Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" AARS2 "AARSL, bA444E17.1, KIAA1270" ENSG00000124608 "Alanyl-tRNA synthetase 2, mitochondrial" Q5JTZ9 6 44298731-44313347 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, RNA-binding, tRNA-binding" "Cancer-related genes, Cardiomyopathy, Disease variant, Neurodegeneration, Premature ovarian failure, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035636, HPA061396" Approved Enhanced Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 23: Spermatids - Flagellum & Golgi organization" Mitochondria "HPA035636: AB_10670837, HPA061396: AB_2684502" "unprognostic (1.56e-1)" "unprognostic (3.24e-2)" "unprognostic (2.58e-2)" "unprognostic (2.04e-3)" "unprognostic (2.83e-1)" "unprognostic (1.69e-1)" "unprognostic (8.83e-3)" "unprognostic (5.12e-2)" "unprognostic (3.64e-2)" "unprognostic (1.38e-1)" "unprognostic (2.19e-2)" "unprognostic (1.37e-2)" "unprognostic (1.74e-1)" "unprognostic (1.84e-1)" "unprognostic (1.48e-1)" "unprognostic (1.08e-1)" "unprognostic (2.02e-1)" 4.7 5.2 6.5 5.6 6.2 5.4 4.9 9.4 6.7 7.6 6.7 5.8 6.5 6.1 3.2 9.2 6.4 4.6 6.0 6.8 5.1 5.7 6.9 4.3 6.0 6.1 5.8 8.3 6.5 5.9 6.3 4.1 6.4 7.0 4.1 5.4 6.2 4.3 4.8 7.2 7.9 4.1 5.4 7.2 5.4 3.7 6.0 6.2 6.2 3.3 5.3 5.6 7.4 6.7 14.6 9.9 13.9 23.8 8.1 7.2 18.3 10.9 5.7 11.2 10.6 11.4 7.1 16.3 16.2 4.8 12.2 10.0 14.7 16.0 4.7 10.9 23.7 18.9 10.6 14.5 4.8 17.9 16.0 5.9 9.8 9.0 10.2 7.3 9.5 21.8 21.0 15.4 6.2 16.0 14.2 15.9 9.9 40.3 9.8 16.4 8.7 10.4 6.7 12.7 32.0 11.4 9.4 10.9 15.5 9.7 9.9 21.6 8.4 12.1 13.5 7.6 13.9 8.8 8.7 16.5 6.8 15.9 22.1 2.2 1.1 0.1 1.3 1.3 2.1 1.5 1.9 1.7 1.0 2.9 1.8 1.7 0.2 1.9 1.4 1.3 1.2 1.3 6.5 6.2 9.4 6.7 6.8 5.1 6.1 5.8 6.4 5.4 6.0 6.7 2.6 6.4 3.3 5.2 3.7 0.6 2.1 1.9 4.0 6.6 2.8 2.7 3.5 5.7 2.8 0.0 12.5 5.0 4.9 3.0 0.0 2.3 10.1 3.5 5.4 3.0 0.0 8.2 5.5 0.4 5.0 3.4 5.1 6.2 0.0 5.9 3.9 2.5 3.3 0.0 9.0 2.2 2.0 2.8 1.8 1.0 4.7 2.5 0.0 1.9 3.9 2.0 4.1 3.0 3.6 1.4 0.7 4.5 6.9 1.6 6.3 1.0 3.0 7.1 0.0 4.7 2.8 4.3 6.1 4.4 0.4 5.3 4.1 4.5 3.7 1.6 ACAD9 "MGC14452, NPD002" ENSG00000177646 "Acyl-CoA dehydrogenase family member 9" Q9H845 3 128879596-128924003 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037716, HPA046720" Supported Enhanced Mitochondria No No "Cluster 14: Monocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA037716: AB_10673638, HPA046720: AB_2679773" "unprognostic (1.04e-1)" "unprognostic (1.28e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (3.05e-4)" "unprognostic (3.61e-1)" "unprognostic (2.83e-1)" "prognostic unfavorable (3.67e-6)" "unprognostic (1.30e-1)" "unprognostic (3.74e-1)" "unprognostic (3.25e-2)" "unprognostic (1.37e-1)" "unprognostic (6.96e-3)" "prognostic favorable (4.32e-8)" "unprognostic (1.52e-1)" "unprognostic (2.64e-2)" "unprognostic (6.56e-2)" "unprognostic (9.96e-2)" 16.7 20.5 9.0 6.1 8.5 4.7 14.5 9.6 10.2 14.4 9.1 13.6 9.0 14.6 7.7 23.2 12.9 7.3 21.9 8.3 8.7 15.6 20.6 11.0 6.6 8.2 8.7 12.9 14.4 27.7 14.6 8.4 8.4 12.1 9.4 4.1 14.2 12.0 30.4 48.0 11.2 11.1 7.4 12.2 15.9 12.5 8.7 12.1 13.6 28.7 11.2 12.9 14.5 9.0 46.2 22.6 18.0 12.6 28.7 20.7 17.5 22.4 26.2 43.6 36.8 33.3 27.1 33.3 21.1 29.5 29.0 35.5 33.8 45.9 32.8 21.2 23.1 29.3 46.8 24.4 21.6 23.9 10.6 22.5 16.8 23.6 26.7 25.1 35.8 25.2 14.4 11.4 29.5 46.5 36.7 19.0 9.9 49.3 33.8 25.5 17.4 35.1 30.9 25.1 19.0 11.6 37.0 32.9 23.2 17.4 44.5 54.8 18.2 13.2 13.4 14.2 20.3 14.5 5.8 28.3 28.3 21.4 22.7 2.4 15.1 4.9 8.3 18.3 7.8 8.1 7.6 7.3 17.5 5.4 6.2 8.0 0.7 6.8 25.2 9.9 8.3 12.1 9.0 8.5 9.6 10.2 8.3 8.7 8.2 8.7 8.4 7.4 8.7 9.0 10.4 16.0 21.7 13.1 9.3 6.2 11.4 16.7 8.6 14.1 11.9 9.5 30.5 15.7 14.8 14.7 10.4 26.2 10.5 11.7 21.5 20.6 20.2 10.4 11.5 11.2 5.4 14.3 14.3 17.8 18.8 12.9 16.8 12.9 16.5 12.0 15.7 26.7 31.5 10.1 17.7 7.4 16.2 9.5 4.0 17.3 10.2 10.8 16.0 7.5 13.4 15.0 12.3 6.0 12.2 14.1 8.7 14.7 9.5 8.1 9.4 26.3 12.0 11.9 13.1 12.7 14.9 22.6 9.6 13.5 14.2 30.6 8.2 18.1 14.3 8.4 ACADM "ACAD1, MCAD, MCADH" ENSG00000117054 "Acyl-CoA dehydrogenase medium chain" P11310 1 75724431-75787575 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 367.3;skeletal muscle: 380.0;tongue: 475.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 373.1;Distal tubular cells: 344.4;Hepatocytes: 261.2;Proximal tubular cells: 564.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 289.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006198, HPA026542" Enhanced Enhanced Mitochondria NA NA 930000 "Cluster 19: B-cells - Humoral immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA006198: AB_1078087, HPA026542: AB_1844469" "unprognostic (9.04e-3)" "unprognostic (2.36e-1)" "prognostic favorable (7.30e-4)" "unprognostic (5.09e-3)" "unprognostic (1.61e-3)" "unprognostic (5.68e-2)" "unprognostic (6.75e-2)" "unprognostic (1.11e-1)" "unprognostic (8.02e-2)" "unprognostic (4.95e-2)" "unprognostic (9.40e-3)" "unprognostic (3.35e-1)" "prognostic favorable (3.83e-8)" "unprognostic (1.27e-1)" "unprognostic (4.09e-2)" "unprognostic (3.56e-2)" "unprognostic (1.24e-1)" 81.9 82.2 25.2 24.3 25.0 17.3 69.9 26.6 42.2 29.3 30.4 46.8 103.9 20.0 25.3 51.3 30.6 27.8 217.8 24.3 25.9 295.9 367.3 22.6 42.6 26.9 26.8 35.7 35.9 66.3 19.2 16.9 25.8 26.8 49.5 21.2 31.4 26.2 380.0 14.4 75.6 25.5 26.2 27.4 52.8 35.7 25.8 29.7 38.4 475.9 44.3 32.7 21.3 25.2 25.8 20.5 61.0 26.8 53.1 42.1 17.5 48.1 40.4 46.1 38.5 38.3 39.5 289.1 40.7 34.4 39.0 22.8 54.9 41.8 57.8 113.0 25.5 94.4 58.5 58.3 36.4 80.0 23.9 50.7 23.5 39.8 22.8 35.0 36.2 56.6 102.3 60.4 50.5 9.6 96.3 40.6 50.2 80.4 49.5 118.8 83.8 30.6 77.9 70.7 33.8 43.0 38.0 111.6 102.0 43.1 32.7 107.6 20.2 29.9 29.6 26.6 78.1 38.6 62.0 128.1 25.8 67.0 35.3 15.3 14.2 19.3 17.1 20.9 27.3 40.7 17.8 21.5 21.4 24.6 20.3 23.6 0.5 25.0 20.4 23.2 19.5 19.5 25.2 25.0 26.6 42.2 24.3 25.9 26.9 26.8 25.8 26.2 25.8 25.2 42.9 57.7 58.3 29.7 56.5 27.3 41.8 69.0 44.3 39.0 49.0 40.9 373.1 52.9 63.0 58.8 25.0 35.8 39.4 42.6 344.4 37.9 55.4 27.1 32.2 36.2 40.7 67.6 51.6 26.5 19.5 47.6 26.0 25.4 44.9 61.5 43.9 261.2 75.7 30.3 46.7 38.7 63.1 45.6 22.2 24.4 46.9 38.2 51.6 19.7 32.8 53.7 29.9 36.2 36.0 21.2 49.7 45.5 74.9 24.2 88.0 564.8 106.7 30.0 0.0 38.6 43.7 76.3 86.1 46.6 27.0 15.3 39.4 72.5 46.7 35.9 ACAT1 "ACAT, THIL" ENSG00000075239 "Acetyl-CoA acetyltransferase 1" P24752 11 108116695-108147603 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 622.7;liver: 969.5" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 508.4;Distal tubular cells: 698.5;Hepatocytes: 663.4;Proximal tubular cells: 1484.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 420.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004428, HPA007569" Enhanced Enhanced Mitochondria NA NA 1400000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA004428: AB_1078088, HPA007569: AB_1844482" "unprognostic (3.70e-3)" "unprognostic (2.23e-2)" "unprognostic (7.84e-3)" "unprognostic (4.65e-2)" "unprognostic (3.05e-2)" "unprognostic (1.12e-1)" "prognostic favorable (1.43e-5)" "unprognostic (3.59e-3)" "unprognostic (1.26e-1)" "unprognostic (5.20e-2)" "unprognostic (2.64e-2)" "unprognostic (1.13e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.96e-1)" "unprognostic (1.68e-1)" "unprognostic (8.06e-2)" "unprognostic (6.62e-3)" 135.4 151.3 45.2 24.3 45.3 38.4 56.9 47.1 60.1 41.0 91.8 96.3 103.9 44.0 34.1 45.0 39.1 25.6 289.4 42.7 46.8 622.7 969.5 43.7 28.2 44.8 45.2 64.7 110.6 95.9 30.9 24.7 45.2 45.6 85.6 26.2 104.1 60.2 461.1 45.3 53.2 57.1 46.7 29.3 81.9 66.3 45.6 19.1 65.5 410.8 29.7 44.1 34.6 47.7 76.9 57.7 48.2 139.3 155.9 138.7 25.1 71.7 78.8 77.7 91.7 168.1 77.3 41.3 116.8 83.6 119.7 78.1 142.3 70.3 83.3 84.9 114.6 117.4 64.6 163.9 107.6 112.9 64.9 124.6 77.1 69.2 127.4 91.5 85.0 92.3 172.1 61.8 128.6 45.8 57.4 122.4 48.2 103.1 135.0 88.1 96.9 420.4 114.7 50.4 75.7 88.1 111.6 152.7 83.0 37.0 132.2 97.6 87.4 83.2 44.5 73.5 88.8 18.9 57.8 77.7 37.6 233.1 59.6 1.4 17.1 4.7 25.3 25.5 29.9 29.2 28.8 30.0 33.5 13.8 25.5 22.4 1.8 13.4 27.8 11.3 35.7 23.4 45.2 45.3 47.1 60.1 42.7 46.8 44.8 45.2 45.2 46.7 45.6 47.7 50.5 54.5 91.8 17.9 37.2 43.1 52.2 48.9 23.9 30.1 34.6 29.6 508.4 78.6 33.5 104.8 27.1 39.9 29.2 125.0 698.5 43.1 345.7 62.2 42.1 62.5 30.0 74.7 35.1 60.5 41.5 57.1 29.0 25.7 27.8 48.6 99.2 663.4 97.9 38.7 37.8 38.5 97.6 73.6 27.8 65.3 66.5 39.1 58.7 30.0 50.1 39.1 25.7 22.6 26.5 33.8 93.8 82.4 52.7 27.8 51.4 1484.0 101.8 28.8 65.7 54.2 69.2 172.7 27.2 39.2 48.4 25.2 38.1 61.6 84.5 24.4 ALDH18A1 "GSAS, P5CS, PYCS, SPG9" ENSG00000059573 "Aldehyde dehydrogenase 18 family member A1" P54886 10 95605941-95656711 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Proline biosynthesis" "Kinase, Multifunctional enzyme, Oxidoreductase, Transferase" "Disease variant, Hereditary spastic paraplegia, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 120.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 80.5;Granulosa cells: 81.6;Proximal enterocytes: 79.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008333, HPA012604" Approved Enhanced Mitochondria NA NA 48000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "HPA008333: AB_1078125, HPA012604: AB_1844721" "unprognostic (5.97e-3)" "unprognostic (2.08e-2)" "unprognostic (5.75e-2)" "prognostic favorable (4.20e-4)" "unprognostic (1.60e-2)" "unprognostic (1.06e-1)" "unprognostic (8.30e-3)" "unprognostic (7.08e-2)" "unprognostic (4.06e-2)" "unprognostic (8.04e-2)" "unprognostic (1.30e-1)" "unprognostic (1.81e-1)" "prognostic unfavorable (3.60e-9)" "unprognostic (1.02e-3)" "unprognostic (6.57e-2)" "unprognostic (1.29e-3)" "unprognostic (6.43e-2)" 15.3 16.1 12.2 21.2 12.6 16.7 20.2 12.4 13.1 33.4 21.0 51.9 89.3 18.5 30.9 21.0 21.9 25.2 11.5 12.2 13.6 17.7 24.3 10.8 22.0 12.4 14.7 16.7 61.8 33.5 28.2 26.3 13.1 24.2 49.3 11.4 120.1 24.9 4.3 22.4 73.1 26.3 12.7 12.1 40.5 11.7 14.0 17.2 37.5 5.5 26.9 25.2 14.3 13.1 66.5 61.6 57.9 152.7 76.0 72.9 62.2 75.6 112.8 75.1 93.7 124.4 51.6 223.7 68.9 119.7 36.2 85.6 117.1 77.8 84.6 64.0 92.0 71.2 40.5 177.9 49.7 125.6 76.1 77.0 46.8 61.5 119.1 124.5 79.9 82.6 67.5 46.0 57.1 95.0 114.5 80.5 68.6 109.2 60.7 105.9 66.3 76.9 88.3 49.7 57.5 56.9 60.1 47.1 56.9 66.0 70.5 57.9 66.7 31.1 49.0 80.9 88.2 52.4 41.7 135.8 60.4 142.8 40.7 0.1 2.6 0.2 27.3 5.2 28.7 23.0 24.5 28.3 9.6 16.1 20.7 23.1 0.5 26.3 8.3 5.9 25.8 15.5 12.2 12.6 12.4 13.1 12.2 13.6 12.4 14.7 13.1 12.7 14.0 13.1 4.6 6.4 9.2 7.2 12.6 11.2 8.3 8.9 14.2 6.3 15.6 12.4 4.6 11.5 14.3 20.2 0.0 43.9 6.7 80.5 1.9 13.7 1.3 12.7 18.1 8.0 19.8 17.9 15.7 21.1 31.6 16.2 18.8 16.9 8.2 81.6 5.3 27.3 11.5 10.1 13.6 41.3 8.2 3.5 3.8 1.6 9.3 3.5 16.0 11.2 2.6 7.1 8.2 17.6 12.8 11.7 56.4 12.0 30.1 18.4 79.4 8.4 15.2 3.4 0.0 10.5 10.1 8.2 9.9 17.6 8.1 30.2 9.0 10.8 38.7 9.4 ALDH1L2 "FLJ38508, mtFDH" ENSG00000136010 "Aldehyde dehydrogenase 1 family member L2" Q3SY69 12 105019784-105107643 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "One-carbon metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "pancreas: 40.7;salivary gland: 13.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 23.1;Inhibitory neurons: 24.0;Oligodendrocyte precursor cells: 25.1;Plasma cells: 14.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 62.8;ASC TERT1: 85.2;fHDF/TERT166: 102.4;HHSteC: 55.6;HSkMC: 69.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039481, HPA059282" Approved Enhanced Mitochondria No No "Cluster 25: Pancreas - Digestion" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Mitochondria "HPA039481: AB_10795465, HPA059282: AB_2732633" "unprognostic (5.99e-2)" "unprognostic (1.42e-1)" "unprognostic (1.10e-1)" "unprognostic (1.36e-3)" "unprognostic (1.76e-1)" "unprognostic (8.86e-2)" "unprognostic (1.75e-1)" "unprognostic (2.92e-1)" "unprognostic (5.74e-2)" "unprognostic (1.51e-1)" "unprognostic (1.01e-1)" "unprognostic (1.61e-1)" "unprognostic (8.19e-8)" "unprognostic (3.21e-3)" "unprognostic (1.33e-1)" "unprognostic (2.53e-3)" "unprognostic (2.52e-5)" 3.7 0.6 1.3 3.1 1.2 0.6 2.3 2.3 1.6 5.3 0.7 2.2 2.6 2.0 1.0 1.3 1.5 2.8 1.9 1.1 1.6 0.4 0.2 1.8 1.0 1.4 1.3 0.6 40.7 0.6 1.3 1.1 1.5 3.6 2.3 0.7 13.0 4.6 0.8 1.0 1.4 4.2 1.8 0.7 3.3 1.1 1.6 0.5 2.1 1.2 1.7 3.4 1.5 2.5 13.0 1.3 0.7 27.3 62.8 85.2 1.6 40.8 26.0 5.2 13.5 1.6 0.0 0.0 1.6 102.4 0.2 0.1 0.1 1.0 6.5 0.0 0.3 0.8 0.1 3.4 55.6 5.3 0.1 69.7 3.1 13.6 25.2 0.0 3.0 0.2 2.1 37.7 10.6 0.0 0.0 0.3 1.6 0.0 0.3 0.0 0.1 4.3 0.0 0.0 9.4 4.5 0.0 8.3 20.5 0.4 6.0 44.0 0.3 3.9 3.8 0.0 2.2 45.5 12.8 0.1 16.2 19.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 1.2 2.3 1.6 1.1 1.6 1.4 1.3 1.5 1.8 1.6 2.5 1.4 0.0 0.6 3.3 2.6 0.5 0.1 0.7 0.0 1.7 0.3 1.1 1.6 0.0 0.2 0.0 0.0 0.2 1.5 0.1 0.0 0.3 4.1 0.7 8.5 0.9 0.0 0.0 23.1 9.8 0.6 10.5 1.5 1.6 0.0 0.1 1.1 0.0 0.4 5.0 24.0 0.0 0.0 0.6 1.7 5.9 3.7 1.0 5.4 1.0 4.0 1.3 0.0 25.1 8.5 3.7 0.0 6.8 14.6 0.4 0.0 0.1 0.2 0.8 0.0 3.6 8.4 1.7 0.1 0.0 0.6 0.3 0.9 0.1 0.1 0.2 ALDH6A1 MMSDH ENSG00000119711 "Aldehyde dehydrogenase 6 family member A1" Q02252 14 74056847-74084492 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "kidney: 379.1;liver: 367.1" "Cell type enhanced" "Detected in all" "Distal tubular cells: 201.5;Hepatocytes: 523.6;Proximal tubular cells: 962.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 43.2" "Lineage enriched" "Detected in all" 4 "granulocytes: 43.2" "Cell line enhanced" "Detected in all" "T-47d: 57.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029072, HPA029073, HPA029074, HPA029075" Enhanced Enhanced Mitochondria No No 37000 "Cluster 2: Granulocytes - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA029072: AB_10599176, HPA029073: AB_10601877, HPA029074: AB_10601000, HPA029075: AB_10602005" "unprognostic (1.45e-1)" "unprognostic (5.38e-2)" "unprognostic (6.89e-2)" "unprognostic (6.95e-3)" "unprognostic (1.46e-1)" "unprognostic (7.93e-2)" "unprognostic (1.11e-3)" "prognostic favorable (4.22e-4)" "unprognostic (1.58e-1)" "unprognostic (9.10e-2)" "unprognostic (3.11e-2)" "unprognostic (2.13e-1)" "prognostic favorable (2.00e-15)" "unprognostic (4.59e-1)" "unprognostic (1.92e-1)" "unprognostic (6.05e-3)" "unprognostic (1.12e-1)" 38.7 14.7 58.6 4.8 66.0 3.3 14.4 58.8 59.3 17.3 61.4 15.2 26.6 11.4 9.8 9.8 12.8 9.4 40.3 51.0 54.0 379.1 367.1 9.4 5.1 63.3 54.0 28.3 23.4 37.0 6.6 7.6 55.6 25.4 15.8 15.2 19.8 16.1 27.5 6.2 23.4 9.0 56.4 5.4 24.0 17.1 69.8 5.7 28.3 34.8 5.3 11.4 7.0 62.6 8.9 7.8 11.0 23.5 39.3 19.2 17.5 6.3 11.8 6.8 11.5 17.3 10.2 10.5 13.6 13.5 5.3 4.8 24.9 7.0 14.5 9.5 3.5 5.1 8.0 19.2 45.0 2.7 2.4 28.2 12.0 8.7 20.7 17.0 12.0 23.7 8.1 14.7 4.6 36.2 7.6 4.0 8.7 32.6 5.2 15.1 11.2 14.6 9.2 5.8 4.4 7.0 21.0 21.9 5.7 18.0 57.5 9.6 3.8 7.4 9.0 11.7 2.4 9.3 18.9 10.2 9.9 3.2 7.3 29.1 6.2 43.2 6.9 4.8 10.6 7.2 7.8 8.4 9.2 6.1 9.9 7.0 2.4 9.7 4.2 5.3 6.1 4.9 58.6 66.0 58.8 59.3 51.0 54.0 63.3 54.0 55.6 56.4 69.8 62.6 15.4 38.5 60.4 24.5 11.8 9.2 26.8 10.0 20.5 20.6 28.4 18.9 81.4 67.2 22.9 66.2 4.2 31.0 7.1 18.9 201.5 11.6 23.4 26.2 27.5 27.0 16.9 28.6 5.5 3.1 14.8 25.9 34.7 90.2 7.6 27.1 87.4 523.6 17.7 11.8 10.0 39.3 8.2 26.5 8.9 19.0 28.9 13.4 24.9 1.9 15.8 98.5 9.2 12.5 23.4 4.1 16.3 48.2 8.0 27.6 55.3 962.4 15.4 17.0 13.1 25.6 16.9 11.0 4.2 25.2 7.4 30.6 11.0 10.2 35.7 17.2 ARMC10 "MGC3195, SVH" ENSG00000170632 "Armadillo repeat containing 10" Q8N2F6 7 103074881-103099759 "Predicted intracellular proteins, Predicted membrane proteins" "Growth regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011036, HPA011057" Enhanced Enhanced Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 50: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA011036: AB_1080139, HPA011057: AB_1080137" "unprognostic (7.03e-3)" "unprognostic (2.44e-1)" "unprognostic (8.18e-2)" "unprognostic (3.53e-1)" "prognostic unfavorable (8.90e-6)" "unprognostic (3.85e-3)" "prognostic unfavorable (3.58e-4)" "unprognostic (5.57e-2)" "unprognostic (3.49e-2)" "unprognostic (7.90e-2)" "prognostic unfavorable (2.49e-6)" "unprognostic (1.02e-1)" "unprognostic (5.78e-2)" "unprognostic (1.47e-1)" "unprognostic (2.76e-1)" "unprognostic (1.14e-2)" "unprognostic (5.67e-2)" 20.9 22.8 11.2 9.3 11.9 7.2 18.1 10.5 12.7 22.3 12.2 19.4 9.8 17.8 17.0 21.0 18.6 11.3 16.6 11.4 11.9 24.0 24.4 15.5 10.8 10.7 11.4 24.4 24.4 17.2 11.9 10.9 11.4 18.0 12.7 13.8 16.4 15.7 18.4 25.8 12.1 14.4 13.7 12.3 19.8 12.2 11.6 13.6 17.6 8.6 11.5 21.3 19.5 15.9 30.1 25.5 16.1 28.8 30.0 28.4 15.1 19.3 22.2 14.7 17.4 13.7 34.8 57.3 42.4 18.0 43.4 25.6 20.9 23.3 20.9 19.2 22.3 19.4 10.9 7.8 31.9 55.8 21.3 19.3 40.4 18.8 30.2 45.7 33.6 29.6 45.9 32.8 26.5 58.8 38.8 43.9 36.2 54.5 26.8 22.9 15.5 69.2 37.7 20.8 16.3 25.1 30.3 43.8 35.3 26.9 17.6 26.9 23.4 22.9 23.6 52.0 31.8 47.8 77.6 42.9 25.5 50.1 30.2 0.0 2.3 3.8 1.4 3.1 2.2 2.2 2.2 2.2 3.4 3.0 2.3 2.4 0.5 2.1 1.6 3.1 2.4 1.1 11.2 11.9 10.5 12.7 11.4 11.9 10.7 11.4 11.4 13.7 11.6 15.9 30.1 25.6 17.9 12.1 31.8 78.8 60.2 7.9 54.7 24.4 53.3 56.1 17.4 34.3 12.4 27.6 14.6 45.3 41.1 17.6 66.5 19.7 12.6 31.4 32.3 28.4 15.0 51.5 20.7 15.5 52.2 35.4 33.6 23.8 17.2 37.9 30.4 37.6 46.7 8.4 18.5 32.6 6.1 38.8 39.5 8.3 33.8 32.7 46.2 14.0 28.7 38.3 25.7 20.6 44.0 23.2 20.5 34.3 41.9 87.1 21.9 97.4 10.5 28.6 32.9 28.6 37.5 15.6 35.1 67.2 104.3 45.0 31.4 31.9 41.3 71.9 ATAD3A FLJ10709 ENSG00000197785 "ATPase family AAA domain containing 3A" Q9NVI7 1 1512162-1534685 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058968, HPA064867, HPA065305" Approved Enhanced Mitochondria NA NA 27000 "Cluster 27: Non-specific - Gene expression" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA058968: AB_2683864, HPA064867: AB_2685375, HPA065305: AB_2685459" "unprognostic (8.42e-2)" "unprognostic (1.67e-1)" "unprognostic (3.11e-1)" "unprognostic (1.46e-1)" "unprognostic (2.50e-1)" "unprognostic (8.74e-2)" "prognostic unfavorable (5.90e-5)" "unprognostic (6.62e-2)" "unprognostic (9.53e-2)" "unprognostic (5.81e-2)" "unprognostic (4.09e-2)" "unprognostic (7.66e-2)" "unprognostic (1.17e-2)" "unprognostic (1.11e-1)" "unprognostic (3.09e-1)" "unprognostic (6.25e-2)" "unprognostic (1.87e-3)" 10.9 13.6 8.3 12.3 8.4 18.1 10.7 8.5 11.1 10.6 9.7 11.2 11.4 12.8 2.0 17.2 10.4 4.4 15.5 9.0 7.7 10.6 18.5 10.0 10.4 8.4 8.2 8.4 19.5 5.2 14.6 6.6 8.0 9.5 3.0 2.0 13.4 5.5 28.8 14.3 9.8 3.8 7.5 11.7 12.9 9.3 8.2 6.2 9.6 8.3 4.7 11.4 10.7 8.3 79.2 47.9 18.0 49.3 8.3 10.6 45.6 62.9 16.8 52.7 32.1 127.2 52.8 45.9 41.5 24.9 19.7 65.8 27.5 36.5 9.2 42.7 110.3 75.0 131.9 97.0 17.3 112.5 42.7 12.8 11.2 44.2 16.2 6.1 23.2 44.2 120.1 27.3 19.7 64.5 83.1 95.2 40.9 25.9 91.5 88.5 35.7 91.9 14.7 40.3 91.8 35.3 39.8 58.1 53.0 5.9 24.8 55.7 32.6 52.5 45.0 85.8 79.2 45.6 52.6 172.7 54.2 160.5 25.4 0.5 1.8 0.6 1.5 1.5 1.0 1.4 1.5 1.7 2.2 1.5 1.3 0.6 0.1 2.5 3.4 2.2 1.5 1.1 8.3 8.4 8.5 11.1 9.0 7.7 8.4 8.2 8.0 7.5 8.2 8.3 8.5 3.2 9.0 10.7 11.7 20.4 11.2 5.9 8.0 10.5 11.6 8.3 9.5 8.6 6.4 7.3 6.2 21.6 10.0 18.8 7.9 22.5 9.5 14.7 9.3 11.8 13.8 28.4 8.8 21.3 43.4 10.4 13.7 8.7 8.9 21.9 4.6 12.5 22.4 23.5 8.3 19.6 14.2 7.5 12.5 10.1 5.6 7.7 16.0 6.5 5.9 10.9 6.2 4.5 6.1 25.3 5.2 7.9 27.5 38.3 13.8 12.8 7.9 9.4 0.0 9.4 14.8 5.8 20.1 17.4 24.3 19.7 7.7 35.6 27.7 15.7 ATAD3B "KIAA1273, TOB3" ENSG00000160072 "ATPase family AAA domain containing 3B" Q5T9A4 1 1471765-1497848 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "HPA058968, HPA064867, HPA065305" Approved Enhanced Mitochondria NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA058968: AB_2683864, HPA064867: AB_2685375, HPA065305: AB_2685459" "unprognostic (6.05e-2)" "unprognostic (1.95e-1)" "unprognostic (6.54e-2)" "unprognostic (1.30e-1)" "unprognostic (1.97e-2)" "unprognostic (3.68e-1)" "prognostic unfavorable (1.81e-5)" "unprognostic (1.51e-1)" "unprognostic (2.27e-2)" "unprognostic (2.17e-2)" "unprognostic (8.24e-3)" "unprognostic (3.13e-2)" "prognostic unfavorable (5.48e-9)" "unprognostic (2.38e-2)" "unprognostic (2.80e-1)" "unprognostic (3.00e-2)" "unprognostic (1.68e-1)" 9.1 10.0 5.7 3.6 5.8 5.0 8.5 5.5 9.7 9.8 5.8 9.1 2.4 7.2 0.0 12.4 9.1 0.7 8.0 5.6 5.6 13.7 15.7 8.6 3.5 5.9 5.5 10.2 9.7 0.4 13.6 1.3 5.9 11.7 0.3 0.1 7.5 0.7 6.2 10.7 9.2 0.5 5.3 14.1 8.7 10.8 6.0 2.3 9.6 0.2 0.7 9.9 8.6 6.1 13.4 0.1 3.2 21.9 1.3 1.4 29.0 20.7 4.8 20.7 15.7 47.8 38.6 16.9 6.7 7.9 13.4 21.8 28.1 13.6 4.7 16.3 29.0 12.2 32.9 31.9 5.3 20.4 14.3 4.7 0.7 35.9 1.5 0.0 7.6 7.1 37.2 3.2 8.1 5.4 26.3 28.7 44.1 9.8 51.7 21.5 6.3 12.0 6.2 7.7 15.6 13.2 14.0 18.7 20.2 2.4 2.4 7.5 7.5 4.5 12.0 32.4 23.0 12.2 18.5 45.7 17.7 35.1 5.8 0.2 0.2 0.4 0.4 1.1 0.5 0.1 0.3 0.4 0.2 0.0 0.1 0.0 0.0 0.0 0.6 0.1 0.0 0.1 5.7 5.8 5.5 9.7 5.6 5.6 5.9 5.5 5.9 5.3 6.0 6.1 8.6 6.4 22.1 17.6 9.4 26.3 7.8 5.2 10.2 16.0 9.3 7.1 5.9 8.6 7.5 9.2 20.9 15.3 12.9 17.8 1.9 7.7 3.6 10.1 7.8 8.2 7.2 7.6 13.3 7.9 40.3 8.7 23.9 10.2 11.4 16.7 4.2 7.6 12.4 13.5 12.9 13.8 6.1 4.7 12.3 3.8 4.4 7.9 10.6 8.4 5.4 5.8 1.0 4.5 8.3 11.3 9.7 3.0 22.8 14.4 6.7 2.6 8.3 17.1 6.6 8.3 10.2 5.4 10.6 11.1 23.4 17.8 9.9 15.0 20.6 10.8 ATP5F1B "ATP5B, ATPSB" ENSG00000110955 "ATP synthase F1 subunit beta" P06576 12 56638175-56645984 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 2590.4;tongue: 3205.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 821.1;Distal tubular cells: 1238.5;Extravillous trophoblasts: 592.7;Hofbauer cells: 608.9;Proximal tubular cells: 951.7;Syncytiotrophoblasts: 1138.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001520, HPA001528, CAB017527" Enhanced Enhanced Mitochondria NA NA 19000000 "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 7: Non-specific - Mitochondria" Mitochondria "CAB017527: AB_1121153, HPA001520: AB_1078243, HPA001528: AB_1078242" "prognostic unfavorable (7.17e-6)" "unprognostic (5.69e-2)" "unprognostic (1.08e-2)" "unprognostic (7.24e-2)" "unprognostic (8.39e-2)" "unprognostic (1.84e-2)" "unprognostic (2.12e-3)" "unprognostic (1.92e-2)" "unprognostic (8.19e-3)" "unprognostic (2.38e-2)" "unprognostic (1.44e-2)" "unprognostic (2.11e-2)" "prognostic favorable (1.43e-9)" "unprognostic (2.79e-1)" "unprognostic (3.22e-1)" "unprognostic (1.33e-1)" "unprognostic (3.30e-2)" 432.7 555.5 217.6 300.5 231.4 465.8 301.5 281.6 303.8 241.8 443.3 741.6 689.5 235.4 223.4 527.6 277.9 225.7 2011.6 233.0 307.1 945.9 609.3 253.4 294.6 264.2 242.9 200.2 301.7 1311.6 252.6 301.4 280.4 280.9 767.6 484.2 407.7 356.4 2590.4 398.6 575.5 332.5 230.9 272.5 494.9 236.0 277.5 390.9 342.8 3205.3 458.3 404.1 311.2 244.7 693.6 834.9 632.3 1003.6 578.3 596.7 1159.8 683.2 645.6 1179.1 663.9 1375.7 755.6 1236.3 723.0 863.5 482.9 906.1 1378.1 851.5 1039.4 579.9 987.5 1333.1 726.4 872.5 716.6 1509.7 912.9 755.1 843.3 918.0 1171.2 870.2 985.8 901.7 1246.3 1363.1 992.2 671.5 1134.4 941.3 1085.9 905.6 1637.6 1079.3 711.0 1603.5 1315.6 1196.7 737.5 658.2 1042.3 1481.3 1214.0 663.4 1404.1 1151.8 657.6 454.8 507.9 671.9 751.0 659.5 865.7 1254.8 684.7 1007.8 718.4 403.5 549.4 281.8 293.5 643.6 326.3 303.2 275.4 313.6 713.4 248.4 221.0 266.8 137.1 296.9 750.6 360.9 372.9 1077.1 217.6 231.4 281.6 303.8 233.0 307.1 264.2 242.9 280.4 230.9 277.5 244.7 172.3 134.6 173.2 0.0 48.6 0.0 0.0 0.0 0.0 0.0 176.8 149.1 0.0 0.0 81.1 277.7 0.0 821.1 141.5 0.0 1238.5 517.7 0.0 194.1 169.2 115.7 0.0 0.0 0.0 367.9 592.7 115.0 0.0 163.3 145.1 267.6 0.0 0.0 608.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 136.3 0.0 0.0 281.2 0.0 0.0 0.0 0.0 333.3 0.0 0.0 26.8 0.0 0.0 951.7 102.7 0.0 0.0 0.0 151.1 0.0 0.0 0.0 0.0 1138.6 77.4 518.4 0.0 0.0 ATP5IF1 "ATPI, ATPIF1, ATPIP, IP, MGC1167, MGC8898" ENSG00000130770 "ATP synthase inhibitory factor subunit 1" Q9UII2 1 28236109-28246906 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 1035.0;Endometrial ciliated cells: 1524.2;Exocrine glandular cells: 672.1;Granulosa cells: 1030.6;Proximal tubular cells: 1502.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027999 Supported Enhanced Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "HPA027999: AB_10600984" "unprognostic (2.80e-2)" "unprognostic (3.72e-2)" "unprognostic (2.95e-1)" "prognostic favorable (6.38e-8)" "unprognostic (2.04e-1)" "unprognostic (1.76e-1)" "unprognostic (6.57e-2)" "unprognostic (2.93e-2)" "unprognostic (1.40e-2)" "prognostic favorable (8.20e-4)" "unprognostic (5.94e-2)" "unprognostic (3.52e-1)" "unprognostic (6.15e-3)" "unprognostic (4.68e-2)" "unprognostic (2.02e-1)" "unprognostic (2.79e-1)" "unprognostic (1.48e-3)" 96.9 215.1 98.4 50.6 98.6 144.3 108.8 95.6 140.0 123.3 95.2 234.8 163.1 113.0 44.5 184.5 139.4 28.0 585.8 100.0 106.5 384.9 342.6 116.0 64.5 99.6 96.8 134.9 163.4 90.1 246.5 37.6 97.8 156.0 59.4 71.0 145.3 37.1 456.7 165.0 199.6 28.5 93.7 153.7 215.7 355.5 99.6 60.0 169.2 179.8 47.9 116.6 134.0 104.1 271.9 136.4 79.3 75.1 58.0 62.7 94.1 118.6 57.9 98.6 96.2 132.0 192.5 189.1 173.8 72.1 37.6 161.5 91.2 118.0 77.6 143.9 306.0 162.9 612.7 180.8 62.9 125.5 158.1 73.5 190.2 88.2 70.4 96.2 95.7 222.0 292.9 167.9 71.2 178.0 187.6 230.4 262.7 100.9 167.8 177.3 87.5 270.2 196.9 175.5 158.9 114.2 146.5 150.8 160.4 76.5 224.4 136.6 100.6 31.9 88.0 126.5 142.1 432.0 282.8 268.6 151.1 338.8 38.1 133.3 116.6 126.1 144.2 111.1 145.8 195.2 154.3 155.5 142.8 154.0 144.1 139.3 102.7 142.9 102.7 213.5 226.9 214.1 98.4 98.6 95.6 140.0 100.0 106.5 99.6 96.8 97.8 93.7 99.6 104.1 207.3 205.1 284.9 0.0 61.7 0.0 0.0 0.0 0.0 0.0 251.1 314.3 0.0 0.0 150.4 546.2 0.0 453.8 165.4 0.0 1035.0 396.6 0.0 1524.2 210.6 84.0 0.0 0.0 0.0 672.1 226.0 114.6 0.0 453.2 172.8 1030.6 0.0 0.0 372.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 108.6 0.0 0.0 123.0 0.0 0.0 0.0 0.0 550.3 0.0 0.0 30.3 0.0 0.0 1502.7 621.6 0.0 0.0 0.0 90.6 0.0 0.0 0.0 0.0 251.7 92.0 281.6 0.0 0.0 BAD "BBC2, BCL2L8" ENSG00000002330 "BCL2 associated agonist of cell death" Q92934 11 64269830-64284704 "Cancer-related genes, Predicted intracellular proteins, RAS pathway related proteins" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004205, HPA028185, HPA062105" Approved Enhanced Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "CAB004205: AB_626717, HPA028185: AB_10603445, HPA062105: AB_2684684" "unprognostic (1.47e-1)" "unprognostic (3.08e-2)" "unprognostic (1.17e-1)" "unprognostic (8.24e-3)" "unprognostic (2.60e-1)" "unprognostic (6.73e-2)" "unprognostic (1.24e-3)" "unprognostic (1.07e-1)" "unprognostic (1.99e-1)" "unprognostic (1.10e-1)" "unprognostic (1.36e-1)" "unprognostic (1.14e-1)" "unprognostic (8.26e-2)" "unprognostic (9.04e-2)" "unprognostic (2.17e-1)" "unprognostic (1.48e-1)" "unprognostic (7.95e-2)" 60.8 85.1 94.0 13.2 91.1 23.3 58.8 89.0 133.1 64.9 86.6 81.7 26.5 64.8 12.7 72.9 58.8 15.5 118.0 93.1 87.8 87.6 96.1 58.7 14.7 93.4 92.7 55.2 53.7 35.6 55.3 21.7 89.4 79.7 15.1 17.2 57.7 27.6 50.7 70.6 44.7 14.0 89.9 45.0 87.1 55.1 98.9 17.2 75.8 15.1 12.4 65.9 57.7 92.7 95.0 85.1 25.2 38.3 30.0 36.4 36.9 38.2 45.9 60.0 47.5 54.8 53.1 19.5 67.7 37.4 46.9 49.9 16.8 62.7 11.9 77.6 58.7 24.9 81.4 26.1 45.9 20.7 45.0 35.3 53.7 45.8 28.3 45.9 37.5 44.1 10.1 42.9 26.6 94.7 49.8 49.7 9.8 27.7 109.6 46.7 13.8 57.9 36.8 44.3 51.2 67.1 39.2 46.8 49.9 9.6 70.5 32.0 30.3 72.8 48.1 112.8 43.8 79.6 64.0 21.3 59.2 15.6 40.6 88.0 69.7 102.3 52.9 56.7 54.7 58.6 55.4 51.9 50.5 57.5 39.8 40.9 92.4 59.5 55.3 94.0 71.8 51.4 94.0 91.1 89.0 133.1 93.1 87.8 93.4 92.7 89.4 89.9 98.9 92.7 56.3 32.1 45.1 7.8 32.9 103.1 54.1 170.2 51.2 67.7 76.7 74.8 51.6 70.1 66.4 53.3 18.8 162.5 32.4 214.4 137.0 101.2 43.5 71.5 64.8 56.8 104.1 69.2 10.4 109.9 197.8 75.3 53.0 45.4 24.1 58.2 62.4 51.0 73.8 47.1 7.5 141.8 89.5 24.1 72.6 93.3 74.3 32.9 110.3 2.8 52.4 95.9 36.0 4.0 8.9 120.7 210.0 85.4 33.2 62.1 138.1 152.8 83.2 52.0 59.2 36.2 72.6 69.5 25.0 57.7 119.1 255.0 36.0 57.8 117.1 63.4 BCL2L13 "BCL-RAMBO, MIL1" ENSG00000099968 "BCL2 like 13" Q9BXK5 22 17628855-17730855 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 59.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 180.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002052, HPA030994, HPA050377" Uncertain Enhanced Mitochondria NA NA 100000 "Cluster 7: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 56: Bipolar cells - Visual perception" Mitochondria "CAB002052: AB_563431, HPA030994: AB_10795024, HPA050377: AB_2681107" "unprognostic (1.59e-1)" "unprognostic (8.17e-2)" "unprognostic (2.18e-3)" "unprognostic (1.86e-1)" "unprognostic (6.27e-2)" "unprognostic (2.69e-2)" "unprognostic (3.38e-1)" "unprognostic (4.97e-2)" "unprognostic (5.04e-2)" "unprognostic (9.46e-2)" "unprognostic (1.45e-2)" "unprognostic (8.21e-2)" "prognostic favorable (1.96e-8)" "unprognostic (3.20e-1)" "unprognostic (1.07e-1)" "unprognostic (4.27e-1)" "unprognostic (2.81e-1)" 13.4 13.3 8.7 5.7 11.6 10.8 11.5 8.4 12.8 7.7 1.4 10.0 6.0 7.9 8.8 12.3 7.4 6.8 19.7 9.4 9.9 14.0 16.4 8.4 7.6 11.6 13.7 7.5 11.8 14.8 7.8 9.2 12.1 8.2 10.3 43.8 10.0 6.8 59.6 14.1 7.8 7.6 9.2 6.4 9.5 10.7 9.7 9.2 9.6 40.5 8.7 10.3 8.7 9.4 16.2 6.1 10.6 11.1 19.6 18.8 17.2 11.4 21.3 17.1 19.8 8.3 11.7 14.6 7.5 15.4 13.9 21.3 12.6 18.4 20.9 12.2 12.3 14.5 7.5 6.1 22.3 21.3 10.0 14.5 21.1 14.0 40.1 24.2 14.7 11.3 34.5 15.2 18.9 11.6 11.7 8.9 10.7 26.8 9.7 10.9 20.7 5.3 20.1 12.4 15.6 11.5 16.4 15.6 31.0 38.0 11.9 18.0 17.2 9.9 5.0 15.3 10.5 11.9 10.5 14.7 14.9 16.1 16.4 5.1 9.5 2.3 2.3 8.0 2.8 3.1 3.1 2.7 5.4 3.2 2.8 2.3 3.6 6.5 6.4 2.9 4.5 4.7 8.7 11.6 8.4 12.8 9.4 9.9 11.6 13.7 12.1 9.2 9.7 9.4 18.7 22.4 16.7 32.3 21.5 24.6 33.6 22.7 30.1 180.5 21.8 22.4 42.7 12.8 25.3 18.4 12.5 48.5 19.7 31.7 52.8 29.1 34.8 17.7 16.0 17.5 23.4 19.8 41.9 31.6 35.0 20.0 13.3 23.5 8.8 19.7 15.7 36.0 26.0 48.8 38.1 25.4 18.3 30.8 19.8 15.5 14.0 26.3 16.0 27.2 54.7 57.9 12.3 27.6 45.4 36.4 17.8 15.4 15.4 40.3 32.6 44.4 19.6 35.2 0.0 21.3 15.6 33.1 22.6 32.1 27.1 95.9 19.3 22.9 24.0 43.1 BNIP3L "BNIP3a, Nix" ENSG00000104765 "BCL2 interacting protein 3 like" O60238 8 26383054-26505636 "Cancer-related genes, Predicted membrane proteins, Transporters" "Apoptosis, Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 913.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015652, CAB025371" Enhanced Supported "Nuclear speckles,Mitochondria" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 6: Erythroid cells - Oxygen transport" Mitochondria "Nuclear speckles" "CAB025371: , HPA015652: AB_1845406" "unprognostic (1.02e-1)" "unprognostic (2.90e-1)" "unprognostic (2.00e-1)" "unprognostic (8.36e-2)" "unprognostic (6.24e-2)" "unprognostic (1.63e-1)" "unprognostic (1.64e-3)" "unprognostic (1.46e-2)" "unprognostic (5.04e-2)" "unprognostic (2.02e-1)" "unprognostic (2.06e-2)" "unprognostic (2.97e-2)" "prognostic unfavorable (5.92e-5)" "unprognostic (8.72e-3)" "unprognostic (5.16e-2)" "prognostic unfavorable (3.95e-4)" "unprognostic (7.59e-3)" 130.6 53.4 42.7 37.2 60.4 192.6 77.9 55.6 62.0 63.9 38.9 39.6 22.2 52.8 66.3 48.3 50.5 54.7 63.2 50.0 49.6 79.4 45.4 62.9 39.4 60.7 54.0 119.7 20.1 55.1 25.4 104.5 58.4 44.4 28.2 146.5 44.1 64.4 38.9 71.5 28.4 51.3 46.6 40.7 28.9 68.6 48.8 39.9 41.9 31.7 52.1 48.9 49.5 80.8 90.6 33.8 79.1 53.9 214.5 134.0 66.8 89.0 259.9 81.9 179.6 15.3 42.7 27.7 82.5 169.0 113.4 44.8 39.6 114.5 270.0 17.8 21.8 114.9 32.0 26.9 119.3 10.3 191.1 162.5 89.2 92.9 55.3 269.2 106.2 66.9 52.6 65.0 173.7 39.1 72.7 38.5 26.2 56.7 36.6 38.4 99.9 55.6 85.3 58.3 83.9 74.4 43.2 8.8 70.0 85.9 43.7 21.7 140.4 152.2 64.6 96.2 20.5 93.2 46.0 36.8 232.6 20.6 35.1 334.9 298.3 182.9 39.5 154.8 34.9 68.4 58.4 43.3 166.9 78.0 89.3 65.5 369.0 47.6 104.1 38.0 86.1 239.3 42.7 60.4 55.6 62.0 50.0 49.6 60.7 54.0 58.4 46.6 48.8 80.8 118.3 86.6 157.4 28.7 72.2 98.8 56.0 231.7 82.6 142.5 90.6 85.3 34.0 50.1 126.4 103.0 33.3 33.2 55.6 32.7 49.0 115.4 194.1 173.5 140.8 101.2 120.6 913.9 50.6 39.1 166.5 179.9 38.7 341.2 120.9 96.5 167.0 32.2 132.1 82.4 39.4 46.8 118.0 221.3 300.4 206.7 320.3 233.6 106.7 30.0 165.0 406.4 32.0 29.1 75.8 154.1 39.8 347.5 64.6 83.6 44.0 306.4 107.6 64.0 144.7 59.1 183.9 154.4 110.7 65.4 126.6 162.5 67.0 117.6 27.6 79.3 CCDC90B "MDS011, MDS025" ENSG00000137500 "Coiled-coil domain containing 90B" Q9GZT6 11 83259097-83286407 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 447.3;Late spermatids: 233.9;Spermatocytes: 333.