Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" A4GALT "A14GALT, Gb3S, P(k), P1" ENSG00000128274 "Alpha 1,4-galactosyltransferase (P blood group)" Q9NPC4 22 42692121-42721298 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 70.7;Proximal tubular cells: 91.0;Urothelial cells: 74.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 38.7;ASC TERT1: 31.3;RPTEC TERT1: 27.1;TIME: 29.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001141 Uncertain Mitochondria NA NA 22000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Mitochondria "HPA001141: AB_1078139" "unprognostic (2.59e-2)" "prognostic favorable (2.48e-4)" "unprognostic (2.24e-2)" "unprognostic (4.54e-3)" "unprognostic (7.41e-2)" "unprognostic (1.53e-1)" "unprognostic (8.20e-2)" "unprognostic (2.10e-1)" "unprognostic (2.30e-1)" "unprognostic (1.28e-1)" "unprognostic (4.82e-3)" "unprognostic (4.16e-2)" "unprognostic (1.80e-2)" "unprognostic (1.96e-1)" "unprognostic (8.72e-2)" "unprognostic (3.46e-2)" "unprognostic (2.74e-1)" 41.5 14.3 6.2 6.1 6.0 4.1 31.3 5.0 8.0 29.6 8.0 30.9 4.5 28.1 3.3 30.6 29.2 4.4 77.0 6.2 5.3 51.3 4.3 26.0 6.8 7.8 5.8 7.8 6.2 1.2 16.7 9.1 5.6 35.1 1.7 0.3 36.1 21.3 19.4 20.8 18.2 6.9 6.0 16.2 26.6 6.2 7.1 1.6 25.1 6.3 5.1 38.1 38.2 6.0 1.2 13.6 0.0 0.0 38.7 31.3 20.1 5.5 5.8 1.2 2.1 4.3 2.2 13.6 9.4 9.7 6.7 1.3 12.9 6.5 0.2 0.0 2.7 0.3 21.1 0.5 11.5 0.0 0.9 18.6 1.8 5.5 0.9 1.8 4.7 0.0 0.1 0.0 5.1 19.0 0.0 0.0 1.6 0.9 3.3 0.0 3.0 1.4 27.1 23.4 0.2 0.0 16.9 0.3 0.0 2.4 10.6 1.6 29.3 0.0 2.6 24.3 7.3 2.8 13.1 0.1 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.9 0.0 0.0 6.2 6.0 5.0 8.0 6.2 5.3 7.8 5.8 5.6 6.0 7.1 6.0 47.1 0.0 0.5 0.3 1.6 9.2 28.9 70.7 0.0 0.1 4.2 1.5 15.8 1.5 41.2 18.4 0.0 48.7 0.4 0.2 13.7 23.1 0.7 11.1 10.3 43.7 0.0 10.7 0.1 1.1 35.3 43.8 2.6 17.4 1.3 0.2 30.7 0.2 5.3 0.0 0.1 0.0 14.2 1.0 11.8 4.4 46.3 4.0 7.2 7.5 30.0 0.8 0.0 0.5 0.0 3.6 0.0 30.1 0.1 40.1 0.0 91.0 12.1 0.6 39.5 7.6 29.3 0.6 0.6 1.2 8.8 9.4 1.5 19.9 0.1 74.7 AARS2 "AARSL, bA444E17.1, KIAA1270" ENSG00000124608 "Alanyl-tRNA synthetase 2, mitochondrial" Q5JTZ9 6 44298731-44313347 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, RNA-binding, tRNA-binding" "Cancer-related genes, Cardiomyopathy, Disease variant, Neurodegeneration, Premature ovarian failure, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035636, HPA061396" Approved Enhanced Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 23: Spermatids - Flagellum & Golgi organization" Mitochondria "HPA035636: AB_10670837, HPA061396: AB_2684502" "unprognostic (1.56e-1)" "unprognostic (3.24e-2)" "unprognostic (2.58e-2)" "unprognostic (2.04e-3)" "unprognostic (2.83e-1)" "unprognostic (1.69e-1)" "unprognostic (8.83e-3)" "unprognostic (5.12e-2)" "unprognostic (3.64e-2)" "unprognostic (1.38e-1)" "unprognostic (2.19e-2)" "unprognostic (1.37e-2)" "unprognostic (1.74e-1)" "unprognostic (1.84e-1)" "unprognostic (1.48e-1)" "unprognostic (1.08e-1)" "unprognostic (2.02e-1)" 4.7 5.2 6.5 5.6 6.2 5.4 4.9 9.4 6.7 7.6 6.7 5.8 6.5 6.1 3.2 9.2 6.4 4.6 6.0 6.8 5.1 5.7 6.9 4.3 6.0 6.1 5.8 8.3 6.5 5.9 6.3 4.1 6.4 7.0 4.1 5.4 6.2 4.3 4.8 7.2 7.9 4.1 5.4 7.2 5.4 3.7 6.0 6.2 6.2 3.3 5.3 5.6 7.4 6.7 14.6 9.9 13.9 23.8 8.1 7.2 18.3 10.9 5.7 11.2 10.6 11.4 7.1 16.3 16.2 4.8 12.2 10.0 14.7 16.0 4.7 10.9 23.7 18.9 10.6 14.5 4.8 17.9 16.0 5.9 9.8 9.0 10.2 7.3 9.5 21.8 21.0 15.4 6.2 16.0 14.2 15.9 9.9 40.3 9.8 16.4 8.7 10.4 6.7 12.7 32.0 11.4 9.4 10.9 15.5 9.7 9.9 21.6 8.4 12.1 13.5 7.6 13.9 8.8 8.7 16.5 6.8 15.9 22.1 2.2 1.1 0.1 1.3 1.3 2.1 1.5 1.9 1.7 1.0 2.9 1.8 1.7 0.2 1.9 1.4 1.3 1.2 1.3 6.5 6.2 9.4 6.7 6.8 5.1 6.1 5.8 6.4 5.4 6.0 6.7 2.6 6.4 3.3 5.2 3.7 0.6 2.1 1.9 4.0 6.6 2.8 2.7 3.5 5.7 2.8 0.0 12.5 5.0 4.9 3.0 0.0 2.3 10.1 3.5 5.4 3.0 0.0 8.2 5.5 0.4 5.0 3.4 5.1 6.2 0.0 5.9 3.9 2.5 3.3 0.0 9.0 2.2 2.0 2.8 1.8 1.0 4.7 2.5 0.0 1.9 3.9 2.0 4.1 3.0 3.6 1.4 0.7 4.5 6.9 1.6 6.3 1.0 3.0 7.1 0.0 4.7 2.8 4.3 6.1 4.4 0.4 5.3 4.1 4.5 3.7 1.6 AATK "AATYK, AATYK1, KIAA0641, LMR1, LMTK1, PPP1R77" ENSG00000181409 "Apoptosis associated tyrosine kinase" Q6ZMQ8 17 81110487-81166221 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 184.7" "Cell type enriched" "Detected in many" 5 "Oligodendrocytes: 243.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "neutrophil: 2.0" "Lineage enriched" "Detected in single" 11 "granulocytes: 2.0" "Group enriched" "Detected in some" 6 "CACO-2: 60.1;SH-SY5Y: 17.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009073 Enhanced Uncertain Mitochondria NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 70: Brain - Nervous system development" "Cluster 39: CACO-2 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA009073: AB_1078076" "unprognostic (3.47e-3)" "unprognostic (3.01e-2)" "unprognostic (1.12e-1)" "unprognostic (1.95e-4)" "unprognostic (1.96e-1)" "unprognostic (1.94e-1)" "unprognostic (7.29e-2)" "unprognostic (9.85e-2)" "unprognostic (6.09e-2)" "unprognostic (4.27e-2)" "unprognostic (2.88e-3)" "unprognostic (2.48e-1)" "unprognostic (4.28e-6)" "unprognostic (1.58e-3)" "unprognostic (1.21e-1)" "unprognostic (1.39e-1)" "unprognostic (4.57e-2)" 3.3 4.2 35.4 3.1 79.2 3.7 2.3 43.4 82.0 2.8 0.0 7.7 30.9 0.9 0.5 1.8 2.8 2.7 3.9 30.6 30.8 1.0 0.9 9.5 0.9 99.2 67.9 0.9 20.6 3.0 17.3 2.0 63.4 5.2 0.5 2.1 5.9 3.3 0.6 4.5 23.7 0.8 38.8 9.7 5.8 0.7 78.4 0.1 2.9 1.0 0.2 2.8 4.2 184.7 0.3 0.5 0.7 4.9 0.0 0.0 0.7 0.1 0.0 0.0 0.0 60.1 0.2 0.0 0.3 0.0 0.0 1.2 0.6 0.0 0.0 0.0 2.0 2.2 3.2 2.8 0.1 0.0 3.9 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 1.4 0.0 6.6 0.0 0.2 0.7 0.6 0.3 2.1 4.1 0.6 0.0 0.2 4.5 17.1 0.2 0.4 2.3 0.2 1.1 2.2 2.1 0.4 0.5 0.4 0.0 0.1 0.0 0.0 0.2 1.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.0 35.4 79.2 43.4 82.0 30.6 30.8 99.2 67.9 63.4 38.8 78.4 184.7 6.3 32.1 20.3 17.0 0.3 0.3 1.0 1.9 0.6 43.0 1.3 5.1 2.2 2.8 0.1 0.0 4.2 0.1 0.5 6.8 0.0 0.6 0.0 0.4 0.2 1.8 1.8 0.0 34.6 1.8 0.1 0.5 7.1 0.6 6.3 2.0 1.1 0.1 2.1 21.9 36.0 4.6 0.0 2.8 0.4 0.0 1.5 8.2 5.4 2.8 1.5 9.6 4.1 21.1 243.2 1.1 4.2 2.6 0.1 0.9 34.1 0.9 0.0 4.4 0.0 4.3 0.8 0.4 0.5 0.0 0.3 2.3 1.4 0.4 7.0 0.2 ABAT "GABA-T, GABAT" ENSG00000183044 "4-aminobutyrate aminotransferase" P80404 16 8674596-8784575 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Neurotransmitter degradation" "Aminotransferase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 137.9;kidney: 133.3;liver: 345.6;pancreas: 138.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 268.2;Inhibitory neurons: 95.0;Oligodendrocyte precursor cells: 76.9;Proximal tubular cells: 94.9" "Cancer enhanced" "Detected in all" "glioma: 27.3;liver cancer: 26.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 127.5;MCF7: 81.9;RH-30: 67.4;T-47d: 42.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041528, HPA041690" Enhanced Supported Supported Mitochondria No No 2100000 "Cluster 14: Monocytes - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA041528: AB_10795690, HPA041690: AB_10794674" "unprognostic (1.77e-2)" "unprognostic (3.27e-1)" "unprognostic (1.00e-1)" "unprognostic (2.71e-1)" "unprognostic (2.90e-1)" "unprognostic (2.05e-1)" "prognostic favorable (5.36e-5)" "prognostic favorable (5.93e-4)" "unprognostic (1.71e-1)" "unprognostic (1.30e-1)" "unprognostic (1.56e-2)" "unprognostic (1.04e-1)" "prognostic favorable (5.44e-8)" "unprognostic (2.10e-1)" "unprognostic (2.48e-2)" "unprognostic (3.80e-1)" "unprognostic (1.50e-2)" 3.3 27.7 94.6 4.7 105.4 2.2 5.1 85.2 103.4 3.8 70.7 7.6 43.6 3.8 9.6 7.7 6.2 4.4 14.1 90.2 120.7 133.3 345.6 4.5 5.0 90.8 107.4 10.5 138.3 8.2 55.8 3.4 137.6 21.7 7.8 29.6 6.5 3.5 1.6 2.7 20.1 2.7 88.1 4.1 7.4 13.4 137.9 4.2 29.3 1.4 5.9 9.9 4.1 70.9 0.7 0.2 32.1 18.7 5.0 1.7 2.0 4.2 2.2 1.8 0.7 12.7 0.9 4.0 1.4 2.3 1.2 8.3 2.1 7.7 2.4 2.3 2.1 5.5 0.1 127.5 8.1 1.3 8.3 6.5 3.4 3.2 1.4 0.9 0.6 10.7 1.1 2.6 0.6 81.9 2.1 0.6 2.8 23.2 0.3 9.7 67.4 1.8 1.2 20.9 5.1 15.7 1.9 1.0 0.2 6.2 42.6 3.4 0.6 0.8 5.7 2.7 0.1 3.0 0.3 0.8 0.8 5.7 4.2 0.7 1.9 2.7 1.5 2.2 0.7 0.6 1.0 1.1 1.2 1.2 0.7 1.1 6.1 1.2 4.2 0.2 1.1 1.2 94.6 105.4 85.2 103.4 90.2 120.7 90.8 107.4 137.6 88.1 137.9 70.9 1.7 0.0 6.9 39.5 6.1 1.5 4.0 3.3 2.2 27.3 9.1 5.0 10.8 20.0 5.8 1.8 4.2 1.4 5.3 8.9 23.5 1.6 13.0 12.9 6.2 2.4 15.6 13.9 41.8 6.2 1.5 3.2 5.6 12.9 1.3 59.5 7.1 268.2 5.2 35.3 95.0 3.9 2.0 15.7 7.4 8.7 3.7 8.2 1.8 19.7 6.5 48.6 9.2 76.9 17.7 6.8 6.1 4.5 1.0 7.4 15.7 94.9 3.6 5.8 0.0 4.3 3.8 3.7 0.9 9.5 0.6 1.4 6.3 2.3 6.9 5.0 ABCB7 "ABC7, ASAT, Atm1p, EST140535" ENSG00000131269 "ATP binding cassette subfamily B member 7" O75027 X 75051048-75156732 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034982 Approved Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA034982: AB_10601010" "unprognostic (1.05e-2)" "unprognostic (1.45e-1)" "unprognostic (1.49e-2)" "unprognostic (1.83e-3)" "unprognostic (4.44e-3)" "unprognostic (1.33e-2)" "unprognostic (6.31e-2)" "unprognostic (4.39e-2)" "unprognostic (1.47e-1)" "unprognostic (2.17e-1)" "unprognostic (4.14e-2)" "unprognostic (2.55e-2)" "prognostic favorable (5.31e-6)" "unprognostic (1.95e-1)" "unprognostic (1.27e-1)" "unprognostic (1.45e-1)" "unprognostic (1.08e-1)" 12.6 13.5 5.0 7.7 5.9 11.1 11.8 8.2 7.6 11.4 9.8 13.8 16.0 10.9 5.0 11.6 11.2 7.4 22.0 5.5 6.1 10.1 14.8 9.8 12.0 6.4 6.0 12.3 9.6 11.0 8.6 7.5 6.2 8.5 9.6 9.8 10.0 6.9 31.4 12.9 11.8 8.8 6.1 10.9 12.3 4.1 5.4 14.0 9.5 22.2 11.1 10.5 10.9 6.8 17.0 16.2 12.2 20.9 14.1 25.5 7.0 8.9 14.6 12.3 22.4 18.5 24.5 25.8 22.8 9.2 21.2 18.8 25.6 18.5 12.0 26.0 33.2 16.8 29.2 17.3 8.2 24.7 13.7 15.9 16.3 12.8 16.7 21.3 23.1 26.2 18.9 31.1 9.8 10.5 24.4 26.1 26.8 26.3 30.5 21.4 26.9 30.5 12.7 13.2 17.7 14.1 27.4 23.5 17.8 20.0 10.2 22.9 10.3 11.3 22.9 23.2 12.4 10.1 27.5 21.2 10.1 35.8 9.4 9.6 26.9 10.0 15.7 25.6 16.6 24.7 16.7 16.7 29.0 28.2 28.7 21.1 2.4 17.5 20.4 18.2 27.2 19.2 5.0 5.9 8.2 7.6 5.5 6.1 6.4 6.0 6.2 6.1 5.4 6.8 12.0 9.6 10.4 48.0 26.6 15.8 14.5 16.0 19.9 10.9 10.9 9.9 46.8 14.3 14.2 11.0 6.2 23.0 19.0 8.2 11.7 17.5 0.4 8.4 12.8 11.9 13.8 26.9 37.9 13.5 11.6 13.9 9.7 10.1 22.2 20.6 9.3 11.8 20.1 25.2 39.0 10.5 8.2 26.1 16.7 0.8 14.6 19.2 10.6 45.0 22.9 12.4 6.2 43.7 46.6 11.6 7.9 13.2 14.3 10.6 15.9 19.9 10.7 7.9 32.9 19.6 13.8 5.5 10.9 16.1 16.1 22.3 14.5 19.2 17.9 11.9 ABHD10 FLJ11342 ENSG00000144827 "Abhydrolase domain containing 10, depalmitoylase" Q9NUJ1 3 111979010-111993368 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036991, HPA036992, HPA066081" Supported Approved Mitochondria "Intracellular and membrane" No No 71000 "Cluster 46: Basophils - DNA binding" "Cluster 7: Kidney - Transmembrane transport" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA036991: AB_2675420, HPA036992: AB_10672345, HPA066081: AB_2685610" "unprognostic (1.65e-1)" "prognostic favorable (7.57e-4)" "unprognostic (1.61e-1)" "unprognostic (1.63e-1)" "unprognostic (1.05e-1)" "unprognostic (1.30e-2)" "unprognostic (8.95e-2)" "unprognostic (1.14e-1)" "unprognostic (8.50e-2)" "unprognostic (1.69e-2)" "unprognostic (1.70e-1)" "unprognostic (3.91e-2)" "prognostic favorable (4.72e-9)" "unprognostic (1.59e-2)" "unprognostic (1.72e-1)" "unprognostic (4.18e-3)" "unprognostic (2.76e-2)" 11.0 21.9 23.0 10.6 25.3 10.9 15.0 24.5 29.3 11.3 22.9 14.1 11.7 11.1 50.8 8.2 14.9 10.1 25.0 23.9 24.6 49.4 34.4 10.1 17.9 23.5 23.2 19.8 13.7 16.7 27.9 10.8 23.7 20.4 14.7 27.0 25.5 13.7 14.1 10.0 10.3 10.0 24.4 14.6 14.9 16.4 26.3 21.8 31.1 19.6 16.2 9.5 8.3 25.3 40.2 34.1 36.4 12.0 20.5 27.5 19.8 41.4 21.5 33.0 31.7 35.3 22.4 36.0 22.6 17.2 22.7 21.6 16.3 23.0 44.9 12.1 20.6 29.7 15.4 30.7 16.3 60.3 30.4 16.9 16.7 17.0 42.4 22.7 35.9 42.1 13.9 14.9 36.7 13.7 56.9 27.9 23.7 43.8 53.2 50.9 23.4 16.7 34.6 17.1 24.6 17.9 33.2 23.7 39.8 14.3 26.8 21.8 20.6 19.7 25.3 14.4 21.7 23.6 9.0 61.4 20.1 32.4 21.5 29.4 16.5 25.2 9.8 21.6 16.8 26.2 12.2 11.3 28.1 21.6 15.4 13.9 2.5 11.4 17.3 17.8 13.2 16.1 23.0 25.3 24.5 29.3 23.9 24.6 23.5 23.2 23.7 24.4 26.3 25.3 9.1 0.0 7.2 11.1 19.7 7.0 10.2 12.1 14.2 21.8 12.7 10.9 26.1 7.2 12.4 11.0 8.4 19.2 16.1 7.0 35.2 5.2 1.0 11.1 10.3 8.8 12.1 24.2 16.0 7.8 14.9 12.3 12.8 6.8 9.5 9.5 10.0 26.2 14.1 42.1 16.2 13.4 6.1 19.5 7.0 3.0 10.5 11.0 10.6 15.0 10.7 20.4 12.3 14.6 15.6 5.4 4.0 7.5 25.0 5.1 7.0 42.5 19.5 16.2 0.0 7.9 8.9 29.7 37.0 13.6 8.2 5.5 14.6 19.2 12.1 4.5 ABHD11 "PP1226, WBSCR21" ENSG00000106077 "Abhydrolase domain containing 11" Q8NFV4 7 73736094-73738867 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hydrolase "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 156.9;Urothelial cells: 241.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 92.6;SK-BR-3: 113.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024042, HPA049641" Approved Supported Mitochondria NA NA 31000 "Cluster 7: Monocytes - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA024042: AB_1844445, HPA049641: AB_2680838" "unprognostic (4.74e-2)" "unprognostic (8.62e-3)" "unprognostic (1.42e-1)" "unprognostic (2.51e-2)" "unprognostic (3.56e-3)" "unprognostic (1.73e-1)" "unprognostic (1.83e-1)" "unprognostic (1.81e-3)" "unprognostic (1.91e-2)" "unprognostic (9.32e-2)" "unprognostic (7.79e-2)" "unprognostic (1.74e-1)" "prognostic favorable (3.66e-7)" "unprognostic (3.61e-3)" "unprognostic (4.44e-2)" "unprognostic (1.02e-1)" "unprognostic (7.29e-2)" 7.5 13.5 9.3 5.6 9.8 4.5 12.2 10.6 11.3 9.3 16.4 31.3 15.9 7.2 5.8 13.6 13.8 8.6 21.6 9.1 9.9 29.4 9.5 9.5 4.0 11.4 11.1 3.9 25.7 12.9 16.4 7.6 11.0 23.2 17.4 3.0 21.3 8.2 11.3 13.3 19.8 3.5 10.4 8.1 9.0 7.2 12.3 3.3 28.1 10.3 5.4 8.5 6.9 10.4 46.9 10.7 7.1 16.4 3.7 5.0 39.7 21.1 8.9 12.7 14.9 13.1 51.4 22.2 6.2 9.0 17.3 20.2 3.2 12.1 8.8 8.2 15.4 10.8 6.7 8.3 6.5 11.8 11.4 4.6 5.0 16.4 7.6 4.6 9.2 7.4 15.1 11.8 12.0 92.6 9.2 14.9 8.3 29.5 39.1 5.0 11.4 41.0 29.7 21.8 18.3 7.6 17.1 113.0 7.1 5.1 36.8 7.8 9.1 10.8 10.2 46.5 22.2 7.3 4.2 14.8 17.3 11.2 20.3 10.2 19.1 19.3 8.2 32.7 6.8 10.1 9.1 8.7 19.4 12.7 8.4 5.9 15.2 14.9 33.5 9.2 6.3 11.9 9.3 9.8 10.6 11.3 9.1 9.9 11.4 11.1 11.0 10.4 12.3 10.4 7.9 44.8 15.7 3.3 10.6 5.5 60.3 39.8 10.2 16.6 43.1 21.7 16.9 54.3 60.7 57.0 4.2 86.3 8.7 156.9 72.4 52.1 1.2 98.9 17.3 9.7 62.6 9.4 5.8 40.8 120.1 9.9 35.7 98.1 15.2 6.3 4.6 8.7 28.0 5.0 4.0 106.8 95.6 11.3 10.5 2.3 9.0 13.7 14.2 4.7 10.4 26.6 14.4 3.0 3.7 38.2 151.7 3.4 10.5 53.1 128.2 55.3 127.6 15.2 0.0 10.3 14.4 6.8 7.1 23.3 6.3 127.7 9.6 22.1 128.9 241.3 AC008982.1 ENSG00000268083 "Novel protein" 19 38817471-38840178 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "cerebral cortex: 2.1" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 4 "NB-4: 26.4" "HPA002907, HPA051748" Uncertain Uncertain Mitochondria NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 11: Alveolar cells - Smell perception" Mitochondria "HPA002907: AB_1847964, HPA051748: AB_2681588" "unprognostic (1.36e-2)" 0.6 0.2 0.4 0.1 0.4 1.0 0.2 0.4 2.1 0.2 0.4 0.7 0.5 0.3 0.0 0.2 0.1 0.0 0.4 0.4 0.4 0.3 0.2 0.5 0.3 0.4 0.4 0.2 0.3 0.0 0.1 0.2 0.4 0.2 0.0 0.1 0.2 0.1 1.4 0.3 0.3 0.0 0.4 0.2 0.2 0.3 0.4 0.0 0.2 0.4 0.0 0.1 0.2 0.4 1.5 0.0 0.2 0.3 0.1 0.1 1.8 0.5 0.0 0.6 0.1 0.8 0.1 0.2 1.2 0.1 0.1 0.8 0.0 0.0 0.2 1.5 0.5 1.0 0.0 0.0 0.1 0.5 1.1 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.6 0.5 0.0 0.9 1.3 26.4 1.9 0.0 0.0 1.6 0.8 0.7 0.3 0.3 0.7 2.9 0.0 0.0 6.0 0.0 0.5 3.0 0.0 0.1 2.7 1.6 2.1 1.3 1.0 2.2 0.1 0.8 0.1 0.5 0.7 0.7 0.6 0.5 1.0 0.4 0.7 0.7 0.6 0.5 0.6 0.8 0.0 0.8 0.3 1.5 0.9 0.7 0.4 0.4 0.4 2.1 0.4 0.4 0.4 0.4 0.4 0.4 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC024592.3 ENSG00000267740 "Novel protein" 19 5866171-5903787 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 6 "Alveolar cells type 1: 3.2;Alveolar cells type 2: 3.1;Respiratory ciliated cells: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA072209 Uncertain Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 11: Alveolar cells - Smell perception" Mitochondria "HPA072209: AB_2686495" "unprognostic (2.12e-2)" "unprognostic (2.24e-1)" "unprognostic (3.38e-1)" 1.1 1.9 0.8 0.2 0.8 1.0 1.0 0.8 1.5 1.1 1.1 1.6 0.8 0.9 0.2 2.2 0.6 0.6 2.6 0.9 0.9 1.3 2.4 1.0 0.3 0.9 1.0 1.1 1.0 0.2 1.0 0.3 1.1 1.1 0.0 0.3 1.1 0.2 2.3 1.2 1.0 0.6 0.9 1.1 1.1 0.7 1.0 0.6 0.8 1.2 0.4 1.2 1.4 0.9 3.5 4.6 1.4 3.9 2.7 0.5 1.2 2.3 3.2 4.3 3.0 1.7 2.9 2.9 2.2 1.8 2.0 2.4 0.9 2.7 0.8 1.2 1.4 0.7 1.8 3.9 1.8 1.3 1.5 1.1 4.5 3.3 1.5 1.3 1.4 4.1 1.2 3.7 0.6 2.9 4.8 1.0 2.2 1.5 2.2 4.5 1.4 3.7 2.0 1.1 2.3 3.2 1.7 2.3 2.5 0.6 1.4 4.3 2.8 0.8 2.1 5.3 4.6 3.4 4.1 1.6 2.7 4.6 1.9 4.4 4.8 2.3 3.2 4.3 2.8 4.2 3.4 3.1 5.0 4.0 3.8 3.1 2.7 3.6 3.9 6.2 4.4 8.1 0.8 0.8 0.8 1.5 0.9 0.9 0.9 1.0 1.1 0.9 1.0 0.9 0.1 3.2 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 AC093155.3 ENSG00000267561 "Novel protein" 1 86993009-87169204 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 19.3" "Cell type enriched" "Detected in single" 6 "granulocytes: 5.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.7" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.7" "Cell line enhanced" "Detected in some" "ASC TERT1: 9.4;HEL: 14.7;HMC-1: 17.9;THP-1: 12.7" "HPA043069, HPA043603" Approved Uncertain Mitochondria NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" Mitochondria "HPA043069: AB_10964127, HPA043603: AB_10963432" "unprognostic (4.41e-1)" "unprognostic (3.13e-2)" "unprognostic (2.05e-1)" "unprognostic (1.85e-2)" "unprognostic (3.17e-1)" "unprognostic (2.57e-1)" "unprognostic (4.51e-2)" "unprognostic (5.19e-3)" "unprognostic (3.60e-1)" "unprognostic (1.27e-2)" "unprognostic (1.14e-1)" "unprognostic (2.54e-1)" 19.3 1.8 2.6 3.1 3.2 0.3 7.0 1.5 5.0 4.4 1.8 3.7 2.4 2.6 2.2 3.2 1.5 4.8 8.4 2.7 1.8 1.9 1.7 5.5 2.2 1.7 1.9 6.8 1.1 0.8 0.0 5.9 1.7 0.8 3.3 0.3 2.9 2.4 1.3 0.4 3.1 4.5 1.8 2.7 1.2 3.8 1.8 1.1 1.9 3.6 1.0 4.6 0.0 2.1 0.0 0.1 0.9 2.2 2.5 9.4 0.3 0.0 0.1 0.0 0.4 0.7 0.9 0.1 0.2 0.0 0.2 0.2 0.3 0.2 0.4 0.1 0.5 14.7 0.4 0.1 0.1 0.3 17.9 1.6 0.3 0.2 0.0 0.0 0.1 0.2 0.2 0.4 0.2 0.0 0.2 0.2 0.4 1.2 0.0 0.2 0.3 0.0 0.4 0.4 0.2 0.4 0.3 0.0 0.5 0.9 0.2 12.7 0.0 0.3 0.7 0.1 1.5 1.0 4.0 0.0 0.7 0.1 0.4 0.6 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 2.6 3.2 1.5 5.0 2.7 1.8 1.7 1.9 1.7 1.8 1.8 2.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.8 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 AC131160.1 ENSG00000283765 "Presenilin associated rhomboid like" 3 183815568-183884889 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.2;skeletal muscle: 5.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "T-47d: 15.8" HPA019545 Uncertain Approved Mitochondria NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 6: T47d - Mammary gland" "Cluster 11: Alveolar cells - Smell perception" Mitochondria "HPA019545: AB_1855796" 0.5 0.5 5.0 0.4 7.2 0.5 0.3 7.7 9.2 0.2 3.1 0.5 0.1 0.1 0.0 0.6 0.2 0.0 0.6 5.0 5.7 0.2 0.2 0.3 0.2 7.0 6.6 0.3 2.0 0.4 0.1 0.2 6.7 0.2 0.5 1.0 0.3 0.4 5.5 0.6 0.3 0.4 5.2 0.2 0.4 1.3 6.1 1.7 0.3 1.6 0.2 0.4 0.2 8.3 1.0 0.4 1.3 0.4 0.3 0.3 0.1 0.9 0.4 1.3 0.5 3.3 0.1 1.1 0.3 0.8 1.7 0.0 4.2 0.8 2.1 1.4 1.5 1.6 0.9 0.8 0.0 1.0 0.3 0.6 0.6 1.0 0.0 0.8 0.0 2.7 0.3 1.1 2.0 2.5 3.1 0.7 3.2 0.0 0.5 2.2 1.1 2.1 0.3 1.6 2.3 1.4 0.7 1.2 1.4 0.2 15.8 0.2 0.0 0.1 1.6 0.3 1.5 2.0 2.6 2.1 0.5 2.2 0.6 0.0 0.2 0.6 0.1 0.1 0.1 0.2 0.1 0.2 0.0 0.0 0.1 0.1 0.2 0.0 0.2 0.2 0.0 0.1 5.0 7.2 7.7 9.2 5.0 5.7 7.0 6.6 6.7 5.2 6.1 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC139530.2 ENSG00000262660 "Novel protein" 17 81703371-81720539 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 2.4;skeletal muscle: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 5.5;Karpas-707: 6.8;MOLT-4: 18.0;SK-BR-3: 6.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022853, HPA023043, HPA023048" Approved Supported Mitochondria NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 11: Alveolar cells - Smell perception" Mitochondria "HPA022853: AB_1854099, HPA023043: AB_1854100, HPA023048: AB_2301950" "unprognostic (2.36e-3)" "unprognostic (1.17e-1)" "unprognostic (2.87e-1)" "unprognostic (3.83e-1)" 0.1 0.5 0.1 0.1 0.1 0.0 0.0 0.0 0.5 0.0 0.4 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.2 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.3 0.1 0.0 1.0 0.0 0.8 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 1.3 0.6 1.6 5.5 0.0 0.0 0.9 0.0 0.0 0.0 0.6 0.3 0.5 0.9 0.3 0.0 1.6 2.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.2 0.0 0.5 0.6 0.2 0.1 0.0 6.8 0.0 0.8 18.0 0.8 1.0 0.7 0.0 3.9 0.6 1.4 0.0 0.0 3.3 1.5 0.0 6.6 1.8 0.4 3.2 1.5 0.0 0.5 1.1 1.1 1.8 0.6 0.0 0.7 1.4 0.5 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.5 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC253536.7 ENSG00000285762 "Novel protein, AP000351.4-DDT readtrhough" 22 23971378-23980469 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Alveolar cells type 2: 15.4;Club cells: 4.3;granulocytes: 3.8;Respiratory ciliated cells: 3.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 1.1;HaCaT: 1.0;hTERT-RPE1: 2.2;RH-30: 1.2" "HPA049871, HPA074115" Uncertain Approved Mitochondria NA NA "Cluster 23: AN3-CA - Transcription regulation" "Cluster 11: Alveolar cells - Smell perception" Mitochondria "HPA049871: AB_2680926, HPA074115: " 0.1 0.3 0.1 0.3 0.1 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.3 0.3 0.1 0.0 0.3 0.2 0.0 0.4 0.4 0.1 0.5 0.0 0.4 0.3 0.0 0.0 0.2 0.8 0.0 0.5 0.0 0.2 0.0 0.0 0.2 0.2 0.1 0.3 0.0 0.1 0.0 0.0 0.1 0.5 0.2 0.0 0.0 1.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.9 1.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.3 0.0 0.0 0.8 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.3 0.1 0.4 0.4 0.3 0.0 0.3 0.5 0.0 6.4 15.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 ACAA2 DSAEC ENSG00000167315 "Acetyl-CoA acyltransferase 2" P42765 18 49782164-49813953 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1011.9" "Cell type enhanced" "Detected in all" "Distal enterocytes: 331.1;Hepatocytes: 810.5;Proximal tubular cells: 708.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042303 Approved Supported Mitochondria NA NA 3800000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA042303: AB_10794046" "unprognostic (7.94e-2)" "unprognostic (3.14e-2)" "unprognostic (2.20e-3)" "prognostic unfavorable (8.53e-4)" "unprognostic (2.92e-2)" "unprognostic (2.28e-2)" "unprognostic (7.63e-2)" "unprognostic (1.70e-1)" "unprognostic (7.97e-2)" "unprognostic (8.03e-3)" "unprognostic (1.72e-1)" "unprognostic (3.84e-1)" "prognostic favorable (1.36e-10)" "unprognostic (1.39e-1)" "unprognostic (2.24e-1)" "unprognostic (8.26e-3)" "unprognostic (3.41e-1)" 126.3 74.2 56.9 44.4 64.9 32.5 79.1 63.7 63.9 24.9 68.4 168.7 170.0 29.0 29.8 30.3 24.4 46.9 223.7 53.2 59.8 378.2 1011.9 48.9 36.6 65.1 61.4 34.8 54.1 35.1 34.9 29.6 64.0 26.4 109.6 31.9 20.3 34.0 165.3 28.0 165.2 44.5 62.8 33.6 37.4 37.7 64.3 39.9 55.8 236.6 31.9 41.6 28.6 64.2 3.9 70.5 110.0 97.5 129.9 69.5 57.4 35.2 52.4 53.6 41.2 146.3 58.9 61.1 73.5 117.5 56.7 4.8 176.8 21.0 51.4 190.5 50.4 45.5 79.0 171.4 62.5 0.7 78.3 91.7 6.7 84.8 26.2 44.6 90.0 87.7 42.5 54.7 147.5 81.8 2.7 89.7 101.5 24.8 26.7 150.8 233.0 217.6 177.7 2.8 163.4 130.9 2.7 76.2 5.6 82.1 45.7 60.0 48.1 49.8 60.5 67.8 36.4 112.3 139.7 157.3 35.0 85.7 47.1 53.0 87.4 96.1 99.2 106.5 123.0 43.2 58.3 88.7 103.2 36.3 50.2 73.2 8.3 120.0 108.1 50.1 76.4 112.7 56.9 64.9 63.7 63.9 53.2 59.8 65.1 61.4 64.0 62.8 64.3 64.2 28.4 38.5 47.3 11.8 31.4 3.6 14.2 15.5 11.4 6.7 25.0 25.5 189.9 234.4 23.7 55.2 4.2 36.5 48.2 331.1 295.4 148.5 71.2 7.9 33.9 30.0 40.1 53.6 1.7 45.7 56.0 47.3 23.9 7.7 45.1 63.3 41.4 810.5 109.6 1.7 4.6 73.0 24.4 64.8 18.5 153.9 48.1 50.6 19.6 13.1 57.2 62.2 106.1 4.5 8.7 101.8 161.2 37.2 41.2 9.8 226.6 708.0 26.4 29.5 19.7 42.1 34.9 51.1 42.7 11.1 4.8 27.0 52.2 93.0 144.8 9.6 ACAD9 "MGC14452, NPD002" ENSG00000177646 "Acyl-CoA dehydrogenase family member 9" Q9H845 3 128879596-128924003 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037716, HPA046720" Supported Enhanced Mitochondria No No "Cluster 14: Monocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA037716: AB_10673638, HPA046720: AB_2679773" "unprognostic (1.04e-1)" "unprognostic (1.28e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (3.05e-4)" "unprognostic (3.61e-1)" "unprognostic (2.83e-1)" "prognostic unfavorable (3.67e-6)" "unprognostic (1.30e-1)" "unprognostic (3.74e-1)" "unprognostic (3.25e-2)" "unprognostic (1.37e-1)" "unprognostic (6.96e-3)" "prognostic favorable (4.32e-8)" "unprognostic (1.52e-1)" "unprognostic (2.64e-2)" "unprognostic (6.56e-2)" "unprognostic (9.96e-2)" 16.7 20.5 9.0 6.1 8.5 4.7 14.5 9.6 10.2 14.4 9.1 13.6 9.0 14.6 7.7 23.2 12.9 7.3 21.9 8.3 8.7 15.6 20.6 11.0 6.6 8.2 8.7 12.9 14.4 27.7 14.6 8.4 8.4 12.1 9.4 4.1 14.2 12.0 30.4 48.0 11.2 11.1 7.4 12.2 15.9 12.5 8.7 12.1 13.6 28.7 11.2 12.9 14.5 9.0 46.2 22.6 18.0 12.6 28.7 20.7 17.5 22.4 26.2 43.6 36.8 33.3 27.1 33.3 21.1 29.5 29.0 35.5 33.8 45.9 32.8 21.2 23.1 29.3 46.8 24.4 21.6 23.9 10.6 22.5 16.8 23.6 26.7 25.1 35.8 25.2 14.4 11.4 29.5 46.5 36.7 19.0 9.9 49.3 33.8 25.5 17.4 35.1 30.9 25.1 19.0 11.6 37.0 32.9 23.2 17.4 44.5 54.8 18.2 13.2 13.4 14.2 20.3 14.5 5.8 28.3 28.3 21.4 22.7 2.4 15.1 4.9 8.3 18.3 7.8 8.1 7.6 7.3 17.5 5.4 6.2 8.0 0.7 6.8 25.2 9.9 8.3 12.1 9.0 8.5 9.6 10.2 8.3 8.7 8.2 8.7 8.4 7.4 8.7 9.0 10.4 16.0 21.7 13.1 9.3 6.2 11.4 16.7 8.6 14.1 11.9 9.5 30.5 15.7 14.8 14.7 10.4 26.2 10.5 11.7 21.5 20.6 20.2 10.4 11.5 11.2 5.4 14.3 14.3 17.8 18.8 12.9 16.8 12.9 16.5 12.0 15.7 26.7 31.5 10.1 17.7 7.4 16.2 9.5 4.0 17.3 10.2 10.8 16.0 7.5 13.4 15.0 12.3 6.0 12.2 14.1 8.7 14.7 9.5 8.1 9.4 26.3 12.0 11.9 13.1 12.7 14.9 22.6 9.6 13.5 14.2 30.6 8.2 18.1 14.3 8.4 ACADM "ACAD1, MCAD, MCADH" ENSG00000117054 "Acyl-CoA dehydrogenase medium chain" P11310 1 75724431-75787575 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 367.3;skeletal muscle: 380.0;tongue: 475.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 373.1;Distal tubular cells: 344.4;Hepatocytes: 261.2;Proximal tubular cells: 564.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 289.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006198, HPA026542" Enhanced Enhanced Mitochondria NA NA 930000 "Cluster 19: B-cells - Humoral immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA006198: AB_1078087, HPA026542: AB_1844469" "unprognostic (9.04e-3)" "unprognostic (2.36e-1)" "prognostic favorable (7.30e-4)" "unprognostic (5.09e-3)" "unprognostic (1.61e-3)" "unprognostic (5.68e-2)" "unprognostic (6.75e-2)" "unprognostic (1.11e-1)" "unprognostic (8.02e-2)" "unprognostic (4.95e-2)" "unprognostic (9.40e-3)" "unprognostic (3.35e-1)" "prognostic favorable (3.83e-8)" "unprognostic (1.27e-1)" "unprognostic (4.09e-2)" "unprognostic (3.56e-2)" "unprognostic (1.24e-1)" 81.9 82.2 25.2 24.3 25.0 17.3 69.9 26.6 42.2 29.3 30.4 46.8 103.9 20.0 25.3 51.3 30.6 27.8 217.8 24.3 25.9 295.9 367.3 22.6 42.6 26.9 26.8 35.7 35.9 66.3 19.2 16.9 25.8 26.8 49.5 21.2 31.4 26.2 380.0 14.4 75.6 25.5 26.2 27.4 52.8 35.7 25.8 29.7 38.4 475.9 44.3 32.7 21.3 25.2 25.8 20.5 61.0 26.8 53.1 42.1 17.5 48.1 40.4 46.1 38.5 38.3 39.5 289.1 40.7 34.4 39.0 22.8 54.9 41.8 57.8 113.0 25.5 94.4 58.5 58.3 36.4 80.0 23.9 50.7 23.5 39.8 22.8 35.0 36.2 56.6 102.3 60.4 50.5 9.6 96.3 40.6 50.2 80.4 49.5 118.8 83.8 30.6 77.9 70.7 33.8 43.0 38.0 111.6 102.0 43.1 32.7 107.6 20.2 29.9 29.6 26.6 78.1 38.6 62.0 128.1 25.8 67.0 35.3 15.3 14.2 19.3 17.1 20.9 27.3 40.7 17.8 21.5 21.4 24.6 20.3 23.6 0.5 25.0 20.4 23.2 19.5 19.5 25.2 25.0 26.6 42.2 24.3 25.9 26.9 26.8 25.8 26.2 25.8 25.2 42.9 57.7 58.3 29.7 56.5 27.3 41.8 69.0 44.3 39.0 49.0 40.9 373.1 52.9 63.0 58.8 25.0 35.8 39.4 42.6 344.4 37.9 55.4 27.1 32.2 36.2 40.7 67.6 51.6 26.5 19.5 47.6 26.0 25.4 44.9 61.5 43.9 261.2 75.7 30.3 46.7 38.7 63.1 45.6 22.2 24.4 46.9 38.2 51.6 19.7 32.8 53.7 29.9 36.2 36.0 21.2 49.7 45.5 74.9 24.2 88.0 564.8 106.7 30.0 0.0 38.6 43.7 76.3 86.1 46.6 27.0 15.3 39.4 72.5 46.7 35.9 ACADS "ACAD3, SCAD" ENSG00000122971 "Acyl-CoA dehydrogenase short chain" P16219 12 120725774-120740008 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 245.5;skeletal muscle: 158.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 303.1;Hepatocytes: 203.3;Paneth cells: 185.7;Proximal enterocytes: 435.0;Undifferentiated cells: 185.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 36.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004799, CAB019284, HPA022271" Enhanced Supported Mitochondria NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 3: HMC-1 - Innate immune response" "Cluster 45: Enterocytes - Digestion" Mitochondria "CAB019284: , HPA004799: AB_1844471, HPA022271: AB_1844472" "unprognostic (7.14e-2)" "unprognostic (3.03e-3)" "unprognostic (8.15e-2)" "prognostic favorable (5.05e-4)" "unprognostic (1.11e-3)" "unprognostic (5.75e-2)" "prognostic favorable (2.43e-4)" "unprognostic (5.65e-2)" "unprognostic (1.22e-1)" "unprognostic (2.14e-1)" "unprognostic (2.69e-2)" "unprognostic (4.04e-2)" "prognostic favorable (3.33e-6)" "unprognostic (1.23e-2)" "unprognostic (1.81e-1)" "unprognostic (1.21e-1)" "prognostic favorable (6.34e-5)" 50.3 52.7 13.3 11.1 15.4 14.3 40.9 13.6 16.6 11.2 13.7 74.0 84.8 10.2 0.9 14.1 10.2 8.5 90.5 12.3 13.8 51.9 245.5 13.4 6.4 14.6 14.2 8.6 33.1 4.7 9.2 7.5 13.1 13.9 21.3 0.9 19.2 7.2 158.2 13.7 73.2 5.8 14.0 31.6 34.5 20.3 16.0 6.6 21.9 79.7 3.4 18.0 12.7 14.8 3.2 11.4 0.6 9.7 12.9 5.1 11.1 4.7 4.6 6.0 4.5 8.9 8.0 0.3 11.9 3.9 2.7 5.2 6.6 2.1 0.8 16.7 8.2 8.2 3.6 19.3 9.3 0.7 36.0 15.4 3.1 2.6 0.2 1.8 6.1 20.6 6.9 0.1 2.7 6.8 11.7 19.2 2.0 10.6 4.6 8.6 4.2 2.2 11.3 18.2 1.1 6.0 9.7 0.0 15.8 0.9 7.7 13.1 6.9 0.2 4.7 4.5 0.9 15.3 9.3 4.1 10.2 7.0 4.1 8.3 15.3 7.5 13.7 16.3 9.3 6.3 12.2 14.2 13.2 8.9 15.3 14.4 1.4 19.9 10.2 11.0 14.7 12.8 13.3 15.4 13.6 16.6 12.3 13.8 14.6 14.2 13.1 14.0 16.0 14.8 18.8 12.8 13.7 10.1 6.7 6.6 9.5 21.1 4.0 1.0 25.0 14.9 44.0 27.1 13.0 18.4 0.0 78.8 9.8 303.1 50.9 35.2 23.5 12.8 8.2 13.4 45.6 38.5 2.3 32.6 31.3 18.1 28.5 10.8 19.1 12.8 19.2 203.3 55.1 1.7 2.8 105.3 20.3 21.0 8.9 36.5 21.5 15.3 17.8 0.0 26.1 13.6 18.6 3.0 3.6 26.7 185.7 18.0 7.9 8.3 435.0 94.8 7.3 0.6 6.6 13.2 12.7 41.5 8.1 9.4 4.5 75.5 11.9 140.6 185.9 12.7 ACADSB "ACAD7, SBCAD" ENSG00000196177 "Acyl-CoA dehydrogenase short/branched chain" P45954 10 123008979-123058290 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 360.1" "Cell type enhanced" "Detected in all" "Hepatocytes: 499.5;Proximal tubular cells: 137.9" "Cancer enhanced" "Detected in all" "liver cancer: 32.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 54.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041458, HPA063555" Enhanced Supported Mitochondria NA NA 37000 "Cluster 2: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Mitochondria "HPA041458: AB_2677491, HPA063555: " "unprognostic (1.53e-2)" "unprognostic (1.31e-1)" "unprognostic (3.91e-3)" "unprognostic (2.02e-1)" "unprognostic (1.25e-1)" "unprognostic (4.87e-2)" "unprognostic (4.15e-2)" "unprognostic (1.32e-3)" "unprognostic (1.30e-1)" "unprognostic (3.67e-1)" "prognostic favorable (3.40e-4)" "unprognostic (9.37e-3)" "prognostic favorable (6.37e-12)" "unprognostic (2.69e-1)" "unprognostic (7.20e-2)" "unprognostic (1.60e-3)" "unprognostic (7.14e-2)" 14.8 27.4 8.0 7.1 8.5 3.8 23.9 13.9 10.3 7.8 13.1 15.9 52.4 9.9 7.7 12.6 9.7 7.6 38.5 8.6 6.7 90.2 360.1 12.7 8.2 6.3 7.6 12.8 15.8 33.4 8.8 5.1 6.8 22.7 16.8 12.4 15.7 11.2 42.4 9.8 11.0 8.5 5.9 6.4 14.0 8.4 8.0 7.4 12.3 69.1 10.3 10.8 8.1 8.4 15.4 10.9 7.9 14.5 10.6 13.1 7.0 9.3 18.8 9.2 9.1 9.6 4.9 16.0 6.3 7.9 5.6 6.3 12.5 6.5 15.1 10.6 12.9 8.3 3.3 54.8 7.5 12.0 7.6 9.7 6.5 5.8 5.3 13.5 9.0 13.2 8.1 11.5 11.5 7.1 11.4 9.8 4.8 8.5 6.7 13.4 16.6 5.1 13.1 16.9 1.4 9.1 14.3 4.2 14.4 7.5 12.9 5.8 9.5 4.9 4.4 11.4 11.4 12.9 15.5 8.5 7.6 11.1 3.8 17.4 4.5 11.8 8.8 4.7 10.2 5.5 8.1 7.6 6.4 5.7 7.4 8.3 2.9 8.5 2.9 3.8 7.1 5.7 8.0 8.5 13.9 10.3 8.6 6.7 6.3 7.6 6.8 5.9 8.0 8.4 7.7 28.9 53.1 29.4 11.6 9.3 9.2 8.2 14.2 17.4 58.6 27.8 80.7 37.1 21.1 11.0 10.4 20.1 8.7 11.2 46.9 7.3 7.0 6.8 9.1 8.2 12.1 21.4 39.8 4.8 3.5 10.6 10.7 18.8 3.8 29.1 15.4 499.5 7.3 21.9 49.6 13.7 26.4 17.4 5.9 8.1 13.4 7.1 7.2 12.2 7.9 12.0 7.2 15.6 38.3 4.6 13.1 10.9 9.1 19.8 9.2 137.9 15.2 7.7 19.7 12.3 11.0 8.5 3.7 14.7 13.8 30.1 13.3 18.9 18.3 12.0 ACAT1 "ACAT, THIL" ENSG00000075239 "Acetyl-CoA acetyltransferase 1" P24752 11 108116695-108147603 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 622.7;liver: 969.5" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 508.4;Distal tubular cells: 698.5;Hepatocytes: 663.4;Proximal tubular cells: 1484.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 420.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004428, HPA007569" Enhanced Enhanced Mitochondria NA NA 1400000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA004428: AB_1078088, HPA007569: AB_1844482" "unprognostic (3.70e-3)" "unprognostic (2.23e-2)" "unprognostic (7.84e-3)" "unprognostic (4.65e-2)" "unprognostic (3.05e-2)" "unprognostic (1.12e-1)" "prognostic favorable (1.43e-5)" "unprognostic (3.59e-3)" "unprognostic (1.26e-1)" "unprognostic (5.20e-2)" "unprognostic (2.64e-2)" "unprognostic (1.13e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.96e-1)" "unprognostic (1.68e-1)" "unprognostic (8.06e-2)" "unprognostic (6.62e-3)" 135.4 151.3 45.2 24.3 45.3 38.4 56.9 47.1 60.1 41.0 91.8 96.3 103.9 44.0 34.1 45.0 39.1 25.6 289.4 42.7 46.8 622.7 969.5 43.7 28.2 44.8 45.2 64.7 110.6 95.9 30.9 24.7 45.2 45.6 85.6 26.2 104.1 60.2 461.1 45.3 53.2 57.1 46.7 29.3 81.9 66.3 45.6 19.1 65.5 410.8 29.7 44.1 34.6 47.7 76.9 57.7 48.2 139.3 155.9 138.7 25.1 71.7 78.8 77.7 91.7 168.1 77.3 41.3 116.8 83.6 119.7 78.1 142.3 70.3 83.3 84.9 114.6 117.4 64.6 163.9 107.6 112.9 64.9 124.6 77.1 69.2 127.4 91.5 85.0 92.3 172.1 61.8 128.6 45.8 57.4 122.4 48.2 103.1 135.0 88.1 96.9 420.4 114.7 50.4 75.7 88.1 111.6 152.7 83.0 37.0 132.2 97.6 87.4 83.2 44.5 73.5 88.8 18.9 57.8 77.7 37.6 233.1 59.6 1.4 17.1 4.7 25.3 25.5 29.9 29.2 28.8 30.0 33.5 13.8 25.5 22.4 1.8 13.4 27.8 11.3 35.7 23.4 45.2 45.3 47.1 60.1 42.7 46.8 44.8 45.2 45.2 46.7 45.6 47.7 50.5 54.5 91.8 17.9 37.2 43.1 52.2 48.9 23.9 30.1 34.6 29.6 508.4 78.6 33.5 104.8 27.1 39.9 29.2 125.0 698.5 43.1 345.7 62.2 42.1 62.5 30.0 74.7 35.1 60.5 41.5 57.1 29.0 25.7 27.8 48.6 99.2 663.4 97.9 38.7 37.8 38.5 97.6 73.6 27.8 65.3 66.5 39.1 58.7 30.0 50.1 39.1 25.7 22.6 26.5 33.8 93.8 82.4 52.7 27.8 51.4 1484.0 101.8 28.8 65.7 54.2 69.2 172.7 27.2 39.2 48.4 25.2 38.1 61.6 84.5 24.4 ACO2 ACONM ENSG00000100412 "Aconitase 2" Q99798 22 41447830-41529273 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Lyase "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 567.7;skeletal muscle: 660.4;tongue: 695.8" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 374.2;Proximal tubular cells: 285.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001097 Enhanced Approved Approved Mitochondria NA NA 2000000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA001097: AB_1078092" "unprognostic (1.95e-1)" "unprognostic (2.50e-2)" "unprognostic (2.35e-2)" "unprognostic (3.06e-2)" "unprognostic (6.51e-2)" "unprognostic (1.26e-1)" "unprognostic (3.99e-2)" "unprognostic (6.54e-2)" "unprognostic (1.20e-2)" "unprognostic (7.32e-2)" "unprognostic (1.64e-2)" "unprognostic (6.07e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.46e-2)" "unprognostic (9.60e-2)" "unprognostic (6.45e-2)" "unprognostic (1.12e-2)" 88.8 81.6 154.2 38.6 152.2 32.0 52.4 153.0 190.0 39.5 160.1 94.4 162.9 42.0 26.1 60.4 53.6 36.5 567.7 155.2 153.1 138.9 73.9 40.7 40.5 146.1 145.3 30.8 53.8 233.8 33.6 30.5 147.8 41.2 69.6 46.9 72.0 49.5 660.4 45.5 158.5 43.7 152.5 44.7 110.2 35.1 186.3 38.0 53.7 695.8 43.3 52.5 42.4 159.6 47.2 55.8 56.5 116.3 101.2 69.8 78.7 43.7 60.9 79.0 71.9 81.2 63.5 115.7 72.2 70.6 60.3 109.8 108.8 88.3 42.8 75.8 80.2 51.0 73.7 95.0 86.7 147.8 77.8 120.8 64.4 78.9 83.2 61.7 81.2 61.5 72.9 118.4 65.4 91.7 73.7 47.9 37.0 282.6 115.1 102.3 37.8 162.1 106.8 97.3 37.8 33.9 112.2 128.7 82.0 44.9 74.9 74.7 55.5 60.0 68.7 50.2 45.0 64.7 92.1 80.6 102.0 64.0 66.5 10.3 52.9 18.1 32.0 76.4 29.3 49.4 25.5 34.9 69.0 46.4 29.2 30.8 9.0 39.4 97.1 24.0 41.2 58.6 154.2 152.2 153.0 190.0 155.2 153.1 146.1 145.3 147.8 152.5 186.3 159.6 26.3 25.6 31.8 45.4 49.4 18.7 54.5 102.7 31.3 60.6 28.0 23.2 9.1 64.3 63.5 60.7 81.3 100.3 33.3 190.8 131.0 58.3 14.5 37.2 17.7 26.1 53.2 30.3 28.8 42.6 60.0 24.0 77.5 37.1 40.6 56.7 20.7 64.6 91.5 53.8 34.0 99.1 89.5 35.5 26.4 8.9 24.2 39.2 35.6 7.5 68.3 73.9 34.0 12.1 20.9 43.9 103.5 27.8 63.2 34.4 374.2 285.7 59.2 73.5 59.2 28.6 38.4 26.4 38.2 35.8 16.1 193.2 30.7 54.4 113.6 64.9 ACOT1 "ACH2, CTE-1, LACH2" ENSG00000184227 "Acyl-CoA thioesterase 1" Q86TX2 14 73537143-73543796 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 44.4" "Cell type enhanced" "Detected in some" "Astrocytes: 10.7;Cardiomyocytes: 51.5;Excitatory neurons: 13.8;Inhibitory neurons: 12.0;Oligodendrocyte precursor cells: 8.5;Oligodendrocytes: 15.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 30.5;T-47d: 49.8" HPA043705 Approved Approved Mitochondria NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA043705: AB_2678626" "unprognostic (4.74e-3)" "unprognostic (3.81e-3)" "unprognostic (7.65e-2)" "unprognostic (8.66e-2)" "unprognostic (1.22e-1)" "unprognostic (1.29e-1)" "unprognostic (4.54e-2)" "unprognostic (1.29e-2)" "unprognostic (1.53e-1)" "unprognostic (1.73e-2)" "unprognostic (1.84e-1)" "unprognostic (4.16e-1)" "prognostic favorable (5.09e-8)" "unprognostic (1.35e-3)" "unprognostic (4.60e-2)" "unprognostic (1.75e-1)" "unprognostic (1.43e-1)" 15.1 12.9 10.4 3.6 10.2 2.4 13.0 9.3 11.3 5.7 8.4 12.9 10.8 13.2 11.6 3.4 7.3 3.5 18.6 10.1 9.7 25.9 44.4 7.3 2.3 9.2 10.1 3.5 3.0 2.2 2.0 2.9 9.6 5.6 5.4 2.9 5.1 9.3 19.6 8.9 11.8 20.9 9.5 2.6 6.4 4.2 11.1 2.5 3.6 29.3 2.1 9.5 4.0 9.6 10.7 9.0 3.3 0.7 15.2 9.1 0.1 2.9 8.5 7.0 12.6 3.9 6.9 0.0 0.4 5.8 0.9 6.0 0.0 1.4 3.4 4.5 2.8 4.6 2.8 30.5 14.4 0.1 5.1 12.0 0.6 5.6 0.0 0.7 3.2 0.0 0.0 0.0 5.5 4.7 0.6 1.0 3.4 1.4 4.9 9.5 6.8 0.2 6.9 8.7 4.9 6.4 9.0 20.2 12.2 0.9 49.8 9.9 4.2 5.2 7.5 4.2 0.7 0.1 0.0 2.6 6.2 0.0 6.8 0.7 0.9 0.7 4.1 1.1 3.5 2.6 3.9 3.4 3.8 1.9 3.5 3.9 0.1 3.5 1.1 2.2 5.1 2.6 10.4 10.2 9.3 11.3 10.1 9.7 9.2 10.1 9.6 9.5 11.1 9.6 0.2 0.0 3.2 10.7 0.0 0.0 0.1 0.6 1.8 0.0 0.4 0.4 51.5 0.0 0.4 0.0 0.0 0.7 1.3 0.2 0.0 0.4 0.6 0.3 0.3 0.7 0.0 2.7 13.8 8.0 0.3 2.6 0.0 0.3 0.0 0.1 0.0 1.1 0.9 0.0 12.0 0.0 2.0 0.3 0.0 0.0 0.0 0.5 1.8 3.7 0.0 0.0 0.0 8.5 15.1 2.6 0.0 0.4 0.3 0.0 0.0 3.7 0.3 0.0 0.0 0.0 3.6 0.1 0.2 0.6 0.0 0.8 0.2 0.0 0.2 0.0 ACOT2 "Mte1, ZAP128" ENSG00000119673 "Acyl-CoA thioesterase 2" P49753 14 73567620-73575658 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 118.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 50.0;Exocrine glandular cells: 33.2;Proximal tubular cells: 36.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 62.4" "HPA043705, HPA060170" Enhanced Approved Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA043705: AB_2678626, HPA060170: AB_2732642" "unprognostic (4.44e-3)" "unprognostic (1.68e-2)" "unprognostic (3.17e-1)" "unprognostic (8.66e-2)" "unprognostic (1.78e-1)" "unprognostic (1.55e-1)" "unprognostic (2.78e-2)" "unprognostic (6.61e-2)" "unprognostic (4.10e-2)" "unprognostic (9.21e-2)" "unprognostic (6.42e-2)" "unprognostic (1.64e-1)" "prognostic favorable (2.28e-6)" "unprognostic (1.66e-3)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (4.35e-1)" 92.3 47.7 10.0 7.0 10.3 5.6 48.9 9.2 12.4 17.1 12.2 42.2 24.7 42.9 10.7 10.9 24.1 6.1 94.5 10.1 9.5 49.4 118.9 17.3 4.7 8.8 9.4 11.7 12.8 22.4 8.3 4.4 8.2 17.8 11.1 4.1 17.8 11.1 114.0 13.1 24.5 22.8 9.2 11.4 22.5 12.0 13.0 3.7 14.5 50.0 3.3 31.2 13.3 9.0 22.8 25.0 4.9 22.1 21.3 7.9 1.0 13.7 31.5 21.9 28.6 18.1 12.6 0.1 9.7 7.0 10.3 12.7 0.0 1.2 11.4 33.1 31.6 16.0 7.6 62.4 14.5 0.1 43.3 19.5 0.0 7.6 0.1 21.0 9.5 0.0 0.0 0.1 18.7 7.4 2.5 18.2 7.5 2.3 37.8 37.2 21.9 0.3 8.0 9.5 21.6 27.3 33.1 24.3 29.6 2.1 51.1 12.7 17.0 17.9 47.2 11.8 13.0 0.0 0.1 9.5 15.8 0.1 18.2 3.5 5.9 3.1 22.1 7.0 15.8 15.0 20.2 16.6 21.9 12.4 17.8 19.9 0.2 15.3 6.5 13.6 31.3 13.6 10.0 10.3 9.2 12.4 10.1 9.5 8.8 9.4 8.2 9.2 13.0 9.0 4.3 0.0 6.4 3.3 6.6 1.7 1.0 5.9 16.5 1.1 5.2 4.2 50.0 7.2 3.0 7.3 10.4 6.1 3.0 20.1 13.7 20.9 1.5 1.4 1.9 4.0 15.7 8.4 2.9 33.2 3.2 7.0 11.7 2.1 13.4 1.9 4.2 27.7 14.9 1.7 3.1 15.5 10.2 3.8 1.6 1.1 5.9 5.6 5.4 1.0 18.5 5.5 7.2 3.0 1.7 21.8 8.6 8.2 7.9 0.4 27.5 36.5 3.3 4.9 6.6 1.4 9.8 0.3 4.8 8.5 0.4 8.2 5.8 1.7 18.8 0.4 ACSS3 FLJ21963 ENSG00000111058 "Acyl-CoA synthetase short chain family member 3" Q9H6R3 12 80936414-81261210 "Enzymes, Metabolic proteins, Predicted membrane proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 40.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 46.5;Astrocytes: 167.8;Early spermatids: 52.9;Hepatocytes: 53.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 14 "basophil: 7.0;neutrophil: 2.2" "Lineage enriched" "Detected in single" 70 "granulocytes: 7.0" "Cell line enhanced" "Detected in many" "ASC diff: 14.3;ASC TERT1: 16.1;Hep G2: 42.6;hTERT-RPE1: 14.0;RH-30: 19.1;SK-BR-3: 18.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039353, HPA047956, HPA061517" Approved Supported Mitochondria NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 64: Astrocytes - Nervous system maintenance" Mitochondria "HPA039353: AB_2676460, HPA047956: AB_2680223, HPA061517: AB_2684549" "unprognostic (8.59e-2)" "unprognostic (9.29e-4)" "unprognostic (1.47e-1)" "unprognostic (9.37e-3)" "unprognostic (2.46e-2)" "unprognostic (2.21e-1)" "unprognostic (9.25e-2)" "unprognostic (1.18e-1)" "unprognostic (1.34e-1)" "unprognostic (7.18e-3)" "unprognostic (1.68e-1)" "unprognostic (7.79e-2)" "prognostic favorable (0.00e+0)" "unprognostic (6.16e-4)" "unprognostic (1.63e-1)" "unprognostic (2.00e-1)" "unprognostic (2.00e-4)" 22.7 14.5 5.2 1.5 5.1 0.1 7.3 5.2 5.3 8.3 9.3 2.2 0.7 9.1 12.1 1.5 8.0 8.1 6.8 4.7 4.9 25.9 40.0 6.4 1.5 5.5 6.4 16.7 2.0 13.7 4.4 4.0 5.2 5.7 1.0 4.8 12.1 5.5 3.5 1.7 1.5 6.3 4.9 2.1 1.4 2.3 6.5 1.1 8.8 5.7 1.1 2.8 5.0 5.5 0.0 0.2 3.4 0.0 14.3 16.1 0.1 2.2 11.0 1.7 1.9 0.4 0.1 0.0 0.0 5.0 5.2 0.1 0.0 0.0 1.0 0.0 2.2 0.0 0.0 42.6 4.8 0.1 0.0 10.8 0.0 0.5 0.0 14.0 0.4 0.0 0.0 0.0 7.8 1.0 0.1 0.2 4.8 0.0 0.0 0.0 19.1 2.7 0.1 0.1 3.1 0.0 0.0 18.0 0.1 7.1 7.9 0.5 0.0 2.8 2.7 0.2 1.2 0.1 0.1 0.1 3.5 0.0 3.4 7.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 5.2 5.1 5.2 5.3 4.7 4.9 5.5 6.4 5.2 4.9 6.5 5.5 1.3 22.4 46.5 167.8 0.2 0.9 9.5 0.0 2.2 37.8 5.6 3.0 21.8 14.3 3.2 12.9 4.2 1.5 0.1 0.1 5.9 6.4 52.9 3.9 14.8 1.5 0.0 0.0 1.5 2.9 0.8 12.1 0.0 2.7 0.0 8.8 1.8 53.6 0.7 28.6 1.6 0.1 0.0 3.2 0.6 9.4 23.9 0.8 0.0 35.6 0.1 16.4 0.0 16.6 0.7 0.1 0.1 23.7 0.0 3.0 1.1 31.7 3.7 5.3 6.6 18.6 9.9 4.6 0.6 0.4 0.1 0.5 0.6 13.2 1.2 3.7 ADCY1 "AC1, DFNB44" ENSG00000164742 "Adenylate cyclase 1" Q08828 7 45574140-45723116 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, cAMP biosynthesis" "Calmodulin-binding, Lyase" "Cancer-related genes, Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 33.7;liver: 19.2;retina: 53.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 521.3;Excitatory neurons: 147.2;Inhibitory neurons: 117.9;Rod photoreceptor cells: 174.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-HME1: 22.2;SH-SY5Y: 25.5;SK-MEL-30: 30.1;WM-115: 17.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018364, HPA068274" Uncertain Approved Mitochondria NA NA "Cluster 58: Brain - Synaptic function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 9: Photoreceptor cells - Phototransduction" Mitochondria "CAB018364: AB_2223098, HPA068274: " "unprognostic (9.41e-3)" "unprognostic (7.30e-4)" "unprognostic (9.31e-2)" "unprognostic (2.98e-1)" "unprognostic (4.18e-2)" "unprognostic (3.07e-3)" "unprognostic (1.32e-1)" "unprognostic (7.31e-2)" "unprognostic (1.64e-3)" "unprognostic (2.89e-1)" "unprognostic (7.73e-3)" "unprognostic (1.54e-1)" "unprognostic (4.74e-6)" "unprognostic (2.49e-1)" "unprognostic (7.65e-3)" "unprognostic (2.87e-1)" "unprognostic (2.23e-1)" 1.9 1.8 13.7 0.3 22.4 0.0 4.7 15.4 33.7 5.3 0.0 0.4 0.2 1.8 0.5 0.6 2.0 0.6 2.9 31.9 0.0 1.9 19.2 0.6 0.4 1.2 0.9 0.9 3.3 1.9 2.6 0.4 1.1 2.8 0.4 53.0 0.3 1.2 7.7 0.4 0.3 0.9 0.0 1.7 1.1 2.8 4.0 0.3 2.4 8.5 0.3 0.8 1.3 24.5 0.8 5.9 2.1 3.2 4.1 0.1 4.0 0.2 0.0 0.8 0.3 0.6 0.0 0.0 0.2 0.2 5.8 1.9 3.8 0.3 0.1 10.7 2.7 0.0 0.0 0.6 0.0 0.2 0.1 4.9 2.8 0.5 22.2 0.0 0.1 8.6 0.3 7.0 0.3 7.1 0.0 0.0 8.3 5.1 0.0 0.0 0.0 11.7 0.0 5.7 13.4 25.5 2.1 0.0 30.1 3.1 2.0 3.5 0.0 0.6 4.2 0.5 3.6 0.0 0.0 0.0 0.0 0.0 17.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.7 22.4 15.4 33.7 31.9 0.0 1.2 0.9 1.1 0.0 4.0 24.5 3.5 0.0 0.0 30.7 0.3 0.3 0.6 0.0 0.0 43.8 10.6 5.7 11.4 2.8 0.0 0.0 521.3 0.1 0.3 0.5 1.9 0.0 2.9 1.0 23.1 10.8 31.2 0.0 147.2 0.9 0.2 4.2 0.0 0.7 0.0 0.2 15.7 52.3 0.3 42.1 117.9 1.0 2.0 3.2 0.4 0.7 1.8 0.2 3.6 17.8 0.0 13.8 0.0 63.3 4.0 0.5 0.1 7.5 0.1 2.6 0.0 0.4 0.0 174.4 0.0 2.3 8.8 0.5 6.8 0.1 0.1 0.0 0.6 0.6 0.6 0.3 ADGRF4 "FLJ38076, GPR115, PGR18" ENSG00000153294 "Adhesion G protein-coupled receptor F4" Q8IZF3 6 47685864-47722021 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 18.3;skin 1: 38.8" "Cell type enhanced" "Detected in some" "Extravillous trophoblasts: 15.1;Pancreatic endocrine cells: 20.5;Prostatic glandular cells: 6.0;Squamous epithelial cells: 14.4;Syncytiotrophoblasts: 7.3;Urothelial cells: 20.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 8.2" "Region enriched" "Detected in single" 5 "hypothalamus: 1.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 13.2;HBEC3-KT: 21.0;hTCEpi: 31.8;OE19: 18.4;U-87 MG: 26.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" "HPA007131, HPA007158" Enhanced Uncertain Mitochondria NA NA "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" Mitochondria "HPA007131: AB_2667756, HPA007158: AB_1849254" "unprognostic (1.40e-2)" "unprognostic (7.06e-3)" "unprognostic (2.11e-1)" "unprognostic (4.68e-2)" "unprognostic (3.79e-2)" "unprognostic (3.77e-2)" "unprognostic (2.04e-3)" "unprognostic (2.64e-1)" "unprognostic (3.47e-1)" "prognostic unfavorable (5.52e-4)" "unprognostic (2.86e-1)" "unprognostic (1.66e-8)" "unprognostic (1.62e-3)" "unprognostic (2.01e-1)" "unprognostic (1.46e-1)" "unprognostic (2.25e-1)" 0.2 0.7 0.0 0.2 0.0 0.0 2.2 0.4 0.1 4.7 0.0 1.2 0.0 0.3 0.0 18.3 1.1 0.7 0.6 0.0 1.9 0.7 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.1 2.0 0.0 0.2 1.5 0.0 2.4 0.0 0.6 38.8 0.2 0.1 0.0 0.0 0.0 0.5 0.1 0.2 0.0 0.9 4.1 4.3 9.6 0.0 8.9 1.2 0.0 0.0 0.0 0.0 1.0 0.0 5.1 0.1 0.0 2.4 0.0 0.0 0.0 0.0 8.2 13.2 0.0 21.0 0.2 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 31.8 0.4 0.7 1.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 18.4 1.2 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.4 1.8 0.1 0.2 0.0 0.0 0.0 0.8 0.1 1.0 0.0 0.0 0.0 0.0 26.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 1.9 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.6 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 1.2 0.0 4.4 0.0 3.5 0.7 1.6 0.3 0.2 0.0 0.0 0.6 3.4 15.1 0.4 0.0 3.8 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.5 0.5 0.0 0.0 6.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 14.4 0.0 7.3 0.0 0.0 0.1 20.5 AFG3L2 "SCA28, SPAX5" ENSG00000141385 "AFG3 like matrix AAA peptidase subunit 2" Q9Y4W6 18 12328944-12377227 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004479, HPA004480" Enhanced Supported Mitochondria NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA004479: AB_1078109, HPA004480: AB_1078108" "unprognostic (1.11e-1)" "unprognostic (7.49e-2)" "unprognostic (1.67e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (1.31e-1)" "unprognostic (5.06e-3)" "unprognostic (1.61e-1)" "unprognostic (2.33e-1)" "unprognostic (5.35e-2)" "unprognostic (1.54e-2)" "unprognostic (4.05e-2)" "unprognostic (3.00e-2)" "prognostic favorable (6.05e-14)" "unprognostic (5.90e-2)" "unprognostic (9.41e-2)" "unprognostic (5.74e-3)" "unprognostic (2.22e-1)" 26.1 25.9 16.4 21.9 17.0 32.4 29.2 18.2 19.0 24.1 30.8 60.8 79.9 22.1 17.5 41.5 23.8 18.3 88.0 17.0 18.7 62.7 51.0 21.8 23.7 17.7 16.6 24.1 41.1 76.0 18.6 23.5 18.8 24.6 54.1 20.3 30.8 24.4 145.4 29.8 58.7 25.4 15.8 18.5 39.1 18.5 19.0 24.3 39.2 155.8 31.0 30.9 19.6 17.6 56.5 56.6 39.7 44.8 45.2 48.6 52.7 61.9 61.1 86.6 63.1 88.1 34.1 161.3 66.3 56.6 76.8 55.6 101.4 71.3 70.3 38.1 43.5 48.5 59.3 83.5 61.1 185.0 69.8 54.3 76.3 82.1 107.7 47.8 64.0 57.0 111.3 92.8 43.6 89.0 66.7 58.5 55.3 277.4 41.9 74.0 125.1 135.2 74.9 123.6 73.7 51.3 97.0 103.8 90.0 50.5 47.8 84.5 49.0 102.4 88.6 98.7 81.7 64.7 80.7 104.1 56.2 71.4 48.0 3.8 16.5 12.4 11.6 17.6 13.9 14.0 13.8 17.9 21.8 10.3 17.2 20.2 1.1 28.4 16.2 11.5 9.5 13.4 16.4 17.0 18.2 19.0 17.0 18.7 17.7 16.6 18.8 15.8 19.0 17.6 24.3 41.7 49.2 23.2 36.6 22.2 45.3 21.5 42.7 50.2 36.5 36.2 74.9 50.1 28.1 35.0 50.1 58.5 29.1 85.2 72.4 39.5 5.5 37.8 52.3 27.7 39.1 61.0 21.1 37.4 37.9 31.2 53.5 46.1 14.5 41.3 21.8 85.6 37.0 30.3 26.8 82.6 18.3 32.6 14.4 5.5 32.9 34.2 23.2 12.2 27.6 26.9 40.2 14.1 17.7 47.8 43.1 30.1 38.8 43.1 88.7 100.0 22.1 58.3 26.3 53.6 26.9 50.9 65.0 75.8 31.3 92.8 28.4 60.8 94.9 38.2 AFMID "DKFZp686F03259, KF" ENSG00000183077 Arylformamidase Q63HM1 17 78187317-78207701 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Tryptophan catabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 173.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 118.3;Proximal tubular cells: 105.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 6.4;intermediate monocyte: 16.7;memory B-cell: 5.4;myeloid DC: 7.6;non-classical monocyte: 11.0;plasmacytoid DC: 5.1" "Group enriched" "Detected in all" 5 "B-cells: 5.4;dendritic cells: 7.6;monocytes: 16.7" "Cell line enhanced" "Detected in all" "Hep G2: 186.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023861, HPA026536" Uncertain Approved Mitochondria NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA023861: AB_1844636, HPA026536: AB_1844637" "unprognostic (3.55e-2)" "unprognostic (1.54e-2)" "unprognostic (1.53e-1)" "unprognostic (2.65e-3)" "unprognostic (2.06e-1)" "unprognostic (4.73e-2)" "unprognostic (2.78e-1)" "unprognostic (1.83e-1)" "unprognostic (1.49e-3)" "unprognostic (1.53e-2)" "unprognostic (5.78e-2)" "unprognostic (9.59e-3)" "unprognostic (9.12e-2)" "unprognostic (1.80e-2)" "unprognostic (1.43e-1)" "unprognostic (1.94e-1)" "unprognostic (7.79e-2)" 14.6 7.6 52.8 11.7 76.1 10.8 65.5 67.3 66.2 15.2 35.5 15.8 17.9 15.3 13.9 18.7 22.9 19.0 22.5 52.6 60.5 88.8 173.2 27.1 12.0 74.4 71.3 31.9 59.3 9.1 9.1 26.7 66.8 28.3 18.8 4.0 38.7 18.4 19.2 32.9 15.5 13.4 56.6 14.6 22.1 13.2 68.6 8.9 15.0 14.4 13.4 13.2 19.0 114.8 21.3 29.4 25.4 23.3 27.9 32.5 13.7 29.8 16.8 20.4 24.5 31.5 17.2 65.8 19.2 22.8 11.9 17.8 43.5 26.0 28.5 41.9 34.6 53.2 35.2 186.5 24.4 44.4 26.2 43.8 26.9 23.9 31.0 33.5 38.8 19.6 54.7 22.4 16.0 20.9 34.0 67.2 20.9 51.1 49.8 38.3 25.9 79.2 27.9 19.3 56.2 41.5 25.5 75.5 24.4 25.1 22.8 42.3 19.3 31.2 20.5 19.9 21.4 33.8 24.2 68.0 25.7 21.5 8.2 1.7 6.4 0.8 0.7 16.7 1.2 5.4 1.1 1.2 7.6 2.1 0.6 0.6 1.8 1.9 11.0 5.1 1.1 1.8 52.8 76.1 67.3 66.2 52.6 60.5 74.4 71.3 66.8 56.6 68.6 114.8 17.9 16.0 16.0 0.7 9.7 26.4 19.8 11.5 79.6 1.2 44.7 34.3 13.2 58.6 12.1 64.4 4.2 12.9 2.1 15.1 17.6 11.5 0.2 21.3 14.5 16.7 13.1 11.3 7.7 8.5 11.2 18.6 23.9 23.8 2.5 9.5 17.9 118.3 10.1 1.7 4.0 26.8 10.2 20.9 20.7 2.7 22.4 21.9 30.2 6.5 8.8 1.6 2.1 3.0 74.2 7.8 27.6 21.8 25.4 15.7 17.8 105.8 14.7 1.7 0.0 15.2 18.1 1.5 13.3 52.1 41.1 11.5 4.3 21.6 30.6 14.5 AGPAT5 "FLJ11210, LPAAT-e, LPAAT-epsilon" ENSG00000155189 "1-acylglycerol-3-phosphate O-acyltransferase 5" Q9NUQ2 8 6708642-6761503 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 83.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010644, HPA010950, HPA011646" Approved Supported Mitochondria NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 43: Testis - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 44: Endometrium - Transcription" Mitochondria "HPA010644: AB_1844647, HPA010950: AB_1844648, HPA011646: " "unprognostic (1.05e-3)" "unprognostic (4.69e-1)" "prognostic favorable (8.82e-4)" "unprognostic (2.05e-2)" "unprognostic (2.99e-1)" "unprognostic (1.44e-2)" "prognostic unfavorable (4.57e-4)" "unprognostic (4.92e-1)" "unprognostic (1.82e-1)" "unprognostic (2.98e-2)" "unprognostic (6.33e-2)" "unprognostic (2.91e-1)" "unprognostic (6.62e-2)" "unprognostic (2.83e-1)" "unprognostic (3.60e-1)" "unprognostic (1.53e-2)" "unprognostic (5.09e-3)" 5.4 11.8 6.7 2.9 6.8 2.3 4.9 7.2 8.3 6.5 6.1 8.0 3.1 6.6 7.9 8.5 7.4 1.8 3.4 6.6 7.4 7.2 10.0 4.5 4.1 7.8 7.4 5.8 6.4 3.3 10.3 4.1 7.6 6.0 4.2 5.2 5.0 5.6 11.3 3.5 6.7 2.9 7.6 4.8 6.9 22.5 7.1 4.7 4.0 2.7 3.7 4.7 5.8 8.7 8.5 7.0 15.3 6.8 3.4 5.2 9.4 4.3 4.6 7.9 7.0 4.6 7.3 21.8 3.2 3.3 10.8 11.0 9.5 9.5 11.2 4.6 6.6 27.4 7.0 10.5 9.1 12.4 10.0 7.6 10.0 6.7 9.8 8.2 13.6 9.5 19.9 10.7 11.4 6.3 23.5 20.1 20.4 13.6 5.8 15.0 15.0 8.2 7.9 13.1 24.4 14.8 4.1 7.9 9.4 8.1 3.6 20.5 5.5 10.8 5.4 4.4 12.4 4.0 12.8 11.3 7.3 13.8 12.9 1.8 1.9 1.2 0.7 2.4 1.6 4.4 1.3 1.4 1.2 5.1 0.9 1.1 0.2 2.7 2.2 4.4 1.2 1.4 6.7 6.8 7.2 8.3 6.6 7.4 7.8 7.4 7.6 7.6 7.1 8.7 15.7 3.2 4.4 58.8 46.5 9.1 18.8 14.2 19.4 7.8 14.2 10.5 5.8 11.5 9.0 7.3 2.1 9.4 23.5 17.4 3.9 11.2 40.0 30.0 27.9 22.3 22.1 50.0 45.0 10.0 14.2 10.4 27.0 83.6 18.9 10.6 10.4 41.9 12.2 6.7 46.8 10.1 14.2 16.0 4.6 34.7 15.8 12.6 7.2 33.7 7.5 42.3 6.2 56.8 60.2 10.2 16.0 15.4 22.3 30.4 9.8 22.5 14.6 9.8 6.6 14.0 24.7 26.2 10.9 30.9 10.4 18.5 17.4 15.0 25.2 11.9 AIFM1 "AIF, AUNX1, CMTX4, DFNX5, NAMSD, PDCD8" ENSG00000156709 "Apoptosis inducing factor mitochondria associated 1" O95831 X 130124666-130165879 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "DNA-binding, Oxidoreductase" "Charcot-Marie-Tooth disease, Deafness, Disease variant, Dwarfism, Mental retardation, Neurodegeneration, Neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 165.4;Proximal tubular cells: 326.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003764, HPA030611" Enhanced Supported Mitochondria NA NA 230000 "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "CAB003764: AB_289587, HPA030611: AB_2673549" "unprognostic (3.00e-3)" "unprognostic (1.34e-2)" "unprognostic (1.34e-1)" "unprognostic (1.22e-1)" "unprognostic (2.10e-2)" "unprognostic (3.15e-3)" "unprognostic (1.46e-1)" "unprognostic (1.14e-2)" "unprognostic (1.43e-1)" "unprognostic (3.11e-2)" "unprognostic (2.54e-3)" "unprognostic (2.81e-3)" "prognostic favorable (4.42e-10)" "unprognostic (1.76e-2)" "unprognostic (1.14e-1)" "unprognostic (5.04e-2)" "unprognostic (2.11e-2)" 21.0 65.2 10.5 17.6 11.2 11.8 17.8 11.9 12.8 15.7 24.7 34.3 52.9 15.3 8.9 20.8 22.1 10.1 107.7 10.9 11.6 97.3 110.6 13.9 16.2 11.3 11.0 11.9 27.8 29.7 16.2 10.3 11.4 14.8 15.9 8.5 18.6 7.6 68.9 15.2 29.9 10.1 11.2 20.3 41.2 30.3 12.1 18.5 14.7 25.2 11.0 18.4 13.4 11.6 52.8 95.4 22.6 85.2 24.1 14.6 50.0 28.6 19.0 33.5 25.2 55.8 36.4 105.0 113.3 17.5 39.3 47.2 61.3 33.3 12.7 48.2 73.4 61.6 59.1 68.9 34.0 51.5 63.5 26.1 21.7 34.5 22.0 12.1 27.2 83.4 62.6 50.7 13.1 96.7 57.6 74.5 24.4 53.6 65.1 55.6 31.7 132.7 60.8 36.6 46.0 28.2 35.5 68.0 67.5 13.2 46.0 40.8 31.7 20.5 20.4 63.9 58.7 24.2 45.0 47.5 25.3 86.4 33.4 4.1 21.0 14.1 11.8 26.6 13.1 14.6 12.8 14.6 31.7 10.3 12.7 12.6 2.4 20.7 24.8 14.7 17.9 12.4 10.5 11.2 11.9 12.8 10.9 11.6 11.3 11.0 11.4 11.2 12.1 11.6 12.6 16.0 20.1 17.0 17.1 8.7 8.2 25.0 9.1 19.3 13.0 8.3 165.4 22.8 21.2 40.5 22.9 58.0 14.2 31.6 92.0 24.9 1.8 36.7 17.3 11.5 9.6 26.3 10.8 20.5 29.0 16.4 27.0 50.4 10.8 33.1 14.3 92.3 38.0 15.2 12.1 24.0 34.6 14.4 7.4 4.9 17.4 16.8 10.6 8.4 16.6 17.2 20.6 8.0 19.6 18.0 18.9 17.3 19.2 7.9 45.6 326.1 21.3 48.1 6.6 11.3 39.3 10.2 32.0 17.1 6.8 39.7 15.8 45.9 37.2 9.8 AIFM3 "AIFL, FLJ30473" ENSG00000183773 "Apoptosis inducing factor mitochondria associated 3" Q96NN9 22 20965108-20981360 "Predicted intracellular proteins" "Apoptosis, Electron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 70.4;choroid plexus: 136.0" "Cell type enhanced" "Detected in many" "Astrocytes: 92.1;Distal enterocytes: 76.5;Intestinal goblet cells: 31.3;Muller glia cells: 25.3;Paneth cells: 27.5;Undifferentiated cells: 37.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 7.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "classical monocyte: 1.1;intermediate monocyte: 3.0;myeloid DC: 1.9;non-classical monocyte: 1.9" "Group enriched" "Detected in many" 24 "dendritic cells: 1.9;monocytes: 3.0" "Cell line enhanced" "Detected in some" "Hep G2: 7.6;HMC-1: 10.8;T-47d: 5.3;THP-1: 7.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001271 Supported Mitochondria NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA001271: AB_1078114" "unprognostic (1.39e-1)" "unprognostic (1.97e-1)" "unprognostic (7.49e-2)" "unprognostic (9.99e-2)" "unprognostic (6.79e-2)" "unprognostic (2.03e-1)" "unprognostic (1.47e-1)" "unprognostic (2.73e-3)" "unprognostic (3.28e-1)" "unprognostic (1.56e-1)" "unprognostic (4.13e-3)" "unprognostic (5.13e-2)" "unprognostic (7.99e-2)" "unprognostic (6.78e-2)" "unprognostic (1.47e-1)" "unprognostic (3.37e-1)" "prognostic favorable (7.13e-5)" 0.5 0.4 41.5 3.1 36.8 3.7 0.4 39.6 52.9 0.3 136.0 24.8 2.5 0.4 0.0 0.4 0.5 0.6 0.3 29.9 31.4 0.8 0.3 1.1 0.6 46.2 43.7 0.3 0.4 0.5 4.4 0.4 43.2 1.0 8.4 1.8 1.0 0.7 0.1 0.1 1.9 0.8 38.0 2.1 0.5 0.6 70.4 0.1 0.3 0.0 0.0 1.2 0.3 24.9 1.0 1.7 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.1 0.0 0.0 1.2 0.1 0.0 0.0 0.2 0.0 1.9 0.0 7.6 0.2 0.0 10.8 0.5 0.6 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 3.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 1.3 0.0 1.3 1.4 0.9 0.8 0.1 0.0 0.1 5.3 7.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 3.0 0.0 0.1 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.5 41.5 36.8 39.6 52.9 29.9 31.4 46.2 43.7 43.2 38.0 70.4 24.9 1.0 0.0 1.5 92.1 1.0 0.6 1.9 1.7 0.6 14.5 3.1 2.4 2.9 0.0 1.4 1.8 6.2 1.0 0.0 76.5 11.7 0.7 0.0 1.7 0.4 0.5 10.3 0.0 12.5 0.6 0.7 0.6 1.5 1.4 1.3 0.5 1.4 2.4 3.6 0.0 8.1 31.3 2.0 3.2 1.9 0.1 0.0 2.5 0.0 4.7 3.2 25.3 0.0 2.5 1.6 0.5 27.5 0.0 0.3 2.2 4.8 8.1 1.9 3.7 0.0 0.2 1.2 0.4 1.9 0.7 0.9 0.8 0.2 0.3 37.9 2.8 AK2 ENSG00000004455 "Adenylate kinase 2" P54819 1 33007940-33080996 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Disease variant, SCID" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 440.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018479, CAB079913" Approved Approved Mitochondria NA NA 1100000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 32: U-937 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "CAB079913: AB_2546087, HPA018479: AB_1844676" "prognostic favorable (4.37e-4)" "unprognostic (3.25e-2)" "unprognostic (2.80e-2)" "prognostic unfavorable (8.65e-4)" "unprognostic (3.16e-2)" "unprognostic (8.21e-2)" "prognostic unfavorable (9.32e-4)" "unprognostic (7.86e-3)" "unprognostic (1.85e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (6.40e-4)" "unprognostic (4.95e-2)" "unprognostic (8.33e-3)" "unprognostic (9.56e-3)" "unprognostic (2.71e-1)" "unprognostic (1.40e-1)" "unprognostic (5.40e-3)" 85.3 88.6 39.9 76.9 45.0 74.3 80.4 44.1 49.0 79.6 49.8 117.2 140.0 58.6 52.1 108.5 65.3 49.0 114.1 38.8 43.8 181.6 172.9 59.3 73.3 48.5 42.8 59.9 78.9 123.6 49.4 68.4 50.4 63.2 114.0 51.0 81.1 55.5 154.2 74.4 139.4 68.1 44.0 57.2 92.7 54.8 44.3 85.9 86.6 122.9 113.4 84.2 76.9 49.3 339.1 153.4 131.6 149.7 94.9 116.6 132.8 185.0 143.5 267.7 280.2 283.2 311.9 602.1 218.4 139.8 204.2 235.4 312.5 327.0 276.6 261.6 229.3 396.2 270.0 219.9 218.2 712.5 222.2 118.1 238.2 232.7 471.2 163.3 190.2 245.7 436.9 230.4 165.0 174.2 273.0 392.8 181.2 337.4 222.4 314.7 222.2 415.6 286.2 205.1 190.8 114.8 205.4 235.0 584.8 151.4 194.5 517.2 138.9 165.5 194.3 259.4 357.5 238.0 324.7 565.7 232.4 664.6 195.5 49.2 158.8 198.0 77.1 145.5 81.8 122.3 72.7 74.0 195.8 105.8 72.9 67.9 42.1 115.3 130.4 154.2 96.8 188.1 39.9 45.0 44.1 49.0 38.8 43.8 48.5 42.8 50.4 44.0 44.3 49.3 60.5 51.3 79.0 19.6 44.0 125.2 101.4 228.1 63.7 21.1 66.5 72.6 106.9 71.4 142.8 112.2 83.4 158.0 37.0 109.6 256.3 120.2 108.3 50.0 42.1 70.7 50.4 50.9 16.2 123.7 164.6 58.0 66.3 47.0 40.0 38.8 41.4 135.5 96.1 8.4 19.7 84.7 89.5 44.8 60.1 42.8 46.9 48.4 87.2 12.2 67.3 22.1 48.4 14.1 22.0 110.5 67.2 44.0 55.7 109.0 236.9 440.0 67.0 41.8 52.6 34.1 108.4 91.0 31.6 88.6 122.7 216.6 40.7 72.2 122.6 120.5 AK3 "AK3L1, AK6, AKL3L1" ENSG00000147853 "Adenylate kinase 3" Q9UIJ7 9 4709556-4742043 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 242.8" "Cell type enhanced" "Detected in all" "Hepatocytes: 305.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 485.4;HEL: 273.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063324 Enhanced Supported Mitochondria NA NA 31000 "Cluster 15: NK-cells - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA063324: AB_2684985" "unprognostic (1.30e-2)" "unprognostic (2.25e-1)" "unprognostic (1.28e-1)" "unprognostic (1.06e-1)" "unprognostic (6.55e-2)" "unprognostic (1.02e-1)" "unprognostic (2.21e-3)" "unprognostic (6.44e-2)" "unprognostic (2.81e-2)" "unprognostic (9.81e-3)" "unprognostic (1.90e-1)" "unprognostic (2.76e-2)" "prognostic favorable (6.07e-9)" "unprognostic (1.24e-1)" "unprognostic (1.40e-1)" "unprognostic (1.39e-1)" "unprognostic (1.55e-3)" 75.5 62.9 30.1 23.7 36.9 20.1 39.7 33.5 34.9 41.0 56.2 67.4 68.3 41.9 31.2 61.2 34.4 35.9 100.6 27.0 40.6 101.4 199.9 34.9 29.6 32.8 38.1 47.8 38.9 66.8 22.2 35.1 33.7 49.2 59.6 16.8 38.7 42.6 242.8 47.4 62.5 41.7 33.5 33.0 69.5 11.2 37.9 35.1 49.9 159.6 34.4 48.7 39.7 36.5 44.1 30.7 55.5 22.6 75.3 55.5 4.9 60.4 116.1 30.4 45.5 5.7 43.6 39.5 20.4 63.5 16.6 29.3 40.8 48.0 51.2 485.4 37.1 273.3 56.1 91.3 58.5 28.7 14.1 87.9 41.4 26.4 36.0 70.4 91.2 38.2 22.1 49.6 91.8 22.5 27.5 65.6 53.3 77.1 15.4 38.2 21.1 19.2 82.1 55.7 98.3 63.6 65.7 18.5 35.1 53.7 26.5 53.2 65.9 25.7 28.8 70.1 43.6 15.5 10.5 50.3 46.9 19.9 18.9 13.3 10.2 32.2 27.6 8.1 25.5 12.1 21.6 25.7 19.6 12.3 28.4 29.2 2.8 27.4 6.5 26.3 31.8 21.1 30.1 36.9 33.5 34.9 27.0 40.6 32.8 38.1 33.7 33.5 37.9 36.5 58.3 57.7 80.3 78.0 34.0 74.2 76.4 87.4 84.2 10.7 58.8 28.3 182.9 68.6 71.0 66.2 22.9 95.5 34.6 129.9 258.2 84.8 3.7 40.7 30.6 65.7 109.6 68.1 23.4 69.6 17.0 83.4 87.1 37.8 46.2 75.8 79.2 305.6 47.5 15.2 55.8 104.2 73.2 46.9 41.4 4.5 108.7 34.7 74.7 22.5 40.9 28.2 33.0 44.7 87.0 67.3 78.7 149.7 62.8 166.7 111.8 183.5 52.8 11.0 105.2 76.0 60.8 6.4 14.1 152.5 104.4 214.0 36.4 68.5 145.5 151.6 AK4 "AK3, AK3L1" ENSG00000162433 "Adenylate kinase 4" P27144 1 65147549-65232145 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 183.5;liver: 104.0" "Cell type enhanced" "Detected in many" "Hepatocytes: 242.6;Proximal tubular cells: 595.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 3.1;myeloid DC: 2.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 208.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042753, HPA049461" Enhanced Supported Mitochondria "Intracellular and membrane" NA Yes 39000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA042753: AB_2678146, HPA049461: AB_2680776" "unprognostic (3.73e-2)" "prognostic unfavorable (4.17e-4)" "unprognostic (2.25e-1)" "unprognostic (3.05e-3)" "unprognostic (1.48e-2)" "prognostic unfavorable (8.83e-4)" "unprognostic (1.16e-3)" "unprognostic (3.89e-2)" "unprognostic (4.03e-1)" "unprognostic (5.39e-2)" "prognostic unfavorable (4.34e-5)" "unprognostic (6.71e-2)" "prognostic unfavorable (4.36e-4)" "prognostic unfavorable (4.87e-4)" "unprognostic (2.69e-1)" "unprognostic (7.07e-2)" "unprognostic (7.57e-2)" 24.7 1.9 19.5 6.6 21.0 4.9 26.6 17.8 20.8 6.1 17.5 19.7 4.3 7.0 4.2 23.4 7.6 13.7 51.7 21.4 21.2 183.5 104.0 2.8 1.6 19.0 22.8 4.6 1.2 18.3 4.7 8.3 22.8 16.2 14.0 21.9 9.6 12.7 1.7 27.4 6.6 21.4 18.5 1.2 15.0 11.3 22.7 5.7 2.5 38.8 3.3 19.1 11.8 21.1 73.2 5.0 5.6 23.9 51.6 48.7 12.0 12.1 15.0 25.6 70.8 108.1 8.6 39.1 31.0 19.0 32.1 46.1 18.8 89.9 101.9 33.0 21.5 37.9 21.9 208.6 2.5 29.9 4.6 27.2 49.6 25.1 73.0 42.2 0.9 12.2 48.0 0.6 39.6 31.2 1.1 1.3 24.6 1.0 42.5 0.2 41.0 7.1 37.8 3.2 20.5 15.4 21.6 1.5 16.7 25.8 29.7 12.9 4.2 42.4 36.2 3.3 20.9 39.5 18.8 2.1 68.7 10.9 2.5 0.9 3.1 0.0 0.1 0.6 0.2 0.2 0.1 0.2 2.7 0.1 0.1 0.1 0.4 0.3 0.1 0.4 0.0 0.8 19.5 21.0 17.8 20.8 21.4 21.2 19.0 22.8 22.8 18.5 22.7 21.1 11.2 0.0 0.5 51.2 4.7 49.7 23.6 44.2 63.7 24.5 48.9 44.7 105.7 52.9 14.3 31.3 2.1 2.2 0.6 15.8 56.7 18.6 3.4 30.1 8.2 19.6 5.4 13.9 17.1 12.1 21.1 11.4 27.5 52.2 0.0 36.4 11.7 242.6 3.3 16.8 7.7 8.7 24.4 7.8 9.2 5.8 4.1 6.9 24.9 3.7 5.7 32.7 0.0 9.5 2.5 31.9 4.3 9.4 0.4 38.7 18.8 595.5 12.3 6.5 6.6 5.6 18.8 1.8 9.5 43.1 74.3 4.9 3.6 0.7 23.1 20.4 AKAP1 "AKAP121, AKAP149, AKAP84, D-AKAP1, PPP1R43, PRKA1, S-AKAP84, SAKAP84, TDRD17" ENSG00000121057 "A-kinase anchoring protein 1" Q92667 17 57085092-57121346 "Predicted intracellular proteins, Predicted membrane proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 207.8" "Group enriched" "Detected in all" 9 "Early spermatids: 584.7;Late spermatids: 2219.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008620, HPA008691, CAB019286" Supported Supported Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "CAB019286: , HPA008620: AB_2668104, HPA008691: AB_1078119" "unprognostic (5.52e-2)" "unprognostic (1.83e-1)" "unprognostic (6.96e-3)" "unprognostic (1.78e-1)" "unprognostic (1.79e-2)" "unprognostic (6.38e-2)" "unprognostic (7.19e-2)" "unprognostic (1.48e-2)" "unprognostic (8.14e-2)" "unprognostic (2.36e-2)" "unprognostic (3.22e-1)" "unprognostic (3.00e-1)" "prognostic favorable (7.86e-9)" "unprognostic (6.82e-2)" "unprognostic (2.46e-1)" "unprognostic (5.74e-2)" "unprognostic (1.38e-1)" 40.6 15.5 31.6 17.8 35.2 6.9 35.2 29.1 35.2 23.7 17.2 76.1 54.8 24.5 19.7 36.4 31.5 18.0 82.6 28.5 26.5 26.2 49.9 19.6 10.8 26.7 27.1 20.0 22.2 48.1 17.1 7.1 26.9 34.7 48.9 34.7 33.6 24.8 207.8 27.3 55.8 26.3 21.9 11.3 55.4 112.9 29.8 11.4 36.3 137.9 9.5 46.8 25.5 28.0 46.1 54.3 80.7 27.5 18.2 12.8 46.8 19.0 18.3 24.2 16.8 61.2 42.2 74.1 52.3 14.5 26.5 74.6 50.1 44.4 24.7 40.6 63.5 63.1 51.4 118.1 19.4 59.9 23.8 11.7 41.8 26.2 39.2 14.4 25.7 22.9 42.3 28.6 14.8 39.8 76.1 24.1 28.7 97.9 61.7 58.2 32.8 61.0 17.1 61.9 58.9 40.3 15.8 45.1 23.9 16.6 31.4 61.4 18.8 24.3 24.2 28.3 45.0 28.9 36.9 55.8 14.0 47.5 19.7 1.6 1.0 0.4 2.6 2.0 2.3 1.8 2.0 2.1 2.3 1.2 4.0 2.1 0.1 3.3 0.5 4.0 1.7 1.3 31.6 35.2 29.1 35.2 28.5 26.5 26.7 27.1 26.9 21.9 29.8 28.0 34.5 35.3 49.9 26.4 16.6 22.6 23.5 11.9 32.5 33.0 29.4 42.3 154.9 28.6 32.1 5.5 47.9 21.5 10.6 89.1 1.9 16.3 584.7 16.8 12.6 16.4 45.9 12.6 14.9 16.3 13.8 12.2 54.0 37.8 3.8 21.0 11.4 60.2 9.5 37.0 26.3 86.6 8.2 9.0 9.5 2219.5 19.6 10.9 7.2 4.7 8.7 8.2 3.1 10.6 9.6 12.7 68.5 13.9 13.2 32.3 65.6 7.4 6.5 77.1 46.0 17.9 54.4 18.3 14.9 44.9 19.7 6.8 11.5 13.3 117.6 17.0 AL021546.1 ENSG00000111780 "Novel protein" 12 120438198-120460006 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "CACO-2: 8.9;HEK 293: 11.5;U-266/84: 10.4" HPA062394 Uncertain Approved Mitochondria NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 11: Alveolar cells - Smell perception" Mitochondria "HPA062394: AB_2684749" "unprognostic (3.79e-2)" "unprognostic (1.74e-1)" "unprognostic (2.79e-1)" "unprognostic (2.90e-1)" "unprognostic (1.71e-1)" "unprognostic (1.33e-1)" "unprognostic (9.54e-4)" "unprognostic (2.04e-1)" 0.0 0.1 0.1 0.0 0.3 0.1 0.0 0.2 0.4 0.1 0.0 0.9 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.2 0.3 0.1 0.0 0.0 0.0 0.4 0.3 0.4 0.4 0.1 0.0 0.1 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.4 0.2 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.0 0.4 2.0 2.6 0.0 0.6 0.0 0.0 0.0 1.8 0.3 0.5 0.0 8.9 0.0 0.5 3.2 0.0 0.8 0.9 0.0 0.5 0.0 1.6 11.5 0.7 0.0 0.0 0.0 4.1 1.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.9 0.2 0.0 0.0 3.2 0.4 0.2 0.0 4.6 1.8 1.2 1.0 0.0 0.0 4.5 0.3 2.9 0.7 0.0 0.0 0.8 0.4 2.4 1.5 0.4 0.0 1.2 0.9 10.4 3.8 0.6 1.3 0.0 1.6 6.1 5.6 5.0 8.9 5.6 4.9 3.0 5.7 11.0 3.8 3.3 3.1 1.3 2.2 6.9 7.9 5.4 4.2 0.1 0.3 0.2 0.4 0.2 0.3 0.4 0.3 0.4 0.2 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ALDH18A1 "GSAS, P5CS, PYCS, SPG9" ENSG00000059573 "Aldehyde dehydrogenase 18 family member A1" P54886 10 95605941-95656711 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Proline biosynthesis" "Kinase, Multifunctional enzyme, Oxidoreductase, Transferase" "Disease variant, Hereditary spastic paraplegia, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 120.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 80.5;Granulosa cells: 81.6;Proximal enterocytes: 79.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008333, HPA012604" Approved Enhanced Mitochondria NA NA 48000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "HPA008333: AB_1078125, HPA012604: AB_1844721" "unprognostic (5.97e-3)" "unprognostic (2.08e-2)" "unprognostic (5.75e-2)" "prognostic favorable (4.20e-4)" "unprognostic (1.60e-2)" "unprognostic (1.06e-1)" "unprognostic (8.30e-3)" "unprognostic (7.08e-2)" "unprognostic (4.06e-2)" "unprognostic (8.04e-2)" "unprognostic (1.30e-1)" "unprognostic (1.81e-1)" "prognostic unfavorable (3.60e-9)" "unprognostic (1.02e-3)" "unprognostic (6.57e-2)" "unprognostic (1.29e-3)" "unprognostic (6.43e-2)" 15.3 16.1 12.2 21.2 12.6 16.7 20.2 12.4 13.1 33.4 21.0 51.9 89.3 18.5 30.9 21.0 21.9 25.2 11.5 12.2 13.6 17.7 24.3 10.8 22.0 12.4 14.7 16.7 61.8 33.5 28.2 26.3 13.1 24.2 49.3 11.4 120.1 24.9 4.3 22.4 73.1 26.3 12.7 12.1 40.5 11.7 14.0 17.2 37.5 5.5 26.9 25.2 14.3 13.1 66.5 61.6 57.9 152.7 76.0 72.9 62.2 75.6 112.8 75.1 93.7 124.4 51.6 223.7 68.9 119.7 36.2 85.6 117.1 77.8 84.6 64.0 92.0 71.2 40.5 177.9 49.7 125.6 76.1 77.0 46.8 61.5 119.1 124.5 79.9 82.6 67.5 46.0 57.1 95.0 114.5 80.5 68.6 109.2 60.7 105.9 66.3 76.9 88.3 49.7 57.5 56.9 60.1 47.1 56.9 66.0 70.5 57.9 66.7 31.1 49.0 80.9 88.2 52.4 41.7 135.8 60.4 142.8 40.7 0.1 2.6 0.2 27.3 5.2 28.7 23.0 24.5 28.3 9.6 16.1 20.7 23.1 0.5 26.3 8.3 5.9 25.8 15.5 12.2 12.6 12.4 13.1 12.2 13.6 12.4 14.7 13.1 12.7 14.0 13.1 4.6 6.4 9.2 7.2 12.6 11.2 8.3 8.9 14.2 6.3 15.6 12.4 4.6 11.5 14.3 20.2 0.0 43.9 6.7 80.5 1.9 13.7 1.3 12.7 18.1 8.0 19.8 17.9 15.7 21.1 31.6 16.2 18.8 16.9 8.2 81.6 5.3 27.3 11.5 10.1 13.6 41.3 8.2 3.5 3.8 1.6 9.3 3.5 16.0 11.2 2.6 7.1 8.2 17.6 12.8 11.7 56.4 12.0 30.1 18.4 79.4 8.4 15.2 3.4 0.0 10.5 10.1 8.2 9.9 17.6 8.1 30.2 9.0 10.8 38.7 9.4 ALDH1L2 "FLJ38508, mtFDH" ENSG00000136010 "Aldehyde dehydrogenase 1 family member L2" Q3SY69 12 105019784-105107643 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "One-carbon metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "pancreas: 40.7;salivary gland: 13.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 23.1;Inhibitory neurons: 24.0;Oligodendrocyte precursor cells: 25.1;Plasma cells: 14.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 62.8;ASC TERT1: 85.2;fHDF/TERT166: 102.4;HHSteC: 55.6;HSkMC: 69.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039481, HPA059282" Approved Enhanced Mitochondria No No "Cluster 25: Pancreas - Digestion" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Mitochondria "HPA039481: AB_10795465, HPA059282: AB_2732633" "unprognostic (5.99e-2)" "unprognostic (1.42e-1)" "unprognostic (1.10e-1)" "unprognostic (1.36e-3)" "unprognostic (1.76e-1)" "unprognostic (8.86e-2)" "unprognostic (1.75e-1)" "unprognostic (2.92e-1)" "unprognostic (5.74e-2)" "unprognostic (1.51e-1)" "unprognostic (1.01e-1)" "unprognostic (1.61e-1)" "unprognostic (8.19e-8)" "unprognostic (3.21e-3)" "unprognostic (1.33e-1)" "unprognostic (2.53e-3)" "unprognostic (2.52e-5)" 3.7 0.6 1.3 3.1 1.2 0.6 2.3 2.3 1.6 5.3 0.7 2.2 2.6 2.0 1.0 1.3 1.5 2.8 1.9 1.1 1.6 0.4 0.2 1.8 1.0 1.4 1.3 0.6 40.7 0.6 1.3 1.1 1.5 3.6 2.3 0.7 13.0 4.6 0.8 1.0 1.4 4.2 1.8 0.7 3.3 1.1 1.6 0.5 2.1 1.2 1.7 3.4 1.5 2.5 13.0 1.3 0.7 27.3 62.8 85.2 1.6 40.8 26.0 5.2 13.5 1.6 0.0 0.0 1.6 102.4 0.2 0.1 0.1 1.0 6.5 0.0 0.3 0.8 0.1 3.4 55.6 5.3 0.1 69.7 3.1 13.6 25.2 0.0 3.0 0.2 2.1 37.7 10.6 0.0 0.0 0.3 1.6 0.0 0.3 0.0 0.1 4.3 0.0 0.0 9.4 4.5 0.0 8.3 20.5 0.4 6.0 44.0 0.3 3.9 3.8 0.0 2.2 45.5 12.8 0.1 16.2 19.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 1.2 2.3 1.6 1.1 1.6 1.4 1.3 1.5 1.8 1.6 2.5 1.4 0.0 0.6 3.3 2.6 0.5 0.1 0.7 0.0 1.7 0.3 1.1 1.6 0.0 0.2 0.0 0.0 0.2 1.5 0.1 0.0 0.3 4.1 0.7 8.5 0.9 0.0 0.0 23.1 9.8 0.6 10.5 1.5 1.6 0.0 0.1 1.1 0.0 0.4 5.0 24.0 0.0 0.0 0.6 1.7 5.9 3.7 1.0 5.4 1.0 4.0 1.3 0.0 25.1 8.5 3.7 0.0 6.8 14.6 0.4 0.0 0.1 0.2 0.8 0.0 3.6 8.4 1.7 0.1 0.0 0.6 0.3 0.9 0.1 0.1 0.2 ALDH4A1 "ALDH4, P5CDh" ENSG00000159423 "Aldehyde dehydrogenase 4 family member A1" P30038 1 18871430-18902724 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Proline metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 200.4;liver: 436.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 78.0;Hepatocytes: 385.1;Proximal tubular cells: 279.4;Syncytiotrophoblasts: 86.6" "Cancer enhanced" "Detected in all" "liver cancer: 72.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Hep G2: 83.7;SK-BR-3: 85.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004645, HPA006401, HPA072759" Enhanced Supported Mitochondria NA NA 58000 "Cluster 7: Monocytes - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "CAB004645: AB_425775, HPA006401: AB_1844731, HPA072759: " "unprognostic (1.17e-1)" "prognostic favorable (5.06e-4)" "unprognostic (1.38e-2)" "unprognostic (4.16e-2)" "unprognostic (3.15e-1)" "unprognostic (7.67e-2)" "unprognostic (1.28e-1)" "unprognostic (6.18e-2)" "unprognostic (1.92e-1)" "unprognostic (1.09e-2)" "unprognostic (1.02e-1)" "unprognostic (2.06e-1)" "unprognostic (4.27e-3)" "unprognostic (9.41e-3)" "unprognostic (3.83e-1)" "unprognostic (2.69e-3)" "unprognostic (9.34e-2)" 70.8 16.1 73.9 3.9 88.9 11.7 21.6 73.8 95.9 12.6 106.5 6.8 1.6 9.8 4.7 36.3 8.3 5.5 33.0 68.2 73.8 200.4 436.6 6.2 3.4 72.9 82.8 7.3 4.6 23.0 9.7 13.2 70.0 29.5 2.7 6.5 9.1 27.1 74.2 19.2 4.7 7.1 65.6 7.5 12.5 3.2 92.4 11.7 7.1 74.8 4.2 19.3 16.8 66.1 12.7 17.8 9.5 29.2 40.0 5.7 25.2 13.1 7.1 11.8 9.5 13.7 8.9 8.8 16.6 15.6 5.7 34.0 16.7 35.4 4.5 4.8 15.9 5.9 5.0 83.7 12.6 4.4 15.1 15.6 19.2 6.5 6.6 9.0 13.5 14.0 21.0 5.7 8.1 32.3 4.3 20.2 4.7 26.0 10.1 27.9 8.4 10.0 12.1 32.0 19.6 7.6 21.9 85.0 16.1 14.7 38.7 6.3 11.3 10.2 14.0 12.2 4.5 7.1 17.9 2.5 3.4 33.7 13.5 0.0 2.7 1.5 0.6 3.6 0.5 0.8 0.3 0.8 4.4 0.7 0.2 0.5 0.3 0.1 2.0 1.5 0.6 1.5 73.9 88.9 73.8 95.9 68.2 73.8 72.9 82.8 70.0 65.6 92.4 66.1 2.6 0.0 2.8 27.1 4.3 7.5 17.9 12.5 17.6 3.7 9.8 8.5 20.9 34.3 2.9 46.0 10.4 78.0 2.0 2.0 46.9 6.5 0.5 1.1 1.7 3.1 2.4 32.2 1.2 0.9 12.6 3.2 7.7 3.9 4.5 2.1 15.4 385.1 13.8 20.2 1.6 3.6 6.1 17.2 1.4 0.6 1.2 4.7 3.6 1.9 10.9 14.0 1.0 5.5 1.3 2.5 1.8 2.6 4.4 12.0 0.3 279.4 1.7 4.8 6.6 2.6 4.7 2.2 3.9 21.7 5.4 86.6 2.6 4.5 4.0 9.5 ALDH5A1 "SSADH, SSDH" ENSG00000112294 "Aldehyde dehydrogenase 5 family member A1" P51649 6 24494867-24537207 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 98.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 90.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 136.6;U-698: 173.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029715, HPA029716" Enhanced Supported Mitochondria NA NA 50000 "Cluster 30: Non-specific - Translation" "Cluster 39: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA029715: AB_10599994, HPA029716: AB_10601876" "unprognostic (7.43e-2)" "unprognostic (1.12e-3)" "unprognostic (1.80e-1)" "unprognostic (1.22e-1)" "unprognostic (2.23e-1)" "unprognostic (3.27e-1)" "prognostic favorable (7.61e-6)" "unprognostic (2.38e-2)" "unprognostic (2.17e-2)" "prognostic favorable (6.20e-4)" "unprognostic (1.43e-2)" "unprognostic (1.21e-1)" "prognostic favorable (3.68e-4)" "unprognostic (1.04e-2)" "unprognostic (1.16e-1)" "unprognostic (2.00e-2)" "unprognostic (1.08e-2)" 9.4 6.1 27.8 5.9 28.9 4.4 5.2 25.0 32.7 5.4 18.8 8.5 11.8 4.8 3.7 7.3 19.0 5.1 14.5 26.5 32.8 27.8 98.8 6.4 13.6 26.7 35.0 7.3 8.2 19.4 5.8 2.4 27.3 8.2 7.1 11.0 5.2 5.2 57.9 9.5 8.0 3.1 29.4 6.8 7.7 4.5 34.0 26.8 17.0 33.8 12.9 6.7 8.4 24.9 11.5 9.3 6.5 10.1 0.1 0.0 11.7 0.8 2.0 2.4 1.6 35.1 2.5 136.6 21.1 1.0 2.2 0.1 10.5 1.3 1.5 14.7 20.2 20.7 5.9 42.4 1.6 32.2 2.7 1.0 4.4 0.2 0.0 7.1 0.1 34.7 10.4 0.0 1.8 23.3 40.4 19.0 2.7 18.4 5.5 46.1 1.4 1.3 7.7 19.6 11.7 10.5 12.1 1.2 13.2 2.8 19.4 17.5 0.2 1.1 6.7 0.3 7.1 19.4 32.2 173.7 0.2 9.8 1.4 0.3 0.0 0.1 1.0 0.0 1.9 2.2 1.4 1.5 0.1 2.0 3.8 3.4 0.2 0.8 0.1 2.4 0.9 0.7 27.8 28.9 25.0 32.7 26.5 32.8 26.7 35.0 27.3 29.4 34.0 24.9 2.9 16.0 25.3 14.0 9.7 1.7 5.6 8.2 2.2 12.9 7.5 3.4 34.8 11.5 9.4 7.3 16.7 6.1 7.4 6.1 1.9 1.6 0.8 15.2 5.0 3.7 8.4 16.0 18.1 1.0 5.2 3.5 5.6 5.4 7.0 13.5 6.8 90.7 3.9 16.8 32.4 11.7 2.0 3.8 1.8 0.3 3.4 1.7 1.8 8.4 0.2 11.8 3.1 11.6 2.4 1.3 7.7 4.5 12.2 4.1 13.4 26.8 12.8 6.9 0.0 6.9 2.3 1.7 6.6 8.7 3.0 1.9 5.4 8.0 17.0 13.1 ALDH6A1 MMSDH ENSG00000119711 "Aldehyde dehydrogenase 6 family member A1" Q02252 14 74056847-74084492 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "kidney: 379.1;liver: 367.1" "Cell type enhanced" "Detected in all" "Distal tubular cells: 201.5;Hepatocytes: 523.6;Proximal tubular cells: 962.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 43.2" "Lineage enriched" "Detected in all" 4 "granulocytes: 43.2" "Cell line enhanced" "Detected in all" "T-47d: 57.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029072, HPA029073, HPA029074, HPA029075" Enhanced Enhanced Mitochondria No No 37000 "Cluster 2: Granulocytes - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA029072: AB_10599176, HPA029073: AB_10601877, HPA029074: AB_10601000, HPA029075: AB_10602005" "unprognostic (1.45e-1)" "unprognostic (5.38e-2)" "unprognostic (6.89e-2)" "unprognostic (6.95e-3)" "unprognostic (1.46e-1)" "unprognostic (7.93e-2)" "unprognostic (1.11e-3)" "prognostic favorable (4.22e-4)" "unprognostic (1.58e-1)" "unprognostic (9.10e-2)" "unprognostic (3.11e-2)" "unprognostic (2.13e-1)" "prognostic favorable (2.00e-15)" "unprognostic (4.59e-1)" "unprognostic (1.92e-1)" "unprognostic (6.05e-3)" "unprognostic (1.12e-1)" 38.7 14.7 58.6 4.8 66.0 3.3 14.4 58.8 59.3 17.3 61.4 15.2 26.6 11.4 9.8 9.8 12.8 9.4 40.3 51.0 54.0 379.1 367.1 9.4 5.1 63.3 54.0 28.3 23.4 37.0 6.6 7.6 55.6 25.4 15.8 15.2 19.8 16.1 27.5 6.2 23.4 9.0 56.4 5.4 24.0 17.1 69.8 5.7 28.3 34.8 5.3 11.4 7.0 62.6 8.9 7.8 11.0 23.5 39.3 19.2 17.5 6.3 11.8 6.8 11.5 17.3 10.2 10.5 13.6 13.5 5.3 4.8 24.9 7.0 14.5 9.5 3.5 5.1 8.0 19.2 45.0 2.7 2.4 28.2 12.0 8.7 20.7 17.0 12.0 23.7 8.1 14.7 4.6 36.2 7.6 4.0 8.7 32.6 5.2 15.1 11.2 14.6 9.2 5.8 4.4 7.0 21.0 21.9 5.7 18.0 57.5 9.6 3.8 7.4 9.0 11.7 2.4 9.3 18.9 10.2 9.9 3.2 7.3 29.1 6.2 43.2 6.9 4.8 10.6 7.2 7.8 8.4 9.2 6.1 9.9 7.0 2.4 9.7 4.2 5.3 6.1 4.9 58.6 66.0 58.8 59.3 51.0 54.0 63.3 54.0 55.6 56.4 69.8 62.6 15.4 38.5 60.4 24.5 11.8 9.2 26.8 10.0 20.5 20.6 28.4 18.9 81.4 67.2 22.9 66.2 4.2 31.0 7.1 18.9 201.5 11.6 23.4 26.2 27.5 27.0 16.9 28.6 5.5 3.1 14.8 25.9 34.7 90.2 7.6 27.1 87.4 523.6 17.7 11.8 10.0 39.3 8.2 26.5 8.9 19.0 28.9 13.4 24.9 1.9 15.8 98.5 9.2 12.5 23.4 4.1 16.3 48.2 8.0 27.6 55.3 962.4 15.4 17.0 13.1 25.6 16.9 11.0 4.2 25.2 7.4 30.6 11.0 10.2 35.7 17.2 ALKBH7 "MGC10974, SPATA11" ENSG00000125652 "AlkB homolog 7" Q9BT30 19 6372794-6375250 "Predicted intracellular proteins" Necrosis "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 517.8" "Group enriched" "Detected in all" 4 "Early spermatids: 3004.6;Late spermatids: 8717.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008539, HPA039571, HPA039872" Approved Supported Mitochondria NA NA "Cluster 30: Non-specific - Translation" "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "HPA008539: , HPA039571: AB_2676577, HPA039872: AB_10697710" "unprognostic (5.38e-2)" "unprognostic (3.58e-2)" "unprognostic (2.20e-1)" "unprognostic (1.15e-2)" "unprognostic (7.79e-2)" "unprognostic (3.56e-3)" "unprognostic (1.06e-1)" "unprognostic (1.35e-1)" "unprognostic (3.02e-1)" "unprognostic (6.83e-2)" "unprognostic (1.72e-3)" "unprognostic (1.54e-1)" "prognostic favorable (7.83e-6)" "unprognostic (7.07e-2)" "unprognostic (2.00e-1)" "unprognostic (2.57e-1)" "unprognostic (1.10e-2)" 48.9 64.5 59.8 19.2 62.3 31.1 51.3 65.7 74.2 54.6 69.5 72.5 65.8 48.4 14.6 66.1 55.4 19.2 157.2 56.6 61.3 86.0 152.9 40.4 26.9 64.0 61.3 68.8 112.3 44.9 67.5 14.3 61.0 70.1 20.0 15.8 65.2 30.5 154.4 61.0 61.5 12.8 63.6 46.6 68.4 517.8 61.6 28.1 73.0 67.4 15.9 52.1 51.6 68.5 28.9 25.2 21.4 37.1 11.8 32.7 30.9 20.5 18.0 18.1 19.1 44.0 18.3 42.1 68.4 26.2 12.8 22.1 9.6 17.1 3.5 40.9 38.9 24.5 17.6 41.4 34.5 12.4 31.3 37.6 33.8 15.7 12.3 17.5 22.5 40.7 26.2 80.0 13.9 58.3 63.5 42.6 30.8 33.9 106.1 46.6 13.4 84.2 20.4 22.1 30.3 46.3 13.8 36.1 76.4 10.1 41.0 44.7 20.3 18.0 25.0 66.9 20.1 129.2 98.1 27.7 33.9 41.9 15.9 38.3 106.4 17.3 52.7 91.6 72.9 113.4 91.4 72.5 127.6 103.0 137.4 111.1 64.4 66.1 72.0 143.9 85.7 91.5 59.8 62.3 65.7 74.2 56.6 61.3 64.0 61.3 61.0 63.6 61.6 68.5 84.8 60.9 74.4 3.3 109.0 83.7 154.4 129.1 160.5 93.1 221.6 335.4 106.3 112.9 83.9 66.2 66.7 97.6 79.3 516.1 313.1 110.1 3004.6 76.1 73.0 84.8 220.4 54.0 2.4 245.2 149.6 88.0 77.5 85.1 66.0 108.3 113.2 302.0 196.8 42.1 3.5 400.4 71.2 168.6 96.2 8717.7 103.2 128.6 133.4 1.9 192.6 166.1 69.0 3.0 9.3 116.0 528.2 88.8 121.0 121.1 856.4 433.6 52.7 152.4 92.1 97.2 104.1 1180.3 76.7 171.2 100.6 108.9 87.4 143.4 410.5 215.6 ANKRD33B ENSG00000164236 "Ankyrin repeat domain 33B" A6NCL7 5 10564070-10657816 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.5;retina: 50.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 350.3;Excitatory neurons: 110.4;Rod photoreceptor cells: 73.4" "Cancer enhanced" "Detected in many" "renal cancer: 7.4" "Region enhanced" "Detected in many" "hippocampal formation: 20.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 23.7;HDLM-2: 47.0;HMC-1: 29.8" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "amygdala: 7.7;basal ganglia: 16.2;cerebral cortex: 19.6;hippocampal formation: 16.0;olfactory bulb: 10.0" HPA056974 Uncertain Approved Mitochondria NA NA "Cluster 58: Brain - Synaptic function" "Cluster 44: HDLM-2 - Immune response" "Cluster 9: Photoreceptor cells - Phototransduction" Mitochondria "HPA056974: AB_2683295" "unprognostic (6.19e-2)" "unprognostic (2.61e-1)" "unprognostic (1.09e-2)" "unprognostic (5.65e-3)" "unprognostic (2.84e-2)" "unprognostic (1.21e-1)" "unprognostic (1.99e-1)" "unprognostic (4.50e-3)" "unprognostic (4.41e-1)" "unprognostic (2.42e-3)" "unprognostic (1.14e-1)" "unprognostic (1.00e-1)" "prognostic favorable (4.16e-5)" "unprognostic (1.17e-1)" "unprognostic (4.80e-2)" "unprognostic (2.39e-2)" "unprognostic (5.47e-2)" 2.7 0.1 5.0 2.2 6.3 9.1 1.7 0.0 12.9 2.2 0.1 2.1 0.4 4.9 0.5 1.9 3.4 0.9 4.3 20.5 0.0 5.9 0.4 1.7 3.5 0.0 0.1 0.4 1.5 0.3 0.5 2.1 0.0 1.8 1.0 50.8 0.8 2.4 4.4 6.9 2.4 3.8 0.0 7.2 1.7 1.0 0.5 7.0 0.4 8.4 4.4 3.0 3.2 4.3 4.3 6.3 0.4 0.5 14.3 6.7 18.5 1.2 2.1 2.5 2.9 7.8 3.4 23.7 20.7 4.0 3.0 4.3 2.1 2.1 2.8 47.0 1.4 9.3 5.7 0.0 6.5 7.1 29.8 3.3 1.6 1.3 8.3 0.6 3.1 1.7 2.1 11.1 0.6 0.0 0.3 8.6 4.9 0.0 1.9 1.9 4.7 0.8 8.3 3.0 0.1 0.2 0.1 0.4 0.7 15.5 0.0 8.8 9.0 1.4 9.0 7.5 2.3 12.9 15.3 2.0 0.4 11.3 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 6.3 0.0 12.9 20.5 0.0 0.0 0.1 0.0 0.0 0.5 4.3 1.6 12.8 1.5 9.8 14.4 0.4 2.5 0.0 2.2 26.5 0.6 0.4 5.6 4.3 0.6 3.7 350.3 1.6 0.7 0.0 1.9 1.7 6.5 14.2 20.7 2.4 0.0 2.1 110.4 0.2 0.8 8.6 0.5 24.2 0.0 0.0 3.3 0.0 0.2 6.7 24.5 0.0 0.0 0.0 0.8 0.6 1.5 4.3 1.8 6.5 15.4 10.2 0.0 5.5 1.5 0.2 0.0 0.0 30.8 7.3 0.0 18.4 0.0 73.4 0.0 7.8 6.0 0.1 3.3 6.3 1.1 0.5 2.9 2.8 0.0 2.0 ANKRD34C ENSG00000235711 "Ankyrin repeat domain 34C" P0C6C1 15 79293285-79298235 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 7 "brain: 5.5" "Group enriched" "Detected in some" 4 "Excitatory neurons: 3.0;Inhibitory neurons: 1.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 17 "SCLC-21H: 8.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA045329 Approved Mitochondria NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Mitochondria "HPA045329: AB_2679291" "unprognostic (3.20e-1)" "unprognostic (1.08e-1)" "unprognostic (1.52e-2)" "unprognostic (1.81e-1)" "unprognostic (3.42e-3)" "unprognostic (5.31e-2)" "unprognostic (2.48e-1)" 0.1 0.1 1.4 0.0 0.5 0.0 0.0 2.0 1.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 3.0 0.0 0.0 0.1 0.0 2.2 2.8 0.0 0.2 0.0 0.7 0.0 3.4 0.0 0.0 0.5 0.0 0.0 0.1 0.7 0.0 0.0 0.2 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.5 2.0 1.9 0.4 3.0 2.2 2.8 3.4 0.2 5.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ANKRD63 ENSG00000230778 "Ankyrin repeat domain 63" C9JTQ0 15 40281444-40282586 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 81 "brain: 20.9" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "basal ganglia: 20.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.9;THP-1: 1.4" "Region enhanced" "Detected in many" "basal ganglia: 56.7" HPA066743 Approved Mitochondria NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 43: Cardiomyocytes - Nuclear processes" Mitochondria "HPA066743: " "unprognostic (9.36e-2)" "unprognostic (7.45e-2)" "unprognostic (8.32e-2)" "unprognostic (4.42e-1)" 0.0 0.0 3.6 0.0 20.9 0.0 0.0 0.0 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 1.3 2.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.9 0.9 0.4 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.5 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 20.9 0.0 10.6 1.3 2.1 0.0 0.3 0.0 0.0 4.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AP001267.5 ENSG00000285827 "Novel protein" 11 118401602-118482737 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 7.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 16.0;Alveolar cells type 2: 24.1;Club cells: 14.9;granulocytes: 20.2;Respiratory ciliated cells: 13.8" "Region enhanced" "Detected in many" "cerebellum: 3.8" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA044629 Uncertain Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 2: Karpas-707 - Immune response" "Cluster 11: Alveolar cells - Smell perception" Mitochondria "HPA044629: AB_2679028" 1.2 1.2 0.7 1.5 0.9 7.2 1.3 3.8 1.3 0.8 0.4 1.3 1.8 0.8 1.1 0.6 0.8 0.7 1.2 0.7 1.4 1.2 1.2 0.9 2.4 0.2 0.1 0.8 0.8 1.6 0.7 0.2 1.4 1.2 1.5 1.4 0.8 1.5 0.5 1.8 0.8 0.0 1.0 1.4 0.7 0.2 2.6 1.1 1.8 1.3 1.0 1.6 3.1 0.7 2.0 2.7 0.9 0.8 3.8 1.5 1.2 1.9 1.9 3.3 2.5 2.6 3.6 1.9 4.0 2.4 2.8 2.4 2.8 4.0 1.8 4.3 1.2 1.6 1.8 2.9 3.0 1.4 1.3 2.3 3.0 1.2 2.4 6.1 3.4 6.7 1.7 2.4 4.5 5.7 1.7 5.5 2.6 3.9 2.2 3.4 3.4 1.2 3.3 2.3 2.4 1.2 1.5 3.0 1.9 1.5 1.3 2.0 4.2 1.1 1.9 1.7 1.6 5.2 0.7 3.1 1.0 5.5 5.1 6.0 4.9 4.2 4.1 6.1 4.4 4.0 5.0 5.1 4.2 4.0 4.1 3.7 4.0 7.2 5.8 10.6 0.7 0.9 3.8 1.3 0.7 1.4 0.2 0.1 0.2 0.0 0.2 1.6 0.0 16.0 24.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 20.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 APBB2 "FE65L, FE65L1, MGC35575" ENSG00000163697 "Amyloid beta precursor protein binding family B member 2" Q92870 4 40810027-41216714 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 72.9" "Group enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 586.1;Oligodendrocytes: 803.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 14 "naive B-cell: 5.6" "Lineage enriched" "Detected in single" 14 "B-cells: 5.6" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 138.7;TIME: 192.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023542 Approved Approved Mitochondria No No "Cluster 21: B-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA023542: AB_1844909" "unprognostic (4.43e-2)" "unprognostic (4.40e-2)" "unprognostic (2.04e-2)" "prognostic unfavorable (1.97e-4)" "unprognostic (5.91e-3)" "unprognostic (8.13e-2)" "unprognostic (5.77e-2)" "unprognostic (4.00e-3)" "unprognostic (2.51e-1)" "unprognostic (1.21e-2)" "unprognostic (1.61e-1)" "unprognostic (1.33e-1)" "unprognostic (2.19e-3)" "unprognostic (9.35e-3)" "unprognostic (3.92e-2)" "unprognostic (2.29e-2)" "unprognostic (2.61e-1)" 41.6 9.1 23.1 5.4 42.3 8.6 25.1 38.1 24.5 16.1 3.7 13.9 8.3 14.0 5.9 8.9 13.1 16.1 21.5 20.6 30.6 16.5 14.7 18.6 7.4 42.9 39.6 32.1 10.8 8.5 8.5 17.6 39.5 8.7 7.7 15.7 8.6 9.8 28.7 12.6 7.0 14.9 25.2 14.8 11.3 8.5 36.7 13.2 33.6 21.7 5.6 10.7 13.1 72.9 19.4 9.4 20.6 28.8 64.9 50.7 45.2 38.5 45.8 14.0 24.5 34.1 40.2 33.9 20.7 16.5 44.5 5.6 36.5 49.4 25.0 1.1 7.3 0.4 23.5 21.1 65.0 19.2 1.1 76.7 24.6 42.5 43.0 58.2 138.7 19.0 1.1 0.7 86.1 16.3 6.3 3.6 17.1 9.8 17.9 50.9 58.6 38.4 19.9 8.9 27.2 15.4 11.7 6.6 6.9 23.7 17.2 2.2 192.3 20.1 59.5 13.8 61.1 8.1 18.5 41.2 20.7 30.8 24.6 0.4 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 5.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 23.1 42.3 38.1 24.5 20.6 30.6 42.9 39.6 39.5 25.2 36.7 72.9 58.8 80.1 14.5 46.7 5.0 10.7 3.8 10.4 7.4 7.6 25.5 13.6 22.5 12.8 6.3 9.2 6.2 14.4 0.5 5.2 7.9 3.8 14.5 5.6 32.8 39.4 3.0 5.3 121.3 6.4 2.8 25.2 12.8 7.5 1.3 13.5 47.2 13.8 3.2 62.2 171.3 4.0 16.2 4.0 6.7 23.1 35.8 2.5 7.2 164.9 0.1 9.3 0.0 586.1 803.4 6.2 6.7 37.2 0.2 2.7 5.5 6.3 4.0 7.6 59.2 43.2 51.4 3.8 10.8 7.3 11.9 6.0 1.2 24.0 7.4 3.6 APCDD1L FLJ90166 ENSG00000198768 "APC down-regulated 1 like" Q8NCL9 20 58459101-58515399 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "salivary gland: 19.2" "Cell type enhanced" "Detected in some" "Breast glandular cells: 9.1;Breast myoepithelial cells: 7.7;Fibroblasts: 3.6;Oligodendrocyte precursor cells: 6.0;Skeletal myocytes: 8.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 94.5;hTEC/SVTERT24-B: 32.7;HUVEC TERT2: 33.6;TIME: 56.1;U-87 MG: 36.5" "Not detected" "Not detected" HPA067015 Uncertain Uncertain Mitochondria No No "Cluster 24: Salivary gland - Salivary secretion" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Mitochondria "HPA067015: AB_2685764" "unprognostic (2.61e-1)" "unprognostic (8.26e-3)" "unprognostic (4.63e-3)" "unprognostic (1.35e-5)" "unprognostic (4.09e-3)" "unprognostic (9.73e-3)" "unprognostic (1.31e-3)" "unprognostic (1.06e-4)" "unprognostic (7.63e-4)" "unprognostic (2.14e-2)" "unprognostic (7.62e-3)" "unprognostic (2.16e-1)" "unprognostic (6.55e-13)" "unprognostic (5.01e-3)" "unprognostic (3.21e-1)" "unprognostic (2.24e-2)" "unprognostic (1.81e-3)" 0.4 0.4 0.2 0.2 0.0 0.0 4.8 0.5 0.1 1.7 0.0 1.0 0.1 1.8 0.0 0.5 0.0 0.7 1.4 0.1 0.0 2.9 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.4 0.1 0.0 0.5 0.6 0.0 19.2 1.3 0.6 0.8 0.4 0.6 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 4.4 0.6 0.0 0.0 0.0 0.0 0.0 0.4 3.1 0.0 16.8 0.1 1.9 1.4 0.0 5.6 0.0 0.0 94.5 0.5 1.1 0.0 3.3 3.3 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 2.6 0.0 32.7 0.5 6.8 33.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 56.1 12.6 0.9 0.0 16.5 0.0 0.0 0.0 36.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 2.0 0.1 0.0 0.3 0.4 0.0 0.0 9.1 7.7 0.9 0.0 0.0 1.8 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.0 0.0 0.7 0.0 0.0 3.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 6.0 0.5 0.8 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 8.4 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 APOOL "AAIR8193, CXorf33, FAM121A, Mic27, MICOS27, UNQ8193" ENSG00000155008 "Apolipoprotein O like" Q6UXV4 X 85003877-85093316 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000612 Approved Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA000612: AB_1078594" "prognostic unfavorable (2.68e-5)" "unprognostic (2.72e-2)" "unprognostic (6.16e-2)" "unprognostic (5.71e-3)" "unprognostic (4.27e-3)" "unprognostic (1.47e-1)" "unprognostic (2.73e-1)" "unprognostic (2.22e-2)" "unprognostic (8.35e-2)" "unprognostic (1.10e-1)" "unprognostic (2.77e-1)" "unprognostic (8.20e-2)" "prognostic favorable (1.35e-12)" "unprognostic (2.67e-2)" "unprognostic (5.65e-2)" "unprognostic (7.11e-2)" "unprognostic (7.51e-2)" 5.9 6.5 2.8 3.7 3.2 3.7 6.6 3.6 5.2 4.3 5.4 5.9 5.9 4.4 4.7 6.2 5.1 4.0 11.5 4.2 3.9 11.2 14.5 4.3 3.3 4.5 4.3 4.1 6.0 11.6 3.2 4.1 4.6 5.9 6.5 6.8 5.8 4.4 17.8 6.7 4.6 5.9 2.9 3.5 6.8 2.2 4.6 3.6 8.3 17.9 3.5 4.2 4.0 4.3 11.4 6.5 6.0 8.2 16.9 11.7 6.4 7.4 6.9 6.2 6.0 7.0 6.3 8.3 6.9 8.4 11.7 8.8 18.3 7.0 9.3 8.4 8.0 8.8 10.2 7.2 11.0 17.5 9.1 11.8 11.8 10.4 18.4 7.2 8.8 10.7 15.2 10.7 10.8 6.1 7.2 7.1 4.9 6.8 12.1 7.9 14.6 8.6 7.8 8.3 0.6 9.8 14.1 12.7 8.8 6.4 7.7 8.3 9.2 8.5 8.3 17.5 8.6 6.9 24.4 7.1 10.9 12.4 7.3 2.4 2.0 0.6 1.9 2.8 1.7 2.1 1.7 1.4 2.1 1.9 2.1 2.0 0.4 1.2 2.5 2.6 1.0 1.0 2.8 3.2 3.6 5.2 4.2 3.9 4.5 4.3 4.6 2.9 4.6 4.3 16.7 16.0 19.1 25.8 10.7 5.6 13.3 5.3 6.2 26.7 16.8 11.9 45.4 15.7 7.7 20.2 14.6 15.3 9.3 10.6 13.7 18.1 0.2 17.0 15.4 13.0 37.1 14.9 32.3 14.0 11.3 13.9 17.3 17.4 21.5 18.3 15.0 51.6 12.0 21.9 26.2 15.3 4.1 15.2 2.3 0.8 13.7 11.4 0.0 21.5 9.5 13.6 8.2 30.2 36.2 17.5 14.6 15.4 8.7 19.6 15.6 43.7 7.6 16.8 19.7 19.3 16.9 3.1 8.2 11.5 3.4 19.4 6.6 16.8 15.4 17.8 AREG "AREGB, SDGF" ENSG00000109321 Amphiregulin P15514 4 74445136-74455005 "Cancer-related genes, Human disease related genes, Predicted membrane proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 129.9;placenta: 328.8;urinary bladder: 145.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1119.1;Basal prostatic cells: 1254.3;Macrophages: 1271.1;Paneth cells: 909.8;Urothelial cells: 2102.9" "Cancer enhanced" "Detected in all" "colorectal cancer: 67.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "basophil: 11.0;eosinophil: 11.8;NK-cell: 3.8" "Group enriched" "Detected in many" 10 "granulocytes: 11.8;NK-cells: 3.8" "Cell line enhanced" "Detected in many" "CACO-2: 379.0;HBEC3-KT: 648.1;hTCEpi: 644.0;hTERT-HME1: 1365.7;MCF7: 416.8" "Region enriched" "Detected in single" 4 "olfactory bulb: 1.2" "Low region specificity" "Detected in many" "HPA008720, CAB023519" Approved Approved Mitochondria NA NA 1520000 "Cluster 2: Granulocytes - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" Mitochondria "CAB023519: AB_2060673, HPA008720: AB_1844978" "unprognostic (1.44e-2)" "unprognostic (1.84e-3)" "unprognostic (3.36e-2)" "unprognostic (2.26e-1)" "unprognostic (3.54e-3)" "prognostic unfavorable (2.61e-5)" "unprognostic (1.02e-2)" "prognostic unfavorable (1.05e-5)" "unprognostic (2.90e-1)" "unprognostic (8.06e-2)" "prognostic unfavorable (8.32e-5)" "unprognostic (2.56e-2)" "unprognostic (2.49e-3)" "unprognostic (2.40e-2)" "unprognostic (1.69e-1)" "unprognostic (1.23e-1)" "unprognostic (6.83e-3)" 48.1 4.6 0.1 36.7 0.1 129.9 61.6 0.1 0.8 19.2 1.8 18.7 3.3 3.7 0.2 43.4 13.2 74.1 20.5 0.3 0.1 2.5 4.0 36.1 1.9 0.3 0.2 12.4 4.5 1.5 9.5 328.8 0.8 6.5 18.9 0.1 11.7 0.7 18.4 15.3 10.2 6.5 0.2 10.0 20.2 9.3 0.4 7.1 5.4 0.8 3.0 145.6 13.8 0.4 15.9 107.3 0.0 0.0 0.9 1.4 0.0 3.2 5.0 0.7 2.9 379.0 59.8 0.0 8.0 0.0 0.0 17.4 0.1 648.1 6.5 0.1 0.0 0.4 2.8 18.0 191.9 2.3 0.4 5.9 644.0 37.8 1365.7 0.9 0.2 0.4 1.6 0.7 14.4 416.8 0.2 0.0 0.0 78.6 42.8 0.0 0.1 0.1 36.4 2.9 0.5 0.2 22.2 1.2 0.0 0.4 11.6 0.1 1.0 0.0 15.3 5.3 0.1 0.9 0.0 0.1 0.0 0.0 1.7 11.0 0.0 11.8 0.0 0.0 0.0 0.2 0.4 0.0 0.8 0.3 0.2 0.0 0.1 3.8 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.8 0.3 0.1 0.3 0.2 0.8 0.2 0.4 0.4 670.0 198.7 301.9 0.0 190.7 1119.1 1254.3 73.0 303.9 0.0 801.5 460.2 49.0 62.9 183.9 51.5 0.0 1.8 836.1 878.0 0.0 61.8 70.4 167.7 12.3 32.2 41.6 18.5 0.0 10.2 1.5 80.8 254.9 193.1 680.5 0.9 10.8 4.2 32.2 0.0 0.5 393.5 8.2 250.4 196.4 12.1 0.3 1271.1 33.8 0.0 1.7 0.8 20.6 0.0 0.0 497.1 909.8 1.2 352.1 115.3 55.7 0.7 53.3 0.2 19.7 10.3 20.2 68.3 51.1 194.5 342.4 1.1 473.6 1.2 308.9 2102.9 ARG2 ENSG00000081181 "Arginase 2" P78540 14 67619920-67651708 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Adaptive immunity, Arginine metabolism, Immunity, Innate immunity, Urea cycle" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 220.0;prostate: 108.5;thyroid gland: 105.0" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 190.1;Collecting duct cells: 165.5;Glandular and luminal cells: 145.2;Proximal tubular cells: 220.9;Syncytiotrophoblasts: 601.3;Urothelial cells: 165.2" "Cancer enhanced" "Detected in all" "prostate cancer: 49.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 58.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000663, CAB009435" Enhanced Supported Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Mitochondria "CAB009435: AB_2059089, HPA000663: AB_1078192" "unprognostic (8.74e-3)" "unprognostic (3.06e-2)" "unprognostic (1.35e-2)" "unprognostic (2.29e-1)" "unprognostic (2.30e-1)" "unprognostic (9.13e-2)" "unprognostic (1.10e-2)" "unprognostic (3.43e-3)" "unprognostic (4.62e-3)" "unprognostic (5.37e-2)" "unprognostic (4.66e-3)" "unprognostic (1.72e-1)" "unprognostic (9.39e-2)" "unprognostic (4.26e-1)" "unprognostic (2.31e-1)" "unprognostic (4.34e-1)" "unprognostic (1.26e-1)" 2.8 7.3 5.6 2.9 6.1 0.5 4.8 6.9 13.9 17.0 7.9 2.7 3.7 7.0 3.6 16.3 1.8 9.3 3.4 6.3 11.6 64.0 3.8 3.8 0.5 6.4 7.7 18.7 5.0 220.0 45.6 8.8 9.2 108.5 1.4 22.3 17.0 5.8 35.7 2.1 15.3 3.7 5.1 0.9 3.2 3.4 6.5 3.0 105.0 52.6 1.7 17.8 9.9 5.6 8.9 1.5 14.4 9.4 2.1 0.1 20.1 6.7 17.4 20.6 34.5 36.3 4.5 14.6 1.9 4.3 9.4 2.1 58.2 26.8 24.9 0.7 14.6 6.7 2.6 41.9 6.2 1.8 37.8 1.1 33.6 10.2 49.7 1.6 35.4 37.7 19.4 0.1 1.4 4.4 2.5 1.4 27.2 4.0 0.5 0.8 2.0 16.8 16.8 14.3 31.5 12.2 4.2 4.2 6.4 32.9 15.1 1.2 7.3 6.4 15.9 0.7 5.0 1.3 2.4 4.9 12.8 7.5 10.9 0.1 0.4 0.7 0.3 0.1 0.1 0.2 0.1 0.3 0.5 0.7 0.2 0.2 0.6 0.1 0.4 0.0 0.9 1.0 5.6 6.1 6.9 13.9 6.3 11.6 6.4 7.7 9.2 5.1 6.5 5.6 3.9 0.0 5.8 5.5 8.4 8.8 190.1 17.0 7.4 5.2 41.6 28.7 6.3 4.3 20.3 165.5 10.4 86.5 14.6 9.0 37.2 8.4 16.5 75.1 18.7 5.9 36.8 8.8 20.3 3.3 6.2 5.6 37.8 145.2 7.0 23.9 2.9 1.3 14.7 10.1 41.8 24.5 12.2 0.6 3.6 3.2 0.3 9.3 10.6 7.5 0.9 40.5 1.0 9.0 9.2 5.0 5.0 0.4 5.7 95.4 72.8 220.9 3.0 17.6 6.6 6.2 8.9 8.4 3.4 9.7 5.4 601.3 15.1 2.2 8.7 165.2 ARHGAP20 KIAA1391 ENSG00000137727 "Rho GTPase activating protein 20" Q9P2F6 11 110577042-110713189 "Disease related genes, Predicted intracellular proteins" "GTPase activation" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 78.0;Excitatory neurons: 97.9;Inhibitory neurons: 159.9;Leydig cells: 48.7;Oligodendrocyte precursor cells: 90.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 24.6;ASC TERT1: 8.2;HHSteC: 5.5;SiHa: 7.2;U-2197: 4.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038458, HPA038459, HPA076303" Uncertain Approved Mitochondria NA NA "Cluster 71: Testis - DNA repair" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA038458: AB_10672517, HPA038459: AB_2676022, HPA076303: AB_2686792" "unprognostic (1.69e-2)" "unprognostic (3.97e-2)" "unprognostic (6.83e-2)" "unprognostic (1.34e-1)" "unprognostic (2.66e-1)" "unprognostic (8.47e-3)" "unprognostic (2.75e-1)" "unprognostic (2.90e-2)" "unprognostic (4.15e-2)" "unprognostic (5.70e-2)" "unprognostic (1.38e-1)" "unprognostic (9.52e-2)" "unprognostic (2.82e-5)" "unprognostic (1.84e-2)" "unprognostic (9.15e-2)" "unprognostic (6.21e-3)" "unprognostic (4.10e-2)" 8.9 2.3 3.8 1.3 4.1 0.0 4.5 1.8 3.5 4.4 0.3 1.9 0.8 4.4 3.6 2.2 3.1 2.2 0.4 3.5 2.5 0.3 1.7 4.1 1.2 0.5 0.7 1.2 0.2 0.8 0.9 1.7 0.5 3.9 2.8 1.1 1.3 8.8 0.9 1.0 1.5 3.3 1.2 1.3 1.8 8.3 2.0 0.4 4.8 1.3 0.8 3.2 2.2 0.8 0.0 0.0 0.0 0.0 24.6 8.2 0.0 1.1 3.3 0.4 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.2 0.1 0.3 0.0 5.5 0.0 0.0 3.0 0.0 0.0 0.0 0.1 2.4 0.2 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 2.1 0.3 7.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 4.4 0.0 0.1 0.0 2.1 0.9 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 4.1 1.8 3.5 3.5 2.5 0.5 0.7 0.5 1.2 2.0 0.8 1.7 0.0 2.3 5.2 1.7 0.8 4.9 1.1 10.2 9.9 0.5 6.0 0.9 1.5 2.5 0.0 0.0 0.1 0.0 0.0 0.0 0.2 13.1 1.7 78.0 4.3 0.0 0.0 97.9 0.4 0.1 15.1 0.0 1.2 1.3 1.1 9.7 2.0 0.2 3.3 159.9 0.2 0.0 0.8 1.6 4.6 48.7 2.1 3.6 22.5 0.0 0.7 0.0 90.0 3.2 0.7 0.0 36.5 1.2 1.9 0.0 0.0 0.0 1.4 0.0 2.3 4.6 11.8 11.7 1.6 0.4 0.7 0.5 3.6 0.0 0.8 ARMC1 "Arcp, FLJ10511" ENSG00000104442 "Armadillo repeat containing 1" Q9NVT9 8 65602458-65634217 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026085 Approved Approved Mitochondria NA NA "Cluster 34: Basophils - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA026085: AB_1845031" "prognostic unfavorable (4.81e-4)" "unprognostic (1.35e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (2.87e-4)" "unprognostic (8.18e-2)" "unprognostic (1.45e-2)" "prognostic unfavorable (7.73e-4)" "unprognostic (4.13e-2)" "unprognostic (7.49e-2)" "unprognostic (2.19e-2)" "prognostic unfavorable (9.15e-4)" "unprognostic (1.81e-1)" "unprognostic (3.30e-3)" "unprognostic (1.08e-1)" "unprognostic (1.07e-1)" "unprognostic (1.98e-1)" "unprognostic (1.66e-1)" 16.6 15.4 19.0 13.5 23.8 13.1 18.4 21.0 29.0 15.2 16.4 16.4 15.6 18.6 16.4 16.8 13.2 11.9 21.6 19.7 21.7 22.0 23.2 12.4 19.3 19.8 20.9 18.8 14.9 21.0 9.0 15.0 20.4 17.8 16.6 12.5 15.7 16.9 19.2 11.5 13.7 21.6 20.4 13.9 13.6 9.4 20.8 22.3 14.7 24.6 20.3 16.8 10.8 25.6 51.3 35.6 34.2 32.0 33.1 30.1 24.8 44.7 33.2 46.5 34.2 26.5 40.3 79.0 11.2 41.0 50.7 33.4 61.9 35.9 62.9 45.0 31.7 61.3 20.6 38.9 44.1 23.4 32.0 27.8 40.9 38.3 52.5 36.6 48.5 55.3 64.5 54.7 50.6 32.9 86.9 30.7 35.7 63.6 38.9 49.9 42.6 27.9 37.2 23.8 25.3 27.3 28.5 35.4 44.3 34.6 56.9 27.2 28.5 43.8 32.1 33.8 42.5 40.3 45.2 53.2 41.5 42.8 43.7 36.3 5.6 7.4 8.3 9.3 11.4 9.8 9.9 10.2 7.2 6.9 9.9 10.1 0.7 11.5 9.2 6.4 11.4 6.5 19.0 23.8 21.0 29.0 19.7 21.7 19.8 20.9 20.4 20.4 20.8 25.6 26.6 41.7 27.7 16.0 33.0 15.8 12.1 17.5 19.4 23.7 20.7 19.4 33.4 18.6 24.5 16.5 22.9 35.0 32.9 14.4 54.8 28.3 10.4 15.9 26.9 23.7 23.4 62.7 23.9 28.1 43.9 24.4 20.4 15.3 10.8 31.5 21.4 25.6 25.0 20.2 22.7 17.0 24.4 18.9 12.6 5.7 26.1 20.6 21.4 19.7 31.6 47.3 24.7 15.1 47.7 28.0 13.0 33.4 27.2 18.9 19.9 47.7 17.6 21.9 6.6 29.0 32.2 50.7 24.5 29.9 18.5 37.6 28.0 28.1 23.4 9.1 ARMC10 "MGC3195, SVH" ENSG00000170632 "Armadillo repeat containing 10" Q8N2F6 7 103074881-103099759 "Predicted intracellular proteins, Predicted membrane proteins" "Growth regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011036, HPA011057" Enhanced Enhanced Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 50: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA011036: AB_1080139, HPA011057: AB_1080137" "unprognostic (7.03e-3)" "unprognostic (2.44e-1)" "unprognostic (8.18e-2)" "unprognostic (3.53e-1)" "prognostic unfavorable (8.90e-6)" "unprognostic (3.85e-3)" "prognostic unfavorable (3.58e-4)" "unprognostic (5.57e-2)" "unprognostic (3.49e-2)" "unprognostic (7.90e-2)" "prognostic unfavorable (2.49e-6)" "unprognostic (1.02e-1)" "unprognostic (5.78e-2)" "unprognostic (1.47e-1)" "unprognostic (2.76e-1)" "unprognostic (1.14e-2)" "unprognostic (5.67e-2)" 20.9 22.8 11.2 9.3 11.9 7.2 18.1 10.5 12.7 22.3 12.2 19.4 9.8 17.8 17.0 21.0 18.6 11.3 16.6 11.4 11.9 24.0 24.4 15.5 10.8 10.7 11.4 24.4 24.4 17.2 11.9 10.9 11.4 18.0 12.7 13.8 16.4 15.7 18.4 25.8 12.1 14.4 13.7 12.3 19.8 12.2 11.6 13.6 17.6 8.6 11.5 21.3 19.5 15.9 30.1 25.5 16.1 28.8 30.0 28.4 15.1 19.3 22.2 14.7 17.4 13.7 34.8 57.3 42.4 18.0 43.4 25.6 20.9 23.3 20.9 19.2 22.3 19.4 10.9 7.8 31.9 55.8 21.3 19.3 40.4 18.8 30.2 45.7 33.6 29.6 45.9 32.8 26.5 58.8 38.8 43.9 36.2 54.5 26.8 22.9 15.5 69.2 37.7 20.8 16.3 25.1 30.3 43.8 35.3 26.9 17.6 26.9 23.4 22.9 23.6 52.0 31.8 47.8 77.6 42.9 25.5 50.1 30.2 0.0 2.3 3.8 1.4 3.1 2.2 2.2 2.2 2.2 3.4 3.0 2.3 2.4 0.5 2.1 1.6 3.1 2.4 1.1 11.2 11.9 10.5 12.7 11.4 11.9 10.7 11.4 11.4 13.7 11.6 15.9 30.1 25.6 17.9 12.1 31.8 78.8 60.2 7.9 54.7 24.4 53.3 56.1 17.4 34.3 12.4 27.6 14.6 45.3 41.1 17.6 66.5 19.7 12.6 31.4 32.3 28.4 15.0 51.5 20.7 15.5 52.2 35.4 33.6 23.8 17.2 37.9 30.4 37.6 46.7 8.4 18.5 32.6 6.1 38.8 39.5 8.3 33.8 32.7 46.2 14.0 28.7 38.3 25.7 20.6 44.0 23.2 20.5 34.3 41.9 87.1 21.9 97.4 10.5 28.6 32.9 28.6 37.5 15.6 35.1 67.2 104.3 45.0 31.4 31.9 41.3 71.9 AS3MT CYT19 ENSG00000214435 "Arsenite methyltransferase" Q9HBK9 10 102869470-102901899 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "adrenal gland: 302.4" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.1;Basal squamous epithelial cells: 1.2;Proximal tubular cells: 1.0" "Cancer enhanced" "Detected in single" "liver cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 26.8;REH: 54.6;SH-SY5Y: 27.8;T-47d: 43.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017856 Enhanced Approved Mitochondria NA NA "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 50: Fibroblasts - ECM organization" Mitochondria "HPA017856: AB_1847420" "unprognostic (1.11e-1)" "unprognostic (2.02e-4)" "unprognostic (2.45e-1)" "unprognostic (2.25e-1)" "unprognostic (3.39e-1)" "unprognostic (1.66e-1)" "unprognostic (7.02e-4)" "unprognostic (3.22e-1)" "unprognostic (1.42e-1)" "unprognostic (3.90e-2)" "unprognostic (2.03e-1)" "unprognostic (1.83e-1)" "unprognostic (3.83e-10)" "unprognostic (1.04e-2)" "unprognostic (4.17e-2)" "unprognostic (1.59e-1)" "unprognostic (2.16e-2)" 5.1 302.4 7.4 1.3 7.5 0.7 6.3 11.5 8.7 7.5 9.3 6.4 3.0 7.7 4.4 3.6 5.8 6.7 26.8 6.7 8.4 19.2 59.2 4.0 2.0 7.9 8.3 8.7 11.7 65.7 6.6 1.0 8.0 9.1 1.8 4.8 4.8 5.2 11.4 4.3 3.3 3.9 6.6 18.3 4.7 8.7 7.7 3.7 7.7 15.2 1.6 3.2 5.0 8.3 0.0 7.6 26.8 17.4 0.6 0.6 5.1 8.1 6.7 11.9 14.3 21.3 1.2 0.0 2.4 10.7 0.6 0.4 23.8 1.4 12.4 0.3 6.7 0.0 3.2 20.9 7.7 0.2 0.6 3.7 3.1 1.6 0.0 21.3 0.5 25.3 0.0 0.4 10.8 0.1 4.9 0.7 13.2 0.1 1.0 54.6 0.0 0.2 2.7 0.0 0.4 27.8 0.0 0.4 3.7 8.8 43.9 0.6 0.1 2.6 0.0 3.9 0.0 0.2 0.4 0.0 8.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 7.4 7.5 11.5 8.7 6.7 8.4 7.9 8.3 8.0 6.6 7.7 8.3 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 ATAD3A FLJ10709 ENSG00000197785 "ATPase family AAA domain containing 3A" Q9NVI7 1 1512162-1534685 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058968, HPA064867, HPA065305" Approved Enhanced Mitochondria NA NA 27000 "Cluster 27: Non-specific - Gene expression" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA058968: AB_2683864, HPA064867: AB_2685375, HPA065305: AB_2685459" "unprognostic (8.42e-2)" "unprognostic (1.67e-1)" "unprognostic (3.11e-1)" "unprognostic (1.46e-1)" "unprognostic (2.50e-1)" "unprognostic (8.74e-2)" "prognostic unfavorable (5.90e-5)" "unprognostic (6.62e-2)" "unprognostic (9.53e-2)" "unprognostic (5.81e-2)" "unprognostic (4.09e-2)" "unprognostic (7.66e-2)" "unprognostic (1.17e-2)" "unprognostic (1.11e-1)" "unprognostic (3.09e-1)" "unprognostic (6.25e-2)" "unprognostic (1.87e-3)" 10.9 13.6 8.3 12.3 8.4 18.1 10.7 8.5 11.1 10.6 9.7 11.2 11.4 12.8 2.0 17.2 10.4 4.4 15.5 9.0 7.7 10.6 18.5 10.0 10.4 8.4 8.2 8.4 19.5 5.2 14.6 6.6 8.0 9.5 3.0 2.0 13.4 5.5 28.8 14.3 9.8 3.8 7.5 11.7 12.9 9.3 8.2 6.2 9.6 8.3 4.7 11.4 10.7 8.3 79.2 47.9 18.0 49.3 8.3 10.6 45.6 62.9 16.8 52.7 32.1 127.2 52.8 45.9 41.5 24.9 19.7 65.8 27.5 36.5 9.2 42.7 110.3 75.0 131.9 97.0 17.3 112.5 42.7 12.8 11.2 44.2 16.2 6.1 23.2 44.2 120.1 27.3 19.7 64.5 83.1 95.2 40.9 25.9 91.5 88.5 35.7 91.9 14.7 40.3 91.8 35.3 39.8 58.1 53.0 5.9 24.8 55.7 32.6 52.5 45.0 85.8 79.2 45.6 52.6 172.7 54.2 160.5 25.4 0.5 1.8 0.6 1.5 1.5 1.0 1.4 1.5 1.7 2.2 1.5 1.3 0.6 0.1 2.5 3.4 2.2 1.5 1.1 8.3 8.4 8.5 11.1 9.0 7.7 8.4 8.2 8.0 7.5 8.2 8.3 8.5 3.2 9.0 10.7 11.7 20.4 11.2 5.9 8.0 10.5 11.6 8.3 9.5 8.6 6.4 7.3 6.2 21.6 10.0 18.8 7.9 22.5 9.5 14.7 9.3 11.8 13.8 28.4 8.8 21.3 43.4 10.4 13.7 8.7 8.9 21.9 4.6 12.5 22.4 23.5 8.3 19.6 14.2 7.5 12.5 10.1 5.6 7.7 16.0 6.5 5.9 10.9 6.2 4.5 6.1 25.3 5.2 7.9 27.5 38.3 13.8 12.8 7.9 9.4 0.0 9.4 14.8 5.8 20.1 17.4 24.3 19.7 7.7 35.6 27.7 15.7 ATAD3B "KIAA1273, TOB3" ENSG00000160072 "ATPase family AAA domain containing 3B" Q5T9A4 1 1471765-1497848 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "HPA058968, HPA064867, HPA065305" Approved Enhanced Mitochondria NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA058968: AB_2683864, HPA064867: AB_2685375, HPA065305: AB_2685459" "unprognostic (6.05e-2)" "unprognostic (1.95e-1)" "unprognostic (6.54e-2)" "unprognostic (1.30e-1)" "unprognostic (1.97e-2)" "unprognostic (3.68e-1)" "prognostic unfavorable (1.81e-5)" "unprognostic (1.51e-1)" "unprognostic (2.27e-2)" "unprognostic (2.17e-2)" "unprognostic (8.24e-3)" "unprognostic (3.13e-2)" "prognostic unfavorable (5.48e-9)" "unprognostic (2.38e-2)" "unprognostic (2.80e-1)" "unprognostic (3.00e-2)" "unprognostic (1.68e-1)" 9.1 10.0 5.7 3.6 5.8 5.0 8.5 5.5 9.7 9.8 5.8 9.1 2.4 7.2 0.0 12.4 9.1 0.7 8.0 5.6 5.6 13.7 15.7 8.6 3.5 5.9 5.5 10.2 9.7 0.4 13.6 1.3 5.9 11.7 0.3 0.1 7.5 0.7 6.2 10.7 9.2 0.5 5.3 14.1 8.7 10.8 6.0 2.3 9.6 0.2 0.7 9.9 8.6 6.1 13.4 0.1 3.2 21.9 1.3 1.4 29.0 20.7 4.8 20.7 15.7 47.8 38.6 16.9 6.7 7.9 13.4 21.8 28.1 13.6 4.7 16.3 29.0 12.2 32.9 31.9 5.3 20.4 14.3 4.7 0.7 35.9 1.5 0.0 7.6 7.1 37.2 3.2 8.1 5.4 26.3 28.7 44.1 9.8 51.7 21.5 6.3 12.0 6.2 7.7 15.6 13.2 14.0 18.7 20.2 2.4 2.4 7.5 7.5 4.5 12.0 32.4 23.0 12.2 18.5 45.7 17.7 35.1 5.8 0.2 0.2 0.4 0.4 1.1 0.5 0.1 0.3 0.4 0.2 0.0 0.1 0.0 0.0 0.0 0.6 0.1 0.0 0.1 5.7 5.8 5.5 9.7 5.6 5.6 5.9 5.5 5.9 5.3 6.0 6.1 8.6 6.4 22.1 17.6 9.4 26.3 7.8 5.2 10.2 16.0 9.3 7.1 5.9 8.6 7.5 9.2 20.9 15.3 12.9 17.8 1.9 7.7 3.6 10.1 7.8 8.2 7.2 7.6 13.3 7.9 40.3 8.7 23.9 10.2 11.4 16.7 4.2 7.6 12.4 13.5 12.9 13.8 6.1 4.7 12.3 3.8 4.4 7.9 10.6 8.4 5.4 5.8 1.0 4.5 8.3 11.3 9.7 3.0 22.8 14.4 6.7 2.6 8.3 17.1 6.6 8.3 10.2 5.4 10.6 11.1 23.4 17.8 9.9 15.0 20.6 10.8 ATAD3C FLJ34599 ENSG00000215915 "ATPase family AAA domain containing 3C" Q5T2N8 1 1449689-1470163 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 19.8;Collecting duct cells: 20.2;Distal tubular cells: 45.