970" "unprognostic (2.73e-3)" "unprognostic (1.52e-2)" "unprognostic (4.08e-2)" "unprognostic (3.76e-1)" "unprognostic (7.67e-2)" "prognostic favorable (6.65e-4)" "unprognostic (1.51e-3)" "unprognostic (1.40e-3)" "unprognostic (6.11e-2)" "unprognostic (7.16e-2)" "unprognostic (2.98e-3)" "unprognostic (4.40e-2)" "unprognostic (5.47e-2)" "unprognostic (5.12e-2)" "unprognostic (2.93e-1)" "unprognostic (3.62e-1)" "prognostic favorable (2.70e-4)" 24.1 35.2 5.9 1.2 6.0 2.7 24.9 7.5 7.9 18.1 7.2 18.0 16.7 17.2 5.5 28.2 23.1 5.1 27.6 5.6 5.7 50.6 174.3 12.8 2.3 5.6 5.8 29.1 23.2 14.3 14.6 4.5 5.7 24.0 3.5 5.0 19.0 8.4 29.9 17.1 17.3 2.4 5.5 9.3 29.1 7.0 6.1 3.0 38.9 26.8 1.5 18.2 16.8 5.7 0.0 1.8 0.0 0.0 1.1 0.5 15.8 1.2 7.6 1.6 2.4 0.0 1.5 0.0 7.7 1.2 0.0 0.8 0.0 1.2 0.3 0.0 8.1 0.0 3.1 3.6 11.0 0.0 1.8 1.6 3.2 1.0 1.1 2.4 4.5 0.0 1.2 0.2 0.0 4.2 0.0 0.9 0.2 7.0 1.7 0.0 0.2 0.7 5.2 6.4 0.8 0.3 2.3 6.3 0.1 0.9 1.3 10.2 2.3 0.0 0.0 0.7 0.2 0.3 0.6 0.0 0.5 0.0 0.4 0.0 2.1 1.8 12.1 1.4 9.1 6.9 9.9 11.4 9.5 3.3 10.7 6.6 0.4 6.1 0.8 2.4 13.6 4.0 5.9 6.0 7.5 7.9 5.6 5.7 5.6 5.8 5.7 5.5 6.1 5.7 23.9 54.5 92.0 161.3 17.9 30.7 85.6 67.2 83.1 32.3 96.4 86.7 61.5 153.0 71.1 86.5 327.4 206.0 26.7 96.4 178.1 59.3 150.2 54.9 19.5 18.7 52.1 29.9 26.0 59.4 18.0 64.6 94.3 41.3 29.8 50.6 30.4 875.3 31.8 42.1 34.9 78.3 40.7 27.6 13.8 180.6 154.1 12.8 40.9 51.5 7.6 60.0 23.7 54.8 6.9 44.6 115.7 112.5 10.0 66.5 172.6 284.7 62.5 160.6 19.7 118.3 39.5 17.0 16.7 66.9 29.5 124.0 36.1 23.7 64.7 80.0 EFNA2 "ELF-1, EPLG6, LERK6" ENSG00000099617 "Ephrin A2" O43921 19 1285873-1301431 "Cancer-related genes, Predicted intracellular proteins, RAS pathway related proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 12.3;liver: 12.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 1.5;Cardiomyocytes: 4.9;Inhibitory neurons: 1.6;Oligodendrocyte precursor cells: 5.0;Paneth cells: 2.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.5;stomach cancer: 8.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 10.3;CACO-2: 6.2;Hep G2: 13.5;NTERA-2: 6.8;OE19: 6.0;REH: 6.8;SH-SY5Y: 13.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067567 Approved Mitochondria,Cytosol "Intracellular and membrane" NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 43: Cardiomyocytes - Nuclear processes" "Mitochondria, Cytosol" "HPA067567: AB_2732771" "unprognostic (1.98e-1)" "unprognostic (3.26e-1)" "unprognostic (2.87e-3)" "unprognostic (1.96e-2)" "unprognostic (4.04e-2)" "unprognostic (3.90e-1)" "unprognostic (7.19e-2)" "unprognostic (2.34e-3)" "unprognostic (3.58e-2)" "unprognostic (6.82e-2)" "unprognostic (8.48e-2)" "unprognostic (1.12e-1)" "unprognostic (1.61e-3)" "unprognostic (1.17e-1)" "unprognostic (1.03e-1)" "unprognostic (2.82e-4)" "unprognostic (1.94e-1)" 0.0 0.0 1.6 1.5 1.7 0.0 0.0 1.2 1.3 0.1 0.3 9.9 9.9 0.0 0.0 0.4 0.0 3.5 0.0 1.4 2.0 0.4 12.9 0.0 0.0 1.7 3.0 0.0 0.1 0.2 0.3 0.2 1.1 0.0 4.4 0.6 0.0 0.0 0.2 0.1 12.3 0.0 1.9 0.0 0.2 0.6 3.1 0.0 0.0 0.0 0.0 0.1 0.1 1.4 0.0 0.2 10.3 3.1 0.0 0.0 3.7 0.2 0.0 0.0 0.0 6.2 0.1 0.0 1.8 0.0 0.0 0.0 4.8 0.0 0.0 0.0 1.4 0.0 0.0 13.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.1 0.1 0.1 0.1 0.0 1.4 0.0 0.1 6.8 6.0 0.0 6.8 1.0 0.1 0.0 0.4 0.0 13.3 0.7 0.0 0.2 3.5 0.4 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.5 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 1.6 1.7 1.2 1.3 1.4 2.0 1.7 3.0 1.1 1.9 3.1 1.4 0.1 0.0 0.0 1.0 0.3 1.5 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 1.6 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 1.0 0.0 2.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.2 0.0 EIF4EBP2 ENSG00000148730 "Eukaryotic translation initiation factor 4E binding protein 2" Q13542 10 70404145-70428618 "Predicted intracellular proteins" "Translation regulation" "Protein synthesis inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019415, HPA037410, HPA061665" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Mitochondria" "CAB019415: AB_10699019, HPA037410: AB_2675461, HPA061665: AB_2684580" "unprognostic (9.57e-2)" "unprognostic (3.22e-2)" "unprognostic (2.27e-1)" "unprognostic (1.45e-2)" "unprognostic (1.05e-1)" "unprognostic (3.51e-1)" "unprognostic (3.84e-1)" "unprognostic (7.24e-2)" "unprognostic (8.24e-2)" "unprognostic (8.19e-2)" "unprognostic (2.87e-1)" "unprognostic (1.46e-1)" "prognostic favorable (6.69e-6)" "unprognostic (1.05e-1)" "unprognostic (1.62e-1)" "unprognostic (1.53e-1)" "unprognostic (4.61e-2)" 67.7 27.6 27.8 23.2 25.2 30.4 44.8 21.8 23.6 29.0 28.9 41.2 40.4 25.1 16.5 31.9 25.8 23.8 40.8 21.0 23.9 57.3 50.5 30.5 26.2 28.9 26.6 34.9 30.2 27.5 11.2 43.8 21.7 24.7 39.6 34.9 28.2 33.6 64.2 35.0 47.3 27.2 23.6 26.7 30.9 18.2 34.7 34.5 23.2 67.4 29.2 36.2 28.2 20.1 56.3 17.8 93.7 92.0 176.9 66.8 51.8 33.5 40.5 24.0 25.9 77.5 48.1 57.2 20.1 48.6 14.9 35.6 46.2 30.4 26.9 63.6 24.0 41.4 21.1 30.8 41.5 74.4 28.4 74.8 30.8 29.4 26.4 48.4 36.8 46.0 69.0 50.7 37.5 31.5 64.3 76.3 80.7 54.2 31.8 66.3 37.6 37.4 30.7 56.3 51.1 77.6 45.7 103.0 44.5 63.8 47.2 65.3 40.6 15.6 20.0 25.8 30.2 35.5 73.2 66.5 18.1 108.2 16.3 20.8 19.2 28.7 16.4 16.8 13.2 9.0 13.1 13.8 17.2 8.2 10.9 11.4 21.1 11.6 23.0 5.7 15.7 19.2 27.8 25.2 21.8 23.6 21.0 23.9 28.9 26.6 21.7 23.6 34.7 20.1 72.5 25.6 37.6 21.9 31.9 52.9 53.5 25.4 27.9 46.8 42.9 32.5 147.0 68.6 29.1 36.8 20.9 47.3 45.2 196.7 43.0 43.9 25.9 33.1 52.1 41.4 26.5 70.5 13.0 59.3 119.1 49.9 34.7 57.8 11.4 39.0 61.8 157.4 46.0 23.5 17.5 73.6 34.6 95.4 45.1 59.0 65.9 50.9 21.4 24.4 92.9 73.1 76.2 22.1 9.1 59.5 94.7 61.3 33.8 63.4 195.2 137.0 23.4 17.2 78.9 46.4 37.1 43.7 47.1 39.1 70.0 57.3 43.0 47.0 73.1 109.4 ELK3 "ERP, NET, SAP2" ENSG00000111145 "ETS transcription factor ELK3" P41970 12 96194375-96269824 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 170.7;Endothelial cells: 148.0;Hepatic stellate cells: 160.6;Respiratory ciliated cells: 103.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001600 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 13: T-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Mitochondria "HPA001600: AB_1078752" "unprognostic (3.11e-1)" "unprognostic (8.81e-3)" "unprognostic (6.38e-2)" "unprognostic (5.77e-2)" "unprognostic (7.18e-3)" "unprognostic (1.12e-1)" "unprognostic (1.15e-1)" "unprognostic (5.10e-3)" "unprognostic (7.39e-2)" "prognostic unfavorable (4.93e-4)" "unprognostic (2.29e-2)" "unprognostic (1.13e-1)" "unprognostic (1.20e-3)" "unprognostic (2.90e-3)" "unprognostic (1.61e-1)" "unprognostic (1.70e-1)" "unprognostic (2.05e-2)" 37.1 14.4 5.4 34.2 6.1 18.4 28.4 14.4 5.8 28.0 11.7 15.6 9.2 35.2 9.3 38.1 16.9 30.2 23.9 4.7 7.2 14.0 10.8 27.5 38.0 9.1 7.9 10.2 9.0 11.6 5.8 27.0 7.9 13.1 13.9 2.9 15.3 15.3 11.2 12.5 13.5 37.9 7.0 41.8 14.8 8.6 8.3 19.7 21.8 22.2 37.5 29.2 24.5 6.6 50.3 29.5 29.7 15.8 73.7 137.3 7.6 62.3 118.5 48.6 37.3 1.7 36.6 8.0 20.9 70.4 36.4 17.6 3.3 99.8 85.0 21.7 11.4 2.5 12.2 11.2 22.3 24.2 5.7 81.3 18.4 100.4 75.4 98.5 117.8 6.0 6.0 32.3 166.4 7.6 4.8 16.4 36.3 7.1 38.8 39.7 49.8 9.1 41.7 13.0 1.4 31.4 20.5 9.1 32.0 44.7 5.0 13.3 73.2 132.4 52.2 82.5 54.8 61.7 55.0 1.8 47.0 28.2 94.1 7.1 23.5 0.5 11.1 13.0 42.5 23.2 25.7 15.0 17.7 19.0 15.4 11.4 7.4 20.1 12.1 7.1 45.4 12.8 5.4 6.1 14.4 5.8 4.7 7.2 9.1 7.9 7.9 7.0 8.3 6.6 170.7 6.4 22.3 3.9 22.3 32.6 44.6 15.0 10.8 0.7 7.1 8.1 6.6 2.8 39.4 5.5 4.2 1.2 27.5 2.1 5.9 21.8 1.0 49.0 19.7 148.0 1.2 12.4 4.2 15.6 3.9 35.2 3.1 44.0 17.1 1.3 160.6 4.3 24.5 0.0 1.9 3.4 2.0 32.0 39.7 2.5 11.5 31.4 12.4 39.4 23.6 5.8 9.2 5.5 5.3 56.8 3.4 10.5 29.5 45.7 0.5 0.7 103.1 0.6 13.1 27.7 19.9 0.2 12.6 24.4 27.0 1.1 32.6 10.6 3.0 79.0 EML6 FLJ42562 ENSG00000214595 "EMAP like 6" Q6ZMW3 2 54723499-54972025 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 10.3;retina: 13.9" "Cell type enhanced" "Detected in many" "Astrocytes: 145.0;Excitatory neurons: 372.7;Inhibitory neurons: 265.1;Oligodendrocyte precursor cells: 95.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 10.9;SCLC-21H: 34.0;U-698: 35.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062808, HPA068759" Uncertain Approved Vesicles,Mitochondria NA NA "Cluster 10: Basophils - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Mitochondria Vesicles "HPA062808: AB_2684872, HPA068759: AB_2686027" "unprognostic (1.06e-1)" "unprognostic (6.89e-4)" "unprognostic (7.83e-2)" "unprognostic (9.96e-2)" "unprognostic (6.24e-2)" "unprognostic (3.26e-4)" "unprognostic (5.27e-2)" "unprognostic (1.31e-1)" "unprognostic (2.26e-1)" "unprognostic (6.27e-2)" "unprognostic (6.85e-6)" "unprognostic (5.00e-1)" "unprognostic (5.81e-2)" "unprognostic (6.37e-3)" "unprognostic (1.43e-1)" "unprognostic (1.66e-2)" "unprognostic (5.13e-3)" 0.3 3.0 1.6 4.0 1.8 0.7 0.7 1.4 3.8 0.2 0.2 0.7 0.7 0.3 1.1 0.5 0.4 0.2 0.1 2.2 2.1 1.7 0.5 0.4 7.0 1.3 1.4 0.1 0.8 1.9 3.2 1.4 1.3 0.6 0.8 13.9 0.5 0.5 1.0 0.9 2.0 0.4 0.6 2.6 0.5 1.3 1.4 0.6 2.6 0.5 10.3 0.6 0.4 2.9 0.7 2.0 0.2 1.5 1.0 0.3 2.0 0.2 0.3 0.2 0.2 0.8 0.3 10.9 0.2 0.7 0.4 0.3 1.4 0.5 0.4 1.0 0.4 0.6 0.9 5.1 0.0 0.3 0.0 0.1 0.1 0.6 1.1 0.2 0.2 6.2 0.0 2.0 0.0 1.1 2.1 0.4 0.5 0.2 2.3 0.9 0.7 0.8 0.1 1.4 34.0 4.2 0.5 0.1 0.0 0.2 0.1 0.1 0.3 0.4 2.1 0.5 0.6 7.8 2.2 35.0 1.8 3.7 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.8 1.4 3.8 2.2 2.1 1.3 1.4 1.3 0.6 1.4 2.9 0.9 0.0 1.1 145.0 7.3 3.7 1.9 0.6 1.8 28.0 1.1 0.8 2.0 0.0 3.5 3.7 56.3 0.4 0.4 0.5 0.0 0.2 24.6 2.9 0.6 1.3 2.4 0.0 372.7 0.4 0.6 1.0 2.0 1.2 0.0 0.8 1.4 0.6 1.3 38.7 265.1 3.6 0.0 1.0 2.3 11.2 0.6 0.6 0.0 19.7 0.0 14.3 1.0 95.5 30.2 0.1 0.1 0.7 8.4 1.6 1.1 0.7 7.0 32.7 0.0 2.2 1.5 5.1 2.6 0.6 4.4 0.1 0.8 0.9 0.4 2.3 ENO4 "AC023283.3, C10orf134" ENSG00000188316 "Enolase 4" A6NNW6 10 116849499-116911788 "Enzymes, Predicted intracellular proteins" Glycolysis Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 11.5;choroid plexus: 4.7;fallopian tube: 5.0" "Cell type enhanced" "Detected in some" "Astrocytes: 16.3;Cone photoreceptor cells: 22.9;Early spermatids: 15.5;Endometrial ciliated cells: 15.8;Inhibitory neurons: 18.4;Late spermatids: 15.8;Oligodendrocytes: 62.4;Respiratory ciliated cells: 30.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA037937, HPA037938" Enhanced Approved Nucleoplasm,Mitochondria NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 49: Ciliated cells - Cilium organization" Mitochondria Nucleoplasm "HPA037937: AB_10697089, HPA037938: AB_2675746" "unprognostic (2.92e-3)" "unprognostic (1.39e-1)" "unprognostic (1.07e-1)" "unprognostic (6.55e-4)" "unprognostic (8.38e-5)" "unprognostic (1.88e-1)" "unprognostic (2.21e-1)" "unprognostic (5.18e-2)" "unprognostic (1.22e-1)" "unprognostic (2.23e-2)" "unprognostic (3.74e-3)" "unprognostic (2.06e-1)" "unprognostic (2.20e-3)" "unprognostic (1.18e-1)" "unprognostic (9.77e-3)" "unprognostic (9.87e-5)" "unprognostic (1.08e-2)" 0.2 0.3 1.7 0.0 5.3 0.0 0.4 1.7 3.4 0.4 4.7 0.3 0.0 0.6 1.3 0.1 5.0 0.3 0.1 2.1 2.6 0.6 1.3 0.6 0.1 4.8 4.5 0.5 0.6 1.0 1.0 0.0 3.5 0.3 0.1 2.0 0.2 0.4 0.0 0.2 0.2 0.2 2.6 0.2 0.3 2.5 4.0 0.1 0.7 0.0 0.0 0.1 0.2 11.5 0.3 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.2 0.0 0.0 0.2 0.8 0.0 0.2 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 5.3 1.7 3.4 2.1 2.6 4.8 4.5 3.5 2.6 4.0 11.5 0.0 0.0 0.0 16.3 0.0 0.1 0.3 0.8 0.6 4.9 0.4 0.3 0.3 0.0 0.4 0.0 22.9 0.3 0.0 0.2 0.0 0.5 15.5 15.8 0.7 0.1 1.8 0.0 12.2 0.2 0.2 0.7 0.0 1.1 0.0 0.5 0.0 0.0 0.0 5.0 18.4 0.0 0.0 0.0 0.6 15.8 1.2 0.2 0.0 8.4 0.6 1.3 0.0 4.5 62.4 0.2 0.1 0.7 0.0 0.1 0.3 0.8 30.2 8.4 0.0 1.0 0.5 9.4 2.9 0.1 0.0 0.1 0.0 1.0 0.3 0.1 ENY2 "DC6, FLJ20480, Sus1" ENSG00000120533 "ENY2 transcription and export complex 2 subunit" Q9NPA8 8 109334324-109345954 "Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Transcription, Transcription regulation, Translocation, Transport" "Activator, Chromatin regulator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024648 Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Mitochondria" "HPA024648: AB_2100208" "unprognostic (2.10e-3)" "unprognostic (1.96e-1)" "unprognostic (2.18e-1)" "unprognostic (7.85e-2)" "unprognostic (7.70e-2)" "unprognostic (7.45e-3)" "unprognostic (1.48e-2)" "unprognostic (6.65e-2)" "unprognostic (2.54e-1)" "unprognostic (1.21e-2)" "unprognostic (1.47e-1)" "unprognostic (8.86e-3)" "prognostic unfavorable (7.17e-6)" "unprognostic (1.74e-1)" "unprognostic (1.51e-1)" "unprognostic (8.84e-2)" "unprognostic (2.66e-1)" 54.4 55.5 28.1 44.7 29.1 87.6 57.0 29.3 45.3 44.2 32.9 59.5 54.5 37.9 53.8 48.2 36.1 29.9 64.2 29.1 32.2 74.4 101.3 40.4 49.6 31.5 30.5 29.5 44.9 47.2 34.4 41.3 30.1 39.0 55.1 24.5 43.7 36.0 71.7 34.7 47.9 44.1 29.8 47.7 47.9 34.8 29.7 60.3 38.0 68.5 53.8 48.4 38.9 30.9 180.3 145.9 213.6 97.1 79.5 101.0 61.4 140.0 89.9 141.2 177.2 109.0 109.1 115.3 127.9 110.9 63.6 89.7 96.8 99.5 171.7 184.1 113.9 223.5 106.7 227.4 85.4 78.3 133.5 77.5 66.7 92.5 87.3 102.2 215.1 111.5 216.5 63.7 162.7 289.9 235.9 175.5 156.1 207.1 140.3 148.4 93.2 144.5 192.5 134.7 128.9 137.5 87.7 109.3 127.2 117.0 138.6 132.3 146.9 94.1 158.9 97.8 144.7 107.9 125.6 222.2 95.2 128.3 112.7 65.6 102.5 93.5 28.9 112.8 36.7 41.4 39.0 35.6 93.8 27.3 31.9 35.8 56.8 42.4 121.8 80.3 42.3 74.5 28.1 29.1 29.3 45.3 29.1 32.2 31.5 30.5 30.1 29.8 29.7 30.9 231.3 70.5 93.8 16.3 135.0 185.6 196.3 305.7 159.9 63.8 149.2 192.7 170.6 138.7 184.6 145.3 123.0 263.3 157.0 171.5 381.5 214.3 173.3 146.4 134.7 226.3 154.2 160.1 22.7 200.0 284.5 161.0 88.7 144.8 91.8 99.3 142.5 371.1 276.8 45.4 23.9 245.1 225.9 230.3 265.7 111.0 148.2 205.0 158.3 17.8 260.9 112.4 126.7 19.6 27.6 251.2 237.1 112.5 147.2 230.3 264.5 546.1 125.0 139.9 78.9 163.9 262.9 208.7 130.4 151.0 174.6 167.3 132.4 143.9 209.1 208.0 EXOC3 "SEC6L1, Sec6p" ENSG00000180104 "Exocyst complex component 3" O60645 5 443175-471937 "Predicted intracellular proteins, Transporters" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 61.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037880 Approved Nucleoplasm,Mitochondria NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 20: HeLa - Mitochondria" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Mitochondria" "HPA037880: AB_2675716" "unprognostic (2.94e-1)" "unprognostic (4.74e-3)" "unprognostic (4.82e-3)" "unprognostic (4.10e-1)" "unprognostic (6.18e-2)" "unprognostic (1.10e-2)" "unprognostic (2.91e-3)" "unprognostic (1.91e-1)" "unprognostic (6.62e-2)" "unprognostic (3.26e-1)" "prognostic favorable (1.54e-4)" "unprognostic (6.54e-2)" "unprognostic (2.33e-1)" "unprognostic (5.02e-2)" "unprognostic (2.97e-1)" "unprognostic (1.82e-1)" "unprognostic (1.70e-1)" 27.1 22.0 16.7 20.3 19.1 24.3 25.5 20.9 18.7 27.0 18.5 38.1 20.8 29.1 10.7 36.4 25.6 19.3 28.6 19.0 19.0 22.7 21.8 22.3 23.6 18.5 18.4 26.1 31.7 22.1 26.0 18.5 19.8 24.6 14.4 8.0 26.7 20.3 78.8 34.4 27.0 19.0 16.6 26.5 32.9 35.6 18.2 22.9 25.0 41.2 20.1 31.4 27.6 20.3 33.5 55.3 18.2 40.9 30.6 26.3 45.2 29.1 29.9 28.6 34.5 28.0 48.0 28.4 44.2 36.6 35.3 37.2 14.7 25.2 20.9 105.8 25.7 30.6 114.0 21.3 28.6 46.0 73.9 26.8 18.4 32.1 28.0 30.0 32.5 18.3 23.6 18.1 22.5 39.7 33.2 54.8 15.1 20.5 33.0 27.0 20.9 36.5 24.1 41.4 18.2 23.2 72.5 40.5 28.8 17.7 54.8 52.5 24.5 28.3 34.6 22.0 23.8 30.3 23.6 20.2 29.8 55.1 26.2 10.4 10.5 61.0 11.2 12.4 9.8 6.0 8.8 9.1 6.6 6.4 11.1 10.2 14.8 19.4 9.1 4.8 12.4 7.1 16.7 19.1 20.9 18.7 19.0 19.0 18.5 18.4 19.8 16.6 18.2 20.3 15.5 22.4 29.1 15.0 14.1 42.8 16.3 18.6 20.5 14.0 18.1 16.5 31.4 14.3 21.1 14.7 35.5 25.3 15.6 28.9 27.4 27.3 31.8 16.4 16.2 17.1 5.4 14.7 12.6 30.2 24.2 16.6 23.4 17.0 22.9 27.7 13.9 16.9 24.0 63.9 11.2 20.3 18.3 26.9 23.8 65.3 20.2 24.6 26.6 10.3 25.2 17.0 13.4 10.6 16.7 26.4 23.1 17.0 18.6 18.0 25.5 23.1 29.3 20.2 19.7 19.1 24.8 33.9 29.7 29.4 53.8 34.1 22.7 21.1 23.5 24.6 F7 ENSG00000057593 "Coagulation factor VII" P08709 13 113105788-113120685 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 102 "liver: 160.2" "Cell type enriched" "Detected in some" 18 "Hepatocytes: 149.3" "Cancer enriched" "Detected in some" 17 "liver cancer: 41.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "CACO-2: 11.5;Hep G2: 7.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA004826 Approved Mitochondria "Secreted to blood" NA NA 351000000 1300000000 "Cluster 62: Liver - Hemostasis" "Cluster 39: CACO-2 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" Mitochondria "HPA004826: AB_10602805" "unprognostic (2.06e-1)" "unprognostic (2.55e-1)" "unprognostic (1.03e-1)" "unprognostic (1.34e-1)" "unprognostic (3.27e-1)" "unprognostic (1.91e-1)" "unprognostic (1.50e-3)" "unprognostic (3.81e-1)" "unprognostic (4.36e-3)" "unprognostic (1.16e-1)" "unprognostic (4.19e-3)" "unprognostic (1.15e-1)" "unprognostic (1.35e-3)" "unprognostic (3.36e-3)" "unprognostic (1.09e-1)" "unprognostic (2.86e-1)" "unprognostic (1.47e-1)" 0.2 0.0 0.4 0.1 0.3 0.0 0.2 0.5 0.7 1.1 0.2 0.1 0.5 0.1 0.6 0.1 0.5 0.0 0.2 0.3 0.7 0.4 160.2 0.1 0.0 0.3 0.5 0.4 0.1 0.2 0.4 0.1 0.3 0.4 0.0 0.2 0.3 0.0 0.0 0.4 0.8 0.0 0.2 0.1 0.1 1.5 0.6 0.0 0.1 0.0 0.0 0.1 0.5 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 11.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.5 0.7 0.3 0.7 0.3 0.5 0.3 0.2 0.6 0.3 0.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.6 0.3 0.5 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.4 0.0 8.0 0.3 0.2 0.0 0.4 0.0 0.2 0.0 0.3 2.2 149.3 0.1 0.0 0.5 0.4 0.0 2.8 0.7 0.2 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.0 1.1 0.3 0.0 0.2 0.0 0.5 0.1 3.2 4.1 0.0 0.1 0.1 0.2 0.1 0.3 0.0 FAM136A FLJ14668 ENSG00000035141 "Family with sequence similarity 136 member A" Q96C01 2 70295975-70302090 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030103, HPA030104" Enhanced Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 55: Plasma cells - Humoral immune response" Mitochondria "HPA030103: AB_10600194, HPA030104: AB_10600534" "unprognostic (2.81e-1)" "unprognostic (5.76e-2)" "unprognostic (9.16e-2)" "unprognostic (3.69e-2)" "unprognostic (5.53e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (2.66e-4)" "unprognostic (1.14e-1)" "unprognostic (1.12e-2)" "unprognostic (1.28e-2)" "unprognostic (5.91e-2)" "unprognostic (2.09e-1)" "prognostic unfavorable (1.33e-6)" "unprognostic (4.95e-3)" "unprognostic (3.03e-1)" "unprognostic (4.03e-1)" "unprognostic (2.00e-3)" 10.7 12.2 16.0 17.8 16.4 20.4 16.8 16.4 19.4 15.2 16.1 25.9 26.1 10.0 14.6 19.2 14.3 9.7 21.5 16.0 17.8 20.1 32.5 10.5 17.5 17.0 17.0 10.6 31.4 20.6 10.3 18.0 17.9 15.8 27.1 16.4 27.1 14.1 24.5 14.7 21.6 14.0 15.8 13.6 19.6 8.9 17.9 17.7 20.6 22.2 21.4 17.8 10.5 15.5 94.8 83.4 51.5 72.4 26.5 39.1 78.4 50.2 47.7 67.8 46.8 222.0 53.3 64.9 44.5 43.6 58.9 42.5 106.8 40.0 69.2 67.1 121.3 99.7 62.1 138.8 38.1 166.5 62.7 27.0 27.3 63.9 54.0 36.3 73.8 93.0 161.1 51.0 51.0 138.0 107.6 143.9 129.2 127.7 88.7 71.2 96.2 107.1 104.9 65.4 119.7 52.3 37.7 90.6 76.1 47.3 37.6 47.9 44.9 28.9 85.1 44.7 96.2 42.3 70.0 75.2 72.0 93.2 50.1 35.8 27.9 21.0 21.3 39.8 31.9 37.0 23.6 25.9 37.8 33.2 27.3 27.6 2.6 53.4 27.9 24.8 20.5 29.6 16.0 16.4 16.4 19.4 16.0 17.8 17.0 17.0 17.9 15.8 17.9 15.5 16.7 41.7 31.6 8.8 49.5 28.0 35.4 41.3 35.3 26.3 46.6 46.1 54.7 11.5 38.9 33.1 25.0 89.5 46.0 52.3 70.5 71.8 1.3 39.3 28.3 20.1 32.9 50.5 8.6 99.1 107.5 31.9 40.8 47.1 27.9 46.1 18.9 59.3 69.8 8.4 9.4 61.2 44.7 22.4 29.2 3.6 13.4 31.9 28.4 3.7 42.0 29.1 49.4 6.0 3.6 95.0 58.1 18.4 88.6 54.8 69.7 73.5 31.8 26.7 13.1 19.8 32.5 14.0 53.8 49.8 41.9 29.6 36.8 49.2 66.7 45.7 FAM160A2 "C11orf56, DKFZP566M1046, FHIP, FLJ22665, KIAA1759" ENSG00000051009 "Family with sequence similarity 160 member A2" Q8N612 11 6211345-6234711 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 76.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055994, HPA063987" Approved Approved Mitochondria NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA055994: AB_2682999, HPA063987: AB_2685166" "unprognostic (1.40e-1)" "unprognostic (1.58e-1)" "unprognostic (3.44e-2)" "unprognostic (9.59e-3)" "unprognostic (2.20e-2)" "unprognostic (1.51e-1)" "unprognostic (4.16e-2)" "unprognostic (2.64e-1)" "unprognostic (2.19e-1)" "unprognostic (5.02e-2)" "unprognostic (2.16e-1)" "unprognostic (8.04e-2)" "unprognostic (6.65e-2)" "unprognostic (1.93e-1)" "unprognostic (1.64e-1)" "unprognostic (9.58e-2)" "unprognostic (1.85e-1)" 16.5 14.5 6.2 14.2 6.5 42.3 18.1 6.8 7.2 20.1 9.5 29.8 34.1 21.6 9.5 13.2 20.2 17.8 12.4 6.4 3.8 13.8 20.8 16.0 13.3 4.0 4.4 21.3 24.7 16.3 14.9 12.1 3.5 15.7 27.7 9.6 18.6 14.7 14.0 23.5 33.8 15.8 2.9 14.2 18.9 27.2 4.4 11.3 22.7 10.5 8.9 16.5 16.5 4.4 13.5 13.1 9.0 13.4 11.9 12.8 19.5 7.6 9.1 11.1 10.6 11.2 24.4 10.5 8.2 8.9 18.3 17.4 9.2 13.8 6.7 11.6 13.1 3.6 24.1 6.0 9.8 8.9 11.6 11.7 17.0 10.0 17.7 14.5 11.4 16.2 11.5 12.7 7.0 10.7 8.5 17.0 13.4 17.5 12.2 9.3 4.7 8.6 10.4 9.6 12.0 7.9 10.9 12.7 6.9 9.3 8.7 12.4 9.8 13.6 10.4 20.4 8.1 17.0 15.7 8.1 15.0 7.0 12.3 1.3 3.1 3.4 3.0 1.3 1.8 1.3 1.2 2.2 2.0 1.3 0.9 1.6 3.3 1.1 1.0 0.6 0.2 2.0 6.2 6.5 6.8 7.2 6.4 3.8 4.0 4.4 3.5 2.9 4.4 4.4 19.0 19.2 16.2 28.1 10.1 12.5 11.1 12.5 10.8 12.6 17.8 12.3 4.5 14.3 12.2 12.9 16.7 13.5 15.9 76.8 7.9 11.4 24.2 15.6 10.1 15.2 25.0 18.5 21.3 11.3 10.1 12.9 33.6 11.2 7.0 27.6 9.3 23.7 9.6 6.7 15.8 37.9 16.2 17.6 28.5 6.5 9.9 12.3 14.2 11.2 16.9 7.6 37.0 14.1 15.6 17.6 47.8 7.5 8.3 10.8 65.0 8.8 18.6 24.4 13.1 10.6 11.6 38.5 21.7 8.5 14.9 11.5 14.7 21.9 39.5 10.4 FAM167A "C8orf13, DIORA-1" ENSG00000154319 "Family with sequence similarity 167 member A" Q96KS9 8 11421476-11475908 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.1;thyroid gland: 53.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 16.0;Astrocytes: 28.4;Distal tubular cells: 13.7;Early spermatids: 24.8;Enteroendocrine cells: 19.1;Late spermatids: 41.1" "Cancer enhanced" "Detected in many" "thyroid cancer: 16.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Daudi: 57.6;RPMI-8226: 61.5;SH-SY5Y: 44.4;U-698: 44.8;U-87 MG: 36.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023915, HPA030426" Approved Approved Mitochondria NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 68: Epididymis - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Mitochondria "HPA023915: AB_1845768, HPA030426: AB_10601318" "unprognostic (8.51e-3)" "unprognostic (2.43e-1)" "unprognostic (1.25e-3)" "prognostic unfavorable (5.96e-4)" "unprognostic (3.08e-2)" "unprognostic (4.62e-3)" "unprognostic (1.79e-1)" "unprognostic (1.45e-1)" "unprognostic (1.51e-1)" "unprognostic (1.39e-1)" "unprognostic (4.06e-2)" "unprognostic (7.17e-2)" "unprognostic (1.77e-2)" "unprognostic (7.13e-2)" "unprognostic (1.56e-1)" "unprognostic (4.30e-2)" "unprognostic (2.21e-2)" 0.6 0.8 25.8 1.2 25.1 0.7 1.3 23.9 25.3 0.8 17.0 0.7 0.3 0.1 0.5 0.9 1.3 1.0 0.2 26.6 26.7 6.4 0.3 10.2 2.4 29.8 27.6 0.0 2.1 1.7 17.4 0.9 27.9 1.5 0.7 5.2 2.6 4.6 0.0 11.8 1.3 0.0 26.6 1.2 2.0 3.8 31.1 3.0 53.2 0.1 3.0 0.3 1.6 25.1 4.8 3.0 6.1 0.6 0.4 2.5 0.2 16.8 16.0 10.1 4.4 0.2 1.5 57.6 0.9 18.3 4.7 1.6 0.1 4.0 11.9 24.8 0.8 0.0 0.1 0.0 20.8 0.0 0.1 2.9 2.6 5.3 32.2 32.3 0.0 0.0 0.2 2.2 6.0 1.8 0.1 0.0 1.6 0.1 0.1 0.3 0.0 61.5 5.1 0.5 26.3 44.4 0.8 4.7 2.2 0.8 1.8 0.1 28.5 1.0 1.6 25.8 0.2 17.7 14.0 44.8 36.3 0.1 1.6 0.0 0.0 0.0 0.0 0.5 0.0 1.2 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.3 0.5 0.4 0.0 0.0 25.8 25.1 23.9 25.3 26.6 26.7 29.8 27.6 27.9 26.6 31.1 25.1 0.0 16.0 1.8 28.4 5.4 5.9 0.6 0.5 0.0 0.1 1.2 1.3 0.7 1.5 0.5 5.5 10.4 0.0 1.1 0.2 13.7 2.1 24.8 2.1 0.2 0.2 19.1 0.0 0.6 1.8 0.0 0.3 2.6 0.9 0.0 0.0 0.0 0.0 0.1 0.0 1.4 1.3 0.0 0.3 0.3 41.1 0.3 0.3 0.0 3.7 0.3 1.7 0.0 0.0 1.3 1.1 2.4 0.4 0.9 0.8 0.1 0.2 1.9 1.8 0.0 0.3 0.2 3.9 2.2 0.0 3.4 0.0 1.0 0.1 0.1 0.2 FAM171B "FLJ34104, KIAA1946" ENSG00000144369 "Family with sequence similarity 171 member B" Q6P995 2 186694060-186765959 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 54.8" "Group enriched" "Detected in many" 5 "Astrocytes: 258.6;Bipolar cells: 141.4;Excitatory neurons: 126.5;Inhibitory neurons: 114.2;Oligodendrocyte precursor cells: 102.1;Oligodendrocytes: 78.5" "Cancer enriched" "Detected in many" 5 "glioma: 15.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Karpas-707: 43.7;U-138 MG: 29.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010639, HPA013434" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 58: Brain - Synaptic function" "Cluster 2: Karpas-707 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Mitochondria" "HPA010639: AB_1852447, HPA013434: AB_2262499" "unprognostic (2.52e-1)" "unprognostic (7.75e-3)" "unprognostic (1.27e-1)" "unprognostic (1.04e-2)" "unprognostic (4.03e-2)" "unprognostic (9.43e-2)" "unprognostic (6.78e-3)" "unprognostic (2.68e-1)" "unprognostic (1.88e-2)" "unprognostic (1.52e-1)" "unprognostic (4.24e-3)" "unprognostic (1.47e-1)" "prognostic unfavorable (9.51e-7)" "unprognostic (4.63e-3)" "unprognostic (1.52e-1)" "unprognostic (2.24e-3)" "prognostic unfavorable (5.03e-4)" 2.9 14.4 36.1 1.5 52.2 0.5 3.4 8.3 54.8 6.6 0.0 1.8 1.0 7.5 2.1 1.9 2.7 4.9 1.4 52.8 33.0 1.2 0.3 1.4 1.2 15.0 16.9 10.2 1.0 7.6 10.7 3.3 17.6 2.7 2.0 24.1 23.0 2.3 0.7 3.7 1.4 4.4 17.2 1.5 2.0 0.9 28.3 2.8 2.2 3.6 1.1 2.2 2.2 30.1 4.2 4.9 7.2 22.6 20.9 15.7 0.1 4.5 8.0 5.5 7.8 13.6 21.9 0.0 1.6 12.9 9.3 0.5 9.9 4.3 7.8 0.0 5.7 5.1 2.1 0.0 1.6 1.5 1.7 20.2 1.8 4.2 3.4 7.1 12.1 3.9 0.0 43.7 10.5 2.9 3.0 0.0 9.6 0.0 4.9 0.0 13.9 1.0 8.5 15.8 22.4 12.2 2.3 1.4 6.1 4.2 1.7 1.0 7.1 29.7 3.9 0.5 2.9 11.5 12.0 0.0 9.2 0.0 4.2 0.2 0.1 0.0 0.1 0.3 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.4 0.2 0.2 0.0 0.0 36.1 52.2 8.3 54.8 52.8 33.0 15.0 16.9 17.6 17.2 28.3 30.1 9.1 0.0 0.0 258.6 0.1 8.9 2.8 1.2 4.0 141.4 10.7 5.7 0.8 5.7 5.7 0.0 14.6 11.4 0.5 0.0 0.0 1.0 1.3 1.5 13.0 14.4 4.8 1.3 126.5 0.4 0.8 14.1 2.6 4.7 0.0 0.8 6.8 0.1 2.0 23.5 114.2 0.0 4.1 0.3 2.8 4.0 7.8 1.0 3.6 18.7 0.7 16.2 0.0 102.1 78.5 0.7 0.0 13.9 0.2 1.4 0.0 0.2 2.6 17.0 0.0 8.6 4.5 0.4 1.5 0.6 5.3 8.2 0.9 2.6 0.0 1.1 FAM181B "LOC220382, MGC33846" ENSG00000182103 "Family with sequence similarity 181 member B" A6NEQ2 11 82729940-82733864 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 26.9" "Cell type enhanced" "Detected in some" "Astrocytes: 56.2;Endometrial ciliated cells: 24.1;Muller glia cells: 18.4;Oligodendrocyte precursor cells: 22.1;Oligodendrocytes: 19.0" "Cancer enriched" "Detected in many" 19 "glioma: 29.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RT4: 2.4;SH-SY5Y: 1.2;U-2 OS: 1.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066861 Enhanced Approved "Nuclear membrane,Mitochondria" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 15: RT4 - Unknown function" "Cluster 64: Astrocytes - Nervous system maintenance" Mitochondria "Nuclear membrane" "HPA066861: AB_2685738" "unprognostic (2.84e-4)" "unprognostic (3.47e-2)" "unprognostic (1.80e-1)" "prognostic favorable (8.07e-4)" "unprognostic (6.71e-3)" "unprognostic (3.18e-2)" "unprognostic (1.15e-1)" "unprognostic (6.48e-2)" "unprognostic (1.90e-1)" "unprognostic (5.50e-2)" "unprognostic (6.27e-4)" "unprognostic (2.52e-3)" "unprognostic (6.81e-2)" "unprognostic (1.53e-2)" "unprognostic (2.56e-1)" "unprognostic (7.20e-3)" "unprognostic (7.20e-2)" 0.5 0.6 18.0 0.2 20.3 0.1 0.4 19.8 14.3 1.3 5.9 1.4 0.2 0.7 0.1 0.3 1.0 0.0 1.7 14.5 14.7 0.7 0.0 0.0 0.0 26.9 20.8 0.8 0.5 0.1 1.2 0.0 16.3 0.6 0.0 0.6 0.8 0.5 0.2 0.3 0.4 0.1 23.9 0.0 0.4 0.2 19.9 0.0 0.8 0.1 0.2 1.1 0.7 23.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 2.4 0.3 1.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.0 20.3 19.8 14.3 14.5 14.7 26.9 20.8 16.3 23.9 19.9 23.6 0.7 0.0 0.0 56.2 0.0 0.3 0.2 0.1 0.0 0.8 1.0 3.6 2.9 0.0 0.1 5.5 0.0 0.0 0.0 0.0 3.9 0.1 0.0 24.1 1.8 1.3 0.0 0.0 0.4 0.0 0.0 1.2 0.0 2.4 0.0 0.6 0.0 0.0 0.1 0.0 0.6 1.5 0.0 0.0 0.3 0.4 0.6 0.2 1.8 1.9 0.0 18.4 0.0 22.1 19.0 0.0 0.0 0.4 0.0 0.2 0.1 0.4 0.1 1.1 0.0 1.6 7.0 0.1 1.6 0.3 0.0 0.0 0.1 2.2 0.2 0.1 FAM210A "C18orf19, HsT2329, MGC24180" ENSG00000177150 "Family with sequence similarity 210 member A" Q96ND0 18 13663347-13726663 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 33.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014324, HPA051564" Uncertain Approved "Nucleoplasm,Golgi apparatus,Mitochondria" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Golgi apparatus, Mitochondria" "HPA014324: AB_2668972, HPA051564: AB_2681536" "unprognostic (1.32e-1)" "unprognostic (6.98e-2)" "unprognostic (5.78e-2)" "unprognostic (9.18e-3)" "unprognostic (4.13e-2)" "prognostic unfavorable (8.14e-4)" "unprognostic (2.23e-3)" "unprognostic (1.11e-2)" "unprognostic (2.26e-1)" "unprognostic (5.53e-3)" "unprognostic (6.79e-3)" "unprognostic (2.98e-2)" "unprognostic (3.27e-3)" "unprognostic (7.67e-2)" "unprognostic (2.86e-1)" "unprognostic (1.78e-1)" "unprognostic (4.82e-2)" 6.1 4.7 4.7 5.5 4.5 3.5 4.8 5.8 7.1 4.2 8.0 6.9 9.3 3.9 2.9 8.8 4.2 4.0 21.8 4.6 5.3 9.4 13.2 4.0 6.4 5.2 7.0 5.6 3.3 6.4 2.6 7.5 5.6 4.4 6.4 11.5 5.1 4.6 25.5 3.3 6.2 6.2 5.1 3.7 4.7 8.4 6.3 5.3 6.3 33.1 7.3 6.3 5.0 5.7 24.6 13.6 9.4 8.8 10.9 11.2 13.6 16.5 15.3 18.2 21.1 18.4 11.6 24.9 20.2 11.8 33.6 11.5 18.2 20.6 29.5 17.4 8.4 17.7 9.7 13.0 12.9 30.3 15.9 9.7 15.9 17.5 61.6 12.7 11.9 14.8 24.2 13.4 21.2 16.8 18.7 19.5 10.6 47.7 13.5 15.2 22.3 29.1 15.1 15.3 6.0 10.1 14.5 21.1 40.0 13.4 10.8 14.2 13.2 46.4 45.7 29.1 20.6 15.1 20.1 28.8 24.6 15.6 18.9 3.5 5.3 3.3 6.2 8.0 6.8 5.7 5.2 5.4 6.4 6.3 6.4 6.2 0.8 6.0 4.2 4.0 5.4 3.8 4.7 4.5 5.8 7.1 4.6 5.3 5.2 7.0 5.6 5.1 6.3 5.7 14.9 9.6 8.3 13.7 29.8 55.3 14.8 28.3 12.5 63.2 11.0 11.2 66.4 12.8 14.6 7.3 20.9 20.6 11.6 9.1 21.5 18.6 20.5 16.7 21.6 18.3 11.4 5.9 18.0 8.8 39.0 17.4 10.2 32.7 7.0 36.7 6.8 20.7 20.0 30.3 23.5 10.0 10.2 9.5 43.4 6.1 9.3 26.5 8.8 15.0 11.4 19.0 15.5 18.6 24.8 12.6 4.1 10.1 14.2 19.9 12.1 29.8 5.0 29.9 6.6 16.3 15.4 31.4 32.3 20.6 57.3 25.7 16.8 45.6 20.5 14.8 FAM83F ENSG00000133477 "Family with sequence similarity 83 member F" Q8NEG4 22 39994954-40043534 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 20.3;testis: 40.8" "Cell type enhanced" "Detected in many" "Late spermatids: 68.1;Proximal enterocytes: 39.9;Suprabasal keratinocytes: 34.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 12.1;HaCaT: 12.8;HBEC3-KT: 15.5;hTCEpi: 37.9;hTERT-HME1: 11.8;OE19: 17.6;RT4: 18.6;SCLC-21H: 39.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA051207, HPA064657" Enhanced Approved Nucleoplasm,Mitochondria NA NA "Cluster 10: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria Nucleoplasm "HPA051207: AB_2681388, HPA064657: AB_2685313" "unprognostic (2.78e-2)" "unprognostic (3.91e-2)" "prognostic favorable (1.73e-4)" "unprognostic (5.36e-2)" "unprognostic (1.48e-5)" "unprognostic (1.39e-2)" "unprognostic (1.75e-1)" "unprognostic (4.75e-2)" "unprognostic (4.79e-1)" "unprognostic (2.48e-1)" "prognostic favorable (9.40e-4)" "unprognostic (3.25e-1)" "unprognostic (1.10e-7)" "unprognostic (2.93e-1)" "unprognostic (2.37e-1)" "unprognostic (2.98e-2)" "unprognostic (8.32e-2)" 1.2 0.1 0.2 0.5 0.1 1.2 4.7 0.3 0.2 2.6 0.1 5.3 3.2 0.2 2.5 20.3 1.2 0.5 2.0 0.2 0.1 4.0 2.9 0.2 0.0 0.1 0.1 0.3 13.5 5.4 1.2 0.1 0.1 9.0 3.2 0.4 8.2 6.6 0.1 18.8 7.6 0.1 0.0 0.0 6.8 40.8 0.3 0.9 5.9 0.2 1.1 2.6 7.0 0.3 8.3 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 12.1 2.3 0.0 0.0 0.0 0.0 12.8 0.0 15.5 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 37.9 0.0 11.8 0.0 0.0 2.0 0.0 0.1 0.0 0.0 0.0 0.1 2.1 17.6 0.0 0.0 0.0 0.1 0.3 18.6 39.8 0.0 0.3 3.4 0.0 1.3 2.3 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.3 0.2 0.2 0.1 0.1 0.1 0.1 0.0 0.3 0.3 1.1 0.0 0.0 0.0 0.5 28.7 14.5 18.0 23.9 1.2 19.1 10.4 5.2 12.8 7.4 23.9 0.0 0.2 0.0 33.1 3.9 9.6 28.4 6.2 0.5 1.0 13.1 0.4 0.2 15.1 0.2 1.0 10.7 6.5 1.3 0.2 0.0 2.2 0.2 0.0 0.2 21.0 14.2 0.6 2.9 68.1 1.8 0.5 1.8 0.0 0.0 0.9 0.0 0.5 0.1 12.5 21.6 2.2 0.2 16.3 39.9 5.9 6.4 0.6 0.0 1.1 1.3 12.4 1.8 30.6 34.5 1.4 0.8 0.4 15.6 17.8 FBP1 FBP ENSG00000165140 "Fructose-bisphosphatase 1" P09467 9 94603133-94640249 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Gluconeogenesis" "Allosteric enzyme, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 324.4;kidney: 297.8;liver: 893.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 500.4;Macrophages: 238.6;Proximal enterocytes: 1095.0;Proximal tubular cells: 864.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 404.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HaCaT: 75.2;MCF7: 243.4;OE19: 54.5;RT4: 157.0;U-698: 170.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA005857, HPA012513, CAB033869" Enhanced Approved Mitochondria NA NA 21000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "CAB033869: AB_1121520, HPA005857: AB_1848445, HPA012513: AB_1848446" "unprognostic (4.95e-2)" "unprognostic (1.40e-2)" "unprognostic (1.40e-1)" "prognostic favorable (5.16e-4)" "unprognostic (1.13e-2)" "unprognostic (1.37e-1)" "prognostic favorable (1.79e-4)" "unprognostic (6.94e-3)" "unprognostic (4.52e-2)" "unprognostic (7.79e-2)" "unprognostic (7.59e-2)" "unprognostic (1.12e-1)" "prognostic favorable (6.86e-7)" "unprognostic (6.91e-2)" "unprognostic (3.22e-2)" "unprognostic (1.07e-1)" "prognostic favorable (1.64e-5)" 13.7 27.4 1.6 12.7 1.8 15.0 41.4 1.8 5.7 19.9 2.6 29.8 324.4 3.6 15.8 2.7 7.1 34.4 2.9 1.5 2.2 297.8 893.2 165.9 6.8 3.6 2.6 1.1 41.4 107.9 8.6 3.0 2.9 25.8 30.5 0.7 53.2 28.9 1.3 8.1 258.1 8.8 2.6 12.2 85.6 2.5 3.2 2.2 16.8 0.9 7.8 70.8 6.7 3.8 0.5 0.1 0.3 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.1 0.6 3.8 0.0 0.3 0.8 0.1 75.2 0.1 0.0 0.1 0.0 0.3 0.6 2.9 1.3 0.0 1.5 18.8 0.0 0.1 0.0 0.0 0.0 2.0 0.0 0.2 0.3 0.2 243.4 0.1 4.4 1.1 54.5 9.5 0.0 0.9 1.9 0.0 157.0 0.7 5.6 0.6 44.5 0.0 0.9 26.7 7.7 0.2 0.1 1.0 0.8 0.0 0.3 1.1 170.4 0.0 1.4 0.1 63.3 68.4 404.3 7.9 162.3 11.7 3.0 4.6 4.6 90.1 3.2 16.2 8.3 12.1 15.4 90.7 32.1 2.3 33.1 1.6 1.8 1.8 5.7 1.5 2.2 3.6 2.6 2.9 2.6 3.2 3.8 2.8 76.9 182.8 0.0 10.3 0.8 8.9 0.7 0.0 0.1 62.4 24.3 0.7 102.9 41.0 62.5 0.0 11.1 14.8 26.1 111.6 21.5 0.1 4.0 0.4 4.8 31.9 24.4 0.9 62.7 1.7 5.4 102.4 5.2 47.4 16.0 12.1 500.4 177.6 0.0 0.8 61.4 0.0 79.9 32.1 1.5 1.5 238.6 12.4 1.9 20.1 2.6 8.2 0.5 0.3 24.0 77.6 4.1 18.3 11.9 1095.0 864.1 9.1 0.2 6.6 0.6 2.0 0.6 1.3 0.8 1.0 10.1 12.1 0.5 90.4 68.1 FBXL12 "Fbl12, FLJ20188" ENSG00000127452 "F-box and leucine rich repeat protein 12" Q9NXK8 19 9810267-9827816 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 63.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002843 Approved Approved Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 50: Non-specific - Ribosome" "Cluster 24: NB-4 - Immune response" "Cluster 33: Fibroblasts - ECM organization" Mitochondria "HPA002843: AB_2666679" "unprognostic (7.65e-2)" "unprognostic (5.88e-2)" "unprognostic (7.72e-2)" "unprognostic (3.82e-2)" "unprognostic (8.21e-2)" "prognostic favorable (3.21e-4)" "prognostic unfavorable (1.41e-4)" "unprognostic (6.45e-2)" "prognostic unfavorable (4.96e-4)" "unprognostic (1.38e-3)" "unprognostic (1.49e-2)" "unprognostic (4.07e-3)" "unprognostic (9.28e-3)" "unprognostic (1.41e-1)" "unprognostic (1.36e-1)" "unprognostic (2.61e-1)" "unprognostic (4.77e-3)" 20.0 15.0 8.9 10.4 9.6 27.1 19.1 12.0 10.4 21.5 9.5 22.5 14.9 23.5 10.8 17.2 22.6 9.0 17.0 8.7 9.0 19.4 22.4 17.3 12.8 10.5 8.8 23.9 14.6 7.1 17.5 15.1 10.2 19.5 10.5 6.4 13.5 10.7 19.0 16.6 21.0 11.1 8.0 18.2 17.3 13.2 9.9 44.0 17.6 9.4 8.9 23.6 18.2 10.9 18.8 9.3 21.1 20.6 23.5 20.8 24.1 19.9 20.1 21.2 24.9 28.9 12.1 17.5 31.2 20.1 16.4 17.7 16.0 17.6 16.8 17.7 30.9 33.9 21.1 28.8 30.2 24.8 20.1 29.9 11.5 20.4 18.0 15.6 15.1 44.6 26.2 35.6 11.2 14.9 36.3 76.3 24.3 11.4 17.2 21.5 15.7 31.7 15.3 25.2 13.1 17.9 14.7 10.8 23.4 19.5 15.0 29.1 18.1 29.1 14.1 39.3 20.0 47.7 20.1 27.6 12.3 22.2 14.1 33.5 18.4 36.3 19.0 15.9 21.6 16.7 18.4 21.7 20.6 24.1 21.4 17.0 14.3 31.1 15.3 21.8 22.0 15.2 8.9 9.6 12.0 10.4 8.7 9.0 10.5 8.8 10.2 8.0 9.9 10.9 18.5 6.4 9.2 12.7 15.5 7.4 15.8 16.5 18.8 7.3 14.3 15.9 26.8 15.7 10.8 12.9 4.2 42.1 15.4 26.8 5.9 11.7 2.2 9.6 16.4 15.6 12.6 7.8 15.3 9.9 30.3 24.1 15.3 9.9 3.8 14.2 16.4 7.3 17.2 8.4 14.2 17.0 12.2 9.0 10.0 2.8 26.4 11.0 10.6 8.4 17.7 8.4 13.4 12.5 13.0 9.3 23.4 21.8 8.4 13.5 36.8 10.0 9.3 11.9 13.1 13.7 23.0 24.8 20.8 15.3 11.1 63.3 13.3 18.1 19.7 19.3 FBXO21 "FBX21, KIAA0875" ENSG00000135108 "F-box protein 21" O94952 12 117141991-117190471 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "fallopian tube: 128.9" "Cell type enhanced" "Detected in all" "Peritubular cells: 222.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062411, HPA071452" Approved Approved Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 68: Epididymis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 44: Endometrium - Transcription" Mitochondria "HPA062411: AB_2684755, HPA071452: AB_2686398" "unprognostic (6.38e-2)" "unprognostic (4.43e-2)" "unprognostic (2.58e-2)" "unprognostic (9.00e-3)" "unprognostic (1.57e-1)" "unprognostic (8.89e-2)" "unprognostic (1.84e-1)" "unprognostic (1.37e-1)" "unprognostic (8.99e-2)" "unprognostic (7.01e-3)" "unprognostic (1.28e-2)" "unprognostic (9.44e-2)" "prognostic favorable (2.05e-8)" "unprognostic (1.69e-2)" "unprognostic (1.17e-1)" "unprognostic (2.01e-1)" "unprognostic (7.29e-2)" 12.2 40.9 21.7 10.7 23.0 8.5 17.5 22.2 24.7 18.5 25.7 15.6 16.5 25.0 110.8 15.4 128.9 17.0 31.1 27.2 29.7 53.7 27.5 17.5 13.7 17.5 18.7 60.3 30.7 24.8 20.2 19.5 17.2 26.5 14.6 24.3 16.5 29.3 23.8 16.9 14.3 19.5 20.4 15.2 18.7 42.2 30.2 13.7 28.3 28.5 14.1 16.2 13.8 23.5 20.3 47.3 29.2 16.2 23.5 24.4 33.4 26.6 28.6 24.3 19.7 30.8 14.0 26.5 25.7 27.3 18.2 27.0 34.7 26.6 29.1 15.0 31.2 1.3 24.9 25.0 21.3 8.7 9.0 24.1 25.1 19.5 31.0 39.7 34.4 23.0 10.7 8.6 21.2 33.0 25.0 6.3 43.7 30.9 30.6 29.3 42.5 27.8 24.4 47.7 57.6 34.9 66.4 17.3 14.5 23.3 40.6 3.5 26.8 16.1 20.7 19.1 17.4 15.0 16.6 34.4 23.5 13.5 23.1 1.2 7.0 4.5 11.6 12.2 12.1 10.4 12.0 12.1 9.7 14.3 13.6 12.6 0.6 11.4 12.7 6.6 13.6 8.8 21.7 23.0 22.2 24.7 27.2 29.7 17.5 18.7 17.2 20.4 30.2 23.5 28.5 32.1 35.4 44.1 44.0 37.2 49.1 29.5 40.5 44.3 32.3 26.7 65.4 42.9 39.6 51.5 41.7 58.3 26.3 16.4 45.0 62.5 37.2 108.6 38.3 46.2 39.0 12.0 50.7 50.5 38.0 44.3 24.5 113.1 3.8 57.0 60.0 38.9 15.6 74.0 51.4 23.7 54.9 22.3 17.2 60.4 99.7 17.3 23.2 23.4 18.4 54.1 16.5 41.7 67.5 36.9 16.4 222.3 23.4 48.8 19.0 95.4 29.9 34.1 105.2 35.3 40.6 21.6 43.9 33.9 45.3 65.5 34.1 44.2 27.2 38.3 FBXW5 "DKFZP434B205, Fbw5, MGC20962" ENSG00000159069 "F-box and WD repeat domain containing 5" Q969U6 9 136940435-136944738 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 251.8" "Cell type enhanced" "Detected in all" "Early spermatids: 581.9;Late spermatids: 1900.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046615 Approved Approved Mitochondria No No "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "HPA046615: AB_10965648" "unprognostic (1.11e-1)" "unprognostic (1.10e-2)" "unprognostic (1.56e-2)" "prognostic favorable (1.02e-4)" "unprognostic (4.26e-2)" "unprognostic (1.29e-1)" "unprognostic (2.22e-2)" "unprognostic (7.16e-3)" "unprognostic (2.64e-2)" "unprognostic (7.05e-2)" "unprognostic (3.51e-3)" "unprognostic (3.23e-2)" "prognostic favorable (4.74e-4)" "unprognostic (1.73e-2)" "unprognostic (3.64e-1)" "unprognostic (2.32e-1)" "unprognostic (2.13e-1)" 54.7 58.1 27.6 23.3 23.0 28.7 47.4 23.4 32.4 36.2 23.4 73.9 42.9 44.1 9.4 70.8 33.9 17.7 117.1 34.7 23.5 54.3 132.4 37.5 22.1 27.0 27.2 29.1 75.7 19.0 41.1 15.5 28.3 56.3 13.4 3.9 54.8 26.9 188.7 42.6 59.3 17.2 24.3 47.6 65.0 251.8 33.0 24.7 42.5 66.0 17.6 59.4 41.5 23.7 39.2 65.5 14.9 36.7 36.6 23.6 85.7 40.6 27.5 27.7 15.3 42.9 48.8 27.0 46.0 42.0 21.5 48.0 13.6 35.3 4.6 35.4 47.2 22.9 88.8 46.8 40.0 34.2 55.2 26.9 31.0 25.4 21.1 21.9 28.9 19.5 46.0 42.7 21.3 98.3 26.2 36.4 26.7 48.1 70.6 28.7 22.5 46.3 24.5 37.9 30.9 30.0 49.0 52.8 54.4 5.7 60.3 52.4 55.8 39.5 35.1 75.1 35.1 33.6 45.1 17.0 55.0 29.7 30.5 62.8 62.1 88.0 97.7 74.3 75.3 39.2 73.9 83.3 59.6 31.1 32.0 53.7 32.9 55.4 61.2 98.8 96.8 72.8 27.6 23.0 23.4 32.4 34.7 23.5 27.0 27.2 28.3 24.3 33.0 23.7 61.3 19.2 45.4 13.1 40.7 28.7 44.5 129.0 26.7 29.9 50.1 48.8 86.9 50.1 72.8 23.9 16.7 68.3 108.0 336.5 74.3 111.7 581.9 29.1 27.5 53.6 67.3 36.8 15.9 148.1 132.9 38.9 98.4 38.6 28.6 116.2 46.1 113.3 88.0 60.6 15.3 153.7 65.1 62.6 49.3 1900.7 51.6 69.2 69.4 8.4 124.9 59.1 83.4 11.1 17.1 132.5 238.0 71.1 59.4 84.6 420.9 134.1 43.5 37.3 59.2 33.5 59.0 224.3 47.4 47.1 35.9 101.4 66.6 49.4 127.6 70.0 FGFR1OP2 DKFZp564O1863 ENSG00000111790 "FGFR1 oncogene partner 2" Q9NVK5 12 26938470-26966650 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 249.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038308, HPA038696" Supported Approved Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 6: Erythroid cells - Oxygen transport" Mitochondria "HPA038308: AB_10672524, HPA038696: AB_10675948" "unprognostic (1.68e-1)" "unprognostic (6.49e-2)" "unprognostic (1.95e-1)" "unprognostic (2.34e-1)" "unprognostic (4.01e-2)" "unprognostic (1.19e-1)" "unprognostic (4.37e-3)" "unprognostic (1.72e-1)" "unprognostic (8.17e-2)" "unprognostic (1.31e-1)" "unprognostic (1.11e-1)" "unprognostic (3.41e-2)" "unprognostic (1.55e-2)" "unprognostic (6.82e-2)" "unprognostic (1.40e-1)" "unprognostic (5.33e-2)" "unprognostic (1.36e-2)" 29.4 41.6 29.0 30.6 32.6 61.6 26.3 28.6 48.3 24.9 21.0 23.1 23.1 31.6 29.0 23.1 23.7 28.7 28.5 34.2 28.1 30.9 27.8 25.7 42.4 29.2 28.6 59.5 15.1 19.3 17.8 27.1 29.3 19.9 20.0 30.7 18.2 18.6 23.3 23.5 22.9 26.6 29.8 33.2 20.5 23.0 27.5 36.2 24.1 32.8 30.9 25.2 21.1 44.3 30.3 36.9 30.5 41.1 51.9 37.4 44.2 51.6 60.1 39.1 42.5 57.3 34.4 44.3 24.8 45.9 37.4 31.4 21.3 38.8 55.5 33.6 31.1 75.0 39.4 38.4 61.3 43.5 54.9 27.3 24.8 47.7 61.6 53.3 56.8 39.6 45.3 33.0 46.2 36.3 58.0 103.3 50.4 39.1 59.9 34.6 84.2 37.1 34.8 36.5 9.3 18.5 58.9 21.5 52.1 69.9 38.5 65.3 61.7 51.6 52.0 95.9 48.5 23.1 25.2 93.4 43.2 50.2 42.7 81.1 31.5 40.6 31.6 31.4 28.3 22.3 33.0 30.7 25.2 19.7 29.8 33.3 32.0 25.9 31.3 20.6 61.3 23.7 29.0 32.6 28.6 48.3 34.2 28.1 29.2 28.6 29.3 29.8 27.5 44.3 70.8 38.5 37.2 39.2 97.1 140.3 62.3 30.6 86.0 52.7 45.4 39.6 45.4 24.3 41.2 27.6 77.2 41.5 114.1 19.9 72.4 28.9 17.9 28.9 47.8 70.1 26.9 249.0 79.4 23.1 37.8 86.5 23.0 30.8 59.5 77.9 70.6 30.7 60.6 58.9 30.6 22.0 26.4 64.7 96.2 18.8 105.3 74.6 88.9 47.8 49.6 64.3 83.4 63.8 128.5 29.7 29.0 170.8 138.2 56.7 27.2 70.0 20.8 48.0 46.0 69.6 81.4 32.9 70.1 57.4 119.8 59.5 141.2 42.9 20.0 63.5 FKBP10 "FKBP6, FKBP65, FLJ20683, FLJ22041, FLJ23833, hFKBP65" ENSG00000141756 "FKBP prolyl isomerase 10" Q96AY3 17 41812680-41823213 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Isomerase, Rotamase" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 79.1;Fibroblasts: 100.0;Sertoli cells: 59.2;Smooth muscle cells: 65.3;Theca cells: 54.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 551.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051171, HPA057021" Enhanced Approved Mitochondria "Intracellular and membrane" NA NA 110000 "Cluster 22: NK-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Mitochondria "HPA051171: AB_2681371, HPA057021: AB_2683312" "unprognostic (8.30e-2)" "prognostic unfavorable (4.16e-4)" "unprognostic (9.05e-2)" "unprognostic (1.71e-2)" "unprognostic (4.77e-2)" "unprognostic (2.95e-2)" "unprognostic (1.14e-2)" "unprognostic (9.98e-2)" "unprognostic (2.21e-2)" "unprognostic (7.57e-2)" "unprognostic (1.14e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.34e-2)" "unprognostic (5.77e-2)" "prognostic unfavorable (3.43e-5)" "prognostic unfavorable (4.99e-4)" 39.4 39.5 20.9 27.1 22.2 0.5 33.5 21.7 26.1 64.0 22.0 29.1 7.6 61.5 16.9 13.9 50.9 46.0 45.6 20.3 22.1 17.7 7.8 37.8 10.9 24.6 21.6 58.4 15.1 48.5 56.7 60.7 22.2 32.6 10.8 6.0 14.7 30.8 7.6 20.4 19.1 55.6 21.9 14.3 18.5 9.0 24.2 4.9 34.9 9.3 4.4 42.2 39.1 21.6 0.7 119.6 110.7 363.3 379.3 441.7 92.0 490.4 497.4 185.6 159.0 62.1 4.8 0.3 6.6 551.9 45.9 0.8 66.7 133.4 77.9 33.0 99.9 48.6 132.1 181.0 411.4 0.0 0.6 476.1 0.5 150.3 115.5 352.6 158.8 0.0 1.9 16.7 157.0 163.2 0.3 0.1 85.4 258.0 38.3 9.9 125.2 15.7 31.7 0.1 26.7 92.1 0.7 349.3 166.0 137.4 54.1 3.1 181.0 219.0 111.5 145.8 76.0 0.8 0.2 0.3 299.7 0.0 213.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 20.9 22.2 21.7 26.1 20.3 22.1 24.6 21.6 22.2 21.9 24.2 21.6 14.9 0.0 4.8 38.2 0.2 8.5 11.5 2.7 1.2 0.6 10.8 13.2 2.3 1.5 1.4 0.0 0.0 6.1 0.2 0.1 0.0 8.7 0.7 3.0 79.1 34.9 0.0 0.0 0.3 4.7 30.8 100.0 1.5 4.6 0.0 32.9 30.4 0.0 4.7 15.2 0.3 1.3 0.0 0.0 9.7 2.9 46.9 1.5 16.0 15.0 0.0 32.0 0.0 17.1 0.1 2.2 0.1 44.8 0.5 8.2 0.0 0.0 0.1 1.1 59.2 35.2 65.3 0.9 7.6 0.5 5.1 11.9 2.1 54.0 0.6 1.6 FKBP9 "FKBP60, FKBP63" ENSG00000122642 "FKBP prolyl isomerase 9" O95302 7 32957404-33006930 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 108.6;Fibroblasts: 89.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 379.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012595, HPA055256" Approved Approved "Golgi apparatus,Vesicles,Mitochondria" "Intracellular and membrane" No No 63000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Mitochondria" Vesicles "HPA012595: AB_1848629, HPA055256: AB_2682761" "unprognostic (1.23e-2)" "prognostic unfavorable (4.22e-4)" "unprognostic (6.94e-2)" "unprognostic (6.25e-3)" "prognostic unfavorable (5.80e-4)" "prognostic unfavorable (2.02e-4)" "prognostic unfavorable (8.69e-4)" "unprognostic (3.40e-2)" "unprognostic (9.59e-2)" "unprognostic (2.58e-1)" "unprognostic (3.63e-2)" "unprognostic (3.30e-2)" "unprognostic (1.36e-2)" "unprognostic (6.31e-2)" "unprognostic (1.97e-1)" "unprognostic (8.90e-3)" "prognostic unfavorable (7.02e-6)" 80.7 44.8 23.9 16.8 24.0 2.3 59.1 26.5 25.3 65.9 28.1 44.8 19.7 55.7 22.4 35.6 50.6 44.4 77.1 21.4 32.1 38.2 21.1 49.6 13.6 28.9 30.2 46.3 40.8 25.1 34.8 77.4 29.3 42.3 45.3 11.7 36.0 52.1 35.0 64.4 31.0 74.4 28.0 23.7 41.0 11.4 34.2 8.2 40.8 49.7 15.8 43.3 52.2 27.9 38.9 71.4 27.6 113.4 254.1 290.2 36.4 202.6 209.9 65.5 103.9 31.6 89.2 0.2 80.7 379.5 105.1 73.3 40.8 100.0 75.2 0.1 11.9 6.6 72.3 31.6 105.6 0.4 10.8 191.8 59.6 59.0 56.9 156.3 83.9 0.1 15.0 7.7 137.3 37.1 0.2 19.4 5.8 76.6 37.3 0.3 73.7 0.3 73.0 13.0 25.7 62.4 115.6 58.4 73.4 69.6 41.1 18.7 112.8 107.0 99.8 67.4 46.8 23.9 48.9 0.2 104.4 0.3 218.5 0.9 2.2 0.5 0.0 1.6 0.0 0.2 0.0 0.0 0.8 0.1 0.1 0.0 4.0 0.1 0.4 0.1 0.0 0.6 23.9 24.0 26.5 25.3 21.4 32.1 28.9 30.2 29.3 28.0 34.2 27.9 108.6 12.8 21.7 22.9 0.6 34.3 12.7 31.4 10.2 8.2 15.7 16.5 46.1 17.2 10.3 18.4 10.4 18.8 0.6 23.2 5.9 19.5 0.5 22.6 25.8 80.1 12.2 1.7 9.8 41.5 27.7 89.1 17.9 23.0 5.7 81.0 60.0 18.0 7.6 11.8 10.2 25.4 10.2 8.6 23.5 3.2 36.7 5.4 60.5 15.0 2.9 30.5 0.0 8.5 8.8 36.5 22.1 55.3 4.4 8.1 18.8 8.1 11.0 5.2 46.0 21.2 45.8 1.0 1.3 12.1 28.6 13.1 3.1 12.3 27.7 10.5 FMC1 "C7orf55, HSPC268" ENSG00000164898 "Formation of mitochondrial complex V assembly factor 1 homolog" Q96HJ9 7 139339457-139346328 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting duct cells: 84.6;Distal tubular cells: 199.6;Proximal tubular cells: 196.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEK 293: 67.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045663, HPA050553" Approved Approved Mitochondria NA NA "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA045663: AB_2679410, HPA050553: AB_2681173" "unprognostic (3.71e-2)" "unprognostic (1.15e-2)" "unprognostic (3.69e-1)" "unprognostic (3.80e-2)" "unprognostic (8.90e-2)" "unprognostic (9.00e-2)" "unprognostic (4.39e-2)" "prognostic favorable (1.08e-4)" "unprognostic (2.19e-1)" "prognostic favorable (5.63e-6)" "unprognostic (1.04e-3)" "unprognostic (2.39e-2)" "prognostic favorable (2.05e-5)" "unprognostic (1.50e-1)" "unprognostic (3.40e-2)" "unprognostic (4.67e-1)" "unprognostic (3.02e-2)" 8.5 11.5 19.1 2.8 20.1 6.2 8.2 20.1 23.1 6.6 20.0 9.7 7.0 8.1 11.6 5.5 9.3 5.2 28.5 19.3 19.8 16.2 17.7 5.2 5.5 20.0 19.8 11.2 10.3 11.1 12.0 3.3 19.9 11.2 5.1 3.1 12.8 7.7 30.5 5.0 7.0 3.7 19.5 6.4 11.3 5.7 19.6 7.5 10.7 39.0 3.0 8.6 5.8 21.5 5.6 19.5 11.2 11.7 6.0 5.2 4.9 1.8 4.6 13.2 9.8 6.6 7.1 12.6 11.3 5.9 10.5 4.3 11.0 4.8 3.2 6.3 67.5 6.1 19.9 29.3 12.8 5.3 8.8 13.5 9.3 4.4 3.7 4.8 10.8 8.6 12.4 18.9 7.6 39.2 12.8 35.7 11.1 9.9 28.2 7.7 5.5 17.6 11.1 5.0 22.1 14.5 6.3 5.2 8.1 1.8 2.5 4.3 5.1 4.7 4.4 5.6 5.0 6.7 7.2 14.4 12.1 11.7 7.7 13.3 10.3 10.9 11.2 6.7 9.9 25.3 13.7 11.4 12.0 20.5 15.7 11.2 3.3 16.1 7.6 21.4 16.9 6.6 19.1 20.1 20.1 23.1 19.3 19.8 20.0 19.8 19.9 19.5 19.6 21.5 31.3 44.8 47.6 0.0 10.1 0.0 0.0 0.0 0.0 0.0 57.1 57.4 0.0 0.0 19.8 84.6 0.0 63.0 11.9 0.0 199.6 35.4 0.0 67.8 40.1 14.5 0.0 0.0 0.0 35.3 24.2 20.3 0.0 43.9 12.6 27.6 0.0 0.0 39.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.3 0.0 0.0 12.9 0.0 0.0 0.0 0.0 23.6 0.0 0.0 4.1 0.0 0.0 196.2 37.2 0.0 0.0 0.0 20.8 0.0 0.0 0.0 0.0 47.6 9.4 40.9 0.0 0.0 FN3K ENSG00000167363 "Fructosamine 3 kinase" Q9H479 17 82735615-82751196 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 79.8" "Cell type enhanced" "Detected in many" "Distal tubular cells: 90.1;Proximal tubular cells: 167.2;Rod photoreceptor cells: 72.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 34.3;Hep G2: 66.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059151, HPA061358" Supported Approved Mitochondria NA NA 180000 "Cluster 35: Non-specific - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA059151: AB_2683931, HPA061358: AB_2684490" "unprognostic (4.74e-2)" "unprognostic (9.19e-2)" "unprognostic (4.22e-2)" "prognostic favorable (1.10e-4)" "unprognostic (6.10e-2)" "unprognostic (1.39e-1)" "unprognostic (6.45e-2)" "unprognostic (9.86e-2)" "unprognostic (5.08e-2)" "unprognostic (2.61e-1)" "prognostic favorable (2.40e-4)" "unprognostic (6.66e-2)" "prognostic favorable (1.39e-6)" "unprognostic (2.68e-2)" "unprognostic (8.02e-2)" "unprognostic (4.77e-1)" "unprognostic (1.22e-2)" 14.4 47.3 47.4 2.9 64.3 12.0 8.4 64.4 56.6 10.4 36.8 15.5 22.4 9.4 7.0 4.6 12.5 6.9 47.5 46.5 54.3 49.6 48.1 7.8 2.4 63.3 56.8 22.3 18.1 21.9 22.4 5.3 62.7 12.5 9.5 13.8 28.5 12.1 23.5 5.3 14.5 6.6 49.4 4.6 17.4 5.2 55.6 1.0 10.2 10.9 2.3 8.8 7.9 79.8 1.3 16.1 4.4 23.2 6.9 5.7 2.9 2.9 2.2 5.4 2.7 21.0 3.3 0.2 3.9 2.6 4.5 0.6 34.3 2.5 2.0 1.0 2.4 12.5 12.9 66.2 18.8 0.3 10.1 4.9 9.0 2.1 0.0 5.7 10.6 1.0 22.4 0.6 1.1 1.8 0.2 0.2 2.9 7.6 13.0 2.1 0.3 0.1 11.5 4.5 7.0 22.7 5.3 1.2 15.8 3.8 15.4 4.5 2.5 0.4 1.6 5.6 4.3 1.2 0.3 0.1 0.4 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.4 64.3 64.4 56.6 46.5 54.3 63.3 56.8 62.7 49.4 55.6 79.8 3.9 3.2 2.0 8.8 1.9 1.5 3.7 1.5 14.8 41.9 4.5 3.7 5.8 4.3 2.5 31.3 47.9 11.7 2.6 5.7 90.1 3.2 0.2 11.6 3.0 5.2 5.4 49.2 10.2 1.2 2.6 8.6 47.9 25.9 1.3 6.9 4.2 5.4 8.2 32.0 13.0 10.4 6.1 1.0 3.4 0.4 5.3 5.7 12.4 5.6 1.2 36.2 1.0 6.0 17.1 1.7 7.3 3.0 9.1 3.9 28.2 167.2 2.5 72.9 0.0 6.1 9.8 0.8 4.1 12.8 1.8 8.3 3.1 18.6 9.5 3.5 FOXB1 "FKH5, HFKH-5" ENSG00000171956 "Forkhead box B1" Q99853 15 60004234-60061730 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 34 "brain: 21.6" "Cell type enriched" "Detected in some" 4 "Early spermatids: 32.5" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.2" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "T-reg: 1.1" "Lineage enriched" "Detected in single" 12 "T-cells: 1.1" "Cell line enhanced" "Detected in some" "AF22: 6.6;HDLM-2: 14.7;HEK 293: 10.7;JURKAT: 5.6" "Region enhanced" "Detected in many" "hypothalamus: 6.6" "Low region specificity" "Detected in many" HPA073369 Approved Nucleoplasm,Mitochondria NA NA "Cluster 35: T-regs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoplasm, Mitochondria" "HPA073369: AB_2686597" "unprognostic (1.69e-1)" "unprognostic (3.33e-2)" "unprognostic (1.14e-1)" "unprognostic (7.40e-3)" "unprognostic (1.33e-3)" "unprognostic (1.17e-2)" "unprognostic (1.47e-2)" "unprognostic (5.32e-4)" "unprognostic (1.06e-1)" "unprognostic (9.21e-2)" "unprognostic (3.21e-1)" "unprognostic (8.12e-9)" "unprognostic (8.74e-2)" "unprognostic (1.74e-1)" "unprognostic (9.38e-2)" 0.0 0.0 2.0 0.0 3.0 0.0 0.0 5.4 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 21.6 0.0 0.0 0.0 0.2 9.7 8.5 0.0 0.0 0.0 0.0 0.2 5.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.2 0.0 0.2 0.6 9.5 0.0 0.0 0.0 0.0 0.0 0.0 4.1 2.5 0.0 6.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 14.7 10.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 1.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 2.0 3.0 5.4 0.8 0.2 21.6 9.7 8.5 5.8 8.2 9.5 4.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.7 0.1 0.1 0.0 0.0 32.5 7.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 3.6 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 6.8 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 4.8 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 FOXN4 ENSG00000139445 "Forkhead box N4" Q96NZ1 12 109277978-109309284 "Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 11.4" "Cell type enhanced" "Detected in some" "Early spermatids: 1.9;Endometrial ciliated cells: 2.6;Ionocytes: 2.0;Respiratory ciliated cells: 1.2;Spermatocytes: 2.8;Spermatogonia: 3.0" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.3;SCLC-21H: 3.5;SH-SY5Y: 3.6;U-266/70: 5.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA050018 Uncertain Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Mitochondria" Cytosol "HPA050018: AB_2680992" "unprognostic (1.09e-3)" "unprognostic (9.63e-2)" "unprognostic (1.60e-1)" "unprognostic (1.22e-1)" "unprognostic (1.08e-1)" "unprognostic (2.52e-2)" "unprognostic (1.18e-1)" "unprognostic (3.27e-2)" "unprognostic (7.93e-3)" "unprognostic (2.30e-1)" "unprognostic (1.02e-3)" "unprognostic (1.05e-1)" "unprognostic (1.43e-1)" "unprognostic (6.00e-2)" 0.3 0.0 0.2 0.0 0.1 0.0 0.1 0.2 0.2 1.8 0.5 0.3 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.3 0.8 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.2 0.2 0.0 0.1 0.1 0.0 0.0 11.4 0.2 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 3.6 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.2 0.1 0.1 0.2 0.2 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 2.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.2 0.1 2.8 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FRAT2 ENSG00000181274 "FRAT regulator of WNT signaling pathway 2" O75474 10 97332497-97334729 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in all" 4 "testis cancer: 70.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 15.0;neutrophil: 58.2" "Lineage enriched" "Detected in all" 7 "granulocytes: 58.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049763 Uncertain Approved Nucleoplasm,Mitochondria No No "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Mitochondria "HPA049763: AB_2680868" "unprognostic (4.93e-2)" "unprognostic (1.28e-2)" "unprognostic (2.13e-1)" "unprognostic (1.46e-1)" "unprognostic (4.04e-3)" "unprognostic (1.87e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (3.17e-3)" "unprognostic (2.60e-1)" "unprognostic (8.02e-2)" "unprognostic (4.60e-2)" "unprognostic (3.25e-2)" "prognostic favorable (2.55e-4)" "unprognostic (7.87e-3)" "unprognostic (4.83e-2)" "unprognostic (2.34e-1)" "unprognostic (9.08e-2)" 5.3 3.6 7.2 10.4 7.1 31.0 8.0 7.7 7.4 6.0 9.8 17.1 25.1 4.1 6.2 14.4 7.1 4.0 6.0 6.3 6.8 7.8 18.3 9.7 8.7 7.7 7.6 2.8 14.0 5.2 3.0 7.4 6.8 7.9 15.5 3.3 15.1 4.3 10.1 20.4 15.9 4.1 7.0 28.9 13.2 14.6 7.5 8.9 5.3 9.1 10.8 6.7 8.1 6.0 10.9 4.3 6.9 31.2 4.9 4.0 25.7 2.4 8.9 3.7 3.7 6.8 12.5 13.3 8.4 2.5 2.2 20.3 18.3 9.5 2.9 20.0 28.0 17.9 9.2 15.0 2.8 28.9 20.6 3.2 20.0 3.6 11.4 7.9 9.3 11.7 15.8 4.2 1.8 17.9 12.6 36.5 42.9 36.2 17.5 12.8 2.9 19.1 8.9 9.8 12.5 10.2 3.1 19.1 12.6 28.0 28.8 44.8 4.2 2.2 2.7 1.7 6.4 11.4 12.5 6.6 2.6 49.3 0.8 8.3 7.2 15.0 1.1 4.8 0.6 1.1 1.3 1.8 3.8 3.2 2.2 1.3 58.2 1.6 7.9 1.0 0.7 2.3 7.2 7.1 7.7 7.4 6.3 6.8 7.7 7.6 6.8 7.0 7.5 6.0 18.2 0.0 3.9 2.9 15.7 31.7 25.3 6.6 46.1 19.7 24.7 19.6 6.4 20.0 5.0 14.7 4.2 6.1 26.1 31.0 11.7 2.2 40.7 39.6 9.7 10.3 13.8 14.5 2.0 5.3 18.5 6.4 37.2 46.3 1.3 16.7 8.6 11.3 8.6 11.8 2.8 30.6 4.1 28.3 9.0 42.3 2.1 25.2 10.6 7.5 24.7 5.0 14.4 2.0 1.1 3.4 21.6 2.6 8.4 30.0 13.5 3.7 4.5 18.1 0.0 14.9 8.7 2.3 4.4 37.7 52.7 7.8 18.8 20.1 31.6 32.3 FRMD6 "C14orf31, EX1, MGC17921, willin" ENSG00000139926 "FERM domain containing 6" Q96NE9 14 51489100-51730727 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 160.6;Early spermatids: 219.1;Late spermatids: 473.0;Suprabasal keratinocytes: 137.5;Urothelial cells: 130.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 351.1;fHDF/TERT166: 765.6;U-138 MG: 290.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001297 Uncertain Supported Approved Mitochondria NA NA "Cluster 10: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "HPA001297: AB_1078913" "unprognostic (1.30e-1)" "unprognostic (1.09e-1)" "unprognostic (1.84e-1)" "unprognostic (2.29e-1)" "unprognostic (2.64e-2)" "unprognostic (8.05e-2)" "unprognostic (8.19e-2)" "unprognostic (3.55e-3)" "unprognostic (1.28e-1)" "unprognostic (2.45e-2)" "prognostic unfavorable (2.66e-4)" "unprognostic (3.18e-2)" "prognostic unfavorable (1.28e-4)" "prognostic unfavorable (3.50e-4)" "unprognostic (1.18e-1)" "unprognostic (2.11e-2)" "unprognostic (1.20e-2)" 12.1 13.4 5.2 9.5 5.2 1.2 27.1 12.6 6.7 28.1 8.4 16.0 5.2 53.6 11.3 59.8 13.4 33.0 7.3 6.4 4.5 4.2 10.4 8.6 5.5 5.7 8.1 25.9 5.0 2.4 3.4 14.1 4.9 27.7 10.8 1.5 21.5 30.7 7.4 43.2 7.5 46.8 5.4 12.0 7.2 31.0 5.8 12.6 6.6 6.8 12.7 31.5 30.1 5.6 71.4 14.1 20.1 42.1 40.1 67.6 8.8 351.1 163.2 169.5 146.0 51.9 16.4 1.9 10.6 765.6 47.6 82.8 5.7 113.8 200.3 1.1 8.6 0.3 7.6 2.2 46.8 0.2 4.2 58.8 40.9 152.0 200.5 77.8 52.6 3.7 0.7 24.6 181.8 12.2 7.1 0.2 3.9 0.2 27.4 0.8 79.1 0.7 33.4 113.7 4.1 44.9 27.8 3.9 31.3 37.7 3.0 1.0 242.6 290.7 97.6 73.3 73.5 18.9 17.3 0.2 19.3 0.3 114.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.1 0.0 0.0 0.1 5.2 5.2 12.6 6.7 6.4 4.5 5.7 8.1 4.9 5.4 5.8 5.6 6.9 3.2 1.5 34.6 0.8 111.4 160.6 42.4 41.5 0.4 40.5 49.4 2.9 8.6 11.6 0.0 0.0 40.1 1.5 0.0 0.0 16.9 219.1 2.0 41.1 14.4 0.0 2.5 45.2 2.9 4.8 57.8 1.1 3.6 1.3 0.9 9.3 4.2 3.8 0.0 22.5 0.3 10.2 0.3 21.1 473.0 17.7 1.5 32.0 68.4 0.7 8.2 0.0 74.9 5.9 64.0 0.0 22.2 3.7 52.0 0.1 0.4 2.7 0.5 6.6 24.5 28.0 10.2 9.8 115.7 137.5 39.0 3.3 0.9 0.1 130.7 FSIP2 FLJ34780 ENSG00000188738 "Fibrous sheath interacting protein 2" Q5CZC0 2 185738804-185833290 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 18.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 137.8;Alveolar cells type 2: 93.8;Early spermatids: 289.6;Gastric mucus-secreting cells: 68.3;Spermatocytes: 124.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RT4: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA036139 Approved Microtubules,Mitochondria NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 15: RT4 - Unknown function" "Cluster 23: Spermatids - Flagellum & Golgi organization" Microtubules Mitochondria "HPA036139: AB_10602134" "unprognostic (5.28e-2)" "unprognostic (1.20e-2)" "unprognostic (4.17e-1)" "unprognostic (5.81e-2)" "unprognostic (1.67e-1)" "unprognostic (2.95e-1)" "unprognostic (6.31e-2)" "unprognostic (2.76e-3)" "unprognostic (1.55e-1)" "unprognostic (5.24e-2)" "unprognostic (4.37e-3)" "unprognostic (2.79e-3)" "unprognostic (4.89e-3)" "unprognostic (1.28e-1)" "unprognostic (7.52e-2)" "unprognostic (5.17e-2)" "unprognostic (4.64e-5)" 0.1 0.2 0.3 0.2 0.5 0.0 0.2 0.3 0.3 0.2 0.0 1.5 0.0 0.2 0.2 0.0 0.1 0.1 0.1 0.2 0.3 0.1 0.0 0.0 0.0 0.5 0.4 0.2 0.2 0.2 0.4 0.1 0.6 0.2 0.9 0.6 0.2 0.0 0.0 0.2 0.2 0.0 0.6 0.0 2.6 18.3 0.3 0.1 0.2 0.0 0.0 0.2 0.1 0.9 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.6 0.2 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.3 0.3 0.2 0.3 0.5 0.4 0.6 0.6 0.3 0.9 1.7 137.8 93.8 5.2 2.6 0.5 0.1 1.4 1.8 16.3 3.0 1.7 3.9 0.0 31.5 0.0 10.4 0.3 1.0 26.0 0.0 0.7 289.6 3.3 3.3 5.6 7.7 0.0 4.5 0.2 0.1 7.3 68.3 2.1 40.4 2.7 1.8 0.1 0.4 18.5 5.4 19.7 0.0 0.8 1.0 50.8 2.1 5.9 1.8 3.7 0.7 3.9 2.1 23.6 14.0 5.4 5.5 3.8 1.3 0.2 0.5 0.2 46.0 7.2 0.0 4.0 0.8 124.4 5.4 0.2 0.3 0.3 6.0 2.6 5.2 0.2 FXYD2 "ATP1G1, HOMG2, MGC12372" ENSG00000137731 "FXYD domain containing ion transport regulator 2" P54710 11 117800844-117828698 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Disease variant, FDA approved drug targets, Primary hypomagnesemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "kidney: 3645.4" "Group enriched" "Detected in many" 5 "Cholangiocytes: 1595.6;Distal tubular cells: 2952.4;Ductal cells: 892.8;Proximal tubular cells: 3423.7" "Cancer enriched" "Detected in some" 8 "renal cancer: 49.9" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 4 "memory CD8 T-cell: 14.8;naive CD4 T-cell: 5.1;naive CD8 T-cell: 4.3;NK-cell: 9.6;plasmacytoid DC: 3.8" "Group enriched" "Detected in many" 7 "dendritic cells: 3.8;NK-cells: 9.6;T-cells: 14.8" "Group enriched" "Detected in some" 25 "MOLT-4: 2255.4;RPTEC TERT1: 4711.9" "Low region specificity" "Detected in many" "Region enriched" "Detected in some" 5 "spinal cord: 27.7" "HPA064218, HPA068838" Supported Approved Mitochondria NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA064218: AB_2685214, HPA068838: AB_2686047" "unprognostic (4.11e-4)" "unprognostic (1.14e-2)" "unprognostic (1.63e-1)" "unprognostic (1.36e-3)" "unprognostic (1.09e-3)" "unprognostic (2.30e-2)" "unprognostic (3.65e-2)" "unprognostic (4.62e-1)" "unprognostic (4.01e-2)" "unprognostic (4.91e-2)" "unprognostic (1.24e-2)" "unprognostic (2.64e-1)" "prognostic favorable (3.23e-9)" "unprognostic (3.22e-3)" "unprognostic (4.38e-2)" "unprognostic (4.62e-1)" "unprognostic (3.00e-2)" 2.0 0.9 0.7 1.4 0.6 3.3 1.2 1.4 1.7 1.0 0.0 2.1 1.4 1.5 1.2 0.8 1.8 353.1 1.2 0.8 0.0 3645.4 23.8 4.4 8.9 0.0 0.1 2.4 612.6 0.2 1.6 0.8 0.0 1.7 0.8 1.1 835.6 0.7 0.3 1.0 1.6 2.2 0.0 3.1 2.8 0.6 0.0 74.8 1.0 0.6 4.5 1.8 0.9 0.4 0.0 118.6 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.4 3.5 0.0 0.2 0.4 0.2 0.0 0.3 0.2 0.0 0.1 0.2 83.6 0.1 0.2 0.7 0.0 0.0 0.0 0.0 0.0 1.9 140.3 0.0 0.0 0.2 0.3 2255.4 0.0 1.2 0.0 0.0 0.6 0.0 4.6 4711.9 0.0 1.9 0.0 0.0 2.9 0.2 0.2 0.8 0.3 0.8 0.0 1.3 0.5 0.0 1.0 0.3 0.2 0.1 0.2 0.0 0.0 1.2 0.0 1.0 0.0 1.0 0.2 1.8 14.8 0.2 0.3 5.1 4.3 0.0 9.6 0.0 3.8 1.7 2.1 0.7 0.6 1.4 1.7 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.4 1.0 0.0 0.6 0.0 33.6 1.1 0.1 0.8 0.6 0.2 0.1 0.5 1.2 1595.6 0.1 435.9 0.0 0.1 0.7 0.0 2952.4 892.8 21.8 1.6 4.1 2.2 15.1 2.7 0.0 10.0 0.1 3.5 0.5 41.3 0.0 0.6 4.2 3.9 3.6 0.0 0.0 0.3 16.2 4.5 4.1 25.9 9.3 24.8 0.0 0.0 8.8 0.5 1.0 0.0 0.0 23.2 0.0 7.5 0.4 0.2 0.0 3423.7 0.1 3.3 6.6 1.6 3.8 0.3 0.3 0.2 0.9 0.3 27.7 1.2 0.1 0.0 GART "GARS-AIRS-GART, PGFT, PRGS" ENSG00000159131 "Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase" P22102 21 33503931-33543491 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Purine biosynthesis" "Ligase, Multifunctional enzyme, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002119, HPA005779" Approved Approved Mitochondria,Cytosol NA NA 300000 "Cluster 27: Non-specific - Gene expression" "Cluster 3: T-cells - Adaptive immune response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" Cytosol Mitochondria "HPA002119: AB_1849482, HPA005779: AB_1849484" "unprognostic (3.77e-2)" "unprognostic (2.25e-2)" "unprognostic (4.51e-3)" "unprognostic (1.72e-2)" "unprognostic (2.30e-2)" "prognostic unfavorable (5.05e-5)" "prognostic unfavorable (9.82e-5)" "unprognostic (2.50e-2)" "unprognostic (2.76e-3)" "unprognostic (2.92e-1)" "prognostic unfavorable (2.19e-4)" "unprognostic (1.98e-3)" "prognostic unfavorable (3.95e-6)" "unprognostic (1.36e-2)" "unprognostic (2.31e-1)" "unprognostic (2.28e-1)" "unprognostic (1.57e-1)" 24.1 20.3 9.2 24.2 12.2 18.8 24.3 11.3 11.9 16.4 10.1 23.2 22.1 18.3 17.1 24.8 21.8 15.9 20.7 8.6 10.5 21.0 29.7 16.0 30.3 11.0 10.3 19.0 22.3 19.9 12.8 26.1 11.7 17.0 29.1 20.9 16.8 16.7 29.1 17.4 19.4 26.3 11.3 20.0 19.7 29.3 10.9 34.4 20.8 21.9 38.6 32.2 16.5 14.0 132.2 61.5 90.3 98.8 61.1 64.2 100.3 82.6 70.8 96.8 101.5 117.7 108.9 174.8 48.5 55.6 124.9 67.9 189.0 130.4 138.3 91.3 111.7 265.2 68.5 78.6 85.2 148.6 66.3 57.3 86.5 113.3 162.5 48.1 91.5 138.4 312.4 108.5 84.9 63.6 158.2 100.0 194.4 186.3 71.8 131.1 166.6 246.7 74.7 69.4 93.1 84.1 116.9 89.1 107.1 81.0 113.0 93.9 68.7 64.9 76.9 56.1 90.9 106.8 159.6 193.0 67.1 171.3 96.2 9.0 24.0 16.3 25.9 33.9 31.4 29.7 25.2 27.1 31.6 24.5 26.4 26.2 10.6 43.9 30.6 23.2 34.1 22.8 9.2 12.2 11.3 11.9 8.6 10.5 11.0 10.3 11.7 11.3 10.9 14.0 21.1 19.2 19.8 17.3 30.1 46.0 50.3 34.1 38.1 18.5 18.6 17.3 19.3 11.5 28.0 14.7 35.5 41.2 21.8 12.4 23.5 28.4 21.7 23.3 36.9 21.9 13.1 40.3 19.1 24.2 37.4 27.2 21.4 23.4 7.6 31.8 16.1 18.0 23.6 5.0 21.1 17.1 22.4 17.0 12.0 6.6 17.4 17.0 12.4 10.3 19.8 13.3 22.6 17.6 19.3 31.5 12.7 18.0 22.7 54.3 16.4 14.3 17.8 28.5 13.1 23.0 23.9 57.2 27.6 34.4 45.9 25.6 21.2 55.0 24.1 46.6 GATD3A "C21orf33, D21S2048E, ES1, GT335, HES1, KNP-I, KNP-Ia, KNPH, KNPI" ENSG00000160221 "Glutamine amidotransferase like class 1 domain containing 3A" P0DPI2 21 44133610-44210114 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 178.6" "Cell type enhanced" "Detected in some" "Breast glandular cells: 7.0;Granulosa cells: 4.6;Hofbauer cells: 8.6;Proximal tubular cells: 4.8;Theca cells: 11.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 156.3;U-266/70: 128.2;U-266/84: 117.9" HPA018517 Supported Approved Centrosome,Mitochondria "Intracellular and membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" Mitochondria Centrosome "HPA018517: AB_2669899" "unprognostic (9.61e-3)" "unprognostic (2.13e-1)" "unprognostic (1.27e-1)" "unprognostic (1.71e-1)" "unprognostic (2.85e-2)" "unprognostic (3.80e-2)" "unprognostic (1.54e-3)" "unprognostic (6.57e-2)" "unprognostic (8.19e-2)" "unprognostic (1.36e-2)" "unprognostic (8.61e-3)" "unprognostic (9.43e-2)" "unprognostic (4.60e-3)" "unprognostic (1.97e-3)" "unprognostic (1.40e-1)" "unprognostic (6.96e-2)" "unprognostic (1.30e-2)" 21.3 25.3 10.4 7.7 11.8 1.3 18.6 12.2 50.3 18.9 8.2 19.0 2.0 12.1 25.7 19.8 27.4 1.3 68.4 10.3 11.9 51.0 78.2 12.3 8.0 15.0 13.5 18.8 18.2 18.3 16.0 5.8 12.8 16.6 1.0 6.1 18.2 7.8 60.2 17.1 15.7 1.0 12.3 16.3 19.2 11.3 13.4 8.2 15.2 178.6 20.7 18.3 15.1 12.7 1.8 3.7 2.6 0.7 34.4 34.0 52.0 64.2 39.7 49.2 38.9 82.4 0.6 156.3 0.9 0.2 1.6 0.8 0.4 35.3 25.1 35.0 77.7 8.0 11.3 49.0 38.3 3.1 1.1 0.4 2.8 15.7 1.9 29.5 2.2 40.0 31.7 56.5 19.7 6.5 1.6 3.9 1.4 4.9 9.0 1.6 0.8 28.4 2.6 1.2 55.8 0.6 1.3 1.6 52.7 1.0 2.8 4.4 33.8 22.7 1.4 38.1 0.8 128.2 117.9 2.5 1.7 10.2 29.5 10.8 16.4 9.6 16.9 24.9 15.6 27.4 21.5 21.3 3.7 28.1 17.6 15.1 7.6 21.0 40.4 17.6 18.5 23.1 10.4 11.8 12.2 50.3 10.3 11.9 15.0 13.5 12.8 12.3 13.4 12.7 4.3 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 7.0 2.5 0.0 0.0 0.0 0.0 0.0 2.6 3.4 0.0 3.9 1.6 0.0 2.6 1.1 2.1 0.0 0.0 0.0 2.5 3.6 1.9 0.0 1.9 0.0 4.6 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.5 0.0 0.0 4.8 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 2.6 0.8 11.9 0.0 0.0 GATD3B ENSG00000280071 "Glutamine amidotransferase like class 1 domain containing 3B" A0A0B4J2D5 21 5079294-5128413 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Distal tubular cells: 17.6;Ductal cells: 6.9;Hofbauer cells: 8.0;monocytes: 7.8;Proximal tubular cells: 31.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA018517 Uncertain Approved Centrosome,Mitochondria "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria Centrosome "HPA018517: AB_2669899" "unprognostic (4.87e-2)" "unprognostic (2.69e-3)" "unprognostic (1.99e-1)" "unprognostic (1.11e-1)" "unprognostic (2.96e-1)" "unprognostic (6.47e-2)" "unprognostic (1.43e-2)" "unprognostic (2.39e-2)" "unprognostic (7.65e-2)" "unprognostic (1.71e-2)" "unprognostic (1.15e-2)" "unprognostic (3.33e-2)" "unprognostic (6.67e-4)" "unprognostic (1.88e-2)" "unprognostic (6.80e-2)" "unprognostic (4.25e-1)" "unprognostic (2.84e-2)" 53.8 77.8 82.0 34.9 87.3 31.7 48.6 88.9 90.2 40.9 76.0 55.1 71.8 36.9 27.5 59.4 44.4 41.2 195.5 78.2 87.4 141.7 239.9 34.5 53.8 89.0 86.3 66.6 52.7 61.9 54.8 40.2 90.2 43.9 57.5 32.2 60.1 33.4 208.0 40.6 51.3 32.4 83.9 48.2 50.1 33.0 89.9 35.9 55.1 225.6 28.1 40.0 41.1 85.5 55.8 52.7 57.1 98.7 42.8 38.3 23.7 0.0 4.5 1.9 2.9 7.0 54.8 2.6 61.9 62.9 51.7 38.8 77.2 34.7 1.1 36.8 32.8 217.2 60.1 47.6 41.7 94.8 39.7 80.4 69.6 28.3 57.1 39.5 64.4 66.1 86.6 51.2 34.9 118.5 94.4 103.6 110.9 150.0 80.5 190.1 43.1 223.3 72.4 49.8 48.5 96.4 76.7 138.9 52.0 28.4 146.2 131.4 19.7 27.7 39.0 2.5 33.7 80.7 79.2 37.6 64.9 192.0 20.7 87.3 110.4 60.4 102.2 123.5 101.4 153.3 129.7 107.0 147.7 167.1 124.6 95.2 21.7 136.1 167.7 96.3 145.3 190.3 82.0 87.3 88.9 90.2 78.2 87.4 89.0 86.3 90.2 83.9 89.9 85.5 0.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.6 1.1 0.0 0.0 0.0 0.0 0.0 2.9 1.4 0.0 17.6 6.9 0.0 1.1 1.9 0.7 0.0 0.0 0.0 5.0 3.2 0.3 0.0 2.0 0.0 0.5 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 7.8 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.7 0.0 0.0 31.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 3.4 0.7 1.9 0.0 0.0 GFM1 "EFGM, EGF1, GFM, mtEF-G1" ENSG00000168827 "G elongation factor mitochondrial 1" Q96RP9 3 158644527-158695581 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Protein biosynthesis" "Elongation factor" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034764, HPA034765, HPA061405" Enhanced Approved Nucleoplasm,Mitochondria NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria Nucleoplasm "HPA034764: AB_2674320, HPA034765: AB_10669849, HPA061405: AB_2684505" "unprognostic (1.26e-1)" "unprognostic (1.61e-1)" "unprognostic (5.48e-3)" "unprognostic (4.48e-3)" "unprognostic (1.84e-1)" "unprognostic (3.40e-1)" "unprognostic (4.75e-2)" "unprognostic (6.05e-2)" "unprognostic (2.48e-1)" "unprognostic (8.36e-2)" "prognostic unfavorable (9.20e-4)" "unprognostic (2.79e-1)" "prognostic favorable (1.16e-7)" "unprognostic (1.62e-1)" "unprognostic (4.78e-1)" "unprognostic (3.32e-2)" "unprognostic (8.78e-2)" 26.7 25.0 12.3 21.7 13.2 24.1 27.8 18.1 21.3 14.1 16.8 30.1 24.9 17.2 20.8 24.1 13.4 17.5 39.0 13.0 15.5 43.7 49.6 18.8 20.7 14.5 13.2 12.7 26.4 40.1 12.0 25.7 15.3 19.6 31.5 46.4 21.0 21.9 63.0 15.2 19.8 20.9 13.7 16.4 23.9 23.5 14.1 16.6 32.1 60.2 20.7 23.5 12.9 15.7 92.2 55.9 25.5 32.0 41.8 30.6 34.2 42.6 49.8 75.9 57.4 73.2 58.7 73.9 54.7 39.2 32.0 55.9 62.5 47.8 84.3 40.6 33.7 56.1 34.6 34.3 48.6 76.7 35.9 37.3 55.7 43.8 41.0 17.6 50.2 43.0 71.7 50.3 67.9 56.9 49.6 30.6 55.7 97.0 29.8 49.8 28.0 132.6 51.0 38.3 48.9 42.8 63.8 96.1 79.1 19.9 132.1 60.0 28.0 46.4 21.0 69.4 74.1 82.7 61.4 138.9 41.8 65.0 52.4 18.9 19.3 13.8 22.2 27.2 28.6 17.0 19.3 23.0 23.3 16.4 22.1 23.9 3.0 25.4 22.0 11.2 17.4 18.4 12.3 13.2 18.1 21.3 13.0 15.5 14.5 13.2 15.3 13.7 14.1 15.7 31.4 19.2 19.0 17.0 26.1 21.5 26.0 20.9 20.5 57.3 23.0 11.9 54.8 22.8 18.9 12.9 31.3 31.6 20.1 22.2 11.7 19.9 15.4 12.4 20.2 36.6 19.3 29.0 39.8 25.0 17.6 20.9 22.4 14.8 19.0 17.7 22.5 61.6 29.0 15.2 43.9 24.5 30.5 20.4 21.5 7.6 22.7 21.7 17.8 18.7 33.8 27.3 16.5 22.6 43.3 20.3 10.5 17.0 19.2 21.7 22.1 37.9 25.1 51.6 13.1 21.5 23.4 34.4 31.6 20.1 21.0 30.8 22.3 41.4 28.9 22.0 GFM2 "EF-G2mt, EFG2, FLJ21661" ENSG00000164347 "GTP dependent ribosome recycling factor mitochondrial 2" Q969S9 5 74721206-74767147 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Protein biosynthesis" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Respiratory ciliated cells: 61.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036863, HPA069871" Uncertain Approved "Nucleoplasm,Midbody ring,Mitochondria" Yes NA "Cluster 11: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 49: Ciliated cells - Cilium organization" Mitochondria "Nucleoplasm, Midbody ring" "HPA036863: AB_2675354, HPA069871: " "unprognostic (2.58e-3)" "unprognostic (7.04e-2)" "unprognostic (8.54e-3)" "unprognostic (1.98e-1)" "unprognostic (4.49e-2)" "unprognostic (2.05e-2)" "unprognostic (1.73e-1)" "unprognostic (1.64e-1)" "unprognostic (1.40e-1)" "unprognostic (3.80e-2)" "unprognostic (2.10e-2)" "unprognostic (1.29e-1)" "prognostic favorable (1.33e-5)" "unprognostic (9.55e-2)" "unprognostic (4.15e-1)" "unprognostic (8.52e-3)" "unprognostic (9.82e-2)" 9.6 18.1 9.7 10.2 10.5 15.0 14.1 10.2 14.5 10.7 16.1 13.9 9.3 11.1 17.4 11.9 23.4 9.0 33.3 10.8 10.7 23.3 34.0 9.0 12.2 9.5 9.1 11.4 10.0 30.4 10.7 13.5 10.0 13.0 15.8 16.8 13.4 11.2 30.6 11.3 10.8 10.8 9.4 8.5 17.9 15.8 10.2 17.2 13.1 38.5 15.5 12.9 7.0 11.1 39.5 34.3 27.2 52.2 20.3 27.1 28.2 41.5 24.7 41.5 44.1 36.4 24.9 39.7 44.9 21.9 65.7 32.1 55.0 59.6 54.8 34.8 35.5 22.9 31.7 27.0 27.1 23.6 26.0 32.1 26.3 33.6 40.5 29.8 30.3 39.4 40.7 32.9 48.5 23.3 32.1 15.1 11.4 14.8 29.7 41.1 43.5 49.3 32.0 24.7 46.6 24.8 46.3 38.1 44.3 30.1 33.0 44.0 24.0 16.2 27.8 20.5 27.2 19.0 38.3 40.1 24.1 34.2 24.6 22.8 6.9 9.2 6.7 7.2 6.6 8.3 5.5 7.5 6.7 7.2 7.5 7.3 3.5 16.0 11.8 4.4 7.0 5.2 9.7 10.5 10.2 14.5 10.8 10.7 9.5 9.1 10.0 9.4 10.2 11.1 6.4 12.8 12.9 19.9 8.5 6.0 7.1 13.0 8.6 9.1 7.7 6.9 11.0 7.2 12.5 7.3 6.2 20.1 7.5 8.9 21.5 9.5 11.5 42.4 9.2 6.4 5.4 17.9 35.7 5.3 15.9 6.3 15.3 13.7 2.5 10.4 5.3 22.4 9.9 16.8 34.1 9.7 30.5 8.5 2.4 2.6 7.2 6.8 8.8 13.1 17.9 13.0 7.2 34.2 29.1 9.8 9.9 7.5 11.4 4.6 8.5 11.2 61.5 9.6 0.0 5.6 7.8 15.2 11.7 10.0 7.0 16.0 7.3 11.1 10.0 7.5 GIT1 ENSG00000108262 "GIT ArfGAP 1" Q9Y2X7 17 29573475-29594054 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 122.3" "Cell type enhanced" "Detected in all" "Early spermatids: 97.8;Late spermatids: 99.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004059, HPA004186" Enhanced Supported "Focal adhesion sites,Mitochondria,Cytosol" NA NA 36000 "Cluster 15: NK-cells - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 34: Spermatids - Unknown function" "Focal adhesion sites, Cytosol" Mitochondria "HPA004059: AB_1078966, HPA004186: AB_1078967" "unprognostic (3.66e-1)" "unprognostic (4.46e-2)" "unprognostic (3.24e-2)" "unprognostic (6.30e-3)" "unprognostic (1.46e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (2.54e-6)" "unprognostic (3.00e-3)" "unprognostic (2.79e-1)" "unprognostic (5.23e-2)" "unprognostic (2.12e-2)" "unprognostic (3.08e-1)" "unprognostic (8.48e-2)" "unprognostic (5.56e-2)" "unprognostic (7.30e-2)" "unprognostic (2.10e-1)" "unprognostic (1.69e-1)" 30.2 13.5 79.4 18.0 89.3 14.4 29.9 29.1 122.3 22.0 14.9 20.5 17.9 20.9 7.6 28.6 22.5 15.5 28.9 101.2 38.0 18.4 7.6 34.8 21.3 42.5 45.3 21.3 21.9 18.0 23.7 21.1 39.7 21.3 10.1 12.1 19.0 14.4 31.9 34.2 20.5 12.9 31.7 22.3 19.1 88.8 51.8 23.1 23.2 18.5 15.2 21.6 23.6 62.1 49.7 80.9 39.1 69.9 30.4 19.1 45.3 23.9 23.4 28.2 25.1 33.1 18.0 37.3 37.3 31.5 50.5 79.5 41.6 61.4 14.4 48.3 49.7 26.9 39.8 29.8 37.0 34.4 21.3 23.4 69.2 32.4 50.5 40.0 53.0 48.6 22.3 31.2 20.5 50.9 109.0 45.7 29.2 49.9 19.2 81.7 52.3 55.6 25.8 26.7 82.0 70.0 33.8 77.2 117.7 27.9 38.0 45.0 66.2 26.7 38.2 59.3 49.0 25.8 39.3 41.5 43.9 29.0 45.9 0.1 1.6 1.4 1.9 2.5 0.9 0.7 1.9 2.1 2.2 0.6 1.6 1.1 0.5 2.4 1.8 1.8 1.3 1.8 79.4 89.3 29.1 122.3 101.2 38.0 42.5 45.3 39.7 31.7 51.8 62.1 54.6 3.2 1.5 21.9 9.5 27.1 6.7 9.2 10.2 15.5 12.6 16.3 8.7 4.3 4.9 5.5 10.4 5.1 17.3 19.2 1.9 7.5 97.8 9.4 16.8 30.8 14.9 1.7 16.8 9.4 8.0 9.7 11.2 10.5 1.3 17.9 22.5 4.0 8.3 11.8 14.1 13.8 8.2 9.5 18.9 99.2 14.3 10.6 8.8 15.9 7.4 13.3 9.2 12.5 16.9 9.5 11.5 10.5 8.7 13.4 17.2 6.1 9.8 10.2 13.1 17.3 9.5 30.5 11.5 14.4 28.1 3.6 12.4 8.6 14.6 8.3 GJB2 "CX26, DFNA3, DFNB1, NSRD1" ENSG00000165474 "Gap junction protein beta 2" P29033 13 20187463-20192938 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Hearing "Deafness, Disease variant, Ectodermal dysplasia, Ichthyosis, Non-syndromic deafness, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 328.1;esophagus: 812.1;vagina: 519.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 69.8;Basal respiratory cells: 237.4;Basal squamous epithelial cells: 55.8;Ionocytes: 50.8;Squamous epithelial cells: 160.9" "Cancer enhanced" "Detected in all" "head and neck cancer: 447.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "CAPAN-2: 144.6;hTCEpi: 105.4;OE19: 76.9;RT4: 169.9" "Low region specificity" "Detected in all" "CAB013093, HPA014362" Uncertain Approved Mitochondria NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Mitochondria "CAB013093: AB_2533903, HPA014362: " "unprognostic (2.21e-1)" "unprognostic (1.25e-3)" "unprognostic (2.43e-2)" "unprognostic (6.14e-2)" "prognostic unfavorable (4.45e-4)" "unprognostic (9.77e-2)" "unprognostic (2.92e-1)" "prognostic unfavorable (6.25e-4)" "unprognostic (1.33e-1)" "unprognostic (3.69e-3)" "prognostic unfavorable (2.90e-4)" "unprognostic (3.22e-2)" "prognostic unfavorable (2.53e-6)" "unprognostic (5.78e-3)" "unprognostic (2.40e-1)" "unprognostic (1.17e-2)" "unprognostic (8.93e-3)" 2.0 0.7 1.3 6.7 1.2 3.8 3.7 2.4 3.1 328.1 5.3 20.8 12.9 2.9 3.4 812.1 0.9 14.0 0.4 1.1 1.7 9.8 47.5 0.7 0.4 1.8 1.7 0.3 1.3 0.1 4.1 0.2 1.7 1.2 17.4 0.0 145.2 0.3 0.4 73.0 10.6 2.6 1.7 0.2 8.1 1.2 7.6 12.5 1.7 1.2 90.4 27.9 519.8 1.6 8.7 0.6 0.0 0.2 0.0 2.9 1.7 0.0 0.0 0.0 0.0 1.3 144.6 0.0 0.7 0.1 1.1 28.9 5.3 14.4 0.1 12.6 1.8 0.1 0.1 0.3 0.0 0.0 5.1 2.4 105.4 1.9 19.5 0.0 0.0 2.1 0.1 10.7 0.2 1.4 1.3 0.0 0.3 76.9 14.4 0.2 0.0 8.3 0.2 169.9 0.1 0.0 0.3 0.1 0.3 1.9 2.2 0.4 0.0 0.2 0.0 2.5 22.2 8.7 9.6 0.0 17.1 0.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.2 2.4 3.1 1.1 1.7 1.8 1.7 1.7 1.7 7.6 1.6 0.1 3.2 0.0 2.0 0.6 69.8 16.1 237.4 55.8 0.0 1.3 1.3 0.5 4.3 37.3 1.8 0.0 0.1 0.0 28.0 0.0 4.4 1.5 5.0 1.5 1.3 4.2 0.0 0.0 9.8 0.2 1.7 4.1 19.1 0.0 0.0 0.0 25.2 0.6 0.0 0.0 6.1 50.8 0.6 13.3 1.3 0.0 3.9 1.8 0.0 4.6 0.0 0.0 0.0 0.0 9.2 13.3 0.0 2.7 8.6 10.7 17.5 7.5 0.0 0.0 0.1 4.7 0.8 2.1 160.9 28.7 0.1 0.9 0.0 25.0 21.7 GLCE "HSEPI, KIAA0836" ENSG00000138604 "Glucuronic acid epimerase" O94923 15 69160584-69272217 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 79.0;Microglial cells: 76.8;Oligodendrocytes: 154.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 35.8" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 8 "dendritic cells: 1.9;monocytes: 2.3;T-cells: 2.0" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 119.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040481, HPA048216" Uncertain Approved Mitochondria "Intracellular and membrane" NA NA 240000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA040481: AB_2677004, HPA048216: AB_2680317" "unprognostic (1.30e-1)" "unprognostic (2.39e-1)" "unprognostic (1.20e-3)" "unprognostic (7.77e-2)" "unprognostic (1.58e-1)" "unprognostic (5.55e-3)" "unprognostic (1.00e-1)" "unprognostic (2.84e-1)" "unprognostic (1.48e-1)" "unprognostic (2.56e-1)" "unprognostic (7.47e-2)" "unprognostic (1.41e-1)" "unprognostic (2.40e-2)" "unprognostic (1.53e-1)" "unprognostic (6.00e-2)" "unprognostic (5.23e-1)" "unprognostic (4.07e-2)" 9.1 12.2 6.7 5.6 7.8 0.9 8.9 35.8 6.2 8.2 8.4 12.8 14.2 6.4 6.9 10.0 5.5 7.5 6.3 6.0 6.7 13.3 16.8 8.4 3.5 5.7 8.5 12.7 4.7 8.7 6.4 13.4 7.2 5.8 14.2 13.2 10.9 5.8 4.1 10.4 11.5 7.0 7.5 4.4 9.1 3.9 8.8 4.9 4.1 4.9 5.1 6.6 4.6 8.0 9.6 8.5 5.6 9.7 18.6 17.6 2.0 17.6 23.2 13.3 25.2 7.1 23.6 5.8 8.5 14.4 16.8 14.0 12.1 11.4 27.1 2.2 13.4 9.7 15.0 7.2 17.9 4.2 19.0 12.1 7.8 16.6 18.6 9.7 119.4 4.3 3.9 6.0 25.4 5.9 2.6 7.4 2.7 9.7 5.9 5.8 22.6 7.3 12.3 10.1 17.9 3.7 18.0 11.0 38.1 3.8 7.9 5.8 41.8 12.7 15.7 14.3 15.8 2.5 3.7 1.3 12.9 7.0 18.8 0.0 2.1 0.0 0.3 1.6 0.5 0.2 0.8 0.4 1.8 0.2 0.5 0.7 0.0 0.2 2.3 1.9 2.0 0.9 6.7 7.8 35.8 6.2 6.0 6.7 5.7 8.5 7.2 7.5 8.8 8.0 16.9 0.0 15.4 4.9 6.2 4.8 10.1 8.3 26.2 10.3 18.8 19.4 8.1 7.2 8.8 11.0 10.4 22.7 12.1 21.3 5.9 13.0 3.9 4.0 5.4 22.6 20.4 9.4 79.0 13.8 12.7 14.0 28.1 4.9 2.5 11.8 16.4 27.2 16.4 8.4 41.5 27.1 10.2 13.3 4.4 5.1 6.2 10.7 8.8 76.8 13.7 13.1 4.1 35.7 154.9 16.9 28.2 17.7 7.1 5.3 32.4 18.3 18.2 16.6 13.1 6.6 9.4 29.8 25.9 27.9 6.5 33.0 5.9 17.1 26.4 13.3 GLIS1 FLJ36155 ENSG00000174332 "GLIS family zinc finger 1" Q8NBF1 1 53506237-53738106 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 8.1;seminal vesicle: 7.6" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 6.6;Excitatory neurons: 28.0;Inhibitory neurons: 13.3;Proximal tubular cells: 4.8" "Cancer enhanced" "Detected in some" "renal cancer: 4.0" "Region enhanced" "Detected in some" "cerebral cortex: 2.2;hippocampal formation: 2.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 4.5;GAMG: 5.9;hTERT-RPE1: 4.7;PC-3: 7.3;U-138 MG: 5.1" "Not detected" "Not detected" HPA001409 Uncertain Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Mitochondria, Cytosol" "HPA001409: AB_1078974" "unprognostic (1.30e-1)" "unprognostic (1.46e-1)" "unprognostic (2.07e-1)" "unprognostic (5.31e-2)" "unprognostic (3.67e-2)" "unprognostic (1.54e-2)" "unprognostic (8.91e-3)" "unprognostic (1.92e-1)" "unprognostic (2.27e-3)" "unprognostic (2.30e-1)" "unprognostic (3.03e-2)" "unprognostic (1.15e-2)" "unprognostic (1.93e-1)" "unprognostic (4.06e-2)" "unprognostic (1.55e-1)" "unprognostic (6.37e-4)" "unprognostic (1.98e-4)" 1.0 0.1 0.5 0.4 0.5 0.0 1.2 0.2 2.2 5.1 0.0 0.3 0.3 0.9 0.5 0.8 0.8 0.6 1.0 2.2 0.0 4.3 0.0 0.2 0.1 0.1 0.1 0.6 0.0 0.1 0.1 0.0 0.0 8.1 0.0 0.0 0.8 7.6 0.1 2.0 0.6 0.2 0.1 0.2 0.8 2.3 0.0 0.2 0.4 0.0 0.0 2.6 4.6 0.3 0.0 0.0 0.0 0.4 2.8 3.7 0.0 2.0 4.5 1.7 1.3 0.0 0.0 0.0 0.1 2.1 5.9 0.0 0.0 0.0 0.5 0.0 1.3 0.0 1.4 0.1 1.0 0.0 0.0 2.5 0.2 2.1 2.0 4.7 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 7.3 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.9 0.1 1.3 0.0 0.0 3.1 0.4 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.2 2.2 2.2 0.0 0.1 0.1 0.0 0.1 0.0 0.3 0.2 0.0 0.0 1.3 0.1 6.6 0.0 0.0 4.0 1.3 0.1 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.2 0.1 0.0 0.0 28.0 0.0 0.0 3.8 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 13.3 0.0 0.0 0.0 1.0 2.9 0.3 0.0 3.6 1.0 0.0 0.0 0.0 0.5 1.5 0.0 0.0 1.2 0.1 0.1 0.0 4.8 0.0 0.0 0.0 0.4 0.8 1.8 2.8 0.3 1.7 0.1 0.1 0.1 0.0 0.1 GLT8D1 "AD-017, FLJ14611" ENSG00000016864 "Glycosyltransferase 8 domain containing 1" Q68CQ7 3 52694486-52706032 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 149.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010588 Approved Approved Mitochondria NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 23: Testis - Cell cycle regulation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "HPA010588: AB_1078098" "unprognostic (1.37e-1)" "unprognostic (2.96e-1)" "unprognostic (1.38e-2)" "prognostic favorable (2.76e-4)" "unprognostic (3.17e-2)" "unprognostic (1.55e-1)" "unprognostic (2.03e-1)" "unprognostic (1.82e-3)" "unprognostic (7.12e-2)" "unprognostic (9.81e-2)" "unprognostic (1.23e-1)" "unprognostic (1.07e-1)" "unprognostic (5.82e-3)" "unprognostic (2.42e-3)" "unprognostic (3.97e-1)" "unprognostic (3.34e-2)" "unprognostic (6.21e-2)" 33.1 39.8 25.4 22.5 26.6 9.3 35.6 25.2 29.3 47.5 35.6 27.7 25.9 35.0 41.3 18.3 54.4 29.8 32.6 26.2 26.7 40.4 69.5 29.6 25.3 24.0 26.9 53.8 35.7 46.0 64.8 48.2 25.5 30.5 32.3 32.2 29.9 32.7 20.8 22.6 23.4 32.2 25.9 24.6 28.9 64.5 26.4 29.2 64.0 24.6 26.8 31.6 28.6 28.6 28.7 33.2 65.7 52.0 142.6 179.8 36.8 70.3 107.8 60.6 69.1 15.5 52.6 24.0 19.7 122.7 73.3 31.9 42.1 72.0 79.5 43.5 30.6 22.8 61.4 71.7 68.3 34.0 68.5 104.1 62.9 52.1 66.8 139.8 91.3 40.6 29.4 53.6 80.6 29.2 23.4 51.8 33.8 49.8 61.5 17.4 37.3 81.9 71.3 30.8 26.9 46.5 58.6 27.9 48.9 61.2 47.7 44.2 67.1 43.7 33.9 63.9 39.6 60.2 73.7 26.4 76.0 53.2 56.2 38.4 13.0 21.8 19.1 8.5 18.3 14.1 22.2 20.0 11.8 9.8 22.3 15.6 6.9 30.3 9.3 23.1 16.8 10.9 25.4 26.6 25.2 29.3 26.2 26.7 24.0 26.9 25.5 25.9 26.4 28.6 25.8 0.0 9.6 16.0 16.0 12.1 16.1 40.3 13.6 41.5 18.1 19.7 15.3 17.2 23.8 18.4 12.5 58.4 26.5 9.4 23.5 34.4 71.4 38.5 38.4 22.7 18.6 8.6 17.9 27.1 63.5 59.2 14.8 15.2 5.7 35.6 34.2 38.2 26.9 21.9 16.8 21.1 30.5 13.6 12.0 23.0 53.7 12.3 24.9 8.4 26.5 37.0 34.0 15.6 14.6 23.3 16.9 48.5 39.1 14.7 22.8 21.5 44.4 21.3 26.3 31.6 25.2 149.5 50.0 10.3 8.0 26.1 21.4 74.2 17.3 10.0 GLUD2 GLUDP1 ENSG00000182890 "Glutamate dehydrogenase 2" P49448 X 121047610-121050094 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "liver: 3.9;testis: 15.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.6;Cytotrophoblasts: 4.6;Early spermatids: 2.6;Hepatocytes: 4.6;Proximal tubular cells: 3.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 3.7;K-562: 4.3;OE19: 2.1;SK-MEL-30: 5.5;THP-1: 2.7;WM-115: 6.0" "HPA042492, HPA044839, HPA061369" Uncertain Approved Mitochondria NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA042492: AB_2678024, HPA044839: AB_2679107, HPA061369: AB_2684494" "unprognostic (1.44e-1)" "unprognostic (5.49e-2)" "unprognostic (1.90e-2)" "unprognostic (1.39e-2)" "unprognostic (1.27e-3)" "unprognostic (1.29e-1)" "unprognostic (1.77e-2)" "unprognostic (1.24e-1)" "unprognostic (2.23e-1)" "unprognostic (2.42e-1)" "unprognostic (2.61e-1)" "unprognostic (2.35e-1)" "prognostic favorable (1.98e-4)" "unprognostic (1.04e-2)" "unprognostic (1.49e-2)" "unprognostic (4.77e-3)" "unprognostic (5.96e-2)" 1.7 1.7 0.0 0.1 0.3 0.0 1.2 0.0 0.8 0.4 0.5 0.5 0.0 0.4 1.7 0.5 0.4 0.4 0.9 0.4 0.0 1.6 3.9 0.5 0.1 0.0 0.0 0.4 1.0 0.5 0.4 0.8 0.0 0.4 0.0 0.1 0.6 0.2 0.5 0.6 0.4 0.1 0.0 0.1 0.6 15.4 0.1 0.0 0.4 0.1 0.1 0.4 0.4 0.1 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.5 0.0 0.3 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.8 0.0 0.0 0.7 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 5.5 0.1 1.2 2.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.8 0.0 0.0 2.3 0.1 0.0 0.5 0.0 0.6 0.0 0.4 0.1 2.6 0.0 0.0 0.0 2.1 4.6 0.1 0.1 1.9 0.2 2.6 0.6 0.8 0.9 0.0 0.0 1.2 0.4 0.5 0.8 0.0 0.5 0.0 0.1 0.0 4.6 0.5 0.0 0.4 0.1 0.0 1.2 0.3 2.2 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.4 0.2 3.3 0.0 0.1 0.0 0.9 0.4 1.2 1.0 0.1 0.1 2.5 0.3 0.7 0.2 0.3 GLYATL2 "BXMAS2-10, MGC24009" ENSG00000156689 "Glycine-N-acyltransferase like 2" Q8WU03 11 58834065-58904215 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 12.0;cervix: 19.9;salivary gland: 33.4" "Cell type enhanced" "Detected in some" "Breast glandular cells: 14.8;Oligodendrocyte precursor cells: 3.0;Prostatic glandular cells: 3.6;Sertoli cells: 6.6" "Group enriched" "Detected in many" 4 "breast cancer: 16.7;endometrial cancer: 15.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 5.3;BJ hTERT+ SV40 Large T+ RasG12V: 3.7;HAP1: 6.0;SK-BR-3: 14.1;U-2197: 6.6" "Low region specificity" "Detected in many" "HPA060292, HPA065454" Uncertain Approved Mitochondria NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 35: Glandular cells - Unknown function" Mitochondria "HPA060292: AB_2684245, HPA065454: " "unprognostic (1.02e-2)" "unprognostic (3.79e-3)" "unprognostic (8.11e-4)" "prognostic favorable (9.05e-7)" "unprognostic (1.05e-1)" "unprognostic (8.41e-2)" "unprognostic (2.66e-2)" "unprognostic (9.98e-3)" "unprognostic (1.27e-1)" "unprognostic (9.18e-3)" "unprognostic (1.64e-1)" "unprognostic (1.59e-1)" "unprognostic (7.42e-5)" "unprognostic (7.79e-3)" "unprognostic (8.28e-2)" "unprognostic (9.11e-3)" "unprognostic (2.31e-2)" 0.2 0.1 0.2 0.1 0.3 0.1 12.0 0.2 0.5 19.9 0.0 0.1 0.3 0.4 0.3 0.9 0.1 7.5 0.3 0.2 0.4 0.9 0.1 0.0 0.3 0.7 0.2 0.0 0.1 0.0 0.1 0.0 0.6 0.9 0.2 0.3 33.4 0.1 0.0 1.4 0.1 0.3 0.7 0.3 0.1 0.0 0.2 0.1 0.1 0.5 0.4 0.1 0.3 1.1 0.0 0.0 0.4 0.0 0.7 2.6 0.0 1.7 5.3 2.3 3.7 0.0 0.0 0.1 0.0 1.4 1.0 0.4 6.0 0.0 1.9 0.0 1.1 0.0 0.0 0.0 0.2 0.0 0.2 0.5 0.0 0.5 0.2 2.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.1 14.1 0.0 0.0 0.0 0.0 0.0 1.8 0.1 6.6 2.0 0.0 0.0 0.1 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.2 0.5 0.2 0.4 0.7 0.2 0.6 0.7 0.2 1.1 0.2 0.0 0.0 0.0 0.0 1.0 2.3 1.4 0.0 0.5 14.8 2.2 0.1 0.0 1.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.4 1.1 0.0 0.0 1.5 1.4 0.0 0.5 0.0 1.2 0.0 0.4 0.0 0.0 0.1 0.0 1.5 0.0 0.0 0.0 0.4 0.0 0.0 0.3 1.8 0.0 0.0 0.0 0.0 3.0 0.4 0.1 0.0 0.0 0.0 3.6 0.0 0.2 0.1 0.1 6.6 0.2 0.6 0.0 0.1 0.0 2.0 0.0 0.0 0.0 0.0 1.9 GNG12 ENSG00000172380 "G protein subunit gamma 12" Q9UBI6 1 67701475-67833467 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 243.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA057790, HPA062208" Enhanced Supported Approved Mitochondria NA NA 550000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA057790: AB_2683527, HPA062208: AB_2684711" "unprognostic (5.18e-2)" "unprognostic (1.76e-3)" "unprognostic (4.46e-3)" "unprognostic (7.77e-2)" "unprognostic (1.06e-1)" "unprognostic (4.71e-2)" "unprognostic (5.29e-2)" "unprognostic (5.84e-3)" "unprognostic (5.50e-2)" "unprognostic (3.41e-2)" "unprognostic (4.46e-3)" "unprognostic (8.13e-2)" "unprognostic (4.12e-3)" "unprognostic (2.33e-2)" "unprognostic (9.33e-2)" "unprognostic (7.78e-2)" "unprognostic (2.14e-3)" 63.4 57.0 14.4 28.5 12.3 0.3 50.1 10.4 14.0 59.3 13.5 68.4 122.0 59.7 27.7 82.0 43.4 59.3 34.5 13.7 19.5 79.2 44.8 34.3 12.0 21.9 29.1 47.9 25.2 54.7 13.1 60.2 16.9 38.3 65.7 6.6 26.6 47.6 12.9 80.4 110.8 73.9 18.6 56.2 42.7 17.7 16.4 15.9 59.8 19.7 22.7 56.5 46.5 18.7 60.5 55.5 58.0 31.5 241.2 207.9 59.5 182.9 237.2 157.9 141.0 26.5 58.2 0.1 75.9 258.0 98.8 44.2 36.6 150.0 275.7 0.5 28.1 1.0 46.0 0.1 96.0 0.1 3.0 125.7 87.8 168.7 221.8 221.1 251.9 0.0 3.6 0.3 175.6 10.2 0.1 0.5 44.1 65.7 68.3 0.3 119.6 0.9 151.8 53.5 13.2 26.8 126.8 52.1 248.4 48.8 26.9 1.1 326.7 182.5 118.8 332.0 114.5 3.0 0.3 0.5 115.3 7.1 252.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.4 12.3 10.4 14.0 13.7 19.5 21.9 29.1 16.9 18.6 16.4 18.7 49.7 54.5 32.2 54.5 2.1 201.3 78.8 53.3 78.6 2.1 52.4 37.1 26.7 35.8 42.8 58.8 6.2 61.8 0.9 243.1 74.3 96.2 14.6 51.8 20.6 67.0 34.7 5.3 0.5 138.5 105.6 82.6 45.3 49.3 3.8 21.3 76.1 45.6 27.9 3.3 15.3 56.3 30.5 18.2 32.4 16.6 71.4 6.2 78.2 21.5 3.6 3.0 0.0 63.3 1.3 143.7 99.9 75.6 0.2 119.9 227.3 177.9 79.2 18.9 52.6 54.8 71.7 1.8 18.8 83.1 216.8 175.9 4.5 107.1 61.8 109.1 GPAM "GPAT1, KIAA1560, MGC26846" ENSG00000119927 "Glycerol-3-phosphate acyltransferase, mitochondrial" Q9HCL2 10 112149865-112215377 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 305.7;liver: 144.1" "Cell type enhanced" "Detected in many" "Astrocytes: 90.8;Hepatocytes: 184.5;Horizontal cells: 45.4" "Cancer enriched" "Detected in all" 5 "liver cancer: 20.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "ASC diff: 250.3;Hep G2: 71.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046339, HPA060090" Approved Approved Mitochondria NA NA "Cluster 24: B-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Mitochondria "HPA046339: AB_2679627, HPA060090: AB_2684202" "unprognostic (1.82e-1)" "unprognostic (6.28e-2)" "unprognostic (1.13e-1)" "unprognostic (1.30e-1)" "unprognostic (6.80e-2)" "unprognostic (8.75e-2)" "unprognostic (1.40e-2)" "unprognostic (2.16e-2)" "unprognostic (4.59e-1)" "unprognostic (4.80e-1)" "unprognostic (2.37e-2)" "unprognostic (5.44e-2)" "prognostic favorable (4.54e-6)" "unprognostic (2.84e-1)" "unprognostic (4.41e-2)" "unprognostic (2.52e-2)" "unprognostic (1.37e-1)" 305.7 33.9 14.9 4.8 17.1 3.4 67.7 12.2 14.0 3.0 6.9 6.4 4.0 4.2 75.1 2.9 3.1 6.0 12.3 12.4 13.0 4.4 144.1 4.1 4.6 12.9 16.0 5.3 5.0 4.3 2.1 3.0 12.1 3.9 4.7 5.1 17.2 5.3 8.3 3.2 6.1 4.9 11.5 2.9 4.9 5.6 15.7 3.6 12.4 8.8 4.3 4.8 2.6 10.5 9.9 7.4 9.7 12.9 250.3 9.1 12.7 9.2 10.5 6.6 5.1 17.3 5.7 6.9 5.0 6.5 6.1 12.3 15.5 7.9 12.3 5.0 8.4 6.4 7.9 71.8 7.7 11.2 3.4 43.8 13.1 11.7 23.6 49.7 5.8 9.7 8.5 6.1 7.7 5.6 9.6 8.8 8.1 5.6 10.1 9.7 25.4 5.1 4.3 6.8 4.1 12.1 12.8 6.1 14.5 8.9 6.3 4.0 4.4 7.5 4.6 9.4 14.8 6.1 7.3 14.3 8.8 9.8 5.8 0.0 0.3 0.1 0.7 0.4 0.9 0.5 0.5 0.5 0.4 1.1 0.5 0.9 0.0 0.3 0.3 0.6 0.6 0.3 14.9 17.1 12.2 14.0 12.4 13.0 12.9 16.0 12.1 11.5 15.7 10.5 9.1 9.6 27.1 90.8 5.2 0.4 0.8 1.6 4.6 5.3 8.1 8.4 18.9 20.0 4.3 5.5 10.4 5.2 4.3 1.7 1.9 2.7 0.5 5.1 10.0 5.0 1.2 12.2 8.2 3.3 2.9 5.1 3.6 4.2 2.5 12.7 6.4 184.5 3.1 45.4 9.4 3.0 0.0 9.3 1.0 0.9 5.3 1.9 1.8 10.3 1.4 6.1 3.1 10.1 10.1 3.4 2.7 12.0 6.4 1.1 3.7 3.3 4.7 9.1 6.6 4.3 6.6 4.0 3.2 5.4 0.1 1.9 3.3 8.6 5.0 0.6 GPAT2 CT123 ENSG00000186281 "Glycerol-3-phosphate acyltransferase 2, mitochondrial" Q6NUI2 2 96021946-96039451 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Breast glandular cells: 84.5;Sertoli cells: 98.6;Smooth muscle cells: 30.3;Spermatocytes: 64.4;Spermatogonia: 45.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BJ: 8.2;BJ hTERT+ SV40 Large T+: 19.6;BJ hTERT+ SV40 Large T+ RasG12V: 11.6;OE19: 13.9;U-2 OS: 10.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA036841 Uncertain Approved Mitochondria NA NA "Cluster 24: B-cells - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" Mitochondria "HPA036841: AB_10601479" "unprognostic (1.42e-2)" "unprognostic (2.39e-2)" "unprognostic (6.69e-2)" "unprognostic (3.83e-1)" "unprognostic (1.44e-1)" "unprognostic (2.38e-3)" "unprognostic (4.99e-2)" "unprognostic (3.28e-2)" "unprognostic (1.70e-1)" "unprognostic (1.44e-2)" "unprognostic (5.96e-2)" "unprognostic (4.67e-2)" "unprognostic (7.43e-6)" "unprognostic (2.11e-1)" "unprognostic (7.68e-2)" "unprognostic (3.49e-1)" "unprognostic (3.65e-1)" 5.8 0.8 1.5 1.4 1.7 1.2 4.5 1.4 1.7 2.4 3.3 1.8 0.2 1.5 3.1 0.8 1.6 1.6 7.4 1.2 1.3 1.6 1.0 1.3 2.4 1.7 1.6 1.2 1.6 0.1 0.6 1.4 2.0 1.1 1.0 0.2 2.2 2.8 2.1 1.1 2.2 1.6 1.3 4.6 2.1 7.6 2.4 0.8 1.7 3.0 1.9 2.0 1.4 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 8.2 0.0 19.6 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.4 0.0 2.8 0.0 0.0 0.3 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 1.0 0.7 1.0 1.6 0.5 0.7 0.4 2.4 0.3 1.1 0.0 0.1 1.0 0.0 0.5 0.6 1.5 1.7 1.4 1.7 1.2 1.3 1.7 1.6 2.0 1.3 2.4 2.1 12.9 0.0 1.1 0.3 3.5 1.0 1.1 0.7 0.6 0.7 84.5 3.4 1.3 1.5 0.5 1.8 0.0 0.1 1.7 3.1 1.9 2.2 1.9 0.1 0.5 6.5 0.0 0.8 1.0 2.0 0.6 3.3 1.5 0.5 1.3 0.2 10.8 0.0 2.4 8.4 0.4 0.6 0.0 0.8 2.1 5.3 0.6 1.5 1.8 1.9 0.7 1.0 1.0 0.0 1.4 0.8 1.3 0.0 3.6 0.4 0.0 0.2 0.2 0.4 98.6 3.2 30.3 64.4 45.3 0.4 0.1 0.1 2.2 0.3 2.1 1.8 GPATCH8 "GPATC8, KIAA0553" ENSG00000186566 "G-patch domain containing 8" Q9UKJ3 17 44395281-44503430 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Excitatory neurons: 312.1;Inhibitory neurons: 287.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044380 Approved Approved "Nuclear speckles,Mitochondria" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear speckles" Mitochondria "HPA044380: AB_10965696" "unprognostic (3.37e-1)" "unprognostic (5.90e-2)" "unprognostic (1.27e-1)" "unprognostic (1.37e-1)" "unprognostic (6.07e-3)" "unprognostic (2.13e-2)" "unprognostic (5.86e-3)" "unprognostic (2.25e-1)" "unprognostic (1.38e-1)" "unprognostic (6.84e-3)" "unprognostic (8.47e-2)" "unprognostic (6.99e-2)" "unprognostic (2.04e-2)" "unprognostic (1.50e-1)" "unprognostic (9.91e-2)" "unprognostic (7.58e-2)" "unprognostic (2.49e-1)" 10.5 9.2 12.0 11.3 13.3 18.3 11.0 15.0 14.0 10.6 9.3 8.9 11.1 14.5 11.8 9.4 11.1 8.8 8.9 11.8 12.5 9.0 7.0 10.7 15.7 12.9 12.9 17.3 8.0 14.4 0.4 13.1 12.7 9.5 10.4 30.1 9.3 10.2 33.4 15.5 11.0 12.5 12.1 13.1 8.8 10.8 13.0 20.8 11.0 13.8 15.4 9.8 0.8 13.5 22.0 12.8 22.8 18.9 17.5 20.2 23.1 16.7 21.1 18.3 19.2 19.0 13.9 31.1 10.9 23.7 15.8 16.7 23.3 19.3 27.2 25.7 20.8 26.5 15.5 22.5 20.9 25.7 20.3 22.9 20.5 20.9 27.2 18.4 20.2 19.4 20.1 18.7 16.8 10.0 33.7 9.9 16.0 12.5 16.2 27.1 25.8 21.7 16.0 10.6 15.9 19.3 16.6 10.6 20.9 27.0 13.9 17.3 22.5 18.0 12.6 19.3 23.4 20.1 17.9 29.2 16.8 14.1 19.3 8.2 6.1 4.9 9.4 6.0 8.7 8.6 8.2 7.8 6.5 7.1 7.5 7.3 4.6 10.3 13.6 8.0 4.1 5.2 12.0 13.3 15.0 14.0 11.8 12.5 12.9 12.9 12.7 12.1 13.0 13.5 38.8 22.4 32.5 148.5 64.6 48.7 53.1 52.0 47.8 72.7 28.8 22.7 40.5 30.0 46.0 25.8 123.0 42.4 76.6 25.2 9.8 32.8 19.6 38.7 63.3 38.8 38.8 50.1 312.1 24.5 39.3 48.4 23.9 56.5 42.4 44.6 44.3 19.4 23.0 146.4 287.3 20.3 36.7 36.2 42.3 7.6 63.0 38.6 23.2 108.7 42.5 43.5 161.7 172.9 204.1 34.7 24.7 43.2 58.1 45.3 30.2 14.6 29.8 125.3 52.6 68.6 51.2 93.1 74.2 33.7 46.9 53.4 69.8 43.1 25.4 56.8 GPN1 "ATPBD1A, MBDIN, NTPBP, RPAP4, XAB1" ENSG00000198522 "GPN-loop GTPase 1" Q9HCN4 2 27628247-27651511 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 86.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036793, HPA036794, CAB037303" Uncertain Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Cytosol" Mitochondria "CAB037303: AB_477173, HPA036793: AB_2675318, HPA036794: AB_10672230" "unprognostic (9.42e-2)" "unprognostic (1.44e-1)" "unprognostic (5.64e-2)" "prognostic unfavorable (2.88e-5)" "unprognostic (2.57e-1)" "unprognostic (1.63e-3)" "prognostic unfavorable (1.71e-5)" "unprognostic (3.50e-2)" "unprognostic (8.27e-3)" "unprognostic (8.93e-2)" "unprognostic (4.05e-3)" "unprognostic (2.34e-1)" "unprognostic (1.21e-2)" "unprognostic (2.51e-1)" "unprognostic (1.13e-1)" "unprognostic (2.01e-1)" "unprognostic (1.72e-1)" 22.8 22.8 19.3 20.3 19.8 34.1 26.4 19.9 26.1 18.1 19.5 22.7 19.9 19.1 19.9 25.5 21.0 18.6 21.3 19.4 21.6 26.3 24.6 18.6 28.7 22.5 22.6 18.4 22.8 25.9 16.6 26.5 21.8 17.7 25.6 24.9 21.5 16.9 32.4 24.8 19.6 22.4 19.6 22.2 20.6 25.5 21.9 30.1 22.8 27.2 30.3 24.0 19.5 21.2 94.6 53.3 48.8 35.4 44.3 44.8 48.7 52.0 50.5 70.7 52.1 58.0 47.4 58.8 49.2 56.4 65.4 39.5 67.6 63.4 71.5 55.4 47.6 66.8 38.3 70.7 57.3 100.0 33.7 46.7 54.8 72.6 67.1 49.4 75.2 51.5 84.7 53.5 84.1 54.2 60.3 75.1 83.4 70.9 50.7 60.2 144.4 61.0 57.9 53.5 42.9 67.6 57.2 61.5 58.4 44.7 37.1 56.0 62.9 61.5 91.1 30.9 122.7 60.8 71.8 156.9 88.0 85.0 51.8 92.4 61.3 55.1 79.1 71.6 86.0 74.6 72.2 92.0 89.7 68.7 63.8 78.2 9.3 106.1 72.1 46.8 79.2 82.3 19.3 19.8 19.9 26.1 19.4 21.6 22.5 22.6 21.8 19.6 21.9 21.2 17.6 12.8 10.4 2.3 18.7 21.7 21.7 28.2 10.8 9.2 14.8 11.8 11.8 14.3 19.7 14.7 4.2 43.5 28.8 9.5 23.5 46.4 86.3 20.5 14.1 17.3 17.4 18.7 6.6 36.3 46.2 14.3 9.7 21.7 24.7 17.7 17.5 10.2 33.4 11.8 6.6 13.0 20.3 20.1 26.8 76.0 14.9 17.6 23.2 2.8 28.9 15.0 27.8 5.0 5.0 46.3 13.5 10.9 11.2 20.1 16.2 20.8 14.3 10.9 13.1 13.2 19.0 36.6 23.4 13.6 18.6 33.1 31.0 20.2 20.0 18.9 GPR87 GPR95 ENSG00000138271 "G protein-coupled receptor 87" Q9BY21 3 151294086-151316820 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 35.9;skin 1: 32.8;vagina: 23.8" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 139.2;Basal respiratory cells: 150.0;Suprabasal keratinocytes: 68.2;Syncytiotrophoblasts: 205.0;Urothelial cells: 211.4" "Group enriched" "Detected in many" 6 "cervical cancer: 44.1;head and neck cancer: 40.1;lung cancer: 22.0;urothelial cancer: 23.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 110.8;CAPAN-2: 40.8;HaCaT: 90.6;HBEC3-KT: 116.7;hTCEpi: 152.8;hTERT-HME1: 62.2;RT4: 46.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA066313 Approved "Nucleoplasm,Lipid droplets,Mitochondria" No No "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Lipid droplets, Mitochondria" Nucleoplasm "HPA066313: AB_2685656" "unprognostic (5.81e-2)" "unprognostic (2.12e-1)" "unprognostic (4.07e-3)" "unprognostic (8.60e-2)" "unprognostic (1.28e-2)" "unprognostic (4.61e-3)" "unprognostic (3.28e-2)" "unprognostic (1.27e-1)" "prognostic unfavorable (4.62e-6)" "unprognostic (8.64e-2)" "unprognostic (1.50e-3)" "unprognostic (3.66e-4)" "unprognostic (8.73e-2)" "unprognostic (3.80e-2)" "unprognostic (2.17e-1)" 0.0 0.0 0.0 0.0 0.1 0.0 3.3 0.1 0.8 10.0 2.9 0.0 0.0 0.0 3.2 35.9 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 9.6 0.0 4.3 0.0 0.0 13.7 5.5 0.1 32.8 0.0 0.0 0.0 0.0 0.5 0.0 0.1 3.5 0.0 0.0 12.4 13.2 23.8 0.4 110.8 0.0 0.0 0.0 0.0 0.0 24.0 0.0 0.0 0.9 0.2 0.0 40.8 0.0 0.0 0.0 0.6 90.6 0.0 116.7 1.1 0.0 0.1 0.0 1.1 0.0 0.8 0.0 0.0 0.0 152.8 0.1 62.2 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.5 0.1 6.1 0.0 0.0 0.0 3.8 46.7 0.0 0.0 19.0 0.5 0.0 3.1 0.4 0.1 0.0 0.0 10.9 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 1.1 1.0 0.0 59.3 139.2 150.0 46.7 0.0 2.8 1.8 0.1 0.0 49.9 3.7 0.0 59.0 0.4 0.0 0.0 1.2 0.7 3.3 0.0 1.5 0.0 0.0 1.1 0.7 8.7 1.1 0.0 2.4 1.3 0.0 0.0 0.0 4.2 0.0 0.4 0.0 28.5 0.0 3.6 0.1 0.0 0.6 10.6 0.0 0.0 0.0 0.0 1.0 0.0 12.9 0.0 0.0 0.0 60.6 0.0 0.1 19.6 0.0 0.0 0.0 4.1 0.0 0.0 52.7 68.2 205.0 0.9 0.0 0.0 211.4 GPT2 ALT2 ENSG00000166123 "Glutamic--pyruvic transaminase 2" Q8TD30 16 46884362-46931289 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Aminotransferase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 267.4;skeletal muscle: 176.4;tongue: 184.5" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 64.3;Hepatocytes: 123.9;Syncytiotrophoblasts: 83.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.3;naive B-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Hep G2: 159.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051514 Approved Approved Mitochondria No No "Cluster 19: B-cells - Humoral immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA051514: AB_2681516" "unprognostic (1.65e-2)" "unprognostic (3.32e-2)" "unprognostic (2.87e-1)" "unprognostic (3.87e-2)" "unprognostic (3.41e-1)" "unprognostic (1.27e-1)" "unprognostic (1.95e-3)" "unprognostic (3.44e-2)" "unprognostic (6.12e-2)" "prognostic favorable (3.17e-4)" "unprognostic (1.90e-1)" "unprognostic (1.30e-1)" "unprognostic (1.56e-1)" "unprognostic (1.44e-2)" "unprognostic (4.86e-1)" "unprognostic (3.54e-3)" "unprognostic (3.18e-1)" 56.8 10.4 51.6 4.0 49.9 3.8 17.0 49.1 56.9 5.2 38.4 7.7 1.7 3.7 31.4 77.8 7.6 9.8 7.9 51.3 45.7 23.5 103.7 2.1 4.3 69.8 45.9 2.3 267.4 8.3 13.0 3.1 63.9 24.2 4.9 6.9 48.8 10.9 176.4 37.8 3.9 3.1 60.2 2.3 58.6 15.0 54.9 7.7 7.6 184.5 13.4 2.7 7.7 64.5 42.6 19.0 23.8 90.6 32.7 7.0 43.1 28.9 10.9 30.7 19.2 65.3 17.6 29.9 24.7 20.7 15.6 33.6 43.3 42.8 20.4 14.0 21.1 10.5 10.8 159.9 22.4 75.6 9.5 15.2 37.0 30.0 46.3 20.3 15.1 56.1 8.7 23.3 10.3 75.8 15.1 62.9 25.3 52.2 54.2 0.3 26.3 71.1 12.4 21.0 73.7 37.7 14.9 76.4 39.0 9.4 19.6 67.6 11.3 21.1 40.9 14.2 23.4 110.2 36.9 87.1 32.6 48.3 11.7 0.4 0.2 0.0 0.1 0.0 0.0 1.3 0.0 0.1 0.4 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 51.6 49.9 49.1 56.9 51.3 45.7 69.8 45.9 63.9 60.2 54.9 64.5 1.3 6.4 3.4 54.9 4.8 15.9 4.9 6.8 64.3 14.5 6.7 8.4 14.9 8.6 9.1 18.4 22.9 9.2 0.3 10.2 11.7 7.0 9.6 12.2 7.2 2.3 13.1 5.2 16.7 30.2 44.8 7.5 37.2 37.5 3.8 14.9 5.0 123.9 3.8 6.7 18.8 13.4 6.1 3.2 7.3 22.9 4.7 2.3 8.8 1.0 1.1 42.5 1.0 13.6 26.0 25.6 5.2 15.4 7.9 12.4 2.0 38.6 5.4 5.9 0.0 5.2 3.6 2.5 17.3 53.1 16.3 83.3 1.4 2.6 6.3 4.2 GPX4 "MCSP, PHGPx" ENSG00000167468 "Glutathione peroxidase 4" P36969 19 1103926-1106791 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Developmental protein, Oxidoreductase, Peroxidase" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Late spermatids: 18580.