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011130, HPA011931" Supported Enhanced Mitochondria NA NA "Cluster 10: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 34: Spermatids - Unknown function" Mitochondria "HPA011130: AB_1846170, HPA011931: AB_2072332" "unprognostic (5.85e-2)" "unprognostic (1.33e-1)" "unprognostic (7.34e-2)" "unprognostic (9.71e-2)" "unprognostic (1.34e-1)" "unprognostic (7.48e-2)" "unprognostic (2.99e-1)" "unprognostic (3.57e-3)" "unprognostic (5.76e-3)" "unprognostic (3.53e-2)" "unprognostic (6.01e-3)" "unprognostic (2.01e-2)" "unprognostic (1.00e-2)" "unprognostic (2.31e-1)" "unprognostic (3.03e-1)" "unprognostic (1.62e-1)" "unprognostic (2.41e-1)" 16.4 37.3 23.2 13.0 24.5 16.1 21.3 24.2 29.8 17.1 23.3 18.1 14.7 14.7 33.8 16.2 15.6 18.2 22.1 22.9 25.4 18.4 38.9 13.5 20.5 25.3 25.0 22.3 18.3 14.9 19.4 22.2 25.0 16.0 17.3 12.6 17.1 16.3 16.2 14.1 16.6 16.7 25.2 15.5 16.9 54.5 24.4 17.2 25.6 17.7 17.0 15.3 14.2 27.1 19.1 27.3 46.1 15.2 59.6 44.7 27.7 37.4 31.6 22.7 24.3 32.2 63.0 46.7 47.7 55.0 47.5 23.5 20.1 47.3 30.3 31.9 16.0 28.2 17.7 27.3 50.1 29.2 23.5 50.2 62.3 29.5 83.8 45.3 52.3 49.6 41.9 37.9 83.7 33.5 29.4 36.7 37.9 80.2 33.4 33.1 40.9 39.3 47.3 27.5 22.2 50.9 26.4 21.0 26.1 60.8 53.9 26.4 51.6 44.8 28.8 85.9 26.0 36.3 51.2 46.8 18.1 23.2 45.5 77.7 18.7 71.6 24.2 41.3 31.2 39.8 34.7 34.2 27.0 37.9 30.2 30.2 9.8 50.7 43.8 20.4 46.0 27.4 23.2 24.5 24.2 29.8 22.9 25.4 25.3 25.0 25.0 25.2 24.4 27.1 50.8 12.8 13.1 14.0 40.5 23.6 49.6 102.8 26.7 36.3 33.5 49.7 58.0 28.6 48.3 36.8 14.6 74.0 41.4 21.0 68.4 59.4 447.3 39.5 38.0 45.8 33.6 36.2 16.0 48.5 55.4 44.5 26.5 31.4 49.4 83.0 35.7 43.3 63.7 42.1 23.3 35.2 52.9 34.6 32.4 233.9 42.6 38.6 21.4 10.3 52.8 35.3 53.5 31.2 48.2 67.6 32.9 25.6 44.6 38.9 44.1 78.0 32.6 50.0 26.3 40.3 43.5 333.0 107.8 32.5 29.0 51.7 37.1 86.8 31.2 49.9 CCM2 "C7orf22, MGC4607, OSM" ENSG00000136280 "CCM2 scaffold protein" Q9BSQ5 7 44999475-45076469 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 140.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020273, HPA021669, HPA065815" Supported Enhanced Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 3: Monocytes - Immune response regulation" Mitochondria "HPA020273: AB_1846185, HPA021669: AB_1846186, HPA065815: AB_2685562" "unprognostic (4.30e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (1.79e-4)" "unprognostic (3.17e-1)" "prognostic unfavorable (2.45e-4)" "unprognostic (4.85e-2)" "unprognostic (1.55e-2)" "unprognostic (7.37e-3)" "unprognostic (3.92e-1)" "unprognostic (2.65e-1)" "prognostic favorable (1.16e-4)" "unprognostic (3.03e-1)" "prognostic unfavorable (5.06e-7)" "unprognostic (2.45e-1)" "unprognostic (1.79e-1)" "unprognostic (2.81e-2)" "unprognostic (2.48e-1)" 32.7 40.7 62.5 25.1 74.5 15.5 26.6 58.7 89.1 19.1 48.4 30.2 13.2 20.3 6.4 22.4 18.9 11.5 37.1 63.0 62.4 24.2 86.0 29.2 43.6 67.6 62.8 16.1 26.6 21.4 30.4 14.5 69.2 23.8 10.8 9.4 18.8 14.5 48.2 21.1 27.6 16.9 60.0 54.6 24.0 30.3 71.5 45.4 18.7 36.9 29.6 27.2 20.0 68.6 38.7 41.8 24.4 49.2 45.5 39.8 17.7 45.9 37.3 32.0 43.3 30.6 39.3 53.7 34.5 58.5 101.8 49.5 15.3 58.9 21.4 61.0 29.7 23.3 34.0 22.1 39.9 9.9 61.5 44.7 38.0 56.3 24.0 30.0 59.2 76.8 27.5 42.1 64.7 58.2 47.9 131.6 28.4 32.3 46.1 25.7 14.2 43.9 33.1 36.8 46.9 36.8 37.5 29.2 20.9 31.7 33.3 45.7 45.1 43.4 36.4 44.2 44.8 75.9 64.0 109.2 42.3 35.7 53.4 108.1 33.5 105.8 52.2 40.2 35.2 42.0 62.3 57.4 23.6 43.6 58.9 44.1 103.9 60.9 47.7 23.8 167.1 40.2 62.5 74.5 58.7 89.1 63.0 62.4 67.6 62.8 69.2 60.0 71.5 68.6 28.7 19.2 19.4 26.1 57.5 46.8 22.6 27.6 54.7 19.0 13.5 24.6 13.0 20.0 18.8 14.7 4.2 28.3 53.7 30.5 25.4 30.2 6.9 6.0 14.3 26.7 15.6 13.7 33.3 38.5 35.8 25.0 11.2 7.4 36.1 23.8 30.4 56.5 49.3 82.4 24.9 15.2 12.2 47.9 51.1 12.8 21.1 47.7 33.8 56.2 140.0 34.1 122.6 20.1 51.7 45.3 11.4 20.3 69.1 40.4 13.6 22.9 8.0 14.4 19.7 16.2 29.6 15.3 37.8 16.8 23.0 10.4 55.7 36.9 15.2 19.7 CCR7 "BLR2, CD197, CDw197, CMKBR7, EBI1" ENSG00000126353 "C-C motif chemokine receptor 7" P32248 17 40553769-40565472 "Cancer-related genes, CD markers, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 21.3;lymphoid tissue: 84.0" "Group enriched" "Detected in many" 4 "Langerhans cells: 415.0;monocytes: 1586.1;Syncytiotrophoblasts: 517.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in all" "naive CD4 T-cell: 4597.2" "Lineage enriched" "Detected in all" 4 "T-cells: 4597.2" "Cell line enriched" "Detected in some" 82 "HDLM-2: 1386.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB003796, HPA031383, HPA074467" Enhanced Enhanced Mitochondria NA NA "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" Mitochondria "CAB003796: AB_562261, HPA031383: AB_2673854, HPA074467: AB_2686693" "prognostic favorable (3.84e-4)" "prognostic favorable (8.03e-6)" "unprognostic (2.26e-3)" "unprognostic (1.32e-3)" "unprognostic (2.35e-3)" "prognostic favorable (7.61e-7)" "unprognostic (2.71e-4)" "unprognostic (2.58e-2)" "unprognostic (4.48e-2)" "unprognostic (4.68e-4)" "unprognostic (1.10e-2)" "unprognostic (3.11e-1)" "unprognostic (1.08e-3)" "unprognostic (3.12e-1)" "prognostic unfavorable (7.72e-4)" "unprognostic (1.02e-1)" "unprognostic (7.95e-2)" 4.6 0.6 0.0 67.2 0.3 15.2 2.3 0.0 0.2 2.7 0.6 3.6 1.2 1.6 0.0 2.0 3.9 5.1 2.5 0.1 0.0 2.1 2.3 2.7 84.0 0.2 0.1 1.8 0.6 0.1 1.4 1.1 0.2 1.9 5.1 0.5 1.8 0.3 0.5 2.2 21.3 0.9 0.0 28.6 5.3 1.9 0.2 58.8 2.8 0.4 83.3 8.8 2.0 0.8 0.4 1.5 0.0 0.0 0.0 0.3 16.8 0.4 0.1 0.0 0.0 0.2 0.0 0.6 0.9 0.0 0.1 0.2 0.0 0.0 0.0 1386.6 0.1 0.0 0.2 0.5 0.0 3.9 0.0 0.5 0.0 0.0 0.0 1.9 0.0 0.3 0.8 0.2 0.0 0.4 1.2 3.0 0.1 0.0 0.0 4.5 0.9 0.0 0.0 0.6 0.0 0.0 0.0 0.6 0.2 1.0 0.6 1.6 0.0 0.4 0.1 1.6 0.7 7.5 0.9 9.0 1.9 0.1 0.0 25.6 6.5 4.2 61.1 3.5 69.2 794.6 996.2 285.4 4.2 1122.5 4597.2 2462.0 45.3 970.9 6.4 58.5 637.3 2489.9 0.0 0.3 0.0 0.2 0.1 0.0 0.2 0.1 0.2 0.0 0.2 0.8 1.2 0.0 3.7 0.0 201.4 5.0 1.5 0.0 0.0 0.0 0.7 0.4 0.3 0.0 1.3 1.8 0.0 143.8 9.5 0.0 0.0 0.6 0.3 0.5 0.3 1.0 0.0 0.4 0.0 8.3 24.2 1.6 1.1 0.4 2.5 0.0 0.4 0.0 12.8 0.0 0.0 0.0 0.0 0.0 415.0 0.2 0.0 75.7 16.0 0.0 1586.1 0.4 3.1 0.0 0.1 0.5 0.0 0.0 3.6 0.2 0.0 0.3 0.0 0.0 0.0 0.2 2.4 0.6 0.8 0.0 4.4 517.6 75.2 0.1 0.0 4.6 COA3 "CCDC56, COX25, HSPC009, MITRAC12" ENSG00000183978 "Cytochrome c oxidase assembly factor 3" Q9Y2R0 17 42795147-42798704 "Disease related genes, Predicted membrane proteins" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 710.2;Proximal tubular cells: 729.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031966, HPA071122" Approved Enhanced Mitochondria NA NA 13000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 22: Non-specific - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA031966: AB_10602115, HPA071122: " "unprognostic (1.20e-1)" "prognostic favorable (3.40e-4)" "unprognostic (5.65e-2)" "prognostic favorable (8.93e-4)" "unprognostic (7.62e-2)" "unprognostic (2.19e-1)" "unprognostic (4.78e-2)" "unprognostic (1.16e-2)" "unprognostic (1.48e-1)" "unprognostic (2.25e-2)" "unprognostic (8.44e-3)" "unprognostic (1.52e-1)" "prognostic favorable (6.62e-4)" "unprognostic (1.64e-1)" "unprognostic (2.70e-1)" "unprognostic (3.16e-2)" "unprognostic (3.01e-2)" 64.8 73.0 122.8 30.8 122.9 15.3 63.7 128.2 160.5 71.5 125.8 110.8 106.0 55.6 172.3 128.4 73.7 42.9 102.4 125.6 124.5 223.4 158.9 45.7 41.0 124.6 125.4 55.8 172.6 106.8 59.7 38.9 127.2 84.9 89.7 34.9 66.1 66.7 119.6 58.0 81.1 41.5 125.8 50.5 128.5 25.2 125.5 42.7 57.9 94.3 49.8 60.5 78.6 125.3 66.8 219.9 99.4 54.7 89.5 75.8 61.0 51.1 77.2 119.2 107.3 87.5 81.8 3.9 141.0 62.5 112.4 63.5 77.3 124.8 111.9 65.1 202.8 44.7 96.3 280.8 63.4 61.0 52.0 77.4 92.0 112.7 64.2 61.0 96.1 31.6 72.9 55.5 106.9 108.9 20.2 132.9 45.7 135.9 78.5 79.4 145.1 113.6 122.6 90.2 73.8 61.9 52.2 54.9 91.5 85.3 170.3 78.5 59.3 129.6 67.5 55.4 69.0 65.1 76.3 36.2 97.3 60.1 89.8 206.7 209.6 141.5 136.2 208.1 143.5 218.9 140.0 138.3 178.8 187.5 128.4 126.2 22.7 187.5 177.7 120.3 191.1 245.9 122.8 122.9 128.2 160.5 125.6 124.5 124.6 125.4 127.2 125.8 125.5 125.3 55.4 28.9 68.7 7.5 44.5 36.8 52.2 192.7 50.7 36.5 99.9 110.9 263.9 173.0 113.8 266.7 20.9 153.9 30.3 233.8 710.2 136.5 13.2 203.0 70.0 65.4 79.9 54.3 8.1 239.8 177.5 72.5 103.5 154.6 35.5 77.5 69.3 390.1 121.6 45.4 9.2 205.9 195.3 75.3 33.4 18.8 55.9 54.8 88.9 6.5 86.0 94.7 63.8 6.6 11.8 134.7 201.6 45.1 73.2 79.0 221.7 729.1 145.2 37.0 39.5 46.2 88.0 48.4 52.1 242.0 55.5 102.2 43.4 97.6 258.9 67.7 COQ8B "ADCK4, COQ8, FLJ12229" ENSG00000123815 "Coenzyme Q8B" Q96D53 19 40691514-40725784 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 16.5;Endometrial ciliated cells: 16.4;Theca cells: 19.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027229, HPA027277, HPA027279, HPA028303" Supported Enhanced Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 6: T47d - Mammary gland" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA027229: AB_10600100, HPA027277: AB_10599857, HPA027279: AB_10601219, HPA028303: AB_2672551" "unprognostic (7.57e-2)" "unprognostic (9.48e-2)" "unprognostic (1.61e-1)" "unprognostic (2.36e-2)" "unprognostic (2.33e-2)" "unprognostic (1.19e-1)" "unprognostic (1.79e-1)" "unprognostic (4.63e-2)" "unprognostic (1.85e-1)" "unprognostic (2.27e-1)" "unprognostic (2.82e-2)" "unprognostic (1.48e-1)" "unprognostic (2.93e-2)" "unprognostic (6.18e-2)" "unprognostic (1.46e-1)" "unprognostic (7.17e-2)" "unprognostic (2.65e-2)" 15.1 25.2 10.1 5.7 10.7 5.9 15.3 10.4 12.8 23.4 10.9 19.4 9.7 22.0 2.3 16.0 29.8 7.6 21.9 9.8 10.6 21.0 25.7 16.4 6.0 10.6 10.8 22.5 20.7 8.4 49.3 3.5 10.3 23.2 2.3 1.3 16.9 7.3 14.4 20.2 17.8 3.8 11.2 18.3 23.9 17.3 10.6 8.8 23.3 8.6 3.3 20.3 18.4 10.5 9.9 39.5 7.9 18.5 7.8 6.1 8.5 6.6 7.8 5.6 5.1 15.4 14.3 13.8 20.0 4.3 7.8 9.8 7.0 10.5 2.0 20.0 10.4 11.6 12.7 6.4 12.1 4.1 19.2 8.4 10.6 5.4 5.4 5.2 7.4 13.7 7.7 8.1 6.0 6.4 4.9 5.7 6.4 11.5 3.6 11.5 13.1 12.4 15.7 17.6 15.1 11.0 12.5 20.4 21.0 4.4 22.8 17.1 9.4 5.1 20.6 3.9 5.5 9.4 9.0 7.3 27.8 5.2 9.1 10.2 9.4 8.7 6.7 9.3 8.3 7.1 5.5 7.8 9.9 5.9 4.6 5.1 9.0 6.9 9.2 4.6 4.9 7.3 10.1 10.7 10.4 12.8 9.8 10.6 10.6 10.8 10.3 11.2 10.6 10.5 8.5 12.8 3.9 0.0 1.2 0.0 0.0 0.0 0.0 0.0 11.6 8.0 0.0 0.0 2.5 12.9 0.0 11.1 6.8 0.0 11.7 16.5 0.0 16.4 7.8 1.7 0.0 0.0 0.0 10.9 9.8 5.0 0.0 10.3 1.3 11.7 0.0 0.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 9.5 0.0 0.0 1.2 0.0 0.0 13.0 8.7 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 9.4 3.2 19.8 0.0 0.0 COX20 "FAM36A, FLJ43269" ENSG00000203667 "Cytochrome c oxidase assembly factor COX20" Q5RI15 1 244835616-244845057 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 414.8;Proximal tubular cells: 464.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043617, HPA045490" Approved Enhanced Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA043617: AB_10965694, HPA045490: AB_10962869" "unprognostic (5.84e-3)" "unprognostic (1.20e-1)" "unprognostic (7.33e-2)" "unprognostic (2.86e-1)" "unprognostic (3.62e-1)" "unprognostic (3.70e-2)" "unprognostic (1.07e-1)" "unprognostic (1.62e-1)" "unprognostic (1.03e-1)" "prognostic favorable (3.13e-4)" "unprognostic (1.99e-1)" "unprognostic (6.38e-2)" "unprognostic (3.44e-2)" "unprognostic (2.54e-2)" "unprognostic (3.70e-2)" "unprognostic (3.10e-1)" "unprognostic (7.02e-3)" 17.5 44.2 28.1 23.3 30.9 20.1 22.1 37.4 49.2 13.9 23.6 23.9 24.3 24.8 29.9 21.5 17.2 15.3 42.9 27.9 30.1 50.2 29.6 15.8 21.4 30.3 30.3 35.4 23.2 22.8 11.1 17.7 28.8 28.7 18.7 58.3 17.1 18.6 43.3 15.2 25.0 20.5 29.2 15.0 23.1 25.0 29.3 16.3 37.0 37.4 16.5 20.4 9.6 30.1 132.6 34.1 33.5 100.4 22.5 17.3 75.2 54.0 35.7 31.0 27.2 93.9 88.9 21.3 65.7 36.6 58.3 36.1 17.8 43.0 40.8 56.0 15.6 38.6 47.6 85.7 28.7 95.7 57.5 16.0 20.2 44.5 30.8 44.9 35.2 22.7 81.2 80.2 63.0 33.0 53.5 43.5 84.2 94.9 68.6 38.5 42.0 121.5 59.5 33.1 19.6 54.2 68.1 36.1 79.6 32.1 67.0 28.7 69.3 67.3 88.7 59.9 120.1 128.0 188.7 43.7 90.9 108.2 65.3 14.5 15.3 21.4 27.1 36.4 26.3 34.2 31.3 30.2 26.5 32.6 21.2 28.7 3.9 24.2 34.5 26.1 43.4 20.4 28.1 30.9 37.4 49.2 27.9 30.1 30.3 30.3 28.8 29.2 29.3 30.1 66.7 19.2 52.1 44.1 77.7 85.1 115.1 144.3 38.1 111.5 104.4 110.1 68.6 183.0 90.5 191.3 45.9 231.5 74.4 97.7 414.8 154.1 38.6 78.4 74.1 61.4 61.8 82.0 16.6 188.9 164.6 56.1 57.6 119.5 73.4 53.1 42.5 294.8 122.1 89.2 24.4 91.7 77.3 64.8 79.6 75.9 69.6 73.4 72.9 9.4 97.6 195.2 110.2 27.6 34.1 178.6 87.0 80.1 51.9 75.9 134.8 464.0 67.7 133.4 65.7 83.2 85.0 67.1 122.4 61.6 75.6 264.5 81.4 63.6 115.3 87.8 COX5B ENSG00000135940 "Cytochrome c oxidase subunit 5B" P10606 2 97646062-97648383 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1151.3;skeletal muscle: 1332.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 3614.3;Distal tubular cells: 3621.5;Proximal enterocytes: 2795.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034517 Supported Enhanced Mitochondria NA NA 230000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA034517: AB_10603561" "unprognostic (4.61e-2)" "unprognostic (4.33e-2)" "unprognostic (1.71e-1)" "unprognostic (1.26e-1)" "unprognostic (1.39e-1)" "unprognostic (1.92e-2)" "unprognostic (2.48e-1)" "unprognostic (1.01e-1)" "unprognostic (1.86e-1)" "unprognostic (2.72e-2)" "unprognostic (1.79e-2)" "unprognostic (4.20e-2)" "unprognostic (4.02e-2)" "unprognostic (3.32e-1)" "unprognostic (1.01e-1)" "unprognostic (1.34e-1)" "prognostic favorable (2.73e-4)" 209.1 252.9 323.0 42.8 339.7 113.3 178.7 373.1 436.0 138.1 349.2 322.6 164.2 124.6 72.3 284.6 136.9 32.6 1151.3 319.2 357.2 478.6 372.8 120.4 40.3 341.7 339.9 138.4 165.6 234.0 169.0 47.1 339.9 158.2 113.4 74.5 196.7 90.1 1332.7 213.2 211.9 51.1 332.9 153.2 290.6 101.2 353.1 64.4 185.0 705.9 54.3 179.8 179.1 355.3 144.9 165.5 106.8 169.7 115.9 105.8 428.3 180.0 100.8 118.3 130.5 459.9 148.7 240.8 377.3 116.5 188.4 217.9 117.5 181.8 56.4 188.7 493.2 324.2 166.6 559.8 220.3 310.6 231.2 193.8 161.6 113.4 91.2 125.4 104.4 187.8 243.6 115.5 94.0 360.0 203.5 450.0 196.6 257.2 854.3 194.9 170.6 368.8 167.5 227.9 202.2 210.3 175.0 225.0 374.8 146.0 115.7 345.5 186.9 107.5 181.4 174.4 118.7 265.8 274.7 183.1 194.9 264.5 113.5 1086.6 1062.7 933.1 458.0 1057.0 445.1 801.5 547.4 481.8 990.1 666.0 528.0 468.8 1016.6 469.6 926.3 677.6 783.4 1543.0 323.0 339.7 373.1 436.0 319.2 357.2 341.7 339.9 339.9 332.9 353.1 355.3 461.0 221.2 256.0 33.3 292.7 386.6 629.5 1166.0 377.9 239.1 433.2 536.2 3614.3 567.6 618.5 800.0 227.2 736.0 257.4 1960.0 3621.5 599.5 207.5 399.4 300.8 380.0 740.3 308.8 27.3 604.1 897.1 391.6 616.7 439.7 330.6 392.2 361.3 1234.9 875.0 141.3 33.7 1430.5 1043.6 485.2 651.9 360.8 351.6 456.6 912.4 30.0 711.7 461.5 314.1 15.6 39.4 505.4 1836.0 304.6 353.3 468.2 2795.9 2663.5 485.4 386.3 447.0 340.2 569.9 265.2 310.7 944.2 479.9 613.2 291.9 455.7 1576.9 915.9 COX7A2L "COX7AR, COX7RP, EB1, SIG81" ENSG00000115944 "Cytochrome c oxidase subunit 7A2 like" O14548 2 42333546-42425088 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059124, CAB073545" Enhanced Nucleoli,Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 18: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoli "CAB073545: , HPA059124: AB_2683912" "unprognostic (3.90e-1)" "unprognostic (1.02e-1)" "unprognostic (1.18e-1)" "unprognostic (5.45e-2)" "unprognostic (4.60e-2)" "unprognostic (1.27e-2)" "prognostic unfavorable (4.13e-5)" "unprognostic (1.17e-1)" "unprognostic (3.12e-1)" "unprognostic (1.66e-2)" "unprognostic (2.43e-1)" "unprognostic (7.07e-3)" "unprognostic (1.54e-2)" "unprognostic (2.76e-1)" "unprognostic (5.53e-2)" "unprognostic (6.19e-2)" "unprognostic (1.02e-1)" 79.5 222.7 53.9 18.7 57.5 56.9 78.3 53.1 62.5 93.0 56.1 84.0 32.5 74.8 42.8 60.8 81.0 22.7 102.6 56.2 56.9 130.2 113.9 64.0 32.3 54.8 53.2 127.6 89.8 71.8 128.0 22.8 55.9 71.6 39.2 62.4 67.2 32.4 83.3 72.1 66.0 28.0 53.0 65.9 99.9 54.5 54.8 42.0 56.6 39.3 35.0 74.2 70.4 53.4 72.1 50.7 49.0 54.0 92.4 121.8 55.8 58.2 85.8 51.5 66.0 56.9 48.9 63.1 54.8 71.9 70.0 30.3 65.5 65.9 80.1 99.5 47.5 46.0 31.9 95.5 106.2 66.5 42.5 123.7 128.6 55.5 132.6 78.5 77.4 49.7 64.1 101.1 83.9 68.6 75.3 96.8 45.3 91.6 48.1 40.7 87.5 51.6 84.6 57.4 55.8 63.7 25.7 60.4 166.1 58.2 43.2 73.3 60.1 45.4 61.2 55.3 57.1 84.1 98.7 46.0 63.1 68.8 39.9 103.7 78.6 43.2 57.9 71.1 75.6 72.6 70.4 67.1 84.4 61.9 77.8 67.0 34.1 69.1 80.1 99.0 87.3 189.3 53.9 57.5 53.1 62.5 56.2 56.9 54.8 53.2 55.9 53.0 54.8 53.4 150.7 32.1 76.3 11.4 152.5 265.6 197.9 387.2 135.5 114.8 206.8 237.6 158.7 171.6 173.4 149.0 37.5 228.1 163.4 103.8 645.6 239.1 27.4 189.5 133.3 144.0 288.7 188.7 28.2 229.5 316.2 128.5 123.8 175.9 87.0 155.8 132.1 222.3 234.0 131.2 26.1 285.8 282.8 236.3 225.1 26.3 161.8 161.6 220.5 19.7 298.4 326.8 166.9 13.6 24.5 202.1 173.0 158.7 167.7 214.2 247.1 492.4 160.9 123.6 111.7 137.6 175.2 220.4 270.8 162.7 245.5 329.6 161.8 296.2 257.0 241.7 CS ENSG00000062485 "Citrate synthase" O75390 12 56271699-56300391 "Citric acid cycle related proteins, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Tricarboxylic acid cycle" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 550.1;tongue: 600.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 239.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038460, HPA038461, CAB075750, CAB075751, CAB075752, CAB075753, CAB075754" Enhanced Enhanced Mitochondria NA NA 670000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "CAB075750: AB_2665756, CAB075751: AB_2665757, CAB075752: AB_2665758, CAB075753: AB_2665759, CAB075754: AB_2665760, HPA038460: AB_2676023, HPA038461: AB_2676024" "unprognostic (7.67e-3)" "unprognostic (3.80e-1)" "unprognostic (2.59e-2)" "unprognostic (2.50e-2)" "unprognostic (2.70e-2)" "unprognostic (1.25e-1)" "unprognostic (6.09e-3)" "unprognostic (3.34e-2)" "unprognostic (2.43e-1)" "unprognostic (5.58e-2)" "unprognostic (2.56e-1)" "unprognostic (1.97e-2)" "prognostic favorable (1.17e-4)" "unprognostic (1.20e-1)" "unprognostic (2.09e-1)" "unprognostic (1.30e-2)" "unprognostic (2.02e-1)" 154.2 93.6 29.2 61.7 30.0 111.0 66.3 33.7 49.9 55.4 40.5 110.1 97.7 56.4 32.2 95.6 58.3 42.4 319.3 30.9 34.6 86.6 39.0 58.0 67.2 39.4 32.0 56.0 61.5 127.6 28.9 45.7 39.4 59.0 124.1 128.9 73.7 60.5 550.1 70.5 81.2 77.5 22.5 49.0 66.5 24.4 41.0 69.4 53.0 600.7 106.1 70.2 58.2 31.6 168.9 176.8 141.6 198.2 188.4 173.8 93.3 136.9 132.0 231.1 160.6 271.2 158.2 322.9 128.2 172.6 99.3 182.1 396.8 200.8 234.9 109.3 200.2 222.9 136.1 261.4 107.3 288.4 166.6 188.2 201.6 182.4 232.0 202.2 268.6 163.7 233.2 193.7 214.7 160.8 229.8 121.9 117.5 128.0 247.8 222.3 167.1 247.6 166.2 194.6 189.3 125.2 175.2 251.7 157.7 137.5 297.6 174.3 178.3 127.1 165.3 167.4 147.4 124.5 200.4 206.2 120.4 206.4 119.5 59.6 73.3 205.7 47.0 93.0 61.9 60.6 56.5 45.1 119.3 51.8 59.2 47.9 31.3 51.6 94.0 65.6 63.4 71.2 29.2 30.0 33.7 49.9 30.9 34.6 39.4 32.0 39.4 22.5 41.0 31.6 14.5 16.0 39.5 32.3 31.6 39.0 23.5 26.9 46.7 22.8 38.3 29.7 239.9 15.7 21.5 12.9 62.6 18.5 24.1 66.9 35.2 32.5 6.6 25.1 31.5 27.2 16.9 36.0 21.5 45.1 31.3 25.8 42.3 53.5 27.9 21.3 18.9 29.7 34.3 10.1 24.6 43.9 20.3 39.4 35.0 4.8 20.2 34.6 10.6 9.4 44.8 16.7 16.5 18.6 18.8 44.6 35.7 19.9 46.7 33.1 50.4 22.0 14.9 38.3 13.1 27.8 38.2 29.7 25.8 74.8 52.1 16.8 25.8 32.0 71.3 34.5 CYCS "CYC, HCS" ENSG00000172115 "Cytochrome c, somatic" P99999 7 25118656-25125260 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Electron transport, Respiratory chain, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 799.8" "Cell type enhanced" "Detected in all" "Distal tubular cells: 1663.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004222, CAB005126, CAB018597" Enhanced Supported Mitochondria NA NA 170000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria "CAB004222: AB_627385, CAB005126: AB_2090472, CAB018597: AB_627383" "unprognostic (3.06e-2)" "unprognostic (3.39e-1)" "unprognostic (3.32e-2)" "unprognostic (4.11e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (2.81e-4)" "unprognostic (4.44e-2)" "unprognostic (7.04e-3)" "unprognostic (5.67e-2)" "unprognostic (6.22e-2)" "unprognostic (2.41e-1)" "unprognostic (1.52e-1)" "prognostic favorable (1.30e-5)" "unprognostic (1.18e-1)" "unprognostic (4.94e-2)" "unprognostic (8.75e-3)" "unprognostic (7.04e-2)" 86.0 115.6 65.8 89.2 70.4 85.0 59.2 79.8 101.7 45.3 87.6 263.6 150.1 42.3 41.5 105.9 43.0 52.9 476.8 72.1 82.8 174.6 115.7 54.3 63.8 71.0 72.9 48.1 38.5 226.2 57.0 43.0 69.4 54.3 238.8 153.9 58.0 60.1 483.7 47.6 120.1 91.1 70.2 48.0 108.1 61.1 83.4 74.0 74.6 799.8 89.4 119.8 60.1 71.7 336.4 185.1 195.0 273.7 108.7 83.1 199.6 314.4 128.0 229.2 264.5 307.4 222.2 383.8 152.9 138.5 678.3 385.8 396.5 295.0 401.2 115.0 179.1 318.6 208.9 218.7 170.2 739.0 271.1 111.2 257.5 230.9 492.9 99.4 209.5 232.2 597.1 397.9 246.0 155.1 408.6 284.4 365.1 746.3 343.0 282.1 235.3 364.5 360.9 322.5 392.6 190.3 164.5 689.0 267.9 338.7 359.5 436.6 152.8 209.3 383.3 329.8 591.8 401.4 507.3 860.5 281.0 526.4 606.7 65.3 56.2 42.8 68.0 106.0 82.5 102.5 62.2 71.6 105.7 90.0 58.6 70.2 8.2 73.3 96.8 81.5 87.5 83.0 65.8 70.4 79.8 101.7 72.1 82.8 71.0 72.9 69.4 70.2 83.4 71.7 244.3 83.3 118.6 42.4 337.6 689.8 818.3 698.5 237.9 163.1 210.6 179.6 770.0 144.4 314.2 183.9 77.2 192.6 304.4 827.5 1663.0 278.3 496.4 154.8 120.2 183.3 384.9 162.6 53.2 216.0 351.0 257.3 287.5 197.5 212.6 68.7 81.0 210.8 353.0 132.9 64.6 522.5 502.5 141.5 715.2 161.8 90.1 329.2 590.5 16.9 245.8 220.9 197.8 17.1 24.2 303.8 570.5 93.6 358.7 551.9 392.8 638.6 146.1 195.2 138.1 294.7 962.3 423.1 211.1 402.7 715.2 349.3 349.7 146.9 600.2 884.1 DAP3 "bMRP-10, DAP-3, DKFZp686G12159, MGC126058, MGC126059, MRP-S29, MRPS29" ENSG00000132676 "Death associated protein 3" P51398 1 155687960-155739010 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" Apoptosis "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023687 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 32: Non-specific - Translation" "Nucleoplasm, Mitochondria" "HPA023687: AB_1847472" "unprognostic (2.60e-1)" "unprognostic (2.13e-2)" "unprognostic (2.35e-1)" "unprognostic (2.37e-1)" "unprognostic (1.90e-1)" "unprognostic (1.20e-3)" "prognostic unfavorable (1.20e-4)" "unprognostic (1.80e-1)" "unprognostic (5.63e-2)" "unprognostic (2.33e-1)" "unprognostic (2.87e-2)" "unprognostic (3.16e-1)" "prognostic unfavorable (4.14e-6)" "unprognostic (1.56e-1)" "unprognostic (1.85e-1)" "unprognostic (2.48e-1)" "unprognostic (1.00e-1)" 57.0 63.6 32.5 54.7 34.9 66.7 66.2 33.6 38.8 43.3 32.5 55.7 58.7 46.0 52.3 54.5 41.9 38.6 88.1 36.1 37.5 63.1 88.2 44.6 69.3 36.1 35.8 38.1 69.3 49.4 42.4 41.2 38.9 50.7 61.4 71.9 53.3 49.4 129.9 60.1 47.6 53.2 32.1 51.3 59.1 42.3 37.1 80.8 48.9 89.4 78.6 58.4 45.3 41.6 144.9 91.9 73.5 116.7 105.9 133.0 180.0 118.8 124.8 119.4 103.8 170.7 172.4 204.1 235.0 97.3 76.5 143.1 110.3 103.7 129.8 128.6 80.4 124.7 80.5 156.5 144.5 173.3 106.4 112.1 145.8 152.2 199.4 93.3 119.2 185.2 274.5 141.2 125.6 192.0 152.6 200.9 130.1 225.2 146.9 124.2 92.1 218.9 142.5 136.0 84.9 150.4 113.9 331.9 211.6 135.1 206.4 279.8 102.8 100.5 106.1 126.0 202.6 152.9 245.9 235.3 100.2 151.6 132.7 65.4 110.5 61.6 110.1 134.2 179.0 141.5 155.8 133.9 152.0 121.1 192.5 167.5 47.8 136.0 128.0 99.1 173.1 162.1 32.5 34.9 33.6 38.8 36.1 37.5 36.1 35.8 38.9 32.1 37.1 41.6 31.8 44.8 43.6 34.0 59.2 54.9 67.2 94.2 52.9 28.2 54.6 43.8 106.2 51.5 68.3 16.5 20.9 76.2 45.0 33.2 66.5 79.8 19.0 44.9 40.5 38.1 25.7 63.8 52.7 78.6 98.5 41.3 35.7 38.7 62.1 34.9 33.2 57.4 77.8 13.5 57.4 41.9 59.0 59.4 62.9 15.3 32.3 53.0 35.6 30.9 83.7 22.2 55.6 26.7 47.1 73.8 30.8 25.2 52.4 81.7 41.7 78.0 61.2 46.4 13.1 33.7 45.1 48.3 29.3 51.1 63.1 141.6 66.4 73.3 62.5 73.5 DHODH ENSG00000102967 "Dihydroorotate dehydrogenase (quinone)" Q02127 16 72008588-72027664 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Pyrimidine biosynthesis" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "liver: 105.9" "Cell type enriched" "Detected in many" 5 "Hepatocytes: 124.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010123, HPA011942" Approved Enhanced Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 15: Hepatocytes - Hemostasis" Mitochondria "Nucleoplasm, Cytosol" "HPA010123: AB_1847648, HPA011942: AB_1847649" "unprognostic (4.88e-2)" "unprognostic (1.10e-1)" "unprognostic (1.90e-1)" "unprognostic (2.12e-2)" "unprognostic (1.41e-3)" "unprognostic (2.10e-1)" "unprognostic (4.27e-2)" "unprognostic (1.31e-2)" "unprognostic (1.26e-1)" "unprognostic (2.68e-1)" "unprognostic (2.14e-1)" "unprognostic (6.40e-2)" "unprognostic (9.26e-3)" "unprognostic (1.98e-1)" "unprognostic (1.97e-1)" "unprognostic (1.14e-1)" "unprognostic (1.81e-1)" 7.4 4.8 3.1 4.2 3.6 3.9 5.8 3.7 3.7 4.0 3.7 5.4 3.9 5.4 2.8 4.2 6.1 2.3 13.8 2.9 2.5 8.0 105.9 3.9 4.2 3.4 3.3 4.9 4.2 6.2 2.5 2.7 3.3 4.0 5.8 3.2 5.4 4.5 10.0 4.5 3.1 5.7 2.1 4.1 4.1 3.6 3.4 3.9 4.1 8.1 5.5 3.9 3.4 5.2 12.5 25.7 6.9 12.1 3.8 5.0 13.9 10.5 4.2 15.6 11.6 20.4 11.1 27.8 13.6 5.7 8.6 12.5 13.7 11.4 18.2 6.0 13.3 15.4 12.6 20.3 10.6 21.4 10.8 4.9 11.3 18.6 19.7 4.7 11.3 18.3 23.9 4.4 9.7 32.7 20.2 17.0 15.9 21.1 10.0 24.9 9.6 29.4 9.4 7.8 8.5 10.2 14.1 14.8 6.8 8.7 13.0 10.3 5.1 14.1 8.3 13.1 15.2 8.8 18.7 46.3 7.1 22.4 12.8 6.1 8.4 1.0 9.4 8.8 12.9 12.0 8.5 9.3 14.5 11.7 11.7 12.6 2.1 10.1 6.3 13.5 8.0 7.2 3.1 3.6 3.7 3.7 2.9 2.5 3.4 3.3 3.3 2.1 3.4 5.2 6.3 3.2 13.1 1.6 7.1 5.6 7.8 11.2 6.8 5.6 6.6 7.1 14.8 15.7 5.5 7.3 4.2 12.3 6.9 1.6 5.9 10.3 2.9 3.8 6.3 9.1 1.2 7.8 2.0 5.1 12.4 7.4 2.6 3.2 8.2 10.2 5.3 124.1 7.9 3.3 2.3 6.6 10.2 6.0 3.1 3.6 2.8 3.3 12.4 1.0 3.8 5.2 8.2 4.0 4.4 5.9 2.4 2.2 4.6 11.2 1.0 20.8 8.1 5.2 0.0 9.7 9.1 6.8 8.1 5.0 3.8 2.9 4.3 13.5 6.7 4.2 DIABLO "DFNA64, DIABLO-S, FLJ10537, FLJ25049, SMAC" ENSG00000184047 "Diablo IAP-binding mitochondrial protein" Q9NR28 12 122207663-122227456 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 31.3;Plasma cells: 29.2;Squamous epithelial cells: 30.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001825, CAB003857, CAB016688" Supported Enhanced Mitochondria NA Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 43: Testis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Mitochondria "CAB003857: AB_365498, CAB016688: AB_1615783, HPA001825: AB_1857247" "unprognostic (3.67e-2)" "unprognostic (1.90e-1)" "unprognostic (1.11e-1)" "unprognostic (3.10e-3)" "unprognostic (1.64e-1)" "unprognostic (2.38e-3)" "unprognostic (1.40e-3)" "unprognostic (5.06e-2)" "unprognostic (1.48e-1)" "unprognostic (1.03e-1)" "unprognostic (1.33e-2)" "unprognostic (4.05e-2)" "prognostic unfavorable (5.35e-4)" "unprognostic (6.68e-2)" "unprognostic (2.36e-1)" "unprognostic (2.00e-1)" "unprognostic (1.40e-1)" 23.8 34.3 29.8 17.3 30.8 32.5 25.3 33.7 36.8 21.4 30.4 28.7 21.7 27.0 36.1 30.8 23.3 18.0 30.3 28.7 32.0 34.5 39.6 21.2 21.0 32.0 31.4 27.8 27.7 32.2 41.4 25.8 32.1 21.9 24.5 27.5 28.9 19.5 37.4 25.4 26.9 20.5 33.6 24.3 26.6 53.2 31.0 26.9 25.8 34.5 24.9 32.0 24.5 33.4 49.0 94.7 65.4 44.7 45.9 44.6 50.2 49.5 48.3 56.9 50.8 82.4 24.9 59.2 45.4 45.2 42.4 47.4 72.2 59.3 67.0 51.1 56.4 65.2 36.6 76.7 65.3 71.0 25.9 62.2 41.3 67.3 100.1 64.4 66.8 57.9 75.9 24.5 56.1 72.4 58.6 103.8 52.9 69.5 88.0 52.3 65.2 65.4 64.4 74.7 61.7 62.6 66.1 26.2 54.8 73.3 87.9 49.2 46.0 43.7 53.6 50.0 45.4 52.8 95.5 84.3 55.8 53.6 58.8 43.3 39.8 39.8 39.9 41.4 37.8 46.3 36.4 37.2 48.3 36.4 35.6 36.1 17.9 45.5 40.1 37.5 46.3 42.0 29.8 30.8 33.7 36.8 28.7 32.0 32.0 31.4 32.1 33.6 31.0 33.4 0.2 0.0 0.6 7.2 19.7 5.0 5.9 7.6 31.3 7.3 0.0 0.0 1.3 10.0 3.3 0.0 4.2 11.3 3.0 8.2 0.0 0.2 6.3 0.0 0.0 3.8 7.3 20.4 14.5 0.0 10.8 7.7 25.5 0.0 4.5 0.0 5.3 2.9 6.5 3.3 14.1 8.8 8.2 3.3 3.6 4.6 5.6 7.1 3.6 3.7 2.7 7.6 9.2 9.0 15.1 0.2 11.9 3.4 29.2 3.9 16.8 0.1 1.7 11.1 6.6 2.6 4.9 19.2 16.3 30.4 4.8 13.4 13.2 0.0 9.9 3.9 ECHS1 SCEH ENSG00000127884 "Enoyl-CoA hydratase, short chain 1" P30084 10 133362485-133373354 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Lyase "Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1128.7" "Cell type enhanced" "Detected in all" "Hepatocytes: 1476.3;Proximal tubular cells: 2336.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003783, HPA021995, HPA022476" Enhanced Enhanced Mitochondria NA NA 1200000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "CAB003783: , HPA021995: AB_1847974, HPA022476: AB_1847975" "unprognostic (3.68e-1)" "unprognostic (2.46e-3)" "unprognostic (9.57e-2)" "unprognostic (4.70e-2)" "unprognostic (1.59e-1)" "unprognostic (3.14e-1)" "unprognostic (2.51e-3)" "unprognostic (2.30e-1)" "unprognostic (1.82e-2)" "unprognostic (2.28e-2)" "unprognostic (1.60e-1)" "unprognostic (1.27e-1)" "prognostic favorable (8.57e-5)" "unprognostic (2.84e-2)" "unprognostic (1.19e-2)" "unprognostic (3.04e-2)" "unprognostic (2.50e-2)" 302.4 127.1 127.7 53.7 127.8 43.9 116.9 131.3 136.1 59.8 149.7 143.1 171.6 47.0 89.3 107.9 90.5 66.7 226.4 133.1 129.9 481.7 1128.7 48.5 52.4 129.4 129.9 71.3 96.8 98.7 74.3 73.6 128.8 102.0 104.6 39.8 163.4 123.2 294.3 68.2 153.6 59.4 130.3 48.4 84.5 52.6 134.6 40.0 88.5 271.6 59.0 87.4 57.8 136.0 185.1 229.2 120.4 303.4 173.0 111.4 110.5 132.2 175.9 183.2 154.1 509.5 174.0 139.2 111.9 151.4 94.4 167.7 160.2 136.1 132.0 107.4 281.2 138.5 128.1 367.2 145.0 180.4 93.5 124.5 115.9 121.2 153.6 160.8 165.1 98.3 127.8 117.4 181.6 443.9 90.7 352.0 84.4 289.8 272.1 152.8 146.4 74.6 227.8 236.0 78.1 123.4 137.0 224.1 178.9 69.4 174.8 171.5 132.1 81.3 115.9 169.9 177.4 87.0 58.8 159.8 192.4 98.8 68.7 96.1 184.7 86.8 105.5 212.2 137.6 178.7 117.8 115.8 242.6 148.9 119.3 115.8 19.8 166.0 168.1 104.9 123.0 233.0 127.7 127.8 131.3 136.1 133.1 129.9 129.4 129.9 128.8 130.3 134.6 136.0 99.2 44.8 82.7 16.3 60.5 68.2 86.9 271.8 62.6 57.0 98.5 119.6 255.2 210.1 161.5 174.7 6.2 470.2 34.0 298.6 565.4 162.8 29.9 148.9 92.7 71.4 131.7 72.2 11.6 101.1 163.5 92.5 87.7 226.4 91.2 120.0 88.5 1476.3 221.1 45.4 11.0 223.0 175.0 92.1 61.5 39.1 77.6 88.0 135.2 10.3 113.0 145.2 45.3 10.6 24.3 107.8 248.6 91.7 57.5 88.0 486.2 2336.5 93.2 55.2 85.5 57.0 98.8 52.9 66.1 125.2 76.3 299.1 62.5 220.0 317.2 127.8 ECI1 DCI ENSG00000167969 "Enoyl-CoA delta isomerase 1" P42126 16 2239402-2252300 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 301.3;Hepatocytes: 246.5;Proximal tubular cells: 272.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041746, HPA043227" Enhanced Enhanced Mitochondria NA NA 7300000 "Cluster 26: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA041746: AB_10960693, HPA043227: AB_10960273" "unprognostic (4.99e-2)" "prognostic favorable (3.04e-5)" "unprognostic (3.75e-1)" "unprognostic (2.92e-3)" "unprognostic (8.90e-2)" "unprognostic (2.85e-2)" "prognostic favorable (1.07e-4)" "unprognostic (1.98e-1)" "unprognostic (2.17e-1)" "unprognostic (5.14e-3)" "unprognostic (6.32e-2)" "unprognostic (2.66e-2)" "prognostic favorable (8.99e-8)" "unprognostic (2.61e-2)" "unprognostic (3.31e-1)" "unprognostic (1.97e-1)" "unprognostic (6.08e-3)" 51.5 57.3 35.9 12.7 39.2 19.6 52.0 38.6 45.9 46.2 61.6 74.0 59.9 44.9 10.6 57.0 50.7 11.3 189.7 32.1 38.0 123.2 235.7 37.2 13.8 39.1 37.8 38.6 74.7 43.8 50.4 14.6 35.0 56.6 15.0 12.8 78.7 24.2 220.6 49.7 58.8 9.3 37.3 35.3 69.5 18.2 42.0 13.4 105.0 87.8 9.5 50.3 43.6 36.5 29.5 68.0 25.7 107.4 9.6 13.6 96.6 29.5 19.1 23.1 33.7 120.0 88.0 42.3 71.2 17.7 16.9 71.6 29.6 27.5 3.2 74.2 157.1 12.9 61.7 151.7 87.3 38.6 6.0 25.2 63.1 18.9 41.7 16.4 23.6 1.1 71.7 87.1 8.0 119.1 4.0 57.8 60.1 46.8 68.8 134.3 27.7 207.1 45.5 32.5 88.8 56.2 70.0 131.4 92.7 12.6 84.7 67.7 19.6 18.4 68.0 19.9 33.0 95.8 61.0 72.2 23.9 35.4 26.2 1.7 3.6 1.6 1.9 3.8 3.1 4.4 2.8 1.6 3.0 4.9 3.4 2.9 2.0 3.6 2.5 3.6 4.0 0.8 35.9 39.2 38.6 45.9 32.1 38.0 39.1 37.8 35.0 37.3 42.0 36.5 47.1 3.2 28.2 13.4 28.0 21.3 115.6 11.3 21.1 53.2 77.2 95.1 92.3 94.4 15.0 77.3 43.8 179.6 20.5 151.7 301.3 35.1 10.9 128.2 54.8 28.2 45.5 61.7 4.2 36.9 80.7 33.1 33.1 122.8 5.7 62.2 34.2 246.5 47.9 21.9 6.7 105.9 20.3 31.0 23.8 5.3 24.5 29.8 39.2 4.7 17.5 89.9 5.2 13.0 10.0 33.2 91.1 24.0 36.8 72.8 176.1 272.3 14.6 77.6 0.0 73.4 42.7 6.3 19.6 32.9 22.3 109.9 21.7 50.2 104.7 110.5 ECI2 "ACBD2, DRS1, HCA88, PECI" ENSG00000198721 "Enoyl-CoA delta isomerase 2" O75521 6 4115693-4135597 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 422.7" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 293.6;Distal tubular cells: 428.4;Proximal tubular cells: 577.