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 4 "RPMI-8226: 13.1" HPA065305 Approved Mitochondria NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA065305: AB_2685459" "unprognostic (9.23e-2)" "unprognostic (3.48e-2)" "unprognostic (3.20e-2)" "unprognostic (4.35e-3)" "unprognostic (1.11e-2)" "unprognostic (1.71e-2)" "unprognostic (3.79e-2)" "prognostic favorable (5.15e-4)" "unprognostic (1.23e-1)" "unprognostic (1.57e-1)" "unprognostic (1.22e-1)" "unprognostic (2.65e-1)" "unprognostic (3.80e-2)" "unprognostic (1.83e-1)" "unprognostic (5.74e-2)" "unprognostic (2.22e-1)" "unprognostic (2.12e-3)" 1.1 0.2 5.3 0.9 6.3 0.5 1.6 5.2 6.4 2.0 4.3 2.3 0.6 1.7 1.2 1.1 2.0 0.7 0.9 5.5 6.2 4.3 5.2 1.5 0.4 6.7 6.0 1.1 4.6 0.1 1.8 0.3 6.4 4.0 0.3 1.2 2.6 2.0 0.2 0.8 0.8 0.7 5.5 0.4 0.7 1.2 6.1 0.4 4.0 0.0 0.5 2.9 1.4 10.1 0.2 0.0 0.2 0.3 0.3 0.0 0.2 0.1 0.0 0.2 0.0 1.2 2.5 0.2 0.3 0.1 0.1 0.3 1.0 0.4 0.1 0.1 1.0 0.2 0.9 1.6 0.2 0.2 0.2 0.0 0.1 0.1 0.7 0.0 0.0 0.3 0.2 3.0 0.1 0.7 0.3 0.8 0.5 0.1 0.2 0.3 0.1 13.1 0.8 0.2 2.0 0.7 0.0 0.5 0.1 2.1 2.6 0.2 0.2 0.1 0.2 0.3 0.1 1.4 2.1 0.4 0.1 0.3 0.0 0.8 0.1 0.3 0.3 0.1 1.2 0.5 0.4 0.3 0.0 0.3 0.5 0.4 0.5 0.5 0.1 0.1 0.6 0.2 5.3 6.3 5.2 6.4 5.5 6.2 6.7 6.0 6.4 5.5 6.1 10.1 2.5 6.4 19.8 0.7 4.2 3.4 3.5 1.3 4.6 5.0 17.4 14.4 4.6 0.0 2.7 20.2 16.7 0.7 2.0 2.0 45.0 5.3 0.4 3.6 3.8 4.2 4.2 0.0 1.0 9.2 0.3 1.8 0.0 6.1 3.8 0.6 1.8 6.8 1.8 6.7 0.6 1.9 0.0 2.9 2.5 1.4 1.2 0.7 3.6 2.8 0.5 2.8 4.1 1.0 10.8 4.4 0.3 4.9 8.4 3.0 1.3 16.2 1.3 9.1 0.0 7.3 1.6 0.5 1.5 1.5 5.7 0.8 3.6 4.2 1.3 3.1 ATP5F1A "ATP5A, ATP5A1, ATP5AL2, ATPM, hATP1, OMR, ORM" ENSG00000152234 "ATP synthase F1 subunit alpha" P25705 18 46080248-46104334 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 1760.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 784.3;Distal tubular cells: 1173.9;Extravillous trophoblasts: 463.0;Proximal tubular cells: 939.6;Syncytiotrophoblasts: 578.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013067, HPA040622, HPA044202" Enhanced Supported Mitochondria NA NA 8800000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "CAB013067: AB_221511, HPA040622: AB_2677048, HPA044202: AB_2678855" "unprognostic (3.08e-2)" "unprognostic (9.13e-2)" "unprognostic (1.84e-2)" "unprognostic (3.54e-1)" "unprognostic (6.36e-2)" "unprognostic (2.61e-1)" "unprognostic (1.89e-2)" "unprognostic (6.79e-2)" "unprognostic (8.31e-2)" "unprognostic (4.79e-2)" "unprognostic (7.30e-3)" "unprognostic (1.50e-2)" "prognostic favorable (1.22e-15)" "unprognostic (4.60e-3)" "unprognostic (2.06e-1)" "unprognostic (1.77e-1)" "unprognostic (4.87e-3)" 251.3 453.6 198.6 177.7 209.2 210.5 260.4 233.0 251.4 195.5 401.9 414.0 438.9 192.6 225.6 362.6 227.2 146.3 1498.3 207.7 246.0 730.4 441.6 175.1 223.7 234.6 237.8 211.1 299.9 868.5 277.4 201.7 226.0 211.4 419.8 465.4 307.4 265.9 1602.0 290.3 335.0 233.0 205.4 226.8 419.1 167.6 226.7 277.3 261.4 1760.3 337.6 244.9 224.7 209.6 355.2 353.0 459.6 434.3 546.0 601.8 508.6 399.5 562.4 601.0 522.8 532.7 271.9 833.2 238.9 487.4 322.3 641.7 801.1 614.1 556.4 373.0 450.3 551.7 413.3 667.2 357.1 1182.7 501.6 559.2 422.3 434.6 448.2 481.3 630.4 442.5 454.0 477.2 521.8 367.6 612.8 579.7 432.3 344.5 367.6 596.5 533.8 1131.4 816.2 849.7 465.7 434.7 293.3 361.5 506.9 428.6 466.3 679.3 370.4 328.7 282.7 174.9 354.9 542.5 501.5 533.0 328.1 698.0 358.7 119.1 573.9 162.7 353.6 511.8 455.9 492.3 422.7 388.4 959.5 392.9 503.3 421.7 55.9 414.5 485.1 468.3 527.4 1339.1 198.6 209.2 233.0 251.4 207.7 246.0 234.6 237.8 226.0 205.4 226.7 209.6 79.2 169.9 167.8 0.0 49.9 0.0 0.0 0.0 0.0 0.0 205.7 169.8 0.0 0.0 100.3 171.0 0.0 784.3 86.3 0.0 1173.9 358.3 0.0 125.3 163.3 73.0 0.0 0.0 0.0 269.7 463.0 97.8 0.0 119.3 89.6 198.7 0.0 0.0 409.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 87.5 0.0 0.0 179.9 0.0 0.0 0.0 0.0 199.1 0.0 0.0 24.0 0.0 0.0 939.6 95.5 0.0 0.0 0.0 87.1 0.0 0.0 0.0 0.0 578.2 54.6 319.2 0.0 0.0 ATP5F1B "ATP5B, ATPSB" ENSG00000110955 "ATP synthase F1 subunit beta" P06576 12 56638175-56645984 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 2590.4;tongue: 3205.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 821.1;Distal tubular cells: 1238.5;Extravillous trophoblasts: 592.7;Hofbauer cells: 608.9;Proximal tubular cells: 951.7;Syncytiotrophoblasts: 1138.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001520, HPA001528, CAB017527" Enhanced Enhanced Mitochondria NA NA 19000000 "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 7: Non-specific - Mitochondria" Mitochondria "CAB017527: AB_1121153, HPA001520: AB_1078243, HPA001528: AB_1078242" "prognostic unfavorable (7.17e-6)" "unprognostic (5.69e-2)" "unprognostic (1.08e-2)" "unprognostic (7.24e-2)" "unprognostic (8.39e-2)" "unprognostic (1.84e-2)" "unprognostic (2.12e-3)" "unprognostic (1.92e-2)" "unprognostic (8.19e-3)" "unprognostic (2.38e-2)" "unprognostic (1.44e-2)" "unprognostic (2.11e-2)" "prognostic favorable (1.43e-9)" "unprognostic (2.79e-1)" "unprognostic (3.22e-1)" "unprognostic (1.33e-1)" "unprognostic (3.30e-2)" 432.7 555.5 217.6 300.5 231.4 465.8 301.5 281.6 303.8 241.8 443.3 741.6 689.5 235.4 223.4 527.6 277.9 225.7 2011.6 233.0 307.1 945.9 609.3 253.4 294.6 264.2 242.9 200.2 301.7 1311.6 252.6 301.4 280.4 280.9 767.6 484.2 407.7 356.4 2590.4 398.6 575.5 332.5 230.9 272.5 494.9 236.0 277.5 390.9 342.8 3205.3 458.3 404.1 311.2 244.7 693.6 834.9 632.3 1003.6 578.3 596.7 1159.8 683.2 645.6 1179.1 663.9 1375.7 755.6 1236.3 723.0 863.5 482.9 906.1 1378.1 851.5 1039.4 579.9 987.5 1333.1 726.4 872.5 716.6 1509.7 912.9 755.1 843.3 918.0 1171.2 870.2 985.8 901.7 1246.3 1363.1 992.2 671.5 1134.4 941.3 1085.9 905.6 1637.6 1079.3 711.0 1603.5 1315.6 1196.7 737.5 658.2 1042.3 1481.3 1214.0 663.4 1404.1 1151.8 657.6 454.8 507.9 671.9 751.0 659.5 865.7 1254.8 684.7 1007.8 718.4 403.5 549.4 281.8 293.5 643.6 326.3 303.2 275.4 313.6 713.4 248.4 221.0 266.8 137.1 296.9 750.6 360.9 372.9 1077.1 217.6 231.4 281.6 303.8 233.0 307.1 264.2 242.9 280.4 230.9 277.5 244.7 172.3 134.6 173.2 0.0 48.6 0.0 0.0 0.0 0.0 0.0 176.8 149.1 0.0 0.0 81.1 277.7 0.0 821.1 141.5 0.0 1238.5 517.7 0.0 194.1 169.2 115.7 0.0 0.0 0.0 367.9 592.7 115.0 0.0 163.3 145.1 267.6 0.0 0.0 608.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 136.3 0.0 0.0 281.2 0.0 0.0 0.0 0.0 333.3 0.0 0.0 26.8 0.0 0.0 951.7 102.7 0.0 0.0 0.0 151.1 0.0 0.0 0.0 0.0 1138.6 77.4 518.4 0.0 0.0 ATP5IF1 "ATPI, ATPIF1, ATPIP, IP, MGC1167, MGC8898" ENSG00000130770 "ATP synthase inhibitory factor subunit 1" Q9UII2 1 28236109-28246906 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 1035.0;Endometrial ciliated cells: 1524.2;Exocrine glandular cells: 672.1;Granulosa cells: 1030.6;Proximal tubular cells: 1502.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027999 Supported Enhanced Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "HPA027999: AB_10600984" "unprognostic (2.80e-2)" "unprognostic (3.72e-2)" "unprognostic (2.95e-1)" "prognostic favorable (6.38e-8)" "unprognostic (2.04e-1)" "unprognostic (1.76e-1)" "unprognostic (6.57e-2)" "unprognostic (2.93e-2)" "unprognostic (1.40e-2)" "prognostic favorable (8.20e-4)" "unprognostic (5.94e-2)" "unprognostic (3.52e-1)" "unprognostic (6.15e-3)" "unprognostic (4.68e-2)" "unprognostic (2.02e-1)" "unprognostic (2.79e-1)" "unprognostic (1.48e-3)" 96.9 215.1 98.4 50.6 98.6 144.3 108.8 95.6 140.0 123.3 95.2 234.8 163.1 113.0 44.5 184.5 139.4 28.0 585.8 100.0 106.5 384.9 342.6 116.0 64.5 99.6 96.8 134.9 163.4 90.1 246.5 37.6 97.8 156.0 59.4 71.0 145.3 37.1 456.7 165.0 199.6 28.5 93.7 153.7 215.7 355.5 99.6 60.0 169.2 179.8 47.9 116.6 134.0 104.1 271.9 136.4 79.3 75.1 58.0 62.7 94.1 118.6 57.9 98.6 96.2 132.0 192.5 189.1 173.8 72.1 37.6 161.5 91.2 118.0 77.6 143.9 306.0 162.9 612.7 180.8 62.9 125.5 158.1 73.5 190.2 88.2 70.4 96.2 95.7 222.0 292.9 167.9 71.2 178.0 187.6 230.4 262.7 100.9 167.8 177.3 87.5 270.2 196.9 175.5 158.9 114.2 146.5 150.8 160.4 76.5 224.4 136.6 100.6 31.9 88.0 126.5 142.1 432.0 282.8 268.6 151.1 338.8 38.1 133.3 116.6 126.1 144.2 111.1 145.8 195.2 154.3 155.5 142.8 154.0 144.1 139.3 102.7 142.9 102.7 213.5 226.9 214.1 98.4 98.6 95.6 140.0 100.0 106.5 99.6 96.8 97.8 93.7 99.6 104.1 207.3 205.1 284.9 0.0 61.7 0.0 0.0 0.0 0.0 0.0 251.1 314.3 0.0 0.0 150.4 546.2 0.0 453.8 165.4 0.0 1035.0 396.6 0.0 1524.2 210.6 84.0 0.0 0.0 0.0 672.1 226.0 114.6 0.0 453.2 172.8 1030.6 0.0 0.0 372.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 108.6 0.0 0.0 123.0 0.0 0.0 0.0 0.0 550.3 0.0 0.0 30.3 0.0 0.0 1502.7 621.6 0.0 0.0 0.0 90.6 0.0 0.0 0.0 0.0 251.7 92.0 281.6 0.0 0.0 ATP5MD "bA792D24.4, DAPIT, MGC14697, USMG5" ENSG00000173915 "ATP synthase membrane subunit DAPIT" Q96IX5 10 103389041-103396492 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 1340.2;Ductal cells: 705.9;Exocrine glandular cells: 723.1;Pancreatic endocrine cells: 884.5;Proximal tubular cells: 1879.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044798 Supported Mitochondria NA NA 55000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA044798: AB_2679091" "unprognostic (4.41e-2)" "unprognostic (3.08e-2)" "unprognostic (2.59e-1)" "unprognostic (7.93e-2)" "unprognostic (1.65e-1)" "unprognostic (1.95e-2)" "unprognostic (1.63e-1)" "unprognostic (1.51e-1)" "unprognostic (5.67e-2)" "unprognostic (1.57e-2)" "unprognostic (7.41e-2)" "unprognostic (1.01e-1)" "unprognostic (3.32e-2)" "unprognostic (1.74e-1)" "unprognostic (4.66e-2)" "unprognostic (7.46e-2)" "unprognostic (1.03e-2)" 332.3 343.0 502.9 155.1 517.7 193.0 324.6 514.9 721.8 215.1 515.2 484.6 273.5 176.9 410.2 426.1 194.3 140.8 1229.7 526.1 539.0 546.7 587.1 215.3 180.3 501.2 501.9 157.5 321.4 519.2 309.2 157.4 506.1 254.2 449.6 245.3 234.8 236.4 1019.3 204.6 261.7 229.8 511.8 185.4 369.8 142.5 509.3 319.0 191.2 1325.5 251.0 284.7 258.9 518.0 557.8 559.4 528.4 648.2 570.2 696.0 348.3 523.2 612.7 501.0 556.6 925.2 605.3 312.4 288.9 575.3 398.6 559.4 502.2 522.7 697.9 414.7 887.3 331.8 682.1 1057.7 545.7 688.3 491.3 569.2 801.1 456.4 715.7 849.2 661.5 470.0 441.5 517.5 849.4 842.0 552.0 1167.5 397.8 830.1 959.1 355.8 326.0 495.3 1218.4 878.4 203.7 464.8 269.4 419.7 824.9 723.5 373.4 619.9 388.6 255.2 394.2 394.0 692.8 537.2 958.4 543.5 545.2 678.2 200.3 575.3 271.2 395.8 214.7 384.0 248.0 301.6 296.3 259.8 314.1 219.1 251.4 256.7 231.1 230.5 375.3 456.3 307.9 304.4 502.9 517.7 514.9 721.8 526.1 539.0 501.2 501.9 506.1 511.8 509.3 518.0 169.1 211.5 173.2 0.0 40.9 0.0 0.0 0.0 0.0 0.0 323.4 417.6 0.0 0.0 91.0 388.1 0.0 298.0 76.3 0.0 1340.2 705.9 0.0 406.0 245.4 114.5 0.0 0.0 0.0 723.1 439.4 81.8 0.0 424.5 118.6 176.9 0.0 0.0 543.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 166.4 0.0 0.0 432.6 0.0 0.0 0.0 0.0 884.5 0.0 0.0 0.0 0.0 0.0 1879.7 121.0 0.0 0.0 0.0 127.9 0.0 0.0 0.0 0.0 305.8 69.4 209.9 0.0 0.0 ATP5ME ATP5I ENSG00000169020 "ATP synthase membrane subunit e" P56385 4 672436-674330 "Metabolic proteins, Predicted intracellular proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 2048.3" "Cell type enhanced" "Detected in many" "Collecting duct cells: 886.5;Distal tubular cells: 1729.5;Proximal tubular cells: 2485.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035010 Enhanced Supported Mitochondria NA NA 280000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA035010: AB_10669853" "unprognostic (1.42e-1)" "unprognostic (4.93e-2)" "unprognostic (1.46e-1)" "unprognostic (1.66e-1)" "unprognostic (3.44e-1)" "unprognostic (1.23e-1)" "unprognostic (6.95e-2)" "unprognostic (7.92e-2)" "unprognostic (3.32e-1)" "unprognostic (1.35e-3)" "unprognostic (1.21e-2)" "unprognostic (2.41e-2)" "unprognostic (2.46e-3)" "unprognostic (6.89e-2)" "unprognostic (2.18e-1)" "unprognostic (2.48e-1)" "unprognostic (6.45e-3)" 360.1 412.7 940.1 212.2 960.8 312.4 277.4 981.5 1172.2 263.3 926.5 555.7 460.3 237.4 242.7 511.9 218.8 94.5 1507.7 932.5 968.9 572.0 591.7 235.6 174.6 980.1 955.6 257.5 330.9 774.8 312.8 144.8 972.5 262.0 331.4 336.4 304.8 220.4 2048.3 297.8 436.7 172.8 952.6 281.3 414.9 130.6 960.4 315.7 270.1 1688.5 223.8 293.5 323.8 998.1 542.0 560.8 781.7 599.5 622.4 544.4 390.7 561.8 445.4 407.4 359.4 525.4 548.4 299.0 472.8 612.4 683.8 361.8 668.9 924.1 241.4 249.9 1082.7 854.6 1107.9 1435.2 659.0 1118.6 368.0 721.6 533.5 472.2 491.0 665.5 503.3 608.1 756.0 314.4 464.7 904.5 972.6 1337.3 861.9 1071.7 1438.9 584.4 555.0 620.7 863.9 1053.2 667.7 530.1 401.6 525.0 620.2 502.7 590.4 695.7 580.2 348.0 340.7 308.2 730.9 739.7 1273.2 947.0 528.0 712.7 391.3 1049.3 1044.5 1188.8 742.1 920.0 776.3 1470.4 909.2 839.0 1067.0 1131.6 837.1 811.9 962.2 943.5 822.7 1179.7 1086.3 1456.6 940.1 960.8 981.5 1172.2 932.5 968.9 980.1 955.6 972.5 952.6 960.4 998.1 311.8 153.8 199.7 0.0 88.6 0.0 0.0 0.0 0.0 0.0 461.7 421.8 0.0 0.0 121.9 886.5 0.0 404.9 188.8 0.0 1729.5 467.4 0.0 468.6 315.6 125.1 0.0 0.0 0.0 692.9 335.8 139.4 0.0 484.2 122.4 311.8 0.0 0.0 676.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 201.6 0.0 0.0 278.1 0.0 0.0 0.0 0.0 509.6 0.0 0.0 50.1 0.0 0.0 2485.3 183.6 0.0 0.0 0.0 156.7 0.0 0.0 0.0 0.0 274.9 97.8 146.6 0.0 0.0 ATP5MF-PTCD1 ATP5J2-PTCD1 ENSG00000248919 "ATP5MF-PTCD1 readthrough" 7 99419749-99466197 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA020106, HPA047679" Uncertain Approved Mitochondria NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 11: Alveolar cells - Smell perception" Mitochondria "HPA020106: AB_2176551, HPA047679: AB_2680119" "unprognostic (1.15e-3)" "unprognostic (3.63e-2)" "unprognostic (1.73e-1)" "unprognostic (2.83e-1)" "unprognostic (3.29e-2)" "unprognostic (3.51e-1)" "unprognostic (1.18e-3)" "unprognostic (2.84e-2)" "unprognostic (6.44e-2)" "unprognostic (2.18e-1)" "unprognostic (3.50e-2)" "unprognostic (1.28e-1)" "unprognostic (1.70e-1)" "unprognostic (2.04e-1)" "unprognostic (7.45e-2)" "unprognostic (2.00e-2)" "unprognostic (7.50e-2)" 2.8 2.8 1.2 2.8 1.0 0.0 2.3 1.1 1.8 3.3 1.1 3.7 2.7 3.0 1.6 4.7 3.3 2.0 3.7 1.0 1.2 1.7 2.7 1.8 2.6 1.3 1.4 2.5 2.5 3.6 1.7 2.5 1.3 3.7 2.1 0.5 2.5 3.5 8.9 2.7 2.2 2.5 0.9 2.3 2.7 3.4 1.2 2.3 2.3 5.5 2.5 4.1 3.3 1.1 7.7 8.2 6.8 19.1 8.1 4.8 14.6 5.1 6.2 12.8 11.6 31.5 12.3 10.0 12.6 4.9 11.9 7.3 11.6 10.6 5.4 11.2 10.9 5.8 5.0 6.5 8.5 8.0 5.7 8.2 9.4 11.5 9.3 4.7 5.3 11.5 19.5 14.9 8.3 15.7 18.5 10.2 11.9 13.2 10.5 9.9 6.3 26.6 6.7 2.4 8.7 8.8 11.0 18.0 11.0 4.5 9.2 12.5 3.3 8.9 7.8 18.7 13.8 11.7 10.8 16.0 6.5 8.9 16.3 1.3 4.0 1.2 3.3 5.4 3.4 2.1 2.7 2.8 5.6 2.4 2.8 3.6 0.3 4.5 3.2 2.7 2.2 5.0 1.2 1.0 1.1 1.8 1.0 1.2 1.3 1.4 1.3 0.9 1.2 1.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 ATP5MG "ATP5JG, ATP5L" ENSG00000167283 "ATP synthase membrane subunit g" O75964 11 118401606-118431496 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1407.2;Distal tubular cells: 2907.4;Hofbauer cells: 1367.3;Proximal tubular cells: 2520.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA044629 Approved Supported Mitochondria NA NA 44000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA044629: AB_2679028" "unprognostic (1.70e-1)" "unprognostic (2.40e-2)" "unprognostic (2.21e-1)" "unprognostic (5.45e-2)" "unprognostic (1.61e-1)" "unprognostic (3.27e-2)" "unprognostic (3.90e-2)" "unprognostic (8.19e-2)" "unprognostic (5.13e-2)" "unprognostic (1.01e-1)" "unprognostic (1.90e-1)" "unprognostic (7.41e-2)" "prognostic favorable (4.09e-5)" "unprognostic (6.26e-2)" "unprognostic (2.56e-1)" "unprognostic (1.50e-2)" "unprognostic (3.05e-2)" 119.8 137.2 154.2 103.3 158.5 165.6 132.5 158.5 184.3 81.1 168.3 153.6 146.4 79.3 143.3 116.9 96.5 68.1 329.8 157.2 160.8 205.1 154.5 77.9 150.0 155.5 153.1 112.0 110.9 140.7 49.5 83.7 154.0 83.5 164.3 100.8 133.9 92.2 340.7 55.3 118.2 95.2 153.6 86.0 112.3 46.9 155.5 204.1 87.5 373.6 183.1 105.3 41.5 154.7 163.1 87.9 209.3 183.1 167.6 198.0 200.1 149.0 175.9 138.4 146.6 259.9 259.9 314.3 352.7 167.5 206.2 190.4 204.4 214.8 155.3 247.6 138.0 472.8 112.5 197.4 175.3 279.3 210.2 207.1 203.4 169.0 162.9 164.1 189.8 216.6 227.4 253.1 199.5 305.8 365.2 497.3 130.1 427.9 224.0 247.0 174.9 422.9 371.1 260.3 184.3 161.9 232.3 361.1 161.9 221.6 303.0 307.7 172.8 123.0 144.7 109.2 190.9 112.8 184.8 402.1 93.8 353.0 154.7 325.4 437.2 299.0 241.8 360.8 339.7 462.7 398.8 321.5 481.2 378.5 472.9 379.7 214.8 357.2 333.3 534.3 464.5 1112.1 154.2 158.5 158.5 184.3 157.2 160.8 155.5 153.1 154.0 153.6 155.5 154.7 324.3 362.2 364.1 0.0 211.2 0.0 0.0 0.0 0.0 0.0 893.9 1061.2 0.0 0.0 166.5 610.6 0.0 1407.2 378.3 0.0 2907.4 748.6 0.0 449.8 327.9 188.9 0.0 0.0 0.0 986.0 935.6 204.7 0.0 404.6 258.6 368.2 0.0 0.0 1367.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 427.7 0.0 0.0 678.1 0.0 0.0 0.0 0.0 922.2 0.0 0.0 94.9 0.0 0.0 2520.3 188.0 0.0 0.0 0.0 217.5 0.0 0.0 0.0 0.0 1001.4 224.2 370.0 0.0 0.0 ATP5MGL "ATP5K2, ATP5L2, dJ222E13.5" ENSG00000249222 "ATP synthase membrane subunit g like" Q7Z4Y8 22 42639803-42640601 "Predicted intracellular proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 1.4;brain: 2.7" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 11.6;Distal tubular cells: 5.9;Extravillous trophoblasts: 7.7;Hofbauer cells: 11.2;Syncytiotrophoblasts: 9.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA044629 Uncertain Uncertain Mitochondria NA NA "Cluster 17: Basophils - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA044629: AB_2679028" "unprognostic (4.53e-2)" "unprognostic (3.46e-2)" "unprognostic (1.20e-2)" "unprognostic (5.67e-2)" "unprognostic (3.01e-2)" "unprognostic (3.36e-2)" "unprognostic (1.31e-2)" "unprognostic (1.70e-2)" "unprognostic (6.74e-2)" "unprognostic (4.40e-2)" "unprognostic (1.26e-1)" "unprognostic (1.51e-1)" "unprognostic (1.51e-1)" "unprognostic (1.17e-1)" "unprognostic (4.17e-1)" "unprognostic (5.12e-2)" "unprognostic (1.85e-3)" 0.1 0.0 0.7 0.0 0.5 1.4 0.0 2.7 1.1 0.0 0.8 0.0 0.1 0.1 0.6 0.1 0.0 0.1 0.1 0.6 1.0 0.1 0.0 0.1 0.3 1.3 0.6 0.1 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.4 0.3 0.0 0.1 0.9 0.1 0.0 0.3 0.1 0.2 0.1 1.3 0.0 0.2 0.0 0.0 0.1 0.0 1.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.2 0.0 0.0 0.1 0.1 0.9 0.2 0.1 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.2 0.2 0.1 0.9 0.1 0.2 0.2 0.1 0.3 0.7 0.5 2.7 1.1 0.6 1.0 1.3 0.6 0.7 0.3 1.3 1.6 1.1 0.0 2.6 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.3 1.1 0.0 0.0 0.0 1.8 0.0 11.6 0.7 0.0 5.9 0.6 0.0 0.8 0.8 0.9 0.0 0.0 0.0 1.1 7.7 1.0 0.0 1.3 2.5 1.2 0.0 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 2.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 9.6 0.8 1.2 0.0 0.0 ATP5PB ATP5F1 ENSG00000116459 "ATP synthase peripheral stalk-membrane subunit b" P24539 1 111448864-111462773 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 135.8;tongue: 131.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 346.5;Distal tubular cells: 461.8;Extravillous trophoblasts: 405.2;Hofbauer cells: 373.0;Proximal tubular cells: 434.6;Syncytiotrophoblasts: 347.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046067, HPA057347" Enhanced Supported Mitochondria "Intracellular and membrane" NA NA 170000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA046067: AB_10960850, HPA057347: AB_2683416" "unprognostic (4.18e-1)" "unprognostic (6.83e-2)" "unprognostic (1.10e-3)" "unprognostic (1.73e-2)" "unprognostic (3.56e-2)" "unprognostic (8.18e-2)" "unprognostic (8.52e-3)" "unprognostic (8.82e-2)" "unprognostic (3.67e-2)" "unprognostic (7.18e-3)" "unprognostic (3.29e-1)" "unprognostic (2.92e-1)" "prognostic favorable (3.26e-9)" "prognostic favorable (8.07e-4)" "unprognostic (1.60e-1)" "unprognostic (2.62e-1)" "unprognostic (1.93e-1)" 19.3 15.7 10.3 11.5 12.5 15.3 18.8 14.5 27.4 17.4 3.9 51.6 28.8 16.6 16.0 26.8 23.9 16.3 109.0 12.1 10.2 40.3 40.2 13.7 24.0 13.4 12.0 19.2 18.5 33.8 7.1 21.6 14.9 22.3 33.6 28.5 29.8 18.7 135.8 15.7 19.0 17.9 9.6 15.2 22.6 15.5 12.8 15.7 31.1 131.0 22.4 21.9 7.4 14.1 55.6 17.6 44.1 36.9 35.6 34.2 34.1 57.0 68.9 67.3 54.7 31.8 29.1 84.9 52.3 45.5 14.3 56.1 69.4 79.5 65.1 61.9 33.2 76.1 21.3 21.5 26.0 98.3 70.8 30.3 40.9 69.3 66.9 17.7 60.0 11.9 78.7 33.6 46.3 35.4 153.3 30.0 34.9 19.2 90.5 41.2 143.6 34.0 54.7 26.0 37.2 13.4 49.4 72.7 55.6 12.6 54.8 46.0 50.6 32.0 49.1 59.4 61.2 41.8 44.5 172.1 70.8 77.6 60.8 3.5 15.4 7.1 14.8 10.0 12.2 12.9 15.1 13.3 16.1 15.2 16.9 10.4 4.8 9.8 9.0 9.2 15.1 44.2 10.3 12.5 14.5 27.4 12.1 10.2 13.4 12.0 14.9 9.6 12.8 14.1 73.2 67.3 83.8 0.0 31.5 0.0 0.0 0.0 0.0 0.0 112.9 155.3 0.0 0.0 57.6 125.0 0.0 346.5 56.4 0.0 461.8 237.3 0.0 132.5 111.0 58.8 0.0 0.0 0.0 196.7 405.2 57.0 0.0 125.4 89.6 82.1 0.0 0.0 373.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 81.8 0.0 0.0 98.8 0.0 0.0 0.0 0.0 162.6 0.0 0.0 9.8 0.0 0.0 434.6 74.3 0.0 0.0 0.0 58.0 0.0 0.0 0.0 0.0 347.7 41.8 208.0 0.0 0.0 ATP5PD "ATP5H, ATP5JD, ATPQ" ENSG00000167863 "ATP synthase peripheral stalk subunit d" O75947 17 75038863-75046985 "Metabolic proteins, Predicted intracellular proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 1142.6;Hofbauer cells: 465.0;Proximal tubular cells: 1059.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042777, HPA048459" Enhanced Supported Mitochondria NA NA 60000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA042777: AB_2678160, HPA048459: AB_2680402" "unprognostic (1.37e-1)" "unprognostic (4.41e-2)" "unprognostic (1.70e-3)" "unprognostic (1.32e-1)" "unprognostic (1.54e-1)" "unprognostic (4.81e-2)" "unprognostic (7.21e-2)" "unprognostic (1.99e-1)" "unprognostic (1.29e-1)" "unprognostic (2.03e-2)" "unprognostic (2.72e-1)" "unprognostic (8.72e-2)" "unprognostic (2.56e-2)" "unprognostic (1.42e-1)" "unprognostic (3.26e-1)" "unprognostic (1.73e-1)" "unprognostic (4.29e-2)" 253.8 271.0 253.5 156.0 260.5 187.2 228.8 270.5 385.7 190.7 282.9 337.1 295.1 170.7 279.9 355.9 173.5 140.1 985.5 261.9 271.1 465.2 454.2 174.0 166.0 264.8 256.9 147.5 222.2 427.1 203.9 174.1 260.8 177.9 323.6 256.0 240.8 200.5 1102.8 264.7 257.4 211.3 260.2 155.0 307.4 93.8 262.3 175.2 263.7 1025.5 221.2 230.3 221.5 261.7 522.8 445.4 335.6 439.8 532.6 647.4 449.1 437.2 571.3 478.5 452.2 351.8 397.1 349.8 282.5 550.2 450.2 462.2 409.0 571.6 637.5 171.6 346.0 359.1 340.2 703.1 524.2 463.5 225.8 555.3 444.8 390.7 552.7 380.9 646.8 268.5 380.1 462.6 595.1 503.3 461.8 515.6 257.1 1185.3 626.9 322.3 970.4 652.3 1007.3 499.7 335.8 368.5 515.5 811.0 730.7 496.9 805.1 463.2 337.4 591.1 413.2 520.0 520.4 369.0 315.5 360.8 530.2 455.4 390.3 410.8 440.7 481.0 274.8 540.9 320.8 364.5 467.5 341.7 509.7 292.8 416.1 388.9 253.0 301.6 458.0 453.6 492.8 495.9 253.5 260.5 270.5 385.7 261.9 271.1 264.8 256.9 260.8 260.2 262.3 261.7 173.8 173.1 156.4 0.0 35.0 0.0 0.0 0.0 0.0 0.0 159.6 234.2 0.0 0.0 102.8 259.3 0.0 384.3 74.0 0.0 1142.6 313.6 0.0 188.2 153.6 70.4 0.0 0.0 0.0 379.5 328.4 82.7 0.0 207.6 88.3 84.6 0.0 0.0 465.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 125.1 0.0 0.0 208.8 0.0 0.0 0.0 0.0 284.3 0.0 0.0 13.8 0.0 0.0 1059.2 101.3 0.0 0.0 0.0 88.3 0.0 0.0 0.0 0.0 336.3 54.4 155.9 0.0 0.0 ATP5PF "ATP5, ATP5A, ATP5J, ATPM, CF6" ENSG00000154723 "ATP synthase peripheral stalk subunit F6" P18859 21 25716503-25735673 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 1595.8" "Cell type enhanced" "Detected in many" "Distal tubular cells: 2375.2;Proximal tubular cells: 1906.2;Syncytiotrophoblasts: 708.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031069 Supported Supported Mitochondria NA NA 820000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 32: U-937 - Innate immune response" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA031069: AB_10603676" "unprognostic (3.52e-2)" "unprognostic (1.33e-1)" "unprognostic (1.46e-1)" "unprognostic (4.57e-2)" "unprognostic (1.14e-1)" "unprognostic (7.87e-2)" "unprognostic (1.43e-1)" "unprognostic (6.32e-2)" "unprognostic (1.48e-1)" "unprognostic (4.87e-2)" "unprognostic (1.77e-1)" "unprognostic (8.83e-2)" "prognostic favorable (2.37e-5)" "unprognostic (1.93e-1)" "unprognostic (9.20e-2)" "unprognostic (1.56e-1)" "unprognostic (2.15e-2)" 274.6 276.3 291.2 136.4 295.4 175.1 205.5 302.5 424.4 156.3 316.1 333.5 276.4 128.8 368.1 258.1 129.9 129.7 1052.1 295.2 306.2 489.5 756.3 110.8 166.4 299.3 297.8 127.2 188.2 458.8 140.4 171.5 295.7 160.1 314.4 249.5 214.6 228.5 1161.7 113.6 250.6 189.8 298.7 111.2 226.9 131.5 299.4 217.5 166.0 1595.8 210.9 194.9 138.4 299.6 355.9 260.0 314.5 351.4 344.8 313.5 389.4 305.8 373.0 305.8 300.8 607.6 274.4 439.3 194.2 312.9 467.8 191.5 441.3 379.2 339.2 373.1 441.1 910.6 520.6 618.4 386.8 673.2 284.5 303.1 471.2 284.0 258.6 399.9 363.0 412.2 582.2 522.9 458.2 416.3 468.6 683.2 562.3 824.0 460.7 358.0 606.5 840.0 669.8 504.6 360.2 394.1 516.5 521.7 493.0 449.4 376.5 590.5 260.6 219.6 266.6 209.3 265.9 501.7 954.7 568.2 341.5 707.8 283.1 444.8 447.0 443.7 293.3 487.1 316.1 475.1 385.5 368.6 531.9 399.7 377.4 370.7 292.3 389.9 505.7 504.0 520.3 661.3 291.2 295.4 302.5 424.4 295.2 306.2 299.3 297.8 295.7 298.7 299.4 299.6 532.1 169.9 179.3 0.0 56.0 0.0 0.0 0.0 0.0 0.0 346.3 468.4 0.0 0.0 105.9 419.3 0.0 652.7 116.4 0.0 2375.2 447.0 0.0 299.2 257.6 150.6 0.0 0.0 0.0 472.5 522.8 135.6 0.0 308.5 109.7 341.2 0.0 0.0 522.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 154.2 0.0 0.0 226.4 0.0 0.0 0.0 0.0 427.1 0.0 0.0 21.4 0.0 0.0 1906.2 142.1 0.0 0.0 0.0 161.4 0.0 0.0 0.0 0.0 708.2 79.2 387.8 0.0 0.0 ATP5PO "ATP5O, ATPO, OSCP" ENSG00000241837 "ATP synthase peripheral stalk subunit OSCP" P48047 21 33903453-33915814 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 1601.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 610.3;Distal tubular cells: 1794.2;Extravillous trophoblasts: 623.2;Hofbauer cells: 627.0;Proximal tubular cells: 1236.8;Syncytiotrophoblasts: 542.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016209, HPA041394" Enhanced Approved Mitochondria NA NA 150000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 7: Non-specific - Mitochondria" Mitochondria "CAB016209: AB_631361, HPA041394: AB_2677450" "unprognostic (2.08e-1)" "unprognostic (4.77e-3)" "unprognostic (3.30e-1)" "unprognostic (6.12e-3)" "unprognostic (1.51e-1)" "unprognostic (1.46e-1)" "unprognostic (1.48e-1)" "unprognostic (2.34e-1)" "unprognostic (8.47e-2)" "unprognostic (1.42e-1)" "unprognostic (3.27e-1)" "unprognostic (1.81e-1)" "prognostic favorable (9.34e-4)" "unprognostic (1.03e-1)" "unprognostic (1.37e-2)" "unprognostic (3.26e-2)" "unprognostic (7.89e-3)" 213.0 181.0 282.7 147.9 289.4 310.6 280.4 306.0 417.7 204.8 325.2 351.9 357.2 169.2 251.1 288.3 216.7 157.9 1114.5 291.2 317.4 458.0 401.8 148.9 243.3 298.2 290.8 273.1 196.7 432.9 108.0 192.2 296.5 158.0 391.9 219.4 236.3 202.0 1063.7 188.4 293.8 217.4 290.9 143.4 304.2 150.3 291.4 281.7 224.4 1601.7 292.9 242.3 161.6 292.4 398.4 187.3 491.1 486.6 340.0 435.1 554.6 218.5 394.4 371.4 361.9 553.5 372.7 531.5 187.2 345.1 355.2 217.5 549.0 764.7 440.6 400.0 544.0 790.3 260.4 513.5 389.7 603.7 260.9 445.8 467.9 358.4 581.9 407.0 522.8 421.2 656.3 665.9 488.5 402.5 461.6 593.0 561.3 992.2 540.1 471.6 490.1 1007.5 1032.8 337.0 404.4 232.1 380.2 559.7 525.7 425.6 562.9 660.5 291.0 236.8 280.6 423.0 252.6 429.1 524.2 559.7 438.2 1046.2 349.3 329.7 561.5 407.8 335.9 596.2 400.9 575.4 439.5 404.8 753.0 487.3 540.9 459.4 136.2 412.6 539.8 445.4 585.3 1077.9 282.7 289.4 306.0 417.7 291.2 317.4 298.2 290.8 296.5 290.9 291.4 292.4 195.8 243.6 191.1 0.0 82.1 0.0 0.0 0.0 0.0 0.0 282.6 476.1 0.0 0.0 121.3 222.5 0.0 610.3 81.3 0.0 1794.2 394.5 0.0 133.0 140.9 87.3 0.0 0.0 0.0 420.2 623.2 109.7 0.0 114.8 114.8 198.9 0.0 0.0 627.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 131.2 0.0 0.0 218.1 0.0 0.0 0.0 0.0 331.9 0.0 0.0 17.8 0.0 0.0 1236.8 102.0 0.0 0.0 0.0 119.0 0.0 0.0 0.0 0.0 542.1 67.4 208.9 0.0 0.0 ATP6V1C2 "ATP6C2, VMA5" ENSG00000143882 "ATPase H+ transporting V1 subunit C2" Q8NEY4 2 10721100-10785110 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 80.3;salivary gland: 103.2;skin 1: 87.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 147.2;Distal tubular cells: 45.0;Enteroendocrine cells: 41.5;Glandular and luminal cells: 73.4;Ionocytes: 93.6;Syncytiotrophoblasts: 169.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "BEWO: 78.4;SK-BR-3: 27.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034734, HPA067305" Approved Uncertain Mitochondria NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA034734: AB_2674305, HPA067305: AB_2732763" "unprognostic (2.29e-1)" "unprognostic (1.86e-1)" "unprognostic (1.15e-2)" "unprognostic (6.55e-3)" "unprognostic (2.69e-2)" "unprognostic (2.20e-2)" "unprognostic (7.03e-3)" "unprognostic (8.53e-2)" "unprognostic (1.29e-1)" "unprognostic (2.11e-2)" "unprognostic (6.77e-2)" "unprognostic (2.73e-2)" "prognostic unfavorable (1.12e-11)" "unprognostic (6.17e-2)" "unprognostic (3.30e-1)" "unprognostic (2.37e-1)" "unprognostic (8.27e-2)" 3.4 4.0 1.4 1.7 2.1 4.3 5.7 0.7 1.4 57.5 0.9 2.4 0.9 4.7 80.3 18.3 2.9 0.9 3.0 1.8 0.8 43.3 6.0 2.8 2.0 0.7 0.8 2.9 3.8 1.2 23.5 36.7 0.6 5.1 2.5 1.6 103.2 6.8 1.0 87.6 2.7 0.2 0.6 4.0 2.4 2.0 0.9 0.5 3.8 0.0 5.0 2.0 19.0 1.6 0.6 0.9 2.4 2.7 0.0 0.0 78.4 1.1 0.0 0.0 0.0 1.5 1.9 1.9 1.3 0.0 1.2 1.2 1.3 0.1 0.1 1.1 2.6 0.9 1.4 2.7 0.0 1.8 1.0 0.0 0.3 0.0 0.0 1.8 0.0 0.6 0.9 3.6 0.0 2.1 0.7 2.9 1.8 1.1 0.8 1.6 1.4 5.5 0.0 1.7 1.9 2.3 0.7 27.2 0.8 10.0 2.4 4.0 0.4 0.9 1.8 1.1 1.1 6.2 2.5 1.1 1.1 1.5 0.8 0.0 0.1 0.1 0.3 0.3 0.2 0.1 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.2 1.4 2.1 0.7 1.4 1.8 0.8 0.7 0.8 0.6 0.6 0.9 1.6 13.6 0.0 2.6 0.3 1.0 0.4 3.7 2.8 1.2 0.0 1.4 1.8 0.9 0.0 6.6 7.3 0.0 147.2 0.8 0.3 45.0 0.1 0.7 31.3 13.4 1.4 41.5 0.0 2.4 0.2 33.0 2.7 1.1 73.4 2.5 0.3 0.0 0.2 13.8 0.0 1.2 0.2 93.6 0.8 0.8 0.4 0.6 0.9 0.0 2.8 0.0 0.0 0.0 0.5 1.3 0.2 0.1 0.0 4.0 1.1 0.0 1.1 4.4 0.0 0.0 0.7 1.2 0.2 1.2 0.6 2.4 169.1 1.0 0.3 0.8 0.4 ATPAF1 "ATP11, Atp11p, FLJ22351" ENSG00000123472 "ATP synthase mitochondrial F1 complex assembly factor 1" Q5TC12 1 46632737-46673867 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 263.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 284.7;Distal tubular cells: 172.1;Early spermatids: 261.4;Late spermatids: 373.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028382, HPA044950" Approved Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 5: NTERA-2 - Transcription" "Cluster 34: Spermatids - Unknown function" Mitochondria "HPA028382: AB_2672574, HPA044950: AB_2679151" "unprognostic (1.34e-1)" "unprognostic (2.97e-3)" "unprognostic (1.18e-2)" "unprognostic (5.96e-2)" "unprognostic (1.20e-1)" "unprognostic (5.97e-2)" "unprognostic (3.53e-1)" "unprognostic (1.72e-2)" "unprognostic (1.70e-2)" "unprognostic (1.19e-2)" "unprognostic (5.15e-2)" "unprognostic (1.05e-1)" "prognostic favorable (5.33e-7)" "unprognostic (1.36e-1)" "unprognostic (6.52e-2)" "unprognostic (2.44e-1)" "unprognostic (2.62e-1)" 66.0 89.9 87.5 23.3 94.4 27.4 30.2 97.1 115.2 30.0 102.8 44.9 35.3 22.5 29.4 30.1 27.3 25.8 221.0 82.9 107.7 97.1 95.3 21.9 27.9 85.8 85.6 28.8 41.2 121.5 43.8 32.3 85.3 32.2 48.1 63.9 48.4 29.0 221.0 20.1 35.2 32.3 80.7 21.6 42.1 41.5 90.6 37.8 37.1 263.4 28.5 26.4 20.2 82.2 57.8 46.1 61.1 54.8 65.1 52.3 51.0 42.2 52.6 62.0 49.7 37.2 24.5 34.1 55.2 53.6 54.9 43.6 97.3 54.7 83.1 75.0 76.7 60.2 54.5 65.0 52.4 60.2 3.4 51.4 64.3 66.5 57.7 49.2 39.3 62.8 28.2 65.4 48.0 52.3 89.3 33.3 96.3 49.8 68.8 38.1 16.5 74.3 71.4 45.2 71.8 53.8 71.4 74.9 114.6 70.0 69.3 83.8 34.4 21.1 52.1 43.1 58.5 80.6 78.9 23.2 34.7 23.0 40.6 0.0 1.6 4.1 2.1 2.8 2.7 1.8 2.2 2.5 1.6 1.2 3.1 1.4 1.3 5.6 1.2 1.2 4.5 1.2 87.5 94.4 97.1 115.2 82.9 107.7 85.8 85.6 85.3 80.7 90.6 82.2 12.6 3.2 18.6 31.0 22.3 9.4 21.2 9.7 27.3 34.0 27.8 19.4 284.7 31.5 13.1 31.3 27.1 64.0 14.5 26.7 172.1 22.1 261.4 15.6 15.4 13.2 19.2 31.3 37.1 20.1 30.0 28.5 29.0 15.9 15.9 40.6 10.4 39.8 39.2 47.1 48.5 38.1 16.2 21.6 12.9 373.7 19.0 16.1 24.9 15.9 14.6 39.2 15.5 28.1 33.7 11.3 18.0 26.7 36.3 15.2 30.2 119.1 10.2 29.2 26.3 25.1 28.9 45.2 40.4 34.3 13.5 46.9 19.2 55.1 42.2 21.9 BAD "BBC2, BCL2L8" ENSG00000002330 "BCL2 associated agonist of cell death" Q92934 11 64269830-64284704 "Cancer-related genes, Predicted intracellular proteins, RAS pathway related proteins" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004205, HPA028185, HPA062105" Approved Enhanced Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "CAB004205: AB_626717, HPA028185: AB_10603445, HPA062105: AB_2684684" "unprognostic (1.47e-1)" "unprognostic (3.08e-2)" "unprognostic (1.17e-1)" "unprognostic (8.24e-3)" "unprognostic (2.60e-1)" "unprognostic (6.73e-2)" "unprognostic (1.24e-3)" "unprognostic (1.07e-1)" "unprognostic (1.99e-1)" "unprognostic (1.10e-1)" "unprognostic (1.36e-1)" "unprognostic (1.14e-1)" "unprognostic (8.26e-2)" "unprognostic (9.04e-2)" "unprognostic (2.17e-1)" "unprognostic (1.48e-1)" "unprognostic (7.95e-2)" 60.8 85.1 94.0 13.2 91.1 23.3 58.8 89.0 133.1 64.9 86.6 81.7 26.5 64.8 12.7 72.9 58.8 15.5 118.0 93.1 87.8 87.6 96.1 58.7 14.7 93.4 92.7 55.2 53.7 35.6 55.3 21.7 89.4 79.7 15.1 17.2 57.7 27.6 50.7 70.6 44.7 14.0 89.9 45.0 87.1 55.1 98.9 17.2 75.8 15.1 12.4 65.9 57.7 92.7 95.0 85.1 25.2 38.3 30.0 36.4 36.9 38.2 45.9 60.0 47.5 54.8 53.1 19.5 67.7 37.4 46.9 49.9 16.8 62.7 11.9 77.6 58.7 24.9 81.4 26.1 45.9 20.7 45.0 35.3 53.7 45.8 28.3 45.9 37.5 44.1 10.1 42.9 26.6 94.7 49.8 49.7 9.8 27.7 109.6 46.7 13.8 57.9 36.8 44.3 51.2 67.1 39.2 46.8 49.9 9.6 70.5 32.0 30.3 72.8 48.1 112.8 43.8 79.6 64.0 21.3 59.2 15.6 40.6 88.0 69.7 102.3 52.9 56.7 54.7 58.6 55.4 51.9 50.5 57.5 39.8 40.9 92.4 59.5 55.3 94.0 71.8 51.4 94.0 91.1 89.0 133.1 93.1 87.8 93.4 92.7 89.4 89.9 98.9 92.7 56.3 32.1 45.1 7.8 32.9 103.1 54.1 170.2 51.2 67.7 76.7 74.8 51.6 70.1 66.4 53.3 18.8 162.5 32.4 214.4 137.0 101.2 43.5 71.5 64.8 56.8 104.1 69.2 10.4 109.9 197.8 75.3 53.0 45.4 24.1 58.2 62.4 51.0 73.8 47.1 7.5 141.8 89.5 24.1 72.6 93.3 74.3 32.9 110.3 2.8 52.4 95.9 36.0 4.0 8.9 120.7 210.0 85.4 33.2 62.1 138.1 152.8 83.2 52.0 59.2 36.2 72.6 69.5 25.0 57.7 119.1 255.0 36.0 57.8 117.1 63.4 BCKDK ENSG00000103507 "Branched chain keto acid dehydrogenase kinase" O14874 16 31106107-31112791 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Autism, Autism spectrum disorder, Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 95.9;granulocytes: 89.7;monocytes: 115.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017995, HPA056067" Supported Supported Mitochondria NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 4: Macrophages - Innate immune response" Mitochondria "HPA017995: AB_1845309, HPA056067: AB_2683024" "unprognostic (1.37e-1)" "unprognostic (2.57e-1)" "unprognostic (6.94e-2)" "unprognostic (5.20e-2)" "unprognostic (5.39e-2)" "unprognostic (3.61e-2)" "unprognostic (1.01e-1)" "unprognostic (5.47e-2)" "unprognostic (1.60e-1)" "unprognostic (1.90e-1)" "unprognostic (1.35e-1)" "unprognostic (3.24e-2)" "unprognostic (2.66e-3)" "unprognostic (4.85e-2)" "unprognostic (3.93e-2)" "unprognostic (1.00e-1)" "unprognostic (4.97e-2)" 32.3 56.4 18.4 19.2 18.6 14.5 29.0 17.4 23.8 25.1 18.0 31.4 16.0 27.7 16.7 29.4 24.8 17.9 78.6 18.8 17.8 43.8 76.4 21.7 15.6 20.6 20.7 27.5 70.5 22.9 16.4 15.3 19.3 29.3 12.5 6.3 47.0 21.8 81.3 45.4 24.1 19.5 17.1 30.2 42.0 17.4 18.5 9.8 22.4 69.7 13.6 30.2 24.6 17.5 47.5 49.1 27.1 41.8 32.8 32.5 31.1 40.4 46.3 57.3 55.9 32.1 29.1 41.5 58.9 47.5 28.0 31.4 19.3 65.6 36.5 34.4 60.1 45.2 32.6 59.5 57.5 23.5 41.9 48.3 26.2 49.2 40.6 52.6 62.4 31.1 23.4 39.4 87.7 75.8 22.9 32.4 23.0 20.5 39.1 45.8 39.6 78.8 44.3 30.1 42.1 38.7 31.3 72.4 24.6 22.9 44.5 24.6 41.1 44.2 26.1 45.8 32.2 44.5 15.7 15.1 50.3 33.7 42.6 58.1 115.0 85.2 17.7 97.6 17.2 22.8 16.5 13.9 95.9 19.0 13.6 16.1 89.7 22.8 71.2 19.3 24.5 53.1 18.4 18.6 17.4 23.8 18.8 17.8 20.6 20.7 19.3 17.1 18.5 17.5 27.2 19.2 18.1 5.9 20.0 18.5 24.6 61.0 22.2 11.6 30.9 27.6 39.1 25.8 28.5 20.2 0.0 55.4 9.0 31.5 80.3 68.6 2.5 14.6 24.3 29.2 19.9 16.4 5.1 78.0 71.1 24.9 25.5 20.0 33.0 35.4 25.4 43.8 93.0 11.8 4.4 22.3 42.7 44.5 50.3 7.8 20.8 53.1 12.4 1.9 79.3 22.6 9.2 4.5 4.5 54.8 48.4 25.6 51.7 30.9 66.9 95.2 19.6 9.8 46.0 18.4 33.2 25.8 14.1 25.7 27.4 69.4 12.1 45.5 26.0 27.0 BCL2L1 "Bcl-X, bcl-xL, bcl-xS, BCL2L, BCLX, PPP1R52" ENSG00000171552 "BCL2 like 1" Q07817 20 31664452-31723989 "Cancer-related genes, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Apoptosis, Endocytosis" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 160.0;Pancreatic endocrine cells: 187.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035734, CAB072801" Approved Approved Mitochondria NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 39: CACO-2 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" Mitochondria "CAB072801: , HPA035734: AB_2674757" "unprognostic (2.29e-1)" "unprognostic (5.40e-3)" "unprognostic (1.78e-2)" "prognostic unfavorable (9.10e-4)" "unprognostic (1.37e-1)" "unprognostic (1.09e-1)" "unprognostic (5.04e-2)" "unprognostic (7.82e-3)" "prognostic favorable (9.57e-4)" "unprognostic (1.67e-1)" "prognostic unfavorable (5.87e-4)" "unprognostic (1.06e-1)" "prognostic favorable (8.89e-5)" "unprognostic (9.67e-2)" "unprognostic (3.03e-2)" "unprognostic (2.02e-2)" "unprognostic (3.32e-2)" 80.3 46.9 46.3 26.1 53.7 99.0 71.0 46.7 54.5 46.5 88.2 42.4 49.4 39.2 11.9 77.8 42.7 51.7 77.9 42.2 48.2 95.7 85.2 95.1 25.8 49.5 49.4 23.1 54.7 30.4 49.8 42.0 51.1 52.0 26.2 41.0 70.6 25.2 55.4 65.7 48.9 25.0 41.3 53.4 66.6 46.2 54.4 111.5 51.4 38.8 28.9 42.8 54.7 59.7 327.0 188.4 30.7 32.4 167.8 123.1 101.0 73.8 113.2 69.6 66.4 429.2 150.9 48.2 176.7 108.4 140.7 105.8 42.9 216.7 46.2 55.1 8.6 231.3 34.4 231.6 123.0 19.6 137.7 90.7 77.4 89.4 194.0 102.4 106.0 81.6 150.0 34.5 238.7 94.3 73.9 20.6 45.4 150.8 153.2 43.5 92.9 164.3 249.3 83.4 85.4 38.4 89.3 92.6 42.4 57.2 180.5 26.3 154.1 90.0 109.1 36.8 139.4 22.7 150.7 37.9 143.5 99.5 59.5 28.6 11.0 25.6 39.9 11.7 30.9 4.8 17.1 26.8 10.4 6.0 7.7 18.6 12.5 19.8 13.4 7.0 21.8 28.2 46.3 53.7 46.7 54.5 42.2 48.2 49.5 49.4 51.1 41.3 54.4 59.7 41.6 16.0 9.2 22.5 10.1 18.4 70.2 40.8 26.7 21.9 25.5 15.4 9.7 91.5 36.3 38.6 45.9 27.1 13.7 41.7 86.1 92.2 10.2 71.4 14.6 35.8 24.7 160.0 21.8 65.9 11.3 15.5 37.2 58.2 12.7 10.6 36.4 40.8 38.2 28.6 19.5 26.0 69.2 22.1 13.3 4.6 19.0 27.6 17.8 49.6 76.9 24.1 54.6 13.6 55.6 187.7 22.4 42.9 38.0 102.9 54.6 76.5 76.4 33.7 46.0 14.9 42.7 31.0 15.1 13.6 9.8 18.9 24.9 13.6 19.6 143.0 BCL2L11 "BIM, BimEL, BimL, BimS, BOD" ENSG00000153094 "BCL2 like 11" O43521 2 111119378-111168445 "Predicted intracellular proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 118.3;Plasma cells: 137.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-266/70: 91.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026332, CAB079899" Approved Supported Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 29: U-266 - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Mitochondria "CAB026332: AB_566386, CAB079899: AB_10981505" "unprognostic (1.43e-1)" "unprognostic (9.46e-3)" "unprognostic (1.88e-1)" "unprognostic (1.50e-2)" "unprognostic (1.20e-1)" "unprognostic (3.08e-3)" "unprognostic (1.05e-1)" "unprognostic (5.63e-2)" "unprognostic (2.39e-1)" "unprognostic (3.43e-2)" "unprognostic (1.32e-1)" "unprognostic (1.11e-1)" "unprognostic (1.00e-1)" "unprognostic (2.55e-2)" "unprognostic (9.71e-3)" "unprognostic (8.15e-3)" "unprognostic (7.86e-2)" 8.1 7.4 4.2 16.4 5.0 38.8 12.5 3.7 3.7 7.2 4.6 11.0 7.2 6.5 4.9 9.8 7.0 8.8 5.7 3.0 3.9 10.7 14.3 8.5 24.2 4.3 4.0 10.3 10.3 18.8 9.4 6.0 4.5 7.8 11.9 12.1 10.1 7.1 12.3 5.8 11.7 4.8 3.9 16.3 7.0 8.1 4.4 18.9 16.6 7.3 23.0 8.9 8.2 6.7 8.0 2.4 10.8 10.4 9.1 4.7 29.1 1.2 2.3 3.3 3.3 6.6 24.9 32.0 6.5 1.2 18.9 9.5 10.0 3.9 2.0 24.9 18.2 39.7 8.1 10.5 3.9 14.6 8.8 4.8 10.5 3.7 3.8 7.0 4.6 14.2 20.8 46.6 0.7 5.2 15.3 14.7 13.2 6.3 7.5 19.5 10.3 40.7 4.5 13.0 9.3 24.0 11.0 14.5 8.3 7.1 5.0 31.2 1.9 1.7 11.4 3.7 4.3 91.2 19.5 45.3 2.7 10.1 1.5 5.2 3.7 1.8 1.7 2.6 1.8 3.3 2.3 1.9 1.9 1.9 1.5 1.5 5.2 1.7 5.7 0.4 5.9 1.5 4.2 5.0 3.7 3.7 3.0 3.9 4.3 4.0 4.5 3.9 4.4 6.7 33.9 3.2 9.9 2.9 61.3 17.5 18.2 7.0 34.7 7.4 19.5 29.2 19.3 12.8 10.3 9.2 10.4 4.6 43.9 37.6 13.7 9.7 118.3 36.6 10.8 18.0 21.5 26.5 2.2 6.5 7.8 11.6 8.6 54.7 11.4 5.9 14.6 11.3 10.9 0.0 4.8 15.2 12.2 26.8 52.6 39.2 5.9 34.8 23.2 6.5 41.0 12.1 5.2 3.0 5.3 8.8 16.4 3.8 137.9 15.9 16.6 6.4 15.2 21.1 0.0 11.8 11.9 7.3 17.7 66.1 10.9 5.7 41.0 2.5 12.3 16.0 BCL2L13 "BCL-RAMBO, MIL1" ENSG00000099968 "BCL2 like 13" Q9BXK5 22 17628855-17730855 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 59.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 180.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002052, HPA030994, HPA050377" Uncertain Enhanced Mitochondria NA NA 100000 "Cluster 7: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 56: Bipolar cells - Visual perception" Mitochondria "CAB002052: AB_563431, HPA030994: AB_10795024, HPA050377: AB_2681107" "unprognostic (1.59e-1)" "unprognostic (8.17e-2)" "unprognostic (2.18e-3)" "unprognostic (1.86e-1)" "unprognostic (6.27e-2)" "unprognostic (2.69e-2)" "unprognostic (3.38e-1)" "unprognostic (4.97e-2)" "unprognostic (5.04e-2)" "unprognostic (9.46e-2)" "unprognostic (1.45e-2)" "unprognostic (8.21e-2)" "prognostic favorable (1.96e-8)" "unprognostic (3.20e-1)" "unprognostic (1.07e-1)" "unprognostic (4.27e-1)" "unprognostic (2.81e-1)" 13.4 13.3 8.7 5.7 11.6 10.8 11.5 8.4 12.8 7.7 1.4 10.0 6.0 7.9 8.8 12.3 7.4 6.8 19.7 9.4 9.9 14.0 16.4 8.4 7.6 11.6 13.7 7.5 11.8 14.8 7.8 9.2 12.1 8.2 10.3 43.8 10.0 6.8 59.6 14.1 7.8 7.6 9.2 6.4 9.5 10.7 9.7 9.2 9.6 40.5 8.7 10.3 8.7 9.4 16.2 6.1 10.6 11.1 19.6 18.8 17.2 11.4 21.3 17.1 19.8 8.3 11.7 14.6 7.5 15.4 13.9 21.3 12.6 18.4 20.9 12.2 12.3 14.5 7.5 6.1 22.3 21.3 10.0 14.5 21.1 14.0 40.1 24.2 14.7 11.3 34.5 15.2 18.9 11.6 11.7 8.9 10.7 26.8 9.7 10.9 20.7 5.3 20.1 12.4 15.6 11.5 16.4 15.6 31.0 38.0 11.9 18.0 17.2 9.9 5.0 15.3 10.5 11.9 10.5 14.7 14.9 16.1 16.4 5.1 9.5 2.3 2.3 8.0 2.8 3.1 3.1 2.7 5.4 3.2 2.8 2.3 3.6 6.5 6.4 2.9 4.5 4.7 8.7 11.6 8.4 12.8 9.4 9.9 11.6 13.7 12.1 9.2 9.7 9.4 18.7 22.4 16.7 32.3 21.5 24.6 33.6 22.7 30.1 180.5 21.8 22.4 42.7 12.8 25.3 18.4 12.5 48.5 19.7 31.7 52.8 29.1 34.8 17.7 16.0 17.5 23.4 19.8 41.9 31.6 35.0 20.0 13.3 23.5 8.8 19.7 15.7 36.0 26.0 48.8 38.1 25.4 18.3 30.8 19.8 15.5 14.0 26.3 16.0 27.2 54.7 57.9 12.3 27.6 45.4 36.4 17.8 15.4 15.4 40.3 32.6 44.4 19.6 35.2 0.0 21.3 15.6 33.1 22.6 32.1 27.1 95.9 19.3 22.9 24.0 43.1 BDH1 "BDH, SDR9C1" ENSG00000161267 "3-hydroxybutyrate dehydrogenase 1" Q02338 3 197509783-197573323 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Allosteric enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 324.0" "Cell type enhanced" "Detected in many" "Hepatocytes: 112.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 44.2;U-937: 75.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA030947, HPA058709" Enhanced Approved Mitochondria NA NA "Cluster 30: Non-specific - Translation" "Cluster 85: Liver - Metabolism" "Cluster 32: U-937 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA030947: AB_10669548, HPA058709: AB_2683797" "unprognostic (2.72e-2)" "prognostic favorable (1.09e-4)" "unprognostic (1.13e-1)" "unprognostic (3.93e-1)" "unprognostic (3.35e-2)" "unprognostic (1.07e-1)" "prognostic favorable (9.86e-7)" "unprognostic (2.08e-1)" "unprognostic (3.85e-2)" "unprognostic (4.53e-2)" "unprognostic (5.17e-3)" "unprognostic (5.85e-3)" "prognostic favorable (7.12e-8)" "unprognostic (5.62e-2)" "unprognostic (1.74e-1)" "unprognostic (6.22e-2)" "unprognostic (1.02e-1)" 9.6 6.8 14.4 4.1 17.9 7.3 9.7 18.4 19.8 6.8 30.8 45.1 17.4 6.3 3.9 48.0 9.7 3.8 52.4 16.5 14.3 19.2 324.0 5.2 3.9 14.3 13.8 8.2 7.0 15.5 12.6 0.3 14.4 16.2 19.8 9.3 25.3 4.1 21.5 30.4 28.1 2.2 12.9 7.9 16.6 4.5 16.3 6.1 17.7 22.8 7.1 9.9 14.7 14.2 23.7 2.9 1.2 11.3 1.9 0.1 0.0 2.8 2.2 11.4 6.3 20.5 7.5 0.2 33.0 0.7 0.9 10.3 10.0 5.4 4.2 0.3 0.0 12.0 8.3 7.0 8.3 27.0 12.3 3.4 6.0 4.4 9.4 1.2 2.8 13.7 0.0 8.4 0.2 40.9 20.5 18.8 8.2 44.2 4.2 19.6 4.1 31.5 12.3 9.9 20.1 8.8 8.2 1.1 4.5 0.5 26.3 22.7 0.3 0.7 3.9 0.1 21.6 10.4 20.5 0.3 0.7 75.8 1.5 2.9 1.3 0.6 4.6 0.2 6.4 5.1 5.1 4.2 3.5 4.6 7.6 4.7 0.0 4.5 0.2 3.8 3.7 3.4 14.4 17.9 18.4 19.8 16.5 14.3 14.3 13.8 14.4 12.9 16.3 14.2 0.4 3.2 9.4 27.7 7.0 9.3 8.5 10.0 16.5 21.3 20.3 14.7 36.7 17.2 13.8 12.9 20.9 2.0 7.1 68.9 52.8 6.6 9.5 34.1 3.6 2.2 27.2 6.7 60.5 5.6 5.1 2.8 17.3 16.5 1.3 6.6 5.0 112.3 8.9 18.5 58.0 43.2 10.2 5.4 8.5 13.9 5.6 3.5 16.0 8.4 1.0 17.5 11.3 27.2 12.5 3.0 36.4 4.1 5.4 6.5 62.8 30.2 48.0 33.6 0.0 2.4 3.7 16.8 4.9 36.3 10.9 1.9 8.5 10.0 68.7 13.1 BMP6 "VGR, VGR1" ENSG00000153162 "Bone morphogenetic protein 6" P22004 6 7726099-7881728 "Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 23.0;Hepatic stellate cells: 16.8;Inhibitory neurons: 22.8;Microglial cells: 74.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 11 "granulocytes: 1.1" "Cell line enhanced" "Detected in many" "EFO-21: 37.0;HUVEC TERT2: 149.6;Karpas-707: 81.6;SiHa: 70.0;TIME: 74.3;U-266/84: 41.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002773, HPA062683" Approved Approved Mitochondria "Secreted to blood" No No 4970000 46000 "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "CAB002773: , HPA062683: AB_2684832" "prognostic favorable (6.45e-4)" "unprognostic (2.99e-1)" "unprognostic (4.20e-1)" "unprognostic (6.71e-2)" "unprognostic (2.44e-1)" "unprognostic (7.27e-2)" "unprognostic (4.66e-2)" "unprognostic (1.29e-1)" "unprognostic (1.26e-1)" "unprognostic (6.94e-2)" "unprognostic (2.80e-2)" "unprognostic (2.02e-1)" "unprognostic (1.26e-1)" "unprognostic (1.82e-2)" "unprognostic (8.29e-2)" "unprognostic (2.95e-1)" "unprognostic (2.29e-3)" 16.5 3.1 5.1 2.2 5.9 0.4 12.7 3.9 6.2 3.2 7.8 3.7 3.0 3.5 0.6 2.0 2.4 2.1 5.1 3.9 3.7 17.8 1.9 9.1 1.5 4.9 4.5 8.2 0.6 0.6 4.6 18.1 4.7 2.8 2.7 0.1 2.3 2.6 3.1 3.5 3.0 2.3 4.8 4.6 4.7 2.2 5.7 0.9 1.5 1.3 2.4 3.3 3.0 4.1 0.9 2.4 0.3 0.0 0.4 0.3 0.0 2.0 0.1 0.0 0.0 0.0 0.0 0.0 37.0 1.1 1.6 0.5 1.1 0.2 0.0 0.0 5.7 15.9 21.8 1.4 0.8 1.1 16.7 0.0 0.0 0.7 2.4 9.6 149.6 0.0 0.0 81.6 0.0 0.3 0.0 0.0 0.8 0.5 12.0 0.6 0.0 15.3 0.5 0.0 12.3 0.0 70.0 0.0 0.0 9.3 0.0 0.0 74.3 0.0 4.7 0.5 2.6 11.3 41.3 0.1 2.3 0.0 1.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.5 5.1 5.9 3.9 6.2 3.9 3.7 4.9 4.5 4.7 4.8 5.7 4.1 23.0 0.0 0.5 1.6 1.1 0.3 0.0 0.0 0.0 0.0 0.1 0.1 3.5 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.8 0.2 8.9 0.0 0.0 7.8 0.0 0.1 2.0 0.0 2.0 0.0 1.5 16.8 0.6 0.3 0.0 22.8 0.0 0.0 0.8 2.1 4.2 0.0 1.5 1.8 74.0 0.7 0.0 0.0 0.0 0.3 0.1 0.0 0.0 6.8 0.3 0.0 0.0 0.3 0.0 0.0 4.7 0.4 0.1 1.3 0.1 0.1 0.3 0.4 0.4 0.0 0.0 BPHL "Bph-rp, MCNAA, VACVase" ENSG00000137274 "Biphenyl hydrolase like" Q86WA6 6 3118374-3153578 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 110.4;liver: 84.8" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 99.7;Proximal tubular cells: 336.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036752, HPA036753" Enhanced Approved Mitochondria NA NA 14000 "Cluster 44: Non-specific - Transcription" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA036752: AB_10673662, HPA036753: AB_2675291" "unprognostic (2.93e-1)" "unprognostic (1.29e-1)" "unprognostic (8.88e-2)" "unprognostic (1.11e-1)" "unprognostic (3.72e-3)" "unprognostic (1.84e-1)" "unprognostic (8.65e-2)" "unprognostic (3.14e-2)" "unprognostic (1.94e-1)" "prognostic favorable (5.97e-4)" "unprognostic (4.59e-2)" "unprognostic (9.46e-3)" "prognostic favorable (5.16e-7)" "unprognostic (1.60e-2)" "unprognostic (1.51e-2)" "unprognostic (6.98e-2)" "unprognostic (5.20e-2)" 24.1 15.3 9.4 3.9 9.8 3.5 11.2 9.5 14.5 9.3 11.8 10.6 33.8 7.0 28.8 13.2 11.1 8.9 11.6 10.1 10.8 110.4 84.8 5.2 4.4 9.8 10.2 6.5 11.5 10.8 12.7 5.0 10.7 6.8 9.4 4.2 11.3 4.7 15.5 11.2 32.8 5.8 8.6 3.9 10.0 5.0 9.8 4.8 5.5 12.5 5.9 9.0 9.1 10.8 12.0 13.8 26.8 30.6 22.5 16.2 10.2 7.1 8.7 8.6 11.4 12.4 15.3 18.6 19.7 9.2 21.4 22.1 11.7 8.0 7.6 24.8 10.5 2.7 5.4 21.8 7.9 6.3 1.8 16.9 14.1 6.3 6.0 17.7 15.5 18.8 7.2 3.0 19.9 18.2 14.8 8.3 22.5 21.1 21.9 16.1 17.7 27.9 19.7 30.3 31.7 23.3 13.2 9.0 58.4 39.4 25.6 2.2 7.7 12.5 3.4 13.1 4.9 8.6 27.8 20.4 3.5 4.0 18.4 13.6 9.8 0.0 8.2 12.9 10.9 17.5 9.7 8.4 15.3 12.8 9.1 12.7 0.6 14.6 7.8 8.4 5.4 7.5 9.4 9.8 9.5 14.5 10.1 10.8 9.8 10.2 10.7 8.6 9.8 10.8 15.9 6.4 9.3 11.1 8.2 8.9 8.6 26.0 10.8 11.1 15.1 19.0 4.8 31.5 19.3 16.5 20.9 28.6 5.6 13.6 70.5 28.1 0.5 13.6 14.0 9.1 16.1 6.9 9.3 13.5 32.2 12.2 11.2 8.2 2.5 31.8 6.1 70.9 23.7 16.8 12.8 14.9 38.7 2.2 8.3 1.6 14.9 8.0 32.0 10.3 13.9 12.2 7.2 9.0 4.7 19.6 14.8 13.9 4.5 8.4 99.7 336.3 38.2 6.9 6.6 19.0 12.5 6.8 20.6 13.9 9.2 14.0 7.6 32.9 19.0 8.1 BTN2A2 "BT2.2, BTF2, BTN2.2" ENSG00000124508 "Butyrophilin subfamily 2 member A2" Q8WVV5 6 26383096-26394874 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 30.3;Plasma cells: 30.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 72.8;U-266/70: 58.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA051504 Uncertain Approved Mitochondria NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 57: B-cells - Immune response" Mitochondria "HPA051504: AB_2681510" "prognostic favorable (1.01e-4)" "unprognostic (4.93e-3)" "unprognostic (1.37e-2)" "unprognostic (6.78e-2)" "unprognostic (9.26e-2)" "unprognostic (2.01e-2)" "unprognostic (1.78e-1)" "unprognostic (8.04e-3)" "unprognostic (1.01e-1)" "unprognostic (1.22e-2)" "unprognostic (6.67e-2)" "unprognostic (1.93e-1)" "unprognostic (1.73e-2)" "unprognostic (3.45e-1)" "unprognostic (6.54e-2)" "unprognostic (2.90e-1)" "unprognostic (1.36e-3)" 7.2 13.5 5.4 21.9 6.9 4.3 8.7 14.4 6.0 7.9 21.2 8.0 7.2 10.2 7.5 5.1 8.4 8.5 4.9 6.8 5.9 7.5 6.1 16.2 32.1 7.5 6.9 10.4 5.2 17.5 5.7 4.0 7.8 8.3 10.5 2.9 12.1 6.8 2.8 11.0 11.3 10.9 6.5 21.8 10.4 6.1 6.2 15.2 7.5 4.2 36.6 8.2 6.9 6.9 10.6 6.6 13.2 14.2 4.4 6.8 0.9 11.4 29.7 17.4 30.0 4.2 4.1 9.6 12.1 20.5 14.1 9.5 10.7 8.7 23.1 29.9 17.9 15.0 13.2 8.4 9.1 3.4 5.1 14.5 2.7 33.5 11.3 20.7 16.3 18.5 12.3 72.8 7.9 4.6 12.1 4.4 5.0 0.4 6.6 28.1 18.7 29.8 12.7 5.9 12.6 17.6 7.4 2.8 31.1 7.5 13.5 6.6 19.5 6.4 7.3 5.6 17.7 58.9 38.8 16.9 6.4 13.4 16.3 2.1 13.7 2.4 6.1 14.6 5.8 24.1 5.0 5.7 23.9 29.4 4.1 5.1 12.4 8.7 6.3 9.7 10.3 7.9 5.4 6.9 14.4 6.0 6.8 5.9 7.5 6.9 7.8 6.5 6.2 6.9 8.1 9.6 12.6 0.0 30.3 3.8 7.3 6.5 6.2 0.6 5.2 5.1 2.5 2.8 8.5 3.7 0.0 2.3 15.0 0.6 0.0 8.6 0.4 8.8 4.5 13.1 1.8 3.6 0.0 5.6 0.8 5.0 3.6 7.5 19.6 9.6 6.1 3.8 8.4 0.0 0.0 7.8 12.2 16.0 24.2 0.6 6.5 17.1 7.2 0.0 15.4 14.3 7.2 0.0 0.0 8.3 0.8 4.9 30.7 6.4 2.6 2.3 10.2 0.7 0.0 5.0 4.4 0.3 1.5 4.5 4.5 1.0 10.0 10.6 2.1 4.2 C10orf82 "Em:AC016825.4, MGC33547" ENSG00000165863 "Chromosome 10 open reading frame 82" Q8WW14 10 116663696-116670264 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "testis: 84.5" "Group enriched" "Detected in some" 113 "Early spermatids: 1053.9;Late spermatids: 1926.7" "Cancer enhanced" "Detected in many" "breast cancer: 2.4" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 103 "basophil: 10.2" "Lineage enriched" "Detected in single" 103 "granulocytes: 10.2" "Cell line enhanced" "Detected in some" "BEWO: 1.2;Hep G2: 2.8;NTERA-2: 1.4;SuSa: 2.5;T-47d: 3.5" "Not detected" "Not detected" HPA043022 Approved Mitochondria Yes NA "Cluster 46: Basophils - DNA binding" "Cluster 83: Testis - Spermatogenesis" "Cluster 6: T47d - Mammary gland" "Cluster 34: Spermatids - Unknown function" Mitochondria "HPA043022: " "unprognostic (9.98e-2)" "unprognostic (2.09e-2)" "unprognostic (8.41e-2)" "unprognostic (2.11e-1)" "unprognostic (1.63e-2)" "unprognostic (9.52e-2)" "unprognostic (3.46e-3)" "unprognostic (3.48e-1)" "unprognostic (6.15e-2)" "unprognostic (1.50e-2)" "unprognostic (8.00e-2)" "unprognostic (1.47e-3)" "unprognostic (2.61e-2)" "unprognostic (1.94e-2)" "unprognostic (1.73e-1)" "unprognostic (1.07e-1)" 0.3 1.7 0.3 0.2 0.2 0.0 0.9 0.1 0.4 0.4 0.0 0.9 0.1 0.0 0.2 0.3 0.2 0.1 0.4 0.2 0.8 1.2 0.0 0.0 0.0 0.3 0.5 3.6 1.1 0.0 1.0 0.0 0.4 0.9 0.2 0.1 0.2 0.7 0.0 0.2 0.4 0.0 0.2 0.1 0.4 84.5 0.9 0.0 1.6 0.1 0.0 0.3 0.6 0.2 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.4 0.2 0.8 0.3 0.5 0.4 0.2 0.9 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.4 0.0 0.0 0.0 1.1 1.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1053.9 0.3 0.2 0.5 1.2 0.0 0.5 0.2 0.1 0.1 0.0 0.7 0.0 5.6 0.0 0.0 0.1 0.0 1.8 1.1 0.0 0.0 0.0 1926.7 9.0 0.6 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 5.3 0.0 0.7 0.1 0.1 0.0 0.0 13.1 0.4 0.2 10.5 8.0 0.0 0.0 0.0 0.1 8.0 1.2 0.3 C18orf63 DKFZP781G0119 ENSG00000206043 "Chromosome 18 open reading frame 63" Q68DL7 18 74315839-74359189 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 43 "testis: 9.8" "Cell type enriched" "Detected in some" 10 "Spermatocytes: 83.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA042233 Approved Mitochondria NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Mitochondria "HPA042233: AB_10960843" "unprognostic (1.40e-1)" "unprognostic (1.43e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 83.7 7.9 0.0 0.0 0.0 0.0 0.1 0.1 0.0 C1orf112 FLJ10706 ENSG00000000460 "Chromosome 1 open reading frame 112" Q9NSG2 1 169662007-169854080 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 13.5" "Cell type enhanced" "Detected in many" "Microglial cells: 30.0;Spermatocytes: 37.1;Spermatogonia: 20.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023778, HPA024451" Uncertain Approved Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Mitochondria "HPA023778: AB_1848665, HPA024451: AB_1848667" "unprognostic (4.97e-2)" "unprognostic (1.46e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (9.56e-5)" "unprognostic (1.33e-1)" "unprognostic (9.40e-2)" "unprognostic (2.50e-3)" "unprognostic (2.09e-1)" "unprognostic (9.11e-3)" "unprognostic (8.79e-2)" "unprognostic (3.47e-3)" "unprognostic (5.97e-2)" "unprognostic (1.65e-8)" "unprognostic (1.76e-1)" "unprognostic (2.81e-2)" "unprognostic (6.17e-2)" "unprognostic (2.63e-1)" 1.8 1.2 0.6 3.3 0.9 9.0 2.9 1.7 0.8 2.3 0.5 2.6 1.2 2.9 1.0 2.0 1.5 1.4 1.0 0.5 0.4 1.1 2.6 1.7 6.3 1.0 0.6 2.2 1.5 13.5 1.0 3.4 0.8 1.8 4.1 5.4 1.5 2.0 0.9 2.4 1.8 2.7 0.7 2.8 1.9 10.3 0.9 11.6 1.7 1.5 7.9 3.1 1.7 1.5 32.7 17.5 21.9 11.3 3.5 4.8 32.2 21.1 10.7 30.0 30.6 19.1 27.7 29.0 9.3 7.0 10.7 26.0 27.6 14.7 34.3 16.9 16.5 27.1 23.0 14.1 1.2 35.8 11.3 1.5 1.9 22.5 5.3 3.5 12.8 16.8 44.9 48.0 24.8 7.9 31.5 10.3 28.8 22.9 12.1 23.3 24.7 19.5 4.0 16.1 16.2 16.9 13.4 22.1 6.9 20.6 21.0 18.3 9.5 24.1 19.1 17.8 28.9 12.9 20.9 30.6 9.0 26.4 24.1 2.2 0.8 1.0 0.6 1.9 0.4 1.4 0.6 0.6 1.2 1.4 0.3 0.5 0.1 2.1 2.3 0.4 0.7 0.6 0.6 0.9 1.7 0.8 0.5 0.4 1.0 0.6 0.8 0.7 0.9 1.5 1.2 0.0 3.3 4.2 4.0 1.8 2.7 2.6 1.2 4.1 1.7 1.8 0.5 0.0 1.5 0.0 6.2 9.1 1.6 1.9 0.0 2.7 8.7 0.9 2.1 2.2 0.0 3.4 9.9 3.4 9.1 2.5 2.6 1.2 4.5 9.8 2.9 3.8 6.2 1.7 9.6 1.2 6.1 3.5 2.1 4.1 2.1 3.0 3.6 30.0 1.3 2.4 0.0 13.0 13.2 3.0 0.3 3.8 5.5 1.0 0.8 0.7 2.0 6.6 6.6 1.4 2.6 37.1 20.3 2.8 1.0 3.8 3.3 2.2 2.6 2.4 C5orf63 "FLJ44606, YDR286C" ENSG00000164241 "Chromosome 5 open reading frame 63" A6NC05 5 127042558-127073492 "Predicted intracellular proteins" "Electron transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in all" 43 "brain: 760.0;choroid plexus: 360.8" "Cell type enhanced" "Detected in many" "Spermatocytes: 49.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-87 MG: 49.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043240 Approved Approved Mitochondria NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Mitochondria "HPA043240: AB_10962511" "unprognostic (2.71e-1)" "unprognostic (3.97e-2)" "unprognostic (1.11e-1)" "unprognostic (2.63e-1)" "unprognostic (1.62e-1)" "unprognostic (1.93e-1)" "unprognostic (2.94e-4)" "unprognostic (1.34e-1)" "unprognostic (9.67e-2)" "unprognostic (3.40e-2)" "unprognostic (1.43e-4)" "unprognostic (1.07e-1)" "unprognostic (2.26e-2)" "unprognostic (1.21e-1)" "unprognostic (1.32e-1)" "unprognostic (3.64e-3)" "unprognostic (1.07e-2)" 3.3 3.7 412.4 4.3 388.9 4.0 6.5 381.5 760.0 2.6 360.8 7.7 6.4 5.3 4.2 5.5 4.6 4.2 6.9 415.7 402.6 6.0 5.3 4.1 8.2 430.5 432.1 3.7 5.3 6.7 6.9 3.3 445.4 5.5 11.9 13.1 4.6 4.1 5.0 4.0 7.0 3.6 371.7 4.2 7.7 12.8 391.3 5.9 8.8 6.4 8.3 4.8 2.8 416.6 0.9 4.0 1.1 2.3 2.9 4.6 0.6 4.2 0.5 5.2 3.0 9.8 12.2 0.0 17.1 3.4 7.5 1.5 7.3 4.6 7.4 1.6 6.2 10.1 15.6 11.9 7.2 6.0 0.5 4.6 11.6 6.6 3.4 3.6 4.5 4.2 0.7 1.8 5.1 8.1 0.2 5.5 0.7 8.4 3.0 4.4 2.5 7.0 5.8 6.0 9.8 8.0 5.5 2.5 0.3 2.1 10.1 8.8 3.5 10.8 10.0 12.5 2.7 6.0 16.5 0.4 49.8 0.8 5.7 5.8 0.4 5.0 7.5 1.7 6.2 15.4 6.9 8.3 3.7 14.2 10.1 7.7 1.6 15.7 0.4 12.2 12.5 3.4 412.4 388.9 381.5 760.0 415.7 402.6 430.5 432.1 445.4 371.7 391.3 416.6 2.9 6.4 11.7 18.9 11.3 1.0 11.3 19.9 8.6 11.9 6.9 4.2 33.7 4.3 8.6 16.5 14.6 10.1 12.5 14.6 19.6 16.8 30.2 7.5 1.0 4.6 10.8 9.9 4.3 10.2 9.2 4.3 12.2 5.6 10.1 7.1 3.9 10.0 5.4 0.0 6.7 11.7 10.2 1.0 1.9 17.5 2.5 1.6 8.8 15.9 1.8 11.7 19.6 11.1 1.2 12.4 17.2 2.2 6.1 6.2 10.5 5.8 13.2 10.6 6.6 4.6 2.7 49.8 19.3 11.9 1.1 2.7 6.6 8.2 13.7 11.7 C6orf118 "bA85G2.1, MGC23884" ENSG00000112539 "Chromosome 6 open reading frame 118" Q5T5N4 6 165279664-165309605 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.6;choroid plexus: 29.8;fallopian tube: 16.4" "Cell type enhanced" "Detected in some" "Early spermatids: 145.5;Endometrial ciliated cells: 140.4;Late spermatids: 57.6;Respiratory ciliated cells: 243.9" "Cancer enhanced" "Detected in some" "endometrial cancer: 2.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 2.7;SCLC-21H: 1.6" "Low region specificity" "Detected in many" "HPA029787, HPA029789" Approved Uncertain Mitochondria NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 12: NES - Nervous system development" "Cluster 49: Ciliated cells - Cilium organization" Mitochondria "HPA029787: AB_10599999, HPA029789: AB_10601002" "unprognostic (2.84e-1)" "unprognostic (3.09e-4)" "unprognostic (2.70e-2)" "unprognostic (7.99e-2)" "unprognostic (5.34e-2)" "unprognostic (1.41e-1)" "unprognostic (2.50e-1)" "unprognostic (4.27e-2)" "unprognostic (4.89e-2)" "unprognostic (8.18e-9)" "unprognostic (3.22e-3)" "unprognostic (3.03e-2)" "unprognostic (6.55e-3)" "unprognostic (4.50e-1)" 0.0 0.0 2.7 0.0 2.3 0.0 0.0 0.9 1.1 0.6 29.8 0.0 0.0 0.4 0.0 0.0 16.4 0.0 0.0 4.0 2.6 0.0 0.0 2.1 0.0 8.4 10.6 0.0 0.0 0.0 1.5 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 7.0 2.8 0.0 0.1 0.0 0.0 0.0 0.0 3.7 0.0 0.2 2.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 1.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 2.3 0.9 1.1 4.0 2.6 8.4 10.6 5.3 6.4 2.8 3.7 0.0 0.0 1.5 0.3 0.0 0.0 0.2 6.6 0.0 0.0 0.0 0.1 0.4 0.0 16.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 145.5 140.4 1.4 0.1 0.0 0.0 0.4 0.0 0.0 1.3 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 10.2 0.0 0.0 57.6 0.6 0.4 0.0 0.0 0.0 0.0 0.0 7.1 0.1 0.0 0.0 0.4 0.0 0.2 0.0 0.1 243.9 0.0 0.0 0.0 1.8 16.8 1.3 0.0 0.0 0.0 0.1 0.1 0.0 0.1 C9orf131 MGC41945 ENSG00000174038 "Chromosome 9 open reading frame 131" Q5VYM1 9 35041095-35045986 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 35.8" "Group enriched" "Detected in some" 18 "Early spermatids: 129.6;Late spermatids: 35.7" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 6.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "RT4: 9.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA022029 Approved Mitochondria NA NA "Cluster 46: Basophils - DNA binding" "Cluster 78: Testis - Spermatogenesis" "Cluster 15: RT4 - Unknown function" "Cluster 23: Spermatids - Flagellum & Golgi organization" Mitochondria "HPA022029: AB_10960628" "unprognostic (1.10e-2)" "unprognostic (8.99e-2)" "unprognostic (2.06e-1)" "unprognostic (1.31e-1)" "unprognostic (1.91e-1)" "unprognostic (1.23e-3)" "unprognostic (2.47e-1)" "unprognostic (6.57e-2)" "unprognostic (3.66e-1)" "unprognostic (9.45e-2)" "unprognostic (4.63e-2)" "unprognostic (1.75e-2)" "unprognostic (2.37e-2)" "unprognostic (9.34e-2)" "unprognostic (1.82e-1)" "unprognostic (9.90e-4)" "unprognostic (4.19e-3)" 0.3 0.2 0.8 0.5 0.8 2.6 0.7 6.3 2.2 1.3 0.3 0.6 0.3 2.7 1.3 0.2 0.1 2.1 0.4 1.3 1.0 0.4 0.7 0.2 0.8 0.8 0.1 0.2 0.2 0.4 0.1 0.5 0.8 0.2 0.7 1.4 0.1 0.1 1.3 1.1 0.3 0.2 0.0 0.5 0.4 35.8 1.1 0.1 0.7 0.0 0.2 0.5 0.0 1.8 2.0 0.3 0.2 0.1 0.4 0.0 0.8 0.4 0.0 0.0 0.0 0.6 1.2 0.4 0.2 0.0 0.7 1.4 0.0 0.0 0.2 0.3 0.3 0.8 2.0 0.5 0.0 0.3 0.7 0.0 0.3 0.0 0.0 0.0 0.3 0.7 1.8 1.6 0.0 0.4 0.3 0.8 0.4 0.5 0.0 0.0 0.2 0.0 0.2 9.1 0.2 0.0 0.5 0.0 0.3 0.3 0.5 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.4 0.8 0.0 0.1 0.8 0.5 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.8 0.8 6.3 2.2 1.3 1.0 0.8 0.1 0.8 0.0 1.1 1.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 129.6 0.5 0.5 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.0 0.0 35.7 1.5 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.3 0.0 4.4 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 CA5B ENSG00000169239 "Carbonic anhydrase 5B" Q9Y2D0 X 15688830-15788411 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 37.9;Muller glia cells: 35.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 22.3;fHDF/TERT166: 27.0;hTERT-HME1: 34.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA012618 Uncertain Supported Mitochondria NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" Mitochondria "HPA012618: AB_1846000" "unprognostic (1.62e-2)" "unprognostic (2.10e-3)" "unprognostic (2.86e-1)" "unprognostic (1.55e-3)" "unprognostic (1.16e-2)" "unprognostic (4.59e-5)" "unprognostic (2.50e-1)" "unprognostic (6.89e-4)" "unprognostic (4.11e-1)" "unprognostic (3.89e-3)" "unprognostic (1.54e-1)" "unprognostic (1.17e-1)" "prognostic favorable (6.66e-6)" "unprognostic (2.43e-1)" "unprognostic (1.38e-1)" "unprognostic (8.94e-2)" "unprognostic (3.08e-1)" 5.9 3.1 5.3 4.2 5.8 3.5 8.3 3.9 5.4 21.5 5.8 2.8 1.6 7.3 2.6 6.5 7.5 7.3 4.0 3.9 7.3 4.8 2.1 6.0 5.6 8.4 6.5 11.9 3.4 9.1 2.4 3.1 6.9 4.8 3.6 10.5 4.5 4.6 1.6 5.7 2.6 7.6 6.3 4.3 4.4 10.3 6.1 4.3 7.2 5.4 6.8 5.2 5.5 4.6 4.3 2.6 2.9 4.8 8.5 22.3 1.7 4.4 5.6 3.2 4.6 1.3 2.8 1.2 4.5 27.0 6.1 4.6 10.3 5.0 5.7 1.2 4.8 2.3 3.3 1.1 8.3 3.0 5.0 5.3 5.3 4.3 34.2 5.7 4.8 3.5 1.2 3.0 15.4 2.3 2.5 2.3 1.2 0.8 18.6 1.4 2.1 2.2 4.9 3.1 2.6 5.3 6.1 2.2 3.8 3.4 3.1 3.0 6.5 3.8 2.5 20.4 2.5 2.2 2.4 1.4 4.2 6.0 7.2 4.4 3.9 0.4 16.7 4.8 14.5 4.6 16.6 15.5 4.7 5.0 12.1 10.4 2.2 11.0 3.1 0.7 14.3 10.0 5.3 5.8 3.9 5.4 3.9 7.3 8.4 6.5 6.9 6.3 6.1 4.6 9.6 0.0 7.9 14.0 19.1 4.2 6.3 3.4 6.2 9.5 7.3 5.2 2.4 0.0 7.1 1.8 16.7 1.8 37.9 1.6 1.9 4.4 1.1 9.6 7.1 13.9 3.0 11.2 11.5 4.0 1.8 10.5 11.7 6.2 2.5 6.7 6.1 2.7 1.9 1.7 11.8 2.2 8.2 9.3 11.1 1.8 7.8 10.8 3.6 19.7 9.1 35.9 32.0 8.5 10.6 4.1 1.6 5.3 18.7 11.5 1.2 2.9 12.2 7.8 6.6 8.1 8.3 4.2 5.6 5.5 4.5 1.9 30.0 12.1 1.5 7.9 CACNA1B "CACNL1A5, CACNN, Cav2.2" ENSG00000148408 "Calcium voltage-gated channel subunit alpha1 B" Q00975 9 137877782-138124624 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.2;pituitary gland: 6.8;testis: 5.1" "Group enriched" "Detected in some" 8 "Excitatory neurons: 388.8;Inhibitory neurons: 330.9" "Cancer enhanced" "Detected in some" "testis cancer: 2.2" "Group enriched" "Detected in many" 8 "amygdala: 5.9;basal ganglia: 7.8;cerebral cortex: 10.2;hippocampal formation: 3.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SCLC-21H: 19.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022919, HPA044347" Uncertain Approved Mitochondria NA NA "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Mitochondria "HPA022919: , HPA044347: AB_10960837" "unprognostic (1.34e-3)" "unprognostic (2.70e-2)" "unprognostic (8.08e-2)" "unprognostic (2.51e-7)" "unprognostic (8.10e-2)" "unprognostic (1.51e-2)" "unprognostic (1.33e-1)" "unprognostic (3.10e-1)" "unprognostic (2.50e-1)" "unprognostic (2.36e-2)" "unprognostic (9.73e-4)" "unprognostic (5.98e-2)" "unprognostic (6.63e-6)" "unprognostic (4.25e-2)" "unprognostic (4.72e-1)" "unprognostic (7.77e-3)" "unprognostic (8.69e-2)" 0.0 2.8 5.9 0.1 7.8 0.0 0.0 0.8 10.2 0.3 0.0 0.4 0.0 0.0 0.6 0.0 3.1 0.4 0.3 3.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.8 6.8 0.0 0.0 0.5 0.1 3.5 0.0 0.4 0.0 0.2 0.2 0.1 0.0 0.0 0.3 5.1 0.0 1.2 0.2 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.5 3.7 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 7.8 0.8 10.2 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 43.4 0.0 0.0 0.1 0.0 0.0 11.7 0.2 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 3.4 0.0 0.2 0.1 0.0 0.0 388.8 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 6.7 330.9 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 17.8 0.6 1.7 0.0 16.1 10.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.2 8.2 9.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 CARD19 "bA370F5.1, BinCARD, C9orf89, MGC11115" ENSG00000165233 "Caspase recruitment domain family member 19" Q96LW7 9 93096217-93113283 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Macrophages: 142.0;Pancreatic endocrine cells: 121.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 134.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010921, HPA010990, HPA038297" Approved Supported Mitochondria NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 51: Myeloid cells - Hemostasis" Mitochondria "HPA010921: AB_10670295, HPA010990: AB_2668400, HPA038297: AB_2675938" "unprognostic (7.26e-2)" "unprognostic (1.15e-2)" "unprognostic (2.97e-1)" "unprognostic (2.66e-2)" "prognostic unfavorable (7.47e-5)" "unprognostic (2.22e-1)" "prognostic unfavorable (1.32e-5)" "unprognostic (1.21e-1)" "unprognostic (1.36e-2)" "unprognostic (2.65e-2)" "unprognostic (1.98e-1)" "unprognostic (9.13e-2)" "unprognostic (6.82e-2)" "unprognostic (2.29e-1)" "unprognostic (5.48e-2)" "unprognostic (1.03e-1)" "unprognostic (1.41e-1)" 12.2 13.7 2.5 3.7 2.1 3.2 11.3 4.8 4.5 11.5 3.1 14.4 6.1 12.0 2.6 11.0 10.8 5.8 10.3 1.8 3.4 16.2 10.8 10.9 4.0 4.0 2.9 7.9 5.5 6.1 6.6 3.3 4.9 8.7 3.2 0.1 9.4 4.2 14.2 10.8 9.5 4.2 3.6 10.5 12.9 19.1 3.5 3.1 8.7 5.5 2.6 11.5 11.5 5.9 33.0 31.3 4.1 9.2 5.3 10.1 12.9 26.7 13.0 18.2 8.2 7.8 10.6 7.0 18.3 9.5 15.4 56.0 3.3 21.9 1.5 134.9 12.3 12.4 6.5 18.4 21.1 11.2 11.4 23.5 8.1 13.2 5.2 20.0 21.4 6.1 5.7 13.8 12.4 64.7 12.1 30.0 3.6 21.1 70.8 8.2 20.7 29.4 22.9 12.1 9.8 17.3 14.4 6.9 30.6 0.8 15.6 11.6 21.6 9.3 18.6 17.9 8.4 10.4 10.1 1.5 39.0 11.3 32.4 27.8 37.4 23.6 10.2 30.0 10.5 12.6 10.0 10.9 30.6 7.5 9.0 8.9 40.3 18.4 17.3 11.1 21.7 22.4 2.5 2.1 4.8 4.5 1.8 3.4 4.0 2.9 4.9 3.6 3.5 5.9 29.3 22.4 20.9 0.0 14.4 0.0 52.8 0.0 25.6 12.0 81.2 75.6 0.0 27.1 5.6 16.5 16.7 22.9 25.7 27.7 62.6 76.6 49.5 19.4 26.8 34.1 15.8 7.8 0.0 58.1 34.6 26.2 36.2 20.3 30.3 8.2 41.7 13.9 79.0 5.0 0.0 19.8 0.0 41.3 0.0 15.3 45.7 142.0 0.0 0.0 68.3 21.9 17.5 0.0 0.0 121.6 10.3 43.6 15.0 58.7 38.9 61.7 2.2 29.8 59.2 30.4 31.1 98.7 26.4 27.9 0.0 21.6 34.0 8.5 18.6 71.0 CASP9 "APAF-3, ICE-LAP6, MCH6, PPP1R56" ENSG00000132906 "Caspase 9" P55211 1 15490832-15526534 "Cancer-related genes, Enzymes, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 35.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001473, CAB004348, HPA046488" Approved Approved Mitochondria NA NA "Cluster 46: Basophils - DNA binding" "Cluster 35: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 41: Macrophages - Immune response" Mitochondria "CAB004348: AB_673489, HPA001473: AB_1078401, HPA046488: AB_2679670" "prognostic favorable (5.91e-4)" "unprognostic (2.42e-1)" "unprognostic (8.94e-3)" "unprognostic (7.84e-2)" "unprognostic (1.93e-2)" "unprognostic (8.54e-3)" "unprognostic (1.90e-3)" "unprognostic (6.75e-2)" "unprognostic (2.58e-1)" "unprognostic (1.29e-1)" "unprognostic (9.09e-2)" "unprognostic (1.98e-1)" "unprognostic (1.39e-2)" "unprognostic (2.35e-1)" "unprognostic (3.21e-2)" "unprognostic (5.48e-2)" "prognostic favorable (1.67e-5)" 12.0 50.8 14.1 7.0 14.5 11.5 8.9 16.1 18.8 19.3 13.3 11.8 6.4 14.4 12.5 14.1 22.5 9.4 16.4 14.2 13.0 20.7 14.8 10.8 6.9 14.8 14.2 57.6 37.8 12.0 32.4 7.1 14.1 19.2 5.3 12.3 8.9 9.8 12.7 5.5 11.0 6.6 13.6 10.6 12.4 25.9 14.6 8.7 25.9 9.4 7.9 12.9 12.8 17.1 10.4 17.8 4.6 8.9 11.0 5.4 5.3 7.5 9.9 11.1 12.7 12.5 10.1 13.4 16.2 7.5 13.1 4.2 10.5 8.2 11.7 5.9 11.6 9.8 32.8 10.8 10.8 10.6 11.5 9.7 11.5 15.3 3.8 8.3 8.7 13.3 20.4 13.4 5.8 5.2 3.3 8.6 5.9 11.3 8.2 7.4 13.4 16.4 12.3 6.7 4.4 9.0 9.6 1.8 15.6 12.1 5.7 7.9 4.8 13.8 5.8 15.6 5.1 13.3 21.5 16.3 8.9 9.9 5.0 54.2 24.7 54.8 11.0 17.4 8.2 21.3 6.6 7.6 25.1 30.0 3.1 4.8 36.3 29.3 18.9 11.4 6.9 15.0 14.1 14.5 16.1 18.8 14.2 13.0 14.8 14.2 14.1 13.6 14.6 17.1 2.8 3.2 3.7 18.3 17.1 2.9 8.2 5.0 4.6 3.2 7.0 4.7 9.3 11.5 7.3 18.4 6.2 17.0 8.0 7.0 1.9 7.5 12.6 10.9 5.2 3.3 3.0 5.7 7.9 9.1 10.8 5.6 12.8 7.6 1.3 5.7 4.2 4.7 9.5 5.0 9.9 6.3 6.1 4.8 12.9 5.5 2.1 12.9 0.0 6.5 4.8 7.5 10.3 9.5 8.8 8.4 7.3 3.8 9.9 4.0 9.8 7.2 8.9 6.3 0.0 5.3 9.7 16.4 7.1 6.0 2.4 35.7 6.4 7.9 5.6 7.4 CCDC120 JM11 ENSG00000147144 "Coiled-coil domain containing 120" Q96HB5 X 49053572-49069857 "Cancer-related genes, Predicted intracellular proteins" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 35.9;skin 1: 29.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A-431: 20.9;BEWO: 28.6;HaCaT: 19.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000561 Uncertain Mitochondria NA NA "Cluster 17: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 44: Endometrium - Transcription" Mitochondria "HPA000561: AB_2244190" "unprognostic (1.65e-1)" "unprognostic (1.79e-1)" "unprognostic (1.19e-1)" "unprognostic (7.59e-3)" "unprognostic (1.80e-3)" "unprognostic (1.08e-2)" "unprognostic (2.59e-3)" "unprognostic (1.23e-1)" "unprognostic (1.04e-1)" "unprognostic (1.72e-1)" "unprognostic (1.43e-1)" "unprognostic (1.66e-2)" "unprognostic (4.85e-2)" "unprognostic (2.64e-2)" "unprognostic (3.82e-3)" "unprognostic (4.54e-3)" "unprognostic (2.34e-3)" 3.1 2.6 5.2 2.1 5.0 2.3 4.4 7.6 6.4 10.6 4.5 5.2 8.7 4.4 5.7 35.9 5.0 2.5 1.8 5.0 4.8 9.1 6.6 4.3 2.0 3.9 4.0 6.3 8.0 3.8 9.3 4.0 3.9 7.7 2.2 2.0 12.0 4.0 0.7 29.3 7.4 1.6 3.0 3.8 6.8 3.4 4.9 2.9 6.0 0.5 3.9 5.3 16.1 3.5 20.9 2.8 4.5 0.2 0.0 0.0 28.6 0.7 1.0 1.5 2.4 6.9 8.7 0.8 3.2 1.2 3.4 19.5 3.4 11.7 0.1 5.4 6.6 2.0 5.0 2.4 1.5 0.1 3.4 2.5 9.0 1.9 0.5 3.1 2.5 5.4 2.9 0.2 0.0 17.5 7.5 0.5 5.1 9.8 0.1 6.6 3.3 2.0 8.8 11.0 6.0 4.7 3.6 7.2 2.2 6.1 17.7 2.8 1.2 0.1 5.2 0.2 0.2 6.6 4.8 0.1 0.2 0.1 0.9 1.1 0.2 0.5 0.3 0.0 0.2 0.2 0.4 0.3 0.0 0.6 0.4 0.3 1.0 0.4 0.1 0.6 0.1 0.1 5.2 5.0 7.6 6.4 5.0 4.8 3.9 4.0 3.9 3.0 4.9 3.5 1.7 6.4 3.1 2.0 2.5 5.1 3.5 7.1 4.0 6.8 8.2 5.6 1.3 4.3 6.0 12.9 4.2 12.7 2.2 5.6 0.0 5.1 0.1 8.5 2.2 2.7 6.0 1.7 4.8 6.5 3.2 2.9 9.7 11.5 0.0 4.9 2.5 2.5 2.3 10.1 6.2 6.2 2.0 1.2 1.5 0.5 2.1 0.9 0.0 2.8 0.4 3.3 2.1 2.5 0.7 14.4 8.3 1.2 1.5 6.3 9.0 3.1 5.0 6.8 0.0 2.6 1.5 1.4 2.4 9.0 9.2 16.8 2.3 2.3 4.6 11.4 CCDC191 KIAA1407 ENSG00000163617 "Coiled-coil domain containing 191" Q8NCU4 3 113964137-114056594 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 37.5;Endometrial ciliated cells: 68.0;Respiratory ciliated cells: 104.2;Rod photoreceptor cells: 40.4;Spermatocytes: 68.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047833 Approved Approved Mitochondria NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" Mitochondria "HPA047833: AB_10961639" "unprognostic (2.59e-2)" "unprognostic (3.93e-2)" "unprognostic (1.86e-1)" "unprognostic (1.31e-2)" "unprognostic (2.60e-1)" "unprognostic (1.42e-2)" "unprognostic (6.57e-2)" "unprognostic (5.91e-2)" "unprognostic (1.08e-1)" "unprognostic (2.90e-1)" "unprognostic (6.33e-2)" "unprognostic (3.64e-2)" "unprognostic (2.53e-2)" "unprognostic (1.51e-1)" "unprognostic (3.62e-1)" "unprognostic (1.54e-1)" "prognostic favorable (3.45e-4)" 2.9 3.3 4.2 3.1 3.9 2.9 4.7 3.1 4.4 4.6 11.7 3.4 1.8 5.3 7.9 2.5 12.1 3.5 1.8 3.8 4.0 7.7 1.9 4.7 4.4 5.7 5.7 4.8 5.1 7.9 10.9 2.1 4.2 5.0 3.2 14.0 3.6 4.8 0.9 7.6 4.0 2.7 4.7 5.6 3.1 9.7 4.0 2.8 8.3 0.8 4.1 3.5 3.3 4.0 3.7 1.9 3.0 2.5 0.8 4.3 0.9 0.8 1.5 1.1 1.8 0.4 4.1 1.0 1.4 1.5 1.0 4.6 0.9 1.6 2.6 0.7 0.7 0.8 0.7 0.3 1.2 1.1 0.5 1.8 4.2 1.5 2.2 2.0 2.2 2.8 0.3 2.1 0.7 1.6 2.3 0.4 0.5 2.4 1.4 1.4 0.6 2.0 4.2 1.8 1.8 2.9 1.5 0.3 1.5 1.5 7.2 0.4 2.4 2.1 0.5 0.9 0.5 3.0 2.6 3.5 2.7 0.6 1.0 0.1 0.8 1.6 0.9 0.8 1.0 8.9 1.8 1.5 0.9 8.3 0.9 1.5 4.4 0.8 0.5 3.7 1.4 0.9 4.2 3.9 3.1 4.4 3.8 4.0 5.7 5.7 4.2 4.7 4.0 4.0 5.2 12.8 14.4 0.0 20.0 0.0 4.0 0.0 4.6 8.9 5.7 7.0 0.0 0.0 16.1 12.9 37.5 1.8 7.9 1.5 13.7 5.4 27.1 68.0 9.5 3.7 4.9 2.1 0.0 3.6 0.5 4.0 9.7 10.6 1.3 9.1 4.6 1.3 3.0 20.2 0.0 2.3 0.0 3.2 0.0 13.1 4.1 3.0 0.0 0.0 2.0 21.6 4.1 0.0 0.0 2.6 1.0 5.3 3.0 1.7 2.4 5.0 104.2 40.4 0.0 6.3 3.5 68.3 13.3 4.3 0.0 0.3 4.5 8.1 2.7 2.8 CCDC90B "MDS011, MDS025" ENSG00000137500 "Coiled-coil domain containing 90B" Q9GZT6 11 83259097-83286407 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 447.3;Late spermatids: 233.9;Spermatocytes: 333.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011130, HPA011931" Supported Enhanced Mitochondria NA NA "Cluster 10: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 34: Spermatids - Unknown function" Mitochondria "HPA011130: AB_1846170, HPA011931: AB_2072332" "unprognostic (5.85e-2)" "unprognostic (1.33e-1)" "unprognostic (7.34e-2)" "unprognostic (9.71e-2)" "unprognostic (1.34e-1)" "unprognostic (7.48e-2)" "unprognostic (2.99e-1)" "unprognostic (3.57e-3)" "unprognostic (5.76e-3)" "unprognostic (3.53e-2)" "unprognostic (6.01e-3)" "unprognostic (2.01e-2)" "unprognostic (1.00e-2)" "unprognostic (2.31e-1)" "unprognostic (3.03e-1)" "unprognostic (1.62e-1)" "unprognostic (2.41e-1)" 16.4 37.3 23.2 13.0 24.5 16.1 21.3 24.2 29.8 17.1 23.3 18.1 14.7 14.7 33.8 16.2 15.6 18.2 22.1 22.9 25.4 18.4 38.9 13.5 20.5 25.3 25.0 22.3 18.3 14.9 19.4 22.2 25.0 16.0 17.3 12.6 17.1 16.3 16.2 14.1 16.6 16.7 25.2 15.5 16.9 54.5 24.4 17.2 25.6 17.7 17.0 15.3 14.2 27.1 19.1 27.3 46.1 15.2 59.6 44.7 27.7 37.4 31.6 22.7 24.3 32.2 63.0 46.7 47.7 55.0 47.5 23.5 20.1 47.3 30.3 31.9 16.0 28.2 17.7 27.3 50.1 29.2 23.5 50.2 62.3 29.5 83.8 45.3 52.3 49.6 41.9 37.9 83.7 33.5 29.4 36.7 37.9 80.2 33.4 33.1 40.9 39.3 47.3 27.5 22.2 50.9 26.4 21.0 26.1 60.8 53.9 26.4 51.6 44.8 28.8 85.9 26.0 36.3 51.2 46.8 18.1 23.2 45.5 77.7 18.7 71.6 24.2 41.3 31.2 39.8 34.7 34.2 27.0 37.9 30.2 30.2 9.8 50.7 43.8 20.4 46.0 27.4 23.2 24.5 24.2 29.8 22.9 25.4 25.3 25.0 25.0 25.2 24.4 27.1 50.8 12.8 13.1 14.0 40.5 23.6 49.6 102.8 26.7 36.3 33.5 49.7 58.0 28.6 48.3 36.8 14.6 74.0 41.4 21.0 68.4 59.4 447.3 39.5 38.0 45.8 33.6 36.2 16.0 48.5 55.4 44.5 26.5 31.4 49.4 83.0 35.7 43.3 63.7 42.1 23.3 35.2 52.9 34.6 32.4 233.9 42.6 38.6 21.4 10.3 52.8 35.3 53.5 31.2 48.2 67.6 32.9 25.6 44.6 38.9 44.1 78.0 32.6 50.0 26.3 40.3 43.5 333.0 107.8 32.5 29.0 51.7 37.1 86.8 31.2 49.9 CCM2 "C7orf22, MGC4607, OSM" ENSG00000136280 "CCM2 scaffold protein" Q9BSQ5 7 44999475-45076469 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 140.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020273, HPA021669, HPA065815" Supported Enhanced Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 3: Monocytes - Immune response regulation" Mitochondria "HPA020273: AB_1846185, HPA021669: AB_1846186, HPA065815: AB_2685562" "unprognostic (4.30e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (1.79e-4)" "unprognostic (3.17e-1)" "prognostic unfavorable (2.45e-4)" "unprognostic (4.85e-2)" "unprognostic (1.55e-2)" "unprognostic (7.37e-3)" "unprognostic (3.92e-1)" "unprognostic (2.65e-1)" "prognostic favorable (1.16e-4)" "unprognostic (3.03e-1)" "prognostic unfavorable (5.06e-7)" "unprognostic (2.45e-1)" "unprognostic (1.79e-1)" "unprognostic (2.81e-2)" "unprognostic (2.48e-1)" 32.7 40.7 62.5 25.1 74.5 15.5 26.6 58.7 89.1 19.1 48.4 30.2 13.2 20.3 6.4 22.4 18.9 11.5 37.1 63.0 62.4 24.2 86.0 29.2 43.6 67.6 62.8 16.1 26.6 21.4 30.4 14.5 69.2 23.8 10.8 9.4 18.8 14.5 48.2 21.1 27.6 16.9 60.0 54.6 24.0 30.3 71.5 45.4 18.7 36.9 29.6 27.2 20.0 68.6 38.7 41.8 24.4 49.2 45.5 39.8 17.7 45.9 37.3 32.0 43.3 30.6 39.3 53.7 34.5 58.5 101.8 49.5 15.3 58.9 21.4 61.0 29.7 23.3 34.0 22.1 39.9 9.9 61.5 44.7 38.0 56.3 24.0 30.0 59.2 76.8 27.5 42.1 64.7 58.2 47.9 131.6 28.4 32.3 46.1 25.7 14.2 43.9 33.1 36.8 46.9 36.8 37.5 29.2 20.9 31.7 33.3 45.7 45.1 43.4 36.4 44.2 44.8 75.9 64.0 109.2 42.3 35.7 53.4 108.1 33.5 105.8 52.2 40.2 35.2 42.0 62.3 57.4 23.6 43.6 58.9 44.1 103.9 60.9 47.7 23.8 167.1 40.2 62.5 74.5 58.7 89.1 63.0 62.4 67.6 62.8 69.2 60.0 71.5 68.6 28.7 19.2 19.4 26.1 57.5 46.8 22.6 27.6 54.7 19.0 13.5 24.6 13.0 20.0 18.8 14.7 4.2 28.3 53.7 30.5 25.4 30.2 6.9 6.0 14.3 26.7 15.6 13.7 33.3 38.5 35.8 25.0 11.2 7.4 36.1 23.8 30.4 56.5 49.3 82.4 24.9 15.2 12.2 47.9 51.1 12.8 21.1 47.7 33.8 56.2 140.0 34.1 122.6 20.1 51.7 45.3 11.4 20.3 69.1 40.4 13.6 22.9 8.0 14.4 19.7 16.2 29.6 15.3 37.8 16.8 23.0 10.4 55.7 36.9 15.2 19.7 CCN6 "WISP-3, WISP3" ENSG00000112761 "Cellular communication network factor 6" O95389 6 112054075-112069686 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "epididymis: 10.2" "Cell type enriched" "Detected in single" 7 "Cardiomyocytes: 2.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 49 "RT4: 12.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA064196 Supported Mitochondria "Secreted to extracellular matrix" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 15: RT4 - Unknown function" "Cluster 43: Cardiomyocytes - Nuclear processes" Mitochondria "HPA064196: AB_2685209" "unprognostic (2.13e-2)" "unprognostic (7.90e-3)" "unprognostic (5.00e-2)" "unprognostic (2.22e-2)" "unprognostic (3.76e-1)" "unprognostic (6.52e-2)" "unprognostic (1.98e-3)" "unprognostic (4.07e-3)" "unprognostic (1.82e-1)" "unprognostic (3.90e-1)" "unprognostic (1.02e-2)" "unprognostic (4.81e-2)" "unprognostic (1.80e-2)" "unprognostic (1.50e-2)" "unprognostic (3.11e-1)" "unprognostic (4.91e-2)" "unprognostic (2.93e-2)" 0.0 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.0 0.3 0.0 0.0 0.1 0.0 10.2 0.0 2.3 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.2 0.2 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 12.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 CCR7 "BLR2, CD197, CDw197, CMKBR7, EBI1" ENSG00000126353 "C-C motif chemokine receptor 7" P32248 17 40553769-40565472 "Cancer-related genes, CD markers, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 21.3;lymphoid tissue: 84.0" "Group enriched" "Detected in many" 4 "Langerhans cells: 415.0;monocytes: 1586.1;Syncytiotrophoblasts: 517.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in all" "naive CD4 T-cell: 4597.2" "Lineage enriched" "Detected in all" 4 "T-cells: 4597.2" "Cell line enriched" "Detected in some" 82 "HDLM-2: 1386.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB003796, HPA031383, HPA074467" Enhanced Enhanced Mitochondria NA NA "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" Mitochondria "CAB003796: AB_562261, HPA031383: AB_2673854, HPA074467: AB_2686693" "prognostic favorable (3.84e-4)" "prognostic favorable (8.03e-6)" "unprognostic (2.26e-3)" "unprognostic (1.32e-3)" "unprognostic (2.35e-3)" "prognostic favorable (7.61e-7)" "unprognostic (2.71e-4)" "unprognostic (2.58e-2)" "unprognostic (4.48e-2)" "unprognostic (4.68e-4)" "unprognostic (1.10e-2)" "unprognostic (3.11e-1)" "unprognostic (1.08e-3)" "unprognostic (3.12e-1)" "prognostic unfavorable (7.72e-4)" "unprognostic (1.02e-1)" "unprognostic (7.95e-2)" 4.6 0.6 0.0 67.2 0.3 15.2 2.3 0.0 0.2 2.7 0.6 3.6 1.2 1.6 0.0 2.0 3.9 5.1 2.5 0.1 0.0 2.1 2.3 2.7 84.0 0.2 0.1 1.8 0.6 0.1 1.4 1.1 0.2 1.9 5.1 0.5 1.8 0.3 0.5 2.2 21.3 0.9 0.0 28.6 5.3 1.9 0.2 58.8 2.8 0.4 83.3 8.8 2.0 0.8 0.4 1.5 0.0 0.0 0.0 0.3 16.8 0.4 0.1 0.0 0.0 0.2 0.0 0.6 0.9 0.0 0.1 0.2 0.0 0.0 0.0 1386.6 0.1 0.0 0.2 0.5 0.0 3.9 0.0 0.5 0.0 0.0 0.0 1.9 0.0 0.3 0.8 0.2 0.0 0.4 1.2 3.0 0.1 0.0 0.0 4.5 0.9 0.0 0.0 0.6 0.0 0.0 0.0 0.6 0.2 1.0 0.6 1.6 0.0 0.4 0.1 1.6 0.7 7.5 0.9 9.0 1.9 0.1 0.0 25.6 6.5 4.2 61.1 3.5 69.2 794.6 996.2 285.4 4.2 1122.5 4597.2 2462.0 45.3 970.9 6.4 58.5 637.3 2489.9 0.0 0.3 0.0 0.2 0.1 0.0 0.2 0.1 0.2 0.0 0.2 0.8 1.2 0.0 3.7 0.0 201.4 5.0 1.5 0.0 0.0 0.0 0.7 0.4 0.3 0.0 1.3 1.8 0.0 143.8 9.5 0.0 0.0 0.6 0.3 0.5 0.3 1.0 0.0 0.4 0.0 8.3 24.2 1.6 1.1 0.4 2.5 0.0 0.4 0.0 12.8 0.0 0.0 0.0 0.0 0.0 415.0 0.2 0.0 75.7 16.0 0.0 1586.1 0.4 3.1 0.0 0.1 0.5 0.0 0.0 3.6 0.2 0.0 0.3 0.0 0.0 0.0 0.2 2.4 0.6 0.8 0.0 4.4 517.6 75.2 0.1 0.0 4.6 CD101 "IGSF2, V7" ENSG00000134256 "CD101 molecule" Q93033 1 117001750-117036476 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.6;intestine: 6.1;lung: 6.5" "Cell type enhanced" "Detected in some" "Kupffer cells: 6.7;Macrophages: 9.0;monocytes: 6.0;Oligodendrocyte precursor cells: 4.5;Sertoli cells: 6.6;Skeletal myocytes: 4.8;T-cells: 5.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "eosinophil: 92.7" "Group enriched" "Detected in many" 18 "dendritic cells: 32.6;granulocytes: 92.7;monocytes: 51.5" "Cell line enriched" "Detected in some" 8 "HMC-1: 27.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA049527, HPA057763" Approved Uncertain Mitochondria NA NA 630000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Mitochondria "HPA049527: , HPA057763: AB_2683519" "unprognostic (1.25e-1)" "unprognostic (7.95e-3)" "unprognostic (5.40e-3)" "unprognostic (4.10e-3)" "unprognostic (2.62e-1)" "unprognostic (4.00e-2)" "unprognostic (3.03e-2)" "unprognostic (3.58e-3)" "unprognostic (3.57e-2)" "unprognostic (7.29e-3)" "unprognostic (3.15e-1)" "unprognostic (4.54e-2)" "unprognostic (7.15e-6)" "unprognostic (7.00e-2)" "unprognostic (8.07e-2)" "unprognostic (5.05e-2)" "unprognostic (5.28e-2)" 0.4 0.7 0.2 3.2 0.2 4.6 0.6 0.0 0.3 0.4 0.1 1.8 3.4 0.6 0.4 0.9 0.5 1.1 0.4 0.2 0.0 0.2 0.6 6.5 1.9 0.2 0.1 0.3 0.9 0.0 0.1 0.2 0.1 0.6 2.3 0.1 1.4 0.4 0.1 0.9 6.1 1.3 0.2 3.0 1.4 0.4 0.1 1.2 0.3 0.0 1.4 1.2 0.6 0.2 0.5 0.0 0.9 3.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.1 1.4 2.1 0.1 0.0 0.0 1.2 0.1 1.0 0.0 0.0 0.2 27.3 0.3 1.4 0.0 0.1 0.2 0.2 0.5 0.1 0.7 0.1 1.8 0.0 3.3 0.9 0.0 0.0 0.0 0.5 0.0 0.7 0.7 0.4 0.7 0.5 0.6 0.3 0.6 1.0 0.7 0.5 0.1 0.4 0.5 0.2 0.2 0.1 0.0 0.8 2.1 1.7 0.1 20.3 92.7 0.3 26.3 1.8 0.3 0.6 3.2 32.6 0.0 0.9 3.0 0.8 0.0 51.5 0.1 3.0 7.4 0.2 0.2 0.0 0.3 0.2 0.0 0.2 0.1 0.1 0.2 0.1 0.2 0.1 0.0 1.1 2.0 0.6 1.3 0.2 0.1 0.6 0.0 1.0 0.6 0.9 0.0 0.1 0.0 0.0 0.0 0.5 0.2 0.0 0.3 2.1 0.1 0.3 0.1 1.8 0.0 1.8 0.6 0.0 0.7 1.1 0.9 1.3 0.8 0.0 0.5 0.6 0.0 1.1 0.0 2.0 6.7 3.9 2.4 0.3 9.0 0.0 1.0 6.0 0.0 0.0 4.5 0.3 0.2 0.1 1.2 0.5 0.3 0.1 0.0 0.8 0.0 6.6 4.8 0.5 0.0 0.1 0.4 1.6 0.0 5.1 1.1 0.2 0.1 CDRT4 FLJ36674 ENSG00000239704 "CMT1A duplicated region transcript 4" Q8N9R6 17 15436015-15503608 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 36 "Early spermatids: 65.8;Late spermatids: 202.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 10.1;NB-4: 8.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA021590 Uncertain Approved Mitochondria NA NA "Cluster 46: Basophils - DNA binding" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "HPA021590: AB_1848906" "unprognostic (5.46e-6)" "unprognostic (9.47e-2)" "unprognostic (7.53e-2)" "unprognostic (1.31e-1)" "unprognostic (3.51e-2)" "unprognostic (7.74e-3)" "unprognostic (9.29e-2)" "unprognostic (2.12e-2)" "unprognostic (3.93e-2)" "unprognostic (1.39e-1)" "unprognostic (2.10e-5)" "unprognostic (2.00e-3)" "unprognostic (1.74e-6)" "unprognostic (1.00e-1)" "unprognostic (4.17e-1)" "unprognostic (4.18e-1)" "unprognostic (9.27e-2)" 5.8 18.7 14.1 1.7 12.9 6.1 9.3 14.3 12.0 19.3 13.2 10.6 0.9 8.8 23.7 10.8 20.7 3.2 5.7 12.2 13.9 16.5 10.0 8.8 5.0 11.7 13.5 20.4 19.8 1.5 48.0 2.5 11.6 20.1 4.6 11.8 15.9 3.8 1.8 21.8 11.9 2.3 8.4 15.9 11.4 15.3 14.7 3.2 23.5 0.8 2.9 9.0 12.8 12.0 2.5 2.2 2.8 1.0 2.4 1.7 2.9 0.9 2.5 1.1 1.0 1.4 0.7 0.0 1.2 1.4 0.2 0.8 3.0 2.4 1.7 0.5 0.4 0.4 2.0 10.1 0.7 0.9 3.9 1.9 3.6 1.6 4.0 4.3 2.6 1.0 0.5 1.6 2.1 0.4 1.0 8.0 0.9 0.4 0.8 0.4 0.0 0.0 2.9 2.0 0.4 1.3 0.8 0.4 0.8 6.2 1.1 2.0 2.4 0.3 1.1 1.0 1.0 2.2 0.9 0.1 0.0 0.0 0.3 0.9 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.1 14.1 12.9 14.3 12.0 12.2 13.9 11.7 13.5 11.6 8.4 14.7 12.0 0.4 0.0 1.1 0.0 0.3 0.1 0.2 0.2 0.0 1.4 0.6 0.5 0.1 0.0 0.1 0.0 0.0 0.4 0.2 0.6 0.0 0.8 65.8 0.7 0.2 0.2 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.4 2.5 1.4 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 202.7 0.0 0.1 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.6 1.8 0.0 0.0 0.4 0.4 0.0 3.7 1.5 0.0 0.3 0.2 1.0 0.7 0.0 0.0 0.1 0.2 0.5 1.0 0.3 CEND1 "BM88, FLJ90066" ENSG00000184524 "Cell cycle exit and neuronal differentiation 1" Q8N111 11 787115-790113 "Predicted membrane proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 234.7" "Cell type enhanced" "Detected in some" "Bipolar cells: 94.2;Excitatory neurons: 42.9;Horizontal cells: 75.7;Inhibitory neurons: 45.6;Rod photoreceptor cells: 25.5" "Cancer enriched" "Detected in many" 13 "glioma: 24.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 13.6;Karpas-707: 31.0;SCLC-21H: 54.1;SH-SY5Y: 20.4;U-266/70: 21.1;U-87 MG: 28.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042527 Enhanced Supported Approved Mitochondria NA NA "Cluster 35: T-regs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" Mitochondria "HPA042527: AB_2678038" "unprognostic (4.62e-3)" "unprognostic (1.34e-4)" "unprognostic (9.66e-3)" "unprognostic (1.27e-2)" "prognostic unfavorable (4.38e-5)" "unprognostic (2.20e-3)" "unprognostic (4.11e-2)" "unprognostic (6.72e-2)" "unprognostic (2.60e-2)" "unprognostic (2.26e-1)" "unprognostic (2.00e-3)" "unprognostic (4.24e-3)" "unprognostic (1.94e-3)" "unprognostic (4.43e-2)" "unprognostic (1.71e-1)" "unprognostic (1.40e-1)" "unprognostic (1.03e-1)" 0.1 5.5 55.0 1.0 78.8 0.0 0.1 56.9 234.7 0.2 20.0 4.0 0.6 0.9 0.2 0.4 0.1 0.0 1.1 67.4 79.3 1.2 0.3 0.2 0.3 103.8 57.9 0.2 0.2 0.3 26.0 0.0 93.4 3.2 0.1 7.6 0.2 1.5 0.2 0.2 1.4 0.5 21.6 0.3 0.9 0.3 106.3 0.0 0.2 0.0 0.1 0.8 1.1 116.6 0.0 0.7 0.7 1.4 0.2 0.3 0.2 1.3 0.4 0.4 0.6 0.0 0.0 0.0 0.0 0.5 13.6 0.5 0.0 0.0 0.0 8.5 0.3 0.0 0.1 0.0 0.1 0.0 5.3 0.6 0.0 0.8 0.0 0.0 0.2 0.0 0.0 31.0 0.5 0.1 0.3 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.0 0.0 54.1 20.4 0.0 0.4 0.0 0.0 0.0 0.1 0.2 0.1 0.0 1.2 0.9 21.1 6.2 1.3 28.6 0.2 0.4 0.0 0.0 0.0 0.2 0.2 0.0 0.8 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 55.0 78.8 56.9 234.7 67.4 79.3 103.8 57.9 93.4 21.6 106.3 116.6 0.1 0.0 0.0 17.6 0.5 0.1 0.1 0.0 0.0 94.2 0.0 0.0 0.5 0.0 0.0 0.0 10.4 0.0 0.3 0.0 0.0 0.1 0.2 0.0 0.4 0.6 0.0 0.0 42.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.1 75.7 45.6 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 6.5 0.0 6.7 0.0 15.1 10.0 0.0 0.0 0.0 1.0 0.1 0.0 0.1 0.0 25.5 0.0 0.1 1.7 0.0 0.7 0.0 0.0 0.0 0.3 0.2 0.1 0.0 CHAC1 MGC4504 ENSG00000128965 "ChaC glutathione specific gamma-glutamylcyclotransferase 1" Q9BUX1 15 40952962-40956512 "Enzymes, Predicted intracellular proteins" "Apoptosis, Neurogenesis, Notch signaling pathway, Unfolded protein response" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 68.6;skeletal muscle: 68.4" "Cell type enhanced" "Detected in many" "Distal tubular cells: 35.2;Exocrine glandular cells: 27.8;Gastric mucus-secreting cells: 33.6;Pancreatic endocrine cells: 19.3;Plasma cells: 21.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 109.5;HHSteC: 80.7;hTCEpi: 130.8;SK-MEL-30: 95.0;U-266/70: 81.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA042708, HPA043505" Approved Approved Mitochondria NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 1: Pancreatic cells - Digestion" Mitochondria "HPA042708: AB_2678125, HPA043505: AB_2678518" "unprognostic (6.04e-3)" "unprognostic (2.81e-2)" "unprognostic (7.47e-2)" "unprognostic (2.84e-3)" "unprognostic (6.57e-3)" "unprognostic (2.00e-2)" "unprognostic (5.59e-2)" "unprognostic (2.43e-1)" "unprognostic (2.01e-1)" "unprognostic (1.72e-1)" "unprognostic (3.11e-1)" "unprognostic (1.51e-1)" "prognostic unfavorable (2.23e-7)" "unprognostic (1.37e-2)" "unprognostic (1.44e-1)" "unprognostic (1.67e-2)" "unprognostic (3.91e-2)" 9.1 0.6 12.3 1.4 12.0 1.8 0.9 11.1 30.7 2.1 7.1 1.9 2.0 0.7 1.5 23.3 1.7 1.8 2.4 11.4 16.6 4.0 11.5 2.0 0.9 13.0 14.5 0.7 68.6 1.4 1.9 0.8 16.9 1.3 0.8 1.1 5.1 1.0 68.4 1.6 1.4 0.8 12.6 0.9 14.8 0.7 17.6 0.5 1.5 11.7 3.0 4.3 3.7 16.6 9.1 6.0 1.5 27.2 4.3 3.2 11.1 53.5 109.5 5.8 15.5 15.1 2.2 2.8 4.1 4.8 17.2 6.0 12.0 4.4 4.1 10.4 2.5 2.5 1.6 0.0 80.7 7.3 0.1 36.1 130.8 17.1 23.2 1.8 5.4 62.3 7.7 12.5 4.8 5.5 5.3 0.1 4.9 31.0 21.3 4.8 0.1 12.8 3.0 3.5 5.3 7.9 1.6 9.5 95.0 3.3 3.6 51.1 1.8 1.3 16.1 1.5 9.4 81.1 19.0 11.0 4.8 10.3 12.7 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 12.3 12.0 11.1 30.7 11.4 16.6 13.0 14.5 16.9 12.6 17.6 16.6 6.2 0.0 2.0 0.3 3.1 2.8 3.8 11.5 3.4 2.6 2.2 2.4 4.6 4.3 6.5 0.0 2.1 0.3 2.6 8.0 35.2 6.4 0.1 1.8 0.4 2.7 3.5 3.2 1.3 27.8 0.3 0.6 33.6 2.1 0.0 0.4 1.8 0.7 0.4 0.0 1.5 8.0 6.1 0.3 1.5 0.0 0.3 0.8 5.4 0.0 1.0 0.5 0.0 0.5 0.2 19.3 2.3 0.0 21.4 6.5 0.8 0.3 3.3 0.4 0.0 0.3 3.2 1.1 1.1 1.5 4.3 3.4 1.6 0.5 4.8 14.6 CHCHD10 "C22orf16, MIX17A, N27C7-4" ENSG00000250479 "Coiled-coil-helix-coiled-coil-helix domain containing 10" Q8WYQ3 22 23765834-23767972 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1622.6;skeletal muscle: 1220.9" "Cell type enhanced" "Detected in all" "Distal enterocytes: 1264.7;Distal tubular cells: 2498.5;Hepatocytes: 1879.9;Proximal enterocytes: 1501.3;Proximal tubular cells: 1437.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003440 Enhanced Supported Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA003440: AB_1078348" "unprognostic (3.88e-2)" "unprognostic (2.36e-3)" "unprognostic (8.90e-2)" "unprognostic (9.80e-2)" "unprognostic (7.68e-2)" "unprognostic (5.97e-3)" "unprognostic (1.59e-1)" "unprognostic (1.85e-1)" "unprognostic (2.23e-2)" "unprognostic (2.40e-1)" "unprognostic (1.61e-1)" "unprognostic (5.13e-2)" "prognostic favorable (2.15e-7)" "unprognostic (5.19e-3)" "unprognostic (2.06e-1)" "unprognostic (5.68e-3)" "unprognostic (2.62e-3)" 216.5 136.5 181.6 30.3 188.3 12.5 144.5 183.0 248.9 77.3 262.6 261.2 92.6 35.5 32.4 147.3 43.1 10.9 1622.6 176.6 190.5 409.5 789.7 56.9 28.6 182.2 182.2 29.0 118.0 220.0 112.3 11.9 187.6 106.4 76.2 63.1 148.3 50.5 1220.9 71.8 159.0 17.9 169.5 100.3 160.2 27.8 204.8 14.0 224.7 660.7 34.5 110.2 89.1 179.3 33.1 66.4 19.7 85.9 42.1 27.7 41.9 11.9 22.8 23.5 28.4 124.1 35.1 113.5 30.7 41.2 12.9 99.8 109.2 34.1 20.5 35.9 140.6 22.5 48.8 117.1 73.8 63.6 108.2 53.3 91.9 35.6 9.3 4.9 29.0 17.2 47.7 48.0 20.6 121.8 21.8 48.2 16.9 194.9 183.5 90.0 4.0 209.0 112.7 55.3 41.3 23.8 13.9 145.7 149.7 36.6 54.9 47.0 15.3 1.0 1.1 18.3 0.2 28.8 11.1 62.5 20.5 54.9 11.2 0.2 4.1 11.2 3.0 9.1 1.9 11.7 3.2 4.0 1.8 10.6 4.9 3.5 0.0 0.8 8.2 7.3 4.3 1.2 181.6 188.3 183.0 248.9 176.6 190.5 182.2 182.2 187.6 169.5 204.8 179.3 88.7 12.8 10.5 36.2 294.8 48.2 415.4 28.2 144.5 136.2 156.9 238.2 503.8 268.8 20.5 419.3 114.7 42.5 104.7 1264.7 2498.5 88.1 27.0 76.6 229.8 47.4 310.5 74.3 38.5 54.5 255.7 67.8 300.7 94.3 84.0 171.9 78.1 1879.9 647.5 99.3 37.6 860.9 26.4 262.1 127.5 18.0 48.7 243.1 373.5 15.9 107.8 188.5 25.7 17.1 17.4 45.9 890.1 29.3 297.3 192.4 1501.3 1437.4 10.0 287.8 124.9 254.0 200.4 32.3 43.4 459.3 43.9 105.2 123.0 216.0 952.4 470.1 CHCHD2 "C7orf17, MIX17B, MNRR1" ENSG00000106153 "Coiled-coil-helix-coiled-coil-helix domain containing 2" Q9Y6H1 7 56101573-56106476 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Transcription Activator "Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A-431: 3195.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027407, HPA052510" Approved Supported Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA027407: AB_10959659, HPA052510: AB_2681856" "unprognostic (8.68e-3)" "unprognostic (2.79e-1)" "unprognostic (8.48e-2)" "unprognostic (2.32e-1)" "unprognostic (3.90e-2)" "prognostic unfavorable (1.90e-5)" "prognostic unfavorable (9.41e-5)" "unprognostic (4.38e-2)" "unprognostic (3.61e-1)" "unprognostic (2.30e-2)" "unprognostic (1.37e-1)" "unprognostic (2.79e-2)" "unprognostic (2.60e-2)" "unprognostic (4.01e-2)" "unprognostic (1.79e-1)" "unprognostic (2.09e-1)" "unprognostic (2.40e-2)" 250.6 665.5 321.4 167.4 331.8 426.3 253.9 361.8 358.5 220.7 351.0 257.6 252.0 219.0 252.4 269.6 210.6 132.1 412.4 325.3 352.7 349.4 316.7 213.8 205.0 340.1 341.5 246.3 315.9 322.9 272.3 151.8 343.2 237.2 191.7 226.2 281.2 196.7 791.4 233.3 243.9 150.5 354.6 223.3 287.6 120.7 352.2 267.7 208.2 591.3 200.2 217.8 214.2 367.9 3195.8 553.5 351.8 732.5 275.9 379.3 261.7 456.7 436.2 584.6 561.3 513.0 517.4 932.1 589.1 285.1 741.3 527.6 456.5 507.4 469.6 609.1 831.5 549.2 422.0 738.9 510.5 745.9 844.8 339.1 571.9 438.0 532.4 312.3 444.1 800.3 1182.9 546.7 486.4 449.9 1007.2 2306.5 760.6 867.3 872.6 668.3 343.3 1539.3 532.5 417.0 671.5 834.3 360.6 874.7 597.1 239.4 1002.5 1046.8 354.2 354.2 823.5 1473.9 683.6 497.1 785.4 1698.9 555.3 802.0 448.0 354.1 509.1 400.6 362.1 458.7 377.4 461.2 387.4 387.2 575.8 435.0 344.9 354.9 268.0 400.9 467.1 785.2 550.9 1066.7 321.4 331.8 361.8 358.5 325.3 352.7 340.1 341.5 343.2 354.6 352.2 367.9 465.1 256.4 284.0 44.4 521.9 717.5 956.6 1072.0 387.0 348.7 758.3 929.8 160.8 513.3 612.1 413.8 62.6 955.1 577.6 807.9 1860.7 1034.0 167.2 593.3 396.0 446.5 541.2 666.1 26.7 1325.1 1259.9 514.7 393.0 622.8 394.3 458.8 377.0 727.2 969.6 492.9 35.6 973.0 752.7 483.5 701.2 213.4 614.2 496.2 763.1 28.1 806.5 769.6 593.2 19.6 43.2 1190.3 974.5 505.9 803.3 1321.7 1138.5 1558.4 559.1 353.7 427.3 620.2 583.8 520.4 574.2 680.8 719.3 1228.8 492.5 633.1 929.0 1464.2 CHCHD3 "FLJ20420, Mic19, MICOS19, MINOS3, PPP1R22" ENSG00000106554 "Coiled-coil-helix-coiled-coil-helix domain containing 3" Q9NX63 7 132784870-133082090 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "heart muscle: 125.6;skeletal muscle: 351.7;tongue: 243.0" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 210.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042935 Enhanced Supported Mitochondria NA NA 13000 "Cluster 27: Non-specific - Gene expression" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA042935: AB_10794538" "unprognostic (1.53e-1)" "unprognostic (2.50e-1)" "unprognostic (4.15e-2)" "unprognostic (3.00e-3)" "unprognostic (5.69e-2)" "unprognostic (4.75e-3)" "prognostic unfavorable (3.25e-4)" "unprognostic (1.39e-2)" "unprognostic (1.28e-1)" "unprognostic (1.18e-1)" "unprognostic (1.69e-3)" "unprognostic (2.04e-1)" "prognostic favorable (1.15e-4)" "unprognostic (4.98e-2)" "unprognostic (1.20e-1)" "unprognostic (2.57e-1)" "unprognostic (8.03e-2)" 40.4 33.3 18.0 29.0 19.4 51.5 32.8 21.7 25.4 25.5 22.2 45.5 56.7 28.0 19.2 28.3 25.5 22.5 125.6 20.1 19.3 54.8 32.1 26.4 30.3 19.6 19.0 27.2 26.6 59.7 17.2 30.2 19.2 25.4 49.7 40.3 24.3 28.6 351.7 20.8 42.2 37.1 17.7 21.9 31.6 16.8 18.2 42.5 35.6 243.0 29.8 31.8 23.0 21.5 102.0 103.8 99.7 138.9 70.6 64.9 60.2 97.0 90.3 106.7 117.4 121.0 108.9 83.1 37.6 61.1 237.1 69.1 117.0 82.7 148.7 113.4 111.8 85.9 101.9 70.7 139.3 194.7 62.1 59.0 55.8 146.9 151.7 53.2 75.9 107.6 186.1 74.2 100.1 134.3 284.0 169.9 165.1 160.3 117.2 140.6 146.2 119.8 103.9 83.1 127.4 158.8 80.5 62.4 186.7 67.6 52.5 116.2 63.5 101.8 44.3 162.0 176.7 71.3 100.4 206.6 161.1 163.9 146.6 42.3 43.7 33.2 30.5 62.8 28.9 38.5 27.6 29.6 57.9 23.2 23.9 26.9 6.4 45.2 52.1 49.5 41.9 34.0 18.0 19.4 21.7 25.4 20.1 19.3 19.6 19.0 19.2 17.7 18.2 21.5 32.0 25.6 26.2 103.8 36.5 34.9 28.7 56.9 31.9 26.5 29.0 25.7 138.8 38.6 36.2 14.7 22.9 69.7 29.0 40.4 125.2 61.5 99.6 27.8 33.6 34.3 35.9 64.3 201.3 60.7 79.5 38.9 32.6 22.4 34.2 34.6 17.2 20.7 78.4 15.2 210.5 48.9 30.5 27.3 44.4 103.4 31.4 38.3 37.4 100.2 49.7 34.2 37.0 161.4 143.5 50.1 31.0 35.3 46.5 44.4 50.7 88.8 29.6 27.0 32.9 43.4 53.5 20.9 29.2 37.0 40.3 68.4 34.0 55.8 73.1 42.6 CHCHD4 "FLJ31709, MIA40, TIMM40" ENSG00000163528 "Coiled-coil-helix-coiled-coil-helix domain containing 4" Q8N4Q1 3 14112077-14124870 "Predicted intracellular proteins" "Protein transport, Translocation, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 84.1;Proximal tubular cells: 62.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA034688, HPA063727" Uncertain Supported Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA034688: AB_10696361, HPA063727: AB_2685103" "unprognostic (3.89e-3)" "unprognostic (8.82e-2)" "unprognostic (1.50e-2)" "unprognostic (7.34e-2)" "unprognostic (1.11e-2)" "unprognostic (9.12e-2)" "unprognostic (2.63e-3)" "unprognostic (1.02e-1)" "unprognostic (1.82e-1)" "unprognostic (5.55e-2)" "unprognostic (3.59e-2)" "unprognostic (1.43e-1)" "prognostic favorable (8.63e-5)" "unprognostic (1.53e-1)" "unprognostic (2.34e-1)" "unprognostic (9.65e-2)" "unprognostic (7.85e-3)" 12.2 14.0 12.3 8.6 12.9 3.3 11.5 12.8 16.4 9.8 13.3 19.5 14.6 8.9 10.1 12.4 9.6 5.8 25.8 12.4 14.4 20.9 18.8 7.6 8.9 13.0 13.8 10.4 11.1 22.9 9.6 8.5 13.0 10.8 15.5 11.4 10.1 11.8 34.1 10.3 11.5 8.8 12.5 10.3 13.6 8.7 12.7 9.4 9.6 29.0 12.7 15.1 9.9 13.3 19.1 39.2 19.8 19.8 16.9 18.9 57.5 20.3 18.7 24.4 21.4 23.3 15.3 40.9 19.4 15.5 24.7 15.3 41.5 41.8 29.8 25.7 41.6 47.9 28.5 31.3 28.2 32.5 19.9 16.6 43.5 40.0 63.5 17.3 27.7 32.4 50.6 35.6 26.3 40.7 41.0 19.6 30.6 59.5 52.1 29.3 19.9 87.5 27.8 20.7 16.3 20.1 22.6 72.2 30.1 17.0 34.6 32.8 10.0 22.3 16.2 27.8 37.4 19.8 56.1 40.6 21.9 49.5 16.6 12.0 15.6 10.7 7.8 24.0 14.0 15.0 13.2 12.1 25.7 22.0 16.8 11.5 6.9 21.8 24.8 10.5 16.3 11.6 12.3 12.9 12.8 16.4 12.4 14.4 13.0 13.8 13.0 12.5 12.7 13.3 6.7 16.0 8.6 2.9 10.6 9.4 14.5 17.9 13.1 7.9 13.3 11.4 24.5 11.5 8.8 9.2 0.0 21.6 3.5 12.2 84.1 18.8 2.6 6.7 8.3 9.0 4.9 20.8 3.2 13.4 22.3 8.9 5.6 5.4 10.8 7.6 3.9 20.4 21.0 5.0 3.8 13.3 16.2 10.0 6.6 5.3 11.5 9.7 8.8 1.9 11.4 9.9 15.5 2.5 3.5 13.1 10.0 10.1 13.2 25.3 22.4 62.2 5.9 7.2 6.6 9.9 11.8 24.7 40.4 20.8 11.8 13.0 7.3 12.0 17.9 11.6 CHCHD5 "C2orf9, MGC11104, MIC14, MIX14" ENSG00000125611 "Coiled-coil-helix-coiled-coil-helix domain containing 5" Q9BSY4 2 112584240-112589275 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038263 Approved Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 22: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA038263: AB_10671525" "unprognostic (3.56e-2)" "unprognostic (3.41e-2)" "unprognostic (3.36e-2)" "unprognostic (4.57e-2)" "unprognostic (1.85e-1)" "unprognostic (7.75e-2)" "unprognostic (2.72e-1)" "unprognostic (7.18e-3)" "unprognostic (8.04e-2)" "unprognostic (4.96e-2)" "unprognostic (2.07e-1)" "unprognostic (4.95e-2)" "unprognostic (1.39e-2)" "unprognostic (3.91e-2)" "unprognostic (2.36e-1)" "unprognostic (1.87e-1)" "unprognostic (1.12e-2)" 19.1 28.9 20.6 12.4 22.0 18.3 22.4 22.6 28.7 18.5 19.8 19.2 18.0 17.8 6.4 28.2 19.6 14.4 24.5 20.0 21.7 35.8 40.2 17.8 14.6 21.4 21.6 15.8 46.1 28.1 31.7 9.8 21.3 22.2 6.3 5.7 16.5 12.6 38.9 23.3 17.2 6.5 21.5 18.5 25.4 22.9 22.6 16.7 27.1 18.7 7.9 19.6 18.8 21.9 32.5 53.1 23.3 0.1 9.3 19.7 22.0 14.0 18.2 28.3 20.0 58.1 39.0 24.7 54.4 19.4 23.9 23.4 8.9 31.2 3.8 26.8 43.2 33.4 15.6 46.4 40.8 28.5 22.5 26.5 26.3 37.4 22.8 13.2 15.8 0.1 35.1 36.5 18.1 80.3 25.8 45.1 26.0 24.1 25.9 0.9 19.3 48.7 37.8 29.1 29.7 33.4 17.7 26.3 31.6 6.2 33.9 24.9 22.0 28.2 39.7 17.2 20.4 65.0 66.3 29.1 39.1 7.7 33.9 22.1 69.0 68.6 49.9 66.6 42.1 49.3 46.8 47.5 64.1 63.2 48.1 49.9 38.3 62.3 62.6 81.3 78.6 61.9 20.6 22.0 22.6 28.7 20.0 21.7 21.4 21.6 21.3 21.5 22.6 21.9 39.3 9.6 13.9 2.0 41.1 43.1 65.1 153.3 51.8 19.2 100.0 109.6 40.4 90.1 73.8 82.8 10.4 131.9 41.2 138.5 219.2 109.7 188.8 138.1 63.5 44.3 91.7 44.6 2.2 176.7 109.5 43.8 67.8 79.6 24.7 50.8 51.4 211.4 123.9 6.7 2.8 107.3 97.6 122.0 63.5 290.9 30.7 63.7 53.4 1.0 101.0 61.5 87.6 1.5 4.4 123.2 140.1 28.2 41.0 76.8 184.7 286.7 99.3 28.3 13.1 33.9 47.8 141.8 39.4 112.2 58.1 92.8 44.6 89.2 97.7 85.7 CHCHD6 "CHCM1, MGC13016, Mic25, MICOS25, PPP1R23" ENSG00000159685 "Coiled-coil-helix-coiled-coil-helix domain containing 6" Q9BRQ6 3 126704240-126960420 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 53.0" "Cell type enhanced" "Detected in many" "Hofbauer cells: 178.2;Late spermatids: 106.6;Melanocytes: 172.5;Spermatocytes: 119.7" "Cancer enriched" "Detected in all" 4 "melanoma: 34.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047673, HPA051975" Approved Supported Mitochondria NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 43: Testis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 4: Macrophages - Innate immune response" Mitochondria "HPA047673: AB_10961761, HPA051975: AB_2681679" "unprognostic (3.94e-2)" "prognostic favorable (7.46e-4)" "unprognostic (6.20e-2)" "unprognostic (1.91e-2)" "unprognostic (2.60e-1)" "unprognostic (1.16e-1)" "unprognostic (6.83e-3)" "unprognostic (1.87e-1)" "unprognostic (1.47e-1)" "unprognostic (1.31e-1)" "unprognostic (6.79e-2)" "unprognostic (2.08e-1)" "prognostic favorable (6.76e-4)" "unprognostic (6.47e-2)" "unprognostic (2.27e-1)" "unprognostic (2.79e-1)" "unprognostic (3.11e-3)" 9.4 12.8 22.2 3.8 24.7 4.2 10.8 17.7 34.3 13.1 16.4 11.6 3.9 11.5 5.0 10.9 13.7 5.0 11.9 35.0 22.7 14.4 7.4 10.7 3.9 19.0 21.6 17.7 14.8 15.6 16.5 4.1 21.0 10.5 3.0 8.3 14.1 7.8 4.7 16.3 6.2 5.4 18.4 6.9 11.7 53.0 21.4 4.9 13.0 3.2 2.9 11.1 11.5 22.1 37.1 21.1 18.4 44.7 6.4 9.8 10.5 14.1 9.5 16.0 15.5 29.3 15.8 16.3 31.8 8.5 17.5 21.3 13.9 38.3 7.9 4.5 37.7 13.5 15.8 29.0 19.0 29.2 8.5 9.9 22.9 7.8 16.3 13.1 10.6 28.4 12.2 9.4 14.2 27.7 43.2 29.1 22.3 20.9 23.7 22.8 28.0 38.9 14.3 15.8 33.6 21.0 14.5 24.3 45.4 9.0 14.2 10.8 9.7 17.9 22.2 24.5 14.6 12.0 5.9 20.4 20.1 9.6 17.0 0.0 2.4 2.1 6.8 4.1 8.8 8.4 9.9 8.4 6.8 11.6 9.4 11.2 0.0 7.7 3.7 4.8 10.0 4.6 22.2 24.7 17.7 34.3 35.0 22.7 19.0 21.6 21.0 18.4 21.4 22.1 8.9 19.2 12.5 20.5 7.1 29.6 21.7 35.5 9.6 15.4 20.0 31.5 18.5 8.6 24.0 14.7 18.8 40.8 3.4 6.4 58.7 22.7 99.0 18.6 8.8 7.3 7.7 8.2 48.1 24.2 12.1 14.8 9.7 5.8 14.0 45.6 6.8 7.2 178.2 20.2 45.1 10.8 28.5 10.1 15.6 106.6 15.8 33.0 172.5 12.2 2.7 20.2 2.1 22.6 22.0 18.9 9.0 22.2 7.1 29.6 2.6 27.9 56.1 16.1 0.0 10.9 17.9 119.7 51.4 16.0 30.1 15.5 8.2 14.1 13.3 21.1 CIBAR1 "FAM92A, FAM92A1, FLJ38979" ENSG00000188343 "CBY1 interacting BAR domain containing 1" A1XBS5 8 93698561-93731527 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "testis: 110.2" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 13.3;Extravillous trophoblasts: 14.1;Fibroblasts: 8.4;Hofbauer cells: 6.4;Syncytiotrophoblasts: 3.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034760, HPA058942" Enhanced Approved Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 68: Epididymis - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 33: Fibroblasts - ECM organization" Mitochondria "HPA034760: AB_10599947, HPA058942: AB_2732628" "unprognostic (2.65e-3)" "unprognostic (6.81e-2)" "unprognostic (2.48e-3)" "unprognostic (2.44e-1)" "unprognostic (1.62e-2)" "unprognostic (2.93e-1)" "unprognostic (3.56e-1)" "unprognostic (3.13e-1)" "unprognostic (1.20e-1)" "unprognostic (2.14e-1)" "unprognostic (2.28e-3)" "unprognostic (1.97e-1)" "unprognostic (1.71e-1)" "unprognostic (6.85e-3)" "unprognostic (1.97e-1)" "unprognostic (1.48e-1)" "unprognostic (3.07e-2)" 14.3 23.9 17.5 5.6 18.8 3.5 10.9 18.6 25.0 16.5 22.9 14.2 3.2 16.0 26.2 5.0 13.1 14.1 25.3 17.8 16.2 20.2 18.5 9.9 5.7 13.4 14.5 18.0 21.1 21.5 20.8 10.1 13.3 12.1 5.9 14.1 5.7 11.6 10.3 6.6 7.7 15.0 12.9 5.7 9.8 110.2 17.1 5.0 14.5 11.1 3.1 14.6 9.3 17.4 37.8 20.0 52.9 54.6 55.8 78.9 14.0 34.2 49.8 45.2 43.5 3.5 8.6 3.2 42.7 50.7 52.0 26.6 54.0 32.5 41.0 1.2 29.5 21.5 20.8 18.7 64.1 1.0 5.5 50.4 14.3 44.3 36.0 64.9 49.0 18.1 13.4 1.7 35.8 14.2 23.8 4.1 22.2 0.8 1.1 2.3 39.7 0.8 35.3 8.7 15.3 18.7 24.4 0.5 41.6 23.7 8.2 11.8 27.2 44.2 17.4 46.3 28.0 2.6 2.7 1.2 38.8 3.0 15.8 0.1 1.7 0.0 0.1 1.2 0.2 0.4 0.4 0.1 2.9 0.0 0.1 0.3 0.0 1.3 0.1 0.3 0.8 0.5 17.5 18.8 18.6 25.0 17.8 16.2 13.4 14.5 13.3 12.9 17.1 17.4 2.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 14.1 8.4 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 CISD1 "C10orf70, MDS029, mitoNEET, ZCD1" ENSG00000122873 "CDGSH iron sulfur domain 1" Q9NZ45 10 58269162-58289586 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 82.3" "Cell type enhanced" "Detected in all" "Distal tubular cells: 716.1;Proximal enterocytes: 539.1;Proximal tubular cells: 726.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074383 Supported Supported Mitochondria NA NA 13000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA074383: AB_2686684" "prognostic unfavorable (1.11e-4)" "unprognostic (8.60e-3)" "unprognostic (1.07e-1)" "unprognostic (4.10e-3)" "unprognostic (2.41e-2)" "unprognostic (3.22e-2)" "prognostic unfavorable (4.15e-4)" "unprognostic (1.87e-2)" "unprognostic (2.35e-1)" "unprognostic (7.78e-2)" "unprognostic (1.33e-2)" "unprognostic (7.23e-2)" "unprognostic (1.34e-3)" "unprognostic (4.19e-2)" "unprognostic (7.20e-2)" "unprognostic (8.07e-2)" "prognostic unfavorable (6.69e-4)" 5.2 10.1 10.0 6.3 9.8 0.9 5.9 10.4 13.6 6.6 11.8 9.7 22.7 5.6 3.4 11.2 6.1 7.2 43.0 10.1 12.7 26.4 16.6 4.3 6.1 10.1 9.9 6.8 5.3 82.3 5.8 5.5 11.2 7.6 8.8 8.2 9.9 7.1 46.4 8.4 21.8 8.0 9.5 4.6 7.2 2.8 9.6 6.5 10.1 49.9 5.9 7.8 3.0 8.9 20.5 10.2 8.0 14.6 10.5 11.6 4.7 16.9 19.2 16.4 22.5 24.1 18.8 36.1 13.9 17.5 9.6 12.9 21.7 15.1 14.7 16.2 29.4 9.5 16.4 19.6 11.9 17.0 7.1 14.6 12.1 15.7 23.9 13.9 19.5 17.9 21.2 16.5 11.6 6.8 14.6 18.2 8.5 15.5 31.4 11.0 29.3 19.0 22.1 7.1 25.0 9.0 12.9 34.1 12.4 7.0 22.7 9.0 19.3 7.1 12.8 20.5 20.4 16.6 29.0 27.2 18.9 16.6 7.0 0.0 4.5 0.2 4.3 3.4 5.3 6.3 4.9 5.0 7.6 5.4 5.7 5.7 2.3 5.4 2.3 5.0 6.8 4.2 10.0 9.8 10.4 13.6 10.1 12.7 10.1 9.9 11.2 9.5 9.6 8.9 31.4 60.9 45.7 27.4 33.0 128.7 87.3 309.4 78.0 84.6 46.4 61.1 321.6 97.2 180.2 134.3 43.8 174.8 22.7 71.1 716.1 98.0 240.9 42.8 30.4 61.6 225.4 24.8 47.2 82.1 78.5 52.7 38.2 43.8 34.3 23.0 63.9 249.6 68.6 42.1 53.1 141.9 272.6 37.0 37.9 366.1 42.3 31.0 183.2 21.5 34.0 47.2 44.3 36.7 30.9 83.2 121.9 40.3 31.7 109.1 539.1 726.8 138.6 56.3 32.9 50.1 55.6 159.4 65.6 94.9 114.2 72.7 26.2 65.0 147.3 69.4 CLPP ENSG00000125656 "Caseinolytic mitochondrial matrix peptidase proteolytic subunit" Q16740 19 6361531-6370242 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 229.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010649 Supported Supported Mitochondria NA NA 8500 "Cluster 20: T-cells - T-cell receptor" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA010649: AB_1078538" "unprognostic (2.28e-1)" "unprognostic (7.14e-2)" "unprognostic (2.82e-1)" "unprognostic (4.34e-2)" "unprognostic (2.17e-2)" "unprognostic (1.15e-2)" "unprognostic (6.17e-3)" "unprognostic (7.43e-2)" "unprognostic (2.76e-1)" "unprognostic (1.31e-1)" "prognostic favorable (6.50e-4)" "unprognostic (1.21e-1)" "unprognostic (5.65e-2)" "unprognostic (6.97e-2)" "unprognostic (1.83e-1)" "unprognostic (1.03e-1)" "unprognostic (5.86e-3)" 48.6 65.8 52.0 41.5 51.5 42.9 45.1 52.2 63.8 39.1 58.0 46.6 47.4 41.1 17.8 56.1 40.1 20.8 78.0 50.9 52.7 60.5 90.7 39.7 47.7 52.8 52.4 38.5 53.6 36.6 44.5 25.4 49.5 41.0 22.9 15.6 48.3 31.2 146.8 47.5 43.6 25.1 51.8 45.6 55.6 45.2 54.5 45.2 36.1 59.3 35.6 44.6 37.9 53.9 146.7 98.2 61.2 113.9 38.7 54.8 62.4 76.9 59.5 112.2 102.5 87.2 48.9 124.1 122.8 61.3 61.1 83.1 63.5 109.1 38.5 133.8 189.3 95.8 82.2 122.9 106.6 90.7 129.8 73.4 74.4 78.9 82.9 69.7 113.9 188.5 97.5 174.5 72.3 192.8 153.1 104.5 93.2 100.6 207.8 108.6 73.2 206.2 81.2 79.4 99.3 95.9 48.9 123.8 133.0 36.7 67.3 130.6 76.9 70.5 69.7 180.7 156.0 235.4 225.3 137.2 103.5 132.9 117.3 29.4 82.6 47.8 112.0 79.6 133.5 119.5 159.4 139.6 102.4 131.5 138.4 137.4 62.1 126.5 55.5 155.5 207.2 162.6 52.0 51.5 52.2 63.8 50.9 52.7 52.8 52.4 49.5 51.8 54.5 53.9 39.6 22.4 35.2 8.1 45.9 44.9 59.5 90.8 38.1 31.0 47.6 57.9 45.8 55.8 46.2 44.1 12.5 72.2 43.7 56.0 144.8 88.8 105.5 27.6 43.1 51.6 35.3 54.9 5.4 96.6 113.6 42.4 36.2 35.0 26.0 63.1 61.8 89.6 81.3 21.9 7.5 50.9 54.9 38.9 35.0 229.8 42.6 38.7 55.2 4.7 70.6 46.6 46.4 4.5 9.5 101.9 67.7 43.2 82.4 89.5 110.9 189.0 44.5 24.6 13.1 30.0 79.9 67.7 48.1 56.5 37.1 57.7 65.3 95.1 65.4 65.4 CMC2 "C16orf61, DC13, MGC45036" ENSG00000103121 "C-X9-C motif containing 2" Q9NRP2 16 80966448-81020270 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 263.