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008630, HPA047224, HPA058546" Enhanced Approved Nucleoplasm,Mitochondria "Intracellular and membrane" NA NA 150000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 78: Testis - Spermatogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Mitochondria" "CAB008630: AB_1616685, HPA047224: AB_2679990, HPA058546: AB_2683749" "unprognostic (8.42e-3)" "prognostic favorable (7.18e-4)" "unprognostic (8.14e-3)" "prognostic favorable (1.84e-5)" "unprognostic (1.00e-1)" "unprognostic (8.72e-2)" "unprognostic (2.53e-3)" "unprognostic (8.49e-2)" "unprognostic (2.69e-2)" "unprognostic (1.47e-1)" "prognostic favorable (7.72e-4)" "unprognostic (1.29e-1)" "prognostic favorable (8.61e-4)" "unprognostic (1.61e-2)" "unprognostic (2.20e-1)" "unprognostic (6.67e-3)" "unprognostic (2.96e-2)" 927.8 535.3 415.1 127.4 428.7 178.0 733.3 440.7 519.1 280.8 478.7 249.0 259.0 188.4 318.9 220.4 199.2 196.6 426.0 419.2 450.3 536.5 687.8 307.9 216.4 430.9 448.3 260.3 157.9 285.5 398.4 147.2 454.1 322.1 110.9 167.5 304.9 193.8 672.3 290.4 236.2 87.9 418.2 213.2 219.0 1403.5 444.0 158.7 291.5 399.7 182.5 319.0 245.2 429.1 258.1 286.8 405.8 863.0 1202.1 706.0 449.3 199.3 713.5 371.1 375.9 590.5 339.8 92.8 211.8 405.8 313.5 283.1 239.7 289.3 180.5 522.3 436.5 175.0 246.9 849.2 697.4 207.6 269.4 707.3 432.1 188.3 314.7 665.9 527.1 317.5 249.4 225.7 311.1 660.4 353.8 354.9 386.2 569.7 458.9 482.8 55.3 271.3 408.9 629.9 348.3 220.6 390.5 366.1 422.1 246.7 358.1 498.0 450.9 392.3 257.4 680.6 254.6 786.5 582.0 224.3 369.4 412.2 230.9 578.9 539.6 564.4 219.8 405.4 256.9 352.7 319.7 230.7 404.0 309.9 339.4 245.0 265.1 196.6 462.2 278.8 310.3 841.7 415.1 428.7 440.7 519.1 419.2 450.3 430.9 448.3 454.1 418.2 444.0 429.1 415.9 179.5 189.7 21.2 281.7 510.0 525.8 1188.1 512.2 332.2 845.1 868.2 264.6 316.0 600.6 472.6 98.0 562.5 231.3 479.1 1592.6 515.8 4209.7 546.8 326.3 268.7 397.1 215.0 24.5 368.7 1327.3 536.1 99.9 442.3 346.1 242.6 322.0 826.2 1184.1 208.6 33.1 328.7 671.4 583.1 1304.8 18580.2 384.9 735.2 677.7 21.5 1786.8 502.6 192.6 13.6 35.4 484.0 507.9 312.9 189.2 694.7 1861.9 3024.7 800.9 246.0 243.3 244.6 587.1 1310.8 202.4 357.7 467.0 978.1 281.0 186.7 336.4 662.6 GREB1 KIAA0575 ENSG00000196208 "Growth regulating estrogen receptor binding 1" Q4ZG55 2 11482341-11642788 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "ovary: 278.3" "Cell type enriched" "Detected in many" 9 "Granulosa cells: 545.2" "Cancer enhanced" "Detected in many" "prostate cancer: 17.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 40.3;Hep G2: 39.6;MCF7: 61.8;SH-SY5Y: 40.5;SK-MEL-30: 30.4;T-47d: 138.0" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA024616, HPA027843, HPA028416" Uncertain Approved Mitochondria,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 6: T47d - Mammary gland" "Cluster 40: Granulosa cells - Unknown function" "Mitochondria, Cytosol" "HPA024616: AB_10599728, HPA027843: AB_10601103, HPA028416: AB_10601344" "unprognostic (1.52e-2)" "unprognostic (4.63e-1)" "unprognostic (1.46e-1)" "prognostic favorable (1.05e-4)" "unprognostic (1.23e-2)" "unprognostic (1.32e-1)" "unprognostic (6.29e-2)" "unprognostic (1.24e-1)" "unprognostic (6.19e-2)" "unprognostic (1.38e-1)" "unprognostic (3.68e-1)" "unprognostic (3.63e-2)" "unprognostic (7.51e-4)" "unprognostic (2.42e-2)" "unprognostic (3.34e-1)" "unprognostic (2.46e-3)" "unprognostic (4.80e-2)" 1.8 3.4 8.5 0.7 9.6 0.4 13.7 2.1 9.9 60.2 0.8 1.0 0.7 61.3 7.0 0.6 53.4 2.8 4.6 7.8 20.4 1.8 3.1 1.4 0.6 8.7 8.5 278.3 7.6 0.7 8.9 3.0 4.4 63.4 0.2 1.5 1.1 3.8 4.0 2.7 0.9 12.8 3.2 0.2 3.0 14.9 10.7 0.3 0.6 4.8 0.3 1.7 21.5 6.5 0.1 1.0 40.3 0.5 0.2 0.2 1.8 0.0 0.1 0.1 0.3 0.3 0.2 2.5 0.3 0.0 6.9 0.2 3.1 0.2 0.1 5.1 3.6 0.4 0.3 39.6 0.5 0.3 2.1 0.5 2.2 0.6 0.4 0.4 0.0 3.9 0.5 1.0 0.3 61.8 1.2 2.0 13.0 0.1 0.1 29.1 0.0 1.9 0.1 0.0 11.8 40.5 0.9 1.1 30.4 5.2 138.0 0.7 0.0 4.1 2.0 0.4 0.1 6.0 4.4 24.7 6.8 11.9 1.2 0.6 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.4 0.1 0.1 0.1 0.1 0.0 8.5 9.6 2.1 9.9 7.8 20.4 8.7 8.5 4.4 3.2 10.7 6.5 0.4 0.0 0.5 20.2 0.7 0.8 1.9 0.0 0.6 4.8 24.7 13.7 8.3 5.7 0.6 0.0 2.1 0.2 0.1 0.1 0.0 0.3 0.8 35.7 36.0 1.3 0.0 0.0 15.0 0.2 3.6 16.9 0.0 23.4 3.8 545.2 0.7 8.9 3.2 3.3 46.9 0.0 0.0 0.0 1.2 2.5 20.2 1.4 5.4 1.0 0.0 0.2 0.0 11.6 20.9 0.4 0.0 55.3 5.0 14.3 0.0 2.5 2.9 0.5 0.0 7.2 14.8 1.1 2.9 0.3 0.3 0.3 1.1 33.1 0.0 2.5 GREB1L "C18orf6, FLJ13687, KIAA1772" ENSG00000141449 "GREB1 like retinoic acid receptor coactivator" Q9C091 18 21242242-21525417 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 9.2" "Cell type enhanced" "Detected in many" "Granulosa cells: 95.2;Inhibitory neurons: 39.2;Leydig cells: 46.0;Oligodendrocytes: 252.5" "Cancer enhanced" "Detected in some" "breast cancer: 1.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 50.7;BEWO: 100.9;CACO-2: 45.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA041647, HPA044218" Uncertain Approved Mitochondria NA NA "Cluster 38: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "HPA041647: AB_2677597, HPA044218: AB_2678859" "unprognostic (1.88e-3)" "unprognostic (9.01e-4)" "unprognostic (2.92e-1)" "unprognostic (2.45e-1)" "unprognostic (5.03e-2)" "unprognostic (3.67e-3)" "unprognostic (3.65e-1)" "unprognostic (1.11e-2)" "unprognostic (1.07e-1)" "unprognostic (1.97e-1)" "unprognostic (4.32e-3)" "unprognostic (2.87e-2)" "unprognostic (3.30e-8)" "unprognostic (4.72e-3)" "unprognostic (1.89e-1)" "unprognostic (8.80e-2)" "unprognostic (1.35e-1)" 2.6 1.4 5.5 0.1 4.3 0.2 3.3 3.5 3.6 1.2 0.0 0.6 0.1 2.6 2.8 0.2 4.4 0.1 5.3 2.6 8.1 0.4 1.8 0.2 0.1 4.0 4.7 3.7 0.1 0.3 1.2 2.1 4.1 1.6 0.1 3.1 0.5 2.9 9.2 1.3 0.5 0.8 1.7 0.0 0.6 6.2 6.4 0.0 3.8 6.8 0.0 0.1 0.7 4.4 0.0 0.9 50.7 0.0 11.4 0.0 100.9 2.4 2.4 4.3 3.8 45.7 3.7 0.1 5.1 7.6 0.1 9.7 19.4 2.4 7.5 0.7 9.3 0.0 13.4 0.4 0.3 0.0 0.0 0.0 0.7 0.1 9.3 0.5 0.0 1.4 0.0 0.3 10.5 3.5 0.2 0.2 4.9 0.4 6.0 0.2 0.0 2.0 4.8 8.7 3.2 0.0 0.1 1.6 0.2 13.2 2.7 0.2 20.9 0.5 2.9 4.9 0.0 0.1 0.7 0.0 2.2 0.0 0.4 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.5 4.3 3.5 3.6 2.6 8.1 4.0 4.7 4.1 1.7 6.4 4.4 0.4 0.0 0.5 0.7 0.4 0.1 0.1 1.0 0.0 32.3 3.1 1.1 13.4 0.0 1.1 3.7 2.1 3.2 1.8 0.1 0.0 0.2 8.3 2.2 3.4 0.5 0.0 0.0 23.1 0.4 13.2 6.2 0.0 7.0 0.0 95.2 0.0 3.1 0.5 0.0 39.2 0.2 0.0 0.0 1.1 17.9 46.0 0.3 1.8 2.8 0.1 0.8 2.1 8.0 252.5 2.8 0.0 35.7 0.0 0.6 0.3 0.0 2.3 1.6 6.6 2.8 2.3 4.3 5.6 0.0 0.9 1.5 0.3 10.5 1.5 0.2 GRK6 GPRK6 ENSG00000198055 "G protein-coupled receptor kinase 6" P43250 5 177403204-177442901 "Enzymes, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 134.1" "Cell type enhanced" "Detected in many" "Late spermatids: 90.6;NK-cells: 123.6;Plasma cells: 112.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015327, HPA018903" Approved Approved Mitochondria NA NA 170000 "Cluster 52: Eosinophils - Transcription" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Mitochondria "HPA015327: AB_1850334, HPA018903: AB_1850335" "unprognostic (1.06e-1)" "unprognostic (3.39e-2)" "unprognostic (4.46e-2)" "unprognostic (3.87e-2)" "unprognostic (2.35e-3)" "unprognostic (1.53e-1)" "prognostic unfavorable (5.66e-6)" "unprognostic (2.63e-1)" "unprognostic (6.45e-2)" "unprognostic (8.96e-2)" "prognostic favorable (1.22e-4)" "unprognostic (1.74e-2)" "unprognostic (1.99e-2)" "unprognostic (1.83e-3)" "unprognostic (1.15e-1)" "unprognostic (4.00e-2)" "unprognostic (3.47e-1)" 14.0 10.8 12.6 36.7 12.3 134.1 12.7 8.1 16.0 11.3 9.2 19.7 18.5 14.8 2.4 21.5 13.3 12.4 13.3 12.7 9.6 11.0 13.6 21.8 61.6 13.3 10.5 11.1 13.3 5.5 10.5 6.8 11.1 15.8 8.8 2.2 17.9 7.4 15.7 15.5 29.1 9.2 8.9 63.3 15.9 22.3 10.7 35.9 10.2 6.2 30.2 16.6 13.2 13.9 41.1 44.2 15.7 67.8 4.6 7.4 66.4 29.4 15.1 36.2 35.5 103.0 34.1 48.7 44.0 15.6 53.5 29.1 24.3 67.0 14.3 133.9 77.3 43.5 36.2 36.0 24.1 58.6 52.8 11.7 16.1 36.2 21.4 8.8 20.5 87.8 45.6 170.9 11.2 117.4 61.3 61.4 26.7 20.4 48.1 57.1 25.5 71.2 10.7 32.9 36.0 48.6 24.3 42.5 56.8 7.1 32.6 63.4 26.3 29.6 43.8 31.2 75.1 48.8 64.2 40.7 20.0 95.0 29.2 12.7 20.9 74.5 23.6 36.5 17.0 19.3 19.6 21.9 11.9 19.5 20.3 18.0 50.6 40.3 51.9 12.5 26.4 22.6 12.6 12.3 8.1 16.0 12.7 9.6 13.3 10.5 11.1 8.9 10.7 13.9 9.2 0.0 2.2 2.6 71.7 23.7 60.3 4.9 5.7 10.5 14.7 17.3 3.0 10.0 4.6 3.7 6.2 13.9 70.8 18.2 15.6 6.0 37.2 7.4 8.2 6.6 11.4 41.7 3.7 8.3 12.6 9.7 16.8 6.4 14.7 13.9 10.0 6.5 20.4 16.8 3.5 14.3 4.1 29.8 18.8 90.6 6.2 41.2 14.2 2.8 26.4 9.0 123.6 2.0 3.3 10.3 14.0 5.3 112.2 61.1 11.8 8.5 2.0 8.6 13.1 8.4 10.7 3.9 4.2 11.9 20.3 12.7 66.5 12.1 17.1 56.6 GRK7 GPRK7 ENSG00000114124 "G protein-coupled receptor kinase 7" Q8WTQ7 3 141778148-141818490 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Sensory transduction, Vision" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 19 "retina: 11.3" "Cell type enriched" "Detected in some" 73 "Cone photoreceptor cells: 329.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA075093, HPA078232" Enhanced Approved Mitochondria NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 79: Retina - Phototransduction" "Cluster 9: Photoreceptor cells - Phototransduction" Mitochondria "HPA075093: , HPA078232: " "unprognostic (1.11e-1)" "unprognostic (1.70e-2)" "unprognostic (3.35e-3)" "unprognostic (1.22e-2)" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (1.39e-2)" "unprognostic (5.08e-2)" "unprognostic (1.21e-1)" "unprognostic (1.31e-2)" "unprognostic (3.46e-2)" "unprognostic (1.20e-1)" "unprognostic (2.53e-8)" "unprognostic (3.08e-1)" "unprognostic (1.99e-1)" "unprognostic (3.11e-1)" "unprognostic (2.91e-1)" 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.5 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 11.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.1 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.0 3.9 0.1 0.4 0.2 0.0 0.6 1.0 0.1 0.1 0.2 0.0 0.0 0.0 329.4 0.0 0.2 0.0 0.0 0.0 1.0 0.1 0.1 0.1 0.0 0.0 2.5 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.0 2.1 0.0 0.0 0.0 0.4 2.4 0.0 0.1 0.0 1.9 0.1 1.1 0.0 4.5 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.5 0.1 0.1 0.0 0.2 0.3 0.0 0.1 0.3 0.1 0.0 GSDMC MLZE ENSG00000147697 "Gasdermin C" Q9BYG8 8 129748196-129786624 "Predicted intracellular proteins, Transporters" Necrosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 33.1;lymphoid tissue: 12.8;skin 1: 25.5;vagina: 11.4" "Group enriched" "Detected in some" 4 "Basal keratinocytes: 46.5;Basal squamous epithelial cells: 37.5;Squamous epithelial cells: 29.5;Suprabasal keratinocytes: 53.1" "Cancer enhanced" "Detected in many" "cervical cancer: 11.8;head and neck cancer: 19.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 5.2;HaCaT: 3.7;hTCEpi: 1.8;HUVEC TERT2: 2.0;TIME: 5.8" "Low region specificity" "Detected in many" "HPA023670, HPA024767, HPA026317" Supported Approved Mitochondria NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Mitochondria "HPA023670: AB_1854006, HPA024767: AB_1854007, HPA026317: AB_1854008" "unprognostic (6.33e-3)" "unprognostic (1.49e-1)" "unprognostic (2.61e-3)" "unprognostic (4.23e-2)" "unprognostic (2.11e-2)" "unprognostic (4.22e-3)" "unprognostic (1.43e-2)" "unprognostic (1.15e-1)" "unprognostic (8.28e-2)" "unprognostic (7.51e-2)" "unprognostic (4.92e-3)" "unprognostic (5.71e-2)" "unprognostic (2.93e-3)" "unprognostic (1.87e-2)" "unprognostic (1.88e-1)" "unprognostic (8.66e-2)" "unprognostic (1.90e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 4.4 0.0 0.0 0.0 0.0 0.1 33.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 5.4 0.0 0.0 25.5 0.0 0.0 0.0 12.8 0.0 0.0 0.0 0.0 0.0 0.0 4.0 2.4 11.4 0.1 5.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.7 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 2.0 1.0 0.0 46.5 0.9 7.4 37.5 0.0 1.5 0.9 3.6 0.0 9.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.2 0.2 0.0 0.9 0.0 0.0 0.1 0.2 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 6.1 0.0 3.9 0.0 0.0 0.2 7.2 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.0 0.4 0.0 0.0 1.3 0.0 0.0 0.1 0.5 0.0 0.1 29.5 53.1 0.0 0.1 0.0 0.0 2.8 GSE1 KIAA0182 ENSG00000131149 "Gse1 coiled-coil protein" Q14687 16 85169525-85676204 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 146.0;Syncytiotrophoblasts: 182.2" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 24.4" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BEWO: 174.6;K-562: 205.4;T-47d: 200.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036365, HPA042090" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 52: Non-specific - Transcription" Mitochondria Nucleoplasm "HPA036365: AB_10601762, HPA042090: " "unprognostic (1.12e-2)" "unprognostic (6.29e-2)" "unprognostic (1.12e-1)" "unprognostic (4.57e-2)" "unprognostic (5.31e-2)" "unprognostic (1.63e-1)" "unprognostic (1.76e-1)" "unprognostic (1.77e-1)" "unprognostic (2.60e-1)" "unprognostic (6.41e-2)" "prognostic favorable (5.20e-4)" "unprognostic (2.29e-3)" "unprognostic (1.32e-3)" "unprognostic (8.41e-2)" "unprognostic (8.46e-2)" "unprognostic (3.81e-1)" "unprognostic (1.88e-1)" 27.2 15.2 1.4 14.2 0.7 31.9 22.0 24.4 7.9 16.9 0.0 17.9 15.9 15.1 5.0 12.7 15.9 10.6 23.2 3.9 3.0 12.3 14.2 17.7 11.3 4.5 5.8 23.7 23.4 38.6 28.0 31.7 2.1 12.7 11.5 14.4 30.3 13.6 37.9 18.8 14.8 14.2 0.0 18.4 20.8 14.7 2.0 40.7 19.3 9.3 8.7 13.0 14.1 0.7 19.3 33.6 22.0 55.5 13.9 12.7 174.6 25.3 17.4 13.9 5.2 29.0 25.6 11.2 29.9 28.9 12.5 17.9 35.1 9.7 7.0 21.2 29.7 82.4 33.6 36.5 17.9 38.5 44.8 23.7 22.7 14.9 7.1 14.5 3.7 65.7 205.4 2.0 4.6 129.9 138.1 33.9 38.4 20.7 9.9 89.7 7.4 29.1 12.6 7.2 142.7 99.3 49.8 91.8 4.7 19.9 200.7 94.6 6.4 28.3 35.5 7.9 6.9 30.0 19.5 65.3 16.2 23.8 25.4 2.8 0.7 2.2 1.4 1.3 1.4 1.6 0.5 0.9 1.2 1.5 0.2 1.0 0.6 0.9 3.3 0.0 0.0 0.6 1.4 0.7 24.4 7.9 3.9 3.0 4.5 5.8 2.1 0.0 2.0 0.7 52.9 67.3 68.1 30.3 16.6 14.0 7.3 11.6 21.1 65.0 39.6 16.8 37.0 25.8 24.1 38.6 146.0 52.9 25.5 33.6 1.9 14.9 4.3 48.8 34.7 27.0 59.7 65.6 53.2 12.4 75.9 21.7 39.3 61.6 43.6 80.9 17.2 34.7 12.3 35.3 45.4 67.5 20.3 15.1 24.0 5.5 47.2 17.5 10.6 19.7 12.2 7.1 35.0 14.1 13.7 17.9 20.9 61.3 18.6 14.3 12.6 6.2 30.5 62.3 6.6 15.5 10.1 2.3 18.3 33.5 30.0 182.2 21.5 55.8 25.7 12.3 GTPBP6 "FLJ20977, PGPL" ENSG00000178605 "GTP binding protein 6 (putative)" O43824 X 304529-318819 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA013336, CAB034924, HPA035467, HPA055418" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoplasm "CAB034924: AB_2115410, HPA013336: , HPA035467: AB_10671104, HPA055418: " "unprognostic (5.00e-2)" "unprognostic (5.10e-2)" "unprognostic (1.60e-1)" "unprognostic (1.10e-2)" "unprognostic (4.90e-2)" "unprognostic (2.30e-3)" "prognostic unfavorable (8.87e-4)" "unprognostic (1.17e-1)" "unprognostic (2.95e-1)" "unprognostic (6.10e-2)" "prognostic favorable (1.71e-4)" "unprognostic (3.38e-2)" "unprognostic (4.45e-2)" "unprognostic (4.99e-3)" "unprognostic (2.23e-1)" "unprognostic (2.35e-1)" "unprognostic (5.05e-2)" 31.4 24.2 22.5 17.2 24.3 26.2 29.9 22.2 33.2 25.8 17.3 29.6 19.7 28.1 3.2 26.7 29.6 9.9 46.5 20.9 19.7 33.1 38.7 25.9 19.3 26.9 23.4 30.5 42.6 12.0 17.0 9.6 23.7 26.1 5.8 4.1 30.1 12.3 69.4 30.8 26.3 6.8 21.3 26.8 35.8 13.4 22.2 13.2 27.5 27.1 6.9 29.6 22.6 30.7 40.4 65.4 14.2 29.9 16.1 17.5 52.6 24.5 18.0 30.4 27.7 100.8 32.9 50.1 34.0 13.8 41.3 24.6 15.0 23.9 4.9 42.1 44.1 41.5 32.2 70.0 43.2 28.2 38.9 21.7 31.0 20.3 14.8 11.2 24.7 32.8 31.1 23.0 12.7 79.5 50.4 37.1 34.8 8.1 46.0 22.3 25.0 80.7 17.9 46.3 39.8 33.9 26.8 30.0 46.2 7.6 26.9 24.3 33.0 44.2 30.4 66.0 38.3 30.9 30.1 78.0 23.0 36.8 20.9 5.3 4.1 4.8 4.8 4.3 4.8 4.9 4.2 5.5 4.0 3.4 5.1 4.6 0.5 3.7 4.0 7.3 6.3 2.6 22.5 24.3 22.2 33.2 20.9 19.7 26.9 23.4 23.7 21.3 22.2 30.7 35.3 19.2 19.2 17.0 33.8 28.2 48.2 7.9 34.7 28.1 38.1 34.0 20.3 32.9 9.2 27.6 27.1 22.0 45.1 32.1 52.8 13.1 1.4 20.1 27.3 26.2 17.9 16.6 10.9 15.0 46.0 32.9 37.8 23.6 11.4 44.9 21.0 38.1 29.3 13.5 9.6 24.7 16.2 25.7 28.0 1.6 19.6 32.6 26.6 6.5 16.7 22.0 33.0 12.1 18.7 10.4 17.4 18.8 32.5 98.1 23.2 89.5 6.7 27.2 6.6 33.2 31.2 4.5 13.5 36.9 26.6 29.4 38.9 54.3 38.1 51.2 GUF1 FLJ13220 ENSG00000151806 "GUF1 homolog, GTPase" Q8N442 4 44678420-44700928 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein biosynthesis" Hydrolase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003934, HPA024222" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Mitochondria" "HPA003934: AB_1079034, HPA024222: AB_2671488" "unprognostic (1.32e-2)" "unprognostic (1.55e-1)" "unprognostic (1.66e-2)" "unprognostic (3.65e-3)" "unprognostic (7.56e-2)" "unprognostic (1.37e-1)" "unprognostic (5.59e-2)" "unprognostic (2.60e-1)" "unprognostic (1.37e-2)" "unprognostic (3.03e-2)" "unprognostic (1.56e-3)" "unprognostic (7.38e-3)" "prognostic favorable (2.66e-6)" "unprognostic (4.98e-3)" "unprognostic (1.74e-1)" "prognostic unfavorable (1.65e-5)" "unprognostic (5.40e-2)" 5.2 4.1 2.5 3.9 3.2 6.3 5.2 4.3 3.6 3.5 0.6 5.7 4.6 4.8 3.8 5.2 4.1 2.7 6.1 3.3 2.5 6.9 7.1 3.1 4.7 1.6 1.9 4.9 3.7 4.3 2.4 3.7 1.9 4.9 5.9 6.7 4.0 3.5 15.8 5.0 6.3 3.5 2.4 4.8 7.9 5.9 2.2 4.4 5.3 17.0 4.6 3.9 3.8 4.4 11.9 6.0 10.9 13.9 4.4 9.0 24.0 16.1 8.2 16.2 12.4 10.5 8.3 25.8 12.3 7.7 14.9 9.2 18.7 18.2 18.2 8.7 12.2 30.7 5.3 7.2 14.3 33.4 12.7 9.2 8.1 12.1 10.5 7.6 11.8 15.0 31.7 4.9 13.2 5.9 19.1 7.0 7.0 8.5 13.8 13.5 22.5 11.0 4.8 4.6 14.8 11.1 10.1 4.2 11.2 8.4 6.8 9.6 11.7 11.0 12.7 14.8 19.1 17.9 17.4 18.3 11.9 19.7 9.6 0.5 2.2 2.3 2.0 2.9 2.6 2.1 2.1 1.8 2.1 1.7 1.9 2.0 0.0 2.3 1.9 2.3 3.6 1.9 2.5 3.2 4.3 3.6 3.3 2.5 1.6 1.9 1.9 2.4 2.2 4.4 7.2 6.4 9.5 9.8 11.6 4.0 9.6 6.0 5.2 10.5 9.8 7.5 22.8 7.2 9.1 7.3 2.1 13.1 10.1 11.5 13.7 10.3 2.0 12.0 14.3 8.1 11.4 14.9 20.3 10.2 17.6 9.7 18.3 8.8 1.3 16.6 7.9 13.9 12.1 11.8 19.5 12.4 4.1 11.7 5.4 2.9 5.6 9.0 7.2 9.4 9.2 9.2 14.4 18.6 19.0 16.4 6.6 7.2 13.9 9.8 11.3 12.2 16.7 10.3 0.0 6.8 10.0 12.3 14.6 14.9 7.1 13.4 9.5 18.9 13.3 10.6 HDGFL2 "Hdgfrp2, HRP2" ENSG00000167674 "HDGF like 2" Q7Z4V5 19 4472297-4502208 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 37.0;Endometrial stromal cells: 31.0;Extravillous trophoblasts: 30.1;Granulosa cells: 44.7;Theca cells: 42.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 5.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042559, HPA044208" Enhanced Supported Nucleoplasm,Mitochondria No No "Cluster 24: B-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Mitochondria "HPA042559: AB_2678049, HPA044208: AB_2678858" "unprognostic (1.33e-1)" "unprognostic (2.38e-2)" "unprognostic (5.47e-3)" "unprognostic (6.57e-3)" "unprognostic (6.80e-2)" "unprognostic (1.96e-2)" "unprognostic (1.52e-2)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" "unprognostic (1.97e-1)" "prognostic favorable (6.57e-4)" "unprognostic (2.12e-2)" "unprognostic (1.36e-1)" "unprognostic (9.73e-3)" "unprognostic (4.75e-1)" "unprognostic (1.58e-1)" "unprognostic (2.05e-1)" 27.2 29.0 24.8 16.5 25.5 14.4 28.1 24.2 32.3 42.9 17.8 40.4 15.7 39.3 9.6 29.4 35.6 10.0 32.0 27.4 20.5 31.2 31.3 25.4 17.7 22.9 22.2 49.5 26.9 12.5 38.3 15.0 22.0 36.4 7.6 10.8 26.0 18.6 67.8 29.3 27.0 12.6 19.7 33.4 28.1 74.6 22.2 18.6 29.3 19.1 11.8 34.2 34.8 24.6 71.6 41.2 70.1 65.5 29.9 30.3 49.0 56.2 30.1 60.4 53.3 47.5 30.4 62.6 32.1 41.6 31.8 40.2 46.9 51.1 35.2 70.4 74.7 38.6 32.4 63.5 38.5 38.3 52.8 43.5 27.4 41.6 20.2 42.8 55.9 57.8 45.1 76.3 29.6 50.6 86.9 76.4 80.2 28.5 73.3 85.4 57.6 40.6 38.0 35.8 77.0 76.1 54.7 31.0 47.2 38.1 30.6 60.2 74.8 38.0 51.7 72.3 54.1 94.1 52.9 43.6 53.2 60.8 41.1 0.0 0.9 1.7 0.6 0.6 0.1 0.5 0.7 0.5 0.7 5.6 1.1 0.4 0.2 1.3 0.3 1.0 1.0 0.5 24.8 25.5 24.2 32.3 27.4 20.5 22.9 22.2 22.0 19.7 22.2 24.6 25.5 6.4 5.4 0.0 2.3 0.0 0.0 0.0 0.0 0.0 13.3 15.2 0.0 0.0 5.0 12.9 0.0 37.0 14.3 0.0 19.6 26.4 0.0 26.9 31.0 9.8 0.0 0.0 0.0 19.8 30.1 13.9 0.0 19.8 1.3 44.7 0.0 0.0 25.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 0.0 0.0 15.0 0.0 0.0 0.0 0.0 22.5 0.0 0.0 2.3 0.0 0.0 23.6 9.5 0.0 0.0 0.0 17.8 0.0 0.0 0.0 0.0 15.2 7.1 42.7 0.0 0.0 HDHD5 CECR5 ENSG00000069998 "Haloacid dehalogenase like hydrolase domain containing 5" Q9BXW7 22 17137511-17165287 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 43.0;Ductal cells: 35.2;Extravillous trophoblasts: 42.2;Granulosa cells: 37.0;Hofbauer cells: 42.3;Proximal tubular cells: 41.1;Theca cells: 55.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005548 Approved Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA005548: AB_1078497" "unprognostic (4.04e-2)" "unprognostic (5.04e-2)" "unprognostic (4.54e-3)" "unprognostic (6.61e-2)" "unprognostic (1.20e-1)" "unprognostic (5.71e-2)" "unprognostic (1.04e-3)" "unprognostic (7.35e-2)" "unprognostic (1.70e-1)" "unprognostic (4.98e-2)" "unprognostic (5.76e-2)" "unprognostic (2.35e-1)" "unprognostic (1.10e-1)" "unprognostic (7.07e-3)" "unprognostic (1.71e-1)" "unprognostic (1.20e-2)" "unprognostic (7.21e-3)" 17.4 29.7 15.0 13.2 15.3 16.5 17.3 15.4 15.7 12.9 16.7 21.5 26.5 14.6 6.8 21.7 13.6 9.8 45.0 15.4 14.8 19.8 40.5 12.6 14.5 15.4 14.9 12.2 20.9 17.5 11.6 8.1 14.6 15.5 14.1 5.7 18.6 10.0 46.9 23.0 17.2 11.4 14.8 19.3 19.9 15.9 15.9 13.6 10.1 55.7 12.0 16.5 14.1 15.0 64.0 41.5 30.5 41.5 17.7 10.8 38.8 17.9 19.6 47.1 50.2 61.1 23.3 103.9 29.3 21.6 23.0 44.0 38.7 42.0 21.8 31.6 56.7 0.0 30.7 0.0 29.4 47.6 23.5 26.1 51.1 21.0 23.1 26.4 33.3 67.4 31.0 26.2 24.9 62.1 84.2 97.2 46.6 97.9 36.7 47.4 45.8 26.3 32.2 34.7 61.4 46.5 34.9 49.9 54.3 23.9 50.1 58.5 29.1 39.7 29.4 28.2 31.3 41.3 48.5 77.8 32.0 0.1 34.2 12.3 86.2 4.7 28.4 56.7 35.6 24.6 26.4 25.8 74.5 23.6 34.3 29.3 4.5 30.7 31.4 30.9 29.7 48.0 15.0 15.3 15.4 15.7 15.4 14.8 15.4 14.9 14.6 14.8 15.9 15.0 21.5 6.4 2.8 0.0 3.6 0.0 0.0 0.0 0.0 0.0 23.9 22.4 0.0 0.0 5.0 5.5 0.0 26.5 9.3 0.0 43.0 35.2 0.0 8.4 14.9 9.2 0.0 0.0 0.0 28.2 42.2 7.7 0.0 11.5 5.1 37.0 0.0 0.0 42.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 5.2 0.0 0.0 0.0 0.0 22.9 0.0 0.0 0.5 0.0 0.0 41.1 1.5 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 15.7 3.4 55.8 0.0 0.0 HEATR6 "ABC1, FLJ22087" ENSG00000068097 "HEAT repeat containing 6" Q6AI08 17 60041008-60078922 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 64.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030789, HPA062157" Uncertain Approved Mitochondria NA NA "Cluster 37: B-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA030789: AB_10601660, HPA062157: AB_2684700" "unprognostic (1.98e-1)" "unprognostic (7.95e-2)" "unprognostic (4.32e-1)" "prognostic unfavorable (2.03e-4)" "unprognostic (4.22e-1)" "unprognostic (1.00e-1)" "prognostic unfavorable (5.02e-6)" "unprognostic (2.24e-1)" "unprognostic (2.86e-1)" "unprognostic (1.97e-1)" "unprognostic (6.81e-3)" "unprognostic (9.84e-2)" "prognostic unfavorable (6.73e-4)" "unprognostic (5.01e-2)" "unprognostic (1.81e-1)" "unprognostic (5.50e-2)" "unprognostic (2.11e-1)" 4.5 7.2 5.3 2.1 6.0 3.1 4.3 6.8 5.9 6.7 4.4 7.4 1.8 7.1 3.2 4.6 6.6 1.9 5.1 5.1 5.3 4.1 3.6 5.0 3.0 6.2 5.4 7.7 5.1 3.4 7.3 2.7 6.2 5.7 2.3 5.2 5.2 3.5 6.0 5.5 6.1 2.7 5.4 7.2 4.9 4.9 5.8 3.0 4.6 2.4 2.2 6.5 5.2 7.8 4.8 13.0 9.5 7.5 5.1 9.1 6.9 4.5 8.9 8.8 9.7 5.2 3.6 1.8 7.8 8.0 7.1 4.9 5.6 6.0 11.9 4.1 7.2 9.3 8.8 9.7 5.6 7.0 10.1 7.1 8.8 6.4 7.6 9.5 4.7 6.0 5.9 5.1 6.6 64.6 8.9 3.6 5.9 3.9 8.7 3.2 16.9 5.8 5.7 7.1 5.4 13.7 4.6 1.6 6.6 8.2 7.9 5.6 4.5 8.9 15.0 8.2 8.4 6.5 7.1 0.1 7.6 5.1 6.9 2.4 3.4 3.4 3.4 5.4 3.2 8.2 2.5 2.5 6.0 4.3 3.3 2.6 0.5 3.0 5.6 2.9 2.9 2.7 5.3 6.0 6.8 5.9 5.1 5.3 6.2 5.4 6.2 5.4 5.8 7.8 4.6 12.8 6.3 9.4 8.0 0.9 2.8 6.2 6.2 11.1 3.1 5.0 9.2 2.8 8.1 7.3 10.4 5.7 5.0 1.1 3.9 4.8 1.0 4.8 9.1 5.1 6.7 3.0 13.1 3.3 3.4 7.4 6.6 4.3 11.4 8.8 4.2 2.8 4.6 6.7 13.7 1.5 4.1 5.6 2.6 0.7 3.4 8.5 1.8 15.9 15.3 8.8 7.2 16.6 25.3 2.9 1.0 11.3 3.3 1.7 1.5 3.3 10.5 6.6 6.6 6.5 15.4 5.1 7.7 3.6 2.3 2.1 7.6 10.1 3.1 1.2 HEXD "FLJ23825, HEXDC" ENSG00000169660 "Hexosaminidase D" Q8WVB3 17 82418318-82442645 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 7.8;Cardiomyocytes: 6.1;Cytotrophoblasts: 5.9;dendritic cells: 10.1;Extravillous trophoblasts: 6.4;Hofbauer cells: 16.2;Plasma cells: 4.1;Syncytiotrophoblasts: 4.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 62.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022834, HPA023379, HPA027844" Uncertain Approved "Nucleoli fibrillar center,Mitochondria" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 50: Non-specific - Ribosome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 24: Non-specific - Transcription regulation" "Nucleoli fibrillar center, Mitochondria" "HPA022834: AB_1850641, HPA023379: AB_1850643, HPA027844: AB_10600711" "unprognostic (8.69e-3)" "prognostic favorable (7.70e-4)" "unprognostic (7.92e-2)" "unprognostic (1.53e-1)" "unprognostic (3.51e-2)" "prognostic favorable (2.71e-4)" "unprognostic (1.31e-1)" "unprognostic (2.11e-2)" "unprognostic (2.71e-1)" "unprognostic (1.14e-2)" "prognostic favorable (5.57e-4)" "unprognostic (9.04e-3)" "unprognostic (1.83e-1)" "unprognostic (3.81e-2)" "unprognostic (2.92e-1)" "unprognostic (1.24e-1)" "prognostic favorable (2.52e-5)" 31.5 20.5 6.9 4.4 7.4 9.0 21.0 10.1 7.8 32.5 9.3 17.0 4.1 22.4 3.9 15.4 25.3 3.1 15.0 6.6 6.3 27.0 29.8 14.8 7.0 7.6 7.0 29.9 55.2 4.1 31.9 1.8 8.0 34.6 2.1 3.6 19.8 4.2 28.4 14.4 24.2 2.1 6.2 36.1 21.3 12.5 7.8 5.0 25.4 7.6 3.4 17.6 21.1 9.6 3.4 8.0 3.5 5.9 11.3 9.9 10.7 4.5 5.4 4.4 4.7 3.1 11.1 9.5 4.8 1.7 3.0 4.9 2.0 2.5 1.7 6.4 15.5 4.1 8.4 3.9 9.9 2.9 10.2 7.3 1.9 1.3 4.6 4.7 5.7 5.9 5.5 3.2 1.3 7.5 10.0 8.6 3.7 6.5 5.1 11.5 3.2 17.9 3.5 4.5 4.9 11.1 9.4 5.5 9.1 1.3 8.4 10.7 5.2 2.8 5.3 2.2 3.1 14.6 2.1 7.0 2.3 6.9 3.2 9.5 3.0 5.6 18.4 24.3 12.4 8.3 3.9 6.5 3.8 11.0 5.8 9.3 5.5 25.4 10.8 62.3 3.2 11.2 6.9 7.4 10.1 7.8 6.6 6.3 7.6 7.0 8.0 6.2 7.8 9.6 7.8 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 5.9 10.1 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 6.4 3.4 0.0 0.0 0.0 0.0 0.0 0.0 16.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 4.0 1.4 0.0 0.0 0.0 HEYL "bHLHb33, HESR3, HEY3" ENSG00000163909 "Hes related family bHLH transcription factor with YRPW motif like" Q9NQ87 1 39623435-39639643 "Predicted intracellular proteins, Transcription factors" "Notch signaling pathway, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 69.5" "Cell type enhanced" "Detected in many" "Late spermatids: 17.5;Leydig cells: 26.1;Peritubular cells: 56.8;Sertoli cells: 52.6;Skeletal myocytes: 33.4;Smooth muscle cells: 29.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "JURKAT: 8.0;LHCN-M2: 20.8;RH-30: 26.5;THP-1: 6.2;U-266/84: 7.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001438, HPA076960" Approved Approved Mitochondria,Cytosol NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria Cytosol "HPA001438: AB_1079052, HPA076960: AB_2732326" "unprognostic (1.98e-2)" "unprognostic (7.92e-2)" "unprognostic (4.19e-3)" "unprognostic (3.49e-1)" "unprognostic (2.08e-1)" "unprognostic (1.41e-1)" "unprognostic (1.35e-1)" "unprognostic (7.20e-2)" "unprognostic (5.92e-2)" "unprognostic (1.19e-2)" "unprognostic (2.35e-1)" "unprognostic (8.50e-2)" "prognostic unfavorable (2.26e-6)" "prognostic unfavorable (3.57e-4)" "unprognostic (2.67e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (2.63e-5)" 17.9 12.4 9.5 5.6 12.0 0.1 9.3 10.5 6.9 18.5 4.1 7.2 1.9 27.9 5.7 4.8 17.4 8.0 57.0 5.4 15.0 9.5 4.2 23.5 1.7 11.3 15.6 13.4 69.5 2.4 15.3 29.5 12.9 17.0 3.4 6.7 2.7 14.4 6.0 2.9 4.9 25.0 7.3 6.3 6.0 16.0 17.1 1.3 20.4 5.4 2.0 8.7 11.3 8.3 0.0 2.8 4.8 0.0 0.0 0.5 0.3 0.0 0.1 0.0 0.1 2.0 0.3 0.0 1.6 0.5 0.0 0.0 2.8 0.0 0.3 0.0 3.2 5.2 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 8.0 0.5 0.7 20.8 1.9 0.0 0.1 0.0 0.2 0.1 1.4 26.5 0.2 0.0 0.5 0.6 0.0 0.0 0.1 0.0 1.1 0.0 6.2 0.0 0.0 0.2 0.0 0.0 0.7 7.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 12.0 10.5 6.9 5.4 15.0 11.3 15.6 12.9 7.3 17.1 8.3 1.3 0.0 0.0 0.7 0.0 0.9 0.1 0.0 0.0 0.9 0.1 0.0 3.6 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 1.0 5.4 1.3 4.0 1.9 0.0 0.0 0.1 3.5 0.3 13.3 2.0 2.4 0.0 0.7 1.4 0.0 0.3 1.7 0.2 0.2 0.0 0.0 2.3 17.5 26.1 0.4 5.4 4.7 0.1 0.4 0.0 0.0 2.4 2.8 0.3 56.8 0.0 0.2 0.0 0.1 0.0 3.9 52.6 33.4 29.5 0.4 2.0 0.1 0.1 0.3 0.3 1.9 0.4 0.2 HINT3 "FLJ33126, HINT4" ENSG00000111911 "Histidine triad nucleotide binding protein 3" Q9NQE9 6 125956770-125980244 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 112.8" "Cell type enhanced" "Detected in all" "Early spermatids: 352.2;Spermatocytes: 110.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027914 Approved Approved Nucleoli,Mitochondria,Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 80: Striated muscle - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoli, Mitochondria" Cytosol "HPA027914: AB_10602424" "prognostic unfavorable (4.99e-4)" "unprognostic (4.75e-3)" "unprognostic (3.75e-2)" "unprognostic (1.29e-1)" "unprognostic (1.59e-1)" "unprognostic (1.71e-1)" "unprognostic (1.74e-1)" "unprognostic (4.88e-3)" "unprognostic (3.82e-1)" "unprognostic (1.27e-1)" "unprognostic (2.18e-2)" "unprognostic (1.05e-1)" "prognostic favorable (1.05e-6)" "unprognostic (4.09e-2)" "unprognostic (4.76e-2)" "unprognostic (9.56e-2)" "unprognostic (1.64e-1)" 18.1 23.4 31.2 12.6 33.9 12.3 23.0 31.0 43.3 18.3 22.8 19.6 15.7 16.6 17.8 22.3 16.4 16.2 28.4 29.4 31.4 22.2 28.3 21.0 11.3 33.9 32.1 14.7 19.3 30.6 14.4 14.5 33.8 29.7 17.6 15.3 25.5 22.4 112.8 17.5 16.0 17.3 36.6 10.5 24.8 12.3 32.5 13.6 23.5 84.6 11.4 18.4 10.8 38.0 13.2 10.3 14.1 29.5 5.5 14.8 17.5 14.1 20.2 10.6 11.0 25.6 7.2 28.4 25.5 9.4 23.7 19.5 18.2 11.9 12.3 27.4 23.5 12.0 15.1 21.6 25.4 19.2 19.6 11.8 25.9 10.7 27.0 27.3 16.1 21.0 38.3 18.7 10.6 20.1 15.5 13.7 4.8 27.1 9.9 12.8 9.7 9.7 21.8 24.0 28.2 17.4 12.9 18.0 67.8 10.2 18.4 28.9 11.4 7.2 10.1 34.8 20.3 27.1 33.3 18.2 20.4 18.1 9.5 12.5 9.3 8.9 4.4 5.9 4.6 7.0 5.9 4.8 7.7 6.3 6.0 5.3 11.2 5.9 8.6 4.3 6.3 5.3 31.2 33.9 31.0 43.3 29.4 31.4 33.9 32.1 33.8 36.6 32.5 38.0 11.7 80.1 61.2 11.8 16.7 18.1 10.2 22.1 24.5 21.8 26.5 18.4 38.7 10.0 29.8 16.5 8.4 19.2 13.4 17.2 33.2 29.3 352.2 23.6 11.5 12.3 16.3 6.9 27.0 20.2 6.4 13.7 19.4 25.8 9.5 15.2 10.4 17.5 27.2 6.7 29.8 25.1 20.3 15.3 14.6 78.3 9.9 19.3 21.4 5.6 17.3 43.4 11.3 21.6 40.0 21.4 28.7 17.3 8.1 20.9 15.3 28.0 25.7 25.4 6.6 18.3 15.1 110.7 40.2 21.5 17.3 26.4 11.3 14.6 18.5 19.9 HMGCS2 ENSG00000134240 "3-hydroxy-3-methylglutaryl-CoA synthase 2" P54868 1 119748002-119768905 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 2434.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 327.2;Hepatocytes: 1118.3;Intestinal goblet cells: 226.8;Paneth cells: 177.7;Undifferentiated cells: 282.3" "Cancer enriched" "Detected in many" 5 "liver cancer: 441.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "OE19: 113.6;RT4: 201.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027423, HPA027442, CAB032906" Enhanced Approved Mitochondria NA NA 830000 "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 2: Hepatocytes - Metabolism" Mitochondria "CAB032906: AB_2118322, HPA027423: AB_2672266, HPA027442: AB_2672277" "unprognostic (2.57e-1)" "unprognostic (1.12e-1)" "unprognostic (3.93e-2)" "unprognostic (7.62e-2)" "unprognostic (1.49e-2)" "prognostic favorable (2.43e-7)" "unprognostic (9.68e-2)" "unprognostic (3.21e-2)" "prognostic favorable (2.17e-4)" "unprognostic (1.20e-1)" "unprognostic (6.42e-2)" "prognostic favorable (3.43e-5)" "unprognostic (9.57e-2)" "unprognostic (2.31e-1)" "unprognostic (5.00e-2)" "unprognostic (1.54e-3)" 1.0 0.3 0.0 7.3 0.0 0.0 222.4 0.0 0.0 0.1 5.2 366.7 165.6 1.4 0.4 4.3 0.4 4.3 36.6 0.0 0.1 64.9 2434.1 2.2 0.1 0.0 0.1 0.1 20.1 0.1 0.1 0.4 0.0 34.0 228.0 0.1 50.8 0.6 6.9 14.2 151.8 23.7 0.0 0.6 101.2 35.6 0.0 0.4 0.6 3.1 0.0 36.5 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 12.9 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.2 113.6 0.1 0.2 0.7 0.7 0.0 201.6 0.1 0.8 0.6 0.0 0.0 0.1 7.6 0.0 0.0 0.0 0.5 0.1 0.0 0.2 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.2 10.8 0.0 2.4 0.1 3.7 0.0 1.2 0.0 18.8 5.6 8.7 42.9 0.1 31.3 0.0 0.8 0.0 327.2 0.0 0.0 1.9 0.6 0.1 1.1 73.1 24.0 0.0 0.0 0.2 0.2 66.8 1.4 4.5 19.5 16.4 1118.3 0.2 0.0 0.0 226.8 0.0 26.1 0.7 3.9 1.5 0.2 5.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 177.7 0.0 0.0 6.3 12.4 0.9 0.0 0.0 6.6 0.0 0.1 0.4 0.5 1.9 0.3 9.4 2.2 0.1 282.3 26.5 HNRNPLL HNRPLL ENSG00000143889 "Heterogeneous nuclear ribonucleoprotein L like" Q8WVV9 2 38561969-38603586 "Predicted intracellular proteins" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 155.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046084 Approved Approved Nucleoplasm,Mitochondria,Cytosol No No "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Mitochondria, Cytosol" "HPA046084: AB_10960895" "unprognostic (2.27e-2)" "unprognostic (1.75e-1)" "unprognostic (3.63e-2)" "unprognostic (5.18e-1)" "unprognostic (2.10e-3)" "unprognostic (1.43e-1)" "prognostic unfavorable (1.22e-4)" "unprognostic (1.52e-2)" "unprognostic (1.52e-1)" "unprognostic (1.80e-1)" "unprognostic (4.20e-2)" "unprognostic (1.01e-1)" "unprognostic (1.53e-1)" "unprognostic (2.25e-1)" "unprognostic (2.28e-1)" "unprognostic (1.26e-1)" "unprognostic (9.30e-2)" 16.0 16.4 16.3 12.5 20.7 51.7 14.7 19.3 21.3 16.2 12.9 16.1 15.5 18.2 13.9 10.2 16.7 14.1 12.8 28.6 8.3 11.1 10.8 16.4 12.5 5.9 8.1 16.9 15.9 16.8 9.2 13.1 7.2 13.9 11.8 26.6 12.8 15.0 13.8 11.4 12.7 12.8 7.8 12.0 15.7 22.6 9.3 31.0 17.7 11.9 9.6 15.2 12.8 15.8 36.7 16.9 48.2 28.4 22.9 21.6 30.1 33.8 27.5 28.8 24.1 19.0 20.7 0.5 29.5 30.4 30.9 23.0 30.7 25.4 29.6 54.6 26.8 26.7 32.3 48.6 21.6 49.9 26.4 16.9 19.6 24.0 26.5 28.5 30.6 23.9 45.9 79.7 34.3 17.2 54.9 27.2 48.4 35.2 30.6 10.6 33.9 18.1 25.0 47.2 32.9 36.9 29.8 25.8 26.0 26.7 21.8 21.6 32.0 21.5 32.1 23.8 28.1 43.4 46.9 0.3 18.5 12.2 26.8 10.6 6.3 9.7 10.3 3.2 17.9 0.4 24.2 18.9 12.0 1.9 7.2 4.6 4.2 6.8 1.2 0.2 38.5 5.8 16.3 20.7 19.3 21.3 28.6 8.3 5.9 8.1 7.2 7.8 9.3 15.8 17.0 19.2 23.4 26.8 5.5 28.7 35.2 16.5 33.0 13.3 18.0 15.2 18.8 8.6 18.8 27.6 8.4 26.2 6.4 13.9 19.6 22.4 155.6 18.1 18.8 20.1 14.4 22.5 68.6 24.3 28.9 26.0 32.1 11.6 9.5 26.3 22.5 7.4 24.4 6.7 40.1 15.4 6.1 15.0 90.2 48.7 27.7 23.1 39.2 37.5 24.5 22.3 2.1 48.7 28.4 21.2 14.2 52.3 23.0 23.6 16.6 18.6 14.5 11.7 39.5 22.6 28.4 91.1 28.8 19.4 21.3 22.2 48.0 22.3 18.8 21.4 HRNR "FLG3, S100A16, S100a18" ENSG00000197915 Hornerin Q86YZ3 1 152212076-152224193 "Plasma proteins, Predicted intracellular proteins" Keratinization "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.9" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 1.0;Horizontal cells: 1.7;Rod photoreceptor cells: 3.5" "Cancer enriched" "Detected in single" 4 "melanoma: 1.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NTERA-2: 1.9" "Not detected" "Not detected" HPA031469 Uncertain Approved Mitochondria No No 180000000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 46: Photoreceptor cells - Phototransduction" Mitochondria "HPA031469: AB_10603771" "unprognostic (1.34e-1)" "unprognostic (4.51e-2)" "unprognostic (3.01e-2)" "unprognostic (8.72e-4)" "unprognostic (1.61e-2)" "unprognostic (1.45e-1)" "unprognostic (2.11e-1)" "unprognostic (1.79e-1)" "unprognostic (6.09e-2)" "unprognostic (3.38e-2)" "unprognostic (1.87e-2)" "unprognostic (1.59e-2)" "unprognostic (1.65e-2)" "unprognostic (2.49e-2)" "unprognostic (1.71e-1)" "unprognostic (2.07e-1)" "unprognostic (3.64e-2)" 0.1 0.2 0.9 0.0 0.4 0.0 0.1 0.0 0.6 0.2 0.3 0.1 0.0 0.2 0.0 0.5 0.2 0.0 0.2 0.4 1.9 0.3 0.1 0.1 0.0 1.8 0.7 0.4 0.4 0.0 0.2 0.0 1.1 0.2 0.0 0.3 0.1 0.0 0.0 0.6 0.1 0.0 0.3 0.1 0.1 0.4 0.7 0.0 0.3 0.0 0.0 0.1 0.2 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.4 0.0 0.4 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.4 0.0 0.6 0.4 1.9 1.8 0.7 1.1 0.3 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 HS2ST1 KIAA0448 ENSG00000153936 "Heparan sulfate 2-O-sulfotransferase 1" Q7LGA3 1 86914635-87109982 "Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 160.9;Excitatory neurons: 126.1;Inhibitory neurons: 130.1;Oligodendrocyte precursor cells: 95.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "HPA043069, HPA043603, HPA075001" Supported Approved Mitochondria "Intracellular and membrane" No No "Cluster 38: Basophils - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "HPA043069: AB_10964127, HPA043603: AB_10963432, HPA075001: AB_2686726" "unprognostic (1.04e-1)" "unprognostic (1.50e-1)" "unprognostic (1.28e-3)" "unprognostic (8.06e-2)" "unprognostic (1.87e-1)" "unprognostic (7.13e-2)" "prognostic unfavorable (6.88e-4)" "unprognostic (7.20e-2)" "unprognostic (5.34e-2)" "unprognostic (7.70e-2)" "unprognostic (1.70e-3)" "unprognostic (1.45e-1)" "unprognostic (5.80e-2)" "unprognostic (1.63e-2)" "unprognostic (5.07e-2)" "unprognostic (3.24e-1)" "unprognostic (7.58e-2)" 8.0 25.7 11.5 9.4 13.8 3.8 8.1 8.0 12.2 10.5 13.2 9.3 9.7 9.1 9.9 7.0 6.7 10.6 7.0 11.9 11.4 13.8 17.2 8.2 11.8 10.1 11.0 12.7 10.1 13.4 6.6 8.3 8.1 9.5 9.0 19.3 6.7 9.9 4.4 8.2 9.3 7.8 8.8 12.7 8.3 9.3 12.2 10.6 12.9 4.7 11.6 9.4 5.9 8.4 24.4 20.4 59.0 38.5 31.9 92.3 20.4 23.3 30.5 19.2 21.2 78.1 30.6 53.3 22.1 16.4 33.2 14.5 27.2 19.5 30.8 42.1 22.2 64.0 21.0 63.0 13.4 33.6 31.0 38.2 17.0 31.0 25.6 30.4 28.8 29.7 44.6 27.4 28.1 8.6 33.8 20.2 19.8 26.5 12.9 41.2 55.7 11.6 23.5 50.3 12.6 19.0 30.6 26.2 27.2 15.2 17.2 15.2 25.7 24.0 29.8 42.2 29.7 25.1 19.9 49.7 14.8 23.6 25.0 6.2 1.1 1.0 1.3 0.6 1.6 1.1 1.5 1.5 0.7 2.8 1.4 0.9 1.2 1.1 2.8 0.7 0.9 1.0 11.5 13.8 8.0 12.2 11.9 11.4 10.1 11.0 8.1 8.8 12.2 8.4 13.0 16.0 12.4 160.9 14.2 16.6 8.6 9.3 19.9 10.9 11.9 7.6 12.8 14.3 15.2 20.2 4.2 8.2 5.7 13.5 13.7 18.2 5.5 7.1 23.6 13.8 23.4 12.2 126.1 11.5 9.3 16.9 11.2 8.0 19.0 74.2 18.2 28.9 37.7 8.4 130.1 12.5 18.3 12.8 13.5 3.8 6.8 15.3 12.4 53.4 8.2 28.8 5.2 95.0 54.5 11.3 7.7 20.3 24.0 7.3 17.6 18.3 11.2 17.7 0.0 21.1 16.8 10.1 15.0 12.8 15.8 4.4 12.9 77.4 13.5 7.1 HSPBAP1 "FLJ22623, PASS1" ENSG00000169087 "HSPB1 associated protein 1" Q96EW2 3 122739999-122793831 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 60.5;Microglial cells: 52.5;Syncytiotrophoblasts: 48.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044930 Approved Approved Mitochondria NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 23: Testis - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "HPA044930: AB_10961122" "unprognostic (3.40e-3)" "unprognostic (1.22e-2)" "unprognostic (2.98e-2)" "unprognostic (6.70e-3)" "unprognostic (3.40e-3)" "unprognostic (3.40e-2)" "unprognostic (8.61e-4)" "unprognostic (2.68e-2)" "unprognostic (6.95e-2)" "unprognostic (3.35e-2)" "unprognostic (2.36e-1)" "unprognostic (8.91e-2)" "unprognostic (1.24e-3)" "unprognostic (4.29e-1)" "unprognostic (1.33e-1)" "unprognostic (3.34e-1)" "unprognostic (4.12e-3)" 4.2 5.4 2.9 4.3 3.3 3.1 3.8 3.4 4.2 3.8 4.1 3.7 2.5 3.8 1.9 2.8 3.1 3.5 3.2 3.3 3.5 4.3 3.5 4.6 6.2 4.0 3.4 3.0 3.8 3.7 2.7 6.0 4.0 3.3 3.4 4.6 3.2 3.2 15.9 4.3 3.8 3.8 3.4 7.3 3.0 10.7 3.4 6.4 6.2 8.7 5.5 4.3 3.2 3.9 5.4 4.1 5.8 5.2 6.8 5.1 11.3 2.6 6.7 6.1 8.6 5.6 4.1 6.9 4.2 1.8 15.4 6.4 9.0 5.0 7.1 4.3 2.5 4.6 4.8 3.3 15.4 4.2 6.1 7.7 18.0 5.1 16.3 5.8 5.8 6.9 3.1 5.8 5.6 3.5 6.1 5.3 6.6 4.2 8.2 6.2 7.8 6.8 6.4 2.1 6.4 6.5 6.2 2.4 23.3 5.5 2.9 8.8 5.8 7.1 4.2 2.3 3.7 5.7 6.1 8.1 4.4 6.2 7.1 23.0 16.5 12.0 6.1 12.2 7.6 11.0 8.0 6.1 13.0 8.3 8.6 8.4 30.6 6.3 24.1 4.5 10.3 8.2 2.9 3.3 3.4 4.2 3.3 3.5 4.0 3.4 4.0 3.4 3.4 3.9 10.2 6.4 5.3 10.7 20.8 10.7 3.9 5.0 6.8 6.6 3.9 5.7 5.7 4.3 3.9 5.5 60.5 16.8 11.4 4.9 3.9 5.5 35.7 7.3 5.1 6.4 0.0 7.2 15.2 6.0 11.0 6.5 5.6 4.4 6.3 6.4 11.0 3.6 12.9 8.4 24.7 3.1 4.1 24.1 14.1 8.0 9.6 20.1 5.4 52.5 29.4 3.7 14.4 8.0 22.9 4.3 3.5 4.9 6.4 3.2 6.3 4.5 5.9 12.8 6.6 7.1 4.9 36.8 8.4 5.0 7.5 48.6 10.3 7.4 3.5 1.7 ICA1L "ALS2CR14, ALS2CR15" ENSG00000163596 "Islet cell autoantigen 1 like" Q8NDH6 2 202773150-202871766 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 171.7;Inhibitory neurons: 114.3;Oligodendrocyte precursor cells: 93.5;Rod photoreceptor cells: 84.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 21.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042507 Approved Approved Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 58: Brain - Synaptic function" "Cluster 28: BEWO - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Mitochondria "HPA042507: AB_10797016" "unprognostic (4.14e-3)" "unprognostic (3.60e-3)" "unprognostic (5.15e-2)" "unprognostic (5.63e-3)" "unprognostic (1.96e-1)" "unprognostic (2.36e-1)" "unprognostic (1.38e-1)" "unprognostic (8.05e-4)" "unprognostic (1.66e-1)" "unprognostic (9.60e-2)" "unprognostic (4.50e-4)" "unprognostic (4.15e-1)" "unprognostic (8.15e-3)" "unprognostic (2.97e-2)" "unprognostic (1.74e-1)" "unprognostic (9.79e-2)" "unprognostic (1.58e-3)" 3.8 4.8 9.8 1.3 12.0 3.9 3.5 23.2 20.6 7.1 7.4 6.8 1.5 7.5 5.7 2.6 9.5 3.6 4.9 13.4 13.7 3.2 0.5 2.2 1.5 3.7 5.5 8.1 2.7 7.1 15.7 5.2 1.6 5.5 1.6 17.5 1.9 6.1 5.1 1.9 2.0 4.6 3.3 1.4 3.7 8.3 9.9 2.7 5.1 6.7 1.2 5.4 3.4 8.7 1.5 1.2 2.9 8.4 2.7 5.0 21.8 2.9 3.8 1.6 2.3 1.4 0.6 1.7 0.8 3.5 4.6 0.8 4.0 1.4 2.1 1.5 3.1 3.6 1.8 1.8 1.5 4.4 2.1 1.9 2.4 1.7 1.4 4.9 2.4 5.6 2.8 1.6 2.5 0.7 3.6 6.0 8.4 0.5 3.1 4.3 4.4 0.7 1.6 3.9 7.8 7.5 4.5 0.2 1.9 2.4 1.0 3.4 1.6 7.0 1.8 1.5 4.4 5.5 8.9 4.5 4.0 1.4 1.3 1.2 1.1 0.6 0.9 1.2 0.7 1.3 0.8 0.7 1.6 2.3 1.1 1.6 1.5 2.3 2.1 1.1 0.7 0.7 9.8 12.0 23.2 20.6 13.4 13.7 3.7 5.5 1.6 3.3 9.9 8.7 13.0 9.6 10.0 62.0 10.5 2.0 4.4 2.9 1.2 58.7 4.1 2.8 15.2 1.5 8.7 18.4 60.5 16.3 5.7 1.0 0.0 5.3 28.7 40.9 17.0 5.8 19.2 2.5 171.7 4.9 37.7 12.0 3.6 9.9 6.3 17.4 5.7 1.1 3.6 16.8 114.3 2.1 4.1 5.3 9.7 40.2 31.7 5.2 7.2 15.9 3.8 22.1 17.5 93.5 42.7 3.4 0.6 46.3 2.1 5.2 1.9 3.7 36.7 84.1 0.0 10.0 6.3 34.1 8.8 1.9 2.3 7.5 7.3 6.0 1.7 2.7 ICAM3 "CD50, CDW50, ICAM-R" ENSG00000076662 "Intercellular adhesion molecule 3" P32942 19 10333776-10339661 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 206.5;liver: 73.2;lymphoid tissue: 85.8" "Cell type enhanced" "Detected in many" "B-cells: 151.9;dendritic cells: 164.6;Hepatocytes: 168.8;NK-cells: 313.1;Plasma cells: 137.2;T-cells: 183.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1948.5" "Lineage enriched" "Detected in all" 4 "granulocytes: 1948.5" "Cell line enhanced" "Detected in many" "Karpas-707: 324.6;NB-4: 222.3;RPMI-8226: 257.6;U-266/84: 188.8;U-937: 179.0" "Not detected" "Not detected" "CAB002498, HPA049820" Enhanced Approved "Nucleoplasm,Nuclear membrane,Mitochondria" NA NA 390000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Mitochondria "Nucleoplasm, Nuclear membrane" "CAB002498: AB_563593, HPA049820: AB_2680897" "unprognostic (6.85e-4)" "unprognostic (5.28e-3)" "unprognostic (3.09e-3)" "unprognostic (1.57e-2)" "unprognostic (5.34e-3)" "unprognostic (5.79e-6)" "unprognostic (5.05e-3)" "unprognostic (3.73e-2)" "unprognostic (1.73e-3)" "unprognostic (7.93e-2)" "unprognostic (3.45e-2)" "unprognostic (2.54e-1)" "unprognostic (5.62e-4)" "unprognostic (1.13e-1)" "unprognostic (1.06e-2)" "unprognostic (3.43e-1)" "unprognostic (1.84e-1)" 18.9 7.4 4.8 50.4 4.6 206.5 10.0 4.5 6.4 4.9 4.4 16.1 15.1 3.6 2.8 7.6 6.2 9.0 18.1 4.5 4.6 11.9 73.2 16.0 72.2 4.9 5.0 2.9 15.2 2.9 1.0 4.6 5.0 6.8 11.0 0.9 15.2 2.9 18.0 4.3 28.1 4.4 5.2 85.8 19.5 2.1 5.2 48.6 6.8 11.9 50.6 14.1 4.4 4.6 12.4 5.8 4.2 13.1 6.8 5.3 7.3 7.5 5.1 5.9 5.2 5.3 8.1 0.2 24.9 6.2 0.1 5.4 0.2 5.5 2.0 106.2 3.7 23.8 5.4 22.6 3.4 96.7 102.1 4.8 4.4 7.0 2.6 6.4 2.9 57.1 13.0 324.6 6.9 24.0 13.9 222.3 3.2 31.7 38.3 11.1 2.7 257.6 6.2 11.2 1.3 5.6 6.5 20.4 17.3 1.9 17.7 23.9 4.6 28.0 3.0 31.2 7.6 20.7 188.8 37.3 20.2 179.0 22.1 193.6 395.4 872.4 362.7 287.8 436.2 280.1 343.0 331.7 327.5 271.7 301.5 283.9 1948.5 380.1 417.4 52.9 436.3 614.5 4.8 4.6 4.5 6.4 4.5 4.6 4.9 5.0 5.0 5.2 5.2 4.6 22.6 3.2 29.7 0.7 151.9 8.2 6.5 7.0 10.2 0.3 23.1 20.6 0.1 21.5 9.8 5.5 0.0 12.0 164.6 49.1 62.6 16.9 7.7 10.7 9.4 19.2 5.4 37.4 0.2 35.4 24.7 10.2 16.8 9.9 30.4 5.5 31.1 168.8 24.0 1.7 0.1 33.2 4.1 70.0 50.4 10.0 6.2 52.9 55.2 1.0 127.7 6.4 313.1 0.0 0.1 23.2 43.8 4.1 137.2 12.3 79.9 54.4 9.0 1.2 0.0 7.3 10.7 5.7 0.7 8.3 8.4 4.7 183.3 5.4 36.4 10.2 IDNK "bA522I20.2, C9orf103, hGntK" ENSG00000148057 "IDNK gluconokinase" Q5T6J7 9 83623049-83644130 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 70.5" "Cell type enhanced" "Detected in many" "Distal tubular cells: 80.3;Proximal enterocytes: 84.2;Proximal tubular cells: 224.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 26.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020378, HPA058429" Approved Approved Mitochondria,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Mitochondria, Cytosol" "HPA020378: AB_1845794, HPA058429: AB_2683716" "unprognostic (1.49e-3)" "unprognostic (7.94e-2)" "unprognostic (3.30e-1)" "prognostic favorable (1.10e-6)" "unprognostic (1.39e-1)" "unprognostic (1.56e-1)" "unprognostic (5.41e-3)" "unprognostic (1.81e-2)" "unprognostic (6.08e-2)" "unprognostic (1.57e-1)" "unprognostic (2.61e-2)" "unprognostic (3.00e-1)" "unprognostic (5.86e-3)" "unprognostic (7.32e-2)" "unprognostic (1.07e-1)" "unprognostic (2.55e-1)" "unprognostic (3.11e-2)" 8.9 12.0 18.8 6.1 24.5 5.8 8.7 20.6 26.8 4.3 22.7 9.5 26.3 5.3 13.3 8.3 12.9 6.4 5.8 19.1 22.6 50.9 70.5 7.3 11.0 20.3 20.8 5.5 13.8 14.8 9.0 3.0 20.6 8.4 9.2 10.9 8.8 9.5 2.3 7.1 26.9 4.4 20.5 7.9 8.9 3.7 20.8 38.9 13.2 2.6 9.5 5.2 3.9 21.1 4.3 10.4 1.7 1.8 4.6 6.9 7.8 3.4 8.6 3.5 2.8 2.9 5.3 5.8 5.2 5.8 3.5 8.4 1.3 2.0 3.6 11.9 1.6 2.1 4.6 12.7 19.4 1.5 2.8 4.3 3.3 7.2 7.2 6.2 7.9 16.0 1.9 7.1 4.8 26.8 3.7 1.4 1.6 18.1 6.0 4.6 4.2 3.3 9.6 5.5 6.9 8.6 7.5 6.5 7.6 2.5 6.0 8.1 7.4 1.6 1.3 14.3 6.1 9.0 10.4 1.0 7.3 2.4 2.8 100.7 13.0 19.1 30.5 24.1 25.4 39.3 26.0 24.7 18.1 26.7 20.2 27.2 2.8 33.1 47.6 20.9 52.2 24.8 18.8 24.5 20.6 26.8 19.1 22.6 20.3 20.8 20.6 20.5 20.8 21.1 6.2 12.8 8.7 14.7 9.3 6.8 3.2 7.3 4.0 8.9 10.0 8.4 9.9 10.0 8.8 5.5 0.0 8.0 11.3 8.4 80.3 11.3 0.4 34.6 2.0 5.6 7.3 2.5 4.7 16.1 4.6 8.0 4.6 7.0 20.8 10.2 3.3 44.3 11.1 10.1 5.6 12.8 12.2 11.6 7.5 2.0 4.4 8.2 12.4 11.2 19.8 38.0 24.7 8.0 11.4 5.4 21.7 4.1 12.1 4.6 84.2 224.4 28.3 3.5 0.0 8.8 5.9 1.4 1.5 5.4 5.8 3.0 13.7 9.9 11.2 4.2 IDO1 "IDO, INDO" ENSG00000131203 "Indoleamine 2,3-dioxygenase 1" P14902 8 39902275-39928790 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Immunity, Tryptophan catabolism" "Dioxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 58.7;placenta: 110.9" "Cell type enriched" "Detected in many" 11 "monocytes: 2612.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 14 "eosinophil: 465.0" "Lineage enriched" "Detected in many" 18 "granulocytes: 465.0" "Cell line enriched" "Detected in some" 7 "EFO-21: 61.8" "Region enriched" "Detected in many" 12 "basal ganglia: 34.1" "Low region specificity" "Detected in all" "HPA023072, HPA023149, HPA027772, CAB072820" Enhanced Supported Nucleoplasm,Vesicles,Mitochondria,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 38: EFO-21 - Unknown function" "Cluster 3: Monocytes - Immune response regulation" Cytosol "Nucleoplasm, Vesicles, Mitochondria" "CAB072820: , HPA023072: AB_1846220, HPA023149: AB_1846221, HPA027772: AB_1846222" "unprognostic (1.68e-2)" "unprognostic (1.71e-2)" "unprognostic (4.08e-3)" "unprognostic (7.21e-3)" "unprognostic (1.90e-1)" "unprognostic (1.09e-2)" "unprognostic (1.86e-1)" "unprognostic (3.06e-2)" "prognostic favorable (5.27e-4)" "prognostic favorable (3.32e-4)" "unprognostic (3.59e-2)" "unprognostic (2.74e-1)" "prognostic unfavorable (1.12e-7)" "unprognostic (4.18e-2)" "unprognostic (4.42e-2)" "unprognostic (1.16e-1)" "unprognostic (1.97e-2)" 9.8 0.7 0.6 40.5 0.4 0.7 2.0 0.4 0.8 7.2 1.0 5.3 10.3 10.2 1.2 1.3 2.6 6.2 1.8 0.4 0.6 1.7 2.4 25.9 58.7 0.7 0.3 1.2 1.2 0.2 0.1 110.9 0.5 2.0 8.2 1.3 1.9 3.0 8.1 1.3 8.4 2.4 0.4 23.0 5.8 1.1 0.8 31.2 4.0 0.6 31.5 9.1 0.5 0.6 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.9 7.6 4.8 0.3 0.8 0.0 61.8 0.0 3.3 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.1 0.4 0.1 0.0 0.0 0.2 0.0 0.3 0.4 0.1 0.0 0.1 0.0 0.1 0.0 0.1 8.4 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 2.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 9.1 0.2 0.2 0.0 0.3 0.0 32.5 1.3 465.0 0.1 1.4 0.1 0.2 0.1 0.0 26.4 0.3 0.1 0.2 4.9 0.1 0.1 0.3 0.1 1.2 0.6 0.4 0.4 0.8 0.4 0.6 0.7 0.3 0.5 0.4 0.8 0.6 24.9 0.0 0.5 0.7 4.4 0.4 0.2 18.3 0.0 0.0 0.5 0.1 0.3 0.0 76.0 0.0 0.0 0.0 0.3 8.3 0.0 4.4 3.7 70.1 23.0 6.9 0.0 0.0 0.2 8.1 0.0 0.3 0.0 223.3 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 2.0 3.7 28.1 1.8 0.0 13.6 0.0 0.0 2612.3 3.0 0.0 0.0 0.1 0.4 0.0 0.4 2.4 0.5 0.0 0.0 33.3 0.2 0.0 1.2 8.4 0.0 0.1 0.1 0.6 0.0 1.3 0.0 1.3 2.0 IFI6 "6-16, FAM14C, G1P3, IFI-6-16, IFI616" ENSG00000126709 "Interferon alpha inducible protein 6" P09912 1 27666064-27672212 "Predicted membrane proteins" "Antiviral defense, Apoptosis, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Cytotrophoblasts: 4084.0;Extravillous trophoblasts: 1291.2;Syncytiotrophoblasts: 4273.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 1349.9;BJ hTERT+ SV40 Large T+ RasG12V: 1570.7;EFO-21: 544.1;SK-MEL-30: 1075.0" "Low region specificity" "Detected in all" HPA005543 Approved Approved Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA005543: AB_1849342" "unprognostic (4.31e-1)" "unprognostic (1.03e-1)" "unprognostic (1.54e-1)" "unprognostic (1.04e-1)" "unprognostic (2.70e-1)" "unprognostic (6.96e-2)" "unprognostic (9.21e-2)" "unprognostic (1.07e-1)" "unprognostic (3.06e-1)" "unprognostic (6.77e-3)" "unprognostic (5.04e-2)" "unprognostic (1.64e-2)" "unprognostic (1.92e-3)" "unprognostic (1.81e-1)" "unprognostic (8.40e-2)" "unprognostic (3.42e-2)" "unprognostic (1.72e-2)" 84.0 161.4 117.5 37.5 142.0 113.2 73.1 106.8 159.3 99.7 164.7 76.3 44.0 55.6 39.1 30.5 49.6 56.8 114.2 126.4 168.7 154.1 135.6 143.5 14.9 200.8 145.5 81.4 57.2 116.0 316.7 298.2 155.6 60.6 24.5 17.2 334.3 23.0 23.8 35.3 52.1 43.6 299.5 91.0 96.1 61.9 153.1 62.2 166.9 20.1 14.5 43.8 47.4 139.2 15.6 4.4 22.7 14.1 72.4 38.8 90.6 48.5 220.1 1349.9 1570.7 8.0 58.5 6.1 544.1 22.1 352.4 5.2 5.5 10.8 43.7 117.3 18.4 36.4 11.2 4.8 19.4 12.4 45.1 43.3 1.8 82.1 1.1 20.9 12.6 31.6 2.5 95.2 15.3 4.4 44.1 153.4 4.4 28.7 46.4 29.6 12.1 14.9 12.2 0.9 32.2 28.8 59.9 13.6 1075.0 6.7 6.9 46.5 21.7 12.6 19.3 9.4 8.4 113.5 68.1 4.4 24.6 105.3 35.8 193.3 265.8 252.0 128.7 374.6 127.9 57.3 128.2 118.0 117.6 47.0 132.7 130.9 506.8 102.0 259.4 12.8 172.9 113.2 117.5 142.0 106.8 159.3 126.4 168.7 200.8 145.5 155.6 299.5 153.1 139.2 158.0 141.1 74.4 5.2 26.1 23.5 19.8 39.3 29.0 15.2 17.5 14.4 12.9 54.3 42.2 64.4 10.4 4084.0 44.7 13.2 19.6 244.0 3.4 61.4 76.4 194.8 58.4 27.6 3.6 340.0 1291.2 149.3 21.4 91.8 63.3 186.3 82.8 40.4 685.3 3.3 7.4 60.5 67.1 71.8 49.1 11.5 110.6 169.4 71.2 24.4 93.8 95.1 46.4 16.1 3.9 214.2 11.7 204.7 96.0 48.2 16.9 32.7 89.3 5.6 111.7 60.9 63.1 7.9 1.6 5.8 22.4 4273.1 59.6 138.6 13.0 49.0 IFT57 "ESRRBL1, FLJ10147, HIPPI, MHS4R2" ENSG00000114446 "Intraflagellar transport 57" Q9NWB7 3 108160812-108222435 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" DNA-binding Ciliopathy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 1675.3;Late spermatids: 2795.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 41.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035514, HPA035515" Supported Approved "Nuclear speckles,Mitochondria,Cytosol" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 34: Spermatids - Unknown function" "Nuclear speckles" "Mitochondria, Cytosol" "HPA035514: AB_10601757, HPA035515: AB_10696505" "unprognostic (1.35e-2)" "unprognostic (1.37e-2)" "prognostic favorable (6.96e-5)" "unprognostic (2.98e-2)" "unprognostic (5.46e-3)" "unprognostic (1.02e-2)" "unprognostic (3.79e-2)" "unprognostic (3.61e-3)" "unprognostic (3.59e-2)" "prognostic favorable (7.63e-4)" "unprognostic (5.04e-2)" "unprognostic (2.78e-1)" "unprognostic (1.68e-3)" "unprognostic (1.86e-1)" "unprognostic (4.70e-2)" "unprognostic (8.67e-3)" "unprognostic (6.12e-2)" 8.9 15.3 11.6 8.6 11.7 13.2 13.1 10.2 15.5 11.7 14.8 13.3 6.0 13.3 45.1 8.5 32.0 13.4 10.4 11.4 11.5 21.3 4.5 40.7 17.3 12.0 12.2 14.0 13.8 23.0 16.3 7.8 11.6 27.5 14.6 24.0 9.1 17.5 4.2 8.6 9.0 10.6 11.9 12.1 9.8 42.8 12.0 8.2 26.1 4.4 16.4 13.9 8.3 11.8 35.5 17.2 12.8 23.1 26.1 26.9 7.1 10.6 25.8 15.3 13.6 12.4 6.1 39.5 13.3 17.8 22.0 13.9 11.5 17.8 25.8 6.2 12.2 13.6 8.0 3.3 19.4 28.5 30.2 16.3 16.1 19.9 34.2 24.4 17.5 6.6 6.4 6.9 17.8 18.9 9.5 25.8 13.6 2.7 21.0 6.1 11.5 6.3 31.6 12.3 21.1 14.7 15.9 5.2 9.9 7.1 11.0 8.3 7.5 19.6 10.2 10.5 12.6 8.1 6.2 20.7 28.4 2.7 7.3 0.2 3.5 3.1 3.6 6.5 5.8 41.9 7.4 4.5 10.2 34.9 6.2 3.7 1.8 6.8 12.8 2.0 5.1 4.9 11.6 11.7 10.2 15.5 11.4 11.5 12.0 12.2 11.6 11.9 12.0 11.8 36.6 471.1 291.2 18.6 98.4 41.0 114.1 72.9 34.7 25.6 42.2 50.9 33.8 58.6 201.9 51.5 68.8 22.3 16.9 51.1 117.4 158.8 1675.3 266.3 57.8 38.2 57.2 13.7 52.6 134.1 19.3 78.9 25.5 37.0 44.3 57.1 25.7 5.9 14.5 28.6 20.3 35.7 42.7 8.1 27.7 2795.4 65.3 19.3 46.2 4.7 13.1 56.8 8.2 13.0 13.5 79.4 36.6 64.3 40.2 151.4 24.3 124.5 528.7 72.7 52.6 61.7 61.3 242.2 43.6 25.4 37.2 14.9 30.2 104.9 52.3 93.0 IGSF22 "FLJ37794, IGFN2" ENSG00000179057 "Immunoglobulin superfamily member 22" Q8N9C0 11 18704312-18726230 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "skin 1: 1.0" "Cell type enhanced" "Detected in many" "Collecting duct cells: 23.9;Distal tubular cells: 21.5" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB026459, HPA037851" Uncertain Approved Mitochondria NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB026459: , HPA037851: " "unprognostic (4.05e-2)" "unprognostic (3.65e-2)" "unprognostic (2.34e-2)" "unprognostic (1.84e-1)" "unprognostic (1.23e-1)" "unprognostic (8.93e-2)" "unprognostic (1.02e-1)" "unprognostic (8.38e-2)" "unprognostic (8.70e-2)" "unprognostic (4.24e-2)" "unprognostic (1.99e-4)" "unprognostic (9.35e-2)" "unprognostic (3.72e-4)" "unprognostic (2.87e-1)" "unprognostic (2.18e-1)" "unprognostic (3.43e-1)" "unprognostic (7.94e-3)" 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.3 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.2 1.0 0.1 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.3 0.2 0.3 0.1 0.1 0.1 0.0 0.3 0.2 0.6 0.0 0.5 0.3 2.9 2.4 4.7 1.4 0.6 1.3 7.5 5.3 1.7 0.0 3.1 23.9 0.0 0.0 1.0 1.5 21.5 3.3 1.4 5.3 1.2 0.9 3.6 0.0 3.2 4.3 0.0 0.7 2.0 5.8 2.5 0.7 0.4 0.4 1.5 1.7 1.7 5.8 8.2 0.3 1.0 4.6 1.5 0.6 0.0 0.0 0.7 0.5 2.1 1.5 0.3 9.5 2.6 0.7 0.3 4.0 0.3 2.2 6.1 0.9 0.0 0.5 1.0 0.0 0.4 0.7 1.7 0.0 2.9 3.1 2.8 8.4 IL18R1 "CD218a, IL-1Rrp, IL1RRP" ENSG00000115604 "Interleukin 18 receptor 1" Q13478 2 102311529-102398777 "CD markers, Enzymes, Plasma proteins, Predicted membrane proteins" "Inflammatory response" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 24.2;lymphoid tissue: 18.5" "Cell type enhanced" "Detected in many" "dendritic cells: 44.7;granulocytes: 111.2;Langerhans cells: 25.4;NK-cells: 42.2;T-cells: 25.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 45.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 27.4;HHSteC: 35.4;U-937: 52.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA007615 Approved Approved Mitochondria Yes No "Cluster 48: NK-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" Mitochondria "HPA007615: AB_1851675" "unprognostic (3.60e-3)" "unprognostic (9.75e-3)" "unprognostic (1.12e-3)" "unprognostic (3.01e-2)" "unprognostic (2.34e-3)" "unprognostic (7.11e-2)" "unprognostic (2.95e-2)" "unprognostic (1.74e-2)" "unprognostic (3.59e-1)" "unprognostic (7.86e-2)" "unprognostic (3.40e-2)" "unprognostic (1.70e-1)" "prognostic unfavorable (4.52e-4)" "unprognostic (2.62e-1)" "unprognostic (1.62e-2)" "unprognostic (5.71e-2)" "unprognostic (2.48e-2)" 8.2 2.3 1.3 5.6 1.4 2.4 5.4 1.2 1.9 4.5 1.6 4.0 4.1 3.1 1.6 2.2 3.7 2.9 4.5 1.0 2.4 4.4 6.6 24.2 4.1 1.5 1.3 1.1 1.3 3.2 1.7 6.9 1.8 3.3 1.0 0.2 2.2 5.7 0.9 2.6 8.8 0.7 1.3 18.5 4.3 0.5 2.0 2.0 2.1 1.1 2.2 4.0 2.8 1.3 1.8 0.6 0.0 0.0 1.3 0.8 2.3 0.0 1.1 0.1 0.5 0.0 0.8 0.0 0.1 0.0 3.4 0.9 0.0 2.4 0.0 27.4 1.2 2.1 0.5 0.1 35.4 8.8 10.1 7.8 1.9 3.1 5.4 0.0 7.4 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.1 1.4 1.1 0.0 0.0 0.0 0.3 0.9 0.0 0.0 1.2 0.1 0.3 0.1 0.0 0.0 0.8 0.9 0.5 3.2 0.6 0.0 0.0 0.0 0.1 52.0 3.6 10.0 0.0 4.8 6.2 0.1 16.3 0.1 3.6 4.7 3.6 0.2 0.6 1.4 6.7 45.6 0.0 10.4 4.1 1.9 1.3 1.4 1.2 1.9 1.0 2.4 1.5 1.3 1.8 1.3 2.0 1.3 10.2 0.0 8.5 0.3 2.7 0.8 1.1 1.1 0.6 0.0 0.3 0.3 3.9 0.0 2.3 1.8 0.0 0.0 44.7 0.3 1.9 0.9 0.1 1.0 4.1 7.4 0.0 3.6 0.2 0.6 1.0 3.1 5.1 1.1 111.2 0.0 10.0 7.6 0.1 0.0 1.0 0.1 0.0 2.4 25.4 0.1 0.3 16.5 3.6 12.2 1.0 0.2 42.2 1.5 0.0 1.1 0.4 0.0 10.3 1.0 0.1 0.9 3.8 0.2 6.6 0.9 1.4 0.4 1.3 0.3 1.0 0.0 25.4 0.1 0.4 0.9 IMMP2L "IMMP2L-IT1, IMP2" ENSG00000184903 "Inner mitochondrial membrane peptidase subunit 2" Q96T52 7 110662644-111562517 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Astrocytes: 247.8;Distal tubular cells: 160.4;Excitatory neurons: 365.4;Inhibitory neurons: 373.9;Microglial cells: 455.3;Oligodendrocyte precursor cells: 273.9;Oligodendrocytes: 233.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026711 Approved Approved Mitochondria NA NA "Cluster 24: B-cells - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA026711: AB_1851760" "unprognostic (2.55e-2)" "unprognostic (1.40e-2)" "unprognostic (4.29e-1)" "unprognostic (1.04e-1)" "unprognostic (3.76e-2)" "prognostic unfavorable (1.89e-5)" "unprognostic (5.64e-3)" "unprognostic (1.00e-1)" "unprognostic (4.17e-1)" "unprognostic (5.68e-3)" "unprognostic (1.12e-1)" "unprognostic (1.09e-1)" "unprognostic (2.89e-3)" "unprognostic (1.32e-1)" "unprognostic (6.65e-2)" "unprognostic (1.79e-1)" "unprognostic (2.71e-1)" 19.2 14.2 10.4 5.1 12.5 5.2 15.7 9.6 11.7 12.4 14.2 14.6 7.6 15.3 11.9 8.0 16.0 8.5 13.1 11.9 12.2 34.0 25.7 8.1 7.5 11.3 11.3 19.5 12.1 20.1 8.0 9.0 11.3 19.0 8.2 9.2 11.1 21.1 27.3 10.2 12.9 14.2 10.9 8.4 11.8 9.9 11.4 8.9 23.5 25.1 7.5 12.5 10.5 13.1 17.5 10.3 6.1 25.1 15.8 16.0 10.7 11.8 11.9 7.7 8.1 5.1 19.8 28.4 31.4 10.2 14.3 9.6 6.6 23.6 12.7 17.9 6.7 9.7 44.2 14.0 24.2 18.2 1.1 27.9 30.7 3.3 21.4 35.0 10.2 26.2 32.0 21.4 5.9 12.3 24.4 20.3 6.0 33.2 15.8 5.1 50.0 15.0 28.0 7.3 7.0 22.1 5.1 23.8 67.3 17.2 9.6 10.4 6.5 11.8 12.3 11.9 14.4 12.2 3.5 17.4 12.9 8.4 63.1 15.9 9.1 2.9 10.5 11.9 19.4 28.5 18.3 12.3 17.0 38.7 25.0 17.6 0.5 47.0 17.3 21.3 12.4 8.1 10.4 12.5 9.6 11.7 11.9 12.2 11.3 11.3 11.3 10.9 11.4 13.1 22.3 19.2 13.2 247.8 20.4 32.9 34.4 41.4 39.9 11.3 35.3 39.4 19.5 15.7 23.9 47.8 8.4 22.4 11.9 3.1 160.4 30.1 8.4 10.4 12.6 15.3 19.3 21.9 365.4 8.1 27.1 19.5 12.8 12.0 3.8 11.3 11.7 23.8 11.7 8.4 373.9 7.0 28.5 4.9 14.1 5.6 49.4 6.1 21.4 455.3 10.1 16.3 1.0 273.9 233.7 10.8 6.8 35.0 9.2 36.2 25.5 66.8 13.3 15.6 13.1 19.5 46.7 24.2 12.8 28.0 26.6 16.3 12.6 18.7 11.7 22.1 IMPA2 ENSG00000141401 "Inositol monophosphatase 2" O14732 18 11981025-12030877 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 359.1;skeletal muscle: 257.1" "Cell type enhanced" "Detected in many" "Distal tubular cells: 440.3;Extravillous trophoblasts: 272.2;Proximal tubular cells: 498.6;Squamous epithelial cells: 202.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 26.0;neutrophil: 31.3" "Group enriched" "Detected in many" 11 "dendritic cells: 9.0;granulocytes: 31.3;monocytes: 11.4" "Cell line enhanced" "Detected in many" "BEWO: 258.2;OE19: 299.8;SiHa: 155.1" "Low region specificity" "Detected in all" HPA029561 Approved Approved Nucleoplasm,Mitochondria Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm Mitochondria "HPA029561: AB_10601932" "unprognostic (1.16e-1)" "unprognostic (1.28e-2)" "unprognostic (4.76e-3)" "unprognostic (2.50e-2)" "unprognostic (4.25e-2)" "unprognostic (3.25e-3)" "unprognostic (4.26e-3)" "unprognostic (4.08e-2)" "unprognostic (1.87e-1)" "unprognostic (1.96e-2)" "unprognostic (4.56e-2)" "unprognostic (4.24e-3)" "prognostic favorable (0.00e+0)" "unprognostic (1.95e-1)" "unprognostic (1.19e-1)" "unprognostic (2.08e-2)" "unprognostic (3.35e-2)" 19.8 11.1 2.5 12.3 3.2 31.5 14.8 1.8 4.4 31.0 5.3 50.0 22.4 16.2 1.7 131.2 16.3 19.9 29.5 2.5 2.4 129.4 47.4 23.2 5.7 2.2 2.4 7.8 359.1 5.3 11.1 22.0 2.1 13.7 30.7 0.8 31.0 5.9 257.1 150.0 29.2 15.6 2.3 19.0 53.7 2.9 2.6 5.0 17.4 89.8 7.3 61.0 50.8 2.3 29.3 41.7 11.3 20.4 14.1 10.5 258.2 7.2 18.4 2.9 4.2 35.4 21.7 6.1 17.4 10.1 24.1 19.8 13.2 6.9 0.8 33.5 22.5 0.0 56.0 30.6 8.3 47.5 2.3 23.9 36.3 10.0 5.2 8.5 3.9 30.7 7.4 0.0 10.7 31.8 19.4 27.1 40.5 299.8 42.7 36.0 29.6 28.6 122.1 15.6 15.0 0.3 155.1 35.8 16.2 14.5 33.3 58.5 0.0 5.6 11.5 73.7 7.3 24.5 66.3 17.9 24.0 31.7 9.6 9.4 11.4 26.0 0.7 8.7 0.3 1.5 0.7 0.2 9.0 0.3 0.3 0.5 31.3 0.1 5.8 6.7 1.1 3.1 2.5 3.2 1.8 4.4 2.5 2.4 2.2 2.4 2.1 2.3 2.6 2.3 9.2 19.2 32.7 17.6 7.8 105.5 22.7 32.1 159.4 0.7 16.8 20.2 11.6 72.9 16.1 22.0 0.0 52.5 5.8 72.9 440.3 83.4 2.8 5.7 20.2 6.9 17.5 15.3 4.7 110.6 272.2 16.1 65.2 30.4 2.5 13.4 10.0 66.8 42.5 0.0 1.8 90.2 65.1 37.7 17.0 7.1 4.7 34.2 14.2 5.6 25.5 22.3 2.1 0.5 0.5 56.1 50.1 3.8 8.6 42.9 36.9 498.6 12.3 1.0 105.2 16.0 27.6 0.8 10.1 202.1 141.4 106.3 6.1 14.0 84.4 52.8 INTS14 "C15orf44, DKFZP564O1664, VWA9" ENSG00000138614 "Integrator complex subunit 14" Q96SY0 15 65578753-65611289 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 40.5;Extravillous trophoblasts: 30.5;Syncytiotrophoblasts: 49.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040255, HPA040651" Approved Approved "Nucleoplasm,Nuclear membrane,Nuclear bodies,Mitochondria" No No "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Nuclear bodies, Mitochondria" "Nuclear membrane" "HPA040255: AB_10805710, HPA040651: AB_10796559" "unprognostic (2.92e-1)" "unprognostic (3.01e-1)" "unprognostic (2.78e-1)" "unprognostic (2.41e-1)" "unprognostic (4.06e-1)" "unprognostic (2.35e-2)" "unprognostic (1.36e-1)" "unprognostic (1.63e-1)" "unprognostic (5.80e-2)" "unprognostic (5.60e-2)" "unprognostic (2.57e-2)" "unprognostic (2.67e-2)" "unprognostic (1.03e-3)" "unprognostic (1.92e-2)" "unprognostic (1.23e-1)" "unprognostic (5.75e-2)" "unprognostic (1.30e-1)" 12.5 15.8 13.2 14.2 15.8 18.0 22.3 14.7 16.6 20.9 18.2 21.8 14.1 18.1 27.4 16.1 24.2 19.6 13.4 13.5 14.8 21.3 21.1 15.6 22.7 14.5 14.9 18.4 17.7 22.9 16.3 19.2 14.6 19.1 23.6 13.1 16.2 19.8 9.9 18.0 17.2 18.8 14.8 18.9 18.1 18.9 15.8 25.4 23.2 13.6 24.3 23.6 13.6 17.7 26.4 46.7 46.1 36.8 25.2 31.4 29.5 28.4 36.5 46.4 42.5 42.2 61.2 42.9 38.9 35.6 38.5 52.0 99.4 47.6 40.5 37.8 60.2 37.5 32.2 46.4 50.0 38.7 46.2 30.6 46.9 35.1 53.7 34.1 50.8 64.8 52.2 24.3 33.4 41.7 44.3 41.2 33.8 66.2 25.6 37.5 38.8 49.0 36.7 48.6 33.1 26.3 34.2 34.5 49.5 39.2 32.3 44.0 25.2 31.8 33.2 28.8 45.6 23.9 48.4 58.1 32.1 70.0 38.1 25.7 11.0 6.2 19.8 12.7 22.3 19.3 20.3 22.6 19.8 14.8 21.1 19.2 1.2 23.8 9.5 17.9 30.8 16.6 13.2 15.8 14.7 16.6 13.5 14.8 14.5 14.9 14.6 14.8 15.8 17.7 12.2 22.4 10.9 0.0 3.8 0.0 0.0 0.0 0.0 0.0 13.0 11.0 0.0 0.0 5.6 12.9 0.0 40.5 7.7 0.0 21.5 18.2 0.0 12.8 11.8 6.8 0.0 0.0 0.0 15.4 30.5 6.7 0.0 12.6 7.6 22.5 0.0 0.0 16.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 9.3 0.0 0.0 0.0 0.0 16.6 0.0 0.0 0.5 0.0 0.0 15.1 10.9 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 49.8 4.8 24.0 0.0 0.0 INTS6L "DDX26B, FLJ41215" ENSG00000165359 "Integrator complex subunit 6 like" Q5JSJ4 X 135520659-135582510 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 12.8;Breast myoepithelial cells: 14.0;dendritic cells: 15.9;Endometrial ciliated cells: 16.0;Glandular and luminal cells: 11.1;granulocytes: 25.2;Theca cells: 11.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 20.7;U-937: 19.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001552, HPA013200, HPA013335, HPA030747" Uncertain Approved "Nuclear bodies,Centrosome,Mitochondria" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 24: NB-4 - Immune response" "Cluster 7: Non-specific - Mitochondria" Centrosome "Nuclear bodies, Mitochondria" "HPA001552: AB_1078659, HPA013200: AB_2668801, HPA013335: AB_1847553, HPA030747: AB_2673589" "unprognostic (2.03e-1)" "prognostic favorable (5.39e-4)" "unprognostic (1.96e-1)" "unprognostic (7.42e-2)" "unprognostic (2.89e-2)" "unprognostic (1.43e-3)" "unprognostic (1.43e-1)" "unprognostic (1.27e-1)" "unprognostic (3.75e-2)" "unprognostic (7.33e-3)" "prognostic favorable (5.54e-4)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.28e-8)" "unprognostic (2.87e-1)" "unprognostic (1.81e-1)" "unprognostic (5.37e-2)" "prognostic favorable (2.94e-4)" 3.4 7.5 3.3 6.3 2.9 13.1 3.8 8.7 3.7 6.7 2.6 7.7 2.6 4.6 2.8 4.7 6.5 3.8 4.4 3.0 3.0 3.8 1.1 4.4 12.6 3.5 3.6 8.2 2.1 1.8 6.7 3.3 3.4 5.0 7.1 5.1 12.0 3.6 1.1 6.1 7.3 3.7 3.3 10.2 3.4 6.3 3.4 8.4 3.3 0.8 11.3 5.7 5.1 3.7 0.1 0.0 7.5 8.9 2.2 2.5 0.0 1.9 4.0 2.2 6.6 0.7 3.2 7.5 6.3 1.6 5.4 5.6 8.4 2.5 1.5 5.8 3.0 6.5 0.7 0.0 1.9 6.8 0.5 3.3 2.4 2.5 2.5 3.8 2.8 4.9 4.3 11.8 1.6 5.5 6.5 20.7 3.5 8.0 3.1 5.3 2.4 6.4 1.8 3.0 1.2 2.7 2.6 2.6 0.2 3.2 2.8 12.5 1.6 5.6 3.2 0.0 2.2 13.5 11.2 11.3 1.9 19.0 1.1 0.0 1.6 1.4 2.9 1.4 3.8 3.3 3.4 3.5 2.3 3.5 5.2 3.4 0.8 1.9 1.8 2.2 2.0 2.5 3.3 2.9 8.7 3.7 3.0 3.0 3.5 3.6 3.4 3.3 3.4 3.7 6.8 12.8 5.8 0.0 7.3 0.0 0.0 0.0 0.0 0.0 7.2 14.0 0.0 0.0 3.7 3.7 0.0 2.1 15.9 0.0 0.0 1.3 0.0 16.0 5.3 3.3 0.0 0.0 0.0 1.6 0.3 3.3 0.0 11.1 25.2 7.3 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.2 0.0 0.0 6.3 0.0 0.0 1.0 6.6 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.8 6.9 11.1 0.0 0.0 IRX6 "IRX-3, IRX7" ENSG00000159387 "Iroquois homeobox 6" P78412 16 55324203-55330756 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 9.8;heart muscle: 9.8;skin 1: 8.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 7.5;Collecting duct cells: 5.5;Hofbauer cells: 4.7;Late spermatids: 5.1;Melanocytes: 3.6" "Cancer enhanced" "Detected in many" "melanoma: 5.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.6;HEK 293: 1.9;RPTEC TERT1: 7.1;SK-MEL-30: 4.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA018332 Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 31: Skin - Epidermis development" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Mitochondria" "HPA018332: AB_1851920" "unprognostic (1.22e-1)" "unprognostic (1.02e-1)" "unprognostic (4.93e-4)" "unprognostic (2.48e-2)" "unprognostic (6.50e-2)" "unprognostic (3.46e-1)" "prognostic favorable (3.34e-4)" "unprognostic (3.63e-2)" "unprognostic (4.36e-2)" "unprognostic (2.93e-2)" "unprognostic (1.50e-2)" "unprognostic (2.83e-2)" "unprognostic (9.63e-3)" "unprognostic (7.12e-3)" "unprognostic (5.48e-2)" "unprognostic (5.23e-3)" 9.8 0.1 0.2 0.0 0.6 0.0 4.8 1.1 0.3 2.3 0.0 0.2 0.0 0.2 0.0 0.5 0.1 0.1 9.8 0.0 1.1 2.7 0.0 1.8 0.1 0.5 0.8 0.2 0.1 1.7 0.2 0.1 0.6 0.2 0.0 1.6 1.9 0.0 2.8 8.9 0.3 0.1 0.2 1.3 0.0 0.4 0.6 2.2 0.6 1.3 1.1 0.0 0.5 0.2 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 7.1 0.0 0.1 0.1 0.0 1.1 4.8 0.0 0.3 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 1.1 0.3 0.0 1.1 0.5 0.8 0.6 0.2 0.6 0.2 0.6 0.0 0.0 0.0 0.1 0.8 0.0 0.5 0.0 7.5 0.4 0.6 1.3 0.0 1.2 5.5 0.0 0.0 0.2 0.0 0.0 0.0 1.7 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.8 0.0 0.6 0.0 0.0 4.7 0.0 0.1 0.0 0.0 0.0 0.7 5.1 0.0 0.1 3.6 0.0 0.6 1.5 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.2 0.3 0.1 0.5 0.0 1.0 0.1 0.0 0.0 0.0 0.0 ISL1 "Isl-1, ISLET1" ENSG00000016082 "ISL LIM homeobox 1" P61371 5 51383448-51394730 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 22.9;seminal vesicle: 19.2;vagina: 15.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 207.5;Cytotrophoblasts: 34.4;Enteroendocrine cells: 91.6;Horizontal cells: 43.7;Syncytiotrophoblasts: 34.2" "Group enriched" "Detected in some" 5 "cervical cancer: 1.1;pancreatic cancer: 4.1;prostate cancer: 2.1;stomach cancer: 1.6;testis cancer: 1.4" "Group enriched" "Detected in many" 5 "hypothalamus: 11.5;thalamus: 6.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 16 "SH-SY5Y: 297.1" "Group enriched" "Detected in many" 8 "basal ganglia: 13.8;hypothalamus: 15.0;thalamus: 6.0" "Group enriched" "Detected in some" 9 "basal ganglia: 5.8;hypothalamus: 5.4" "HPA048613, HPA057416" Approved Approved "Nucleoplasm,Nuclear speckles,Mitochondria" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm "Nuclear speckles, Mitochondria" "HPA048613: , HPA057416: AB_2683431" "unprognostic (4.97e-2)" "unprognostic (2.22e-2)" "unprognostic (1.69e-1)" "unprognostic (2.41e-3)" "unprognostic (5.52e-2)" "unprognostic (6.79e-2)" "unprognostic (9.21e-2)" "unprognostic (9.42e-2)" "unprognostic (5.55e-3)" "unprognostic (1.77e-1)" "unprognostic (1.48e-1)" "unprognostic (2.48e-1)" "unprognostic (9.11e-3)" "unprognostic (4.39e-3)" 2.9 1.3 0.4 0.0 1.4 0.0 0.1 0.0 1.8 7.8 0.0 1.1 2.3 0.1 0.1 0.1 0.0 0.0 0.0 0.0 11.5 0.0 0.0 0.0 0.0 1.0 0.5 0.0 4.8 0.0 2.2 7.8 1.2 12.0 2.4 22.9 1.1 19.2 0.0 1.1 0.7 0.1 0.0 0.0 10.0 1.6 6.0 4.3 0.3 0.0 0.4 0.7 15.9 0.2 0.0 0.0 0.0 3.4 0.0 0.0 0.2 3.0 3.8 0.0 0.0 0.3 2.7 0.0 2.5 0.0 0.0 2.2 4.6 3.4 0.0 0.0 7.1 0.0 12.6 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.3 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.9 3.2 0.0 3.0 0.0 0.0 0.0 19.1 297.1 0.0 0.0 0.0 11.6 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.4 0.0 1.8 0.0 11.5 1.0 0.5 1.2 0.0 6.0 0.2 0.0 0.0 0.0 0.0 0.1 1.5 5.1 11.8 0.0 207.5 0.0 0.0 0.2 0.0 2.8 0.0 4.2 34.4 0.0 0.5 0.0 0.1 17.3 0.0 0.0 1.7 91.6 0.0 0.0 0.0 10.9 6.1 11.7 0.0 0.0 0.0 0.0 0.0 2.7 43.7 0.0 1.9 8.2 0.0 0.4 3.2 0.3 0.1 0.0 0.0 0.0 4.1 0.0 0.0 0.0 4.2 0.0 0.0 0.0 1.1 0.0 0.0 0.8 11.8 0.0 0.0 4.0 2.5 7.3 0.0 1.0 34.2 0.0 0.0 0.2 5.6 ISOC2 FLJ23469 ENSG00000063241 "Isochorismatase domain containing 2" Q96AB3 19 55452985-55462343 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 284.3" "Cell type enhanced" "Detected in all" "Hepatocytes: 272.2;Proximal tubular cells: 479.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEK 293: 270.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043142 Enhanced Approved Mitochondria,Cytosol NA NA 220000 "Cluster 27: Non-specific - Gene expression" "Cluster 85: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria Cytosol "HPA043142: AB_10794653" "unprognostic (2.74e-1)" "unprognostic (8.38e-3)" "unprognostic (7.34e-2)" "unprognostic (3.09e-2)" "unprognostic (1.35e-1)" "unprognostic (1.08e-1)" "unprognostic (1.28e-1)" "unprognostic (1.13e-1)" "unprognostic (3.87e-1)" "unprognostic (3.09e-1)" "unprognostic (5.82e-2)" "unprognostic (8.59e-2)" "unprognostic (9.90e-3)" "unprognostic (2.24e-1)" "unprognostic (2.42e-1)" "unprognostic (9.20e-2)" "unprognostic (2.09e-2)" 50.4 55.6 39.7 20.0 41.2 21.4 38.3 42.7 52.4 25.4 48.1 62.1 36.2 28.4 8.1 52.2 25.8 17.2 69.5 39.5 43.9 101.4 284.3 26.4 19.2 46.6 44.4 23.3 44.4 39.9 46.3 9.3 43.7 40.9 16.3 3.3 41.8 28.7 95.7 37.6 37.2 16.8 42.6 50.8 41.4 65.6 42.1 9.9 39.1 49.0 14.0 41.6 30.3 44.4 52.8 78.1 20.1 55.6 13.6 28.4 67.7 37.9 36.7 45.7 46.4 40.0 88.2 98.6 66.2 42.2 44.0 51.1 39.7 46.6 14.6 38.9 270.2 57.6 17.8 128.0 55.6 63.2 163.5 42.5 44.2 29.4 22.0 20.4 42.4 39.3 93.6 61.1 28.9 101.9 0.3 73.6 32.4 113.2 217.9 72.1 44.4 126.0 75.0 47.7 24.7 70.5 35.5 75.3 41.4 11.9 63.8 109.4 32.4 34.0 48.5 38.8 44.7 78.7 73.0 78.7 52.2 79.4 58.3 0.7 16.0 0.9 12.7 33.8 12.6 18.7 11.6 16.2 29.5 12.6 11.5 11.8 0.7 24.3 27.8 24.1 15.2 15.0 39.7 41.2 42.7 52.4 39.5 43.9 46.6 44.4 43.7 42.6 42.1 44.4 25.4 6.4 6.3 5.5 38.0 59.5 65.3 148.8 32.5 12.5 51.7 56.5 20.8 48.6 50.3 62.5 2.1 32.5 19.1 200.1 162.4 65.1 44.5 37.8 39.0 36.9 71.3 46.9 3.5 68.1 105.5 44.2 63.7 25.1 45.2 43.2 28.5 272.2 96.0 13.5 5.4 225.4 87.5 44.5 50.6 43.6 38.8 39.0 62.2 2.8 28.0 53.1 21.6 6.6 12.8 56.4 125.8 30.9 80.5 128.7 253.7 479.9 26.1 10.0 26.3 32.0 39.0 183.8 16.4 69.6 68.6 21.6 19.4 123.4 190.7 74.8 ITPK1 ENSG00000100605 "Inositol-tetrakisphosphate 1-kinase" Q13572 14 92936914-93116320 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Isomerase, Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 106.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 42.9" "Group enriched" "Detected in all" 5 "granulocytes: 42.9;monocytes: 25.9" "Cell line enhanced" "Detected in all" "WM-115: 110.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055230 Approved Approved Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 45: Enterocytes - Digestion" Mitochondria "HPA055230: AB_2682748" "unprognostic (1.93e-3)" "unprognostic (2.50e-1)" "unprognostic (2.15e-1)" "prognostic favorable (8.56e-4)" "unprognostic (4.27e-1)" "unprognostic (2.04e-2)" "unprognostic (6.97e-2)" "unprognostic (1.32e-1)" "unprognostic (1.24e-2)" "unprognostic (2.86e-2)" "unprognostic (8.14e-2)" "unprognostic (2.27e-1)" "unprognostic (1.37e-3)" "unprognostic (2.39e-1)" "unprognostic (2.02e-1)" "unprognostic (4.20e-1)" "unprognostic (7.25e-3)" 60.0 27.2 88.3 15.5 105.9 17.3 45.3 84.7 92.7 57.0 57.2 60.1 44.4 66.8 11.6 24.8 30.3 19.4 59.2 92.5 80.7 35.6 48.3 31.6 9.0 90.2 95.8 27.1 30.7 14.8 20.6 6.8 83.0 38.8 16.4 9.3 21.0 21.7 40.9 22.2 58.5 23.4 83.2 38.1 34.2 29.5 100.4 6.9 25.4 16.1 6.6 62.5 35.0 100.7 28.1 56.6 10.3 26.3 22.5 12.6 27.8 11.8 17.5 22.9 13.8 32.8 48.9 17.7 57.4 18.6 8.7 32.5 29.6 50.3 7.2 65.9 13.1 39.2 14.6 28.5 16.8 17.9 41.5 8.2 29.5 11.6 26.3 9.9 22.8 18.0 21.9 19.8 11.3 74.6 15.5 25.5 22.0 36.4 25.5 29.1 15.1 26.3 15.5 46.3 28.0 35.5 29.6 59.0 49.5 7.8 79.5 21.7 18.0 15.9 17.3 27.0 18.9 19.3 19.1 11.4 14.6 13.8 110.8 5.3 9.8 18.2 3.2 15.4 1.9 3.3 2.0 2.1 7.0 1.0 1.2 2.2 42.9 2.4 25.9 3.5 3.0 5.1 88.3 105.9 84.7 92.7 92.5 80.7 90.2 95.8 83.0 83.2 100.4 100.7 11.8 12.8 11.1 32.0 10.8 7.4 7.5 8.3 2.8 10.2 11.8 7.6 24.3 17.2 5.1 29.5 18.8 9.7 12.9 73.5 13.7 19.2 12.7 18.1 12.5 12.4 28.8 5.9 45.1 27.3 10.0 8.9 13.3 21.2 16.5 9.2 13.9 31.3 19.4 6.7 21.6 24.8 4.1 44.7 11.8 30.3 14.9 30.5 26.6 16.9 23.2 17.2 18.6 31.7 46.5 44.6 38.7 48.2 13.2 15.2 106.6 23.0 3.3 13.7 19.7 7.4 17.8 4.3 14.3 7.0 4.4 6.8 12.7 10.3 34.5 11.0 JADE1 "JADE-1, PHF17" ENSG00000077684 "Jade family PHD finger 1" Q6IE81 4 128809700-128875224 "Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020016 Approved Approved Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 25: Pancreas - Digestion" "Cluster 5: NTERA-2 - Transcription" "Cluster 50: Fibroblasts - ECM organization" Mitochondria "HPA020016: AB_1855292" "unprognostic (1.91e-2)" "unprognostic (1.81e-1)" "unprognostic (4.79e-2)" "unprognostic (1.63e-2)" "unprognostic (3.19e-1)" "unprognostic (2.09e-2)" "unprognostic (7.59e-2)" "unprognostic (6.96e-3)" "unprognostic (6.93e-2)" "unprognostic (8.16e-2)" "unprognostic (9.39e-2)" "unprognostic (8.38e-3)" "prognostic favorable (8.22e-6)" "unprognostic (1.45e-2)" "unprognostic (2.58e-1)" "unprognostic (9.92e-2)" "unprognostic (1.68e-1)" 25.3 21.6 11.7 10.3 12.8 46.2 20.1 21.6 12.4 16.4 10.0 16.3 8.6 12.3 8.7 12.2 18.5 12.6 17.7 10.2 15.9 24.7 11.7 15.9 15.2 13.6 14.1 27.9 70.8 16.5 15.0 11.2 14.8 18.0 6.2 20.4 18.9 17.2 14.9 13.4 12.3 12.7 12.0 15.4 19.1 9.7 15.8 17.8 31.4 11.5 12.3 19.5 12.9 12.1 13.5 25.8 25.2 18.6 33.7 23.7 32.9 21.0 12.5 22.4 20.4 22.8 22.9 40.8 24.3 12.1 9.8 4.5 29.8 7.4 24.9 31.9 13.5 22.8 35.9 20.9 57.9 37.5 17.6 26.5 11.5 27.3 20.2 18.5 24.5 26.1 36.7 54.3 17.5 16.2 47.8 28.0 67.8 13.5 13.1 35.0 17.3 22.0 35.7 6.5 32.7 23.7 20.1 16.2 16.5 35.0 13.1 20.9 17.1 21.9 36.3 16.9 24.8 35.9 32.0 46.0 23.7 36.8 18.3 31.4 10.7 35.9 17.2 17.2 21.1 13.4 18.3 19.2 10.4 18.6 25.5 19.9 13.8 31.1 23.6 4.9 14.6 16.3 11.7 12.8 21.6 12.4 10.2 15.9 13.6 14.1 14.8 12.0 15.8 12.1 24.5 38.5 25.4 17.6 35.4 14.9 16.1 4.3 32.5 40.3 25.8 32.3 33.9 42.9 13.7 49.7 50.1 25.2 42.0 3.1 19.6 30.1 3.6 45.5 21.7 21.7 10.2 48.8 24.5 48.7 16.5 36.7 25.5 37.0 17.7 34.3 18.2 37.3 10.1 28.6 31.8 8.3 46.8 28.5 14.3 4.2 36.1 16.3 21.4 12.2 27.5 26.7 107.1 17.1 19.2 44.0 7.8 48.2 41.2 12.6 12.6 34.7 29.7 28.4 85.5 33.0 59.0 6.6 21.9 20.9 13.4 4.0 40.9 8.9 10.8 5.9 JARID2 JMJ ENSG00000008083 "Jumonji and AT-rich interaction domain containing 2" Q92833 6 15246069-15522042 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Chromatin regulator, Developmental protein, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 57.8" "Cell type enhanced" "Detected in all" "Langerhans cells: 195.0" "Cancer enhanced" "Detected in all" "testis cancer: 34.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "JURKAT: 73.8;SuSa: 78.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063889, CAB069890" Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Mitochondria" "CAB069890: AB_10000529, HPA063889: AB_2685143" "unprognostic (5.06e-2)" "unprognostic (1.82e-1)" "unprognostic (1.08e-1)" "unprognostic (1.05e-2)" "unprognostic (1.18e-1)" "unprognostic (1.43e-1)" "unprognostic (4.87e-3)" "unprognostic (6.35e-2)" "unprognostic (2.57e-2)" "unprognostic (1.30e-2)" "unprognostic (2.18e-1)" "unprognostic (3.60e-2)" "unprognostic (3.26e-3)" "unprognostic (7.04e-2)" "unprognostic (4.48e-2)" "unprognostic (2.78e-2)" "unprognostic (1.99e-1)" 7.3 4.7 6.7 9.2 7.1 57.8 6.0 23.6 8.7 5.3 3.7 5.0 5.7 5.0 6.7 13.7 3.9 4.4 6.4 7.5 6.2 4.1 3.6 7.2 9.0 7.1 6.8 5.7 3.5 3.6 4.4 7.1 7.8 4.5 4.6 20.0 6.4 3.3 11.8 13.4 6.8 4.1 5.2 10.6 7.0 16.0 8.0 20.0 3.8 4.3 9.8 5.8 6.8 8.2 12.4 8.5 34.0 19.6 4.1 4.0 33.5 3.5 8.3 4.5 5.5 8.8 9.4 6.5 12.3 7.1 6.8 6.3 8.0 20.1 4.1 13.0 12.4 23.3 10.6 11.6 4.6 23.9 26.3 5.7 12.3 6.6 26.2 13.4 4.7 73.8 30.5 10.8 2.7 12.6 47.6 44.6 36.4 6.1 3.8 20.9 10.4 18.6 4.2 13.0 26.2 15.0 7.3 24.9 32.1 78.1 8.7 25.0 8.5 20.6 11.4 11.5 12.3 6.9 17.8 11.7 7.0 21.9 26.6 10.1 3.8 3.2 3.4 2.4 2.9 2.5 1.6 2.1 3.1 3.4 2.1 2.9 13.2 4.9 2.7 4.4 1.4 2.1 6.7 7.1 23.6 8.7 7.5 6.2 7.1 6.8 7.8 5.2 8.0 8.2 30.1 6.4 12.8 175.3 40.7 80.4 10.7 23.0 31.9 74.2 28.3 23.1 10.5 15.7 17.1 5.5 87.6 27.0 62.9 10.0 1.9 8.2 89.2 30.7 18.0 27.1 26.8 50.9 125.9 4.4 25.0 17.6 19.9 77.5 25.3 14.8 15.7 13.8 24.0 154.8 124.4 16.4 16.2 61.3 195.0 40.8 8.7 89.5 26.6 97.4 49.1 134.0 54.6 136.7 136.6 15.6 9.3 8.6 34.9 6.8 16.6 3.8 8.7 89.7 6.6 18.1 23.6 9.4 71.1 43.4 151.6 25.2 43.2 17.4 14.7 15.4 KCNAB3 "AKR6A9, KCNA3B" ENSG00000170049 "Potassium voltage-gated channel subfamily A regulatory beta subunit 3" O43448 17 7921859-7929803 "Predicted intracellular proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 14.3;retina: 12.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 29.3;Horizontal cells: 131.2;Inhibitory neurons: 40.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "REH: 13.2;SH-SY5Y: 6.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077993 Approved Mitochondria NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 14: REH - Unknown function" "Cluster 62: Horizontal cells - Visual perception" Mitochondria "HPA077993: AB_2686872" "unprognostic (3.02e-2)" "unprognostic (5.59e-2)" "unprognostic (6.95e-2)" "unprognostic (2.62e-2)" "unprognostic (6.13e-2)" "unprognostic (5.84e-4)" "unprognostic (2.19e-1)" "unprognostic (5.72e-2)" "unprognostic (8.50e-2)" "unprognostic (8.55e-2)" "unprognostic (3.27e-4)" "unprognostic (7.47e-3)" "unprognostic (3.03e-6)" "unprognostic (2.12e-1)" "unprognostic (5.00e-2)" "unprognostic (4.97e-2)" "unprognostic (9.54e-3)" 2.0 0.6 3.4 1.4 3.9 3.2 1.3 9.8 7.6 4.6 1.8 1.6 0.5 14.3 0.9 1.0 4.7 0.9 0.6 3.3 2.7 3.1 1.5 1.5 2.0 3.2 8.3 2.8 1.4 0.1 4.1 0.7 3.9 3.1 0.9 12.8 1.2 0.5 0.4 1.7 2.2 5.6 3.0 3.1 1.3 2.0 5.1 1.4 2.2 0.0 1.6 0.9 1.3 4.4 1.2 1.0 4.7 1.2 0.5 1.2 1.7 4.2 2.7 3.6 4.0 0.6 0.3 2.0 0.2 0.7 0.1 0.4 1.3 0.6 5.0 1.6 1.9 0.6 1.0 0.0 4.2 0.2 2.5 1.8 1.3 3.8 0.2 0.2 0.3 5.3 0.4 0.3 0.6 0.9 0.7 2.3 0.7 0.0 0.6 13.2 1.3 0.5 0.4 1.5 0.2 6.8 0.4 0.0 0.9 0.2 1.2 0.1 0.3 0.6 2.3 0.9 0.3 1.0 1.1 1.1 1.8 2.6 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 3.4 3.9 9.8 7.6 3.3 2.7 3.2 8.3 3.9 3.0 5.1 4.4 1.6 3.2 2.7 2.6 1.0 0.5 0.6 0.4 0.6 29.3 0.6 1.4 0.8 0.0 0.7 0.0 4.2 0.3 2.2 0.8 0.0 0.8 0.6 0.9 15.7 0.8 0.0 0.0 6.8 0.5 0.3 2.2 0.5 1.3 1.3 3.6 0.4 0.3 0.7 131.2 40.3 0.4 0.0 0.6 0.7 0.7 1.8 1.1 0.0 0.0 1.5 11.3 2.1 10.6 2.1 0.7 0.1 0.7 0.9 0.6 0.3 0.2 0.1 7.6 0.0 0.5 1.1 8.3 2.6 0.1 0.4 0.1 1.3 3.0 0.6 0.2 KCNH3 "BEC1, elk2, Kv12.2" ENSG00000135519 "Potassium voltage-gated channel subfamily H member 3" Q9ULD8 12 49539030-49558337 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 39.4;pituitary gland: 25.7" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 11.4;Excitatory neurons: 58.2;Inhibitory neurons: 19.2;Late spermatids: 10.6;Respiratory ciliated cells: 10.9" "Cancer enhanced" "Detected in many" "endometrial cancer: 9.8" "Group enriched" "Detected in many" 21 "amygdala: 29.6;basal ganglia: 25.6;cerebral cortex: 39.4;hippocampal formation: 30.6;white matter: 24.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 5.8;AN3-CA: 3.5;HMC-1: 3.4;RPTEC TERT1: 9.1;U-2 OS: 8.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA051088 Approved Nucleoplasm,Mitochondria NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Mitochondria" "HPA051088: AB_2681340" "unprognostic (5.69e-3)" "unprognostic (1.36e-1)" "unprognostic (8.87e-4)" "unprognostic (8.24e-3)" "unprognostic (7.54e-2)" "unprognostic (2.38e-2)" "unprognostic (3.63e-2)" "unprognostic (2.66e-1)" "unprognostic (9.91e-3)" "unprognostic (5.28e-2)" "unprognostic (6.39e-5)" "unprognostic (1.68e-1)" "unprognostic (1.07e-4)" "unprognostic (5.52e-3)" "unprognostic (2.67e-1)" "unprognostic (1.27e-1)" "unprognostic (2.86e-1)" 0.3 2.9 29.6 0.0 25.6 0.2 0.6 0.0 39.4 0.8 0.0 0.2 0.1 0.6 0.1 0.1 5.8 0.3 0.8 30.6 1.3 3.4 0.3 1.0 0.5 0.0 0.2 0.3 1.3 2.6 25.7 0.0 0.6 0.7 0.0 0.0 0.3 0.3 0.1 0.3 0.3 0.0 0.0 1.4 0.3 2.8 1.4 0.2 1.3 0.0 0.2 0.1 0.3 24.8 0.4 5.8 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.4 0.0 0.2 1.7 0.6 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 1.5 0.0 0.2 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 9.1 0.0 0.9 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 8.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.4 0.0 0.1 0.0 0.0 0.0 0.0 29.6 25.6 0.0 39.4 30.6 1.3 0.0 0.2 0.6 0.0 1.4 24.8 0.1 0.0 0.5 4.9 0.0 0.1 0.2 0.5 0.0 0.1 0.1 2.0 1.0 5.7 0.2 0.0 0.0 0.0 0.4 0.1 0.0 0.2 6.0 11.4 0.4 0.1 2.4 0.0 58.2 0.0 0.1 0.6 0.0 0.5 0.0 2.4 0.7 0.0 0.0 1.7 19.2 0.0 0.0 0.6 0.5 10.6 0.3 0.6 0.0 1.0 0.7 0.4 2.1 6.0 2.6 0.1 0.1 1.2 0.1 0.0 0.0 0.2 10.9 0.3 0.0 0.4 0.3 1.1 3.4 0.0 0.3 0.0 0.7 0.0 0.2 0.0 KCNJ3 "GIRK1, KGA, Kir3.1" ENSG00000162989 "Potassium inwardly rectifying channel subfamily J member 3" P48549 2 154697855-154858354 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.7" "Group enriched" "Detected in many" 5 "Excitatory neurons: 309.6;Horizontal cells: 124.5;Inhibitory neurons: 431.3" "Group enriched" "Detected in many" 5 "breast cancer: 12.2;renal cancer: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 1.5;SH-SY5Y: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024231, HPA064138" Uncertain Approved "Plasma membrane,Mitochondria" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "Plasma membrane" "HPA024231: AB_1855558, HPA064138: " "unprognostic (1.45e-1)" "unprognostic (9.42e-2)" "unprognostic (2.66e-2)" "unprognostic (4.49e-4)" "unprognostic (8.89e-2)" "unprognostic (6.81e-2)" "unprognostic (7.24e-3)" "unprognostic (1.15e-2)" "unprognostic (4.25e-3)" "unprognostic (3.72e-3)" "unprognostic (3.33e-1)" "unprognostic (8.90e-3)" "unprognostic (3.75e-2)" "unprognostic (5.59e-1)" "unprognostic (2.32e-1)" "unprognostic (1.17e-1)" 0.5 1.4 5.7 0.1 8.7 0.1 0.3 32.7 17.0 1.6 4.7 0.8 10.7 0.1 1.1 0.1 0.4 1.3 15.1 14.6 3.7 10.5 3.1 0.2 0.0 2.2 4.3 0.1 2.1 10.4 6.8 0.0 2.4 6.5 0.8 5.0 0.0 11.3 5.3 0.1 9.5 0.2 1.6 0.4 0.7 0.4 4.1 0.0 0.1 0.2 0.0 0.4 0.6 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.4 1.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.9 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.3 0.3 0.2 0.1 0.1 0.1 5.7 8.7 32.7 17.0 14.6 3.7 2.2 4.3 2.4 1.6 4.1 6.4 0.3 0.0 0.0 38.8 0.0 0.8 5.3 0.0 0.0 10.9 3.7 1.7 49.0 5.7 0.0 20.2 14.6 0.0 0.0 0.1 5.9 0.1 0.3 0.0 0.0 1.3 31.1 0.0 309.6 3.2 0.0 5.4 0.0 0.0 0.0 0.0 0.0 1.3 0.1 124.5 431.3 7.0 0.0 0.0 2.1 0.0 6.2 0.6 1.8 5.6 0.0 0.7 0.0 32.6 6.8 0.0 1.2 4.1 0.0 6.1 16.2 8.7 0.0 3.9 0.0 8.0 1.6 0.4 0.3 0.0 1.8 0.0 0.8 1.9 8.4 4.7 KCNMB3 "KCNMB2, KCNMBL" ENSG00000171121 "Potassium calcium-activated channel subfamily M regulatory beta subunit 3" Q9NPA1 3 179236691-179267002 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 14.6;Early spermatids: 11.2;Late spermatids: 13.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 4.8;HEL: 8.1;NB-4: 5.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA015665, HPA019185" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 32: U-937 - Innate immune response" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm Mitochondria "HPA015665: AB_1852142, HPA019185: AB_1852144" "unprognostic (2.50e-1)" "unprognostic (1.32e-1)" "unprognostic (6.76e-5)" "unprognostic (2.65e-2)" "unprognostic (2.22e-2)" "unprognostic (2.08e-1)" "unprognostic (4.59e-3)" "unprognostic (1.14e-1)" "unprognostic (9.15e-3)" "unprognostic (5.09e-2)" "unprognostic (1.87e-2)" "unprognostic (1.95e-5)" "unprognostic (5.93e-10)" "unprognostic (7.22e-2)" "unprognostic (4.72e-1)" "unprognostic (8.69e-2)" "unprognostic (3.49e-2)" 4.9 3.6 1.5 2.2 1.8 1.1 4.6 1.7 1.9 3.5 1.6 4.0 1.5 3.2 1.5 2.0 2.9 1.7 3.5 1.5 1.7 4.8 5.5 3.0 2.2 1.9 1.7 3.2 5.3 1.2 3.3 4.2 1.8 4.2 1.5 2.3 3.1 1.1 1.3 2.4 3.5 1.4 1.3 7.5 3.7 3.9 1.7 0.9 3.2 0.5 1.9 3.7 2.7 1.7 2.2 0.5 0.8 0.0 0.9 0.8 1.3 0.6 0.3 0.9 0.4 4.8 1.9 0.1 2.1 0.4 1.8 0.8 0.0 0.1 1.0 2.7 0.3 8.1 2.6 1.8 0.8 0.1 2.5 1.3 0.4 0.6 0.0 0.7 0.8 0.0 0.3 0.0 1.1 1.5 0.1 5.7 0.0 0.9 1.6 2.4 0.0 0.1 0.7 1.5 1.1 0.2 0.7 0.8 0.5 0.7 2.1 4.4 0.5 0.4 0.7 0.2 0.6 0.7 0.3 2.6 0.4 3.1 0.6 0.8 0.1 0.1 0.3 0.1 0.2 1.2 0.2 0.3 0.0 0.6 0.2 0.2 0.6 1.1 0.0 0.1 0.4 0.0 1.5 1.8 1.7 1.9 1.5 1.7 1.9 1.7 1.8 1.3 1.7 1.7 4.2 0.0 3.6 3.9 2.9 0.3 1.4 0.3 0.0 2.5 2.1 1.3 1.1 2.8 1.5 0.0 14.6 1.2 0.6 3.8 0.0 5.0 11.2 1.5 2.3 5.3 4.9 0.8 3.4 3.6 1.3 1.5 0.5 2.0 2.5 3.4 2.9 1.4 1.1 0.0 4.6 1.4 0.0 2.1 1.9 13.3 2.8 1.4 0.0 5.6 1.4 1.8 1.0 4.0 6.4 3.3 0.8 3.0 0.9 1.7 1.9 0.3 1.1 7.8 6.6 1.6 1.6 2.0 2.6 0.3 0.1 1.2 1.0 2.3 1.4 1.0 KCTD12 "C13orf2, KIAA1778, PFET1" ENSG00000178695 "Potassium channel tetramerization domain containing 12" Q96CX2 13 76880175-76886405 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 281.2;Endothelial cells: 192.2;Enteroendocrine cells: 386.7;Hofbauer cells: 218.9;Kupffer cells: 395.9;Macrophages: 221.3;monocytes: 206.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 3.9;myeloid DC: 3.7" "Group enriched" "Detected in many" 17 "dendritic cells: 3.7;granulocytes: 1.0;monocytes: 3.9" "Cell line enhanced" "Detected in many" "ASC diff: 111.4;HUVEC TERT2: 229.0;TIME: 186.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056987, HPA077376" Supported Approved Mitochondria NA NA 21000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" Mitochondria "HPA056987: , HPA077376: " "unprognostic (6.42e-2)" "unprognostic (2.67e-1)" "unprognostic (5.13e-1)" "unprognostic (1.04e-3)" "unprognostic (5.82e-2)" "unprognostic (3.98e-2)" "unprognostic (2.02e-1)" "unprognostic (1.32e-3)" "unprognostic (1.35e-2)" "unprognostic (1.90e-1)" "unprognostic (9.83e-3)" "unprognostic (1.23e-1)" "prognostic favorable (1.14e-4)" "unprognostic (2.11e-2)" "unprognostic (1.65e-2)" "unprognostic (1.07e-1)" "unprognostic (9.25e-2)" 76.1 27.8 21.4 55.7 20.1 12.0 52.4 27.0 20.8 44.5 12.4 39.5 22.5 51.3 17.8 38.3 75.0 55.0 22.6 26.9 27.8 31.0 13.9 58.0 39.4 36.2 33.5 47.1 12.5 25.2 6.4 83.9 31.4 14.7 42.5 3.4 20.0 18.5 16.6 22.9 28.1 65.3 37.0 64.8 28.0 26.9 31.4 18.3 16.4 37.1 33.4 39.2 17.4 34.4 1.7 1.5 15.3 0.0 111.4 52.5 4.3 6.9 1.5 4.2 5.5 0.5 0.3 0.0 3.8 18.8 4.9 53.9 6.6 66.4 3.5 1.5 35.1 0.2 38.3 0.0 4.7 18.6 0.1 21.4 21.5 2.7 48.9 8.5 229.0 13.2 0.3 0.2 53.9 1.4 8.5 0.3 7.8 16.6 7.7 0.4 7.4 19.6 17.7 0.2 4.3 7.9 17.3 0.5 2.2 18.5 1.0 12.1 186.0 2.7 4.9 0.4 14.0 2.7 0.5 0.0 42.5 4.0 16.1 0.0 3.9 0.7 0.0 2.5 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.1 1.0 0.0 1.5 1.9 0.0 0.9 21.4 20.1 27.0 20.8 26.9 27.8 36.2 33.5 31.4 37.0 31.4 34.4 281.2 25.6 8.4 2.9 7.5 40.0 2.7 11.9 28.5 4.4 11.2 27.3 21.8 4.3 16.3 97.5 14.6 3.0 30.4 19.7 17.6 6.5 3.6 4.9 44.6 192.2 386.7 6.1 4.8 0.6 90.6 80.0 12.2 3.3 7.0 53.1 61.1 2.5 218.9 0.0 11.5 71.5 12.2 395.9 75.4 11.8 157.2 221.3 51.6 45.9 206.7 4.8 7.2 0.5 0.9 0.5 15.7 44.8 7.6 4.5 0.7 7.5 72.8 1.5 26.3 153.2 32.2 1.9 7.0 16.9 34.4 4.2 5.5 24.0 46.6 1.9 KCTD18 "6530404F10Rik, FLJ31322, FLJ37818" ENSG00000155729 "Potassium channel tetramerization domain containing 18" Q6PI47 2 200488958-200519784 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045498, HPA058028" Approved Approved Mitochondria NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 51: Myeloid cells - Hemostasis" Mitochondria "HPA045498: AB_10959387, HPA058028: AB_2683583" "unprognostic (2.90e-1)" "unprognostic (1.81e-1)" "unprognostic (1.57e-1)" "unprognostic (2.55e-1)" "unprognostic (4.01e-1)" "unprognostic (3.64e-2)" "unprognostic (1.02e-1)" "unprognostic (2.16e-1)" "unprognostic (2.76e-2)" "unprognostic (2.40e-2)" "unprognostic (1.18e-2)" "unprognostic (5.21e-1)" "unprognostic (1.81e-1)" "unprognostic (2.04e-1)" "unprognostic (6.58e-2)" "unprognostic (1.05e-2)" "unprognostic (1.31e-1)" 9.9 8.9 8.2 7.6 9.6 9.8 10.2 8.9 9.9 8.4 9.0 10.1 8.7 8.5 8.2 9.0 8.8 7.2 8.4 7.8 8.5 9.9 10.0 8.5 11.0 9.1 9.1 10.4 11.9 10.4 6.3 6.2 9.3 11.1 8.4 5.6 10.6 9.4 10.6 9.2 7.9 7.7 9.0 10.2 9.3 7.2 8.7 10.6 13.8 8.9 11.0 9.8 8.0 9.4 10.2 9.3 4.5 16.9 21.2 26.2 11.6 12.3 15.4 7.7 10.1 7.5 11.4 7.1 9.1 12.4 12.6 9.6 4.5 14.8 9.8 17.3 4.9 10.2 6.7 5.3 14.4 8.4 11.6 17.6 27.4 8.9 16.9 17.9 6.7 10.5 7.1 9.5 13.9 10.5 18.2 8.2 2.5 8.7 8.3 12.5 10.2 8.4 10.1 10.0 5.1 7.1 9.7 8.2 15.1 9.7 10.9 13.4 11.4 15.7 3.6 8.0 5.9 18.1 14.0 8.0 18.0 8.8 11.3 7.8 3.2 6.4 3.2 4.7 4.9 4.0 4.1 4.8 3.4 4.0 5.1 5.1 2.5 4.6 3.2 4.1 5.0 3.2 8.2 9.6 8.9 9.9 7.8 8.5 9.1 9.1 9.3 9.0 8.7 9.4 7.8 6.4 9.4 7.2 11.3 4.5 5.9 5.7 10.8 7.2 9.1 6.9 6.2 8.6 6.5 3.7 0.0 8.0 10.8 5.6 1.9 7.2 22.7 8.8 7.3 5.7 1.2 3.4 10.1 8.4 7.8 8.6 8.2 5.3 2.5 11.8 8.6 9.4 7.2 10.1 9.5 8.4 6.1 11.4 6.6 4.2 11.8 11.2 7.2 6.5 16.7 11.1 18.6 6.6 18.3 6.5 7.4 12.4 7.5 5.8 8.5 13.5 9.8 10.5 19.7 12.2 7.9 19.0 16.5 12.8 4.0 5.1 10.1 11.0 7.3 4.0 KCTD6 "KCASH3, MGC27385" ENSG00000168301 "Potassium channel tetramerization domain containing 6" Q8NC69 3 58492096-58502360 "Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 52.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "T-47d: 62.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036100, HPA036101" Uncertain Approved Nucleoli,Mitochondria NA NA "Cluster 38: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 6: T47d - Mammary gland" "Cluster 40: Granulosa cells - Unknown function" "Nucleoli, Mitochondria" "HPA036100: AB_10673230, HPA036101: AB_2674941" "unprognostic (8.63e-3)" "unprognostic (1.28e-2)" "unprognostic (3.37e-2)" "unprognostic (5.71e-2)" "unprognostic (9.00e-3)" "unprognostic (2.45e-2)" "prognostic unfavorable (4.57e-4)" "unprognostic (3.19e-2)" "unprognostic (1.81e-1)" "unprognostic (4.67e-3)" "unprognostic (9.36e-3)" "unprognostic (7.48e-2)" "prognostic favorable (8.63e-4)" "unprognostic (1.56e-2)" "unprognostic (1.71e-1)" "unprognostic (3.48e-1)" "unprognostic (2.44e-2)" 9.7 9.3 32.4 5.2 34.1 17.1 12.8 41.4 40.7 13.6 35.5 12.5 6.6 13.8 30.9 14.1 13.7 9.9 10.2 37.5 30.2 20.9 17.1 7.7 8.6 32.7 33.9 14.7 8.2 11.2 20.5 12.8 32.2 11.1 9.0 45.8 7.7 10.2 8.7 8.6 8.0 12.6 31.4 11.1 8.3 6.8 31.1 8.5 14.0 12.5 8.8 9.7 14.5 43.0 10.2 9.5 27.8 12.0 23.9 16.9 10.4 12.0 10.7 17.4 20.3 9.2 5.5 20.0 3.9 8.6 20.3 5.4 22.8 7.0 15.4 20.7 10.4 9.3 24.4 11.2 11.3 7.1 7.2 10.4 10.8 13.8 8.7 41.0 11.6 6.9 5.2 9.2 15.2 9.6 11.0 11.3 20.4 9.1 17.8 10.9 7.7 14.3 16.7 4.7 15.5 13.6 6.6 15.5 8.7 21.2 62.9 5.3 6.3 15.6 14.4 20.1 18.4 10.1 16.9 23.6 13.7 14.8 12.2 27.2 16.3 11.4 14.5 17.0 16.9 14.3 10.6 13.8 23.1 11.3 11.9 10.1 5.3 9.6 12.5 8.9 11.4 8.2 32.4 34.1 41.4 40.7 37.5 30.2 32.7 33.9 32.2 31.4 31.1 43.0 5.7 3.2 2.7 30.3 6.9 8.9 10.5 4.1 8.6 20.8 6.7 4.6 8.8 10.0 8.0 9.2 25.0 10.1 10.7 4.2 19.6 8.5 5.0 3.8 6.8 8.7 9.1 8.6 14.8 4.0 6.8 11.9 2.0 3.9 0.0 52.2 8.9 6.9 6.7 25.2 19.7 4.4 10.2 9.1 14.3 2.2 10.8 6.5 12.4 5.6 11.7 23.2 10.3 14.1 19.6 3.7 5.8 12.0 3.7 9.3 4.5 28.4 3.7 19.2 0.0 9.3 8.2 13.8 22.9 11.5 10.1 8.8 5.0 12.9 6.4 4.0 KHDC1 "bA257K9.4, C6orf147, C6orf148, Em:AC019205.8, MGC10818, NDG1" ENSG00000135314 "KH domain containing 1" Q4VXA5 6 73241314-73310365 "Predicted intracellular proteins, Predicted membrane proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 32.9;Inhibitory neurons: 30.7;Oligodendrocyte precursor cells: 29.1;Spermatocytes: 38.8;Spermatogonia: 20.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" HPA029032 Approved Mitochondria,Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Mitochondria, Cytosol" "HPA029032: AB_10602914" "unprognostic (3.46e-1)" "unprognostic (2.20e-2)" "unprognostic (1.74e-1)" "unprognostic (2.73e-4)" "unprognostic (1.95e-1)" "unprognostic (2.18e-1)" "unprognostic (1.20e-1)" "unprognostic (7.54e-2)" "unprognostic (5.76e-2)" "unprognostic (6.27e-2)" "unprognostic (1.16e-1)" "unprognostic (4.97e-3)" "unprognostic (1.83e-4)" "unprognostic (8.18e-2)" "unprognostic (2.97e-1)" "unprognostic (2.14e-1)" "unprognostic (5.17e-3)" 1.2 1.0 11.0 0.6 11.6 0.2 0.9 11.4 13.6 2.1 8.8 1.6 0.1 1.7 1.2 1.0 2.5 1.0 3.9 11.2 11.2 1.0 0.1 0.8 1.3 10.8 11.2 3.0 2.7 2.2 7.5 0.5 11.3 2.0 0.4 3.8 0.6 1.3 1.1 0.4 0.8 0.9 11.3 0.7 1.6 8.3 11.6 2.1 2.4 1.4 1.4 1.4 1.6 11.4 3.2 4.6 0.9 2.4 4.2 4.8 2.2 6.1 6.0 9.3 13.7 4.4 2.5 6.9 2.3 2.7 4.8 3.1 6.4 1.3 7.1 6.5 4.6 4.6 4.2 0.0 5.4 2.3 0.1 6.2 2.7 9.3 2.6 3.9 2.1 7.1 3.4 8.0 3.8 7.7 0.5 2.1 4.2 0.6 9.1 1.0 0.0 5.5 1.5 0.1 11.1 2.4 3.6 0.2 0.3 3.0 0.1 6.8 0.1 2.0 4.2 1.2 6.6 13.5 8.8 4.9 0.1 1.9 0.7 1.9 0.1 0.0 2.1 0.0 1.3 1.2 1.3 2.4 0.4 0.8 1.0 1.6 0.0 1.4 0.0 1.3 2.8 1.1 11.0 11.6 11.4 13.6 11.2 11.2 10.8 11.2 11.3 11.3 11.6 11.4 0.3 0.0 1.5 8.5 2.8 0.8 3.4 5.4 2.8 9.6 2.0 6.5 2.8 0.0 2.1 3.7 2.1 1.7 4.7 0.3 1.9 0.9 12.0 4.6 2.8 0.4 0.0 1.3 32.9 3.7 0.4 3.6 8.2 0.8 0.0 5.8 0.0 0.0 0.5 13.5 30.7 0.7 2.0 0.0 0.4 15.2 2.1 0.3 3.6 2.8 0.7 16.1 3.1 29.1 11.2 3.2 0.2 3.4 6.8 2.0 0.1 0.2 1.4 7.2 19.7 1.9 2.0 38.8 20.9 1.0 0.6 0.1 2.5 2.7 1.1 0.8 KIAA0930 "bK268H5.C22.1, C22orf9" ENSG00000100364 KIAA0930 Q6ICG6 22 45192244-45240894 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 211.9" "Cell type enhanced" "Detected in many" "Astrocytes: 132.2;Excitatory neurons: 139.6;Oligodendrocytes: 152.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 11.0;eosinophil: 8.6;intermediate monocyte: 13.9;myeloid DC: 12.1;non-classical monocyte: 17.3;plasmacytoid DC: 10.0" "Group enriched" "Detected in all" 5 "dendritic cells: 12.1;granulocytes: 8.6;monocytes: 17.3" "Cell line enhanced" "Detected in many" "THP-1: 327.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038091 Uncertain Approved "Nucleoplasm,Nuclear membrane,Mitochondria" No No "Cluster 51: Monocytes - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear membrane, Mitochondria" Nucleoplasm "HPA038091: AB_10675627" "unprognostic (4.16e-2)" "unprognostic (1.27e-2)" "unprognostic (1.99e-1)" "prognostic favorable (9.22e-5)" "unprognostic (3.16e-2)" "unprognostic (2.44e-1)" "prognostic unfavorable (6.90e-8)" "unprognostic (2.80e-1)" "unprognostic (2.03e-1)" "unprognostic (3.58e-2)" "unprognostic (2.23e-1)" "unprognostic (4.44e-1)" "prognostic unfavorable (8.95e-7)" "unprognostic (6.89e-3)" "unprognostic (5.32e-2)" "unprognostic (5.58e-2)" "unprognostic (1.15e-1)" 33.9 58.3 195.7 27.7 209.3 24.7 25.9 163.3 211.9 46.0 130.3 29.4 14.6 24.0 40.4 34.5 18.2 16.0 18.1 184.1 189.1 23.8 48.4 24.8 29.0 182.8 192.6 13.6 20.1 18.5 19.2 12.0 179.8 29.1 11.2 3.5 26.7 24.7 33.8 64.0 21.4 15.2 170.4 38.7 18.6 26.2 193.6 20.4 18.4 13.1 22.3 44.0 35.6 210.3 49.6 31.5 19.1 38.3 64.1 30.2 19.2 26.9 26.8 28.2 24.1 29.5 26.5 33.2 39.2 42.8 22.5 54.5 29.5 118.6 10.7 35.6 46.4 0.1 42.0 34.3 25.7 89.4 19.7 17.1 59.2 27.3 45.3 21.5 26.8 23.9 11.7 53.1 17.4 56.9 40.0 82.8 18.9 35.8 26.5 48.1 12.9 110.7 42.6 29.7 15.9 28.4 42.5 57.6 75.5 36.8 28.1 327.8 36.5 29.0 50.6 39.7 15.7 44.9 32.9 32.1 34.0 133.7 30.3 0.8 11.0 8.6 2.3 13.9 1.6 2.3 0.9 2.6 12.1 1.8 0.9 1.6 2.5 1.9 17.3 10.0 2.0 3.7 195.7 209.3 163.3 211.9 184.1 189.1 182.8 192.6 179.8 170.4 193.6 210.3 11.4 6.4 8.8 132.2 9.9 52.8 18.6 22.7 6.8 7.3 13.9 13.5 11.5 12.8 11.8 18.4 6.2 2.0 24.9 16.2 0.0 18.6 2.9 11.6 9.3 9.7 10.7 23.1 139.6 20.7 6.5 32.7 4.6 19.5 2.5 3.8 17.5 23.3 67.5 5.0 56.7 10.0 14.2 71.1 50.0 10.8 10.8 59.8 44.4 24.4 68.5 6.5 13.4 16.1 152.9 18.0 13.7 14.7 11.2 25.6 15.7 13.8 9.3 5.9 0.0 10.2 10.9 7.5 4.4 15.2 57.3 2.7 9.3 5.3 12.8 23.1 KLC2 FLJ12387 ENSG00000174996 "Kinesin light chain 2" Q9H0B6 11 66257294-66267860 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Motor protein" "Hereditary spastic paraplegia, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Horizontal cells: 55.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040416, HPA040434" Approved Supported "Nucleoplasm,Plasma membrane,Mitochondria,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane, Cytosol" "Nucleoplasm, Mitochondria" "HPA040416: AB_10795524, HPA040434: AB_10795367" "unprognostic (1.29e-1)" "unprognostic (4.95e-3)" "unprognostic (2.99e-1)" "unprognostic (3.24e-2)" "unprognostic (2.33e-1)" "prognostic unfavorable (3.16e-4)" "unprognostic (2.43e-3)" "unprognostic (2.45e-2)" "unprognostic (6.27e-3)" "unprognostic (1.60e-1)" "unprognostic (3.49e-2)" "unprognostic (1.64e-3)" "unprognostic (4.57e-3)" "unprognostic (1.96e-2)" "unprognostic (1.81e-1)" "unprognostic (1.72e-2)" "unprognostic (8.08e-2)" 15.2 18.0 18.8 9.5 25.4 3.6 15.9 33.0 78.1 27.3 0.0 28.5 9.8 27.1 6.3 18.2 21.6 8.9 32.1 26.6 12.7 22.4 8.2 18.9 9.1 39.8 10.8 24.6 15.5 15.2 48.3 7.2 37.0 28.7 4.7 28.4 15.9 16.0 57.8 18.3 16.3 11.2 5.7 13.7 20.2 32.2 23.1 25.1 17.7 14.2 6.4 27.2 21.7 35.8 49.4 58.2 28.3 16.9 16.9 13.5 21.9 34.1 24.2 34.2 26.1 31.9 14.3 21.3 31.9 25.6 43.9 40.7 29.3 33.2 11.4 35.7 37.2 4.4 48.0 22.4 32.1 9.9 22.7 13.5 42.7 40.1 32.8 22.0 16.1 26.2 24.1 29.0 27.8 69.2 56.8 15.0 27.8 14.2 49.2 21.4 14.6 30.1 27.2 27.4 76.3 37.5 24.6 22.1 41.3 15.7 36.3 6.7 26.8 55.5 49.8 68.2 45.5 30.7 27.4 11.9 39.3 6.7 22.9 0.0 0.2 0.5 2.4 0.1 3.1 1.9 1.1 1.6 0.3 3.2 1.1 1.4 0.3 1.3 0.2 2.1 0.3 1.1 18.8 25.4 33.0 78.1 26.6 12.7 39.8 10.8 37.0 5.7 23.1 35.8 4.0 3.2 1.5 8.8 8.9 8.9 9.2 11.1 7.4 34.4 10.1 7.2 2.4 7.2 5.5 12.9 12.5 9.9 5.1 3.1 13.7 14.8 10.1 7.7 6.2 5.2 37.1 0.8 20.7 8.2 18.2 6.5 13.7 9.7 0.0 8.6 3.9 2.3 3.1 55.5 19.0 7.2 18.3 3.2 4.0 4.6 8.7 2.8 12.4 5.6 6.3 14.6 4.1 4.0 6.2 19.1 4.9 13.9 9.1 18.2 3.9 10.3 7.3 35.2 0.0 9.5 13.3 26.2 29.8 8.9 9.7 12.7 8.2 3.4 4.9 8.5 KLC4 "bA387M24.3, KNSL8" ENSG00000137171 "Kinesin light chain 4" Q9NSK0 6 43040777-43075095 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 89.9" "Cell type enhanced" "Detected in all" "Distal enterocytes: 81.9;Hepatocytes: 67.8;Paneth cells: 70.4;Proximal enterocytes: 143.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 65.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030168, HPA030169" Enhanced Approved Mitochondria,Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Mitochondria Cytosol "HPA030168: AB_10599285, HPA030169: AB_10601105" "unprognostic (2.96e-2)" "unprognostic (6.29e-2)" "unprognostic (1.83e-2)" "unprognostic (1.08e-2)" "unprognostic (3.67e-2)" "unprognostic (5.63e-3)" "unprognostic (6.36e-3)" "unprognostic (1.19e-2)" "unprognostic (4.67e-2)" "unprognostic (1.30e-1)" "unprognostic (1.47e-2)" "unprognostic (9.22e-2)" "prognostic favorable (6.99e-6)" "unprognostic (2.08e-1)" "unprognostic (3.93e-1)" "unprognostic (1.59e-1)" "unprognostic (1.06e-2)" 12.3 17.2 18.8 11.2 19.6 12.4 13.4 21.8 22.8 16.6 18.6 41.1 72.5 15.1 23.0 10.9 17.7 17.9 25.1 18.7 19.0 24.2 89.9 16.5 13.5 21.2 19.2 19.7 17.8 28.7 24.1 12.2 21.2 17.0 34.2 23.8 19.9 15.8 22.9 17.5 63.7 14.0 17.5 12.5 31.8 24.8 19.6 17.1 19.7 22.8 11.1 17.3 12.9 20.9 7.5 6.0 15.9 18.9 15.0 14.7 13.7 5.5 8.5 9.5 15.6 9.8 11.5 9.9 19.7 13.4 12.6 12.3 15.8 14.9 7.2 10.0 19.1 11.4 18.2 44.0 14.5 5.4 9.1 19.3 18.2 11.8 10.8 29.8 12.1 20.5 7.9 12.8 8.0 13.0 16.2 12.2 6.1 65.4 7.9 12.6 9.0 19.3 14.3 6.5 26.7 12.8 10.3 9.6 20.3 14.9 16.4 15.0 10.2 10.6 12.8 5.4 5.9 25.8 9.9 24.1 5.8 8.5 3.9 2.6 2.6 3.2 2.6 2.6 3.4 3.7 3.7 2.5 3.0 3.2 4.5 3.3 6.5 4.9 2.6 8.7 4.5 2.3 18.8 19.6 21.8 22.8 18.7 19.0 21.2 19.2 21.2 17.5 19.6 20.9 4.1 16.0 14.4 23.5 4.3 3.7 9.2 12.5 15.9 21.8 8.0 8.8 10.6 20.0 10.8 14.7 29.2 11.8 11.4 81.9 19.6 8.7 13.4 8.9 3.8 5.8 22.3 9.3 17.2 9.8 4.9 5.9 33.6 7.9 7.0 12.2 7.5 67.8 6.5 11.8 24.2 35.3 10.2 5.7 2.9 6.5 10.2 3.6 3.6 6.5 5.3 16.3 4.1 10.6 9.7 7.6 70.4 6.8 7.4 5.0 143.4 23.5 19.0 28.0 13.1 6.0 5.5 27.3 15.6 9.4 4.5 13.5 5.3 6.2 44.0 6.6 KLHL29 "KBTBD9, KIAA1921" ENSG00000119771 "Kelch like family member 29" Q96CT2 2 23385179-23708611 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Excitatory neurons: 146.4;Inhibitory neurons: 132.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 16.9;RH-30: 19.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049057, HPA057379" Approved Approved Mitochondria,Cytosol NA NA "Cluster 59: Non-specific - Translation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria Cytosol "HPA049057: AB_2680615, HPA057379: AB_2683422" "unprognostic (8.08e-3)" "unprognostic (2.91e-1)" "unprognostic (7.43e-3)" "unprognostic (2.65e-2)" "unprognostic (9.11e-2)" "unprognostic (1.67e-2)" "unprognostic (3.54e-3)" "unprognostic (1.16e-1)" "unprognostic (4.71e-2)" "unprognostic (2.18e-1)" "prognostic favorable (2.19e-4)" "unprognostic (2.53e-1)" "prognostic unfavorable (6.29e-4)" "unprognostic (1.12e-2)" "unprognostic (9.06e-2)" "unprognostic (7.44e-2)" "unprognostic (5.25e-4)" 6.6 9.2 3.9 2.2 4.0 0.1 5.8 0.7 8.9 5.3 3.4 8.8 0.9 6.1 1.2 2.9 4.4 3.1 2.5 5.2 3.3 4.2 2.6 3.9 2.6 2.0 2.6 2.5 1.9 2.3 10.2 3.3 2.5 7.7 1.2 7.0 3.0 4.8 10.7 5.7 3.8 3.0 3.0 5.0 3.9 0.9 3.4 1.6 1.6 2.9 1.6 4.4 5.1 4.5 1.4 1.1 7.5 3.8 7.0 4.6 12.9 7.8 6.0 3.1 2.2 0.0 0.4 5.1 2.6 3.0 16.9 0.2 1.7 6.7 2.1 0.0 8.0 0.0 6.7 0.0 2.4 0.0 9.9 3.4 8.9 4.1 11.6 1.0 5.3 0.2 0.0 0.0 1.7 0.7 1.8 0.0 3.7 0.0 2.3 0.5 19.3 0.1 5.8 2.3 11.3 2.3 1.0 0.8 4.5 3.0 0.0 0.1 5.4 3.1 14.4 6.7 2.7 0.2 0.0 0.0 11.8 0.5 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.9 4.0 0.7 8.9 5.2 3.3 2.0 2.6 2.5 3.0 3.4 4.5 1.2 6.4 5.3 6.8 0.3 4.7 10.4 2.9 7.4 8.4 0.4 6.0 2.3 4.3 1.3 1.8 27.1 1.2 0.1 0.1 0.0 1.2 1.8 3.5 5.4 2.3 4.2 0.0 146.4 0.2 0.9 3.9 0.0 3.9 0.0 0.2 0.7 0.5 0.3 1.7 132.7 0.7 0.0 0.0 0.0 0.7 5.0 0.4 1.8 7.5 0.0 1.7 0.0 5.5 4.7 0.4 0.4 4.1 0.0 1.9 0.0 1.3 1.7 26.1 6.6 6.5 6.5 0.1 1.1 2.0 5.8 0.8 0.4 0.4 0.8 1.5 LANCL3 FLJ42925 ENSG00000147036 "LanC like 3" Q6ZV70 X 37571569-37684463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 8.8;Inhibitory neurons: 20.4;Squamous epithelial cells: 10.