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022130, HPA031626" Enhanced Enhanced Peroxisomes,Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Peroxisomes, Mitochondria" "HPA022130: AB_1855176, HPA031626: AB_2673965" "unprognostic (2.36e-1)" "unprognostic (1.76e-2)" "unprognostic (1.71e-2)" "unprognostic (1.04e-2)" "unprognostic (1.00e-2)" "prognostic unfavorable (2.85e-4)" "unprognostic (1.17e-3)" "unprognostic (4.97e-2)" "unprognostic (9.49e-2)" "unprognostic (3.95e-3)" "unprognostic (3.17e-2)" "unprognostic (5.75e-2)" "prognostic favorable (2.04e-6)" "unprognostic (1.40e-1)" "unprognostic (1.23e-1)" "unprognostic (8.45e-2)" "unprognostic (1.34e-1)" 53.6 123.6 43.9 21.0 47.7 21.5 65.0 46.5 63.7 60.0 50.5 53.3 64.0 44.9 102.1 26.7 49.2 40.1 150.9 42.4 47.8 236.0 422.7 28.6 20.0 45.0 45.6 71.4 159.8 53.2 52.6 37.7 44.2 45.2 55.4 31.8 29.9 36.3 198.4 22.7 59.6 35.5 45.3 30.1 103.5 30.9 49.0 33.5 37.0 236.4 21.8 31.6 26.8 45.5 82.8 45.1 72.8 161.0 89.7 131.4 8.8 114.0 116.7 122.1 107.7 34.0 12.4 3.6 139.6 126.0 111.0 41.6 83.6 67.4 179.5 30.4 95.8 44.0 59.7 186.8 51.3 40.4 20.7 90.6 40.6 106.2 58.4 166.0 262.9 136.2 146.2 31.1 118.6 33.4 113.9 100.7 49.5 8.1 158.7 108.8 90.8 1.5 67.2 16.8 1.8 33.7 6.8 48.2 107.6 131.0 109.8 18.9 268.6 92.4 49.8 82.7 69.8 46.8 88.7 8.4 47.9 34.7 73.0 19.2 36.4 17.4 41.5 28.4 57.1 45.8 48.8 58.3 58.9 51.9 59.8 59.2 1.2 66.0 43.3 45.3 57.9 41.1 43.9 47.7 46.5 63.7 42.4 47.8 45.0 45.6 44.2 45.3 49.0 45.5 61.0 28.9 25.2 17.0 24.4 18.2 48.6 50.3 22.2 14.3 33.3 41.0 165.8 78.6 40.1 36.8 12.5 293.6 29.3 32.0 428.4 53.2 63.1 60.8 43.1 48.0 52.1 77.6 10.7 175.5 29.0 55.2 34.7 57.0 23.4 68.6 53.9 162.2 64.3 18.5 11.9 41.6 20.3 22.0 19.2 50.6 63.3 23.5 35.6 14.0 34.7 77.7 21.6 8.5 18.2 80.4 37.5 50.8 28.3 24.7 120.6 577.0 83.6 46.4 26.3 46.8 33.9 46.5 35.6 24.9 12.8 101.9 41.2 224.0 60.8 22.3 EFEMP1 "DHRD, FBLN3, FBNL, MTLV, S1-5" ENSG00000115380 "EGF containing fibulin extracellular matrix protein 1" Q12805 2 55865967-55924139 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 367.7;Cytotrophoblasts: 1365.8;Fibroblasts: 309.7;Syncytiotrophoblasts: 889.6" "Cancer enhanced" "Detected in all" "glioma: 94.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HSkMC: 953.6;hTERT-RPE1: 2226.5;HUVEC TERT2: 4270.9;TIME: 3554.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016368, HPA049806, HPA070841, HPA071588" Supported Supported Mitochondria "Secreted to extracellular matrix" NA NA 1900000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "CAB016368: AB_2277777, HPA049806: , HPA070841: AB_2686319, HPA071588: " "unprognostic (8.21e-2)" "unprognostic (7.68e-2)" "unprognostic (9.01e-3)" "prognostic unfavorable (4.72e-4)" "unprognostic (3.43e-2)" "unprognostic (1.73e-2)" "unprognostic (4.86e-2)" "unprognostic (1.38e-1)" "unprognostic (3.46e-1)" "unprognostic (9.07e-2)" "unprognostic (1.55e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.89e-8)" "unprognostic (3.15e-3)" "unprognostic (4.94e-2)" "unprognostic (3.09e-1)" "prognostic unfavorable (6.68e-5)" 240.5 55.7 57.0 57.2 82.8 0.2 115.3 57.1 88.8 54.9 180.7 74.6 22.5 73.2 128.4 51.5 134.8 140.4 187.8 47.5 75.6 57.4 12.9 150.1 27.2 80.8 121.1 175.1 29.2 17.6 22.6 329.7 65.5 58.4 91.0 42.8 87.7 161.2 14.7 55.2 45.3 93.5 72.2 42.4 46.9 8.0 71.0 16.8 139.1 93.8 21.2 203.9 77.3 71.9 358.4 3.1 8.5 0.3 320.9 217.1 0.8 208.1 233.7 25.2 20.5 0.0 18.0 0.5 140.4 234.3 22.1 323.4 1.6 234.6 8.9 1.0 1.0 0.3 87.4 0.2 843.2 0.3 0.6 953.6 117.5 21.9 260.9 2226.5 4270.9 0.5 1.2 0.2 99.2 36.7 2.6 0.5 4.2 0.1 0.8 0.2 0.3 0.9 9.8 7.3 2.0 0.4 284.6 105.0 0.7 8.1 289.8 1.5 3554.3 1.5 107.5 397.9 138.5 13.7 0.5 1.4 73.1 0.3 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 57.0 82.8 57.1 88.8 47.5 75.6 80.8 121.1 65.5 72.2 71.0 71.9 26.6 250.0 109.1 234.1 0.1 79.4 79.1 367.7 42.1 2.8 6.2 78.2 12.5 12.8 98.2 27.6 0.0 1365.8 0.4 0.0 9.8 36.2 0.5 2.2 38.9 73.5 0.0 0.0 1.0 25.6 173.0 309.7 6.1 2.1 2.5 3.9 48.5 0.7 94.9 0.0 4.7 0.0 40.7 0.8 33.9 0.9 42.6 3.2 17.8 6.5 0.6 137.3 0.0 2.5 0.8 2.8 0.0 0.0 1.5 24.2 0.0 14.7 88.8 4.7 0.0 7.0 28.7 0.4 1.8 6.0 31.7 889.6 5.0 61.3 0.0 6.2 EIF4E2 "4EHP, EIF4EL3, IF4e" ENSG00000135930 "Eukaryotic translation initiation factor 4E family member 2" O60573 2 232550674-232583644 "Predicted intracellular proteins" "Protein biosynthesis, RNA-mediated gene silencing, Translation regulation" "Initiation factor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 302.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019253, HPA077074" Enhanced Mitochondria,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria Cytosol "HPA019253: AB_1848092, HPA077074: " "unprognostic (3.44e-2)" "unprognostic (2.70e-1)" "unprognostic (1.30e-1)" "unprognostic (3.83e-2)" "unprognostic (1.63e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (2.38e-4)" "unprognostic (1.42e-1)" "unprognostic (5.62e-3)" "unprognostic (1.42e-2)" "unprognostic (1.31e-1)" "unprognostic (1.21e-2)" "unprognostic (1.36e-2)" "unprognostic (7.74e-2)" "unprognostic (3.34e-3)" "unprognostic (1.88e-1)" "unprognostic (9.38e-2)" 40.8 35.9 27.8 52.4 29.0 58.3 43.0 29.2 34.3 35.4 26.9 67.4 50.6 41.6 36.9 51.9 33.2 42.8 38.3 28.1 29.2 63.9 93.2 45.2 49.2 30.4 28.7 33.6 40.8 36.2 24.5 56.9 31.5 34.8 77.2 34.4 38.8 31.8 153.1 50.2 52.5 56.1 27.1 42.5 51.1 42.2 29.5 41.9 36.2 62.5 61.9 47.3 34.3 31.1 104.9 99.5 108.7 79.3 83.4 110.2 161.9 144.9 88.3 101.9 107.8 109.8 100.3 109.0 39.0 151.6 116.7 88.6 128.2 131.2 128.9 98.6 122.0 146.6 97.4 149.9 98.8 213.0 130.7 103.1 98.1 105.5 78.5 102.8 172.1 53.0 139.0 34.7 118.7 201.4 83.1 171.0 174.3 124.1 83.5 73.2 231.7 72.3 209.6 133.2 98.7 135.5 77.0 86.6 95.3 117.2 81.3 145.3 148.6 88.3 114.9 96.6 106.1 67.3 71.0 139.8 100.0 109.4 78.9 299.2 205.7 194.4 63.6 220.0 51.4 62.2 65.8 67.7 179.3 60.5 55.1 56.1 132.1 70.7 205.9 70.9 114.7 155.5 27.8 29.0 29.2 34.3 28.1 29.2 30.4 28.7 31.5 27.1 29.5 31.1 37.2 41.7 57.3 11.8 40.1 38.0 78.2 127.4 31.3 19.8 41.5 49.3 36.9 65.8 85.4 35.0 18.8 142.0 53.6 109.1 74.3 164.5 129.6 45.6 63.1 46.9 66.0 50.7 20.0 151.5 204.3 60.2 48.9 68.6 43.7 47.2 50.0 119.9 125.4 20.2 19.3 111.3 120.1 90.8 87.5 302.4 38.2 72.6 30.2 10.3 135.8 29.3 51.5 12.1 29.7 159.8 109.3 38.7 51.8 96.8 139.1 170.8 58.8 22.3 26.3 38.8 118.5 68.4 56.0 59.7 51.1 182.5 42.7 92.3 87.9 120.4 ERAL1 HERA-B ENSG00000132591 "Era like 12S mitochondrial rRNA chaperone 1" O75616 17 28855010-28861061 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ribosome biogenesis" "RNA-binding, rRNA-binding" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021425, HPA024423" Supported Enhanced Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 3: Monocytes - Immune response regulation" Mitochondria Cytosol "HPA021425: AB_1848228, HPA024423: AB_1848229" "unprognostic (1.03e-1)" "unprognostic (9.16e-2)" "unprognostic (5.36e-2)" "unprognostic (1.77e-2)" "unprognostic (3.55e-1)" "unprognostic (8.37e-3)" "prognostic unfavorable (3.59e-4)" "unprognostic (8.20e-2)" "unprognostic (7.04e-2)" "unprognostic (2.70e-1)" "unprognostic (8.57e-3)" "unprognostic (5.76e-1)" "unprognostic (1.08e-1)" "unprognostic (1.18e-1)" "unprognostic (2.49e-1)" "unprognostic (2.62e-1)" "unprognostic (5.79e-2)" 20.3 32.5 47.6 17.5 47.7 18.5 23.4 48.4 61.7 20.9 44.7 25.8 22.0 22.1 22.7 28.8 26.2 15.1 41.0 48.0 48.0 29.2 41.2 18.3 22.0 47.9 47.3 25.6 23.6 36.2 18.9 24.5 48.1 21.0 28.1 16.9 22.6 23.9 52.7 26.3 19.9 26.5 47.7 21.0 26.3 17.9 48.4 23.8 19.2 51.8 29.6 22.1 20.6 48.9 50.4 96.2 55.9 63.1 59.1 40.6 53.4 40.1 56.2 117.1 95.9 94.5 31.7 64.1 47.0 68.8 87.9 55.2 102.0 90.0 97.5 63.6 119.8 52.2 60.6 95.8 75.5 63.0 45.7 53.5 78.1 95.3 89.3 46.1 97.2 80.4 104.4 39.9 66.4 78.7 66.1 98.4 50.6 91.8 46.0 59.7 87.6 83.4 71.3 56.1 58.6 47.1 64.5 155.6 51.6 82.2 110.0 71.8 39.7 48.1 53.1 52.9 84.6 32.0 62.3 69.9 51.4 54.4 49.1 25.5 34.2 14.4 32.2 44.6 24.2 38.9 26.9 23.5 54.9 36.3 30.8 32.2 2.6 42.8 31.6 28.7 32.1 30.8 47.6 47.7 48.4 61.7 48.0 48.0 47.9 47.3 48.1 47.7 48.4 48.9 12.4 6.4 2.8 5.9 14.0 8.0 12.7 33.9 12.0 10.9 14.9 18.3 8.0 17.2 13.9 11.0 6.2 69.1 9.9 13.4 37.2 28.1 1.0 11.1 14.0 14.4 21.6 20.4 7.2 21.6 55.2 15.8 19.9 13.3 5.1 24.8 14.3 21.7 35.6 11.8 7.8 15.0 26.4 8.5 6.7 5.4 14.3 12.4 10.6 3.7 66.6 16.4 9.2 5.5 4.3 21.1 12.9 15.8 29.2 15.1 20.0 33.3 9.7 9.0 19.7 11.0 15.6 22.3 21.7 25.4 11.6 51.7 10.4 25.0 26.6 9.9 ETFA "EMA, GA2, MADD" ENSG00000140374 "Electron transfer flavoprotein subunit alpha" P13804 15 76215353-76311472 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport" "Disease variant, Glutaricaciduria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 389.7;tongue: 493.5" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 402.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018990, HPA018993, HPA018996, HPA024089" Enhanced Enhanced Mitochondria NA NA 680000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA018990: AB_1848277, HPA018993: AB_1848275, HPA018996: AB_1848276, HPA024089: AB_1848278" "unprognostic (3.44e-3)" "unprognostic (1.50e-1)" "unprognostic (2.29e-1)" "unprognostic (2.26e-1)" "unprognostic (3.71e-3)" "unprognostic (5.99e-2)" "unprognostic (6.81e-3)" "unprognostic (3.02e-1)" "unprognostic (5.01e-2)" "unprognostic (6.01e-2)" "unprognostic (3.38e-3)" "unprognostic (1.99e-1)" "prognostic favorable (5.04e-8)" "unprognostic (2.87e-1)" "unprognostic (4.90e-2)" "unprognostic (9.22e-2)" "unprognostic (2.90e-2)" 93.0 112.3 33.8 55.0 36.0 63.0 70.4 36.0 54.6 38.7 40.3 131.4 135.6 27.0 30.6 85.1 30.1 44.7 243.0 34.2 37.6 180.0 389.7 39.0 60.9 35.6 35.7 25.6 81.6 71.0 13.9 70.9 36.0 42.2 123.5 34.3 49.3 38.2 300.8 40.1 116.3 65.7 35.5 38.8 67.7 28.4 38.2 54.5 38.7 493.5 65.9 74.0 33.1 36.9 122.4 196.7 128.2 134.8 141.7 149.1 201.0 144.4 166.2 183.0 162.8 175.3 221.3 203.5 141.3 144.3 138.5 304.6 502.7 200.2 211.9 245.8 98.0 222.2 131.4 205.2 114.7 214.5 158.7 112.7 185.9 93.1 153.5 100.0 187.8 64.7 214.1 205.2 190.3 191.2 44.9 178.2 99.9 225.3 58.4 192.8 158.6 272.8 202.1 386.9 133.3 67.2 218.2 492.2 205.0 294.4 254.1 223.4 111.4 178.2 119.5 157.0 177.4 99.0 221.0 255.9 127.8 281.1 128.5 50.0 120.3 82.7 65.4 110.3 61.7 77.3 60.6 67.6 159.4 67.3 48.8 60.1 30.2 122.9 96.1 63.4 95.8 141.9 33.8 36.0 36.0 54.6 34.2 37.6 35.6 35.7 36.0 35.5 38.2 36.9 65.7 57.7 41.6 45.1 54.3 53.4 110.8 151.5 44.9 13.1 47.2 46.4 352.9 65.8 84.5 36.8 22.9 277.4 61.1 250.9 209.4 106.5 11.7 29.5 45.1 51.8 65.4 117.8 26.0 84.1 180.8 66.8 90.2 37.0 38.6 53.1 48.9 348.8 132.3 53.8 31.5 141.6 89.5 79.0 84.5 7.9 59.4 103.0 56.9 28.1 129.0 26.7 85.5 37.2 46.9 92.1 176.2 58.3 87.8 92.4 231.1 402.9 50.2 20.4 46.0 44.0 113.7 66.4 40.5 79.5 57.1 300.2 55.5 123.4 187.3 162.0 ETFB ENSG00000105379 "Electron transfer flavoprotein subunit beta" P38117 19 51345169-51366388 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport" "Disease variant, Glutaricaciduria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 493.6" "Cell type enhanced" "Detected in all" "Hepatocytes: 1105.3;Proximal enterocytes: 710.7;Proximal tubular cells: 1118.7" "Cancer enhanced" "Detected in all" "liver cancer: 53.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 1693.9;OE19: 770.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018910, HPA018921, HPA018923" Supported Enhanced Mitochondria NA NA 170000 "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA018910: AB_1848280, HPA018921: AB_1848281, HPA018923: AB_1848282" "unprognostic (1.44e-1)" "prognostic favorable (6.45e-4)" "unprognostic (8.66e-2)" "unprognostic (3.08e-1)" "unprognostic (1.77e-1)" "unprognostic (3.94e-2)" "unprognostic (3.20e-1)" "unprognostic (6.93e-3)" "unprognostic (2.63e-2)" "unprognostic (7.79e-2)" "unprognostic (1.23e-1)" "unprognostic (4.75e-1)" "prognostic favorable (6.45e-5)" "unprognostic (2.19e-1)" "unprognostic (2.54e-1)" "unprognostic (4.83e-1)" "unprognostic (1.99e-1)" 159.1 171.5 121.1 44.0 134.4 70.2 115.3 134.8 145.5 55.7 123.0 97.6 136.3 48.9 16.9 140.7 53.3 62.7 387.8 112.8 120.6 144.5 493.6 50.4 58.2 129.8 124.8 55.2 81.9 106.3 73.1 39.0 125.7 55.2 41.2 24.1 172.2 37.9 280.7 79.0 129.7 31.7 119.9 64.5 90.0 53.6 132.4 81.4 70.3 280.3 36.9 65.6 69.0 137.0 118.9 304.3 41.3 113.9 129.4 150.4 65.6 82.4 61.0 63.5 63.1 257.3 192.1 121.5 80.2 129.8 33.8 104.0 83.3 171.1 19.2 182.0 323.3 98.1 188.9 1693.9 141.8 92.1 67.6 235.3 50.3 86.1 88.2 79.2 54.9 115.0 146.6 130.2 83.2 243.7 95.2 86.2 26.7 770.2 372.0 104.5 114.4 224.6 88.5 135.7 91.7 44.5 184.5 49.9 94.4 29.4 130.3 86.3 77.8 65.9 67.6 71.4 73.3 195.8 130.0 109.8 335.0 135.1 172.5 127.7 190.1 119.6 104.3 212.3 137.4 281.6 156.0 134.2 225.3 303.1 163.6 136.0 97.8 205.3 165.7 265.1 225.7 140.5 121.1 134.4 134.8 145.5 112.8 120.6 129.8 124.8 125.7 119.9 132.4 137.0 90.9 80.1 93.8 15.3 75.6 65.0 114.9 196.4 55.2 77.1 129.9 170.1 243.8 234.4 122.5 121.4 31.3 240.7 58.7 440.9 571.3 188.0 139.2 67.5 70.2 76.2 168.4 120.0 4.1 140.5 206.6 93.8 128.9 48.2 88.8 63.2 144.9 1105.3 217.5 43.7 4.2 335.2 158.7 147.7 73.4 354.4 107.5 86.9 286.4 5.6 95.2 158.8 50.4 7.1 18.9 155.4 339.4 114.3 69.9 74.9 710.7 1118.7 118.8 67.9 98.6 87.4 144.5 71.0 52.8 135.3 63.6 160.1 74.0 217.3 354.4 140.3 ETHE1 "HSCO, YF13H12" ENSG00000105755 "ETHE1 persulfide dioxygenase" O95571 19 43506719-43527230 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 256.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1037.7;Paneth cells: 788.4;Proximal enterocytes: 376.3;Undifferentiated cells: 447.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 222.6;OE19: 360.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028360, HPA029028, HPA029029" Enhanced Enhanced Mitochondria No No "Cluster 28: Myeloid DCs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA028360: AB_10599297, HPA029028: AB_10602092, HPA029029: AB_10601998" "unprognostic (8.04e-2)" "unprognostic (3.33e-1)" "unprognostic (1.50e-2)" "unprognostic (2.45e-1)" "unprognostic (8.34e-2)" "unprognostic (1.25e-2)" "unprognostic (2.58e-1)" "prognostic unfavorable (9.58e-4)" "unprognostic (7.75e-2)" "unprognostic (2.28e-1)" "unprognostic (5.47e-2)" "unprognostic (3.24e-1)" "unprognostic (1.01e-1)" "unprognostic (5.27e-2)" "unprognostic (1.75e-1)" "unprognostic (9.72e-3)" "unprognostic (2.73e-2)" 24.4 27.9 16.1 34.8 17.0 45.8 26.7 16.5 17.3 28.7 15.8 256.1 85.5 18.3 29.8 81.0 20.6 21.0 18.8 15.6 17.4 40.4 52.7 30.5 23.4 17.3 17.2 13.5 28.9 16.1 19.1 26.3 16.6 27.1 226.6 3.2 40.1 18.5 22.8 27.2 77.0 35.6 17.1 27.8 37.8 3.0 18.2 19.8 24.1 21.9 41.7 34.4 39.1 17.2 54.1 68.9 14.1 49.6 75.1 50.9 5.5 82.1 222.6 69.8 71.1 21.1 54.3 0.2 60.0 79.8 22.2 42.9 20.6 123.4 19.6 26.2 6.2 13.8 29.7 59.2 34.0 19.3 18.4 52.2 95.1 26.9 76.0 92.2 52.0 49.8 9.0 87.6 35.1 35.7 22.2 18.9 3.8 360.5 32.9 26.6 6.1 12.0 153.0 110.9 0.2 16.6 20.8 74.8 50.6 23.6 22.4 34.3 41.6 10.9 46.9 13.1 15.3 23.1 20.2 1.4 48.4 83.8 57.7 24.2 63.3 1.6 41.1 34.5 48.3 20.5 47.6 39.4 95.8 7.5 36.4 35.0 2.1 29.3 22.8 17.9 50.4 40.2 16.1 17.0 16.5 17.3 15.6 17.4 17.3 17.2 16.6 17.1 18.2 17.2 32.0 22.4 23.4 3.9 25.5 34.5 82.2 242.5 57.5 9.8 85.8 95.2 9.8 47.1 84.5 55.2 0.0 191.6 38.0 1037.7 54.8 71.7 0.9 31.0 41.2 44.9 63.7 17.4 6.2 63.6 95.7 42.1 53.5 68.2 38.0 12.6 42.1 89.2 115.1 5.0 6.8 324.2 79.3 105.0 78.5 2.1 17.7 74.6 80.0 3.7 78.5 11.7 63.8 4.0 5.6 102.7 788.4 16.1 34.9 75.0 376.3 136.4 23.1 5.8 19.7 32.0 45.1 2.1 6.2 82.8 23.2 92.5 50.4 15.8 447.5 146.5 FAHD1 "C16orf36, DKFZP566J2046" ENSG00000180185 "Fumarylacetoacetate hydrolase domain containing 1" Q6P587 16 1826941-1840207 "Enzymes, Predicted intracellular proteins" "Hydrolase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 64.1" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 112.2;Proximal tubular cells: 210.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025530, HPA043226, HPA043534" Enhanced Enhanced Nucleoplasm,Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria Nucleoplasm "CAB025530: , HPA043226: AB_2678370, HPA043534: AB_2678535" "unprognostic (3.71e-1)" "unprognostic (1.25e-2)" "prognostic favorable (8.27e-4)" "unprognostic (1.99e-1)" "unprognostic (6.74e-2)" "unprognostic (1.01e-3)" "unprognostic (2.89e-2)" "unprognostic (4.32e-1)" "unprognostic (1.13e-1)" "unprognostic (5.36e-2)" "unprognostic (1.65e-1)" "unprognostic (1.38e-1)" "prognostic favorable (2.80e-14)" "unprognostic (1.02e-1)" "unprognostic (1.66e-1)" "unprognostic (1.26e-1)" "unprognostic (3.31e-2)" 12.3 21.4 9.1 8.5 9.4 10.0 9.4 9.3 11.1 8.3 9.2 22.6 36.1 9.7 8.0 19.3 6.9 12.1 19.9 10.9 11.1 64.1 58.5 7.1 7.4 10.7 10.0 8.0 15.8 12.1 9.5 7.5 10.1 9.4 14.2 6.7 11.2 10.7 30.7 17.1 27.1 8.7 8.8 8.4 21.0 10.1 9.4 7.9 7.8 24.7 6.4 11.3 11.1 9.9 20.1 44.6 20.9 36.9 27.0 19.5 12.9 32.4 16.0 21.1 22.9 28.6 20.4 12.8 26.6 20.2 32.7 40.5 16.4 25.8 19.0 19.3 39.0 11.5 38.7 67.0 26.2 20.0 21.2 25.8 33.3 19.3 12.9 17.8 27.8 15.3 12.1 12.8 26.8 92.5 10.9 30.1 12.4 18.4 33.0 24.6 28.3 36.4 76.8 24.9 40.4 33.6 42.3 33.5 52.0 13.8 49.4 13.4 41.1 34.4 24.6 20.5 17.8 18.6 42.3 15.1 22.0 14.5 15.1 15.8 40.8 16.5 25.1 51.5 22.5 37.2 24.7 27.3 42.6 32.7 27.0 24.8 3.5 38.1 38.4 33.1 28.4 24.3 9.1 9.4 9.3 11.1 10.9 11.1 10.7 10.0 10.1 8.8 9.4 9.9 14.6 25.6 16.4 2.9 11.2 14.0 13.3 29.6 13.1 19.8 12.4 15.7 42.9 27.1 17.2 42.3 27.1 22.6 10.9 50.8 50.9 57.2 89.8 16.8 19.8 16.3 29.3 36.4 8.0 39.2 14.2 15.5 17.3 18.2 5.1 13.8 9.7 35.5 30.5 18.5 8.6 25.6 24.4 9.1 14.2 45.0 14.6 13.7 16.0 4.7 18.9 17.4 20.6 3.0 6.4 34.9 36.7 15.4 4.0 11.2 112.2 210.9 14.4 24.2 13.1 12.7 16.5 9.9 9.1 27.2 24.0 15.3 9.8 30.3 52.7 9.6 FDX1 "ADX, FDX" ENSG00000137714 "Ferredoxin 1" P10109 11 110429948-110464884 "Predicted intracellular proteins" "Cholesterol metabolism, Electron transport, Lipid metabolism, Steroid metabolism, Steroidogenesis, Sterol metabolism, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "adrenal gland: 313.7" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 1139.6;Theca cells: 745.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 71.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041630, HPA062087" Enhanced Enhanced Mitochondria NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Mitochondria "HPA041630: AB_10793970, HPA062087: AB_2630366" "unprognostic (1.66e-1)" "unprognostic (1.68e-2)" "unprognostic (5.29e-3)" "unprognostic (4.67e-2)" "unprognostic (2.39e-1)" "unprognostic (4.32e-3)" "unprognostic (1.23e-2)" "unprognostic (2.07e-1)" "unprognostic (2.19e-2)" "unprognostic (4.12e-1)" "unprognostic (3.10e-2)" "unprognostic (5.48e-2)" "prognostic favorable (3.58e-7)" "prognostic favorable (2.53e-4)" "unprognostic (1.10e-1)" "unprognostic (1.94e-1)" "unprognostic (2.80e-1)" 9.0 313.7 6.9 6.8 7.5 12.1 8.5 7.5 8.6 7.4 8.7 12.9 22.0 6.2 8.2 9.3 5.9 9.1 16.3 6.8 7.6 29.6 44.3 10.8 7.9 7.3 7.8 5.4 13.4 9.3 6.1 17.7 7.6 8.2 10.7 5.3 8.6 26.3 20.6 6.2 18.4 6.1 7.5 6.7 13.5 7.6 7.9 12.0 20.3 18.5 7.5 10.5 5.5 8.8 10.2 7.0 10.6 11.6 10.1 17.8 23.5 9.2 11.2 8.0 13.5 24.1 16.7 23.8 26.4 11.9 14.2 11.8 12.4 13.9 10.8 22.9 15.8 12.0 12.0 14.8 17.7 12.7 18.8 31.3 11.4 7.3 17.1 13.8 16.5 16.2 12.2 34.4 17.3 11.3 18.2 28.3 9.5 19.3 13.1 26.4 10.1 22.1 17.4 18.1 14.4 7.4 17.5 19.7 12.5 12.3 11.7 8.7 9.8 8.0 9.8 9.8 9.9 7.7 6.4 71.7 6.0 25.5 10.5 1.8 4.5 2.8 3.8 3.3 4.1 9.7 5.2 5.4 5.2 7.5 6.2 4.4 0.5 3.4 4.6 4.0 7.4 2.6 6.9 7.5 7.5 8.6 6.8 7.6 7.3 7.8 7.6 7.5 7.9 8.8 53.2 19.2 38.1 15.0 68.6 68.3 104.3 45.4 42.7 33.0 40.3 37.0 57.1 102.9 28.3 80.9 8.4 174.3 65.7 109.5 244.6 71.4 53.4 49.6 35.6 36.7 47.9 28.8 22.6 144.8 169.4 48.1 61.2 42.0 45.7 36.3 45.0 192.7 113.3 42.1 25.8 56.2 34.6 58.4 68.3 11.0 46.9 77.3 69.4 15.0 57.3 42.3 50.4 22.1 19.6 78.5 76.5 45.5 102.7 114.2 183.9 338.7 18.6 17.3 26.3 50.6 43.6 48.0 67.0 75.3 97.5 1139.6 74.0 745.1 96.4 149.6 FDXR "ADR, ADXR" ENSG00000161513 "Ferredoxin reductase" P22570 17 74862497-74873031 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Electron transport, Lipid metabolism, Steroid metabolism, Sterol metabolism, Transport" Oxidoreductase "Deafness, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "adrenal gland: 343.1" "Group enriched" "Detected in many" 7 "Granulosa cells: 329.3;Theca cells: 794.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 89.5;Hep G2: 173.5" "Low region specificity" "Detected in all" "CAB008597, CAB009818, HPA044393, HPA053673" Enhanced Enhanced Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 52: Non-specific - Transcription" Mitochondria "CAB008597: AB_1615557, CAB009818: AB_2102601, HPA044393: AB_2678927, HPA053673: AB_2682225" "unprognostic (2.69e-2)" "unprognostic (1.17e-3)" "unprognostic (7.51e-2)" "prognostic favorable (2.38e-4)" "unprognostic (3.43e-2)" "unprognostic (1.20e-1)" "unprognostic (1.53e-1)" "unprognostic (1.68e-2)" "unprognostic (2.29e-1)" "unprognostic (1.50e-1)" "unprognostic (1.09e-1)" "unprognostic (6.30e-2)" "unprognostic (1.42e-2)" "unprognostic (1.19e-2)" "unprognostic (4.50e-2)" "unprognostic (4.03e-2)" "unprognostic (2.13e-1)" 3.9 343.1 6.9 2.4 8.4 2.2 3.8 7.8 8.1 7.8 8.6 9.7 4.6 6.7 5.1 26.0 12.9 4.1 6.0 6.6 6.7 6.5 14.9 5.3 2.9 7.6 7.9 20.5 12.9 5.9 4.1 3.0 7.5 6.7 3.2 0.5 7.1 4.4 7.7 16.4 5.6 2.3 7.4 33.9 7.6 45.6 7.0 4.7 6.0 1.7 2.5 6.2 10.5 7.5 12.5 65.6 9.6 10.8 6.8 9.1 89.5 14.8 15.9 8.6 17.1 18.3 10.8 29.6 2.6 6.2 4.8 24.9 6.9 18.4 2.5 27.9 15.2 22.6 10.6 173.5 19.0 5.0 75.1 29.2 20.3 9.1 3.1 7.0 43.9 10.9 36.1 4.8 13.4 53.4 19.7 10.6 5.5 11.8 14.5 10.6 16.4 16.2 7.1 21.0 5.2 12.1 10.0 21.7 11.2 10.9 47.4 4.7 20.5 5.9 51.9 9.4 7.4 12.7 2.3 6.5 16.1 7.7 20.6 1.7 6.0 5.0 5.6 4.5 5.0 4.8 5.1 6.8 7.3 2.4 4.4 5.4 2.0 10.3 3.4 1.4 15.4 5.2 6.9 8.4 7.8 8.1 6.6 6.7 7.6 7.9 7.5 7.4 7.0 7.5 4.0 3.2 3.9 7.5 8.2 9.7 17.8 42.6 17.1 4.9 6.6 8.4 3.8 5.7 23.3 9.2 4.2 53.2 2.8 18.6 5.9 11.1 6.5 28.2 4.3 4.6 7.1 4.0 1.4 7.9 18.9 12.9 13.7 3.5 5.7 329.3 12.5 13.9 23.1 3.3 2.2 13.1 36.7 6.2 2.7 14.9 5.9 4.6 5.4 1.0 3.9 11.4 8.2 3.0 1.3 9.0 16.9 4.5 7.1 5.2 24.9 21.7 73.6 5.1 0.0 6.2 18.3 6.3 6.1 33.7 18.2 46.1 8.6 794.1 20.3 17.4 FH ENSG00000091483 "Fumarate hydratase" P07954 1 241497603-241519755 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Tricarboxylic acid cycle" Lyase "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 276.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 173.5;Early spermatids: 226.0;Syncytiotrophoblasts: 166.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017785, HPA025770, HPA025948, HPA027341" Enhanced Supported Enhanced Mitochondria NA NA 1800000 "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB017785: , HPA025770: AB_10599603, HPA025948: AB_10602177, HPA027341: AB_10601222" "unprognostic (1.03e-2)" "unprognostic (3.82e-2)" "unprognostic (9.46e-3)" "unprognostic (2.18e-1)" "unprognostic (2.10e-1)" "unprognostic (2.07e-1)" "unprognostic (2.28e-2)" "unprognostic (1.55e-1)" "unprognostic (5.14e-2)" "unprognostic (1.85e-2)" "unprognostic (1.27e-2)" "unprognostic (1.09e-1)" "prognostic favorable (2.76e-7)" "unprognostic (1.05e-1)" "unprognostic (1.05e-1)" "unprognostic (4.41e-2)" "unprognostic (1.24e-2)" 43.4 75.2 30.4 31.0 33.3 31.4 37.3 33.5 42.0 28.9 43.9 66.8 68.2 36.9 26.1 51.1 27.9 23.7 179.0 33.9 33.1 101.8 276.4 26.4 30.0 31.8 31.0 24.9 38.1 95.0 31.1 32.1 32.1 33.5 69.0 58.8 42.0 38.4 213.4 40.3 59.1 42.0 32.4 30.1 53.6 44.4 32.7 31.3 34.6 229.3 40.4 37.5 33.7 33.0 129.2 105.6 97.9 89.0 93.9 110.0 154.9 155.7 121.1 171.6 107.1 152.2 78.0 81.1 100.3 119.9 75.0 178.4 151.7 115.8 148.4 93.5 48.9 76.3 102.2 131.4 84.1 180.2 66.7 80.2 70.7 96.6 108.0 60.2 107.2 175.8 236.3 101.7 126.9 64.3 156.6 120.1 104.5 186.2 223.6 127.4 107.2 365.7 167.4 107.6 125.4 108.4 131.1 153.3 104.0 67.2 117.1 120.9 106.5 76.6 98.9 137.0 264.0 90.3 103.7 97.3 85.7 203.5 112.6 11.9 22.8 4.9 16.1 33.3 21.0 27.2 18.8 15.1 46.7 25.1 22.3 21.1 1.3 18.3 29.1 23.1 23.8 16.7 30.4 33.3 33.5 42.0 33.9 33.1 31.8 31.0 32.1 32.4 32.7 33.0 17.1 38.5 30.2 9.4 25.0 20.0 24.6 69.5 17.1 24.7 19.9 17.5 173.5 35.8 40.0 23.9 14.6 101.6 13.7 44.0 78.2 60.4 226.0 25.4 23.5 18.6 18.0 37.7 12.7 45.0 58.7 25.5 26.5 25.4 19.0 24.9 13.6 80.4 50.7 35.3 14.9 40.6 48.8 18.5 14.4 37.4 23.9 23.9 24.9 8.4 27.9 35.0 10.3 8.0 14.4 29.4 35.7 26.7 41.3 19.0 66.1 86.0 29.2 39.1 39.5 27.7 67.9 84.7 47.1 32.1 18.6 166.1 14.9 48.4 74.2 22.8 GFER "ALR, ERV1, HERV1, HPO1, HPO2, HSS" ENSG00000127554 "Growth factor, augmenter of liver regeneration" P55789 16 1984193-1987749 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor, Oxidoreductase" "Cataract, Deafness, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 183.7;Early spermatids: 168.7;Proximal enterocytes: 371.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041227, HPA063553" Approved Enhanced Mitochondria,Cytosol "Secreted to blood" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 29: Non-specific - Vesicular transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 45: Enterocytes - Digestion" "Mitochondria, Cytosol" "HPA041227: AB_10795538, HPA063553: AB_2685038" "unprognostic (5.35e-2)" "unprognostic (2.11e-2)" "unprognostic (3.08e-1)" "unprognostic (4.42e-2)" "unprognostic (3.15e-1)" "unprognostic (2.63e-1)" "unprognostic (1.27e-2)" "unprognostic (1.42e-1)" "unprognostic (1.11e-2)" "unprognostic (2.30e-1)" "unprognostic (1.56e-1)" "unprognostic (5.93e-2)" "prognostic favorable (4.06e-4)" "unprognostic (4.93e-2)" "unprognostic (3.64e-1)" "unprognostic (3.56e-1)" "unprognostic (1.09e-2)" 17.7 21.2 19.6 13.8 19.0 18.2 17.8 21.6 23.1 14.2 17.9 32.8 42.7 16.6 6.6 17.5 16.0 13.5 29.8 19.0 19.7 21.9 45.9 15.3 20.9 21.5 21.1 11.3 53.7 29.6 18.1 12.2 20.9 19.6 25.4 7.7 28.8 13.1 40.9 14.5 45.2 10.9 18.8 21.9 24.7 38.5 20.6 10.5 15.9 30.4 16.9 19.4 12.8 20.6 27.2 44.1 35.6 29.2 14.7 28.9 43.5 28.6 31.2 44.2 35.6 63.7 46.1 15.2 39.7 24.2 25.7 39.8 27.3 42.4 27.9 44.7 46.6 20.9 44.3 73.4 26.6 32.1 37.9 18.9 32.5 38.8 34.6 27.8 21.1 32.7 33.0 51.3 32.6 66.1 34.9 33.9 54.9 23.9 39.7 74.5 26.8 50.7 45.5 21.9 30.5 28.9 39.3 91.2 34.5 18.2 43.4 33.6 19.1 42.8 45.0 24.0 54.3 79.1 48.3 45.7 14.2 21.5 36.7 3.8 16.2 13.4 11.2 13.9 11.4 23.5 14.9 18.5 11.6 17.8 13.6 9.5 1.4 10.7 17.4 5.1 24.9 10.6 19.6 19.0 21.6 23.1 19.0 19.7 21.5 21.1 20.9 18.8 20.6 20.6 18.0 3.2 6.7 2.3 32.5 15.9 19.9 21.1 17.6 10.8 32.7 27.6 17.4 27.1 16.6 9.2 0.0 43.4 23.0 183.7 35.2 44.0 168.7 24.0 11.4 17.9 27.2 17.0 3.4 80.8 57.8 17.7 16.8 18.7 12.7 22.8 20.7 59.1 45.9 8.4 3.2 60.3 26.4 39.3 24.8 123.7 17.4 24.7 23.2 1.0 39.6 12.6 39.1 1.5 3.3 57.3 100.3 12.4 39.6 21.7 371.7 84.6 33.3 11.5 13.1 15.8 18.5 41.9 26.7 17.3 14.8 37.5 27.4 26.7 68.7 26.0 GRPEL2 "DKFZp451C205, FLJ23713, Mt-GrpE#2" ENSG00000164284 "GrpE like 2, mitochondrial" Q8TAA5 5 149345430-149354583 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 44.9" "Cell type enhanced" "Detected in many" "Endothelial cells: 36.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018173, HPA023211" Approved Enhanced Mitochondria NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Mitochondria "HPA018173: AB_1850358, HPA023211: AB_1850360" "unprognostic (3.13e-2)" "unprognostic (1.69e-1)" "prognostic favorable (3.87e-5)" "prognostic unfavorable (2.21e-4)" "unprognostic (3.22e-1)" "unprognostic (2.07e-2)" "prognostic unfavorable (6.16e-8)" "unprognostic (1.34e-1)" "unprognostic (8.16e-2)" "unprognostic (3.43e-2)" "unprognostic (2.21e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (4.20e-4)" "unprognostic (3.40e-1)" "unprognostic (1.79e-1)" "unprognostic (2.20e-1)" "unprognostic (2.26e-1)" 6.8 4.2 4.6 5.9 5.0 5.0 5.1 8.8 6.2 13.4 2.8 4.1 4.8 4.3 4.1 44.9 3.8 3.5 8.2 4.8 6.1 6.2 4.7 9.3 7.2 6.3 5.5 5.4 3.7 6.5 3.0 7.5 6.6 3.9 3.9 5.6 7.2 4.0 8.8 4.5 5.0 3.6 5.3 4.8 5.5 4.6 6.0 5.3 6.5 5.1 11.0 4.9 11.0 5.9 16.3 9.5 12.5 44.2 7.9 8.1 25.2 14.8 11.9 13.5 19.1 22.7 10.6 17.5 15.0 7.6 18.0 12.4 20.3 20.8 18.8 9.0 18.0 21.1 16.0 11.9 22.1 21.2 11.1 12.4 24.5 16.3 26.8 5.9 9.7 22.1 18.5 39.4 9.9 11.2 13.4 17.1 16.0 9.9 34.5 17.3 17.0 22.0 8.8 15.7 25.3 20.7 14.7 25.9 44.5 9.3 23.0 24.5 11.2 14.6 16.3 10.4 21.3 14.7 21.6 16.6 14.3 28.9 14.5 9.9 2.5 3.6 5.1 2.4 6.1 3.9 7.6 5.6 3.9 1.8 9.9 7.5 2.0 3.8 2.8 1.1 15.1 4.8 4.6 5.0 8.8 6.2 4.8 6.1 6.3 5.5 6.6 5.3 6.0 5.9 20.9 9.6 6.4 2.3 3.3 17.8 5.3 9.9 9.6 6.1 7.0 6.0 8.8 4.3 9.3 9.2 8.4 9.2 3.5 5.1 1.9 5.3 11.6 2.3 4.9 36.0 6.0 11.4 4.3 6.0 18.2 6.0 3.6 5.6 2.5 6.6 20.3 7.1 6.0 3.3 5.1 4.5 10.2 9.7 7.4 5.4 4.1 2.7 7.2 5.6 4.5 5.4 2.1 3.0 4.9 7.5 3.1 5.3 4.4 7.1 6.5 6.2 5.0 6.7 0.0 6.1 6.0 22.6 12.0 10.0 19.6 5.6 9.2 5.2 7.2 8.2 GRSF1 ENSG00000132463 "G-rich RNA sequence binding factor 1" Q12849 4 70815783-70839897 "Predicted intracellular proteins" "mRNA processing, tRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 275.2" "Cell type enhanced" "Detected in all" "monocytes: 301.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036984, HPA036985" Enhanced Enhanced Mitochondria NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 3: Monocytes - Immune response regulation" Mitochondria "HPA036984: AB_2675415, HPA036985: AB_10672785" "unprognostic (1.45e-3)" "unprognostic (1.82e-2)" "prognostic favorable (1.47e-5)" "unprognostic (8.63e-2)" "unprognostic (6.73e-2)" "unprognostic (4.15e-3)" "prognostic unfavorable (8.29e-5)" "unprognostic (1.94e-1)" "unprognostic (1.43e-1)" "unprognostic (1.66e-2)" "unprognostic (7.68e-2)" "unprognostic (8.05e-2)" "prognostic favorable (2.72e-9)" "unprognostic (6.12e-2)" "unprognostic (1.23e-1)" "unprognostic (1.78e-1)" "unprognostic (9.65e-3)" 38.0 61.2 38.4 36.9 37.7 23.7 37.7 42.5 47.1 36.3 58.9 54.6 43.1 32.5 34.0 42.0 43.0 35.2 80.7 41.0 44.5 55.8 54.4 35.5 47.4 40.3 42.3 38.4 62.0 48.8 21.5 43.8 41.6 39.9 62.7 25.4 83.9 35.3 275.2 32.0 41.3 40.0 40.7 34.6 50.8 32.8 40.9 76.0 45.7 155.0 53.7 50.3 25.8 46.1 116.9 78.1 90.0 94.5 93.5 108.1 128.3 138.2 87.3 102.3 83.5 80.5 117.1 167.6 102.9 143.7 53.0 43.4 161.3 108.6 135.9 91.3 52.8 88.4 75.2 112.4 115.1 130.8 48.7 91.9 102.2 103.6 71.6 123.0 106.9 91.9 102.6 94.7 144.2 124.9 217.4 92.0 96.3 127.1 80.9 88.2 139.8 71.6 126.1 144.0 93.4 84.0 65.3 183.6 234.3 104.7 79.8 63.3 98.4 95.1 99.7 79.4 88.7 78.1 66.2 106.4 78.6 83.6 94.5 12.7 17.4 7.7 10.1 12.3 12.2 7.4 14.6 15.5 28.1 6.1 14.4 12.6 2.0 20.0 15.2 27.2 13.3 8.4 38.4 37.7 42.5 47.1 41.0 44.5 40.3 42.3 41.6 40.7 40.9 46.1 27.8 32.1 36.6 19.6 38.0 50.0 53.7 32.9 48.3 18.2 37.7 28.3 135.5 40.0 30.4 27.6 25.0 106.2 57.4 52.9 74.3 70.3 7.6 53.8 40.4 33.0 69.0 41.2 35.1 61.3 141.3 41.2 65.2 44.5 17.2 60.2 35.0 50.9 63.2 28.6 30.5 73.5 36.7 66.3 53.7 6.7 34.8 45.4 62.2 24.4 301.5 23.8 41.2 21.6 28.0 60.1 46.7 39.1 58.7 65.9 47.1 74.1 27.6 19.6 19.7 38.4 46.2 35.0 61.8 69.7 50.4 77.2 45.1 99.0 89.3 67.0 GTPBP8 HSPC135 ENSG00000163607 "GTP binding protein 8 (putative)" Q8N3Z3 3 112990984-113015060 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 79.8;Spermatocytes: 79.