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA006871, CAB026396" Approved Supported Mitochondria NA Yes "Cluster 15: NK-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB026396: , HPA006871: AB_1845581" "unprognostic (2.43e-1)" "unprognostic (3.63e-2)" "unprognostic (1.70e-1)" "unprognostic (3.52e-2)" "unprognostic (1.50e-1)" "unprognostic (3.01e-3)" "unprognostic (2.48e-2)" "unprognostic (6.36e-2)" "unprognostic (9.20e-2)" "unprognostic (3.84e-3)" "unprognostic (3.48e-2)" "unprognostic (4.57e-3)" "prognostic favorable (2.64e-5)" "unprognostic (1.08e-1)" "unprognostic (1.51e-1)" "unprognostic (1.17e-1)" "unprognostic (2.68e-1)" 22.1 24.6 47.6 14.0 50.0 45.2 17.0 49.0 60.2 17.2 41.2 22.7 19.1 12.4 16.6 20.4 11.6 17.0 68.4 48.4 50.7 43.5 44.0 24.3 22.4 47.6 47.6 13.7 27.3 30.4 26.1 16.3 47.5 34.9 16.9 16.1 14.8 12.4 54.0 15.3 20.3 15.0 48.3 21.7 27.2 47.0 51.2 30.1 16.2 33.9 17.1 20.7 17.0 54.2 74.8 103.1 76.1 43.7 25.1 25.0 44.9 73.4 33.1 64.0 32.9 71.7 49.9 33.5 53.3 35.8 62.9 52.6 52.5 42.8 84.9 50.9 63.3 51.9 68.4 78.6 40.6 43.5 85.4 21.8 23.8 77.7 43.5 29.2 57.1 83.1 124.2 43.5 63.3 140.1 68.1 138.4 45.2 59.7 62.0 84.2 41.2 43.8 50.4 35.9 64.1 37.1 110.6 39.8 87.3 39.4 78.7 39.2 32.8 57.9 82.0 56.6 75.3 45.4 107.6 193.8 44.6 55.3 69.1 33.2 28.0 37.3 28.8 29.6 27.5 39.1 36.5 30.1 31.6 34.9 25.3 29.2 12.0 44.6 34.2 45.3 64.4 18.0 47.6 50.0 49.0 60.2 48.4 50.7 47.6 47.6 47.5 48.3 51.2 54.2 41.2 35.3 38.8 48.0 54.9 97.6 75.5 53.9 48.9 31.9 48.0 50.7 204.7 42.9 36.5 47.8 54.2 44.8 78.9 29.5 158.5 34.4 95.4 44.2 33.7 36.0 38.3 55.5 88.6 38.0 62.8 45.0 42.8 45.2 95.5 37.3 25.4 86.0 51.4 30.3 62.2 42.9 59.0 70.5 84.1 168.3 24.5 59.7 65.8 14.0 33.8 29.3 51.5 48.7 74.0 39.0 31.9 29.3 83.5 69.1 48.5 166.1 31.4 16.7 59.2 33.3 47.0 263.5 121.5 65.0 102.1 38.0 84.7 55.3 44.8 74.4 CMC4 "MTCP1, MTCP1NB, p8, P8MTCP1" ENSG00000182712 "C-X9-C motif containing 4" P56277 X 155061622-155071136 "Disease related genes, Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 113.5" "Low region specificity" "Detected in all" HPA045866 Approved Supported Mitochondria NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 11: Alveolar cells - Smell perception" Mitochondria "HPA045866: AB_10964642" "unprognostic (4.54e-3)" "unprognostic (7.31e-2)" 14.5 11.5 15.1 9.3 17.0 8.2 12.2 17.5 17.7 13.3 14.8 17.0 12.5 12.4 16.7 11.2 11.8 10.6 52.6 14.3 16.6 15.1 23.3 8.4 15.0 18.0 16.5 15.2 32.7 12.7 11.8 8.2 17.0 12.8 7.0 7.3 18.9 12.6 31.8 10.8 10.1 7.9 16.6 9.7 11.8 8.0 16.0 6.8 14.1 24.5 8.4 12.4 11.6 17.9 63.7 16.6 9.5 19.8 24.5 23.6 14.2 12.0 17.5 16.7 28.3 10.2 11.1 40.7 30.8 13.9 48.0 20.5 11.8 16.2 10.8 45.5 30.7 6.2 10.2 13.5 25.2 12.8 9.3 22.8 24.9 16.7 20.2 15.9 13.3 25.3 6.2 15.2 17.1 23.5 17.2 23.8 5.6 25.3 42.5 14.6 20.9 28.5 18.3 4.2 19.0 14.4 16.0 17.9 20.3 10.9 13.3 8.1 17.3 26.1 16.9 16.4 16.8 62.9 67.3 113.5 23.7 29.5 16.9 2.0 12.9 22.2 14.8 7.5 15.3 19.1 11.9 14.3 19.6 18.6 3.5 9.5 1.2 23.1 3.0 3.8 15.1 8.3 15.1 17.0 17.5 17.7 14.3 16.6 18.0 16.5 17.0 16.6 16.0 17.9 3.9 0.0 4.1 3.3 1.9 0.8 1.1 2.6 2.8 1.0 3.4 5.0 0.0 1.5 6.0 0.0 0.0 1.0 3.9 0.9 3.9 1.5 0.1 2.4 2.7 1.8 1.8 7.8 1.6 0.5 1.0 2.8 2.0 1.4 5.1 2.5 2.2 4.7 1.0 0.0 2.3 0.8 0.0 1.3 2.6 1.4 3.7 1.9 1.8 1.9 1.0 1.4 2.1 2.5 4.6 0.7 1.2 1.9 4.0 0.5 2.0 4.1 4.8 0.3 0.0 1.2 2.0 1.4 0.8 4.2 2.4 1.2 2.9 1.2 1.6 0.7 COA1 "C7orf44, FLJ10803, MITRAC15" ENSG00000106603 "Cytochrome c oxidase assembly factor 1 homolog" Q9GZY4 7 43608456-43729717 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011944 Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA011944: AB_1848671" "unprognostic (1.16e-1)" "unprognostic (1.50e-1)" "unprognostic (2.22e-1)" "unprognostic (2.32e-1)" "unprognostic (1.42e-1)" "unprognostic (2.85e-3)" "prognostic unfavorable (7.84e-5)" "unprognostic (2.21e-1)" "unprognostic (4.42e-2)" "unprognostic (2.22e-2)" "unprognostic (5.22e-2)" "unprognostic (6.74e-2)" "unprognostic (1.52e-1)" "unprognostic (3.52e-1)" "unprognostic (1.02e-2)" "unprognostic (2.56e-2)" "unprognostic (5.39e-2)" 17.1 17.1 20.8 17.2 21.2 23.8 16.0 22.0 25.9 7.7 22.3 12.7 12.9 9.4 14.3 17.0 10.5 12.3 59.2 20.6 21.9 28.3 16.6 13.6 31.5 20.8 20.9 6.9 28.4 25.7 6.4 12.9 21.4 8.5 16.3 23.5 16.4 8.4 74.5 5.6 11.8 10.4 21.0 15.5 17.2 10.9 21.1 27.2 16.5 78.2 35.2 16.3 8.2 21.5 35.4 93.4 75.6 75.2 21.8 24.4 50.7 47.5 82.7 64.5 66.7 71.9 78.8 67.0 79.7 29.9 135.8 50.4 88.9 74.7 81.1 60.4 81.3 83.5 48.8 67.3 35.9 65.7 35.6 20.2 47.1 47.0 69.1 69.0 59.8 79.3 144.1 56.4 52.7 48.6 97.2 164.2 47.9 73.4 66.8 58.2 69.5 125.0 80.3 39.2 46.5 83.0 48.6 89.1 32.5 108.7 66.9 43.6 44.9 31.7 69.2 31.5 69.7 133.7 117.8 122.9 90.4 82.4 86.4 2.0 23.6 21.3 18.7 27.7 13.4 31.8 17.1 18.9 27.6 33.0 23.4 30.2 32.8 30.3 24.1 24.4 18.7 23.3 20.8 21.2 22.0 25.9 20.6 21.9 20.8 20.9 21.4 21.0 21.1 21.5 30.0 28.9 38.8 52.9 52.1 13.0 65.3 41.2 38.1 46.1 39.9 43.6 59.0 30.0 34.4 35.0 45.9 33.7 42.9 14.0 117.4 55.3 7.3 39.0 27.8 33.8 27.6 84.4 76.1 42.9 47.9 27.6 29.0 28.6 26.0 40.9 20.7 26.7 58.6 33.7 88.1 22.3 54.9 38.0 19.6 9.6 29.5 32.0 37.4 70.3 45.5 37.3 57.7 100.5 71.7 41.0 15.9 19.5 51.3 59.4 39.8 124.7 30.9 56.3 13.1 35.0 27.4 97.4 85.7 48.9 16.8 17.9 47.1 40.4 26.9 55.2 COA3 "CCDC56, COX25, HSPC009, MITRAC12" ENSG00000183978 "Cytochrome c oxidase assembly factor 3" Q9Y2R0 17 42795147-42798704 "Disease related genes, Predicted membrane proteins" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 710.2;Proximal tubular cells: 729.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031966, HPA071122" Approved Enhanced Mitochondria NA NA 13000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 22: Non-specific - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA031966: AB_10602115, HPA071122: " "unprognostic (1.20e-1)" "prognostic favorable (3.40e-4)" "unprognostic (5.65e-2)" "prognostic favorable (8.93e-4)" "unprognostic (7.62e-2)" "unprognostic (2.19e-1)" "unprognostic (4.78e-2)" "unprognostic (1.16e-2)" "unprognostic (1.48e-1)" "unprognostic (2.25e-2)" "unprognostic (8.44e-3)" "unprognostic (1.52e-1)" "prognostic favorable (6.62e-4)" "unprognostic (1.64e-1)" "unprognostic (2.70e-1)" "unprognostic (3.16e-2)" "unprognostic (3.01e-2)" 64.8 73.0 122.8 30.8 122.9 15.3 63.7 128.2 160.5 71.5 125.8 110.8 106.0 55.6 172.3 128.4 73.7 42.9 102.4 125.6 124.5 223.4 158.9 45.7 41.0 124.6 125.4 55.8 172.6 106.8 59.7 38.9 127.2 84.9 89.7 34.9 66.1 66.7 119.6 58.0 81.1 41.5 125.8 50.5 128.5 25.2 125.5 42.7 57.9 94.3 49.8 60.5 78.6 125.3 66.8 219.9 99.4 54.7 89.5 75.8 61.0 51.1 77.2 119.2 107.3 87.5 81.8 3.9 141.0 62.5 112.4 63.5 77.3 124.8 111.9 65.1 202.8 44.7 96.3 280.8 63.4 61.0 52.0 77.4 92.0 112.7 64.2 61.0 96.1 31.6 72.9 55.5 106.9 108.9 20.2 132.9 45.7 135.9 78.5 79.4 145.1 113.6 122.6 90.2 73.8 61.9 52.2 54.9 91.5 85.3 170.3 78.5 59.3 129.6 67.5 55.4 69.0 65.1 76.3 36.2 97.3 60.1 89.8 206.7 209.6 141.5 136.2 208.1 143.5 218.9 140.0 138.3 178.8 187.5 128.4 126.2 22.7 187.5 177.7 120.3 191.1 245.9 122.8 122.9 128.2 160.5 125.6 124.5 124.6 125.4 127.2 125.8 125.5 125.3 55.4 28.9 68.7 7.5 44.5 36.8 52.2 192.7 50.7 36.5 99.9 110.9 263.9 173.0 113.8 266.7 20.9 153.9 30.3 233.8 710.2 136.5 13.2 203.0 70.0 65.4 79.9 54.3 8.1 239.8 177.5 72.5 103.5 154.6 35.5 77.5 69.3 390.1 121.6 45.4 9.2 205.9 195.3 75.3 33.4 18.8 55.9 54.8 88.9 6.5 86.0 94.7 63.8 6.6 11.8 134.7 201.6 45.1 73.2 79.0 221.7 729.1 145.2 37.0 39.5 46.2 88.0 48.4 52.1 242.0 55.5 102.2 43.4 97.6 258.9 67.7 COA5 "C2orf64, FLJ27524, MGC52110, Pet191" ENSG00000183513 "Cytochrome c oxidase assembly factor 5" Q86WW8 2 98599314-98608515 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 180.0;Proximal tubular cells: 175.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057768 Uncertain Supported Mitochondria No No "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA057768: AB_2683521" "unprognostic (1.00e-1)" "unprognostic (4.19e-2)" "unprognostic (3.85e-2)" "unprognostic (1.67e-3)" "unprognostic (2.61e-2)" "unprognostic (7.11e-2)" "unprognostic (4.69e-2)" "prognostic favorable (2.65e-4)" "unprognostic (1.32e-3)" "unprognostic (3.71e-3)" "unprognostic (8.00e-3)" "unprognostic (3.08e-2)" "unprognostic (1.40e-1)" "unprognostic (1.29e-1)" "unprognostic (4.93e-2)" "unprognostic (2.50e-1)" "prognostic favorable (1.00e-5)" 14.9 20.9 39.7 10.4 40.9 9.7 18.5 46.0 46.0 19.0 35.6 21.4 14.7 18.5 29.8 11.7 19.2 11.0 21.2 40.1 40.4 26.6 22.8 12.9 16.3 40.7 40.8 21.2 15.6 22.0 23.5 13.4 40.6 19.8 14.4 38.4 15.1 17.6 28.5 16.8 17.7 12.4 40.3 19.4 17.8 12.9 42.6 17.3 22.5 22.0 15.5 18.1 14.1 44.1 18.5 7.9 24.4 17.5 28.1 22.6 20.4 10.6 8.5 11.4 11.8 16.3 15.1 9.6 18.4 8.7 21.7 13.1 21.2 11.5 13.8 24.5 18.5 13.3 15.2 26.0 20.4 13.1 11.6 22.7 23.6 8.1 10.5 19.7 12.0 26.6 18.6 10.8 12.4 14.6 17.2 22.9 16.9 19.8 16.7 10.4 17.2 21.1 24.8 9.9 18.4 23.1 9.1 11.3 27.6 27.4 13.9 26.4 11.1 17.2 15.3 10.4 9.0 17.6 25.0 12.0 21.0 28.0 14.5 20.2 24.9 29.4 23.9 23.5 20.3 23.6 21.0 22.5 24.0 25.3 25.5 25.5 28.0 20.1 25.8 31.2 31.1 22.9 39.7 40.9 46.0 46.0 40.1 40.4 40.7 40.8 40.6 40.3 42.6 44.1 39.5 16.0 28.7 10.4 27.3 10.5 26.3 46.5 28.5 25.5 45.5 62.6 66.6 37.1 32.6 47.8 6.2 36.9 34.8 26.3 180.0 43.4 28.0 52.8 30.4 30.6 27.0 29.4 12.0 24.5 38.8 29.8 21.9 35.6 26.6 33.3 31.8 63.6 52.8 21.9 12.4 37.2 59.0 38.1 12.5 14.9 32.6 30.5 28.4 4.7 41.3 51.4 54.6 8.5 19.1 30.8 29.6 35.0 24.0 34.4 46.1 175.0 49.2 32.0 13.1 23.5 29.7 118.4 33.8 32.5 11.6 32.7 23.5 46.1 33.2 33.6 COQ4 CGI-92 ENSG00000167113 "Coenzyme Q4" Q9Y3A0 9 128322544-128334072 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubiquinone biosynthesis" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 202.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021406, HPA042945" Supported Supported Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 49: Ciliated cells - Cilium organization" Mitochondria "HPA021406: AB_2670691, HPA042945: AB_10961047" "unprognostic (9.15e-2)" "prognostic favorable (2.97e-5)" "unprognostic (2.29e-1)" "prognostic favorable (4.93e-6)" "unprognostic (1.60e-1)" "unprognostic (1.46e-1)" "unprognostic (1.25e-1)" "unprognostic (1.04e-1)" "unprognostic (7.51e-2)" "unprognostic (2.11e-1)" "unprognostic (1.31e-3)" "unprognostic (2.89e-2)" "prognostic favorable (5.76e-6)" "unprognostic (6.21e-3)" "unprognostic (1.98e-1)" "unprognostic (1.42e-1)" "unprognostic (5.14e-3)" 23.9 52.9 33.9 21.7 35.3 19.7 28.2 32.9 43.6 31.8 43.1 35.9 76.7 24.9 19.4 62.1 51.8 21.5 39.6 34.8 37.8 62.9 63.8 25.0 24.4 33.4 33.9 30.5 64.1 45.5 53.4 17.6 33.2 41.2 23.7 22.3 47.1 28.3 31.8 56.4 54.1 15.4 32.3 27.5 39.5 22.6 34.3 20.3 51.2 22.6 22.9 31.1 34.1 36.0 36.6 54.4 31.5 36.6 22.4 31.2 58.2 31.7 20.6 40.1 28.0 48.4 46.5 48.6 28.1 24.2 31.6 99.9 27.0 38.0 14.6 25.1 50.5 18.1 112.9 52.9 38.9 51.5 27.0 37.4 45.2 33.6 36.6 21.9 32.4 40.8 121.1 31.5 26.0 106.2 60.5 38.0 37.0 75.1 60.7 60.7 45.2 91.0 49.0 36.9 58.8 40.1 64.7 71.5 41.4 13.8 92.2 18.0 43.3 38.0 35.1 56.9 43.9 53.4 50.4 38.5 47.4 25.0 28.1 22.6 31.1 19.0 44.1 36.4 39.8 39.9 39.4 44.1 39.6 34.4 31.1 38.2 3.8 35.5 37.2 63.7 34.5 29.9 33.9 35.3 32.9 43.6 34.8 37.8 33.4 33.9 33.2 32.3 34.3 36.0 21.3 22.4 29.0 25.8 31.9 28.8 47.1 75.1 47.3 29.9 60.2 65.9 43.0 42.9 48.9 57.0 27.1 90.3 36.5 70.3 142.8 56.4 15.3 139.7 39.8 25.4 31.8 36.0 23.9 63.4 47.5 32.1 35.7 42.2 36.8 37.1 30.0 77.4 49.8 30.3 26.3 65.6 57.0 26.7 23.9 27.4 30.1 24.0 40.9 8.4 27.2 37.4 27.8 17.1 28.8 46.1 66.2 30.9 60.8 32.8 185.3 202.4 161.9 53.3 26.3 27.9 33.4 47.2 31.6 79.4 50.0 47.2 32.3 69.3 85.5 58.0 COQ8A "ADCK3, CABC1, COQ8, SCAR9" ENSG00000163050 "Coenzyme Q8A" Q8NI60 1 226940286-226987544 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Ubiquinone biosynthesis" "Kinase, Transferase" "Disease variant, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "skeletal muscle: 1165.1;tongue: 484.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 21.9;Collecting duct cells: 33.1;Ductal cells: 21.2;Exocrine glandular cells: 32.7;Proximal tubular cells: 24.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 82.0;RPMI-8226: 78.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061662 Supported Mitochondria NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA061662: AB_2684578" "unprognostic (6.37e-3)" "unprognostic (2.09e-2)" "unprognostic (2.29e-1)" "unprognostic (9.06e-2)" "unprognostic (8.94e-2)" "unprognostic (2.49e-1)" "unprognostic (4.42e-2)" "unprognostic (3.50e-3)" "unprognostic (1.81e-1)" "unprognostic (4.02e-1)" "unprognostic (4.15e-3)" "unprognostic (8.67e-2)" "unprognostic (2.40e-2)" "unprognostic (9.24e-2)" "unprognostic (2.82e-1)" "unprognostic (8.88e-2)" "unprognostic (2.62e-1)" 63.9 123.8 7.1 10.3 8.0 26.1 35.8 17.3 8.1 16.5 16.1 30.8 29.9 15.9 0.5 32.2 24.6 19.7 123.5 7.1 5.6 14.4 35.7 9.6 12.7 8.9 5.4 34.1 93.8 6.4 5.3 6.5 9.8 18.5 6.4 1.3 32.7 11.7 1165.1 25.1 18.5 7.2 5.9 14.4 52.8 6.7 5.9 8.6 9.4 484.7 4.3 40.8 13.4 11.5 8.0 14.4 3.3 10.3 11.4 7.3 57.7 3.6 2.9 5.2 6.9 23.0 12.8 24.5 17.9 2.4 2.6 9.2 6.9 8.2 0.8 25.5 82.0 16.7 11.2 38.8 2.5 25.8 9.3 14.2 12.2 4.0 5.4 4.9 2.5 24.7 29.4 19.4 0.7 11.0 15.2 37.3 15.5 62.8 29.5 14.9 17.1 78.6 1.6 5.9 59.9 24.2 7.3 28.7 20.6 3.4 15.1 34.8 2.5 5.9 5.3 8.2 13.3 43.0 40.5 13.1 5.3 29.3 6.0 47.7 23.5 68.4 15.8 17.1 15.3 22.2 15.8 14.6 18.6 26.8 21.5 17.0 43.1 21.2 13.6 8.1 21.5 26.0 7.1 8.0 17.3 8.1 7.1 5.6 8.9 5.4 9.8 5.9 5.9 11.5 11.4 3.2 21.9 0.0 5.8 0.0 0.0 0.0 0.0 0.0 18.1 17.1 0.0 0.0 4.3 33.1 0.0 12.2 10.2 0.0 15.6 21.2 0.0 12.3 8.9 5.4 0.0 0.0 0.0 32.7 10.0 6.3 0.0 9.6 13.9 9.8 0.0 0.0 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 11.4 0.0 0.0 0.0 0.0 10.8 0.0 0.0 3.2 0.0 0.0 24.8 2.2 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 7.7 5.2 16.0 0.0 0.0 COQ8B "ADCK4, COQ8, FLJ12229" ENSG00000123815 "Coenzyme Q8B" Q96D53 19 40691514-40725784 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 16.5;Endometrial ciliated cells: 16.4;Theca cells: 19.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027229, HPA027277, HPA027279, HPA028303" Supported Enhanced Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 6: T47d - Mammary gland" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA027229: AB_10600100, HPA027277: AB_10599857, HPA027279: AB_10601219, HPA028303: AB_2672551" "unprognostic (7.57e-2)" "unprognostic (9.48e-2)" "unprognostic (1.61e-1)" "unprognostic (2.36e-2)" "unprognostic (2.33e-2)" "unprognostic (1.19e-1)" "unprognostic (1.79e-1)" "unprognostic (4.63e-2)" "unprognostic (1.85e-1)" "unprognostic (2.27e-1)" "unprognostic (2.82e-2)" "unprognostic (1.48e-1)" "unprognostic (2.93e-2)" "unprognostic (6.18e-2)" "unprognostic (1.46e-1)" "unprognostic (7.17e-2)" "unprognostic (2.65e-2)" 15.1 25.2 10.1 5.7 10.7 5.9 15.3 10.4 12.8 23.4 10.9 19.4 9.7 22.0 2.3 16.0 29.8 7.6 21.9 9.8 10.6 21.0 25.7 16.4 6.0 10.6 10.8 22.5 20.7 8.4 49.3 3.5 10.3 23.2 2.3 1.3 16.9 7.3 14.4 20.2 17.8 3.8 11.2 18.3 23.9 17.3 10.6 8.8 23.3 8.6 3.3 20.3 18.4 10.5 9.9 39.5 7.9 18.5 7.8 6.1 8.5 6.6 7.8 5.6 5.1 15.4 14.3 13.8 20.0 4.3 7.8 9.8 7.0 10.5 2.0 20.0 10.4 11.6 12.7 6.4 12.1 4.1 19.2 8.4 10.6 5.4 5.4 5.2 7.4 13.7 7.7 8.1 6.0 6.4 4.9 5.7 6.4 11.5 3.6 11.5 13.1 12.4 15.7 17.6 15.1 11.0 12.5 20.4 21.0 4.4 22.8 17.1 9.4 5.1 20.6 3.9 5.5 9.4 9.0 7.3 27.8 5.2 9.1 10.2 9.4 8.7 6.7 9.3 8.3 7.1 5.5 7.8 9.9 5.9 4.6 5.1 9.0 6.9 9.2 4.6 4.9 7.3 10.1 10.7 10.4 12.8 9.8 10.6 10.6 10.8 10.3 11.2 10.6 10.5 8.5 12.8 3.9 0.0 1.2 0.0 0.0 0.0 0.0 0.0 11.6 8.0 0.0 0.0 2.5 12.9 0.0 11.1 6.8 0.0 11.7 16.5 0.0 16.4 7.8 1.7 0.0 0.0 0.0 10.9 9.8 5.0 0.0 10.3 1.3 11.7 0.0 0.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 9.5 0.0 0.0 1.2 0.0 0.0 13.0 8.7 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 9.4 3.2 19.8 0.0 0.0 COX14 "C12orf62, MGC14288" ENSG00000178449 "Cytochrome c oxidase assembly factor COX14" Q96I36 12 50112082-50120457 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 835.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044618, HPA062014" Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA044618: AB_10960419, HPA062014: AB_2684657" "unprognostic (5.71e-2)" "unprognostic (1.86e-2)" "unprognostic (1.43e-1)" "unprognostic (4.04e-1)" "unprognostic (1.87e-2)" "unprognostic (3.66e-2)" "unprognostic (2.20e-2)" "unprognostic (4.20e-3)" "prognostic unfavorable (7.90e-4)" "unprognostic (7.02e-2)" "unprognostic (1.52e-2)" "unprognostic (6.34e-2)" "unprognostic (7.09e-3)" "unprognostic (3.24e-1)" "unprognostic (1.90e-1)" "unprognostic (1.84e-2)" "unprognostic (3.07e-3)" 124.0 106.4 96.3 47.1 101.4 66.2 105.6 110.3 129.7 63.6 120.1 92.4 83.4 46.2 130.5 68.5 54.9 62.9 238.6 94.5 105.5 143.8 145.4 62.3 74.5 102.6 99.8 52.8 62.0 127.8 88.0 54.7 102.9 67.0 77.5 60.6 84.9 80.7 247.6 49.8 84.0 58.7 102.9 66.9 76.5 32.6 104.0 54.9 87.3 276.7 62.0 74.2 47.3 110.2 78.4 168.3 32.8 79.4 169.4 105.7 60.5 61.1 92.7 98.8 89.5 156.7 109.1 69.9 171.9 78.3 82.6 79.0 57.2 87.5 91.7 78.7 236.6 154.3 140.4 139.2 65.1 112.1 133.7 123.8 129.9 67.1 76.7 100.5 96.2 83.1 70.2 153.4 109.1 193.3 93.7 170.3 51.5 116.4 211.3 77.6 52.4 176.8 155.0 149.1 91.0 51.4 92.4 177.5 195.6 72.6 115.1 103.6 75.2 55.0 58.1 92.3 50.1 106.3 199.0 93.5 77.9 105.0 30.9 258.8 197.8 172.7 146.1 194.5 155.6 213.7 186.9 167.0 190.0 188.0 176.7 173.7 67.0 153.1 178.2 247.2 224.8 214.8 96.3 101.4 110.3 129.7 94.5 105.5 102.6 99.8 102.9 102.9 104.0 110.2 91.5 60.9 120.6 11.1 108.8 124.9 91.2 212.9 87.0 68.2 169.2 192.5 524.4 161.5 138.7 222.5 22.9 191.9 111.1 320.9 565.4 131.4 7.1 117.5 58.7 99.2 156.0 69.2 13.1 170.1 122.6 90.3 81.6 88.1 65.4 64.0 88.9 397.9 219.6 47.1 16.3 214.7 187.2 152.3 110.4 22.9 129.2 117.7 149.4 6.5 181.2 111.0 111.2 7.1 22.3 116.8 262.4 109.4 93.0 129.5 492.6 835.5 157.5 67.4 105.2 51.5 130.8 51.1 56.0 121.6 159.3 127.5 112.2 115.4 227.4 118.6 COX16 "C14orf112, HSPC203" ENSG00000133983 "Cytochrome c oxidase assembly factor COX16" Q9P0S2 14 70325081-70416984 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 302.9;Ionocytes: 187.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062659 Uncertain Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Mitochondria "HPA062659: AB_2684823" "unprognostic (5.44e-2)" "unprognostic (1.31e-1)" "unprognostic (2.68e-1)" "unprognostic (1.21e-2)" "unprognostic (3.63e-1)" "unprognostic (6.37e-3)" "unprognostic (1.80e-2)" "unprognostic (8.22e-2)" "unprognostic (1.88e-1)" "unprognostic (1.73e-2)" "unprognostic (6.80e-2)" "unprognostic (7.44e-2)" "prognostic favorable (1.03e-12)" "unprognostic (4.08e-1)" "unprognostic (1.73e-1)" "unprognostic (3.97e-1)" "unprognostic (1.72e-1)" 19.4 27.1 20.2 18.2 19.9 22.8 27.8 20.4 29.2 16.5 22.9 26.6 30.2 12.8 27.1 17.1 17.3 19.4 24.4 20.1 20.7 29.3 40.5 16.7 21.7 21.0 20.1 17.2 43.5 26.9 12.7 14.3 20.5 20.7 22.1 24.3 21.9 13.7 84.0 17.5 26.7 10.5 20.2 18.9 33.4 17.7 20.2 20.8 23.3 44.5 19.0 19.3 12.6 22.5 100.2 31.2 65.9 56.0 26.7 36.0 48.3 55.0 37.1 38.9 34.7 19.2 93.5 26.2 36.6 33.8 33.5 41.8 27.6 35.5 48.9 18.9 27.5 36.9 31.3 22.1 16.1 35.9 48.7 36.1 25.1 24.0 23.0 41.5 34.2 69.2 20.8 54.6 39.0 49.6 85.4 43.8 68.3 83.3 44.5 57.6 53.2 37.0 46.2 49.0 57.8 46.0 46.2 102.4 53.9 42.2 87.4 69.1 42.5 50.2 111.6 55.4 40.6 57.6 38.9 48.2 75.4 19.1 61.1 48.6 33.8 8.0 24.2 38.0 29.2 45.7 34.5 29.1 36.3 39.8 32.3 34.8 2.5 45.6 38.3 55.7 43.6 44.0 20.2 19.9 20.4 29.2 20.1 20.7 21.0 20.1 20.5 20.2 20.2 22.5 22.0 51.3 53.9 0.0 45.0 84.4 9.4 302.9 70.6 8.2 29.7 18.8 7.1 32.9 162.2 23.9 2.1 14.8 22.9 23.8 52.8 47.1 2.7 43.6 21.3 28.5 31.2 46.0 0.0 64.8 20.2 36.0 99.4 62.1 33.5 7.4 31.8 57.7 18.2 1.7 0.0 35.8 187.2 34.6 89.3 4.6 18.3 40.0 96.0 0.0 26.3 25.2 25.7 0.0 0.0 59.1 27.0 15.8 99.3 11.2 42.5 48.6 137.1 10.0 6.6 13.6 27.5 15.4 21.0 125.7 100.7 10.9 39.8 7.3 39.4 14.4 COX17 ENSG00000138495 "Cytochrome c oxidase copper chaperone COX17" Q14061 3 119654513-119677454 "Cancer-related genes, Predicted intracellular proteins" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA042226, HPA048158" Supported Supported Mitochondria NA NA 220000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" Mitochondria "HPA042226: AB_2677911, HPA048158: AB_2680292" "unprognostic (1.98e-2)" "unprognostic (3.49e-2)" "unprognostic (1.96e-2)" "unprognostic (8.29e-2)" "unprognostic (2.88e-2)" "unprognostic (6.63e-3)" "unprognostic (3.49e-2)" "unprognostic (2.90e-1)" "unprognostic (1.36e-1)" "unprognostic (7.11e-3)" "unprognostic (2.12e-1)" "unprognostic (4.45e-2)" "unprognostic (1.33e-2)" "unprognostic (2.15e-2)" "unprognostic (1.65e-1)" "unprognostic (9.19e-2)" "unprognostic (2.64e-2)" 81.6 178.5 106.5 77.1 111.2 113.3 68.8 117.5 122.4 50.3 149.2 90.2 90.2 41.2 114.1 55.9 47.3 59.4 279.9 105.5 123.6 94.7 172.7 62.3 110.4 115.8 115.3 31.5 102.0 412.1 119.2 63.9 115.7 78.6 78.7 120.6 80.8 90.7 401.4 43.3 88.5 62.9 112.5 64.9 107.5 44.4 113.0 106.6 94.4 363.9 89.8 75.9 35.7 118.6 219.6 257.0 122.7 33.3 53.4 53.1 45.7 130.5 84.2 127.3 133.4 226.4 157.7 164.6 158.0 72.1 174.8 84.0 138.5 154.9 74.9 205.5 155.9 145.0 195.3 180.1 63.1 205.0 246.7 56.6 142.7 77.9 106.0 82.2 87.9 200.8 122.4 370.7 155.4 410.2 212.8 283.5 133.8 212.2 413.3 88.3 82.3 273.7 203.2 141.0 210.5 86.4 153.1 137.1 189.7 76.9 180.5 313.0 66.6 91.3 144.9 59.8 168.4 257.5 348.9 361.1 129.0 157.8 164.2 591.4 241.1 630.6 218.1 357.5 208.1 378.3 241.7 230.3 252.8 320.4 189.1 187.0 174.4 213.6 487.3 538.7 352.6 260.1 106.5 111.2 117.5 122.4 105.5 123.6 115.8 115.3 115.7 112.5 113.0 118.6 194.5 157.0 167.1 5.2 161.5 94.1 132.8 267.9 46.7 108.9 153.8 147.2 622.8 238.8 202.4 498.4 43.8 137.4 116.7 385.3 716.1 264.0 115.0 282.4 64.3 164.7 214.2 162.9 3.8 413.7 193.9 99.3 150.3 178.8 309.3 70.2 116.0 779.8 216.1 75.7 5.6 327.8 427.2 181.8 281.2 39.9 91.0 190.8 277.5 11.2 345.7 178.8 137.0 8.5 8.8 459.7 512.8 136.9 176.5 198.2 434.6 786.2 280.2 174.4 184.1 112.9 171.6 286.0 159.2 85.4 125.4 211.0 129.0 49.6 151.1 199.0 COX20 "FAM36A, FLJ43269" ENSG00000203667 "Cytochrome c oxidase assembly factor COX20" Q5RI15 1 244835616-244845057 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 414.8;Proximal tubular cells: 464.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043617, HPA045490" Approved Enhanced Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA043617: AB_10965694, HPA045490: AB_10962869" "unprognostic (5.84e-3)" "unprognostic (1.20e-1)" "unprognostic (7.33e-2)" "unprognostic (2.86e-1)" "unprognostic (3.62e-1)" "unprognostic (3.70e-2)" "unprognostic (1.07e-1)" "unprognostic (1.62e-1)" "unprognostic (1.03e-1)" "prognostic favorable (3.13e-4)" "unprognostic (1.99e-1)" "unprognostic (6.38e-2)" "unprognostic (3.44e-2)" "unprognostic (2.54e-2)" "unprognostic (3.70e-2)" "unprognostic (3.10e-1)" "unprognostic (7.02e-3)" 17.5 44.2 28.1 23.3 30.9 20.1 22.1 37.4 49.2 13.9 23.6 23.9 24.3 24.8 29.9 21.5 17.2 15.3 42.9 27.9 30.1 50.2 29.6 15.8 21.4 30.3 30.3 35.4 23.2 22.8 11.1 17.7 28.8 28.7 18.7 58.3 17.1 18.6 43.3 15.2 25.0 20.5 29.2 15.0 23.1 25.0 29.3 16.3 37.0 37.4 16.5 20.4 9.6 30.1 132.6 34.1 33.5 100.4 22.5 17.3 75.2 54.0 35.7 31.0 27.2 93.9 88.9 21.3 65.7 36.6 58.3 36.1 17.8 43.0 40.8 56.0 15.6 38.6 47.6 85.7 28.7 95.7 57.5 16.0 20.2 44.5 30.8 44.9 35.2 22.7 81.2 80.2 63.0 33.0 53.5 43.5 84.2 94.9 68.6 38.5 42.0 121.5 59.5 33.1 19.6 54.2 68.1 36.1 79.6 32.1 67.0 28.7 69.3 67.3 88.7 59.9 120.1 128.0 188.7 43.7 90.9 108.2 65.3 14.5 15.3 21.4 27.1 36.4 26.3 34.2 31.3 30.2 26.5 32.6 21.2 28.7 3.9 24.2 34.5 26.1 43.4 20.4 28.1 30.9 37.4 49.2 27.9 30.1 30.3 30.3 28.8 29.2 29.3 30.1 66.7 19.2 52.1 44.1 77.7 85.1 115.1 144.3 38.1 111.5 104.4 110.1 68.6 183.0 90.5 191.3 45.9 231.5 74.4 97.7 414.8 154.1 38.6 78.4 74.1 61.4 61.8 82.0 16.6 188.9 164.6 56.1 57.6 119.5 73.4 53.1 42.5 294.8 122.1 89.2 24.4 91.7 77.3 64.8 79.6 75.9 69.6 73.4 72.9 9.4 97.6 195.2 110.2 27.6 34.1 178.6 87.0 80.1 51.9 75.9 134.8 464.0 67.7 133.4 65.7 83.2 85.0 67.1 122.4 61.6 75.6 264.5 81.4 63.6 115.3 87.8 COX4I1 "COX4, COX4-1" ENSG00000131143 "Cytochrome c oxidase subunit 4I1" P13073 16 85798633-85807068 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Oxidoreductase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002485, CAB004080" Supported Supported Mitochondria NA NA 55000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB004080: AB_2085427, HPA002485: AB_1078559" "unprognostic (4.73e-2)" "unprognostic (9.14e-3)" "unprognostic (2.65e-1)" "unprognostic (6.18e-3)" "unprognostic (2.47e-1)" "unprognostic (4.52e-2)" "unprognostic (2.65e-1)" "unprognostic (1.46e-1)" "unprognostic (5.97e-2)" "unprognostic (7.82e-3)" "unprognostic (3.32e-2)" "unprognostic (2.29e-1)" "prognostic favorable (2.56e-8)" "unprognostic (4.23e-2)" "unprognostic (4.06e-1)" "unprognostic (1.01e-1)" "unprognostic (2.38e-2)" 473.1 393.5 874.4 232.5 881.4 583.2 437.1 896.5 971.9 373.1 882.6 690.5 585.9 301.8 478.8 597.2 355.8 246.9 2047.0 869.5 909.5 632.7 611.2 318.6 412.8 896.4 891.1 366.2 490.4 900.7 362.1 256.7 908.6 377.1 707.7 261.2 421.2 312.3 1333.3 552.5 529.5 301.4 877.2 405.9 650.3 191.1 922.9 479.9 361.5 2063.3 538.7 422.6 420.9 881.0 433.7 677.7 460.2 616.8 823.6 761.2 785.7 379.6 771.2 702.3 346.7 1170.2 636.6 698.6 454.2 610.5 389.9 855.1 657.2 765.3 622.2 238.7 678.1 392.9 554.8 1093.8 741.9 362.9 282.0 893.1 1162.8 579.2 786.0 739.1 746.4 563.6 672.3 280.4 602.5 1510.6 730.9 1116.7 623.0 954.1 796.3 816.9 287.5 616.7 1066.7 840.2 543.2 441.1 807.4 513.2 656.2 489.6 753.2 996.6 529.9 355.5 409.5 330.7 419.0 561.4 562.5 1646.3 542.4 702.2 410.6 633.9 1373.2 805.2 700.3 1199.6 868.1 1302.9 930.5 833.2 1480.8 1231.2 1169.3 968.8 513.9 840.6 1089.3 1105.6 1106.1 2815.9 874.4 881.4 896.5 971.9 869.5 909.5 896.4 891.1 908.6 877.2 922.9 881.0 552.0 275.7 398.1 45.1 925.3 1129.4 1242.3 2031.6 1121.8 280.2 1365.2 1553.2 3479.9 1086.6 942.3 632.7 131.3 1223.1 714.3 1863.5 2752.8 1091.1 539.4 480.5 468.0 629.7 1009.6 524.6 44.0 1316.2 1094.7 591.2 813.0 575.6 521.4 554.3 660.7 1314.7 1602.3 212.0 51.7 1782.5 1125.0 1488.5 1376.5 1155.4 498.9 1010.5 1145.5 35.6 1451.7 562.9 785.8 35.7 65.5 1463.7 1950.7 357.7 726.2 1370.7 3811.3 2936.3 545.4 349.9 355.0 481.8 678.0 358.6 321.7 1721.9 1361.7 1481.9 816.5 1020.3 2147.9 1941.7 COX5B ENSG00000135940 "Cytochrome c oxidase subunit 5B" P10606 2 97646062-97648383 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1151.3;skeletal muscle: 1332.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 3614.3;Distal tubular cells: 3621.5;Proximal enterocytes: 2795.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034517 Supported Enhanced Mitochondria NA NA 230000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA034517: AB_10603561" "unprognostic (4.61e-2)" "unprognostic (4.33e-2)" "unprognostic (1.71e-1)" "unprognostic (1.26e-1)" "unprognostic (1.39e-1)" "unprognostic (1.92e-2)" "unprognostic (2.48e-1)" "unprognostic (1.01e-1)" "unprognostic (1.86e-1)" "unprognostic (2.72e-2)" "unprognostic (1.79e-2)" "unprognostic (4.20e-2)" "unprognostic (4.02e-2)" "unprognostic (3.32e-1)" "unprognostic (1.01e-1)" "unprognostic (1.34e-1)" "prognostic favorable (2.73e-4)" 209.1 252.9 323.0 42.8 339.7 113.3 178.7 373.1 436.0 138.1 349.2 322.6 164.2 124.6 72.3 284.6 136.9 32.6 1151.3 319.2 357.2 478.6 372.8 120.4 40.3 341.7 339.9 138.4 165.6 234.0 169.0 47.1 339.9 158.2 113.4 74.5 196.7 90.1 1332.7 213.2 211.9 51.1 332.9 153.2 290.6 101.2 353.1 64.4 185.0 705.9 54.3 179.8 179.1 355.3 144.9 165.5 106.8 169.7 115.9 105.8 428.3 180.0 100.8 118.3 130.5 459.9 148.7 240.8 377.3 116.5 188.4 217.9 117.5 181.8 56.4 188.7 493.2 324.2 166.6 559.8 220.3 310.6 231.2 193.8 161.6 113.4 91.2 125.4 104.4 187.8 243.6 115.5 94.0 360.0 203.5 450.0 196.6 257.2 854.3 194.9 170.6 368.8 167.5 227.9 202.2 210.3 175.0 225.0 374.8 146.0 115.7 345.5 186.9 107.5 181.4 174.4 118.7 265.8 274.7 183.1 194.9 264.5 113.5 1086.6 1062.7 933.1 458.0 1057.0 445.1 801.5 547.4 481.8 990.1 666.0 528.0 468.8 1016.6 469.6 926.3 677.6 783.4 1543.0 323.0 339.7 373.1 436.0 319.2 357.2 341.7 339.9 339.9 332.9 353.1 355.3 461.0 221.2 256.0 33.3 292.7 386.6 629.5 1166.0 377.9 239.1 433.2 536.2 3614.3 567.6 618.5 800.0 227.2 736.0 257.4 1960.0 3621.5 599.5 207.5 399.4 300.8 380.0 740.3 308.8 27.3 604.1 897.1 391.6 616.7 439.7 330.6 392.2 361.3 1234.9 875.0 141.3 33.7 1430.5 1043.6 485.2 651.9 360.8 351.6 456.6 912.4 30.0 711.7 461.5 314.1 15.6 39.4 505.4 1836.0 304.6 353.3 468.2 2795.9 2663.5 485.4 386.3 447.0 340.2 569.9 265.2 310.7 944.2 479.9 613.2 291.9 455.7 1576.9 915.9 COX6A1 COX6A ENSG00000111775 "Cytochrome c oxidase subunit 6A1" P12074 12 120438090-120440737 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" Oxidoreductase "Charcot-Marie-Tooth disease, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062394 Approved Supported Mitochondria NA NA 85000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA062394: AB_2684749" "unprognostic (1.18e-1)" "unprognostic (1.03e-2)" "unprognostic (5.10e-2)" "unprognostic (6.16e-2)" "unprognostic (1.47e-1)" "unprognostic (8.78e-2)" "unprognostic (3.33e-1)" "unprognostic (1.34e-1)" "unprognostic (1.09e-1)" "unprognostic (1.13e-2)" "unprognostic (3.22e-2)" "unprognostic (2.82e-1)" "prognostic favorable (6.50e-7)" "unprognostic (2.53e-1)" "unprognostic (1.31e-1)" "unprognostic (5.48e-2)" "unprognostic (2.63e-2)" 353.0 396.5 1004.7 203.3 1040.0 368.0 321.3 1052.0 1305.8 265.4 959.8 597.1 611.5 248.1 273.9 582.2 248.6 231.3 263.9 1030.7 1086.0 664.3 707.1 269.0 273.3 1062.6 1045.6 207.4 373.0 986.0 344.2 193.5 1075.6 282.7 443.1 392.4 373.3 244.3 59.7 372.2 481.2 230.4 995.3 262.3 493.9 224.4 1086.7 327.9 316.1 88.5 255.3 319.6 348.8 1046.6 532.7 1142.5 627.4 653.5 475.4 403.9 755.8 327.1 447.7 585.1 497.2 1388.3 528.9 1115.9 955.5 477.1 442.6 865.0 624.6 737.3 382.3 663.5 1314.3 596.5 594.9 1036.8 434.6 661.9 405.9 487.3 895.5 531.3 632.3 477.0 505.0 801.0 602.9 337.1 494.2 1528.7 965.1 1667.1 566.1 1034.6 1627.5 644.7 414.7 1044.5 945.3 1302.6 822.4 708.6 595.6 589.9 803.5 347.1 1051.4 742.9 373.0 355.0 431.9 370.9 466.8 513.0 791.3 897.5 558.7 643.2 484.9 225.6 347.3 316.4 258.9 353.6 278.9 377.1 305.3 287.3 486.9 296.9 279.3 287.3 297.9 253.7 374.0 516.7 460.6 534.3 1004.7 1040.0 1052.0 1305.8 1030.7 1086.0 1062.6 1045.6 1075.6 995.3 1086.7 1046.6 346.4 397.4 312.4 41.1 355.0 383.3 526.3 1145.7 508.2 238.3 411.3 426.7 124.4 543.3 683.0 774.3 577.6 774.8 289.0 1306.7 1481.1 659.4 207.3 487.3 239.6 311.2 515.7 348.0 26.3 661.9 701.5 304.0 437.3 425.9 272.2 263.9 266.0 971.0 779.3 146.4 38.1 861.7 980.6 376.6 426.0 136.4 302.0 377.7 524.7 19.7 583.9 440.8 332.7 23.6 56.9 726.1 1417.1 265.5 565.2 506.1 1857.6 1701.6 718.9 414.2 341.8 259.0 508.6 455.8 373.7 1155.8 388.0 927.2 341.0 399.5 1049.7 778.9 COX6B1 "COX6B, COXG" ENSG00000126267 "Cytochrome c oxidase subunit 6B1" P14854 19 35648323-35658782 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 2453.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 2710.8;Distal tubular cells: 2985.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004192 Supported Supported Mitochondria NA NA 150000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA004192: AB_1847180" "unprognostic (5.12e-2)" "unprognostic (1.86e-2)" "unprognostic (3.81e-2)" "unprognostic (1.22e-1)" "unprognostic (1.62e-2)" "unprognostic (1.32e-1)" "unprognostic (2.18e-1)" "unprognostic (6.16e-2)" "unprognostic (3.52e-1)" "unprognostic (4.80e-2)" "unprognostic (1.64e-1)" "unprognostic (1.88e-1)" "prognostic favorable (5.42e-4)" "unprognostic (2.10e-2)" "unprognostic (6.98e-2)" "unprognostic (5.74e-2)" "unprognostic (5.48e-3)" 322.3 211.6 733.9 206.6 741.0 465.2 371.1 780.8 935.9 291.0 758.1 598.9 427.0 197.2 633.9 410.0 329.7 245.8 1284.7 749.3 761.3 519.5 582.3 201.7 316.0 768.3 740.1 241.1 292.4 850.2 169.9 222.3 757.0 249.2 690.0 276.5 356.6 328.6 1467.0 264.7 351.3 342.8 735.4 193.3 336.8 107.0 759.7 426.3 270.5 2453.4 510.5 402.2 205.1 747.2 480.3 1219.5 479.2 649.4 665.5 701.3 455.3 383.4 641.0 684.8 686.4 1018.3 478.0 555.8 663.1 656.6 413.4 341.7 836.5 700.6 683.5 632.0 570.1 929.4 626.6 1014.1 521.1 835.0 454.9 800.2 906.5 619.5 361.1 606.3 690.4 577.8 616.9 783.0 714.9 1019.4 589.2 626.8 357.0 2445.6 811.5 502.1 525.9 930.4 1567.1 1035.9 434.4 484.5 615.9 1049.3 393.4 568.5 419.6 892.9 365.9 363.8 398.0 382.3 605.6 450.5 683.3 776.7 470.9 695.0 472.7 1138.1 1099.7 998.5 628.9 1228.5 607.0 1150.2 854.9 732.8 1140.2 956.3 839.9 744.3 1115.9 672.8 1178.4 1176.1 1138.3 2058.8 733.9 741.0 780.8 935.9 749.3 761.3 768.3 740.1 757.0 735.4 759.7 747.2 324.6 243.6 227.3 27.4 409.4 427.1 436.6 1071.1 373.3 143.5 498.4 615.2 2710.8 664.8 529.6 698.9 64.6 623.0 361.5 1496.0 2985.6 711.7 328.0 427.4 293.2 312.6 625.7 436.5 21.2 808.9 735.5 360.9 484.2 397.2 280.8 277.9 338.8 1270.7 1041.1 89.2 27.9 1277.1 736.5 800.2 705.9 942.4 327.7 582.7 748.8 18.7 807.7 351.1 435.6 16.1 31.6 863.0 1445.3 273.1 523.2 548.7 2291.0 2228.5 445.5 193.3 263.0 293.8 454.2 175.7 186.6 784.8 565.6 670.7 373.1 229.1 1277.5 717.0 COX6C ENSG00000164919 "Cytochrome c oxidase subunit 6C" P09669 8 99873200-99893707 "Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014295, CAB016244" Enhanced Supported Mitochondria NA NA 210000 "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB016244: AB_2085703, HPA014295: AB_2668966" "unprognostic (4.91e-2)" "unprognostic (2.90e-2)" "unprognostic (6.90e-2)" "unprognostic (3.37e-2)" "unprognostic (1.58e-2)" "unprognostic (1.26e-1)" "unprognostic (1.63e-1)" "unprognostic (2.07e-2)" "unprognostic (1.29e-1)" "unprognostic (3.51e-1)" "unprognostic (3.70e-1)" "unprognostic (8.86e-2)" "unprognostic (3.47e-3)" "unprognostic (1.10e-1)" "unprognostic (5.31e-2)" "unprognostic (1.07e-1)" "unprognostic (6.99e-3)" 134.0 147.5 180.8 52.9 183.9 152.6 125.7 186.1 291.0 166.4 190.2 268.1 334.8 194.0 175.6 197.3 189.5 20.4 781.6 191.8 195.6 254.9 328.5 108.4 71.1 186.0 188.4 161.9 107.3 101.7 159.5 89.9 189.2 162.6 110.4 147.0 108.1 58.1 666.1 121.4 172.3 42.7 182.4 122.9 180.0 170.8 192.7 44.8 129.1 554.1 51.5 188.7 148.6 188.9 137.6 57.8 63.8 251.3 140.0 100.5 103.1 44.5 42.7 30.1 34.3 54.7 284.5 326.8 320.1 70.1 47.7 176.4 36.4 363.3 51.0 60.5 89.1 684.6 66.9 160.4 88.9 319.3 201.9 95.1 475.3 26.0 56.4 129.2 45.1 103.8 49.8 571.1 51.6 134.2 337.9 289.6 117.9 205.5 127.7 381.0 21.2 320.6 453.4 713.3 191.8 115.2 30.9 654.2 351.5 65.0 461.7 201.1 40.1 220.4 286.0 235.8 63.8 140.7 126.3 209.6 310.2 128.2 200.8 345.8 134.7 114.1 177.8 210.5 189.0 209.7 270.6 193.5 212.9 189.8 319.7 294.9 16.6 187.7 266.5 301.9 272.7 252.9 180.8 183.9 186.1 291.0 191.8 195.6 186.0 188.4 189.2 182.4 192.7 188.9 527.8 403.8 485.1 29.7 382.1 490.8 493.5 1431.9 279.4 217.6 561.3 642.7 2146.4 491.8 731.2 605.1 102.2 978.9 416.1 1263.2 2226.5 673.6 834.3 579.3 778.7 436.9 807.5 400.2 27.6 849.4 853.9 502.0 440.4 551.9 362.5 219.3 384.1 1855.5 1066.5 156.5 33.5 1221.3 1027.4 451.1 539.5 266.5 664.8 440.8 732.8 23.4 778.0 545.0 449.0 22.6 32.1 808.6 1338.7 587.5 412.2 448.4 2173.5 1791.0 702.9 282.0 493.0 367.1 555.9 1180.5 505.2 666.4 640.6 1784.9 452.1 428.0 1246.7 715.5 CPOX "CPO, CPX, HCP" ENSG00000080819 "Coproporphyrinogen oxidase" P36551 3 98579446-98593648 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Heme biosynthesis, Porphyrin biosynthesis" Oxidoreductase "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 352.8;Extravillous trophoblasts: 75.9;Oligodendrocytes: 99.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "HEL: 166.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015736, HPA054448" Supported Mitochondria No No 170000 "Cluster 26: Non-specific - Mitochondria" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" Mitochondria "HPA015736: AB_1847194, HPA054448: AB_2682490" "unprognostic (2.14e-1)" "unprognostic (1.04e-1)" "unprognostic (4.07e-2)" "unprognostic (6.09e-2)" "unprognostic (2.71e-1)" "unprognostic (2.34e-2)" "unprognostic (8.58e-3)" "unprognostic (7.14e-2)" "unprognostic (2.53e-2)" "unprognostic (2.01e-1)" "unprognostic (1.10e-2)" "unprognostic (1.86e-2)" "prognostic unfavorable (1.04e-5)" "unprognostic (1.62e-1)" "unprognostic (2.67e-2)" "unprognostic (2.15e-2)" "unprognostic (2.57e-1)" 8.1 10.0 19.7 11.4 28.2 44.1 7.2 24.0 31.7 9.1 13.5 10.0 21.2 10.1 7.2 16.1 7.4 8.1 8.6 19.5 22.4 6.5 35.3 7.5 12.3 30.8 24.9 10.7 7.2 9.5 5.4 18.0 29.8 8.4 12.0 4.5 7.6 7.9 11.2 13.1 15.2 9.0 24.5 9.5 9.4 4.7 25.1 12.8 7.1 9.8 12.3 8.1 10.9 41.8 47.9 22.9 19.9 35.4 36.5 26.9 56.6 30.0 21.7 30.7 34.7 38.2 14.7 5.0 33.1 16.2 33.6 34.1 24.9 32.8 51.9 15.4 21.6 166.4 12.9 49.9 18.5 35.7 37.8 21.2 27.0 29.0 12.0 35.9 29.6 20.2 32.2 20.9 29.1 14.8 36.2 30.4 23.4 26.6 41.0 25.4 45.0 22.1 26.2 19.8 13.1 13.0 32.0 10.9 96.2 22.1 16.7 22.5 24.9 45.1 44.0 26.1 22.4 31.6 26.8 26.7 44.6 38.3 33.7 0.0 0.6 0.0 0.3 0.3 0.7 0.5 0.6 0.8 0.5 0.5 0.2 0.8 0.0 0.6 0.2 0.3 0.3 0.2 19.7 28.2 24.0 31.7 19.5 22.4 30.8 24.9 29.8 24.5 25.1 41.8 6.4 3.2 8.7 9.1 5.6 7.4 3.9 7.3 11.4 4.3 6.0 4.6 8.0 7.2 4.2 3.7 8.4 23.9 6.5 7.9 1.9 3.7 0.1 5.2 8.6 7.4 8.4 352.8 17.7 1.7 75.9 9.4 10.2 5.0 1.3 7.0 11.7 36.4 12.7 0.0 12.3 9.1 4.1 11.3 10.0 0.2 7.5 11.4 12.4 11.2 12.7 5.8 3.1 13.0 99.1 3.2 4.1 7.9 10.4 5.2 9.4 6.3 5.0 5.0 13.1 6.4 7.2 0.3 6.1 12.2 10.2 10.7 12.7 9.7 9.9 4.2 CPT1A "CPT1, CPT1-L, L-CPT1" ENSG00000110090 "Carnitine palmitoyltransferase 1A" P50416 11 68754620-68844410 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Transport" "Acyltransferase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 110.0;Hepatocytes: 108.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008835 Supported Supported Mitochondria NA NA 45000 "Cluster 2: Granulocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA008835: AB_1078563" "prognostic unfavorable (3.84e-4)" "unprognostic (1.38e-3)" "unprognostic (3.04e-3)" "unprognostic (2.46e-2)" "unprognostic (1.45e-1)" "unprognostic (7.25e-2)" "unprognostic (2.17e-1)" "unprognostic (4.99e-2)" "unprognostic (2.72e-1)" "unprognostic (1.47e-2)" "unprognostic (2.92e-2)" "unprognostic (2.34e-1)" "prognostic favorable (2.67e-7)" "unprognostic (9.76e-2)" "unprognostic (1.06e-1)" "unprognostic (1.49e-1)" "unprognostic (2.46e-3)" 24.3 27.7 16.0 22.3 18.4 38.9 22.7 20.2 17.3 20.4 32.0 67.4 70.7 25.1 7.3 22.0 25.4 27.7 25.4 14.7 17.7 38.4 67.9 25.3 15.9 20.6 22.0 18.3 23.6 27.6 14.3 18.4 19.3 20.3 44.6 22.6 26.0 21.9 9.9 17.0 71.3 34.9 15.9 27.4 35.6 13.5 22.1 14.0 15.4 14.3 12.3 18.7 18.0 13.9 29.4 50.9 7.3 48.6 31.2 28.0 2.1 22.9 18.8 17.7 3.6 2.0 96.0 0.1 82.2 60.4 62.2 93.5 63.9 13.6 5.3 46.8 6.3 71.5 52.3 24.0 46.4 41.9 82.6 29.2 6.6 35.5 21.4 24.1 63.5 28.2 7.6 56.8 16.5 83.6 34.4 73.7 0.8 149.7 53.2 94.7 1.2 127.1 41.7 71.7 1.0 31.8 63.0 119.9 20.2 4.8 107.4 40.0 64.5 38.3 0.9 77.7 33.5 43.9 60.1 29.2 40.3 30.3 42.8 8.2 6.6 9.5 7.3 7.7 4.2 1.9 4.4 4.4 4.4 2.0 2.7 5.5 3.2 4.9 6.7 10.4 2.8 2.7 16.0 18.4 20.2 17.3 14.7 17.7 20.6 22.0 19.3 15.9 22.1 13.9 44.4 38.5 28.8 35.6 13.5 9.4 11.0 9.0 28.5 4.8 9.6 7.6 25.5 22.8 18.0 23.9 64.6 15.9 39.3 110.0 19.6 13.8 14.7 33.2 22.6 30.4 16.2 30.9 5.6 9.5 3.9 16.6 31.1 56.7 29.7 23.0 40.7 108.3 15.7 1.7 5.7 48.9 10.2 39.1 11.5 43.9 9.6 24.6 0.0 28.1 31.4 12.7 23.7 7.1 1.7 8.5 43.4 32.0 28.6 9.6 83.4 11.8 23.8 43.0 39.5 18.3 21.1 14.5 10.0 14.8 7.7 7.8 24.0 17.3 67.4 9.2 CS ENSG00000062485 "Citrate synthase" O75390 12 56271699-56300391 "Citric acid cycle related proteins, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Tricarboxylic acid cycle" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 550.1;tongue: 600.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 239.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038460, HPA038461, CAB075750, CAB075751, CAB075752, CAB075753, CAB075754" Enhanced Enhanced Mitochondria NA NA 670000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "CAB075750: AB_2665756, CAB075751: AB_2665757, CAB075752: AB_2665758, CAB075753: AB_2665759, CAB075754: AB_2665760, HPA038460: AB_2676023, HPA038461: AB_2676024" "unprognostic (7.67e-3)" "unprognostic (3.80e-1)" "unprognostic (2.59e-2)" "unprognostic (2.50e-2)" "unprognostic (2.70e-2)" "unprognostic (1.25e-1)" "unprognostic (6.09e-3)" "unprognostic (3.34e-2)" "unprognostic (2.43e-1)" "unprognostic (5.58e-2)" "unprognostic (2.56e-1)" "unprognostic (1.97e-2)" "prognostic favorable (1.17e-4)" "unprognostic (1.20e-1)" "unprognostic (2.09e-1)" "unprognostic (1.30e-2)" "unprognostic (2.02e-1)" 154.2 93.6 29.2 61.7 30.0 111.0 66.3 33.7 49.9 55.4 40.5 110.1 97.7 56.4 32.2 95.6 58.3 42.4 319.3 30.9 34.6 86.6 39.0 58.0 67.2 39.4 32.0 56.0 61.5 127.6 28.9 45.7 39.4 59.0 124.1 128.9 73.7 60.5 550.1 70.5 81.2 77.5 22.5 49.0 66.5 24.4 41.0 69.4 53.0 600.7 106.1 70.2 58.2 31.6 168.9 176.8 141.6 198.2 188.4 173.8 93.3 136.9 132.0 231.1 160.6 271.2 158.2 322.9 128.2 172.6 99.3 182.1 396.8 200.8 234.9 109.3 200.2 222.9 136.1 261.4 107.3 288.4 166.6 188.2 201.6 182.4 232.0 202.2 268.6 163.7 233.2 193.7 214.7 160.8 229.8 121.9 117.5 128.0 247.8 222.3 167.1 247.6 166.2 194.6 189.3 125.2 175.2 251.7 157.7 137.5 297.6 174.3 178.3 127.1 165.3 167.4 147.4 124.5 200.4 206.2 120.4 206.4 119.5 59.6 73.3 205.7 47.0 93.0 61.9 60.6 56.5 45.1 119.3 51.8 59.2 47.9 31.3 51.6 94.0 65.6 63.4 71.2 29.2 30.0 33.7 49.9 30.9 34.6 39.4 32.0 39.4 22.5 41.0 31.6 14.5 16.0 39.5 32.3 31.6 39.0 23.5 26.9 46.7 22.8 38.3 29.7 239.9 15.7 21.5 12.9 62.6 18.5 24.1 66.9 35.2 32.5 6.6 25.1 31.5 27.2 16.9 36.0 21.5 45.1 31.3 25.8 42.3 53.5 27.9 21.3 18.9 29.7 34.3 10.1 24.6 43.9 20.3 39.4 35.0 4.8 20.2 34.6 10.6 9.4 44.8 16.7 16.5 18.6 18.8 44.6 35.7 19.9 46.7 33.1 50.4 22.0 14.9 38.3 13.1 27.8 38.2 29.7 25.8 74.8 52.1 16.8 25.8 32.0 71.3 34.5 CTU2 "C16orf84, NCS2" ENSG00000174177 "Cytosolic thiouridylase subunit 2" Q2VPK5 16 88706483-88715396 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "tRNA processing" "Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041135, HPA041894" Uncertain Supported Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 35: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA041135: AB_10794543, HPA041894: AB_10796463" "unprognostic (4.19e-1)" "unprognostic (3.62e-2)" "unprognostic (5.19e-2)" "unprognostic (5.77e-2)" "unprognostic (3.00e-2)" "unprognostic (5.96e-2)" "prognostic unfavorable (5.68e-4)" "unprognostic (4.83e-2)" "unprognostic (1.56e-1)" "unprognostic (4.43e-2)" "unprognostic (1.19e-3)" "unprognostic (2.90e-2)" "unprognostic (1.25e-2)" "unprognostic (3.03e-2)" "unprognostic (5.83e-2)" "unprognostic (1.13e-1)" "unprognostic (1.74e-1)" 9.7 9.6 8.8 5.0 8.7 6.2 8.8 7.9 13.8 10.2 6.5 9.9 4.2 11.6 2.0 8.7 9.5 3.5 11.8 9.1 7.5 9.7 12.5 7.9 6.1 9.6 8.1 10.5 11.3 3.6 11.3 3.2 8.5 8.8 1.6 1.4 8.0 3.7 19.1 8.7 7.6 3.4 7.5 9.4 9.6 10.9 8.2 4.0 10.3 5.4 3.4 9.9 8.1 10.5 14.9 22.9 8.8 19.4 7.3 7.5 21.8 15.2 11.4 16.6 8.1 27.2 14.0 21.7 19.8 9.8 7.8 14.7 14.8 14.9 4.5 6.8 44.6 14.9 9.8 27.8 12.4 15.1 10.8 8.5 10.8 13.1 13.9 6.0 14.1 13.1 56.5 6.3 6.3 40.0 42.0 34.9 13.7 12.9 36.9 33.0 6.6 23.4 5.8 5.8 29.0 14.0 24.2 4.6 9.7 5.3 13.8 15.6 15.9 17.5 22.1 19.2 16.8 19.4 10.5 61.7 15.1 32.1 19.6 1.1 5.5 0.0 7.3 6.9 6.0 5.5 6.6 7.3 6.8 5.8 6.4 5.5 0.4 7.5 6.0 6.4 4.1 4.2 8.8 8.7 7.9 13.8 9.1 7.5 9.6 8.1 8.5 7.5 8.2 10.5 6.5 0.0 4.4 2.3 10.0 13.8 12.2 7.8 5.2 12.5 7.3 7.2 2.5 10.0 7.8 1.8 6.2 11.0 15.7 8.4 11.7 8.8 12.1 4.0 7.1 6.6 5.4 3.8 2.9 13.6 16.2 8.6 11.2 4.9 0.0 9.9 3.6 6.7 9.9 13.5 2.3 7.1 4.1 1.9 4.0 7.0 8.1 6.7 5.4 1.0 5.0 4.4 7.2 0.5 2.7 8.9 8.2 9.8 15.5 17.2 9.6 7.8 4.7 8.7 0.0 8.9 11.1 25.6 25.7 6.5 10.7 8.1 9.5 10.8 10.5 8.9 CYC1 UQCR4 ENSG00000179091 "Cytochrome c1" P08574 8 144095039-144097525 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 730.0;tongue: 724.9" "Cell type enhanced" "Detected in all" "Distal tubular cells: 817.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 1125.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001247 Supported Approved Mitochondria NA NA 45000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA001247: AB_1078602" "unprognostic (3.07e-2)" "unprognostic (1.79e-1)" "unprognostic (1.65e-1)" "unprognostic (3.66e-2)" "unprognostic (1.25e-1)" "unprognostic (6.52e-2)" "unprognostic (1.39e-1)" "unprognostic (3.92e-3)" "unprognostic (6.23e-2)" "unprognostic (1.98e-1)" "unprognostic (2.26e-1)" "unprognostic (2.15e-1)" "prognostic favorable (5.89e-6)" "unprognostic (6.03e-2)" "unprognostic (1.83e-1)" "unprognostic (2.13e-1)" "unprognostic (3.13e-2)" 84.7 173.2 92.1 62.4 97.2 104.4 72.7 115.4 103.8 71.4 102.4 162.6 171.2 75.9 35.7 155.5 67.8 39.5 527.7 92.3 105.3 152.6 180.4 56.7 55.8 99.8 96.9 63.6 101.2 163.3 58.2 45.8 103.1 67.8 111.0 42.0 104.4 70.0 730.0 106.5 127.5 59.9 94.9 70.1 139.6 38.9 106.9 63.4 64.8 724.9 61.0 92.0 86.5 99.6 172.0 381.4 98.9 208.4 80.5 88.5 189.6 96.7 116.7 240.2 156.9 269.4 208.2 241.0 210.8 129.8 116.2 247.3 217.9 191.2 89.8 148.2 289.2 259.7 306.5 250.4 143.1 154.7 162.5 129.4 234.9 153.2 301.4 80.6 141.3 163.7 240.4 208.2 127.7 616.8 292.0 143.5 115.1 476.8 1125.5 253.7 132.4 422.1 199.7 273.0 263.3 117.2 267.8 365.7 200.0 54.0 302.5 233.2 108.8 152.1 321.6 169.6 299.7 229.1 179.7 183.8 193.2 261.9 198.4 185.7 340.4 95.7 131.6 360.4 139.8 208.7 108.1 141.5 444.1 180.3 104.9 134.6 32.7 187.8 278.8 251.0 158.2 397.1 92.1 97.2 115.4 103.8 92.3 105.3 99.8 96.9 103.1 94.9 106.9 99.6 77.0 19.2 29.3 23.5 94.0 156.1 191.9 394.8 62.6 113.6 110.7 102.6 402.3 181.6 156.0 79.1 81.3 263.6 61.7 516.1 817.8 239.9 81.2 59.1 68.1 88.0 146.4 130.6 14.4 289.1 257.1 102.8 144.8 60.2 59.7 89.2 62.4 239.4 246.3 87.5 21.6 390.4 272.6 104.8 139.4 88.6 88.9 101.4 179.7 12.2 208.4 115.2 92.7 12.1 17.5 290.6 332.5 90.7 149.9 237.9 570.0 468.6 86.1 100.9 72.3 109.4 250.6 83.1 116.7 212.9 163.7 236.8 63.8 197.5 602.6 258.3 CYCS "CYC, HCS" ENSG00000172115 "Cytochrome c, somatic" P99999 7 25118656-25125260 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Electron transport, Respiratory chain, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 799.8" "Cell type enhanced" "Detected in all" "Distal tubular cells: 1663.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004222, CAB005126, CAB018597" Enhanced Supported Mitochondria NA NA 170000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria "CAB004222: AB_627385, CAB005126: AB_2090472, CAB018597: AB_627383" "unprognostic (3.06e-2)" "unprognostic (3.39e-1)" "unprognostic (3.32e-2)" "unprognostic (4.11e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (2.81e-4)" "unprognostic (4.44e-2)" "unprognostic (7.04e-3)" "unprognostic (5.67e-2)" "unprognostic (6.22e-2)" "unprognostic (2.41e-1)" "unprognostic (1.52e-1)" "prognostic favorable (1.30e-5)" "unprognostic (1.18e-1)" "unprognostic (4.94e-2)" "unprognostic (8.75e-3)" "unprognostic (7.04e-2)" 86.0 115.6 65.8 89.2 70.4 85.0 59.2 79.8 101.7 45.3 87.6 263.6 150.1 42.3 41.5 105.9 43.0 52.9 476.8 72.1 82.8 174.6 115.7 54.3 63.8 71.0 72.9 48.1 38.5 226.2 57.0 43.0 69.4 54.3 238.8 153.9 58.0 60.1 483.7 47.6 120.1 91.1 70.2 48.0 108.1 61.1 83.4 74.0 74.6 799.8 89.4 119.8 60.1 71.7 336.4 185.1 195.0 273.7 108.7 83.1 199.6 314.4 128.0 229.2 264.5 307.4 222.2 383.8 152.9 138.5 678.3 385.8 396.5 295.0 401.2 115.0 179.1 318.6 208.9 218.7 170.2 739.0 271.1 111.2 257.5 230.9 492.9 99.4 209.5 232.2 597.1 397.9 246.0 155.1 408.6 284.4 365.1 746.3 343.0 282.1 235.3 364.5 360.9 322.5 392.6 190.3 164.5 689.0 267.9 338.7 359.5 436.6 152.8 209.3 383.3 329.8 591.8 401.4 507.3 860.5 281.0 526.4 606.7 65.3 56.2 42.8 68.0 106.0 82.5 102.5 62.2 71.6 105.7 90.0 58.6 70.2 8.2 73.3 96.8 81.5 87.5 83.0 65.8 70.4 79.8 101.7 72.1 82.8 71.0 72.9 69.4 70.2 83.4 71.7 244.3 83.3 118.6 42.4 337.6 689.8 818.3 698.5 237.9 163.1 210.6 179.6 770.0 144.4 314.2 183.9 77.2 192.6 304.4 827.5 1663.0 278.3 496.4 154.8 120.2 183.3 384.9 162.6 53.2 216.0 351.0 257.3 287.5 197.5 212.6 68.7 81.0 210.8 353.0 132.9 64.6 522.5 502.5 141.5 715.2 161.8 90.1 329.2 590.5 16.9 245.8 220.9 197.8 17.1 24.2 303.8 570.5 93.6 358.7 551.9 392.8 638.6 146.1 195.2 138.1 294.7 962.3 423.1 211.1 402.7 715.2 349.3 349.7 146.9 600.2 884.1 CYP11B1 "CPN1, CYP11B, FHI, P450C11" ENSG00000160882 "Cytochrome P450 family 11 subfamily B member 1" P15538 8 142872356-142879846 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroidogenesis" "Monooxygenase, Oxidoreductase" "Congenital adrenal hyperplasia, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 877 "adrenal gland: 3686.5" "Group enriched" "Detected in some" 113 "Early spermatids: 53.3;Late spermatids: 83.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049171, HPA049565, HPA056348, HPA057752" Supported Approved Mitochondria NA NA "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "HPA049171: AB_2680661, HPA049565: , HPA056348: AB_2683104, HPA057752: AB_2683516" 0.2 3686.5 0.1 0.9 0.6 0.0 0.1 0.0 0.1 0.2 0.5 0.2 0.0 0.2 0.0 0.4 0.2 0.0 0.4 0.3 0.0 0.9 0.5 0.3 0.0 0.1 0.1 0.3 0.5 0.0 0.4 0.0 0.0 0.3 0.0 0.0 1.4 0.0 0.2 0.2 0.2 0.0 0.0 0.3 0.4 4.2 0.0 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 83.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CYP11B2 "ALDOS, CPN2, CYP11B, CYP11BL, P-450C18, P450aldo" ENSG00000179142 "Cytochrome P450 family 11 subfamily B member 2" P19099 8 142910559-142917843 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism, Steroidogenesis" "Monooxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 603 "adrenal gland: 179.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049171, HPA049565, HPA056348, HPA057752" Supported Uncertain Mitochondria NA NA "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 43: Cardiomyocytes - Nuclear processes" Mitochondria "HPA049171: AB_2680661, HPA049565: , HPA056348: AB_2683104, HPA057752: AB_2683516" 0.0 179.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CYP19A1 "ARO, ARO1, aromatase, CPV1, CYAR, CYP19, P-450AROM" ENSG00000137869 "Cytochrome P450 family 19 subfamily A member 1" P11511 15 51208057-51338601 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Cancer-related genes, Disease variant, FDA approved drug targets, Pseudohermaphroditism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "placenta: 124.4" "Cell type enriched" "Detected in some" 10 "Syncytiotrophoblasts: 2007.5" "Cancer enhanced" "Detected in single" "glioma: 0.6" "Group enriched" "Detected in many" 4 "amygdala: 4.8;hypothalamus: 4.1;medulla oblongata: 1.4;midbrain: 2.0;thalamus: 3.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 92.8;HDLM-2: 17.5;HSkMC: 31.4;SuSa: 16.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000355, HPA051194" Enhanced Uncertain Mitochondria NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Mitochondria "CAB000355: , HPA051194: AB_2681381" "unprognostic (9.41e-2)" "unprognostic (7.44e-2)" "unprognostic (9.52e-5)" "unprognostic (6.81e-2)" "unprognostic (2.72e-1)" "unprognostic (4.25e-4)" "unprognostic (5.18e-5)" "unprognostic (1.54e-3)" "unprognostic (2.38e-2)" "unprognostic (2.52e-1)" "unprognostic (1.97e-1)" "unprognostic (5.37e-2)" "unprognostic (1.54e-5)" "unprognostic (2.52e-3)" "unprognostic (2.11e-1)" "unprognostic (1.40e-2)" "unprognostic (1.11e-1)" 8.3 9.0 4.8 0.4 0.6 0.2 2.1 0.1 0.5 0.6 0.0 0.2 0.7 0.3 0.0 0.1 0.3 0.5 1.2 0.3 4.1 0.1 0.1 0.7 0.0 1.4 2.0 3.2 1.3 0.2 0.0 124.4 0.7 0.6 0.1 0.6 0.9 2.7 0.6 1.8 0.2 1.3 0.2 0.6 0.2 6.5 3.7 0.2 2.4 0.3 0.0 3.5 0.5 0.7 0.1 0.0 0.0 0.0 1.7 92.8 6.0 0.1 0.3 0.0 0.1 0.2 0.0 0.0 0.3 0.5 0.4 0.0 0.0 0.0 0.0 17.5 0.0 0.6 0.2 8.1 0.6 0.0 0.1 31.4 0.0 0.3 4.0 0.3 0.0 0.0 0.0 0.8 0.4 0.7 0.0 0.1 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 2.4 0.2 16.3 0.0 0.5 0.1 0.3 0.1 0.2 0.0 3.0 1.6 0.0 0.8 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.8 0.6 0.1 0.5 0.3 4.1 1.4 2.0 0.7 0.2 3.7 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 52.8 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.7 0.0 0.0 0.1 0.0 7.9 1.5 0.0 0.0 0.0 191.3 0.0 0.0 14.0 0.0 0.3 0.0 0.0 0.9 0.0 5.1 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.2 0.9 12.3 0.3 0.0 0.0 2007.5 0.0 22.2 0.0 0.0 CYP1B1 "CP1B, GLC3A" ENSG00000138061 "Cytochrome P450 family 1 subfamily B member 1" Q16678 2 38066973-38109902 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism, Steroid metabolism" "Lyase, Monooxygenase, Oxidoreductase" "Disease variant, Glaucoma, Peters anomaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Peritubular cells: 170.8;Prostatic glandular cells: 747.6;Urothelial cells: 498.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "classical monocyte: 156.9" "Lineage enriched" "Detected in many" 24 "monocytes: 156.9" "Cell line enhanced" "Detected in many" "ASC diff: 128.7;ASC TERT1: 136.8;HSkMC: 551.3;hTERT-RPE1: 128.9;SiHa: 270.0;U-87 MG: 142.2" "Low region specificity" "Detected in many" "Region enhanced" "Detected in all" "spinal cord: 34.6" "CAB011705, HPA026863" Approved Uncertain Mitochondria NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" Mitochondria "CAB011705: AB_731810, HPA026863: AB_10600900" "unprognostic (7.25e-3)" "unprognostic (2.28e-1)" "unprognostic (1.24e-3)" "unprognostic (2.27e-1)" "unprognostic (2.04e-2)" "unprognostic (1.68e-1)" "unprognostic (5.45e-2)" "unprognostic (1.80e-1)" "unprognostic (3.38e-1)" "unprognostic (9.69e-2)" "unprognostic (4.20e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (4.39e-6)" "unprognostic (1.87e-3)" "unprognostic (1.81e-1)" "unprognostic (6.67e-2)" "prognostic unfavorable (2.76e-4)" 28.4 12.0 2.7 31.9 6.2 2.0 29.4 1.6 8.9 34.9 10.4 3.7 2.2 41.0 19.5 7.6 44.9 23.8 29.2 2.5 2.3 24.1 7.0 16.8 11.6 3.6 2.9 5.6 7.2 0.9 14.8 4.5 3.0 34.7 2.1 1.2 4.3 39.2 3.4 6.3 5.8 35.1 3.6 27.3 15.9 8.0 7.3 28.3 8.7 5.5 1.9 35.0 6.7 1.5 7.0 71.9 2.3 0.0 128.7 136.8 0.4 0.6 4.4 1.3 12.3 0.2 30.1 0.0 19.1 17.8 3.1 58.7 0.3 4.0 2.3 5.5 3.8 0.0 21.2 0.0 36.0 0.2 0.1 551.3 55.3 30.7 1.4 128.9 0.0 0.3 0.7 0.2 0.7 29.2 0.3 22.5 7.5 10.4 14.2 0.1 0.0 0.2 13.4 0.9 0.5 2.1 270.0 38.8 0.0 7.5 49.4 10.8 0.0 1.1 0.2 107.9 0.1 0.3 0.2 0.0 142.2 0.1 11.8 1.6 156.9 0.0 0.1 23.2 0.0 0.1 0.1 0.0 1.5 0.0 0.1 0.1 6.5 0.1 18.6 0.7 0.1 70.2 2.7 6.2 1.6 8.9 2.5 2.3 3.6 2.9 3.0 3.6 7.3 1.5 56.8 19.2 66.3 0.0 1.7 17.7 118.4 86.9 8.0 0.7 18.3 42.0 3.4 0.0 79.7 46.0 0.0 0.3 1.1 0.9 15.6 6.0 15.1 11.7 100.4 103.8 1.8 0.0 4.5 0.5 0.8 114.1 3.6 28.2 3.8 0.1 7.5 12.2 12.6 0.0 0.3 1.3 4.1 103.0 50.6 12.1 159.7 112.2 17.8 64.6 140.1 1.6 3.1 0.0 0.2 0.6 0.1 170.8 0.3 747.6 0.1 1.6 11.2 0.5 19.7 4.5 32.7 12.6 2.6 2.4 14.2 0.3 2.4 1.3 1.0 498.7 D2HGDH "D2HGD, FLJ42195, MGC25181" ENSG00000180902 "D-2-hydroxyglutarate dehydrogenase" Q8N465 2 241734602-241768816 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.5" "Group enriched" "Detected in many" 4 "B-cells: 2.5;T-cells: 1.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056216, HPA060548" Uncertain Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA056216: AB_2683070, HPA060548: AB_2732650" "unprognostic (2.85e-1)" "unprognostic (3.35e-2)" "unprognostic (6.98e-3)" "unprognostic (7.88e-2)" "unprognostic (2.42e-1)" "prognostic favorable (9.11e-4)" "unprognostic (2.49e-3)" "unprognostic (1.67e-2)" "unprognostic (1.03e-1)" "unprognostic (1.65e-2)" "unprognostic (7.82e-3)" "unprognostic (1.21e-1)" "unprognostic (7.63e-2)" "unprognostic (1.48e-2)" "unprognostic (1.50e-1)" "unprognostic (9.60e-2)" "unprognostic (3.05e-2)" 11.5 17.7 6.9 11.2 8.0 18.6 7.6 6.2 7.3 10.5 14.9 16.6 11.4 11.8 13.0 15.0 16.1 14.1 11.4 6.6 6.1 15.9 19.1 10.6 12.0 8.4 6.9 14.8 16.6 15.2 10.5 8.9 6.6 14.6 14.6 3.2 18.7 14.9 33.8 39.4 14.9 9.3 6.1 15.1 14.7 4.9 7.3 7.4 18.0 23.7 11.5 8.9 9.6 8.6 10.2 10.5 6.2 9.6 14.7 7.9 21.5 9.7 12.2 9.6 7.7 11.8 21.9 8.3 4.4 9.7 11.0 23.2 5.9 7.8 4.0 8.8 5.7 15.9 11.3 20.5 8.2 19.0 12.1 14.1 13.7 7.6 7.3 18.5 9.5 13.1 20.7 5.3 8.6 16.8 16.0 19.7 3.0 13.8 20.8 19.5 6.9 16.2 17.6 36.7 20.4 7.2 9.4 23.8 6.6 4.1 14.7 6.7 4.1 14.9 5.6 7.9 5.8 9.9 1.9 13.4 10.3 20.8 10.0 0.0 0.2 0.0 0.2 0.2 0.4 2.5 0.1 1.0 0.4 0.1 0.6 0.2 0.0 0.0 0.3 0.1 0.8 0.1 6.9 8.0 6.2 7.3 6.6 6.1 8.4 6.9 6.6 6.1 7.3 8.6 10.4 9.6 14.3 33.3 10.4 19.8 23.5 13.7 25.6 14.3 22.8 22.7 10.6 25.8 16.3 18.4 14.6 44.0 13.0 40.9 23.5 10.5 3.6 12.5 13.2 9.7 31.8 6.9 7.1 8.7 15.9 15.7 23.0 19.2 5.7 28.0 13.2 46.0 18.2 11.8 9.9 56.4 14.2 10.8 7.5 4.8 16.8 12.6 3.6 15.9 5.3 37.4 8.2 28.6 12.8 6.7 32.0 18.0 15.0 19.3 26.4 31.4 13.9 12.0 6.6 14.0 11.7 2.1 7.0 25.7 14.8 22.6 14.0 27.0 49.9 22.2 DAND5 "CER2, CKTSF1B3, Coco, DANTE, DTE, FLJ38607, GREM3" ENSG00000179284 "DAN domain BMP antagonist family member 5" Q8N907 19 12965159-12974760 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "heart muscle: 8.5" "Cell type enriched" "Detected in some" 7 "Cardiomyocytes: 17.1" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "neutrophil: 1.5" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 16 "SH-SY5Y: 19.8" "Not detected" "Not detected" "HPA043493, HPA049472" Uncertain Approved Mitochondria "Secreted in other tissues" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA043493: AB_2732505, HPA049472: AB_2680781" "unprognostic (1.18e-2)" "unprognostic (4.63e-2)" "unprognostic (7.51e-2)" "unprognostic (4.63e-2)" "unprognostic (3.82e-2)" "unprognostic (8.71e-2)" "unprognostic (2.29e-2)" "unprognostic (3.18e-1)" "unprognostic (5.95e-3)" "unprognostic (7.27e-3)" "unprognostic (8.17e-2)" "unprognostic (2.15e-1)" "unprognostic (2.48e-10)" "unprognostic (4.43e-1)" "unprognostic (2.48e-2)" "unprognostic (6.77e-2)" "unprognostic (1.37e-1)" 0.1 0.9 0.4 0.1 0.4 0.7 0.3 0.9 0.4 0.1 1.6 2.0 0.2 0.1 0.2 0.1 0.1 0.3 8.5 0.4 0.3 0.1 0.0 0.1 0.1 0.5 0.2 0.1 0.2 0.8 0.1 0.0 0.7 0.1 0.3 0.7 0.4 0.0 0.1 0.3 0.3 0.3 0.2 0.0 0.3 0.3 0.5 0.1 0.2 0.2 0.0 0.1 0.0 0.8 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.2 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.1 0.4 0.0 0.8 0.3 0.0 0.0 0.2 0.2 0.0 0.3 0.0 0.2 0.0 0.7 0.4 1.2 0.0 0.4 0.3 0.1 0.2 0.0 0.1 0.2 0.0 0.1 0.1 0.0 1.0 19.8 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.2 0.2 0.0 0.2 0.4 0.0 0.1 0.0 0.2 0.1 1.2 0.1 0.4 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.3 0.2 0.4 1.5 0.4 0.1 0.4 0.0 0.1 0.4 0.4 0.9 0.4 0.4 0.3 0.5 0.2 0.7 0.2 0.5 0.8 0.5 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.7 1.3 17.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.1 0.4 0.5 0.0 0.0 0.1 0.4 0.1 0.4 0.0 0.3 0.0 2.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.3 0.3 0.3 0.6 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.2 0.1 0.0 0.6 0.0 2.1 0.5 0.1 0.2 0.3 0.3 0.0 0.1 0.1 0.5 0.1 DBT "BCKAD-E2, BCKDH-E2, BCOADC-E2" ENSG00000137992 "Dihydrolipoamide branched chain transacylase E2" P11182 1 100186919-100249834 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Acyltransferase, Transferase" "Disease variant, Maple syrup urine disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 65.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026481, HPA026485, HPA026533" Enhanced Supported Mitochondria NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA026481: AB_1847504, HPA026485: AB_1847505, HPA026533: AB_1847506" "unprognostic (1.23e-1)" "unprognostic (1.23e-1)" "unprognostic (3.67e-2)" "unprognostic (5.29e-2)" "unprognostic (1.92e-2)" "unprognostic (1.63e-1)" "unprognostic (3.88e-2)" "unprognostic (1.65e-2)" "unprognostic (6.01e-2)" "unprognostic (1.21e-1)" "unprognostic (2.37e-2)" "unprognostic (2.90e-1)" "prognostic favorable (8.79e-12)" "unprognostic (1.63e-1)" "unprognostic (3.77e-1)" "unprognostic (9.67e-2)" "unprognostic (9.92e-2)" 11.1 13.6 4.4 5.9 5.2 4.6 11.8 4.3 4.9 11.3 3.7 9.2 8.0 8.2 6.0 12.8 11.1 6.3 25.9 4.2 5.0 30.3 43.4 7.4 7.5 5.6 4.6 11.1 15.4 19.4 2.3 10.0 4.5 15.9 10.2 5.9 12.8 11.2 13.4 7.4 7.1 8.0 4.6 6.1 17.3 4.7 5.2 9.9 17.2 19.2 8.9 9.4 4.0 7.1 18.5 8.2 9.5 17.4 23.9 17.6 20.6 13.1 12.3 13.9 15.6 17.7 7.4 17.1 18.3 9.3 8.1 18.7 20.3 17.7 16.8 18.2 11.5 12.1 16.3 9.5 18.0 16.1 6.1 18.2 18.1 10.6 17.9 11.4 12.4 17.9 20.9 19.2 11.1 4.9 14.4 4.1 18.6 14.8 18.4 14.1 30.3 14.2 15.3 15.9 15.8 8.7 27.5 25.4 23.7 16.7 20.9 11.9 10.8 12.1 7.6 15.9 11.0 12.7 14.1 9.1 13.8 10.7 5.3 2.1 1.2 0.8 2.2 1.5 2.4 1.9 2.0 1.9 1.2 2.1 1.8 1.9 1.1 2.0 1.4 1.3 1.5 1.1 4.4 5.2 4.3 4.9 4.2 5.0 5.6 4.6 4.5 4.6 5.2 7.1 9.6 22.4 36.4 29.0 9.6 6.8 6.5 9.8 13.6 22.2 11.9 8.5 65.9 18.6 11.3 12.9 39.6 19.8 10.9 11.4 50.9 10.0 0.8 18.5 20.5 11.7 9.1 8.2 24.0 8.5 11.6 11.3 15.8 15.4 2.5 19.6 15.4 53.2 8.7 15.2 25.2 12.0 14.2 8.8 5.0 1.7 15.2 7.3 3.6 3.7 10.3 14.5 12.3 22.1 26.1 6.4 6.0 21.1 7.1 9.4 9.9 32.1 18.0 22.4 6.6 15.0 12.9 2.8 6.1 18.7 7.2 8.2 9.7 17.3 15.1 5.5 DCAF5 "BCRG2, BCRP2, D14S1461E, KIAA1824, WDR22" ENSG00000139990 "DDB1 and CUL4 associated factor 5" Q96JK2 14 69050881-69153150 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 149.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041575, HPA048098" Uncertain Approved Mitochondria NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 34: Spermatids - Unknown function" Mitochondria "HPA041575: AB_2677558, HPA048098: AB_2680263" "unprognostic (8.12e-2)" "unprognostic (3.28e-2)" "unprognostic (4.26e-3)" "unprognostic (3.30e-1)" "unprognostic (1.58e-1)" "unprognostic (3.44e-1)" "unprognostic (2.27e-2)" "unprognostic (3.13e-2)" "unprognostic (1.25e-1)" "unprognostic (2.43e-1)" "unprognostic (5.80e-2)" "unprognostic (1.02e-1)" "unprognostic (1.63e-2)" "unprognostic (2.80e-2)" "unprognostic (1.02e-1)" "unprognostic (1.30e-1)" "unprognostic (2.06e-1)" 30.0 22.5 16.1 23.4 15.9 30.2 27.2 16.4 16.5 29.3 17.0 34.0 21.6 28.3 22.3 30.9 28.8 24.4 31.3 16.5 16.6 24.6 31.4 31.0 27.6 15.8 15.0 28.5 22.0 36.4 28.8 25.4 16.0 29.8 21.2 20.8 27.2 25.1 74.3 30.5 25.9 32.7 14.1 27.7 26.2 60.5 17.2 39.4 30.1 51.7 25.6 29.2 28.3 14.5 48.3 15.0 34.7 32.5 37.7 32.9 22.7 22.2 32.1 24.9 31.2 19.4 29.9 26.4 19.9 34.7 18.8 23.0 24.7 33.2 23.2 36.0 13.7 28.4 15.8 14.0 28.6 10.9 33.2 37.3 34.0 22.3 31.1 43.0 37.7 31.1 22.4 21.6 25.1 28.6 34.7 19.0 15.6 22.6 23.7 22.8 32.9 10.6 33.1 37.0 24.7 27.8 29.7 30.7 19.4 29.7 37.5 22.0 34.4 42.2 39.4 19.6 13.2 28.4 9.9 23.9 28.1 13.0 13.0 21.1 4.3 16.4 31.0 4.0 26.3 8.2 16.7 23.0 5.7 8.6 15.7 19.7 5.4 32.3 3.0 6.0 8.2 13.1 16.1 15.9 16.4 16.5 16.5 16.6 15.8 15.0 16.0 14.1 17.2 14.5 28.8 44.8 57.8 71.8 24.9 26.3 19.1 21.4 38.1 18.5 23.3 19.0 58.8 32.9 39.4 14.7 27.1 19.4 43.6 20.9 1.9 25.1 149.9 28.7 30.6 32.1 23.4 25.6 88.8 24.9 19.3 27.2 32.1 31.9 37.2 28.0 26.0 33.2 19.6 18.5 85.6 22.0 22.4 19.7 23.7 89.3 31.1 24.3 10.6 74.9 21.8 22.3 52.5 76.9 61.6 29.2 16.0 34.3 35.8 19.9 20.9 14.0 41.2 24.9 46.0 29.1 26.6 75.2 19.8 37.9 19.9 15.3 38.0 31.2 21.3 23.5 DDAH2 G6A ENSG00000213722 "Dimethylarginine dimethylaminohydrolase 2" O95865 6 31727038-31730617 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 386.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 63.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012389, HPA012509" Uncertain Supported Mitochondria NA NA 1500000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA012389: , HPA012509: AB_1847533" "unprognostic (2.29e-2)" "unprognostic (1.38e-1)" "unprognostic (4.49e-2)" "unprognostic (2.39e-1)" "unprognostic (1.44e-1)" "unprognostic (7.67e-2)" "unprognostic (1.50e-2)" "unprognostic (1.10e-1)" "unprognostic (2.62e-1)" "unprognostic (8.78e-2)" "unprognostic (1.01e-1)" "unprognostic (1.09e-1)" "unprognostic (1.02e-1)" "unprognostic (9.42e-2)" "unprognostic (2.32e-1)" "unprognostic (2.24e-2)" "unprognostic (2.72e-2)" 96.5 17.2 26.6 12.0 24.7 10.8 81.2 24.2 44.7 131.5 26.1 72.2 4.4 94.4 8.7 39.0 80.5 44.0 63.2 23.9 33.5 67.1 32.1 62.3 20.6 31.8 28.2 67.7 16.5 17.5 26.0 18.3 28.1 65.2 7.7 5.8 58.2 27.0 13.4 67.7 38.9 11.9 32.0 49.4 35.4 13.4 27.4 9.6 65.1 4.5 7.8 61.0 91.0 30.9 2.0 20.1 0.7 28.5 17.0 26.6 3.8 0.0 10.6 10.9 7.3 40.4 6.7 0.4 24.4 26.5 0.9 2.4 0.5 9.7 1.9 0.0 14.2 1.9 7.8 22.4 18.2 0.3 1.5 18.8 1.2 12.2 0.9 3.7 33.3 14.1 0.4 11.1 4.8 63.0 1.5 27.5 4.1 4.3 12.2 0.2 0.9 10.5 21.6 0.5 1.5 5.7 0.0 4.7 27.4 2.9 37.7 7.8 0.1 16.9 24.7 11.2 0.0 4.1 12.8 3.3 11.3 5.9 4.3 141.3 15.4 135.0 14.8 37.4 5.8 49.7 4.0 5.3 26.8 39.6 2.7 3.4 27.8 29.2 44.9 93.9 4.1 11.4 26.6 24.7 24.2 44.7 23.9 33.5 31.8 28.2 28.1 32.0 27.4 30.9 102.3 28.9 14.7 10.4 76.8 66.9 88.7 49.6 56.3 4.5 132.8 96.0 39.5 62.9 36.9 82.8 29.2 15.5 84.4 386.3 178.1 148.2 83.1 62.6 94.2 101.2 150.0 20.4 0.3 32.3 37.3 154.1 33.1 75.0 113.3 121.7 94.9 31.9 223.2 0.0 0.3 71.5 109.9 139.7 301.2 23.6 180.5 95.7 103.2 14.0 64.2 120.9 40.2 4.5 2.7 85.1 299.5 153.1 24.5 95.2 61.5 165.8 50.5 25.7 105.2 122.7 153.0 4.1 12.5 35.8 59.2 18.1 41.1 21.3 104.6 67.0 DDT "D-DT, DDCT, MIF-2, MIF2" ENSG00000099977 "D-dopachrome tautomerase" P30046 22 23971365-23979828 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Melanin biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 835.9" "Cell type enhanced" "Detected in all" "Hepatocytes: 4869.6;Proximal tubular cells: 1415.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEK 293: 262.9" "HPA049871, HPA074115" Approved Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 2: Hepatocytes - Metabolism" Mitochondria "HPA049871: AB_2680926, HPA074115: " "unprognostic (1.77e-2)" "unprognostic (1.13e-1)" "unprognostic (1.40e-1)" "unprognostic (1.22e-2)" "unprognostic (8.09e-2)" "unprognostic (4.00e-3)" "unprognostic (2.02e-3)" "unprognostic (6.58e-2)" "unprognostic (4.66e-2)" "unprognostic (2.23e-2)" "unprognostic (1.96e-1)" "unprognostic (6.06e-3)" "unprognostic (1.12e-1)" "unprognostic (7.34e-2)" "unprognostic (3.30e-1)" "unprognostic (3.81e-1)" "unprognostic (2.61e-3)" 125.7 126.7 29.6 15.1 30.6 39.6 99.0 33.1 38.0 69.6 28.7 128.5 44.2 62.6 16.2 119.1 67.3 6.3 167.0 28.9 32.2 218.2 835.9 69.2 13.7 30.7 29.6 83.0 260.9 24.3 47.7 10.7 30.7 109.0 24.2 12.8 82.7 15.7 129.3 89.8 120.7 8.6 30.7 66.3 176.2 39.2 32.9 12.3 80.1 15.7 11.9 86.8 76.4 33.9 107.6 44.8 15.4 34.9 29.0 24.9 92.6 30.4 20.7 26.1 27.1 39.8 30.6 101.9 27.8 16.1 37.7 86.3 38.3 38.1 17.1 43.6 262.9 60.8 58.9 88.3 28.9 136.2 58.8 25.5 28.5 26.3 23.1 27.9 28.7 16.0 56.8 40.2 26.9 53.0 30.1 123.1 46.2 94.4 134.2 65.3 27.0 148.9 46.4 39.2 51.7 49.2 62.8 117.7 95.9 20.6 30.8 42.3 33.1 26.8 59.9 27.8 32.2 122.6 43.9 65.1 53.1 49.7 52.5 63.5 92.9 72.4 46.0 82.8 47.5 75.3 55.3 49.1 87.8 70.7 49.2 48.9 58.3 61.6 79.1 130.4 74.5 78.8 29.6 30.6 33.1 38.0 28.9 32.2 30.7 29.6 30.7 30.7 32.9 33.9 116.9 83.3 86.3 11.1 178.3 138.9 220.5 278.8 176.4 58.4 266.6 379.7 21.3 499.0 153.2 242.8 89.6 202.6 134.1 533.1 718.1 237.2 202.1 150.8 126.4 103.4 259.6 230.2 9.1 375.7 288.2 103.9 163.1 260.3 129.4 97.1 154.9 4869.6 281.0 43.7 11.0 402.8 187.2 240.4 162.2 411.0 117.1 172.2 158.3 9.4 235.8 119.6 135.9 6.0 18.8 233.6 395.1 110.6 166.1 257.5 935.1 1415.8 97.6 100.0 78.9 109.5 127.6 117.9 43.8 280.6 188.0 299.8 140.3 212.5 558.7 291.3 DDX49 "Dbp8, FLJ10432" ENSG00000105671 "DEAD-box helicase 49" Q9Y6V7 19 18919705-18929189 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 103.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041870, HPA048093" Enhanced Approved Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA041870: AB_2677717, HPA048093: AB_2680262" "unprognostic (3.51e-1)" "prognostic favorable (2.01e-6)" "unprognostic (2.28e-2)" "unprognostic (1.28e-1)" "unprognostic (8.56e-2)" "unprognostic (1.60e-2)" "prognostic unfavorable (7.05e-4)" "unprognostic (4.12e-2)" "unprognostic (2.41e-3)" "unprognostic (8.67e-2)" "unprognostic (6.46e-3)" "unprognostic (5.13e-2)" "prognostic unfavorable (7.44e-5)" "unprognostic (3.93e-2)" "unprognostic (2.99e-2)" "unprognostic (4.97e-2)" "unprognostic (3.24e-1)" 16.5 17.7 17.1 13.9 17.3 23.3 15.5 17.9 22.1 16.0 14.0 17.4 15.7 15.9 5.9 25.9 13.9 7.9 18.2 18.2 16.5 15.6 24.9 13.7 16.1 17.1 16.0 14.6 20.1 12.6 11.3 13.4 16.7 16.4 7.4 4.8 18.0 10.8 33.6 27.1 14.8 9.9 17.7 16.1 15.7 19.2 17.3 14.1 13.6 13.6 10.3 17.5 17.5 19.3 46.5 47.4 19.0 61.3 28.1 21.1 71.0 29.2 19.8 50.9 40.1 54.6 45.8 60.6 86.7 29.1 16.1 39.4 42.9 39.8 14.8 18.9 110.5 29.9 49.9 48.6 63.5 77.5 40.1 44.4 35.9 40.7 41.9 14.4 23.3 46.9 58.2 43.1 18.2 104.4 56.6 37.9 62.7 50.3 112.8 62.8 31.5 65.9 27.4 28.2 67.2 69.7 38.2 36.6 48.2 9.8 39.2 37.6 29.5 24.3 27.9 92.0 48.7 55.5 73.0 57.1 31.1 88.8 39.3 17.1 21.9 16.7 14.8 26.2 12.0 9.1 11.0 11.1 31.1 9.8 10.9 12.1 8.6 19.5 18.1 13.7 18.0 12.7 17.1 17.3 17.9 22.1 18.2 16.5 17.1 16.0 16.7 17.7 17.3 19.3 15.6 3.2 10.0 4.9 20.5 22.6 18.7 28.0 14.8 19.5 25.2 29.1 13.8 27.1 20.5 18.4 4.2 46.5 27.0 48.0 37.2 35.0 37.2 18.8 26.5 15.3 25.8 18.3 7.4 52.2 50.3 19.0 19.4 24.7 18.4 25.1 7.5 14.8 33.5 10.1 7.6 31.5 30.5 21.0 22.0 103.0 21.5 18.8 26.6 4.7 28.5 18.3 29.9 6.0 8.2 29.8 30.7 19.9 29.5 21.5 48.0 25.0 12.5 24.1 19.7 21.1 26.9 33.4 31.8 29.5 28.3 42.1 20.8 38.1 39.4 21.5 DEGS1 "DEGS-1, Des-1, DES1, FADS7, MLD" ENSG00000143753 "Delta 4-desaturase, sphingolipid 1" O15121 1 224175756-224193441 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "skin 1: 535.6" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 246.0;Cytotrophoblasts: 281.8;Suprabasal keratinocytes: 320.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076422 Supported Mitochondria NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 61: Skin - Cornification" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA076422: AB_2686799" "unprognostic (2.34e-2)" "unprognostic (6.91e-2)" "unprognostic (2.48e-2)" "prognostic unfavorable (7.74e-5)" "unprognostic (1.50e-1)" "unprognostic (2.74e-1)" "prognostic unfavorable (4.29e-5)" "unprognostic (7.70e-2)" "unprognostic (2.31e-1)" "unprognostic (3.20e-1)" "unprognostic (3.63e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (6.83e-7)" "unprognostic (2.87e-1)" "unprognostic (1.61e-1)" "unprognostic (3.86e-2)" "prognostic unfavorable (2.53e-4)" 60.3 31.0 30.3 44.9 33.1 69.5 61.9 35.0 36.2 53.4 42.5 50.8 47.0 44.5 29.5 48.6 34.4 40.5 43.8 31.3 35.6 38.1 35.7 49.1 48.0 36.6 35.2 27.1 22.5 31.5 34.8 128.7 35.9 83.2 27.2 20.8 38.7 58.6 20.9 535.6 33.4 70.9 37.9 38.7 38.6 22.7 34.0 34.2 52.3 23.3 50.9 48.4 72.7 44.5 72.8 50.7 65.2 49.5 275.7 181.1 51.2 201.1 223.8 137.5 164.2 47.1 55.2 58.0 252.4 181.0 82.4 76.3 76.5 67.9 153.0 84.2 141.5 41.7 51.1 29.2 167.9 84.2 86.1 177.4 153.6 125.5 69.9 143.0 140.4 31.4 62.8 61.8 181.2 27.5 43.2 46.9 83.3 40.0 76.1 38.8 92.4 37.5 181.1 19.8 42.3 69.8 106.6 169.4 110.4 118.8 57.1 123.4 125.7 133.4 41.4 153.1 197.5 44.5 55.3 52.8 141.9 41.7 154.2 104.6 61.4 120.3 30.9 67.8 59.8 58.2 52.7 43.3 104.4 74.3 40.7 37.0 67.7 43.9 48.7 34.9 59.0 52.8 30.3 33.1 35.0 36.2 31.3 35.6 36.6 35.2 35.9 37.9 34.0 44.5 71.7 83.3 29.3 13.4 69.9 246.0 44.0 33.6 89.4 31.2 40.7 38.4 20.8 10.0 19.8 11.0 14.6 281.8 40.5 4.0 13.7 34.9 27.9 54.0 90.2 66.7 14.9 18.7 17.4 43.3 48.3 77.7 21.4 146.1 106.5 21.3 55.6 20.8 93.0 18.5 20.4 6.2 34.6 57.8 90.5 13.6 63.0 72.8 69.4 20.6 57.1 26.0 10.3 25.6 32.1 29.5 5.9 79.4 50.1 44.2 20.1 29.7 20.1 18.4 105.2 42.7 89.1 84.3 44.0 50.4 320.4 198.9 58.9 43.7 6.6 13.7 DHFR ENSG00000228716 "Dihydrofolate reductase" P00374 5 80626226-80654983 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Methotrexate resistance, One-carbon metabolism" "Oxidoreductase, RNA-binding" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 145.8;Spermatocytes: 132.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037129, HPA051465" Uncertain Approved Mitochondria NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Mitochondria "CAB037129: AB_439683, HPA051465: AB_2681494" "unprognostic (1.44e-2)" "unprognostic (1.03e-2)" "unprognostic (2.24e-3)" "unprognostic (2.91e-3)" "unprognostic (3.27e-1)" "unprognostic (1.32e-1)" "unprognostic (2.83e-2)" "unprognostic (2.35e-2)" "unprognostic (2.02e-2)" "unprognostic (4.19e-3)" "unprognostic (1.83e-2)" "unprognostic (2.55e-1)" "unprognostic (1.15e-2)" "unprognostic (1.82e-2)" "unprognostic (2.49e-1)" "unprognostic (1.57e-1)" "unprognostic (1.09e-1)" 25.2 5.3 15.3 20.7 16.5 54.3 12.0 15.8 21.9 8.0 13.3 21.4 24.5 8.6 7.0 14.1 7.4 8.5 7.2 13.8 15.5 21.3 60.1 7.5 41.5 16.6 16.6 6.6 3.2 9.1 6.3 14.4 16.6 8.9 25.3 10.3 6.8 9.5 19.6 9.8 25.1 12.0 16.5 10.3 12.2 18.5 15.8 60.7 8.2 25.8 39.5 10.3 5.7 17.7 98.1 66.6 164.8 122.7 30.7 32.0 60.6 76.5 58.1 130.2 149.0 63.8 114.6 196.9 32.5 44.6 106.0 67.0 214.4 98.6 208.5 88.2 132.1 94.8 104.5 59.5 6.6 111.7 40.3 22.3 9.9 116.9 13.0 22.2 63.9 142.0 108.3 146.7 133.5 98.2 276.5 44.9 83.6 48.3 38.5 176.7 323.3 194.1 75.1 61.5 134.3 93.7 107.9 49.9 54.6 83.5 98.5 108.6 38.5 41.0 62.0 116.0 148.3 68.2 146.6 210.3 91.5 222.1 107.7 0.2 0.3 0.2 0.5 0.6 0.2 0.5 0.6 0.8 0.5 0.5 0.5 0.6 0.8 0.5 0.5 0.8 0.9 0.6 15.3 16.5 15.8 21.9 13.8 15.5 16.6 16.6 16.6 16.5 15.8 17.7 4.1 6.4 11.7 4.9 21.4 6.9 6.5 6.0 4.0 3.5 8.9 8.9 13.0 4.3 6.1 14.7 2.1 35.2 7.4 19.3 9.8 7.4 7.4 10.8 7.7 7.7 4.9 145.8 7.3 3.7 47.3 12.0 11.7 8.0 2.5 22.0 10.0 48.3 44.7 3.3 7.2 19.1 4.1 18.9 4.4 6.4 14.0 12.8 0.0 4.7 7.1 14.5 13.4 3.5 6.0 4.7 10.3 16.1 60.9 2.9 26.6 40.0 6.9 3.2 13.1 9.0 12.5 132.2 49.8 21.2 5.5 13.3 11.8 12.3 38.1 12.1 DHFR2 "DHFRL1, DHFRP4, FLJ16119" ENSG00000178700 "Dihydrofolate reductase 2" Q86XF0 3 94047836-94063389 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "One-carbon metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 12.8;Ductal cells: 6.3;Respiratory ciliated cells: 8.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 13 "hTERT-RPE1: 154.6" HPA051465 Uncertain Approved Mitochondria NA NA "Cluster 32: T-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA051465: AB_2681494" "unprognostic (1.16e-1)" "unprognostic (1.15e-1)" "unprognostic (1.10e-2)" "unprognostic (3.50e-2)" "unprognostic (2.07e-1)" "unprognostic (1.38e-1)" "unprognostic (5.92e-2)" "unprognostic (1.33e-1)" "unprognostic (1.12e-1)" "unprognostic (4.62e-2)" "unprognostic (2.95e-1)" "unprognostic (1.52e-1)" "prognostic favorable (2.30e-6)" "unprognostic (1.63e-1)" "unprognostic (1.79e-1)" "unprognostic (1.13e-1)" "unprognostic (2.96e-2)" 3.3 4.9 3.9 3.8 5.2 1.8 5.3 6.0 5.2 5.2 4.8 4.2 4.1 7.9 6.4 3.5 6.3 5.1 3.7 4.1 4.1 5.9 6.7 4.5 5.7 4.8 4.2 10.1 5.3 6.5 2.5 3.2 5.0 6.4 4.6 3.2 4.4 4.9 1.4 4.2 4.9 5.4 4.2 4.9 4.7 4.7 4.4 5.7 6.7 2.1 4.6 3.3 2.4 6.5 3.8 6.5 4.2 4.4 5.7 7.2 1.7 5.7 6.0 2.8 3.2 1.4 5.7 2.5 3.8 3.0 3.7 5.0 3.3 3.9 4.4 8.5 1.8 3.1 2.9 3.4 6.0 2.2 3.6 7.6 5.1 3.3 4.2 154.6 2.9 11.9 1.6 5.6 3.7 4.5 10.8 1.2 3.7 10.8 6.7 2.7 5.7 4.1 4.1 1.9 5.4 5.3 8.3 2.2 9.6 3.3 5.6 3.1 4.8 4.4 7.4 1.8 2.2 4.1 4.4 3.5 4.4 5.5 6.2 2.2 1.1 2.0 1.8 1.7 3.3 1.8 2.4 2.9 0.7 2.2 3.2 3.0 1.7 1.4 1.8 2.1 3.2 1.3 3.9 5.2 6.0 5.2 4.1 4.1 4.8 4.2 5.0 4.2 4.4 6.5 2.8 12.8 5.8 0.0 0.9 0.0 0.0 0.0 0.0 0.0 3.6 3.4 0.0 0.0 1.8 3.7 0.0 2.4 2.3 0.0 3.9 6.3 0.0 3.5 4.4 2.5 0.0 0.0 0.0 5.5 1.7 2.5 0.0 2.9 2.5 4.9 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 2.6 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.4 0.0 0.0 5.6 8.7 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.8 1.3 3.5 0.0 0.0 DHTKD1 "CMT2Q, DKFZP762M115, KIAA1630, MGC3090" ENSG00000181192 "Dehydrogenase E1 and transketolase domain containing 1" Q96HY7 10 12068954-12123221 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis Oxidoreductase "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 129.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 227.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "T-47d: 102.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037949, HPA037950, HPA066098" Enhanced Supported Mitochondria NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA037949: AB_2675752, HPA037950: AB_10673650, HPA066098: AB_2685617" "unprognostic (3.76e-2)" "unprognostic (8.08e-3)" "unprognostic (2.24e-1)" "unprognostic (1.15e-1)" "unprognostic (1.34e-1)" "unprognostic (3.04e-3)" "unprognostic (3.83e-3)" "unprognostic (5.01e-2)" "unprognostic (5.34e-2)" "unprognostic (3.02e-3)" "unprognostic (3.46e-1)" "unprognostic (1.56e-1)" "prognostic favorable (3.43e-4)" "unprognostic (2.12e-1)" "unprognostic (1.31e-1)" "unprognostic (1.74e-2)" "unprognostic (2.88e-3)" 10.7 8.4 8.1 6.8 10.4 3.8 8.4 12.6 8.5 8.8 11.9 10.1 7.6 6.2 6.8 7.5 6.1 5.3 13.2 7.6 8.5 42.7 129.5 5.4 8.5 9.5 8.6 10.0 18.0 12.7 5.6 7.7 9.5 12.9 10.8 7.5 13.1 5.7 18.7 5.6 6.9 5.7 8.8 7.8 10.9 4.7 9.1 10.5 11.6 23.1 9.7 6.3 6.1 11.4 27.0 20.4 29.8 23.8 18.2 10.8 35.9 13.3 8.6 23.4 20.6 13.1 15.7 19.3 4.3 8.4 10.8 37.4 31.6 10.4 26.6 10.9 14.2 10.6 7.7 10.1 17.8 4.2 3.8 13.3 7.9 13.7 5.5 9.2 13.0 23.1 16.7 15.1 6.3 52.3 14.4 7.7 16.7 24.9 4.7 24.3 9.7 16.5 15.2 6.4 7.7 34.9 26.3 46.3 15.4 31.7 102.2 15.2 5.8 7.5 5.4 15.8 9.9 13.4 10.3 12.6 9.7 7.4 12.8 23.8 6.8 15.4 4.2 9.2 4.5 13.0 3.2 2.7 11.9 9.9 3.1 4.1 19.4 14.3 17.0 17.3 5.7 4.9 8.1 10.4 12.6 8.5 7.6 8.5 9.5 8.6 9.5 8.8 9.1 11.4 6.9 12.8 38.8 21.5 21.3 5.2 6.7 5.3 10.2 13.3 13.7 8.3 31.1 28.6 7.8 16.5 10.4 35.4 23.2 14.6 19.6 10.9 3.5 8.8 17.3 8.1 11.3 21.9 12.8 11.1 25.1 8.1 21.9 20.8 8.8 45.2 11.0 227.4 10.3 26.9 17.3 18.0 4.1 15.3 10.1 4.2 12.5 13.5 5.4 17.8 13.4 10.4 8.2 15.6 20.5 12.4 9.6 12.0 22.6 9.6 9.4 62.5 5.2 19.2 13.1 10.6 7.4 6.7 3.8 16.2 6.0 13.5 8.4 21.8 16.6 7.8 DIABLO "DFNA64, DIABLO-S, FLJ10537, FLJ25049, SMAC" ENSG00000184047 "Diablo IAP-binding mitochondrial protein" Q9NR28 12 122207663-122227456 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 31.3;Plasma cells: 29.2;Squamous epithelial cells: 30.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001825, CAB003857, CAB016688" Supported Enhanced Mitochondria NA Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 43: Testis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Mitochondria "CAB003857: AB_365498, CAB016688: AB_1615783, HPA001825: AB_1857247" "unprognostic (3.67e-2)" "unprognostic (1.90e-1)" "unprognostic (1.11e-1)" "unprognostic (3.10e-3)" "unprognostic (1.64e-1)" "unprognostic (2.38e-3)" "unprognostic (1.40e-3)" "unprognostic (5.06e-2)" "unprognostic (1.48e-1)" "unprognostic (1.03e-1)" "unprognostic (1.33e-2)" "unprognostic (4.05e-2)" "prognostic unfavorable (5.35e-4)" "unprognostic (6.68e-2)" "unprognostic (2.36e-1)" "unprognostic (2.00e-1)" "unprognostic (1.40e-1)" 23.8 34.3 29.8 17.3 30.8 32.5 25.3 33.7 36.8 21.4 30.4 28.7 21.7 27.0 36.1 30.8 23.3 18.0 30.3 28.7 32.0 34.5 39.6 21.2 21.0 32.0 31.4 27.8 27.7 32.2 41.4 25.8 32.1 21.9 24.5 27.5 28.9 19.5 37.4 25.4 26.9 20.5 33.6 24.3 26.6 53.2 31.0 26.9 25.8 34.5 24.9 32.0 24.5 33.4 49.0 94.7 65.4 44.7 45.9 44.6 50.2 49.5 48.3 56.9 50.8 82.4 24.9 59.2 45.4 45.2 42.4 47.4 72.2 59.3 67.0 51.1 56.4 65.2 36.6 76.7 65.3 71.0 25.9 62.2 41.3 67.3 100.1 64.4 66.8 57.9 75.9 24.5 56.1 72.4 58.6 103.8 52.9 69.5 88.0 52.3 65.2 65.4 64.4 74.7 61.7 62.6 66.1 26.2 54.8 73.3 87.9 49.2 46.0 43.7 53.6 50.0 45.4 52.8 95.5 84.3 55.8 53.6 58.8 43.3 39.8 39.8 39.9 41.4 37.8 46.3 36.4 37.2 48.3 36.4 35.6 36.1 17.9 45.5 40.1 37.5 46.3 42.0 29.8 30.8 33.7 36.8 28.7 32.0 32.0 31.4 32.1 33.6 31.0 33.4 0.2 0.0 0.6 7.2 19.7 5.0 5.9 7.6 31.3 7.3 0.0 0.0 1.3 10.0 3.3 0.0 4.2 11.3 3.0 8.2 0.0 0.2 6.3 0.0 0.0 3.8 7.3 20.4 14.5 0.0 10.8 7.7 25.5 0.0 4.5 0.0 5.3 2.9 6.5 3.3 14.1 8.8 8.2 3.3 3.6 4.6 5.6 7.1 3.6 3.7 2.7 7.6 9.2 9.0 15.1 0.2 11.9 3.4 29.2 3.9 16.8 0.1 1.7 11.1 6.6 2.6 4.9 19.2 16.3 30.4 4.8 13.4 13.2 0.0 9.9 3.9 DLAT "DLTA, E2, PDC-E2" ENSG00000150768 "Dihydrolipoamide S-acetyltransferase" P10515 11 112025408-112064404 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism, Tricarboxylic acid cycle" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 89.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 100.5;Distal tubular cells: 74.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003782, HPA040786, HPA062766" Supported Supported Mitochondria NA NA 44000 "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB003782: , HPA040786: AB_2677136, HPA062766: AB_2684864" "unprognostic (4.57e-3)" "unprognostic (1.75e-1)" "prognostic favorable (6.19e-6)" "unprognostic (7.68e-2)" "unprognostic (2.41e-1)" "unprognostic (1.70e-2)" "prognostic unfavorable (7.49e-5)" "unprognostic (8.68e-2)" "unprognostic (5.36e-2)" "unprognostic (2.93e-1)" "unprognostic (2.23e-3)" "unprognostic (6.25e-2)" "prognostic favorable (1.95e-14)" "unprognostic (5.82e-2)" "unprognostic (4.12e-2)" "unprognostic (2.17e-1)" "unprognostic (6.15e-2)" 24.7 16.5 7.7 13.3 8.3 7.9 14.5 9.5 9.3 11.0 10.4 24.7 18.3 10.0 13.4 19.5 13.0 8.5 69.4 8.1 11.1 33.8 15.5 11.7 16.1 8.3 8.9 9.5 6.8 31.7 8.5 13.1 9.7 14.5 26.0 10.8 16.8 14.8 75.4 10.3 16.5 13.4 8.2 9.9 14.3 9.9 9.4 12.7 20.2 89.4 18.2 14.2 8.1 8.0 18.7 16.4 28.2 34.4 41.6 30.5 26.5 26.6 18.2 34.8 38.7 52.8 56.7 85.4 46.0 28.7 42.6 41.0 65.7 34.2 38.9 27.3 30.2 51.9 17.9 39.2 29.0 64.9 26.6 36.9 37.7 32.0 35.2 24.2 33.9 41.7 88.4 42.6 41.2 16.6 25.4 66.9 30.3 58.6 35.4 45.4 38.0 93.3 64.4 21.4 51.2 27.8 30.7 93.4 20.5 30.9 67.4 42.9 17.8 29.1 29.1 29.1 33.0 11.1 19.4 127.5 7.7 73.0 22.7 9.1 3.8 3.0 4.3 5.8 5.4 5.6 4.9 5.1 5.8 4.0 5.6 5.1 0.3 4.7 6.1 4.5 5.8 5.0 7.7 8.3 9.5 9.3 8.1 11.1 8.3 8.9 9.7 8.2 9.4 8.0 7.6 12.8 14.5 15.3 13.8 11.2 9.2 18.2 14.2 8.1 9.2 5.8 100.5 15.7 13.2 11.0 0.0 21.2 6.4 26.3 74.3 18.7 3.9 15.8 11.6 9.6 17.3 18.1 18.0 11.4 39.6 11.7 11.7 12.1 3.8 13.5 7.5 15.5 18.7 8.4 24.4 17.8 24.4 8.8 7.5 3.2 6.2 9.5 17.8 9.4 16.7 10.4 4.1 11.1 19.7 14.1 9.2 10.9 19.4 7.0 19.0 37.6 30.3 11.1 0.0 14.2 19.9 25.1 18.3 21.1 9.8 17.4 8.5 26.3 26.7 9.3 DMAC2 "ATP5SL, FLJ10241" ENSG00000105341 "Distal membrane arm assembly complex 2" Q9NW81 19 41431318-41440717 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 47.9;Distal tubular cells: 39.2;Ductal cells: 44.0;Exocrine glandular cells: 40.5;Extravillous trophoblasts: 67.9;Hofbauer cells: 40.4;Proximal tubular cells: 46.3;Syncytiotrophoblasts: 46.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041427 Approved Approved Mitochondria NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA041427: AB_2677473" "unprognostic (1.42e-3)" "unprognostic (1.12e-1)" "unprognostic (3.17e-2)" "unprognostic (1.20e-1)" "unprognostic (6.88e-3)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.77e-4)" "unprognostic (4.37e-1)" "unprognostic (3.83e-2)" "unprognostic (1.18e-2)" "unprognostic (1.52e-2)" "unprognostic (2.10e-1)" "prognostic favorable (4.07e-5)" "unprognostic (5.20e-2)" "unprognostic (2.48e-1)" "unprognostic (6.60e-2)" "unprognostic (7.29e-3)" 27.3 33.2 29.3 16.1 29.5 18.2 26.2 30.6 34.7 27.6 26.1 41.1 44.9 31.5 10.4 34.5 27.0 14.1 110.1 29.5 30.7 40.8 36.2 32.6 20.5 31.4 31.4 24.4 35.9 33.2 16.2 18.8 31.0 27.5 17.9 18.7 26.4 20.2 68.4 30.8 42.6 22.3 29.8 26.7 38.2 13.9 31.7 25.7 26.9 80.1 17.2 37.1 26.2 30.5 39.1 134.9 48.4 32.4 33.2 32.9 28.8 31.9 36.9 55.7 49.5 96.7 43.5 40.4 47.8 47.3 30.1 28.6 36.9 59.0 28.4 37.3 47.4 38.1 35.2 70.8 49.5 64.6 36.8 52.5 53.3 44.6 31.3 37.9 66.2 54.7 52.3 39.2 38.0 48.4 59.2 26.4 60.5 55.7 40.3 48.7 38.1 35.8 53.8 53.4 34.6 57.1 51.4 41.9 35.0 38.4 39.2 72.3 50.0 47.7 52.0 29.3 55.7 41.0 41.7 36.6 42.5 46.5 35.0 15.0 28.4 24.2 22.0 25.7 22.9 16.8 16.7 22.2 40.3 19.7 17.7 17.2 9.3 22.9 22.8 26.6 21.0 23.2 29.3 29.5 30.6 34.7 29.5 30.7 31.4 31.4 31.0 29.8 31.7 30.5 25.4 28.9 16.9 0.0 3.1 0.0 0.0 0.0 0.0 0.0 25.7 19.7 0.0 0.0 5.6 12.9 0.0 47.9 9.6 0.0 39.2 44.0 0.0 10.3 17.3 11.6 0.0 0.0 0.0 40.5 67.9 9.3 0.0 14.7 7.6 22.4 0.0 0.0 40.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 31.6 0.0 0.0 0.0 0.0 29.2 0.0 0.0 1.4 0.0 0.0 46.3 2.9 0.0 0.0 0.0 12.3 0.0 0.0 0.0 0.0 46.4 6.5 21.0 0.0 0.0 DMGDH ENSG00000132837 "Dimethylglycine dehydrogenase" Q9UI17 5 78997564-79236038 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 18 "kidney: 169.4;liver: 283.8" "Cell type enhanced" "Detected in many" "Early spermatids: 40.6;Hepatocytes: 104.2;Late spermatids: 33.1;Proximal tubular cells: 83.9" "Group enriched" "Detected in some" 12 "liver cancer: 15.6;renal cancer: 12.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 3.6;Hep G2: 7.6;hTEC/SVTERT24-B: 2.2;Karpas-707: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA036441, HPA036442, HPA077849" Enhanced Supported Mitochondria NA NA 680000 "Cluster 81: Kidney & Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA036441: AB_2675124, HPA036442: AB_10669792, HPA077849: AB_2686859" "unprognostic (3.11e-2)" "unprognostic (3.36e-1)" "unprognostic (6.70e-2)" "unprognostic (1.81e-1)" "unprognostic (3.15e-1)" "unprognostic (2.52e-3)" "prognostic favorable (5.32e-5)" "unprognostic (2.21e-1)" "unprognostic (3.05e-2)" "unprognostic (3.19e-2)" "unprognostic (1.07e-4)" "unprognostic (1.89e-1)" "prognostic favorable (1.17e-5)" "unprognostic (2.03e-2)" "unprognostic (9.75e-4)" "unprognostic (1.46e-1)" "unprognostic (2.26e-1)" 8.4 4.5 1.5 0.3 1.7 0.0 2.2 1.4 1.6 1.4 3.0 1.3 0.2 2.8 12.2 1.4 1.3 2.1 1.9 1.5 2.4 169.4 283.8 0.4 0.2 1.5 1.9 2.2 1.8 0.6 2.9 0.1 2.0 1.8 0.4 1.5 0.4 1.8 2.4 0.6 0.6 1.7 1.4 0.1 1.0 2.3 2.9 0.3 4.8 1.5 0.3 1.2 0.5 1.6 0.0 0.0 0.0 0.3 0.3 0.8 0.3 0.2 3.6 0.8 1.4 0.0 0.0 0.0 0.2 1.1 0.0 0.0 0.0 0.0 1.1 0.2 0.0 0.0 0.0 7.6 1.9 0.0 0.0 1.7 2.1 2.2 1.6 1.5 0.0 0.8 0.0 2.3 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 2.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.7 1.4 1.6 1.5 2.4 1.5 1.9 2.0 1.4 2.9 1.6 1.3 0.0 1.1 19.9 2.9 0.1 0.5 1.0 1.8 1.9 1.4 1.8 1.0 2.8 0.8 9.2 2.1 0.3 1.9 0.7 19.6 0.4 40.6 2.6 5.0 1.2 1.2 6.1 5.8 0.7 0.1 2.7 3.6 2.7 0.0 4.1 1.8 104.2 0.1 0.0 1.5 1.2 4.1 1.6 0.4 33.1 2.5 1.7 0.0 4.7 0.2 4.3 3.1 4.5 3.3 0.8 1.4 2.6 4.5 0.9 1.6 83.9 4.7 3.7 0.0 1.7 0.7 4.9 5.3 1.8 0.3 0.3 2.9 4.4 0.9 0.8 DNA2 "DNA2L, KIAA0083" ENSG00000138346 "DNA replication helicase/nuclease 2" P51530 10 68414064-68472121 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, Endonuclease, Helicase, Hydrolase, Multifunctional enzyme, Nuclease" "Disease variant, Dwarfism, Mental retardation, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 8.1" "Cell type enhanced" "Detected in many" "Erythroid cells: 33.2;Excitatory neurons: 14.1;Inhibitory neurons: 15.5;Oligodendrocytes: 18.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "NK-cell: 1.8" "Lineage enriched" "Detected in single" 5 "NK-cells: 1.8" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA037487, HPA057526" Approved Supported Mitochondria No Yes "Cluster 15: NK-cells - Transcription" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Mitochondria "HPA037487: AB_10672493, HPA057526: AB_2683456" "unprognostic (1.79e-1)" "unprognostic (1.35e-1)" "unprognostic (4.37e-3)" "unprognostic (4.60e-3)" "unprognostic (1.53e-1)" "unprognostic (1.86e-2)" "unprognostic (4.50e-5)" "unprognostic (3.36e-2)" "unprognostic (4.70e-2)" "unprognostic (3.72e-2)" "unprognostic (1.30e-2)" "unprognostic (3.29e-4)" "unprognostic (1.09e-10)" "unprognostic (3.43e-2)" "unprognostic (1.98e-1)" "unprognostic (9.36e-2)" "unprognostic (1.23e-2)" 1.3 0.9 1.9 2.8 2.1 4.6 1.8 2.5 3.6 1.4 1.0 2.3 2.1 1.1 0.9 1.9 0.9 0.9 1.8 1.8 1.9 2.6 4.2 1.8 5.2 2.3 1.9 1.2 1.6 0.4 1.5 1.6 2.4 1.9 2.8 5.3 1.6 0.4 1.6 1.8 3.2 1.1 1.6 2.1 1.9 2.9 2.1 8.1 1.0 0.9 4.2 1.4 1.4 3.2 25.6 13.0 29.0 20.7 3.2 2.2 20.4 12.4 10.3 17.4 21.2 31.1 16.1 26.1 4.6 3.8 6.7 15.2 16.8 6.5 20.7 16.2 12.6 15.8 8.5 12.3 0.9 27.7 16.4 1.8 2.6 12.3 3.6 4.5 7.9 17.0 23.6 22.8 10.1 9.0 42.8 19.8 20.5 10.9 24.0 33.1 20.0 8.4 7.5 11.7 13.1 15.7 16.9 21.4 4.2 20.1 16.5 11.6 3.4 6.6 20.5 8.5 23.8 11.5 13.9 38.3 5.7 26.1 8.9 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.1 0.1 0.0 1.8 0.0 0.0 0.1 0.0 1.9 2.1 2.5 3.6 1.8 1.9 2.3 1.9 2.4 1.6 2.1 3.2 1.0 6.4 1.1 4.9 1.3 2.3 0.9 1.7 2.8 2.5 2.3 1.4 10.5 2.8 1.1 1.8 6.2 3.9 2.2 1.7 0.0 0.8 2.2 2.0 1.4 2.0 1.2 33.2 14.1 0.9 4.8 2.0 2.6 2.8 0.0 6.0 0.7 4.6 2.2 0.0 15.5 1.8 0.0 1.3 0.7 3.7 0.6 1.5 0.0 4.7 0.5 0.5 2.1 5.5 18.4 0.7 0.1 0.7 7.4 2.5 2.4 0.6 0.8 4.3 0.0 2.4 1.1 9.1 12.2 4.7 1.7 1.2 1.6 0.7 3.7 1.0 DNAJC11 FLJ10737 ENSG00000007923 "DnaJ heat shock protein family (Hsp40) member C11" Q9NVH1 1 6634168-6701924 "Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023707, HPA028705" Uncertain Supported Mitochondria No No "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA023707: , HPA028705: AB_10603662" "unprognostic (3.74e-2)" "unprognostic (3.19e-2)" "unprognostic (4.06e-2)" "unprognostic (6.05e-3)" "unprognostic (9.55e-2)" "unprognostic (6.65e-2)" "unprognostic (4.38e-3)" "unprognostic (6.10e-2)" "unprognostic (6.34e-2)" "unprognostic (2.89e-1)" "unprognostic (1.45e-1)" "unprognostic (1.34e-1)" "prognostic favorable (2.63e-5)" "unprognostic (6.30e-2)" "unprognostic (1.76e-1)" "unprognostic (9.77e-2)" "unprognostic (1.04e-1)" 16.9 28.3 15.8 19.1 16.3 14.5 16.3 14.5 20.0 15.2 11.9 28.6 27.2 17.2 12.7 24.2 15.5 12.5 37.2 17.7 15.1 54.5 28.8 13.6 19.0 17.9 16.5 18.7 19.0 24.5 12.7 17.7 18.1 15.4 31.7 16.5 17.1 13.8 44.0 20.3 23.3 17.6 13.5 23.3 21.7 16.5 17.8 15.4 14.6 35.9 18.5 18.6 16.2 17.7 44.5 41.5 47.6 44.3 40.5 28.6 44.7 42.6 36.5 82.7 58.9 51.2 61.7 70.0 41.2 49.2 35.3 58.1 82.9 69.1 72.1 40.0 57.6 71.0 84.1 51.4 40.7 85.4 37.6 42.3 19.0 74.8 48.7 29.2 39.6 52.2 92.6 29.7 42.3 35.5 53.6 45.1 49.9 60.2 71.9 60.0 41.7 50.9 53.0 37.3 64.9 46.0 49.3 98.2 55.4 39.9 39.1 44.6 40.5 48.9 26.1 40.9 51.7 34.5 40.7 91.2 48.1 93.5 25.0 10.2 9.6 3.4 8.7 12.8 8.8 7.5 6.2 9.4 12.1 8.4 6.6 5.2 0.3 10.0 14.4 5.3 7.6 9.2 15.8 16.3 14.5 20.0 17.7 15.1 17.9 16.5 18.1 13.5 17.8 17.7 11.9 9.6 11.8 17.3 9.7 19.6 4.4 9.1 4.6 18.5 8.6 9.8 9.7 2.8 9.7 12.9 29.2 21.4 5.3 33.4 35.2 14.2 14.9 8.6 13.1 9.3 14.6 25.2 28.6 13.7 22.8 10.3 23.0 10.5 5.1 27.4 5.0 14.1 16.7 20.2 35.8 22.9 14.2 8.2 24.2 9.3 8.1 9.6 28.4 18.7 8.4 11.8 6.2 15.6 23.3 11.1 19.6 4.5 13.3 6.5 37.2 32.4 12.0 17.7 6.6 11.8 13.7 17.0 11.6 14.5 18.3 23.8 8.9 24.9 36.4 5.3 DNASE1L2 DNAS1L2 ENSG00000167968 "Deoxyribonuclease 1 like 2" Q92874 16 2235816-2238711 "Predicted secreted proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 45.8" "Cell type enhanced" "Detected in some" "Astrocytes: 2.9;Excitatory neurons: 2.5;Inhibitory neurons: 2.6;Ionocytes: 4.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" HPA044714 Uncertain Mitochondria "Secreted in other tissues" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 20: HeLa - Mitochondria" "Cluster 64: Astrocytes - Nervous system maintenance" Mitochondria "HPA044714: AB_10962870" "unprognostic (9.88e-2)" "unprognostic (1.11e-3)" "unprognostic (6.80e-4)" "unprognostic (4.29e-2)" "unprognostic (2.35e-1)" "unprognostic (1.55e-1)" "unprognostic (2.72e-2)" "unprognostic (2.50e-1)" "unprognostic (2.72e-1)" "unprognostic (1.86e-1)" "unprognostic (2.96e-3)" "unprognostic (2.17e-2)" "unprognostic (4.67e-4)" "unprognostic (1.40e-4)" "unprognostic (3.51e-1)" "unprognostic (2.28e-1)" "unprognostic (2.94e-4)" 0.9 1.1 4.8 0.4 5.2 0.5 1.2 7.3 8.4 1.8 2.0 1.0 0.5 1.1 0.2 0.9 1.2 0.3 0.9 4.2 4.5 4.6 1.7 0.9 0.4 6.1 4.5 2.0 1.9 0.1 4.7 0.7 6.4 2.3 0.1 1.1 0.8 0.1 0.7 45.8 1.0 0.1 3.7 2.6 1.0 1.5 4.9 0.6 6.0 0.1 0.8 0.9 1.6 7.6 1.4 2.9 1.2 1.3 1.0 0.5 5.0 0.5 0.3 1.1 0.6 3.2 3.0 1.9 1.5 0.1 0.4 0.5 0.4 0.2 0.1 3.8 2.8 0.8 5.6 0.7 0.1 0.9 3.0 0.6 1.0 0.8 0.2 1.1 0.2 2.1 2.7 2.8 0.4 3.4 2.7 5.6 1.2 0.4 1.9 5.0 1.4 2.7 0.6 0.6 2.5 1.3 0.7 1.1 2.1 0.3 4.5 2.0 0.1 2.4 3.1 1.4 1.0 6.8 3.5 1.8 0.8 1.8 1.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 4.8 5.2 7.3 8.4 4.2 4.5 6.1 4.5 6.4 3.7 4.9 7.6 0.2 0.0 0.6 2.9 0.1 0.1 0.1 0.4 0.0 0.7 0.7 0.5 0.7 1.5 0.1 0.0 0.0 0.1 0.2 0.5 0.0 0.1 0.1 0.2 1.0 0.3 0.0 0.0 2.5 0.0 0.1 0.1 1.1 0.4 0.0 0.6 0.4 0.4 0.1 1.7 2.6 0.1 4.1 0.0 0.0 0.1 0.6 0.1 0.0 1.0 0.1 0.9 0.0 1.0 1.8 0.0 0.1 0.0 0.5 0.2 0.8 0.1 0.1 1.8 0.0 0.0 0.2 0.1 0.5 0.0 0.1 0.0 0.2 0.3 0.3 0.1 DTNB ENSG00000138101 "Dystrobrevin beta" O60941 2 25377198-25673647 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 36.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 176.8;Inhibitory neurons: 214.1;Oligodendrocyte precursor cells: 137.7;Oligodendrocytes: 343.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" HPA061357 Uncertain Approved Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA061357: AB_2684489" "unprognostic (1.14e-1)" "unprognostic (1.39e-2)" "unprognostic (3.17e-2)" "unprognostic (7.40e-2)" "unprognostic (1.17e-1)" "unprognostic (1.16e-2)" "prognostic unfavorable (2.54e-4)" "unprognostic (1.78e-2)" "unprognostic (3.67e-3)" "unprognostic (3.98e-2)" "unprognostic (9.45e-2)" "unprognostic (4.67e-2)" "prognostic favorable (3.47e-4)" "unprognostic (1.86e-1)" "unprognostic (1.40e-1)" "unprognostic (3.16e-2)" "unprognostic (6.49e-2)" 2.1 2.1 7.8 1.6 6.7 2.9 9.7 3.4 12.1 4.2 0.0 1.7 1.2 2.8 10.1 4.5 4.6 3.3 2.0 12.4 3.6 4.2 3.4 4.3 2.5 4.9 1.7 4.4 7.7 9.9 5.8 1.9 4.5 8.4 1.0 5.0 36.0 5.1 2.7 4.5 1.6 1.2 0.1 2.7 5.6 6.7 2.9 4.0 11.1 1.5 1.9 3.5 4.0 5.6 10.7 9.1 6.6 7.5 4.0 5.2 0.2 3.2 4.2 4.0 5.3 3.5 2.6 5.5 1.3 2.5 5.0 3.7 4.6 13.1 2.2 8.2 11.1 4.5 2.9 10.0 2.9 5.4 4.1 3.6 10.9 4.2 7.2 4.9 5.5 10.5 0.4 8.0 3.0 10.9 8.5 4.6 7.3 2.9 5.4 7.0 11.5 9.7 4.9 9.7 8.9 13.7 10.3 16.2 12.9 3.6 8.7 3.3 2.3 1.6 7.3 2.4 5.7 14.6 6.8 10.0 4.6 9.5 5.7 0.4 1.6 5.7 4.1 0.9 4.4 4.4 5.0 3.7 0.5 5.8 5.0 3.3 3.2 4.1 0.4 0.9 5.2 2.0 7.8 6.7 3.4 12.1 12.4 3.6 4.9 1.7 4.5 0.1 2.9 5.6 3.9 9.6 12.8 53.2 12.6 8.0 26.6 16.4 44.3 9.4 20.3 18.9 2.3 7.2 9.3 14.7 6.2 3.7 4.2 0.9 11.7 4.0 3.1 7.2 4.2 4.7 3.0 4.4 176.8 11.6 1.5 3.2 15.8 12.1 1.3 4.6 5.0 5.6 33.6 21.9 214.1 2.8 14.2 7.8 1.7 6.9 1.5 4.9 12.4 83.4 3.2 18.5 7.2 137.7 343.3 9.5 1.4 2.6 8.7 17.9 0.3 9.3 2.2 9.9 6.6 1.9 3.2 12.6 27.9 15.7 2.0 2.1 10.8 2.3 1.3 17.7 DTYMK "CDC8, TMPK, TYMK" ENSG00000168393 "Deoxythymidylate kinase" P23919 2 241675747-241686944 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Nucleotide biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 108.6;Extravillous trophoblasts: 149.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042593, HPA042719" Approved Approved Mitochondria NA NA 7000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Mitochondria "HPA042593: AB_10959590, HPA042719: AB_10960633" "unprognostic (1.90e-1)" "unprognostic (6.95e-2)" "unprognostic (4.14e-1)" "unprognostic (8.61e-2)" "unprognostic (1.89e-1)" "unprognostic (9.45e-2)" "prognostic unfavorable (1.73e-5)" "unprognostic (1.44e-2)" "unprognostic (2.64e-2)" "unprognostic (5.50e-2)" "unprognostic (2.60e-2)" "unprognostic (6.94e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (7.13e-2)" "unprognostic (6.81e-2)" "unprognostic (5.07e-2)" "unprognostic (9.19e-2)" 12.2 16.0 15.6 15.6 17.1 37.0 11.8 16.2 19.8 11.2 16.5 15.1 13.2 10.8 6.1 19.1 10.2 8.6 10.6 14.5 15.0 14.9 18.8 9.7 24.8 16.8 16.0 8.2 9.5 7.5 5.0 11.1 16.1 11.1 12.2 4.3 9.8 7.4 8.1 18.8 14.0 13.4 15.3 17.2 13.3 8.2 16.8 24.1 8.7 6.4 19.2 10.6 11.2 17.2 102.6 112.3 93.6 120.1 30.2 33.3 103.2 82.1 63.2 110.8 125.6 54.8 120.1 48.3 24.6 66.8 126.8 84.4 87.8 102.2 56.7 118.8 104.6 103.9 88.3 105.1 26.3 69.1 83.1 23.7 27.3 102.7 42.4 32.1 104.8 74.4 123.6 38.4 114.1 112.6 132.2 125.0 100.7 113.1 94.2 111.4 139.8 71.8 62.3 59.5 115.0 74.0 53.4 81.5 67.9 27.0 74.2 120.0 66.5 147.5 110.4 99.0 152.5 47.3 49.1 144.6 122.4 112.2 184.9 20.5 26.2 17.4 30.4 46.7 29.6 35.6 28.5 32.6 19.7 36.7 28.1 25.0 4.2 32.6 37.1 38.5 42.1 28.5 15.6 17.1 16.2 19.8 14.5 15.0 16.8 16.0 16.1 15.3 16.8 17.2 28.9 9.6 5.8 8.1 21.4 15.2 17.7 47.7 16.5 19.1 36.3 44.8 11.0 24.3 22.2 25.8 2.1 79.5 24.0 22.9 21.5 39.6 2.1 17.6 25.0 29.2 14.4 108.6 3.3 34.1 149.1 26.9 25.5 22.3 15.2 52.3 23.9 22.3 84.9 5.0 4.7 35.7 36.7 17.0 13.9 2.1 16.4 21.7 23.2 5.6 39.3 23.0 38.1 6.0 9.2 33.7 10.6 19.2 37.6 21.7 12.7 37.7 12.9 17.4 26.3 21.4 31.2 27.5 63.4 32.6 11.9 27.5 17.4 28.2 52.2 19.5 ECH1 HPXEL ENSG00000104823 "Enoyl-CoA hydratase 1" Q13011 19 38815422-38831841 "Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 749.9;skeletal muscle: 906.9" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 796.9;Proximal tubular cells: 880.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002907, HPA005835" Supported Supported Supported Mitochondria No No 720000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA002907: AB_1847964, HPA005835: AB_1847965" "unprognostic (1.91e-1)" "unprognostic (3.03e-2)" "unprognostic (3.64e-2)" "unprognostic (6.43e-2)" "unprognostic (5.73e-3)" "unprognostic (6.90e-2)" "unprognostic (1.28e-1)" "unprognostic (1.79e-1)" "unprognostic (2.43e-1)" "unprognostic (5.86e-2)" "unprognostic (2.24e-1)" "unprognostic (3.37e-1)" "unprognostic (7.01e-2)" "prognostic unfavorable (2.23e-4)" "unprognostic (3.54e-1)" "unprognostic (3.52e-1)" "unprognostic (1.74e-2)" 216.0 343.0 51.2 47.6 53.7 62.3 194.2 54.1 60.3 124.9 58.6 232.9 93.5 115.3 32.3 168.4 114.0 66.8 749.9 49.3 52.5 271.6 556.1 122.1 67.8 51.8 51.8 107.2 141.4 56.0 77.1 67.1 53.4 99.5 99.9 12.8 138.6 43.3 906.9 149.0 167.4 59.7 50.6 192.3 180.5 100.7 55.0 51.0 117.9 455.1 65.7 142.4 132.4 53.3 64.0 273.8 42.0 68.8 161.0 82.0 61.8 31.7 53.2 26.6 27.1 178.8 124.8 98.6 117.2 72.8 24.1 30.1 70.9 72.9 21.1 345.3 37.7 120.7 76.5 146.1 161.3 131.9 116.9 109.0 186.6 35.1 61.2 52.3 63.4 127.3 58.4 160.8 59.6 120.0 91.8 82.2 27.8 278.8 65.9 101.8 126.2 199.0 168.7 142.6 51.4 67.2 161.0 77.1 86.5 27.3 106.4 288.4 53.7 45.5 39.3 46.5 29.6 121.0 153.2 96.4 71.4 164.9 90.7 316.1 312.9 268.0 253.6 248.2 237.2 368.4 243.5 249.1 308.6 361.3 216.5 242.4 41.6 342.7 212.8 221.5 391.8 541.8 51.2 53.7 54.1 60.3 49.3 52.5 51.8 51.8 53.4 50.6 55.0 53.3 125.4 86.6 104.7 13.1 111.1 82.2 220.0 320.8 80.8 22.4 124.0 143.8 302.7 205.9 203.2 145.3 16.7 796.9 103.4 257.7 510.6 195.4 64.5 95.7 56.9 96.4 189.2 99.9 7.1 90.1 370.6 104.1 112.7 77.0 120.9 177.6 90.7 549.4 277.6 37.0 8.6 298.9 193.3 99.0 85.2 56.7 130.8 97.5 145.9 8.4 205.1 53.0 113.3 7.1 16.0 97.0 257.5 143.0 122.1 100.1 383.0 880.0 182.6 21.4 78.9 88.4 119.7 73.3 51.3 121.6 90.8 580.9 118.6 624.2 350.0 218.1 ECHDC2 FLJ10948 ENSG00000121310 "Enoyl-CoA hydratase domain containing 2" Q86YB7 1 52895910-52927212 "Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 174.3" "Cell type enhanced" "Detected in all" "Hepatocytes: 875.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 15.8;HHSteC: 11.0;THP-1: 10.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026731, HPA026768" Enhanced Approved Mitochondria NA NA 240000 "Cluster 35: T-regs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 2: Hepatocytes - Metabolism" Mitochondria "HPA026731: AB_1847969, HPA026768: AB_1847970" "unprognostic (2.73e-3)" "unprognostic (1.52e-2)" "unprognostic (4.08e-2)" "unprognostic (3.76e-1)" "unprognostic (7.67e-2)" "prognostic favorable (6.65e-4)" "unprognostic (1.51e-3)" "unprognostic (1.40e-3)" "unprognostic (6.11e-2)" "unprognostic (7.16e-2)" "unprognostic (2.98e-3)" "unprognostic (4.40e-2)" "unprognostic (5.47e-2)" "unprognostic (5.12e-2)" "unprognostic (2.93e-1)" "unprognostic (3.62e-1)" "prognostic favorable (2.70e-4)" 24.1 35.2 5.9 1.2 6.0 2.7 24.9 7.5 7.9 18.1 7.2 18.0 16.7 17.2 5.5 28.2 23.1 5.1 27.6 5.6 5.7 50.6 174.3 12.8 2.3 5.6 5.8 29.1 23.2 14.3 14.6 4.5 5.7 24.0 3.5 5.0 19.0 8.4 29.9 17.1 17.3 2.4 5.5 9.3 29.1 7.0 6.1 3.0 38.9 26.8 1.5 18.2 16.8 5.7 0.0 1.8 0.0 0.0 1.1 0.5 15.8 1.2 7.6 1.6 2.4 0.0 1.5 0.0 7.7 1.2 0.0 0.8 0.0 1.2 0.3 0.0 8.1 0.0 3.1 3.6 11.0 0.0 1.8 1.6 3.2 1.0 1.1 2.4 4.5 0.0 1.2 0.2 0.0 4.2 0.0 0.9 0.2 7.0 1.7 0.0 0.2 0.7 5.2 6.4 0.8 0.3 2.3 6.3 0.1 0.9 1.3 10.2 2.3 0.0 0.0 0.7 0.2 0.3 0.6 0.0 0.5 0.0 0.4 0.0 2.1 1.8 12.1 1.4 9.1 6.9 9.9 11.4 9.5 3.3 10.7 6.6 0.4 6.1 0.8 2.4 13.6 4.0 5.9 6.0 7.5 7.9 5.6 5.7 5.6 5.8 5.7 5.5 6.1 5.7 23.9 54.5 92.0 161.3 17.9 30.7 85.6 67.2 83.1 32.3 96.4 86.7 61.5 153.0 71.1 86.5 327.4 206.0 26.7 96.4 178.1 59.3 150.2 54.9 19.5 18.7 52.1 29.9 26.0 59.4 18.0 64.6 94.3 41.3 29.8 50.6 30.4 875.3 31.8 42.1 34.9 78.3 40.7 27.6 13.8 180.6 154.1 12.8 40.9 51.5 7.6 60.0 23.7 54.8 6.9 44.6 115.7 112.5 10.0 66.5 172.6 284.7 62.5 160.6 19.7 118.3 39.5 17.0 16.7 66.9 29.5 124.0 36.1 23.7 64.7 80.0 ECHS1 SCEH ENSG00000127884 "Enoyl-CoA hydratase, short chain 1" P30084 10 133362485-133373354 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Lyase "Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1128.7" "Cell type enhanced" "Detected in all" "Hepatocytes: 1476.3;Proximal tubular cells: 2336.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003783, HPA021995, HPA022476" Enhanced Enhanced Mitochondria NA NA 1200000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "CAB003783: , HPA021995: AB_1847974, HPA022476: AB_1847975" "unprognostic (3.68e-1)" "unprognostic (2.46e-3)" "unprognostic (9.57e-2)" "unprognostic (4.70e-2)" "unprognostic (1.59e-1)" "unprognostic (3.14e-1)" "unprognostic (2.51e-3)" "unprognostic (2.30e-1)" "unprognostic (1.82e-2)" "unprognostic (2.28e-2)" "unprognostic (1.60e-1)" "unprognostic (1.27e-1)" "prognostic favorable (8.57e-5)" "unprognostic (2.84e-2)" "unprognostic (1.19e-2)" "unprognostic (3.04e-2)" "unprognostic (2.50e-2)" 302.4 127.1 127.7 53.7 127.8 43.9 116.9 131.3 136.1 59.8 149.7 143.1 171.6 47.0 89.3 107.9 90.5 66.7 226.4 133.1 129.9 481.7 1128.7 48.5 52.4 129.4 129.9 71.3 96.8 98.7 74.3 73.6 128.8 102.0 104.6 39.8 163.4 123.2 294.3 68.2 153.6 59.4 130.3 48.4 84.5 52.6 134.6 40.0 88.5 271.6 59.0 87.4 57.8 136.0 185.1 229.2 120.4 303.4 173.0 111.4 110.5 132.2 175.9 183.2 154.1 509.5 174.0 139.2 111.9 151.4 94.4 167.7 160.2 136.1 132.0 107.4 281.2 138.5 128.1 367.2 145.0 180.4 93.5 124.5 115.9 121.2 153.6 160.8 165.1 98.3 127.8 117.4 181.6 443.9 90.7 352.0 84.4 289.8 272.1 152.8 146.4 74.6 227.8 236.0 78.1 123.4 137.0 224.1 178.9 69.4 174.8 171.5 132.1 81.3 115.9 169.9 177.4 87.0 58.8 159.8 192.4 98.8 68.7 96.1 184.7 86.8 105.5 212.2 137.6 178.7 117.8 115.8 242.6 148.9 119.3 115.8 19.8 166.0 168.1 104.9 123.0 233.0 127.7 127.8 131.3 136.1 133.1 129.9 129.4 129.9 128.8 130.3 134.6 136.0 99.2 44.8 82.7 16.3 60.5 68.2 86.9 271.8 62.6 57.0 98.5 119.6 255.2 210.1 161.5 174.7 6.2 470.2 34.0 298.6 565.4 162.8 29.9 148.9 92.7 71.4 131.7 72.2 11.6 101.1 163.5 92.5 87.7 226.4 91.2 120.0 88.5 1476.3 221.1 45.4 11.0 223.0 175.0 92.1 61.5 39.1 77.6 88.0 135.2 10.3 113.0 145.2 45.3 10.6 24.3 107.8 248.6 91.7 57.5 88.0 486.2 2336.5 93.2 55.2 85.5 57.0 98.8 52.9 66.1 125.2 76.3 299.1 62.5 220.0 317.2 127.8 ECI1 DCI ENSG00000167969 "Enoyl-CoA delta isomerase 1" P42126 16 2239402-2252300 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 301.3;Hepatocytes: 246.5;Proximal tubular cells: 272.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041746, HPA043227" Enhanced Enhanced Mitochondria NA NA 7300000 "Cluster 26: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA041746: AB_10960693, HPA043227: AB_10960273" "unprognostic (4.99e-2)" "prognostic favorable (3.04e-5)" "unprognostic (3.75e-1)" "unprognostic (2.92e-3)" "unprognostic (8.90e-2)" "unprognostic (2.85e-2)" "prognostic favorable (1.07e-4)" "unprognostic (1.98e-1)" "unprognostic (2.17e-1)" "unprognostic (5.14e-3)" "unprognostic (6.32e-2)" "unprognostic (2.66e-2)" "prognostic favorable (8.99e-8)" "unprognostic (2.61e-2)" "unprognostic (3.31e-1)" "unprognostic (1.97e-1)" "unprognostic (6.08e-3)" 51.5 57.3 35.9 12.7 39.2 19.6 52.0 38.6 45.9 46.2 61.6 74.0 59.9 44.9 10.6 57.0 50.7 11.3 189.7 32.1 38.0 123.2 235.7 37.2 13.8 39.1 37.8 38.6 74.7 43.8 50.4 14.6 35.0 56.6 15.0 12.8 78.7 24.2 220.6 49.7 58.8 9.3 37.3 35.3 69.5 18.2 42.0 13.4 105.0 87.8 9.5 50.3 43.6 36.5 29.5 68.0 25.7 107.4 9.6 13.6 96.6 29.5 19.1 23.1 33.7 120.0 88.0 42.3 71.2 17.7 16.9 71.6 29.6 27.5 3.2 74.2 157.1 12.9 61.7 151.7 87.3 38.6 6.0 25.2 63.1 18.9 41.7 16.4 23.6 1.1 71.7 87.1 8.0 119.1 4.0 57.8 60.1 46.8 68.8 134.3 27.7 207.1 45.5 32.5 88.8 56.2 70.0 131.4 92.7 12.6 84.7 67.7 19.6 18.4 68.0 19.9 33.0 95.8 61.0 72.2 23.9 35.4 26.2 1.7 3.6 1.6 1.9 3.8 3.1 4.4 2.8 1.6 3.0 4.9 3.4 2.9 2.0 3.6 2.5 3.6 4.0 0.8 35.9 39.2 38.6 45.9 32.1 38.0 39.1 37.8 35.0 37.3 42.0 36.5 47.1 3.2 28.2 13.4 28.0 21.3 115.6 11.3 21.1 53.2 77.2 95.1 92.3 94.4 15.0 77.3 43.8 179.6 20.5 151.7 301.3 35.1 10.9 128.2 54.8 28.2 45.5 61.7 4.2 36.9 80.7 33.1 33.1 122.8 5.7 62.2 34.2 246.5 47.9 21.9 6.7 105.9 20.3 31.0 23.8 5.3 24.5 29.8 39.2 4.7 17.5 89.9 5.2 13.0 10.0 33.2 91.1 24.0 36.8 72.8 176.1 272.3 14.6 77.6 0.0 73.4 42.7 6.3 19.6 32.9 22.3 109.9 21.7 50.2 104.7 110.5 EFEMP1 "DHRD, FBLN3, FBNL, MTLV, S1-5" ENSG00000115380 "EGF containing fibulin extracellular matrix protein 1" Q12805 2 55865967-55924139 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 367.7;Cytotrophoblasts: 1365.8;Fibroblasts: 309.7;Syncytiotrophoblasts: 889.6" "Cancer enhanced" "Detected in all" "glioma: 94.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HSkMC: 953.6;hTERT-RPE1: 2226.5;HUVEC TERT2: 4270.9;TIME: 3554.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016368, HPA049806, HPA070841, HPA071588" Supported Supported Mitochondria "Secreted to extracellular matrix" NA NA 1900000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "CAB016368: AB_2277777, HPA049806: , HPA070841: AB_2686319, HPA071588: " "unprognostic (8.21e-2)" "unprognostic (7.68e-2)" "unprognostic (9.01e-3)" "prognostic unfavorable (4.72e-4)" "unprognostic (3.43e-2)" "unprognostic (1.73e-2)" "unprognostic (4.86e-2)" "unprognostic (1.38e-1)" "unprognostic (3.46e-1)" "unprognostic (9.07e-2)" "unprognostic (1.55e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.89e-8)" "unprognostic (3.15e-3)" "unprognostic (4.94e-2)" "unprognostic (3.09e-1)" "prognostic unfavorable (6.68e-5)" 240.5 55.7 57.0 57.2 82.8 0.2 115.3 57.1 88.8 54.9 180.7 74.6 22.5 73.2 128.4 51.5 134.8 140.4 187.8 47.5 75.6 57.4 12.9 150.1 27.2 80.8 121.1 175.1 29.2 17.6 22.6 329.7 65.5 58.4 91.0 42.8 87.7 161.2 14.7 55.2 45.3 93.5 72.2 42.4 46.9 8.0 71.0 16.8 139.1 93.8 21.2 203.9 77.3 71.9 358.4 3.1 8.5 0.3 320.9 217.1 0.8 208.1 233.7 25.2 20.5 0.0 18.0 0.5 140.4 234.3 22.1 323.4 1.6 234.6 8.9 1.0 1.0 0.3 87.4 0.2 843.2 0.3 0.6 953.6 117.5 21.9 260.9 2226.5 4270.9 0.5 1.2 0.2 99.2 36.7 2.6 0.5 4.2 0.1 0.8 0.2 0.3 0.9 9.8 7.3 2.0 0.4 284.6 105.0 0.7 8.1 289.8 1.5 3554.3 1.5 107.5 397.9 138.5 13.7 0.5 1.4 73.1 0.3 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 57.0 82.8 57.1 88.8 47.5 75.6 80.8 121.1 65.5 72.2 71.0 71.9 26.6 250.0 109.1 234.1 0.1 79.4 79.1 367.7 42.1 2.8 6.2 78.2 12.5 12.8 98.2 27.6 0.0 1365.8 0.4 0.0 9.8 36.2 0.5 2.2 38.9 73.5 0.0 0.0 1.0 25.6 173.0 309.7 6.1 2.1 2.5 3.9 48.5 0.7 94.9 0.0 4.7 0.0 40.7 0.8 33.9 0.9 42.6 3.2 17.8 6.5 0.6 137.3 0.0 2.5 0.8 2.8 0.0 0.0 1.5 24.2 0.0 14.7 88.8 4.7 0.0 7.0 28.7 0.4 1.8 6.0 31.7 889.6 5.0 61.3 0.0 6.2 ETFA "EMA, GA2, MADD" ENSG00000140374 "Electron transfer flavoprotein subunit alpha" P13804 15 76215353-76311472 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport" "Disease variant, Glutaricaciduria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 389.7;tongue: 493.5" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 402.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018990, HPA018993, HPA018996, HPA024089" Enhanced Enhanced Mitochondria NA NA 680000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA018990: AB_1848277, HPA018993: AB_1848275, HPA018996: AB_1848276, HPA024089: AB_1848278" "unprognostic (3.44e-3)" "unprognostic (1.50e-1)" "unprognostic (2.29e-1)" "unprognostic (2.26e-1)" "unprognostic (3.71e-3)" "unprognostic (5.99e-2)" "unprognostic (6.81e-3)" "unprognostic (3.02e-1)" "unprognostic (5.01e-2)" "unprognostic (6.01e-2)" "unprognostic (3.38e-3)" "unprognostic (1.99e-1)" "prognostic favorable (5.04e-8)" "unprognostic (2.87e-1)" "unprognostic (4.90e-2)" "unprognostic (9.22e-2)" "unprognostic (2.90e-2)" 93.0 112.3 33.8 55.0 36.0 63.0 70.4 36.0 54.6 38.7 40.3 131.4 135.6 27.0 30.6 85.1 30.1 44.7 243.0 34.2 37.6 180.0 389.7 39.0 60.9 35.6 35.7 25.6 81.6 71.0 13.9 70.9 36.0 42.2 123.5 34.3 49.3 38.2 300.8 40.1 116.3 65.7 35.5 38.8 67.7 28.4 38.2 54.5 38.7 493.5 65.9 74.0 33.1 36.9 122.4 196.7 128.2 134.8 141.7 149.1 201.0 144.4 166.2 183.0 162.8 175.3 221.3 203.5 141.3 144.3 138.5 304.6 502.7 200.2 211.9 245.8 98.0 222.2 131.4 205.2 114.7 214.5 158.7 112.7 185.9 93.1 153.5 100.0 187.8 64.7 214.1 205.2 190.3 191.2 44.9 178.2 99.9 225.3 58.4 192.8 158.6 272.8 202.1 386.9 133.3 67.2 218.2 492.2 205.0 294.4 254.1 223.4 111.4 178.2 119.5 157.0 177.4 99.0 221.0 255.9 127.8 281.1 128.5 50.0 120.3 82.7 65.4 110.3 61.7 77.3 60.6 67.6 159.4 67.3 48.8 60.1 30.2 122.9 96.1 63.4 95.8 141.9 33.8 36.0 36.0 54.6 34.2 37.6 35.6 35.7 36.0 35.5 38.2 36.9 65.7 57.7 41.6 45.1 54.3 53.4 110.8 151.5 44.9 13.1 47.2 46.4 352.9 65.8 84.5 36.8 22.9 277.4 61.1 250.9 209.4 106.5 11.7 29.5 45.1 51.8 65.4 117.8 26.0 84.1 180.8 66.8 90.2 37.0 38.6 53.1 48.9 348.8 132.3 53.8 31.5 141.6 89.5 79.0 84.5 7.9 59.4 103.0 56.9 28.1 129.0 26.7 85.5 37.2 46.9 92.1 176.2 58.3 87.8 92.4 231.1 402.9 50.2 20.4 46.0 44.0 113.7 66.4 40.5 79.5 57.1 300.2 55.5 123.4 187.3 162.0 ETFB ENSG00000105379 "Electron transfer flavoprotein subunit beta" P38117 19 51345169-51366388 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport" "Disease variant, Glutaricaciduria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 493.6" "Cell type enhanced" "Detected in all" "Hepatocytes: 1105.3;Proximal enterocytes: 710.7;Proximal tubular cells: 1118.7" "Cancer enhanced" "Detected in all" "liver cancer: 53.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 1693.9;OE19: 770.