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "basophil: 3.8" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.8" "Cell line enhanced" "Detected in some" "HEL: 11.8;HMC-1: 3.6;K-562: 3.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005470, HPA076575" Approved Approved Mitochondria NA NA "Cluster 38: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA005470: AB_2134886, HPA076575: AB_2732315" "unprognostic (6.76e-2)" "unprognostic (4.21e-2)" "unprognostic (1.52e-1)" "unprognostic (1.85e-1)" "unprognostic (5.20e-2)" "unprognostic (5.26e-2)" "unprognostic (3.60e-1)" "unprognostic (1.21e-3)" "unprognostic (1.22e-1)" "unprognostic (7.11e-2)" "unprognostic (2.81e-2)" "unprognostic (2.88e-1)" "unprognostic (7.90e-5)" "unprognostic (4.01e-3)" "unprognostic (7.93e-3)" "unprognostic (1.11e-2)" "unprognostic (2.08e-2)" 0.2 0.2 0.1 0.1 0.4 0.2 0.1 2.6 1.0 0.4 0.0 1.0 0.1 0.2 0.0 1.5 0.1 0.1 0.1 0.6 3.7 0.2 0.0 0.3 0.1 1.0 1.6 0.0 0.0 0.0 0.5 0.0 1.0 0.1 0.5 0.6 0.4 0.2 0.2 0.7 0.2 0.1 0.5 0.1 0.6 0.2 2.5 0.1 0.1 0.1 0.2 0.3 1.1 0.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.7 1.5 0.2 0.0 0.0 0.2 11.8 1.1 0.0 0.0 0.0 3.6 0.0 0.3 0.0 0.0 0.0 0.2 0.0 3.0 0.0 0.6 0.0 0.1 0.2 0.2 0.1 1.1 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.8 0.0 0.0 1.1 0.5 0.0 0.0 1.8 0.0 0.3 3.8 0.0 0.2 0.4 0.0 0.3 0.0 0.1 0.8 0.0 0.0 0.0 0.4 0.1 0.4 0.0 0.0 0.3 0.3 0.1 0.4 2.6 1.0 0.6 3.7 1.0 1.6 1.0 0.5 2.5 0.5 1.3 3.2 4.1 2.9 0.1 8.8 1.2 1.8 6.8 0.8 0.6 0.4 0.9 0.0 1.2 0.0 0.0 0.0 3.0 6.6 0.0 0.0 0.1 0.3 0.6 1.1 1.8 0.8 3.1 0.2 0.2 0.4 4.1 0.7 1.3 0.1 0.0 0.2 0.1 3.3 20.4 0.4 2.0 0.3 0.5 0.0 0.3 0.2 0.0 1.0 0.2 0.5 4.1 1.0 2.0 2.1 1.4 1.5 0.2 0.7 1.6 0.2 0.0 1.4 0.0 1.8 0.9 0.7 3.1 10.1 4.4 0.1 1.4 0.2 1.0 2.5 LGALS2 HL14 ENSG00000100079 "Galectin 2" P05162 22 37570248-37582616 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 335.5;intestine: 198.0;kidney: 153.0;pancreas: 211.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 779.2;Distal enterocytes: 695.4;Langerhans cells: 982.8;Proximal enterocytes: 2724.7;Proximal tubular cells: 1764.8;Undifferentiated cells: 749.3" "Cancer enhanced" "Detected in all" "renal cancer: 54.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 27 "classical monocyte: 1464.7;intermediate monocyte: 553.8;myeloid DC: 1207.2" "Group enriched" "Detected in all" 50 "dendritic cells: 1207.2;monocytes: 1464.7" "Group enriched" "Detected in many" 4 "CACO-2: 109.4;Hep G2: 62.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA003536, CAB025198" Enhanced Approved Nucleoplasm,Mitochondria NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria Nucleoplasm "CAB025198: , HPA003536: AB_1078936" "unprognostic (1.37e-3)" "unprognostic (4.11e-3)" "unprognostic (1.32e-3)" "unprognostic (4.32e-2)" "unprognostic (1.74e-1)" "unprognostic (2.91e-3)" "unprognostic (3.19e-1)" "unprognostic (9.92e-2)" "unprognostic (8.07e-2)" "unprognostic (2.58e-1)" "unprognostic (6.15e-2)" "unprognostic (5.19e-1)" "unprognostic (2.33e-3)" "unprognostic (1.80e-1)" "unprognostic (6.70e-2)" "unprognostic (5.01e-3)" "unprognostic (1.21e-1)" 7.5 1.4 0.6 23.5 1.4 19.2 5.4 0.2 1.1 1.8 0.2 55.0 41.2 3.6 1.0 5.2 4.4 335.5 1.6 0.5 1.0 153.0 5.0 8.6 60.7 1.6 1.2 0.9 211.5 0.2 0.1 1.7 1.4 2.2 81.1 0.1 2.1 0.7 1.9 9.9 198.0 5.2 0.4 59.2 10.7 0.6 1.1 41.3 1.0 0.7 64.0 8.2 0.5 3.4 2.8 1.5 0.9 1.0 0.0 0.0 1.1 1.7 0.0 0.0 0.0 109.4 0.1 0.4 0.3 0.0 0.3 1.7 0.0 0.0 0.0 0.2 1.1 0.0 0.0 62.5 0.3 0.0 0.0 0.4 0.0 0.0 0.0 1.1 0.0 0.0 0.5 0.0 0.0 2.8 0.0 1.0 0.4 21.2 0.3 0.0 0.9 1.3 0.0 0.0 0.0 0.3 1.7 1.9 2.4 0.5 1.6 1.7 6.4 2.0 1.0 4.3 0.8 0.0 0.2 0.3 2.7 0.2 1.3 7.7 1464.7 8.7 1.8 553.8 3.3 9.9 1.8 2.1 1207.2 2.3 2.3 1.9 26.8 2.3 39.7 9.6 3.0 981.5 0.6 1.4 0.2 1.1 0.5 1.0 1.6 1.2 1.4 0.4 1.1 3.4 1.6 6.4 3.9 0.0 16.4 17.1 0.1 0.5 0.0 0.0 13.2 7.5 0.3 779.2 1.4 29.5 0.0 0.2 7.0 695.4 127.2 26.3 0.1 0.1 0.3 2.3 73.7 4.8 0.1 206.7 0.3 3.2 5.6 0.2 2.5 0.0 0.7 1.9 26.4 0.0 0.1 413.0 0.0 100.8 982.8 0.3 0.6 150.8 24.9 0.0 164.8 0.0 4.1 0.0 0.1 291.6 331.6 0.0 0.9 0.3 2724.7 1764.8 2.1 0.0 0.0 0.3 2.3 0.0 0.4 0.1 12.4 0.3 8.6 0.0 749.3 0.3 LIAS LAS ENSG00000121897 "Lipoic acid synthetase" O43766 4 39459004-39485109 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 86.0;Late spermatids: 100.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018842, HPA019076" Approved Supported Approved Nucleoplasm,Mitochondria Yes No "Cluster 30: Non-specific - Translation" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Mitochondria "HPA018842: AB_1852864, HPA019076: AB_1852866" "unprognostic (3.61e-1)" "unprognostic (1.89e-1)" "unprognostic (8.44e-2)" "unprognostic (2.33e-1)" "unprognostic (4.87e-2)" "unprognostic (1.49e-1)" "unprognostic (8.31e-2)" "unprognostic (1.57e-1)" "unprognostic (4.19e-2)" "unprognostic (3.68e-2)" "unprognostic (2.46e-3)" "unprognostic (3.80e-2)" "prognostic favorable (4.11e-7)" "unprognostic (9.41e-3)" "unprognostic (2.35e-1)" "unprognostic (5.45e-2)" "unprognostic (6.98e-2)" 5.4 7.5 5.9 3.0 6.5 6.6 5.7 7.6 9.8 5.1 5.9 6.4 5.5 4.6 5.3 6.7 6.1 3.6 11.1 6.2 6.7 8.7 8.6 2.9 5.1 6.3 6.4 10.0 6.8 6.5 4.0 3.3 6.8 4.1 6.4 5.4 4.3 3.1 27.2 5.7 5.2 5.2 5.5 3.6 6.3 9.8 6.2 4.3 4.2 21.0 4.2 5.8 4.7 8.3 5.7 4.5 5.4 5.2 11.5 11.4 4.8 6.6 3.7 6.1 4.1 6.8 7.8 20.8 7.3 2.5 15.2 4.9 15.9 9.1 8.0 2.4 4.0 8.8 2.3 7.0 10.4 19.1 5.5 10.8 14.6 7.1 22.4 13.4 7.0 12.7 21.1 5.2 7.5 3.6 10.9 24.9 7.3 15.3 14.2 9.1 15.2 12.9 7.1 2.9 6.0 4.8 3.8 4.9 22.5 7.6 5.6 8.8 2.6 4.7 10.6 6.3 15.5 9.9 15.8 14.3 7.2 22.2 4.0 2.5 6.4 3.9 5.7 7.6 12.7 10.0 8.1 8.0 6.2 7.6 16.2 11.6 3.4 7.7 5.6 5.5 5.7 4.7 5.9 6.5 7.6 9.8 6.2 6.7 6.3 6.4 6.8 5.5 6.2 8.3 11.0 9.6 12.6 14.0 12.9 9.7 11.6 17.4 12.0 25.8 15.7 17.3 20.1 17.2 12.7 18.4 10.4 24.0 22.6 12.9 21.5 13.2 86.0 11.2 15.8 10.3 18.1 12.4 11.9 6.4 18.2 10.4 9.2 10.3 17.7 19.0 11.4 19.0 17.5 10.1 18.8 13.5 18.3 13.5 7.8 100.1 10.2 11.4 1.8 6.5 17.6 15.4 16.5 14.6 22.9 10.3 10.1 12.4 5.8 6.6 18.3 32.6 14.1 26.7 0.0 10.8 20.5 64.9 25.1 13.7 9.2 9.6 14.2 19.0 18.4 8.8 LINGO3 "LERN2, LRRN6B" ENSG00000220008 "Leucine rich repeat and Ig domain containing 3" P0C6S8 19 2289784-2292024 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 34.1" "Group enriched" "Detected in some" 5 "Bipolar cells: 39.5;Oligodendrocyte precursor cells: 17.1" "Cancer enhanced" "Detected in some" "glioma: 1.4" "Region enhanced" "Detected in all" "basal ganglia: 34.1" "Group enriched" "Detected in some" 5 "basophil: 1.3;eosinophil: 4.0;neutrophil: 1.4" "Lineage enriched" "Detected in single" 9 "granulocytes: 4.0" "Group enriched" "Detected in some" 5 "HMC-1: 17.4;RPMI-8226: 4.5" "Region enhanced" "Detected in all" "basal ganglia: 59.6" "Group enriched" "Detected in many" 8 "basal ganglia: 28.8;cerebellum: 19.6;hippocampal formation: 8.4" "HPA043781, HPA059558" Enhanced Approved Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 56: Bipolar cells - Visual perception" Mitochondria "HPA043781: AB_2678668, HPA059558: AB_2684062" "unprognostic (1.24e-1)" "unprognostic (1.00e-1)" "unprognostic (7.16e-3)" "unprognostic (3.10e-1)" "unprognostic (1.59e-1)" "unprognostic (3.61e-3)" "unprognostic (3.53e-1)" "unprognostic (7.45e-3)" "unprognostic (1.11e-2)" "unprognostic (3.19e-2)" "unprognostic (4.03e-4)" "unprognostic (2.35e-2)" "unprognostic (1.36e-2)" "unprognostic (1.79e-1)" "unprognostic (5.74e-2)" "unprognostic (1.05e-1)" "unprognostic (4.14e-2)" 0.3 0.2 4.6 1.2 34.1 1.1 0.2 9.3 14.4 0.2 0.0 0.6 0.2 0.3 0.0 0.3 0.3 0.0 0.1 4.6 1.2 0.2 0.2 0.9 1.1 5.1 1.8 0.1 0.2 0.0 0.4 0.0 4.1 0.4 0.0 0.6 0.3 0.0 0.1 0.2 5.0 0.0 2.6 6.3 0.5 0.4 7.6 0.0 0.3 0.0 0.0 0.4 0.2 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.0 2.0 17.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 2.4 0.2 0.0 0.1 1.7 0.0 4.5 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 1.3 0.0 4.0 0.1 0.0 0.2 0.3 0.0 0.1 0.0 0.4 0.0 0.0 1.4 0.1 0.0 0.0 0.3 0.0 4.6 34.1 9.3 14.4 4.6 1.2 5.1 1.8 4.1 2.6 7.6 2.7 0.0 0.0 0.0 1.6 3.1 0.1 0.0 0.0 0.0 39.5 0.2 0.6 0.7 0.0 0.0 0.0 4.2 0.0 2.0 0.0 0.0 0.1 0.4 0.0 0.0 0.3 0.0 0.4 5.1 0.0 0.2 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.2 3.3 3.0 0.0 0.0 2.2 0.6 0.0 0.0 0.8 0.0 1.9 1.3 0.1 5.2 17.1 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.9 1.1 0.0 0.0 0.0 1.0 0.0 0.2 0.0 LRIT3 "CSNB1F, FIGLER4, FLJ44691" ENSG00000183423 "Leucine rich repeat, Ig-like and transmembrane domains 3" Q3SXY7 4 109848107-109872315 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Sensory transduction, Vision" "Congenital stationary night blindness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 22 "retina: 17.6" "Group enriched" "Detected in some" 6 "Cone photoreceptor cells: 33.3;Muller glia cells: 10.2;Rod photoreceptor cells: 9.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA013454 Enhanced Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 77: Retina - Visual perception" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Mitochondria, Cytosol" "HPA013454: AB_1853277" "unprognostic (5.41e-2)" "unprognostic (6.82e-2)" "unprognostic (4.20e-2)" "unprognostic (6.50e-2)" "unprognostic (3.42e-1)" "unprognostic (7.67e-3)" "unprognostic (1.54e-1)" "unprognostic (5.25e-2)" "unprognostic (3.16e-2)" "unprognostic (4.49e-2)" "unprognostic (6.92e-3)" "unprognostic (3.34e-3)" "unprognostic (2.14e-1)" "unprognostic (4.01e-2)" "unprognostic (1.69e-1)" "unprognostic (1.35e-1)" "unprognostic (1.14e-2)" 0.2 0.2 0.4 0.0 0.5 0.1 0.3 0.3 0.6 0.4 0.2 0.2 0.0 0.2 0.3 0.2 0.3 0.0 0.1 0.4 0.2 0.7 0.3 0.2 0.1 0.3 0.3 0.2 0.3 0.0 0.2 0.0 0.4 0.3 0.0 17.6 0.2 0.1 0.3 0.6 0.2 0.0 0.2 0.3 0.2 0.5 0.3 0.1 0.3 0.0 0.0 0.3 0.2 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.3 0.6 0.4 0.2 0.3 0.3 0.4 0.2 0.3 0.5 0.0 0.0 0.0 2.3 0.1 0.0 0.0 0.0 0.0 1.2 0.2 0.1 0.1 0.0 0.0 0.0 33.3 0.0 0.0 0.0 1.9 0.0 0.2 0.1 0.0 0.0 0.0 0.0 2.7 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 2.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.0 0.0 10.2 0.0 0.5 1.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 9.6 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 LRP12 "FLJ12929, ST7" ENSG00000147650 "LDL receptor related protein 12" Q9Y561 8 104489231-104589258 "Disease related genes, Human disease related genes, Predicted membrane proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 42.7;Excitatory neurons: 78.7;Inhibitory neurons: 53.7;Oligodendrocyte precursor cells: 64.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "basophil: 47.0" "Lineage enriched" "Detected in many" 32 "granulocytes: 47.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017245 Uncertain Approved "Nucleoli fibrillar center,Plasma membrane,Mitochondria" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli fibrillar center, Plasma membrane, Mitochondria" "HPA017245: AB_1857532" "unprognostic (2.17e-1)" "unprognostic (6.80e-2)" "unprognostic (2.20e-1)" "prognostic unfavorable (2.67e-4)" "unprognostic (2.07e-1)" "unprognostic (2.15e-3)" "unprognostic (4.87e-4)" "unprognostic (2.96e-2)" "unprognostic (3.96e-1)" "unprognostic (4.59e-2)" "unprognostic (1.32e-1)" "unprognostic (3.39e-2)" "unprognostic (9.89e-2)" "unprognostic (7.56e-3)" "unprognostic (4.88e-2)" "unprognostic (1.45e-1)" "unprognostic (4.05e-3)" 5.7 4.7 5.1 3.9 8.8 2.2 4.3 4.7 9.4 6.4 3.1 4.8 3.1 16.5 4.0 4.1 5.8 7.5 13.6 13.8 5.3 6.5 1.5 4.6 1.6 1.8 2.3 6.1 4.5 10.0 3.1 5.3 1.1 6.5 4.8 6.1 3.8 5.9 9.3 3.1 3.0 18.5 2.4 3.7 2.8 4.9 3.1 12.9 6.8 17.2 2.3 7.6 3.2 3.9 18.5 10.6 21.1 37.1 23.4 18.4 4.7 51.5 51.3 17.6 24.6 2.4 17.7 0.0 20.2 49.0 21.2 8.1 8.6 22.0 37.7 34.3 8.2 28.7 4.7 0.8 14.4 0.4 22.1 24.8 15.4 29.5 23.7 63.4 9.1 21.9 6.2 0.0 63.9 3.0 26.5 0.6 5.3 1.6 18.2 2.1 20.5 4.0 13.9 0.8 27.0 16.4 16.4 0.7 44.6 15.8 5.0 5.6 25.7 48.1 31.0 15.7 33.6 23.8 20.2 0.2 25.9 0.0 53.9 47.0 0.3 5.8 0.2 0.8 1.4 0.0 1.0 0.1 0.1 0.0 0.2 0.2 0.2 0.8 0.5 0.4 0.1 0.4 5.1 8.8 4.7 9.4 13.8 5.3 1.8 2.3 1.1 2.4 3.1 3.9 4.4 16.0 2.2 42.7 0.2 11.5 6.3 12.3 10.8 17.5 3.9 4.3 11.7 7.2 5.2 14.7 6.2 0.2 1.7 2.0 0.0 4.6 4.3 4.4 16.4 5.9 14.4 2.5 78.7 4.5 0.5 12.6 1.5 5.5 8.2 10.9 4.2 0.8 5.3 28.6 53.7 2.5 10.2 7.9 14.3 2.7 8.7 8.2 7.2 9.4 6.1 3.1 1.0 64.3 25.2 5.1 0.3 9.1 0.1 7.7 1.5 3.8 5.3 8.3 6.6 8.2 11.3 8.5 12.0 3.2 10.9 0.3 3.9 4.5 2.3 5.2 LRP2 "DBS, gp330" ENSG00000081479 "LDL receptor related protein 2" P98164 2 169127109-169362534 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Endocytosis, Hearing, Neurogenesis, Transport" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 70.5;kidney: 34.8;parathyroid gland: 44.7;retina: 29.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 87.6;Cytotrophoblasts: 63.2;Oligodendrocytes: 300.1;Proximal tubular cells: 283.9" "Cancer enhanced" "Detected in many" "renal cancer: 29.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "AF22: 39.4;CACO-2: 64.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA005980, HPA064792" Enhanced Approved Vesicles,Mitochondria No NA 74000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Mitochondria" "HPA005980: AB_1079278, HPA064792: AB_2685353" "unprognostic (1.87e-1)" "unprognostic (1.04e-3)" "unprognostic (1.32e-3)" "unprognostic (3.65e-3)" "unprognostic (3.18e-2)" "unprognostic (1.60e-2)" "unprognostic (1.64e-3)" "unprognostic (2.99e-1)" "unprognostic (1.94e-1)" "unprognostic (1.39e-1)" "unprognostic (4.09e-2)" "unprognostic (4.38e-1)" "prognostic favorable (3.43e-5)" "unprognostic (1.37e-1)" "unprognostic (4.21e-1)" "unprognostic (2.44e-2)" "unprognostic (1.62e-2)" 1.5 0.0 5.5 0.0 23.4 0.1 9.6 18.9 13.5 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.2 7.5 14.6 34.8 0.3 1.2 0.0 30.5 17.5 0.0 0.0 44.7 0.1 7.5 31.9 0.0 0.0 29.3 0.9 0.0 0.1 0.1 0.0 0.0 14.5 0.0 0.0 0.2 18.7 0.0 17.3 0.0 0.0 0.0 0.0 70.5 0.0 0.0 39.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 64.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 4.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.2 0.0 0.5 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 23.4 18.9 13.5 7.5 14.6 30.5 17.5 31.9 14.5 18.7 70.5 0.2 6.4 43.7 1.0 3.0 0.3 0.2 0.0 0.0 2.8 22.9 15.1 2.1 2.8 2.5 3.7 87.6 63.2 0.2 0.0 17.6 0.0 3.1 0.1 0.1 0.5 0.0 0.0 1.8 0.0 2.2 1.8 0.0 0.1 2.5 0.0 0.0 0.8 5.1 0.0 1.2 0.0 0.0 0.0 0.0 1.0 0.0 2.5 0.0 1.9 0.0 33.1 0.0 1.5 300.1 0.0 0.0 0.0 0.0 0.0 0.0 283.9 2.2 19.5 0.0 0.0 0.3 0.1 0.8 0.0 0.0 23.1 1.7 0.0 0.0 0.2 LRRC28 "FLJ34269, FLJ45242, MGC24976" ENSG00000168904 "Leucine rich repeat containing 28" Q86X40 15 99251362-99390729 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 47.1" "Cell type enhanced" "Detected in many" "Early spermatids: 159.2;Excitatory neurons: 127.4;Late spermatids: 406.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039378, HPA040784, HPA066130" Approved Approved "Nucleoplasm,Golgi apparatus,Mitochondria" No No "Cluster 2: Granulocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 21: OE19 - Mitochondria" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Golgi apparatus, Mitochondria" "HPA039378: AB_2676476, HPA040784: AB_2677135, HPA066130: AB_2685623" "unprognostic (4.84e-2)" "prognostic favorable (1.41e-4)" "unprognostic (2.82e-3)" "unprognostic (9.86e-2)" "unprognostic (2.20e-1)" "unprognostic (1.47e-1)" "unprognostic (8.02e-2)" "unprognostic (1.02e-1)" "unprognostic (1.22e-1)" "prognostic favorable (9.97e-5)" "unprognostic (2.62e-1)" "unprognostic (1.21e-1)" "unprognostic (5.89e-2)" "unprognostic (8.37e-2)" "unprognostic (3.95e-1)" "unprognostic (1.65e-3)" "unprognostic (1.41e-1)" 8.1 7.8 4.4 4.4 5.1 8.6 6.4 4.5 5.8 6.1 4.3 8.0 16.9 5.8 7.4 9.7 4.8 9.1 9.7 5.3 3.9 19.4 47.1 5.3 6.9 3.7 3.5 4.9 19.5 9.4 4.1 6.1 3.5 5.3 9.7 6.8 6.1 6.6 18.3 10.4 16.5 7.9 3.3 4.9 8.2 28.5 3.9 22.6 6.6 18.4 9.4 6.5 6.3 4.4 4.0 9.8 9.5 12.3 13.2 18.7 4.0 4.2 11.9 7.1 8.3 7.4 8.6 8.2 7.6 10.1 8.7 8.8 7.0 13.5 10.3 5.0 10.2 5.5 4.0 7.7 11.7 5.5 8.6 11.1 18.2 6.7 13.4 16.0 22.7 13.0 4.9 8.1 14.9 8.0 15.2 8.9 4.0 31.2 3.7 9.3 8.0 7.6 15.1 12.8 4.3 5.5 10.1 5.4 16.4 14.4 8.4 10.2 8.3 7.0 4.8 5.4 8.4 15.9 24.1 5.1 8.8 5.4 13.3 23.4 9.3 32.0 7.2 7.8 5.8 6.2 6.7 7.7 8.4 5.8 6.2 5.4 5.0 5.1 8.0 6.9 10.4 6.1 4.4 5.1 4.5 5.8 5.3 3.9 3.7 3.5 3.5 3.3 3.9 4.4 13.2 16.0 4.1 29.0 13.5 13.8 14.5 14.5 12.5 19.9 8.9 12.4 13.4 12.8 11.0 11.0 22.9 17.5 11.4 18.6 27.4 12.7 159.2 7.4 8.4 11.9 9.1 12.4 127.4 29.5 22.6 8.5 15.8 6.5 2.5 15.0 12.8 37.0 19.3 21.9 86.8 16.0 20.3 19.8 20.1 406.4 12.8 15.3 14.2 37.5 19.1 14.4 14.4 63.3 63.0 14.8 24.2 8.6 14.7 8.4 72.3 74.1 10.1 19.8 0.0 10.7 11.7 77.1 39.0 15.1 15.8 13.0 11.3 18.0 19.5 15.4 LRRC57 FLJ36812 ENSG00000180979 "Leucine rich repeat containing 57" Q8N9N7 15 42537820-42548802 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 60.5;Rod photoreceptor cells: 87.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA040894 Approved Approved Mitochondria,Cytosol NA NA 26000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 46: Photoreceptor cells - Phototransduction" "Mitochondria, Cytosol" "HPA040894: AB_10794996" "unprognostic (8.99e-2)" "unprognostic (1.80e-1)" "unprognostic (1.42e-2)" "unprognostic (1.68e-1)" "unprognostic (1.84e-2)" "unprognostic (4.77e-2)" "unprognostic (4.16e-2)" "unprognostic (4.78e-2)" "unprognostic (2.57e-1)" "unprognostic (1.32e-1)" "unprognostic (3.31e-2)" "unprognostic (3.73e-2)" "prognostic favorable (2.15e-4)" "unprognostic (7.45e-2)" "unprognostic (7.23e-2)" "unprognostic (2.35e-1)" "unprognostic (1.05e-2)" 7.7 7.3 4.8 5.5 4.6 22.0 7.5 4.8 8.5 7.3 3.3 9.3 6.5 7.7 5.5 9.6 8.3 5.3 6.9 6.1 3.1 8.0 6.1 8.6 6.6 3.6 3.4 8.6 7.3 14.0 6.0 7.9 4.1 6.6 10.7 14.9 8.0 5.8 6.0 9.6 8.1 7.3 3.2 6.7 7.8 5.7 3.7 9.6 7.0 6.9 7.4 6.8 8.6 5.4 14.7 11.0 19.5 13.8 16.5 12.7 9.7 20.5 11.2 14.7 15.4 23.3 11.0 6.8 13.8 16.9 16.5 22.7 13.2 16.7 14.7 12.8 12.2 27.7 23.6 10.7 14.7 17.8 15.0 14.0 22.8 13.2 17.1 10.1 23.7 17.3 21.9 14.5 13.6 6.6 9.8 7.5 4.6 26.6 8.5 15.1 19.6 10.5 9.8 24.4 9.8 11.9 24.8 16.3 11.8 12.7 16.1 19.6 24.3 16.5 11.4 17.5 15.5 11.9 36.4 29.0 8.9 16.4 21.0 36.9 9.7 32.0 7.4 14.6 9.3 5.8 7.2 7.2 10.2 7.1 5.8 7.3 12.2 16.9 19.3 5.9 8.5 6.9 4.8 4.6 4.8 8.5 6.1 3.1 3.6 3.4 4.1 3.2 3.7 5.4 16.3 9.6 10.8 6.8 10.4 5.7 13.6 6.5 6.8 13.6 9.6 8.1 11.1 15.7 7.3 9.2 60.5 11.6 18.8 16.4 13.7 10.9 18.7 13.5 13.8 17.3 12.5 15.8 17.1 9.8 19.3 12.7 9.2 13.2 14.5 10.2 19.2 7.5 14.1 20.2 8.8 13.1 6.1 14.2 4.8 20.0 9.6 13.1 7.2 7.5 21.9 21.1 20.6 11.6 8.3 15.2 15.9 16.1 8.4 12.4 15.2 8.4 14.8 87.4 6.6 16.9 10.1 7.8 6.4 11.4 5.5 15.9 11.3 18.4 12.2 12.8 LRRD1 IMAGE:4798971 ENSG00000240720 "Leucine rich repeats and death domain containing 1" A4D1F6 7 92141643-92179531 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 16.5" "Group enriched" "Detected in some" 90 "Early spermatids: 258.1;Late spermatids: 869.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA055670, HPA079440" Enhanced Approved Vesicles,Mitochondria NA NA "Cluster 17: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria Vesicles "HPA055670: , HPA079440: " "unprognostic (1.11e-1)" "unprognostic (1.49e-1)" "unprognostic (3.72e-1)" "unprognostic (4.01e-2)" "unprognostic (1.93e-1)" "unprognostic (1.12e-1)" "unprognostic (5.39e-2)" "unprognostic (1.14e-1)" "unprognostic (3.29e-1)" "unprognostic (1.27e-2)" "unprognostic (1.56e-2)" "unprognostic (1.81e-3)" "unprognostic (1.77e-1)" "unprognostic (7.67e-2)" "unprognostic (2.02e-1)" "unprognostic (3.13e-3)" 0.0 0.0 0.4 0.0 0.5 0.3 0.1 1.7 0.8 0.1 0.0 0.0 0.1 0.1 0.4 0.0 0.1 0.2 0.1 0.5 0.9 0.0 0.0 0.0 0.1 0.6 0.4 0.1 0.0 0.0 0.1 0.0 0.8 0.1 0.0 0.5 0.1 0.0 0.1 0.3 0.1 0.1 0.2 0.1 0.0 16.5 0.8 0.0 0.1 0.0 0.1 0.0 0.0 1.1 0.1 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.2 0.0 0.0 0.6 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.4 0.1 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.2 0.1 0.1 0.0 0.2 0.0 0.1 0.0 0.6 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.4 0.1 0.1 0.1 0.2 0.0 0.4 0.5 1.7 0.8 0.5 0.9 0.6 0.4 0.8 0.2 0.8 1.1 0.1 0.0 0.6 1.6 0.0 0.3 0.5 0.0 0.0 0.6 0.2 0.0 0.2 0.0 0.7 0.0 0.0 0.1 0.3 0.1 0.0 0.0 258.1 0.1 0.6 0.3 0.0 0.0 1.7 0.0 0.1 0.3 0.0 0.3 1.3 0.4 0.0 0.0 0.1 1.7 2.8 0.0 0.0 0.0 0.7 869.3 4.7 0.5 0.0 1.0 0.0 0.3 0.0 1.5 1.4 0.0 0.0 3.0 0.0 0.4 0.1 0.1 1.5 0.9 0.0 1.2 0.3 6.2 2.6 0.0 0.3 0.0 0.5 0.3 0.1 0.3 LRRIQ4 LRRC64 ENSG00000188306 "Leucine rich repeats and IQ motif containing 4" A6NIV6 3 169821922-169837775 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 2.9" "Group enriched" "Detected in some" 17 "Early spermatids: 42.8;Late spermatids: 27.0" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RT4: 1.6;T-47d: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA036271, HPA036706" Uncertain Approved Mitochondria NA NA "Cluster 45: Intestine - Brush border" "Cluster 6: T47d - Mammary gland" "Cluster 29: Early spermatids - Spermatogenesis" Mitochondria "HPA036271: , HPA036706: AB_2675264" "unprognostic (5.09e-2)" "unprognostic (8.85e-2)" "unprognostic (2.55e-1)" "unprognostic (1.30e-4)" "unprognostic (5.26e-3)" "unprognostic (2.32e-2)" "unprognostic (2.04e-1)" "unprognostic (2.31e-1)" "unprognostic (1.29e-1)" "unprognostic (1.17e-1)" "unprognostic (9.72e-2)" "unprognostic (1.42e-1)" "unprognostic (2.12e-1)" "unprognostic (7.47e-2)" "unprognostic (1.55e-1)" "unprognostic (6.74e-2)" "unprognostic (4.56e-3)" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 2.9 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.6 0.1 0.0 0.5 0.0 0.2 0.0 0.1 0.7 0.0 0.9 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.2 0.3 0.0 0.0 0.0 1.6 0.6 0.2 0.0 0.1 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 42.8 0.3 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 27.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.3 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 LUC7L "hLuc7B1, Luc7, LUC7B1" ENSG00000007392 "LUC7 like" Q9NQ29 16 188969-229463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056424, HPA069321" Supported Approved Nucleoplasm,Mitochondria NA NA 14000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 52: Non-specific - Transcription" Nucleoplasm Mitochondria "HPA056424: AB_2683126, HPA069321: AB_2686119" "unprognostic (9.55e-3)" "unprognostic (2.01e-1)" "unprognostic (3.23e-2)" "unprognostic (5.61e-2)" "unprognostic (7.81e-2)" "unprognostic (2.60e-2)" "unprognostic (8.01e-3)" "unprognostic (4.31e-2)" "unprognostic (7.60e-2)" "unprognostic (2.35e-1)" "prognostic favorable (1.30e-4)" "unprognostic (1.57e-2)" "prognostic unfavorable (2.59e-4)" "unprognostic (1.33e-1)" "unprognostic (2.48e-1)" "unprognostic (2.02e-1)" "unprognostic (2.02e-3)" 32.9 47.3 46.0 16.5 46.5 24.0 32.2 47.8 62.9 58.9 46.4 42.8 17.1 40.8 28.2 31.8 40.8 19.4 33.5 46.8 47.1 54.6 43.0 31.9 27.6 45.6 44.9 48.3 48.9 14.9 58.8 18.4 45.4 68.6 13.8 19.6 27.4 18.5 23.3 26.0 40.7 16.2 43.8 63.7 39.2 41.8 45.6 20.3 72.9 12.9 16.9 34.7 36.7 48.3 14.6 62.5 65.1 25.0 24.0 18.8 29.2 26.2 19.7 40.6 29.7 65.8 16.7 27.1 33.5 14.8 22.2 18.5 77.5 23.5 41.2 46.7 53.9 31.7 48.2 77.7 27.4 37.8 34.2 17.0 26.8 33.9 13.3 35.3 31.8 22.1 38.7 16.9 33.8 68.6 60.4 63.8 98.1 32.2 30.0 52.3 28.6 27.8 59.1 15.4 38.8 43.1 28.3 19.6 25.9 38.4 25.2 20.3 27.2 30.5 45.6 13.1 32.2 18.2 25.6 28.2 9.3 26.4 28.1 0.3 9.3 3.9 6.3 11.0 5.1 6.4 6.1 6.4 10.2 2.8 3.5 2.7 1.1 4.5 13.3 11.4 7.5 5.9 46.0 46.5 47.8 62.9 46.8 47.1 45.6 44.9 45.4 43.8 45.6 48.3 64.2 51.3 67.9 59.4 46.9 53.2 39.9 36.4 47.8 48.9 33.1 32.8 22.3 12.8 46.7 23.9 37.5 30.1 63.1 27.2 11.7 35.8 56.7 48.9 81.6 48.2 42.3 26.9 56.7 21.1 42.9 44.4 52.5 55.5 41.1 66.9 26.0 12.7 24.3 45.4 54.0 26.0 28.5 16.6 54.9 21.5 32.6 34.0 39.2 30.0 32.2 24.4 17.5 54.8 40.6 25.8 28.0 32.4 47.4 43.5 27.9 15.5 34.6 59.7 26.3 50.0 50.4 82.1 56.7 29.3 54.3 49.9 45.4 42.5 26.2 37.6 LYSMD2 MGC35274 ENSG00000140280 "LysM domain containing 2" Q8IV50 15 51723011-51751585 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 164.4;monocytes: 97.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-937: 77.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040460 Approved Approved "Nuclear bodies,Mitochondria" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 57: B-cells - Immune response" Mitochondria "Nuclear bodies" "HPA040460: AB_10794874" "unprognostic (7.71e-3)" "unprognostic (2.69e-1)" "unprognostic (3.38e-1)" "unprognostic (1.86e-1)" "unprognostic (1.11e-2)" "unprognostic (1.99e-2)" "unprognostic (1.01e-1)" "unprognostic (1.60e-1)" "unprognostic (1.85e-1)" "unprognostic (3.98e-1)" "unprognostic (4.17e-3)" "unprognostic (6.86e-2)" "unprognostic (1.58e-2)" "unprognostic (5.03e-1)" "unprognostic (4.69e-2)" "unprognostic (2.01e-1)" "unprognostic (1.10e-1)" 11.6 19.7 33.0 22.2 34.0 15.1 8.7 30.9 42.0 10.4 22.3 12.7 15.8 10.7 11.1 8.7 10.9 11.4 7.1 33.8 39.6 11.5 21.1 14.4 29.0 34.1 33.2 8.5 12.9 10.7 22.8 9.5 39.3 9.4 9.7 7.6 7.3 13.8 18.3 5.6 13.6 11.7 32.4 21.3 12.0 11.0 35.0 17.9 8.1 13.1 25.7 12.8 8.8 29.4 14.6 10.6 1.7 13.2 4.4 8.4 0.1 16.8 9.2 20.0 25.8 1.3 13.0 56.9 2.4 9.0 23.1 21.0 11.0 11.1 14.0 55.1 5.4 15.9 8.9 0.2 9.3 38.2 6.9 8.4 22.0 8.2 8.6 9.0 12.1 20.5 0.7 0.0 6.5 21.0 14.8 47.6 4.6 0.6 14.5 23.1 0.2 20.6 19.9 11.5 45.3 11.5 16.2 0.4 29.8 2.5 11.7 28.5 7.8 19.8 11.1 20.9 23.7 0.0 0.0 0.2 10.1 77.4 15.1 0.3 39.5 76.6 29.8 48.8 42.3 47.0 29.1 36.3 33.4 49.7 35.6 29.4 112.5 34.9 62.0 54.4 19.4 40.4 33.0 34.0 30.9 42.0 33.8 39.6 34.1 33.2 39.3 32.4 35.0 29.4 45.7 3.2 4.8 18.3 70.8 19.4 31.2 8.0 20.5 16.7 17.5 23.4 3.3 22.8 6.4 14.7 0.0 1.2 89.1 4.1 25.4 16.7 164.4 2.6 2.8 32.3 79.8 17.2 25.4 18.3 0.8 15.6 15.3 0.9 12.7 4.3 27.8 14.6 38.0 32.0 28.7 16.2 8.2 46.4 24.7 71.2 16.1 49.0 7.2 23.4 97.4 7.0 45.3 15.1 7.3 10.8 17.1 15.8 5.1 38.5 32.6 29.0 9.9 4.1 26.3 14.1 24.0 5.0 8.3 31.7 16.2 0.8 51.3 12.4 21.2 24.6 M1AP "C2orf65, D6Mm5e, SPATA37" ENSG00000159374 "Meiosis 1 associated protein" Q8TC57 2 74557883-74648338 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 8.0" "Group enriched" "Detected in some" 4 "Spermatocytes: 16.2;Spermatogonia: 22.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "NTERA-2: 2.1;RT4: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045420, HPA059302" Uncertain Approved Nucleoli,Mitochondria NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 5: NTERA-2 - Transcription" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Mitochondria Nucleoli "HPA045420: AB_10961177, HPA059302: AB_2683972" "unprognostic (1.76e-1)" "unprognostic (6.58e-3)" "unprognostic (1.26e-2)" "unprognostic (2.87e-1)" "unprognostic (9.15e-2)" "unprognostic (1.35e-3)" "unprognostic (1.86e-1)" "unprognostic (2.17e-3)" "unprognostic (3.42e-1)" "unprognostic (2.37e-1)" "unprognostic (2.00e-1)" "unprognostic (2.15e-2)" "unprognostic (6.11e-2)" "unprognostic (7.74e-2)" "unprognostic (1.87e-1)" "unprognostic (1.67e-1)" "unprognostic (1.46e-1)" 0.3 0.2 1.1 0.1 0.7 2.5 0.5 0.0 1.2 2.5 0.8 0.1 0.1 1.1 0.3 0.1 2.6 0.1 0.0 1.1 0.6 1.0 0.0 0.4 0.1 0.0 0.2 0.0 0.3 1.3 1.8 0.1 0.0 0.1 0.0 0.5 0.9 0.3 0.0 0.0 0.0 0.1 0.2 0.1 0.4 8.0 1.7 0.6 2.0 0.0 0.3 0.3 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.3 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.7 0.0 1.2 1.1 0.6 0.0 0.2 0.0 0.2 1.7 0.3 0.1 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.3 0.4 0.4 0.0 0.1 3.7 0.0 0.5 0.1 0.2 0.0 0.3 3.1 2.2 0.1 0.0 0.0 0.4 3.1 0.0 1.6 0.0 0.0 0.9 0.0 0.0 0.0 0.1 3.8 0.0 1.0 0.8 0.0 1.6 0.8 3.9 0.0 2.0 0.0 2.8 0.4 0.5 0.0 0.0 0.4 0.2 0.0 0.0 0.5 0.2 0.0 0.1 1.8 1.4 0.0 0.1 0.0 16.2 22.5 0.0 0.0 0.3 0.1 0.0 0.1 0.1 MACC1 "7A5, SH3BP4L" ENSG00000183742 "MET transcriptional regulator MACC1" Q6ZN28 7 20134655-20217404 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Growth factor, Mitogen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 11.7" "Cell type enhanced" "Detected in many" "Club cells: 102.4;Glandular and luminal cells: 100.5;Pancreatic endocrine cells: 136.4;Respiratory ciliated cells: 93.4;Urothelial cells: 238.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 98.0;CAPAN-2: 22.2;HaCaT: 66.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA020081, HPA020103, HPA029476, CAB068194" Supported Approved Mitochondria NA NA "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Mitochondria "CAB068194: AB_2665682, HPA020081: AB_1844386, HPA020103: AB_1844387, HPA029476: AB_10610136" "unprognostic (1.59e-2)" "unprognostic (1.88e-1)" "unprognostic (3.43e-2)" "prognostic unfavorable (1.56e-5)" "unprognostic (2.26e-1)" "unprognostic (1.42e-2)" "unprognostic (7.01e-2)" "unprognostic (2.52e-2)" "unprognostic (2.05e-1)" "unprognostic (2.43e-2)" "unprognostic (2.43e-3)" "unprognostic (1.03e-1)" "prognostic favorable (5.71e-9)" "unprognostic (4.49e-2)" "unprognostic (2.91e-1)" "unprognostic (1.78e-1)" "unprognostic (6.93e-3)" 0.6 2.3 1.4 1.3 0.6 1.0 4.3 1.0 1.4 2.9 0.0 2.7 9.8 0.8 0.7 8.8 0.9 2.9 0.2 1.0 0.3 6.6 0.4 5.4 0.9 1.1 0.7 0.1 3.3 0.4 0.3 0.2 1.4 1.0 3.2 0.6 5.6 2.6 0.1 2.9 11.7 0.3 0.2 0.8 4.9 0.5 0.9 0.6 1.1 0.0 3.5 3.9 3.0 1.3 98.0 0.4 0.4 0.0 0.1 0.2 0.9 0.1 0.0 0.0 0.0 21.6 22.2 13.8 1.0 0.0 0.1 66.9 0.2 0.9 0.0 0.1 0.4 13.0 0.3 0.0 0.0 5.5 0.4 0.0 0.7 0.0 0.1 0.2 0.1 0.3 14.2 6.5 0.1 8.1 0.0 1.4 1.0 19.1 0.1 0.0 0.6 10.5 16.5 6.7 0.3 0.5 0.0 7.5 0.1 0.4 3.9 0.2 0.4 0.2 0.2 0.1 0.2 20.1 1.0 5.0 0.1 0.7 0.2 0.2 0.1 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.2 0.1 0.0 0.1 1.4 0.6 1.0 1.4 1.0 0.3 1.1 0.7 1.4 0.2 0.9 1.3 4.1 70.5 57.4 0.7 6.5 2.8 75.8 11.3 2.8 3.3 22.2 7.5 0.6 24.3 102.4 40.5 2.1 0.8 2.2 16.9 7.9 51.4 2.9 59.6 16.3 4.1 38.7 4.2 1.0 63.8 0.2 5.7 18.3 100.5 12.6 0.4 2.2 0.8 4.4 1.7 2.9 19.5 34.6 0.9 3.8 1.2 2.1 11.0 1.8 0.0 8.4 0.3 1.0 0.0 0.9 136.4 20.4 2.6 6.3 72.8 40.2 17.5 93.4 1.3 0.0 0.8 3.6 0.4 0.6 13.2 4.0 0.3 2.9 0.3 17.5 238.8 MAIP1 "C2orf47, DKFZp666A212, FLJ22555" ENSG00000162972 "Matrix AAA peptidase interacting protein 1" Q8WWC4 2 199955317-200008540 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 30.0;Distal tubular cells: 37.2;Ductal cells: 31.4;Exocrine glandular cells: 28.0;Extravillous trophoblasts: 33.8;Proximal tubular cells: 84.2;Syncytiotrophoblasts: 32.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064013, HPA072231" Approved Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA064013: AB_2685175, HPA072231: AB_2732196" "unprognostic (4.89e-2)" "unprognostic (7.36e-2)" "unprognostic (7.40e-3)" "prognostic unfavorable (2.14e-4)" "unprognostic (2.74e-1)" "prognostic unfavorable (3.81e-4)" "unprognostic (4.86e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (1.87e-4)" "unprognostic (1.02e-3)" "unprognostic (7.03e-2)" "unprognostic (2.00e-2)" "unprognostic (5.21e-3)" "unprognostic (1.45e-1)" "unprognostic (1.94e-1)" "unprognostic (1.63e-1)" "unprognostic (2.70e-2)" 11.1 16.1 7.0 8.3 7.2 18.7 11.3 10.1 8.4 7.3 6.5 14.4 21.1 7.8 7.4 11.7 9.0 8.1 16.6 7.5 6.5 31.1 46.2 7.4 8.8 6.7 6.5 7.5 10.3 12.2 5.8 9.3 7.3 9.1 13.1 7.2 9.6 9.0 22.2 9.7 16.8 7.5 7.1 8.5 12.6 4.9 6.8 9.3 9.7 16.8 10.4 9.2 8.2 8.6 23.9 21.8 19.3 15.2 16.8 16.9 44.5 21.1 20.2 30.7 29.3 59.5 21.0 15.7 29.6 14.6 25.4 25.8 28.7 22.7 28.8 24.7 32.9 26.4 18.5 54.7 22.6 36.7 18.0 18.1 18.3 20.3 21.9 17.6 19.7 29.9 35.2 19.8 20.2 31.4 27.8 34.0 24.7 25.2 51.6 26.4 22.9 31.6 36.6 30.5 21.8 15.1 21.7 24.4 40.1 24.3 21.6 22.1 17.6 17.9 25.6 15.6 23.7 18.8 23.6 33.7 27.0 21.1 18.7 9.9 12.9 9.4 10.8 12.8 13.3 13.8 10.6 7.7 16.8 14.1 10.0 8.6 2.0 8.9 12.6 13.5 13.9 8.2 7.0 7.2 10.1 8.4 7.5 6.5 6.7 6.5 7.3 7.1 6.8 8.6 11.7 9.6 14.9 0.0 2.1 0.0 0.0 0.0 0.0 0.0 10.8 14.1 0.0 0.0 5.0 3.7 0.0 30.0 7.0 0.0 37.2 31.4 0.0 10.0 10.2 6.1 0.0 0.0 0.0 28.0 33.8 6.2 0.0 11.9 3.8 12.2 0.0 0.0 23.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 6.7 0.0 0.0 0.0 0.0 21.2 0.0 0.0 1.3 0.0 0.0 84.2 5.8 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 32.0 4.0 18.3 0.0 0.0 MANBAL dJ1141E15.2 ENSG00000101363 "Mannosidase beta like" Q9NQG1 20 37289638-37317260 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052348 Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" Mitochondria Nucleoplasm "HPA052348: AB_2681795" "unprognostic (1.86e-2)" "unprognostic (9.15e-2)" "unprognostic (1.85e-1)" "unprognostic (2.45e-2)" "unprognostic (3.12e-1)" "unprognostic (2.21e-3)" "prognostic unfavorable (7.07e-4)" "unprognostic (2.37e-1)" "unprognostic (1.23e-1)" "unprognostic (9.61e-2)" "unprognostic (2.83e-1)" "unprognostic (3.43e-1)" "prognostic favorable (3.62e-4)" "unprognostic (1.06e-1)" "unprognostic (1.86e-1)" "unprognostic (8.03e-2)" "unprognostic (2.70e-2)" 51.5 70.5 68.6 23.4 68.2 7.3 51.6 67.3 76.3 67.5 68.8 92.7 35.0 86.1 57.1 64.4 71.6 30.6 43.5 70.0 71.3 57.8 42.0 40.5 16.7 69.4 68.8 66.9 45.5 49.8 57.5 33.2 70.2 77.4 40.1 28.0 45.9 61.8 24.4 58.3 48.7 65.4 68.4 34.2 60.3 42.7 71.9 22.6 55.1 17.9 25.4 81.2 58.5 68.3 66.0 126.5 63.0 63.9 101.0 73.1 54.5 89.9 93.1 85.1 66.6 150.3 87.4 16.9 104.8 109.8 86.7 88.5 60.3 140.2 57.9 12.7 62.5 17.8 51.3 135.3 109.0 19.1 10.8 80.1 97.8 79.3 130.1 85.4 60.2 22.1 29.1 18.1 86.2 77.3 24.0 25.1 50.4 109.6 117.0 14.4 82.7 19.9 81.6 90.3 60.4 68.9 91.1 135.1 76.3 53.7 91.1 30.2 66.6 155.5 58.1 88.6 70.3 24.0 34.9 14.0 111.8 10.4 82.3 12.3 22.8 33.2 14.9 27.0 17.0 24.3 17.9 18.0 21.0 25.6 21.4 20.9 33.8 21.1 21.4 29.2 12.8 16.7 68.6 68.2 67.3 76.3 70.0 71.3 69.4 68.8 70.2 68.4 71.9 68.3 19.9 25.6 27.1 10.1 9.5 30.1 87.3 84.2 33.0 22.7 41.3 47.9 19.6 35.8 42.1 44.1 4.2 97.0 9.1 24.7 39.2 74.5 6.6 23.8 26.6 28.5 30.5 2.1 8.6 109.3 133.4 42.6 23.9 20.4 7.6 31.5 28.9 22.5 30.3 20.2 10.7 36.7 50.8 15.1 20.6 8.0 46.9 12.3 46.2 6.5 18.0 71.4 18.6 13.0 8.4 103.2 48.4 68.4 16.8 96.0 40.9 61.1 29.9 15.4 19.7 27.4 38.7 26.4 43.8 36.5 30.4 76.9 8.4 40.7 34.8 124.7 MAPK11 "p38-2, p38Beta, PRKM11, SAPK2" ENSG00000185386 "Mitogen-activated protein kinase 11" Q15759 22 50263713-50270767 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 70.9" "Cell type enhanced" "Detected in many" "Adipocytes: 29.5;Astrocytes: 16.6;Endothelial cells: 21.1;Excitatory neurons: 15.8;Hepatic stellate cells: 20.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012961, HPA045069" Approved Approved Mitochondria NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Mitochondria "CAB012961: AB_2533144, HPA045069: AB_2679207" "unprognostic (1.11e-1)" "unprognostic (1.28e-1)" "unprognostic (1.49e-2)" "unprognostic (1.92e-1)" "unprognostic (1.18e-2)" "unprognostic (1.64e-3)" "unprognostic (1.02e-1)" "unprognostic (5.84e-2)" "unprognostic (5.89e-2)" "unprognostic (2.46e-1)" "unprognostic (4.96e-3)" "unprognostic (2.18e-1)" "prognostic unfavorable (6.02e-6)" "unprognostic (9.84e-2)" "unprognostic (4.25e-2)" "unprognostic (9.16e-2)" "unprognostic (2.10e-2)" 27.5 6.8 52.3 7.9 56.0 1.1 24.0 48.2 70.9 15.1 40.6 7.3 1.9 15.5 5.8 9.4 16.7 8.7 18.9 55.2 49.6 18.6 4.8 16.8 9.4 48.2 47.2 12.5 5.7 5.4 28.4 8.3 48.2 18.2 2.6 8.6 7.2 7.2 6.4 7.5 8.3 9.4 47.4 16.3 10.9 6.1 50.2 3.5 11.0 5.8 6.1 11.6 12.3 51.0 2.8 6.8 7.4 27.8 9.5 14.3 0.2 10.2 7.4 6.8 2.7 2.8 5.2 0.0 8.7 9.9 11.3 6.9 4.9 4.2 0.5 13.9 3.4 10.1 10.4 0.6 10.9 2.5 15.0 19.9 12.3 1.9 0.8 7.7 15.2 10.6 8.1 26.8 6.9 12.4 0.5 9.4 0.6 8.4 7.7 26.7 0.1 9.9 10.3 0.0 6.8 18.4 9.0 3.7 7.7 0.9 12.2 7.9 24.0 20.4 16.5 1.5 3.7 1.2 3.2 11.8 10.4 2.9 17.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 52.3 56.0 48.2 70.9 55.2 49.6 48.2 47.2 48.2 47.4 50.2 51.0 29.5 0.0 1.1 16.6 2.2 1.9 1.8 3.2 8.0 3.3 1.1 1.5 6.6 1.5 1.7 0.0 6.2 0.0 1.8 0.1 1.9 1.0 4.7 0.6 1.8 21.1 0.0 0.4 15.8 0.2 0.4 2.7 0.5 1.7 0.0 0.1 20.0 2.1 0.3 0.0 3.6 0.2 2.0 1.3 2.1 9.7 3.1 0.5 5.4 13.1 0.1 5.9 0.0 1.0 0.9 0.7 0.0 2.2 1.6 2.9 0.0 1.9 1.3 11.4 0.0 0.6 1.8 1.3 3.2 1.8 1.3 0.0 3.3 0.7 0.1 1.1 MBLAC2 "DKFZp686P15118, MGC46734" ENSG00000176055 "Metallo-beta-lactamase domain containing 2" Q68D91 5 90458209-90474771 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037757, HPA037758" Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 68: Epididymis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria Nucleoplasm "HPA037757: AB_10670528, HPA037758: " "unprognostic (6.32e-2)" "unprognostic (2.48e-1)" "unprognostic (9.22e-3)" "unprognostic (1.21e-2)" "unprognostic (9.27e-2)" "unprognostic (1.96e-3)" "unprognostic (9.98e-3)" "unprognostic (1.82e-2)" "unprognostic (3.33e-2)" "unprognostic (4.00e-3)" "unprognostic (4.16e-2)" "unprognostic (1.95e-1)" "unprognostic (1.83e-2)" "unprognostic (1.44e-1)" "unprognostic (3.34e-1)" "unprognostic (6.31e-2)" "unprognostic (1.63e-2)" 2.6 3.8 4.3 3.3 4.4 1.5 5.2 4.7 5.9 4.4 1.2 3.1 3.3 5.1 3.3 3.8 3.8 2.4 2.8 4.6 4.8 5.0 6.3 2.3 4.2 3.0 5.1 8.6 3.1 8.1 2.4 2.9 3.5 4.5 3.2 3.4 4.6 3.9 2.3 5.2 3.0 3.7 3.3 3.8 2.6 3.1 6.4 4.3 5.2 2.2 3.9 2.5 2.9 4.7 6.4 2.7 4.6 5.9 6.0 8.0 5.6 5.0 4.5 4.2 4.4 2.1 4.7 14.9 2.9 4.4 5.8 6.4 6.0 7.5 6.6 8.5 4.1 6.7 4.6 4.8 6.3 6.7 2.8 7.0 9.9 3.0 11.6 4.9 5.4 7.9 10.2 8.0 7.2 3.9 6.5 9.1 3.0 1.3 13.1 6.9 7.7 20.5 6.3 2.3 7.9 9.3 4.5 6.5 12.1 2.7 5.4 4.9 6.7 5.2 3.6 6.4 6.5 5.6 6.8 6.5 4.5 13.8 7.2 0.0 0.7 0.5 1.4 1.8 1.6 1.3 1.5 1.5 1.3 2.4 2.0 1.6 0.0 1.6 0.9 0.4 0.6 1.1 4.3 4.4 4.7 5.9 4.6 4.8 3.0 5.1 3.5 3.3 6.4 4.7 3.8 3.2 3.6 2.9 4.7 2.7 1.2 2.8 8.6 8.1 4.6 5.0 4.9 2.8 1.7 1.8 8.4 3.9 3.9 1.9 1.9 1.6 0.3 2.0 5.0 4.2 4.2 6.3 14.4 1.3 3.1 3.5 3.1 2.0 0.0 5.3 3.6 5.8 2.6 3.3 16.4 2.9 4.1 5.1 1.0 0.6 4.1 2.1 1.8 6.5 2.1 5.5 3.1 8.5 15.6 1.8 1.8 5.3 2.1 1.2 3.0 5.5 2.4 6.7 0.0 4.3 4.9 2.5 6.1 7.3 3.3 0.8 3.7 12.6 3.9 0.7 MBTPS2 "KFSD, S2P" ENSG00000012174 "Membrane bound transcription factor peptidase, site 2" O43462 X 21839617-21885423 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Hydrolase, Metalloprotease, Protease" "Disease variant, Ichthyosis, Osteogenesis imperfecta, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005494, CAB009486" Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Mitochondria, Cytosol" "CAB009486: AB_2140370, HPA005494: AB_1079329" "unprognostic (7.97e-3)" "unprognostic (9.12e-2)" "unprognostic (5.38e-2)" "unprognostic (1.18e-2)" "unprognostic (2.65e-1)" "unprognostic (1.50e-1)" "unprognostic (1.85e-1)" "unprognostic (7.22e-2)" "unprognostic (3.32e-1)" "unprognostic (9.30e-2)" "unprognostic (1.99e-1)" "unprognostic (1.77e-1)" "unprognostic (8.38e-2)" "unprognostic (7.76e-2)" "unprognostic (1.07e-1)" "unprognostic (3.61e-1)" "unprognostic (3.05e-2)" 8.6 10.6 3.5 5.2 4.0 1.7 8.8 7.8 4.9 7.5 4.5 5.1 5.2 9.7 6.0 5.8 7.3 6.7 7.7 3.7 4.1 9.4 18.7 5.5 5.0 4.4 4.1 12.5 7.3 11.0 3.8 11.6 4.9 10.5 6.0 8.8 6.6 8.5 7.1 3.7 4.2 10.1 4.1 4.8 5.8 4.1 4.2 4.9 9.0 9.1 4.7 6.8 4.0 6.1 16.9 34.5 16.1 16.5 19.8 24.4 7.7 24.4 24.7 22.7 19.7 13.8 22.5 14.6 12.4 26.2 44.4 15.4 22.4 14.0 27.9 10.9 17.8 7.2 19.7 11.4 27.1 15.6 6.8 23.2 14.8 34.3 25.1 23.0 17.8 8.4 20.3 15.8 26.1 10.5 6.4 8.1 15.0 8.8 25.1 7.9 29.8 16.4 15.7 8.4 3.9 32.8 34.3 21.5 30.5 21.3 28.9 13.2 21.2 28.4 6.6 41.9 18.5 19.1 26.0 6.9 31.6 6.4 28.0 0.0 2.2 0.8 2.2 2.5 2.0 1.9 1.6 2.0 3.6 1.7 2.2 2.6 0.2 2.6 2.6 2.4 3.2 1.7 3.5 4.0 7.8 4.9 3.7 4.1 4.4 4.1 4.9 4.1 4.2 6.1 5.5 9.6 11.5 16.6 5.8 5.5 4.8 7.0 8.0 11.8 7.5 5.1 13.3 8.6 7.1 7.3 18.8 7.0 2.2 3.8 0.0 5.9 0.3 4.0 11.5 5.6 2.4 2.1 16.8 8.9 7.1 10.8 6.1 3.7 10.8 14.5 7.5 18.7 9.4 30.3 25.0 3.4 12.2 9.2 4.0 1.9 10.5 4.8 10.6 11.2 5.0 7.3 3.1 21.6 22.2 6.1 2.4 13.2 9.1 7.4 4.9 7.2 10.7 14.5 0.0 8.6 8.3 2.7 1.5 6.5 2.7 4.8 5.1 12.3 4.3 4.9 MCUB "CCDC109B, FLJ20647" ENSG00000005059 "Mitochondrial calcium uniporter dominant negative subunit beta" Q9NWR8 4 109560209-109688719 "Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 32.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 127.7;Exocrine glandular cells: 111.4;Extravillous trophoblasts: 91.9;Hofbauer cells: 106.8;Pancreatic endocrine cells: 67.9;Syncytiotrophoblasts: 73.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 93.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA048776 Enhanced Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 30: Non-specific - Translation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Vesicles, Mitochondria" "HPA048776: AB_2680518" "unprognostic (6.12e-3)" "unprognostic (1.70e-2)" "unprognostic (3.12e-2)" "unprognostic (1.60e-1)" "unprognostic (1.42e-1)" "unprognostic (1.70e-1)" "unprognostic (1.70e-2)" "unprognostic (3.06e-1)" "unprognostic (2.35e-1)" "unprognostic (1.14e-2)" "unprognostic (1.26e-3)" "unprognostic (3.40e-1)" "prognostic unfavorable (7.35e-6)" "unprognostic (2.48e-1)" "unprognostic (5.21e-2)" "unprognostic (1.21e-1)" "unprognostic (1.42e-2)" 10.2 2.0 2.6 18.4 3.0 10.6 7.6 2.1 3.4 7.0 3.5 5.3 3.8 8.8 1.5 6.8 5.8 7.8 10.5 2.7 4.6 3.5 2.2 7.2 32.2 4.3 3.0 5.6 1.5 1.2 3.7 6.1 3.2 3.0 6.3 3.7 4.9 2.1 1.4 6.2 7.8 8.2 3.7 13.5 4.6 3.0 5.2 31.4 3.3 3.5 25.7 9.2 7.5 4.6 26.9 11.7 6.4 32.6 6.9 18.1 23.9 23.3 14.2 24.9 22.1 0.6 21.6 93.0 4.6 20.2 13.8 7.6 24.1 14.0 21.9 59.2 18.4 11.3 11.6 1.6 12.1 23.6 0.4 11.7 3.8 15.1 13.0 17.7 33.9 35.0 3.3 59.4 19.2 34.0 54.1 0.4 28.2 4.8 15.6 20.4 47.7 10.8 29.6 12.1 25.6 11.1 24.2 73.4 7.7 5.3 9.2 1.2 23.9 9.8 12.6 51.8 40.2 22.3 16.4 22.7 29.9 4.9 6.9 0.4 51.4 0.8 18.9 32.2 26.6 43.6 79.1 56.5 49.8 50.7 114.7 66.2 3.6 65.0 24.4 35.1 74.9 92.2 2.6 3.0 2.1 3.4 2.7 4.6 4.3 3.0 3.2 3.7 5.2 4.6 21.5 9.6 5.2 0.0 19.5 0.0 0.0 0.0 0.0 0.0 12.7 9.9 0.0 0.0 2.5 5.5 0.0 127.7 36.0 0.0 0.0 25.2 0.0 7.0 5.9 11.7 0.0 0.0 0.0 111.4 91.9 15.1 0.0 8.9 1.3 9.1 0.0 0.0 106.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.1 0.0 0.0 14.5 0.0 0.0 0.0 0.0 67.9 0.0 0.0 5.8 0.0 0.0 0.9 2.2 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 73.5 28.2 7.4 0.0 0.0 METTL27 WBSCR27 ENSG00000165171 "Methyltransferase like 27" Q8N6F8 7 73834590-73842516 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Collecting duct cells: 20.2;Distal tubular cells: 29.4;Ductal cells: 16.5;Endometrial ciliated cells: 66.7;Proximal tubular cells: 68.8;Respiratory ciliated cells: 30.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 6.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 18.7;RPMI-8226: 82.2;T-47d: 23.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA074662 Approved Approved Mitochondria,Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Mitochondria, Cytosol" "HPA074662: " "unprognostic (6.70e-2)" "unprognostic (1.98e-1)" "prognostic unfavorable (1.73e-4)" "unprognostic (1.38e-2)" "unprognostic (2.66e-2)" "unprognostic (4.39e-2)" "unprognostic (4.81e-3)" "unprognostic (1.20e-1)" "unprognostic (3.23e-1)" "unprognostic (2.27e-1)" "unprognostic (4.98e-2)" "unprognostic (1.33e-1)" "prognostic favorable (1.10e-6)" "unprognostic (1.86e-1)" "unprognostic (2.15e-2)" "unprognostic (6.49e-2)" "unprognostic (1.24e-2)" 2.6 1.5 1.8 0.4 1.4 0.2 2.9 3.4 2.2 6.4 7.9 2.9 1.9 4.1 1.1 1.6 7.2 2.0 0.7 1.6 1.5 10.7 2.0 2.6 1.2 2.3 3.0 2.7 8.9 6.7 3.1 2.0 2.0 5.2 0.7 0.4 5.1 3.3 0.6 1.8 2.6 0.7 1.7 3.1 1.5 5.2 1.5 1.0 3.9 0.1 0.3 2.5 2.8 1.5 12.8 15.5 0.1 1.2 2.3 6.6 2.5 0.1 0.2 0.5 0.4 0.8 18.7 3.1 2.8 2.6 10.7 1.2 0.0 5.0 0.2 2.1 0.1 0.1 4.7 4.8 2.6 0.0 0.1 2.6 1.1 7.8 3.8 0.8 2.9 1.0 0.3 2.6 1.8 3.6 0.1 0.0 0.3 10.2 4.0 0.9 3.4 82.2 4.1 2.4 1.3 0.5 1.7 1.3 1.4 3.5 23.0 0.7 3.4 4.9 1.2 9.4 5.1 3.5 1.3 0.0 1.0 0.1 1.5 0.0 0.6 1.3 0.0 2.2 0.0 2.1 0.3 0.0 0.9 0.6 0.7 0.5 0.6 0.0 0.5 0.7 6.3 0.2 1.8 1.4 3.4 2.2 1.6 1.5 2.3 3.0 2.0 1.7 1.5 1.5 3.8 6.4 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 6.3 0.0 0.0 2.5 20.2 0.0 5.4 0.5 0.0 29.4 16.5 0.0 66.7 5.2 1.2 0.0 0.0 0.0 2.3 2.2 2.2 0.0 6.1 2.5 0.7 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 68.8 30.6 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 3.4 0.9 0.2 0.0 0.0 METTL4 "FLJ23017, HsT661" ENSG00000101574 "Methyltransferase like 4" Q8N3J2 18 2537525-2571509 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Chromatin regulator, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040061, HPA046734" Approved Approved Mitochondria NA Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 16: Immune cells - Immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA040061: AB_10697713, HPA046734: AB_2732532" "unprognostic (1.85e-2)" "unprognostic (1.27e-1)" "unprognostic (7.31e-2)" "unprognostic (1.07e-1)" "unprognostic (1.11e-1)" "unprognostic (5.06e-3)" "unprognostic (1.12e-5)" "unprognostic (1.74e-1)" "unprognostic (5.12e-2)" "unprognostic (2.23e-2)" "unprognostic (2.24e-1)" "unprognostic (1.89e-1)" "unprognostic (7.72e-2)" "unprognostic (3.26e-1)" "unprognostic (4.00e-1)" "unprognostic (2.96e-2)" "unprognostic (1.05e-3)" 7.4 4.9 5.2 7.9 6.0 5.5 5.8 5.7 7.0 8.4 5.6 5.9 5.7 7.5 5.4 6.1 6.2 5.7 5.6 4.9 5.7 6.4 5.0 6.2 11.5 6.3 5.6 6.8 4.4 6.4 5.2 5.9 6.5 6.6 6.7 5.1 5.5 7.1 3.4 5.9 7.9 6.7 6.1 10.4 5.8 7.3 5.6 10.4 8.9 5.5 11.0 6.8 7.8 7.6 12.7 5.0 15.1 8.3 5.9 8.7 19.0 19.9 15.7 18.2 16.9 10.8 9.2 24.3 11.5 8.3 16.4 10.7 24.7 9.3 21.2 18.6 9.1 10.6 10.5 7.9 9.0 23.1 12.0 7.1 19.3 19.6 12.0 10.3 17.8 15.9 14.0 33.8 14.3 5.7 16.0 7.4 9.2 10.5 8.2 12.5 13.6 16.7 8.9 7.0 27.6 12.8 16.2 9.3 18.6 11.6 10.8 14.8 11.1 21.9 28.9 19.4 26.3 16.1 47.6 15.7 14.1 15.5 23.8 18.6 2.7 7.3 6.1 2.6 7.0 6.2 7.0 8.5 1.9 7.3 8.5 7.9 10.0 5.9 2.2 3.8 8.8 4.9 5.2 6.0 5.7 7.0 4.9 5.7 6.3 5.6 6.5 6.1 5.6 7.6 24.3 12.8 8.2 8.5 21.1 4.8 13.6 6.5 10.8 9.6 7.6 7.4 3.8 10.0 10.3 3.7 14.6 7.5 13.7 10.1 0.0 5.9 6.9 7.5 9.1 10.0 2.4 11.0 17.0 7.3 9.4 7.3 12.2 7.4 7.0 10.3 11.4 4.9 6.0 8.4 20.3 7.6 4.1 7.0 6.5 3.3 12.8 7.0 3.6 14.0 4.5 6.6 13.4 18.1 25.8 8.3 4.0 10.9 15.0 10.8 10.1 5.1 12.0 6.5 13.1 8.3 6.8 30.5 21.8 9.0 4.8 10.4 18.3 8.5 6.2 19.4 MGST1 "GST12, MGST-I" ENSG00000008394 "Microsomal glutathione S-transferase 1" P10620 12 16347142-16609259 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1096.9;adrenal gland: 1137.3;liver: 3104.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 1205.9;Club cells: 1308.7;Hepatocytes: 4345.6;Proximal tubular cells: 1265.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 170.2;myeloid DC: 123.5" "Group enriched" "Detected in many" 13 "dendritic cells: 123.5;monocytes: 170.2" "Cell line enhanced" "Detected in many" "ASC diff: 5391.4;ASC TERT1: 2078.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044840 Enhanced Approved "Endoplasmic reticulum,Mitochondria" NA NA 19000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Mitochondria "Endoplasmic reticulum" "HPA044840: AB_10965550" "unprognostic (4.57e-2)" "unprognostic (4.80e-3)" "unprognostic (5.82e-2)" "unprognostic (2.92e-3)" "unprognostic (3.97e-3)" "unprognostic (1.03e-1)" "unprognostic (8.19e-2)" "unprognostic (1.03e-1)" "unprognostic (4.82e-2)" "unprognostic (3.42e-1)" "unprognostic (1.37e-3)" "unprognostic (2.20e-1)" "prognostic unfavorable (7.45e-4)" "unprognostic (9.90e-2)" "unprognostic (4.61e-1)" "prognostic favorable (1.97e-4)" "unprognostic (4.19e-1)" 1096.9 1137.3 139.2 76.1 143.9 79.3 574.8 131.4 200.7 69.7 111.9 315.5 128.9 32.7 43.9 195.3 78.4 200.8 135.1 133.9 165.4 392.9 3104.7 177.2 3.5 156.5 155.7 11.4 131.3 0.8 52.6 14.2 166.6 161.2 212.8 7.0 155.3 55.8 25.5 88.8 119.5 44.7 146.4 7.3 131.4 20.2 147.5 14.0 272.3 43.3 7.7 267.9 114.7 132.9 1.4 495.2 115.6 139.4 5391.4 2078.4 1.5 408.5 418.5 220.6 339.1 186.0 838.6 0.4 48.5 535.8 694.2 2.4 317.0 663.5 202.9 1.1 41.4 175.7 256.6 664.8 1252.0 350.4 1.2 1375.9 714.7 671.2 710.5 540.4 393.1 0.1 126.7 0.6 486.3 101.2 0.3 137.0 987.6 0.7 391.2 0.4 69.3 229.3 503.3 982.1 21.8 17.1 645.8 411.8 17.5 630.1 442.5 190.8 248.0 226.1 30.5 447.3 541.1 0.6 1.7 1.5 748.1 538.5 7.1 11.3 170.2 1.8 0.1 26.3 0.5 1.0 0.2 0.1 123.5 0.0 0.1 0.1 5.9 0.2 5.9 34.1 1.1 55.9 139.2 143.9 131.4 200.7 133.9 165.4 156.5 155.7 166.6 146.4 147.5 132.9 39.6 266.0 651.3 130.2 14.0 25.6 130.2 1205.9 91.0 0.0 383.8 262.6 5.1 574.7 1308.7 71.7 0.0 2.9 9.8 288.1 181.9 26.9 25.4 299.9 198.2 19.6 45.6 92.8 4.4 434.1 218.1 404.5 153.9 947.9 34.1 26.3 67.5 4345.6 160.2 0.0 0.5 280.5 740.6 176.4 52.0 17.9 33.2 75.7 39.2 6.5 224.4 1.0 5.2 1.0 0.8 322.7 175.0 113.2 6.0 467.2 209.5 1265.6 526.1 1.3 0.0 11.3 124.3 0.7 2.3 510.3 17.6 7.9 22.1 152.4 534.1 883.3 MMAB "cblB, CFAP23" ENSG00000139428 "Metabolism of cobalamin associated B" Q96EY8 12 109553715-109573580 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 103.6" "Cell type enhanced" "Detected in all" "Hepatocytes: 225.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039017 Supported Approved Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 15: Hepatocytes - Hemostasis" Mitochondria "HPA039017: AB_10673603" "unprognostic (1.16e-1)" "unprognostic (1.25e-2)" "unprognostic (1.90e-1)" "unprognostic (1.79e-1)" "unprognostic (4.38e-2)" "unprognostic (2.10e-1)" "unprognostic (1.38e-1)" "unprognostic (4.22e-1)" "unprognostic (2.04e-2)" "unprognostic (5.15e-2)" "unprognostic (1.47e-3)" "unprognostic (2.58e-1)" "prognostic favorable (1.55e-4)" "unprognostic (4.90e-2)" "unprognostic (1.51e-1)" "unprognostic (2.23e-1)" "unprognostic (9.65e-2)" 15.5 51.2 17.8 6.3 18.3 5.8 15.8 18.8 26.9 12.4 18.6 15.8 13.0 10.7 21.2 29.1 13.0 6.0 30.0 17.0 18.8 32.8 103.6 14.9 6.2 22.2 19.0 18.9 23.0 9.8 20.5 4.9 21.3 26.5 7.9 7.3 17.1 6.3 21.1 18.2 14.0 5.6 19.0 12.4 17.7 12.6 18.9 5.5 22.1 16.2 6.5 14.1 14.7 22.9 32.2 22.3 22.2 17.6 8.8 17.7 11.3 7.1 16.2 10.3 10.8 25.8 29.5 21.0 19.9 8.0 19.1 32.9 14.6 54.9 4.6 8.2 60.9 8.6 15.9 42.1 31.3 18.4 7.2 24.0 33.5 22.2 9.7 12.3 9.7 16.4 27.5 15.5 7.3 74.7 16.6 29.2 27.3 3.3 31.6 13.6 8.7 53.9 45.3 30.3 34.1 14.8 15.8 29.2 12.7 6.2 60.5 50.5 5.4 8.6 3.6 6.1 10.4 11.9 9.6 24.0 19.0 22.2 23.9 7.4 7.2 1.0 15.3 10.0 12.2 13.6 11.1 12.1 11.3 17.8 15.2 14.6 1.9 11.2 10.9 9.2 5.8 10.3 17.8 18.3 18.8 26.9 17.0 18.8 22.2 19.0 21.3 19.0 18.9 22.9 25.1 35.3 80.8 9.8 20.4 10.3 33.1 105.6 17.1 32.9 59.6 47.0 52.3 60.1 68.9 42.3 29.2 55.4 15.2 33.6 150.6 49.7 41.3 23.8 10.0 22.1 33.0 34.1 6.4 71.3 37.6 24.7 28.5 16.5 16.5 34.3 28.5 225.3 34.8 104.3 8.5 50.4 71.2 20.4 10.2 82.9 40.4 13.5 26.6 4.7 25.1 30.6 30.9 6.6 21.5 29.7 30.0 30.5 18.1 31.8 61.9 143.6 62.1 29.7 13.1 17.9 26.3 26.0 15.8 44.7 19.7 61.8 16.1 121.1 56.6 30.3 MMUT "MCM, MUT" ENSG00000146085 "Methylmalonyl-CoA mutase" P22033 6 49430360-49463253 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Isomerase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 199.0" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 62.5;Cytotrophoblasts: 26.5;Extravillous trophoblasts: 13.3;Hofbauer cells: 12.4;Syncytiotrophoblasts: 33.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035971, HPA035972" Enhanced Approved Mitochondria,Cytosol NA NA 150000 "Cluster 27: Non-specific - Gene expression" "Cluster 85: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Cytosol Mitochondria "HPA035971: AB_10696648, HPA035972: AB_2674895" "unprognostic (1.34e-2)" "unprognostic (1.12e-1)" "unprognostic (1.17e-2)" "unprognostic (3.72e-2)" "unprognostic (3.18e-3)" "unprognostic (1.20e-1)" "unprognostic (1.16e-2)" "unprognostic (1.16e-2)" "unprognostic (3.62e-2)" "unprognostic (1.89e-2)" "unprognostic (6.57e-2)" "unprognostic (9.89e-2)" "prognostic favorable (8.71e-13)" "unprognostic (5.38e-2)" "unprognostic (3.78e-1)" "unprognostic (6.01e-3)" "unprognostic (1.91e-1)" 19.8 23.3 12.1 11.5 13.2 8.6 18.4 14.2 16.2 14.0 19.3 22.6 27.1 15.2 15.6 17.9 13.9 14.2 31.0 12.1 13.5 50.6 199.0 12.5 11.8 13.0 12.7 24.2 24.6 31.1 11.7 13.2 13.2 20.8 21.5 17.2 18.7 15.8 23.6 15.0 20.1 14.9 14.1 9.4 20.1 14.6 13.3 12.2 19.2 36.1 11.2 13.0 11.9 16.3 23.9 8.3 24.6 28.8 47.8 45.1 13.6 20.9 27.3 21.6 31.7 9.7 12.1 21.9 16.3 22.4 32.6 13.3 27.6 14.8 30.2 18.9 20.0 11.7 17.5 25.4 34.8 15.1 10.8 27.4 21.6 22.0 25.4 19.3 21.1 23.4 21.6 25.6 25.7 15.0 17.9 14.9 10.5 25.0 6.0 15.8 30.8 30.7 24.9 22.6 22.7 15.8 23.0 16.3 35.7 25.6 14.2 23.9 15.4 20.0 14.6 27.4 28.7 10.0 12.2 18.8 28.1 17.6 17.9 16.0 6.5 11.4 6.4 8.8 8.2 7.6 7.7 8.1 7.8 6.9 9.6 7.2 3.8 12.5 14.7 5.5 10.9 5.8 12.1 13.2 14.2 16.2 12.1 13.5 13.0 12.7 13.2 14.1 13.3 16.3 6.6 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 62.5 0.0 0.0 0.0 0.0 26.5 2.2 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 13.3 5.3 0.0 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 33.4 0.6 0.0 0.0 0.0 MOCOS "FLJ20733, HMCS, MOS" ENSG00000075643 "Molybdenum cofactor sulfurase" Q96EN8 18 36187497-36272157 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 10.3;liver: 16.0" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 18.8;Hepatocytes: 39.4;Proximal enterocytes: 22.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTCEpi: 40.7;hTERT-HME1: 49.7;SiHa: 54.9;SK-MEL-30: 38.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039412, HPA047958" Uncertain Supported Mitochondria,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 2: Hepatocytes - Metabolism" Mitochondria Cytosol "HPA039412: AB_2676496, HPA047958: AB_2680225" "unprognostic (3.07e-3)" "unprognostic (1.81e-1)" "unprognostic (1.69e-2)" "unprognostic (1.50e-1)" "unprognostic (3.18e-3)" "unprognostic (2.55e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (3.55e-4)" "unprognostic (5.84e-2)" "unprognostic (1.33e-1)" "prognostic unfavorable (1.29e-4)" "unprognostic (2.91e-2)" "prognostic unfavorable (3.03e-12)" "unprognostic (8.98e-2)" "unprognostic (2.37e-1)" "unprognostic (4.09e-1)" "unprognostic (6.35e-2)" 2.0 10.3 0.3 0.9 0.3 0.3 2.5 0.5 0.5 0.9 0.5 1.6 6.1 0.8 1.9 3.8 1.7 1.4 0.3 0.4 0.4 1.2 16.0 1.6 0.2 1.2 0.3 6.4 0.8 2.3 2.0 1.0 1.3 1.3 1.6 0.7 1.8 3.3 0.6 2.0 6.4 0.6 0.2 0.3 1.6 0.9 0.6 0.1 1.2 0.4 1.2 2.7 0.7 0.3 14.3 4.8 0.2 0.1 4.3 5.5 2.9 8.2 4.6 3.9 10.0 3.1 4.4 0.1 2.5 13.4 1.0 8.6 2.9 12.9 5.4 2.4 2.3 0.2 13.5 11.8 14.6 0.1 3.8 8.7 40.7 15.2 49.7 0.5 0.6 0.1 4.9 0.1 6.2 3.6 0.0 0.1 0.8 3.4 4.1 0.0 0.1 0.0 5.5 18.5 0.1 1.2 54.9 3.3 38.8 0.9 2.5 0.2 2.7 3.0 3.7 6.7 1.4 0.1 0.1 0.1 7.8 0.1 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.3 0.5 0.5 0.4 0.4 1.2 0.3 1.3 0.2 0.6 0.3 0.9 12.8 5.0 0.3 0.9 0.6 1.4 3.7 1.8 0.3 4.5 1.9 1.0 4.3 6.4 0.0 2.1 0.5 0.2 2.2 0.0 3.1 7.2 5.9 3.4 0.8 3.0 0.0 0.9 12.4 4.3 2.4 1.5 18.8 0.0 2.0 0.4 39.4 0.6 0.0 1.1 3.1 6.1 0.6 2.6 3.2 1.8 1.0 3.6 4.7 11.9 6.6 0.0 1.0 0.3 4.6 2.3 9.1 0.9 2.3 22.4 0.2 4.5 0.5 0.0 6.5 1.2 0.1 0.3 5.1 1.3 2.3 0.5 2.7 4.5 2.2 MORN1 FLJ13941 ENSG00000116151 "MORN repeat containing 1" Q5T089 1 2321253-2391707 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 25.4;Endometrial ciliated cells: 38.1;Late spermatids: 25.1;Respiratory ciliated cells: 36.7;Spermatocytes: 25.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HeLa: 16.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA005858, HPA070703" Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 20: HeLa - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Mitochondria" "HPA005858: AB_1848709, HPA070703: AB_2686299" "unprognostic (1.39e-3)" "unprognostic (6.49e-2)" "unprognostic (1.58e-1)" "unprognostic (8.21e-3)" "unprognostic (9.12e-2)" "unprognostic (5.87e-3)" "unprognostic (1.87e-1)" "unprognostic (2.65e-1)" "unprognostic (3.61e-2)" "unprognostic (5.97e-2)" "unprognostic (1.11e-2)" "unprognostic (2.60e-1)" "unprognostic (8.88e-3)" "unprognostic (2.53e-1)" "unprognostic (6.29e-2)" "unprognostic (1.09e-1)" "unprognostic (1.70e-1)" 2.5 2.7 2.5 1.5 3.2 1.0 4.2 14.3 4.7 7.1 8.2 3.7 1.9 5.3 4.4 3.1 15.7 2.3 1.9 2.6 2.4 6.4 3.2 3.8 1.5 4.6 5.7 9.8 4.0 2.7 10.0 0.9 2.5 6.0 1.1 3.9 4.4 3.2 2.3 2.9 2.6 1.1 3.2 2.2 2.8 14.8 3.1 2.0 13.5 1.0 1.4 3.0 4.0 2.1 6.4 7.6 5.2 4.8 1.7 0.8 5.4 1.9 1.3 3.0 2.5 3.6 7.0 1.7 4.0 1.2 2.2 7.7 1.1 3.0 2.9 3.9 8.0 1.6 16.4 4.0 1.5 2.1 0.9 1.0 0.6 2.8 2.5 2.3 2.1 3.2 2.7 1.9 1.1 8.9 2.1 0.7 3.1 3.3 6.5 2.2 4.7 2.7 2.3 2.8 8.6 4.2 5.0 8.9 4.1 2.3 4.8 0.6 0.7 3.4 5.0 2.5 2.2 4.5 1.8 1.1 6.9 1.2 2.4 0.0 0.3 0.1 0.5 0.1 0.3 0.4 0.6 0.4 0.4 0.8 0.9 0.4 1.7 0.3 2.0 1.5 0.0 0.4 2.5 3.2 14.3 4.7 2.6 2.4 4.6 5.7 2.5 3.2 3.1 2.1 1.7 3.2 3.2 9.8 3.7 1.7 4.1 4.6 1.8 8.9 5.3 5.2 3.3 4.3 3.9 14.7 20.9 3.6 1.0 2.1 3.9 2.2 25.4 38.1 4.4 1.4 5.4 4.8 17.7 1.4 1.8 2.5 5.6 4.3 5.7 3.4 1.1 1.8 2.9 10.1 10.7 0.9 6.1 0.6 0.7 25.1 2.5 1.0 1.8 4.7 1.2 7.1 4.1 3.5 2.9 1.3 0.6 3.0 2.1 2.0 2.3 9.7 36.7 21.5 0.0 5.7 3.6 25.3 6.4 2.5 2.3 1.9 2.0 2.8 2.2 3.2 MPP2 "DKFZp761D0712, DLG2" ENSG00000108852 "Membrane palmitoylated protein 2" Q14168 17 43875357-43909711 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 91.0;Early spermatids: 69.6;Horizontal cells: 35.3;Oligodendrocytes: 59.6;Spermatogonia: 31.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "T-47d: 24.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026486, HPA073483" Enhanced Approved Mitochondria,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 56: Bipolar cells - Visual perception" "Mitochondria, Cytosol" "HPA026486: AB_1854085, HPA073483: " "unprognostic (1.18e-1)" "unprognostic (1.68e-1)" "unprognostic (1.30e-5)" "prognostic unfavorable (1.87e-4)" "unprognostic (4.37e-2)" "unprognostic (2.86e-2)" "unprognostic (7.95e-3)" "unprognostic (2.34e-1)" "unprognostic (1.25e-1)" "unprognostic (3.69e-2)" "unprognostic (3.03e-3)" "unprognostic (2.11e-1)" "unprognostic (2.72e-2)" "unprognostic (4.93e-2)" "unprognostic (1.85e-1)" "unprognostic (7.23e-2)" "unprognostic (6.89e-4)" 2.5 3.8 22.2 1.3 25.7 0.5 3.3 25.0 27.0 5.3 7.3 9.4 1.1 5.6 26.0 3.0 5.0 2.2 8.9 23.3 24.2 1.6 0.2 1.4 0.5 30.0 27.1 3.2 3.4 15.8 13.7 2.5 26.5 7.5 1.2 15.7 1.4 8.7 1.0 1.8 2.5 5.0 24.7 0.7 3.7 16.9 28.0 0.7 3.5 1.5 0.6 6.7 4.4 41.6 7.2 10.5 11.0 15.7 1.4 1.0 6.0 2.5 0.3 9.9 9.0 3.7 4.7 10.4 5.7 2.5 12.2 2.9 15.1 6.0 7.0 0.0 11.5 0.9 9.2 0.2 0.3 0.0 2.9 1.5 0.5 6.8 0.1 5.4 0.7 16.6 3.9 0.0 2.5 2.8 1.5 0.8 19.7 0.8 6.4 7.4 15.5 0.7 0.2 0.2 11.6 10.7 3.0 1.0 4.1 9.8 24.5 4.9 0.1 10.5 13.2 4.0 4.5 3.4 7.4 0.0 15.8 6.9 2.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.1 22.2 25.7 25.0 27.0 23.3 24.2 30.0 27.1 26.5 24.7 28.0 41.6 2.1 0.0 0.0 11.1 0.0 0.4 1.4 1.0 0.0 91.0 0.5 2.9 10.5 0.0 0.0 0.0 2.1 5.8 0.1 0.1 0.0 0.7 69.6 0.1 0.4 1.4 0.0 0.0 20.4 0.4 0.4 2.7 0.0 0.1 0.0 1.2 0.0 0.0 0.7 35.3 19.0 0.0 0.0 0.0 0.4 21.1 3.7 0.2 0.0 1.9 0.0 16.1 0.0 13.6 59.6 0.5 0.0 5.7 0.1 0.0 0.0 0.1 0.0 7.1 0.0 1.5 1.9 23.2 31.4 0.2 0.1 2.7 0.3 0.1 0.0 0.0 MPPED2 "239FB, C11orf8, D11S302E, dJ1024C24.1, dJ873F21.1, FAM1B, Hs.46638" ENSG00000066382 "Metallophosphoesterase domain containing 2" Q15777 11 30384493-30586872 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 24.5;thyroid gland: 24.6" "Cell type enhanced" "Detected in many" "Astrocytes: 155.7;Cone photoreceptor cells: 285.7;Excitatory neurons: 108.1;Horizontal cells: 82.4;Oligodendrocyte precursor cells: 345.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.8" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HaCaT: 21.6;HAP1: 12.2;JURKAT: 10.9;RT4: 9.0;SH-SY5Y: 6.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062575 Approved Nucleoli,Vesicles,Mitochondria NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoli "Vesicles, Mitochondria" "HPA062575: AB_2684797" "unprognostic (9.60e-3)" "unprognostic (6.12e-3)" "unprognostic (3.70e-3)" "unprognostic (4.56e-2)" "unprognostic (5.46e-2)" "unprognostic (5.04e-2)" "unprognostic (1.46e-1)" "unprognostic (2.32e-1)" "unprognostic (1.57e-2)" "unprognostic (1.13e-1)" "unprognostic (7.98e-4)" "unprognostic (6.82e-2)" "unprognostic (2.47e-7)" "unprognostic (3.64e-3)" "unprognostic (2.50e-1)" "unprognostic (2.22e-2)" "unprognostic (2.57e-2)" 2.0 5.2 6.3 0.5 13.3 0.3 4.1 4.7 10.5 24.5 0.9 4.9 0.7 6.4 5.6 0.9 8.9 1.0 3.7 11.9 13.0 9.6 0.4 0.4 0.2 19.6 10.3 0.5 1.6 3.2 11.0 1.6 11.7 12.6 0.6 16.0 10.3 7.4 5.1 0.7 1.0 3.6 4.9 2.3 1.7 1.7 9.5 3.6 24.6 1.5 0.3 3.3 5.1 6.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.6 12.2 0.0 0.0 0.0 2.6 0.0 0.2 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.0 0.9 0.0 0.3 3.5 0.1 0.1 0.0 3.4 0.2 0.0 9.0 0.1 6.5 0.0 0.0 3.6 1.3 1.8 0.0 0.1 0.0 1.0 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 1.8 0.0 0.0 0.2 0.1 0.4 0.5 0.0 0.0 0.7 0.0 0.2 0.0 0.1 6.3 13.3 4.7 10.5 11.9 13.0 19.6 10.3 11.7 4.9 9.5 6.8 3.1 0.0 2.2 155.7 1.8 1.0 51.7 2.6 2.8 26.7 3.6 5.2 5.2 0.0 1.0 46.0 285.7 0.3 0.5 0.1 25.4 4.2 2.1 35.6 1.5 6.3 0.0 1.3 108.1 0.0 0.2 2.6 0.0 13.8 5.1 12.1 0.7 0.2 4.1 82.4 56.0 0.3 2.0 22.5 3.6 1.6 0.3 2.7 5.4 13.1 0.5 44.0 0.0 345.8 7.9 0.1 0.1 3.4 0.5 19.3 0.0 3.1 3.0 18.5 0.0 1.2 7.1 0.1 2.1 1.5 1.1 0.5 0.8 0.4 0.0 28.4 MPST "MST, TST2, TUM1" ENSG00000128309 "Mercaptopyruvate sulfurtransferase" P25325 22 37019635-37029821 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 390.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 553.6;Hepatocytes: 578.6;Paneth cells: 621.4;Proximal enterocytes: 1322.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001240 Enhanced Approved Mitochondria,Cytosol NA NA 2900000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 45: Enterocytes - Digestion" Mitochondria Cytosol "HPA001240: AB_1079408" "unprognostic (7.18e-3)" "unprognostic (4.45e-1)" "unprognostic (1.80e-1)" "unprognostic (1.30e-3)" "unprognostic (1.73e-3)" "unprognostic (1.43e-1)" "unprognostic (7.07e-2)" "unprognostic (2.15e-1)" "unprognostic (2.22e-1)" "unprognostic (1.35e-1)" "unprognostic (2.25e-1)" "unprognostic (1.58e-1)" "unprognostic (3.15e-3)" "unprognostic (3.98e-2)" "unprognostic (3.51e-1)" "unprognostic (2.52e-1)" "prognostic favorable (5.89e-4)" 58.0 57.3 25.3 10.0 32.3 36.5 51.0 29.0 31.0 40.9 29.8 102.4 106.5 34.7 0.6 91.5 42.9 16.6 64.2 22.9 23.4 71.4 390.7 43.5 8.8 34.0 27.5 81.7 106.4 4.8 14.7 9.1 29.7 45.3 17.0 0.5 43.5 9.6 89.7 82.3 93.0 7.0 26.0 22.1 70.3 51.7 31.4 4.5 24.8 23.1 6.0 48.3 62.3 35.1 44.0 50.4 24.2 50.0 27.8 17.2 38.1 23.4 20.6 24.8 33.2 48.6 18.9 68.7 33.0 16.7 16.7 29.9 20.9 33.8 3.6 41.4 119.2 26.5 21.3 115.6 87.5 29.0 35.6 30.0 64.2 16.1 15.1 22.8 50.6 33.1 48.0 19.3 7.0 33.8 2.6 97.5 45.7 56.7 52.2 73.6 28.8 51.9 25.5 14.0 12.4 92.9 15.6 23.9 46.6 12.2 26.0 45.6 39.8 21.3 60.1 23.9 16.0 33.3 16.8 21.0 7.7 34.7 11.1 48.5 71.9 54.7 31.0 27.5 42.4 24.9 20.1 26.4 104.0 25.0 2.7 10.4 21.9 87.8 12.7 16.3 44.3 35.4 25.3 32.3 29.0 31.0 22.9 23.4 34.0 27.5 29.7 26.0 31.4 35.1 21.3 35.3 61.9 14.7 25.1 81.6 80.4 120.3 70.6 4.5 81.4 83.4 29.4 243.1 70.0 60.7 0.0 61.9 20.3 553.6 133.1 146.4 191.1 38.5 46.8 42.6 108.6 122.6 1.1 148.3 119.1 52.8 87.1 72.5 17.2 140.3 108.5 578.6 77.5 3.3 1.9 363.1 85.5 84.6 77.6 115.1 91.0 62.7 58.7 3.7 60.7 24.8 56.7 4.5 14.9 117.9 621.4 84.7 65.7 77.7 1322.1 469.8 13.4 2.8 46.0 34.4 36.0 101.3 11.5 133.7 152.9 50.1 26.6 57.7 397.5 110.6 MRPL1 BM022 ENSG00000169288 "Mitochondrial ribosomal protein L1" Q9BYD6 4 77862830-77952785 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043656 Supported Approved Mitochondria NA NA "Cluster 37: B-cells - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA043656: AB_2678601" "unprognostic (9.03e-3)" "unprognostic (3.25e-1)" "unprognostic (1.11e-3)" "unprognostic (2.88e-1)" "unprognostic (4.52e-2)" "unprognostic (5.29e-3)" "unprognostic (4.69e-3)" "unprognostic (5.44e-2)" "unprognostic (1.66e-2)" "unprognostic (5.14e-3)" "unprognostic (8.79e-2)" "unprognostic (2.22e-2)" "prognostic favorable (3.35e-5)" "unprognostic (7.63e-2)" "unprognostic (1.87e-1)" "unprognostic (7.13e-2)" "unprognostic (9.17e-3)" 19.4 17.7 17.1 17.4 17.7 26.9 24.4 16.8 20.9 16.5 15.7 28.3 19.5 18.6 21.0 20.5 17.0 11.8 41.7 17.9 18.2 38.1 33.8 13.1 23.6 17.3 17.1 19.0 14.1 21.4 8.1 21.4 17.9 16.0 29.4 14.5 19.3 15.0 67.3 14.6 18.6 21.4 17.1 15.0 17.8 8.8 17.8 19.3 17.7 67.6 24.2 19.8 9.2 17.7 40.5 26.2 47.3 40.7 36.6 47.4 41.2 44.6 28.6 57.4 39.3 55.0 71.6 71.4 53.9 37.1 35.8 32.8 71.1 82.5 75.6 47.6 37.6 61.1 27.6 60.4 47.5 126.2 28.3 37.7 76.7 51.2 53.0 37.8 70.4 50.1 90.3 24.1 73.6 46.0 76.0 84.9 52.0 92.0 34.3 90.7 60.6 41.1 113.3 43.2 52.1 25.9 36.1 88.7 84.5 38.0 43.7 61.0 41.9 37.5 54.3 37.7 65.1 21.1 28.1 74.6 31.9 71.8 49.3 9.0 11.5 7.0 20.6 19.0 20.6 27.8 22.2 23.1 22.1 25.5 26.8 29.5 1.7 23.2 16.9 18.0 25.8 15.4 17.1 17.7 16.8 20.9 17.9 18.2 17.3 17.1 17.9 17.1 17.8 17.7 40.1 25.6 35.7 22.5 45.7 12.7 17.1 68.6 13.6 24.6 31.6 37.2 122.1 57.2 33.5 33.1 18.8 72.7 75.5 22.2 135.0 46.0 15.5 33.9 40.9 34.9 47.9 34.9 45.9 36.7 51.9 27.5 18.8 38.5 42.4 38.7 40.7 134.3 47.7 25.2 39.7 60.5 61.1 25.1 12.7 9.3 31.1 23.5 16.0 35.6 34.1 26.7 64.9 45.2 47.7 28.3 24.9 33.4 38.6 14.7 36.0 144.8 20.6 42.4 39.5 31.4 45.9 21.1 48.0 23.1 12.8 34.9 65.8 61.7 70.9 15.5 MRPL21 ENSG00000197345 "Mitochondrial ribosomal protein L21" Q7Z2W9 11 68891276-68903835 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051657 Approved Approved Nucleoplasm,Mitochondria "Intracellular and membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Mitochondria" "HPA051657: AB_2681565" "unprognostic (1.80e-1)" "unprognostic (6.09e-2)" "unprognostic (4.80e-2)" "unprognostic (8.96e-3)" "unprognostic (9.25e-3)" "prognostic unfavorable (5.97e-4)" "unprognostic (3.23e-2)" "unprognostic (1.51e-1)" "unprognostic (1.09e-1)" "unprognostic (1.06e-1)" "unprognostic (4.84e-2)" "unprognostic (7.36e-2)" "unprognostic (1.26e-2)" "unprognostic (3.73e-2)" "unprognostic (1.72e-1)" "unprognostic (4.36e-2)" "unprognostic (3.12e-1)" 43.5 44.4 56.0 34.0 57.3 60.5 52.5 62.8 71.9 45.3 57.7 67.1 38.7 50.4 48.4 58.4 45.2 27.1 120.2 57.6 59.5 68.0 66.1 31.5 43.8 59.5 57.4 48.6 53.6 56.3 44.7 33.1 59.6 44.1 42.5 29.7 99.5 39.1 131.0 50.4 46.0 35.1 56.9 37.0 53.0 47.0 57.9 37.2 44.7 109.1 42.9 49.8 44.9 56.9 105.2 145.6 86.0 82.3 59.1 63.5 101.4 71.8 77.2 132.8 90.4 297.3 132.7 163.5 157.2 78.0 122.0 129.9 143.8 138.6 102.8 109.7 112.6 114.4 102.4 181.0 116.6 201.4 83.4 95.0 69.4 134.1 156.0 64.7 93.7 115.1 229.2 119.4 80.7 196.7 95.5 210.5 78.0 307.6 210.3 135.2 102.9 253.0 134.0 120.8 139.3 111.3 91.1 181.6 302.7 68.7 188.7 115.4 79.3 90.6 90.6 201.3 135.5 88.9 149.5 232.3 120.6 120.4 125.7 79.6 113.0 61.6 72.4 122.8 77.1 162.2 94.5 78.8 124.2 105.8 89.3 74.1 32.1 93.3 114.2 92.0 113.2 114.0 56.0 57.3 62.8 71.9 57.6 59.5 59.5 57.4 59.6 56.9 57.9 56.9 38.9 35.3 38.7 5.5 47.4 50.2 76.8 145.1 68.9 36.3 56.5 65.4 179.8 67.2 82.0 80.9 8.4 122.8 34.6 127.7 299.3 106.7 176.9 72.2 59.8 50.4 61.7 56.0 5.6 105.3 114.8 53.9 42.8 63.0 65.2 31.8 40.7 115.9 110.4 11.8 6.4 115.6 85.5 56.3 41.3 227.3 74.9 47.0 78.2 1.0 69.8 69.0 34.0 2.0 5.1 86.3 93.0 72.2 63.8 79.6 150.6 272.9 72.8 51.4 26.3 59.3 85.8 86.6 60.5 83.2 51.9 81.3 44.2 55.0 141.6 75.0 MRPL22 "HSPC158, MRP-L25, RPML25" ENSG00000082515 "Mitochondrial ribosomal protein L22" Q9NWU5 5 154941073-154969411 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047063 Uncertain Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA047063: AB_2679919" "unprognostic (9.17e-2)" "unprognostic (1.18e-2)" "unprognostic (2.16e-2)" "unprognostic (2.56e-2)" "unprognostic (5.42e-2)" "unprognostic (6.65e-2)" "unprognostic (1.80e-2)" "unprognostic (4.86e-2)" "unprognostic (2.03e-1)" "unprognostic (3.01e-3)" "unprognostic (3.40e-1)" "unprognostic (1.14e-1)" "unprognostic (1.77e-1)" "unprognostic (3.54e-1)" "unprognostic (2.69e-1)" "unprognostic (4.09e-2)" "unprognostic (4.29e-2)" 23.9 38.4 18.4 20.3 18.4 40.9 26.3 20.0 27.9 20.7 17.7 28.4 26.1 20.5 26.0 30.8 18.9 15.4 46.3 18.5 19.0 37.5 49.3 19.6 28.5 19.5 18.8 18.1 30.3 31.2 23.8 24.2 19.7 19.4 28.0 17.0 24.8 19.3 38.5 23.6 22.9 20.0 18.7 26.2 27.1 29.4 18.8 28.2 23.3 34.5 27.1 24.6 21.6 19.6 68.5 65.8 57.1 79.7 43.7 55.0 67.9 47.6 55.9 93.9 118.3 191.5 82.8 93.7 82.9 40.1 100.0 61.2 83.2 90.0 99.8 32.2 94.3 36.1 64.1 110.1 57.1 81.5 47.2 36.5 59.4 63.4 76.9 41.8 161.8 84.6 55.2 81.9 58.8 100.8 74.1 78.3 43.5 74.0 50.6 67.4 49.6 97.9 93.1 50.9 65.4 24.3 62.5 89.1 104.9 41.0 130.2 71.3 47.5 57.7 57.5 51.1 89.3 43.4 57.5 104.4 57.9 99.7 55.4 35.9 49.0 44.1 47.5 59.7 48.7 72.3 51.5 51.3 66.6 61.5 47.7 54.6 19.8 64.0 60.4 51.9 75.1 62.4 18.4 18.4 20.0 27.9 18.5 19.0 19.5 18.8 19.7 18.7 18.8 19.6 55.2 25.6 28.1 11.1 52.2 63.9 54.4 191.6 43.9 28.1 45.9 67.9 213.2 64.3 95.6 60.7 27.1 144.6 37.9 46.6 223.0 114.9 56.2 49.6 44.4 69.2 49.6 64.0 13.0 127.1 132.6 64.7 27.0 41.3 45.0 56.2 51.4 85.2 99.3 32.0 11.8 65.6 79.3 33.2 57.1 29.3 66.2 35.7 51.6 2.8 61.3 35.9 56.7 11.1 20.1 113.9 83.4 75.2 71.1 47.2 68.1 203.7 89.0 27.1 32.9 48.5 86.7 167.7 67.0 50.3 65.8 78.5 48.4 122.2 78.5 54.6 MRPL54 ENSG00000183617 "Mitochondrial ribosomal protein L54" Q6P161 19 3762682-3768575 "Predicted intracellular proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 427.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042117, HPA046767" Uncertain Approved Mitochondria No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA042117: AB_2677856, HPA046767: AB_2679795" "unprognostic (2.09e-1)" "unprognostic (1.00e-3)" "unprognostic (3.81e-2)" "unprognostic (1.85e-3)" "unprognostic (1.00e-1)" "unprognostic (4.43e-2)" "unprognostic (1.23e-2)" "unprognostic (1.32e-3)" "unprognostic (7.19e-2)" "unprognostic (1.70e-2)" "unprognostic (2.22e-2)" "unprognostic (2.88e-2)" "unprognostic (1.34e-3)" "unprognostic (1.78e-1)" "unprognostic (2.26e-1)" "unprognostic (2.64e-2)" "unprognostic (6.54e-3)" 56.1 85.5 68.9 41.0 69.0 109.0 54.8 70.6 80.0 47.0 70.5 54.9 53.8 49.8 36.3 58.4 57.8 34.6 78.6 67.5 70.4 78.7 122.9 43.1 63.5 69.5 68.4 46.9 87.8 71.3 64.0 31.4 69.8 57.9 44.0 38.1 71.9 37.1 57.8 55.9 48.8 37.6 69.8 54.4 70.7 54.4 70.1 63.4 57.8 57.8 50.5 50.4 43.8 72.0 115.1 64.4 58.4 57.6 34.2 54.6 49.6 53.8 69.0 126.8 108.5 55.7 39.8 82.1 54.4 66.8 47.6 71.3 77.6 70.9 53.8 53.0 118.4 41.8 33.6 72.0 89.1 89.7 95.0 64.2 121.3 53.2 92.7 49.0 105.8 56.4 80.2 157.1 67.3 77.9 81.1 94.5 77.8 79.8 46.9 69.4 33.2 122.8 97.8 57.9 81.6 67.6 43.8 103.4 83.4 27.8 69.7 126.6 75.5 79.5 45.8 136.5 117.2 95.4 140.5 82.4 78.6 142.3 60.6 96.9 121.2 81.9 103.4 132.8 96.0 139.1 112.5 122.3 134.7 125.8 107.6 99.1 35.3 133.0 133.7 122.7 168.4 144.1 68.9 69.0 70.6 80.0 67.5 70.4 69.5 68.4 69.8 69.8 70.1 72.0 61.1 76.9 79.3 5.5 101.2 49.1 91.9 111.1 63.2 55.6 89.2 98.8 55.2 91.5 91.7 79.1 18.8 134.4 69.7 183.5 358.1 112.7 94.2 90.1 54.7 60.5 105.4 63.1 3.6 193.6 125.7 62.8 90.7 78.8 106.5 47.6 62.4 249.8 157.7 38.7 4.7 234.8 79.3 115.3 65.4 63.0 56.2 90.9 71.2 2.8 120.7 105.1 106.1 2.0 10.1 128.7 185.4 44.8 123.2 116.2 234.4 427.8 76.0 90.9 26.3 65.7 64.4 113.4 47.1 106.7 57.3 176.9 94.6 109.3 171.5 118.2 MRPS10 FLJ10567 ENSG00000048544 "Mitochondrial ribosomal protein S10" P82664 6 42206807-42217861 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 295.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029133, HPA029134" Supported Approved "Actin filaments,Mitochondria" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Actin filaments" "HPA029133: AB_10600084, HPA029134: AB_10600058" "unprognostic (1.06e-1)" "unprognostic (3.90e-2)" "unprognostic (5.55e-2)" "unprognostic (3.77e-3)" "unprognostic (1.70e-1)" "unprognostic (1.78e-3)" "unprognostic (2.37e-2)" "unprognostic (8.65e-2)" "unprognostic (1.50e-3)" "unprognostic (5.13e-3)" "unprognostic (2.78e-3)" "unprognostic (6.29e-2)" "unprognostic (3.17e-2)" "unprognostic (8.54e-2)" "unprognostic (3.45e-1)" "unprognostic (3.36e-2)" "unprognostic (5.04e-2)" 24.7 24.0 16.3 20.3 17.1 24.1 21.6 16.8 18.4 19.4 16.1 20.3 19.1 18.3 18.1 43.3 14.5 15.9 46.6 17.3 17.7 29.1 37.5 15.7 24.3 16.5 16.8 14.6 17.2 22.9 13.2 21.6 16.7 18.4 23.6 18.3 19.9 17.0 73.6 18.4 17.7 22.1 16.1 18.8 18.3 16.2 17.5 24.9 24.1 61.8 27.7 24.2 23.7 18.0 99.4 35.1 36.1 61.8 49.4 47.6 32.2 64.3 63.3 61.0 53.3 40.3 38.2 70.2 41.7 60.2 68.3 35.3 60.3 87.5 81.6 64.5 49.3 62.5 30.9 67.2 51.4 93.1 38.8 41.3 65.9 57.2 121.1 41.4 62.8 73.5 110.5 53.4 74.7 63.5 61.0 67.1 30.7 295.3 57.1 51.7 54.3 66.8 105.1 44.2 55.0 40.6 36.9 49.9 122.0 33.5 83.0 125.2 40.7 51.7 51.0 50.3 96.9 39.6 64.4 149.1 35.3 91.7 52.6 22.4 26.0 20.1 23.9 30.4 28.2 30.1 29.2 28.7 29.4 27.1 29.6 28.9 13.1 29.8 28.8 37.7 35.1 28.0 16.3 17.1 16.8 18.4 17.3 17.7 16.5 16.8 16.7 16.1 17.5 18.0 40.4 22.4 21.6 6.8 41.8 40.5 53.6 61.5 22.8 26.8 35.3 33.4 131.8 20.0 39.6 38.6 31.3 102.0 48.0 25.2 92.0 66.5 7.6 35.3 52.4 41.3 14.9 74.5 7.6 47.0 67.5 42.9 23.4 26.8 32.9 46.1 24.7 58.9 52.8 32.0 9.0 27.6 67.1 24.4 28.0 8.8 28.9 34.8 30.2 2.8 110.6 47.8 60.8 7.5 9.5 61.1 30.5 36.5 41.9 64.9 30.0 86.9 60.5 57.3 19.7 35.2 43.0 75.5 83.8 62.2 40.6 75.4 33.8 65.7 35.3 69.4 MRPS35 "MDS023, MRPS28" ENSG00000061794 "Mitochondrial ribosomal protein S35" P82673 12 27710822-27756295 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 242.6;Proximal tubular cells: 231.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038513 Supported Approved Mitochondria,Cytosol No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Cytosol "HPA038513: AB_10794084" "prognostic unfavorable (9.41e-4)" "unprognostic (8.35e-2)" "prognostic favorable (5.01e-4)" "unprognostic (2.59e-2)" "unprognostic (5.31e-2)" "unprognostic (2.78e-2)" "prognostic unfavorable (1.64e-4)" "unprognostic (7.32e-2)" "unprognostic (2.12e-3)" "unprognostic (2.05e-1)" "unprognostic (3.24e-2)" "unprognostic (7.19e-2)" "prognostic favorable (1.51e-5)" "unprognostic (4.63e-2)" "unprognostic (2.44e-1)" "unprognostic (3.51e-2)" "unprognostic (1.25e-1)" 27.3 42.1 25.0 26.8 26.1 31.2 42.7 26.7 33.4 23.8 28.0 59.2 52.6 25.8 29.4 35.8 29.4 24.1 62.2 26.0 27.2 78.6 77.7 21.6 31.9 25.7 26.0 26.2 27.8 46.9 14.0 29.1 26.5 31.5 61.1 18.4 29.6 24.1 83.3 23.5 46.4 29.8 26.7 21.0 43.9 18.0 26.4 28.3 44.2 72.5 32.1 35.3 20.4 27.9 95.0 102.1 42.4 65.1 58.9 71.8 156.0 61.4 52.6 84.4 76.2 125.0 132.4 88.2 87.5 63.3 65.5 70.0 88.0 77.9 99.1 74.2 82.8 100.2 39.2 103.7 58.5 138.1 51.1 61.4 95.1 71.1 143.2 77.3 69.6 73.0 110.1 58.6 77.9 57.9 96.7 227.0 158.9 231.8 147.7 101.1 109.8 145.3 130.8 77.3 24.0 48.5 84.4 131.0 106.1 93.9 133.6 108.2 54.5 51.4 54.9 117.8 111.4 22.8 36.9 186.8 68.6 104.5 68.5 11.0 21.5 7.8 15.1 38.3 24.1 20.7 18.9 18.7 30.5 19.7 22.3 20.4 1.2 25.9 46.4 14.4 26.4 23.8 25.0 26.1 26.7 33.4 26.0 27.2 25.7 26.0 26.5 26.7 26.4 27.9 25.0 73.7 40.3 13.4 38.2 47.3 42.3 65.0 46.1 20.8 49.8 43.8 94.8 50.1 55.4 51.5 4.2 104.0 21.2 51.8 242.6 92.0 12.6 42.0 42.4 30.1 60.3 26.3 28.0 59.2 113.4 35.9 72.4 40.0 54.5 34.5 18.9 67.1 73.1 18.5 28.0 81.2 40.7 38.4 28.8 9.1 25.4 42.9 42.7 8.4 64.7 27.1 34.0 19.6 25.4 62.2 52.3 24.5 32.1 55.4 63.6 231.4 70.2 18.0 26.3 35.8 39.8 23.9 27.2 68.7 52.1 61.7 34.8 83.8 116.5 46.1 MRPS7 "MRP-S, RP-S7, RPMS7" ENSG00000125445 "Mitochondrial ribosomal protein S7" Q9Y2R9 17 75261674-75266376 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 454.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022522, HPA023007" Supported Approved Mitochondria No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "HPA022522: AB_1854131, HPA023007: AB_1854132" "unprognostic (1.24e-1)" "unprognostic (4.74e-2)" "prognostic favorable (1.12e-4)" "unprognostic (5.82e-3)" "unprognostic (3.62e-2)" "unprognostic (5.05e-3)" "prognostic unfavorable (3.13e-4)" "unprognostic (1.32e-1)" "unprognostic (1.04e-1)" "unprognostic (4.95e-2)" "unprognostic (8.56e-3)" "unprognostic (1.03e-1)" "unprognostic (5.83e-2)" "unprognostic (1.03e-1)" "unprognostic (8.56e-2)" "unprognostic (1.76e-1)" "unprognostic (4.15e-1)" 44.3 58.4 55.5 38.1 55.9 32.9 41.2 60.0 61.9 28.7 59.0 49.9 48.9 28.3 24.4 58.5 39.2 27.1 129.0 55.1 59.3 66.1 64.6 32.4 41.3 57.2 57.5 29.2 39.0 76.6 36.0 40.8 57.6 34.1 48.2 47.3 41.1 35.7 201.3 32.6 40.0 33.8 57.8 39.5 47.5 29.9 59.8 33.6 35.9 212.3 43.6 42.6 35.0 56.3 113.8 188.6 78.8 57.6 63.9 35.7 139.4 73.3 60.9 137.4 101.1 209.8 93.5 96.4 66.4 79.8 91.4 104.5 122.3 135.8 82.2 50.8 173.5 131.8 133.6 201.3 62.5 134.3 69.6 60.0 131.8 108.6 109.6 69.2 177.3 117.8 130.1 93.3 91.1 203.5 151.8 104.7 85.4 157.7 176.2 100.7 229.5 145.2 128.4 124.6 135.8 122.8 93.8 249.9 150.0 83.9 188.4 108.7 72.2 124.0 125.3 68.2 155.7 97.9 61.5 106.6 89.5 88.3 96.9 43.2 155.1 48.2 115.7 161.6 124.2 140.2 112.0 126.0 172.0 128.1 128.6 120.7 11.0 130.5 138.5 164.9 141.6 236.0 55.5 55.9 60.0 61.9 55.1 59.3 57.2 57.5 57.6 57.8 59.8 56.3 44.1 51.3 48.3 12.1 69.3 39.5 75.1 148.1 37.0 65.8 56.5 63.0 77.8 70.1 74.3 57.0 98.0 192.9 63.3 94.1 230.9 112.9 139.2 50.9 43.2 55.6 47.5 61.4 11.8 104.1 175.3 50.2 55.5 43.5 39.3 68.6 45.3 91.7 148.8 47.1 14.0 84.3 77.3 60.0 35.6 454.3 48.4 52.6 42.7 3.7 107.0 85.6 73.2 9.5 11.3 89.8 69.3 39.9 87.7 85.3 129.2 219.3 81.0 114.4 59.2 40.8 73.0 60.5 68.5 68.5 41.9 137.9 53.8 110.0 133.8 77.4 MT-ND4L "MTND4L, NAD4L, ND4L" ENSG00000212907 "Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L" P03901 MT 10470-10766 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Leber hereditary optic neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 132930.7;heart muscle: 145078.7" "Cell type enriched" "Detected in many" 5 "Cardiomyocytes: 30444.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HeLa: 50775.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075648 Approved Centrosome,Mitochondria NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria Centrosome "HPA075648: AB_2686760" "unprognostic (5.81e-2)" "unprognostic (3.46e-2)" "unprognostic (2.76e-2)" "unprognostic (7.91e-2)" "unprognostic (5.64e-2)" "unprognostic (1.05e-1)" "prognostic favorable (4.47e-4)" "unprognostic (1.97e-1)" "unprognostic (4.04e-2)" "unprognostic (4.63e-3)" "unprognostic (6.61e-2)" "unprognostic (7.38e-3)" "unprognostic (1.39e-1)" "unprognostic (3.09e-1)" "unprognostic (3.73e-1)" "unprognostic (2.97e-2)" "unprognostic (5.68e-2)" 20104.7 29874.0 85794.9 4122.5 86270.4 3115.3 14930.3 82985.5 132930.7 6880.0 93989.2 20616.6 9025.8 7679.7 5976.7 10820.3 7752.4 4365.8 145078.7 84214.9 90415.7 46912.7 74928.5 8462.2 2787.1 92948.1 87984.2 6729.2 16038.2 20410.6 9234.3 5840.3 89012.2 16438.2 14044.5 15747.5 12913.6 12715.8 58998.5 13345.9 17015.9 6979.3 79192.1 7285.6 28192.3 9561.4 87700.1 4435.4 11270.7 103082.4 4852.1 15113.7 7437.4 83632.8 4598.0 4121.5 7308.1 7468.2 25088.0 5217.1 3223.3 9523.0 2384.3 1468.4 2651.9 6894.3 4080.7 11229.9 3809.7 6497.0 2387.4 8496.5 1155.8 10210.3 2895.1 4454.2 4711.8 8095.9 50775.4 13024.1 3671.8 8429.4 6965.0 9229.0 10159.4 2792.9 9675.2 10923.1 2983.6 5697.7 4556.7 7771.2 5412.1 8124.5 3199.8 10639.4 1846.3 4811.8 4953.4 1842.5 3155.8 5025.1 7636.0 9464.9 2208.4 2971.3 4666.2 7283.7 3197.8 15599.0 5199.9 10420.1 9592.2 3792.1 4708.5 5630.1 3738.0 6985.1 3552.9 6053.5 2725.1 11018.8 1816.1 16170.2 4327.0 8286.8 2536.0 2849.6 3435.6 4233.2 2723.9 2939.9 2282.7 4618.7 3206.8 4006.1 2010.3 2906.4 2817.9 2884.1 2096.4 2551.4 85794.9 86270.4 82985.5 132930.7 84214.9 90415.7 92948.1 87984.2 89012.2 79192.1 87700.1 83632.8 503.6 224.4 217.6 0.0 2303.6 228.5 254.2 170.4 5991.6 0.0 764.0 886.3 30444.3 1464.1 438.4 323.7 0.0 0.0 449.8 1428.3 90.1 152.9 52.8 870.1 618.8 942.3 256.6 3302.0 0.0 342.2 0.0 1129.2 5335.9 1186.3 479.3 1394.0 1520.3 4413.7 0.0 0.0 0.0 727.8 99.7 1977.9 193.5 286.1 417.2 1043.8 256.1 0.0 312.9 0.0 133.9 0.0 0.0 284.5 867.0 230.9 4395.8 129.7 1228.2 589.4 582.7 0.0 348.4 711.2 1052.8 247.0 207.4 5256.4 242.2 0.0 1387.0 308.6 573.4 207.9 MTCH2 SLC25A50 ENSG00000109919 "Mitochondrial carrier 2" Q9Y6C9 11 47617315-47642607 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 569.2;Proximal tubular cells: 508.1;Spermatocytes: 435.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038390 Approved Approved Mitochondria NA NA 14000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 18: U-2197 - ECM organization" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA038390: AB_10669723" "unprognostic (4.94e-2)" "unprognostic (3.29e-1)" "unprognostic (1.93e-2)" "unprognostic (1.43e-1)" "unprognostic (4.27e-1)" "unprognostic (7.63e-3)" "unprognostic (1.80e-1)" "unprognostic (7.03e-2)" "unprognostic (1.51e-1)" "unprognostic (1.53e-2)" "unprognostic (1.08e-1)" "unprognostic (1.14e-1)" "prognostic favorable (9.05e-6)" "unprognostic (1.12e-2)" "unprognostic (8.75e-2)" "unprognostic (2.25e-1)" "unprognostic (1.77e-1)" 28.8 40.3 13.2 14.1 14.1 12.6 25.3 14.3 15.7 20.5 12.7 41.7 38.9 26.8 19.4 50.3 18.9 11.9 41.0 13.8 15.1 57.3 115.3 20.0 14.7 13.3 14.0 13.6 22.6 21.2 18.5 9.9 13.7 18.3 32.7 16.2 29.8 11.9 81.8 28.7 37.6 21.4 12.8 19.6 22.6 69.8 14.7 14.6 21.6 47.5 23.0 23.2 26.1 14.9 47.8 51.2 42.9 57.9 49.7 45.8 31.6 50.5 46.1 66.7 62.6 40.9 47.2 65.4 26.8 62.3 71.7 58.5 77.7 66.4 80.9 33.0 73.4 37.5 69.3 82.5 68.2 79.1 36.1 52.1 51.5 44.3 65.8 38.6 61.1 55.1 70.9 38.0 82.9 69.3 61.1 59.5 46.4 92.4 77.0 56.1 65.4 47.0 78.5 60.6 51.0 35.7 69.1 68.8 37.1 40.3 99.2 36.4 51.2 60.9 52.9 102.4 65.8 40.5 49.3 73.2 50.4 67.7 55.7 13.3 33.8 14.1 20.3 37.6 19.6 25.1 17.7 19.2 44.0 19.5 15.1 17.6 3.2 22.2 31.5 28.9 24.0 34.1 13.2 14.1 14.3 15.7 13.8 15.1 13.3 14.0 13.7 12.8 14.7 14.9 28.4 22.4 35.9 54.9 39.2 47.0 56.0 169.3 44.9 0.0 50.7 41.3 67.8 71.4 84.0 53.3 0.0 82.8 41.2 98.1 181.9 153.3 569.2 48.8 37.5 31.6 79.8 74.6 47.0 109.4 119.1 40.0 46.4 40.1 37.3 29.3 33.2 289.4 164.2 0.0 50.9 97.0 150.5 65.7 40.3 166.5 28.9 67.5 81.8 22.5 103.9 0.0 30.9 58.8 58.6 93.0 69.7 58.3 70.9 84.9 213.3 508.1 79.0 0.0 32.9 30.0 141.3 435.4 104.4 129.8 54.1 127.8 34.5 74.4 165.5 65.2 MTFP1 "HSPC242, MTP18" ENSG00000242114 "Mitochondrial fission process 1" Q9UDX5 22 30425623-30429054 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 69.7;Exocrine glandular cells: 52.2;Plasma cells: 43.5;Undifferentiated cells: 45.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077396 Approved Mitochondria NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA077396: AB_2686837" "unprognostic (2.19e-2)" "unprognostic (1.18e-1)" "unprognostic (3.12e-1)" "unprognostic (6.20e-2)" "unprognostic (4.86e-2)" "unprognostic (1.72e-3)" "unprognostic (1.52e-3)" "unprognostic (8.98e-2)" "unprognostic (2.07e-1)" "unprognostic (1.65e-1)" "unprognostic (6.37e-3)" "unprognostic (1.54e-1)" "unprognostic (1.49e-1)" "unprognostic (6.40e-2)" "unprognostic (3.06e-2)" "unprognostic (3.84e-1)" "unprognostic (1.66e-2)" 12.9 15.6 8.7 10.1 9.1 14.2 11.6 11.1 9.9 8.3 16.8 17.1 16.8 3.8 15.1 19.8 3.4 8.1 26.2 9.0 10.2 38.9 31.9 11.9 16.5 9.9 9.7 5.0 19.0 21.8 8.1 11.4 9.3 13.5 12.9 23.4 10.1 4.9 26.2 7.6 13.4 4.7 9.1 20.9 19.7 4.0 10.8 7.8 8.5 19.3 14.8 13.7 7.6 8.6 91.9 69.5 23.8 37.1 5.1 4.1 27.2 8.6 8.2 51.3 78.5 33.6 52.4 99.5 25.3 6.0 41.3 46.5 74.0 77.6 34.7 56.2 96.5 26.7 38.6 64.9 14.8 66.7 52.7 7.6 25.7 31.4 47.4 15.7 43.5 45.1 51.2 35.5 16.3 109.5 63.3 71.8 41.5 82.9 73.2 85.6 23.1 87.3 61.0 24.8 40.6 44.5 19.9 90.6 35.6 16.9 28.8 31.4 18.4 55.9 72.4 27.6 26.3 17.8 15.5 86.1 22.4 75.9 23.7 0.2 14.3 0.1 49.2 17.1 65.5 34.0 39.6 42.3 20.3 23.7 41.7 48.2 1.8 14.0 11.6 10.5 36.0 25.6 8.7 9.1 11.1 9.9 9.0 10.2 9.9 9.7 9.3 9.1 10.8 8.6 5.3 6.4 3.0 3.9 21.7 5.6 1.8 12.0 6.2 0.0 10.1 3.7 4.4 7.2 6.7 3.7 0.0 13.4 14.8 33.2 15.6 69.7 0.1 1.9 1.4 5.8 8.4 9.2 0.8 52.2 30.4 2.5 20.9 2.6 9.5 0.4 5.0 11.1 17.6 0.0 2.7 28.1 2.0 10.3 9.6 0.2 0.6 6.4 3.6 1.0 36.6 0.0 10.3 0.5 0.3 40.3 13.8 0.4 43.5 3.5 28.3 11.8 1.9 0.0 0.0 1.5 5.1 0.6 2.1 16.5 5.5 16.8 29.6 0.7 45.3 2.2 MTFR1L FAM54B ENSG00000117640 "Mitochondrial fission regulator 1 like" Q9H019 1 25818640-25832942 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 161.1;Early spermatids: 216.1;Late spermatids: 590.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027124, HPA027130" Approved Approved "Cell Junctions,Mitochondria" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "Cell Junctions" "HPA027124: AB_10600211, HPA027130: AB_10611251" "unprognostic (9.90e-2)" "unprognostic (6.86e-3)" "unprognostic (9.29e-2)" "prognostic favorable (6.81e-4)" "unprognostic (1.16e-1)" "unprognostic (1.58e-2)" "unprognostic (1.43e-1)" "unprognostic (4.52e-3)" "unprognostic (2.12e-1)" "unprognostic (2.24e-1)" "unprognostic (9.89e-3)" "unprognostic (5.33e-2)" "prognostic favorable (5.89e-12)" "unprognostic (1.41e-1)" "unprognostic (1.22e-1)" "unprognostic (2.69e-1)" "unprognostic (1.33e-1)" 39.0 138.0 79.6 22.2 82.8 17.8 37.4 80.0 88.4 51.0 84.6 74.1 46.8 51.0 57.8 39.4 44.9 32.7 169.1 81.7 81.3 71.7 91.3 32.4 25.8 80.2 83.8 68.4 46.0 106.0 51.6 40.7 79.6 55.8 37.3 62.1 43.3 70.1 221.8 35.6 46.9 50.0 78.6 44.2 56.6 82.5 83.2 24.7 48.1 239.7 26.3 58.3 40.5 78.5 19.5 26.7 53.2 53.6 67.6 63.8 22.2 44.7 63.7 45.2 49.9 8.7 39.7 6.6 38.9 80.1 40.0 17.4 44.1 38.6 44.8 43.9 39.8 55.6 44.3 35.9 64.6 45.5 52.9 65.3 36.4 48.3 36.1 67.0 37.9 27.0 34.7 29.2 66.1 21.6 26.3 33.6 29.4 26.0 39.4 26.0 47.4 19.8 47.1 18.3 53.6 48.5 33.6 32.4 67.8 35.8 26.7 43.1 38.6 36.7 28.9 86.6 28.5 30.5 19.3 23.2 63.6 62.5 41.2 71.7 50.5 111.7 25.7 50.8 15.6 28.1 24.1 22.9 55.0 28.8 25.4 23.1 13.6 27.6 58.3 22.7 27.3 51.1 79.6 82.8 80.0 88.4 81.7 81.3 80.2 83.8 79.6 78.6 83.2 78.5 18.7 16.0 24.5 24.2 14.1 13.5 20.8 38.6 25.0 0.0 21.6 23.6 161.1 25.8 21.7 22.0 0.0 55.9 14.8 15.7 103.7 32.4 216.1 11.3 16.7 17.1 15.6 12.4 18.2 33.5 36.7 28.4 21.4 10.6 36.1 21.9 21.4 35.5 34.9 0.0 24.1 14.9 34.6 15.1 17.3 590.4 34.2 25.6 44.4 6.5 43.5 0.0 12.3 12.5 15.2 27.7 15.0 39.1 15.4 16.2 39.3 70.6 10.5 0.0 26.3 23.3 31.3 144.7 49.9 15.4 12.9 59.4 13.1 29.8 18.0 16.5 MTX1 "MTX, MTXN" ENSG00000173171 "Metaxin 1" Q13505 1 155208695-155213824 "Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 7 "Early spermatids: 601.3;Late spermatids: 1473.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011543 Uncertain Approved Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 43: Testis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "HPA011543: AB_1853824" "unprognostic (2.57e-1)" "unprognostic (9.51e-3)" "unprognostic (3.27e-1)" "unprognostic (5.98e-3)" "unprognostic (1.60e-1)" "unprognostic (2.62e-2)" "unprognostic (1.12e-2)" "unprognostic (1.80e-1)" "unprognostic (8.38e-2)" "unprognostic (1.28e-2)" "unprognostic (1.71e-1)" "unprognostic (6.78e-2)" "prognostic unfavorable (3.39e-4)" "unprognostic (1.30e-2)" "unprognostic (1.70e-1)" "unprognostic (1.37e-1)" "unprognostic (1.96e-2)" 29.3 33.2 23.9 16.1 24.5 39.1 28.2 25.2 29.2 22.3 29.2 25.9 18.9 25.3 17.8 33.0 31.0 13.1 22.1 23.2 24.2 34.1 44.8 22.9 19.6 24.8 24.7 17.6 27.7 37.7 20.3 20.8 24.5 22.1 18.8 3.7 31.6 21.7 17.5 25.5 23.0 18.6 24.7 29.3 28.1 90.3 24.8 20.9 24.4 16.7 21.2 20.7 21.2 25.3 54.3 87.6 27.3 39.3 49.9 44.8 86.4 27.4 55.0 79.4 55.1 109.5 88.2 44.3 88.2 63.4 25.2 52.8 40.6 77.4 28.8 32.9 95.4 28.3 64.0 107.1 78.8 52.5 38.0 57.5 71.2 82.2 54.9 30.4 71.2 64.4 58.1 21.5 47.9 131.7 59.6 65.9 54.7 76.5 100.2 48.3 17.2 105.4 73.1 46.2 44.5 55.3 34.0 106.3 31.0 41.6 86.2 84.1 30.0 37.8 42.6 25.4 46.9 41.1 37.3 46.2 50.1 26.8 41.3 32.8 69.0 17.4 24.2 38.3 23.2 41.6 29.6 25.7 60.8 37.7 29.3 26.5 114.2 34.6 22.2 32.9 39.0 40.6 23.9 24.5 25.2 29.2 23.2 24.2 24.8 24.7 24.5 24.7 24.8 25.3 26.0 9.6 17.0 4.9 28.9 20.3 42.0 91.3 26.7 0.0 41.8 42.4 1.1 27.1 45.1 35.0 0.0 107.5 17.1 36.5 97.8 80.1 601.3 56.6 35.1 24.7 19.8 14.7 2.8 84.7 130.7 33.6 40.8 30.1 26.6 42.2 23.9 54.4 97.3 0.0 3.6 42.3 54.9 37.1 23.3 1473.9 43.2 38.9 49.8 1.0 65.1 0.0 37.0 3.0 4.8 72.7 48.4 39.5 39.3 41.6 44.3 144.6 61.2 0.0 46.0 29.2 58.4 105.2 52.9 34.9 21.0 88.7 22.5 43.9 54.6 42.6 MTX3 ENSG00000177034 "Metaxin 3" Q5HYI7 5 79976716-79991262 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047858, HPA062061" Approved Approved Mitochondria NA NA "Cluster 30: Non-specific - Translation" "Cluster 51: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" Mitochondria "HPA047858: AB_2680185, HPA062061: AB_2684672" "unprognostic (2.56e-2)" "unprognostic (2.32e-1)" "unprognostic (2.47e-2)" "unprognostic (4.21e-2)" "unprognostic (4.59e-1)" "unprognostic (1.88e-2)" "prognostic unfavorable (5.08e-5)" "unprognostic (4.02e-2)" "unprognostic (2.65e-2)" "prognostic unfavorable (2.54e-4)" "unprognostic (8.58e-2)" "unprognostic (8.46e-2)" "unprognostic (5.08e-2)" "unprognostic (1.01e-2)" "unprognostic (1.11e-2)" "unprognostic (3.09e-2)" "unprognostic (2.28e-1)" 6.8 10.0 5.9 6.2 6.8 6.4 8.1 6.0 7.1 8.2 4.8 8.6 4.4 9.2 6.7 7.9 8.3 3.9 7.7 6.9 5.9 6.9 5.6 5.5 8.3 6.2 6.1 12.5 7.2 11.8 7.3 4.5 6.7 7.8 4.9 11.9 8.3 6.8 8.7 7.6 9.6 6.1 5.4 8.3 7.4 5.1 6.8 3.8 8.8 5.5 7.9 7.9 7.6 6.2 8.6 4.9 13.1 7.1 6.3 11.3 3.3 8.2 5.9 6.6 7.3 2.1 9.1 13.6 2.4 7.7 11.0 9.9 0.0 18.1 12.4 3.6 8.0 5.7 14.7 6.8 11.8 0.0 6.7 9.0 18.0 11.4 20.1 9.3 4.6 0.0 3.0 7.5 11.3 9.2 0.0 0.1 13.4 2.8 5.1 0.0 19.7 5.8 6.0 9.7 17.1 13.2 10.8 7.4 15.9 10.1 12.1 9.7 5.3 11.9 9.7 9.2 18.0 10.5 10.8 11.9 17.8 0.0 15.0 0.3 0.2 0.2 0.6 0.2 0.4 0.8 0.6 0.5 0.1 0.5 0.8 0.6 0.2 0.4 0.1 0.2 0.4 0.2 5.9 6.8 6.0 7.1 6.9 5.9 6.2 6.1 6.7 5.4 6.8 6.2 7.6 28.9 5.3 18.9 8.4 1.5 4.9 2.7 9.6 0.0 9.8 6.7 9.4 15.7 8.0 12.9 0.0 5.1 6.2 2.5 5.9 3.9 2.7 9.2 16.4 7.2 0.0 3.8 27.1 2.5 3.2 9.9 5.1 8.6 1.3 20.6 10.8 7.9 3.2 0.0 24.5 4.4 4.1 3.5 1.7 4.1 12.8 3.4 0.0 5.6 2.8 0.0 5.2 23.6 25.0 5.3 5.3 12.4 5.1 8.7 3.9 8.6 12.5 0.0 13.1 13.4 9.8 8.8 7.5 11.5 3.4 1.8 8.1 15.5 6.0 5.8 MYBPH ENSG00000133055 "Myosin binding protein H" Q13203 1 203167811-203175826 "Predicted intracellular proteins" "Cell adhesion" "Muscle protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "salivary gland: 16.2;skeletal muscle: 74.2;tongue: 19.6" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 1.3;Hofbauer cells: 1.0;Microglial cells: 1.0;Skeletal myocytes: 2.5" "Cancer enriched" "Detected in many" 4 "head and neck cancer: 20.2" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "plasmacytoid DC: 2.5" "Lineage enriched" "Detected in single" 5 "dendritic cells: 2.5" "Group enriched" "Detected in some" 5 "CACO-2: 30.6;HSkMC: 56.7;THP-1: 15.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA061383 Enhanced Approved Nucleoplasm,Nucleoli,Mitochondria NA NA 9700 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 39: CACO-2 - Unknown function" "Cluster 37: Myocytes - Muscle contraction" "Nucleoplasm, Mitochondria" Nucleoli "HPA061383: AB_2684497" "unprognostic (2.26e-4)" "unprognostic (2.04e-1)" "unprognostic (3.50e-1)" "unprognostic (1.06e-1)" "unprognostic (3.82e-2)" "unprognostic (1.32e-3)" "unprognostic (3.42e-1)" "unprognostic (6.84e-2)" "unprognostic (1.18e-1)" "unprognostic (2.96e-1)" "unprognostic (2.86e-1)" "unprognostic (1.75e-1)" "unprognostic (7.62e-4)" "unprognostic (1.51e-1)" "unprognostic (3.34e-2)" "unprognostic (1.14e-1)" "unprognostic (1.74e-1)" 0.2 0.0 0.7 0.5 1.3 0.2 0.5 0.7 2.0 0.1 0.9 0.0 0.0 0.2 0.0 1.1 0.2 0.0 0.1 0.9 0.7 1.9 3.4 0.3 0.1 1.7 1.3 0.0 0.0 0.0 1.3 0.1 3.3 3.3 0.0 0.1 16.2 0.0 74.2 0.5 0.0 0.0 0.0 1.0 0.0 0.0 2.8 1.8 0.1 19.6 0.2 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.4 7.3 0.0 0.0 0.0 0.0 0.0 30.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 56.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 4.3 0.2 0.0 1.0 0.1 0.0 0.0 0.0 0.9 2.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 15.1 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.5 0.0 0.0 0.7 1.3 0.7 2.0 0.9 0.7 1.7 1.3 3.3 0.0 2.8 1.0 0.0 0.0 1.3 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.5 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 MYCBP AMY-1 ENSG00000214114 "MYC binding protein" Q99417 1 38862493-38873368 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 106.0;Respiratory ciliated cells: 142.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA041188, HPA078331" Supported Approved Nucleoplasm,Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm Mitochondria "HPA041188: AB_10794405, HPA078331: AB_2686882" "unprognostic (2.42e-2)" "unprognostic (6.60e-2)" "unprognostic (3.85e-3)" "unprognostic (9.46e-3)" "unprognostic (8.77e-2)" "unprognostic (2.16e-1)" "prognostic unfavorable (6.03e-6)" "unprognostic (7.59e-2)" "unprognostic (3.00e-3)" "unprognostic (5.03e-3)" "unprognostic (4.41e-3)" "unprognostic (2.34e-3)" "unprognostic (5.81e-3)" "unprognostic (8.02e-3)" "unprognostic (1.30e-1)" "unprognostic (1.20e-2)" "unprognostic (2.41e-2)" 11.5 11.0 2.6 16.9 3.4 16.1 18.7 3.4 4.3 12.5 3.7 22.6 16.3 9.6 17.4 23.1 27.1 11.3 8.4 2.4 2.9 18.0 11.5 12.4 16.3 5.6 7.4 6.7 16.1 18.6 8.7 19.3 4.5 14.9 22.5 8.6 16.8 16.1 12.1 13.2 21.6 11.7 2.7 11.2 16.1 15.5 3.2 12.6 18.5 5.6 17.9 16.8 11.7 5.6 51.3 22.5 18.0 13.0 10.7 18.4 74.4 38.9 12.9 38.6 29.7 27.8 56.5 42.1 43.3 18.3 6.5 35.8 29.1 51.9 46.0 52.3 49.7 44.1 29.5 26.7 2.8 107.7 38.9 16.4 38.9 32.3 20.3 14.7 28.3 45.6 64.1 35.8 41.4 31.3 35.1 54.9 47.3 75.3 53.4 33.4 54.4 58.0 50.3 40.6 34.9 23.5 37.0 47.5 25.7 42.4 33.5 52.6 23.2 20.4 33.5 31.2 45.6 25.3 48.7 45.1 20.5 63.9 26.0 51.6 32.8 85.2 18.8 39.7 21.6 22.0 22.1 22.5 40.9 17.7 18.8 21.4 64.4 27.2 38.0 54.3 33.8 22.6 2.6 3.4 3.4 4.3 2.4 2.9 5.6 7.4 4.5 2.7 3.2 5.6 9.2 9.6 13.1 0.0 18.7 10.6 15.7 31.8 22.2 0.7 25.9 14.1 7.9 20.0 37.5 27.6 0.0 106.0 26.7 35.1 64.6 27.0 68.3 84.1 11.4 11.8 9.6 38.7 0.0 27.2 86.2 9.5 21.9 17.9 26.1 9.3 8.9 15.3 21.0 10.1 0.0 25.2 26.4 15.0 14.8 25.2 7.2 20.5 19.6 0.0 31.0 5.5 18.6 0.0 0.0 29.7 40.2 9.1 69.6 18.2 31.2 50.3 142.2 5.0 6.6 6.7 14.8 29.9 64.5 53.4 17.8 88.1 19.3 14.0 31.5 22.4 MYD88 ENSG00000172936 "MYD88 innate immune signal transduction adaptor" Q99836 3 38138478-38143022 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 75.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 172.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009104 Approved Supported Vesicles,Mitochondria,Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "Vesicles, Mitochondria" "CAB009104: AB_2146724" "prognostic favorable (8.45e-4)" "unprognostic (1.19e-1)" "unprognostic (4.31e-2)" "unprognostic (2.51e-2)" "unprognostic (4.77e-2)" "unprognostic (4.38e-3)" "unprognostic (4.37e-2)" "unprognostic (3.63e-1)" "unprognostic (1.67e-1)" "unprognostic (7.28e-2)" "unprognostic (1.01e-2)" "unprognostic (7.30e-2)" "unprognostic (2.11e-2)" "unprognostic (4.41e-1)" "unprognostic (4.17e-2)" "unprognostic (1.65e-1)" "unprognostic (2.08e-2)" 20.1 14.2 6.9 43.5 7.4 51.8 15.0 7.2 7.5 15.2 8.0 30.3 32.2 12.1 18.6 36.6 14.4 23.5 9.4 6.7 7.7 13.7 61.1 42.6 35.2 9.5 7.5 11.4 11.6 11.6 9.2 22.6 8.0 14.3 31.7 2.1 18.0 12.0 3.2 17.7 32.2 24.5 8.6 40.7 27.6 7.7 9.2 38.3 9.4 8.8 41.6 47.4 20.3 8.5 25.1 34.2 5.9 33.2 25.0 32.0 10.8 23.6 39.0 68.1 72.9 22.7 30.9 52.8 13.8 44.7 15.8 30.9 43.2 24.2 22.1 39.5 8.7 28.5 16.6 36.6 21.4 36.2 72.0 38.4 26.6 39.2 15.3 13.2 39.9 40.3 13.3 22.3 36.8 25.7 61.3 12.2 22.1 52.8 35.7 24.8 7.0 23.1 37.6 58.9 3.0 12.0 33.4 172.1 22.3 4.8 25.8 40.8 35.5 13.8 7.9 60.6 24.0 28.9 32.9 38.5 25.0 63.0 28.9 288.5 236.9 296.9 67.2 333.6 58.1 43.7 60.6 69.3 203.6 35.2 42.1 59.5 284.7 54.6 436.1 99.9 87.4 257.3 6.9 7.4 7.2 7.5 6.7 7.7 9.5 7.5 8.0 8.6 9.2 8.5 13.4 6.4 15.2 2.0 19.5 14.4 13.5 12.7 14.2 1.0 11.3 10.8 1.6 5.7 16.4 5.5 0.0 14.6 35.3 40.8 7.9 24.5 1.4 10.9 30.2 15.9 9.6 9.7 0.2 27.3 24.4 10.8 23.9 18.6 24.1 10.0 10.4 33.2 32.2 0.0 0.4 14.9 10.2 75.4 40.5 0.9 13.7 61.5 3.6 1.9 58.1 4.1 28.8 2.5 0.3 64.0 34.8 10.5 12.9 16.0 28.0 12.2 12.1 0.1 13.1 4.3 7.2 8.6 0.6 15.1 17.2 12.0 19.6 10.2 15.9 49.4 MYH10 NMMHCB ENSG00000133026 "Myosin heavy chain 10" P35580 17 8474207-8630761 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Cell shape" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 171.9;Excitatory neurons: 221.3;Inhibitory neurons: 151.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 216.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017180, HPA047541, HPA057198" Enhanced Supported "Actin filaments,Mitochondria,Cytosol" NA NA 28000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 47: Cytotrophoblasts - Unknown function" "Actin filaments" "Mitochondria, Cytosol" "CAB017180: , HPA047541: AB_2680081, HPA057198: AB_2683364" "unprognostic (4.67e-2)" "unprognostic (9.64e-3)" "unprognostic (1.13e-1)" "unprognostic (2.52e-3)" "unprognostic (2.40e-1)" "unprognostic (2.33e-2)" "unprognostic (2.75e-1)" "unprognostic (6.45e-2)" "unprognostic (4.77e-2)" "unprognostic (1.11e-1)" "unprognostic (1.39e-3)" "unprognostic (1.69e-2)" "prognostic favorable (1.38e-4)" "unprognostic (2.02e-2)" "unprognostic (2.73e-1)" "unprognostic (5.58e-2)" "prognostic unfavorable (6.42e-4)" 27.3 16.9 12.6 6.1 18.9 13.4 14.7 7.0 29.0 19.6 12.6 12.2 2.3 27.8 16.8 6.6 25.2 26.1 38.9 17.9 8.0 32.5 18.9 66.9 6.5 9.6 7.3 25.9 9.8 13.8 17.7 53.4 9.6 17.7 3.8 22.5 6.6 26.6 4.9 7.9 5.8 22.1 0.5 4.6 9.5 7.4 11.0 5.8 13.6 8.2 4.0 10.5 10.3 13.2 54.1 35.1 216.3 72.7 27.7 33.1 97.1 44.2 39.7 52.2 55.8 94.5 8.0 0.5 28.6 43.9 28.4 5.2 108.7 53.0 58.1 1.2 88.3 62.3 21.7 83.0 64.7 5.4 4.2 47.3 18.9 67.7 26.1 32.1 85.3 70.9 88.1 0.2 32.9 21.6 67.2 1.7 102.1 3.6 7.7 105.9 64.2 0.2 59.1 22.3 17.7 96.8 69.2 3.4 68.1 165.0 18.3 3.6 2.8 48.7 35.6 0.3 38.5 8.3 10.8 13.4 0.3 5.0 111.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 12.6 18.9 7.0 29.0 17.9 8.0 9.6 7.3 9.6 0.5 11.0 13.2 43.0 22.4 14.1 43.1 1.1 4.7 9.5 11.2 9.6 37.1 18.7 16.4 33.5 12.8 11.5 101.2 50.1 171.9 1.0 0.8 17.6 13.7 49.1 28.1 37.6 30.6 2.4 43.5 221.3 1.7 88.6 58.0 3.1 28.5 1.3 41.6 55.6 15.3 15.8 35.3 151.1 1.9 6.1 2.7 3.7 28.6 3.7 1.3 1.8 15.9 0.7 25.9 2.1 96.5 15.5 1.9 0.7 39.9 0.6 7.6 0.0 14.0 21.7 39.4 0.0 12.4 23.6 15.6 27.8 9.5 4.0 76.5 2.0 28.0 2.2 4.4 MYL3 "CMH8, MLC1SB, MLC1V, VLC1" ENSG00000160808 "Myosin light chain 3" P08590 3 46835111-46882172 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 9155.0;skeletal muscle: 5135.3;tongue: 2074.2" "Cell type enriched" "Detected in some" 53 "Cardiomyocytes: 3626.2" "Group enriched" "Detected in many" 4 "head and neck cancer: 3.0;prostate cancer: 3.4;renal cancer: 8.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 8.6;HSkMC: 8.7;RPTEC TERT1: 34.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA016564, CAB018662, HPA046859, HPA063034" Enhanced Approved Nucleoli,Mitochondria NA NA 7300000 "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoli, Mitochondria" "CAB018662: AB_627952, HPA016564: AB_1854244, HPA046859: AB_2679842, HPA063034: AB_2684927" "unprognostic (3.11e-1)" "unprognostic (2.64e-2)" "unprognostic (5.55e-2)" "unprognostic (1.51e-1)" "unprognostic (1.77e-1)" "unprognostic (4.44e-2)" "unprognostic (9.67e-3)" "unprognostic (3.37e-2)" "unprognostic (4.72e-3)" "unprognostic (3.63e-2)" "unprognostic (1.08e-1)" "unprognostic (7.88e-2)" "prognostic favorable (1.22e-8)" "unprognostic (1.16e-3)" "unprognostic (9.45e-3)" "unprognostic (7.18e-5)" "unprognostic (2.53e-3)" 5.8 4.1 11.3 0.9 11.1 1.5 8.9 11.4 14.8 6.7 8.4 2.5 1.6 3.3 3.4 157.0 4.2 3.6 9155.0 11.0 12.8 50.3 4.1 5.7 3.3 15.2 13.0 5.2 2.7 1.3 1.7 4.7 12.1 25.1 0.8 1.9 19.6 1.5 5135.3 4.0 2.3 2.0 13.2 7.9 2.1 2.3 12.6 0.7 2.4 2074.2 0.5 2.4 4.7 13.2 0.5 0.7 0.4 0.3 4.4 1.5 3.6 0.7 0.4 0.4 0.6 8.6 0.8 1.6 1.4 0.1 0.2 0.5 0.4 0.1 0.7 0.3 0.1 0.8 2.6 0.3 0.7 0.9 0.8 8.7 0.2 0.3 0.1 0.2 0.1 0.5 0.4 1.2 0.2 1.2 0.3 0.5 1.0 0.4 0.4 0.9 0.3 0.1 34.2 1.3 0.6 0.4 0.3 0.7 0.1 0.7 0.3 0.5 0.2 1.0 0.8 0.6 0.3 0.5 0.4 0.7 0.3 0.8 0.8 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.2 0.0 0.4 0.1 0.1 0.3 0.0 0.1 0.4 0.0 0.0 11.3 11.1 11.4 14.8 11.0 12.8 15.2 13.0 12.1 13.2 12.6 13.2 0.7 0.0 0.0 1.0 0.0 0.8 0.2 0.0 0.0 0.2 2.3 0.1 3626.2 0.0 0.0 1.8 0.0 0.4 0.0 0.0 54.8 0.0 2.4 0.1 2.2 32.8 0.0 0.0 0.1 0.0 16.4 23.7 0.0 0.0 0.0 0.0 1.1 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.6 12.8 1.2 0.7 0.0 0.0 0.0 2.8 0.0 0.5 0.0 0.0 0.0 0.7 0.0 0.0 0.0 68.1 0.0 0.4 6.6 27.9 20.4 0.2 0.5 0.0 0.4 0.8 0.4 0.1 0.0 0.0 MYMX MINION ENSG00000262179 "Myomixer, myoblast fusion factor" A0A1B0GTQ4 6 44216926-44218234 "Predicted intracellular proteins" Myogenesis "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "adipose tissue: 7.7;breast: 6.9;pancreas: 5.6;stomach 1: 2.3" "Group enriched" "Detected in some" 4 "Adipocytes: 5.5;Distal tubular cells: 3.9;Exocrine glandular cells: 2.2;Extravillous trophoblasts: 1.6" "Cancer enhanced" "Detected in some" "testis cancer: 2.5" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 106 "plasmacytoid DC: 10.6" "Lineage enriched" "Detected in single" 106 "dendritic cells: 10.6" "Cell line enriched" "Detected in some" 31 "RH-30: 134.6" "Not detected" "Not detected" HPA051451 Supported Approved Vesicles,Mitochondria,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "Mitochondria, Cytosol" "HPA051451: " "unprognostic (1.24e-1)" "unprognostic (8.55e-2)" "unprognostic (6.86e-2)" "unprognostic (6.51e-3)" "unprognostic (2.78e-1)" "unprognostic (1.26e-1)" "unprognostic (5.27e-2)" "unprognostic (2.10e-3)" "unprognostic (4.32e-1)" "unprognostic (1.77e-1)" "unprognostic (8.71e-2)" "unprognostic (2.70e-2)" "unprognostic (2.01e-4)" "unprognostic (1.63e-2)" "unprognostic (1.33e-2)" "unprognostic (1.77e-2)" "unprognostic (2.67e-1)" 7.7 0.1 0.0 0.2 0.0 0.0 6.9 0.1 0.1 0.2 0.0 0.3 0.0 0.1 0.2 0.2 0.1 0.5 1.0 0.0 0.0 0.7 0.1 0.4 0.6 0.1 0.0 0.1 5.6 0.0 0.0 0.0 0.1 0.1 0.1 0.0 1.1 0.0 0.4 0.9 0.5 0.1 0.0 0.8 2.3 0.4 0.0 0.8 0.4 0.2 0.3 0.5 0.2 0.1 0.0 0.0 0.2 0.0 0.1 0.0 4.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 3.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.0 1.0 0.0 0.0 0.0 134.6 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 1.7 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.9 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 2.2 1.6 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 MYOM2 ENSG00000036448 "Myomesin 2" P54296 8 2045046-2165552 "Predicted intracellular proteins" "Muscle protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "heart muscle: 342.6;skeletal muscle: 387.9" "Group enriched" "Detected in many" 6 "Cardiomyocytes: 632.6;dendritic cells: 234.9;NK-cells: 268.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "HEK 293: 5.3;SCLC-21H: 2.2;U-266/84: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA001765, HPA005953" Enhanced Approved Mitochondria NA NA 290000 "Cluster 38: Heart - Muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA001765: AB_1079443, HPA005953: AB_1854258" "unprognostic (2.81e-2)" "unprognostic (1.11e-3)" "unprognostic (8.19e-2)" "unprognostic (1.35e-3)" "unprognostic (2.11e-1)" "unprognostic (1.86e-2)" "unprognostic (2.30e-5)" "unprognostic (1.10e-1)" "unprognostic (5.17e-2)" "unprognostic (1.34e-2)" "unprognostic (9.56e-2)" "unprognostic (2.54e-2)" "unprognostic (3.89e-2)" "unprognostic (2.71e-2)" "unprognostic (9.01e-2)" "unprognostic (3.22e-1)" "unprognostic (1.14e-1)" 0.1 0.2 0.3 0.1 1.1 0.2 6.1 1.8 1.6 0.2 0.0 0.6 0.2 0.3 0.7 1.2 0.3 0.1 342.6 1.0 0.0 2.7 0.4 0.7 0.1 0.0 0.0 0.1 0.2 0.0 0.2 0.3 0.0 3.7 0.1 0.4 1.9 0.6 387.9 0.8 0.4 0.4 0.0 2.2 0.3 0.4 0.1 0.0 0.1 62.4 0.0 0.4 0.