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034831, HPA058631" Approved Enhanced Mitochondria No No "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 36: HEL - Hemostasis" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "HPA034831: AB_10671506, HPA058631: AB_2683783" "unprognostic (1.98e-1)" "unprognostic (1.02e-2)" "unprognostic (4.36e-2)" "unprognostic (1.99e-3)" "unprognostic (4.39e-2)" "unprognostic (2.00e-2)" "unprognostic (7.18e-3)" "unprognostic (1.80e-2)" "unprognostic (1.06e-2)" "unprognostic (2.08e-1)" "unprognostic (1.35e-2)" "unprognostic (1.21e-2)" "prognostic favorable (3.07e-5)" "unprognostic (7.10e-2)" "unprognostic (7.21e-2)" "unprognostic (4.57e-1)" "unprognostic (2.69e-1)" 5.3 5.7 3.6 6.1 4.3 8.4 5.6 4.6 4.9 4.6 4.6 6.0 6.6 5.6 3.7 7.4 4.4 5.2 11.9 3.9 3.9 7.3 5.9 4.3 11.2 4.3 3.8 6.7 6.8 8.9 4.5 6.1 4.2 5.7 7.1 4.2 6.5 3.7 20.0 4.8 6.0 5.5 4.4 4.9 7.5 14.4 3.9 9.7 10.1 18.3 8.1 5.9 4.7 6.4 25.5 10.8 15.7 16.5 9.2 15.6 11.5 17.9 14.7 17.0 20.5 18.6 10.4 16.8 9.7 10.0 14.2 17.1 21.0 17.1 23.5 7.0 13.4 46.5 11.4 11.6 8.4 28.9 10.5 11.9 11.9 9.6 7.0 19.2 16.1 19.9 16.4 19.5 18.0 8.8 18.5 14.4 32.8 13.2 20.8 16.1 14.7 10.4 14.4 16.3 17.5 18.2 14.2 11.3 25.7 13.7 12.3 19.6 9.8 12.7 19.4 4.5 16.0 13.1 17.4 24.0 12.7 23.6 14.0 7.9 4.3 2.9 6.4 3.0 5.7 4.2 7.8 6.3 8.1 3.6 9.9 6.5 0.7 8.7 2.7 3.7 5.4 4.5 3.6 4.3 4.6 4.9 3.9 3.9 4.3 3.8 4.2 4.4 3.9 6.4 13.1 16.0 15.4 2.9 16.9 13.5 15.9 28.8 8.0 11.5 12.9 12.4 25.8 10.0 19.5 5.5 6.2 28.3 27.1 10.4 23.5 16.3 79.8 17.7 12.9 11.6 10.2 22.7 5.5 18.3 25.1 13.3 12.8 18.3 19.7 20.0 17.9 7.7 22.7 10.1 6.3 10.3 28.5 16.7 14.8 35.5 11.8 13.6 10.6 4.7 18.3 10.4 13.4 7.1 6.9 16.5 12.2 5.7 17.1 12.8 17.7 29.6 16.0 14.0 0.0 17.4 15.8 79.7 28.1 16.1 12.1 15.2 22.5 34.9 12.0 18.9 HADHA "GBP, LCEH, LCHAD, MTPA" ENSG00000084754 "Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha" P40939 2 26190635-26244672 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Lyase, Multifunctional enzyme, Oxidoreductase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 502.5" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 527.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015536, HPA056070" Approved Enhanced Mitochondria NA NA 470000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" Mitochondria "HPA015536: AB_1850473, HPA056070: AB_2683026" "unprognostic (2.02e-1)" "unprognostic (1.38e-2)" "unprognostic (2.55e-1)" "unprognostic (3.43e-1)" "unprognostic (2.67e-2)" "unprognostic (3.23e-2)" "unprognostic (1.25e-2)" "unprognostic (2.02e-1)" "unprognostic (5.16e-2)" "unprognostic (3.45e-1)" "unprognostic (3.81e-1)" "unprognostic (1.16e-1)" "prognostic favorable (3.68e-5)" "unprognostic (7.97e-2)" "unprognostic (1.71e-1)" "unprognostic (2.87e-3)" "unprognostic (2.64e-2)" 105.0 125.3 57.7 31.1 60.7 46.3 94.9 65.0 69.6 72.6 59.1 108.4 115.0 61.8 30.7 90.1 60.1 32.4 330.2 52.8 61.9 99.0 156.7 66.9 35.3 64.4 62.2 77.8 101.4 95.0 57.4 39.2 64.2 60.2 76.1 14.9 77.9 33.4 502.5 95.7 106.2 57.4 61.8 68.4 93.8 49.0 62.4 46.7 59.5 300.7 58.5 79.1 73.6 67.2 105.7 88.1 58.4 90.8 221.1 139.9 51.5 80.6 84.7 78.5 67.7 114.7 104.1 71.7 50.2 138.4 78.6 66.8 103.4 152.6 72.5 139.1 103.6 103.3 86.2 197.9 73.3 132.2 69.2 142.7 101.6 112.4 109.3 82.8 127.7 70.4 140.2 133.2 101.1 128.2 63.4 137.7 50.1 77.5 134.1 52.9 128.5 143.7 90.3 125.3 41.9 85.1 94.6 104.6 102.4 44.5 52.2 125.8 127.1 48.8 70.7 69.9 58.0 44.8 86.5 113.4 77.6 150.2 56.2 22.5 84.0 33.5 31.8 92.3 39.1 40.5 36.8 38.7 80.8 31.2 42.6 40.1 20.9 38.8 86.1 31.3 50.9 89.9 57.7 60.7 65.0 69.6 52.8 61.9 64.4 62.2 64.2 61.8 62.4 67.2 122.4 89.8 99.0 47.0 101.2 89.0 137.5 139.9 97.3 35.6 89.7 96.4 349.9 82.9 128.0 77.3 52.1 182.0 95.1 242.1 131.0 120.8 39.2 73.3 121.1 99.1 91.4 155.9 22.8 108.5 94.7 96.1 100.4 85.5 139.9 140.3 84.3 185.1 163.0 20.2 28.2 156.5 89.5 136.8 106.0 74.3 92.6 145.0 81.8 12.2 170.7 65.4 93.7 30.7 37.4 90.0 195.6 84.2 90.4 76.2 527.4 182.5 84.8 62.3 52.6 129.9 109.6 147.9 54.9 136.5 103.3 129.2 100.5 154.7 216.7 104.4 HCCS "CCHL, MLS" ENSG00000004961 "Holocytochrome c synthase" P53701 X 11111301-11123086 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Lyase "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002946 Approved Enhanced Mitochondria "Intracellular and membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" Mitochondria "HPA002946: AB_1079041" "prognostic unfavorable (8.69e-5)" "unprognostic (6.89e-3)" "unprognostic (8.46e-3)" "unprognostic (4.92e-2)" "unprognostic (1.34e-1)" "unprognostic (5.44e-2)" "prognostic unfavorable (1.35e-5)" "unprognostic (9.18e-2)" "unprognostic (2.73e-1)" "unprognostic (2.52e-2)" "unprognostic (2.10e-2)" "unprognostic (1.60e-1)" "prognostic favorable (6.17e-8)" "unprognostic (2.66e-2)" "unprognostic (1.52e-1)" "unprognostic (2.04e-1)" "unprognostic (1.93e-2)" 13.9 16.1 6.2 13.7 6.7 20.5 12.6 7.0 8.4 8.4 8.4 21.6 23.1 9.6 7.6 19.3 8.5 10.8 39.0 7.4 6.8 17.6 22.9 11.5 15.6 6.7 6.2 8.3 9.9 25.1 8.3 13.1 6.4 9.5 21.6 13.5 15.2 10.0 64.4 17.6 20.2 12.5 6.2 14.5 15.3 10.2 6.7 13.0 10.8 57.0 17.1 22.3 11.6 6.1 54.3 60.5 31.8 28.5 25.6 25.2 29.2 52.0 43.0 67.8 57.5 70.7 38.5 34.3 26.3 46.1 80.8 49.8 63.2 51.8 70.5 30.8 48.0 34.1 80.8 38.6 47.3 40.9 39.4 24.2 37.4 67.9 46.5 37.9 49.1 26.1 63.1 41.1 46.3 72.5 28.0 31.4 51.5 36.6 70.1 27.3 59.9 65.4 44.0 44.8 20.9 24.2 54.8 58.7 38.2 66.7 45.6 27.1 48.7 42.4 23.6 110.4 47.0 26.9 29.0 47.8 35.5 28.8 42.7 25.6 47.8 30.1 20.2 66.4 19.0 39.0 19.6 18.2 62.2 34.7 17.1 22.1 13.1 19.1 57.4 56.2 23.5 19.0 6.2 6.7 7.0 8.4 7.4 6.8 6.7 6.2 6.4 6.2 6.7 6.1 15.5 6.4 4.8 2.3 20.8 54.8 53.2 57.0 22.8 5.3 16.1 13.7 49.3 17.2 33.3 16.5 0.0 32.9 12.4 44.6 50.9 34.9 13.7 19.0 10.4 21.0 10.8 32.8 3.8 29.3 37.9 17.1 12.8 16.7 13.3 10.4 15.7 18.5 41.8 8.4 4.5 19.2 67.1 21.0 44.1 2.3 13.4 23.5 24.9 1.9 27.9 13.0 7.2 2.0 2.7 68.4 31.9 10.5 18.4 63.5 46.4 36.0 28.9 7.1 6.6 12.5 20.1 24.4 28.4 21.8 46.0 40.9 12.0 15.6 30.2 88.6 HEATR1 "BAP28, FLJ10359, UTP10" ENSG00000119285 "HEAT repeat containing 1" Q9H583 1 236549005-236604516 "Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing, Transcription, Transcription regulation" Ribonucleoprotein "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046917, HPA062200" Approved Enhanced "Nucleoli fibrillar center,Mitochondria" NA NA 470000 "Cluster 37: B-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nucleoli fibrillar center" Mitochondria "HPA046917: AB_2679863, HPA062200: AB_2684709" "unprognostic (2.61e-1)" "unprognostic (1.44e-3)" "unprognostic (6.26e-2)" "unprognostic (1.34e-3)" "unprognostic (7.18e-2)" "unprognostic (4.98e-2)" "prognostic unfavorable (2.05e-4)" "unprognostic (5.82e-2)" "unprognostic (4.15e-2)" "unprognostic (3.80e-1)" "unprognostic (4.67e-3)" "unprognostic (1.10e-1)" "prognostic unfavorable (4.04e-4)" "unprognostic (8.08e-2)" "unprognostic (3.38e-1)" "unprognostic (3.27e-2)" "unprognostic (4.00e-2)" 8.5 5.6 3.3 11.1 4.1 12.7 9.8 4.6 4.0 6.8 3.3 6.2 5.6 8.7 6.5 7.3 7.0 5.5 4.4 3.5 3.7 5.4 5.5 5.2 12.9 3.7 3.3 9.4 8.7 7.9 3.4 7.7 3.8 6.2 7.5 4.8 6.2 6.4 6.6 10.4 6.2 8.0 3.7 8.5 6.2 14.4 4.2 10.1 7.9 5.7 13.5 10.8 6.7 6.5 35.2 41.4 21.2 32.3 29.1 32.5 47.4 27.7 17.8 31.2 27.7 41.8 29.0 57.3 30.4 25.8 19.3 41.5 48.7 29.7 42.0 29.0 56.0 40.7 28.3 36.1 26.1 73.5 25.2 26.7 26.2 47.2 40.5 14.9 36.3 25.9 93.8 18.8 31.5 18.8 35.1 20.1 84.9 44.8 16.9 38.6 30.6 53.8 19.9 34.9 19.9 44.1 33.5 23.7 28.3 14.1 28.2 27.2 34.7 31.2 29.5 40.6 69.4 35.4 47.2 65.5 27.8 40.2 47.4 1.6 3.3 1.0 6.0 4.2 5.6 9.1 5.9 6.6 4.0 6.5 8.1 7.8 0.4 5.7 4.2 5.2 5.3 2.3 3.3 4.1 4.6 4.0 3.5 3.7 3.7 3.3 3.8 3.7 4.2 6.5 13.3 3.2 12.8 19.6 21.8 19.8 16.3 8.3 26.2 12.4 9.8 7.6 4.2 7.2 11.7 5.5 18.8 8.1 15.0 3.6 3.9 8.9 10.5 8.4 26.3 12.4 4.2 12.6 35.1 8.5 10.8 15.2 8.6 11.3 32.9 23.4 10.4 9.7 7.5 6.7 30.4 6.2 4.1 11.3 7.5 2.7 14.0 11.7 1.8 26.2 9.6 3.0 9.2 36.2 34.1 12.0 4.3 10.1 19.0 15.7 3.3 5.6 11.5 9.6 0.0 19.4 11.8 29.3 30.1 19.3 16.9 4.9 18.1 15.6 11.1 12.0 HIBCH ENSG00000198130 "3-hydroxyisobutyryl-CoA hydrolase" Q6NVY1 2 190189735-190344193 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Branched-chain amino acid catabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 230.2;Proximal tubular cells: 376.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036540, HPA036541, HPA067080" Enhanced Enhanced Mitochondria NA NA 74000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 7: Kidney - Transmembrane transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA036540: AB_10673355, HPA036541: AB_2675182, HPA067080: " "unprognostic (3.60e-3)" "unprognostic (3.88e-2)" "unprognostic (6.81e-2)" "unprognostic (2.36e-3)" "unprognostic (3.38e-1)" "unprognostic (2.78e-3)" "unprognostic (1.96e-1)" "unprognostic (1.89e-1)" "unprognostic (2.88e-1)" "prognostic favorable (1.22e-4)" "unprognostic (7.32e-2)" "unprognostic (1.37e-2)" "prognostic favorable (1.04e-10)" "unprognostic (1.34e-1)" "unprognostic (3.73e-1)" "unprognostic (1.36e-1)" "unprognostic (4.18e-3)" 34.0 60.1 40.6 17.4 49.2 14.5 28.5 40.5 60.3 33.4 51.0 37.5 55.9 28.1 29.1 34.9 22.5 22.3 28.7 40.7 47.7 142.2 129.0 13.9 20.5 43.9 43.1 18.6 27.2 58.2 19.1 18.6 44.9 25.5 40.9 38.4 20.9 23.2 49.2 58.7 33.9 18.3 45.0 17.8 25.6 21.7 43.3 16.8 31.7 38.5 21.9 23.7 26.6 72.6 23.5 16.1 37.0 23.8 29.9 27.6 16.9 23.1 11.4 20.8 22.1 46.8 20.2 33.3 36.1 18.1 17.0 44.4 33.2 30.7 29.5 47.0 25.1 44.5 37.7 41.4 10.7 31.8 16.7 19.8 17.8 24.3 4.8 32.3 31.6 30.4 55.2 30.3 20.8 18.2 34.3 33.6 11.1 30.2 30.2 42.4 24.8 83.8 43.8 68.4 27.9 24.0 18.0 27.2 66.8 47.2 32.0 21.3 26.5 22.8 20.8 16.1 15.8 18.7 45.2 30.9 20.7 27.4 18.6 27.8 11.9 26.4 19.5 14.2 21.3 43.5 21.8 21.0 20.9 34.7 22.9 29.6 6.0 32.0 11.3 26.7 37.0 12.7 40.6 49.2 40.5 60.3 40.7 47.7 43.9 43.1 44.9 45.0 43.3 72.6 23.3 22.4 25.8 129.3 29.8 56.0 131.4 74.9 34.1 35.3 39.1 24.1 28.6 42.9 51.3 36.8 102.2 53.6 18.8 53.5 115.4 27.4 230.2 48.0 21.4 33.3 37.8 13.0 46.4 29.4 22.3 27.7 29.6 39.3 10.2 41.1 89.3 117.4 35.3 25.2 51.5 31.4 71.2 15.7 11.7 62.9 34.8 15.9 46.2 52.5 14.1 35.5 39.1 104.0 141.1 15.6 26.6 45.5 23.3 27.9 32.4 376.2 47.6 50.5 39.5 29.9 26.2 18.0 29.4 45.5 40.6 20.0 30.7 61.7 62.7 67.8 HINT2 ENSG00000137133 "Histidine triad nucleotide binding protein 2" Q9BX68 9 35812960-35815354 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 633.9;Hepatocytes: 457.4;Proximal tubular cells: 578.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020961, HPA059109" Supported Enhanced Mitochondria "Intracellular and membrane" NA NA 110000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA020961: AB_1850715, HPA059109: AB_2683906" "unprognostic (9.64e-3)" "unprognostic (1.53e-2)" "unprognostic (3.02e-1)" "unprognostic (3.01e-2)" "unprognostic (5.51e-2)" "unprognostic (3.97e-2)" "unprognostic (1.07e-1)" "unprognostic (2.38e-2)" "unprognostic (2.61e-1)" "prognostic favorable (1.66e-4)" "unprognostic (3.71e-3)" "unprognostic (2.87e-2)" "prognostic favorable (2.97e-9)" "unprognostic (4.29e-2)" "unprognostic (1.41e-1)" "unprognostic (8.78e-2)" "unprognostic (1.72e-1)" 50.8 79.5 41.7 15.5 43.9 27.0 48.5 44.9 46.8 23.2 40.3 42.6 34.9 25.9 48.6 27.5 29.9 14.9 87.4 39.8 43.1 91.1 169.2 30.2 21.0 43.8 42.5 19.2 65.9 72.6 41.2 17.6 42.0 33.9 34.2 20.4 39.7 26.1 80.1 33.4 34.2 20.1 43.9 33.8 56.9 29.8 47.3 38.8 38.4 85.5 23.8 30.6 24.2 44.0 30.3 76.1 47.1 45.6 29.0 24.3 33.2 27.8 39.2 42.3 46.1 49.9 31.1 39.9 31.7 25.3 59.8 29.3 21.2 40.9 44.1 87.8 40.7 42.2 64.1 45.8 68.1 25.1 40.0 27.3 36.8 40.2 64.8 16.7 33.2 91.4 25.5 117.4 34.0 60.3 61.3 31.3 21.4 70.0 138.7 60.8 33.1 53.6 61.5 21.5 38.4 46.4 36.0 42.7 49.6 27.5 45.9 44.6 16.5 22.0 37.7 30.4 35.7 107.0 127.3 57.4 49.8 32.2 36.2 41.0 77.5 4.7 68.9 58.5 62.4 98.9 73.7 69.8 113.4 96.7 56.4 58.6 7.6 66.8 56.9 246.1 107.3 81.2 41.7 43.9 44.9 46.8 39.8 43.1 43.8 42.5 42.0 43.9 47.3 44.0 49.3 22.4 17.5 5.2 57.9 45.4 63.4 137.6 49.5 39.8 99.1 105.8 115.1 130.1 68.3 80.9 20.9 154.9 69.3 148.2 633.9 115.5 67.3 83.9 28.6 47.8 96.0 100.8 1.7 172.1 71.7 53.2 52.5 44.6 18.4 43.5 63.1 457.4 113.9 20.2 2.5 127.4 126.1 61.1 51.4 128.0 40.4 47.7 120.9 1.9 74.1 123.7 87.6 1.5 4.5 85.6 157.5 44.8 77.7 40.7 181.4 578.1 105.1 45.5 46.0 54.2 72.6 38.4 77.4 64.7 45.9 56.8 51.0 85.1 126.7 84.8 HKDC1 "FLJ22761, FLJ37767" ENSG00000156510 "Hexokinase domain containing 1" Q2TB90 10 69220332-69267552 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Glycolysis "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 53.5;retina: 46.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 31.5;Distal enterocytes: 29.0;Ductal cells: 32.6;Endometrial ciliated cells: 50.0;Glandular and luminal cells: 55.2;Muller glia cells: 126.9;Proximal enterocytes: 56.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 20.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory CD4 T-cell: 3.1;naive CD4 T-cell: 5.8;naive CD8 T-cell: 2.3;T-reg: 5.4" "Lineage enriched" "Detected in single" 23 "T-cells: 5.8" "Cell line enhanced" "Detected in some" "A549: 40.1;CACO-2: 57.5;CAPAN-2: 111.4;EFO-21: 33.9;GAMG: 45.4;Hep G2: 33.6;RPTEC TERT1: 81.9" "Region enhanced" "Detected in many" "cerebral cortex: 11.9" "Low region specificity" "Detected in all" "HPA064198, HPA064230" Enhanced Enhanced Mitochondria No No "Cluster 20: T-cells - T-cell receptor" "Cluster 56: Intestine - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 5: Muller glia cells - Visual perception" Mitochondria "HPA064198: AB_2685210, HPA064230: AB_2685219" "unprognostic (1.29e-2)" "unprognostic (2.26e-2)" "unprognostic (1.86e-1)" "unprognostic (8.47e-2)" "unprognostic (1.55e-1)" "unprognostic (3.05e-1)" "unprognostic (6.31e-3)" "unprognostic (5.03e-2)" "unprognostic (1.08e-1)" "unprognostic (1.19e-1)" "unprognostic (1.23e-3)" "unprognostic (3.11e-1)" "unprognostic (1.04e-3)" "unprognostic (1.35e-1)" "unprognostic (2.24e-1)" "unprognostic (2.10e-3)" "unprognostic (2.19e-1)" 0.1 0.0 1.1 2.7 1.3 0.0 0.0 1.4 1.0 1.1 1.4 6.8 53.5 0.9 0.0 0.1 4.6 6.8 0.0 1.0 1.1 13.3 4.6 1.5 1.0 1.3 2.1 0.0 6.2 0.0 0.3 0.0 1.7 0.0 4.2 46.8 0.1 0.0 0.0 0.1 48.0 0.5 1.4 0.3 1.1 1.0 1.0 5.2 9.3 0.0 0.2 0.0 0.1 1.2 1.2 40.1 0.2 0.1 0.0 0.0 0.2 0.0 0.3 0.1 0.1 57.5 111.4 0.0 33.9 0.3 45.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 33.6 2.7 0.0 0.0 0.0 0.3 0.4 3.2 0.6 0.0 11.3 0.0 0.0 0.7 0.1 0.2 0.1 0.0 11.9 1.3 0.0 1.2 0.1 81.9 0.1 0.0 0.0 0.0 0.0 1.3 0.3 0.0 0.0 0.0 0.4 1.6 0.2 0.8 0.0 0.1 0.0 8.1 0.0 0.5 0.0 0.0 0.0 0.6 0.0 0.5 0.0 3.1 1.0 0.0 0.0 5.8 2.3 0.0 0.2 0.0 0.0 5.4 1.0 1.1 1.3 1.4 1.0 1.0 1.1 1.3 2.1 1.7 1.4 1.0 1.2 0.0 3.2 4.8 11.8 0.7 0.0 0.0 0.3 0.0 1.9 0.0 0.0 1.0 31.5 1.0 16.5 0.0 0.0 0.2 29.0 1.9 32.6 0.6 50.0 4.5 0.5 0.0 0.0 0.4 7.3 0.0 0.2 1.5 55.2 0.0 0.0 0.0 0.4 0.1 3.3 0.5 5.6 0.0 0.3 0.0 0.2 0.3 0.4 0.0 0.0 0.0 126.9 0.0 0.0 0.5 25.5 12.7 0.0 0.3 0.0 56.3 15.7 0.3 5.1 0.0 0.1 0.4 0.0 0.2 0.0 0.0 0.0 1.3 0.1 5.6 0.3 HSDL2 "C9orf99, SDR13C1" ENSG00000119471 "Hydroxysteroid dehydrogenase like 2" Q6YN16 9 112380080-112472405 "Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 181.3" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 214.8;Early spermatids: 153.9;Granulosa cells: 187.2;Late spermatids: 163.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Lineage enriched" "Detected in all" 5 "granulocytes: 54.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042890, HPA050453" Enhanced Enhanced Mitochondria NA NA "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "HPA042890: AB_2678216, HPA050453: AB_2681131" "unprognostic (3.17e-3)" "unprognostic (1.62e-2)" "unprognostic (1.90e-3)" "prognostic favorable (9.23e-6)" "unprognostic (3.94e-2)" "unprognostic (1.43e-2)" "unprognostic (1.17e-1)" "unprognostic (5.15e-2)" "unprognostic (7.58e-2)" "unprognostic (6.48e-2)" "unprognostic (1.57e-1)" "unprognostic (1.82e-1)" "prognostic favorable (9.29e-7)" "unprognostic (1.44e-1)" "unprognostic (2.33e-1)" "unprognostic (1.35e-2)" "unprognostic (7.35e-2)" 76.3 63.6 28.1 13.3 30.1 11.6 22.8 25.1 29.5 23.3 27.6 31.7 38.9 22.8 11.5 29.8 21.2 19.0 89.9 24.8 33.1 69.0 149.0 28.7 13.9 25.4 33.2 50.8 20.0 21.8 8.8 16.8 27.1 20.3 26.9 12.6 18.8 15.9 151.7 31.1 32.2 20.5 26.6 18.6 24.6 14.0 32.0 19.6 30.4 181.3 15.8 29.2 15.0 28.5 45.0 39.4 29.0 14.8 49.0 48.4 33.4 30.1 18.6 21.1 17.7 77.0 49.4 28.5 16.2 44.4 26.9 50.6 31.9 42.2 25.8 120.9 21.0 30.0 58.5 76.1 30.7 17.1 18.5 52.0 29.9 31.3 22.8 30.5 24.8 34.7 42.3 18.9 58.2 29.6 42.5 15.3 17.2 106.9 50.3 27.1 87.4 42.7 44.5 40.4 20.7 14.5 75.8 49.5 26.0 23.7 70.0 20.0 28.3 30.2 27.9 85.2 29.6 21.5 57.3 13.5 37.0 24.8 18.2 54.3 8.4 32.8 4.6 8.1 6.8 6.9 4.8 5.0 9.5 8.4 5.6 5.9 48.0 5.9 11.5 9.4 8.7 4.9 28.1 30.1 25.1 29.5 24.8 33.1 25.4 33.2 27.1 26.6 32.0 28.5 32.0 99.3 84.3 48.6 14.1 13.3 17.5 21.6 29.6 9.3 12.0 13.3 214.8 14.3 32.2 14.7 6.2 26.5 18.3 23.7 64.6 15.5 153.9 38.6 38.3 19.1 14.9 32.8 10.8 18.7 30.9 31.1 29.0 27.8 30.4 187.2 17.2 124.2 35.7 6.7 12.2 32.2 8.2 23.6 12.5 163.0 27.4 27.5 8.8 15.9 47.3 24.1 6.2 16.1 19.3 13.2 23.5 47.0 20.9 16.0 52.4 111.1 37.7 14.5 46.0 18.1 46.9 12.9 16.4 34.2 16.2 31.7 16.2 108.9 36.2 29.5 HSPD1 "GroEL, HSP60, SPG13" ENSG00000144381 "Heat shock protein family D (Hsp60) member 1" P10809 2 197486584-197516737 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction" "Chaperone, Isomerase" "Cancer-related genes, Disease variant, Hereditary spastic paraplegia, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 790.6" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 1737.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001523, CAB002775, HPA050025, CAB072816" Supported Enhanced Mitochondria NA NA 18000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 35: Non-specific - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" Mitochondria "CAB002775: , CAB072816: , HPA001523: AB_1079028, HPA050025: AB_2680995" "unprognostic (2.79e-2)" "unprognostic (1.72e-2)" "unprognostic (5.21e-2)" "prognostic unfavorable (1.61e-4)" "unprognostic (2.59e-1)" "unprognostic (3.57e-3)" "prognostic unfavorable (2.25e-4)" "unprognostic (3.51e-2)" "unprognostic (9.91e-2)" "unprognostic (8.63e-3)" "unprognostic (3.47e-2)" "unprognostic (7.83e-3)" "unprognostic (5.64e-3)" "unprognostic (1.73e-2)" "unprognostic (1.52e-1)" "unprognostic (2.61e-2)" "unprognostic (4.10e-2)" 179.4 790.6 188.6 128.3 191.6 110.6 168.8 204.9 401.9 96.9 217.8 170.0 158.1 90.8 89.3 124.5 132.6 69.1 145.0 184.3 198.6 374.9 462.6 136.6 149.2 199.6 198.5 167.6 219.0 159.2 116.0 148.6 205.3 104.5 195.1 71.8 93.9 93.6 162.7 83.3 148.7 104.5 195.1 94.6 155.4 57.6 198.6 99.3 138.7 176.7 172.7 144.6 92.3 201.4 559.7 650.1 541.3 496.9 373.6 389.2 786.5 573.2 304.7 686.1 495.6 2219.1 326.2 1724.4 730.0 304.1 834.2 538.4 2232.9 633.2 943.0 417.0 888.2 1209.8 984.8 2562.8 353.2 1331.4 349.1 445.5 717.1 599.5 1053.2 471.4 542.6 919.1 1535.3 606.8 501.7 690.4 853.6 1304.2 1086.4 735.2 1424.9 1000.1 679.7 1235.5 709.5 539.7 716.5 400.8 582.0 608.5 771.0 1116.3 425.0 789.4 242.2 405.8 570.4 532.8 910.0 331.1 861.4 1399.5 485.7 795.3 456.7 12.1 52.3 11.4 36.4 81.8 71.7 63.8 59.6 54.3 84.6 54.0 81.0 70.3 11.0 62.6 72.1 49.4 51.8 70.6 188.6 191.6 204.9 401.9 184.3 198.6 199.6 198.5 205.3 195.1 198.6 201.4 216.4 166.7 172.5 38.8 220.4 246.6 1737.2 247.5 264.0 75.8 216.0 263.1 239.2 195.9 287.9 79.1 256.5 825.7 197.7 213.7 375.6 235.0 6.2 322.2 304.5 233.9 274.6 241.6 31.9 145.9 419.8 356.0 215.6 445.2 299.5 407.1 63.1 312.5 328.0 95.9 47.2 302.2 166.8 88.6 479.3 12.8 130.5 381.9 163.7 30.0 138.5 125.7 68.0 20.6 35.6 171.4 163.2 113.6 322.9 705.9 160.1 797.1 328.6 117.1 85.5 199.0 471.7 88.5 106.0 262.4 207.1 1001.2 467.2 1017.4 512.1 861.5 IARS2 FLJ10326 ENSG00000067704 "Isoleucyl-tRNA synthetase 2, mitochondrial" Q9NSE4 1 220094132-220148041 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Cataract, Deafness, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024212, HPA024594, HPA024596" Enhanced Enhanced Mitochondria NA NA 35000 "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA024212: AB_1851363, HPA024594: AB_1851368, HPA024596: AB_1851370" "unprognostic (2.15e-2)" "prognostic unfavorable (1.04e-4)" "unprognostic (2.42e-3)" "unprognostic (3.22e-2)" "unprognostic (2.04e-1)" "unprognostic (1.55e-1)" "unprognostic (1.91e-1)" "unprognostic (7.81e-2)" "unprognostic (1.78e-1)" "unprognostic (1.91e-1)" "prognostic unfavorable (9.24e-5)" "unprognostic (9.48e-2)" "unprognostic (2.10e-2)" "unprognostic (3.01e-1)" "unprognostic (2.16e-1)" "unprognostic (8.87e-2)" "unprognostic (6.27e-3)" 55.8 49.8 19.9 33.3 21.1 18.3 41.8 23.5 25.4 35.3 37.8 54.2 43.4 31.8 31.4 47.9 41.4 30.5 60.0 20.0 21.8 65.5 83.8 31.0 38.8 22.7 22.2 39.0 33.6 80.5 16.0 40.7 25.0 36.1 54.8 34.8 40.0 37.5 92.9 40.5 40.4 39.4 21.6 28.4 39.1 30.1 22.3 31.8 39.7 85.7 43.1 35.6 30.0 22.9 137.2 125.6 70.7 69.9 104.2 104.4 169.6 81.4 86.9 87.9 70.7 121.7 138.8 125.6 107.1 101.4 68.0 129.3 99.0 101.5 100.9 87.5 119.3 62.6 94.6 137.8 64.6 100.4 64.9 76.0 101.3 95.4 97.6 84.7 86.9 79.9 156.9 70.7 116.7 75.9 79.8 72.0 92.1 106.2 82.1 69.5 140.7 202.2 126.2 90.4 38.0 106.6 123.2 188.2 130.3 80.6 218.5 111.9 89.8 86.1 71.6 117.0 138.4 60.0 98.9 90.8 91.3 77.3 97.6 33.8 24.6 22.8 23.0 27.7 30.8 23.6 24.9 30.3 29.2 18.3 27.8 25.6 4.7 28.3 22.3 10.6 29.9 26.7 19.9 21.1 23.5 25.4 20.0 21.8 22.7 22.2 25.0 21.6 22.3 22.9 66.4 35.3 38.0 15.7 30.7 20.1 28.6 44.1 34.7 28.6 40.1 39.4 144.3 22.8 42.9 29.5 25.0 79.0 31.5 54.2 11.7 47.7 20.0 63.8 48.3 43.7 36.2 29.6 17.3 65.4 55.5 37.0 32.1 44.3 19.6 41.3 37.5 99.6 45.9 20.2 22.7 55.4 28.5 51.0 11.2 6.8 37.3 35.9 19.6 15.0 46.1 34.6 27.8 16.6 31.5 67.4 44.9 42.5 33.1 34.1 38.4 36.1 62.0 35.5 46.0 46.3 39.0 44.6 44.1 63.5 26.6 71.7 31.0 54.4 69.9 27.6 IDH3A ENSG00000166411 "Isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha" P50213 15 78131498-78171945 "Citric acid cycle related proteins, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 99.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 144.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041465, HPA062971" Supported Enhanced Mitochondria No No 110000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA041465: AB_10794377, HPA062971: AB_2684913" "unprognostic (2.33e-1)" "unprognostic (1.21e-1)" "unprognostic (5.76e-3)" "unprognostic (2.26e-1)" "unprognostic (1.02e-1)" "unprognostic (4.01e-1)" "unprognostic (2.29e-1)" "unprognostic (6.47e-2)" "unprognostic (1.69e-2)" "unprognostic (2.30e-1)" "unprognostic (3.05e-1)" "unprognostic (1.42e-1)" "prognostic favorable (6.49e-8)" "unprognostic (1.40e-1)" "unprognostic (3.08e-2)" "unprognostic (4.49e-2)" "unprognostic (3.39e-2)" 22.6 25.1 11.5 19.9 12.6 9.7 9.6 17.0 14.7 12.4 21.4 26.2 36.6 13.7 7.8 17.0 11.0 9.0 62.5 14.8 13.2 16.8 14.2 11.9 17.1 13.0 13.1 10.8 13.0 54.7 6.9 12.1 15.2 13.9 26.7 26.2 16.2 16.1 79.4 15.8 36.0 17.1 10.1 15.3 11.9 16.9 14.3 35.0 11.2 99.7 24.8 17.7 11.1 14.8 43.8 58.5 10.4 36.5 25.5 26.1 22.6 50.8 24.5 40.6 30.5 41.6 25.8 91.6 36.8 29.9 59.9 64.2 98.2 39.3 37.0 40.7 32.2 35.7 62.4 19.2 21.8 69.8 48.8 19.9 23.6 39.4 41.2 19.3 25.7 32.0 46.4 35.9 26.0 41.4 51.4 17.4 12.9 25.2 21.8 29.3 44.4 28.1 33.4 58.3 41.4 15.8 58.2 82.1 47.1 19.1 32.7 37.4 26.4 47.6 43.9 63.1 83.1 41.5 99.9 48.8 33.2 64.9 37.7 16.9 27.9 8.3 15.1 52.9 16.4 27.7 14.7 13.5 43.5 32.6 15.2 16.4 15.5 17.3 54.8 144.4 17.7 23.2 11.5 12.6 17.0 14.7 14.8 13.2 13.0 13.1 15.2 10.1 14.3 14.8 18.0 9.6 16.5 22.9 30.6 56.0 58.7 51.4 33.0 35.1 10.9 12.6 17.5 14.3 22.6 25.8 37.5 38.3 63.0 69.0 82.2 26.1 52.2 19.9 13.4 17.5 19.2 9.4 45.9 17.9 40.4 21.2 11.7 9.2 27.3 14.5 10.8 22.4 26.5 26.9 53.3 37.6 69.2 24.9 28.6 23.4 20.8 26.4 26.6 12.2 16.0 29.3 12.3 19.6 17.9 21.5 37.9 23.7 33.2 40.6 49.6 48.1 38.2 34.6 13.1 23.8 25.5 45.7 26.2 28.4 41.2 68.4 17.7 37.2 56.0 42.0 IDH3B RP46 ENSG00000101365 "Isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta" O43837 20 2658395-2664219 "Citric acid cycle related proteins, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049387, HPA054180" Supported Enhanced Mitochondria NA NA 8300 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA049387: AB_2680740, HPA054180: AB_2682407" "unprognostic (1.19e-1)" "unprognostic (1.47e-1)" "unprognostic (2.12e-1)" "unprognostic (2.43e-2)" "unprognostic (3.24e-2)" "unprognostic (6.83e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (2.76e-2)" "unprognostic (2.99e-1)" "unprognostic (5.69e-2)" "unprognostic (4.75e-3)" "unprognostic (1.39e-2)" "prognostic favorable (6.78e-8)" "unprognostic (8.89e-2)" "unprognostic (4.02e-2)" "unprognostic (2.79e-1)" "unprognostic (1.16e-1)" 55.6 61.3 51.8 33.4 53.0 57.9 54.7 60.8 57.9 56.6 49.4 70.8 73.9 57.3 35.9 62.4 49.8 29.6 185.8 53.8 56.3 71.0 60.5 43.9 41.9 58.0 54.0 57.7 46.0 75.3 36.8 41.1 60.0 45.7 59.7 46.1 49.1 43.1 204.0 61.9 59.9 44.7 50.6 53.1 63.7 36.6 56.6 59.5 49.4 236.6 56.5 55.5 53.4 56.0 111.6 147.4 66.0 57.9 71.3 55.9 76.0 58.2 74.0 134.5 106.7 191.4 113.4 124.5 52.2 80.4 123.7 152.7 122.9 189.0 122.6 34.7 96.7 151.2 58.4 200.6 69.7 166.5 31.8 74.4 71.5 125.9 65.7 59.2 80.4 105.6 194.9 67.7 83.0 61.1 146.1 190.4 128.3 113.4 137.9 117.7 120.2 140.2 77.7 102.5 118.5 85.5 71.9 235.0 127.3 50.8 118.1 73.0 72.4 104.2 65.4 35.8 136.3 91.2 225.3 129.8 49.1 169.9 101.2 76.0 111.7 72.2 84.9 120.8 64.5 96.3 72.8 77.7 131.9 84.6 84.6 73.1 31.4 84.8 110.9 61.2 108.1 102.1 51.8 53.0 60.8 57.9 53.8 56.3 58.0 54.0 60.0 50.6 56.6 56.0 50.7 38.5 28.2 10.4 52.1 56.7 60.2 103.8 48.9 37.9 38.5 38.2 186.0 52.9 49.5 23.9 33.3 133.9 71.3 81.7 156.5 88.5 59.3 28.2 36.0 53.7 50.7 41.6 7.0 102.1 86.3 49.2 37.2 35.9 48.2 54.1 41.7 55.4 97.6 13.5 7.6 68.4 71.2 57.7 60.9 115.1 45.1 51.7 69.4 10.3 78.7 49.3 56.7 6.6 8.9 70.8 72.5 47.4 38.1 37.5 121.7 174.9 33.4 33.4 78.9 50.0 64.1 52.8 55.3 48.4 60.0 108.5 49.1 63.4 113.7 54.3 IMMP1L "FLJ25059, IMMP1" ENSG00000148950 "Inner mitochondrial membrane peptidase subunit 1" Q96LU5 11 31432401-31509645 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038372, HPA058308" Approved Enhanced Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA038372: AB_10669643, HPA058308: AB_2732620" "unprognostic (2.39e-1)" "unprognostic (1.20e-2)" "unprognostic (1.12e-1)" "unprognostic (6.17e-2)" "unprognostic (9.67e-2)" "unprognostic (2.08e-2)" "prognostic unfavorable (7.97e-4)" "unprognostic (7.59e-2)" "unprognostic (4.66e-3)" "unprognostic (5.15e-3)" "prognostic favorable (6.72e-4)" "unprognostic (1.97e-1)" "unprognostic (1.07e-2)" "unprognostic (4.66e-1)" "unprognostic (4.52e-2)" "unprognostic (1.37e-2)" "unprognostic (1.04e-3)" 11.7 15.6 42.8 6.4 43.7 11.1 19.3 45.5 66.4 13.5 41.8 12.7 8.6 11.5 29.8 11.7 10.4 5.1 26.2 42.8 42.3 27.2 18.6 8.9 9.5 42.4 42.0 17.5 16.4 17.9 23.3 6.9 42.3 14.3 10.0 37.7 11.8 14.1 50.0 12.5 9.5 10.7 42.9 10.8 15.1 16.7 43.0 24.8 13.2 42.1 13.1 10.9 12.6 43.5 22.9 26.9 95.6 21.0 14.9 9.9 15.3 19.9 8.7 16.2 11.7 21.0 17.5 20.7 18.7 15.9 32.5 25.8 37.6 28.8 23.8 24.9 52.6 29.4 45.5 32.3 15.8 29.6 19.9 8.0 27.1 8.7 19.2 29.5 17.5 48.8 38.0 23.2 15.9 28.2 48.5 48.9 15.8 114.6 26.3 41.1 72.2 20.6 54.6 26.2 22.5 27.0 32.5 11.6 32.5 61.9 37.1 35.1 2.6 15.3 27.2 16.2 42.2 17.2 58.2 47.5 24.9 24.9 18.5 21.9 3.0 32.2 28.9 3.4 26.3 34.1 25.3 29.5 8.1 32.1 32.0 39.8 0.8 37.3 3.0 40.2 35.4 13.6 42.8 43.7 45.5 66.4 42.8 42.3 42.4 42.0 42.3 42.9 43.0 43.5 29.2 35.3 14.6 30.7 22.4 18.2 26.8 60.5 12.0 30.6 44.6 55.1 56.8 18.6 26.8 60.7 33.3 36.3 17.6 21.7 119.3 17.0 39.8 30.2 16.9 19.4 56.5 47.4 40.6 24.5 32.5 19.7 20.9 33.8 22.7 22.7 18.2 45.0 21.3 43.7 48.0 30.6 52.9 7.7 11.4 10.5 13.4 9.4 8.8 24.4 10.3 85.3 30.9 51.3 60.7 15.8 26.7 20.7 22.0 26.0 18.6 98.4 28.9 38.5 32.9 19.1 51.0 61.6 23.0 19.6 27.3 23.7 24.2 16.2 34.7 26.2 IMMT "HMP, Mic60, MICOS60, MINOS2, P87, P89" ENSG00000132305 "Inner membrane mitochondrial protein" Q16891 2 86143932-86195472 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 288.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 223.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022439, HPA036164, HPA036165" Supported Enhanced Mitochondria NA NA 220000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB022439: , HPA036164: AB_2674979, HPA036165: AB_2674980" "unprognostic (3.83e-3)" "unprognostic (1.56e-1)" "unprognostic (1.95e-2)" "prognostic unfavorable (1.06e-4)" "unprognostic (1.40e-1)" "unprognostic (2.45e-2)" "prognostic unfavorable (2.03e-4)" "unprognostic (5.66e-2)" "unprognostic (1.53e-1)" "unprognostic (8.10e-2)" "unprognostic (7.35e-2)" "unprognostic (2.21e-1)" "prognostic favorable (3.51e-6)" "unprognostic (2.06e-3)" "unprognostic (6.35e-2)" "unprognostic (1.20e-1)" "unprognostic (2.82e-1)" 41.3 82.4 30.3 34.9 31.8 40.3 36.5 33.1 39.0 30.2 41.9 57.4 57.4 35.0 27.6 43.4 30.9 27.1 174.8 31.9 34.5 80.9 65.0 32.5 44.3 35.3 34.2 28.1 48.5 90.2 36.0 36.7 35.1 29.4 58.1 42.4 37.9 35.1 200.9 38.0 46.6 38.9 29.8 44.8 56.0 49.2 32.6 52.3 35.5 288.9 47.1 41.5 33.8 32.8 115.6 111.2 99.2 45.6 93.7 88.3 101.5 80.5 85.6 108.0 98.7 160.7 89.1 175.7 78.9 87.7 87.7 83.4 128.9 118.4 131.8 71.4 105.9 139.0 65.6 192.0 95.7 135.9 91.1 100.6 84.0 101.7 119.5 67.2 124.7 99.7 138.4 96.7 105.1 99.0 135.6 140.8 117.8 175.1 88.2 89.9 211.2 158.7 122.5 128.3 119.3 89.0 82.9 124.0 126.3 77.4 70.7 94.6 93.6 76.0 83.6 112.0 101.8 76.6 104.1 119.9 86.9 158.8 94.4 12.1 29.2 12.2 23.5 34.0 20.7 15.9 20.6 19.3 32.9 13.7 18.3 22.3 3.8 20.8 33.2 17.2 23.2 25.4 30.3 31.8 33.1 39.0 31.9 34.5 35.3 34.2 35.1 29.8 32.6 32.8 29.3 54.5 49.2 31.3 42.1 23.3 34.9 51.6 30.1 40.9 21.6 19.7 223.0 24.3 57.3 40.5 33.3 94.9 49.6 57.9 133.1 59.9 152.4 26.5 34.0 38.3 56.0 76.1 41.6 52.8 73.9 36.3 39.8 26.8 48.0 55.6 35.7 64.2 70.9 23.5 46.5 46.2 38.7 49.4 28.3 158.9 27.7 48.9 17.8 26.2 80.6 30.2 52.5 29.1 44.1 43.3 36.3 36.9 56.4 28.6 59.8 92.6 41.8 42.5 6.6 39.7 58.2 100.7 54.6 41.1 24.9 98.5 45.6 118.6 68.0 33.6 L2HGDH "C14orf160, FLJ12618" ENSG00000087299 "L-2-hydroxyglutarate dehydrogenase" Q9H9P8 14 50237563-50312229 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 56.3;Excitatory neurons: 60.5;Inhibitory neurons: 61.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065409, HPA069708" Approved Enhanced Mitochondria NA NA "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 36: HEL - Hemostasis" "Cluster 9: Photoreceptor cells - Phototransduction" Mitochondria "HPA065409: AB_2685485, HPA069708: AB_2686179" "unprognostic (1.74e-1)" "unprognostic (1.15e-2)" "unprognostic (1.13e-2)" "unprognostic (1.23e-3)" "unprognostic (1.04e-2)" "unprognostic (4.33e-2)" "unprognostic (8.84e-2)" "unprognostic (1.58e-2)" "unprognostic (4.17e-2)" "unprognostic (9.91e-2)" "unprognostic (2.84e-1)" "unprognostic (1.97e-1)" "prognostic favorable (9.75e-10)" "unprognostic (1.24e-2)" "unprognostic (5.88e-2)" "unprognostic (1.45e-1)" "unprognostic (1.02e-2)" 4.6 2.5 2.9 2.2 2.9 2.7 3.7 6.1 5.5 2.3 1.3 4.3 4.7 2.4 3.0 5.1 3.1 2.0 5.2 2.7 2.5 19.6 12.6 1.8 2.6 1.2 2.4 2.5 3.9 6.1 2.3 1.7 1.1 3.3 5.0 11.4 2.8 3.2 15.5 5.1 3.6 2.5 1.2 1.3 4.3 3.9 2.4 3.0 4.8 14.7 3.4 2.4 2.3 4.1 24.3 16.6 6.8 6.6 3.3 2.2 19.1 7.9 4.4 12.2 14.3 26.8 10.8 19.0 9.0 3.2 9.7 17.4 20.6 8.2 13.5 15.2 11.9 41.1 10.9 3.7 3.1 14.7 13.7 2.0 5.2 8.1 7.0 3.1 5.3 19.3 14.7 11.6 3.2 29.0 16.7 6.7 9.9 20.6 17.6 15.6 22.0 14.8 11.4 28.0 13.8 9.9 23.3 17.5 10.4 9.0 22.9 4.0 5.0 7.7 21.5 9.0 10.6 10.5 25.6 26.3 4.3 7.3 8.8 8.6 0.4 0.9 0.9 0.1 2.2 0.8 1.1 1.0 0.6 0.6 1.3 1.7 0.5 1.7 0.1 1.0 1.6 0.5 2.9 2.9 6.1 5.5 2.7 2.5 1.2 2.4 1.1 1.2 2.4 4.1 1.9 41.7 19.2 16.6 5.1 3.7 2.7 2.1 8.6 15.5 3.9 2.2 14.7 2.8 20.4 12.9 56.3 6.4 6.1 4.8 15.6 3.8 35.1 5.2 2.8 4.6 7.8 7.4 60.5 4.2 6.6 5.3 7.7 5.6 18.9 6.0 2.9 14.2 2.1 11.8 61.4 4.3 0.0 2.7 0.6 8.8 2.5 3.3 1.8 13.1 2.4 6.1 7.2 20.6 18.9 2.5 3.6 4.5 3.3 2.7 6.0 21.7 18.4 40.3 0.0 5.8 3.9 14.3 12.6 10.5 6.3 4.9 5.0 4.6 7.6 2.1 LONP1 "hLON, LonHS, PIM1, PRSS15" ENSG00000196365 "Lon peptidase 1, mitochondrial" P36776 19 5691834-5720572 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA-binding, Hydrolase, Protease, Serine protease" "Cataract, Deafness, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 196.2" "Cell type enhanced" "Detected in all" "Theca cells: 85.