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018910, HPA018921, HPA018923" Supported Enhanced Mitochondria NA NA 170000 "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA018910: AB_1848280, HPA018921: AB_1848281, HPA018923: AB_1848282" "unprognostic (1.44e-1)" "prognostic favorable (6.45e-4)" "unprognostic (8.66e-2)" "unprognostic (3.08e-1)" "unprognostic (1.77e-1)" "unprognostic (3.94e-2)" "unprognostic (3.20e-1)" "unprognostic (6.93e-3)" "unprognostic (2.63e-2)" "unprognostic (7.79e-2)" "unprognostic (1.23e-1)" "unprognostic (4.75e-1)" "prognostic favorable (6.45e-5)" "unprognostic (2.19e-1)" "unprognostic (2.54e-1)" "unprognostic (4.83e-1)" "unprognostic (1.99e-1)" 159.1 171.5 121.1 44.0 134.4 70.2 115.3 134.8 145.5 55.7 123.0 97.6 136.3 48.9 16.9 140.7 53.3 62.7 387.8 112.8 120.6 144.5 493.6 50.4 58.2 129.8 124.8 55.2 81.9 106.3 73.1 39.0 125.7 55.2 41.2 24.1 172.2 37.9 280.7 79.0 129.7 31.7 119.9 64.5 90.0 53.6 132.4 81.4 70.3 280.3 36.9 65.6 69.0 137.0 118.9 304.3 41.3 113.9 129.4 150.4 65.6 82.4 61.0 63.5 63.1 257.3 192.1 121.5 80.2 129.8 33.8 104.0 83.3 171.1 19.2 182.0 323.3 98.1 188.9 1693.9 141.8 92.1 67.6 235.3 50.3 86.1 88.2 79.2 54.9 115.0 146.6 130.2 83.2 243.7 95.2 86.2 26.7 770.2 372.0 104.5 114.4 224.6 88.5 135.7 91.7 44.5 184.5 49.9 94.4 29.4 130.3 86.3 77.8 65.9 67.6 71.4 73.3 195.8 130.0 109.8 335.0 135.1 172.5 127.7 190.1 119.6 104.3 212.3 137.4 281.6 156.0 134.2 225.3 303.1 163.6 136.0 97.8 205.3 165.7 265.1 225.7 140.5 121.1 134.4 134.8 145.5 112.8 120.6 129.8 124.8 125.7 119.9 132.4 137.0 90.9 80.1 93.8 15.3 75.6 65.0 114.9 196.4 55.2 77.1 129.9 170.1 243.8 234.4 122.5 121.4 31.3 240.7 58.7 440.9 571.3 188.0 139.2 67.5 70.2 76.2 168.4 120.0 4.1 140.5 206.6 93.8 128.9 48.2 88.8 63.2 144.9 1105.3 217.5 43.7 4.2 335.2 158.7 147.7 73.4 354.4 107.5 86.9 286.4 5.6 95.2 158.8 50.4 7.1 18.9 155.4 339.4 114.3 69.9 74.9 710.7 1118.7 118.8 67.9 98.6 87.4 144.5 71.0 52.8 135.3 63.6 160.1 74.0 217.3 354.4 140.3 ETHE1 "HSCO, YF13H12" ENSG00000105755 "ETHE1 persulfide dioxygenase" O95571 19 43506719-43527230 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 256.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1037.7;Paneth cells: 788.4;Proximal enterocytes: 376.3;Undifferentiated cells: 447.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 222.6;OE19: 360.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028360, HPA029028, HPA029029" Enhanced Enhanced Mitochondria No No "Cluster 28: Myeloid DCs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA028360: AB_10599297, HPA029028: AB_10602092, HPA029029: AB_10601998" "unprognostic (8.04e-2)" "unprognostic (3.33e-1)" "unprognostic (1.50e-2)" "unprognostic (2.45e-1)" "unprognostic (8.34e-2)" "unprognostic (1.25e-2)" "unprognostic (2.58e-1)" "prognostic unfavorable (9.58e-4)" "unprognostic (7.75e-2)" "unprognostic (2.28e-1)" "unprognostic (5.47e-2)" "unprognostic (3.24e-1)" "unprognostic (1.01e-1)" "unprognostic (5.27e-2)" "unprognostic (1.75e-1)" "unprognostic (9.72e-3)" "unprognostic (2.73e-2)" 24.4 27.9 16.1 34.8 17.0 45.8 26.7 16.5 17.3 28.7 15.8 256.1 85.5 18.3 29.8 81.0 20.6 21.0 18.8 15.6 17.4 40.4 52.7 30.5 23.4 17.3 17.2 13.5 28.9 16.1 19.1 26.3 16.6 27.1 226.6 3.2 40.1 18.5 22.8 27.2 77.0 35.6 17.1 27.8 37.8 3.0 18.2 19.8 24.1 21.9 41.7 34.4 39.1 17.2 54.1 68.9 14.1 49.6 75.1 50.9 5.5 82.1 222.6 69.8 71.1 21.1 54.3 0.2 60.0 79.8 22.2 42.9 20.6 123.4 19.6 26.2 6.2 13.8 29.7 59.2 34.0 19.3 18.4 52.2 95.1 26.9 76.0 92.2 52.0 49.8 9.0 87.6 35.1 35.7 22.2 18.9 3.8 360.5 32.9 26.6 6.1 12.0 153.0 110.9 0.2 16.6 20.8 74.8 50.6 23.6 22.4 34.3 41.6 10.9 46.9 13.1 15.3 23.1 20.2 1.4 48.4 83.8 57.7 24.2 63.3 1.6 41.1 34.5 48.3 20.5 47.6 39.4 95.8 7.5 36.4 35.0 2.1 29.3 22.8 17.9 50.4 40.2 16.1 17.0 16.5 17.3 15.6 17.4 17.3 17.2 16.6 17.1 18.2 17.2 32.0 22.4 23.4 3.9 25.5 34.5 82.2 242.5 57.5 9.8 85.8 95.2 9.8 47.1 84.5 55.2 0.0 191.6 38.0 1037.7 54.8 71.7 0.9 31.0 41.2 44.9 63.7 17.4 6.2 63.6 95.7 42.1 53.5 68.2 38.0 12.6 42.1 89.2 115.1 5.0 6.8 324.2 79.3 105.0 78.5 2.1 17.7 74.6 80.0 3.7 78.5 11.7 63.8 4.0 5.6 102.7 788.4 16.1 34.9 75.0 376.3 136.4 23.1 5.8 19.7 32.0 45.1 2.1 6.2 82.8 23.2 92.5 50.4 15.8 447.5 146.5 EXOG "ENDOGL1, ENDOGL2, ENGL, ENGL-a, ENGL-b" ENSG00000157036 "Exo/endonuclease G" Q9Y2C4 3 38496127-38542161 "Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 59.8;Rod photoreceptor cells: 78.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012531, HPA071050" Enhanced Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 52: Non-specific - Transcription" Mitochondria "HPA012531: AB_2732403, HPA071050: " "unprognostic (2.88e-1)" "unprognostic (5.81e-3)" "unprognostic (3.55e-3)" "unprognostic (2.77e-1)" "unprognostic (8.32e-3)" "unprognostic (8.90e-3)" "unprognostic (4.78e-4)" "unprognostic (3.59e-2)" "unprognostic (3.99e-2)" "unprognostic (3.10e-2)" "prognostic favorable (1.92e-5)" "prognostic unfavorable (4.90e-4)" "unprognostic (6.51e-2)" "unprognostic (1.64e-2)" "unprognostic (4.79e-2)" "unprognostic (1.10e-1)" "unprognostic (2.78e-2)" 3.9 5.1 5.5 4.0 5.4 3.9 3.4 7.9 7.0 5.2 3.4 4.9 2.0 4.7 3.5 2.6 3.8 3.5 12.9 5.9 5.1 3.7 3.4 3.8 6.0 5.1 5.7 3.9 3.9 3.3 5.6 2.9 4.5 4.8 3.2 5.3 3.2 3.6 3.2 1.9 4.4 4.5 4.1 5.5 3.6 3.9 5.9 5.0 4.5 3.2 4.7 4.4 3.5 6.4 4.3 7.6 8.7 7.6 5.7 8.4 3.5 13.9 8.7 11.6 12.9 6.8 4.3 15.1 3.5 5.5 3.3 4.3 11.0 4.7 9.8 17.5 10.2 11.4 12.7 7.6 7.0 12.7 9.5 6.4 5.2 10.3 5.4 5.5 16.2 8.6 5.2 9.9 18.2 2.9 8.6 4.2 8.3 3.7 9.8 5.8 4.6 6.7 6.0 5.5 4.0 2.0 8.5 2.1 3.8 3.9 2.9 6.1 13.3 9.5 7.2 10.8 11.2 5.7 10.3 13.3 7.4 10.9 7.1 0.9 10.0 4.5 26.6 9.8 23.8 60.3 25.8 26.4 7.2 47.1 25.9 25.2 0.6 27.8 11.6 14.4 12.9 5.5 5.5 5.4 7.9 7.0 5.9 5.1 5.1 5.7 4.5 4.1 5.9 6.4 9.8 6.4 4.5 15.3 24.9 2.9 6.5 13.4 8.0 49.9 4.4 3.7 33.0 7.2 5.8 11.0 56.3 12.3 23.8 5.4 0.0 8.5 3.7 3.2 9.7 12.9 16.9 13.7 23.5 5.3 2.1 10.8 4.6 3.6 1.3 14.0 9.7 5.7 7.0 40.4 29.1 7.5 10.2 8.3 6.2 3.7 27.1 6.0 12.4 15.0 16.0 13.0 59.8 31.7 23.5 6.4 7.4 17.7 19.1 5.5 4.3 4.0 8.0 78.3 13.1 11.6 9.5 36.5 28.0 4.6 1.0 1.9 22.9 14.0 9.7 6.3 F7 ENSG00000057593 "Coagulation factor VII" P08709 13 113105788-113120685 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 102 "liver: 160.2" "Cell type enriched" "Detected in some" 18 "Hepatocytes: 149.3" "Cancer enriched" "Detected in some" 17 "liver cancer: 41.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "CACO-2: 11.5;Hep G2: 7.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA004826 Approved Mitochondria "Secreted to blood" NA NA 351000000 1300000000 "Cluster 62: Liver - Hemostasis" "Cluster 39: CACO-2 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" Mitochondria "HPA004826: AB_10602805" "unprognostic (2.06e-1)" "unprognostic (2.55e-1)" "unprognostic (1.03e-1)" "unprognostic (1.34e-1)" "unprognostic (3.27e-1)" "unprognostic (1.91e-1)" "unprognostic (1.50e-3)" "unprognostic (3.81e-1)" "unprognostic (4.36e-3)" "unprognostic (1.16e-1)" "unprognostic (4.19e-3)" "unprognostic (1.15e-1)" "unprognostic (1.35e-3)" "unprognostic (3.36e-3)" "unprognostic (1.09e-1)" "unprognostic (2.86e-1)" "unprognostic (1.47e-1)" 0.2 0.0 0.4 0.1 0.3 0.0 0.2 0.5 0.7 1.1 0.2 0.1 0.5 0.1 0.6 0.1 0.5 0.0 0.2 0.3 0.7 0.4 160.2 0.1 0.0 0.3 0.5 0.4 0.1 0.2 0.4 0.1 0.3 0.4 0.0 0.2 0.3 0.0 0.0 0.4 0.8 0.0 0.2 0.1 0.1 1.5 0.6 0.0 0.1 0.0 0.0 0.1 0.5 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 11.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.5 0.7 0.3 0.7 0.3 0.5 0.3 0.2 0.6 0.3 0.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.6 0.3 0.5 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.4 0.0 8.0 0.3 0.2 0.0 0.4 0.0 0.2 0.0 0.3 2.2 149.3 0.1 0.0 0.5 0.4 0.0 2.8 0.7 0.2 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.0 1.1 0.3 0.0 0.2 0.0 0.5 0.1 3.2 4.1 0.0 0.1 0.1 0.2 0.1 0.3 0.0 FAM136A FLJ14668 ENSG00000035141 "Family with sequence similarity 136 member A" Q96C01 2 70295975-70302090 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030103, HPA030104" Enhanced Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 55: Plasma cells - Humoral immune response" Mitochondria "HPA030103: AB_10600194, HPA030104: AB_10600534" "unprognostic (2.81e-1)" "unprognostic (5.76e-2)" "unprognostic (9.16e-2)" "unprognostic (3.69e-2)" "unprognostic (5.53e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (2.66e-4)" "unprognostic (1.14e-1)" "unprognostic (1.12e-2)" "unprognostic (1.28e-2)" "unprognostic (5.91e-2)" "unprognostic (2.09e-1)" "prognostic unfavorable (1.33e-6)" "unprognostic (4.95e-3)" "unprognostic (3.03e-1)" "unprognostic (4.03e-1)" "unprognostic (2.00e-3)" 10.7 12.2 16.0 17.8 16.4 20.4 16.8 16.4 19.4 15.2 16.1 25.9 26.1 10.0 14.6 19.2 14.3 9.7 21.5 16.0 17.8 20.1 32.5 10.5 17.5 17.0 17.0 10.6 31.4 20.6 10.3 18.0 17.9 15.8 27.1 16.4 27.1 14.1 24.5 14.7 21.6 14.0 15.8 13.6 19.6 8.9 17.9 17.7 20.6 22.2 21.4 17.8 10.5 15.5 94.8 83.4 51.5 72.4 26.5 39.1 78.4 50.2 47.7 67.8 46.8 222.0 53.3 64.9 44.5 43.6 58.9 42.5 106.8 40.0 69.2 67.1 121.3 99.7 62.1 138.8 38.1 166.5 62.7 27.0 27.3 63.9 54.0 36.3 73.8 93.0 161.1 51.0 51.0 138.0 107.6 143.9 129.2 127.7 88.7 71.2 96.2 107.1 104.9 65.4 119.7 52.3 37.7 90.6 76.1 47.3 37.6 47.9 44.9 28.9 85.1 44.7 96.2 42.3 70.0 75.2 72.0 93.2 50.1 35.8 27.9 21.0 21.3 39.8 31.9 37.0 23.6 25.9 37.8 33.2 27.3 27.6 2.6 53.4 27.9 24.8 20.5 29.6 16.0 16.4 16.4 19.4 16.0 17.8 17.0 17.0 17.9 15.8 17.9 15.5 16.7 41.7 31.6 8.8 49.5 28.0 35.4 41.3 35.3 26.3 46.6 46.1 54.7 11.5 38.9 33.1 25.0 89.5 46.0 52.3 70.5 71.8 1.3 39.3 28.3 20.1 32.9 50.5 8.6 99.1 107.5 31.9 40.8 47.1 27.9 46.1 18.9 59.3 69.8 8.4 9.4 61.2 44.7 22.4 29.2 3.6 13.4 31.9 28.4 3.7 42.0 29.1 49.4 6.0 3.6 95.0 58.1 18.4 88.6 54.8 69.7 73.5 31.8 26.7 13.1 19.8 32.5 14.0 53.8 49.8 41.9 29.6 36.8 49.2 66.7 45.7 FAM160A2 "C11orf56, DKFZP566M1046, FHIP, FLJ22665, KIAA1759" ENSG00000051009 "Family with sequence similarity 160 member A2" Q8N612 11 6211345-6234711 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 76.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055994, HPA063987" Approved Approved Mitochondria NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA055994: AB_2682999, HPA063987: AB_2685166" "unprognostic (1.40e-1)" "unprognostic (1.58e-1)" "unprognostic (3.44e-2)" "unprognostic (9.59e-3)" "unprognostic (2.20e-2)" "unprognostic (1.51e-1)" "unprognostic (4.16e-2)" "unprognostic (2.64e-1)" "unprognostic (2.19e-1)" "unprognostic (5.02e-2)" "unprognostic (2.16e-1)" "unprognostic (8.04e-2)" "unprognostic (6.65e-2)" "unprognostic (1.93e-1)" "unprognostic (1.64e-1)" "unprognostic (9.58e-2)" "unprognostic (1.85e-1)" 16.5 14.5 6.2 14.2 6.5 42.3 18.1 6.8 7.2 20.1 9.5 29.8 34.1 21.6 9.5 13.2 20.2 17.8 12.4 6.4 3.8 13.8 20.8 16.0 13.3 4.0 4.4 21.3 24.7 16.3 14.9 12.1 3.5 15.7 27.7 9.6 18.6 14.7 14.0 23.5 33.8 15.8 2.9 14.2 18.9 27.2 4.4 11.3 22.7 10.5 8.9 16.5 16.5 4.4 13.5 13.1 9.0 13.4 11.9 12.8 19.5 7.6 9.1 11.1 10.6 11.2 24.4 10.5 8.2 8.9 18.3 17.4 9.2 13.8 6.7 11.6 13.1 3.6 24.1 6.0 9.8 8.9 11.6 11.7 17.0 10.0 17.7 14.5 11.4 16.2 11.5 12.7 7.0 10.7 8.5 17.0 13.4 17.5 12.2 9.3 4.7 8.6 10.4 9.6 12.0 7.9 10.9 12.7 6.9 9.3 8.7 12.4 9.8 13.6 10.4 20.4 8.1 17.0 15.7 8.1 15.0 7.0 12.3 1.3 3.1 3.4 3.0 1.3 1.8 1.3 1.2 2.2 2.0 1.3 0.9 1.6 3.3 1.1 1.0 0.6 0.2 2.0 6.2 6.5 6.8 7.2 6.4 3.8 4.0 4.4 3.5 2.9 4.4 4.4 19.0 19.2 16.2 28.1 10.1 12.5 11.1 12.5 10.8 12.6 17.8 12.3 4.5 14.3 12.2 12.9 16.7 13.5 15.9 76.8 7.9 11.4 24.2 15.6 10.1 15.2 25.0 18.5 21.3 11.3 10.1 12.9 33.6 11.2 7.0 27.6 9.3 23.7 9.6 6.7 15.8 37.9 16.2 17.6 28.5 6.5 9.9 12.3 14.2 11.2 16.9 7.6 37.0 14.1 15.6 17.6 47.8 7.5 8.3 10.8 65.0 8.8 18.6 24.4 13.1 10.6 11.6 38.5 21.7 8.5 14.9 11.5 14.7 21.9 39.5 10.4 FAM162A "C3orf28, E2IG5" ENSG00000114023 "Family with sequence similarity 162 member A" Q96A26 3 122384176-122412334 "Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 625.3;Distal tubular cells: 540.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035856, HPA075611" Approved Supported Mitochondria NA NA 19000 "Cluster 27: Non-specific - Gene expression" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA035856: AB_10611965, HPA075611: " "unprognostic (1.17e-2)" "unprognostic (1.42e-1)" "unprognostic (5.64e-2)" "unprognostic (1.10e-1)" "unprognostic (3.99e-1)" "unprognostic (7.84e-2)" "unprognostic (1.01e-1)" "unprognostic (1.15e-1)" "unprognostic (5.91e-3)" "unprognostic (8.74e-2)" "unprognostic (1.95e-2)" "unprognostic (7.91e-3)" "unprognostic (4.75e-2)" "unprognostic (2.69e-1)" "unprognostic (1.06e-1)" "unprognostic (4.10e-2)" "prognostic favorable (3.93e-4)" 49.0 105.7 54.8 31.3 60.2 39.9 43.9 57.3 82.2 84.5 57.1 145.9 56.1 49.5 59.4 207.6 49.7 46.2 174.2 57.1 58.5 107.6 200.3 32.0 32.9 55.9 57.2 84.3 133.9 116.6 51.0 17.6 55.6 74.6 149.0 83.5 59.8 49.2 141.0 89.8 56.3 44.6 56.6 31.7 93.2 43.6 58.8 34.7 44.1 142.6 42.7 76.9 131.5 55.6 132.0 27.7 40.4 75.6 72.1 66.4 20.7 52.9 46.8 49.0 123.9 69.4 58.7 142.1 89.2 18.2 40.3 89.8 73.5 128.1 130.0 74.0 55.1 115.6 44.0 125.8 47.4 114.0 39.6 77.3 65.5 46.7 97.9 164.3 66.0 137.7 79.2 55.6 71.1 52.0 116.9 137.9 59.5 294.9 144.4 69.5 57.8 186.9 144.3 314.9 60.1 48.1 39.4 92.4 114.3 59.9 57.9 55.7 47.0 48.4 34.6 28.7 55.6 108.8 39.9 144.8 143.3 109.7 22.8 9.9 25.8 75.7 58.3 68.2 86.9 75.3 79.5 74.0 84.6 68.1 85.1 88.6 8.5 50.6 75.9 70.4 80.4 38.8 54.8 60.2 57.3 82.2 57.1 58.5 55.9 57.2 55.6 56.6 58.8 55.6 55.7 28.9 46.0 41.1 68.2 128.1 155.3 625.3 82.0 31.5 80.6 109.5 338.4 84.4 188.6 130.6 47.9 51.4 47.9 477.5 540.0 148.2 102.5 82.0 30.1 49.8 106.9 47.7 33.0 177.6 47.8 78.7 84.6 79.2 85.7 59.3 44.6 280.4 92.7 38.7 30.4 374.3 240.1 66.7 108.9 33.1 134.5 61.2 104.9 7.5 108.9 79.7 45.3 22.1 21.6 141.6 313.2 148.6 61.2 121.4 186.2 466.2 95.5 29.9 105.2 83.2 315.3 146.4 68.3 315.1 132.8 47.2 66.0 121.1 358.4 210.9 FAM167A "C8orf13, DIORA-1" ENSG00000154319 "Family with sequence similarity 167 member A" Q96KS9 8 11421476-11475908 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.1;thyroid gland: 53.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 16.0;Astrocytes: 28.4;Distal tubular cells: 13.7;Early spermatids: 24.8;Enteroendocrine cells: 19.1;Late spermatids: 41.1" "Cancer enhanced" "Detected in many" "thyroid cancer: 16.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Daudi: 57.6;RPMI-8226: 61.5;SH-SY5Y: 44.4;U-698: 44.8;U-87 MG: 36.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023915, HPA030426" Approved Approved Mitochondria NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 68: Epididymis - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Mitochondria "HPA023915: AB_1845768, HPA030426: AB_10601318" "unprognostic (8.51e-3)" "unprognostic (2.43e-1)" "unprognostic (1.25e-3)" "prognostic unfavorable (5.96e-4)" "unprognostic (3.08e-2)" "unprognostic (4.62e-3)" "unprognostic (1.79e-1)" "unprognostic (1.45e-1)" "unprognostic (1.51e-1)" "unprognostic (1.39e-1)" "unprognostic (4.06e-2)" "unprognostic (7.17e-2)" "unprognostic (1.77e-2)" "unprognostic (7.13e-2)" "unprognostic (1.56e-1)" "unprognostic (4.30e-2)" "unprognostic (2.21e-2)" 0.6 0.8 25.8 1.2 25.1 0.7 1.3 23.9 25.3 0.8 17.0 0.7 0.3 0.1 0.5 0.9 1.3 1.0 0.2 26.6 26.7 6.4 0.3 10.2 2.4 29.8 27.6 0.0 2.1 1.7 17.4 0.9 27.9 1.5 0.7 5.2 2.6 4.6 0.0 11.8 1.3 0.0 26.6 1.2 2.0 3.8 31.1 3.0 53.2 0.1 3.0 0.3 1.6 25.1 4.8 3.0 6.1 0.6 0.4 2.5 0.2 16.8 16.0 10.1 4.4 0.2 1.5 57.6 0.9 18.3 4.7 1.6 0.1 4.0 11.9 24.8 0.8 0.0 0.1 0.0 20.8 0.0 0.1 2.9 2.6 5.3 32.2 32.3 0.0 0.0 0.2 2.2 6.0 1.8 0.1 0.0 1.6 0.1 0.1 0.3 0.0 61.5 5.1 0.5 26.3 44.4 0.8 4.7 2.2 0.8 1.8 0.1 28.5 1.0 1.6 25.8 0.2 17.7 14.0 44.8 36.3 0.1 1.6 0.0 0.0 0.0 0.0 0.5 0.0 1.2 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.3 0.5 0.4 0.0 0.0 25.8 25.1 23.9 25.3 26.6 26.7 29.8 27.6 27.9 26.6 31.1 25.1 0.0 16.0 1.8 28.4 5.4 5.9 0.6 0.5 0.0 0.1 1.2 1.3 0.7 1.5 0.5 5.5 10.4 0.0 1.1 0.2 13.7 2.1 24.8 2.1 0.2 0.2 19.1 0.0 0.6 1.8 0.0 0.3 2.6 0.9 0.0 0.0 0.0 0.0 0.1 0.0 1.4 1.3 0.0 0.3 0.3 41.1 0.3 0.3 0.0 3.7 0.3 1.7 0.0 0.0 1.3 1.1 2.4 0.4 0.9 0.8 0.1 0.2 1.9 1.8 0.0 0.3 0.2 3.9 2.2 0.0 3.4 0.0 1.0 0.1 0.1 0.2 FASTKD2 KIAA0971 ENSG00000118246 "FAST kinase domains 2" Q9NYY8 2 206765357-206796189 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ribosome biogenesis" "RNA-binding, rRNA-binding" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067191 Supported Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA067191: AB_2685801" "unprognostic (1.19e-1)" "unprognostic (2.45e-1)" "unprognostic (3.50e-3)" "unprognostic (1.36e-3)" "unprognostic (7.40e-2)" "unprognostic (2.69e-3)" "prognostic unfavorable (8.29e-4)" "unprognostic (1.69e-2)" "unprognostic (2.98e-2)" "unprognostic (1.11e-1)" "unprognostic (1.38e-3)" "unprognostic (1.48e-1)" "unprognostic (6.32e-2)" "unprognostic (4.87e-2)" "unprognostic (7.18e-2)" "unprognostic (1.03e-3)" "unprognostic (3.57e-2)" 14.4 14.0 5.2 12.4 5.9 11.4 17.3 4.8 6.2 12.8 7.5 15.0 14.9 15.8 8.8 15.9 12.9 11.5 24.9 5.7 5.3 17.4 27.2 11.8 14.3 5.8 4.5 15.7 11.6 18.4 6.9 13.0 6.5 13.3 17.0 11.2 11.2 11.1 31.5 11.8 12.5 15.7 4.4 11.2 13.3 12.0 4.9 13.1 17.8 36.6 17.2 20.4 9.6 4.8 30.2 27.0 24.7 28.1 27.2 32.7 46.2 34.3 29.0 57.3 32.4 48.3 32.0 37.4 37.5 35.5 66.7 40.0 30.7 47.4 50.4 11.7 19.8 29.4 25.6 46.6 33.1 64.3 26.5 35.2 48.8 43.8 47.2 29.1 39.3 27.2 56.4 18.6 42.8 25.3 27.3 27.4 44.0 28.2 51.2 23.7 38.1 38.8 39.4 49.7 36.0 22.9 26.6 44.7 41.3 36.8 20.9 33.4 30.8 35.0 31.5 24.4 36.3 18.5 32.9 48.0 40.6 29.2 29.5 9.6 21.4 5.2 19.2 21.4 21.5 20.1 21.3 20.2 31.0 17.3 28.0 25.2 1.4 31.2 16.5 14.6 18.7 20.5 5.2 5.9 4.8 6.2 5.7 5.3 5.8 4.5 6.5 4.4 4.9 4.8 17.8 28.9 11.4 19.6 20.3 23.7 33.7 28.8 32.5 18.9 11.1 12.2 23.2 7.2 22.8 12.9 22.9 28.2 15.1 6.7 9.8 19.2 30.9 14.5 23.1 14.6 7.3 11.6 41.9 15.1 22.4 21.2 27.5 14.9 5.1 17.5 9.3 17.6 14.8 6.7 40.3 10.5 12.2 7.9 9.4 8.0 9.6 10.8 5.4 25.3 12.9 9.3 8.2 26.2 23.2 12.1 8.2 13.9 20.0 13.7 8.8 12.7 15.9 22.8 13.1 19.3 17.4 37.5 12.8 24.5 21.5 25.7 18.4 18.6 13.1 22.6 FBP1 FBP ENSG00000165140 "Fructose-bisphosphatase 1" P09467 9 94603133-94640249 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Gluconeogenesis" "Allosteric enzyme, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 324.4;kidney: 297.8;liver: 893.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 500.4;Macrophages: 238.6;Proximal enterocytes: 1095.0;Proximal tubular cells: 864.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 404.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HaCaT: 75.2;MCF7: 243.4;OE19: 54.5;RT4: 157.0;U-698: 170.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA005857, HPA012513, CAB033869" Enhanced Approved Mitochondria NA NA 21000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "CAB033869: AB_1121520, HPA005857: AB_1848445, HPA012513: AB_1848446" "unprognostic (4.95e-2)" "unprognostic (1.40e-2)" "unprognostic (1.40e-1)" "prognostic favorable (5.16e-4)" "unprognostic (1.13e-2)" "unprognostic (1.37e-1)" "prognostic favorable (1.79e-4)" "unprognostic (6.94e-3)" "unprognostic (4.52e-2)" "unprognostic (7.79e-2)" "unprognostic (7.59e-2)" "unprognostic (1.12e-1)" "prognostic favorable (6.86e-7)" "unprognostic (6.91e-2)" "unprognostic (3.22e-2)" "unprognostic (1.07e-1)" "prognostic favorable (1.64e-5)" 13.7 27.4 1.6 12.7 1.8 15.0 41.4 1.8 5.7 19.9 2.6 29.8 324.4 3.6 15.8 2.7 7.1 34.4 2.9 1.5 2.2 297.8 893.2 165.9 6.8 3.6 2.6 1.1 41.4 107.9 8.6 3.0 2.9 25.8 30.5 0.7 53.2 28.9 1.3 8.1 258.1 8.8 2.6 12.2 85.6 2.5 3.2 2.2 16.8 0.9 7.8 70.8 6.7 3.8 0.5 0.1 0.3 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.1 0.6 3.8 0.0 0.3 0.8 0.1 75.2 0.1 0.0 0.1 0.0 0.3 0.6 2.9 1.3 0.0 1.5 18.8 0.0 0.1 0.0 0.0 0.0 2.0 0.0 0.2 0.3 0.2 243.4 0.1 4.4 1.1 54.5 9.5 0.0 0.9 1.9 0.0 157.0 0.7 5.6 0.6 44.5 0.0 0.9 26.7 7.7 0.2 0.1 1.0 0.8 0.0 0.3 1.1 170.4 0.0 1.4 0.1 63.3 68.4 404.3 7.9 162.3 11.7 3.0 4.6 4.6 90.1 3.2 16.2 8.3 12.1 15.4 90.7 32.1 2.3 33.1 1.6 1.8 1.8 5.7 1.5 2.2 3.6 2.6 2.9 2.6 3.2 3.8 2.8 76.9 182.8 0.0 10.3 0.8 8.9 0.7 0.0 0.1 62.4 24.3 0.7 102.9 41.0 62.5 0.0 11.1 14.8 26.1 111.6 21.5 0.1 4.0 0.4 4.8 31.9 24.4 0.9 62.7 1.7 5.4 102.4 5.2 47.4 16.0 12.1 500.4 177.6 0.0 0.8 61.4 0.0 79.9 32.1 1.5 1.5 238.6 12.4 1.9 20.1 2.6 8.2 0.5 0.3 24.0 77.6 4.1 18.3 11.9 1095.0 864.1 9.1 0.2 6.6 0.6 2.0 0.6 1.3 0.8 1.0 10.1 12.1 0.5 90.4 68.1 FBXL12 "Fbl12, FLJ20188" ENSG00000127452 "F-box and leucine rich repeat protein 12" Q9NXK8 19 9810267-9827816 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 63.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002843 Approved Approved Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 50: Non-specific - Ribosome" "Cluster 24: NB-4 - Immune response" "Cluster 33: Fibroblasts - ECM organization" Mitochondria "HPA002843: AB_2666679" "unprognostic (7.65e-2)" "unprognostic (5.88e-2)" "unprognostic (7.72e-2)" "unprognostic (3.82e-2)" "unprognostic (8.21e-2)" "prognostic favorable (3.21e-4)" "prognostic unfavorable (1.41e-4)" "unprognostic (6.45e-2)" "prognostic unfavorable (4.96e-4)" "unprognostic (1.38e-3)" "unprognostic (1.49e-2)" "unprognostic (4.07e-3)" "unprognostic (9.28e-3)" "unprognostic (1.41e-1)" "unprognostic (1.36e-1)" "unprognostic (2.61e-1)" "unprognostic (4.77e-3)" 20.0 15.0 8.9 10.4 9.6 27.1 19.1 12.0 10.4 21.5 9.5 22.5 14.9 23.5 10.8 17.2 22.6 9.0 17.0 8.7 9.0 19.4 22.4 17.3 12.8 10.5 8.8 23.9 14.6 7.1 17.5 15.1 10.2 19.5 10.5 6.4 13.5 10.7 19.0 16.6 21.0 11.1 8.0 18.2 17.3 13.2 9.9 44.0 17.6 9.4 8.9 23.6 18.2 10.9 18.8 9.3 21.1 20.6 23.5 20.8 24.1 19.9 20.1 21.2 24.9 28.9 12.1 17.5 31.2 20.1 16.4 17.7 16.0 17.6 16.8 17.7 30.9 33.9 21.1 28.8 30.2 24.8 20.1 29.9 11.5 20.4 18.0 15.6 15.1 44.6 26.2 35.6 11.2 14.9 36.3 76.3 24.3 11.4 17.2 21.5 15.7 31.7 15.3 25.2 13.1 17.9 14.7 10.8 23.4 19.5 15.0 29.1 18.1 29.1 14.1 39.3 20.0 47.7 20.1 27.6 12.3 22.2 14.1 33.5 18.4 36.3 19.0 15.9 21.6 16.7 18.4 21.7 20.6 24.1 21.4 17.0 14.3 31.1 15.3 21.8 22.0 15.2 8.9 9.6 12.0 10.4 8.7 9.0 10.5 8.8 10.2 8.0 9.9 10.9 18.5 6.4 9.2 12.7 15.5 7.4 15.8 16.5 18.8 7.3 14.3 15.9 26.8 15.7 10.8 12.9 4.2 42.1 15.4 26.8 5.9 11.7 2.2 9.6 16.4 15.6 12.6 7.8 15.3 9.9 30.3 24.1 15.3 9.9 3.8 14.2 16.4 7.3 17.2 8.4 14.2 17.0 12.2 9.0 10.0 2.8 26.4 11.0 10.6 8.4 17.7 8.4 13.4 12.5 13.0 9.3 23.4 21.8 8.4 13.5 36.8 10.0 9.3 11.9 13.1 13.7 23.0 24.8 20.8 15.3 11.1 63.3 13.3 18.1 19.7 19.3 FBXO21 "FBX21, KIAA0875" ENSG00000135108 "F-box protein 21" O94952 12 117141991-117190471 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "fallopian tube: 128.9" "Cell type enhanced" "Detected in all" "Peritubular cells: 222.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062411, HPA071452" Approved Approved Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 68: Epididymis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 44: Endometrium - Transcription" Mitochondria "HPA062411: AB_2684755, HPA071452: AB_2686398" "unprognostic (6.38e-2)" "unprognostic (4.43e-2)" "unprognostic (2.58e-2)" "unprognostic (9.00e-3)" "unprognostic (1.57e-1)" "unprognostic (8.89e-2)" "unprognostic (1.84e-1)" "unprognostic (1.37e-1)" "unprognostic (8.99e-2)" "unprognostic (7.01e-3)" "unprognostic (1.28e-2)" "unprognostic (9.44e-2)" "prognostic favorable (2.05e-8)" "unprognostic (1.69e-2)" "unprognostic (1.17e-1)" "unprognostic (2.01e-1)" "unprognostic (7.29e-2)" 12.2 40.9 21.7 10.7 23.0 8.5 17.5 22.2 24.7 18.5 25.7 15.6 16.5 25.0 110.8 15.4 128.9 17.0 31.1 27.2 29.7 53.7 27.5 17.5 13.7 17.5 18.7 60.3 30.7 24.8 20.2 19.5 17.2 26.5 14.6 24.3 16.5 29.3 23.8 16.9 14.3 19.5 20.4 15.2 18.7 42.2 30.2 13.7 28.3 28.5 14.1 16.2 13.8 23.5 20.3 47.3 29.2 16.2 23.5 24.4 33.4 26.6 28.6 24.3 19.7 30.8 14.0 26.5 25.7 27.3 18.2 27.0 34.7 26.6 29.1 15.0 31.2 1.3 24.9 25.0 21.3 8.7 9.0 24.1 25.1 19.5 31.0 39.7 34.4 23.0 10.7 8.6 21.2 33.0 25.0 6.3 43.7 30.9 30.6 29.3 42.5 27.8 24.4 47.7 57.6 34.9 66.4 17.3 14.5 23.3 40.6 3.5 26.8 16.1 20.7 19.1 17.4 15.0 16.6 34.4 23.5 13.5 23.1 1.2 7.0 4.5 11.6 12.2 12.1 10.4 12.0 12.1 9.7 14.3 13.6 12.6 0.6 11.4 12.7 6.6 13.6 8.8 21.7 23.0 22.2 24.7 27.2 29.7 17.5 18.7 17.2 20.4 30.2 23.5 28.5 32.1 35.4 44.1 44.0 37.2 49.1 29.5 40.5 44.3 32.3 26.7 65.4 42.9 39.6 51.5 41.7 58.3 26.3 16.4 45.0 62.5 37.2 108.6 38.3 46.2 39.0 12.0 50.7 50.5 38.0 44.3 24.5 113.1 3.8 57.0 60.0 38.9 15.6 74.0 51.4 23.7 54.9 22.3 17.2 60.4 99.7 17.3 23.2 23.4 18.4 54.1 16.5 41.7 67.5 36.9 16.4 222.3 23.4 48.8 19.0 95.4 29.9 34.1 105.2 35.3 40.6 21.6 43.9 33.9 45.3 65.5 34.1 44.2 27.2 38.3 FBXW5 "DKFZP434B205, Fbw5, MGC20962" ENSG00000159069 "F-box and WD repeat domain containing 5" Q969U6 9 136940435-136944738 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 251.8" "Cell type enhanced" "Detected in all" "Early spermatids: 581.9;Late spermatids: 1900.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046615 Approved Approved Mitochondria No No "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "HPA046615: AB_10965648" "unprognostic (1.11e-1)" "unprognostic (1.10e-2)" "unprognostic (1.56e-2)" "prognostic favorable (1.02e-4)" "unprognostic (4.26e-2)" "unprognostic (1.29e-1)" "unprognostic (2.22e-2)" "unprognostic (7.16e-3)" "unprognostic (2.64e-2)" "unprognostic (7.05e-2)" "unprognostic (3.51e-3)" "unprognostic (3.23e-2)" "prognostic favorable (4.74e-4)" "unprognostic (1.73e-2)" "unprognostic (3.64e-1)" "unprognostic (2.32e-1)" "unprognostic (2.13e-1)" 54.7 58.1 27.6 23.3 23.0 28.7 47.4 23.4 32.4 36.2 23.4 73.9 42.9 44.1 9.4 70.8 33.9 17.7 117.1 34.7 23.5 54.3 132.4 37.5 22.1 27.0 27.2 29.1 75.7 19.0 41.1 15.5 28.3 56.3 13.4 3.9 54.8 26.9 188.7 42.6 59.3 17.2 24.3 47.6 65.0 251.8 33.0 24.7 42.5 66.0 17.6 59.4 41.5 23.7 39.2 65.5 14.9 36.7 36.6 23.6 85.7 40.6 27.5 27.7 15.3 42.9 48.8 27.0 46.0 42.0 21.5 48.0 13.6 35.3 4.6 35.4 47.2 22.9 88.8 46.8 40.0 34.2 55.2 26.9 31.0 25.4 21.1 21.9 28.9 19.5 46.0 42.7 21.3 98.3 26.2 36.4 26.7 48.1 70.6 28.7 22.5 46.3 24.5 37.9 30.9 30.0 49.0 52.8 54.4 5.7 60.3 52.4 55.8 39.5 35.1 75.1 35.1 33.6 45.1 17.0 55.0 29.7 30.5 62.8 62.1 88.0 97.7 74.3 75.3 39.2 73.9 83.3 59.6 31.1 32.0 53.7 32.9 55.4 61.2 98.8 96.8 72.8 27.6 23.0 23.4 32.4 34.7 23.5 27.0 27.2 28.3 24.3 33.0 23.7 61.3 19.2 45.4 13.1 40.7 28.7 44.5 129.0 26.7 29.9 50.1 48.8 86.9 50.1 72.8 23.9 16.7 68.3 108.0 336.5 74.3 111.7 581.9 29.1 27.5 53.6 67.3 36.8 15.9 148.1 132.9 38.9 98.4 38.6 28.6 116.2 46.1 113.3 88.0 60.6 15.3 153.7 65.1 62.6 49.3 1900.7 51.6 69.2 69.4 8.4 124.9 59.1 83.4 11.1 17.1 132.5 238.0 71.1 59.4 84.6 420.9 134.1 43.5 37.3 59.2 33.5 59.0 224.3 47.4 47.1 35.9 101.4 66.6 49.4 127.6 70.0 FDX1 "ADX, FDX" ENSG00000137714 "Ferredoxin 1" P10109 11 110429948-110464884 "Predicted intracellular proteins" "Cholesterol metabolism, Electron transport, Lipid metabolism, Steroid metabolism, Steroidogenesis, Sterol metabolism, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "adrenal gland: 313.7" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 1139.6;Theca cells: 745.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 71.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041630, HPA062087" Enhanced Enhanced Mitochondria NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Mitochondria "HPA041630: AB_10793970, HPA062087: AB_2630366" "unprognostic (1.66e-1)" "unprognostic (1.68e-2)" "unprognostic (5.29e-3)" "unprognostic (4.67e-2)" "unprognostic (2.39e-1)" "unprognostic (4.32e-3)" "unprognostic (1.23e-2)" "unprognostic (2.07e-1)" "unprognostic (2.19e-2)" "unprognostic (4.12e-1)" "unprognostic (3.10e-2)" "unprognostic (5.48e-2)" "prognostic favorable (3.58e-7)" "prognostic favorable (2.53e-4)" "unprognostic (1.10e-1)" "unprognostic (1.94e-1)" "unprognostic (2.80e-1)" 9.0 313.7 6.9 6.8 7.5 12.1 8.5 7.5 8.6 7.4 8.7 12.9 22.0 6.2 8.2 9.3 5.9 9.1 16.3 6.8 7.6 29.6 44.3 10.8 7.9 7.3 7.8 5.4 13.4 9.3 6.1 17.7 7.6 8.2 10.7 5.3 8.6 26.3 20.6 6.2 18.4 6.1 7.5 6.7 13.5 7.6 7.9 12.0 20.3 18.5 7.5 10.5 5.5 8.8 10.2 7.0 10.6 11.6 10.1 17.8 23.5 9.2 11.2 8.0 13.5 24.1 16.7 23.8 26.4 11.9 14.2 11.8 12.4 13.9 10.8 22.9 15.8 12.0 12.0 14.8 17.7 12.7 18.8 31.3 11.4 7.3 17.1 13.8 16.5 16.2 12.2 34.4 17.3 11.3 18.2 28.3 9.5 19.3 13.1 26.4 10.1 22.1 17.4 18.1 14.4 7.4 17.5 19.7 12.5 12.3 11.7 8.7 9.8 8.0 9.8 9.8 9.9 7.7 6.4 71.7 6.0 25.5 10.5 1.8 4.5 2.8 3.8 3.3 4.1 9.7 5.2 5.4 5.2 7.5 6.2 4.4 0.5 3.4 4.6 4.0 7.4 2.6 6.9 7.5 7.5 8.6 6.8 7.6 7.3 7.8 7.6 7.5 7.9 8.8 53.2 19.2 38.1 15.0 68.6 68.3 104.3 45.4 42.7 33.0 40.3 37.0 57.1 102.9 28.3 80.9 8.4 174.3 65.7 109.5 244.6 71.4 53.4 49.6 35.6 36.7 47.9 28.8 22.6 144.8 169.4 48.1 61.2 42.0 45.7 36.3 45.0 192.7 113.3 42.1 25.8 56.2 34.6 58.4 68.3 11.0 46.9 77.3 69.4 15.0 57.3 42.3 50.4 22.1 19.6 78.5 76.5 45.5 102.7 114.2 183.9 338.7 18.6 17.3 26.3 50.6 43.6 48.0 67.0 75.3 97.5 1139.6 74.0 745.1 96.4 149.6 FDXR "ADR, ADXR" ENSG00000161513 "Ferredoxin reductase" P22570 17 74862497-74873031 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Electron transport, Lipid metabolism, Steroid metabolism, Sterol metabolism, Transport" Oxidoreductase "Deafness, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "adrenal gland: 343.1" "Group enriched" "Detected in many" 7 "Granulosa cells: 329.3;Theca cells: 794.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 89.5;Hep G2: 173.5" "Low region specificity" "Detected in all" "CAB008597, CAB009818, HPA044393, HPA053673" Enhanced Enhanced Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 52: Non-specific - Transcription" Mitochondria "CAB008597: AB_1615557, CAB009818: AB_2102601, HPA044393: AB_2678927, HPA053673: AB_2682225" "unprognostic (2.69e-2)" "unprognostic (1.17e-3)" "unprognostic (7.51e-2)" "prognostic favorable (2.38e-4)" "unprognostic (3.43e-2)" "unprognostic (1.20e-1)" "unprognostic (1.53e-1)" "unprognostic (1.68e-2)" "unprognostic (2.29e-1)" "unprognostic (1.50e-1)" "unprognostic (1.09e-1)" "unprognostic (6.30e-2)" "unprognostic (1.42e-2)" "unprognostic (1.19e-2)" "unprognostic (4.50e-2)" "unprognostic (4.03e-2)" "unprognostic (2.13e-1)" 3.9 343.1 6.9 2.4 8.4 2.2 3.8 7.8 8.1 7.8 8.6 9.7 4.6 6.7 5.1 26.0 12.9 4.1 6.0 6.6 6.7 6.5 14.9 5.3 2.9 7.6 7.9 20.5 12.9 5.9 4.1 3.0 7.5 6.7 3.2 0.5 7.1 4.4 7.7 16.4 5.6 2.3 7.4 33.9 7.6 45.6 7.0 4.7 6.0 1.7 2.5 6.2 10.5 7.5 12.5 65.6 9.6 10.8 6.8 9.1 89.5 14.8 15.9 8.6 17.1 18.3 10.8 29.6 2.6 6.2 4.8 24.9 6.9 18.4 2.5 27.9 15.2 22.6 10.6 173.5 19.0 5.0 75.1 29.2 20.3 9.1 3.1 7.0 43.9 10.9 36.1 4.8 13.4 53.4 19.7 10.6 5.5 11.8 14.5 10.6 16.4 16.2 7.1 21.0 5.2 12.1 10.0 21.7 11.2 10.9 47.4 4.7 20.5 5.9 51.9 9.4 7.4 12.7 2.3 6.5 16.1 7.7 20.6 1.7 6.0 5.0 5.6 4.5 5.0 4.8 5.1 6.8 7.3 2.4 4.4 5.4 2.0 10.3 3.4 1.4 15.4 5.2 6.9 8.4 7.8 8.1 6.6 6.7 7.6 7.9 7.5 7.4 7.0 7.5 4.0 3.2 3.9 7.5 8.2 9.7 17.8 42.6 17.1 4.9 6.6 8.4 3.8 5.7 23.3 9.2 4.2 53.2 2.8 18.6 5.9 11.1 6.5 28.2 4.3 4.6 7.1 4.0 1.4 7.9 18.9 12.9 13.7 3.5 5.7 329.3 12.5 13.9 23.1 3.3 2.2 13.1 36.7 6.2 2.7 14.9 5.9 4.6 5.4 1.0 3.9 11.4 8.2 3.0 1.3 9.0 16.9 4.5 7.1 5.2 24.9 21.7 73.6 5.1 0.0 6.2 18.3 6.3 6.1 33.7 18.2 46.1 8.6 794.1 20.3 17.4 FGFR1OP2 DKFZp564O1863 ENSG00000111790 "FGFR1 oncogene partner 2" Q9NVK5 12 26938470-26966650 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 249.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038308, HPA038696" Supported Approved Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 6: Erythroid cells - Oxygen transport" Mitochondria "HPA038308: AB_10672524, HPA038696: AB_10675948" "unprognostic (1.68e-1)" "unprognostic (6.49e-2)" "unprognostic (1.95e-1)" "unprognostic (2.34e-1)" "unprognostic (4.01e-2)" "unprognostic (1.19e-1)" "unprognostic (4.37e-3)" "unprognostic (1.72e-1)" "unprognostic (8.17e-2)" "unprognostic (1.31e-1)" "unprognostic (1.11e-1)" "unprognostic (3.41e-2)" "unprognostic (1.55e-2)" "unprognostic (6.82e-2)" "unprognostic (1.40e-1)" "unprognostic (5.33e-2)" "unprognostic (1.36e-2)" 29.4 41.6 29.0 30.6 32.6 61.6 26.3 28.6 48.3 24.9 21.0 23.1 23.1 31.6 29.0 23.1 23.7 28.7 28.5 34.2 28.1 30.9 27.8 25.7 42.4 29.2 28.6 59.5 15.1 19.3 17.8 27.1 29.3 19.9 20.0 30.7 18.2 18.6 23.3 23.5 22.9 26.6 29.8 33.2 20.5 23.0 27.5 36.2 24.1 32.8 30.9 25.2 21.1 44.3 30.3 36.9 30.5 41.1 51.9 37.4 44.2 51.6 60.1 39.1 42.5 57.3 34.4 44.3 24.8 45.9 37.4 31.4 21.3 38.8 55.5 33.6 31.1 75.0 39.4 38.4 61.3 43.5 54.9 27.3 24.8 47.7 61.6 53.3 56.8 39.6 45.3 33.0 46.2 36.3 58.0 103.3 50.4 39.1 59.9 34.6 84.2 37.1 34.8 36.5 9.3 18.5 58.9 21.5 52.1 69.9 38.5 65.3 61.7 51.6 52.0 95.9 48.5 23.1 25.2 93.4 43.2 50.2 42.7 81.1 31.5 40.6 31.6 31.4 28.3 22.3 33.0 30.7 25.2 19.7 29.8 33.3 32.0 25.9 31.3 20.6 61.3 23.7 29.0 32.6 28.6 48.3 34.2 28.1 29.2 28.6 29.3 29.8 27.5 44.3 70.8 38.5 37.2 39.2 97.1 140.3 62.3 30.6 86.0 52.7 45.4 39.6 45.4 24.3 41.2 27.6 77.2 41.5 114.1 19.9 72.4 28.9 17.9 28.9 47.8 70.1 26.9 249.0 79.4 23.1 37.8 86.5 23.0 30.8 59.5 77.9 70.6 30.7 60.6 58.9 30.6 22.0 26.4 64.7 96.2 18.8 105.3 74.6 88.9 47.8 49.6 64.3 83.4 63.8 128.5 29.7 29.0 170.8 138.2 56.7 27.2 70.0 20.8 48.0 46.0 69.6 81.4 32.9 70.1 57.4 119.8 59.5 141.2 42.9 20.0 63.5 FH ENSG00000091483 "Fumarate hydratase" P07954 1 241497603-241519755 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Tricarboxylic acid cycle" Lyase "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 276.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 173.5;Early spermatids: 226.0;Syncytiotrophoblasts: 166.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017785, HPA025770, HPA025948, HPA027341" Enhanced Supported Enhanced Mitochondria NA NA 1800000 "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB017785: , HPA025770: AB_10599603, HPA025948: AB_10602177, HPA027341: AB_10601222" "unprognostic (1.03e-2)" "unprognostic (3.82e-2)" "unprognostic (9.46e-3)" "unprognostic (2.18e-1)" "unprognostic (2.10e-1)" "unprognostic (2.07e-1)" "unprognostic (2.28e-2)" "unprognostic (1.55e-1)" "unprognostic (5.14e-2)" "unprognostic (1.85e-2)" "unprognostic (1.27e-2)" "unprognostic (1.09e-1)" "prognostic favorable (2.76e-7)" "unprognostic (1.05e-1)" "unprognostic (1.05e-1)" "unprognostic (4.41e-2)" "unprognostic (1.24e-2)" 43.4 75.2 30.4 31.0 33.3 31.4 37.3 33.5 42.0 28.9 43.9 66.8 68.2 36.9 26.1 51.1 27.9 23.7 179.0 33.9 33.1 101.8 276.4 26.4 30.0 31.8 31.0 24.9 38.1 95.0 31.1 32.1 32.1 33.5 69.0 58.8 42.0 38.4 213.4 40.3 59.1 42.0 32.4 30.1 53.6 44.4 32.7 31.3 34.6 229.3 40.4 37.5 33.7 33.0 129.2 105.6 97.9 89.0 93.9 110.0 154.9 155.7 121.1 171.6 107.1 152.2 78.0 81.1 100.3 119.9 75.0 178.4 151.7 115.8 148.4 93.5 48.9 76.3 102.2 131.4 84.1 180.2 66.7 80.2 70.7 96.6 108.0 60.2 107.2 175.8 236.3 101.7 126.9 64.3 156.6 120.1 104.5 186.2 223.6 127.4 107.2 365.7 167.4 107.6 125.4 108.4 131.1 153.3 104.0 67.2 117.1 120.9 106.5 76.6 98.9 137.0 264.0 90.3 103.7 97.3 85.7 203.5 112.6 11.9 22.8 4.9 16.1 33.3 21.0 27.2 18.8 15.1 46.7 25.1 22.3 21.1 1.3 18.3 29.1 23.1 23.8 16.7 30.4 33.3 33.5 42.0 33.9 33.1 31.8 31.0 32.1 32.4 32.7 33.0 17.1 38.5 30.2 9.4 25.0 20.0 24.6 69.5 17.1 24.7 19.9 17.5 173.5 35.8 40.0 23.9 14.6 101.6 13.7 44.0 78.2 60.4 226.0 25.4 23.5 18.6 18.0 37.7 12.7 45.0 58.7 25.5 26.5 25.4 19.0 24.9 13.6 80.4 50.7 35.3 14.9 40.6 48.8 18.5 14.4 37.4 23.9 23.9 24.9 8.4 27.9 35.0 10.3 8.0 14.4 29.4 35.7 26.7 41.3 19.0 66.1 86.0 29.2 39.1 39.5 27.7 67.9 84.7 47.1 32.1 18.6 166.1 14.9 48.4 74.2 22.8 FIS1 "CGI-135, H_NH0132A01.6, TTC11" ENSG00000214253 "Fission, mitochondrial 1" Q9Y3D6 7 101239458-101252316 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 891.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA017430 Approved Supported Mitochondria NA NA 140000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA017430: AB_1848608" "unprognostic (1.45e-2)" "unprognostic (8.20e-2)" "unprognostic (4.31e-2)" "unprognostic (1.78e-1)" "unprognostic (1.48e-2)" "unprognostic (1.63e-1)" "unprognostic (7.73e-2)" "unprognostic (6.54e-2)" "unprognostic (5.33e-2)" "unprognostic (2.93e-1)" "unprognostic (1.36e-3)" "unprognostic (3.47e-2)" "prognostic favorable (1.08e-7)" "unprognostic (1.29e-2)" "unprognostic (1.49e-1)" "unprognostic (1.09e-1)" "unprognostic (1.42e-1)" 205.8 227.6 202.4 60.0 231.0 110.2 195.2 234.0 230.7 149.5 194.5 211.0 83.0 168.1 100.5 155.9 166.0 70.9 382.2 198.4 213.5 250.5 294.9 140.4 73.2 238.9 222.7 152.3 208.7 201.1 209.3 75.4 237.8 160.3 69.5 34.8 142.4 90.0 475.6 174.3 137.3 83.7 223.9 163.0 194.4 145.5 217.6 84.0 178.9 284.2 63.8 163.2 141.1 256.0 110.1 124.3 94.7 133.6 103.6 136.6 63.5 118.1 139.0 103.2 88.3 81.7 173.2 107.4 145.7 159.4 98.1 64.0 65.8 184.5 56.8 87.9 101.0 49.8 154.7 100.6 124.5 93.1 75.0 131.9 172.5 73.4 111.5 117.2 185.6 60.3 109.0 142.9 155.0 445.1 145.1 160.4 100.8 221.2 123.0 70.7 53.4 235.8 155.1 107.5 120.6 141.9 57.0 261.5 83.0 81.3 88.0 101.5 159.6 120.6 76.6 127.9 125.3 122.2 98.6 61.6 111.7 103.0 159.0 153.9 137.7 135.9 122.3 141.7 126.4 152.7 115.5 115.9 149.6 152.8 115.0 120.5 104.5 126.3 131.6 123.2 155.6 207.9 202.4 231.0 234.0 230.7 198.4 213.5 238.9 222.7 237.8 223.9 217.6 256.0 301.0 102.5 119.1 16.0 127.5 104.9 158.6 158.4 114.4 48.2 220.5 309.2 349.4 207.3 114.8 229.9 16.7 259.8 120.7 334.5 561.5 263.5 208.5 145.4 120.7 205.8 219.4 423.7 13.6 293.4 309.2 166.7 110.1 126.4 136.3 132.4 182.0 384.9 297.0 35.3 13.2 317.9 128.1 170.9 133.5 730.3 193.9 136.0 218.7 15.0 214.1 281.5 171.9 6.6 83.1 232.2 460.4 179.0 184.8 221.0 603.6 891.2 130.9 59.6 98.6 161.1 233.3 188.0 201.2 192.7 135.7 324.1 127.5 247.4 277.5 192.5 FKBP10 "FKBP6, FKBP65, FLJ20683, FLJ22041, FLJ23833, hFKBP65" ENSG00000141756 "FKBP prolyl isomerase 10" Q96AY3 17 41812680-41823213 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Isomerase, Rotamase" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 79.1;Fibroblasts: 100.0;Sertoli cells: 59.2;Smooth muscle cells: 65.3;Theca cells: 54.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 551.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051171, HPA057021" Enhanced Approved Mitochondria "Intracellular and membrane" NA NA 110000 "Cluster 22: NK-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Mitochondria "HPA051171: AB_2681371, HPA057021: AB_2683312" "unprognostic (8.30e-2)" "prognostic unfavorable (4.16e-4)" "unprognostic (9.05e-2)" "unprognostic (1.71e-2)" "unprognostic (4.77e-2)" "unprognostic (2.95e-2)" "unprognostic (1.14e-2)" "unprognostic (9.98e-2)" "unprognostic (2.21e-2)" "unprognostic (7.57e-2)" "unprognostic (1.14e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.34e-2)" "unprognostic (5.77e-2)" "prognostic unfavorable (3.43e-5)" "prognostic unfavorable (4.99e-4)" 39.4 39.5 20.9 27.1 22.2 0.5 33.5 21.7 26.1 64.0 22.0 29.1 7.6 61.5 16.9 13.9 50.9 46.0 45.6 20.3 22.1 17.7 7.8 37.8 10.9 24.6 21.6 58.4 15.1 48.5 56.7 60.7 22.2 32.6 10.8 6.0 14.7 30.8 7.6 20.4 19.1 55.6 21.9 14.3 18.5 9.0 24.2 4.9 34.9 9.3 4.4 42.2 39.1 21.6 0.7 119.6 110.7 363.3 379.3 441.7 92.0 490.4 497.4 185.6 159.0 62.1 4.8 0.3 6.6 551.9 45.9 0.8 66.7 133.4 77.9 33.0 99.9 48.6 132.1 181.0 411.4 0.0 0.6 476.1 0.5 150.3 115.5 352.6 158.8 0.0 1.9 16.7 157.0 163.2 0.3 0.1 85.4 258.0 38.3 9.9 125.2 15.7 31.7 0.1 26.7 92.1 0.7 349.3 166.0 137.4 54.1 3.1 181.0 219.0 111.5 145.8 76.0 0.8 0.2 0.3 299.7 0.0 213.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 20.9 22.2 21.7 26.1 20.3 22.1 24.6 21.6 22.2 21.9 24.2 21.6 14.9 0.0 4.8 38.2 0.2 8.5 11.5 2.7 1.2 0.6 10.8 13.2 2.3 1.5 1.4 0.0 0.0 6.1 0.2 0.1 0.0 8.7 0.7 3.0 79.1 34.9 0.0 0.0 0.3 4.7 30.8 100.0 1.5 4.6 0.0 32.9 30.4 0.0 4.7 15.2 0.3 1.3 0.0 0.0 9.7 2.9 46.9 1.5 16.0 15.0 0.0 32.0 0.0 17.1 0.1 2.2 0.1 44.8 0.5 8.2 0.0 0.0 0.1 1.1 59.2 35.2 65.3 0.9 7.6 0.5 5.1 11.9 2.1 54.0 0.6 1.6 FMC1 "C7orf55, HSPC268" ENSG00000164898 "Formation of mitochondrial complex V assembly factor 1 homolog" Q96HJ9 7 139339457-139346328 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting duct cells: 84.6;Distal tubular cells: 199.6;Proximal tubular cells: 196.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEK 293: 67.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045663, HPA050553" Approved Approved Mitochondria NA NA "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA045663: AB_2679410, HPA050553: AB_2681173" "unprognostic (3.71e-2)" "unprognostic (1.15e-2)" "unprognostic (3.69e-1)" "unprognostic (3.80e-2)" "unprognostic (8.90e-2)" "unprognostic (9.00e-2)" "unprognostic (4.39e-2)" "prognostic favorable (1.08e-4)" "unprognostic (2.19e-1)" "prognostic favorable (5.63e-6)" "unprognostic (1.04e-3)" "unprognostic (2.39e-2)" "prognostic favorable (2.05e-5)" "unprognostic (1.50e-1)" "unprognostic (3.40e-2)" "unprognostic (4.67e-1)" "unprognostic (3.02e-2)" 8.5 11.5 19.1 2.8 20.1 6.2 8.2 20.1 23.1 6.6 20.0 9.7 7.0 8.1 11.6 5.5 9.3 5.2 28.5 19.3 19.8 16.2 17.7 5.2 5.5 20.0 19.8 11.2 10.3 11.1 12.0 3.3 19.9 11.2 5.1 3.1 12.8 7.7 30.5 5.0 7.0 3.7 19.5 6.4 11.3 5.7 19.6 7.5 10.7 39.0 3.0 8.6 5.8 21.5 5.6 19.5 11.2 11.7 6.0 5.2 4.9 1.8 4.6 13.2 9.8 6.6 7.1 12.6 11.3 5.9 10.5 4.3 11.0 4.8 3.2 6.3 67.5 6.1 19.9 29.3 12.8 5.3 8.8 13.5 9.3 4.4 3.7 4.8 10.8 8.6 12.4 18.9 7.6 39.2 12.8 35.7 11.1 9.9 28.2 7.7 5.5 17.6 11.1 5.0 22.1 14.5 6.3 5.2 8.1 1.8 2.5 4.3 5.1 4.7 4.4 5.6 5.0 6.7 7.2 14.4 12.1 11.7 7.7 13.3 10.3 10.9 11.2 6.7 9.9 25.3 13.7 11.4 12.0 20.5 15.7 11.2 3.3 16.1 7.6 21.4 16.9 6.6 19.1 20.1 20.1 23.1 19.3 19.8 20.0 19.8 19.9 19.5 19.6 21.5 31.3 44.8 47.6 0.0 10.1 0.0 0.0 0.0 0.0 0.0 57.1 57.4 0.0 0.0 19.8 84.6 0.0 63.0 11.9 0.0 199.6 35.4 0.0 67.8 40.1 14.5 0.0 0.0 0.0 35.3 24.2 20.3 0.0 43.9 12.6 27.6 0.0 0.0 39.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.3 0.0 0.0 12.9 0.0 0.0 0.0 0.0 23.6 0.0 0.0 4.1 0.0 0.0 196.2 37.2 0.0 0.0 0.0 20.8 0.0 0.0 0.0 0.0 47.6 9.4 40.9 0.0 0.0 FN3K ENSG00000167363 "Fructosamine 3 kinase" Q9H479 17 82735615-82751196 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 79.8" "Cell type enhanced" "Detected in many" "Distal tubular cells: 90.1;Proximal tubular cells: 167.2;Rod photoreceptor cells: 72.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 34.3;Hep G2: 66.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059151, HPA061358" Supported Approved Mitochondria NA NA 180000 "Cluster 35: Non-specific - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA059151: AB_2683931, HPA061358: AB_2684490" "unprognostic (4.74e-2)" "unprognostic (9.19e-2)" "unprognostic (4.22e-2)" "prognostic favorable (1.10e-4)" "unprognostic (6.10e-2)" "unprognostic (1.39e-1)" "unprognostic (6.45e-2)" "unprognostic (9.86e-2)" "unprognostic (5.08e-2)" "unprognostic (2.61e-1)" "prognostic favorable (2.40e-4)" "unprognostic (6.66e-2)" "prognostic favorable (1.39e-6)" "unprognostic (2.68e-2)" "unprognostic (8.02e-2)" "unprognostic (4.77e-1)" "unprognostic (1.22e-2)" 14.4 47.3 47.4 2.9 64.3 12.0 8.4 64.4 56.6 10.4 36.8 15.5 22.4 9.4 7.0 4.6 12.5 6.9 47.5 46.5 54.3 49.6 48.1 7.8 2.4 63.3 56.8 22.3 18.1 21.9 22.4 5.3 62.7 12.5 9.5 13.8 28.5 12.1 23.5 5.3 14.5 6.6 49.4 4.6 17.4 5.2 55.6 1.0 10.2 10.9 2.3 8.8 7.9 79.8 1.3 16.1 4.4 23.2 6.9 5.7 2.9 2.9 2.2 5.4 2.7 21.0 3.3 0.2 3.9 2.6 4.5 0.6 34.3 2.5 2.0 1.0 2.4 12.5 12.9 66.2 18.8 0.3 10.1 4.9 9.0 2.1 0.0 5.7 10.6 1.0 22.4 0.6 1.1 1.8 0.2 0.2 2.9 7.6 13.0 2.1 0.3 0.1 11.5 4.5 7.0 22.7 5.3 1.2 15.8 3.8 15.4 4.5 2.5 0.4 1.6 5.6 4.3 1.2 0.3 0.1 0.4 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.4 64.3 64.4 56.6 46.5 54.3 63.3 56.8 62.7 49.4 55.6 79.8 3.9 3.2 2.0 8.8 1.9 1.5 3.7 1.5 14.8 41.9 4.5 3.7 5.8 4.3 2.5 31.3 47.9 11.7 2.6 5.7 90.1 3.2 0.2 11.6 3.0 5.2 5.4 49.2 10.2 1.2 2.6 8.6 47.9 25.9 1.3 6.9 4.2 5.4 8.2 32.0 13.0 10.4 6.1 1.0 3.4 0.4 5.3 5.7 12.4 5.6 1.2 36.2 1.0 6.0 17.1 1.7 7.3 3.0 9.1 3.9 28.2 167.2 2.5 72.9 0.0 6.1 9.8 0.8 4.1 12.8 1.8 8.3 3.1 18.6 9.5 3.5 FOCAD "FLJ20375, KIAA1797" ENSG00000188352 Focadhesin Q5VW36 9 20658309-20995955 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "choroid plexus: 154.6" "Cell type enhanced" "Detected in all" "Excitatory neurons: 529.1;Inhibitory neurons: 314.2;Oligodendrocyte precursor cells: 140.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055015 Approved Uncertain Mitochondria NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Mitochondria "HPA055015: AB_2682673" "unprognostic (3.05e-2)" "unprognostic (1.02e-1)" "prognostic favorable (3.25e-4)" "unprognostic (3.69e-3)" "unprognostic (4.14e-2)" "unprognostic (5.35e-2)" "prognostic unfavorable (4.41e-5)" "unprognostic (9.64e-2)" "unprognostic (7.38e-2)" "unprognostic (1.23e-1)" "unprognostic (5.26e-2)" "unprognostic (9.15e-2)" "prognostic favorable (3.09e-8)" "unprognostic (1.90e-1)" "unprognostic (2.33e-1)" "unprognostic (3.99e-2)" "unprognostic (1.41e-2)" 7.3 19.4 15.0 6.1 14.7 5.2 7.7 12.7 21.9 8.5 154.6 9.5 4.5 9.0 11.2 8.9 13.2 5.2 12.5 23.0 20.6 9.5 4.9 8.6 5.3 10.7 8.1 7.4 12.8 12.3 25.1 8.3 10.5 10.5 10.4 7.1 11.9 7.1 11.2 8.5 6.4 9.0 5.2 6.2 8.2 7.7 15.8 14.5 20.4 11.8 6.2 7.3 7.7 17.5 32.8 22.2 23.7 17.8 21.7 24.7 12.5 19.1 30.2 13.3 15.1 14.8 11.0 13.4 9.9 27.4 11.1 11.2 20.8 37.8 23.0 59.8 15.4 10.5 25.3 18.5 11.2 17.5 13.0 22.9 25.5 13.2 21.6 18.5 51.3 11.1 0.3 19.2 22.3 12.6 13.3 33.0 18.7 17.4 22.2 0.1 10.7 9.0 20.6 13.9 15.7 7.9 12.6 21.3 5.2 31.5 13.3 10.2 31.7 0.1 8.7 14.7 17.5 4.7 28.3 15.0 0.0 24.3 8.0 6.8 1.6 4.9 2.9 3.3 3.8 1.5 2.5 2.8 4.0 2.6 2.2 2.7 1.2 2.7 1.9 1.6 2.6 1.7 15.0 14.7 12.7 21.9 23.0 20.6 10.7 8.1 10.5 5.2 15.8 17.5 7.0 9.6 14.7 85.8 5.2 2.9 2.8 4.5 6.8 5.8 5.8 5.1 14.9 4.3 8.6 16.5 4.2 4.7 4.1 7.9 1.9 8.1 16.6 21.2 6.7 6.0 17.5 5.5 529.1 8.6 7.6 8.7 12.8 6.8 5.1 13.9 9.7 4.0 5.1 11.8 314.2 10.1 10.2 4.4 3.5 5.0 5.0 5.3 8.8 74.9 2.8 7.9 2.1 140.8 59.0 8.9 3.4 3.8 10.7 5.8 2.5 4.8 25.0 4.0 6.6 11.2 6.7 13.7 7.5 11.2 3.7 3.3 5.7 7.0 10.4 3.0 FOXRED1 H17 ENSG00000110074 "FAD dependent oxidoreductase domain containing 1" Q96CU9 11 126269055-126278131 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" Oxidoreductase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039620, HPA046192" Uncertain Supported Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 12: Non-specific - Cell cycle regulation" Mitochondria "HPA039620: AB_2676602, HPA046192: AB_2679580" "prognostic unfavorable (7.36e-4)" "unprognostic (4.62e-2)" "unprognostic (2.71e-1)" "unprognostic (3.47e-3)" "unprognostic (1.76e-1)" "unprognostic (1.84e-1)" "unprognostic (9.59e-2)" "unprognostic (1.43e-1)" "unprognostic (8.14e-2)" "unprognostic (1.20e-1)" "unprognostic (1.20e-2)" "unprognostic (1.59e-1)" "prognostic favorable (2.01e-6)" "unprognostic (1.57e-1)" "unprognostic (1.10e-1)" "unprognostic (2.00e-1)" "unprognostic (1.94e-1)" 8.1 13.8 13.6 5.9 14.6 12.1 7.6 15.3 16.6 5.8 17.1 12.0 10.4 6.7 6.4 9.2 7.5 5.6 21.2 15.0 14.7 14.7 37.4 5.3 10.4 15.3 14.3 4.8 7.8 9.7 8.1 7.1 15.3 6.9 12.9 3.7 7.3 6.8 17.8 7.5 8.6 7.9 14.7 11.1 10.9 8.7 15.8 11.5 6.1 29.4 10.6 7.1 6.0 14.8 23.5 26.6 19.5 24.3 14.2 6.8 26.1 11.6 14.9 22.1 22.1 40.0 24.1 38.2 32.3 9.8 28.7 38.5 51.7 31.5 13.8 20.4 14.3 79.7 16.7 48.2 18.8 19.7 16.4 6.3 12.1 14.9 26.5 6.0 24.7 40.2 46.6 20.6 18.7 32.7 23.1 35.3 16.0 61.8 45.2 37.0 34.1 45.2 20.5 11.9 25.0 21.5 23.8 35.7 13.1 12.2 85.9 33.4 9.0 13.1 10.7 23.8 19.4 12.2 19.0 31.9 16.2 66.5 18.7 1.6 10.1 5.9 6.7 13.4 7.0 7.1 5.3 8.9 12.1 6.2 7.4 6.7 2.0 9.9 9.9 16.8 7.6 8.1 13.6 14.6 15.3 16.6 15.0 14.7 15.3 14.3 15.3 14.7 15.8 14.8 6.1 9.6 11.5 19.6 13.5 3.6 6.2 14.9 8.0 24.8 7.3 7.0 21.7 10.0 10.7 3.7 27.1 27.7 12.2 12.6 7.9 13.6 4.2 7.4 8.7 7.6 13.1 14.9 24.7 13.8 24.1 9.8 17.9 7.8 9.5 17.8 10.0 28.2 20.4 13.5 27.1 12.6 8.2 7.1 5.1 7.2 5.6 8.0 8.8 4.7 7.1 18.6 9.2 14.1 16.1 10.7 5.9 11.3 24.4 4.6 8.9 21.0 6.7 32.2 6.6 8.9 9.6 24.5 24.0 11.0 5.7 21.1 8.9 25.0 14.9 4.8 FRMD6 "C14orf31, EX1, MGC17921, willin" ENSG00000139926 "FERM domain containing 6" Q96NE9 14 51489100-51730727 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 160.6;Early spermatids: 219.1;Late spermatids: 473.0;Suprabasal keratinocytes: 137.5;Urothelial cells: 130.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 351.1;fHDF/TERT166: 765.6;U-138 MG: 290.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001297 Uncertain Supported Approved Mitochondria NA NA "Cluster 10: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "HPA001297: AB_1078913" "unprognostic (1.30e-1)" "unprognostic (1.09e-1)" "unprognostic (1.84e-1)" "unprognostic (2.29e-1)" "unprognostic (2.64e-2)" "unprognostic (8.05e-2)" "unprognostic (8.19e-2)" "unprognostic (3.55e-3)" "unprognostic (1.28e-1)" "unprognostic (2.45e-2)" "prognostic unfavorable (2.66e-4)" "unprognostic (3.18e-2)" "prognostic unfavorable (1.28e-4)" "prognostic unfavorable (3.50e-4)" "unprognostic (1.18e-1)" "unprognostic (2.11e-2)" "unprognostic (1.20e-2)" 12.1 13.4 5.2 9.5 5.2 1.2 27.1 12.6 6.7 28.1 8.4 16.0 5.2 53.6 11.3 59.8 13.4 33.0 7.3 6.4 4.5 4.2 10.4 8.6 5.5 5.7 8.1 25.9 5.0 2.4 3.4 14.1 4.9 27.7 10.8 1.5 21.5 30.7 7.4 43.2 7.5 46.8 5.4 12.0 7.2 31.0 5.8 12.6 6.6 6.8 12.7 31.5 30.1 5.6 71.4 14.1 20.1 42.1 40.1 67.6 8.8 351.1 163.2 169.5 146.0 51.9 16.4 1.9 10.6 765.6 47.6 82.8 5.7 113.8 200.3 1.1 8.6 0.3 7.6 2.2 46.8 0.2 4.2 58.8 40.9 152.0 200.5 77.8 52.6 3.7 0.7 24.6 181.8 12.2 7.1 0.2 3.9 0.2 27.4 0.8 79.1 0.7 33.4 113.7 4.1 44.9 27.8 3.9 31.3 37.7 3.0 1.0 242.6 290.7 97.6 73.3 73.5 18.9 17.3 0.2 19.3 0.3 114.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.1 0.0 0.0 0.1 5.2 5.2 12.6 6.7 6.4 4.5 5.7 8.1 4.9 5.4 5.8 5.6 6.9 3.2 1.5 34.6 0.8 111.4 160.6 42.4 41.5 0.4 40.5 49.4 2.9 8.6 11.6 0.0 0.0 40.1 1.5 0.0 0.0 16.9 219.1 2.0 41.1 14.4 0.0 2.5 45.2 2.9 4.8 57.8 1.1 3.6 1.3 0.9 9.3 4.2 3.8 0.0 22.5 0.3 10.2 0.3 21.1 473.0 17.7 1.5 32.0 68.4 0.7 8.2 0.0 74.9 5.9 64.0 0.0 22.2 3.7 52.0 0.1 0.4 2.7 0.5 6.6 24.5 28.0 10.2 9.8 115.7 137.5 39.0 3.3 0.9 0.1 130.7 FSTL4 KIAA1061 ENSG00000053108 "Follistatin like 4" Q6MZW2 5 133196455-133612541 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.4" "Cell type enriched" "Detected in many" 6 "Excitatory neurons: 390.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "SCLC-21H: 57.2;U-266/70: 19.3;U-266/84: 20.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045920 Uncertain Uncertain Mitochondria "Secreted to blood" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Mitochondria "HPA045920: AB_10965844" "unprognostic (5.52e-2)" "unprognostic (2.54e-1)" "unprognostic (5.74e-2)" "unprognostic (8.14e-2)" "unprognostic (1.87e-1)" "unprognostic (3.97e-2)" "unprognostic (6.35e-2)" "unprognostic (2.30e-1)" "unprognostic (1.11e-1)" "unprognostic (2.01e-1)" "unprognostic (4.74e-2)" "unprognostic (8.66e-2)" "unprognostic (3.73e-4)" "unprognostic (2.02e-2)" "unprognostic (9.91e-3)" "unprognostic (1.03e-2)" "unprognostic (4.25e-2)" 0.1 1.3 5.5 0.6 5.5 1.9 0.6 8.5 11.2 0.3 0.0 1.1 0.7 0.2 1.5 1.9 0.9 0.5 0.3 3.1 3.2 2.8 0.1 1.2 0.3 0.0 6.2 0.4 1.9 3.1 2.3 3.8 0.0 1.6 1.1 3.9 0.7 0.0 0.9 3.4 0.8 0.2 0.0 0.4 1.4 1.7 21.4 1.3 0.8 0.5 1.1 6.0 0.9 7.8 7.5 13.1 1.4 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 12.5 1.7 0.7 10.5 0.0 1.3 0.2 1.7 0.5 0.0 0.9 0.6 0.6 13.9 1.1 0.0 0.0 0.7 0.3 1.8 0.0 0.1 0.3 0.0 0.5 5.9 7.0 0.0 12.7 1.5 0.6 14.4 14.2 1.6 0.6 1.3 14.1 0.0 15.0 57.2 1.6 2.9 2.4 0.3 12.2 4.6 0.5 0.3 0.6 2.4 0.8 0.4 19.3 20.7 0.5 0.2 0.1 0.4 1.1 0.2 0.1 0.2 0.0 0.5 0.6 0.4 0.3 0.1 0.5 0.4 0.2 0.5 0.2 0.2 0.3 0.3 0.3 5.5 5.5 8.5 11.2 3.1 3.2 0.0 6.2 0.0 0.0 21.4 7.8 0.0 0.0 3.1 21.5 1.0 1.7 2.5 0.2 4.0 10.1 0.6 0.3 9.6 0.0 4.4 0.0 14.6 0.4 0.1 0.0 0.0 0.2 35.9 1.2 0.2 0.6 9.0 0.0 390.3 0.0 0.0 0.4 0.0 0.1 0.0 1.4 0.0 0.0 0.1 1.7 57.9 0.4 0.0 0.0 0.0 20.4 0.3 1.2 10.6 8.4 0.0 3.0 0.0 21.1 4.5 0.6 0.0 0.7 0.0 0.4 0.2 2.5 3.7 2.6 6.6 0.0 1.1 0.5 0.7 3.3 1.6 0.0 0.4 0.9 0.1 2.9 FXYD2 "ATP1G1, HOMG2, MGC12372" ENSG00000137731 "FXYD domain containing ion transport regulator 2" P54710 11 117800844-117828698 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Disease variant, FDA approved drug targets, Primary hypomagnesemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "kidney: 3645.4" "Group enriched" "Detected in many" 5 "Cholangiocytes: 1595.6;Distal tubular cells: 2952.4;Ductal cells: 892.8;Proximal tubular cells: 3423.7" "Cancer enriched" "Detected in some" 8 "renal cancer: 49.9" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 4 "memory CD8 T-cell: 14.8;naive CD4 T-cell: 5.1;naive CD8 T-cell: 4.3;NK-cell: 9.6;plasmacytoid DC: 3.8" "Group enriched" "Detected in many" 7 "dendritic cells: 3.8;NK-cells: 9.6;T-cells: 14.8" "Group enriched" "Detected in some" 25 "MOLT-4: 2255.4;RPTEC TERT1: 4711.9" "Low region specificity" "Detected in many" "Region enriched" "Detected in some" 5 "spinal cord: 27.7" "HPA064218, HPA068838" Supported Approved Mitochondria NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA064218: AB_2685214, HPA068838: AB_2686047" "unprognostic (4.11e-4)" "unprognostic (1.14e-2)" "unprognostic (1.63e-1)" "unprognostic (1.36e-3)" "unprognostic (1.09e-3)" "unprognostic (2.30e-2)" "unprognostic (3.65e-2)" "unprognostic (4.62e-1)" "unprognostic (4.01e-2)" "unprognostic (4.91e-2)" "unprognostic (1.24e-2)" "unprognostic (2.64e-1)" "prognostic favorable (3.23e-9)" "unprognostic (3.22e-3)" "unprognostic (4.38e-2)" "unprognostic (4.62e-1)" "unprognostic (3.00e-2)" 2.0 0.9 0.7 1.4 0.6 3.3 1.2 1.4 1.7 1.0 0.0 2.1 1.4 1.5 1.2 0.8 1.8 353.1 1.2 0.8 0.0 3645.4 23.8 4.4 8.9 0.0 0.1 2.4 612.6 0.2 1.6 0.8 0.0 1.7 0.8 1.1 835.6 0.7 0.3 1.0 1.6 2.2 0.0 3.1 2.8 0.6 0.0 74.8 1.0 0.6 4.5 1.8 0.9 0.4 0.0 118.6 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.4 3.5 0.0 0.2 0.4 0.2 0.0 0.3 0.2 0.0 0.1 0.2 83.6 0.1 0.2 0.7 0.0 0.0 0.0 0.0 0.0 1.9 140.3 0.0 0.0 0.2 0.3 2255.4 0.0 1.2 0.0 0.0 0.6 0.0 4.6 4711.9 0.0 1.9 0.0 0.0 2.9 0.2 0.2 0.8 0.3 0.8 0.0 1.3 0.5 0.0 1.0 0.3 0.2 0.1 0.2 0.0 0.0 1.2 0.0 1.0 0.0 1.0 0.2 1.8 14.8 0.2 0.3 5.1 4.3 0.0 9.6 0.0 3.8 1.7 2.1 0.7 0.6 1.4 1.7 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.4 1.0 0.0 0.6 0.0 33.6 1.1 0.1 0.8 0.6 0.2 0.1 0.5 1.2 1595.6 0.1 435.9 0.0 0.1 0.7 0.0 2952.4 892.8 21.8 1.6 4.1 2.2 15.1 2.7 0.0 10.0 0.1 3.5 0.5 41.3 0.0 0.6 4.2 3.9 3.6 0.0 0.0 0.3 16.2 4.5 4.1 25.9 9.3 24.8 0.0 0.0 8.8 0.5 1.0 0.0 0.0 23.2 0.0 7.5 0.4 0.2 0.0 3423.7 0.1 3.3 6.6 1.6 3.8 0.3 0.3 0.2 0.9 0.3 27.7 1.2 0.1 0.0 GATB "PET112, PET112L" ENSG00000059691 "Glutamyl-tRNA amidotransferase subunit B" O75879 4 151670504-151761007 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein biosynthesis" Ligase "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Muller glia cells: 333.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042610 Uncertain Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 5: Muller glia cells - Visual perception" Mitochondria "HPA042610: AB_10797502" "unprognostic (2.52e-1)" "unprognostic (3.33e-1)" "unprognostic (1.01e-3)" "unprognostic (5.08e-2)" "unprognostic (2.31e-1)" "unprognostic (6.91e-2)" "unprognostic (2.24e-1)" "unprognostic (5.77e-2)" "unprognostic (2.06e-1)" "unprognostic (6.76e-2)" "unprognostic (1.37e-1)" "unprognostic (8.17e-2)" "prognostic favorable (1.20e-10)" "unprognostic (1.91e-1)" "unprognostic (8.39e-2)" "unprognostic (3.09e-2)" "unprognostic (2.46e-1)" 11.8 15.6 15.4 5.6 17.5 9.5 8.3 18.0 20.4 6.7 14.9 9.8 5.8 5.5 8.3 10.3 8.7 5.5 33.3 16.3 16.9 21.6 22.2 5.3 7.6 17.4 16.5 11.3 5.3 18.3 5.2 8.6 17.1 5.5 9.6 17.0 7.9 6.4 23.0 9.4 6.4 8.0 17.7 6.5 8.2 8.0 17.2 12.2 7.5 40.3 9.7 6.9 6.1 20.4 14.9 11.6 16.1 15.7 22.9 21.7 13.9 19.3 24.9 33.3 25.8 19.5 23.8 20.2 5.0 20.1 20.3 13.7 34.5 36.6 35.3 11.4 21.1 9.4 15.2 40.7 22.4 19.1 9.0 22.8 23.1 32.0 11.2 19.2 25.1 28.0 36.8 17.1 26.0 16.7 24.1 20.8 16.6 12.4 21.1 20.4 15.5 16.1 30.2 12.3 16.5 18.5 15.8 21.1 23.1 15.4 17.9 13.7 14.1 16.8 9.1 11.7 13.4 20.3 28.2 16.8 23.7 16.9 12.5 0.9 11.6 2.0 4.5 16.9 7.3 11.4 6.1 6.5 20.9 9.9 7.8 7.3 1.1 8.7 12.1 8.1 7.0 10.8 15.4 17.5 18.0 20.4 16.3 16.9 17.4 16.5 17.1 17.7 17.2 20.4 4.3 9.6 4.8 11.4 6.7 0.0 6.0 0.0 5.7 9.8 6.3 7.1 64.8 1.5 3.7 11.0 8.4 23.4 2.9 3.2 27.4 11.2 8.0 6.7 7.3 4.4 2.4 15.6 28.4 7.4 16.6 8.8 6.6 7.1 1.3 12.3 2.5 17.2 17.1 10.1 16.4 4.2 0.0 7.3 0.0 10.6 5.3 7.6 0.0 15.9 10.8 333.3 1.0 14.1 27.5 6.9 4.9 4.5 5.6 3.1 6.3 22.7 1.5 17.1 6.6 6.5 5.9 14.3 14.0 10.6 0.0 13.4 3.6 12.5 7.1 4.5 GATM AGAT ENSG00000171766 "Glycine amidinotransferase" P50440 15 45361124-45402327 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 12 "kidney: 2099.3;liver: 2804.2;pancreas: 2935.3" "Group enriched" "Detected in many" 8 "Hepatocytes: 1495.2;Proximal tubular cells: 3703.0" "Cancer enhanced" "Detected in all" "liver cancer: 135.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "memory B-cell: 11.0;myeloid DC: 6.6;naive B-cell: 5.4;plasmacytoid DC: 6.8" "Group enriched" "Detected in many" 5 "B-cells: 11.0;dendritic cells: 6.8" "Group enriched" "Detected in many" 4 "RH-30: 210.1;RT4: 55.8;U-266/70: 126.3;U-266/84: 165.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026077 Enhanced Supported Mitochondria NA NA 600000 "Cluster 43: B-cells - Humoral immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA026077: AB_1849528" "unprognostic (1.91e-1)" "unprognostic (1.33e-2)" "unprognostic (2.77e-2)" "unprognostic (6.57e-2)" "unprognostic (9.43e-2)" "unprognostic (1.67e-2)" "unprognostic (6.99e-3)" "unprognostic (1.04e-1)" "unprognostic (4.51e-2)" "unprognostic (3.36e-2)" "unprognostic (1.33e-1)" "unprognostic (5.67e-2)" "prognostic favorable (1.38e-4)" "unprognostic (1.09e-1)" "unprognostic (4.07e-2)" "unprognostic (3.60e-2)" "unprognostic (1.80e-1)" 14.4 21.4 133.9 12.4 138.4 1.8 25.4 152.5 216.5 9.9 94.3 19.6 175.5 8.4 10.5 25.1 11.6 47.7 57.2 131.1 140.9 2099.3 2804.2 7.3 18.4 148.0 135.4 165.2 2935.3 2.7 8.3 74.7 153.4 12.4 11.5 7.5 57.5 15.1 142.5 137.6 110.2 14.5 149.2 33.6 99.2 78.2 140.4 12.6 63.0 46.9 29.7 18.0 15.5 181.2 12.9 6.5 4.4 0.6 0.1 0.2 0.8 0.1 0.1 0.0 0.2 1.4 21.4 34.4 1.0 0.0 5.7 2.2 17.0 0.6 0.4 1.9 0.3 2.8 0.4 0.3 0.8 20.7 2.6 0.8 0.7 0.0 0.4 0.0 0.3 7.8 0.4 0.7 0.2 0.6 2.2 0.6 11.2 31.3 0.0 0.5 210.1 1.5 3.5 55.8 23.5 4.1 6.9 0.4 1.2 2.1 2.9 23.7 0.0 0.0 0.5 0.2 6.3 126.3 165.5 0.8 1.6 0.3 1.0 0.0 1.1 0.3 0.2 1.6 0.0 11.0 0.0 0.2 6.6 5.4 0.0 1.4 0.0 0.1 0.6 6.8 0.0 1.0 133.9 138.4 152.5 216.5 131.1 140.9 148.0 135.4 153.4 149.2 140.4 181.2 2.4 3.2 1.1 67.3 42.3 54.3 14.9 5.2 5.7 8.1 16.9 9.5 35.5 228.8 5.4 71.7 0.0 1.0 0.8 3.1 295.4 58.2 8.8 1.3 0.4 7.3 0.0 29.3 6.8 290.0 1.2 19.8 69.8 2.7 3.8 219.5 23.9 1495.2 89.6 8.4 3.3 3.1 2.0 80.3 80.3 18.3 4.4 50.6 23.2 20.6 3.1 19.1 2.1 57.3 196.3 97.3 3.9 3.4 7.2 6.4 98.4 3703.0 1.9 3.8 6.6 38.4 16.8 22.0 9.7 16.0 133.7 1.8 17.6 4.1 3.4 20.4 GCDH ACAD5 ENSG00000105607 "Glutaryl-CoA dehydrogenase" Q92947 19 12891160-12914207 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Glutaricaciduria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 89.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 115.5;Proximal tubular cells: 147.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043252, HPA048492" Enhanced Supported Mitochondria NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA043252: AB_2678390, HPA048492: AB_2680418" "unprognostic (2.46e-1)" "unprognostic (1.64e-3)" "unprognostic (6.79e-3)" "unprognostic (8.07e-3)" "unprognostic (8.20e-3)" "unprognostic (3.14e-2)" "prognostic favorable (7.28e-5)" "prognostic favorable (3.35e-4)" "unprognostic (1.62e-1)" "unprognostic (3.03e-2)" "unprognostic (7.50e-3)" "unprognostic (7.46e-2)" "prognostic favorable (6.79e-8)" "unprognostic (7.09e-3)" "unprognostic (3.42e-1)" "unprognostic (5.32e-2)" "unprognostic (1.59e-1)" 16.8 17.8 20.2 11.2 22.4 13.0 15.6 22.1 23.3 10.2 21.8 13.2 11.8 12.6 8.6 14.0 15.2 8.4 29.3 19.2 19.4 24.5 89.1 9.3 16.8 20.7 20.9 16.8 15.5 11.5 10.6 5.4 21.0 13.6 8.5 5.5 20.0 11.5 30.5 10.1 13.0 8.2 19.9 12.8 18.6 4.5 20.9 17.8 11.9 27.1 11.9 14.9 9.9 22.7 22.9 14.1 15.0 27.5 21.4 9.8 13.8 17.2 11.1 21.6 15.7 26.9 10.8 33.0 31.9 10.5 10.8 15.6 20.8 16.4 10.6 28.6 22.8 21.0 24.6 33.1 24.8 43.7 18.8 13.8 19.9 15.3 16.1 8.8 18.1 44.4 51.8 11.4 10.7 28.9 51.7 41.7 16.7 22.0 36.1 48.2 15.3 68.9 12.6 12.1 32.3 18.9 22.8 22.6 16.7 9.6 17.8 29.3 13.3 18.0 12.9 29.9 18.2 59.5 32.2 34.6 11.0 50.7 15.4 13.9 13.9 8.5 18.8 12.1 18.8 18.1 23.2 21.0 24.0 19.5 30.9 23.8 3.1 38.8 9.8 14.7 21.4 20.0 20.2 22.4 22.1 23.3 19.2 19.4 20.7 20.9 21.0 19.9 20.9 22.7 6.0 3.2 5.3 25.5 21.2 7.9 14.5 13.3 11.4 14.2 17.3 10.8 10.0 22.8 8.6 11.0 25.0 16.2 17.2 11.6 52.8 14.0 2.6 7.7 10.0 7.3 15.6 60.4 7.1 11.2 21.5 10.2 12.8 10.9 7.0 19.5 13.6 115.5 21.5 8.4 7.4 13.8 16.2 14.4 5.0 1.8 13.1 9.9 17.8 5.6 20.7 18.6 18.6 14.6 15.1 10.2 9.7 12.8 25.4 11.3 17.4 147.8 7.2 12.3 0.0 13.7 9.8 8.3 7.4 13.4 5.3 16.3 20.9 33.0 20.6 12.1 GHITM "DERP2, HSPC282, My021, PTD010, TMBIM5" ENSG00000165678 "Growth hormone inducible transmembrane protein" Q9H3K2 10 84139509-84153568 "Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 1114.2;Late spermatids: 2559.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016464, HPA061664" Approved Supported Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA016464: AB_1849656, HPA061664: AB_2684579" "unprognostic (6.26e-3)" "unprognostic (1.85e-1)" "unprognostic (2.75e-2)" "unprognostic (1.51e-1)" "unprognostic (4.61e-2)" "prognostic unfavorable (1.76e-4)" "unprognostic (5.71e-2)" "unprognostic (4.56e-2)" "unprognostic (1.76e-1)" "unprognostic (1.28e-1)" "unprognostic (8.14e-2)" "unprognostic (5.71e-2)" "prognostic favorable (2.32e-10)" "unprognostic (2.46e-2)" "unprognostic (2.09e-1)" "unprognostic (3.56e-2)" "unprognostic (1.25e-1)" 113.9 179.5 124.3 87.0 133.3 110.6 93.8 138.6 147.7 73.1 150.6 171.2 163.5 76.8 86.1 114.4 71.4 68.9 365.3 136.1 146.1 300.7 271.1 74.1 87.3 136.6 128.1 72.7 77.7 197.3 88.8 70.3 138.5 80.6 166.4 144.3 94.4 84.2 369.3 79.7 137.1 85.7 125.4 73.8 123.1 115.7 137.5 86.5 105.9 456.6 103.3 92.3 76.5 123.1 228.2 230.8 97.1 223.5 162.6 143.3 171.6 153.3 267.4 193.7 180.2 283.1 183.8 178.9 167.7 203.2 170.9 199.9 208.4 200.0 185.9 179.8 157.4 127.7 227.3 281.0 306.5 402.0 200.0 162.7 384.1 200.4 577.8 201.8 169.9 150.5 299.9 324.3 180.4 197.4 143.6 318.9 98.3 184.8 203.2 128.3 89.4 270.5 271.4 179.2 79.4 92.4 154.7 134.1 325.1 111.2 273.7 254.2 145.3 94.0 126.5 138.5 251.1 227.9 265.7 199.9 246.8 364.4 67.1 293.7 284.9 276.5 173.9 304.7 194.2 211.0 178.9 186.0 279.9 177.9 166.6 178.8 223.7 206.7 281.3 145.3 235.3 578.0 124.3 133.3 138.6 147.7 136.1 146.1 136.6 128.1 138.5 125.4 137.5 123.1 94.1 96.1 87.6 23.2 138.0 170.3 185.1 440.9 87.0 135.9 102.2 71.8 689.3 140.2 235.8 158.2 70.9 260.4 134.0 376.0 579.2 295.3 1114.2 58.7 68.6 120.7 125.6 242.9 33.6 232.3 234.9 119.6 107.6 67.1 102.0 79.3 88.5 326.1 267.7 101.0 34.5 206.0 443.5 156.2 169.2 2559.1 110.3 153.0 163.7 16.9 228.3 269.0 114.4 14.6 24.3 223.3 276.3 136.9 167.3 180.1 343.7 802.9 173.4 159.9 144.7 114.5 219.8 263.1 153.2 150.4 170.3 386.0 141.6 158.4 281.4 212.9 GJB2 "CX26, DFNA3, DFNB1, NSRD1" ENSG00000165474 "Gap junction protein beta 2" P29033 13 20187463-20192938 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Hearing "Deafness, Disease variant, Ectodermal dysplasia, Ichthyosis, Non-syndromic deafness, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 328.1;esophagus: 812.1;vagina: 519.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 69.8;Basal respiratory cells: 237.4;Basal squamous epithelial cells: 55.8;Ionocytes: 50.8;Squamous epithelial cells: 160.9" "Cancer enhanced" "Detected in all" "head and neck cancer: 447.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "CAPAN-2: 144.6;hTCEpi: 105.4;OE19: 76.9;RT4: 169.9" "Low region specificity" "Detected in all" "CAB013093, HPA014362" Uncertain Approved Mitochondria NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Mitochondria "CAB013093: AB_2533903, HPA014362: " "unprognostic (2.21e-1)" "unprognostic (1.25e-3)" "unprognostic (2.43e-2)" "unprognostic (6.14e-2)" "prognostic unfavorable (4.45e-4)" "unprognostic (9.77e-2)" "unprognostic (2.92e-1)" "prognostic unfavorable (6.25e-4)" "unprognostic (1.33e-1)" "unprognostic (3.69e-3)" "prognostic unfavorable (2.90e-4)" "unprognostic (3.22e-2)" "prognostic unfavorable (2.53e-6)" "unprognostic (5.78e-3)" "unprognostic (2.40e-1)" "unprognostic (1.17e-2)" "unprognostic (8.93e-3)" 2.0 0.7 1.3 6.7 1.2 3.8 3.7 2.4 3.1 328.1 5.3 20.8 12.9 2.9 3.4 812.1 0.9 14.0 0.4 1.1 1.7 9.8 47.5 0.7 0.4 1.8 1.7 0.3 1.3 0.1 4.1 0.2 1.7 1.2 17.4 0.0 145.2 0.3 0.4 73.0 10.6 2.6 1.7 0.2 8.1 1.2 7.6 12.5 1.7 1.2 90.4 27.9 519.8 1.6 8.7 0.6 0.0 0.2 0.0 2.9 1.7 0.0 0.0 0.0 0.0 1.3 144.6 0.0 0.7 0.1 1.1 28.9 5.3 14.4 0.1 12.6 1.8 0.1 0.1 0.3 0.0 0.0 5.1 2.4 105.4 1.9 19.5 0.0 0.0 2.1 0.1 10.7 0.2 1.4 1.3 0.0 0.3 76.9 14.4 0.2 0.0 8.3 0.2 169.9 0.1 0.0 0.3 0.1 0.3 1.9 2.2 0.4 0.0 0.2 0.0 2.5 22.2 8.7 9.6 0.0 17.1 0.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.2 2.4 3.1 1.1 1.7 1.8 1.7 1.7 1.7 7.6 1.6 0.1 3.2 0.0 2.0 0.6 69.8 16.1 237.4 55.8 0.0 1.3 1.3 0.5 4.3 37.3 1.8 0.0 0.1 0.0 28.0 0.0 4.4 1.5 5.0 1.5 1.3 4.2 0.0 0.0 9.8 0.2 1.7 4.1 19.1 0.0 0.0 0.0 25.2 0.6 0.0 0.0 6.1 50.8 0.6 13.3 1.3 0.0 3.9 1.8 0.0 4.6 0.0 0.0 0.0 0.0 9.2 13.3 0.0 2.7 8.6 10.7 17.5 7.5 0.0 0.0 0.1 4.7 0.8 2.1 160.9 28.7 0.1 0.9 0.0 25.0 21.7 GLCE "HSEPI, KIAA0836" ENSG00000138604 "Glucuronic acid epimerase" O94923 15 69160584-69272217 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 79.0;Microglial cells: 76.8;Oligodendrocytes: 154.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 35.8" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 8 "dendritic cells: 1.9;monocytes: 2.3;T-cells: 2.0" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 119.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040481, HPA048216" Uncertain Approved Mitochondria "Intracellular and membrane" NA NA 240000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA040481: AB_2677004, HPA048216: AB_2680317" "unprognostic (1.30e-1)" "unprognostic (2.39e-1)" "unprognostic (1.20e-3)" "unprognostic (7.77e-2)" "unprognostic (1.58e-1)" "unprognostic (5.55e-3)" "unprognostic (1.00e-1)" "unprognostic (2.84e-1)" "unprognostic (1.48e-1)" "unprognostic (2.56e-1)" "unprognostic (7.47e-2)" "unprognostic (1.41e-1)" "unprognostic (2.40e-2)" "unprognostic (1.53e-1)" "unprognostic (6.00e-2)" "unprognostic (5.23e-1)" "unprognostic (4.07e-2)" 9.1 12.2 6.7 5.6 7.8 0.9 8.9 35.8 6.2 8.2 8.4 12.8 14.2 6.4 6.9 10.0 5.5 7.5 6.3 6.0 6.7 13.3 16.8 8.4 3.5 5.7 8.5 12.7 4.7 8.7 6.4 13.4 7.2 5.8 14.2 13.2 10.9 5.8 4.1 10.4 11.5 7.0 7.5 4.4 9.1 3.9 8.8 4.9 4.1 4.9 5.1 6.6 4.6 8.0 9.6 8.5 5.6 9.7 18.6 17.6 2.0 17.6 23.2 13.3 25.2 7.1 23.6 5.8 8.5 14.4 16.8 14.0 12.1 11.4 27.1 2.2 13.4 9.7 15.0 7.2 17.9 4.2 19.0 12.1 7.8 16.6 18.6 9.7 119.4 4.3 3.9 6.0 25.4 5.9 2.6 7.4 2.7 9.7 5.9 5.8 22.6 7.3 12.3 10.1 17.9 3.7 18.0 11.0 38.1 3.8 7.9 5.8 41.8 12.7 15.7 14.3 15.8 2.5 3.7 1.3 12.9 7.0 18.8 0.0 2.1 0.0 0.3 1.6 0.5 0.2 0.8 0.4 1.8 0.2 0.5 0.7 0.0 0.2 2.3 1.9 2.0 0.9 6.7 7.8 35.8 6.2 6.0 6.7 5.7 8.5 7.2 7.5 8.8 8.0 16.9 0.0 15.4 4.9 6.2 4.8 10.1 8.3 26.2 10.3 18.8 19.4 8.1 7.2 8.8 11.0 10.4 22.7 12.1 21.3 5.9 13.0 3.9 4.0 5.4 22.6 20.4 9.4 79.0 13.8 12.7 14.0 28.1 4.9 2.5 11.8 16.4 27.2 16.4 8.4 41.5 27.1 10.2 13.3 4.4 5.1 6.2 10.7 8.8 76.8 13.7 13.1 4.1 35.7 154.9 16.9 28.2 17.7 7.1 5.3 32.4 18.3 18.2 16.6 13.1 6.6 9.4 29.8 25.9 27.9 6.5 33.0 5.9 17.1 26.4 13.3 GLOD5 ENSG00000171433 "Glyoxalase domain containing 5" A6NK44 X 48761747-48773648 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "epididymis: 5.8;intestine: 10.6;kidney: 11.2;liver: 8.2" "Group enriched" "Detected in some" 4 "Proximal enterocytes: 45.2;Proximal tubular cells: 70.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "MCF7: 2.1" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA010667 Enhanced Uncertain Mitochondria NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA010667: AB_1078975" "unprognostic (1.03e-1)" "unprognostic (2.61e-1)" "unprognostic (7.78e-2)" "unprognostic (7.04e-2)" "unprognostic (3.14e-1)" "unprognostic (6.11e-2)" "unprognostic (1.80e-2)" "unprognostic (2.64e-1)" "unprognostic (2.76e-1)" "unprognostic (2.21e-1)" "unprognostic (1.05e-8)" "unprognostic (2.08e-2)" "unprognostic (1.73e-1)" "unprognostic (5.07e-2)" "unprognostic (6.79e-4)" 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.0 0.1 0.3 0.0 4.7 10.6 0.0 5.8 0.1 1.9 0.8 0.0 0.0 0.0 11.2 8.2 1.3 0.0 0.1 0.0 0.0 0.7 0.1 0.3 0.0 0.1 0.2 6.1 1.9 0.3 0.3 0.0 0.0 10.0 0.1 0.0 0.0 1.4 0.1 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 3.2 2.6 1.3 0.5 0.0 0.3 0.2 0.0 0.6 8.3 1.0 0.0 4.3 0.3 7.3 0.0 0.1 0.0 14.4 13.7 0.6 0.2 3.0 0.1 0.0 1.2 2.7 0.2 0.9 0.1 0.0 0.0 1.1 0.0 0.1 0.0 8.0 0.0 0.0 0.3 7.3 0.0 0.3 0.0 0.2 0.0 0.5 0.0 0.0 0.6 0.5 0.0 0.5 0.5 0.8 13.9 0.0 0.1 0.3 45.2 70.5 2.7 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 8.9 0.7 GLRX5 "C14orf87, GRX5, PR01238" ENSG00000182512 "Glutaredoxin 5" Q86SX6 14 95533503-95544724 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 195.0" "Cell type enhanced" "Detected in all" "Distal tubular cells: 518.5;Erythroid cells: 1134.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042465, HPA063716" Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 6: Erythroid cells - Oxygen transport" Mitochondria "HPA042465: AB_10794048, HPA063716: AB_2685102" "unprognostic (2.57e-1)" "unprognostic (6.76e-2)" "unprognostic (1.60e-2)" "unprognostic (2.69e-2)" "unprognostic (3.72e-2)" "unprognostic (2.43e-3)" "unprognostic (1.29e-1)" "unprognostic (5.41e-2)" "unprognostic (8.28e-2)" "prognostic favorable (1.08e-5)" "unprognostic (1.85e-1)" "unprognostic (1.02e-1)" "prognostic favorable (7.83e-10)" "unprognostic (1.44e-1)" "unprognostic (3.81e-2)" "unprognostic (2.66e-2)" "unprognostic (8.91e-2)" 37.2 52.1 44.1 17.6 44.9 178.8 27.2 43.8 50.2 22.3 46.7 44.8 46.2 19.2 39.0 24.5 23.6 17.5 76.9 46.6 45.8 74.5 105.5 18.3 23.1 43.3 44.5 32.8 31.5 46.3 18.9 37.8 44.3 26.8 37.3 10.1 29.3 29.6 195.0 18.3 33.2 24.4 42.9 20.8 34.2 35.7 46.2 40.3 26.7 168.9 27.0 24.5 15.0 42.9 77.1 92.7 61.4 68.0 74.2 57.5 202.0 54.9 56.1 69.4 69.1 124.8 87.5 111.7 77.4 42.8 39.2 75.5 116.5 79.6 71.5 68.5 94.4 100.3 63.4 202.2 73.5 160.9 96.5 55.4 74.1 49.9 81.1 28.1 76.1 94.4 115.7 88.3 61.2 205.5 133.6 165.9 81.5 89.7 107.8 220.8 184.3 67.8 93.3 89.3 127.9 75.2 54.8 81.3 87.7 59.9 107.7 72.6 55.6 30.5 65.0 77.6 85.7 41.7 57.9 92.0 67.2 99.8 72.2 0.4 2.9 4.8 3.4 4.3 4.9 4.6 4.6 6.0 4.7 5.4 3.7 3.9 1.3 3.9 2.7 9.0 6.2 1.8 44.1 44.9 43.8 50.2 46.6 45.8 43.3 44.5 44.3 42.9 46.2 42.9 78.7 28.9 30.0 7.8 41.1 108.5 58.7 7.5 61.5 38.5 112.8 135.9 150.0 64.3 10.4 95.6 33.3 97.8 66.5 76.3 518.5 15.2 312.0 49.7 61.5 58.9 54.0 1134.9 15.0 15.6 164.9 66.2 46.4 48.3 14.7 110.3 47.2 147.2 58.7 50.5 16.4 72.1 4.1 41.7 58.7 90.2 54.3 50.7 87.2 7.5 21.3 128.1 52.5 12.5 15.2 15.2 39.5 73.7 75.2 108.2 51.8 281.4 9.1 43.0 59.2 61.1 92.7 115.4 79.0 102.2 124.9 53.8 48.8 169.0 88.0 76.6 GLS "GLS1, KIAA0838" ENSG00000115419 Glutaminase O94925 2 190880821-190965552 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Cataract, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 316.8" "Cell type enhanced" "Detected in all" "Collecting duct cells: 391.8;Excitatory neurons: 427.1;Proximal tubular cells: 539.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "EFO-21: 907.3;RPTEC TERT1: 419.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036223 Enhanced Supported Mitochondria "Intracellular and membrane" No No 92000 "Cluster 44: Non-specific - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA036223: AB_10669984" "unprognostic (7.45e-2)" "unprognostic (3.42e-2)" "unprognostic (3.21e-1)" "prognostic unfavorable (3.45e-4)" "unprognostic (1.17e-1)" "unprognostic (2.08e-3)" "unprognostic (2.51e-3)" "unprognostic (4.24e-2)" "unprognostic (1.59e-1)" "unprognostic (2.40e-1)" "unprognostic (8.01e-2)" "unprognostic (9.06e-2)" "unprognostic (5.41e-2)" "unprognostic (1.62e-1)" "unprognostic (5.03e-2)" "unprognostic (2.13e-1)" "unprognostic (4.12e-1)" 37.0 77.4 38.5 45.7 50.5 28.7 32.0 40.5 74.6 31.0 35.6 32.0 92.2 28.8 26.6 16.8 25.1 41.8 34.7 55.5 35.9 316.8 11.7 55.6 68.0 44.7 19.8 28.9 36.9 62.0 19.9 35.8 52.5 20.8 30.1 81.8 20.4 31.2 15.8 28.5 103.4 36.9 12.0 49.3 18.7 16.2 24.1 41.7 35.7 23.6 57.9 36.5 23.6 44.8 43.6 47.2 32.4 43.1 99.7 68.9 84.0 126.8 95.7 90.6 103.1 58.1 42.1 88.5 907.3 269.3 46.1 55.6 58.0 50.0 131.5 219.8 37.7 147.3 69.1 72.2 90.8 87.2 66.5 62.9 51.0 71.2 48.4 90.1 119.3 36.7 69.3 175.2 203.3 22.8 59.2 83.7 86.9 25.7 76.7 74.2 83.7 77.4 419.2 78.9 44.9 46.8 172.8 37.9 169.2 115.1 14.9 53.0 85.3 129.4 94.5 65.9 156.8 56.2 138.9 122.1 46.7 70.6 105.5 6.4 1.0 1.9 3.7 1.5 6.5 3.4 4.4 4.8 1.6 3.8 4.5 5.5 2.1 2.8 1.1 3.6 4.1 1.1 38.5 50.5 40.5 74.6 55.5 35.9 44.7 19.8 52.5 12.0 24.1 44.8 81.0 189.1 122.5 61.0 89.3 174.5 44.7 15.6 60.9 93.5 51.8 49.5 38.2 35.8 28.4 391.8 210.6 4.4 128.0 100.6 50.9 21.4 6.6 33.7 66.8 68.3 59.2 17.9 427.1 24.5 15.6 66.0 46.4 97.9 36.8 48.2 63.5 4.3 29.1 26.9 270.5 36.7 14.2 31.2 230.0 7.3 28.6 84.3 88.9 143.4 68.4 11.9 55.6 163.3 146.9 29.8 92.9 43.2 118.4 70.1 165.9 539.1 17.0 111.9 19.7 71.6 76.0 11.3 12.9 61.7 162.8 4.0 114.0 97.8 43.6 56.7 GLT8D1 "AD-017, FLJ14611" ENSG00000016864 "Glycosyltransferase 8 domain containing 1" Q68CQ7 3 52694486-52706032 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 149.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010588 Approved Approved Mitochondria NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 23: Testis - Cell cycle regulation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "HPA010588: AB_1078098" "unprognostic (1.37e-1)" "unprognostic (2.96e-1)" "unprognostic (1.38e-2)" "prognostic favorable (2.76e-4)" "unprognostic (3.17e-2)" "unprognostic (1.55e-1)" "unprognostic (2.03e-1)" "unprognostic (1.82e-3)" "unprognostic (7.12e-2)" "unprognostic (9.81e-2)" "unprognostic (1.23e-1)" "unprognostic (1.07e-1)" "unprognostic (5.82e-3)" "unprognostic (2.42e-3)" "unprognostic (3.97e-1)" "unprognostic (3.34e-2)" "unprognostic (6.21e-2)" 33.1 39.8 25.4 22.5 26.6 9.3 35.6 25.2 29.3 47.5 35.6 27.7 25.9 35.0 41.3 18.3 54.4 29.8 32.6 26.2 26.7 40.4 69.5 29.6 25.3 24.0 26.9 53.8 35.7 46.0 64.8 48.2 25.5 30.5 32.3 32.2 29.9 32.7 20.8 22.6 23.4 32.2 25.9 24.6 28.9 64.5 26.4 29.2 64.0 24.6 26.8 31.6 28.6 28.6 28.7 33.2 65.7 52.0 142.6 179.8 36.8 70.3 107.8 60.6 69.1 15.5 52.6 24.0 19.7 122.7 73.3 31.9 42.1 72.0 79.5 43.5 30.6 22.8 61.4 71.7 68.3 34.0 68.5 104.1 62.9 52.1 66.8 139.8 91.3 40.6 29.4 53.6 80.6 29.2 23.4 51.8 33.8 49.8 61.5 17.4 37.3 81.9 71.3 30.8 26.9 46.5 58.6 27.9 48.9 61.2 47.7 44.2 67.1 43.7 33.9 63.9 39.6 60.2 73.7 26.4 76.0 53.2 56.2 38.4 13.0 21.8 19.1 8.5 18.3 14.1 22.2 20.0 11.8 9.8 22.3 15.6 6.9 30.3 9.3 23.1 16.8 10.9 25.4 26.6 25.2 29.3 26.2 26.7 24.0 26.9 25.5 25.9 26.4 28.6 25.8 0.0 9.6 16.0 16.0 12.1 16.1 40.3 13.6 41.5 18.1 19.7 15.3 17.2 23.8 18.4 12.5 58.4 26.5 9.4 23.5 34.4 71.4 38.5 38.4 22.7 18.6 8.6 17.9 27.1 63.5 59.2 14.8 15.2 5.7 35.6 34.2 38.2 26.9 21.9 16.8 21.1 30.5 13.6 12.0 23.0 53.7 12.3 24.9 8.4 26.5 37.0 34.0 15.6 14.6 23.3 16.9 48.5 39.1 14.7 22.8 21.5 44.4 21.3 26.3 31.6 25.2 149.5 50.0 10.3 8.0 26.1 21.4 74.2 17.3 10.0 GLUD1 "GDH, GLUD" ENSG00000148672 "Glutamate dehydrogenase 1" P00367 10 87050202-87094843 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 816.4" "Cell type enhanced" "Detected in all" "Astrocytes: 294.1;Hepatocytes: 402.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 555.0" "Low region specificity" "Detected in all" "HPA042492, HPA044839, HPA061369" Approved Supported Mitochondria "Intracellular and membrane" NA NA 23000000 "Cluster 26: Non-specific - Mitochondria" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 41: Macrophages - Immune response" Mitochondria "HPA042492: AB_2678024, HPA044839: AB_2679107, HPA061369: AB_2684494" "unprognostic (1.48e-1)" "unprognostic (1.26e-2)" "unprognostic (3.55e-1)" "unprognostic (1.07e-1)" "prognostic favorable (3.81e-4)" "unprognostic (1.31e-1)" "unprognostic (1.91e-2)" "unprognostic (5.50e-2)" "unprognostic (2.06e-1)" "unprognostic (4.57e-3)" "prognostic unfavorable (1.76e-5)" "unprognostic (1.13e-1)" "prognostic favorable (1.44e-6)" "unprognostic (2.29e-1)" "unprognostic (4.23e-2)" "unprognostic (7.19e-2)" "unprognostic (4.27e-2)" 70.1 93.0 217.2 44.8 219.0 29.2 96.4 180.4 216.8 50.2 135.8 63.4 80.9 48.1 30.0 77.0 47.4 53.3 75.6 193.3 223.2 249.2 816.4 57.7 42.9 220.9 222.9 71.6 66.2 39.0 37.1 58.8 202.3 110.5 61.5 90.2 55.6 53.2 51.1 84.2 88.6 53.3 223.2 46.4 57.0 22.3 254.6 44.8 68.1 64.4 59.2 68.1 55.6 202.3 127.1 100.3 77.1 131.5 143.0 174.5 84.0 97.7 167.8 92.4 100.5 233.0 120.6 141.5 77.8 143.4 53.0 194.7 101.4 98.5 98.0 102.7 79.8 69.0 55.9 555.0 318.1 163.2 95.5 121.3 181.5 103.2 304.9 140.3 112.0 109.3 70.7 124.0 101.0 92.1 148.1 145.7 88.2 136.9 79.8 110.4 98.3 93.1 267.4 101.8 39.7 73.9 87.8 68.8 126.1 73.9 94.3 112.8 112.4 47.8 42.5 98.2 101.0 73.6 81.4 167.5 115.3 182.8 29.3 9.1 14.2 9.7 8.3 11.1 10.3 9.8 11.2 10.1 15.9 11.3 9.9 8.0 1.2 13.6 16.0 5.9 12.6 6.5 217.2 219.0 180.4 216.8 193.3 223.2 220.9 222.9 202.3 223.2 254.6 202.3 49.3 22.4 23.9 294.1 56.6 106.0 57.5 32.2 105.3 22.5 83.3 38.2 60.2 57.2 47.3 60.7 37.5 95.7 45.6 56.1 156.5 32.5 14.2 37.3 44.0 54.1 39.4 52.6 35.8 33.8 63.8 89.0 86.2 59.7 43.2 33.6 50.7 402.3 69.1 15.2 38.0 49.5 36.7 74.1 184.5 26.0 88.0 81.4 104.9 42.2 50.6 140.0 39.1 48.7 42.9 50.2 38.3 90.7 75.7 103.4 124.2 175.5 21.6 68.9 65.7 41.3 55.9 11.4 8.6 189.5 122.3 47.6 84.6 70.9 49.6 107.3 GLUD2 GLUDP1 ENSG00000182890 "Glutamate dehydrogenase 2" P49448 X 121047610-121050094 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "liver: 3.9;testis: 15.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.6;Cytotrophoblasts: 4.6;Early spermatids: 2.6;Hepatocytes: 4.6;Proximal tubular cells: 3.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 3.7;K-562: 4.3;OE19: 2.1;SK-MEL-30: 5.5;THP-1: 2.7;WM-115: 6.0" "HPA042492, HPA044839, HPA061369" Uncertain Approved Mitochondria NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA042492: AB_2678024, HPA044839: AB_2679107, HPA061369: AB_2684494" "unprognostic (1.44e-1)" "unprognostic (5.49e-2)" "unprognostic (1.90e-2)" "unprognostic (1.39e-2)" "unprognostic (1.27e-3)" "unprognostic (1.29e-1)" "unprognostic (1.77e-2)" "unprognostic (1.24e-1)" "unprognostic (2.23e-1)" "unprognostic (2.42e-1)" "unprognostic (2.61e-1)" "unprognostic (2.35e-1)" "prognostic favorable (1.98e-4)" "unprognostic (1.04e-2)" "unprognostic (1.49e-2)" "unprognostic (4.77e-3)" "unprognostic (5.96e-2)" 1.7 1.7 0.0 0.1 0.3 0.0 1.2 0.0 0.8 0.4 0.5 0.5 0.0 0.4 1.7 0.5 0.4 0.4 0.9 0.4 0.0 1.6 3.9 0.5 0.1 0.0 0.0 0.4 1.0 0.5 0.4 0.8 0.0 0.4 0.0 0.1 0.6 0.2 0.5 0.6 0.4 0.1 0.0 0.1 0.6 15.4 0.1 0.0 0.4 0.1 0.1 0.4 0.4 0.1 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.5 0.0 0.3 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.8 0.0 0.0 0.7 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 5.5 0.1 1.2 2.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.8 0.0 0.0 2.3 0.1 0.0 0.5 0.0 0.6 0.0 0.4 0.1 2.6 0.0 0.0 0.0 2.1 4.6 0.1 0.1 1.9 0.2 2.6 0.6 0.8 0.9 0.0 0.0 1.2 0.4 0.5 0.8 0.0 0.5 0.0 0.1 0.0 4.6 0.5 0.0 0.4 0.1 0.0 1.2 0.3 2.2 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.4 0.2 3.3 0.0 0.1 0.0 0.9 0.4 1.2 1.0 0.1 0.1 2.5 0.3 0.7 0.2 0.3 GLYATL2 "BXMAS2-10, MGC24009" ENSG00000156689 "Glycine-N-acyltransferase like 2" Q8WU03 11 58834065-58904215 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 12.0;cervix: 19.9;salivary gland: 33.4" "Cell type enhanced" "Detected in some" "Breast glandular cells: 14.8;Oligodendrocyte precursor cells: 3.0;Prostatic glandular cells: 3.6;Sertoli cells: 6.6" "Group enriched" "Detected in many" 4 "breast cancer: 16.7;endometrial cancer: 15.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 5.3;BJ hTERT+ SV40 Large T+ RasG12V: 3.7;HAP1: 6.0;SK-BR-3: 14.1;U-2197: 6.6" "Low region specificity" "Detected in many" "HPA060292, HPA065454" Uncertain Approved Mitochondria NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 35: Glandular cells - Unknown function" Mitochondria "HPA060292: AB_2684245, HPA065454: " "unprognostic (1.02e-2)" "unprognostic (3.79e-3)" "unprognostic (8.11e-4)" "prognostic favorable (9.05e-7)" "unprognostic (1.05e-1)" "unprognostic (8.41e-2)" "unprognostic (2.66e-2)" "unprognostic (9.98e-3)" "unprognostic (1.27e-1)" "unprognostic (9.18e-3)" "unprognostic (1.64e-1)" "unprognostic (1.59e-1)" "unprognostic (7.42e-5)" "unprognostic (7.79e-3)" "unprognostic (8.28e-2)" "unprognostic (9.11e-3)" "unprognostic (2.31e-2)" 0.2 0.1 0.2 0.1 0.3 0.1 12.0 0.2 0.5 19.9 0.0 0.1 0.3 0.4 0.3 0.9 0.1 7.5 0.3 0.2 0.4 0.9 0.1 0.0 0.3 0.7 0.2 0.0 0.1 0.0 0.1 0.0 0.6 0.9 0.2 0.3 33.4 0.1 0.0 1.4 0.1 0.3 0.7 0.3 0.1 0.0 0.2 0.1 0.1 0.5 0.4 0.1 0.3 1.1 0.0 0.0 0.4 0.0 0.7 2.6 0.0 1.7 5.3 2.3 3.7 0.0 0.0 0.1 0.0 1.4 1.0 0.4 6.0 0.0 1.9 0.0 1.1 0.0 0.0 0.0 0.2 0.0 0.2 0.5 0.0 0.5 0.2 2.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.1 14.1 0.0 0.0 0.0 0.0 0.0 1.8 0.1 6.6 2.0 0.0 0.0 0.1 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.2 0.5 0.2 0.4 0.7 0.2 0.6 0.7 0.2 1.1 0.2 0.0 0.0 0.0 0.0 1.0 2.3 1.4 0.0 0.5 14.8 2.2 0.1 0.0 1.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.4 1.1 0.0 0.0 1.5 1.4 0.0 0.5 0.0 1.2 0.0 0.4 0.0 0.0 0.1 0.0 1.5 0.0 0.0 0.0 0.4 0.0 0.0 0.3 1.8 0.0 0.0 0.0 0.0 3.0 0.4 0.1 0.0 0.0 0.0 3.6 0.0 0.2 0.1 0.1 6.6 0.2 0.6 0.0 0.1 0.0 2.0 0.0 0.0 0.0 0.0 1.9 GNG12 ENSG00000172380 "G protein subunit gamma 12" Q9UBI6 1 67701475-67833467 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 243.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA057790, HPA062208" Enhanced Supported Approved Mitochondria NA NA 550000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA057790: AB_2683527, HPA062208: AB_2684711" "unprognostic (5.18e-2)" "unprognostic (1.76e-3)" "unprognostic (4.46e-3)" "unprognostic (7.77e-2)" "unprognostic (1.06e-1)" "unprognostic (4.71e-2)" "unprognostic (5.29e-2)" "unprognostic (5.84e-3)" "unprognostic (5.50e-2)" "unprognostic (3.41e-2)" "unprognostic (4.46e-3)" "unprognostic (8.13e-2)" "unprognostic (4.12e-3)" "unprognostic (2.33e-2)" "unprognostic (9.33e-2)" "unprognostic (7.78e-2)" "unprognostic (2.14e-3)" 63.4 57.0 14.4 28.5 12.3 0.3 50.1 10.4 14.0 59.3 13.5 68.4 122.0 59.7 27.7 82.0 43.4 59.3 34.5 13.7 19.5 79.2 44.8 34.3 12.0 21.9 29.1 47.9 25.2 54.7 13.1 60.2 16.9 38.3 65.7 6.6 26.6 47.6 12.9 80.4 110.8 73.9 18.6 56.2 42.7 17.7 16.4 15.9 59.8 19.7 22.7 56.5 46.5 18.7 60.5 55.5 58.0 31.5 241.2 207.9 59.5 182.9 237.2 157.9 141.0 26.5 58.2 0.1 75.9 258.0 98.8 44.2 36.6 150.0 275.7 0.5 28.1 1.0 46.0 0.1 96.0 0.1 3.0 125.7 87.8 168.7 221.8 221.1 251.9 0.0 3.6 0.3 175.6 10.2 0.1 0.5 44.1 65.7 68.3 0.3 119.6 0.9 151.8 53.5 13.2 26.8 126.8 52.1 248.4 48.8 26.9 1.1 326.7 182.5 118.8 332.0 114.5 3.0 0.3 0.5 115.3 7.1 252.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.4 12.3 10.4 14.0 13.7 19.5 21.9 29.1 16.9 18.6 16.4 18.7 49.7 54.5 32.2 54.5 2.1 201.3 78.8 53.3 78.6 2.1 52.4 37.1 26.7 35.8 42.8 58.8 6.2 61.8 0.9 243.1 74.3 96.2 14.6 51.8 20.6 67.0 34.7 5.3 0.5 138.5 105.6 82.6 45.3 49.3 3.8 21.3 76.1 45.6 27.9 3.3 15.3 56.3 30.5 18.2 32.4 16.6 71.4 6.2 78.2 21.5 3.6 3.0 0.0 63.3 1.3 143.7 99.9 75.6 0.2 119.9 227.3 177.9 79.2 18.9 52.6 54.8 71.7 1.8 18.8 83.1 216.8 175.9 4.5 107.1 61.8 109.1 GPAM "GPAT1, KIAA1560, MGC26846" ENSG00000119927 "Glycerol-3-phosphate acyltransferase, mitochondrial" Q9HCL2 10 112149865-112215377 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 305.7;liver: 144.1" "Cell type enhanced" "Detected in many" "Astrocytes: 90.8;Hepatocytes: 184.5;Horizontal cells: 45.4" "Cancer enriched" "Detected in all" 5 "liver cancer: 20.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "ASC diff: 250.3;Hep G2: 71.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046339, HPA060090" Approved Approved Mitochondria NA NA "Cluster 24: B-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Mitochondria "HPA046339: AB_2679627, HPA060090: AB_2684202" "unprognostic (1.82e-1)" "unprognostic (6.28e-2)" "unprognostic (1.13e-1)" "unprognostic (1.30e-1)" "unprognostic (6.80e-2)" "unprognostic (8.75e-2)" "unprognostic (1.40e-2)" "unprognostic (2.16e-2)" "unprognostic (4.59e-1)" "unprognostic (4.80e-1)" "unprognostic (2.37e-2)" "unprognostic (5.44e-2)" "prognostic favorable (4.54e-6)" "unprognostic (2.84e-1)" "unprognostic (4.41e-2)" "unprognostic (2.52e-2)" "unprognostic (1.37e-1)" 305.7 33.9 14.9 4.8 17.1 3.4 67.7 12.2 14.0 3.0 6.9 6.4 4.0 4.2 75.1 2.9 3.1 6.0 12.3 12.4 13.0 4.4 144.1 4.1 4.6 12.9 16.0 5.3 5.0 4.3 2.1 3.0 12.1 3.9 4.7 5.1 17.2 5.3 8.3 3.2 6.1 4.9 11.5 2.9 4.9 5.6 15.7 3.6 12.4 8.8 4.3 4.8 2.6 10.5 9.9 7.4 9.7 12.9 250.3 9.1 12.7 9.2 10.5 6.6 5.1 17.3 5.7 6.9 5.0 6.5 6.1 12.3 15.5 7.9 12.3 5.0 8.4 6.4 7.9 71.8 7.7 11.2 3.4 43.8 13.1 11.7 23.6 49.7 5.8 9.7 8.5 6.1 7.7 5.6 9.6 8.8 8.1 5.6 10.1 9.7 25.4 5.1 4.3 6.8 4.1 12.1 12.8 6.1 14.5 8.9 6.3 4.0 4.4 7.5 4.6 9.4 14.8 6.1 7.3 14.3 8.8 9.8 5.8 0.0 0.3 0.1 0.7 0.4 0.9 0.5 0.5 0.5 0.4 1.1 0.5 0.9 0.0 0.3 0.3 0.6 0.6 0.3 14.9 17.1 12.2 14.0 12.4 13.0 12.9 16.0 12.1 11.5 15.7 10.5 9.1 9.6 27.1 90.8 5.2 0.4 0.8 1.6 4.6 5.3 8.1 8.4 18.9 20.0 4.3 5.5 10.4 5.2 4.3 1.7 1.9 2.7 0.5 5.1 10.0 5.0 1.2 12.2 8.2 3.3 2.9 5.1 3.6 4.2 2.5 12.7 6.4 184.5 3.1 45.4 9.4 3.0 0.0 9.3 1.0 0.9 5.3 1.9 1.8 10.3 1.4 6.1 3.1 10.1 10.1 3.4 2.7 12.0 6.4 1.1 3.7 3.3 4.7 9.1 6.6 4.3 6.6 4.0 3.2 5.4 0.1 1.9 3.3 8.6 5.0 0.6 GPAT2 CT123 ENSG00000186281 "Glycerol-3-phosphate acyltransferase 2, mitochondrial" Q6NUI2 2 96021946-96039451 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Breast glandular cells: 84.5;Sertoli cells: 98.6;Smooth muscle cells: 30.3;Spermatocytes: 64.4;Spermatogonia: 45.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BJ: 8.2;BJ hTERT+ SV40 Large T+: 19.6;BJ hTERT+ SV40 Large T+ RasG12V: 11.6;OE19: 13.9;U-2 OS: 10.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA036841 Uncertain Approved Mitochondria NA NA "Cluster 24: B-cells - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" Mitochondria "HPA036841: AB_10601479" "unprognostic (1.42e-2)" "unprognostic (2.39e-2)" "unprognostic (6.69e-2)" "unprognostic (3.83e-1)" "unprognostic (1.44e-1)" "unprognostic (2.38e-3)" "unprognostic (4.99e-2)" "unprognostic (3.28e-2)" "unprognostic (1.70e-1)" "unprognostic (1.44e-2)" "unprognostic (5.96e-2)" "unprognostic (4.67e-2)" "unprognostic (7.43e-6)" "unprognostic (2.11e-1)" "unprognostic (7.68e-2)" "unprognostic (3.49e-1)" "unprognostic (3.65e-1)" 5.8 0.8 1.5 1.4 1.7 1.2 4.5 1.4 1.7 2.4 3.3 1.8 0.2 1.5 3.1 0.8 1.6 1.6 7.4 1.2 1.3 1.6 1.0 1.3 2.4 1.7 1.6 1.2 1.6 0.1 0.6 1.4 2.0 1.1 1.0 0.2 2.2 2.8 2.1 1.1 2.2 1.6 1.3 4.6 2.1 7.6 2.4 0.8 1.7 3.0 1.9 2.0 1.4 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 8.2 0.0 19.6 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.4 0.0 2.8 0.0 0.0 0.3 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 1.0 0.7 1.0 1.6 0.5 0.7 0.4 2.4 0.3 1.1 0.0 0.1 1.0 0.0 0.5 0.6 1.5 1.7 1.4 1.7 1.2 1.3 1.7 1.6 2.0 1.3 2.4 2.1 12.9 0.0 1.1 0.3 3.5 1.0 1.1 0.7 0.6 0.7 84.5 3.4 1.3 1.5 0.5 1.8 0.0 0.1 1.7 3.1 1.9 2.2 1.9 0.1 0.5 6.5 0.0 0.8 1.0 2.0 0.6 3.3 1.5 0.5 1.3 0.2 10.8 0.0 2.4 8.4 0.4 0.6 0.0 0.8 2.1 5.3 0.6 1.5 1.8 1.9 0.7 1.0 1.0 0.0 1.4 0.8 1.3 0.0 3.6 0.4 0.0 0.2 0.2 0.4 98.6 3.2 30.3 64.4 45.3 0.4 0.1 0.1 2.2 0.3 2.1 1.8 GPD2 ENSG00000115159 "Glycerol-3-phosphate dehydrogenase 2" P43304 2 156435290-156613735 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 151.1;Late spermatids: 95.5;Oligodendrocyte precursor cells: 148.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 3.3;eosinophil: 1.7;intermediate monocyte: 1.6;myeloid DC: 2.7;neutrophil: 1.1;non-classical monocyte: 2.3" "Group enriched" "Detected in many" 5 "dendritic cells: 2.7;granulocytes: 1.7;monocytes: 3.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008012, HPA045506" Enhanced Supported Mitochondria "Intracellular and membrane" NA NA 620000 "Cluster 14: Monocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 68: Oligodendrocytes - Mixed function" Mitochondria "HPA008012: AB_1079013, HPA045506: AB_2679355" "unprognostic (1.30e-1)" "unprognostic (2.50e-1)" "unprognostic (1.08e-1)" "unprognostic (4.79e-3)" "unprognostic (3.25e-1)" "unprognostic (2.39e-2)" "prognostic unfavorable (1.44e-4)" "unprognostic (1.75e-1)" "unprognostic (1.57e-1)" "unprognostic (1.86e-1)" "unprognostic (2.60e-3)" "unprognostic (6.67e-2)" "unprognostic (6.02e-3)" "unprognostic (1.73e-1)" "unprognostic (1.89e-1)" "unprognostic (2.41e-1)" "unprognostic (1.01e-2)" 8.2 5.7 13.3 8.1 17.7 13.4 16.2 15.2 18.6 10.3 6.5 18.6 14.4 6.8 5.2 20.3 18.2 8.9 6.2 19.8 16.3 8.0 3.4 11.4 7.0 13.5 16.2 8.6 6.8 20.5 5.5 6.7 13.1 10.9 18.0 9.6 14.9 7.1 24.7 12.5 15.7 6.1 14.5 8.5 17.4 5.5 18.5 6.1 12.2 14.3 8.6 14.3 9.5 13.6 39.0 27.2 15.3 24.5 32.6 39.6 0.1 48.0 31.2 32.1 38.6 53.9 35.7 8.4 31.9 27.4 13.2 44.5 28.9 44.5 41.4 23.9 9.5 6.0 46.9 0.0 12.0 11.2 12.6 19.5 15.4 55.6 27.1 20.6 24.1 3.7 12.0 1.9 41.7 24.4 0.3 1.0 28.7 15.2 31.0 12.3 9.8 9.2 41.8 50.7 27.3 9.9 45.0 34.4 30.4 25.9 10.9 30.8 22.8 5.7 26.9 26.5 36.5 1.3 0.3 0.4 32.9 3.0 47.1 0.3 3.3 1.7 0.3 1.6 0.5 0.1 0.1 0.4 2.7 0.2 0.3 0.2 1.1 0.4 2.3 0.3 0.5 1.5 13.3 17.7 15.2 18.6 19.8 16.3 13.5 16.2 13.1 14.5 18.5 13.6 12.1 19.2 12.3 151.1 7.8 20.0 23.3 24.9 21.1 5.5 23.4 12.8 13.1 7.2 19.8 22.0 6.2 9.6 6.2 52.1 1.9 9.5 84.8 12.3 6.1 11.3 17.4 6.9 27.9 13.4 15.2 9.2 30.5 23.3 12.7 13.0 10.4 3.4 21.3 5.0 46.9 17.1 10.2 18.6 18.7 95.5 12.2 21.0 24.9 61.8 10.8 4.2 4.1 148.3 48.7 16.2 17.4 7.2 5.6 66.7 16.0 3.9 18.2 11.1 0.0 8.3 12.3 2.6 3.2 41.7 21.5 11.1 7.6 7.0 19.4 77.8 GPT2 ALT2 ENSG00000166123 "Glutamic--pyruvic transaminase 2" Q8TD30 16 46884362-46931289 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Aminotransferase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 267.4;skeletal muscle: 176.4;tongue: 184.5" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 64.3;Hepatocytes: 123.9;Syncytiotrophoblasts: 83.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.3;naive B-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Hep G2: 159.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051514 Approved Approved Mitochondria No No "Cluster 19: B-cells - Humoral immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA051514: AB_2681516" "unprognostic (1.65e-2)" "unprognostic (3.32e-2)" "unprognostic (2.87e-1)" "unprognostic (3.87e-2)" "unprognostic (3.41e-1)" "unprognostic (1.27e-1)" "unprognostic (1.95e-3)" "unprognostic (3.44e-2)" "unprognostic (6.12e-2)" "prognostic favorable (3.17e-4)" "unprognostic (1.90e-1)" "unprognostic (1.30e-1)" "unprognostic (1.56e-1)" "unprognostic (1.44e-2)" "unprognostic (4.86e-1)" "unprognostic (3.54e-3)" "unprognostic (3.18e-1)" 56.8 10.4 51.6 4.0 49.9 3.8 17.0 49.1 56.9 5.2 38.4 7.7 1.7 3.7 31.4 77.8 7.6 9.8 7.9 51.3 45.7 23.5 103.7 2.1 4.3 69.8 45.9 2.3 267.4 8.3 13.0 3.1 63.9 24.2 4.9 6.9 48.8 10.9 176.4 37.8 3.9 3.1 60.2 2.3 58.6 15.0 54.9 7.7 7.6 184.5 13.4 2.7 7.7 64.5 42.6 19.0 23.8 90.6 32.7 7.0 43.1 28.9 10.9 30.7 19.2 65.3 17.6 29.9 24.7 20.7 15.6 33.6 43.3 42.8 20.4 14.0 21.1 10.5 10.8 159.9 22.4 75.6 9.5 15.2 37.0 30.0 46.3 20.3 15.1 56.1 8.7 23.3 10.3 75.8 15.1 62.9 25.3 52.2 54.2 0.3 26.3 71.1 12.4 21.0 73.7 37.7 14.9 76.4 39.0 9.4 19.6 67.6 11.3 21.1 40.9 14.2 23.4 110.2 36.9 87.1 32.6 48.3 11.7 0.4 0.2 0.0 0.1 0.0 0.0 1.3 0.0 0.1 0.4 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 51.6 49.9 49.1 56.9 51.3 45.7 69.8 45.9 63.9 60.2 54.9 64.5 1.3 6.4 3.4 54.9 4.8 15.9 4.9 6.8 64.3 14.5 6.7 8.4 14.9 8.6 9.1 18.4 22.9 9.2 0.3 10.2 11.7 7.0 9.6 12.2 7.2 2.3 13.1 5.2 16.7 30.2 44.8 7.5 37.2 37.5 3.8 14.9 5.0 123.9 3.8 6.7 18.8 13.4 6.1 3.2 7.3 22.9 4.7 2.3 8.8 1.0 1.1 42.5 1.0 13.6 26.0 25.6 5.2 15.4 7.9 12.4 2.0 38.6 5.4 5.9 0.0 5.2 3.6 2.5 17.3 53.1 16.3 83.3 1.4 2.6 6.3 4.2 GREB1L "C18orf6, FLJ13687, KIAA1772" ENSG00000141449 "GREB1 like retinoic acid receptor coactivator" Q9C091 18 21242242-21525417 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 9.2" "Cell type enhanced" "Detected in many" "Granulosa cells: 95.2;Inhibitory neurons: 39.2;Leydig cells: 46.0;Oligodendrocytes: 252.5" "Cancer enhanced" "Detected in some" "breast cancer: 1.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 50.7;BEWO: 100.9;CACO-2: 45.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA041647, HPA044218" Uncertain Approved Mitochondria NA NA "Cluster 38: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "HPA041647: AB_2677597, HPA044218: AB_2678859" "unprognostic (1.88e-3)" "unprognostic (9.01e-4)" "unprognostic (2.92e-1)" "unprognostic (2.45e-1)" "unprognostic (5.03e-2)" "unprognostic (3.67e-3)" "unprognostic (3.65e-1)" "unprognostic (1.11e-2)" "unprognostic (1.07e-1)" "unprognostic (1.97e-1)" "unprognostic (4.32e-3)" "unprognostic (2.87e-2)" "unprognostic (3.30e-8)" "unprognostic (4.72e-3)" "unprognostic (1.89e-1)" "unprognostic (8.80e-2)" "unprognostic (1.35e-1)" 2.6 1.4 5.5 0.1 4.3 0.2 3.3 3.5 3.6 1.2 0.0 0.6 0.1 2.6 2.8 0.2 4.4 0.1 5.3 2.6 8.1 0.4 1.8 0.2 0.1 4.0 4.7 3.7 0.1 0.3 1.2 2.1 4.1 1.6 0.1 3.1 0.5 2.9 9.2 1.3 0.5 0.8 1.7 0.0 0.6 6.2 6.4 0.0 3.8 6.8 0.0 0.1 0.7 4.4 0.0 0.9 50.7 0.0 11.4 0.0 100.9 2.4 2.4 4.3 3.8 45.7 3.7 0.1 5.1 7.6 0.1 9.7 19.4 2.4 7.5 0.7 9.3 0.0 13.4 0.4 0.3 0.0 0.0 0.0 0.7 0.1 9.3 0.5 0.0 1.4 0.0 0.3 10.5 3.5 0.2 0.2 4.9 0.4 6.0 0.2 0.0 2.0 4.8 8.7 3.2 0.0 0.1 1.6 0.2 13.2 2.7 0.2 20.9 0.5 2.9 4.9 0.0 0.1 0.7 0.0 2.2 0.0 0.4 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.5 4.3 3.5 3.6 2.6 8.1 4.0 4.7 4.1 1.7 6.4 4.4 0.4 0.0 0.5 0.7 0.4 0.1 0.1 1.0 0.0 32.3 3.1 1.1 13.4 0.0 1.1 3.7 2.1 3.2 1.8 0.1 0.0 0.2 8.3 2.2 3.4 0.5 0.0 0.0 23.1 0.4 13.2 6.2 0.0 7.0 0.0 95.2 0.0 3.1 0.5 0.0 39.2 0.2 0.0 0.0 1.1 17.9 46.0 0.3 1.8 2.8 0.1 0.8 2.1 8.0 252.5 2.8 0.0 35.7 0.0 0.6 0.3 0.0 2.3 1.6 6.6 2.8 2.3 4.3 5.6 0.0 0.9 1.5 0.3 10.5 1.5 0.2 GRK6 GPRK6 ENSG00000198055 "G protein-coupled receptor kinase 6" P43250 5 177403204-177442901 "Enzymes, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 134.1" "Cell type enhanced" "Detected in many" "Late spermatids: 90.6;NK-cells: 123.6;Plasma cells: 112.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015327, HPA018903" Approved Approved Mitochondria NA NA 170000 "Cluster 52: Eosinophils - Transcription" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Mitochondria "HPA015327: AB_1850334, HPA018903: AB_1850335" "unprognostic (1.06e-1)" "unprognostic (3.39e-2)" "unprognostic (4.46e-2)" "unprognostic (3.87e-2)" "unprognostic (2.35e-3)" "unprognostic (1.53e-1)" "prognostic unfavorable (5.66e-6)" "unprognostic (2.63e-1)" "unprognostic (6.45e-2)" "unprognostic (8.96e-2)" "prognostic favorable (1.22e-4)" "unprognostic (1.74e-2)" "unprognostic (1.99e-2)" "unprognostic (1.83e-3)" "unprognostic (1.15e-1)" "unprognostic (4.00e-2)" "unprognostic (3.47e-1)" 14.0 10.8 12.6 36.7 12.3 134.1 12.7 8.1 16.0 11.3 9.2 19.7 18.5 14.8 2.4 21.5 13.3 12.4 13.3 12.7 9.6 11.0 13.6 21.8 61.6 13.3 10.5 11.1 13.3 5.5 10.5 6.8 11.1 15.8 8.8 2.2 17.9 7.4 15.7 15.5 29.1 9.2 8.9 63.3 15.9 22.3 10.7 35.9 10.2 6.2 30.2 16.6 13.2 13.9 41.1 44.2 15.7 67.8 4.6 7.4 66.4 29.4 15.1 36.2 35.5 103.0 34.1 48.7 44.0 15.6 53.5 29.1 24.3 67.0 14.3 133.9 77.3 43.5 36.2 36.0 24.1 58.6 52.8 11.7 16.1 36.2 21.4 8.8 20.5 87.8 45.6 170.9 11.2 117.4 61.3 61.4 26.7 20.4 48.1 57.1 25.5 71.2 10.7 32.9 36.0 48.6 24.3 42.5 56.8 7.1 32.6 63.4 26.3 29.6 43.8 31.2 75.1 48.8 64.2 40.7 20.0 95.0 29.2 12.7 20.9 74.5 23.6 36.5 17.0 19.3 19.6 21.9 11.9 19.5 20.3 18.0 50.6 40.3 51.9 12.5 26.4 22.6 12.6 12.3 8.1 16.0 12.7 9.6 13.3 10.5 11.1 8.9 10.7 13.9 9.2 0.0 2.2 2.6 71.7 23.7 60.3 4.9 5.7 10.5 14.7 17.3 3.0 10.0 4.6 3.7 6.2 13.9 70.8 18.2 15.6 6.0 37.2 7.4 8.2 6.6 11.4 41.7 3.7 8.3 12.6 9.7 16.8 6.4 14.7 13.9 10.0 6.5 20.4 16.8 3.5 14.3 4.1 29.8 18.8 90.6 6.2 41.2 14.2 2.8 26.4 9.0 123.6 2.0 3.3 10.3 14.0 5.3 112.2 61.1 11.8 8.5 2.0 8.6 13.1 8.4 10.7 3.9 4.2 11.9 20.3 12.7 66.5 12.1 17.1 56.6 GRK7 GPRK7 ENSG00000114124 "G protein-coupled receptor kinase 7" Q8WTQ7 3 141778148-141818490 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Sensory transduction, Vision" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 19 "retina: 11.3" "Cell type enriched" "Detected in some" 73 "Cone photoreceptor cells: 329.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA075093, HPA078232" Enhanced Approved Mitochondria NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 79: Retina - Phototransduction" "Cluster 9: Photoreceptor cells - Phototransduction" Mitochondria "HPA075093: , HPA078232: " "unprognostic (1.11e-1)" "unprognostic (1.70e-2)" "unprognostic (3.35e-3)" "unprognostic (1.22e-2)" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (1.39e-2)" "unprognostic (5.08e-2)" "unprognostic (1.21e-1)" "unprognostic (1.31e-2)" "unprognostic (3.46e-2)" "unprognostic (1.20e-1)" "unprognostic (2.53e-8)" "unprognostic (3.08e-1)" "unprognostic (1.99e-1)" "unprognostic (3.11e-1)" "unprognostic (2.91e-1)" 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.5 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 11.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.1 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.0 3.9 0.1 0.4 0.2 0.0 0.6 1.0 0.1 0.1 0.2 0.0 0.0 0.0 329.4 0.0 0.2 0.0 0.0 0.0 1.0 0.1 0.1 0.1 0.0 0.0 2.5 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.0 2.1 0.0 0.0 0.0 0.4 2.4 0.0 0.1 0.0 1.9 0.1 1.1 0.0 4.5 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.5 0.1 0.1 0.0 0.2 0.3 0.0 0.1 0.3 0.1 0.0 GRPEL1 "FLJ25609, GrpE, hMGE" ENSG00000109519 "GrpE like 1, mitochondrial" Q9HAV7 4 7058895-7068064 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036647 Supported Supported Mitochondria NA NA 23000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA036647: AB_10672359" "unprognostic (6.13e-3)" "unprognostic (3.66e-2)" "unprognostic (1.92e-2)" "unprognostic (6.31e-2)" "unprognostic (9.77e-2)" "unprognostic (2.12e-3)" "unprognostic (2.17e-1)" "unprognostic (2.21e-3)" "unprognostic (1.51e-1)" "unprognostic (5.53e-2)" "unprognostic (4.99e-2)" "unprognostic (3.86e-2)" "prognostic favorable (2.00e-6)" "unprognostic (9.61e-2)" "unprognostic (7.18e-2)" "unprognostic (2.81e-1)" "unprognostic (7.30e-2)" 15.4 35.9 12.7 7.7 13.2 24.9 11.2 14.2 16.4 7.2 14.2 10.1 9.0 7.0 8.4 10.9 8.4 7.5 23.1 13.1 13.6 20.7 32.4 7.7 10.2 14.0 13.5 10.4 10.1 13.1 6.9 7.8 14.4 7.9 9.7 12.4 8.6 7.9 26.8 10.7 7.8 8.3 13.8 10.4 11.1 12.8 13.7 7.6 8.9 29.7 11.3 15.2 7.6 14.1 21.7 20.0 11.3 22.3 21.3 17.9 13.9 27.9 22.2 30.8 22.6 35.5 27.5 46.4 18.3 21.4 47.7 21.5 45.0 32.0 35.9 11.2 28.2 49.8 17.6 38.7 24.9 50.7 24.2 17.8 41.4 27.3 32.8 15.7 27.4 30.8 29.7 18.9 36.7 21.9 40.3 62.5 16.9 38.8 65.7 26.6 42.1 19.5 31.0 22.4 31.6 15.3 21.9 21.5 24.3 11.4 19.3 29.2 23.8 20.5 12.7 29.5 49.3 20.3 31.1 31.0 27.9 32.6 16.5 12.0 25.2 41.1 22.8 27.6 31.9 27.3 24.4 25.9 36.3 21.6 30.8 23.9 8.4 26.2 22.7 22.0 26.6 27.2 12.7 13.2 14.2 16.4 13.1 13.6 14.0 13.5 14.4 13.8 13.7 14.1 52.5 25.6 32.1 1.6 40.7 133.4 134.8 68.5 60.9 27.8 44.0 43.6 96.1 34.3 43.1 38.6 10.4 69.3 52.9 35.3 133.1 75.0 60.3 35.0 41.7 51.5 18.5 34.5 4.5 47.7 80.3 46.5 26.0 38.0 58.2 23.2 25.0 109.4 60.3 28.6 5.1 34.1 52.9 29.0 74.7 84.9 28.0 41.7 64.0 2.8 54.0 26.4 17.5 3.0 6.5 91.4 27.6 29.0 27.0 116.5 49.2 203.1 36.2 28.0 0.0 38.1 56.3 51.7 55.0 58.1 125.2 86.1 61.6 92.0 47.0 120.3 GRPEL2 "DKFZp451C205, FLJ23713, Mt-GrpE#2" ENSG00000164284 "GrpE like 2, mitochondrial" Q8TAA5 5 149345430-149354583 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 44.9" "Cell type enhanced" "Detected in many" "Endothelial cells: 36.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018173, HPA023211" Approved Enhanced Mitochondria NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Mitochondria "HPA018173: AB_1850358, HPA023211: AB_1850360" "unprognostic (3.13e-2)" "unprognostic (1.69e-1)" "prognostic favorable (3.87e-5)" "prognostic unfavorable (2.21e-4)" "unprognostic (3.22e-1)" "unprognostic (2.07e-2)" "prognostic unfavorable (6.16e-8)" "unprognostic (1.34e-1)" "unprognostic (8.16e-2)" "unprognostic (3.43e-2)" "unprognostic (2.21e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (4.20e-4)" "unprognostic (3.40e-1)" "unprognostic (1.79e-1)" "unprognostic (2.20e-1)" "unprognostic (2.26e-1)" 6.8 4.2 4.6 5.9 5.0 5.0 5.1 8.8 6.2 13.4 2.8 4.1 4.8 4.3 4.1 44.9 3.8 3.5 8.2 4.8 6.1 6.2 4.7 9.3 7.2 6.3 5.5 5.4 3.7 6.5 3.0 7.5 6.6 3.9 3.9 5.6 7.2 4.0 8.8 4.5 5.0 3.6 5.3 4.8 5.5 4.6 6.0 5.3 6.5 5.1 11.0 4.9 11.0 5.9 16.3 9.5 12.5 44.2 7.9 8.1 25.2 14.8 11.9 13.5 19.1 22.7 10.6 17.5 15.0 7.6 18.0 12.4 20.3 20.8 18.8 9.0 18.0 21.1 16.0 11.9 22.1 21.2 11.1 12.4 24.5 16.3 26.8 5.9 9.7 22.1 18.5 39.4 9.9 11.2 13.4 17.1 16.0 9.9 34.5 17.3 17.0 22.0 8.8 15.7 25.3 20.7 14.7 25.9 44.5 9.3 23.0 24.5 11.2 14.6 16.3 10.4 21.3 14.7 21.6 16.6 14.3 28.9 14.5 9.9 2.5 3.6 5.1 2.4 6.1 3.9 7.6 5.6 3.9 1.8 9.9 7.5 2.0 3.8 2.8 1.1 15.1 4.8 4.6 5.0 8.8 6.2 4.8 6.1 6.3 5.5 6.6 5.3 6.0 5.9 20.9 9.6 6.4 2.3 3.3 17.8 5.3 9.9 9.6 6.1 7.0 6.0 8.8 4.3 9.3 9.2 8.4 9.2 3.5 5.1 1.9 5.3 11.6 2.3 4.9 36.0 6.0 11.4 4.3 6.0 18.2 6.0 3.6 5.6 2.5 6.6 20.3 7.1 6.0 3.3 5.1 4.5 10.2 9.7 7.4 5.4 4.1 2.7 7.2 5.6 4.5 5.4 2.1 3.0 4.9 7.5 3.1 5.3 4.4 7.1 6.5 6.2 5.0 6.7 0.0 6.1 6.0 22.6 12.0 10.0 19.6 5.6 9.2 5.2 7.2 8.2 GRSF1 ENSG00000132463 "G-rich RNA sequence binding factor 1" Q12849 4 70815783-70839897 "Predicted intracellular proteins" "mRNA processing, tRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 275.2" "Cell type enhanced" "Detected in all" "monocytes: 301.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036984, HPA036985" Enhanced Enhanced Mitochondria NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 3: Monocytes - Immune response regulation" Mitochondria "HPA036984: AB_2675415, HPA036985: AB_10672785" "unprognostic (1.45e-3)" "unprognostic (1.82e-2)" "prognostic favorable (1.47e-5)" "unprognostic (8.63e-2)" "unprognostic (6.73e-2)" "unprognostic (4.15e-3)" "prognostic unfavorable (8.29e-5)" "unprognostic (1.94e-1)" "unprognostic (1.43e-1)" "unprognostic (1.66e-2)" "unprognostic (7.68e-2)" "unprognostic (8.05e-2)" "prognostic favorable (2.72e-9)" "unprognostic (6.12e-2)" "unprognostic (1.23e-1)" "unprognostic (1.78e-1)" "unprognostic (9.65e-3)" 38.0 61.2 38.4 36.9 37.7 23.7 37.7 42.5 47.1 36.3 58.9 54.6 43.1 32.5 34.0 42.0 43.0 35.2 80.7 41.0 44.5 55.8 54.4 35.5 47.4 40.3 42.3 38.4 62.0 48.8 21.5 43.8 41.6 39.9 62.7 25.4 83.9 35.3 275.2 32.0 41.3 40.0 40.7 34.6 50.8 32.8 40.9 76.0 45.7 155.0 53.7 50.3 25.8 46.1 116.9 78.1 90.0 94.5 93.5 108.1 128.3 138.2 87.3 102.3 83.5 80.5 117.1 167.6 102.9 143.7 53.0 43.4 161.3 108.6 135.9 91.3 52.8 88.4 75.2 112.4 115.1 130.8 48.7 91.9 102.2 103.6 71.6 123.0 106.9 91.9 102.6 94.7 144.2 124.9 217.4 92.0 96.3 127.1 80.9 88.2 139.8 71.6 126.1 144.0 93.4 84.0 65.3 183.6 234.3 104.7 79.8 63.3 98.4 95.1 99.7 79.4 88.7 78.1 66.2 106.4 78.6 83.6 94.5 12.7 17.4 7.7 10.1 12.3 12.2 7.4 14.6 15.5 28.1 6.1 14.4 12.6 2.0 20.0 15.2 27.2 13.3 8.4 38.4 37.7 42.5 47.1 41.0 44.5 40.3 42.3 41.6 40.7 40.9 46.1 27.8 32.1 36.6 19.6 38.0 50.0 53.7 32.9 48.3 18.2 37.7 28.3 135.5 40.0 30.4 27.6 25.0 106.2 57.4 52.9 74.3 70.3 7.6 53.8 40.4 33.0 69.0 41.2 35.1 61.3 141.3 41.2 65.2 44.5 17.2 60.2 35.0 50.9 63.2 28.6 30.5 73.5 36.7 66.3 53.7 6.7 34.8 45.4 62.2 24.4 301.5 23.8 41.2 21.6 28.0 60.1 46.7 39.1 58.7 65.9 47.1 74.1 27.6 19.6 19.7 38.4 46.2 35.0 61.8 69.7 50.4 77.2 45.1 99.0 89.3 67.0 GSDMC MLZE ENSG00000147697 "Gasdermin C" Q9BYG8 8 129748196-129786624 "Predicted intracellular proteins, Transporters" Necrosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 33.1;lymphoid tissue: 12.8;skin 1: 25.5;vagina: 11.4" "Group enriched" "Detected in some" 4 "Basal keratinocytes: 46.5;Basal squamous epithelial cells: 37.5;Squamous epithelial cells: 29.5;Suprabasal keratinocytes: 53.1" "Cancer enhanced" "Detected in many" "cervical cancer: 11.8;head and neck cancer: 19.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 5.2;HaCaT: 3.7;hTCEpi: 1.8;HUVEC TERT2: 2.0;TIME: 5.8" "Low region specificity" "Detected in many" "HPA023670, HPA024767, HPA026317" Supported Approved Mitochondria NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Mitochondria "HPA023670: AB_1854006, HPA024767: AB_1854007, HPA026317: AB_1854008" "unprognostic (6.33e-3)" "unprognostic (1.49e-1)" "unprognostic (2.61e-3)" "unprognostic (4.23e-2)" "unprognostic (2.11e-2)" "unprognostic (4.22e-3)" "unprognostic (1.43e-2)" "unprognostic (1.15e-1)" "unprognostic (8.28e-2)" "unprognostic (7.51e-2)" "unprognostic (4.92e-3)" "unprognostic (5.71e-2)" "unprognostic (2.93e-3)" "unprognostic (1.87e-2)" "unprognostic (1.88e-1)" "unprognostic (8.66e-2)" "unprognostic (1.90e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 4.4 0.0 0.0 0.0 0.0 0.1 33.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 5.4 0.0 0.0 25.5 0.0 0.0 0.0 12.8 0.0 0.0 0.0 0.0 0.0 0.0 4.0 2.4 11.4 0.1 5.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.7 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 2.0 1.0 0.0 46.5 0.9 7.4 37.5 0.0 1.5 0.9 3.6 0.0 9.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.2 0.2 0.0 0.9 0.0 0.0 0.1 0.2 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 6.1 0.0 3.9 0.0 0.0 0.2 7.2 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.0 0.4 0.0 0.0 1.3 0.0 0.0 0.1 0.5 0.0 0.1 29.5 53.1 0.0 0.1 0.0 0.0 2.8 GTPBP3 "FLJ14700, GTPBG3, MSS1, MTGP1, THDF1" ENSG00000130299 "GTP binding protein 3, mitochondrial" Q969Y2 19 17334920-17342731 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "tRNA processing" "Cardiomyopathy, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042158 Approved Supported Mitochondria NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 32: Non-specific - Translation" Mitochondria "HPA042158: AB_10964400" "unprognostic (1.52e-1)" "unprognostic (1.08e-2)" "unprognostic (2.23e-1)" "unprognostic (3.08e-3)" "unprognostic (1.34e-1)" "unprognostic (2.18e-2)" "prognostic unfavorable (1.86e-4)" "unprognostic (6.32e-2)" "unprognostic (1.82e-1)" "unprognostic (2.70e-2)" "unprognostic (3.25e-2)" "prognostic unfavorable (2.81e-4)" "prognostic unfavorable (1.64e-4)" "unprognostic (4.94e-3)" "unprognostic (1.21e-1)" "unprognostic (2.56e-1)" "unprognostic (1.79e-1)" 8.0 13.5 6.8 5.1 5.9 4.9 9.1 6.1 7.0 10.6 6.0 8.8 5.5 8.5 1.8 13.1 9.6 2.1 8.7 6.3 7.5 11.3 14.1 7.6 6.5 9.0 7.1 10.2 12.2 5.3 8.8 3.3 9.0 10.5 2.9 4.1 10.2 3.9 9.2 15.1 9.4 2.8 6.2 12.7 9.3 3.0 7.0 3.5 8.8 3.1 4.3 8.9 10.4 6.5 19.7 11.6 10.6 13.8 3.5 3.3 51.2 9.1 3.8 8.2 8.0 16.2 15.6 29.8 22.8 3.4 5.8 17.2 13.5 7.8 6.7 24.9 62.6 17.8 18.4 21.4 4.6 19.3 11.2 3.4 11.2 7.6 9.7 5.7 6.6 20.9 34.6 13.0 4.2 15.7 23.2 17.2 22.4 12.2 51.5 27.4 8.2 28.3 7.6 8.8 24.7 22.0 9.8 14.9 12.9 7.0 13.2 7.9 7.2 12.6 11.3 28.0 16.3 21.9 36.7 35.4 10.0 25.0 9.8 0.4 2.3 0.4 4.8 3.2 4.0 3.0 4.5 4.3 3.6 4.1 4.9 4.6 0.7 5.2 1.7 6.7 3.3 2.8 6.8 5.9 6.1 7.0 6.3 7.5 9.0 7.1 9.0 6.2 7.0 6.5 10.5 3.2 5.3 11.8 10.8 17.1 9.3 11.4 13.6 20.3 14.9 14.9 7.2 4.3 6.1 5.5 31.3 21.4 10.2 5.9 7.9 12.5 0.3 5.2 7.7 9.7 3.0 12.0 6.2 10.9 25.3 9.0 9.2 7.9 2.5 15.7 8.6 9.8 10.1 11.8 9.4 9.7 12.2 5.6 7.7 0.2 11.8 6.2 10.6 2.8 8.6 8.3 12.3 8.0 8.3 10.8 7.5 13.5 18.0 9.7 9.1 7.1 5.9 20.7 6.6 7.2 10.8 2.9 4.6 11.5 17.5 8.3 12.6 15.9 13.2 6.4 GTPBP8 HSPC135 ENSG00000163607 "GTP binding protein 8 (putative)" Q8N3Z3 3 112990984-113015060 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 79.8;Spermatocytes: 79.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034831, HPA058631" Approved Enhanced Mitochondria No No "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 36: HEL - Hemostasis" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "HPA034831: AB_10671506, HPA058631: AB_2683783" "unprognostic (1.98e-1)" "unprognostic (1.02e-2)" "unprognostic (4.36e-2)" "unprognostic (1.99e-3)" "unprognostic (4.39e-2)" "unprognostic (2.00e-2)" "unprognostic (7.18e-3)" "unprognostic (1.80e-2)" "unprognostic (1.06e-2)" "unprognostic (2.08e-1)" "unprognostic (1.35e-2)" "unprognostic (1.21e-2)" "prognostic favorable (3.07e-5)" "unprognostic (7.10e-2)" "unprognostic (7.21e-2)" "unprognostic (4.57e-1)" "unprognostic (2.69e-1)" 5.3 5.7 3.6 6.1 4.3 8.4 5.6 4.6 4.9 4.6 4.6 6.0 6.6 5.6 3.7 7.4 4.4 5.2 11.9 3.9 3.9 7.3 5.9 4.3 11.2 4.3 3.8 6.7 6.8 8.9 4.5 6.1 4.2 5.7 7.1 4.2 6.5 3.7 20.0 4.8 6.0 5.5 4.4 4.9 7.5 14.4 3.9 9.7 10.1 18.3 8.1 5.9 4.7 6.4 25.5 10.8 15.7 16.5 9.2 15.6 11.5 17.9 14.7 17.0 20.5 18.6 10.4 16.8 9.7 10.0 14.2 17.1 21.0 17.1 23.5 7.0 13.4 46.5 11.4 11.6 8.4 28.9 10.5 11.9 11.9 9.6 7.0 19.2 16.1 19.9 16.4 19.5 18.0 8.8 18.5 14.4 32.8 13.2 20.8 16.1 14.7 10.4 14.4 16.3 17.5 18.2 14.2 11.3 25.7 13.7 12.3 19.6 9.8 12.7 19.4 4.5 16.0 13.1 17.4 24.0 12.7 23.6 14.0 7.9 4.3 2.9 6.4 3.0 5.7 4.2 7.8 6.3 8.1 3.6 9.9 6.5 0.7 8.7 2.7 3.7 5.4 4.5 3.6 4.3 4.6 4.9 3.9 3.9 4.3 3.8 4.2 4.4 3.9 6.4 13.1 16.0 15.4 2.9 16.9 13.5 15.9 28.8 8.0 11.5 12.9 12.4 25.8 10.0 19.5 5.5 6.2 28.3 27.1 10.4 23.5 16.3 79.8 17.7 12.9 11.6 10.2 22.7 5.5 18.3 25.1 13.3 12.8 18.3 19.7 20.0 17.9 7.7 22.7 10.1 6.3 10.3 28.5 16.7 14.8 35.5 11.8 13.6 10.6 4.7 18.3 10.4 13.4 7.1 6.9 16.5 12.2 5.7 17.1 12.8 17.7 29.6 16.0 14.0 0.0 17.4 15.8 79.7 28.1 16.1 12.1 15.2 22.5 34.9 12.0 18.9 HADH "HADH1, HADHSC, SCHAD" ENSG00000138796 "Hydroxyacyl-CoA dehydrogenase" Q16836 4 107989714-108035174 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Oxidoreductase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 280.3" "Cell type enhanced" "Detected in all" "Hepatocytes: 272.4;Proximal enterocytes: 383.0;Proximal tubular cells: 318.