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 5.3 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.1 1.8 1.6 1.0 0.0 0.0 0.0 0.0 0.0 0.1 1.3 3.7 6.4 3.0 11.8 1.6 3.6 2.7 2.0 1.2 3.2 2.7 5.1 632.6 20.0 1.0 3.7 0.0 0.0 234.9 1.8 13.7 4.6 15.2 2.7 1.8 5.6 0.0 3.6 21.8 1.7 0.1 26.7 0.5 1.9 5.7 1.5 4.6 6.8 1.4 6.7 2.8 2.1 2.0 2.7 5.1 8.3 0.6 4.8 3.6 3.7 3.0 7.3 268.8 1.5 2.0 2.5 0.8 1.5 11.1 1.2 1.2 26.0 5.3 4.8 0.0 11.6 13.9 55.9 21.4 1.3 2.8 0.1 22.3 1.5 1.2 1.4 MYORG "KIAA1161, NET37" ENSG00000164976 "Myogenesis regulating glycosidase (putative)" Q6NSJ0 9 34366666-34376898 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 84.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Cytotrophoblasts: 55.5;Exocrine glandular cells: 11.8;Pancreatic endocrine cells: 10.3;Proximal tubular cells: 9.2;Syncytiotrophoblasts: 17.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 35.4;SK-BR-3: 56.8;T-47d: 52.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060533, HPA067487" Enhanced Approved Mitochondria NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 80: Striated muscle - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA060533: AB_2684311, HPA067487: AB_2685848" "unprognostic (6.56e-2)" "unprognostic (1.51e-1)" "unprognostic (3.03e-2)" "prognostic unfavorable (6.96e-4)" "unprognostic (2.44e-1)" "unprognostic (1.20e-1)" "unprognostic (2.44e-1)" "unprognostic (2.03e-2)" "unprognostic (1.55e-1)" "unprognostic (4.68e-3)" "unprognostic (1.91e-3)" "unprognostic (3.20e-1)" "prognostic favorable (1.20e-13)" "unprognostic (4.08e-3)" "unprognostic (3.68e-1)" "unprognostic (3.09e-1)" "unprognostic (1.00e-3)" 8.1 6.2 30.6 3.4 30.3 2.0 3.4 27.1 31.5 1.7 16.8 19.0 27.3 2.7 1.9 5.3 4.5 6.1 3.9 28.4 28.2 14.5 41.5 3.2 1.5 34.0 33.5 1.0 11.1 1.5 5.5 19.8 28.7 3.2 16.2 3.4 5.6 5.2 84.2 3.7 25.8 4.4 24.5 1.4 15.0 1.3 31.8 1.1 1.9 39.2 1.8 3.1 2.4 24.2 8.1 5.5 9.2 5.6 3.8 1.2 19.7 1.4 1.1 0.8 1.3 13.9 8.3 4.4 15.9 1.4 4.0 16.4 6.7 15.5 1.1 1.4 3.6 0.8 24.6 35.4 0.5 0.8 2.7 1.8 7.2 2.6 3.0 4.3 3.8 3.3 1.1 4.2 2.0 13.4 2.5 1.2 5.5 27.4 4.4 4.0 4.6 1.3 4.9 2.9 1.3 13.0 10.8 56.8 0.9 7.8 52.8 1.3 3.2 1.8 11.0 1.6 3.5 2.8 6.5 1.6 1.6 3.1 1.6 0.4 0.1 0.2 0.7 0.1 0.5 0.2 0.4 0.4 0.0 0.2 0.2 0.3 0.3 0.4 0.1 0.1 0.6 0.1 30.6 30.3 27.1 31.5 28.4 28.2 34.0 33.5 28.7 24.5 31.8 24.2 3.9 9.6 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.0 2.7 0.0 0.0 2.5 3.7 0.0 55.5 0.3 0.0 1.9 5.7 0.0 3.4 0.7 2.1 0.0 0.0 0.0 11.8 3.6 1.1 0.0 2.0 1.3 0.2 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 0.0 9.2 2.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 17.4 0.3 0.1 0.0 0.0 NACC2 "BEND9, BTBD14A, BTBD31, MGC23427" ENSG00000148411 "NACC family member 2" Q96BF6 9 136006537-136095289 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 120.6" "Cell type enriched" "Detected in many" 4 "Late spermatids: 305.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 49.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047924, HPA052962" Approved Approved Nucleoli,Mitochondria NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 20: HeLa - Mitochondria" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoli, Mitochondria" "HPA047924: AB_2680212, HPA052962: AB_2681998" "unprognostic (1.13e-2)" "unprognostic (1.52e-1)" "unprognostic (1.90e-2)" "unprognostic (8.73e-3)" "unprognostic (1.31e-1)" "unprognostic (1.32e-1)" "unprognostic (9.25e-3)" "unprognostic (2.25e-2)" "unprognostic (1.23e-1)" "unprognostic (4.92e-2)" "unprognostic (1.15e-2)" "unprognostic (2.23e-1)" "prognostic favorable (8.28e-5)" "prognostic favorable (8.63e-4)" "unprognostic (1.71e-1)" "unprognostic (4.98e-2)" "unprognostic (4.12e-2)" 12.3 11.4 80.9 8.7 100.0 2.0 8.0 115.6 74.1 9.7 26.5 32.7 6.2 20.9 4.1 8.5 12.8 7.2 16.7 52.8 81.0 7.5 9.6 9.5 3.4 113.2 104.9 7.7 7.6 4.6 6.4 2.6 112.3 11.8 3.8 4.9 7.9 17.3 17.0 4.5 9.9 15.6 85.8 8.1 13.6 6.5 120.6 1.0 5.8 6.8 2.0 23.2 7.3 91.9 6.1 32.7 3.6 49.0 15.4 8.6 4.5 14.6 9.7 4.6 1.6 14.0 10.6 0.0 17.1 23.2 7.4 23.3 7.9 7.9 1.5 18.6 7.1 4.1 33.3 17.6 15.6 0.0 7.4 14.4 7.2 4.3 4.3 18.8 13.0 0.0 12.8 0.1 9.0 20.5 0.0 11.6 11.0 9.7 20.2 0.0 3.8 10.0 19.2 6.9 1.2 1.5 20.6 17.0 18.2 16.2 17.4 37.9 21.6 12.3 13.9 10.5 10.1 0.1 0.0 0.3 16.2 1.4 25.2 1.9 2.2 0.8 0.8 1.7 0.3 0.0 0.3 0.7 1.2 0.0 0.2 0.2 2.7 0.2 1.7 0.1 0.2 0.8 80.9 100.0 115.6 74.1 52.8 81.0 113.2 104.9 112.3 85.8 120.6 91.9 14.3 12.8 5.0 69.9 0.8 4.6 4.9 9.0 3.4 3.4 6.7 5.6 28.5 7.2 7.9 5.5 0.0 0.7 7.0 12.4 0.0 12.6 76.2 18.9 9.8 18.5 2.4 1.7 2.5 13.4 2.1 10.9 7.7 6.0 2.5 1.5 17.9 33.2 7.8 3.3 21.1 4.4 0.0 38.4 8.0 305.5 18.0 16.6 5.4 21.5 45.3 17.1 12.3 40.7 45.1 18.3 9.2 19.2 2.1 11.8 6.7 13.6 12.5 1.9 26.3 14.0 15.8 2.4 12.6 6.8 5.1 0.4 5.7 1.4 5.3 7.6 NAT14 KLP1 ENSG00000090971 "N-acetyltransferase 14 (putative)" Q8WUY8 19 55485188-55487568 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Activator, Acyltransferase, DNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 62.6;Horizontal cells: 148.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "HEK 293: 168.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047187 Approved Mitochondria NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 62: Horizontal cells - Visual perception" Mitochondria "HPA047187: AB_2679974" "unprognostic (5.96e-2)" "unprognostic (1.10e-1)" "unprognostic (2.92e-2)" "unprognostic (5.43e-2)" "unprognostic (1.32e-1)" "unprognostic (3.59e-2)" "unprognostic (1.69e-2)" "unprognostic (7.01e-2)" "unprognostic (1.94e-1)" "unprognostic (2.97e-1)" "unprognostic (9.12e-2)" "unprognostic (6.41e-2)" "prognostic unfavorable (3.61e-4)" "unprognostic (7.00e-2)" "unprognostic (6.74e-2)" "unprognostic (9.85e-2)" "unprognostic (1.58e-1)" 5.3 13.1 32.9 4.5 32.2 3.9 7.5 32.2 37.8 23.5 30.2 20.5 2.4 23.8 7.8 5.2 25.2 4.0 11.6 33.8 32.5 25.5 6.5 10.5 3.8 29.8 32.9 20.6 8.4 10.7 47.1 6.9 28.7 14.9 2.1 8.4 5.3 7.8 3.0 5.7 8.5 8.8 27.8 7.1 10.1 11.6 36.2 53.6 20.0 1.2 2.9 11.8 10.8 29.0 8.2 27.6 32.1 59.8 12.9 16.3 19.4 29.6 35.5 32.5 46.3 9.7 26.6 3.1 10.3 19.5 16.4 10.6 20.8 18.8 20.0 32.9 168.2 26.1 41.0 21.9 23.3 19.4 25.8 22.7 6.5 22.7 6.2 65.5 24.3 46.9 32.3 9.1 19.7 10.0 33.1 29.7 44.2 16.4 13.1 32.7 19.9 12.6 78.2 15.3 93.4 64.5 11.9 17.8 28.9 12.2 14.5 20.0 28.5 11.8 31.5 1.7 24.5 18.0 7.4 13.7 26.7 3.3 30.5 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.4 0.1 0.0 0.4 0.0 0.1 32.9 32.2 32.2 37.8 33.8 32.5 29.8 32.9 28.7 27.8 36.2 29.0 4.0 6.4 3.2 9.1 3.8 2.9 6.7 4.4 4.6 62.6 11.7 13.8 4.1 5.7 2.6 29.5 35.5 13.3 3.8 1.2 15.6 14.5 1.5 41.7 31.7 7.2 12.7 10.3 12.9 1.1 8.3 10.4 3.1 9.7 0.0 11.5 3.9 3.6 2.9 148.0 13.1 2.1 4.1 0.8 2.4 3.1 11.8 1.7 5.4 2.8 2.3 39.6 1.0 7.1 2.8 4.3 0.4 10.5 2.7 4.4 0.7 3.7 18.1 39.9 0.0 13.8 12.1 4.2 3.9 0.7 0.6 6.0 2.6 9.7 1.1 1.9 NAT8L "FLJ37478, Hcml3, Shati" ENSG00000185818 "N-acetyltransferase 8 like" Q8N9F0 4 2059327-2069089 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "adipose tissue: 43.5;brain: 99.0" "Cell type enhanced" "Detected in some" "Astrocytes: 126.7;Excitatory neurons: 46.0;Horizontal cells: 80.8;Inhibitory neurons: 37.6;Muller glia cells: 25.0" "Group enriched" "Detected in many" 6 "endometrial cancer: 6.2;glioma: 17.2;melanoma: 14.6;ovarian cancer: 8.0;thyroid cancer: 7.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NB-4: 20.8;SCLC-21H: 25.8;SK-MEL-30: 21.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040677 Approved Mitochondria NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 64: Astrocytes - Nervous system maintenance" Mitochondria "HPA040677: AB_2732486" "unprognostic (1.32e-2)" "unprognostic (8.62e-2)" "unprognostic (3.02e-3)" "prognostic unfavorable (1.01e-5)" "unprognostic (2.56e-1)" "unprognostic (2.63e-4)" "unprognostic (6.58e-2)" "unprognostic (1.79e-1)" "unprognostic (2.90e-2)" "unprognostic (4.54e-1)" "unprognostic (3.70e-2)" "unprognostic (7.06e-2)" "unprognostic (1.78e-3)" "unprognostic (7.24e-3)" "unprognostic (1.14e-2)" "unprognostic (2.10e-2)" "unprognostic (1.35e-2)" 43.5 0.7 56.1 0.1 46.4 0.0 1.6 42.9 99.0 0.0 0.6 0.2 0.1 0.3 1.3 0.1 0.9 0.1 0.8 45.8 29.0 5.3 0.0 0.0 0.2 52.3 46.4 0.2 2.3 0.9 1.8 0.1 57.5 1.0 0.1 3.7 2.3 1.6 5.7 1.0 0.2 0.2 33.0 0.3 0.4 9.0 88.8 0.2 0.3 2.5 0.0 0.0 0.0 38.9 0.1 9.2 4.9 10.0 0.9 0.0 5.7 0.2 0.0 0.2 0.0 4.1 0.3 0.0 1.9 0.0 1.5 0.1 11.1 0.0 0.1 0.0 13.2 0.1 2.1 6.6 1.5 14.5 6.9 0.0 0.2 0.0 0.0 1.8 0.0 3.4 11.5 0.0 0.4 6.2 0.2 20.8 14.1 0.0 4.1 0.7 2.3 0.4 0.2 0.5 25.8 8.6 6.6 0.0 21.4 0.8 0.7 8.3 0.0 0.0 3.3 0.1 5.6 0.0 0.0 0.2 0.0 6.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 56.1 46.4 42.9 99.0 45.8 29.0 52.3 46.4 57.5 33.0 88.8 38.9 0.5 0.0 0.0 126.7 0.0 0.3 0.0 0.0 0.0 14.5 1.4 2.2 2.6 0.0 0.0 1.8 6.2 0.0 5.4 0.0 0.0 4.6 1.1 1.7 0.1 0.4 1.8 0.0 46.0 0.6 0.1 0.2 0.0 1.0 0.0 21.9 0.0 0.0 0.8 80.8 37.6 0.0 0.0 0.0 0.3 3.8 0.0 0.7 10.6 17.8 0.0 25.0 0.0 23.1 15.7 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.6 0.0 0.0 0.8 0.5 1.5 0.0 0.1 0.0 0.0 0.1 0.0 0.1 NDUFA1 "CI-MWFE, MWFE" ENSG00000125356 "NADH:ubiquinone oxidoreductase subunit A1" O15239 X 119871832-119876662 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 3202.9;Distal tubular cells: 2191.3;Proximal tubular cells: 1764.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029768, HPA054359" Enhanced Approved Mitochondria,Cytosol No No "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Cytosol Mitochondria "HPA029768: AB_2673192, HPA054359: AB_2682461" "unprognostic (1.72e-1)" "unprognostic (3.00e-3)" "unprognostic (3.12e-2)" "unprognostic (1.17e-1)" "unprognostic (1.74e-1)" "unprognostic (7.34e-3)" "unprognostic (1.56e-1)" "unprognostic (8.20e-3)" "unprognostic (2.13e-1)" "unprognostic (1.02e-1)" "unprognostic (8.11e-3)" "unprognostic (4.77e-2)" "prognostic favorable (3.48e-4)" "unprognostic (1.16e-1)" "unprognostic (3.62e-2)" "unprognostic (2.67e-2)" "unprognostic (2.78e-3)" 260.4 276.7 541.8 179.3 547.2 316.3 275.0 560.4 746.6 226.5 637.9 467.4 387.4 132.4 323.9 145.0 193.2 133.0 983.7 539.2 555.3 495.1 449.6 153.8 186.7 549.0 541.6 149.3 228.5 773.9 121.4 171.4 551.2 185.8 371.3 398.6 280.0 240.2 1381.0 90.8 334.6 180.7 545.6 169.4 297.4 65.8 551.2 273.2 173.3 1367.9 219.4 228.5 90.5 549.6 436.8 561.9 342.0 365.6 466.3 317.8 423.6 346.6 395.9 297.8 368.1 326.5 377.8 385.1 509.4 431.0 514.7 416.5 555.7 392.8 354.6 492.2 751.7 380.6 1110.1 750.5 357.0 575.9 387.2 485.4 577.0 296.5 232.5 413.2 389.1 372.4 230.9 553.4 435.6 965.3 412.5 563.2 489.1 1214.3 988.4 405.3 315.2 1169.8 887.0 765.2 255.9 319.8 714.9 871.1 479.6 476.5 224.2 653.8 395.1 209.4 198.2 422.7 672.5 469.4 798.3 524.9 377.5 719.5 262.1 1064.7 680.6 822.0 486.1 726.1 468.4 560.6 540.8 516.7 745.6 447.7 435.9 523.1 851.5 468.5 815.5 809.1 675.4 780.5 541.8 547.2 560.4 746.6 539.2 555.3 549.0 541.6 551.2 545.6 551.2 549.6 251.9 160.3 188.6 10.7 261.6 213.7 251.4 991.0 194.1 156.2 268.0 322.7 3202.9 511.9 445.8 562.8 79.2 396.5 273.9 1264.2 2191.3 503.6 34.2 332.0 237.9 228.9 459.0 272.3 12.3 512.5 416.1 266.9 322.1 348.9 210.3 177.5 260.3 1022.5 661.7 82.4 14.8 907.2 581.8 413.5 350.6 43.8 294.5 329.3 570.9 14.0 492.3 364.2 277.1 8.0 16.5 506.4 1024.5 285.1 389.2 228.8 1546.3 1764.0 443.2 231.2 216.9 208.4 289.9 50.8 105.2 394.3 249.3 380.6 255.7 126.7 887.7 339.3 NDUFA4L2 "COXFA4L2, FLJ26118, NUOMS" ENSG00000185633 "NDUFA4 mitochondrial complex associated like 2" Q9NRX3 12 57234903-57240715 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 304.9" "Group enriched" "Detected in many" 4 "Muller glia cells: 627.0;Sertoli cells: 1130.7;Smooth muscle cells: 525.6" "Cancer enriched" "Detected in all" 5 "renal cancer: 356.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 7 "AN3-CA: 133.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055323, HPA078265" Uncertain Approved Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria "HPA055323: , HPA078265: " "unprognostic (1.25e-1)" "unprognostic (1.60e-1)" "unprognostic (2.11e-3)" "unprognostic (3.23e-3)" "unprognostic (5.06e-2)" "unprognostic (1.22e-2)" "unprognostic (2.25e-2)" "unprognostic (3.53e-1)" "unprognostic (6.67e-2)" "unprognostic (5.79e-2)" "unprognostic (2.13e-1)" "unprognostic (2.89e-1)" "prognostic unfavorable (1.37e-5)" "unprognostic (9.10e-3)" "unprognostic (1.31e-1)" "unprognostic (6.41e-2)" "unprognostic (2.74e-2)" 85.6 14.0 41.6 6.8 40.1 0.2 55.1 41.4 61.5 109.3 36.8 17.4 5.8 20.7 2.4 304.9 15.5 17.1 180.1 40.3 41.1 47.6 20.9 62.6 5.8 43.0 42.7 14.0 14.5 12.1 30.9 71.7 48.8 27.3 1.9 29.4 55.8 9.8 43.8 206.9 14.2 7.5 38.9 74.1 18.0 8.7 43.5 3.2 54.5 29.2 4.8 27.7 183.5 45.4 0.9 1.3 0.3 133.9 5.4 3.1 0.4 2.1 1.5 0.6 1.3 0.0 1.5 5.5 5.6 2.1 0.1 1.2 0.7 1.0 0.0 3.0 0.2 0.6 0.3 0.1 18.6 4.1 2.0 12.0 2.5 0.2 4.7 0.9 0.0 7.6 0.5 7.2 0.4 2.7 1.1 0.2 0.3 0.6 2.4 2.1 1.0 11.0 0.1 0.1 7.1 2.5 0.2 0.3 4.7 0.1 1.5 14.5 0.6 1.2 0.1 1.1 0.7 10.0 3.5 2.5 4.9 9.8 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 41.6 40.1 41.4 61.5 40.3 41.1 43.0 42.7 48.8 38.9 43.5 45.4 156.0 0.0 0.5 2.6 2.6 151.2 0.9 89.2 6.8 30.6 2.6 5.8 1.2 0.0 24.8 0.0 18.8 1.0 0.9 0.1 0.0 1.6 1.7 0.4 3.0 91.8 0.0 0.0 2.2 0.0 1.5 21.5 4.6 0.3 8.9 0.1 2.9 1.3 1.9 11.8 3.0 0.2 54.9 0.0 28.9 3.0 3.1 2.0 30.2 18.7 1.0 627.0 0.0 0.5 0.4 4.7 0.0 2.2 1.4 2.0 0.1 0.3 6.2 25.7 1130.7 13.0 525.6 12.3 5.5 20.3 161.4 1.1 1.9 2.5 0.2 1.4 NDUFA9 "CI-39k, COQ11, NDUFS2L, SDR22E1" ENSG00000139180 "NADH:ubiquinone oxidoreductase subunit A9" Q16795 12 4649095-4694317 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 617.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042268, HPA073212" Supported Approved Nucleoplasm,Mitochondria No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria Nucleoplasm "HPA042268: AB_2677922, HPA073212: AB_2686581" "unprognostic (2.26e-1)" "unprognostic (7.85e-3)" "unprognostic (3.67e-2)" "unprognostic (1.84e-1)" "unprognostic (2.41e-2)" "unprognostic (7.58e-2)" "unprognostic (9.64e-3)" "unprognostic (3.02e-1)" "unprognostic (2.06e-1)" "unprognostic (1.25e-1)" "unprognostic (3.45e-2)" "unprognostic (1.16e-1)" "prognostic favorable (2.57e-7)" "unprognostic (7.80e-2)" "unprognostic (1.71e-1)" "unprognostic (1.93e-2)" "prognostic favorable (5.75e-4)" 19.6 29.2 25.6 14.8 26.5 35.3 19.1 29.1 38.5 18.4 29.5 41.1 30.6 20.4 14.7 30.9 17.5 6.1 116.7 26.1 25.7 43.4 49.4 18.0 11.8 26.0 25.5 14.7 24.2 34.2 21.9 10.2 26.7 21.4 31.2 20.1 24.3 11.1 110.3 24.1 31.0 12.7 25.7 23.7 31.6 14.3 26.4 18.1 19.3 110.6 14.5 21.2 19.8 27.0 29.8 52.5 25.3 33.9 18.3 18.1 73.1 22.1 22.4 41.9 31.6 114.4 58.0 33.2 11.6 24.2 47.5 48.9 37.1 32.9 27.0 64.8 65.3 32.5 51.0 88.1 40.0 48.0 33.8 23.3 31.2 28.7 38.6 26.0 32.0 46.8 23.1 60.8 31.5 57.6 48.5 55.1 65.5 55.6 43.2 67.4 37.5 34.5 59.2 66.6 18.2 20.6 27.9 74.4 41.9 54.4 15.4 45.4 22.2 31.8 64.7 29.3 52.3 11.9 15.1 57.1 33.2 29.4 35.7 75.9 134.3 53.3 99.2 165.1 102.1 148.3 102.4 109.3 161.9 110.0 88.9 91.1 11.8 107.5 133.5 168.0 143.6 265.0 25.6 26.5 29.1 38.5 26.1 25.7 26.0 25.5 26.7 25.7 26.4 27.0 37.5 28.9 32.1 26.1 45.2 48.6 63.7 199.3 21.6 48.6 40.1 37.0 185.1 45.8 99.4 64.4 58.4 111.1 45.7 89.4 166.3 130.0 112.2 29.3 29.6 46.4 47.4 36.0 21.0 131.3 118.7 38.5 35.2 26.0 57.7 36.6 34.6 78.5 114.7 33.7 26.3 125.4 140.4 35.6 31.8 617.2 28.3 41.8 55.2 15.9 60.0 48.2 49.4 27.2 20.1 108.0 83.5 36.9 50.8 40.5 108.5 163.2 74.9 67.8 19.7 32.0 54.8 30.6 31.3 38.5 47.2 99.9 43.4 66.3 147.7 69.4 NDUFAF8 C17orf89 ENSG00000224877 "NADH:ubiquinone oxidoreductase complex assembly factor 8" A1L188 17 81239305-81241310 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 264.3" "Cell type enhanced" "Detected in many" "Breast glandular cells: 130.5;Breast myoepithelial cells: 162.6;Distal tubular cells: 279.7;Proximal tubular cells: 337.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA057732 Uncertain Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA057732: AB_2683513" "unprognostic (4.33e-3)" "unprognostic (2.01e-1)" "unprognostic (1.04e-1)" "unprognostic (4.62e-2)" "unprognostic (1.97e-1)" "unprognostic (9.32e-2)" "unprognostic (3.06e-1)" "unprognostic (4.21e-2)" "unprognostic (2.60e-1)" "unprognostic (2.71e-2)" "unprognostic (2.40e-3)" "unprognostic (2.31e-1)" "prognostic unfavorable (1.70e-6)" "unprognostic (5.74e-2)" "unprognostic (2.00e-1)" "unprognostic (1.54e-1)" "unprognostic (1.05e-2)" 47.8 65.1 164.7 28.2 167.7 37.0 40.3 159.5 264.3 32.9 156.0 49.5 21.8 30.4 33.6 45.9 32.0 9.8 110.7 161.5 158.1 68.6 79.1 27.5 26.5 160.1 160.0 33.6 56.3 40.1 54.2 14.5 159.1 44.1 29.4 24.0 36.7 20.2 144.5 33.0 31.6 21.8 161.1 40.4 45.5 30.7 166.1 30.8 38.7 93.0 32.1 45.2 31.6 159.9 142.1 199.9 73.2 72.1 80.4 84.9 79.0 122.1 49.3 82.0 47.1 102.5 60.0 131.6 60.2 86.2 68.2 69.2 69.2 117.4 97.8 33.3 437.1 99.8 222.2 233.3 84.7 139.2 60.8 113.5 140.2 59.3 124.8 87.8 133.0 103.6 132.5 77.3 106.8 130.4 194.6 145.1 41.1 114.6 288.2 121.6 104.8 96.7 89.5 96.1 84.1 107.7 100.5 82.2 126.1 107.2 115.1 127.7 81.5 101.4 154.8 73.2 123.2 110.2 41.1 124.0 91.7 72.8 79.9 41.2 80.1 69.1 73.4 67.1 73.4 103.6 80.4 88.9 82.0 87.6 96.4 94.4 10.3 78.0 76.2 138.0 87.3 77.5 164.7 167.7 159.5 264.3 161.5 158.1 160.1 160.0 159.1 161.1 166.1 159.9 47.9 19.2 17.3 0.0 24.9 0.0 0.0 0.0 0.0 0.0 130.5 162.6 0.0 0.0 9.3 101.2 0.0 120.5 41.0 0.0 279.7 98.1 0.0 59.8 75.1 21.6 0.0 0.0 0.0 124.6 99.0 32.0 0.0 48.1 1.3 73.5 0.0 0.0 129.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.0 0.0 0.0 51.1 0.0 0.0 0.0 0.0 117.4 0.0 0.0 10.6 0.0 0.0 337.8 3.6 0.0 0.0 0.0 40.5 0.0 0.0 0.0 0.0 45.6 23.1 96.8 0.0 0.0 NDUFB11 "ESSS, Np15, NP17.3" ENSG00000147123 "NADH:ubiquinone oxidoreductase subunit B11" Q9NX14 X 47142216-47145038 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Cardiomyopathy, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 717.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030367 Supported Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA030367: AB_10603882" "unprognostic (2.20e-1)" "unprognostic (6.77e-3)" "unprognostic (1.39e-1)" "unprognostic (1.33e-1)" "unprognostic (9.80e-2)" "unprognostic (8.84e-2)" "unprognostic (3.31e-2)" "unprognostic (2.05e-1)" "unprognostic (5.18e-2)" "unprognostic (1.24e-2)" "unprognostic (1.69e-2)" "unprognostic (2.19e-1)" "unprognostic (6.58e-2)" "unprognostic (3.27e-1)" "unprognostic (2.34e-1)" "unprognostic (1.69e-1)" "unprognostic (8.46e-3)" 71.1 133.8 136.0 73.2 141.2 133.2 89.8 147.7 170.6 74.6 158.5 112.5 96.7 54.4 104.6 95.2 84.1 46.2 251.4 140.3 142.3 108.9 164.4 62.2 90.3 144.7 139.0 58.5 158.2 122.9 92.7 62.4 142.0 73.9 98.2 59.2 128.2 79.2 717.0 76.1 96.1 72.2 138.3 74.5 97.8 26.8 146.3 97.8 95.6 378.4 106.3 68.0 66.5 139.3 173.5 297.9 198.7 242.4 173.6 166.1 221.1 125.2 180.5 231.5 224.4 292.6 224.2 218.5 101.8 163.4 222.3 216.2 267.0 157.3 162.0 212.4 663.1 129.5 371.2 271.3 184.7 203.2 188.2 176.9 140.0 191.2 126.8 137.8 193.9 286.8 158.6 282.6 139.3 437.2 269.1 622.5 308.5 219.2 517.2 259.7 210.9 513.6 254.0 210.1 391.2 283.1 231.9 289.2 198.8 259.8 418.2 279.7 130.3 152.7 190.5 239.1 149.0 244.0 270.0 258.5 155.0 138.4 204.2 255.4 410.3 188.6 294.2 306.5 362.1 541.7 408.9 342.6 491.6 470.0 454.3 359.3 84.9 279.7 233.8 636.5 476.3 626.1 136.0 141.2 147.7 170.6 140.3 142.3 144.7 139.0 142.0 138.3 146.3 139.3 154.0 105.8 132.5 16.6 270.9 259.5 252.1 514.5 267.5 89.2 343.7 520.1 236.6 265.9 284.7 290.6 37.5 456.9 227.6 400.0 583.0 314.9 5.2 193.4 229.7 165.6 330.7 246.3 10.2 369.1 429.2 192.1 200.8 267.1 194.1 219.2 203.8 657.2 391.0 55.5 16.7 495.1 333.7 321.7 290.9 16.3 181.7 229.1 265.1 12.2 336.9 238.9 183.4 14.1 25.3 291.8 391.2 176.4 445.1 258.6 360.1 756.8 180.9 109.8 164.3 157.6 248.9 16.8 36.9 358.0 290.5 450.9 228.9 342.6 447.4 334.9 NDUFB2 "AGGG, CI-AGGG" ENSG00000090266 "NADH:ubiquinone oxidoreductase subunit B2" O95178 7 140690777-140722790 "Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 3191.4;Distal tubular cells: 1997.6;Proximal tubular cells: 2437.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051377 Approved Uncertain Nucleoplasm,Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Mitochondria "HPA051377: AB_2681460" "unprognostic (1.17e-2)" "unprognostic (4.63e-2)" "unprognostic (2.25e-1)" "unprognostic (4.83e-2)" "unprognostic (2.29e-2)" "unprognostic (2.07e-1)" "unprognostic (3.20e-2)" "unprognostic (3.30e-2)" "unprognostic (8.30e-2)" "unprognostic (1.95e-3)" "unprognostic (4.35e-3)" "unprognostic (1.23e-1)" "prognostic favorable (7.60e-7)" "unprognostic (2.05e-1)" "unprognostic (1.07e-1)" "unprognostic (8.28e-2)" "unprognostic (1.55e-1)" 187.2 225.3 347.4 123.4 363.9 143.1 159.9 377.3 441.6 142.0 374.0 239.9 166.0 153.4 171.5 196.9 129.6 141.8 847.4 343.6 369.1 420.0 281.2 140.1 164.8 359.0 355.8 108.0 159.4 362.6 182.3 105.9 361.1 152.0 183.0 175.9 197.6 152.3 834.7 152.0 161.1 154.8 369.8 155.1 216.4 125.5 378.3 162.3 350.5 913.1 134.0 186.6 145.5 377.6 322.5 497.0 182.1 400.9 291.9 297.5 259.9 227.0 207.6 241.4 229.1 389.7 317.3 243.1 331.7 289.9 441.7 155.4 167.0 333.4 194.1 399.5 556.9 179.1 442.3 461.3 230.0 279.2 231.0 331.6 287.5 227.0 138.2 201.3 368.1 338.8 311.2 289.9 343.2 945.8 448.2 719.4 424.0 670.0 585.0 251.1 174.6 569.4 492.0 634.2 369.0 359.3 310.4 513.8 281.0 205.7 222.9 315.7 295.2 307.0 179.2 365.6 401.5 267.6 567.2 457.2 469.0 447.7 395.8 713.9 1045.5 503.4 779.4 1117.0 673.3 1009.8 755.0 768.2 1161.9 787.8 800.5 793.7 85.6 823.9 1037.9 926.9 772.0 1795.1 347.4 363.9 377.3 441.6 343.6 369.1 359.0 355.8 361.1 369.8 378.3 377.6 262.7 189.1 238.4 25.5 191.1 226.5 289.3 693.4 128.1 181.9 458.3 514.8 3191.4 351.8 398.1 673.1 98.0 555.4 275.3 776.2 1997.6 373.9 901.2 294.2 298.4 283.6 428.7 143.7 19.9 314.4 466.6 327.2 307.3 366.3 280.6 212.8 205.6 1079.3 710.8 139.7 22.7 576.3 687.7 280.3 337.3 246.9 222.7 336.5 434.0 13.1 356.7 367.2 465.5 19.6 42.3 279.4 647.9 243.8 210.7 440.1 867.3 2437.9 370.2 284.1 197.2 199.2 372.0 77.0 208.6 321.9 280.6 515.0 241.7 288.6 669.6 435.8 NDUFC1 KFYI ENSG00000109390 "NADH:ubiquinone oxidoreductase subunit C1" O43677 4 139266880-139302551 "Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "heart muscle: 83.5;skeletal muscle: 268.3;tongue: 158.5" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1840.3;Distal tubular cells: 1136.7;Proximal tubular cells: 1449.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044556, HPA062427" Enhanced Approved Mitochondria No No "Cluster 24: B-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA044556: AB_10794402, HPA062427: " "unprognostic (6.07e-2)" "unprognostic (4.61e-3)" "unprognostic (1.76e-2)" "prognostic favorable (8.23e-5)" "unprognostic (7.11e-2)" "unprognostic (1.74e-1)" "unprognostic (1.23e-1)" "unprognostic (1.40e-1)" "unprognostic (7.62e-2)" "unprognostic (3.60e-2)" "unprognostic (3.58e-2)" "unprognostic (1.17e-2)" "prognostic favorable (9.96e-4)" "unprognostic (2.33e-1)" "unprognostic (1.07e-1)" "unprognostic (1.66e-1)" "prognostic favorable (7.25e-4)" 9.5 15.3 19.9 8.0 20.4 9.1 11.0 22.4 28.6 7.4 21.3 18.6 23.8 8.1 14.3 10.5 10.5 5.4 83.5 19.6 20.8 26.7 24.1 8.8 10.1 20.3 21.0 10.0 14.8 22.9 15.8 5.9 21.6 9.7 19.0 23.5 18.9 14.4 268.3 13.2 18.6 7.4 19.5 10.4 17.0 12.7 20.5 8.6 14.8 158.5 11.0 8.6 7.9 22.4 21.4 5.9 19.2 30.8 17.7 22.7 20.5 20.1 13.1 11.1 10.4 13.1 23.7 7.7 7.7 15.5 14.9 10.5 38.6 18.2 15.0 13.0 13.5 11.9 13.5 23.0 18.1 11.2 10.1 24.5 18.2 14.4 21.6 16.8 17.5 17.8 25.3 33.8 11.0 17.8 17.8 32.1 16.3 44.1 11.7 14.9 10.6 52.6 24.6 14.2 14.6 14.7 13.8 23.2 10.5 15.6 23.7 23.2 8.1 24.2 6.4 13.0 13.5 23.2 49.5 18.5 18.9 26.7 13.8 26.2 10.1 13.1 8.5 10.3 11.6 7.1 11.7 11.5 8.9 15.9 10.5 11.4 3.0 10.1 14.2 16.2 18.2 10.8 19.9 20.4 22.4 28.6 19.6 20.8 20.3 21.0 21.6 19.5 20.5 22.4 201.8 89.8 145.7 15.7 95.8 140.2 173.3 402.7 185.0 120.4 240.3 349.6 1840.3 221.6 240.1 439.6 33.3 147.4 71.7 343.0 1136.7 270.3 409.9 333.5 115.5 162.7 221.4 175.2 10.9 336.9 166.2 176.9 158.0 196.8 73.3 151.2 133.5 432.9 225.1 119.5 14.3 340.5 276.7 102.0 65.7 70.9 169.3 115.6 266.8 6.5 185.5 446.6 79.3 8.0 13.3 265.3 355.8 206.5 155.6 173.7 471.7 1449.6 297.1 139.1 98.6 159.3 184.4 439.0 197.4 290.1 179.3 118.1 83.5 224.7 343.7 176.0 NDUFS8 "CI-23k, TYKY" ENSG00000110717 "NADH:ubiquinone oxidoreductase core subunit S8" O00217 11 68030617-68036644 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 833.5;Late spermatids: 797.2;Proximal tubular cells: 927.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018524, HPA067429" Enhanced Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA018524: AB_1854355, HPA067429: " "unprognostic (2.90e-1)" "unprognostic (1.41e-3)" "unprognostic (2.41e-1)" "unprognostic (5.20e-2)" "unprognostic (1.37e-1)" "unprognostic (1.30e-3)" "unprognostic (1.36e-1)" "unprognostic (7.75e-2)" "unprognostic (3.15e-1)" "unprognostic (1.77e-2)" "unprognostic (3.81e-2)" "unprognostic (1.81e-1)" "prognostic favorable (3.27e-8)" "unprognostic (2.29e-1)" "unprognostic (1.38e-1)" "unprognostic (2.60e-2)" "unprognostic (9.45e-2)" 99.2 308.4 141.2 38.8 153.2 56.2 87.7 157.2 180.4 73.2 172.3 142.0 81.4 89.2 27.2 115.3 81.3 29.1 468.2 144.2 152.0 188.6 152.0 73.1 42.2 149.6 144.9 68.2 97.7 74.6 130.6 33.6 145.8 118.2 36.7 49.5 96.2 66.7 406.4 93.0 84.4 39.0 142.2 76.9 137.8 104.7 154.0 40.3 101.8 275.5 30.1 94.4 76.0 150.2 152.9 366.4 94.6 137.0 70.9 63.5 132.4 102.3 88.5 155.6 118.9 338.4 159.6 118.4 186.8 85.9 134.6 181.2 108.8 128.4 53.1 139.4 264.9 107.2 217.1 186.3 171.8 99.1 112.1 80.5 126.5 111.1 124.8 82.0 106.2 159.9 110.3 121.1 99.2 358.6 219.2 216.9 125.2 377.7 308.0 154.4 95.9 384.9 192.8 123.3 125.5 102.2 75.7 171.7 392.3 66.5 245.6 105.9 84.1 155.6 133.9 224.8 148.8 165.2 188.5 99.7 252.3 121.8 111.2 84.7 220.1 124.0 182.4 232.0 170.1 183.3 154.6 165.5 309.4 156.3 146.2 164.2 20.7 309.6 131.7 324.3 202.2 232.4 141.2 153.2 157.2 180.4 144.2 152.0 149.6 144.9 145.8 142.2 154.0 150.2 88.7 89.8 90.1 18.6 92.3 85.4 95.5 284.3 104.7 83.4 147.2 156.7 301.9 143.0 164.9 213.3 54.2 279.6 97.8 301.0 833.5 200.8 225.7 101.1 74.8 85.3 205.0 149.8 13.6 199.3 165.9 109.6 147.3 79.7 95.8 156.5 73.5 231.7 276.6 50.5 19.3 277.2 240.1 124.1 108.0 797.2 100.6 128.7 163.7 13.1 187.4 143.6 128.8 12.1 15.4 173.7 194.9 108.0 157.8 118.6 337.1 927.8 120.8 118.7 59.2 81.2 208.6 105.9 72.7 209.7 116.2 172.4 102.7 278.7 318.2 139.1 NDUFV2 CI-24k ENSG00000178127 "NADH:ubiquinone oxidoreductase core subunit V2" P19404 18 9102630-9134345 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 606.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003404, HPA077896" Supported Approved Nucleoplasm,Mitochondria,Cytosol No No 7600 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Mitochondria "Nucleoplasm, Cytosol" "HPA003404: AB_1079466, HPA077896: AB_2686866" "unprognostic (1.18e-1)" "unprognostic (3.89e-2)" "unprognostic (2.89e-1)" "unprognostic (8.22e-2)" "unprognostic (1.32e-2)" "unprognostic (6.72e-3)" "unprognostic (1.36e-2)" "unprognostic (1.18e-1)" "unprognostic (6.72e-3)" "unprognostic (1.32e-3)" "unprognostic (2.39e-1)" "unprognostic (6.84e-2)" "unprognostic (1.70e-1)" "unprognostic (5.51e-2)" "unprognostic (1.31e-1)" "unprognostic (6.56e-2)" "unprognostic (1.95e-3)" 97.4 171.6 94.3 69.2 97.4 149.8 101.7 106.8 139.7 63.9 106.0 124.2 102.3 69.7 91.1 142.6 64.0 68.7 419.3 96.7 106.0 180.7 404.2 88.6 105.0 105.9 104.4 52.4 111.6 136.7 72.1 73.7 105.9 88.5 119.8 129.9 97.4 72.4 606.9 94.7 100.5 80.6 103.7 86.4 133.8 79.6 102.7 90.2 72.7 538.3 105.1 122.1 76.5 104.6 136.5 139.8 159.1 148.4 116.6 164.0 133.4 165.4 266.5 217.7 205.5 265.1 109.4 209.4 149.5 158.6 200.3 66.9 157.5 175.5 208.8 104.6 136.6 133.0 135.3 364.8 133.6 373.8 159.2 139.2 144.3 134.9 146.2 156.8 239.3 184.3 216.5 644.0 204.6 171.6 263.5 328.9 131.4 750.5 172.3 124.5 118.2 794.2 354.3 218.7 167.0 122.3 164.6 188.0 220.3 113.6 174.2 282.8 145.8 273.4 194.3 198.8 223.0 180.4 292.3 237.1 195.4 166.0 181.0 250.8 161.8 194.2 118.1 196.1 148.3 237.6 176.9 140.5 237.9 201.1 153.5 142.7 76.0 124.2 187.9 315.1 231.9 231.8 94.3 97.4 106.8 139.7 96.7 106.0 105.9 104.4 105.9 103.7 102.7 104.6 107.3 80.1 145.8 17.6 143.1 148.0 319.0 629.4 159.4 101.2 165.0 167.3 69.9 178.7 339.5 150.8 87.6 344.1 146.6 211.0 876.5 415.2 271.5 160.3 108.2 117.3 106.5 165.4 32.9 531.4 323.3 122.0 144.3 183.9 120.3 109.7 96.4 351.5 313.5 94.2 37.3 201.7 480.1 115.7 267.1 186.2 122.1 170.2 231.3 17.8 293.2 167.1 96.8 32.2 46.5 530.3 201.2 102.0 244.9 554.3 349.9 810.6 293.4 184.2 105.2 124.0 196.3 217.4 175.0 226.5 147.6 289.4 165.7 266.7 227.3 469.0 NF1 ENSG00000196712 "Neurofibromin 1" P21359 17 31094927-31382116 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "GTPase activation" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 254.0;Excitatory neurons: 325.3;Inhibitory neurons: 412.5;Oligodendrocyte precursor cells: 428.2;Oligodendrocytes: 317.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045502 Uncertain Approved Mitochondria No No "Cluster 20: T-cells - T-cell receptor" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA045502: AB_2679352" "unprognostic (6.69e-2)" "unprognostic (8.73e-2)" "unprognostic (8.26e-2)" "unprognostic (1.76e-2)" "unprognostic (2.06e-2)" "unprognostic (2.79e-2)" "unprognostic (1.38e-1)" "unprognostic (1.07e-1)" "unprognostic (1.11e-1)" "unprognostic (1.30e-2)" "unprognostic (3.14e-2)" "unprognostic (3.88e-2)" "unprognostic (1.00e-2)" "unprognostic (2.19e-1)" "unprognostic (1.53e-1)" "unprognostic (1.40e-1)" "unprognostic (3.70e-1)" 7.4 8.4 8.9 7.1 10.7 3.4 11.5 13.2 12.2 10.0 1.6 8.5 6.8 10.2 10.0 6.1 9.0 8.0 11.3 9.7 11.7 12.0 9.4 7.3 7.7 11.7 9.2 13.5 10.4 15.9 7.8 12.4 9.1 9.5 8.8 20.9 9.1 9.5 8.1 7.4 7.5 8.7 8.2 7.1 8.2 10.0 11.8 13.5 19.5 10.6 7.8 10.4 6.8 14.4 15.8 20.3 24.2 13.1 20.1 25.8 12.2 13.4 24.1 19.5 21.8 18.4 10.5 15.2 3.8 25.1 22.9 26.8 22.2 18.7 32.6 7.5 14.1 13.4 18.8 9.5 14.2 24.4 10.6 20.7 11.8 20.8 25.1 21.8 9.5 15.7 19.8 14.8 18.8 12.4 20.4 8.8 7.1 9.7 6.8 15.8 36.8 12.3 14.7 22.5 10.0 14.9 25.4 8.3 13.8 16.8 25.0 15.3 14.1 15.3 21.5 18.8 5.1 13.2 6.9 16.3 12.6 10.0 16.2 4.4 0.3 0.6 1.5 0.1 1.0 1.4 2.8 2.5 0.4 1.2 2.0 2.0 0.7 0.7 0.3 0.4 5.9 0.6 8.9 10.7 13.2 12.2 9.7 11.7 11.7 9.2 9.1 8.2 11.8 14.4 30.9 32.1 31.1 254.0 18.3 38.6 48.1 38.9 31.9 62.7 33.7 24.9 43.9 41.5 29.8 40.5 137.6 57.5 23.8 37.8 23.5 27.1 210.4 27.4 39.4 35.8 19.8 9.7 325.3 22.5 26.6 39.1 39.3 45.8 10.8 44.0 33.2 35.7 22.5 70.7 412.5 24.3 38.7 27.6 34.1 94.6 37.3 28.2 21.4 215.5 20.9 47.5 21.6 428.2 317.4 33.3 43.0 50.4 30.8 54.2 32.1 28.6 36.9 62.8 46.0 51.9 43.3 30.5 28.7 19.8 34.0 49.3 19.8 36.1 27.4 64.5 NGDN "C14orf120, CANu1, DKFZP564O092, LCP5, lpd-2, NGD" ENSG00000129460 Neuroguidin Q8NEJ9 14 23469689-23509862 "Predicted intracellular proteins" "Translation regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000944 Approved Approved Nucleoplasm,Nucleoli,Mitochondria Yes No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Mitochondria" Nucleoplasm "HPA000944: AB_1079483" "unprognostic (2.63e-3)" "unprognostic (7.65e-2)" "unprognostic (2.84e-1)" "unprognostic (4.16e-3)" "unprognostic (1.51e-2)" "unprognostic (3.14e-2)" "unprognostic (8.87e-2)" "unprognostic (1.72e-3)" "unprognostic (5.64e-2)" "unprognostic (3.87e-3)" "unprognostic (7.10e-2)" "unprognostic (1.65e-1)" "unprognostic (6.36e-2)" "unprognostic (9.83e-2)" "unprognostic (2.29e-2)" "unprognostic (2.58e-1)" "unprognostic (1.70e-1)" 32.2 26.4 25.6 23.3 28.4 64.4 40.3 30.5 37.7 30.5 25.0 30.1 23.4 34.7 32.5 26.2 32.0 17.6 23.7 25.9 26.6 31.3 32.9 24.2 35.3 27.1 27.0 39.6 25.7 33.3 20.8 29.2 27.7 24.8 29.0 25.2 24.6 26.6 53.4 35.2 26.8 31.4 27.7 28.6 27.0 28.6 26.9 37.5 28.4 39.2 36.8 32.3 27.7 31.7 37.6 73.1 54.5 51.5 52.0 37.3 72.1 48.6 50.7 101.3 81.4 72.1 66.8 92.6 35.0 44.7 71.1 63.7 109.0 60.1 118.7 61.8 57.3 83.2 44.1 229.3 70.5 110.4 56.9 46.5 75.0 79.9 94.4 39.6 52.2 69.5 93.6 64.1 50.4 88.8 82.3 86.0 69.5 84.8 97.1 67.1 65.6 47.9 65.7 70.4 55.6 62.8 57.6 68.3 83.8 55.0 42.2 70.4 39.8 47.8 57.3 45.1 71.3 79.4 148.7 133.3 20.6 56.1 52.2 67.0 62.3 58.5 88.0 71.8 93.5 129.0 94.6 89.9 74.8 107.7 121.3 95.5 19.1 109.5 71.7 79.1 116.1 93.3 25.6 28.4 30.5 37.7 25.9 26.6 27.1 27.0 27.7 27.7 26.9 31.7 33.8 35.3 29.2 2.9 52.1 70.6 63.8 78.2 72.8 23.2 25.5 31.2 20.2 21.5 46.8 27.6 16.7 59.3 45.3 19.9 33.2 38.6 7.2 24.3 25.9 36.5 24.6 35.1 7.5 36.0 43.3 34.4 16.3 27.5 45.0 23.2 25.4 21.4 29.8 25.2 6.8 22.7 28.5 19.2 39.0 6.9 35.1 21.1 32.0 9.4 34.3 26.8 46.4 4.0 11.0 31.1 22.8 28.2 30.4 42.9 25.8 35.5 36.6 28.6 19.7 51.5 36.0 68.7 64.2 39.6 67.6 57.2 47.6 20.5 27.2 49.5 NHLRC4 ENSG00000257108 "NHL repeat containing 4" P0CG21 16 567005-569495 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 11.7;kidney: 10.5" "Cell type enhanced" "Detected in some" "Collecting duct cells: 23.9;Endometrial ciliated cells: 23.3;Erythroid cells: 11.8;Leydig cells: 8.1;Respiratory ciliated cells: 18.1;Theca cells: 12.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "eosinophil: 2.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 3.3;HMC-1: 9.6;REH: 2.6;RPMI-8226: 4.3" "Low region specificity" "Detected in single" HPA077301 Approved Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 3: HMC-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" Mitochondria "HPA077301: " "unprognostic (7.95e-2)" "unprognostic (5.87e-2)" "unprognostic (4.28e-3)" "unprognostic (2.53e-2)" "unprognostic (1.08e-1)" "unprognostic (5.95e-3)" "unprognostic (2.21e-1)" "unprognostic (2.48e-1)" "unprognostic (2.28e-1)" "unprognostic (3.34e-1)" "unprognostic (2.20e-3)" "unprognostic (1.19e-2)" "unprognostic (1.16e-2)" "unprognostic (5.16e-3)" "unprognostic (1.25e-1)" "unprognostic (1.67e-2)" "unprognostic (1.60e-1)" 0.8 5.4 0.6 0.7 0.5 2.9 1.2 0.8 0.5 1.8 2.1 0.9 1.0 1.1 2.1 0.3 11.7 0.9 0.9 0.7 1.0 10.5 0.2 2.0 1.9 2.8 3.3 3.0 0.2 3.2 1.1 0.6 1.7 1.4 0.2 0.0 2.2 2.4 0.5 0.3 1.5 0.3 2.3 3.8 0.6 2.7 0.8 2.4 0.4 0.2 0.6 0.7 0.6 0.6 0.0 0.0 0.4 0.0 0.0 0.2 0.1 0.0 0.6 0.1 0.1 0.1 0.1 0.5 0.4 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.1 3.3 0.0 0.8 0.7 0.2 9.6 1.9 0.0 0.1 0.2 0.0 0.2 0.6 1.0 1.1 0.0 0.0 0.3 2.5 0.2 0.0 0.0 2.6 0.0 4.3 0.2 0.1 0.0 0.9 0.0 0.0 0.3 0.0 0.4 0.5 0.5 0.0 0.0 0.0 0.0 1.5 1.4 0.7 0.0 0.1 0.2 0.0 0.2 2.3 0.1 0.0 0.2 0.4 0.5 0.2 0.2 0.2 0.5 0.3 0.0 0.3 0.1 1.7 0.5 0.3 0.6 0.5 0.8 0.5 0.7 1.0 2.8 3.3 1.7 2.3 0.8 0.6 1.6 0.0 0.0 0.3 1.2 0.0 0.5 0.8 0.6 0.1 1.9 1.4 0.2 0.0 2.2 23.9 0.0 0.2 1.8 0.1 0.0 0.0 0.0 23.3 1.1 1.0 0.0 11.8 0.1 0.2 0.0 2.3 0.0 1.0 0.0 0.4 1.1 0.0 1.7 0.0 0.5 0.2 2.0 0.6 0.9 0.4 8.1 0.5 0.0 1.0 0.2 1.5 1.0 0.0 0.0 0.0 0.0 4.5 0.9 0.3 0.3 0.1 18.1 0.1 6.6 0.1 2.0 0.1 0.1 0.0 0.1 0.0 0.7 12.7 0.2 0.3 NLGN2 KIAA1366 ENSG00000169992 "Neuroligin 2" Q8NFZ4 17 7404874-7419860 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 32.7;Horizontal cells: 57.2;Oligodendrocyte precursor cells: 45.8;Sertoli cells: 32.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 42.2" "Low region specificity" "Detected in all" "HPA055321, HPA069278" Enhanced Approved Mitochondria NA NA 14000 "Cluster 72: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" Mitochondria "HPA055321: AB_2682783, HPA069278: AB_2686105" "unprognostic (1.31e-1)" "unprognostic (1.87e-2)" "unprognostic (4.35e-3)" "unprognostic (2.58e-1)" "unprognostic (1.12e-1)" "unprognostic (9.79e-3)" "unprognostic (2.92e-1)" "unprognostic (1.56e-1)" "unprognostic (6.50e-2)" "unprognostic (2.24e-2)" "unprognostic (5.58e-3)" "unprognostic (1.23e-2)" "prognostic unfavorable (3.44e-4)" "unprognostic (1.69e-1)" "unprognostic (2.85e-1)" "unprognostic (5.50e-3)" "unprognostic (1.81e-2)" 25.0 18.1 25.6 4.8 26.0 0.4 21.2 13.5 25.3 61.9 0.0 36.4 1.5 57.9 7.5 10.2 46.1 7.7 18.2 23.7 18.6 16.6 9.3 16.7 2.7 18.1 15.2 66.6 9.4 7.6 23.7 3.8 13.9 29.7 2.2 15.5 13.6 9.0 11.7 14.8 16.6 12.3 12.1 16.9 16.3 6.7 20.9 0.8 14.2 2.4 1.8 31.2 32.4 19.0 7.1 9.8 42.2 24.4 12.6 18.0 1.0 11.6 18.2 19.4 17.9 2.2 2.4 0.1 5.5 16.4 11.4 3.9 7.9 4.9 10.0 10.8 7.9 3.1 9.6 1.6 6.3 3.1 10.4 14.1 3.8 15.9 2.4 29.1 6.5 3.9 2.9 5.6 7.9 6.6 1.4 3.1 7.2 0.4 4.7 12.9 5.0 1.4 5.6 1.5 0.6 17.0 5.3 2.5 3.0 8.3 6.9 0.4 9.0 16.6 20.6 10.5 5.7 6.4 2.2 1.2 17.3 2.8 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.6 26.0 13.5 25.3 23.7 18.6 18.1 15.2 13.9 12.1 20.9 19.0 5.4 0.0 2.6 25.8 0.5 4.7 3.1 3.3 7.4 32.7 5.6 5.2 11.0 5.7 1.0 0.0 8.4 0.4 3.4 0.1 0.0 2.7 2.0 1.5 25.3 6.8 0.0 0.0 23.5 0.4 6.3 11.5 0.5 2.3 0.0 5.8 6.1 3.2 1.0 57.2 24.8 0.3 0.0 0.8 1.8 2.9 17.1 0.7 1.8 5.6 0.6 22.3 0.0 45.8 13.6 1.6 0.0 22.2 0.3 3.0 0.1 1.3 0.8 16.8 32.9 10.8 10.7 0.5 1.1 1.2 3.8 0.8 1.7 4.3 0.3 1.2 NLN "AGTBP, KIAA1226" ENSG00000123213 Neurolysin Q9BYT8 5 65722205-65871725 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 52.8;Excitatory neurons: 58.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.6;intermediate monocyte: 3.4;myeloid DC: 2.2;non-classical monocyte: 2.3" "Group enriched" "Detected in many" 5 "dendritic cells: 2.2;monocytes: 3.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031862 Approved Approved Mitochondria Yes No 64000 "Cluster 7: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA031862: AB_10600827" "unprognostic (5.91e-3)" "unprognostic (4.52e-2)" "unprognostic (1.34e-3)" "unprognostic (4.37e-2)" "unprognostic (3.85e-1)" "unprognostic (1.45e-2)" "unprognostic (7.29e-3)" "unprognostic (3.24e-2)" "unprognostic (3.19e-1)" "unprognostic (3.58e-1)" "prognostic unfavorable (7.51e-4)" "unprognostic (1.27e-1)" "prognostic favorable (5.58e-7)" "unprognostic (1.52e-2)" "unprognostic (1.98e-1)" "unprognostic (1.29e-1)" "unprognostic (6.18e-3)" 2.2 1.0 3.8 2.4 3.9 1.5 3.7 2.9 5.3 1.8 1.6 3.6 1.1 2.7 2.4 2.5 1.5 1.2 2.6 3.8 3.6 3.9 9.9 1.7 1.7 3.9 3.4 1.8 2.5 1.5 0.9 2.4 4.0 2.6 3.2 2.5 1.9 1.1 8.9 2.8 2.7 2.7 3.3 1.3 4.0 1.1 3.9 0.9 2.7 6.5 2.0 2.7 1.5 4.8 13.3 12.5 7.2 12.0 9.0 15.3 14.5 13.1 5.5 7.6 8.2 7.2 7.7 18.8 16.1 15.8 15.1 10.3 9.5 20.2 13.1 5.6 6.4 5.2 8.7 18.5 7.7 12.0 3.0 11.7 10.8 10.5 12.4 6.3 21.7 8.3 11.4 3.9 16.5 10.2 8.3 10.8 22.2 6.7 3.6 9.6 15.3 29.9 12.6 5.9 22.3 11.5 10.6 10.7 11.0 19.4 12.9 14.1 12.5 5.0 5.9 7.4 10.0 3.3 7.1 8.2 7.7 23.2 7.7 0.1 2.6 0.1 0.1 3.4 0.1 0.4 0.2 0.1 2.2 0.4 0.3 0.2 0.3 0.5 2.3 0.1 0.0 1.0 3.8 3.9 2.9 5.3 3.8 3.6 3.9 3.4 4.0 3.3 3.9 4.8 5.9 6.4 2.8 19.6 4.0 5.7 9.0 6.2 8.6 2.4 10.1 8.9 14.5 7.2 8.5 12.9 4.2 5.3 0.6 52.8 5.9 17.8 0.3 7.4 12.9 8.3 1.8 9.0 58.9 14.5 14.0 7.1 20.4 20.9 15.2 16.2 4.6 32.4 28.8 5.0 32.2 5.8 6.1 22.9 8.9 0.4 4.4 13.5 1.8 5.6 17.9 13.1 2.1 22.6 44.5 30.2 35.9 2.2 4.9 16.5 32.3 22.4 3.1 4.7 0.0 19.7 8.1 2.1 5.2 15.3 5.3 2.9 2.3 15.8 8.2 6.1 NLRP4 "CLR19.5, CT58, FLJ32126, NALP4, PAN2, PYPAF4, RNH2" ENSG00000160505 "NLR family pyrin domain containing 4" Q96MN2 19 55836540-55881855 "Predicted intracellular proteins" "Inflammatory response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "lymphoid tissue: 5.0;testis: 7.0" "Cell type enhanced" "Detected in some" "Early spermatids: 17.6;Late spermatids: 5.1;Spermatogonia: 3.3" "Cancer enriched" "Detected in single" 7 "testis cancer: 1.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "Daudi: 82.3" "Not detected" "Not detected" HPA062128 Approved Mitochondria NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Mitochondria "HPA062128: " "unprognostic (2.48e-1)" "unprognostic (7.01e-2)" "unprognostic (4.21e-2)" "unprognostic (1.34e-2)" "unprognostic (3.11e-1)" "unprognostic (1.81e-1)" "unprognostic (2.36e-3)" "unprognostic (3.72e-2)" "unprognostic (2.36e-1)" "unprognostic (3.89e-1)" "unprognostic (2.02e-1)" "unprognostic (1.17e-1)" "unprognostic (2.71e-2)" 0.1 0.0 0.5 0.6 0.6 0.0 0.0 0.7 1.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.0 1.6 0.8 0.6 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 7.0 0.7 0.1 0.0 0.0 5.0 0.0 0.0 1.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 82.3 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.6 0.4 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.7 1.0 0.7 0.5 0.8 0.6 0.8 0.6 0.7 1.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.1 5.1 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NNT ENSG00000112992 "Nicotinamide nucleotide transhydrogenase" Q13423 5 43602692-43707405 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Translocase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 239.1;tongue: 384.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 344.3;Hepatocytes: 314.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004829, CAB004975" Enhanced Approved Mitochondria,Cytosol NA NA 110000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria Cytosol "CAB004975: AB_425908, HPA004829: AB_1079495" "unprognostic (1.51e-1)" "unprognostic (1.07e-1)" "unprognostic (3.33e-2)" "unprognostic (4.81e-2)" "unprognostic (5.02e-2)" "unprognostic (1.81e-1)" "unprognostic (4.04e-2)" "unprognostic (1.96e-3)" "unprognostic (2.20e-2)" "unprognostic (3.98e-2)" "unprognostic (1.65e-1)" "unprognostic (8.33e-2)" "prognostic favorable (1.22e-15)" "unprognostic (8.24e-2)" "unprognostic (1.11e-1)" "unprognostic (2.76e-2)" "unprognostic (2.58e-1)" 26.0 16.5 12.8 11.8 16.0 15.0 13.7 11.2 21.7 16.4 34.9 25.9 17.2 11.0 16.7 16.8 10.7 15.0 137.7 16.1 11.5 57.0 116.4 13.2 16.5 10.3 12.0 10.1 17.8 55.6 9.6 12.7 9.5 18.3 27.8 12.9 26.6 18.2 239.1 10.4 16.1 20.6 9.3 11.5 31.2 6.2 15.8 26.8 31.1 384.0 17.2 17.3 9.3 15.1 15.4 12.6 30.5 59.6 44.0 50.3 9.9 17.5 39.8 24.8 20.8 19.0 30.4 18.5 21.5 43.9 22.3 16.6 120.5 5.4 27.4 31.1 33.6 24.0 70.7 23.8 27.5 50.2 43.1 37.9 17.5 16.3 18.6 42.6 56.3 22.7 21.4 81.3 60.0 15.1 55.8 35.8 6.4 0.1 15.2 54.7 73.8 70.8 58.0 15.5 44.2 37.7 62.9 1.4 46.7 6.9 47.7 58.3 23.2 29.5 28.3 12.0 8.3 36.1 45.1 26.5 7.1 68.8 22.1 12.5 18.2 16.0 16.7 23.0 17.1 12.0 17.1 15.5 32.0 12.0 15.5 14.7 2.9 23.2 24.7 9.1 22.2 19.3 12.8 16.0 11.2 21.7 16.1 11.5 10.3 12.0 9.5 9.3 15.8 15.1 12.0 54.5 37.8 60.7 19.6 11.5 9.5 19.0 13.1 17.9 9.6 6.3 344.3 38.6 27.0 27.6 35.5 8.7 20.4 34.4 27.4 14.4 16.7 18.5 16.6 19.2 19.9 34.9 124.8 10.7 2.3 27.2 23.9 25.1 25.2 26.8 21.0 314.3 25.0 6.7 110.6 22.6 20.3 40.6 11.9 4.6 14.9 19.8 14.2 45.9 25.9 12.5 35.0 77.9 63.4 9.5 16.7 19.2 20.0 11.7 23.6 21.7 18.1 12.8 0.0 14.0 20.1 4.0 1.4 17.6 8.1 2.1 20.9 18.8 28.9 9.9 NOD1 "CARD4, CLR7.1, NLRC1" ENSG00000106100 "Nucleotide binding oligomerization domain containing 1" Q9Y239 7 30424527-30478784 "Human disease related genes, Predicted intracellular proteins" "Apoptosis, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 19.3;Microglial cells: 26.2" "Cancer enhanced" "Detected in all" "thyroid cancer: 11.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA074367 Approved Mitochondria NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Mitochondria "HPA074367: AB_2686683" "unprognostic (2.58e-1)" "unprognostic (1.56e-2)" "unprognostic (9.73e-2)" "unprognostic (8.09e-3)" "unprognostic (2.07e-2)" "unprognostic (1.70e-1)" "unprognostic (1.01e-3)" "unprognostic (6.63e-2)" "unprognostic (2.26e-1)" "unprognostic (2.74e-1)" "unprognostic (8.78e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (6.68e-4)" "unprognostic (6.62e-2)" "unprognostic (1.46e-1)" "prognostic favorable (1.95e-4)" "unprognostic (2.64e-1)" 10.6 2.9 3.0 8.8 3.2 6.8 9.5 2.5 2.6 5.3 4.6 5.3 2.2 6.1 2.6 4.7 6.5 5.4 7.3 2.4 3.2 3.9 2.2 11.9 6.1 7.6 4.9 10.3 1.8 2.7 2.9 12.2 4.7 4.0 4.3 0.6 6.2 3.2 4.0 5.9 5.4 7.3 3.6 11.1 4.8 1.9 5.6 3.5 10.8 4.0 5.0 7.3 5.0 2.8 4.8 2.5 3.5 10.5 2.2 10.3 5.3 3.3 2.3 5.5 7.0 2.2 5.7 6.9 3.8 4.2 6.1 11.2 3.5 5.8 3.7 3.6 3.0 9.7 7.7 2.2 2.8 4.3 7.0 9.6 2.5 3.5 3.0 4.9 18.3 10.1 5.2 2.4 5.0 2.8 6.2 7.7 4.1 5.3 4.5 7.4 4.0 6.3 1.8 3.8 0.6 12.4 4.2 10.7 3.7 4.8 3.6 9.6 7.7 4.8 7.6 6.0 4.5 2.2 8.0 0.3 3.5 15.1 5.1 13.7 3.7 13.5 8.1 5.0 8.9 7.5 5.5 5.3 3.3 10.9 4.9 4.0 2.8 8.5 6.6 8.0 4.8 2.6 3.0 3.2 2.5 2.6 2.4 3.2 7.6 4.9 4.7 3.6 5.6 2.8 19.3 3.2 15.1 7.2 6.6 0.8 0.5 1.0 5.2 2.4 2.9 2.9 4.9 1.5 5.0 5.5 0.0 5.0 6.7 4.5 0.0 1.3 0.2 4.4 1.7 12.0 0.0 3.4 5.3 2.1 2.3 8.2 1.1 4.6 2.5 7.8 13.6 1.3 4.6 0.0 1.4 5.5 2.0 3.1 3.7 0.0 0.6 4.3 5.4 26.2 4.0 0.6 6.2 2.5 1.1 1.7 1.7 1.9 3.1 0.2 1.6 0.5 2.9 0.2 0.0 2.5 5.6 0.0 0.6 5.4 1.8 1.5 5.3 1.0 5.6 0.8 NSD3 "FLJ20353, KMT3F, WHISTLE, WHSC1L1" ENSG00000147548 "Nuclear receptor binding SET domain protein 3" Q9BZ95 8 38269704-38382272 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 173.8;Syncytiotrophoblasts: 130.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005659, CAB013721, HPA018893" Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 37: B-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" Mitochondria Nucleoplasm "CAB013721: , HPA005659: AB_1080596, HPA018893: AB_1858833" "unprognostic (6.21e-2)" "unprognostic (3.73e-2)" "unprognostic (2.18e-2)" "unprognostic (4.12e-1)" "unprognostic (2.25e-1)" "unprognostic (1.53e-2)" "unprognostic (4.35e-2)" "unprognostic (1.97e-2)" "unprognostic (2.49e-1)" "unprognostic (5.72e-2)" "prognostic unfavorable (7.48e-4)" "unprognostic (5.06e-2)" "unprognostic (5.60e-3)" "unprognostic (6.69e-2)" "unprognostic (4.04e-1)" "unprognostic (1.05e-2)" "unprognostic (1.60e-2)" 22.4 14.4 10.0 24.8 13.7 60.2 23.4 28.4 20.5 24.0 0.7 22.4 24.1 22.9 17.4 22.9 23.5 24.5 13.7 12.8 22.3 20.0 16.6 20.6 35.3 3.1 4.8 36.4 20.1 24.8 17.3 33.5 5.3 20.9 26.6 23.3 19.9 24.3 14.4 19.8 26.7 19.8 0.1 26.9 29.0 14.4 10.4 38.3 27.6 16.0 31.0 23.3 23.1 18.7 62.1 34.9 58.7 39.9 40.3 46.0 43.4 50.8 55.9 43.1 49.7 18.8 33.6 73.5 45.5 35.0 41.7 36.4 47.0 40.6 61.0 29.4 27.6 93.6 28.6 22.1 41.2 41.7 32.5 24.9 40.4 39.0 78.6 40.3 50.1 79.8 67.9 47.4 41.5 22.3 122.8 35.4 40.0 48.0 16.4 55.5 64.1 23.4 30.3 47.3 33.0 44.6 41.4 35.8 35.3 37.5 45.1 31.4 48.3 44.5 46.0 67.0 30.3 41.9 53.8 69.2 37.6 41.3 33.0 37.4 11.8 21.9 17.2 5.6 11.0 43.1 25.5 15.5 9.3 60.7 31.9 13.7 57.9 19.6 3.6 12.6 43.4 7.3 10.0 13.7 28.4 20.5 12.8 22.3 3.1 4.8 5.3 0.1 10.4 18.7 75.1 67.3 57.3 0.0 57.8 0.0 0.0 0.0 0.0 0.0 73.4 69.1 0.0 0.0 30.3 51.5 0.0 101.6 101.9 0.0 23.5 73.0 0.0 109.1 81.3 28.0 0.0 0.0 0.0 61.0 173.8 33.1 0.0 97.5 8.8 99.7 0.0 0.0 44.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.1 0.0 0.0 49.7 0.0 0.0 0.0 0.0 64.7 0.0 0.0 48.9 0.0 0.0 31.7 34.2 0.0 0.0 0.0 35.8 0.0 0.0 0.0 0.0 130.8 55.6 81.7 0.0 0.0 NT5DC3 "FLJ11266, TU12B1-TY" ENSG00000111696 "5'-nucleotidase domain containing 3" Q86UY8 12 103770453-103841234 "Metabolic proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 80.5" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 41.2;Excitatory neurons: 36.6;Oligodendrocyte precursor cells: 29.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTERT-HME1: 22.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041634 Approved Mitochondria,Cytosol "Secreted - unknown location" NA NA "Cluster 30: Non-specific - Translation" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" Mitochondria Cytosol "HPA041634: AB_10795597" "unprognostic (2.61e-2)" "unprognostic (1.16e-1)" "unprognostic (7.30e-2)" "unprognostic (2.72e-1)" "unprognostic (8.45e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (4.31e-4)" "unprognostic (1.57e-1)" "unprognostic (2.19e-1)" "unprognostic (2.45e-2)" "unprognostic (5.43e-2)" "unprognostic (2.95e-1)" "prognostic unfavorable (5.72e-6)" "unprognostic (8.60e-3)" "unprognostic (7.42e-2)" "unprognostic (2.14e-1)" "prognostic unfavorable (8.11e-4)" 2.9 4.0 14.2 1.9 12.0 17.5 3.3 0.0 13.3 9.3 0.0 80.5 1.0 23.1 5.0 5.2 3.7 1.4 1.9 23.3 7.8 2.0 5.0 2.8 1.3 1.5 1.8 2.9 3.5 0.8 4.5 1.5 1.4 7.5 7.7 2.3 4.1 5.4 7.8 2.5 4.7 6.8 1.2 1.6 6.6 3.1 8.9 0.6 1.9 3.3 1.2 21.7 5.7 4.8 3.6 6.5 3.6 4.2 5.1 4.0 6.8 5.9 3.5 4.1 2.6 4.4 0.9 6.1 1.1 7.0 4.5 4.1 5.2 11.7 5.9 4.5 4.2 7.6 2.5 5.2 2.8 4.1 1.9 3.5 2.5 5.3 22.7 8.3 2.4 3.0 12.2 3.0 9.2 3.3 3.6 6.6 4.5 5.2 6.9 4.9 6.3 2.3 6.5 2.4 4.9 2.0 4.9 5.4 7.1 3.3 3.1 3.8 3.2 4.0 4.8 5.5 11.9 2.7 3.5 4.4 3.8 6.2 6.0 0.4 0.5 0.0 0.6 0.6 1.2 1.3 0.9 0.5 1.5 1.4 0.7 0.6 0.9 0.6 0.4 1.9 0.2 0.3 14.2 12.0 0.0 13.3 23.3 7.8 1.5 1.8 1.4 1.2 8.9 4.8 1.4 0.0 2.3 3.9 2.7 4.5 21.9 3.0 21.6 2.0 5.6 7.4 3.8 2.8 2.1 1.8 0.0 5.2 2.7 5.8 0.0 2.1 12.1 14.0 11.9 1.7 41.2 1.3 36.6 2.0 4.7 3.8 7.7 19.4 0.0 3.7 0.7 5.3 1.8 10.1 24.4 11.4 10.2 4.1 6.5 10.5 5.0 2.8 0.0 6.5 2.9 0.8 1.0 29.1 2.7 2.7 2.2 8.2 2.7 13.0 1.1 2.1 6.9 5.0 0.0 5.6 5.7 0.4 3.1 9.0 4.4 4.1 2.5 4.1 9.2 9.8 NYAP2 KIAA1486 ENSG00000144460 "Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2" Q9P242 2 225399710-225654018 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 9 "brain: 8.7" "Group enriched" "Detected in some" 8 "Excitatory neurons: 136.8;Inhibitory neurons: 238.3" "Not detected" "Not detected" "Region enhanced" "Detected in many" "midbrain: 8.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SiHa: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045531, HPA056945" Uncertain Approved Mitochondria,Cytosol NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 20: HeLa - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria Cytosol "HPA045531: AB_10960749, HPA056945: " "unprognostic (2.49e-1)" "unprognostic (3.34e-1)" "unprognostic (1.24e-1)" "unprognostic (2.63e-1)" "unprognostic (2.35e-1)" "unprognostic (6.13e-3)" "unprognostic (3.33e-1)" "unprognostic (2.08e-1)" "unprognostic (1.32e-8)" "unprognostic (9.83e-2)" "unprognostic (2.92e-1)" "unprognostic (6.46e-2)" "unprognostic (1.27e-1)" 0.0 0.0 0.8 0.0 1.6 0.0 0.0 0.7 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.7 1.9 0.0 0.0 0.2 0.0 0.1 8.7 0.0 0.0 0.0 0.3 0.0 2.0 0.0 0.0 0.9 0.0 0.0 0.4 0.0 0.0 0.0 2.9 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.6 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 1.6 0.7 2.7 1.7 1.9 0.1 8.7 2.0 2.9 2.4 0.0 0.1 0.0 2.3 4.9 0.1 1.3 1.7 0.0 0.0 21.8 0.2 0.0 0.5 0.0 0.6 0.0 2.1 0.2 0.2 0.1 0.0 0.3 0.6 0.2 0.1 0.4 0.0 0.0 136.8 1.2 0.3 0.5 0.0 0.2 0.0 0.0 0.0 0.3 0.1 0.0 238.3 0.0 0.0 0.8 1.8 0.8 0.0 0.6 0.0 1.0 0.2 0.5 0.0 1.5 2.5 1.2 0.0 0.0 0.1 1.1 0.0 0.1 0.0 1.5 0.0 3.6 0.5 0.2 0.1 0.0 1.0 0.1 0.5 0.0 0.0 0.8 OCIAD1 "Asrij, FLJ20455, OCIA, TPA018" ENSG00000109180 "OCIA domain containing 1" Q9NX40 4 48805212-48861817 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044803 Approved Approved Mitochondria NA NA 21000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Mitochondria "HPA044803: AB_10961287" "unprognostic (8.18e-2)" "unprognostic (1.60e-2)" "unprognostic (4.82e-2)" "unprognostic (7.39e-2)" "unprognostic (1.69e-1)" "unprognostic (4.17e-2)" "unprognostic (2.53e-1)" "unprognostic (1.60e-1)" "unprognostic (4.10e-1)" "unprognostic (2.83e-3)" "unprognostic (1.34e-1)" "unprognostic (5.42e-2)" "unprognostic (1.47e-3)" "unprognostic (9.23e-2)" "unprognostic (2.86e-1)" "unprognostic (1.56e-1)" "unprognostic (1.16e-2)" 129.5 184.0 161.1 99.4 170.6 107.7 153.9 154.6 212.9 150.3 173.5 161.1 155.8 138.0 192.2 118.1 167.2 124.6 219.3 177.3 177.0 238.1 326.5 124.1 127.3 161.1 153.1 159.1 156.1 248.7 109.9 118.4 157.6 145.9 159.9 143.7 161.9 148.1 255.0 107.1 134.6 133.3 163.1 105.1 141.3 91.0 165.8 133.6 239.4 255.9 133.9 136.3 72.3 172.6 165.2 118.2 231.7 162.8 230.8 283.0 178.6 253.1 393.8 261.1 311.3 110.6 473.2 190.4 241.5 238.0 311.4 141.7 229.4 250.4 296.2 149.4 152.7 293.4 105.7 88.1 336.5 309.1 300.9 292.0 353.5 208.3 258.4 315.4 270.0 173.9 339.8 104.1 300.0 107.7 261.4 287.6 195.2 211.7 110.4 169.6 216.9 203.1 502.9 154.5 139.8 261.0 120.4 101.1 306.5 179.8 212.8 271.5 196.9 176.1 200.7 120.7 333.1 256.3 380.4 283.1 223.2 251.0 220.2 47.8 60.2 76.5 62.6 68.0 90.8 74.1 73.1 79.2 75.4 64.9 90.2 80.5 48.3 95.4 86.5 85.2 68.5 73.5 161.1 170.6 154.6 212.9 177.3 177.0 161.1 153.1 157.6 163.1 165.8 172.6 176.7 160.3 124.5 85.8 107.1 79.7 111.3 243.3 102.4 126.6 96.7 119.6 152.3 102.9 169.4 121.4 66.7 170.5 103.1 140.0 137.0 140.0 34.3 147.3 120.5 120.2 130.1 89.8 125.1 128.3 168.8 124.4 84.1 110.5 141.8 102.6 118.9 167.3 152.7 89.2 137.2 131.3 124.1 94.0 77.2 35.5 132.3 106.1 87.2 76.8 107.2 206.1 121.5 106.1 158.1 130.7 122.5 139.2 115.3 104.2 164.1 178.9 151.2 111.6 124.9 121.3 112.7 188.3 88.3 94.1 75.9 164.7 109.8 197.2 142.7 100.4 OMA1 "FLJ33782, MPRP-1, YKR087C, ZMPOMA1" ENSG00000162600 "OMA1 zinc metallopeptidase" Q96E52 1 58415384-58546802 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 106.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055120 Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Mitochondria" "HPA055120: AB_2682702" "prognostic favorable (1.63e-4)" "unprognostic (2.67e-2)" "prognostic favorable (7.70e-4)" "unprognostic (1.60e-3)" "unprognostic (1.61e-1)" "unprognostic (9.57e-2)" "unprognostic (3.94e-3)" "prognostic favorable (8.52e-4)" "unprognostic (8.22e-3)" "unprognostic (6.91e-2)" "unprognostic (4.10e-2)" "unprognostic (1.40e-1)" "unprognostic (9.54e-3)" "unprognostic (2.52e-2)" "unprognostic (3.93e-2)" "unprognostic (1.74e-2)" "unprognostic (5.24e-3)" 11.4 18.7 15.1 14.0 22.8 12.8 19.7 23.1 14.9 16.7 14.9 20.8 14.9 13.5 17.8 13.3 19.4 15.1 19.8 13.0 19.5 28.4 31.1 11.9 23.4 18.8 17.9 13.5 17.9 18.1 10.4 11.5 21.1 20.8 20.0 20.5 19.5 16.7 28.2 12.8 14.2 12.4 15.6 20.2 17.3 8.2 18.3 20.2 20.1 29.9 21.5 14.8 10.5 27.3 31.2 13.0 8.3 7.9 41.7 39.0 24.6 12.7 13.9 10.9 13.7 4.0 18.7 69.8 26.3 13.1 37.8 31.2 31.1 31.3 13.3 55.1 17.9 22.0 10.4 16.1 20.3 54.3 14.7 37.3 33.6 10.4 22.4 24.1 9.3 34.3 42.7 20.1 29.2 19.5 18.0 19.4 12.4 47.4 28.5 22.1 27.7 29.1 23.6 20.5 8.7 4.3 26.0 41.9 37.6 38.4 19.5 20.1 5.4 5.6 10.8 27.8 13.5 16.3 23.4 46.2 16.8 42.2 14.1 20.1 14.4 32.1 19.4 24.1 25.6 35.6 23.7 23.1 15.4 35.0 33.9 31.5 17.2 30.9 35.1 8.2 23.6 15.9 15.1 22.8 23.1 14.9 13.0 19.5 18.8 17.9 21.1 15.6 18.3 27.3 8.4 19.2 11.5 37.9 25.7 6.0 18.2 35.6 13.6 7.8 15.0 12.3 27.2 8.6 33.0 25.8 12.5 22.9 14.4 8.4 25.4 11.2 5.8 31.6 10.8 6.3 6.0 15.6 18.3 5.5 10.0 12.0 5.6 18.4 6.3 10.9 6.4 18.7 15.8 1.7 31.7 17.7 36.7 10.1 9.7 12.7 9.9 12.9 7.2 29.0 11.3 10.9 15.5 52.8 106.5 3.8 10.9 8.6 16.8 12.3 8.5 32.4 63.1 20.5 6.6 12.0 8.6 14.3 13.6 17.3 6.8 18.3 20.7 17.1 14.6 17.1 OTULIN "FAM105B, FLJ34884" ENSG00000154124 "OTU deubiquitinase with linear linkage specificity" Q96BN8 5 14664664-14699850 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Immunity, Innate immunity, Ubl conjugation pathway, Wnt signaling pathway" "Hydrolase, Protease, Thiol protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 26.8" "Cell type enhanced" "Detected in many" "dendritic cells: 70.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051074 Uncertain Approved "Plasma membrane,Mitochondria" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 20: HeLa - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" Mitochondria "Plasma membrane" "HPA051074: AB_2681334" "unprognostic (4.81e-3)" "unprognostic (1.11e-1)" "unprognostic (4.00e-2)" "unprognostic (1.19e-2)" "unprognostic (7.48e-2)" "unprognostic (1.91e-2)" "unprognostic (7.94e-3)" "unprognostic (1.43e-1)" "unprognostic (2.48e-2)" "unprognostic (9.55e-2)" "unprognostic (1.02e-1)" "unprognostic (7.13e-2)" "prognostic unfavorable (2.59e-7)" "unprognostic (2.92e-2)" "unprognostic (2.28e-2)" "unprognostic (1.60e-1)" "unprognostic (5.02e-2)" 5.0 3.9 4.8 9.6 6.3 26.8 4.6 5.9 4.9 5.5 6.2 4.7 7.6 3.6 2.6 8.0 3.5 4.7 6.7 4.9 5.0 4.4 12.3 6.4 12.5 6.6 5.6 4.8 6.8 3.8 3.6 6.5 6.4 6.3 4.6 4.6 5.7 3.3 5.2 11.8 5.8 4.8 5.6 7.1 4.3 7.1 5.8 11.2 4.1 5.5 13.5 5.7 6.9 7.1 10.0 11.5 11.2 12.8 10.0 10.3 12.3 9.8 6.9 13.8 10.2 15.4 7.2 18.0 18.9 6.4 19.9 11.1 14.1 12.9 9.2 31.1 11.6 12.9 36.3 8.3 8.8 12.4 21.2 6.0 15.2 11.3 9.4 7.6 11.8 14.9 13.0 27.8 10.0 6.1 12.4 10.6 6.9 10.5 12.0 18.8 10.0 7.1 8.9 10.1 5.1 8.3 35.1 7.8 7.6 13.5 8.5 14.1 11.1 17.8 20.0 13.4 13.2 12.4 20.6 20.3 10.1 23.2 9.3 0.2 0.6 1.1 0.3 0.7 1.0 0.3 0.8 1.1 1.0 1.6 0.5 1.3 0.7 0.3 1.1 0.8 1.7 0.3 4.8 6.3 5.9 4.9 4.9 5.0 6.6 5.6 6.4 5.6 5.8 7.1 20.3 3.2 11.5 23.5 24.6 0.0 23.2 0.0 26.2 11.9 12.8 11.7 15.0 10.0 4.3 5.5 14.6 15.1 70.6 21.1 7.9 5.5 9.4 20.6 28.1 13.3 9.5 13.7 18.5 5.8 10.3 10.1 16.8 24.0 10.2 14.0 6.4 36.9 13.9 8.4 19.5 15.7 0.0 18.9 0.0 4.2 10.5 25.0 0.0 38.4 17.1 10.4 26.8 16.6 31.7 8.0 13.3 6.4 38.5 25.9 14.1 15.1 5.1 31.4 0.0 11.5 10.2 29.7 28.8 23.7 0.0 14.2 35.8 7.6 15.6 23.1 PACS2 "KIAA0602, PACS1L" ENSG00000179364 "Phosphofurin acidic cluster sorting protein 2" Q86VP3 14 105300563-105398147 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Apoptosis, Host-virus interaction" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 136.6;skeletal muscle: 98.5" "Cell type enhanced" "Detected in all" "Horizontal cells: 97.6;Oligodendrocytes: 169.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077892 Approved Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA077892: AB_2686865" "unprognostic (4.31e-2)" "unprognostic (2.61e-1)" "unprognostic (4.53e-2)" "unprognostic (1.24e-1)" "unprognostic (3.09e-2)" "unprognostic (4.08e-2)" "prognostic unfavorable (3.11e-5)" "unprognostic (1.18e-2)" "unprognostic (1.37e-1)" "unprognostic (1.90e-1)" "prognostic favorable (2.95e-4)" "unprognostic (1.49e-1)" "prognostic favorable (1.56e-4)" "unprognostic (2.08e-1)" "unprognostic (3.80e-1)" "unprognostic (2.58e-1)" "unprognostic (1.30e-1)" 22.4 16.1 48.4 10.6 101.5 9.0 18.7 104.4 61.3 18.1 4.7 24.6 10.9 21.0 5.4 11.2 19.0 11.2 23.8 43.2 58.0 12.4 6.9 16.1 8.5 136.6 110.6 20.0 28.8 11.7 21.6 8.8 119.6 15.0 6.6 12.2 16.3 11.5 98.5 12.6 14.2 10.0 80.8 16.0 17.4 19.8 106.1 9.4 14.1 46.1 5.5 19.3 14.1 126.8 17.5 23.8 21.9 20.7 21.5 20.6 25.9 13.0 15.0 11.0 9.6 10.4 32.5 19.0 21.5 20.0 14.1 19.7 13.5 18.7 7.9 23.7 11.0 8.7 10.0 15.6 28.1 7.1 15.0 24.1 17.5 7.7 17.7 13.9 20.1 18.9 5.4 17.2 9.7 54.9 12.1 9.5 8.5 22.1 19.4 26.5 13.3 12.1 9.3 39.7 49.0 25.8 12.4 11.1 19.4 13.7 28.1 13.2 30.8 16.2 7.2 25.6 13.1 22.3 15.6 7.2 24.6 12.8 16.1 0.0 0.6 0.1 0.3 1.1 0.6 0.0 0.3 0.4 1.1 0.2 0.1 0.4 0.1 1.0 1.9 2.3 0.8 0.4 48.4 101.5 104.4 61.3 43.2 58.0 136.6 110.6 119.6 80.8 106.1 126.8 28.3 9.6 14.7 41.1 3.3 9.1 7.5 7.1 8.0 30.5 15.1 14.4 21.4 8.6 12.6 5.5 12.5 4.3 15.1 21.5 13.7 13.9 77.1 13.8 15.7 21.1 13.1 4.2 29.7 23.0 3.2 15.5 20.4 18.3 1.3 28.8 19.2 10.8 17.6 97.6 41.0 14.6 8.2 15.7 23.0 78.7 17.4 17.1 26.6 30.9 8.4 17.0 7.2 23.1 169.3 14.2 12.6 16.6 7.1 9.0 19.3 12.3 7.7 23.4 6.6 20.6 14.2 18.3 14.6 8.1 8.4 3.4 8.0 30.6 19.5 8.0 PAGE1 "CT16.3, GAGE-9, GAGEB1, PAGE-1" ENSG00000068985 "PAGE family member 1" O75459 X 49687447-49695984 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 151 "testis: 17.2" "Group enriched" "Detected in some" 5 "Spermatocytes: 166.9;Spermatogonia: 206.5" "Group enriched" "Detected in many" 4 "liver cancer: 10.5;melanoma: 5.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "A-431: 188.0;Karpas-707: 139.8;U-266/84: 230.7" HPA003473 Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Mitochondria" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoli fibrillar center" "Nucleoplasm, Mitochondria" "HPA003473: AB_1079558" "unprognostic (3.00e-1)" "unprognostic (1.99e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 188.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 17.7 0.0 0.0 0.0 0.0 0.4 0.0 0.1 1.1 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.7 139.8 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 26.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.4 0.3 0.2 0.3 1.6 0.6 2.8 230.7 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 32.9 0.0 0.0 166.9 206.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PAGE5 "CT16.1, CT16.2, PAGE-5" ENSG00000158639 "PAGE family member 5" Q96GU1 X 55220346-55224108 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 25 "testis: 26.5" "Group enriched" "Detected in some" 7 "Spermatocytes: 131.0;Spermatogonia: 158.8" "Group enriched" "Detected in many" 6 "liver cancer: 5.4;melanoma: 11.8;testis cancer: 6.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 1.9" "Lineage enriched" "Detected in single" 13 "T-cells: 1.9" "Group enriched" "Detected in some" 170 "Karpas-707: 437.8;U-266/84: 992.7" "HPA052619, HPA055869" Supported Approved Mitochondria NA NA "Cluster 13: T-cells - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Mitochondria "HPA052619: AB_2681887, HPA055869: " "unprognostic (4.03e-1)" "unprognostic (4.51e-2)" "unprognostic (7.86e-4)" "unprognostic (1.39e-2)" "unprognostic (7.21e-2)" "unprognostic (1.06e-4)" "unprognostic (2.29e-1)" "unprognostic (1.94e-1)" "unprognostic (3.44e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.1 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.3 26.5 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.7 0.1 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 437.8 0.0 0.0 1.2 0.0 0.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.4 0.0 0.0 0.5 1.3 1.6 4.2 992.7 0.5 0.1 0.0 0.7 0.0 0.0 0.0 0.3 0.0 1.9 0.1 1.6 0.7 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.1 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 19.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.0 0.3 11.9 2.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.5 0.1 0.0 6.6 0.0 0.1 131.0 158.8 0.0 0.1 0.0 1.4 0.0 0.0 0.1 PAPSS2 ATPSK2 ENSG00000198682 "3'-phosphoadenosine 5'-phosphosulfate synthase 2" O95340 10 87659613-87747705 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Multifunctional enzyme, Nucleotidyltransferase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 135.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 240.4;Distal enterocytes: 202.4;Hepatocytes: 111.5;Proximal enterocytes: 181.3;Theca cells: 96.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 4.0;myeloid DC: 2.1;non-classical monocyte: 7.7" "Group enriched" "Detected in many" 7 "dendritic cells: 2.1;monocytes: 7.7" "Cell line enhanced" "Detected in many" "BJ: 189.8;fHDF/TERT166: 473.2;HHSteC: 196.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071224, HPA075267" Enhanced Approved Mitochondria No No 16000 "Cluster 7: Monocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" Mitochondria "HPA071224: AB_2686366, HPA075267: " "unprognostic (3.98e-3)" "unprognostic (7.06e-2)" "unprognostic (4.95e-3)" "unprognostic (1.02e-1)" "unprognostic (2.67e-1)" "unprognostic (1.61e-2)" "unprognostic (4.96e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.33e-6)" "unprognostic (3.50e-2)" "prognostic favorable (6.58e-4)" "unprognostic (1.14e-1)" "unprognostic (4.90e-2)" "unprognostic (6.72e-3)" "unprognostic (1.73e-1)" "prognostic unfavorable (3.21e-5)" "unprognostic (3.46e-3)" 33.3 135.2 6.3 26.6 7.0 2.0 20.9 6.2 9.5 17.8 6.2 79.9 29.5 8.5 3.1 10.2 12.4 20.7 11.6 5.8 6.2 23.8 77.0 70.4 11.0 6.9 6.6 27.5 26.1 2.1 3.0 58.5 7.5 6.7 64.3 2.3 16.4 3.4 4.7 3.5 61.8 16.7 6.8 8.5 9.2 11.7 8.0 3.0 21.3 8.7 14.8 16.6 11.5 7.2 19.9 20.0 6.4 0.3 129.4 164.8 0.3 189.8 157.7 110.4 79.9 1.0 4.1 0.1 9.8 473.2 3.5 8.5 13.9 13.3 125.2 0.2 10.0 8.8 13.4 0.1 196.5 0.2 3.8 58.7 0.3 63.7 5.2 135.6 94.2 1.4 0.0 89.4 79.2 74.1 0.1 0.7 7.4 4.8 24.1 0.4 0.1 0.4 117.5 8.7 0.9 1.6 92.5 3.3 1.1 12.6 13.5 5.3 120.0 38.2 22.5 131.5 13.9 0.3 1.0 0.3 18.3 0.2 0.2 0.0 1.1 0.0 0.0 4.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.6 0.0 7.7 0.0 0.0 0.8 6.3 7.0 6.2 9.5 5.8 6.2 6.9 6.6 7.5 6.8 8.0 7.2 49.5 240.4 38.2 3.6 2.6 2.3 0.9 18.0 1.8 0.2 11.5 4.7 4.4 8.6 13.8 9.2 0.0 0.5 0.8 202.4 13.7 6.4 1.2 2.6 18.7 23.2 12.6 5.2 22.2 30.2 0.8 36.1 15.3 11.6 0.0 20.3 36.0 111.5 11.5 0.0 27.6 26.5 4.1 29.8 50.7 0.8 17.4 51.0 1.8 30.0 5.2 1.3 0.0 21.6 1.0 19.4 46.1 5.3 3.1 2.1 181.3 9.8 3.4 0.0 13.1 1.0 20.4 1.2 0.7 1.1 1.3 1.4 1.7 96.4 74.3 1.1 PARL "PRO2207, PSARL, PSARL1, RHBDS1" ENSG00000175193 "Presenilin associated rhomboid like" Q9H300 3 183829271-183884933 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA019545 Approved Approved Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA019545: AB_1855796" "unprognostic (2.10e-1)" "unprognostic (1.53e-3)" "unprognostic (5.88e-2)" "unprognostic (1.17e-2)" "unprognostic (5.76e-2)" "unprognostic (9.55e-2)" "unprognostic (3.17e-3)" "unprognostic (8.97e-2)" "unprognostic (1.81e-1)" "unprognostic (3.62e-3)" "unprognostic (1.52e-1)" "unprognostic (2.13e-2)" "unprognostic (4.28e-2)" "unprognostic (5.49e-2)" "unprognostic (2.58e-1)" "unprognostic (1.73e-1)" "prognostic favorable (9.11e-5)" 38.4 35.8 46.5 26.6 48.2 33.8 40.3 47.4 66.2 33.8 50.7 47.7 29.2 31.9 57.7 36.7 30.2 19.7 54.1 46.6 48.2 39.6 45.0 28.4 32.0 47.7 48.7 31.7 49.9 39.7 32.0 25.5 47.4 37.1 41.9 32.7 40.5 30.3 54.9 37.1 34.7 29.7 47.2 36.2 42.6 26.7 47.6 34.5 31.4 51.6 33.8 38.9 31.5 48.4 115.1 55.6 39.7 33.0 38.8 42.1 80.2 39.2 59.4 80.5 65.0 172.0 59.0 47.8 90.0 56.7 73.5 49.2 64.1 68.0 90.0 71.6 76.1 73.9 35.5 96.9 57.3 73.9 61.6 60.0 85.4 58.0 70.7 38.5 59.0 82.4 42.6 45.0 69.2 131.0 148.3 194.3 105.5 100.6 53.3 64.7 72.8 92.0 79.0 97.6 37.9 52.0 47.6 162.9 107.8 48.1 159.2 143.5 31.8 29.3 63.0 60.9 108.2 89.2 65.7 116.0 56.6 75.1 35.5 97.5 143.1 133.4 51.3 107.8 60.9 62.4 57.3 59.9 132.4 59.1 68.7 54.2 41.3 67.1 83.3 79.7 73.7 116.1 46.5 48.2 47.4 66.2 46.6 48.2 47.7 48.7 47.4 47.2 47.6 48.4 30.3 22.4 19.7 17.9 37.6 30.3 54.9 93.5 26.7 35.9 31.8 31.5 41.2 35.8 44.5 31.3 31.3 58.9 38.4 24.4 117.4 63.9 24.0 15.2 18.3 30.2 33.7 23.3 23.4 84.7 49.0 35.1 28.1 13.7 69.8 33.1 33.2 30.4 77.7 33.7 24.1 42.0 77.3 56.2 55.7 9.7 28.9 57.5 42.7 33.7 79.3 55.9 50.4 17.1 28.0 60.3 35.1 27.1 42.3 55.4 47.3 86.0 30.5 51.1 6.6 44.8 96.6 47.8 47.4 40.2 30.0 42.1 40.9 49.0 49.2 58.8 PARP15 "ARTD7, FLJ40597, pART7" ENSG00000173200 "Poly(ADP-ribose) polymerase family member 15" Q460N3 3 122577628-122639047 "Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 23.1;intestine: 42.1;lymphoid tissue: 67.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 19.2;B-cells: 88.4;dendritic cells: 38.6;granulocytes: 19.6;NK-cells: 21.6;Plasma cells: 18.6;T-cells: 31.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 7.6;JURKAT: 5.1;REH: 3.5;THP-1: 3.7;TIME: 8.9" "Low region specificity" "Detected in single" HPA035757 Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 57: B-cells - Immune response" Mitochondria "HPA035757: AB_10669656" "unprognostic (8.19e-3)" "unprognostic (2.88e-3)" "unprognostic (1.12e-1)" "unprognostic (1.18e-3)" "unprognostic (1.22e-1)" "unprognostic (9.01e-5)" "unprognostic (4.79e-2)" "unprognostic (1.83e-2)" "unprognostic (3.91e-2)" "unprognostic (5.40e-2)" "unprognostic (1.61e-1)" "unprognostic (9.63e-2)" "unprognostic (9.24e-7)" "unprognostic (9.03e-2)" "unprognostic (2.07e-2)" "unprognostic (1.52e-1)" "unprognostic (1.22e-2)" 3.7 1.2 3.1 25.7 2.7 23.1 1.8 4.2 3.8 1.7 1.2 3.8 2.6 1.9 1.3 2.0 2.0 4.4 1.7 2.1 1.2 1.7 3.2 9.0 44.4 1.8 2.3 0.7 0.8 0.2 0.7 2.5 1.7 1.8 4.8 2.2 2.2 1.1 6.0 1.2 42.1 1.9 0.7 67.2 4.1 2.5 2.0 8.3 3.0 1.9 50.3 4.5 1.6 3.6 0.3 0.2 0.3 0.3 0.1 0.2 0.3 0.2 0.1 0.0 0.0 0.2 0.7 0.3 0.4 0.1 0.2 0.3 0.0 0.0 0.0 0.7 0.1 7.6 0.5 0.3 0.1 0.5 0.3 1.5 0.1 0.3 0.1 0.2 1.7 5.1 0.2 1.3 0.0 0.3 2.3 0.4 0.4 0.1 0.1 3.5 0.2 0.3 0.0 0.6 0.5 0.3 0.1 0.1 0.1 0.3 0.5 3.7 8.9 0.2 0.6 0.3 0.2 0.6 0.4 1.6 0.4 0.2 0.1 1.8 0.2 0.1 7.2 0.3 5.8 9.4 4.4 5.4 0.8 9.3 3.8 4.8 0.5 3.9 0.7 1.0 4.2 2.2 3.1 2.7 4.2 3.8 2.1 1.2 1.8 2.3 1.7 0.7 2.0 3.6 0.8 19.2 15.9 0.0 88.4 0.5 0.0 0.0 0.0 0.0 0.6 0.6 0.7 0.0 2.1 0.0 0.0 0.1 38.6 0.1 0.0 0.0 0.2 0.3 0.1 1.2 0.0 7.4 0.1 0.0 0.1 2.7 2.6 0.3 19.6 0.0 2.2 0.6 8.3 0.0 0.2 0.0 0.0 5.1 1.4 0.2 0.0 6.4 1.8 6.5 4.7 0.0 21.6 0.0 0.1 0.1 0.0 0.0 18.6 0.0 0.0 0.1 10.5 0.0 0.0 0.7 0.4 0.1 1.6 0.4 0.0 0.3 31.1 0.0 0.0 0.0 PARP9 "ARTD9, BAL, BAL1" ENSG00000138496 "Poly(ADP-ribose) polymerase family member 9" Q8IXQ6 3 122527924-122564577 "Disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, DNA damage, DNA repair, Immunity, Innate immunity" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 95.8;BJ hTERT+ SV40 Large T+ RasG12V: 113.4;SK-MEL-30: 93.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA066708 Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" Mitochondria "HPA066708: AB_2685707" "unprognostic (3.06e-2)" "unprognostic (4.80e-2)" "unprognostic (1.55e-3)" "unprognostic (6.70e-3)" "unprognostic (1.11e-1)" "unprognostic (6.38e-2)" "unprognostic (4.73e-3)" "unprognostic (3.39e-3)" "unprognostic (1.31e-1)" "prognostic favorable (6.65e-4)" "unprognostic (1.00e-3)" "unprognostic (5.63e-3)" "unprognostic (1.56e-3)" "unprognostic (3.06e-2)" "unprognostic (3.70e-2)" "unprognostic (9.65e-3)" "unprognostic (1.56e-2)" 20.1 29.4 14.0 35.8 15.1 20.8 17.6 13.8 17.4 20.3 14.8 22.5 21.2 19.6 19.1 24.8 20.1 28.8 18.3 13.5 15.1 22.0 68.3 36.5 30.5 21.3 15.5 12.9 22.0 23.7 18.5 20.1 16.8 18.9 19.5 5.8 39.9 12.6 13.6 11.6 21.4 29.1 17.6 44.3 20.0 6.4 17.4 30.6 16.8 17.3 25.9 26.0 16.5 16.1 23.1 7.7 2.8 1.9 16.9 34.6 2.6 7.6 41.0 95.8 113.4 12.0 24.9 5.2 16.4 15.3 60.2 24.8 6.6 13.4 19.9 40.3 4.5 24.9 7.6 6.4 18.0 8.1 15.9 28.4 12.9 13.6 3.4 19.1 20.8 15.7 2.3 20.7 3.9 10.2 26.0 10.1 1.1 4.7 21.1 27.3 27.2 1.7 37.0 13.1 1.7 6.6 20.2 3.3 93.8 1.5 10.7 9.0 12.6 4.1 11.8 0.9 4.7 12.8 7.1 9.5 14.1 8.7 7.7 41.9 29.9 36.9 19.8 41.1 18.5 15.9 20.6 22.3 27.5 11.4 15.6 19.3 87.5 30.2 45.2 3.3 24.9 23.3 14.0 15.1 13.8 17.4 13.5 15.1 21.3 15.5 16.8 17.6 17.4 16.1 37.0 41.7 44.2 13.4 18.9 7.1 10.8 13.8 12.5 0.8 10.5 6.3 5.8 10.0 35.1 20.2 0.0 5.2 14.0 32.5 1.9 30.4 1.6 23.6 28.1 37.4 10.7 19.0 0.3 39.9 19.3 19.9 22.4 23.2 10.1 19.5 21.8 50.1 42.0 0.0 1.3 11.5 10.2 32.3 9.2 4.5 18.3 41.2 7.2 45.0 50.2 12.1 32.0 17.1 3.9 36.8 11.7 24.0 13.6 8.9 17.5 19.3 48.8 1.0 19.7 18.9 16.3 0.9 1.9 15.7 6.7 1.6 23.5 17.0 8.6 14.4 PARS2 DKFZp727A071 ENSG00000162396 "Prolyl-tRNA synthetase 2, mitochondrial" Q7L3T8 1 54756898-54764523 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 9.8;Early spermatids: 11.0;Spermatocytes: 10.5;Spermatogonia: 11.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028308, HPA028314, HPA028518" Uncertain Approved "Nucleoli fibrillar center,Mitochondria" No No "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nucleoli fibrillar center, Mitochondria" "HPA028308: AB_2672553, HPA028314: AB_10603981, HPA028518: AB_2672653" "unprognostic (1.95e-1)" "unprognostic (1.10e-1)" "prognostic favorable (1.26e-5)" "unprognostic (1.93e-2)" "unprognostic (1.19e-2)" "unprognostic (1.79e-3)" "prognostic unfavorable (2.34e-4)" "unprognostic (6.48e-2)" "unprognostic (2.72e-1)" "unprognostic (1.14e-1)" "unprognostic (9.42e-2)" "unprognostic (1.10e-1)" "prognostic favorable (1.24e-6)" "unprognostic (2.72e-2)" "unprognostic (9.77e-2)" "unprognostic (1.73e-2)" "unprognostic (9.64e-2)" 1.3 2.9 2.5 1.9 3.0 0.2 2.7 2.8 3.1 2.7 3.0 4.0 2.7 2.5 3.2 2.7 4.4 1.6 3.0 2.6 2.6 4.2 3.4 1.4 2.0 2.5 2.7 4.8 2.3 4.7 2.1 2.5 2.7 2.3 3.6 2.0 3.3 2.8 4.4 2.9 2.1 2.0 2.7 1.8 2.5 4.8 2.7 2.6 2.9 5.5 2.4 2.1 2.0 3.0 4.4 7.2 4.6 6.0 5.5 4.6 10.3 3.7 4.5 6.4 4.6 8.3 2.8 7.7 5.6 3.3 9.3 6.9 8.3 5.8 4.7 5.0 7.5 7.4 4.0 6.2 8.5 4.3 2.5 5.0 8.8 8.3 7.4 5.5 4.8 8.4 13.2 1.0 4.9 4.6 6.1 5.7 10.6 8.3 9.1 4.6 9.0 9.0 5.4 3.2 4.7 4.8 5.3 6.9 9.7 8.7 3.9 5.5 2.6 4.8 4.9 6.8 4.7 7.3 6.6 3.0 3.6 5.1 2.8 1.2 5.3 4.5 4.8 7.7 5.9 4.9 5.3 5.3 7.3 5.5 7.8 5.3 0.5 7.4 10.7 5.9 8.2 5.0 2.5 3.0 2.8 3.1 2.6 2.6 2.5 2.7 2.7 2.7 2.7 3.0 0.6 0.0 1.1 0.3 1.0 0.6 0.9 2.0 1.8 2.6 1.3 1.9 1.5 2.8 1.8 0.0 0.0 7.0 0.2 2.4 9.8 4.5 11.0 1.1 1.4 0.8 0.0 0.0 0.9 2.8 3.9 1.3 1.5 0.6 0.0 2.9 0.0 2.3 3.1 5.0 1.1 2.8 0.0 1.2 0.3 6.8 3.7 0.8 0.0 2.8 1.1 3.2 0.0 0.5 1.6 1.9 1.5 3.0 0.3 1.8 1.5 6.5 1.0 1.9 0.0 1.3 1.1 10.5 11.5 2.0 1.0 3.3 0.7 5.1 3.5 0.8 PCBP3 "FLJ44028, PCBP3-OT1, PCBP3OT" ENSG00000183570 "Poly(rC) binding protein 3" P57721 21 45643694-45942454 "Plasma proteins, Predicted intracellular proteins" "DNA-binding, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 34.6;retina: 81.5" "Cell type enhanced" "Detected in many" "Bipolar cells: 159.4;Cone photoreceptor cells: 50.1;Horizontal cells: 116.1;Late spermatids: 79.8;Muller glia cells: 49.3;Rod photoreceptor cells: 83.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 29.0;HDLM-2: 56.9;HSkMC: 40.8;SH-SY5Y: 46.9;U-87 MG: 25.0;U-937: 31.3" "Region enriched" "Detected in all" 5 "olfactory bulb: 229.1" "HPA030247, HPA073145" Approved Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 46: Basophils - DNA binding" "Cluster 77: Retina - Visual perception" "Cluster 44: HDLM-2 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Mitochondria" Vesicles "HPA030247: AB_10601244, HPA073145: " "unprognostic (3.88e-2)" "unprognostic (1.19e-1)" "unprognostic (2.01e-4)" "unprognostic (9.89e-4)" "unprognostic (2.74e-1)" "unprognostic (1.40e-1)" "unprognostic (4.10e-2)" "unprognostic (2.42e-1)" "unprognostic (3.87e-2)" "unprognostic (1.64e-3)" "unprognostic (1.12e-3)" "unprognostic (1.97e-2)" "unprognostic (1.96e-6)" "unprognostic (8.67e-2)" "unprognostic (2.32e-2)" "unprognostic (8.04e-2)" "unprognostic (1.97e-2)" 7.3 7.1 8.9 7.5 6.8 8.9 4.5 34.6 11.9 8.2 2.8 13.7 1.7 8.7 7.5 1.4 5.3 2.6 3.4 13.5 8.1 4.8 1.3 2.8 3.3 32.3 12.0 3.9 2.7 0.1 22.6 1.2 31.3 2.3 1.6 81.5 1.8 0.8 0.4 2.1 8.7 7.8 8.9 10.0 4.7 14.8 17.9 18.9 1.0 1.7 2.9 4.1 2.8 9.5 0.0 0.0 0.5 0.0 13.7 29.0 0.2 1.8 0.4 3.1 1.4 0.0 0.0 0.0 0.7 8.2 3.9 0.1 1.7 0.0 0.5 56.9 0.2 0.0 0.0 0.0 13.7 0.0 0.0 40.8 0.2 0.5 0.8 0.0 0.0 2.0 0.0 0.2 1.8 0.7 16.5 3.3 0.8 0.1 2.8 0.0 0.1 2.4 0.0 0.0 4.9 46.9 1.2 0.0 0.0 1.3 0.0 8.7 0.0 0.0 0.1 12.3 0.0 0.7 3.1 0.0 25.0 31.3 1.1 2.1 0.2 3.0 0.7 0.1 0.1 1.3 0.4 0.0 0.0 1.4 0.7 0.1 0.7 0.3 0.1 0.0 0.4 0.2 8.9 6.8 34.6 11.9 13.5 8.1 32.3 12.0 31.3 8.9 17.9 9.5 0.6 0.0 0.0 2.3 6.2 0.3 0.1 0.3 0.0 159.4 0.1 0.5 3.6 0.0 0.7 1.8 50.1 0.1 0.3 0.0 0.0 0.1 36.5 0.2 8.9 2.2 3.0 0.0 3.8 0.2 0.1 2.3 0.5 0.3 0.0 0.2 2.2 0.0 0.4 116.1 4.6 0.1 0.0 0.0 0.7 79.8 8.4 0.9 3.6 1.0 0.0 49.3 0.0 0.5 5.5 0.9 0.1 12.8 4.1 1.3 0.0 0.4 0.0 83.1 0.0 1.1 3.9 34.1 21.2 0.0 0.0 0.0 2.5 0.2 0.2 0.5 PCDHA5 "CNR6, CNRN6, CNRS6, CRNR6, PCDH-ALPHA5" ENSG00000204965 "Protocadherin alpha 5" Q9Y5H7 5 140821604-141012347 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "brain: 3.3" "Cell type enriched" "Detected in some" 4 "Horizontal cells: 6.7" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 3.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 1.3;EFO-21: 3.4;T-47d: 3.7;WM-115: 1.3" "Low region specificity" "Detected in many" HPA044557 Approved Approved "Nuclear speckles,Plasma membrane,Mitochondria" NA NA "Cluster 6: Brain - Smell perception" "Cluster 6: T47d - Mammary gland" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "Nuclear speckles, Mitochondria" "HPA044557: AB_10970597" "unprognostic (4.95e-2)" "unprognostic (6.23e-2)" "unprognostic (2.06e-1)" "unprognostic (8.81e-4)" "unprognostic (5.10e-2)" "unprognostic (6.25e-3)" "unprognostic (6.74e-2)" "unprognostic (9.79e-2)" "unprognostic (2.46e-2)" "unprognostic (4.49e-2)" "unprognostic (1.44e-2)" "unprognostic (1.10e-4)" "unprognostic (9.30e-4)" "unprognostic (1.07e-1)" "unprognostic (1.39e-1)" "unprognostic (8.17e-5)" "unprognostic (2.11e-1)" 0.1 0.1 0.6 0.0 1.0 0.0 0.1 3.3 1.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.2 0.0 0.5 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.3 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 3.7 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 1.0 3.3 1.1 0.9 0.0 0.1 0.1 0.2 0.0 0.1 0.6 0.3 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PCDHAC2 PCDH-ALPHA-C2 ENSG00000243232 "Protocadherin alpha subfamily C, 2" Q9Y5I4 5 140966470-141012347 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.9;parathyroid gland: 42.9" "Group enriched" "Detected in some" 4 "Bipolar cells: 1.3;Hepatic stellate cells: 2.2;Respiratory ciliated cells: 1.6;Rod photoreceptor cells: 1.4" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "AN3-CA: 58.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076190 Approved Nucleoplasm,Mitochondria NA NA 1100000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm Mitochondria "HPA076190: AB_2686785" "unprognostic (1.47e-1)" "unprognostic (3.58e-3)" "unprognostic (2.59e-1)" "unprognostic (5.31e-4)" "unprognostic (3.89e-1)" "unprognostic (1.82e-2)" "unprognostic (5.03e-2)" "unprognostic (1.79e-1)" "unprognostic (1.26e-1)" "unprognostic (2.13e-2)" "unprognostic (2.45e-1)" "unprognostic (1.41e-1)" "unprognostic (2.30e-1)" "unprognostic (4.46e-4)" "unprognostic (9.90e-2)" "unprognostic (1.34e-1)" "unprognostic (1.08e-3)" 0.6 1.1 4.0 0.5 4.6 0.0 0.1 3.5 6.6 0.9 0.0 0.3 0.1 0.6 0.1 0.0 0.2 2.6 0.7 4.9 1.7 0.4 0.7 2.2 2.1 0.8 16.9 0.1 0.4 42.9 1.6 1.8 6.0 0.3 0.3 9.7 0.6 0.1 0.0 0.1 0.2 1.0 0.0 1.7 0.5 1.6 2.8 0.0 1.2 0.0 0.6 0.2 0.0 2.3 0.0 13.1 1.2 58.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 3.7 0.0 2.5 0.1 1.3 6.9 0.0 0.0 0.2 0.0 13.7 0.0 0.8 0.0 0.0 0.2 8.8 0.0 2.4 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 2.5 0.0 2.3 0.0 0.0 0.0 1.7 0.1 2.7 10.6 0.0 0.0 0.1 1.2 2.6 0.4 0.0 1.1 1.2 0.0 0.6 0.0 0.0 0.0 0.7 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 4.6 3.5 6.6 4.9 1.7 0.8 16.9 6.0 0.0 2.8 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 2.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.6 1.4 0.0 0.0 0.2 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 PCDHB15 PCDH-BETA15 ENSG00000113248 "Protocadherin beta 15" Q9Y5E8 5 141245395-141249365 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 4.3;Bipolar cells: 4.4;Early spermatids: 7.5;Endometrial stromal cells: 4.4;Fibroblasts: 3.7;Horizontal cells: 5.0;Skeletal myocytes: 4.2;Smooth muscle cells: 4.1;Spermatocytes: 4.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 6.2;LHCN-M2: 4.9;WM-115: 4.9" "Low region specificity" "Detected in all" "HPA007172, CAB026471, HPA074676" Uncertain Approved Mitochondria NA NA 250000 "Cluster 21: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "CAB026471: , HPA007172: AB_1079576, HPA074676: AB_2732263" "unprognostic (1.39e-1)" "unprognostic (1.58e-1)" "unprognostic (7.37e-3)" "unprognostic (1.75e-1)" "unprognostic (2.06e-2)" "unprognostic (6.19e-2)" "unprognostic (1.60e-1)" "unprognostic (4.12e-2)" "unprognostic (1.87e-2)" "unprognostic (7.58e-2)" "unprognostic (7.01e-2)" "unprognostic (6.00e-2)" "unprognostic (9.37e-2)" "unprognostic (1.08e-2)" "unprognostic (2.02e-1)" "unprognostic (1.08e-1)" "unprognostic (1.59e-1)" 3.8 1.4 1.9 2.5 2.1 0.0 2.6 4.2 2.4 6.4 0.0 3.8 0.5 6.8 2.5 1.4 5.0 2.1 4.4 1.8 1.6 2.1 1.1 3.7 0.7 3.0 2.5 7.4 3.3 0.8 3.5 1.5 2.0 2.4 0.9 2.0 1.7 2.0 1.3 1.3 1.8 4.1 2.5 2.5 2.1 5.4 2.3 0.3 2.7 1.4 0.5 3.6 3.2 2.4 0.2 0.0 6.2 0.7 1.5 1.6 0.1 0.4 1.2 0.1 0.3 0.0 0.3 0.0 1.2 0.9 1.6 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.9 0.2 0.2 0.0 0.0 0.7 1.3 0.0 0.2 1.6 0.3 0.0 0.0 1.0 4.9 0.0 0.0 0.1 1.5 0.0 0.0 0.2 0.7 0.0 0.4 0.1 0.3 0.8 0.3 0.3 1.6 0.8 0.3 0.0 0.0 0.6 0.6 2.2 0.0 0.1 0.8 0.0 0.8 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.1 4.2 2.4 1.8 1.6 3.0 2.5 2.0 2.5 2.3 2.4 4.3 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 4.4 0.2 0.3 1.4 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.2 7.5 0.2 4.4 2.4 0.0 0.0 0.0 1.5 0.0 3.7 0.5 0.2 0.0 0.6 1.4 0.0 0.1 5.0 0.0 0.0 0.0 0.0 0.0 2.3 0.6 0.0 1.8 0.0 0.0 1.3 0.0 0.0 0.0 0.9 0.1 3.4 0.0 0.1 0.0 0.7 0.1 0.8 0.0 4.2 4.1 4.8 0.7 0.2 0.6 0.0 0.1 0.5 0.1 0.3 PCF11 KIAA0824 ENSG00000165494 "PCF11 cleavage and polyadenylation factor subunit" O94913 11 83156988-83187451 "Plasma proteins, Predicted intracellular proteins" "mRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Skeletal myocytes: 227.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 124.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040779 Supported Nucleoplasm,Mitochondria NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Mitochondria "HPA040779: AB_2677133" "unprognostic (1.53e-1)" "unprognostic (7.24e-2)" "unprognostic (3.99e-2)" "unprognostic (1.18e-1)" "unprognostic (3.24e-3)" "prognostic favorable (1.34e-4)" "unprognostic (3.74e-2)" "unprognostic (4.89e-3)" "unprognostic (1.12e-3)" "unprognostic (9.53e-2)" "unprognostic (6.07e-2)" "unprognostic (5.63e-2)" "unprognostic (1.55e-1)" "unprognostic (3.91e-3)" "unprognostic (1.15e-1)" "unprognostic (1.07e-1)" "prognostic favorable (2.03e-5)" 20.1 13.9 9.8 23.5 15.0 42.5 23.7 29.1 13.6 19.2 6.0 19.6 16.3 22.4 15.2 19.5 17.7 17.2 13.5 9.3 10.9 14.9 16.9 22.8 32.4 13.1 12.7 28.3 17.0 16.6 10.4 16.7 14.0 18.7 19.9 26.6 15.4 16.2 26.3 27.8 20.8 23.8 10.9 28.7 16.4 24.7 12.1 33.4 24.3 19.5 29.6 17.0 13.5 17.9 26.3 18.4 29.4 25.3 34.4 33.4 23.5 24.7 18.2 23.2 17.7 31.5 25.7 58.9 18.1 18.0 21.9 25.8 43.2 17.0 22.3 42.1 14.8 34.5 26.3 22.4 19.4 40.9 36.8 23.9 32.1 17.7 25.6 31.2 23.8 38.8 40.9 27.9 21.9 27.9 38.7 45.2 30.7 44.6 20.5 36.4 37.1 35.2 20.2 38.4 24.4 27.0 30.1 23.7 24.3 26.9 23.7 28.0 24.6 33.0 16.9 24.5 16.6 25.0 45.2 124.6 14.5 26.8 26.0 14.8 7.2 14.9 10.1 6.8 8.5 10.9 6.9 7.3 6.9 9.9 7.8 8.2 17.1 13.5 5.5 7.1 5.5 5.8 9.8 15.0 29.1 13.6 9.3 10.9 13.1 12.7 14.0 10.9 12.1 17.9 96.4 41.7 63.5 58.1 90.6 53.7 79.8 30.7 101.9 48.4 84.4 81.0 42.7 35.8 43.4 46.0 33.3 30.2 90.1 49.8 25.4 22.9 203.3 55.5 70.8 66.8 31.8 62.5 32.0 18.1 26.9 58.8 40.2 83.6 37.2 48.0 56.7 21.7 37.6 55.5 37.9 51.0 26.4 57.8 41.0 40.3 60.3 87.4 28.4 45.0 52.5 34.5 58.7 40.7 72.0 19.2 46.2 45.1 69.0 71.6 83.4 14.2 29.0 55.3 39.5 227.3 66.8 46.7 17.9 100.4 62.7 39.4 81.7 42.7 50.3 71.1 PCMTD2 "C20orf36, FLJ10883" ENSG00000203880 "Protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2" Q9NV79 20 64255695-64287821 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 180.5" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 138.2;Rod photoreceptor cells: 181.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057849 Approved Approved Nucleoplasm,Mitochondria No No "Cluster 20: T-cells - T-cell receptor" "Cluster 77: Retina - Visual perception" "Cluster 24: NB-4 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" Mitochondria Nucleoplasm "HPA057849: AB_2683544" "unprognostic (2.41e-1)" "unprognostic (2.31e-2)" "unprognostic (2.62e-1)" "unprognostic (2.88e-2)" "unprognostic (2.23e-1)" "unprognostic (3.17e-2)" "unprognostic (1.59e-1)" "prognostic favorable (2.13e-4)" "unprognostic (1.07e-1)" "unprognostic (4.07e-2)" "unprognostic (1.90e-2)" "unprognostic (1.40e-2)" "prognostic favorable (3.82e-4)" "unprognostic (1.10e-1)" "unprognostic (3.46e-2)" "unprognostic (4.43e-2)" "unprognostic (7.05e-3)" 31.4 33.6 27.2 22.9 31.0 17.8 37.5 40.2 40.7 36.7 28.3 25.3 23.3 39.2 49.2 22.8 29.0 32.5 42.5 27.1 30.5 34.2 32.1 24.0 41.6 27.1 25.9 57.0 27.0 27.7 31.8 41.2 25.3 29.5 20.3 180.5 32.3 18.3 44.6 66.0 25.0 19.0 24.9 36.3 21.7 24.7 28.4 39.5 27.1 32.9 29.6 20.6 28.1 38.9 22.9 8.5 32.0 25.0 30.1 37.1 30.1 13.6 15.1 19.7 12.0 19.4 35.9 33.8 23.5 16.6 15.6 27.6 17.6 22.4 26.5 7.4 23.0 16.4 42.1 32.9 25.3 16.9 24.0 52.7 30.5 10.4 17.9 35.1 29.1 34.0 30.4 29.8 16.3 14.8 39.8 56.7 23.5 31.6 31.7 32.6 12.6 41.1 30.0 26.1 50.0 58.9 26.1 30.1 37.2 49.4 32.2 34.1 21.2 29.4 10.3 18.9 11.3 35.8 31.3 32.9 19.5 17.9 16.1 10.1 7.9 9.4 9.4 5.4 11.2 10.2 14.0 10.7 9.0 10.7 19.2 14.2 10.2 17.4 5.3 5.4 22.6 9.8 27.2 31.0 40.2 40.7 27.1 30.5 27.1 25.9 25.3 24.9 28.4 38.9 40.8 22.4 26.9 25.8 21.0 20.4 15.6 10.2 31.3 118.5 27.5 18.0 67.4 28.6 17.5 29.5 93.8 33.7 21.9 6.7 23.5 8.4 13.2 21.3 23.2 36.6 22.8 35.3 34.8 9.1 7.0 34.8 17.9 26.4 12.7 33.5 45.0 36.7 14.4 37.0 29.5 15.9 14.2 28.8 10.7 9.5 42.9 17.3 48.0 21.5 19.2 61.3 20.6 138.2 64.6 9.9 15.7 30.9 20.2 14.6 12.0 23.3 24.3 181.9 26.3 25.0 27.7 51.7 37.7 24.9 21.3 21.9 21.6 63.1 15.2 11.3 PCP4L1 IQM1 ENSG00000248485 "Purkinje cell protein 4 like 1" A6NKN8 1 161258745-161285450 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 71.7;pituitary gland: 84.3" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 35.8;Bipolar cells: 82.8;Inhibitory neurons: 34.0;Sertoli cells: 19.7;Squamous epithelial cells: 23.5;Urothelial cells: 39.9" "Cancer enhanced" "Detected in many" "urothelial cancer: 21.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "RT4: 13.8;T-47d: 8.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "olfactory bulb: 206.6" HPA052833 Enhanced Supported Approved Nucleoplasm,Mitochondria NA NA "Cluster 35: T-regs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 15: RT4 - Unknown function" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Mitochondria" "HPA052833: AB_2681968" "unprognostic (1.81e-2)" "unprognostic (9.39e-2)" "unprognostic (5.25e-2)" "unprognostic (2.07e-1)" "unprognostic (3.03e-2)" "unprognostic (1.87e-2)" "unprognostic (2.51e-1)" "prognostic favorable (8.10e-5)" "unprognostic (2.39e-1)" "unprognostic (1.92e-1)" "unprognostic (4.93e-2)" "unprognostic (7.37e-2)" "unprognostic (3.63e-5)" "unprognostic (4.81e-2)" "unprognostic (1.25e-1)" "unprognostic (2.09e-1)" "unprognostic (6.15e-2)" 2.7 0.4 14.1 0.8 71.7 0.1 1.8 19.6 33.2 4.0 0.9 5.6 1.7 1.8 2.6 18.8 2.1 2.0 0.8 6.8 14.7 0.9 4.0 4.6 0.2 39.7 23.3 2.2 0.5 0.4 84.3 0.3 39.8 11.0 2.5 39.2 1.9 16.4 0.4 5.6 2.8 6.6 28.1 0.3 2.0 1.8 15.2 2.0 0.7 1.5 2.6 35.6 17.1 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 1.7 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.3 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.1 0.0 13.8 1.9 0.0 0.0 0.2 0.0 0.2 8.9 0.3 0.2 0.0 0.0 0.0 0.0 0.8 0.9 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 14.1 71.7 19.6 33.2 6.8 14.7 39.7 23.3 39.8 28.1 15.2 13.9 0.0 3.2 6.4 2.0 0.0 0.0 35.8 8.3 12.5 82.8 3.2 1.0 0.2 0.0 7.6 0.0 6.2 0.4 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.3 0.0 0.0 3.1 1.3 1.9 0.2 4.6 0.3 1.3 0.0 0.0 0.9 0.1 0.0 34.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.8 0.0 3.5 0.0 5.0 1.4 0.2 0.0 1.9 0.0 2.5 0.0 0.6 0.9 5.9 19.7 0.0 10.0 1.3 1.5 23.5 0.3 1.8 0.0 0.0 0.0 39.9 PCYOX1L MGC3265 ENSG00000145882 "Prenylcysteine oxidase 1 like" Q8NBM8 5 149358037-149369653 "Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 17.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 50.2;RPMI-8226: 50.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037463, HPA038402" Approved Approved Nucleoplasm,Mitochondria "Secreted to blood" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 25: RPMI-8226 - Immune response" "Cluster 58: T-cells - T-cell receptor" "Nucleoplasm, Mitochondria" "HPA037463: AB_10673632, HPA038402: AB_2675997" "unprognostic (1.34e-1)" "unprognostic (9.88e-3)" "unprognostic (2.04e-1)" "unprognostic (1.22e-1)" "unprognostic (7.83e-2)" "unprognostic (5.73e-2)" "unprognostic (4.18e-3)" "unprognostic (7.51e-3)" "unprognostic (2.30e-1)" "unprognostic (1.25e-1)" "unprognostic (3.05e-3)" "unprognostic (8.77e-2)" "unprognostic (4.90e-2)" "unprognostic (2.86e-1)" "unprognostic (2.49e-1)" "unprognostic (2.26e-3)" "unprognostic (3.28e-1)" 3.2 4.6 2.3 5.3 2.4 3.9 3.3 2.4 4.5 5.1 0.2 3.2 1.8 4.9 0.6 3.5 5.3 4.7 3.9 2.9 4.4 2.0 0.5 3.4 6.6 3.7 2.5 5.7 3.1 17.5 4.9 4.2 5.0 3.9 0.7 7.6 2.9 4.5 0.8 5.4 4.8 5.2 1.0 4.0 3.7 6.4 2.3 4.6 2.7 1.8 3.2 3.8 3.8 2.3 4.3 2.7 9.2 20.3 7.8 7.9 4.9 9.0 4.0 7.8 13.2 0.8 7.6 17.9 27.1 6.7 36.1 7.7 8.8 20.3 0.7 8.4 8.2 8.4 0.0 0.7 17.3 7.3 9.1 14.9 3.0 10.7 12.6 9.4 17.3 16.6 4.9 50.2 0.4 17.9 8.1 11.2 4.7 15.8 16.3 10.7 6.7 50.8 4.9 2.0 13.3 13.6 17.9 11.9 14.6 10.0 20.0 12.4 8.2 6.8 5.5 14.7 4.2 20.1 29.2 10.6 11.2 38.3 14.6 3.0 7.1 4.0 2.8 9.6 3.7 1.6 5.3 2.1 13.2 1.0 6.3 4.4 1.2 4.8 9.6 0.9 7.3 4.7 2.3 2.4 2.4 4.5 2.9 4.4 3.7 2.5 5.0 1.0 2.3 2.3 4.5 9.6 1.7 2.9 2.3 1.0 1.0 3.2 2.8 5.2 2.4 1.8 5.3 4.3 3.6 1.8 0.0 6.0 1.9 0.6 0.0 3.0 3.3 3.2 2.4 4.6 0.0 2.5 10.5 2.3 6.6 5.0 2.0 2.3 2.5 9.6 2.5 0.4 7.6 11.8 12.4 1.8 6.1 8.2 1.4 1.5 3.4 6.9 1.8 4.7 7.0 7.8 1.0 5.5 4.9 2.1 1.7 2.6 1.3 0.8 2.6 0.6 2.8 14.2 0.0 2.5 2.7 1.2 3.5 1.9 1.6 1.2 5.6 9.7 2.3 0.9 PDCD2L MGC13096 ENSG00000126249 "Programmed cell death 2 like" Q9BRP1 19 34404399-34426168 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 24.7" "Cell type enhanced" "Detected in many" "Spermatocytes: 35.7;Spermatogonia: 42.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052181 Approved Approved Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 80: Striated muscle - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA052181: AB_2681751" "unprognostic (5.39e-2)" "unprognostic (3.48e-1)" "unprognostic (1.51e-1)" "unprognostic (6.99e-2)" "unprognostic (1.07e-1)" "unprognostic (3.22e-1)" "prognostic unfavorable (5.81e-4)" "unprognostic (1.82e-1)" "unprognostic (1.49e-1)" "unprognostic (8.78e-2)" "unprognostic (1.30e-2)" "unprognostic (2.39e-1)" "prognostic unfavorable (1.23e-5)" "unprognostic (1.75e-1)" "unprognostic (1.72e-1)" "unprognostic (3.00e-2)" "unprognostic (5.98e-2)" 4.2 5.6 5.0 2.7 5.3 3.1 4.1 4.8 5.8 4.3 4.2 5.3 2.6 5.0 2.9 5.3 5.0 2.1 7.5 5.0 5.6 3.5 5.5 2.9 4.7 4.5 4.7 4.4 8.3 2.2 5.8 2.5 4.9 3.4 3.4 1.1 5.5 3.8 24.7 4.7 4.0 3.1 4.7 4.8 6.5 14.4 5.4 2.9 3.1 9.1 4.8 4.8 3.9 5.7 21.6 35.9 4.4 8.7 2.0 4.2 13.8 6.8 4.9 11.1 11.1 33.6 15.1 17.7 28.8 3.9 11.6 7.4 17.4 14.9 11.7 26.1 36.6 17.4 5.7 26.8 14.5 34.0 9.8 5.1 12.9 6.5 21.2 4.6 11.3 28.0 35.1 9.0 9.6 27.3 13.4 12.4 16.0 47.3 34.4 19.2 8.2 25.1 14.1 12.1 25.8 9.2 0.7 21.4 12.5 7.3 9.3 13.9 6.0 7.3 9.0 8.6 23.4 20.1 32.8 31.4 9.1 29.8 6.3 0.0 3.3 0.0 9.1 5.3 12.9 12.7 8.9 9.0 6.8 10.1 13.1 9.9 0.7 12.5 3.4 23.6 11.7 5.7 5.0 5.3 4.8 5.8 5.0 5.6 4.5 4.7 4.9 4.7 5.4 5.7 5.5 3.2 4.8 3.6 7.6 8.2 15.0 7.6 10.2 4.3 4.8 7.4 5.1 5.7 4.8 3.7 2.1 8.1 12.0 1.7 7.9 13.3 27.4 6.3 4.3 4.9 12.1 4.6 4.2 15.3 7.0 5.1 9.2 2.7 4.5 5.6 5.0 5.1 7.5 1.7 4.3 5.0 2.0 3.3 3.7 3.9 5.3 4.1 3.6 2.8 7.1 4.8 9.2 4.0 3.4 13.1 5.0 6.8 8.2 27.6 1.1 10.2 6.1 2.4 0.0 6.1 12.6 35.7 42.9 7.5 10.7 1.8 5.4 8.2 7.7 9.6 PDF ENSG00000258429 "Peptide deformylase, mitochondrial" Q9HBH1 16 69326913-69330588 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Protein biosynthesis" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 27.8" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 8.0;Erythroid cells: 4.6;Gastric mucus-secreting cells: 8.6;Plasma cells: 14.7;Squamous epithelial cells: 17.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA063409 Approved Approved Nucleoplasm,Mitochondria "Intracellular and membrane" No No "Cluster 24: B-cells - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 59: Non-specific - Transcription" Mitochondria Nucleoplasm "HPA063409: AB_2685007" "unprognostic (4.28e-2)" "prognostic unfavorable (4.63e-4)" "unprognostic (1.37e-1)" "unprognostic (1.47e-1)" "unprognostic (2.85e-1)" "prognostic unfavorable (2.73e-4)" "unprognostic (2.98e-3)" "prognostic unfavorable (7.35e-4)" "unprognostic (5.84e-2)" "unprognostic (4.35e-1)" "unprognostic (1.02e-1)" "unprognostic (1.00e-1)" "prognostic favorable (6.11e-4)" "unprognostic (4.78e-2)" "unprognostic (1.05e-1)" "unprognostic (5.98e-2)" "unprognostic (1.22e-2)" 5.9 8.7 1.0 0.9 1.3 1.4 5.5 1.9 1.8 4.4 1.5 5.6 2.1 5.8 0.4 10.2 4.7 0.5 5.3 2.2 0.8 19.0 27.8 4.4 1.1 1.4 0.8 3.1 8.8 1.6 4.3 0.6 1.0 5.0 0.8 0.3 7.2 0.6 12.4 7.7 5.2 0.4 0.8 5.1 5.6 4.8 0.9 0.6 5.9 0.8 0.7 4.8 4.8 1.5 6.3 4.8 1.3 4.1 1.1 0.8 7.7 6.0 1.0 2.9 2.4 8.6 5.7 13.1 6.2 1.6 2.2 11.5 1.8 2.1 1.3 3.5 23.3 6.6 5.3 12.6 1.8 10.8 5.7 1.7 4.3 2.5 1.2 0.8 1.5 7.2 16.1 2.4 1.9 7.6 9.2 8.3 6.4 2.6 7.1 20.8 2.1 11.0 2.2 5.4 9.3 7.1 10.8 2.9 5.2 0.3 11.0 3.3 4.6 3.9 6.4 5.8 6.8 12.1 9.4 15.2 3.1 6.9 5.9 1.4 0.7 1.0 0.4 0.3 0.9 1.2 1.0 1.2 0.6 4.1 1.5 0.7 0.0 0.4 0.4 1.3 0.9 0.3 1.0 1.3 1.9 1.8 2.2 0.8 1.4 0.8 1.0 0.8 0.9 1.5 0.2 3.2 0.0 0.0 3.0 0.0 0.1 0.0 8.0 0.0 0.3 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.5 0.3 0.6 0.0 4.6 0.0 0.2 0.3 1.2 8.6 0.5 0.0 0.2 0.4 0.8 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 14.7 0.1 0.4 1.1 0.0 0.0 0.0 0.1 0.8 0.2 0.1 17.7 0.4 0.3 1.4 0.1 0.0 0.1 PDHX "DLDBP, E3BP, OPDX, PDX1, proX" ENSG00000110435 "Pyruvate dehydrogenase complex component X" O00330 11 34915829-35020591 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 138.6;tongue: 125.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 115.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038484, HPA038485" Enhanced Approved "Nucleoplasm,Plasma membrane,Mitochondria" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Plasma membrane" Mitochondria "HPA038484: AB_10669645, HPA038485: AB_10669540" "unprognostic (1.60e-1)" "unprognostic (1.91e-1)" "unprognostic (1.42e-2)" "unprognostic (1.06e-1)" "unprognostic (2.03e-1)" "unprognostic (8.34e-3)" "unprognostic (3.56e-3)" "unprognostic (1.94e-1)" "unprognostic (2.14e-1)" "unprognostic (5.41e-2)" "unprognostic (2.60e-2)" "unprognostic (2.08e-1)" "prognostic favorable (1.83e-5)" "unprognostic (2.24e-1)" "unprognostic (8.28e-2)" "unprognostic (9.53e-2)" "unprognostic (2.82e-1)" 23.5 21.6 16.5 12.2 19.9 7.4 16.6 21.6 21.9 13.3 9.4 22.8 20.1 14.2 13.3 17.2 10.0 12.3 77.8 21.1 14.5 21.5 31.0 12.7 11.9 16.6 17.2 11.7 21.5 21.0 15.4 24.4 16.5 18.9 20.6 27.1 20.4 16.0 138.6 14.6 15.0 17.8 13.4 11.1 23.1 27.8 19.7 13.2 14.3 125.2 14.8 15.0 11.7 21.1 20.4 54.3 29.9 11.9 20.7 25.5 28.5 38.9 30.1 40.3 38.9 69.3 18.8 27.2 24.7 31.4 49.1 39.4 58.9 31.9 41.1 25.8 47.2 26.9 54.6 82.3 45.0 50.7 30.7 25.6 37.9 23.2 31.5 23.8 31.1 23.9 57.9 25.4 33.1 35.7 32.2 29.9 25.2 54.2 30.5 27.0 53.5 23.8 62.1 54.7 32.0 23.3 33.8 48.1 52.2 29.3 54.8 29.9 21.0 30.4 35.5 32.3 42.7 24.4 53.3 35.7 23.9 24.2 32.5 14.0 19.4 17.5 15.4 21.4 14.3 18.8 14.4 12.7 27.5 16.0 17.2 12.6 3.9 22.1 34.6 7.4 22.1 14.7 16.5 19.9 21.6 21.9 21.1 14.5 16.6 17.2 16.5 13.4 19.7 21.1 9.0 35.3 24.6 34.3 14.5 26.0 21.4 26.7 15.4 25.8 15.1 11.4 115.3 20.0 26.0 5.5 29.2 62.9 9.0 14.4 64.6 21.4 52.6 15.1 12.2 13.0 9.0 13.5 85.4 14.3 34.9 20.6 16.3 16.6 5.7 16.5 11.7 23.6 26.4 20.2 80.3 17.2 42.7 18.6 13.6 54.0 10.8 14.7 21.4 24.4 23.2 21.0 9.2 40.2 53.4 16.7 15.9 13.5 14.1 22.4 15.0 30.7 19.8 26.7 0.0 14.5 18.8 57.2 36.1 17.9 25.4 83.0 13.4 27.5 20.0 19.7 PDP1 "PDH, PDP, PPM2A, PPM2C" ENSG00000164951 "Pyruvate dehyrogenase phosphatase catalytic subunit 1" Q9P0J1 8 93857807-93926068 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 80.0;Early spermatids: 144.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 8 "amygdala: 14.2;basal ganglia: 20.1;cerebral cortex: 41.7;hippocampal formation: 23.4;white matter: 18.5" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "GAMG: 117.8;hTERT-RPE1: 117.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018483, HPA019081, HPA021152" Uncertain Approved Nucleoplasm,Mitochondria,Cytosol Yes No "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Mitochondria, Cytosol" "HPA018483: AB_1855634, HPA019081: AB_1855633, HPA021152: AB_1855635" "prognostic unfavorable (8.61e-5)" "unprognostic (4.62e-1)" "unprognostic (8.79e-2)" "unprognostic (1.09e-1)" "unprognostic (9.46e-2)" "unprognostic (1.38e-1)" "unprognostic (1.59e-1)" "unprognostic (1.18e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (5.60e-4)" "unprognostic (1.71e-2)" "unprognostic (3.25e-1)" "prognostic favorable (8.42e-9)" "unprognostic (1.85e-1)" "unprognostic (1.84e-1)" "unprognostic (5.04e-2)" "unprognostic (1.67e-1)" 10.6 62.6 14.2 10.5 20.1 14.4 16.1 0.0 41.7 14.2 1.2 8.9 7.2 15.5 17.0 14.2 12.2 19.4 49.2 23.4 0.0 12.8 4.2 12.6 12.9 0.0 2.3 19.3 19.9 29.9 5.4 13.8 0.0 10.3 12.4 14.1 11.7 9.4 72.9 4.3 7.6 11.2 0.0 13.2 11.7 26.7 3.0 11.6 18.8 16.9 12.4 14.0 6.8 18.5 25.7 12.0 25.9 10.9 21.0 37.9 8.6 19.3 21.7 22.1 25.8 12.7 90.3 13.9 63.8 30.8 117.8 54.4 11.0 16.1 32.8 1.5 5.6 6.6 15.7 4.5 23.9 3.3 9.0 24.5 31.5 37.7 59.8 117.1 50.9 12.4 2.4 22.8 27.6 6.0 20.3 10.3 12.1 26.8 15.4 4.8 15.5 2.6 15.3 17.0 2.4 11.4 12.7 1.4 61.8 20.9 4.0 3.9 90.9 27.5 17.2 63.8 23.3 12.6 5.8 12.1 34.2 11.7 25.1 6.4 27.9 14.5 9.2 25.3 8.9 15.6 15.1 12.0 22.5 17.9 8.9 7.8 3.1 5.4 41.1 3.7 34.9 18.0 14.2 20.1 0.0 41.7 23.4 0.0 0.0 2.3 0.0 0.0 3.0 18.5 10.7 12.8 7.8 15.0 18.0 13.0 12.7 36.3 68.9 38.3 11.6 7.0 80.0 14.3 35.6 16.5 8.4 4.3 13.7 27.5 5.9 33.3 144.2 33.3 14.9 15.0 10.2 1.3 73.6 14.0 3.9 20.8 16.3 70.2 6.3 3.7 12.5 3.3 6.3 10.1 23.4 5.5 10.2 19.2 19.1 28.1 11.5 19.9 10.6 19.7 22.4 18.8 10.3 13.0 8.5 24.5 9.6 13.5 8.1 15.6 4.9 11.4 30.5 11.5 6.6 35.4 13.1 10.1 11.4 26.5 10.9 4.4 19.3 7.1 10.7 23.9 PDP2 "KIAA1348, PPM2B, PPM2C2" ENSG00000172840 "Pyruvate dehyrogenase phosphatase catalytic subunit 2" Q9P2J9 16 66878589-66895754 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 22.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019950, HPA062059" Approved Approved Mitochondria NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 11: Alveolar cells - Smell perception" Mitochondria "HPA019950: AB_1855156, HPA062059: AB_2684671" "unprognostic (8.42e-2)" "unprognostic (1.09e-1)" "unprognostic (1.19e-2)" "unprognostic (1.31e-1)" "unprognostic (2.31e-2)" "unprognostic (5.44e-2)" "unprognostic (1.17e-1)" "unprognostic (4.90e-3)" "unprognostic (1.57e-1)" "unprognostic (7.24e-2)" "unprognostic (1.03e-1)" "unprognostic (1.39e-1)" "prognostic favorable (9.75e-7)" "unprognostic (1.89e-1)" "unprognostic (5.10e-1)" "unprognostic (3.20e-1)" "unprognostic (6.15e-2)" 6.0 2.6 3.6 1.8 4.6 1.5 3.6 6.9 5.2 2.0 7.7 3.8 5.4 2.6 3.4 3.7 3.4 2.0 1.8 3.6 4.3 9.2 8.6 3.4 2.6 6.2 4.6 7.4 4.5 6.1 3.0 4.0 6.8 3.8 4.1 5.0 3.6 2.6 2.5 2.1 3.2 2.1 3.5 2.0 3.0 3.8 5.7 2.5 9.3 4.1 3.0 2.1 2.2 4.3 9.8 11.7 7.1 14.1 18.7 9.6 8.9 5.0 19.2 11.3 17.0 23.9 6.7 13.5 6.9 6.9 10.8 12.1 20.8 11.3 10.9 3.2 10.5 6.8 5.9 15.9 10.1 8.8 11.5 7.4 8.3 16.1 16.6 12.3 4.9 14.9 13.3 9.5 10.3 6.3 17.1 6.2 8.4 6.5 14.7 16.7 9.9 21.4 6.0 10.3 14.3 8.0 15.9 6.5 6.0 5.5 8.7 4.3 4.6 7.0 9.2 4.2 7.5 16.6 16.9 13.4 9.5 6.9 7.0 1.1 0.2 1.2 3.8 0.1 3.1 1.0 1.8 3.2 0.8 2.1 2.6 3.0 0.7 4.2 0.1 0.5 0.6 1.3 3.6 4.6 6.9 5.2 3.6 4.3 6.2 4.6 6.8 3.5 5.7 4.3 2.5 9.6 22.9 8.1 3.1 5.2 6.4 1.3 6.2 9.6 5.8 4.2 5.1 8.6 3.1 9.2 14.6 12.8 3.3 13.3 7.9 3.4 0.2 3.5 3.2 3.3 3.6 0.8 8.8 2.9 2.2 4.1 3.1 4.3 6.3 14.4 7.1 20.5 2.4 5.0 7.6 4.2 2.0 1.3 0.4 2.4 3.1 1.2 3.6 3.7 0.4 8.1 7.2 4.5 4.3 3.4 6.6 4.5 4.5 8.9 7.4 9.9 1.2 6.7 0.0 5.9 2.7 12.6 5.7 8.0 2.4 3.6 3.4 4.0 5.5 6.5 PDPR PDP3 ENSG00000090857 "Pyruvate dehydrogenase phosphatase regulatory subunit" Q8NCN5 16 70114332-70162537 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 54.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048092, HPA070386" Uncertain Approved Mitochondria NA NA "Cluster 46: Basophils - DNA binding" "Cluster 71: Testis - DNA repair" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Mitochondria "HPA048092: AB_2680261, HPA070386: AB_2686263" "unprognostic (8.30e-2)" "unprognostic (1.32e-1)" "unprognostic (7.91e-2)" "unprognostic (1.52e-1)" "unprognostic (2.57e-1)" "unprognostic (9.04e-3)" "unprognostic (6.81e-2)" "unprognostic (2.67e-1)" "unprognostic (1.41e-1)" "unprognostic (1.18e-2)" "unprognostic (2.55e-1)" "unprognostic (2.90e-1)" "prognostic favorable (8.36e-4)" "unprognostic (8.85e-2)" "unprognostic (1.96e-2)" "unprognostic (2.17e-1)" "unprognostic (6.24e-2)" 11.5 12.6 10.7 8.1 13.3 15.9 11.3 14.7 11.4 13.1 9.8 14.5 9.1 14.1 11.9 8.1 12.8 6.7 14.7 10.7 11.4 16.3 8.6 9.6 11.1 11.8 12.4 13.5 12.3 10.2 10.4 9.0 11.8 10.9 11.8 12.1 10.3 9.6 23.2 12.2 13.7 15.1 10.6 15.4 12.0 19.1 12.5 15.8 13.0 13.6 12.5 13.8 9.8 13.9 6.9 19.4 17.9 33.0 32.6 20.9 12.1 11.1 19.4 17.4 13.1 25.1 13.4 14.4 19.1 35.8 16.1 26.7 26.4 24.1 20.3 3.5 9.1 35.8 12.7 17.6 9.3 39.9 27.9 28.0 22.6 25.1 23.0 25.2 18.7 26.6 24.6 6.6 15.3 20.8 25.3 23.3 27.8 4.9 10.0 49.0 18.5 14.9 13.8 16.3 8.3 12.3 30.2 6.2 8.2 24.2 24.4 12.4 10.9 20.4 27.3 17.6 17.9 15.4 17.9 50.9 9.1 13.8 13.5 1.6 1.5 1.4 1.4 1.5 2.0 0.9 1.1 1.3 1.6 1.5 1.3 1.5 1.1 0.9 1.5 1.5 1.3 1.0 10.7 13.3 14.7 11.4 10.7 11.4 11.8 12.4 11.8 10.6 12.5 13.9 12.6 22.4 18.2 18.6 13.0 2.8 4.9 3.5 18.2 21.6 14.2 12.1 19.2 17.2 9.1 1.8 31.3 7.7 16.0 12.1 5.9 5.3 54.4 13.7 16.0 17.4 4.9 17.4 18.0 6.7 7.8 16.1 11.7 17.1 18.3 23.9 17.2 11.2 16.4 32.0 20.3 10.0 4.1 17.8 3.5 20.8 10.8 15.7 7.2 10.3 12.2 11.2 15.5 9.5 13.9 6.8 6.1 16.6 11.7 10.3 11.6 4.4 12.7 20.8 19.7 22.7 11.5 10.8 15.4 11.1 1.8 4.9 11.9 12.7 14.5 4.6 PDZRN4 "DKFZp434B0417, FLJ33777, IMAGE5767589, LNX4" ENSG00000165966 "PDZ domain containing ring finger 4" Q6ZMN7 12 41188320-41574745 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 10.9;seminal vesicle: 17.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 371.6;Inhibitory neurons: 125.6;Oligodendrocyte precursor cells: 561.9" "Cancer enhanced" "Detected in some" "thyroid cancer: 3.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 9 "U-266/70: 4.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042101 Enhanced Approved Mitochondria NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Mitochondria "HPA042101: AB_2732496" "unprognostic (6.74e-2)" "unprognostic (6.86e-2)" "unprognostic (3.82e-2)" "unprognostic (2.88e-2)" "unprognostic (1.49e-1)" "unprognostic (5.34e-2)" "unprognostic (2.48e-2)" "unprognostic (1.38e-2)" "unprognostic (8.19e-2)" "unprognostic (7.85e-3)" "unprognostic (1.69e-1)" "unprognostic (2.42e-1)" "unprognostic (7.44e-2)" "unprognostic (1.90e-3)" "unprognostic (1.80e-1)" "unprognostic (7.33e-2)" "unprognostic (1.41e-3)" 1.2 0.9 1.5 1.1 2.5 0.0 1.9 0.1 2.3 2.2 0.0 10.9 0.8 0.9 2.2 3.8 2.2 1.7 0.4 1.5 0.9 0.5 0.6 0.3 0.0 1.3 3.3 1.9 0.4 0.1 0.4 4.0 2.2 6.6 3.1 1.0 0.3 17.8 0.3 0.5 2.9 2.5 1.3 0.2 3.3 2.4 1.4 0.0 0.3 1.9 0.3 3.9 2.6 1.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 2.5 0.1 2.3 1.5 0.9 1.3 3.3 2.2 1.3 1.4 1.9 0.1 0.0 0.0 37.5 0.3 0.8 0.0 0.0 2.8 9.8 0.0 0.1 0.4 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.7 0.1 0.4 0.3 0.0 0.0 371.6 0.0 0.2 17.3 1.1 0.0 0.0 19.8 1.4 0.0 0.4 0.0 125.6 0.0 0.0 0.0 0.3 1.6 28.0 0.2 0.0 5.6 0.0 0.4 0.0 561.9 13.7 0.0 0.0 56.4 1.2 0.1 0.0 0.0 0.7 1.1 0.0 0.1 5.7 0.1 0.2 0.8 0.6 0.4 0.0 34.1 0.0 0.1 PEMT "PEMPT, PEMT2" ENSG00000133027 "Phosphatidylethanolamine N-methyltransferase" Q9UBM1 17 17505563-17591708 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 166.2;liver: 267.4" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 122.9;Hepatocytes: 220.1;Peritubular cells: 346.