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002034, HPA002192" Supported Enhanced Nucleoplasm,Mitochondria No No 7900 "Cluster 6: Non-specific - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoplasm "HPA002034: AB_2756304, HPA002192: AB_1079695" "unprognostic (6.52e-2)" "unprognostic (1.12e-1)" "unprognostic (2.43e-1)" "unprognostic (2.43e-2)" "unprognostic (2.84e-1)" "unprognostic (2.38e-1)" "unprognostic (1.66e-3)" "unprognostic (5.56e-2)" "unprognostic (2.71e-1)" "unprognostic (7.57e-2)" "unprognostic (4.04e-2)" "unprognostic (1.26e-1)" "unprognostic (1.76e-2)" "unprognostic (1.09e-2)" "unprognostic (1.24e-1)" "unprognostic (1.11e-1)" "unprognostic (2.11e-1)" 30.4 196.2 31.5 22.2 32.7 23.7 27.2 34.6 42.8 24.4 39.9 27.9 22.6 25.2 14.1 27.7 22.6 15.4 76.0 30.8 35.7 43.2 79.1 25.6 24.1 37.6 35.8 26.6 38.2 35.2 41.5 18.5 37.9 26.4 13.2 13.0 30.8 16.6 69.3 28.9 25.5 14.7 30.8 29.5 33.7 24.2 37.2 17.5 34.6 40.7 14.5 28.2 22.4 33.0 108.4 111.0 35.6 114.0 41.4 29.2 110.4 67.2 52.7 71.0 86.0 96.3 37.7 134.3 91.4 70.6 68.0 45.0 92.1 81.1 34.2 80.0 78.0 74.5 97.5 127.6 190.4 169.7 74.9 55.0 114.6 67.5 132.6 34.1 57.5 183.9 200.9 259.4 33.0 71.8 85.5 101.6 127.6 43.6 143.1 89.4 50.9 146.6 39.3 63.9 94.2 94.1 59.4 85.2 242.2 24.9 50.3 211.9 41.2 36.0 39.2 100.7 99.2 272.3 182.6 121.4 161.7 185.0 66.2 4.5 2.4 0.5 3.4 3.7 2.3 4.0 3.1 3.4 2.6 3.7 3.8 2.6 0.3 2.7 1.5 3.9 2.7 1.7 31.5 32.7 34.6 42.8 30.8 35.7 37.6 35.8 37.9 30.8 37.2 33.0 12.6 6.4 13.1 18.3 14.1 8.3 11.1 14.9 11.4 26.9 14.2 12.7 19.8 15.7 14.3 27.6 6.2 28.8 8.4 40.1 46.9 33.9 6.5 24.0 16.3 15.3 11.4 17.1 13.5 28.0 31.9 13.3 29.6 25.6 5.7 51.1 11.4 47.0 30.8 21.9 17.4 26.4 22.4 14.6 8.6 6.3 12.8 16.4 14.2 9.4 17.8 24.9 8.2 10.6 15.7 26.0 16.8 17.3 17.6 16.8 27.5 50.2 17.0 26.5 19.7 17.9 24.7 12.0 14.4 11.0 10.7 35.0 10.7 85.0 35.1 11.4 LRPPRC "GP130, LRP130, LSFC" ENSG00000138095 "Leucine rich pentatricopeptide repeat containing" P42704 2 43886224-43995989 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA transport, Transcription, Transcription regulation, Transport" "DNA-binding, RNA-binding" "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033786, HPA036408, HPA036409" Enhanced Enhanced Mitochondria No No 210000 "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB033786: AB_2137450, HPA036408: AB_10670438, HPA036409: AB_2675108" "unprognostic (1.49e-1)" "unprognostic (1.30e-1)" "unprognostic (1.61e-3)" "prognostic unfavorable (1.72e-5)" "unprognostic (1.68e-1)" "unprognostic (8.34e-3)" "prognostic unfavorable (2.31e-7)" "unprognostic (1.02e-1)" "unprognostic (1.25e-1)" "unprognostic (1.11e-1)" "unprognostic (2.44e-3)" "unprognostic (7.68e-2)" "prognostic favorable (6.65e-6)" "unprognostic (9.07e-2)" "unprognostic (1.92e-1)" "unprognostic (1.12e-1)" "unprognostic (5.00e-2)" 32.2 33.2 30.1 23.8 31.3 49.6 41.6 39.3 35.4 23.9 49.2 50.6 33.4 32.5 28.4 28.4 27.6 18.2 47.0 30.8 31.8 63.5 48.3 19.6 31.2 33.0 30.4 34.1 30.4 48.7 19.2 27.2 35.2 27.7 48.9 40.4 27.8 25.3 100.9 30.2 30.3 27.6 30.2 24.3 27.1 33.2 32.1 29.3 31.2 93.5 31.7 27.0 22.5 36.3 127.8 101.9 62.3 80.0 58.1 79.9 108.0 82.7 59.4 88.0 67.3 164.4 65.7 181.7 78.4 50.8 58.8 105.2 118.8 86.3 116.8 110.2 75.2 164.2 76.5 217.9 85.5 239.9 71.4 77.3 73.8 81.6 130.4 49.2 71.2 53.6 246.5 71.5 75.8 68.5 126.8 273.7 104.0 123.8 71.8 139.7 140.7 147.6 95.3 115.3 111.0 107.3 93.6 120.6 154.5 79.2 90.1 140.6 62.6 63.2 86.4 66.9 89.2 72.5 87.4 156.2 60.0 144.1 55.6 10.5 16.5 2.9 13.3 16.2 25.5 22.5 18.0 17.9 23.5 24.5 24.8 21.9 1.2 20.3 18.9 9.6 16.3 20.2 30.1 31.3 39.3 35.4 30.8 31.8 33.0 30.4 35.2 30.2 32.1 36.3 29.2 22.4 34.1 56.8 46.2 46.3 27.2 34.6 46.1 66.4 37.6 30.4 97.2 32.9 35.4 46.0 31.3 37.1 22.5 33.1 21.5 25.6 5.3 31.2 48.2 30.4 27.5 58.4 91.6 17.7 23.6 32.4 40.2 40.1 29.2 51.0 22.1 55.1 25.2 65.6 96.5 49.2 20.3 38.8 25.9 6.3 25.1 28.9 21.4 38.4 36.8 24.5 23.7 55.3 94.9 20.0 33.0 23.7 34.4 31.9 36.6 62.3 25.8 57.0 13.1 45.8 32.6 27.2 33.3 53.9 44.3 33.2 32.2 63.7 76.0 31.9 MALSU1 "C7orf30, mtRsfA" ENSG00000156928 "Mitochondrial assembly of ribosomal large subunit 1" Q96EH3 7 23298739-23311729 "Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "AN3-CA: 47.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020487, HPA052210" Approved Enhanced Mitochondria "Intracellular and membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA020487: AB_1845757, HPA052210: AB_2681762" "unprognostic (3.62e-1)" "unprognostic (3.68e-1)" "unprognostic (1.43e-1)" "unprognostic (4.66e-3)" "unprognostic (5.24e-3)" "prognostic unfavorable (9.71e-4)" "unprognostic (1.08e-1)" "unprognostic (1.51e-2)" "unprognostic (9.79e-2)" "unprognostic (1.83e-3)" "unprognostic (3.15e-2)" "unprognostic (7.15e-2)" "unprognostic (2.37e-2)" "unprognostic (1.25e-1)" "unprognostic (1.43e-2)" "unprognostic (4.51e-2)" "unprognostic (1.68e-1)" 2.6 3.2 2.8 1.6 2.9 2.0 2.2 3.3 3.7 1.9 3.7 2.7 1.0 1.8 2.3 3.9 2.3 1.4 5.1 2.7 2.7 3.1 5.6 2.0 2.9 2.5 2.5 2.6 2.9 2.3 2.0 3.4 2.5 1.6 1.7 1.8 1.9 2.3 6.3 1.8 1.8 1.8 2.4 1.8 2.2 4.9 2.9 1.5 3.3 6.4 1.9 2.1 1.9 3.0 9.2 11.4 8.8 47.8 7.8 5.4 7.6 6.1 5.0 6.2 5.7 19.7 8.1 8.8 7.0 4.4 27.5 8.7 7.9 4.3 7.6 4.2 12.9 5.2 15.0 30.4 5.0 12.2 3.2 4.6 6.5 5.3 5.8 41.5 5.8 8.5 16.5 2.3 7.9 6.4 8.4 37.2 15.1 18.0 29.0 6.5 6.7 12.4 6.1 8.1 7.0 8.5 5.0 8.9 16.1 17.2 4.5 7.3 9.8 5.2 4.0 10.0 12.5 2.6 8.6 14.7 20.6 15.0 17.3 0.7 1.0 0.7 0.8 0.8 1.0 1.0 1.2 1.0 1.0 1.0 1.4 0.9 0.7 0.9 0.7 0.9 1.2 1.0 2.8 2.9 3.3 3.7 2.7 2.7 2.5 2.5 2.5 2.4 2.9 3.0 40.5 38.5 41.7 12.7 32.1 43.7 54.8 58.3 30.1 29.1 38.6 60.8 97.1 37.1 40.0 44.1 16.7 77.6 25.7 22.3 115.4 90.6 168.5 50.2 31.9 38.9 19.2 35.3 14.7 96.3 68.7 44.9 16.3 31.7 14.5 41.5 44.3 106.8 54.0 18.5 16.6 32.5 50.8 26.3 15.1 33.6 49.4 22.3 35.6 8.4 44.5 46.8 30.9 18.6 20.2 73.2 28.2 49.2 34.9 61.2 38.1 117.6 44.6 35.8 32.9 35.6 65.6 82.2 75.2 42.4 44.2 49.8 25.2 61.7 44.4 49.2 MAVS "Cardif, IPS-1, KIAA1271, VISA" ENSG00000088888 "Mitochondrial antiviral signaling protein" Q7Z434 20 3846799-3876123 "Predicted membrane proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 100.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009187, HPA049850, HPA053524" Enhanced Enhanced Mitochondria NA NA 600000 "Cluster 14: Monocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "CAB009187: , HPA049850: AB_2680912, HPA053524: AB_2682177" "unprognostic (1.30e-2)" "unprognostic (4.51e-2)" "unprognostic (2.17e-1)" "unprognostic (6.67e-2)" "unprognostic (1.42e-1)" "unprognostic (1.75e-1)" "unprognostic (1.18e-3)" "unprognostic (2.23e-2)" "unprognostic (2.30e-2)" "unprognostic (5.95e-2)" "prognostic favorable (3.81e-4)" "unprognostic (1.92e-1)" "prognostic favorable (4.13e-5)" "unprognostic (4.97e-2)" "unprognostic (3.03e-1)" "unprognostic (3.12e-2)" "unprognostic (7.39e-2)" 14.2 12.5 13.0 11.5 16.0 10.3 13.0 13.9 13.6 11.6 14.1 19.4 14.8 12.0 8.4 14.9 13.2 6.7 21.3 12.1 11.5 15.8 15.5 13.3 9.9 18.6 15.7 16.8 17.6 15.4 12.1 9.4 15.9 14.2 15.4 8.1 13.0 10.3 37.5 18.9 16.9 9.6 14.0 14.3 15.4 4.9 16.1 10.4 14.0 29.2 10.8 14.3 11.0 16.6 31.6 36.0 14.3 17.9 38.8 26.2 11.2 18.7 23.8 19.5 14.2 28.4 19.9 13.6 11.1 26.4 55.6 38.7 17.3 28.0 19.9 8.4 8.4 26.3 14.6 45.5 21.4 16.6 10.6 26.7 23.4 33.2 19.6 19.4 20.1 17.6 30.2 10.1 19.3 28.5 25.3 14.1 9.2 15.7 19.6 18.8 19.9 13.7 20.8 31.2 10.7 11.2 21.3 41.0 18.1 20.3 21.9 15.3 30.5 26.5 9.7 31.7 22.1 20.7 26.6 9.4 10.5 20.1 13.7 1.7 2.1 2.0 1.4 1.6 1.0 1.1 1.1 1.1 1.4 1.3 1.2 1.2 1.9 1.8 1.9 1.7 0.9 1.6 13.0 16.0 13.9 13.6 12.1 11.5 18.6 15.7 15.9 14.0 16.1 16.6 16.6 57.7 48.5 24.8 17.3 2.2 13.9 3.7 19.4 34.0 19.9 13.2 61.0 58.6 21.7 29.5 16.7 33.6 22.5 100.0 13.7 25.9 1.1 16.1 27.5 26.8 34.7 17.1 13.6 30.5 27.5 22.8 25.0 16.6 8.8 36.5 44.3 45.7 25.5 45.4 15.9 32.6 2.0 37.7 2.9 3.2 30.7 20.7 1.8 15.9 32.4 20.7 20.6 12.5 19.9 32.7 29.5 28.2 14.2 18.1 42.8 19.6 16.2 33.7 32.9 26.2 17.5 6.2 4.1 15.6 2.0 18.1 16.7 27.5 57.9 16.6 MCCC2 MCCB ENSG00000131844 "Methylcrotonoyl-CoA carboxylase 2" Q9HCC0 5 71587288-71658706 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 120.5" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 107.0" "Cancer enhanced" "Detected in all" "prostate cancer: 81.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038300, HPA038301, HPA061546" Enhanced Enhanced Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 44: Endometrium - Transcription" Mitochondria "HPA038300: AB_2675941, HPA038301: AB_10670661, HPA061546: AB_2684557" "unprognostic (2.39e-1)" "unprognostic (6.89e-3)" "prognostic favorable (3.62e-4)" "unprognostic (1.79e-2)" "unprognostic (1.89e-2)" "unprognostic (8.07e-2)" "prognostic favorable (1.70e-4)" "unprognostic (1.01e-1)" "unprognostic (3.37e-1)" "unprognostic (5.39e-2)" "unprognostic (2.90e-1)" "unprognostic (2.38e-1)" "prognostic favorable (6.43e-8)" "unprognostic (1.27e-1)" "unprognostic (1.29e-1)" "unprognostic (5.15e-2)" "unprognostic (3.47e-2)" 21.3 47.6 13.4 13.5 13.7 6.0 60.0 12.4 15.5 21.3 24.9 30.5 27.2 14.4 38.9 25.4 17.2 15.2 54.9 12.0 13.1 73.3 120.5 13.4 17.8 14.8 13.4 14.2 24.6 32.8 14.1 14.2 14.8 48.2 35.9 12.2 28.2 20.6 34.4 19.8 20.7 11.7 16.3 15.6 25.8 8.6 16.0 14.2 44.6 35.4 21.5 27.0 15.0 18.4 38.5 52.4 21.4 82.5 22.4 23.0 36.9 16.4 29.4 35.7 25.7 91.1 46.9 90.4 62.8 25.9 28.0 30.8 37.8 58.8 44.3 47.6 45.6 48.2 24.7 100.5 39.2 24.4 42.8 29.5 30.1 32.6 25.8 15.8 31.7 24.9 63.2 31.6 24.9 103.0 0.3 42.9 29.0 33.2 27.2 46.3 64.5 130.9 92.5 66.9 32.9 36.7 80.1 111.8 38.8 10.1 92.7 59.6 22.7 14.4 22.1 26.1 49.9 22.4 46.2 54.6 23.7 66.3 36.6 2.0 8.4 1.9 6.5 13.5 8.5 9.7 8.4 7.4 19.4 9.9 8.3 9.1 1.3 14.7 8.1 8.1 12.1 8.3 13.4 13.7 12.4 15.5 12.0 13.1 14.8 13.4 14.8 16.3 16.0 18.4 9.1 16.0 23.6 27.4 26.8 13.3 17.5 20.2 22.2 12.6 54.9 28.3 61.5 20.0 22.3 16.5 6.2 48.5 17.6 26.3 21.5 20.6 4.3 94.0 24.0 15.1 29.5 13.9 22.2 18.2 23.0 13.1 30.1 107.0 12.7 22.7 9.7 93.1 18.0 3.3 21.6 22.8 8.2 12.1 11.2 9.8 13.7 14.0 12.4 11.2 17.9 15.4 20.6 30.2 28.0 15.3 17.0 20.3 27.2 29.6 23.6 59.1 17.7 10.8 6.6 15.2 9.0 4.2 12.0 35.9 13.8 63.6 17.9 30.9 33.9 20.9 MCL1 "BCL2L3, Mcl-1" ENSG00000143384 "MCL1 apoptosis regulator, BCL2 family member" Q07820 1 150560895-150579738 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Differentiation" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 685.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 106.3" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 12 "U-698: 4726.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002781, HPA008455, HPA031125, CAB068195" Enhanced Enhanced Mitochondria Yes No "Cluster 52: Eosinophils - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Mitochondria "CAB002781: , CAB068195: AB_2665695, HPA008455: AB_1079334, HPA031125: AB_10602026" "unprognostic (3.82e-2)" "unprognostic (8.79e-2)" "unprognostic (9.15e-2)" "unprognostic (2.05e-2)" "unprognostic (1.34e-1)" "unprognostic (3.91e-2)" "unprognostic (3.16e-2)" "unprognostic (2.43e-2)" "unprognostic (1.29e-1)" "unprognostic (8.60e-2)" "unprognostic (1.57e-2)" "unprognostic (1.65e-2)" "prognostic unfavorable (7.16e-4)" "unprognostic (3.22e-2)" "unprognostic (1.94e-1)" "unprognostic (4.87e-2)" "unprognostic (4.46e-2)" 297.8 149.2 72.9 264.9 75.0 685.1 175.0 77.0 84.2 143.4 85.0 137.1 99.4 98.5 41.8 199.3 190.7 278.8 139.1 65.3 81.5 125.2 404.6 237.1 161.2 86.4 77.8 105.3 161.7 89.2 82.8 146.9 79.4 96.3 120.1 90.1 124.7 56.4 153.8 189.2 133.6 171.4 80.6 171.5 167.0 41.3 91.4 128.9 133.3 160.1 157.1 302.6 124.6 75.8 140.2 74.8 131.9 73.3 262.9 262.2 175.8 164.8 174.5 173.0 139.4 91.9 112.3 184.9 102.2 120.2 80.3 187.7 101.7 203.3 166.7 154.8 68.3 76.4 109.9 106.2 204.7 130.6 151.3 147.3 221.3 170.6 330.0 159.5 192.7 49.4 168.1 225.3 234.2 160.3 64.6 80.7 242.0 122.9 131.9 94.7 111.1 85.9 195.2 103.7 95.9 134.2 125.6 135.9 232.4 191.2 100.4 195.2 251.6 109.2 119.4 55.5 212.8 310.2 409.5 4726.7 189.5 95.1 141.9 23.3 19.8 51.8 15.0 17.4 17.4 12.6 19.0 16.6 16.6 14.0 22.8 17.6 106.3 10.6 16.2 9.4 30.1 11.2 72.9 75.0 77.0 84.2 65.3 81.5 86.4 77.8 79.4 80.6 91.4 75.8 366.0 198.7 295.5 12.4 339.2 489.2 394.7 142.6 434.2 38.7 339.3 229.9 84.8 228.8 148.8 33.1 60.5 108.6 398.5 491.8 41.1 196.4 209.2 187.5 310.8 241.9 259.6 61.8 6.5 174.7 203.4 278.4 228.3 365.7 343.8 209.0 229.2 218.8 262.7 11.8 5.5 309.0 107.8 453.6 930.9 347.0 72.7 614.2 273.9 30.0 250.6 101.2 94.7 10.1 6.8 183.4 345.1 60.9 831.8 293.4 233.1 68.9 110.3 78.0 78.9 350.3 217.4 47.4 35.4 372.2 572.0 270.4 499.8 126.0 205.7 401.1 MDH2 ENSG00000146701 "Malate dehydrogenase 2" P40926 7 76048051-76067508 "Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" Oxidoreductase "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 697.1;tongue: 601.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019714, HPA019716, HPA019848, HPA026720" Enhanced Enhanced Mitochondria No No 14000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA019714: AB_1853678, HPA019716: AB_1853680, HPA019848: AB_1853683, HPA026720: AB_1853685" "unprognostic (3.20e-2)" "unprognostic (2.85e-1)" "unprognostic (1.11e-1)" "unprognostic (1.43e-2)" "unprognostic (5.55e-3)" "unprognostic (8.94e-2)" "unprognostic (6.45e-2)" "unprognostic (3.77e-2)" "unprognostic (3.60e-1)" "unprognostic (2.02e-2)" "unprognostic (1.40e-1)" "unprognostic (9.70e-2)" "prognostic favorable (1.49e-5)" "unprognostic (8.57e-2)" "unprognostic (9.64e-2)" "unprognostic (5.68e-2)" "unprognostic (2.66e-1)" 76.9 163.4 68.0 51.4 73.6 71.9 73.9 62.1 83.9 67.4 81.3 118.7 112.7 69.2 34.7 144.9 66.8 38.0 367.5 73.5 69.9 121.7 215.5 60.7 62.4 66.7 61.4 64.1 118.3 90.5 70.7 45.2 67.0 67.3 80.3 40.2 98.8 56.8 697.1 119.5 94.4 60.0 56.3 75.6 103.2 60.2 64.1 60.4 62.3 601.9 66.2 85.6 82.4 66.6 176.5 278.4 99.2 250.7 110.3 121.2 172.0 113.9 145.8 159.4 143.2 246.2 204.7 261.3 51.1 151.1 172.6 174.4 256.3 170.0 112.7 192.1 368.3 144.6 138.7 229.9 135.2 229.3 144.6 153.7 149.7 155.2 229.3 124.9 150.9 160.5 466.3 149.4 149.7 389.6 206.4 402.1 222.8 306.6 344.3 164.3 121.7 379.9 149.9 225.5 247.4 226.9 114.6 567.5 247.0 124.9 323.4 260.0 117.7 160.0 151.6 175.5 232.7 166.5 148.1 290.8 138.6 289.1 249.1 95.4 129.9 63.3 102.4 148.8 107.1 122.2 113.7 111.2 176.0 110.2 109.0 102.6 34.0 107.4 164.2 157.2 156.6 175.8 68.0 73.6 62.1 83.9 73.5 69.9 66.7 61.4 67.0 56.3 64.1 66.6 98.8 51.3 65.9 7.8 110.2 135.9 190.8 437.9 118.4 68.0 151.8 165.5 486.2 135.8 217.3 115.8 18.8 328.1 104.9 242.3 448.0 269.8 263.7 108.0 97.9 96.8 169.7 97.2 13.0 333.1 334.0 112.6 111.1 104.8 54.5 150.9 88.5 246.6 248.1 72.3 15.0 280.6 288.9 132.6 113.5 161.5 99.4 117.6 181.5 9.4 171.4 85.7 126.7 8.0 12.8 255.0 252.1 99.3 149.8 197.3 433.3 466.3 139.0 67.3 85.5 114.7 150.9 157.8 65.3 256.6 166.1 294.8 105.4 233.4 372.7 234.7 MIPEP MIP ENSG00000027001 "Mitochondrial intermediate peptidase" Q99797 13 23730189-23889400 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 108.0;Oligodendrocytes: 62.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 64.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030676, HPA031669, HPA031670" Approved Enhanced Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA030676: AB_10598907, HPA031669: AB_10600986, HPA031670: AB_10602198" "unprognostic (2.05e-1)" "unprognostic (3.17e-2)" "unprognostic (3.75e-3)" "unprognostic (3.72e-2)" "unprognostic (1.24e-1)" "unprognostic (1.23e-1)" "unprognostic (2.41e-1)" "unprognostic (2.21e-1)" "unprognostic (4.69e-2)" "unprognostic (1.12e-1)" "unprognostic (7.54e-2)" "unprognostic (4.76e-1)" "prognostic favorable (7.66e-12)" "unprognostic (1.62e-2)" "unprognostic (4.95e-2)" "unprognostic (2.79e-1)" "unprognostic (6.90e-3)" 6.3 9.6 3.7 6.2 4.3 5.3 11.1 3.2 5.0 7.5 13.4 12.9 8.8 7.2 12.4 11.5 17.3 7.7 18.4 14.4 4.0 25.4 12.0 7.1 5.1 4.0 5.0 5.4 8.2 14.6 5.4 4.7 4.6 10.9 13.1 6.1 9.7 8.7 13.9 21.4 7.6 7.8 4.0 4.3 8.6 9.8 3.7 6.0 11.1 16.9 7.8 7.7 6.4 4.9 14.6 16.1 7.8 18.4 17.4 23.4 16.6 10.3 16.0 15.1 12.7 21.7 28.1 17.0 10.2 8.4 13.3 35.8 18.1 21.6 18.8 9.9 11.5 7.4 7.0 18.8 14.3 17.5 3.9 11.6 26.4 15.7 13.9 12.7 19.2 12.7 14.5 2.7 24.0 10.8 12.6 9.8 10.8 64.8 16.1 13.8 21.0 14.8 33.7 9.6 18.2 6.1 11.0 17.8 21.8 9.8 18.3 9.7 10.7 9.2 7.6 15.3 11.2 2.6 4.0 9.1 15.9 8.8 11.7 0.0 3.0 1.3 7.4 3.7 9.3 8.7 7.1 6.8 6.5 7.2 6.7 6.7 0.0 10.3 12.0 5.5 5.2 4.0 3.7 4.3 3.2 5.0 14.4 4.0 4.0 5.0 4.6 4.0 3.7 4.9 2.5 16.0 8.6 18.9 5.9 39.9 7.7 13.8 6.2 3.6 6.2 5.8 108.0 11.5 12.6 9.2 6.2 9.8 2.4 8.2 29.4 23.4 8.2 26.0 8.5 5.4 6.0 4.6 43.8 10.6 9.3 8.0 7.1 8.5 2.5 4.2 3.6 5.9 9.7 15.2 47.5 7.1 14.2 3.5 5.0 7.4 6.8 4.3 5.4 12.2 3.4 5.5 5.2 18.1 62.8 8.6 7.0 8.6 4.9 7.5 6.6 25.6 46.3 11.4 0.0 7.3 5.7 9.7 19.0 10.1 42.3 5.1 4.0 8.9 13.6 5.6 MPC1 "BRP44L, CGI-129, dJ68L15.3, SLC54A1" ENSG00000060762 "Mitochondrial pyruvate carrier 1" Q9Y5U8 6 166364919-166383013 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 739.7;tongue: 559.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 950.0;Distal tubular cells: 1721.8;Proximal tubular cells: 573.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045119, HPA055790" Enhanced Enhanced Mitochondria NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA045119: AB_10960421, HPA055790: AB_2682923" "unprognostic (3.30e-2)" "prognostic favorable (1.45e-4)" "unprognostic (5.24e-3)" "unprognostic (1.68e-1)" "unprognostic (3.17e-2)" "unprognostic (2.85e-2)" "unprognostic (7.61e-2)" "prognostic favorable (1.29e-4)" "unprognostic (3.27e-1)" "unprognostic (1.19e-1)" "unprognostic (1.11e-3)" "unprognostic (5.64e-2)" "prognostic favorable (4.79e-11)" "unprognostic (4.13e-2)" "unprognostic (1.03e-1)" "unprognostic (7.48e-2)" "unprognostic (8.45e-2)" 61.7 39.6 105.9 33.4 119.5 57.0 52.8 129.7 153.1 52.4 108.0 97.7 84.8 35.7 44.8 71.5 34.7 41.7 739.7 101.2 127.8 259.9 411.2 44.6 44.3 119.2 123.9 43.4 66.0 141.8 38.1 23.7 119.5 43.5 89.9 57.3 87.7 42.3 319.4 40.9 63.8 38.5 117.1 35.0 96.1 22.2 121.5 48.6 82.9 559.2 44.2 47.4 34.9 132.4 25.6 7.5 31.3 107.7 88.4 49.8 45.2 29.1 47.1 45.1 43.9 38.8 17.9 53.6 50.9 45.4 36.1 24.5 47.0 36.7 31.9 36.1 79.0 27.5 35.4 132.6 36.6 104.9 34.1 40.0 51.0 36.8 26.7 13.7 36.9 80.8 94.2 84.1 28.6 40.5 73.1 193.7 16.1 148.0 35.5 39.1 51.7 134.9 85.4 20.5 96.7 85.7 33.6 145.8 34.0 25.9 34.5 154.3 25.3 25.7 26.8 91.6 30.0 55.8 42.2 46.3 23.5 127.0 42.1 60.7 60.0 90.1 41.7 98.3 39.4 33.1 48.5 45.1 72.2 25.4 44.7 43.3 54.6 40.5 128.5 43.0 69.1 49.8 105.9 119.5 129.7 153.1 101.2 127.8 119.2 123.9 119.5 117.1 121.5 132.4 56.1 118.6 48.0 64.6 51.7 45.6 44.2 83.6 29.0 61.1 74.2 79.1 950.0 187.3 67.6 106.7 10.4 22.0 54.2 219.1 1721.8 89.3 66.8 73.7 50.7 51.7 37.2 72.6 49.0 140.3 78.3 74.1 63.7 93.2 71.0 28.0 47.5 391.0 121.4 48.8 74.7 122.1 166.8 89.6 81.7 10.2 66.5 80.3 129.9 20.6 104.7 199.9 58.7 32.2 108.0 65.2 125.0 89.9 114.5 32.0 162.0 573.6 46.3 66.7 92.1 76.9 80.4 163.2 79.6 67.3 55.8 24.4 58.4 39.9 146.7 53.6 MRPL10 "L10MT, MGC17973, MRP-L10, MRP-L8, MRPL8, RPML8" ENSG00000159111 "Mitochondrial ribosomal protein L10" Q7Z7H8 17 47823272-47831541 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021234, HPA029885" Enhanced Enhanced Mitochondria NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" Mitochondria "HPA021234: AB_1854098, HPA029885: AB_2673233" "unprognostic (6.84e-3)" "unprognostic (1.03e-1)" "unprognostic (8.05e-2)" "unprognostic (9.09e-3)" "unprognostic (1.97e-1)" "unprognostic (4.01e-3)" "prognostic unfavorable (6.67e-4)" "unprognostic (5.21e-2)" "unprognostic (1.03e-1)" "unprognostic (8.91e-2)" "unprognostic (1.38e-1)" "unprognostic (6.16e-2)" "unprognostic (1.29e-1)" "unprognostic (2.82e-1)" "unprognostic (1.87e-2)" "unprognostic (1.60e-1)" "unprognostic (6.87e-2)" 32.1 32.8 35.6 14.4 36.6 24.7 29.7 36.9 39.7 30.1 33.2 40.9 25.6 31.4 22.8 27.1 29.8 21.9 58.1 34.9 36.7 31.2 29.9 20.1 26.2 36.5 36.0 48.8 41.0 28.9 17.3 23.2 36.2 24.8 23.1 21.7 22.1 25.5 64.2 23.8 26.7 26.5 35.7 28.2 36.2 20.1 37.4 25.9 23.1 52.4 26.9 37.9 25.4 36.8 36.8 80.0 33.4 33.0 78.3 71.3 61.6 32.2 54.0 54.2 46.4 155.7 49.2 59.1 71.9 42.0 36.0 33.6 48.3 62.6 48.0 57.6 76.4 47.2 41.7 110.0 67.4 42.8 25.5 80.8 53.2 64.4 90.7 63.7 52.9 58.4 64.8 56.6 42.3 73.3 43.2 55.0 55.1 64.0 76.5 34.7 63.7 66.5 59.9 35.8 39.2 63.2 23.9 26.9 68.7 62.9 81.2 45.5 32.3 47.5 39.0 32.3 45.1 100.1 82.4 48.0 41.4 32.3 32.4 29.8 37.3 18.5 61.6 39.6 59.1 31.8 42.4 55.3 43.0 36.6 35.6 42.2 14.5 26.6 32.9 26.0 52.5 42.0 35.6 36.6 36.9 39.7 34.9 36.7 36.5 36.0 36.2 35.7 37.4 36.8 17.1 6.4 13.6 4.2 19.2 12.5 20.8 42.5 27.9 15.3 25.3 31.5 31.5 20.0 19.5 14.7 6.2 90.5 50.9 17.9 46.9 43.8 22.0 7.9 16.3 21.7 8.5 30.3 5.4 54.7 60.0 23.3 20.4 11.0 8.8 31.8 20.7 15.6 41.7 32.0 6.6 20.7 32.6 31.4 10.8 30.5 24.5 17.3 16.0 2.8 31.8 24.4 44.3 7.1 8.2 40.4 14.7 24.0 22.8 18.4 30.8 47.5 6.1 13.7 6.6 17.5 28.0 23.2 29.2 24.1 12.5 77.3 48.5 49.4 31.9 18.8 MRPL45 MGC11321 ENSG00000278845 "Mitochondrial ribosomal protein L45" 17 38297023-38323217 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebral cortex: 8.4" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "AF22: 35.7;Daudi: 80.9;K-562: 57.0;REH: 43.2;RPMI-8226: 34.4;RT4: 33.9;U-266/84: 52.1;U-698: 56.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023373, HPA023385" Enhanced Enhanced Mitochondria NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 32: Non-specific - Translation" Mitochondria "HPA023373: AB_1854114, HPA023385: AB_1854115" "unprognostic (8.56e-3)" "unprognostic (4.09e-2)" "unprognostic (1.11e-2)" "unprognostic (3.08e-1)" "unprognostic (9.50e-2)" "unprognostic (2.22e-3)" "unprognostic (1.11e-2)" "unprognostic (1.60e-1)" "unprognostic (7.21e-2)" "unprognostic (1.37e-2)" "unprognostic (3.65e-1)" "unprognostic (1.35e-1)" "unprognostic (6.01e-3)" "unprognostic (3.07e-1)" "unprognostic (1.00e-1)" "unprognostic (2.40e-1)" "unprognostic (8.13e-2)" 24.0 26.7 1.5 2.2 1.9 1.9 24.1 1.6 8.4 21.1 2.2 24.6 0.0 21.4 0.0 25.3 19.8 4.0 32.1 1.6 1.6 26.0 30.7 15.2 8.0 1.7 1.6 28.3 36.8 9.0 13.1 1.7 1.7 18.0 5.7 1.3 22.4 0.0 61.8 26.5 19.6 0.7 1.5 16.3 30.0 9.5 1.6 2.6 18.2 0.0 6.9 22.1 20.1 1.6 0.0 0.5 35.7 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 26.8 80.9 0.2 0.0 24.2 0.5 0.2 0.0 0.1 0.0 0.3 31.1 0.0 2.1 12.7 0.0 0.2 0.0 0.3 0.1 0.0 0.1 0.0 0.0 57.0 0.0 0.2 0.0 23.1 0.0 0.3 0.1 0.0 43.2 0.2 34.4 0.0 33.9 0.1 0.2 0.2 0.6 0.2 0.1 0.1 0.2 0.5 15.1 0.1 0.0 0.3 23.2 52.1 56.9 0.1 0.0 0.4 0.6 6.7 2.2 5.3 8.2 6.4 7.6 7.7 4.1 11.3 6.8 9.8 6.6 0.2 9.8 2.3 4.8 6.6 6.3 1.5 1.9 1.6 8.4 1.6 1.6 1.7 1.6 1.7 1.5 1.6 1.6 20.4 12.8 12.1 6.8 23.8 30.2 39.3 54.6 42.7 10.9 41.3 37.7 46.5 32.9 23.9 25.8 8.4 69.3 16.3 11.3 60.7 41.5 18.3 21.6 25.6 26.9 16.3 45.9 10.4 37.5 67.7 25.1 24.5 21.1 23.5 31.4 22.5 30.4 42.6 16.8 12.0 27.4 34.6 39.1 21.1 15.0 20.8 22.2 19.6 1.9 43.8 13.0 22.6 7.5 9.2 29.6 15.5 16.6 23.7 28.8 32.0 64.0 21.6 11.1 6.6 28.4 25.2 30.6 18.0 31.9 32.4 71.1 19.3 42.6 41.8 33.3 MRPS36 "DC47, MRP-S36" ENSG00000134056 "Mitochondrial ribosomal protein S36" P82909 5 69217760-69230158 "Predicted intracellular proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 546.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035802, HPA056795" Supported Enhanced Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA035802: AB_10600933, HPA056795: AB_2683237" "unprognostic (1.19e-1)" "unprognostic (6.78e-3)" "unprognostic (4.08e-2)" "unprognostic (1.02e-1)" "unprognostic (1.92e-1)" "unprognostic (2.96e-3)" "unprognostic (1.99e-1)" "unprognostic (7.49e-2)" "unprognostic (1.49e-1)" "unprognostic (1.99e-2)" "unprognostic (1.38e-1)" "unprognostic (3.90e-1)" "prognostic favorable (5.02e-6)" "unprognostic (2.06e-1)" "unprognostic (2.49e-1)" "unprognostic (1.37e-2)" "unprognostic (4.84e-3)" 20.3 18.4 20.1 12.7 20.3 21.0 16.5 21.3 26.3 12.7 20.2 23.6 24.1 12.8 15.4 20.3 12.7 10.4 67.3 20.1 21.5 49.2 38.0 14.7 15.1 20.3 20.6 12.4 14.7 31.3 9.8 13.0 20.6 14.4 24.3 18.9 13.7 12.1 47.0 12.6 24.0 12.4 20.3 11.6 21.8 8.6 20.8 15.7 17.2 67.7 16.7 16.6 14.0 20.5 29.2 27.6 19.1 26.4 32.8 33.1 50.3 25.6 24.5 32.1 39.4 38.6 31.8 31.2 51.9 21.8 71.8 29.3 32.1 38.8 31.7 36.8 33.6 21.3 31.4 43.4 38.7 22.9 27.9 34.6 27.3 30.7 14.5 33.4 24.0 31.9 25.7 22.9 28.7 31.8 35.3 34.9 14.2 26.8 31.9 20.6 33.2 47.9 56.4 32.5 26.6 25.9 26.2 37.9 46.3 30.9 29.0 32.9 17.6 14.3 24.5 32.0 44.5 23.9 41.9 41.6 25.0 42.1 19.1 36.3 22.1 29.3 22.7 32.0 25.4 31.1 25.7 25.8 27.9 25.0 22.8 24.7 25.1 26.5 30.2 27.4 40.3 17.7 20.1 20.3 21.3 26.3 20.1 21.5 20.3 20.6 20.6 20.3 20.8 20.5 64.5 115.4 83.6 16.3 76.5 81.4 101.1 204.0 83.1 26.3 72.4 109.3 333.1 97.2 104.3 88.3 14.6 126.8 67.5 220.5 401.1 118.4 127.7 123.3 79.5 57.2 92.8 97.2 20.4 139.5 192.4 68.6 67.2 113.0 56.4 41.4 52.1 216.1 127.1 28.6 21.4 162.8 120.1 102.4 67.5 45.2 64.7 72.9 106.7 10.3 142.0 61.8 56.7 10.6 17.1 137.1 190.1 69.2 60.5 100.5 256.6 546.3 86.4 45.9 72.3 78.7 92.3 66.1 37.9 86.9 76.9 123.3 64.2 76.9 168.1 114.6 MTFR1 "CHPPR, FAM54A2, KIAA0009" ENSG00000066855 "Mitochondrial fission regulator 1" Q15390 8 65644734-65771261 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Early spermatids: 365.5;Late spermatids: 792.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "hTERT-HME1: 107.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023152, HPA056120" Uncertain Supported Mitochondria,Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 34: Spermatids - Unknown function" Mitochondria Cytosol "HPA023152: AB_1854176, HPA056120: AB_2683043" "prognostic unfavorable (4.06e-4)" "unprognostic (4.58e-2)" "unprognostic (4.01e-2)" "unprognostic (4.57e-2)" "unprognostic (6.56e-3)" "unprognostic (3.93e-2)" "unprognostic (1.66e-1)" "unprognostic (3.28e-2)" "unprognostic (1.50e-1)" "unprognostic (3.53e-1)" "unprognostic (5.69e-3)" "unprognostic (5.44e-2)" "unprognostic (6.63e-3)" "unprognostic (1.84e-1)" "unprognostic (1.26e-1)" "prognostic unfavorable (5.21e-4)" "unprognostic (8.25e-2)" 9.9 15.2 4.4 6.2 6.1 4.9 10.0 4.7 6.9 9.8 4.6 11.3 12.4 8.4 12.0 10.2 6.3 6.6 7.6 4.3 4.9 31.8 34.9 5.9 4.7 5.2 5.5 6.2 8.8 11.6 3.9 7.6 5.1 7.3 12.0 34.0 8.4 8.5 9.7 8.2 12.5 9.5 4.5 4.0 14.7 19.7 5.3 4.6 11.5 7.3 6.8 8.9 7.6 6.6 34.3 25.1 19.7 22.7 25.7 25.6 15.7 22.3 20.3 26.8 27.9 21.5 34.5 19.0 7.0 21.7 26.6 21.9 44.3 30.0 35.6 6.9 24.0 23.6 16.8 43.1 32.7 6.2 10.9 17.5 31.1 34.7 107.9 15.2 33.1 13.8 32.8 19.0 30.8 30.9 21.1 14.2 20.5 74.9 22.5 10.7 26.9 15.9 32.5 30.2 8.6 12.9 21.9 36.7 29.6 19.6 40.5 13.3 25.8 15.9 22.4 38.8 19.6 18.4 12.9 13.6 19.8 25.0 21.6 1.3 0.8 0.3 0.5 0.6 0.7 0.4 0.7 0.6 0.8 0.3 0.6 0.7 0.2 0.2 0.3 0.5 0.7 0.4 4.4 6.1 4.7 6.9 4.3 4.9 5.2 5.5 5.1 4.5 5.3 6.6 6.8 19.2 9.8 5.9 6.1 16.8 12.3 13.5 10.2 0.0 9.7 4.8 7.4 18.6 12.2 11.0 0.0 25.0 6.9 11.9 56.7 22.6 365.5 7.5 10.0 10.0 4.8 12.6 13.1 24.1 29.0 10.1 14.3 8.2 5.1 9.2 8.9 39.9 9.7 0.0 16.4 12.6 20.3 6.3 7.0 792.9 16.8 6.5 14.2 11.2 3.8 0.0 4.1 18.6 42.4 20.0 9.6 12.0 10.7 20.6 20.0 112.7 16.1 0.0 6.6 7.5 13.1 93.0 35.9 18.4 19.5 39.1 4.5 20.6 15.7 16.6 MTHFD1L "DKFZP586G1517, FLJ21145, FTHFSDC1" ENSG00000120254 "Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like" Q6UB35 6 150865679-151101887 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "One-carbon metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 84.0;Extravillous trophoblasts: 166.5;Granulosa cells: 86.9;Microglial cells: 126.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 4 "dendritic cells: 1.1;T-cells: 1.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015006, HPA029040, HPA029041, HPA050052, HPA074911" Approved Enhanced Mitochondria NA NA 89000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Mitochondria "HPA015006: AB_1854178, HPA029040: AB_2672879, HPA029041: AB_2672880, HPA050052: AB_2680998, HPA074911: AB_2686723" "unprognostic (3.66e-2)" "prognostic unfavorable (1.68e-5)" "unprognostic (1.02e-1)" "prognostic unfavorable (7.28e-4)" "unprognostic (3.25e-1)" "prognostic unfavorable (5.10e-4)" "prognostic unfavorable (8.33e-5)" "unprognostic (6.35e-3)" "unprognostic (2.45e-1)" "unprognostic (1.44e-1)" "unprognostic (1.02e-1)" "unprognostic (1.32e-1)" "unprognostic (1.11e-2)" "unprognostic (2.93e-2)" "unprognostic (3.51e-1)" "unprognostic (2.91e-1)" "prognostic unfavorable (8.69e-5)" 12.5 12.2 7.1 11.4 6.7 13.2 7.9 25.1 7.4 7.1 8.3 7.4 3.2 8.4 6.2 6.7 7.1 5.9 11.5 6.4 9.8 12.7 5.6 19.5 11.1 11.5 10.1 14.6 10.7 6.8 9.2 14.3 11.0 5.5 7.9 7.5 3.2 7.0 1.3 6.0 5.2 10.0 11.6 9.2 6.0 9.9 8.4 8.6 10.9 0.5 10.8 12.8 4.2 15.4 40.6 35.1 44.9 110.0 11.5 40.0 108.4 63.0 68.3 62.1 75.7 71.8 37.4 152.3 41.1 96.9 36.8 42.7 72.4 61.8 76.8 63.4 65.3 62.7 60.4 66.1 72.4 115.7 9.8 47.7 76.9 60.6 109.8 55.5 105.5 81.6 150.9 76.2 65.0 86.1 57.1 23.9 45.5 40.7 32.1 67.2 33.2 67.1 42.1 19.6 44.1 32.5 83.9 36.7 53.0 40.6 11.5 79.5 80.6 41.4 90.6 91.9 90.5 62.3 63.5 154.0 68.8 105.7 54.0 0.0 0.2 0.0 0.2 0.3 0.4 0.2 0.6 0.7 1.1 0.3 0.5 0.6 0.0 0.3 0.3 0.5 1.8 0.2 7.1 6.7 25.1 7.4 6.4 9.8 11.5 10.1 11.0 11.6 8.4 15.4 6.9 0.0 1.7 47.7 6.9 6.5 8.0 15.7 1.8 0.0 3.3 4.1 2.4 1.5 9.8 14.7 0.0 25.8 1.4 2.6 7.9 9.0 44.9 11.3 18.4 10.7 1.2 5.0 84.0 18.1 166.5 14.4 8.2 22.2 0.0 86.9 6.1 1.7 24.9 0.0 73.8 3.0 46.8 3.0 13.3 6.2 0.6 13.8 35.6 126.5 2.4 0.0 2.1 60.8 59.3 19.2 1.4 7.9 14.0 31.3 0.9 15.2 5.3 0.0 0.0 8.7 13.1 0.5 6.8 2.3 3.4 73.6 4.0 42.9 4.0 35.1 MTIF2 IF-2mt ENSG00000085760 "Mitochondrial translational initiation factor 2" P46199 2 55236595-55269347 "Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 80.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006021, HPA061422" Approved Enhanced Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA006021: AB_2147687, HPA061422: AB_2684514" "unprognostic (2.91e-2)" "unprognostic (9.58e-2)" "unprognostic (1.52e-2)" "unprognostic (1.87e-3)" "unprognostic (8.86e-2)" "unprognostic (5.57e-2)" "unprognostic (9.76e-3)" "unprognostic (1.88e-1)" "unprognostic (6.85e-3)" "unprognostic (3.01e-2)" "unprognostic (6.58e-3)" "unprognostic (1.76e-1)" "unprognostic (3.98e-2)" "unprognostic (2.54e-2)" "unprognostic (1.66e-1)" "unprognostic (9.45e-3)" "unprognostic (1.33e-1)" 17.5 18.2 14.8 16.7 16.6 14.2 19.6 17.0 18.0 14.4 19.1 27.7 27.2 10.8 17.8 18.7 13.0 11.6 31.9 15.0 17.4 24.8 33.0 12.3 20.6 16.8 16.1 11.4 26.7 24.2 10.9 13.4 17.0 14.4 31.5 15.5 18.5 14.0 44.2 16.1 22.0 12.4 16.4 17.4 20.7 12.2 16.8 16.8 20.5 48.8 20.3 15.0 13.2 18.1 42.4 39.8 23.2 40.2 27.8 37.7 53.1 37.8 29.9 35.5 30.9 48.0 39.8 69.1 69.6 34.5 39.7 36.7 55.2 54.5 58.3 77.1 42.6 63.3 30.9 89.4 53.4 101.6 36.4 41.7 54.9 49.1 101.9 31.4 29.1 37.8 114.4 38.4 37.0 35.2 31.5 68.2 49.3 52.2 48.5 32.7 74.3 67.1 34.4 36.8 41.3 26.2 33.7 54.8 71.0 27.8 28.9 33.6 28.5 37.0 42.5 44.6 62.8 71.3 68.3 18.8 39.3 74.3 29.7 5.6 10.3 9.7 9.0 12.7 11.7 7.5 9.2 8.6 13.5 9.5 11.2 11.5 4.0 16.7 10.8 6.6 12.2 6.8 14.8 16.6 17.0 18.0 15.0 17.4 16.8 16.1 17.0 16.4 16.8 18.1 10.9 22.4 23.6 9.8 16.6 7.6 19.1 18.8 13.6 0.0 15.5 14.2 80.7 22.8 16.9 7.3 0.0 32.1 22.2 18.7 29.4 33.6 16.9 24.0 17.6 13.5 19.2 22.1 8.9 33.5 31.1 14.0 17.3 15.6 21.5 26.7 10.4 29.9 23.8 0.0 9.7 19.3 18.3 25.1 7.0 18.2 9.0 19.0 8.8 12.2 35.5 0.0 21.6 8.5 13.6 29.8 15.3 10.5 21.5 11.8 26.3 25.7 22.5 0.0 6.6 14.0 20.6 30.1 17.8 20.3 7.4 16.3 13.3 29.0 33.3 15.1 MYO19 "FLJ22865, MYOHD1" ENSG00000278259 "Myosin XIX" Q96H55 17 36495636-36543435 "Predicted intracellular proteins" "Actin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 81.