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039588, HPA043888" Enhanced Supported Mitochondria No Yes 1000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA039588: AB_10673425, HPA043888: AB_2678716" "unprognostic (1.73e-1)" "unprognostic (3.32e-3)" "unprognostic (3.05e-3)" "unprognostic (8.86e-3)" "unprognostic (1.83e-1)" "unprognostic (6.83e-2)" "unprognostic (9.26e-3)" "unprognostic (1.55e-2)" "unprognostic (9.22e-2)" "unprognostic (3.24e-2)" "unprognostic (2.96e-1)" "unprognostic (1.18e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.67e-1)" "unprognostic (4.22e-2)" "unprognostic (5.67e-2)" "unprognostic (1.88e-2)" 143.0 54.1 23.2 20.9 23.8 27.4 74.9 24.6 26.3 37.9 33.5 101.2 84.4 49.8 24.9 34.2 56.2 24.0 175.6 22.9 27.2 140.2 225.5 22.8 22.2 24.7 26.3 54.3 42.1 40.2 18.0 13.7 26.0 35.4 90.8 10.4 55.9 42.4 249.7 28.0 89.1 72.7 26.0 18.0 60.7 27.9 24.9 76.0 37.7 280.3 28.5 34.1 28.7 28.0 32.2 27.9 64.3 46.2 149.2 48.2 27.0 43.1 68.5 49.6 48.9 21.2 60.9 185.0 23.5 38.8 34.6 42.0 85.5 64.5 55.5 49.6 37.2 39.9 50.5 48.9 24.3 88.2 17.0 50.4 34.1 35.1 32.3 41.4 34.4 127.1 53.1 98.7 57.3 58.9 163.6 36.7 29.0 147.8 30.1 113.5 84.3 89.2 54.5 129.4 73.2 43.1 41.1 161.9 45.6 37.0 77.4 70.8 20.6 35.5 18.9 48.5 26.7 52.1 63.3 80.6 47.0 60.2 27.0 0.0 11.1 11.4 17.2 14.2 22.1 31.4 19.5 20.7 36.8 27.1 22.4 22.2 1.2 36.7 20.1 41.7 17.7 16.3 23.2 23.8 24.6 26.3 22.9 27.2 24.7 26.3 26.0 26.0 24.9 28.0 17.3 28.9 33.8 11.1 25.7 15.6 54.2 65.8 41.5 6.9 46.5 56.1 225.6 52.9 48.1 35.0 4.2 41.0 18.3 164.7 160.4 43.3 196.8 41.4 22.6 17.5 32.4 65.6 15.1 32.2 44.7 28.2 52.5 26.1 10.8 63.9 21.0 272.4 116.5 6.7 18.9 93.3 36.7 37.8 11.8 108.5 46.3 25.3 21.4 12.2 15.3 26.8 8.2 9.5 9.9 23.0 100.8 35.3 32.0 33.9 383.0 318.8 70.8 6.8 39.5 21.7 38.2 22.4 20.3 64.0 18.2 17.0 19.6 66.3 194.2 49.1 HADHA "GBP, LCEH, LCHAD, MTPA" ENSG00000084754 "Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha" P40939 2 26190635-26244672 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Lyase, Multifunctional enzyme, Oxidoreductase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 502.5" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 527.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015536, HPA056070" Approved Enhanced Mitochondria NA NA 470000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" Mitochondria "HPA015536: AB_1850473, HPA056070: AB_2683026" "unprognostic (2.02e-1)" "unprognostic (1.38e-2)" "unprognostic (2.55e-1)" "unprognostic (3.43e-1)" "unprognostic (2.67e-2)" "unprognostic (3.23e-2)" "unprognostic (1.25e-2)" "unprognostic (2.02e-1)" "unprognostic (5.16e-2)" "unprognostic (3.45e-1)" "unprognostic (3.81e-1)" "unprognostic (1.16e-1)" "prognostic favorable (3.68e-5)" "unprognostic (7.97e-2)" "unprognostic (1.71e-1)" "unprognostic (2.87e-3)" "unprognostic (2.64e-2)" 105.0 125.3 57.7 31.1 60.7 46.3 94.9 65.0 69.6 72.6 59.1 108.4 115.0 61.8 30.7 90.1 60.1 32.4 330.2 52.8 61.9 99.0 156.7 66.9 35.3 64.4 62.2 77.8 101.4 95.0 57.4 39.2 64.2 60.2 76.1 14.9 77.9 33.4 502.5 95.7 106.2 57.4 61.8 68.4 93.8 49.0 62.4 46.7 59.5 300.7 58.5 79.1 73.6 67.2 105.7 88.1 58.4 90.8 221.1 139.9 51.5 80.6 84.7 78.5 67.7 114.7 104.1 71.7 50.2 138.4 78.6 66.8 103.4 152.6 72.5 139.1 103.6 103.3 86.2 197.9 73.3 132.2 69.2 142.7 101.6 112.4 109.3 82.8 127.7 70.4 140.2 133.2 101.1 128.2 63.4 137.7 50.1 77.5 134.1 52.9 128.5 143.7 90.3 125.3 41.9 85.1 94.6 104.6 102.4 44.5 52.2 125.8 127.1 48.8 70.7 69.9 58.0 44.8 86.5 113.4 77.6 150.2 56.2 22.5 84.0 33.5 31.8 92.3 39.1 40.5 36.8 38.7 80.8 31.2 42.6 40.1 20.9 38.8 86.1 31.3 50.9 89.9 57.7 60.7 65.0 69.6 52.8 61.9 64.4 62.2 64.2 61.8 62.4 67.2 122.4 89.8 99.0 47.0 101.2 89.0 137.5 139.9 97.3 35.6 89.7 96.4 349.9 82.9 128.0 77.3 52.1 182.0 95.1 242.1 131.0 120.8 39.2 73.3 121.1 99.1 91.4 155.9 22.8 108.5 94.7 96.1 100.4 85.5 139.9 140.3 84.3 185.1 163.0 20.2 28.2 156.5 89.5 136.8 106.0 74.3 92.6 145.0 81.8 12.2 170.7 65.4 93.7 30.7 37.4 90.0 195.6 84.2 90.4 76.2 527.4 182.5 84.8 62.3 52.6 129.9 109.6 147.9 54.9 136.5 103.3 129.2 100.5 154.7 216.7 104.4 HADHB MTPB ENSG00000138029 "Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta" P55084 2 26243170-26290465 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 793.3;skeletal muscle: 950.6;tongue: 1097.1" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1167.5;Distal tubular cells: 520.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037539, HPA037540, HPA066099" Enhanced Supported Mitochondria No No 61000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA037539: AB_10671374, HPA037540: AB_2675531, HPA066099: AB_2685618" "unprognostic (5.15e-2)" "unprognostic (8.72e-2)" "unprognostic (8.21e-2)" "unprognostic (8.67e-2)" "unprognostic (7.70e-2)" "unprognostic (2.59e-2)" "unprognostic (7.29e-2)" "unprognostic (9.70e-2)" "unprognostic (2.01e-1)" "unprognostic (2.09e-1)" "unprognostic (2.03e-1)" "unprognostic (8.94e-2)" "prognostic favorable (1.37e-9)" "unprognostic (2.47e-1)" "unprognostic (2.50e-1)" "unprognostic (2.88e-1)" "unprognostic (9.68e-2)" 127.0 224.7 120.6 51.1 135.4 58.8 91.3 146.4 138.1 65.2 128.0 110.7 224.2 55.9 73.7 101.3 68.8 64.3 793.3 109.0 138.1 231.4 324.8 64.7 54.9 135.9 141.6 78.4 83.7 209.5 48.1 65.6 139.6 77.1 113.2 63.0 104.8 75.0 950.6 74.4 184.4 79.0 141.4 75.8 109.0 67.1 143.3 53.1 90.8 1097.1 62.5 89.2 64.1 152.8 108.2 83.2 56.6 102.2 342.1 190.1 57.9 89.0 134.6 89.0 86.8 100.5 101.7 53.9 60.8 145.3 100.1 82.8 95.2 124.8 109.2 121.1 83.1 123.6 44.9 194.2 145.9 100.6 90.0 183.7 201.6 92.7 149.0 151.0 168.2 81.0 105.2 83.9 189.5 78.0 57.1 190.7 39.8 160.2 89.0 61.7 188.3 103.2 183.3 148.9 27.2 93.7 151.7 169.8 239.5 68.5 105.4 177.9 118.0 83.5 86.9 79.3 65.1 62.6 101.1 94.7 95.5 158.4 84.4 95.7 168.1 66.4 45.2 150.3 57.6 65.5 61.3 56.6 154.2 49.7 55.8 51.3 72.7 88.2 123.3 51.8 94.7 135.6 120.6 135.4 146.4 138.1 109.0 138.1 135.9 141.6 139.6 141.4 143.3 152.8 106.5 48.1 36.5 63.0 48.3 62.1 136.5 183.3 49.5 29.3 49.5 52.3 1167.5 104.4 107.7 97.5 56.3 227.9 42.4 129.5 520.4 124.0 93.4 59.5 49.0 75.2 74.9 85.2 32.7 57.2 75.2 79.5 53.0 60.2 62.8 94.2 69.9 277.6 139.6 13.5 33.0 93.4 114.0 98.1 67.4 99.7 56.5 78.1 88.9 27.2 110.2 65.0 32.0 35.2 47.5 58.4 134.8 62.8 37.1 60.5 376.0 321.1 73.5 80.0 72.3 72.9 80.7 120.4 49.4 53.8 54.7 186.6 45.2 194.0 113.5 110.3 HARS2 "HARSL, HARSR, HO3" ENSG00000112855 "Histidyl-tRNA synthetase 2, mitochondrial" P49590 5 140691430-140699305 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035941, HPA075303" Approved Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 39: CACO-2 - Unknown function" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA035941: AB_10671237, HPA075303: " "prognostic unfavorable (6.49e-4)" "unprognostic (3.15e-2)" "prognostic favorable (6.19e-4)" "unprognostic (1.79e-2)" "unprognostic (1.78e-1)" "unprognostic (8.30e-3)" "prognostic unfavorable (2.92e-4)" "unprognostic (7.77e-2)" "unprognostic (1.88e-1)" "unprognostic (5.26e-2)" "unprognostic (1.58e-1)" "unprognostic (2.68e-2)" "unprognostic (1.85e-1)" "unprognostic (5.40e-2)" "unprognostic (1.51e-1)" "unprognostic (2.49e-1)" "unprognostic (1.31e-2)" 19.6 24.6 14.0 13.8 14.2 14.4 18.9 13.7 14.2 22.0 16.8 23.5 16.6 19.5 15.0 20.0 18.4 9.8 27.9 14.0 14.2 23.3 19.3 16.0 15.1 14.1 14.0 21.1 15.6 20.8 20.8 14.2 14.4 20.2 22.3 11.5 17.5 13.4 35.0 21.1 20.9 14.0 13.8 26.9 20.4 14.8 14.3 15.2 19.0 28.4 16.1 21.1 20.6 15.7 20.9 46.2 19.6 50.6 21.9 28.6 32.3 26.3 29.8 36.1 31.4 42.7 25.5 26.3 41.3 29.3 35.5 25.9 27.3 49.4 33.2 26.6 22.4 19.1 45.3 28.6 20.9 26.1 27.1 27.0 32.9 35.3 39.7 29.4 26.5 27.4 18.0 24.1 35.6 26.6 25.7 32.1 22.6 15.7 28.9 25.8 19.9 26.8 33.9 48.1 27.0 38.9 38.1 61.0 54.2 28.5 54.0 25.5 32.5 32.4 17.8 18.2 35.2 23.6 37.0 25.2 25.4 29.5 32.9 37.7 13.1 28.6 19.1 18.9 21.1 16.9 18.4 19.2 14.9 14.8 19.0 20.6 15.1 29.3 15.0 12.1 20.1 13.3 14.0 14.2 13.7 14.2 14.0 14.2 14.1 14.0 14.4 13.8 14.3 15.7 8.6 3.2 5.8 2.6 12.3 3.4 3.7 7.8 9.6 5.5 5.9 5.5 20.4 7.2 7.8 5.5 0.0 20.3 6.6 8.5 13.7 14.9 1.1 5.3 8.0 9.7 7.7 9.9 5.5 16.1 18.7 6.3 13.3 6.4 2.5 11.8 9.7 7.2 10.0 0.0 4.8 8.7 18.3 8.2 6.2 2.3 9.3 7.4 3.6 2.8 12.8 8.3 3.1 6.0 6.2 18.3 12.1 10.5 9.6 4.1 7.2 9.0 8.6 5.6 0.0 4.4 7.0 8.9 14.4 9.5 4.0 14.4 8.0 11.2 11.7 4.4 HAX1 "HAX-1, HCLSBP1, HS1BP1" ENSG00000143575 "HCLS1 associated protein X-1" O00165 1 154272589-154275875 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055141, HPA075289" Approved Supported Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA055141: AB_2682714, HPA075289: AB_2686742" "unprognostic (1.32e-1)" "unprognostic (2.68e-1)" "unprognostic (9.50e-2)" "unprognostic (6.93e-2)" "unprognostic (2.88e-2)" "unprognostic (1.73e-2)" "unprognostic (1.55e-3)" "unprognostic (2.34e-1)" "unprognostic (2.20e-1)" "unprognostic (9.09e-3)" "unprognostic (3.09e-2)" "unprognostic (8.91e-2)" "prognostic unfavorable (1.34e-5)" "unprognostic (1.52e-1)" "unprognostic (1.59e-1)" "unprognostic (1.69e-1)" "unprognostic (3.96e-1)" 58.6 63.0 100.0 43.6 105.5 36.8 74.4 105.2 124.1 60.0 100.6 62.0 48.0 46.2 100.1 53.7 61.7 40.4 168.6 100.5 107.9 76.1 104.0 45.2 58.3 102.1 99.9 72.9 85.5 84.9 88.6 40.5 102.9 55.5 63.3 54.1 85.8 63.8 256.7 48.8 43.2 64.1 105.1 47.1 66.3 69.5 105.0 67.4 69.2 242.7 77.3 58.5 48.9 103.3 115.3 100.7 84.2 178.0 100.3 111.8 132.1 109.8 178.7 227.0 207.5 126.6 125.7 170.9 150.7 188.0 105.9 100.0 190.7 151.3 172.3 171.0 140.8 81.8 76.5 104.4 221.5 172.5 167.0 104.4 274.2 172.8 206.3 82.2 129.7 246.1 166.1 244.8 145.6 260.9 169.9 136.1 88.7 277.4 213.2 121.3 59.7 326.7 115.4 60.8 123.2 121.7 96.4 228.2 326.7 137.5 190.0 454.8 64.5 92.7 122.7 97.7 148.8 284.8 315.9 315.3 139.0 158.4 153.4 266.5 97.6 215.4 113.7 121.9 129.3 136.1 139.2 128.3 118.6 142.2 166.5 132.6 61.1 116.7 150.1 122.8 183.3 163.9 100.0 105.5 105.2 124.1 100.5 107.9 102.1 99.9 102.9 105.1 105.0 103.3 69.9 28.9 37.6 7.2 125.2 74.6 112.2 118.8 60.9 57.0 92.8 123.1 106.9 62.9 71.6 46.0 47.9 84.8 76.1 54.1 181.9 93.3 147.6 41.3 36.6 65.6 57.6 66.0 12.0 106.4 132.1 62.2 36.7 34.0 99.6 80.6 61.4 90.3 98.7 40.4 12.9 67.1 91.6 63.9 79.3 104.6 61.2 66.8 87.2 9.4 128.5 91.1 91.6 7.5 17.1 84.6 63.6 62.1 192.9 92.5 128.7 141.8 59.3 97.5 59.2 58.2 76.0 223.8 112.0 71.0 76.4 88.8 97.7 74.3 71.7 101.7 HCCS "CCHL, MLS" ENSG00000004961 "Holocytochrome c synthase" P53701 X 11111301-11123086 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Lyase "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002946 Approved Enhanced Mitochondria "Intracellular and membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" Mitochondria "HPA002946: AB_1079041" "prognostic unfavorable (8.69e-5)" "unprognostic (6.89e-3)" "unprognostic (8.46e-3)" "unprognostic (4.92e-2)" "unprognostic (1.34e-1)" "unprognostic (5.44e-2)" "prognostic unfavorable (1.35e-5)" "unprognostic (9.18e-2)" "unprognostic (2.73e-1)" "unprognostic (2.52e-2)" "unprognostic (2.10e-2)" "unprognostic (1.60e-1)" "prognostic favorable (6.17e-8)" "unprognostic (2.66e-2)" "unprognostic (1.52e-1)" "unprognostic (2.04e-1)" "unprognostic (1.93e-2)" 13.9 16.1 6.2 13.7 6.7 20.5 12.6 7.0 8.4 8.4 8.4 21.6 23.1 9.6 7.6 19.3 8.5 10.8 39.0 7.4 6.8 17.6 22.9 11.5 15.6 6.7 6.2 8.3 9.9 25.1 8.3 13.1 6.4 9.5 21.6 13.5 15.2 10.0 64.4 17.6 20.2 12.5 6.2 14.5 15.3 10.2 6.7 13.0 10.8 57.0 17.1 22.3 11.6 6.1 54.3 60.5 31.8 28.5 25.6 25.2 29.2 52.0 43.0 67.8 57.5 70.7 38.5 34.3 26.3 46.1 80.8 49.8 63.2 51.8 70.5 30.8 48.0 34.1 80.8 38.6 47.3 40.9 39.4 24.2 37.4 67.9 46.5 37.9 49.1 26.1 63.1 41.1 46.3 72.5 28.0 31.4 51.5 36.6 70.1 27.3 59.9 65.4 44.0 44.8 20.9 24.2 54.8 58.7 38.2 66.7 45.6 27.1 48.7 42.4 23.6 110.4 47.0 26.9 29.0 47.8 35.5 28.8 42.7 25.6 47.8 30.1 20.2 66.4 19.0 39.0 19.6 18.2 62.2 34.7 17.1 22.1 13.1 19.1 57.4 56.2 23.5 19.0 6.2 6.7 7.0 8.4 7.4 6.8 6.7 6.2 6.4 6.2 6.7 6.1 15.5 6.4 4.8 2.3 20.8 54.8 53.2 57.0 22.8 5.3 16.1 13.7 49.3 17.2 33.3 16.5 0.0 32.9 12.4 44.6 50.9 34.9 13.7 19.0 10.4 21.0 10.8 32.8 3.8 29.3 37.9 17.1 12.8 16.7 13.3 10.4 15.7 18.5 41.8 8.4 4.5 19.2 67.1 21.0 44.1 2.3 13.4 23.5 24.9 1.9 27.9 13.0 7.2 2.0 2.7 68.4 31.9 10.5 18.4 63.5 46.4 36.0 28.9 7.1 6.6 12.5 20.1 24.4 28.4 21.8 46.0 40.9 12.0 15.6 30.2 88.6 HDHD5 CECR5 ENSG00000069998 "Haloacid dehalogenase like hydrolase domain containing 5" Q9BXW7 22 17137511-17165287 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 43.0;Ductal cells: 35.2;Extravillous trophoblasts: 42.2;Granulosa cells: 37.0;Hofbauer cells: 42.3;Proximal tubular cells: 41.1;Theca cells: 55.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005548 Approved Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA005548: AB_1078497" "unprognostic (4.04e-2)" "unprognostic (5.04e-2)" "unprognostic (4.54e-3)" "unprognostic (6.61e-2)" "unprognostic (1.20e-1)" "unprognostic (5.71e-2)" "unprognostic (1.04e-3)" "unprognostic (7.35e-2)" "unprognostic (1.70e-1)" "unprognostic (4.98e-2)" "unprognostic (5.76e-2)" "unprognostic (2.35e-1)" "unprognostic (1.10e-1)" "unprognostic (7.07e-3)" "unprognostic (1.71e-1)" "unprognostic (1.20e-2)" "unprognostic (7.21e-3)" 17.4 29.7 15.0 13.2 15.3 16.5 17.3 15.4 15.7 12.9 16.7 21.5 26.5 14.6 6.8 21.7 13.6 9.8 45.0 15.4 14.8 19.8 40.5 12.6 14.5 15.4 14.9 12.2 20.9 17.5 11.6 8.1 14.6 15.5 14.1 5.7 18.6 10.0 46.9 23.0 17.2 11.4 14.8 19.3 19.9 15.9 15.9 13.6 10.1 55.7 12.0 16.5 14.1 15.0 64.0 41.5 30.5 41.5 17.7 10.8 38.8 17.9 19.6 47.1 50.2 61.1 23.3 103.9 29.3 21.6 23.0 44.0 38.7 42.0 21.8 31.6 56.7 0.0 30.7 0.0 29.4 47.6 23.5 26.1 51.1 21.0 23.1 26.4 33.3 67.4 31.0 26.2 24.9 62.1 84.2 97.2 46.6 97.9 36.7 47.4 45.8 26.3 32.2 34.7 61.4 46.5 34.9 49.9 54.3 23.9 50.1 58.5 29.1 39.7 29.4 28.2 31.3 41.3 48.5 77.8 32.0 0.1 34.2 12.3 86.2 4.7 28.4 56.7 35.6 24.6 26.4 25.8 74.5 23.6 34.3 29.3 4.5 30.7 31.4 30.9 29.7 48.0 15.0 15.3 15.4 15.7 15.4 14.8 15.4 14.9 14.6 14.8 15.9 15.0 21.5 6.4 2.8 0.0 3.6 0.0 0.0 0.0 0.0 0.0 23.9 22.4 0.0 0.0 5.0 5.5 0.0 26.5 9.3 0.0 43.0 35.2 0.0 8.4 14.9 9.2 0.0 0.0 0.0 28.2 42.2 7.7 0.0 11.5 5.1 37.0 0.0 0.0 42.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 5.2 0.0 0.0 0.0 0.0 22.9 0.0 0.0 0.5 0.0 0.0 41.1 1.5 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 15.7 3.4 55.8 0.0 0.0 HEATR6 "ABC1, FLJ22087" ENSG00000068097 "HEAT repeat containing 6" Q6AI08 17 60041008-60078922 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 64.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030789, HPA062157" Uncertain Approved Mitochondria NA NA "Cluster 37: B-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA030789: AB_10601660, HPA062157: AB_2684700" "unprognostic (1.98e-1)" "unprognostic (7.95e-2)" "unprognostic (4.32e-1)" "prognostic unfavorable (2.03e-4)" "unprognostic (4.22e-1)" "unprognostic (1.00e-1)" "prognostic unfavorable (5.02e-6)" "unprognostic (2.24e-1)" "unprognostic (2.86e-1)" "unprognostic (1.97e-1)" "unprognostic (6.81e-3)" "unprognostic (9.84e-2)" "prognostic unfavorable (6.73e-4)" "unprognostic (5.01e-2)" "unprognostic (1.81e-1)" "unprognostic (5.50e-2)" "unprognostic (2.11e-1)" 4.5 7.2 5.3 2.1 6.0 3.1 4.3 6.8 5.9 6.7 4.4 7.4 1.8 7.1 3.2 4.6 6.6 1.9 5.1 5.1 5.3 4.1 3.6 5.0 3.0 6.2 5.4 7.7 5.1 3.4 7.3 2.7 6.2 5.7 2.3 5.2 5.2 3.5 6.0 5.5 6.1 2.7 5.4 7.2 4.9 4.9 5.8 3.0 4.6 2.4 2.2 6.5 5.2 7.8 4.8 13.0 9.5 7.5 5.1 9.1 6.9 4.5 8.9 8.8 9.7 5.2 3.6 1.8 7.8 8.0 7.1 4.9 5.6 6.0 11.9 4.1 7.2 9.3 8.8 9.7 5.6 7.0 10.1 7.1 8.8 6.4 7.6 9.5 4.7 6.0 5.9 5.1 6.6 64.6 8.9 3.6 5.9 3.9 8.7 3.2 16.9 5.8 5.7 7.1 5.4 13.7 4.6 1.6 6.6 8.2 7.9 5.6 4.5 8.9 15.0 8.2 8.4 6.5 7.1 0.1 7.6 5.1 6.9 2.4 3.4 3.4 3.4 5.4 3.2 8.2 2.5 2.5 6.0 4.3 3.3 2.6 0.5 3.0 5.6 2.9 2.9 2.7 5.3 6.0 6.8 5.9 5.1 5.3 6.2 5.4 6.2 5.4 5.8 7.8 4.6 12.8 6.3 9.4 8.0 0.9 2.8 6.2 6.2 11.1 3.1 5.0 9.2 2.8 8.1 7.3 10.4 5.7 5.0 1.1 3.9 4.8 1.0 4.8 9.1 5.1 6.7 3.0 13.1 3.3 3.4 7.4 6.6 4.3 11.4 8.8 4.2 2.8 4.6 6.7 13.7 1.5 4.1 5.6 2.6 0.7 3.4 8.5 1.8 15.9 15.3 8.8 7.2 16.6 25.3 2.9 1.0 11.3 3.3 1.7 1.5 3.3 10.5 6.6 6.6 6.5 15.4 5.1 7.7 3.6 2.3 2.1 7.6 10.1 3.1 1.2 HIBCH ENSG00000198130 "3-hydroxyisobutyryl-CoA hydrolase" Q6NVY1 2 190189735-190344193 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Branched-chain amino acid catabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 230.2;Proximal tubular cells: 376.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036540, HPA036541, HPA067080" Enhanced Enhanced Mitochondria NA NA 74000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 7: Kidney - Transmembrane transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA036540: AB_10673355, HPA036541: AB_2675182, HPA067080: " "unprognostic (3.60e-3)" "unprognostic (3.88e-2)" "unprognostic (6.81e-2)" "unprognostic (2.36e-3)" "unprognostic (3.38e-1)" "unprognostic (2.78e-3)" "unprognostic (1.96e-1)" "unprognostic (1.89e-1)" "unprognostic (2.88e-1)" "prognostic favorable (1.22e-4)" "unprognostic (7.32e-2)" "unprognostic (1.37e-2)" "prognostic favorable (1.04e-10)" "unprognostic (1.34e-1)" "unprognostic (3.73e-1)" "unprognostic (1.36e-1)" "unprognostic (4.18e-3)" 34.0 60.1 40.6 17.4 49.2 14.5 28.5 40.5 60.3 33.4 51.0 37.5 55.9 28.1 29.1 34.9 22.5 22.3 28.7 40.7 47.7 142.2 129.0 13.9 20.5 43.9 43.1 18.6 27.2 58.2 19.1 18.6 44.9 25.5 40.9 38.4 20.9 23.2 49.2 58.7 33.9 18.3 45.0 17.8 25.6 21.7 43.3 16.8 31.7 38.5 21.9 23.7 26.6 72.6 23.5 16.1 37.0 23.8 29.9 27.6 16.9 23.1 11.4 20.8 22.1 46.8 20.2 33.3 36.1 18.1 17.0 44.4 33.2 30.7 29.5 47.0 25.1 44.5 37.7 41.4 10.7 31.8 16.7 19.8 17.8 24.3 4.8 32.3 31.6 30.4 55.2 30.3 20.8 18.2 34.3 33.6 11.1 30.2 30.2 42.4 24.8 83.8 43.8 68.4 27.9 24.0 18.0 27.2 66.8 47.2 32.0 21.3 26.5 22.8 20.8 16.1 15.8 18.7 45.2 30.9 20.7 27.4 18.6 27.8 11.9 26.4 19.5 14.2 21.3 43.5 21.8 21.0 20.9 34.7 22.9 29.6 6.0 32.0 11.3 26.7 37.0 12.7 40.6 49.2 40.5 60.3 40.7 47.7 43.9 43.1 44.9 45.0 43.3 72.6 23.3 22.4 25.8 129.3 29.8 56.0 131.4 74.9 34.1 35.3 39.1 24.1 28.6 42.9 51.3 36.8 102.2 53.6 18.8 53.5 115.4 27.4 230.2 48.0 21.4 33.3 37.8 13.0 46.4 29.4 22.3 27.7 29.6 39.3 10.2 41.1 89.3 117.4 35.3 25.2 51.5 31.4 71.2 15.7 11.7 62.9 34.8 15.9 46.2 52.5 14.1 35.5 39.1 104.0 141.1 15.6 26.6 45.5 23.3 27.9 32.4 376.2 47.6 50.5 39.5 29.9 26.2 18.0 29.4 45.5 40.6 20.0 30.7 61.7 62.7 67.8 HINT2 ENSG00000137133 "Histidine triad nucleotide binding protein 2" Q9BX68 9 35812960-35815354 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 633.9;Hepatocytes: 457.4;Proximal tubular cells: 578.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020961, HPA059109" Supported Enhanced Mitochondria "Intracellular and membrane" NA NA 110000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA020961: AB_1850715, HPA059109: AB_2683906" "unprognostic (9.64e-3)" "unprognostic (1.53e-2)" "unprognostic (3.02e-1)" "unprognostic (3.01e-2)" "unprognostic (5.51e-2)" "unprognostic (3.97e-2)" "unprognostic (1.07e-1)" "unprognostic (2.38e-2)" "unprognostic (2.61e-1)" "prognostic favorable (1.66e-4)" "unprognostic (3.71e-3)" "unprognostic (2.87e-2)" "prognostic favorable (2.97e-9)" "unprognostic (4.29e-2)" "unprognostic (1.41e-1)" "unprognostic (8.78e-2)" "unprognostic (1.72e-1)" 50.8 79.5 41.7 15.5 43.9 27.0 48.5 44.9 46.8 23.2 40.3 42.6 34.9 25.9 48.6 27.5 29.9 14.9 87.4 39.8 43.1 91.1 169.2 30.2 21.0 43.8 42.5 19.2 65.9 72.6 41.2 17.6 42.0 33.9 34.2 20.4 39.7 26.1 80.1 33.4 34.2 20.1 43.9 33.8 56.9 29.8 47.3 38.8 38.4 85.5 23.8 30.6 24.2 44.0 30.3 76.1 47.1 45.6 29.0 24.3 33.2 27.8 39.2 42.3 46.1 49.9 31.1 39.9 31.7 25.3 59.8 29.3 21.2 40.9 44.1 87.8 40.7 42.2 64.1 45.8 68.1 25.1 40.0 27.3 36.8 40.2 64.8 16.7 33.2 91.4 25.5 117.4 34.0 60.3 61.3 31.3 21.4 70.0 138.7 60.8 33.1 53.6 61.5 21.5 38.4 46.4 36.0 42.7 49.6 27.5 45.9 44.6 16.5 22.0 37.7 30.4 35.7 107.0 127.3 57.4 49.8 32.2 36.2 41.0 77.5 4.7 68.9 58.5 62.4 98.9 73.7 69.8 113.4 96.7 56.4 58.6 7.6 66.8 56.9 246.1 107.3 81.2 41.7 43.9 44.9 46.8 39.8 43.1 43.8 42.5 42.0 43.9 47.3 44.0 49.3 22.4 17.5 5.2 57.9 45.4 63.4 137.6 49.5 39.8 99.1 105.8 115.1 130.1 68.3 80.9 20.9 154.9 69.3 148.2 633.9 115.5 67.3 83.9 28.6 47.8 96.0 100.8 1.7 172.1 71.7 53.2 52.5 44.6 18.4 43.5 63.1 457.4 113.9 20.2 2.5 127.4 126.1 61.1 51.4 128.0 40.4 47.7 120.9 1.9 74.1 123.7 87.6 1.5 4.5 85.6 157.5 44.8 77.7 40.7 181.4 578.1 105.1 45.5 46.0 54.2 72.6 38.4 77.4 64.7 45.9 56.8 51.0 85.1 126.7 84.8 HK1 ENSG00000156515 "Hexokinase 1" P19367 10 69269984-69401884 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycolysis, Immunity, Inflammatory response, Innate immunity" "Allosteric enzyme, Kinase, Transferase" "Cancer-related genes, Charcot-Marie-Tooth disease, Disease variant, Mental retardation, Neurodegeneration, Neuropathy, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 374.0;Horizontal cells: 304.5;Late spermatids: 1034.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007043, HPA007044, CAB010052" Supported Supported Mitochondria NA NA 560000 "Cluster 51: Monocytes - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "CAB010052: AB_627721, HPA007043: AB_1850652, HPA007044: AB_1079049" "unprognostic (8.80e-2)" "unprognostic (1.78e-1)" "unprognostic (2.03e-1)" "unprognostic (2.00e-3)" "unprognostic (1.15e-2)" "prognostic unfavorable (3.39e-6)" "unprognostic (1.23e-1)" "unprognostic (1.97e-1)" "unprognostic (4.29e-2)" "unprognostic (1.16e-1)" "unprognostic (3.93e-3)" "unprognostic (1.12e-1)" "unprognostic (1.37e-3)" "unprognostic (7.25e-2)" "unprognostic (1.40e-2)" "unprognostic (2.00e-3)" "unprognostic (3.86e-2)" 47.0 24.4 61.0 45.0 65.7 60.3 40.6 58.0 76.6 54.7 64.2 60.1 13.1 41.3 11.2 129.9 37.0 25.7 150.8 69.1 62.7 49.2 8.5 48.1 34.1 56.7 59.8 19.9 12.3 25.0 44.9 49.3 71.1 52.9 31.9 147.6 67.1 53.1 193.5 102.6 29.2 49.8 40.0 40.3 61.6 77.2 53.5 44.9 71.0 146.7 47.6 74.3 80.9 54.1 101.6 56.6 74.2 71.1 81.0 60.4 47.1 98.3 256.5 128.5 138.0 16.3 11.0 7.3 75.8 165.9 92.9 86.2 69.9 220.0 122.0 67.5 54.5 250.0 58.3 1.1 91.7 5.1 181.2 91.5 125.8 184.5 407.6 160.8 135.4 36.8 424.5 51.3 178.7 167.7 29.7 13.1 113.8 51.7 247.0 44.8 45.0 0.6 88.7 117.4 75.7 88.7 112.6 215.4 65.2 104.3 117.7 16.5 140.4 190.5 86.4 106.5 139.6 61.1 42.8 17.4 247.3 130.4 56.1 68.7 88.8 44.6 41.5 125.2 69.0 33.5 47.9 47.6 81.0 19.9 41.7 33.9 20.9 31.2 135.4 9.1 58.1 110.4 61.0 65.7 58.0 76.6 69.1 62.7 56.7 59.8 71.1 40.0 53.5 54.1 26.1 25.6 32.4 38.2 26.5 48.3 50.5 37.8 43.9 83.9 33.1 21.7 130.6 4.3 34.2 27.6 54.2 70.6 14.6 30.3 13.7 28.6 374.0 32.6 28.0 37.9 18.7 104.8 53.8 30.6 93.3 30.3 41.3 34.5 23.4 72.6 26.7 1.1 49.4 304.5 49.8 28.7 44.7 41.7 21.9 1034.1 15.2 51.3 37.4 29.0 35.3 32.9 20.6 14.1 3.5 54.6 11.1 18.4 19.1 29.1 0.7 1.1 30.7 95.5 19.7 22.2 43.1 5.3 6.2 86.0 51.7 118.9 30.5 28.3 19.3 43.5 HKDC1 "FLJ22761, FLJ37767" ENSG00000156510 "Hexokinase domain containing 1" Q2TB90 10 69220332-69267552 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Glycolysis "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 53.5;retina: 46.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 31.5;Distal enterocytes: 29.0;Ductal cells: 32.6;Endometrial ciliated cells: 50.0;Glandular and luminal cells: 55.2;Muller glia cells: 126.9;Proximal enterocytes: 56.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 20.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory CD4 T-cell: 3.1;naive CD4 T-cell: 5.8;naive CD8 T-cell: 2.3;T-reg: 5.4" "Lineage enriched" "Detected in single" 23 "T-cells: 5.8" "Cell line enhanced" "Detected in some" "A549: 40.1;CACO-2: 57.5;CAPAN-2: 111.4;EFO-21: 33.9;GAMG: 45.4;Hep G2: 33.6;RPTEC TERT1: 81.9" "Region enhanced" "Detected in many" "cerebral cortex: 11.9" "Low region specificity" "Detected in all" "HPA064198, HPA064230" Enhanced Enhanced Mitochondria No No "Cluster 20: T-cells - T-cell receptor" "Cluster 56: Intestine - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 5: Muller glia cells - Visual perception" Mitochondria "HPA064198: AB_2685210, HPA064230: AB_2685219" "unprognostic (1.29e-2)" "unprognostic (2.26e-2)" "unprognostic (1.86e-1)" "unprognostic (8.47e-2)" "unprognostic (1.55e-1)" "unprognostic (3.05e-1)" "unprognostic (6.31e-3)" "unprognostic (5.03e-2)" "unprognostic (1.08e-1)" "unprognostic (1.19e-1)" "unprognostic (1.23e-3)" "unprognostic (3.11e-1)" "unprognostic (1.04e-3)" "unprognostic (1.35e-1)" "unprognostic (2.24e-1)" "unprognostic (2.10e-3)" "unprognostic (2.19e-1)" 0.1 0.0 1.1 2.7 1.3 0.0 0.0 1.4 1.0 1.1 1.4 6.8 53.5 0.9 0.0 0.1 4.6 6.8 0.0 1.0 1.1 13.3 4.6 1.5 1.0 1.3 2.1 0.0 6.2 0.0 0.3 0.0 1.7 0.0 4.2 46.8 0.1 0.0 0.0 0.1 48.0 0.5 1.4 0.3 1.1 1.0 1.0 5.2 9.3 0.0 0.2 0.0 0.1 1.2 1.2 40.1 0.2 0.1 0.0 0.0 0.2 0.0 0.3 0.1 0.1 57.5 111.4 0.0 33.9 0.3 45.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 33.6 2.7 0.0 0.0 0.0 0.3 0.4 3.2 0.6 0.0 11.3 0.0 0.0 0.7 0.1 0.2 0.1 0.0 11.9 1.3 0.0 1.2 0.1 81.9 0.1 0.0 0.0 0.0 0.0 1.3 0.3 0.0 0.0 0.0 0.4 1.6 0.2 0.8 0.0 0.1 0.0 8.1 0.0 0.5 0.0 0.0 0.0 0.6 0.0 0.5 0.0 3.1 1.0 0.0 0.0 5.8 2.3 0.0 0.2 0.0 0.0 5.4 1.0 1.1 1.3 1.4 1.0 1.0 1.1 1.3 2.1 1.7 1.4 1.0 1.2 0.0 3.2 4.8 11.8 0.7 0.0 0.0 0.3 0.0 1.9 0.0 0.0 1.0 31.5 1.0 16.5 0.0 0.0 0.2 29.0 1.9 32.6 0.6 50.0 4.5 0.5 0.0 0.0 0.4 7.3 0.0 0.2 1.5 55.2 0.0 0.0 0.0 0.4 0.1 3.3 0.5 5.6 0.0 0.3 0.0 0.2 0.3 0.4 0.0 0.0 0.0 126.9 0.0 0.0 0.5 25.5 12.7 0.0 0.3 0.0 56.3 15.7 0.3 5.1 0.0 0.1 0.4 0.0 0.2 0.0 0.0 0.0 1.3 0.1 5.6 0.3 HMGCS2 ENSG00000134240 "3-hydroxy-3-methylglutaryl-CoA synthase 2" P54868 1 119748002-119768905 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 2434.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 327.2;Hepatocytes: 1118.3;Intestinal goblet cells: 226.8;Paneth cells: 177.7;Undifferentiated cells: 282.3" "Cancer enriched" "Detected in many" 5 "liver cancer: 441.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "OE19: 113.6;RT4: 201.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027423, HPA027442, CAB032906" Enhanced Approved Mitochondria NA NA 830000 "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 2: Hepatocytes - Metabolism" Mitochondria "CAB032906: AB_2118322, HPA027423: AB_2672266, HPA027442: AB_2672277" "unprognostic (2.57e-1)" "unprognostic (1.12e-1)" "unprognostic (3.93e-2)" "unprognostic (7.62e-2)" "unprognostic (1.49e-2)" "prognostic favorable (2.43e-7)" "unprognostic (9.68e-2)" "unprognostic (3.21e-2)" "prognostic favorable (2.17e-4)" "unprognostic (1.20e-1)" "unprognostic (6.42e-2)" "prognostic favorable (3.43e-5)" "unprognostic (9.57e-2)" "unprognostic (2.31e-1)" "unprognostic (5.00e-2)" "unprognostic (1.54e-3)" 1.0 0.3 0.0 7.3 0.0 0.0 222.4 0.0 0.0 0.1 5.2 366.7 165.6 1.4 0.4 4.3 0.4 4.3 36.6 0.0 0.1 64.9 2434.1 2.2 0.1 0.0 0.1 0.1 20.1 0.1 0.1 0.4 0.0 34.0 228.0 0.1 50.8 0.6 6.9 14.2 151.8 23.7 0.0 0.6 101.2 35.6 0.0 0.4 0.6 3.1 0.0 36.5 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 12.9 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.2 113.6 0.1 0.2 0.7 0.7 0.0 201.6 0.1 0.8 0.6 0.0 0.0 0.1 7.6 0.0 0.0 0.0 0.5 0.1 0.0 0.2 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.2 10.8 0.0 2.4 0.1 3.7 0.0 1.2 0.0 18.8 5.6 8.7 42.9 0.1 31.3 0.0 0.8 0.0 327.2 0.0 0.0 1.9 0.6 0.1 1.1 73.1 24.0 0.0 0.0 0.2 0.2 66.8 1.4 4.5 19.5 16.4 1118.3 0.2 0.0 0.0 226.8 0.0 26.1 0.7 3.9 1.5 0.2 5.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 177.7 0.0 0.0 6.3 12.4 0.9 0.0 0.0 6.6 0.0 0.1 0.4 0.5 1.9 0.3 9.4 2.2 0.1 282.3 26.5 HRNR "FLG3, S100A16, S100a18" ENSG00000197915 Hornerin Q86YZ3 1 152212076-152224193 "Plasma proteins, Predicted intracellular proteins" Keratinization "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.9" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 1.0;Horizontal cells: 1.7;Rod photoreceptor cells: 3.5" "Cancer enriched" "Detected in single" 4 "melanoma: 1.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NTERA-2: 1.9" "Not detected" "Not detected" HPA031469 Uncertain Approved Mitochondria No No 180000000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 46: Photoreceptor cells - Phototransduction" Mitochondria "HPA031469: AB_10603771" "unprognostic (1.34e-1)" "unprognostic (4.51e-2)" "unprognostic (3.01e-2)" "unprognostic (8.72e-4)" "unprognostic (1.61e-2)" "unprognostic (1.45e-1)" "unprognostic (2.11e-1)" "unprognostic (1.79e-1)" "unprognostic (6.09e-2)" "unprognostic (3.38e-2)" "unprognostic (1.87e-2)" "unprognostic (1.59e-2)" "unprognostic (1.65e-2)" "unprognostic (2.49e-2)" "unprognostic (1.71e-1)" "unprognostic (2.07e-1)" "unprognostic (3.64e-2)" 0.1 0.2 0.9 0.0 0.4 0.0 0.1 0.0 0.6 0.2 0.3 0.1 0.0 0.2 0.0 0.5 0.2 0.0 0.2 0.4 1.9 0.3 0.1 0.1 0.0 1.8 0.7 0.4 0.4 0.0 0.2 0.0 1.1 0.2 0.0 0.3 0.1 0.0 0.0 0.6 0.1 0.0 0.3 0.1 0.1 0.4 0.7 0.0 0.3 0.0 0.0 0.1 0.2 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.4 0.0 0.4 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.4 0.0 0.6 0.4 1.9 1.8 0.7 1.1 0.3 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 HS2ST1 KIAA0448 ENSG00000153936 "Heparan sulfate 2-O-sulfotransferase 1" Q7LGA3 1 86914635-87109982 "Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 160.9;Excitatory neurons: 126.1;Inhibitory neurons: 130.1;Oligodendrocyte precursor cells: 95.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "HPA043069, HPA043603, HPA075001" Supported Approved Mitochondria "Intracellular and membrane" No No "Cluster 38: Basophils - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "HPA043069: AB_10964127, HPA043603: AB_10963432, HPA075001: AB_2686726" "unprognostic (1.04e-1)" "unprognostic (1.50e-1)" "unprognostic (1.28e-3)" "unprognostic (8.06e-2)" "unprognostic (1.87e-1)" "unprognostic (7.13e-2)" "prognostic unfavorable (6.88e-4)" "unprognostic (7.20e-2)" "unprognostic (5.34e-2)" "unprognostic (7.70e-2)" "unprognostic (1.70e-3)" "unprognostic (1.45e-1)" "unprognostic (5.80e-2)" "unprognostic (1.63e-2)" "unprognostic (5.07e-2)" "unprognostic (3.24e-1)" "unprognostic (7.58e-2)" 8.0 25.7 11.5 9.4 13.8 3.8 8.1 8.0 12.2 10.5 13.2 9.3 9.7 9.1 9.9 7.0 6.7 10.6 7.0 11.9 11.4 13.8 17.2 8.2 11.8 10.1 11.0 12.7 10.1 13.4 6.6 8.3 8.1 9.5 9.0 19.3 6.7 9.9 4.4 8.2 9.3 7.8 8.8 12.7 8.3 9.3 12.2 10.6 12.9 4.7 11.6 9.4 5.9 8.4 24.4 20.4 59.0 38.5 31.9 92.3 20.4 23.3 30.5 19.2 21.2 78.1 30.6 53.3 22.1 16.4 33.2 14.5 27.2 19.5 30.8 42.1 22.2 64.0 21.0 63.0 13.4 33.6 31.0 38.2 17.0 31.0 25.6 30.4 28.8 29.7 44.6 27.4 28.1 8.6 33.8 20.2 19.8 26.5 12.9 41.2 55.7 11.6 23.5 50.3 12.6 19.0 30.6 26.2 27.2 15.2 17.2 15.2 25.7 24.0 29.8 42.2 29.7 25.1 19.9 49.7 14.8 23.6 25.0 6.2 1.1 1.0 1.3 0.6 1.6 1.1 1.5 1.5 0.7 2.8 1.4 0.9 1.2 1.1 2.8 0.7 0.9 1.0 11.5 13.8 8.0 12.2 11.9 11.4 10.1 11.0 8.1 8.8 12.2 8.4 13.0 16.0 12.4 160.9 14.2 16.6 8.6 9.3 19.9 10.9 11.9 7.6 12.8 14.3 15.2 20.2 4.2 8.2 5.7 13.5 13.7 18.2 5.5 7.1 23.6 13.8 23.4 12.2 126.1 11.5 9.3 16.9 11.2 8.0 19.0 74.2 18.2 28.9 37.7 8.4 130.1 12.5 18.3 12.8 13.5 3.8 6.8 15.3 12.4 53.4 8.2 28.8 5.2 95.0 54.5 11.3 7.7 20.3 24.0 7.3 17.6 18.3 11.2 17.7 0.0 21.1 16.8 10.1 15.0 12.8 15.8 4.4 12.9 77.4 13.5 7.1 HSDL2 "C9orf99, SDR13C1" ENSG00000119471 "Hydroxysteroid dehydrogenase like 2" Q6YN16 9 112380080-112472405 "Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 181.3" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 214.8;Early spermatids: 153.9;Granulosa cells: 187.2;Late spermatids: 163.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Lineage enriched" "Detected in all" 5 "granulocytes: 54.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042890, HPA050453" Enhanced Enhanced Mitochondria NA NA "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "HPA042890: AB_2678216, HPA050453: AB_2681131" "unprognostic (3.17e-3)" "unprognostic (1.62e-2)" "unprognostic (1.90e-3)" "prognostic favorable (9.23e-6)" "unprognostic (3.94e-2)" "unprognostic (1.43e-2)" "unprognostic (1.17e-1)" "unprognostic (5.15e-2)" "unprognostic (7.58e-2)" "unprognostic (6.48e-2)" "unprognostic (1.57e-1)" "unprognostic (1.82e-1)" "prognostic favorable (9.29e-7)" "unprognostic (1.44e-1)" "unprognostic (2.33e-1)" "unprognostic (1.35e-2)" "unprognostic (7.35e-2)" 76.3 63.6 28.1 13.3 30.1 11.6 22.8 25.1 29.5 23.3 27.6 31.7 38.9 22.8 11.5 29.8 21.2 19.0 89.9 24.8 33.1 69.0 149.0 28.7 13.9 25.4 33.2 50.8 20.0 21.8 8.8 16.8 27.1 20.3 26.9 12.6 18.8 15.9 151.7 31.1 32.2 20.5 26.6 18.6 24.6 14.0 32.0 19.6 30.4 181.3 15.8 29.2 15.0 28.5 45.0 39.4 29.0 14.8 49.0 48.4 33.4 30.1 18.6 21.1 17.7 77.0 49.4 28.5 16.2 44.4 26.9 50.6 31.9 42.2 25.8 120.9 21.0 30.0 58.5 76.1 30.7 17.1 18.5 52.0 29.9 31.3 22.8 30.5 24.8 34.7 42.3 18.9 58.2 29.6 42.5 15.3 17.2 106.9 50.3 27.1 87.4 42.7 44.5 40.4 20.7 14.5 75.8 49.5 26.0 23.7 70.0 20.0 28.3 30.2 27.9 85.2 29.6 21.5 57.3 13.5 37.0 24.8 18.2 54.3 8.4 32.8 4.6 8.1 6.8 6.9 4.8 5.0 9.5 8.4 5.6 5.9 48.0 5.9 11.5 9.4 8.7 4.9 28.1 30.1 25.1 29.5 24.8 33.1 25.4 33.2 27.1 26.6 32.0 28.5 32.0 99.3 84.3 48.6 14.1 13.3 17.5 21.6 29.6 9.3 12.0 13.3 214.8 14.3 32.2 14.7 6.2 26.5 18.3 23.7 64.6 15.5 153.9 38.6 38.3 19.1 14.9 32.8 10.8 18.7 30.9 31.1 29.0 27.8 30.4 187.2 17.2 124.2 35.7 6.7 12.2 32.2 8.2 23.6 12.5 163.0 27.4 27.5 8.8 15.9 47.3 24.1 6.2 16.1 19.3 13.2 23.5 47.0 20.9 16.0 52.4 111.1 37.7 14.5 46.0 18.1 46.9 12.9 16.4 34.2 16.2 31.7 16.2 108.9 36.2 29.5 HSPA9 "GRP75, HSPA9B, mot-2, mthsp75, PBP74" ENSG00000113013 "Heat shock protein family A (Hsp70) member 9" P38646 5 138553756-138575675 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Chaperone "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000898, CAB005219" Supported Supported Mitochondria NA NA 3600000 "Cluster 27: Non-specific - Gene expression" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB005219: AB_647720, HPA000898: AB_1079032" "prognostic unfavorable (2.93e-4)" "unprognostic (1.86e-1)" "prognostic favorable (4.53e-4)" "unprognostic (3.73e-2)" "unprognostic (2.33e-1)" "unprognostic (9.06e-2)" "unprognostic (2.05e-2)" "unprognostic (1.10e-1)" "unprognostic (9.85e-2)" "unprognostic (2.53e-1)" "unprognostic (2.74e-1)" "unprognostic (1.31e-1)" "unprognostic (8.78e-3)" "unprognostic (1.02e-1)" "unprognostic (2.15e-1)" "unprognostic (3.27e-2)" "unprognostic (2.29e-1)" 88.6 226.3 10.3 51.5 15.1 98.8 72.4 25.4 26.0 60.3 28.8 80.3 61.2 67.0 33.9 87.8 56.5 38.3 179.5 10.9 19.6 112.1 194.2 62.5 43.6 19.6 20.7 80.0 79.8 169.4 71.4 46.5 23.8 56.4 56.5 48.8 78.9 46.7 288.9 77.5 64.3 44.2 21.6 54.7 91.8 50.1 17.8 44.6 91.3 193.6 55.7 73.8 65.6 29.1 196.0 276.6 111.4 231.0 138.1 94.3 274.7 198.3 196.7 255.4 268.6 579.4 194.4 419.3 263.7 150.8 382.0 158.6 334.0 314.1 298.2 219.7 177.9 230.5 209.0 270.4 360.4 229.0 201.3 142.6 317.7 299.5 494.8 78.7 128.0 167.8 280.4 297.5 134.7 220.6 206.7 82.9 182.5 191.6 173.3 252.1 188.8 302.4 192.8 267.4 150.1 112.4 242.5 338.5 630.7 269.0 230.5 200.5 117.7 204.1 126.5 174.9 313.5 324.6 300.5 378.6 249.6 301.4 202.6 11.8 31.3 10.7 39.8 34.9 46.2 31.7 30.6 36.8 42.0 22.4 34.1 33.9 4.3 28.3 38.8 17.9 31.3 53.6 10.3 15.1 25.4 26.0 10.9 19.6 19.6 20.7 23.8 21.6 17.8 29.1 63.0 99.3 123.8 43.1 101.7 87.8 228.6 157.2 84.8 88.2 83.4 63.8 337.3 70.1 153.8 99.3 83.4 194.7 114.7 80.8 223.0 151.4 12.1 90.1 98.4 83.1 73.0 75.1 41.1 106.1 132.9 109.6 73.9 126.6 167.8 86.1 43.5 175.9 133.9 99.3 48.4 95.4 148.5 54.1 76.4 12.6 67.4 100.1 83.6 25.3 92.3 92.5 43.3 27.6 43.3 93.8 66.0 72.6 102.3 131.1 85.8 231.3 119.7 89.3 46.0 134.3 136.2 52.5 91.4 93.2 73.9 175.5 130.7 157.9 150.7 141.2 HSPBAP1 "FLJ22623, PASS1" ENSG00000169087 "HSPB1 associated protein 1" Q96EW2 3 122739999-122793831 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 60.5;Microglial cells: 52.5;Syncytiotrophoblasts: 48.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044930 Approved Approved Mitochondria NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 23: Testis - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "HPA044930: AB_10961122" "unprognostic (3.40e-3)" "unprognostic (1.22e-2)" "unprognostic (2.98e-2)" "unprognostic (6.70e-3)" "unprognostic (3.40e-3)" "unprognostic (3.40e-2)" "unprognostic (8.61e-4)" "unprognostic (2.68e-2)" "unprognostic (6.95e-2)" "unprognostic (3.35e-2)" "unprognostic (2.36e-1)" "unprognostic (8.91e-2)" "unprognostic (1.24e-3)" "unprognostic (4.29e-1)" "unprognostic (1.33e-1)" "unprognostic (3.34e-1)" "unprognostic (4.12e-3)" 4.2 5.4 2.9 4.3 3.3 3.1 3.8 3.4 4.2 3.8 4.1 3.7 2.5 3.8 1.9 2.8 3.1 3.5 3.2 3.3 3.5 4.3 3.5 4.6 6.2 4.0 3.4 3.0 3.8 3.7 2.7 6.0 4.0 3.3 3.4 4.6 3.2 3.2 15.9 4.3 3.8 3.8 3.4 7.3 3.0 10.7 3.4 6.4 6.2 8.7 5.5 4.3 3.2 3.9 5.4 4.1 5.8 5.2 6.8 5.1 11.3 2.6 6.7 6.1 8.6 5.6 4.1 6.9 4.2 1.8 15.4 6.4 9.0 5.0 7.1 4.3 2.5 4.6 4.8 3.3 15.4 4.2 6.1 7.7 18.0 5.1 16.3 5.8 5.8 6.9 3.1 5.8 5.6 3.5 6.1 5.3 6.6 4.2 8.2 6.2 7.8 6.8 6.4 2.1 6.4 6.5 6.2 2.4 23.3 5.5 2.9 8.8 5.8 7.1 4.2 2.3 3.7 5.7 6.1 8.1 4.4 6.2 7.1 23.0 16.5 12.0 6.1 12.2 7.6 11.0 8.0 6.1 13.0 8.3 8.6 8.4 30.6 6.3 24.1 4.5 10.3 8.2 2.9 3.3 3.4 4.2 3.3 3.5 4.0 3.4 4.0 3.4 3.4 3.9 10.2 6.4 5.3 10.7 20.8 10.7 3.9 5.0 6.8 6.6 3.9 5.7 5.7 4.3 3.9 5.5 60.5 16.8 11.4 4.9 3.9 5.5 35.7 7.3 5.1 6.4 0.0 7.2 15.2 6.0 11.0 6.5 5.6 4.4 6.3 6.4 11.0 3.6 12.9 8.4 24.7 3.1 4.1 24.1 14.1 8.0 9.6 20.1 5.4 52.5 29.4 3.7 14.4 8.0 22.9 4.3 3.5 4.9 6.4 3.2 6.3 4.5 5.9 12.8 6.6 7.1 4.9 36.8 8.4 5.0 7.5 48.6 10.3 7.4 3.5 1.7 HSPD1 "GroEL, HSP60, SPG13" ENSG00000144381 "Heat shock protein family D (Hsp60) member 1" P10809 2 197486584-197516737 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction" "Chaperone, Isomerase" "Cancer-related genes, Disease variant, Hereditary spastic paraplegia, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 790.6" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 1737.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001523, CAB002775, HPA050025, CAB072816" Supported Enhanced Mitochondria NA NA 18000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 35: Non-specific - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" Mitochondria "CAB002775: , CAB072816: , HPA001523: AB_1079028, HPA050025: AB_2680995" "unprognostic (2.79e-2)" "unprognostic (1.72e-2)" "unprognostic (5.21e-2)" "prognostic unfavorable (1.61e-4)" "unprognostic (2.59e-1)" "unprognostic (3.57e-3)" "prognostic unfavorable (2.25e-4)" "unprognostic (3.51e-2)" "unprognostic (9.91e-2)" "unprognostic (8.63e-3)" "unprognostic (3.47e-2)" "unprognostic (7.83e-3)" "unprognostic (5.64e-3)" "unprognostic (1.73e-2)" "unprognostic (1.52e-1)" "unprognostic (2.61e-2)" "unprognostic (4.10e-2)" 179.4 790.6 188.6 128.3 191.6 110.6 168.8 204.9 401.9 96.9 217.8 170.0 158.1 90.8 89.3 124.5 132.6 69.1 145.0 184.3 198.6 374.9 462.6 136.6 149.2 199.6 198.5 167.6 219.0 159.2 116.0 148.6 205.3 104.5 195.1 71.8 93.9 93.6 162.7 83.3 148.7 104.5 195.1 94.6 155.4 57.6 198.6 99.3 138.7 176.7 172.7 144.6 92.3 201.4 559.7 650.1 541.3 496.9 373.6 389.2 786.5 573.2 304.7 686.1 495.6 2219.1 326.2 1724.4 730.0 304.1 834.2 538.4 2232.9 633.2 943.0 417.0 888.2 1209.8 984.8 2562.8 353.2 1331.4 349.1 445.5 717.1 599.5 1053.2 471.4 542.6 919.1 1535.3 606.8 501.7 690.4 853.6 1304.2 1086.4 735.2 1424.9 1000.1 679.7 1235.5 709.5 539.7 716.5 400.8 582.0 608.5 771.0 1116.3 425.0 789.4 242.2 405.8 570.4 532.8 910.0 331.1 861.4 1399.5 485.7 795.3 456.7 12.1 52.3 11.4 36.4 81.8 71.7 63.8 59.6 54.3 84.6 54.0 81.0 70.3 11.0 62.6 72.1 49.4 51.8 70.6 188.6 191.6 204.9 401.9 184.3 198.6 199.6 198.5 205.3 195.1 198.6 201.4 216.4 166.7 172.5 38.8 220.4 246.6 1737.2 247.5 264.0 75.8 216.0 263.1 239.2 195.9 287.9 79.1 256.5 825.7 197.7 213.7 375.6 235.0 6.2 322.2 304.5 233.9 274.6 241.6 31.9 145.9 419.8 356.0 215.6 445.2 299.5 407.1 63.1 312.5 328.0 95.9 47.2 302.2 166.8 88.6 479.3 12.8 130.5 381.9 163.7 30.0 138.5 125.7 68.0 20.6 35.6 171.4 163.2 113.6 322.9 705.9 160.1 797.1 328.6 117.1 85.5 199.0 471.7 88.5 106.0 262.4 207.1 1001.2 467.2 1017.4 512.1 861.5 HTRA2 "OMI, PARK13, PRSS25" ENSG00000115317 "HtrA serine peptidase 2" O43464 2 74529725-74533332 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins" Apoptosis "Hydrolase, Protease, Serine protease" "Disease variant, Epilepsy, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 118.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004004, HPA006602, HPA027366" Uncertain Supported Mitochondria NA NA 260000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria "CAB004004: AB_326421, HPA006602: AB_2667622, HPA027366: AB_1851301" "unprognostic (3.09e-1)" "unprognostic (4.06e-2)" "unprognostic (2.82e-1)" "unprognostic (2.58e-2)" "unprognostic (1.56e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (7.77e-8)" "unprognostic (2.12e-3)" "unprognostic (4.18e-1)" "unprognostic (1.15e-1)" "unprognostic (4.57e-2)" "unprognostic (8.15e-2)" "unprognostic (7.23e-3)" "unprognostic (4.03e-1)" "unprognostic (1.73e-1)" "unprognostic (1.72e-1)" "unprognostic (2.06e-2)" 11.4 8.6 8.1 8.1 8.7 11.1 6.8 9.1 9.7 7.1 7.7 6.4 6.9 6.9 1.0 6.0 7.1 4.7 9.4 8.1 8.3 8.1 6.5 6.6 7.8 8.6 8.5 10.9 7.4 9.4 4.7 6.3 8.3 4.8 3.3 2.5 8.5 5.3 14.5 5.4 7.9 5.3 8.2 9.9 6.4 6.2 9.6 9.1 6.8 9.0 4.8 6.5 5.8 9.2 19.1 14.7 14.7 12.6 21.3 9.0 30.1 17.0 10.3 10.3 7.0 21.1 8.5 16.6 12.9 10.7 26.0 19.7 12.0 19.6 2.4 34.0 31.4 33.3 10.8 19.0 19.8 15.3 22.4 9.9 13.7 18.4 19.5 18.4 14.2 23.5 43.9 24.9 9.7 14.1 22.0 31.1 10.0 22.8 37.7 15.8 37.0 17.1 9.6 8.2 15.1 17.7 8.9 18.6 32.5 7.3 9.3 13.2 10.6 19.2 19.7 33.4 35.3 29.5 10.2 9.8 13.6 23.4 13.0 5.8 7.0 4.0 4.8 5.7 5.8 11.0 4.8 4.1 8.6 9.9 4.3 4.1 2.6 5.0 4.5 4.5 5.7 5.5 8.1 8.7 9.1 9.7 8.1 8.3 8.6 8.5 8.3 8.2 9.6 9.2 30.7 0.0 4.8 6.2 27.3 20.6 19.7 33.8 13.6 12.0 17.4 21.7 0.9 21.5 15.7 11.0 0.0 24.7 25.8 12.5 35.2 32.4 30.8 11.9 18.1 29.6 9.0 118.5 6.3 17.7 37.8 23.3 11.2 12.9 27.3 20.9 22.9 12.7 31.5 10.1 6.3 12.3 20.3 10.7 19.4 48.9 24.8 14.6 30.2 2.8 26.3 20.2 30.9 5.5 7.5 26.1 16.8 20.7 36.0 21.3 24.8 36.8 13.5 16.3 26.3 18.7 56.5 64.3 43.3 16.7 22.0 20.2 20.6 27.1 20.0 15.7 IARS2 FLJ10326 ENSG00000067704 "Isoleucyl-tRNA synthetase 2, mitochondrial" Q9NSE4 1 220094132-220148041 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Cataract, Deafness, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024212, HPA024594, HPA024596" Enhanced Enhanced Mitochondria NA NA 35000 "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA024212: AB_1851363, HPA024594: AB_1851368, HPA024596: AB_1851370" "unprognostic (2.15e-2)" "prognostic unfavorable (1.04e-4)" "unprognostic (2.42e-3)" "unprognostic (3.22e-2)" "unprognostic (2.04e-1)" "unprognostic (1.55e-1)" "unprognostic (1.91e-1)" "unprognostic (7.81e-2)" "unprognostic (1.78e-1)" "unprognostic (1.91e-1)" "prognostic unfavorable (9.24e-5)" "unprognostic (9.48e-2)" "unprognostic (2.10e-2)" "unprognostic (3.01e-1)" "unprognostic (2.16e-1)" "unprognostic (8.87e-2)" "unprognostic (6.27e-3)" 55.8 49.8 19.9 33.3 21.1 18.3 41.8 23.5 25.4 35.3 37.8 54.2 43.4 31.8 31.4 47.9 41.4 30.5 60.0 20.0 21.8 65.5 83.8 31.0 38.8 22.7 22.2 39.0 33.6 80.5 16.0 40.7 25.0 36.1 54.8 34.8 40.0 37.5 92.9 40.5 40.4 39.4 21.6 28.4 39.1 30.1 22.3 31.8 39.7 85.7 43.1 35.6 30.0 22.9 137.2 125.6 70.7 69.9 104.2 104.4 169.6 81.4 86.9 87.9 70.7 121.7 138.8 125.6 107.1 101.4 68.0 129.3 99.0 101.5 100.9 87.5 119.3 62.6 94.6 137.8 64.6 100.4 64.9 76.0 101.3 95.4 97.6 84.7 86.9 79.9 156.9 70.7 116.7 75.9 79.8 72.0 92.1 106.2 82.1 69.5 140.7 202.2 126.2 90.4 38.0 106.6 123.2 188.2 130.3 80.6 218.5 111.9 89.8 86.1 71.6 117.0 138.4 60.0 98.9 90.8 91.3 77.3 97.6 33.8 24.6 22.8 23.0 27.7 30.8 23.6 24.9 30.3 29.2 18.3 27.8 25.6 4.7 28.3 22.3 10.6 29.9 26.7 19.9 21.1 23.5 25.4 20.0 21.8 22.7 22.2 25.0 21.6 22.3 22.9 66.4 35.3 38.0 15.7 30.7 20.1 28.6 44.1 34.7 28.6 40.1 39.4 144.3 22.8 42.9 29.5 25.0 79.0 31.5 54.2 11.7 47.7 20.0 63.8 48.3 43.7 36.2 29.6 17.3 65.4 55.5 37.0 32.1 44.3 19.6 41.3 37.5 99.6 45.9 20.2 22.7 55.4 28.5 51.0 11.2 6.8 37.3 35.9 19.6 15.0 46.1 34.6 27.8 16.6 31.5 67.4 44.9 42.5 33.1 34.1 38.4 36.1 62.0 35.5 46.0 46.3 39.0 44.6 44.1 63.5 26.6 71.7 31.0 54.4 69.9 27.6 IBA57 "C1orf69, FLJ12734" ENSG00000181873 "Iron-sulfur cluster assembly factor IBA57" Q5T440 1 228165804-228182257 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Heme biosynthesis" Transferase "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythroid cells: 49.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030555, HPA030556, HPA030557" Approved Supported Mitochondria NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 6: Erythroid cells - Oxygen transport" Mitochondria "HPA030555: AB_2673522, HPA030556: AB_2673523, HPA030557: AB_10670433" "unprognostic (3.00e-2)" "unprognostic (1.71e-1)" "unprognostic (1.36e-1)" "unprognostic (1.29e-2)" "unprognostic (1.34e-1)" "unprognostic (8.16e-3)" "unprognostic (1.03e-1)" "unprognostic (6.11e-2)" "unprognostic (7.01e-2)" "unprognostic (8.00e-3)" "unprognostic (2.87e-2)" "unprognostic (1.61e-1)" "prognostic favorable (1.71e-9)" "unprognostic (4.94e-2)" "unprognostic (5.02e-1)" "unprognostic (5.04e-3)" "unprognostic (7.14e-2)" 2.0 2.7 2.6 1.4 2.3 4.1 1.4 2.9 2.5 1.3 2.2 1.8 1.6 1.8 0.5 1.6 1.3 1.0 3.3 2.1 2.0 2.0 2.8 1.9 1.6 2.7 2.2 1.9 2.9 2.1 0.9 1.4 2.3 1.2 1.4 0.5 1.7 1.0 6.1 3.0 1.7 1.7 2.1 1.7 2.0 1.1 2.8 1.3 1.3 4.0 1.7 1.3 1.2 3.5 2.5 2.5 2.7 1.2 1.3 1.4 3.3 1.5 0.7 1.1 0.6 5.3 2.1 5.3 3.1 1.6 0.6 4.4 2.0 3.2 1.0 1.1 4.5 3.1 3.5 2.6 1.1 3.7 3.5 2.2 1.8 1.3 1.5 1.0 1.6 3.2 5.4 2.4 1.1 2.0 3.6 2.2 2.0 3.4 2.8 4.4 3.1 2.4 1.6 5.1 4.1 2.8 2.4 7.5 1.9 0.5 6.0 4.9 3.8 3.0 2.8 2.1 3.7 1.8 0.9 2.6 1.4 1.6 2.3 1.6 0.4 0.2 0.6 0.4 1.0 0.4 0.5 0.5 0.3 0.7 0.7 0.7 0.5 0.8 0.4 1.0 0.5 0.2 2.6 2.3 2.9 2.5 2.1 2.0 2.7 2.2 2.3 2.1 2.8 3.5 5.7 9.6 11.0 4.2 10.2 8.2 8.8 3.9 2.8 5.8 5.6 5.6 15.3 8.6 9.2 0.0 12.5 10.7 5.0 14.5 7.9 5.4 22.2 5.2 6.0 8.8 7.2 49.3 3.8 6.9 8.6 5.2 5.1 10.3 15.2 6.7 5.3 7.9 5.5 3.3 4.1 8.0 4.1 4.4 6.4 30.7 3.7 6.0 7.2 6.5 4.2 4.4 4.1 3.0 5.8 8.8 6.3 7.2 5.8 6.3 9.4 6.7 3.2 19.5 6.6 9.7 4.7 14.9 11.2 4.4 6.0 16.3 7.2 8.3 11.9 8.3 ICA1L "ALS2CR14, ALS2CR15" ENSG00000163596 "Islet cell autoantigen 1 like" Q8NDH6 2 202773150-202871766 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 171.7;Inhibitory neurons: 114.3;Oligodendrocyte precursor cells: 93.5;Rod photoreceptor cells: 84.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 21.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042507 Approved Approved Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 58: Brain - Synaptic function" "Cluster 28: BEWO - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Mitochondria "HPA042507: AB_10797016" "unprognostic (4.14e-3)" "unprognostic (3.60e-3)" "unprognostic (5.15e-2)" "unprognostic (5.63e-3)" "unprognostic (1.96e-1)" "unprognostic (2.36e-1)" "unprognostic (1.38e-1)" "unprognostic (8.05e-4)" "unprognostic (1.66e-1)" "unprognostic (9.60e-2)" "unprognostic (4.50e-4)" "unprognostic (4.15e-1)" "unprognostic (8.15e-3)" "unprognostic (2.97e-2)" "unprognostic (1.74e-1)" "unprognostic (9.79e-2)" "unprognostic (1.58e-3)" 3.8 4.8 9.8 1.3 12.0 3.9 3.5 23.2 20.6 7.1 7.4 6.8 1.5 7.5 5.7 2.6 9.5 3.6 4.9 13.4 13.7 3.2 0.5 2.2 1.5 3.7 5.5 8.1 2.7 7.1 15.7 5.2 1.6 5.5 1.6 17.5 1.9 6.1 5.1 1.9 2.0 4.6 3.3 1.4 3.7 8.3 9.9 2.7 5.1 6.7 1.2 5.4 3.4 8.7 1.5 1.2 2.9 8.4 2.7 5.0 21.8 2.9 3.8 1.6 2.3 1.4 0.6 1.7 0.8 3.5 4.6 0.8 4.0 1.4 2.1 1.5 3.1 3.6 1.8 1.8 1.5 4.4 2.1 1.9 2.4 1.7 1.4 4.9 2.4 5.6 2.8 1.6 2.5 0.7 3.6 6.0 8.4 0.5 3.1 4.3 4.4 0.7 1.6 3.9 7.8 7.5 4.5 0.2 1.9 2.4 1.0 3.4 1.6 7.0 1.8 1.5 4.4 5.5 8.9 4.5 4.0 1.4 1.3 1.2 1.1 0.6 0.9 1.2 0.7 1.3 0.8 0.7 1.6 2.3 1.1 1.6 1.5 2.3 2.1 1.1 0.7 0.7 9.8 12.0 23.2 20.6 13.4 13.7 3.7 5.5 1.6 3.3 9.9 8.7 13.0 9.6 10.0 62.0 10.5 2.0 4.4 2.9 1.2 58.7 4.1 2.8 15.2 1.5 8.7 18.4 60.5 16.3 5.7 1.0 0.0 5.3 28.7 40.9 17.0 5.8 19.2 2.5 171.7 4.9 37.7 12.0 3.6 9.9 6.3 17.4 5.7 1.1 3.6 16.8 114.3 2.1 4.1 5.3 9.7 40.2 31.7 5.2 7.2 15.9 3.8 22.1 17.5 93.5 42.7 3.4 0.6 46.3 2.1 5.2 1.9 3.7 36.7 84.1 0.0 10.0 6.3 34.1 8.8 1.9 2.3 7.5 7.3 6.0 1.7 2.7 IDH2 ENSG00000182054 "Isocitrate dehydrogenase (NADP(+)) 2" P48735 15 90083045-90102477 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glyoxylate bypass, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "heart muscle: 492.6;skeletal muscle: 1302.3;tongue: 1611.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 732.5;Distal tubular cells: 1168.0;Extravillous trophoblasts: 586.7;Syncytiotrophoblasts: 573.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MOLT-4: 425.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007831 Enhanced Supported Mitochondria NA NA 5200000 "Cluster 51: Monocytes - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 14: REH - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA007831: AB_1851397" "unprognostic (2.45e-2)" "prognostic favorable (5.15e-5)" "unprognostic (2.92e-1)" "unprognostic (1.53e-1)" "unprognostic (3.53e-1)" "unprognostic (8.46e-2)" "unprognostic (3.83e-2)" "unprognostic (2.55e-3)" "unprognostic (1.86e-2)" "unprognostic (1.89e-2)" "unprognostic (2.76e-1)" "unprognostic (4.90e-2)" "unprognostic (2.19e-3)" "unprognostic (3.92e-3)" "unprognostic (4.46e-1)" "unprognostic (1.30e-2)" "unprognostic (2.58e-2)" 32.8 10.5 56.5 60.2 67.8 161.1 51.1 57.1 59.8 36.6 76.6 95.9 97.2 29.0 12.5 140.6 32.7 31.7 492.6 47.2 55.0 208.3 274.7 32.0 77.1 61.0 61.3 13.6 128.7 104.0 15.5 87.3 54.4 76.2 84.1 5.4 163.1 90.4 1302.3 61.8 84.3 79.8 52.9 36.8 175.7 5.3 71.6 148.7 16.0 1611.3 66.0 53.3 49.4 57.6 61.3 33.5 169.9 169.8 23.3 28.3 144.5 74.5 110.8 68.0 72.6 16.1 51.1 72.7 21.0 61.2 65.1 20.8 25.1 22.4 32.0 143.8 16.9 122.9 12.7 119.7 28.1 85.1 118.2 59.7 12.7 16.3 13.0 82.1 141.0 246.4 18.9 59.3 53.0 175.3 425.0 131.2 51.8 81.9 14.3 352.0 122.4 213.7 105.6 71.3 244.5 125.3 92.1 359.8 29.9 94.2 290.9 256.9 34.0 120.4 17.0 16.1 34.9 101.5 20.5 9.0 38.4 175.0 71.2 45.0 112.8 75.6 105.9 199.1 53.2 70.1 77.0 120.1 136.9 47.7 42.9 71.8 22.9 99.9 252.1 79.4 72.4 163.4 56.5 67.8 57.1 59.8 47.2 55.0 61.0 61.3 54.4 52.9 71.6 57.6 16.9 6.4 21.0 40.1 64.2 39.9 98.8 91.6 12.5 6.2 90.5 48.1 445.9 114.4 95.8 75.4 10.4 732.5 84.0 70.0 1168.0 252.8 5.6 96.4 25.7 41.6 61.7 193.8 11.8 288.8 586.7 44.7 88.2 50.9 31.6 29.2 38.2 283.1 263.7 10.1 8.3 158.3 229.9 77.7 101.1 3.2 14.0 79.0 58.7 5.6 85.3 20.9 119.4 16.6 27.3 116.6 105.0 35.3 185.9 170.3 69.6 205.0 167.9 5.4 13.1 60.8 73.4 0.6 15.6 113.3 67.1 573.0 88.1 14.7 305.1 140.1 IDH3A ENSG00000166411 "Isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha" P50213 15 78131498-78171945 "Citric acid cycle related proteins, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 99.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 144.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041465, HPA062971" Supported Enhanced Mitochondria No No 110000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA041465: AB_10794377, HPA062971: AB_2684913" "unprognostic (2.33e-1)" "unprognostic (1.21e-1)" "unprognostic (5.76e-3)" "unprognostic (2.26e-1)" "unprognostic (1.02e-1)" "unprognostic (4.01e-1)" "unprognostic (2.29e-1)" "unprognostic (6.47e-2)" "unprognostic (1.69e-2)" "unprognostic (2.30e-1)" "unprognostic (3.05e-1)" "unprognostic (1.42e-1)" "prognostic favorable (6.49e-8)" "unprognostic (1.40e-1)" "unprognostic (3.08e-2)" "unprognostic (4.49e-2)" "unprognostic (3.39e-2)" 22.6 25.1 11.5 19.9 12.6 9.7 9.6 17.0 14.7 12.4 21.4 26.2 36.6 13.7 7.8 17.0 11.0 9.0 62.5 14.8 13.2 16.8 14.2 11.9 17.1 13.0 13.1 10.8 13.0 54.7 6.9 12.1 15.2 13.9 26.7 26.2 16.2 16.1 79.4 15.8 36.0 17.1 10.1 15.3 11.9 16.9 14.3 35.0 11.2 99.7 24.8 17.7 11.1 14.8 43.8 58.5 10.4 36.5 25.5 26.1 22.6 50.8 24.5 40.6 30.5 41.6 25.8 91.6 36.8 29.9 59.9 64.2 98.2 39.3 37.0 40.7 32.2 35.7 62.4 19.2 21.8 69.8 48.8 19.9 23.6 39.4 41.2 19.3 25.7 32.0 46.4 35.9 26.0 41.4 51.4 17.4 12.9 25.2 21.8 29.3 44.4 28.1 33.4 58.3 41.4 15.8 58.2 82.1 47.1 19.1 32.7 37.4 26.4 47.6 43.9 63.1 83.1 41.5 99.9 48.8 33.2 64.9 37.7 16.9 27.9 8.3 15.1 52.9 16.4 27.7 14.7 13.5 43.5 32.6 15.2 16.4 15.5 17.3 54.8 144.4 17.7 23.2 11.5 12.6 17.0 14.7 14.8 13.2 13.0 13.1 15.2 10.1 14.3 14.8 18.0 9.6 16.5 22.9 30.6 56.0 58.7 51.4 33.0 35.1 10.9 12.6 17.5 14.3 22.6 25.8 37.5 38.3 63.0 69.0 82.2 26.1 52.2 19.9 13.4 17.5 19.2 9.4 45.9 17.9 40.4 21.2 11.7 9.2 27.3 14.5 10.8 22.4 26.5 26.9 53.3 37.6 69.2 24.9 28.6 23.4 20.8 26.4 26.6 12.2 16.0 29.3 12.3 19.6 17.9 21.5 37.9 23.7 33.2 40.6 49.6 48.1 38.2 34.6 13.1 23.8 25.5 45.7 26.2 28.4 41.2 68.4 17.7 37.2 56.0 42.0 IDH3B RP46 ENSG00000101365 "Isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta" O43837 20 2658395-2664219 "Citric acid cycle related proteins, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049387, HPA054180" Supported Enhanced Mitochondria NA NA 8300 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA049387: AB_2680740, HPA054180: AB_2682407" "unprognostic (1.19e-1)" "unprognostic (1.47e-1)" "unprognostic (2.12e-1)" "unprognostic (2.43e-2)" "unprognostic (3.24e-2)" "unprognostic (6.83e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (2.76e-2)" "unprognostic (2.99e-1)" "unprognostic (5.69e-2)" "unprognostic (4.75e-3)" "unprognostic (1.39e-2)" "prognostic favorable (6.78e-8)" "unprognostic (8.89e-2)" "unprognostic (4.02e-2)" "unprognostic (2.79e-1)" "unprognostic (1.16e-1)" 55.6 61.3 51.8 33.4 53.0 57.9 54.7 60.8 57.9 56.6 49.4 70.8 73.9 57.3 35.9 62.4 49.8 29.6 185.8 53.8 56.3 71.0 60.5 43.9 41.9 58.0 54.0 57.7 46.0 75.3 36.8 41.1 60.0 45.7 59.7 46.1 49.1 43.1 204.0 61.9 59.9 44.7 50.6 53.1 63.7 36.6 56.6 59.5 49.4 236.6 56.5 55.5 53.4 56.0 111.6 147.4 66.0 57.9 71.3 55.9 76.0 58.2 74.0 134.5 106.7 191.4 113.4 124.5 52.2 80.4 123.7 152.7 122.9 189.0 122.6 34.7 96.7 151.2 58.4 200.6 69.7 166.5 31.8 74.4 71.5 125.9 65.7 59.2 80.4 105.6 194.9 67.7 83.0 61.1 146.1 190.4 128.3 113.4 137.9 117.7 120.2 140.2 77.7 102.5 118.5 85.5 71.9 235.0 127.3 50.8 118.1 73.0 72.4 104.2 65.4 35.8 136.3 91.2 225.3 129.8 49.1 169.9 101.2 76.0 111.7 72.2 84.9 120.8 64.5 96.3 72.8 77.7 131.9 84.6 84.6 73.1 31.4 84.8 110.9 61.2 108.1 102.1 51.8 53.0 60.8 57.9 53.8 56.3 58.0 54.0 60.0 50.6 56.6 56.0 50.7 38.5 28.2 10.4 52.1 56.7 60.2 103.8 48.9 37.9 38.5 38.2 186.0 52.9 49.5 23.9 33.3 133.9 71.3 81.7 156.5 88.5 59.3 28.2 36.0 53.7 50.7 41.6 7.0 102.1 86.3 49.2 37.2 35.9 48.2 54.1 41.7 55.4 97.6 13.5 7.6 68.4 71.2 57.7 60.9 115.1 45.1 51.7 69.4 10.3 78.7 49.3 56.7 6.6 8.9 70.8 72.5 47.4 38.1 37.5 121.7 174.9 33.4 33.4 78.9 50.0 64.1 52.8 55.3 48.4 60.0 108.5 49.1 63.4 113.7 54.3 IFI6 "6-16, FAM14C, G1P3, IFI-6-16, IFI616" ENSG00000126709 "Interferon alpha inducible protein 6" P09912 1 27666064-27672212 "Predicted membrane proteins" "Antiviral defense, Apoptosis, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Cytotrophoblasts: 4084.0;Extravillous trophoblasts: 1291.2;Syncytiotrophoblasts: 4273.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 1349.9;BJ hTERT+ SV40 Large T+ RasG12V: 1570.7;EFO-21: 544.1;SK-MEL-30: 1075.0" "Low region specificity" "Detected in all" HPA005543 Approved Approved Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA005543: AB_1849342" "unprognostic (4.31e-1)" "unprognostic (1.03e-1)" "unprognostic (1.54e-1)" "unprognostic (1.04e-1)" "unprognostic (2.70e-1)" "unprognostic (6.96e-2)" "unprognostic (9.21e-2)" "unprognostic (1.07e-1)" "unprognostic (3.06e-1)" "unprognostic (6.77e-3)" "unprognostic (5.04e-2)" "unprognostic (1.64e-2)" "unprognostic (1.92e-3)" "unprognostic (1.81e-1)" "unprognostic (8.40e-2)" "unprognostic (3.42e-2)" "unprognostic (1.72e-2)" 84.0 161.4 117.5 37.5 142.0 113.2 73.1 106.8 159.3 99.7 164.7 76.3 44.0 55.6 39.1 30.5 49.6 56.8 114.2 126.4 168.7 154.1 135.6 143.5 14.9 200.8 145.5 81.4 57.2 116.0 316.7 298.2 155.6 60.6 24.5 17.2 334.3 23.0 23.8 35.3 52.1 43.6 299.5 91.0 96.1 61.9 153.1 62.2 166.9 20.1 14.5 43.8 47.4 139.2 15.6 4.4 22.7 14.1 72.4 38.8 90.6 48.5 220.1 1349.9 1570.7 8.0 58.5 6.1 544.1 22.1 352.4 5.2 5.5 10.8 43.7 117.3 18.4 36.4 11.2 4.8 19.4 12.4 45.1 43.3 1.8 82.1 1.1 20.9 12.6 31.6 2.5 95.2 15.3 4.4 44.1 153.4 4.4 28.7 46.4 29.6 12.1 14.9 12.2 0.9 32.2 28.8 59.9 13.6 1075.0 6.7 6.9 46.5 21.7 12.6 19.3 9.4 8.4 113.5 68.1 4.4 24.6 105.3 35.8 193.3 265.8 252.0 128.7 374.6 127.9 57.3 128.2 118.0 117.6 47.0 132.7 130.9 506.8 102.0 259.4 12.8 172.9 113.2 117.5 142.0 106.8 159.3 126.4 168.7 200.8 145.5 155.6 299.5 153.1 139.2 158.0 141.1 74.4 5.2 26.1 23.5 19.8 39.3 29.0 15.2 17.5 14.4 12.9 54.3 42.2 64.4 10.4 4084.0 44.7 13.2 19.6 244.0 3.4 61.4 76.4 194.8 58.4 27.6 3.6 340.0 1291.2 149.3 21.4 91.8 63.3 186.3 82.8 40.4 685.3 3.3 7.4 60.5 67.1 71.8 49.1 11.5 110.6 169.4 71.2 24.4 93.8 95.1 46.4 16.1 3.9 214.2 11.7 204.7 96.0 48.2 16.9 32.7 89.3 5.6 111.7 60.9 63.1 7.9 1.6 5.8 22.4 4273.1 59.6 138.6 13.0 49.0 IGSF22 "FLJ37794, IGFN2" ENSG00000179057 "Immunoglobulin superfamily member 22" Q8N9C0 11 18704312-18726230 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "skin 1: 1.0" "Cell type enhanced" "Detected in many" "Collecting duct cells: 23.9;Distal tubular cells: 21.5" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB026459, HPA037851" Uncertain Approved Mitochondria NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB026459: , HPA037851: " "unprognostic (4.05e-2)" "unprognostic (3.65e-2)" "unprognostic (2.34e-2)" "unprognostic (1.84e-1)" "unprognostic (1.23e-1)" "unprognostic (8.93e-2)" "unprognostic (1.02e-1)" "unprognostic (8.38e-2)" "unprognostic (8.70e-2)" "unprognostic (4.24e-2)" "unprognostic (1.99e-4)" "unprognostic (9.35e-2)" "unprognostic (3.72e-4)" "unprognostic (2.87e-1)" "unprognostic (2.18e-1)" "unprognostic (3.43e-1)" "unprognostic (7.94e-3)" 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.3 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.2 1.0 0.1 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.3 0.2 0.3 0.1 0.1 0.1 0.0 0.3 0.2 0.6 0.0 0.5 0.3 2.9 2.4 4.7 1.4 0.6 1.3 7.5 5.3 1.7 0.0 3.1 23.9 0.0 0.0 1.0 1.5 21.5 3.3 1.4 5.3 1.2 0.9 3.6 0.0 3.2 4.3 0.0 0.7 2.0 5.8 2.5 0.7 0.4 0.4 1.5 1.7 1.7 5.8 8.2 0.3 1.0 4.6 1.5 0.6 0.0 0.0 0.7 0.5 2.1 1.5 0.3 9.5 2.6 0.7 0.3 4.0 0.3 2.2 6.1 0.9 0.0 0.5 1.0 0.0 0.4 0.7 1.7 0.0 2.9 3.1 2.8 8.4 IL18R1 "CD218a, IL-1Rrp, IL1RRP" ENSG00000115604 "Interleukin 18 receptor 1" Q13478 2 102311529-102398777 "CD markers, Enzymes, Plasma proteins, Predicted membrane proteins" "Inflammatory response" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 24.2;lymphoid tissue: 18.5" "Cell type enhanced" "Detected in many" "dendritic cells: 44.7;granulocytes: 111.2;Langerhans cells: 25.4;NK-cells: 42.2;T-cells: 25.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 45.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 27.4;HHSteC: 35.4;U-937: 52.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA007615 Approved Approved Mitochondria Yes No "Cluster 48: NK-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" Mitochondria "HPA007615: AB_1851675" "unprognostic (3.60e-3)" "unprognostic (9.75e-3)" "unprognostic (1.12e-3)" "unprognostic (3.01e-2)" "unprognostic (2.34e-3)" "unprognostic (7.11e-2)" "unprognostic (2.95e-2)" "unprognostic (1.74e-2)" "unprognostic (3.59e-1)" "unprognostic (7.86e-2)" "unprognostic (3.40e-2)" "unprognostic (1.70e-1)" "prognostic unfavorable (4.52e-4)" "unprognostic (2.62e-1)" "unprognostic (1.62e-2)" "unprognostic (5.71e-2)" "unprognostic (2.48e-2)" 8.2 2.3 1.3 5.6 1.4 2.4 5.4 1.2 1.9 4.5 1.6 4.0 4.1 3.1 1.6 2.2 3.7 2.9 4.5 1.0 2.4 4.4 6.6 24.2 4.1 1.5 1.3 1.1 1.3 3.2 1.7 6.9 1.8 3.3 1.0 0.2 2.2 5.7 0.9 2.6 8.8 0.7 1.3 18.5 4.3 0.5 2.0 2.0 2.1 1.1 2.2 4.0 2.8 1.3 1.8 0.6 0.0 0.0 1.3 0.8 2.3 0.0 1.1 0.1 0.5 0.0 0.8 0.0 0.1 0.0 3.4 0.9 0.0 2.4 0.0 27.4 1.2 2.1 0.5 0.1 35.4 8.8 10.1 7.8 1.9 3.1 5.4 0.0 7.4 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.1 1.4 1.1 0.0 0.0 0.0 0.3 0.9 0.0 0.0 1.2 0.1 0.3 0.1 0.0 0.0 0.8 0.9 0.5 3.2 0.6 0.0 0.0 0.0 0.1 52.0 3.6 10.0 0.0 4.8 6.2 0.1 16.3 0.1 3.6 4.7 3.6 0.2 0.6 1.4 6.7 45.6 0.0 10.4 4.1 1.9 1.3 1.4 1.2 1.9 1.0 2.4 1.5 1.3 1.8 1.3 2.0 1.3 10.2 0.0 8.5 0.3 2.7 0.8 1.1 1.1 0.6 0.0 0.3 0.3 3.9 0.0 2.3 1.8 0.0 0.0 44.7 0.3 1.9 0.9 0.1 1.0 4.1 7.4 0.0 3.6 0.2 0.6 1.0 3.1 5.1 1.1 111.2 0.0 10.0 7.6 0.1 0.0 1.0 0.1 0.0 2.4 25.4 0.1 0.3 16.5 3.6 12.2 1.0 0.2 42.2 1.5 0.0 1.1 0.4 0.0 10.3 1.0 0.1 0.9 3.8 0.2 6.6 0.9 1.4 0.4 1.3 0.3 1.0 0.0 25.4 0.1 0.4 0.9 IMMP1L "FLJ25059, IMMP1" ENSG00000148950 "Inner mitochondrial membrane peptidase subunit 1" Q96LU5 11 31432401-31509645 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038372, HPA058308" Approved Enhanced Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA038372: AB_10669643, HPA058308: AB_2732620" "unprognostic (2.39e-1)" "unprognostic (1.20e-2)" "unprognostic (1.12e-1)" "unprognostic (6.17e-2)" "unprognostic (9.67e-2)" "unprognostic (2.08e-2)" "prognostic unfavorable (7.97e-4)" "unprognostic (7.59e-2)" "unprognostic (4.66e-3)" "unprognostic (5.15e-3)" "prognostic favorable (6.72e-4)" "unprognostic (1.97e-1)" "unprognostic (1.07e-2)" "unprognostic (4.66e-1)" "unprognostic (4.52e-2)" "unprognostic (1.37e-2)" "unprognostic (1.04e-3)" 11.7 15.6 42.8 6.4 43.7 11.1 19.3 45.5 66.4 13.5 41.8 12.7 8.6 11.5 29.8 11.7 10.4 5.1 26.2 42.8 42.3 27.2 18.6 8.9 9.5 42.4 42.0 17.5 16.4 17.9 23.3 6.9 42.3 14.3 10.0 37.7 11.8 14.1 50.0 12.5 9.5 10.7 42.9 10.8 15.1 16.7 43.0 24.8 13.2 42.1 13.1 10.9 12.6 43.5 22.9 26.9 95.6 21.0 14.9 9.9 15.3 19.9 8.7 16.2 11.7 21.0 17.5 20.7 18.7 15.9 32.5 25.8 37.6 28.8 23.8 24.9 52.6 29.4 45.5 32.3 15.8 29.6 19.9 8.0 27.1 8.7 19.2 29.5 17.5 48.8 38.0 23.2 15.9 28.2 48.5 48.9 15.8 114.6 26.3 41.1 72.2 20.6 54.6 26.2 22.5 27.0 32.5 11.6 32.5 61.9 37.1 35.1 2.6 15.3 27.2 16.2 42.2 17.2 58.2 47.5 24.9 24.9 18.5 21.9 3.0 32.2 28.9 3.4 26.3 34.1 25.3 29.5 8.1 32.1 32.0 39.8 0.8 37.3 3.0 40.2 35.4 13.6 42.8 43.7 45.5 66.4 42.8 42.3 42.4 42.0 42.3 42.9 43.0 43.5 29.2 35.3 14.6 30.7 22.4 18.2 26.8 60.5 12.0 30.6 44.6 55.1 56.8 18.6 26.8 60.7 33.3 36.3 17.6 21.7 119.3 17.0 39.8 30.2 16.9 19.4 56.5 47.4 40.6 24.5 32.5 19.7 20.9 33.8 22.7 22.7 18.2 45.0 21.3 43.7 48.0 30.6 52.9 7.7 11.4 10.5 13.4 9.4 8.8 24.4 10.3 85.3 30.9 51.3 60.7 15.8 26.7 20.7 22.0 26.0 18.6 98.4 28.9 38.5 32.9 19.1 51.0 61.6 23.0 19.6 27.3 23.7 24.2 16.2 34.7 26.2 IMMP2L "IMMP2L-IT1, IMP2" ENSG00000184903 "Inner mitochondrial membrane peptidase subunit 2" Q96T52 7 110662644-111562517 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Astrocytes: 247.8;Distal tubular cells: 160.4;Excitatory neurons: 365.4;Inhibitory neurons: 373.9;Microglial cells: 455.3;Oligodendrocyte precursor cells: 273.9;Oligodendrocytes: 233.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026711 Approved Approved Mitochondria NA NA "Cluster 24: B-cells - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA026711: AB_1851760" "unprognostic (2.55e-2)" "unprognostic (1.40e-2)" "unprognostic (4.29e-1)" "unprognostic (1.04e-1)" "unprognostic (3.76e-2)" "prognostic unfavorable (1.89e-5)" "unprognostic (5.64e-3)" "unprognostic (1.00e-1)" "unprognostic (4.17e-1)" "unprognostic (5.68e-3)" "unprognostic (1.12e-1)" "unprognostic (1.09e-1)" "unprognostic (2.89e-3)" "unprognostic (1.32e-1)" "unprognostic (6.65e-2)" "unprognostic (1.79e-1)" "unprognostic (2.71e-1)" 19.2 14.2 10.4 5.1 12.5 5.2 15.7 9.6 11.7 12.4 14.2 14.6 7.6 15.3 11.9 8.0 16.0 8.5 13.1 11.9 12.2 34.0 25.7 8.1 7.5 11.3 11.3 19.5 12.1 20.1 8.0 9.0 11.3 19.0 8.2 9.2 11.1 21.1 27.3 10.2 12.9 14.2 10.9 8.4 11.8 9.9 11.4 8.9 23.5 25.1 7.5 12.5 10.5 13.1 17.5 10.3 6.1 25.1 15.8 16.0 10.7 11.8 11.9 7.7 8.1 5.1 19.8 28.4 31.4 10.2 14.3 9.6 6.6 23.6 12.7 17.9 6.7 9.7 44.2 14.0 24.2 18.2 1.1 27.9 30.7 3.3 21.4 35.0 10.2 26.2 32.0 21.4 5.9 12.3 24.4 20.3 6.0 33.2 15.8 5.1 50.0 15.0 28.0 7.3 7.0 22.1 5.1 23.8 67.3 17.2 9.6 10.4 6.5 11.8 12.3 11.9 14.4 12.2 3.5 17.4 12.9 8.4 63.1 15.9 9.1 2.9 10.5 11.9 19.4 28.5 18.3 12.3 17.0 38.7 25.0 17.6 0.5 47.0 17.3 21.3 12.4 8.1 10.4 12.5 9.6 11.7 11.9 12.2 11.3 11.3 11.3 10.9 11.4 13.1 22.3 19.2 13.2 247.8 20.4 32.9 34.4 41.4 39.9 11.3 35.3 39.4 19.5 15.7 23.9 47.8 8.4 22.4 11.9 3.1 160.4 30.1 8.4 10.4 12.6 15.3 19.3 21.9 365.4 8.1 27.1 19.5 12.8 12.0 3.8 11.3 11.7 23.8 11.7 8.4 373.9 7.0 28.5 4.9 14.1 5.6 49.4 6.1 21.4 455.3 10.1 16.3 1.0 273.9 233.7 10.8 6.8 35.0 9.2 36.2 25.5 66.8 13.3 15.6 13.1 19.5 46.7 24.2 12.8 28.0 26.6 16.3 12.6 18.7 11.7 22.1 IMMT "HMP, Mic60, MICOS60, MINOS2, P87, P89" ENSG00000132305 "Inner membrane mitochondrial protein" Q16891 2 86143932-86195472 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 288.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 223.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022439, HPA036164, HPA036165" Supported Enhanced Mitochondria NA NA 220000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB022439: , HPA036164: AB_2674979, HPA036165: AB_2674980" "unprognostic (3.83e-3)" "unprognostic (1.56e-1)" "unprognostic (1.95e-2)" "prognostic unfavorable (1.06e-4)" "unprognostic (1.40e-1)" "unprognostic (2.45e-2)" "prognostic unfavorable (2.03e-4)" "unprognostic (5.66e-2)" "unprognostic (1.53e-1)" "unprognostic (8.10e-2)" "unprognostic (7.35e-2)" "unprognostic (2.21e-1)" "prognostic favorable (3.51e-6)" "unprognostic (2.06e-3)" "unprognostic (6.35e-2)" "unprognostic (1.20e-1)" "unprognostic (2.82e-1)" 41.3 82.4 30.3 34.9 31.8 40.3 36.5 33.1 39.0 30.2 41.9 57.4 57.4 35.0 27.6 43.4 30.9 27.1 174.8 31.9 34.5 80.9 65.0 32.5 44.3 35.3 34.2 28.1 48.5 90.2 36.0 36.7 35.1 29.4 58.1 42.4 37.9 35.1 200.9 38.0 46.6 38.9 29.8 44.8 56.0 49.2 32.6 52.3 35.5 288.9 47.1 41.5 33.8 32.8 115.6 111.2 99.2 45.6 93.7 88.3 101.5 80.5 85.6 108.0 98.7 160.7 89.1 175.7 78.9 87.7 87.7 83.4 128.9 118.4 131.8 71.4 105.9 139.0 65.6 192.0 95.7 135.9 91.1 100.6 84.0 101.7 119.5 67.2 124.7 99.7 138.4 96.7 105.1 99.0 135.6 140.8 117.8 175.1 88.2 89.9 211.2 158.7 122.5 128.3 119.3 89.0 82.9 124.0 126.3 77.4 70.7 94.6 93.6 76.0 83.6 112.0 101.8 76.6 104.1 119.9 86.9 158.8 94.4 12.1 29.2 12.2 23.5 34.0 20.7 15.9 20.6 19.3 32.9 13.7 18.3 22.3 3.8 20.8 33.2 17.2 23.2 25.4 30.3 31.8 33.1 39.0 31.9 34.5 35.3 34.2 35.1 29.8 32.6 32.8 29.3 54.5 49.2 31.3 42.1 23.3 34.9 51.6 30.1 40.9 21.6 19.7 223.0 24.3 57.3 40.5 33.3 94.9 49.6 57.9 133.1 59.9 152.4 26.5 34.0 38.3 56.0 76.1 41.6 52.8 73.9 36.3 39.8 26.8 48.0 55.6 35.7 64.2 70.9 23.5 46.5 46.2 38.7 49.4 28.3 158.9 27.7 48.9 17.8 26.2 80.6 30.2 52.5 29.1 44.1 43.3 36.3 36.9 56.4 28.6 59.8 92.6 41.8 42.5 6.6 39.7 58.2 100.7 54.6 41.1 24.9 98.5 45.6 118.6 68.0 33.6 ITPK1 ENSG00000100605 "Inositol-tetrakisphosphate 1-kinase" Q13572 14 92936914-93116320 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Isomerase, Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 106.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 42.9" "Group enriched" "Detected in all" 5 "granulocytes: 42.9;monocytes: 25.9" "Cell line enhanced" "Detected in all" "WM-115: 110.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055230 Approved Approved Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 45: Enterocytes - Digestion" Mitochondria "HPA055230: AB_2682748" "unprognostic (1.93e-3)" "unprognostic (2.50e-1)" "unprognostic (2.15e-1)" "prognostic favorable (8.56e-4)" "unprognostic (4.27e-1)" "unprognostic (2.04e-2)" "unprognostic (6.97e-2)" "unprognostic (1.32e-1)" "unprognostic (1.24e-2)" "unprognostic (2.86e-2)" "unprognostic (8.14e-2)" "unprognostic (2.27e-1)" "unprognostic (1.37e-3)" "unprognostic (2.39e-1)" "unprognostic (2.02e-1)" "unprognostic (4.20e-1)" "unprognostic (7.25e-3)" 60.0 27.2 88.3 15.5 105.9 17.3 45.3 84.7 92.7 57.0 57.2 60.1 44.4 66.8 11.6 24.8 30.3 19.4 59.2 92.5 80.7 35.6 48.3 31.6 9.0 90.2 95.8 27.1 30.7 14.8 20.6 6.8 83.0 38.8 16.4 9.3 21.0 21.7 40.9 22.2 58.5 23.4 83.2 38.1 34.2 29.5 100.4 6.9 25.4 16.1 6.6 62.5 35.0 100.7 28.1 56.6 10.3 26.3 22.5 12.6 27.8 11.8 17.5 22.9 13.8 32.8 48.9 17.7 57.4 18.6 8.7 32.5 29.6 50.3 7.2 65.9 13.1 39.2 14.6 28.5 16.8 17.9 41.5 8.2 29.5 11.6 26.3 9.9 22.8 18.0 21.9 19.8 11.3 74.6 15.5 25.5 22.0 36.4 25.5 29.1 15.1 26.3 15.5 46.3 28.0 35.5 29.6 59.0 49.5 7.8 79.5 21.7 18.0 15.9 17.3 27.0 18.9 19.3 19.1 11.4 14.6 13.8 110.8 5.3 9.8 18.2 3.2 15.4 1.9 3.3 2.0 2.1 7.0 1.0 1.2 2.2 42.9 2.4 25.9 3.5 3.0 5.1 88.3 105.9 84.7 92.7 92.5 80.7 90.2 95.8 83.0 83.2 100.4 100.7 11.8 12.8 11.1 32.0 10.8 7.4 7.5 8.3 2.8 10.2 11.8 7.6 24.3 17.2 5.1 29.5 18.8 9.7 12.9 73.5 13.7 19.2 12.7 18.1 12.5 12.4 28.8 5.9 45.1 27.3 10.0 8.9 13.3 21.2 16.5 9.2 13.9 31.3 19.4 6.7 21.6 24.8 4.1 44.7 11.8 30.3 14.9 30.5 26.6 16.9 23.2 17.2 18.6 31.7 46.5 44.6 38.7 48.2 13.2 15.2 106.6 23.0 3.3 13.7 19.7 7.4 17.8 4.3 14.3 7.0 4.4 6.8 12.7 10.3 34.5 11.0 JADE1 "JADE-1, PHF17" ENSG00000077684 "Jade family PHD finger 1" Q6IE81 4 128809700-128875224 "Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020016 Approved Approved Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 25: Pancreas - Digestion" "Cluster 5: NTERA-2 - Transcription" "Cluster 50: Fibroblasts - ECM organization" Mitochondria "HPA020016: AB_1855292" "unprognostic (1.91e-2)" "unprognostic (1.81e-1)" "unprognostic (4.79e-2)" "unprognostic (1.63e-2)" "unprognostic (3.19e-1)" "unprognostic (2.09e-2)" "unprognostic (7.59e-2)" "unprognostic (6.96e-3)" "unprognostic (6.93e-2)" "unprognostic (8.16e-2)" "unprognostic (9.39e-2)" "unprognostic (8.38e-3)" "prognostic favorable (8.22e-6)" "unprognostic (1.45e-2)" "unprognostic (2.58e-1)" "unprognostic (9.92e-2)" "unprognostic (1.68e-1)" 25.3 21.6 11.7 10.3 12.8 46.2 20.1 21.6 12.4 16.4 10.0 16.3 8.6 12.3 8.7 12.2 18.5 12.6 17.7 10.2 15.9 24.7 11.7 15.9 15.2 13.6 14.1 27.9 70.8 16.5 15.0 11.2 14.8 18.0 6.2 20.4 18.9 17.2 14.9 13.4 12.3 12.7 12.0 15.4 19.1 9.7 15.8 17.8 31.4 11.5 12.3 19.5 12.9 12.1 13.5 25.8 25.2 18.6 33.7 23.7 32.9 21.0 12.5 22.4 20.4 22.8 22.9 40.8 24.3 12.1 9.8 4.5 29.8 7.4 24.9 31.9 13.5 22.8 35.9 20.9 57.9 37.5 17.6 26.5 11.5 27.3 20.2 18.5 24.5 26.1 36.7 54.3 17.5 16.2 47.8 28.0 67.8 13.5 13.1 35.0 17.3 22.0 35.7 6.5 32.7 23.7 20.1 16.2 16.5 35.0 13.1 20.9 17.1 21.9 36.3 16.9 24.8 35.9 32.0 46.0 23.7 36.8 18.3 31.4 10.7 35.9 17.2 17.2 21.1 13.4 18.3 19.2 10.4 18.6 25.5 19.9 13.8 31.1 23.6 4.9 14.6 16.3 11.7 12.8 21.6 12.4 10.2 15.9 13.6 14.1 14.8 12.0 15.8 12.1 24.5 38.5 25.4 17.6 35.4 14.9 16.1 4.3 32.5 40.3 25.8 32.3 33.9 42.9 13.7 49.7 50.1 25.2 42.0 3.1 19.6 30.1 3.6 45.5 21.7 21.7 10.2 48.8 24.5 48.7 16.5 36.7 25.5 37.0 17.7 34.3 18.2 37.3 10.1 28.6 31.8 8.3 46.8 28.5 14.3 4.2 36.1 16.3 21.4 12.2 27.5 26.7 107.1 17.1 19.2 44.0 7.8 48.2 41.2 12.6 12.6 34.7 29.7 28.4 85.5 33.0 59.0 6.6 21.9 20.9 13.4 4.0 40.9 8.9 10.8 5.9 KCNAB3 "AKR6A9, KCNA3B" ENSG00000170049 "Potassium voltage-gated channel subfamily A regulatory beta subunit 3" O43448 17 7921859-7929803 "Predicted intracellular proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 14.3;retina: 12.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 29.3;Horizontal cells: 131.2;Inhibitory neurons: 40.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "REH: 13.2;SH-SY5Y: 6.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077993 Approved Mitochondria NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 14: REH - Unknown function" "Cluster 62: Horizontal cells - Visual perception" Mitochondria "HPA077993: AB_2686872" "unprognostic (3.02e-2)" "unprognostic (5.59e-2)" "unprognostic (6.95e-2)" "unprognostic (2.62e-2)" "unprognostic (6.13e-2)" "unprognostic (5.84e-4)" "unprognostic (2.19e-1)" "unprognostic (5.72e-2)" "unprognostic (8.50e-2)" "unprognostic (8.55e-2)" "unprognostic (3.27e-4)" "unprognostic (7.47e-3)" "unprognostic (3.03e-6)" "unprognostic (2.12e-1)" "unprognostic (5.00e-2)" "unprognostic (4.97e-2)" "unprognostic (9.54e-3)" 2.0 0.6 3.4 1.4 3.9 3.2 1.3 9.8 7.6 4.6 1.8 1.6 0.5 14.3 0.9 1.0 4.7 0.9 0.6 3.3 2.7 3.1 1.5 1.5 2.0 3.2 8.3 2.8 1.4 0.1 4.1 0.7 3.9 3.1 0.9 12.8 1.2 0.5 0.4 1.7 2.2 5.6 3.0 3.1 1.3 2.0 5.1 1.4 2.2 0.0 1.6 0.9 1.3 4.4 1.2 1.0 4.7 1.2 0.5 1.2 1.7 4.2 2.7 3.6 4.0 0.6 0.3 2.0 0.2 0.7 0.1 0.4 1.3 0.6 5.0 1.6 1.9 0.6 1.0 0.0 4.2 0.2 2.5 1.8 1.3 3.8 0.2 0.2 0.3 5.3 0.4 0.3 0.6 0.9 0.7 2.3 0.7 0.0 0.6 13.2 1.3 0.5 0.4 1.5 0.2 6.8 0.4 0.0 0.9 0.2 1.2 0.1 0.3 0.6 2.3 0.9 0.3 1.0 1.1 1.1 1.8 2.6 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 3.4 3.9 9.8 7.6 3.3 2.7 3.2 8.3 3.9 3.0 5.1 4.4 1.6 3.2 2.7 2.6 1.0 0.5 0.6 0.4 0.6 29.3 0.6 1.4 0.8 0.0 0.7 0.0 4.2 0.3 2.2 0.8 0.0 0.8 0.6 0.9 15.7 0.8 0.0 0.0 6.8 0.5 0.3 2.2 0.5 1.3 1.3 3.6 0.4 0.3 0.7 131.2 40.3 0.4 0.0 0.6 0.7 0.7 1.8 1.1 0.0 0.0 1.5 11.3 2.1 10.6 2.1 0.7 0.1 0.7 0.9 0.6 0.3 0.2 0.1 7.6 0.0 0.5 1.1 8.3 2.6 0.1 0.4 0.1 1.3 3.0 0.6 0.2 KCTD12 "C13orf2, KIAA1778, PFET1" ENSG00000178695 "Potassium channel tetramerization domain containing 12" Q96CX2 13 76880175-76886405 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 281.2;Endothelial cells: 192.2;Enteroendocrine cells: 386.7;Hofbauer cells: 218.9;Kupffer cells: 395.9;Macrophages: 221.3;monocytes: 206.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 3.9;myeloid DC: 3.7" "Group enriched" "Detected in many" 17 "dendritic cells: 3.7;granulocytes: 1.0;monocytes: 3.9" "Cell line enhanced" "Detected in many" "ASC diff: 111.4;HUVEC TERT2: 229.0;TIME: 186.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056987, HPA077376" Supported Approved Mitochondria NA NA 21000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" Mitochondria "HPA056987: , HPA077376: " "unprognostic (6.42e-2)" "unprognostic (2.67e-1)" "unprognostic (5.13e-1)" "unprognostic (1.04e-3)" "unprognostic (5.82e-2)" "unprognostic (3.98e-2)" "unprognostic (2.02e-1)" "unprognostic (1.32e-3)" "unprognostic (1.35e-2)" "unprognostic (1.90e-1)" "unprognostic (9.83e-3)" "unprognostic (1.23e-1)" "prognostic favorable (1.14e-4)" "unprognostic (2.11e-2)" "unprognostic (1.65e-2)" "unprognostic (1.07e-1)" "unprognostic (9.25e-2)" 76.1 27.8 21.4 55.7 20.1 12.0 52.4 27.0 20.8 44.5 12.4 39.5 22.5 51.3 17.8 38.3 75.0 55.0 22.6 26.9 27.8 31.0 13.9 58.0 39.4 36.2 33.5 47.1 12.5 25.2 6.4 83.9 31.4 14.7 42.5 3.4 20.0 18.5 16.6 22.9 28.1 65.3 37.0 64.8 28.0 26.9 31.4 18.3 16.4 37.1 33.4 39.2 17.4 34.4 1.7 1.5 15.3 0.0 111.4 52.5 4.3 6.9 1.5 4.2 5.5 0.5 0.3 0.0 3.8 18.8 4.9 53.9 6.6 66.4 3.5 1.5 35.1 0.2 38.3 0.0 4.7 18.6 0.1 21.4 21.5 2.7 48.9 8.5 229.0 13.2 0.3 0.2 53.9 1.4 8.5 0.3 7.8 16.6 7.7 0.4 7.4 19.6 17.7 0.2 4.3 7.9 17.3 0.5 2.2 18.5 1.0 12.1 186.0 2.7 4.9 0.4 14.0 2.7 0.5 0.0 42.5 4.0 16.1 0.0 3.9 0.7 0.0 2.5 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.1 1.0 0.0 1.5 1.9 0.0 0.9 21.4 20.1 27.0 20.8 26.9 27.8 36.2 33.5 31.4 37.0 31.4 34.4 281.2 25.6 8.4 2.9 7.5 40.0 2.7 11.9 28.5 4.4 11.2 27.3 21.8 4.3 16.3 97.5 14.6 3.0 30.4 19.7 17.6 6.5 3.6 4.9 44.6 192.2 386.7 6.1 4.8 0.6 90.6 80.0 12.2 3.3 7.0 53.1 61.1 2.5 218.9 0.0 11.5 71.5 12.2 395.9 75.4 11.8 157.2 221.3 51.6 45.9 206.7 4.8 7.2 0.5 0.9 0.5 15.7 44.8 7.6 4.5 0.7 7.5 72.8 1.5 26.3 153.2 32.2 1.9 7.0 16.9 34.4 4.2 5.5 24.0 46.6 1.9 KCTD18 "6530404F10Rik, FLJ31322, FLJ37818" ENSG00000155729 "Potassium channel tetramerization domain containing 18" Q6PI47 2 200488958-200519784 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045498, HPA058028" Approved Approved Mitochondria NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 51: Myeloid cells - Hemostasis" Mitochondria "HPA045498: AB_10959387, HPA058028: AB_2683583" "unprognostic (2.90e-1)" "unprognostic (1.81e-1)" "unprognostic (1.57e-1)" "unprognostic (2.55e-1)" "unprognostic (4.01e-1)" "unprognostic (3.64e-2)" "unprognostic (1.02e-1)" "unprognostic (2.16e-1)" "unprognostic (2.76e-2)" "unprognostic (2.40e-2)" "unprognostic (1.18e-2)" "unprognostic (5.21e-1)" "unprognostic (1.81e-1)" "unprognostic (2.04e-1)" "unprognostic (6.58e-2)" "unprognostic (1.05e-2)" "unprognostic (1.31e-1)" 9.9 8.9 8.2 7.6 9.6 9.8 10.2 8.9 9.9 8.4 9.0 10.1 8.7 8.5 8.2 9.0 8.8 7.2 8.4 7.8 8.5 9.9 10.0 8.5 11.0 9.1 9.1 10.4 11.9 10.4 6.3 6.2 9.3 11.1 8.4 5.6 10.6 9.4 10.6 9.2 7.9 7.7 9.0 10.2 9.3 7.2 8.7 10.6 13.8 8.9 11.0 9.8 8.0 9.4 10.2 9.3 4.5 16.9 21.2 26.2 11.6 12.3 15.4 7.7 10.1 7.5 11.4 7.1 9.1 12.4 12.6 9.6 4.5 14.8 9.8 17.3 4.9 10.2 6.7 5.3 14.4 8.4 11.6 17.6 27.4 8.9 16.9 17.9 6.7 10.5 7.1 9.5 13.9 10.5 18.2 8.2 2.5 8.7 8.3 12.5 10.2 8.4 10.1 10.0 5.1 7.1 9.7 8.2 15.1 9.7 10.9 13.4 11.4 15.7 3.6 8.0 5.9 18.1 14.0 8.0 18.0 8.8 11.3 7.8 3.2 6.4 3.2 4.7 4.9 4.0 4.1 4.8 3.4 4.0 5.1 5.1 2.5 4.6 3.2 4.1 5.0 3.2 8.2 9.6 8.9 9.9 7.8 8.5 9.1 9.1 9.3 9.0 8.7 9.4 7.8 6.4 9.4 7.2 11.3 4.5 5.9 5.7 10.8 7.2 9.1 6.9 6.2 8.6 6.5 3.7 0.0 8.0 10.8 5.6 1.9 7.2 22.7 8.8 7.3 5.7 1.2 3.4 10.1 8.4 7.8 8.6 8.2 5.3 2.5 11.8 8.6 9.4 7.2 10.1 9.5 8.4 6.1 11.4 6.6 4.2 11.8 11.2 7.2 6.5 16.7 11.1 18.6 6.6 18.3 6.5 7.4 12.4 7.5 5.8 8.5 13.5 9.8 10.5 19.7 12.2 7.9 19.0 16.5 12.8 4.0 5.1 10.1 11.0 7.3 4.0 KIF16B "C20orf23, dJ971B4.1, FLJ20135, SNX23" ENSG00000089177 "Kinesin family member 16B" Q96L93 20 16272104-16573448 "Predicted intracellular proteins" Transport "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 94.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SK-BR-3: 38.1" "Low region specificity" "Detected in all" HPA051198 Approved Uncertain Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA051198: AB_2681385" "unprognostic (3.33e-1)" "unprognostic (1.74e-1)" "unprognostic (6.18e-2)" "unprognostic (2.09e-1)" "unprognostic (3.92e-2)" "unprognostic (2.44e-1)" "unprognostic (6.32e-3)" "unprognostic (7.85e-2)" "unprognostic (2.38e-1)" "unprognostic (5.34e-2)" "unprognostic (3.95e-2)" "unprognostic (5.52e-1)" "prognostic favorable (7.61e-6)" "unprognostic (4.04e-2)" "unprognostic (2.78e-1)" "unprognostic (4.74e-2)" "unprognostic (1.61e-2)" 10.1 27.4 5.4 6.4 6.1 5.9 15.8 4.9 8.6 6.3 3.6 24.5 16.7 6.1 12.5 9.4 5.1 8.3 11.5 4.3 6.4 18.1 11.7 8.8 5.3 6.4 5.4 12.8 6.5 31.5 5.2 4.8 6.0 7.3 19.1 9.7 7.3 10.8 17.1 11.9 20.8 7.4 3.9 8.2 12.8 5.1 6.3 5.9 11.1 13.1 4.7 7.9 6.2 7.9 7.7 19.3 9.1 8.3 6.8 5.0 8.8 7.4 4.5 4.6 5.0 9.5 18.5 10.7 4.7 8.0 12.7 6.9 10.8 11.0 6.8 5.7 6.2 4.8 4.7 17.6 4.2 0.0 10.5 8.0 21.4 5.5 10.6 7.0 1.8 8.1 8.7 0.0 7.5 12.2 0.1 2.0 2.6 24.9 8.7 8.1 7.2 18.9 7.2 12.2 4.0 7.9 8.0 38.1 23.9 10.7 11.3 6.3 3.7 7.0 5.9 11.4 3.4 0.0 4.9 3.2 6.6 3.2 14.3 0.0 2.1 0.5 2.0 1.7 2.7 2.7 2.2 1.5 3.4 2.6 2.3 1.7 0.2 4.5 1.8 1.6 1.6 1.7 5.4 6.1 4.9 8.6 4.3 6.4 6.4 5.4 6.0 3.9 6.3 7.9 13.1 19.2 31.7 54.9 9.8 19.1 16.1 11.0 37.5 8.7 30.5 16.0 29.2 4.3 14.8 5.5 18.8 15.7 7.7 60.6 3.9 6.5 12.6 13.2 14.2 13.6 23.4 5.0 67.6 12.3 5.5 15.1 18.3 20.8 9.5 13.6 12.5 15.9 19.1 37.0 84.2 38.9 4.1 12.2 35.7 9.8 11.5 19.8 10.6 59.0 4.9 8.6 10.3 60.3 94.1 13.3 40.9 14.7 6.9 11.1 36.8 21.1 11.6 11.5 6.6 22.7 13.4 12.9 15.0 26.3 22.4 37.5 9.4 12.9 24.8 19.3 L2HGDH "C14orf160, FLJ12618" ENSG00000087299 "L-2-hydroxyglutarate dehydrogenase" Q9H9P8 14 50237563-50312229 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 56.3;Excitatory neurons: 60.5;Inhibitory neurons: 61.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065409, HPA069708" Approved Enhanced Mitochondria NA NA "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 36: HEL - Hemostasis" "Cluster 9: Photoreceptor cells - Phototransduction" Mitochondria "HPA065409: AB_2685485, HPA069708: AB_2686179" "unprognostic (1.74e-1)" "unprognostic (1.15e-2)" "unprognostic (1.13e-2)" "unprognostic (1.23e-3)" "unprognostic (1.04e-2)" "unprognostic (4.33e-2)" "unprognostic (8.84e-2)" "unprognostic (1.58e-2)" "unprognostic (4.17e-2)" "unprognostic (9.91e-2)" "unprognostic (2.84e-1)" "unprognostic (1.97e-1)" "prognostic favorable (9.75e-10)" "unprognostic (1.24e-2)" "unprognostic (5.88e-2)" "unprognostic (1.45e-1)" "unprognostic (1.02e-2)" 4.6 2.5 2.9 2.2 2.9 2.7 3.7 6.1 5.5 2.3 1.3 4.3 4.7 2.4 3.0 5.1 3.1 2.0 5.2 2.7 2.5 19.6 12.6 1.8 2.6 1.2 2.4 2.5 3.9 6.1 2.3 1.7 1.1 3.3 5.0 11.4 2.8 3.2 15.5 5.1 3.6 2.5 1.2 1.3 4.3 3.9 2.4 3.0 4.8 14.7 3.4 2.4 2.3 4.1 24.3 16.6 6.8 6.6 3.3 2.2 19.1 7.9 4.4 12.2 14.3 26.8 10.8 19.0 9.0 3.2 9.7 17.4 20.6 8.2 13.5 15.2 11.9 41.1 10.9 3.7 3.1 14.7 13.7 2.0 5.2 8.1 7.0 3.1 5.3 19.3 14.7 11.6 3.2 29.0 16.7 6.7 9.9 20.6 17.6 15.6 22.0 14.8 11.4 28.0 13.8 9.9 23.3 17.5 10.4 9.0 22.9 4.0 5.0 7.7 21.5 9.0 10.6 10.5 25.6 26.3 4.3 7.3 8.8 8.6 0.4 0.9 0.9 0.1 2.2 0.8 1.1 1.0 0.6 0.6 1.3 1.7 0.5 1.7 0.1 1.0 1.6 0.5 2.9 2.9 6.1 5.5 2.7 2.5 1.2 2.4 1.1 1.2 2.4 4.1 1.9 41.7 19.2 16.6 5.1 3.7 2.7 2.1 8.6 15.5 3.9 2.2 14.7 2.8 20.4 12.9 56.3 6.4 6.1 4.8 15.6 3.8 35.1 5.2 2.8 4.6 7.8 7.4 60.5 4.2 6.6 5.3 7.7 5.6 18.9 6.0 2.9 14.2 2.1 11.8 61.4 4.3 0.0 2.7 0.6 8.8 2.5 3.3 1.8 13.1 2.4 6.1 7.2 20.6 18.9 2.5 3.6 4.5 3.3 2.7 6.0 21.7 18.4 40.3 0.0 5.8 3.9 14.3 12.6 10.5 6.3 4.9 5.0 4.6 7.6 2.1 LACTB "FLJ14902, MRPL56" ENSG00000103642 "Lactamase beta" P83111 15 63121833-63142061 "Enzymes, Predicted intracellular proteins" "Lipid metabolism" "Hydrolase, Protease" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 152.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036361, HPA036362" Supported Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 3: Monocytes - Immune response regulation" Mitochondria "HPA036361: AB_10672244, HPA036362: AB_10670798" "unprognostic (6.07e-2)" "unprognostic (2.02e-1)" "unprognostic (2.22e-2)" "unprognostic (2.87e-1)" "unprognostic (1.20e-2)" "unprognostic (3.10e-2)" "unprognostic (8.08e-2)" "unprognostic (6.25e-2)" "unprognostic (8.98e-2)" "unprognostic (3.08e-1)" "unprognostic (6.22e-3)" "unprognostic (5.16e-3)" "unprognostic (6.28e-2)" "unprognostic (3.24e-1)" "unprognostic (8.64e-2)" "unprognostic (7.90e-2)" "unprognostic (3.88e-3)" 17.3 25.4 7.1 21.2 7.4 57.0 12.5 7.2 8.0 8.4 10.8 18.5 19.6 7.6 8.4 14.9 7.0 14.3 22.2 7.2 7.3 23.6 42.4 19.0 19.8 7.3 7.5 8.1 10.6 9.9 6.7 11.8 7.4 9.2 15.9 4.7 9.9 6.8 49.2 12.0 16.9 9.0 7.2 18.3 12.8 22.1 8.3 9.1 9.3 36.3 13.2 19.7 9.2 8.4 60.3 37.0 10.4 7.3 51.9 27.4 8.7 25.7 39.4 43.3 79.9 9.3 37.5 8.0 31.0 37.5 46.9 16.6 35.6 16.7 54.2 55.1 8.9 15.6 12.2 23.7 48.0 14.2 26.1 37.3 35.1 44.5 36.4 64.9 45.2 46.4 14.9 22.1 74.7 22.6 10.9 17.3 15.6 36.7 11.7 8.0 26.6 18.5 23.6 92.5 9.3 4.4 18.6 20.7 59.0 36.0 15.9 23.4 81.5 57.8 44.8 26.2 32.9 23.3 21.8 2.2 44.3 39.2 27.3 4.4 8.4 4.4 1.1 8.3 1.8 3.1 0.9 0.9 9.8 2.6 0.8 1.4 5.3 2.1 7.3 0.8 3.0 2.2 7.1 7.4 7.2 8.0 7.2 7.3 7.3 7.5 7.4 7.2 8.3 8.4 24.6 25.6 22.6 4.9 25.7 58.2 27.2 12.0 19.9 6.5 21.7 16.1 42.5 22.8 10.9 12.9 12.5 15.8 19.3 26.0 25.4 56.0 62.9 13.2 16.4 31.1 7.3 10.8 12.5 43.1 40.5 26.4 17.3 19.3 66.5 12.1 8.9 57.0 88.6 8.4 14.5 27.1 16.2 71.3 72.5 30.6 14.3 97.0 26.6 15.9 152.9 6.9 7.2 10.1 8.1 75.0 19.0 16.1 21.3 35.6 25.2 79.2 9.2 11.3 6.6 37.9 31.5 122.9 25.6 26.3 60.0 18.1 21.8 23.9 20.4 39.6 LANCL3 FLJ42925 ENSG00000147036 "LanC like 3" Q6ZV70 X 37571569-37684463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 8.8;Inhibitory neurons: 20.4;Squamous epithelial cells: 10.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "basophil: 3.8" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.8" "Cell line enhanced" "Detected in some" "HEL: 11.8;HMC-1: 3.6;K-562: 3.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005470, HPA076575" Approved Approved Mitochondria NA NA "Cluster 38: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA005470: AB_2134886, HPA076575: AB_2732315" "unprognostic (6.76e-2)" "unprognostic (4.21e-2)" "unprognostic (1.52e-1)" "unprognostic (1.85e-1)" "unprognostic (5.20e-2)" "unprognostic (5.26e-2)" "unprognostic (3.60e-1)" "unprognostic (1.21e-3)" "unprognostic (1.22e-1)" "unprognostic (7.11e-2)" "unprognostic (2.81e-2)" "unprognostic (2.88e-1)" "unprognostic (7.90e-5)" "unprognostic (4.01e-3)" "unprognostic (7.93e-3)" "unprognostic (1.11e-2)" "unprognostic (2.08e-2)" 0.2 0.2 0.1 0.1 0.4 0.2 0.1 2.6 1.0 0.4 0.0 1.0 0.1 0.2 0.0 1.5 0.1 0.1 0.1 0.6 3.7 0.2 0.0 0.3 0.1 1.0 1.6 0.0 0.0 0.0 0.5 0.0 1.0 0.1 0.5 0.6 0.4 0.2 0.2 0.7 0.2 0.1 0.5 0.1 0.6 0.2 2.5 0.1 0.1 0.1 0.2 0.3 1.1 0.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.7 1.5 0.2 0.0 0.0 0.2 11.8 1.1 0.0 0.0 0.0 3.6 0.0 0.3 0.0 0.0 0.0 0.2 0.0 3.0 0.0 0.6 0.0 0.1 0.2 0.2 0.1 1.1 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.8 0.0 0.0 1.1 0.5 0.0 0.0 1.8 0.0 0.3 3.8 0.0 0.2 0.4 0.0 0.3 0.0 0.1 0.8 0.0 0.0 0.0 0.4 0.1 0.4 0.0 0.0 0.3 0.3 0.1 0.4 2.6 1.0 0.6 3.7 1.0 1.6 1.0 0.5 2.5 0.5 1.3 3.2 4.1 2.9 0.1 8.8 1.2 1.8 6.8 0.8 0.6 0.4 0.9 0.0 1.2 0.0 0.0 0.0 3.0 6.6 0.0 0.0 0.1 0.3 0.6 1.1 1.8 0.8 3.1 0.2 0.2 0.4 4.1 0.7 1.3 0.1 0.0 0.2 0.1 3.3 20.4 0.4 2.0 0.3 0.5 0.0 0.3 0.2 0.0 1.0 0.2 0.5 4.1 1.0 2.0 2.1 1.4 1.5 0.2 0.7 1.6 0.2 0.0 1.4 0.0 1.8 0.9 0.7 3.1 10.1 4.4 0.1 1.4 0.2 1.0 2.5 LETM1 SLC55A1 ENSG00000168924 "Leucine zipper and EF-hand containing transmembrane protein 1" O95202 4 1811479-1856156 "Human disease related genes, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 116.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011029, HPA011100" Supported Supported Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA011029: AB_1852804, HPA011100: AB_1852802" "unprognostic (1.16e-1)" "unprognostic (1.80e-1)" "unprognostic (3.85e-2)" "unprognostic (5.04e-2)" "unprognostic (5.48e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (1.79e-4)" "unprognostic (1.37e-3)" "unprognostic (1.87e-1)" "unprognostic (3.29e-1)" "unprognostic (1.80e-1)" "prognostic unfavorable (1.77e-4)" "prognostic favorable (8.90e-4)" "unprognostic (8.06e-3)" "unprognostic (3.24e-1)" "unprognostic (1.57e-2)" "unprognostic (2.42e-1)" 13.6 16.3 14.3 7.9 13.7 7.7 10.8 11.7 14.6 8.2 10.8 20.3 13.9 8.4 3.2 23.8 8.0 4.5 19.6 13.4 13.2 13.3 16.4 8.9 7.0 12.7 13.5 9.2 12.5 11.4 8.8 4.9 11.9 8.4 10.7 4.5 9.6 4.2 18.7 15.9 11.7 5.1 12.2 10.7 13.8 14.5 15.0 25.7 10.7 10.9 7.9 8.4 10.6 11.6 22.9 38.1 11.6 36.1 17.4 12.2 20.7 22.1 10.7 21.8 16.9 35.5 24.7 37.5 15.4 23.3 34.0 22.7 29.8 31.2 13.2 25.1 31.1 38.4 30.9 25.6 22.6 39.3 30.3 19.9 22.0 24.9 21.8 10.1 19.0 22.6 51.5 22.9 15.3 25.1 57.3 44.7 30.5 24.7 43.2 32.4 16.2 21.9 17.0 31.3 29.5 26.0 25.2 31.5 13.3 10.0 29.7 20.3 28.8 24.8 14.8 21.1 37.3 19.8 32.7 29.3 22.0 33.8 20.2 3.9 3.7 2.0 5.8 5.0 5.7 4.2 4.9 4.9 4.1 3.6 3.2 4.6 0.5 5.9 5.1 12.9 4.2 2.1 14.3 13.7 11.7 14.6 13.4 13.2 12.7 13.5 11.9 12.2 15.0 11.6 12.2 16.0 11.5 15.0 19.2 40.0 40.7 13.4 8.0 19.4 19.7 10.5 23.3 11.5 14.0 27.6 33.3 17.5 24.9 116.1 31.3 25.5 32.2 9.1 19.4 16.7 15.6 20.4 14.3 31.3 22.6 17.0 32.1 14.7 10.2 17.9 16.1 33.3 21.5 15.2 12.4 29.5 12.2 18.4 19.8 45.1 20.2 13.0 19.6 4.7 13.9 12.7 28.8 9.5 13.2 42.4 52.7 16.6 17.8 58.8 48.8 46.1 5.6 28.4 13.1 23.8 16.1 54.2 44.4 25.2 51.1 15.2 16.7 21.9 53.2 48.4 LINGO3 "LERN2, LRRN6B" ENSG00000220008 "Leucine rich repeat and Ig domain containing 3" P0C6S8 19 2289784-2292024 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 34.1" "Group enriched" "Detected in some" 5 "Bipolar cells: 39.5;Oligodendrocyte precursor cells: 17.1" "Cancer enhanced" "Detected in some" "glioma: 1.4" "Region enhanced" "Detected in all" "basal ganglia: 34.1" "Group enriched" "Detected in some" 5 "basophil: 1.3;eosinophil: 4.0;neutrophil: 1.4" "Lineage enriched" "Detected in single" 9 "granulocytes: 4.0" "Group enriched" "Detected in some" 5 "HMC-1: 17.4;RPMI-8226: 4.5" "Region enhanced" "Detected in all" "basal ganglia: 59.6" "Group enriched" "Detected in many" 8 "basal ganglia: 28.8;cerebellum: 19.6;hippocampal formation: 8.4" "HPA043781, HPA059558" Enhanced Approved Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 56: Bipolar cells - Visual perception" Mitochondria "HPA043781: AB_2678668, HPA059558: AB_2684062" "unprognostic (1.24e-1)" "unprognostic (1.00e-1)" "unprognostic (7.16e-3)" "unprognostic (3.10e-1)" "unprognostic (1.59e-1)" "unprognostic (3.61e-3)" "unprognostic (3.53e-1)" "unprognostic (7.45e-3)" "unprognostic (1.11e-2)" "unprognostic (3.19e-2)" "unprognostic (4.03e-4)" "unprognostic (2.35e-2)" "unprognostic (1.36e-2)" "unprognostic (1.79e-1)" "unprognostic (5.74e-2)" "unprognostic (1.05e-1)" "unprognostic (4.14e-2)" 0.3 0.2 4.6 1.2 34.1 1.1 0.2 9.3 14.4 0.2 0.0 0.6 0.2 0.3 0.0 0.3 0.3 0.0 0.1 4.6 1.2 0.2 0.2 0.9 1.1 5.1 1.8 0.1 0.2 0.0 0.4 0.0 4.1 0.4 0.0 0.6 0.3 0.0 0.1 0.2 5.0 0.0 2.6 6.3 0.5 0.4 7.6 0.0 0.3 0.0 0.0 0.4 0.2 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.0 2.0 17.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 2.4 0.2 0.0 0.1 1.7 0.0 4.5 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 1.3 0.0 4.0 0.1 0.0 0.2 0.3 0.0 0.1 0.0 0.4 0.0 0.0 1.4 0.1 0.0 0.0 0.3 0.0 4.6 34.1 9.3 14.4 4.6 1.2 5.1 1.8 4.1 2.6 7.6 2.7 0.0 0.0 0.0 1.6 3.1 0.1 0.0 0.0 0.0 39.5 0.2 0.6 0.7 0.0 0.0 0.0 4.2 0.0 2.0 0.0 0.0 0.1 0.4 0.0 0.0 0.3 0.0 0.4 5.1 0.0 0.2 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.2 3.3 3.0 0.0 0.0 2.2 0.6 0.0 0.0 0.8 0.0 1.9 1.3 0.1 5.2 17.1 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.9 1.1 0.0 0.0 0.0 1.0 0.0 0.2 0.0 LRPPRC "GP130, LRP130, LSFC" ENSG00000138095 "Leucine rich pentatricopeptide repeat containing" P42704 2 43886224-43995989 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA transport, Transcription, Transcription regulation, Transport" "DNA-binding, RNA-binding" "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033786, HPA036408, HPA036409" Enhanced Enhanced Mitochondria No No 210000 "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB033786: AB_2137450, HPA036408: AB_10670438, HPA036409: AB_2675108" "unprognostic (1.49e-1)" "unprognostic (1.30e-1)" "unprognostic (1.61e-3)" "prognostic unfavorable (1.72e-5)" "unprognostic (1.68e-1)" "unprognostic (8.34e-3)" "prognostic unfavorable (2.31e-7)" "unprognostic (1.02e-1)" "unprognostic (1.25e-1)" "unprognostic (1.11e-1)" "unprognostic (2.44e-3)" "unprognostic (7.68e-2)" "prognostic favorable (6.65e-6)" "unprognostic (9.07e-2)" "unprognostic (1.92e-1)" "unprognostic (1.12e-1)" "unprognostic (5.00e-2)" 32.2 33.2 30.1 23.8 31.3 49.6 41.6 39.3 35.4 23.9 49.2 50.6 33.4 32.5 28.4 28.4 27.6 18.2 47.0 30.8 31.8 63.5 48.3 19.6 31.2 33.0 30.4 34.1 30.4 48.7 19.2 27.2 35.2 27.7 48.9 40.4 27.8 25.3 100.9 30.2 30.3 27.6 30.2 24.3 27.1 33.2 32.1 29.3 31.2 93.5 31.7 27.0 22.5 36.3 127.8 101.9 62.3 80.0 58.1 79.9 108.0 82.7 59.4 88.0 67.3 164.4 65.7 181.7 78.4 50.8 58.8 105.2 118.8 86.3 116.8 110.2 75.2 164.2 76.5 217.9 85.5 239.9 71.4 77.3 73.8 81.6 130.4 49.2 71.2 53.6 246.5 71.5 75.8 68.5 126.8 273.7 104.0 123.8 71.8 139.7 140.7 147.6 95.3 115.3 111.0 107.3 93.6 120.6 154.5 79.2 90.1 140.6 62.6 63.2 86.4 66.9 89.2 72.5 87.4 156.2 60.0 144.1 55.6 10.5 16.5 2.9 13.3 16.2 25.5 22.5 18.0 17.9 23.5 24.5 24.8 21.9 1.2 20.3 18.9 9.6 16.3 20.2 30.1 31.3 39.3 35.4 30.8 31.8 33.0 30.4 35.2 30.2 32.1 36.3 29.2 22.4 34.1 56.8 46.2 46.3 27.2 34.6 46.1 66.4 37.6 30.4 97.2 32.9 35.4 46.0 31.3 37.1 22.5 33.1 21.5 25.6 5.3 31.2 48.2 30.4 27.5 58.4 91.6 17.7 23.6 32.4 40.2 40.1 29.2 51.0 22.1 55.1 25.2 65.6 96.5 49.2 20.3 38.8 25.9 6.3 25.1 28.9 21.4 38.4 36.8 24.5 23.7 55.3 94.9 20.0 33.0 23.7 34.4 31.9 36.6 62.3 25.8 57.0 13.1 45.8 32.6 27.2 33.3 53.9 44.3 33.2 32.2 63.7 76.0 31.9 LRRIQ4 LRRC64 ENSG00000188306 "Leucine rich repeats and IQ motif containing 4" A6NIV6 3 169821922-169837775 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 2.9" "Group enriched" "Detected in some" 17 "Early spermatids: 42.8;Late spermatids: 27.0" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RT4: 1.6;T-47d: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA036271, HPA036706" Uncertain Approved Mitochondria NA NA "Cluster 45: Intestine - Brush border" "Cluster 6: T47d - Mammary gland" "Cluster 29: Early spermatids - Spermatogenesis" Mitochondria "HPA036271: , HPA036706: AB_2675264" "unprognostic (5.09e-2)" "unprognostic (8.85e-2)" "unprognostic (2.55e-1)" "unprognostic (1.30e-4)" "unprognostic (5.26e-3)" "unprognostic (2.32e-2)" "unprognostic (2.04e-1)" "unprognostic (2.31e-1)" "unprognostic (1.29e-1)" "unprognostic (1.17e-1)" "unprognostic (9.72e-2)" "unprognostic (1.42e-1)" "unprognostic (2.12e-1)" "unprognostic (7.47e-2)" "unprognostic (1.55e-1)" "unprognostic (6.74e-2)" "unprognostic (4.56e-3)" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 2.9 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.6 0.1 0.0 0.5 0.0 0.2 0.0 0.1 0.7 0.0 0.9 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.2 0.3 0.0 0.0 0.0 1.6 0.6 0.2 0.0 0.1 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 42.8 0.3 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 27.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.3 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 MACC1 "7A5, SH3BP4L" ENSG00000183742 "MET transcriptional regulator MACC1" Q6ZN28 7 20134655-20217404 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Growth factor, Mitogen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 11.7" "Cell type enhanced" "Detected in many" "Club cells: 102.4;Glandular and luminal cells: 100.5;Pancreatic endocrine cells: 136.4;Respiratory ciliated cells: 93.4;Urothelial cells: 238.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 98.0;CAPAN-2: 22.2;HaCaT: 66.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA020081, HPA020103, HPA029476, CAB068194" Supported Approved Mitochondria NA NA "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Mitochondria "CAB068194: AB_2665682, HPA020081: AB_1844386, HPA020103: AB_1844387, HPA029476: AB_10610136" "unprognostic (1.59e-2)" "unprognostic (1.88e-1)" "unprognostic (3.43e-2)" "prognostic unfavorable (1.56e-5)" "unprognostic (2.26e-1)" "unprognostic (1.42e-2)" "unprognostic (7.01e-2)" "unprognostic (2.52e-2)" "unprognostic (2.05e-1)" "unprognostic (2.43e-2)" "unprognostic (2.43e-3)" "unprognostic (1.03e-1)" "prognostic favorable (5.71e-9)" "unprognostic (4.49e-2)" "unprognostic (2.91e-1)" "unprognostic (1.78e-1)" "unprognostic (6.93e-3)" 0.6 2.3 1.4 1.3 0.6 1.0 4.3 1.0 1.4 2.9 0.0 2.7 9.8 0.8 0.7 8.8 0.9 2.9 0.2 1.0 0.3 6.6 0.4 5.4 0.9 1.1 0.7 0.1 3.3 0.4 0.3 0.2 1.4 1.0 3.2 0.6 5.6 2.6 0.1 2.9 11.7 0.3 0.2 0.8 4.9 0.5 0.9 0.6 1.1 0.0 3.5 3.9 3.0 1.3 98.0 0.4 0.4 0.0 0.1 0.2 0.9 0.1 0.0 0.0 0.0 21.6 22.2 13.8 1.0 0.0 0.1 66.9 0.2 0.9 0.0 0.1 0.4 13.0 0.3 0.0 0.0 5.5 0.4 0.0 0.7 0.0 0.1 0.2 0.1 0.3 14.2 6.5 0.1 8.1 0.0 1.4 1.0 19.1 0.1 0.0 0.6 10.5 16.5 6.7 0.3 0.5 0.0 7.5 0.1 0.4 3.9 0.2 0.4 0.2 0.2 0.1 0.2 20.1 1.0 5.0 0.1 0.7 0.2 0.2 0.1 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.2 0.1 0.0 0.1 1.4 0.6 1.0 1.4 1.0 0.3 1.1 0.7 1.4 0.2 0.9 1.3 4.1 70.5 57.4 0.7 6.5 2.8 75.8 11.3 2.8 3.3 22.2 7.5 0.6 24.3 102.4 40.5 2.1 0.8 2.2 16.9 7.9 51.4 2.9 59.6 16.3 4.1 38.7 4.2 1.0 63.8 0.2 5.7 18.3 100.5 12.6 0.4 2.2 0.8 4.4 1.7 2.9 19.5 34.6 0.9 3.8 1.2 2.1 11.0 1.8 0.0 8.4 0.3 1.0 0.0 0.9 136.4 20.4 2.6 6.3 72.8 40.2 17.5 93.4 1.3 0.0 0.8 3.6 0.4 0.6 13.2 4.0 0.3 2.9 0.3 17.5 238.8 MAIP1 "C2orf47, DKFZp666A212, FLJ22555" ENSG00000162972 "Matrix AAA peptidase interacting protein 1" Q8WWC4 2 199955317-200008540 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 30.0;Distal tubular cells: 37.2;Ductal cells: 31.4;Exocrine glandular cells: 28.0;Extravillous trophoblasts: 33.8;Proximal tubular cells: 84.2;Syncytiotrophoblasts: 32.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064013, HPA072231" Approved Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA064013: AB_2685175, HPA072231: AB_2732196" "unprognostic (4.89e-2)" "unprognostic (7.36e-2)" "unprognostic (7.40e-3)" "prognostic unfavorable (2.14e-4)" "unprognostic (2.74e-1)" "prognostic unfavorable (3.81e-4)" "unprognostic (4.86e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (1.87e-4)" "unprognostic (1.02e-3)" "unprognostic (7.03e-2)" "unprognostic (2.00e-2)" "unprognostic (5.21e-3)" "unprognostic (1.45e-1)" "unprognostic (1.94e-1)" "unprognostic (1.63e-1)" "unprognostic (2.70e-2)" 11.1 16.1 7.0 8.3 7.2 18.7 11.3 10.1 8.4 7.3 6.5 14.4 21.1 7.8 7.4 11.7 9.0 8.1 16.6 7.5 6.5 31.1 46.2 7.4 8.8 6.7 6.5 7.5 10.3 12.2 5.8 9.3 7.3 9.1 13.1 7.2 9.6 9.0 22.2 9.7 16.8 7.5 7.1 8.5 12.6 4.9 6.8 9.3 9.7 16.8 10.4 9.2 8.2 8.6 23.9 21.8 19.3 15.2 16.8 16.9 44.5 21.1 20.2 30.7 29.3 59.5 21.0 15.7 29.6 14.6 25.4 25.8 28.7 22.7 28.8 24.7 32.9 26.4 18.5 54.7 22.6 36.7 18.0 18.1 18.3 20.3 21.9 17.6 19.7 29.9 35.2 19.8 20.2 31.4 27.8 34.0 24.7 25.2 51.6 26.4 22.9 31.6 36.6 30.5 21.8 15.1 21.7 24.4 40.1 24.3 21.6 22.1 17.6 17.9 25.6 15.6 23.7 18.8 23.6 33.7 27.0 21.1 18.7 9.9 12.9 9.4 10.8 12.8 13.3 13.8 10.6 7.7 16.8 14.1 10.0 8.6 2.0 8.9 12.6 13.5 13.9 8.2 7.0 7.2 10.1 8.4 7.5 6.5 6.7 6.5 7.3 7.1 6.8 8.6 11.7 9.6 14.9 0.0 2.1 0.0 0.0 0.0 0.0 0.0 10.8 14.1 0.0 0.0 5.0 3.7 0.0 30.0 7.0 0.0 37.2 31.4 0.0 10.0 10.2 6.1 0.0 0.0 0.0 28.0 33.8 6.2 0.0 11.9 3.8 12.2 0.0 0.0 23.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 6.7 0.0 0.0 0.0 0.0 21.2 0.0 0.0 1.3 0.0 0.0 84.2 5.8 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 32.0 4.0 18.3 0.0 0.0 MALSU1 "C7orf30, mtRsfA" ENSG00000156928 "Mitochondrial assembly of ribosomal large subunit 1" Q96EH3 7 23298739-23311729 "Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "AN3-CA: 47.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020487, HPA052210" Approved Enhanced Mitochondria "Intracellular and membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA020487: AB_1845757, HPA052210: AB_2681762" "unprognostic (3.62e-1)" "unprognostic (3.68e-1)" "unprognostic (1.43e-1)" "unprognostic (4.66e-3)" "unprognostic (5.24e-3)" "prognostic unfavorable (9.71e-4)" "unprognostic (1.08e-1)" "unprognostic (1.51e-2)" "unprognostic (9.79e-2)" "unprognostic (1.83e-3)" "unprognostic (3.15e-2)" "unprognostic (7.15e-2)" "unprognostic (2.37e-2)" "unprognostic (1.25e-1)" "unprognostic (1.43e-2)" "unprognostic (4.51e-2)" "unprognostic (1.68e-1)" 2.6 3.2 2.8 1.6 2.9 2.0 2.2 3.3 3.7 1.9 3.7 2.7 1.0 1.8 2.3 3.9 2.3 1.4 5.1 2.7 2.7 3.1 5.6 2.0 2.9 2.5 2.5 2.6 2.9 2.3 2.0 3.4 2.5 1.6 1.7 1.8 1.9 2.3 6.3 1.8 1.8 1.8 2.4 1.8 2.2 4.9 2.9 1.5 3.3 6.4 1.9 2.1 1.9 3.0 9.2 11.4 8.8 47.8 7.8 5.4 7.6 6.1 5.0 6.2 5.7 19.7 8.1 8.8 7.0 4.4 27.5 8.7 7.9 4.3 7.6 4.2 12.9 5.2 15.0 30.4 5.0 12.2 3.2 4.6 6.5 5.3 5.8 41.5 5.8 8.5 16.5 2.3 7.9 6.4 8.4 37.2 15.1 18.0 29.0 6.5 6.7 12.4 6.1 8.1 7.0 8.5 5.0 8.9 16.1 17.2 4.5 7.3 9.8 5.2 4.0 10.0 12.5 2.6 8.6 14.7 20.6 15.0 17.3 0.7 1.0 0.7 0.8 0.8 1.0 1.0 1.2 1.0 1.0 1.0 1.4 0.9 0.7 0.9 0.7 0.9 1.2 1.0 2.8 2.9 3.3 3.7 2.7 2.7 2.5 2.5 2.5 2.4 2.9 3.0 40.5 38.5 41.7 12.7 32.1 43.7 54.8 58.3 30.1 29.1 38.6 60.8 97.1 37.1 40.0 44.1 16.7 77.6 25.7 22.3 115.4 90.6 168.5 50.2 31.9 38.9 19.2 35.3 14.7 96.3 68.7 44.9 16.3 31.7 14.5 41.5 44.3 106.8 54.0 18.5 16.6 32.5 50.8 26.3 15.1 33.6 49.4 22.3 35.6 8.4 44.5 46.8 30.9 18.6 20.2 73.2 28.2 49.2 34.9 61.2 38.1 117.6 44.6 35.8 32.9 35.6 65.6 82.2 75.2 42.4 44.2 49.8 25.2 61.7 44.4 49.2 MAPK11 "p38-2, p38Beta, PRKM11, SAPK2" ENSG00000185386 "Mitogen-activated protein kinase 11" Q15759 22 50263713-50270767 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 70.9" "Cell type enhanced" "Detected in many" "Adipocytes: 29.5;Astrocytes: 16.6;Endothelial cells: 21.1;Excitatory neurons: 15.8;Hepatic stellate cells: 20.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012961, HPA045069" Approved Approved Mitochondria NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Mitochondria "CAB012961: AB_2533144, HPA045069: AB_2679207" "unprognostic (1.11e-1)" "unprognostic (1.28e-1)" "unprognostic (1.49e-2)" "unprognostic (1.92e-1)" "unprognostic (1.18e-2)" "unprognostic (1.64e-3)" "unprognostic (1.02e-1)" "unprognostic (5.84e-2)" "unprognostic (5.89e-2)" "unprognostic (2.46e-1)" "unprognostic (4.96e-3)" "unprognostic (2.18e-1)" "prognostic unfavorable (6.02e-6)" "unprognostic (9.84e-2)" "unprognostic (4.25e-2)" "unprognostic (9.16e-2)" "unprognostic (2.10e-2)" 27.5 6.8 52.3 7.9 56.0 1.1 24.0 48.2 70.9 15.1 40.6 7.3 1.9 15.5 5.8 9.4 16.7 8.7 18.9 55.2 49.6 18.6 4.8 16.8 9.4 48.2 47.2 12.5 5.7 5.4 28.4 8.3 48.2 18.2 2.6 8.6 7.2 7.2 6.4 7.5 8.3 9.4 47.4 16.3 10.9 6.1 50.2 3.5 11.0 5.8 6.1 11.6 12.3 51.0 2.8 6.8 7.4 27.8 9.5 14.3 0.2 10.2 7.4 6.8 2.7 2.8 5.2 0.0 8.7 9.9 11.3 6.9 4.9 4.2 0.5 13.9 3.4 10.1 10.4 0.6 10.9 2.5 15.0 19.9 12.3 1.9 0.8 7.7 15.2 10.6 8.1 26.8 6.9 12.4 0.5 9.4 0.6 8.4 7.7 26.7 0.1 9.9 10.3 0.0 6.8 18.4 9.0 3.7 7.7 0.9 12.2 7.9 24.0 20.4 16.5 1.5 3.7 1.2 3.2 11.8 10.4 2.9 17.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 52.3 56.0 48.2 70.9 55.2 49.6 48.2 47.2 48.2 47.4 50.2 51.0 29.5 0.0 1.1 16.6 2.2 1.9 1.8 3.2 8.0 3.3 1.1 1.5 6.6 1.5 1.7 0.0 6.2 0.0 1.8 0.1 1.9 1.0 4.7 0.6 1.8 21.1 0.0 0.4 15.8 0.2 0.4 2.7 0.5 1.7 0.0 0.1 20.0 2.1 0.3 0.0 3.6 0.2 2.0 1.3 2.1 9.7 3.1 0.5 5.4 13.1 0.1 5.9 0.0 1.0 0.9 0.7 0.0 2.2 1.6 2.9 0.0 1.9 1.3 11.4 0.0 0.6 1.8 1.3 3.2 1.8 1.3 0.0 3.3 0.7 0.1 1.1 MARCHF5 "FLJ20445, MARCH-V, MARCH5, MITOL, RNF153" ENSG00000198060 "Membrane associated ring-CH-type finger 5" Q9NX47 10 92291167-92353964 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 23.8;Cardiomyocytes: 28.6;Cytotrophoblasts: 39.2;Extravillous trophoblasts: 44.0;Hofbauer cells: 34.9;Syncytiotrophoblasts: 65.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056596 Supported Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Mitochondria "HPA056596: AB_2683181" "unprognostic (4.00e-2)" "unprognostic (5.15e-2)" "unprognostic (1.25e-1)" "unprognostic (4.10e-2)" "unprognostic (5.47e-3)" "unprognostic (2.33e-3)" "unprognostic (4.43e-1)" "unprognostic (1.63e-1)" "unprognostic (1.24e-2)" "unprognostic (9.77e-2)" "unprognostic (5.50e-3)" "unprognostic (4.02e-3)" "unprognostic (6.14e-2)" "unprognostic (2.87e-1)" "unprognostic (1.62e-1)" "unprognostic (4.53e-1)" "unprognostic (2.85e-2)" 13.6 14.0 9.1 7.7 9.6 17.3 15.0 9.1 11.9 12.2 10.4 9.8 11.3 13.3 12.6 19.3 10.1 10.7 12.8 9.6 9.4 15.1 20.1 10.4 9.0 9.0 9.4 14.0 9.2 12.5 7.0 7.8 8.8 15.1 10.1 8.8 13.7 7.8 18.2 9.8 11.6 10.7 9.6 8.9 10.5 8.8 9.3 12.5 17.2 16.1 9.8 10.7 12.2 9.7 28.0 14.8 28.7 33.1 19.2 19.8 14.8 24.5 26.7 29.8 30.4 10.0 19.6 16.2 16.5 24.1 13.0 22.4 20.3 20.5 42.5 12.3 23.9 13.1 13.6 23.7 23.2 21.1 12.4 20.4 27.0 19.7 40.9 39.6 26.6 17.0 14.5 19.7 24.2 17.7 18.7 24.1 6.7 18.1 22.1 20.0 29.4 9.8 30.8 17.8 13.3 24.5 21.3 15.5 26.7 13.7 27.1 16.1 26.0 13.9 15.3 15.3 34.0 19.9 16.2 14.2 12.7 28.7 9.5 4.2 6.0 7.0 5.1 7.5 5.2 5.2 5.7 5.5 6.9 4.5 5.7 5.5 12.2 5.0 6.7 4.6 5.9 5.0 9.1 9.6 9.1 11.9 9.6 9.4 9.0 9.4 8.8 9.6 9.3 9.7 23.8 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.6 0.0 0.0 0.0 0.0 39.2 12.9 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 44.0 9.3 0.0 0.0 0.0 0.0 0.0 0.0 34.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 65.3 2.8 0.0 0.0 0.0 MAVS "Cardif, IPS-1, KIAA1271, VISA" ENSG00000088888 "Mitochondrial antiviral signaling protein" Q7Z434 20 3846799-3876123 "Predicted membrane proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 100.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009187, HPA049850, HPA053524" Enhanced Enhanced Mitochondria NA NA 600000 "Cluster 14: Monocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "CAB009187: , HPA049850: AB_2680912, HPA053524: AB_2682177" "unprognostic (1.30e-2)" "unprognostic (4.51e-2)" "unprognostic (2.17e-1)" "unprognostic (6.67e-2)" "unprognostic (1.42e-1)" "unprognostic (1.75e-1)" "unprognostic (1.18e-3)" "unprognostic (2.23e-2)" "unprognostic (2.30e-2)" "unprognostic (5.95e-2)" "prognostic favorable (3.81e-4)" "unprognostic (1.92e-1)" "prognostic favorable (4.13e-5)" "unprognostic (4.97e-2)" "unprognostic (3.03e-1)" "unprognostic (3.12e-2)" "unprognostic (7.39e-2)" 14.2 12.5 13.0 11.5 16.0 10.3 13.0 13.9 13.6 11.6 14.1 19.4 14.8 12.0 8.4 14.9 13.2 6.7 21.3 12.1 11.5 15.8 15.5 13.3 9.9 18.6 15.7 16.8 17.6 15.4 12.1 9.4 15.9 14.2 15.4 8.1 13.0 10.3 37.5 18.9 16.9 9.6 14.0 14.3 15.4 4.9 16.1 10.4 14.0 29.2 10.8 14.3 11.0 16.6 31.6 36.0 14.3 17.9 38.8 26.2 11.2 18.7 23.8 19.5 14.2 28.4 19.9 13.6 11.1 26.4 55.6 38.7 17.3 28.0 19.9 8.4 8.4 26.3 14.6 45.5 21.4 16.6 10.6 26.7 23.4 33.2 19.6 19.4 20.1 17.6 30.2 10.1 19.3 28.5 25.3 14.1 9.2 15.7 19.6 18.8 19.9 13.7 20.8 31.2 10.7 11.2 21.3 41.0 18.1 20.3 21.9 15.3 30.5 26.5 9.7 31.7 22.1 20.7 26.6 9.4 10.5 20.1 13.7 1.7 2.1 2.0 1.4 1.6 1.0 1.1 1.1 1.1 1.4 1.3 1.2 1.2 1.9 1.8 1.9 1.7 0.9 1.6 13.0 16.0 13.9 13.6 12.1 11.5 18.6 15.7 15.9 14.0 16.1 16.6 16.6 57.7 48.5 24.8 17.3 2.2 13.9 3.7 19.4 34.0 19.9 13.2 61.0 58.6 21.7 29.5 16.7 33.6 22.5 100.0 13.7 25.9 1.1 16.1 27.5 26.8 34.7 17.1 13.6 30.5 27.5 22.8 25.0 16.6 8.8 36.5 44.3 45.7 25.5 45.4 15.9 32.6 2.0 37.7 2.9 3.2 30.7 20.7 1.8 15.9 32.4 20.7 20.6 12.5 19.9 32.7 29.5 28.2 14.2 18.1 42.8 19.6 16.2 33.7 32.9 26.2 17.5 6.2 4.1 15.6 2.0 18.1 16.7 27.5 57.9 16.6 MCAT "fabD, FASN2C, MCT, MCT1, MT, NET62" ENSG00000100294 "Malonyl-CoA-acyl carrier protein transacylase" Q8IVS2 22 43132209-43143398 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 94.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003122, HPA035471" Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA003122: AB_2666795, HPA035471: AB_10670590" "unprognostic (1.05e-1)" "unprognostic (1.57e-2)" "unprognostic (1.39e-2)" "prognostic favorable (5.53e-4)" "unprognostic (3.52e-1)" "unprognostic (1.34e-1)" "unprognostic (1.36e-3)" "unprognostic (4.71e-2)" "unprognostic (5.13e-2)" "unprognostic (2.94e-1)" "unprognostic (1.32e-1)" "unprognostic (9.86e-2)" "prognostic favorable (2.18e-4)" "prognostic favorable (3.89e-4)" "unprognostic (3.67e-2)" "unprognostic (1.76e-1)" "unprognostic (3.08e-1)" 10.2 21.6 11.8 5.7 12.5 9.0 11.7 11.1 14.4 9.2 17.1 12.5 6.7 11.5 9.9 15.5 14.3 6.6 18.2 13.6 12.5 25.1 22.7 8.7 5.1 11.9 11.6 11.3 15.0 17.6 16.6 4.6 12.2 13.5 7.1 7.2 13.3 6.6 21.9 14.9 8.6 5.8 10.6 8.1 14.8 17.1 12.0 7.8 13.1 10.1 6.1 10.8 10.3 11.0 14.1 18.2 12.6 22.3 10.4 11.0 12.9 15.4 13.6 20.3 18.8 18.3 14.1 23.6 15.5 11.5 11.5 23.3 24.1 20.4 15.1 8.2 71.3 8.8 21.6 20.6 16.6 42.3 10.3 8.3 19.5 19.9 15.7 11.8 14.7 14.1 21.1 9.4 10.1 26.0 19.9 46.0 12.3 19.8 31.8 26.0 12.4 37.7 25.7 12.1 16.6 8.8 16.6 32.0 24.3 5.7 16.5 27.1 8.9 8.8 17.4 19.2 22.0 16.6 18.4 17.1 19.0 16.0 10.8 0.0 11.4 0.8 8.8 11.1 11.5 9.4 9.7 11.4 16.4 12.4 10.9 7.9 2.9 14.5 6.9 16.2 7.0 7.3 11.8 12.5 11.1 14.4 13.6 12.5 11.9 11.6 12.2 10.6 12.0 11.0 8.0 6.4 6.8 3.9 6.9 17.8 12.3 19.6 5.7 11.2 13.6 11.4 9.5 31.5 10.6 20.2 0.0 18.7 5.7 12.3 50.9 32.0 23.4 28.5 8.3 9.4 14.5 17.9 3.6 21.8 11.9 8.8 12.2 9.2 3.8 10.8 17.5 22.3 15.5 6.7 3.7 14.7 14.2 6.3 4.3 11.8 7.5 6.1 7.2 0.0 8.2 12.5 4.1 1.5 2.1 23.7 15.2 16.6 5.6 17.3 12.5 94.3 27.7 9.6 19.7 11.2 10.0 30.0 11.7 9.0 21.0 9.2 4.8 30.5 22.4 11.5 MCCC1 MCCA ENSG00000078070 "Methylcrotonoyl-CoA carboxylase 1" Q96RQ3 3 183015218-183116075 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "T-47d: 153.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008310 Approved Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA008310: AB_1853620" "unprognostic (4.01e-2)" "unprognostic (1.83e-3)" "unprognostic (2.05e-2)" "unprognostic (2.59e-3)" "unprognostic (3.46e-2)" "unprognostic (4.16e-2)" "unprognostic (1.69e-1)" "unprognostic (1.10e-3)" "unprognostic (2.57e-3)" "unprognostic (9.82e-2)" "unprognostic (9.74e-2)" "unprognostic (7.65e-2)" "prognostic favorable (3.68e-4)" "unprognostic (4.73e-1)" "unprognostic (2.21e-1)" "unprognostic (2.95e-1)" "unprognostic (1.36e-1)" 37.9 22.6 9.5 9.5 10.9 13.9 33.2 9.9 13.4 12.3 13.8 17.4 16.1 10.1 14.6 17.6 12.2 11.9 34.2 9.2 9.3 58.8 59.3 17.9 11.7 9.5 9.1 17.2 31.2 18.7 8.4 6.3 10.6 15.1 18.6 10.8 18.0 13.4 21.9 12.2 13.8 10.6 9.3 11.8 21.7 9.1 11.1 16.0 18.9 26.3 15.5 26.5 9.4 13.3 43.1 16.5 10.3 10.6 42.6 19.1 20.4 19.5 26.4 21.1 23.5 22.9 17.1 47.6 31.0 17.2 35.8 22.0 15.4 12.9 26.4 16.6 17.0 40.0 18.3 23.9 28.7 27.5 22.0 21.6 14.5 10.0 23.3 14.0 28.6 40.7 22.7 24.7 23.6 35.4 27.1 15.9 11.2 66.3 17.9 22.4 22.6 60.1 32.2 67.2 22.0 16.4 75.3 100.1 21.1 10.7 153.9 37.8 14.0 15.8 12.5 12.8 28.6 24.3 48.8 48.2 16.8 38.4 15.2 14.4 13.3 25.0 10.7 15.6 12.3 17.9 14.1 11.8 26.6 15.4 14.7 13.1 2.1 25.4 16.8 17.3 9.6 10.7 9.5 10.9 9.9 13.4 9.2 9.3 9.5 9.1 10.6 9.3 11.1 13.3 6.2 9.6 53.9 44.7 14.6 7.0 20.1 17.9 15.9 13.0 10.6 9.5 32.8 31.5 20.2 27.6 10.4 35.4 6.3 7.2 33.2 25.3 5.4 11.0 10.2 6.6 6.0 10.9 66.6 17.2 5.4 10.3 21.4 21.9 7.6 19.0 6.1 36.5 16.5 8.4 56.9 13.6 16.2 11.1 8.6 5.5 8.7 10.5 7.2 44.0 10.5 12.0 4.1 47.7 61.6 13.4 15.8 10.5 12.5 10.4 13.5 40.6 21.4 11.2 6.6 11.6 9.6 8.1 4.4 22.3 5.8 28.3 10.1 24.3 20.5 21.7 MCCC2 MCCB ENSG00000131844 "Methylcrotonoyl-CoA carboxylase 2" Q9HCC0 5 71587288-71658706 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 120.5" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 107.0" "Cancer enhanced" "Detected in all" "prostate cancer: 81.