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042375, HPA073930" Approved Supported "Endoplasmic reticulum,Vesicles,Mitochondria,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 36: Stromal cells - Cell proliferation" "Endoplasmic reticulum, Mitochondria" "Vesicles, Cytosol" "HPA042375: AB_10796905, HPA073930: " "unprognostic (1.39e-2)" "unprognostic (3.43e-1)" "unprognostic (2.43e-2)" "prognostic favorable (6.77e-6)" "unprognostic (2.85e-1)" "unprognostic (7.14e-2)" "unprognostic (1.31e-1)" "unprognostic (1.28e-1)" "unprognostic (3.89e-1)" "unprognostic (3.41e-2)" "unprognostic (5.47e-3)" "unprognostic (2.67e-1)" "unprognostic (8.63e-3)" "unprognostic (2.08e-1)" "unprognostic (2.10e-1)" "unprognostic (6.66e-2)" "unprognostic (7.60e-2)" 71.6 33.9 13.2 5.2 13.6 9.2 92.7 16.3 20.0 47.4 12.7 13.6 15.0 36.9 166.2 26.8 26.5 5.4 24.5 13.0 15.2 30.2 267.4 25.8 5.2 14.9 15.3 27.9 32.2 13.3 24.7 7.3 16.8 30.8 3.4 2.8 27.1 24.0 29.5 34.3 13.7 6.8 15.1 12.8 19.5 40.8 14.2 5.6 33.5 10.7 4.5 21.1 24.2 17.2 34.3 64.7 16.5 43.4 34.6 23.8 25.1 21.6 19.0 28.5 22.4 38.2 22.6 29.8 38.1 21.9 21.6 39.9 24.6 12.8 7.2 22.2 86.9 14.8 33.2 55.4 38.4 13.5 21.4 24.9 26.7 19.2 29.1 9.7 15.7 41.3 14.6 12.3 12.9 66.0 23.9 24.2 23.2 65.5 52.4 22.2 26.7 27.5 24.1 12.5 16.7 39.5 15.3 10.1 39.2 31.5 15.6 5.1 13.9 28.1 28.2 47.4 18.9 17.0 12.1 5.5 25.9 18.5 23.6 1.9 41.1 2.1 16.9 39.0 24.8 23.5 22.2 21.5 30.5 28.3 17.2 19.4 3.1 29.3 28.0 27.7 22.4 21.3 13.2 13.6 16.3 20.0 13.0 15.2 14.9 15.3 16.8 15.1 14.2 17.2 38.1 16.0 17.5 4.9 12.4 18.2 21.0 27.9 39.3 4.5 33.0 45.1 15.5 11.5 24.9 27.6 0.0 19.5 5.9 9.3 17.6 33.3 2.9 21.8 122.9 18.5 68.8 17.1 5.4 38.5 21.6 30.4 8.2 23.8 12.7 52.4 10.4 220.1 23.5 5.0 6.8 30.9 24.4 13.7 12.2 14.9 94.8 11.2 21.4 3.7 5.7 34.7 2.1 9.5 4.0 25.7 10.8 346.8 15.3 35.1 21.7 32.3 14.2 6.1 6.6 20.0 23.6 21.0 24.9 39.5 18.2 14.6 12.5 49.3 24.1 23.8 PET100 C19orf79 ENSG00000229833 "PET100 cytochrome c oxidase chaperone" P0DJ07 19 7629793-7631956 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067288 Approved Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 16: Pancreatic endocrine cells - Mixed function" Mitochondria "HPA067288: AB_2732762" "unprognostic (7.02e-2)" "prognostic favorable (6.81e-4)" "unprognostic (1.57e-1)" "unprognostic (9.87e-3)" "unprognostic (2.14e-1)" "unprognostic (4.18e-2)" "unprognostic (1.70e-1)" "prognostic favorable (7.97e-4)" "unprognostic (4.89e-1)" "unprognostic (2.88e-3)" "unprognostic (2.49e-2)" "unprognostic (2.33e-2)" "unprognostic (4.09e-2)" "unprognostic (1.37e-1)" "unprognostic (1.25e-1)" "unprognostic (2.66e-2)" "prognostic favorable (2.44e-4)" 35.0 45.6 77.8 38.3 76.8 85.2 38.8 77.3 125.7 28.0 81.7 39.5 38.1 25.1 46.1 40.3 23.4 6.6 70.0 77.0 77.2 49.7 65.5 28.4 26.6 76.8 78.1 23.0 33.1 75.9 41.5 23.0 77.3 29.9 28.1 64.8 43.3 22.8 79.3 31.3 33.0 17.0 75.5 36.5 45.8 31.1 76.7 75.9 34.7 65.1 31.9 27.3 29.5 79.0 72.2 63.5 112.2 67.9 54.9 39.3 40.7 60.0 34.6 40.9 39.7 60.6 47.3 48.3 102.8 46.3 49.8 61.9 52.3 55.4 34.1 110.5 108.0 69.1 136.8 96.5 27.4 118.8 62.2 44.4 35.4 27.6 28.6 64.5 59.2 113.5 50.5 179.4 43.2 80.7 128.1 182.0 73.0 83.2 141.0 77.0 64.4 113.6 85.8 86.8 63.3 74.3 79.4 71.5 68.3 69.6 51.9 153.2 63.6 31.8 39.1 64.4 90.1 157.5 134.0 86.0 58.1 89.3 38.7 806.4 481.1 576.6 241.3 408.1 227.5 338.5 276.8 256.6 309.2 332.5 256.1 268.1 468.2 227.4 370.5 538.5 390.0 501.2 77.8 76.8 77.3 125.7 77.0 77.2 76.8 78.1 77.3 75.5 76.7 79.0 109.5 150.6 189.0 6.2 137.2 50.2 39.8 194.1 87.6 52.7 136.8 109.6 54.1 197.3 150.6 259.3 22.9 126.7 159.3 275.4 215.2 215.7 51.1 156.7 101.9 93.3 191.5 238.4 4.5 318.3 128.9 82.6 144.3 160.7 106.9 69.0 171.0 542.3 171.7 18.5 4.5 255.4 158.7 236.4 103.8 47.3 101.5 161.2 113.8 10.3 228.8 123.0 130.7 4.5 8.4 351.4 302.4 83.1 198.9 57.0 341.9 295.9 160.2 96.5 85.5 52.0 80.4 126.5 84.0 127.0 59.1 178.8 131.0 30.1 213.1 53.0 PGAP4 "C9orf125, MGC12992, TMEM246" ENSG00000165152 "Post-GPI attachment to proteins GalNAc transferase 4" Q9BRR3 9 101473170-101533537 "Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 16 "Cardiomyocytes: 52.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTCEpi: 25.5;hTERT-RPE1: 28.8;OE19: 48.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011318, HPA054041" Uncertain Approved Mitochondria NA Yes "Cluster 45: Intestine - Brush border" "Cluster 21: OE19 - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA011318: AB_2668482, HPA054041: AB_2682353" "unprognostic (2.58e-2)" "unprognostic (4.76e-2)" "unprognostic (5.52e-1)" "unprognostic (2.81e-3)" "unprognostic (2.72e-2)" "unprognostic (9.15e-2)" "unprognostic (1.20e-3)" "unprognostic (2.26e-1)" "unprognostic (1.11e-1)" "unprognostic (4.24e-1)" "unprognostic (3.51e-2)" "unprognostic (2.09e-1)" "prognostic favorable (1.55e-8)" "unprognostic (1.62e-1)" "unprognostic (1.91e-1)" "unprognostic (2.50e-1)" "unprognostic (9.16e-2)" 3.9 10.3 21.5 2.2 21.3 0.5 2.4 18.9 26.2 16.6 4.5 13.4 8.4 7.1 3.7 14.4 13.7 6.8 30.4 24.9 26.1 4.7 2.4 5.4 0.4 17.9 13.4 19.5 11.1 16.6 12.3 0.6 26.1 6.9 11.2 9.9 6.1 9.4 4.8 12.0 7.6 6.7 9.6 1.6 16.0 2.8 19.2 0.9 4.2 6.1 2.4 6.4 11.9 20.3 0.0 14.6 11.3 0.0 0.3 0.2 0.0 9.8 14.1 7.0 13.8 0.7 7.8 0.0 3.2 17.9 0.8 23.1 0.0 16.1 4.2 0.0 5.8 8.1 10.3 0.0 0.5 0.0 0.0 6.2 25.5 0.0 3.8 28.8 0.1 0.0 0.0 0.0 14.3 0.0 0.0 0.0 14.0 48.1 0.0 0.0 5.7 0.0 10.5 2.7 18.9 17.8 5.5 0.0 0.0 2.7 0.0 13.8 0.0 10.7 6.6 0.0 0.0 1.0 0.0 0.0 15.2 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.5 21.3 18.9 26.2 24.9 26.1 17.9 13.4 26.1 9.6 19.2 20.3 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.1 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PGF "D12S1900, PGFL, PIGF, PLGF, PlGF-2, SHGC-10760" ENSG00000119630 "Placental growth factor" P49763 14 74941834-74955626 "Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 50.5;thyroid gland: 52.5" "Group enriched" "Detected in many" 11 "Extravillous trophoblasts: 1604.4;Syncytiotrophoblasts: 2122.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "BEWO: 422.4;HUVEC TERT2: 199.1" "Low region specificity" "Detected in all" HPA041624 Approved Nucleoplasm,Mitochondria,Cytosol "Secreted to blood" No No 20800 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Mitochondria, Cytosol" "HPA041624: AB_10794522" "unprognostic (1.67e-2)" "unprognostic (4.62e-2)" "unprognostic (9.25e-3)" "unprognostic (1.34e-3)" "unprognostic (8.67e-3)" "unprognostic (2.41e-1)" "prognostic unfavorable (1.40e-4)" "unprognostic (7.26e-2)" "unprognostic (1.48e-1)" "unprognostic (4.45e-1)" "unprognostic (1.45e-2)" "unprognostic (3.51e-3)" "prognostic unfavorable (1.33e-6)" "unprognostic (2.52e-3)" "unprognostic (1.20e-1)" "unprognostic (3.49e-2)" "unprognostic (1.14e-1)" 11.8 4.9 7.4 7.8 7.6 0.1 11.3 7.3 11.7 22.4 20.2 7.0 2.4 7.6 1.4 10.0 21.8 5.9 18.8 8.7 20.6 8.1 6.0 7.2 6.4 9.5 15.7 6.4 4.9 8.4 5.5 50.5 9.3 19.3 2.0 1.2 10.5 10.3 9.9 15.7 12.5 7.8 7.0 3.3 4.8 3.2 8.6 3.9 52.5 5.9 3.3 13.6 14.8 7.8 1.4 1.5 1.3 1.3 2.0 0.2 422.4 4.0 3.6 1.8 2.2 10.9 0.6 0.3 9.1 2.8 0.2 0.5 1.8 19.2 1.6 0.2 2.4 0.0 0.1 11.3 1.5 0.2 11.0 4.7 4.5 7.5 1.8 0.5 199.1 0.0 0.0 0.1 55.6 0.9 0.0 0.5 2.1 0.1 3.4 0.2 51.3 0.0 0.5 1.0 31.0 17.0 0.0 0.8 7.7 25.0 0.1 0.5 40.6 0.3 10.2 0.1 17.0 0.4 0.2 0.7 6.3 0.5 0.5 0.0 0.0 0.2 0.4 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 7.4 7.6 7.3 11.7 8.7 20.6 9.5 15.7 9.3 7.0 8.6 7.8 32.4 9.6 4.6 1.0 1.0 24.6 10.3 111.4 34.7 1.3 8.9 16.0 3.6 0.0 26.0 0.0 14.6 83.8 2.4 2.0 0.0 2.7 0.1 1.1 3.3 169.4 7.1 2.7 0.1 0.5 1604.4 30.8 1.1 0.8 6.3 0.2 5.3 0.3 37.4 0.0 0.2 2.1 18.3 0.6 8.9 0.8 13.1 2.1 21.4 0.0 0.0 1.9 0.0 0.0 0.2 0.5 1.2 19.5 0.2 3.2 0.6 1.1 12.1 7.8 105.2 7.1 86.4 0.2 6.8 8.1 19.6 2122.6 3.0 3.0 2.3 5.8 PGM2L1 "BM32A, FLJ32029" ENSG00000165434 "Phosphoglucomutase 2 like 1" Q6PCE3 11 74330316-74398433 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Isomerase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 90.1;Exocrine glandular cells: 124.5;Pancreatic endocrine cells: 140.1;Respiratory ciliated cells: 95.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 16.6;LHCN-M2: 19.9;RH-30: 18.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056995, HPA060948" Enhanced Approved Mitochondria No No 140000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 1: Pancreatic cells - Digestion" Mitochondria "HPA056995: AB_2683305, HPA060948: AB_2684394" "unprognostic (7.44e-3)" "unprognostic (1.33e-1)" "unprognostic (7.28e-3)" "unprognostic (8.91e-2)" "unprognostic (6.16e-2)" "unprognostic (1.55e-1)" "unprognostic (7.16e-6)" "unprognostic (1.43e-1)" "unprognostic (1.95e-1)" "unprognostic (5.97e-3)" "unprognostic (1.70e-2)" "unprognostic (2.98e-1)" "unprognostic (9.33e-3)" "unprognostic (3.71e-1)" "unprognostic (1.97e-1)" "unprognostic (3.04e-1)" "unprognostic (1.03e-2)" 1.9 2.6 17.6 3.7 22.1 3.2 1.9 0.0 21.5 4.9 0.0 3.2 1.3 4.4 0.8 1.0 3.2 3.3 1.1 23.1 16.2 1.6 1.0 1.8 3.0 1.9 4.5 0.9 3.1 0.7 3.9 1.1 2.2 2.9 3.5 2.6 2.6 1.3 5.9 0.7 1.5 4.0 0.3 1.5 2.1 1.3 5.7 8.1 2.7 11.1 2.7 6.4 1.9 7.8 2.7 3.8 14.5 2.7 4.3 1.9 0.4 3.5 2.6 3.0 3.3 1.4 6.8 0.3 8.5 2.3 5.3 1.3 2.9 0.7 2.8 1.1 1.5 2.1 2.0 1.1 0.5 2.4 3.2 1.0 0.7 6.8 1.2 3.2 16.6 5.0 2.8 1.8 19.9 0.3 9.9 2.1 2.9 2.0 3.3 3.1 18.9 0.1 7.8 0.5 0.7 2.9 5.7 1.3 2.6 3.9 0.2 0.4 14.0 6.6 6.0 2.7 3.7 2.4 3.8 0.3 0.6 3.4 1.6 1.2 0.3 0.5 0.9 0.3 1.3 1.1 1.6 1.1 0.2 0.8 1.5 0.8 0.3 1.4 0.2 0.8 3.9 0.5 17.6 22.1 0.0 21.5 23.1 16.2 1.9 4.5 2.2 0.3 5.7 7.8 19.6 6.4 6.4 8.5 20.9 7.6 41.2 14.3 10.8 23.9 26.5 19.4 7.3 17.2 30.2 9.2 16.7 0.6 17.6 13.8 5.9 37.4 14.1 28.1 23.5 32.1 11.9 47.5 90.1 124.5 5.3 21.0 7.1 25.5 8.2 16.1 29.3 1.0 5.4 8.4 64.8 16.2 18.3 23.0 21.6 3.6 2.5 9.9 16.0 20.6 4.6 4.4 12.3 14.6 7.1 140.1 9.3 3.8 13.4 50.4 4.2 5.3 95.4 11.0 26.3 21.3 16.7 34.2 21.2 9.0 5.3 0.1 25.0 8.8 20.9 55.6 PHYKPL "AGXT2L2, MGC15875" ENSG00000175309 "5-phosphohydroxy-L-lysine phospho-lyase" Q8IUZ5 5 178208471-178232802 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Lyase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036461, HPA063608" Approved Approved Mitochondria Yes No 160000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 34: Non-specific - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" Mitochondria "HPA036461: AB_10670717, HPA063608: AB_2685059" "unprognostic (3.29e-3)" "unprognostic (2.60e-1)" "unprognostic (5.51e-2)" "unprognostic (9.75e-2)" "unprognostic (1.28e-1)" "unprognostic (1.47e-1)" "unprognostic (1.24e-1)" "unprognostic (1.06e-2)" "unprognostic (1.68e-2)" "unprognostic (3.29e-1)" "unprognostic (5.38e-2)" "unprognostic (1.02e-3)" "prognostic unfavorable (3.82e-5)" "unprognostic (3.66e-2)" "unprognostic (1.55e-1)" "unprognostic (1.02e-1)" "unprognostic (2.41e-3)" 23.2 10.6 7.4 16.4 8.2 14.9 14.0 6.8 8.6 12.3 8.3 23.9 20.7 14.3 15.8 11.1 13.9 14.4 15.5 6.7 8.3 17.5 42.2 15.8 24.5 11.4 8.3 12.5 15.6 13.7 5.2 16.3 10.0 13.7 30.8 3.4 13.8 12.0 19.6 10.7 24.8 18.5 7.6 17.2 15.5 5.9 9.5 25.1 19.7 18.7 23.6 13.7 9.6 11.7 9.6 3.8 9.0 3.6 21.6 17.4 13.9 5.6 6.2 7.6 11.8 9.7 11.7 13.0 18.4 17.6 9.7 6.2 7.7 14.3 8.5 24.0 8.7 15.6 18.0 7.1 35.1 9.2 11.4 19.6 15.0 9.3 22.4 14.9 24.9 18.6 11.8 26.7 11.3 13.1 13.1 5.5 1.9 11.5 12.4 9.1 4.3 25.0 13.4 8.3 5.7 5.4 9.2 5.2 9.4 10.2 5.5 7.4 9.9 7.8 7.0 5.1 6.2 18.8 5.5 7.2 2.2 9.2 5.2 16.7 41.7 36.9 20.3 46.8 20.4 28.4 22.2 22.9 53.4 26.3 27.3 22.2 9.2 23.7 47.2 70.9 28.6 33.2 7.4 8.2 6.8 8.6 6.7 8.3 11.4 8.3 10.0 7.6 9.5 11.7 23.1 19.2 14.3 31.6 63.0 10.7 43.1 16.1 25.0 21.9 17.2 14.5 17.4 37.1 13.0 23.9 25.0 18.4 72.5 96.1 19.6 24.6 21.7 13.2 27.7 26.2 19.2 30.7 20.7 18.6 20.2 33.4 76.9 13.8 12.7 38.4 31.1 30.1 31.7 15.2 17.9 40.8 6.1 37.1 22.9 55.3 42.6 43.3 24.9 36.5 61.1 25.0 70.0 29.1 45.2 15.1 64.5 25.2 51.4 30.3 119.2 43.1 13.6 26.4 13.1 34.5 23.6 37.2 25.9 14.6 10.4 22.0 58.9 36.3 39.2 36.6 PILRB "FDFACT1, FDFACT2" ENSG00000121716 "Paired immunoglobin like type 2 receptor beta" Q9UKJ0 7 100352176-100367733 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 134.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 221.1;neutrophil: 141.8" "Group enriched" "Detected in all" 8 "granulocytes: 221.1;monocytes: 75.5" "Cell line enhanced" "Detected in all" "SK-BR-3: 344.6" HPA026750 Approved Approved Mitochondria "Intracellular and membrane" NA Yes "Cluster 45: Eosinophils - Innate immune response" "Cluster 43: Testis - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" Mitochondria "HPA026750: AB_10670828" "unprognostic (8.33e-3)" "unprognostic (9.31e-2)" "unprognostic (1.32e-2)" "unprognostic (9.15e-2)" "unprognostic (1.02e-1)" "unprognostic (1.30e-1)" "unprognostic (3.62e-2)" "unprognostic (3.17e-1)" "unprognostic (1.20e-1)" "unprognostic (8.76e-2)" "unprognostic (2.54e-2)" "unprognostic (6.27e-2)" "prognostic unfavorable (1.42e-4)" "unprognostic (4.85e-3)" "unprognostic (1.66e-1)" "unprognostic (4.40e-2)" "unprognostic (3.35e-3)" 63.2 89.0 72.9 71.0 75.0 71.7 77.6 104.3 86.3 87.0 90.9 65.8 66.1 62.9 67.6 47.2 83.8 52.2 47.7 75.5 70.8 118.8 125.0 43.9 83.7 71.8 70.8 82.1 91.7 58.3 182.0 32.9 71.5 102.7 57.4 66.8 66.4 58.0 78.7 90.1 75.9 42.3 64.2 113.5 68.7 157.5 74.3 59.0 122.9 34.3 65.7 61.9 56.2 78.1 62.5 51.4 57.9 100.7 63.0 14.4 56.2 37.0 16.5 25.7 24.9 36.5 70.3 50.3 68.0 19.0 45.7 65.1 32.3 38.9 17.5 41.6 47.3 46.5 204.8 32.2 14.0 47.4 116.0 18.1 44.8 34.8 70.2 31.9 21.8 73.6 50.7 118.9 18.3 83.9 74.8 243.3 25.2 51.7 26.9 43.3 16.9 51.6 116.4 100.3 53.8 38.5 31.2 344.6 45.7 61.7 60.5 72.3 52.4 90.8 57.9 58.8 48.7 71.2 98.6 61.8 25.5 69.4 54.6 21.2 35.6 221.1 10.7 59.2 6.7 0.6 1.3 7.1 17.8 1.6 1.2 2.6 141.8 17.9 75.5 0.5 0.6 25.7 72.9 75.0 104.3 86.3 75.5 70.8 71.8 70.8 71.5 64.2 74.3 78.1 22.8 38.5 45.9 0.0 25.3 15.7 18.1 17.1 11.4 44.7 32.9 33.7 1.1 44.3 32.2 14.7 68.8 12.9 49.5 12.3 1.9 7.6 18.4 43.1 17.5 19.8 29.4 7.4 0.0 5.6 12.1 13.4 36.2 57.2 25.2 26.0 24.3 77.7 10.0 75.7 0.0 21.2 22.4 16.0 16.6 13.6 74.0 11.7 19.6 0.0 10.0 19.0 134.9 0.0 0.0 7.4 16.2 51.1 14.5 17.9 20.3 4.9 40.3 64.9 26.3 18.2 14.3 49.4 10.2 10.5 13.5 15.7 37.0 23.5 22.4 16.7 PIWIL4 "FLJ36156, HIWI2, Miwi2" ENSG00000134627 "Piwi like RNA-mediated gene silencing 4" Q7Z3Z4 11 94543840-94621421 "Predicted intracellular proteins" "Differentiation, Meiosis, RNA-mediated gene silencing, Spermatogenesis, Translation regulation" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.3" "Cell type enhanced" "Detected in many" "Intestinal goblet cells: 8.7;Spermatogonia: 12.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "NB-4: 93.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA036587, HPA036588, HPA057508" Enhanced Supported Nucleoplasm,Mitochondria NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 24: NB-4 - Immune response" "Cluster 27: Mucus-secreting cells - Mucin production" "Nucleoplasm, Mitochondria" "HPA036587: AB_2732473, HPA036588: AB_10673502, HPA057508: AB_2683452" "unprognostic (1.43e-1)" "unprognostic (9.46e-2)" "unprognostic (2.59e-3)" "unprognostic (2.22e-3)" "unprognostic (3.16e-2)" "unprognostic (1.07e-3)" "unprognostic (1.96e-2)" "unprognostic (5.18e-2)" "unprognostic (1.41e-1)" "unprognostic (1.70e-1)" "unprognostic (6.17e-2)" "unprognostic (2.68e-1)" "unprognostic (1.21e-4)" "unprognostic (6.89e-2)" "unprognostic (1.68e-1)" "unprognostic (2.50e-1)" "unprognostic (2.80e-2)" 3.3 1.1 5.5 2.8 5.3 24.3 3.6 4.9 5.0 4.4 3.4 5.8 5.8 3.7 2.3 1.6 3.6 4.6 2.8 5.6 4.7 3.2 1.3 2.7 3.9 4.5 4.4 3.4 11.3 0.4 2.2 2.0 4.5 2.5 6.0 6.7 8.8 2.6 1.0 1.7 6.3 2.0 4.5 3.7 5.1 13.3 4.9 3.0 2.0 1.0 2.7 3.3 3.0 5.4 0.2 0.1 0.4 0.0 6.6 4.3 0.5 0.5 0.3 0.2 0.9 0.7 0.6 0.0 0.4 2.8 0.2 0.0 0.9 0.0 0.2 2.7 0.3 0.2 0.6 0.0 2.5 6.5 0.1 1.5 0.0 0.5 0.0 0.1 0.1 0.5 0.3 0.0 1.1 0.4 0.3 93.2 0.1 9.2 0.6 0.4 0.0 0.0 2.1 0.0 0.4 0.3 0.4 0.9 0.4 0.3 0.0 20.7 1.2 0.4 0.1 0.1 0.1 0.1 0.0 0.0 0.1 9.9 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.2 5.5 5.3 4.9 5.0 5.6 4.7 4.5 4.4 4.5 4.5 4.9 5.4 1.1 0.0 0.5 3.3 0.2 1.3 0.2 0.4 0.0 0.6 1.3 1.3 3.5 7.2 1.4 0.0 0.0 4.0 0.2 4.1 1.9 6.2 4.7 0.7 0.7 0.6 0.0 0.4 5.4 2.0 0.5 1.6 7.7 1.3 0.0 0.9 0.7 0.0 1.7 0.0 4.9 8.7 0.0 3.0 1.7 2.1 0.3 1.7 0.0 3.7 2.0 0.7 1.0 5.0 6.0 3.0 4.9 1.2 0.1 0.5 4.4 0.6 1.7 3.3 0.0 2.2 1.3 1.2 12.0 0.6 0.1 1.0 0.3 0.3 5.3 0.1 PJVK DFNB59 ENSG00000204311 Pejvakin Q0ZLH3 2 178451346-178462102 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Hearing "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 20.7" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Alveolar cells type 2: 9.1;Distal tubular cells: 3.9;Granulosa cells: 6.1;Theca cells: 4.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "plasmacytoid DC: 2.8" "Lineage enriched" "Detected in single" 5 "dendritic cells: 2.8" "Cell line enhanced" "Detected in many" "SuSa: 6.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042621 Approved Mitochondria No No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 68: Epididymis - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA042621: AB_10797503" "unprognostic (4.01e-2)" "unprognostic (4.28e-2)" "unprognostic (1.58e-2)" "unprognostic (2.64e-1)" "unprognostic (7.21e-3)" "unprognostic (9.36e-2)" "unprognostic (1.22e-1)" "unprognostic (1.14e-1)" "unprognostic (8.60e-3)" "unprognostic (4.57e-2)" "unprognostic (1.90e-3)" "unprognostic (9.13e-2)" "prognostic unfavorable (8.92e-4)" "unprognostic (1.22e-1)" "unprognostic (1.47e-1)" "unprognostic (2.41e-2)" "unprognostic (8.06e-3)" 3.0 1.8 6.9 1.3 7.2 1.4 4.8 6.9 10.7 2.7 6.9 1.9 1.2 3.9 7.3 1.2 2.8 2.9 1.4 7.0 7.0 3.2 2.8 1.5 1.9 7.6 7.3 7.1 1.3 1.1 4.1 1.2 7.5 2.8 1.2 6.4 2.7 3.0 3.5 4.2 1.4 2.0 7.3 1.4 1.2 20.7 7.1 1.2 2.5 0.9 1.7 1.9 1.4 7.7 0.2 1.8 2.3 1.9 3.0 3.1 1.2 1.5 1.4 1.2 2.0 0.7 3.1 2.1 1.5 0.9 1.0 0.9 1.7 1.0 0.9 0.7 0.6 0.7 2.9 0.4 3.0 0.6 0.2 3.2 2.2 1.4 3.2 3.8 1.5 4.1 0.4 1.3 1.5 0.5 2.1 1.3 2.8 0.2 0.8 2.7 1.7 1.3 2.0 1.0 1.6 1.3 0.5 0.3 0.6 6.8 0.7 0.7 1.0 1.5 0.6 0.4 0.1 4.3 2.8 0.7 0.7 1.1 0.6 0.1 0.1 0.0 0.1 0.1 0.2 0.3 0.2 0.1 0.0 0.5 0.5 0.3 0.4 0.2 0.0 2.8 0.0 0.0 6.9 7.2 6.9 10.7 7.0 7.0 7.6 7.3 7.5 7.3 7.1 7.7 1.6 6.4 9.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.0 2.4 0.0 0.0 1.8 1.8 0.0 1.1 0.5 0.0 3.9 1.4 0.0 1.8 2.6 0.4 0.0 0.0 0.0 0.9 0.5 1.4 0.0 1.6 0.0 6.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 2.6 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.6 4.7 0.0 0.0 PLAAT2 "FLJ20556, HRASLS2, PLAAT-2" ENSG00000133328 "Phospholipase A and acyltransferase 2" Q9NWW9 11 63552770-63563379 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 67.9" "Cell type enhanced" "Detected in single" "dendritic cells: 2.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 8 "memory B-cell: 17.3;naive B-cell: 8.2" "Lineage enriched" "Detected in many" 10 "B-cells: 17.3" "Cell line enriched" "Detected in some" 8 "U-266/70: 128.9" HPA058997 Approved Approved Mitochondria NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Mitochondria "HPA058997: AB_2683874" "unprognostic (4.76e-2)" "prognostic favorable (6.87e-4)" "unprognostic (1.20e-1)" "unprognostic (3.07e-2)" "unprognostic (1.43e-1)" "unprognostic (1.43e-1)" "unprognostic (1.82e-1)" "unprognostic (1.53e-1)" "unprognostic (9.69e-2)" "unprognostic (3.91e-3)" "prognostic unfavorable (5.27e-5)" "unprognostic (1.56e-1)" "unprognostic (2.29e-1)" "unprognostic (1.38e-2)" "unprognostic (2.51e-1)" "unprognostic (2.43e-1)" "unprognostic (1.57e-2)" 0.3 0.0 0.6 0.8 0.6 0.1 9.1 0.5 0.9 0.9 0.3 11.2 67.9 0.3 1.2 1.5 4.7 0.6 0.2 0.5 0.5 8.6 4.6 3.6 0.3 0.7 0.6 0.2 0.0 0.0 0.2 0.2 0.6 0.4 13.7 0.0 0.9 0.5 0.0 0.3 42.5 0.3 0.5 0.7 12.4 0.5 0.6 0.3 0.9 0.0 0.3 1.3 0.2 1.1 0.4 1.7 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.4 0.1 0.3 15.6 0.0 0.9 0.0 0.4 1.0 0.6 0.2 0.1 0.2 0.0 0.1 1.0 0.1 0.2 0.0 0.1 0.1 1.2 0.3 0.0 0.7 0.0 0.0 0.0 6.7 0.0 0.0 0.2 0.3 0.1 8.7 1.9 0.0 0.0 1.5 0.6 0.0 0.0 0.2 0.1 4.0 0.0 0.1 2.2 0.1 0.0 0.0 0.0 0.1 0.0 128.9 16.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.9 17.3 0.2 1.0 0.1 8.2 0.2 0.7 0.1 1.6 0.0 0.9 0.0 3.9 0.6 0.6 0.5 0.9 0.5 0.5 0.7 0.6 0.6 0.5 0.6 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 PLD5 FLJ40773 ENSG00000180287 "Phospholipase D family member 5" Q8N7P1 1 242082986-242524697 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "brain: 16.2;choroid plexus: 52.8" "Group enriched" "Detected in some" 6 "Inhibitory neurons: 319.5;Oligodendrocyte precursor cells: 127.6;Oligodendrocytes: 226.8" "Cancer enhanced" "Detected in single" "glioma: 0.7" "Region enriched" "Detected in all" 5 "cerebellum: 16.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 3.0;AF22: 10.3;HDLM-2: 5.3;SH-SY5Y: 2.9;U-2 OS: 3.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028389, HPA050367" Approved Vesicles,Mitochondria,Cytosol No No "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "Vesicles, Cytosol" "HPA028389: AB_10602145, HPA050367: AB_2681105" "unprognostic (5.20e-2)" "unprognostic (1.05e-1)" "unprognostic (9.14e-2)" "unprognostic (1.25e-1)" "unprognostic (2.27e-2)" "unprognostic (1.32e-2)" "unprognostic (8.77e-2)" "unprognostic (4.36e-1)" "unprognostic (1.95e-1)" "unprognostic (2.08e-3)" "unprognostic (2.71e-1)" "unprognostic (2.16e-5)" "unprognostic (2.79e-2)" "unprognostic (4.46e-1)" "unprognostic (3.44e-3)" "unprognostic (2.18e-1)" 0.4 1.7 1.7 0.0 2.9 0.0 0.4 16.2 2.5 0.6 52.8 0.2 0.0 1.1 0.2 0.4 1.1 0.1 0.1 3.4 2.5 0.4 0.0 0.2 1.1 2.9 2.6 2.1 1.0 0.2 2.4 0.4 2.8 0.8 0.1 0.3 0.7 3.0 0.2 0.1 0.1 0.9 2.0 0.7 0.3 1.5 2.2 0.4 0.2 0.0 0.4 0.1 0.3 2.7 0.0 3.0 10.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.4 0.0 5.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.2 0.0 0.0 0.0 0.0 0.3 2.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2.9 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 2.9 16.2 2.5 3.4 2.5 2.9 2.6 2.8 2.0 2.2 2.7 0.1 0.0 0.0 7.8 0.2 0.1 0.0 0.0 1.2 0.5 0.0 1.7 1.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 9.1 2.9 0.6 0.3 0.0 0.0 35.5 0.0 0.0 3.1 0.0 8.2 0.0 0.7 0.0 0.0 0.0 3.3 319.5 0.2 0.0 0.0 0.0 21.0 5.0 0.1 0.0 5.6 0.0 0.4 0.0 127.6 226.8 0.0 0.0 2.2 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 1.5 1.2 0.6 0.2 0.1 0.3 0.0 0.0 0.0 0.1 PLEKHJ1 FLJ10297 ENSG00000104886 "Pleckstrin homology domain containing J1" Q9NW61 19 2230084-2237704 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 356.3;Proximal enterocytes: 372.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048989 Approved Approved Mitochondria No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA048989: AB_2680590" "unprognostic (5.11e-1)" "unprognostic (4.84e-3)" "unprognostic (2.33e-1)" "unprognostic (9.82e-2)" "unprognostic (1.38e-1)" "unprognostic (7.83e-2)" "unprognostic (2.03e-3)" "unprognostic (2.89e-3)" "unprognostic (1.51e-1)" "unprognostic (1.71e-1)" "unprognostic (9.03e-3)" "unprognostic (3.49e-2)" "prognostic favorable (1.10e-5)" "prognostic favorable (6.99e-4)" "unprognostic (5.67e-2)" "unprognostic (1.15e-1)" "unprognostic (6.26e-3)" 43.4 64.1 41.8 26.4 39.0 38.3 40.5 40.4 51.3 38.8 40.6 109.2 105.2 33.6 18.0 61.3 30.0 19.5 77.6 40.2 39.8 101.1 78.7 42.0 39.3 41.6 41.7 44.1 94.1 14.7 36.4 19.7 43.6 43.4 34.0 4.7 52.2 14.3 88.9 51.7 101.5 12.2 40.2 61.4 99.7 68.0 45.3 27.8 69.2 33.2 24.0 40.8 39.7 38.8 93.9 38.2 68.2 83.0 21.8 28.3 40.3 51.6 24.1 54.1 48.9 98.1 43.1 88.4 42.1 35.6 34.7 71.6 65.4 34.0 16.1 90.8 83.7 46.3 44.5 129.0 34.7 98.6 68.9 41.6 34.2 25.8 23.1 21.5 34.9 75.4 99.5 101.0 39.8 61.3 97.0 88.0 122.6 55.6 52.1 114.7 47.5 108.8 55.7 92.0 170.2 94.1 32.6 58.7 104.5 27.3 78.6 98.2 36.6 23.0 68.7 69.7 56.7 147.3 97.2 101.3 67.4 94.8 30.1 88.2 76.4 129.6 86.9 98.2 77.1 118.8 85.9 91.8 80.8 143.2 69.0 67.2 66.1 53.8 108.3 159.0 112.6 97.2 41.8 39.0 40.4 51.3 40.2 39.8 41.6 41.7 43.6 40.2 45.3 38.8 25.9 38.5 21.1 9.8 67.0 34.8 54.6 61.5 20.5 22.0 60.0 68.1 40.0 87.2 37.8 46.0 16.7 89.8 65.8 356.3 164.4 121.1 68.5 33.2 33.4 26.7 54.0 39.8 12.1 179.5 99.3 46.0 121.8 35.2 18.4 117.1 25.7 49.2 95.4 25.2 11.7 228.5 95.6 43.9 33.3 115.6 47.2 48.1 30.2 9.4 74.7 31.9 65.9 12.1 7.6 146.6 233.3 35.3 49.0 82.2 372.5 148.4 29.1 22.7 32.9 18.9 47.5 93.7 100.7 47.2 42.6 47.7 52.6 81.4 254.1 58.4 PLK2 SNK ENSG00000145632 "Polo like kinase 2" Q9NYY3 5 58453982-58460139 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 380.7;Extravillous trophoblasts: 257.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "NK-cell: 9.1" "Lineage enriched" "Detected in many" 4 "NK-cells: 9.1" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 1060.6;T-47d: 396.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009624, HPA069329" Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Mitochondria, Cytosol" "CAB009624: AB_2167745, HPA069329: " "unprognostic (4.82e-2)" "unprognostic (1.08e-2)" "unprognostic (2.38e-1)" "unprognostic (6.51e-2)" "prognostic unfavorable (7.75e-4)" "unprognostic (1.22e-1)" "unprognostic (2.55e-2)" "unprognostic (1.03e-2)" "unprognostic (2.44e-2)" "unprognostic (1.06e-2)" "unprognostic (1.01e-1)" "unprognostic (3.11e-1)" "prognostic unfavorable (2.08e-4)" "unprognostic (6.56e-2)" "unprognostic (1.43e-1)" "unprognostic (3.46e-1)" "unprognostic (1.95e-3)" 24.3 8.4 25.6 7.4 35.7 9.3 40.6 6.4 31.2 37.9 16.4 11.8 9.3 29.0 9.3 35.5 21.0 32.1 54.7 44.4 10.4 15.7 31.1 32.3 7.2 8.1 12.3 19.3 23.4 5.9 6.3 47.6 8.4 17.7 14.6 2.1 42.9 10.5 7.4 47.3 12.9 26.6 7.3 83.6 10.4 38.1 11.8 7.2 18.0 13.6 7.6 29.8 32.1 16.8 131.1 115.6 38.3 3.1 19.9 31.9 15.1 27.1 44.8 86.3 49.8 8.6 112.1 0.0 176.3 95.2 208.3 159.8 1.7 61.5 75.6 0.3 3.5 0.0 50.8 9.7 106.1 0.6 3.6 18.7 82.0 33.3 90.9 1060.6 175.4 0.0 0.1 4.4 169.8 47.5 0.3 0.2 7.6 12.4 18.5 6.3 106.5 0.0 221.6 25.4 2.3 5.1 82.4 16.0 76.0 66.1 396.9 2.0 231.9 24.3 63.8 11.0 217.8 0.1 0.3 0.3 18.8 0.3 110.7 2.2 0.5 1.9 0.1 1.2 0.0 0.8 0.5 0.0 2.2 0.6 0.9 0.4 1.5 9.1 0.5 1.5 0.4 0.4 25.6 35.7 6.4 31.2 44.4 10.4 8.1 12.3 8.4 7.3 11.8 16.8 144.6 19.2 15.8 5.9 23.4 141.7 194.1 116.1 380.7 3.8 108.5 203.7 128.9 30.0 134.9 18.4 4.2 66.5 22.7 66.3 9.8 109.8 10.9 132.7 67.8 178.7 84.3 2.7 44.3 77.9 257.3 107.8 136.6 165.4 9.5 4.1 89.3 7.7 14.9 0.0 22.8 39.9 124.1 8.1 19.3 5.0 12.8 39.5 24.9 15.9 3.2 3.3 0.0 3.5 4.9 103.2 44.6 10.9 8.2 76.1 38.5 5.5 31.6 2.9 0.0 74.0 106.6 65.1 10.4 184.9 103.4 129.8 21.2 7.4 45.6 63.1 PLXNC1 "CD232, VESPR" ENSG00000136040 "Plexin C1" O60486 12 94148577-94307675 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 57.0;Macrophages: 62.5;Melanocytes: 96.0;monocytes: 53.8" "Cancer enhanced" "Detected in all" "melanoma: 24.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 16.4" "Group enriched" "Detected in all" 4 "granulocytes: 16.4;monocytes: 8.6" "Cell line enhanced" "Detected in many" "HAP1: 33.3;Karpas-707: 25.8;SK-MEL-30: 41.4;U-266/70: 64.3;U-266/84: 73.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066899 Approved Mitochondria NA NA 150000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Mitochondria "HPA066899: AB_2685743" "unprognostic (1.49e-1)" "unprognostic (4.01e-2)" "unprognostic (5.60e-2)" "unprognostic (1.99e-1)" "unprognostic (2.33e-1)" "unprognostic (3.24e-2)" "unprognostic (4.67e-3)" "unprognostic (2.80e-2)" "unprognostic (3.49e-1)" "unprognostic (4.64e-2)" "unprognostic (1.78e-2)" "unprognostic (2.38e-1)" "unprognostic (4.02e-2)" "unprognostic (5.33e-3)" "unprognostic (3.19e-2)" "unprognostic (6.85e-3)" "unprognostic (5.48e-2)" 6.1 8.8 6.4 20.5 7.1 17.4 4.7 8.9 7.5 8.5 1.9 5.7 4.1 7.0 2.7 3.8 4.8 10.2 1.9 7.1 15.9 4.0 2.5 11.4 16.2 5.3 12.7 14.8 2.4 0.9 4.1 9.4 4.7 2.3 6.5 2.2 2.3 4.5 4.0 8.3 5.5 6.9 4.2 19.8 4.5 15.2 18.6 5.7 3.4 4.1 13.0 9.5 3.8 8.7 1.1 0.4 2.7 0.5 1.5 1.2 0.4 1.3 1.8 1.7 5.1 9.1 0.1 21.8 0.1 2.0 1.6 0.1 33.3 1.4 1.2 15.3 0.7 1.2 0.6 6.1 17.7 4.5 7.2 17.7 0.0 1.9 0.8 2.3 0.0 2.0 0.6 25.8 0.5 0.3 1.0 2.4 5.5 0.2 1.2 3.6 1.0 12.1 0.1 1.7 2.2 1.6 0.3 0.2 41.4 6.3 0.1 3.7 0.7 0.6 2.3 0.2 0.8 64.3 73.3 1.4 0.4 11.7 1.4 0.0 3.6 15.1 1.6 6.1 1.7 2.6 1.7 1.9 2.9 1.7 1.6 1.6 16.4 1.1 8.6 1.1 1.3 2.0 6.4 7.1 8.9 7.5 7.1 15.9 5.3 12.7 4.7 4.2 18.6 8.7 4.9 3.2 2.4 9.8 17.9 6.1 0.3 0.3 1.2 3.6 3.2 2.5 8.1 1.5 0.2 0.0 0.0 0.2 5.6 1.2 1.9 0.2 9.4 3.2 14.9 4.3 19.8 26.1 36.1 0.5 0.2 16.0 1.1 1.6 16.5 29.8 6.1 1.6 18.8 0.0 57.0 1.8 0.0 39.4 13.8 6.2 1.5 62.5 96.0 40.3 53.8 0.3 3.1 34.2 12.6 0.3 1.8 3.4 24.4 0.2 0.1 3.4 2.3 0.5 6.6 2.8 2.5 3.0 1.1 0.7 1.6 0.1 9.4 4.8 1.9 0.3 PNPLA3 "adiponutrin, ADPN, C22orf20, dJ796I17.1, FLJ22012, iPLA2epsilon" ENSG00000100344 "Patatin like phospholipase domain containing 3" Q9NST1 22 43923792-43964488 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Disease variant, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 31.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 35.9;Cone photoreceptor cells: 18.8;Hepatocytes: 42.3;Rod photoreceptor cells: 37.3" "Cancer enhanced" "Detected in many" "liver cancer: 4.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 16.7;LHCN-M2: 19.3" "Region enhanced" "Detected in many" "cerebellum: 12.2" "Not detected" "Not detected" HPA058058 Approved Approved Nucleoli,Mitochondria,Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoli "Mitochondria, Cytosol" "HPA058058: AB_2683590" "unprognostic (4.74e-3)" "unprognostic (4.52e-2)" "unprognostic (1.76e-1)" "unprognostic (2.31e-1)" "unprognostic (1.36e-2)" "unprognostic (1.89e-1)" "unprognostic (8.93e-2)" "unprognostic (1.02e-1)" "unprognostic (2.63e-1)" "unprognostic (2.93e-1)" "unprognostic (2.33e-2)" "unprognostic (1.05e-1)" "unprognostic (1.39e-3)" "unprognostic (2.52e-3)" "unprognostic (5.91e-2)" "unprognostic (2.02e-2)" "unprognostic (1.01e-1)" 2.6 0.2 0.6 0.5 0.8 0.1 1.6 0.1 1.2 0.6 5.9 0.1 0.8 0.3 0.1 0.2 0.9 0.4 0.2 1.2 0.7 4.5 31.0 0.8 0.3 1.7 1.8 0.3 0.0 0.2 0.0 0.3 2.0 0.0 0.1 6.4 0.7 0.0 1.7 5.8 0.5 0.0 0.2 0.4 0.2 0.4 1.3 0.1 0.1 0.1 0.2 0.0 0.3 0.6 5.1 1.6 16.7 6.8 4.6 5.2 0.5 3.1 1.8 4.1 8.8 5.0 9.0 0.0 2.5 5.2 2.4 4.3 10.6 5.0 3.4 0.0 0.9 0.3 4.5 9.4 7.5 0.0 0.3 6.0 3.8 13.2 0.6 7.0 0.5 0.2 0.0 0.0 19.3 0.7 0.3 0.0 11.5 0.6 0.0 0.1 8.9 0.2 1.7 0.2 1.5 0.1 3.4 1.4 4.8 2.9 5.3 5.8 0.6 1.6 4.9 0.1 0.1 0.1 0.0 0.0 14.3 0.1 6.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.6 0.8 0.1 1.2 1.2 0.7 1.7 1.8 2.0 0.2 1.3 0.6 0.4 0.0 0.0 4.2 0.2 0.4 0.5 2.4 0.0 35.9 0.5 0.1 1.3 10.0 1.4 0.0 18.8 0.0 0.2 0.2 0.0 0.4 0.0 1.5 0.5 0.4 1.8 0.0 1.9 0.0 0.1 0.5 0.0 3.6 0.0 1.9 0.7 42.3 0.7 0.0 1.2 0.8 0.0 2.8 0.3 0.3 0.3 0.9 1.8 0.0 0.0 1.1 0.0 0.0 0.8 2.6 0.0 0.7 0.0 0.7 0.4 5.0 0.1 37.3 0.0 1.0 0.8 0.6 0.6 0.0 0.1 0.0 0.2 1.6 0.4 0.4 POLDIP2 "DKFZP586F1524, PDIP38" ENSG00000004142 "DNA polymerase delta interacting protein 2" Q9Y2S7 17 28346633-28357527 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 189.8;Proximal tubular cells: 203.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CACO-2: 544.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007700 Approved Mitochondria NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA007700: AB_2667900" "unprognostic (5.71e-2)" "unprognostic (4.04e-1)" "unprognostic (2.03e-2)" "unprognostic (2.07e-2)" "unprognostic (3.23e-1)" "unprognostic (5.99e-2)" "unprognostic (1.14e-1)" "unprognostic (1.11e-1)" "unprognostic (2.46e-1)" "unprognostic (1.24e-1)" "unprognostic (2.98e-1)" "unprognostic (1.62e-1)" "unprognostic (3.04e-3)" "unprognostic (1.57e-1)" "unprognostic (2.13e-1)" "unprognostic (8.40e-2)" "unprognostic (4.39e-2)" 50.0 130.2 52.5 35.4 53.6 45.9 48.0 53.7 55.8 40.2 53.7 53.0 45.5 43.1 44.1 76.0 39.6 30.1 142.1 54.3 56.1 101.6 188.4 36.4 34.4 53.8 54.7 41.1 79.0 66.0 44.3 31.1 52.4 47.5 56.9 30.1 52.7 44.6 273.1 58.2 42.1 53.0 51.5 43.8 63.0 58.4 56.5 50.2 43.3 210.3 50.6 49.8 43.4 51.9 99.4 169.9 65.5 101.1 95.3 95.0 77.6 102.0 107.2 213.2 149.0 544.8 56.7 174.5 94.7 134.0 111.2 127.2 153.1 111.0 162.0 138.9 136.4 63.4 97.0 115.0 152.0 141.5 75.7 106.0 160.4 148.4 124.9 96.1 118.9 123.8 140.8 101.3 130.0 126.8 163.6 73.9 74.8 166.2 75.9 116.8 139.4 172.8 113.0 89.2 88.6 84.3 181.2 357.6 101.8 102.7 189.6 97.6 102.5 94.4 71.2 110.1 179.4 89.0 115.0 125.6 134.4 93.8 95.7 41.6 48.5 42.6 33.5 47.1 33.5 49.0 35.3 43.8 60.1 31.1 37.5 37.1 19.4 33.8 35.0 40.3 42.5 52.6 52.5 53.6 53.7 55.8 54.3 56.1 53.8 54.7 52.4 51.5 56.5 51.9 20.4 9.6 18.1 13.1 27.7 27.5 32.5 61.6 33.0 24.5 43.1 35.2 96.7 62.9 31.5 47.8 4.2 82.0 17.0 55.9 189.8 102.0 44.9 15.5 22.3 29.1 23.4 54.3 12.7 143.2 97.0 29.5 34.7 20.5 11.4 46.8 22.9 125.1 69.6 28.6 13.1 42.4 32.6 36.5 25.7 132.4 30.7 25.6 58.7 5.6 51.9 39.6 36.0 9.0 8.9 112.7 37.6 33.1 46.1 46.7 74.5 203.6 13.5 18.4 13.1 22.0 47.0 64.3 45.0 55.2 30.1 81.3 22.5 66.1 66.3 38.8 POLR1G "A34.5, ASE-1, CAST, CD3EAP, PAF49, RPA34" ENSG00000117877 "RNA polymerase I subunit G" O15446 19 45406644-45410737 "Predicted intracellular proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 15.8;Extravillous trophoblasts: 26.3;Hofbauer cells: 11.5;Syncytiotrophoblasts: 7.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 14.5" "Lineage enriched" "Detected in all" 4 "dendritic cells: 14.5" "Cell line enhanced" "Detected in all" "U-251 MG: 200.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041664, HPA041734" Supported Enhanced "Nucleoplasm,Nucleoli fibrillar center,Mitochondria" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Nucleoli fibrillar center" Mitochondria "HPA041664: AB_10795693, HPA041734: AB_10794489" "unprognostic (1.03e-1)" "unprognostic (8.98e-2)" "unprognostic (9.28e-2)" "unprognostic (1.37e-3)" "unprognostic (2.46e-1)" "unprognostic (4.10e-3)" "prognostic unfavorable (4.79e-9)" "unprognostic (1.62e-3)" "unprognostic (3.21e-1)" "unprognostic (5.01e-2)" "unprognostic (2.99e-2)" "unprognostic (7.26e-2)" "unprognostic (6.29e-9)" "unprognostic (1.02e-1)" "unprognostic (2.81e-1)" "unprognostic (1.38e-2)" "unprognostic (4.53e-2)" 3.2 2.4 2.9 3.3 3.0 2.1 3.1 4.1 4.3 2.4 1.1 2.5 2.4 2.7 1.4 4.3 3.0 2.8 3.5 2.9 2.4 2.7 2.6 2.0 3.5 3.4 2.6 3.5 3.8 2.9 1.9 2.2 3.6 2.2 2.1 2.7 2.8 1.9 6.7 4.4 1.9 3.0 1.1 2.1 1.8 1.8 3.4 2.1 2.3 4.5 4.0 4.1 2.4 3.8 31.4 29.0 5.3 20.6 7.5 6.5 20.3 15.3 5.2 26.2 15.1 32.5 21.5 48.3 14.8 11.3 20.6 29.5 46.4 43.0 18.4 22.1 28.7 24.3 11.0 23.9 12.8 25.3 8.9 9.4 27.3 38.2 20.7 7.0 19.2 16.0 63.0 8.9 25.6 37.0 18.7 9.3 37.0 34.6 27.3 25.1 19.5 32.2 10.5 22.7 30.8 9.6 30.9 40.6 6.4 10.6 19.9 15.4 18.2 36.5 36.7 20.4 200.5 16.1 74.0 51.6 16.8 37.6 25.9 1.5 2.7 0.3 1.4 3.5 3.1 2.7 2.0 2.2 4.2 3.0 2.9 3.5 1.3 3.3 2.8 14.5 1.3 2.0 2.9 3.0 4.1 4.3 2.9 2.4 3.4 2.6 3.6 1.1 3.4 3.8 3.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 15.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 26.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 7.7 0.1 0.0 0.0 0.0 PPA2 FLJ20459 ENSG00000138777 "Inorganic pyrophosphatase 2" Q9H2U2 4 105369077-105474067 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030888, HPA031671, HPA031672" Supported Approved Mitochondria NA NA 150000 "Cluster 44: Non-specific - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA030888: AB_2673646, HPA031671: AB_10603986, HPA031672: AB_2673988" "prognostic unfavorable (2.98e-4)" "unprognostic (5.64e-2)" "prognostic favorable (6.60e-4)" "unprognostic (9.26e-3)" "unprognostic (2.93e-2)" "unprognostic (5.10e-2)" "unprognostic (1.15e-1)" "unprognostic (2.44e-1)" "unprognostic (1.50e-1)" "unprognostic (1.20e-1)" "unprognostic (7.05e-2)" "unprognostic (9.54e-2)" "prognostic favorable (1.27e-11)" "unprognostic (3.69e-1)" "unprognostic (1.94e-1)" "unprognostic (2.00e-1)" "unprognostic (1.10e-1)" 7.4 12.8 23.8 9.0 24.6 22.0 12.0 24.3 53.7 7.4 29.5 17.4 14.2 7.4 12.5 10.8 8.4 8.0 27.5 23.7 26.3 20.7 14.8 7.5 8.3 24.4 24.3 5.8 11.8 11.7 7.7 7.4 24.5 13.3 14.0 13.6 13.8 5.7 27.6 12.2 13.8 6.8 24.0 9.9 12.6 6.3 25.4 7.0 11.5 35.5 8.7 8.1 6.7 26.6 20.6 8.5 18.5 32.3 11.3 9.1 12.9 10.2 15.7 14.6 9.9 22.2 30.4 15.6 14.5 9.7 11.3 9.5 39.2 18.7 17.0 23.6 11.8 13.5 13.7 19.9 9.3 36.7 13.6 9.7 19.6 9.9 7.9 15.4 14.6 28.4 22.3 22.0 12.5 26.2 32.5 26.6 13.9 42.4 28.3 28.2 10.9 17.9 49.7 14.7 17.8 10.7 7.8 48.9 19.0 10.7 24.8 32.1 6.9 9.2 19.2 8.9 20.0 19.0 27.3 18.4 17.5 18.6 14.1 27.0 20.9 15.4 21.0 30.1 18.6 28.5 21.7 23.7 49.9 22.6 21.1 23.9 9.5 36.4 26.4 25.9 23.4 23.5 23.8 24.6 24.3 53.7 23.7 26.3 24.4 24.3 24.5 24.0 25.4 26.6 26.7 9.6 67.3 86.2 37.6 50.0 82.4 205.0 38.1 29.7 64.8 40.9 63.3 45.8 126.2 33.1 16.7 119.0 25.9 73.3 264.1 114.0 113.7 42.3 35.3 36.3 65.7 70.2 138.2 120.1 98.5 31.1 37.2 42.3 45.6 26.4 24.3 64.2 83.5 21.9 134.6 104.6 142.4 42.9 86.1 126.4 27.7 47.1 76.5 74.9 50.5 39.2 30.9 169.9 145.7 65.0 90.4 32.4 41.9 68.1 112.2 285.4 90.7 22.6 39.5 46.3 43.6 50.8 10.8 59.1 57.7 84.7 34.3 72.1 138.0 94.6 PPCS FLJ11838 ENSG00000127125 "Phosphopantothenoylcysteine synthetase" Q9HAB8 1 42456117-42473385 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 397.2;Proximal tubular cells: 316.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031361, HPA031363" Approved Approved Mitochondria NA NA 17000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA031361: AB_10602150, HPA031363: AB_2673844" "unprognostic (1.49e-1)" "unprognostic (6.71e-2)" "unprognostic (8.15e-2)" "unprognostic (1.55e-1)" "unprognostic (3.84e-3)" "unprognostic (1.68e-2)" "prognostic unfavorable (5.96e-5)" "unprognostic (2.71e-1)" "unprognostic (7.79e-3)" "unprognostic (9.13e-3)" "unprognostic (3.24e-2)" "unprognostic (2.44e-1)" "unprognostic (2.41e-2)" "unprognostic (6.45e-2)" "unprognostic (2.32e-1)" "unprognostic (2.80e-1)" "unprognostic (4.30e-2)" 51.0 62.7 28.2 34.6 29.3 27.1 65.0 29.8 34.6 44.2 36.8 63.5 58.0 35.8 71.0 48.4 31.7 43.1 42.5 28.6 32.0 88.1 99.6 39.8 43.5 30.1 28.8 30.2 66.9 59.8 27.8 38.0 29.1 52.3 58.0 22.4 59.3 44.2 45.9 47.0 56.4 29.0 31.6 42.2 64.7 15.0 29.9 27.8 64.8 40.4 38.2 43.3 40.1 32.9 83.4 34.3 17.2 28.8 52.3 55.0 72.1 40.7 43.3 49.1 44.2 30.7 93.3 22.6 80.7 46.2 30.3 48.8 11.5 62.5 40.3 66.2 35.1 39.9 34.7 31.3 72.5 39.9 69.4 48.8 98.9 35.8 62.4 58.2 48.3 29.9 16.9 17.0 50.5 47.3 20.4 40.1 22.6 70.0 49.8 22.6 18.8 45.3 106.2 70.7 23.0 25.0 47.9 113.2 129.4 50.2 56.7 167.8 31.1 28.2 41.1 42.9 46.5 58.6 37.3 17.5 12.6 44.4 61.0 298.8 231.5 325.6 114.5 245.4 135.2 171.5 141.1 128.0 195.9 182.4 149.5 132.9 159.5 185.6 237.2 135.8 160.9 262.8 28.2 29.3 29.8 34.6 28.6 32.0 30.1 28.8 29.1 31.6 29.9 32.9 61.0 57.7 84.1 5.9 62.6 23.3 42.3 99.4 42.7 12.1 91.3 100.2 104.3 84.4 90.8 64.4 6.2 172.2 52.6 129.2 397.2 96.5 3.5 66.7 43.9 48.7 31.3 29.0 7.4 136.8 131.0 52.9 61.7 59.3 57.0 52.8 44.6 120.1 107.4 11.8 7.0 124.9 103.7 84.4 44.3 4.6 60.6 76.3 81.8 6.5 127.0 64.8 79.3 8.0 8.7 98.5 125.2 63.6 41.8 51.7 159.7 316.3 63.2 28.0 26.3 26.2 48.9 10.3 20.8 66.3 36.2 134.6 62.5 103.2 101.2 60.1 PPFIBP2 Cclp1 ENSG00000166387 "PPFIA binding protein 2" Q8ND30 11 7513298-7657127 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 53.4;Extravillous trophoblasts: 56.2;Oligodendrocytes: 70.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 80.5;OE19: 100.4;RT4: 105.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001935, HPA003911" Enhanced Approved Mitochondria NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 21: OE19 - Mitochondria" "Cluster 44: Endometrium - Transcription" Mitochondria "HPA001935: AB_1079667, HPA003911: AB_1079666" "unprognostic (4.14e-2)" "unprognostic (7.04e-3)" "unprognostic (7.20e-3)" "unprognostic (5.79e-2)" "unprognostic (2.08e-1)" "prognostic favorable (2.32e-4)" "unprognostic (1.33e-1)" "prognostic favorable (2.26e-5)" "unprognostic (6.66e-3)" "unprognostic (2.90e-1)" "unprognostic (1.85e-1)" "unprognostic (1.17e-1)" "prognostic favorable (5.39e-8)" "unprognostic (1.78e-1)" "unprognostic (3.38e-1)" "unprognostic (2.52e-2)" "prognostic favorable (1.34e-5)" 10.8 11.7 21.5 12.0 34.2 7.6 16.6 24.9 24.4 14.7 51.3 22.4 26.4 6.7 33.5 27.3 17.2 15.7 13.0 21.8 26.2 19.0 35.4 11.6 15.2 27.4 29.8 14.3 9.4 66.5 4.8 21.0 29.0 18.2 26.5 2.8 54.8 32.8 33.4 33.2 26.0 5.4 20.6 11.1 44.1 31.5 31.7 4.5 37.5 21.4 25.0 29.5 21.8 43.8 2.0 32.7 5.3 3.1 6.1 0.4 80.5 7.1 16.1 4.1 4.0 26.7 4.6 9.7 3.7 4.1 15.1 14.2 21.0 2.1 3.7 3.9 2.4 0.0 0.3 17.1 8.4 19.6 9.3 10.7 7.6 0.0 4.5 0.4 1.5 2.0 0.9 26.5 4.0 15.9 0.0 19.0 37.8 100.4 0.1 3.3 0.1 17.4 0.1 105.0 1.5 12.4 1.1 28.9 21.9 14.6 4.0 14.7 0.5 1.9 2.8 6.4 0.7 14.1 11.1 8.3 2.3 4.5 13.0 3.4 9.1 6.5 3.1 11.2 2.3 12.7 5.0 2.1 8.3 7.2 6.6 5.2 4.2 2.6 14.4 0.6 1.1 5.2 21.5 34.2 24.9 24.4 21.8 26.2 27.4 29.8 29.0 20.6 31.7 43.8 1.7 16.0 13.6 3.9 21.2 5.5 18.7 4.5 10.2 1.5 10.1 7.7 5.2 11.5 13.7 14.7 18.8 9.1 1.6 29.8 9.8 5.8 53.4 6.7 4.8 3.2 3.6 0.0 3.8 9.6 56.2 7.7 40.2 35.7 7.0 0.6 1.1 17.3 7.1 0.0 6.0 23.2 8.2 10.4 7.2 47.2 4.7 11.3 16.0 17.8 15.7 1.7 3.1 49.8 70.5 6.9 22.8 7.2 9.0 13.4 26.8 19.7 7.5 3.3 0.0 5.7 10.2 22.2 2.6 10.7 9.9 4.8 2.0 1.2 18.0 18.6 PPOX "PPO, VP" ENSG00000143224 "Protoporphyrinogen oxidase" P50336 1 161166056-161178013 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Heme biosynthesis, Porphyrin biosynthesis" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 65.9;Respiratory ciliated cells: 84.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030123 Uncertain Approved Vesicles,Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" Mitochondria "Vesicles, Cytosol" "HPA030123: AB_10603987" "unprognostic (1.17e-1)" "unprognostic (4.73e-2)" "unprognostic (9.88e-2)" "unprognostic (2.13e-2)" "unprognostic (3.24e-1)" "unprognostic (1.64e-2)" "unprognostic (9.58e-3)" "unprognostic (1.79e-2)" "unprognostic (9.17e-2)" "unprognostic (1.17e-1)" "unprognostic (2.18e-3)" "unprognostic (7.12e-3)" "prognostic unfavorable (9.89e-4)" "unprognostic (6.12e-2)" "unprognostic (2.23e-1)" "unprognostic (3.27e-1)" "unprognostic (1.80e-2)" 9.3 17.1 24.2 3.5 24.5 25.2 10.3 25.2 38.2 14.5 24.7 12.7 3.9 10.9 8.3 8.9 22.0 4.7 13.1 24.4 24.7 15.5 11.5 8.6 5.7 25.0 25.0 13.8 10.8 7.2 13.7 6.5 24.6 13.4 3.9 12.6 8.7 7.7 7.6 11.2 8.5 6.6 25.0 13.6 10.9 6.9 24.0 5.0 11.9 5.6 5.2 11.6 9.6 25.4 10.0 8.0 12.7 8.5 10.4 9.3 3.5 5.9 5.7 7.5 10.3 10.4 9.3 7.4 14.3 5.3 4.1 6.3 9.8 8.8 7.1 4.6 20.3 9.0 18.9 23.9 8.6 3.0 4.6 7.6 11.0 6.3 9.4 9.4 14.7 7.0 22.8 11.2 5.6 9.2 12.0 8.6 8.2 11.2 18.8 13.6 8.2 16.7 15.1 4.2 9.8 14.7 6.6 10.3 12.0 14.6 19.9 9.5 5.7 6.5 7.1 6.5 7.5 19.4 15.3 10.5 6.8 6.0 4.9 6.3 7.2 5.3 10.4 7.6 7.2 9.0 7.8 7.6 10.4 8.2 6.8 6.9 2.9 12.0 5.2 6.6 16.1 7.8 24.2 24.5 25.2 38.2 24.4 24.7 25.0 25.0 24.6 25.0 24.0 25.4 10.9 3.2 13.7 10.4 9.8 12.0 8.3 16.6 9.1 18.0 12.1 14.1 10.1 4.3 15.6 7.3 22.9 21.4 10.6 3.6 21.5 9.5 9.8 39.1 5.9 8.3 6.0 65.9 5.9 5.6 9.4 9.1 5.1 4.6 6.3 12.3 8.9 6.1 9.3 15.2 7.5 7.3 26.4 4.7 8.4 12.1 10.2 8.0 1.8 5.6 8.1 10.4 8.2 9.0 8.9 6.3 3.8 6.8 16.9 3.2 6.6 17.2 84.4 20.9 6.6 9.6 15.6 12.8 9.3 7.2 14.9 10.4 10.6 11.1 7.5 6.2 PPP1R3D PPP1R6 ENSG00000132825 "Protein phosphatase 1 regulatory subunit 3D" O95685 20 59936663-59940305 "Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.0" "Group enriched" "Detected in many" 4 "granulocytes: 3.0;monocytes: 1.8" "Cell line enhanced" "Detected in many" "SK-BR-3: 24.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041146 Approved Approved Nucleoli,Vesicles,Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 28: BEWO - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Vesicles, Mitochondria" Nucleoli "HPA041146: AB_10793870" "unprognostic (2.50e-3)" "unprognostic (3.55e-3)" "unprognostic (6.90e-2)" "unprognostic (1.23e-1)" "unprognostic (7.23e-2)" "unprognostic (5.87e-2)" "unprognostic (5.73e-2)" "unprognostic (2.39e-3)" "unprognostic (5.54e-2)" "unprognostic (3.27e-1)" "unprognostic (3.52e-2)" "unprognostic (1.20e-1)" "unprognostic (1.48e-2)" "prognostic favorable (9.14e-4)" "unprognostic (4.71e-2)" "unprognostic (1.47e-2)" "unprognostic (5.71e-2)" 3.7 2.9 6.7 4.8 7.3 6.3 3.8 7.3 7.4 4.2 4.6 3.7 5.3 3.7 3.4 5.8 3.5 3.0 5.5 5.9 6.6 4.1 1.1 3.5 3.9 7.6 6.9 4.5 3.5 5.1 2.8 5.4 7.1 6.3 3.0 2.1 4.3 5.6 7.1 4.2 5.0 3.8 7.0 4.9 5.4 1.9 6.8 3.3 3.6 9.8 5.1 3.4 3.6 6.7 5.1 3.1 2.1 4.3 4.6 4.8 17.3 6.6 7.1 7.9 3.8 4.9 6.8 2.1 8.0 5.5 4.9 14.7 4.3 4.7 5.1 5.0 3.4 5.6 4.2 2.6 4.2 2.3 15.2 3.4 12.7 2.8 2.4 4.2 4.4 1.4 1.0 0.5 5.1 7.9 1.9 7.5 1.5 9.6 7.3 2.4 0.9 3.3 5.3 8.1 4.0 2.4 8.2 24.6 7.4 3.9 9.0 8.2 4.7 4.6 1.9 4.9 1.1 1.7 4.5 0.5 3.5 8.1 2.9 0.3 0.7 3.0 0.4 0.3 0.3 0.3 0.3 0.3 0.5 0.2 0.3 0.2 1.8 0.4 1.8 0.2 0.4 0.2 6.7 7.3 7.3 7.4 5.9 6.6 7.6 6.9 7.1 7.0 6.8 6.7 10.4 9.6 0.5 12.4 3.3 1.3 4.6 2.6 4.6 7.8 5.7 4.2 6.7 7.2 4.3 5.5 2.1 14.3 4.5 4.0 5.9 1.9 0.4 3.0 4.9 8.6 1.8 1.3 0.9 3.1 6.4 3.3 3.1 3.4 5.7 3.9 9.7 0.4 5.2 13.5 2.4 3.6 0.0 9.8 2.6 1.3 3.1 7.4 5.4 1.0 8.7 11.0 13.4 2.5 1.8 3.5 6.1 4.5 3.7 6.7 6.7 6.2 4.3 11.4 6.6 5.7 4.9 0.4 3.6 4.7 3.1 4.9 5.6 5.1 3.8 9.5 PPP1R3E FLJ00089 ENSG00000235194 "Protein phosphatase 1 regulatory subunit 3E" Q9H7J1 14 23295652-23302859 "Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 47.0" "Cell type enhanced" "Detected in all" "Early spermatids: 111.9;Late spermatids: 62.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/70: 41.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA061600 Approved Approved "Microtubules,Mitotic spindle,Mitochondria" Yes No "Cluster 51: Monocytes - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 29: U-266 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" "Microtubules, Mitochondria" "Mitotic spindle" "HPA061600: AB_2684566" "unprognostic (3.45e-2)" "unprognostic (1.57e-2)" "prognostic unfavorable (6.89e-5)" "unprognostic (4.05e-1)" "unprognostic (2.85e-2)" "unprognostic (1.29e-2)" "unprognostic (7.12e-2)" "prognostic favorable (3.10e-4)" "unprognostic (1.73e-2)" "unprognostic (1.18e-1)" "unprognostic (1.77e-3)" "unprognostic (2.41e-1)" "unprognostic (8.67e-3)" "unprognostic (8.46e-2)" "unprognostic (2.88e-1)" "unprognostic (8.12e-2)" "unprognostic (5.46e-2)" 5.8 8.0 15.2 5.7 17.9 3.9 6.4 17.9 23.8 10.2 9.7 7.4 6.3 6.4 10.1 6.0 9.5 3.3 6.2 15.0 15.3 11.6 11.2 5.7 9.5 18.5 16.5 12.5 10.6 5.7 19.3 2.7 19.4 12.1 5.9 47.0 8.5 6.2 14.9 10.9 13.3 3.4 13.8 15.1 9.0 14.7 17.7 8.2 14.9 5.4 8.2 7.9 8.5 23.3 1.1 3.0 3.6 2.5 6.9 2.9 1.7 1.2 2.2 2.0 1.7 1.7 5.8 11.2 0.8 1.6 2.2 7.6 2.1 1.2 2.5 4.0 2.1 2.0 6.9 4.0 1.8 2.3 4.4 2.5 4.5 1.2 6.1 3.3 0.9 6.0 1.9 9.8 1.7 2.6 2.1 3.6 0.9 3.6 2.8 3.4 2.5 7.2 1.1 2.5 4.5 1.2 1.8 1.6 1.2 1.8 1.9 0.8 1.7 2.4 1.3 4.1 0.9 41.1 4.6 5.1 1.9 4.0 1.5 0.2 0.4 0.2 0.5 1.4 0.6 1.0 0.1 0.2 0.3 0.6 0.5 0.3 0.4 0.2 1.8 0.3 0.4 0.3 15.2 17.9 17.9 23.8 15.0 15.3 18.5 16.5 19.4 13.8 17.7 23.3 5.8 3.2 4.8 30.0 25.4 5.6 9.0 5.3 11.4 59.4 7.8 11.6 8.8 7.2 5.0 20.2 37.5 8.2 12.8 8.0 5.9 2.1 111.9 3.7 6.6 7.2 8.4 7.2 25.0 3.3 2.0 6.1 20.4 4.3 3.8 9.4 7.5 7.2 7.4 32.0 33.0 7.7 4.1 9.5 9.6 62.9 27.4 9.2 10.6 15.9 8.1 20.4 26.8 16.1 56.1 2.4 11.6 25.9 11.9 6.7 19.5 9.5 4.8 38.1 13.1 3.5 5.4 36.5 13.9 8.4 9.1 5.2 15.7 7.2 9.6 8.6 PPP3CB "CALNA2, CALNB, CNA2, PP2Bbeta" ENSG00000107758 "Protein phosphatase 3 catalytic subunit beta" P16298 10 73436433-73496024 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "skeletal muscle: 379.3;tongue: 179.7" "Cell type enhanced" "Detected in all" "Excitatory neurons: 119.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008233, HPA008823" Uncertain Approved Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA008233: AB_1855661, HPA008823: AB_2668148" "unprognostic (3.05e-1)" "unprognostic (2.54e-1)" "unprognostic (1.50e-1)" "unprognostic (4.93e-2)" "unprognostic (8.93e-2)" "unprognostic (4.28e-2)" "prognostic unfavorable (9.59e-4)" "unprognostic (1.14e-1)" "unprognostic (1.34e-1)" "unprognostic (2.12e-2)" "prognostic favorable (6.96e-5)" "unprognostic (4.73e-2)" "unprognostic (1.51e-1)" "unprognostic (1.01e-1)" "unprognostic (1.45e-1)" "unprognostic (2.66e-1)" "unprognostic (1.68e-2)" 44.8 37.5 40.5 29.8 51.1 19.8 32.1 49.5 63.1 30.3 26.7 41.4 24.2 40.3 34.5 33.1 30.9 28.3 41.3 56.9 29.5 28.1 21.8 23.5 34.9 25.4 25.2 39.6 25.3 39.2 30.6 25.5 28.7 39.1 29.6 57.0 26.6 39.8 379.3 26.3 22.6 48.2 27.2 25.3 24.3 29.0 29.1 32.9 23.5 179.7 36.1 34.3 24.3 44.9 53.7 29.0 50.9 53.0 71.4 98.3 24.5 48.0 65.7 46.1 45.4 18.6 26.8 47.1 15.3 70.0 21.8 28.1 41.6 36.9 64.5 66.6 34.0 20.3 25.0 35.5 42.7 45.2 40.2 70.1 43.5 43.6 58.1 84.7 32.3 40.6 25.6 54.0 94.1 16.9 40.7 41.6 20.7 23.3 83.8 26.9 27.7 22.4 45.1 25.6 27.2 31.5 28.1 69.5 36.4 42.1 52.4 43.2 35.6 36.6 33.7 29.5 66.1 35.8 105.3 33.0 45.3 64.0 21.3 2.2 2.0 3.5 4.0 2.7 4.8 2.7 4.3 4.4 2.1 2.3 3.4 5.1 1.1 3.5 1.7 4.0 7.8 1.9 40.5 51.1 49.5 63.1 56.9 29.5 25.4 25.2 28.7 27.2 29.1 44.9 23.0 3.2 14.3 72.5 31.6 25.6 29.8 13.2 27.3 54.8 25.7 16.9 48.9 14.3 12.8 18.4 20.9 21.0 23.7 11.1 62.6 18.1 11.8 20.0 24.2 21.5 42.6 30.7 119.5 19.4 16.8 32.6 20.4 18.8 21.0 35.4 18.9 14.2 20.3 38.7 111.0 13.2 18.3 31.7 24.2 9.9 33.5 25.2 26.6 51.5 29.6 34.8 18.6 79.4 54.4 16.7 12.9 29.0 34.1 27.1 13.4 34.2 17.6 30.1 6.6 41.8 36.4 43.8 49.2 32.1 31.5 22.2 27.3 28.4 13.1 22.1 PRDX1 "NKEFA, PAGA" ENSG00000117450 "Peroxiredoxin 1" Q06830 1 45510914-45542732 "Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Antioxidant, Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 2690.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004682, HPA007730" Approved Approved Mitochondria NA NA 110000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 27: Brain & Skin - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria "CAB004682: AB_437046, HPA007730: AB_1855204" "unprognostic (1.28e-2)" "unprognostic (4.64e-1)" "unprognostic (2.22e-2)" "unprognostic (3.65e-1)" "unprognostic (2.38e-1)" "unprognostic (3.95e-2)" "prognostic unfavorable (1.17e-5)" "unprognostic (2.47e-1)" "unprognostic (1.31e-1)" "unprognostic (4.68e-2)" "unprognostic (3.05e-2)" "unprognostic (2.90e-1)" "unprognostic (2.39e-2)" "unprognostic (5.99e-2)" "unprognostic (2.88e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (2.89e-4)" 277.8 362.9 642.4 290.2 667.1 86.7 454.3 700.7 747.3 314.1 627.0 326.7 501.4 255.3 459.4 945.8 306.3 297.4 542.9 613.0 700.8 785.5 841.2 340.2 371.4 712.1 706.3 255.5 122.7 214.6 210.0 353.3 711.6 256.0 327.1 347.3 348.6 307.2 571.4 296.5 402.1 329.3 713.5 265.8 355.5 143.7 671.4 262.8 802.3 477.7 603.3 393.2 375.3 766.6 1028.1 1743.7 735.2 942.9 828.4 701.9 1459.3 1134.8 1144.1 1183.0 964.3 932.3 429.2 899.1 1125.9 1237.6 1448.6 967.6 1640.2 1101.3 1193.0 696.9 1266.4 678.6 2042.8 2484.7 361.0 793.6 848.9 610.4 813.6 1201.7 283.8 657.7 1409.7 1044.0 1271.8 292.7 1225.2 829.4 1053.7 772.5 2339.8 2241.0 1867.3 1863.6 934.0 1177.7 2211.5 872.4 987.5 495.1 1035.3 2524.2 73.3 2157.3 760.6 631.1 1208.1 474.8 1071.9 1034.4 1541.5 206.1 1220.5 1678.2 791.4 537.9 278.7 469.3 325.6 111.6 155.7 367.1 205.4 253.8 246.8 209.3 293.9 221.6 150.3 166.6 12.1 123.8 407.5 195.9 438.2 416.3 642.4 667.1 700.7 747.3 613.0 700.8 712.1 706.3 711.6 713.5 671.4 766.6 530.7 522.4 259.0 48.3 330.1 607.3 1115.3 1161.1 745.0 161.3 387.0 510.9 54.9 397.5 685.2 617.9 104.3 1258.6 151.5 339.3 946.9 1015.7 19.7 662.7 281.2 437.8 174.5 304.2 15.5 442.8 1773.2 462.0 500.0 435.5 325.3 463.2 326.3 875.2 1467.4 206.9 17.1 295.0 545.3 366.9 980.7 44.2 498.6 534.8 581.7 12.2 545.7 416.4 62.8 24.1 90.5 804.4 384.9 410.7 612.8 1100.9 995.0 2690.9 919.1 402.2 309.0 279.0 982.6 84.5 329.2 1346.9 528.6 1114.9 270.9 499.4 398.8 1462.7 PRODH "HSPOX2, PIG6, PRODH1, PRODH2, TP53I6" ENSG00000100033 "Proline dehydrogenase 1" O43272 22 18912777-18936553 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Proline metabolism" Oxidoreductase "Disease variant, Schizophrenia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 49.2;skin 1: 39.8" "Cell type enriched" "Detected in some" 7 "Astrocytes: 183.1" "Cancer enhanced" "Detected in many" "testis cancer: 11.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "OE19: 91.3;RPTEC TERT1: 35.9" HPA020361 Approved Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 59: Non-specific - Translation" "Cluster 21: OE19 - Mitochondria" "Cluster 64: Astrocytes - Nervous system maintenance" Mitochondria "Nucleoplasm, Vesicles" "HPA020361: AB_10963116" "unprognostic (2.46e-2)" "prognostic favorable (1.54e-4)" "unprognostic (1.40e-1)" "unprognostic (3.70e-2)" "unprognostic (3.80e-2)" "unprognostic (1.20e-1)" "unprognostic (1.78e-2)" "unprognostic (1.07e-2)" "unprognostic (2.49e-2)" "unprognostic (6.56e-2)" "unprognostic (3.12e-2)" "unprognostic (1.61e-2)" "unprognostic (7.44e-2)" "unprognostic (1.07e-1)" "unprognostic (1.21e-1)" "unprognostic (5.34e-2)" "unprognostic (3.94e-2)" 7.9 0.7 5.8 0.4 6.4 0.0 8.5 3.1 9.0 5.0 34.0 3.1 5.6 1.5 0.1 11.6 5.8 0.1 18.6 6.5 2.8 16.7 15.6 20.6 0.2 7.3 4.7 0.5 1.4 0.0 5.4 0.2 2.5 3.2 0.3 0.6 4.2 0.2 49.2 39.8 32.5 0.0 3.3 0.5 3.5 1.7 7.6 0.3 7.4 6.2 0.8 4.2 8.5 3.4 0.0 0.8 0.0 0.3 0.9 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.3 0.0 0.0 2.9 3.9 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 2.9 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.6 4.5 91.3 0.0 0.0 0.0 0.4 35.9 0.9 0.1 0.2 0.8 1.4 0.3 5.2 1.4 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.8 6.4 3.1 9.0 6.5 2.8 7.3 4.7 2.5 3.3 7.6 3.4 0.1 16.0 25.6 183.1 0.0 5.1 0.3 13.1 0.0 0.0 0.2 0.1 1.8 0.0 11.5 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.6 1.2 0.2 0.4 3.5 0.0 0.5 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 1.1 0.0 2.0 0.0 1.5 0.1 0.0 0.1 21.4 17.8 0.0 0.6 0.0 14.1 2.1 0.0 2.3 0.0 0.0 0.0 8.0 0.1 21.0 0.1 0.0 1.1 0.6 0.2 0.4 1.0 15.2 0.0 0.3 0.0 1.6 0.2 PRR19 MGC70924 ENSG00000188368 "Proline rich 19" A6NJB7 19 42302098-42310814 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 21.6" "Group enriched" "Detected in some" 9 "Early spermatids: 26.7;Late spermatids: 60.1;Spermatocytes: 37.9;Spermatogonia: 22.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA070350 Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Nuclear bodies,Mitotic chromosome,Mitochondria" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nucleoli, Nucleoli rim, Mitotic chromosome" "Nucleoplasm, Nuclear bodies, Mitochondria" "HPA070350: AB_2686259" "unprognostic (2.05e-1)" "unprognostic (8.03e-3)" "unprognostic (4.02e-2)" "unprognostic (7.55e-3)" "unprognostic (7.33e-2)" "unprognostic (1.08e-2)" "unprognostic (2.44e-5)" "unprognostic (3.57e-1)" "unprognostic (1.92e-2)" "unprognostic (8.10e-3)" "unprognostic (3.85e-2)" "unprognostic (2.77e-1)" "unprognostic (2.87e-3)" "unprognostic (4.21e-1)" "unprognostic (7.26e-2)" "unprognostic (1.78e-1)" "unprognostic (4.36e-2)" 0.4 1.1 1.9 0.7 2.5 2.3 0.5 2.1 2.4 0.7 1.3 0.4 0.4 0.6 0.4 1.1 0.5 0.5 0.2 1.9 1.7 0.7 0.6 0.3 0.5 1.8 1.5 0.5 0.4 0.4 0.9 0.4 1.9 0.7 0.2 0.5 0.7 0.4 0.3 0.7 0.5 0.3 1.4 0.5 0.4 21.6 2.0 0.6 0.4 0.1 0.5 0.4 0.7 2.0 2.7 3.9 2.2 2.9 0.1 0.2 2.2 1.2 1.2 3.5 3.5 1.6 2.5 0.5 4.5 1.3 2.6 0.8 1.0 1.0 0.7 1.8 1.0 2.8 2.0 1.0 0.8 0.7 1.6 1.1 1.6 2.3 0.4 0.7 0.6 2.9 1.5 1.3 1.6 6.2 2.7 1.3 2.3 2.5 0.0 1.0 0.4 0.2 1.1 2.1 4.9 1.9 2.1 1.5 0.6 0.6 2.0 1.0 0.8 2.3 3.4 0.5 2.1 0.2 1.0 0.8 2.4 2.0 2.4 0.4 0.4 0.1 0.4 0.4 0.1 0.6 0.3 0.5 0.5 0.4 0.4 0.2 0.4 0.5 0.1 0.3 0.5 0.2 1.9 2.5 2.1 2.4 1.9 1.7 1.8 1.5 1.9 1.4 2.0 2.0 1.2 0.0 0.5 0.0 0.7 0.6 0.9 1.9 4.0 0.4 2.7 2.8 0.5 0.0 0.6 0.0 0.0 0.9 0.3 0.8 1.9 0.9 26.7 1.0 0.7 1.2 0.0 0.0 0.4 1.2 0.6 0.6 1.1 1.5 0.0 0.3 0.0 0.4 0.8 1.7 0.4 0.1 0.0 0.0 0.3 60.1 1.2 0.4 0.0 1.0 0.1 0.0 1.0 1.0 0.3 0.4 1.2 1.2 0.6 0.4 0.6 0.6 2.3 0.2 0.0 0.8 0.7 37.9 22.5 2.1 0.9 0.5 0.4 0.6 0.4 0.7 PSMG4 "C6orf86, PAC4" ENSG00000180822 "Proteasome assembly chaperone 4" Q5JS54 6 3231403-3303373 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067652, HPA074376, HPA075846" Approved Approved Nucleoplasm,Mitochondria No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 25: RPMI-8226 - Immune response" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Mitochondria" "HPA067652: AB_2685880, HPA074376: , HPA075846: " "unprognostic (3.13e-3)" "unprognostic (6.00e-2)" "unprognostic (3.60e-1)" "unprognostic (4.11e-2)" "unprognostic (4.11e-1)" "unprognostic (2.20e-1)" "unprognostic (6.52e-3)" "unprognostic (1.57e-2)" "unprognostic (6.96e-2)" "unprognostic (6.74e-3)" "unprognostic (7.40e-3)" "unprognostic (3.02e-2)" "prognostic unfavorable (7.45e-4)" "unprognostic (1.59e-1)" "unprognostic (8.18e-2)" "unprognostic (2.54e-1)" "unprognostic (3.48e-2)" 20.3 18.3 12.8 8.2 15.7 13.8 20.0 19.8 13.7 16.9 5.0 24.1 14.1 18.9 18.6 19.9 18.4 6.9 15.1 11.5 14.6 20.1 26.9 13.7 10.2 17.6 16.0 16.6 33.4 12.0 22.2 7.0 18.1 19.3 6.9 9.9 20.2 13.4 37.1 20.8 16.8 9.5 13.5 14.4 21.4 16.2 15.9 9.3 21.1 11.1 7.7 19.8 16.8 23.8 61.8 29.0 17.5 42.8 15.3 23.1 29.5 27.2 20.0 25.9 41.4 25.1 20.6 21.0 73.1 16.4 20.2 28.9 15.0 18.9 16.9 34.7 65.2 16.9 33.4 66.6 19.2 48.7 16.9 19.8 20.1 18.8 27.8 14.8 32.4 39.9 65.0 15.1 14.0 58.2 27.6 88.9 21.4 31.3 57.7 36.5 9.5 116.2 21.1 24.0 74.3 21.3 12.9 16.7 61.4 16.5 22.0 21.0 31.7 21.4 20.4 24.6 26.6 48.7 76.4 39.4 15.2 34.1 29.3 16.2 35.5 24.4 25.3 36.9 29.4 50.2 42.1 30.8 28.4 52.1 40.9 35.7 8.9 32.3 36.3 33.9 39.4 23.9 12.8 15.7 19.8 13.7 11.5 14.6 17.6 16.0 18.1 13.5 15.9 23.8 45.2 22.4 21.2 18.6 25.3 27.9 29.1 44.2 38.7 32.0 53.1 88.4 21.9 37.1 26.9 44.1 8.4 39.3 15.2 23.6 84.1 43.9 31.4 23.6 25.9 35.2 22.8 18.5 9.6 87.5 37.8 30.4 15.8 17.1 22.2 38.8 28.2 64.5 35.1 25.2 17.8 31.1 28.5 19.2 21.1 13.3 37.0 18.4 30.2 5.6 35.7 22.0 32.0 21.6 15.7 57.8 25.8 23.0 18.9 47.0 47.3 67.2 22.6 29.4 46.0 45.5 54.0 29.6 78.2 39.6 38.2 12.0 23.7 30.0 35.4 27.1 PSTPIP2 ENSG00000152229 "Proline-serine-threonine phosphatase interacting protein 2" Q9H939 18 45983536-46072272 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 72.4;lymphoid tissue: 63.4;skeletal muscle: 33.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 44.6;Erythroid cells: 46.7;Macrophages: 58.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 112.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 102.0;HMC-1: 108.3" "Low region specificity" "Detected in all" "HPA040923, HPA040944" Enhanced Approved "Nucleoplasm,Plasma membrane,Mitochondria" No No 1500000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane, Mitochondria" Nucleoplasm "HPA040923: AB_10794429, HPA040944: AB_10795485" "unprognostic (1.61e-1)" "unprognostic (9.08e-2)" "unprognostic (1.21e-1)" "unprognostic (1.53e-2)" "unprognostic (2.57e-2)" "unprognostic (1.60e-1)" "unprognostic (1.17e-2)" "unprognostic (4.80e-3)" "unprognostic (1.87e-1)" "unprognostic (1.33e-1)" "unprognostic (5.83e-2)" "unprognostic (3.06e-1)" "prognostic unfavorable (2.39e-7)" "unprognostic (5.21e-2)" "unprognostic (3.55e-1)" "unprognostic (1.61e-1)" "unprognostic (1.93e-1)" 4.4 4.6 0.9 11.1 0.9 72.4 8.5 0.8 1.5 4.2 1.8 4.4 3.6 2.9 1.4 5.1 4.0 5.3 2.1 0.8 1.1 3.7 10.0 11.4 6.3 1.8 1.2 3.6 3.5 3.8 2.9 12.1 1.5 8.0 5.1 2.8 5.9 2.7 33.0 8.8 4.5 4.6 1.1 63.4 6.4 1.3 1.2 3.9 2.1 5.8 4.9 9.6 4.3 1.4 2.9 0.0 3.8 0.1 0.9 6.7 20.6 15.0 7.4 5.3 4.5 11.6 4.0 0.1 0.9 5.0 0.0 36.2 20.3 28.1 6.6 0.0 3.2 102.0 4.6 0.2 5.9 6.0 108.3 5.0 34.4 5.0 16.3 4.8 10.6 0.2 24.8 0.1 23.1 3.6 0.9 0.1 2.3 0.0 0.1 0.1 7.5 4.9 11.2 37.0 0.3 2.1 2.4 10.3 0.5 28.2 32.6 12.0 7.6 0.6 8.2 0.8 0.2 0.1 0.3 0.1 1.3 0.2 0.4 77.3 25.3 112.8 10.4 35.0 3.6 0.1 6.2 7.7 25.3 0.1 7.2 8.8 13.5 2.9 36.4 0.9 4.1 20.0 0.9 0.9 0.8 1.5 0.8 1.1 1.8 1.2 1.5 1.1 1.2 1.4 1.7 12.8 11.6 0.7 2.4 13.8 19.4 44.6 15.4 0.7 11.1 17.1 3.5 2.8 24.9 0.0 0.0 26.6 21.8 0.6 3.9 9.6 2.0 4.1 2.6 3.1 1.2 46.7 1.6 3.9 3.3 4.2 11.2 11.2 43.6 20.6 7.1 17.3 14.6 0.0 1.4 4.2 6.1 42.5 5.5 7.3 2.8 58.7 7.2 2.8 37.4 10.9 25.7 2.0 0.9 17.7 0.3 2.2 3.6 39.7 0.5 4.1 13.0 0.4 6.6 3.1 7.7 1.1 1.6 7.3 10.2 8.8 17.8 7.1 2.4 21.8 PTCD1 KIAA0632 ENSG00000106246 "Pentatricopeptide repeat domain 1" O75127 7 99416739-99466163 "Predicted intracellular proteins" "tRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CACO-2: 29.2" "HPA020106, HPA047679" Uncertain Approved Mitochondria NA NA "Cluster 32: T-cells - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "HPA020106: AB_2176551, HPA047679: AB_2680119" "unprognostic (4.70e-2)" "unprognostic (3.38e-2)" "unprognostic (4.19e-2)" "unprognostic (6.05e-2)" "unprognostic (1.17e-1)" "unprognostic (2.11e-2)" "prognostic unfavorable (2.34e-4)" "unprognostic (4.39e-2)" "unprognostic (2.00e-1)" "unprognostic (4.09e-2)" "unprognostic (1.14e-2)" "unprognostic (8.87e-2)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.49e-1)" "unprognostic (1.50e-1)" "unprognostic (7.71e-2)" "unprognostic (7.10e-3)" 3.4 3.6 3.5 2.6 3.5 5.6 3.4 4.2 4.0 3.3 2.8 3.8 2.7 3.7 0.8 4.4 3.8 2.7 4.1 3.2 3.1 3.2 4.7 2.8 3.4 4.1 3.6 3.4 3.6 1.6 2.9 1.8 3.6 4.2 1.3 1.7 3.4 2.1 6.7 4.3 4.0 1.0 3.1 4.9 3.9 4.3 3.6 1.3 3.2 2.6 1.5 3.6 3.4 4.2 4.8 9.8 3.3 9.3 3.1 2.5 9.2 6.6 2.4 4.6 3.3 29.2 5.7 9.6 7.4 1.8 7.7 5.1 4.0 5.9 1.6 7.7 11.2 4.9 8.1 7.2 4.8 5.1 9.0 2.0 3.7 3.8 3.8 3.1 1.4 6.0 10.0 6.4 2.3 13.8 9.0 12.9 6.1 4.8 8.0 5.4 4.3 11.9 2.5 5.1 6.1 6.5 7.4 24.2 6.3 4.7 5.2 5.3 2.7 6.9 8.1 13.7 7.1 9.5 9.1 10.2 7.1 6.7 9.7 1.8 2.0 0.9 3.3 2.3 2.2 1.8 2.1 2.2 1.4 2.5 2.4 3.0 1.9 2.0 1.7 2.1 1.5 1.5 3.5 3.5 4.2 4.0 3.2 3.1 4.1 3.6 3.6 3.1 3.6 4.2 3.5 0.0 5.8 0.0 6.6 6.2 4.0 5.2 4.6 7.9 4.9 4.7 5.8 4.3 4.0 5.5 10.4 9.9 4.1 4.2 1.9 5.3 2.1 4.7 8.6 5.3 7.3 2.5 0.0 6.7 5.6 4.2 3.6 5.2 12.7 12.9 4.6 6.1 6.6 8.4 0.0 6.2 6.1 3.2 6.1 1.8 3.7 3.7 3.6 0.0 3.8 5.6 1.0 0.0 0.0 5.0 2.5 3.0 4.1 3.6 4.5 3.2 5.8 9.3 0.0 8.6 6.7 8.7 7.6 5.1 4.1 5.6 5.7 6.2 6.3 2.6 PTGES2 "C9orf15, FLJ14038" ENSG00000148334 "Prostaglandin E synthase 2" Q9H7Z7 9 128120693-128128462 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Cardiomyocytes: 700.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020631, HPA020733" Approved Approved Mitochondria No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA020631: AB_1855887, HPA020733: AB_2670508" "unprognostic (1.23e-1)" "unprognostic (1.86e-2)" "unprognostic (1.60e-1)" "unprognostic (1.95e-2)" "unprognostic (1.55e-1)" "unprognostic (1.68e-2)" "unprognostic (5.13e-3)" "unprognostic (2.56e-1)" "unprognostic (1.57e-1)" "unprognostic (7.10e-2)" "unprognostic (2.81e-2)" "unprognostic (4.33e-2)" "prognostic favorable (5.83e-7)" "unprognostic (2.10e-2)" "unprognostic (1.46e-1)" "unprognostic (1.10e-1)" "unprognostic (1.05e-1)" 18.1 49.8 31.6 15.6 33.9 6.5 16.0 29.1 45.8 18.1 32.4 30.6 27.5 21.6 4.0 35.3 17.6 11.4 95.0 35.6 33.0 36.4 37.7 14.8 17.6 31.5 31.5 16.1 37.6 35.2 41.4 9.7 32.1 24.6 9.2 10.0 26.1 16.8 117.9 20.9 23.8 7.5 27.3 21.1 29.6 14.5 31.5 11.9 23.5 78.7 9.7 22.3 22.0 31.7 46.1 114.0 15.5 54.4 13.5 12.8 47.9 30.7 20.6 48.6 24.9 86.9 75.6 43.5 45.7 15.9 36.9 108.8 22.5 47.1 6.5 28.3 62.3 21.0 92.7 79.5 41.0 42.1 39.5 18.6 32.3 39.5 26.9 14.2 31.6 47.8 50.2 26.4 16.7 130.0 56.9 75.6 42.7 58.7 113.9 39.6 26.5 111.6 32.8 33.1 69.1 45.6 47.3 86.3 34.2 6.7 78.7 23.5 34.0 46.3 50.2 62.8 63.1 48.9 25.5 38.3 39.1 33.2 44.5 1.4 3.3 0.7 3.1 3.7 3.8 3.8 2.2 3.5 4.3 2.7 2.4 3.0 0.6 2.7 1.8 5.8 3.1 1.9 31.6 33.9 29.1 45.8 35.6 33.0 31.5 31.5 32.1 27.3 31.5 31.7 18.8 16.0 6.4 10.4 32.0 22.9 38.1 32.7 25.0 37.8 34.2 36.3 700.2 51.5 25.9 23.9 20.9 82.1 30.8 86.1 146.8 74.6 2.1 12.7 20.9 29.4 45.1 13.2 15.5 51.8 62.1 32.7 46.4 17.3 14.7 31.9 13.9 37.8 57.6 37.0 15.8 62.2 46.8 25.3 43.6 4.8 30.7 30.8 56.9 3.7 105.7 21.9 38.1 12.1 7.2 57.6 60.4 21.8 45.4 68.0 93.4 99.3 9.3 44.8 19.7 17.8 37.2 3.6 45.6 48.3 24.6 66.6 25.6 84.1 105.5 52.9 PTPRH SAP-1 ENSG00000080031 "Protein tyrosine phosphatase receptor type H" Q9HD43 19 55181247-55209506 "Enzymes, Metabolic proteins, Predicted membrane proteins" Apoptosis "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 24.2;intestine: 68.6;stomach 1: 23.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 123.6;Gastric mucus-secreting cells: 60.1;Paneth cells: 94.9;Proximal enterocytes: 113.1" "Cancer enhanced" "Detected in many" "pancreatic cancer: 16.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HHSteC: 11.8;K-562: 15.0;OE19: 30.9;SK-MEL-30: 22.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA042300 Approved Mitochondria NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA042300: AB_10796900" "unprognostic (1.87e-1)" "unprognostic (1.10e-1)" "unprognostic (2.59e-1)" "unprognostic (7.57e-3)" "unprognostic (5.01e-3)" "unprognostic (8.14e-2)" "unprognostic (1.15e-1)" "unprognostic (1.96e-3)" "unprognostic (1.60e-2)" "unprognostic (1.06e-1)" "unprognostic (9.96e-2)" "unprognostic (6.16e-2)" "unprognostic (1.47e-11)" "unprognostic (4.08e-3)" "unprognostic (2.47e-1)" "unprognostic (1.52e-2)" "unprognostic (1.57e-1)" 1.3 16.9 1.7 3.6 4.4 0.0 0.6 5.2 3.0 0.8 0.9 27.9 67.7 0.7 0.1 0.3 0.5 24.2 1.1 1.7 3.4 0.2 13.3 0.1 0.1 7.1 4.9 0.3 4.6 0.1 5.1 0.1 5.7 0.2 21.2 1.3 0.1 0.0 0.0 0.1 68.6 2.1 3.8 22.2 23.6 0.8 4.8 0.0 0.1 0.0 0.1 5.7 0.6 7.2 6.9 4.2 0.0 1.6 1.3 3.6 0.1 0.1 3.6 0.7 1.4 1.8 9.5 0.0 0.3 0.6 8.2 0.0 0.0 0.0 0.8 0.1 0.1 0.5 0.1 4.9 11.8 0.0 4.8 1.0 2.9 2.3 3.6 0.4 0.2 0.0 15.0 0.6 0.0 0.0 0.0 0.3 0.0 30.9 9.8 0.0 0.0 0.5 0.0 0.0 0.4 1.0 0.0 4.2 22.4 0.0 0.0 1.9 0.0 1.0 1.4 0.5 0.1 0.0 3.7 0.0 1.1 0.1 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.7 4.4 5.2 3.0 1.7 3.4 7.1 4.9 5.7 3.8 4.8 7.2 0.3 0.0 0.0 0.0 0.4 1.8 2.8 1.9 0.0 0.1 0.2 0.3 0.6 21.5 3.8 1.8 0.0 0.0 0.0 123.6 0.0 15.5 0.0 1.2 1.0 0.5 4.8 0.0 0.8 25.8 0.1 1.1 60.1 0.5 0.0 4.1 0.7 5.7 0.2 16.8 0.7 20.8 0.0 0.0 1.1 0.3 0.0 0.4 0.0 1.0 0.6 0.2 1.0 0.0 5.8 26.9 94.9 0.0 0.4 3.4 113.1 0.0 4.5 0.5 0.0 3.1 1.8 0.3 0.2 0.0 1.1 0.1 0.5 3.6 18.7 19.7 PUS10 "CCDC139, FLJ32312" ENSG00000162927 "Pseudouridine synthase 10" Q3MIT2 2 60940222-61018259 "Enzymes, Predicted intracellular proteins" "tRNA processing" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 28.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044736, HPA049582" Approved Approved "Nucleoplasm,Nuclear bodies,Mitochondria" No No "Cluster 18: Basophils - Vesicular transport" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Nuclear bodies, Mitochondria" "HPA044736: AB_2679066, HPA049582: AB_2680824" "unprognostic (1.90e-3)" "unprognostic (1.35e-1)" "unprognostic (3.49e-2)" "unprognostic (2.44e-4)" "unprognostic (1.77e-1)" "unprognostic (1.86e-2)" "unprognostic (1.25e-1)" "unprognostic (1.72e-2)" "unprognostic (2.90e-2)" "unprognostic (8.21e-2)" "unprognostic (3.68e-2)" "unprognostic (1.45e-1)" "unprognostic (1.16e-4)" "unprognostic (1.07e-1)" "unprognostic (6.60e-2)" "unprognostic (9.45e-2)" "unprognostic (1.15e-3)" 3.6 3.7 2.7 4.1 2.7 5.1 5.4 2.9 3.4 3.0 3.2 3.6 7.5 3.3 6.4 2.7 3.7 4.1 3.7 2.7 2.5 4.8 15.0 4.9 6.8 2.7 2.6 4.8 4.0 3.9 2.9 3.2 3.0 4.8 4.4 3.9 3.8 2.6 3.1 4.9 9.3 2.7 2.9 4.8 3.4 4.5 2.9 4.5 6.9 1.8 6.8 2.6 1.6 3.6 3.2 1.7 4.9 8.4 4.1 4.6 5.3 6.1 5.5 6.0 5.6 4.8 4.4 12.8 6.3 3.4 5.4 4.2 5.7 4.9 7.4 10.0 2.9 9.0 2.5 15.9 7.6 10.6 5.8 5.3 6.0 4.2 9.4 7.7 7.9 9.1 9.2 6.4 4.6 2.7 8.0 8.7 4.4 3.0 3.5 7.7 6.6 4.7 4.3 6.3 2.8 3.9 5.0 9.7 9.9 3.5 3.4 6.3 5.9 5.7 4.6 3.9 4.7 8.1 3.8 23.6 5.0 6.8 6.5 9.1 1.2 1.1 2.3 1.3 2.5 3.0 1.4 1.6 0.9 1.7 1.7 1.9 2.3 3.1 4.8 3.0 1.0 1.1 2.7 2.7 2.9 3.4 2.7 2.5 2.7 2.6 3.0 2.9 2.9 3.6 6.6 0.0 14.3 20.5 6.8 2.4 3.5 3.3 1.8 6.6 5.9 2.8 5.1 1.5 4.3 3.7 0.0 7.0 8.1 11.9 7.9 3.7 1.6 6.2 4.3 5.8 1.2 5.9 28.3 5.1 4.7 3.1 5.1 8.5 0.0 9.9 4.6 16.3 5.8 1.7 21.7 2.5 4.1 5.7 2.1 1.8 3.1 4.6 1.8 14.0 9.0 7.0 7.2 19.1 24.4 3.5 3.0 1.5 4.6 3.8 26.7 6.3 7.7 7.1 6.6 3.1 3.0 13.9 13.4 3.9 2.3 12.4 6.6 8.2 4.5 10.6 PYCR2 P5CR2 ENSG00000143811 "Pyrroline-5-carboxylate reductase 2" Q96C36 1 225919877-225924340 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Proline biosynthesis" Oxidoreductase "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA056873 Approved Approved Mitochondria NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 51: Myeloid cells - Hemostasis" Mitochondria "HPA056873: AB_2683263" "unprognostic (1.11e-1)" "unprognostic (8.08e-2)" "prognostic unfavorable (5.02e-5)" "unprognostic (2.91e-2)" "unprognostic (1.76e-1)" "unprognostic (1.03e-1)" "unprognostic (4.20e-3)" "unprognostic (1.56e-2)" "unprognostic (6.89e-2)" "unprognostic (1.12e-1)" "unprognostic (9.07e-3)" "unprognostic (1.56e-1)" "prognostic unfavorable (1.42e-6)" "unprognostic (9.69e-2)" "unprognostic (2.61e-1)" "unprognostic (6.44e-2)" "unprognostic (1.16e-3)" 38.0 71.7 53.2 35.8 62.4 47.3 35.8 68.1 54.2 46.4 51.8 39.6 22.3 48.5 26.4 32.3 44.7 22.4 62.3 50.4 61.3 40.2 40.3 38.2 47.2 69.0 61.2 47.9 47.2 42.0 57.0 28.5 66.0 39.6 18.3 34.0 39.6 40.9 66.8 28.3 34.4 25.7 68.6 49.5 38.9 34.4 59.2 43.9 30.0 49.1 33.9 50.3 33.3 72.5 72.6 59.6 35.0 59.1 38.8 40.0 73.2 74.8 46.3 49.7 44.1 77.2 58.3 126.1 156.6 55.0 39.1 81.6 50.5 58.6 28.3 154.6 107.5 120.6 60.2 81.5 59.8 107.9 189.1 38.8 72.3 56.1 64.1 44.1 47.8 103.7 178.4 81.6 50.9 60.5 135.8 120.9 196.0 112.8 80.4 120.2 79.0 263.6 65.2 58.3 44.0 56.7 62.4 48.7 161.0 27.9 62.3 202.0 40.3 38.4 46.5 82.9 104.4 129.9 156.2 127.4 60.7 80.6 109.3 38.4 19.6 39.6 45.5 29.2 47.8 34.4 43.8 42.4 31.3 41.9 74.9 62.4 13.3 67.9 26.3 59.2 44.0 45.1 53.2 62.4 68.1 54.2 50.4 61.3 69.0 61.2 66.0 68.6 59.2 72.5 28.0 19.2 22.8 11.4 31.6 14.8 64.6 53.4 8.0 15.6 24.3 21.2 47.6 20.0 24.8 35.0 14.6 90.6 39.1 12.9 49.0 50.0 8.2 92.8 25.6 26.7 26.5 58.7 4.6 34.0 46.3 23.7 10.2 31.8 38.7 74.9 21.0 16.6 40.0 13.5 5.8 17.8 57.0 20.4 19.8 8.8 38.2 31.5 33.8 8.4 46.4 46.9 46.4 5.5 29.3 29.1 15.8 37.6 23.1 42.1 18.3 35.8 55.4 42.7 26.3 19.8 24.4 40.1 46.2 9.4 12.8 41.7 34.9 44.9 16.1 40.4 PYROXD2 "C10orf33, FLJ23849" ENSG00000119943 "Pyridine nucleotide-disulphide oxidoreductase domain 2" Q8N2H3 10 98383565-98415182 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "eosinophil: 189.8" "Lineage enriched" "Detected in many" 4 "granulocytes: 189.8" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 46.1;U-937: 31.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA037566, HPA037567, HPA067394" Approved Approved Mitochondria NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA037566: AB_10670385, HPA037567: AB_2675550, HPA067394: AB_2685832" "unprognostic (2.35e-2)" "unprognostic (1.38e-1)" "unprognostic (1.79e-2)" "unprognostic (2.41e-2)" "unprognostic (1.10e-3)" "unprognostic (6.76e-2)" "unprognostic (1.27e-2)" "unprognostic (3.38e-2)" "unprognostic (2.69e-1)" "unprognostic (3.34e-1)" "unprognostic (2.20e-1)" "unprognostic (1.63e-1)" "unprognostic (9.05e-2)" "unprognostic (2.74e-1)" "unprognostic (1.33e-1)" "unprognostic (1.26e-2)" "prognostic favorable (3.37e-4)" 10.2 14.5 6.4 2.2 6.9 2.6 8.4 6.7 7.8 9.1 9.6 7.2 2.0 5.5 8.3 2.5 9.4 4.2 10.7 6.3 6.4 6.3 12.2 4.3 2.6 7.3 7.1 9.2 3.5 2.8 4.7 4.2 7.4 10.5 4.7 0.7 22.4 4.1 9.3 2.9 3.7 5.7 7.0 5.1 5.3 3.7 7.1 2.3 8.6 10.4 1.4 9.7 6.3 8.0 3.6 8.9 4.9 0.2 7.6 15.1 1.9 5.8 18.0 3.2 6.1 0.0 12.3 0.0 10.2 6.2 0.9 1.8 1.5 2.0 3.3 0.3 1.4 7.3 16.1 0.8 9.7 0.1 16.2 8.9 2.6 2.6 3.1 46.1 2.5 3.4 0.2 0.2 4.9 11.1 0.2 17.2 1.4 7.0 3.0 2.3 1.9 0.1 4.7 5.5 0.3 0.1 6.4 0.8 4.6 6.7 5.1 8.1 3.3 0.0 3.6 1.1 5.9 1.2 0.8 0.0 5.7 31.5 0.5 5.4 0.3 189.8 6.1 0.0 1.3 0.0 2.1 5.2 1.9 0.2 1.2 3.6 0.3 44.5 0.0 0.3 0.6 1.8 6.4 6.9 6.7 7.8 6.3 6.4 7.3 7.1 7.4 7.0 7.1 8.0 3.8 9.6 5.1 19.9 1.3 0.5 6.1 9.7 4.0 0.4 15.0 18.4 11.2 5.7 9.5 1.8 0.0 5.6 6.5 3.5 7.9 3.8 0.2 4.1 4.9 4.6 1.2 1.7 3.4 2.4 3.8 7.2 11.2 3.2 2.5 11.2 4.6 2.9 9.8 0.0 4.3 4.9 8.2 3.2 6.6 0.9 3.4 2.0 1.8 5.6 1.8 2.3 19.6 1.5 9.5 1.7 1.6 3.8 0.5 2.7 2.2 12.1 12.2 0.8 6.6 9.7 5.9 2.9 1.5 0.8 0.6 1.8 5.4 17.8 6.3 10.0 QDPR "DHPR, PKU2, SDR33C1" ENSG00000151552 "Quinoid dihydropteridine reductase" P09417 4 17460261-17512206 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tetrahydrobiopterin biosynthesis" Oxidoreductase "Disease variant, Phenylketonuria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 752.2;choroid plexus: 301.8" "Cell type enhanced" "Detected in all" "Hepatocytes: 337.6;Muller glia cells: 387.2;Oligodendrocytes: 481.3;Proximal tubular cells: 527.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058951, HPA065649" Enhanced Approved Mitochondria NA NA 2500000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA058951: AB_2683861, HPA065649: AB_2685526" "unprognostic (1.30e-2)" "unprognostic (4.29e-1)" "unprognostic (8.27e-2)" "unprognostic (2.52e-1)" "unprognostic (1.21e-1)" "unprognostic (1.20e-1)" "unprognostic (3.29e-3)" "unprognostic (3.80e-3)" "unprognostic (1.19e-1)" "unprognostic (1.45e-1)" "unprognostic (6.82e-3)" "unprognostic (2.07e-1)" "prognostic favorable (7.84e-6)" "unprognostic (1.58e-1)" "unprognostic (2.60e-1)" "unprognostic (9.01e-2)" "unprognostic (3.19e-1)" 66.6 74.3 515.1 10.2 720.1 15.1 26.4 696.9 571.9 15.8 301.8 21.2 25.6 16.5 40.1 15.6 17.3 17.7 43.4 457.6 578.5 110.1 197.2 23.3 11.9 663.0 752.2 18.3 28.8 49.9 32.7 11.8 688.6 28.7 17.0 40.1 36.3 19.5 108.6 16.2 23.9 17.9 524.9 14.3 23.7 12.4 602.6 13.6 22.1 61.2 13.3 14.5 15.1 663.7 33.1 62.5 30.2 35.8 66.1 32.3 41.5 43.2 22.3 47.5 41.6 52.2 46.4 12.2 28.0 30.3 50.8 18.4 40.3 58.4 33.7 35.3 7.3 34.8 33.4 128.3 37.3 46.2 2.9 40.8 35.6 31.6 40.3 25.9 24.5 33.2 37.0 29.0 50.6 19.2 65.0 77.8 44.8 36.7 45.4 27.0 21.0 52.2 48.2 17.5 47.1 64.3 31.9 6.7 156.6 35.0 15.7 19.0 37.7 23.6 41.1 26.5 38.2 43.1 67.7 85.3 52.0 43.1 41.7 0.3 38.9 3.0 31.3 61.3 29.8 18.6 33.1 32.3 48.3 18.3 37.4 32.6 1.1 29.8 48.4 115.1 20.3 34.4 515.1 720.1 696.9 571.9 457.6 578.5 663.0 752.2 688.6 524.9 602.6 663.7 20.3 28.9 31.5 10.7 14.8 20.0 21.3 32.2 18.8 36.2 37.6 28.3 74.4 50.1 19.5 38.6 8.4 69.6 22.8 13.7 109.5 41.1 1.0 11.8 19.1 17.2 174.3 30.1 23.1 23.4 34.2 27.1 27.5 17.8 25.4 42.3 20.7 337.6 80.3 82.4 21.9 31.1 34.6 38.1 23.9 4.8 22.7 32.2 152.9 12.2 23.4 387.2 16.5 15.1 481.3 16.9 11.6 38.0 23.6 23.2 41.4 527.2 6.2 31.4 26.3 27.5 25.4 3.3 58.9 29.7 16.1 18.3 18.5 90.0 35.7 17.3 QTRT1 TGT ENSG00000213339 "Queuine tRNA-ribosyltransferase catalytic subunit 1" Q9BXR0 19 10701430-10713437 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "tRNA processing" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Intestinal goblet cells: 260.9;Paneth cells: 224.5;Proximal enterocytes: 261.8;Undifferentiated cells: 280.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042695, HPA048651, HPA049440" Approved Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA042695: AB_2678119, HPA048651: AB_2680477, HPA049440: AB_2680767" "unprognostic (6.19e-2)" "prognostic favorable (7.63e-5)" "unprognostic (2.90e-2)" "unprognostic (3.05e-1)" "unprognostic (4.90e-2)" "prognostic favorable (4.90e-4)" "unprognostic (2.52e-1)" "unprognostic (8.76e-3)" "unprognostic (3.88e-1)" "unprognostic (4.81e-3)" "prognostic favorable (2.13e-4)" "unprognostic (1.14e-2)" "prognostic unfavorable (1.13e-6)" "unprognostic (2.04e-2)" "unprognostic (1.66e-1)" "unprognostic (3.13e-1)" "unprognostic (1.01e-3)" 17.2 27.1 11.2 11.8 11.4 13.4 18.1 10.0 15.9 18.4 9.4 20.0 10.3 22.7 2.7 20.5 20.9 7.3 21.4 11.8 11.3 18.3 30.2 12.5 12.2 10.8 10.6 24.4 51.9 9.6 17.6 7.7 11.1 16.9 5.0 6.1 22.3 9.2 20.5 18.3 15.2 6.1 10.8 14.8 20.7 6.4 11.3 7.0 20.7 10.2 5.1 17.6 16.4 11.6 41.5 32.3 14.6 44.1 15.3 18.2 19.7 20.8 18.3 23.8 22.9 25.6 15.0 47.1 50.1 11.5 14.4 26.6 13.8 24.9 7.7 28.1 20.8 30.4 13.3 55.7 26.6 46.4 25.7 27.8 20.3 15.3 22.1 10.5 24.2 25.5 35.0 50.2 11.8 64.2 39.7 56.5 40.3 25.3 53.5 41.2 19.9 72.2 18.8 26.1 48.4 21.6 33.0 33.4 27.8 6.2 21.5 19.0 19.5 35.0 20.3 58.2 49.7 56.7 48.3 23.3 19.3 55.0 44.4 1.9 16.6 0.4 29.6 31.4 37.4 42.0 31.7 26.4 34.0 40.8 33.3 27.5 1.3 43.9 16.6 39.8 37.9 21.3 11.2 11.4 10.0 15.9 11.8 11.3 10.8 10.6 11.1 10.8 11.3 11.6 23.2 0.0 4.5 47.3 36.6 63.7 63.5 59.0 65.4 36.7 42.6 48.6 7.3 30.0 24.5 57.0 50.1 47.8 27.3 157.0 64.6 25.8 1.6 19.8 28.8 24.7 192.5 30.3 32.8 27.6 39.7 33.5 23.9 18.8 16.5 43.7 18.2 33.9 28.8 90.9 31.4 260.9 42.7 15.8 30.9 2.6 50.7 12.8 49.8 8.4 10.5 22.0 7.2 21.6 30.0 13.9 224.5 37.6 53.2 43.6 261.8 80.3 22.6 57.9 19.7 40.7 31.1 12.9 24.6 36.9 41.9 28.0 27.0 67.4 280.7 37.2 RAB11FIP3 "eferin, KIAA0665, Rab11-FIP3" ENSG00000090565 "RAB11 family interacting protein 3" O75154 16 425649-523011 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 151.1" "Cell type enriched" "Detected in many" 5 "Proximal tubular cells: 384.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028088, HPA028631, HPA030086" Enhanced Enhanced "Nucleoplasm,Vesicles,Cytokinetic bridge,Centriolar satellite,Mitochondria" Yes No "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Centriolar satellite" "Nucleoplasm, Cytokinetic bridge, Mitochondria" "HPA028088: AB_10601672, HPA028631: AB_10601853, HPA030086: AB_10669596" "unprognostic (6.65e-2)" "unprognostic (1.84e-2)" "unprognostic (1.51e-1)" "prognostic favorable (1.22e-4)" "unprognostic (2.87e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (9.87e-5)" "unprognostic (6.71e-2)" "unprognostic (4.74e-1)" "unprognostic (9.66e-2)" "prognostic favorable (3.16e-5)" "unprognostic (1.12e-1)" "prognostic favorable (7.99e-4)" "unprognostic (1.39e-1)" "unprognostic (1.77e-1)" "unprognostic (1.58e-1)" "unprognostic (1.44e-1)" 27.9 32.3 18.0 5.3 18.9 7.0 19.5 21.3 22.6 29.6 7.6 35.1 9.0 31.3 5.5 12.3 27.5 7.4 31.4 21.7 14.0 151.1 37.3 25.2 5.8 14.4 15.8 33.8 47.4 15.9 41.5 6.5 15.2 29.9 3.1 6.1 19.3 7.8 52.2 19.5 27.5 7.1 12.7 26.4 22.2 34.6 16.8 5.3 24.8 15.8 3.2 31.7 19.9 19.0 5.9 14.9 14.6 11.9 20.2 13.2 10.0 10.6 11.6 10.7 7.6 11.5 3.0 15.3 11.0 18.7 8.9 5.5 8.9 13.4 3.9 10.8 14.9 7.9 14.8 31.7 20.9 9.5 8.6 12.7 8.8 11.6 9.9 11.7 17.3 10.7 3.5 6.0 14.4 22.5 10.2 15.9 11.7 5.0 6.8 22.8 10.8 4.6 11.3 4.0 13.8 12.0 11.5 13.6 7.5 5.0 7.6 13.9 29.9 14.8 8.8 13.6 7.0 6.9 6.7 18.8 6.5 5.8 11.7 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 18.0 18.9 21.3 22.6 21.7 14.0 14.4 15.8 15.2 12.7 16.8 19.0 9.4 3.2 1.7 36.9 3.8 3.7 0.7 1.1 2.2 7.7 3.5 4.3 12.4 7.2 4.3 5.5 6.2 1.0 5.7 5.9 27.4 1.6 1.2 6.4 8.7 7.1 3.0 1.7 73.5 1.2 0.2 5.5 2.0 13.1 1.3 8.4 17.9 15.9 0.8 21.9 60.3 3.0 0.0 3.7 1.6 2.6 0.6 4.7 0.0 19.7 0.6 7.2 2.1 46.8 40.7 1.4 3.9 1.9 3.4 0.9 8.1 384.2 3.1 7.6 6.6 5.3 5.4 4.0 2.8 0.3 2.3 0.8 4.4 6.1 5.9 0.3 RALGAPA1 "DKFZp667F074, GARNL1, GRIPE, KIAA0884, RalGAPalpha1, Tulip1" ENSG00000174373 "Ral GTPase activating protein catalytic subunit alpha 1" Q6GYQ0 14 35538352-35809304 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 394.0;Inhibitory neurons: 233.9;Oligodendrocyte precursor cells: 239.3;Oligodendrocytes: 412.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000851 Approved Approved Mitochondria,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 21: Non-specific - Transcription" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol Mitochondria "HPA000851: AB_1078945" "unprognostic (1.26e-1)" "unprognostic (1.33e-1)" "unprognostic (8.90e-2)" "unprognostic (6.76e-2)" "unprognostic (1.85e-1)" "unprognostic (1.19e-2)" "unprognostic (7.65e-2)" "unprognostic (1.17e-2)" "unprognostic (2.88e-1)" "unprognostic (3.38e-2)" "unprognostic (1.25e-2)" "unprognostic (5.00e-2)" "prognostic favorable (9.76e-5)" "unprognostic (2.75e-1)" "unprognostic (2.46e-1)" "unprognostic (3.09e-2)" "unprognostic (1.46e-1)" 13.5 18.5 24.0 9.0 28.1 7.1 16.0 36.0 29.0 21.6 18.3 17.6 7.7 16.5 13.8 15.8 17.9 9.4 12.8 24.2 26.3 14.4 13.0 14.1 9.6 26.6 25.5 23.9 16.3 25.5 23.4 7.4 26.2 17.5 14.5 39.4 13.0 10.5 18.4 20.1 14.7 12.6 25.9 12.0 15.8 10.6 26.4 9.7 16.3 10.9 9.0 15.9 18.3 33.6 7.4 8.7 11.0 9.6 16.4 11.4 7.0 5.2 5.4 6.7 6.0 5.2 6.4 7.2 7.2 7.1 8.8 12.0 13.4 10.2 6.2 16.1 5.1 6.7 11.0 26.3 8.4 11.4 10.4 8.6 18.3 5.8 14.1 11.0 9.5 14.2 6.7 17.9 5.9 11.8 8.5 5.4 5.0 18.2 12.9 6.9 6.7 4.6 13.8 11.9 10.2 16.7 11.0 18.9 9.6 10.6 18.0 5.3 8.7 6.5 5.0 7.6 6.5 14.6 14.4 9.3 3.0 7.3 7.2 0.0 0.2 0.0 0.7 0.3 0.9 0.5 0.7 0.9 0.3 0.3 0.4 0.7 0.0 0.7 0.3 0.4 0.8 0.1 24.0 28.1 36.0 29.0 24.2 26.3 26.6 25.5 26.2 25.9 26.4 33.6 40.2 16.0 30.9 162.6 63.9 38.1 28.3 13.9 62.0 86.1 27.7 21.5 19.4 15.7 25.2 23.9 394.0 10.9 105.8 31.0 0.0 12.8 19.5 47.0 38.5 31.4 31.1 14.9 215.3 15.8 5.5 34.6 54.0 50.8 53.4 41.6 18.5 14.8 9.2 52.2 233.9 23.3 16.2 10.0 39.9 8.7 34.2 35.4 19.6 173.3 16.8 30.5 16.5 239.3 412.8 15.9 25.9 29.0 86.3 36.0 26.6 10.4 25.2 119.1 39.5 59.0 37.8 47.0 38.0 55.9 46.2 15.2 80.7 24.0 28.7 27.1 RARS2 "DALRD2, dJ382I10.6, MGC14993, MGC23778, PRO1992, RARSL" ENSG00000146282 "Arginyl-tRNA synthetase 2, mitochondrial" Q5T160 6 87513938-87589987 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Neurodegeneration, Pontocerebellar hypoplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039987, HPA042645" Uncertain Approved Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 1: K-562 - Erythropoiesis" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "HPA039987: AB_2676786, HPA042645: AB_2678097" "unprognostic (1.49e-2)" "unprognostic (1.08e-1)" "unprognostic (5.03e-2)" "unprognostic (6.98e-2)" "unprognostic (9.27e-2)" "unprognostic (5.41e-2)" "unprognostic (6.61e-2)" "unprognostic (4.30e-2)" "unprognostic (1.88e-1)" "unprognostic (1.08e-3)" "unprognostic (8.28e-2)" "unprognostic (2.20e-1)" "unprognostic (7.56e-3)" "unprognostic (1.62e-1)" "unprognostic (1.89e-2)" "unprognostic (5.73e-2)" "unprognostic (7.16e-3)" 24.0 39.6 10.8 15.8 11.8 19.3 21.3 14.7 11.6 21.5 19.2 20.8 17.8 21.8 18.6 17.7 19.7 19.0 22.7 10.4 11.4 20.5 27.9 18.3 16.8 11.5 11.6 18.5 24.0 21.4 17.5 22.2 11.8 18.8 22.7 25.9 20.8 13.6 22.5 18.5 22.6 21.5 11.0 18.5 19.2 25.3 12.5 18.5 20.6 19.3 19.0 20.6 18.2 15.5 19.8 19.1 45.1 49.8 44.6 47.5 31.9 46.6 54.2 30.8 38.6 36.6 21.6 25.0 26.9 47.4 32.0 26.7 37.9 25.8 43.2 18.0 36.0 25.7 24.4 58.7 56.1 30.7 21.3 48.9 24.6 26.4 33.1 44.5 41.0 25.7 59.6 24.4 46.8 35.2 10.0 32.8 29.2 42.3 20.0 19.9 45.9 22.2 38.5 40.1 40.8 54.7 24.8 12.1 33.1 38.2 22.5 45.8 28.1 21.2 16.8 22.8 38.4 25.6 45.1 21.1 32.2 31.8 36.6 18.8 17.8 22.7 16.1 18.6 19.0 15.1 20.4 15.1 15.6 16.2 19.9 16.9 11.9 18.6 20.7 17.9 27.9 15.4 10.8 11.8 14.7 11.6 10.4 11.4 11.5 11.6 11.8 11.0 12.5 15.5 34.4 19.2 15.6 30.0 21.2 17.3 35.4 51.3 12.5 13.9 17.3 16.8 19.9 10.0 37.8 11.0 20.9 31.0 18.1 14.6 45.0 32.9 95.3 23.5 29.3 22.8 9.0 7.4 46.8 46.9 45.5 28.3 12.8 20.3 18.3 27.9 23.6 15.5 20.5 6.7 59.0 23.5 44.7 13.5 14.1 50.6 25.4 15.0 19.6 38.4 22.6 13.6 19.6 56.3 63.9 37.6 21.2 24.0 20.7 30.8 57.2 32.9 24.2 20.3 26.3 18.9 30.0 61.8 33.7 14.1 18.0 39.5 20.6 51.4 27.0 33.9 RASGEF1C FLJ35841 ENSG00000146090 "RasGEF domain family member 1C" Q8N431 5 180100795-180209211 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 21.9;testis: 5.8" "Cell type enriched" "Detected in some" 9 "Microglial cells: 188.3" "Cancer enhanced" "Detected in some" "glioma: 2.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.2;HEK 293: 1.7;MCF7: 2.2;SCLC-21H: 7.6;U-2 OS: 2.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028242 Uncertain Approved Mitochondria NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "HPA028242: AB_10602294" "unprognostic (2.21e-1)" "unprognostic (2.18e-1)" "unprognostic (2.23e-1)" "unprognostic (4.75e-4)" "unprognostic (4.65e-2)" "unprognostic (4.04e-2)" "unprognostic (3.84e-2)" "unprognostic (1.02e-3)" "unprognostic (2.02e-1)" "unprognostic (1.16e-1)" "unprognostic (2.35e-2)" "unprognostic (2.34e-1)" "unprognostic (1.65e-4)" "unprognostic (5.89e-2)" "unprognostic (8.25e-3)" "unprognostic (3.70e-1)" "unprognostic (1.77e-2)" 0.3 0.2 6.2 0.2 16.4 0.0 0.4 21.9 8.5 1.3 0.0 3.4 0.1 0.0 0.1 0.3 0.5 0.3 1.3 7.1 3.2 0.2 0.0 0.0 0.0 7.3 4.4 0.1 0.1 0.0 0.1 0.1 7.5 0.9 0.2 0.3 1.1 0.9 0.0 0.5 0.8 0.1 5.2 0.0 0.7 5.8 4.1 0.0 1.1 0.0 0.0 0.7 1.1 7.6 0.0 0.0 0.2 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.1 0.0 2.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.3 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 2.4 0.0 0.0 0.0 1.3 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 16.4 21.9 8.5 7.1 3.2 7.3 4.4 7.5 5.2 4.1 7.6 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.2 1.8 1.1 0.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 3.4 0.2 0.0 0.5 0.0 0.0 20.2 0.0 0.6 0.1 0.0 0.5 0.0 1.5 0.0 0.0 0.1 0.0 12.5 0.0 0.0 0.0 0.0 3.8 0.0 0.1 0.0 188.3 0.0 0.2 0.0 15.1 19.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 16.7 1.0 0.0 0.0 1.9 0.0 0.5 0.0 0.0 RASSF8 "C12orf2, HoJ-1" ENSG00000123094 "Ras association domain family member 8" Q8NHQ8 12 25959029-26079892 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 59.6" "Cell type enhanced" "Detected in many" "Early spermatids: 606.9;Horizontal cells: 430.7;Late spermatids: 722.1;Microglial cells: 229.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "U-2197: 107.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038163, HPA038164" Uncertain Approved Mitochondria,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 34: Spermatids - Unknown function" "Mitochondria, Cytosol" "HPA038163: AB_2675874, HPA038164: AB_10672621" "unprognostic (2.77e-1)" "unprognostic (1.71e-1)" "unprognostic (3.10e-1)" "unprognostic (6.10e-3)" "unprognostic (3.88e-1)" "unprognostic (3.15e-1)" "unprognostic (6.10e-3)" "unprognostic (8.28e-2)" "unprognostic (2.86e-1)" "unprognostic (6.29e-3)" "unprognostic (2.08e-1)" "unprognostic (1.07e-1)" "unprognostic (7.00e-2)" "unprognostic (1.32e-3)" "unprognostic (3.14e-1)" "unprognostic (2.61e-1)" "unprognostic (4.58e-2)" 11.3 16.3 17.7 7.5 20.1 1.1 7.7 21.6 12.3 17.1 17.0 14.0 2.5 28.3 10.9 7.5 10.9 17.2 13.9 12.2 21.1 22.8 5.8 14.9 2.4 23.7 22.8 30.1 5.9 3.6 6.9 9.0 25.3 16.5 4.9 16.9 4.1 14.0 14.4 3.3 4.3 19.8 21.8 5.9 6.0 59.6 21.1 4.5 11.3 15.6 2.1 10.4 7.5 24.6 9.8 7.7 32.8 4.0 49.9 56.0 45.5 51.6 75.3 21.4 23.5 16.7 2.9 0.7 39.8 56.1 23.7 3.7 7.2 6.1 27.3 3.5 9.6 1.7 19.0 0.8 24.9 6.0 0.4 33.5 5.9 47.7 31.6 33.1 25.9 12.1 1.9 6.7 25.1 13.0 7.1 1.2 32.8 0.2 70.9 9.1 31.7 0.5 12.9 14.4 1.5 23.4 27.3 0.5 25.3 28.3 5.0 5.0 30.9 42.0 21.7 107.9 39.3 2.9 2.0 1.0 38.9 0.5 60.3 0.2 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.4 0.0 1.1 0.0 0.0 17.7 20.1 21.6 12.3 12.2 21.1 23.7 22.8 25.3 21.8 21.1 24.6 22.6 38.5 16.0 139.7 0.7 7.8 50.5 5.6 5.2 17.0 5.2 11.8 34.3 24.3 7.8 22.0 10.4 9.6 10.0 0.1 13.7 10.4 606.9 7.8 50.0 22.1 0.0 0.0 15.1 4.3 21.3 41.3 1.1 12.0 1.3 9.0 16.4 6.7 5.7 430.7 89.7 0.0 2.0 2.2 10.2 722.1 18.0 5.9 14.2 229.5 0.2 31.0 0.0 78.4 92.9 5.2 0.0 15.1 1.9 29.1 0.0 24.5 1.6 11.1 13.1 30.6 20.7 27.9 10.7 1.1 5.4 4.5 3.5 13.2 0.2 13.4 RBFA "C18orf22, FLJ21172, HsT169" ENSG00000101546 "Ribosome binding factor A" Q8N0V3 18 80034389-80050651 "Predicted intracellular proteins" "rRNA processing" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040485, HPA041479" Approved Approved Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 85: Liver - Metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA040485: AB_10795368, HPA041479: AB_10795697" "unprognostic (5.31e-3)" "unprognostic (3.21e-2)" "unprognostic (1.87e-1)" "unprognostic (4.55e-2)" "unprognostic (7.33e-2)" "unprognostic (5.00e-3)" "prognostic unfavorable (2.06e-6)" "unprognostic (2.98e-1)" "unprognostic (7.98e-2)" "unprognostic (7.22e-2)" "unprognostic (4.28e-2)" "unprognostic (3.76e-2)" "unprognostic (2.43e-1)" "unprognostic (3.23e-1)" "unprognostic (1.78e-1)" "unprognostic (3.82e-1)" "unprognostic (5.00e-3)" 18.6 19.9 6.2 9.8 6.1 13.6 17.8 8.1 6.6 13.6 4.7 13.6 12.0 12.4 5.5 17.6 11.0 5.9 18.3 6.3 6.3 14.8 31.3 10.6 8.5 5.8 5.4 10.1 16.7 9.1 8.9 8.3 5.8 11.6 7.9 5.9 12.7 6.8 22.3 20.0 10.9 10.0 5.4 12.4 11.9 12.1 5.8 10.3 11.0 13.3 10.7 13.4 14.2 6.4 28.4 32.6 20.5 20.0 17.5 20.2 27.7 24.0 11.9 25.8 21.9 19.1 22.1 58.6 8.9 16.5 22.6 26.1 21.8 26.1 20.5 22.1 23.9 35.3 24.6 53.0 14.6 55.7 16.7 18.8 24.9 18.6 26.3 11.3 22.4 35.3 19.1 35.7 15.5 30.0 55.6 38.4 22.4 17.7 30.6 38.0 19.6 72.5 26.8 35.2 35.7 21.3 21.0 23.4 17.3 17.0 17.7 29.5 19.7 37.6 37.2 5.5 27.0 14.1 24.5 48.7 22.1 46.2 22.4 0.0 4.8 0.0 6.4 6.5 10.1 8.9 6.5 6.4 7.6 6.5 7.4 6.8 0.2 7.3 10.3 5.7 5.5 5.3 6.2 6.1 8.1 6.6 6.3 6.3 5.8 5.4 5.8 5.4 5.8 6.4 25.4 32.1 10.9 14.0 24.1 18.5 24.4 29.8 25.6 13.5 29.2 32.5 12.2 18.6 24.4 27.6 18.8 50.1 14.8 9.9 31.3 28.4 17.7 23.7 39.0 20.3 20.9 29.9 18.3 24.2 49.9 24.7 19.4 20.9 13.3 34.5 15.7 40.8 24.4 32.0 17.5 21.7 14.2 8.2 20.5 17.0 19.0 15.2 33.8 12.2 9.6 8.0 19.6 19.6 14.1 21.3 7.6 18.4 26.2 23.8 13.7 46.4 19.4 21.8 19.7 17.3 26.3 37.7 49.2 38.2 23.4 24.9 16.7 47.5 25.5 20.9 RCAN2 "DSCR1L1, ZAKI-4" ENSG00000172348 "Regulator of calcineurin 2" Q14206 6 46220736-46491972 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 199.5;tongue: 180.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 255.4;Excitatory neurons: 261.4;Inhibitory neurons: 254.4;Muller glia cells: 183.1;Oligodendrocytes: 294.6;Smooth muscle cells: 138.4" "Cancer enhanced" "Detected in all" "renal cancer: 25.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 17 "gdT-cell: 1.8;memory CD4 T-cell: 1.1;memory CD8 T-cell: 2.2;naive CD8 T-cell: 1.5" "Lineage enriched" "Detected in single" 23 "T-cells: 2.2" "Group enriched" "Detected in some" 6 "fHDF/TERT166: 63.3;HDLM-2: 129.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053880 Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria Nucleoplasm "HPA053880: AB_2682290" "unprognostic (2.82e-1)" "unprognostic (7.76e-2)" "unprognostic (4.13e-2)" "unprognostic (1.14e-1)" "unprognostic (5.55e-3)" "unprognostic (4.52e-2)" "unprognostic (1.29e-3)" "unprognostic (1.86e-3)" "unprognostic (2.26e-1)" "unprognostic (4.33e-1)" "prognostic favorable (2.48e-4)" "unprognostic (1.37e-1)" "prognostic favorable (1.12e-6)" "unprognostic (3.83e-2)" "unprognostic (1.98e-1)" "unprognostic (1.02e-1)" "unprognostic (2.11e-2)" 38.1 12.6 35.7 7.7 41.2 0.0 17.1 31.7 106.3 20.3 0.0 20.1 9.8 17.5 51.5 25.9 17.0 35.1 199.5 34.0 65.0 32.4 4.9 16.3 4.1 69.6 76.0 24.0 11.1 85.5 17.5 0.6 68.8 25.3 22.6 61.6 9.6 27.0 73.3 17.2 19.1 14.0 20.6 7.1 36.5 5.7 65.5 4.7 20.1 180.1 7.0 44.0 21.4 62.3 0.0 0.0 1.6 0.0 0.7 0.2 0.1 1.1 15.1 1.1 0.1 0.0 0.0 0.0 0.8 63.3 0.0 0.1 0.0 0.0 0.3 129.7 0.8 0.0 0.0 0.0 1.0 0.0 0.0 1.2 0.0 0.1 0.1 0.0 0.3 0.3 0.0 0.1 5.1 0.0 0.0 0.2 2.7 0.4 0.4 0.4 13.6 0.1 0.2 0.3 4.9 0.0 0.0 0.0 0.0 3.0 0.0 0.1 0.0 0.1 1.8 0.1 0.2 6.8 0.1 0.0 0.2 0.0 0.4 0.0 0.0 0.0 1.8 0.0 0.0 0.0 1.1 2.2 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.4 35.7 41.2 31.7 106.3 34.0 65.0 69.6 76.0 68.8 20.6 65.5 62.3 7.6 6.4 5.8 13.7 0.6 6.2 4.6 0.0 0.0 24.8 1.8 1.4 255.4 8.6 0.0 3.7 4.2 0.1 0.8 1.0 70.5 5.5 40.2 0.8 0.4 17.1 25.1 0.0 261.4 2.5 0.0 22.2 1.5 0.8 0.0 0.3 0.4 1.2 0.1 30.3 254.4 1.5 34.6 0.3 8.0 14.2 29.2 0.9 32.0 46.9 0.0 183.1 0.0 76.9 294.6 2.9 0.3 50.4 0.4 3.3 0.0 1.9 0.0 9.7 98.6 16.4 138.4 1.5 1.4 0.5 7.4 0.0 4.0 0.8 0.3 1.4 RGS7 ENSG00000182901 "Regulator of G protein signaling 7" P49802 1 240775514-241357230 "Plasma proteins, Predicted intracellular proteins" "GTPase activation, Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 8.0;brain: 28.1;retina: 12.8" "Cell type enhanced" "Detected in some" "Astrocytes: 288.3;Excitatory neurons: 1353.2;Inhibitory neurons: 1095.0;Oligodendrocyte precursor cells: 615.8" "Cancer enhanced" "Detected in some" "glioma: 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+: 6.2;HaCaT: 5.3;hTERT-HME1: 7.2;RH-30: 6.4;SH-SY5Y: 5.6;U-2 OS: 5.9;U-251 MG: 7.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB017561 Enhanced Supported Mitochondria,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 6: Brain - Smell perception" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol Mitochondria "CAB017561: AB_2285043" "unprognostic (6.48e-2)" "unprognostic (4.30e-2)" "unprognostic (4.67e-2)" "unprognostic (6.65e-2)" "unprognostic (7.84e-3)" "unprognostic (4.09e-2)" "unprognostic (1.49e-2)" "unprognostic (3.61e-1)" "unprognostic (1.42e-2)" "unprognostic (2.51e-4)" "unprognostic (3.54e-1)" "unprognostic (2.19e-2)" "unprognostic (2.23e-1)" "unprognostic (2.64e-2)" "unprognostic (2.28e-1)" 0.0 8.0 11.6 0.0 13.5 0.0 0.1 18.9 28.1 0.1 0.0 0.2 0.2 0.2 0.0 0.1 0.0 0.4 0.0 15.9 8.6 2.4 0.4 0.1 0.3 2.5 3.8 0.4 0.5 0.2 2.8 0.0 6.8 0.1 0.1 12.8 0.0 0.5 0.0 0.1 0.1 0.0 2.6 0.2 2.9 5.3 6.4 0.0 0.0 0.0 0.2 0.0 0.0 13.9 0.9 0.0 0.0 0.0 0.2 0.7 0.0 2.5 4.8 6.2 0.4 0.0 0.0 0.0 0.3 3.3 3.4 5.3 0.0 0.0 3.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 7.2 0.5 0.4 0.0 0.0 0.0 1.9 0.0 0.0 0.0 3.3 0.3 0.2 0.0 6.4 0.0 0.0 0.0 5.3 5.6 0.3 0.2 0.2 0.2 0.0 0.0 2.6 0.0 5.9 0.3 7.2 0.0 4.1 0.0 0.9 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 11.6 13.5 18.9 28.1 15.9 8.6 2.5 3.8 6.8 2.6 6.4 13.9 0.0 0.0 0.0 288.3 2.8 0.0 0.1 0.0 0.0 29.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.1 2.3 0.0 3.5 0.2 7.2 0.0 1353.2 0.0 0.0 0.5 1.5 0.1 0.0 10.0 0.4 0.4 0.1 62.2 1095.0 0.4 0.0 0.0 0.3 4.1 0.0 0.1 0.0 29.0 0.0 1.0 0.0 615.8 86.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.1 0.7 6.3 10.8 0.0 0.0 0.0 0.0 0.1 0.1 0.1 RICTOR "AVO3, KIAA1999, MGC39830, PIA" ENSG00000164327 "RPTOR independent companion of MTOR complex 2" Q6R327 5 38937920-39074399 "Predicted intracellular proteins" "Host-virus interaction" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 258.9;Oligodendrocytes: 343.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 30.3" "Lineage enriched" "Detected in all" 5 "granulocytes: 30.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037802, HPA037803" Approved Approved Mitochondria NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 6: Brain - Smell perception" "Cluster 20: HeLa - Mitochondria" "Cluster 9: Photoreceptor cells - Phototransduction" Mitochondria "HPA037802: AB_10672286, HPA037803: AB_2675676" "unprognostic (2.25e-2)" "unprognostic (8.30e-2)" "unprognostic (4.02e-1)" "unprognostic (7.94e-3)" "unprognostic (5.47e-2)" "unprognostic (2.95e-3)" "unprognostic (2.95e-3)" "unprognostic (1.33e-1)" "unprognostic (3.55e-2)" "unprognostic (4.37e-1)" "unprognostic (2.73e-2)" "unprognostic (8.29e-2)" "unprognostic (2.41e-1)" "unprognostic (2.58e-1)" "unprognostic (3.42e-1)" "unprognostic (1.51e-1)" "unprognostic (1.64e-2)" 7.7 5.5 7.3 8.8 10.2 24.5 9.4 17.4 9.9 7.7 0.9 7.1 5.4 9.2 6.3 5.5 6.9 6.2 10.0 8.4 7.2 7.0 7.7 9.9 11.3 9.1 7.0 10.0 6.2 6.7 4.9 8.9 10.6 6.6 6.6 26.3 6.4 5.1 11.7 8.4 7.9 6.8 9.2 10.2 7.0 9.3 7.6 12.8 8.6 11.5 9.2 7.1 7.2 16.9 5.9 10.6 7.6 7.6 9.5 10.8 11.1 8.1 18.7 8.7 8.7 6.5 10.5 9.7 3.0 8.0 13.2 9.5 6.7 8.8 10.5 8.6 6.0 11.4 25.4 7.9 6.1 9.7 14.6 9.2 6.4 10.8 11.8 8.6 14.6 7.8 9.4 18.1 5.9 3.1 9.9 16.0 4.9 3.1 8.2 7.9 13.6 8.6 7.2 9.7 6.4 4.4 21.1 7.8 10.9 7.1 5.4 10.5 12.5 17.6 8.5 7.2 6.1 8.0 5.3 9.5 7.5 12.7 6.6 8.7 1.4 8.5 4.9 1.4 4.0 3.8 4.9 4.3 1.5 4.6 5.2 6.0 30.3 3.7 3.4 5.1 3.3 0.8 7.3 10.2 17.4 9.9 8.4 7.2 9.1 7.0 10.6 9.2 7.6 16.9 32.9 64.1 50.2 72.8 62.4 48.8 39.6 38.7 27.3 69.6 28.6 13.5 38.4 28.6 34.7 27.6 204.3 40.5 65.6 28.0 0.0 25.9 2.3 33.0 31.1 43.0 43.6 73.4 153.8 15.9 20.6 37.4 30.1 35.1 33.0 32.9 49.2 33.0 19.3 52.2 153.9 26.0 22.4 40.6 47.6 5.3 47.5 36.3 33.8 108.7 45.2 28.8 74.2 258.9 343.1 28.1 29.9 32.4 48.7 65.8 30.7 15.3 38.0 176.0 13.1 43.6 34.6 36.5 33.2 18.3 45.0 96.5 70.9 21.3 19.6 74.6 RIMS3 "NIM3, RIM3" ENSG00000117016 "Regulating synaptic membrane exocytosis 3" Q9UJD0 1 40620680-40665682 "Predicted intracellular proteins" "Exocytosis, Neurotransmitter transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "brain: 105.9" "Cell type enhanced" "Detected in many" "Early spermatids: 12.6;Excitatory neurons: 37.7;Inhibitory neurons: 21.1;Late spermatids: 34.4;Muller glia cells: 13.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.5" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Daudi: 77.4;JURKAT: 26.7;SH-SY5Y: 35.2;U-87 MG: 32.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055285 Approved Nucleoplasm,Nucleoli,Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 65: Brain - Ion transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli, Mitochondria" Nucleoplasm "HPA055285: AB_2682771" "unprognostic (3.51e-3)" "unprognostic (7.18e-3)" "unprognostic (4.44e-3)" "unprognostic (1.44e-4)" "unprognostic (3.70e-1)" "unprognostic (2.88e-2)" "unprognostic (1.44e-5)" "unprognostic (2.41e-1)" "unprognostic (1.53e-1)" "unprognostic (2.87e-1)" "unprognostic (2.54e-1)" "unprognostic (7.93e-2)" "unprognostic (1.09e-1)" "unprognostic (2.19e-1)" "unprognostic (3.25e-2)" "unprognostic (3.11e-2)" "unprognostic (2.19e-2)" 1.0 6.2 33.4 1.9 63.8 3.6 2.5 0.0 80.2 1.6 0.0 4.4 0.6 3.5 1.6 2.3 2.7 0.9 2.1 27.0 29.3 1.4 0.4 3.5 1.7 0.7 38.1 1.8 0.7 2.9 1.0 3.2 0.4 2.5 3.1 6.5 1.6 3.3 0.3 2.2 2.2 4.1 2.8 1.2 3.4 3.7 105.9 4.3 2.2 0.5 2.3 2.5 1.5 30.2 4.1 1.6 5.8 6.2 0.3 0.0 0.9 0.1 0.1 1.0 1.2 0.7 1.2 77.4 0.1 0.1 2.8 0.7 3.8 0.7 0.6 13.5 1.9 4.4 0.5 2.1 0.2 0.7 3.5 0.1 3.1 0.2 0.2 0.2 0.3 26.7 3.8 2.9 0.0 7.0 11.7 0.4 3.8 0.7 0.4 5.3 5.3 14.3 1.1 1.0 19.9 35.2 0.8 3.7 2.6 7.7 0.9 21.4 0.1 0.6 5.9 0.1 1.1 0.7 5.9 16.8 32.2 1.3 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.1 0.0 33.4 63.8 0.0 80.2 27.0 29.3 0.7 38.1 0.4 2.8 105.9 30.2 0.0 6.4 0.0 2.6 0.4 0.5 0.2 0.1 0.6 6.1 1.5 2.5 1.8 0.0 0.1 1.8 0.0 0.1 7.3 6.0 0.0 0.9 12.6 0.0 0.0 0.5 0.0 1.3 37.7 1.5 0.1 0.5 0.0 0.1 1.3 10.7 0.0 0.0 2.7 5.0 21.1 4.2 0.0 2.6 1.4 34.4 0.0 1.5 0.0 3.7 0.9 13.4 0.0 4.0 4.5 2.3 1.4 0.7 0.2 0.4 0.0 0.7 0.0 0.7 0.0 1.5 2.5 2.7 2.0 0.1 0.1 0.3 0.9 0.7 1.6 0.2 RNF10 "KIAA0262, RIE2" ENSG00000022840 "Ring finger protein 10" Q8N5U6 12 120533480-120577588 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 286.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052643 Approved Approved Nucleoplasm,Mitochondria No No "Cluster 10: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm Mitochondria "HPA052643: AB_2681897" "unprognostic (1.54e-1)" "unprognostic (3.04e-1)" "unprognostic (5.40e-2)" "unprognostic (2.83e-3)" "unprognostic (1.09e-2)" "unprognostic (3.58e-2)" "prognostic unfavorable (5.30e-5)" "unprognostic (5.02e-2)" "unprognostic (3.06e-1)" "unprognostic (1.68e-1)" "unprognostic (1.93e-1)" "unprognostic (2.31e-1)" "unprognostic (3.43e-2)" "unprognostic (2.41e-1)" "unprognostic (2.18e-1)" "unprognostic (4.10e-2)" "unprognostic (2.40e-1)" 79.5 104.3 99.0 52.7 101.2 184.8 68.1 97.2 135.0 63.9 108.8 90.1 58.8 61.6 96.1 103.0 58.5 50.1 191.2 101.7 98.4 108.3 81.7 74.4 53.6 99.0 102.9 65.6 75.2 75.8 71.3 65.9 97.8 69.0 65.8 76.6 68.1 61.7 307.2 77.8 61.2 77.8 99.3 78.7 81.0 96.8 100.9 57.9 60.7 208.8 69.5 73.2 69.3 107.2 109.7 141.6 68.3 109.3 130.9 103.0 80.6 100.7 113.9 81.8 86.4 117.1 49.3 129.5 89.4 167.3 64.0 73.9 126.6 136.5 116.0 127.5 71.0 132.1 77.5 123.0 175.3 120.0 89.5 105.5 155.0 115.1 156.8 141.8 168.5 95.7 134.2 86.7 124.3 125.3 79.4 131.1 104.0 101.7 139.9 69.8 87.5 185.4 164.4 221.1 66.9 72.7 140.0 89.5 78.9 94.2 144.2 68.6 134.8 59.3 65.7 95.5 65.9 74.7 146.8 90.8 97.5 80.2 65.0 154.2 53.8 173.8 45.5 45.8 48.9 35.7 44.7 52.4 60.0 31.2 39.5 40.6 118.0 46.1 54.3 30.7 60.7 52.9 99.0 101.2 97.2 135.0 101.7 98.4 99.0 102.9 97.8 99.3 100.9 107.2 56.2 25.6 32.6 30.3 54.0 61.9 51.1 27.1 52.3 39.9 63.8 42.9 99.3 32.9 28.4 47.8 22.9 62.1 58.9 93.5 164.4 49.7 72.7 54.1 53.2 45.9 49.2 286.5 43.1 58.7 69.4 47.8 64.7 78.9 36.8 42.0 42.8 48.8 36.9 55.5 42.9 50.3 34.6 52.5 63.1 41.7 56.8 54.7 56.9 16.9 48.7 43.3 56.7 32.2 52.4 59.8 49.1 54.9 71.2 63.1 73.8 70.0 21.6 54.5 52.6 52.3 55.0 118.0 55.2 74.5 65.8 111.8 59.1 74.1 47.3 77.8 RNF115 "CL469780, ZNF364" ENSG00000265491 "Ring finger protein 115" Q9Y4L5 1 145738868-145824095 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 6.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019130 Approved Approved Nucleoli,Mitochondria NA NA "Cluster 34: Basophils - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoli, Mitochondria" "HPA019130: AB_1859220" "unprognostic (3.44e-2)" "unprognostic (2.47e-3)" "unprognostic (2.24e-1)" "unprognostic (1.09e-1)" "unprognostic (5.48e-2)" "unprognostic (1.90e-1)" "prognostic unfavorable (2.95e-4)" "unprognostic (2.29e-2)" "unprognostic (1.46e-2)" "unprognostic (1.35e-1)" "unprognostic (2.64e-2)" "unprognostic (7.29e-2)" "unprognostic (1.44e-2)" "unprognostic (3.23e-1)" "unprognostic (4.77e-2)" "unprognostic (2.46e-2)" "unprognostic (1.08e-1)" 8.9 5.0 7.7 4.6 7.3 7.5 7.5 16.1 9.0 7.1 6.1 9.0 3.4 12.2 4.1 5.7 7.9 4.7 24.9 7.7 6.8 5.6 5.1 5.9 5.0 6.3 6.8 5.5 5.3 6.8 5.3 3.5 6.6 7.3 3.7 13.9 5.9 5.2 32.1 6.1 5.5 11.1 5.7 5.0 5.8 3.9 7.5 5.0 6.1 25.3 4.7 7.9 5.6 7.1 11.0 4.5 5.4 3.9 9.6 12.5 4.2 8.1 15.1 5.9 7.1 4.9 3.8 7.7 9.0 11.7 5.7 7.5 6.0 5.5 6.3 7.7 3.9 6.1 5.9 4.6 6.1 9.7 13.7 7.3 4.8 6.0 7.1 6.7 7.7 5.9 6.1 12.2 10.8 8.3 7.1 6.0 6.8 7.0 9.4 6.7 5.4 6.4 11.6 3.6 5.3 7.4 6.6 8.0 6.3 6.6 8.9 9.1 9.4 8.4 6.6 5.1 8.7 10.2 10.3 8.0 4.2 6.4 5.4 6.4 1.0 1.6 1.4 0.8 1.2 1.5 1.0 1.4 0.8 1.2 1.0 1.4 0.7 1.6 0.8 1.1 1.0 0.7 7.7 7.3 16.1 9.0 7.7 6.8 6.3 6.8 6.6 5.7 7.5 7.1 168.4 16.0 29.2 61.7 43.5 20.6 32.6 24.4 23.9 101.3 35.9 29.1 152.5 38.6 27.0 18.4 114.7 26.8 155.6 13.2 33.2 44.8 68.5 52.9 45.4 72.3 27.1 60.6 91.2 80.3 28.7 60.8 28.1 55.8 31.7 39.1 71.7 33.1 37.2 82.4 77.6 23.5 28.5 41.5 36.2 25.3 39.4 38.9 39.2 84.3 71.0 64.4 90.6 81.4 83.9 52.4 18.8 80.9 90.5 76.0 22.5 46.6 29.6 111.1 59.2 60.2 53.5 76.5 63.7 23.7 18.0 19.8 75.7 65.2 23.6 40.2 RNF138 "NARF, STRIN" ENSG00000134758 "Ring finger protein 138" Q8WVD3 18 32091874-32131561 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway, Wnt signaling pathway" "DNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 96.0;testis: 119.3" "Group enriched" "Detected in many" 15 "Early spermatids: 982.8;Late spermatids: 3827.