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021415, HPA059715" Approved Enhanced Mitochondria,Cytosol NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Mitochondria Cytosol "HPA021415: AB_2266815, HPA059715: AB_2684111" "unprognostic (3.12e-1)" "unprognostic (2.38e-1)" "unprognostic (8.44e-3)" "unprognostic (1.46e-1)" "unprognostic (2.02e-1)" "unprognostic (4.89e-3)" "prognostic unfavorable (8.33e-6)" "unprognostic (1.07e-3)" "unprognostic (1.39e-2)" "unprognostic (2.41e-1)" "unprognostic (1.67e-1)" "unprognostic (3.70e-3)" "unprognostic (1.47e-2)" "unprognostic (1.50e-2)" "unprognostic (1.57e-1)" "unprognostic (1.89e-1)" "unprognostic (4.17e-2)" 7.8 5.5 2.3 7.1 2.6 13.1 8.0 2.3 3.0 11.3 3.5 11.7 13.0 7.3 5.2 22.1 7.5 4.9 5.6 2.3 2.4 13.5 11.1 7.8 5.7 3.0 2.4 6.8 13.2 17.0 9.5 6.4 3.2 7.9 14.6 2.1 15.4 3.9 8.5 24.2 13.0 7.2 2.2 8.4 14.4 9.6 2.9 6.4 9.4 4.5 10.0 7.3 14.5 3.1 41.6 47.3 21.7 25.1 10.1 12.5 32.5 34.0 27.0 53.2 57.9 42.6 46.4 21.9 15.6 23.3 20.0 66.5 48.0 38.3 36.8 18.9 24.0 30.6 58.8 29.4 8.4 36.5 40.0 6.9 20.2 41.6 40.8 13.5 22.2 29.7 46.5 24.2 28.2 28.9 25.3 29.4 23.9 44.1 20.4 32.8 30.7 28.4 27.7 32.3 37.9 18.5 44.9 31.7 15.4 30.3 55.2 17.6 15.9 32.8 41.1 47.5 65.3 19.8 41.4 21.3 22.8 24.7 44.5 0.5 0.6 0.4 1.1 0.4 0.9 0.6 0.7 1.1 1.2 0.5 0.6 1.2 0.0 1.4 0.2 0.6 0.6 0.4 2.3 2.6 2.3 3.0 2.3 2.4 3.0 2.4 3.2 2.2 2.9 3.1 13.1 9.6 12.0 23.8 12.3 29.6 12.3 14.4 23.9 18.4 11.0 12.3 4.4 17.2 8.6 5.5 35.5 12.0 9.6 24.4 1.9 10.7 81.4 10.6 12.7 10.6 10.8 24.6 25.8 13.3 21.6 9.6 23.9 16.7 2.5 20.4 6.8 9.5 10.9 3.3 36.4 23.5 14.2 7.9 10.1 20.8 12.5 7.8 3.6 10.3 11.0 3.9 15.5 22.6 24.4 16.4 13.9 9.8 19.4 26.4 23.0 4.4 6.4 24.8 0.0 13.3 9.0 19.7 19.4 29.1 23.4 7.3 13.0 9.9 32.5 16.3 NDUFAF2 "B17.2L, mimitin, MMTN, NDUFA12L" ENSG00000164182 "NADH:ubiquinone oxidoreductase complex assembly factor 2" Q8N183 5 60945177-61154531 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA048082, HPA054776" Supported Enhanced Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 47: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA048082: AB_2680254, HPA054776: AB_2682598" "unprognostic (7.28e-2)" "unprognostic (6.83e-2)" "unprognostic (1.37e-1)" "unprognostic (2.46e-3)" "unprognostic (2.41e-2)" "unprognostic (2.74e-2)" "prognostic unfavorable (2.56e-4)" "unprognostic (1.06e-1)" "unprognostic (4.76e-2)" "unprognostic (8.40e-3)" "unprognostic (1.28e-1)" "unprognostic (2.71e-1)" "prognostic unfavorable (2.49e-4)" "unprognostic (1.79e-2)" "unprognostic (6.10e-2)" "unprognostic (2.37e-1)" "unprognostic (4.66e-2)" 42.7 39.2 34.8 23.3 35.7 18.0 38.5 34.6 56.0 34.7 33.0 48.3 21.0 31.6 17.5 36.4 31.3 17.0 57.7 34.8 37.5 37.4 32.2 24.9 19.7 36.2 37.9 37.7 35.7 31.2 45.1 14.5 37.3 31.9 26.2 22.0 25.8 23.0 80.2 22.6 24.9 25.9 34.4 18.3 35.9 31.2 35.4 13.0 23.0 46.5 18.8 43.4 33.4 35.0 109.0 51.9 41.6 129.1 80.7 113.8 70.3 129.8 71.1 85.2 103.7 99.4 84.0 150.8 127.5 91.2 141.2 44.2 72.6 113.8 103.6 66.0 104.3 52.1 95.7 99.4 115.6 72.5 26.2 59.7 119.2 74.9 226.0 53.9 74.7 64.0 79.5 76.3 90.9 89.6 64.2 108.0 35.3 41.2 135.0 77.3 115.1 192.7 83.1 46.1 84.8 33.0 74.7 72.7 136.0 35.8 86.1 40.4 68.6 55.5 82.8 125.3 134.2 46.0 73.2 170.8 75.9 123.2 66.3 0.4 18.3 2.4 17.3 19.1 21.1 23.0 22.3 21.1 32.1 15.2 18.6 20.1 0.8 27.1 15.8 11.0 31.7 12.2 34.8 35.7 34.6 56.0 34.8 37.5 36.2 37.9 37.3 34.4 35.4 35.0 40.8 12.8 28.0 23.8 32.8 60.5 64.6 62.2 34.1 27.9 47.9 59.8 87.6 45.8 39.6 38.6 12.5 20.8 18.7 29.8 93.9 55.1 175.7 41.8 95.1 35.8 24.7 28.8 62.2 56.6 49.2 60.4 28.5 40.3 20.3 27.2 31.8 94.6 51.4 42.1 68.8 59.3 40.7 29.5 59.1 22.2 76.7 29.0 44.4 40.3 24.7 34.0 22.6 61.9 71.3 69.8 52.2 62.1 29.0 144.1 32.2 151.4 25.9 29.1 26.3 55.2 60.1 108.4 73.9 63.0 63.6 14.2 34.0 48.5 65.7 71.1 NDUFB6 "B17, CI" ENSG00000165264 "NADH:ubiquinone oxidoreductase subunit B6" O95139 9 32553001-32573184 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 583.9;Distal tubular cells: 534.1;Early spermatids: 889.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044001, HPA053334" Supported Enhanced Mitochondria No No "Cluster 50: Neutrophils - Cellular senescence" "Cluster 39: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Mitochondria "HPA044001: AB_10959448, HPA053334: AB_2682116" "unprognostic (4.09e-1)" "prognostic favorable (3.18e-4)" "unprognostic (1.81e-2)" "unprognostic (1.53e-2)" "unprognostic (1.50e-1)" "unprognostic (1.49e-1)" "unprognostic (1.14e-1)" "unprognostic (6.10e-2)" "unprognostic (1.18e-1)" "unprognostic (1.35e-3)" "unprognostic (1.22e-1)" "unprognostic (1.49e-1)" "prognostic favorable (7.47e-10)" "unprognostic (2.70e-1)" "unprognostic (1.82e-1)" "unprognostic (1.26e-1)" "unprognostic (1.83e-1)" 38.6 50.8 42.7 30.7 45.3 31.0 35.9 47.1 48.1 34.1 42.8 41.8 44.6 38.1 26.8 43.8 36.0 17.6 144.9 44.5 46.5 73.6 66.7 30.5 26.9 44.5 42.9 29.7 31.0 41.8 40.3 22.5 44.6 28.5 29.1 30.7 37.0 22.0 168.0 28.2 43.6 26.7 45.9 28.8 43.5 53.5 44.3 28.7 33.2 101.8 24.5 34.1 33.4 47.1 106.4 63.7 69.6 80.1 46.7 43.0 44.5 69.5 56.5 62.8 68.8 62.8 46.5 78.4 70.5 48.2 65.1 58.8 66.5 76.8 47.0 108.6 106.0 187.2 88.8 65.9 45.2 94.4 46.3 44.8 36.7 56.8 42.9 47.5 57.6 118.4 61.0 86.1 71.9 61.2 128.1 221.2 73.6 90.7 140.1 86.7 58.4 73.1 72.0 39.3 69.7 78.4 80.2 91.1 50.7 52.0 86.3 72.0 51.4 67.9 103.8 75.7 103.8 38.0 77.0 131.5 113.7 65.6 32.7 126.3 97.6 136.1 76.9 94.3 74.5 106.0 81.4 80.0 108.8 89.0 82.3 87.4 302.1 91.9 116.3 152.7 112.4 110.2 42.7 45.3 47.1 48.1 44.5 46.5 44.5 42.9 44.6 45.9 44.3 47.1 69.5 125.0 111.6 15.3 76.2 94.2 106.2 222.9 90.0 44.1 64.6 72.6 583.9 101.5 141.4 108.5 6.2 191.8 69.4 115.8 534.1 172.5 889.5 106.9 86.1 101.0 64.6 196.7 21.8 166.7 143.0 109.5 83.6 86.4 90.5 64.3 74.3 182.2 160.8 18.5 23.8 152.5 209.5 55.0 96.4 146.9 91.6 78.4 160.1 3.7 108.6 115.3 90.6 18.1 21.3 144.4 124.9 89.9 165.7 80.0 201.0 520.3 152.3 56.5 105.2 94.8 151.3 182.0 125.9 139.7 96.7 104.1 81.0 95.6 167.3 103.8 NDUFB8 "ASHI, CI-ASHI" ENSG00000166136 "NADH:ubiquinone oxidoreductase subunit B8" O95169 10 100523740-100530000 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 876.5;Proximal tubular cells: 881.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA003886, HPA065549" Supported Enhanced Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA003886: AB_1079463, HPA065549: " "unprognostic (4.07e-2)" "unprognostic (1.95e-3)" "unprognostic (2.28e-1)" "unprognostic (7.33e-2)" "unprognostic (4.88e-2)" "unprognostic (5.78e-2)" "unprognostic (3.02e-1)" "unprognostic (6.46e-2)" "unprognostic (8.33e-2)" "unprognostic (9.09e-2)" "unprognostic (1.25e-2)" "unprognostic (8.23e-2)" "unprognostic (4.62e-2)" "unprognostic (1.10e-1)" "unprognostic (1.21e-1)" "unprognostic (1.15e-1)" "unprognostic (5.10e-2)" 152.6 199.3 431.2 103.4 439.3 171.5 135.8 427.1 606.3 127.3 416.7 237.8 161.0 145.8 163.0 170.2 132.4 88.0 482.4 444.8 441.9 249.9 262.0 108.6 132.0 438.5 439.4 130.4 115.5 331.0 186.7 83.0 441.9 132.2 145.0 127.1 163.6 135.8 408.9 128.2 147.8 125.5 411.8 133.3 201.0 66.2 442.5 140.6 130.1 512.8 119.9 162.9 132.9 448.3 250.2 419.6 222.3 383.1 159.6 158.8 238.5 168.1 370.9 259.3 278.8 575.4 278.1 260.7 146.4 185.6 189.1 289.5 162.9 269.7 194.5 172.9 417.8 183.9 350.3 465.7 217.6 379.3 302.6 191.6 240.7 249.2 329.3 180.4 283.7 361.1 194.5 159.3 218.4 304.1 369.7 472.9 144.7 324.3 377.9 252.4 237.6 346.1 298.8 281.3 147.9 209.7 122.0 227.4 250.9 147.3 338.2 332.8 185.5 139.5 158.7 151.5 296.8 288.4 286.4 334.8 277.6 398.2 159.3 299.4 530.8 478.1 406.0 558.8 483.1 616.1 498.0 468.1 589.7 546.7 538.1 514.0 122.7 478.0 489.6 655.0 817.6 1113.4 431.2 439.3 427.1 606.3 444.8 441.9 438.5 439.4 441.9 411.8 442.5 448.3 184.8 76.9 132.7 41.8 107.6 0.0 187.1 0.0 12.5 186.4 162.2 210.2 392.9 204.5 48.3 198.6 58.4 333.1 175.8 109.0 876.5 268.1 24.9 105.8 86.3 142.7 105.6 114.3 72.6 264.7 305.1 128.8 35.2 87.1 109.7 112.0 153.8 346.5 399.1 153.1 82.6 171.6 0.0 184.4 0.0 56.0 218.1 142.2 0.0 33.7 231.0 219.5 158.6 40.2 62.3 250.6 191.7 217.4 59.3 203.2 560.2 881.6 85.2 183.5 170.9 117.2 176.0 85.5 83.1 31.5 0.0 307.7 112.9 225.5 237.6 221.5 NDUFV3 CI-10k ENSG00000160194 "NADH:ubiquinone oxidoreductase subunit V3" P56181 21 42879644-42913304 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 88.0" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 770.8;Early spermatids: 502.9;Late spermatids: 1712.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019791, HPA020463, HPA030427, CAB034142" Enhanced Enhanced Mitochondria NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 36: HEL - Hemostasis" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "CAB034142: AB_2298212, HPA019791: AB_1854357, HPA020463: AB_1854358, HPA030427: AB_10603024" "unprognostic (1.62e-1)" "unprognostic (2.17e-3)" "unprognostic (1.31e-1)" "unprognostic (1.04e-1)" "unprognostic (1.10e-1)" "unprognostic (1.11e-2)" "unprognostic (4.69e-1)" "unprognostic (2.97e-2)" "unprognostic (1.05e-1)" "unprognostic (3.13e-1)" "unprognostic (3.85e-3)" "unprognostic (1.54e-1)" "unprognostic (1.45e-1)" "unprognostic (6.56e-2)" "unprognostic (9.30e-3)" "unprognostic (2.14e-1)" "unprognostic (1.94e-1)" 20.5 18.1 9.2 3.2 9.3 6.8 17.5 9.5 8.9 16.6 7.5 24.2 5.1 19.1 7.9 18.9 17.3 2.4 47.2 7.6 8.0 18.0 26.9 13.7 3.1 9.5 9.7 19.1 24.0 7.5 16.6 3.0 9.2 16.3 4.1 7.7 17.3 4.0 88.0 19.0 16.1 3.6 8.4 17.0 19.7 20.9 9.2 2.5 14.9 21.1 3.2 18.4 15.9 10.1 3.3 4.9 9.1 8.1 7.9 5.0 10.4 6.6 4.2 5.2 3.4 10.6 6.2 4.9 4.2 4.1 11.7 5.4 8.8 8.1 3.5 2.8 7.4 20.1 8.7 9.0 9.4 6.0 7.8 8.0 8.2 6.9 12.0 4.2 6.1 5.6 13.5 7.3 5.6 10.5 3.7 6.2 10.2 15.7 6.9 4.6 5.3 12.3 9.5 7.5 5.8 4.7 9.0 10.3 4.8 4.4 10.2 4.6 8.9 3.2 3.0 4.4 4.8 12.1 7.1 3.5 5.7 7.7 4.6 3.1 5.7 3.8 2.8 7.1 2.4 2.9 2.4 2.2 5.0 3.5 2.9 2.8 3.3 4.4 6.6 4.4 2.7 2.8 9.2 9.3 9.5 8.9 7.6 8.0 9.5 9.7 9.2 8.4 9.2 10.1 42.8 54.5 46.7 14.4 36.5 19.9 53.7 97.7 24.5 81.2 64.9 65.7 770.8 92.9 58.6 90.1 68.8 57.5 32.5 89.3 230.9 86.5 502.9 84.5 64.9 48.1 78.3 112.4 19.4 101.5 59.5 57.2 55.5 56.9 31.6 45.5 68.2 334.5 114.4 57.2 22.1 114.8 87.5 88.3 38.1 1712.0 66.5 62.3 37.4 17.8 86.4 88.7 49.4 15.6 19.5 98.6 80.9 62.4 39.0 109.3 176.4 372.6 85.9 104.7 72.3 54.0 66.1 243.5 77.1 50.0 23.4 89.9 29.9 83.8 95.4 65.3 NGRN DSC92 ENSG00000182768 "Neugrin, neurite outgrowth associated" Q9NPE2 15 90265659-90275778 "Predicted intracellular proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 385.3;skeletal muscle: 376.8" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 75.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041367, HPA076267" Approved Supported "Nucleoplasm,Cytokinetic bridge,Mitochondria" "Intracellular and membrane" Yes No "Cluster 35: T-regs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 59: Non-specific - Transcription" Mitochondria "Nucleoplasm, Cytokinetic bridge" "HPA041367: AB_10796668, HPA076267: " "unprognostic (2.82e-1)" "unprognostic (1.04e-2)" "unprognostic (1.66e-3)" "unprognostic (2.34e-1)" "unprognostic (2.21e-1)" "unprognostic (3.19e-2)" "unprognostic (2.94e-2)" "unprognostic (5.00e-2)" "unprognostic (7.78e-2)" "unprognostic (1.93e-2)" "unprognostic (5.22e-2)" "unprognostic (7.22e-2)" "unprognostic (3.31e-2)" "unprognostic (2.10e-1)" "unprognostic (2.05e-1)" "unprognostic (1.68e-3)" "unprognostic (3.21e-1)" 61.0 91.8 322.8 32.9 334.0 31.7 61.4 312.4 385.3 68.8 312.1 47.0 39.7 63.4 98.3 51.7 65.3 47.1 133.0 332.8 329.8 71.7 59.1 50.3 31.8 316.3 322.1 67.8 46.4 87.6 3.0 46.4 318.1 80.1 51.1 157.0 46.3 88.9 376.8 32.6 35.6 74.6 324.8 37.0 41.5 54.2 334.5 39.6 74.0 291.8 37.4 69.2 2.7 320.9 62.1 127.8 151.7 99.7 138.4 63.9 70.4 100.7 88.4 110.5 94.0 133.2 90.5 38.4 113.8 108.9 110.2 118.2 120.3 64.7 121.5 42.6 104.6 61.0 88.4 110.6 117.7 44.5 36.1 83.4 183.3 60.8 132.9 83.7 79.5 45.7 105.0 64.7 112.8 106.5 35.9 53.5 152.7 198.8 55.0 65.6 72.8 63.1 109.8 168.3 145.8 117.0 107.1 90.1 239.1 149.1 141.9 82.6 64.6 138.3 92.3 85.7 161.7 96.9 268.2 66.4 76.8 90.1 106.4 66.4 62.1 99.0 87.2 65.2 109.9 107.7 106.1 101.9 59.2 105.7 122.6 106.8 23.4 86.7 76.0 62.8 133.5 108.0 322.8 334.0 312.4 385.3 332.8 329.8 316.3 322.1 318.1 324.8 334.5 320.9 10.8 19.2 27.4 21.5 26.2 7.1 10.6 3.7 75.1 10.4 9.1 5.8 10.1 1.5 21.6 5.5 10.4 5.9 5.0 12.1 5.9 33.6 1.9 16.2 14.6 15.8 26.5 12.0 58.3 23.4 4.5 23.0 30.1 9.4 20.3 5.5 7.5 3.8 4.2 16.8 54.0 14.4 4.1 3.8 3.6 4.0 9.0 8.4 8.8 16.9 11.6 15.1 0.0 12.5 22.2 29.9 20.0 8.6 25.0 9.2 12.6 7.8 59.8 11.2 13.1 10.5 19.6 5.2 4.3 55.2 5.1 6.7 19.9 5.7 15.4 8.7 OCIAD2 MGC45416 ENSG00000145247 "OCIA domain containing 2" Q56VL3 4 48885019-48906937 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 155.4" "Cell type enhanced" "Detected in many" "Pancreatic endocrine cells: 1277.4;Proximal enterocytes: 702.0;Proximal tubular cells: 1384.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HBEC3-KT: 325.2;U-251 MG: 399.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040979, HPA041090" Enhanced Enhanced Mitochondria No No "Cluster 20: T-cells - T-cell receptor" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Mitochondria "HPA040979: AB_10795497, HPA041090: AB_10796236" "unprognostic (4.29e-1)" "unprognostic (2.69e-1)" "unprognostic (3.76e-2)" "prognostic favorable (7.37e-4)" "unprognostic (3.49e-2)" "unprognostic (1.66e-2)" "unprognostic (9.05e-2)" "unprognostic (1.23e-1)" "unprognostic (2.00e-1)" "prognostic favorable (6.56e-4)" "prognostic unfavorable (6.89e-4)" "unprognostic (1.38e-1)" "prognostic favorable (2.67e-5)" "unprognostic (1.10e-1)" "unprognostic (8.54e-2)" "unprognostic (8.24e-3)" "prognostic favorable (2.34e-4)" 9.2 20.4 14.1 22.1 13.1 16.3 23.4 10.3 15.3 19.8 14.1 54.7 122.3 20.7 46.9 25.8 22.4 32.4 14.3 17.8 15.6 155.4 129.5 19.0 34.6 13.1 13.2 8.7 26.9 44.4 33.6 8.6 11.7 23.8 49.9 26.9 40.2 29.2 4.4 20.0 88.4 15.0 11.6 12.6 85.0 6.3 13.7 53.6 37.4 3.9 40.3 28.1 12.0 12.7 208.9 108.5 1.6 0.0 0.0 0.0 2.7 53.3 23.9 28.4 26.9 0.0 249.4 35.7 230.1 30.5 248.0 65.5 29.7 325.2 29.1 83.8 22.6 0.1 78.6 0.1 25.6 101.7 0.3 14.7 150.8 0.1 61.1 81.4 115.5 140.2 0.1 17.6 30.3 78.3 172.2 70.2 102.5 234.2 145.2 38.5 0.1 59.4 288.7 135.0 230.3 69.5 75.4 25.5 5.4 0.8 26.2 25.2 195.6 0.2 215.1 1.2 399.5 49.5 59.6 113.3 163.0 0.3 0.4 208.4 3.5 69.1 101.6 1.5 136.9 168.0 191.0 147.3 18.1 156.7 247.2 165.0 11.2 156.0 1.3 122.4 338.7 137.7 14.1 13.1 10.3 15.3 17.8 15.6 13.1 13.2 11.7 11.6 13.7 12.7 135.9 28.9 70.6 2.0 102.5 109.0 146.6 401.4 81.4 17.6 152.7 190.6 39.2 194.5 224.2 176.6 29.2 46.2 66.3 359.7 217.2 510.5 1.4 197.5 22.9 103.3 306.4 38.9 10.1 570.2 11.4 14.9 157.5 190.8 36.8 75.3 31.1 193.9 44.3 1.7 11.6 301.3 341.8 6.4 27.0 2.5 5.0 21.7 65.8 5.6 15.9 49.9 82.4 2.5 1.8 1277.4 311.6 21.4 53.5 180.1 702.0 1384.9 171.4 77.6 0.0 3.7 41.8 2.6 3.2 105.2 131.4 15.3 129.8 52.1 188.6 239.2 OGDH "E1k, KGD1, OGDC-E1, OGDH2" ENSG00000105953 "Oxoglutarate dehydrogenase" Q02218 7 44606572-44709066 "Citric acid cycle related proteins, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 324.0;skeletal muscle: 363.6;tongue: 374.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 114.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019514, HPA020347" Supported Enhanced Mitochondria No No 130000 "Cluster 39: Non-specific - mRNA processing" "Cluster 8: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA019514: AB_1854772, HPA020347: AB_1854773" "unprognostic (1.96e-2)" "unprognostic (1.40e-1)" "unprognostic (4.39e-1)" "unprognostic (5.64e-3)" "unprognostic (3.02e-3)" "unprognostic (1.20e-1)" "unprognostic (3.45e-1)" "unprognostic (7.58e-2)" "unprognostic (1.74e-1)" "unprognostic (1.52e-2)" "unprognostic (3.38e-1)" "unprognostic (3.30e-2)" "prognostic favorable (2.22e-14)" "unprognostic (1.53e-1)" "unprognostic (1.62e-1)" "unprognostic (2.23e-2)" "unprognostic (5.88e-3)" 64.9 67.4 35.0 39.2 39.4 32.1 32.0 42.8 45.4 33.8 119.6 56.3 95.6 40.9 16.6 61.6 34.0 26.9 324.0 34.4 50.6 89.7 39.8 43.4 40.0 44.6 44.4 24.8 27.5 99.9 34.9 33.1 44.2 37.9 41.5 25.9 43.0 46.9 363.6 56.4 87.5 51.0 35.7 39.0 52.5 36.2 43.6 32.1 54.9 374.7 41.5 42.5 37.7 35.6 35.8 73.5 42.2 66.0 63.4 69.8 41.9 54.2 51.3 59.5 50.9 67.2 71.7 156.0 63.0 79.2 119.2 108.2 85.7 81.4 58.4 92.0 22.8 47.4 140.6 33.5 32.8 59.4 51.2 66.0 60.5 85.4 60.9 43.0 82.4 50.7 55.8 45.4 63.7 50.1 59.2 34.1 39.8 97.7 81.8 55.9 30.1 175.9 68.5 104.4 73.2 35.0 78.8 107.6 34.4 75.8 64.2 58.7 66.4 43.4 38.5 76.3 64.0 40.9 84.0 85.9 78.4 65.7 80.4 9.9 21.8 12.6 17.9 28.5 19.5 11.1 20.7 18.1 22.0 9.3 8.5 10.8 12.2 19.3 35.4 10.8 42.1 23.2 35.0 39.4 42.8 45.4 34.4 50.6 44.6 44.4 44.2 35.7 43.6 35.6 19.6 6.4 22.5 49.3 23.1 19.5 12.3 15.9 22.8 21.4 14.4 18.2 114.3 12.8 14.2 47.8 18.8 24.0 20.0 64.5 31.3 14.9 51.0 26.1 15.6 16.0 23.4 32.0 43.3 16.9 16.4 20.6 35.2 38.9 21.5 15.5 17.9 22.6 33.8 62.2 53.1 32.6 12.2 24.5 43.4 24.5 11.8 33.8 21.4 29.0 22.7 14.3 16.5 22.1 36.6 20.9 38.0 17.3 27.8 16.4 82.0 51.8 17.0 24.0 19.7 24.7 20.2 10.6 19.9 28.1 26.3 36.7 27.7 30.3 33.5 18.1 OXCT1 "OXCT, SCOT" ENSG00000083720 "3-oxoacid CoA-transferase 1" P55809 5 41730065-41870425 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 245.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 243.7;Distal tubular cells: 187.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HeLa: 238.7;SiHa: 319.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012047, HPA061425" Enhanced Enhanced Mitochondria "Intracellular and membrane" NA NA 440000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA012047: AB_1854857, HPA061425: AB_2684515" "unprognostic (4.26e-2)" "unprognostic (2.10e-2)" "unprognostic (2.89e-2)" "unprognostic (1.51e-1)" "unprognostic (5.51e-2)" "unprognostic (1.82e-2)" "prognostic unfavorable (1.03e-4)" "unprognostic (7.42e-3)" "unprognostic (1.74e-3)" "unprognostic (1.67e-1)" "unprognostic (2.80e-2)" "unprognostic (3.62e-1)" "prognostic favorable (1.86e-8)" "unprognostic (2.66e-2)" "unprognostic (9.99e-2)" "unprognostic (5.86e-3)" "unprognostic (2.28e-3)" 52.7 15.8 30.4 16.6 34.9 13.3 18.5 23.9 32.7 13.5 15.9 19.2 8.3 14.9 17.6 26.8 12.4 15.2 245.9 36.2 27.1 53.1 1.3 8.0 21.7 19.5 21.4 13.8 5.3 48.6 14.7 5.0 20.0 25.5 21.1 23.6 18.9 29.8 28.5 23.1 12.8 36.6 19.3 11.0 34.2 13.2 25.7 76.8 27.3 42.6 25.9 15.1 13.8 24.5 35.3 1.6 27.9 33.6 84.7 45.0 0.1 62.1 38.9 50.3 30.4 5.7 23.5 91.2 15.0 47.5 25.8 20.5 77.5 55.9 58.5 78.5 9.1 63.9 238.7 11.9 36.8 125.8 20.9 42.7 15.3 49.3 82.2 24.6 46.4 81.6 13.3 114.0 58.1 4.5 105.5 6.1 6.4 0.0 24.5 82.8 78.9 68.7 41.7 2.9 27.9 28.8 319.5 0.3 38.3 2.5 0.4 27.4 28.3 39.7 51.9 68.6 50.6 18.6 16.5 3.6 59.9 90.9 30.9 1.4 1.4 4.7 11.6 1.5 13.8 10.0 11.5 12.7 6.3 7.5 13.6 10.9 0.4 11.3 2.5 2.4 21.5 6.6 30.4 34.9 23.9 32.7 36.2 27.1 19.5 21.4 20.0 19.3 25.7 24.5 8.4 6.4 9.2 37.5 19.2 14.8 11.7 12.4 17.6 14.1 18.8 14.2 243.7 7.2 14.3 11.0 2.1 7.0 18.3 5.0 187.9 5.4 19.1 11.7 18.8 9.8 13.2 23.1 71.5 0.7 11.9 21.3 20.4 31.2 9.5 8.7 6.8 0.3 38.2 13.5 84.2 18.6 12.2 1.3 7.0 8.6 6.2 5.2 16.0 26.2 4.4 11.8 10.3 66.4 46.8 4.8 5.3 7.5 31.3 12.1 2.9 27.4 5.6 21.6 13.1 9.7 24.6 35.6 19.7 27.6 21.6 6.8 26.6 8.6 18.1 9.0 PC PCB ENSG00000173599 "Pyruvate carboxylase" P11498 11 66848417-66958386 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Gluconeogenesis, Lipid biosynthesis, Lipid metabolism" "Ligase, Multifunctional enzyme" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 148.0" "Cell type enhanced" "Detected in many" "Hepatocytes: 201.9;Late spermatids: 53.2" "Cancer enhanced" "Detected in all" "liver cancer: 37.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HeLa: 57.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033742, HPA043922, HPA058765" Enhanced Enhanced Mitochondria Yes No 200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 15: Hepatocytes - Hemostasis" Mitochondria "CAB033742: AB_2283532, HPA043922: AB_2678732, HPA058765: AB_2683812" "unprognostic (2.10e-1)" "unprognostic (1.51e-1)" "unprognostic (1.36e-2)" "unprognostic (8.24e-3)" "unprognostic (3.67e-1)" "unprognostic (3.18e-2)" "unprognostic (2.97e-1)" "unprognostic (3.00e-1)" "unprognostic (3.63e-1)" "prognostic unfavorable (7.86e-5)" "unprognostic (1.54e-1)" "unprognostic (1.17e-1)" "prognostic favorable (8.22e-5)" "unprognostic (8.58e-3)" "unprognostic (5.67e-2)" "unprognostic (9.15e-3)" "unprognostic (1.05e-1)" 60.9 23.7 35.7 2.9 35.5 3.5 28.4 36.6 35.8 3.7 17.5 4.7 6.5 3.8 1.8 9.3 3.2 2.8 4.3 32.4 41.0 23.3 148.0 2.6 1.3 43.4 40.1 5.1 4.9 18.2 8.6 4.4 37.6 7.2 2.8 2.4 35.3 9.3 12.1 4.7 7.7 1.4 37.8 1.5 9.1 10.7 49.0 2.0 4.6 6.6 2.0 2.9 4.4 37.0 6.1 19.3 6.5 17.2 25.4 8.9 6.6 3.4 15.5 6.9 7.5 8.8 6.0 0.0 7.4 6.0 9.6 6.8 7.7 39.5 1.5 2.8 11.0 10.3 57.4 41.2 21.0 0.1 10.8 40.2 10.1 5.8 12.4 4.4 5.7 14.3 17.4 0.0 2.1 44.6 9.2 4.6 12.0 15.1 16.2 8.3 13.0 3.2 5.7 1.9 15.2 21.0 33.6 18.0 15.5 4.8 14.6 2.7 6.3 7.8 6.6 8.8 4.7 3.5 4.8 0.1 7.7 5.7 6.7 0.0 1.3 0.0 0.5 0.3 0.5 0.0 0.1 0.5 0.9 0.2 0.9 0.5 0.1 0.1 0.1 0.3 0.5 0.7 35.7 35.5 36.6 35.8 32.4 41.0 43.4 40.1 37.6 37.8 49.0 37.0 0.9 0.0 3.0 26.4 1.4 1.3 1.6 9.1 2.8 5.6 4.8 5.8 4.4 11.5 3.0 3.7 2.1 17.4 0.6 27.6 1.9 3.1 18.4 2.3 7.1 1.5 9.0 28.0 18.5 1.8 4.2 3.2 5.6 3.0 8.9 16.0 4.6 201.9 12.3 0.0 18.6 5.0 0.0 7.0 1.8 53.2 0.6 1.8 5.4 7.5 18.9 9.4 2.1 10.1 16.7 2.3 8.5 4.1 0.1 3.1 23.6 39.0 1.5 4.8 0.0 2.2 2.2 11.2 4.7 4.1 0.6 25.4 1.2 6.0 6.4 1.3 PCK2 "PEPCK, PEPCK2" ENSG00000100889 "Phosphoenolpyruvate carboxykinase 2, mitochondrial" Q16822 14 24094053-24110598 "Citric acid cycle related proteins, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Gluconeogenesis "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "intestine: 196.1;kidney: 99.1;liver: 374.1" "Group enriched" "Detected in many" 4 "Hepatocytes: 309.3;Proximal enterocytes: 752.6;Proximal tubular cells: 237.1" "Cancer enhanced" "Detected in all" "liver cancer: 91.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 104.7;hTCEpi: 104.7;SK-MEL-30: 103.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB018734, HPA051162, HPA053502" Enhanced Enhanced Mitochondria NA NA 3500000 "Cluster 51: Monocytes - Innate immune response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "CAB018734: AB_2160168, HPA051162: AB_2681368, HPA053502: AB_2682171" "unprognostic (3.38e-2)" "unprognostic (1.13e-1)" "unprognostic (1.50e-2)" "unprognostic (4.07e-1)" "unprognostic (3.11e-1)" "unprognostic (2.10e-1)" "prognostic favorable (2.81e-4)" "unprognostic (3.91e-2)" "unprognostic (1.04e-1)" "unprognostic (2.18e-2)" "unprognostic (1.26e-1)" "unprognostic (3.67e-2)" "unprognostic (1.33e-2)" "unprognostic (2.81e-1)" "unprognostic (3.71e-1)" "unprognostic (2.82e-2)" "unprognostic (1.17e-1)" 25.5 10.7 3.2 8.0 3.9 4.5 21.1 3.8 3.3 6.8 3.4 44.8 196.1 5.8 3.1 20.0 5.9 4.5 5.8 3.1 3.9 99.1 374.1 16.5 8.7 4.6 4.2 3.0 34.8 17.4 8.0 2.8 4.1 9.1 19.2 2.7 18.6 7.1 2.6 12.6 136.3 3.8 4.0 21.7 16.0 19.7 3.9 3.7 18.9 1.2 7.5 10.8 10.0 4.3 17.6 9.8 2.7 18.1 11.0 10.5 46.0 21.5 25.6 17.4 28.4 16.1 19.9 44.6 2.6 33.4 5.6 25.4 18.0 28.1 13.8 22.8 0.8 8.0 5.0 84.2 104.7 15.8 33.4 12.9 104.7 10.6 26.5 5.0 14.0 50.6 23.4 79.3 6.4 74.6 4.0 7.6 3.1 39.4 13.0 8.7 10.5 26.0 5.3 26.7 11.3 18.2 16.5 21.2 103.9 2.6 28.5 24.1 2.7 3.8 19.7 5.6 6.0 53.2 18.6 11.0 10.6 24.5 9.6 0.3 11.6 3.5 4.0 21.6 4.1 11.4 4.5 4.5 15.3 7.3 2.7 2.5 1.3 2.2 22.0 2.5 9.1 6.1 3.2 3.9 3.8 3.3 3.1 3.9 4.6 4.2 4.1 4.0 3.9 4.3 4.8 12.8 28.5 1.3 17.9 3.3 10.2 12.3 5.7 4.7 8.6 5.2 1.8 18.6 8.0 18.4 0.0 4.7 4.3 91.2 35.2 18.9 60.1 1.6 5.2 5.6 9.1 24.4 0.5 76.3 14.3 7.4 16.8 4.5 1.3 1.6 13.2 309.3 63.8 0.0 0.9 60.8 18.3 25.8 5.7 30.8 3.4 16.4 7.2 1.0 22.9 5.8 7.2 0.0 0.1 29.0 87.8 3.0 13.3 7.6 752.6 237.1 4.8 5.5 0.0 3.4 18.7 19.8 1.0 9.1 4.8 3.0 7.6 6.8 72.0 15.0 PHB2 "Bap37, BCAP37, p22, REA" ENSG00000215021 "Prohibitin 2" Q99623 12 6965327-6970780 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB014889, CAB026335, HPA039874" Supported Enhanced Mitochondria NA NA 77000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 5: NTERA-2 - Transcription" "Cluster 32: Non-specific - Translation" Mitochondria "CAB014889: , CAB026335: AB_2283865, HPA039874: AB_2616448" "unprognostic (4.64e-3)" "unprognostic (4.32e-2)" "unprognostic (9.65e-2)" "prognostic unfavorable (3.80e-4)" "unprognostic (3.07e-3)" "unprognostic (1.67e-1)" "unprognostic (2.53e-1)" "unprognostic (1.62e-1)" "unprognostic (1.98e-1)" "unprognostic (7.18e-2)" "unprognostic (1.46e-1)" "unprognostic (2.85e-1)" "unprognostic (1.04e-1)" "unprognostic (5.65e-2)" "unprognostic (1.07e-1)" "unprognostic (8.17e-2)" "unprognostic (5.61e-2)" 134.3 166.6 75.6 95.2 75.6 149.4 138.7 76.7 81.3 152.2 78.8 162.3 149.8 134.0 122.6 168.7 137.0 80.3 157.0 72.9 75.1 112.7 233.4 88.0 141.9 74.8 75.2 244.3 199.5 130.9 76.3 84.9 75.8 114.0 145.4 48.2 138.1 97.8 303.5 150.6 127.4 102.3 75.5 113.6 141.8 36.1 77.5 144.5 103.4 231.1 162.8 135.8 125.4 75.9 270.5 261.1 214.1 295.8 170.6 295.0 469.2 183.6 245.6 329.7 259.8 420.5 283.0 567.8 78.8 187.4 200.6 225.0 395.9 337.5 267.2 306.9 316.1 296.4 146.3 409.2 284.1 488.8 212.4 307.2 229.2 208.0 452.5 331.8 331.4 157.0 270.1 127.1 238.5 277.2 449.0 452.9 813.3 236.8 224.7 307.4 338.3 356.7 270.0 312.8 111.7 372.9 152.2 434.9 503.8 440.1 67.6 379.3 191.8 141.5 227.4 115.2 402.2 128.1 166.3 586.7 186.7 251.0 207.6 78.5 88.3 43.8 84.2 107.2 103.8 102.8 96.2 98.1 138.5 98.1 85.0 85.1 35.4 117.8 94.8 129.0 123.6 114.2 75.6 75.6 76.7 81.3 72.9 75.1 74.8 75.2 75.8 75.5 77.5 75.9 114.1 48.1 54.8 14.7 155.0 74.4 106.8 110.1 191.8 42.9 155.1 230.8 45.1 91.5 62.1 35.0 39.6 212.9 99.8 104.6 115.4 134.1 2.8 68.2 124.8 86.0 100.6 143.7 10.0 162.3 282.2 97.7 100.4 88.0 63.5 177.2 92.1 172.5 163.0 18.5 11.4 142.7 77.3 125.0 70.4 7.2 97.3 105.0 72.9 8.4 131.0 87.3 102.0 12.5 12.9 119.8 90.3 68.8 145.9 99.4 197.3 142.4 40.1 46.8 72.3 109.1 128.7 33.3 57.0 245.3 76.3 170.1 102.9 218.5 268.5 113.4 PMPCA "Alpha-MPP, CLA1, INPP5E, KIAA0123, SCAR2" ENSG00000165688 "Peptidase, mitochondrial processing subunit alpha" Q10713 9 136410641-136423761 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Disease variant, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021648, HPA063735" Supported Enhanced Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA021648: AB_1855491, HPA063735: AB_2685108" "unprognostic (9.80e-2)" "unprognostic (1.96e-2)" "unprognostic (4.03e-1)" "unprognostic (1.69e-2)" "unprognostic (4.01e-2)" "unprognostic (8.19e-2)" "unprognostic (6.09e-2)" "unprognostic (1.19e-2)" "unprognostic (1.97e-1)" "unprognostic (3.32e-2)" "prognostic favorable (8.00e-5)" "unprognostic (9.47e-3)" "prognostic favorable (2.14e-6)" "unprognostic (4.27e-3)" "unprognostic (1.57e-2)" "unprognostic (2.40e-1)" "unprognostic (3.54e-2)" 29.2 58.1 27.0 20.6 27.6 31.4 27.1 27.0 34.6 29.2 36.8 32.2 24.8 26.8 10.4 34.5 27.5 17.9 73.2 28.0 27.3 37.3 110.8 25.4 27.1 27.1 27.6 29.3 28.8 26.9 38.8 20.8 27.9 31.8 15.3 8.8 28.4 16.1 69.2 37.6 30.6 15.3 25.6 38.2 35.3 37.8 27.9 21.4 29.4 50.0 17.0 28.0 27.8 26.7 48.7 87.7 41.8 84.5 30.8 45.0 63.2 49.3 39.6 67.2 48.9 101.1 56.5 67.4 50.5 50.3 36.2 110.2 77.9 72.0 30.0 97.2 92.8 54.6 113.2 123.6 53.9 71.7 44.9 66.3 48.9 52.6 27.0 38.2 58.0 61.2 140.2 43.4 42.6 132.1 68.1 90.1 85.4 86.2 82.2 83.0 59.1 149.9 46.3 33.9 85.4 56.1 66.6 92.9 58.6 28.6 127.6 95.5 48.2 47.8 50.7 39.8 63.8 26.2 37.4 73.5 62.9 61.3 43.9 37.4 50.5 36.5 53.2 51.9 51.4 52.5 49.0 57.2 61.7 48.8 57.9 50.2 11.9 67.2 51.5 31.4 52.7 62.2 27.0 27.6 27.0 34.6 28.0 27.3 27.1 27.6 27.9 25.6 27.9 26.7 17.3 16.0 26.7 14.7 24.2 27.5 40.2 65.0 27.9 24.7 19.3 15.2 35.9 15.7 32.8 22.0 22.9 103.1 22.5 28.0 49.0 32.9 24.6 25.6 23.5 21.7 20.8 23.5 13.8 30.7 50.4 23.7 21.9 26.2 24.7 44.2 19.6 57.2 37.8 18.5 11.4 24.2 44.7 19.2 14.6 15.8 19.0 17.4 16.0 6.5 21.0 22.9 14.4 8.5 8.0 31.6 20.9 22.6 26.6 22.6 25.6 46.9 22.6 27.4 39.5 22.4 27.9 37.7 42.4 23.2 26.9 103.8 21.7 77.0 38.6 28.5 PMPCB "MPPB, MPPP52" ENSG00000105819 "Peptidase, mitochondrial processing subunit beta" O75439 7 103297435-103329511 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040674, HPA074168" Approved Enhanced Mitochondria No No 19000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA040674: AB_10961998, HPA074168: AB_2686671" "prognostic favorable (2.79e-4)" "unprognostic (3.11e-1)" "unprognostic (7.18e-3)" "unprognostic (3.03e-1)" "unprognostic (3.65e-2)" "unprognostic (1.72e-1)" "unprognostic (1.06e-1)" "unprognostic (7.67e-2)" "unprognostic (7.74e-2)" "unprognostic (1.21e-1)" "unprognostic (1.38e-1)" "unprognostic (1.42e-3)" "prognostic favorable (2.95e-8)" "unprognostic (2.59e-2)" "unprognostic (9.79e-2)" "unprognostic (2.40e-1)" "unprognostic (4.39e-2)" 30.8 42.0 16.9 22.3 18.2 53.5 32.5 18.9 22.1 33.3 24.7 33.4 38.0 29.9 26.2 27.7 29.3 25.1 44.9 18.8 18.1 47.4 46.1 22.6 36.4 16.5 16.6 35.4 41.1 39.7 22.4 25.8 17.6 31.5 33.2 25.4 30.6 28.1 34.8 33.2 32.4 26.3 17.2 28.2 35.8 26.7 17.4 30.2 33.4 38.2 33.9 29.3 28.4 19.9 30.2 42.8 49.9 69.4 28.5 57.1 38.0 26.7 45.6 54.3 62.8 47.7 33.7 76.9 41.7 47.9 58.0 37.5 59.7 43.2 49.2 26.4 69.4 26.4 74.0 61.6 35.0 35.0 30.6 53.4 40.5 41.8 39.6 51.3 28.8 55.9 52.5 77.9 48.5 71.1 59.2 82.0 59.2 60.4 52.4 42.7 34.3 79.4 50.3 54.2 62.2 76.5 37.3 108.6 55.8 49.5 45.3 49.1 24.9 48.3 57.9 85.1 52.3 57.4 79.9 61.8 35.7 59.3 38.2 16.7 19.3 13.2 18.3 21.4 20.1 25.9 21.1 18.5 24.7 19.3 26.1 21.7 5.7 17.9 19.7 12.6 30.2 22.3 16.9 18.2 18.9 22.1 18.8 18.1 16.5 16.6 17.6 17.2 17.4 19.9 32.0 32.1 36.9 27.1 54.5 36.7 68.2 123.2 51.8 31.6 41.3 37.3 70.4 41.5 70.7 27.6 22.9 125.6 55.9 35.8 72.4 75.6 106.3 38.4 37.0 37.1 27.1 65.8 36.8 73.2 61.3 42.5 35.7 35.0 60.2 49.9 31.1 53.7 54.6 23.5 33.9 48.1 75.3 49.4 30.7 24.0 51.9 42.4 26.6 18.7 92.5 35.8 58.7 35.7 44.4 59.7 45.4 49.7 56.1 35.2 60.4 127.5 58.2 37.9 65.7 48.6 73.5 125.4 56.4 47.1 37.5 124.9 55.9 63.3 59.1 62.2 PNKD "BRP17, DKFZp564N1362, DYT8, FKSG19, FPD1, KIAA1184, KIPP1184, MGC31943, MR-1, MR-1S, PDC, PKND1, TAHCCP2" ENSG00000127838 "PNKD metallo-beta-lactamase domain containing" Q8N490 2 218270392-218346793 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 508.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010134, HPA017068" Approved Enhanced Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA010134: AB_1079645, HPA017068: AB_1855495" "unprognostic (3.15e-3)" "unprognostic (1.80e-2)" "unprognostic (5.86e-3)" "unprognostic (1.89e-2)" "unprognostic (1.90e-1)" "unprognostic (1.60e-1)" "unprognostic (3.81e-2)" "unprognostic (1.54e-1)" "unprognostic (1.37e-1)" "unprognostic (7.51e-2)" "unprognostic (3.29e-1)" "unprognostic (7.67e-2)" "prognostic unfavorable (5.13e-5)" "unprognostic (7.98e-2)" "unprognostic (2.17e-1)" "unprognostic (9.61e-2)" "unprognostic (1.44e-3)" 50.9 88.9 127.6 33.3 134.7 35.4 49.7 131.2 168.4 62.8 129.3 74.7 40.6 45.6 77.3 40.5 60.6 41.6 98.4 127.8 137.5 106.5 191.5 55.5 40.9 133.9 130.9 47.1 46.1 93.4 49.5 46.9 134.1 87.4 54.7 26.7 60.6 55.3 85.1 44.9 51.1 36.4 128.7 58.7 81.6 45.6 137.8 45.8 90.0 93.6 37.6 64.2 45.4 134.7 53.2 68.3 49.1 77.0 72.2 60.6 90.0 32.7 70.3 76.1 85.0 112.9 51.2 61.7 63.7 55.0 83.5 53.6 95.4 61.4 52.9 128.0 119.4 90.0 119.5 169.4 78.7 58.9 38.6 83.0 59.8 51.9 15.0 51.0 83.2 48.0 67.8 78.3 68.4 152.2 77.6 139.5 49.0 121.3 69.3 75.1 49.5 51.8 88.3 79.2 47.4 39.9 23.6 156.9 94.6 52.0 52.4 56.4 51.5 31.4 53.7 37.5 45.5 32.4 35.7 69.0 79.9 95.8 38.8 142.4 111.4 151.9 97.7 114.3 94.2 223.1 105.7 117.7 106.4 187.2 116.4 111.2 31.3 136.2 109.4 99.0 150.0 132.2 127.6 134.7 131.2 168.4 127.8 137.5 133.9 130.9 134.1 128.7 137.8 134.7 84.5 70.5 91.2 30.0 58.2 55.2 91.5 179.2 82.6 54.5 130.1 162.4 154.5 128.7 127.8 196.8 6.2 172.9 48.2 292.0 508.7 70.6 13.5 125.9 116.5 66.9 121.3 56.3 44.9 49.8 105.3 88.5 99.9 114.1 57.1 97.0 83.2 250.4 136.7 35.3 47.4 186.3 187.2 85.3 59.6 16.5 103.2 66.2 136.9 20.6 79.6 168.8 51.5 19.6 32.8 37.7 143.6 124.1 74.6 93.4 162.7 326.7 148.5 41.6 92.1 60.0 128.6 42.5 50.6 113.9 62.4 77.3 52.5 97.2 228.1 117.5 PTCD3 "DKFZp666K071, FLJ20758" ENSG00000132300 "Pentatricopeptide repeat domain 3" Q96EY7 2 86106223-86142157 "Predicted intracellular proteins, Ribosomal proteins" "Translation regulation" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041154, HPA041382" Supported Supported Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 52: Non-specific - Transcription" Mitochondria "HPA041154: AB_10795488, HPA041382: AB_10795695" "unprognostic (1.16e-2)" "unprognostic (4.47e-2)" "unprognostic (1.37e-2)" "unprognostic (9.30e-3)" "unprognostic (2.40e-2)" "unprognostic (2.54e-1)" "unprognostic (4.92e-3)" "unprognostic (2.06e-2)" "unprognostic (4.78e-2)" "unprognostic (3.78e-1)" "unprognostic (7.42e-3)" "unprognostic (5.49e-3)" "unprognostic (1.26e-1)" "prognostic favorable (6.77e-4)" "unprognostic (3.69e-1)" "unprognostic (7.79e-2)" "prognostic favorable (6.86e-4)" 10.0 15.8 13.1 7.6 14.2 14.7 9.9 15.2 15.9 11.6 16.3 12.6 10.1 11.7 10.2 10.7 11.7 6.4 26.2 13.3 14.5 12.4 16.5 9.6 11.8 13.6 14.0 15.1 10.7 13.1 14.8 9.2 14.7 10.4 13.5 13.2 9.8 7.5 32.8 10.3 11.9 9.0 13.7 12.0 11.8 16.6 13.5 10.5 12.0 36.3 11.1 10.3 10.7 16.7 16.2 37.6 22.0 18.5 16.1 16.6 26.2 32.6 13.8 18.0 18.0 69.9 15.1 39.7 11.8 17.1 18.6 28.9 44.7 17.7 22.9 17.8 37.0 31.8 23.0 59.2 16.3 26.0 23.1 19.8 12.8 13.7 24.4 18.8 15.7 28.6 33.5 14.8 16.0 15.0 21.7 31.0 20.2 31.5 23.9 28.8 30.9 30.6 24.6 31.7 23.9 14.7 15.2 25.0 30.4 20.6 13.2 15.7 11.3 14.2 15.1 14.6 19.2 33.7 47.6 31.6 13.8 29.4 11.1 4.4 9.6 7.6 12.4 7.0 14.6 15.3 11.2 13.2 10.6 16.4 15.1 11.3 0.3 14.3 14.1 10.7 13.9 8.8 13.1 14.2 15.2 15.9 13.3 14.5 13.6 14.0 14.7 13.7 13.5 16.7 17.1 57.7 33.5 50.3 31.0 26.0 26.3 27.7 34.7 61.7 19.2 16.8 105.7 18.6 37.4 23.9 66.7 53.0 30.6 21.7 25.4 18.8 34.8 27.5 33.3 23.5 31.1 39.5 52.9 11.9 27.0 30.5 30.1 24.2 33.6 47.5 21.4 41.7 21.7 37.0 53.1 25.3 20.3 19.6 13.3 22.4 27.1 17.7 8.8 21.5 22.7 49.8 28.8 48.7 53.4 15.0 19.2 19.5 26.4 23.7 23.2 30.1 26.2 65.3 13.1 36.3 21.3 98.3 62.4 28.7 24.7 36.7 31.8 47.9 38.5 20.4 PTPMT1 "DUSP23, MOSP, PLIP" ENSG00000110536 "Protein tyrosine phosphatase mitochondrial 1" Q8WUK0 11 47565430-47573461 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 235.1;Late spermatids: 640.