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038300, HPA038301, HPA061546" Enhanced Enhanced Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 44: Endometrium - Transcription" Mitochondria "HPA038300: AB_2675941, HPA038301: AB_10670661, HPA061546: AB_2684557" "unprognostic (2.39e-1)" "unprognostic (6.89e-3)" "prognostic favorable (3.62e-4)" "unprognostic (1.79e-2)" "unprognostic (1.89e-2)" "unprognostic (8.07e-2)" "prognostic favorable (1.70e-4)" "unprognostic (1.01e-1)" "unprognostic (3.37e-1)" "unprognostic (5.39e-2)" "unprognostic (2.90e-1)" "unprognostic (2.38e-1)" "prognostic favorable (6.43e-8)" "unprognostic (1.27e-1)" "unprognostic (1.29e-1)" "unprognostic (5.15e-2)" "unprognostic (3.47e-2)" 21.3 47.6 13.4 13.5 13.7 6.0 60.0 12.4 15.5 21.3 24.9 30.5 27.2 14.4 38.9 25.4 17.2 15.2 54.9 12.0 13.1 73.3 120.5 13.4 17.8 14.8 13.4 14.2 24.6 32.8 14.1 14.2 14.8 48.2 35.9 12.2 28.2 20.6 34.4 19.8 20.7 11.7 16.3 15.6 25.8 8.6 16.0 14.2 44.6 35.4 21.5 27.0 15.0 18.4 38.5 52.4 21.4 82.5 22.4 23.0 36.9 16.4 29.4 35.7 25.7 91.1 46.9 90.4 62.8 25.9 28.0 30.8 37.8 58.8 44.3 47.6 45.6 48.2 24.7 100.5 39.2 24.4 42.8 29.5 30.1 32.6 25.8 15.8 31.7 24.9 63.2 31.6 24.9 103.0 0.3 42.9 29.0 33.2 27.2 46.3 64.5 130.9 92.5 66.9 32.9 36.7 80.1 111.8 38.8 10.1 92.7 59.6 22.7 14.4 22.1 26.1 49.9 22.4 46.2 54.6 23.7 66.3 36.6 2.0 8.4 1.9 6.5 13.5 8.5 9.7 8.4 7.4 19.4 9.9 8.3 9.1 1.3 14.7 8.1 8.1 12.1 8.3 13.4 13.7 12.4 15.5 12.0 13.1 14.8 13.4 14.8 16.3 16.0 18.4 9.1 16.0 23.6 27.4 26.8 13.3 17.5 20.2 22.2 12.6 54.9 28.3 61.5 20.0 22.3 16.5 6.2 48.5 17.6 26.3 21.5 20.6 4.3 94.0 24.0 15.1 29.5 13.9 22.2 18.2 23.0 13.1 30.1 107.0 12.7 22.7 9.7 93.1 18.0 3.3 21.6 22.8 8.2 12.1 11.2 9.8 13.7 14.0 12.4 11.2 17.9 15.4 20.6 30.2 28.0 15.3 17.0 20.3 27.2 29.6 23.6 59.1 17.7 10.8 6.6 15.2 9.0 4.2 12.0 35.9 13.8 63.6 17.9 30.9 33.9 20.9 MCL1 "BCL2L3, Mcl-1" ENSG00000143384 "MCL1 apoptosis regulator, BCL2 family member" Q07820 1 150560895-150579738 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Differentiation" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 685.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 106.3" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 12 "U-698: 4726.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002781, HPA008455, HPA031125, CAB068195" Enhanced Enhanced Mitochondria Yes No "Cluster 52: Eosinophils - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Mitochondria "CAB002781: , CAB068195: AB_2665695, HPA008455: AB_1079334, HPA031125: AB_10602026" "unprognostic (3.82e-2)" "unprognostic (8.79e-2)" "unprognostic (9.15e-2)" "unprognostic (2.05e-2)" "unprognostic (1.34e-1)" "unprognostic (3.91e-2)" "unprognostic (3.16e-2)" "unprognostic (2.43e-2)" "unprognostic (1.29e-1)" "unprognostic (8.60e-2)" "unprognostic (1.57e-2)" "unprognostic (1.65e-2)" "prognostic unfavorable (7.16e-4)" "unprognostic (3.22e-2)" "unprognostic (1.94e-1)" "unprognostic (4.87e-2)" "unprognostic (4.46e-2)" 297.8 149.2 72.9 264.9 75.0 685.1 175.0 77.0 84.2 143.4 85.0 137.1 99.4 98.5 41.8 199.3 190.7 278.8 139.1 65.3 81.5 125.2 404.6 237.1 161.2 86.4 77.8 105.3 161.7 89.2 82.8 146.9 79.4 96.3 120.1 90.1 124.7 56.4 153.8 189.2 133.6 171.4 80.6 171.5 167.0 41.3 91.4 128.9 133.3 160.1 157.1 302.6 124.6 75.8 140.2 74.8 131.9 73.3 262.9 262.2 175.8 164.8 174.5 173.0 139.4 91.9 112.3 184.9 102.2 120.2 80.3 187.7 101.7 203.3 166.7 154.8 68.3 76.4 109.9 106.2 204.7 130.6 151.3 147.3 221.3 170.6 330.0 159.5 192.7 49.4 168.1 225.3 234.2 160.3 64.6 80.7 242.0 122.9 131.9 94.7 111.1 85.9 195.2 103.7 95.9 134.2 125.6 135.9 232.4 191.2 100.4 195.2 251.6 109.2 119.4 55.5 212.8 310.2 409.5 4726.7 189.5 95.1 141.9 23.3 19.8 51.8 15.0 17.4 17.4 12.6 19.0 16.6 16.6 14.0 22.8 17.6 106.3 10.6 16.2 9.4 30.1 11.2 72.9 75.0 77.0 84.2 65.3 81.5 86.4 77.8 79.4 80.6 91.4 75.8 366.0 198.7 295.5 12.4 339.2 489.2 394.7 142.6 434.2 38.7 339.3 229.9 84.8 228.8 148.8 33.1 60.5 108.6 398.5 491.8 41.1 196.4 209.2 187.5 310.8 241.9 259.6 61.8 6.5 174.7 203.4 278.4 228.3 365.7 343.8 209.0 229.2 218.8 262.7 11.8 5.5 309.0 107.8 453.6 930.9 347.0 72.7 614.2 273.9 30.0 250.6 101.2 94.7 10.1 6.8 183.4 345.1 60.9 831.8 293.4 233.1 68.9 110.3 78.0 78.9 350.3 217.4 47.4 35.4 372.2 572.0 270.4 499.8 126.0 205.7 401.1 MCU "C10orf42, CCDC109A, FLJ46135" ENSG00000156026 "Mitochondrial calcium uniporter" Q8NE86 10 72692131-72887694 "Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 53.7" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 68.3;Inhibitory neurons: 65.6;Oligodendrocyte precursor cells: 72.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016480 Approved Supported Mitochondria No No 17000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA016480: AB_2071893" "unprognostic (2.42e-2)" "unprognostic (1.58e-2)" "unprognostic (3.01e-2)" "unprognostic (5.37e-2)" "unprognostic (7.84e-2)" "unprognostic (3.05e-1)" "prognostic unfavorable (6.06e-5)" "unprognostic (1.23e-1)" "unprognostic (2.28e-1)" "unprognostic (2.33e-1)" "unprognostic (5.12e-3)" "unprognostic (1.73e-1)" "prognostic favorable (5.07e-4)" "unprognostic (4.51e-2)" "unprognostic (3.79e-1)" "unprognostic (2.74e-2)" "unprognostic (2.48e-2)" 6.1 3.8 2.8 7.4 2.5 19.9 5.7 10.4 3.6 8.3 6.4 28.7 27.8 8.9 3.0 14.2 10.8 12.7 7.8 3.9 2.8 10.6 7.0 10.2 4.9 3.4 3.2 4.9 5.5 10.0 1.9 12.8 3.2 5.8 30.8 2.3 6.7 5.7 41.8 6.8 24.5 13.5 3.0 5.0 43.2 4.3 3.3 5.7 6.4 53.7 7.7 14.9 5.1 2.8 41.7 66.1 16.8 12.2 25.0 28.0 17.1 25.0 35.5 24.5 26.0 39.6 38.6 17.7 19.6 30.8 13.3 36.9 22.2 29.8 32.5 19.5 20.8 22.1 23.5 22.1 19.5 56.0 17.9 28.7 24.9 22.0 46.6 38.4 29.8 18.5 14.0 12.9 23.0 24.3 15.2 12.0 18.5 45.2 13.6 15.7 35.8 4.7 32.7 22.4 17.8 7.9 30.8 34.1 7.5 20.2 6.8 14.5 24.3 11.8 19.9 25.7 16.9 9.4 12.8 12.1 15.8 27.5 9.2 1.8 6.7 18.6 3.0 7.3 3.1 3.5 2.9 3.6 5.8 1.7 2.3 2.6 8.8 2.2 8.9 2.0 5.2 4.2 2.8 2.5 10.4 3.6 3.9 2.8 3.4 3.2 3.2 3.0 3.3 2.8 13.7 35.3 17.0 21.2 4.2 11.7 14.4 8.9 10.8 3.0 5.9 3.9 6.6 8.6 22.0 18.4 2.1 7.3 4.8 38.2 1.9 11.1 14.5 23.3 9.9 9.7 8.4 10.8 58.2 25.2 10.1 7.2 68.3 26.4 8.2 3.4 8.9 5.8 6.7 0.0 65.6 28.2 12.2 6.0 2.9 7.2 5.3 6.7 8.8 37.5 5.7 5.4 2.1 72.4 40.3 40.7 15.6 4.1 5.7 9.7 19.8 8.6 22.6 3.9 13.1 6.8 12.1 5.1 5.2 6.2 12.4 9.3 5.0 12.7 24.5 26.8 MDH2 ENSG00000146701 "Malate dehydrogenase 2" P40926 7 76048051-76067508 "Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" Oxidoreductase "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 697.1;tongue: 601.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019714, HPA019716, HPA019848, HPA026720" Enhanced Enhanced Mitochondria No No 14000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA019714: AB_1853678, HPA019716: AB_1853680, HPA019848: AB_1853683, HPA026720: AB_1853685" "unprognostic (3.20e-2)" "unprognostic (2.85e-1)" "unprognostic (1.11e-1)" "unprognostic (1.43e-2)" "unprognostic (5.55e-3)" "unprognostic (8.94e-2)" "unprognostic (6.45e-2)" "unprognostic (3.77e-2)" "unprognostic (3.60e-1)" "unprognostic (2.02e-2)" "unprognostic (1.40e-1)" "unprognostic (9.70e-2)" "prognostic favorable (1.49e-5)" "unprognostic (8.57e-2)" "unprognostic (9.64e-2)" "unprognostic (5.68e-2)" "unprognostic (2.66e-1)" 76.9 163.4 68.0 51.4 73.6 71.9 73.9 62.1 83.9 67.4 81.3 118.7 112.7 69.2 34.7 144.9 66.8 38.0 367.5 73.5 69.9 121.7 215.5 60.7 62.4 66.7 61.4 64.1 118.3 90.5 70.7 45.2 67.0 67.3 80.3 40.2 98.8 56.8 697.1 119.5 94.4 60.0 56.3 75.6 103.2 60.2 64.1 60.4 62.3 601.9 66.2 85.6 82.4 66.6 176.5 278.4 99.2 250.7 110.3 121.2 172.0 113.9 145.8 159.4 143.2 246.2 204.7 261.3 51.1 151.1 172.6 174.4 256.3 170.0 112.7 192.1 368.3 144.6 138.7 229.9 135.2 229.3 144.6 153.7 149.7 155.2 229.3 124.9 150.9 160.5 466.3 149.4 149.7 389.6 206.4 402.1 222.8 306.6 344.3 164.3 121.7 379.9 149.9 225.5 247.4 226.9 114.6 567.5 247.0 124.9 323.4 260.0 117.7 160.0 151.6 175.5 232.7 166.5 148.1 290.8 138.6 289.1 249.1 95.4 129.9 63.3 102.4 148.8 107.1 122.2 113.7 111.2 176.0 110.2 109.0 102.6 34.0 107.4 164.2 157.2 156.6 175.8 68.0 73.6 62.1 83.9 73.5 69.9 66.7 61.4 67.0 56.3 64.1 66.6 98.8 51.3 65.9 7.8 110.2 135.9 190.8 437.9 118.4 68.0 151.8 165.5 486.2 135.8 217.3 115.8 18.8 328.1 104.9 242.3 448.0 269.8 263.7 108.0 97.9 96.8 169.7 97.2 13.0 333.1 334.0 112.6 111.1 104.8 54.5 150.9 88.5 246.6 248.1 72.3 15.0 280.6 288.9 132.6 113.5 161.5 99.4 117.6 181.5 9.4 171.4 85.7 126.7 8.0 12.8 255.0 252.1 99.3 149.8 197.3 433.3 466.3 139.0 67.3 85.5 114.7 150.9 157.8 65.3 256.6 166.1 294.8 105.4 233.4 372.7 234.7 ME2 ENSG00000082212 "Malic enzyme 2" P23368 18 50879080-50954257 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Allosteric enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 176.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008247, HPA008880" Enhanced Supported Mitochondria NA NA 84000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "HPA008247: AB_1853704, HPA008880: AB_1853702" "unprognostic (1.23e-1)" "unprognostic (3.26e-1)" "unprognostic (9.57e-3)" "unprognostic (2.22e-1)" "unprognostic (4.97e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (8.29e-8)" "unprognostic (1.97e-1)" "unprognostic (3.66e-2)" "unprognostic (1.02e-1)" "unprognostic (1.34e-2)" "unprognostic (4.75e-2)" "unprognostic (1.43e-2)" "unprognostic (4.27e-3)" "unprognostic (2.30e-1)" "unprognostic (2.47e-1)" "unprognostic (4.09e-1)" 12.1 15.7 12.7 21.9 13.6 15.6 9.3 14.1 16.8 8.9 55.5 30.6 38.3 9.0 8.9 12.8 8.5 12.7 45.0 14.8 15.4 12.6 15.1 11.6 25.8 15.6 16.2 8.0 20.9 32.2 10.0 13.1 16.2 13.8 32.4 14.6 7.2 19.9 26.2 8.8 32.3 18.1 13.9 27.2 26.5 18.8 15.4 21.4 10.9 22.9 22.6 16.8 3.4 14.3 40.5 39.9 52.0 61.0 23.2 25.6 24.2 33.2 24.7 42.2 35.5 18.4 21.8 143.3 12.8 29.7 38.5 32.6 78.1 33.3 48.2 60.0 11.6 36.5 22.8 21.5 68.1 123.9 42.5 16.0 40.3 53.1 85.8 27.8 55.0 83.5 39.9 34.1 29.1 8.4 90.4 12.3 34.8 29.0 15.9 58.0 25.8 41.1 45.9 8.6 63.9 34.0 31.0 18.7 33.0 31.0 14.4 59.0 34.6 30.0 32.7 15.8 44.7 62.9 27.1 70.6 30.2 86.5 32.5 7.5 16.4 20.7 6.5 19.0 5.1 7.1 4.2 7.9 13.3 7.2 3.6 4.5 18.1 9.8 25.7 4.4 4.4 7.4 12.7 13.6 14.1 16.8 14.8 15.4 15.6 16.2 16.2 13.9 15.4 14.3 20.9 9.6 11.9 40.1 32.8 15.2 20.2 13.6 12.5 17.0 10.9 10.0 103.6 11.5 22.6 14.7 14.6 16.7 37.9 39.0 39.2 31.9 18.0 18.5 22.6 18.7 12.0 16.6 35.6 38.6 16.3 19.1 43.3 19.1 16.4 176.4 24.3 9.1 89.7 8.4 45.9 27.3 18.3 93.8 15.1 6.7 11.5 54.5 12.4 47.8 48.3 18.0 48.4 52.3 32.5 35.6 22.3 16.6 61.5 25.0 72.4 17.1 10.6 55.0 6.6 23.0 23.2 59.8 30.6 13.2 10.7 8.6 28.1 22.4 36.5 17.4 MECR "CGI-63, ETR1, FASN2B, NRBF1" ENSG00000116353 "Mitochondrial trans-2-enoyl-CoA reductase" Q9BV79 1 29192657-29230942 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 42.1" "Cell type enhanced" "Detected in all" "Late spermatids: 82.5;Rod photoreceptor cells: 68.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022018, HPA022030, HPA028740" Enhanced Supported Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 25: RPMI-8226 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" Mitochondria "HPA022018: AB_1853714, HPA022030: AB_1853716, HPA028740: AB_10601133" "unprognostic (2.53e-1)" "unprognostic (1.09e-2)" "unprognostic (1.52e-1)" "unprognostic (1.84e-1)" "unprognostic (1.07e-1)" "unprognostic (2.46e-1)" "unprognostic (1.39e-1)" "unprognostic (2.07e-1)" "unprognostic (1.34e-1)" "unprognostic (1.69e-1)" "unprognostic (3.06e-2)" "unprognostic (8.66e-2)" "prognostic favorable (5.81e-6)" "unprognostic (7.01e-3)" "unprognostic (3.29e-2)" "unprognostic (2.59e-1)" "prognostic unfavorable (5.29e-4)" 14.7 14.6 5.1 1.7 5.1 1.8 13.4 3.3 6.2 10.2 3.1 10.3 1.4 12.9 2.5 12.5 9.4 1.3 24.8 6.0 3.9 14.1 15.8 7.3 2.0 5.2 4.0 10.0 8.9 4.5 7.2 3.5 5.4 7.9 2.6 9.9 12.3 3.0 42.1 15.4 7.2 3.1 3.2 6.7 11.1 7.6 4.3 1.4 8.3 5.8 2.1 9.6 9.6 5.2 3.9 4.5 3.2 4.6 2.9 2.5 6.8 3.7 3.8 4.7 3.9 2.3 5.6 7.3 5.1 3.7 1.3 3.0 5.4 6.3 4.0 4.4 6.9 6.4 3.4 4.1 6.6 6.1 1.9 4.3 5.9 3.1 11.0 3.8 3.5 6.9 5.8 4.2 4.7 4.5 3.9 2.9 6.5 5.8 4.3 3.5 4.2 9.3 5.9 2.4 5.1 4.5 4.1 4.7 7.0 4.4 2.3 5.4 3.8 2.4 2.9 4.1 4.7 2.7 2.2 5.0 3.9 8.4 5.2 0.1 2.2 0.0 1.5 2.1 4.1 2.2 1.6 1.7 1.9 1.1 2.3 1.6 0.3 2.9 1.6 2.5 2.4 1.2 5.1 5.1 3.3 6.2 6.0 3.9 5.2 4.0 5.4 3.2 4.3 5.2 8.8 12.8 3.9 14.7 9.1 5.6 15.6 26.9 7.4 12.8 12.0 14.6 19.8 21.5 21.4 20.2 10.4 46.0 3.8 7.4 41.1 24.3 40.8 19.7 13.6 9.1 7.8 10.1 25.1 19.7 42.4 12.8 4.6 12.8 5.7 17.5 7.1 19.7 20.8 8.4 20.3 9.4 12.2 6.0 5.1 82.5 13.7 5.3 16.0 3.7 10.8 14.5 10.3 11.6 15.2 16.3 8.0 10.9 10.3 20.6 10.9 46.0 11.3 68.5 13.1 13.2 12.9 8.5 16.1 14.0 7.4 27.9 6.0 25.8 18.3 20.5 METTL4 "FLJ23017, HsT661" ENSG00000101574 "Methyltransferase like 4" Q8N3J2 18 2537525-2571509 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Chromatin regulator, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040061, HPA046734" Approved Approved Mitochondria NA Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 16: Immune cells - Immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA040061: AB_10697713, HPA046734: AB_2732532" "unprognostic (1.85e-2)" "unprognostic (1.27e-1)" "unprognostic (7.31e-2)" "unprognostic (1.07e-1)" "unprognostic (1.11e-1)" "unprognostic (5.06e-3)" "unprognostic (1.12e-5)" "unprognostic (1.74e-1)" "unprognostic (5.12e-2)" "unprognostic (2.23e-2)" "unprognostic (2.24e-1)" "unprognostic (1.89e-1)" "unprognostic (7.72e-2)" "unprognostic (3.26e-1)" "unprognostic (4.00e-1)" "unprognostic (2.96e-2)" "unprognostic (1.05e-3)" 7.4 4.9 5.2 7.9 6.0 5.5 5.8 5.7 7.0 8.4 5.6 5.9 5.7 7.5 5.4 6.1 6.2 5.7 5.6 4.9 5.7 6.4 5.0 6.2 11.5 6.3 5.6 6.8 4.4 6.4 5.2 5.9 6.5 6.6 6.7 5.1 5.5 7.1 3.4 5.9 7.9 6.7 6.1 10.4 5.8 7.3 5.6 10.4 8.9 5.5 11.0 6.8 7.8 7.6 12.7 5.0 15.1 8.3 5.9 8.7 19.0 19.9 15.7 18.2 16.9 10.8 9.2 24.3 11.5 8.3 16.4 10.7 24.7 9.3 21.2 18.6 9.1 10.6 10.5 7.9 9.0 23.1 12.0 7.1 19.3 19.6 12.0 10.3 17.8 15.9 14.0 33.8 14.3 5.7 16.0 7.4 9.2 10.5 8.2 12.5 13.6 16.7 8.9 7.0 27.6 12.8 16.2 9.3 18.6 11.6 10.8 14.8 11.1 21.9 28.9 19.4 26.3 16.1 47.6 15.7 14.1 15.5 23.8 18.6 2.7 7.3 6.1 2.6 7.0 6.2 7.0 8.5 1.9 7.3 8.5 7.9 10.0 5.9 2.2 3.8 8.8 4.9 5.2 6.0 5.7 7.0 4.9 5.7 6.3 5.6 6.5 6.1 5.6 7.6 24.3 12.8 8.2 8.5 21.1 4.8 13.6 6.5 10.8 9.6 7.6 7.4 3.8 10.0 10.3 3.7 14.6 7.5 13.7 10.1 0.0 5.9 6.9 7.5 9.1 10.0 2.4 11.0 17.0 7.3 9.4 7.3 12.2 7.4 7.0 10.3 11.4 4.9 6.0 8.4 20.3 7.6 4.1 7.0 6.5 3.3 12.8 7.0 3.6 14.0 4.5 6.6 13.4 18.1 25.8 8.3 4.0 10.9 15.0 10.8 10.1 5.1 12.0 6.5 13.1 8.3 6.8 30.5 21.8 9.0 4.8 10.4 18.3 8.5 6.2 19.4 MFF "C2orf33, GL004" ENSG00000168958 "Mitochondrial fission factor" Q9GZY8 2 227325151-227357836 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 985.9;Late spermatids: 1746.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010968, HPA074625" Enhanced Supported Mitochondria No No 62000 "Cluster 2: Granulocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 20: HeLa - Mitochondria" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "HPA010968: AB_1845714, HPA074625: AB_2686704" "unprognostic (2.75e-2)" "unprognostic (1.35e-1)" "unprognostic (2.16e-1)" "unprognostic (1.15e-2)" "unprognostic (1.73e-2)" "unprognostic (1.46e-1)" "prognostic unfavorable (1.20e-4)" "unprognostic (3.07e-2)" "unprognostic (1.32e-1)" "unprognostic (6.07e-2)" "unprognostic (3.00e-2)" "unprognostic (6.24e-3)" "unprognostic (5.50e-2)" "unprognostic (1.00e-1)" "unprognostic (2.70e-2)" "unprognostic (1.51e-1)" "unprognostic (3.22e-1)" 52.3 58.0 61.2 29.3 66.6 48.1 46.9 67.4 71.8 49.0 63.5 60.9 41.0 46.6 37.9 48.4 49.0 31.0 66.2 60.0 67.3 68.8 44.2 38.9 39.4 66.4 61.7 51.6 57.2 60.0 42.7 33.4 66.1 42.5 40.9 80.4 43.8 47.9 100.4 44.8 40.5 42.3 67.3 38.7 49.0 199.2 63.5 51.5 37.1 86.5 44.5 50.1 45.9 74.5 71.1 60.6 72.4 100.5 92.7 88.6 95.3 69.1 93.7 82.6 88.7 66.4 49.8 40.3 80.1 76.9 87.5 57.8 121.0 88.5 112.6 86.4 97.3 85.8 144.5 165.0 122.4 84.2 73.6 79.6 113.9 79.0 84.3 109.6 72.7 91.6 76.7 117.8 75.3 72.5 88.9 127.3 98.6 76.7 62.5 79.0 91.8 78.7 124.2 66.5 76.3 70.8 153.3 68.7 106.7 59.4 44.8 82.0 49.7 80.6 67.0 119.2 78.3 95.2 69.6 81.9 106.1 73.6 111.7 118.5 66.8 133.6 65.2 74.0 69.9 84.0 67.5 63.9 72.0 77.9 70.4 60.2 65.1 67.7 70.0 71.9 97.5 76.3 61.2 66.6 67.4 71.8 60.0 67.3 66.4 61.7 66.1 67.3 63.5 74.5 40.4 32.1 46.7 53.8 74.8 48.3 62.1 70.3 90.5 33.1 54.9 64.1 79.3 44.3 57.0 60.7 31.3 95.3 49.8 46.2 127.2 95.2 985.9 36.7 40.3 45.6 32.3 73.6 95.8 94.8 89.8 67.6 42.8 52.0 22.1 66.4 43.5 56.1 78.4 40.4 97.7 60.3 61.1 61.5 56.4 1746.9 88.0 63.0 81.8 47.8 64.0 204.4 74.2 135.2 151.3 91.7 63.8 85.7 127.7 66.5 69.5 135.7 32.3 65.5 59.2 69.1 62.1 392.3 96.9 87.6 47.3 91.9 57.2 63.7 73.0 71.6 MFN1 FLJ20693 ENSG00000171109 "Mitofusin 1" Q8IWA4 3 179347709-179394936 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 92.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033437, HPA059230" Approved Supported Mitochondria NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 44: Endometrium - Transcription" Mitochondria "CAB033437: AB_2250540, HPA059230: AB_2683952" "unprognostic (2.94e-2)" "unprognostic (5.56e-2)" "unprognostic (5.44e-3)" "prognostic unfavorable (6.70e-4)" "prognostic favorable (6.11e-4)" "unprognostic (1.23e-1)" "prognostic unfavorable (8.08e-5)" "unprognostic (6.37e-2)" "unprognostic (1.86e-2)" "unprognostic (3.70e-2)" "unprognostic (3.76e-3)" "unprognostic (7.91e-2)" "unprognostic (7.90e-2)" "unprognostic (1.58e-1)" "unprognostic (3.83e-1)" "unprognostic (6.24e-2)" "unprognostic (9.79e-2)" 9.5 9.0 5.6 9.4 6.6 8.4 11.0 8.8 8.5 9.5 8.8 12.5 8.9 11.4 14.9 14.1 10.2 9.6 23.4 5.6 5.5 10.4 8.8 8.8 12.8 6.3 5.8 9.1 17.9 13.3 6.7 7.9 6.0 12.4 10.5 10.3 14.1 9.6 14.0 14.5 9.8 11.4 5.2 9.9 10.8 9.0 5.7 8.6 10.4 16.4 11.9 12.7 8.9 9.5 32.2 9.4 17.9 29.1 25.1 23.2 23.6 19.6 20.2 20.2 23.9 23.5 13.0 10.8 20.0 29.1 40.9 18.5 25.4 19.4 35.3 17.2 19.5 17.8 19.4 13.1 20.5 9.5 16.3 16.2 16.7 21.9 15.4 16.8 26.0 17.9 13.2 14.1 28.6 17.1 14.0 7.1 21.3 32.1 17.3 9.7 28.1 40.4 19.1 33.4 16.8 23.9 18.3 48.5 26.6 18.2 66.6 6.8 22.0 17.6 19.4 27.6 29.0 18.6 21.9 18.0 19.7 15.8 19.5 4.2 2.5 5.8 2.6 3.1 4.5 5.1 3.0 2.7 2.3 6.2 2.7 3.2 5.8 2.9 2.4 2.8 2.9 1.4 5.6 6.6 8.8 8.5 5.6 5.5 6.3 5.8 6.0 5.2 5.7 9.5 21.3 25.6 36.8 39.8 27.3 16.7 12.3 12.6 20.5 18.8 19.1 14.4 29.3 14.3 23.7 18.4 39.6 11.2 20.9 18.2 9.8 12.6 6.6 36.9 28.5 16.3 10.2 24.0 77.2 17.4 11.0 22.6 26.0 43.4 8.8 22.1 14.6 18.3 7.8 11.8 92.5 18.2 12.2 11.7 11.4 3.3 13.4 14.9 12.4 28.1 12.2 11.2 18.6 56.8 85.1 16.5 11.8 17.7 21.2 20.0 10.4 13.4 31.9 16.5 6.6 26.8 21.2 33.2 13.7 24.9 27.0 13.1 15.1 25.3 16.6 20.7 MFN2 "CMT2A2, CPRP1, KIAA0214, MARF" ENSG00000116688 "Mitofusin 2" O95140 1 11980181-12015211 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy, Unfolded protein response" Hydrolase "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 270.4;skeletal muscle: 310.5;tongue: 337.6" "Cell type enriched" "Detected in all" 7 "Cardiomyocytes: 336.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030554, CAB079902" Uncertain Supported Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "CAB079902: AB_2724683, HPA030554: AB_10603018" "unprognostic (9.52e-2)" "unprognostic (1.80e-1)" "unprognostic (1.42e-1)" "unprognostic (4.38e-2)" "unprognostic (8.36e-2)" "unprognostic (9.71e-2)" "unprognostic (1.89e-1)" "unprognostic (2.44e-1)" "unprognostic (3.45e-1)" "unprognostic (2.19e-2)" "unprognostic (1.43e-1)" "unprognostic (3.55e-1)" "prognostic favorable (2.36e-8)" "unprognostic (4.69e-2)" "unprognostic (2.76e-1)" "unprognostic (8.84e-3)" "unprognostic (2.12e-1)" 34.7 31.4 39.9 20.9 42.4 26.7 31.8 39.1 41.4 29.3 17.4 59.7 41.9 37.0 12.7 57.3 26.2 21.8 270.4 34.7 43.0 36.5 58.5 31.1 19.8 41.1 44.8 27.0 22.5 76.7 28.7 27.6 40.6 36.3 38.1 35.0 32.2 62.3 310.5 58.9 46.3 41.2 43.5 31.5 44.9 25.4 48.8 26.1 56.1 337.6 30.4 51.2 36.2 40.5 93.6 54.0 52.6 72.7 59.7 47.2 58.8 76.0 66.1 96.5 72.6 88.7 51.8 68.8 74.8 92.6 60.6 80.5 101.7 156.1 90.6 60.6 75.4 94.5 81.8 54.2 53.8 114.2 51.9 57.0 105.1 133.1 124.5 40.1 66.2 26.4 106.1 53.6 69.7 30.2 60.2 15.2 39.7 57.8 77.4 68.2 95.8 58.5 44.9 61.4 68.2 44.6 88.4 81.0 74.6 41.4 43.8 49.2 71.2 63.1 58.3 88.4 71.2 59.0 86.4 120.7 69.0 99.6 69.8 10.4 11.5 7.6 8.9 14.0 10.2 6.7 6.7 7.9 9.7 4.8 5.0 6.2 16.2 6.2 18.3 4.2 8.1 15.7 39.9 42.4 39.1 41.4 34.7 43.0 41.1 44.8 40.6 43.5 48.8 40.5 18.1 22.4 15.8 16.6 10.2 22.8 9.4 18.9 19.9 26.7 17.4 16.4 336.9 7.2 14.9 14.7 12.5 15.1 12.5 39.2 21.5 13.6 4.7 8.9 12.1 18.5 18.0 32.4 21.5 20.4 15.5 17.3 17.3 12.8 10.8 12.8 11.7 46.3 16.0 30.3 24.5 22.2 18.3 23.9 9.7 8.0 7.2 19.1 17.8 8.4 17.3 14.6 8.2 11.1 16.7 18.5 16.8 15.1 10.9 13.9 41.8 14.3 12.9 21.0 13.1 16.0 16.5 25.9 15.6 25.1 30.1 25.2 10.3 12.5 26.4 16.6 MGARP "C4orf49, CESP-1, HUMMR, OSAP" ENSG00000137463 "Mitochondria localized glutamic acid rich protein" Q8TDB4 4 139266165-139280225 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adrenal gland: 228.0;retina: 116.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 151.3;Granulosa cells: 93.5;Horizontal cells: 208.6;Muller glia cells: 508.9;Theca cells: 474.8" "Cancer enhanced" "Detected in some" "renal cancer: 4.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 20.4;fHDF/TERT166: 30.7;HHSteC: 23.6;HUVEC TERT2: 61.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA015994, HPA070835" Enhanced Supported Mitochondria NA NA "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 5: Muller glia cells - Visual perception" Mitochondria "HPA015994: AB_2630370, HPA070835: " "unprognostic (2.68e-1)" "unprognostic (1.73e-1)" "unprognostic (8.18e-2)" "unprognostic (4.25e-2)" "unprognostic (3.54e-2)" "unprognostic (3.11e-2)" "unprognostic (3.42e-2)" "unprognostic (1.02e-3)" "unprognostic (2.90e-2)" "unprognostic (4.96e-2)" "unprognostic (1.50e-2)" "unprognostic (1.31e-1)" "unprognostic (4.08e-2)" "unprognostic (1.47e-2)" "unprognostic (9.91e-2)" "unprognostic (2.09e-2)" "unprognostic (2.36e-1)" 9.4 228.0 3.2 0.3 3.2 0.1 1.8 7.8 4.6 2.0 3.1 1.0 0.2 5.0 1.8 0.4 2.2 0.9 3.0 3.1 4.0 1.8 0.2 0.7 0.9 3.7 4.0 23.9 0.3 0.2 11.8 0.3 3.7 2.6 0.3 116.9 0.4 4.0 0.8 0.4 0.3 3.8 3.2 0.8 0.4 8.6 3.6 0.3 0.8 0.3 0.6 1.1 2.5 3.6 0.0 1.1 0.6 0.5 1.5 0.7 0.1 20.4 0.1 3.0 0.1 0.1 0.2 0.1 0.2 30.7 8.7 0.5 4.4 0.1 1.7 0.0 2.0 0.0 0.1 0.2 23.6 0.2 0.2 7.2 0.7 3.3 0.2 7.1 61.7 0.2 0.4 0.4 5.1 0.1 0.8 0.5 1.1 0.4 0.1 0.1 0.0 0.0 0.7 0.3 0.6 1.2 0.0 0.0 0.2 0.3 0.0 0.4 0.5 0.1 0.1 0.0 0.0 0.8 0.7 0.5 8.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 3.2 3.2 7.8 4.6 3.1 4.0 3.7 4.0 3.7 3.2 3.6 3.6 0.6 0.0 0.0 0.0 0.2 1.7 0.7 0.4 1.2 151.3 0.7 10.8 3.5 0.0 0.1 0.0 8.4 0.2 0.3 0.1 1.9 0.0 0.3 0.8 1.2 1.1 0.0 0.0 1.3 0.0 0.2 10.7 0.0 0.3 0.0 93.5 0.4 0.4 0.5 208.6 2.5 0.0 0.0 0.0 0.3 0.6 17.1 0.6 0.0 0.0 0.0 508.9 2.1 5.0 0.7 0.1 0.0 24.8 0.3 0.3 0.1 9.2 0.0 32.6 0.0 1.9 3.4 0.8 0.4 0.7 0.9 0.3 0.6 474.8 0.1 0.3 MGME1 "bA504H3.4, C20orf72, DDK1" ENSG00000125871 "Mitochondrial genome maintenance exonuclease 1" Q9BQP7 20 17969018-17991122 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Exonuclease, Hydrolase, Nuclease" "Disease variant, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040913 Approved Supported Mitochondria NA Yes "Cluster 2: Granulocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 6: Erythroid cells - Oxygen transport" Mitochondria "HPA040913: AB_10962835" "unprognostic (5.81e-3)" "unprognostic (5.96e-2)" "unprognostic (1.28e-1)" "unprognostic (1.29e-3)" "unprognostic (5.42e-2)" "unprognostic (1.44e-2)" "prognostic unfavorable (6.98e-8)" "unprognostic (5.31e-2)" "unprognostic (7.05e-2)" "unprognostic (2.91e-2)" "unprognostic (1.06e-2)" "unprognostic (7.45e-2)" "prognostic unfavorable (1.13e-7)" "unprognostic (2.04e-1)" "unprognostic (3.22e-2)" "unprognostic (8.70e-2)" "unprognostic (6.89e-2)" 6.5 14.4 7.5 11.7 8.2 16.0 18.4 8.0 9.7 7.3 7.9 11.4 13.4 5.2 10.4 13.1 6.2 7.3 10.8 7.2 7.5 12.8 14.4 7.7 19.9 8.6 8.1 5.9 8.8 7.8 4.7 12.8 8.7 7.5 13.4 7.8 9.0 7.4 21.3 34.2 11.9 6.7 8.3 17.7 9.3 10.7 7.9 19.8 11.9 12.1 20.8 8.9 9.5 9.3 44.7 51.0 41.0 38.7 16.5 29.0 54.9 36.8 27.1 34.8 47.4 63.4 44.7 53.4 20.3 16.4 39.6 64.9 43.1 55.1 52.7 19.9 34.7 34.7 29.6 97.2 12.3 22.9 56.2 17.6 37.3 52.3 27.4 16.3 28.2 26.0 48.0 33.3 70.7 33.4 40.5 29.9 36.3 26.8 44.0 30.5 91.4 50.8 30.1 32.3 31.6 26.1 26.1 62.8 57.7 33.2 59.7 15.5 22.8 59.1 48.1 29.8 40.3 24.6 59.6 45.3 15.2 17.3 44.7 57.5 15.2 44.6 8.1 14.9 10.9 21.0 10.5 10.9 12.6 24.2 7.5 6.9 14.4 16.7 15.0 19.5 17.1 8.4 7.5 8.2 8.0 9.7 7.2 7.5 8.6 8.1 8.7 8.3 7.9 9.3 10.6 0.0 10.0 19.9 24.6 46.4 15.7 12.7 40.9 7.9 19.9 39.4 12.6 15.7 11.9 7.3 8.4 22.9 21.0 14.3 39.2 13.1 9.8 11.2 15.6 11.9 7.2 52.6 3.1 10.2 25.9 8.1 5.1 13.3 48.0 25.5 20.0 9.9 31.4 8.4 2.9 12.1 6.1 34.4 15.4 5.5 8.4 18.8 21.4 9.4 16.4 11.4 28.8 17.6 12.6 10.4 10.6 5.7 13.2 12.3 31.0 26.5 5.9 10.0 13.1 10.3 10.8 38.6 47.0 20.5 46.9 18.1 14.9 27.1 19.0 12.8 MICOS10 "C1orf151, FLJ36999, Mic10, MINOS1, MIO10, RP5-1056L3.2" ENSG00000173436 "Mitochondrial contact site and cristae organizing system subunit 10" Q5TGZ0 1 19484403-19629821 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 453.9;Cytotrophoblasts: 283.4;Extravillous trophoblasts: 279.7;Hofbauer cells: 531.0;Syncytiotrophoblasts: 183.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA059930 Enhanced Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 24: Non-specific - Transcription regulation" Mitochondria "HPA059930: AB_2684167" "unprognostic (3.84e-2)" "unprognostic (8.74e-3)" "unprognostic (2.66e-2)" "unprognostic (3.03e-1)" "unprognostic (1.35e-1)" "unprognostic (6.98e-2)" "prognostic unfavorable (7.23e-4)" "unprognostic (2.88e-1)" "unprognostic (8.74e-2)" "unprognostic (3.96e-1)" "unprognostic (1.37e-1)" "unprognostic (2.43e-2)" "unprognostic (1.24e-3)" "unprognostic (7.13e-2)" "unprognostic (1.20e-1)" "unprognostic (2.03e-2)" "prognostic favorable (8.11e-4)" 4.9 5.0 11.5 3.1 11.6 2.6 6.0 11.9 13.6 8.6 11.0 9.3 5.1 7.0 6.2 7.2 7.3 4.1 12.6 11.5 13.1 9.7 4.0 4.6 4.3 12.9 11.7 6.4 5.2 11.1 9.5 4.0 13.1 8.5 8.8 5.9 5.1 8.3 14.3 4.8 6.0 7.0 11.3 3.6 6.7 3.4 13.8 4.0 6.5 16.8 5.9 7.0 6.2 11.1 10.0 13.3 7.3 8.4 13.7 13.6 4.5 8.3 9.6 9.5 10.1 9.3 8.7 8.1 6.8 11.0 7.7 6.9 12.8 10.9 15.2 12.7 9.1 7.1 21.2 13.0 6.0 11.6 5.1 10.7 17.5 9.5 11.6 7.4 14.1 6.0 15.8 5.9 14.4 17.2 5.8 15.0 6.2 12.5 16.7 5.7 9.3 10.8 23.3 5.9 15.4 6.7 9.6 7.4 7.1 5.7 7.1 6.7 9.3 7.4 5.7 9.5 8.3 3.8 6.8 8.4 5.8 21.3 7.1 3.8 4.8 5.7 3.6 6.6 3.3 4.3 4.9 4.1 5.1 4.1 6.3 4.5 3.2 2.3 7.0 5.0 4.9 5.9 11.5 11.6 11.9 13.6 11.5 13.1 12.9 11.7 13.1 11.3 13.8 11.1 63.3 0.0 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 453.9 0.0 0.0 0.0 0.0 283.4 25.0 0.0 0.0 0.0 0.0 0.0 0.0 27.1 0.0 0.0 0.0 0.0 279.7 52.8 0.0 0.0 0.0 0.0 0.0 0.0 531.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.7 0.0 0.0 0.0 0.0 183.5 5.3 0.0 0.0 0.0 MICU1 "CALC, CBARA1, EFHA3, FLJ12684" ENSG00000107745 "Mitochondrial calcium uptake 1" Q9BPX6 10 72367327-72626191 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Calcium transport, Ion transport, Transport" Allergen "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 185.5;Inhibitory neurons: 205.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037479, HPA037480" Approved Supported Mitochondria NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA037479: AB_2675495, HPA037480: AB_10696934" "unprognostic (8.18e-2)" "unprognostic (6.98e-3)" "unprognostic (6.71e-2)" "unprognostic (8.06e-2)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" "unprognostic (8.91e-2)" "unprognostic (3.60e-2)" "unprognostic (2.96e-3)" "unprognostic (3.38e-2)" "unprognostic (7.43e-2)" "unprognostic (2.23e-2)" "prognostic favorable (4.66e-7)" "unprognostic (1.70e-1)" "unprognostic (1.55e-1)" "unprognostic (5.35e-2)" "unprognostic (6.70e-2)" 30.9 55.3 34.4 21.2 37.2 34.2 26.4 51.4 47.1 28.8 27.8 30.1 37.4 36.5 23.8 20.7 34.6 32.3 43.9 37.8 32.2 105.3 116.7 29.6 20.1 32.2 30.7 41.6 20.0 43.3 24.4 23.6 33.7 24.8 32.9 31.5 20.8 22.3 72.2 29.0 32.7 38.4 29.0 27.0 43.3 20.2 30.4 26.1 22.9 76.9 21.6 30.8 21.7 34.1 42.2 71.8 45.4 53.3 70.8 66.6 20.6 45.8 101.6 65.7 89.8 42.2 77.2 56.8 37.3 63.5 54.0 49.1 57.7 40.7 76.9 51.9 46.6 38.3 37.1 61.2 56.4 53.3 40.1 66.6 36.2 72.4 66.5 90.4 57.7 53.4 60.0 64.5 77.6 37.9 46.7 49.9 19.0 45.0 17.3 50.5 60.9 37.4 80.8 31.0 34.8 49.8 54.2 65.9 42.0 45.2 39.3 50.5 36.2 32.6 50.1 65.7 38.4 33.9 62.6 39.2 65.1 69.6 22.5 21.5 60.0 110.8 16.8 49.8 14.7 15.1 14.7 15.5 26.0 17.5 14.4 12.0 48.8 15.2 54.5 16.5 15.3 35.4 34.4 37.2 51.4 47.1 37.8 32.2 32.2 30.7 33.7 29.0 30.4 34.1 30.4 54.5 36.0 47.7 23.4 9.9 16.0 22.6 14.2 31.9 25.3 19.6 35.8 25.8 38.3 35.0 20.9 20.7 16.9 25.9 80.3 35.6 10.7 42.0 43.0 22.7 14.4 25.0 185.5 26.7 18.8 31.1 45.9 48.2 18.3 31.5 23.9 60.4 34.8 16.8 205.9 24.4 16.2 36.9 13.4 12.5 26.8 40.1 12.4 64.6 38.0 51.3 10.3 146.8 97.5 51.4 24.9 25.9 25.0 10.7 29.3 110.7 34.0 33.8 6.6 29.0 27.2 54.5 40.0 14.2 14.2 21.5 19.0 73.4 23.6 14.2 MIGA1 "FAM73A, FLJ35093" ENSG00000180488 "Mitoguardin 1" Q8NAN2 1 77779624-77879539 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 33.2;Alveolar cells type 1: 35.3;Breast glandular cells: 28.1;Glandular and luminal cells: 29.1;Proximal tubular cells: 31.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017589 Approved Supported Mitochondria NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 18: U-2197 - ECM organization" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA017589: AB_1848409" "unprognostic (3.27e-1)" "unprognostic (1.19e-2)" "unprognostic (7.31e-3)" "unprognostic (4.62e-3)" "unprognostic (2.40e-1)" "unprognostic (3.48e-2)" "unprognostic (2.70e-2)" "unprognostic (7.27e-2)" "unprognostic (1.88e-1)" "unprognostic (1.02e-1)" "unprognostic (1.30e-1)" "unprognostic (6.82e-2)" "unprognostic (3.13e-3)" "unprognostic (1.89e-1)" "unprognostic (1.68e-1)" "unprognostic (4.71e-2)" "unprognostic (4.75e-2)" 8.8 7.9 6.0 5.4 10.3 6.8 14.2 8.2 9.1 7.2 0.0 6.2 7.3 8.8 5.2 6.3 6.5 7.7 6.5 6.7 9.3 14.9 8.5 6.1 5.3 10.8 9.0 9.0 6.1 18.9 3.4 7.7 11.0 9.6 5.7 5.6 9.2 6.6 7.1 4.6 8.1 7.4 9.5 5.9 7.5 5.2 8.5 4.5 16.5 9.4 4.2 6.0 3.6 19.3 11.8 7.5 4.6 5.9 11.1 14.3 12.1 16.7 7.8 9.6 9.8 7.7 8.0 5.1 18.0 11.5 11.6 7.9 6.3 9.9 18.0 7.4 6.4 6.0 8.9 3.9 11.4 5.6 4.5 10.4 10.5 19.7 14.2 13.8 9.8 4.5 3.4 6.7 14.8 1.9 5.5 3.2 3.9 5.8 9.2 2.9 11.3 2.6 11.6 12.5 9.2 7.4 7.7 11.4 21.8 7.6 4.4 3.6 15.8 13.7 6.3 20.9 17.6 4.0 6.0 3.2 12.1 4.8 6.0 3.7 2.2 2.7 2.1 2.7 2.2 1.7 1.6 1.7 1.5 2.1 2.4 2.1 1.2 2.4 1.7 1.1 1.7 1.2 6.0 10.3 8.2 9.1 6.7 9.3 10.8 9.0 11.0 9.5 8.5 19.3 33.2 35.3 26.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 28.1 20.6 0.0 0.0 10.5 23.9 0.0 17.0 16.5 0.0 5.9 16.4 0.0 15.6 27.0 9.9 0.0 0.0 0.0 14.7 14.0 12.9 0.0 29.1 12.6 18.8 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 2.6 0.0 0.0 0.0 0.0 18.9 0.0 0.0 5.5 0.0 0.0 31.2 8.7 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 13.3 7.5 16.2 0.0 0.0 MIPEP MIP ENSG00000027001 "Mitochondrial intermediate peptidase" Q99797 13 23730189-23889400 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 108.0;Oligodendrocytes: 62.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 64.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030676, HPA031669, HPA031670" Approved Enhanced Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA030676: AB_10598907, HPA031669: AB_10600986, HPA031670: AB_10602198" "unprognostic (2.05e-1)" "unprognostic (3.17e-2)" "unprognostic (3.75e-3)" "unprognostic (3.72e-2)" "unprognostic (1.24e-1)" "unprognostic (1.23e-1)" "unprognostic (2.41e-1)" "unprognostic (2.21e-1)" "unprognostic (4.69e-2)" "unprognostic (1.12e-1)" "unprognostic (7.54e-2)" "unprognostic (4.76e-1)" "prognostic favorable (7.66e-12)" "unprognostic (1.62e-2)" "unprognostic (4.95e-2)" "unprognostic (2.79e-1)" "unprognostic (6.90e-3)" 6.3 9.6 3.7 6.2 4.3 5.3 11.1 3.2 5.0 7.5 13.4 12.9 8.8 7.2 12.4 11.5 17.3 7.7 18.4 14.4 4.0 25.4 12.0 7.1 5.1 4.0 5.0 5.4 8.2 14.6 5.4 4.7 4.6 10.9 13.1 6.1 9.7 8.7 13.9 21.4 7.6 7.8 4.0 4.3 8.6 9.8 3.7 6.0 11.1 16.9 7.8 7.7 6.4 4.9 14.6 16.1 7.8 18.4 17.4 23.4 16.6 10.3 16.0 15.1 12.7 21.7 28.1 17.0 10.2 8.4 13.3 35.8 18.1 21.6 18.8 9.9 11.5 7.4 7.0 18.8 14.3 17.5 3.9 11.6 26.4 15.7 13.9 12.7 19.2 12.7 14.5 2.7 24.0 10.8 12.6 9.8 10.8 64.8 16.1 13.8 21.0 14.8 33.7 9.6 18.2 6.1 11.0 17.8 21.8 9.8 18.3 9.7 10.7 9.2 7.6 15.3 11.2 2.6 4.0 9.1 15.9 8.8 11.7 0.0 3.0 1.3 7.4 3.7 9.3 8.7 7.1 6.8 6.5 7.2 6.7 6.7 0.0 10.3 12.0 5.5 5.2 4.0 3.7 4.3 3.2 5.0 14.4 4.0 4.0 5.0 4.6 4.0 3.7 4.9 2.5 16.0 8.6 18.9 5.9 39.9 7.7 13.8 6.2 3.6 6.2 5.8 108.0 11.5 12.6 9.2 6.2 9.8 2.4 8.2 29.4 23.4 8.2 26.0 8.5 5.4 6.0 4.6 43.8 10.6 9.3 8.0 7.1 8.5 2.5 4.2 3.6 5.9 9.7 15.2 47.5 7.1 14.2 3.5 5.0 7.4 6.8 4.3 5.4 12.2 3.4 5.5 5.2 18.1 62.8 8.6 7.0 8.6 4.9 7.5 6.6 25.6 46.3 11.4 0.0 7.3 5.7 9.7 19.0 10.1 42.3 5.1 4.0 8.9 13.6 5.6 MMAB "cblB, CFAP23" ENSG00000139428 "Metabolism of cobalamin associated B" Q96EY8 12 109553715-109573580 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 103.6" "Cell type enhanced" "Detected in all" "Hepatocytes: 225.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039017 Supported Approved Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 15: Hepatocytes - Hemostasis" Mitochondria "HPA039017: AB_10673603" "unprognostic (1.16e-1)" "unprognostic (1.25e-2)" "unprognostic (1.90e-1)" "unprognostic (1.79e-1)" "unprognostic (4.38e-2)" "unprognostic (2.10e-1)" "unprognostic (1.38e-1)" "unprognostic (4.22e-1)" "unprognostic (2.04e-2)" "unprognostic (5.15e-2)" "unprognostic (1.47e-3)" "unprognostic (2.58e-1)" "prognostic favorable (1.55e-4)" "unprognostic (4.90e-2)" "unprognostic (1.51e-1)" "unprognostic (2.23e-1)" "unprognostic (9.65e-2)" 15.5 51.2 17.8 6.3 18.3 5.8 15.8 18.8 26.9 12.4 18.6 15.8 13.0 10.7 21.2 29.1 13.0 6.0 30.0 17.0 18.8 32.8 103.6 14.9 6.2 22.2 19.0 18.9 23.0 9.8 20.5 4.9 21.3 26.5 7.9 7.3 17.1 6.3 21.1 18.2 14.0 5.6 19.0 12.4 17.7 12.6 18.9 5.5 22.1 16.2 6.5 14.1 14.7 22.9 32.2 22.3 22.2 17.6 8.8 17.7 11.3 7.1 16.2 10.3 10.8 25.8 29.5 21.0 19.9 8.0 19.1 32.9 14.6 54.9 4.6 8.2 60.9 8.6 15.9 42.1 31.3 18.4 7.2 24.0 33.5 22.2 9.7 12.3 9.7 16.4 27.5 15.5 7.3 74.7 16.6 29.2 27.3 3.3 31.6 13.6 8.7 53.9 45.3 30.3 34.1 14.8 15.8 29.2 12.7 6.2 60.5 50.5 5.4 8.6 3.6 6.1 10.4 11.9 9.6 24.0 19.0 22.2 23.9 7.4 7.2 1.0 15.3 10.0 12.2 13.6 11.1 12.1 11.3 17.8 15.2 14.6 1.9 11.2 10.9 9.2 5.8 10.3 17.8 18.3 18.8 26.9 17.0 18.8 22.2 19.0 21.3 19.0 18.9 22.9 25.1 35.3 80.8 9.8 20.4 10.3 33.1 105.6 17.1 32.9 59.6 47.0 52.3 60.1 68.9 42.3 29.2 55.4 15.2 33.6 150.6 49.7 41.3 23.8 10.0 22.1 33.0 34.1 6.4 71.3 37.6 24.7 28.5 16.5 16.5 34.3 28.5 225.3 34.8 104.3 8.5 50.4 71.2 20.4 10.2 82.9 40.4 13.5 26.6 4.7 25.1 30.6 30.9 6.6 21.5 29.7 30.0 30.5 18.1 31.8 61.9 143.6 62.1 29.7 13.1 17.9 26.3 26.0 15.8 44.7 19.7 61.8 16.1 121.1 56.6 30.3 MPC1 "BRP44L, CGI-129, dJ68L15.3, SLC54A1" ENSG00000060762 "Mitochondrial pyruvate carrier 1" Q9Y5U8 6 166364919-166383013 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 739.7;tongue: 559.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 950.0;Distal tubular cells: 1721.8;Proximal tubular cells: 573.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045119, HPA055790" Enhanced Enhanced Mitochondria NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA045119: AB_10960421, HPA055790: AB_2682923" "unprognostic (3.30e-2)" "prognostic favorable (1.45e-4)" "unprognostic (5.24e-3)" "unprognostic (1.68e-1)" "unprognostic (3.17e-2)" "unprognostic (2.85e-2)" "unprognostic (7.61e-2)" "prognostic favorable (1.29e-4)" "unprognostic (3.27e-1)" "unprognostic (1.19e-1)" "unprognostic (1.11e-3)" "unprognostic (5.64e-2)" "prognostic favorable (4.79e-11)" "unprognostic (4.13e-2)" "unprognostic (1.03e-1)" "unprognostic (7.48e-2)" "unprognostic (8.45e-2)" 61.7 39.6 105.9 33.4 119.5 57.0 52.8 129.7 153.1 52.4 108.0 97.7 84.8 35.7 44.8 71.5 34.7 41.7 739.7 101.2 127.8 259.9 411.2 44.6 44.3 119.2 123.9 43.4 66.0 141.8 38.1 23.7 119.5 43.5 89.9 57.3 87.7 42.3 319.4 40.9 63.8 38.5 117.1 35.0 96.1 22.2 121.5 48.6 82.9 559.2 44.2 47.4 34.9 132.4 25.6 7.5 31.3 107.7 88.4 49.8 45.2 29.1 47.1 45.1 43.9 38.8 17.9 53.6 50.9 45.4 36.1 24.5 47.0 36.7 31.9 36.1 79.0 27.5 35.4 132.6 36.6 104.9 34.1 40.0 51.0 36.8 26.7 13.7 36.9 80.8 94.2 84.1 28.6 40.5 73.1 193.7 16.1 148.0 35.5 39.1 51.7 134.9 85.4 20.5 96.7 85.7 33.6 145.8 34.0 25.9 34.5 154.3 25.3 25.7 26.8 91.6 30.0 55.8 42.2 46.3 23.5 127.0 42.1 60.7 60.0 90.1 41.7 98.3 39.4 33.1 48.5 45.1 72.2 25.4 44.7 43.3 54.6 40.5 128.5 43.0 69.1 49.8 105.9 119.5 129.7 153.1 101.2 127.8 119.2 123.9 119.5 117.1 121.5 132.4 56.1 118.6 48.0 64.6 51.7 45.6 44.2 83.6 29.0 61.1 74.2 79.1 950.0 187.3 67.6 106.7 10.4 22.0 54.2 219.1 1721.8 89.3 66.8 73.7 50.7 51.7 37.2 72.6 49.0 140.3 78.3 74.1 63.7 93.2 71.0 28.0 47.5 391.0 121.4 48.8 74.7 122.1 166.8 89.6 81.7 10.2 66.5 80.3 129.9 20.6 104.7 199.9 58.7 32.2 108.0 65.2 125.0 89.9 114.5 32.0 162.0 573.6 46.3 66.7 92.1 76.9 80.4 163.2 79.6 67.3 55.8 24.4 58.4 39.9 146.7 53.6 MRM1 FLJ22578 ENSG00000278619 "Mitochondrial rRNA methyltransferase 1" Q6IN84 17 36601583-36608964 "Metabolic proteins, Predicted intracellular proteins" "rRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA021598 Supported Supported Mitochondria NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Mitochondria "HPA021598: AB_1854097" "unprognostic (9.07e-3)" "unprognostic (1.50e-1)" "unprognostic (1.86e-1)" "unprognostic (1.19e-1)" "unprognostic (4.86e-2)" "unprognostic (1.43e-1)" "unprognostic (1.08e-2)" "unprognostic (2.46e-1)" "unprognostic (1.42e-1)" "unprognostic (4.90e-2)" "unprognostic (2.47e-2)" "unprognostic (8.56e-2)" "unprognostic (2.75e-1)" "unprognostic (5.67e-2)" "unprognostic (2.36e-1)" "unprognostic (3.95e-1)" "unprognostic (1.74e-2)" 3.4 6.0 2.2 1.1 2.6 2.1 3.9 1.8 4.5 4.5 1.1 6.0 2.8 4.5 1.4 5.2 4.1 0.3 7.4 2.0 2.3 5.7 7.3 2.8 3.0 2.2 2.2 5.0 6.2 2.6 2.9 0.7 2.3 4.8 3.1 0.6 4.1 2.4 8.1 3.6 6.0 0.7 1.8 5.9 4.6 2.3 2.5 1.9 4.2 4.7 0.6 5.8 4.3 2.6 1.5 8.7 0.0 5.0 4.3 5.1 15.5 0.3 0.0 0.0 0.0 0.7 0.2 0.7 9.5 0.0 4.0 20.0 0.2 0.4 0.0 7.5 2.9 15.2 5.1 8.9 2.2 7.9 7.5 4.0 0.4 10.2 0.0 1.4 5.2 6.7 9.9 4.9 6.0 0.2 14.6 4.6 0.2 19.9 0.1 12.1 0.0 19.5 4.4 9.3 4.1 3.1 0.0 6.1 6.5 5.5 6.8 2.6 2.0 5.0 8.9 5.7 0.1 11.9 15.3 6.5 0.0 8.0 4.0 0.0 2.0 0.0 2.8 3.0 5.3 4.4 2.2 2.7 2.1 3.9 3.5 3.8 0.0 6.0 1.5 2.4 2.0 2.4 2.2 2.6 1.8 4.5 2.0 2.3 2.2 2.2 2.3 1.8 2.5 2.6 1.3 0.0 1.5 4.9 3.8 1.1 2.9 2.7 2.8 1.1 2.6 1.7 7.8 2.8 1.6 3.7 4.2 7.0 0.6 5.3 9.8 4.2 0.1 1.0 2.9 2.9 1.8 5.0 9.6 1.8 7.4 1.8 3.1 1.3 0.0 3.9 1.8 2.1 6.2 6.7 8.2 5.3 2.0 1.0 0.4 0.0 3.4 1.5 1.8 0.0 2.2 1.7 2.1 5.5 4.0 2.2 5.4 1.5 2.2 5.6 5.4 5.1 0.6 1.2 0.0 1.9 2.0 1.3 3.0 3.3 0.4 1.8 2.2 4.5 9.0 2.2 MRM3 "FLJ10581, HC90, RMTL1, RNMTL1" ENSG00000171861 "Mitochondrial rRNA methyltransferase 3" Q9HC36 17 782353-792509 "Metabolic proteins, Predicted intracellular proteins" "rRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 27.1;Distal tubular cells: 19.6;Ductal cells: 18.9;Exocrine glandular cells: 18.4;Extravillous trophoblasts: 24.6;Proximal tubular cells: 20.0;Syncytiotrophoblasts: 19.6;Theca cells: 28.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022534, HPA023031, HPA023292" Enhanced Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA022534: AB_1856386, HPA023031: AB_1856387, HPA023292: AB_1856388" "unprognostic (1.66e-1)" "unprognostic (5.83e-3)" "unprognostic (6.72e-2)" "prognostic favorable (2.81e-4)" "unprognostic (2.67e-1)" "unprognostic (1.83e-1)" "unprognostic (2.48e-1)" "unprognostic (1.54e-1)" "unprognostic (1.46e-1)" "unprognostic (8.20e-2)" "unprognostic (3.72e-3)" "unprognostic (8.47e-2)" "prognostic favorable (3.00e-4)" "unprognostic (3.82e-2)" "unprognostic (9.98e-2)" "unprognostic (1.05e-2)" "unprognostic (1.42e-2)" 9.3 12.9 7.9 6.8 8.4 17.6 8.7 9.9 9.2 6.7 9.7 9.7 7.8 7.6 5.2 11.6 8.0 4.8 17.3 8.2 7.9 9.7 20.5 6.0 10.4 8.2 8.7 8.7 19.6 9.1 6.2 6.9 8.6 7.5 7.5 4.3 9.5 6.0 29.4 14.7 8.2 6.6 7.7 9.9 13.0 18.6 8.6 8.3 7.0 18.7 9.3 8.6 7.2 8.3 26.4 53.9 11.3 19.8 16.2 13.8 22.5 13.6 12.8 27.3 22.8 31.8 12.0 47.3 14.1 10.6 13.1 21.7 33.0 12.0 24.8 16.2 55.9 18.3 30.6 27.9 16.7 15.8 16.0 16.7 16.2 29.0 23.9 13.6 20.7 28.3 31.3 20.1 14.5 28.5 27.5 20.8 16.9 19.3 28.2 33.1 7.9 25.3 18.2 14.2 15.1 17.6 19.8 16.6 26.5 9.0 20.6 14.2 16.6 14.6 11.2 21.0 38.3 8.0 11.8 18.9 18.3 22.1 20.0 12.5 24.6 14.7 25.0 20.6 27.0 38.2 27.1 30.8 25.8 38.4 32.8 28.4 1.8 32.7 21.1 20.8 31.9 26.8 7.9 8.4 9.9 9.2 8.2 7.9 8.2 8.7 8.6 7.7 8.6 8.3 11.3 6.4 1.1 0.0 4.2 0.0 0.0 0.0 0.0 0.0 9.8 10.4 0.0 0.0 1.3 5.5 0.0 27.1 7.6 0.0 19.6 18.9 0.0 8.3 8.0 5.1 0.0 0.0 0.0 18.4 24.6 4.1 0.0 8.8 3.8 15.6 0.0 0.0 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 14.2 0.0 0.0 0.5 0.0 0.0 20.0 0.7 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 19.6 4.4 28.9 0.0 0.0 MRPL1 BM022 ENSG00000169288 "Mitochondrial ribosomal protein L1" Q9BYD6 4 77862830-77952785 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043656 Supported Approved Mitochondria NA NA "Cluster 37: B-cells - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA043656: AB_2678601" "unprognostic (9.03e-3)" "unprognostic (3.25e-1)" "unprognostic (1.11e-3)" "unprognostic (2.88e-1)" "unprognostic (4.52e-2)" "unprognostic (5.29e-3)" "unprognostic (4.69e-3)" "unprognostic (5.44e-2)" "unprognostic (1.66e-2)" "unprognostic (5.14e-3)" "unprognostic (8.79e-2)" "unprognostic (2.22e-2)" "prognostic favorable (3.35e-5)" "unprognostic (7.63e-2)" "unprognostic (1.87e-1)" "unprognostic (7.13e-2)" "unprognostic (9.17e-3)" 19.4 17.7 17.1 17.4 17.7 26.9 24.4 16.8 20.9 16.5 15.7 28.3 19.5 18.6 21.0 20.5 17.0 11.8 41.7 17.9 18.2 38.1 33.8 13.1 23.6 17.3 17.1 19.0 14.1 21.4 8.1 21.4 17.9 16.0 29.4 14.5 19.3 15.0 67.3 14.6 18.6 21.4 17.1 15.0 17.8 8.8 17.8 19.3 17.7 67.6 24.2 19.8 9.2 17.7 40.5 26.2 47.3 40.7 36.6 47.4 41.2 44.6 28.6 57.4 39.3 55.0 71.6 71.4 53.9 37.1 35.8 32.8 71.1 82.5 75.6 47.6 37.6 61.1 27.6 60.4 47.5 126.2 28.3 37.7 76.7 51.2 53.0 37.8 70.4 50.1 90.3 24.1 73.6 46.0 76.0 84.9 52.0 92.0 34.3 90.7 60.6 41.1 113.3 43.2 52.1 25.9 36.1 88.7 84.5 38.0 43.7 61.0 41.9 37.5 54.3 37.7 65.1 21.1 28.1 74.6 31.9 71.8 49.3 9.0 11.5 7.0 20.6 19.0 20.6 27.8 22.2 23.1 22.1 25.5 26.8 29.5 1.7 23.2 16.9 18.0 25.8 15.4 17.1 17.7 16.8 20.9 17.9 18.2 17.3 17.1 17.9 17.1 17.8 17.7 40.1 25.6 35.7 22.5 45.7 12.7 17.1 68.6 13.6 24.6 31.6 37.2 122.1 57.2 33.5 33.1 18.8 72.7 75.5 22.2 135.0 46.0 15.5 33.9 40.9 34.9 47.9 34.9 45.9 36.7 51.9 27.5 18.8 38.5 42.4 38.7 40.7 134.3 47.7 25.2 39.7 60.5 61.1 25.1 12.7 9.3 31.1 23.5 16.0 35.6 34.1 26.7 64.9 45.2 47.7 28.3 24.9 33.4 38.6 14.7 36.0 144.8 20.6 42.4 39.5 31.4 45.9 21.1 48.0 23.1 12.8 34.9 65.8 61.7 70.9 15.5 MRPL10 "L10MT, MGC17973, MRP-L10, MRP-L8, MRPL8, RPML8" ENSG00000159111 "Mitochondrial ribosomal protein L10" Q7Z7H8 17 47823272-47831541 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021234, HPA029885" Enhanced Enhanced Mitochondria NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" Mitochondria "HPA021234: AB_1854098, HPA029885: AB_2673233" "unprognostic (6.84e-3)" "unprognostic (1.03e-1)" "unprognostic (8.05e-2)" "unprognostic (9.09e-3)" "unprognostic (1.97e-1)" "unprognostic (4.01e-3)" "prognostic unfavorable (6.67e-4)" "unprognostic (5.21e-2)" "unprognostic (1.03e-1)" "unprognostic (8.91e-2)" "unprognostic (1.38e-1)" "unprognostic (6.16e-2)" "unprognostic (1.29e-1)" "unprognostic (2.82e-1)" "unprognostic (1.87e-2)" "unprognostic (1.60e-1)" "unprognostic (6.87e-2)" 32.1 32.8 35.6 14.4 36.6 24.7 29.7 36.9 39.7 30.1 33.2 40.9 25.6 31.4 22.8 27.1 29.8 21.9 58.1 34.9 36.7 31.2 29.9 20.1 26.2 36.5 36.0 48.8 41.0 28.9 17.3 23.2 36.2 24.8 23.1 21.7 22.1 25.5 64.2 23.8 26.7 26.5 35.7 28.2 36.2 20.1 37.4 25.9 23.1 52.4 26.9 37.9 25.4 36.8 36.8 80.0 33.4 33.0 78.3 71.3 61.6 32.2 54.0 54.2 46.4 155.7 49.2 59.1 71.9 42.0 36.0 33.6 48.3 62.6 48.0 57.6 76.4 47.2 41.7 110.0 67.4 42.8 25.5 80.8 53.2 64.4 90.7 63.7 52.9 58.4 64.8 56.6 42.3 73.3 43.2 55.0 55.1 64.0 76.5 34.7 63.7 66.5 59.9 35.8 39.2 63.2 23.9 26.9 68.7 62.9 81.2 45.5 32.3 47.5 39.0 32.3 45.1 100.1 82.4 48.0 41.4 32.3 32.4 29.8 37.3 18.5 61.6 39.6 59.1 31.8 42.4 55.3 43.0 36.6 35.6 42.2 14.5 26.6 32.9 26.0 52.5 42.0 35.6 36.6 36.9 39.7 34.9 36.7 36.5 36.0 36.2 35.7 37.4 36.8 17.1 6.4 13.6 4.2 19.2 12.5 20.8 42.5 27.9 15.3 25.3 31.5 31.5 20.0 19.5 14.7 6.2 90.5 50.9 17.9 46.9 43.8 22.0 7.9 16.3 21.7 8.5 30.3 5.4 54.7 60.0 23.3 20.4 11.0 8.8 31.8 20.7 15.6 41.7 32.0 6.6 20.7 32.6 31.4 10.8 30.5 24.5 17.3 16.0 2.8 31.8 24.4 44.3 7.1 8.2 40.4 14.7 24.0 22.8 18.4 30.8 47.5 6.1 13.7 6.6 17.5 28.0 23.2 29.2 24.1 12.5 77.3 48.5 49.4 31.9 18.8 MRPL11 ENSG00000174547 "Mitochondrial ribosomal protein L11" Q9Y3B7 11 66435075-66466738 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057685 Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA057685: AB_2683502" "unprognostic (1.96e-1)" "unprognostic (2.36e-1)" "unprognostic (2.21e-2)" "unprognostic (1.79e-2)" "unprognostic (9.30e-2)" "unprognostic (1.12e-2)" "unprognostic (1.81e-3)" "unprognostic (1.58e-1)" "unprognostic (4.87e-1)" "unprognostic (8.32e-3)" "unprognostic (2.85e-2)" "unprognostic (3.21e-1)" "unprognostic (1.31e-2)" "unprognostic (9.34e-2)" "unprognostic (6.36e-2)" "unprognostic (1.21e-1)" "unprognostic (1.72e-1)" 14.6 11.0 12.5 11.8 13.2 23.0 17.3 13.1 21.8 12.8 14.6 21.8 16.5 13.8 16.0 19.4 16.6 8.0 20.6 12.8 12.8 17.1 22.1 10.3 19.0 12.8 12.8 17.7 18.9 17.1 7.9 12.2 13.0 11.6 23.7 11.1 18.0 13.1 49.3 13.3 17.2 14.4 12.6 14.3 17.3 9.8 14.2 18.5 11.6 35.9 20.5 14.7 12.7 12.8 62.1 48.3 44.9 43.3 22.0 24.5 64.2 35.2 40.0 65.8 50.2 135.8 74.7 77.3 59.8 33.6 73.0 52.9 66.5 69.1 46.2 35.8 44.1 48.6 42.6 72.9 26.4 81.4 31.4 29.3 40.6 40.6 49.9 31.7 49.5 73.1 72.1 32.9 28.9 105.6 94.1 129.5 82.3 165.7 69.8 59.2 89.5 97.6 29.1 42.0 47.0 40.8 38.9 58.0 127.4 37.9 66.0 42.4 28.1 39.3 53.1 37.6 42.1 24.1 40.3 87.0 40.7 51.8 27.1 2.1 34.3 7.7 35.9 44.9 38.1 51.6 39.1 35.3 54.5 40.3 40.9 37.8 2.3 37.9 40.7 32.9 43.8 42.5 12.5 13.2 13.1 21.8 12.8 12.8 12.8 12.8 13.0 12.6 14.2 12.8 45.7 12.8 28.3 3.6 61.9 49.8 94.2 80.8 58.1 21.8 69.4 96.3 66.6 60.1 49.0 33.1 8.4 139.6 46.5 66.3 123.3 67.7 40.7 38.0 47.3 51.8 51.0 63.9 4.5 85.6 196.6 54.2 47.4 35.2 31.6 93.9 50.7 82.9 126.2 20.2 4.7 97.3 30.5 60.6 60.3 11.1 50.7 59.5 67.6 1.9 77.6 32.3 66.9 2.5 4.5 59.6 69.4 45.9 61.4 75.0 94.4 124.5 43.7 22.1 26.3 48.9 77.1 78.9 60.5 95.7 49.0 77.4 51.7 68.5 165.2 91.4 MRPL12 "MRPL7, MRPL7/L12, RPML12" ENSG00000262814 "Mitochondrial ribosomal protein L12" P52815 17 81703367-81707517 "Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 303.2;Undifferentiated cells: 364.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022853, HPA023043" Supported Supported Mitochondria NA NA 49000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA022853: AB_1854099, HPA023043: AB_1854100" "unprognostic (1.16e-1)" "unprognostic (1.65e-1)" "unprognostic (6.59e-2)" "unprognostic (1.66e-2)" "unprognostic (9.52e-2)" "unprognostic (5.97e-2)" "unprognostic (5.97e-3)" "prognostic unfavorable (2.35e-4)" "unprognostic (1.78e-1)" "unprognostic (6.47e-3)" "unprognostic (8.17e-2)" "unprognostic (3.07e-1)" "unprognostic (8.77e-3)" "unprognostic (3.41e-2)" "unprognostic (2.16e-1)" "unprognostic (1.18e-1)" "unprognostic (9.26e-2)" 57.8 73.7 39.4 28.4 39.9 31.0 44.0 46.8 51.9 34.4 50.4 79.7 47.3 39.1 11.0 96.8 35.1 10.9 209.9 39.0 42.2 86.9 184.9 34.9 25.5 40.7 43.1 26.7 60.6 45.9 39.1 19.5 41.0 44.9 37.3 7.3 48.1 21.5 169.7 51.1 51.3 20.6 38.8 53.8 57.9 32.3 46.2 20.1 34.0 148.1 27.7 45.4 46.5 39.4 153.6 256.8 67.5 78.2 50.2 55.0 124.3 117.0 71.3 173.2 128.3 216.5 71.6 236.5 69.2 77.5 116.7 127.1 87.6 150.7 87.6 55.9 438.3 181.1 140.2 246.5 74.0 200.5 90.9 63.4 108.5 119.4 132.4 55.4 146.1 115.6 179.4 75.6 87.1 194.2 171.6 295.9 106.0 165.9 330.6 160.7 109.5 176.4 129.8 126.1 171.4 220.7 86.1 366.1 199.8 69.1 186.2 180.5 76.7 131.0 155.8 103.4 241.2 146.2 54.3 137.0 89.3 143.0 100.6 17.7 63.1 9.0 37.9 84.8 52.6 66.2 37.8 42.6 93.7 62.1 39.2 36.0 6.9 43.5 49.8 77.0 35.8 48.9 39.4 39.9 46.8 51.9 39.0 42.2 40.7 43.1 41.0 38.8 46.2 39.4 43.0 19.2 12.8 4.9 42.2 53.3 83.7 101.7 8.6 17.1 67.2 85.0 88.7 84.4 47.6 46.0 4.2 172.4 29.1 303.2 219.2 113.0 38.9 40.6 39.8 47.8 104.0 40.4 4.5 118.5 187.2 38.9 28.5 33.6 30.5 75.7 39.7 223.4 167.0 23.5 6.0 257.7 44.7 62.2 34.5 127.2 39.4 36.8 58.7 1.9 59.7 29.7 45.3 3.0 4.6 126.5 126.9 32.7 24.4 137.1 196.2 258.5 35.0 17.3 32.9 30.8 65.1 46.5 56.9 30.1 60.5 112.5 25.2 126.0 364.0 109.8 MRPL14 "MRP-L32, RPML32" ENSG00000180992 "Mitochondrial ribosomal protein L14" Q6P1L8 6 44113451-44127452 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 182.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 622.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038769, HPA076790" Uncertain Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA038769: AB_10673288, HPA076790: AB_2686815" "unprognostic (4.58e-1)" "unprognostic (8.39e-2)" "unprognostic (1.84e-1)" "unprognostic (7.25e-2)" "unprognostic (1.15e-1)" "unprognostic (1.20e-2)" "unprognostic (1.19e-2)" "unprognostic (3.21e-2)" "unprognostic (7.20e-2)" "prognostic favorable (4.81e-4)" "unprognostic (1.74e-2)" "unprognostic (3.75e-1)" "prognostic unfavorable (7.46e-5)" "unprognostic (7.13e-2)" "unprognostic (1.65e-1)" "prognostic favorable (1.08e-4)" "unprognostic (3.27e-2)" 26.5 41.0 25.7 22.4 26.1 20.7 25.0 25.2 28.5 23.7 24.7 38.0 36.1 29.4 25.5 41.9 22.9 16.2 48.8 25.8 25.3 34.7 80.3 57.8 26.0 25.5 24.7 16.2 24.9 20.6 23.2 26.3 25.5 25.0 34.8 23.6 30.0 19.2 182.1 43.4 29.5 27.7 25.8 26.0 30.1 51.4 26.2 35.3 24.3 109.4 28.6 35.9 27.6 26.5 216.0 90.2 62.5 87.1 53.0 51.4 79.6 78.5 77.8 102.6 101.6 189.1 73.8 93.1 86.7 67.4 98.2 85.9 71.2 127.9 80.8 111.2 193.8 96.1 77.2 235.1 65.3 92.1 64.8 48.2 68.5 96.7 57.1 78.7 85.9 78.8 205.9 58.3 91.7 216.3 111.4 144.6 54.8 622.6 85.8 78.8 70.2 126.7 170.8 104.9 138.8 54.2 50.4 97.5 101.7 53.9 89.5 93.1 69.1 90.4 135.6 65.6 137.9 71.9 68.3 221.8 102.3 90.5 67.4 45.3 115.6 26.3 79.0 113.7 95.1 111.9 100.3 90.5 108.3 105.3 79.2 81.1 6.7 171.4 78.4 122.2 76.1 107.1 25.7 26.1 25.2 28.5 25.8 25.3 25.5 24.7 25.5 25.8 26.2 26.5 48.2 375.0 250.0 3.6 64.5 231.1 200.5 362.7 65.4 29.8 126.6 146.3 136.9 112.9 217.2 57.0 31.3 179.5 51.1 257.9 203.5 205.3 293.1 94.9 66.0 82.0 93.4 78.4 5.0 220.2 206.2 76.4 82.0 101.5 44.4 83.4 50.3 341.2 279.8 33.7 5.3 158.3 219.7 52.0 164.6 122.9 74.6 66.1 69.4 3.7 152.9 66.0 85.5 4.5 7.3 333.0 278.5 53.4 73.7 376.8 203.7 258.7 157.5 70.0 46.0 63.3 149.4 199.2 122.3 116.6 281.3 160.1 56.3 100.5 199.5 376.3 MRPL15 "HSPC145, L15mt, MRP-L15, MRP-L7, RPML7" ENSG00000137547 "Mitochondrial ribosomal protein L15" Q9P015 8 54135241-54148514 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 291.2;tongue: 279.4" "Cell type enhanced" "Detected in all" "Distal tubular cells: 248.4;Syncytiotrophoblasts: 198.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044425 Enhanced Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA044425: AB_10969629" "unprognostic (5.67e-3)" "unprognostic (8.89e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (5.37e-4)" "unprognostic (9.30e-2)" "unprognostic (1.90e-2)" "unprognostic (2.57e-2)" "unprognostic (3.10e-3)" "unprognostic (1.39e-1)" "unprognostic (3.39e-2)" "unprognostic (1.94e-3)" "unprognostic (1.57e-2)" "unprognostic (2.56e-2)" "unprognostic (1.47e-1)" "unprognostic (1.23e-1)" "unprognostic (1.06e-1)" "unprognostic (1.06e-2)" 42.5 34.4 33.2 36.4 34.1 25.1 49.3 37.0 50.5 32.6 38.7 70.8 58.6 28.6 27.7 48.8 35.6 29.0 169.6 33.5 38.3 83.8 89.2 26.5 42.9 36.6 35.7 30.5 29.2 83.4 18.6 49.6 35.8 27.5 67.5 63.1 41.4 29.0 291.2 38.5 50.6 45.4 33.8 27.3 38.4 14.7 38.3 38.1 35.2 279.4 57.4 64.1 26.3 33.0 164.1 118.9 98.0 122.6 76.1 110.5 125.8 128.4 93.0 173.3 150.2 134.1 197.1 253.9 170.3 112.1 164.4 161.5 206.2 165.5 190.4 109.9 109.5 165.8 62.4 168.5 114.5 92.0 168.9 103.3 167.4 159.5 165.6 74.7 366.7 89.4 208.2 80.8 251.3 156.1 262.4 177.3 206.2 313.9 60.8 169.5 63.6 136.3 210.8 147.1 56.5 83.7 66.8 204.0 167.0 97.4 195.2 96.6 129.6 95.8 111.7 139.5 151.5 94.6 128.4 207.1 88.8 137.8 153.4 40.1 93.8 27.3 50.7 123.4 63.8 100.6 64.8 68.4 141.1 76.6 59.0 56.9 3.3 54.0 115.7 88.9 79.8 85.8 33.2 34.1 37.0 50.5 33.5 38.3 36.6 35.7 35.8 33.8 38.3 33.0 28.0 25.6 14.4 9.4 33.1 23.6 40.7 114.5 19.4 28.2 25.0 37.2 120.9 55.8 50.4 36.8 29.2 160.3 17.6 38.7 248.4 103.2 18.7 34.0 34.4 34.8 18.0 31.7 10.9 70.9 155.2 32.8 23.9 39.2 25.4 37.9 26.4 59.2 106.1 25.2 12.4 52.5 75.3 44.5 22.9 4.3 24.8 37.9 33.8 7.5 56.5 37.4 20.6 11.1 6.0 97.5 34.3 22.6 35.3 33.9 66.8 127.0 32.1 58.8 13.1 32.1 70.1 14.8 34.3 37.3 34.4 198.9 19.7 91.3 78.3 41.8 MRPL19 "KIAA0104, MRP-L15, RLX1, RPML15" ENSG00000115364 "Mitochondrial ribosomal protein L19" P49406 2 75646783-75690851 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 167.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046805, HPA056622" Approved Supported Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 8: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA046805: AB_2679816, HPA056622: AB_2683195" "unprognostic (9.24e-2)" "unprognostic (3.84e-2)" "prognostic favorable (7.39e-4)" "unprognostic (8.40e-2)" "unprognostic (1.59e-2)" "unprognostic (7.52e-3)" "unprognostic (5.75e-2)" "unprognostic (9.86e-2)" "unprognostic (6.21e-3)" "unprognostic (9.71e-3)" "prognostic unfavorable (1.97e-5)" "unprognostic (2.42e-1)" "unprognostic (3.67e-2)" "unprognostic (1.55e-1)" "unprognostic (3.30e-1)" "unprognostic (1.12e-1)" "unprognostic (1.20e-1)" 31.3 30.1 21.8 18.9 27.4 13.9 28.6 26.5 23.5 29.1 14.8 27.8 23.7 21.7 25.2 25.0 18.1 20.7 35.0 18.8 26.7 56.0 63.7 17.8 20.3 23.4 24.4 17.4 23.6 45.2 12.2 25.7 25.4 21.6 30.9 19.3 24.1 25.1 66.4 23.9 19.9 29.0 26.8 16.9 18.4 16.5 24.9 24.3 36.9 44.8 25.1 24.5 15.1 32.5 100.7 57.5 53.3 48.3 57.0 68.1 75.6 63.4 57.0 78.5 62.2 88.5 40.6 56.5 62.1 69.2 73.8 69.5 83.7 95.8 117.8 63.2 72.4 77.4 44.4 114.3 61.0 82.9 44.5 45.6 72.4 79.7 72.3 49.6 84.1 60.8 86.4 32.3 78.5 61.9 76.1 64.9 69.9 102.9 65.2 94.5 116.5 74.5 134.1 61.9 58.8 50.2 62.2 71.2 72.4 53.3 61.1 32.8 57.0 68.3 75.4 61.2 94.6 33.3 53.8 47.1 53.9 81.0 61.1 17.7 20.2 14.2 22.1 26.8 25.1 26.8 22.7 23.8 29.7 22.7 19.9 24.6 1.4 24.4 24.9 35.0 26.5 17.2 21.8 27.4 26.5 23.5 18.8 26.7 23.4 24.4 25.4 26.8 24.9 32.5 31.8 19.2 29.6 10.7 27.4 29.1 28.6 77.8 21.1 38.3 32.4 29.5 40.2 25.8 49.4 49.7 52.1 90.3 26.3 24.0 125.2 88.7 27.6 42.7 48.4 27.7 27.6 32.8 13.9 61.1 87.3 33.7 36.7 50.3 19.0 35.8 27.1 67.6 47.3 48.8 14.3 36.5 44.7 14.6 17.0 11.2 35.4 23.7 33.8 12.2 35.0 39.6 34.0 15.1 20.0 53.6 27.7 36.5 36.5 36.1 36.5 167.7 32.8 50.9 19.7 31.4 38.1 55.5 17.6 44.3 28.3 57.7 25.3 62.2 50.7 35.6 MRPL20 FLJ10024 ENSG00000242485 "Mitochondrial ribosomal protein L20" Q9BYC9 1 1401909-1407293 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047074 Supported Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA047074: AB_10964064" "unprognostic (4.04e-2)" "unprognostic (1.06e-1)" "unprognostic (3.55e-2)" "unprognostic (5.79e-2)" "unprognostic (3.71e-1)" "unprognostic (2.66e-1)" "unprognostic (1.07e-1)" "unprognostic (2.35e-1)" "unprognostic (1.03e-1)" "unprognostic (1.78e-2)" "unprognostic (2.80e-2)" "unprognostic (2.33e-1)" "unprognostic (4.18e-2)" "unprognostic (1.25e-1)" "unprognostic (1.25e-1)" "unprognostic (4.34e-2)" "unprognostic (1.64e-1)" 111.5 120.2 144.2 81.8 156.1 72.1 110.0 144.3 178.5 86.5 148.7 126.7 83.6 89.7 135.0 117.2 90.2 68.5 189.8 146.7 154.3 140.9 152.7 86.7 100.4 152.4 154.1 84.2 136.6 100.6 117.3 68.6 147.2 110.9 86.9 59.6 131.9 90.3 277.2 97.7 91.3 75.4 158.1 100.2 116.8 60.5 168.6 71.8 102.3 160.9 102.5 107.6 87.6 158.1 216.1 204.2 149.7 152.8 113.4 122.7 110.6 188.3 143.8 240.7 171.1 244.9 255.4 228.5 256.8 162.9 111.4 133.8 247.6 203.8 185.9 199.0 350.3 247.0 369.0 244.8 156.5 367.3 152.7 143.9 76.8 184.8 196.4 138.4 181.1 213.8 254.6 131.8 204.8 216.3 285.2 279.2 155.8 249.6 409.1 186.0 138.3 291.3 189.9 142.8 265.4 218.5 179.2 369.9 288.7 124.7 158.8 268.0 155.2 144.9 170.0 219.6 236.2 200.6 313.5 450.5 224.2 296.4 103.7 124.6 191.2 146.5 164.8 190.1 183.7 189.3 181.9 163.3 198.2 177.2 204.1 199.0 89.2 163.1 150.8 289.2 175.0 219.6 144.2 156.1 144.3 178.5 146.7 154.3 152.4 154.1 147.2 158.1 168.6 158.1 97.5 67.3 115.5 19.9 120.3 130.3 134.8 206.8 99.0 77.8 153.0 171.4 255.2 145.8 166.0 161.8 35.5 234.5 129.2 138.6 530.2 232.6 39.3 153.1 121.8 118.4 138.2 152.7 13.7 325.9 265.0 113.6 87.7 126.3 106.2 92.7 131.0 384.0 220.6 50.5 13.8 185.5 177.0 139.7 111.0 30.7 107.8 117.9 138.7 11.2 200.8 279.3 183.4 9.5 20.8 261.8 167.4 110.9 163.3 254.8 194.1 543.9 146.9 107.7 65.7 121.8 135.7 131.7 202.7 179.9 157.7 226.2 109.2 121.9 216.1 170.2 MRPL22 "HSPC158, MRP-L25, RPML25" ENSG00000082515 "Mitochondrial ribosomal protein L22" Q9NWU5 5 154941073-154969411 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047063 Uncertain Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA047063: AB_2679919" "unprognostic (9.17e-2)" "unprognostic (1.18e-2)" "unprognostic (2.16e-2)" "unprognostic (2.56e-2)" "unprognostic (5.42e-2)" "unprognostic (6.65e-2)" "unprognostic (1.80e-2)" "unprognostic (4.86e-2)" "unprognostic (2.03e-1)" "unprognostic (3.01e-3)" "unprognostic (3.40e-1)" "unprognostic (1.14e-1)" "unprognostic (1.77e-1)" "unprognostic (3.54e-1)" "unprognostic (2.69e-1)" "unprognostic (4.09e-2)" "unprognostic (4.29e-2)" 23.9 38.4 18.4 20.3 18.4 40.9 26.3 20.0 27.9 20.7 17.7 28.4 26.1 20.5 26.0 30.8 18.9 15.4 46.3 18.5 19.0 37.5 49.3 19.6 28.5 19.5 18.8 18.1 30.3 31.2 23.8 24.2 19.7 19.4 28.0 17.0 24.8 19.3 38.5 23.6 22.9 20.0 18.7 26.2 27.1 29.4 18.8 28.2 23.3 34.5 27.1 24.6 21.6 19.6 68.5 65.8 57.1 79.7 43.7 55.0 67.9 47.6 55.9 93.9 118.3 191.5 82.8 93.7 82.9 40.1 100.0 61.2 83.2 90.0 99.8 32.2 94.3 36.1 64.1 110.1 57.1 81.5 47.2 36.5 59.4 63.4 76.9 41.8 161.8 84.6 55.2 81.9 58.8 100.8 74.1 78.3 43.5 74.0 50.6 67.4 49.6 97.9 93.1 50.9 65.4 24.3 62.5 89.1 104.9 41.0 130.2 71.3 47.5 57.7 57.5 51.1 89.3 43.4 57.5 104.4 57.9 99.7 55.4 35.9 49.0 44.1 47.5 59.7 48.7 72.3 51.5 51.3 66.6 61.5 47.7 54.6 19.8 64.0 60.4 51.9 75.1 62.4 18.4 18.4 20.0 27.9 18.5 19.0 19.5 18.8 19.7 18.7 18.8 19.6 55.2 25.6 28.1 11.1 52.2 63.9 54.4 191.6 43.9 28.1 45.9 67.9 213.2 64.3 95.6 60.7 27.1 144.6 37.9 46.6 223.0 114.9 56.2 49.6 44.4 69.2 49.6 64.0 13.0 127.1 132.6 64.7 27.0 41.3 45.0 56.2 51.4 85.2 99.3 32.0 11.8 65.6 79.3 33.2 57.1 29.3 66.2 35.7 51.6 2.8 61.3 35.9 56.7 11.1 20.1 113.9 83.4 75.2 71.1 47.2 68.1 203.7 89.0 27.1 32.9 48.5 86.7 167.7 67.0 50.3 65.8 78.5 48.4 122.2 78.5 54.6 MRPL28 "MAAT1, p15" ENSG00000086504 "Mitochondrial ribosomal protein L28" Q13084 16 366969-371289 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030594, CAB033542, HPA055589" Supported Supported Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "CAB033542: AB_2145899, HPA030594: AB_10601136, HPA055589: AB_2682855" "unprognostic (2.39e-1)" "unprognostic (7.39e-3)" "unprognostic (1.53e-1)" "unprognostic (1.26e-1)" "unprognostic (2.15e-2)" "unprognostic (9.92e-2)" "unprognostic (2.92e-1)" "unprognostic (3.45e-3)" "unprognostic (6.76e-2)" "unprognostic (1.73e-1)" "unprognostic (7.69e-2)" "unprognostic (1.71e-1)" "unprognostic (2.62e-2)" "unprognostic (2.43e-1)" "unprognostic (4.36e-1)" "unprognostic (2.60e-1)" "unprognostic (6.56e-2)" 43.3 63.2 43.2 25.8 46.6 43.7 43.6 41.6 55.9 40.8 39.9 48.9 31.4 47.0 20.6 58.0 39.4 23.3 101.0 46.9 42.7 74.9 79.9 38.7 30.4 41.2 41.7 36.4 32.2 46.6 44.0 21.1 42.5 45.3 18.1 20.4 37.9 23.8 87.6 45.9 43.0 25.8 41.2 52.2 43.8 85.2 42.2 36.8 44.2 59.3 27.1 43.1 42.3 43.9 72.8 135.8 68.3 82.9 37.9 48.6 90.1 82.6 107.3 147.2 143.2 175.4 95.9 105.5 88.6 85.0 75.3 87.6 107.8 172.6 78.2 95.4 211.8 78.7 110.0 149.2 123.9 98.1 96.1 73.8 84.6 136.3 110.5 69.0 109.5 99.5 143.8 75.6 93.0 249.0 152.9 98.2 109.1 72.3 82.5 181.7 85.2 149.1 121.4 41.3 115.2 102.4 102.5 100.3 84.6 66.4 131.1 92.4 85.5 86.0 118.6 70.8 92.4 111.1 100.3 143.0 60.0 68.4 140.8 95.4 105.7 122.1 71.0 107.2 59.1 93.3 62.0 68.9 96.6 105.0 43.0 54.7 120.5 79.3 115.1 119.0 125.8 97.9 43.2 46.6 41.6 55.9 46.9 42.7 41.2 41.7 42.5 41.2 42.2 43.9 44.2 38.5 34.1 8.5 43.6 34.7 50.4 134.5 25.6 34.8 35.6 36.4 55.4 40.0 69.0 69.9 8.4 87.0 46.8 70.2 193.7 112.5 97.7 35.3 30.0 44.9 64.1 51.3 5.8 111.9 108.0 41.2 37.2 31.2 26.6 57.2 47.2 66.6 99.7 28.6 5.0 54.6 77.3 66.5 36.1 232.6 38.2 47.8 71.2 2.8 136.1 56.1 45.3 3.0 5.4 107.0 76.5 38.4 47.2 46.7 106.3 180.0 55.4 42.5 39.5 31.0 61.9 122.2 50.5 38.9 32.4 45.8 37.1 86.6 65.8 52.9 MRPL37 "MRP-L2, RPML2" ENSG00000116221 "Mitochondrial ribosomal protein L37" Q9BZE1 1 54184041-54225464 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025767, HPA025826, HPA025951" Supported Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Mitochondria "HPA025767: AB_1854105, HPA025826: AB_1854106, HPA025951: AB_1854107" "unprognostic (2.00e-1)" "unprognostic (6.81e-2)" "prognostic favorable (6.99e-4)" "unprognostic (1.71e-3)" "unprognostic (8.24e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (6.45e-5)" "unprognostic (2.49e-2)" "unprognostic (1.56e-1)" "unprognostic (1.64e-1)" "unprognostic (1.92e-2)" "unprognostic (1.84e-1)" "unprognostic (3.07e-1)" "prognostic favorable (9.25e-4)" "unprognostic (2.43e-1)" "unprognostic (2.62e-1)" "unprognostic (7.67e-3)" 44.7 73.8 28.6 32.4 30.6 67.4 41.5 35.5 37.2 36.1 42.7 50.7 51.5 34.7 26.9 65.8 38.2 25.5 86.3 31.5 29.8 55.4 108.1 30.2 41.1 32.5 30.3 41.0 67.7 47.2 20.8 31.5 33.2 33.8 53.5 21.8 41.3 29.8 167.9 56.2 41.0 41.6 27.4 34.6 49.2 31.4 30.8 41.2 28.5 154.2 51.3 37.9 40.5 28.7 168.3 94.9 84.6 114.5 83.4 110.9 150.5 111.2 103.5 194.0 167.7 190.7 75.4 226.1 98.2 125.3 184.8 131.6 168.2 164.6 150.6 111.1 211.7 194.8 186.9 194.8 142.9 233.3 87.1 123.2 138.7 201.8 156.5 108.7 176.1 174.2 219.2 66.1 140.2 123.3 161.7 226.4 173.5 134.4 208.2 175.3 171.7 191.6 110.8 123.4 166.3 77.6 153.8 261.4 214.0 110.6 113.2 260.7 88.5 123.6 112.2 157.7 227.1 83.1 126.0 175.5 161.1 234.2 119.9 53.0 103.4 45.4 67.5 91.8 79.1 120.4 81.9 76.1 120.4 105.1 82.0 72.8 5.6 94.0 88.7 101.5 116.4 126.6 28.6 30.6 35.5 37.2 31.5 29.8 32.5 30.3 33.2 27.4 30.8 28.7 24.0 22.4 18.7 3.9 33.4 34.7 43.8 84.6 45.5 8.9 46.3 57.0 71.3 55.8 43.1 18.4 2.1 118.0 15.5 36.6 80.3 81.2 31.0 25.7 23.2 30.3 33.1 103.3 7.5 96.3 145.8 37.3 41.8 33.1 14.5 40.6 37.5 156.5 87.0 6.7 8.4 53.0 52.9 43.6 25.6 57.5 26.1 30.9 23.2 4.7 53.1 9.2 24.7 4.5 5.4 69.0 41.1 28.6 72.2 54.2 73.8 105.2 29.4 8.7 13.1 28.8 34.3 23.6 50.4 79.6 37.4 73.9 24.5 57.2 86.0 55.2 MRPL38 "HSPC262, MGC4810, MRP-L3, RPML3" ENSG00000204316 "Mitochondrial ribosomal protein L38" Q96DV4 17 75898644-75905093 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 34.7;Gastric mucus-secreting cells: 35.2;Plasma cells: 60.1;Squamous epithelial cells: 46.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023054, HPA023135" Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA023054: AB_1854109, HPA023135: AB_1854110" "unprognostic (1.17e-1)" "unprognostic (3.77e-3)" "unprognostic (1.83e-1)" "unprognostic (3.68e-3)" "unprognostic (2.47e-2)" "unprognostic (1.50e-2)" "unprognostic (4.44e-2)" "unprognostic (1.61e-1)" "unprognostic (7.59e-2)" "unprognostic (5.24e-2)" "prognostic favorable (4.23e-4)" "unprognostic (2.16e-3)" "prognostic unfavorable (5.58e-4)" "unprognostic (3.06e-2)" "unprognostic (2.40e-1)" "unprognostic (3.72e-1)" "prognostic favorable (9.21e-5)" 23.3 34.7 37.5 16.3 37.4 21.9 22.8 39.7 48.9 20.2 37.8 31.1 26.8 24.0 14.4 30.0 30.6 14.6 51.5 37.7 38.2 31.3 46.8 18.2 23.8 39.4 37.6 22.3 36.8 28.7 19.6 17.3 39.8 22.6 19.2 6.7 36.6 26.2 103.2 26.9 21.9 20.3 38.1 22.5 28.6 25.3 40.4 23.8 20.6 84.7 22.4 25.9 21.0 38.6 82.2 114.2 28.3 39.2 32.5 26.5 86.5 26.4 44.5 96.3 69.5 134.4 49.3 72.7 31.2 45.9 55.1 59.1 79.2 71.1 27.3 24.0 130.5 51.0 39.9 133.7 72.0 69.5 48.6 36.6 77.3 66.8 52.4 29.3 92.6 89.7 64.6 45.6 36.6 163.0 92.9 75.1 33.6 101.8 97.2 69.1 74.7 92.3 76.3 51.0 48.6 51.4 45.3 121.3 104.5 26.1 112.4 74.4 26.3 45.8 67.2 38.6 75.4 51.1 32.1 24.7 50.0 57.1 41.3 24.4 74.1 37.9 84.2 80.8 84.0 101.8 86.0 79.1 106.7 113.7 84.8 81.7 7.0 95.7 69.1 78.1 93.7 83.6 37.5 37.4 39.7 48.9 37.7 38.2 39.4 37.6 39.8 38.1 40.4 38.6 1.7 19.2 7.3 14.7 19.3 1.5 0.8 2.7 34.7 1.0 2.4 1.1 2.3 0.0 5.5 3.7 0.0 5.1 6.6 11.4 3.9 23.8 1.1 2.2 1.8 4.7 10.3 20.2 11.9 21.4 3.7 8.1 35.2 1.8 3.8 1.0 2.5 2.4 3.3 1.7 13.2 13.9 2.0 0.8 1.9 1.9 3.1 6.1 7.2 5.6 14.2 0.9 5.2 7.5 15.7 19.2 17.9 3.0 60.1 1.3 16.3 5.6 9.8 2.9 0.0 0.9 8.3 1.9 1.9 46.2 1.4 3.4 13.6 1.2 20.9 0.8 MRPL39 "C21orf92, FLJ20451, L39mt, MGC104174, MGC3400, MRP-L5, MSTP003, PRED22, PRED66, RPML5" ENSG00000154719 "Mitochondrial ribosomal protein L39" Q9NYK5 21 25585656-25607517 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 241.5;Spermatocytes: 103.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018331 Approved Supported Mitochondria NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "HPA018331: AB_1854111" "unprognostic (3.81e-3)" "unprognostic (5.34e-2)" "unprognostic (8.55e-3)" "unprognostic (4.61e-1)" "unprognostic (2.61e-1)" "unprognostic (4.32e-2)" "unprognostic (6.75e-2)" "unprognostic (2.35e-1)" "unprognostic (4.74e-2)" "unprognostic (1.94e-1)" "prognostic unfavorable (5.84e-4)" "unprognostic (7.48e-2)" "unprognostic (7.32e-3)" "unprognostic (9.81e-2)" "unprognostic (1.66e-1)" "unprognostic (2.45e-2)" "unprognostic (6.89e-2)" 23.1 35.6 18.2 19.7 19.6 22.7 26.7 22.1 28.7 16.7 18.4 29.2 25.5 18.0 41.7 26.5 20.4 13.5 51.4 18.3 19.2 40.4 55.3 15.3 34.2 18.7 18.1 17.6 25.2 71.0 13.4 26.2 19.8 20.0 32.1 21.5 21.8 17.8 58.6 20.3 23.1 22.0 19.0 17.6 22.9 54.7 18.2 24.9 20.1 56.7 37.3 22.3 18.8 21.6 89.6 43.0 60.1 38.1 29.7 42.9 92.3 56.1 50.0 77.0 64.7 85.2 49.2 97.9 30.9 35.4 69.8 25.5 128.5 76.4 85.9 49.1 66.3 100.1 43.0 91.4 34.6 102.4 31.7 34.8 66.7 76.3 62.2 42.7 58.2 99.6 112.3 78.4 77.1 56.0 67.5 55.5 95.6 88.9 65.4 77.8 97.0 103.1 80.6 35.7 37.9 36.3 51.6 94.5 76.3 42.3 68.3 57.6 36.4 40.8 61.0 43.9 69.6 54.9 74.6 121.9 61.2 109.1 62.5 41.9 16.9 20.7 37.0 30.3 46.9 62.0 45.0 42.3 31.0 49.1 43.9 39.3 2.8 36.7 21.6 43.2 56.4 18.6 18.2 19.6 22.1 28.7 18.3 19.2 18.7 18.1 19.8 19.0 18.2 21.6 18.3 25.6 10.5 9.8 17.6 20.0 20.3 71.0 7.4 20.4 14.0 23.5 78.2 10.0 36.2 25.8 10.4 46.8 14.1 8.7 31.3 36.0 241.5 20.9 12.7 22.2 7.8 22.3 11.4 33.8 41.7 19.4 7.1 11.8 15.2 11.3 18.9 19.8 30.8 10.1 11.7 11.4 30.5 10.6 15.7 37.0 14.9 11.3 19.6 9.4 17.1 19.0 11.3 9.5 13.2 26.5 9.3 23.3 13.6 13.2 20.4 46.8 41.8 15.0 46.0 18.1 25.4 103.0 29.4 10.7 16.9 36.9 14.9 25.7 20.1 17.3 MRPL41 "BMRP, MRP-L27, MRPL27, PIG3, RPML27" ENSG00000182154 "Mitochondrial ribosomal protein L41" Q8IXM3 9 137551879-137552555 "Predicted intracellular proteins, Ribosomal proteins" "Apoptosis, Cell cycle" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 340.5;skeletal muscle: 407.5" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 909.5;Distal tubular cells: 972.4;Hepatocytes: 856.2;Late spermatids: 839.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 503.2;PC-3: 471.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024550, HPA027160" Supported Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA024550: AB_1854112, HPA027160: AB_1854113" "unprognostic (3.92e-1)" "unprognostic (1.61e-2)" "unprognostic (6.92e-2)" "unprognostic (1.22e-3)" "unprognostic (5.86e-3)" "unprognostic (8.04e-2)" "unprognostic (2.05e-1)" "unprognostic (1.60e-1)" "unprognostic (1.47e-1)" "unprognostic (1.14e-1)" "unprognostic (4.83e-3)" "unprognostic (3.24e-2)" "unprognostic (2.06e-3)" "unprognostic (3.28e-2)" "unprognostic (1.01e-1)" "unprognostic (2.43e-1)" "unprognostic (3.32e-2)" 83.7 74.7 222.0 22.9 206.1 26.1 57.4 203.8 340.5 53.9 169.2 66.4 45.4 45.9 8.4 42.4 46.6 14.8 325.4 210.3 190.6 79.8 157.8 42.1 24.6 209.0 190.7 61.1 44.8 42.2 55.1 12.2 187.9 113.0 17.4 9.9 69.6 26.2 407.5 58.6 56.8 12.2 183.4 54.2 79.1 40.3 227.1 16.1 44.9 129.4 13.1 59.4 45.4 188.9 93.7 165.9 25.5 61.9 40.7 35.5 122.1 112.8 33.1 59.1 47.4 122.6 49.6 71.0 148.4 31.5 78.0 186.5 37.4 60.0 6.4 97.9 208.6 62.0 91.9 193.6 92.8 101.1 211.4 67.3 85.4 51.5 18.2 23.4 55.4 58.7 147.8 26.8 32.6 503.2 33.7 337.6 94.6 118.0 471.6 40.1 44.0 95.9 50.5 67.7 85.7 88.6 78.0 138.6 194.5 15.2 124.0 91.5 95.4 93.1 121.3 162.9 153.4 78.4 146.2 133.7 101.8 104.4 70.9 425.2 305.5 251.8 225.6 272.9 211.5 313.8 235.0 257.0 260.3 249.7 221.0 206.2 38.3 180.8 254.2 422.6 332.2 350.3 222.0 206.1 203.8 340.5 210.3 190.6 209.0 190.7 187.9 183.4 227.1 188.9 99.0 28.9 33.6 59.7 90.7 140.1 138.3 239.3 121.3 52.4 193.9 221.5 909.5 178.7 121.1 263.0 10.4 115.9 89.7 670.5 972.4 157.8 299.6 165.2 136.0 103.1 268.5 66.0 30.6 192.1 147.7 127.1 192.7 136.7 54.0 85.4 102.1 856.2 244.8 28.6 47.7 332.9 229.9 122.7 115.4 839.0 121.8 106.0 224.1 15.9 162.1 102.7 95.8 8.0 31.1 222.8 446.5 104.6 146.9 223.1 458.4 657.6 134.9 47.5 111.7 66.8 143.8 112.6 79.7 175.6 166.1 82.2 112.8 249.9 348.8 176.8 MRPL45 MGC11321 ENSG00000278845 "Mitochondrial ribosomal protein L45" 17 38297023-38323217 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebral cortex: 8.4" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "AF22: 35.7;Daudi: 80.9;K-562: 57.0;REH: 43.2;RPMI-8226: 34.4;RT4: 33.9;U-266/84: 52.1;U-698: 56.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023373, HPA023385" Enhanced Enhanced Mitochondria NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 32: Non-specific - Translation" Mitochondria "HPA023373: AB_1854114, HPA023385: AB_1854115" "unprognostic (8.56e-3)" "unprognostic (4.09e-2)" "unprognostic (1.11e-2)" "unprognostic (3.08e-1)" "unprognostic (9.50e-2)" "unprognostic (2.22e-3)" "unprognostic (1.11e-2)" "unprognostic (1.60e-1)" "unprognostic (7.21e-2)" "unprognostic (1.37e-2)" "unprognostic (3.65e-1)" "unprognostic (1.35e-1)" "unprognostic (6.01e-3)" "unprognostic (3.07e-1)" "unprognostic (1.00e-1)" "unprognostic (2.40e-1)" "unprognostic (8.13e-2)" 24.0 26.7 1.5 2.2 1.9 1.9 24.1 1.6 8.4 21.1 2.2 24.6 0.0 21.4 0.0 25.3 19.8 4.0 32.1 1.6 1.6 26.0 30.7 15.2 8.0 1.7 1.6 28.3 36.8 9.0 13.1 1.7 1.7 18.0 5.7 1.3 22.4 0.0 61.8 26.5 19.6 0.7 1.5 16.3 30.0 9.5 1.6 2.6 18.2 0.0 6.9 22.1 20.1 1.6 0.0 0.5 35.7 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 26.8 80.9 0.2 0.0 24.2 0.5 0.2 0.0 0.1 0.0 0.3 31.1 0.0 2.1 12.7 0.0 0.2 0.0 0.3 0.1 0.0 0.1 0.0 0.0 57.0 0.0 0.2 0.0 23.1 0.0 0.3 0.1 0.0 43.2 0.2 34.4 0.0 33.9 0.1 0.2 0.2 0.6 0.2 0.1 0.1 0.2 0.5 15.1 0.1 0.0 0.3 23.2 52.1 56.9 0.1 0.0 0.4 0.6 6.7 2.2 5.3 8.2 6.4 7.6 7.7 4.1 11.3 6.8 9.8 6.6 0.2 9.8 2.3 4.8 6.6 6.3 1.5 1.9 1.6 8.4 1.6 1.6 1.7 1.6 1.7 1.5 1.6 1.6 20.4 12.8 12.1 6.8 23.8 30.2 39.3 54.6 42.7 10.9 41.3 37.7 46.5 32.9 23.9 25.8 8.4 69.3 16.3 11.3 60.7 41.5 18.3 21.6 25.6 26.9 16.3 45.9 10.4 37.5 67.7 25.1 24.5 21.1 23.5 31.4 22.5 30.4 42.6 16.8 12.0 27.4 34.6 39.1 21.1 15.0 20.8 22.2 19.6 1.9 43.8 13.0 22.6 7.5 9.2 29.6 15.5 16.6 23.7 28.8 32.0 64.0 21.6 11.1 6.6 28.4 25.2 30.6 18.0 31.9 32.4 71.1 19.3 42.6 41.8 33.3 MRPL47 "CGI-204, NCM1" ENSG00000136522 "Mitochondrial ribosomal protein L47" Q9HD33 3 179588285-179604649 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 399.7;Spermatocytes: 301.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037553, HPA047779" Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "HPA037553: AB_10671375, HPA047779: AB_2680154" "unprognostic (6.37e-2)" "prognostic favorable (6.44e-4)" "unprognostic (7.21e-2)" "prognostic unfavorable (3.15e-4)" "unprognostic (1.53e-1)" "unprognostic (8.55e-3)" "unprognostic (1.16e-2)" "unprognostic (1.82e-2)" "unprognostic (1.58e-1)" "unprognostic (8.03e-3)" "unprognostic (1.70e-2)" "unprognostic (1.29e-2)" "unprognostic (5.64e-2)" "unprognostic (3.06e-1)" "unprognostic (1.75e-1)" "unprognostic (1.71e-1)" "unprognostic (8.84e-2)" 27.2 34.8 30.6 24.0 31.7 48.8 27.2 34.2 41.1 19.4 34.2 32.1 23.7 23.0 22.8 31.8 18.9 18.5 54.9 29.4 34.7 44.4 35.5 20.1 30.0 32.0 31.8 16.6 17.4 33.9 24.0 22.2 32.6 20.6 31.8 26.6 21.1 18.9 52.5 21.5 22.6 24.7 33.3 24.3 26.2 53.1 32.6 33.3 21.0 56.9 30.4 32.0 21.7 34.2 128.6 48.6 83.0 76.7 51.5 53.5 95.2 73.2 65.1 112.3 93.2 198.6 51.8 104.7 140.6 62.5 137.2 94.5 103.5 76.9 120.5 121.0 90.9 99.8 46.1 112.5 99.8 182.2 54.2 49.6 65.7 83.4 84.7 53.1 77.2 95.9 59.5 81.4 88.1 98.9 98.4 168.4 144.3 115.4 114.6 102.7 81.1 175.3 120.4 79.6 71.8 83.5 80.7 128.6 151.2 61.9 198.6 136.6 61.6 60.7 87.4 77.1 204.5 102.1 182.4 229.3 70.7 147.4 75.8 38.2 32.4 44.2 31.7 43.8 32.2 35.1 35.1 34.7 48.4 31.8 30.4 31.7 8.5 41.5 54.4 41.9 48.9 35.8 30.6 31.7 34.2 41.1 29.4 34.7 32.0 31.8 32.6 33.3 32.6 34.2 45.3 22.4 21.7 5.5 51.4 74.9 82.0 179.7 38.7 20.2 36.4 33.4 89.7 54.3 78.6 57.0 10.4 100.0 61.2 46.3 258.2 112.3 399.7 72.8 56.0 55.5 54.9 62.9 7.1 115.9 109.6 51.8 36.2 50.0 56.4 34.0 44.3 62.5 99.3 10.1 9.2 52.8 105.8 42.4 55.7 95.4 42.9 53.5 48.0 4.7 80.3 43.4 39.1 7.1 12.4 118.7 53.6 49.2 54.6 72.6 45.2 201.7 85.5 26.0 59.2 57.9 68.2 301.2 54.0 52.2 70.5 104.1 57.8 102.3 71.9 83.8 MRPL48 CGI-118 ENSG00000175581 "Mitochondrial ribosomal protein L48" Q96GC5 11 73787872-73865133 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 156.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040241, HPA040864" Approved Supported Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA040241: AB_2676899, HPA040864: AB_2677175" "unprognostic (2.41e-1)" "unprognostic (1.80e-2)" "unprognostic (1.56e-2)" "unprognostic (1.18e-3)" "unprognostic (1.99e-1)" "unprognostic (2.90e-2)" "prognostic unfavorable (3.30e-4)" "unprognostic (8.89e-2)" "unprognostic (4.41e-2)" "unprognostic (3.97e-2)" "unprognostic (1.14e-1)" "unprognostic (5.85e-2)" "unprognostic (4.61e-3)" "unprognostic (1.25e-1)" "unprognostic (1.48e-1)" "unprognostic (1.23e-2)" "unprognostic (3.30e-1)" 10.8 17.4 30.3 10.2 33.8 12.1 13.3 33.6 50.0 16.8 31.1 17.5 14.1 12.3 14.8 16.6 13.6 5.6 22.5 30.0 31.9 24.2 21.2 10.2 12.8 35.5 32.3 14.2 19.3 21.2 10.9 10.6 36.5 14.6 15.8 11.5 13.9 10.0 28.6 12.5 14.8 8.1 31.6 14.5 15.1 5.8 31.9 23.2 14.1 26.9 14.4 12.3 14.6 41.5 29.6 33.2 36.7 20.8 20.9 16.8 16.2 18.0 20.3 27.9 23.0 63.9 26.6 71.0 35.7 25.6 18.7 35.6 37.3 37.7 24.6 28.3 40.9 36.3 33.3 45.4 24.5 61.5 24.9 14.1 41.0 23.8 33.0 24.5 39.1 40.5 46.9 37.7 28.1 47.1 72.9 58.9 27.5 95.5 35.0 32.1 43.8 81.3 31.0 35.3 28.9 28.0 14.2 48.8 156.9 17.0 31.4 38.5 13.6 21.6 27.9 15.3 24.2 18.1 39.3 103.1 9.5 39.8 18.0 40.7 23.6 12.5 25.8 30.4 27.3 27.5 30.1 31.6 33.6 29.8 32.3 31.3 4.1 28.1 28.1 37.6 35.3 29.5 30.3 33.8 33.6 50.0 30.0 31.9 35.5 32.3 36.5 31.6 31.9 41.5 17.3 9.6 20.5 11.1 29.4 19.2 35.3 66.7 25.6 10.2 28.5 35.1 33.0 21.5 33.9 25.8 4.2 92.0 27.6 28.3 88.0 37.1 6.3 31.0 21.0 18.9 24.1 36.6 16.1 39.7 73.5 22.5 19.9 22.9 21.0 32.5 16.4 28.0 42.9 15.2 22.6 38.0 42.7 25.4 19.4 16.5 18.3 20.5 44.4 3.7 29.4 16.6 22.6 24.6 45.2 30.9 36.1 18.0 30.0 22.0 63.4 76.5 39.1 8.5 0.0 22.5 29.7 18.6 26.3 38.2 19.7 59.8 26.8 26.6 49.1 37.1 MRPL51 "bMRP64, CDA09, HSPC241, MRP64" ENSG00000111639 "Mitochondrial ribosomal protein L51" Q4U2R6 12 6491886-6493841 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 950.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039923 Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 5: NTERA-2 - Transcription" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA039923: AB_10795373" "unprognostic (1.31e-1)" "unprognostic (1.05e-1)" "unprognostic (2.97e-1)" "unprognostic (1.44e-2)" "unprognostic (1.75e-1)" "unprognostic (2.87e-1)" "unprognostic (3.81e-3)" "unprognostic (4.95e-2)" "unprognostic (1.01e-1)" "unprognostic (1.18e-2)" "unprognostic (1.43e-1)" "unprognostic (3.06e-1)" "unprognostic (1.50e-1)" "unprognostic (3.36e-1)" "unprognostic (2.62e-1)" "unprognostic (1.17e-1)" "unprognostic (8.33e-2)" 95.7 128.2 151.3 77.1 158.1 88.1 83.2 161.6 239.9 88.4 151.8 119.2 65.5 80.2 99.3 146.1 82.4 49.4 252.5 151.0 159.2 157.9 158.5 75.9 104.5 158.5 155.3 78.9 119.7 128.2 109.3 70.0 158.6 105.8 91.5 64.4 87.0 63.7 262.7 93.2 85.9 70.9 157.3 99.6 112.3 233.3 156.2 131.4 90.6 240.5 126.7 104.2 90.7 165.5 263.4 286.8 334.5 244.1 235.8 212.8 390.6 187.7 222.5 277.1 258.1 398.4 325.4 376.3 124.4 278.2 330.2 220.8 272.4 298.1 409.8 456.3 294.7 256.3 415.2 340.8 217.7 352.4 206.2 205.7 237.2 251.1 331.4 357.9 265.4 291.0 186.1 114.0 356.2 374.3 356.7 463.3 707.1 471.1 287.1 248.2 384.5 264.8 232.6 319.7 126.4 222.2 320.9 355.8 305.4 662.7 107.6 323.7 218.1 226.0 318.5 188.8 406.3 109.0 177.7 850.0 279.8 243.3 305.6 224.5 202.0 231.8 181.6 196.4 206.8 229.3 193.2 201.4 234.6 211.9 196.4 201.4 77.5 203.3 197.8 318.4 234.4 294.0 151.3 158.1 161.6 239.9 151.0 159.2 158.5 155.3 158.6 157.3 156.2 165.5 98.5 105.8 77.4 11.4 113.8 136.1 167.4 410.5 131.5 47.1 180.4 265.8 302.6 178.7 195.4 171.0 12.5 277.1 111.8 126.2 469.5 239.1 950.6 159.7 159.1 129.5 149.9 152.5 9.6 277.8 404.4 146.6 65.7 122.2 92.6 202.3 144.2 374.1 263.9 43.7 10.0 188.3 244.1 147.6 117.9 523.6 153.1 109.4 193.9 10.3 301.6 133.8 121.5 7.1 16.1 247.4 160.3 147.8 171.9 250.0 153.9 538.2 157.5 47.5 111.7 132.7 155.7 534.2 195.4 188.4 157.0 215.5 98.1 244.4 221.2 182.8 MRPL53 ENSG00000204822 "Mitochondrial ribosomal protein L53" Q96EL3 2 74471982-74472687 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034612, HPA056185" Uncertain Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA034612: , HPA056185: AB_2683060" "unprognostic (2.22e-2)" "unprognostic (1.94e-2)" "unprognostic (2.81e-2)" "unprognostic (1.81e-1)" "unprognostic (2.04e-1)" "unprognostic (2.88e-2)" "prognostic unfavorable (7.36e-5)" "unprognostic (3.60e-2)" "unprognostic (1.24e-1)" "unprognostic (4.06e-2)" "prognostic favorable (1.37e-4)" "unprognostic (1.26e-1)" "prognostic unfavorable (1.16e-8)" "unprognostic (8.76e-2)" "unprognostic (2.79e-1)" "unprognostic (4.13e-1)" "unprognostic (2.45e-2)" 60.9 82.9 68.8 46.8 72.2 61.8 38.9 77.0 98.9 31.3 79.2 41.5 48.0 28.7 39.1 41.0 50.2 34.0 114.4 67.1 72.3 54.5 65.1 34.2 78.4 72.3 69.3 61.5 118.0 72.1 35.1 34.8 72.7 46.0 20.3 27.1 107.1 36.2 169.7 27.3 45.9 24.4 74.2 54.7 55.0 23.1 70.2 50.3 47.1 89.0 42.3 44.7 27.0 76.5 101.5 271.0 60.0 58.5 77.9 69.7 103.4 79.8 73.7 70.5 60.9 224.7 130.1 87.6 78.8 61.4 97.3 76.3 32.5 105.7 24.5 174.6 188.3 77.7 115.6 133.7 70.7 88.4 85.6 96.7 75.1 90.4 59.0 82.3 75.3 109.0 93.0 156.6 63.8 316.5 118.6 163.3 57.5 166.0 204.5 89.1 196.0 212.9 88.9 115.6 103.5 128.0 74.1 195.6 137.3 40.8 102.3 111.1 83.6 115.9 119.6 101.7 135.2 292.3 260.6 141.1 116.4 94.8 125.8 244.9 293.8 133.8 168.2 277.6 188.5 350.0 215.9 173.1 250.3 367.5 282.0 211.4 185.5 167.6 271.8 360.3 275.3 345.5 68.8 72.2 77.0 98.9 67.1 72.3 72.3 69.3 72.7 74.2 70.2 76.5 5.2 9.6 23.2 4.6 18.0 17.2 6.0 9.7 12.0 2.0 24.0 16.4 1.6 4.3 12.1 11.0 0.0 14.7 10.5 29.5 21.5 32.8 8.9 7.2 4.3 11.2 39.7 18.9 3.4 56.9 17.5 10.9 15.3 4.7 33.6 3.0 16.1 23.8 18.0 1.7 3.5 27.2 6.1 25.9 23.9 2.3 8.7 15.6 26.6 2.8 35.8 4.6 15.5 2.0 7.1 35.8 43.5 4.5 34.8 4.9 41.8 45.3 46.1 4.0 6.6 7.7 11.2 11.2 6.8 16.6 25.1 15.7 14.6 3.3 21.7 6.9 MRPL54 ENSG00000183617 "Mitochondrial ribosomal protein L54" Q6P161 19 3762682-3768575 "Predicted intracellular proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 427.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042117, HPA046767" Uncertain Approved Mitochondria No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA042117: AB_2677856, HPA046767: AB_2679795" "unprognostic (2.09e-1)" "unprognostic (1.00e-3)" "unprognostic (3.81e-2)" "unprognostic (1.85e-3)" "unprognostic (1.00e-1)" "unprognostic (4.43e-2)" "unprognostic (1.23e-2)" "unprognostic (1.32e-3)" "unprognostic (7.19e-2)" "unprognostic (1.70e-2)" "unprognostic (2.22e-2)" "unprognostic (2.88e-2)" "unprognostic (1.34e-3)" "unprognostic (1.78e-1)" "unprognostic (2.26e-1)" "unprognostic (2.64e-2)" "unprognostic (6.54e-3)" 56.1 85.5 68.9 41.0 69.0 109.0 54.8 70.6 80.0 47.0 70.5 54.9 53.8 49.8 36.3 58.4 57.8 34.6 78.6 67.5 70.4 78.7 122.9 43.1 63.5 69.5 68.4 46.9 87.8 71.3 64.0 31.4 69.8 57.9 44.0 38.1 71.9 37.1 57.8 55.9 48.8 37.6 69.8 54.4 70.7 54.4 70.1 63.4 57.8 57.8 50.5 50.4 43.8 72.0 115.1 64.4 58.4 57.6 34.2 54.6 49.6 53.8 69.0 126.8 108.5 55.7 39.8 82.1 54.4 66.8 47.6 71.3 77.6 70.9 53.8 53.0 118.4 41.8 33.6 72.0 89.1 89.7 95.0 64.2 121.3 53.2 92.7 49.0 105.8 56.4 80.2 157.1 67.3 77.9 81.1 94.5 77.8 79.8 46.9 69.4 33.2 122.8 97.8 57.9 81.6 67.6 43.8 103.4 83.4 27.8 69.7 126.6 75.5 79.5 45.8 136.5 117.2 95.4 140.5 82.4 78.6 142.3 60.6 96.9 121.2 81.9 103.4 132.8 96.0 139.1 112.5 122.3 134.7 125.8 107.6 99.1 35.3 133.0 133.7 122.7 168.4 144.1 68.9 69.0 70.6 80.0 67.5 70.4 69.5 68.4 69.8 69.8 70.1 72.0 61.1 76.9 79.3 5.5 101.2 49.1 91.9 111.1 63.2 55.6 89.2 98.8 55.2 91.5 91.7 79.1 18.8 134.4 69.7 183.5 358.1 112.7 94.2 90.1 54.7 60.5 105.4 63.1 3.6 193.6 125.7 62.8 90.7 78.8 106.5 47.6 62.4 249.8 157.7 38.7 4.7 234.8 79.3 115.3 65.4 63.0 56.2 90.9 71.2 2.8 120.7 105.1 106.1 2.0 10.1 128.7 185.4 44.8 123.2 116.2 234.4 427.8 76.0 90.9 26.3 65.7 64.4 113.4 47.1 106.7 57.3 176.9 94.6 109.3 171.5 118.2 MRPL57 MRP63 ENSG00000173141 "Mitochondrial ribosomal protein L57" Q9BQC6 13 21176658-21179084 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 719.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039779, HPA059370" Supported Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA039779: AB_10673362, HPA059370: AB_2683993" "unprognostic (1.00e-1)" "unprognostic (1.92e-1)" "unprognostic (4.32e-2)" "unprognostic (9.57e-3)" "unprognostic (1.51e-1)" "unprognostic (5.54e-2)" "unprognostic (1.47e-1)" "unprognostic (1.68e-1)" "unprognostic (2.64e-1)" "unprognostic (1.68e-2)" "prognostic favorable (8.35e-4)" "unprognostic (7.65e-2)" "unprognostic (2.01e-1)" "unprognostic (5.72e-2)" "unprognostic (1.32e-1)" "unprognostic (1.10e-1)" "unprognostic (6.78e-2)" 13.6 27.0 16.0 8.4 16.1 11.0 13.9 16.8 18.3 12.1 15.3 17.2 10.8 12.9 11.7 17.6 13.4 5.2 28.1 16.7 20.5 24.7 29.1 11.7 8.8 16.8 17.0 16.1 16.9 15.3 27.9 7.1 16.9 17.9 6.8 15.5 14.9 8.4 38.8 14.9 13.7 5.6 16.3 14.8 16.2 11.8 17.3 17.0 16.4 18.3 6.6 14.8 12.4 16.5 16.9 30.3 20.8 19.0 15.6 12.8 21.9 20.0 12.4 18.5 13.9 39.6 30.6 9.7 22.7 12.5 14.5 28.7 18.3 19.0 13.9 25.8 30.8 44.2 21.3 45.3 23.2 24.6 21.3 13.2 20.8 14.8 13.9 11.2 17.9 39.0 19.5 12.4 13.2 59.3 53.7 64.8 15.1 54.8 35.0 32.1 31.4 17.2 23.1 20.3 41.4 19.4 16.2 20.1 31.2 14.0 20.2 22.8 12.6 9.6 17.9 20.5 17.9 17.2 14.9 17.7 8.6 28.5 24.6 51.1 70.4 56.3 49.8 59.0 56.4 63.1 62.4 53.2 64.0 60.5 69.6 55.6 10.4 54.5 50.4 102.2 70.2 72.4 16.0 16.1 16.8 18.3 16.7 20.5 16.8 17.0 16.9 16.3 17.3 16.5 93.3 80.1 124.4 12.1 95.4 0.0 107.2 0.0 84.2 88.3 172.1 195.7 495.7 140.2 56.3 176.6 45.9 233.6 118.8 171.7 508.7 159.8 256.0 188.6 98.8 91.6 149.5 165.6 16.8 245.1 205.0 94.2 116.2 107.6 72.2 104.5 117.8 478.4 231.4 77.4 21.3 218.9 0.0 126.6 0.0 341.6 115.2 104.1 0.0 8.4 166.2 181.4 109.2 6.6 17.9 171.6 190.7 98.9 141.9 160.4 266.5 719.5 80.9 100.7 52.6 69.0 74.0 83.6 48.9 175.7 0.0 223.1 99.0 179.5 204.1 112.2 MRPL9 ENSG00000143436 "Mitochondrial ribosomal protein L9" Q9BYD2 1 151759647-151763496 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008579 Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA008579: AB_1079412" "unprognostic (2.55e-1)" "unprognostic (1.75e-1)" "unprognostic (2.34e-1)" "unprognostic (7.43e-3)" "unprognostic (7.66e-2)" "unprognostic (2.73e-1)" "prognostic unfavorable (1.04e-7)" "unprognostic (1.47e-1)" "unprognostic (5.22e-2)" "unprognostic (9.51e-3)" "unprognostic (1.18e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (1.44e-5)" "unprognostic (1.79e-1)" "unprognostic (1.79e-1)" "unprognostic (2.10e-2)" "unprognostic (6.30e-2)" 33.2 27.6 26.2 28.6 27.3 41.1 33.5 29.5 29.3 28.7 24.9 35.1 27.0 33.0 30.9 32.2 28.8 21.2 31.0 26.9 29.4 35.6 29.8 25.4 39.9 28.4 27.7 32.6 30.4 49.0 22.6 29.1 28.2 30.8 28.0 18.1 40.4 28.6 71.3 35.1 29.4 28.9 28.2 32.2 30.7 24.5 27.4 46.5 30.8 55.3 38.8 32.2 28.4 28.8 120.3 98.6 63.8 74.6 44.9 50.5 103.9 66.4 62.7 102.3 80.5 151.9 113.3 79.5 126.7 67.8 65.7 106.3 111.8 84.8 81.6 107.3 107.2 64.0 81.7 99.5 71.4 177.1 56.7 56.3 77.7 89.7 113.6 68.3 100.2 119.7 133.3 104.4 80.5 284.6 112.9 134.8 134.6 139.4 141.1 93.6 74.0 155.7 63.0 96.5 103.2 108.2 79.5 113.1 98.7 88.6 169.4 210.1 69.4 79.2 79.5 66.6 149.5 113.2 168.1 252.5 96.2 116.8 91.7 58.1 42.7 29.5 82.0 54.4 94.7 96.2 94.4 96.3 98.7 89.0 89.1 84.8 5.2 85.4 49.0 83.0 122.0 73.5 26.2 27.3 29.5 29.3 26.9 29.4 28.4 27.7 28.2 28.2 27.4 28.8 31.5 28.9 21.8 8.1 41.0 31.4 48.0 52.9 30.7 19.9 46.2 51.3 4.3 28.6 38.1 33.1 6.2 98.4 43.4 17.2 64.6 69.6 100.0 21.9 27.6 43.8 28.7 39.5 7.5 64.4 124.4 29.2 19.4 22.1 41.1 44.8 43.9 28.4 65.6 18.5 7.7 31.6 42.7 32.4 38.2 36.0 39.1 26.6 35.6 3.7 64.0 32.1 54.6 7.1 7.8 67.1 24.6 47.0 26.9 44.6 29.5 86.8 33.4 19.8 72.3 37.6 35.5 56.3 36.4 33.0 31.7 74.6 43.9 42.5 46.8 40.2 MRPS11 "FLJ22512, FLJ23406, HCC-2" ENSG00000181991 "Mitochondrial ribosomal protein S11" P82912 15 88467453-88480776 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043752, HPA050345" Enhanced Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA043752: AB_2678653, HPA050345: AB_2681100" "unprognostic (2.66e-1)" "prognostic favorable (3.60e-4)" "unprognostic (6.51e-2)" "unprognostic (1.35e-1)" "unprognostic (1.12e-1)" "unprognostic (3.21e-1)" "unprognostic (3.45e-1)" "unprognostic (1.44e-1)" "unprognostic (6.45e-2)" "prognostic favorable (4.75e-4)" "unprognostic (8.31e-2)" "unprognostic (3.37e-1)" "unprognostic (1.83e-1)" "unprognostic (9.44e-2)" "unprognostic (7.26e-2)" "unprognostic (7.85e-2)" "unprognostic (1.74e-1)" 9.4 16.9 12.0 4.0 12.1 2.8 8.6 12.8 18.3 5.3 11.4 9.3 7.9 5.3 3.8 10.9 4.8 4.5 26.1 12.5 12.1 14.0 20.5 5.2 5.6 12.7 12.3 3.5 10.5 3.8 7.6 2.3 12.9 7.4 3.5 2.5 6.0 3.4 24.7 7.2 7.4 4.3 11.7 8.0 9.6 9.0 12.7 5.1 9.6 15.0 4.4 8.4 5.6 12.1 10.5 41.1 6.1 10.4 13.8 6.6 16.1 8.3 14.6 10.7 11.5 28.9 16.0 9.7 17.0 7.1 11.3 14.8 17.9 11.5 5.5 12.8 43.8 13.2 23.1 32.0 16.5 4.5 8.3 13.4 11.1 9.2 9.2 5.8 14.3 12.3 9.6 4.3 18.1 45.1 9.3 19.0 16.3 13.4 43.8 19.0 11.6 23.0 15.5 28.4 19.3 9.6 8.6 21.6 33.6 5.3 19.8 24.7 6.8 15.2 16.8 9.9 12.5 8.5 16.5 11.7 18.3 11.2 16.3 31.1 25.1 19.3 15.1 27.6 17.6 27.5 17.2 17.8 29.5 18.2 18.1 17.6 9.5 30.1 17.8 31.9 35.1 26.0 12.0 12.1 12.8 18.3 12.5 12.1 12.7 12.3 12.9 11.7 12.7 12.1 42.1 6.4 20.4 10.4 30.4 22.8 27.5 69.2 31.9 36.9 38.1 47.2 6.3 35.8 39.6 46.0 47.9 91.0 34.6 85.5 135.0 63.9 30.2 27.1 37.8 34.2 24.7 40.6 14.0 66.8 89.7 32.7 25.0 32.5 33.6 40.4 44.6 92.6 90.5 26.9 15.0 60.3 50.8 33.1 24.5 34.2 33.2 31.0 32.0 8.4 65.0 44.4 72.1 16.6 16.8 67.0 70.7 42.5 36.5 32.2 90.8 145.3 29.7 45.1 19.7 29.7 51.8 90.3 42.0 49.1 28.3 89.6 32.3 96.0 64.6 34.5 MRPS15 FLJ11564 ENSG00000116898 "Mitochondrial ribosomal protein S15" P82914 1 36455718-36464384 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 287.3" "Cell type enhanced" "Detected in all" "Early spermatids: 776.7;Late spermatids: 2209.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028100, HPA028134, HPA067137" Supported Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "HPA028100: AB_10600216, HPA028134: AB_10600890, HPA067137: AB_2685787" "unprognostic (2.05e-2)" "unprognostic (6.98e-2)" "unprognostic (7.57e-2)" "unprognostic (4.53e-1)" "unprognostic (3.29e-2)" "unprognostic (1.44e-1)" "prognostic unfavorable (3.59e-4)" "unprognostic (2.20e-2)" "unprognostic (3.28e-2)" "prognostic favorable (7.83e-4)" "unprognostic (8.48e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (3.55e-4)" "unprognostic (2.31e-1)" "unprognostic (1.44e-1)" "unprognostic (8.94e-2)" "unprognostic (1.39e-1)" 77.3 68.9 54.1 37.4 55.7 81.7 62.4 58.5 70.4 38.8 61.8 63.7 41.1 42.5 62.6 70.9 37.1 30.2 133.8 54.8 59.8 82.0 122.1 47.4 45.4 57.9 56.8 33.2 63.2 77.0 46.3 45.0 58.3 45.1 50.7 21.0 58.1 37.8 287.3 53.0 41.6 40.0 54.4 41.3 68.7 151.2 58.1 44.1 40.0 196.9 47.9 54.2 43.0 56.0 162.3 88.7 94.4 115.8 91.9 132.6 233.9 88.3 126.1 214.3 195.7 157.9 169.3 148.8 140.0 117.3 128.1 138.9 139.5 223.3 192.3 97.4 177.0 152.5 104.1 175.2 171.6 190.2 103.2 123.1 196.1 191.2 153.7 82.5 178.0 109.5 168.1 114.0 134.5 112.2 184.7 203.8 169.8 137.2 154.2 140.4 165.6 218.6 193.0 135.1 139.4 77.0 122.2 153.9 236.0 139.7 95.1 129.0 84.3 119.7 126.8 149.0 189.4 113.2 169.1 211.3 136.1 128.1 170.8 18.7 78.9 22.3 61.8 89.7 77.3 72.5 70.3 71.2 122.0 73.5 65.6 64.4 5.3 64.5 61.2 83.6 87.8 90.7 54.1 55.7 58.5 70.4 54.8 59.8 57.9 56.8 58.3 54.4 58.1 56.0 50.6 38.5 52.0 10.1 57.2 65.4 70.3 119.6 55.8 23.2 85.6 79.9 136.7 65.8 74.7 71.7 14.6 245.9 49.2 84.8 322.9 132.8 776.7 53.2 58.6 62.6 66.0 118.2 8.7 162.4 260.3 61.7 69.3 75.4 42.5 71.1 62.4 140.6 153.8 13.5 8.7 97.7 85.5 81.1 68.9 2209.2 62.7 75.7 56.9 4.7 86.7 31.3 56.7 5.5 7.2 143.1 64.2 74.4 108.4 128.8 118.3 361.6 50.3 23.5 65.7 56.3 103.2 502.4 76.0 107.0 80.4 281.6 59.0 113.1 127.2 118.3 MRPS2 CGI-91 ENSG00000122140 "Mitochondrial ribosomal protein S2" Q9Y399 9 135499984-135504673 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029487, HPA057261" Approved Supported Mitochondria NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Mitochondria "HPA029487: , HPA057261: AB_2683385" "unprognostic (3.18e-3)" "unprognostic (9.42e-3)" "unprognostic (1.46e-1)" "unprognostic (7.81e-2)" "unprognostic (3.55e-1)" "unprognostic (8.45e-2)" "unprognostic (1.63e-1)" "unprognostic (5.63e-3)" "unprognostic (3.83e-1)" "unprognostic (2.90e-2)" "unprognostic (4.81e-2)" "unprognostic (7.58e-2)" "prognostic favorable (6.96e-9)" "unprognostic (2.74e-2)" "unprognostic (1.06e-1)" "unprognostic (8.29e-2)" "unprognostic (2.24e-1)" 32.6 56.9 30.7 14.7 31.3 23.2 30.8 30.3 37.9 29.2 34.9 35.4 23.0 29.6 12.9 37.7 35.7 15.8 67.0 31.2 30.2 46.1 79.7 22.0 21.0 29.9 31.3 34.9 45.8 32.2 26.4 16.8 31.1 33.1 17.3 7.7 31.3 21.2 75.5 39.1 28.1 15.2 29.7 32.0 39.3 17.0 33.1 16.2 25.8 50.4 17.7 33.8 28.8 30.8 59.9 98.4 35.3 48.0 39.1 43.5 60.0 43.0 39.0 71.7 53.0 149.0 55.4 75.4 57.2 40.1 75.8 132.6 88.9 101.4 27.7 46.2 137.4 37.4 96.1 101.8 68.4 76.6 44.3 58.6 77.6 78.3 55.6 45.7 67.9 74.2 125.1 54.3 42.3 185.8 73.9 133.7 80.2 110.8 153.9 81.3 57.3 159.5 59.9 50.8 104.9 55.2 58.8 110.9 63.2 23.6 92.4 60.5 42.4 52.3 58.4 90.3 78.8 58.9 124.5 84.1 53.0 69.2 49.1 8.4 28.4 13.6 30.0 27.5 34.5 34.4 30.1 32.4 29.1 34.3 32.4 32.9 2.4 28.7 24.0 25.1 41.8 26.4 30.7 31.3 30.3 37.9 31.2 30.2 29.9 31.3 31.1 29.7 33.1 30.8 23.8 12.8 14.1 4.9 32.5 44.7 38.8 55.0 33.0 22.2 37.3 51.7 31.2 42.9 31.6 12.9 6.2 71.3 19.0 21.5 72.4 50.7 14.7 27.8 34.2 32.6 21.7 41.4 4.6 38.6 65.8 27.9 21.4 77.7 8.2 37.9 21.8 46.5 42.5 25.2 5.9 37.9 28.5 17.6 15.4 32.5 24.2 21.0 19.6 1.9 31.7 24.8 20.6 4.0 4.5 39.9 27.1 23.0 38.6 48.6 36.3 84.5 14.7 17.0 32.9 27.1 29.4 13.3 21.5 47.1 45.7 37.4 23.4 77.5 55.7 35.5 MRPS21 ENSG00000266472 "Mitochondrial ribosomal protein S21" P82921 1 150293861-150308979 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 863.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078289 Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA078289: AB_2686881" "unprognostic (3.48e-2)" "unprognostic (1.94e-2)" "unprognostic (5.46e-2)" "unprognostic (2.33e-1)" "unprognostic (2.88e-1)" "unprognostic (8.45e-2)" "prognostic unfavorable (2.62e-4)" "unprognostic (1.15e-2)" "unprognostic (2.60e-1)" "unprognostic (3.14e-2)" "unprognostic (4.13e-2)" "unprognostic (9.71e-2)" "unprognostic (7.59e-2)" "unprognostic (2.12e-2)" "unprognostic (4.02e-2)" "unprognostic (3.97e-2)" "unprognostic (1.46e-1)" 46.8 76.7 91.7 35.7 93.8 39.0 51.7 92.9 121.4 48.7 97.4 51.8 38.4 46.7 53.7 54.5 46.3 27.6 72.7 93.2 95.0 67.1 59.9 39.2 42.8 93.8 92.7 56.6 51.1 65.4 70.1 32.5 94.5 51.5 28.9 42.3 43.7 39.1 55.6 45.0 45.2 38.7 89.0 53.3 52.1 52.2 95.2 49.0 53.1 66.5 46.6 47.9 45.8 92.3 112.7 88.4 112.9 57.5 108.3 108.2 93.9 80.5 69.1 77.0 74.5 18.0 101.6 111.9 54.2 89.3 22.8 102.9 96.8 86.4 67.8 77.7 125.9 64.3 133.4 137.0 84.7 98.4 53.8 119.2 87.0 93.4 105.8 47.0 100.3 96.8 106.7 144.3 107.1 255.8 84.3 89.1 196.0 216.3 159.3 75.9 59.0 195.8 93.7 79.9 83.7 182.1 68.4 131.9 136.4 126.3 73.4 143.0 71.7 28.1 56.7 81.6 90.9 120.4 136.4 112.7 39.5 53.1 58.3 41.1 78.4 50.7 70.1 79.7 86.6 116.8 92.7 82.5 89.1 102.1 103.8 89.6 17.8 71.5 73.6 136.2 97.2 104.9 91.7 93.8 92.9 121.4 93.2 95.0 93.8 92.7 94.5 89.0 95.2 92.3 124.7 112.2 115.8 24.8 152.7 120.3 199.9 466.6 191.8 72.6 189.3 246.4 295.6 201.6 227.8 263.0 33.3 283.8 110.4 114.4 526.3 226.2 863.2 217.2 216.0 150.2 138.5 151.7 31.8 311.4 245.5 172.3 152.4 155.7 132.9 157.8 189.2 366.9 288.2 48.8 34.7 141.6 266.5 196.2 162.3 605.4 230.2 143.7 181.5 18.7 234.1 140.3 118.4 23.1 27.1 300.8 133.1 233.2 156.5 197.6 230.1 703.7 291.7 59.5 98.6 115.4 211.1 276.4 112.1 262.6 147.2 235.2 144.4 183.8 168.5 200.9 MRPS22 "C3orf5, GIBT, GK002, MRP-S22" ENSG00000175110 "Mitochondrial ribosomal protein S22" P82650 3 139005806-139357223 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006083, HPA007830" Enhanced Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "HPA006083: AB_1854122, HPA007830: AB_1854123" "unprognostic (8.38e-2)" "unprognostic (1.52e-2)" "unprognostic (3.04e-2)" "prognostic unfavorable (1.35e-5)" "unprognostic (5.22e-3)" "unprognostic (5.45e-3)" "unprognostic (4.85e-2)" "unprognostic (2.18e-2)" "unprognostic (2.78e-2)" "unprognostic (4.49e-3)" "prognostic unfavorable (1.55e-5)" "prognostic unfavorable (1.85e-4)" "unprognostic (3.22e-3)" "unprognostic (2.56e-2)" "unprognostic (1.49e-1)" "unprognostic (1.77e-1)" "unprognostic (3.40e-1)" 25.5 55.6 23.1 20.7 24.2 37.9 25.2 27.2 31.5 21.9 22.2 35.0 37.0 20.2 19.3 37.4 20.5 17.3 61.3 23.4 27.3 38.0 57.4 17.0 22.8 24.9 23.4 22.6 32.0 31.7 13.7 25.6 26.0 17.1 31.9 17.9 22.0 20.2 83.0 21.8 33.1 23.9 25.8 17.0 25.0 35.4 24.4 23.5 22.8 77.3 24.4 27.3 21.6 27.4 101.2 40.4 40.0 44.5 49.1 41.7 79.1 58.9 72.3 97.1 80.7 130.0 68.3 66.5 106.9 67.1 98.9 109.9 64.6 76.5 96.4 39.0 64.1 105.2 35.8 97.2 56.2 99.3 58.1 45.2 59.6 58.3 61.8 49.2 61.0 76.2 149.2 41.7 61.2 72.4 51.9 85.9 64.4 102.3 73.3 65.0 61.3 98.9 75.0 61.4 43.4 40.4 94.2 141.4 154.6 37.0 97.1 93.7 47.5 42.4 42.3 82.4 55.9 66.3 38.5 119.5 56.9 70.6 42.3 42.8 38.4 36.1 34.9 53.4 43.0 40.3 37.5 39.4 45.8 36.1 41.0 38.9 9.2 38.1 53.6 29.7 47.6 36.3 23.1 24.2 27.2 31.5 23.4 27.3 24.9 23.4 26.0 25.8 24.4 27.4 30.7 19.2 13.4 8.8 21.8 22.8 29.7 63.3 19.4 19.9 15.3 18.0 50.3 25.8 33.3 18.4 14.6 62.9 24.9 26.5 68.4 47.5 84.3 19.9 30.5 26.6 15.6 31.2 8.7 60.3 48.0 27.7 16.3 22.0 27.3 24.9 18.2 38.9 48.6 20.2 13.8 26.5 32.6 21.9 16.1 14.3 23.3 22.5 16.0 4.7 38.0 21.8 24.7 10.1 10.1 42.0 27.1 23.7 38.4 16.6 45.4 59.4 35.5 26.2 39.5 32.2 39.1 102.2 51.4 34.8 20.5 75.4 24.7 74.1 46.5 31.2 MRPS25 "DKFZp313H0817, FLJ00023, MRP-S25, RPMS25" ENSG00000131368 "Mitochondrial ribosomal protein S25" P82663 3 15042460-15065317 "Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 367.5;Late spermatids: 1316.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043490 Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 28: BEWO - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "HPA043490: AB_10794888" "unprognostic (3.98e-2)" "unprognostic (5.36e-2)" "unprognostic (4.58e-3)" "unprognostic (1.24e-2)" "unprognostic (4.66e-2)" "unprognostic (1.82e-2)" "unprognostic (3.33e-2)" "unprognostic (4.93e-3)" "unprognostic (2.23e-1)" "unprognostic (2.10e-1)" "unprognostic (6.29e-2)" "unprognostic (2.68e-3)" "prognostic favorable (3.60e-7)" "unprognostic (2.84e-2)" "unprognostic (1.93e-1)" "unprognostic (5.06e-2)" "unprognostic (2.91e-3)" 20.5 23.7 14.4 18.1 14.2 12.5 19.1 15.0 15.3 21.7 23.6 33.0 29.7 20.0 11.0 25.4 22.7 8.2 68.0 13.4 13.9 33.4 46.5 22.7 17.6 13.2 13.9 25.9 21.1 19.1 32.1 10.3 13.8 22.6 20.8 43.4 19.6 13.6 54.8 22.2 29.8 12.6 11.8 26.0 26.3 35.2 14.0 9.7 43.5 28.8 17.6 25.9 21.9 12.4 18.0 26.1 20.9 29.2 21.7 18.4 66.8 24.1 9.3 19.0 16.3 29.9 19.1 46.8 12.5 10.6 12.6 22.8 30.5 22.8 16.3 18.8 42.9 38.9 60.2 37.6 15.1 34.7 28.5 22.4 21.2 29.9 9.1 12.9 17.9 31.2 42.0 27.3 14.3 57.3 27.3 33.5 21.7 41.6 41.1 36.5 18.1 48.7 23.9 30.7 16.5 24.9 17.6 33.0 35.9 12.8 44.7 29.9 22.1 17.1 25.2 23.7 30.6 26.3 30.1 33.7 17.3 43.8 16.3 3.3 27.2 7.2 17.4 34.6 20.2 39.4 16.2 18.0 29.3 35.2 25.6 21.0 1.8 13.8 37.2 24.0 14.2 18.1 14.4 14.2 15.0 15.3 13.4 13.9 13.2 13.9 13.8 11.8 14.0 12.4 22.8 51.3 34.6 47.3 49.4 38.5 61.0 76.2 31.9 58.2 37.2 39.9 271.5 44.3 57.7 36.8 164.7 94.6 30.5 78.5 223.0 50.0 367.5 31.1 45.1 31.0 54.0 36.6 37.7 34.0 74.6 40.0 51.0 28.3 26.0 45.5 21.0 101.0 93.4 67.3 43.9 81.3 54.9 29.8 36.6 1316.8 46.0 35.3 37.4 8.4 41.0 25.7 43.3 32.2 29.3 47.4 49.5 30.1 41.6 74.4 152.8 201.6 40.7 106.2 72.3 35.6 43.0 139.1 30.0 56.1 48.6 72.7 28.4 97.4 125.8 73.9 MRPS26 "C20orf193, dJ534B8.3, MRP-S13, MRP-S26, RPMS13" ENSG00000125901 "Mitochondrial ribosomal protein S26" Q9BYN8 20 3046052-3048250 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045472, HPA054610" Supported Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA045472: AB_10962052, HPA054610: AB_2682541" "unprognostic (1.53e-1)" "unprognostic (2.18e-1)" "unprognostic (3.71e-1)" "unprognostic (4.41e-2)" "unprognostic (1.21e-1)" "unprognostic (1.68e-1)" "unprognostic (8.13e-3)" "unprognostic (3.14e-1)" "unprognostic (6.83e-2)" "unprognostic (8.21e-2)" "unprognostic (9.65e-3)" "unprognostic (2.14e-1)" "unprognostic (1.14e-2)" "unprognostic (3.77e-1)" "unprognostic (4.11e-2)" "unprognostic (2.95e-1)" "unprognostic (3.93e-3)" 36.9 69.5 61.1 17.1 62.4 18.1 38.3 63.9 69.6 41.6 64.2 50.8 26.9 40.9 34.8 48.6 42.4 11.3 69.7 59.7 65.3 60.6 104.1 27.9 19.2 64.8 62.0 48.0 50.0 38.9 64.8 19.4 63.5 56.3 18.8 14.2 41.0 30.4 56.7 48.6 35.7 19.8 60.6 34.9 45.4 21.3 63.5 18.3 51.1 25.6 20.9 48.6 38.3 63.7 119.0 157.5 34.7 63.6 37.3 28.4 91.0 45.4 30.6 51.4 39.2 138.9 53.0 117.7 56.3 23.7 67.0 109.9 69.6 94.1 29.9 30.2 149.0 53.6 60.8 234.6 51.9 85.2 25.3 32.0 72.0 42.7 64.2 35.7 38.7 68.9 88.1 27.0 31.1 103.6 88.4 149.6 170.8 89.9 154.0 96.4 60.0 126.5 51.2 78.9 108.9 140.7 52.0 171.7 109.2 34.3 77.4 47.5 36.2 33.2 52.6 60.0 84.9 120.0 169.0 72.6 21.6 70.7 37.8 36.1 64.2 33.0 68.6 77.5 87.9 114.4 76.3 74.6 87.5 104.9 87.3 74.9 5.1 97.0 63.6 53.3 65.9 73.2 61.1 62.4 63.9 69.6 59.7 65.3 64.8 62.0 63.5 60.6 63.5 63.7 50.9 16.0 26.8 18.3 61.4 82.0 62.9 113.7 86.6 40.0 87.4 136.5 64.6 54.3 61.5 55.2 35.5 188.1 50.2 72.6 209.4 77.6 4.3 56.9 70.8 43.1 55.1 49.2 20.3 54.8 117.5 57.6 60.1 50.3 14.0 94.0 32.5 120.0 81.1 47.1 20.3 104.1 103.7 23.6 37.5 10.6 69.0 29.2 67.6 5.6 35.3 88.5 56.7 18.1 19.3 52.6 62.0 61.7 46.2 115.3 108.6 239.8 44.4 45.4 59.2 47.3 66.8 60.8 68.7 101.9 92.2 78.5 44.8 164.6 124.2 54.0 MRPS28 "HSPC007, MRP-S28, MRPS35" ENSG00000147586 "Mitochondrial ribosomal protein S28" Q9Y2Q9 8 79918717-80030289 "Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 359.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027202 Approved Supported Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Mitochondria "HPA027202: AB_1854126" "unprognostic (3.63e-3)" "unprognostic (6.41e-2)" "unprognostic (9.61e-3)" "unprognostic (1.31e-1)" "unprognostic (4.41e-2)" "unprognostic (1.43e-3)" "unprognostic (2.17e-1)" "unprognostic (1.27e-1)" "unprognostic (3.23e-1)" "unprognostic (4.55e-1)" "unprognostic (4.18e-1)" "unprognostic (2.11e-1)" "prognostic favorable (1.20e-6)" "unprognostic (4.48e-2)" "unprognostic (3.13e-1)" "unprognostic (1.18e-1)" "unprognostic (7.18e-2)" 47.5 88.8 65.1 32.9 67.7 29.1 47.5 70.0 85.3 33.3 73.0 52.9 30.9 27.3 38.3 41.0 35.2 28.8 104.0 64.0 70.2 79.2 110.9 30.4 37.7 70.1 69.8 28.6 32.3 69.6 40.4 40.9 70.1 31.3 41.0 51.7 35.4 33.4 160.3 29.0 29.4 32.8 69.7 26.7 35.3 24.3 66.9 44.9 53.7 137.7 37.9 39.0 30.7 75.3 85.2 84.1 73.0 17.3 60.9 77.2 79.8 94.3 85.7 122.1 104.2 74.0 66.4 107.2 105.3 75.6 124.2 68.5 102.1 105.5 99.0 85.3 89.8 128.8 74.8 114.4 67.7 57.6 55.3 66.4 88.9 71.8 97.4 67.1 81.0 85.2 93.4 42.3 123.7 81.3 133.8 93.5 29.8 219.5 139.5 89.9 58.1 62.0 158.0 81.8 34.8 58.6 41.1 359.5 91.1 83.8 86.6 68.1 59.0 45.8 116.4 81.6 82.7 46.5 81.4 97.2 77.4 66.7 36.8 95.4 53.8 29.1 48.2 77.3 52.3 51.2 52.8 59.4 98.8 54.4 64.1 62.1 11.1 71.5 70.1 111.1 73.0 49.8 65.1 67.7 70.0 85.3 64.0 70.2 70.1 69.8 70.1 69.7 66.9 75.3 32.5 22.4 22.2 57.8 20.8 35.2 19.5 124.5 36.5 10.9 23.4 28.1 51.6 42.9 67.0 33.1 4.2 78.7 20.9 18.1 101.8 67.3 15.1 28.5 16.1 26.2 37.3 21.7 39.0 47.4 74.3 21.2 17.9 24.1 50.0 10.5 23.9 65.5 49.5 5.0 42.5 23.5 69.2 25.5 28.5 10.4 17.7 26.9 44.4 70.3 40.0 23.7 26.8 93.5 81.8 36.0 20.6 22.2 19.9 13.4 24.5 126.9 79.7 17.2 32.9 31.1 26.1 18.6 33.4 41.6 37.8 59.4 20.0 23.2 36.4 16.0 MRPS34 "MGC2616, MRP-S12" ENSG00000074071 "Mitochondrial ribosomal protein S34" P82930 16 1771890-1773150 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEK 293: 354.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042112 Supported Supported Mitochondria NA NA "Cluster 24: B-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA042112: AB_10796899" "unprognostic (2.02e-1)" "unprognostic (4.83e-2)" "unprognostic (6.79e-2)" "unprognostic (3.42e-2)" "unprognostic (2.27e-1)" "unprognostic (9.59e-2)" "unprognostic (1.42e-2)" "unprognostic (2.49e-1)" "unprognostic (3.03e-1)" "unprognostic (2.22e-2)" "unprognostic (1.81e-1)" "unprognostic (1.50e-1)" "unprognostic (3.52e-1)" "unprognostic (1.37e-2)" "unprognostic (6.60e-2)" "unprognostic (3.18e-1)" "unprognostic (5.44e-2)" 40.2 84.4 15.0 8.2 15.6 14.9 38.9 18.8 30.2 39.6 8.4 56.9 17.6 41.4 1.8 74.2 38.1 3.9 66.5 14.3 14.7 53.4 83.8 33.1 9.6 20.1 14.9 32.5 85.4 7.5 43.2 6.0 18.3 44.2 3.0 1.5 51.9 9.7 88.1 63.3 48.9 3.0 17.3 59.4 55.9 22.3 17.2 6.6 35.2 6.2 4.3 43.9 43.6 19.7 72.4 77.1 10.6 26.9 9.1 10.7 86.5 75.8 14.9 26.2 20.2 51.7 40.7 89.1 120.7 9.6 14.9 82.3 15.7 37.3 4.0 63.2 354.6 63.9 68.2 56.3 19.9 116.7 63.3 9.8 17.5 16.1 7.1 11.8 20.4 45.1 105.7 18.6 7.5 113.3 63.1 209.4 101.5 19.1 229.5 137.9 51.9 201.0 10.2 19.4 132.2 100.6 85.8 42.4 82.5 2.9 54.9 46.5 51.9 28.2 88.9 37.1 62.8 154.8 116.9 141.9 22.1 65.3 36.1 68.6 185.4 108.3 144.9 172.6 153.3 189.3 160.0 154.2 205.6 224.2 150.2 135.6 40.6 165.1 153.9 192.1 204.7 189.6 15.0 15.6 18.8 30.2 14.3 14.7 20.1 14.9 18.3 17.3 17.2 19.7 72.0 38.5 31.7 13.1 92.5 100.3 60.8 132.6 103.6 45.6 108.8 127.9 59.9 101.5 77.3 97.5 10.4 181.3 87.9 170.1 250.5 116.1 5.9 65.3 82.8 59.6 91.1 90.6 10.1 182.5 181.9 66.2 105.0 66.2 36.1 75.6 65.3 168.1 173.3 55.5 12.0 174.0 109.9 96.1 66.2 11.6 72.7 74.8 81.8 8.4 108.8 87.8 110.2 11.6 17.1 155.4 153.4 70.0 183.8 94.0 265.6 261.8 43.1 38.2 19.7 48.2 73.7 30.9 49.2 192.3 120.6 68.4 83.2 140.7 232.3 75.7 MRPS36 "DC47, MRP-S36" ENSG00000134056 "Mitochondrial ribosomal protein S36" P82909 5 69217760-69230158 "Predicted intracellular proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 546.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035802, HPA056795" Supported Enhanced Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA035802: AB_10600933, HPA056795: AB_2683237" "unprognostic (1.19e-1)" "unprognostic (6.78e-3)" "unprognostic (4.08e-2)" "unprognostic (1.02e-1)" "unprognostic (1.92e-1)" "unprognostic (2.96e-3)" "unprognostic (1.99e-1)" "unprognostic (7.49e-2)" "unprognostic (1.49e-1)" "unprognostic (1.99e-2)" "unprognostic (1.38e-1)" "unprognostic (3.90e-1)" "prognostic favorable (5.02e-6)" "unprognostic (2.06e-1)" "unprognostic (2.49e-1)" "unprognostic (1.37e-2)" "unprognostic (4.84e-3)" 20.3 18.4 20.1 12.7 20.3 21.0 16.5 21.3 26.3 12.7 20.2 23.6 24.1 12.8 15.4 20.3 12.7 10.4 67.3 20.1 21.5 49.2 38.0 14.7 15.1 20.3 20.6 12.4 14.7 31.3 9.8 13.0 20.6 14.4 24.3 18.9 13.7 12.1 47.0 12.6 24.0 12.4 20.3 11.6 21.8 8.6 20.8 15.7 17.2 67.7 16.7 16.6 14.0 20.5 29.2 27.6 19.1 26.4 32.8 33.1 50.3 25.6 24.5 32.1 39.4 38.6 31.8 31.2 51.9 21.8 71.8 29.3 32.1 38.8 31.7 36.8 33.6 21.3 31.4 43.4 38.7 22.9 27.9 34.6 27.3 30.7 14.5 33.4 24.0 31.9 25.7 22.9 28.7 31.8 35.3 34.9 14.2 26.8 31.9 20.6 33.2 47.9 56.4 32.5 26.6 25.9 26.2 37.9 46.3 30.9 29.0 32.9 17.6 14.3 24.5 32.0 44.5 23.9 41.9 41.6 25.0 42.1 19.1 36.3 22.1 29.3 22.7 32.0 25.4 31.1 25.7 25.8 27.9 25.0 22.8 24.7 25.1 26.5 30.2 27.4 40.3 17.7 20.1 20.3 21.3 26.3 20.1 21.5 20.3 20.6 20.6 20.3 20.8 20.5 64.5 115.4 83.6 16.3 76.5 81.4 101.1 204.0 83.1 26.3 72.4 109.3 333.1 97.2 104.3 88.3 14.6 126.8 67.5 220.5 401.1 118.4 127.7 123.3 79.5 57.2 92.8 97.2 20.4 139.5 192.4 68.6 67.2 113.0 56.4 41.4 52.1 216.1 127.1 28.6 21.4 162.8 120.1 102.4 67.5 45.2 64.7 72.9 106.7 10.3 142.0 61.8 56.7 10.6 17.1 137.1 190.1 69.2 60.5 100.5 256.6 546.3 86.4 45.9 72.3 78.7 92.3 66.1 37.9 86.9 76.9 123.3 64.2 76.9 168.1 114.6 MRPS5 "MRP-S5, S5mt" ENSG00000144029 "Mitochondrial ribosomal protein S5" P82675 2 95085369-95149434 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055765 Approved Supported Mitochondria No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA055765: AB_2682911" "unprognostic (1.18e-1)" "unprognostic (7.79e-2)" "unprognostic (1.73e-2)" "prognostic unfavorable (7.98e-7)" "unprognostic (7.51e-3)" "unprognostic (6.30e-3)" "prognostic unfavorable (7.73e-5)" "unprognostic (8.59e-2)" "unprognostic (1.87e-1)" "unprognostic (2.76e-2)" "unprognostic (1.11e-1)" "unprognostic (1.99e-2)" "unprognostic (1.32e-2)" "unprognostic (2.34e-2)" "unprognostic (1.29e-1)" "prognostic favorable (6.36e-4)" "unprognostic (1.25e-1)" 26.0 33.6 5.6 3.8 5.7 7.6 22.3 6.9 7.1 24.4 6.3 34.5 6.9 24.1 4.7 34.5 24.3 3.6 53.6 5.7 5.6 34.6 53.6 24.3 5.5 5.7 5.5 24.9 24.1 6.8 19.9 3.7 5.8 18.5 6.9 5.0 24.7 2.9 71.2 19.4 26.8 5.1 5.1 25.0 30.1 19.5 5.8 6.2 23.8 13.7 5.4 23.7 24.8 6.3 18.8 14.8 8.1 7.8 8.6 10.6 15.3 9.5 4.2 7.1 7.6 28.7 12.9 18.4 7.5 8.4 17.1 11.3 14.0 11.8 13.8 13.0 11.2 11.6 12.3 22.8 11.6 16.5 7.3 10.5 9.3 12.0 12.5 9.0 12.3 10.4 18.0 7.8 10.4 15.1 18.6 17.8 9.0 16.5 13.5 10.5 8.0 21.3 17.4 18.5 12.4 7.8 8.2 17.2 17.6 12.8 7.4 16.0 9.5 10.6 12.9 15.1 15.5 7.6 8.9 14.0 8.8 16.3 9.6 2.5 5.4 3.8 3.6 7.2 4.4 4.5 4.8 4.2 4.8 3.3 4.2 4.4 2.2 3.6 7.4 3.3 5.9 4.2 5.6 5.7 6.9 7.1 5.7 5.6 5.7 5.5 5.8 5.1 5.8 6.3 46.3 80.1 84.6 33.3 52.3 34.8 59.1 112.5 56.9 52.8 42.1 40.5 130.2 58.6 74.4 66.2 50.1 81.8 51.2 68.3 185.9 74.8 68.3 48.5 69.9 48.1 59.4 79.3 31.8 55.4 83.8 53.9 51.0 43.0 40.4 90.7 50.3 129.8 74.1 47.1 29.3 65.0 109.9 51.8 41.2 48.9 51.3 55.3 44.4 7.5 61.5 29.7 44.3 30.7 40.3 50.2 44.2 53.4 69.7 68.1 87.3 131.8 72.3 69.0 39.5 52.2 59.5 80.9 99.1 78.7 32.0 39.4 57.4 60.7 104.5 48.2 MRPS6 "C21orf101, MRP-S6, RPMS6" ENSG00000243927 "Mitochondrial ribosomal protein S6" P82932 21 34073224-34143034 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 281.0" "Cell type enhanced" "Detected in all" "Distal tubular cells: 747.4;Prostatic glandular cells: 568.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007861, HPA008163, HPA049676" Supported Supported Mitochondria NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 22: Epithelial cell types - Mixed function" Mitochondria "HPA007861: AB_2667920, HPA008163: AB_2667998, HPA049676: AB_2680846" "unprognostic (2.71e-2)" "unprognostic (4.85e-2)" "unprognostic (5.16e-3)" "unprognostic (4.01e-2)" "unprognostic (9.84e-3)" "unprognostic (3.72e-2)" "unprognostic (7.58e-3)" "unprognostic (1.80e-1)" "unprognostic (8.19e-2)" "unprognostic (2.28e-3)" "unprognostic (5.87e-2)" "unprognostic (2.52e-1)" "unprognostic (1.02e-3)" "unprognostic (9.37e-2)" "unprognostic (5.13e-2)" "unprognostic (5.51e-2)" "prognostic favorable (1.06e-5)" 67.6 72.5 53.9 33.8 56.1 15.6 46.1 53.0 118.1 42.7 85.9 81.6 22.7 37.1 50.7 31.3 37.9 24.8 57.3 55.4 60.8 281.0 50.6 37.8 46.7 54.7 56.5 41.7 22.2 24.2 39.4 51.8 55.6 33.1 36.5 25.6 26.2 41.6 96.1 53.5 39.0 36.7 58.9 28.6 51.3 44.8 63.3 38.3 97.5 76.8 49.8 50.6 33.7 57.8 70.8 56.6 211.0 77.2 74.1 72.9 71.4 79.5 185.4 68.7 70.0 181.8 134.9 105.6 51.7 104.0 92.8 28.7 124.6 106.0 73.4 193.5 65.4 89.6 34.3 47.8 35.4 45.2 31.7 35.0 107.8 127.2 116.5 104.2 47.4 45.2 116.5 28.0 140.7 66.0 73.4 104.1 136.9 135.4 122.1 99.6 37.4 101.5 307.4 60.4 187.5 50.0 84.5 46.2 103.6 112.6 87.3 58.7 24.3 62.8 36.6 115.4 46.3 132.5 125.8 96.3 204.2 118.4 62.8 67.0 53.8 60.4 90.3 53.7 66.6 74.9 67.0 81.4 56.1 48.4 83.8 87.3 46.8 115.7 57.5 101.4 74.0 79.6 53.9 56.1 53.0 118.1 55.4 60.8 54.7 56.5 55.6 58.9 63.3 57.8 45.1 22.4 40.9 32.3 83.9 266.8 229.8 226.6 126.9 40.5 78.9 125.9 59.8 28.6 75.8 252.0 10.4 195.2 103.0 56.3 747.4 41.1 83.1 85.2 88.6 58.0 91.5 45.4 25.7 36.7 237.0 111.7 32.6 58.6 137.7 184.5 25.7 95.7 126.5 8.4 57.9 211.0 75.3 36.4 207.6 73.1 28.0 104.8 101.4 32.8 164.0 37.9 108.1 45.2 6.2 52.8 138.5 102.7 102.0 568.4 61.0 159.2 66.0 26.5 118.3 26.9 104.8 90.4 136.5 71.0 331.0 182.4 124.2 49.8 99.9 335.6 MRPS7 "MRP-S, RP-S7, RPMS7" ENSG00000125445 "Mitochondrial ribosomal protein S7" Q9Y2R9 17 75261674-75266376 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 454.