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041101 Approved Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "HPA041101: AB_10805837" "unprognostic (2.37e-2)" "unprognostic (4.63e-3)" "unprognostic (2.03e-3)" "unprognostic (1.01e-1)" "unprognostic (2.34e-1)" "unprognostic (2.93e-2)" "unprognostic (1.47e-2)" "unprognostic (9.64e-2)" "unprognostic (1.29e-2)" "unprognostic (1.90e-2)" "unprognostic (6.90e-2)" "unprognostic (1.27e-2)" "unprognostic (6.15e-2)" "unprognostic (9.52e-3)" "unprognostic (2.77e-1)" "unprognostic (9.58e-2)" "unprognostic (1.90e-1)" 13.7 7.3 7.6 17.4 9.3 96.0 14.5 13.8 11.9 12.4 10.7 23.5 16.7 14.3 8.5 14.9 19.4 13.6 5.9 6.9 8.7 9.7 21.6 13.3 24.2 8.0 8.6 14.9 16.4 11.2 7.5 15.3 8.5 10.5 20.2 8.9 9.9 7.9 6.9 8.8 17.3 11.6 8.3 21.6 14.2 119.3 8.2 28.9 11.8 6.8 19.8 13.3 8.6 12.4 28.3 16.4 66.4 33.2 8.5 17.5 37.6 28.3 15.8 34.7 39.8 19.4 19.3 67.9 34.3 18.6 22.3 28.9 35.1 31.9 47.1 37.7 58.8 53.5 19.2 24.1 33.3 149.3 45.3 17.1 31.3 38.3 53.8 19.9 35.9 59.3 74.7 27.0 22.7 26.6 101.1 66.5 74.4 48.4 22.6 102.5 41.7 39.3 31.9 20.7 75.0 37.5 37.7 21.7 30.1 30.2 14.0 62.2 27.8 41.5 30.5 10.3 32.2 44.4 64.5 117.9 22.6 81.6 41.5 25.0 64.4 63.3 25.0 48.7 32.2 34.6 54.5 35.9 62.5 39.2 102.8 66.9 64.7 42.8 42.0 26.6 44.3 68.3 7.6 9.3 13.8 11.9 6.9 8.7 8.0 8.6 8.5 8.3 8.2 12.4 27.9 16.0 19.7 15.3 65.9 69.3 33.7 11.8 71.2 6.7 32.4 18.0 8.3 24.3 16.8 16.5 0.0 28.3 51.6 43.0 17.6 17.6 982.8 35.6 20.4 29.4 29.9 48.8 25.9 18.4 21.6 21.3 26.0 28.7 22.8 8.4 22.5 16.8 24.8 8.4 28.0 20.8 20.3 25.5 52.3 3827.9 29.5 34.7 26.6 23.4 27.1 9.9 20.6 22.6 36.4 12.9 23.9 22.2 32.4 32.7 16.4 14.5 23.0 5.2 32.9 23.1 26.0 158.1 128.3 51.4 52.1 8.9 59.3 9.9 29.9 37.5 RPL7L1 dJ475N16.4 ENSG00000146223 "Ribosomal protein L7 like 1" Q6DKI1 6 42879616-42889925 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046049, HPA050478" Approved Nucleoli,Mitochondria NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 52: Non-specific - Transcription" "Nucleoli, Mitochondria" "HPA046049: AB_10964167, HPA050478: AB_2681138" "unprognostic (1.03e-3)" "unprognostic (4.37e-2)" "unprognostic (3.37e-1)" "unprognostic (7.97e-2)" "unprognostic (7.73e-3)" "unprognostic (4.26e-2)" "prognostic unfavorable (8.53e-5)" "unprognostic (2.56e-1)" "unprognostic (2.98e-2)" "unprognostic (3.78e-2)" "unprognostic (2.08e-1)" "unprognostic (1.39e-1)" "unprognostic (2.94e-2)" "unprognostic (7.53e-2)" "unprognostic (1.06e-1)" "unprognostic (7.31e-3)" "unprognostic (4.58e-2)" 37.2 39.5 26.1 31.7 28.0 22.6 40.2 27.2 33.5 28.2 20.6 30.4 25.4 30.0 34.0 35.4 34.2 21.5 30.8 28.7 27.3 37.7 48.4 25.2 34.4 23.7 24.1 33.6 32.2 45.4 29.1 31.7 24.2 33.7 34.1 20.0 28.0 27.7 45.5 33.9 23.4 33.4 24.0 27.1 28.6 16.1 26.6 37.1 35.9 44.4 42.8 35.6 27.0 25.9 155.6 48.4 84.2 135.5 77.5 99.5 57.1 121.3 87.8 115.0 94.6 120.4 57.6 231.4 107.0 102.6 93.4 72.5 193.4 147.6 189.4 121.9 144.6 123.7 64.5 109.9 85.2 192.5 91.6 102.5 110.6 151.0 144.7 77.5 114.7 100.2 243.1 77.6 106.2 113.3 110.5 124.2 85.1 472.2 70.3 124.9 94.3 147.1 89.7 96.6 160.1 97.8 103.7 78.2 131.3 66.1 105.0 183.1 110.1 110.5 91.9 88.4 211.3 96.7 163.8 343.2 61.7 178.7 117.7 7.3 13.1 12.4 16.0 15.8 20.3 14.9 15.7 17.0 12.5 17.4 16.5 16.0 2.8 19.7 14.9 14.5 14.3 13.6 26.1 28.0 27.2 33.5 28.7 27.3 23.7 24.1 24.2 24.0 26.6 25.9 56.2 76.9 103.0 12.7 69.3 57.1 89.3 70.6 67.7 62.6 49.2 61.8 42.2 61.5 71.2 42.3 33.3 88.2 77.7 23.9 86.1 92.2 12.6 68.4 96.6 71.6 94.4 73.0 25.9 66.9 84.1 67.5 42.8 44.9 51.2 120.6 51.8 65.0 53.0 72.3 23.3 44.4 54.9 45.0 34.4 12.5 79.2 44.5 30.2 8.4 75.8 78.6 64.9 12.5 15.6 81.3 30.8 71.5 56.1 83.8 25.1 79.8 71.3 69.7 52.6 89.9 64.0 54.9 75.6 65.8 60.2 80.0 65.6 117.8 52.5 58.9 RPS6KA6 RSK4 ENSG00000072133 "Ribosomal protein S6 kinase A6" Q9UK32 X 84058346-84188199 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 75.3;Inhibitory neurons: 70.7;Oligodendrocyte precursor cells: 31.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NTERA-2: 8.1;PC-3: 7.9;RH-30: 9.9;SH-SY5Y: 9.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002852, HPA003904" Uncertain Supported Nucleoplasm,Nucleoli,Mitochondria NA NA "Cluster 35: T-regs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Mitochondria" Nucleoli "HPA002852: AB_1079854, HPA003904: AB_1079853" "unprognostic (1.17e-1)" "unprognostic (1.02e-2)" "unprognostic (3.44e-1)" "unprognostic (4.93e-4)" "unprognostic (1.71e-1)" "unprognostic (3.04e-3)" "unprognostic (2.09e-2)" "unprognostic (2.50e-1)" "unprognostic (2.86e-1)" "unprognostic (4.88e-2)" "unprognostic (3.38e-3)" "unprognostic (2.88e-1)" "unprognostic (2.12e-9)" "unprognostic (4.44e-3)" "unprognostic (1.30e-2)" "unprognostic (2.34e-2)" "unprognostic (8.49e-3)" 0.4 2.0 2.6 0.5 3.1 0.1 1.7 3.2 3.0 2.0 2.6 2.9 1.2 1.7 3.1 0.8 2.2 1.1 0.6 2.7 3.4 5.7 0.6 0.6 0.2 2.7 2.4 2.6 0.9 7.0 5.8 0.3 2.2 2.8 2.3 7.0 1.7 2.7 1.6 2.0 1.3 1.0 1.5 0.4 1.7 1.5 2.4 1.0 8.1 0.4 0.3 1.3 1.4 2.0 0.0 2.4 2.6 0.0 2.4 2.2 0.0 5.2 2.7 2.3 1.9 1.9 2.0 0.0 0.0 2.6 0.0 0.1 6.4 4.6 5.1 0.0 3.5 0.0 0.1 0.0 2.7 0.0 0.0 1.4 0.0 0.0 2.4 3.0 0.6 0.0 0.0 0.1 2.0 0.0 1.1 0.1 8.1 0.0 7.9 0.0 9.9 0.0 0.5 5.4 0.0 9.4 0.0 3.4 0.0 3.8 1.4 0.0 0.0 0.1 2.4 0.0 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.6 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.6 0.0 2.6 3.1 3.2 3.0 2.7 3.4 2.7 2.4 2.2 1.5 2.4 2.0 0.3 9.6 2.7 6.2 0.7 0.3 5.3 0.3 3.4 21.1 3.6 3.4 2.6 12.8 1.9 18.4 25.0 2.6 0.1 6.7 1.9 0.5 0.7 1.9 1.2 1.2 25.0 2.7 75.3 1.2 0.7 2.2 2.0 0.9 0.0 21.8 1.1 1.3 0.2 1.7 70.7 3.6 0.0 0.0 0.0 0.4 4.4 0.5 0.0 3.7 0.1 2.1 1.0 31.2 5.8 1.3 3.4 6.0 0.0 9.2 1.8 4.3 3.7 18.2 0.0 4.9 1.5 8.4 6.2 2.5 0.4 2.3 0.9 2.0 6.5 5.2 RRP15 "CGI-115, KIAA0507" ENSG00000067533 "Ribosomal RNA processing 15 homolog" Q9Y3B9 1 218285293-218337983 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024639 Approved Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome,Mitochondria" Yes No "Cluster 30: Non-specific - Translation" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli rim, Mitotic chromosome" "Nucleoplasm, Mitochondria" "HPA024639: AB_1844368" "unprognostic (2.68e-2)" "unprognostic (4.94e-2)" "unprognostic (2.04e-1)" "unprognostic (1.22e-1)" "unprognostic (5.19e-2)" "unprognostic (1.33e-2)" "prognostic unfavorable (4.26e-5)" "unprognostic (7.87e-2)" "unprognostic (1.07e-1)" "unprognostic (2.18e-1)" "unprognostic (3.65e-3)" "unprognostic (2.54e-1)" "unprognostic (2.76e-3)" "unprognostic (1.52e-1)" "unprognostic (5.77e-1)" "unprognostic (1.11e-2)" "unprognostic (3.23e-2)" 4.0 2.6 1.7 3.3 1.7 4.1 4.7 2.5 2.4 3.0 1.4 3.0 2.1 3.7 2.7 3.0 2.9 1.9 4.9 1.8 1.9 3.4 3.5 2.8 3.7 1.4 2.0 3.8 2.9 4.5 1.8 3.6 1.6 3.1 2.9 2.2 2.6 2.4 9.6 3.5 2.4 3.4 1.5 2.9 2.6 2.4 1.8 2.6 3.5 7.7 3.5 3.9 2.8 1.9 9.8 7.2 7.9 5.7 5.6 7.8 6.7 9.8 7.3 10.0 7.2 14.1 8.8 14.0 13.1 7.6 6.7 8.7 13.5 13.0 16.6 5.7 10.1 10.9 6.6 7.8 11.6 17.0 5.6 5.4 7.8 13.1 17.4 4.4 6.6 6.5 22.7 4.4 11.4 8.9 11.3 8.3 15.7 7.8 14.8 7.8 4.9 13.8 8.0 8.9 9.0 13.1 8.3 15.3 15.0 9.3 11.0 12.1 9.3 8.0 7.6 14.3 18.3 5.4 8.9 14.4 9.1 8.1 13.1 0.3 0.8 0.1 1.6 1.3 2.3 2.4 2.0 1.4 1.2 2.3 2.6 2.6 0.2 1.6 1.1 1.7 1.3 0.7 1.7 1.7 2.5 2.4 1.8 1.9 1.4 2.0 1.6 1.5 1.8 1.9 33.7 32.1 28.1 7.5 36.0 65.3 33.6 28.7 24.5 31.1 32.6 31.0 68.4 22.8 25.0 36.8 10.4 38.1 32.7 13.5 27.4 39.7 17.0 22.6 47.3 27.9 12.1 41.0 18.4 52.2 59.1 32.2 19.9 28.5 31.0 18.6 21.8 44.2 33.6 26.9 16.1 20.8 6.1 17.3 18.5 4.6 37.6 17.4 21.4 7.5 20.8 21.2 24.7 7.5 9.0 36.8 9.0 24.8 13.0 34.9 5.2 37.2 11.7 23.6 26.3 72.1 33.0 59.7 69.1 24.3 47.6 18.1 26.4 20.4 32.1 23.0 RSAD1 "FLJ11164, HemW" ENSG00000136444 "Radical S-adenosyl methionine domain containing 1" Q9HA92 17 50478860-50485974 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA022436, HPA022967, HPA024459" Approved Approved "Mitotic chromosome,Mitochondria" Yes NA "Cluster 39: Non-specific - mRNA processing" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 52: Non-specific - Transcription" Mitochondria "Mitotic chromosome" "HPA022436: AB_2180789, HPA022967: AB_1856484, HPA024459: " "unprognostic (8.21e-2)" "unprognostic (4.11e-3)" "unprognostic (3.72e-2)" "unprognostic (1.83e-2)" "unprognostic (3.49e-2)" "unprognostic (2.93e-2)" "unprognostic (6.01e-2)" "unprognostic (1.07e-2)" "unprognostic (2.52e-1)" "unprognostic (1.13e-2)" "prognostic favorable (5.04e-4)" "unprognostic (1.06e-1)" "unprognostic (1.65e-2)" "unprognostic (4.89e-2)" "unprognostic (2.95e-1)" "unprognostic (7.85e-2)" "unprognostic (3.22e-2)" 23.9 41.4 34.7 16.4 37.8 12.8 23.5 37.5 43.4 36.9 32.9 24.3 17.1 24.2 17.5 17.3 24.5 12.5 43.3 34.4 33.9 40.9 44.0 21.1 19.8 34.5 34.9 31.8 48.9 27.5 23.6 12.4 35.1 25.2 17.6 21.2 27.3 14.9 66.0 22.2 23.9 14.4 34.2 31.8 32.5 14.2 35.4 18.4 29.1 57.0 17.8 26.1 23.6 37.0 13.0 43.2 20.3 33.7 34.0 27.6 7.2 22.2 21.6 27.9 23.5 43.0 16.1 34.9 48.0 15.6 27.6 12.1 23.2 31.0 23.9 38.9 42.0 47.0 20.5 42.4 23.7 28.6 31.7 20.2 33.7 18.6 35.7 23.0 27.5 84.1 36.9 32.3 23.7 30.3 48.1 20.9 8.2 54.6 45.9 19.6 23.2 31.6 34.0 19.4 11.1 37.9 5.7 26.3 29.7 25.6 39.6 28.7 19.6 29.0 30.8 22.3 26.4 50.0 37.6 13.5 21.8 40.3 20.6 1.1 4.2 3.8 8.5 4.4 8.5 4.5 7.3 8.4 4.9 6.9 9.4 9.5 0.0 6.6 4.2 5.4 6.2 5.7 34.7 37.8 37.5 43.4 34.4 33.9 34.5 34.9 35.1 34.2 35.4 37.0 15.1 3.2 13.1 18.3 16.0 10.1 4.4 7.2 19.4 14.8 12.1 12.8 29.4 12.8 7.7 16.5 2.1 21.4 24.1 10.8 23.5 14.4 8.8 5.3 10.4 12.4 25.2 12.0 24.0 29.5 11.1 13.1 12.2 7.4 3.8 15.8 10.0 18.5 16.1 8.4 21.5 11.7 8.2 7.2 6.1 7.4 15.5 9.6 17.8 16.9 12.5 32.1 19.6 13.6 12.4 11.8 6.2 10.9 18.7 6.5 11.1 11.1 3.8 7.8 13.1 16.0 11.3 11.5 21.9 10.6 9.9 10.1 18.7 43.6 12.9 3.4 RTKN B5 ENSG00000114993 Rhotekin Q9BST9 2 74425835-74442422 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 149.6;liver: 124.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "NK-cell: 2.3;plasmacytoid DC: 6.6" "Group enriched" "Detected in many" 4 "dendritic cells: 6.6;NK-cells: 2.3" "Cell line enhanced" "Detected in many" "Hep G2: 96.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030259 Approved Approved Nucleoplasm,Mitochondria No No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria Nucleoplasm "HPA030259: AB_10601484" "unprognostic (4.09e-1)" "unprognostic (1.28e-1)" "unprognostic (1.20e-2)" "unprognostic (2.47e-1)" "unprognostic (3.51e-2)" "unprognostic (1.47e-3)" "unprognostic (5.32e-2)" "unprognostic (1.95e-2)" "unprognostic (2.57e-2)" "unprognostic (9.43e-3)" "unprognostic (4.99e-2)" "unprognostic (2.48e-2)" "unprognostic (2.96e-2)" "unprognostic (7.15e-2)" "unprognostic (1.85e-1)" "unprognostic (5.81e-2)" "unprognostic (1.23e-3)" 9.8 8.3 69.5 5.0 104.1 0.6 11.3 85.4 84.6 13.5 51.9 20.3 31.8 8.7 3.5 20.8 12.7 14.2 17.3 72.0 84.3 54.4 124.7 10.3 3.1 100.4 95.5 7.7 30.8 20.7 14.7 11.8 95.7 19.1 12.6 1.9 26.0 9.5 12.8 32.0 25.3 6.3 73.4 5.2 15.3 3.3 93.5 6.3 19.5 7.5 5.3 8.3 16.6 149.6 50.4 15.5 19.5 56.3 11.8 13.7 82.1 7.6 9.9 11.0 8.0 76.3 26.8 0.3 21.2 7.4 13.6 67.2 7.3 48.6 5.3 9.9 31.3 12.0 2.8 96.7 7.2 0.0 0.1 8.4 37.7 9.5 30.0 20.2 5.5 0.7 6.2 0.3 16.5 35.8 1.9 10.1 20.9 70.9 30.3 11.1 60.6 7.6 52.4 0.3 19.0 18.8 20.7 79.3 45.2 17.5 44.6 4.4 0.6 20.5 14.0 9.3 10.6 4.8 3.7 1.8 19.6 0.1 19.5 0.0 0.0 0.0 0.2 0.0 0.2 0.7 0.1 0.2 0.6 1.0 0.0 0.1 0.0 2.3 0.0 6.6 0.0 0.4 69.5 104.1 85.4 84.6 72.0 84.3 100.4 95.5 95.7 73.4 93.5 149.6 4.3 9.6 11.8 4.9 2.0 20.0 22.1 37.2 19.4 0.1 14.4 12.2 3.1 28.6 18.3 11.0 2.1 46.7 4.5 21.7 21.5 43.0 0.7 12.6 6.1 8.8 30.7 1.3 0.5 20.1 8.3 8.9 15.8 26.0 1.3 4.9 5.3 40.1 10.1 0.0 0.9 20.1 18.3 2.2 3.8 1.5 12.8 1.1 28.4 3.7 0.7 6.9 5.2 34.7 48.2 30.5 31.0 8.6 1.4 35.4 44.7 54.7 5.8 0.4 6.6 36.9 3.9 1.1 5.6 12.9 21.6 33.4 2.5 3.1 30.5 15.6 RTKN2 "bA531F24.1, Em:AC024597.2, FLJ39352, PLEKHK1" ENSG00000182010 "Rhotekin 2" Q8IZC4 10 62183035-62268844 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "lung: 77.5" "Group enriched" "Detected in many" 10 "Alveolar cells type 1: 1753.2;Early spermatids: 480.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebral cortex: 1.6" "Immune cell enriched" "Detected in some" 8 "T-reg: 16.7" "Lineage enriched" "Detected in single" 72 "T-cells: 16.7" "Cell line enhanced" "Detected in many" "A-431: 45.2;HaCaT: 35.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA037946, HPA038446" Enhanced Approved Nucleoplasm,Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 19: Lung - Lung function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 11: Alveolar cells - Smell perception" Nucleoplasm Mitochondria "HPA037946: AB_10795398, HPA038446: AB_10796218" "unprognostic (2.33e-1)" "unprognostic (2.59e-1)" "unprognostic (2.52e-2)" "unprognostic (1.52e-2)" "unprognostic (1.26e-1)" "unprognostic (8.92e-3)" "unprognostic (6.66e-5)" "unprognostic (7.81e-3)" "unprognostic (2.33e-2)" "unprognostic (3.24e-1)" "unprognostic (3.72e-2)" "unprognostic (9.48e-4)" "unprognostic (3.70e-11)" "unprognostic (3.95e-2)" "unprognostic (9.34e-3)" "unprognostic (4.68e-3)" "unprognostic (1.55e-1)" 0.2 0.1 0.1 1.7 0.4 0.8 1.1 0.6 1.6 1.5 0.0 1.6 1.3 0.9 0.1 7.1 0.2 0.7 0.1 0.2 0.0 0.4 0.2 77.5 3.5 0.0 0.0 0.2 0.1 0.4 0.8 1.3 0.0 1.1 2.0 0.9 1.4 0.2 0.0 1.2 1.5 0.4 0.0 1.4 1.2 7.6 0.1 3.9 0.6 0.0 3.4 1.2 3.1 0.5 45.2 2.6 23.2 10.8 0.0 0.1 5.6 6.4 7.4 7.2 11.2 18.7 8.9 0.1 2.8 2.6 7.3 35.3 13.1 1.0 7.4 6.4 8.9 7.5 5.4 7.8 0.1 9.9 5.6 0.3 0.6 8.8 0.9 3.8 1.1 11.8 0.5 0.2 9.7 5.6 19.8 13.1 9.8 6.7 8.7 16.9 24.9 0.1 4.6 19.5 12.6 14.5 4.3 14.8 6.0 6.8 13.4 5.6 0.1 3.3 20.8 0.2 16.5 0.1 0.1 17.2 4.2 0.0 5.2 0.1 0.0 0.0 1.1 0.0 0.0 0.0 2.0 0.4 0.1 0.1 0.6 0.3 0.2 0.1 0.0 0.1 16.7 0.2 0.1 0.4 0.6 1.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.4 1753.2 45.8 0.3 1.5 4.7 10.2 3.0 0.0 0.7 5.0 3.6 0.5 1.5 10.9 0.0 0.0 9.0 2.0 1.9 0.0 1.6 480.3 5.6 1.4 0.7 1.8 1.7 21.5 1.6 7.2 2.9 7.1 10.8 3.8 12.9 1.1 0.0 2.4 0.0 2.5 8.5 6.1 0.6 2.9 102.8 2.1 2.1 1.8 1.0 0.4 0.3 0.0 0.5 1.0 15.4 0.7 1.9 3.3 9.7 0.5 1.9 2.8 0.5 0.0 0.6 3.4 23.5 24.6 26.2 1.8 2.1 17.4 2.9 7.0 97.3 S100A10 "42C, ANX2LG, CAL1L, CLP11, P11" ENSG00000197747 "S100 calcium binding protein A10" P60903 1 151982915-151993859 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 1760.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 3820.4;Langerhans cells: 3945.6;Pancreatic endocrine cells: 4570.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 2005.4;monocytes: 1235.2;T-cells: 1180.0" "Cell line enhanced" "Detected in all" "OE19: 4936.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003340, CAB025484" Enhanced Approved Mitochondria Yes No 270000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" Mitochondria "CAB025484: , HPA003340: AB_1856531" "unprognostic (2.13e-1)" "unprognostic (1.51e-3)" "unprognostic (1.01e-1)" "unprognostic (3.15e-1)" "unprognostic (6.20e-2)" "prognostic unfavorable (3.33e-4)" "prognostic unfavorable (1.00e-4)" "prognostic unfavorable (2.66e-5)" "unprognostic (1.09e-2)" "unprognostic (9.48e-2)" "prognostic unfavorable (3.88e-4)" "unprognostic (1.36e-1)" "prognostic unfavorable (3.80e-8)" "unprognostic (1.09e-1)" "unprognostic (1.50e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (3.84e-4)" 775.1 376.9 71.1 244.8 76.6 133.7 519.6 75.5 139.8 478.0 78.5 867.3 461.4 110.1 56.7 1760.5 188.7 212.4 340.9 72.4 132.8 735.0 157.7 689.8 133.3 148.2 105.0 234.0 145.0 36.3 71.0 326.9 108.5 164.9 924.2 51.3 422.8 105.0 106.0 483.4 448.0 288.2 98.2 111.2 189.1 145.8 138.8 118.3 143.5 145.4 289.8 338.4 803.1 110.3 1251.3 1085.9 3.4 241.6 1351.4 1711.3 972.5 730.1 912.1 613.8 606.5 1975.4 1671.4 2.3 689.1 1208.0 661.7 2227.5 337.0 2786.6 495.3 242.5 127.1 163.8 461.5 468.1 507.0 60.2 126.7 470.8 2195.5 660.6 738.6 487.6 1326.0 78.9 2.9 3.6 753.8 940.0 11.0 376.5 163.6 4936.7 1671.4 1.6 242.4 27.1 2348.3 317.0 11.1 9.5 1259.2 374.3 539.8 1213.0 882.2 130.5 1654.9 285.5 737.2 1362.3 459.2 34.4 7.8 225.2 1709.5 51.7 977.8 359.5 1235.2 299.7 425.7 758.7 443.3 232.4 652.3 539.0 2005.4 140.1 237.7 363.1 43.6 355.0 664.7 329.6 1180.0 1313.4 71.1 76.6 75.5 139.8 72.4 132.8 148.2 105.0 108.5 98.2 138.8 110.3 1197.3 2554.5 537.7 3.9 244.0 1594.8 1171.4 2183.2 795.6 11.6 241.1 281.4 111.2 693.4 994.6 950.9 4.2 1271.5 476.2 3820.4 1524.1 1811.7 314.2 901.0 104.6 1061.2 1078.1 114.2 0.4 2105.0 527.4 1751.3 432.8 1270.7 289.5 840.0 864.5 206.9 1023.1 16.8 0.9 1723.1 272.6 795.2 3945.6 274.2 647.1 1338.1 1632.8 28.1 1544.2 24.8 285.3 4.0 0.6 4570.5 3391.8 64.7 244.5 2782.5 2146.1 495.6 620.3 32.5 144.7 801.6 529.5 30.4 115.9 1940.1 1242.0 375.8 801.0 38.5 1998.0 2290.6 SAMD1 ENSG00000141858 "Sterile alpha motif domain containing 1" 19 14087851-14091036 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041662, HPA049059" Uncertain Approved Mitochondria,Cytosol "Intracellular and membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" Cytosol Mitochondria "HPA041662: AB_2677605, HPA049059: AB_2680616" "unprognostic (2.93e-2)" "prognostic favorable (7.41e-4)" "unprognostic (8.43e-2)" "unprognostic (3.30e-1)" "unprognostic (1.56e-2)" "unprognostic (1.72e-2)" "prognostic unfavorable (1.96e-5)" "unprognostic (2.66e-1)" "unprognostic (9.92e-2)" "unprognostic (3.86e-3)" "unprognostic (9.26e-3)" "unprognostic (4.00e-1)" "prognostic unfavorable (7.98e-5)" "prognostic favorable (8.31e-4)" "unprognostic (1.68e-2)" "unprognostic (3.29e-2)" "unprognostic (2.45e-1)" 24.7 18.1 53.2 18.3 51.9 22.3 21.2 49.0 50.5 29.9 33.9 32.3 20.1 30.0 8.7 37.0 24.7 8.2 37.6 48.6 49.6 25.8 24.2 24.5 21.4 57.0 51.6 27.5 24.8 8.0 14.9 10.8 54.4 21.8 14.2 7.1 20.2 14.0 50.9 39.7 29.4 11.7 51.7 38.2 28.6 26.3 52.6 44.5 20.6 22.6 17.7 29.4 30.4 54.0 73.2 54.8 47.3 67.3 28.7 29.7 71.8 39.3 9.4 39.5 31.7 41.5 35.3 125.1 51.2 25.6 18.9 57.9 51.5 29.5 19.5 84.3 42.8 55.5 73.7 76.0 25.9 33.1 33.1 20.7 47.5 27.4 9.2 37.6 23.5 79.6 67.9 33.8 22.9 110.2 69.0 129.2 96.7 53.0 47.9 92.1 41.9 91.8 33.5 35.2 86.5 86.1 34.8 46.6 26.6 25.0 29.6 70.0 26.1 68.7 62.1 69.5 50.7 62.0 58.1 105.2 41.0 89.0 28.4 0.2 1.3 2.5 0.8 0.5 1.0 2.1 0.9 1.0 1.2 1.4 1.2 0.9 0.2 3.7 0.5 0.9 1.1 0.8 53.2 51.9 49.0 50.5 48.6 49.6 57.0 51.6 54.4 51.7 52.6 54.0 42.0 3.2 6.7 0.7 10.9 11.5 4.6 14.4 18.8 31.4 25.2 31.4 11.9 21.5 5.5 11.0 6.2 3.9 22.4 48.6 1.9 11.2 0.3 24.4 21.6 19.4 24.7 43.6 0.3 11.1 9.3 14.3 9.7 24.5 8.2 15.2 13.6 13.8 15.5 52.2 0.4 24.0 6.1 25.7 16.1 2.2 19.3 19.6 10.6 0.0 11.3 19.4 2.1 1.0 0.9 13.0 18.9 18.8 13.3 6.6 23.6 6.6 10.6 8.5 13.1 7.5 18.8 0.8 20.4 29.2 17.2 1.8 14.1 8.2 30.5 4.8 SAMD13 ENSG00000203943 "Sterile alpha motif domain containing 13" Q5VXD3 1 84298366-84389957 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.5;choroid plexus: 26.9;intestine: 22.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 20.3;Intestinal goblet cells: 18.0;Oligodendrocytes: 16.4;Paneth cells: 33.2;Spermatocytes: 22.5;Undifferentiated cells: 21.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 15 "basophil: 12.5" "Lineage enriched" "Detected in single" 15 "granulocytes: 12.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA058929 Enhanced Approved Mitochondria NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA058929: AB_2683855" "unprognostic (3.78e-2)" "unprognostic (4.93e-2)" "unprognostic (8.51e-3)" "unprognostic (7.55e-2)" "prognostic favorable (1.14e-8)" "unprognostic (1.78e-1)" "unprognostic (1.65e-6)" "unprognostic (2.05e-1)" "unprognostic (5.50e-2)" "unprognostic (2.80e-3)" "unprognostic (9.42e-2)" "unprognostic (3.29e-1)" "unprognostic (1.98e-7)" "unprognostic (3.99e-2)" "unprognostic (1.81e-1)" "unprognostic (1.17e-1)" "unprognostic (7.56e-3)" 0.9 3.4 22.3 1.5 30.7 2.8 2.4 11.3 25.7 1.6 26.9 19.5 3.4 1.7 4.1 0.8 4.1 1.8 2.4 19.6 29.0 1.4 0.4 0.9 1.2 29.0 29.4 0.3 1.8 1.2 1.0 0.8 27.7 4.0 22.0 0.8 17.6 2.1 6.2 1.2 3.8 2.5 29.9 1.1 6.1 13.1 35.5 2.8 9.8 3.0 0.6 1.8 0.4 32.5 0.5 2.3 1.1 3.5 3.6 3.3 2.3 0.3 0.2 0.3 0.2 0.0 3.4 3.6 6.3 0.1 0.7 0.4 0.4 1.2 0.5 2.0 1.7 1.3 1.7 0.3 0.8 4.4 0.0 1.3 1.6 0.1 1.0 2.5 8.2 7.8 0.5 1.1 1.0 1.1 5.1 0.5 3.5 2.9 2.3 0.5 2.5 1.5 6.5 2.1 1.4 5.1 0.1 0.1 8.1 1.4 1.0 4.1 1.4 1.4 0.3 0.3 1.0 2.4 0.5 6.3 0.3 3.8 1.1 12.5 0.3 0.0 0.0 0.5 0.2 0.2 0.0 0.0 0.7 0.7 0.3 0.4 0.1 0.5 0.3 0.8 0.0 0.3 22.3 30.7 11.3 25.7 19.6 29.0 29.0 29.4 27.7 29.9 35.5 32.5 1.7 0.0 0.6 2.0 0.3 0.4 0.7 0.7 0.6 1.2 3.8 2.9 1.0 2.8 1.1 1.8 0.0 4.5 0.1 20.3 5.9 2.1 5.6 5.4 1.6 1.6 11.4 6.1 5.2 0.6 0.6 1.4 3.6 4.7 5.7 2.0 3.3 0.1 1.5 0.0 5.8 18.0 0.0 2.4 1.6 5.8 1.8 1.4 8.8 6.5 0.4 2.7 0.0 7.1 16.4 1.1 33.2 2.6 0.1 2.0 3.8 2.9 1.1 0.1 0.0 1.8 0.7 22.5 5.5 2.2 0.3 0.8 0.7 4.1 21.3 1.2 SARDH "DMGDHL1, SDH" ENSG00000123453 "Sarcosine dehydrogenase" Q9UL12 9 133663560-133739955 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "epididymis: 47.9;liver: 114.4;pancreas: 43.2" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 120.6" "Cancer enriched" "Detected in many" 8 "liver cancer: 18.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "memory CD4 T-cell: 3.3;naive CD4 T-cell: 6.7;T-reg: 8.8" "Lineage enriched" "Detected in single" 16 "T-cells: 8.8" "Cell line enhanced" "Detected in many" "AN3-CA: 17.4;Hep G2: 31.1;MOLT-4: 22.5;RH-30: 18.5;RPMI-8226: 39.1;SH-SY5Y: 14.7" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA057267, HPA058086" Approved Approved Mitochondria NA NA 230000 "Cluster 20: T-cells - T-cell receptor" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA057267: AB_2683388, HPA058086: AB_2683601" "unprognostic (3.64e-2)" "unprognostic (4.87e-2)" "unprognostic (2.31e-2)" "unprognostic (1.38e-1)" "prognostic unfavorable (4.62e-4)" "unprognostic (5.83e-2)" "unprognostic (1.42e-3)" "unprognostic (2.21e-1)" "unprognostic (1.58e-1)" "unprognostic (1.43e-1)" "unprognostic (2.23e-1)" "unprognostic (1.74e-1)" "unprognostic (7.74e-3)" "unprognostic (2.78e-1)" "unprognostic (3.48e-1)" "unprognostic (9.73e-2)" "unprognostic (1.30e-2)" 1.1 2.2 3.6 2.5 3.5 0.9 0.8 1.9 3.9 2.6 0.7 1.1 1.8 2.0 47.9 0.6 1.9 1.3 2.4 3.3 3.5 12.0 114.4 2.6 4.1 4.4 3.1 3.0 43.2 2.1 4.1 0.9 3.4 2.3 0.4 0.6 5.3 1.8 0.6 0.4 1.3 0.9 2.9 1.3 3.0 0.7 4.2 4.3 1.6 0.3 2.4 1.1 1.0 3.1 0.0 0.1 1.4 17.4 0.1 0.5 2.3 0.1 0.7 0.9 1.1 0.3 0.2 0.0 2.4 0.3 2.2 0.1 0.0 0.3 0.7 0.0 0.3 2.5 0.0 31.1 1.9 0.1 0.3 4.2 0.0 2.0 0.1 0.4 0.2 13.1 0.1 0.4 11.1 3.2 22.5 2.4 2.8 1.7 0.2 1.6 18.5 39.1 0.0 0.1 1.7 14.7 0.0 0.4 3.9 0.8 2.4 0.2 0.1 3.3 3.0 0.3 0.0 0.3 0.0 1.3 2.1 1.4 0.1 0.3 0.1 0.1 0.3 0.0 0.8 0.0 3.3 0.8 0.0 0.3 6.7 1.2 0.5 0.1 0.0 0.3 8.8 1.4 3.6 3.5 1.9 3.9 3.3 3.5 4.4 3.1 3.4 2.9 4.2 3.1 0.1 0.0 1.9 6.8 0.4 0.3 0.4 0.0 1.2 0.1 0.2 0.8 0.8 0.0 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 1.0 0.8 1.2 5.7 1.5 1.1 0.1 2.3 0.0 0.3 1.3 0.8 2.9 120.6 0.1 0.0 0.7 0.0 0.0 1.6 0.6 0.8 4.7 0.2 0.0 1.9 0.0 4.2 1.0 0.5 0.3 0.1 0.0 3.0 0.7 0.3 0.0 21.3 0.0 0.3 0.0 1.6 3.5 0.1 0.8 0.0 0.1 0.0 4.2 1.6 0.0 0.2 SARS2 "FLJ20450, mtSerRS, SARS, SARSM, SerRSmt, SERS, SYS" ENSG00000104835 "Seryl-tRNA synthetase 2, mitochondrial" Q9NP81 19 38915266-38930763 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 40.1;Late spermatids: 56.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA052730, HPA056957" Approved Uncertain Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Mitochondria" Vesicles "HPA052730: AB_2681929, HPA056957: AB_2683286" "unprognostic (3.20e-3)" "unprognostic (1.17e-1)" "unprognostic (1.38e-1)" "unprognostic (3.53e-3)" "unprognostic (1.08e-1)" "unprognostic (1.88e-3)" "unprognostic (4.38e-3)" "unprognostic (1.22e-1)" "unprognostic (2.57e-2)" "unprognostic (8.62e-3)" "unprognostic (8.36e-2)" "unprognostic (1.67e-1)" "unprognostic (5.62e-3)" "unprognostic (2.50e-2)" "unprognostic (1.82e-1)" "unprognostic (9.24e-2)" "unprognostic (2.69e-2)" 7.3 17.3 4.2 7.2 4.7 9.3 8.2 4.4 6.8 9.7 3.6 10.1 9.3 9.3 2.8 14.3 8.5 5.9 12.4 4.7 4.4 14.6 18.7 6.6 9.8 5.0 4.4 9.8 15.9 7.8 11.9 7.6 5.3 12.2 5.3 2.3 11.3 6.2 16.4 12.3 10.2 5.1 4.2 12.0 11.9 10.7 4.4 7.5 14.4 11.5 6.6 9.4 9.6 5.4 17.6 47.3 15.5 10.7 5.8 13.3 23.7 10.7 12.6 23.1 17.7 36.0 18.4 17.2 16.3 12.5 9.7 13.9 14.7 29.2 5.3 12.7 24.4 33.7 17.7 32.0 15.4 29.1 31.9 20.7 13.5 14.5 7.6 9.5 14.2 26.3 29.9 14.2 10.6 28.4 21.4 20.7 18.5 21.6 8.5 31.2 16.4 18.6 20.5 36.2 29.1 18.1 14.2 32.7 8.9 4.6 21.8 19.1 11.4 13.7 17.7 11.7 15.1 11.0 7.1 13.2 10.9 18.5 13.8 0.0 8.0 1.0 14.2 14.4 11.5 12.0 10.7 14.7 25.2 10.7 7.5 8.6 0.5 14.0 13.7 9.9 13.4 8.9 4.2 4.7 4.4 6.8 4.7 4.4 5.0 4.4 5.3 4.2 4.4 5.4 2.7 6.4 7.9 6.2 8.4 4.2 3.8 8.3 3.4 8.0 7.0 5.3 8.1 7.2 6.8 5.5 8.4 40.1 5.6 8.9 15.6 15.5 15.7 3.6 3.6 3.8 11.4 13.2 6.8 12.7 23.0 4.8 9.7 3.9 5.7 7.4 6.1 10.1 12.9 5.0 6.7 9.2 10.2 6.7 4.2 56.9 4.7 4.8 3.6 1.9 7.7 3.1 5.2 1.5 3.1 8.4 5.6 4.9 10.1 2.6 7.4 10.3 5.1 13.4 0.0 2.7 4.2 1.9 8.2 12.8 4.1 29.1 7.4 10.6 17.8 3.2 SBK3 SgK110 ENSG00000231274 "SH3 domain binding kinase family member 3" P0C264 19 55540656-55545543 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 32.5;tongue: 15.1" "Cell type enriched" "Detected in single" 5 "Cardiomyocytes: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 5.0;CACO-2: 1.8;CAPAN-2: 2.9;K-562: 1.2;NTERA-2: 1.3;RH-30: 2.2" "Not detected" "Not detected" HPA078322 Approved Mitochondria NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 43: Cardiomyocytes - Nuclear processes" Mitochondria "HPA078322: AB_2732379" "unprognostic (2.15e-1)" "unprognostic (1.99e-3)" "unprognostic (2.71e-1)" "unprognostic (1.39e-3)" "unprognostic (7.52e-2)" "unprognostic (2.83e-1)" "unprognostic (5.47e-5)" "unprognostic (4.64e-3)" "unprognostic (7.24e-2)" "unprognostic (1.65e-1)" "unprognostic (3.38e-1)" "unprognostic (3.08e-3)" "unprognostic (1.21e-2)" "unprognostic (4.92e-2)" "unprognostic (2.41e-1)" "unprognostic (1.79e-1)" 2.5 0.0 0.0 0.1 0.0 0.0 1.0 0.4 0.0 0.3 0.0 0.1 0.4 0.2 0.0 2.0 0.2 0.3 32.5 0.0 0.0 0.4 0.1 0.5 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.0 0.3 0.2 0.0 0.0 0.5 0.0 6.5 0.2 0.2 0.2 0.1 0.0 0.4 0.2 0.1 0.0 0.5 15.1 0.0 0.3 0.1 0.1 0.0 5.0 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 1.8 2.9 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.5 0.0 0.0 1.3 0.0 0.3 0.1 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SCO2 "MYP6, SCO1L" ENSG00000284194 "Synthesis of cytochrome C oxidase 2" O43819 22 50523568-50526461 "Disease related genes, Human disease related genes, Predicted membrane proteins" Chaperone "Cardiomyopathy, Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 112.2;Paneth cells: 131.5;Proximal enterocytes: 110.7;Suprabasal keratinocytes: 98.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046943, HPA056254" Uncertain Approved Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA046943: AB_2732536, HPA056254: AB_2683080" 16.8 10.3 14.0 13.4 13.8 36.5 7.8 14.4 16.8 6.8 18.2 22.0 25.6 3.6 4.7 12.3 15.8 7.7 10.3 14.3 14.4 8.1 18.4 14.4 9.1 18.8 19.1 1.8 11.5 7.2 1.5 8.3 17.5 5.1 10.5 0.1 21.3 6.7 10.2 11.0 19.7 12.7 16.4 11.4 10.2 4.1 17.4 11.2 2.3 10.1 10.3 13.0 2.5 17.4 37.4 29.9 1.3 12.5 17.7 24.2 18.7 19.5 24.1 38.0 32.8 35.3 17.8 42.7 19.7 22.6 9.6 36.0 19.3 31.5 6.1 7.6 82.5 13.8 20.2 46.7 44.6 43.8 18.3 38.4 48.6 19.4 15.8 10.6 24.4 5.8 15.6 32.9 16.8 55.7 13.3 76.5 11.0 15.5 54.8 26.1 7.5 65.0 29.6 21.3 16.6 23.7 24.4 70.7 63.5 1.3 26.1 24.7 25.8 16.3 22.6 30.2 22.2 26.1 15.6 29.2 35.7 28.7 14.5 19.1 21.8 12.2 43.9 19.9 42.2 40.1 38.9 44.1 34.9 33.4 29.2 32.6 21.6 27.7 21.1 56.2 37.0 37.7 14.0 13.8 14.4 16.8 14.3 14.4 18.8 19.1 17.5 16.4 17.4 17.4 0.0 3.2 2.7 2.9 20.0 85.7 21.6 75.5 44.3 7.3 0.1 0.0 16.8 21.5 31.4 0.0 2.1 0.0 5.3 112.2 0.0 0.0 15.1 0.1 0.2 13.8 25.8 14.1 2.7 0.0 0.0 14.1 24.5 0.1 15.9 0.0 18.2 53.5 0.0 11.8 2.7 63.2 48.8 28.2 63.6 25.6 16.4 29.2 42.7 5.6 47.3 5.5 25.7 5.5 1.4 0.1 131.5 10.9 32.1 40.0 110.7 0.1 42.6 7.1 0.0 30.4 29.5 17.3 35.7 56.1 98.9 0.0 14.9 0.1 90.7 22.3 SDC3 "N-syndecan, SYND3" ENSG00000162512 "Syndecan 3" O75056 1 30869466-30908758 "Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 140.3" "Cell type enhanced" "Detected in many" "Astrocytes: 64.6;Endometrial stromal cells: 59.8;Kupffer cells: 174.8;Late spermatids: 82.4;Oligodendrocyte precursor cells: 108.6" "Group enriched" "Detected in all" 5 "glioma: 115.2;melanoma: 102.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "SK-MEL-30: 249.5;WM-115: 342.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017087, CAB025786, HPA048085" Approved Approved Nucleoplasm,Mitochondria Yes No "Cluster 42: Non-specific - Transcription" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 17: WM-115 - Nervous system development" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria Nucleoplasm "CAB025786: , HPA017087: AB_1857706, HPA048085: AB_2680256" "unprognostic (1.42e-3)" "unprognostic (5.52e-2)" "unprognostic (1.20e-1)" "unprognostic (4.55e-2)" "unprognostic (1.79e-2)" "unprognostic (1.87e-1)" "unprognostic (1.79e-3)" "unprognostic (2.83e-1)" "prognostic favorable (2.36e-4)" "unprognostic (9.77e-2)" "unprognostic (5.14e-2)" "unprognostic (1.65e-2)" "prognostic unfavorable (1.71e-4)" "unprognostic (6.45e-2)" "unprognostic (2.74e-1)" "unprognostic (9.80e-3)" "unprognostic (1.46e-1)" 33.9 99.1 103.9 22.9 123.9 3.0 17.9 97.0 105.4 36.5 38.1 57.3 12.3 62.3 12.3 17.6 29.8 30.0 22.7 91.6 111.1 10.4 22.3 22.5 36.4 140.3 121.2 9.3 7.5 13.2 11.8 18.1 107.9 26.9 14.6 27.2 15.9 52.7 27.1 10.1 16.5 66.2 112.4 91.0 19.7 3.3 124.4 6.4 9.8 9.1 7.6 32.7 13.4 91.9 12.9 10.4 80.4 36.5 60.6 14.8 13.8 31.4 48.0 15.0 9.5 2.0 12.3 0.9 68.6 95.3 21.8 16.3 8.7 7.6 10.0 5.7 6.3 0.0 4.1 1.8 56.9 0.3 8.2 35.4 35.9 1.0 15.4 86.6 20.1 3.6 6.2 0.5 30.6 15.0 0.3 0.2 36.4 10.2 9.4 0.8 75.2 2.8 19.7 14.9 28.9 17.5 40.3 5.7 249.5 50.8 5.7 6.1 19.3 18.6 28.2 2.0 7.5 0.1 0.5 0.9 1.9 0.2 342.9 1.1 0.3 0.2 0.1 0.6 0.2 0.1 0.1 0.2 0.2 0.2 0.2 0.2 0.5 0.4 0.4 0.2 0.2 0.2 103.9 123.9 97.0 105.4 91.6 111.1 140.3 121.2 107.9 112.4 124.4 91.9 37.3 0.0 2.2 64.6 0.5 2.5 3.4 4.7 4.0 9.6 14.9 25.5 4.9 14.3 2.6 47.8 0.0 2.1 0.2 0.8 0.0 10.7 17.7 14.1 59.8 17.9 3.0 0.0 14.7 3.1 3.4 16.6 3.1 28.6 0.0 17.5 20.3 1.0 14.3 0.0 13.9 1.1 6.1 174.8 3.1 82.4 2.1 24.4 19.6 18.7 4.0 2.5 1.0 108.6 6.8 6.0 1.3 7.9 1.5 8.5 0.0 0.6 0.4 27.8 0.0 1.1 9.1 0.7 0.4 1.3 2.3 3.6 2.3 15.4 1.6 5.7 SDHAF3 "ACN9, DC11, LYRM10, Sdh7" ENSG00000196636 "Succinate dehydrogenase complex assembly factor 3" Q9NRP4 7 97117698-97181763 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 148.7;Early spermatids: 136.0;Proximal tubular cells: 150.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA020515, HPA020523" Approved Approved Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA020515: , HPA020523: AB_2670464" "unprognostic (3.94e-2)" "unprognostic (9.11e-2)" "unprognostic (6.51e-2)" "unprognostic (2.51e-2)" "unprognostic (1.39e-1)" "unprognostic (1.61e-2)" "unprognostic (9.60e-3)" "unprognostic (3.21e-2)" "unprognostic (3.74e-2)" "unprognostic (3.07e-3)" "unprognostic (4.27e-2)" "unprognostic (1.10e-1)" "unprognostic (7.67e-3)" "unprognostic (2.82e-1)" "unprognostic (3.79e-3)" "unprognostic (2.34e-1)" "unprognostic (8.45e-2)" 12.4 17.5 9.3 12.4 9.8 16.7 18.7 10.5 13.3 15.0 13.5 20.7 19.9 12.4 22.2 15.0 14.6 13.0 27.0 9.4 11.2 33.5 32.1 8.4 18.5 10.6 10.4 10.7 18.4 12.2 3.6 9.6 11.0 14.8 20.3 16.4 22.0 12.0 29.0 14.1 17.4 12.2 11.6 11.2 18.3 14.5 10.2 24.5 19.0 25.6 14.5 12.8 3.7 12.1 36.6 27.6 24.5 82.3 15.8 12.8 14.8 15.8 7.6 15.6 22.8 5.0 30.7 57.4 40.1 14.1 20.7 13.4 49.6 38.8 33.7 44.2 59.6 34.6 24.8 54.8 23.8 89.4 16.0 24.3 30.3 25.7 32.0 11.6 14.5 57.2 99.5 1.6 34.8 0.0 94.5 126.7 37.3 74.1 34.6 21.0 14.0 83.7 26.0 24.9 63.8 40.7 38.5 47.9 55.5 33.9 0.4 31.6 16.0 4.2 53.2 88.6 10.7 41.4 87.0 139.5 14.6 144.7 51.9 30.0 21.4 8.0 26.5 26.3 36.3 36.3 33.3 39.1 27.9 32.1 45.9 44.4 20.2 23.9 26.7 82.6 33.2 37.9 9.3 9.8 10.5 13.3 9.4 11.2 10.6 10.4 11.0 11.6 10.2 12.1 24.4 19.2 12.5 8.5 34.4 0.0 23.1 0.0 29.0 13.8 38.6 44.4 37.9 18.6 6.8 25.8 4.2 35.2 31.3 7.2 148.7 30.6 136.0 31.3 20.6 17.3 13.3 32.6 16.6 39.1 30.0 20.1 29.0 21.4 5.1 22.2 16.4 55.9 31.1 10.1 14.3 24.2 0.0 20.1 0.0 20.7 22.7 20.2 0.0 9.4 13.9 44.8 36.0 14.6 18.5 24.0 29.1 24.8 30.9 17.0 35.1 150.9 16.0 19.5 32.9 19.5 20.4 32.7 49.3 53.5 0.0 9.6 26.3 45.6 39.8 25.0 SDHAF4 "C6orf57, Sdh8" ENSG00000154079 "Succinate dehydrogenase complex assembly factor 4" Q5VUM1 6 70566917-70589569 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031824 Supported Approved Nucleoplasm,Mitochondria "Intracellular and membrane" No No "Cluster 28: Myeloid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 7: Non-specific - Mitochondria" Mitochondria Nucleoplasm "HPA031824: AB_10602113" "unprognostic (8.72e-2)" "unprognostic (1.64e-1)" "unprognostic (4.95e-2)" "unprognostic (9.96e-2)" "unprognostic (4.58e-1)" "unprognostic (2.02e-1)" "unprognostic (2.17e-1)" "unprognostic (1.81e-1)" "unprognostic (1.15e-1)" "unprognostic (1.42e-3)" "unprognostic (3.18e-2)" "unprognostic (3.17e-1)" "prognostic favorable (1.95e-5)" "unprognostic (2.45e-2)" "unprognostic (9.37e-2)" "unprognostic (3.05e-1)" "unprognostic (9.94e-2)" 11.2 12.3 7.1 4.2 7.5 4.3 10.5 6.8 10.5 6.6 7.3 6.8 5.0 5.8 9.3 7.5 10.3 4.2 14.5 7.6 9.4 12.5 8.5 5.4 6.0 6.9 6.3 6.4 6.6 14.4 12.7 6.8 7.3 7.6 6.7 10.0 8.7 5.4 23.6 8.6 5.4 4.2 5.8 5.6 7.0 5.3 7.8 6.4 7.3 10.6 5.2 6.8 6.7 7.6 13.3 4.2 18.8 11.6 9.0 13.6 3.5 7.1 5.1 3.4 5.0 3.8 11.3 9.1 12.7 3.8 8.0 2.3 6.2 5.9 5.2 18.3 4.3 6.6 1.8 3.9 15.3 6.3 5.1 9.6 19.3 2.6 14.8 11.6 8.0 14.8 4.2 13.9 11.0 9.0 5.9 15.7 8.8 6.5 4.5 6.4 12.6 10.8 14.9 4.4 16.8 12.1 4.3 2.1 9.6 8.0 9.6 16.5 6.3 3.5 2.7 2.8 7.7 6.2 4.5 3.1 3.9 15.1 8.5 4.0 4.6 4.4 3.4 4.3 3.3 3.7 3.7 4.1 5.1 4.7 3.9 3.8 3.3 4.7 4.6 6.2 4.2 3.0 7.1 7.5 6.8 10.5 7.6 9.4 6.9 6.3 7.3 5.8 7.8 7.6 5.4 12.8 13.9 4.9 3.3 0.0 7.9 0.0 3.4 7.4 6.5 7.5 21.3 10.0 5.6 7.3 8.4 10.5 5.0 2.9 23.5 9.1 5.5 20.2 8.2 5.0 3.6 2.5 7.7 11.6 8.5 6.6 2.6 6.0 5.1 6.1 4.2 11.8 10.0 18.5 7.5 5.8 0.0 5.3 0.0 2.5 12.5 6.2 0.0 2.8 10.1 10.1 3.1 12.1 7.7 13.2 5.3 6.8 2.2 9.5 6.2 16.8 13.8 6.4 13.1 5.1 4.9 10.0 6.1 5.7 0.0 5.1 3.9 6.1 5.3 8.0 SDS SDH ENSG00000135094 "Serine dehydratase" P20132 12 113392445-113426301 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Gluconeogenesis Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 34 "liver: 1024.6" "Cell type enhanced" "Detected in some" "Hepatocytes: 364.6;Hofbauer cells: 199.4;Langerhans cells: 111.9;Macrophages: 93.7;monocytes: 97.6" "Cancer enriched" "Detected in all" 31 "liver cancer: 165.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "myeloid DC: 11.6" "Lineage enriched" "Detected in single" 15 "dendritic cells: 11.6" "Cell line enhanced" "Detected in some" "HMC-1: 1.7;SK-BR-3: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA039230 Uncertain Approved Mitochondria,Cytosol NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 3: HMC-1 - Innate immune response" "Cluster 15: Hepatocytes - Hemostasis" Cytosol Mitochondria "HPA039230: AB_10674281" "unprognostic (1.31e-1)" "prognostic favorable (5.24e-4)" "unprognostic (6.37e-3)" "unprognostic (6.94e-2)" "unprognostic (9.19e-3)" "unprognostic (2.65e-2)" "unprognostic (2.35e-2)" "unprognostic (8.85e-2)" "unprognostic (1.79e-1)" "unprognostic (2.55e-1)" "unprognostic (4.89e-2)" "unprognostic (3.20e-1)" "unprognostic (4.08e-3)" "unprognostic (2.12e-1)" "unprognostic (2.07e-2)" "unprognostic (4.35e-1)" "unprognostic (2.99e-2)" 3.2 10.0 13.5 4.3 18.8 1.5 1.9 13.2 13.0 1.1 8.7 3.3 1.9 0.9 0.3 0.3 0.6 4.1 1.2 13.4 15.2 0.5 1024.6 6.3 0.8 30.0 27.7 0.5 1.0 0.8 1.1 2.9 16.1 1.1 2.3 3.0 2.7 0.1 0.8 0.2 2.0 0.5 10.5 1.7 2.9 0.4 19.1 0.4 1.0 0.0 0.3 3.8 0.3 11.4 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.7 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.4 0.2 0.0 0.0 0.2 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.4 0.0 0.1 0.2 0.0 0.4 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.5 1.0 0.2 0.0 0.3 0.5 0.2 0.0 0.2 0.3 0.0 0.2 0.1 0.0 0.3 0.2 0.1 0.2 0.7 0.0 0.0 0.6 0.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.5 0.1 0.1 1.1 0.0 0.4 13.5 18.8 13.2 13.0 13.4 15.2 30.0 27.7 16.1 10.5 19.1 11.4 0.2 0.0 0.6 15.0 5.1 2.4 0.4 0.0 0.0 0.2 0.4 1.5 0.5 17.2 0.0 0.0 0.0 0.8 0.3 0.1 0.0 2.8 0.0 0.1 0.2 1.3 0.0 29.5 0.1 0.4 1.3 0.6 0.0 0.1 0.0 0.1 18.9 364.6 199.4 0.0 0.1 0.0 0.0 45.1 111.9 0.0 0.0 93.7 1.8 0.0 97.6 1.9 0.0 1.0 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.5 0.0 0.3 0.6 0.0 0.0 0.4 3.1 2.5 2.4 0.8 0.0 0.1 SERPINB7 MEGSIN ENSG00000166396 "Serpin family B member 7" O75635 18 63752935-63805376 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "lymphoid tissue: 38.4;skin 1: 129.5" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 79.5;Basal respiratory cells: 353.3;Club cells: 120.7;Ductal cells: 157.8;Extravillous trophoblasts: 82.2;Pancreatic endocrine cells: 276.5" "Cancer enhanced" "Detected in many" "cervical cancer: 8.0;head and neck cancer: 8.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 240.4;fHDF/TERT166: 170.8;HaCaT: 412.8;HBEC3-KT: 131.9;HBF TERT88: 223.0;hTERT-HME1: 130.9;U-138 MG: 219.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "cerebral cortex: 12.9;hippocampal formation: 11.4" HPA024200 Enhanced Approved "Endoplasmic reticulum,Mitochondria" NA NA 160000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Endoplasmic reticulum" Mitochondria "HPA024200: AB_1856730" "unprognostic (8.66e-3)" "unprognostic (6.31e-3)" "unprognostic (6.55e-2)" "unprognostic (4.03e-4)" "unprognostic (9.11e-2)" "unprognostic (1.30e-1)" "unprognostic (1.20e-2)" "unprognostic (9.99e-2)" "unprognostic (4.70e-2)" "prognostic unfavorable (3.03e-5)" "unprognostic (2.02e-1)" "unprognostic (6.81e-2)" "unprognostic (1.62e-1)" "unprognostic (3.37e-2)" "unprognostic (2.02e-1)" "unprognostic (1.76e-3)" 0.5 0.0 0.0 0.4 0.0 0.0 13.0 0.0 0.0 3.0 0.0 0.7 0.0 0.7 0.0 1.8 0.0 0.3 0.1 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.3 0.0 0.0 0.7 0.0 0.5 129.5 0.0 0.1 0.0 0.0 0.7 0.4 0.1 4.5 0.0 0.0 38.4 0.0 4.8 0.0 28.2 0.1 0.0 0.1 0.0 3.7 0.0 240.4 48.2 36.0 26.6 0.0 1.0 0.1 0.1 170.8 62.5 412.8 0.1 131.9 223.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.4 8.6 22.9 5.5 130.9 1.8 0.0 0.0 0.0 0.8 21.7 0.0 0.0 0.0 0.6 0.0 11.9 0.0 0.5 0.0 0.2 0.1 0.0 0.0 0.2 0.1 0.1 0.8 0.1 0.2 0.0 219.4 8.1 4.7 22.8 0.1 0.0 0.0 22.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 79.5 0.9 353.3 0.0 0.0 0.1 0.0 0.0 0.0 120.7 0.0 0.0 1.9 0.0 0.5 0.0 157.8 0.1 0.0 0.0 0.5 0.0 0.0 0.2 8.8 82.2 0.5 0.0 0.3 0.0 0.0 0.0 0.0 1.9 0.0 0.3 0.0 2.0 0.0 3.0 0.0 0.0 0.2 3.6 0.0 1.6 0.0 0.0 0.5 0.3 276.5 1.1 0.0 0.0 4.5 0.0 0.3 13.0 0.0 0.0 0.0 5.4 0.0 0.2 0.0 21.9 6.2 0.1 0.0 0.0 8.2 SETD3 "C14orf154, FLJ23027" ENSG00000183576 "SET domain containing 3, actin histidine methyltransferase" Q86TU7 14 99397748-99480889 "Enzymes, Predicted intracellular proteins" "Actin-binding, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 206.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003591, HPA003639" Approved Approved Mitochondria NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "HPA003591: AB_1079930, HPA003639: AB_1079931" "unprognostic (6.82e-2)" "unprognostic (2.66e-2)" "unprognostic (8.07e-2)" "unprognostic (2.16e-2)" "unprognostic (2.42e-1)" "prognostic unfavorable (6.46e-4)" "unprognostic (1.04e-2)" "unprognostic (3.24e-2)" "unprognostic (3.29e-1)" "unprognostic (2.73e-2)" "unprognostic (2.01e-1)" "unprognostic (4.42e-1)" "prognostic favorable (1.89e-15)" "unprognostic (6.81e-2)" "unprognostic (3.21e-1)" "unprognostic (2.20e-1)" "unprognostic (2.62e-3)" 38.8 26.6 49.6 25.2 50.6 23.5 30.1 46.9 59.2 29.2 45.1 49.5 36.3 26.2 83.5 36.6 46.6 29.4 79.0 48.1 47.8 96.1 47.2 37.4 24.1 46.4 45.5 22.0 37.6 40.1 21.6 42.6 45.9 35.9 37.9 64.5 57.8 41.6 174.0 31.6 37.4 39.4 46.2 28.4 29.1 85.0 52.2 24.5 53.4 118.2 24.8 36.3 24.4 52.1 39.9 44.6 33.1 31.7 37.6 42.0 117.1 49.4 37.4 50.3 51.1 43.5 65.7 38.8 39.5 55.6 39.5 50.4 40.8 55.2 79.6 38.5 22.0 35.3 27.8 40.2 46.9 53.6 51.2 29.6 71.3 44.7 64.8 37.9 63.4 57.2 28.3 56.9 56.3 74.7 56.6 57.9 19.9 98.5 50.7 34.1 67.8 32.0 72.6 48.4 58.9 27.4 44.3 45.4 38.4 59.7 61.6 46.2 56.6 22.6 31.5 153.8 38.2 40.6 49.3 42.1 42.6 52.5 35.3 7.6 18.1 24.9 17.7 21.5 20.6 11.4 15.0 16.6 22.4 8.9 12.3 15.4 10.8 20.6 19.2 14.1 12.2 14.8 49.6 50.6 46.9 59.2 48.1 47.8 46.4 45.5 45.9 46.2 52.2 52.1 31.1 25.6 44.5 43.1 16.9 24.3 18.6 14.4 21.6 26.0 22.8 17.1 83.0 18.6 24.8 25.8 27.1 61.9 37.3 37.2 33.2 24.7 206.6 29.9 24.9 29.1 21.7 11.3 47.7 28.0 45.4 22.2 17.3 30.7 32.9 7.5 22.9 27.5 35.8 18.5 43.6 28.2 14.2 29.7 23.2 121.0 19.0 35.9 10.6 52.5 27.9 47.6 60.8 38.2 36.8 25.7 20.3 21.1 23.6 26.1 30.1 101.5 28.1 39.5 6.6 25.3 23.0 130.4 73.0 25.0 32.4 30.0 27.9 9.2 30.5 20.8 SFXN2 SLC56A2 ENSG00000156398 "Sideroflexin 2" Q96NB2 10 102714538-102743492 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 17.9;parathyroid gland: 12.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 33.3;Hepatocytes: 21.2;Proximal tubular cells: 43.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "T-47d: 38.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA018150, HPA026834" Enhanced Approved Mitochondria NA NA "Cluster 32: T-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA018150: AB_1856790, HPA026834: AB_1856791" "unprognostic (1.70e-2)" "prognostic favorable (2.28e-4)" "unprognostic (3.30e-2)" "unprognostic (2.95e-1)" "unprognostic (6.10e-2)" "unprognostic (1.44e-2)" "prognostic favorable (9.95e-4)" "unprognostic (4.24e-2)" "unprognostic (9.69e-2)" "unprognostic (3.98e-2)" "unprognostic (1.32e-1)" "unprognostic (8.98e-3)" "prognostic favorable (2.28e-5)" "unprognostic (1.20e-1)" "unprognostic (2.14e-1)" "unprognostic (3.77e-2)" "prognostic favorable (6.52e-4)" 1.5 1.1 1.2 1.9 2.8 3.0 2.8 3.9 1.7 1.6 3.6 1.9 2.5 2.7 3.6 1.4 3.6 1.1 0.6 1.8 0.8 17.9 4.2 1.6 2.6 1.0 0.5 3.4 3.1 12.7 2.7 3.4 1.2 2.2 3.0 2.7 4.9 1.3 0.7 1.9 1.9 1.1 0.2 2.1 3.3 1.2 1.8 3.2 3.8 0.2 1.9 0.9 0.7 2.1 4.2 2.3 3.5 3.7 1.3 0.9 5.1 1.4 0.6 1.8 0.9 7.2 1.9 9.1 2.7 1.2 1.0 3.0 0.7 4.8 1.0 1.6 2.8 13.1 4.4 4.5 0.6 7.5 1.1 1.0 0.7 1.8 1.8 1.1 1.7 7.7 6.0 4.2 1.1 4.0 11.5 2.5 2.3 4.0 0.8 5.5 4.3 1.3 1.7 3.5 2.6 2.5 1.2 3.1 0.6 1.4 38.4 1.6 1.2 1.4 4.4 1.8 3.1 4.6 6.5 7.9 1.7 9.0 1.2 1.6 0.5 0.2 1.9 0.2 1.7 0.8 1.9 2.0 0.7 2.5 3.0 2.5 0.9 1.9 0.3 1.7 2.0 0.7 1.2 2.8 3.9 1.7 1.8 0.8 1.0 0.5 1.2 0.2 1.8 2.1 1.0 0.0 10.1 5.2 3.8 0.9 3.0 0.8 4.0 6.1 7.3 5.2 2.5 4.3 2.0 1.8 33.3 9.1 2.4 2.5 9.8 1.9 0.8 7.3 4.2 2.2 3.6 4.2 5.4 2.8 4.4 3.2 8.2 10.0 0.0 9.2 5.0 21.2 9.6 0.0 5.5 5.0 0.0 7.5 0.6 0.5 2.1 2.4 0.0 8.4 0.8 1.1 4.1 7.1 2.9 1.4 0.8 1.5 6.7 4.4 2.4 43.1 0.4 15.1 0.0 2.7 1.7 1.2 1.3 3.3 1.3 4.5 2.8 2.6 7.3 2.9 SFXN5 "BBG-TCC, SLC56A5" ENSG00000144040 "Sideroflexin 5" Q8TD22 2 72942036-73075619 "Predicted intracellular proteins, Predicted membrane proteins" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 63.6" "Cell type enhanced" "Detected in many" "Astrocytes: 405.2;Early spermatids: 96.4;Late spermatids: 168.4" "Cancer enhanced" "Detected in all" "glioma: 13.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015473, HPA056866" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 11: Basophils - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Mitochondria" "HPA015473: AB_1856794, HPA056866: AB_2683261" "unprognostic (7.75e-2)" "unprognostic (1.64e-2)" "unprognostic (1.40e-1)" "unprognostic (2.71e-3)" "unprognostic (1.16e-1)" "unprognostic (1.48e-3)" "unprognostic (1.21e-1)" "unprognostic (1.49e-1)" "unprognostic (1.19e-1)" "unprognostic (1.22e-1)" "prognostic favorable (2.26e-6)" "unprognostic (1.57e-1)" "unprognostic (8.51e-2)" "unprognostic (3.50e-1)" "unprognostic (3.23e-1)" "unprognostic (3.97e-1)" "unprognostic (1.43e-2)" 3.2 11.7 52.1 4.6 45.5 13.7 2.5 40.0 63.6 3.2 21.9 6.1 6.9 3.1 16.6 3.1 4.2 4.0 3.5 48.0 45.2 11.4 29.4 3.6 3.9 51.5 49.2 2.6 2.4 2.0 3.5 3.7 41.4 4.2 5.7 6.2 2.2 4.5 7.7 4.5 6.5 3.9 42.6 5.6 4.6 2.4 57.0 4.9 3.7 4.6 3.0 3.8 2.3 37.4 4.2 9.1 13.7 11.5 3.0 5.0 5.4 8.4 5.4 13.3 6.9 13.7 10.7 2.3 8.8 8.9 9.2 3.7 10.8 11.1 6.0 10.2 6.7 10.7 11.0 18.7 4.4 5.9 11.1 5.8 3.5 9.0 1.1 4.9 7.4 3.2 9.5 2.9 4.3 8.7 1.5 9.5 17.1 8.1 6.6 10.6 12.2 3.1 8.1 10.5 9.0 2.7 8.6 4.3 3.5 7.7 2.2 5.3 6.8 4.1 13.5 6.1 10.2 4.0 4.1 3.1 15.0 10.3 5.3 4.7 6.0 3.5 0.6 2.6 0.9 1.6 0.3 0.7 2.7 2.4 0.4 0.5 4.6 4.3 3.2 1.9 0.7 1.7 52.1 45.5 40.0 63.6 48.0 45.2 51.5 49.2 41.4 42.6 57.0 37.4 7.1 0.0 4.4 405.2 4.8 4.7 4.3 7.6 4.6 26.8 6.9 5.5 5.8 7.2 4.8 36.8 33.3 12.4 6.8 18.4 3.9 5.1 96.4 5.1 13.1 7.6 13.8 13.7 84.4 9.1 2.4 8.9 9.2 11.2 0.0 42.8 9.3 61.3 12.4 20.2 57.4 8.6 2.0 8.7 9.6 168.4 10.5 9.6 8.8 43.1 19.7 65.8 10.3 40.2 29.9 8.0 6.5 11.3 7.1 3.6 17.5 22.2 3.2 42.3 13.1 12.2 8.8 11.2 15.7 7.3 9.2 4.2 6.3 15.9 8.8 2.3 SGIP1 DKFZp761D221 ENSG00000118473 "SH3GL interacting endocytic adaptor 1" Q9BQI5 1 66533383-66751139 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "retina: 131.4" "Group enriched" "Detected in many" 4 "Astrocytes: 390.1;Cone photoreceptor cells: 350.3;Excitatory neurons: 323.3;Inhibitory neurons: 401.5;Oligodendrocyte precursor cells: 482.0;Oligodendrocytes: 363.6;Rod photoreceptor cells: 344.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 29.9;BJ hTERT+: 38.0;fHDF/TERT166: 24.5;hTERT-RPE1: 15.8;RPTEC TERT1: 27.5;SH-SY5Y: 15.3;U-138 MG: 27.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017963 Approved Approved Mitochondria NA NA "Cluster 77: Retina - Visual perception" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 9: Photoreceptor cells - Phototransduction" Mitochondria "HPA017963: AB_10964882" "unprognostic (1.74e-2)" "unprognostic (2.77e-1)" "unprognostic (2.86e-1)" "unprognostic (1.07e-1)" "unprognostic (1.74e-1)" "unprognostic (9.04e-2)" "unprognostic (9.51e-2)" "unprognostic (7.64e-2)" "unprognostic (1.86e-1)" "unprognostic (1.61e-1)" "unprognostic (1.83e-1)" "unprognostic (1.95e-1)" "unprognostic (3.48e-7)" "unprognostic (1.77e-2)" "unprognostic (1.29e-1)" "unprognostic (4.25e-2)" "unprognostic (9.63e-2)" 7.4 4.3 12.2 1.9 15.5 0.2 2.7 6.3 17.4 10.4 0.0 3.1 1.6 10.6 4.6 2.7 3.8 4.6 5.0 15.3 5.8 18.0 0.7 8.3 0.7 5.1 5.7 1.6 0.5 0.2 7.7 1.9 5.3 5.8 1.5 131.4 1.7 5.0 2.5 1.6 2.0 3.8 1.6 0.3 3.3 4.4 5.5 0.7 8.9 1.2 0.4 2.7 5.4 10.1 0.0 0.0 0.0 0.0 0.9 5.5 0.0 29.9 38.0 2.3 3.4 0.0 0.0 0.0 0.1 24.5 0.2 0.0 0.0 0.1 4.3 0.0 0.0 1.1 0.4 0.0 6.5 0.0 0.0 4.1 0.0 2.3 0.0 15.8 11.3 0.2 0.0 0.0 13.8 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.1 27.5 0.0 0.7 15.3 0.0 0.0 0.0 0.6 0.0 1.1 1.9 27.3 0.0 0.7 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.2 15.5 6.3 17.4 15.3 5.8 5.1 5.7 5.3 1.6 5.5 10.1 5.0 0.0 0.0 390.1 0.1 1.0 0.3 0.4 0.0 89.8 0.2 4.7 2.5 2.8 0.0 9.2 350.3 0.1 0.0 0.1 7.9 0.5 0.6 2.9 7.8 13.8 0.0 0.0 323.3 0.0 0.0 15.8 0.5 5.7 10.1 0.0 0.4 0.2 0.2 74.0 401.5 0.0 0.0 0.0 1.1 1.2 2.1 0.4 10.6 48.7 0.0 49.4 0.0 482.0 363.6 0.0 0.0 11.3 0.8 0.8 0.0 0.2 0.0 344.1 13.1 3.2 32.2 0.2 0.4 0.1 1.0 0.3 0.5 0.0 0.1 0.3 SH3GL3 "CNSA3, EEN-B2, HsT19371, SH3D2C, SH3P13" ENSG00000140600 "SH3 domain containing GRB2 like 3, endophilin A3" Q99963 15 83447228-83618743 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 77.2;choroid plexus: 19.4;testis: 26.5" "Group enriched" "Detected in many" 4 "Early spermatids: 557.6;Late spermatids: 1307.0;Oligodendrocytes: 1142.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 35.8;HEK 293: 16.8;K-562: 29.9;RH-30: 11.1;SuSa: 15.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039381, HPA077877" Enhanced Approved Mitochondria NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA039381: AB_10794635, HPA077877: AB_2686863" "unprognostic (1.10e-3)" "unprognostic (6.62e-2)" "unprognostic (4.25e-2)" "unprognostic (1.86e-1)" "unprognostic (6.01e-2)" "unprognostic (2.37e-1)" "unprognostic (9.76e-2)" "unprognostic (2.26e-1)" "unprognostic (8.20e-3)" "unprognostic (2.72e-3)" "unprognostic (1.43e-6)" "unprognostic (4.42e-2)" "unprognostic (3.59e-2)" "unprognostic (2.93e-1)" "unprognostic (5.78e-4)" 0.1 0.1 43.6 0.0 53.8 0.2 0.1 35.9 72.3 0.5 19.4 0.1 0.0 0.5 0.6 1.7 2.2 0.0 0.2 43.8 46.1 0.9 0.0 2.5 0.1 42.3 47.6 0.0 0.0 0.0 0.8 0.5 46.0 0.5 0.0 4.9 0.8 0.5 0.0 0.3 0.0 0.0 40.5 0.0 0.0 26.5 43.2 9.1 0.0 0.0 0.7 0.5 0.5 77.2 0.1 0.0 3.0 2.8 0.0 0.0 2.6 0.0 0.0 0.3 0.1 0.0 0.0 0.0 1.4 0.0 0.6 0.0 35.8 2.0 0.0 0.0 16.8 6.2 0.0 0.0 0.0 0.0 0.6 0.1 0.6 0.0 0.0 0.0 0.0 8.1 29.9 0.0 0.1 0.8 2.4 0.0 4.4 0.0 1.1 0.0 11.1 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 15.2 0.0 0.0 0.4 0.0 2.9 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.6 53.8 35.9 72.3 43.8 46.1 42.3 47.6 46.0 40.5 43.2 77.2 0.1 9.6 1.7 5.9 0.0 0.9 1.4 0.5 18.2 5.4 0.1 0.4 0.6 0.0 0.3 3.7 0.0 0.9 0.0 0.0 0.0 0.6 557.6 0.1 0.1 0.9 0.0 0.0 192.6 0.0 1.7 2.6 0.0 0.1 0.0 0.2 0.4 0.0 0.4 77.4 225.2 0.0 0.0 0.0 0.0 1307.0 9.3 0.5 1.8 6.5 0.0 3.1 0.0 29.1 1142.7 0.3 0.0 4.1 0.0 0.9 0.0 0.1 3.8 1.1 0.0 0.0 0.8 29.0 8.5 9.0 0.1 0.7 0.0 17.6 0.0 0.7 SLC11A1 "LSH, NRAMP, NRAMP1" ENSG00000018280 "Solute carrier family 11 member 1" P49279 2 218382029-218396894 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Iron transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 78.6;lymphoid tissue: 46.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 108.0;Kupffer cells: 166.8;Macrophages: 209.4;monocytes: 101.2" "Cancer enhanced" "Detected in many" "glioma: 7.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "classical monocyte: 6.1;intermediate monocyte: 4.5;myeloid DC: 1.9;neutrophil: 4.1;non-classical monocyte: 6.0" "Group enriched" "Detected in many" 11 "dendritic cells: 1.9;granulocytes: 4.1;monocytes: 6.1" "Cell line enhanced" "Detected in some" "HEL: 1.2;HMC-1: 1.0" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA029590, HPA050378, HPA068540" Uncertain Approved Nucleoli,Mitochondria NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Mitochondria Nucleoli "HPA029590: AB_10794613, HPA050378: , HPA068540: " "unprognostic (2.64e-1)" "unprognostic (3.05e-2)" "unprognostic (1.46e-2)" "unprognostic (2.34e-2)" "unprognostic (1.99e-2)" "unprognostic (3.83e-2)" "unprognostic (1.04e-3)" "unprognostic (2.06e-1)" "unprognostic (1.14e-1)" "unprognostic (1.58e-2)" "unprognostic (7.29e-3)" "unprognostic (2.49e-1)" "prognostic unfavorable (2.58e-8)" "unprognostic (9.55e-2)" "unprognostic (3.50e-2)" "unprognostic (1.78e-2)" "unprognostic (1.08e-2)" 14.1 8.5 3.5 7.1 4.3 6.7 4.9 3.9 11.1 2.7 4.7 3.5 0.2 2.2 0.1 1.6 7.4 1.0 8.0 3.3 5.0 3.4 5.1 78.6 0.2 7.4 5.2 1.7 3.2 0.3 3.1 2.7 6.9 3.2 0.0 0.6 3.2 0.1 1.7 1.5 2.2 1.9 5.2 46.6 3.0 0.9 17.3 0.3 2.7 1.3 0.0 7.2 2.4 7.4 0.1 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 1.2 0.2 0.2 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.3 0.2 0.0 0.4 0.0 0.9 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.3 6.1 0.6 0.3 4.5 0.2 0.1 0.2 0.1 1.9 0.2 0.3 0.2 4.1 0.2 6.0 0.2 0.2 2.0 3.5 4.3 3.9 11.1 3.3 5.0 7.4 5.2 6.9 5.2 17.3 7.4 1.5 22.4 38.5 1.6 4.1 0.9 4.3 1.9 1.2 3.1 4.5 4.6 8.6 2.8 13.8 9.2 0.0 1.8 3.1 1.8 9.8 1.3 1.8 6.1 2.3 17.0 1.2 1.7 1.3 2.1 7.8 5.8 2.0 2.8 25.3 0.9 6.8 7.3 108.0 1.7 0.9 4.0 6.1 166.8 6.3 0.5 2.1 209.4 1.8 4.7 101.2 12.9 10.3 0.5 1.4 0.4 1.6 0.7 5.6 3.9 2.5 11.7 11.0 3.3 19.7 2.9 4.2 0.8 1.8 2.1 1.0 8.1 6.7 3.3 2.9 3.3 SLC16A12 MCT12 ENSG00000152779 "Solute carrier family 16 member 12" Q6ZSM3 10 89430299-89556641 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Symport, Transport" Cataract "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "choroid plexus: 92.2;epididymis: 51.8;kidney: 85.2;pancreas: 25.3" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 18.1;Leydig cells: 27.1;Peritubular cells: 26.7;Proximal tubular cells: 69.2" "Cancer enriched" "Detected in many" 10 "renal cancer: 18.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC TERT1: 23.0;HSkMC: 8.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037587 Approved Mitochondria NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA037587: AB_2732475" "unprognostic (5.38e-2)" "unprognostic (1.29e-1)" "unprognostic (2.79e-2)" "unprognostic (2.28e-2)" "unprognostic (3.51e-1)" "unprognostic (5.35e-2)" "unprognostic (2.45e-1)" "unprognostic (1.32e-1)" "unprognostic (1.78e-2)" "unprognostic (2.42e-1)" "unprognostic (9.60e-2)" "unprognostic (2.31e-1)" "prognostic favorable (4.50e-12)" "unprognostic (3.84e-2)" "unprognostic (7.91e-2)" "unprognostic (8.29e-2)" "unprognostic (1.84e-3)" 1.8 2.5 0.8 0.1 1.1 0.0 1.9 1.0 2.7 9.2 92.2 0.8 0.1 1.4 51.8 0.3 4.1 0.1 4.9 2.9 0.3 85.2 2.0 2.5 0.1 0.5 1.6 1.3 25.3 0.1 3.4 11.6 0.6 0.6 0.2 0.0 0.4 14.1 1.6 0.5 0.3 0.3 1.2 0.0 1.0 3.3 1.0 0.4 6.2 2.5 0.0 0.4 0.7 0.6 0.2 0.0 0.0 0.0 3.0 23.0 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.1 0.0 1.2 0.2 0.0 0.3 0.5 0.0 0.0 0.0 0.5 0.0 3.7 0.0 0.0 8.2 0.2 1.2 1.5 2.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.0 2.8 0.0 0.1 0.1 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 1.1 1.0 2.7 2.9 0.3 0.5 1.6 0.6 1.2 1.0 0.6 0.8 3.2 3.9 3.3 0.6 0.0 2.2 0.1 0.0 0.1 4.6 0.1 3.3 1.5 2.9 14.7 0.0 16.4 0.1 0.0 15.6 0.0 8.3 11.5 0.8 1.3 18.1 0.0 0.3 4.1 1.1 2.2 0.0 1.0 1.3 0.0 0.4 2.2 1.2 3.3 0.4 0.2 0.0 0.0 0.9 4.8 27.1 1.0 0.0 11.2 0.1 0.0 0.0 0.0 0.4 2.1 0.1 26.7 0.0 0.7 0.0 69.2 6.2 0.6 13.1 3.4 7.8 0.2 0.5 0.0 0.3 9.0 0.9 0.1 0.0 1.8 SLC22A4 "DFNB60, MGC34546, OCTN1" ENSG00000197208 "Solute carrier family 22 member 4" Q9H015 5 132294394-132344190 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Ion transport, Sodium transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.7" "Group enriched" "Detected in many" 5 "Erythroid cells: 57.0;Proximal enterocytes: 25.6;Respiratory ciliated cells: 78.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "neutrophil: 36.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 36.2" "Cell line enhanced" "Detected in many" "BJ hTERT+: 59.1;U-138 MG: 24.4" "Region enhanced" "Detected in all" "cerebellum: 64.5" "Low region specificity" "Detected in all" "CAB015468, HPA036974" Approved Approved Mitochondria NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" Mitochondria "CAB015468: , HPA036974: AB_2732474" "unprognostic (1.33e-1)" "unprognostic (2.20e-1)" "unprognostic (3.91e-2)" "unprognostic (8.42e-3)" "unprognostic (6.17e-2)" "unprognostic (6.22e-3)" "unprognostic (4.17e-3)" "unprognostic (3.33e-1)" "unprognostic (1.30e-1)" "unprognostic (9.79e-2)" "unprognostic (1.95e-3)" "unprognostic (7.82e-2)" "unprognostic (1.74e-2)" "unprognostic (2.31e-3)" "unprognostic (1.20e-1)" "unprognostic (1.95e-2)" "unprognostic (4.06e-2)" 1.9 3.0 2.1 2.9 1.9 20.7 2.2 3.7 1.8 1.5 1.1 2.0 3.5 1.4 1.4 0.4 11.3 1.9 1.9 1.9 3.6 7.1 0.8 2.9 0.3 4.0 3.7 2.1 0.6 2.6 2.6 1.0 3.4 4.0 2.2 2.2 1.7 1.4 7.2 1.3 9.1 1.0 3.6 5.1 1.4 0.6 3.4 0.4 0.7 2.7 0.2 1.4 0.9 2.9 1.9 3.0 0.2 0.7 1.3 1.0 0.9 12.9 59.1 9.7 10.1 1.1 3.3 0.6 3.6 7.6 7.2 3.2 0.0 2.1 6.8 2.6 0.3 0.1 5.6 0.2 1.0 4.1 0.0 2.3 0.4 5.3 4.9 3.5 4.3 0.3 5.3 6.7 7.6 1.1 0.0 9.5 0.3 0.3 3.2 0.0 0.8 0.4 1.5 0.2 0.8 0.4 14.0 0.9 0.4 0.4 0.6 2.4 5.2 24.4 2.4 9.7 3.3 0.0 2.7 0.0 7.2 4.7 2.9 0.0 5.6 5.8 0.0 1.3 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 36.2 0.0 0.4 0.3 0.0 1.2 2.1 1.9 3.7 1.8 1.9 3.6 4.0 3.7 3.4 3.6 3.4 2.9 1.1 3.2 0.0 5.5 0.1 0.8 1.0 3.8 1.8 2.0 1.9 1.3 0.8 1.5 10.0 0.0 0.0 1.0 0.1 8.8 0.0 3.2 0.0 4.7 1.8 3.8 1.2 57.0 7.2 0.4 2.3 3.1 0.5 2.2 0.0 0.6 1.4 0.0 4.0 3.3 8.0 0.8 4.1 0.8 0.8 0.3 0.6 3.7 0.0 1.9 2.2 1.6 0.0 4.5 2.3 1.9 1.7 0.0 0.1 1.7 25.6 8.6 78.5 0.4 0.0 9.3 1.8 0.3 0.4 0.2 0.4 2.5 0.2 0.1 1.0 0.9 SLC22A5 "CDSP, OCTN2, SCD" ENSG00000197375 "Solute carrier family 22 member 5" O76082 5 132369710-132395613 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 56.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 63.9;Proximal enterocytes: 56.2" "Cancer enhanced" "Detected in all" "renal cancer: 8.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HeLa: 34.7;SiHa: 37.8" "Low region specificity" "Detected in some" HPA063062 Approved Mitochondria NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA063062: AB_2684934" "unprognostic (3.88e-1)" "unprognostic (1.69e-1)" "unprognostic (2.19e-2)" "prognostic favorable (2.87e-5)" "unprognostic (5.37e-3)" "unprognostic (1.18e-1)" "unprognostic (1.50e-2)" "unprognostic (9.24e-2)" "unprognostic (1.57e-1)" "unprognostic (5.09e-2)" "prognostic favorable (7.36e-4)" "unprognostic (3.53e-2)" "prognostic favorable (8.36e-4)" "unprognostic (1.12e-2)" "unprognostic (2.98e-2)" "unprognostic (2.17e-2)" "unprognostic (1.17e-2)" 5.3 6.6 7.5 2.0 7.9 0.9 4.9 7.8 7.8 5.0 14.4 12.4 13.7 4.0 11.1 3.9 8.4 4.1 14.2 7.3 8.0 26.7 7.8 3.2 1.2 7.8 7.8 5.6 8.2 17.9 11.0 4.2 7.4 9.1 9.4 3.7 6.4 11.2 56.1 6.0 16.9 2.5 7.5 2.5 6.0 3.8 8.0 2.1 5.4 22.3 1.8 5.0 5.0 7.8 6.1 14.4 0.9 11.3 4.4 2.1 19.3 2.7 2.9 4.5 6.2 10.7 12.2 2.9 6.0 2.6 13.1 14.3 9.4 7.0 5.3 3.6 11.6 1.5 34.7 4.9 7.3 2.4 2.4 2.0 12.9 3.1 15.8 7.6 1.2 5.2 6.8 1.8 4.4 10.4 3.6 2.4 1.0 10.5 6.2 1.3 0.0 15.9 13.5 15.2 4.8 3.3 37.8 28.9 7.6 2.9 13.5 3.1 0.7 0.7 3.9 9.5 3.3 6.0 12.8 0.1 2.9 5.9 2.7 0.0 2.0 0.0 1.1 1.0 1.2 0.6 1.1 1.4 3.1 0.6 1.1 1.4 0.2 0.8 0.3 0.2 2.1 1.0 7.5 7.9 7.8 7.8 7.3 8.0 7.8 7.8 7.4 7.5 8.0 7.8 3.0 9.6 8.2 23.5 3.8 7.6 7.5 4.7 13.1 6.7 16.9 5.3 5.6 21.5 5.5 16.5 12.5 23.6 3.2 63.9 1.9 9.8 2.0 13.7 10.3 2.6 7.2 1.7 11.9 5.2 5.5 5.6 16.3 26.6 0.0 6.1 2.9 8.6 4.2 10.1 11.1 14.3 8.2 6.7 1.6 2.8 6.5 5.9 5.4 17.8 1.3 9.4 0.0 7.1 4.2 6.4 26.3 4.1 4.8 14.2 56.2 22.2 9.4 7.1 0.0 17.7 3.8 8.4 2.8 9.6 6.3 8.2 4.0 0.3 18.0 9.0 SLC25A14 "BMCP1, UCP5" ENSG00000102078 "Solute carrier family 25 member 14" O95258 X 130339888-130373361 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Respiratory ciliated cells: 34.2;Spermatogonia: 37.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060316 Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 16: U-266 - Nucleosome" "Cluster 49: Ciliated cells - Cilium organization" Mitochondria "HPA060316: AB_2684251" "unprognostic (1.65e-2)" "prognostic favorable (1.72e-5)" "unprognostic (1.82e-1)" "unprognostic (2.74e-1)" "unprognostic (1.27e-1)" "unprognostic (1.16e-1)" "unprognostic (3.36e-3)" "unprognostic (8.92e-3)" "unprognostic (3.52e-2)" "unprognostic (2.95e-3)" "prognostic favorable (1.78e-4)" "unprognostic (2.18e-2)" "prognostic unfavorable (5.52e-6)" "unprognostic (6.05e-2)" "unprognostic (1.12e-1)" "unprognostic (6.92e-2)" "prognostic favorable (1.39e-5)" 2.5 5.6 10.7 2.1 11.5 2.7 3.3 8.2 12.6 3.3 7.3 3.6 1.3 4.1 6.5 2.6 5.9 2.6 4.7 11.4 14.3 3.2 2.5 2.8 2.8 8.7 9.0 4.0 3.4 4.2 10.8 2.2 9.8 3.0 2.4 10.2 3.2 3.7 3.7 2.9 2.4 4.5 8.2 2.3 3.0 6.6 11.5 3.9 3.4 2.3 3.3 2.6 2.5 8.8 9.0 11.7 8.1 6.1 5.4 5.0 4.4 6.6 8.7 12.3 12.6 4.7 5.3 6.1 22.6 9.0 14.7 4.9 11.9 5.0 12.2 7.6 15.0 2.0 10.7 11.1 7.8 7.7 3.5 4.7 5.9 15.8 4.8 7.4 7.1 8.4 4.9 8.5 20.2 13.8 8.2 10.8 6.7 9.7 18.4 6.9 10.6 12.2 7.5 3.8 10.4 9.2 7.0 7.0 11.7 5.3 4.5 4.3 4.8 6.8 4.5 15.6 13.6 7.8 21.0 5.0 12.3 9.3 6.2 3.2 3.4 2.6 3.0 2.8 3.6 3.9 2.4 2.8 3.7 2.0 1.9 3.1 4.1 3.8 2.7 4.5 4.7 2.4 10.7 11.5 8.2 12.6 11.4 14.3 8.7 9.0 9.8 8.2 11.5 8.8 4.5 6.4 2.2 5.9 5.6 9.9 8.3 13.3 7.4 10.0 6.6 6.1 4.1 8.6 5.3 3.7 2.1 9.1 4.3 4.5 17.6 10.2 15.8 16.0 5.5 5.1 9.0 3.4 12.7 9.1 8.2 5.4 5.6 4.2 3.8 9.7 7.5 4.3 5.2 6.7 11.9 3.8 12.2 4.7 4.1 7.7 5.0 4.9 8.8 5.6 4.5 8.2 3.1 4.5 5.3 9.0 4.2 8.2 9.0 4.2 4.7 10.7 34.2 13.6 6.6 5.3 9.2 29.1 37.3 7.3 8.4 5.3 5.8 6.5 4.5 6.5 SLC25A16 "D10S105E, GDA, HGT.1, ML7" ENSG00000122912 "Solute carrier family 25 member 16" P16260 10 68477998-68527523 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036243, HPA044580" Uncertain Approved Mitochondria NA NA "Cluster 17: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA036243: AB_2675019, HPA044580: AB_10962723" "unprognostic (1.71e-1)" "unprognostic (1.54e-1)" "unprognostic (3.08e-2)" "unprognostic (1.27e-1)" "unprognostic (6.75e-2)" "unprognostic (2.68e-2)" "unprognostic (1.23e-2)" "unprognostic (9.13e-3)" "unprognostic (1.92e-1)" "unprognostic (4.13e-2)" "unprognostic (8.65e-2)" "unprognostic (1.17e-1)" "unprognostic (8.37e-3)" "unprognostic (2.10e-1)" "unprognostic (2.79e-1)" "unprognostic (2.06e-2)" "unprognostic (1.44e-3)" 10.3 3.6 5.1 2.1 5.3 3.7 4.1 7.1 7.9 2.1 0.0 3.2 3.8 3.5 3.2 2.6 2.1 2.3 2.8 5.0 5.6 5.8 11.4 3.1 2.7 2.7 3.5 2.3 5.1 3.5 2.6 2.8 3.4 8.2 2.8 4.7 4.5 2.8 4.9 3.0 3.8 2.6 2.2 2.4 4.5 1.5 7.0 2.0 3.5 2.3 2.0 2.7 2.1 6.1 2.8 1.1 3.2 4.4 4.2 5.0 3.4 3.8 4.2 2.4 2.6 6.6 1.9 3.0 2.7 7.6 1.3 1.6 10.2 1.9 6.1 2.2 6.3 1.6 3.5 2.9 5.1 5.2 3.4 4.3 4.9 4.6 6.4 3.6 2.0 2.6 1.8 4.8 5.2 2.6 2.9 3.7 0.7 0.8 14.8 1.6 2.3 1.0 6.8 9.2 2.2 1.8 5.4 5.2 4.4 2.2 2.9 2.1 8.9 3.6 4.8 6.1 4.5 4.9 2.8 4.9 3.5 4.2 1.6 1.4 0.7 0.7 0.4 0.5 0.4 0.4 0.4 0.3 0.5 0.8 0.4 0.6 1.3 0.6 0.4 0.8 0.4 0.3 5.1 5.3 7.1 7.9 5.0 5.6 2.7 3.5 3.4 2.2 7.0 6.1 9.6 44.8 20.7 23.5 9.9 6.4 6.3 4.9 4.6 19.2 11.0 6.7 10.4 12.8 7.4 12.9 39.6 19.0 12.4 12.9 11.7 8.1 9.9 9.6 9.3 7.8 15.0 9.9 44.0 19.2 32.3 8.8 20.9 14.1 8.2 6.1 13.9 37.7 10.6 20.2 53.7 9.4 8.2 10.3 6.5 13.0 3.1 7.9 1.8 13.1 8.2 9.5 15.5 29.7 48.0 14.4 7.8 7.9 16.4 13.5 17.7 21.4 9.9 31.2 0.0 13.4 11.3 4.5 2.5 10.5 6.8 59.8 9.4 9.4 9.0 10.6 SLC25A18 ENSG00000182902 "Solute carrier family 25 member 18" Q9H1K4 22 17563450-17590995 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 143.8;choroid plexus: 90.7;liver: 111.5" "Group enriched" "Detected in many" 4 "Astrocytes: 195.2;Hepatocytes: 72.8" "Group enriched" "Detected in some" 5 "glioma: 10.6;liver cancer: 11.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 3.8;BEWO: 8.5" "Low region specificity" "Detected in all" HPA068110 Approved Nucleoplasm,Mitochondria NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 28: BEWO - Transcription regulation" "Cluster 64: Astrocytes - Nervous system maintenance" Mitochondria Nucleoplasm "HPA068110: " "unprognostic (2.15e-1)" "unprognostic (6.07e-2)" "unprognostic (4.95e-2)" "unprognostic (1.01e-1)" "unprognostic (3.79e-1)" "unprognostic (3.98e-2)" "unprognostic (1.00e-1)" "unprognostic (1.89e-1)" "unprognostic (1.45e-2)" "unprognostic (2.72e-2)" "unprognostic (8.70e-4)" "unprognostic (1.44e-1)" "unprognostic (3.92e-2)" "unprognostic (1.67e-2)" "unprognostic (1.29e-1)" "unprognostic (5.24e-2)" "unprognostic (1.62e-1)" 14.4 1.0 130.1 0.3 132.1 0.1 7.2 116.5 141.1 2.5 90.7 2.9 0.3 2.9 0.2 0.3 3.8 0.9 2.8 119.4 123.3 1.9 111.5 1.2 0.3 121.7 129.2 1.2 1.1 0.2 1.5 0.1 112.5 7.8 0.1 1.9 0.5 0.4 6.2 1.2 1.9 0.5 106.5 4.8 1.5 4.2 143.8 0.3 0.6 4.0 0.1 0.8 1.4 110.7 0.3 0.6 2.2 0.4 3.8 0.0 8.5 0.3 0.0 0.0 0.0 0.2 0.2 0.2 0.2 0.0 2.5 0.7 0.0 0.0 0.0 0.3 1.0 0.3 0.3 0.5 1.5 0.3 0.4 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.4 0.3 0.0 0.4 0.1 0.5 2.0 0.9 1.4 2.9 0.8 0.0 0.1 0.4 0.8 0.3 0.2 0.4 0.7 1.6 2.5 1.0 0.1 0.1 0.3 0.2 0.3 0.9 1.2 0.0 1.8 0.2 0.4 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 130.1 132.1 116.5 141.1 119.4 123.3 121.7 129.2 112.5 106.5 143.8 110.7 1.0 28.9 10.3 195.2 0.3 0.0 0.3 0.1 0.6 0.6 0.3 0.0 1.5 5.7 7.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.6 0.4 0.9 1.7 0.0 10.7 2.0 0.0 0.3 4.7 0.0 0.7 6.3 8.5 3.6 72.8 0.3 0.0 3.0 0.3 0.0 4.1 0.3 0.6 0.9 3.9 0.0 10.3 0.1 2.2 1.0 13.0 11.5 0.0 0.0 2.6 0.1 4.3 0.1 0.8 15.8 3.4 0.0 2.7 2.5 4.8 5.9 0.0 0.1 1.8 2.6 2.6 0.0 0.2 SLC25A32 MFTC ENSG00000164933 "Solute carrier family 25 member 32" Q9H2D1 8 103398635-103415189 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA024763, HPA047402" Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" Mitochondria Nucleoplasm "HPA024763: , HPA047402: AB_2680032" "unprognostic (2.45e-3)" "unprognostic (8.19e-2)" "unprognostic (3.87e-3)" "prognostic unfavorable (7.23e-4)" "unprognostic (2.06e-2)" "unprognostic (6.50e-3)" "unprognostic (1.22e-2)" "prognostic unfavorable (2.09e-4)" "unprognostic (9.47e-2)" "unprognostic (8.43e-2)" "unprognostic (2.08e-1)" "unprognostic (9.21e-2)" "prognostic unfavorable (1.53e-6)" "unprognostic (7.82e-2)" "unprognostic (2.12e-1)" "unprognostic (1.62e-1)" "unprognostic (4.49e-2)" 13.5 7.2 3.1 12.5 3.9 14.6 11.2 4.1 4.8 8.6 2.9 7.7 6.8 10.7 7.5 7.3 9.3 11.5 9.7 4.1 4.5 9.6 17.9 8.5 16.9 4.7 4.6 9.6 8.5 8.8 11.3 10.1 4.6 8.0 7.7 1.4 6.4 7.5 9.6 6.9 7.6 10.9 4.6 12.7 7.0 6.4 4.0 8.7 7.1 9.2 12.8 15.0 7.0 5.3 33.7 11.5 10.5 18.3 21.3 23.3 10.3 27.4 39.9 30.6 31.4 14.0 19.6 73.8 25.8 29.5 17.7 20.4 22.5 22.5 47.0 45.5 16.1 53.5 8.5 18.3 37.4 26.5 23.1 23.1 17.9 34.5 51.2 8.6 32.5 19.4 33.9 25.9 30.5 13.5 45.0 21.6 17.1 39.3 23.6 33.6 16.3 50.8 20.8 12.7 28.0 17.2 13.6 22.3 48.9 10.5 19.3 18.5 22.6 36.7 24.9 44.2 36.2 19.2 19.7 76.8 31.0 38.1 27.5 0.6 3.3 1.6 6.0 3.7 7.3 7.0 6.4 6.9 4.1 4.8 6.5 6.7 0.8 5.2 4.3 3.5 5.5 5.7 3.1 3.9 4.1 4.8 4.1 4.5 4.7 4.6 4.6 4.6 4.0 5.3 28.9 3.2 3.3 10.1 46.9 23.1 16.7 6.9 32.5 9.4 10.3 6.7 10.4 11.5 5.4 5.5 6.2 11.9 20.9 4.1 7.9 9.8 4.8 8.3 14.0 22.2 11.4 16.2 30.3 9.4 13.6 19.6 27.0 9.1 8.9 8.0 20.0 15.2 10.2 8.4 25.8 7.1 8.2 7.3 11.6 4.7 9.3 16.2 10.6 24.4 9.9 7.6 15.5 25.6 46.6 10.0 3.1 8.6 56.3 14.4 4.1 9.5 2.6 8.1 19.7 13.5 14.7 22.9 17.1 32.6 25.9 14.0 27.7 9.5 7.5 15.1 SLC25A34 DKFZp781A10161 ENSG00000162461 "Solute carrier family 25 member 34" Q6PIV7 1 15736258-15741392 "Predicted membrane proteins, Transporters" Transport "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "heart muscle: 14.4;intestine: 14.0;skeletal muscle: 37.8;tongue: 47.3" "Cell type enriched" "Detected in many" 5 "Proximal enterocytes: 44.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "SK-MEL-30: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069806 Approved Mitochondria NA NA "Cluster 32: T-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 45: Enterocytes - Digestion" Mitochondria "HPA069806: AB_2686202" "unprognostic (2.06e-1)" "unprognostic (4.72e-1)" "unprognostic (1.15e-1)" "unprognostic (2.43e-1)" "unprognostic (2.58e-1)" "unprognostic (8.08e-3)" "unprognostic (1.98e-2)" "unprognostic (9.92e-2)" "unprognostic (1.55e-1)" "unprognostic (1.55e-1)" "unprognostic (1.80e-4)" "unprognostic (5.74e-2)" "unprognostic (6.10e-2)" "unprognostic (4.02e-1)" "unprognostic (1.82e-1)" "unprognostic (4.04e-2)" "unprognostic (2.40e-4)" 2.4 4.4 3.7 1.0 3.8 3.4 1.8 6.8 4.8 3.6 2.4 5.7 14.0 3.1 0.8 1.7 2.9 1.5 14.4 3.6 3.4 4.7 5.6 2.4 1.2 3.2 3.1 4.2 4.9 0.6 3.8 1.3 3.5 2.4 2.0 1.9 4.7 0.8 37.8 1.8 13.7 1.1 2.7 3.7 2.2 2.5 3.7 0.5 3.4 47.3 0.5 2.8 2.3 3.6 0.3 0.2 1.5 0.6 0.7 0.3 0.6 0.2 0.1 0.3 0.2 0.6 0.8 0.4 0.3 0.3 0.8 0.3 0.2 0.2 0.3 0.5 0.3 0.7 0.5 0.2 0.2 0.2 0.9 0.3 1.1 0.4 0.1 0.9 0.2 2.0 0.3 1.3 0.2 0.7 1.7 0.9 1.3 0.2 0.4 0.9 1.3 0.4 0.1 0.0 0.3 1.2 0.3 0.4 3.4 1.4 0.7 1.0 0.8 0.7 1.0 1.0 0.2 1.7 1.6 0.3 0.2 0.9 0.6 0.5 0.1 0.1 0.4 0.0 0.9 0.1 0.9 0.6 0.0 0.2 1.2 0.7 0.6 0.6 0.0 0.1 0.4 0.3 3.7 3.8 6.8 4.8 3.6 3.4 3.2 3.1 3.5 2.7 3.7 3.6 0.9 0.0 0.0 6.2 0.4 0.3 0.3 0.6 0.0 2.6 0.5 0.5 2.7 1.5 0.2 0.0 0.0 0.3 0.3 8.8 0.0 0.2 0.3 0.4 1.3 1.2 3.5 0.0 5.1 0.2 0.4 0.8 2.0 1.7 0.0 1.3 2.2 2.3 1.5 3.3 4.6 3.1 0.0 1.9 0.3 1.0 0.9 1.5 0.0 2.8 1.1 1.8 0.0 2.5 1.7 0.3 8.0 0.4 0.0 0.6 44.6 3.7 0.0 1.8 0.0 2.7 0.9 0.6 0.6 1.1 0.1 1.4 0.6 0.4 5.5 0.7 SLC25A35 FLJ40217 ENSG00000125434 "Solute carrier family 25 member 35" Q3KQZ1 17 8287763-8295400 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 20.9;Syncytiotrophoblasts: 17.4" "Cancer enhanced" "Detected in all" "endometrial cancer: 14.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051720 Uncertain Approved Vesicles,Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 71: Testis - DNA repair" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" "Vesicles, Mitochondria" "HPA051720: AB_2681584" "unprognostic (4.73e-2)" "unprognostic (1.36e-3)" "unprognostic (1.21e-2)" "prognostic favorable (3.37e-7)" "unprognostic (1.61e-2)" "unprognostic (1.20e-1)" "unprognostic (3.52e-2)" "unprognostic (5.27e-2)" "unprognostic (2.58e-1)" "unprognostic (8.30e-2)" "unprognostic (8.96e-3)" "unprognostic (1.18e-1)" "prognostic favorable (1.14e-6)" "unprognostic (5.31e-3)" "unprognostic (2.34e-1)" "unprognostic (1.00e-1)" "prognostic favorable (1.91e-5)" 5.7 8.3 2.9 4.9 3.9 6.1 8.6 3.5 4.4 10.0 4.6 7.7 6.1 13.4 7.6 5.4 7.1 5.2 4.8 2.9 3.2 15.0 4.6 6.8 5.0 3.9 4.0 2.9 12.2 6.1 12.8 4.1 4.1 8.7 5.3 4.5 6.4 5.2 2.2 4.5 7.7 4.1 3.3 8.9 12.5 24.5 4.4 5.2 9.1 1.5 3.5 6.0 5.0 4.2 5.0 13.5 2.4 10.0 7.5 2.9 5.5 3.2 2.8 3.4 3.7 1.6 12.4 5.8 3.3 3.7 7.1 11.0 2.8 3.8 1.9 3.2 3.6 4.8 11.1 1.9 2.7 0.7 12.8 5.9 2.1 6.5 1.2 2.5 5.4 6.8 1.4 2.0 2.9 2.7 5.3 2.7 0.8 3.4 4.4 5.8 1.6 2.6 2.6 12.6 1.2 3.0 9.2 5.4 4.1 2.4 12.2 3.6 7.6 2.3 1.7 5.6 2.7 4.3 2.9 2.1 5.9 8.6 6.1 4.1 5.6 7.6 4.0 8.8 3.3 1.9 3.7 4.3 5.7 3.6 1.3 2.5 1.1 2.8 6.5 3.0 4.1 2.5 2.9 3.9 3.5 4.4 2.9 3.2 3.9 4.0 4.1 3.3 4.4 4.2 3.1 0.0 5.4 5.2 3.6 0.8 1.5 1.4 2.8 4.3 6.3 4.1 1.0 5.7 1.8 11.0 8.4 9.2 2.1 3.8 11.7 2.8 3.8 10.2 1.9 2.8 9.0 4.6 0.5 7.1 2.3 3.0 5.1 10.6 5.1 1.3 1.8 2.8 6.7 1.7 0.7 3.0 2.0 6.4 1.5 5.5 1.5 4.2 0.0 4.7 5.8 7.9 3.1 1.0 2.5 3.2 6.0 1.2 3.7 1.9 2.4 7.3 2.0 9.0 0.0 1.1 1.2 20.9 0.8 1.9 0.3 17.4 3.2 9.1 3.1 1.9 SLC25A36 "FLJ10618, PNC2" ENSG00000114120 "Solute carrier family 25 member 36" Q96CQ1 3 140941830-140980995 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027036 Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 52: Non-specific - Ribosome" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 52: Non-specific - Transcription" "Mitochondria, Cytosol" Nucleoplasm "HPA027036: AB_1857048" "unprognostic (4.12e-2)" "unprognostic (9.98e-2)" "unprognostic (2.86e-1)" "unprognostic (1.37e-1)" "unprognostic (6.52e-2)" "unprognostic (3.46e-1)" "unprognostic (9.00e-2)" "unprognostic (1.71e-2)" "unprognostic (1.99e-2)" "unprognostic (2.47e-2)" "unprognostic (3.82e-1)" "unprognostic (2.10e-2)" "unprognostic (2.33e-1)" "unprognostic (1.20e-1)" "unprognostic (2.34e-1)" "unprognostic (6.03e-2)" "prognostic favorable (1.55e-4)" 27.1 22.2 16.6 14.3 16.2 61.6 33.5 16.2 22.7 31.9 13.9 25.7 30.9 34.4 47.7 15.0 32.6 18.4 39.8 16.1 20.1 38.7 4.2 27.5 21.3 17.0 16.4 39.0 45.2 28.9 26.9 26.4 17.5 27.1 19.5 42.6 23.4 20.8 38.4 22.5 22.9 19.2 16.9 20.1 34.0 23.8 18.2 20.6 31.8 20.8 17.6 23.0 23.9 21.5 52.3 11.5 36.0 30.8 33.0 40.7 46.2 19.4 23.6 18.2 27.3 28.6 24.0 42.1 46.9 17.3 31.2 34.9 40.1 15.2 40.6 33.8 36.5 33.9 29.8 20.9 45.9 48.8 21.3 44.1 61.1 15.4 45.8 44.4 22.0 32.0 17.6 27.4 29.2 22.8 30.6 34.1 37.8 12.8 18.4 34.2 32.0 59.6 23.5 17.7 22.4 38.2 26.7 45.1 80.9 30.3 32.6 29.2 24.1 29.5 17.1 52.2 19.0 56.4 36.8 51.2 36.0 21.1 15.0 10.7 9.2 15.1 9.6 11.5 11.8 16.3 9.6 10.2 14.0 15.1 13.5 12.6 1.7 18.3 13.5 9.7 9.9 9.8 16.6 16.2 16.2 22.7 16.1 20.1 17.0 16.4 17.5 16.9 18.2 21.5 60.3 99.3 143.0 85.5 47.6 68.2 68.0 38.1 116.7 106.0 72.2 77.5 90.3 38.6 52.0 71.7 133.5 58.8 58.2 22.7 64.6 26.4 10.6 113.4 78.0 45.8 59.3 27.3 127.7 38.3 38.0 73.9 58.1 106.3 65.9 92.8 35.7 0.5 26.5 92.5 115.6 32.5 30.5 38.2 45.8 16.0 59.7 38.4 56.9 46.9 36.9 68.2 25.7 108.6 109.1 29.3 22.8 59.5 48.2 88.9 44.9 57.5 98.8 121.8 59.2 80.0 59.2 59.4 68.8 61.3 54.4 49.4 49.1 83.2 46.8 78.9 SLC25A37 "HT015, MFRN, MFRN1, MSCP" ENSG00000147454 "Solute carrier family 25 member 37" Q9NYZ2 8 23528956-23575463 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Ion transport, Iron transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 138.4" "Cell type enhanced" "Detected in all" "Early spermatids: 707.8;Erythroid cells: 4197.2;Late spermatids: 1087.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 19 "neutrophil: 57.7" "Lineage enriched" "Detected in all" 19 "granulocytes: 57.7" "Cell line enhanced" "Detected in all" "HEL: 118.7;hTERT-RPE1: 65.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045680 Uncertain Approved Mitochondria,Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" Mitochondria Cytosol "HPA045680: AB_10963693" "unprognostic (6.15e-3)" "unprognostic (7.33e-3)" "unprognostic (2.04e-1)" "unprognostic (1.40e-1)" "unprognostic (1.38e-1)" "unprognostic (5.12e-2)" "unprognostic (1.35e-1)" "unprognostic (1.68e-1)" "unprognostic (3.58e-2)" "unprognostic (1.40e-1)" "unprognostic (1.02e-2)" "unprognostic (2.24e-1)" "prognostic unfavorable (4.37e-6)" "unprognostic (8.27e-2)" "unprognostic (1.71e-1)" "unprognostic (2.37e-1)" "unprognostic (7.40e-2)" 14.5 41.9 13.5 16.5 16.9 138.4 17.9 13.4 21.0 26.8 15.2 11.4 50.6 9.8 6.0 9.9 17.2 6.7 15.3 13.4 14.0 20.1 25.2 26.4 6.0 15.0 14.1 23.0 29.5 10.9 15.0 8.0 15.4 35.5 5.7 10.3 36.7 7.5 16.2 10.1 21.8 5.7 13.0 46.1 11.1 6.8 15.0 2.8 14.6 12.7 5.0 13.4 20.4 14.6 9.6 10.3 10.7 9.9 13.7 16.8 15.7 7.4 9.6 5.3 5.9 10.4 19.9 15.3 8.7 6.3 34.5 12.0 9.9 20.0 7.2 2.3 4.9 118.7 19.4 3.7 11.5 6.7 4.4 14.5 19.2 11.6 11.5 65.9 8.4 12.3 26.3 7.5 8.5 4.2 8.1 28.1 5.4 11.6 7.5 8.3 5.3 6.0 16.4 5.2 3.2 4.6 10.1 15.2 7.6 10.0 4.4 10.3 13.3 25.6 3.8 15.3 14.5 5.9 2.4 9.4 24.1 16.1 16.5 1.4 3.0 2.7 1.1 1.1 0.9 2.3 0.6 0.5 2.8 1.5 2.1 1.2 57.7 1.3 1.5 0.6 1.3 1.4 13.5 16.9 13.4 21.0 13.4 14.0 15.0 14.1 15.4 13.0 15.0 14.6 43.5 38.5 61.7 36.6 45.5 93.3 125.2 95.8 28.5 35.6 120.0 49.1 35.6 61.5 75.8 77.3 68.8 44.6 19.1 78.4 15.6 93.8 707.8 33.1 68.6 94.5 20.4 4197.2 44.0 226.4 76.4 95.4 43.8 50.0 36.8 49.7 151.3 38.8 41.7 6.7 37.3 44.7 36.7 59.0 141.2 1087.9 52.5 86.8 69.4 73.1 45.5 30.5 10.3 16.1 21.9 176.9 47.7 37.2 24.0 347.1 189.0 34.1 42.5 59.7 19.7 55.9 52.3 24.6 42.3 23.3 53.8 18.3 32.4 86.7 70.3 137.6 SLC25A44 "FLJ90431, KIAA0446" ENSG00000160785 "Solute carrier family 25 member 44" Q96H78 1 156193932-156212796 "Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 114.1;Late spermatids: 95.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 70.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065411 Approved Nucleoplasm,Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 29: Early spermatids - Spermatogenesis" Mitochondria Nucleoplasm "HPA065411: AB_2685486" "unprognostic (1.58e-1)" "unprognostic (1.78e-1)" "unprognostic (4.62e-1)" "unprognostic (2.44e-3)" "unprognostic (2.75e-1)" "unprognostic (1.32e-1)" "unprognostic (5.72e-2)" "unprognostic (8.92e-2)" "unprognostic (1.97e-1)" "unprognostic (3.58e-1)" "prognostic favorable (2.49e-4)" "unprognostic (3.37e-2)" "unprognostic (2.55e-2)" "unprognostic (2.71e-1)" "unprognostic (2.67e-1)" "unprognostic (8.13e-2)" "unprognostic (2.37e-1)" 18.3 11.6 17.5 10.4 18.7 12.8 9.5 14.4 23.1 8.8 8.5 11.2 18.2 9.5 11.2 11.9 9.2 11.2 14.1 19.5 17.2 27.7 35.3 11.4 10.4 15.8 16.9 6.8 8.8 17.2 13.4 8.3 17.4 9.4 11.5 18.2 8.7 9.3 17.6 11.1 13.0 11.5 13.6 16.6 11.4 12.4 18.0 14.6 10.4 21.2 12.4 14.8 8.4 18.3 18.3 30.5 14.6 19.5 31.0 16.7 11.6 19.2 27.9 33.8 27.5 30.1 16.4 14.4 16.3 28.6 18.3 26.6 53.9 22.5 29.8 16.6 18.0 13.1 18.8 18.4 23.8 17.2 23.2 23.6 19.3 34.3 20.6 16.3 27.8 17.5 14.0 23.0 23.6 32.7 18.1 12.2 34.6 34.6 31.2 11.5 14.8 24.6 44.2 21.2 22.8 30.7 22.3 40.0 26.1 25.6 30.1 27.8 22.7 19.6 16.4 22.0 23.1 23.4 19.2 21.5 21.6 17.8 19.8 14.2 18.2 19.3 9.3 19.1 9.6 8.2 7.4 8.9 13.4 5.4 6.0 7.3 70.5 9.4 16.1 5.8 7.3 13.5 17.5 18.7 14.4 23.1 19.5 17.2 15.8 16.9 17.4 13.6 18.0 18.3 16.4 12.8 22.4 7.5 11.1 27.8 6.2 5.5 10.8 14.4 33.0 25.4 41.1 11.5 11.5 9.2 20.9 5.2 12.0 10.4 5.9 6.0 114.1 17.9 12.3 16.6 6.0 9.5 12.0 5.6 4.0 15.6 12.2 35.4 5.1 5.3 11.7 34.0 7.5 20.2 12.4 11.7 8.2 11.3 34.4 95.6 7.2 19.1 12.4 6.5 10.1 8.2 22.6 5.5 11.6 6.2 6.1 5.7 10.2 6.6 13.8 17.1 5.2 9.0 19.7 40.7 10.8 9.6 10.3 17.6 34.1 8.2 12.8 7.3 8.5 6.9 SLC25A51 "CG7943, MCART1, MGC14836" ENSG00000122696 "Solute carrier family 25 member 51" Q9H1U9 9 37879400-37904353 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 93.6;Late spermatids: 169.6;Spermatocytes: 44.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 16.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 16.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046388, HPA058261" Uncertain Approved Mitochondria NA NA "Cluster 34: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "HPA046388: AB_2679649, HPA058261: AB_2683657" "unprognostic (5.46e-2)" "unprognostic (2.28e-1)" "unprognostic (2.67e-2)" "unprognostic (5.63e-2)" "unprognostic (1.00e-2)" "unprognostic (1.35e-2)" "prognostic unfavorable (5.67e-5)" "unprognostic (6.87e-2)" "unprognostic (1.04e-1)" "unprognostic (7.98e-3)" "unprognostic (1.26e-3)" "unprognostic (5.37e-2)" "prognostic favorable (1.52e-4)" "unprognostic (8.27e-3)" "unprognostic (2.31e-1)" "prognostic unfavorable (2.21e-4)" "unprognostic (2.08e-2)" 9.0 3.1 3.1 5.0 3.5 12.0 4.1 3.4 4.4 5.4 2.3 4.5 7.5 4.1 4.7 5.6 3.4 5.0 4.5 3.7 4.1 6.3 3.1 5.2 5.7 3.4 3.3 3.8 5.9 8.3 4.1 4.7 4.0 3.5 4.1 4.8 4.7 3.7 6.1 5.7 6.0 5.8 2.6 5.7 4.3 8.0 3.1 5.6 4.6 7.4 6.5 4.3 3.5 4.4 12.4 10.1 7.3 11.6 34.4 15.2 7.4 10.6 10.7 8.8 12.6 13.0 5.2 26.2 5.9 24.2 12.5 6.1 19.6 14.5 16.5 18.0 6.1 8.0 27.5 18.0 19.1 12.5 11.1 15.3 16.7 13.4 16.6 13.6 16.1 24.4 17.9 20.2 19.1 7.3 15.2 3.2 9.2 12.7 7.1 10.6 9.9 16.1 8.7 8.9 15.2 10.0 8.3 10.1 6.0 12.2 5.4 13.7 17.3 14.7 17.4 7.2 12.8 7.7 17.5 17.5 19.4 9.3 12.3 16.7 1.5 2.8 1.6 3.1 2.7 2.6 1.7 2.3 1.1 1.5 1.6 1.8 1.3 1.9 1.3 0.5 2.7 0.9 3.1 3.5 3.4 4.4 3.7 4.1 3.4 3.3 4.0 2.6 3.1 4.4 4.3 9.6 1.1 13.4 9.3 4.7 5.8 7.6 8.6 4.0 5.1 3.8 6.3 5.7 4.6 1.8 4.2 3.7 7.6 3.8 17.6 9.5 93.6 2.5 5.3 4.3 3.6 6.9 22.0 7.2 14.1 5.2 8.2 5.1 3.8 3.4 3.9 3.6 11.7 1.7 21.3 5.8 0.0 5.7 4.7 169.6 3.7 8.8 1.8 19.7 8.4 5.3 3.1 16.1 22.1 7.3 7.2 4.1 14.3 3.8 17.4 16.8 2.2 3.7 0.0 4.3 4.5 44.0 10.2 11.7 5.8 4.0 6.5 4.8 3.6 3.8 SLC25A52 MCART2 ENSG00000141437 "Solute carrier family 25 member 52" Q3SY17 18 31759584-31760880 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 14 "testis: 8.9" "Group enriched" "Detected in some" 4 "Early spermatids: 55.3;Late spermatids: 106.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046388, HPA058261" Uncertain Approved Mitochondria NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "HPA046388: AB_2679649, HPA058261: AB_2683657" "unprognostic (8.97e-2)" "unprognostic (4.85e-2)" "unprognostic (2.93e-1)" "unprognostic (4.87e-1)" "unprognostic (2.50e-1)" "unprognostic (9.05e-2)" "unprognostic (2.97e-2)" "unprognostic (1.30e-4)" "unprognostic (7.15e-3)" "unprognostic (1.23e-1)" "unprognostic (1.44e-1)" "unprognostic (1.41e-1)" "unprognostic (3.34e-2)" "unprognostic (1.55e-1)" "unprognostic (1.41e-2)" 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.6 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.1 0.0 8.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.5 0.1 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.3 0.2 0.2 0.0 0.0 0.1 0.3 0.3 0.1 0.1 0.1 0.1 0.2 0.3 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 106.9 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.6 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SLC27A1 "ACSVL5, FATP, FATP1, FLJ00336, MGC71751" ENSG00000130304 "Solute carrier family 27 member 1" Q6PCB7 19 17468769-17506168 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Lipid transport, Transport" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 84.5;Oligodendrocytes: 67.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 27.7;SK-MEL-30: 47.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076520 Approved "Plasma membrane,Mitochondria,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "Mitochondria, Cytosol" "HPA076520: AB_2732311" "unprognostic (1.48e-3)" "unprognostic (3.03e-2)" "unprognostic (5.72e-3)" "unprognostic (5.84e-2)" "unprognostic (2.16e-3)" "unprognostic (4.36e-2)" "unprognostic (8.56e-2)" "unprognostic (3.36e-2)" "unprognostic (9.03e-2)" "unprognostic (1.85e-2)" "unprognostic (1.12e-1)" "unprognostic (2.28e-1)" "prognostic favorable (4.70e-4)" "unprognostic (5.01e-2)" "unprognostic (2.25e-1)" "unprognostic (1.02e-1)" "unprognostic (1.12e-1)" 18.5 24.2 32.9 4.5 41.5 1.5 19.3 37.3 39.0 22.0 45.9 15.2 3.6 13.1 2.9 8.5 17.0 8.2 29.0 32.0 32.8 10.9 7.9 10.4 4.7 41.1 40.3 33.0 14.4 17.7 19.3 6.2 38.6 23.2 1.8 4.0 24.1 10.3 24.9 14.4 7.6 3.9 34.4 10.5 13.7 17.5 35.9 2.2 16.8 12.4 1.6 13.9 14.0 46.7 6.2 3.0 4.1 9.8 27.7 15.2 3.5 4.4 11.2 4.8 7.2 0.5 18.2 2.1 8.1 7.2 4.3 7.3 0.4 6.8 1.3 2.4 1.4 1.2 0.5 2.3 5.4 0.5 6.4 14.1 4.6 4.8 1.9 19.7 3.3 3.9 0.8 1.3 3.2 2.5 3.3 4.9 1.2 6.0 5.2 4.7 3.2 1.4 3.2 1.8 1.4 2.9 3.0 1.5 47.8 2.5 5.2 1.6 2.1 9.4 6.1 7.5 3.0 4.0 3.1 0.7 9.6 5.3 6.7 0.0 9.2 0.2 1.4 4.0 2.6 0.4 1.0 1.7 6.3 0.3 1.3 1.7 0.0 1.6 1.8 6.5 0.7 4.6 32.9 41.5 37.3 39.0 32.0 32.8 41.1 40.3 38.6 34.4 35.9 46.7 19.7 3.2 11.9 84.5 1.8 6.6 14.1 12.7 10.2 8.4 15.5 26.9 19.5 11.5 11.1 9.2 27.1 4.3 8.3 1.2 1.9 11.1 1.1 8.4 6.9 7.8 5.4 0.8 16.1 4.8 15.6 10.4 9.2 4.9 2.5 8.4 10.4 8.1 26.1 6.7 23.9 3.0 6.1 22.4 4.0 2.5 21.5 13.4 8.8 15.0 14.7 11.6 4.1 37.2 67.5 5.2 0.6 11.7 1.7 12.0 0.1 3.6 16.1 17.7 6.6 10.9 7.3 9.1 5.8 5.0 4.5 2.3 4.9 13.8 2.2 8.7 SLC37A4 "G6PT1, G6PT2, G6PT3, GSD1b, GSD1c, GSD1d" ENSG00000137700 "Solute carrier family 37 member 4" 11 119024114-119030906 "Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 139.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 171.6;Hepatocytes: 175.9;Proximal enterocytes: 277.2;Proximal tubular cells: 183.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 29.3;HEK 293: 28.0;Hep G2: 37.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038939, HPA038940" Enhanced Approved Mitochondria NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA038939: AB_2676279, HPA038940: AB_2676280" "unprognostic (4.77e-2)" "unprognostic (3.49e-1)" "unprognostic (2.08e-2)" "unprognostic (2.35e-2)" "unprognostic (4.70e-2)" "unprognostic (6.95e-3)" "unprognostic (1.09e-1)" "unprognostic (1.39e-1)" "unprognostic (4.08e-2)" "unprognostic (8.27e-3)" "unprognostic (4.72e-2)" "unprognostic (3.89e-1)" "unprognostic (1.98e-1)" "unprognostic (4.04e-2)" "unprognostic (2.60e-1)" "unprognostic (4.34e-2)" "unprognostic (5.39e-2)" 4.5 8.0 4.6 2.5 4.7 2.4 5.0 4.5 6.9 5.1 4.6 10.8 36.1 3.5 20.8 4.7 5.5 1.7 5.4 4.8 4.7 49.4 139.9 4.6 1.5 4.9 4.7 5.3 40.1 3.4 6.3 2.5 4.7 9.4 6.6 4.6 7.0 5.5 30.0 4.9 27.3 1.3 4.8 7.1 12.0 7.1 4.7 1.1 5.3 3.8 0.9 4.6 4.7 4.9 1.2 12.2 5.6 6.2 7.5 3.2 4.9 0.7 9.7 2.6 6.9 29.3 2.8 3.8 7.2 3.9 5.4 0.7 2.3 14.9 4.4 4.1 28.0 10.3 3.4 37.1 2.8 6.0 2.0 0.5 4.2 1.5 7.1 10.7 8.7 0.6 4.7 11.2 4.5 25.9 0.3 13.3 0.1 3.6 13.6 8.4 0.0 21.1 5.5 12.9 7.3 6.4 0.0 2.6 5.4 5.8 5.4 4.2 0.0 0.0 4.9 1.3 5.4 1.7 2.9 1.3 1.2 15.6 2.0 0.0 0.9 1.3 1.4 1.6 1.2 0.7 1.0 1.7 0.3 0.5 1.0 1.1 0.0 0.9 0.7 0.1 1.0 0.6 4.6 4.7 4.5 6.9 4.8 4.7 4.9 4.7 4.7 4.8 4.7 4.9 7.9 3.2 7.8 7.5 5.8 1.8 8.3 10.1 5.7 7.5 13.0 10.7 4.5 171.6 8.2 16.5 0.0 30.1 3.2 23.8 31.3 29.5 14.0 11.5 6.6 9.2 24.7 28.6 4.5 25.3 21.4 5.5 13.7 11.2 0.0 72.3 19.2 175.9 28.8 16.8 4.2 26.3 14.2 11.1 2.4 3.3 9.6 7.9 3.6 7.5 10.0 93.4 2.1 3.5 2.9 19.7 27.5 10.5 5.7 12.5 277.2 183.0 12.6 11.3 0.0 4.4 5.6 11.2 25.8 5.9 2.7 15.2 5.4 6.7 50.3 8.4 SLC3A1 "ATR1, CSNU1, D2H, NBAT, RBAT" ENSG00000138079 "Solute carrier family 3 member 1" Q07837 2 44275458-44321494 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Cystinuria, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 136.2;kidney: 649.3;pancreas: 217.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 74.4;Glandular and luminal cells: 128.9;Proximal enterocytes: 258.9;Proximal tubular cells: 363.0" "Cancer enriched" "Detected in many" 7 "renal cancer: 61.9" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 22 "RPTEC TERT1: 106.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA038360, HPA071102" Enhanced Approved "Nuclear bodies,Mitochondria" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "Nuclear bodies" "HPA038360: AB_2675975, HPA071102: AB_2732171" "unprognostic (1.67e-2)" "unprognostic (1.74e-1)" "unprognostic (1.39e-1)" "unprognostic (1.43e-2)" "unprognostic (6.14e-2)" "unprognostic (9.45e-2)" "unprognostic (2.76e-2)" "unprognostic (1.34e-1)" "unprognostic (3.90e-1)" "unprognostic (8.73e-2)" "unprognostic (1.16e-1)" "unprognostic (3.17e-1)" "prognostic favorable (3.67e-7)" "unprognostic (6.10e-2)" "unprognostic (1.26e-1)" "unprognostic (3.77e-1)" "unprognostic (1.58e-4)" 0.5 0.3 1.2 1.1 1.7 0.6 0.4 6.8 3.4 1.0 0.1 22.4 113.9 1.4 1.9 0.2 0.6 51.5 0.4 1.6 1.3 649.3 36.6 0.4 0.4 0.6 0.6 0.5 217.5 0.0 0.5 0.1 0.7 1.0 22.7 3.5 0.3 0.3 1.0 0.6 136.2 0.5 0.0 0.5 0.9 1.7 1.0 0.0 0.4 0.1 0.1 0.3 0.3 1.7 0.0 1.0 0.0 0.2 0.2 0.1 0.3 0.1 0.0 0.0 0.1 4.9 0.0 0.1 4.3 0.0 0.0 0.2 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.4 0.2 0.0 0.0 0.4 0.1 1.2 0.5 0.1 0.1 0.2 106.1 0.0 0.2 0.2 0.2 0.0 0.2 0.0 0.1 0.1 0.0 0.2 0.3 0.2 0.1 0.4 0.2 0.3 0.1 0.3 0.2 0.4 0.3 0.3 0.7 0.3 0.4 0.5 0.6 0.3 0.1 1.0 0.6 0.7 0.4 0.4 0.1 0.3 0.2 0.1 1.2 1.7 6.8 3.4 1.6 1.3 0.6 0.6 0.7 0.0 1.0 1.7 0.2 3.2 1.5 0.3 6.1 0.0 0.3 0.0 0.0 12.1 0.2 0.0 0.4 74.4 0.0 42.3 10.4 0.1 0.8 18.2 62.6 37.0 12.4 62.2 14.4 0.6 0.0 0.0 9.1 13.8 0.0 0.9 1.1 128.9 0.0 0.1 0.4 4.6 0.1 21.9 9.0 8.4 0.0 0.0 0.0 8.5 1.2 3.2 0.0 1.0 1.6 1.0 1.0 3.0 3.7 4.8 18.6 0.4 1.5 1.1 258.9 363.0 0.0 11.2 0.0 2.6 1.2 0.8 0.4 0.7 0.1 0.1 2.8 0.2 15.7 1.2 SLC41A1 MgtE ENSG00000133065 "Solute carrier family 41 member 1" Q8IVJ1 1 205789094-205813748 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 99.3;tongue: 75.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 175.0;Theca cells: 100.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014721, HPA015138" Uncertain Approved Mitochondria NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 38: Heart - Muscle contraction" "Cluster 44: HDLM-2 - Immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA014721: , HPA015138: AB_1857160" "unprognostic (1.18e-1)" "prognostic unfavorable (1.48e-4)" "unprognostic (2.77e-2)" "unprognostic (1.30e-2)" "unprognostic (2.30e-1)" "unprognostic (1.38e-2)" "unprognostic (2.37e-3)" "unprognostic (5.23e-2)" "unprognostic (5.53e-3)" "unprognostic (1.11e-1)" "unprognostic (1.87e-2)" "unprognostic (4.46e-2)" "unprognostic (3.09e-3)" "unprognostic (2.60e-1)" "unprognostic (1.67e-1)" "unprognostic (1.95e-1)" "unprognostic (1.65e-1)" 9.7 10.8 10.1 6.4 10.4 5.8 4.7 11.0 8.2 4.8 36.7 5.8 2.1 6.5 5.1 5.6 11.0 7.1 99.3 8.6 6.4 9.2 1.4 8.4 7.4 11.1 10.2 11.3 61.6 9.3 4.6 3.7 9.5 7.5 1.8 6.1 3.7 6.7 48.8 3.8 3.8 6.0 8.9 5.3 9.8 18.5 13.7 5.7 17.8 75.9 5.1 6.2 3.9 9.5 18.2 16.1 9.6 15.6 11.7 11.6 13.2 17.9 17.8 18.2 15.9 8.0 10.1 25.9 11.3 16.5 14.9 18.5 9.5 13.4 6.2 48.6 14.8 6.4 16.5 1.2 11.2 0.0 17.4 14.9 10.8 20.8 14.7 14.9 11.3 20.5 11.9 10.5 14.7 11.2 11.8 1.8 11.5 4.8 7.1 13.8 29.0 6.4 4.1 22.0 8.1 10.4 14.0 12.3 11.0 8.0 8.8 6.7 14.3 21.5 13.8 19.9 19.2 34.7 24.9 8.5 16.6 8.3 13.6 0.0 0.1 0.0 1.6 0.1 2.0 0.6 1.5 1.5 0.0 0.7 1.4 1.5 0.0 0.4 0.0 0.0 1.5 1.0 10.1 10.4 11.0 8.2 8.6 6.4 11.1 10.2 9.5 8.9 13.7 9.5 18.2 3.2 23.0 20.5 11.2 20.8 24.3 4.6 10.8 14.6 14.4 10.2 175.0 5.7 8.5 0.0 50.1 1.8 11.5 1.6 1.9 9.6 2.4 6.8 9.8 24.1 6.0 6.5 5.3 11.0 14.5 15.7 11.7 6.2 7.0 13.9 8.6 2.2 3.4 18.5 6.6 2.7 4.1 2.4 6.5 2.7 9.9 3.5 8.8 15.9 0.8 17.0 8.2 7.1 8.3 9.3 1.3 9.4 8.3 24.9 0.0 15.7 7.9 20.3 0.0 29.7 16.1 8.1 12.9 7.5 18.2 3.1 14.5 100.2 1.5 22.0 SLC51B OSTbeta ENSG00000186198 "Solute carrier family 51 subunit beta" Q86UW2 15 65045387-65053397 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 41.8;intestine: 107.1" "Cell type enhanced" "Detected in some" "Distal enterocytes: 354.6;Paneth cells: 145.1;Proximal enterocytes: 721.4" "Cancer enhanced" "Detected in many" "liver cancer: 9.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "CACO-2: 18.5;EFO-21: 11.9;Hep G2: 15.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA008398, HPA008533" Enhanced Approved Vesicles,Mitochondria No NA "Cluster 9: Intestine - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" Mitochondria Vesicles "HPA008398: , HPA008533: AB_1854824" "unprognostic (6.18e-2)" "unprognostic (6.75e-3)" "unprognostic (1.66e-1)" "unprognostic (1.31e-2)" "unprognostic (5.88e-2)" "unprognostic (9.49e-2)" "unprognostic (9.77e-3)" "unprognostic (1.81e-2)" "unprognostic (3.35e-2)" "unprognostic (2.76e-1)" "unprognostic (2.24e-1)" "unprognostic (4.34e-2)" "prognostic favorable (8.46e-5)" "unprognostic (5.87e-2)" "unprognostic (2.64e-2)" "unprognostic (1.05e-2)" "unprognostic (1.17e-2)" 0.7 1.1 5.8 3.5 5.5 0.8 0.3 4.0 3.9 41.8 0.0 41.9 86.9 3.0 0.3 2.4 3.6 2.8 2.3 3.8 6.5 19.5 2.2 6.1 0.6 7.3 10.9 1.1 0.3 0.0 0.4 0.6 7.7 2.7 29.4 0.7 1.0 0.6 1.0 0.8 107.1 1.7 6.5 0.8 0.8 9.6 11.8 0.0 0.7 0.0 0.0 1.5 0.9 4.2 0.0 1.5 0.2 0.8 0.0 0.1 0.4 0.0 0.0 0.2 0.0 18.5 0.0 0.1 11.9 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.1 15.7 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.2 0.2 0.0 0.4 0.1 0.4 0.4 0.1 0.4 0.0 0.0 0.9 0.4 0.0 0.6 0.5 0.0 0.0 0.0 2.2 0.5 0.0 0.0 0.3 0.0 0.1 0.2 0.2 0.4 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 5.5 4.0 3.9 3.8 6.5 7.3 10.9 7.7 6.5 11.8 4.2 0.0 0.0 1.1 0.3 1.3 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 1.5 0.7 0.0 0.0 0.1 0.0 354.6 13.7 0.0 60.8 10.4 0.2 1.2 1.8 2.7 0.0 0.0 0.0 0.5 0.0 1.9 4.5 0.0 0.4 1.8 0.1 0.0 0.0 23.0 0.0 0.3 0.0 14.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 145.1 0.0 0.0 0.0 721.4 73.3 15.6 0.0 6.6 1.0 0.4 27.9 0.5 0.0 0.0 0.1 0.6 0.1 45.8 0.0 SLC6A17 ENSG00000197106 "Solute carrier family 6 member 17" Q9H1V8 1 110150494-110202202 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 52.9;pituitary gland: 25.3" "Group enriched" "Detected in some" 5 "Excitatory neurons: 60.6;Inhibitory neurons: 59.4" "Cancer enriched" "Detected in some" 9 "melanoma: 17.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SK-MEL-30: 36.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008043, HPA008044" Enhanced Approved Mitochondria NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA008043: , HPA008044: AB_1857192" "unprognostic (1.13e-1)" "unprognostic (1.37e-3)" "unprognostic (5.52e-3)" "unprognostic (3.00e-2)" "unprognostic (1.17e-1)" "unprognostic (4.88e-2)" "unprognostic (6.11e-3)" "unprognostic (3.87e-3)" "unprognostic (1.70e-2)" "unprognostic (1.80e-1)" "unprognostic (1.68e-2)" "unprognostic (2.94e-1)" "unprognostic (1.89e-2)" "unprognostic (1.73e-2)" "unprognostic (9.76e-2)" "unprognostic (1.38e-3)" "unprognostic (1.68e-3)" 0.4 5.9 21.6 0.2 26.3 0.1 0.3 1.2 52.9 0.1 0.0 0.3 0.0 0.1 1.0 0.4 0.1 0.1 0.1 20.1 9.6 1.3 0.0 0.1 0.0 13.7 8.2 0.0 1.4 8.8 25.3 0.8 10.5 0.1 0.1 6.0 0.6 0.1 0.1 6.2 0.1 0.1 0.0 0.0 0.7 1.8 24.8 0.0 0.3 0.1 0.0 0.1 0.1 15.7 0.0 1.5 0.0 0.0 0.0 0.0 0.0 5.5 0.5 2.1 0.2 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.0 1.9 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 1.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.9 0.8 6.2 1.9 36.0 1.0 0.9 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 7.1 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.6 26.3 1.2 52.9 20.1 9.6 13.7 8.2 10.5 0.0 24.8 15.7 0.0 0.0 0.0 2.6 0.0 0.5 0.0 0.1 0.0 5.1 0.2 0.4 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.9 0.0 1.2 0.0 0.0 0.5 0.0 0.0 60.6 0.0 0.5 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 59.4 0.0 4.1 0.0 0.0 0.7 0.0 0.0 10.6 3.7 0.0 0.7 0.0 4.5 2.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.8 0.0 0.7 0.4 0.0 1.8 0.0 0.4 0.1 0.0 0.0 0.0 0.0 SLC6A2 "NAT1, NET, NET1, SLC6A5" ENSG00000103546 "Solute carrier family 6 member 2" P23975 16 55655604-55706192 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 149.4" "Group enriched" "Detected in some" 4 "Early spermatids: 4.3;Extravillous trophoblasts: 10.6;Late spermatids: 4.4;Spermatocytes: 11.5;Syncytiotrophoblasts: 5.6" "Cancer enhanced" "Detected in some" "liver cancer: 1.9" "Region enriched" "Detected in some" 10 "pons: 149.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 29 "SH-SY5Y: 489.1" "Region enriched" "Detected in some" 4 "pons and medulla: 7.8" "Region enriched" "Detected in single" 19 "pons: 13.8" "HPA004057, HPA076311, CAB078195" Enhanced Supported Approved Mitochondria,Cytosol NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol Mitochondria "CAB078195: AB_2665806, HPA004057: AB_1080012, HPA076311: AB_2732307" "unprognostic (9.58e-3)" "unprognostic (5.48e-2)" "unprognostic (1.26e-4)" "unprognostic (4.07e-1)" "unprognostic (4.16e-1)" "unprognostic (8.38e-2)" "unprognostic (2.97e-2)" "unprognostic (3.29e-1)" "unprognostic (2.31e-1)" "unprognostic (3.27e-1)" "unprognostic (2.12e-2)" "unprognostic (2.95e-2)" "unprognostic (1.72e-1)" "unprognostic (6.02e-2)" "unprognostic (8.48e-2)" "unprognostic (1.43e-2)" 0.9 21.7 0.1 0.0 0.1 0.0 0.8 0.0 0.2 2.4 0.0 0.2 0.1 5.4 0.2 0.2 0.5 0.1 0.0 0.1 0.0 0.4 0.4 0.1 0.0 3.8 14.6 0.1 0.0 0.5 0.0 12.6 149.4 0.2 0.3 0.0 1.9 0.6 0.0 13.3 0.2 0.8 0.1 0.0 0.1 6.2 0.0 0.1 0.0 0.0 0.1 0.2 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 5.2 3.7 489.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 3.8 14.6 149.4 0.1 0.0 0.5 1.8 0.0 0.0 0.0 0.0 1.5 0.2 0.4 0.0 0.0 0.3 0.1 0.8 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 4.3 0.1 0.0 0.3 0.0 0.0 0.0 0.0 10.6 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.5 4.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 11.5 0.3 0.0 0.4 5.6 0.0 0.0 0.0 0.1 SLITRK3 KIAA0848 ENSG00000121871 "SLIT and NTRK like family member 3" O94933 3 165186720-165197109 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.0;fallopian tube: 9.6;liver: 7.9" "Group enriched" "Detected in some" 6 "Bipolar cells: 8.4;Excitatory neurons: 11.0;Inhibitory neurons: 15.9;Oligodendrocyte precursor cells: 21.1" "Cancer enriched" "Detected in single" 22 "glioma: 7.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 2.6;HAP1: 2.2;SCLC-21H: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017636, HPA048042" Enhanced Approved Mitochondria No NA 2600000 "Cluster 15: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" Mitochondria "HPA017636: AB_1857232, HPA048042: AB_2732542" "unprognostic (8.91e-2)" "unprognostic (1.44e-1)" "unprognostic (4.08e-2)" "unprognostic (1.96e-1)" "unprognostic (5.16e-2)" "unprognostic (1.76e-1)" "unprognostic (9.59e-2)" "unprognostic (2.95e-2)" "unprognostic (1.03e-1)" "unprognostic (2.22e-1)" "unprognostic (6.74e-3)" "unprognostic (5.03e-1)" "unprognostic (2.38e-1)" "unprognostic (8.03e-4)" 0.1 0.1 3.4 1.0 3.1 0.0 0.1 4.1 8.4 5.4 0.0 2.6 0.4 7.3 0.9 4.4 9.6 0.2 0.4 9.0 2.8 0.1 7.9 0.3 0.0 0.2 0.1 0.9 0.0 0.0 0.1 0.0 0.5 1.7 1.6 3.1 0.2 5.4 0.3 0.0 1.1 3.7 0.9 0.0 0.4 0.4 0.7 0.0 0.1 0.0 0.0 0.5 0.9 1.3 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 3.1 4.1 8.4 9.0 2.8 0.2 0.1 0.5 0.9 0.7 1.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 11.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.7 2.2 0.0 0.0 15.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 21.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SMG9 "C19orf61, FLJ12886" ENSG00000105771 "SMG9 nonsense mediated mRNA decay factor" Q9H0W8 19 43727983-43754962 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Nonsense-mediated mRNA decay" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 103.2;Late spermatids: 329.5;Syncytiotrophoblasts: 95.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041763, HPA042096" Uncertain Approved "Plasma membrane,Mitochondria,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 78: Testis - Spermatogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Mitochondria, Cytosol" "Plasma membrane" "HPA041763: AB_2677659, HPA042096: AB_2677845" "unprognostic (2.22e-1)" "unprognostic (1.32e-1)" "unprognostic (7.41e-2)" "unprognostic (6.46e-2)" "unprognostic (2.71e-1)" "unprognostic (1.55e-2)" "prognostic unfavorable (2.15e-5)" "unprognostic (2.71e-1)" "unprognostic (4.11e-2)" "unprognostic (9.24e-3)" "unprognostic (3.88e-2)" "unprognostic (8.76e-2)" "prognostic unfavorable (1.71e-4)" "unprognostic (8.00e-2)" "unprognostic (1.27e-1)" "unprognostic (2.36e-1)" "prognostic favorable (8.09e-4)" 9.0 11.7 10.3 10.9 10.8 8.4 8.7 10.9 13.5 10.6 5.9 9.0 8.0 9.0 7.7 9.2 7.7 6.8 7.7 10.2 10.6 7.7 6.6 10.0 13.0 13.1 11.6 7.8 5.8 8.8 9.4 10.1 13.6 11.5 6.2 5.9 12.0 6.9 7.5 10.7 10.0 8.1 9.5 13.5 8.7 33.8 11.6 11.8 8.3 7.1 12.0 10.0 9.9 14.9 25.3 27.2 19.5 12.5 13.4 18.9 13.1 35.1 20.8 38.4 28.7 19.4 32.5 27.4 16.9 24.1 13.2 10.7 22.9 19.7 24.9 21.1 13.2 49.2 20.5 12.9 15.6 37.4 25.9 10.1 16.6 27.9 29.6 32.1 15.8 25.0 37.7 23.6 18.0 17.9 39.9 10.6 9.4 48.0 18.2 21.2 16.1 12.3 20.4 20.4 32.4 15.9 36.7 27.4 21.3 15.4 16.6 20.5 19.2 59.7 35.4 22.3 27.1 11.5 26.8 33.4 17.9 28.4 49.7 1.0 5.3 3.3 5.1 7.7 4.5 7.4 5.1 4.3 6.9 5.3 6.7 4.5 1.3 4.2 11.7 6.1 4.1 11.3 10.3 10.8 10.9 13.5 10.2 10.6 13.1 11.6 13.6 9.5 11.6 14.9 7.7 32.1 8.3 20.9 13.7 9.3 15.0 16.8 11.4 13.2 10.0 11.0 4.4 4.3 9.0 9.2 4.2 49.5 11.3 9.5 1.9 12.2 103.2 5.5 7.0 12.0 4.2 7.8 19.5 8.7 15.8 11.4 15.8 8.9 9.5 12.1 11.0 3.3 21.4 13.5 23.0 11.3 8.2 10.3 9.2 329.5 13.1 12.1 10.6 11.2 16.2 6.0 4.1 16.1 29.6 13.6 9.2 12.0 11.2 15.9 8.5 6.8 8.4 9.2 6.6 11.2 8.5 42.6 16.2 8.4 7.1 95.4 9.3 11.8 12.2 11.1 SMIM12 "C1orf212, FLJ90372" ENSG00000163866 "Small integral membrane protein 12" Q96EX1 1 34712737-34859755 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065331 Approved Approved Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA065331: AB_2685470" "unprognostic (2.21e-1)" "unprognostic (2.26e-1)" "unprognostic (3.68e-2)" "unprognostic (1.24e-1)" "unprognostic (1.97e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.18e-4)" "unprognostic (2.64e-1)" "unprognostic (2.05e-1)" "unprognostic (5.71e-2)" "unprognostic (3.57e-2)" "unprognostic (1.93e-1)" "prognostic favorable (1.15e-5)" "unprognostic (7.33e-2)" "unprognostic (6.70e-2)" "unprognostic (3.58e-2)" "unprognostic (2.52e-2)" 40.2 56.6 31.7 26.5 32.1 24.8 33.5 29.5 35.3 20.9 29.2 34.0 30.1 26.0 17.7 41.3 23.5 17.3 53.8 31.5 35.7 42.3 87.9 31.6 25.0 32.6 32.7 17.1 26.4 31.8 26.9 24.8 33.1 19.9 28.0 12.8 24.1 20.5 56.2 29.7 30.8 31.5 29.6 31.9 30.4 28.0 31.9 30.3 24.9 51.1 27.3 29.2 25.7 33.3 52.9 39.8 43.3 31.6 55.2 43.3 30.1 55.8 48.1 70.2 60.3 40.0 65.0 55.1 49.2 57.6 55.5 51.7 55.5 74.7 53.5 67.3 41.6 98.1 65.6 49.1 51.3 107.9 55.4 66.2 71.9 76.5 61.3 25.3 72.9 47.0 71.0 72.3 63.0 38.6 52.6 55.4 70.1 40.8 52.7 44.1 42.7 71.7 62.2 54.6 41.5 32.9 52.0 48.1 81.5 53.9 32.8 29.9 69.9 47.8 49.3 74.3 66.7 40.4 60.2 56.9 45.2 63.7 32.1 104.2 76.0 126.4 65.8 82.0 77.9 57.7 60.4 72.0 86.0 59.2 50.1 64.3 50.2 62.6 67.5 62.4 76.2 87.5 31.7 32.1 29.5 35.3 31.5 35.7 32.6 32.7 33.1 29.6 31.9 33.3 51.2 25.6 13.1 4.9 37.0 68.2 26.3 49.8 23.3 14.4 36.4 30.1 33.9 42.9 30.4 22.0 10.4 50.7 38.5 46.7 86.1 78.7 58.3 17.1 19.0 56.2 21.8 53.9 10.4 83.7 60.2 24.9 20.9 20.6 23.5 18.9 48.2 89.3 83.8 20.2 9.5 23.4 46.8 41.7 61.6 32.7 14.9 41.0 39.2 7.5 89.8 24.9 54.6 6.6 7.0 87.5 41.0 23.3 27.5 40.8 62.9 90.6 26.8 17.3 13.1 21.8 52.3 37.6 23.0 41.4 75.6 58.0 40.8 33.7 39.6 41.7 SMIM4 C3orf78 ENSG00000168273 "Small integral membrane protein 4" Q8WVI0 3 52534013-52579237 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 121.9;skeletal muscle: 130.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 252.4;Distal tubular cells: 213.2;Proximal tubular cells: 215.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047771 Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Mitochondria" "HPA047771: AB_2680150" "unprognostic (3.76e-3)" "unprognostic (3.19e-2)" "unprognostic (4.54e-2)" "unprognostic (4.89e-1)" "unprognostic (2.40e-1)" "unprognostic (1.48e-2)" "unprognostic (9.89e-2)" "prognostic favorable (1.78e-5)" "unprognostic (3.25e-2)" "unprognostic (4.25e-2)" "prognostic favorable (5.00e-4)" "unprognostic (6.35e-2)" "prognostic favorable (1.63e-4)" "unprognostic (8.72e-3)" "unprognostic (2.28e-1)" "unprognostic (1.67e-1)" "unprognostic (1.09e-2)" 22.6 121.9 14.6 12.9 15.3 7.4 22.1 21.8 20.5 16.0 20.5 19.1 12.3 14.3 10.4 16.3 14.5 3.7 100.3 15.3 15.5 37.3 20.2 20.3 10.5 15.6 18.2 41.5 25.7 31.6 56.4 6.1 16.9 26.2 10.4 13.9 28.9 13.6 130.3 20.1 15.0 5.0 15.0 15.8 20.4 17.3 15.4 6.6 48.6 50.2 8.7 20.2 13.3 18.0 58.7 19.0 22.9 58.5 26.5 13.7 47.0 25.9 12.0 29.2 25.3 24.6 15.4 25.1 11.6 10.9 29.4 30.2 7.6 20.9 11.8 16.9 60.1 23.6 58.2 50.2 40.1 28.4 31.6 29.6 12.7 24.6 17.7 15.8 26.8 27.0 31.9 36.4 19.9 25.4 26.4 39.4 39.1 31.9 42.4 18.1 22.2 50.1 17.0 25.2 24.9 31.4 50.6 16.5 52.6 12.9 17.0 23.6 24.0 16.0 53.1 76.4 53.5 42.3 50.6 57.3 87.9 52.2 22.5 8.1 44.1 17.3 19.1 35.8 18.8 24.6 27.3 23.9 49.7 22.7 29.1 27.0 1.6 22.5 15.2 26.5 29.6 20.0 14.6 15.3 21.8 20.5 15.3 15.5 15.6 18.2 16.9 15.0 15.4 18.0 35.4 48.1 46.3 1.3 30.3 27.1 37.3 52.2 41.5 17.6 80.9 84.1 252.4 60.1 63.1 53.3 12.5 42.9 26.6 58.3 213.2 52.9 21.9 71.9 30.6 32.8 79.3 22.1 1.9 86.1 24.7 36.0 34.1 48.9 59.5 16.9 55.6 160.4 116.4 3.3 2.1 62.9 30.5 80.8 46.7 15.1 65.0 51.1 37.4 0.0 28.5 102.8 15.5 2.5 3.2 57.8 39.9 101.2 19.7 19.7 89.5 215.6 52.1 15.3 46.0 22.8 56.8 9.8 14.2 34.8 34.5 27.6 25.8 44.3 73.5 23.6 SMPDL3A "ASM3A, ASML3a, FLJ20177, yR36GH4.1" ENSG00000172594 "Sphingomyelin phosphodiesterase acid like 3A" Q92484 6 122789049-122809720 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 156.3;Distal enterocytes: 291.5;Paneth cells: 157.5;Proximal enterocytes: 383.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "basophil: 80.9" "Lineage enriched" "Detected in many" 11 "granulocytes: 80.9" "Cell line enhanced" "Detected in many" "ASC diff: 44.2;hTCEpi: 36.9;OE19: 58.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030148 Uncertain Approved Nucleoplasm,Nucleoli,Mitochondria "Secreted to blood" No No 26000000 "Cluster 46: Basophils - DNA binding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Nucleoli, Mitochondria" "HPA030148: AB_10601591" "unprognostic (2.60e-1)" "unprognostic (1.22e-1)" "prognostic favorable (6.11e-4)" "unprognostic (1.23e-1)" "unprognostic (1.15e-1)" "unprognostic (8.30e-3)" "unprognostic (3.37e-1)" "unprognostic (1.46e-1)" "unprognostic (1.83e-1)" "unprognostic (1.53e-1)" "unprognostic (1.39e-1)" "unprognostic (7.72e-2)" "unprognostic (2.27e-2)" "unprognostic (3.44e-2)" "unprognostic (8.46e-2)" "unprognostic (1.17e-2)" "unprognostic (1.11e-1)" 15.0 23.3 4.6 18.7 5.1 22.9 23.7 8.2 9.4 72.8 8.9 60.7 45.5 13.3 6.5 13.6 7.9 17.2 5.6 5.3 5.7 47.4 80.0 14.1 21.4 5.9 5.4 9.1 20.8 32.4 7.5 44.0 5.9 21.8 65.7 6.0 13.7 16.6 39.8 64.5 77.3 8.5 5.7 27.0 30.5 2.9 5.4 5.1 9.1 55.8 16.2 35.5 30.9 7.7 0.3 2.6 6.1 2.8 44.2 19.9 19.5 10.4 27.8 3.1 6.6 3.3 2.7 0.0 1.4 6.6 8.2 4.9 1.7 5.3 2.6 0.0 5.4 2.5 9.8 9.0 28.3 0.0 0.1 24.4 36.9 3.0 5.3 12.0 5.5 0.0 3.8 0.0 12.7 9.3 0.0 0.2 1.1 58.8 8.0 0.0 10.8 0.4 15.1 4.2 4.4 0.1 1.5 18.5 27.9 3.9 3.1 1.4 11.0 5.9 3.5 0.6 6.8 0.0 0.0 0.0 8.7 4.9 13.7 80.9 4.0 1.1 0.0 4.3 0.0 0.2 0.0 0.0 0.9 0.0 0.0 0.0 1.3 0.0 7.5 0.0 0.0 1.4 4.6 5.1 8.2 9.4 5.3 5.7 5.9 5.4 5.9 5.7 5.4 7.7 11.8 3.2 17.8 5.2 2.4 53.7 24.5 13.7 15.9 3.0 12.2 6.6 4.0 25.8 9.7 5.5 4.2 156.3 0.4 291.5 56.7 24.6 0.2 4.2 12.6 7.1 48.7 5.7 7.4 25.7 40.4 46.3 34.7 5.2 10.1 0.8 18.9 77.8 62.7 3.3 10.5 61.7 59.0 126.3 10.0 1.2 15.5 33.4 35.6 11.2 9.9 11.5 2.1 11.1 11.0 19.5 157.5 14.3 0.9 16.7 383.1 129.3 7.5 6.2 13.1 12.8 9.9 1.1 3.7 15.5 76.0 115.1 2.0 11.4 38.9 16.6 SMYD2 "HSKM-B, KMT3C, ZMYND14" ENSG00000143499 "SET and MYND domain containing 2" Q9NRG4 1 214281102-214337131 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "heart muscle: 198.8;skeletal muscle: 92.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 148.0;Cytotrophoblasts: 168.7;Early spermatids: 134.5;Extravillous trophoblasts: 110.5;Late spermatids: 120.