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043932, HPA060060" Approved Enhanced Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 71: Testis - DNA repair" "Cluster 6: T47d - Mammary gland" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "HPA043932: AB_2678738, HPA060060: " "unprognostic (6.61e-2)" "unprognostic (2.09e-1)" "unprognostic (1.28e-1)" "unprognostic (2.37e-3)" "unprognostic (1.02e-1)" "unprognostic (1.26e-2)" "prognostic unfavorable (3.04e-5)" "unprognostic (3.29e-2)" "unprognostic (2.77e-2)" "unprognostic (1.93e-3)" "unprognostic (6.76e-2)" "unprognostic (1.72e-1)" "unprognostic (2.68e-3)" "unprognostic (1.21e-1)" "unprognostic (5.39e-1)" "unprognostic (2.17e-2)" "unprognostic (1.75e-1)" 38.8 56.5 15.0 5.3 16.1 9.0 37.4 15.8 17.4 31.1 16.6 31.0 7.6 32.8 7.8 34.8 29.5 4.2 27.7 14.4 16.5 37.6 40.6 36.5 6.1 15.6 16.3 28.0 44.7 9.6 41.9 6.7 15.8 32.7 3.9 4.2 37.1 5.9 41.0 28.1 23.4 4.7 16.0 28.9 39.2 105.4 17.0 4.3 30.6 5.8 4.9 27.5 28.1 16.0 34.5 19.4 2.3 17.8 17.5 11.4 7.0 20.1 17.1 19.4 16.8 27.9 17.6 27.9 22.1 14.7 16.8 30.6 16.9 20.4 16.6 31.4 57.3 12.9 43.8 43.4 25.7 25.2 17.1 12.7 21.9 8.8 24.0 11.2 13.7 26.2 32.6 19.5 14.2 65.4 21.4 41.0 18.8 3.9 37.7 38.6 16.7 22.3 22.5 23.3 15.5 21.4 33.8 11.1 23.2 7.2 53.1 32.7 16.6 13.6 23.3 28.6 33.1 27.1 22.6 18.6 13.6 23.3 10.0 11.2 38.0 38.2 24.8 36.8 23.0 33.7 22.7 26.2 44.9 30.3 22.3 21.0 3.1 26.1 34.6 64.6 28.5 28.8 15.0 16.1 15.8 17.4 14.4 16.5 15.6 16.3 15.8 16.0 17.0 16.0 26.8 22.4 35.0 14.4 31.8 17.8 15.8 58.5 34.1 14.4 64.9 78.4 5.8 45.8 38.6 40.5 4.2 72.2 34.7 19.9 72.4 95.3 235.1 48.0 23.9 24.6 31.3 30.1 8.2 85.8 66.3 23.9 28.1 25.6 17.1 16.5 29.6 39.8 62.4 5.0 10.8 45.7 48.8 32.6 21.2 640.8 46.6 45.6 46.2 6.5 56.2 74.9 41.2 9.5 14.6 106.2 38.8 46.6 61.0 26.0 37.9 72.8 57.2 15.7 19.7 17.3 28.1 179.8 28.6 55.0 17.3 76.8 25.9 21.3 62.7 22.0 RMDN3 "FAM82A2, FAM82C, FLJ10579, PTPIP51, RMD3" ENSG00000137824 "Regulator of microtubule dynamics 3" Q96TC7 15 40735884-40755851 "Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Differentiation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 110.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009975, HPA074840" Supported Enhanced "Cytokinetic bridge,Mitochondria" Yes No 42000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 45: Intestine - Brush border" "Cluster 39: CACO-2 - Unknown function" "Cluster 4: Macrophages - Innate immune response" Mitochondria "Cytokinetic bridge" "HPA009975: AB_1078811, HPA074840: " "unprognostic (2.54e-2)" "unprognostic (3.53e-1)" "unprognostic (2.35e-2)" "unprognostic (3.97e-3)" "unprognostic (1.50e-1)" "unprognostic (2.50e-3)" "unprognostic (2.78e-2)" "unprognostic (2.54e-2)" "unprognostic (1.73e-1)" "unprognostic (1.68e-1)" "unprognostic (2.78e-2)" "unprognostic (5.94e-3)" "prognostic favorable (6.70e-8)" "unprognostic (1.71e-2)" "unprognostic (1.32e-1)" "unprognostic (5.79e-3)" "unprognostic (2.04e-3)" 30.1 22.7 37.2 16.2 40.2 24.1 26.7 38.4 48.6 18.0 31.2 18.1 43.8 15.9 5.4 22.6 18.8 16.7 16.4 36.3 36.1 18.4 37.0 36.5 15.6 40.2 38.6 17.2 27.2 36.3 10.9 19.4 36.0 17.2 9.0 6.7 33.3 15.4 20.7 21.1 51.7 11.2 37.7 13.0 21.5 13.8 42.9 15.0 19.9 14.1 8.4 20.3 17.6 41.2 19.7 17.7 21.0 35.9 19.2 17.2 36.3 50.2 19.8 34.9 25.6 63.7 21.7 16.7 65.0 27.0 26.0 66.3 26.9 37.3 3.7 44.2 33.1 53.6 51.4 31.6 62.9 36.4 41.1 30.9 34.0 25.2 23.9 16.3 24.8 32.6 57.4 44.9 15.1 40.0 27.7 23.6 16.7 52.7 34.6 42.6 25.1 38.9 28.8 32.7 49.8 18.1 39.9 53.4 19.5 8.2 41.6 39.1 37.3 37.8 27.0 51.1 42.5 34.0 42.7 26.7 26.8 38.2 42.2 4.0 13.2 5.5 28.2 17.8 25.0 16.0 20.6 26.0 14.4 13.7 15.9 17.3 2.1 65.1 22.3 54.2 20.3 26.6 37.2 40.2 38.4 48.6 36.3 36.1 40.2 38.6 36.0 37.7 42.9 41.2 20.1 32.1 28.1 18.6 11.0 15.7 16.4 26.9 15.9 20.0 21.0 13.6 8.1 15.7 27.8 18.4 4.2 44.4 22.4 17.2 1.9 27.7 2.8 20.7 17.8 18.1 4.9 42.7 23.5 22.0 28.5 17.8 13.7 22.0 19.0 8.6 17.5 36.4 110.7 18.5 18.2 12.3 26.4 14.7 10.4 3.4 16.8 21.0 19.6 8.4 11.7 21.6 43.3 16.1 21.8 21.8 16.7 14.3 18.0 17.3 77.6 14.5 29.3 17.3 6.6 22.2 16.0 40.4 40.4 21.9 11.9 62.8 18.3 16.7 21.4 23.1 SDHA "FP, SDH2, SDHF" ENSG00000073578 "Succinate dehydrogenase complex flavoprotein subunit A" P31040 5 218241-257082 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Electron transport, Transport, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Cardiomyopathy, Disease variant, FDA approved drug targets, Leigh syndrome, Primary mitochondrial disease, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 601.0;skeletal muscle: 479.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB034929, HPA041981, HPA064582" Enhanced Supported Nucleoli,Mitochondria No No 360000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoli "CAB034929: AB_2183443, HPA041981: AB_2677779, HPA064582: AB_2685293" "prognostic unfavorable (6.00e-4)" "unprognostic (1.93e-1)" "unprognostic (5.97e-2)" "unprognostic (1.36e-1)" "unprognostic (1.89e-1)" "unprognostic (1.62e-1)" "unprognostic (2.80e-1)" "unprognostic (3.14e-2)" "unprognostic (2.88e-1)" "unprognostic (1.67e-2)" "unprognostic (1.97e-1)" "unprognostic (1.24e-1)" "prognostic favorable (9.53e-8)" "unprognostic (1.11e-2)" "unprognostic (2.62e-1)" "unprognostic (3.57e-1)" "unprognostic (1.79e-1)" 70.6 148.0 60.5 29.6 62.7 38.4 65.8 78.7 71.3 50.2 63.2 131.9 148.9 53.2 27.3 67.1 50.3 33.9 601.0 60.8 73.4 139.1 276.8 54.3 43.1 74.1 62.7 65.8 71.5 122.9 44.8 28.8 75.7 46.3 82.1 42.7 66.8 35.6 479.0 58.9 116.8 36.1 61.7 66.4 115.6 56.4 71.7 41.8 49.6 224.8 36.5 63.2 56.3 63.7 88.4 154.2 54.8 95.0 96.9 68.5 154.1 63.3 81.8 107.2 108.4 163.9 115.9 108.3 218.6 70.2 92.1 111.8 102.4 129.7 66.3 241.9 98.9 50.1 390.8 224.1 60.0 69.5 70.7 70.6 84.3 83.6 33.7 93.6 123.9 83.5 84.6 83.1 48.7 155.8 93.9 206.9 19.3 101.4 193.5 119.0 84.6 223.2 245.4 122.7 62.3 35.4 332.5 205.5 90.7 36.1 115.0 93.2 91.1 80.3 82.1 48.2 52.5 93.0 40.9 79.8 81.6 99.9 52.5 66.6 70.8 88.1 95.2 85.7 86.8 79.5 92.5 94.5 93.3 73.3 89.2 85.0 14.1 85.5 74.7 59.5 149.3 111.3 60.5 62.7 78.7 71.3 60.8 73.4 74.1 62.7 75.7 61.7 71.7 63.7 29.4 35.3 71.1 20.2 50.9 61.2 81.4 105.8 31.3 51.0 24.6 17.0 272.6 64.3 78.5 75.4 102.2 109.6 39.3 169.7 142.8 94.7 58.7 39.1 30.1 39.1 47.5 56.8 34.4 44.9 102.8 49.4 47.9 48.5 43.7 64.8 47.5 167.0 67.5 101.0 39.9 96.3 105.8 41.0 55.0 28.8 68.3 38.8 90.7 12.2 60.2 50.7 52.5 19.1 37.9 54.2 100.1 55.7 67.5 37.0 274.4 190.7 75.2 87.2 78.9 33.2 51.7 96.9 54.3 40.9 35.9 154.7 56.7 85.0 160.1 88.2 SFXN1 "FLJ12876, SLC56A1" ENSG00000164466 "Sideroflexin 1" Q9H9B4 5 175477062-175529742 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, One-carbon metabolism, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 99.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 99.8" "Group enriched" "Detected in all" 5 "granulocytes: 99.8;T-cells: 36.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019543, HPA063745" Approved Enhanced Mitochondria NA NA 23000 "Cluster 46: Basophils - DNA binding" "Cluster 85: Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 58: T-cells - T-cell receptor" Mitochondria "HPA019543: AB_1856789, HPA063745: AB_2685111" "unprognostic (4.77e-3)" "unprognostic (5.26e-2)" "unprognostic (1.54e-2)" "unprognostic (3.62e-3)" "unprognostic (2.35e-1)" "unprognostic (1.30e-2)" "unprognostic (3.59e-2)" "unprognostic (8.58e-3)" "unprognostic (2.47e-2)" "unprognostic (1.17e-2)" "unprognostic (2.48e-2)" "unprognostic (1.51e-1)" "unprognostic (1.31e-1)" "unprognostic (7.30e-2)" "unprognostic (4.98e-1)" "unprognostic (1.08e-3)" "unprognostic (4.23e-2)" 7.6 15.4 14.0 18.2 14.8 21.9 8.1 15.0 17.4 9.3 15.0 28.1 19.3 8.5 8.0 14.7 8.7 9.8 12.3 13.3 15.3 41.6 99.7 5.9 27.0 12.1 12.6 18.7 13.1 15.8 12.9 15.3 13.2 9.6 17.7 20.7 9.6 10.4 10.9 8.8 20.1 11.3 13.0 10.5 14.6 6.6 13.8 24.0 10.5 15.7 27.0 13.8 11.2 14.8 39.9 123.1 61.7 67.0 21.0 44.4 99.2 99.1 41.5 81.3 78.3 156.5 77.6 82.3 74.9 51.9 100.4 49.7 119.0 171.9 87.8 202.1 102.4 60.6 103.4 69.0 30.3 119.6 73.3 36.5 33.1 90.3 39.2 48.3 63.3 74.9 89.1 63.4 60.2 138.3 140.3 9.7 48.7 66.5 41.1 116.3 63.1 87.8 31.3 154.2 104.6 66.7 95.6 88.9 47.8 50.5 43.1 38.3 62.3 63.9 100.3 47.5 130.2 80.2 101.8 184.6 105.1 104.9 68.1 99.8 5.1 26.3 26.2 6.7 21.4 10.7 36.4 29.2 7.3 9.3 28.4 29.3 1.6 12.7 4.3 3.5 32.3 14.2 14.0 14.8 15.0 17.4 13.3 15.3 12.1 12.6 13.2 13.0 13.8 14.8 6.0 3.2 13.5 55.2 29.1 19.5 33.5 30.6 48.9 59.3 13.7 9.9 18.1 17.2 18.8 18.4 47.9 41.4 19.0 68.9 25.4 27.7 1.2 10.9 23.3 14.2 31.2 45.4 77.3 18.7 74.2 24.8 26.0 11.3 9.5 38.1 12.8 98.7 17.2 77.4 62.9 23.9 26.4 8.1 11.4 4.0 47.2 9.5 10.6 30.9 9.0 19.8 37.0 55.3 60.1 31.8 20.1 35.0 63.4 31.6 89.8 51.1 15.5 49.9 26.3 21.7 23.1 2.8 7.4 43.6 21.6 30.9 61.9 67.2 21.7 27.0 SFXN3 "SFX3, SLC56A3" ENSG00000107819 "Sideroflexin 3" Q9BWM7 10 101031234-101041244 "Metabolic proteins, Predicted membrane proteins" "Amino-acid transport, One-carbon metabolism, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 177.5;Proximal enterocytes: 119.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008028, HPA048105" Approved Enhanced Mitochondria NA NA "Cluster 46: Basophils - DNA binding" "Cluster 45: Intestine - Brush border" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "HPA008028: AB_1079938, HPA048105: AB_2680265" "unprognostic (2.55e-1)" "unprognostic (3.32e-2)" "unprognostic (4.94e-2)" "unprognostic (2.82e-2)" "unprognostic (4.94e-3)" "prognostic unfavorable (3.79e-4)" "unprognostic (3.84e-3)" "unprognostic (8.46e-2)" "unprognostic (1.05e-2)" "unprognostic (9.09e-3)" "unprognostic (1.04e-3)" "unprognostic (1.48e-1)" "prognostic unfavorable (4.94e-4)" "unprognostic (3.56e-1)" "unprognostic (3.05e-2)" "unprognostic (3.70e-2)" "unprognostic (1.71e-1)" 20.1 10.7 16.2 11.8 19.0 6.2 14.9 19.4 21.2 17.9 15.7 13.9 31.7 18.0 21.5 8.1 18.3 16.4 15.1 19.7 12.9 12.0 4.3 21.3 7.9 18.5 15.8 12.7 9.1 18.3 9.0 21.0 19.2 12.0 10.4 23.4 11.1 16.5 3.6 22.2 37.5 25.4 12.7 10.7 11.0 7.2 18.2 6.4 9.9 7.9 7.1 14.9 14.7 19.3 44.4 16.9 1.7 5.2 43.5 46.0 4.4 26.4 92.7 33.0 26.4 28.1 47.4 1.9 24.8 62.1 27.7 31.8 7.9 57.7 14.4 12.3 10.2 5.3 27.1 20.4 29.8 4.2 41.2 31.8 8.3 29.1 27.3 91.8 73.5 12.5 0.4 1.4 54.4 7.3 1.9 6.4 2.1 16.2 40.3 4.3 32.5 12.0 48.5 6.8 9.0 44.1 14.4 1.7 39.3 11.8 13.8 31.2 60.9 29.0 22.7 26.0 13.1 6.6 2.7 0.2 70.7 23.7 23.7 10.6 18.1 9.1 11.0 13.4 8.5 2.4 7.4 7.6 19.1 1.1 4.5 5.6 3.2 5.5 7.8 2.9 8.7 11.7 16.2 19.0 19.4 21.2 19.7 12.9 18.5 15.8 19.2 12.7 18.2 19.3 17.1 12.8 5.3 7.5 3.9 13.9 5.0 6.3 2.8 60.2 6.9 7.0 3.2 18.6 4.6 5.5 47.9 1.2 21.2 7.3 1.9 31.7 51.9 25.2 13.4 17.5 5.4 4.8 14.2 15.3 40.9 17.4 7.7 5.6 14.5 55.5 20.0 0.9 37.4 10.1 12.2 7.8 4.1 21.3 29.9 177.5 17.4 24.3 33.8 1.0 12.0 7.7 9.2 5.0 16.0 38.5 10.8 14.7 10.4 2.9 119.1 14.3 38.8 24.0 13.1 6.7 12.0 1.4 0.7 1.3 10.9 10.9 19.7 2.7 5.6 3.4 SLC25A24 "APC1, DKFZp586G0123" ENSG00000085491 "Solute carrier family 25 member 24" Q6NUK1 1 108134043-108200849 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Distal enterocytes: 126.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028519, HPA063636" Enhanced Enhanced Mitochondria NA NA 19000 "Cluster 7: Monocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA028519: AB_10603890, HPA063636: AB_2685068" "unprognostic (1.94e-2)" "unprognostic (7.30e-3)" "prognostic favorable (1.01e-4)" "unprognostic (7.11e-2)" "unprognostic (1.64e-2)" "unprognostic (2.91e-1)" "unprognostic (8.54e-4)" "unprognostic (1.51e-2)" "unprognostic (7.39e-2)" "unprognostic (1.29e-1)" "unprognostic (1.15e-3)" "unprognostic (6.18e-2)" "unprognostic (6.76e-2)" "unprognostic (2.21e-1)" "unprognostic (1.67e-1)" "unprognostic (1.03e-1)" "unprognostic (2.29e-1)" 10.0 6.2 0.8 5.3 0.7 3.8 8.2 0.6 1.3 12.5 0.8 13.5 11.4 6.6 3.2 6.0 6.7 6.8 4.9 0.7 0.8 6.3 1.6 9.1 5.1 0.8 0.7 5.9 4.2 8.2 2.8 9.4 0.9 4.0 16.0 6.7 6.7 4.6 3.7 4.3 12.3 8.7 0.6 5.7 6.9 3.2 1.0 5.0 7.1 4.5 4.9 10.1 7.0 0.7 38.2 8.9 28.8 8.6 17.9 23.4 11.4 13.0 17.0 25.1 27.4 11.3 12.9 0.0 10.3 28.7 10.9 14.1 7.9 24.0 35.1 7.9 4.4 2.4 13.4 5.2 14.9 6.1 4.9 17.6 17.0 15.0 18.5 16.8 19.6 5.7 6.2 13.0 32.2 28.7 3.7 1.4 14.3 17.3 8.1 5.7 33.9 12.6 16.9 22.8 5.0 8.7 17.4 14.9 17.5 27.5 13.3 10.7 10.5 13.8 6.2 23.2 15.0 3.0 2.3 0.0 5.0 11.8 8.2 0.4 0.5 0.4 0.3 0.5 0.3 0.1 0.2 0.2 0.4 0.4 0.1 0.3 0.1 0.2 0.7 0.3 0.4 0.1 0.8 0.7 0.6 1.3 0.7 0.8 0.8 0.7 0.9 0.6 1.0 0.7 33.9 54.5 27.8 5.5 24.2 15.6 20.4 20.6 17.1 14.7 25.5 16.8 15.5 17.2 33.5 18.4 8.4 7.1 16.3 126.7 21.5 31.2 3.2 62.0 46.7 28.6 18.1 6.7 18.0 36.9 60.2 23.2 40.2 61.7 22.2 20.9 29.6 1.2 54.1 10.1 14.9 43.2 18.3 51.8 32.8 2.9 19.6 50.0 23.2 16.9 44.7 12.7 11.3 14.6 20.8 67.6 51.2 18.0 9.7 14.3 54.4 24.9 55.2 33.9 52.6 27.2 26.5 6.2 2.4 24.8 14.9 6.2 23.9 41.8 59.1 33.8 SLC25A31 "ANT4, DKFZP434N1235" ENSG00000151475 "Solute carrier family 25 member 31" Q9H0C2 4 127730400-127774292 "Predicted membrane proteins, Transporters" "Antiport, Differentiation, Spermatogenesis, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 272 "testis: 47.3" "Cell type enriched" "Detected in some" 8 "Spermatocytes: 198.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015064, HPA016841, HPA046835, HPA071684" Uncertain Enhanced Mitochondria NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "HPA015064: AB_1847691, HPA016841: AB_1847690, HPA046835: AB_2679831, HPA071684: AB_2686431" "unprognostic (8.15e-2)" "unprognostic (1.62e-1)" "unprognostic (2.70e-1)" "unprognostic (5.32e-1)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 13.5 3.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 198.2 23.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SOD2 GClnc1 ENSG00000112096 "Superoxide dismutase 2" P04179 6 159669069-159762529 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 1083.7;skeletal muscle: 3230.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 2508.2;Prostatic glandular cells: 3524.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 10 "neutrophil: 4470.5" "Lineage enriched" "Detected in all" 10 "granulocytes: 4470.5" "Cell line enhanced" "Detected in all" "BJ hTERT+: 1611.9;GAMG: 614.3;HSkMC: 688.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001814, CAB002013" Supported Enhanced Mitochondria NA NA 55000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" Mitochondria "CAB002013: , HPA001814: AB_1080134" "unprognostic (2.47e-2)" "unprognostic (2.77e-3)" "unprognostic (1.14e-1)" "unprognostic (1.57e-2)" "unprognostic (1.31e-1)" "unprognostic (1.69e-1)" "unprognostic (1.49e-1)" "unprognostic (3.10e-2)" "unprognostic (1.37e-1)" "unprognostic (6.67e-2)" "unprognostic (2.76e-2)" "unprognostic (7.14e-2)" "prognostic unfavorable (1.72e-4)" "unprognostic (8.12e-2)" "unprognostic (4.14e-2)" "unprognostic (5.99e-2)" "unprognostic (1.82e-1)" 324.8 245.9 66.8 522.8 43.2 1083.7 169.0 37.8 125.8 92.6 99.7 126.4 60.5 105.4 7.2 136.5 118.5 121.8 178.5 37.0 101.0 252.4 459.8 266.5 64.8 250.0 96.1 55.8 212.3 69.1 42.7 62.9 192.9 130.8 37.9 25.1 328.8 43.9 3230.1 90.0 83.7 108.4 62.5 81.4 120.4 39.6 153.1 38.2 67.2 312.6 65.0 514.9 97.9 85.4 35.8 46.3 37.3 85.1 229.0 378.7 20.5 52.7 1611.9 57.7 131.1 91.3 19.4 70.7 144.5 54.1 614.3 58.9 39.1 42.5 42.4 71.2 87.2 74.5 71.8 152.3 169.5 74.0 31.9 688.9 68.5 180.9 133.6 40.7 30.0 44.9 106.7 82.2 55.4 37.6 60.3 46.6 63.3 41.5 55.4 79.6 50.3 63.9 106.2 56.6 71.5 29.5 105.1 52.4 21.4 14.1 33.1 33.7 30.4 168.6 62.1 92.5 87.9 37.8 100.2 86.5 186.7 57.4 23.6 146.3 364.4 181.1 38.8 273.9 43.4 43.4 54.9 38.5 105.2 38.3 45.0 36.9 4470.5 19.1 445.3 14.8 87.9 340.0 66.8 43.2 37.8 125.8 37.0 101.0 250.0 96.1 192.9 62.5 153.1 85.4 303.2 201.9 746.1 13.4 99.0 684.7 1144.9 2508.2 114.4 45.6 150.2 96.6 0.0 287.4 613.3 237.3 45.9 18.3 43.8 153.9 86.1 1400.2 318.2 281.7 649.8 593.0 79.6 101.2 31.1 1389.7 51.2 1098.4 103.5 1080.1 112.3 23.1 58.9 395.0 292.0 32.0 30.1 92.7 339.7 333.3 1425.8 111.5 58.1 1031.2 521.2 15.9 339.9 50.4 35.0 8.5 12.2 581.6 111.3 65.1 101.2 3524.0 128.6 530.1 269.6 61.8 39.5 1164.0 407.3 91.7 51.4 258.7 681.8 27.2 119.4 38.3 148.1 1195.7 SUCLA2 LINC00444 ENSG00000136143 "Succinate-CoA ligase ADP-forming subunit beta" Q9P2R7 13 47745736-48037968 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Ligase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 232.2;tongue: 271.9" "Cell type enhanced" "Detected in all" "Early spermatids: 256.2;Late spermatids: 314.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039435, HPA039536, HPA061528" Enhanced Supported Enhanced Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA039435: AB_10673144, HPA039536: AB_2676561, HPA061528: AB_2684553" "unprognostic (5.66e-3)" "unprognostic (1.72e-2)" "unprognostic (1.14e-1)" "unprognostic (8.76e-2)" "unprognostic (1.60e-1)" "unprognostic (3.45e-2)" "unprognostic (2.48e-1)" "unprognostic (1.71e-1)" "unprognostic (4.70e-2)" "unprognostic (1.41e-2)" "unprognostic (1.10e-1)" "unprognostic (1.38e-1)" "prognostic favorable (7.59e-14)" "unprognostic (3.53e-1)" "unprognostic (2.19e-1)" "unprognostic (2.29e-1)" "prognostic unfavorable (1.22e-4)" 53.9 40.6 28.4 20.2 30.8 13.6 38.7 36.6 39.2 32.4 33.6 37.1 58.2 27.2 24.8 33.1 24.7 20.3 100.2 30.7 38.2 77.5 29.0 18.2 22.0 30.6 30.0 30.9 25.4 71.2 20.4 28.1 32.3 35.8 36.3 44.2 33.9 31.3 232.2 20.5 44.7 33.1 30.6 19.9 29.7 17.9 33.8 30.7 36.4 271.9 23.9 26.0 25.3 35.1 44.9 49.5 60.6 37.1 68.4 51.3 38.9 64.8 72.4 66.9 44.5 91.3 47.9 61.3 49.3 63.9 39.9 60.0 81.9 61.9 81.6 59.8 75.9 69.2 45.8 58.0 47.6 69.9 38.9 48.4 71.2 45.3 52.6 54.4 49.0 70.7 47.7 21.1 65.8 31.4 73.1 80.8 64.4 150.2 64.7 60.9 55.4 49.3 94.4 41.9 34.7 41.2 54.5 49.3 39.1 66.5 43.8 60.8 39.0 36.2 24.1 53.0 45.7 23.0 37.4 72.7 22.8 50.9 54.8 12.6 50.2 27.8 34.4 53.7 41.9 34.6 38.0 42.2 62.5 33.1 47.7 47.5 8.8 51.8 46.1 49.8 46.6 36.5 28.4 30.8 36.6 39.2 30.7 38.2 30.6 30.0 32.3 30.6 33.8 35.1 20.8 25.6 16.8 17.6 20.1 32.4 37.7 57.5 21.1 44.8 28.9 26.5 148.8 17.2 40.2 31.3 12.5 48.7 18.1 29.1 164.4 32.3 256.2 50.9 32.0 22.0 19.2 21.0 37.0 17.8 42.7 37.7 19.9 52.6 33.7 25.2 16.1 14.7 29.9 45.4 39.0 19.5 71.2 16.7 20.4 314.2 37.0 21.7 42.7 21.5 24.9 43.3 13.4 26.2 38.2 20.2 30.6 46.3 22.1 35.9 62.3 127.4 29.9 42.4 39.5 33.3 50.0 36.3 29.0 22.8 31.7 52.1 19.7 47.3 30.4 39.0 TACO1 CCDC44 ENSG00000136463 "Translational activator of cytochrome c oxidase I" Q9BSH4 17 63600882-63608365 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Translation regulation" Activator "Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 69.2" "Cell type enhanced" "Detected in all" "Hepatocytes: 87.9;Proximal enterocytes: 81.2;Proximal tubular cells: 109.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021626, HPA021643, HPA024294" Enhanced Enhanced Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA021626: AB_1846148, HPA021643: AB_1846149, HPA024294: AB_1846150" "unprognostic (1.26e-1)" "unprognostic (2.92e-2)" "unprognostic (4.55e-3)" "unprognostic (9.82e-2)" "unprognostic (1.30e-1)" "unprognostic (9.30e-3)" "unprognostic (2.83e-1)" "unprognostic (8.09e-2)" "unprognostic (2.09e-1)" "unprognostic (7.38e-2)" "prognostic favorable (3.73e-4)" "unprognostic (1.35e-1)" "unprognostic (4.12e-3)" "unprognostic (5.21e-3)" "unprognostic (1.13e-1)" "unprognostic (1.51e-1)" "unprognostic (1.60e-2)" 12.8 18.6 16.6 8.2 17.4 8.3 10.9 18.9 18.4 8.8 17.7 17.8 18.9 11.1 9.7 13.4 9.3 5.5 42.3 16.5 17.5 30.1 69.2 7.7 10.4 17.4 17.4 8.3 12.0 18.2 9.5 8.3 17.3 9.5 16.1 9.4 11.4 9.2 61.5 11.3 16.7 9.7 16.9 11.5 15.1 12.1 17.6 9.9 9.4 55.9 12.2 11.8 9.2 16.7 39.6 61.2 19.4 20.2 16.5 23.5 25.7 28.5 26.8 56.2 44.4 40.5 23.2 32.6 21.2 33.1 38.9 35.8 43.0 41.5 52.6 17.3 58.1 32.0 29.8 72.3 45.5 38.3 21.7 29.0 28.6 48.5 51.1 20.9 29.6 24.2 44.4 24.1 26.6 71.6 44.7 28.7 16.8 42.5 62.9 28.1 47.7 40.8 33.2 27.6 29.5 32.4 19.6 64.0 55.3 25.3 53.3 29.1 26.4 39.9 29.9 27.5 50.7 25.9 27.2 38.7 30.4 26.0 29.6 2.2 9.4 9.0 9.8 8.5 10.7 7.5 13.7 9.7 10.6 9.9 12.4 10.3 1.4 17.8 7.4 7.0 10.2 9.4 16.6 17.4 18.9 18.4 16.5 17.5 17.4 17.4 17.3 16.9 17.6 16.7 9.8 3.2 6.3 2.6 12.0 2.5 8.0 21.1 8.6 8.2 7.8 10.9 54.0 17.2 11.5 14.7 2.1 32.1 8.2 32.9 54.8 29.1 15.3 8.0 11.4 14.2 13.8 17.4 4.0 27.4 28.9 14.1 16.8 6.4 9.5 16.2 8.6 87.9 26.3 6.7 3.9 21.7 12.2 10.7 3.9 46.0 11.8 9.2 10.6 2.8 22.0 15.5 14.4 1.5 3.2 30.0 25.8 11.3 10.7 11.6 81.2 109.7 9.1 13.4 19.7 10.7 14.6 26.8 13.9 18.6 4.3 19.8 10.1 40.7 32.8 7.1 TBRG4 "Cpr2, FASTKD4, H_TD2522F11.8, KIAA0948" ENSG00000136270 "Transforming growth factor beta regulator 4" Q969Z0 7 45100100-45112047 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020582, HPA050430" Approved Enhanced Mitochondria NA NA 23000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA020582: AB_1857804, HPA050430: AB_2681125" "unprognostic (2.22e-1)" "unprognostic (4.75e-2)" "unprognostic (1.19e-1)" "unprognostic (3.46e-3)" "unprognostic (1.41e-2)" "unprognostic (9.29e-3)" "prognostic unfavorable (1.40e-4)" "unprognostic (3.15e-2)" "unprognostic (1.86e-1)" "unprognostic (2.83e-1)" "unprognostic (4.53e-1)" "unprognostic (1.25e-2)" "unprognostic (3.66e-3)" "unprognostic (3.91e-2)" "unprognostic (3.84e-2)" "unprognostic (3.30e-1)" "unprognostic (1.52e-1)" 24.5 29.5 19.3 23.0 21.8 23.0 24.0 22.8 21.4 22.9 23.5 36.1 29.4 23.1 7.9 35.8 21.2 11.9 56.5 19.7 21.6 29.6 43.3 19.0 25.5 22.4 21.1 24.0 21.3 21.9 17.4 19.5 23.0 24.5 18.7 6.6 24.1 15.6 83.0 32.4 28.6 15.6 21.4 28.5 26.2 34.4 22.0 21.9 18.9 66.2 17.9 29.3 25.5 23.2 49.4 113.1 35.7 77.3 31.5 28.9 70.2 39.2 35.9 74.6 61.5 123.8 67.5 93.8 58.7 39.9 103.3 125.6 82.6 89.3 37.6 49.0 77.8 64.5 73.6 84.4 51.6 74.5 63.4 39.7 81.7 71.2 50.7 26.7 46.6 79.3 181.1 46.0 46.2 84.5 75.9 168.0 111.0 110.6 88.6 65.9 45.3 136.2 44.1 50.4 69.9 65.6 40.4 218.8 77.6 45.6 97.7 120.4 36.4 54.6 65.7 33.9 64.8 81.0 87.6 137.5 50.1 104.9 125.7 17.3 23.8 20.6 31.1 44.3 29.5 27.9 25.6 30.0 35.9 20.9 34.5 33.3 1.9 18.1 39.5 13.6 27.2 33.0 19.3 21.8 22.8 21.4 19.7 21.6 22.4 21.1 23.0 21.4 22.0 23.2 13.3 3.2 16.3 9.4 21.0 35.1 33.2 39.8 15.4 15.1 17.0 15.0 28.0 15.7 24.1 20.2 0.0 61.5 18.4 32.9 43.0 31.1 24.6 12.5 13.8 14.2 22.2 14.3 6.5 18.3 72.5 17.9 24.5 16.9 14.0 25.4 10.4 31.8 34.5 11.8 7.1 32.5 36.7 12.3 17.8 19.6 16.4 18.0 17.8 3.7 34.6 14.7 14.4 4.5 8.4 29.5 28.0 11.7 17.9 33.8 33.5 47.4 11.2 14.2 13.1 17.1 25.5 72.4 33.0 17.0 29.3 47.9 19.2 44.7 53.3 30.2 TEFM "C17orf42, FLJ22729" ENSG00000172171 "Transcription elongation factor, mitochondrial" Q96QE5 17 30897336-30906238 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023788, HPA053044" Approved Enhanced Mitochondria No No "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Mitochondria "HPA023788: AB_1848818, HPA053044: AB_2682023" "unprognostic (1.22e-1)" "unprognostic (1.18e-2)" "unprognostic (1.11e-3)" "unprognostic (3.31e-2)" "unprognostic (7.89e-2)" "unprognostic (3.75e-1)" "prognostic unfavorable (9.20e-4)" "unprognostic (1.25e-1)" "prognostic unfavorable (8.64e-4)" "unprognostic (2.11e-1)" "unprognostic (6.18e-3)" "unprognostic (9.39e-2)" "unprognostic (4.79e-2)" "unprognostic (7.90e-2)" "unprognostic (1.92e-1)" "unprognostic (2.23e-1)" "unprognostic (8.37e-3)" 4.9 6.0 4.4 5.9 4.6 2.2 6.7 5.7 6.0 4.0 5.5 5.7 5.6 4.9 4.1 5.2 4.8 4.1 8.9 4.6 4.4 9.6 8.8 4.0 7.3 4.5 4.4 4.8 3.3 6.6 3.2 6.8 4.6 5.0 6.6 6.9 5.4 4.8 6.8 5.3 4.6 5.1 4.3 5.7 5.1 4.2 4.6 5.4 5.4 11.7 6.7 5.4 2.9 5.1 12.8 19.2 10.7 14.9 12.7 12.4 10.1 13.1 9.5 23.7 21.4 15.6 7.2 17.4 12.7 8.1 15.5 21.6 18.6 9.1 22.4 5.5 23.9 8.8 15.1 15.5 8.5 18.7 11.2 7.9 11.7 13.4 6.9 7.2 11.9 12.4 19.1 14.3 13.9 11.7 16.0 24.3 8.9 19.6 12.1 10.5 22.9 17.6 19.2 14.4 16.3 7.5 9.8 11.7 15.4 10.9 23.7 14.1 7.8 10.9 14.7 11.2 13.8 7.9 14.0 16.2 7.3 13.8 13.2 2.6 7.7 6.5 6.4 12.2 8.8 9.8 8.2 6.5 8.1 6.3 9.9 9.2 2.3 8.6 9.9 7.0 10.0 7.1 4.4 4.6 5.7 6.0 4.6 4.4 4.5 4.4 4.6 4.3 4.6 5.1 10.1 16.0 10.6 13.7 11.3 4.1 8.0 22.6 9.1 17.8 6.8 6.9 5.8 11.5 13.6 9.2 8.4 26.0 11.5 5.4 25.4 13.4 10.4 12.6 15.3 9.6 5.4 6.9 27.1 8.5 17.3 10.2 5.1 7.8 5.1 17.2 10.4 10.1 20.4 16.8 27.3 7.4 22.4 7.8 3.0 6.3 8.1 9.6 7.2 21.5 14.0 15.0 16.5 27.2 32.2 12.5 5.6 7.5 7.1 5.2 9.4 17.7 17.8 19.4 19.7 11.0 11.6 27.7 17.8 8.7 4.3 17.8 10.0 18.9 7.9 4.7 TFAM "TCF6, TCF6L2" ENSG00000108064 "Transcription factor A, mitochondrial" Q00059 10 58385345-58399220 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 7 "Early spermatids: 631.4;Late spermatids: 933.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040648, HPA063684" Supported Enhanced Mitochondria "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 34: Spermatids - Unknown function" Mitochondria "HPA040648: AB_10795635, HPA063684: AB_2685089" "unprognostic (5.30e-2)" "unprognostic (1.14e-1)" "unprognostic (6.34e-3)" "prognostic unfavorable (8.73e-4)" "unprognostic (1.10e-2)" "unprognostic (3.40e-2)" "unprognostic (1.54e-2)" "unprognostic (3.23e-2)" "unprognostic (1.24e-2)" "prognostic favorable (2.74e-4)" "unprognostic (1.99e-2)" "unprognostic (5.39e-2)" "prognostic favorable (2.22e-5)" "unprognostic (1.31e-1)" "unprognostic (2.24e-1)" "unprognostic (1.79e-1)" "unprognostic (6.76e-2)" 16.5 20.1 5.7 21.6 6.1 38.1 17.3 10.8 8.4 11.4 6.8 20.0 21.0 13.7 9.5 14.7 12.6 10.7 18.5 5.5 7.3 21.5 22.6 10.9 27.7 5.8 6.1 17.8 13.9 16.2 6.3 20.4 6.5 14.5 17.3 9.8 17.3 11.4 17.7 9.0 17.8 11.6 7.0 17.3 16.1 33.0 6.4 24.9 19.6 16.1 23.0 16.7 7.5 8.8 85.7 47.7 52.8 54.7 15.3 19.4 59.8 37.9 37.3 46.8 51.1 170.0 88.6 170.1 53.9 17.6 34.8 65.2 97.6 53.5 73.4 73.4 85.7 64.1 33.4 64.5 23.3 164.7 49.4 19.2 24.4 57.0 51.6 22.2 41.1 49.9 153.4 74.8 33.2 46.4 130.2 65.1 100.0 39.2 49.9 102.9 113.0 76.0 28.3 57.0 69.8 48.1 75.1 103.7 97.0 42.9 112.8 47.9 32.0 34.4 109.5 39.5 102.5 75.6 125.8 214.2 44.1 125.1 26.4 1.0 9.5 4.0 8.3 9.5 10.8 12.8 10.0 8.8 12.1 12.5 12.4 10.1 7.1 15.0 8.3 14.7 9.0 6.9 5.7 6.1 10.8 8.4 5.5 7.3 5.8 6.1 6.5 7.0 6.4 8.8 46.4 54.5 27.9 6.2 52.5 50.1 44.0 52.4 59.2 25.1 48.6 62.9 35.0 38.6 51.0 20.2 16.7 98.1 56.8 17.1 88.0 41.0 631.4 36.8 44.5 39.5 15.5 46.7 10.1 44.7 77.4 38.8 25.0 41.2 29.7 34.1 26.0 64.1 44.0 38.7 11.5 37.5 18.3 21.9 19.3 933.1 41.3 32.3 23.2 2.8 36.3 38.2 48.4 10.6 11.7 35.2 23.0 30.9 35.8 47.3 14.1 72.0 31.4 21.4 26.3 74.8 40.5 55.3 63.9 48.6 54.7 52.5 38.3 69.1 48.1 31.8 TFB2M "FLJ22661, FLJ23182, Hkp1" ENSG00000162851 "Transcription factor B2, mitochondrial" Q9H5Q4 1 246540561-246566261 "Metabolic proteins, Predicted intracellular proteins" "rRNA processing, Transcription, Transcription regulation" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028482, HPA028554, HPA030265" Approved Enhanced Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA028482: AB_2672633, HPA028554: AB_2732441, HPA030265: AB_10696209" "unprognostic (4.38e-2)" "unprognostic (2.45e-2)" "unprognostic (3.79e-3)" "unprognostic (5.63e-2)" "unprognostic (1.10e-1)" "unprognostic (8.13e-2)" "unprognostic (8.76e-2)" "unprognostic (1.41e-1)" "unprognostic (2.51e-2)" "unprognostic (1.68e-2)" "unprognostic (2.46e-1)" "unprognostic (6.81e-2)" "unprognostic (5.26e-2)" "unprognostic (2.27e-1)" "unprognostic (9.44e-2)" "unprognostic (6.41e-2)" "unprognostic (3.53e-2)" 11.6 23.5 3.6 9.4 3.7 24.2 12.1 6.2 5.0 8.5 6.3 12.6 11.4 7.2 9.5 10.9 8.6 7.1 14.0 3.4 3.9 21.2 37.8 6.3 13.3 3.4 3.5 6.9 15.6 10.8 6.3 9.1 3.5 8.8 12.9 5.0 11.3 7.5 22.7 9.3 9.1 8.0 3.8 7.0 10.1 8.7 3.9 9.3 13.6 24.3 13.2 13.3 6.1 4.1 33.9 31.9 12.1 21.5 14.8 21.1 42.2 24.2 24.8 26.9 24.6 39.0 31.6 59.8 36.9 24.7 17.4 28.5 29.3 25.7 36.8 23.4 11.3 30.3 18.1 34.5 24.2 54.1 26.3 21.0 30.2 23.1 25.8 14.8 21.2 20.9 89.2 19.8 23.4 15.7 27.5 24.1 53.8 58.6 32.1 27.2 23.9 72.9 24.5 36.7 26.7 53.8 23.4 41.9 82.2 13.3 30.6 51.3 15.6 18.7 22.7 26.6 63.8 57.1 102.9 47.6 23.0 52.6 23.9 0.3 5.4 1.5 9.1 5.7 11.5 11.9 8.0 9.7 12.9 12.0 10.3 8.9 1.2 14.8 9.8 11.1 12.3 5.3 3.6 3.7 6.2 5.0 3.4 3.9 3.4 3.5 3.5 3.8 3.9 4.1 11.9 6.4 9.4 4.2 17.2 53.3 13.7 27.9 31.9 3.2 12.4 11.9 16.5 14.3 18.4 16.5 10.4 24.4 13.1 7.6 29.4 13.8 1.5 17.6 12.9 13.2 11.4 8.6 8.1 15.5 28.1 10.2 18.8 22.4 14.0 7.5 5.7 33.9 11.9 0.0 7.2 14.3 6.1 9.3 7.7 3.4 6.5 7.3 5.4 1.9 6.9 6.6 7.2 6.0 5.5 11.0 10.3 4.5 12.7 17.2 7.8 39.2 15.4 3.4 13.1 14.4 12.2 13.2 21.6 21.3 44.9 21.1 10.9 17.7 19.8 10.4 TIMM10 "TIM10, TIM10A, TIMM10A" ENSG00000134809 "Translocase of inner mitochondrial membrane 10" P62072 11 57528464-57530803 "Predicted intracellular proteins" "Protein transport, Translocation, Transport" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 284.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039946 Supported Enhanced Mitochondria NA NA 16000 "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA039946: AB_10673023" "unprognostic (9.34e-3)" "unprognostic (1.16e-2)" "unprognostic (2.21e-1)" "unprognostic (2.01e-1)" "unprognostic (4.42e-2)" "unprognostic (1.25e-2)" "unprognostic (2.74e-1)" "unprognostic (1.39e-1)" "unprognostic (2.07e-1)" "unprognostic (3.40e-3)" "unprognostic (7.62e-2)" "unprognostic (1.18e-1)" "unprognostic (5.96e-2)" "unprognostic (9.87e-2)" "unprognostic (1.96e-1)" "unprognostic (1.62e-2)" "unprognostic (2.15e-2)" 40.5 41.6 55.1 28.5 56.9 34.8 42.5 56.3 68.3 24.8 53.2 35.5 27.0 27.2 43.8 44.1 25.1 20.3 60.9 56.7 57.4 50.7 77.6 27.9 45.8 55.8 55.6 25.5 33.6 45.1 29.2 21.7 56.1 31.0 35.9 15.1 28.0 30.2 77.8 33.7 27.8 27.5 58.5 37.9 35.3 35.6 56.1 38.5 29.7 67.7 50.1 33.7 27.2 58.0 115.6 171.9 79.1 76.0 67.6 57.2 99.7 96.6 77.0 151.1 85.9 127.6 97.9 218.1 108.0 86.5 131.4 86.3 114.0 112.6 136.4 74.8 84.9 139.4 67.0 167.5 71.3 183.3 148.0 54.2 89.6 146.1 101.4 40.0 95.2 142.8 157.1 96.7 112.7 241.1 99.4 243.5 83.4 99.9 184.4 163.5 167.0 190.3 77.6 78.2 64.0 82.2 101.5 198.6 128.6 77.7 150.1 69.3 60.2 86.0 160.5 150.6 188.1 133.2 192.6 176.1 79.2 91.3 146.2 30.9 88.3 20.9 71.5 84.2 81.6 187.6 86.4 79.0 146.4 179.0 118.0 103.6 4.9 67.3 81.3 146.6 84.0 145.1 55.1 56.9 56.3 68.3 56.7 57.4 55.8 55.6 56.1 58.5 56.1 58.0 53.2 12.8 11.0 3.9 66.4 122.9 42.9 94.5 54.1 16.9 103.1 142.2 124.1 78.6 45.6 44.1 4.2 68.0 52.5 78.2 211.3 84.1 134.7 36.7 28.1 55.8 27.0 56.8 3.2 125.6 88.2 42.0 24.5 39.1 52.6 30.1 40.4 212.3 125.9 8.4 3.9 61.0 48.8 71.7 100.3 284.7 46.3 52.9 81.8 3.7 103.2 55.0 56.7 3.0 5.6 85.3 63.5 51.1 51.5 102.4 120.3 227.3 23.2 15.5 13.1 50.5 71.3 85.9 52.8 78.1 129.7 39.5 42.2 37.7 92.6 52.4 TIMM17A "TIM17, TIM17A" ENSG00000134375 "Translocase of inner mitochondrial membrane 17A" Q99595 1 201955503-201970664 "Cancer-related genes, Predicted membrane proteins" "Protein transport, Translocation, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 265.