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022522, HPA023007" Supported Approved Mitochondria No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "HPA022522: AB_1854131, HPA023007: AB_1854132" "unprognostic (1.24e-1)" "unprognostic (4.74e-2)" "prognostic favorable (1.12e-4)" "unprognostic (5.82e-3)" "unprognostic (3.62e-2)" "unprognostic (5.05e-3)" "prognostic unfavorable (3.13e-4)" "unprognostic (1.32e-1)" "unprognostic (1.04e-1)" "unprognostic (4.95e-2)" "unprognostic (8.56e-3)" "unprognostic (1.03e-1)" "unprognostic (5.83e-2)" "unprognostic (1.03e-1)" "unprognostic (8.56e-2)" "unprognostic (1.76e-1)" "unprognostic (4.15e-1)" 44.3 58.4 55.5 38.1 55.9 32.9 41.2 60.0 61.9 28.7 59.0 49.9 48.9 28.3 24.4 58.5 39.2 27.1 129.0 55.1 59.3 66.1 64.6 32.4 41.3 57.2 57.5 29.2 39.0 76.6 36.0 40.8 57.6 34.1 48.2 47.3 41.1 35.7 201.3 32.6 40.0 33.8 57.8 39.5 47.5 29.9 59.8 33.6 35.9 212.3 43.6 42.6 35.0 56.3 113.8 188.6 78.8 57.6 63.9 35.7 139.4 73.3 60.9 137.4 101.1 209.8 93.5 96.4 66.4 79.8 91.4 104.5 122.3 135.8 82.2 50.8 173.5 131.8 133.6 201.3 62.5 134.3 69.6 60.0 131.8 108.6 109.6 69.2 177.3 117.8 130.1 93.3 91.1 203.5 151.8 104.7 85.4 157.7 176.2 100.7 229.5 145.2 128.4 124.6 135.8 122.8 93.8 249.9 150.0 83.9 188.4 108.7 72.2 124.0 125.3 68.2 155.7 97.9 61.5 106.6 89.5 88.3 96.9 43.2 155.1 48.2 115.7 161.6 124.2 140.2 112.0 126.0 172.0 128.1 128.6 120.7 11.0 130.5 138.5 164.9 141.6 236.0 55.5 55.9 60.0 61.9 55.1 59.3 57.2 57.5 57.6 57.8 59.8 56.3 44.1 51.3 48.3 12.1 69.3 39.5 75.1 148.1 37.0 65.8 56.5 63.0 77.8 70.1 74.3 57.0 98.0 192.9 63.3 94.1 230.9 112.9 139.2 50.9 43.2 55.6 47.5 61.4 11.8 104.1 175.3 50.2 55.5 43.5 39.3 68.6 45.3 91.7 148.8 47.1 14.0 84.3 77.3 60.0 35.6 454.3 48.4 52.6 42.7 3.7 107.0 85.6 73.2 9.5 11.3 89.8 69.3 39.9 87.7 85.3 129.2 219.3 81.0 114.4 59.2 40.8 73.0 60.5 68.5 68.5 41.9 137.9 53.8 110.0 133.8 77.4 MRPS9 "MRP-S9, RPMS9, S9mt" ENSG00000135972 "Mitochondrial ribosomal protein S9" P82933 2 105038069-105099960 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043476, HPA048479" Supported Supported Mitochondria No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "HPA043476: AB_2678498, HPA048479: AB_2680412" "unprognostic (8.10e-3)" "unprognostic (4.75e-3)" "unprognostic (3.69e-1)" "unprognostic (3.80e-3)" "unprognostic (5.25e-1)" "unprognostic (1.39e-1)" "prognostic unfavorable (4.43e-4)" "unprognostic (1.88e-1)" "unprognostic (1.16e-2)" "unprognostic (1.77e-1)" "unprognostic (1.13e-1)" "unprognostic (3.78e-1)" "unprognostic (2.62e-3)" "unprognostic (4.62e-2)" "unprognostic (5.28e-2)" "unprognostic (1.20e-1)" "unprognostic (1.12e-1)" 17.2 33.5 21.4 17.9 22.7 24.6 23.3 24.1 26.5 18.3 25.7 29.8 29.5 20.7 19.2 23.8 24.2 13.4 64.1 21.4 23.3 32.7 31.8 15.4 24.7 24.0 22.8 30.8 24.2 32.8 19.6 12.9 24.3 23.4 33.3 22.3 23.3 21.6 98.6 21.9 23.4 19.8 22.7 18.5 25.9 33.5 22.8 30.8 21.4 97.0 27.1 20.2 17.9 25.1 68.2 28.9 59.4 55.1 30.6 31.5 69.6 42.6 40.6 66.2 59.2 155.0 46.4 70.6 41.1 33.9 68.9 59.8 118.0 62.1 69.9 44.0 77.5 69.7 42.4 94.4 51.0 52.2 29.9 37.9 41.5 54.6 45.4 38.3 51.6 84.8 101.5 35.9 45.7 54.9 70.6 68.6 93.9 57.4 62.6 88.9 50.9 98.3 83.2 47.3 51.4 30.9 49.4 71.5 59.9 58.0 58.9 52.2 34.0 38.8 78.2 38.9 46.6 32.6 41.5 56.3 33.6 79.1 33.3 21.7 23.8 10.1 39.3 31.5 43.3 44.4 43.0 41.7 43.0 35.3 42.9 42.4 2.8 46.0 39.9 32.1 49.9 31.7 21.4 22.7 24.1 26.5 21.4 23.3 24.0 22.8 24.3 22.7 22.8 25.1 18.2 22.4 28.2 28.1 21.0 19.5 25.3 56.4 22.2 24.7 15.4 22.2 110.2 22.8 30.4 22.0 12.5 39.9 29.1 17.7 107.6 40.7 51.7 35.9 18.6 22.5 19.7 47.5 43.4 42.7 40.7 21.2 18.8 12.9 22.8 34.6 18.2 31.2 28.8 8.4 54.2 27.9 24.4 15.2 9.9 14.6 23.9 15.9 30.2 17.8 26.2 21.2 29.9 49.3 69.4 22.6 18.3 27.1 25.0 17.4 23.1 72.3 42.1 32.0 39.5 24.8 28.1 112.8 40.7 23.4 13.2 20.4 25.2 62.9 40.5 19.0 MT-CO1 "COI, COX1, MTCO1" ENSG00000198804 "Mitochondrially encoded cytochrome c oxidase I" P00395 MT 5904-7445 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Electron transport, Respiratory chain, Transport" Translocase "Deafness, Disease variant, Leber hereditary optic neuropathy, Non-syndromic deafness, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 222644.8;heart muscle: 255389.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 107039.5;Hepatocytes: 59794.3;Proximal enterocytes: 98329.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HeLa: 54167.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016241, HPA069328" Enhanced Supported Mitochondria NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "CAB016241: AB_2229888, HPA069328: AB_2686122" "unprognostic (4.39e-1)" "unprognostic (2.45e-1)" "unprognostic (1.39e-1)" "unprognostic (2.21e-1)" "unprognostic (1.59e-1)" "unprognostic (3.31e-1)" "prognostic favorable (2.29e-4)" "unprognostic (8.28e-2)" "unprognostic (1.01e-1)" "unprognostic (5.56e-3)" "unprognostic (1.20e-2)" "unprognostic (6.60e-2)" "unprognostic (2.83e-2)" "unprognostic (5.06e-3)" "unprognostic (4.50e-2)" "unprognostic (2.15e-2)" "unprognostic (2.44e-2)" 22006.8 46968.9 171347.0 8727.7 151652.8 11321.8 17952.5 132201.9 222644.8 10440.9 179120.2 42606.0 27505.7 11582.9 14226.0 20791.8 10700.5 11452.7 255389.3 151507.6 137459.2 63061.8 96575.5 12744.7 9111.4 176794.8 152802.2 8124.5 19467.4 41236.2 7420.2 10527.8 168465.9 12427.0 28389.7 12503.0 23260.1 17753.2 147209.5 26849.0 35366.3 13146.2 138626.1 16284.7 44852.9 10932.5 176888.2 7461.1 14056.3 184587.7 8381.2 17415.3 10559.7 131378.4 5837.6 8554.3 11384.1 12431.0 25510.2 11563.1 12037.2 12867.2 4284.9 3189.4 5257.4 10383.6 18320.5 15138.9 6040.7 9857.6 3118.2 21430.9 1326.6 11407.4 4515.1 7226.0 8040.6 9130.6 54167.9 19725.4 3521.2 5336.1 11055.5 13603.9 11589.8 3149.9 6917.5 14668.4 3902.1 8485.5 5916.3 10551.1 9525.6 14037.0 4378.4 23591.9 2905.0 7814.2 6900.5 5664.0 3401.6 9177.9 15910.6 15016.1 5414.7 7189.1 4466.7 17018.9 8305.7 13626.1 9809.7 17703.3 15637.8 12617.8 8438.9 12565.9 6642.1 4951.2 5072.9 3542.6 6235.7 13711.8 6294.4 5305.8 9759.2 3824.6 3085.1 4907.9 3420.5 5374.6 3047.3 3425.6 3444.6 5567.3 3080.8 3911.2 1900.4 3759.1 5775.1 4847.5 2947.7 3929.0 171347.0 151652.8 132201.9 222644.8 151507.6 137459.2 176794.8 152802.2 168465.9 138626.1 176888.2 131378.4 3924.0 2900.6 3897.1 0.0 13282.9 9769.7 9713.9 22625.0 20857.7 0.0 12033.2 11841.6 107039.5 30777.5 16135.4 19596.3 0.0 0.0 9288.4 40726.1 4255.4 7191.4 1555.3 13044.7 9033.9 7847.9 7514.7 45610.3 0.0 5089.4 0.0 6305.3 19235.7 25645.6 3832.6 20400.0 25951.4 59794.3 0.0 0.0 0.0 24302.1 19071.0 45533.4 7744.0 7398.4 11696.4 12124.7 6894.2 0.0 15180.0 0.0 8901.3 0.0 0.0 6410.5 23865.9 8490.1 13829.3 9441.3 98329.8 33652.6 10474.0 0.0 13614.6 11019.8 9403.5 12096.5 14338.7 27110.9 11475.1 0.0 11502.4 15179.6 27138.6 21770.7 MT-CYB "COB, CYTB, MTCYB, UQCR3" ENSG00000198727 "Mitochondrially encoded cytochrome b" P00156 MT 14747-15887 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Cardiomyopathy, Cataract, Deafness, Disease variant, Leber hereditary optic neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 130283.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 87067.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 14365.7;HeLa: 18945.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032215, HPA068400, HPA074796" Approved Supported Mitochondria NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "CAB032215: AB_2261378, HPA068400: AB_2685982, HPA074796: " "unprognostic (4.50e-1)" "unprognostic (2.56e-1)" "unprognostic (9.12e-2)" "unprognostic (3.88e-2)" "unprognostic (9.22e-2)" "unprognostic (3.50e-1)" "prognostic favorable (5.96e-4)" "unprognostic (1.63e-2)" "unprognostic (8.53e-2)" "unprognostic (1.49e-2)" "unprognostic (1.01e-3)" "unprognostic (6.09e-2)" "unprognostic (1.40e-1)" "unprognostic (7.90e-3)" "unprognostic (3.07e-1)" "unprognostic (4.09e-2)" "unprognostic (1.54e-2)" 17885.7 25075.8 39972.4 2636.6 41108.8 2926.5 15122.5 36592.4 54341.4 6621.5 47885.4 19364.4 8941.2 7119.4 6555.4 10592.2 7498.6 3433.7 130283.4 39044.7 39534.1 60620.7 59133.6 6549.1 2529.8 46506.6 40032.7 6068.7 15418.7 9106.2 11552.0 5320.4 42841.1 15142.5 8793.2 8513.5 12205.1 7331.2 52625.7 13392.0 17520.7 5804.8 34579.6 7362.7 25263.2 7372.2 41908.6 1737.2 9758.2 63751.5 3582.0 12844.4 7620.0 35340.5 2322.4 3039.1 3687.6 3950.3 14365.7 2287.8 2963.8 2587.3 1076.5 668.0 1136.3 3013.8 4943.2 5840.7 1240.7 3087.3 794.6 7063.3 556.2 3180.7 1613.0 2880.4 2458.9 3277.0 18945.0 5461.7 2697.8 1862.5 3828.3 4981.3 4631.2 1257.6 2679.7 4457.1 1715.5 2341.4 1709.0 3565.6 3417.2 6354.8 1735.3 3789.4 824.1 2230.7 2036.7 2028.2 1449.8 3681.4 5134.1 5275.9 1308.0 2302.7 1802.1 3352.1 2587.4 5497.2 4911.1 6332.5 5398.3 2302.7 2984.2 4256.3 2037.2 972.6 1390.1 2557.4 1385.7 2822.6 1485.0 8811.6 3750.4 4806.7 1834.1 1738.1 2355.1 2806.2 2123.9 2376.2 1485.5 3034.9 2241.0 2781.9 2755.9 1680.5 1944.8 1468.0 1511.0 1612.6 39972.4 41108.8 36592.4 54341.4 39044.7 39534.1 46506.6 40032.7 42841.1 34579.6 41908.6 35340.5 3091.7 1185.9 1390.0 0.0 5710.5 3319.9 7605.2 9945.0 8512.3 0.0 4026.8 5510.1 87067.0 11564.1 5338.9 7470.6 0.0 0.0 3723.1 10971.1 2163.9 2555.0 789.7 9063.7 5550.2 5673.6 2863.2 16130.5 0.0 3523.1 0.0 4692.6 4895.1 15794.2 1889.0 16261.2 9871.2 17132.6 0.0 0.0 0.0 9502.4 5486.9 14290.0 2254.1 3983.1 7943.2 4269.6 2612.9 0.0 4118.1 0.0 2612.8 0.0 0.0 2977.1 8823.6 5402.0 5725.9 4425.8 25108.7 14736.3 4210.2 0.0 5798.2 9579.6 5914.9 4807.6 4136.3 9142.3 3422.9 0.0 5502.2 11093.2 10319.6 9796.7 MT-ND4 "LHON, MTND4, NAD4, ND4" ENSG00000198886 "Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4" P03905 MT 10760-12137 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Dystonia, Leber hereditary optic neuropathy, MELAS syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 196536.0" "Cell type enriched" "Detected in many" 7 "Cardiomyocytes: 253563.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 13456.8" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HeLa: 41594.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053928 Approved Supported Mitochondria NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA053928: AB_2682313" "unprognostic (8.39e-2)" "unprognostic (1.83e-1)" "unprognostic (7.29e-2)" "unprognostic (9.54e-2)" "unprognostic (5.41e-2)" "unprognostic (3.78e-2)" "unprognostic (2.50e-3)" "unprognostic (8.16e-2)" "unprognostic (1.45e-1)" "prognostic favorable (1.76e-4)" "unprognostic (1.01e-2)" "unprognostic (7.23e-2)" "unprognostic (2.79e-2)" "unprognostic (1.53e-1)" "unprognostic (1.43e-1)" "unprognostic (3.14e-2)" "unprognostic (4.24e-2)" 23701.9 43566.1 86386.5 4193.8 83474.8 3652.7 19363.5 76852.9 119139.4 8711.6 100909.6 30312.4 11021.5 10764.3 6795.9 15885.7 10624.6 4622.9 196536.0 81116.7 85290.4 76204.1 101401.1 11855.8 3820.4 102081.7 90689.2 8957.6 21476.2 15709.9 12834.3 7692.4 97098.9 22214.5 15007.9 14112.1 17508.5 11691.2 61489.1 18268.8 25046.6 7116.7 75024.9 12782.7 39594.1 13571.1 91494.4 3233.7 14785.3 70605.7 4913.1 19417.4 10309.3 74806.7 4251.7 4285.9 5449.6 8075.1 12523.6 3123.1 3808.6 4184.0 1603.2 958.4 1834.2 6555.4 4688.4 7428.4 3608.7 3590.8 1396.3 7685.0 496.1 6777.9 1691.7 4330.2 2654.6 4592.7 41594.9 11166.3 1884.9 4672.8 5223.9 5330.2 7007.6 1403.3 4977.9 8925.4 2344.4 3683.1 3908.9 8930.2 3461.9 9508.0 1848.1 10481.0 1551.2 3650.3 2876.4 2481.0 1712.1 4518.2 6770.1 8938.3 1999.0 2694.8 2434.3 7967.3 4267.8 9600.3 5601.2 10888.7 6532.2 3851.7 3726.9 5232.7 3330.8 5307.6 2292.6 3407.7 2514.1 7881.4 2100.8 13456.8 3334.1 7103.1 1902.0 2192.8 2614.3 3555.5 2129.5 2285.7 1616.0 3624.4 2452.9 3095.1 2513.1 2106.5 2329.2 2112.6 1668.2 1840.0 86386.5 83474.8 76852.9 119139.4 81116.7 85290.4 102081.7 90689.2 97098.9 75024.9 91494.4 74806.7 3065.0 1269.2 1516.1 0.0 6183.3 4404.5 9073.3 7719.8 2713.0 0.0 6210.4 6965.6 253563.4 15377.3 4975.3 12806.1 0.0 0.0 4005.7 20185.0 2435.8 2924.2 1109.7 6731.7 4298.6 9316.2 5090.0 20898.0 0.0 4058.3 0.0 5843.3 5601.5 11920.4 2188.6 15486.9 13931.3 35046.7 0.0 0.0 0.0 14557.8 5771.7 22254.8 3452.7 5132.5 8834.9 4749.3 3799.3 0.0 6280.7 0.0 4212.2 0.0 0.0 3710.0 12363.2 5788.3 3409.4 5872.9 28978.7 17714.1 4527.9 0.0 6310.9 8264.3 7732.9 6461.4 6003.0 3008.8 4937.6 0.0 5125.3 7671.5 15595.2 11405.7 MTARC1 "FLJ22390, MARC1, MOSC1" ENSG00000186205 "Mitochondrial amidoxime reducing component 1" Q5VT66 1 220786913-220819659 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 192.3;breast: 86.2;liver: 84.5" "Group enriched" "Detected in some" 6 "Cytotrophoblasts: 109.8;Extravillous trophoblasts: 47.9;Syncytiotrophoblasts: 75.1" "Cancer enhanced" "Detected in many" "prostate cancer: 14.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "basophil: 30.2;classical monocyte: 33.6;eosinophil: 12.3;neutrophil: 42.8" "Group enriched" "Detected in many" 31 "granulocytes: 42.8;monocytes: 33.6" "Cell line enhanced" "Detected in many" "BEWO: 126.5;HeLa: 56.2;Hep G2: 67.6;NTERA-2: 57.8;OE19: 49.4" HPA028702 Approved Supported Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA028702: AB_10601135" "unprognostic (3.15e-2)" "unprognostic (1.27e-1)" "unprognostic (2.16e-2)" "unprognostic (5.04e-2)" "unprognostic (2.90e-1)" "unprognostic (2.31e-1)" "unprognostic (3.71e-3)" "unprognostic (1.39e-1)" "unprognostic (7.51e-2)" "unprognostic (7.71e-3)" "unprognostic (3.71e-1)" "unprognostic (4.30e-1)" "prognostic unfavorable (4.51e-4)" "unprognostic (3.85e-1)" "unprognostic (1.21e-1)" "unprognostic (1.24e-1)" "unprognostic (1.50e-1)" 192.3 7.4 9.4 6.8 10.5 17.9 86.2 9.8 13.2 7.9 7.9 18.9 7.6 2.8 14.0 7.6 6.2 4.1 8.4 10.0 11.7 10.2 84.5 9.3 2.8 10.1 11.8 5.5 9.6 5.4 7.0 16.0 9.6 36.2 17.3 5.7 27.2 13.5 11.0 3.6 9.7 4.0 9.1 10.2 9.3 1.4 14.3 1.6 53.5 9.2 2.1 8.8 5.0 8.5 15.0 7.8 5.9 0.2 1.3 0.3 126.5 1.4 1.2 0.8 1.5 45.4 1.0 0.1 5.3 1.6 0.1 0.1 28.3 2.9 2.1 0.2 25.7 0.1 56.2 67.6 2.7 0.3 0.5 4.5 1.3 0.2 0.0 0.2 1.1 0.1 4.3 0.3 1.1 14.7 0.1 31.9 57.8 49.4 23.8 0.1 0.0 0.3 7.1 17.4 16.4 36.1 8.1 11.4 0.2 16.4 38.5 34.7 0.4 0.1 12.6 0.1 0.1 0.2 0.1 0.1 0.2 0.0 1.1 30.2 33.6 12.3 0.1 2.5 0.0 0.4 0.0 0.0 1.2 0.2 0.1 0.0 42.8 0.0 1.3 0.3 0.0 9.2 9.4 10.5 9.8 13.2 10.0 11.7 10.1 11.8 9.6 9.1 14.3 8.5 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 109.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 47.9 0.7 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 75.1 0.0 0.0 0.0 0.0 MTCH2 SLC25A50 ENSG00000109919 "Mitochondrial carrier 2" Q9Y6C9 11 47617315-47642607 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 569.2;Proximal tubular cells: 508.1;Spermatocytes: 435.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038390 Approved Approved Mitochondria NA NA 14000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 18: U-2197 - ECM organization" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA038390: AB_10669723" "unprognostic (4.94e-2)" "unprognostic (3.29e-1)" "unprognostic (1.93e-2)" "unprognostic (1.43e-1)" "unprognostic (4.27e-1)" "unprognostic (7.63e-3)" "unprognostic (1.80e-1)" "unprognostic (7.03e-2)" "unprognostic (1.51e-1)" "unprognostic (1.53e-2)" "unprognostic (1.08e-1)" "unprognostic (1.14e-1)" "prognostic favorable (9.05e-6)" "unprognostic (1.12e-2)" "unprognostic (8.75e-2)" "unprognostic (2.25e-1)" "unprognostic (1.77e-1)" 28.8 40.3 13.2 14.1 14.1 12.6 25.3 14.3 15.7 20.5 12.7 41.7 38.9 26.8 19.4 50.3 18.9 11.9 41.0 13.8 15.1 57.3 115.3 20.0 14.7 13.3 14.0 13.6 22.6 21.2 18.5 9.9 13.7 18.3 32.7 16.2 29.8 11.9 81.8 28.7 37.6 21.4 12.8 19.6 22.6 69.8 14.7 14.6 21.6 47.5 23.0 23.2 26.1 14.9 47.8 51.2 42.9 57.9 49.7 45.8 31.6 50.5 46.1 66.7 62.6 40.9 47.2 65.4 26.8 62.3 71.7 58.5 77.7 66.4 80.9 33.0 73.4 37.5 69.3 82.5 68.2 79.1 36.1 52.1 51.5 44.3 65.8 38.6 61.1 55.1 70.9 38.0 82.9 69.3 61.1 59.5 46.4 92.4 77.0 56.1 65.4 47.0 78.5 60.6 51.0 35.7 69.1 68.8 37.1 40.3 99.2 36.4 51.2 60.9 52.9 102.4 65.8 40.5 49.3 73.2 50.4 67.7 55.7 13.3 33.8 14.1 20.3 37.6 19.6 25.1 17.7 19.2 44.0 19.5 15.1 17.6 3.2 22.2 31.5 28.9 24.0 34.1 13.2 14.1 14.3 15.7 13.8 15.1 13.3 14.0 13.7 12.8 14.7 14.9 28.4 22.4 35.9 54.9 39.2 47.0 56.0 169.3 44.9 0.0 50.7 41.3 67.8 71.4 84.0 53.3 0.0 82.8 41.2 98.1 181.9 153.3 569.2 48.8 37.5 31.6 79.8 74.6 47.0 109.4 119.1 40.0 46.4 40.1 37.3 29.3 33.2 289.4 164.2 0.0 50.9 97.0 150.5 65.7 40.3 166.5 28.9 67.5 81.8 22.5 103.9 0.0 30.9 58.8 58.6 93.0 69.7 58.3 70.9 84.9 213.3 508.1 79.0 0.0 32.9 30.0 141.3 435.4 104.4 129.8 54.1 127.8 34.5 74.4 165.5 65.2 MTERF1 MTERF ENSG00000127989 "Mitochondrial transcription termination factor 1" Q99551 7 91692008-91880702 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Transcription termination" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044894, HPA069560" Uncertain Supported Mitochondria NA NA "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA044894: AB_10966284, HPA069560: AB_2686154" "unprognostic (5.57e-2)" "unprognostic (7.31e-2)" "unprognostic (2.15e-2)" "unprognostic (1.50e-2)" "unprognostic (2.55e-1)" "unprognostic (1.81e-1)" "unprognostic (3.15e-3)" "unprognostic (1.25e-2)" "unprognostic (1.46e-3)" "unprognostic (7.62e-2)" "unprognostic (2.67e-1)" "unprognostic (5.19e-2)" "unprognostic (3.21e-2)" "unprognostic (1.14e-1)" "unprognostic (3.90e-2)" "unprognostic (2.67e-1)" "unprognostic (2.22e-3)" 4.7 6.1 4.0 7.9 5.1 10.1 9.2 4.7 5.1 5.5 4.1 7.6 7.0 7.0 7.6 7.3 5.9 5.4 5.9 4.2 5.2 8.4 11.3 5.2 14.0 4.5 4.1 8.3 5.9 6.5 5.0 7.1 5.0 6.1 7.8 6.5 7.5 5.9 5.0 6.3 6.8 6.1 4.1 9.7 8.1 6.6 4.8 11.4 7.5 8.9 13.3 5.7 5.8 6.8 17.3 15.0 13.3 9.0 12.2 13.9 12.6 14.2 14.3 15.8 19.6 16.9 17.7 36.8 11.9 11.0 21.3 15.2 21.3 13.4 23.9 1.9 14.5 16.1 17.2 13.4 11.6 29.3 15.7 17.2 16.3 15.8 18.5 11.4 12.9 8.1 31.2 15.0 18.1 22.2 31.5 27.0 22.2 20.1 16.5 9.3 19.2 23.4 15.8 17.5 12.8 23.4 13.9 30.1 29.0 24.3 10.9 19.4 9.5 18.4 22.2 25.4 14.9 19.4 21.9 48.7 13.0 9.4 26.9 46.0 12.9 18.5 14.6 11.2 18.5 22.0 19.2 21.9 14.1 23.9 26.1 20.7 6.2 16.1 13.5 11.2 20.1 15.1 4.0 5.1 4.7 5.1 4.2 5.2 4.5 4.1 5.0 4.1 4.8 6.8 5.5 9.6 10.6 6.2 10.5 0.0 3.9 0.0 14.8 0.0 5.3 6.7 5.3 5.7 2.5 3.7 0.0 9.3 8.0 3.4 5.9 5.9 1.5 4.5 7.0 4.9 1.2 8.2 7.9 5.2 6.3 6.2 7.7 4.0 5.1 8.3 6.4 9.6 5.1 0.0 7.2 2.6 0.0 6.0 0.0 2.1 6.8 5.9 0.0 5.6 7.1 0.0 10.3 8.0 15.2 4.1 3.1 7.2 12.6 3.9 7.2 8.2 1.5 0.0 13.1 5.0 5.3 14.0 10.5 6.3 0.0 4.5 8.0 8.5 4.1 2.7 MTFP1 "HSPC242, MTP18" ENSG00000242114 "Mitochondrial fission process 1" Q9UDX5 22 30425623-30429054 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 69.7;Exocrine glandular cells: 52.2;Plasma cells: 43.5;Undifferentiated cells: 45.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077396 Approved Mitochondria NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA077396: AB_2686837" "unprognostic (2.19e-2)" "unprognostic (1.18e-1)" "unprognostic (3.12e-1)" "unprognostic (6.20e-2)" "unprognostic (4.86e-2)" "unprognostic (1.72e-3)" "unprognostic (1.52e-3)" "unprognostic (8.98e-2)" "unprognostic (2.07e-1)" "unprognostic (1.65e-1)" "unprognostic (6.37e-3)" "unprognostic (1.54e-1)" "unprognostic (1.49e-1)" "unprognostic (6.40e-2)" "unprognostic (3.06e-2)" "unprognostic (3.84e-1)" "unprognostic (1.66e-2)" 12.9 15.6 8.7 10.1 9.1 14.2 11.6 11.1 9.9 8.3 16.8 17.1 16.8 3.8 15.1 19.8 3.4 8.1 26.2 9.0 10.2 38.9 31.9 11.9 16.5 9.9 9.7 5.0 19.0 21.8 8.1 11.4 9.3 13.5 12.9 23.4 10.1 4.9 26.2 7.6 13.4 4.7 9.1 20.9 19.7 4.0 10.8 7.8 8.5 19.3 14.8 13.7 7.6 8.6 91.9 69.5 23.8 37.1 5.1 4.1 27.2 8.6 8.2 51.3 78.5 33.6 52.4 99.5 25.3 6.0 41.3 46.5 74.0 77.6 34.7 56.2 96.5 26.7 38.6 64.9 14.8 66.7 52.7 7.6 25.7 31.4 47.4 15.7 43.5 45.1 51.2 35.5 16.3 109.5 63.3 71.8 41.5 82.9 73.2 85.6 23.1 87.3 61.0 24.8 40.6 44.5 19.9 90.6 35.6 16.9 28.8 31.4 18.4 55.9 72.4 27.6 26.3 17.8 15.5 86.1 22.4 75.9 23.7 0.2 14.3 0.1 49.2 17.1 65.5 34.0 39.6 42.3 20.3 23.7 41.7 48.2 1.8 14.0 11.6 10.5 36.0 25.6 8.7 9.1 11.1 9.9 9.0 10.2 9.9 9.7 9.3 9.1 10.8 8.6 5.3 6.4 3.0 3.9 21.7 5.6 1.8 12.0 6.2 0.0 10.1 3.7 4.4 7.2 6.7 3.7 0.0 13.4 14.8 33.2 15.6 69.7 0.1 1.9 1.4 5.8 8.4 9.2 0.8 52.2 30.4 2.5 20.9 2.6 9.5 0.4 5.0 11.1 17.6 0.0 2.7 28.1 2.0 10.3 9.6 0.2 0.6 6.4 3.6 1.0 36.6 0.0 10.3 0.5 0.3 40.3 13.8 0.4 43.5 3.5 28.3 11.8 1.9 0.0 0.0 1.5 5.1 0.6 2.1 16.5 5.5 16.8 29.6 0.7 45.3 2.2 MTG1 GTPBP7 ENSG00000148824 "Mitochondrial ribosome associated GTPase 1" Q9BT17 10 133394094-133422520 "Predicted intracellular proteins" "Translation regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 43.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037826, HPA037827" Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA037826: AB_2675692, HPA037827: AB_10670959" "unprognostic (2.94e-2)" "unprognostic (8.08e-2)" "unprognostic (5.90e-3)" "unprognostic (1.03e-1)" "unprognostic (1.48e-1)" "unprognostic (1.29e-2)" "unprognostic (5.85e-2)" "unprognostic (6.20e-2)" "unprognostic (1.32e-1)" "unprognostic (2.21e-1)" "prognostic favorable (5.08e-4)" "unprognostic (4.63e-3)" "prognostic unfavorable (6.79e-7)" "unprognostic (3.88e-2)" "unprognostic (5.96e-2)" "unprognostic (5.19e-2)" "prognostic favorable (1.03e-5)" 15.1 28.1 10.0 13.6 9.9 12.5 16.3 11.0 12.2 17.0 11.4 16.0 19.7 15.2 2.8 21.4 15.0 8.4 15.0 9.7 9.6 27.1 48.4 13.0 16.2 10.8 9.9 17.2 19.7 17.6 16.2 11.2 10.2 19.3 11.2 3.4 16.3 10.4 18.5 17.7 18.9 10.1 9.3 26.1 18.4 31.2 10.4 12.7 18.0 13.0 14.1 15.4 15.4 9.9 42.5 43.3 28.3 63.4 17.0 12.5 42.0 24.2 20.8 38.5 31.4 55.0 25.8 31.2 36.2 20.5 16.3 33.5 30.6 43.2 17.4 29.8 37.7 30.5 23.5 52.1 40.2 20.6 30.4 31.5 22.9 37.3 58.6 27.7 56.5 27.9 26.2 28.0 30.6 47.4 20.2 28.9 39.3 45.2 14.4 29.6 28.0 7.1 34.6 29.6 10.7 37.9 36.4 32.1 51.4 15.8 28.2 29.6 37.1 14.2 29.2 14.6 26.1 13.5 8.3 43.3 25.2 18.3 19.8 0.5 21.5 23.0 26.9 35.5 27.7 41.5 23.8 22.7 20.3 48.8 18.6 19.2 3.1 47.5 42.9 42.8 27.5 20.3 10.0 9.9 11.0 12.2 9.7 9.6 10.8 9.9 10.2 9.3 10.4 9.9 4.5 9.6 3.6 30.7 27.1 4.2 5.9 8.8 33.0 0.0 6.1 5.3 1.6 8.6 5.9 3.7 0.0 9.4 8.1 8.4 5.9 13.5 2.2 5.9 9.9 7.7 12.6 26.1 25.1 9.6 7.3 9.0 43.8 5.9 6.3 10.8 7.5 5.5 5.4 0.0 31.8 7.5 4.1 6.3 4.7 5.4 9.0 7.1 5.4 21.5 8.1 0.0 12.3 29.7 33.9 10.4 9.2 4.9 37.5 7.2 12.5 6.9 6.1 0.0 13.1 6.1 6.0 9.0 9.3 32.9 3.4 6.7 16.6 6.7 10.1 7.4 MTHFD1L "DKFZP586G1517, FLJ21145, FTHFSDC1" ENSG00000120254 "Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like" Q6UB35 6 150865679-151101887 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "One-carbon metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 84.0;Extravillous trophoblasts: 166.5;Granulosa cells: 86.9;Microglial cells: 126.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 4 "dendritic cells: 1.1;T-cells: 1.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015006, HPA029040, HPA029041, HPA050052, HPA074911" Approved Enhanced Mitochondria NA NA 89000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Mitochondria "HPA015006: AB_1854178, HPA029040: AB_2672879, HPA029041: AB_2672880, HPA050052: AB_2680998, HPA074911: AB_2686723" "unprognostic (3.66e-2)" "prognostic unfavorable (1.68e-5)" "unprognostic (1.02e-1)" "prognostic unfavorable (7.28e-4)" "unprognostic (3.25e-1)" "prognostic unfavorable (5.10e-4)" "prognostic unfavorable (8.33e-5)" "unprognostic (6.35e-3)" "unprognostic (2.45e-1)" "unprognostic (1.44e-1)" "unprognostic (1.02e-1)" "unprognostic (1.32e-1)" "unprognostic (1.11e-2)" "unprognostic (2.93e-2)" "unprognostic (3.51e-1)" "unprognostic (2.91e-1)" "prognostic unfavorable (8.69e-5)" 12.5 12.2 7.1 11.4 6.7 13.2 7.9 25.1 7.4 7.1 8.3 7.4 3.2 8.4 6.2 6.7 7.1 5.9 11.5 6.4 9.8 12.7 5.6 19.5 11.1 11.5 10.1 14.6 10.7 6.8 9.2 14.3 11.0 5.5 7.9 7.5 3.2 7.0 1.3 6.0 5.2 10.0 11.6 9.2 6.0 9.9 8.4 8.6 10.9 0.5 10.8 12.8 4.2 15.4 40.6 35.1 44.9 110.0 11.5 40.0 108.4 63.0 68.3 62.1 75.7 71.8 37.4 152.3 41.1 96.9 36.8 42.7 72.4 61.8 76.8 63.4 65.3 62.7 60.4 66.1 72.4 115.7 9.8 47.7 76.9 60.6 109.8 55.5 105.5 81.6 150.9 76.2 65.0 86.1 57.1 23.9 45.5 40.7 32.1 67.2 33.2 67.1 42.1 19.6 44.1 32.5 83.9 36.7 53.0 40.6 11.5 79.5 80.6 41.4 90.6 91.9 90.5 62.3 63.5 154.0 68.8 105.7 54.0 0.0 0.2 0.0 0.2 0.3 0.4 0.2 0.6 0.7 1.1 0.3 0.5 0.6 0.0 0.3 0.3 0.5 1.8 0.2 7.1 6.7 25.1 7.4 6.4 9.8 11.5 10.1 11.0 11.6 8.4 15.4 6.9 0.0 1.7 47.7 6.9 6.5 8.0 15.7 1.8 0.0 3.3 4.1 2.4 1.5 9.8 14.7 0.0 25.8 1.4 2.6 7.9 9.0 44.9 11.3 18.4 10.7 1.2 5.0 84.0 18.1 166.5 14.4 8.2 22.2 0.0 86.9 6.1 1.7 24.9 0.0 73.8 3.0 46.8 3.0 13.3 6.2 0.6 13.8 35.6 126.5 2.4 0.0 2.1 60.8 59.3 19.2 1.4 7.9 14.0 31.3 0.9 15.2 5.3 0.0 0.0 8.7 13.1 0.5 6.8 2.3 3.4 73.6 4.0 42.9 4.0 35.1 MTHFD2 ENSG00000065911 "Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase" P13995 2 74186172-74217565 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "One-carbon metabolism" "Hydrolase, Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 243.6;monocytes: 184.1;Smooth muscle cells: 239.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003684, HPA049657" Approved Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 52: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria "CAB003684: AB_425867, HPA049657: AB_2680842" "unprognostic (1.82e-3)" "unprognostic (4.60e-2)" "unprognostic (8.12e-2)" "prognostic unfavorable (2.07e-5)" "prognostic favorable (1.01e-4)" "unprognostic (3.10e-3)" "unprognostic (2.24e-3)" "unprognostic (4.75e-3)" "unprognostic (2.64e-2)" "unprognostic (3.96e-2)" "unprognostic (3.76e-3)" "unprognostic (3.57e-3)" "prognostic unfavorable (1.11e-16)" "unprognostic (3.66e-2)" "unprognostic (6.52e-2)" "unprognostic (9.07e-2)" "unprognostic (2.34e-3)" 40.0 12.3 11.2 54.5 13.0 25.8 34.8 12.7 14.7 28.5 11.2 30.6 18.6 21.5 14.5 23.0 34.2 20.1 19.6 10.0 16.6 19.6 7.3 23.0 45.6 16.6 15.8 11.7 65.9 9.8 18.0 17.7 17.1 16.3 33.7 2.9 17.7 16.7 36.7 11.8 16.0 27.3 14.8 19.0 36.1 17.7 13.1 28.5 18.5 55.3 57.8 48.0 20.5 15.7 197.4 107.8 89.2 235.6 90.0 113.9 186.1 286.2 185.2 156.2 216.7 242.8 81.8 391.0 65.4 154.2 167.5 70.7 296.7 142.0 314.9 248.9 100.9 424.6 55.4 181.9 319.8 360.1 234.8 202.9 423.4 188.5 794.4 74.8 99.0 636.5 192.2 548.0 157.5 159.6 209.5 261.0 161.1 293.3 95.8 222.6 266.3 339.4 72.0 80.8 198.2 143.8 97.4 238.3 549.7 56.9 208.5 324.4 52.9 39.1 359.9 97.7 286.5 484.5 257.6 379.2 111.4 304.1 132.5 43.9 24.0 31.1 8.5 56.6 13.0 13.4 15.2 10.1 34.9 12.2 11.5 7.9 3.2 29.3 57.0 13.0 36.8 22.0 11.2 13.0 12.7 14.7 10.0 16.6 16.6 15.8 17.1 14.8 13.1 15.7 19.7 16.0 20.2 0.3 49.7 89.3 58.8 54.1 27.3 0.0 53.2 38.0 11.5 4.3 28.2 1.8 0.0 31.5 48.2 19.9 3.9 55.7 3.9 9.7 104.7 35.1 19.1 104.1 1.0 107.9 56.9 45.6 68.8 21.7 53.3 8.7 19.2 0.8 66.2 0.0 3.7 64.0 38.7 61.6 243.6 3.8 22.7 100.6 71.2 12.2 184.1 0.0 27.8 6.6 1.1 81.2 7.5 21.1 141.2 95.7 3.3 3.3 8.5 0.0 138.1 126.3 239.0 36.5 54.9 42.0 74.6 14.0 71.4 21.6 34.0 64.2 MTIF2 IF-2mt ENSG00000085760 "Mitochondrial translational initiation factor 2" P46199 2 55236595-55269347 "Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 80.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006021, HPA061422" Approved Enhanced Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA006021: AB_2147687, HPA061422: AB_2684514" "unprognostic (2.91e-2)" "unprognostic (9.58e-2)" "unprognostic (1.52e-2)" "unprognostic (1.87e-3)" "unprognostic (8.86e-2)" "unprognostic (5.57e-2)" "unprognostic (9.76e-3)" "unprognostic (1.88e-1)" "unprognostic (6.85e-3)" "unprognostic (3.01e-2)" "unprognostic (6.58e-3)" "unprognostic (1.76e-1)" "unprognostic (3.98e-2)" "unprognostic (2.54e-2)" "unprognostic (1.66e-1)" "unprognostic (9.45e-3)" "unprognostic (1.33e-1)" 17.5 18.2 14.8 16.7 16.6 14.2 19.6 17.0 18.0 14.4 19.1 27.7 27.2 10.8 17.8 18.7 13.0 11.6 31.9 15.0 17.4 24.8 33.0 12.3 20.6 16.8 16.1 11.4 26.7 24.2 10.9 13.4 17.0 14.4 31.5 15.5 18.5 14.0 44.2 16.1 22.0 12.4 16.4 17.4 20.7 12.2 16.8 16.8 20.5 48.8 20.3 15.0 13.2 18.1 42.4 39.8 23.2 40.2 27.8 37.7 53.1 37.8 29.9 35.5 30.9 48.0 39.8 69.1 69.6 34.5 39.7 36.7 55.2 54.5 58.3 77.1 42.6 63.3 30.9 89.4 53.4 101.6 36.4 41.7 54.9 49.1 101.9 31.4 29.1 37.8 114.4 38.4 37.0 35.2 31.5 68.2 49.3 52.2 48.5 32.7 74.3 67.1 34.4 36.8 41.3 26.2 33.7 54.8 71.0 27.8 28.9 33.6 28.5 37.0 42.5 44.6 62.8 71.3 68.3 18.8 39.3 74.3 29.7 5.6 10.3 9.7 9.0 12.7 11.7 7.5 9.2 8.6 13.5 9.5 11.2 11.5 4.0 16.7 10.8 6.6 12.2 6.8 14.8 16.6 17.0 18.0 15.0 17.4 16.8 16.1 17.0 16.4 16.8 18.1 10.9 22.4 23.6 9.8 16.6 7.6 19.1 18.8 13.6 0.0 15.5 14.2 80.7 22.8 16.9 7.3 0.0 32.1 22.2 18.7 29.4 33.6 16.9 24.0 17.6 13.5 19.2 22.1 8.9 33.5 31.1 14.0 17.3 15.6 21.5 26.7 10.4 29.9 23.8 0.0 9.7 19.3 18.3 25.1 7.0 18.2 9.0 19.0 8.8 12.2 35.5 0.0 21.6 8.5 13.6 29.8 15.3 10.5 21.5 11.8 26.3 25.7 22.5 0.0 6.6 14.0 20.6 30.1 17.8 20.3 7.4 16.3 13.3 29.0 33.3 15.1 MTPAP "FLJ10486, PAPD1, SPAX4, TENT6" ENSG00000107951 "Mitochondrial poly(A) polymerase" Q9NVV4 10 30309801-30374448 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "mRNA processing, Transcription" "Nucleotidyltransferase, RNA-binding, Transferase" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 36.8" "Cell type enriched" "Detected in many" 7 "Early spermatids: 240.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038620, HPA058232" Approved Supported Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" Mitochondria "HPA038620: AB_10673015, HPA058232: AB_2683646" "unprognostic (2.76e-2)" "unprognostic (2.04e-1)" "unprognostic (1.73e-1)" "unprognostic (3.43e-3)" "unprognostic (3.05e-2)" "unprognostic (1.01e-1)" "prognostic unfavorable (4.20e-6)" "unprognostic (1.16e-1)" "unprognostic (2.04e-1)" "unprognostic (4.78e-2)" "unprognostic (1.77e-1)" "unprognostic (3.56e-2)" "unprognostic (9.02e-2)" "unprognostic (6.28e-3)" "unprognostic (3.77e-1)" "unprognostic (1.14e-2)" "unprognostic (4.39e-2)" 8.9 7.4 4.9 10.3 4.8 36.8 9.7 12.6 6.7 6.1 3.1 9.6 10.6 9.0 6.2 8.3 6.6 5.2 8.8 4.8 4.3 9.6 10.6 6.3 10.7 3.4 3.5 8.2 10.0 8.4 2.7 9.6 3.9 7.2 11.0 7.1 8.0 4.9 13.2 8.4 9.0 9.1 3.2 9.3 7.1 5.1 3.6 9.2 10.2 12.0 10.3 8.1 5.2 6.2 26.0 25.3 15.8 23.0 15.2 14.2 20.6 17.6 6.2 17.7 18.4 27.0 35.4 36.9 12.3 11.7 16.3 29.7 31.1 20.7 21.6 18.7 24.0 37.3 23.7 27.5 16.0 24.6 28.2 14.3 19.0 19.9 11.7 9.8 19.6 34.0 41.2 28.1 13.5 21.8 29.8 21.8 10.8 19.5 13.3 29.6 27.9 34.4 16.2 17.1 25.9 20.8 16.0 16.4 24.7 14.8 15.8 15.6 18.7 18.4 23.8 26.0 19.8 6.2 16.3 50.8 15.9 44.5 6.6 27.4 25.2 27.3 21.7 35.0 23.0 20.8 20.4 21.1 33.0 17.1 21.6 22.0 4.2 25.1 27.9 17.3 23.1 13.1 4.9 4.8 12.6 6.7 4.8 4.3 3.4 3.5 3.9 3.2 3.6 6.2 12.2 9.6 7.4 9.1 11.2 25.2 13.9 7.4 4.6 0.0 9.8 9.8 16.7 15.7 9.2 3.7 0.0 13.1 13.9 8.1 19.6 9.6 240.7 9.9 14.8 12.9 4.2 16.6 12.7 9.1 12.0 12.7 7.7 12.5 5.1 18.8 12.5 14.6 14.7 0.0 14.5 15.6 6.1 15.8 13.6 34.3 12.2 10.8 8.8 8.4 14.8 0.0 5.2 4.5 14.4 8.9 5.2 16.6 5.3 14.1 8.7 14.2 8.6 0.0 13.1 14.7 10.8 25.3 19.5 11.4 24.9 11.5 8.8 12.6 18.4 16.6 MTX1 "MTX, MTXN" ENSG00000173171 "Metaxin 1" Q13505 1 155208695-155213824 "Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 7 "Early spermatids: 601.3;Late spermatids: 1473.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011543 Uncertain Approved Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 43: Testis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "HPA011543: AB_1853824" "unprognostic (2.57e-1)" "unprognostic (9.51e-3)" "unprognostic (3.27e-1)" "unprognostic (5.98e-3)" "unprognostic (1.60e-1)" "unprognostic (2.62e-2)" "unprognostic (1.12e-2)" "unprognostic (1.80e-1)" "unprognostic (8.38e-2)" "unprognostic (1.28e-2)" "unprognostic (1.71e-1)" "unprognostic (6.78e-2)" "prognostic unfavorable (3.39e-4)" "unprognostic (1.30e-2)" "unprognostic (1.70e-1)" "unprognostic (1.37e-1)" "unprognostic (1.96e-2)" 29.3 33.2 23.9 16.1 24.5 39.1 28.2 25.2 29.2 22.3 29.2 25.9 18.9 25.3 17.8 33.0 31.0 13.1 22.1 23.2 24.2 34.1 44.8 22.9 19.6 24.8 24.7 17.6 27.7 37.7 20.3 20.8 24.5 22.1 18.8 3.7 31.6 21.7 17.5 25.5 23.0 18.6 24.7 29.3 28.1 90.3 24.8 20.9 24.4 16.7 21.2 20.7 21.2 25.3 54.3 87.6 27.3 39.3 49.9 44.8 86.4 27.4 55.0 79.4 55.1 109.5 88.2 44.3 88.2 63.4 25.2 52.8 40.6 77.4 28.8 32.9 95.4 28.3 64.0 107.1 78.8 52.5 38.0 57.5 71.2 82.2 54.9 30.4 71.2 64.4 58.1 21.5 47.9 131.7 59.6 65.9 54.7 76.5 100.2 48.3 17.2 105.4 73.1 46.2 44.5 55.3 34.0 106.3 31.0 41.6 86.2 84.1 30.0 37.8 42.6 25.4 46.9 41.1 37.3 46.2 50.1 26.8 41.3 32.8 69.0 17.4 24.2 38.3 23.2 41.6 29.6 25.7 60.8 37.7 29.3 26.5 114.2 34.6 22.2 32.9 39.0 40.6 23.9 24.5 25.2 29.2 23.2 24.2 24.8 24.7 24.5 24.7 24.8 25.3 26.0 9.6 17.0 4.9 28.9 20.3 42.0 91.3 26.7 0.0 41.8 42.4 1.1 27.1 45.1 35.0 0.0 107.5 17.1 36.5 97.8 80.1 601.3 56.6 35.1 24.7 19.8 14.7 2.8 84.7 130.7 33.6 40.8 30.1 26.6 42.2 23.9 54.4 97.3 0.0 3.6 42.3 54.9 37.1 23.3 1473.9 43.2 38.9 49.8 1.0 65.1 0.0 37.0 3.0 4.8 72.7 48.4 39.5 39.3 41.6 44.3 144.6 61.2 0.0 46.0 29.2 58.4 105.2 52.9 34.9 21.0 88.7 22.5 43.9 54.6 42.6 MTX3 ENSG00000177034 "Metaxin 3" Q5HYI7 5 79976716-79991262 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047858, HPA062061" Approved Approved Mitochondria NA NA "Cluster 30: Non-specific - Translation" "Cluster 51: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" Mitochondria "HPA047858: AB_2680185, HPA062061: AB_2684672" "unprognostic (2.56e-2)" "unprognostic (2.32e-1)" "unprognostic (2.47e-2)" "unprognostic (4.21e-2)" "unprognostic (4.59e-1)" "unprognostic (1.88e-2)" "prognostic unfavorable (5.08e-5)" "unprognostic (4.02e-2)" "unprognostic (2.65e-2)" "prognostic unfavorable (2.54e-4)" "unprognostic (8.58e-2)" "unprognostic (8.46e-2)" "unprognostic (5.08e-2)" "unprognostic (1.01e-2)" "unprognostic (1.11e-2)" "unprognostic (3.09e-2)" "unprognostic (2.28e-1)" 6.8 10.0 5.9 6.2 6.8 6.4 8.1 6.0 7.1 8.2 4.8 8.6 4.4 9.2 6.7 7.9 8.3 3.9 7.7 6.9 5.9 6.9 5.6 5.5 8.3 6.2 6.1 12.5 7.2 11.8 7.3 4.5 6.7 7.8 4.9 11.9 8.3 6.8 8.7 7.6 9.6 6.1 5.4 8.3 7.4 5.1 6.8 3.8 8.8 5.5 7.9 7.9 7.6 6.2 8.6 4.9 13.1 7.1 6.3 11.3 3.3 8.2 5.9 6.6 7.3 2.1 9.1 13.6 2.4 7.7 11.0 9.9 0.0 18.1 12.4 3.6 8.0 5.7 14.7 6.8 11.8 0.0 6.7 9.0 18.0 11.4 20.1 9.3 4.6 0.0 3.0 7.5 11.3 9.2 0.0 0.1 13.4 2.8 5.1 0.0 19.7 5.8 6.0 9.7 17.1 13.2 10.8 7.4 15.9 10.1 12.1 9.7 5.3 11.9 9.7 9.2 18.0 10.5 10.8 11.9 17.8 0.0 15.0 0.3 0.2 0.2 0.6 0.2 0.4 0.8 0.6 0.5 0.1 0.5 0.8 0.6 0.2 0.4 0.1 0.2 0.4 0.2 5.9 6.8 6.0 7.1 6.9 5.9 6.2 6.1 6.7 5.4 6.8 6.2 7.6 28.9 5.3 18.9 8.4 1.5 4.9 2.7 9.6 0.0 9.8 6.7 9.4 15.7 8.0 12.9 0.0 5.1 6.2 2.5 5.9 3.9 2.7 9.2 16.4 7.2 0.0 3.8 27.1 2.5 3.2 9.9 5.1 8.6 1.3 20.6 10.8 7.9 3.2 0.0 24.5 4.4 4.1 3.5 1.7 4.1 12.8 3.4 0.0 5.6 2.8 0.0 5.2 23.6 25.0 5.3 5.3 12.4 5.1 8.7 3.9 8.6 12.5 0.0 13.1 13.4 9.8 8.8 7.5 11.5 3.4 1.8 8.1 15.5 6.0 5.8 MXRA5 DKFZp564I1922 ENSG00000101825 "Matrix remodeling associated 5" Q9NR99 X 3308565-3346652 "Cancer-related genes, Disease related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 35.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 38.5;Collecting duct cells: 31.3;Exocrine glandular cells: 60.7;Fibroblasts: 56.0;Pancreatic endocrine cells: 42.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 31.4;BJ hTERT+: 125.8;fHDF/TERT166: 59.8;HaCaT: 52.4;HSkMC: 24.7" "Low region specificity" "Detected in all" "HPA000508, HPA076518" Uncertain Uncertain Mitochondria "Secreted to extracellular matrix" NA NA 2600000 "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Mitochondria "HPA000508: AB_2147995, HPA076518: " "unprognostic (7.51e-2)" "unprognostic (6.45e-2)" "unprognostic (8.00e-2)" "unprognostic (2.51e-2)" "prognostic unfavorable (1.81e-4)" "unprognostic (7.05e-2)" "unprognostic (7.25e-2)" "unprognostic (1.35e-2)" "unprognostic (1.13e-1)" "unprognostic (2.53e-2)" "unprognostic (6.32e-3)" "unprognostic (1.38e-1)" "unprognostic (1.65e-2)" "unprognostic (1.58e-1)" "unprognostic (1.90e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (8.94e-4)" 12.0 10.3 0.2 9.4 0.3 0.0 13.5 0.0 0.4 35.0 0.0 7.5 4.4 6.8 2.7 9.4 3.0 8.0 11.1 0.2 0.1 5.3 4.5 5.3 1.6 0.3 0.3 2.9 16.1 1.7 0.9 5.8 0.2 7.3 10.4 0.0 6.1 10.4 1.5 29.6 4.6 15.9 0.5 3.6 10.3 0.1 1.2 5.7 9.8 5.1 3.7 19.9 7.2 0.1 0.0 0.0 0.8 0.0 0.2 31.4 0.0 19.6 125.8 0.2 0.2 0.0 0.6 0.0 1.7 59.8 0.2 52.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 24.7 5.9 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.2 0.0 0.0 0.0 11.3 0.0 0.0 0.0 0.0 0.0 2.0 1.5 0.0 1.7 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.4 0.2 0.1 0.3 0.3 0.2 0.5 1.2 0.1 10.3 0.0 0.0 0.0 0.0 38.5 7.1 10.5 20.5 0.0 2.0 4.6 1.9 0.0 3.7 31.3 0.0 0.1 0.3 0.9 0.0 2.2 0.0 1.0 8.4 4.6 0.0 0.0 0.7 60.7 0.7 56.0 0.0 1.6 0.0 0.0 10.8 0.1 0.3 0.0 1.1 0.0 0.0 0.3 16.9 0.0 0.0 0.3 17.8 4.7 0.6 0.0 0.0 0.5 0.2 42.8 0.0 1.5 0.1 0.2 0.1 0.1 1.0 0.2 0.0 7.3 9.8 0.0 0.0 5.5 21.7 0.3 1.1 0.9 0.4 2.0 MYOM2 ENSG00000036448 "Myomesin 2" P54296 8 2045046-2165552 "Predicted intracellular proteins" "Muscle protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "heart muscle: 342.6;skeletal muscle: 387.9" "Group enriched" "Detected in many" 6 "Cardiomyocytes: 632.6;dendritic cells: 234.9;NK-cells: 268.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "HEK 293: 5.3;SCLC-21H: 2.2;U-266/84: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA001765, HPA005953" Enhanced Approved Mitochondria NA NA 290000 "Cluster 38: Heart - Muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA001765: AB_1079443, HPA005953: AB_1854258" "unprognostic (2.81e-2)" "unprognostic (1.11e-3)" "unprognostic (8.19e-2)" "unprognostic (1.35e-3)" "unprognostic (2.11e-1)" "unprognostic (1.86e-2)" "unprognostic (2.30e-5)" "unprognostic (1.10e-1)" "unprognostic (5.17e-2)" "unprognostic (1.34e-2)" "unprognostic (9.56e-2)" "unprognostic (2.54e-2)" "unprognostic (3.89e-2)" "unprognostic (2.71e-2)" "unprognostic (9.01e-2)" "unprognostic (3.22e-1)" "unprognostic (1.14e-1)" 0.1 0.2 0.3 0.1 1.1 0.2 6.1 1.8 1.6 0.2 0.0 0.6 0.2 0.3 0.7 1.2 0.3 0.1 342.6 1.0 0.0 2.7 0.4 0.7 0.1 0.0 0.0 0.1 0.2 0.0 0.2 0.3 0.0 3.7 0.1 0.4 1.9 0.6 387.9 0.8 0.4 0.4 0.0 2.2 0.3 0.4 0.1 0.0 0.1 62.4 0.0 0.4 0.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 5.3 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.1 1.8 1.6 1.0 0.0 0.0 0.0 0.0 0.0 0.1 1.3 3.7 6.4 3.0 11.8 1.6 3.6 2.7 2.0 1.2 3.2 2.7 5.1 632.6 20.0 1.0 3.7 0.0 0.0 234.9 1.8 13.7 4.6 15.2 2.7 1.8 5.6 0.0 3.6 21.8 1.7 0.1 26.7 0.5 1.9 5.7 1.5 4.6 6.8 1.4 6.7 2.8 2.1 2.0 2.7 5.1 8.3 0.6 4.8 3.6 3.7 3.0 7.3 268.8 1.5 2.0 2.5 0.8 1.5 11.1 1.2 1.2 26.0 5.3 4.8 0.0 11.6 13.9 55.9 21.4 1.3 2.8 0.1 22.3 1.5 1.2 1.4 MYORG "KIAA1161, NET37" ENSG00000164976 "Myogenesis regulating glycosidase (putative)" Q6NSJ0 9 34366666-34376898 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 84.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Cytotrophoblasts: 55.5;Exocrine glandular cells: 11.8;Pancreatic endocrine cells: 10.3;Proximal tubular cells: 9.2;Syncytiotrophoblasts: 17.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 35.4;SK-BR-3: 56.8;T-47d: 52.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060533, HPA067487" Enhanced Approved Mitochondria NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 80: Striated muscle - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA060533: AB_2684311, HPA067487: AB_2685848" "unprognostic (6.56e-2)" "unprognostic (1.51e-1)" "unprognostic (3.03e-2)" "prognostic unfavorable (6.96e-4)" "unprognostic (2.44e-1)" "unprognostic (1.20e-1)" "unprognostic (2.44e-1)" "unprognostic (2.03e-2)" "unprognostic (1.55e-1)" "unprognostic (4.68e-3)" "unprognostic (1.91e-3)" "unprognostic (3.20e-1)" "prognostic favorable (1.20e-13)" "unprognostic (4.08e-3)" "unprognostic (3.68e-1)" "unprognostic (3.09e-1)" "unprognostic (1.00e-3)" 8.1 6.2 30.6 3.4 30.3 2.0 3.4 27.1 31.5 1.7 16.8 19.0 27.3 2.7 1.9 5.3 4.5 6.1 3.9 28.4 28.2 14.5 41.5 3.2 1.5 34.0 33.5 1.0 11.1 1.5 5.5 19.8 28.7 3.2 16.2 3.4 5.6 5.2 84.2 3.7 25.8 4.4 24.5 1.4 15.0 1.3 31.8 1.1 1.9 39.2 1.8 3.1 2.4 24.2 8.1 5.5 9.2 5.6 3.8 1.2 19.7 1.4 1.1 0.8 1.3 13.9 8.3 4.4 15.9 1.4 4.0 16.4 6.7 15.5 1.1 1.4 3.6 0.8 24.6 35.4 0.5 0.8 2.7 1.8 7.2 2.6 3.0 4.3 3.8 3.3 1.1 4.2 2.0 13.4 2.5 1.2 5.5 27.4 4.4 4.0 4.6 1.3 4.9 2.9 1.3 13.0 10.8 56.8 0.9 7.8 52.8 1.3 3.2 1.8 11.0 1.6 3.5 2.8 6.5 1.6 1.6 3.1 1.6 0.4 0.1 0.2 0.7 0.1 0.5 0.2 0.4 0.4 0.0 0.2 0.2 0.3 0.3 0.4 0.1 0.1 0.6 0.1 30.6 30.3 27.1 31.5 28.4 28.2 34.0 33.5 28.7 24.5 31.8 24.2 3.9 9.6 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.0 2.7 0.0 0.0 2.5 3.7 0.0 55.5 0.3 0.0 1.9 5.7 0.0 3.4 0.7 2.1 0.0 0.0 0.0 11.8 3.6 1.1 0.0 2.0 1.3 0.2 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 0.0 9.2 2.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 17.4 0.3 0.1 0.0 0.0 NADK2 "C5orf33, FLJ30596, MNADK, NADKD1" ENSG00000152620 "NAD kinase 2, mitochondrial" Q4G0N4 5 36192589-36242279 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 11 "liver: 328.0" "Group enriched" "Detected in many" 5 "Astrocytes: 105.4;Early spermatids: 324.5;Hepatocytes: 211.9;Late spermatids: 154.9" "Cancer enhanced" "Detected in all" "liver cancer: 36.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038366, HPA038367, HPA061492" Enhanced Supported Mitochondria NA NA 30000 "Cluster 24: B-cells - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 23: Spermatids - Flagellum & Golgi organization" Mitochondria "HPA038366: AB_2675977, HPA038367: AB_10672743, HPA061492: AB_2684538" "unprognostic (1.15e-2)" "unprognostic (2.63e-2)" "unprognostic (3.01e-2)" "unprognostic (3.10e-3)" "unprognostic (1.64e-1)" "unprognostic (1.97e-2)" "unprognostic (4.06e-3)" "unprognostic (8.84e-2)" "unprognostic (3.32e-2)" "unprognostic (1.93e-3)" "unprognostic (1.09e-1)" "unprognostic (1.76e-1)" "unprognostic (9.73e-2)" "unprognostic (1.93e-1)" "unprognostic (1.58e-1)" "unprognostic (2.54e-2)" "unprognostic (1.75e-2)" 13.6 20.1 26.6 9.3 23.3 10.6 15.4 21.9 24.2 13.7 14.0 13.9 16.6 13.3 7.9 10.4 12.7 11.9 20.2 22.2 27.1 23.2 328.0 8.4 9.5 25.4 27.4 19.6 26.9 10.7 5.5 16.9 25.3 19.0 13.8 11.2 13.0 16.2 29.4 6.6 12.9 14.2 31.0 8.6 17.1 18.2 25.3 10.3 17.3 29.8 11.4 27.9 8.8 30.3 21.5 14.6 22.4 23.5 32.2 27.2 27.5 19.5 13.2 17.5 13.2 41.4 27.4 74.3 14.0 23.3 23.0 14.9 20.0 14.3 24.2 21.2 16.3 22.0 43.1 23.9 22.7 46.5 8.0 28.9 22.5 21.6 29.9 22.4 18.4 30.2 52.0 27.8 18.0 9.0 42.3 18.2 10.7 18.1 19.2 40.2 51.6 15.8 24.2 18.2 8.7 20.1 102.0 32.4 10.5 16.7 22.9 39.8 15.1 34.1 18.2 27.0 23.9 23.7 30.3 23.2 14.5 57.2 14.2 8.2 1.2 1.1 1.3 1.4 1.8 1.3 1.9 1.5 2.3 5.3 1.6 1.4 0.1 6.7 3.3 1.2 2.1 1.4 26.6 23.3 21.9 24.2 22.2 27.1 25.4 27.4 25.3 31.0 25.3 30.3 9.6 3.2 6.9 105.4 7.5 6.8 6.8 5.4 6.2 5.7 18.3 11.2 29.3 25.8 7.1 5.5 8.4 9.2 9.6 7.4 25.4 5.0 324.5 6.1 9.4 6.8 7.2 13.7 23.8 9.5 8.9 12.5 5.6 7.1 1.3 10.0 12.1 211.9 8.9 3.3 18.3 11.7 4.1 10.4 9.6 154.9 19.9 6.4 14.2 11.2 3.7 16.9 5.2 21.1 23.6 6.9 8.8 23.0 14.3 14.9 6.6 23.1 7.2 5.4 0.0 11.6 13.5 35.1 11.0 7.7 5.7 7.3 6.9 26.4 11.6 12.3 NAGS "AGAS, ARGA, NAT7" ENSG00000161653 "N-acetylglutamate synthase" Q8N159 17 44004622-44009068 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Urea cycle" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "intestine: 15.9;liver: 48.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 21.7;Proximal enterocytes: 44.2;Proximal tubular cells: 20.7;Spermatocytes: 16.0" "Cancer enhanced" "Detected in all" "liver cancer: 12.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 5.5;HHSteC: 5.2;TIME: 7.1;U-87 MG: 10.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA027300 Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "HPA027300: AB_2672207" "unprognostic (1.51e-3)" "unprognostic (9.24e-2)" "unprognostic (1.68e-1)" "unprognostic (8.67e-2)" "unprognostic (1.44e-2)" "unprognostic (1.30e-3)" "unprognostic (2.38e-2)" "unprognostic (1.98e-1)" "unprognostic (3.14e-2)" "unprognostic (2.73e-2)" "unprognostic (2.53e-3)" "unprognostic (1.46e-1)" "unprognostic (5.19e-2)" "unprognostic (6.99e-2)" "unprognostic (1.29e-2)" "unprognostic (1.22e-1)" "unprognostic (2.27e-1)" 0.9 0.7 2.0 0.5 1.2 0.0 1.4 0.9 2.0 0.8 0.0 2.4 15.9 0.8 1.8 1.4 0.7 0.4 1.2 1.0 3.5 4.9 48.2 1.9 0.3 2.0 1.4 0.6 0.3 3.3 0.5 0.1 2.2 1.1 0.5 0.0 1.0 1.4 0.2 1.0 13.6 0.1 1.3 0.4 0.4 0.6 3.6 0.1 4.4 0.2 0.1 0.4 1.0 1.0 2.9 0.1 0.0 0.4 0.0 5.5 0.1 0.5 0.1 0.1 0.2 1.7 0.7 0.0 1.1 0.0 0.1 1.3 0.1 1.5 0.3 0.2 0.7 0.1 0.2 2.2 5.2 0.0 0.0 3.2 0.0 0.7 0.0 0.6 1.4 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.4 1.5 2.7 0.0 0.3 0.0 0.1 0.0 2.1 0.0 0.9 0.0 0.0 0.2 0.2 0.0 7.1 2.5 0.7 0.2 0.6 0.1 0.1 0.1 10.0 0.0 0.3 0.8 0.5 0.7 0.9 0.4 0.7 0.3 0.6 0.8 0.5 0.3 0.3 0.4 0.3 0.2 0.8 0.1 0.5 0.3 2.0 1.2 0.9 2.0 1.0 3.5 2.0 1.4 2.2 1.3 3.6 1.0 1.8 3.2 4.2 0.0 0.9 1.5 0.9 1.9 6.8 0.4 3.5 4.8 2.6 2.8 2.9 12.9 0.0 0.9 1.1 10.5 7.9 1.9 5.8 0.5 0.2 2.3 7.2 0.0 0.0 4.2 1.9 0.9 2.0 0.2 0.0 0.3 0.7 21.7 1.1 0.0 0.3 3.8 4.1 1.9 5.3 5.3 1.5 2.1 0.0 1.0 6.1 1.0 3.1 0.0 0.0 5.1 11.1 0.7 0.0 0.6 44.2 20.7 1.1 0.5 0.0 0.2 0.9 16.0 2.5 1.0 0.9 0.4 1.4 0.7 6.6 0.6 NAT14 KLP1 ENSG00000090971 "N-acetyltransferase 14 (putative)" Q8WUY8 19 55485188-55487568 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Activator, Acyltransferase, DNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 62.6;Horizontal cells: 148.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "HEK 293: 168.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047187 Approved Mitochondria NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 62: Horizontal cells - Visual perception" Mitochondria "HPA047187: AB_2679974" "unprognostic (5.96e-2)" "unprognostic (1.10e-1)" "unprognostic (2.92e-2)" "unprognostic (5.43e-2)" "unprognostic (1.32e-1)" "unprognostic (3.59e-2)" "unprognostic (1.69e-2)" "unprognostic (7.01e-2)" "unprognostic (1.94e-1)" "unprognostic (2.97e-1)" "unprognostic (9.12e-2)" "unprognostic (6.41e-2)" "prognostic unfavorable (3.61e-4)" "unprognostic (7.00e-2)" "unprognostic (6.74e-2)" "unprognostic (9.85e-2)" "unprognostic (1.58e-1)" 5.3 13.1 32.9 4.5 32.2 3.9 7.5 32.2 37.8 23.5 30.2 20.5 2.4 23.8 7.8 5.2 25.2 4.0 11.6 33.8 32.5 25.5 6.5 10.5 3.8 29.8 32.9 20.6 8.4 10.7 47.1 6.9 28.7 14.9 2.1 8.4 5.3 7.8 3.0 5.7 8.5 8.8 27.8 7.1 10.1 11.6 36.2 53.6 20.0 1.2 2.9 11.8 10.8 29.0 8.2 27.6 32.1 59.8 12.9 16.3 19.4 29.6 35.5 32.5 46.3 9.7 26.6 3.1 10.3 19.5 16.4 10.6 20.8 18.8 20.0 32.9 168.2 26.1 41.0 21.9 23.3 19.4 25.8 22.7 6.5 22.7 6.2 65.5 24.3 46.9 32.3 9.1 19.7 10.0 33.1 29.7 44.2 16.4 13.1 32.7 19.9 12.6 78.2 15.3 93.4 64.5 11.9 17.8 28.9 12.2 14.5 20.0 28.5 11.8 31.5 1.7 24.5 18.0 7.4 13.7 26.7 3.3 30.5 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.4 0.1 0.0 0.4 0.0 0.1 32.9 32.2 32.2 37.8 33.8 32.5 29.8 32.9 28.7 27.8 36.2 29.0 4.0 6.4 3.2 9.1 3.8 2.9 6.7 4.4 4.6 62.6 11.7 13.8 4.1 5.7 2.6 29.5 35.5 13.3 3.8 1.2 15.6 14.5 1.5 41.7 31.7 7.2 12.7 10.3 12.9 1.1 8.3 10.4 3.1 9.7 0.0 11.5 3.9 3.6 2.9 148.0 13.1 2.1 4.1 0.8 2.4 3.1 11.8 1.7 5.4 2.8 2.3 39.6 1.0 7.1 2.8 4.3 0.4 10.5 2.7 4.4 0.7 3.7 18.1 39.9 0.0 13.8 12.1 4.2 3.9 0.7 0.6 6.0 2.6 9.7 1.1 1.9 NAT8L "FLJ37478, Hcml3, Shati" ENSG00000185818 "N-acetyltransferase 8 like" Q8N9F0 4 2059327-2069089 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "adipose tissue: 43.5;brain: 99.0" "Cell type enhanced" "Detected in some" "Astrocytes: 126.7;Excitatory neurons: 46.0;Horizontal cells: 80.8;Inhibitory neurons: 37.6;Muller glia cells: 25.0" "Group enriched" "Detected in many" 6 "endometrial cancer: 6.2;glioma: 17.2;melanoma: 14.6;ovarian cancer: 8.0;thyroid cancer: 7.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NB-4: 20.8;SCLC-21H: 25.8;SK-MEL-30: 21.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040677 Approved Mitochondria NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 64: Astrocytes - Nervous system maintenance" Mitochondria "HPA040677: AB_2732486" "unprognostic (1.32e-2)" "unprognostic (8.62e-2)" "unprognostic (3.02e-3)" "prognostic unfavorable (1.01e-5)" "unprognostic (2.56e-1)" "unprognostic (2.63e-4)" "unprognostic (6.58e-2)" "unprognostic (1.79e-1)" "unprognostic (2.90e-2)" "unprognostic (4.54e-1)" "unprognostic (3.70e-2)" "unprognostic (7.06e-2)" "unprognostic (1.78e-3)" "unprognostic (7.24e-3)" "unprognostic (1.14e-2)" "unprognostic (2.10e-2)" "unprognostic (1.35e-2)" 43.5 0.7 56.1 0.1 46.4 0.0 1.6 42.9 99.0 0.0 0.6 0.2 0.1 0.3 1.3 0.1 0.9 0.1 0.8 45.8 29.0 5.3 0.0 0.0 0.2 52.3 46.4 0.2 2.3 0.9 1.8 0.1 57.5 1.0 0.1 3.7 2.3 1.6 5.7 1.0 0.2 0.2 33.0 0.3 0.4 9.0 88.8 0.2 0.3 2.5 0.0 0.0 0.0 38.9 0.1 9.2 4.9 10.0 0.9 0.0 5.7 0.2 0.0 0.2 0.0 4.1 0.3 0.0 1.9 0.0 1.5 0.1 11.1 0.0 0.1 0.0 13.2 0.1 2.1 6.6 1.5 14.5 6.9 0.0 0.2 0.0 0.0 1.8 0.0 3.4 11.5 0.0 0.4 6.2 0.2 20.8 14.1 0.0 4.1 0.7 2.3 0.4 0.2 0.5 25.8 8.6 6.6 0.0 21.4 0.8 0.7 8.3 0.0 0.0 3.3 0.1 5.6 0.0 0.0 0.2 0.0 6.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 56.1 46.4 42.9 99.0 45.8 29.0 52.3 46.4 57.5 33.0 88.8 38.9 0.5 0.0 0.0 126.7 0.0 0.3 0.0 0.0 0.0 14.5 1.4 2.2 2.6 0.0 0.0 1.8 6.2 0.0 5.4 0.0 0.0 4.6 1.1 1.7 0.1 0.4 1.8 0.0 46.0 0.6 0.1 0.2 0.0 1.0 0.0 21.9 0.0 0.0 0.8 80.8 37.6 0.0 0.0 0.0 0.3 3.8 0.0 0.7 10.6 17.8 0.0 25.0 0.0 23.1 15.7 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.6 0.0 0.0 0.8 0.5 1.5 0.0 0.1 0.0 0.0 0.1 0.0 0.1 NDUFA10 CI-42k ENSG00000130414 "NADH:ubiquinone oxidoreductase subunit A10" O95299 2 239892450-240025743 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 332.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059529, HPA067045, CAB070846" Approved Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB070846: AB_11152346, HPA059529: AB_2684051, HPA067045: AB_2732756" "unprognostic (2.12e-2)" "unprognostic (8.94e-3)" "unprognostic (8.73e-2)" "unprognostic (2.02e-2)" "unprognostic (8.96e-2)" "unprognostic (2.53e-1)" "unprognostic (8.78e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.95e-4)" "unprognostic (5.71e-2)" "unprognostic (2.47e-2)" "unprognostic (1.05e-1)" "prognostic favorable (2.09e-7)" "unprognostic (1.16e-1)" "unprognostic (4.96e-2)" "unprognostic (1.98e-1)" "unprognostic (2.95e-1)" 55.4 91.1 36.3 29.6 40.2 50.3 50.3 39.8 51.2 41.0 38.9 83.2 81.6 37.8 28.3 74.6 43.6 31.2 184.8 41.7 36.0 94.2 103.6 35.4 32.3 41.9 39.4 45.4 58.5 99.3 38.5 37.9 41.3 33.1 84.3 31.2 55.9 33.1 206.4 72.4 64.3 39.8 34.0 37.7 71.7 35.3 37.7 45.3 38.8 332.0 49.7 47.3 49.2 39.4 74.4 65.5 46.3 81.5 54.8 95.4 75.5 49.0 70.9 71.3 77.8 72.8 82.8 51.0 31.8 64.2 60.8 96.2 109.8 103.1 92.6 59.7 90.9 72.9 65.6 174.6 72.4 96.9 58.6 95.5 80.3 68.5 85.0 66.6 96.6 74.6 102.0 34.8 81.8 124.8 95.6 110.5 56.3 114.4 81.0 93.2 114.4 81.2 108.7 152.1 70.5 54.6 55.3 131.8 108.9 33.3 121.2 97.4 69.9 52.7 60.7 70.7 75.8 77.3 24.6 79.2 60.3 80.9 72.8 30.2 106.3 47.1 72.9 115.8 93.8 95.4 70.7 77.5 147.9 77.0 68.2 69.4 26.7 97.6 103.3 49.7 92.7 104.6 36.3 40.2 39.8 51.2 41.7 36.0 41.9 39.4 41.3 34.0 37.7 39.4 66.8 76.9 74.1 31.6 63.5 104.9 96.5 193.5 60.3 80.8 88.4 89.5 354.8 87.2 114.0 77.3 62.6 216.4 58.1 137.3 311.0 112.5 47.5 66.8 83.2 67.4 92.9 57.6 83.1 78.5 124.0 71.7 62.2 76.6 65.9 103.7 66.4 139.1 125.2 50.5 68.5 152.3 103.7 90.5 82.0 85.3 50.1 65.2 112.1 27.2 107.8 72.2 53.5 37.7 71.4 77.7 125.5 49.2 56.7 62.1 182.7 303.0 77.7 110.4 65.7 74.6 77.3 84.2 73.4 107.2 118.9 218.1 63.0 185.3 234.2 110.0 NDUFA11 B14.7 ENSG00000174886 "NADH:ubiquinone oxidoreductase subunit A11" Q86Y39 19 5891276-5904006 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 1107.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA072209 Uncertain Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA072209: AB_2686495" "unprognostic (2.24e-1)" "prognostic favorable (4.54e-5)" "unprognostic (8.20e-3)" "prognostic favorable (3.38e-5)" "unprognostic (4.54e-2)" "unprognostic (7.73e-2)" "unprognostic (6.30e-2)" "unprognostic (7.26e-3)" "unprognostic (3.95e-1)" "unprognostic (4.20e-2)" "unprognostic (1.67e-3)" "unprognostic (9.02e-2)" "unprognostic (1.12e-2)" "unprognostic (2.91e-1)" "unprognostic (1.16e-1)" "unprognostic (3.40e-2)" "unprognostic (6.16e-3)" 199.0 429.8 203.3 93.4 207.7 158.1 188.9 226.1 305.6 202.1 205.3 312.2 124.9 219.6 53.1 283.4 201.5 106.6 687.5 206.8 223.5 290.2 380.5 155.1 145.3 212.7 213.8 200.7 205.7 138.7 205.9 96.9 215.7 228.3 56.1 31.7 231.2 105.4 425.5 187.6 185.6 89.4 218.3 196.4 250.4 96.3 218.8 120.7 188.9 330.6 62.7 209.4 215.5 225.2 315.2 227.6 168.7 273.1 138.9 231.5 191.2 209.8 243.9 369.4 341.5 271.9 155.5 300.4 320.0 209.6 163.9 195.4 118.6 250.8 85.7 271.2 466.9 124.4 194.5 434.4 374.3 188.8 174.4 317.3 221.9 219.9 106.6 147.6 250.7 284.5 257.3 316.4 192.4 228.2 484.1 325.0 249.9 249.1 609.2 325.0 214.2 427.9 238.3 194.9 236.2 254.3 163.5 254.3 381.5 72.9 196.1 395.0 224.9 202.8 194.7 410.1 340.1 493.5 460.1 400.6 341.0 443.1 263.7 421.2 526.8 313.4 313.2 440.5 323.9 394.4 341.2 314.6 461.1 343.7 321.0 281.1 239.0 303.9 387.8 550.1 474.0 870.2 203.3 207.7 226.1 305.6 206.8 223.5 212.7 213.8 215.7 218.3 218.8 225.2 189.9 144.2 198.0 22.5 179.2 205.6 236.8 306.8 99.6 60.1 279.3 430.3 436.9 267.4 202.9 292.4 25.0 585.4 164.2 429.9 841.2 286.0 157.4 199.8 146.9 175.6 351.5 208.9 12.9 301.6 595.6 224.3 114.7 137.6 213.0 135.5 272.7 735.4 423.7 50.5 16.6 477.0 207.5 347.7 234.1 452.4 194.8 197.7 286.4 14.0 403.3 198.0 220.4 5.5 31.2 287.1 446.6 167.3 208.5 283.5 606.9 1107.9 176.7 89.6 118.3 174.3 210.0 97.2 91.8 162.5 243.5 593.4 156.9 159.0 451.1 241.3 NDUFA13 "B16.6, CDA016, CGI-39, GRIM-19, GRIM19" ENSG00000186010 "NADH:ubiquinone oxidoreductase subunit A13" Q9P0J0 19 19515736-19529054 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Apoptosis, Electron transport, Host-virus interaction, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 2947.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041213 Supported Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "HPA041213: AB_10794988" "unprognostic (2.87e-1)" "unprognostic (2.88e-3)" "unprognostic (9.98e-2)" "unprognostic (1.11e-1)" "unprognostic (3.36e-2)" "unprognostic (5.78e-2)" "unprognostic (6.00e-2)" "unprognostic (3.30e-2)" "unprognostic (2.81e-1)" "unprognostic (1.83e-3)" "unprognostic (1.26e-2)" "unprognostic (1.13e-1)" "unprognostic (1.45e-2)" "unprognostic (1.33e-1)" "unprognostic (2.37e-1)" "unprognostic (2.15e-2)" "unprognostic (2.15e-2)" 268.1 248.1 586.0 184.1 601.2 318.9 226.6 612.2 726.3 188.2 632.2 324.0 268.5 129.8 414.0 288.3 253.0 165.0 987.1 577.4 609.2 274.5 301.3 154.8 234.9 600.9 585.1 168.3 274.3 541.3 154.7 186.6 588.3 216.1 212.4 100.7 272.8 220.4 1093.2 183.1 245.1 193.5 593.6 160.6 251.2 208.5 624.2 254.5 221.2 1102.9 178.5 250.9 103.5 607.7 371.4 405.5 443.7 531.6 460.2 416.2 606.4 345.8 488.3 500.0 492.2 639.4 584.9 442.6 952.2 495.2 261.4 307.2 313.0 477.6 177.3 276.5 1052.6 308.9 590.9 834.1 448.0 601.1 517.0 546.5 483.7 322.7 335.5 296.3 382.8 533.1 428.6 728.2 400.3 1115.4 811.2 880.9 528.4 846.6 1004.4 536.0 263.0 830.2 711.1 782.6 508.9 633.2 350.0 551.7 481.1 225.2 367.7 1035.9 307.3 538.4 177.5 583.8 541.0 543.6 430.6 510.3 428.4 624.2 390.8 1210.3 1162.6 963.4 758.6 1263.4 678.0 1284.6 874.1 838.9 1165.9 1097.3 831.6 775.7 411.9 779.9 1054.3 979.4 1246.2 2090.8 586.0 601.2 612.2 726.3 577.4 609.2 600.9 585.1 588.3 593.6 624.2 607.7 155.1 131.4 184.8 33.0 194.5 129.0 75.9 346.9 117.8 64.8 211.3 181.2 514.5 224.4 251.2 250.1 25.0 426.6 136.6 951.6 610.5 566.0 411.8 154.5 111.5 131.4 556.3 185.3 22.7 578.5 357.2 173.1 225.3 130.5 259.3 51.3 182.4 422.6 333.6 42.1 27.2 719.7 268.5 307.4 197.9 2947.1 153.4 198.3 263.3 19.7 456.7 186.3 183.4 17.6 41.2 490.5 931.9 129.1 272.0 75.0 1114.7 772.0 236.5 84.2 92.1 91.6 196.2 80.6 111.5 210.0 127.0 498.4 177.5 48.0 683.0 87.4 NDUFA4 "CI-9k, COXFA4, MLRQ" ENSG00000189043 "NDUFA4 mitochondrial complex associated" O00483 7 10931943-10940153 "Disease related genes, Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 513.5;skeletal muscle: 525.0;tongue: 652.5" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 4615.5;Distal tubular cells: 3960.0;Proximal tubular cells: 3331.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055323, HPA078265" Approved Supported Mitochondria NA NA 50000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA055323: , HPA078265: " "unprognostic (1.83e-1)" "unprognostic (6.64e-2)" "unprognostic (1.65e-1)" "unprognostic (1.51e-1)" "unprognostic (2.16e-1)" "unprognostic (4.97e-3)" "unprognostic (3.85e-1)" "unprognostic (2.25e-1)" "unprognostic (1.69e-1)" "unprognostic (3.90e-2)" "unprognostic (8.65e-3)" "unprognostic (1.74e-1)" "prognostic favorable (4.61e-8)" "unprognostic (1.24e-1)" "unprognostic (1.94e-1)" "unprognostic (1.44e-3)" "unprognostic (2.08e-1)" 78.6 90.1 188.7 40.8 196.2 67.5 76.0 192.9 263.4 54.7 192.8 84.1 74.2 74.2 81.1 66.9 69.5 36.2 513.5 201.9 205.0 156.6 140.3 62.8 42.5 194.4 189.6 60.1 61.3 251.9 23.3 31.6 197.6 66.0 56.6 128.4 108.6 84.4 525.0 58.3 58.8 60.9 194.1 59.6 107.0 24.3 194.3 64.0 66.3 652.5 46.1 73.7 54.1 200.1 55.3 90.9 155.0 176.8 84.0 78.4 70.3 68.2 63.2 61.3 53.6 115.2 144.7 104.6 63.0 96.7 168.0 94.1 102.1 79.4 66.5 52.2 74.0 88.2 93.4 108.6 73.2 123.3 84.3 84.8 78.4 75.4 66.0 116.7 86.6 92.7 133.2 139.0 129.8 103.8 56.2 109.3 169.2 364.2 181.6 74.7 108.6 118.6 158.0 115.4 95.2 99.7 106.9 303.7 64.7 210.3 191.6 149.6 76.8 73.3 102.0 107.0 115.0 84.6 115.8 120.5 101.3 130.8 232.5 236.7 110.2 160.6 74.3 135.8 88.3 95.7 103.3 93.9 138.9 74.6 106.1 93.3 25.3 79.4 146.4 131.2 131.6 192.8 188.7 196.2 192.9 263.4 201.9 205.0 194.4 189.6 197.6 194.1 194.3 200.1 422.2 490.4 470.7 52.9 366.9 407.1 605.8 1642.7 307.9 521.0 742.3 936.0 4615.5 843.6 879.3 952.7 266.9 875.9 357.5 543.8 3960.0 865.1 160.6 626.2 471.6 447.0 209.7 358.3 54.1 955.5 763.9 557.9 404.7 477.7 576.4 507.5 656.1 1887.5 964.5 158.2 72.7 780.8 1373.2 589.0 589.8 106.8 493.6 517.6 916.0 49.6 596.6 721.5 374.9 36.7 57.9 776.6 626.7 784.3 467.9 696.6 596.2 3331.1 803.0 666.0 335.2 546.5 846.5 172.7 295.5 581.7 482.9 658.8 389.1 443.5 712.4 803.2 NDUFA4L2 "COXFA4L2, FLJ26118, NUOMS" ENSG00000185633 "NDUFA4 mitochondrial complex associated like 2" Q9NRX3 12 57234903-57240715 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 304.9" "Group enriched" "Detected in many" 4 "Muller glia cells: 627.0;Sertoli cells: 1130.7;Smooth muscle cells: 525.6" "Cancer enriched" "Detected in all" 5 "renal cancer: 356.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 7 "AN3-CA: 133.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055323, HPA078265" Uncertain Approved Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria "HPA055323: , HPA078265: " "unprognostic (1.25e-1)" "unprognostic (1.60e-1)" "unprognostic (2.11e-3)" "unprognostic (3.23e-3)" "unprognostic (5.06e-2)" "unprognostic (1.22e-2)" "unprognostic (2.25e-2)" "unprognostic (3.53e-1)" "unprognostic (6.67e-2)" "unprognostic (5.79e-2)" "unprognostic (2.13e-1)" "unprognostic (2.89e-1)" "prognostic unfavorable (1.37e-5)" "unprognostic (9.10e-3)" "unprognostic (1.31e-1)" "unprognostic (6.41e-2)" "unprognostic (2.74e-2)" 85.6 14.0 41.6 6.8 40.1 0.2 55.1 41.4 61.5 109.3 36.8 17.4 5.8 20.7 2.4 304.9 15.5 17.1 180.1 40.3 41.1 47.6 20.9 62.6 5.8 43.0 42.7 14.0 14.5 12.1 30.9 71.7 48.8 27.3 1.9 29.4 55.8 9.8 43.8 206.9 14.2 7.5 38.9 74.1 18.0 8.7 43.5 3.2 54.5 29.2 4.8 27.7 183.5 45.4 0.9 1.3 0.3 133.9 5.4 3.1 0.4 2.1 1.5 0.6 1.3 0.0 1.5 5.5 5.6 2.1 0.1 1.2 0.7 1.0 0.0 3.0 0.2 0.6 0.3 0.1 18.6 4.1 2.0 12.0 2.5 0.2 4.7 0.9 0.0 7.6 0.5 7.2 0.4 2.7 1.1 0.2 0.3 0.6 2.4 2.1 1.0 11.0 0.1 0.1 7.1 2.5 0.2 0.3 4.7 0.1 1.5 14.5 0.6 1.2 0.1 1.1 0.7 10.0 3.5 2.5 4.9 9.8 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 41.6 40.1 41.4 61.5 40.3 41.1 43.0 42.7 48.8 38.9 43.5 45.4 156.0 0.0 0.5 2.6 2.6 151.2 0.9 89.2 6.8 30.6 2.6 5.8 1.2 0.0 24.8 0.0 18.8 1.0 0.9 0.1 0.0 1.6 1.7 0.4 3.0 91.8 0.0 0.0 2.2 0.0 1.5 21.5 4.6 0.3 8.9 0.1 2.9 1.3 1.9 11.8 3.0 0.2 54.9 0.0 28.9 3.0 3.1 2.0 30.2 18.7 1.0 627.0 0.0 0.5 0.4 4.7 0.0 2.2 1.4 2.0 0.1 0.3 6.2 25.7 1130.7 13.0 525.6 12.3 5.5 20.3 161.4 1.1 1.9 2.5 0.2 1.4 NDUFA7 B14.5a ENSG00000267855 "NADH:ubiquinone oxidoreductase subunit A7" O95182 19 8308768-8321375 "Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 245.6" "Cell type enhanced" "Detected in many" "Pancreatic endocrine cells: 167.5;Proximal enterocytes: 183.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA059251, HPA071866" Enhanced Supported Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA059251: AB_2683960, HPA071866: AB_2686465" "unprognostic (6.55e-2)" "unprognostic (1.02e-3)" "unprognostic (1.11e-1)" "unprognostic (3.85e-1)" "unprognostic (2.18e-1)" "unprognostic (5.65e-2)" "unprognostic (1.37e-1)" "unprognostic (1.43e-2)" "unprognostic (3.40e-1)" "unprognostic (1.13e-3)" "unprognostic (1.81e-2)" "unprognostic (1.43e-1)" "unprognostic (1.09e-2)" "unprognostic (5.53e-2)" "unprognostic (1.29e-2)" "unprognostic (2.59e-2)" "unprognostic (9.35e-3)" 39.4 87.5 86.2 19.8 90.0 34.2 33.1 89.8 96.1 21.3 95.9 46.6 24.2 27.7 53.5 57.6 42.3 25.1 168.1 87.6 90.0 88.3 83.4 31.0 29.6 87.1 88.1 25.1 37.1 103.7 86.4 23.4 87.3 41.2 33.5 32.3 43.5 20.7 245.6 30.7 34.0 22.8 87.3 42.0 54.7 18.7 89.1 40.8 41.3 244.7 32.2 35.5 28.2 87.7 78.9 62.8 64.7 43.3 42.6 32.3 44.2 16.5 18.0 56.0 44.1 57.7 59.7 36.1 25.1 42.6 35.0 65.1 29.0 97.4 33.8 88.3 173.6 26.6 90.1 157.7 63.9 45.8 45.1 43.3 61.7 25.2 39.1 57.1 72.3 141.2 57.0 217.7 80.6 89.4 93.5 236.1 65.1 119.9 187.7 52.2 13.7 99.0 117.6 40.8 65.9 50.5 19.0 90.6 58.5 40.1 33.0 74.8 26.4 42.5 34.0 61.6 60.1 79.2 58.0 49.9 67.8 80.2 77.3 61.9 104.5 80.2 62.1 124.6 65.4 83.3 66.7 58.2 130.5 81.6 66.0 61.6 30.5 81.8 117.6 186.1 95.3 82.6 86.2 90.0 89.8 96.1 87.6 90.0 87.1 88.1 87.3 87.3 89.1 87.7 19.5 44.8 68.4 10.1 28.4 0.0 10.3 0.0 21.1 14.9 51.6 38.1 0.0 44.3 20.4 53.3 6.2 62.0 32.6 57.6 99.7 147.3 38.9 36.1 10.5 19.8 87.4 44.2 9.5 157.2 45.4 15.0 28.1 19.4 21.5 8.4 27.5 64.0 52.8 8.4 13.3 101.6 0.0 42.7 0.0 17.7 13.4 30.4 0.0 10.3 122.5 27.9 45.3 9.5 13.2 167.5 110.2 13.2 61.6 14.7 183.8 97.6 70.7 17.1 6.6 7.3 19.6 24.8 27.5 53.3 0.0 46.9 20.9 11.7 107.6 12.1 NDUFA8 "MGC793, PGIV" ENSG00000119421 "NADH:ubiquinone oxidoreductase subunit A8" P51970 9 122144058-122159779 "Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 380.1;tongue: 363.3" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 579.5;Distal tubular cells: 614.3;Early spermatids: 499.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041510, HPA041600" Enhanced Supported Mitochondria NA NA 25000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA041510: AB_10794379, HPA041600: AB_10796778" "unprognostic (2.90e-1)" "unprognostic (2.27e-3)" "unprognostic (3.58e-1)" "unprognostic (3.42e-2)" "unprognostic (2.32e-1)" "unprognostic (2.20e-2)" "unprognostic (1.07e-2)" "unprognostic (1.98e-2)" "unprognostic (2.33e-2)" "unprognostic (6.98e-2)" "unprognostic (1.46e-2)" "unprognostic (4.12e-2)" "prognostic favorable (4.17e-6)" "unprognostic (1.80e-1)" "unprognostic (1.96e-1)" "unprognostic (1.04e-1)" "unprognostic (4.62e-2)" 54.2 74.2 139.4 33.9 146.0 28.6 53.9 146.0 159.3 44.8 142.6 101.4 65.8 46.6 86.8 57.1 62.3 39.3 380.1 144.7 148.4 97.9 81.5 37.0 43.0 141.4 139.7 35.7 46.1 137.4 56.9 48.2 141.6 57.9 88.2 72.0 72.3 61.9 259.1 44.2 53.6 73.9 138.7 41.4 75.3 95.5 145.8 48.6 53.3 363.3 56.2 57.8 40.9 141.7 84.8 154.1 99.5 132.0 105.7 96.4 123.3 96.0 114.1 130.0 108.5 197.0 81.9 123.1 92.6 113.6 234.6 206.8 191.3 208.7 127.0 121.5 132.6 96.9 254.2 172.6 113.3 172.7 95.5 106.1 200.3 130.0 82.9 118.1 189.1 134.8 151.0 89.6 150.3 215.6 108.1 112.1 91.2 377.1 293.1 85.0 156.7 179.4 189.4 116.0 172.1 67.6 151.0 176.7 122.6 100.9 187.6 82.1 123.2 71.2 70.9 135.2 109.3 100.1 176.1 123.8 148.0 110.7 120.2 17.4 82.1 66.8 78.3 100.9 76.2 88.0 71.3 77.3 109.2 92.8 76.0 80.3 13.7 79.0 88.7 114.2 91.9 74.7 139.4 146.0 146.0 159.3 144.7 148.4 141.4 139.7 141.6 138.7 145.8 141.7 70.6 28.9 40.4 16.3 38.6 48.3 73.8 298.1 43.9 47.2 61.0 73.5 579.5 48.6 128.0 82.8 29.2 130.5 34.1 87.3 614.3 103.8 499.0 80.1 52.4 98.5 77.4 100.6 19.4 101.6 113.1 70.3 47.9 52.9 20.3 68.5 60.7 110.9 124.4 45.4 26.0 105.7 185.1 40.5 42.0 121.1 56.5 48.8 94.3 18.7 72.9 91.3 65.9 14.1 17.9 100.8 80.3 75.2 56.9 91.1 163.4 249.8 113.0 59.0 26.3 52.5 114.8 294.9 116.2 67.0 56.8 126.6 36.6 104.4 136.3 86.4 NDUFAF2 "B17.2L, mimitin, MMTN, NDUFA12L" ENSG00000164182 "NADH:ubiquinone oxidoreductase complex assembly factor 2" Q8N183 5 60945177-61154531 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA048082, HPA054776" Supported Enhanced Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 47: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA048082: AB_2680254, HPA054776: AB_2682598" "unprognostic (7.28e-2)" "unprognostic (6.83e-2)" "unprognostic (1.37e-1)" "unprognostic (2.46e-3)" "unprognostic (2.41e-2)" "unprognostic (2.74e-2)" "prognostic unfavorable (2.56e-4)" "unprognostic (1.06e-1)" "unprognostic (4.76e-2)" "unprognostic (8.40e-3)" "unprognostic (1.28e-1)" "unprognostic (2.71e-1)" "prognostic unfavorable (2.49e-4)" "unprognostic (1.79e-2)" "unprognostic (6.10e-2)" "unprognostic (2.37e-1)" "unprognostic (4.66e-2)" 42.7 39.2 34.8 23.3 35.7 18.0 38.5 34.6 56.0 34.7 33.0 48.3 21.0 31.6 17.5 36.4 31.3 17.0 57.7 34.8 37.5 37.4 32.2 24.9 19.7 36.2 37.9 37.7 35.7 31.2 45.1 14.5 37.3 31.9 26.2 22.0 25.8 23.0 80.2 22.6 24.9 25.9 34.4 18.3 35.9 31.2 35.4 13.0 23.0 46.5 18.8 43.4 33.4 35.0 109.0 51.9 41.6 129.1 80.7 113.8 70.3 129.8 71.1 85.2 103.7 99.4 84.0 150.8 127.5 91.2 141.2 44.2 72.6 113.8 103.6 66.0 104.3 52.1 95.7 99.4 115.6 72.5 26.2 59.7 119.2 74.9 226.0 53.9 74.7 64.0 79.5 76.3 90.9 89.6 64.2 108.0 35.3 41.2 135.0 77.3 115.1 192.7 83.1 46.1 84.8 33.0 74.7 72.7 136.0 35.8 86.1 40.4 68.6 55.5 82.8 125.3 134.2 46.0 73.2 170.8 75.9 123.2 66.3 0.4 18.3 2.4 17.3 19.1 21.1 23.0 22.3 21.1 32.1 15.2 18.6 20.1 0.8 27.1 15.8 11.0 31.7 12.2 34.8 35.7 34.6 56.0 34.8 37.5 36.2 37.9 37.3 34.4 35.4 35.0 40.8 12.8 28.0 23.8 32.8 60.5 64.6 62.2 34.1 27.9 47.9 59.8 87.6 45.8 39.6 38.6 12.5 20.8 18.7 29.8 93.9 55.1 175.7 41.8 95.1 35.8 24.7 28.8 62.2 56.6 49.2 60.4 28.5 40.3 20.3 27.2 31.8 94.6 51.4 42.1 68.8 59.3 40.7 29.5 59.1 22.2 76.7 29.0 44.4 40.3 24.7 34.0 22.6 61.9 71.3 69.8 52.2 62.1 29.0 144.1 32.2 151.4 25.9 29.1 26.3 55.2 60.1 108.4 73.9 63.0 63.6 14.2 34.0 48.5 65.7 71.1 NDUFAF4 "bA22L21.1, C6orf66, HRPAP20, HSPC125, My013" ENSG00000123545 "NADH:ubiquinone oxidoreductase complex assembly factor 4" Q9P032 6 96889315-96897891 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction" Calmodulin-binding "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 168.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046560 Uncertain Supported Mitochondria NA Yes "Cluster 30: Non-specific - Translation" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA046560: AB_10966700" "prognostic unfavorable (1.31e-4)" "unprognostic (1.32e-1)" "unprognostic (1.09e-2)" "unprognostic (1.14e-3)" "unprognostic (2.89e-1)" "unprognostic (7.53e-3)" "unprognostic (6.89e-2)" "unprognostic (1.27e-1)" "unprognostic (5.57e-2)" "unprognostic (2.78e-2)" "unprognostic (2.03e-2)" "unprognostic (1.13e-1)" "unprognostic (4.20e-3)" "unprognostic (6.32e-2)" "unprognostic (1.11e-1)" "unprognostic (4.87e-2)" "unprognostic (1.31e-1)" 5.7 7.9 13.3 3.4 14.7 2.2 7.0 16.8 21.4 6.4 10.4 7.4 4.9 5.5 4.7 5.4 4.4 4.5 25.6 14.7 15.6 12.6 9.3 3.2 4.7 14.9 14.5 7.8 5.5 10.1 2.5 4.8 15.6 7.2 7.5 9.8 6.2 9.6 23.2 4.8 4.4 5.6 12.3 4.9 4.7 4.6 16.6 5.3 7.4 31.1 4.7 7.8 3.7 13.7 2.2 6.1 10.5 14.3 10.3 5.9 5.6 6.0 5.6 8.8 6.6 8.4 3.7 20.6 10.7 5.6 8.4 4.4 24.7 9.3 8.5 14.5 19.5 23.0 3.2 7.4 11.2 24.4 9.2 5.7 14.2 7.6 7.7 4.4 6.9 14.3 21.0 13.6 13.9 7.0 15.7 13.1 20.1 11.3 10.0 7.4 5.9 10.7 14.6 6.0 17.9 8.4 3.1 10.7 17.5 10.2 3.3 16.1 5.8 4.6 3.5 16.2 9.9 3.1 5.4 20.0 6.2 18.1 6.9 0.2 1.8 0.5 4.0 3.6 5.3 5.1 5.2 5.4 3.3 5.4 7.6 6.9 0.3 3.0 2.3 3.8 5.9 3.2 13.3 14.7 16.8 21.4 14.7 15.6 14.9 14.5 15.6 12.3 16.6 13.7 31.9 9.6 19.8 9.8 43.2 108.8 74.4 82.6 60.9 15.1 28.5 48.1 126.9 25.8 37.3 23.9 0.0 49.6 27.9 23.5 168.3 37.7 3.3 19.2 18.3 30.7 39.3 23.3 18.5 27.6 47.6 34.4 33.6 15.9 20.3 42.5 26.0 51.8 53.9 26.9 17.8 44.3 67.1 18.3 33.7 6.2 26.1 20.2 55.2 11.2 19.7 20.7 24.7 8.0 13.1 21.4 19.7 24.8 40.6 63.7 24.2 118.0 16.6 16.6 26.3 57.8 49.1 42.3 63.7 63.1 96.7 32.8 34.3 43.4 58.1 46.4 NDUFAF8 C17orf89 ENSG00000224877 "NADH:ubiquinone oxidoreductase complex assembly factor 8" A1L188 17 81239305-81241310 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 264.3" "Cell type enhanced" "Detected in many" "Breast glandular cells: 130.5;Breast myoepithelial cells: 162.6;Distal tubular cells: 279.7;Proximal tubular cells: 337.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA057732 Uncertain Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA057732: AB_2683513" "unprognostic (4.33e-3)" "unprognostic (2.01e-1)" "unprognostic (1.04e-1)" "unprognostic (4.62e-2)" "unprognostic (1.97e-1)" "unprognostic (9.32e-2)" "unprognostic (3.06e-1)" "unprognostic (4.21e-2)" "unprognostic (2.60e-1)" "unprognostic (2.71e-2)" "unprognostic (2.40e-3)" "unprognostic (2.31e-1)" "prognostic unfavorable (1.70e-6)" "unprognostic (5.74e-2)" "unprognostic (2.00e-1)" "unprognostic (1.54e-1)" "unprognostic (1.05e-2)" 47.8 65.1 164.7 28.2 167.7 37.0 40.3 159.5 264.3 32.9 156.0 49.5 21.8 30.4 33.6 45.9 32.0 9.8 110.7 161.5 158.1 68.6 79.1 27.5 26.5 160.1 160.0 33.6 56.3 40.1 54.2 14.5 159.1 44.1 29.4 24.0 36.7 20.2 144.5 33.0 31.6 21.8 161.1 40.4 45.5 30.7 166.1 30.8 38.7 93.0 32.1 45.2 31.6 159.9 142.1 199.9 73.2 72.1 80.4 84.9 79.0 122.1 49.3 82.0 47.1 102.5 60.0 131.6 60.2 86.2 68.2 69.2 69.2 117.4 97.8 33.3 437.1 99.8 222.2 233.3 84.7 139.2 60.8 113.5 140.2 59.3 124.8 87.8 133.0 103.6 132.5 77.3 106.8 130.4 194.6 145.1 41.1 114.6 288.2 121.6 104.8 96.7 89.5 96.1 84.1 107.7 100.5 82.2 126.1 107.2 115.1 127.7 81.5 101.4 154.8 73.2 123.2 110.2 41.1 124.0 91.7 72.8 79.9 41.2 80.1 69.1 73.4 67.1 73.4 103.6 80.4 88.9 82.0 87.6 96.4 94.4 10.3 78.0 76.2 138.0 87.3 77.5 164.7 167.7 159.5 264.3 161.5 158.1 160.1 160.0 159.1 161.1 166.1 159.9 47.9 19.2 17.3 0.0 24.9 0.0 0.0 0.0 0.0 0.0 130.5 162.6 0.0 0.0 9.3 101.2 0.0 120.5 41.0 0.0 279.7 98.1 0.0 59.8 75.1 21.6 0.0 0.0 0.0 124.6 99.0 32.0 0.0 48.1 1.3 73.5 0.0 0.0 129.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.0 0.0 0.0 51.1 0.0 0.0 0.0 0.0 117.4 0.0 0.0 10.6 0.0 0.0 337.8 3.6 0.0 0.0 0.0 40.5 0.0 0.0 0.0 0.0 45.6 23.1 96.8 0.0 0.0 NDUFB11 "ESSS, Np15, NP17.3" ENSG00000147123 "NADH:ubiquinone oxidoreductase subunit B11" Q9NX14 X 47142216-47145038 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Cardiomyopathy, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 717.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030367 Supported Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA030367: AB_10603882" "unprognostic (2.20e-1)" "unprognostic (6.77e-3)" "unprognostic (1.39e-1)" "unprognostic (1.33e-1)" "unprognostic (9.80e-2)" "unprognostic (8.84e-2)" "unprognostic (3.31e-2)" "unprognostic (2.05e-1)" "unprognostic (5.18e-2)" "unprognostic (1.24e-2)" "unprognostic (1.69e-2)" "unprognostic (2.19e-1)" "unprognostic (6.58e-2)" "unprognostic (3.27e-1)" "unprognostic (2.34e-1)" "unprognostic (1.69e-1)" "unprognostic (8.46e-3)" 71.1 133.8 136.0 73.2 141.2 133.2 89.8 147.7 170.6 74.6 158.5 112.5 96.7 54.4 104.6 95.2 84.1 46.2 251.4 140.3 142.3 108.9 164.4 62.2 90.3 144.7 139.0 58.5 158.2 122.9 92.7 62.4 142.0 73.9 98.2 59.2 128.2 79.2 717.0 76.1 96.1 72.2 138.3 74.5 97.8 26.8 146.3 97.8 95.6 378.4 106.3 68.0 66.5 139.3 173.5 297.9 198.7 242.4 173.6 166.1 221.1 125.2 180.5 231.5 224.4 292.6 224.2 218.5 101.8 163.4 222.3 216.2 267.0 157.3 162.0 212.4 663.1 129.5 371.2 271.3 184.7 203.2 188.2 176.9 140.0 191.2 126.8 137.8 193.9 286.8 158.6 282.6 139.3 437.2 269.1 622.5 308.5 219.2 517.2 259.7 210.9 513.6 254.0 210.1 391.2 283.1 231.9 289.2 198.8 259.8 418.2 279.7 130.3 152.7 190.5 239.1 149.0 244.0 270.0 258.5 155.0 138.4 204.2 255.4 410.3 188.6 294.2 306.5 362.1 541.7 408.9 342.6 491.6 470.0 454.3 359.3 84.9 279.7 233.8 636.5 476.3 626.1 136.0 141.2 147.7 170.6 140.3 142.3 144.7 139.0 142.0 138.3 146.3 139.3 154.0 105.8 132.5 16.6 270.9 259.5 252.1 514.5 267.5 89.2 343.7 520.1 236.6 265.9 284.7 290.6 37.5 456.9 227.6 400.0 583.0 314.9 5.2 193.4 229.7 165.6 330.7 246.3 10.2 369.1 429.2 192.1 200.8 267.1 194.1 219.2 203.8 657.2 391.0 55.5 16.7 495.1 333.7 321.7 290.9 16.3 181.7 229.1 265.1 12.2 336.9 238.9 183.4 14.1 25.3 291.8 391.2 176.4 445.1 258.6 360.1 756.8 180.9 109.8 164.3 157.6 248.9 16.8 36.9 358.0 290.5 450.9 228.9 342.6 447.4 334.9 NDUFB6 "B17, CI" ENSG00000165264 "NADH:ubiquinone oxidoreductase subunit B6" O95139 9 32553001-32573184 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 583.9;Distal tubular cells: 534.1;Early spermatids: 889.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044001, HPA053334" Supported Enhanced Mitochondria No No "Cluster 50: Neutrophils - Cellular senescence" "Cluster 39: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Mitochondria "HPA044001: AB_10959448, HPA053334: AB_2682116" "unprognostic (4.09e-1)" "prognostic favorable (3.18e-4)" "unprognostic (1.81e-2)" "unprognostic (1.53e-2)" "unprognostic (1.50e-1)" "unprognostic (1.49e-1)" "unprognostic (1.14e-1)" "unprognostic (6.10e-2)" "unprognostic (1.18e-1)" "unprognostic (1.35e-3)" "unprognostic (1.22e-1)" "unprognostic (1.49e-1)" "prognostic favorable (7.47e-10)" "unprognostic (2.70e-1)" "unprognostic (1.82e-1)" "unprognostic (1.26e-1)" "unprognostic (1.83e-1)" 38.6 50.8 42.7 30.7 45.3 31.0 35.9 47.1 48.1 34.1 42.8 41.8 44.6 38.1 26.8 43.8 36.0 17.6 144.9 44.5 46.5 73.6 66.7 30.5 26.9 44.5 42.9 29.7 31.0 41.8 40.3 22.5 44.6 28.5 29.1 30.7 37.0 22.0 168.0 28.2 43.6 26.7 45.9 28.8 43.5 53.5 44.3 28.7 33.2 101.8 24.5 34.1 33.4 47.1 106.4 63.7 69.6 80.1 46.7 43.0 44.5 69.5 56.5 62.8 68.8 62.8 46.5 78.4 70.5 48.2 65.1 58.8 66.5 76.8 47.0 108.6 106.0 187.2 88.8 65.9 45.2 94.4 46.3 44.8 36.7 56.8 42.9 47.5 57.6 118.4 61.0 86.1 71.9 61.2 128.1 221.2 73.6 90.7 140.1 86.7 58.4 73.1 72.0 39.3 69.7 78.4 80.2 91.1 50.7 52.0 86.3 72.0 51.4 67.9 103.8 75.7 103.8 38.0 77.0 131.5 113.7 65.6 32.7 126.3 97.6 136.1 76.9 94.3 74.5 106.0 81.4 80.0 108.8 89.0 82.3 87.4 302.1 91.9 116.3 152.7 112.4 110.2 42.7 45.3 47.1 48.1 44.5 46.5 44.5 42.9 44.6 45.9 44.3 47.1 69.5 125.0 111.6 15.3 76.2 94.2 106.2 222.9 90.0 44.1 64.6 72.6 583.9 101.5 141.4 108.5 6.2 191.8 69.4 115.8 534.1 172.5 889.5 106.9 86.1 101.0 64.6 196.7 21.8 166.7 143.0 109.5 83.6 86.4 90.5 64.3 74.3 182.2 160.8 18.5 23.8 152.5 209.5 55.0 96.4 146.9 91.6 78.4 160.1 3.7 108.6 115.3 90.6 18.1 21.3 144.4 124.9 89.9 165.7 80.0 201.0 520.3 152.3 56.5 105.2 94.8 151.3 182.0 125.9 139.7 96.7 104.1 81.0 95.6 167.3 103.8 NDUFB8 "ASHI, CI-ASHI" ENSG00000166136 "NADH:ubiquinone oxidoreductase subunit B8" O95169 10 100523740-100530000 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 876.5;Proximal tubular cells: 881.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA003886, HPA065549" Supported Enhanced Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA003886: AB_1079463, HPA065549: " "unprognostic (4.07e-2)" "unprognostic (1.95e-3)" "unprognostic (2.28e-1)" "unprognostic (7.33e-2)" "unprognostic (4.88e-2)" "unprognostic (5.78e-2)" "unprognostic (3.02e-1)" "unprognostic (6.46e-2)" "unprognostic (8.33e-2)" "unprognostic (9.09e-2)" "unprognostic (1.25e-2)" "unprognostic (8.23e-2)" "unprognostic (4.62e-2)" "unprognostic (1.10e-1)" "unprognostic (1.21e-1)" "unprognostic (1.15e-1)" "unprognostic (5.10e-2)" 152.6 199.3 431.2 103.4 439.3 171.5 135.8 427.1 606.3 127.3 416.7 237.8 161.0 145.8 163.0 170.2 132.4 88.0 482.4 444.8 441.9 249.9 262.0 108.6 132.0 438.5 439.4 130.4 115.5 331.0 186.7 83.0 441.9 132.2 145.0 127.1 163.6 135.8 408.9 128.2 147.8 125.5 411.8 133.3 201.0 66.2 442.5 140.6 130.1 512.8 119.9 162.9 132.9 448.3 250.2 419.6 222.3 383.1 159.6 158.8 238.5 168.1 370.9 259.3 278.8 575.4 278.1 260.7 146.4 185.6 189.1 289.5 162.9 269.7 194.5 172.9 417.8 183.9 350.3 465.7 217.6 379.3 302.6 191.6 240.7 249.2 329.3 180.4 283.7 361.1 194.5 159.3 218.4 304.1 369.7 472.9 144.7 324.3 377.9 252.4 237.6 346.1 298.8 281.3 147.9 209.7 122.0 227.4 250.9 147.3 338.2 332.8 185.5 139.5 158.7 151.5 296.8 288.4 286.4 334.8 277.6 398.2 159.3 299.4 530.8 478.1 406.0 558.8 483.1 616.1 498.0 468.1 589.7 546.7 538.1 514.0 122.7 478.0 489.6 655.0 817.6 1113.4 431.2 439.3 427.1 606.3 444.8 441.9 438.5 439.4 441.9 411.8 442.5 448.3 184.8 76.9 132.7 41.8 107.6 0.0 187.1 0.0 12.5 186.4 162.2 210.2 392.9 204.5 48.3 198.6 58.4 333.1 175.8 109.0 876.5 268.1 24.9 105.8 86.3 142.7 105.6 114.3 72.6 264.7 305.1 128.8 35.2 87.1 109.7 112.0 153.8 346.5 399.1 153.1 82.6 171.6 0.0 184.4 0.0 56.0 218.1 142.2 0.0 33.7 231.0 219.5 158.6 40.2 62.3 250.6 191.7 217.4 59.3 203.2 560.2 881.6 85.2 183.5 170.9 117.2 176.0 85.5 83.1 31.5 0.0 307.7 112.9 225.5 237.6 221.5 NDUFB9 "B22, LYRM3, UQOR22" ENSG00000147684 "NADH:ubiquinone oxidoreductase subunit B9" Q9Y6M9 8 124539101-124580648 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1314.9;tongue: 1486.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 2950.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042768 Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA042768: AB_10797508" "unprognostic (1.18e-2)" "unprognostic (2.00e-2)" "unprognostic (1.30e-1)" "unprognostic (2.03e-3)" "unprognostic (8.32e-2)" "unprognostic (9.71e-2)" "unprognostic (3.25e-1)" "unprognostic (1.14e-1)" "unprognostic (4.16e-2)" "unprognostic (3.80e-2)" "unprognostic (1.51e-1)" "unprognostic (3.64e-1)" "prognostic favorable (3.42e-5)" "unprognostic (9.54e-2)" "unprognostic (9.64e-2)" "unprognostic (4.94e-2)" "unprognostic (2.74e-1)" 155.6 158.2 259.0 78.5 263.8 265.2 157.8 281.1 381.2 109.7 245.0 226.4 184.6 129.5 147.4 209.2 126.0 70.4 789.5 257.6 288.7 324.9 325.0 122.9 96.5 279.3 277.8 107.1 209.4 282.9 124.0 81.2 281.5 117.8 191.0 135.8 210.9 115.1 1314.9 149.3 162.9 111.1 253.4 116.8 241.2 204.7 286.2 102.8 154.2 1486.4 104.1 139.9 124.7 274.1 348.2 316.8 236.1 321.2 240.6 204.2 196.0 165.2 189.3 297.4 222.4 417.7 327.6 341.0 421.0 193.6 153.9 385.5 347.3 266.7 279.9 395.8 464.8 831.3 199.6 505.9 320.8 261.8 218.2 239.6 382.1 271.9 587.9 160.1 275.9 241.1 523.7 277.6 243.4 1089.0 415.8 522.7 237.5 1247.0 692.7 276.3 179.9 468.0 400.0 288.8 326.6 255.0 362.4 2950.7 382.8 141.1 407.3 348.2 219.7 172.5 444.1 162.9 399.5 354.8 517.7 392.5 298.6 515.4 233.1 302.2 253.1 136.2 210.5 179.2 209.6 260.9 275.8 237.1 247.5 201.4 269.1 223.9 49.2 188.9 136.1 183.1 346.0 345.8 259.0 263.8 281.1 381.2 257.6 288.7 279.3 277.8 281.5 253.4 286.2 274.1 169.0 125.0 124.8 7.8 147.7 217.8 277.5 448.3 178.7 77.4 247.3 313.0 1005.6 260.2 267.3 286.9 98.0 494.6 119.9 525.0 800.3 338.0 389.8 120.7 100.6 164.1 233.7 227.6 10.5 405.7 296.0 187.9 169.7 109.2 139.4 149.9 167.4 517.7 380.6 37.0 14.9 421.0 488.3 206.0 137.6 865.4 158.8 183.0 247.3 15.9 226.3 144.1 171.0 7.1 18.2 378.1 450.0 152.7 169.1 290.3 584.6 789.7 208.6 91.1 170.9 221.2 511.8 317.6 264.8 377.0 188.4 523.0 155.6 216.0 521.7 315.8 NDUFC1 KFYI ENSG00000109390 "NADH:ubiquinone oxidoreductase subunit C1" O43677 4 139266880-139302551 "Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "heart muscle: 83.5;skeletal muscle: 268.3;tongue: 158.5" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1840.3;Distal tubular cells: 1136.7;Proximal tubular cells: 1449.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044556, HPA062427" Enhanced Approved Mitochondria No No "Cluster 24: B-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA044556: AB_10794402, HPA062427: " "unprognostic (6.07e-2)" "unprognostic (4.61e-3)" "unprognostic (1.76e-2)" "prognostic favorable (8.23e-5)" "unprognostic (7.11e-2)" "unprognostic (1.74e-1)" "unprognostic (1.23e-1)" "unprognostic (1.40e-1)" "unprognostic (7.62e-2)" "unprognostic (3.60e-2)" "unprognostic (3.58e-2)" "unprognostic (1.17e-2)" "prognostic favorable (9.96e-4)" "unprognostic (2.33e-1)" "unprognostic (1.07e-1)" "unprognostic (1.66e-1)" "prognostic favorable (7.25e-4)" 9.5 15.3 19.9 8.0 20.4 9.1 11.0 22.4 28.6 7.4 21.3 18.6 23.8 8.1 14.3 10.5 10.5 5.4 83.5 19.6 20.8 26.7 24.1 8.8 10.1 20.3 21.0 10.0 14.8 22.9 15.8 5.9 21.6 9.7 19.0 23.5 18.9 14.4 268.3 13.2 18.6 7.4 19.5 10.4 17.0 12.7 20.5 8.6 14.8 158.5 11.0 8.6 7.9 22.4 21.4 5.9 19.2 30.8 17.7 22.7 20.5 20.1 13.1 11.1 10.4 13.1 23.7 7.7 7.7 15.5 14.9 10.5 38.6 18.2 15.0 13.0 13.5 11.9 13.5 23.0 18.1 11.2 10.1 24.5 18.2 14.4 21.6 16.8 17.5 17.8 25.3 33.8 11.0 17.8 17.8 32.1 16.3 44.1 11.7 14.9 10.6 52.6 24.6 14.2 14.6 14.7 13.8 23.2 10.5 15.6 23.7 23.2 8.1 24.2 6.4 13.0 13.5 23.2 49.5 18.5 18.9 26.7 13.8 26.2 10.1 13.1 8.5 10.3 11.6 7.1 11.7 11.5 8.9 15.9 10.5 11.4 3.0 10.1 14.2 16.2 18.2 10.8 19.9 20.4 22.4 28.6 19.6 20.8 20.3 21.0 21.6 19.5 20.5 22.4 201.8 89.8 145.7 15.7 95.8 140.2 173.3 402.7 185.0 120.4 240.3 349.6 1840.3 221.6 240.1 439.6 33.3 147.4 71.7 343.0 1136.7 270.3 409.9 333.5 115.5 162.7 221.4 175.2 10.9 336.9 166.2 176.9 158.0 196.8 73.3 151.2 133.5 432.9 225.1 119.5 14.3 340.5 276.7 102.0 65.7 70.9 169.3 115.6 266.8 6.5 185.5 446.6 79.3 8.0 13.3 265.3 355.8 206.5 155.6 173.7 471.7 1449.6 297.1 139.1 98.6 159.3 184.4 439.0 197.4 290.1 179.3 118.1 83.5 224.7 343.7 176.0 NDUFC2 "B14.5b, HLC-1" ENSG00000151366 "NADH:ubiquinone oxidoreductase subunit C2" O95298 11 78068297-78079862 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA038873, HPA056195" Approved Supported Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 39: CACO-2 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" Mitochondria "HPA038873: AB_10673480, HPA056195: AB_2683063" "unprognostic (7.32e-2)" "unprognostic (5.91e-3)" "unprognostic (4.00e-2)" "unprognostic (6.14e-2)" "unprognostic (1.94e-1)" "unprognostic (8.97e-2)" "unprognostic (1.60e-1)" "unprognostic (4.23e-3)" "unprognostic (4.75e-3)" "unprognostic (3.32e-3)" "unprognostic (1.34e-1)" "unprognostic (2.11e-1)" "prognostic favorable (5.00e-5)" "unprognostic (6.32e-2)" "unprognostic (3.01e-1)" "unprognostic (4.18e-2)" "unprognostic (3.61e-3)" 202.3 278.0 118.8 84.5 126.1 126.1 143.0 128.7 150.7 103.0 125.6 143.6 218.4 125.3 68.4 142.6 120.2 108.6 240.7 129.0 145.8 151.1 286.8 100.0 109.1 121.6 117.1 96.2 168.8 186.1 133.5 74.8 124.2 88.7 66.1 59.8 275.1 83.2 487.6 121.9 194.3 63.6 136.8 96.2 130.0 103.0 126.1 73.5 207.0 254.0 62.8 97.1 100.1 136.3 287.6 342.2 183.3 118.8 168.3 105.6 227.2 335.7 190.9 252.4 179.9 910.4 311.8 166.3 583.3 155.8 210.2 293.1 136.1 190.9 99.5 318.8 386.7 183.8 337.4 727.9 270.9 409.7 164.2 147.9 177.8 195.6 75.2 156.0 172.9 158.8 365.3 278.4 137.9 478.7 254.5 722.4 212.4 670.4 415.6 224.5 352.5 570.5 196.4 420.7 261.2 229.0 235.0 499.5 182.3 158.8 391.4 328.2 241.0 256.4 314.9 611.8 297.9 251.5 541.9 400.4 146.4 236.6 251.0 374.5 337.6 354.0 150.1 293.0 138.3 230.8 172.4 163.4 363.5 212.1 144.5 159.8 102.2 225.4 243.0 290.4 202.7 410.9 118.8 126.1 128.7 150.7 129.0 145.8 121.6 117.1 124.2 136.8 126.1 136.3 256.6 166.7 194.7 0.0 106.4 95.5 166.1 443.7 40.5 145.8 346.2 414.0 240.9 243.1 288.2 391.8 66.7 408.8 166.4 206.3 305.2 395.6 311.8 413.8 129.3 183.7 167.9 106.5 0.0 431.5 392.8 165.7 43.3 241.7 153.2 158.1 184.9 856.9 346.2 90.9 0.0 317.9 429.3 174.5 110.7 84.7 215.6 129.4 245.5 0.0 246.7 310.0 175.1 0.0 0.0 456.5 329.1 201.6 102.5 239.0 461.8 454.6 300.0 131.6 236.7 154.5 222.7 384.4 162.1 67.5 114.4 387.1 109.9 226.3 373.2 215.6 NDUFC2-KCTD14 ENSG00000259112 "NDUFC2-KCTD14 readthrough" E9PQ53 11 78016971-78079865 "Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 2.0;Club cells: 1.3;Excitatory neurons: 4.0;Inhibitory neurons: 3.2;Melanocytes: 1.8;Oligodendrocyte precursor cells: 2.5;Oligodendrocytes: 2.4;Respiratory ciliated cells: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CACO-2: 58.3;EFO-21: 47.1" "HPA038873, HPA056195" Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Mitochondria "HPA038873: AB_10673480, HPA056195: AB_2683063" 6.8 6.4 5.3 3.3 5.9 10.6 6.1 6.3 9.4 3.5 3.6 5.1 12.3 1.9 0.9 4.0 7.1 3.6 10.5 6.0 5.9 2.8 5.6 3.6 7.8 5.4 4.8 1.7 2.7 4.8 0.3 2.9 4.9 5.2 2.7 1.3 11.6 11.8 10.9 4.9 8.1 3.6 5.1 2.5 7.2 2.3 4.7 10.4 10.1 17.0 3.8 3.6 0.4 5.8 4.6 12.6 4.2 1.2 4.2 2.7 6.4 12.8 13.1 14.8 10.8 58.3 6.1 6.6 47.1 6.8 11.1 5.8 4.5 11.5 1.9 17.2 18.1 3.5 3.9 42.1 26.7 3.0 15.7 3.4 4.8 11.3 3.0 8.6 11.0 28.9 9.0 3.8 10.7 19.9 18.8 13.3 5.9 36.1 27.0 9.8 5.6 23.9 7.1 8.3 4.9 8.0 12.0 2.6 6.3 1.8 7.0 8.5 5.1 3.7 19.4 17.4 5.0 7.5 16.7 14.4 2.5 7.9 5.8 113.1 104.9 108.0 98.8 82.2 84.2 119.8 98.4 93.8 131.3 103.5 89.8 84.1 31.4 69.4 93.3 213.4 135.7 194.6 5.3 5.9 6.3 9.4 6.0 5.9 5.4 4.8 4.9 5.1 4.7 5.8 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.2 0.5 0.0 0.0 0.0 0.0 0.0 0.1 1.8 1.0 0.0 0.0 0.0 2.5 2.4 0.0 0.2 0.0 0.0 0.1 0.6 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.3 0.0 NDUFS1 CI-75k ENSG00000023228 "NADH:ubiquinone oxidoreductase core subunit S1" P28331 2 206114817-206159509 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 181.7;skeletal muscle: 221.6;tongue: 225.2" "Cell type enriched" "Detected in all" 4 "Cardiomyocytes: 582.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064605, CAB070844" Enhanced Supported Mitochondria NA NA 48000 "Cluster 14: Monocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "CAB070844: , HPA064605: AB_2685297" "prognostic unfavorable (3.85e-4)" "unprognostic (1.76e-1)" "unprognostic (9.22e-3)" "unprognostic (5.01e-2)" "unprognostic (8.63e-3)" "unprognostic (3.75e-1)" "unprognostic (3.72e-2)" "unprognostic (6.18e-2)" "unprognostic (2.30e-2)" "unprognostic (3.28e-1)" "unprognostic (2.00e-2)" "unprognostic (1.28e-1)" "prognostic favorable (1.47e-12)" "unprognostic (1.17e-1)" "unprognostic (1.29e-1)" "unprognostic (4.76e-2)" "unprognostic (4.73e-2)" 27.1 61.6 8.3 13.3 10.8 13.2 23.8 14.9 16.1 19.5 39.7 35.3 29.9 19.3 10.8 36.2 16.3 10.5 181.7 10.7 13.7 48.0 51.8 18.3 12.6 10.1 10.1 14.6 19.2 47.2 20.2 14.4 11.7 15.8 30.0 24.4 27.7 15.6 221.6 26.6 26.1 16.4 9.2 16.8 37.1 20.8 14.2 15.6 17.9 225.2 16.9 22.4 22.4 12.5 28.3 27.6 39.2 28.6 35.8 28.9 45.4 40.4 43.4 66.0 47.6 72.0 32.1 31.7 34.8 50.8 65.5 38.5 52.9 39.2 58.2 14.6 24.9 63.5 65.1 64.9 37.0 46.2 27.5 35.3 22.5 51.9 40.4 29.6 52.3 39.3 69.8 31.1 43.6 35.2 38.5 30.7 36.5 47.2 48.6 38.3 54.7 55.1 54.7 50.7 38.1 29.8 46.7 45.1 67.1 53.3 39.8 44.2 40.1 36.2 32.0 35.8 39.1 29.8 38.4 46.9 36.3 37.5 37.8 14.1 12.9 15.7 12.4 15.2 9.6 9.6 10.8 11.8 14.7 9.0 9.6 11.1 9.2 12.5 22.5 7.8 15.9 9.5 8.3 10.8 14.9 16.1 10.7 13.7 10.1 10.1 11.7 9.2 14.2 12.5 32.4 60.9 33.0 45.1 23.8 16.2 21.7 40.8 30.1 97.1 19.3 14.0 582.5 48.6 42.8 38.6 120.9 48.4 18.8 74.5 93.9 44.2 14.5 49.8 49.8 36.6 51.0 42.0 67.8 28.2 33.7 42.3 48.4 54.5 37.3 42.3 29.3 94.5 34.0 117.8 72.8 47.9 54.9 31.2 10.7 7.0 33.5 27.7 30.2 28.1 37.2 62.7 27.8 45.2 41.6 32.1 46.4 44.8 31.0 19.9 77.8 102.3 53.5 81.5 32.9 55.2 60.8 58.2 49.5 40.8 16.6 52.5 23.7 71.5 69.9 26.6 NDUFS2 CI-49 ENSG00000158864 "NADH:ubiquinone oxidoreductase core subunit S2" O75306 1 161197104-161214723 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 464.8;tongue: 633.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055140, HPA061953" Enhanced Supported Mitochondria NA NA 25000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA055140: AB_2682713, HPA061953: AB_2684646" "unprognostic (2.13e-2)" "unprognostic (2.24e-2)" "unprognostic (8.47e-2)" "unprognostic (7.78e-2)" "unprognostic (9.81e-2)" "unprognostic (2.70e-1)" "unprognostic (1.10e-2)" "unprognostic (1.51e-1)" "unprognostic (3.10e-1)" "unprognostic (1.57e-2)" "unprognostic (3.17e-2)" "unprognostic (1.11e-1)" "prognostic favorable (2.32e-4)" "unprognostic (2.35e-1)" "unprognostic (2.80e-1)" "unprognostic (1.13e-1)" "unprognostic (1.82e-1)" 60.2 98.2 38.7 37.4 41.6 39.5 49.6 46.4 48.8 40.2 76.6 96.5 102.4 41.4 33.4 62.0 52.5 36.8 273.7 40.5 47.5 137.0 177.4 48.5 42.4 49.5 40.7 51.6 47.7 156.5 35.8 41.6 53.1 45.7 101.8 36.2 53.5 49.0 464.8 51.4 81.5 58.6 41.6 43.6 73.3 29.5 47.9 48.3 45.0 633.7 60.1 57.5 40.0 49.2 101.8 129.4 95.2 104.0 115.1 102.8 77.0 85.7 105.8 139.6 107.5 143.9 98.5 108.4 168.1 113.0 81.3 135.9 129.1 131.8 122.1 84.2 108.0 105.9 109.5 136.5 117.7 116.0 105.3 147.2 112.3 121.1 137.2 96.8 160.5 115.4 139.9 72.7 132.5 93.5 81.7 58.4 175.3 288.5 116.5 72.0 83.3 172.0 157.8 109.4 97.2 152.0 93.0 237.0 151.5 116.4 221.7 342.2 108.6 84.5 66.3 65.5 123.7 125.2 172.0 95.1 123.6 109.3 105.4 150.0 159.3 85.7 82.0 193.2 82.6 81.4 86.6 86.3 217.8 68.4 86.6 88.1 86.7 93.5 190.7 128.7 130.8 167.5 38.7 41.6 46.4 48.8 40.5 47.5 49.5 40.7 53.1 41.6 47.9 49.2 70.5 35.3 45.7 30.7 47.1 38.9 52.4 277.8 52.9 74.6 58.9 50.7 232.6 74.4 148.4 77.3 31.3 146.8 47.6 187.5 332.6 184.3 11.3 43.5 57.0 67.5 72.0 78.9 28.0 143.2 111.3 69.7 80.5 41.3 69.7 99.7 65.7 206.5 150.5 92.5 30.1 122.6 242.1 87.8 42.0 7.8 43.5 66.5 83.6 14.0 97.9 57.0 35.0 18.1 48.3 147.7 105.1 33.4 49.5 25.6 221.9 345.5 103.0 57.3 46.0 41.9 176.6 42.0 27.5 68.8 43.3 158.4 50.0 192.0 172.5 57.5 NDUFS4 "AQDQ, CI-18" ENSG00000164258 "NADH:ubiquinone oxidoreductase subunit S4" O43181 5 53560633-53683338 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 397.4" "Cell type enhanced" "Detected in all" "Distal tubular cells: 553.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003884 Supported Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA003884: AB_1079465" "unprognostic (1.25e-1)" "unprognostic (3.61e-3)" "unprognostic (3.44e-2)" "unprognostic (8.11e-2)" "unprognostic (1.46e-1)" "unprognostic (6.73e-3)" "unprognostic (6.93e-2)" "unprognostic (1.11e-1)" "unprognostic (3.93e-1)" "unprognostic (4.38e-1)" "unprognostic (1.72e-2)" "unprognostic (3.11e-1)" "prognostic favorable (3.85e-6)" "unprognostic (9.19e-2)" "unprognostic (1.24e-1)" "unprognostic (1.65e-1)" "unprognostic (1.81e-1)" 94.2 80.6 71.3 37.0 71.8 50.9 99.9 75.1 101.8 82.0 70.6 93.2 83.6 65.0 68.6 80.6 69.5 50.2 190.5 70.3 78.3 137.2 147.9 55.7 45.7 72.3 70.4 101.7 45.4 125.8 58.2 63.0 73.8 65.9 89.6 59.1 63.6 73.6 346.2 76.7 71.9 72.2 75.3 42.9 80.7 37.9 75.1 59.8 74.0 397.4 60.7 71.3 73.0 77.7 118.8 102.9 200.5 119.1 133.9 192.7 167.9 140.7 136.6 153.0 185.8 126.7 151.4 83.9 180.2 121.1 146.3 85.3 72.0 167.9 175.4 77.4 137.2 57.8 97.1 115.6 142.4 141.0 95.8 161.2 190.2 105.8 184.8 167.7 135.1 93.4 50.2 88.5 141.9 110.5 106.7 116.9 60.9 45.3 115.1 126.4 113.1 166.2 165.1 113.0 92.7 99.5 96.4 92.5 175.2 106.8 148.2 145.2 104.4 93.6 98.9 68.7 186.9 67.6 91.5 102.1 99.7 202.7 137.3 19.4 83.9 7.9 49.1 101.8 55.3 72.7 61.9 58.0 121.6 50.3 68.2 70.0 6.8 79.4 108.3 93.8 72.4 68.2 71.3 71.8 75.1 101.8 70.3 78.3 72.3 70.4 73.8 75.3 75.1 77.7 62.1 38.5 56.6 49.0 52.6 125.8 150.4 382.0 56.3 44.8 100.0 119.1 328.4 82.9 170.6 84.6 41.7 168.4 43.2 124.5 553.7 174.1 61.5 65.5 87.7 84.6 90.4 47.1 55.9 167.3 163.3 113.1 47.9 68.7 76.0 146.9 99.2 137.8 144.3 30.3 73.2 135.3 215.7 76.4 127.3 61.5 157.5 70.4 117.4 38.4 161.4 113.6 63.8 52.8 68.4 179.4 153.4 152.7 38.4 95.3 188.7 425.9 112.2 76.0 124.9 145.1 173.4 76.8 75.0 79.3 101.4 179.9 50.0 96.4 171.2 158.2 NDUFS8 "CI-23k, TYKY" ENSG00000110717 "NADH:ubiquinone oxidoreductase core subunit S8" O00217 11 68030617-68036644 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 833.5;Late spermatids: 797.2;Proximal tubular cells: 927.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018524, HPA067429" Enhanced Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA018524: AB_1854355, HPA067429: " "unprognostic (2.90e-1)" "unprognostic (1.41e-3)" "unprognostic (2.41e-1)" "unprognostic (5.20e-2)" "unprognostic (1.37e-1)" "unprognostic (1.30e-3)" "unprognostic (1.36e-1)" "unprognostic (7.75e-2)" "unprognostic (3.15e-1)" "unprognostic (1.77e-2)" "unprognostic (3.81e-2)" "unprognostic (1.81e-1)" "prognostic favorable (3.27e-8)" "unprognostic (2.29e-1)" "unprognostic (1.38e-1)" "unprognostic (2.60e-2)" "unprognostic (9.45e-2)" 99.2 308.4 141.2 38.8 153.2 56.2 87.7 157.2 180.4 73.2 172.3 142.0 81.4 89.2 27.2 115.3 81.3 29.1 468.2 144.2 152.0 188.6 152.0 73.1 42.2 149.6 144.9 68.2 97.7 74.6 130.6 33.6 145.8 118.2 36.7 49.5 96.2 66.7 406.4 93.0 84.4 39.0 142.2 76.9 137.8 104.7 154.0 40.3 101.8 275.5 30.1 94.4 76.0 150.2 152.9 366.4 94.6 137.0 70.9 63.5 132.4 102.3 88.5 155.6 118.9 338.4 159.6 118.4 186.8 85.9 134.6 181.2 108.8 128.4 53.1 139.4 264.9 107.2 217.1 186.3 171.8 99.1 112.1 80.5 126.5 111.1 124.8 82.0 106.2 159.9 110.3 121.1 99.2 358.6 219.2 216.9 125.2 377.7 308.0 154.4 95.9 384.9 192.8 123.3 125.5 102.2 75.7 171.7 392.3 66.5 245.6 105.9 84.1 155.6 133.9 224.8 148.8 165.2 188.5 99.7 252.3 121.8 111.2 84.7 220.1 124.0 182.4 232.0 170.1 183.3 154.6 165.5 309.4 156.3 146.2 164.2 20.7 309.6 131.7 324.3 202.2 232.4 141.2 153.2 157.2 180.4 144.2 152.0 149.6 144.9 145.8 142.2 154.0 150.2 88.7 89.8 90.1 18.6 92.3 85.4 95.5 284.3 104.7 83.4 147.2 156.7 301.9 143.0 164.9 213.3 54.2 279.6 97.8 301.0 833.5 200.8 225.7 101.1 74.8 85.3 205.0 149.8 13.6 199.3 165.9 109.6 147.3 79.7 95.8 156.5 73.5 231.7 276.6 50.5 19.3 277.2 240.1 124.1 108.0 797.2 100.6 128.7 163.7 13.1 187.4 143.6 128.8 12.1 15.4 173.7 194.9 108.0 157.8 118.6 337.1 927.8 120.8 118.7 59.2 81.2 208.6 105.9 72.7 209.7 116.2 172.4 102.7 278.7 318.2 139.1 NDUFV3 CI-10k ENSG00000160194 "NADH:ubiquinone oxidoreductase subunit V3" P56181 21 42879644-42913304 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 88.0" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 770.8;Early spermatids: 502.9;Late spermatids: 1712.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019791, HPA020463, HPA030427, CAB034142" Enhanced Enhanced Mitochondria NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 36: HEL - Hemostasis" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "CAB034142: AB_2298212, HPA019791: AB_1854357, HPA020463: AB_1854358, HPA030427: AB_10603024" "unprognostic (1.62e-1)" "unprognostic (2.17e-3)" "unprognostic (1.31e-1)" "unprognostic (1.04e-1)" "unprognostic (1.10e-1)" "unprognostic (1.11e-2)" "unprognostic (4.69e-1)" "unprognostic (2.97e-2)" "unprognostic (1.05e-1)" "unprognostic (3.13e-1)" "unprognostic (3.85e-3)" "unprognostic (1.54e-1)" "unprognostic (1.45e-1)" "unprognostic (6.56e-2)" "unprognostic (9.30e-3)" "unprognostic (2.14e-1)" "unprognostic (1.94e-1)" 20.5 18.1 9.2 3.2 9.3 6.8 17.5 9.5 8.9 16.6 7.5 24.2 5.1 19.1 7.9 18.9 17.3 2.4 47.2 7.6 8.0 18.0 26.9 13.7 3.1 9.5 9.7 19.1 24.0 7.5 16.6 3.0 9.2 16.3 4.1 7.7 17.3 4.0 88.0 19.0 16.1 3.6 8.4 17.0 19.7 20.9 9.2 2.5 14.9 21.1 3.2 18.4 15.9 10.1 3.3 4.9 9.1 8.1 7.9 5.0 10.4 6.6 4.2 5.2 3.4 10.6 6.2 4.9 4.2 4.1 11.7 5.4 8.8 8.1 3.5 2.8 7.4 20.1 8.7 9.0 9.4 6.0 7.8 8.0 8.2 6.9 12.0 4.2 6.1 5.6 13.5 7.3 5.6 10.5 3.7 6.2 10.2 15.7 6.9 4.6 5.3 12.3 9.5 7.5 5.8 4.7 9.0 10.3 4.8 4.4 10.2 4.6 8.9 3.2 3.0 4.4 4.8 12.1 7.1 3.5 5.7 7.7 4.6 3.1 5.7 3.8 2.8 7.1 2.4 2.9 2.4 2.2 5.0 3.5 2.9 2.8 3.3 4.4 6.6 4.4 2.7 2.8 9.2 9.3 9.5 8.9 7.6 8.0 9.5 9.7 9.2 8.4 9.2 10.1 42.8 54.5 46.7 14.4 36.5 19.9 53.7 97.7 24.5 81.2 64.9 65.7 770.8 92.9 58.6 90.1 68.8 57.5 32.5 89.3 230.9 86.5 502.9 84.5 64.9 48.1 78.3 112.4 19.4 101.5 59.5 57.2 55.5 56.9 31.6 45.5 68.2 334.5 114.4 57.2 22.1 114.8 87.5 88.3 38.1 1712.0 66.5 62.3 37.4 17.8 86.4 88.7 49.4 15.6 19.5 98.6 80.9 62.4 39.0 109.3 176.4 372.6 85.9 104.7 72.3 54.0 66.1 243.5 77.1 50.0 23.4 89.9 29.9 83.8 95.4 65.3 NF1 ENSG00000196712 "Neurofibromin 1" P21359 17 31094927-31382116 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "GTPase activation" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 254.0;Excitatory neurons: 325.3;Inhibitory neurons: 412.5;Oligodendrocyte precursor cells: 428.2;Oligodendrocytes: 317.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045502 Uncertain Approved Mitochondria No No "Cluster 20: T-cells - T-cell receptor" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA045502: AB_2679352" "unprognostic (6.69e-2)" "unprognostic (8.73e-2)" "unprognostic (8.26e-2)" "unprognostic (1.76e-2)" "unprognostic (2.06e-2)" "unprognostic (2.79e-2)" "unprognostic (1.38e-1)" "unprognostic (1.07e-1)" "unprognostic (1.11e-1)" "unprognostic (1.30e-2)" "unprognostic (3.14e-2)" "unprognostic (3.88e-2)" "unprognostic (1.00e-2)" "unprognostic (2.19e-1)" "unprognostic (1.53e-1)" "unprognostic (1.40e-1)" "unprognostic (3.70e-1)" 7.4 8.4 8.9 7.1 10.7 3.4 11.5 13.2 12.2 10.0 1.6 8.5 6.8 10.2 10.0 6.1 9.0 8.0 11.3 9.7 11.7 12.0 9.4 7.3 7.7 11.7 9.2 13.5 10.4 15.9 7.8 12.4 9.1 9.5 8.8 20.9 9.1 9.5 8.1 7.4 7.5 8.7 8.2 7.1 8.2 10.0 11.8 13.5 19.5 10.6 7.8 10.4 6.8 14.4 15.8 20.3 24.2 13.1 20.1 25.8 12.2 13.4 24.1 19.5 21.8 18.4 10.5 15.2 3.8 25.1 22.9 26.8 22.2 18.7 32.6 7.5 14.1 13.4 18.8 9.5 14.2 24.4 10.6 20.7 11.8 20.8 25.1 21.8 9.5 15.7 19.8 14.8 18.8 12.4 20.4 8.8 7.1 9.7 6.8 15.8 36.8 12.3 14.7 22.5 10.0 14.9 25.4 8.3 13.8 16.8 25.0 15.3 14.1 15.3 21.5 18.8 5.1 13.2 6.9 16.3 12.6 10.0 16.2 4.4 0.3 0.6 1.5 0.1 1.0 1.4 2.8 2.5 0.4 1.2 2.0 2.0 0.7 0.7 0.3 0.4 5.9 0.6 8.9 10.7 13.2 12.2 9.7 11.7 11.7 9.2 9.1 8.2 11.8 14.4 30.9 32.1 31.1 254.0 18.3 38.6 48.1 38.9 31.9 62.7 33.7 24.9 43.9 41.5 29.8 40.5 137.6 57.5 23.8 37.8 23.5 27.1 210.4 27.4 39.4 35.8 19.8 9.7 325.3 22.5 26.6 39.1 39.3 45.8 10.8 44.0 33.2 35.7 22.5 70.7 412.5 24.3 38.7 27.6 34.1 94.6 37.3 28.2 21.4 215.5 20.9 47.5 21.6 428.2 317.4 33.3 43.0 50.4 30.8 54.2 32.1 28.6 36.9 62.8 46.0 51.9 43.3 30.5 28.7 19.8 34.0 49.3 19.8 36.1 27.4 64.5 NHLRC4 ENSG00000257108 "NHL repeat containing 4" P0CG21 16 567005-569495 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 11.7;kidney: 10.5" "Cell type enhanced" "Detected in some" "Collecting duct cells: 23.9;Endometrial ciliated cells: 23.3;Erythroid cells: 11.8;Leydig cells: 8.1;Respiratory ciliated cells: 18.1;Theca cells: 12.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "eosinophil: 2.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 3.3;HMC-1: 9.6;REH: 2.6;RPMI-8226: 4.3" "Low region specificity" "Detected in single" HPA077301 Approved Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 3: HMC-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" Mitochondria "HPA077301: " "unprognostic (7.95e-2)" "unprognostic (5.87e-2)" "unprognostic (4.28e-3)" "unprognostic (2.53e-2)" "unprognostic (1.08e-1)" "unprognostic (5.95e-3)" "unprognostic (2.21e-1)" "unprognostic (2.48e-1)" "unprognostic (2.28e-1)" "unprognostic (3.34e-1)" "unprognostic (2.20e-3)" "unprognostic (1.19e-2)" "unprognostic (1.16e-2)" "unprognostic (5.16e-3)" "unprognostic (1.25e-1)" "unprognostic (1.67e-2)" "unprognostic (1.60e-1)" 0.8 5.4 0.6 0.7 0.5 2.9 1.2 0.8 0.5 1.8 2.1 0.9 1.0 1.1 2.1 0.3 11.7 0.9 0.9 0.7 1.0 10.5 0.2 2.0 1.9 2.8 3.3 3.0 0.2 3.2 1.1 0.6 1.7 1.4 0.2 0.0 2.2 2.4 0.5 0.3 1.5 0.3 2.3 3.8 0.6 2.7 0.8 2.4 0.4 0.2 0.6 0.7 0.6 0.6 0.0 0.0 0.4 0.0 0.0 0.2 0.1 0.0 0.6 0.1 0.1 0.1 0.1 0.5 0.4 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.1 3.3 0.0 0.8 0.7 0.2 9.6 1.9 0.0 0.1 0.2 0.0 0.2 0.6 1.0 1.1 0.0 0.0 0.3 2.5 0.2 0.0 0.0 2.6 0.0 4.3 0.2 0.1 0.0 0.9 0.0 0.0 0.3 0.0 0.4 0.5 0.5 0.0 0.0 0.0 0.0 1.5 1.4 0.7 0.0 0.1 0.2 0.0 0.2 2.3 0.1 0.0 0.2 0.4 0.5 0.2 0.2 0.2 0.5 0.3 0.0 0.3 0.1 1.7 0.5 0.3 0.6 0.5 0.8 0.5 0.7 1.0 2.8 3.3 1.7 2.3 0.8 0.6 1.6 0.0 0.0 0.3 1.2 0.0 0.5 0.8 0.6 0.1 1.9 1.4 0.2 0.0 2.2 23.9 0.0 0.2 1.8 0.1 0.0 0.0 0.0 23.3 1.1 1.0 0.0 11.8 0.1 0.2 0.0 2.3 0.0 1.0 0.0 0.4 1.1 0.0 1.7 0.0 0.5 0.2 2.0 0.6 0.9 0.4 8.1 0.5 0.0 1.0 0.2 1.5 1.0 0.0 0.0 0.0 0.0 4.5 0.9 0.3 0.3 0.1 18.1 0.1 6.6 0.1 2.0 0.1 0.1 0.0 0.1 0.0 0.7 12.7 0.2 0.3 NIPSNAP2 GBAS ENSG00000146729 "Nipsnap homolog 2" O75323 7 55951793-56000181 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "heart muscle: 266.5;skeletal muscle: 645.5;tongue: 784.2" "Cell type enhanced" "Detected in many" "Distal tubular cells: 226.9;Endometrial ciliated cells: 107.5;Proximal tubular cells: 106.8" "Cancer enhanced" "Detected in all" "glioma: 73.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A-431: 301.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063084 Enhanced Supported Mitochondria NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA063084: AB_2684938" "unprognostic (6.88e-2)" "unprognostic (6.53e-3)" "unprognostic (8.20e-3)" "unprognostic (4.95e-2)" "unprognostic (5.79e-2)" "unprognostic (1.53e-3)" "unprognostic (5.95e-3)" "unprognostic (1.02e-1)" "unprognostic (1.77e-1)" "unprognostic (6.38e-3)" "unprognostic (2.47e-1)" "unprognostic (1.31e-1)" "prognostic favorable (3.02e-8)" "unprognostic (1.79e-2)" "unprognostic (1.88e-1)" "unprognostic (6.65e-3)" "unprognostic (3.59e-1)" 61.2 70.3 46.0 25.4 48.4 39.2 59.0 47.2 56.9 45.4 50.8 56.0 31.4 41.1 36.6 49.0 50.4 27.5 266.5 45.1 49.5 63.8 14.5 36.9 26.4 45.2 48.7 34.7 49.2 70.4 27.1 31.0 47.1 53.4 53.8 27.6 79.2 55.9 645.5 21.9 32.4 46.6 49.0 26.1 46.5 20.5 50.0 40.1 86.5 784.2 28.7 40.8 26.0 47.6 301.3 52.3 67.5 112.6 38.7 65.8 33.1 24.7 58.2 69.7 53.5 36.5 64.9 43.8 40.5 46.6 67.5 39.1 51.4 52.2 68.7 27.9 75.4 31.1 27.6 46.9 54.6 68.0 30.2 60.3 78.4 23.8 64.5 79.1 74.6 62.2 56.2 41.9 54.8 13.4 68.1 70.4 66.7 66.5 52.3 68.0 31.3 90.8 94.6 46.7 71.7 80.8 56.2 67.0 78.3 53.0 129.9 72.3 43.9 31.7 47.4 11.3 52.0 34.1 30.9 81.2 35.1 41.9 95.7 48.2 86.6 39.1 22.6 86.4 27.2 37.7 28.8 23.8 91.7 37.0 34.2 25.2 15.3 41.9 69.1 38.1 37.9 72.4 46.0 48.4 47.2 56.9 45.1 49.5 45.2 48.7 47.1 49.0 50.0 47.6 45.4 51.3 57.7 0.0 10.3 0.0 0.0 0.0 0.0 0.0 80.4 63.8 0.0 0.0 43.3 62.5 0.0 76.0 20.1 0.0 226.9 74.8 0.0 107.5 56.1 22.1 0.0 0.0 0.0 57.2 56.4 23.4 0.0 57.6 16.4 64.7 0.0 0.0 88.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.6 0.0 0.0 39.8 0.0 0.0 0.0 0.0 46.2 0.0 0.0 5.2 0.0 0.0 106.8 88.2 0.0 0.0 0.0 26.7 0.0 0.0 0.0 0.0 51.4 12.3 74.0 0.0 0.0 NLGN2 KIAA1366 ENSG00000169992 "Neuroligin 2" Q8NFZ4 17 7404874-7419860 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 32.7;Horizontal cells: 57.2;Oligodendrocyte precursor cells: 45.8;Sertoli cells: 32.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 42.2" "Low region specificity" "Detected in all" "HPA055321, HPA069278" Enhanced Approved Mitochondria NA NA 14000 "Cluster 72: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" Mitochondria "HPA055321: AB_2682783, HPA069278: AB_2686105" "unprognostic (1.31e-1)" "unprognostic (1.87e-2)" "unprognostic (4.35e-3)" "unprognostic (2.58e-1)" "unprognostic (1.12e-1)" "unprognostic (9.79e-3)" "unprognostic (2.92e-1)" "unprognostic (1.56e-1)" "unprognostic (6.50e-2)" "unprognostic (2.24e-2)" "unprognostic (5.58e-3)" "unprognostic (1.23e-2)" "prognostic unfavorable (3.44e-4)" "unprognostic (1.69e-1)" "unprognostic (2.85e-1)" "unprognostic (5.50e-3)" "unprognostic (1.81e-2)" 25.0 18.1 25.6 4.8 26.0 0.4 21.2 13.5 25.3 61.9 0.0 36.4 1.5 57.9 7.5 10.2 46.1 7.7 18.2 23.7 18.6 16.6 9.3 16.7 2.7 18.1 15.2 66.6 9.4 7.6 23.7 3.8 13.9 29.7 2.2 15.5 13.6 9.0 11.7 14.8 16.6 12.3 12.1 16.9 16.3 6.7 20.9 0.8 14.2 2.4 1.8 31.2 32.4 19.0 7.1 9.8 42.2 24.4 12.6 18.0 1.0 11.6 18.2 19.4 17.9 2.2 2.4 0.1 5.5 16.4 11.4 3.9 7.9 4.9 10.0 10.8 7.9 3.1 9.6 1.6 6.3 3.1 10.4 14.1 3.8 15.9 2.4 29.1 6.5 3.9 2.9 5.6 7.9 6.6 1.4 3.1 7.2 0.4 4.7 12.9 5.0 1.4 5.6 1.5 0.6 17.0 5.3 2.5 3.0 8.3 6.9 0.4 9.0 16.6 20.6 10.5 5.7 6.4 2.2 1.2 17.3 2.8 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.6 26.0 13.5 25.3 23.7 18.6 18.1 15.2 13.9 12.1 20.9 19.0 5.4 0.0 2.6 25.8 0.5 4.7 3.1 3.3 7.4 32.7 5.6 5.2 11.0 5.7 1.0 0.0 8.4 0.4 3.4 0.1 0.0 2.7 2.0 1.5 25.3 6.8 0.0 0.0 23.5 0.4 6.3 11.5 0.5 2.3 0.0 5.8 6.1 3.2 1.0 57.2 24.8 0.3 0.0 0.8 1.8 2.9 17.1 0.7 1.8 5.6 0.6 22.3 0.0 45.8 13.6 1.6 0.0 22.2 0.3 3.0 0.1 1.3 0.8 16.8 32.9 10.8 10.7 0.5 1.1 1.2 3.8 0.8 1.7 4.3 0.3 1.2 NLN "AGTBP, KIAA1226" ENSG00000123213 Neurolysin Q9BYT8 5 65722205-65871725 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 52.8;Excitatory neurons: 58.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.6;intermediate monocyte: 3.4;myeloid DC: 2.2;non-classical monocyte: 2.3" "Group enriched" "Detected in many" 5 "dendritic cells: 2.2;monocytes: 3.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031862 Approved Approved Mitochondria Yes No 64000 "Cluster 7: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA031862: AB_10600827" "unprognostic (5.91e-3)" "unprognostic (4.52e-2)" "unprognostic (1.34e-3)" "unprognostic (4.37e-2)" "unprognostic (3.85e-1)" "unprognostic (1.45e-2)" "unprognostic (7.29e-3)" "unprognostic (3.24e-2)" "unprognostic (3.19e-1)" "unprognostic (3.58e-1)" "prognostic unfavorable (7.51e-4)" "unprognostic (1.27e-1)" "prognostic favorable (5.58e-7)" "unprognostic (1.52e-2)" "unprognostic (1.98e-1)" "unprognostic (1.29e-1)" "unprognostic (6.18e-3)" 2.2 1.0 3.8 2.4 3.9 1.5 3.7 2.9 5.3 1.8 1.6 3.6 1.1 2.7 2.4 2.5 1.5 1.2 2.6 3.8 3.6 3.9 9.9 1.7 1.7 3.9 3.4 1.8 2.5 1.5 0.9 2.4 4.0 2.6 3.2 2.5 1.9 1.1 8.9 2.8 2.7 2.7 3.3 1.3 4.0 1.1 3.9 0.9 2.7 6.5 2.0 2.7 1.5 4.8 13.3 12.5 7.2 12.0 9.0 15.3 14.5 13.1 5.5 7.6 8.2 7.2 7.7 18.8 16.1 15.8 15.1 10.3 9.5 20.2 13.1 5.6 6.4 5.2 8.7 18.5 7.7 12.0 3.0 11.7 10.8 10.5 12.4 6.3 21.7 8.3 11.4 3.9 16.5 10.2 8.3 10.8 22.2 6.7 3.6 9.6 15.3 29.9 12.6 5.9 22.3 11.5 10.6 10.7 11.0 19.4 12.9 14.1 12.5 5.0 5.9 7.4 10.0 3.3 7.1 8.2 7.7 23.2 7.7 0.1 2.6 0.1 0.1 3.4 0.1 0.4 0.2 0.1 2.2 0.4 0.3 0.2 0.3 0.5 2.3 0.1 0.0 1.0 3.8 3.9 2.9 5.3 3.8 3.6 3.9 3.4 4.0 3.3 3.9 4.8 5.9 6.4 2.8 19.6 4.0 5.7 9.0 6.2 8.6 2.4 10.1 8.9 14.5 7.2 8.5 12.9 4.2 5.3 0.6 52.8 5.9 17.8 0.3 7.4 12.9 8.3 1.8 9.0 58.9 14.5 14.0 7.1 20.4 20.9 15.2 16.2 4.6 32.4 28.8 5.0 32.2 5.8 6.1 22.9 8.9 0.4 4.4 13.5 1.8 5.6 17.9 13.1 2.1 22.6 44.5 30.2 35.9 2.2 4.9 16.5 32.3 22.4 3.1 4.7 0.0 19.7 8.1 2.1 5.2 15.3 5.3 2.9 2.3 15.8 8.2 6.1 NLRP4 "CLR19.5, CT58, FLJ32126, NALP4, PAN2, PYPAF4, RNH2" ENSG00000160505 "NLR family pyrin domain containing 4" Q96MN2 19 55836540-55881855 "Predicted intracellular proteins" "Inflammatory response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "lymphoid tissue: 5.0;testis: 7.0" "Cell type enhanced" "Detected in some" "Early spermatids: 17.6;Late spermatids: 5.1;Spermatogonia: 3.3" "Cancer enriched" "Detected in single" 7 "testis cancer: 1.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "Daudi: 82.3" "Not detected" "Not detected" HPA062128 Approved Mitochondria NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Mitochondria "HPA062128: " "unprognostic (2.48e-1)" "unprognostic (7.01e-2)" "unprognostic (4.21e-2)" "unprognostic (1.34e-2)" "unprognostic (3.11e-1)" "unprognostic (1.81e-1)" "unprognostic (2.36e-3)" "unprognostic (3.72e-2)" "unprognostic (2.36e-1)" "unprognostic (3.89e-1)" "unprognostic (2.02e-1)" "unprognostic (1.17e-1)" "unprognostic (2.71e-2)" 0.1 0.0 0.5 0.6 0.6 0.0 0.0 0.7 1.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.0 1.6 0.8 0.6 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 7.0 0.7 0.1 0.0 0.0 5.0 0.0 0.0 1.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 82.3 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.6 0.4 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.7 1.0 0.7 0.5 0.8 0.6 0.8 0.6 0.7 1.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.1 5.1 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NME4 "NDPKD, nm23-H4, NM23H4" ENSG00000103202 "NME/NM23 nucleoside diphosphate kinase 4" O00746 16 396725-410367 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid transport, Nucleotide metabolism, Transport" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 250.5;Erythroid cells: 311.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB045997, HPA072588" Approved Supported Mitochondria Yes No "Cluster 26: Non-specific - Mitochondria" "Cluster 15: Liver - Metabolism" "Cluster 14: REH - Unknown function" "Cluster 33: Fibroblasts - ECM organization" Mitochondria "CAB045997: AB_11126630, HPA072588: AB_2686538" "unprognostic (3.27e-1)" "prognostic unfavorable (6.53e-4)" "unprognostic (3.70e-2)" "unprognostic (7.16e-3)" "unprognostic (1.32e-1)" "unprognostic (2.00e-1)" "unprognostic (4.40e-2)" "unprognostic (4.46e-3)" "unprognostic (1.98e-1)" "unprognostic (3.12e-1)" "unprognostic (3.74e-2)" "unprognostic (7.79e-3)" "prognostic unfavorable (1.61e-7)" "unprognostic (3.78e-2)" "unprognostic (2.16e-1)" "unprognostic (6.04e-2)" "unprognostic (3.08e-1)" 89.3 136.1 78.3 26.2 75.6 127.7 72.9 73.5 101.5 88.1 77.3 192.9 21.9 79.5 55.7 50.1 89.1 41.2 101.2 76.4 81.7 60.4 175.2 48.3 21.1 88.6 77.9 86.8 43.7 56.7 64.3 30.8 79.8 143.7 23.5 11.1 70.4 81.9 34.7 31.4 59.7 51.9 78.6 43.8 97.7 44.7 80.3 29.3 51.6 27.2 15.8 145.6 64.3 73.6 1.0 305.4 265.6 366.7 104.0 181.0 59.5 143.6 170.4 211.8 180.6 205.4 176.2 3.0 105.8 230.2 76.9 3.9 145.0 153.9 62.0 126.5 218.7 151.9 40.2 279.9 195.7 111.0 53.1 234.7 79.8 130.5 12.8 152.2 137.6 210.7 159.6 25.8 160.4 255.4 98.5 139.2 271.8 76.1 67.8 485.8 59.3 79.0 150.6 1.2 77.7 419.2 36.8 2.7 139.9 97.2 178.3 257.5 174.0 149.7 216.8 101.8 36.8 2.7 2.0 83.1 65.8 19.8 177.2 12.9 13.3 39.8 14.9 11.9 12.7 27.6 14.4 16.3 17.6 29.9 26.0 13.4 4.2 2.5 10.6 58.3 0.9 10.7 78.3 75.6 73.5 101.5 76.4 81.7 88.6 77.9 79.8 78.6 80.3 73.6 52.2 0.0 13.9 18.6 40.6 32.2 56.3 49.0 40.9 15.2 116.6 135.8 44.5 52.9 25.1 58.8 2.1 71.7 45.7 19.3 250.5 116.5 5.0 30.8 113.3 55.3 45.1 311.8 16.8 40.3 26.1 87.3 29.6 59.8 29.9 199.9 55.6 132.2 131.2 8.4 21.1 38.6 26.4 46.5 68.6 21.6 89.2 35.4 62.2 10.3 46.5 45.9 19.6 10.1 3.6 58.3 23.8 94.8 34.5 121.8 9.0 75.5 7.9 5.6 52.6 40.1 105.8 1.7 32.7 38.6 24.6 21.8 26.2 89.4 54.9 60.9 NMNAT3 PNAT3 ENSG00000163864 "Nicotinamide nucleotide adenylyltransferase 3" Q96T66 3 139560180-139678017 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 50.