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029023 Uncertain Approved Mitochondria,Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 38: Heart - Muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol Mitochondria "HPA029023: AB_10601605" "unprognostic (8.53e-2)" "prognostic unfavorable (1.53e-5)" "unprognostic (5.98e-2)" "unprognostic (1.00e-2)" "unprognostic (8.55e-2)" "unprognostic (2.53e-2)" "unprognostic (2.24e-2)" "unprognostic (1.72e-2)" "unprognostic (1.90e-3)" "unprognostic (1.65e-1)" "unprognostic (9.44e-2)" "unprognostic (2.77e-1)" "prognostic favorable (8.68e-4)" "unprognostic (2.65e-1)" "unprognostic (4.92e-2)" "unprognostic (8.10e-2)" "unprognostic (6.37e-2)" 15.5 15.0 12.4 9.0 13.0 8.9 18.7 13.5 32.1 12.2 17.8 12.9 13.8 9.5 7.5 18.1 27.6 9.3 198.8 14.6 16.1 20.4 26.2 18.1 13.5 14.7 16.7 12.0 19.1 6.9 17.1 27.3 14.2 12.1 14.3 14.3 13.7 8.1 92.4 11.4 12.6 10.1 14.5 15.1 19.2 24.3 14.4 22.6 20.3 4.2 14.2 11.8 10.1 14.4 64.4 14.5 22.7 16.8 21.7 37.7 102.4 36.6 28.8 41.8 46.6 68.3 52.0 34.6 36.7 39.8 19.7 28.9 21.3 63.5 36.8 28.3 29.8 10.1 30.0 46.7 19.9 47.6 7.4 42.9 31.2 30.5 21.6 27.2 32.1 29.5 35.0 7.5 36.4 33.5 32.6 26.1 21.3 32.4 26.3 20.6 59.9 27.8 33.9 45.2 23.7 55.3 28.9 95.0 73.3 47.8 75.5 30.1 38.6 32.9 49.6 18.0 55.2 33.2 13.0 39.2 43.1 35.1 37.8 15.8 10.0 14.4 15.0 5.7 17.8 15.4 22.5 19.9 9.5 7.5 19.3 18.0 0.9 29.2 1.9 6.4 26.7 13.0 12.4 13.0 13.5 32.1 14.6 16.1 14.7 16.7 14.2 14.5 14.4 14.4 10.5 19.2 9.7 7.5 13.7 20.6 16.5 40.0 25.0 8.7 16.8 19.9 148.0 24.3 17.7 3.7 0.0 168.7 12.2 10.0 31.3 34.3 134.5 48.7 9.9 15.6 4.2 8.6 60.7 20.0 110.5 11.1 11.7 17.4 3.8 27.9 17.2 20.3 38.4 15.2 26.9 13.4 14.2 21.5 10.6 120.4 11.8 11.4 16.0 22.5 11.7 28.1 9.2 7.1 10.3 26.1 11.7 3.8 16.4 16.1 21.9 34.6 69.6 8.0 13.1 6.8 16.7 13.9 39.6 28.9 18.0 85.9 16.8 30.0 19.3 10.9 SMYD5 "NN8-4AG, RAI15, RRG1, ZMYND23" ENSG00000135632 "SMYD family member 5" Q6GMV2 2 73214222-73227221 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015514, HPA049002" Uncertain Approved Mitochondria NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA015514: AB_2669205, HPA049002: AB_2680595" "unprognostic (1.75e-1)" "unprognostic (3.39e-1)" "unprognostic (5.22e-2)" "unprognostic (6.66e-3)" "unprognostic (3.86e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (6.58e-7)" "unprognostic (1.28e-1)" "unprognostic (1.60e-2)" "unprognostic (3.84e-2)" "unprognostic (3.84e-1)" "unprognostic (2.49e-1)" "unprognostic (3.03e-2)" "unprognostic (3.94e-1)" "unprognostic (1.47e-1)" "unprognostic (1.91e-1)" "unprognostic (2.40e-1)" 13.3 19.1 27.2 12.1 27.8 11.6 14.8 24.3 30.5 15.5 22.0 12.5 7.3 14.4 19.4 14.1 19.5 7.3 17.9 28.2 28.0 18.8 15.2 9.8 13.1 28.9 26.5 28.3 18.4 17.9 15.4 13.1 28.8 15.4 11.3 13.0 12.2 13.4 17.7 14.5 12.4 14.5 25.9 16.2 11.4 17.4 26.9 8.2 14.3 13.0 16.0 17.5 13.1 26.9 24.3 45.2 27.0 25.9 19.3 28.4 45.7 22.8 23.0 43.4 26.6 59.4 24.4 43.1 20.9 38.6 52.1 24.4 42.2 49.4 39.1 26.3 29.7 41.8 19.5 65.9 26.0 41.5 16.5 24.0 31.4 39.7 47.3 19.2 26.7 33.9 44.9 20.2 27.9 34.1 38.8 27.1 42.2 50.8 36.3 25.6 50.6 35.5 28.6 34.6 17.4 25.9 20.7 30.7 26.4 24.4 25.0 14.7 18.5 29.7 46.3 36.5 38.1 22.0 17.7 38.2 33.5 35.2 24.3 0.0 1.4 0.0 5.1 3.9 11.1 6.0 7.0 6.8 3.2 6.2 7.0 7.7 0.0 4.5 4.3 3.0 3.1 4.5 27.2 27.8 24.3 30.5 28.2 28.0 28.9 26.5 28.8 25.9 26.9 26.9 4.1 3.2 5.6 5.2 5.6 5.1 3.9 2.3 1.8 10.2 5.4 6.7 7.2 2.8 4.4 5.5 4.2 9.0 3.4 2.4 1.9 8.5 0.5 2.8 4.2 4.9 0.0 9.5 5.0 8.8 10.4 4.5 2.6 3.7 7.0 9.5 2.9 4.8 5.9 5.0 5.2 4.4 4.1 2.4 2.5 2.9 2.8 2.7 5.4 2.8 3.7 4.0 4.1 1.5 3.5 5.6 1.5 3.0 3.1 5.0 1.3 8.1 1.3 5.3 6.6 4.0 4.6 6.7 11.1 5.7 3.4 4.8 4.5 4.6 5.6 3.6 SNX19 "CHET8, KIAA0254" ENSG00000120451 "Sorting nexin 19" Q92543 11 130866250-130916479 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 112.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013447 Uncertain Approved Mitochondria NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 35: Non-specific - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 46: Photoreceptor cells - Phototransduction" Mitochondria "HPA013447: AB_1857347" "unprognostic (8.79e-3)" "unprognostic (1.82e-1)" "unprognostic (1.45e-1)" "unprognostic (1.56e-1)" "unprognostic (2.97e-2)" "unprognostic (2.43e-1)" "unprognostic (4.17e-2)" "unprognostic (9.19e-2)" "unprognostic (3.43e-2)" "unprognostic (4.05e-2)" "unprognostic (2.89e-1)" "unprognostic (4.97e-2)" "prognostic favorable (3.56e-5)" "unprognostic (1.05e-1)" "unprognostic (2.77e-1)" "unprognostic (2.92e-2)" "unprognostic (1.55e-2)" 15.9 18.5 19.0 12.4 24.3 8.7 14.8 18.0 17.9 15.5 18.2 22.3 11.8 18.0 19.1 14.7 16.3 14.9 20.1 15.3 17.6 16.6 19.3 14.6 11.0 27.4 22.5 14.0 19.4 16.1 17.2 12.6 21.1 16.6 14.1 15.5 19.4 14.4 23.8 12.9 15.4 19.5 22.1 15.2 19.0 21.3 23.8 11.1 21.5 13.1 11.7 19.1 13.5 28.7 13.8 23.2 17.4 27.7 52.9 36.9 13.2 35.7 38.1 17.9 18.1 20.6 26.2 12.4 27.0 40.3 45.3 25.6 3.2 25.1 20.8 20.9 13.7 24.3 18.3 0.1 30.9 0.0 19.1 42.1 24.4 20.0 17.9 35.3 20.9 17.9 23.5 0.1 35.3 10.9 18.6 10.6 4.9 30.0 19.3 16.1 17.2 8.0 11.9 27.8 19.6 16.4 16.7 22.4 11.1 13.4 46.6 13.0 34.4 26.7 20.9 21.8 21.3 4.5 0.0 0.1 9.7 13.5 28.9 6.5 3.6 2.5 2.1 3.2 3.0 2.8 1.9 2.5 2.9 1.8 2.3 2.0 1.7 1.6 4.0 2.7 1.9 3.5 19.0 24.3 18.0 17.9 15.3 17.6 27.4 22.5 21.1 22.1 23.8 28.7 12.6 25.6 7.9 44.4 14.8 4.0 7.2 7.8 8.6 25.6 11.6 9.1 20.4 15.7 12.9 23.9 10.4 10.3 10.0 19.4 9.8 11.5 35.8 10.8 14.3 12.2 11.4 7.4 30.0 16.0 5.7 11.4 15.8 11.0 18.4 13.5 13.9 21.3 10.1 16.8 34.9 12.5 6.1 11.7 5.2 44.7 13.7 11.9 3.6 20.6 9.6 22.4 13.4 35.7 112.6 16.6 14.5 15.8 15.5 10.2 14.4 8.6 16.9 37.9 13.1 12.7 9.8 37.1 15.5 9.8 4.3 14.0 9.2 13.1 10.3 10.8 SP140 "LYSP100-A, LYSP100-B" ENSG00000079263 "SP140 nuclear body protein" Q13342 2 230203110-230313215 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 15.6;lymphoid tissue: 55.8" "Cell type enhanced" "Detected in many" "B-cells: 149.9;dendritic cells: 37.4;NK-cells: 50.4;Plasma cells: 77.2;T-cells: 62.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "memory B-cell: 97.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 31.1;HDLM-2: 52.4;Karpas-707: 25.2;RPMI-8226: 16.3" "Low region specificity" "Detected in all" "HPA006162, HPA067493" Enhanced Approved "Nucleoli fibrillar center,Mitochondria" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 57: B-cells - Immune response" "Nucleoli fibrillar center" Mitochondria "HPA006162: AB_1857403, HPA067493: AB_2685851" "unprognostic (8.15e-3)" "unprognostic (2.25e-3)" "unprognostic (3.90e-3)" "unprognostic (5.72e-4)" "unprognostic (5.66e-2)" "unprognostic (3.33e-4)" "unprognostic (1.09e-1)" "unprognostic (1.03e-1)" "unprognostic (6.05e-2)" "unprognostic (1.12e-3)" "unprognostic (3.89e-2)" "unprognostic (2.88e-1)" "unprognostic (1.20e-9)" "unprognostic (9.12e-2)" "unprognostic (8.50e-2)" "unprognostic (3.66e-1)" "unprognostic (9.30e-3)" 1.7 0.8 0.7 25.0 0.8 6.6 1.2 0.8 1.6 0.6 1.0 3.5 2.9 0.9 0.8 0.9 0.7 2.9 0.6 0.8 1.1 0.9 1.6 4.4 54.6 1.8 1.2 0.4 0.3 0.2 0.6 1.2 1.5 0.9 3.9 1.0 2.6 0.5 0.2 1.6 15.6 1.0 1.3 27.8 5.1 1.5 2.1 6.8 1.3 0.1 55.8 4.3 0.7 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 2.4 0.0 0.3 31.1 0.0 0.0 5.2 0.0 0.0 0.1 1.8 52.4 0.0 0.0 0.0 0.6 0.2 4.4 0.1 0.5 0.0 0.5 0.6 0.4 0.0 0.3 0.0 25.2 0.6 0.0 0.0 1.5 1.3 0.0 0.0 0.1 2.8 16.3 8.8 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.6 0.1 0.3 1.3 0.0 0.0 9.2 4.0 1.1 2.2 0.7 0.0 0.1 3.5 12.0 23.1 7.3 25.6 97.5 22.8 25.3 8.3 71.0 11.5 15.0 33.4 15.1 10.6 0.5 22.5 10.6 0.7 0.8 0.8 1.6 0.8 1.1 1.8 1.2 1.5 1.3 2.1 1.5 1.6 0.0 2.3 3.9 149.9 0.9 0.0 0.2 0.0 0.7 0.3 0.5 0.5 0.0 0.8 0.0 8.4 0.1 37.4 0.1 0.0 0.0 17.2 0.5 0.2 1.1 0.0 9.7 5.0 0.0 0.2 0.8 1.5 0.1 0.0 0.2 2.2 0.9 11.4 0.0 5.0 0.1 0.0 8.4 8.6 4.8 0.0 13.2 7.2 26.2 13.7 0.5 50.4 2.5 2.8 0.1 0.1 1.2 77.2 0.1 0.0 0.4 2.4 1.7 0.0 0.2 1.0 1.2 0.4 0.7 1.1 0.3 62.1 0.3 0.2 0.2 SP9 ZNF990 ENSG00000217236 "Sp9 transcription factor" P0CG40 2 174334954-174338500 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 3.2" "Cell type enriched" "Detected in some" 5 "Inhibitory neurons: 11.1" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 7.2;fHDF/TERT166: 5.5;HEK 293: 2.2;THP-1: 11.6" "Group enriched" "Detected in many" 6 "basal ganglia: 5.8;olfactory bulb: 11.7" "Group enriched" "Detected in many" 4 "basal ganglia: 5.6;olfactory bulb: 21.6" HPA062616 Uncertain Approved Mitochondria NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA062616: AB_2684808" "unprognostic (2.04e-2)" "unprognostic (6.94e-3)" "unprognostic (1.44e-1)" "unprognostic (3.95e-1)" "unprognostic (7.55e-3)" "unprognostic (8.54e-2)" "unprognostic (3.12e-1)" "unprognostic (1.01e-1)" 0.0 0.0 2.5 0.0 2.9 0.0 0.2 0.0 3.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.7 1.6 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.2 7.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 5.5 0.0 0.1 0.2 0.0 0.0 0.0 2.2 0.5 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.1 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 1.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 2.9 0.0 3.2 0.7 1.6 0.1 0.3 0.1 0.0 0.6 0.4 0.2 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 1.3 0.5 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.7 0.5 0.0 0.1 0.0 0.1 0.1 0.0 0.0 SPACA9 "C9orf9, Mast" ENSG00000165698 "Sperm acrosome associated 9" Q96E40 9 132878027-132890201 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 74.0;testis: 131.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 23.9;Distal tubular cells: 33.2;Endometrial ciliated cells: 99.8;Proximal tubular cells: 23.9;Respiratory ciliated cells: 63.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 4 "JURKAT: 48.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA022243, HPA051600" Enhanced Approved Mitochondria No No "Cluster 19: B-cells - Humoral immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" Mitochondria "HPA022243: AB_1845844, HPA051600: AB_2681546" "unprognostic (2.69e-1)" "unprognostic (2.14e-3)" "unprognostic (8.00e-3)" "prognostic favorable (8.61e-4)" "unprognostic (1.59e-1)" "unprognostic (5.73e-2)" "unprognostic (3.76e-3)" "unprognostic (2.60e-1)" "unprognostic (6.43e-2)" "unprognostic (1.12e-1)" "unprognostic (1.15e-2)" "unprognostic (9.51e-2)" "prognostic favorable (8.31e-4)" "unprognostic (5.11e-2)" "unprognostic (1.22e-2)" "unprognostic (1.20e-1)" "unprognostic (1.22e-2)" 5.0 7.6 17.4 1.3 17.7 1.5 5.2 17.4 19.5 9.7 18.2 11.5 1.3 8.3 74.0 9.5 39.2 5.4 10.4 16.8 19.0 12.2 2.3 7.4 2.2 20.3 22.2 11.3 5.2 3.8 11.5 3.2 19.1 7.0 1.9 8.2 9.8 7.1 1.7 11.9 3.7 4.9 21.3 3.6 6.5 131.2 18.5 7.9 15.6 1.8 3.2 6.1 8.1 19.0 3.0 3.2 4.8 3.9 6.6 8.4 5.7 1.9 3.5 2.6 2.8 0.8 9.1 0.7 4.3 8.7 5.4 4.2 2.0 5.4 2.3 3.5 3.9 0.8 2.3 1.0 9.6 2.2 0.3 9.6 11.4 6.4 6.9 10.6 3.0 48.5 0.8 2.4 7.1 6.4 7.6 8.6 1.0 5.6 3.0 3.6 1.0 2.1 10.5 1.1 1.2 4.7 8.0 1.3 6.3 3.6 10.3 0.7 2.9 5.5 3.7 5.3 0.8 1.0 1.7 2.6 10.2 0.8 2.7 4.0 1.1 1.9 1.1 1.1 1.3 3.0 1.2 0.6 1.6 2.6 1.3 1.3 1.5 4.4 1.9 0.5 2.0 0.9 17.4 17.7 17.4 19.5 16.8 19.0 20.3 22.2 19.1 21.3 18.5 19.0 3.6 3.2 2.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 10.3 17.9 0.0 0.0 5.0 23.9 0.0 18.2 0.8 0.0 33.2 8.6 0.0 99.8 7.1 1.9 0.0 0.0 0.0 7.1 12.4 3.9 0.0 8.1 0.0 6.7 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 23.9 63.4 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 7.3 0.8 7.7 0.0 0.0 SPATA2L "C16orf76, MGC26885, tamo" ENSG00000158792 "Spermatogenesis associated 2 like" Q8IUW3 16 89696357-89701705 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 34.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041182, HPA042453" Uncertain Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Mitochondria" Cytosol "HPA041182: AB_2677352, HPA042453: AB_2678005" "unprognostic (1.22e-1)" "unprognostic (9.04e-2)" "unprognostic (5.23e-2)" "unprognostic (9.13e-3)" "unprognostic (2.21e-1)" "unprognostic (6.62e-2)" "unprognostic (2.72e-2)" "unprognostic (2.13e-1)" "unprognostic (4.86e-2)" "unprognostic (9.25e-2)" "unprognostic (1.40e-3)" "unprognostic (5.32e-2)" "unprognostic (2.36e-3)" "unprognostic (8.86e-2)" "unprognostic (4.19e-2)" "unprognostic (5.84e-2)" "unprognostic (2.55e-1)" 6.7 5.1 5.7 2.3 6.6 5.0 4.9 4.8 8.7 3.9 5.2 6.2 5.9 6.1 0.7 5.8 6.2 2.2 4.9 8.0 4.9 10.3 13.6 7.1 1.5 4.9 3.8 5.4 14.2 2.2 16.7 1.8 3.1 5.9 0.8 0.6 5.7 1.3 1.3 7.7 7.1 1.4 2.6 6.0 6.9 4.9 4.2 1.7 7.0 0.3 0.8 3.8 3.5 6.3 7.4 5.8 2.0 9.6 1.5 1.6 10.7 4.9 2.3 2.3 1.5 11.1 6.2 2.5 6.6 1.6 3.1 12.5 1.8 2.8 0.5 2.5 19.9 1.7 2.2 15.3 5.1 1.3 5.0 1.6 3.5 3.6 1.1 2.6 2.6 2.9 7.7 1.7 1.6 34.0 4.3 8.0 5.4 7.6 7.5 9.4 1.0 7.4 3.4 2.6 11.0 7.0 5.3 5.4 6.5 0.9 14.0 5.7 6.7 2.3 8.5 0.4 2.3 4.2 2.8 2.3 6.9 4.1 4.4 2.8 4.0 5.3 5.5 6.5 3.9 3.7 3.9 4.2 4.4 4.1 3.5 3.9 13.7 2.1 4.9 4.6 3.7 4.1 5.7 6.6 4.8 8.7 8.0 4.9 4.9 3.8 3.1 2.6 4.2 6.3 5.9 3.2 0.5 2.3 10.8 15.7 18.7 7.7 5.2 9.5 11.0 6.6 0.4 7.2 3.1 11.0 0.0 8.7 18.4 27.8 1.9 13.7 7.4 7.6 3.2 6.3 23.8 0.0 13.6 13.8 5.7 6.4 9.2 9.3 4.5 2.1 6.1 5.7 7.4 3.3 7.1 7.6 14.2 6.1 13.2 1.5 2.8 9.1 8.8 2.8 4.3 6.6 8.2 2.5 1.3 12.7 21.8 2.2 8.6 12.7 32.3 10.3 1.5 8.0 0.0 9.3 7.0 2.7 2.5 2.6 19.9 24.9 10.5 4.7 9.3 11.7 SPATA7 "HSD3, LCA3" ENSG00000042317 "Spermatogenesis associated 7" Q9P0W8 14 88384924-88470350 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 57.0" "Group enriched" "Detected in many" 9 "Early spermatids: 946.9;Late spermatids: 1152.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038082, HPA038083" Enhanced Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Mitochondria, Cytosol" "HPA038082: AB_10671738, HPA038083: AB_10671519" "unprognostic (2.09e-2)" "unprognostic (6.72e-2)" "unprognostic (1.10e-1)" "unprognostic (6.50e-3)" "unprognostic (3.22e-2)" "unprognostic (6.75e-2)" "unprognostic (1.29e-3)" "unprognostic (4.70e-2)" "unprognostic (1.70e-1)" "unprognostic (5.45e-3)" "prognostic favorable (4.16e-5)" "unprognostic (2.88e-1)" "prognostic favorable (2.50e-5)" "unprognostic (8.41e-2)" "unprognostic (1.29e-2)" "unprognostic (6.09e-2)" "unprognostic (2.81e-2)" 5.8 6.0 8.6 1.6 10.4 1.7 6.0 28.4 9.5 7.2 6.7 5.8 2.2 6.6 7.0 2.8 8.3 5.5 5.4 8.6 10.4 9.5 5.1 4.6 1.8 8.6 9.2 12.3 7.9 7.6 11.1 2.8 8.6 6.6 3.1 10.2 4.1 4.6 5.0 5.6 3.2 4.7 8.9 3.6 5.0 57.0 9.2 3.0 12.1 4.5 1.2 5.4 4.9 11.2 2.3 3.7 5.5 7.5 8.8 16.5 6.0 5.2 9.3 5.1 3.4 1.2 4.5 2.2 2.5 5.7 3.8 2.3 2.5 4.0 4.8 3.2 1.8 0.5 1.9 2.1 12.7 3.9 0.5 7.8 6.6 2.1 3.9 16.8 9.4 5.0 1.3 2.7 4.8 2.8 2.8 3.7 1.4 2.9 4.6 3.9 5.6 1.3 8.1 1.9 3.9 4.9 5.1 6.7 5.0 6.5 6.0 4.2 4.9 3.7 4.0 5.2 2.9 2.6 2.1 1.3 6.2 1.1 2.6 0.0 1.0 0.2 2.1 1.4 2.5 1.9 1.7 1.0 2.1 0.4 1.0 1.8 0.8 0.4 0.9 2.1 0.7 1.0 8.6 10.4 28.4 9.5 8.6 10.4 8.6 9.2 8.6 8.9 9.2 11.2 7.8 12.8 7.3 38.5 1.5 2.4 7.6 9.8 7.4 10.8 6.3 8.5 12.0 7.2 8.8 3.7 20.9 2.6 5.3 1.1 9.8 11.0 946.9 22.3 13.2 6.8 16.3 1.3 113.0 7.2 3.6 11.8 4.1 4.2 1.3 19.4 7.9 4.5 5.7 15.2 91.6 4.0 12.2 17.2 2.8 1152.6 20.5 6.7 8.8 25.3 4.0 12.5 2.1 49.8 54.7 5.6 4.3 17.0 0.9 3.0 1.4 26.0 32.7 20.5 6.6 15.0 7.9 37.5 14.7 3.0 2.0 1.1 3.3 20.5 4.5 3.3 SPATA9 "FLJ35906, NYD-SP16" ENSG00000145757 "Spermatogenesis associated 9" Q9BWV2 5 95652181-95698711 "Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "testis: 26.7" "Group enriched" "Detected in some" 18 "Early spermatids: 580.3;Late spermatids: 498.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "K-562: 1.0;THP-1: 1.1" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA010848, HPA076967" Approved Approved Mitochondria NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 74: Testis - Spermatogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 34: Spermatids - Unknown function" Mitochondria "HPA010848: AB_1857422, HPA076967: " "unprognostic (4.46e-2)" "unprognostic (4.02e-2)" "unprognostic (1.37e-1)" "unprognostic (1.22e-1)" "unprognostic (9.60e-2)" "unprognostic (5.69e-2)" "unprognostic (1.33e-2)" "unprognostic (2.08e-1)" "unprognostic (3.27e-2)" "unprognostic (7.58e-2)" "unprognostic (1.28e-2)" "unprognostic (3.08e-2)" "unprognostic (9.49e-13)" "unprognostic (3.39e-1)" "unprognostic (2.37e-1)" "unprognostic (1.26e-2)" "unprognostic (2.87e-2)" 1.1 0.3 0.1 0.1 0.2 0.2 0.2 0.4 0.3 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.0 0.2 0.2 0.2 0.4 0.3 0.0 0.0 0.2 0.2 0.1 0.1 0.1 0.2 0.0 0.1 0.4 0.1 0.0 0.1 0.2 0.0 26.7 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.8 0.0 0.0 0.0 0.1 0.2 0.7 0.0 0.0 0.1 0.1 0.2 0.3 0.0 0.1 0.0 0.3 0.1 0.2 1.0 0.0 0.5 0.0 0.2 0.7 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.0 1.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.4 0.3 0.1 0.3 0.2 0.2 0.2 0.1 0.2 0.6 0.0 0.0 0.0 3.6 0.0 0.0 0.1 0.1 0.0 0.4 0.4 0.0 0.4 0.0 0.1 0.0 0.0 0.9 0.3 0.0 0.0 0.1 580.3 0.3 0.5 0.2 0.0 0.0 1.9 0.0 29.2 0.4 0.0 0.2 0.0 0.9 0.0 0.1 1.3 1.7 2.6 0.1 0.0 0.3 0.0 498.7 3.7 0.2 0.0 3.7 0.1 0.5 2.1 14.1 1.7 0.0 0.4 3.4 0.1 0.3 0.1 0.0 0.2 0.4 0.0 1.7 0.3 7.7 3.2 0.0 0.1 4.2 0.1 0.6 0.2 0.2 SPSB3 "C16orf31, SSB-3" ENSG00000162032 "SplA/ryanodine receptor domain and SOCS box containing 3" Q6PJ21 16 1776712-1793700 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046602 Uncertain Approved Mitochondria NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA046602: AB_2679717" "unprognostic (1.18e-1)" "unprognostic (2.37e-2)" "unprognostic (1.79e-1)" "unprognostic (1.15e-3)" "unprognostic (1.82e-1)" "unprognostic (8.91e-4)" "unprognostic (1.07e-2)" "unprognostic (8.31e-2)" "unprognostic (5.65e-2)" "unprognostic (8.43e-2)" "unprognostic (3.41e-2)" "unprognostic (4.83e-2)" "unprognostic (5.25e-7)" "unprognostic (2.16e-2)" "unprognostic (2.02e-1)" "unprognostic (3.77e-1)" "unprognostic (4.72e-4)" 27.1 44.7 27.9 7.7 28.5 21.2 25.8 37.0 40.2 27.1 24.0 28.9 14.7 21.3 3.3 36.1 23.7 10.0 28.6 26.4 27.2 24.3 41.8 20.6 12.4 29.7 28.3 37.1 44.0 11.4 15.3 10.3 27.4 23.3 5.1 9.6 26.4 15.5 88.5 48.4 18.8 5.6 28.3 23.3 27.8 17.3 29.2 26.1 19.7 31.0 7.8 23.2 28.7 31.8 7.3 9.1 9.7 13.4 13.6 12.5 19.8 10.6 11.0 11.5 12.6 8.4 20.0 3.2 17.4 6.0 4.5 13.9 4.8 10.9 1.8 14.7 15.0 5.2 13.9 10.4 20.2 4.5 12.0 11.3 26.8 7.2 8.4 17.1 17.5 22.1 7.8 15.4 5.4 24.0 16.3 16.0 8.1 10.8 7.1 29.7 5.9 26.7 10.6 1.3 12.9 16.6 12.6 27.8 29.4 6.9 16.1 18.0 16.1 5.6 10.6 10.5 5.5 26.1 28.2 8.9 5.4 8.9 5.9 112.3 44.8 83.4 67.9 41.8 81.2 46.8 63.1 61.7 42.3 44.2 43.6 46.6 91.5 45.7 37.2 42.8 100.7 48.4 27.9 28.5 37.0 40.2 26.4 27.2 29.7 28.3 27.4 28.3 29.2 31.8 74.2 38.5 32.1 29.7 56.1 98.4 53.3 72.7 60.3 74.1 64.1 83.7 0.2 40.0 54.9 55.2 39.6 63.0 104.2 68.6 52.8 50.8 46.7 29.4 32.3 46.1 48.7 50.5 18.2 47.6 74.8 42.8 65.2 37.8 35.4 76.2 57.1 62.5 31.8 90.9 19.4 57.8 38.7 42.7 72.2 91.6 77.0 44.8 76.5 24.4 61.6 76.0 99.9 24.6 30.7 45.3 83.2 74.9 61.2 50.5 96.3 50.6 37.2 89.8 39.5 34.0 45.3 23.8 39.7 37.0 128.3 64.4 87.8 33.2 52.7 54.3 SRBD1 FLJ10379 ENSG00000068784 "S1 RNA binding domain 1" Q8N5C6 2 45388680-45612165 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 51.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030567, HPA030568" Approved Approved Mitochondria,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Mitochondria, Cytosol" "HPA030567: AB_10611244, HPA030568: AB_10601856" "unprognostic (1.16e-2)" "unprognostic (1.27e-1)" "unprognostic (4.97e-3)" "unprognostic (2.46e-1)" "unprognostic (8.20e-3)" "unprognostic (4.14e-1)" "unprognostic (8.69e-3)" "unprognostic (9.74e-2)" "unprognostic (7.11e-2)" "unprognostic (9.36e-2)" "unprognostic (1.66e-1)" "unprognostic (2.76e-1)" "unprognostic (3.42e-3)" "unprognostic (3.99e-1)" "unprognostic (1.65e-1)" "unprognostic (1.01e-2)" "unprognostic (2.29e-1)" 6.8 5.6 1.9 7.2 2.5 6.5 7.6 2.1 1.9 9.8 3.5 7.1 5.7 7.2 11.8 4.7 5.4 5.6 5.8 1.7 2.5 7.6 8.7 6.5 7.5 2.5 2.3 5.4 7.3 12.2 3.7 6.8 2.8 7.4 8.0 3.7 5.2 5.7 3.1 3.8 5.4 6.8 2.4 8.6 8.1 9.0 2.5 11.5 10.2 4.9 7.5 5.3 3.9 2.8 18.7 9.5 19.1 12.9 6.9 15.0 15.1 14.1 12.2 13.2 12.1 8.0 7.8 16.1 10.2 10.1 9.8 8.7 19.0 17.9 24.3 22.1 10.6 21.4 7.4 17.3 8.1 17.9 12.1 9.3 7.2 15.7 18.2 5.8 16.2 5.8 15.6 11.9 19.8 17.0 24.3 13.8 21.9 12.0 10.3 16.5 27.5 14.7 15.0 12.1 16.8 13.7 12.3 13.1 14.0 9.9 8.2 6.4 14.9 18.4 14.7 9.0 12.3 12.5 4.9 9.6 10.4 17.6 13.5 3.9 6.2 13.1 5.4 7.0 4.8 5.3 4.0 6.3 6.1 4.6 5.4 5.0 2.3 8.3 12.3 5.7 4.5 4.3 1.9 2.5 2.1 1.9 1.7 2.5 2.5 2.3 2.8 2.4 2.5 2.8 10.9 19.2 7.7 28.7 13.0 3.6 3.5 6.2 8.6 7.9 8.7 8.0 8.8 8.6 10.6 3.7 4.2 8.4 15.7 5.9 9.8 8.3 3.5 11.5 20.7 9.3 7.2 15.8 22.0 9.1 7.1 10.9 20.9 9.9 8.2 11.0 7.9 13.8 9.6 13.5 32.7 9.7 0.0 22.5 3.9 2.5 7.5 13.8 7.2 46.9 13.7 12.9 13.4 48.2 51.8 4.6 6.3 6.4 19.8 2.9 5.9 10.8 7.8 14.7 13.1 12.9 10.2 37.5 28.4 9.5 3.8 5.6 12.8 16.6 5.1 2.2 SS18L2 KIAA-iso ENSG00000008324 "SS18 like 2" Q9UHA2 3 42581840-42596934 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047377 Uncertain Approved Nucleoplasm,Nucleoli,Mitochondria Yes No "Cluster 13: T-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Nucleoli, Mitochondria" Nucleoplasm "HPA047377: AB_2680020" "unprognostic (4.09e-3)" "unprognostic (1.90e-3)" "unprognostic (1.54e-1)" "unprognostic (1.19e-1)" "unprognostic (2.36e-1)" "unprognostic (1.57e-1)" "unprognostic (1.64e-2)" "prognostic favorable (7.03e-4)" "unprognostic (6.55e-2)" "unprognostic (4.51e-2)" "unprognostic (2.62e-2)" "unprognostic (2.94e-2)" "unprognostic (1.09e-3)" "unprognostic (1.44e-1)" "unprognostic (1.09e-1)" "unprognostic (1.96e-1)" "unprognostic (2.24e-3)" 21.0 17.1 27.6 18.5 28.6 33.9 21.9 28.8 37.1 19.8 26.7 17.5 19.0 12.6 17.8 21.2 15.7 10.4 18.7 28.2 28.4 24.5 32.4 19.6 35.4 28.2 27.8 19.1 21.6 13.5 25.1 9.9 28.3 35.9 13.6 13.7 19.1 8.6 16.2 24.9 25.6 7.4 28.4 31.6 22.7 10.1 27.8 23.6 20.4 11.0 30.2 19.4 18.5 31.5 32.3 14.0 29.0 26.4 34.9 27.8 17.3 20.6 22.4 28.7 32.2 27.1 29.1 43.3 18.2 13.6 31.6 17.9 33.9 28.0 30.9 21.7 40.5 46.9 28.9 45.3 25.4 62.5 36.2 22.1 17.7 23.7 21.9 20.6 31.4 39.1 43.2 65.4 23.1 29.3 44.8 76.4 45.9 42.7 34.2 23.6 20.6 61.2 32.3 38.2 16.2 23.0 17.6 27.2 29.8 30.2 35.8 57.4 19.5 18.0 29.0 42.8 38.0 46.5 76.3 73.5 26.3 66.1 17.0 60.4 56.4 84.9 88.4 66.0 121.0 120.3 116.3 106.2 62.1 104.3 99.5 101.1 75.8 83.0 50.9 74.5 139.2 90.4 27.6 28.6 28.8 37.1 28.2 28.4 28.2 27.8 28.3 28.4 27.8 31.5 39.3 12.8 16.7 5.5 96.3 107.1 70.1 101.5 91.0 16.2 78.6 77.8 19.3 42.9 46.1 27.6 8.4 57.1 102.9 39.2 56.7 43.4 4.3 47.0 37.9 37.0 55.1 67.3 13.6 49.2 75.8 39.0 39.8 71.9 45.7 39.6 32.5 61.0 66.8 23.5 11.2 51.1 79.3 38.6 51.2 3.7 34.5 43.0 51.6 6.5 69.3 38.1 88.6 3.0 25.8 50.6 58.9 15.8 72.4 75.6 121.4 85.2 28.2 26.8 13.1 26.4 32.5 19.4 24.7 84.5 138.1 37.4 103.2 34.5 53.7 99.2 STARD7 GTT1 ENSG00000084090 "StAR related lipid transfer domain containing 7" Q9NQZ5 2 96184859-96208827 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033965, HPA064958, HPA064978" Supported Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "CAB033965: AB_2302780, HPA064958: AB_2685391, HPA064978: AB_2685397" "unprognostic (3.75e-2)" "unprognostic (1.54e-2)" "unprognostic (1.67e-1)" "prognostic unfavorable (8.56e-5)" "prognostic favorable (3.89e-6)" "unprognostic (1.51e-1)" "prognostic unfavorable (2.22e-4)" "unprognostic (2.72e-3)" "unprognostic (2.38e-1)" "unprognostic (2.93e-1)" "unprognostic (4.66e-2)" "unprognostic (1.78e-1)" "prognostic favorable (4.38e-6)" "unprognostic (1.02e-1)" "unprognostic (2.04e-1)" "unprognostic (2.64e-2)" "unprognostic (2.42e-2)" 44.7 54.3 57.8 46.7 62.4 34.3 43.9 61.9 53.2 33.9 60.6 57.6 55.7 29.8 30.5 36.8 44.0 29.1 98.5 49.8 61.4 80.3 62.8 61.1 70.6 56.4 55.5 29.4 42.2 69.7 23.6 29.3 54.9 39.0 56.2 54.4 65.2 45.7 202.5 35.2 45.4 37.6 60.5 53.1 44.6 21.1 66.9 56.2 56.6 174.0 86.9 42.1 27.0 74.4 128.8 79.1 102.3 106.2 134.9 66.9 150.1 122.6 107.0 121.2 129.6 188.8 117.7 228.7 129.0 98.6 95.8 102.3 183.3 106.4 157.3 147.2 131.9 204.1 74.3 218.3 62.2 158.1 106.9 65.4 77.9 101.0 99.1 77.2 123.2 92.6 211.1 89.2 108.8 113.0 175.9 161.0 173.3 110.3 115.2 171.6 156.4 227.1 73.2 162.2 191.6 90.5 62.5 201.8 115.8 126.0 60.5 171.6 103.8 100.1 100.4 112.0 125.8 113.9 114.0 201.7 92.8 174.9 112.6 35.6 25.4 22.7 25.6 30.2 26.1 42.6 21.5 26.6 36.2 37.8 23.6 23.4 3.0 30.8 19.9 42.2 41.5 26.0 57.8 62.4 61.9 53.2 49.8 61.4 56.4 55.5 54.9 60.5 66.9 74.4 32.0 134.6 44.2 21.5 71.2 63.7 43.2 34.3 101.9 39.5 58.1 50.2 176.9 55.8 47.1 46.0 108.4 35.8 83.8 63.3 74.3 32.4 2.5 34.5 43.2 49.9 44.4 48.6 25.6 38.0 40.3 31.3 37.8 48.6 15.8 45.4 41.7 114.7 71.0 40.4 23.8 58.4 24.4 122.4 102.3 6.9 23.3 54.4 42.7 20.6 95.8 38.4 30.9 19.1 42.6 35.8 26.6 25.2 120.6 68.4 50.1 65.7 31.8 58.1 26.3 43.5 43.0 22.7 35.1 75.4 57.4 35.4 62.9 36.8 81.9 38.8 STMP1 "C7orf73, Mm47, PL-5283" ENSG00000243317 "Short transmembrane mitochondrial protein 1" E0CX11 7 135662496-135693418 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 249.0;Distal tubular cells: 197.6;Extravillous trophoblasts: 261.3;Hofbauer cells: 185.2;Proximal tubular cells: 209.5;Syncytiotrophoblasts: 275.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 431.7;eosinophil: 127.7" "Lineage enriched" "Detected in all" 6 "granulocytes: 431.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065565 Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA065565: AB_2685512" "unprognostic (3.94e-2)" "unprognostic (1.05e-1)" "unprognostic (8.76e-2)" "unprognostic (3.11e-2)" "unprognostic (3.64e-2)" "unprognostic (1.81e-1)" "unprognostic (2.99e-3)" "unprognostic (1.12e-1)" "unprognostic (4.43e-3)" "prognostic favorable (2.95e-4)" "unprognostic (1.93e-1)" "unprognostic (1.30e-1)" "unprognostic (7.21e-3)" "unprognostic (4.90e-2)" "unprognostic (9.99e-2)" "unprognostic (9.62e-3)" "unprognostic (6.81e-2)" 15.7 28.5 15.5 17.7 17.3 41.3 22.9 15.8 20.5 21.1 17.9 19.8 18.2 16.1 25.7 46.7 15.9 16.6 25.4 15.2 17.2 27.9 32.0 15.2 21.2 17.6 16.4 12.9 15.1 18.5 19.0 19.8 18.1 20.3 22.5 19.2 21.0 15.0 48.4 21.5 19.2 16.4 16.9 14.7 20.4 23.8 16.6 28.8 32.2 32.8 26.2 20.0 27.4 17.6 41.5 19.4 44.9 42.4 52.6 73.2 27.3 44.8 43.5 36.3 37.8 12.0 45.2 38.3 39.3 68.7 35.6 17.0 43.9 57.0 48.9 48.2 36.1 59.4 20.4 28.8 51.7 61.3 36.8 46.0 63.6 43.6 40.4 54.9 30.5 48.5 65.3 33.0 80.9 54.0 87.6 69.5 88.6 57.4 48.5 43.6 48.0 63.0 102.2 21.5 56.6 54.7 60.8 41.3 43.9 43.1 16.9 66.0 51.1 35.3 29.0 63.5 63.2 38.1 58.5 72.9 109.1 63.1 65.9 431.7 57.3 127.7 23.8 61.2 22.8 24.9 22.5 24.3 61.0 21.0 21.0 24.1 44.6 38.9 68.1 34.5 33.1 50.9 15.5 17.3 15.8 20.5 15.2 17.2 17.6 16.4 18.1 16.9 16.6 17.6 67.4 41.7 47.0 0.0 20.7 0.0 0.0 0.0 0.0 0.0 128.9 145.3 0.0 0.0 27.9 97.5 0.0 249.0 57.2 0.0 197.6 164.3 0.0 102.2 97.3 39.4 0.0 0.0 0.0 97.4 261.3 43.9 0.0 90.8 56.8 80.1 0.0 0.0 185.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 64.7 0.0 0.0 146.8 0.0 0.0 0.0 0.0 131.8 0.0 0.0 6.4 0.0 0.0 209.5 34.2 0.0 0.0 0.0 53.0 0.0 0.0 0.0 0.0 275.4 29.8 65.8 0.0 0.0 SUCLG1 ENSG00000163541 "Succinate-CoA ligase GDP/ADP-forming subunit alpha" P53597 2 84423528-84460045 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Ligase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 554.0" "Cell type enhanced" "Detected in all" "Distal tubular cells: 935.2;Proximal enterocytes: 647.5;Proximal tubular cells: 2949.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036683, HPA036684" Enhanced Approved "Plasma membrane,Mitochondria,Cytosol" "Intracellular and membrane" NA NA 350000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "Plasma membrane, Cytosol" "HPA036683: AB_10671708, HPA036684: AB_2675248" "unprognostic (6.84e-3)" "unprognostic (7.16e-3)" "unprognostic (2.58e-3)" "prognostic unfavorable (5.23e-4)" "unprognostic (1.02e-1)" "unprognostic (2.11e-1)" "unprognostic (3.63e-2)" "unprognostic (3.49e-2)" "unprognostic (1.02e-1)" "unprognostic (2.00e-1)" "unprognostic (2.36e-2)" "unprognostic (9.24e-2)" "prognostic favorable (2.21e-8)" "unprognostic (4.94e-2)" "unprognostic (2.08e-1)" "unprognostic (2.81e-2)" "unprognostic (1.23e-1)" 118.7 73.3 70.6 43.1 73.2 48.2 80.0 76.2 92.5 49.9 91.1 156.9 231.1 42.4 78.8 86.9 54.6 41.9 258.1 71.1 74.5 554.0 193.0 41.6 47.8 71.7 70.2 45.7 93.6 244.2 46.8 48.8 72.9 54.3 165.9 38.4 120.6 66.6 274.1 55.4 195.4 63.5 73.8 39.6 81.1 36.9 73.3 61.7 97.6 368.1 63.1 66.4 58.5 76.9 90.2 94.9 73.8 91.1 137.8 91.2 127.7 98.4 85.2 126.0 91.2 224.5 72.0 122.4 67.0 119.8 100.2 126.8 156.7 118.4 149.8 119.3 141.4 105.9 75.4 129.2 116.0 110.6 82.7 109.1 95.6 106.3 143.7 76.7 115.1 97.9 110.1 98.1 117.5 137.4 158.2 101.1 39.4 334.1 170.0 98.3 172.6 134.5 172.2 106.4 89.8 49.3 78.9 163.7 162.3 69.0 99.8 85.4 93.1 96.6 94.6 119.9 124.9 84.2 131.0 107.8 113.9 150.4 88.0 101.6 91.0 80.8 79.0 110.2 88.5 70.2 72.0 88.4 115.4 55.4 79.1 84.3 49.7 102.3 114.3 63.2 107.7 142.7 70.6 73.2 76.2 92.5 71.1 74.5 71.7 70.2 72.9 73.8 73.3 76.9 52.7 64.1 96.5 32.7 61.0 35.4 108.9 129.6 44.3 33.3 105.0 109.1 408.6 131.5 115.2 141.6 22.9 232.3 49.9 218.1 935.2 131.8 49.2 67.1 56.9 57.0 106.3 68.4 45.8 113.2 129.3 69.8 79.5 80.8 91.3 46.0 57.5 210.0 131.7 45.4 43.5 202.1 105.8 71.3 46.0 35.9 54.7 82.2 119.2 16.9 89.8 68.2 58.7 28.1 46.2 67.1 215.4 74.1 57.1 64.2 647.5 2949.2 83.7 36.1 52.6 61.1 98.3 138.9 54.4 111.3 41.3 188.4 64.4 90.7 388.7 111.0 SUCLG2 ENSG00000172340 "Succinate-CoA ligase GDP-forming subunit beta" Q96I99 3 67360460-67654612 "Citric acid cycle related proteins, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 278.0" "Cell type enhanced" "Detected in all" "Hepatocytes: 402.3;Proximal tubular cells: 354.4;Undifferentiated cells: 306.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046705, HPA051998" Enhanced Approved "Plasma membrane,Mitochondria" NA NA 300000 "Cluster 15: NK-cells - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "Plasma membrane" "HPA046705: AB_2679762, HPA051998: AB_2681687" "unprognostic (1.69e-1)" "unprognostic (2.31e-1)" "prognostic favorable (1.08e-4)" "unprognostic (2.12e-1)" "unprognostic (3.10e-1)" "unprognostic (5.32e-2)" "unprognostic (1.87e-2)" "unprognostic (1.69e-1)" "unprognostic (3.88e-1)" "unprognostic (3.26e-2)" "unprognostic (4.61e-3)" "unprognostic (5.59e-2)" "prognostic favorable (2.79e-10)" "unprognostic (3.08e-2)" "unprognostic (2.79e-1)" "unprognostic (1.07e-1)" "unprognostic (1.38e-1)" 66.7 44.9 16.1 36.7 17.9 18.6 48.7 17.1 19.6 42.1 22.4 169.7 136.6 32.6 32.2 50.5 39.1 48.4 85.5 14.2 17.6 147.3 278.0 34.0 39.3 19.0 17.3 39.0 47.8 34.6 10.2 28.1 19.5 49.3 146.1 7.3 46.8 42.3 154.0 26.1 132.2 40.0 17.7 44.8 110.6 10.4 18.1 24.7 49.3 130.6 35.5 39.3 24.0 18.8 43.8 37.4 36.3 44.6 59.7 102.5 44.2 51.3 74.4 58.9 65.4 41.7 95.1 55.7 16.3 72.5 38.8 22.0 28.5 70.8 75.9 23.8 19.5 50.5 31.2 65.5 76.8 67.2 33.9 77.3 60.3 46.2 105.2 73.0 63.6 41.8 39.1 49.5 129.9 30.6 25.5 21.2 34.1 199.2 23.0 17.6 56.1 83.8 100.0 66.9 7.1 24.5 81.5 92.7 68.8 24.3 71.6 42.5 55.9 58.2 38.2 64.5 61.8 33.4 52.2 39.0 85.5 51.6 70.0 17.3 36.3 13.0 30.8 44.3 37.6 45.5 44.6 39.5 24.6 42.5 68.4 53.1 1.6 68.0 37.4 9.8 45.4 48.5 16.1 17.9 17.1 19.6 14.2 17.6 19.0 17.3 19.5 17.7 18.1 18.8 40.2 35.3 50.8 66.6 48.5 37.1 44.7 38.9 21.1 2.9 54.1 29.1 172.0 84.4 51.7 80.9 8.4 55.4 31.7 223.5 244.6 85.1 3.2 49.6 43.4 40.1 58.2 17.2 6.2 80.9 44.9 47.5 90.7 46.8 30.4 31.4 45.0 402.3 56.5 5.0 5.3 212.1 40.7 68.6 49.2 5.4 41.3 36.3 42.7 90.9 35.5 29.2 36.0 72.4 60.0 59.2 164.0 47.4 30.3 41.2 222.2 354.4 58.7 4.5 32.9 41.6 50.5 1.6 6.3 55.6 49.3 38.0 48.6 78.5 306.6 50.9 SYNJ2BP Arip2 ENSG00000213463 "Synaptojanin 2 binding protein" P57105 14 70366499-70417090 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 140.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA000866 Approved Supported Approved Mitochondria NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 8: Non-specific - Mitochondria" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 44: Endometrium - Transcription" Mitochondria "HPA000866: AB_2276678" "unprognostic (2.68e-1)" "unprognostic (1.76e-1)" "unprognostic (2.67e-1)" "unprognostic (3.31e-1)" "unprognostic (1.28e-1)" "unprognostic (1.04e-1)" "unprognostic (1.65e-1)" "unprognostic (1.60e-2)" "unprognostic (5.70e-2)" "unprognostic (6.14e-2)" "unprognostic (6.35e-3)" "unprognostic (1.44e-2)" "prognostic favorable (1.11e-16)" "unprognostic (2.81e-1)" "unprognostic (1.38e-1)" "unprognostic (5.35e-3)" "unprognostic (1.14e-2)" 10.2 10.1 10.3 7.3 10.1 1.3 9.9 9.3 10.0 8.1 13.3 13.7 19.6 9.0 7.9 8.2 7.2 8.4 14.9 8.4 9.3 21.7 20.3 9.5 6.6 10.0 9.8 7.2 7.4 24.9 6.6 9.3 9.8 12.9 15.1 16.4 9.5 11.9 28.7 5.7 16.0 10.7 10.8 9.1 15.5 3.9 10.6 5.1 11.2 29.3 6.4 8.6 6.1 9.7 14.0 9.1 15.3 10.3 11.7 13.4 10.6 10.8 11.1 7.4 8.3 8.7 12.8 0.0 10.0 12.7 7.5 11.6 15.7 11.6 17.5 1.9 8.0 5.2 13.9 11.4 10.3 0.0 1.7 10.5 9.2 9.4 5.3 13.1 16.6 5.8 3.1 2.7 13.4 10.2 7.2 2.1 11.1 13.9 10.9 9.0 22.4 3.9 16.0 20.7 11.1 19.4 14.6 12.0 8.8 9.9 22.7 3.6 18.5 17.7 12.1 6.9 8.7 3.7 15.0 0.0 15.6 1.8 14.9 0.3 3.0 0.1 2.3 3.1 2.7 2.5 2.8 2.7 3.0 2.0 3.8 3.1 0.3 2.3 2.1 1.9 2.3 1.1 10.3 10.1 9.3 10.0 8.4 9.3 10.0 9.8 9.8 10.8 10.6 9.7 36.6 38.5 46.6 0.0 17.8 6.0 28.7 49.4 9.1 44.9 25.9 15.4 89.4 48.6 43.3 75.4 81.3 38.3 13.1 50.1 140.8 49.0 36.9 56.0 26.5 38.4 19.8 5.7 0.0 39.2 31.5 21.7 21.9 85.7 9.5 33.5 37.1 50.4 24.7 30.3 0.0 41.2 44.7 23.6 9.1 9.8 30.4 16.9 14.2 0.0 28.8 37.1 28.8 0.0 0.0 35.7 43.5 41.3 4.2 25.8 87.3 77.0 31.5 88.0 26.3 37.6 27.8 68.9 12.9 12.5 4.8 10.9 17.4 25.0 62.6 30.3 SYNJ2BP-COX16 ENSG00000258644 "SYNJ2BP-COX16 readthrough" 14 70326064-70417074 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 11.3" "Cell type enhanced" "Detected in some" "Erythroid cells: 4.8;Excitatory neurons: 3.1;Inhibitory neurons: 2.7" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 10.1;U-2 OS: 10.6" "Low region specificity" "Detected in all" "HPA000866, HPA062659" Approved Supported Approved Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA000866: AB_2276678, HPA062659: AB_2684823" "unprognostic (9.44e-2)" "unprognostic (2.42e-1)" "unprognostic (4.33e-2)" "unprognostic (1.68e-2)" "unprognostic (1.06e-1)" "unprognostic (1.34e-1)" "unprognostic (8.70e-2)" "unprognostic (2.02e-1)" "unprognostic (1.96e-2)" "unprognostic (3.00e-1)" "unprognostic (2.21e-2)" "unprognostic (6.41e-2)" "unprognostic (6.73e-4)" "unprognostic (6.68e-2)" "unprognostic (6.93e-2)" "unprognostic (2.55e-1)" "unprognostic (2.12e-2)" 2.7 2.8 0.4 1.4 0.6 0.4 2.2 0.7 2.5 2.6 0.5 2.9 1.1 2.6 0.8 1.8 1.8 0.8 4.3 0.5 0.7 3.6 2.3 2.1 1.7 0.6 0.5 2.8 0.7 1.3 1.7 1.0 0.6 1.9 0.7 0.7 1.2 0.5 3.1 1.3 1.3 1.5 0.5 1.9 2.1 11.3 0.5 2.4 1.7 2.4 1.1 2.5 1.8 0.5 5.9 1.6 3.4 1.2 0.0 0.2 2.3 6.2 0.5 2.7 2.4 0.6 7.4 0.0 4.6 0.0 4.9 4.7 0.0 1.1 2.0 0.7 2.0 0.0 1.0 2.5 2.6 0.0 1.2 0.0 1.4 2.3 0.0 4.2 1.9 4.7 0.0 0.5 1.6 0.4 3.6 1.1 1.6 10.1 1.8 4.7 0.7 2.9 1.4 2.3 2.9 4.7 1.1 2.2 3.5 4.2 2.2 2.9 0.0 2.9 10.6 0.0 3.2 0.3 2.6 0.0 5.3 0.0 4.0 1.6 8.9 0.1 11.1 11.2 11.5 14.4 12.1 11.0 12.0 13.6 11.4 10.8 0.0 15.1 5.7 9.2 12.8 7.9 0.4 0.6 0.7 2.5 0.5 0.7 0.6 0.5 0.6 0.5 0.5 0.5 0.6 0.0 0.5 1.0 1.1 0.0 0.1 0.0 1.2 0.3 0.4 0.1 0.0 0.0 0.6 0.0 0.0 0.3 1.4 0.0 1.9 0.4 1.6 2.0 0.7 1.8 0.0 4.8 3.1 0.8 0.4 1.1 1.1 2.6 0.0 0.3 0.7 0.7 0.2 0.0 2.7 0.0 0.0 0.8 0.0 0.9 0.6 1.0 0.0 0.0 0.1 0.3 2.1 0.5 0.6 0.3 0.1 0.4 2.4 0.0 0.2 0.6 0.0 0.3 0.0 0.2 0.9 1.0 0.2 1.5 0.0 0.3 0.6 0.2 0.4 0.0 TAGLN "DKFZp686P11128, SM22, SMCC, TAGLN1, WS3-10" ENSG00000149591 Transgelin Q01995 11 117199370-117207464 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 9628.1;intestine: 11712.2" "Group enriched" "Detected in many" 4 "Breast myoepithelial cells: 2508.6;Peritubular cells: 2306.4;Sertoli cells: 2866.2;Smooth muscle cells: 4563.9" "Cancer enhanced" "Detected in all" "prostate cancer: 279.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "intermediate monocyte: 41.6;non-classical monocyte: 63.1" "Lineage enriched" "Detected in many" 12 "monocytes: 63.1" "Cell line enhanced" "Detected in all" "BJ: 1913.4;BJ hTERT+ SV40 Large T+: 1641.8;CACO-2: 1531.4;EFO-21: 2145.6;fHDF/TERT166: 2094.4;hTERT-RPE1: 1499.7;LHCN-M2: 1377.1;U-138 MG: 1598.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001447, HPA019467" Enhanced Approved Microtubules,Mitochondria,Cytosol No No 6300000 "Cluster 51: Monocytes - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Microtubules, Mitochondria" Cytosol "CAB001447: AB_564012, HPA019467: AB_1857245" "unprognostic (1.36e-2)" "unprognostic (1.06e-1)" "unprognostic (3.57e-3)" "unprognostic (1.91e-1)" "unprognostic (6.58e-2)" "unprognostic (1.02e-2)" "unprognostic (2.39e-2)" "unprognostic (7.16e-2)" "unprognostic (2.35e-2)" "unprognostic (1.24e-1)" "unprognostic (4.43e-2)" "unprognostic (1.76e-1)" "prognostic unfavorable (2.12e-7)" "unprognostic (9.58e-3)" "unprognostic (3.03e-1)" "unprognostic (1.10e-1)" "unprognostic (2.52e-3)" 2235.7 512.7 118.5 963.9 144.4 12.1 1680.5 126.1 215.9 3611.3 172.5 11712.2 451.2 9628.1 693.9 1954.6 4610.6 893.8 1583.5 119.6 120.4 774.5 302.8 1258.6 245.5 137.0 127.0 1643.4 218.6 65.3 254.6 348.0 129.2 4624.1 1154.6 22.9 461.8 6383.6 356.4 619.8 1948.4 7108.7 127.2 532.0 3148.4 202.5 138.2 52.2 723.2 152.4 59.9 5521.7 2331.2 130.0 17.5 5.5 293.3 8.2 140.0 123.8 226.7 1913.4 788.1 1641.8 609.0 1531.4 28.4 3.2 2145.6 2094.4 1.7 46.1 4.4 16.8 543.3 6.8 4.4 5.0 66.9 130.2 708.7 1.7 5.2 304.6 57.5 267.1 36.1 1499.7 3.3 4.5 3.3 6.7 1377.1 4.5 1.7 15.8 84.6 18.8 2.1 2.7 23.1 12.0 4.4 25.8 1.9 9.6 29.9 11.0 1.5 807.6 9.2 5.1 182.0 1598.8 276.9 14.4 86.6 8.9 8.8 21.7 9.1 7.7 6.2 1.8 2.7 0.1 0.3 41.6 0.5 3.6 0.1 0.0 3.2 5.1 0.2 0.1 0.3 0.0 63.1 1.6 0.5 2.1 118.5 144.4 126.1 215.9 119.6 120.4 137.0 127.0 129.2 127.2 138.2 130.0 264.8 38.5 6.1 4.6 10.3 63.9 453.4 248.6 10.8 9.9 74.0 2508.6 1.3 4.3 22.5 40.5 18.8 57.0 8.6 3.1 0.0 577.8 3.3 14.6 455.5 260.3 3.0 2.7 4.5 74.5 35.3 464.4 41.3 12.8 1.3 32.4 639.7 8.9 41.5 1.7 6.5 18.3 24.4 23.1 91.8 23.9 48.4 33.8 96.0 37.5 8.1 4.9 2.1 3.0 11.9 38.4 4.5 2306.4 3.2 414.0 12.1 2.2 23.0 9.9 2866.2 177.6 4563.9 6.0 13.7 8.6 60.9 32.2 15.1 8.3 3.1 62.0 TBC1D32 "bA57L9.1, BROMI, C6orf170, C6orf171, dJ310J6.1, FLJ30899, FLJ34235" ENSG00000146350 "TBC1 domain family member 32" Q96NH3 6 121079494-121334745 "Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 7.4" "Cell type enhanced" "Detected in many" "Astrocytes: 68.2;Excitatory neurons: 124.1;Inhibitory neurons: 87.4;Oligodendrocyte precursor cells: 105.6;Oligodendrocytes: 102.6;Rod photoreceptor cells: 110.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 22.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013413 Uncertain Approved Mitochondria NA NA "Cluster 6: Non-specific - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 44: HDLM-2 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" Mitochondria "HPA013413: AB_10602702" "unprognostic (3.31e-2)" "unprognostic (1.28e-1)" "unprognostic (9.12e-3)" "unprognostic (4.82e-2)" "unprognostic (2.44e-2)" "unprognostic (1.98e-2)" "unprognostic (3.60e-4)" "unprognostic (7.28e-2)" "unprognostic (1.02e-1)" "unprognostic (1.83e-1)" "unprognostic (8.14e-2)" "unprognostic (2.01e-2)" "unprognostic (3.73e-2)" "unprognostic (1.57e-2)" "unprognostic (7.62e-2)" "unprognostic (2.17e-1)" "unprognostic (2.06e-1)" 1.2 2.4 0.8 0.9 1.5 0.8 1.7 0.6 1.4 1.8 0.9 1.1 1.8 1.7 0.8 1.0 1.6 1.9 0.7 0.8 1.6 1.4 0.4 0.9 1.0 1.1 1.4 1.8 1.3 2.3 1.5 2.9 1.2 1.6 0.7 7.4 0.8 0.9 0.2 1.2 1.4 0.8 0.6 1.0 1.3 3.6 1.8 1.6 2.4 0.5 1.1 1.0 0.9 2.5 1.7 2.0 3.4 4.4 2.8 4.5 1.8 1.9 2.9 3.2 4.6 0.1 1.3 3.4 3.2 2.0 4.7 1.5 1.6 1.6 4.0 22.7 2.2 3.9 0.7 0.7 1.2 2.1 1.5 1.7 1.2 2.8 2.1 3.8 0.7 3.9 2.2 0.0 2.5 1.0 2.3 1.3 1.9 1.1 0.7 2.1 1.6 0.3 1.6 0.8 6.5 3.5 2.2 1.4 1.0 1.8 2.1 1.6 0.4 2.1 2.1 0.6 2.2 1.6 0.0 1.3 3.0 1.1 3.3 6.1 0.9 1.3 1.8 0.5 1.3 2.5 1.4 1.3 0.7 4.5 2.6 2.0 0.8 2.6 0.9 8.2 1.6 0.3 0.8 1.5 0.6 1.4 0.8 1.6 1.1 1.4 1.2 0.6 1.8 2.5 3.9 3.2 8.4 68.2 6.4 6.1 3.7 3.1 9.6 26.2 6.1 5.0 3.1 4.3 10.1 7.3 43.8 4.4 8.7 3.4 0.0 2.4 9.8 8.8 9.5 3.5 5.4 1.7 124.1 2.2 1.7 6.2 10.2 4.7 3.8 26.7 2.9 1.1 1.4 13.5 87.4 6.0 4.1 1.6 2.9 3.5 2.5 2.8 1.8 36.5 1.5 6.7 3.1 105.6 102.6 1.0 3.9 1.9 1.8 2.3 8.0 1.5 20.3 110.4 0.0 6.6 5.3 21.5 7.9 3.4 5.1 2.3 4.9 4.8 4.8 2.3 TCIRG1 "a3, Atp6i, ATP6N1C, ATP6V0A3, OC-116, OC116, TIRC7" ENSG00000110719 "T cell immune regulator 1, ATPase H+ transporting V0 subunit a3" Q13488 11 68039025-68050895 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" "Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 289.2" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 135.5;Kupffer cells: 115.2;Macrophages: 132.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 131.9;RPMI-8226: 138.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038742 Approved Approved Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Mitochondria "HPA038742: AB_10795138" "unprognostic (5.35e-2)" "unprognostic (5.01e-2)" "unprognostic (1.81e-2)" "unprognostic (1.50e-2)" "unprognostic (6.98e-3)" "unprognostic (1.25e-1)" "unprognostic (5.07e-2)" "unprognostic (6.43e-2)" "unprognostic (7.03e-2)" "unprognostic (2.47e-2)" "unprognostic (1.36e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.50e-11)" "unprognostic (2.48e-3)" "unprognostic (7.88e-3)" "unprognostic (2.50e-1)" "prognostic favorable (9.45e-6)" 56.8 112.5 7.1 46.1 7.1 97.7 47.2 9.2 14.5 85.1 11.4 66.6 44.2 58.0 18.6 45.3 61.4 11.7 27.9 6.6 7.2 35.5 61.7 113.9 30.9 10.9 9.3 49.1 289.2 4.4 20.3 14.1 12.0 72.2 8.0 0.3 57.9 16.1 10.5 25.9 87.0 12.1 9.1 194.8 59.2 6.7 18.1 12.1 52.5 3.9 13.4 56.1 60.7 10.8 31.8 57.2 0.8 0.2 25.1 19.7 39.0 61.5 29.4 17.2 16.3 1.3 92.0 2.7 32.9 21.9 26.2 39.0 3.7 23.5 3.6 82.1 1.9 22.0 80.6 18.9 23.4 16.3 131.9 22.8 13.5 21.2 1.4 0.0 11.8 1.2 11.6 8.4 5.7 10.7 0.8 97.8 3.5 44.6 14.4 26.8 0.9 138.6 16.2 17.6 3.0 0.7 26.0 33.4 16.8 6.1 36.3 41.1 42.3 33.2 25.9 93.3 11.4 1.3 1.2 4.8 74.0 26.7 16.2 21.7 65.5 72.8 15.7 109.0 12.7 11.3 11.7 16.9 49.0 7.5 6.6 7.2 150.0 32.1 144.3 33.8 12.1 47.8 7.1 7.1 9.2 14.5 6.6 7.2 10.9 9.3 12.0 9.1 18.1 10.8 40.6 28.9 59.8 0.3 37.1 6.2 13.2 36.2 7.4 0.7 14.9 8.9 1.6 18.6 57.1 7.3 0.0 21.7 60.6 74.2 0.0 30.4 0.4 13.3 16.7 22.1 23.9 15.2 0.3 67.0 54.1 24.9 135.5 21.5 50.0 29.5 21.0 17.8 105.1 0.0 0.6 32.4 18.3 115.2 22.8 0.6 5.9 132.3 5.4 8.4 74.9 0.7 45.3 0.5 0.1 51.8 85.4 13.2 59.1 10.6 45.5 2.0 47.9 1.0 39.5 7.7 26.0 0.1 2.9 10.4 5.3 26.5 46.5 9.0 36.2 19.0 TFAP4 "AP-4, bHLHc41" ENSG00000090447 "Transcription factor AP-4" Q01664 16 4257186-4273075 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 30.1;Proximal enterocytes: 40.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001912 Supported Supported Nucleoplasm,Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 50: Non-specific - Ribosome" "Cluster 24: NB-4 - Immune response" "Cluster 32: Non-specific - Translation" "Nucleoplasm, Mitochondria" "HPA001912: AB_1080251" "unprognostic (1.61e-2)" "unprognostic (1.36e-1)" "unprognostic (5.10e-2)" "unprognostic (4.42e-3)" "unprognostic (8.61e-2)" "unprognostic (1.15e-2)" "prognostic unfavorable (3.32e-4)" "unprognostic (8.05e-2)" "unprognostic (8.97e-2)" "unprognostic (4.60e-1)" "unprognostic (5.75e-2)" "unprognostic (7.68e-2)" "prognostic unfavorable (4.31e-6)" "unprognostic (1.08e-2)" "unprognostic (3.25e-1)" "unprognostic (2.39e-2)" "unprognostic (1.30e-1)" 6.2 4.2 3.7 6.9 3.8 1.9 5.8 5.3 5.4 9.0 1.7 5.4 6.4 7.8 1.0 8.1 6.9 3.8 3.2 3.5 3.2 3.6 5.3 3.9 6.8 3.9 3.7 10.0 12.0 3.3 4.3 3.7 3.9 5.7 1.9 0.7 7.6 3.1 7.5 10.5 6.8 2.5 3.5 7.3 5.0 1.7 3.7 8.3 4.6 3.1 3.9 6.4 8.4 5.1 14.9 15.4 12.9 19.2 5.4 14.1 21.7 5.7 14.6 9.6 10.5 8.1 23.0 51.0 14.5 5.5 4.5 22.0 23.6 19.4 3.0 29.8 17.4 15.6 13.0 21.1 7.5 27.8 8.8 13.3 12.2 10.4 29.0 4.5 6.4 16.7 29.1 13.1 3.8 23.9 39.2 46.4 29.8 14.7 20.2 34.3 28.8 53.7 3.7 11.2 27.0 20.0 19.2 19.7 18.9 2.0 10.0 21.9 4.2 13.1 10.4 46.2 15.1 21.3 19.3 43.6 8.8 27.2 9.5 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 3.7 3.8 5.3 5.4 3.5 3.2 3.9 3.7 3.9 3.5 3.7 5.1 7.0 3.2 0.0 2.3 11.6 21.5 9.8 5.7 30.1 4.2 8.1 6.6 2.2 7.2 2.1 27.6 0.0 7.7 5.3 5.3 7.9 4.1 0.1 2.4 9.6 5.4 7.8 22.7 3.0 5.7 11.7 7.6 10.7 3.1 0.0 6.9 3.6 3.4 4.2 0.0 3.9 12.4 8.2 4.0 7.4 0.1 11.8 3.7 3.6 1.0 4.7 2.2 5.2 1.5 3.6 2.9 5.3 5.3 7.2 11.1 40.0 5.7 1.4 3.4 6.6 6.9 7.1 0.9 0.9 22.1 22.3 2.2 7.3 7.5 20.2 4.3 THAP9 FLJ34093 ENSG00000168152 "THAP domain containing 9" Q9H5L6 4 82900684-82919969 "Predicted intracellular proteins, Transcription factors" "DNA integration, DNA recombination" "DNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 40.5;Late spermatids: 52.9;Oligodendrocytes: 20.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA037420, HPA037421" Uncertain Approved Mitochondria No No "Cluster 7: Monocytes - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" Mitochondria "HPA037420: AB_2675467, HPA037421: AB_10673631" "unprognostic (7.54e-3)" "unprognostic (8.52e-2)" "unprognostic (4.14e-2)" "unprognostic (1.51e-2)" "unprognostic (2.06e-1)" "unprognostic (1.18e-2)" "unprognostic (2.26e-1)" "unprognostic (4.51e-2)" "unprognostic (1.17e-1)" "unprognostic (2.30e-2)" "unprognostic (2.30e-2)" "unprognostic (2.65e-2)" "prognostic favorable (3.50e-5)" "unprognostic (1.39e-1)" "unprognostic (1.62e-1)" "unprognostic (4.64e-3)" "unprognostic (8.74e-4)" 1.3 1.6 3.0 1.0 3.6 2.0 3.2 3.3 4.5 2.0 2.6 1.5 1.5 2.5 3.6 1.3 1.7 1.3 2.7 3.1 3.3 3.0 3.2 1.6 1.8 3.4 3.2 3.2 2.5 3.2 2.7 2.1 3.6 2.4 1.6 4.3 2.0 1.9 5.2 1.7 1.5 1.4 3.2 1.4 1.4 6.7 3.1 2.5 4.1 6.8 1.7 1.5 1.6 5.8 1.1 1.5 5.7 3.2 1.7 2.0 4.0 1.1 1.8 1.1 1.0 2.3 2.0 6.3 2.0 1.5 2.1 1.4 4.6 1.8 1.3 2.4 1.7 2.7 2.2 2.9 2.0 2.5 2.1 2.1 2.9 0.5 2.8 1.7 1.7 5.1 2.4 4.2 1.4 1.5 6.1 3.0 4.6 2.2 0.8 5.5 2.4 3.7 2.0 1.3 4.8 3.3 2.2 3.0 4.1 4.7 1.8 2.2 1.1 1.4 1.6 1.1 0.8 2.7 1.3 6.0 1.7 1.5 2.2 0.0 0.9 0.1 0.5 1.4 0.7 1.3 0.4 0.5 1.0 1.1 1.2 1.0 0.0 0.6 1.0 0.6 0.2 0.5 3.0 3.6 3.3 4.5 3.1 3.3 3.4 3.2 3.6 3.2 3.1 5.8 3.2 3.2 3.6 8.5 2.8 0.8 2.8 2.3 2.2 2.8 2.4 2.3 5.0 0.0 2.2 1.8 6.2 3.2 3.6 1.3 0.0 1.6 40.5 4.0 2.8 2.0 3.0 2.5 4.6 2.5 2.0 2.3 5.6 4.2 1.3 4.2 1.4 1.3 1.3 0.0 4.7 1.7 2.0 0.8 1.3 52.9 1.8 2.6 0.0 3.7 1.3 4.0 2.1 7.5 20.8 0.9 0.7 0.0 2.3 1.8 1.1 2.5 1.9 4.7 6.6 4.6 2.8 6.1 5.2 2.6 1.7 3.3 2.0 1.4 1.5 2.0 THNSL1 "FLJ22002, TSH1" ENSG00000185875 "Threonine synthase like 1" Q8IYQ7 10 25016612-25026664 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 21.4" "Cell type enhanced" "Detected in many" "Distal tubular cells: 15.6;Early spermatids: 29.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 32.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037585 Uncertain Approved "Nuclear bodies,Mitochondria,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Nuclear bodies, Cytosol" Mitochondria "HPA037585: AB_10696940" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (2.31e-1)" "unprognostic (4.31e-2)" "unprognostic (5.26e-2)" "unprognostic (6.11e-2)" "unprognostic (8.91e-2)" "unprognostic (1.05e-1)" "unprognostic (2.80e-1)" "unprognostic (9.75e-2)" "unprognostic (2.63e-2)" "unprognostic (1.52e-1)" "unprognostic (1.71e-3)" "unprognostic (2.08e-1)" "unprognostic (3.21e-2)" "unprognostic (9.84e-3)" "unprognostic (3.06e-2)" 1.7 6.0 4.0 1.8 4.2 0.6 3.6 3.2 4.5 4.1 2.9 2.7 2.6 3.6 4.9 1.9 5.6 2.0 3.7 4.1 4.2 9.7 21.4 1.5 2.8 3.9 3.5 7.3 3.0 5.3 3.7 1.7 4.2 2.9 3.0 4.1 3.4 2.6 4.6 2.2 2.4 2.2 3.9 2.2 2.7 5.9 4.1 3.3 8.3 5.9 2.7 1.8 1.5 4.3 7.1 8.1 5.0 10.0 5.0 6.2 1.3 3.4 1.3 3.7 2.4 5.3 8.8 32.7 10.6 1.6 4.0 3.8 7.2 6.4 3.8 4.5 3.9 12.0 2.2 3.4 5.6 0.0 2.0 3.9 11.6 2.7 5.7 6.4 2.5 13.3 10.4 3.8 8.0 11.1 6.6 2.3 9.2 12.3 3.9 3.5 1.3 14.2 10.6 1.6 8.3 4.7 6.8 6.0 12.3 2.6 6.0 0.6 2.5 4.4 3.9 5.9 3.2 2.7 3.8 0.0 7.3 6.6 3.5 0.1 0.4 0.0 2.9 0.5 5.1 5.0 4.1 3.8 2.2 3.8 9.5 6.3 0.6 10.8 0.7 3.7 2.0 3.1 4.0 4.2 3.2 4.5 4.1 4.2 3.9 3.5 4.2 3.9 4.1 4.3 1.3 3.2 3.2 2.6 3.4 0.6 3.1 5.6 2.8 4.2 2.1 2.9 8.5 1.5 6.1 3.7 0.0 6.1 0.8 0.6 15.6 3.3 29.9 5.1 3.9 1.8 1.2 2.5 4.0 1.3 3.9 2.7 1.5 2.5 0.0 7.8 2.2 9.8 2.1 3.3 5.1 1.8 2.0 0.9 0.8 5.5 2.1 0.6 0.0 4.7 1.5 6.8 0.0 2.0 5.4 1.1 1.0 1.5 0.9 1.8 2.3 11.0 8.7 4.5 0.0 4.3 1.9 8.2 13.6 2.6 1.0 1.0 2.8 11.8 3.5 1.1 TIMM17B "DXS9822, JM3" ENSG00000126768 "Translocase of inner mitochondrial membrane 17B" O60830 X 48893447-48898143 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029093 Approved Approved Microtubules,Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Microtubules Mitochondria "HPA029093: AB_10600913" "unprognostic (7.87e-2)" "prognostic favorable (6.63e-4)" "unprognostic (8.44e-2)" "unprognostic (3.52e-2)" "unprognostic (1.00e-1)" "unprognostic (1.28e-1)" "unprognostic (3.89e-3)" "unprognostic (1.44e-1)" "unprognostic (2.01e-1)" "unprognostic (1.14e-2)" "unprognostic (2.04e-1)" "unprognostic (2.16e-1)" "unprognostic (2.67e-2)" "unprognostic (9.40e-2)" "unprognostic (5.24e-3)" "unprognostic (8.67e-2)" "prognostic favorable (7.88e-4)" 24.0 42.0 49.8 18.8 51.1 28.2 25.9 50.6 60.6 29.2 47.0 40.3 25.5 27.7 21.0 38.2 29.1 17.6 75.3 50.1 49.6 47.5 48.7 28.1 27.8 49.5 48.9 27.3 33.4 47.6 45.1 23.0 48.9 36.4 19.4 26.2 25.3 27.7 99.1 35.4 32.2 18.0 50.5 37.9 40.5 18.7 50.6 40.7 30.4 83.2 26.8 35.5 28.7 53.1 71.0 127.8 78.7 78.1 24.2 19.3 65.4 31.3 47.7 81.1 52.9 113.3 93.4 51.8 47.4 27.2 131.1 52.5 125.1 68.3 30.4 111.2 140.1 37.6 69.2 101.4 68.3 56.5 35.0 24.9 67.3 60.9 80.8 40.3 37.6 90.1 56.5 118.2 37.8 183.5 89.4 136.7 102.8 93.2 118.3 62.1 51.0 187.8 80.9 41.1 77.6 69.7 48.6 77.0 47.0 98.5 168.7 97.4 26.2 37.1 72.4 89.8 54.9 107.8 137.1 64.3 51.4 100.3 44.6 178.2 123.4 179.9 67.2 123.9 77.4 113.4 67.1 76.3 121.1 113.4 64.8 59.7 139.6 75.7 104.8 127.6 74.4 124.3 49.8 51.1 50.6 60.6 50.1 49.6 49.5 48.9 48.9 50.5 50.6 53.1 23.8 25.6 34.9 4.9 56.5 30.2 52.4 99.0 21.1 40.4 52.9 62.2 40.0 41.5 59.4 73.5 16.7 94.4 45.0 40.2 185.9 94.5 5.6 42.4 25.5 24.6 81.5 48.8 4.3 73.1 94.3 31.0 34.1 37.8 52.0 50.3 24.7 56.0 99.6 35.3 5.6 68.3 91.6 37.6 49.8 7.4 23.9 48.9 44.4 3.7 85.9 48.7 55.6 2.5 9.1 89.9 92.7 23.0 103.7 63.3 102.4 160.0 56.6 43.8 32.9 21.2 45.0 29.0 39.9 52.0 34.4 79.6 48.2 52.7 59.8 61.2 TMCO6 "FLJ39769, PRO1580" ENSG00000113119 "Transmembrane and coiled-coil domains 6" Q96DC7 5 140639435-140645408 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037473, HPA037474" Uncertain Approved Nucleoplasm,Mitochondria No No "Cluster 14: Monocytes - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria Nucleoplasm "HPA037473: AB_10671049, HPA037474: AB_10671050" "unprognostic (1.03e-1)" "unprognostic (3.40e-1)" "unprognostic (3.95e-2)" "unprognostic (1.38e-2)" "unprognostic (6.10e-3)" "unprognostic (1.31e-2)" "unprognostic (1.65e-1)" "unprognostic (2.11e-1)" "unprognostic (4.89e-2)" "unprognostic (1.69e-1)" "unprognostic (2.75e-2)" "unprognostic (6.24e-2)" "prognostic unfavorable (6.37e-4)" "unprognostic (7.21e-2)" "unprognostic (1.77e-1)" "unprognostic (1.96e-2)" "unprognostic (1.20e-2)" 6.6 10.5 5.7 3.9 5.7 2.9 6.6 5.5 5.8 6.1 5.5 4.9 2.9 4.8 3.4 7.2 6.9 2.9 3.1 5.5 5.8 6.7 13.3 3.6 4.6 6.0 5.9 7.1 6.6 4.0 4.9 5.6 5.9 4.8 2.5 0.7 9.8 2.9 3.6 5.2 4.8 3.0 6.3 7.2 5.2 10.4 5.9 7.7 5.3 2.6 4.0 5.4 5.6 7.0 3.9 7.5 5.0 7.4 4.9 5.2 18.1 3.0 3.4 3.8 4.1 11.6 7.2 15.6 7.8 2.3 4.4 7.7 4.2 8.8 2.0 5.5 13.7 11.9 3.7 8.3 6.5 6.7 4.4 8.6 2.3 4.6 7.7 2.9 8.9 12.6 5.1 5.0 4.7 7.5 15.3 15.5 5.7 9.2 11.3 13.1 10.3 15.5 4.6 3.5 8.6 3.7 8.6 16.6 8.0 3.4 13.6 7.9 4.2 0.1 3.7 1.4 1.3 8.4 5.7 7.4 2.4 10.7 4.6 11.6 6.5 5.7 5.2 9.1 5.7 7.8 6.9 5.1 6.9 6.1 9.5 3.9 12.7 4.4 10.3 1.9 8.2 4.1 5.7 5.7 5.5 5.8 5.5 5.8 6.0 5.9 5.9 6.3 5.9 7.0 4.0 6.4 2.0 1.3 7.5 1.9 7.3 3.4 6.8 5.2 4.6 4.3 0.6 5.7 2.4 11.0 6.2 7.7 4.2 3.9 0.0 3.8 4.1 2.2 4.0 6.3 7.3 10.3 3.8 2.4 7.4 4.6 6.6 2.5 0.0 4.6 10.0 9.7 4.8 0.0 3.3 5.0 4.1 5.1 2.7 1.5 4.1 4.1 1.8 9.4 6.6 3.3 16.5 1.0 3.9 4.5 5.2 4.9 7.3 7.4 6.2 2.4 6.2 4.3 6.6 3.9 3.4 19.2 15.8 10.3 2.3 6.3 8.2 7.7 7.7 6.9 TMEM132A "FLJ20539, GBP, HSPA5BP1" ENSG00000006118 "Transmembrane protein 132A" Q24JP5 11 60924460-60937159 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 187.8;choroid plexus: 117.3" "Cell type enhanced" "Detected in many" "Astrocytes: 82.3;Ductal cells: 80.0;Horizontal cells: 254.1;Muller glia cells: 188.8;Rod photoreceptor cells: 165.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 174.1;MCF7: 177.8;SK-BR-3: 176.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051979, HPA060492" Enhanced Supported Approved Mitochondria No No 4100000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 38: EFO-21 - Unknown function" "Cluster 62: Horizontal cells - Visual perception" Mitochondria "HPA051979: AB_2681681, HPA060492: " "unprognostic (2.52e-2)" "unprognostic (2.01e-1)" "unprognostic (3.75e-2)" "prognostic favorable (1.98e-5)" "unprognostic (7.94e-3)" "unprognostic (3.74e-1)" "unprognostic (4.42e-3)" "unprognostic (2.39e-2)" "unprognostic (1.99e-1)" "unprognostic (1.30e-1)" "unprognostic (2.88e-1)" "unprognostic (5.98e-2)" "prognostic unfavorable (1.55e-9)" "unprognostic (3.31e-1)" "unprognostic (9.74e-2)" "unprognostic (1.50e-1)" "unprognostic (8.41e-3)" 7.7 21.0 137.9 8.6 134.3 0.3 7.7 119.4 187.8 12.0 117.3 5.5 2.5 13.6 1.2 19.5 4.8 5.5 13.7 134.1 136.9 13.9 2.1 10.1 1.7 154.5 131.2 18.8 6.8 12.4 23.6 16.6 126.4 9.4 1.0 28.1 25.9 1.8 3.9 6.1 6.0 3.7 123.0 5.7 32.4 6.7 144.6 1.3 4.8 3.1 5.4 4.2 9.2 114.7 37.0 50.7 44.1 88.0 3.6 1.7 78.1 27.0 84.5 24.6 20.3 18.0 33.3 0.3 174.1 7.8 79.9 67.6 10.3 46.0 9.5 0.5 14.8 1.1 33.3 32.7 30.8 0.5 1.3 7.7 8.6 45.8 7.1 38.7 42.1 7.0 2.3 2.3 7.8 177.8 0.9 0.2 58.5 1.2 26.9 0.4 18.6 4.2 36.4 18.7 43.7 104.1 19.3 176.4 16.7 22.3 123.7 0.6 49.4 9.5 43.2 2.7 52.3 0.4 0.3 2.1 78.5 0.1 46.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 137.9 134.3 119.4 187.8 134.1 136.9 154.5 131.2 126.4 123.0 144.6 114.7 11.8 0.0 0.0 82.3 0.6 1.3 2.7 56.2 5.7 62.8 17.1 11.7 0.8 4.3 22.2 5.5 18.8 31.4 0.1 0.7 1.9 80.0 0.5 12.4 7.0 11.9 15.6 0.0 22.6 13.3 28.7 7.7 9.2 27.7 0.0 57.5 11.4 0.0 3.3 254.1 29.1 2.7 20.3 0.3 1.0 1.0 1.8 0.7 0.0 7.5 3.1 188.8 0.0 12.1 3.3 63.2 1.6 3.4 0.0 9.7 0.0 0.4 4.0 165.3 6.6 4.4 15.2 1.2 4.0 5.7 0.9 27.1 0.3 19.2 2.3 7.2 TMEM144 FLJ11155 ENSG00000164124 "Transmembrane protein 144" Q7Z5S9 4 158201604-158255416 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "brain: 418.0" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 994.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.1;plasmacytoid DC: 2.2" "Group enriched" "Detected in many" 10 "dendritic cells: 2.2;monocytes: 1.4" "Cell line enhanced" "Detected in many" "BEWO: 36.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063554 Approved Mitochondria NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 28: BEWO - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA063554: AB_2685039" "unprognostic (1.26e-2)" "unprognostic (7.05e-2)" "unprognostic (2.06e-2)" "prognostic favorable (2.89e-4)" "unprognostic (2.90e-1)" "unprognostic (1.71e-5)" "unprognostic (8.27e-2)" "unprognostic (3.32e-1)" "unprognostic (2.21e-1)" "unprognostic (3.33e-2)" "prognostic unfavorable (8.48e-4)" "unprognostic (9.34e-2)" "unprognostic (1.13e-2)" "unprognostic (1.35e-1)" "unprognostic (9.26e-2)" "unprognostic (3.88e-2)" "unprognostic (4.05e-2)" 8.6 12.9 91.0 3.6 235.8 3.1 15.4 164.3 134.4 7.6 15.3 14.4 29.4 6.1 15.6 5.4 6.8 12.5 14.9 101.1 122.5 3.8 3.2 6.3 2.3 204.2 158.6 13.5 7.4 4.6 1.3 6.5 201.8 9.0 15.9 0.6 5.9 10.9 2.8 3.4 20.7 7.1 133.8 4.0 11.2 27.0 163.9 1.9 16.9 2.6 1.6 6.6 2.6 418.0 4.7 12.1 0.2 2.6 8.6 11.8 36.5 1.9 3.9 1.7 2.8 15.1 17.8 0.0 2.8 0.6 10.0 2.2 5.1 16.7 2.4 0.0 5.5 8.5 3.0 13.5 2.8 10.7 2.3 8.9 20.0 7.0 3.0 0.5 9.7 1.7 5.5 0.2 12.8 5.1 0.0 0.0 3.2 15.1 2.9 0.0 0.0 0.4 4.2 12.3 1.9 0.0 0.5 19.6 4.2 7.1 12.6 2.4 1.8 3.9 2.7 0.7 2.1 0.0 1.1 0.9 5.4 1.4 3.1 0.0 1.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.1 0.3 2.2 0.0 0.3 91.0 235.8 164.3 134.4 101.1 122.5 204.2 158.6 201.8 133.8 163.9 418.0 2.9 9.6 9.1 53.2 0.3 3.1 7.7 5.2 2.8 0.9 12.4 10.7 12.7 12.8 8.4 0.0 0.0 13.7 1.5 36.6 0.0 15.4 231.8 14.5 8.6 4.8 4.9 3.0 10.9 13.3 6.5 4.4 14.8 24.5 4.5 14.6 4.6 1.2 29.0 0.0 12.5 21.4 8.2 20.8 5.0 98.2 10.5 12.9 3.6 12.2 10.6 1.3 0.0 5.5 994.4 9.0 18.9 9.1 0.2 3.5 44.1 6.4 8.8 0.2 0.0 8.5 2.6 3.0 2.2 5.8 5.1 8.8 0.9 6.8 18.6 6.4 TMEM176A "HCA112, MS4B1" ENSG00000002933 "Transmembrane protein 176A" Q96HP8 7 150800403-150805118 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 377.7;liver: 1170.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 1043.9;Paneth cells: 779.4;Proximal enterocytes: 1294.5;Proximal tubular cells: 1103.9" "Cancer enhanced" "Detected in all" "liver cancer: 210.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 146.5;intermediate monocyte: 98.4" "Lineage enriched" "Detected in many" 5 "monocytes: 146.5" "Cell line enriched" "Detected in some" 31 "HSkMC: 730.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008770 Approved Approved Mitochondria NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA008770: AB_2256120" "unprognostic (4.70e-2)" "unprognostic (7.71e-2)" "unprognostic (5.71e-3)" "unprognostic (6.09e-2)" "unprognostic (3.96e-3)" "unprognostic (1.44e-2)" "unprognostic (2.51e-1)" "unprognostic (2.32e-1)" "unprognostic (4.19e-2)" "unprognostic (1.99e-1)" "unprognostic (1.47e-2)" "unprognostic (4.37e-2)" "unprognostic (4.79e-1)" "unprognostic (1.23e-2)" "unprognostic (1.98e-2)" "unprognostic (2.64e-1)" "unprognostic (4.91e-2)" 76.6 33.1 46.5 124.8 48.0 6.8 49.3 49.2 50.8 45.7 39.1 143.9 113.2 18.6 17.9 28.5 48.9 129.8 90.9 43.6 56.2 377.7 1170.6 58.5 85.6 64.0 56.2 104.7 29.8 3.9 11.6 66.6 58.2 26.5 151.3 20.6 24.2 15.9 6.4 20.6 203.1 50.2 61.3 51.0 48.7 6.1 49.9 15.5 21.3 17.4 66.0 98.0 54.5 63.9 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 3.5 14.2 0.2 0.6 0.0 0.3 1.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.3 0.3 730.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.6 0.9 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 23.3 0.0 0.0 2.7 0.5 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.0 146.5 12.6 0.3 98.4 0.4 2.1 0.1 0.2 30.9 0.0 0.2 0.0 1.8 0.3 46.0 2.4 0.4 53.3 46.5 48.0 49.2 50.8 43.6 56.2 64.0 56.2 58.2 61.3 49.9 63.9 15.8 0.0 5.2 3.9 9.8 7.4 0.4 0.9 5.2 56.2 40.6 63.8 24.9 118.7 10.9 200.5 4.2 0.6 2.0 348.5 152.6 64.6 0.3 4.9 14.8 20.5 74.1 6.6 0.0 27.2 0.6 185.3 17.9 2.5 29.0 29.9 23.2 1043.9 52.2 0.0 0.2 237.7 73.2 56.9 26.2 1.5 60.3 109.4 5.4 1.9 313.0 80.8 1.0 1.0 0.0 56.0 779.4 7.5 0.9 1.8 1294.5 1103.9 10.6 5.3 0.0 5.7 32.8 0.9 1.6 2.9 8.4 1.4 6.4 0.1 262.4 2.7 TMEM18 "DKFZp434C1714, lncND" ENSG00000151353 "Transmembrane protein 18" Q96B42 2 663877-677406 "Predicted membrane proteins, Transporters" Transcription DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040233 Approved Approved "Endoplasmic reticulum,Mitochondria" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "Endoplasmic reticulum" "HPA040233: AB_10794737" "unprognostic (9.01e-3)" "unprognostic (2.45e-1)" "unprognostic (7.48e-2)" "unprognostic (1.77e-3)" "unprognostic (2.68e-2)" "unprognostic (1.61e-1)" "unprognostic (1.27e-2)" "unprognostic (4.11e-2)" "prognostic unfavorable (3.21e-4)" "unprognostic (6.05e-2)" "unprognostic (1.86e-1)" "unprognostic (9.45e-2)" "unprognostic (8.20e-2)" "unprognostic (2.49e-1)" "unprognostic (3.65e-1)" "unprognostic (4.98e-3)" "unprognostic (8.08e-2)" 18.5 19.9 9.3 6.3 9.1 8.8 18.5 8.8 11.7 14.8 7.6 12.3 8.9 17.7 9.7 14.8 15.8 8.5 11.6 9.6 10.0 13.2 10.1 11.0 8.4 9.8 9.4 28.3 25.2 12.4 9.7 9.9 9.8 9.5 6.2 12.0 14.3 7.0 27.3 15.4 10.1 9.5 9.4 9.2 13.3 12.2 10.2 7.0 12.8 12.2 6.4 13.6 13.1 10.4 17.4 14.1 20.3 21.7 23.9 35.4 19.0 23.8 19.0 20.2 19.5 1.9 27.6 25.1 44.5 31.1 10.7 24.0 7.2 26.3 17.8 37.1 16.6 14.4 7.6 28.7 25.9 13.5 11.9 24.6 26.4 35.1 26.7 18.2 5.9 39.1 14.7 14.7 30.5 48.1 32.7 32.1 13.8 15.1 21.4 17.8 9.9 17.8 21.0 16.3 14.4 24.9 13.1 22.7 25.4 9.5 16.2 25.6 19.5 19.0 25.5 12.6 36.7 19.3 34.4 21.8 20.7 14.4 13.1 3.8 16.1 6.9 11.8 15.7 11.3 18.4 13.5 9.5 16.6 14.8 14.8 14.4 1.0 18.5 18.4 22.3 17.1 13.1 9.3 9.1 8.8 11.7 9.6 10.0 9.8 9.4 9.8 9.4 10.2 10.4 49.2 22.4 32.8 4.6 39.4 35.9 29.7 46.0 61.5 19.8 68.3 108.2 28.3 31.5 39.2 27.6 8.4 72.5 28.1 26.0 31.3 34.1 14.2 37.5 53.7 41.0 19.8 37.9 4.1 46.3 62.1 47.1 27.0 53.1 29.8 77.6 38.2 37.4 49.1 20.2 3.9 39.4 36.7 37.4 31.5 13.1 63.3 31.2 40.9 2.8 36.4 49.8 20.6 4.5 10.2 36.6 50.7 51.1 43.1 40.1 51.0 45.8 32.1 33.7 19.7 31.8 48.8 93.3 68.1 72.6 43.2 81.1 30.0 63.5 41.7 40.4 TMEM223 MGC3196 ENSG00000168569 "Transmembrane protein 223" A0PJW6 11 62771629-62792006 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014504 Approved Approved "Nucleoplasm,Nuclear membrane,Mitochondria" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nuclear membrane, Mitochondria" "HPA014504: AB_1853881" "unprognostic (1.35e-2)" "unprognostic (1.60e-1)" "unprognostic (1.87e-1)" "unprognostic (3.15e-2)" "unprognostic (1.00e-1)" "unprognostic (2.21e-2)" "unprognostic (3.20e-3)" "unprognostic (1.97e-1)" "unprognostic (4.35e-1)" "unprognostic (1.70e-3)" "unprognostic (1.29e-1)" "unprognostic (2.50e-1)" "unprognostic (5.20e-2)" "unprognostic (7.26e-2)" "unprognostic (1.66e-1)" "unprognostic (1.14e-3)" "unprognostic (9.75e-2)" 13.1 20.9 10.4 9.4 12.0 6.4 12.8 12.4 13.4 13.2 11.6 15.7 11.0 12.9 9.7 13.3 11.7 5.5 27.9 10.4 10.5 17.3 22.5 11.1 12.0 11.6 10.2 11.4 19.8 8.0 13.2 7.1 11.8 14.8 7.4 5.2 15.3 7.2 16.1 13.3 14.4 5.3 10.0 16.6 15.4 6.7 10.4 7.3 13.8 8.5 7.0 12.2 11.1 12.1 29.2 24.4 14.3 19.6 11.8 13.5 19.5 15.3 13.4 16.9 14.1 21.5 34.9 21.6 36.8 11.1 22.5 43.3 17.3 18.9 9.6 34.7 32.5 16.1 26.9 25.9 20.6 20.0 18.4 14.4 18.8 11.2 13.9 20.3 13.9 28.2 24.8 15.8 12.6 42.3 20.3 44.3 28.2 30.2 29.2 24.7 17.3 48.8 26.8 18.3 24.3 32.0 16.0 32.3 43.0 14.5 48.1 18.4 13.9 20.2 24.4 18.7 18.5 32.1 27.5 25.1 24.0 17.8 21.5 21.0 41.3 25.0 71.3 46.2 68.8 77.6 69.8 69.9 46.8 81.8 74.9 73.0 19.0 66.2 29.8 75.6 66.8 41.5 10.4 12.0 12.4 13.4 10.4 10.5 11.6 10.2 11.8 10.0 10.4 12.1 31.9 12.8 5.6 4.2 24.1 13.5 15.3 39.7 8.6 17.9 27.6 45.0 18.8 52.9 25.2 20.2 12.5 49.4 22.8 30.2 62.6 37.2 2.6 29.1 26.9 28.9 20.5 18.5 6.1 44.3 42.9 22.0 15.3 22.3 19.7 22.4 31.8 36.0 37.6 6.7 8.0 32.6 38.7 20.1 13.6 3.4 32.6 16.2 19.6 4.7 16.2 16.5 35.0 6.0 5.7 36.1 19.3 26.4 25.4 22.4 32.1 52.3 39.6 18.0 19.7 22.3 17.9 6.9 19.7 21.3 13.9 14.2 24.3 34.2 43.4 17.1 TMIGD1 "TMIGD, UNQ9372" ENSG00000182271 "Transmembrane and immunoglobulin domain containing 1" Q6UXZ0 17 30316333-30334059 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "intestine: 140.5" "Group enriched" "Detected in some" 28 "Distal enterocytes: 291.9;Paneth cells: 125.5;Proximal enterocytes: 476.6" "Cancer enriched" "Detected in single" 5 "colorectal cancer: 1.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA021946 Approved Mitochondria NA NA "Cluster 9: Intestine - Unknown function" "Cluster 45: Enterocytes - Digestion" Mitochondria "HPA021946: AB_1858140" "unprognostic (1.28e-1)" "unprognostic (1.30e-1)" "unprognostic (1.61e-1)" 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 80.5 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 98.5 0.0 0.0 0.0 0.0 0.0 140.5 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 291.9 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 125.5 0.0 0.0 0.0 476.6 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 7.5 0.0 TMPPE FLJ45032 ENSG00000188167 "Transmembrane protein with metallophosphoesterase domain" Q6ZT21 3 33090421-33097146 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 5.5" "Cell type enhanced" "Detected in some" "Rod photoreceptor cells: 2.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 2.4" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 6 "BEWO: 27.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027019 Approved Approved Nucleoplasm,Mitochondria Yes No "Cluster 7: Monocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Mitochondria" "HPA027019: AB_1848942" "unprognostic (1.14e-2)" "unprognostic (1.48e-1)" "unprognostic (1.00e-1)" "unprognostic (1.37e-1)" "unprognostic (5.03e-2)" "unprognostic (2.96e-2)" "unprognostic (6.34e-3)" "unprognostic (8.14e-2)" "unprognostic (1.96e-1)" "unprognostic (1.71e-1)" "unprognostic (1.25e-3)" "unprognostic (9.58e-2)" "unprognostic (1.60e-7)" "unprognostic (1.61e-1)" "unprognostic (5.40e-2)" "unprognostic (2.13e-1)" "unprognostic (4.33e-2)" 0.6 0.5 0.8 1.4 0.7 5.5 0.6 0.7 1.2 0.6 4.3 1.0 1.2 0.5 0.6 0.6 0.9 0.6 0.4 1.5 0.5 1.0 0.6 1.1 1.1 1.4 1.4 0.6 0.7 1.9 0.3 1.2 1.6 0.5 1.2 2.8 0.7 0.6 0.2 1.1 1.1 0.8 0.2 1.5 1.3 0.3 1.7 0.5 1.0 0.3 1.3 0.8 0.4 0.2 1.4 1.9 1.0 1.7 1.2 1.0 27.2 0.6 1.0 1.6 0.9 2.7 3.8 0.8 1.2 1.7 0.9 1.4 1.7 1.5 2.6 4.2 0.6 3.4 1.9 2.1 0.9 3.0 4.7 1.1 1.2 2.0 1.4 0.8 1.9 1.7 2.6 2.9 1.2 1.3 1.2 1.3 1.0 0.4 1.1 1.5 0.6 1.9 1.5 1.9 0.2 0.6 0.9 2.6 0.6 1.3 1.4 4.2 2.7 2.4 3.0 1.3 2.6 2.3 1.6 0.4 3.0 2.2 1.7 0.0 1.1 0.3 0.1 2.4 0.6 0.3 0.2 0.0 1.0 0.1 0.0 0.0 1.9 0.0 1.1 0.2 0.2 0.4 0.8 0.7 0.7 1.2 1.5 0.5 1.4 1.4 1.6 0.2 1.7 0.2 0.3 0.0 1.3 0.0 0.8 0.8 0.1 0.0 0.0 1.2 0.4 0.4 0.4 0.0 0.2 0.0 0.0 1.1 1.9 1.4 0.0 0.4 0.0 0.8 0.6 0.4 0.0 0.4 0.0 0.8 1.7 0.3 0.0 1.1 0.0 0.4 0.4 0.6 0.9 1.7 0.0 0.2 2.0 1.3 1.2 0.0 0.0 1.1 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.5 1.4 0.4 1.0 0.2 1.4 0.3 0.4 2.2 0.0 0.2 0.7 0.0 0.0 1.5 0.9 0.4 0.6 0.5 0.6 0.2 TNFRSF19 "TAJ, TAJ-alpha, TRADE, TROY" ENSG00000127863 "TNF receptor superfamily member 19" Q9NS68 13 23570370-23676104 "Plasma proteins, Predicted membrane proteins" Apoptosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 55.3;skin 1: 107.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 62.2;Microglial cells: 71.2;Respiratory ciliated cells: 62.4;Suprabasal keratinocytes: 80.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC TERT1: 46.5;BJ hTERT+: 73.2;fHDF/TERT166: 55.9;Hep G2: 83.0;SK-MEL-30: 128.4;WM-115: 76.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010135 Approved Nucleoplasm,Mitochondria No No "Cluster 35: T-regs - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 28: Keratinocytes - Keratinization" Mitochondria Nucleoplasm "HPA010135: AB_1079797" "unprognostic (5.70e-2)" "unprognostic (1.28e-1)" "unprognostic (1.17e-2)" "unprognostic (2.42e-1)" "unprognostic (2.04e-1)" "unprognostic (1.86e-3)" "unprognostic (2.01e-2)" "prognostic favorable (3.87e-4)" "unprognostic (3.74e-1)" "unprognostic (5.47e-2)" "unprognostic (4.41e-2)" "unprognostic (6.56e-2)" "prognostic favorable (9.13e-7)" "unprognostic (3.44e-2)" "unprognostic (6.05e-2)" "unprognostic (3.25e-3)" "unprognostic (5.38e-3)" 1.8 2.9 1.8 0.9 1.7 1.7 9.9 1.8 1.9 7.0 4.2 2.4 1.8 8.6 13.4 9.4 30.5 3.4 22.1 2.0 2.5 15.7 1.1 17.2 0.7 3.3 3.2 2.7 2.8 0.9 8.5 8.4 2.6 27.4 1.9 4.7 55.3 7.6 2.4 107.5 1.3 3.0 3.1 5.1 5.4 2.2 2.7 6.7 3.4 2.1 1.8 4.5 4.8 2.5 0.1 3.3 3.2 0.0 4.7 46.5 3.5 3.7 73.2 2.0 2.8 23.6 0.1 0.0 0.0 55.9 0.5 0.1 3.3 2.9 3.6 0.0 2.9 0.6 2.4 83.0 2.2 0.2 0.9 22.5 0.7 23.1 0.3 1.5 0.1 0.0 0.1 0.0 13.2 1.1 0.0 0.1 2.3 29.7 5.1 0.0 13.6 0.0 8.4 0.4 30.9 4.9 0.1 0.0 128.4 3.4 0.0 0.3 0.0 11.5 0.5 0.1 3.5 0.0 0.1 0.0 4.5 0.1 76.2 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.2 1.3 0.0 1.8 1.7 1.8 1.9 2.0 2.5 3.3 3.2 2.6 3.1 2.7 2.5 3.1 0.0 20.8 1.0 0.2 62.2 3.0 2.0 23.9 0.8 6.3 2.9 23.4 2.8 9.3 9.2 8.4 0.1 0.3 0.1 0.0 11.1 1.7 10.4 4.4 5.1 0.0 0.0 6.9 1.0 0.0 14.4 2.6 3.9 1.3 0.5 0.0 0.5 0.1 0.0 6.7 0.0 6.1 0.0 8.5 1.0 11.5 0.2 14.2 71.2 0.0 3.3 0.0 12.5 1.1 11.3 0.0 13.9 0.0 13.3 0.0 20.9 62.4 3.3 0.0 3.2 4.9 1.5 2.3 8.3 80.3 0.0 0.6 3.5 0.0 0.6 TNNC1 TNNC ENSG00000114854 "Troponin C1, slow skeletal and cardiac type" P63316 3 52451100-52454041 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Muscle protein" "Cardiomyopathy, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 36 "heart muscle: 8734.3;skeletal muscle: 21081.1;tongue: 12403.9" "Cell type enriched" "Detected in many" 10 "Cardiomyocytes: 3550.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 27.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.2" "Lineage enriched" "Detected in single" 6 "T-cells: 1.2" "Cell line enhanced" "Detected in many" "CACO-2: 68.2;CAPAN-2: 33.5;EFO-21: 65.2;HeLa: 49.1;Hep G2: 46.1;HSkMC: 67.2;U-2 OS: 97.7" "Region enriched" "Detected in all" 4 "cerebral cortex: 87.0" "Group enriched" "Detected in some" 6 "midbrain: 7.6;spinal cord: 7.1" "CAB002450, HPA044848, HPA056897" Enhanced Approved "Nucleoplasm,Actin filaments,Mitochondria" NA NA 990000 "Cluster 13: T-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 9: U-2 OS - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Actin filaments, Mitochondria" "CAB002450: AB_564152, HPA044848: AB_2679110, HPA056897: AB_2683269" "unprognostic (2.18e-2)" "unprognostic (1.70e-1)" "unprognostic (8.66e-2)" "unprognostic (3.43e-1)" "unprognostic (4.00e-2)" "unprognostic (1.88e-2)" "unprognostic (1.11e-1)" "unprognostic (1.43e-1)" "unprognostic (1.53e-1)" "unprognostic (3.92e-1)" "unprognostic (1.03e-1)" "unprognostic (1.07e-1)" "unprognostic (2.15e-2)" "unprognostic (4.95e-2)" "unprognostic (2.31e-1)" "unprognostic (4.15e-2)" "unprognostic (4.86e-1)" 8.4 10.9 0.7 0.8 0.8 0.7 19.1 2.7 1.1 7.7 7.3 4.0 1.1 2.8 41.7 387.3 2.8 3.3 8734.3 1.2 0.7 19.2 4.0 78.5 3.9 0.8 0.9 2.4 6.8 1.6 17.6 5.2 1.0 170.1 4.1 0.4 120.8 2.2 21081.1 18.9 3.3 0.8 0.8 2.8 5.7 10.6 0.8 4.3 14.4 12403.9 1.6 5.3 5.4 0.7 0.7 5.2 3.6 0.6 0.2 0.5 8.0 0.4 0.3 0.3 0.4 68.2 33.5 0.5 65.2 9.9 0.1 0.4 0.1 0.3 0.0 1.2 1.6 0.5 49.1 46.1 0.3 0.3 0.1 67.2 1.2 0.0 0.7 0.6 0.0 2.0 0.2 5.1 2.0 0.1 0.2 0.8 0.5 15.1 0.7 0.1 2.9 2.3 3.3 13.0 0.2 0.0 0.5 6.7 0.1 3.9 26.7 0.5 0.0 0.1 97.7 0.8 0.2 2.8 1.3 0.9 0.3 0.7 0.1 0.0 0.0 0.0 0.2 0.0 1.2 0.0 0.2 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.8 0.1 0.7 0.8 2.7 1.1 1.2 0.7 0.8 0.9 1.0 0.8 0.8 0.7 0.2 125.0 12.6 0.0 0.3 1.5 1.7 4.0 0.6 0.2 0.5 0.3 3550.1 5.7 7.9 3.7 2.1 59.0 0.1 1.6 27.4 11.8 0.7 66.4 6.7 39.8 330.7 0.4 0.0 13.0 5.1 52.7 0.5 98.8 0.0 0.8 0.7 0.7 4.9 0.0 0.0 1.7 2.0 0.0 1.4 5.8 22.4 2.6 5.4 0.0 0.1 1.2 0.0 0.0 0.0 6.5 0.3 177.6 0.1 0.8 0.5 1.3 2.8 0.1 0.0 241.8 36.0 2.1 1.0 0.1 0.9 31.1 2.8 1.3 2.0 6.8 TPPP "p25, p25alpha, TPPP/p25, TPPP1" ENSG00000171368 "Tubulin polymerization promoting protein" O94811 5 659862-693352 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 185.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 38.5;Excitatory neurons: 45.2;Horizontal cells: 42.1;Inhibitory neurons: 32.6;Oligodendrocytes: 104.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 7.4;AN3-CA: 5.4;SCLC-21H: 13.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036575, HPA036576" Enhanced Supported Mitochondria,Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Mitochondria, Cytosol" "HPA036575: AB_10673501, HPA036576: AB_2675200" "unprognostic (3.66e-2)" "unprognostic (3.70e-3)" "unprognostic (9.98e-3)" "unprognostic (7.82e-2)" "unprognostic (2.05e-2)" "unprognostic (3.20e-2)" "unprognostic (2.12e-1)" "unprognostic (3.80e-3)" "unprognostic (3.85e-1)" "unprognostic (1.63e-1)" "unprognostic (2.07e-3)" "unprognostic (5.48e-2)" "prognostic favorable (5.40e-6)" "unprognostic (4.03e-2)" "unprognostic (2.30e-1)" "unprognostic (2.03e-2)" "unprognostic (3.31e-2)" 3.8 6.6 100.8 0.7 136.7 0.2 2.5 55.3 120.4 1.8 0.0 12.8 5.2 3.3 0.5 11.0 10.4 1.7 9.8 112.3 69.9 4.4 2.7 10.2 0.3 110.3 102.3 1.8 6.0 2.1 19.5 2.2 107.7 2.3 1.8 6.3 5.7 3.6 10.5 8.2 9.5 3.6 47.5 2.6 4.9 2.2 124.6 0.4 6.9 5.3 1.4 6.8 2.7 185.2 0.2 7.4 0.3 5.4 0.8 0.0 1.0 0.1 0.0 0.0 0.0 0.3 0.8 0.1 0.5 0.0 1.9 2.9 2.9 0.0 0.0 1.5 2.5 0.2 3.6 0.2 0.8 0.2 0.3 0.0 0.7 0.0 0.1 0.2 0.0 0.1 0.1 2.7 0.0 0.2 0.2 0.5 0.2 0.8 0.7 0.3 0.1 1.0 0.2 1.0 13.2 1.6 0.8 0.3 3.6 0.3 0.7 0.2 0.1 0.2 2.7 0.0 0.2 1.0 0.2 0.0 0.5 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 100.8 136.7 55.3 120.4 112.3 69.9 110.3 102.3 107.7 47.5 124.6 185.2 1.6 38.5 10.0 6.8 0.7 4.1 1.4 0.6 9.6 21.3 3.1 2.4 18.4 2.8 5.3 1.8 0.0 0.0 1.1 5.7 1.9 2.4 9.1 26.6 0.9 2.0 10.2 0.0 45.2 0.7 0.3 3.3 3.1 5.8 4.5 0.1 2.2 4.3 3.3 42.1 32.6 6.5 0.0 0.0 2.2 7.2 0.3 1.2 1.8 4.7 0.1 0.9 0.0 6.6 104.7 0.7 5.2 0.4 3.3 0.8 10.3 1.1 13.5 2.4 0.0 1.5 4.2 2.2 0.8 6.7 3.1 0.0 4.8 0.1 4.8 4.1 TRABD PP2447 ENSG00000170638 "TraB domain containing" Q9H4I3 22 50185913-50199598 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000822 Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Mitochondria" "HPA000822: AB_10959384" "unprognostic (9.37e-2)" "unprognostic (1.36e-2)" "unprognostic (1.18e-1)" "prognostic favorable (1.19e-5)" "unprognostic (2.80e-1)" "unprognostic (2.79e-1)" "unprognostic (1.42e-3)" "unprognostic (6.12e-2)" "unprognostic (2.40e-1)" "unprognostic (4.68e-3)" "unprognostic (1.65e-1)" "unprognostic (3.27e-2)" "prognostic unfavorable (1.85e-4)" "unprognostic (1.08e-3)" "unprognostic (1.19e-1)" "unprognostic (2.87e-2)" "unprognostic (2.98e-3)" 19.8 20.7 7.1 27.7 6.9 60.9 18.5 10.1 10.6 23.0 5.9 24.1 18.3 16.8 3.8 40.4 18.8 11.0 21.8 7.0 6.2 26.8 40.8 26.0 32.8 8.5 6.7 18.8 72.7 7.6 21.9 8.4 6.6 29.1 6.3 3.2 29.0 9.6 29.3 23.6 30.7 5.3 6.7 36.9 27.5 20.8 7.2 16.6 24.8 5.0 15.7 22.6 27.0 6.8 62.8 40.9 14.5 24.7 7.8 9.0 35.9 21.4 14.0 17.6 14.9 26.2 29.6 38.3 20.5 10.1 13.7 38.6 18.8 38.1 3.5 27.1 87.1 22.5 71.2 46.0 30.5 45.4 42.7 14.6 22.9 12.9 17.7 10.3 17.9 37.3 27.8 61.7 7.6 70.5 32.5 51.2 21.3 21.3 38.0 87.6 19.7 83.0 13.4 61.5 16.8 28.0 18.4 66.2 31.3 6.1 28.0 47.0 19.4 14.6 36.2 19.2 24.4 73.9 14.1 46.7 18.0 31.5 23.5 16.9 30.5 51.4 21.2 26.5 20.3 13.6 19.1 19.5 32.5 6.7 12.6 15.3 40.6 32.1 16.7 68.7 29.5 22.4 7.1 6.9 10.1 10.6 7.0 6.2 8.5 6.7 6.6 6.7 7.2 6.8 22.2 9.6 19.3 12.1 80.3 42.1 57.4 48.9 33.6 32.6 38.8 30.1 12.0 17.2 31.8 33.1 18.8 25.5 151.7 66.2 27.4 52.3 20.7 17.1 25.1 27.2 18.0 17.4 11.6 62.9 54.5 27.2 77.5 32.4 27.3 31.6 12.8 24.0 46.4 43.7 12.9 55.3 46.8 46.9 59.4 8.8 32.3 69.6 42.7 9.4 111.4 22.5 117.4 14.1 15.3 80.6 67.7 32.4 133.1 125.9 55.0 28.9 19.7 32.8 19.7 20.5 23.7 49.9 31.5 34.3 45.6 30.6 84.3 31.2 71.0 92.5 TRIAP1 "HSPC132, MDM35, P53CSV, WF-1" ENSG00000170855 "TP53 regulated inhibitor of apoptosis 1" O43715 12 120443964-120446384 "Predicted intracellular proteins, Transporters" "Apoptosis, Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 128.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053640 Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Mitochondria" "HPA053640: AB_2682213" "unprognostic (8.74e-3)" "unprognostic (9.44e-2)" "unprognostic (5.24e-2)" "unprognostic (4.06e-2)" "unprognostic (3.07e-1)" "unprognostic (1.40e-1)" "unprognostic (1.19e-2)" "unprognostic (3.31e-2)" "prognostic unfavorable (2.22e-4)" "unprognostic (9.87e-3)" "unprognostic (4.39e-2)" "unprognostic (9.93e-2)" "prognostic unfavorable (8.77e-4)" "unprognostic (8.81e-2)" "unprognostic (2.00e-1)" "unprognostic (6.44e-2)" "unprognostic (4.97e-2)" 21.8 24.6 16.6 18.9 16.8 32.9 28.4 17.1 23.0 16.6 18.0 24.6 19.2 14.1 20.8 22.9 17.2 15.4 19.4 16.8 17.5 21.1 66.4 16.8 24.8 16.9 16.7 12.1 52.5 14.7 12.3 29.1 17.1 20.1 30.5 8.8 25.3 15.3 60.4 27.0 18.5 20.9 17.2 16.3 19.6 13.2 16.9 25.7 15.7 39.1 27.5 24.1 15.6 18.2 56.2 75.1 67.4 46.3 57.5 88.1 161.0 71.8 51.2 62.5 51.6 63.2 30.4 110.0 59.6 59.2 25.0 37.4 79.3 118.6 65.8 49.1 88.5 66.9 48.7 167.9 85.4 113.6 49.6 91.6 146.7 61.4 87.0 62.3 131.1 59.8 109.3 27.7 92.1 70.3 86.0 152.7 96.5 67.9 60.4 70.4 63.5 114.4 81.1 62.0 66.3 43.2 82.7 28.1 64.6 105.7 93.9 65.6 74.8 40.0 60.7 40.7 44.1 70.6 120.6 118.5 61.5 86.9 71.2 26.7 47.1 18.2 41.0 52.7 48.8 35.1 39.2 39.0 59.1 31.8 48.3 43.1 4.0 49.6 36.5 53.1 37.3 45.0 16.6 16.8 17.1 23.0 16.8 17.5 16.9 16.7 17.1 17.2 16.9 18.2 25.8 3.2 15.2 3.6 30.5 51.2 28.5 108.2 44.3 10.6 35.9 44.1 12.1 45.8 36.0 7.3 6.2 128.5 29.4 16.9 66.5 48.4 8.3 22.4 27.7 34.3 22.1 23.7 3.9 50.4 91.2 23.1 15.3 16.4 17.2 34.9 24.3 63.3 52.0 3.3 2.9 22.6 40.7 23.3 27.6 5.7 16.4 19.1 39.2 1.0 48.0 15.4 44.3 3.0 4.7 43.2 20.7 18.4 19.8 37.7 30.1 49.4 25.4 9.5 19.7 18.9 27.3 34.5 31.4 45.6 71.3 75.4 28.3 47.0 39.5 28.9 TRIM3 "BERP, HAC1, RNF22, RNF97" ENSG00000110171 "Tripartite motif containing 3" O75382 11 6448613-6474459 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 28.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SK-BR-3: 54.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043396, HPA048233" Enhanced Approved Mitochondria NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 45: Enterocytes - Digestion" Mitochondria "HPA043396: AB_2678460, HPA048233: AB_2680321" "unprognostic (1.24e-1)" "unprognostic (1.98e-1)" "unprognostic (2.31e-1)" "prognostic favorable (2.20e-4)" "unprognostic (4.01e-2)" "unprognostic (3.88e-2)" "unprognostic (1.61e-3)" "unprognostic (2.84e-1)" "unprognostic (2.24e-1)" "unprognostic (3.91e-1)" "prognostic favorable (5.49e-5)" "unprognostic (2.01e-1)" "prognostic unfavorable (1.07e-5)" "unprognostic (2.51e-1)" "unprognostic (1.66e-1)" "unprognostic (1.54e-1)" "unprognostic (1.93e-1)" 9.5 4.6 6.4 4.6 6.2 1.3 10.3 11.6 7.5 11.2 0.0 13.0 17.8 13.5 1.8 4.8 10.1 4.1 8.0 5.8 3.4 6.3 6.3 9.7 2.4 8.5 3.1 8.7 6.4 2.7 5.9 3.9 9.4 9.5 4.8 4.8 9.0 5.4 11.5 8.4 15.7 5.6 2.2 5.7 10.1 3.8 5.9 1.5 6.8 4.8 1.6 11.2 9.3 6.1 7.2 12.4 4.9 8.3 8.1 7.8 6.7 10.3 6.1 7.8 8.6 7.6 5.0 3.9 3.6 7.9 9.1 5.0 5.1 7.7 3.0 4.8 7.6 1.2 13.5 5.3 5.2 0.4 4.1 6.7 3.7 6.1 3.2 3.3 8.0 2.9 1.7 4.7 7.8 15.2 0.3 1.0 3.5 15.2 10.7 2.4 4.2 4.9 1.9 3.8 5.1 7.8 5.7 54.9 6.6 2.5 20.8 1.3 13.4 20.3 9.5 15.0 6.9 5.5 3.6 0.8 11.0 1.7 7.6 0.0 1.0 0.6 0.5 1.0 0.4 0.1 0.4 0.4 1.2 0.1 0.1 0.6 0.0 0.6 0.2 0.2 0.5 0.5 6.4 6.2 11.6 7.5 5.8 3.4 8.5 3.1 9.4 2.2 5.9 6.1 8.5 6.4 0.0 9.8 2.4 4.8 2.8 2.8 3.4 8.8 8.5 6.0 2.2 2.8 2.7 0.0 10.4 1.8 3.5 16.0 0.0 3.1 3.9 2.8 4.4 6.5 4.8 0.4 13.2 3.5 2.2 6.9 5.6 7.3 1.3 3.6 4.6 2.5 4.7 8.4 12.2 11.4 4.1 0.8 6.5 5.6 5.9 3.5 7.2 11.2 3.4 2.2 3.1 5.0 10.2 3.1 5.4 5.3 2.5 3.2 28.7 3.1 8.4 9.6 13.1 5.0 11.3 3.1 6.0 3.7 5.4 0.8 3.4 3.3 6.6 2.3 TRMT12 "FLJ20772, Trm12, TYW2" ENSG00000183665 "TRNA methyltransferase 12 homolog" Q53H54 8 124450820-124462150 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "tRNA processing" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 73.1" "Low region specificity" "Detected in all" HPA023939 Approved Approved Nucleoplasm,Mitochondria No No "Cluster 22: NK-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm Mitochondria "HPA023939: AB_1848793" "unprognostic (2.54e-2)" "unprognostic (2.20e-1)" "unprognostic (7.81e-2)" "unprognostic (1.02e-2)" "unprognostic (8.75e-2)" "prognostic unfavorable (2.99e-5)" "prognostic unfavorable (5.10e-4)" "unprognostic (6.89e-2)" "unprognostic (1.99e-1)" "unprognostic (1.28e-1)" "unprognostic (1.51e-1)" "unprognostic (6.56e-2)" "unprognostic (4.72e-3)" "unprognostic (3.39e-2)" "unprognostic (2.40e-1)" "prognostic unfavorable (9.25e-4)" "unprognostic (1.04e-2)" 6.0 5.8 5.0 5.4 5.1 3.1 8.7 4.3 6.7 6.5 5.5 5.7 4.6 6.5 6.1 5.6 7.6 4.4 5.9 6.5 4.8 7.6 6.0 5.9 6.5 3.6 3.9 5.0 5.1 8.6 4.7 5.4 4.1 6.9 6.5 8.1 7.7 6.1 9.7 5.3 5.0 8.2 3.4 5.5 5.7 6.4 5.5 8.3 8.8 10.0 6.7 6.7 4.3 4.9 14.8 12.6 10.3 8.1 19.0 9.7 2.5 9.1 10.6 13.1 11.2 7.7 10.0 14.9 12.3 9.4 8.5 10.1 14.7 14.9 15.4 14.8 11.2 14.4 12.8 2.6 14.8 0.0 11.2 12.1 19.6 12.9 16.2 3.8 11.1 15.4 20.4 10.1 8.2 73.1 17.2 6.1 0.0 33.9 11.5 5.4 6.9 9.9 12.1 15.7 17.3 13.8 13.4 49.5 19.5 8.7 14.1 6.1 8.9 9.1 23.8 6.8 10.4 10.4 15.6 5.8 8.2 5.0 7.5 0.4 3.5 3.8 2.3 2.9 3.0 2.1 3.2 2.5 2.8 2.8 3.9 3.9 1.3 3.1 3.3 0.8 2.1 2.4 5.0 5.1 4.3 6.7 6.5 4.8 3.6 3.9 4.1 3.4 5.5 4.9 4.9 9.6 7.5 2.0 11.2 5.2 6.1 3.5 7.4 5.6 5.5 4.7 3.9 7.2 2.2 3.7 16.7 7.3 8.4 4.2 5.9 5.6 18.6 6.3 4.9 5.7 3.0 1.7 1.5 6.2 5.4 4.5 6.6 3.6 9.5 7.7 4.2 5.4 5.1 8.4 1.8 4.4 4.1 4.1 2.5 21.0 4.1 5.2 5.4 1.0 8.1 4.0 9.2 1.0 1.2 4.3 3.9 6.0 8.4 4.8 3.9 8.2 7.6 8.2 0.0 8.2 6.5 14.2 5.8 4.7 4.3 4.9 6.3 7.9 4.9 4.6 TRMT61A "C14orf172, FLJ40452, GCD14, Gcd14p, hTRM61" ENSG00000166166 "TRNA methyltransferase 61A" Q96FX7 14 103529196-103537073 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 62.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 10.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024269 Approved Mitochondria NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 43: Cardiomyocytes - Nuclear processes" Mitochondria "HPA024269: " "unprognostic (5.12e-2)" "unprognostic (2.73e-2)" "unprognostic (1.36e-1)" "unprognostic (5.59e-3)" "unprognostic (1.49e-1)" "unprognostic (3.70e-2)" "prognostic unfavorable (1.60e-4)" "unprognostic (1.94e-1)" "unprognostic (3.29e-1)" "unprognostic (2.20e-1)" "unprognostic (3.70e-2)" "unprognostic (9.86e-3)" "unprognostic (2.88e-3)" "unprognostic (4.16e-1)" "unprognostic (2.79e-1)" "unprognostic (1.42e-1)" "unprognostic (1.28e-1)" 10.5 10.0 11.2 4.5 13.6 4.5 9.6 11.2 14.4 15.2 8.1 24.3 4.4 18.7 2.3 9.7 18.9 2.4 7.5 10.9 10.0 13.9 11.6 8.1 3.7 11.9 11.6 10.8 11.0 3.0 7.5 2.7 11.0 17.1 1.7 1.5 7.4 7.0 9.9 10.8 9.6 4.3 10.7 7.6 12.4 8.3 11.7 2.3 15.3 2.6 1.8 21.3 11.2 12.8 10.0 24.4 3.7 7.6 3.8 3.9 15.1 10.8 4.8 13.3 7.2 33.4 16.8 16.1 13.3 5.7 7.8 25.2 8.0 8.3 3.7 11.0 15.0 12.3 9.6 18.0 6.7 15.9 9.2 4.4 10.4 11.6 4.7 3.1 2.3 11.4 18.5 7.6 4.5 28.9 19.6 12.2 12.9 20.7 48.8 24.0 11.6 13.9 5.4 14.5 19.4 12.2 12.4 11.5 14.7 1.4 21.5 9.3 4.6 12.0 12.8 31.9 22.4 10.2 7.0 20.2 12.8 12.7 23.3 0.0 2.1 0.3 2.6 5.4 1.9 2.5 2.1 2.8 3.3 2.6 2.3 2.3 0.0 2.7 10.8 2.2 1.6 2.2 11.2 13.6 11.2 14.4 10.9 10.0 11.9 11.6 11.0 10.7 11.7 12.8 9.8 0.0 6.0 4.9 11.0 26.1 19.9 7.7 6.8 13.7 11.5 13.5 62.7 7.2 4.7 7.3 4.2 13.0 7.2 19.2 17.6 19.4 4.0 6.0 15.7 10.6 10.7 2.5 4.1 12.2 15.5 13.6 8.2 7.2 2.5 12.6 3.9 9.9 12.3 30.3 3.2 10.4 4.1 7.8 7.8 18.9 11.1 6.6 10.6 2.8 12.8 9.4 4.1 0.5 4.8 19.7 9.3 18.4 6.3 22.8 6.3 15.7 5.0 11.2 0.0 12.5 15.4 6.9 12.5 8.5 30.0 12.0 7.0 10.7 19.4 13.6 TRPT1 MGC11134 ENSG00000149743 "TRNA phosphotransferase 1" Q86TN4 11 64223799-64226254 "Enzymes, Predicted intracellular proteins" "tRNA processing" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 173.8" "Cell type enhanced" "Detected in many" "Early spermatids: 147.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038705, HPA038706" Uncertain Approved Mitochondria NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 27: Mucus-secreting cells - Mucin production" Mitochondria "HPA038705: AB_2676161, HPA038706: AB_10671863" "unprognostic (2.50e-2)" "unprognostic (1.72e-1)" "unprognostic (1.33e-1)" "unprognostic (3.59e-2)" "unprognostic (7.20e-2)" "unprognostic (1.53e-1)" "unprognostic (5.84e-2)" "unprognostic (8.56e-2)" "unprognostic (1.18e-1)" "unprognostic (3.26e-3)" "unprognostic (1.12e-1)" "unprognostic (7.71e-2)" "unprognostic (7.38e-2)" "unprognostic (2.49e-1)" "unprognostic (3.28e-1)" "unprognostic (1.99e-1)" "unprognostic (4.58e-3)" 27.6 38.8 33.1 14.1 34.9 8.4 27.5 36.3 36.2 26.3 33.8 35.2 22.2 23.1 21.4 35.2 26.3 15.4 88.3 31.7 34.6 52.0 46.5 20.3 16.3 35.0 34.0 26.0 51.3 19.2 35.2 10.9 33.7 36.0 18.4 12.7 38.9 28.4 173.8 27.4 30.3 12.0 34.1 30.8 41.9 51.1 36.7 21.1 33.5 116.1 17.6 30.0 25.8 34.3 25.1 24.5 26.5 43.0 32.0 23.5 32.2 16.4 31.6 28.7 24.0 16.1 37.1 24.7 63.6 27.4 22.2 34.1 11.8 35.7 10.1 23.8 14.2 12.7 23.8 28.0 46.4 16.2 21.4 17.7 20.7 31.6 28.1 52.7 20.4 49.0 22.3 27.1 24.2 59.4 30.3 33.7 16.8 33.3 26.1 39.3 19.5 71.4 74.4 29.1 23.0 33.4 13.2 32.1 47.5 18.0 37.1 25.8 23.9 19.4 14.9 37.9 16.4 53.0 14.3 16.3 46.7 8.3 32.1 11.0 16.9 28.5 18.8 31.2 15.0 38.0 18.5 19.9 24.4 39.9 20.1 23.3 15.8 26.1 27.4 59.0 25.2 12.0 33.1 34.9 36.3 36.2 31.7 34.6 35.0 34.0 33.7 34.1 36.7 34.3 17.1 9.6 23.1 9.8 31.4 13.3 18.7 32.7 28.5 8.9 40.4 45.3 42.5 32.9 25.5 27.6 0.0 44.4 17.0 66.3 95.9 41.4 147.5 41.3 20.1 17.5 26.9 14.9 2.8 58.4 46.7 19.8 41.8 27.5 24.6 10.0 21.0 30.0 25.5 10.1 4.9 111.3 30.5 18.9 12.8 82.1 19.9 15.0 37.4 2.8 27.2 32.1 15.5 7.5 6.8 46.6 60.5 17.0 47.1 24.0 92.0 82.9 48.2 11.6 6.6 22.4 29.3 59.6 13.4 42.8 18.5 36.0 21.8 20.2 40.3 22.6 TTC27 FLJ20272 ENSG00000018699 "Tetratricopeptide repeat domain 27" Q6P3X3 2 32628032-32821051 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 66.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031246 Approved Approved Nucleoli,Mitochondria No No "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria Nucleoli "HPA031246: AB_10603139" "unprognostic (3.10e-2)" "unprognostic (8.84e-2)" "unprognostic (3.21e-3)" "unprognostic (6.28e-3)" "unprognostic (8.90e-2)" "unprognostic (2.33e-1)" "prognostic unfavorable (1.42e-5)" "unprognostic (7.68e-2)" "unprognostic (2.30e-1)" "unprognostic (2.13e-1)" "unprognostic (2.07e-3)" "unprognostic (1.58e-1)" "prognostic unfavorable (7.32e-4)" "unprognostic (1.37e-1)" "unprognostic (2.96e-1)" "unprognostic (2.26e-1)" "unprognostic (2.15e-1)" 7.9 8.2 3.4 8.1 4.4 7.5 12.2 3.9 4.1 7.7 3.6 7.3 5.7 9.1 8.9 9.2 9.6 5.4 8.6 3.2 6.2 7.3 7.9 6.3 9.4 3.8 3.3 11.7 8.3 10.8 4.4 8.3 4.1 6.9 8.6 5.2 8.9 5.6 9.9 8.4 5.9 9.3 3.4 8.6 6.7 12.5 4.6 7.5 9.9 8.4 11.3 9.5 7.1 8.2 43.0 20.6 13.9 10.5 11.5 23.1 6.7 17.5 14.2 26.3 22.9 31.6 25.3 37.3 15.2 26.3 27.3 21.2 22.4 27.4 38.1 17.9 27.4 42.0 10.3 43.7 21.9 40.7 21.3 15.3 24.5 32.0 34.5 12.9 24.4 9.2 59.5 10.7 23.6 17.0 32.4 14.0 25.3 18.9 21.3 21.2 29.9 32.1 20.2 24.8 11.4 16.6 14.3 13.1 16.7 16.1 16.2 9.6 20.6 16.4 18.2 19.8 30.3 15.0 4.1 41.8 17.8 31.2 17.9 0.0 4.7 0.0 9.1 10.0 10.1 9.9 10.1 9.1 10.5 9.7 12.6 9.8 0.2 9.3 7.1 4.9 9.6 5.9 3.4 4.4 3.9 4.1 3.2 6.2 3.8 3.3 4.1 3.4 4.6 8.2 6.8 9.6 10.4 19.9 10.1 5.6 9.2 7.2 8.0 5.1 6.3 4.3 8.2 4.3 8.8 0.0 4.2 13.4 4.8 2.2 7.9 10.1 18.2 5.6 6.7 8.0 7.3 6.3 27.6 9.5 12.7 8.8 7.7 5.2 12.0 12.0 3.9 4.9 7.6 3.3 33.7 4.5 2.0 8.1 4.6 2.7 8.4 4.0 5.4 27.2 6.5 5.5 1.0 32.2 66.7 5.1 4.7 7.2 6.5 7.0 2.2 4.8 12.4 6.0 6.6 9.7 6.4 28.3 11.3 7.4 5.7 6.4 8.2 9.9 7.9 6.8 TTC32 ENSG00000183891 "Tetratricopeptide repeat domain 32" Q5I0X7 2 19896631-19901983 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 113.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036024 Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Mitochondria Nucleoplasm "HPA036024: AB_10673493" "unprognostic (2.77e-3)" "unprognostic (5.44e-2)" "unprognostic (8.85e-2)" "unprognostic (8.80e-3)" "unprognostic (1.08e-1)" "unprognostic (2.62e-1)" "unprognostic (5.25e-2)" "prognostic favorable (9.44e-4)" "unprognostic (4.46e-2)" "unprognostic (1.48e-2)" "unprognostic (4.92e-3)" "unprognostic (6.22e-2)" "prognostic unfavorable (5.45e-6)" "unprognostic (1.21e-1)" "unprognostic (1.40e-1)" "unprognostic (1.72e-2)" "unprognostic (2.27e-2)" 11.8 8.8 8.7 12.3 10.5 34.7 16.6 13.6 17.2 12.3 8.6 11.7 12.2 13.9 26.0 7.4 11.9 6.7 7.1 8.8 9.1 11.4 12.3 10.0 15.5 10.6 10.0 16.5 8.6 8.2 11.3 8.5 11.3 16.0 10.2 33.0 11.1 9.3 22.5 13.8 13.1 8.0 9.5 15.6 11.4 12.5 9.7 19.7 12.4 7.7 10.1 11.3 11.2 14.2 22.5 14.4 12.8 9.6 5.6 12.3 2.7 4.8 8.0 7.7 5.0 7.3 25.6 14.5 2.7 5.1 9.6 14.6 5.6 15.4 4.9 21.3 23.3 14.8 20.4 12.8 12.1 14.2 25.5 11.7 9.6 8.6 20.4 6.5 7.5 23.3 27.1 28.5 6.4 6.8 10.7 21.7 9.6 8.4 24.1 12.6 8.5 24.1 21.6 8.6 20.6 19.1 16.1 8.5 18.2 14.1 11.9 5.5 5.6 11.6 12.4 11.5 6.6 29.8 27.3 24.0 17.9 13.9 6.7 9.2 7.6 23.1 7.3 5.7 8.7 12.2 11.6 7.8 7.2 11.9 15.8 12.2 28.0 6.7 6.9 5.0 15.6 4.9 8.7 10.5 13.6 17.2 8.8 9.1 10.6 10.0 11.3 9.5 9.7 14.2 23.2 9.6 14.4 8.5 24.7 18.9 33.4 36.0 34.7 66.9 27.4 39.0 15.8 15.7 26.4 12.9 14.6 14.6 13.7 10.0 45.0 12.2 27.2 25.8 6.1 16.2 28.3 34.0 7.1 24.8 8.7 19.6 14.8 13.2 8.8 7.2 7.5 24.1 9.1 42.1 8.6 19.9 32.6 8.8 8.9 7.2 19.9 17.4 7.2 5.6 14.6 67.8 11.3 9.5 22.0 14.6 12.9 9.8 12.3 15.8 13.7 28.5 48.7 39.2 13.1 21.1 21.3 113.2 38.7 22.4 26.1 9.6 21.6 9.0 11.7 26.7 TTC9B FLJ30373 ENSG00000174521 "Tetratricopeptide repeat domain 9B" Q8N6N2 19 40216058-40218399 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 41 "brain: 110.8;choroid plexus: 32.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 39.1;Excitatory neurons: 39.3;Horizontal cells: 18.5;Inhibitory neurons: 19.7;Oligodendrocyte precursor cells: 27.2" "Cancer enriched" "Detected in single" 15 "glioma: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 19 "SCLC-21H: 26.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042496 Approved Approved Nucleoplasm,Vesicles,Mitochondria "Secreted in brain" NA NA "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Mitochondria" Vesicles "HPA042496: AB_10795506" "unprognostic (2.31e-1)" "unprognostic (1.39e-4)" "unprognostic (5.09e-2)" "unprognostic (5.24e-2)" "unprognostic (8.47e-2)" "unprognostic (1.05e-1)" "unprognostic (1.49e-1)" "unprognostic (2.10e-1)" "unprognostic (7.95e-2)" "unprognostic (2.78e-1)" "unprognostic (1.54e-2)" "unprognostic (3.69e-1)" "unprognostic (8.75e-6)" "unprognostic (1.39e-1)" "unprognostic (8.23e-2)" "unprognostic (1.95e-1)" "unprognostic (5.24e-2)" 0.0 0.6 73.9 0.3 74.7 0.0 0.0 49.7 110.8 0.0 32.9 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 84.2 60.6 0.2 0.0 0.0 0.0 45.1 46.3 0.0 0.0 0.0 0.9 0.0 46.4 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.5 0.1 43.0 0.0 0.2 0.3 60.4 0.0 0.0 0.0 0.0 0.0 0.1 69.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 26.8 1.4 0.1 0.0 1.0 0.0 0.1 0.0 0.0 0.3 0.4 0.1 0.0 0.3 0.3 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 73.9 74.7 49.7 110.8 84.2 60.6 45.1 46.3 46.4 43.0 60.4 69.0 0.0 0.0 0.0 2.9 0.0 0.0 0.1 0.1 0.0 39.1 0.2 0.0 2.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 1.8 0.2 0.2 1.8 0.0 39.3 0.5 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.1 18.5 19.7 0.1 0.0 0.0 0.0 1.0 0.3 0.0 0.0 4.7 0.0 1.7 0.0 27.2 5.0 0.1 1.2 0.7 0.0 0.1 0.0 0.0 1.2 8.4 0.0 0.0 0.1 7.0 8.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 TTLL1 C22orf7 ENSG00000100271 "Tubulin tyrosine ligase like 1" O95922 22 43039516-43089419 "Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 39.9;Spermatogonia: 32.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048392 Approved Approved Nucleoli,Mitochondria No No "Cluster 16: MAIT-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoli Mitochondria "HPA048392: AB_2680384" "unprognostic (1.02e-1)" "unprognostic (4.06e-3)" "unprognostic (1.51e-1)" "prognostic favorable (1.85e-4)" "unprognostic (6.18e-3)" "unprognostic (4.27e-3)" "prognostic unfavorable (2.34e-5)" "unprognostic (8.22e-2)" "unprognostic (2.16e-2)" "unprognostic (3.29e-1)" "unprognostic (4.47e-3)" "unprognostic (1.82e-1)" "prognostic favorable (1.68e-4)" "unprognostic (1.24e-1)" "unprognostic (1.64e-1)" "unprognostic (2.03e-1)" "unprognostic (3.38e-2)" 4.0 7.2 9.9 2.7 10.0 2.2 4.6 10.0 12.1 4.9 6.9 5.2 1.8 5.8 8.1 3.8 9.8 3.9 8.5 11.0 10.1 5.3 1.7 3.8 3.8 7.6 8.3 5.4 3.6 5.9 9.7 2.7 8.3 4.9 3.1 11.3 4.7 3.8 3.4 4.8 3.1 4.0 7.8 3.2 4.0 13.5 10.7 5.6 7.0 3.7 3.4 4.6 4.8 8.8 0.9 0.8 17.5 12.3 18.8 17.1 0.5 5.8 6.5 3.3 5.6 0.0 2.6 1.0 3.5 10.6 1.8 0.6 1.5 1.5 3.4 1.4 2.7 1.7 0.6 1.6 13.3 4.5 2.2 13.5 21.8 2.0 5.4 14.3 10.7 14.2 0.5 10.8 12.3 5.5 4.3 7.4 2.2 4.6 1.2 9.3 9.2 0.2 6.1 1.5 4.0 8.2 4.6 2.4 16.0 9.1 6.3 7.4 10.1 3.4 2.3 7.7 0.8 3.6 0.7 0.5 9.1 8.2 6.2 4.7 5.5 6.7 10.6 5.9 11.2 2.7 9.8 12.3 9.8 4.5 8.4 10.5 1.2 10.5 4.8 6.5 6.4 5.7 9.9 10.0 10.0 12.1 11.0 10.1 7.6 8.3 8.3 7.8 10.7 8.8 3.8 0.0 2.7 3.9 1.5 2.3 2.4 5.9 2.8 5.1 6.2 7.2 5.0 1.5 5.6 1.8 6.2 2.7 3.4 1.1 15.6 7.3 39.9 12.8 6.6 4.1 0.0 2.1 8.8 4.9 1.3 5.9 3.6 4.1 1.3 9.2 5.7 0.3 4.9 5.0 9.0 3.0 16.2 4.0 2.2 18.2 4.1 2.4 8.8 3.7 4.4 6.4 7.2 4.0 3.8 4.5 6.6 6.0 0.5 2.4 0.6 7.2 20.0 11.5 6.6 5.6 3.7 10.7 32.6 4.8 2.7 0.7 5.9 5.5 1.8 2.2 TTLL4 KIAA0173 ENSG00000135912 "Tubulin tyrosine ligase like 4" Q14679 2 218710835-218755416 "Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 39.4;Muller glia cells: 72.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027091, HPA050252" Approved Approved Mitochondria NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 39: CACO-2 - Unknown function" "Cluster 5: Muller glia cells - Visual perception" Mitochondria "HPA027091: AB_10601828, HPA050252: AB_2681064" "unprognostic (1.76e-1)" "unprognostic (1.91e-1)" "unprognostic (4.64e-1)" "unprognostic (1.49e-2)" "unprognostic (2.09e-1)" "unprognostic (1.66e-2)" "prognostic unfavorable (2.95e-5)" "unprognostic (3.83e-3)" "unprognostic (2.96e-2)" "unprognostic (1.21e-1)" "unprognostic (7.52e-2)" "unprognostic (2.42e-2)" "prognostic unfavorable (6.63e-12)" "unprognostic (9.84e-2)" "unprognostic (1.09e-1)" "unprognostic (1.85e-1)" "unprognostic (5.29e-3)" 3.9 7.2 7.1 8.4 9.9 5.8 6.4 7.5 9.6 5.4 20.1 5.5 5.6 4.7 3.5 6.9 7.3 4.2 4.6 7.2 8.4 4.4 5.9 6.9 6.2 9.7 11.2 4.5 7.1 5.2 6.7 8.0 10.1 6.6 6.4 15.2 6.8 3.7 5.6 8.6 5.8 5.2 7.2 5.7 8.9 25.5 9.6 5.7 3.9 2.9 8.9 5.2 6.3 10.6 18.4 12.3 32.3 16.4 8.1 6.3 43.5 12.2 9.8 19.8 16.8 52.6 21.4 14.4 10.1 9.5 18.9 19.0 34.3 16.9 23.0 16.3 27.3 18.5 19.0 50.2 11.5 23.6 13.1 10.4 10.1 17.7 19.9 8.5 19.0 16.0 53.8 22.2 11.0 10.7 13.1 15.3 36.4 13.5 8.1 29.4 14.6 18.9 19.7 14.5 12.9 12.7 9.3 13.7 23.9 48.9 11.1 12.0 7.6 17.6 17.9 11.3 11.7 11.2 10.1 32.4 9.2 14.5 23.4 0.1 12.6 0.8 3.1 6.0 2.9 3.9 2.3 2.3 7.3 3.5 1.5 1.4 14.5 2.1 8.8 4.3 1.3 5.1 7.1 9.9 7.5 9.6 7.2 8.4 9.7 11.2 10.1 7.2 9.6 10.6 1.6 3.2 5.8 28.4 3.1 4.6 12.3 3.2 4.6 6.6 4.5 5.1 3.5 5.7 4.2 7.3 27.1 6.8 3.0 2.4 0.0 6.0 39.4 7.8 3.1 3.7 5.4 6.5 3.9 3.9 8.0 4.8 10.2 5.3 1.3 4.2 1.8 2.6 7.8 3.3 4.8 4.7 4.1 5.5 2.9 16.1 3.1 9.4 3.6 15.9 10.4 72.7 5.2 11.1 20.8 5.8 2.5 1.5 2.8 15.2 2.9 1.8 7.5 12.7 0.0 3.3 3.1 18.3 12.7 4.2 4.1 5.7 2.5 2.1 5.1 11.4 TXNDC16 KIAA1344 ENSG00000087301 "Thioredoxin domain containing 16" Q9P2K2 14 52430596-52552522 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 26.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 69.8;Glandular and luminal cells: 124.9;Inhibitory neurons: 88.8" "Cancer enhanced" "Detected in all" "prostate cancer: 18.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002543 Approved Approved Mitochondria "Secreted to blood" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 44: Endometrium - Transcription" Mitochondria "HPA002543: AB_1079199" "unprognostic (1.37e-1)" "unprognostic (7.79e-3)" "unprognostic (5.95e-3)" "unprognostic (2.36e-1)" "unprognostic (5.95e-3)" "unprognostic (9.73e-2)" "unprognostic (2.50e-1)" "unprognostic (1.43e-2)" "unprognostic (7.01e-2)" "unprognostic (1.49e-1)" "unprognostic (2.07e-2)" "unprognostic (1.21e-1)" "prognostic favorable (6.79e-4)" "unprognostic (1.39e-1)" "unprognostic (1.56e-1)" "unprognostic (3.55e-3)" "unprognostic (2.04e-1)" 6.2 4.0 4.6 3.5 4.6 5.1 6.9 10.1 6.0 9.3 0.6 5.8 4.1 6.9 14.6 3.7 4.1 5.2 3.7 4.9 4.3 5.0 7.4 4.4 4.5 3.9 4.0 10.3 6.4 7.0 3.8 5.8 4.3 26.7 5.9 9.1 4.0 13.0 2.0 4.6 4.8 4.3 4.0 10.2 6.3 7.1 4.1 5.9 4.0 4.0 3.9 3.4 3.8 6.7 8.3 0.8 8.9 5.0 6.5 4.7 7.0 2.7 3.6 4.5 8.7 3.0 6.6 13.5 8.9 2.2 2.8 7.7 10.3 3.7 6.9 5.7 13.5 6.2 6.2 2.8 4.7 7.4 2.9 8.8 3.4 5.8 4.2 4.0 5.1 5.8 8.0 20.4 3.9 4.0 9.3 5.1 9.9 5.5 4.9 18.4 16.9 12.4 5.7 8.4 29.0 10.0 13.2 13.5 3.9 7.5 8.6 5.4 2.7 6.0 3.0 6.9 4.6 5.6 8.0 13.5 1.7 7.7 3.5 1.3 3.0 1.2 1.3 2.4 1.3 0.5 1.3 0.9 2.6 0.3 0.6 0.6 1.7 0.6 2.9 1.0 2.4 1.0 4.6 4.6 10.1 6.0 4.9 4.3 3.9 4.0 4.3 4.0 4.1 6.7 9.1 9.6 6.4 23.2 6.1 6.6 6.0 2.5 9.6 42.3 26.6 19.0 10.1 8.6 5.0 7.3 8.4 2.3 15.1 8.8 1.9 5.2 4.0 69.8 9.6 7.4 18.5 21.8 61.0 3.9 1.6 7.2 13.3 124.9 2.5 13.9 15.4 14.1 3.3 10.1 88.8 17.9 0.0 18.8 8.6 4.2 27.7 13.0 1.8 24.4 5.9 7.3 7.2 45.8 51.5 1.3 8.5 52.3 11.3 19.0 5.9 2.8 4.4 44.8 0.0 11.1 11.2 12.0 9.5 8.1 8.4 1.1 7.7 5.7 10.9 4.5 UBE2H "GID3, UBC8, UBCH" ENSG00000186591 "Ubiquitin conjugating enzyme E2 H" P62256 7 129830732-129952960 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 365.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003302 Approved Approved Mitochondria NA NA 21000 "Cluster 24: B-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 44: Endometrium - Transcription" Mitochondria "HPA003302: AB_1858526" "unprognostic (1.15e-1)" "unprognostic (5.85e-2)" "unprognostic (5.67e-3)" "unprognostic (2.76e-1)" "unprognostic (2.25e-1)" "unprognostic (3.08e-2)" "unprognostic (1.13e-1)" "unprognostic (1.37e-1)" "unprognostic (9.43e-2)" "unprognostic (6.19e-2)" "prognostic unfavorable (2.33e-5)" "unprognostic (1.13e-1)" "unprognostic (3.73e-2)" "unprognostic (2.37e-1)" "unprognostic (1.12e-1)" "unprognostic (3.58e-1)" "unprognostic (1.23e-1)" 46.8 64.7 43.0 29.1 44.2 42.3 34.4 46.4 49.1 44.7 58.7 42.3 23.4 44.3 37.6 49.9 44.6 44.6 98.2 42.1 45.4 42.1 44.2 38.8 31.8 48.7 43.4 41.7 84.3 49.2 29.4 52.5 45.0 36.1 26.0 42.0 39.3 41.5 69.3 31.2 24.4 49.2 41.8 28.6 34.6 36.4 45.8 37.4 45.0 60.6 39.8 40.1 33.7 47.8 82.6 43.8 58.5 56.1 126.1 107.5 86.5 72.0 97.8 45.8 51.1 22.9 92.5 34.0 87.4 76.6 123.8 62.5 46.2 81.6 59.5 40.9 22.6 11.5 63.5 28.6 98.3 23.6 36.8 146.7 106.9 61.3 99.7 106.3 89.7 36.3 27.5 104.1 71.5 29.9 31.1 26.1 80.0 60.5 49.8 24.4 27.8 77.2 95.9 106.5 20.3 59.6 68.3 164.7 43.8 166.0 17.1 27.2 89.1 51.7 24.2 72.2 76.5 83.5 65.6 58.5 102.1 28.9 49.7 2.2 1.4 3.4 2.8 1.2 3.8 2.3 2.8 2.6 1.3 4.5 3.6 3.8 4.8 0.9 1.5 2.3 4.4 1.3 43.0 44.2 46.4 49.1 42.1 45.4 48.7 43.4 45.0 41.8 45.8 47.8 69.9 41.7 51.8 87.1 43.1 145.8 187.5 65.7 59.7 65.1 83.7 49.4 102.9 44.3 69.3 71.7 60.5 116.3 56.7 38.6 41.1 66.0 93.5 225.7 91.2 81.4 59.1 100.0 97.1 70.9 67.1 65.2 43.8 365.8 14.7 53.9 45.3 73.1 41.8 43.7 116.9 35.3 54.9 40.3 69.8 44.0 44.1 52.0 48.0 89.0 26.2 87.4 51.5 113.1 108.5 118.3 33.6 78.6 60.5 227.6 27.6 49.7 95.3 35.6 13.1 65.9 69.0 46.5 22.5 78.6 153.7 200.4 49.2 79.7 26.6 274.3 UBE3B ENSG00000151148 "Ubiquitin protein ligase E3B" Q7Z3V4 12 109477402-109536705 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041012 Approved Approved "Nuclear speckles,Mitochondria" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 51: Myeloid cells - Hemostasis" "Nuclear speckles" Mitochondria "HPA041012: AB_10964435" "unprognostic (1.53e-2)" "unprognostic (1.01e-1)" "unprognostic (7.12e-2)" "unprognostic (7.37e-2)" "unprognostic (7.43e-2)" "unprognostic (1.29e-1)" "unprognostic (4.92e-2)" "unprognostic (7.19e-2)" "unprognostic (2.93e-1)" "unprognostic (4.46e-3)" "unprognostic (9.39e-2)" "unprognostic (1.23e-1)" "prognostic favorable (2.49e-5)" "unprognostic (3.35e-1)" "unprognostic (3.35e-2)" "unprognostic (2.87e-1)" "unprognostic (1.26e-1)" 13.8 16.5 14.4 10.7 16.1 9.2 13.7 13.3 15.6 14.4 16.5 17.8 12.9 14.1 13.4 18.6 16.2 12.1 26.2 14.4 12.4 16.7 16.0 13.6 12.6 13.7 14.6 15.8 14.3 22.6 13.6 13.1 14.8 15.4 18.1 14.9 14.4 14.1 34.0 19.2 15.8 14.7 12.5 15.8 16.5 12.9 16.1 12.6 18.2 29.7 13.5 17.0 14.5 20.3 17.1 26.4 20.4 14.8 33.9 27.1 17.9 22.1 25.1 26.2 17.4 28.0 17.1 10.6 16.0 36.3 22.5 21.5 20.9 28.3 25.1 23.4 14.7 20.3 17.6 25.5 21.7 16.7 16.2 31.0 25.8 25.4 30.2 39.5 28.7 24.8 22.7 9.7 30.2 26.6 11.5 24.2 21.0 19.1 31.6 18.8 19.2 20.9 22.4 30.2 19.1 34.9 25.8 34.6 17.3 23.7 35.3 17.6 26.5 32.3 9.2 16.8 16.0 21.8 19.4 18.6 32.1 13.7 27.4 22.9 12.9 12.8 12.6 14.5 12.4 13.6 12.1 9.0 12.4 10.0 10.0 13.3 16.1 13.1 12.0 11.4 16.2 10.7 14.4 16.1 13.3 15.6 14.4 12.4 13.7 14.6 14.8 12.5 16.1 20.3 11.9 12.8 15.1 34.0 9.7 5.1 11.8 13.9 6.8 19.3 14.4 12.8 35.4 11.5 17.1 16.5 33.3 17.9 12.8 21.0 11.7 17.7 15.7 12.6 12.5 14.2 9.0 13.0 24.5 15.3 11.5 11.1 18.8 12.2 9.5 20.0 11.7 18.8 12.5 21.9 23.6 15.9 18.3 19.2 6.1 32.0 12.5 14.2 10.6 13.1 17.7 13.6 32.0 21.1 38.3 25.3 13.7 9.8 15.6 17.2 19.6 19.9 18.4 25.0 6.6 9.4 13.0 10.4 13.2 13.4 7.2 23.7 10.7 17.7 16.8 18.4 UBE3C "KIAA0010, KIAA10" ENSG00000009335 "Ubiquitin protein ligase E3C" Q15386 7 157138916-157269370 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039915 Approved Approved "Nucleoplasm,Plasma membrane,Mitochondria" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Mitochondria" "Plasma membrane" "HPA039915: AB_10795264" "unprognostic (2.83e-2)" "unprognostic (9.27e-3)" "unprognostic (2.41e-1)" "unprognostic (2.29e-1)" "unprognostic (1.19e-2)" "unprognostic (3.14e-2)" "unprognostic (1.36e-1)" "unprognostic (7.02e-2)" "unprognostic (2.34e-2)" "unprognostic (1.58e-1)" "unprognostic (3.01e-3)" "unprognostic (8.64e-2)" "prognostic favorable (9.18e-6)" "unprognostic (9.74e-2)" "unprognostic (1.86e-1)" "unprognostic (1.87e-1)" "unprognostic (3.60e-2)" 25.7 17.4 12.0 21.5 13.2 16.2 21.7 17.5 14.1 18.4 18.8 22.3 20.0 19.4 13.4 28.3 18.5 19.1 28.5 13.2 14.1 20.3 22.9 19.0 20.9 14.6 13.4 20.0 22.4 36.2 11.1 17.5 14.9 19.9 23.2 20.2 22.7 22.7 65.6 20.8 20.8 29.2 12.7 18.0 20.9 26.2 14.8 18.6 17.3 58.5 22.8 28.1 17.0 15.0 68.8 53.3 33.5 67.3 58.8 61.3 37.1 74.0 63.4 61.1 61.3 48.3 55.7 36.8 64.0 82.1 79.6 42.4 52.6 68.3 72.0 67.6 48.3 37.6 35.6 35.0 58.4 56.9 52.8 54.8 61.6 68.0 55.9 46.4 72.2 30.3 55.7 39.9 87.6 59.8 56.2 35.9 53.3 61.1 63.6 31.9 37.7 75.9 63.2 74.1 53.5 55.2 72.8 61.9 54.5 37.2 32.0 39.3 65.3 76.6 16.5 190.0 93.3 39.7 42.9 37.0 87.7 83.0 89.5 0.3 1.8 1.1 2.2 2.3 3.0 1.1 2.4 2.4 2.0 1.2 2.2 2.7 0.6 2.1 2.5 1.8 2.8 1.5 12.0 13.2 17.5 14.1 13.2 14.1 14.6 13.4 14.9 12.7 14.8 15.0 23.8 22.4 19.7 52.2 14.2 27.5 17.3 19.0 17.6 34.7 22.4 16.9 33.7 22.8 14.2 25.8 66.7 14.9 25.3 27.3 9.8 20.3 11.6 21.6 27.4 23.4 24.5 14.9 98.9 17.7 17.4 19.6 27.0 24.5 9.5 23.0 23.6 48.3 15.4 32.0 100.7 21.8 12.2 27.6 15.2 10.1 15.5 20.6 5.4 52.5 22.0 9.9 26.8 81.4 96.2 27.5 13.4 25.6 17.5 31.5 20.6 19.1 19.8 39.9 0.0 23.1 21.4 26.6 27.3 37.5 33.2 15.1 20.9 22.3 26.2 28.1 UGP2 "SVUGP2, UGP1, UGPP1" ENSG00000169764 "UDP-glucose pyrophosphorylase 2" Q16851 2 63840952-63891562 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 858.6;tongue: 756.1" "Cell type enhanced" "Detected in all" "Distal enterocytes: 849.9;Hepatocytes: 559.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 417.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034696, HPA034697, HPA064836" Enhanced Approved Nucleoplasm,Centrosome,Mitochondria NA NA 13000000 "Cluster 38: Basophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 30: Mammary glandular cells - Lactation" "Centrosome, Mitochondria" Nucleoplasm "HPA034696: AB_10670171, HPA034697: AB_2674287, HPA064836: AB_2685365" "unprognostic (1.00e-2)" "unprognostic (6.93e-2)" "unprognostic (5.12e-2)" "unprognostic (1.06e-1)" "unprognostic (2.65e-2)" "unprognostic (1.91e-1)" "prognostic favorable (2.50e-5)" "unprognostic (2.20e-1)" "unprognostic (3.01e-1)" "unprognostic (1.84e-1)" "unprognostic (1.57e-2)" "unprognostic (8.31e-2)" "unprognostic (1.03e-1)" "unprognostic (1.25e-2)" "unprognostic (3.93e-2)" "unprognostic (3.81e-1)" "unprognostic (8.44e-2)" 267.3 72.0 79.8 65.8 89.3 40.1 119.7 72.7 109.8 65.9 78.8 177.9 66.0 75.2 50.6 97.5 68.9 60.7 232.5 87.9 81.4 105.4 858.6 65.4 65.7 77.7 77.0 47.0 74.4 113.3 49.8 137.8 77.6 57.4 159.3 36.8 92.9 66.2 498.0 59.1 67.6 78.5 73.2 50.8 69.5 38.3 83.3 106.2 64.5 756.1 73.7 88.4 63.7 91.8 122.3 77.6 63.1 42.0 176.1 222.4 220.6 129.1 116.1 82.7 89.4 170.0 104.5 149.5 48.3 165.6 79.9 57.4 73.4 102.6 137.0 99.2 35.7 86.5 50.4 117.9 87.0 79.1 73.9 148.1 175.8 76.1 80.3 108.4 119.4 38.9 48.2 58.1 327.8 56.7 104.6 75.2 122.9 207.7 50.1 80.4 117.9 84.5 147.4 77.7 36.5 29.6 103.3 149.8 64.3 162.6 51.7 59.2 144.3 84.4 125.9 113.8 90.5 101.3 51.4 174.9 99.2 122.7 225.7 417.1 33.0 53.1 48.0 40.7 51.8 33.0 53.6 50.1 27.9 31.8 57.6 53.6 45.4 70.0 39.5 29.7 127.2 62.0 79.8 89.3 72.7 109.8 87.9 81.4 77.7 77.0 77.6 73.2 83.3 91.8 73.4 28.9 54.0 107.4 65.3 75.8 87.8 245.9 34.7 49.6 360.6 87.1 264.3 104.4 171.6 47.8 64.6 414.3 81.1 849.9 242.6 140.6 91.5 53.0 106.3 69.8 44.5 56.0 86.1 103.6 445.5 159.3 79.0 49.5 67.8 42.4 63.5 559.4 120.9 87.5 78.4 179.8 144.5 102.4 90.2 86.1 79.2 89.1 96.0 62.8 139.7 58.8 154.5 37.2 79.3 91.6 313.9 77.5 60.7 81.2 176.2 284.4 139.3 57.3 72.3 50.5 129.2 84.9 54.9 50.9 57.8 472.8 143.1 90.6 189.5 109.1 UGT8 CGT ENSG00000174607 "UDP glycosyltransferase 8" Q16880 4 114598770-114678225 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 266.4" "Cell type enriched" "Detected in many" 8 "Oligodendrocytes: 821.