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010083 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Mitochondria" "HPA010083: AB_10602899" "prognostic unfavorable (1.98e-5)" "unprognostic (3.28e-1)" "unprognostic (1.32e-1)" "unprognostic (1.09e-1)" "unprognostic (1.14e-1)" "unprognostic (1.80e-3)" "unprognostic (7.58e-2)" "unprognostic (4.15e-2)" "unprognostic (7.45e-2)" "unprognostic (1.64e-2)" "unprognostic (8.54e-3)" "unprognostic (2.02e-2)" "unprognostic (2.01e-1)" "unprognostic (6.45e-3)" "unprognostic (1.21e-1)" "unprognostic (1.44e-2)" "unprognostic (2.81e-1)" 31.4 48.3 29.3 35.4 30.6 36.8 29.3 31.2 35.8 27.4 34.9 35.2 31.4 25.7 41.1 31.9 20.9 19.0 72.2 31.3 32.5 42.2 80.6 23.7 30.9 30.2 30.6 18.5 23.4 55.8 24.8 31.3 31.0 25.0 38.0 33.3 23.0 28.4 86.1 20.9 23.9 35.3 30.5 24.9 29.1 19.7 30.7 30.3 38.2 94.9 35.8 42.8 23.2 29.4 89.1 88.9 78.5 94.9 64.5 67.2 132.5 138.4 98.0 110.5 98.4 104.8 89.7 122.5 49.7 118.6 81.1 69.2 145.3 82.4 118.3 90.4 90.7 67.7 119.1 99.7 66.7 145.5 69.5 78.0 89.8 113.2 93.9 79.5 117.4 75.4 173.1 66.7 131.7 56.9 78.9 78.3 99.6 88.3 47.0 76.5 91.4 152.6 136.2 83.1 118.0 83.2 84.6 213.5 130.7 98.7 118.5 97.0 95.2 73.6 78.7 86.7 146.4 99.9 115.9 102.3 78.4 109.2 84.2 18.5 32.0 29.2 21.7 44.5 28.6 30.3 23.5 28.1 50.1 23.6 22.4 26.2 7.7 29.7 46.7 33.6 37.0 32.2 29.3 30.6 31.2 35.8 31.3 32.5 30.2 30.6 31.0 30.5 30.7 29.4 31.7 38.5 37.2 9.4 54.7 92.2 100.2 123.3 34.1 24.1 43.2 36.2 129.5 37.1 73.0 38.6 35.5 115.2 44.2 38.8 137.0 94.5 69.7 40.1 55.2 46.0 34.0 36.6 18.1 86.0 187.0 55.9 40.2 48.1 55.2 37.9 32.9 168.0 114.8 35.3 17.4 58.1 81.4 44.0 177.7 32.0 33.5 52.8 53.4 4.7 80.4 49.4 26.8 6.6 14.9 109.4 30.4 38.4 98.6 85.0 37.2 131.8 55.8 31.7 26.3 46.6 75.3 42.6 61.5 60.6 98.9 265.6 46.2 62.9 58.3 118.1 TIMM44 TIM44 ENSG00000104980 "Translocase of inner mitochondrial membrane 44" O43615 19 7926718-7943667 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043052, HPA073108" Supported Enhanced Mitochondria NA NA 9100 "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA043052: AB_10795713, HPA073108: " "unprognostic (1.75e-1)" "unprognostic (7.44e-3)" "unprognostic (2.68e-2)" "unprognostic (1.03e-1)" "unprognostic (1.24e-1)" "unprognostic (1.45e-2)" "unprognostic (5.81e-3)" "unprognostic (8.78e-2)" "unprognostic (2.42e-1)" "unprognostic (8.81e-2)" "unprognostic (2.07e-3)" "unprognostic (8.93e-2)" "unprognostic (1.80e-2)" "unprognostic (6.01e-2)" "unprognostic (6.43e-2)" "unprognostic (2.07e-2)" "unprognostic (4.18e-2)" 15.2 25.1 16.1 11.2 15.2 8.4 13.0 15.9 22.8 20.2 16.3 27.6 16.9 18.3 7.0 20.9 13.9 6.8 52.3 15.8 15.4 20.0 34.6 10.7 11.1 15.4 15.2 16.2 17.6 13.5 14.4 8.3 15.6 17.5 8.2 4.2 14.0 11.6 62.1 15.7 14.3 10.2 16.6 19.4 20.8 11.0 17.6 7.7 13.8 49.2 8.1 20.1 15.3 16.2 64.5 37.2 24.4 52.0 28.6 28.6 33.3 34.9 26.6 43.8 39.6 82.5 18.1 98.5 45.5 27.5 37.3 46.6 75.7 38.4 21.7 45.5 98.7 53.6 31.4 70.1 72.4 66.3 21.9 31.6 60.1 37.0 53.5 19.4 30.4 53.3 97.2 55.7 20.7 58.5 59.2 53.7 61.3 61.8 116.8 60.4 35.6 68.8 24.9 42.0 46.2 28.3 39.0 50.5 112.8 19.3 29.7 64.4 19.6 30.1 40.2 69.7 72.5 70.4 84.8 99.5 24.2 92.7 48.6 14.3 12.9 4.1 11.3 14.1 10.4 8.6 11.0 10.9 16.4 7.9 9.9 10.6 1.1 10.3 8.7 12.5 9.8 9.5 16.1 15.2 15.9 22.8 15.8 15.4 15.4 15.2 15.6 16.6 17.6 16.2 20.0 35.3 16.4 13.7 31.8 27.9 33.7 41.9 14.2 53.0 43.8 37.6 36.1 32.9 21.5 29.5 41.7 38.5 25.6 48.4 66.5 47.8 11.7 24.8 42.1 22.2 40.1 28.2 13.5 42.9 43.2 25.4 19.4 31.6 33.0 26.4 20.3 62.2 34.9 52.2 13.9 45.5 26.4 21.7 11.1 13.7 36.7 17.2 21.4 1.9 22.9 23.5 44.3 11.1 10.9 42.1 29.0 29.3 25.8 31.8 45.9 75.1 12.4 63.6 32.9 25.0 33.7 38.7 33.9 18.7 19.9 32.6 20.2 29.5 64.6 30.9 TIMMDC1 "C3orf1, FLJ22597" ENSG00000113845 "Translocase of inner mitochondrial membrane domain containing 1" Q9NPL8 3 119498547-119525090 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053214, HPA055846" Uncertain Enhanced Nucleoplasm,Mitochondria NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 28: BEWO - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoplasm "HPA053214: AB_2682081, HPA055846: AB_2682941" "unprognostic (3.95e-2)" "unprognostic (8.85e-2)" "unprognostic (1.73e-1)" "unprognostic (2.53e-2)" "unprognostic (2.88e-1)" "unprognostic (1.60e-1)" "prognostic unfavorable (1.12e-5)" "unprognostic (9.60e-2)" "unprognostic (6.25e-2)" "unprognostic (3.39e-1)" "unprognostic (4.67e-3)" "unprognostic (1.05e-1)" "unprognostic (3.87e-2)" "unprognostic (8.89e-2)" "unprognostic (1.31e-1)" "unprognostic (2.76e-1)" "unprognostic (1.05e-1)" 10.5 12.0 13.4 10.7 14.3 6.3 13.1 14.2 15.4 15.0 13.2 11.3 8.9 9.3 17.9 15.9 12.8 14.4 44.0 12.7 13.9 17.8 14.2 11.0 17.7 14.3 13.6 10.9 11.1 23.1 7.1 17.1 13.9 13.0 13.7 4.2 14.6 19.7 27.3 15.8 7.7 12.1 14.0 9.9 8.5 10.6 14.1 11.4 19.1 49.2 14.8 14.2 7.0 14.6 26.9 24.5 12.4 10.4 45.5 30.6 27.0 7.7 25.3 21.7 24.7 16.7 16.0 19.5 13.7 27.1 15.1 12.2 30.8 24.8 35.0 16.4 10.9 14.4 10.7 18.8 23.9 11.3 9.1 28.0 37.4 18.4 22.4 13.9 31.5 18.5 19.8 18.1 40.3 33.2 12.0 23.7 16.2 22.4 30.1 10.0 8.4 25.4 32.0 13.1 15.8 29.4 7.8 11.8 28.0 16.2 19.5 30.4 16.1 12.2 9.3 11.3 13.8 12.1 11.8 28.3 20.7 28.5 19.6 11.1 17.6 21.3 10.8 17.6 12.5 16.2 10.4 12.0 17.4 17.6 12.2 10.9 4.3 13.1 20.9 15.1 20.7 22.1 13.4 14.3 14.2 15.4 12.7 13.9 14.3 13.6 13.9 14.0 14.1 14.6 61.2 25.6 39.3 18.6 24.0 37.5 50.4 110.2 31.3 25.0 44.8 55.0 165.3 41.5 63.7 40.5 14.6 157.5 28.9 44.0 150.6 73.2 12.2 39.9 41.1 56.0 28.8 43.1 17.4 62.7 112.7 48.2 29.0 31.1 41.2 34.1 31.8 52.4 86.3 21.9 23.9 43.5 87.5 32.7 40.4 10.0 47.2 39.4 44.4 15.0 65.7 73.6 18.6 22.6 35.6 52.7 40.9 54.5 30.2 43.5 50.5 146.5 63.0 35.4 72.3 43.9 52.5 111.1 58.2 45.9 42.1 177.5 29.7 48.0 45.7 46.7 TMEM71 FLJ33069 ENSG00000165071 "Transmembrane protein 71" Q6P5X7 8 132685007-132760712 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 33.5;heart muscle: 37.1" "Cell type enhanced" "Detected in many" "dendritic cells: 39.9;Kupffer cells: 20.7;Langerhans cells: 25.7;Macrophages: 26.2;monocytes: 25.5;NK-cells: 54.6;T-cells: 35.9" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 4 "cerebral cortex: 9.7" "Immune cell enhanced" "Detected in all" "neutrophil: 269.0" "Lineage enriched" "Detected in all" 5 "granulocytes: 269.0" "Cell line enhanced" "Detected in many" "BJ hTERT+: 12.7;HDLM-2: 54.5;Karpas-707: 11.1;U-937: 31.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA058401, HPA070655" Uncertain Enhanced Mitochondria NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Mitochondria "HPA058401: AB_2683707, HPA070655: AB_2686292" "unprognostic (1.39e-3)" "unprognostic (7.27e-2)" "unprognostic (8.82e-2)" "unprognostic (3.10e-3)" "unprognostic (7.94e-2)" "unprognostic (3.91e-3)" "unprognostic (4.18e-2)" "unprognostic (5.06e-2)" "unprognostic (1.53e-1)" "unprognostic (1.71e-1)" "unprognostic (1.63e-1)" "unprognostic (1.62e-1)" "unprognostic (8.83e-2)" "unprognostic (1.90e-2)" "unprognostic (6.29e-3)" "unprognostic (4.39e-2)" "unprognostic (2.73e-1)" 5.6 2.0 1.0 13.1 1.3 33.5 8.5 1.0 9.7 2.5 2.2 11.3 2.2 1.3 1.1 2.8 1.9 5.5 37.1 1.1 1.8 2.6 3.9 8.2 13.2 1.6 1.3 1.0 2.4 0.7 1.1 1.8 2.1 2.0 3.4 0.5 5.7 2.2 1.6 1.1 7.3 3.6 1.1 18.4 2.8 1.0 2.4 19.2 2.0 4.6 10.6 4.6 1.9 1.6 0.4 0.0 4.9 0.0 0.0 0.0 0.0 1.3 12.7 0.5 0.9 0.0 0.0 0.1 0.6 4.1 0.1 0.0 0.0 0.3 1.5 54.5 0.0 0.0 0.0 0.0 0.3 3.6 0.0 0.1 0.0 0.1 2.0 1.4 1.0 6.7 0.0 11.1 2.4 0.0 2.9 2.2 1.2 0.0 0.4 0.1 1.8 0.8 4.8 0.1 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.1 2.1 0.5 0.9 1.2 5.7 0.1 2.9 0.0 9.0 31.6 3.7 61.9 55.9 101.6 31.3 16.1 57.9 6.6 22.8 22.2 33.7 4.7 33.9 25.1 269.0 12.9 14.7 1.1 3.0 39.0 1.0 1.3 1.0 9.7 1.1 1.8 1.6 1.3 2.1 1.1 2.4 1.6 0.5 0.0 3.0 0.0 6.9 0.9 1.0 2.5 0.6 0.0 4.2 2.7 15.9 0.0 5.5 0.0 0.0 0.0 39.9 0.1 0.0 0.0 6.5 0.1 0.3 1.5 0.0 8.8 0.5 0.0 0.0 4.1 1.1 0.2 1.3 0.0 3.3 0.2 3.2 0.0 1.3 0.2 0.0 20.7 25.7 5.1 0.0 26.2 5.4 17.8 25.5 1.9 54.6 0.0 0.1 0.1 0.0 0.0 11.3 0.1 0.0 0.4 2.9 0.0 0.0 3.7 0.8 0.0 0.6 0.4 0.3 0.3 35.9 0.1 0.0 4.5 TNRC18 "CAGL79, KIAA1856, TNRC18A" ENSG00000182095 "Trinucleotide repeat containing 18" O15417 7 5306790-5425414 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 20.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020730, HPA024251" Uncertain Supported "Nucleoplasm,Nuclear membrane,Mitochondria,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Nuclear membrane, Mitochondria" Cytosol "HPA020730: AB_2670506, HPA024251: AB_2671498" "unprognostic (1.66e-1)" "unprognostic (3.17e-3)" "unprognostic (2.67e-3)" "unprognostic (4.44e-1)" "unprognostic (1.81e-1)" "unprognostic (6.67e-2)" "unprognostic (1.13e-2)" "unprognostic (1.79e-1)" "unprognostic (3.01e-1)" "unprognostic (2.11e-2)" "unprognostic (6.08e-2)" "unprognostic (1.36e-1)" "unprognostic (9.29e-3)" "unprognostic (2.14e-1)" "unprognostic (2.94e-1)" "unprognostic (1.02e-1)" "unprognostic (4.34e-2)" 30.4 18.3 10.8 29.0 8.9 51.8 30.1 16.2 14.2 40.8 2.2 56.3 25.3 57.6 16.4 26.0 43.5 22.4 22.1 10.3 0.5 22.9 19.8 32.0 16.1 6.2 1.7 46.0 29.5 35.0 22.2 30.6 1.6 36.1 22.6 12.2 28.8 34.3 24.0 33.2 29.0 36.4 1.3 25.2 33.8 22.6 5.1 17.2 32.6 11.1 14.6 40.8 31.9 3.2 72.8 63.4 51.5 43.4 42.9 50.6 133.8 50.4 47.3 27.4 29.0 26.3 62.4 49.3 48.3 74.7 60.8 79.7 30.2 60.5 23.0 21.6 19.2 31.4 56.6 43.1 37.1 104.3 111.2 51.2 70.0 54.8 63.2 39.5 31.3 43.6 45.4 27.2 35.3 120.0 24.6 127.2 4.5 47.5 48.0 27.0 25.7 37.3 22.3 91.3 22.3 53.4 38.8 102.5 37.0 23.1 106.9 106.1 78.7 78.3 109.6 47.0 36.7 38.6 44.1 46.2 44.1 72.6 94.1 14.2 3.8 3.6 1.7 1.5 1.2 2.2 1.2 1.0 1.4 2.3 0.9 1.7 20.8 3.2 2.1 5.4 1.9 0.2 10.8 8.9 16.2 14.2 10.3 0.5 6.2 1.7 1.6 1.3 5.1 3.2 25.6 9.6 29.0 59.7 7.4 9.3 3.7 9.8 13.6 51.7 15.8 25.9 7.5 14.3 12.4 14.7 2.1 14.5 20.4 33.6 1.9 5.0 14.4 22.2 29.7 17.3 31.3 9.7 40.9 6.6 3.8 17.8 19.4 36.2 14.0 48.3 29.6 25.4 11.2 50.5 45.6 30.4 8.2 41.8 12.4 18.8 18.3 22.8 5.4 71.2 25.9 31.0 11.3 32.6 20.3 9.0 10.6 19.9 12.1 6.5 7.4 5.4 11.1 4.0 19.7 18.4 21.2 0.4 2.1 12.5 8.8 10.0 12.3 18.6 25.1 3.8 TOMM20 "KIAA0016, MAS20, MOM19, TOM20" ENSG00000173726 "Translocase of outer mitochondrial membrane 20" Q15388 1 235109341-235128837 "Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005585, HPA011562" Supported Enhanced Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 32: Non-specific - Translation" Mitochondria "CAB005585: AB_628381, HPA011562: AB_1080326" "unprognostic (1.30e-1)" "unprognostic (3.08e-3)" "unprognostic (1.66e-2)" "unprognostic (4.49e-2)" "unprognostic (8.65e-3)" "unprognostic (1.17e-2)" "unprognostic (7.09e-2)" "unprognostic (3.28e-1)" "unprognostic (3.18e-2)" "unprognostic (1.75e-1)" "unprognostic (1.16e-3)" "unprognostic (5.05e-2)" "unprognostic (7.08e-3)" "unprognostic (2.33e-2)" "unprognostic (1.17e-1)" "unprognostic (1.11e-1)" "unprognostic (3.97e-1)" 71.5 83.5 80.0 39.2 89.0 96.6 130.8 63.0 111.9 82.9 63.4 64.3 61.0 83.5 91.6 67.8 95.6 48.3 86.4 91.7 79.9 100.4 88.3 60.2 53.7 76.9 71.5 119.5 103.1 111.6 54.3 68.2 81.2 80.5 67.9 51.3 125.1 70.1 83.0 82.5 54.5 59.3 81.7 47.2 69.4 32.8 84.1 57.1 142.9 82.4 56.6 66.4 56.7 83.3 198.7 102.4 131.6 111.6 101.4 202.6 203.5 138.8 119.3 127.9 92.5 133.1 135.6 239.3 180.1 121.0 36.1 154.0 147.8 135.0 166.9 57.9 314.8 146.2 126.2 253.9 169.2 331.3 84.2 182.3 180.8 128.6 175.4 173.0 140.7 92.2 312.1 85.9 141.9 58.2 141.9 149.4 296.6 131.2 54.9 170.9 100.3 312.6 144.5 140.2 172.5 402.8 108.0 149.2 306.7 53.6 230.9 358.6 125.6 111.5 67.5 143.0 299.6 201.2 203.1 172.4 131.2 155.4 193.1 37.7 18.8 6.5 19.4 19.7 23.6 23.0 24.8 24.3 22.7 18.2 30.1 24.2 5.6 15.8 22.9 30.6 23.7 21.5 80.0 89.0 63.0 111.9 91.7 79.9 76.9 71.5 81.2 81.7 84.1 83.3 167.2 137.8 163.5 25.1 201.9 267.4 254.9 158.5 251.6 49.9 299.2 307.0 137.8 160.2 151.3 49.7 29.2 171.3 195.5 98.3 160.4 161.6 318.4 180.2 254.3 156.8 160.5 127.0 69.0 211.2 462.5 139.9 121.3 216.9 157.7 146.4 129.9 160.1 159.9 50.5 61.1 273.4 99.7 197.7 164.6 354.0 155.0 175.7 149.4 28.1 187.5 145.4 116.4 26.2 55.8 220.1 172.3 153.4 176.7 340.4 247.0 223.5 99.7 60.9 105.2 201.4 207.5 186.5 71.1 273.3 286.1 199.5 179.5 196.1 272.6 333.4 TOMM22 TOM22 ENSG00000100216 "Translocase of outer mitochondrial membrane 22" Q9NS69 22 38681957-38685421 "Predicted membrane proteins" "Protein transport, Translocation, Transport" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003037 Supported Enhanced Mitochondria NA NA 230000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA003037: AB_1080329" "unprognostic (5.54e-2)" "unprognostic (5.04e-3)" "unprognostic (2.74e-3)" "unprognostic (1.48e-2)" "unprognostic (1.32e-1)" "unprognostic (1.85e-2)" "prognostic unfavorable (2.90e-5)" "unprognostic (1.01e-1)" "unprognostic (4.28e-1)" "unprognostic (7.01e-2)" "unprognostic (1.64e-2)" "unprognostic (7.39e-2)" "unprognostic (5.44e-2)" "unprognostic (5.32e-2)" "unprognostic (1.99e-1)" "unprognostic (7.86e-2)" "unprognostic (1.64e-1)" 19.6 21.1 27.6 19.0 28.5 30.4 17.2 29.0 29.7 16.6 29.4 22.6 24.5 15.5 19.2 28.4 20.5 11.5 29.1 27.7 28.7 23.9 28.5 12.7 25.3 28.6 28.2 19.1 21.1 22.5 9.9 15.7 28.9 15.1 27.6 8.6 21.4 12.5 34.6 22.1 19.4 19.4 28.0 17.0 20.3 17.0 29.6 27.0 17.1 31.0 30.5 23.8 17.8 28.3 61.7 35.5 53.4 56.9 38.6 35.7 57.5 49.7 34.3 71.1 53.1 65.0 35.8 62.0 39.9 48.9 48.7 49.7 81.8 75.2 56.7 53.8 89.9 83.4 25.2 63.0 50.2 223.2 56.7 49.0 52.6 64.1 41.6 37.0 52.9 59.5 64.4 48.2 48.1 47.9 67.7 103.3 82.0 80.8 71.5 73.9 69.2 58.8 47.7 44.3 62.4 41.3 58.1 72.7 59.1 36.1 50.5 73.1 54.3 43.4 81.8 40.1 76.2 65.9 85.7 94.3 54.3 76.0 60.6 12.9 50.9 16.6 35.4 51.1 44.9 48.7 37.8 37.5 66.4 37.8 38.0 41.4 5.0 42.7 43.1 58.0 48.7 72.8 27.6 28.5 29.0 29.7 27.7 28.7 28.6 28.2 28.9 28.0 29.6 28.3 62.4 25.6 30.4 4.2 123.3 167.0 134.8 158.7 109.8 30.1 79.5 67.7 70.2 82.9 68.0 71.7 16.7 180.0 89.7 74.8 223.0 135.3 139.6 50.5 58.8 77.1 105.1 98.8 7.3 133.2 232.1 70.4 65.7 50.6 74.3 100.3 69.9 101.4 163.9 28.6 8.4 133.5 99.7 120.2 130.7 143.2 55.3 93.3 113.8 4.7 153.2 76.1 105.0 4.5 8.7 116.2 85.2 54.5 130.3 153.4 116.2 245.9 35.2 33.7 72.3 73.3 76.9 130.1 148.2 185.5 210.3 135.6 102.6 100.9 189.7 158.7 TOMM40 "C19orf1, D19S1177E, PER-EC1, PEREC1, TOM40" ENSG00000130204 "Translocase of outer mitochondrial membrane 40" O96008 19 44890569-44903689 "Predicted intracellular proteins, Transporters" "Ion transport, Protein transport, Transport" Porin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036231, HPA036232" Supported Enhanced Mitochondria,Cytosol NA NA 45000 "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Cytosol "HPA036231: AB_2675010, HPA036232: AB_2675011" "unprognostic (2.14e-1)" "unprognostic (9.58e-3)" "unprognostic (1.66e-1)" "unprognostic (6.75e-3)" "unprognostic (2.37e-1)" "unprognostic (2.17e-2)" "unprognostic (1.13e-3)" "unprognostic (1.13e-2)" "unprognostic (7.84e-2)" "unprognostic (1.20e-1)" "unprognostic (1.85e-2)" "unprognostic (1.35e-1)" "unprognostic (5.86e-3)" "unprognostic (5.30e-3)" "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" "unprognostic (2.87e-1)" 34.6 59.7 31.3 25.1 30.1 32.9 29.0 33.6 37.2 25.2 28.0 34.7 28.4 25.0 14.1 51.8 25.3 10.8 46.1 30.7 33.5 33.5 50.8 28.4 23.6 32.6 33.5 24.9 26.6 31.4 25.3 20.0 33.6 24.7 23.0 18.0 24.1 17.4 64.0 34.4 26.1 16.4 30.2 26.4 29.3 22.0 35.0 25.2 22.3 34.4 22.6 29.9 29.5 32.2 147.6 244.6 87.6 121.3 32.2 28.4 110.3 103.3 57.1 192.1 136.6 268.8 99.5 215.3 107.7 68.8 108.7 155.2 228.9 149.1 87.0 84.0 206.1 145.3 93.5 214.7 68.0 187.6 125.1 45.2 83.4 149.3 94.1 36.0 67.3 102.4 232.6 73.3 76.4 184.2 205.4 137.1 153.6 209.6 149.1 206.1 99.2 125.3 89.6 201.8 135.2 86.4 109.9 229.4 75.2 48.4 77.1 188.2 55.9 132.0 133.6 93.1 273.7 78.3 176.0 212.9 98.2 197.0 142.1 0.7 3.6 3.7 2.8 4.6 3.2 5.8 2.8 4.1 4.6 2.4 4.9 5.4 0.7 3.2 4.3 4.6 3.5 1.4 31.3 30.1 33.6 37.2 30.7 33.5 32.6 33.5 33.6 30.2 35.0 32.2 26.2 16.0 7.3 8.8 34.9 87.4 73.7 17.1 35.9 68.2 32.7 30.9 15.7 25.8 14.3 31.3 29.2 104.5 28.9 78.8 39.2 48.1 11.3 22.7 41.0 31.0 29.3 52.4 11.3 38.6 169.9 38.6 40.2 29.5 19.1 57.8 12.5 24.2 100.1 70.7 16.9 59.4 28.5 21.0 44.9 7.2 26.8 35.0 39.2 4.7 31.9 46.6 27.8 5.5 12.8 53.6 32.4 24.5 47.9 139.0 34.5 39.5 4.9 60.2 19.7 49.1 47.8 46.2 64.5 60.5 89.4 72.9 26.7 105.9 132.1 75.5 TOMM70 "KIAA0719, Tom70, TOMM70A" ENSG00000154174 "Translocase of outer mitochondrial membrane 70" O94826 3 100363431-100401089 "Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 34.9;Extravillous trophoblasts: 33.2;Proximal tubular cells: 48.6;Theca cells: 32.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014589, CAB017156, HPA048020" Enhanced Enhanced Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "CAB017156: , HPA014589: AB_1858185, HPA048020: AB_2680234" "unprognostic (2.74e-2)" "unprognostic (2.25e-1)" "unprognostic (2.57e-2)" "unprognostic (2.69e-3)" "unprognostic (2.12e-2)" "unprognostic (5.96e-2)" "unprognostic (2.06e-3)" "unprognostic (5.01e-2)" "unprognostic (9.86e-2)" "unprognostic (1.21e-1)" "unprognostic (9.73e-3)" "unprognostic (5.38e-2)" "unprognostic (2.62e-3)" "unprognostic (1.73e-1)" "unprognostic (3.53e-1)" "unprognostic (3.34e-2)" "unprognostic (6.98e-3)" 29.7 23.1 21.8 19.5 38.7 16.6 31.5 20.6 24.4 19.8 19.1 27.7 29.3 24.5 21.3 28.9 20.4 16.1 38.8 23.6 23.0 36.8 61.7 15.9 22.2 21.3 18.6 30.8 26.8 27.2 14.8 23.4 21.9 26.4 29.8 45.4 21.9 26.9 66.4 19.8 24.4 26.7 17.9 19.2 21.5 19.6 22.9 29.6 30.1 76.1 25.9 27.3 17.8 19.5 70.2 48.3 39.8 57.9 55.4 60.0 52.0 57.9 49.6 52.2 53.8 68.7 39.0 83.2 49.9 49.7 46.6 67.4 73.1 53.4 76.7 31.6 33.7 95.2 30.3 67.3 34.6 117.2 41.8 53.7 48.6 46.5 75.6 46.5 38.8 40.1 69.2 65.6 63.3 51.9 79.6 47.5 55.2 107.4 101.2 72.0 80.9 89.0 42.6 52.2 72.2 60.1 42.3 67.0 77.9 38.2 87.1 65.8 35.2 45.5 60.3 25.8 44.0 71.1 108.8 139.1 44.1 70.0 35.2 1.1 1.0 1.2 1.9 1.1 2.3 2.0 2.3 2.0 1.4 1.4 2.3 2.5 0.2 2.7 1.3 1.4 1.0 0.8 21.8 38.7 20.6 24.4 23.6 23.0 21.3 18.6 21.9 17.9 22.9 19.5 24.2 6.4 25.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 30.0 20.2 0.0 0.0 11.2 14.7 0.0 26.8 11.5 0.0 11.7 19.0 0.0 13.8 34.9 10.0 0.0 0.0 0.0 20.1 33.2 12.9 0.0 25.4 7.6 27.1 0.0 0.0 22.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 5.7 0.0 0.0 0.0 0.0 22.5 0.0 0.0 2.3 0.0 0.0 48.6 10.2 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.0 16.3 6.3 32.9 0.0 0.0 TRAP1 "HSP75, HSP90L" ENSG00000126602 "TNF receptor associated protein 1" Q12931 16 3651639-3717553 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 140.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041082, HPA044227" Enhanced Enhanced Mitochondria NA NA 1700000 "Cluster 27: Non-specific - Gene expression" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA041082: AB_2677291, HPA044227: AB_2678864" "unprognostic (1.18e-1)" "unprognostic (1.51e-1)" "prognostic favorable (1.80e-4)" "unprognostic (7.10e-2)" "unprognostic (6.80e-2)" "unprognostic (2.76e-2)" "unprognostic (1.52e-2)" "unprognostic (9.61e-2)" "unprognostic (8.58e-2)" "unprognostic (5.71e-3)" "unprognostic (1.54e-1)" "unprognostic (7.69e-3)" "unprognostic (1.01e-2)" "unprognostic (2.24e-2)" "unprognostic (6.68e-2)" "unprognostic (9.90e-2)" "unprognostic (3.82e-2)" 46.4 50.6 32.5 32.7 35.6 35.6 45.7 28.9 37.6 54.0 22.7 50.0 39.7 42.5 18.5 72.2 59.0 33.3 88.1 34.5 34.2 59.9 121.5 33.3 47.6 33.1 32.2 58.8 76.2 39.9 35.3 33.3 33.5 41.6 36.9 22.3 46.1 26.5 193.9 67.7 36.7 30.3 26.8 39.9 49.5 40.1 36.7 27.5 33.3 138.9 36.4 48.9 50.4 32.5 113.4 277.6 56.7 150.2 61.1 62.1 167.6 67.6 60.7 152.2 95.3 347.9 156.5 361.1 123.7 65.1 41.1 207.3 223.0 167.7 67.1 139.3 241.8 105.9 225.1 246.0 105.3 192.0 69.4 74.2 114.6 121.1 188.2 55.0 106.1 122.5 338.4 120.8 50.5 367.8 138.6 141.5 106.0 133.8 140.1 314.1 118.9 500.6 112.8 83.0 268.4 102.2 70.0 254.5 135.8 46.5 184.5 137.2 60.2 63.7 112.9 112.5 99.5 135.5 161.1 289.2 39.7 152.1 88.8 0.1 24.0 0.8 24.7 38.9 47.3 42.1 36.0 31.5 54.9 30.7 42.1 35.9 2.6 31.9 29.8 8.4 33.4 33.0 32.5 35.6 28.9 37.6 34.5 34.2 33.1 32.2 33.5 26.8 36.7 32.5 20.4 22.4 17.5 16.3 21.3 25.4 44.3 63.2 38.1 29.3 32.4 36.8 2.1 45.8 39.8 31.3 10.4 112.6 5.9 28.7 88.0 67.7 24.1 30.6 21.1 21.3 35.5 42.1 31.6 53.8 56.2 23.7 36.2 28.1 16.5 41.5 12.8 48.8 46.1 47.1 31.1 37.5 59.0 14.5 14.8 13.0 16.4 14.7 12.4 12.2 26.3 20.2 12.3 11.6 16.2 31.9 14.5 21.4 37.9 45.9 14.1 140.9 30.1 22.2 19.7 29.9 29.4 37.2 70.9 70.7 28.1 67.2 15.1 58.9 74.9 42.8 TTC19 "FLJ20343, MGC19520" ENSG00000011295 "Tetratricopeptide repeat domain 19" Q6DKK2 17 15999784-16045015 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Electron transport, Respiratory chain, Transport" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 5.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023010, HPA052380" Enhanced Enhanced Mitochondria "Intracellular and membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 52: Non-specific - Transcription" Mitochondria "HPA023010: AB_1858429, HPA052380: AB_2681806" "unprognostic (1.04e-2)" "unprognostic (4.90e-3)" "unprognostic (2.87e-2)" "unprognostic (4.80e-3)" "unprognostic (8.09e-2)" "unprognostic (2.86e-1)" "unprognostic (1.06e-2)" "unprognostic (2.84e-2)" "unprognostic (8.34e-2)" "unprognostic (1.72e-2)" "unprognostic (2.30e-3)" "unprognostic (5.14e-2)" "prognostic favorable (5.67e-4)" "unprognostic (1.31e-1)" "unprognostic (3.22e-1)" "unprognostic (4.85e-2)" "unprognostic (2.24e-1)" 6.6 11.4 8.1 3.8 7.8 11.2 7.5 19.4 11.6 6.9 8.4 8.0 10.3 6.9 5.2 6.8 5.8 5.2 8.6 8.8 9.6 8.7 7.7 6.6 4.6 7.9 7.4 6.9 12.4 11.2 8.0 5.8 7.9 6.8 5.7 9.9 9.1 4.2 8.8 9.5 9.8 3.8 6.3 4.5 8.4 3.6 8.0 3.9 10.6 4.4 3.3 6.3 6.7 10.5 7.0 4.1 7.6 12.1 6.4 5.6 4.0 3.1 4.6 3.1 3.8 6.5 12.8 8.9 9.8 4.3 4.6 9.1 9.9 8.3 3.8 12.5 10.2 8.2 9.2 6.3 9.1 9.3 11.6 5.6 7.0 2.6 11.4 9.6 7.1 12.4 4.6 7.7 6.8 7.6 7.5 6.8 10.0 11.8 3.0 7.8 8.0 8.2 11.6 10.5 6.6 5.5 7.6 9.8 16.6 24.6 6.9 4.6 13.1 4.2 1.2 6.1 7.5 4.8 1.5 4.2 9.8 9.8 9.5 5.2 0.7 1.8 0.7 0.7 1.2 0.9 0.9 1.2 0.7 1.1 1.0 1.3 0.7 0.6 0.7 1.1 1.0 0.4 8.1 7.8 19.4 11.6 8.8 9.6 7.9 7.4 7.9 6.3 8.0 10.5 51.0 41.7 38.6 69.5 60.8 105.3 83.5 30.8 70.6 147.8 65.1 47.9 34.8 42.9 35.4 46.0 143.9 75.7 62.8 59.7 70.5 50.0 59.4 49.4 41.5 60.3 45.6 32.4 115.1 41.2 41.9 34.2 43.8 67.9 31.1 46.8 42.8 36.0 25.6 129.5 100.9 52.3 26.4 25.8 76.7 7.2 41.0 46.5 55.2 35.6 34.8 73.9 70.0 54.3 57.8 47.7 57.9 33.4 34.5 89.1 75.4 47.1 26.5 180.4 46.0 56.5 40.2 30.2 31.1 56.9 116.8 65.5 68.9 69.9 63.3 72.7 TUFM "EF-TuMT, EFTu" ENSG00000178952 "Tu translation elongation factor, mitochondrial" P49411 16 28842411-28846348 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Elongation factor" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018991, HPA024087, CAB075730, CAB075731, CAB075732" Enhanced Enhanced Mitochondria NA NA 610000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB075730: AB_2665736, CAB075731: AB_2665737, CAB075732: AB_2665738, HPA018991: AB_1858458, HPA024087: AB_1858459" "unprognostic (1.40e-1)" "unprognostic (7.56e-2)" "unprognostic (1.29e-1)" "unprognostic (1.73e-2)" "unprognostic (2.36e-1)" "unprognostic (2.55e-2)" "unprognostic (3.39e-1)" "unprognostic (1.23e-3)" "unprognostic (8.05e-2)" "unprognostic (8.47e-2)" "unprognostic (1.80e-1)" "unprognostic (1.33e-1)" "prognostic favorable (2.69e-6)" "unprognostic (5.26e-2)" "unprognostic (1.09e-1)" "unprognostic (6.22e-2)" "unprognostic (7.36e-2)" 69.7 114.6 69.6 67.1 74.2 75.1 65.8 78.9 78.1 59.4 93.3 101.5 104.4 64.9 34.7 105.2 73.6 46.6 177.8 68.1 75.3 107.3 145.1 58.3 69.2 73.1 77.4 61.4 114.2 117.1 55.4 47.6 74.1 57.7 86.1 35.8 88.9 59.7 224.4 76.0 83.9 53.6 72.9 66.2 106.1 73.3 77.0 59.9 62.7 221.5 79.3 67.1 62.9 74.3 176.2 323.1 102.4 216.2 144.9 131.4 208.7 125.8 144.4 194.9 183.0 351.3 189.4 390.5 228.5 126.4 112.4 337.6 244.2 242.9 116.2 155.4 370.8 151.7 254.8 433.6 171.7 273.8 134.8 169.9 188.1 211.9 208.7 126.8 235.2 213.0 339.0 150.3 144.4 355.0 262.3 266.3 231.8 213.9 196.9 361.8 187.3 569.6 169.3 168.4 178.8 219.6 110.0 388.5 180.2 84.6 231.5 217.6 150.1 115.9 136.4 146.7 196.6 229.8 253.6 172.2 148.6 336.8 157.1 94.6 155.8 72.3 103.1 153.6 115.3 100.6 97.2 108.7 199.3 98.8 91.7 95.3 32.4 97.2 119.2 123.1 140.1 185.6 69.6 74.2 78.9 78.1 68.1 75.3 73.1 77.4 74.1 72.9 77.0 74.3 108.2 70.5 76.7 29.4 144.6 168.1 262.5 322.0 158.2 102.4 165.1 139.2 134.4 190.1 182.6 176.6 87.6 333.1 113.2 260.0 334.6 230.2 381.8 116.1 92.5 111.3 148.5 148.1 17.5 289.8 299.2 111.2 153.4 79.6 105.9 170.6 108.5 247.1 253.8 74.0 19.9 230.5 217.7 167.5 146.4 669.0 109.3 128.6 138.7 14.0 167.5 140.6 88.6 28.6 30.3 199.7 215.3 111.7 264.9 245.3 330.7 451.9 237.3 116.3 85.5 105.5 129.1 205.7 177.4 230.1 156.0 287.0 120.2 288.2 418.7 277.6 TXN2 MT-TRX ENSG00000100348 "Thioredoxin 2" Q99757 22 36467046-36481640 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Transport" "Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000994, CAB008681" Approved Enhanced Mitochondria No No 84000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB008681: AB_1623682, HPA000994: AB_1080267" "unprognostic (5.11e-2)" "unprognostic (4.40e-3)" "unprognostic (4.40e-3)" "unprognostic (1.07e-2)" "unprognostic (5.85e-2)" "unprognostic (4.28e-2)" "unprognostic (4.02e-2)" "unprognostic (5.05e-2)" "unprognostic (2.15e-1)" "unprognostic (1.78e-1)" "unprognostic (3.17e-2)" "prognostic favorable (2.04e-4)" "prognostic favorable (1.17e-6)" "unprognostic (1.49e-2)" "unprognostic (2.78e-1)" "unprognostic (1.06e-1)" "unprognostic (2.05e-1)" 60.3 182.3 89.8 45.5 92.4 64.7 58.0 94.6 98.2 57.4 92.4 65.3 84.0 50.0 51.7 79.8 64.1 49.4 122.3 87.9 90.7 91.5 149.5 44.7 59.2 92.9 91.3 75.8 59.2 99.1 43.4 47.3 91.9 59.3 63.6 43.0 59.5 52.5 159.4 60.5 64.3 48.3 91.2 65.7 76.1 48.8 97.0 50.9 67.7 180.1 59.9 59.0 54.0 91.7 52.8 80.4 75.4 126.8 115.2 125.0 81.3 70.8 108.1 114.8 128.7 87.9 52.1 133.3 64.2 116.8 54.5 76.1 151.7 127.4 66.1 93.6 131.8 147.7 91.7 125.4 94.6 189.6 125.8 162.3 98.9 101.9 79.3 99.5 118.2 78.4 157.7 104.1 106.1 80.3 87.5 128.2 60.0 170.3 95.3 75.3 79.5 92.6 116.4 84.8 99.9 98.3 70.2 148.1 125.3 61.3 103.6 165.9 83.7 120.5 95.0 69.8 65.9 81.4 64.2 128.6 111.0 109.5 74.1 30.2 173.5 32.3 102.5 194.3 108.9 140.4 101.2 109.0 223.4 133.8 116.4 108.6 59.3 145.4 170.1 167.1 110.9 224.3 89.8 92.4 94.6 98.2 87.9 90.7 92.9 91.3 91.9 91.2 97.0 91.7 68.9 60.9 53.0 12.1 66.4 83.5 87.7 154.0 108.1 105.6 124.3 137.7 105.4 88.6 82.5 69.9 39.6 213.2 62.8 128.5 303.3 93.0 19.6 45.7 70.6 73.7 89.5 114.0 8.3 106.2 275.8 74.0 75.4 57.2 69.1 148.0 81.0 122.7 173.4 116.1 10.3 132.4 95.6 100.5 80.7 36.8 56.5 80.7 78.2 8.4 91.9 168.9 77.2 9.0 13.5 82.5 104.3 50.8 79.5 52.7 252.2 213.7 49.0 59.4 19.7 61.1 67.1 49.1 42.4 124.5 89.8 207.1 62.4 287.0 179.6 87.1 UQCRC2 "QCR2, UQCR2" ENSG00000140740 "Ubiquinol-cytochrome c reductase core protein 2" P22695 16 21953288-21983660 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 722.2;tongue: 933.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 556.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007998, HPA019146" Enhanced Enhanced Mitochondria NA NA 180000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA007998: AB_1858648, HPA019146: AB_1858649" "unprognostic (1.33e-1)" "unprognostic (1.32e-1)" "unprognostic (1.49e-3)" "unprognostic (3.35e-1)" "unprognostic (1.26e-2)" "unprognostic (6.91e-2)" "unprognostic (2.71e-2)" "unprognostic (1.32e-1)" "unprognostic (1.72e-1)" "unprognostic (8.87e-2)" "unprognostic (1.67e-2)" "unprognostic (2.43e-2)" "prognostic favorable (6.58e-9)" "unprognostic (2.33e-1)" "unprognostic (9.78e-3)" "unprognostic (4.67e-3)" "unprognostic (7.36e-2)" 158.8 117.7 69.0 103.1 71.2 127.7 108.4 75.5 90.0 90.8 113.9 259.8 292.5 98.2 72.7 157.4 109.7 99.5 559.4 72.4 73.7 240.0 245.1 75.4 120.0 74.1 69.5 114.5 89.7 257.2 39.8 96.5 72.7 95.6 262.8 142.3 133.8 104.3 722.2 85.4 233.6 121.2 65.8 80.9 153.2 55.8 76.5 131.3 107.9 933.2 149.3 153.6 59.8 73.3 173.9 193.1 116.5 66.4 154.3 186.8 169.1 163.8 160.6 177.5 174.5 347.9 177.7 338.9 144.3 170.4 129.8 324.6 222.3 212.7 193.7 151.4 178.4 185.9 166.1 494.3 164.6 249.1 501.2 232.3 229.4 130.3 186.2 169.4 248.1 224.1 217.9 159.1 177.2 230.6 288.6 175.0 124.6 261.1 148.8 310.9 263.6 390.0 285.8 214.6 154.4 114.9 237.2 318.6 190.3 151.6 354.4 264.1 179.3 103.3 98.1 104.0 148.0 126.3 87.2 302.7 188.7 239.8 126.4 80.1 128.7 71.4 80.0 147.8 103.3 96.0 98.3 89.3 153.9 77.9 106.8 97.6 45.9 101.8 148.1 67.6 134.8 157.3 69.0 71.2 75.5 90.0 72.4 73.7 74.1 69.5 72.7 65.8 76.5 73.3 105.5 64.1 52.5 81.9 81.1 90.6 190.8 444.0 74.6 109.1 91.7 79.6 556.2 84.4 194.9 71.7 87.6 238.3 82.6 233.4 455.9 124.5 88.0 72.0 55.7 91.3 113.8 92.4 65.0 109.6 157.6 89.0 144.3 65.8 92.6 99.6 84.3 122.3 195.5 69.0 74.0 224.4 238.0 145.1 100.6 89.9 68.3 104.6 131.6 27.2 162.1 108.0 91.6 60.3 50.7 97.2 214.0 97.0 72.9 114.4 378.0 306.9 110.2 152.6 78.9 94.1 109.5 68.9 56.7 132.0 88.4 278.3 91.3 170.2 358.7 204.3 UQCRQ "QCR8, QP-C, UQCR7" ENSG00000164405 "Ubiquinol-cytochrome c reductase complex III subunit VII" O14949 5 132866630-132868847 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1301.6" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 3312.4;Hepatocytes: 5039.2;Proximal tubular cells: 3336.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046693, HPA053323" Approved Enhanced Mitochondria NA NA 18000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA046693: AB_10968453, HPA053323: AB_2682112" "unprognostic (3.22e-1)" "unprognostic (1.06e-1)" "unprognostic (4.92e-2)" "prognostic favorable (4.23e-4)" "unprognostic (1.09e-1)" "unprognostic (9.03e-2)" "unprognostic (1.02e-1)" "unprognostic (3.45e-2)" "unprognostic (1.37e-1)" "unprognostic (3.72e-2)" "unprognostic (7.31e-2)" "unprognostic (3.49e-1)" "unprognostic (1.81e-3)" "unprognostic (1.06e-1)" "unprognostic (1.84e-1)" "unprognostic (2.33e-1)" "unprognostic (3.37e-2)" 226.5 378.7 277.6 91.8 283.7 132.6 189.2 309.6 391.9 151.7 293.2 313.0 220.8 147.9 211.2 332.4 138.6 78.3 1301.6 283.6 315.5 460.7 1036.6 149.0 69.1 291.2 285.6 120.0 269.4 318.5 222.8 89.0 294.9 272.9 232.2 187.4 253.8 122.2 1024.7 182.3 244.5 98.5 286.6 151.8 372.3 128.9 294.7 130.3 167.3 873.5 92.3 219.9 193.3 302.3 300.9 391.1 246.7 599.9 364.2 292.2 209.3 216.3 310.6 341.7 424.9 556.4 353.8 126.5 433.4 291.5 424.5 302.7 229.5 536.6 300.7 222.9 466.0 169.4 606.3 459.9 312.7 188.8 276.2 314.0 366.5 247.4 341.6 229.6 274.1 258.3 219.2 398.6 369.7 547.5 450.5 442.1 175.3 568.1 367.0 288.4 271.7 541.7 460.9 573.4 410.7 335.8 269.1 302.7 493.9 170.4 451.9 422.5 168.3 316.0 392.1 257.2 438.7 423.1 616.3 236.6 417.9 350.0 320.6 474.1 528.3 355.5 245.6 431.0 251.8 317.2 280.3 280.2 472.0 260.6 273.5 263.6 258.8 322.9 410.0 516.7 326.1 658.2 277.6 283.7 309.6 391.9 283.6 315.5 291.2 285.6 294.9 286.6 294.7 302.3 252.0 250.0 349.3 17.6 258.1 348.3 334.0 1046.6 235.6 97.8 575.5 657.7 3312.4 993.7 556.9 787.2 120.9 720.4 200.6 1678.3 1813.7 685.6 470.0 424.1 308.5 288.4 549.3 319.4 13.9 947.7 484.1 330.2 438.3 467.5 294.5 277.0 333.8 5039.2 771.4 72.3 17.0 1047.6 807.7 421.1 448.6 1116.6 282.4 301.6 715.1 11.2 394.7 459.2 260.6 13.6 23.5 705.7 1460.8 288.9 416.2 537.1 2476.1 3336.0 512.5 271.5 184.1 217.8 388.7 308.1 174.7 570.1 514.0 562.7 205.0 235.9 1205.6 500.2