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "memory B-cell: 6.9;naive B-cell: 10.7" "Lineage enriched" "Detected in single" 12 "B-cells: 10.7" "Cell line enhanced" "Detected in many" "CAPAN-2: 58.4;OE19: 123.7;RPTEC TERT1: 55.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014405, HPA065785" Enhanced Approved Mitochondria No No "Cluster 19: B-cells - Humoral immune response" "Cluster 70: Brain - Nervous system development" "Cluster 21: OE19 - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA014405: AB_1858606, HPA065785: AB_2685559" "unprognostic (7.38e-3)" "unprognostic (2.07e-1)" "unprognostic (1.25e-2)" "unprognostic (2.38e-1)" "unprognostic (1.63e-1)" "unprognostic (1.63e-2)" "unprognostic (1.16e-2)" "unprognostic (2.38e-1)" "unprognostic (7.78e-2)" "unprognostic (1.56e-3)" "unprognostic (4.49e-2)" "unprognostic (2.76e-1)" "prognostic favorable (8.55e-5)" "unprognostic (2.80e-1)" "unprognostic (1.78e-2)" "unprognostic (7.53e-2)" "unprognostic (1.49e-1)" 0.6 0.6 58.6 4.6 153.7 1.1 4.6 166.2 94.5 7.0 9.7 26.8 30.3 3.8 0.3 1.5 4.4 11.0 0.3 66.2 94.7 31.0 0.2 1.1 4.9 220.9 132.8 0.4 8.5 0.2 0.2 0.2 200.6 0.5 27.7 2.2 7.3 0.7 0.5 2.2 27.7 1.6 139.2 1.7 16.8 5.0 132.4 0.6 13.5 0.4 5.0 0.6 0.6 266.4 0.6 0.2 4.4 0.6 0.3 0.0 0.7 0.2 0.0 0.1 3.4 17.7 58.4 17.6 1.2 0.2 13.8 25.8 0.0 0.1 0.1 0.3 14.3 0.3 24.6 0.0 0.0 0.4 0.4 0.0 0.0 0.1 0.0 5.4 0.1 0.2 16.1 3.0 0.1 0.3 0.3 1.7 6.4 123.7 8.8 1.6 28.9 0.3 55.2 0.6 31.4 4.6 0.2 5.4 0.8 1.1 0.9 5.4 1.0 1.1 19.2 0.7 19.6 6.3 0.8 0.6 29.2 0.9 17.9 0.2 0.0 0.8 0.0 0.0 0.6 6.9 0.0 0.0 0.0 10.7 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.3 58.6 153.7 166.2 94.5 66.2 94.7 220.9 132.8 200.6 139.2 132.4 266.4 0.1 6.4 1.5 1.0 22.0 0.0 1.8 0.3 6.8 0.0 5.7 6.1 0.8 8.6 3.9 25.8 0.0 0.0 0.1 19.0 9.8 1.4 9.2 9.6 1.7 0.5 48.4 0.0 1.0 13.1 0.0 0.6 19.4 21.4 0.0 0.2 0.0 0.0 0.0 0.0 3.7 27.9 0.0 0.0 0.0 3.5 1.2 0.5 1.8 2.8 0.0 0.0 0.0 98.5 821.1 10.8 14.6 0.0 4.0 0.7 24.2 1.4 1.5 0.0 0.0 0.0 0.4 20.9 34.0 5.9 0.1 0.0 0.4 0.1 26.9 0.9 ULK4 "FAM7C1, FLJ20574, REC01035" ENSG00000168038 "Unc-51 like kinase 4" Q96C45 3 41246599-41962130 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 23.4" "Cell type enhanced" "Detected in many" "Early spermatids: 352.3;Excitatory neurons: 108.6;Inhibitory neurons: 99.2;Late spermatids: 405.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA017930 Uncertain Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 18: U-2197 - ECM organization" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Mitochondria, Cytosol" "HPA017930: AB_1858615" "unprognostic (3.16e-2)" "unprognostic (2.98e-3)" "unprognostic (9.72e-3)" "unprognostic (3.46e-2)" "unprognostic (2.58e-1)" "unprognostic (8.68e-2)" "unprognostic (1.87e-1)" "unprognostic (3.50e-2)" "unprognostic (1.80e-1)" "unprognostic (1.41e-1)" "unprognostic (3.75e-3)" "unprognostic (3.43e-1)" "unprognostic (1.91e-2)" "unprognostic (5.46e-2)" "unprognostic (1.61e-1)" "unprognostic (2.53e-1)" "unprognostic (6.12e-2)" 2.7 3.1 1.6 2.9 2.1 8.5 2.5 0.4 1.7 8.5 16.9 1.6 1.2 6.6 4.5 1.5 9.0 1.9 8.6 2.3 2.5 3.9 2.1 3.5 3.0 6.9 7.6 2.1 2.0 8.0 2.9 2.7 3.9 2.2 1.7 6.0 1.7 2.4 0.4 2.1 2.0 3.5 5.6 2.0 2.4 23.4 2.5 3.0 4.9 0.4 2.7 1.9 3.7 2.1 8.3 2.9 2.8 3.8 1.1 1.7 4.8 2.7 2.7 3.2 3.0 1.0 2.3 9.5 1.6 6.3 3.5 4.1 3.7 2.1 2.9 1.5 1.0 2.1 5.7 3.3 4.1 6.5 1.8 1.6 2.3 16.1 3.2 4.4 2.2 6.4 2.1 7.5 2.3 6.4 8.1 4.9 3.4 2.1 3.4 1.7 9.1 4.5 7.2 7.6 1.6 10.3 3.1 1.3 2.8 1.8 3.1 2.0 6.6 2.0 2.4 14.2 2.5 4.5 9.0 3.9 11.5 6.3 2.5 3.7 3.7 4.0 5.0 4.3 4.1 3.7 5.3 4.5 3.3 4.7 4.0 5.7 6.6 1.8 2.3 3.3 7.7 3.0 1.6 2.1 0.4 1.7 2.3 2.5 6.9 7.6 3.9 5.6 2.5 2.1 6.4 9.6 6.9 84.9 11.2 2.0 3.0 4.0 5.2 5.6 5.7 4.6 14.8 4.3 5.1 3.7 54.2 3.1 9.9 2.0 0.0 3.4 352.3 45.3 27.4 6.0 1.8 2.1 108.6 2.4 4.1 8.7 10.2 7.5 1.3 49.6 1.8 6.6 7.3 11.8 99.2 1.2 2.0 3.1 4.0 405.2 6.5 6.9 0.0 80.6 5.9 10.4 3.1 49.8 62.0 3.0 0.7 4.1 5.1 0.9 1.1 5.9 47.3 26.7 6.6 4.4 10.5 38.9 9.6 3.3 3.7 4.2 10.8 3.6 1.9 1.2 UPP2 "UDRPASE2, UP2, UPASE2" ENSG00000007001 "Uridine phosphorylase 2" O95045 2 157876702-158136154 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "kidney: 45.8;liver: 23.9" "Cell type enhanced" "Detected in some" "Astrocytes: 24.2;Distal tubular cells: 13.7;Excitatory neurons: 32.5;Inhibitory neurons: 20.8;Oligodendrocyte precursor cells: 27.6;Proximal tubular cells: 82.1" "Cancer enriched" "Detected in some" 6 "liver cancer: 3.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA035225, HPA035226" Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Vesicles, Mitochondria" "HPA035225: AB_10604002, HPA035226: AB_10696503" "unprognostic (1.87e-1)" "unprognostic (2.33e-1)" "unprognostic (4.22e-3)" "unprognostic (1.36e-3)" "unprognostic (2.29e-1)" "unprognostic (1.55e-1)" "unprognostic (3.53e-2)" "unprognostic (5.51e-2)" "unprognostic (5.11e-2)" "unprognostic (1.23e-2)" "unprognostic (4.65e-3)" "unprognostic (2.34e-1)" "unprognostic (2.23e-2)" "unprognostic (4.89e-2)" "unprognostic (2.78e-2)" "unprognostic (1.78e-2)" "unprognostic (1.16e-2)" 0.0 0.1 3.3 0.0 2.9 0.0 0.0 1.8 3.0 0.1 1.4 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 3.7 1.9 45.8 23.9 0.0 0.1 1.3 1.3 0.3 0.1 0.0 0.2 0.0 1.1 0.0 0.0 0.9 0.4 0.0 0.0 0.3 0.1 0.0 1.4 0.0 0.0 0.1 1.6 0.0 0.2 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 2.9 1.8 3.0 3.7 1.9 1.3 1.3 1.1 1.4 1.6 2.4 0.0 0.0 0.0 24.2 0.2 0.0 0.1 0.0 0.0 1.3 0.1 0.3 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 13.7 0.0 0.1 0.2 0.1 0.1 0.0 0.0 32.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.1 8.2 0.0 0.0 20.8 0.0 0.0 0.9 0.0 0.1 0.3 0.5 0.0 2.8 0.0 0.1 0.0 27.6 3.3 0.0 0.0 0.0 0.0 0.0 0.0 82.1 0.0 1.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 UQCRFS1 "RIP1, RIS1, RISP, UQCR5" ENSG00000169021 "Ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1" P47985 19 29205320-29213151 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 231.6;tongue: 285.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1474.9;Distal tubular cells: 1035.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041863, HPA050339" Enhanced Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA041863: AB_10794638, HPA050339: AB_2681095" "unprognostic (4.00e-2)" "unprognostic (2.23e-3)" "prognostic favorable (3.29e-4)" "unprognostic (7.91e-3)" "unprognostic (3.93e-2)" "unprognostic (8.68e-2)" "unprognostic (1.84e-1)" "unprognostic (7.53e-2)" "unprognostic (3.53e-2)" "prognostic unfavorable (3.84e-4)" "unprognostic (1.73e-2)" "unprognostic (1.66e-1)" "prognostic favorable (3.92e-9)" "unprognostic (6.11e-2)" "unprognostic (2.96e-1)" "unprognostic (1.45e-1)" "unprognostic (1.92e-2)" 28.7 50.1 25.6 17.4 26.7 52.8 24.7 29.4 31.1 18.3 33.6 49.0 43.2 19.2 23.1 33.2 19.3 13.2 138.3 27.2 28.4 62.5 50.9 17.6 17.2 27.0 27.4 15.4 29.4 47.3 19.9 17.3 26.1 18.8 52.6 26.6 26.7 21.9 231.6 27.9 34.0 24.8 26.4 21.1 39.3 25.9 29.3 26.0 16.8 285.9 25.9 25.7 20.3 26.0 63.0 103.7 37.7 34.1 60.6 45.9 41.8 47.8 49.7 64.7 71.1 63.3 37.7 56.7 49.2 54.4 52.7 64.8 83.4 56.9 77.6 38.7 83.2 80.2 39.2 58.1 51.3 77.2 67.5 55.5 60.4 44.2 66.9 38.0 52.4 69.0 58.0 34.5 70.2 58.0 54.5 57.6 39.6 132.2 39.7 48.9 50.3 43.1 80.9 74.4 45.8 22.4 43.5 84.9 58.2 42.0 39.6 63.4 33.4 43.5 66.4 30.2 50.4 16.4 33.3 52.5 38.4 66.4 31.7 51.4 90.7 43.8 50.0 90.9 50.3 54.8 53.2 51.9 106.6 48.0 56.1 53.6 27.3 49.2 78.3 59.3 68.4 166.2 25.6 26.7 29.4 31.1 27.2 28.4 27.0 27.4 26.1 26.4 29.3 26.0 69.7 54.5 46.6 16.6 104.9 147.6 279.7 466.7 105.9 71.8 119.5 128.4 1474.9 161.5 201.4 114.0 16.7 282.0 116.8 321.6 1035.0 245.2 258.4 106.1 66.8 106.8 160.0 147.9 18.1 235.1 271.7 126.7 139.7 88.5 90.7 114.2 83.9 272.1 266.1 52.2 19.2 293.6 317.3 160.6 109.6 146.0 92.2 136.6 165.4 13.1 206.6 124.6 132.8 19.6 15.8 205.0 225.8 81.6 159.4 257.3 338.6 758.4 132.4 84.1 98.6 107.5 131.0 348.8 80.5 203.9 160.3 381.9 109.5 209.1 407.4 372.1 USP54 "bA137L10.3, bA137L10.4, C10orf29, FLJ37318" ENSG00000166348 "Ubiquitin specific peptidase 54" Q70EL1 10 73497538-73625994 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 134.8" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 476.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "OE19: 33.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047663, HPA063665" Approved Approved Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 70: Brain - Nervous system development" "Cluster 21: OE19 - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA047663: AB_2680116, HPA063665: " "unprognostic (2.46e-2)" "unprognostic (1.67e-1)" "unprognostic (3.17e-2)" "unprognostic (1.89e-2)" "unprognostic (2.48e-2)" "unprognostic (4.89e-3)" "unprognostic (6.63e-4)" "prognostic favorable (7.00e-4)" "unprognostic (6.24e-2)" "unprognostic (4.35e-2)" "unprognostic (8.91e-3)" "unprognostic (3.49e-1)" "unprognostic (1.95e-3)" "unprognostic (8.18e-2)" "unprognostic (6.88e-2)" "unprognostic (1.65e-2)" "unprognostic (1.31e-1)" 4.6 3.1 61.5 5.5 103.5 2.1 16.3 85.5 72.4 14.5 32.2 15.0 4.9 9.3 13.2 13.9 12.0 5.6 7.0 60.5 71.9 5.2 1.5 17.9 2.8 99.8 97.5 6.8 10.8 8.9 2.9 2.8 94.0 12.1 19.7 14.8 16.8 7.6 49.7 15.2 6.7 7.1 70.4 2.9 20.7 9.1 85.0 8.4 40.7 17.0 7.1 6.6 4.9 134.8 10.0 8.4 15.9 13.7 4.4 4.8 4.7 4.7 11.2 7.9 8.6 8.1 16.7 6.6 6.5 3.7 6.1 14.2 10.7 4.3 10.2 2.8 8.6 5.0 6.3 8.0 4.1 5.6 2.3 3.9 3.8 9.0 10.9 20.6 3.4 5.7 7.5 3.0 6.3 5.6 4.5 6.8 8.0 33.4 30.2 7.0 11.9 3.0 8.7 7.6 4.8 5.4 10.1 11.7 15.8 10.2 15.8 5.8 4.9 3.5 11.2 6.6 6.8 2.4 4.3 4.1 8.3 5.3 3.1 0.2 0.4 0.5 0.6 0.4 0.7 0.4 0.5 0.4 0.4 0.3 0.7 0.4 0.0 0.3 0.5 0.4 0.6 0.4 61.5 103.5 85.5 72.4 60.5 71.9 99.8 97.5 94.0 70.4 85.0 134.8 5.9 48.1 34.3 33.0 1.7 2.7 8.5 11.0 4.0 7.7 15.3 8.4 7.2 5.7 18.9 12.9 16.7 1.0 1.2 19.6 0.0 4.7 2.4 25.8 12.9 6.3 10.3 2.1 23.1 8.0 1.0 7.6 40.2 44.3 3.8 3.5 2.5 3.0 1.4 5.0 33.4 23.4 2.0 1.3 1.4 2.2 3.4 1.8 8.8 76.8 0.8 12.5 0.0 116.1 476.0 12.2 9.7 10.9 2.3 52.6 10.5 1.9 21.7 12.2 6.6 19.6 3.8 9.2 6.0 7.7 4.0 1.4 3.0 2.9 11.2 15.2 VARS2 "DKFZP434L1435, G7a, KIAA1885, VARS2L, VARSL" ENSG00000137411 "Valyl-tRNA synthetase 2, mitochondrial" Q5ST30 6 30914205-30926459 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062449, HPA070267" Approved Approved Mitochondria NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 72: Non-specific - Transcription" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA062449: AB_2684766, HPA070267: AB_2686245" "unprognostic (1.74e-1)" "unprognostic (8.24e-2)" "unprognostic (1.96e-3)" "unprognostic (2.50e-1)" "unprognostic (5.80e-2)" "unprognostic (3.05e-2)" "unprognostic (2.43e-2)" "unprognostic (1.66e-2)" "unprognostic (3.14e-1)" "unprognostic (8.98e-2)" "unprognostic (4.23e-2)" "unprognostic (2.60e-2)" "unprognostic (2.15e-3)" "unprognostic (1.04e-2)" "unprognostic (7.23e-2)" "unprognostic (1.19e-2)" "unprognostic (2.43e-2)" 10.2 14.4 1.3 2.1 1.5 1.9 9.7 1.5 1.6 12.5 0.4 10.5 1.2 10.4 1.5 22.5 10.1 0.2 11.1 1.4 1.3 12.5 18.9 10.5 3.1 1.3 1.6 15.3 14.0 2.3 17.1 0.9 1.4 10.2 2.2 1.4 10.9 1.1 20.9 10.1 12.8 0.7 1.2 13.4 11.7 11.8 1.3 4.1 15.0 0.2 2.3 10.5 13.2 1.3 13.8 9.6 5.5 23.1 4.9 4.4 0.7 2.2 1.9 2.5 1.6 12.6 8.9 11.9 7.5 3.0 9.4 0.0 21.3 0.0 2.4 4.6 15.7 13.2 10.2 0.9 6.7 2.3 0.3 6.2 8.1 5.9 1.3 0.9 1.3 19.5 0.1 10.5 5.4 0.0 4.6 0.0 1.7 0.0 1.2 9.1 0.0 10.3 18.3 0.0 8.5 0.2 0.2 6.6 5.4 5.0 16.3 7.4 2.2 14.2 1.4 1.0 0.1 10.0 17.1 18.8 0.0 0.6 8.7 0.0 0.0 0.0 0.3 0.1 0.4 0.3 0.1 0.3 0.2 0.1 0.1 0.1 0.0 0.0 0.2 0.3 0.2 0.1 1.3 1.5 1.5 1.6 1.4 1.3 1.3 1.6 1.4 1.2 1.3 1.3 3.0 6.4 12.5 14.7 8.0 4.0 4.9 4.7 4.0 6.6 6.4 3.7 11.6 8.6 5.5 9.2 0.0 8.7 4.1 10.1 1.9 6.7 1.5 7.7 5.2 3.9 13.1 3.4 8.3 7.1 9.6 4.8 11.7 8.6 12.7 12.9 7.5 22.5 9.2 8.4 9.1 8.4 2.0 6.9 3.5 1.6 4.1 5.1 1.8 3.7 7.9 2.8 4.1 8.0 7.2 8.9 4.7 4.1 12.3 2.3 12.4 12.5 8.9 6.0 0.0 2.9 3.7 10.4 8.0 9.0 4.1 3.4 4.8 6.9 10.9 3.8 VASN SLITL2 ENSG00000168140 Vasorin Q6EMK4 16 4371848-4383538 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 58.7;Fibroblasts: 104.2;Leydig cells: 50.1;Peritubular cells: 60.9;Sertoli cells: 98.6;Smooth muscle cells: 80.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 21.8;MCF7: 18.4;U-2197: 78.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011246, HPA016992" Uncertain Approved Nucleoplasm,Nucleoli,Mitochondria "Secreted - unknown location" NA Yes 2000000000 "Cluster 72: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria "Nucleoplasm, Nucleoli" "HPA011246: AB_1858720, HPA016992: AB_2732418" "unprognostic (2.20e-1)" "unprognostic (2.75e-1)" "unprognostic (9.22e-2)" "prognostic unfavorable (6.24e-5)" "unprognostic (2.35e-3)" "unprognostic (8.91e-3)" "unprognostic (3.15e-3)" "unprognostic (5.92e-2)" "unprognostic (2.22e-1)" "unprognostic (1.24e-2)" "unprognostic (1.08e-1)" "unprognostic (1.28e-1)" "unprognostic (1.81e-1)" "unprognostic (8.82e-3)" "unprognostic (4.23e-2)" "unprognostic (4.95e-3)" "unprognostic (5.27e-2)" 55.7 15.5 1.5 5.8 2.3 2.7 31.5 0.8 2.3 48.1 3.0 12.1 3.4 30.3 0.0 34.1 24.6 7.3 30.5 1.1 0.5 56.1 31.8 44.9 2.8 6.3 5.5 40.0 10.3 0.0 12.8 10.4 1.7 17.9 0.0 0.3 15.9 0.0 6.9 38.8 11.2 0.0 1.6 13.0 13.4 16.8 4.6 0.0 26.8 0.0 0.0 26.5 38.9 2.7 4.2 0.0 0.6 0.5 0.2 0.2 12.6 21.8 0.1 0.0 0.0 1.9 5.5 0.0 4.5 0.3 2.6 0.3 0.0 0.0 0.0 13.7 2.2 0.9 15.9 14.9 0.6 0.0 0.4 7.9 0.0 0.3 0.0 3.1 0.0 0.1 3.1 0.8 0.0 18.4 1.0 5.3 2.2 0.4 2.4 1.0 0.0 0.0 0.0 0.1 1.4 9.3 6.5 13.5 0.6 2.2 6.8 2.5 0.0 17.5 12.5 78.4 4.6 0.0 0.0 0.3 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 2.3 0.8 2.3 1.1 0.5 6.3 5.5 1.7 1.6 4.6 2.7 10.0 6.4 13.1 5.5 1.4 9.6 7.8 4.2 9.1 0.5 21.9 10.9 16.2 32.9 6.4 23.9 0.0 5.4 2.8 1.5 7.9 13.1 1.1 12.1 58.7 4.6 0.0 0.0 1.1 2.9 7.2 104.2 16.8 20.5 3.8 4.6 2.9 15.3 3.4 0.0 0.9 2.0 2.0 0.6 21.7 2.8 50.1 2.0 14.2 2.8 0.0 18.3 0.0 0.5 0.3 28.3 1.2 60.9 0.8 6.4 0.2 12.3 2.7 0.7 98.6 12.6 80.9 0.8 4.1 3.7 7.5 10.0 3.5 2.3 0.8 4.9 VPS26C "DCRA, DSCR3" ENSG00000157538 "VPS26 endosomal protein sorting factor C" O14972 21 37223420-37267919 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 26.4;Exocrine glandular cells: 28.0;Extravillous trophoblasts: 26.4;Hofbauer cells: 32.7;Pancreatic endocrine cells: 33.2;Proximal tubular cells: 29.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023288 Uncertain Approved Mitochondria NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA023288: AB_1847872" "unprognostic (1.01e-3)" "unprognostic (6.42e-2)" "unprognostic (7.96e-3)" "unprognostic (2.15e-2)" "unprognostic (4.10e-3)" "unprognostic (2.04e-1)" "unprognostic (1.88e-2)" "unprognostic (1.40e-1)" "unprognostic (3.15e-1)" "unprognostic (7.76e-2)" "unprognostic (5.40e-2)" "unprognostic (1.97e-1)" "prognostic favorable (8.54e-4)" "unprognostic (1.72e-1)" "unprognostic (3.24e-1)" "unprognostic (5.24e-2)" "unprognostic (3.16e-1)" 19.8 24.5 14.8 18.5 16.1 21.4 15.8 16.8 15.8 16.3 15.9 26.6 28.0 14.8 11.4 21.2 13.8 19.6 24.9 14.4 15.6 32.9 29.5 22.1 22.6 16.1 15.9 17.4 22.6 17.7 8.6 21.4 16.6 14.3 26.0 13.6 16.9 15.8 31.5 15.7 26.9 19.9 16.2 20.2 21.2 7.5 16.5 28.1 18.1 37.8 23.6 21.9 14.2 17.6 31.8 13.8 30.2 26.5 55.4 49.4 34.3 29.9 66.2 26.6 40.2 19.2 32.7 22.0 11.7 70.0 63.9 15.0 32.6 32.1 26.1 52.8 23.5 37.6 13.6 18.7 49.1 27.8 24.3 43.5 31.2 31.0 50.4 48.1 51.4 40.5 24.0 46.8 52.5 14.1 47.2 23.7 34.4 48.7 13.8 44.8 14.5 32.5 32.8 23.7 24.4 32.6 20.6 40.9 65.5 39.0 38.4 22.0 41.0 30.6 10.8 33.2 18.5 71.3 78.0 30.3 48.3 47.9 35.2 58.6 48.6 84.9 50.7 60.5 46.8 37.5 43.1 45.4 47.7 29.4 39.8 41.0 50.1 52.9 55.7 19.4 54.9 54.1 14.8 16.1 16.8 15.8 14.4 15.6 16.1 15.9 16.6 16.2 16.5 17.6 18.1 9.6 21.9 0.0 4.3 0.0 0.0 0.0 0.0 0.0 14.5 13.3 0.0 0.0 6.8 9.2 0.0 16.0 23.8 0.0 21.5 26.4 0.0 12.5 12.7 8.4 0.0 0.0 0.0 28.0 26.4 5.4 0.0 16.1 8.8 19.0 0.0 0.0 32.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.3 0.0 0.0 16.5 0.0 0.0 0.0 0.0 33.2 0.0 0.0 3.1 0.0 0.0 29.7 4.4 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 14.6 8.5 10.1 0.0 0.0 VPS35L "C16orf62, MGC16824" ENSG00000103544 "VPS35 endosomal protein sorting factor like" Q7Z3J2 16 19555240-19706793 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 32.4;Cytotrophoblasts: 29.4;Distal tubular cells: 29.4;Hofbauer cells: 44.9;Syncytiotrophoblasts: 40.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042969, HPA053547" Uncertain Approved Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA042969: AB_10794920, HPA053547: AB_2682183" "unprognostic (7.15e-2)" "unprognostic (6.54e-2)" "unprognostic (1.17e-1)" "unprognostic (7.20e-2)" "unprognostic (1.51e-1)" "unprognostic (2.67e-1)" "unprognostic (1.15e-1)" "unprognostic (2.74e-1)" "unprognostic (2.52e-1)" "unprognostic (1.22e-3)" "unprognostic (3.57e-2)" "unprognostic (2.06e-1)" "prognostic favorable (1.31e-8)" "unprognostic (1.82e-3)" "unprognostic (8.92e-2)" "unprognostic (5.08e-2)" "unprognostic (1.13e-2)" 19.3 22.7 23.3 15.9 33.5 13.2 17.1 21.8 24.9 21.2 11.7 19.2 13.7 20.1 22.4 16.8 19.2 17.5 17.8 20.7 23.5 22.2 14.4 16.2 14.6 23.3 24.4 23.3 16.5 35.6 20.4 20.2 24.6 15.9 19.4 16.1 12.4 18.9 22.2 13.8 15.3 25.1 20.5 17.2 13.3 31.5 28.0 16.1 22.7 25.2 16.6 18.3 15.6 40.3 22.3 37.5 35.7 28.4 44.2 60.1 5.8 32.5 52.3 33.9 38.9 6.4 37.0 27.1 67.4 51.7 0.2 6.2 27.5 16.7 36.5 1.6 15.7 16.4 32.6 0.6 57.4 25.9 31.6 43.9 24.4 31.7 21.5 48.2 54.4 13.2 22.3 6.2 55.7 15.7 23.0 7.2 24.8 3.9 5.1 19.6 11.7 7.1 38.6 5.2 21.8 22.1 43.7 1.5 18.6 27.2 12.9 22.2 61.0 17.4 16.2 25.7 3.7 23.8 45.2 10.6 33.6 21.1 27.5 26.5 35.3 16.5 18.9 42.0 23.5 14.7 18.0 18.8 42.6 23.5 21.0 18.6 4.2 37.6 37.7 11.5 21.6 28.5 23.3 33.5 21.8 24.9 20.7 23.5 23.3 24.4 24.6 20.5 28.0 40.3 32.4 6.4 16.4 0.0 3.0 0.0 0.0 0.0 0.0 0.0 9.5 9.1 0.0 0.0 8.1 16.5 0.0 29.4 5.0 0.0 29.4 20.4 0.0 8.2 15.8 15.5 0.0 0.0 0.0 17.0 19.5 8.1 0.0 11.1 3.8 18.1 0.0 0.0 44.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 10.5 0.0 0.0 1.2 0.0 0.0 21.9 2.9 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 40.2 3.4 21.0 0.0 0.0 VWA5B1 FLJ32784 ENSG00000158816 "Von Willebrand factor A domain containing 5B1" Q5TIE3 1 20290919-20354894 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.3;choroid plexus: 19.1" "Cell type enhanced" "Detected in some" "Astrocytes: 2.6;Early spermatids: 10.9;Inhibitory neurons: 1.8;Late spermatids: 9.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 10 "SCLC-21H: 1.2" "Low region specificity" "Detected in many" "HPA027496, HPA028405, HPA064829" Enhanced Approved "Plasma membrane,Mitochondria,Cytosol" "Secreted in male reproductive system" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 23: Spermatids - Flagellum & Golgi organization" Mitochondria "Plasma membrane, Cytosol" "HPA027496: AB_10599853, HPA028405: AB_10600992, HPA064829: AB_2685363" "unprognostic (2.34e-1)" "unprognostic (2.91e-1)" "unprognostic (7.78e-2)" "unprognostic (1.16e-2)" "unprognostic (4.73e-2)" "unprognostic (1.21e-2)" "unprognostic (1.09e-1)" "unprognostic (1.86e-2)" "unprognostic (4.39e-2)" "unprognostic (1.73e-1)" "unprognostic (5.41e-4)" "unprognostic (7.43e-4)" "unprognostic (1.82e-2)" "unprognostic (3.33e-2)" "unprognostic (1.03e-1)" 0.0 0.4 0.8 0.1 0.9 0.0 0.0 0.1 0.1 0.0 19.1 0.0 0.0 0.0 1.3 0.0 0.3 0.2 0.0 1.1 2.9 1.3 0.0 0.1 0.1 3.7 6.3 0.0 0.0 1.1 2.9 0.1 5.1 0.0 0.0 0.1 1.7 0.3 0.0 0.0 0.0 0.0 1.5 0.0 0.0 3.2 3.0 0.0 0.2 0.4 0.0 0.4 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.9 0.1 0.1 1.1 2.9 3.7 6.3 5.1 1.5 3.0 0.7 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 9.0 0.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 WDR26 "FLJ21016, GID7" ENSG00000162923 "WD repeat domain 26" Q9H7D7 1 224385146-224437033 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 243.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028538, HPA028539, HPA061094" Enhanced Enhanced Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 6: T47d - Mammary gland" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Cytosol" Mitochondria "HPA028538: , HPA028539: AB_10669752, HPA061094: AB_2684427" "unprognostic (4.09e-3)" "unprognostic (1.29e-1)" "unprognostic (1.22e-1)" "unprognostic (1.31e-2)" "unprognostic (6.67e-2)" "unprognostic (2.27e-1)" "unprognostic (1.24e-1)" "unprognostic (1.64e-1)" "unprognostic (8.42e-2)" "unprognostic (6.32e-2)" "unprognostic (5.59e-2)" "unprognostic (4.18e-1)" "prognostic unfavorable (3.31e-6)" "unprognostic (8.40e-3)" "unprognostic (4.00e-1)" "unprognostic (2.17e-1)" "unprognostic (2.28e-1)" 33.7 28.3 21.9 32.1 21.3 88.9 26.7 20.0 22.0 28.9 27.5 28.9 21.2 26.5 20.8 52.1 22.7 27.1 28.0 23.4 22.8 23.7 35.4 35.1 33.8 21.5 22.0 24.3 24.4 26.4 20.6 35.6 20.2 26.1 25.4 31.5 28.7 25.0 57.1 40.9 26.5 28.6 18.8 38.2 26.7 37.4 22.1 36.0 26.0 45.0 33.2 32.6 31.5 21.9 49.7 28.0 54.6 29.7 76.8 74.6 47.6 58.4 86.4 51.7 48.0 39.0 46.8 51.9 74.4 86.3 21.7 40.6 40.2 47.2 76.1 55.3 53.6 36.2 31.5 31.0 74.7 40.3 68.6 70.8 58.4 55.0 52.1 72.6 80.8 31.7 52.7 51.4 62.4 24.8 42.4 34.7 65.7 41.5 32.0 42.6 66.1 44.2 55.1 48.3 29.5 56.0 64.8 94.9 74.9 55.5 117.5 67.0 88.7 47.7 28.7 41.5 71.3 66.8 33.6 35.2 53.3 26.1 66.8 2.1 1.0 2.1 1.4 1.4 0.8 0.8 0.8 1.0 0.9 0.6 0.7 1.0 4.8 1.5 2.4 1.0 1.1 0.8 21.9 21.3 20.0 22.0 23.4 22.8 21.5 22.0 20.2 18.8 22.1 21.9 32.6 105.8 54.2 55.2 34.4 111.4 29.6 30.9 43.3 24.6 54.1 30.5 49.2 40.0 48.2 35.0 31.3 30.4 54.3 34.8 5.9 22.2 243.3 60.6 35.2 44.2 35.4 53.7 63.4 23.8 15.7 37.9 26.5 71.0 48.1 34.1 41.4 44.2 53.4 38.7 61.3 44.4 40.7 133.4 96.4 102.1 37.0 74.5 46.2 67.5 45.7 16.3 32.0 63.3 70.0 34.2 26.2 28.2 33.0 49.0 19.2 22.8 55.4 24.2 19.7 35.2 41.4 37.1 25.8 63.9 122.3 68.3 45.1 37.9 25.0 63.7 WDR70 FLJ10233 ENSG00000082068 "WD repeat domain 70" Q9NW82 5 37379285-37753435 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 177.2;Inhibitory neurons: 166.2;Oligodendrocyte precursor cells: 153.3;Oligodendrocytes: 168.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043064, HPA048149" Uncertain Approved Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 52: Non-specific - Ribosome" "Cluster 20: HeLa - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Mitochondria, Cytosol" "HPA043064: , HPA048149: AB_2680287" "unprognostic (2.55e-2)" "unprognostic (3.39e-3)" "unprognostic (8.87e-2)" "prognostic unfavorable (4.34e-4)" "unprognostic (4.40e-2)" "unprognostic (1.38e-2)" "unprognostic (1.20e-3)" "unprognostic (1.17e-2)" "prognostic unfavorable (3.73e-4)" "unprognostic (6.34e-2)" "unprognostic (8.36e-2)" "unprognostic (9.75e-2)" "unprognostic (1.18e-2)" "unprognostic (1.69e-1)" "unprognostic (9.31e-2)" "unprognostic (1.22e-1)" "unprognostic (8.11e-2)" 9.2 6.2 3.6 7.4 4.4 12.6 10.5 8.2 5.0 9.3 4.7 9.1 7.1 11.5 8.6 8.1 8.9 6.8 7.8 3.4 4.8 7.3 8.0 8.2 10.4 5.1 4.3 10.8 8.4 9.4 4.0 9.5 5.2 8.4 9.3 5.2 7.5 8.8 15.4 8.8 8.2 10.6 3.5 9.5 7.8 8.8 5.0 11.8 8.9 11.1 10.8 8.6 7.9 6.7 17.8 11.5 22.7 28.9 22.8 22.4 31.2 21.6 21.9 26.3 21.6 19.5 17.9 28.7 12.7 21.6 19.8 16.4 19.4 21.7 27.9 27.5 24.5 21.5 34.3 13.9 17.6 37.4 18.5 21.8 15.8 19.9 26.9 19.8 21.5 21.7 27.2 11.5 16.7 12.2 23.8 18.6 15.4 14.7 21.4 27.2 56.1 29.9 13.3 21.0 19.5 18.3 73.6 16.3 16.6 17.0 21.0 23.3 23.8 22.7 21.6 22.2 17.8 15.3 24.1 32.9 15.1 33.3 19.2 8.1 16.5 15.0 9.7 20.7 10.5 13.4 11.2 10.6 17.9 14.8 11.0 10.5 3.7 14.0 19.5 18.4 12.0 8.3 3.6 4.4 8.2 5.0 3.4 4.8 5.1 4.3 5.2 3.5 5.0 6.7 23.7 32.1 29.1 103.2 25.1 9.2 13.7 15.4 12.5 37.2 23.3 17.5 18.6 17.2 14.4 9.2 37.5 27.1 33.6 18.3 19.6 18.3 20.1 16.9 36.4 17.7 13.8 17.7 177.2 20.7 26.7 17.9 15.8 20.1 19.7 22.8 22.5 25.7 18.9 25.2 166.2 21.5 14.2 25.8 6.4 7.0 29.5 21.2 12.4 113.4 31.3 16.4 30.9 153.3 168.6 16.1 17.0 22.6 21.5 6.9 16.1 21.2 20.8 52.2 13.1 20.0 21.7 42.7 25.2 11.9 7.7 22.2 20.2 17.3 22.1 8.7 WSB1 "DKFZp564A122, DKFZp564B0482, SWIP1" ENSG00000109046 "WD repeat and SOCS box containing 1" Q9Y6I7 17 27294076-27315926 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003293 Approved Approved Mitochondria NA Yes "Cluster 45: Eosinophils - Innate immune response" "Cluster 19: Lung - Lung function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 41: Macrophages - Immune response" Mitochondria "HPA003293: AB_1858863" "unprognostic (1.73e-1)" "unprognostic (5.13e-2)" "unprognostic (1.25e-1)" "unprognostic (1.44e-1)" "unprognostic (2.14e-1)" "unprognostic (2.66e-1)" "prognostic unfavorable (4.07e-5)" "unprognostic (2.59e-2)" "unprognostic (5.40e-3)" "unprognostic (2.74e-1)" "unprognostic (9.22e-2)" "unprognostic (1.69e-2)" "prognostic unfavorable (1.02e-7)" "unprognostic (1.44e-1)" "unprognostic (3.18e-1)" "unprognostic (1.62e-1)" "unprognostic (3.74e-2)" 41.9 22.1 14.1 45.9 35.7 48.7 35.7 22.9 26.9 47.0 5.2 40.7 28.6 49.4 24.6 27.7 45.9 39.6 32.5 14.1 35.9 29.0 15.6 58.3 34.5 38.7 22.7 47.7 29.6 19.0 23.8 75.0 40.6 27.6 30.9 76.0 27.4 32.1 23.0 23.2 33.7 44.8 17.0 69.9 32.7 21.6 33.2 24.8 28.8 16.1 35.2 32.8 39.1 80.0 30.8 21.3 65.3 37.5 40.3 49.7 69.7 26.6 37.9 20.6 39.6 32.0 12.2 30.6 29.6 36.6 26.2 28.4 40.0 19.6 30.9 85.3 33.1 48.7 41.9 32.7 75.7 34.1 69.2 60.2 26.3 30.1 18.4 31.5 83.1 31.7 49.8 28.6 36.9 19.4 44.4 38.4 19.4 17.1 17.3 35.5 35.9 18.5 31.1 24.6 20.9 28.8 27.8 27.3 36.7 77.8 22.1 44.5 46.5 25.3 19.2 34.8 26.4 12.8 34.9 31.2 23.9 26.8 23.4 75.0 41.1 71.5 21.6 70.3 26.1 22.1 18.1 24.2 65.5 25.3 17.0 19.7 37.1 21.4 82.5 21.5 30.2 26.4 14.1 35.7 22.9 26.9 14.1 35.9 38.7 22.7 40.6 17.0 33.2 80.0 300.4 221.2 476.1 189.7 245.4 249.2 185.6 138.4 253.8 91.9 186.7 147.7 67.5 144.4 194.2 239.1 348.2 360.7 183.2 222.7 27.4 124.9 153.0 201.2 187.6 254.9 194.4 148.1 229.5 65.1 217.2 284.6 190.6 301.5 163.5 436.3 316.6 43.3 228.2 82.4 267.8 191.5 162.8 412.6 288.9 26.6 141.4 358.9 197.5 206.1 153.2 170.5 112.3 349.3 658.2 76.7 185.4 122.6 144.9 196.3 178.7 30.7 137.5 381.4 124.9 243.8 221.9 119.6 104.8 202.2 280.3 714.5 183.9 98.5 133.6 148.9 XK "Kx, NA, NAC, X1k, XKR1" ENSG00000047597 "X-linked Kx blood group" P51811 X 37685791-37732130 "Blood group antigen proteins, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Blood group antigen" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.2;intestine: 12.2;stomach 1: 11.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 26.7;Erythroid cells: 63.5;Gastric mucus-secreting cells: 17.9;Proximal enterocytes: 21.5;Undifferentiated cells: 14.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 6.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 53 "basophil: 10.2;eosinophil: 5.8" "Lineage enriched" "Detected in single" 102 "granulocytes: 10.2" "Cell line enhanced" "Detected in many" "HEL: 44.4;HL-60: 23.2;K-562: 29.1;NB-4: 21.1;RPMI-8226: 20.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019036 Approved Approved Nucleoplasm,Vesicles,Mitochondria No No "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" Mitochondria "Nucleoplasm, Vesicles" "HPA019036: AB_1846286" "unprognostic (2.37e-2)" "unprognostic (7.13e-3)" "unprognostic (5.03e-2)" "unprognostic (1.00e-2)" "unprognostic (7.97e-2)" "unprognostic (4.56e-1)" "unprognostic (3.59e-2)" "unprognostic (4.00e-2)" "unprognostic (4.77e-3)" "unprognostic (5.07e-2)" "unprognostic (6.63e-2)" "unprognostic (5.90e-2)" "unprognostic (4.44e-8)" "unprognostic (1.74e-1)" "unprognostic (4.75e-2)" "unprognostic (1.06e-1)" "unprognostic (1.43e-1)" 0.2 2.1 2.5 1.4 2.5 14.2 0.7 2.3 3.0 1.2 0.2 12.2 10.8 0.7 0.5 2.0 3.8 0.9 4.3 3.2 4.9 0.9 0.8 1.0 0.2 1.6 0.9 0.7 4.9 0.7 1.3 0.7 2.0 1.5 11.2 2.1 1.2 0.9 5.4 0.7 10.6 1.8 0.5 0.5 11.5 1.4 2.8 0.2 0.9 5.8 0.5 1.1 0.8 1.4 17.4 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 14.7 0.3 0.0 0.8 2.7 15.4 0.1 0.0 0.0 4.2 44.4 2.4 0.0 0.0 23.2 3.5 0.0 0.8 0.0 0.0 0.0 0.0 0.0 29.1 10.9 0.1 1.7 0.2 21.1 5.5 0.7 5.6 0.0 0.0 20.2 0.0 1.1 4.1 0.1 0.8 1.4 0.1 0.9 2.1 5.6 0.0 0.0 0.8 0.0 2.4 9.3 16.5 0.0 0.2 12.1 0.1 10.2 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 2.5 2.5 2.3 3.0 3.2 4.9 1.6 0.9 2.0 0.5 2.8 1.4 0.0 0.0 1.1 2.6 0.8 0.4 0.4 0.1 1.2 0.7 1.1 0.8 7.9 0.0 0.1 0.0 6.2 0.3 0.1 26.7 0.0 0.0 1.2 4.0 0.1 0.3 6.1 63.5 11.0 3.1 0.1 0.6 17.9 0.9 0.0 0.1 0.0 0.9 0.1 3.3 12.6 10.9 2.0 0.3 0.0 0.4 0.0 0.2 1.8 1.9 0.0 0.0 0.0 4.5 1.2 1.1 9.2 0.7 2.2 0.9 21.5 0.1 1.7 1.4 0.0 0.7 1.3 10.2 6.1 3.8 1.1 0.0 0.3 0.1 14.7 1.5 XKR9 ENSG00000221947 "XK related 9" Q5GH70 8 70669339-70790371 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 5.3;testis: 7.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 42.0;Inhibitory neurons: 17.9;Oligodendrocytes: 23.0;Spermatocytes: 82.3;Spermatogonia: 19.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 3.3;hTCEpi: 6.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA044430 Enhanced Approved Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 45: Intestine - Brush border" "Cluster 30: Epithelial cell lines - Translation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Mitochondria "HPA044430: AB_10961283" "unprognostic (1.79e-2)" "unprognostic (7.31e-2)" "unprognostic (1.42e-1)" "unprognostic (1.40e-3)" "unprognostic (1.85e-1)" "unprognostic (1.22e-1)" "unprognostic (2.23e-2)" "unprognostic (9.33e-2)" "unprognostic (1.63e-1)" "unprognostic (2.63e-2)" "prognostic unfavorable (7.20e-4)" "unprognostic (2.29e-1)" "unprognostic (6.96e-6)" "unprognostic (3.65e-1)" "unprognostic (3.26e-1)" "unprognostic (4.04e-3)" "unprognostic (3.71e-2)" 0.2 1.1 0.5 0.4 0.5 0.5 0.4 0.0 1.6 0.2 0.0 0.9 2.6 0.2 1.3 0.5 0.1 2.2 0.2 0.5 0.3 0.5 3.3 0.6 0.5 0.6 0.2 0.2 0.3 0.1 0.6 0.4 1.1 0.6 0.5 2.4 0.5 0.0 0.2 0.9 5.3 0.3 0.0 0.5 1.8 7.7 0.3 0.5 0.4 0.3 0.5 1.0 0.2 1.5 2.3 0.1 0.5 0.2 0.0 0.5 0.3 0.9 0.4 0.3 0.9 3.3 0.2 0.3 1.5 0.0 1.1 0.1 0.0 0.5 1.1 0.4 0.3 0.2 0.2 0.2 0.0 0.7 1.2 0.6 6.4 0.1 0.0 0.2 0.0 1.6 0.1 2.3 0.1 0.3 0.4 0.3 1.3 0.1 0.4 0.3 0.6 0.1 0.1 1.7 1.4 0.2 0.4 1.0 0.3 0.1 0.3 0.1 0.2 0.3 0.6 0.4 0.3 2.0 0.5 1.5 0.1 0.2 0.2 0.2 0.0 0.0 0.2 0.0 0.4 0.2 0.4 0.2 0.0 0.2 0.6 0.4 0.1 0.2 0.0 0.0 0.8 0.0 0.5 0.5 0.0 1.6 0.5 0.3 0.6 0.2 1.1 0.0 0.3 1.5 0.1 6.4 2.2 14.4 1.1 2.7 3.5 3.9 4.6 2.2 0.7 1.0 0.4 1.5 3.3 0.0 8.4 1.0 0.3 1.4 0.0 1.6 5.3 0.5 0.3 0.6 0.0 0.0 42.0 4.6 0.6 0.8 6.1 0.6 0.0 0.3 0.0 2.3 0.3 1.7 17.9 3.4 0.0 0.3 0.4 4.9 0.9 0.2 0.0 1.9 0.0 1.5 2.1 1.5 23.0 6.0 1.3 0.4 0.8 1.7 11.7 0.5 3.2 5.3 0.0 0.1 0.2 82.3 19.7 0.5 0.9 1.0 1.0 0.1 0.4 2.3 YIPF2 "FinGER2, MGC3262" ENSG00000130733 "Yip1 domain family member 2" Q9BWQ6 19 10922185-10928681 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 159.1;Syncytiotrophoblasts: 174.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019902 Approved Approved "Golgi apparatus,Mitochondria" No No "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 66: Spermatocytes - Spermatogenesis" "Golgi apparatus, Mitochondria" "HPA019902: AB_1858925" "unprognostic (1.27e-1)" "unprognostic (8.56e-2)" "unprognostic (2.90e-3)" "unprognostic (8.38e-2)" "unprognostic (3.66e-1)" "unprognostic (3.96e-1)" "unprognostic (1.93e-1)" "unprognostic (7.65e-2)" "unprognostic (4.30e-2)" "unprognostic (5.62e-3)" "unprognostic (1.13e-1)" "unprognostic (1.51e-1)" "unprognostic (1.06e-1)" "unprognostic (3.28e-2)" "unprognostic (3.92e-2)" "unprognostic (5.99e-2)" "unprognostic (2.00e-2)" 29.5 43.5 18.1 15.9 18.7 29.6 34.1 20.5 26.6 41.7 30.7 34.7 31.8 38.1 26.8 51.0 35.2 30.3 31.6 19.4 20.3 45.1 56.1 32.8 16.8 22.4 19.6 39.6 114.3 33.4 108.2 38.9 21.0 40.3 15.8 6.5 105.7 23.6 24.8 33.8 29.9 14.2 18.2 27.7 39.2 76.8 19.4 14.3 47.5 10.3 11.2 32.6 39.6 20.4 64.9 22.3 17.5 25.4 40.0 38.9 30.1 48.9 71.6 36.6 52.9 68.1 51.6 12.8 80.2 56.2 16.7 49.8 11.9 47.6 9.5 41.7 43.2 24.2 27.3 39.1 62.1 42.5 49.3 35.7 33.6 24.7 35.4 47.7 26.2 31.1 31.6 69.2 22.9 109.4 27.4 42.7 29.4 44.3 55.2 22.8 14.1 65.3 33.0 30.2 45.4 22.2 35.2 56.4 48.8 15.3 51.7 60.1 39.1 41.6 15.3 60.2 36.7 96.7 42.5 24.2 65.1 72.9 43.9 39.2 18.8 9.3 13.3 21.3 10.4 16.3 10.4 12.3 22.3 9.5 9.3 13.3 3.1 12.1 19.4 34.1 12.6 10.4 18.1 18.7 20.5 26.6 19.4 20.3 22.4 19.6 21.0 18.2 19.4 20.4 20.5 16.0 21.2 2.6 16.0 6.8 41.6 22.4 17.1 19.4 46.9 37.8 0.5 27.1 27.3 35.0 16.7 109.5 20.6 31.9 27.4 69.3 131.1 23.0 20.1 19.2 43.3 17.2 6.4 80.7 114.1 36.0 33.6 29.3 21.6 22.5 22.5 23.0 38.7 18.5 6.7 69.4 14.2 15.3 5.2 34.6 35.1 20.5 5.4 5.6 21.1 23.8 16.5 3.5 3.3 50.3 47.7 25.6 55.4 51.6 52.5 27.0 26.1 16.4 6.6 20.0 21.9 159.1 16.6 22.6 7.0 174.3 13.9 27.9 50.6 50.0 YJEFN3 "FLJ44968, hYjeF_N3-19p13.11" ENSG00000250067 "YjeF N-terminal domain containing 3" A6XGL0 19 19528861-19537581 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 50.4;testis: 24.3" "Cell type enriched" "Detected in many" 4 "Late spermatids: 605.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 10.3;HEK 293: 12.1" HPA060789 Enhanced Approved Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 10: Brain - Neuronal signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "HPA060789: AB_2684366" "unprognostic (2.59e-2)" "unprognostic (2.50e-1)" "unprognostic (5.99e-6)" "unprognostic (1.65e-1)" "unprognostic (3.16e-1)" "unprognostic (2.28e-2)" "unprognostic (4.37e-4)" "unprognostic (2.38e-1)" "unprognostic (1.04e-2)" "unprognostic (1.06e-1)" "prognostic favorable (7.25e-4)" "unprognostic (2.11e-2)" "prognostic unfavorable (1.30e-7)" "unprognostic (1.17e-2)" "unprognostic (8.26e-2)" "unprognostic (2.48e-1)" "unprognostic (9.49e-3)" 0.4 0.4 22.1 0.4 46.0 0.0 0.3 0.2 38.9 0.4 1.2 0.6 0.1 0.3 2.7 0.3 0.8 0.1 1.8 50.4 15.3 2.2 0.9 0.4 0.4 10.6 5.4 0.7 0.6 0.1 4.3 0.3 6.1 1.9 0.4 0.5 0.2 0.3 0.5 1.3 0.4 0.2 0.8 0.9 0.6 24.3 6.6 0.2 1.0 0.1 0.3 0.6 0.4 9.7 0.2 0.8 1.7 0.7 0.2 0.4 10.3 0.6 0.1 0.4 0.6 0.8 0.6 0.5 1.4 0.1 0.1 1.1 0.2 0.2 0.0 0.1 12.1 0.0 1.8 0.0 0.1 0.2 0.5 0.1 0.5 0.2 0.4 0.1 0.0 0.7 0.8 0.6 0.0 0.9 0.0 0.1 3.3 0.0 2.5 1.9 0.4 0.3 0.0 0.1 0.2 2.8 0.2 0.0 0.3 0.5 1.2 1.4 0.7 0.3 0.8 3.2 0.8 2.7 2.2 0.6 0.2 1.6 0.3 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.2 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.4 0.0 22.1 46.0 0.2 38.9 50.4 15.3 10.6 5.4 6.1 0.8 6.6 9.7 2.7 9.6 0.5 11.8 2.3 2.0 2.2 1.8 0.6 19.7 3.2 3.2 1.9 1.5 4.4 0.0 10.4 1.6 2.3 6.2 1.9 1.8 136.4 2.6 4.0 2.5 5.4 4.4 22.4 0.6 1.1 2.4 5.6 5.5 1.3 4.0 1.4 1.8 1.1 10.1 29.0 6.7 0.0 0.6 2.0 605.2 3.7 2.0 1.8 5.6 1.4 5.1 3.1 3.5 6.3 0.7 2.6 1.9 0.7 2.4 4.4 0.5 2.3 17.2 6.6 7.5 3.8 16.1 13.2 0.7 4.1 1.8 2.8 0.9 6.0 1.2 YKT6 ENSG00000106636 "YKT6 v-SNARE homolog" O15498 7 44200959-44214294 "Metabolic proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030817, HPA030818" Approved Approved Mitochondria,Cytosol No No 23000 "Cluster 26: Non-specific - Mitochondria" "Cluster 70: Brain - Nervous system development" "Cluster 17: WM-115 - Nervous system development" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol Mitochondria "HPA030817: AB_10599828, HPA030818: AB_10602102" "unprognostic (1.25e-1)" "unprognostic (7.35e-3)" "unprognostic (1.30e-3)" "unprognostic (7.80e-3)" "unprognostic (7.45e-3)" "prognostic unfavorable (4.64e-4)" "prognostic unfavorable (1.02e-4)" "unprognostic (3.14e-2)" "unprognostic (2.03e-1)" "unprognostic (8.77e-3)" "unprognostic (1.99e-1)" "unprognostic (1.17e-1)" "unprognostic (8.65e-2)" "unprognostic (1.63e-1)" "unprognostic (2.01e-2)" "unprognostic (1.34e-2)" "unprognostic (7.66e-3)" 31.6 33.4 52.4 31.7 51.8 36.9 26.4 50.8 52.2 23.5 46.3 34.9 30.5 30.3 38.7 50.1 22.8 19.9 37.8 53.9 57.8 33.7 20.2 27.7 27.6 56.1 62.8 19.5 52.6 34.3 31.7 27.7 60.2 27.2 34.5 16.0 37.6 27.1 49.6 34.3 29.7 35.0 57.2 30.2 40.4 28.4 58.7 38.4 28.8 36.5 34.9 31.2 24.7 56.5 81.9 86.1 71.3 94.8 85.3 72.6 63.1 161.5 130.3 104.5 103.6 93.7 75.9 88.0 71.4 157.7 184.5 94.5 83.1 111.0 140.8 89.4 65.3 53.7 63.1 58.7 105.1 103.4 80.8 66.7 97.6 114.7 123.4 77.5 111.5 75.9 126.2 64.8 125.2 79.4 87.3 106.8 178.8 111.5 120.2 81.9 76.0 68.4 72.2 69.2 94.2 151.6 83.0 126.4 97.8 115.8 100.0 100.4 138.0 112.5 123.9 104.2 199.1 134.5 187.8 130.3 146.2 87.5 219.4 5.6 10.8 18.2 5.3 11.5 7.9 7.1 7.0 9.0 10.0 10.1 5.4 5.4 8.9 5.1 10.6 7.9 7.5 5.5 52.4 51.8 50.8 52.2 53.9 57.8 56.1 62.8 60.2 57.2 58.7 56.5 12.4 12.8 9.4 9.1 16.2 26.0 18.1 14.1 10.2 8.4 21.6 15.4 19.7 7.2 13.7 20.2 10.4 25.3 13.9 45.4 25.4 47.1 25.4 9.4 15.8 19.3 13.8 9.5 7.0 83.0 63.5 18.7 18.8 17.7 1.3 15.1 14.6 15.7 41.2 13.5 6.5 26.6 16.2 19.4 19.3 8.3 9.9 19.5 26.6 1.0 40.2 11.0 23.7 8.0 8.3 79.0 23.3 13.5 38.8 35.8 33.1 23.1 8.7 7.9 0.0 13.1 23.8 18.9 23.0 22.9 25.9 49.3 15.2 11.8 24.0 44.4 YRDC "FLJ23476, IRIP, SUA5" ENSG00000196449 "YrdC N6-threonylcarbamoyltransferase domain containing" Q86U90 1 37802945-37808208 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 50.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 77.8;Prostatic glandular cells: 87.8;Urothelial cells: 92.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "basophil: 8.8" "Lineage enriched" "Detected in many" 8 "granulocytes: 8.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030147 Approved Approved Mitochondria NA NA "Cluster 34: Basophils - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" Mitochondria "HPA030147: AB_10603327" "unprognostic (2.98e-2)" "unprognostic (6.29e-2)" "unprognostic (1.36e-3)" "unprognostic (2.08e-3)" "unprognostic (2.03e-1)" "unprognostic (1.39e-2)" "prognostic unfavorable (1.83e-6)" "unprognostic (5.43e-2)" "unprognostic (5.50e-2)" "unprognostic (1.66e-1)" "unprognostic (2.13e-1)" "unprognostic (2.10e-1)" "unprognostic (4.34e-3)" "unprognostic (3.33e-2)" "unprognostic (1.40e-1)" "unprognostic (1.69e-1)" "unprognostic (1.46e-2)" 12.4 11.1 8.2 9.8 8.2 50.1 11.2 9.5 9.8 6.6 7.9 9.8 8.2 7.5 8.0 16.1 8.0 8.6 7.8 8.2 8.8 10.5 14.1 8.9 10.5 8.3 8.3 7.2 14.1 10.8 10.6 13.3 8.8 8.6 11.9 8.1 9.7 6.0 8.6 16.0 8.6 9.4 7.9 9.2 10.6 16.9 8.8 8.3 9.1 5.7 10.9 16.4 9.7 8.0 25.2 17.6 18.7 23.9 12.7 14.6 53.6 20.3 16.5 31.5 19.9 23.7 23.3 60.3 32.6 20.4 36.1 20.0 35.6 32.8 29.2 36.3 35.1 42.1 21.3 24.9 27.9 55.5 41.7 15.2 48.1 35.0 50.3 20.6 22.5 45.7 66.5 26.4 25.4 17.6 32.7 32.4 70.2 36.3 37.1 32.3 30.1 39.3 26.1 25.2 48.5 49.7 22.0 28.0 72.8 33.2 15.3 24.2 20.9 26.8 28.3 29.6 67.8 53.2 81.2 50.3 23.6 35.4 43.8 8.8 0.6 0.5 0.6 0.6 0.6 0.5 0.9 0.5 0.5 0.8 1.0 1.0 0.7 0.5 0.4 0.9 1.0 0.4 8.2 8.2 9.5 9.8 8.2 8.8 8.3 8.3 8.8 7.9 8.8 8.0 31.3 0.0 9.2 3.9 21.0 50.6 77.8 6.3 29.6 10.8 28.3 25.9 3.6 10.0 5.5 5.5 6.2 24.3 23.6 7.6 23.5 7.7 3.5 16.2 15.7 22.5 15.6 17.2 3.5 9.2 48.5 14.4 10.2 25.4 7.0 13.0 10.8 12.5 12.7 21.9 3.8 10.2 4.1 9.4 19.1 1.8 4.1 15.3 5.4 3.7 6.3 10.9 4.1 3.0 5.0 15.9 7.1 4.1 25.6 87.8 6.1 16.8 4.9 8.8 6.6 12.5 22.0 19.4 37.4 28.6 49.3 40.6 20.2 14.2 11.7 92.7 ZBED2 MGC10796 ENSG00000177494 "Zinc finger BED-type containing 2" Q9BTP6 3 111592900-111595346 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 47.6;thyroid gland: 71.0" "Cell type enriched" "Detected in some" 5 "Alveolar cells type 1: 44.8" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 64.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "naive B-cell: 2.1" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 4 "CAPAN-2: 54.8;EFO-21: 37.4;HaCaT: 53.1;HBEC3-KT: 119.3;RPTEC TERT1: 77.6" "Not detected" "Not detected" HPA029786 Approved "Nuclear bodies,Mitochondria,Cytosol" No No "Cluster 24: B-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 11: Alveolar cells - Smell perception" "Mitochondria, Cytosol" "Nuclear bodies" "HPA029786: AB_10601028" "unprognostic (7.31e-3)" "unprognostic (1.67e-1)" "unprognostic (1.98e-3)" "unprognostic (1.66e-1)" "unprognostic (2.39e-3)" "unprognostic (3.49e-1)" "unprognostic (7.61e-2)" "unprognostic (1.47e-1)" "unprognostic (2.84e-1)" "prognostic unfavorable (8.83e-4)" "unprognostic (2.59e-1)" "unprognostic (1.47e-6)" "unprognostic (3.81e-2)" "unprognostic (4.34e-1)" "unprognostic (4.69e-2)" "unprognostic (3.29e-2)" 0.2 0.0 0.0 1.7 0.4 0.3 0.2 0.0 0.1 5.4 0.0 0.1 0.1 0.1 0.2 12.8 20.0 0.3 0.1 0.0 0.0 0.2 0.0 10.4 6.9 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.2 0.1 0.0 2.8 0.4 0.0 2.2 0.5 0.0 0.0 0.3 0.5 0.0 0.0 47.6 71.0 0.0 12.9 0.4 9.9 0.0 15.3 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 54.8 0.5 37.4 0.0 0.0 53.1 0.0 119.3 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 10.8 0.0 5.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 77.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.3 1.2 0.2 0.1 0.0 2.1 0.6 0.8 0.0 0.2 0.0 0.0 0.5 0.1 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.8 1.1 0.0 0.6 4.5 0.3 3.1 4.6 0.0 0.0 0.0 0.1 0.0 4.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 8.3 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.1 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.6 3.8 0.0 4.5 0.0 0.1 0.2 ZBTB3 FLJ23392 ENSG00000185670 "Zinc finger and BTB domain containing 3" Q9H5J0 11 62748319-62754184 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 12.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035321, HPA035322" Approved Approved Mitochondria NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 5: NTERA-2 - Transcription" "Cluster 29: Early spermatids - Spermatogenesis" Mitochondria "HPA035321: AB_2674569, HPA035322: AB_10610567" "unprognostic (1.39e-1)" "unprognostic (2.08e-2)" "unprognostic (3.48e-2)" "unprognostic (1.83e-3)" "unprognostic (2.93e-1)" "unprognostic (5.52e-3)" "unprognostic (7.85e-2)" "unprognostic (1.37e-1)" "unprognostic (4.56e-2)" "unprognostic (5.02e-2)" "unprognostic (1.23e-2)" "unprognostic (1.83e-1)" "prognostic favorable (1.65e-5)" "prognostic favorable (9.98e-4)" "unprognostic (3.37e-3)" "unprognostic (4.15e-2)" "unprognostic (2.43e-2)" 1.3 1.4 3.2 2.2 4.9 2.3 2.0 3.5 3.9 1.8 1.4 2.4 2.3 1.6 1.9 1.9 4.3 1.0 3.0 2.9 2.6 1.7 1.8 2.8 2.4 4.2 3.7 2.5 2.5 2.2 1.0 2.0 3.9 1.8 2.1 3.1 3.5 2.2 2.8 5.8 2.2 1.8 2.6 2.1 5.0 2.8 3.6 2.8 2.7 3.2 2.6 1.4 1.2 8.1 2.1 3.2 2.6 3.5 4.9 2.4 2.2 2.3 2.4 2.6 2.3 2.1 2.7 3.4 3.3 2.4 1.9 4.6 2.3 2.5 1.2 3.9 3.9 1.8 6.7 2.6 2.4 2.7 3.7 2.7 2.9 2.0 3.0 3.3 2.2 2.7 3.3 3.5 2.6 4.3 3.4 3.1 7.8 1.6 1.6 2.5 2.0 3.3 2.1 2.7 2.4 2.3 2.3 2.9 1.6 3.7 4.3 2.0 2.0 3.9 1.7 2.8 1.3 3.6 2.8 2.9 3.7 1.6 1.5 1.9 7.2 9.4 4.0 5.6 4.8 4.0 4.1 4.9 5.2 3.3 4.6 3.6 2.3 5.0 4.8 1.5 5.9 6.2 3.2 4.9 3.5 3.9 2.9 2.6 4.2 3.7 3.9 2.6 3.6 8.1 1.4 3.2 2.7 0.7 2.1 0.8 1.6 1.3 2.8 2.7 1.6 1.8 3.3 1.5 1.3 0.0 6.2 4.4 0.9 3.2 7.9 3.2 12.8 1.5 2.4 1.7 0.0 0.4 0.5 1.9 2.4 1.9 2.6 1.6 0.0 2.5 1.1 3.0 2.4 0.0 0.5 3.1 4.1 2.2 0.8 7.5 1.5 1.4 0.0 0.0 2.0 1.7 4.1 0.0 2.2 2.1 3.9 3.0 1.0 1.1 2.8 2.7 1.4 4.5 0.0 0.9 1.8 2.9 3.9 1.0 1.1 2.5 1.5 2.1 1.9 1.1 ZBTB6 "ZID, ZNF482" ENSG00000186130 "Zinc finger and BTB domain containing 6" Q15916 9 122908056-122913323 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 10.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054111, HPA076894" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 38: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 59: Non-specific - Transcription" Nucleoplasm Mitochondria "HPA054111: AB_2682384, HPA076894: AB_2686818" "unprognostic (9.74e-3)" "unprognostic (8.40e-2)" "unprognostic (1.45e-2)" "unprognostic (7.84e-2)" "prognostic favorable (2.06e-5)" "unprognostic (1.81e-1)" "unprognostic (2.39e-3)" "unprognostic (1.13e-1)" "unprognostic (1.06e-1)" "unprognostic (6.11e-2)" "unprognostic (1.33e-1)" "unprognostic (7.20e-2)" "prognostic favorable (5.08e-4)" "unprognostic (4.31e-2)" "unprognostic (1.53e-1)" "unprognostic (2.67e-1)" "unprognostic (1.92e-2)" 4.2 4.4 3.4 7.0 3.9 3.2 6.8 5.2 5.8 5.4 2.8 5.3 5.9 6.3 4.0 4.9 5.0 4.0 5.5 3.4 3.6 4.8 4.2 4.5 9.7 3.5 3.6 7.2 4.5 6.6 2.3 4.5 3.8 4.9 4.8 7.3 4.5 4.7 6.7 5.0 5.8 4.7 4.1 6.7 5.5 5.5 3.5 7.3 7.5 7.0 9.2 5.3 2.6 5.3 5.1 5.9 9.3 8.5 9.6 9.2 9.4 8.4 10.3 8.3 7.3 6.1 6.3 8.1 5.1 7.6 7.4 22.8 9.8 10.3 10.3 11.5 7.8 8.6 11.9 5.7 9.5 11.4 14.9 7.6 15.5 7.6 12.5 10.2 7.7 10.1 9.2 9.7 12.1 9.6 11.6 7.7 11.7 15.0 9.9 6.1 25.6 11.4 8.7 8.3 11.7 15.2 13.0 12.6 8.2 9.8 15.8 7.4 7.9 9.0 7.0 9.2 9.8 17.0 21.7 2.2 10.5 7.7 9.3 10.6 1.5 2.3 1.2 1.7 1.7 1.4 1.7 1.2 1.6 1.0 2.4 2.2 2.0 2.5 2.9 0.9 2.0 1.7 3.4 3.9 5.2 5.8 3.4 3.6 3.5 3.6 3.8 4.1 3.5 5.3 5.3 6.4 3.6 3.6 6.8 2.2 3.1 2.9 3.4 8.0 4.1 2.9 3.5 7.2 6.9 1.8 10.4 2.3 7.2 3.5 0.0 2.7 9.1 4.4 7.6 4.4 3.0 2.1 4.6 2.5 1.3 5.4 4.1 3.7 7.6 5.0 6.1 3.1 2.4 6.7 5.1 3.9 4.1 7.6 4.0 4.4 3.1 4.1 1.8 3.7 4.3 8.8 2.1 6.6 6.8 2.9 2.5 7.9 3.7 4.1 2.9 4.2 5.3 10.6 6.6 5.1 5.2 6.0 5.1 4.9 2.7 1.9 5.8 5.0 3.4 3.2 ZC2HC1C "C14orf140, FAM164C" ENSG00000119703 "Zinc finger C2HC-type containing 1C" Q53FD0 14 75064109-75119502 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 23.9;testis: 55.3" "Group enriched" "Detected in many" 5 "Early spermatids: 165.2;Late spermatids: 195.1;Spermatocytes: 198.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "CAPAN-2: 6.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA050928, HPA065062" Enhanced Approved "Nuclear speckles,Mitochondria" No No "Cluster 22: NK-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" Mitochondria "HPA050928: AB_2681277, HPA065062: AB_2732728" "unprognostic (8.01e-2)" "unprognostic (2.01e-2)" "unprognostic (9.61e-2)" "unprognostic (8.01e-2)" "unprognostic (1.97e-3)" "unprognostic (6.00e-2)" "unprognostic (8.94e-2)" "unprognostic (1.20e-2)" "unprognostic (3.71e-3)" "unprognostic (3.22e-2)" "unprognostic (1.09e-3)" "unprognostic (2.26e-1)" "prognostic favorable (4.63e-13)" "unprognostic (4.69e-3)" "unprognostic (7.37e-2)" "unprognostic (3.12e-1)" "unprognostic (1.81e-1)" 1.1 2.5 2.5 0.6 2.7 0.4 1.7 2.8 2.9 1.8 5.1 2.7 3.1 1.3 23.9 1.3 11.0 1.6 5.2 2.4 2.9 5.5 8.4 2.5 0.2 3.1 3.7 0.6 5.1 6.9 6.1 0.8 2.9 1.3 2.4 2.6 2.9 3.4 4.7 1.6 2.4 1.0 2.8 0.8 1.6 55.3 2.9 2.3 7.0 1.5 0.5 1.4 0.6 3.3 3.8 2.8 0.3 3.3 0.2 0.0 1.8 0.3 1.1 1.4 0.8 4.8 6.9 3.3 2.6 0.4 2.6 1.0 0.0 0.0 1.2 3.9 0.3 0.6 1.0 2.3 2.5 0.0 1.8 0.3 0.4 1.6 0.0 1.7 1.1 0.2 5.8 1.0 0.7 0.6 0.4 0.3 0.7 2.4 1.8 0.0 0.2 0.7 4.3 0.3 5.7 1.3 2.4 2.0 1.5 0.6 2.9 0.9 0.7 0.9 0.9 1.0 0.8 4.0 4.9 1.1 1.4 0.4 0.6 0.3 0.0 0.2 0.6 0.0 0.1 0.4 0.3 0.1 0.1 0.2 0.1 0.1 0.1 1.2 0.1 0.2 0.9 0.1 2.5 2.7 2.8 2.9 2.4 2.9 3.1 3.7 2.9 2.8 2.9 3.3 0.8 6.4 9.7 2.0 0.9 1.8 1.9 1.3 4.6 4.5 7.9 5.1 7.0 2.8 6.6 11.0 10.4 2.3 1.6 2.5 3.9 4.6 165.2 21.0 2.1 2.0 5.3 0.4 2.4 1.4 1.1 2.5 1.1 1.9 1.3 1.1 2.9 4.7 1.7 11.8 2.1 2.3 0.0 1.0 0.7 195.1 3.1 1.0 3.6 1.0 0.9 3.0 8.2 0.5 1.0 1.6 0.6 2.6 0.6 2.8 4.2 7.4 32.5 8.5 6.6 5.2 2.0 198.5 5.5 1.9 0.9 5.1 0.9 2.3 3.9 1.3 ZCCHC24 "C10orf56, FLJ90798, Z3CXXC8" ENSG00000165424 "Zinc finger CCHC-type containing 24" Q8N2G6 10 79382325-79445624 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 148.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 66.0;Hepatic stellate cells: 64.2;Hepatocytes: 59.2;Leydig cells: 68.6;Oligodendrocyte precursor cells: 184.5;Oligodendrocytes: 130.6;Peritubular cells: 65.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 135.0;ASC TERT1: 115.1;BJ hTERT+: 91.6;HSkMC: 120.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038348 Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" Mitochondria Nucleoplasm "HPA038348: AB_10669538" "unprognostic (3.47e-3)" "unprognostic (8.70e-3)" "unprognostic (3.35e-1)" "unprognostic (1.67e-1)" "unprognostic (1.23e-1)" "unprognostic (7.28e-2)" "unprognostic (2.17e-2)" "unprognostic (2.25e-2)" "unprognostic (2.62e-1)" "prognostic unfavorable (3.76e-4)" "unprognostic (4.77e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (5.35e-6)" "unprognostic (1.84e-2)" "unprognostic (5.52e-2)" "unprognostic (2.85e-2)" "unprognostic (2.95e-3)" 40.4 11.9 119.7 13.8 147.7 2.6 32.5 112.0 109.7 42.3 44.8 67.7 6.2 42.8 8.9 14.0 34.1 23.8 35.7 89.4 101.0 8.7 33.1 22.7 7.5 134.9 145.8 26.4 8.4 4.0 9.4 16.1 120.3 32.2 8.9 3.7 12.0 27.2 58.0 13.7 18.2 36.1 119.7 10.9 25.5 8.9 136.8 2.7 18.4 26.5 4.3 43.2 22.9 148.0 3.3 3.1 10.4 9.0 135.0 115.1 2.5 24.6 91.6 14.2 16.5 2.6 0.1 0.1 13.1 49.5 5.0 0.3 1.7 0.6 11.9 6.2 6.5 1.3 7.2 3.1 35.1 3.8 2.0 120.5 1.3 12.8 3.5 42.1 2.9 0.9 4.8 5.3 12.3 1.1 0.1 14.9 2.5 0.6 30.1 0.6 12.3 2.2 1.7 4.0 0.3 12.9 7.7 0.9 31.5 9.7 3.5 7.0 2.0 13.6 12.4 37.4 8.5 9.2 6.5 0.1 27.9 4.9 49.4 0.0 0.6 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.2 0.0 0.9 0.1 0.1 119.7 147.7 112.0 109.7 89.4 101.0 134.9 145.8 120.3 119.7 136.8 148.0 36.2 0.0 2.6 29.0 1.4 7.6 1.4 1.5 1.8 0.1 5.6 5.7 20.2 5.7 1.2 0.0 0.0 0.6 4.5 0.3 0.0 0.8 2.0 2.3 66.0 29.5 0.0 4.4 0.3 0.8 0.9 40.9 5.1 2.6 1.3 4.1 64.2 59.2 10.7 0.0 0.5 0.4 0.0 17.1 14.5 4.8 68.6 7.4 16.0 30.0 5.6 16.7 1.0 184.5 130.6 0.9 0.1 65.5 5.0 2.9 0.0 1.8 1.2 1.1 13.1 38.7 24.0 0.7 1.7 1.4 4.5 1.5 3.6 8.9 0.1 1.3 ZDHHC11 "FLJ13153, ZNF399" ENSG00000188818 "Zinc finger DHHC-type containing 11" Q9H8X9 5 795606-850986 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 19.2;Early spermatids: 17.0;Endometrial ciliated cells: 26.2;Excitatory neurons: 21.4;Inhibitory neurons: 16.4;Oligodendrocytes: 18.3;Respiratory ciliated cells: 25.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "T-47d: 11.5" "HPA057886, HPA069008" Uncertain Approved Mitochondria NA NA "Cluster 43: Testis - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 49: Ciliated cells - Cilium organization" Mitochondria "HPA057886: AB_2683548, HPA069008: AB_2686068" "unprognostic (2.67e-1)" "unprognostic (9.76e-3)" "unprognostic (4.47e-5)" "unprognostic (5.43e-2)" "unprognostic (7.46e-2)" "unprognostic (4.68e-2)" "unprognostic (3.71e-2)" "unprognostic (1.49e-2)" "unprognostic (1.01e-2)" "unprognostic (2.32e-1)" "unprognostic (2.28e-2)" "unprognostic (2.65e-1)" "unprognostic (5.23e-5)" "unprognostic (4.80e-2)" "unprognostic (3.98e-1)" "unprognostic (1.86e-2)" "unprognostic (3.51e-2)" 1.9 0.9 8.0 0.4 9.9 0.5 2.1 8.3 13.0 2.7 8.0 3.5 6.1 1.1 1.8 3.9 6.5 0.9 9.0 7.4 5.1 4.1 5.2 4.7 0.5 7.9 9.9 1.7 2.8 0.6 12.0 0.8 9.0 2.8 0.8 4.3 2.7 0.9 2.0 3.1 2.9 0.5 2.3 3.3 4.4 10.4 7.1 0.7 2.4 2.2 0.7 2.4 2.2 15.0 0.4 7.4 4.1 0.9 1.3 0.3 5.4 0.3 0.1 0.2 0.1 1.0 0.3 3.1 0.8 0.0 0.9 7.1 2.6 0.0 0.0 9.6 4.9 0.3 3.0 3.9 0.4 4.5 0.3 0.4 0.3 0.9 1.0 0.3 0.0 1.2 0.7 1.7 0.2 3.5 0.4 2.5 7.3 0.0 2.8 4.6 2.7 4.3 0.2 1.5 4.2 0.8 0.2 0.1 3.5 8.0 11.5 0.8 0.4 0.2 6.9 3.9 0.1 5.6 8.3 0.9 0.3 9.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 9.9 8.3 13.0 7.4 5.1 7.9 9.9 9.0 2.3 7.1 15.0 0.7 19.2 13.1 8.5 0.0 1.9 0.4 0.6 0.0 3.4 1.6 2.0 7.7 1.5 13.4 0.0 0.0 0.2 0.3 1.2 0.0 0.5 17.0 26.2 3.8 1.5 1.8 0.4 21.4 0.0 0.1 3.6 4.1 4.2 3.8 0.1 1.1 2.7 0.4 6.7 16.4 3.9 0.0 0.0 0.3 9.1 0.6 0.9 0.0 0.0 0.1 0.3 0.0 7.5 18.3 0.2 1.7 0.0 1.4 0.3 6.0 1.3 25.8 2.2 6.6 0.9 1.0 9.5 3.7 0.7 1.6 0.3 1.1 0.1 1.6 0.4 ZDHHC11B ENSG00000206077 "Zinc finger DHHC-type containing 11B" P0C7U3 5 710355-784729 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in many" 6 "brain: 29.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 23.0;Excitatory neurons: 47.2;Inhibitory neurons: 38.3;Oligodendrocyte precursor cells: 26.7;Oligodendrocytes: 70.1;Respiratory ciliated cells: 21.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 2.1;SCLC-21H: 2.4;THP-1: 3.4" "HPA057886, HPA069008" Uncertain Approved Mitochondria NA NA "Cluster 65: Brain - Ion transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA057886: AB_2683548, HPA069008: AB_2686068" "unprognostic (2.81e-1)" "unprognostic (8.38e-3)" "unprognostic (3.79e-2)" "unprognostic (5.11e-3)" "unprognostic (7.18e-2)" "unprognostic (4.02e-3)" "unprognostic (1.19e-1)" "prognostic favorable (3.98e-4)" "unprognostic (4.39e-3)" "unprognostic (1.29e-1)" "unprognostic (1.45e-4)" "unprognostic (6.94e-2)" "unprognostic (1.43e-2)" "unprognostic (9.21e-2)" "unprognostic (1.73e-1)" "unprognostic (5.13e-2)" "unprognostic (2.31e-1)" 0.7 1.2 15.1 0.2 19.6 0.0 0.8 5.9 19.9 0.5 0.0 2.0 2.7 0.4 0.1 1.5 2.0 0.3 4.5 14.6 9.0 0.7 1.2 2.4 0.0 14.2 8.6 0.6 1.8 0.4 4.5 0.2 14.9 0.5 2.3 4.3 1.7 0.5 3.6 2.2 2.4 0.4 3.3 1.2 2.3 0.7 15.5 0.0 1.1 1.6 0.3 1.0 0.6 29.5 0.0 0.8 0.0 0.7 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.6 2.1 0.1 0.0 0.3 0.4 0.0 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 2.4 0.4 0.0 0.0 0.7 0.3 0.0 3.4 0.0 0.0 0.6 0.0 0.0 0.8 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 19.6 5.9 19.9 14.6 9.0 14.2 8.6 14.9 3.3 15.5 29.5 0.2 19.2 23.0 17.0 0.0 2.7 1.0 0.1 2.2 7.0 1.1 0.9 8.9 1.5 5.7 3.7 0.0 0.0 0.4 2.0 0.0 0.8 2.5 11.9 0.7 2.8 3.0 0.0 47.2 0.8 0.1 4.7 4.1 3.6 1.3 0.0 0.7 2.3 1.7 10.1 38.3 6.7 0.0 0.6 1.1 0.4 0.9 0.8 0.0 1.9 0.0 0.6 0.0 26.7 70.1 0.1 1.4 0.0 1.7 0.3 7.7 0.5 21.8 0.3 6.6 1.4 2.4 5.0 2.5 2.3 3.1 0.0 1.5 0.5 2.4 2.6 ZKSCAN1 "KOX18, PHZ-37, ZNF139, ZNF36, ZSCAN33" ENSG00000106261 "Zinc finger with KRAB and SCAN domains 1" P17029 7 100015572-100041689 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 272.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006672 Uncertain Approved "Nucleoplasm,Nuclear bodies,Mitochondria" Yes No "Cluster 18: Basophils - Vesicular transport" "Cluster 15: Liver - Metabolism" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Nuclear bodies" "Nucleoplasm, Mitochondria" "HPA006672: AB_1080707" "unprognostic (2.58e-1)" "unprognostic (1.59e-2)" "unprognostic (3.57e-2)" "unprognostic (4.62e-2)" "unprognostic (1.94e-1)" "unprognostic (2.24e-2)" "unprognostic (1.47e-2)" "unprognostic (4.76e-3)" "unprognostic (3.24e-2)" "unprognostic (1.86e-2)" "unprognostic (6.34e-3)" "unprognostic (8.59e-2)" "unprognostic (1.27e-3)" "unprognostic (7.75e-2)" "unprognostic (1.49e-1)" "unprognostic (1.70e-1)" "unprognostic (9.09e-3)" 12.0 18.4 20.2 11.6 29.1 8.7 22.7 17.2 22.1 16.4 7.4 21.5 18.2 15.5 17.1 18.8 21.7 13.9 10.1 14.4 23.8 13.3 52.8 10.9 11.7 21.3 23.2 19.0 26.1 16.5 10.9 11.0 23.4 23.0 23.5 15.8 25.3 10.8 10.4 32.6 16.9 13.7 13.9 13.5 32.6 11.1 24.1 14.2 11.9 8.8 11.9 12.2 17.4 37.5 17.0 12.3 31.8 34.6 32.0 38.7 12.0 18.6 22.5 10.9 11.0 7.4 15.7 19.1 23.0 20.9 19.1 13.7 18.4 16.1 20.6 18.4 11.3 15.5 15.8 19.3 18.0 29.9 17.7 26.1 25.1 14.7 49.0 29.5 24.4 22.2 36.2 16.3 21.7 22.4 28.4 17.6 12.8 31.6 15.2 16.7 16.2 17.3 18.2 26.4 36.8 44.0 28.9 37.4 32.4 17.8 19.1 19.6 36.8 23.7 23.0 27.9 18.9 18.7 35.3 19.5 16.2 20.8 31.7 16.0 4.0 4.1 5.0 3.1 4.9 3.8 3.9 4.9 5.8 4.8 5.3 3.9 4.2 8.8 9.0 3.9 3.5 3.8 20.2 29.1 17.2 22.1 14.4 23.8 21.3 23.2 23.4 13.9 24.1 37.5 45.3 25.6 55.4 57.5 37.0 15.0 45.7 43.4 71.7 93.9 77.6 38.7 42.8 140.2 61.4 46.0 150.1 41.1 40.1 84.8 15.6 55.9 46.5 89.2 90.9 52.2 220.9 24.6 70.1 43.8 15.3 47.9 103.5 68.0 35.4 120.5 44.6 140.8 19.8 89.2 77.7 99.2 77.3 32.7 18.6 18.4 51.3 31.2 40.9 62.8 45.8 61.2 34.0 102.1 272.5 46.6 81.3 53.4 27.1 93.1 70.4 32.4 153.6 70.1 19.7 87.4 43.9 32.8 16.7 62.9 21.5 65.9 32.3 74.0 114.4 62.0 ZMAT2 "FLJ31121, hSNU23, Snu23" ENSG00000146007 "Zinc finger matrin-type 2" Q96NC0 5 140698680-140706686 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036518 Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 6: Erythroid cells - Oxygen transport" "Nucleoplasm, Mitochondria" "HPA036518: AB_10671960" "unprognostic (4.00e-1)" "unprognostic (2.43e-3)" "prognostic favorable (7.96e-4)" "unprognostic (2.31e-1)" "unprognostic (2.32e-1)" "unprognostic (1.60e-3)" "unprognostic (1.25e-3)" "unprognostic (2.16e-1)" "unprognostic (2.35e-1)" "unprognostic (3.38e-3)" "unprognostic (6.01e-2)" "unprognostic (8.27e-2)" "unprognostic (4.60e-3)" "unprognostic (2.54e-1)" "unprognostic (2.72e-2)" "unprognostic (2.91e-3)" "unprognostic (2.84e-2)" 51.5 53.2 65.8 41.6 76.0 73.0 59.2 61.8 85.6 49.3 63.3 52.1 35.2 49.7 53.0 67.1 51.5 34.0 41.2 70.6 68.7 60.7 57.8 41.7 55.2 65.2 69.0 49.1 38.8 78.1 44.9 47.3 66.0 42.2 56.7 46.9 49.4 46.7 81.7 59.9 45.6 48.2 63.3 55.4 48.8 28.9 68.0 69.2 44.1 79.5 69.4 50.2 51.2 69.8 78.2 128.0 81.5 138.5 128.8 85.8 109.5 79.2 84.9 107.0 114.9 195.5 127.7 87.0 126.2 136.7 121.6 72.9 116.7 158.0 136.4 96.2 99.9 70.6 151.0 138.3 82.1 168.5 89.0 100.0 119.1 111.2 128.0 106.6 90.9 138.1 81.0 93.5 100.6 117.2 135.1 115.4 61.4 54.7 79.5 93.0 96.4 96.9 92.5 110.3 96.8 73.0 112.5 109.8 124.5 115.5 151.6 144.6 77.4 92.5 50.8 48.3 123.4 60.0 130.9 97.5 100.7 114.5 73.7 63.7 37.2 59.9 30.7 29.9 38.7 29.6 33.3 32.3 27.0 27.6 30.6 33.6 96.9 29.3 31.9 28.8 34.8 30.2 65.8 76.0 61.8 85.6 70.6 68.7 65.2 69.0 66.0 63.3 68.0 69.8 44.1 51.3 81.3 9.1 63.8 56.7 76.9 70.8 50.1 30.5 52.4 56.8 87.1 72.9 73.6 69.9 6.2 132.5 66.8 81.0 117.4 80.9 10.8 80.8 69.5 60.0 68.8 170.9 12.8 67.4 126.3 54.5 43.8 70.5 82.8 47.3 51.0 92.7 82.6 16.8 9.7 55.7 44.7 95.8 61.1 11.2 56.5 68.9 58.7 10.3 135.4 82.4 95.8 5.5 9.2 70.9 86.9 57.9 55.3 71.6 68.6 168.0 96.8 22.4 52.6 56.4 58.2 60.1 73.5 68.0 63.2 207.6 71.9 38.0 59.2 87.5 ZNF19 "KOX12, MGC51021" ENSG00000157429 "Zinc finger protein 19" P17023 16 71464555-71565089 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 25.9;Spermatocytes: 15.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" HPA063685 Approved Approved Mitochondria NA NA "Cluster 24: B-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 46: Photoreceptor cells - Phototransduction" Mitochondria "HPA063685: AB_2685090" "unprognostic (5.59e-4)" "unprognostic (1.38e-1)" "unprognostic (1.39e-1)" "unprognostic (2.05e-4)" "unprognostic (6.02e-3)" "unprognostic (4.92e-2)" "unprognostic (3.34e-2)" "unprognostic (6.97e-3)" "unprognostic (2.23e-1)" "unprognostic (4.84e-2)" "unprognostic (8.90e-4)" "unprognostic (1.31e-1)" "unprognostic (3.04e-6)" "unprognostic (3.38e-1)" "unprognostic (1.03e-1)" "unprognostic (2.83e-2)" "unprognostic (4.87e-2)" 3.3 3.2 1.7 2.4 3.1 2.6 3.5 2.5 6.0 2.0 3.1 2.4 3.7 3.9 8.3 4.4 8.3 6.5 4.3 4.3 0.6 3.5 2.3 4.3 3.1 0.4 0.1 4.2 6.2 4.3 5.3 1.8 0.0 3.2 2.1 11.3 3.4 2.0 9.7 6.5 3.1 1.5 0.0 2.7 2.9 16.2 1.6 1.1 8.2 1.7 1.4 1.7 0.6 5.7 1.2 1.0 2.9 2.8 1.3 0.9 2.0 1.9 0.9 1.1 1.2 2.1 3.9 1.7 2.1 0.9 2.0 1.4 1.4 1.7 0.4 1.3 1.3 2.3 2.2 3.2 0.8 2.3 1.9 2.1 1.8 1.5 3.2 2.5 0.5 3.0 1.3 2.1 1.4 1.8 1.6 1.5 1.5 0.7 2.5 1.0 2.5 0.6 1.6 2.2 4.0 3.0 3.3 1.1 2.6 1.9 2.2 1.8 1.0 3.3 1.7 2.1 1.8 1.9 1.9 0.4 2.7 1.3 1.8 2.3 0.9 0.8 1.1 0.8 0.3 2.1 1.2 1.1 0.7 2.4 1.5 1.4 1.7 0.9 1.0 1.3 0.5 0.6 1.7 3.1 2.5 6.0 4.3 0.6 0.4 0.1 0.0 0.0 1.6 5.7 1.4 0.0 3.2 3.9 3.7 0.3 2.0 2.1 1.2 3.8 3.1 1.8 1.2 1.5 2.3 1.8 10.4 1.4 2.3 1.8 5.9 4.4 7.3 6.3 1.3 1.6 1.2 3.6 1.7 1.4 0.8 2.1 0.5 1.2 0.0 5.0 2.2 4.1 1.4 10.1 1.6 2.0 2.0 1.0 1.6 4.4 0.6 0.9 0.0 2.8 1.3 3.5 0.0 2.0 2.1 2.2 1.7 1.9 0.8 1.3 3.6 3.3 10.0 25.9 6.6 2.2 2.0 15.3 7.6 0.8 0.6 0.5 1.8 3.4 1.5 1.0 ZNF200 ENSG00000010539 "Zinc finger protein 200" P98182 16 3222325-3236221 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 17.6" "Cell type enhanced" "Detected in many" "Early spermatids: 51.8;Spermatocytes: 39.0;Spermatogonia: 44.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018981, HPA059310" Uncertain Approved Mitochondria No No "Cluster 2: Granulocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Mitochondria "HPA018981: AB_1859021, HPA059310: AB_2683974" "unprognostic (1.74e-1)" "unprognostic (5.74e-2)" "unprognostic (3.21e-2)" "unprognostic (8.78e-2)" "unprognostic (9.72e-2)" "unprognostic (3.71e-2)" "unprognostic (1.31e-1)" "unprognostic (2.20e-1)" "unprognostic (7.55e-2)" "unprognostic (2.16e-1)" "unprognostic (3.80e-2)" "unprognostic (2.98e-2)" "unprognostic (2.68e-1)" "unprognostic (1.12e-2)" "unprognostic (1.89e-1)" "unprognostic (1.11e-1)" "unprognostic (5.23e-3)" 3.7 3.0 2.2 5.8 2.3 2.4 4.4 3.1 3.3 3.5 2.2 3.4 4.1 3.8 3.7 3.3 4.3 3.5 3.4 2.4 2.5 3.5 3.9 4.0 7.0 2.5 2.3 4.4 2.2 4.7 2.4 6.3 2.3 3.4 3.6 4.0 2.8 3.4 2.1 3.2 3.2 3.9 2.4 6.1 3.3 17.6 2.4 5.2 3.3 3.6 6.6 4.2 2.9 2.4 7.1 7.3 16.1 11.6 5.9 6.1 19.2 9.1 11.2 12.2 11.2 11.2 5.9 13.6 6.8 7.4 7.2 5.3 13.2 9.8 14.6 12.7 12.2 11.3 9.6 9.5 7.8 19.9 26.0 6.2 8.3 9.0 8.1 7.0 10.8 9.7 12.8 10.3 11.1 6.5 14.0 10.8 25.3 8.8 6.9 16.9 22.0 16.0 7.6 4.0 9.1 13.3 8.6 6.5 7.5 11.0 9.3 21.9 7.4 12.4 11.4 4.5 8.0 25.8 27.1 11.9 3.0 12.3 9.8 32.4 5.3 18.4 10.6 6.8 10.3 7.2 9.4 12.5 6.6 6.9 9.6 10.9 22.1 11.6 6.6 4.2 12.1 7.2 2.2 2.3 3.1 3.3 2.4 2.5 2.5 2.3 2.3 2.4 2.4 2.4 10.7 3.2 3.7 4.2 6.4 3.2 4.5 4.2 1.2 5.4 5.2 5.8 3.9 5.7 5.1 3.7 12.5 7.5 7.4 3.3 3.9 5.0 51.8 3.6 3.2 8.1 6.7 9.1 5.2 4.0 6.7 5.0 0.5 3.1 5.1 5.7 10.4 3.8 7.1 0.0 4.1 3.8 4.1 6.6 5.4 22.6 5.6 6.6 7.2 1.9 6.3 6.7 13.4 5.0 3.4 3.6 6.3 3.0 5.7 4.6 3.7 2.8 3.5 8.1 6.6 7.4 4.5 39.0 44.9 4.3 3.1 5.9 8.5 6.1 3.5 4.0 ZNF211 "CH2H2-25, ZNF-25" ENSG00000121417 "Zinc finger protein 211" Q13398 19 57630395-57644041 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA011340, HPA049967" Approved Approved "Mitochondria,Rods & Rings" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 6: Erythroid cells - Oxygen transport" Mitochondria "Rods & Rings" "HPA011340: AB_2668488, HPA049967: AB_2680973" "unprognostic (6.47e-2)" "unprognostic (3.28e-2)" "unprognostic (2.83e-2)" "unprognostic (1.55e-1)" "unprognostic (1.74e-1)" "unprognostic (2.77e-1)" "unprognostic (5.81e-2)" "unprognostic (3.72e-2)" "unprognostic (6.66e-2)" "unprognostic (1.03e-1)" "unprognostic (3.27e-3)" "unprognostic (1.83e-2)" "unprognostic (1.03e-1)" "unprognostic (3.48e-1)" "unprognostic (1.18e-1)" "unprognostic (1.33e-1)" "unprognostic (4.72e-3)" 7.3 11.3 14.1 7.2 13.4 23.7 9.3 14.9 15.9 8.9 19.1 11.2 4.2 8.6 10.1 6.8 10.0 6.2 13.6 13.5 13.5 11.5 6.7 9.1 12.0 12.9 12.6 10.9 6.9 16.7 17.2 10.6 12.5 13.1 8.1 18.5 8.5 11.7 6.3 11.0 11.2 8.2 12.0 17.5 15.2 6.5 13.5 13.5 16.1 7.0 12.7 11.3 7.5 14.4 4.6 3.1 13.5 12.2 7.9 7.5 7.8 6.3 7.9 9.1 5.9 2.5 2.7 4.3 2.6 6.8 5.4 1.0 6.4 9.4 18.9 5.4 15.3 8.6 7.0 5.6 6.5 5.8 8.5 6.8 11.5 6.9 6.2 13.2 6.9 7.8 1.8 5.4 11.5 2.3 12.1 4.5 5.3 5.9 7.0 7.6 10.3 3.8 7.7 17.9 6.1 8.4 7.5 3.5 3.0 14.8 4.1 8.5 3.3 9.1 4.4 3.9 5.3 7.7 10.1 8.9 2.4 4.9 5.3 10.0 5.8 12.4 7.3 5.7 12.4 8.0 9.6 10.8 7.1 10.8 11.6 8.3 7.8 7.5 4.1 1.6 11.6 6.5 14.1 13.4 14.9 15.9 13.5 13.5 12.9 12.6 12.5 12.0 13.5 14.4 5.0 3.2 3.4 10.4 8.2 1.1 1.8 4.4 4.0 4.0 5.0 3.8 4.3 1.5 3.6 1.8 8.4 8.2 7.8 2.1 0.0 4.1 0.8 5.0 4.5 4.8 1.2 12.8 4.1 1.1 5.2 3.0 8.6 2.7 5.7 3.9 4.6 2.0 4.0 0.0 3.9 2.8 6.1 5.7 3.9 1.2 1.2 4.0 1.8 5.6 3.9 4.7 6.2 12.5 7.6 1.3 1.0 2.2 4.1 1.9 5.0 1.4 12.0 7.2 13.1 2.3 4.0 2.4 3.1 1.9 1.7 17.8 8.5 3.1 2.9 3.0 ZNF223 ENSG00000178386 "Zinc finger protein 223" Q9UK11 19 44051367-44067999 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RT4: 23.4" "HPA067823, HPA079175" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 64: Macrophages - Immune response" "Cluster 15: RT4 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" Nucleoplasm Mitochondria "HPA067823: AB_2685906, HPA079175: " "unprognostic (6.15e-2)" "unprognostic (1.06e-1)" "unprognostic (1.27e-1)" "unprognostic (1.63e-1)" "unprognostic (1.02e-2)" "unprognostic (2.42e-1)" "unprognostic (8.36e-2)" "unprognostic (1.29e-2)" "unprognostic (1.86e-3)" "unprognostic (1.04e-1)" "unprognostic (1.20e-2)" "unprognostic (1.85e-1)" "unprognostic (6.32e-2)" "unprognostic (4.33e-1)" "unprognostic (4.95e-2)" "unprognostic (3.67e-1)" "unprognostic (2.58e-4)" 3.2 3.8 2.9 3.5 2.8 2.0 5.5 3.9 3.7 3.6 2.3 4.5 4.0 3.3 5.9 3.0 3.9 3.8 4.9 2.4 3.3 3.9 2.6 3.9 3.6 2.8 2.7 4.0 2.8 4.9 4.1 5.5 3.0 6.5 5.7 4.5 3.6 4.8 2.1 4.9 4.4 3.9 2.5 4.9 4.9 3.2 3.4 2.7 6.3 1.6 4.3 3.9 3.0 3.0 2.8 1.5 5.9 1.4 3.8 4.7 0.1 4.2 4.6 3.7 5.3 2.8 4.6 0.0 3.9 3.3 2.2 2.6 0.0 4.7 3.9 0.1 4.5 5.6 5.0 3.9 2.8 0.3 0.1 4.6 3.7 3.1 3.0 5.2 4.2 0.1 0.2 0.0 4.2 2.2 0.0 2.1 4.4 1.9 2.1 0.0 2.4 1.3 4.5 23.4 3.6 8.5 7.3 0.9 2.9 7.5 4.1 5.2 4.2 3.5 3.3 1.9 1.6 2.7 5.0 0.0 1.5 0.1 3.4 15.0 4.9 7.8 2.4 5.9 3.5 3.2 3.8 1.9 5.4 3.3 7.4 3.2 0.4 6.2 2.7 6.6 3.6 2.4 2.9 2.8 3.9 3.7 2.4 3.3 2.8 2.7 3.0 2.5 3.4 3.0 2.4 0.0 1.1 4.2 1.3 0.0 0.6 0.0 1.2 3.6 1.7 1.4 0.9 2.8 0.0 1.8 2.1 2.1 0.9 2.2 3.9 2.3 3.8 1.4 1.0 1.8 0.0 3.0 6.1 0.5 0.8 1.8 2.0 1.5 0.0 1.8 3.3 0.4 1.7 3.3 5.0 2.8 0.0 2.4 0.0 1.0 1.5 1.3 0.0 1.9 1.7 1.2 3.1 4.5 3.4 1.4 1.5 1.9 0.3 0.6 2.3 1.1 0.7 1.6 0.0 0.7 1.4 1.9 2.1 1.9 0.0 1.0 0.7 1.3 1.7 0.7 ZNF230 FDZF2 ENSG00000159882 "Zinc finger protein 230" Q9UIE0 19 44002957-44013924 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA006172 Approved Mitochondria No No "Cluster 5: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 43: THP-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Mitochondria "HPA006172: AB_2667532" "unprognostic (3.55e-3)" "unprognostic (5.21e-2)" "unprognostic (2.88e-2)" "unprognostic (1.78e-1)" "unprognostic (2.01e-2)" "unprognostic (4.27e-2)" "unprognostic (5.88e-2)" "unprognostic (3.89e-2)" "unprognostic (3.79e-2)" "unprognostic (1.35e-1)" "unprognostic (4.08e-4)" "unprognostic (2.45e-2)" "unprognostic (1.14e-2)" "unprognostic (8.59e-2)" "unprognostic (1.68e-1)" "unprognostic (4.62e-2)" "unprognostic (1.42e-5)" 2.0 2.1 1.1 2.2 1.3 3.2 3.2 2.8 2.0 2.3 1.5 2.0 1.3 2.3 2.1 1.4 2.5 1.6 1.8 1.1 1.4 1.7 2.1 2.4 3.4 1.2 1.3 4.2 1.4 2.7 2.7 2.4 1.4 2.2 2.0 4.6 1.9 2.5 0.8 2.9 2.4 1.8 1.3 3.9 1.9 1.8 1.3 4.0 3.0 1.9 3.9 2.0 1.7 1.8 2.1 1.7 3.4 3.5 2.7 3.3 1.3 2.9 2.9 2.6 4.7 1.0 1.1 1.7 1.9 2.1 1.6 1.7 2.9 2.6 3.9 2.1 3.6 2.9 4.1 1.2 1.5 3.8 2.4 2.5 2.4 2.9 3.0 3.5 1.8 2.0 0.5 0.0 2.7 1.1 4.3 2.7 2.0 1.4 1.6 3.1 4.7 0.8 1.5 2.4 1.9 4.3 4.1 1.4 2.1 2.3 1.2 8.7 2.3 4.1 3.0 1.2 2.2 2.1 2.2 0.3 2.0 2.8 2.6 6.2 3.3 8.7 3.6 4.0 3.8 4.2 4.1 3.7 3.6 4.2 4.5 4.2 11.5 2.9 2.0 2.2 3.7 2.9 1.1 1.3 2.8 2.0 1.1 1.4 1.2 1.3 1.4 1.3 1.3 1.8 4.7 0.0 2.2 1.6 8.3 2.8 2.6 3.0 4.6 8.5 3.3 3.9 6.0 10.0 3.5 3.7 16.7 4.0 9.9 2.7 3.9 3.0 2.7 2.9 3.3 4.2 1.2 2.1 4.6 2.4 3.2 4.4 2.6 1.7 1.3 4.8 3.9 2.7 3.2 8.4 3.8 2.4 10.2 4.4 3.3 1.7 6.5 3.6 3.6 3.7 7.9 5.4 7.2 2.5 4.0 1.2 0.8 4.5 1.4 2.0 4.1 1.6 2.9 9.6 6.6 3.9 4.3 13.7 7.9 2.8 2.7 3.1 6.7 3.7 3.2 2.0 ZNF26 "FLJ20755, KOX20" ENSG00000198393 "Zinc finger protein 26" P17031 12 132986365-133032952 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA018329, HPA042406" Uncertain Approved "Nuclear bodies,Mitochondria" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 21: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Mitochondria "Nuclear bodies" "HPA018329: AB_1859157, HPA042406: AB_2677982" "unprognostic (7.31e-3)" "unprognostic (7.60e-3)" "unprognostic (7.26e-4)" "unprognostic (5.52e-2)" "unprognostic (1.15e-1)" "unprognostic (2.09e-2)" "unprognostic (1.52e-3)" "unprognostic (3.00e-2)" "unprognostic (9.56e-3)" "unprognostic (2.09e-1)" "unprognostic (1.11e-1)" "unprognostic (3.67e-3)" "unprognostic (2.66e-12)" "unprognostic (8.24e-2)" "unprognostic (7.20e-2)" "unprognostic (1.94e-3)" "unprognostic (7.64e-4)" 0.8 0.7 1.2 0.9 1.2 1.6 0.8 1.9 1.7 1.0 2.2 0.7 0.8 0.9 1.5 0.6 1.2 0.5 0.6 1.4 0.9 0.8 0.6 1.0 0.9 1.2 0.9 0.9 0.8 0.4 0.7 0.5 0.9 0.7 0.6 1.4 0.8 0.5 1.1 1.4 0.8 0.6 0.4 0.9 0.8 1.1 1.4 0.6 0.8 0.2 0.8 0.7 0.8 2.0 1.3 0.3 1.0 2.0 0.4 0.5 3.4 0.9 0.7 0.9 0.5 0.4 1.0 0.9 1.8 0.8 0.6 1.4 0.4 0.4 0.5 1.1 3.1 2.0 1.2 0.4 0.2 2.7 3.2 0.8 0.7 0.6 1.3 0.8 0.4 1.4 1.3 0.3 0.6 1.4 2.5 1.7 2.2 0.4 2.4 3.0 2.6 2.7 0.3 2.5 2.6 4.2 0.8 1.3 1.1 0.5 2.9 2.4 2.4 1.5 1.1 0.7 1.2 0.7 0.1 3.5 0.9 1.6 1.8 5.9 1.2 3.2 4.0 1.4 4.0 2.1 3.4 2.9 1.8 3.8 4.3 3.8 0.9 3.4 1.3 1.5 3.3 2.8 1.2 1.2 1.9 1.7 1.4 0.9 1.2 0.9 0.9 0.4 1.4 2.0 10.7 22.4 16.0 6.5 15.7 0.0 9.0 0.1 7.4 26.6 9.1 6.7 5.2 11.5 8.2 5.5 25.0 6.4 18.9 3.3 3.9 7.5 1.1 8.8 9.5 10.1 8.4 3.8 11.6 5.7 4.2 8.2 9.2 8.4 9.5 20.3 11.4 5.6 5.3 26.9 8.8 7.0 0.0 6.6 0.0 1.5 8.1 7.5 0.0 11.2 6.5 5.6 17.5 9.5 10.3 8.4 4.9 6.0 10.7 8.1 5.9 2.8 3.0 23.2 0.0 19.1 7.4 12.1 10.9 5.3 0.0 4.8 15.8 14.0 7.2 7.8 ZNF428 "C19orf37, MGC51082, Zfp428" ENSG00000131116 "Zinc finger protein 428" Q96B54 19 43607224-43619629 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042596, HPA048072" Uncertain Approved Nucleoli,Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 14: REH - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoli "HPA042596: AB_2678070, HPA048072: AB_2680249" "unprognostic (2.45e-3)" "unprognostic (5.51e-2)" "unprognostic (6.68e-3)" "unprognostic (6.31e-2)" "unprognostic (1.60e-1)" "unprognostic (1.12e-1)" "unprognostic (3.22e-2)" "unprognostic (2.32e-2)" "unprognostic (2.53e-1)" "unprognostic (6.67e-2)" "prognostic favorable (3.60e-5)" "unprognostic (3.85e-1)" "unprognostic (5.59e-2)" "unprognostic (1.85e-1)" "unprognostic (2.30e-2)" "unprognostic (4.00e-1)" "unprognostic (2.74e-2)" 26.4 43.4 47.5 17.3 45.6 24.0 26.7 39.3 59.8 38.5 28.9 48.8 17.3 43.4 8.9 22.3 34.7 10.7 45.7 46.9 44.9 44.4 39.2 25.2 17.6 44.7 43.9 43.3 30.7 18.1 55.2 13.5 39.0 41.7 6.3 15.6 28.2 14.0 44.1 18.8 25.0 10.7 40.3 30.9 30.1 57.1 52.2 22.0 37.5 14.3 10.0 34.1 26.7 44.6 38.2 33.8 53.2 79.6 20.8 15.5 21.6 28.6 15.6 23.0 24.5 19.8 25.6 66.3 62.7 26.1 13.8 9.4 21.7 6.1 7.8 54.1 87.2 73.4 34.1 34.7 39.0 57.3 55.8 27.8 12.7 19.9 10.3 23.3 32.5 48.3 76.9 40.1 24.6 42.3 140.0 97.9 30.8 17.9 22.8 135.6 23.3 49.1 27.3 25.4 90.2 102.0 44.2 25.5 66.6 14.2 15.3 79.6 55.2 24.1 66.7 22.7 44.5 43.2 56.8 117.1 34.2 56.9 53.4 1.4 2.1 9.3 6.2 1.4 3.1 4.8 5.5 6.1 2.5 6.2 5.9 2.7 0.8 2.6 2.6 5.6 3.9 1.0 47.5 45.6 39.3 59.8 46.9 44.9 44.7 43.9 39.0 40.3 52.2 44.6 67.8 0.0 3.9 26.1 44.5 32.1 80.3 173.5 55.8 101.7 68.6 74.7 19.7 61.5 76.4 66.2 14.6 142.1 78.8 43.1 148.7 89.1 153.3 81.7 79.1 69.3 162.2 66.0 17.6 79.6 46.7 79.3 38.7 59.4 36.3 214.9 76.4 51.4 104.4 57.2 19.7 62.3 156.6 38.6 60.8 63.5 88.9 42.3 113.8 14.0 45.4 191.7 99.9 18.1 26.7 74.5 52.0 90.7 45.5 41.0 30.0 216.8 48.1 72.5 72.3 59.0 102.9 29.6 173.1 44.2 25.9 55.1 71.3 174.1 52.8 53.7 ZNF445 "ZKSCAN15, ZNF168, ZSCAN47" ENSG00000185219 "Zinc finger protein 445" P59923 3 44431705-44477670 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006678 Uncertain Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 72: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Mitochondria, Cytosol" "HPA006678: AB_10603329" "unprognostic (7.72e-2)" "unprognostic (2.55e-1)" "unprognostic (1.12e-2)" "unprognostic (1.42e-1)" "unprognostic (7.14e-2)" "unprognostic (1.67e-2)" "unprognostic (1.79e-2)" "unprognostic (2.72e-2)" "unprognostic (1.60e-2)" "unprognostic (1.62e-1)" "unprognostic (1.03e-2)" "unprognostic (4.55e-2)" "unprognostic (3.11e-3)" "unprognostic (1.76e-1)" "unprognostic (2.48e-1)" "unprognostic (4.40e-3)" "unprognostic (1.05e-1)" 4.2 3.0 2.3 1.8 2.5 1.3 3.9 4.3 2.4 6.0 1.1 4.7 1.4 5.1 2.0 2.7 5.0 1.6 3.6 2.4 2.4 3.3 4.9 4.1 1.9 2.1 2.1 7.0 4.4 2.8 5.0 2.0 2.2 4.4 1.7 4.2 3.6 2.1 4.4 3.7 3.5 2.2 1.7 3.9 3.9 3.1 2.2 3.3 3.8 2.7 2.1 4.1 4.4 2.9 1.9 2.1 6.4 5.1 3.5 3.6 2.9 2.5 2.1 3.7 3.7 3.2 1.6 3.3 1.5 2.6 2.3 1.5 4.4 1.7 4.5 3.6 1.6 6.1 4.7 3.2 2.2 7.8 4.9 2.5 2.1 4.2 2.6 3.1 2.6 4.6 4.8 2.4 3.0 1.2 7.5 5.2 4.4 1.2 1.9 3.3 4.0 1.6 2.0 3.8 3.2 3.9 3.9 2.0 1.0 4.7 3.7 3.4 3.2 5.2 4.6 3.2 3.2 1.9 1.5 2.7 1.9 3.8 3.2 1.0 0.3 0.6 0.3 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.3 0.2 1.0 0.5 0.8 0.3 0.1 0.1 2.3 2.5 4.3 2.4 2.4 2.4 2.1 2.1 2.2 1.7 2.2 2.9 11.7 12.8 17.4 19.2 8.4 4.1 4.4 2.9 9.6 36.0 4.8 4.4 11.1 5.7 7.6 11.0 37.5 4.1 15.7 3.8 1.9 5.8 2.5 6.3 14.1 9.7 7.2 10.3 21.7 8.4 1.7 9.0 7.1 6.8 11.4 26.6 13.2 10.1 5.7 28.6 24.3 6.3 2.0 16.4 4.7 2.2 9.3 10.5 0.0 9.4 11.6 10.1 22.6 11.6 19.5 4.9 6.0 9.8 9.5 5.6 4.3 2.8 9.6 28.4 13.1 14.5 10.6 6.7 6.9 5.6 2.6 1.4 9.8 9.3 7.2 3.8 ZNF467 "EZI, Zfp467" ENSG00000181444 "Zinc finger protein 467" Q7Z7K2 7 149764182-149773588 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 60.2;Distal tubular cells: 39.2;Hepatic stellate cells: 40.7;Kupffer cells: 56.8;monocytes: 37.1;Muller glia cells: 75.3" "Cancer enhanced" "Detected in all" "ovarian cancer: 22.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 48.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 48.6" "Cell line enhanced" "Detected in many" "AN3-CA: 28.8;EFO-21: 13.5;HMC-1: 15.9;MCF7: 12.9;SK-BR-3: 12.7;T-47d: 15.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042907 Uncertain Approved Mitochondria NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 5: Muller glia cells - Visual perception" Mitochondria "HPA042907: AB_10966965" "unprognostic (3.01e-1)" "unprognostic (2.41e-1)" "unprognostic (6.40e-4)" "unprognostic (5.99e-2)" "unprognostic (2.91e-1)" "unprognostic (1.33e-1)" "unprognostic (1.20e-1)" "unprognostic (1.46e-1)" "unprognostic (6.88e-2)" "unprognostic (5.14e-2)" "prognostic favorable (4.56e-4)" "unprognostic (2.12e-1)" "unprognostic (8.15e-2)" "unprognostic (3.19e-1)" "unprognostic (1.51e-1)" "unprognostic (2.53e-2)" "unprognostic (2.25e-2)" 13.2 9.5 7.1 3.8 12.8 10.7 8.9 5.7 7.5 10.1 4.8 10.6 1.0 10.5 1.5 5.5 13.8 3.1 10.7 6.9 6.7 25.5 14.6 16.3 3.7 8.5 8.5 8.5 14.8 5.6 14.5 2.0 7.5 7.4 1.4 11.1 9.3 3.8 1.6 9.3 7.9 2.7 7.0 27.6 16.1 1.5 8.0 4.2 16.1 3.0 2.3 7.0 6.9 5.5 0.0 3.4 4.2 28.8 0.1 0.0 0.1 0.1 0.0 0.4 0.1 1.0 8.6 0.2 13.5 0.2 0.1 0.3 2.2 0.1 0.2 0.1 0.4 1.6 0.0 0.0 8.7 0.0 15.9 5.8 1.2 0.0 0.1 10.9 3.0 0.6 2.5 0.7 0.0 12.9 0.5 1.4 0.4 1.3 8.3 2.3 0.1 10.7 2.1 0.0 1.4 1.2 0.0 12.7 0.0 1.4 15.6 1.3 6.3 0.2 4.4 0.0 0.0 0.6 0.0 0.2 0.2 4.9 0.1 0.0 8.9 4.4 0.3 3.7 0.2 0.0 0.4 0.4 5.8 0.0 0.6 0.2 48.6 0.2 1.2 2.9 0.0 2.4 7.1 12.8 5.7 7.5 6.9 6.7 8.5 8.5 7.5 7.0 8.0 5.5 10.3 0.0 0.5 4.2 1.2 3.6 0.6 1.3 0.6 60.2 13.3 6.9 2.0 2.8 4.1 0.0 2.1 0.4 10.6 0.0 39.2 7.7 0.4 2.6 5.0 23.7 3.0 8.0 0.8 2.9 0.2 3.9 2.6 2.1 0.0 0.3 40.7 7.7 22.3 6.7 2.9 0.0 8.2 56.8 19.4 0.3 1.5 23.0 1.8 2.8 37.1 75.3 6.2 0.5 0.2 1.8 0.0 1.9 1.1 0.8 0.0 8.5 1.7 6.5 0.0 0.6 2.8 1.0 2.9 0.7 7.4 0.4 2.8 0.3 0.0 0.5 ZNF48 "DKFZp762K013, FLJ31751, MGC43952, ZNF553" ENSG00000180035 "Zinc finger protein 48" Q96MX3 16 30378106-30400108 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "REH: 47.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023806 Uncertain Approved Mitochondria No No "Cluster 48: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 14: REH - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA023806: AB_1859335" "unprognostic (5.35e-2)" "unprognostic (7.91e-3)" "unprognostic (2.41e-3)" "unprognostic (2.06e-1)" "unprognostic (5.20e-2)" "unprognostic (1.66e-2)" "unprognostic (2.77e-3)" "unprognostic (4.25e-2)" "unprognostic (6.06e-2)" "unprognostic (2.19e-1)" "prognostic favorable (1.20e-6)" "unprognostic (5.36e-2)" "prognostic favorable (7.50e-5)" "unprognostic (6.35e-2)" "unprognostic (1.19e-1)" "unprognostic (1.04e-1)" "unprognostic (2.45e-3)" 2.9 5.1 7.1 3.4 7.3 2.0 3.2 7.9 8.2 4.5 3.9 8.0 3.7 7.2 2.5 2.8 5.7 2.5 4.4 7.5 6.6 4.2 4.2 3.5 4.5 5.7 6.0 3.2 5.6 6.4 5.1 2.0 5.8 4.6 2.4 3.8 4.2 4.4 5.3 4.2 4.1 4.5 5.3 4.2 4.9 2.4 6.7 8.1 3.5 3.7 3.0 5.5 2.8 7.1 7.7 13.4 32.0 25.2 4.3 3.0 9.8 5.7 9.7 12.1 11.2 6.7 10.0 16.2 10.7 5.3 3.4 6.6 15.7 8.9 6.8 12.0 20.2 7.2 6.9 10.2 5.9 9.6 9.1 2.6 11.0 10.0 6.6 11.4 10.9 14.3 12.6 7.2 5.3 28.1 20.8 11.9 26.4 6.0 5.4 47.7 7.4 20.0 7.4 6.6 25.1 31.6 2.5 16.7 2.5 8.4 11.2 8.9 5.1 7.0 8.1 6.3 6.5 8.6 10.9 14.8 4.0 5.8 1.7 0.0 0.0 0.4 0.9 0.0 0.6 0.3 0.4 0.5 0.1 0.3 0.5 0.6 0.0 0.9 0.0 0.4 0.5 0.1 7.1 7.3 7.9 8.2 7.5 6.6 5.7 6.0 5.8 5.3 6.7 7.1 4.0 3.2 2.2 4.6 6.1 3.1 2.5 1.7 4.0 11.7 4.8 5.1 5.4 14.3 3.9 3.7 8.4 3.7 6.7 4.8 1.9 10.4 0.2 3.7 2.8 5.4 9.6 5.2 4.9 7.4 2.2 2.8 1.5 3.7 17.2 7.5 4.2 3.1 2.7 16.8 5.5 4.0 2.0 1.6 2.6 0.3 2.8 1.7 1.8 2.8 6.9 6.6 3.1 1.0 4.0 7.2 5.4 6.8 2.0 4.3 3.5 4.1 1.0 7.3 0.0 3.0 5.5 3.5 3.3 1.8 5.3 0.3 5.0 3.7 6.1 1.7 ZNF596 ENSG00000172748 "Zinc finger protein 596" Q8TC21 8 232137-264703 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 60.1;Late spermatids: 20.4;Oligodendrocytes: 20.7;Spermatocytes: 63.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AN3-CA: 11.4" "Low region specificity" "Detected in all" HPA055463 Uncertain Approved Nucleoli,Mitochondria NA NA "Cluster 42: Non-specific - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoli, Mitochondria" "HPA055463: AB_2682821" "unprognostic (3.30e-1)" "unprognostic (1.47e-1)" "unprognostic (3.01e-2)" "unprognostic (2.41e-1)" "unprognostic (2.90e-1)" "unprognostic (9.07e-3)" "unprognostic (9.68e-3)" "unprognostic (2.10e-3)" "unprognostic (1.74e-1)" "unprognostic (4.84e-1)" "unprognostic (1.70e-5)" "unprognostic (6.37e-2)" "unprognostic (1.20e-1)" "unprognostic (3.10e-2)" "unprognostic (2.39e-1)" "unprognostic (3.51e-1)" "unprognostic (4.53e-1)" 2.6 3.5 4.2 2.0 4.5 1.8 5.2 8.3 5.0 3.8 4.6 2.7 2.7 7.1 7.0 2.3 4.1 2.1 3.4 4.0 5.5 4.2 3.0 3.1 3.8 4.4 4.1 5.0 3.4 4.9 4.6 3.6 4.3 3.9 3.2 18.7 2.3 4.0 2.9 4.5 2.6 3.2 3.2 5.0 3.7 15.5 5.1 3.4 5.7 1.8 2.8 2.7 2.5 6.8 1.6 1.1 4.5 11.4 2.1 2.3 3.6 3.6 1.5 1.3 2.4 1.1 2.0 1.6 1.3 2.7 1.9 3.3 1.2 2.6 1.7 1.2 1.9 3.3 3.3 1.3 2.4 1.4 1.8 4.8 0.4 1.5 2.4 2.2 1.0 5.7 2.4 5.4 7.8 5.6 4.0 1.8 2.4 3.0 1.1 1.6 1.0 2.7 4.4 2.7 2.7 6.7 2.3 1.2 1.8 2.3 3.6 4.1 2.6 3.3 0.9 0.3 1.8 1.7 5.1 2.2 4.1 1.4 2.4 4.6 1.5 2.3 2.4 1.2 3.1 3.2 2.5 2.2 1.7 3.6 2.9 3.4 1.4 1.5 2.9 2.3 2.9 1.3 4.2 4.5 8.3 5.0 4.0 5.5 4.4 4.1 4.3 3.2 5.1 6.8 2.3 3.2 2.7 10.1 2.2 0.4 0.7 2.6 2.2 8.3 1.3 1.8 2.9 1.5 2.4 1.8 2.1 2.1 0.8 1.6 3.9 2.1 60.1 1.5 2.7 2.5 0.0 1.7 14.1 1.7 1.4 2.1 5.1 1.3 5.1 2.9 2.2 0.9 1.1 11.8 15.7 1.5 4.1 0.8 0.3 20.4 4.1 0.9 0.0 9.4 0.5 5.4 1.0 15.6 20.7 1.3 0.5 1.2 2.9 0.7 1.6 1.9 3.8 9.0 0.0 2.6 1.8 63.7 4.5 3.1 0.4 1.5 1.8 2.9 1.5 0.5 ZNF608 "DKFZp434M098, KIAA1281, NY-REN-36" ENSG00000168916 "Zinc finger protein 608" Q9ULD9 5 124636913-124748807 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Astrocytes: 105.4;Inhibitory neurons: 141.2;Oligodendrocyte precursor cells: 219.2;Oligodendrocytes: 209.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.5;naive B-cell: 1.6" "Group enriched" "Detected in many" 4 "B-cells: 1.6;granulocytes: 2.5" "Cell line enhanced" "Detected in many" "AF22: 61.0;AN3-CA: 39.2;REH: 110.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005545, HPA076984" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 10: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Mitochondria "HPA005545: AB_1080742, HPA076984: " "unprognostic (3.82e-2)" "unprognostic (2.50e-2)" "unprognostic (1.92e-1)" "prognostic unfavorable (5.47e-4)" "unprognostic (3.75e-1)" "unprognostic (2.26e-1)" "unprognostic (3.04e-2)" "unprognostic (5.02e-2)" "unprognostic (7.52e-2)" "unprognostic (5.24e-2)" "unprognostic (3.67e-1)" "unprognostic (2.69e-2)" "prognostic unfavorable (1.28e-5)" "unprognostic (6.36e-2)" "unprognostic (2.80e-1)" "unprognostic (3.02e-1)" "unprognostic (9.56e-2)" 6.1 9.9 10.4 4.2 14.0 1.4 6.7 12.1 10.4 7.4 4.1 5.6 11.1 4.8 2.7 3.5 9.1 6.9 9.0 11.7 12.8 5.3 2.7 10.7 8.0 14.7 12.4 6.3 8.4 3.7 4.4 3.1 12.4 5.6 7.2 23.6 5.7 4.5 6.4 3.3 6.6 4.2 9.2 2.8 6.7 9.4 12.4 4.8 9.2 3.2 8.0 3.1 4.4 17.1 0.2 1.1 61.0 39.2 8.9 14.5 0.0 0.0 1.6 0.3 3.6 6.6 18.6 20.8 20.2 0.0 9.8 0.8 4.2 3.9 0.3 0.0 9.9 0.0 0.1 0.3 13.7 0.0 1.9 14.6 11.0 1.9 1.7 9.1 13.2 0.1 2.0 0.4 3.3 0.1 0.0 0.0 25.9 0.5 0.8 110.6 5.4 0.1 8.7 0.9 9.2 32.0 0.0 0.7 14.1 34.5 3.5 1.8 3.5 12.3 22.9 0.3 3.9 9.7 10.2 36.9 3.1 0.6 17.7 2.5 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.6 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 10.4 14.0 12.1 10.4 11.7 12.8 14.7 12.4 12.4 9.2 12.4 17.1 25.2 32.1 35.3 105.4 7.4 1.3 10.4 5.5 31.3 35.8 8.6 7.7 20.1 18.6 36.2 14.7 39.6 0.8 1.5 13.0 3.9 16.7 16.9 30.6 3.0 23.4 40.0 1.3 17.0 8.7 3.8 9.9 11.7 16.8 0.0 7.3 11.4 2.0 0.8 42.1 141.2 6.1 4.1 0.3 2.2 8.8 2.1 1.3 7.2 28.1 2.1 31.2 0.0 219.2 209.9 6.2 7.3 1.5 3.7 3.5 8.1 8.4 13.2 36.7 0.0 13.2 7.7 19.2 7.2 11.8 0.9 0.4 1.5 19.1 9.8 2.5 ZNF615 FLJ33710 ENSG00000197619 "Zinc finger protein 615" Q8N8J6 19 51991332-52008230 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in all" 4 "prostate cancer: 11.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA052422 Uncertain Approved Nucleoli,Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 89: Fibroblasts - ECM organization" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 43: Cardiomyocytes - Nuclear processes" Mitochondria Nucleoli "HPA052422: AB_2681825" "unprognostic (2.20e-1)" "unprognostic (4.66e-2)" "unprognostic (4.56e-1)" "unprognostic (2.64e-1)" "unprognostic (4.08e-3)" "unprognostic (7.28e-2)" "unprognostic (5.23e-2)" "unprognostic (3.68e-1)" "unprognostic (4.44e-3)" "unprognostic (2.44e-2)" "unprognostic (4.41e-2)" "unprognostic (4.80e-2)" "unprognostic (1.77e-1)" "unprognostic (8.16e-3)" "unprognostic (3.03e-1)" "unprognostic (1.82e-1)" "prognostic favorable (2.98e-4)" 5.2 3.7 4.1 2.9 6.5 5.7 6.6 9.4 5.6 4.9 3.4 4.8 3.5 7.8 4.7 4.2 6.4 5.0 5.9 4.5 6.0 6.0 3.9 5.1 4.4 3.7 4.6 10.2 3.8 10.1 4.6 5.6 3.7 17.5 3.6 9.8 5.5 6.3 3.7 4.7 3.1 6.5 1.8 5.3 4.1 3.7 4.6 4.7 7.6 6.8 4.3 4.2 3.5 8.6 1.5 6.2 5.8 12.4 11.2 8.1 4.7 4.5 6.9 6.4 5.7 1.2 1.7 2.2 2.4 5.0 3.9 1.5 4.7 3.1 5.2 0.3 10.0 7.5 5.6 4.3 8.6 0.0 4.1 6.8 3.7 10.2 10.2 10.6 3.0 2.7 0.0 0.0 4.3 0.5 0.0 3.8 6.1 0.2 9.6 4.7 10.2 4.0 3.9 10.3 5.4 4.7 5.4 4.7 3.2 6.3 7.1 3.4 5.9 5.4 6.2 3.3 3.3 4.3 12.3 2.8 3.0 0.0 8.7 5.8 2.2 4.2 2.5 3.2 5.3 2.8 4.5 3.6 3.3 2.9 4.3 3.1 2.5 8.2 2.0 2.0 4.2 2.9 4.1 6.5 9.4 5.6 4.5 6.0 3.7 4.6 3.7 1.8 4.6 8.6 5.1 6.4 7.2 7.5 4.5 2.8 2.1 1.0 1.8 6.4 4.4 3.4 6.9 5.7 1.4 3.7 6.2 4.1 5.9 2.4 3.9 2.2 2.6 2.3 4.4 3.5 9.0 2.1 10.2 1.2 2.9 5.3 2.0 2.4 0.0 6.2 4.2 2.1 3.0 3.3 7.8 2.7 2.0 3.5 3.6 1.0 2.5 4.1 7.2 5.6 3.8 3.2 7.2 8.0 12.0 1.2 3.9 4.1 3.4 4.3 2.2 3.1 3.1 7.0 6.6 5.2 6.7 3.8 2.2 2.6 4.0 5.1 3.9 2.8 2.8 2.0 ZNF625 ENSG00000257591 "Zinc finger protein 625" Q96I27 19 12142090-12156734 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 10.4;Rod photoreceptor cells: 9.5" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" HPA074014 Approved Nucleoplasm,Mitochondria NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 77: Retina - Visual perception" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 9: Photoreceptor cells - Phototransduction" Mitochondria Nucleoplasm "HPA074014: AB_2686652" "unprognostic (7.88e-3)" "unprognostic (6.74e-2)" "unprognostic (9.56e-2)" "unprognostic (8.75e-2)" "unprognostic (7.21e-3)" "unprognostic (6.11e-3)" "unprognostic (4.72e-2)" "unprognostic (3.31e-2)" "unprognostic (6.23e-2)" "unprognostic (2.73e-1)" "unprognostic (5.49e-2)" "unprognostic (3.70e-2)" "unprognostic (8.29e-2)" "unprognostic (4.41e-2)" "unprognostic (1.50e-1)" "unprognostic (6.98e-2)" "unprognostic (1.62e-1)" 1.2 2.2 2.2 0.8 2.1 1.2 2.4 5.0 6.3 2.2 1.8 2.1 0.8 2.2 2.9 1.3 2.0 0.9 1.9 2.1 3.0 4.0 1.0 1.4 1.2 2.4 2.4 2.1 1.8 1.4 3.5 1.7 2.4 2.8 0.8 8.8 1.8 1.5 0.5 2.1 1.4 1.6 2.4 2.4 1.4 1.6 3.2 0.9 2.8 0.8 1.1 2.1 1.6 2.6 0.7 0.0 5.5 8.7 2.2 1.5 0.9 2.2 2.8 3.2 3.6 0.1 0.1 0.0 4.1 1.6 2.3 0.4 0.0 2.9 2.9 0.0 1.6 2.7 0.0 2.6 0.9 0.1 3.5 1.1 1.2 3.1 1.1 2.3 2.7 0.2 0.0 0.0 4.9 1.9 0.0 1.2 6.6 0.0 1.8 0.2 4.5 0.0 2.7 7.5 3.5 2.4 0.0 0.1 2.0 6.4 3.6 0.2 1.6 7.3 3.5 5.9 3.1 6.1 5.1 0.0 2.0 0.0 2.7 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.5 0.0 0.0 0.4 0.1 2.2 2.1 5.0 6.3 2.1 3.0 2.4 2.4 2.4 2.4 3.2 2.6 2.1 3.2 1.5 0.0 0.5 0.4 0.5 1.0 1.2 5.0 2.0 2.2 0.1 2.8 0.4 1.8 10.4 4.1 0.5 0.5 3.9 3.4 0.1 1.9 3.5 2.5 1.2 0.0 0.0 3.1 3.9 1.3 0.0 1.5 0.0 4.9 6.4 0.8 1.5 5.0 0.0 0.6 2.0 4.1 2.0 1.3 0.6 0.5 0.0 0.0 1.7 5.1 7.2 0.0 0.0 3.6 1.9 1.5 1.6 0.7 0.3 2.7 2.5 9.5 0.0 1.8 1.7 2.9 6.6 0.3 0.9 1.2 0.4 2.0 1.0 0.3 ZNF678 MGC42493 ENSG00000181450 "Zinc finger protein 678" Q5SXM1 1 227563543-227677443 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 38.2;Oligodendrocytes: 44.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" HPA028507 Uncertain Approved Nucleoli,Mitochondria,Cytosol Yes No "Cluster 41: Basophils - Cellular respiration" "Cluster 34: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoli, Mitochondria, Cytosol" "HPA028507: AB_10603567" "unprognostic (1.76e-2)" "unprognostic (3.01e-2)" "unprognostic (1.68e-1)" "unprognostic (1.39e-1)" "unprognostic (1.20e-2)" "unprognostic (4.42e-3)" "unprognostic (3.92e-2)" "unprognostic (4.64e-2)" "unprognostic (1.59e-2)" "unprognostic (2.19e-2)" "unprognostic (2.50e-1)" "unprognostic (1.64e-1)" "unprognostic (3.54e-6)" "unprognostic (1.39e-1)" "unprognostic (4.18e-1)" "unprognostic (1.10e-1)" "unprognostic (4.88e-4)" 2.5 3.1 2.2 3.0 3.3 3.4 3.7 3.6 2.8 3.6 1.1 2.9 2.3 3.8 2.4 2.1 3.1 3.1 1.9 2.3 4.3 2.6 2.2 3.2 4.4 3.1 2.8 4.0 3.3 2.3 1.5 4.2 2.8 4.0 4.1 5.7 2.7 2.4 1.5 1.4 2.1 2.4 2.3 3.6 3.3 3.9 3.4 4.4 5.4 2.7 4.0 2.1 2.3 5.6 2.5 4.0 13.6 15.5 1.6 3.7 8.3 3.3 3.2 4.8 4.9 3.3 2.9 9.7 8.3 1.5 2.5 4.6 8.3 2.2 7.6 4.2 15.8 4.5 2.9 2.0 3.0 8.0 12.0 3.3 3.8 2.8 6.0 3.5 4.5 10.9 12.4 15.1 5.2 2.0 11.3 2.8 12.1 3.6 6.3 8.4 8.9 3.9 3.4 7.7 5.8 11.2 4.8 5.6 2.3 6.6 7.9 9.2 3.3 5.9 5.5 5.2 6.6 4.8 11.8 10.5 2.3 1.4 6.2 5.4 0.6 0.8 1.3 0.1 1.6 3.7 1.3 0.8 1.2 2.6 1.2 1.7 0.1 1.4 0.4 1.8 1.7 0.8 2.2 3.3 3.6 2.8 2.3 4.3 3.1 2.8 2.8 2.3 3.4 5.6 10.9 3.2 7.3 21.2 7.8 2.3 4.0 2.9 2.2 12.2 5.5 2.9 4.2 4.3 4.5 3.7 4.2 2.1 8.2 6.8 1.9 4.0 0.9 4.6 6.0 6.5 9.6 10.3 11.7 5.2 2.4 6.5 7.1 4.8 3.8 9.4 5.3 3.0 1.8 1.7 17.2 4.8 4.1 3.1 3.7 0.6 7.5 3.3 0.0 17.8 3.3 4.7 5.2 38.2 44.7 3.3 7.3 2.6 5.8 5.4 1.3 1.4 5.5 7.3 0.0 12.3 4.9 7.6 10.5 3.1 0.6 1.4 5.8 4.2 3.8 3.8 ZNF7 "HF.16, KOX4" ENSG00000147789 "Zinc finger protein 7" P17097 8 144827464-144847509 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059090 Approved Approved Mitochondria NA NA "Cluster 42: Non-specific - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" Mitochondria "HPA059090: AB_2683901" "unprognostic (1.11e-1)" "unprognostic (4.47e-3)" "unprognostic (1.93e-1)" "unprognostic (1.36e-2)" "unprognostic (2.52e-1)" "unprognostic (2.97e-1)" "unprognostic (8.42e-3)" "unprognostic (3.15e-1)" "unprognostic (1.66e-1)" "unprognostic (1.33e-2)" "unprognostic (2.68e-1)" "unprognostic (7.95e-2)" "prognostic unfavorable (8.46e-8)" "unprognostic (1.15e-1)" "unprognostic (5.00e-1)" "unprognostic (5.43e-2)" "unprognostic (6.53e-2)" 18.4 14.1 10.4 10.7 11.0 14.4 18.3 18.6 12.8 20.2 10.7 18.2 10.4 18.0 15.2 14.8 17.5 10.5 14.3 10.5 9.8 18.3 15.5 14.5 15.0 11.6 10.8 19.4 17.4 15.3 16.8 14.3 11.1 20.5 12.7 13.9 16.4 13.6 26.6 21.1 17.2 12.7 9.0 21.7 15.2 17.0 11.2 15.9 19.3 17.5 15.6 18.3 17.2 13.4 16.7 22.2 21.4 21.1 17.9 27.2 19.6 17.4 22.0 23.1 19.7 11.4 20.9 23.1 19.9 19.0 12.6 14.2 19.5 25.4 25.1 15.4 16.2 41.3 30.6 13.3 20.7 12.1 18.5 26.1 30.3 18.1 44.2 22.4 14.5 19.2 41.9 16.1 26.0 27.3 33.0 13.1 21.8 22.0 26.6 22.6 19.0 18.4 16.1 22.6 21.0 25.6 38.1 21.6 21.3 20.4 26.1 19.1 16.4 17.3 30.9 13.2 16.9 13.0 9.9 25.0 18.0 15.4 21.7 34.3 10.7 10.9 13.5 10.0 16.9 18.1 15.4 12.0 12.2 17.4 20.1 13.8 10.4 16.6 19.2 9.6 16.3 9.2 10.4 11.0 18.6 12.8 10.5 9.8 11.6 10.8 11.1 9.0 11.2 13.4 11.9 19.2 11.6 6.2 16.4 7.0 18.2 12.7 8.6 34.2 9.1 8.0 11.4 7.2 11.3 3.7 29.2 17.3 16.6 6.6 5.9 14.1 18.4 6.3 10.4 10.6 9.6 15.6 11.3 11.2 12.9 14.7 10.2 7.7 3.8 16.7 15.0 8.2 9.1 28.6 10.7 9.1 6.1 9.0 11.1 4.9 17.7 10.2 8.8 3.7 12.9 20.0 22.6 10.6 11.4 13.7 5.6 15.8 7.8 18.6 12.4 7.1 9.2 30.1 6.6 19.3 10.4 44.1 26.7 9.1 9.2 19.4 16.9 19.8 10.2 13.8 ZNF710 "DKFZp547K1113, FLJ00306, FLJ37393" ENSG00000140548 "Zinc finger protein 710" Q8N1W2 15 90001324-90082206 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 44.2" "Cell type enhanced" "Detected in many" "Astrocytes: 38.8;Microglial cells: 149.9;Oligodendrocytes: 36.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 5.7" "Group enriched" "Detected in many" 6 "dendritic cells: 1.4;granulocytes: 1.9;monocytes: 5.7" "Cell line enhanced" "Detected in all" "SK-BR-3: 44.8" "Low region specificity" "Detected in all" "HPA030226, HPA030227, HPA030228" Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" Mitochondria Nucleoplasm "HPA030226: AB_2673384, HPA030227: AB_10599855, HPA030228: AB_10601899" "unprognostic (6.24e-2)" "unprognostic (7.07e-2)" "unprognostic (1.49e-2)" "unprognostic (2.40e-1)" "unprognostic (2.32e-1)" "unprognostic (1.36e-2)" "unprognostic (4.34e-2)" "unprognostic (8.45e-2)" "unprognostic (1.02e-1)" "unprognostic (1.49e-1)" "unprognostic (9.86e-2)" "unprognostic (1.57e-1)" "unprognostic (2.91e-3)" "unprognostic (1.03e-2)" "unprognostic (3.24e-2)" "unprognostic (1.65e-2)" "unprognostic (8.65e-2)" 3.6 4.3 12.0 14.7 13.0 8.7 5.4 6.4 11.2 6.3 3.1 8.3 9.1 5.3 5.0 17.1 5.2 7.0 10.0 6.9 8.8 5.7 5.3 9.8 10.0 12.2 13.6 4.8 44.2 3.3 4.5 5.7 12.9 7.5 6.9 1.2 9.6 4.3 33.4 12.6 8.0 3.4 10.4 14.2 10.2 1.7 12.4 5.6 6.2 1.5 6.5 7.7 9.2 11.5 9.2 10.7 20.1 7.6 2.7 4.0 10.5 9.4 8.8 6.8 8.6 7.7 8.3 9.3 4.3 9.1 6.4 6.2 5.1 13.5 3.8 6.0 9.4 17.1 4.6 13.1 5.5 5.0 25.6 6.6 7.2 14.6 7.9 3.2 11.8 10.0 5.8 6.2 2.6 23.7 11.1 13.9 15.8 11.3 6.9 13.5 4.5 10.2 2.7 11.4 18.3 12.3 12.5 44.8 6.4 5.2 9.6 17.2 17.1 13.9 6.8 4.2 7.4 5.0 2.7 9.0 10.6 14.6 7.4 0.0 1.6 1.2 0.2 3.5 0.2 0.1 0.1 0.2 1.2 0.1 0.4 0.4 1.9 0.2 5.7 1.4 0.5 0.7 12.0 13.0 6.4 11.2 6.9 8.8 12.2 13.6 12.9 10.4 12.4 11.5 1.7 3.2 8.2 38.8 2.7 5.4 4.7 2.8 1.8 1.4 7.1 3.6 12.1 4.3 6.3 11.0 2.1 2.3 6.8 7.7 0.0 3.6 0.8 4.0 4.1 4.3 4.8 2.5 10.2 6.1 3.0 3.1 7.1 6.2 1.3 2.1 5.7 1.6 11.6 3.3 12.0 8.1 0.0 15.8 33.5 5.5 2.5 15.7 1.8 149.9 13.3 1.4 2.1 22.1 36.4 10.1 11.5 3.0 3.8 8.5 2.3 0.8 3.6 0.9 6.6 1.6 3.0 0.3 2.5 4.3 7.5 2.3 2.5 2.0 6.5 13.7 ZNF782 FLJ16636 ENSG00000196597 "Zinc finger protein 782" Q6ZMW2 9 96816269-96875623 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 10 "Astrocytes: 96.3;Excitatory neurons: 105.1;Inhibitory neurons: 126.8;Microglial cells: 70.3;Oligodendrocyte precursor cells: 117.1;Oligodendrocytes: 166.0" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 9.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA011013 Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 21: Non-specific - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Mitochondria" "HPA011013: AB_1080758" "unprognostic (5.51e-2)" "unprognostic (5.29e-2)" "unprognostic (1.43e-1)" "unprognostic (1.49e-2)" "unprognostic (1.99e-1)" "unprognostic (1.48e-2)" "unprognostic (2.82e-2)" "unprognostic (9.89e-3)" "unprognostic (2.38e-2)" "unprognostic (3.04e-2)" "unprognostic (4.68e-3)" "unprognostic (3.63e-3)" "unprognostic (4.84e-2)" "unprognostic (3.55e-1)" "unprognostic (4.95e-1)" "unprognostic (2.61e-2)" "unprognostic (4.39e-2)" 1.6 1.6 2.1 2.3 1.3 1.3 3.0 9.3 3.0 2.4 0.1 2.0 2.3 2.9 3.5 1.6 2.4 1.8 1.1 1.5 1.0 2.6 1.7 1.4 2.6 0.9 0.7 3.3 4.6 3.2 1.8 2.0 1.4 3.0 2.8 9.0 2.2 2.3 2.2 3.9 2.8 2.1 0.1 2.2 2.7 6.1 1.5 3.2 3.2 2.0 3.0 1.6 1.9 3.4 2.1 1.7 4.2 5.9 1.0 1.0 2.5 1.8 1.5 2.4 1.8 1.8 3.3 3.7 2.3 1.4 3.5 3.6 2.9 1.1 2.8 4.2 1.7 3.2 3.8 1.8 1.4 5.3 3.2 0.6 2.5 2.6 1.6 1.9 1.3 5.7 4.8 5.0 2.0 3.6 4.7 2.4 3.0 3.4 2.7 5.4 4.9 1.3 2.2 1.1 3.8 2.7 2.5 1.6 1.8 2.7 2.8 2.5 2.0 3.5 2.6 3.8 2.1 4.9 3.5 2.2 2.2 2.0 2.7 0.0 0.2 0.0 0.3 0.1 0.5 0.1 0.1 0.2 0.0 0.4 0.2 0.1 0.2 0.2 0.0 0.1 0.1 0.0 2.1 1.3 9.3 3.0 1.5 1.0 0.9 0.7 1.4 0.1 1.5 3.4 3.4 0.0 4.1 96.3 3.3 1.9 1.4 0.6 4.0 5.9 2.3 2.2 1.6 1.5 0.3 1.8 8.4 0.9 5.1 1.7 0.0 1.4 7.5 2.9 3.9 3.6 0.0 7.4 105.1 1.7 0.4 2.3 2.0 5.2 5.7 6.0 3.6 1.1 1.2 3.3 126.8 1.9 0.0 0.6 0.7 9.2 1.8 1.7 0.0 70.3 4.0 1.7 1.0 117.1 166.0 1.0 0.3 3.0 4.6 1.9 2.4 1.8 1.2 7.6 0.0 5.0 3.1 10.6 2.3 2.1 1.0 0.7 2.9 3.3 1.1 2.0 ZNF787 ENSG00000142409 "Zinc finger protein 787" Q6DD87 19 56087366-56121295 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 110.5;Endometrial ciliated cells: 87.6;Rod photoreceptor cells: 71.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEK 293: 102.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035140 Supported Approved Nucleoplasm,Nucleoli,Mitochondria NA NA "Cluster 24: B-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "Nucleoli, Mitochondria" "HPA035140: AB_10602358" "unprognostic (1.97e-2)" "unprognostic (5.86e-2)" "unprognostic (8.77e-2)" "unprognostic (1.62e-1)" "unprognostic (1.08e-1)" "unprognostic (2.24e-1)" "unprognostic (1.46e-2)" "unprognostic (2.17e-1)" "unprognostic (3.19e-2)" "unprognostic (1.54e-1)" "unprognostic (4.83e-2)" "unprognostic (1.26e-1)" "unprognostic (1.27e-1)" "unprognostic (1.31e-2)" "unprognostic (1.86e-1)" "unprognostic (1.10e-1)" "unprognostic (1.96e-3)" 18.3 24.4 13.4 10.2 13.9 27.0 16.6 12.7 15.4 18.2 11.1 24.0 15.7 19.9 3.9 20.8 22.3 3.0 26.9 12.1 11.4 17.6 43.9 17.9 7.3 15.2 13.1 16.1 34.1 5.9 15.9 4.4 12.6 21.2 4.7 7.6 19.0 7.7 42.2 18.0 19.9 4.0 11.9 27.7 23.2 16.1 15.4 5.6 16.5 9.7 4.4 20.8 16.6 13.8 29.2 28.1 9.0 18.9 2.5 5.6 23.3 14.7 5.7 9.8 11.1 16.7 17.6 20.7 1.0 6.2 8.8 22.7 5.7 11.9 4.4 27.5 102.6 32.9 14.6 25.6 14.1 31.8 27.8 7.4 11.6 8.2 14.2 6.1 7.4 11.6 39.9 22.5 5.8 18.2 19.8 40.0 28.4 26.7 52.3 24.6 13.1 26.7 10.2 19.1 34.2 33.3 15.6 30.2 29.4 5.0 18.6 44.5 16.0 36.8 26.6 15.7 41.2 47.4 37.4 20.3 21.4 21.0 17.6 0.6 0.8 1.1 0.4 0.6 0.6 1.0 0.3 0.3 0.8 1.4 0.5 0.2 1.8 0.5 0.6 2.2 0.5 0.3 13.4 13.9 12.7 15.4 12.1 11.4 15.2 13.1 12.6 11.9 15.4 13.8 29.5 12.8 2.7 5.5 11.2 6.1 11.5 5.0 7.4 52.1 19.2 16.9 12.0 11.5 5.5 11.0 110.5 3.3 20.0 29.7 1.9 6.6 2.0 87.6 17.2 16.2 9.1 4.0 5.1 16.7 4.6 10.1 8.6 48.2 5.7 23.2 11.7 33.4 8.9 35.3 4.2 19.8 8.2 11.0 7.8 3.4 5.0 16.4 1.8 6.5 8.9 44.5 7.2 4.5 6.1 13.1 19.5 4.5 7.1 11.3 12.8 5.8 4.0 71.3 6.6 16.0 13.0 3.8 12.1 4.8 7.2 1.9 9.2 55.8 20.6 12.4 ZNF862 ENSG00000106479 "Zinc finger protein 862" O60290 7 149838375-149867479 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 51.2;Excitatory neurons: 44.0;Inhibitory neurons: 45.2;Microglial cells: 31.9;Oligodendrocyte precursor cells: 46.3;Oligodendrocytes: 58.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA024154 Uncertain Approved Mitochondria NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 51: Non-specific - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA024154: AB_1859469" "unprognostic (1.82e-2)" "unprognostic (2.33e-1)" "unprognostic (3.32e-3)" "unprognostic (1.97e-1)" "unprognostic (8.87e-2)" "unprognostic (4.87e-3)" "unprognostic (4.72e-3)" "unprognostic (2.74e-2)" "unprognostic (6.76e-2)" "unprognostic (2.56e-2)" "unprognostic (2.38e-3)" "unprognostic (4.73e-2)" "unprognostic (5.88e-2)" "unprognostic (4.29e-2)" "unprognostic (8.90e-2)" "unprognostic (1.30e-2)" "prognostic favorable (8.66e-4)" 5.6 7.0 8.1 6.8 8.6 5.6 7.7 8.9 8.4 8.9 13.0 8.6 4.4 7.5 11.7 6.1 9.6 7.2 6.2 7.7 8.4 9.2 7.6 6.4 9.5 8.5 7.6 9.7 11.4 10.9 10.4 3.8 8.2 9.0 6.9 9.9 11.7 7.9 6.5 16.7 8.7 6.5 7.0 10.1 7.8 4.2 8.6 12.3 13.6 6.2 9.2 7.4 6.3 10.8 3.3 3.5 7.8 12.3 8.8 9.5 0.2 6.7 6.8 2.2 3.6 0.4 8.6 1.5 8.6 7.7 3.0 2.2 2.3 3.3 1.6 5.0 3.4 1.5 2.9 0.0 7.9 2.4 1.4 10.7 11.8 2.2 3.4 9.7 5.3 9.1 1.7 6.1 4.0 8.5 2.8 6.2 2.6 6.3 3.5 5.1 1.0 9.2 6.2 2.0 3.1 10.3 5.8 4.2 5.8 3.7 3.2 2.9 9.6 5.5 0.2 12.7 2.5 9.4 5.5 1.5 9.5 6.3 6.4 0.0 1.1 0.7 3.2 2.0 0.8 1.8 1.1 1.6 1.4 0.5 1.3 1.2 0.1 0.8 0.7 1.4 0.9 1.0 8.1 8.6 8.9 8.4 7.7 8.4 8.5 7.6 8.2 7.0 8.6 10.8 2.6 0.0 1.5 51.2 6.4 0.8 0.6 1.8 13.6 5.7 4.4 4.1 4.0 2.8 2.9 7.3 12.5 1.1 1.5 1.6 1.9 1.9 1.3 2.9 2.6 3.2 1.8 3.4 44.0 1.4 0.3 6.0 5.6 3.4 4.5 5.2 1.8 3.0 1.0 10.1 45.2 2.0 2.0 1.0 0.4 1.5 1.5 3.2 0.0 31.9 1.5 2.7 0.0 46.3 58.4 1.3 1.9 2.2 3.3 1.6 2.2 0.9 3.2 6.0 0.0 3.7 2.6 1.3 2.3 7.7 1.3 2.6 9.3 2.7 2.2 0.7 ZNF875 HKR1 ENSG00000181666 "Zinc finger protein 875" P10072 19 37312837-37369365 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 141.0" "Cell type enhanced" "Detected in some" "Adipocytes: 5.1;Cardiomyocytes: 19.8;Cytotrophoblasts: 11.0;Extravillous trophoblasts: 5.7;Hofbauer cells: 7.3;Syncytiotrophoblasts: 9.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA036126, HPA044855" Approved Approved Nucleoplasm,Mitochondria No No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 77: Retina - Visual perception" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Mitochondria" "HPA036126: AB_10670708, HPA044855: AB_2679113" "unprognostic (1.04e-2)" "unprognostic (9.68e-2)" "unprognostic (1.75e-1)" "unprognostic (3.58e-1)" "unprognostic (2.78e-1)" "unprognostic (4.81e-2)" "unprognostic (2.29e-1)" "unprognostic (1.02e-3)" "unprognostic (4.92e-3)" "unprognostic (9.82e-2)" "prognostic favorable (4.41e-4)" "prognostic unfavorable (5.18e-5)" "unprognostic (1.34e-1)" "unprognostic (5.04e-2)" "unprognostic (2.00e-1)" "unprognostic (2.39e-1)" "unprognostic (1.20e-3)" 18.9 37.4 29.0 10.8 26.2 14.8 25.9 36.8 30.9 24.1 46.5 22.6 8.3 20.4 23.9 17.4 23.9 14.4 31.9 28.0 30.3 34.0 18.3 18.7 16.7 25.4 26.5 28.1 20.0 31.8 36.5 18.3 26.4 39.4 14.0 141.0 27.1 19.2 21.3 28.4 19.4 17.4 19.3 27.9 21.1 30.4 28.7 19.2 37.9 18.1 18.9 21.7 22.0 30.2 7.8 19.7 24.9 32.3 18.0 15.1 17.2 13.2 20.0 23.7 25.8 10.0 9.1 27.8 31.4 14.0 11.1 6.6 16.5 17.7 24.9 14.5 28.4 9.8 26.9 10.4 23.3 8.6 23.9 23.4 21.5 16.4 35.4 23.8 14.8 19.9 1.9 1.6 17.6 16.0 20.0 17.7 51.0 13.9 11.3 13.7 10.7 10.9 21.2 31.9 32.1 42.5 13.1 16.7 16.9 36.2 24.1 17.4 13.6 18.8 13.1 14.2 21.0 34.9 40.4 29.8 2.2 10.7 21.3 12.8 4.5 7.4 7.6 5.8 14.9 11.1 10.6 11.5 6.9 12.6 14.3 12.0 4.1 11.4 4.0 8.4 13.9 6.8 29.0 26.2 36.8 30.9 28.0 30.3 25.4 26.5 26.4 19.3 28.7 30.2 5.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 11.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 5.7 2.2 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 9.9 0.4 0.0 0.0 0.0 ZNFX1 "FLJ11277, KIAA1404" ENSG00000124201 "Zinc finger NFX1-type containing 1" Q9P2E3 20 49237946-49278426 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+ SV40 Large T+: 132.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046629 Approved Approved Mitochondria No No "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Mitochondria "HPA046629: AB_2616451" "unprognostic (1.03e-1)" "unprognostic (2.80e-1)" "unprognostic (1.15e-1)" "unprognostic (3.21e-2)" "unprognostic (1.21e-1)" "unprognostic (3.58e-1)" "unprognostic (2.62e-2)" "unprognostic (2.55e-1)" "unprognostic (3.85e-2)" "unprognostic (1.49e-1)" "unprognostic (3.13e-2)" "unprognostic (2.09e-1)" "unprognostic (1.50e-1)" "unprognostic (2.79e-1)" "unprognostic (8.71e-3)" "unprognostic (7.40e-2)" "unprognostic (7.86e-2)" 17.1 9.4 9.7 14.3 10.7 28.7 12.4 9.1 9.8 10.1 12.1 11.2 11.0 11.3 9.0 8.1 10.7 14.1 13.2 8.9 9.4 11.8 9.6 18.8 14.2 14.0 11.0 9.9 9.2 13.0 8.5 12.3 10.8 9.7 10.5 8.7 10.3 9.6 15.5 11.8 12.4 13.6 13.3 19.1 11.4 13.4 11.9 13.1 13.8 14.5 13.4 16.5 9.0 11.3 16.3 24.9 5.8 8.2 31.4 24.5 9.8 21.6 50.9 132.7 54.9 28.4 13.2 13.5 27.3 43.5 37.6 30.7 10.8 29.3 45.1 12.8 3.6 16.0 18.1 12.5 27.2 13.0 18.7 26.3 26.9 29.7 22.0 24.3 20.3 8.0 12.4 16.2 33.6 6.8 14.2 8.7 5.6 14.0 20.7 8.9 19.6 3.8 21.8 22.1 5.9 4.3 31.6 61.1 22.4 7.1 15.7 10.8 50.9 64.8 18.3 23.8 21.1 10.7 4.0 7.2 26.0 8.7 14.6 19.3 12.3 20.1 13.5 15.2 12.0 9.4 13.6 13.1 9.1 7.1 12.9 10.0 51.9 9.9 27.1 5.2 11.0 11.5 9.7 10.7 9.1 9.8 8.9 9.4 14.0 11.0 10.8 13.3 11.9 11.3 36.5 41.7 27.2 10.4 25.8 27.8 21.2 14.4 19.4 15.7 13.7 11.2 14.4 10.0 24.8 20.2 10.4 6.1 18.7 28.0 0.0 23.9 37.4 15.9 17.9 38.1 13.1 10.7 12.5 22.7 7.0 28.0 28.5 18.6 27.3 8.1 29.3 13.4 15.1 11.8 11.7 14.2 16.2 26.4 38.0 21.1 22.7 34.2 19.6 15.0 30.2 29.5 17.5 7.1 9.9 32.3 21.8 27.1 9.3 32.8 18.7 6.7 42.8 15.1 0.0 27.8 29.9 42.0 16.3 16.2 21.7 11.4 31.4 10.2 10.4 35.7 ZNHIT3 "Hit1, TRIP3" ENSG00000273611 "Zinc finger HIT-type containing 3" Q15649 17 36486629-36499310 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 222.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060019, HPA078211" Approved Approved Mitochondria NA NA "Cluster 30: Non-specific - Translation" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Mitochondria "HPA060019: AB_2684188, HPA078211: " "unprognostic (5.47e-2)" "unprognostic (1.29e-1)" "unprognostic (8.87e-2)" "unprognostic (1.20e-1)" "unprognostic (3.56e-2)" "unprognostic (1.56e-1)" "unprognostic (4.75e-3)" "unprognostic (6.03e-2)" "unprognostic (6.48e-3)" "unprognostic (2.55e-1)" "unprognostic (1.39e-1)" "unprognostic (1.93e-1)" "unprognostic (2.81e-2)" "unprognostic (1.47e-1)" "unprognostic (2.20e-1)" "unprognostic (1.84e-1)" "unprognostic (6.19e-2)" 27.4 32.4 33.4 17.6 34.9 31.2 32.7 33.6 43.1 26.2 31.3 30.9 24.1 24.6 39.9 30.4 24.0 20.1 27.2 33.9 35.1 35.1 35.9 19.4 39.1 33.5 34.0 31.1 33.1 27.4 24.0 21.0 33.9 26.3 30.5 19.5 26.3 20.0 58.0 30.9 24.1 18.9 35.2 25.5 28.2 50.4 33.4 29.4 28.7 32.4 39.7 30.0 26.5 35.6 39.6 39.0 70.4 55.1 38.6 49.4 38.8 35.8 56.0 53.6 55.2 6.9 55.7 67.3 38.8 18.0 66.8 37.1 25.7 30.8 66.5 35.3 25.7 27.2 41.1 54.3 28.2 73.0 37.7 34.4 69.0 22.1 53.6 60.3 37.1 79.6 48.5 39.8 58.3 36.0 98.3 92.5 50.1 38.0 38.0 33.0 71.2 56.1 67.7 35.2 57.6 42.7 42.7 26.3 73.0 59.5 76.3 72.7 36.4 25.2 42.6 50.9 54.3 41.3 57.6 68.8 54.6 44.3 50.5 15.7 14.5 10.3 15.5 11.3 32.4 22.6 27.1 21.5 20.0 21.6 33.9 27.6 7.9 23.8 26.5 20.0 27.2 17.2 33.4 34.9 33.6 43.1 33.9 35.1 33.5 34.0 33.9 35.2 33.4 35.6 29.0 25.6 27.0 7.5 48.3 46.4 34.1 99.9 38.1 25.4 51.2 75.2 11.8 30.0 47.5 33.1 12.5 93.2 58.1 24.4 88.0 61.1 222.2 37.9 29.9 32.3 43.5 33.9 10.9 51.2 98.5 30.9 21.4 32.3 34.2 48.5 25.4 30.4 67.4 15.2 12.7 33.8 42.7 49.4 36.7 79.1 37.0 34.6 53.4 10.3 66.6 42.5 47.4 12.1 14.7 60.9 36.8 44.4 32.4 47.3 50.6 88.1 33.8 28.3 46.0 36.6 37.5 179.1 71.2 37.2 43.8 77.2 58.3 55.9 44.6 34.0 ZZEF1 "FLJ10821, KIAA0399, ZZZ4" ENSG00000074755 "Zinc finger ZZ-type and EF-hand domain containing 1" O43149 17 4004445-4143030 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 115.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031778, HPA031790" Uncertain Approved Nucleoplasm,Mitochondria NA NA 1100000 "Cluster 10: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 45: Enterocytes - Digestion" Nucleoplasm Mitochondria "HPA031778: AB_10599831, HPA031790: AB_10600999" "unprognostic (4.48e-2)" "unprognostic (7.59e-2)" "unprognostic (6.75e-2)" "unprognostic (2.39e-2)" "unprognostic (1.43e-1)" "prognostic favorable (1.02e-4)" "unprognostic (2.80e-1)" "unprognostic (1.44e-2)" "unprognostic (1.23e-1)" "unprognostic (2.21e-2)" "prognostic favorable (6.08e-4)" "unprognostic (1.54e-1)" "unprognostic (1.38e-3)" "unprognostic (6.09e-3)" "unprognostic (1.80e-1)" "unprognostic (9.43e-2)" "unprognostic (6.46e-2)" 10.2 10.6 6.4 10.1 6.7 20.8 9.7 7.4 7.3 8.4 18.3 19.2 15.5 9.9 5.7 11.1 9.1 6.4 11.0 7.1 6.0 7.6 9.0 11.3 10.1 8.0 6.9 10.1 14.2 12.1 11.2 6.0 7.8 10.1 14.6 11.2 9.1 7.4 22.2 12.1 27.5 8.8 5.8 14.2 12.0 8.0 8.5 15.1 10.7 13.3 9.7 10.9 8.1 7.5 13.1 20.1 7.1 9.7 17.4 9.8 8.5 11.1 13.9 12.7 12.3 10.0 4.5 12.4 7.3 15.0 8.4 14.6 14.4 7.6 12.9 14.5 15.0 12.0 16.4 6.5 11.8 10.2 22.6 12.6 10.0 12.5 14.7 6.6 16.6 12.3 8.8 12.2 8.0 8.9 12.7 6.0 4.3 12.5 7.6 14.0 8.6 5.4 7.1 13.2 5.6 8.2 12.6 7.7 10.8 7.0 7.6 7.7 19.7 11.1 5.6 14.1 14.7 5.4 3.0 6.3 11.1 8.9 10.5 0.7 0.6 0.6 0.8 0.9 1.0 0.4 0.5 0.5 0.5 0.3 0.3 0.6 1.0 0.2 1.0 0.4 0.4 0.4 6.4 6.7 7.4 7.3 7.1 6.0 8.0 6.9 7.8 5.8 8.5 7.5 19.3 57.7 54.8 39.8 23.5 7.1 5.4 6.6 13.1 30.6 12.6 10.3 22.8 18.6 30.0 9.2 98.0 8.3 23.7 93.4 0.0 7.3 48.9 18.8 17.4 19.2 13.2 12.4 50.3 11.2 6.4 21.6 46.4 25.6 26.5 21.8 23.2 15.2 11.9 40.4 55.3 38.5 12.2 30.5 10.6 26.8 14.9 29.0 12.4 22.5 20.4 15.8 19.6 35.2 53.6 14.9 34.3 9.8 27.8 9.5 115.2 4.8 22.7 50.3 6.6 23.7 15.2 12.0 11.8 16.4 10.1 8.9 31.1 18.0 28.6 9.3