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 567.3;Alveolar cells type 2: 566.9;Club cells: 217.6;granulocytes: 278.8;Late spermatids: 223.3;Respiratory ciliated cells: 250.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 31.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA039077, HPA057402" Approved Supported Mitochondria NA NA "Cluster 11: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 29: U-266 - Adaptive immune response" "Cluster 11: Alveolar cells - Smell perception" Mitochondria "HPA039077: AB_2676336, HPA057402: AB_2683427" "unprognostic (9.45e-3)" "prognostic favorable (9.67e-4)" "unprognostic (2.29e-1)" "unprognostic (1.56e-3)" "unprognostic (2.33e-2)" "unprognostic (2.33e-1)" "unprognostic (2.77e-3)" "unprognostic (6.22e-2)" "unprognostic (9.69e-2)" "unprognostic (1.92e-1)" "prognostic favorable (7.29e-5)" "unprognostic (4.57e-2)" "prognostic favorable (1.95e-5)" "unprognostic (4.13e-2)" "unprognostic (1.63e-1)" "unprognostic (1.44e-1)" "unprognostic (3.07e-1)" 7.5 7.4 17.7 4.9 26.7 19.3 8.3 46.5 45.4 6.7 8.2 6.9 9.2 9.4 8.1 5.4 13.6 5.4 11.6 21.5 10.9 9.2 6.6 4.3 4.8 8.6 5.3 20.1 12.0 8.9 5.5 2.2 15.1 6.5 7.5 30.6 9.3 5.5 29.6 19.0 7.8 5.6 2.5 5.4 5.6 11.3 14.6 3.0 7.6 20.3 5.3 5.5 6.8 50.1 9.2 3.6 4.0 4.6 0.9 0.9 5.0 3.7 0.4 0.6 0.5 5.1 6.4 5.9 10.8 0.7 4.3 4.5 3.0 1.2 0.7 5.8 5.3 31.4 9.1 6.9 2.4 5.6 5.5 1.4 7.8 1.0 1.7 9.3 0.5 3.6 5.0 13.1 0.6 6.2 5.3 4.6 9.0 16.5 3.7 4.4 4.5 4.3 1.2 6.3 9.2 5.4 9.2 4.8 3.3 7.3 12.6 15.6 5.6 5.7 12.6 7.2 5.5 23.1 11.0 4.2 3.8 9.0 5.4 11.4 3.6 2.2 2.8 3.4 1.9 2.7 2.4 2.4 2.8 4.5 3.4 3.6 7.0 4.0 3.4 2.9 1.6 1.7 17.7 26.7 46.5 45.4 21.5 10.9 8.6 5.3 15.1 2.5 14.6 50.1 5.5 567.3 566.9 34.9 1.9 4.1 6.3 6.6 6.2 2.7 8.2 7.1 9.7 8.6 217.6 9.2 4.2 0.4 0.8 2.3 11.7 3.3 128.2 2.1 2.4 38.8 6.7 27.1 37.2 3.1 0.2 38.3 3.1 1.7 278.8 9.7 2.5 2.7 2.0 1.7 26.0 6.5 8.2 4.1 2.9 223.3 7.8 31.8 7.2 12.2 1.8 12.3 0.0 46.8 16.9 0.8 2.9 6.4 0.7 6.1 3.5 16.1 250.6 18.5 6.6 13.2 3.8 67.1 3.5 4.4 9.7 0.1 21.5 5.9 10.6 4.8 NOA1 "C4orf14, hAtNOS1, hNOA1, MGC3232, MTG3" ENSG00000084092 "Nitric oxide associated 1" Q8NC60 4 56963350-56977606 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035838, HPA035839" Approved Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" Mitochondria "HPA035838: AB_10669531, HPA035839: AB_10669658" "unprognostic (6.61e-2)" "unprognostic (1.66e-1)" "unprognostic (1.65e-3)" "unprognostic (5.19e-2)" "unprognostic (9.06e-2)" "unprognostic (1.49e-2)" "unprognostic (2.04e-2)" "unprognostic (1.29e-1)" "unprognostic (1.75e-1)" "unprognostic (1.01e-3)" "unprognostic (3.64e-2)" "unprognostic (1.33e-1)" "prognostic favorable (2.38e-4)" "unprognostic (8.97e-2)" "unprognostic (6.87e-2)" "unprognostic (1.79e-2)" "unprognostic (4.27e-2)" 10.4 8.8 6.9 10.3 7.9 17.5 15.5 8.2 7.6 12.3 7.8 15.8 19.5 11.1 11.3 11.3 16.8 9.6 10.9 7.2 6.8 11.0 8.6 9.1 16.7 7.5 6.8 15.1 22.9 10.9 4.1 8.3 7.8 11.3 14.2 6.9 16.0 10.7 21.8 17.8 14.7 10.2 7.4 11.6 13.3 6.7 6.9 17.6 12.0 16.1 17.5 11.4 8.5 8.7 18.9 17.2 12.3 21.9 22.7 40.5 33.9 14.6 26.5 16.7 16.8 30.3 34.4 67.8 24.5 12.5 13.1 19.7 24.2 26.2 15.8 12.4 30.8 16.8 14.2 33.0 17.7 30.8 17.4 37.7 31.4 15.4 26.7 34.9 28.5 28.6 28.9 22.0 22.8 27.9 44.3 41.2 16.2 36.0 26.4 30.5 13.2 25.4 24.1 28.1 28.5 24.3 15.1 60.2 22.5 15.8 26.9 21.6 18.4 13.0 31.2 15.8 27.3 29.5 13.2 34.5 13.2 19.4 17.1 14.2 33.1 16.7 26.2 31.3 40.8 45.6 40.1 33.8 39.4 35.7 48.3 40.6 8.0 48.1 28.3 30.3 52.0 35.8 6.9 7.9 8.2 7.6 7.2 6.8 7.5 6.8 7.8 7.4 6.9 8.7 10.3 3.2 5.8 5.2 21.3 25.4 20.9 31.4 35.9 6.6 24.7 20.6 16.2 17.2 18.4 7.3 4.2 31.5 19.8 10.6 19.6 19.0 27.0 30.9 14.3 13.2 17.5 27.3 6.8 22.8 32.7 15.6 15.3 15.2 8.2 19.1 10.4 5.1 17.8 1.7 6.8 20.6 16.2 20.3 16.2 12.5 16.1 14.2 12.4 1.9 26.9 10.0 25.7 5.0 8.0 16.9 20.3 23.3 14.7 16.7 31.4 14.8 25.0 9.4 13.1 15.5 19.8 13.0 8.9 24.4 24.7 27.9 18.2 30.8 34.5 20.6 NOD1 "CARD4, CLR7.1, NLRC1" ENSG00000106100 "Nucleotide binding oligomerization domain containing 1" Q9Y239 7 30424527-30478784 "Human disease related genes, Predicted intracellular proteins" "Apoptosis, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 19.3;Microglial cells: 26.2" "Cancer enhanced" "Detected in all" "thyroid cancer: 11.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA074367 Approved Mitochondria NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Mitochondria "HPA074367: AB_2686683" "unprognostic (2.58e-1)" "unprognostic (1.56e-2)" "unprognostic (9.73e-2)" "unprognostic (8.09e-3)" "unprognostic (2.07e-2)" "unprognostic (1.70e-1)" "unprognostic (1.01e-3)" "unprognostic (6.63e-2)" "unprognostic (2.26e-1)" "unprognostic (2.74e-1)" "unprognostic (8.78e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (6.68e-4)" "unprognostic (6.62e-2)" "unprognostic (1.46e-1)" "prognostic favorable (1.95e-4)" "unprognostic (2.64e-1)" 10.6 2.9 3.0 8.8 3.2 6.8 9.5 2.5 2.6 5.3 4.6 5.3 2.2 6.1 2.6 4.7 6.5 5.4 7.3 2.4 3.2 3.9 2.2 11.9 6.1 7.6 4.9 10.3 1.8 2.7 2.9 12.2 4.7 4.0 4.3 0.6 6.2 3.2 4.0 5.9 5.4 7.3 3.6 11.1 4.8 1.9 5.6 3.5 10.8 4.0 5.0 7.3 5.0 2.8 4.8 2.5 3.5 10.5 2.2 10.3 5.3 3.3 2.3 5.5 7.0 2.2 5.7 6.9 3.8 4.2 6.1 11.2 3.5 5.8 3.7 3.6 3.0 9.7 7.7 2.2 2.8 4.3 7.0 9.6 2.5 3.5 3.0 4.9 18.3 10.1 5.2 2.4 5.0 2.8 6.2 7.7 4.1 5.3 4.5 7.4 4.0 6.3 1.8 3.8 0.6 12.4 4.2 10.7 3.7 4.8 3.6 9.6 7.7 4.8 7.6 6.0 4.5 2.2 8.0 0.3 3.5 15.1 5.1 13.7 3.7 13.5 8.1 5.0 8.9 7.5 5.5 5.3 3.3 10.9 4.9 4.0 2.8 8.5 6.6 8.0 4.8 2.6 3.0 3.2 2.5 2.6 2.4 3.2 7.6 4.9 4.7 3.6 5.6 2.8 19.3 3.2 15.1 7.2 6.6 0.8 0.5 1.0 5.2 2.4 2.9 2.9 4.9 1.5 5.0 5.5 0.0 5.0 6.7 4.5 0.0 1.3 0.2 4.4 1.7 12.0 0.0 3.4 5.3 2.1 2.3 8.2 1.1 4.6 2.5 7.8 13.6 1.3 4.6 0.0 1.4 5.5 2.0 3.1 3.7 0.0 0.6 4.3 5.4 26.2 4.0 0.6 6.2 2.5 1.1 1.7 1.7 1.9 3.1 0.2 1.6 0.5 2.9 0.2 0.0 2.5 5.6 0.0 0.6 5.4 1.8 1.5 5.3 1.0 5.6 0.8 NUBPL "C14orf127, FLJ12660, huInd1, IND1" ENSG00000151413 "Nucleotide binding protein like" Q8TB37 14 31489956-31861224 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 68.2;Inhibitory neurons: 74.8;Oligodendrocyte precursor cells: 87.9;Oligodendrocytes: 99.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029203 Approved Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA029203: AB_10602810" "unprognostic (1.49e-1)" "unprognostic (1.71e-2)" "unprognostic (5.21e-3)" "unprognostic (8.28e-2)" "unprognostic (8.25e-2)" "unprognostic (1.94e-3)" "unprognostic (1.67e-1)" "unprognostic (1.93e-2)" "unprognostic (1.15e-1)" "unprognostic (1.35e-1)" "unprognostic (2.15e-1)" "unprognostic (2.80e-1)" "prognostic favorable (3.64e-8)" "unprognostic (2.82e-2)" "unprognostic (6.60e-2)" "unprognostic (3.67e-3)" "unprognostic (1.56e-2)" 9.7 6.4 4.2 3.9 4.6 1.8 8.9 4.5 4.8 4.9 4.2 7.6 4.9 5.8 7.6 4.6 6.4 5.3 17.0 4.0 5.0 12.2 12.3 4.1 5.7 4.9 4.7 6.8 5.5 7.9 3.8 5.5 4.5 6.3 7.8 5.2 11.9 6.1 11.9 4.7 5.8 5.4 4.3 6.6 4.7 3.5 5.0 5.5 8.0 17.4 5.4 4.2 3.2 5.8 13.6 8.5 6.4 3.3 8.9 16.4 11.5 7.3 8.2 8.9 10.2 5.9 15.3 9.8 9.2 9.1 7.5 11.7 8.6 15.5 15.3 7.1 11.1 3.5 6.3 30.4 8.8 10.4 3.0 10.7 17.0 6.0 12.8 7.3 5.0 7.0 6.4 4.9 9.8 7.4 7.7 7.1 5.4 10.8 13.1 8.6 13.4 5.3 10.2 10.0 6.0 6.2 12.2 10.8 14.5 7.2 21.1 5.4 4.9 8.6 5.9 5.6 6.8 8.1 9.7 9.3 5.5 7.3 7.9 0.0 1.1 0.4 2.1 1.2 1.7 2.6 2.7 2.3 4.4 1.7 3.0 2.4 0.4 2.5 0.7 2.2 1.8 0.9 4.2 4.6 4.5 4.8 4.0 5.0 4.9 4.7 4.5 4.3 5.0 5.8 6.9 12.8 9.8 68.2 10.1 9.6 8.6 5.4 9.1 15.3 10.2 7.1 36.9 15.7 10.6 9.2 20.9 11.2 7.5 6.3 7.9 6.8 24.1 12.6 10.8 6.3 7.2 6.7 48.2 5.7 10.2 12.0 7.1 5.4 14.5 16.4 4.6 15.3 4.9 10.1 74.8 12.0 2.0 4.1 16.1 7.4 6.5 6.1 12.4 54.4 2.8 16.2 5.2 87.9 99.6 5.2 5.8 11.7 8.0 4.4 5.1 19.1 18.7 28.4 13.1 11.8 9.8 15.7 5.2 7.3 11.6 5.7 6.4 23.1 18.2 5.9 OCIAD1 "Asrij, FLJ20455, OCIA, TPA018" ENSG00000109180 "OCIA domain containing 1" Q9NX40 4 48805212-48861817 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044803 Approved Approved Mitochondria NA NA 21000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Mitochondria "HPA044803: AB_10961287" "unprognostic (8.18e-2)" "unprognostic (1.60e-2)" "unprognostic (4.82e-2)" "unprognostic (7.39e-2)" "unprognostic (1.69e-1)" "unprognostic (4.17e-2)" "unprognostic (2.53e-1)" "unprognostic (1.60e-1)" "unprognostic (4.10e-1)" "unprognostic (2.83e-3)" "unprognostic (1.34e-1)" "unprognostic (5.42e-2)" "unprognostic (1.47e-3)" "unprognostic (9.23e-2)" "unprognostic (2.86e-1)" "unprognostic (1.56e-1)" "unprognostic (1.16e-2)" 129.5 184.0 161.1 99.4 170.6 107.7 153.9 154.6 212.9 150.3 173.5 161.1 155.8 138.0 192.2 118.1 167.2 124.6 219.3 177.3 177.0 238.1 326.5 124.1 127.3 161.1 153.1 159.1 156.1 248.7 109.9 118.4 157.6 145.9 159.9 143.7 161.9 148.1 255.0 107.1 134.6 133.3 163.1 105.1 141.3 91.0 165.8 133.6 239.4 255.9 133.9 136.3 72.3 172.6 165.2 118.2 231.7 162.8 230.8 283.0 178.6 253.1 393.8 261.1 311.3 110.6 473.2 190.4 241.5 238.0 311.4 141.7 229.4 250.4 296.2 149.4 152.7 293.4 105.7 88.1 336.5 309.1 300.9 292.0 353.5 208.3 258.4 315.4 270.0 173.9 339.8 104.1 300.0 107.7 261.4 287.6 195.2 211.7 110.4 169.6 216.9 203.1 502.9 154.5 139.8 261.0 120.4 101.1 306.5 179.8 212.8 271.5 196.9 176.1 200.7 120.7 333.1 256.3 380.4 283.1 223.2 251.0 220.2 47.8 60.2 76.5 62.6 68.0 90.8 74.1 73.1 79.2 75.4 64.9 90.2 80.5 48.3 95.4 86.5 85.2 68.5 73.5 161.1 170.6 154.6 212.9 177.3 177.0 161.1 153.1 157.6 163.1 165.8 172.6 176.7 160.3 124.5 85.8 107.1 79.7 111.3 243.3 102.4 126.6 96.7 119.6 152.3 102.9 169.4 121.4 66.7 170.5 103.1 140.0 137.0 140.0 34.3 147.3 120.5 120.2 130.1 89.8 125.1 128.3 168.8 124.4 84.1 110.5 141.8 102.6 118.9 167.3 152.7 89.2 137.2 131.3 124.1 94.0 77.2 35.5 132.3 106.1 87.2 76.8 107.2 206.1 121.5 106.1 158.1 130.7 122.5 139.2 115.3 104.2 164.1 178.9 151.2 111.6 124.9 121.3 112.7 188.3 88.3 94.1 75.9 164.7 109.8 197.2 142.7 100.4 OCIAD2 MGC45416 ENSG00000145247 "OCIA domain containing 2" Q56VL3 4 48885019-48906937 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 155.4" "Cell type enhanced" "Detected in many" "Pancreatic endocrine cells: 1277.4;Proximal enterocytes: 702.0;Proximal tubular cells: 1384.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HBEC3-KT: 325.2;U-251 MG: 399.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040979, HPA041090" Enhanced Enhanced Mitochondria No No "Cluster 20: T-cells - T-cell receptor" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Mitochondria "HPA040979: AB_10795497, HPA041090: AB_10796236" "unprognostic (4.29e-1)" "unprognostic (2.69e-1)" "unprognostic (3.76e-2)" "prognostic favorable (7.37e-4)" "unprognostic (3.49e-2)" "unprognostic (1.66e-2)" "unprognostic (9.05e-2)" "unprognostic (1.23e-1)" "unprognostic (2.00e-1)" "prognostic favorable (6.56e-4)" "prognostic unfavorable (6.89e-4)" "unprognostic (1.38e-1)" "prognostic favorable (2.67e-5)" "unprognostic (1.10e-1)" "unprognostic (8.54e-2)" "unprognostic (8.24e-3)" "prognostic favorable (2.34e-4)" 9.2 20.4 14.1 22.1 13.1 16.3 23.4 10.3 15.3 19.8 14.1 54.7 122.3 20.7 46.9 25.8 22.4 32.4 14.3 17.8 15.6 155.4 129.5 19.0 34.6 13.1 13.2 8.7 26.9 44.4 33.6 8.6 11.7 23.8 49.9 26.9 40.2 29.2 4.4 20.0 88.4 15.0 11.6 12.6 85.0 6.3 13.7 53.6 37.4 3.9 40.3 28.1 12.0 12.7 208.9 108.5 1.6 0.0 0.0 0.0 2.7 53.3 23.9 28.4 26.9 0.0 249.4 35.7 230.1 30.5 248.0 65.5 29.7 325.2 29.1 83.8 22.6 0.1 78.6 0.1 25.6 101.7 0.3 14.7 150.8 0.1 61.1 81.4 115.5 140.2 0.1 17.6 30.3 78.3 172.2 70.2 102.5 234.2 145.2 38.5 0.1 59.4 288.7 135.0 230.3 69.5 75.4 25.5 5.4 0.8 26.2 25.2 195.6 0.2 215.1 1.2 399.5 49.5 59.6 113.3 163.0 0.3 0.4 208.4 3.5 69.1 101.6 1.5 136.9 168.0 191.0 147.3 18.1 156.7 247.2 165.0 11.2 156.0 1.3 122.4 338.7 137.7 14.1 13.1 10.3 15.3 17.8 15.6 13.1 13.2 11.7 11.6 13.7 12.7 135.9 28.9 70.6 2.0 102.5 109.0 146.6 401.4 81.4 17.6 152.7 190.6 39.2 194.5 224.2 176.6 29.2 46.2 66.3 359.7 217.2 510.5 1.4 197.5 22.9 103.3 306.4 38.9 10.1 570.2 11.4 14.9 157.5 190.8 36.8 75.3 31.1 193.9 44.3 1.7 11.6 301.3 341.8 6.4 27.0 2.5 5.0 21.7 65.8 5.6 15.9 49.9 82.4 2.5 1.8 1277.4 311.6 21.4 53.5 180.1 702.0 1384.9 171.4 77.6 0.0 3.7 41.8 2.6 3.2 105.2 131.4 15.3 129.8 52.1 188.6 239.2 OGDH "E1k, KGD1, OGDC-E1, OGDH2" ENSG00000105953 "Oxoglutarate dehydrogenase" Q02218 7 44606572-44709066 "Citric acid cycle related proteins, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 324.0;skeletal muscle: 363.6;tongue: 374.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 114.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019514, HPA020347" Supported Enhanced Mitochondria No No 130000 "Cluster 39: Non-specific - mRNA processing" "Cluster 8: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA019514: AB_1854772, HPA020347: AB_1854773" "unprognostic (1.96e-2)" "unprognostic (1.40e-1)" "unprognostic (4.39e-1)" "unprognostic (5.64e-3)" "unprognostic (3.02e-3)" "unprognostic (1.20e-1)" "unprognostic (3.45e-1)" "unprognostic (7.58e-2)" "unprognostic (1.74e-1)" "unprognostic (1.52e-2)" "unprognostic (3.38e-1)" "unprognostic (3.30e-2)" "prognostic favorable (2.22e-14)" "unprognostic (1.53e-1)" "unprognostic (1.62e-1)" "unprognostic (2.23e-2)" "unprognostic (5.88e-3)" 64.9 67.4 35.0 39.2 39.4 32.1 32.0 42.8 45.4 33.8 119.6 56.3 95.6 40.9 16.6 61.6 34.0 26.9 324.0 34.4 50.6 89.7 39.8 43.4 40.0 44.6 44.4 24.8 27.5 99.9 34.9 33.1 44.2 37.9 41.5 25.9 43.0 46.9 363.6 56.4 87.5 51.0 35.7 39.0 52.5 36.2 43.6 32.1 54.9 374.7 41.5 42.5 37.7 35.6 35.8 73.5 42.2 66.0 63.4 69.8 41.9 54.2 51.3 59.5 50.9 67.2 71.7 156.0 63.0 79.2 119.2 108.2 85.7 81.4 58.4 92.0 22.8 47.4 140.6 33.5 32.8 59.4 51.2 66.0 60.5 85.4 60.9 43.0 82.4 50.7 55.8 45.4 63.7 50.1 59.2 34.1 39.8 97.7 81.8 55.9 30.1 175.9 68.5 104.4 73.2 35.0 78.8 107.6 34.4 75.8 64.2 58.7 66.4 43.4 38.5 76.3 64.0 40.9 84.0 85.9 78.4 65.7 80.4 9.9 21.8 12.6 17.9 28.5 19.5 11.1 20.7 18.1 22.0 9.3 8.5 10.8 12.2 19.3 35.4 10.8 42.1 23.2 35.0 39.4 42.8 45.4 34.4 50.6 44.6 44.4 44.2 35.7 43.6 35.6 19.6 6.4 22.5 49.3 23.1 19.5 12.3 15.9 22.8 21.4 14.4 18.2 114.3 12.8 14.2 47.8 18.8 24.0 20.0 64.5 31.3 14.9 51.0 26.1 15.6 16.0 23.4 32.0 43.3 16.9 16.4 20.6 35.2 38.9 21.5 15.5 17.9 22.6 33.8 62.2 53.1 32.6 12.2 24.5 43.4 24.5 11.8 33.8 21.4 29.0 22.7 14.3 16.5 22.1 36.6 20.9 38.0 17.3 27.8 16.4 82.0 51.8 17.0 24.0 19.7 24.7 20.2 10.6 19.9 28.1 26.3 36.7 27.7 30.3 33.5 18.1 OSGEPL1 "OSGEPL, Qri7" ENSG00000128694 "O-sialoglycoprotein endopeptidase like 1" Q9H4B0 2 189746660-189763227 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Sertoli cells: 26.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030693 Uncertain Supported Mitochondria NA NA "Cluster 30: Non-specific - Translation" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 52: Non-specific - Transcription" Mitochondria "HPA030693: AB_10601978" "unprognostic (1.10e-1)" "unprognostic (8.72e-2)" "unprognostic (8.19e-2)" "unprognostic (6.70e-2)" "unprognostic (6.07e-2)" "unprognostic (6.38e-2)" "prognostic unfavorable (3.71e-4)" "unprognostic (4.18e-3)" "unprognostic (1.06e-3)" "prognostic favorable (3.19e-4)" "unprognostic (2.33e-1)" "unprognostic (1.80e-2)" "unprognostic (3.34e-2)" "unprognostic (2.68e-1)" "unprognostic (1.51e-2)" "unprognostic (6.39e-2)" "unprognostic (1.55e-3)" 3.9 8.2 3.6 3.5 5.0 1.9 7.2 6.1 5.0 4.5 3.0 3.5 3.3 5.7 5.6 4.0 5.2 3.2 8.9 3.4 4.0 8.4 7.9 3.9 6.5 4.3 4.5 8.7 3.1 4.7 2.7 4.0 4.5 4.1 3.9 9.8 4.7 3.7 12.3 6.1 3.5 5.0 4.3 5.4 3.1 6.4 3.9 5.6 5.2 11.0 6.3 3.6 3.0 6.1 7.1 3.8 16.7 12.7 12.9 7.1 9.8 10.8 7.5 14.9 15.9 4.5 7.1 4.7 11.7 4.5 8.2 10.1 15.0 12.7 16.9 12.3 11.5 15.3 9.0 5.9 6.7 8.8 7.6 7.8 10.6 11.5 5.5 10.2 11.3 11.8 5.6 7.2 9.8 3.9 6.8 9.9 8.1 9.5 17.4 7.5 13.4 8.1 9.7 3.8 10.1 11.2 7.3 12.8 23.9 20.6 10.1 9.9 4.7 9.6 8.5 14.3 6.8 7.3 6.6 7.4 12.7 11.0 10.7 0.5 2.7 2.3 7.5 2.7 10.6 7.7 7.7 8.6 3.8 9.8 11.3 10.5 0.4 7.6 2.4 6.6 6.6 3.1 3.6 5.0 6.1 5.0 3.4 4.0 4.3 4.5 4.5 4.3 3.9 6.1 3.6 6.4 3.6 6.8 8.4 1.9 2.8 5.9 5.2 8.9 4.0 4.8 8.6 8.6 2.8 0.0 12.5 10.6 7.3 0.4 7.9 3.0 1.4 3.5 5.5 4.1 0.0 5.2 6.6 2.3 7.3 4.5 1.5 2.3 3.8 6.8 3.6 2.9 4.4 10.1 10.0 1.1 2.0 2.4 1.7 0.8 11.1 4.1 1.8 5.6 1.8 12.0 13.4 10.1 17.0 2.0 1.0 8.2 1.9 1.1 1.7 10.2 6.0 11.8 26.3 5.8 8.4 9.6 13.7 4.4 2.0 2.2 6.0 11.8 2.2 1.0 OTC OTCase ENSG00000036473 "Ornithine carbamoyltransferase" P00480 X 38352586-38421446 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Arginine biosynthesis, Urea cycle" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 124 "intestine: 112.4;liver: 377.8" "Group enriched" "Detected in some" 5 "Hepatic stellate cells: 38.9;Hepatocytes: 99.6;Proximal enterocytes: 82.0;Undifferentiated cells: 25.3" "Cancer enriched" "Detected in some" 20 "liver cancer: 59.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA000243, HPA000570" Enhanced Supported Mitochondria NA NA 2200000 "Cluster 85: Liver - Metabolism" "Cluster 2: Hepatocytes - Metabolism" Mitochondria "HPA000243: AB_1079535, HPA000570: AB_1079534" "unprognostic (6.93e-2)" "unprognostic (2.48e-1)" "unprognostic (1.89e-3)" "unprognostic (4.38e-2)" "unprognostic (3.15e-1)" "unprognostic (1.33e-1)" "unprognostic (4.19e-2)" "unprognostic (7.70e-3)" "unprognostic (5.61e-2)" 1.2 0.0 0.2 0.5 0.3 0.0 0.2 0.3 0.4 0.4 0.1 5.0 112.4 0.7 0.0 0.4 0.5 0.4 0.3 0.2 0.3 0.1 377.8 0.9 0.1 0.3 0.3 0.1 1.7 0.0 0.0 0.0 0.4 0.0 2.5 0.1 0.1 0.1 0.0 0.0 87.4 0.5 0.3 0.0 1.9 0.4 0.3 0.0 0.3 0.0 0.0 0.1 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.3 0.4 0.2 0.3 0.3 0.3 0.4 0.3 0.3 0.4 0.3 0.0 0.0 1.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.8 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 7.4 0.1 0.0 1.7 1.2 0.0 0.5 0.2 0.0 0.2 0.0 0.0 0.0 0.0 38.9 99.6 0.0 0.0 0.5 8.3 0.0 3.5 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 10.9 0.0 0.0 0.0 82.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.0 0.0 0.0 0.0 0.3 0.0 25.3 0.0 OXA1L "MGC133129, OXA1" ENSG00000155463 "OXA1L mitochondrial inner membrane protein" Q15070 14 22766522-22773042 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003531 Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 32: Non-specific - Translation" Mitochondria "HPA003531: AB_1079539" "unprognostic (4.04e-3)" "unprognostic (2.41e-2)" "unprognostic (3.39e-1)" "unprognostic (2.24e-2)" "unprognostic (7.25e-2)" "unprognostic (1.42e-2)" "unprognostic (1.08e-2)" "unprognostic (1.06e-2)" "unprognostic (1.92e-1)" "unprognostic (1.01e-1)" "unprognostic (1.78e-1)" "unprognostic (1.78e-1)" "prognostic favorable (4.82e-4)" "unprognostic (8.35e-2)" "unprognostic (1.62e-1)" "unprognostic (4.37e-2)" "unprognostic (1.15e-3)" 77.7 90.7 27.6 40.8 28.5 71.9 67.6 31.4 28.8 59.4 47.1 72.9 66.3 55.0 48.1 76.6 55.8 49.6 147.2 27.5 29.6 70.8 108.6 54.8 70.0 31.3 29.1 71.2 98.0 105.3 27.5 38.0 31.1 45.0 57.7 41.9 64.2 44.8 234.9 69.3 58.9 46.1 29.1 62.3 83.9 25.0 31.6 63.6 54.9 272.5 75.5 61.3 60.4 31.1 89.3 121.3 48.8 82.1 146.7 217.4 94.4 64.0 138.1 94.3 107.9 91.1 96.4 167.0 86.4 75.0 73.0 121.0 103.0 126.3 90.0 67.6 65.4 79.1 73.2 329.7 165.5 150.9 88.4 211.0 137.6 75.4 114.9 114.7 273.3 93.8 62.2 124.0 103.4 130.0 91.8 51.3 53.2 118.5 150.0 92.9 87.2 128.3 117.9 103.4 35.1 67.0 94.6 205.7 129.7 58.4 89.2 122.7 86.2 52.7 62.2 98.5 75.4 94.0 84.7 78.1 41.6 83.6 60.0 11.9 68.1 18.5 29.5 71.6 36.0 51.0 42.5 37.4 95.1 54.4 47.4 35.6 15.1 41.7 58.5 26.9 55.8 53.7 27.6 28.5 31.4 28.8 27.5 29.6 31.3 29.1 31.1 29.1 31.6 31.1 30.6 48.1 44.0 7.8 83.7 69.5 61.1 89.0 92.8 31.0 52.1 46.5 118.0 72.9 62.1 29.5 10.4 72.8 32.5 48.9 74.3 85.2 10.2 20.4 40.3 58.6 40.7 64.3 6.8 161.3 113.0 47.6 66.8 23.1 80.4 56.5 64.2 102.9 143.4 18.5 7.5 75.3 38.7 148.1 76.8 13.3 57.2 85.6 51.6 3.7 133.4 22.9 74.2 4.5 8.0 86.3 69.7 36.9 84.2 45.6 101.4 116.0 42.6 38.3 39.5 39.4 43.0 31.8 28.4 112.9 67.3 57.2 57.9 70.6 112.1 74.9 OXCT1 "OXCT, SCOT" ENSG00000083720 "3-oxoacid CoA-transferase 1" P55809 5 41730065-41870425 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 245.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 243.7;Distal tubular cells: 187.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HeLa: 238.7;SiHa: 319.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012047, HPA061425" Enhanced Enhanced Mitochondria "Intracellular and membrane" NA NA 440000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA012047: AB_1854857, HPA061425: AB_2684515" "unprognostic (4.26e-2)" "unprognostic (2.10e-2)" "unprognostic (2.89e-2)" "unprognostic (1.51e-1)" "unprognostic (5.51e-2)" "unprognostic (1.82e-2)" "prognostic unfavorable (1.03e-4)" "unprognostic (7.42e-3)" "unprognostic (1.74e-3)" "unprognostic (1.67e-1)" "unprognostic (2.80e-2)" "unprognostic (3.62e-1)" "prognostic favorable (1.86e-8)" "unprognostic (2.66e-2)" "unprognostic (9.99e-2)" "unprognostic (5.86e-3)" "unprognostic (2.28e-3)" 52.7 15.8 30.4 16.6 34.9 13.3 18.5 23.9 32.7 13.5 15.9 19.2 8.3 14.9 17.6 26.8 12.4 15.2 245.9 36.2 27.1 53.1 1.3 8.0 21.7 19.5 21.4 13.8 5.3 48.6 14.7 5.0 20.0 25.5 21.1 23.6 18.9 29.8 28.5 23.1 12.8 36.6 19.3 11.0 34.2 13.2 25.7 76.8 27.3 42.6 25.9 15.1 13.8 24.5 35.3 1.6 27.9 33.6 84.7 45.0 0.1 62.1 38.9 50.3 30.4 5.7 23.5 91.2 15.0 47.5 25.8 20.5 77.5 55.9 58.5 78.5 9.1 63.9 238.7 11.9 36.8 125.8 20.9 42.7 15.3 49.3 82.2 24.6 46.4 81.6 13.3 114.0 58.1 4.5 105.5 6.1 6.4 0.0 24.5 82.8 78.9 68.7 41.7 2.9 27.9 28.8 319.5 0.3 38.3 2.5 0.4 27.4 28.3 39.7 51.9 68.6 50.6 18.6 16.5 3.6 59.9 90.9 30.9 1.4 1.4 4.7 11.6 1.5 13.8 10.0 11.5 12.7 6.3 7.5 13.6 10.9 0.4 11.3 2.5 2.4 21.5 6.6 30.4 34.9 23.9 32.7 36.2 27.1 19.5 21.4 20.0 19.3 25.7 24.5 8.4 6.4 9.2 37.5 19.2 14.8 11.7 12.4 17.6 14.1 18.8 14.2 243.7 7.2 14.3 11.0 2.1 7.0 18.3 5.0 187.9 5.4 19.1 11.7 18.8 9.8 13.2 23.1 71.5 0.7 11.9 21.3 20.4 31.2 9.5 8.7 6.8 0.3 38.2 13.5 84.2 18.6 12.2 1.3 7.0 8.6 6.2 5.2 16.0 26.2 4.4 11.8 10.3 66.4 46.8 4.8 5.3 7.5 31.3 12.1 2.9 27.4 5.6 21.6 13.1 9.7 24.6 35.6 19.7 27.6 21.6 6.8 26.6 8.6 18.1 9.0 PACS2 "KIAA0602, PACS1L" ENSG00000179364 "Phosphofurin acidic cluster sorting protein 2" Q86VP3 14 105300563-105398147 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Apoptosis, Host-virus interaction" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 136.6;skeletal muscle: 98.5" "Cell type enhanced" "Detected in all" "Horizontal cells: 97.6;Oligodendrocytes: 169.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077892 Approved Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA077892: AB_2686865" "unprognostic (4.31e-2)" "unprognostic (2.61e-1)" "unprognostic (4.53e-2)" "unprognostic (1.24e-1)" "unprognostic (3.09e-2)" "unprognostic (4.08e-2)" "prognostic unfavorable (3.11e-5)" "unprognostic (1.18e-2)" "unprognostic (1.37e-1)" "unprognostic (1.90e-1)" "prognostic favorable (2.95e-4)" "unprognostic (1.49e-1)" "prognostic favorable (1.56e-4)" "unprognostic (2.08e-1)" "unprognostic (3.80e-1)" "unprognostic (2.58e-1)" "unprognostic (1.30e-1)" 22.4 16.1 48.4 10.6 101.5 9.0 18.7 104.4 61.3 18.1 4.7 24.6 10.9 21.0 5.4 11.2 19.0 11.2 23.8 43.2 58.0 12.4 6.9 16.1 8.5 136.6 110.6 20.0 28.8 11.7 21.6 8.8 119.6 15.0 6.6 12.2 16.3 11.5 98.5 12.6 14.2 10.0 80.8 16.0 17.4 19.8 106.1 9.4 14.1 46.1 5.5 19.3 14.1 126.8 17.5 23.8 21.9 20.7 21.5 20.6 25.9 13.0 15.0 11.0 9.6 10.4 32.5 19.0 21.5 20.0 14.1 19.7 13.5 18.7 7.9 23.7 11.0 8.7 10.0 15.6 28.1 7.1 15.0 24.1 17.5 7.7 17.7 13.9 20.1 18.9 5.4 17.2 9.7 54.9 12.1 9.5 8.5 22.1 19.4 26.5 13.3 12.1 9.3 39.7 49.0 25.8 12.4 11.1 19.4 13.7 28.1 13.2 30.8 16.2 7.2 25.6 13.1 22.3 15.6 7.2 24.6 12.8 16.1 0.0 0.6 0.1 0.3 1.1 0.6 0.0 0.3 0.4 1.1 0.2 0.1 0.4 0.1 1.0 1.9 2.3 0.8 0.4 48.4 101.5 104.4 61.3 43.2 58.0 136.6 110.6 119.6 80.8 106.1 126.8 28.3 9.6 14.7 41.1 3.3 9.1 7.5 7.1 8.0 30.5 15.1 14.4 21.4 8.6 12.6 5.5 12.5 4.3 15.1 21.5 13.7 13.9 77.1 13.8 15.7 21.1 13.1 4.2 29.7 23.0 3.2 15.5 20.4 18.3 1.3 28.8 19.2 10.8 17.6 97.6 41.0 14.6 8.2 15.7 23.0 78.7 17.4 17.1 26.6 30.9 8.4 17.0 7.2 23.1 169.3 14.2 12.6 16.6 7.1 9.0 19.3 12.3 7.7 23.4 6.6 20.6 14.2 18.3 14.6 8.1 8.4 3.4 8.0 30.6 19.5 8.0 PAGE5 "CT16.1, CT16.2, PAGE-5" ENSG00000158639 "PAGE family member 5" Q96GU1 X 55220346-55224108 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 25 "testis: 26.5" "Group enriched" "Detected in some" 7 "Spermatocytes: 131.0;Spermatogonia: 158.8" "Group enriched" "Detected in many" 6 "liver cancer: 5.4;melanoma: 11.8;testis cancer: 6.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 1.9" "Lineage enriched" "Detected in single" 13 "T-cells: 1.9" "Group enriched" "Detected in some" 170 "Karpas-707: 437.8;U-266/84: 992.7" "HPA052619, HPA055869" Supported Approved Mitochondria NA NA "Cluster 13: T-cells - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Mitochondria "HPA052619: AB_2681887, HPA055869: " "unprognostic (4.03e-1)" "unprognostic (4.51e-2)" "unprognostic (7.86e-4)" "unprognostic (1.39e-2)" "unprognostic (7.21e-2)" "unprognostic (1.06e-4)" "unprognostic (2.29e-1)" "unprognostic (1.94e-1)" "unprognostic (3.44e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.1 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.3 26.5 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.7 0.1 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 437.8 0.0 0.0 1.2 0.0 0.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.4 0.0 0.0 0.5 1.3 1.6 4.2 992.7 0.5 0.1 0.0 0.7 0.0 0.0 0.0 0.3 0.0 1.9 0.1 1.6 0.7 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.1 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 19.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.0 0.3 11.9 2.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.5 0.1 0.0 6.6 0.0 0.1 131.0 158.8 0.0 0.1 0.0 1.4 0.0 0.0 0.1 PAPSS2 ATPSK2 ENSG00000198682 "3'-phosphoadenosine 5'-phosphosulfate synthase 2" O95340 10 87659613-87747705 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Multifunctional enzyme, Nucleotidyltransferase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 135.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 240.4;Distal enterocytes: 202.4;Hepatocytes: 111.5;Proximal enterocytes: 181.3;Theca cells: 96.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 4.0;myeloid DC: 2.1;non-classical monocyte: 7.7" "Group enriched" "Detected in many" 7 "dendritic cells: 2.1;monocytes: 7.7" "Cell line enhanced" "Detected in many" "BJ: 189.8;fHDF/TERT166: 473.2;HHSteC: 196.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071224, HPA075267" Enhanced Approved Mitochondria No No 16000 "Cluster 7: Monocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" Mitochondria "HPA071224: AB_2686366, HPA075267: " "unprognostic (3.98e-3)" "unprognostic (7.06e-2)" "unprognostic (4.95e-3)" "unprognostic (1.02e-1)" "unprognostic (2.67e-1)" "unprognostic (1.61e-2)" "unprognostic (4.96e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.33e-6)" "unprognostic (3.50e-2)" "prognostic favorable (6.58e-4)" "unprognostic (1.14e-1)" "unprognostic (4.90e-2)" "unprognostic (6.72e-3)" "unprognostic (1.73e-1)" "prognostic unfavorable (3.21e-5)" "unprognostic (3.46e-3)" 33.3 135.2 6.3 26.6 7.0 2.0 20.9 6.2 9.5 17.8 6.2 79.9 29.5 8.5 3.1 10.2 12.4 20.7 11.6 5.8 6.2 23.8 77.0 70.4 11.0 6.9 6.6 27.5 26.1 2.1 3.0 58.5 7.5 6.7 64.3 2.3 16.4 3.4 4.7 3.5 61.8 16.7 6.8 8.5 9.2 11.7 8.0 3.0 21.3 8.7 14.8 16.6 11.5 7.2 19.9 20.0 6.4 0.3 129.4 164.8 0.3 189.8 157.7 110.4 79.9 1.0 4.1 0.1 9.8 473.2 3.5 8.5 13.9 13.3 125.2 0.2 10.0 8.8 13.4 0.1 196.5 0.2 3.8 58.7 0.3 63.7 5.2 135.6 94.2 1.4 0.0 89.4 79.2 74.1 0.1 0.7 7.4 4.8 24.1 0.4 0.1 0.4 117.5 8.7 0.9 1.6 92.5 3.3 1.1 12.6 13.5 5.3 120.0 38.2 22.5 131.5 13.9 0.3 1.0 0.3 18.3 0.2 0.2 0.0 1.1 0.0 0.0 4.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.6 0.0 7.7 0.0 0.0 0.8 6.3 7.0 6.2 9.5 5.8 6.2 6.9 6.6 7.5 6.8 8.0 7.2 49.5 240.4 38.2 3.6 2.6 2.3 0.9 18.0 1.8 0.2 11.5 4.7 4.4 8.6 13.8 9.2 0.0 0.5 0.8 202.4 13.7 6.4 1.2 2.6 18.7 23.2 12.6 5.2 22.2 30.2 0.8 36.1 15.3 11.6 0.0 20.3 36.0 111.5 11.5 0.0 27.6 26.5 4.1 29.8 50.7 0.8 17.4 51.0 1.8 30.0 5.2 1.3 0.0 21.6 1.0 19.4 46.1 5.3 3.1 2.1 181.3 9.8 3.4 0.0 13.1 1.0 20.4 1.2 0.7 1.1 1.3 1.4 1.7 96.4 74.3 1.1 PARL "PRO2207, PSARL, PSARL1, RHBDS1" ENSG00000175193 "Presenilin associated rhomboid like" Q9H300 3 183829271-183884933 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA019545 Approved Approved Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA019545: AB_1855796" "unprognostic (2.10e-1)" "unprognostic (1.53e-3)" "unprognostic (5.88e-2)" "unprognostic (1.17e-2)" "unprognostic (5.76e-2)" "unprognostic (9.55e-2)" "unprognostic (3.17e-3)" "unprognostic (8.97e-2)" "unprognostic (1.81e-1)" "unprognostic (3.62e-3)" "unprognostic (1.52e-1)" "unprognostic (2.13e-2)" "unprognostic (4.28e-2)" "unprognostic (5.49e-2)" "unprognostic (2.58e-1)" "unprognostic (1.73e-1)" "prognostic favorable (9.11e-5)" 38.4 35.8 46.5 26.6 48.2 33.8 40.3 47.4 66.2 33.8 50.7 47.7 29.2 31.9 57.7 36.7 30.2 19.7 54.1 46.6 48.2 39.6 45.0 28.4 32.0 47.7 48.7 31.7 49.9 39.7 32.0 25.5 47.4 37.1 41.9 32.7 40.5 30.3 54.9 37.1 34.7 29.7 47.2 36.2 42.6 26.7 47.6 34.5 31.4 51.6 33.8 38.9 31.5 48.4 115.1 55.6 39.7 33.0 38.8 42.1 80.2 39.2 59.4 80.5 65.0 172.0 59.0 47.8 90.0 56.7 73.5 49.2 64.1 68.0 90.0 71.6 76.1 73.9 35.5 96.9 57.3 73.9 61.6 60.0 85.4 58.0 70.7 38.5 59.0 82.4 42.6 45.0 69.2 131.0 148.3 194.3 105.5 100.6 53.3 64.7 72.8 92.0 79.0 97.6 37.9 52.0 47.6 162.9 107.8 48.1 159.2 143.5 31.8 29.3 63.0 60.9 108.2 89.2 65.7 116.0 56.6 75.1 35.5 97.5 143.1 133.4 51.3 107.8 60.9 62.4 57.3 59.9 132.4 59.1 68.7 54.2 41.3 67.1 83.3 79.7 73.7 116.1 46.5 48.2 47.4 66.2 46.6 48.2 47.7 48.7 47.4 47.2 47.6 48.4 30.3 22.4 19.7 17.9 37.6 30.3 54.9 93.5 26.7 35.9 31.8 31.5 41.2 35.8 44.5 31.3 31.3 58.9 38.4 24.4 117.4 63.9 24.0 15.2 18.3 30.2 33.7 23.3 23.4 84.7 49.0 35.1 28.1 13.7 69.8 33.1 33.2 30.4 77.7 33.7 24.1 42.0 77.3 56.2 55.7 9.7 28.9 57.5 42.7 33.7 79.3 55.9 50.4 17.1 28.0 60.3 35.1 27.1 42.3 55.4 47.3 86.0 30.5 51.1 6.6 44.8 96.6 47.8 47.4 40.2 30.0 42.1 40.9 49.0 49.2 58.8 PARP15 "ARTD7, FLJ40597, pART7" ENSG00000173200 "Poly(ADP-ribose) polymerase family member 15" Q460N3 3 122577628-122639047 "Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 23.1;intestine: 42.1;lymphoid tissue: 67.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 19.2;B-cells: 88.4;dendritic cells: 38.6;granulocytes: 19.6;NK-cells: 21.6;Plasma cells: 18.6;T-cells: 31.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 7.6;JURKAT: 5.1;REH: 3.5;THP-1: 3.7;TIME: 8.9" "Low region specificity" "Detected in single" HPA035757 Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 57: B-cells - Immune response" Mitochondria "HPA035757: AB_10669656" "unprognostic (8.19e-3)" "unprognostic (2.88e-3)" "unprognostic (1.12e-1)" "unprognostic (1.18e-3)" "unprognostic (1.22e-1)" "unprognostic (9.01e-5)" "unprognostic (4.79e-2)" "unprognostic (1.83e-2)" "unprognostic (3.91e-2)" "unprognostic (5.40e-2)" "unprognostic (1.61e-1)" "unprognostic (9.63e-2)" "unprognostic (9.24e-7)" "unprognostic (9.03e-2)" "unprognostic (2.07e-2)" "unprognostic (1.52e-1)" "unprognostic (1.22e-2)" 3.7 1.2 3.1 25.7 2.7 23.1 1.8 4.2 3.8 1.7 1.2 3.8 2.6 1.9 1.3 2.0 2.0 4.4 1.7 2.1 1.2 1.7 3.2 9.0 44.4 1.8 2.3 0.7 0.8 0.2 0.7 2.5 1.7 1.8 4.8 2.2 2.2 1.1 6.0 1.2 42.1 1.9 0.7 67.2 4.1 2.5 2.0 8.3 3.0 1.9 50.3 4.5 1.6 3.6 0.3 0.2 0.3 0.3 0.1 0.2 0.3 0.2 0.1 0.0 0.0 0.2 0.7 0.3 0.4 0.1 0.2 0.3 0.0 0.0 0.0 0.7 0.1 7.6 0.5 0.3 0.1 0.5 0.3 1.5 0.1 0.3 0.1 0.2 1.7 5.1 0.2 1.3 0.0 0.3 2.3 0.4 0.4 0.1 0.1 3.5 0.2 0.3 0.0 0.6 0.5 0.3 0.1 0.1 0.1 0.3 0.5 3.7 8.9 0.2 0.6 0.3 0.2 0.6 0.4 1.6 0.4 0.2 0.1 1.8 0.2 0.1 7.2 0.3 5.8 9.4 4.4 5.4 0.8 9.3 3.8 4.8 0.5 3.9 0.7 1.0 4.2 2.2 3.1 2.7 4.2 3.8 2.1 1.2 1.8 2.3 1.7 0.7 2.0 3.6 0.8 19.2 15.9 0.0 88.4 0.5 0.0 0.0 0.0 0.0 0.6 0.6 0.7 0.0 2.1 0.0 0.0 0.1 38.6 0.1 0.0 0.0 0.2 0.3 0.1 1.2 0.0 7.4 0.1 0.0 0.1 2.7 2.6 0.3 19.6 0.0 2.2 0.6 8.3 0.0 0.2 0.0 0.0 5.1 1.4 0.2 0.0 6.4 1.8 6.5 4.7 0.0 21.6 0.0 0.1 0.1 0.0 0.0 18.6 0.0 0.0 0.1 10.5 0.0 0.0 0.7 0.4 0.1 1.6 0.4 0.0 0.3 31.1 0.0 0.0 0.0 PC PCB ENSG00000173599 "Pyruvate carboxylase" P11498 11 66848417-66958386 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Gluconeogenesis, Lipid biosynthesis, Lipid metabolism" "Ligase, Multifunctional enzyme" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 148.0" "Cell type enhanced" "Detected in many" "Hepatocytes: 201.9;Late spermatids: 53.2" "Cancer enhanced" "Detected in all" "liver cancer: 37.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HeLa: 57.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033742, HPA043922, HPA058765" Enhanced Enhanced Mitochondria Yes No 200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 15: Hepatocytes - Hemostasis" Mitochondria "CAB033742: AB_2283532, HPA043922: AB_2678732, HPA058765: AB_2683812" "unprognostic (2.10e-1)" "unprognostic (1.51e-1)" "unprognostic (1.36e-2)" "unprognostic (8.24e-3)" "unprognostic (3.67e-1)" "unprognostic (3.18e-2)" "unprognostic (2.97e-1)" "unprognostic (3.00e-1)" "unprognostic (3.63e-1)" "prognostic unfavorable (7.86e-5)" "unprognostic (1.54e-1)" "unprognostic (1.17e-1)" "prognostic favorable (8.22e-5)" "unprognostic (8.58e-3)" "unprognostic (5.67e-2)" "unprognostic (9.15e-3)" "unprognostic (1.05e-1)" 60.9 23.7 35.7 2.9 35.5 3.5 28.4 36.6 35.8 3.7 17.5 4.7 6.5 3.8 1.8 9.3 3.2 2.8 4.3 32.4 41.0 23.3 148.0 2.6 1.3 43.4 40.1 5.1 4.9 18.2 8.6 4.4 37.6 7.2 2.8 2.4 35.3 9.3 12.1 4.7 7.7 1.4 37.8 1.5 9.1 10.7 49.0 2.0 4.6 6.6 2.0 2.9 4.4 37.0 6.1 19.3 6.5 17.2 25.4 8.9 6.6 3.4 15.5 6.9 7.5 8.8 6.0 0.0 7.4 6.0 9.6 6.8 7.7 39.5 1.5 2.8 11.0 10.3 57.4 41.2 21.0 0.1 10.8 40.2 10.1 5.8 12.4 4.4 5.7 14.3 17.4 0.0 2.1 44.6 9.2 4.6 12.0 15.1 16.2 8.3 13.0 3.2 5.7 1.9 15.2 21.0 33.6 18.0 15.5 4.8 14.6 2.7 6.3 7.8 6.6 8.8 4.7 3.5 4.8 0.1 7.7 5.7 6.7 0.0 1.3 0.0 0.5 0.3 0.5 0.0 0.1 0.5 0.9 0.2 0.9 0.5 0.1 0.1 0.1 0.3 0.5 0.7 35.7 35.5 36.6 35.8 32.4 41.0 43.4 40.1 37.6 37.8 49.0 37.0 0.9 0.0 3.0 26.4 1.4 1.3 1.6 9.1 2.8 5.6 4.8 5.8 4.4 11.5 3.0 3.7 2.1 17.4 0.6 27.6 1.9 3.1 18.4 2.3 7.1 1.5 9.0 28.0 18.5 1.8 4.2 3.2 5.6 3.0 8.9 16.0 4.6 201.9 12.3 0.0 18.6 5.0 0.0 7.0 1.8 53.2 0.6 1.8 5.4 7.5 18.9 9.4 2.1 10.1 16.7 2.3 8.5 4.1 0.1 3.1 23.6 39.0 1.5 4.8 0.0 2.2 2.2 11.2 4.7 4.1 0.6 25.4 1.2 6.0 6.4 1.3 PCCA ENSG00000175198 "Propionyl-CoA carboxylase subunit alpha" P05165 13 100089015-100530437 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 218.2" "Cell type enhanced" "Detected in all" "Astrocytes: 152.8;Excitatory neurons: 152.8;Inhibitory neurons: 166.5;Microglial cells: 217.4;Oligodendrocyte precursor cells: 200.6;Oligodendrocytes: 182.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 167.0;SCLC-21H: 91.1;U-937: 131.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041716, HPA047792" Enhanced Supported Mitochondria NA NA 290000 "Cluster 27: Non-specific - Gene expression" "Cluster 68: Epididymis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 68: Oligodendrocytes - Mixed function" Mitochondria "HPA041716: AB_2677635, HPA047792: AB_2680156" "unprognostic (1.18e-1)" "unprognostic (2.13e-1)" "unprognostic (1.97e-2)" "unprognostic (4.71e-2)" "unprognostic (1.11e-2)" "unprognostic (1.71e-2)" "unprognostic (1.55e-1)" "unprognostic (5.90e-3)" "unprognostic (2.41e-1)" "unprognostic (1.55e-1)" "unprognostic (6.14e-2)" "unprognostic (1.42e-1)" "prognostic favorable (0.00e+0)" "unprognostic (7.08e-2)" "unprognostic (1.12e-1)" "unprognostic (1.18e-1)" "unprognostic (9.32e-2)" 35.4 56.3 29.0 12.4 29.8 6.2 25.8 55.5 34.6 22.3 44.4 37.5 13.2 14.9 218.2 19.4 17.4 11.6 35.4 28.6 26.3 111.7 104.3 12.0 8.0 28.9 27.4 19.9 27.6 25.7 12.3 21.3 31.1 25.9 27.6 25.2 26.9 16.9 17.6 18.6 18.0 13.7 30.3 17.2 40.9 9.2 33.9 11.4 20.4 27.2 6.4 21.3 17.5 38.7 10.6 18.5 29.8 9.9 27.9 24.2 16.6 10.2 15.4 9.5 9.0 23.0 13.9 0.8 15.2 10.1 12.0 11.8 9.1 14.1 15.6 17.5 10.1 24.6 12.7 49.7 15.4 1.2 11.3 22.4 15.2 8.8 14.6 23.0 19.6 13.0 9.8 13.4 17.1 11.6 2.6 54.8 18.6 37.2 8.1 21.4 12.9 17.3 167.0 20.5 91.1 10.9 7.0 38.4 17.9 31.9 27.9 43.1 14.3 9.6 8.0 6.7 7.3 13.1 12.9 0.4 18.4 131.6 6.9 1.6 9.1 1.7 4.5 11.2 5.9 3.6 2.8 4.2 13.5 2.3 3.9 4.9 1.1 8.7 12.3 1.1 6.5 5.2 29.0 29.8 55.5 34.6 28.6 26.3 28.9 27.4 31.1 30.3 33.9 38.7 11.3 3.2 8.7 152.8 6.6 1.9 29.1 12.7 8.6 15.5 13.5 8.8 10.5 52.9 14.8 20.2 29.2 25.7 4.3 20.7 99.7 19.7 17.6 76.5 22.4 12.0 3.6 3.4 152.8 8.4 6.9 12.9 12.2 72.9 14.0 20.7 12.1 48.8 11.8 28.6 166.5 12.4 12.2 14.2 2.2 12.0 8.7 8.2 5.4 217.4 6.0 11.5 10.3 200.6 182.5 5.8 17.5 13.5 9.4 11.2 13.2 86.9 13.2 31.7 13.1 12.3 10.1 7.2 6.2 10.6 3.8 30.2 6.4 17.6 27.6 19.2 PCDHB15 PCDH-BETA15 ENSG00000113248 "Protocadherin beta 15" Q9Y5E8 5 141245395-141249365 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 4.3;Bipolar cells: 4.4;Early spermatids: 7.5;Endometrial stromal cells: 4.4;Fibroblasts: 3.7;Horizontal cells: 5.0;Skeletal myocytes: 4.2;Smooth muscle cells: 4.1;Spermatocytes: 4.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 6.2;LHCN-M2: 4.9;WM-115: 4.9" "Low region specificity" "Detected in all" "HPA007172, CAB026471, HPA074676" Uncertain Approved Mitochondria NA NA 250000 "Cluster 21: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "CAB026471: , HPA007172: AB_1079576, HPA074676: AB_2732263" "unprognostic (1.39e-1)" "unprognostic (1.58e-1)" "unprognostic (7.37e-3)" "unprognostic (1.75e-1)" "unprognostic (2.06e-2)" "unprognostic (6.19e-2)" "unprognostic (1.60e-1)" "unprognostic (4.12e-2)" "unprognostic (1.87e-2)" "unprognostic (7.58e-2)" "unprognostic (7.01e-2)" "unprognostic (6.00e-2)" "unprognostic (9.37e-2)" "unprognostic (1.08e-2)" "unprognostic (2.02e-1)" "unprognostic (1.08e-1)" "unprognostic (1.59e-1)" 3.8 1.4 1.9 2.5 2.1 0.0 2.6 4.2 2.4 6.4 0.0 3.8 0.5 6.8 2.5 1.4 5.0 2.1 4.4 1.8 1.6 2.1 1.1 3.7 0.7 3.0 2.5 7.4 3.3 0.8 3.5 1.5 2.0 2.4 0.9 2.0 1.7 2.0 1.3 1.3 1.8 4.1 2.5 2.5 2.1 5.4 2.3 0.3 2.7 1.4 0.5 3.6 3.2 2.4 0.2 0.0 6.2 0.7 1.5 1.6 0.1 0.4 1.2 0.1 0.3 0.0 0.3 0.0 1.2 0.9 1.6 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.9 0.2 0.2 0.0 0.0 0.7 1.3 0.0 0.2 1.6 0.3 0.0 0.0 1.0 4.9 0.0 0.0 0.1 1.5 0.0 0.0 0.2 0.7 0.0 0.4 0.1 0.3 0.8 0.3 0.3 1.6 0.8 0.3 0.0 0.0 0.6 0.6 2.2 0.0 0.1 0.8 0.0 0.8 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.1 4.2 2.4 1.8 1.6 3.0 2.5 2.0 2.5 2.3 2.4 4.3 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 4.4 0.2 0.3 1.4 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.2 7.5 0.2 4.4 2.4 0.0 0.0 0.0 1.5 0.0 3.7 0.5 0.2 0.0 0.6 1.4 0.0 0.1 5.0 0.0 0.0 0.0 0.0 0.0 2.3 0.6 0.0 1.8 0.0 0.0 1.3 0.0 0.0 0.0 0.9 0.1 3.4 0.0 0.1 0.0 0.7 0.1 0.8 0.0 4.2 4.1 4.8 0.7 0.2 0.6 0.0 0.1 0.5 0.1 0.3 PCK2 "PEPCK, PEPCK2" ENSG00000100889 "Phosphoenolpyruvate carboxykinase 2, mitochondrial" Q16822 14 24094053-24110598 "Citric acid cycle related proteins, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Gluconeogenesis "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "intestine: 196.1;kidney: 99.1;liver: 374.1" "Group enriched" "Detected in many" 4 "Hepatocytes: 309.3;Proximal enterocytes: 752.6;Proximal tubular cells: 237.1" "Cancer enhanced" "Detected in all" "liver cancer: 91.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 104.7;hTCEpi: 104.7;SK-MEL-30: 103.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB018734, HPA051162, HPA053502" Enhanced Enhanced Mitochondria NA NA 3500000 "Cluster 51: Monocytes - Innate immune response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "CAB018734: AB_2160168, HPA051162: AB_2681368, HPA053502: AB_2682171" "unprognostic (3.38e-2)" "unprognostic (1.13e-1)" "unprognostic (1.50e-2)" "unprognostic (4.07e-1)" "unprognostic (3.11e-1)" "unprognostic (2.10e-1)" "prognostic favorable (2.81e-4)" "unprognostic (3.91e-2)" "unprognostic (1.04e-1)" "unprognostic (2.18e-2)" "unprognostic (1.26e-1)" "unprognostic (3.67e-2)" "unprognostic (1.33e-2)" "unprognostic (2.81e-1)" "unprognostic (3.71e-1)" "unprognostic (2.82e-2)" "unprognostic (1.17e-1)" 25.5 10.7 3.2 8.0 3.9 4.5 21.1 3.8 3.3 6.8 3.4 44.8 196.1 5.8 3.1 20.0 5.9 4.5 5.8 3.1 3.9 99.1 374.1 16.5 8.7 4.6 4.2 3.0 34.8 17.4 8.0 2.8 4.1 9.1 19.2 2.7 18.6 7.1 2.6 12.6 136.3 3.8 4.0 21.7 16.0 19.7 3.9 3.7 18.9 1.2 7.5 10.8 10.0 4.3 17.6 9.8 2.7 18.1 11.0 10.5 46.0 21.5 25.6 17.4 28.4 16.1 19.9 44.6 2.6 33.4 5.6 25.4 18.0 28.1 13.8 22.8 0.8 8.0 5.0 84.2 104.7 15.8 33.4 12.9 104.7 10.6 26.5 5.0 14.0 50.6 23.4 79.3 6.4 74.6 4.0 7.6 3.1 39.4 13.0 8.7 10.5 26.0 5.3 26.7 11.3 18.2 16.5 21.2 103.9 2.6 28.5 24.1 2.7 3.8 19.7 5.6 6.0 53.2 18.6 11.0 10.6 24.5 9.6 0.3 11.6 3.5 4.0 21.6 4.1 11.4 4.5 4.5 15.3 7.3 2.7 2.5 1.3 2.2 22.0 2.5 9.1 6.1 3.2 3.9 3.8 3.3 3.1 3.9 4.6 4.2 4.1 4.0 3.9 4.3 4.8 12.8 28.5 1.3 17.9 3.3 10.2 12.3 5.7 4.7 8.6 5.2 1.8 18.6 8.0 18.4 0.0 4.7 4.3 91.2 35.2 18.9 60.1 1.6 5.2 5.6 9.1 24.4 0.5 76.3 14.3 7.4 16.8 4.5 1.3 1.6 13.2 309.3 63.8 0.0 0.9 60.8 18.3 25.8 5.7 30.8 3.4 16.4 7.2 1.0 22.9 5.8 7.2 0.0 0.1 29.0 87.8 3.0 13.3 7.6 752.6 237.1 4.8 5.5 0.0 3.4 18.7 19.8 1.0 9.1 4.8 3.0 7.6 6.8 72.0 15.0 PDCD2L MGC13096 ENSG00000126249 "Programmed cell death 2 like" Q9BRP1 19 34404399-34426168 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 24.7" "Cell type enhanced" "Detected in many" "Spermatocytes: 35.7;Spermatogonia: 42.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052181 Approved Approved Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 80: Striated muscle - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA052181: AB_2681751" "unprognostic (5.39e-2)" "unprognostic (3.48e-1)" "unprognostic (1.51e-1)" "unprognostic (6.99e-2)" "unprognostic (1.07e-1)" "unprognostic (3.22e-1)" "prognostic unfavorable (5.81e-4)" "unprognostic (1.82e-1)" "unprognostic (1.49e-1)" "unprognostic (8.78e-2)" "unprognostic (1.30e-2)" "unprognostic (2.39e-1)" "prognostic unfavorable (1.23e-5)" "unprognostic (1.75e-1)" "unprognostic (1.72e-1)" "unprognostic (3.00e-2)" "unprognostic (5.98e-2)" 4.2 5.6 5.0 2.7 5.3 3.1 4.1 4.8 5.8 4.3 4.2 5.3 2.6 5.0 2.9 5.3 5.0 2.1 7.5 5.0 5.6 3.5 5.5 2.9 4.7 4.5 4.7 4.4 8.3 2.2 5.8 2.5 4.9 3.4 3.4 1.1 5.5 3.8 24.7 4.7 4.0 3.1 4.7 4.8 6.5 14.4 5.4 2.9 3.1 9.1 4.8 4.8 3.9 5.7 21.6 35.9 4.4 8.7 2.0 4.2 13.8 6.8 4.9 11.1 11.1 33.6 15.1 17.7 28.8 3.9 11.6 7.4 17.4 14.9 11.7 26.1 36.6 17.4 5.7 26.8 14.5 34.0 9.8 5.1 12.9 6.5 21.2 4.6 11.3 28.0 35.1 9.0 9.6 27.3 13.4 12.4 16.0 47.3 34.4 19.2 8.2 25.1 14.1 12.1 25.8 9.2 0.7 21.4 12.5 7.3 9.3 13.9 6.0 7.3 9.0 8.6 23.4 20.1 32.8 31.4 9.1 29.8 6.3 0.0 3.3 0.0 9.1 5.3 12.9 12.7 8.9 9.0 6.8 10.1 13.1 9.9 0.7 12.5 3.4 23.6 11.7 5.7 5.0 5.3 4.8 5.8 5.0 5.6 4.5 4.7 4.9 4.7 5.4 5.7 5.5 3.2 4.8 3.6 7.6 8.2 15.0 7.6 10.2 4.3 4.8 7.4 5.1 5.7 4.8 3.7 2.1 8.1 12.0 1.7 7.9 13.3 27.4 6.3 4.3 4.9 12.1 4.6 4.2 15.3 7.0 5.1 9.2 2.7 4.5 5.6 5.0 5.1 7.5 1.7 4.3 5.0 2.0 3.3 3.7 3.9 5.3 4.1 3.6 2.8 7.1 4.8 9.2 4.0 3.4 13.1 5.0 6.8 8.2 27.6 1.1 10.2 6.1 2.4 0.0 6.1 12.6 35.7 42.9 7.5 10.7 1.8 5.4 8.2 7.7 9.6 PDHA1 PDHA ENSG00000131828 "Pyruvate dehydrogenase E1 subunit alpha 1" P08559 X 19343893-19361718 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism, Tricarboxylic acid cycle" Oxidoreductase "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 508.8;tongue: 770.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 479.9;Distal tubular cells: 354.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047487, HPA047864, HPA063053" Approved Supported Mitochondria "Intracellular and membrane" NA NA 100000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA047487: AB_2680066, HPA047864: AB_2680190, HPA063053: AB_2684931" "unprognostic (5.71e-3)" "unprognostic (2.46e-3)" "unprognostic (5.71e-2)" "unprognostic (3.36e-3)" "unprognostic (3.12e-2)" "unprognostic (2.27e-2)" "unprognostic (1.37e-2)" "unprognostic (4.28e-1)" "unprognostic (1.01e-1)" "unprognostic (7.01e-3)" "unprognostic (6.90e-2)" "unprognostic (8.68e-2)" "prognostic favorable (1.13e-7)" "unprognostic (3.72e-2)" "unprognostic (3.03e-1)" "unprognostic (1.92e-2)" "unprognostic (9.06e-2)" 93.0 69.0 62.1 37.9 66.9 88.1 63.1 66.2 91.5 55.9 84.4 112.6 87.0 53.1 78.9 76.8 49.1 29.3 508.8 68.2 67.0 174.1 118.3 47.2 36.6 64.5 62.7 50.6 83.4 161.0 48.7 43.1 65.0 48.4 104.4 90.1 109.7 63.4 459.0 60.9 82.1 51.8 59.6 49.3 121.8 24.0 67.4 52.3 64.5 770.2 59.1 61.7 56.1 71.1 124.9 151.4 107.9 114.2 102.3 77.7 131.6 83.8 74.6 170.2 130.7 216.6 78.2 212.2 60.6 102.0 226.7 159.0 334.2 145.8 178.1 70.1 186.1 104.8 264.0 194.2 107.8 170.3 82.8 100.9 132.8 157.3 154.4 85.6 105.3 129.8 94.2 87.2 120.7 164.5 142.7 173.5 110.0 227.4 261.7 145.2 180.9 260.3 298.0 125.1 59.7 62.6 134.1 167.8 158.1 229.8 177.1 118.1 65.4 87.6 78.6 240.9 108.6 73.3 82.0 140.5 82.4 117.2 77.4 99.9 87.4 65.3 72.3 119.9 88.9 103.4 69.4 79.5 115.7 82.1 67.7 72.0 15.5 98.1 109.1 76.9 84.4 89.6 62.1 66.9 66.2 91.5 68.2 67.0 64.5 62.7 65.0 59.6 67.4 71.1 34.1 44.8 44.4 18.6 30.7 29.8 59.7 135.4 25.0 59.0 37.0 29.3 479.9 87.2 74.8 152.6 33.3 105.0 32.5 73.0 354.1 88.8 2.5 41.2 33.7 36.8 41.9 55.8 21.2 59.8 120.7 49.2 49.5 36.9 42.6 39.7 18.2 76.3 73.2 25.2 24.6 64.4 71.2 26.8 30.5 4.1 35.4 32.5 56.9 9.4 40.8 49.0 26.8 13.0 11.5 47.4 52.5 40.6 43.3 47.1 88.6 213.7 33.1 69.1 32.9 37.5 51.7 51.1 25.3 45.2 33.4 133.4 31.6 25.4 130.3 55.8 PDHA2 PDHAL ENSG00000163114 "Pyruvate dehydrogenase E1 subunit alpha 2" P29803 4 95840093-95841464 "Citric acid cycle related proteins, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism, Tricarboxylic acid cycle" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 602 "testis: 60.2" "Group enriched" "Detected in some" 71 "Early spermatids: 426.6;Late spermatids: 288.3;Spermatocytes: 229.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047487, HPA047864, HPA063053" Approved Supported Mitochondria NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "HPA047487: AB_2680066, HPA047864: AB_2680190, HPA063053: AB_2684931" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 60.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 426.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 288.3 4.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 229.6 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PDP2 "KIAA1348, PPM2B, PPM2C2" ENSG00000172840 "Pyruvate dehyrogenase phosphatase catalytic subunit 2" Q9P2J9 16 66878589-66895754 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 22.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019950, HPA062059" Approved Approved Mitochondria NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 11: Alveolar cells - Smell perception" Mitochondria "HPA019950: AB_1855156, HPA062059: AB_2684671" "unprognostic (8.42e-2)" "unprognostic (1.09e-1)" "unprognostic (1.19e-2)" "unprognostic (1.31e-1)" "unprognostic (2.31e-2)" "unprognostic (5.44e-2)" "unprognostic (1.17e-1)" "unprognostic (4.90e-3)" "unprognostic (1.57e-1)" "unprognostic (7.24e-2)" "unprognostic (1.03e-1)" "unprognostic (1.39e-1)" "prognostic favorable (9.75e-7)" "unprognostic (1.89e-1)" "unprognostic (5.10e-1)" "unprognostic (3.20e-1)" "unprognostic (6.15e-2)" 6.0 2.6 3.6 1.8 4.6 1.5 3.6 6.9 5.2 2.0 7.7 3.8 5.4 2.6 3.4 3.7 3.4 2.0 1.8 3.6 4.3 9.2 8.6 3.4 2.6 6.2 4.6 7.4 4.5 6.1 3.0 4.0 6.8 3.8 4.1 5.0 3.6 2.6 2.5 2.1 3.2 2.1 3.5 2.0 3.0 3.8 5.7 2.5 9.3 4.1 3.0 2.1 2.2 4.3 9.8 11.7 7.1 14.1 18.7 9.6 8.9 5.0 19.2 11.3 17.0 23.9 6.7 13.5 6.9 6.9 10.8 12.1 20.8 11.3 10.9 3.2 10.5 6.8 5.9 15.9 10.1 8.8 11.5 7.4 8.3 16.1 16.6 12.3 4.9 14.9 13.3 9.5 10.3 6.3 17.1 6.2 8.4 6.5 14.7 16.7 9.9 21.4 6.0 10.3 14.3 8.0 15.9 6.5 6.0 5.5 8.7 4.3 4.6 7.0 9.2 4.2 7.5 16.6 16.9 13.4 9.5 6.9 7.0 1.1 0.2 1.2 3.8 0.1 3.1 1.0 1.8 3.2 0.8 2.1 2.6 3.0 0.7 4.2 0.1 0.5 0.6 1.3 3.6 4.6 6.9 5.2 3.6 4.3 6.2 4.6 6.8 3.5 5.7 4.3 2.5 9.6 22.9 8.1 3.1 5.2 6.4 1.3 6.2 9.6 5.8 4.2 5.1 8.6 3.1 9.2 14.6 12.8 3.3 13.3 7.9 3.4 0.2 3.5 3.2 3.3 3.6 0.8 8.8 2.9 2.2 4.1 3.1 4.3 6.3 14.4 7.1 20.5 2.4 5.0 7.6 4.2 2.0 1.3 0.4 2.4 3.1 1.2 3.6 3.7 0.4 8.1 7.2 4.5 4.3 3.4 6.6 4.5 4.5 8.9 7.4 9.9 1.2 6.7 0.0 5.9 2.7 12.6 5.7 8.0 2.4 3.6 3.4 4.0 5.5 6.5 PDPR PDP3 ENSG00000090857 "Pyruvate dehydrogenase phosphatase regulatory subunit" Q8NCN5 16 70114332-70162537 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 54.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048092, HPA070386" Uncertain Approved Mitochondria NA NA "Cluster 46: Basophils - DNA binding" "Cluster 71: Testis - DNA repair" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Mitochondria "HPA048092: AB_2680261, HPA070386: AB_2686263" "unprognostic (8.30e-2)" "unprognostic (1.32e-1)" "unprognostic (7.91e-2)" "unprognostic (1.52e-1)" "unprognostic (2.57e-1)" "unprognostic (9.04e-3)" "unprognostic (6.81e-2)" "unprognostic (2.67e-1)" "unprognostic (1.41e-1)" "unprognostic (1.18e-2)" "unprognostic (2.55e-1)" "unprognostic (2.90e-1)" "prognostic favorable (8.36e-4)" "unprognostic (8.85e-2)" "unprognostic (1.96e-2)" "unprognostic (2.17e-1)" "unprognostic (6.24e-2)" 11.5 12.6 10.7 8.1 13.3 15.9 11.3 14.7 11.4 13.1 9.8 14.5 9.1 14.1 11.9 8.1 12.8 6.7 14.7 10.7 11.4 16.3 8.6 9.6 11.1 11.8 12.4 13.5 12.3 10.2 10.4 9.0 11.8 10.9 11.8 12.1 10.3 9.6 23.2 12.2 13.7 15.1 10.6 15.4 12.0 19.1 12.5 15.8 13.0 13.6 12.5 13.8 9.8 13.9 6.9 19.4 17.9 33.0 32.6 20.9 12.1 11.1 19.4 17.4 13.1 25.1 13.4 14.4 19.1 35.8 16.1 26.7 26.4 24.1 20.3 3.5 9.1 35.8 12.7 17.6 9.3 39.9 27.9 28.0 22.6 25.1 23.0 25.2 18.7 26.6 24.6 6.6 15.3 20.8 25.3 23.3 27.8 4.9 10.0 49.0 18.5 14.9 13.8 16.3 8.3 12.3 30.2 6.2 8.2 24.2 24.4 12.4 10.9 20.4 27.3 17.6 17.9 15.4 17.9 50.9 9.1 13.8 13.5 1.6 1.5 1.4 1.4 1.5 2.0 0.9 1.1 1.3 1.6 1.5 1.3 1.5 1.1 0.9 1.5 1.5 1.3 1.0 10.7 13.3 14.7 11.4 10.7 11.4 11.8 12.4 11.8 10.6 12.5 13.9 12.6 22.4 18.2 18.6 13.0 2.8 4.9 3.5 18.2 21.6 14.2 12.1 19.2 17.2 9.1 1.8 31.3 7.7 16.0 12.1 5.9 5.3 54.4 13.7 16.0 17.4 4.9 17.4 18.0 6.7 7.8 16.1 11.7 17.1 18.3 23.9 17.2 11.2 16.4 32.0 20.3 10.0 4.1 17.8 3.5 20.8 10.8 15.7 7.2 10.3 12.2 11.2 15.5 9.5 13.9 6.8 6.1 16.6 11.7 10.3 11.6 4.4 12.7 20.8 19.7 22.7 11.5 10.8 15.4 11.1 1.8 4.9 11.9 12.7 14.5 4.6 PDZRN4 "DKFZp434B0417, FLJ33777, IMAGE5767589, LNX4" ENSG00000165966 "PDZ domain containing ring finger 4" Q6ZMN7 12 41188320-41574745 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 10.9;seminal vesicle: 17.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 371.6;Inhibitory neurons: 125.6;Oligodendrocyte precursor cells: 561.9" "Cancer enhanced" "Detected in some" "thyroid cancer: 3.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 9 "U-266/70: 4.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042101 Enhanced Approved Mitochondria NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Mitochondria "HPA042101: AB_2732496" "unprognostic (6.74e-2)" "unprognostic (6.86e-2)" "unprognostic (3.82e-2)" "unprognostic (2.88e-2)" "unprognostic (1.49e-1)" "unprognostic (5.34e-2)" "unprognostic (2.48e-2)" "unprognostic (1.38e-2)" "unprognostic (8.19e-2)" "unprognostic (7.85e-3)" "unprognostic (1.69e-1)" "unprognostic (2.42e-1)" "unprognostic (7.44e-2)" "unprognostic (1.90e-3)" "unprognostic (1.80e-1)" "unprognostic (7.33e-2)" "unprognostic (1.41e-3)" 1.2 0.9 1.5 1.1 2.5 0.0 1.9 0.1 2.3 2.2 0.0 10.9 0.8 0.9 2.2 3.8 2.2 1.7 0.4 1.5 0.9 0.5 0.6 0.3 0.0 1.3 3.3 1.9 0.4 0.1 0.4 4.0 2.2 6.6 3.1 1.0 0.3 17.8 0.3 0.5 2.9 2.5 1.3 0.2 3.3 2.4 1.4 0.0 0.3 1.9 0.3 3.9 2.6 1.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 2.5 0.1 2.3 1.5 0.9 1.3 3.3 2.2 1.3 1.4 1.9 0.1 0.0 0.0 37.5 0.3 0.8 0.0 0.0 2.8 9.8 0.0 0.1 0.4 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.7 0.1 0.4 0.3 0.0 0.0 371.6 0.0 0.2 17.3 1.1 0.0 0.0 19.8 1.4 0.0 0.4 0.0 125.6 0.0 0.0 0.0 0.3 1.6 28.0 0.2 0.0 5.6 0.0 0.4 0.0 561.9 13.7 0.0 0.0 56.4 1.2 0.1 0.0 0.0 0.7 1.1 0.0 0.1 5.7 0.1 0.2 0.8 0.6 0.4 0.0 34.1 0.0 0.1 PET100 C19orf79 ENSG00000229833 "PET100 cytochrome c oxidase chaperone" P0DJ07 19 7629793-7631956 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067288 Approved Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 16: Pancreatic endocrine cells - Mixed function" Mitochondria "HPA067288: AB_2732762" "unprognostic (7.02e-2)" "prognostic favorable (6.81e-4)" "unprognostic (1.57e-1)" "unprognostic (9.87e-3)" "unprognostic (2.14e-1)" "unprognostic (4.18e-2)" "unprognostic (1.70e-1)" "prognostic favorable (7.97e-4)" "unprognostic (4.89e-1)" "unprognostic (2.88e-3)" "unprognostic (2.49e-2)" "unprognostic (2.33e-2)" "unprognostic (4.09e-2)" "unprognostic (1.37e-1)" "unprognostic (1.25e-1)" "unprognostic (2.66e-2)" "prognostic favorable (2.44e-4)" 35.0 45.6 77.8 38.3 76.8 85.2 38.8 77.3 125.7 28.0 81.7 39.5 38.1 25.1 46.1 40.3 23.4 6.6 70.0 77.0 77.2 49.7 65.5 28.4 26.6 76.8 78.1 23.0 33.1 75.9 41.5 23.0 77.3 29.9 28.1 64.8 43.3 22.8 79.3 31.3 33.0 17.0 75.5 36.5 45.8 31.1 76.7 75.9 34.7 65.1 31.9 27.3 29.5 79.0 72.2 63.5 112.2 67.9 54.9 39.3 40.7 60.0 34.6 40.9 39.7 60.6 47.3 48.3 102.8 46.3 49.8 61.9 52.3 55.4 34.1 110.5 108.0 69.1 136.8 96.5 27.4 118.8 62.2 44.4 35.4 27.6 28.6 64.5 59.2 113.5 50.5 179.4 43.2 80.7 128.1 182.0 73.0 83.2 141.0 77.0 64.4 113.6 85.8 86.8 63.3 74.3 79.4 71.5 68.3 69.6 51.9 153.2 63.6 31.8 39.1 64.4 90.1 157.5 134.0 86.0 58.1 89.3 38.7 806.4 481.1 576.6 241.3 408.1 227.5 338.5 276.8 256.6 309.2 332.5 256.1 268.1 468.2 227.4 370.5 538.5 390.0 501.2 77.8 76.8 77.3 125.7 77.0 77.2 76.8 78.1 77.3 75.5 76.7 79.0 109.5 150.6 189.0 6.2 137.2 50.2 39.8 194.1 87.6 52.7 136.8 109.6 54.1 197.3 150.6 259.3 22.9 126.7 159.3 275.4 215.2 215.7 51.1 156.7 101.9 93.3 191.5 238.4 4.5 318.3 128.9 82.6 144.3 160.7 106.9 69.0 171.0 542.3 171.7 18.5 4.5 255.4 158.7 236.4 103.8 47.3 101.5 161.2 113.8 10.3 228.8 123.0 130.7 4.5 8.4 351.4 302.4 83.1 198.9 57.0 341.9 295.9 160.2 96.5 85.5 52.0 80.4 126.5 84.0 127.0 59.1 178.8 131.0 30.1 213.1 53.0 PGAM5 "BXLBv68, MGC5352" ENSG00000247077 "PGAM family member 5, mitochondrial serine/threonine protein phosphatase" Q96HS1 12 132710819-132722734 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Necrosis Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036978, HPA036979, CAB068215" Enhanced Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB068215: AB_2665674, HPA036978: AB_10964347, HPA036979: AB_10960559" "unprognostic (9.57e-2)" "unprognostic (2.00e-2)" "unprognostic (3.83e-2)" "unprognostic (3.11e-2)" "unprognostic (3.46e-1)" "unprognostic (1.39e-1)" "prognostic unfavorable (1.13e-6)" "unprognostic (3.32e-2)" "unprognostic (1.47e-1)" "unprognostic (5.67e-2)" "unprognostic (1.23e-1)" "unprognostic (6.92e-2)" "unprognostic (6.42e-3)" "unprognostic (1.63e-2)" "unprognostic (1.71e-1)" "unprognostic (1.19e-1)" "unprognostic (5.53e-2)" 10.5 17.7 13.0 17.0 12.7 16.3 9.7 12.7 17.0 9.8 10.1 16.1 15.2 10.9 6.6 23.9 12.4 8.7 20.0 19.0 12.5 14.3 28.9 9.3 21.2 9.3 9.7 7.2 25.8 10.7 9.9 10.7 10.1 9.4 11.3 6.0 15.5 11.5 33.2 17.1 13.2 11.3 7.9 12.8 13.3 16.5 10.8 14.8 11.6 19.0 16.1 15.6 11.8 11.3 72.2 134.3 28.2 79.5 19.4 15.6 66.1 37.4 22.0 59.1 33.0 168.6 40.2 92.3 67.2 31.2 30.4 61.2 132.9 67.5 24.1 47.3 106.7 110.7 61.6 89.2 44.0 105.8 61.8 19.4 48.8 69.0 73.6 19.3 43.6 73.4 143.3 36.9 23.5 128.5 144.5 105.7 108.0 61.8 94.4 109.4 31.2 73.3 38.4 97.4 102.8 58.0 62.2 86.1 38.9 22.2 108.9 57.5 38.2 29.9 65.5 60.6 89.9 77.2 124.8 133.5 38.8 85.3 51.1 4.9 1.1 0.3 1.1 1.2 1.8 1.7 1.3 1.3 1.0 1.7 1.3 1.7 0.9 1.6 1.7 3.3 1.1 0.8 13.0 12.7 12.7 17.0 19.0 12.5 9.3 9.7 10.1 7.9 10.8 11.3 6.6 3.2 6.1 3.9 8.9 11.5 16.7 2.6 2.2 9.5 7.8 5.5 15.1 15.7 1.5 5.5 14.6 7.6 11.9 11.7 5.9 5.8 14.5 6.3 6.3 7.0 13.1 5.0 5.1 7.9 14.4 4.9 4.1 9.3 0.0 7.1 5.7 22.4 7.3 6.7 3.9 8.9 2.0 6.9 5.8 20.6 5.9 4.7 3.6 1.9 5.3 4.4 3.1 2.0 2.3 7.5 6.9 6.8 9.7 19.5 5.2 11.5 4.5 12.9 6.6 8.0 6.4 15.1 10.1 10.8 17.3 6.2 7.4 9.2 15.7 16.1 PGAP4 "C9orf125, MGC12992, TMEM246" ENSG00000165152 "Post-GPI attachment to proteins GalNAc transferase 4" Q9BRR3 9 101473170-101533537 "Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 16 "Cardiomyocytes: 52.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTCEpi: 25.5;hTERT-RPE1: 28.8;OE19: 48.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011318, HPA054041" Uncertain Approved Mitochondria NA Yes "Cluster 45: Intestine - Brush border" "Cluster 21: OE19 - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA011318: AB_2668482, HPA054041: AB_2682353" "unprognostic (2.58e-2)" "unprognostic (4.76e-2)" "unprognostic (5.52e-1)" "unprognostic (2.81e-3)" "unprognostic (2.72e-2)" "unprognostic (9.15e-2)" "unprognostic (1.20e-3)" "unprognostic (2.26e-1)" "unprognostic (1.11e-1)" "unprognostic (4.24e-1)" "unprognostic (3.51e-2)" "unprognostic (2.09e-1)" "prognostic favorable (1.55e-8)" "unprognostic (1.62e-1)" "unprognostic (1.91e-1)" "unprognostic (2.50e-1)" "unprognostic (9.16e-2)" 3.9 10.3 21.5 2.2 21.3 0.5 2.4 18.9 26.2 16.6 4.5 13.4 8.4 7.1 3.7 14.4 13.7 6.8 30.4 24.9 26.1 4.7 2.4 5.4 0.4 17.9 13.4 19.5 11.1 16.6 12.3 0.6 26.1 6.9 11.2 9.9 6.1 9.4 4.8 12.0 7.6 6.7 9.6 1.6 16.0 2.8 19.2 0.9 4.2 6.1 2.4 6.4 11.9 20.3 0.0 14.6 11.3 0.0 0.3 0.2 0.0 9.8 14.1 7.0 13.8 0.7 7.8 0.0 3.2 17.9 0.8 23.1 0.0 16.1 4.2 0.0 5.8 8.1 10.3 0.0 0.5 0.0 0.0 6.2 25.5 0.0 3.8 28.8 0.1 0.0 0.0 0.0 14.3 0.0 0.0 0.0 14.0 48.1 0.0 0.0 5.7 0.0 10.5 2.7 18.9 17.8 5.5 0.0 0.0 2.7 0.0 13.8 0.0 10.7 6.6 0.0 0.0 1.0 0.0 0.0 15.2 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.5 21.3 18.9 26.2 24.9 26.1 17.9 13.4 26.1 9.6 19.2 20.3 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.1 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PGM2L1 "BM32A, FLJ32029" ENSG00000165434 "Phosphoglucomutase 2 like 1" Q6PCE3 11 74330316-74398433 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Isomerase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 90.1;Exocrine glandular cells: 124.5;Pancreatic endocrine cells: 140.1;Respiratory ciliated cells: 95.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 16.6;LHCN-M2: 19.9;RH-30: 18.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056995, HPA060948" Enhanced Approved Mitochondria No No 140000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 1: Pancreatic cells - Digestion" Mitochondria "HPA056995: AB_2683305, HPA060948: AB_2684394" "unprognostic (7.44e-3)" "unprognostic (1.33e-1)" "unprognostic (7.28e-3)" "unprognostic (8.91e-2)" "unprognostic (6.16e-2)" "unprognostic (1.55e-1)" "unprognostic (7.16e-6)" "unprognostic (1.43e-1)" "unprognostic (1.95e-1)" "unprognostic (5.97e-3)" "unprognostic (1.70e-2)" "unprognostic (2.98e-1)" "unprognostic (9.33e-3)" "unprognostic (3.71e-1)" "unprognostic (1.97e-1)" "unprognostic (3.04e-1)" "unprognostic (1.03e-2)" 1.9 2.6 17.6 3.7 22.1 3.2 1.9 0.0 21.5 4.9 0.0 3.2 1.3 4.4 0.8 1.0 3.2 3.3 1.1 23.1 16.2 1.6 1.0 1.8 3.0 1.9 4.5 0.9 3.1 0.7 3.9 1.1 2.2 2.9 3.5 2.6 2.6 1.3 5.9 0.7 1.5 4.0 0.3 1.5 2.1 1.3 5.7 8.1 2.7 11.1 2.7 6.4 1.9 7.8 2.7 3.8 14.5 2.7 4.3 1.9 0.4 3.5 2.6 3.0 3.3 1.4 6.8 0.3 8.5 2.3 5.3 1.3 2.9 0.7 2.8 1.1 1.5 2.1 2.0 1.1 0.5 2.4 3.2 1.0 0.7 6.8 1.2 3.2 16.6 5.0 2.8 1.8 19.9 0.3 9.9 2.1 2.9 2.0 3.3 3.1 18.9 0.1 7.8 0.5 0.7 2.9 5.7 1.3 2.6 3.9 0.2 0.4 14.0 6.6 6.0 2.7 3.7 2.4 3.8 0.3 0.6 3.4 1.6 1.2 0.3 0.5 0.9 0.3 1.3 1.1 1.6 1.1 0.2 0.8 1.5 0.8 0.3 1.4 0.2 0.8 3.9 0.5 17.6 22.1 0.0 21.5 23.1 16.2 1.9 4.5 2.2 0.3 5.7 7.8 19.6 6.4 6.4 8.5 20.9 7.6 41.2 14.3 10.8 23.9 26.5 19.4 7.3 17.2 30.2 9.2 16.7 0.6 17.6 13.8 5.9 37.4 14.1 28.1 23.5 32.1 11.9 47.5 90.1 124.5 5.3 21.0 7.1 25.5 8.2 16.1 29.3 1.0 5.4 8.4 64.8 16.2 18.3 23.0 21.6 3.6 2.5 9.9 16.0 20.6 4.6 4.4 12.3 14.6 7.1 140.1 9.3 3.8 13.4 50.4 4.2 5.3 95.4 11.0 26.3 21.3 16.7 34.2 21.2 9.0 5.3 0.1 25.0 8.8 20.9 55.6 PHB PHB1 ENSG00000167085 Prohibitin P35232 17 49404052-49414901 "Plasma proteins, Predicted intracellular proteins" "DNA synthesis, Host-virus interaction" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 473.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CACO-2: 749.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003280 Supported Supported Mitochondria "Intracellular and membrane" NA NA 360000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 18: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA003280: AB_1855732" "unprognostic (2.31e-2)" "unprognostic (5.70e-2)" "unprognostic (1.19e-2)" "unprognostic (7.88e-3)" "unprognostic (8.33e-2)" "prognostic unfavorable (1.58e-4)" "prognostic unfavorable (9.91e-4)" "unprognostic (5.81e-2)" "unprognostic (4.40e-2)" "unprognostic (3.53e-2)" "unprognostic (1.67e-1)" "unprognostic (7.36e-2)" "prognostic favorable (3.77e-4)" "unprognostic (5.10e-2)" "unprognostic (1.77e-1)" "unprognostic (2.71e-2)" "unprognostic (3.09e-3)" 81.6 88.4 39.2 23.3 42.2 19.8 77.4 44.2 49.8 55.3 54.0 104.5 52.6 68.0 34.1 88.6 55.7 26.9 147.0 40.6 44.4 143.4 120.4 59.0 27.0 43.9 42.5 59.7 62.5 70.1 51.1 33.1 44.1 67.2 60.0 12.1 135.9 44.7 138.1 67.5 68.0 35.7 40.9 61.1 79.7 33.5 41.9 26.2 61.5 98.5 26.8 75.2 59.4 46.0 86.0 339.1 46.4 96.9 81.9 48.3 111.8 69.8 72.3 175.1 122.4 749.5 80.2 119.2 88.1 60.0 67.3 63.4 151.7 135.3 128.4 72.9 327.1 77.7 122.8 361.8 53.0 109.6 58.1 54.9 125.9 130.9 41.6 45.7 87.6 68.6 112.7 27.6 77.5 224.0 106.0 118.5 99.9 135.9 311.1 74.9 144.0 103.8 144.0 116.1 122.1 75.9 35.4 59.1 113.7 71.7 112.2 33.4 58.9 96.3 124.7 78.4 98.4 35.3 65.7 59.1 58.0 125.6 110.7 11.7 45.9 13.4 61.6 53.4 80.5 61.2 56.6 56.3 62.3 46.7 59.4 59.7 8.9 69.0 59.5 155.1 61.4 79.8 39.2 42.2 44.2 49.8 40.6 44.4 43.9 42.5 44.1 40.9 41.9 46.0 88.5 48.1 46.8 8.8 78.3 117.5 147.5 182.6 70.0 44.8 135.7 180.0 8.4 100.1 101.9 84.6 37.5 230.2 144.4 220.8 406.9 233.1 14.0 93.4 85.5 92.6 131.9 77.2 7.8 158.6 278.7 87.8 74.9 131.0 73.0 124.6 61.4 101.8 228.1 21.9 10.0 281.7 223.8 51.9 87.9 24.7 89.5 70.9 158.3 1.9 120.3 83.1 88.6 11.1 15.3 162.8 139.8 115.1 93.0 242.8 151.4 473.6 68.0 42.1 52.6 72.8 306.5 18.0 47.3 107.6 124.0 152.4 75.9 159.9 337.2 161.9 PHB2 "Bap37, BCAP37, p22, REA" ENSG00000215021 "Prohibitin 2" Q99623 12 6965327-6970780 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB014889, CAB026335, HPA039874" Supported Enhanced Mitochondria NA NA 77000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 5: NTERA-2 - Transcription" "Cluster 32: Non-specific - Translation" Mitochondria "CAB014889: , CAB026335: AB_2283865, HPA039874: AB_2616448" "unprognostic (4.64e-3)" "unprognostic (4.32e-2)" "unprognostic (9.65e-2)" "prognostic unfavorable (3.80e-4)" "unprognostic (3.07e-3)" "unprognostic (1.67e-1)" "unprognostic (2.53e-1)" "unprognostic (1.62e-1)" "unprognostic (1.98e-1)" "unprognostic (7.18e-2)" "unprognostic (1.46e-1)" "unprognostic (2.85e-1)" "unprognostic (1.04e-1)" "unprognostic (5.65e-2)" "unprognostic (1.07e-1)" "unprognostic (8.17e-2)" "unprognostic (5.61e-2)" 134.3 166.6 75.6 95.2 75.6 149.4 138.7 76.7 81.3 152.2 78.8 162.3 149.8 134.0 122.6 168.7 137.0 80.3 157.0 72.9 75.1 112.7 233.4 88.0 141.9 74.8 75.2 244.3 199.5 130.9 76.3 84.9 75.8 114.0 145.4 48.2 138.1 97.8 303.5 150.6 127.4 102.3 75.5 113.6 141.8 36.1 77.5 144.5 103.4 231.1 162.8 135.8 125.4 75.9 270.5 261.1 214.1 295.8 170.6 295.0 469.2 183.6 245.6 329.7 259.8 420.5 283.0 567.8 78.8 187.4 200.6 225.0 395.9 337.5 267.2 306.9 316.1 296.4 146.3 409.2 284.1 488.8 212.4 307.2 229.2 208.0 452.5 331.8 331.4 157.0 270.1 127.1 238.5 277.2 449.0 452.9 813.3 236.8 224.7 307.4 338.3 356.7 270.0 312.8 111.7 372.9 152.2 434.9 503.8 440.1 67.6 379.3 191.8 141.5 227.4 115.2 402.2 128.1 166.3 586.7 186.7 251.0 207.6 78.5 88.3 43.8 84.2 107.2 103.8 102.8 96.2 98.1 138.5 98.1 85.0 85.1 35.4 117.8 94.8 129.0 123.6 114.2 75.6 75.6 76.7 81.3 72.9 75.1 74.8 75.2 75.8 75.5 77.5 75.9 114.1 48.1 54.8 14.7 155.0 74.4 106.8 110.1 191.8 42.9 155.1 230.8 45.1 91.5 62.1 35.0 39.6 212.9 99.8 104.6 115.4 134.1 2.8 68.2 124.8 86.0 100.6 143.7 10.0 162.3 282.2 97.7 100.4 88.0 63.5 177.2 92.1 172.5 163.0 18.5 11.4 142.7 77.3 125.0 70.4 7.2 97.3 105.0 72.9 8.4 131.0 87.3 102.0 12.5 12.9 119.8 90.3 68.8 145.9 99.4 197.3 142.4 40.1 46.8 72.3 109.1 128.7 33.3 57.0 245.3 76.3 170.1 102.9 218.5 268.5 113.4 PHYKPL "AGXT2L2, MGC15875" ENSG00000175309 "5-phosphohydroxy-L-lysine phospho-lyase" Q8IUZ5 5 178208471-178232802 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Lyase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036461, HPA063608" Approved Approved Mitochondria Yes No 160000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 34: Non-specific - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" Mitochondria "HPA036461: AB_10670717, HPA063608: AB_2685059" "unprognostic (3.29e-3)" "unprognostic (2.60e-1)" "unprognostic (5.51e-2)" "unprognostic (9.75e-2)" "unprognostic (1.28e-1)" "unprognostic (1.47e-1)" "unprognostic (1.24e-1)" "unprognostic (1.06e-2)" "unprognostic (1.68e-2)" "unprognostic (3.29e-1)" "unprognostic (5.38e-2)" "unprognostic (1.02e-3)" "prognostic unfavorable (3.82e-5)" "unprognostic (3.66e-2)" "unprognostic (1.55e-1)" "unprognostic (1.02e-1)" "unprognostic (2.41e-3)" 23.2 10.6 7.4 16.4 8.2 14.9 14.0 6.8 8.6 12.3 8.3 23.9 20.7 14.3 15.8 11.1 13.9 14.4 15.5 6.7 8.3 17.5 42.2 15.8 24.5 11.4 8.3 12.5 15.6 13.7 5.2 16.3 10.0 13.7 30.8 3.4 13.8 12.0 19.6 10.7 24.8 18.5 7.6 17.2 15.5 5.9 9.5 25.1 19.7 18.7 23.6 13.7 9.6 11.7 9.6 3.8 9.0 3.6 21.6 17.4 13.9 5.6 6.2 7.6 11.8 9.7 11.7 13.0 18.4 17.6 9.7 6.2 7.7 14.3 8.5 24.0 8.7 15.6 18.0 7.1 35.1 9.2 11.4 19.6 15.0 9.3 22.4 14.9 24.9 18.6 11.8 26.7 11.3 13.1 13.1 5.5 1.9 11.5 12.4 9.1 4.3 25.0 13.4 8.3 5.7 5.4 9.2 5.2 9.4 10.2 5.5 7.4 9.9 7.8 7.0 5.1 6.2 18.8 5.5 7.2 2.2 9.2 5.2 16.7 41.7 36.9 20.3 46.8 20.4 28.4 22.2 22.9 53.4 26.3 27.3 22.2 9.2 23.7 47.2 70.9 28.6 33.2 7.4 8.2 6.8 8.6 6.7 8.3 11.4 8.3 10.0 7.6 9.5 11.7 23.1 19.2 14.3 31.6 63.0 10.7 43.1 16.1 25.0 21.9 17.2 14.5 17.4 37.1 13.0 23.9 25.0 18.4 72.5 96.1 19.6 24.6 21.7 13.2 27.7 26.2 19.2 30.7 20.7 18.6 20.2 33.4 76.9 13.8 12.7 38.4 31.1 30.1 31.7 15.2 17.9 40.8 6.1 37.1 22.9 55.3 42.6 43.3 24.9 36.5 61.1 25.0 70.0 29.1 45.2 15.1 64.5 25.2 51.4 30.3 119.2 43.1 13.6 26.4 13.1 34.5 23.6 37.2 25.9 14.6 10.4 22.0 58.9 36.3 39.2 36.6 PILRB "FDFACT1, FDFACT2" ENSG00000121716 "Paired immunoglobin like type 2 receptor beta" Q9UKJ0 7 100352176-100367733 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 134.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 221.1;neutrophil: 141.8" "Group enriched" "Detected in all" 8 "granulocytes: 221.1;monocytes: 75.5" "Cell line enhanced" "Detected in all" "SK-BR-3: 344.6" HPA026750 Approved Approved Mitochondria "Intracellular and membrane" NA Yes "Cluster 45: Eosinophils - Innate immune response" "Cluster 43: Testis - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" Mitochondria "HPA026750: AB_10670828" "unprognostic (8.33e-3)" "unprognostic (9.31e-2)" "unprognostic (1.32e-2)" "unprognostic (9.15e-2)" "unprognostic (1.02e-1)" "unprognostic (1.30e-1)" "unprognostic (3.62e-2)" "unprognostic (3.17e-1)" "unprognostic (1.20e-1)" "unprognostic (8.76e-2)" "unprognostic (2.54e-2)" "unprognostic (6.27e-2)" "prognostic unfavorable (1.42e-4)" "unprognostic (4.85e-3)" "unprognostic (1.66e-1)" "unprognostic (4.40e-2)" "unprognostic (3.35e-3)" 63.2 89.0 72.9 71.0 75.0 71.7 77.6 104.3 86.3 87.0 90.9 65.8 66.1 62.9 67.6 47.2 83.8 52.2 47.7 75.5 70.8 118.8 125.0 43.9 83.7 71.8 70.8 82.1 91.7 58.3 182.0 32.9 71.5 102.7 57.4 66.8 66.4 58.0 78.7 90.1 75.9 42.3 64.2 113.5 68.7 157.5 74.3 59.0 122.9 34.3 65.7 61.9 56.2 78.1 62.5 51.4 57.9 100.7 63.0 14.4 56.2 37.0 16.5 25.7 24.9 36.5 70.3 50.3 68.0 19.0 45.7 65.1 32.3 38.9 17.5 41.6 47.3 46.5 204.8 32.2 14.0 47.4 116.0 18.1 44.8 34.8 70.2 31.9 21.8 73.6 50.7 118.9 18.3 83.9 74.8 243.3 25.2 51.7 26.9 43.3 16.9 51.6 116.4 100.3 53.8 38.5 31.2 344.6 45.7 61.7 60.5 72.3 52.4 90.8 57.9 58.8 48.7 71.2 98.6 61.8 25.5 69.4 54.6 21.2 35.6 221.1 10.7 59.2 6.7 0.6 1.3 7.1 17.8 1.6 1.2 2.6 141.8 17.9 75.5 0.5 0.6 25.7 72.9 75.0 104.3 86.3 75.5 70.8 71.8 70.8 71.5 64.2 74.3 78.1 22.8 38.5 45.9 0.0 25.3 15.7 18.1 17.1 11.4 44.7 32.9 33.7 1.1 44.3 32.2 14.7 68.8 12.9 49.5 12.3 1.9 7.6 18.4 43.1 17.5 19.8 29.4 7.4 0.0 5.6 12.1 13.4 36.2 57.2 25.2 26.0 24.3 77.7 10.0 75.7 0.0 21.2 22.4 16.0 16.6 13.6 74.0 11.7 19.6 0.0 10.0 19.0 134.9 0.0 0.0 7.4 16.2 51.1 14.5 17.9 20.3 4.9 40.3 64.9 26.3 18.2 14.3 49.4 10.2 10.5 13.5 15.7 37.0 23.5 22.4 16.7 PITRM1 "hMP1, KIAA1104, MP1, PreP" ENSG00000107959 "Pitrilysin metallopeptidase 1" Q5JRX3 10 3137728-3172841 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 186.1;Late spermatids: 98.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006753, HPA006754" Enhanced Supported Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 18: U-2197 - ECM organization" "Cluster 34: Spermatids - Unknown function" Mitochondria "HPA006753: AB_1079624, HPA006754: AB_1079623" "unprognostic (1.83e-3)" "unprognostic (7.01e-3)" "unprognostic (2.19e-1)" "unprognostic (1.69e-1)" "unprognostic (3.20e-2)" "unprognostic (6.67e-2)" "unprognostic (1.55e-1)" "unprognostic (1.78e-1)" "unprognostic (6.31e-2)" "unprognostic (3.41e-1)" "unprognostic (1.00e-2)" "unprognostic (3.32e-1)" "unprognostic (7.10e-2)" "unprognostic (3.99e-1)" "unprognostic (5.80e-2)" "unprognostic (4.76e-3)" "unprognostic (2.08e-2)" 40.8 64.9 22.7 19.1 24.9 26.0 36.9 23.8 34.2 40.9 22.9 40.9 19.6 40.5 23.8 38.4 38.0 18.3 60.2 25.2 24.5 50.5 44.9 40.4 21.0 25.3 26.0 54.4 41.1 33.3 42.3 17.0 26.0 42.6 22.1 49.6 41.3 22.1 94.9 39.2 32.7 25.8 21.0 30.4 37.0 43.6 26.1 42.4 41.7 59.6 21.7 43.6 38.4 28.5 81.8 67.2 21.7 31.7 62.1 67.6 22.3 125.9 51.0 92.5 49.1 55.5 45.5 38.5 39.5 70.7 33.2 55.8 37.8 82.4 74.3 72.3 55.0 61.1 42.9 39.2 36.2 21.8 62.3 50.4 57.0 103.5 55.8 55.4 81.2 56.3 60.1 44.5 115.7 67.1 59.6 14.0 15.0 97.9 71.0 27.5 34.1 54.0 67.9 54.8 29.4 16.4 95.9 57.5 46.6 35.8 67.2 23.9 114.5 63.7 17.2 160.5 47.8 36.1 48.6 41.7 108.8 38.2 31.5 3.1 6.9 1.5 10.3 8.8 10.5 10.4 9.5 10.9 13.3 5.3 9.7 11.1 0.3 13.7 11.9 5.3 12.6 8.5 22.7 24.9 23.8 34.2 25.2 24.5 25.3 26.0 26.0 21.0 26.1 28.5 12.2 28.9 29.0 13.4 9.3 6.8 17.6 11.1 6.2 13.1 10.7 12.2 44.9 8.6 23.5 3.7 20.9 13.4 7.9 12.4 7.9 18.2 186.1 14.5 14.6 14.0 18.0 10.7 18.4 29.2 20.0 14.7 16.8 23.1 14.5 18.0 7.1 16.3 14.8 6.7 17.9 12.7 20.3 10.1 6.3 98.7 17.1 10.0 19.6 6.5 9.9 7.1 4.1 11.1 14.7 34.8 10.0 14.7 13.7 23.9 10.6 8.5 19.1 19.7 6.6 16.9 15.3 28.1 21.6 17.0 5.7 13.5 10.1 30.4 12.9 17.7 PJVK DFNB59 ENSG00000204311 Pejvakin Q0ZLH3 2 178451346-178462102 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Hearing "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 20.7" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Alveolar cells type 2: 9.1;Distal tubular cells: 3.9;Granulosa cells: 6.1;Theca cells: 4.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "plasmacytoid DC: 2.8" "Lineage enriched" "Detected in single" 5 "dendritic cells: 2.8" "Cell line enhanced" "Detected in many" "SuSa: 6.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042621 Approved Mitochondria No No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 68: Epididymis - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA042621: AB_10797503" "unprognostic (4.01e-2)" "unprognostic (4.28e-2)" "unprognostic (1.58e-2)" "unprognostic (2.64e-1)" "unprognostic (7.21e-3)" "unprognostic (9.36e-2)" "unprognostic (1.22e-1)" "unprognostic (1.14e-1)" "unprognostic (8.60e-3)" "unprognostic (4.57e-2)" "unprognostic (1.90e-3)" "unprognostic (9.13e-2)" "prognostic unfavorable (8.92e-4)" "unprognostic (1.22e-1)" "unprognostic (1.47e-1)" "unprognostic (2.41e-2)" "unprognostic (8.06e-3)" 3.0 1.8 6.9 1.3 7.2 1.4 4.8 6.9 10.7 2.7 6.9 1.9 1.2 3.9 7.3 1.2 2.8 2.9 1.4 7.0 7.0 3.2 2.8 1.5 1.9 7.6 7.3 7.1 1.3 1.1 4.1 1.2 7.5 2.8 1.2 6.4 2.7 3.0 3.5 4.2 1.4 2.0 7.3 1.4 1.2 20.7 7.1 1.2 2.5 0.9 1.7 1.9 1.4 7.7 0.2 1.8 2.3 1.9 3.0 3.1 1.2 1.5 1.4 1.2 2.0 0.7 3.1 2.1 1.5 0.9 1.0 0.9 1.7 1.0 0.9 0.7 0.6 0.7 2.9 0.4 3.0 0.6 0.2 3.2 2.2 1.4 3.2 3.8 1.5 4.1 0.4 1.3 1.5 0.5 2.1 1.3 2.8 0.2 0.8 2.7 1.7 1.3 2.0 1.0 1.6 1.3 0.5 0.3 0.6 6.8 0.7 0.7 1.0 1.5 0.6 0.4 0.1 4.3 2.8 0.7 0.7 1.1 0.6 0.1 0.1 0.0 0.1 0.1 0.2 0.3 0.2 0.1 0.0 0.5 0.5 0.3 0.4 0.2 0.0 2.8 0.0 0.0 6.9 7.2 6.9 10.7 7.0 7.0 7.6 7.3 7.5 7.3 7.1 7.7 1.6 6.4 9.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.0 2.4 0.0 0.0 1.8 1.8 0.0 1.1 0.5 0.0 3.9 1.4 0.0 1.8 2.6 0.4 0.0 0.0 0.0 0.9 0.5 1.4 0.0 1.6 0.0 6.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 2.6 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.6 4.7 0.0 0.0 PLAAT2 "FLJ20556, HRASLS2, PLAAT-2" ENSG00000133328 "Phospholipase A and acyltransferase 2" Q9NWW9 11 63552770-63563379 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 67.9" "Cell type enhanced" "Detected in single" "dendritic cells: 2.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 8 "memory B-cell: 17.3;naive B-cell: 8.2" "Lineage enriched" "Detected in many" 10 "B-cells: 17.3" "Cell line enriched" "Detected in some" 8 "U-266/70: 128.9" HPA058997 Approved Approved Mitochondria NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Mitochondria "HPA058997: AB_2683874" "unprognostic (4.76e-2)" "prognostic favorable (6.87e-4)" "unprognostic (1.20e-1)" "unprognostic (3.07e-2)" "unprognostic (1.43e-1)" "unprognostic (1.43e-1)" "unprognostic (1.82e-1)" "unprognostic (1.53e-1)" "unprognostic (9.69e-2)" "unprognostic (3.91e-3)" "prognostic unfavorable (5.27e-5)" "unprognostic (1.56e-1)" "unprognostic (2.29e-1)" "unprognostic (1.38e-2)" "unprognostic (2.51e-1)" "unprognostic (2.43e-1)" "unprognostic (1.57e-2)" 0.3 0.0 0.6 0.8 0.6 0.1 9.1 0.5 0.9 0.9 0.3 11.2 67.9 0.3 1.2 1.5 4.7 0.6 0.2 0.5 0.5 8.6 4.6 3.6 0.3 0.7 0.6 0.2 0.0 0.0 0.2 0.2 0.6 0.4 13.7 0.0 0.9 0.5 0.0 0.3 42.5 0.3 0.5 0.7 12.4 0.5 0.6 0.3 0.9 0.0 0.3 1.3 0.2 1.1 0.4 1.7 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.4 0.1 0.3 15.6 0.0 0.9 0.0 0.4 1.0 0.6 0.2 0.1 0.2 0.0 0.1 1.0 0.1 0.2 0.0 0.1 0.1 1.2 0.3 0.0 0.7 0.0 0.0 0.0 6.7 0.0 0.0 0.2 0.3 0.1 8.7 1.9 0.0 0.0 1.5 0.6 0.0 0.0 0.2 0.1 4.0 0.0 0.1 2.2 0.1 0.0 0.0 0.0 0.1 0.0 128.9 16.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.9 17.3 0.2 1.0 0.1 8.2 0.2 0.7 0.1 1.6 0.0 0.9 0.0 3.9 0.6 0.6 0.5 0.9 0.5 0.5 0.7 0.6 0.6 0.5 0.6 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 PLAAT3 "AdPLA, H-REV107-1, HRASLS3, HREV107, HREV107-3, MGC118754., PLA2G16, PLAAT-3" ENSG00000176485 "Phospholipase A and acyltransferase 3" P53816 11 63573195-63616883 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Host-virus interaction, Lipid degradation, Lipid metabolism" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 318.7;brain: 394.8" "Cell type enhanced" "Detected in some" "Adipocytes: 80.5;Cardiomyocytes: 151.9;Cytotrophoblasts: 137.4;Extravillous trophoblasts: 365.5;Hofbauer cells: 71.0;Syncytiotrophoblasts: 290.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 187.8" "Group enriched" "Detected in all" 6 "dendritic cells: 187.8;T-cells: 55.0" "Cell line enhanced" "Detected in many" "A549: 135.1;ASC diff: 148.2;CAPAN-2: 247.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011749, HPA058997" Approved Supported Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 38: Extravillous trophoblasts - Unknown function" Mitochondria "HPA011749: , HPA058997: AB_2683874" "unprognostic (5.18e-2)" "unprognostic (3.67e-2)" "unprognostic (7.92e-2)" "unprognostic (3.89e-2)" "unprognostic (1.94e-1)" "unprognostic (1.78e-1)" "unprognostic (1.13e-1)" "unprognostic (3.06e-2)" "unprognostic (6.97e-2)" "unprognostic (1.14e-1)" "prognostic unfavorable (5.58e-6)" "unprognostic (6.38e-2)" "unprognostic (1.93e-3)" "unprognostic (1.62e-1)" "unprognostic (1.75e-1)" "prognostic favorable (2.54e-5)" "unprognostic (2.35e-1)" 318.7 36.2 208.5 10.2 287.0 3.1 166.8 234.7 261.6 13.3 142.8 32.8 8.7 17.6 26.6 13.2 33.0 29.1 103.0 197.7 215.3 65.0 76.5 37.6 11.6 283.0 250.7 73.4 32.4 28.6 33.4 40.3 279.8 16.4 7.6 26.6 28.9 29.9 108.9 10.7 21.8 15.8 241.2 15.9 31.9 54.7 237.1 7.1 41.2 118.7 4.4 26.7 9.6 394.8 87.7 135.1 3.7 0.2 148.2 25.1 24.1 3.2 26.9 22.3 11.2 30.8 247.1 0.0 55.3 6.9 72.4 4.4 127.4 6.8 16.9 108.0 5.0 1.3 33.3 5.4 87.8 0.0 1.3 15.2 0.7 55.4 2.2 88.1 35.4 0.0 1.6 9.6 24.0 15.3 0.2 0.6 10.8 55.0 43.0 0.0 0.0 8.7 71.2 12.3 1.7 9.7 18.0 51.5 28.7 54.6 111.6 4.5 52.2 10.0 0.7 34.0 7.7 39.6 28.0 0.3 40.1 0.0 1.0 0.1 21.1 0.1 55.0 9.1 30.3 7.4 12.1 40.5 6.4 1.2 3.9 30.0 1.3 21.0 0.6 187.8 9.3 27.2 208.5 287.0 234.7 261.6 197.7 215.3 283.0 250.7 279.8 241.2 237.1 394.8 80.5 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 151.9 0.0 0.0 0.0 0.0 137.4 18.6 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.0 365.5 14.7 0.0 0.0 0.0 0.0 0.0 0.0 71.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 0.0 290.6 2.0 0.0 0.0 0.0 PLEKHJ1 FLJ10297 ENSG00000104886 "Pleckstrin homology domain containing J1" Q9NW61 19 2230084-2237704 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 356.3;Proximal enterocytes: 372.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048989 Approved Approved Mitochondria No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA048989: AB_2680590" "unprognostic (5.11e-1)" "unprognostic (4.84e-3)" "unprognostic (2.33e-1)" "unprognostic (9.82e-2)" "unprognostic (1.38e-1)" "unprognostic (7.83e-2)" "unprognostic (2.03e-3)" "unprognostic (2.89e-3)" "unprognostic (1.51e-1)" "unprognostic (1.71e-1)" "unprognostic (9.03e-3)" "unprognostic (3.49e-2)" "prognostic favorable (1.10e-5)" "prognostic favorable (6.99e-4)" "unprognostic (5.67e-2)" "unprognostic (1.15e-1)" "unprognostic (6.26e-3)" 43.4 64.1 41.8 26.4 39.0 38.3 40.5 40.4 51.3 38.8 40.6 109.2 105.2 33.6 18.0 61.3 30.0 19.5 77.6 40.2 39.8 101.1 78.7 42.0 39.3 41.6 41.7 44.1 94.1 14.7 36.4 19.7 43.6 43.4 34.0 4.7 52.2 14.3 88.9 51.7 101.5 12.2 40.2 61.4 99.7 68.0 45.3 27.8 69.2 33.2 24.0 40.8 39.7 38.8 93.9 38.2 68.2 83.0 21.8 28.3 40.3 51.6 24.1 54.1 48.9 98.1 43.1 88.4 42.1 35.6 34.7 71.6 65.4 34.0 16.1 90.8 83.7 46.3 44.5 129.0 34.7 98.6 68.9 41.6 34.2 25.8 23.1 21.5 34.9 75.4 99.5 101.0 39.8 61.3 97.0 88.0 122.6 55.6 52.1 114.7 47.5 108.8 55.7 92.0 170.2 94.1 32.6 58.7 104.5 27.3 78.6 98.2 36.6 23.0 68.7 69.7 56.7 147.3 97.2 101.3 67.4 94.8 30.1 88.2 76.4 129.6 86.9 98.2 77.1 118.8 85.9 91.8 80.8 143.2 69.0 67.2 66.1 53.8 108.3 159.0 112.6 97.2 41.8 39.0 40.4 51.3 40.2 39.8 41.6 41.7 43.6 40.2 45.3 38.8 25.9 38.5 21.1 9.8 67.0 34.8 54.6 61.5 20.5 22.0 60.0 68.1 40.0 87.2 37.8 46.0 16.7 89.8 65.8 356.3 164.4 121.1 68.5 33.2 33.4 26.7 54.0 39.8 12.1 179.5 99.3 46.0 121.8 35.2 18.4 117.1 25.7 49.2 95.4 25.2 11.7 228.5 95.6 43.9 33.3 115.6 47.2 48.1 30.2 9.4 74.7 31.9 65.9 12.1 7.6 146.6 233.3 35.3 49.0 82.2 372.5 148.4 29.1 22.7 32.9 18.9 47.5 93.7 100.7 47.2 42.6 47.7 52.6 81.4 254.1 58.4 PLEKHO1 "CKIP-1, OC120" ENSG00000023902 "Pleckstrin homology domain containing O1" Q53GL0 1 150149183-150164720 "Predicted intracellular proteins" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 202.3" "Cell type enhanced" "Detected in many" "Early spermatids: 245.9;Langerhans cells: 159.2;Late spermatids: 390.5;Macrophages: 147.9;monocytes: 151.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061018 Supported Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA061018: AB_2684416" "unprognostic (1.41e-2)" "unprognostic (7.04e-3)" "unprognostic (2.01e-2)" "unprognostic (1.78e-2)" "unprognostic (3.23e-2)" "unprognostic (4.77e-2)" "unprognostic (1.62e-2)" "unprognostic (8.33e-2)" "unprognostic (3.84e-2)" "unprognostic (3.18e-2)" "unprognostic (8.71e-2)" "unprognostic (3.21e-1)" "prognostic unfavorable (6.47e-11)" "unprognostic (9.30e-2)" "unprognostic (1.72e-1)" "unprognostic (1.87e-1)" "unprognostic (6.52e-2)" 27.7 43.2 49.9 53.9 50.1 17.9 22.6 52.8 61.6 32.3 45.5 202.3 17.8 50.7 5.2 17.5 43.5 20.6 59.3 49.5 47.9 15.9 8.7 34.9 49.5 49.8 48.1 28.1 5.1 4.1 14.9 15.1 48.0 45.5 11.5 4.2 11.0 16.2 39.6 11.2 58.4 40.4 48.9 59.9 55.8 83.2 48.0 33.9 13.0 15.2 26.0 97.5 23.6 48.9 14.3 3.4 46.3 36.0 14.4 12.7 3.8 24.8 32.9 31.8 28.1 1.0 0.4 0.4 4.7 28.5 23.9 1.2 23.3 1.1 10.3 86.7 12.1 2.8 1.9 8.9 27.1 20.0 77.7 18.5 1.0 39.8 6.2 30.6 30.6 38.5 5.4 35.9 43.9 6.7 76.0 40.0 43.7 0.0 6.4 68.1 25.2 16.2 5.6 4.1 28.8 46.9 2.0 0.2 18.7 22.1 2.4 19.4 43.4 20.8 24.1 21.9 30.1 14.0 0.4 9.2 83.4 0.2 8.2 2.6 25.9 0.5 5.6 24.8 6.0 20.0 8.2 5.9 20.1 17.2 5.6 4.7 30.9 4.1 23.4 27.3 6.7 9.2 49.9 50.1 52.8 61.6 49.5 47.9 49.8 48.1 48.0 48.9 48.0 48.9 23.5 35.3 8.9 32.3 65.1 21.5 92.7 2.9 4.6 7.9 11.8 17.9 36.4 2.8 2.9 0.0 0.0 1.7 97.5 0.5 1.9 8.8 245.9 17.9 50.2 58.9 17.8 4.2 13.5 7.8 3.3 29.4 4.6 22.0 5.7 24.5 42.5 1.8 107.1 8.4 24.3 0.9 10.2 85.5 159.2 390.5 17.4 147.9 24.9 21.5 151.1 34.0 23.7 9.0 1.6 10.7 0.0 24.5 23.7 50.1 0.2 0.5 1.3 6.2 72.3 7.5 105.0 122.5 17.5 2.9 14.2 1.5 45.6 8.6 0.4 23.0 PLGRKT "AD025, C9orf46, FLJ14688, MDS030, Plg-RKT" ENSG00000107020 "Plasminogen receptor with a C-terminal lysine" Q9HBL7 9 5357971-5437925 "Predicted intracellular proteins" "Chemotaxis, Inflammatory response, Plasminogen activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 191.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 244.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 247.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008214, HPA011144" Supported Uncertain Mitochondria NA NA "Cluster 10: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA008214: AB_1078363, HPA011144: AB_1078364" "prognostic favorable (5.56e-4)" "unprognostic (5.31e-2)" "unprognostic (2.96e-2)" "unprognostic (9.67e-2)" "unprognostic (1.05e-1)" "unprognostic (2.12e-2)" "unprognostic (1.72e-1)" "unprognostic (1.89e-2)" "unprognostic (3.85e-2)" "unprognostic (5.45e-3)" "unprognostic (2.19e-2)" "unprognostic (1.84e-1)" "prognostic favorable (5.09e-5)" "unprognostic (1.45e-2)" "unprognostic (1.47e-1)" "unprognostic (1.01e-1)" "unprognostic (2.02e-1)" 18.9 17.9 9.6 20.2 10.5 13.6 25.4 10.3 13.8 18.1 15.3 41.2 44.1 12.3 27.7 20.3 19.8 15.6 33.6 9.5 10.1 33.4 21.6 14.6 23.9 10.3 9.8 10.0 12.5 19.9 10.4 15.0 10.7 17.4 46.8 15.8 16.7 13.5 58.6 16.4 36.3 17.3 10.6 14.5 20.0 4.8 9.8 35.3 24.8 37.1 22.7 17.6 12.8 11.1 54.8 15.4 31.8 23.0 20.0 27.7 0.1 26.2 29.0 22.1 25.5 0.2 24.2 12.4 13.7 19.8 32.7 12.6 21.9 72.0 46.1 247.5 14.0 97.6 12.5 17.4 43.3 29.8 22.4 30.6 25.8 20.6 42.0 18.9 32.2 41.0 5.5 86.2 54.3 12.0 32.1 33.6 20.6 44.5 8.9 20.1 15.6 39.6 50.6 11.4 25.1 32.7 26.0 40.6 50.6 22.5 32.8 41.4 23.1 28.0 34.8 24.7 51.7 16.4 25.3 25.6 48.6 18.6 16.1 244.3 18.8 38.3 43.0 25.5 54.0 48.9 53.7 56.7 27.6 42.9 51.1 51.2 22.8 52.7 17.9 44.3 74.9 44.0 9.6 10.5 10.3 13.8 9.5 10.1 10.3 9.8 10.7 10.6 9.8 11.1 27.8 12.8 25.5 25.5 22.0 26.4 23.4 144.2 27.3 11.8 56.9 58.7 58.7 22.8 49.7 22.0 0.0 88.6 23.1 139.2 109.5 82.5 0.8 39.6 28.1 21.2 26.5 25.2 18.8 51.1 108.7 25.3 20.9 22.0 90.7 14.6 15.0 27.5 82.8 10.1 26.7 124.2 83.4 21.7 35.6 1.9 16.4 33.0 33.8 21.5 84.3 24.4 24.7 20.1 40.5 82.7 157.2 19.9 23.0 27.3 191.3 76.8 52.6 15.1 0.0 26.0 33.2 21.2 13.7 41.1 30.3 65.8 33.0 23.1 106.1 24.0 PLSCR3 ENSG00000187838 "Phospholipid scramblase 3" Q9NRY6 17 7389727-7394842 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Alveolar cells type 2: 3.0;Ductal cells: 5.8;Exocrine glandular cells: 3.6;monocytes: 2.0;Pancreatic endocrine cells: 8.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048387, HPA068609" Supported Supported Mitochondria NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 72: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Mitochondria "HPA048387: AB_2680381, HPA068609: AB_2686011" "unprognostic (1.86e-2)" "unprognostic (5.29e-2)" "unprognostic (2.29e-2)" "unprognostic (1.56e-2)" "unprognostic (4.36e-2)" "unprognostic (5.02e-2)" "unprognostic (2.27e-2)" "unprognostic (9.71e-2)" "unprognostic (1.75e-3)" "unprognostic (1.91e-1)" "unprognostic (1.11e-2)" "unprognostic (1.77e-2)" "unprognostic (2.11e-5)" "unprognostic (1.24e-2)" "unprognostic (1.48e-1)" "unprognostic (1.97e-1)" "unprognostic (2.55e-2)" 39.5 21.1 7.4 11.0 7.5 3.3 35.0 7.0 8.5 46.2 7.2 27.1 3.1 44.5 5.9 37.4 29.4 6.5 32.0 6.8 7.4 23.5 14.4 32.8 10.5 8.5 7.3 30.5 16.7 5.6 16.4 7.0 7.6 24.7 3.4 1.2 22.9 8.0 21.2 35.2 21.9 12.3 7.4 40.7 21.9 6.1 8.1 6.4 22.8 11.1 10.5 34.8 38.1 7.7 26.7 6.6 5.7 17.2 19.4 32.8 6.8 24.1 22.1 21.3 19.3 9.8 6.6 7.3 19.4 35.1 9.0 37.6 7.0 41.4 10.9 19.0 4.0 6.7 9.2 6.0 23.6 2.5 8.2 22.6 25.4 20.7 30.1 32.0 32.3 14.5 4.1 5.6 27.1 14.3 7.7 2.0 5.1 7.1 18.3 15.1 4.3 8.3 20.1 17.7 4.7 15.6 13.9 8.8 5.9 5.0 16.0 1.3 53.2 13.9 14.5 15.7 10.3 6.2 7.4 3.0 22.4 8.4 15.9 7.0 24.5 2.8 39.5 34.1 40.8 32.2 72.8 40.7 24.1 32.5 59.2 36.1 2.6 18.0 30.2 2.8 83.5 33.3 7.4 7.5 7.0 8.5 6.8 7.4 8.5 7.3 7.6 7.4 8.1 7.7 1.0 3.2 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 5.8 0.0 0.1 1.0 1.0 0.0 0.0 0.0 3.6 0.3 1.0 0.0 0.1 1.3 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.3 0.6 0.1 0.0 0.0 PLXNC1 "CD232, VESPR" ENSG00000136040 "Plexin C1" O60486 12 94148577-94307675 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 57.0;Macrophages: 62.5;Melanocytes: 96.0;monocytes: 53.8" "Cancer enhanced" "Detected in all" "melanoma: 24.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 16.4" "Group enriched" "Detected in all" 4 "granulocytes: 16.4;monocytes: 8.6" "Cell line enhanced" "Detected in many" "HAP1: 33.3;Karpas-707: 25.8;SK-MEL-30: 41.4;U-266/70: 64.3;U-266/84: 73.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066899 Approved Mitochondria NA NA 150000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Mitochondria "HPA066899: AB_2685743" "unprognostic (1.49e-1)" "unprognostic (4.01e-2)" "unprognostic (5.60e-2)" "unprognostic (1.99e-1)" "unprognostic (2.33e-1)" "unprognostic (3.24e-2)" "unprognostic (4.67e-3)" "unprognostic (2.80e-2)" "unprognostic (3.49e-1)" "unprognostic (4.64e-2)" "unprognostic (1.78e-2)" "unprognostic (2.38e-1)" "unprognostic (4.02e-2)" "unprognostic (5.33e-3)" "unprognostic (3.19e-2)" "unprognostic (6.85e-3)" "unprognostic (5.48e-2)" 6.1 8.8 6.4 20.5 7.1 17.4 4.7 8.9 7.5 8.5 1.9 5.7 4.1 7.0 2.7 3.8 4.8 10.2 1.9 7.1 15.9 4.0 2.5 11.4 16.2 5.3 12.7 14.8 2.4 0.9 4.1 9.4 4.7 2.3 6.5 2.2 2.3 4.5 4.0 8.3 5.5 6.9 4.2 19.8 4.5 15.2 18.6 5.7 3.4 4.1 13.0 9.5 3.8 8.7 1.1 0.4 2.7 0.5 1.5 1.2 0.4 1.3 1.8 1.7 5.1 9.1 0.1 21.8 0.1 2.0 1.6 0.1 33.3 1.4 1.2 15.3 0.7 1.2 0.6 6.1 17.7 4.5 7.2 17.7 0.0 1.9 0.8 2.3 0.0 2.0 0.6 25.8 0.5 0.3 1.0 2.4 5.5 0.2 1.2 3.6 1.0 12.1 0.1 1.7 2.2 1.6 0.3 0.2 41.4 6.3 0.1 3.7 0.7 0.6 2.3 0.2 0.8 64.3 73.3 1.4 0.4 11.7 1.4 0.0 3.6 15.1 1.6 6.1 1.7 2.6 1.7 1.9 2.9 1.7 1.6 1.6 16.4 1.1 8.6 1.1 1.3 2.0 6.4 7.1 8.9 7.5 7.1 15.9 5.3 12.7 4.7 4.2 18.6 8.7 4.9 3.2 2.4 9.8 17.9 6.1 0.3 0.3 1.2 3.6 3.2 2.5 8.1 1.5 0.2 0.0 0.0 0.2 5.6 1.2 1.9 0.2 9.4 3.2 14.9 4.3 19.8 26.1 36.1 0.5 0.2 16.0 1.1 1.6 16.5 29.8 6.1 1.6 18.8 0.0 57.0 1.8 0.0 39.4 13.8 6.2 1.5 62.5 96.0 40.3 53.8 0.3 3.1 34.2 12.6 0.3 1.8 3.4 24.4 0.2 0.1 3.4 2.3 0.5 6.6 2.8 2.5 3.0 1.1 0.7 1.6 0.1 9.4 4.8 1.9 0.3 PMPCA "Alpha-MPP, CLA1, INPP5E, KIAA0123, SCAR2" ENSG00000165688 "Peptidase, mitochondrial processing subunit alpha" Q10713 9 136410641-136423761 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Disease variant, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021648, HPA063735" Supported Enhanced Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA021648: AB_1855491, HPA063735: AB_2685108" "unprognostic (9.80e-2)" "unprognostic (1.96e-2)" "unprognostic (4.03e-1)" "unprognostic (1.69e-2)" "unprognostic (4.01e-2)" "unprognostic (8.19e-2)" "unprognostic (6.09e-2)" "unprognostic (1.19e-2)" "unprognostic (1.97e-1)" "unprognostic (3.32e-2)" "prognostic favorable (8.00e-5)" "unprognostic (9.47e-3)" "prognostic favorable (2.14e-6)" "unprognostic (4.27e-3)" "unprognostic (1.57e-2)" "unprognostic (2.40e-1)" "unprognostic (3.54e-2)" 29.2 58.1 27.0 20.6 27.6 31.4 27.1 27.0 34.6 29.2 36.8 32.2 24.8 26.8 10.4 34.5 27.5 17.9 73.2 28.0 27.3 37.3 110.8 25.4 27.1 27.1 27.6 29.3 28.8 26.9 38.8 20.8 27.9 31.8 15.3 8.8 28.4 16.1 69.2 37.6 30.6 15.3 25.6 38.2 35.3 37.8 27.9 21.4 29.4 50.0 17.0 28.0 27.8 26.7 48.7 87.7 41.8 84.5 30.8 45.0 63.2 49.3 39.6 67.2 48.9 101.1 56.5 67.4 50.5 50.3 36.2 110.2 77.9 72.0 30.0 97.2 92.8 54.6 113.2 123.6 53.9 71.7 44.9 66.3 48.9 52.6 27.0 38.2 58.0 61.2 140.2 43.4 42.6 132.1 68.1 90.1 85.4 86.2 82.2 83.0 59.1 149.9 46.3 33.9 85.4 56.1 66.6 92.9 58.6 28.6 127.6 95.5 48.2 47.8 50.7 39.8 63.8 26.2 37.4 73.5 62.9 61.3 43.9 37.4 50.5 36.5 53.2 51.9 51.4 52.5 49.0 57.2 61.7 48.8 57.9 50.2 11.9 67.2 51.5 31.4 52.7 62.2 27.0 27.6 27.0 34.6 28.0 27.3 27.1 27.6 27.9 25.6 27.9 26.7 17.3 16.0 26.7 14.7 24.2 27.5 40.2 65.0 27.9 24.7 19.3 15.2 35.9 15.7 32.8 22.0 22.9 103.1 22.5 28.0 49.0 32.9 24.6 25.6 23.5 21.7 20.8 23.5 13.8 30.7 50.4 23.7 21.9 26.2 24.7 44.2 19.6 57.2 37.8 18.5 11.4 24.2 44.7 19.2 14.6 15.8 19.0 17.4 16.0 6.5 21.0 22.9 14.4 8.5 8.0 31.6 20.9 22.6 26.6 22.6 25.6 46.9 22.6 27.4 39.5 22.4 27.9 37.7 42.4 23.2 26.9 103.8 21.7 77.0 38.6 28.5 PMPCB "MPPB, MPPP52" ENSG00000105819 "Peptidase, mitochondrial processing subunit beta" O75439 7 103297435-103329511 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040674, HPA074168" Approved Enhanced Mitochondria No No 19000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA040674: AB_10961998, HPA074168: AB_2686671" "prognostic favorable (2.79e-4)" "unprognostic (3.11e-1)" "unprognostic (7.18e-3)" "unprognostic (3.03e-1)" "unprognostic (3.65e-2)" "unprognostic (1.72e-1)" "unprognostic (1.06e-1)" "unprognostic (7.67e-2)" "unprognostic (7.74e-2)" "unprognostic (1.21e-1)" "unprognostic (1.38e-1)" "unprognostic (1.42e-3)" "prognostic favorable (2.95e-8)" "unprognostic (2.59e-2)" "unprognostic (9.79e-2)" "unprognostic (2.40e-1)" "unprognostic (4.39e-2)" 30.8 42.0 16.9 22.3 18.2 53.5 32.5 18.9 22.1 33.3 24.7 33.4 38.0 29.9 26.2 27.7 29.3 25.1 44.9 18.8 18.1 47.4 46.1 22.6 36.4 16.5 16.6 35.4 41.1 39.7 22.4 25.8 17.6 31.5 33.2 25.4 30.6 28.1 34.8 33.2 32.4 26.3 17.2 28.2 35.8 26.7 17.4 30.2 33.4 38.2 33.9 29.3 28.4 19.9 30.2 42.8 49.9 69.4 28.5 57.1 38.0 26.7 45.6 54.3 62.8 47.7 33.7 76.9 41.7 47.9 58.0 37.5 59.7 43.2 49.2 26.4 69.4 26.4 74.0 61.6 35.0 35.0 30.6 53.4 40.5 41.8 39.6 51.3 28.8 55.9 52.5 77.9 48.5 71.1 59.2 82.0 59.2 60.4 52.4 42.7 34.3 79.4 50.3 54.2 62.2 76.5 37.3 108.6 55.8 49.5 45.3 49.1 24.9 48.3 57.9 85.1 52.3 57.4 79.9 61.8 35.7 59.3 38.2 16.7 19.3 13.2 18.3 21.4 20.1 25.9 21.1 18.5 24.7 19.3 26.1 21.7 5.7 17.9 19.7 12.6 30.2 22.3 16.9 18.2 18.9 22.1 18.8 18.1 16.5 16.6 17.6 17.2 17.4 19.9 32.0 32.1 36.9 27.1 54.5 36.7 68.2 123.2 51.8 31.6 41.3 37.3 70.4 41.5 70.7 27.6 22.9 125.6 55.9 35.8 72.4 75.6 106.3 38.4 37.0 37.1 27.1 65.8 36.8 73.2 61.3 42.5 35.7 35.0 60.2 49.9 31.1 53.7 54.6 23.5 33.9 48.1 75.3 49.4 30.7 24.0 51.9 42.4 26.6 18.7 92.5 35.8 58.7 35.7 44.4 59.7 45.4 49.7 56.1 35.2 60.4 127.5 58.2 37.9 65.7 48.6 73.5 125.4 56.4 47.1 37.5 124.9 55.9 63.3 59.1 62.2 PNKD "BRP17, DKFZp564N1362, DYT8, FKSG19, FPD1, KIAA1184, KIPP1184, MGC31943, MR-1, MR-1S, PDC, PKND1, TAHCCP2" ENSG00000127838 "PNKD metallo-beta-lactamase domain containing" Q8N490 2 218270392-218346793 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 508.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010134, HPA017068" Approved Enhanced Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA010134: AB_1079645, HPA017068: AB_1855495" "unprognostic (3.15e-3)" "unprognostic (1.80e-2)" "unprognostic (5.86e-3)" "unprognostic (1.89e-2)" "unprognostic (1.90e-1)" "unprognostic (1.60e-1)" "unprognostic (3.81e-2)" "unprognostic (1.54e-1)" "unprognostic (1.37e-1)" "unprognostic (7.51e-2)" "unprognostic (3.29e-1)" "unprognostic (7.67e-2)" "prognostic unfavorable (5.13e-5)" "unprognostic (7.98e-2)" "unprognostic (2.17e-1)" "unprognostic (9.61e-2)" "unprognostic (1.44e-3)" 50.9 88.9 127.6 33.3 134.7 35.4 49.7 131.2 168.4 62.8 129.3 74.7 40.6 45.6 77.3 40.5 60.6 41.6 98.4 127.8 137.5 106.5 191.5 55.5 40.9 133.9 130.9 47.1 46.1 93.4 49.5 46.9 134.1 87.4 54.7 26.7 60.6 55.3 85.1 44.9 51.1 36.4 128.7 58.7 81.6 45.6 137.8 45.8 90.0 93.6 37.6 64.2 45.4 134.7 53.2 68.3 49.1 77.0 72.2 60.6 90.0 32.7 70.3 76.1 85.0 112.9 51.2 61.7 63.7 55.0 83.5 53.6 95.4 61.4 52.9 128.0 119.4 90.0 119.5 169.4 78.7 58.9 38.6 83.0 59.8 51.9 15.0 51.0 83.2 48.0 67.8 78.3 68.4 152.2 77.6 139.5 49.0 121.3 69.3 75.1 49.5 51.8 88.3 79.2 47.4 39.9 23.6 156.9 94.6 52.0 52.4 56.4 51.5 31.4 53.7 37.5 45.5 32.4 35.7 69.0 79.9 95.8 38.8 142.4 111.4 151.9 97.7 114.3 94.2 223.1 105.7 117.7 106.4 187.2 116.4 111.2 31.3 136.2 109.4 99.0 150.0 132.2 127.6 134.7 131.2 168.4 127.8 137.5 133.9 130.9 134.1 128.7 137.8 134.7 84.5 70.5 91.2 30.0 58.2 55.2 91.5 179.2 82.6 54.5 130.1 162.4 154.5 128.7 127.8 196.8 6.2 172.9 48.2 292.0 508.7 70.6 13.5 125.9 116.5 66.9 121.3 56.3 44.9 49.8 105.3 88.5 99.9 114.1 57.1 97.0 83.2 250.4 136.7 35.3 47.4 186.3 187.2 85.3 59.6 16.5 103.2 66.2 136.9 20.6 79.6 168.8 51.5 19.6 32.8 37.7 143.6 124.1 74.6 93.4 162.7 326.7 148.5 41.6 92.1 60.0 128.6 42.5 50.6 113.9 62.4 77.3 52.5 97.2 228.1 117.5 POLDIP2 "DKFZP586F1524, PDIP38" ENSG00000004142 "DNA polymerase delta interacting protein 2" Q9Y2S7 17 28346633-28357527 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 189.8;Proximal tubular cells: 203.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CACO-2: 544.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007700 Approved Mitochondria NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA007700: AB_2667900" "unprognostic (5.71e-2)" "unprognostic (4.04e-1)" "unprognostic (2.03e-2)" "unprognostic (2.07e-2)" "unprognostic (3.23e-1)" "unprognostic (5.99e-2)" "unprognostic (1.14e-1)" "unprognostic (1.11e-1)" "unprognostic (2.46e-1)" "unprognostic (1.24e-1)" "unprognostic (2.98e-1)" "unprognostic (1.62e-1)" "unprognostic (3.04e-3)" "unprognostic (1.57e-1)" "unprognostic (2.13e-1)" "unprognostic (8.40e-2)" "unprognostic (4.39e-2)" 50.0 130.2 52.5 35.4 53.6 45.9 48.0 53.7 55.8 40.2 53.7 53.0 45.5 43.1 44.1 76.0 39.6 30.1 142.1 54.3 56.1 101.6 188.4 36.4 34.4 53.8 54.7 41.1 79.0 66.0 44.3 31.1 52.4 47.5 56.9 30.1 52.7 44.6 273.1 58.2 42.1 53.0 51.5 43.8 63.0 58.4 56.5 50.2 43.3 210.3 50.6 49.8 43.4 51.9 99.4 169.9 65.5 101.1 95.3 95.0 77.6 102.0 107.2 213.2 149.0 544.8 56.7 174.5 94.7 134.0 111.2 127.2 153.1 111.0 162.0 138.9 136.4 63.4 97.0 115.0 152.0 141.5 75.7 106.0 160.4 148.4 124.9 96.1 118.9 123.8 140.8 101.3 130.0 126.8 163.6 73.9 74.8 166.2 75.9 116.8 139.4 172.8 113.0 89.2 88.6 84.3 181.2 357.6 101.8 102.7 189.6 97.6 102.5 94.4 71.2 110.1 179.4 89.0 115.0 125.6 134.4 93.8 95.7 41.6 48.5 42.6 33.5 47.1 33.5 49.0 35.3 43.8 60.1 31.1 37.5 37.1 19.4 33.8 35.0 40.3 42.5 52.6 52.5 53.6 53.7 55.8 54.3 56.1 53.8 54.7 52.4 51.5 56.5 51.9 20.4 9.6 18.1 13.1 27.7 27.5 32.5 61.6 33.0 24.5 43.1 35.2 96.7 62.9 31.5 47.8 4.2 82.0 17.0 55.9 189.8 102.0 44.9 15.5 22.3 29.1 23.4 54.3 12.7 143.2 97.0 29.5 34.7 20.5 11.4 46.8 22.9 125.1 69.6 28.6 13.1 42.4 32.6 36.5 25.7 132.4 30.7 25.6 58.7 5.6 51.9 39.6 36.0 9.0 8.9 112.7 37.6 33.1 46.1 46.7 74.5 203.6 13.5 18.4 13.1 22.0 47.0 64.3 45.0 55.2 30.1 81.3 22.5 66.1 66.3 38.8 POLG "POLG1, POLGA" ENSG00000140521 "DNA polymerase gamma, catalytic subunit" P54098 15 89305198-89334861 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA replication" "DNA-binding, DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Disease variant, Epilepsy, Leigh syndrome, Neurodegeneration, Neuropathy, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056821, HPA078482" Approved Supported Mitochondria NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 65: Plasmacytoid DCs - Unknown function" Mitochondria "HPA056821: AB_2683247, HPA078482: " "unprognostic (1.87e-1)" "unprognostic (4.71e-2)" "unprognostic (2.61e-2)" "unprognostic (3.64e-1)" "unprognostic (1.62e-1)" "unprognostic (3.19e-1)" "unprognostic (2.22e-1)" "unprognostic (1.13e-1)" "unprognostic (8.41e-2)" "unprognostic (2.63e-1)" "unprognostic (1.41e-1)" "prognostic unfavorable (5.73e-4)" "unprognostic (2.65e-3)" "unprognostic (1.58e-2)" "unprognostic (4.29e-2)" "unprognostic (2.07e-1)" "unprognostic (3.45e-1)" 13.3 11.1 6.8 4.0 5.0 2.6 12.0 4.8 6.3 12.0 4.5 13.3 5.5 12.9 0.4 14.6 11.2 0.9 13.8 6.1 3.5 10.1 12.9 13.8 3.0 9.0 5.8 10.8 10.7 2.9 8.4 2.5 6.5 10.5 0.9 1.4 12.3 2.2 25.0 16.0 14.5 1.3 5.4 16.2 11.9 5.4 5.7 7.3 10.5 10.9 2.4 12.2 12.7 6.3 8.0 17.0 6.7 10.0 7.7 1.6 16.4 16.4 2.7 7.9 5.9 28.0 10.9 14.4 33.6 5.9 16.9 11.8 14.3 4.8 0.9 35.8 31.3 19.4 19.5 11.1 10.8 21.3 33.6 2.4 8.7 7.0 3.0 8.3 12.2 26.8 19.5 5.4 6.1 22.8 16.3 16.5 8.7 13.7 8.2 18.2 13.7 17.4 3.2 19.2 24.5 6.9 26.8 9.6 16.8 6.0 7.7 10.8 17.3 12.8 15.6 28.5 14.2 17.0 9.4 18.6 9.5 14.3 11.6 3.3 4.3 6.1 5.5 4.0 4.3 2.0 4.6 6.8 6.0 3.0 3.7 4.4 1.8 5.0 3.5 4.1 3.3 5.3 6.8 5.0 4.8 6.3 6.1 3.5 9.0 5.8 6.5 5.4 5.7 6.3 15.7 12.8 11.9 11.4 17.2 12.2 11.0 10.7 9.1 7.6 12.0 10.3 19.0 11.5 9.5 11.0 2.1 15.0 33.8 17.2 9.8 10.4 1.3 8.4 9.4 12.4 5.4 9.0 12.9 10.9 15.8 11.9 21.4 11.3 8.2 14.8 14.6 17.8 12.7 3.3 9.9 24.9 4.1 18.5 14.7 1.5 14.3 17.2 19.6 8.4 21.8 6.1 30.9 9.5 11.9 11.4 15.9 10.5 16.8 17.7 10.5 7.5 7.8 6.4 6.6 13.3 12.9 9.2 11.1 11.8 11.9 21.8 21.7 14.8 17.6 15.5 POLRMT "APOLMT, h-mtRPOL, MTRNAP, MTRPOL" ENSG00000099821 "RNA polymerase mitochondrial" O00411 19 617221-633537 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transcription "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 84.0;Spermatogonia: 84.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006366 Uncertain Supported Mitochondria NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 21: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Mitochondria "HPA006366: AB_1079654" "unprognostic (3.24e-1)" "unprognostic (4.31e-2)" "unprognostic (7.96e-2)" "prognostic favorable (4.50e-4)" "unprognostic (9.46e-2)" "unprognostic (2.94e-2)" "unprognostic (3.04e-2)" "unprognostic (9.41e-2)" "unprognostic (1.45e-1)" "unprognostic (3.48e-1)" "unprognostic (7.64e-3)" "unprognostic (1.81e-2)" "unprognostic (1.62e-1)" "unprognostic (1.28e-3)" "unprognostic (1.66e-1)" "unprognostic (2.92e-1)" "unprognostic (1.01e-1)" 17.2 23.9 19.5 9.1 20.5 6.8 18.1 20.7 28.5 19.3 16.9 22.3 14.5 19.7 10.0 21.0 19.2 5.3 38.0 20.1 17.5 26.2 41.3 16.0 9.6 24.4 20.4 20.7 26.3 11.4 22.7 5.0 21.3 20.7 7.2 5.7 17.2 9.2 69.2 27.9 23.9 6.6 17.8 22.5 21.8 66.6 20.9 11.0 20.1 14.9 7.5 21.5 17.7 24.4 24.5 43.6 9.7 42.1 19.7 11.0 35.7 11.1 12.9 15.7 14.5 44.2 15.9 24.9 22.0 10.2 7.9 24.5 35.5 21.0 11.8 28.3 86.8 19.3 26.4 56.9 20.5 32.6 34.7 10.7 29.3 16.4 19.7 11.3 22.9 34.0 37.3 23.6 14.8 34.3 43.7 44.7 38.4 31.1 30.2 42.0 13.3 42.4 21.4 20.7 30.7 22.1 10.2 26.7 28.4 10.3 15.4 29.9 14.1 17.2 22.0 26.9 33.3 57.4 51.0 38.7 36.9 27.3 21.8 0.0 2.9 2.5 6.2 3.8 5.0 5.6 4.6 4.6 5.5 6.3 3.9 4.5 0.5 6.0 4.2 5.4 3.1 4.6 19.5 20.5 20.7 28.5 20.1 17.5 24.4 20.4 21.3 17.8 20.9 24.4 10.3 12.8 11.5 2.6 14.2 8.0 6.1 5.8 10.2 18.3 9.1 8.0 18.0 15.7 7.9 16.5 18.8 15.5 13.3 31.5 7.9 6.7 39.8 7.7 6.1 9.7 13.1 9.4 2.7 8.0 8.7 8.9 14.3 8.6 12.7 15.1 8.2 21.9 10.4 11.8 2.7 12.7 4.1 8.3 7.4 84.0 12.5 8.0 10.6 3.7 7.4 8.4 18.6 1.5 4.6 6.5 12.4 13.2 7.8 10.3 26.0 15.1 6.4 18.1 6.6 8.9 10.0 31.6 84.9 10.6 7.2 7.7 12.7 15.6 24.4 6.2 PPA2 FLJ20459 ENSG00000138777 "Inorganic pyrophosphatase 2" Q9H2U2 4 105369077-105474067 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030888, HPA031671, HPA031672" Supported Approved Mitochondria NA NA 150000 "Cluster 44: Non-specific - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA030888: AB_2673646, HPA031671: AB_10603986, HPA031672: AB_2673988" "prognostic unfavorable (2.98e-4)" "unprognostic (5.64e-2)" "prognostic favorable (6.60e-4)" "unprognostic (9.26e-3)" "unprognostic (2.93e-2)" "unprognostic (5.10e-2)" "unprognostic (1.15e-1)" "unprognostic (2.44e-1)" "unprognostic (1.50e-1)" "unprognostic (1.20e-1)" "unprognostic (7.05e-2)" "unprognostic (9.54e-2)" "prognostic favorable (1.27e-11)" "unprognostic (3.69e-1)" "unprognostic (1.94e-1)" "unprognostic (2.00e-1)" "unprognostic (1.10e-1)" 7.4 12.8 23.8 9.0 24.6 22.0 12.0 24.3 53.7 7.4 29.5 17.4 14.2 7.4 12.5 10.8 8.4 8.0 27.5 23.7 26.3 20.7 14.8 7.5 8.3 24.4 24.3 5.8 11.8 11.7 7.7 7.4 24.5 13.3 14.0 13.6 13.8 5.7 27.6 12.2 13.8 6.8 24.0 9.9 12.6 6.3 25.4 7.0 11.5 35.5 8.7 8.1 6.7 26.6 20.6 8.5 18.5 32.3 11.3 9.1 12.9 10.2 15.7 14.6 9.9 22.2 30.4 15.6 14.5 9.7 11.3 9.5 39.2 18.7 17.0 23.6 11.8 13.5 13.7 19.9 9.3 36.7 13.6 9.7 19.6 9.9 7.9 15.4 14.6 28.4 22.3 22.0 12.5 26.2 32.5 26.6 13.9 42.4 28.3 28.2 10.9 17.9 49.7 14.7 17.8 10.7 7.8 48.9 19.0 10.7 24.8 32.1 6.9 9.2 19.2 8.9 20.0 19.0 27.3 18.4 17.5 18.6 14.1 27.0 20.9 15.4 21.0 30.1 18.6 28.5 21.7 23.7 49.9 22.6 21.1 23.9 9.5 36.4 26.4 25.9 23.4 23.5 23.8 24.6 24.3 53.7 23.7 26.3 24.4 24.3 24.5 24.0 25.4 26.6 26.7 9.6 67.3 86.2 37.6 50.0 82.4 205.0 38.1 29.7 64.8 40.9 63.3 45.8 126.2 33.1 16.7 119.0 25.9 73.3 264.1 114.0 113.7 42.3 35.3 36.3 65.7 70.2 138.2 120.1 98.5 31.1 37.2 42.3 45.6 26.4 24.3 64.2 83.5 21.9 134.6 104.6 142.4 42.9 86.1 126.4 27.7 47.1 76.5 74.9 50.5 39.2 30.9 169.9 145.7 65.0 90.4 32.4 41.9 68.1 112.2 285.4 90.7 22.6 39.5 46.3 43.6 50.8 10.8 59.1 57.7 84.7 34.3 72.1 138.0 94.6 PPCS FLJ11838 ENSG00000127125 "Phosphopantothenoylcysteine synthetase" Q9HAB8 1 42456117-42473385 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 397.2;Proximal tubular cells: 316.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031361, HPA031363" Approved Approved Mitochondria NA NA 17000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA031361: AB_10602150, HPA031363: AB_2673844" "unprognostic (1.49e-1)" "unprognostic (6.71e-2)" "unprognostic (8.15e-2)" "unprognostic (1.55e-1)" "unprognostic (3.84e-3)" "unprognostic (1.68e-2)" "prognostic unfavorable (5.96e-5)" "unprognostic (2.71e-1)" "unprognostic (7.79e-3)" "unprognostic (9.13e-3)" "unprognostic (3.24e-2)" "unprognostic (2.44e-1)" "unprognostic (2.41e-2)" "unprognostic (6.45e-2)" "unprognostic (2.32e-1)" "unprognostic (2.80e-1)" "unprognostic (4.30e-2)" 51.0 62.7 28.2 34.6 29.3 27.1 65.0 29.8 34.6 44.2 36.8 63.5 58.0 35.8 71.0 48.4 31.7 43.1 42.5 28.6 32.0 88.1 99.6 39.8 43.5 30.1 28.8 30.2 66.9 59.8 27.8 38.0 29.1 52.3 58.0 22.4 59.3 44.2 45.9 47.0 56.4 29.0 31.6 42.2 64.7 15.0 29.9 27.8 64.8 40.4 38.2 43.3 40.1 32.9 83.4 34.3 17.2 28.8 52.3 55.0 72.1 40.7 43.3 49.1 44.2 30.7 93.3 22.6 80.7 46.2 30.3 48.8 11.5 62.5 40.3 66.2 35.1 39.9 34.7 31.3 72.5 39.9 69.4 48.8 98.9 35.8 62.4 58.2 48.3 29.9 16.9 17.0 50.5 47.3 20.4 40.1 22.6 70.0 49.8 22.6 18.8 45.3 106.2 70.7 23.0 25.0 47.9 113.2 129.4 50.2 56.7 167.8 31.1 28.2 41.1 42.9 46.5 58.6 37.3 17.5 12.6 44.4 61.0 298.8 231.5 325.6 114.5 245.4 135.2 171.5 141.1 128.0 195.9 182.4 149.5 132.9 159.5 185.6 237.2 135.8 160.9 262.8 28.2 29.3 29.8 34.6 28.6 32.0 30.1 28.8 29.1 31.6 29.9 32.9 61.0 57.7 84.1 5.9 62.6 23.3 42.3 99.4 42.7 12.1 91.3 100.2 104.3 84.4 90.8 64.4 6.2 172.2 52.6 129.2 397.2 96.5 3.5 66.7 43.9 48.7 31.3 29.0 7.4 136.8 131.0 52.9 61.7 59.3 57.0 52.8 44.6 120.1 107.4 11.8 7.0 124.9 103.7 84.4 44.3 4.6 60.6 76.3 81.8 6.5 127.0 64.8 79.3 8.0 8.7 98.5 125.2 63.6 41.8 51.7 159.7 316.3 63.2 28.0 26.3 26.2 48.9 10.3 20.8 66.3 36.2 134.6 62.5 103.2 101.2 60.1 PPFIBP2 Cclp1 ENSG00000166387 "PPFIA binding protein 2" Q8ND30 11 7513298-7657127 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 53.4;Extravillous trophoblasts: 56.2;Oligodendrocytes: 70.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 80.5;OE19: 100.4;RT4: 105.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001935, HPA003911" Enhanced Approved Mitochondria NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 21: OE19 - Mitochondria" "Cluster 44: Endometrium - Transcription" Mitochondria "HPA001935: AB_1079667, HPA003911: AB_1079666" "unprognostic (4.14e-2)" "unprognostic (7.04e-3)" "unprognostic (7.20e-3)" "unprognostic (5.79e-2)" "unprognostic (2.08e-1)" "prognostic favorable (2.32e-4)" "unprognostic (1.33e-1)" "prognostic favorable (2.26e-5)" "unprognostic (6.66e-3)" "unprognostic (2.90e-1)" "unprognostic (1.85e-1)" "unprognostic (1.17e-1)" "prognostic favorable (5.39e-8)" "unprognostic (1.78e-1)" "unprognostic (3.38e-1)" "unprognostic (2.52e-2)" "prognostic favorable (1.34e-5)" 10.8 11.7 21.5 12.0 34.2 7.6 16.6 24.9 24.4 14.7 51.3 22.4 26.4 6.7 33.5 27.3 17.2 15.7 13.0 21.8 26.2 19.0 35.4 11.6 15.2 27.4 29.8 14.3 9.4 66.5 4.8 21.0 29.0 18.2 26.5 2.8 54.8 32.8 33.4 33.2 26.0 5.4 20.6 11.1 44.1 31.5 31.7 4.5 37.5 21.4 25.0 29.5 21.8 43.8 2.0 32.7 5.3 3.1 6.1 0.4 80.5 7.1 16.1 4.1 4.0 26.7 4.6 9.7 3.7 4.1 15.1 14.2 21.0 2.1 3.7 3.9 2.4 0.0 0.3 17.1 8.4 19.6 9.3 10.7 7.6 0.0 4.5 0.4 1.5 2.0 0.9 26.5 4.0 15.9 0.0 19.0 37.8 100.4 0.1 3.3 0.1 17.4 0.1 105.0 1.5 12.4 1.1 28.9 21.9 14.6 4.0 14.7 0.5 1.9 2.8 6.4 0.7 14.1 11.1 8.3 2.3 4.5 13.0 3.4 9.1 6.5 3.1 11.2 2.3 12.7 5.0 2.1 8.3 7.2 6.6 5.2 4.2 2.6 14.4 0.6 1.1 5.2 21.5 34.2 24.9 24.4 21.8 26.2 27.4 29.8 29.0 20.6 31.7 43.8 1.7 16.0 13.6 3.9 21.2 5.5 18.7 4.5 10.2 1.5 10.1 7.7 5.2 11.5 13.7 14.7 18.8 9.1 1.6 29.8 9.8 5.8 53.4 6.7 4.8 3.2 3.6 0.0 3.8 9.6 56.2 7.7 40.2 35.7 7.0 0.6 1.1 17.3 7.1 0.0 6.0 23.2 8.2 10.4 7.2 47.2 4.7 11.3 16.0 17.8 15.7 1.7 3.1 49.8 70.5 6.9 22.8 7.2 9.0 13.4 26.8 19.7 7.5 3.3 0.0 5.7 10.2 22.2 2.6 10.7 9.9 4.8 2.0 1.2 18.0 18.6 PPIF "Cyp-D, hCyP3" ENSG00000108179 "Peptidylprolyl isomerase F" P30405 10 79347469-79355334 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Necrosis" "Isomerase, Rotamase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 370.9;Macrophages: 160.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 75.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077416 Supported Mitochondria NA NA 320000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 1: K-562 - Erythropoiesis" "Cluster 41: Macrophages - Immune response" Mitochondria "HPA077416: AB_2686840" "unprognostic (2.21e-1)" "unprognostic (5.48e-2)" "unprognostic (1.68e-1)" "unprognostic (1.72e-3)" "unprognostic (1.69e-1)" "unprognostic (3.16e-3)" "unprognostic (3.45e-1)" "unprognostic (4.33e-3)" "unprognostic (1.66e-1)" "unprognostic (1.97e-1)" "unprognostic (2.82e-1)" "unprognostic (9.37e-3)" "unprognostic (1.02e-3)" "unprognostic (1.23e-1)" "unprognostic (1.66e-1)" "unprognostic (1.69e-3)" "unprognostic (4.88e-2)" 62.7 227.7 42.7 42.8 48.4 168.8 42.4 57.9 69.6 27.6 63.7 50.0 36.3 14.0 7.2 66.0 22.9 19.5 119.1 38.1 45.2 63.3 174.9 29.1 32.3 49.0 56.2 19.3 86.9 77.6 18.3 27.1 48.8 18.8 52.4 8.9 39.5 45.5 99.5 71.9 31.3 21.0 50.6 58.7 98.2 35.0 57.1 28.3 26.0 133.6 55.5 60.0 35.1 60.8 220.4 90.6 62.3 123.5 57.0 73.6 79.8 124.2 161.2 265.7 249.6 213.5 102.7 224.8 68.0 87.4 188.6 127.8 195.3 115.4 410.5 72.2 186.4 352.8 87.5 380.7 96.4 245.7 80.4 173.2 81.3 264.5 262.3 86.5 47.5 86.4 351.6 268.3 91.6 111.7 64.1 204.2 53.0 99.6 500.6 109.8 96.4 114.7 103.9 200.0 124.1 92.0 63.6 253.8 97.9 40.5 111.4 187.2 43.5 116.1 106.3 137.9 242.0 124.7 137.7 181.9 114.5 313.9 32.0 15.2 34.3 18.0 10.4 27.5 10.9 19.1 9.1 9.6 43.3 7.7 8.1 7.9 75.0 9.0 10.4 5.4 10.0 16.6 42.7 48.4 57.9 69.6 38.1 45.2 49.0 56.2 48.8 50.6 57.1 60.8 8.4 6.4 6.8 7.2 32.7 42.6 30.2 23.8 31.3 4.0 41.8 40.8 124.6 14.3 14.4 12.9 6.2 99.4 26.4 39.9 92.0 42.1 14.5 12.4 24.0 10.1 21.6 37.0 4.1 28.0 127.1 25.1 78.0 15.5 13.4 73.4 6.1 98.5 91.1 8.4 5.7 69.5 18.3 40.3 370.9 14.1 6.2 160.8 35.6 4.7 32.0 13.0 5.2 5.5 15.0 39.8 26.6 6.0 48.7 41.4 21.3 41.2 12.6 5.2 19.7 18.2 28.6 14.8 22.5 52.9 37.6 142.3 23.9 60.2 81.1 34.2 PPM1K "BDP, DKFZp761G058, hPTMP, PP2Ckappa, PP2Cm" ENSG00000163644 "Protein phosphatase, Mg2+/Mn2+ dependent 1K" Q8N3J5 4 88257620-88284769 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 92.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 512.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 58.0;Karpas-707: 48.6;U-698: 48.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020066, HPA020862, HPA023891" Approved Supported Mitochondria No No "Cluster 24: B-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA020066: AB_1855628, HPA020862: AB_1855629, HPA023891: AB_1855630" "unprognostic (2.38e-2)" "unprognostic (5.86e-2)" "unprognostic (7.42e-3)" "unprognostic (6.70e-3)" "unprognostic (1.18e-1)" "unprognostic (1.17e-3)" "unprognostic (1.87e-1)" "unprognostic (5.88e-2)" "unprognostic (5.50e-2)" "unprognostic (1.41e-2)" "unprognostic (9.25e-3)" "unprognostic (6.56e-2)" "unprognostic (9.82e-2)" "unprognostic (5.57e-2)" "unprognostic (1.34e-1)" "unprognostic (2.11e-1)" "unprognostic (2.28e-1)" 5.3 8.5 23.3 14.9 26.3 9.9 14.5 22.5 31.2 19.4 22.0 5.9 4.4 32.7 7.6 11.2 21.5 8.9 92.5 26.5 23.9 17.8 7.6 9.7 25.6 19.9 22.3 32.5 11.1 12.5 9.9 9.7 22.9 16.2 6.0 14.2 11.8 7.1 14.2 2.6 10.4 26.6 22.1 18.9 8.0 19.9 27.7 15.2 7.9 11.5 25.8 8.9 11.7 33.2 4.6 1.5 5.7 10.1 8.3 10.9 2.3 7.2 13.0 23.3 27.4 11.6 1.1 58.0 7.7 4.6 11.5 0.5 17.0 5.4 9.1 44.9 7.1 10.8 5.0 10.8 6.6 14.6 5.3 7.2 2.7 14.5 12.5 4.9 4.2 25.4 15.5 48.6 7.0 6.5 20.3 7.9 3.4 3.5 2.3 10.8 9.3 21.9 8.1 2.0 4.4 3.9 4.6 0.5 5.4 9.6 23.2 3.9 0.8 8.3 4.2 2.8 4.1 15.6 15.0 48.3 9.1 11.7 14.0 24.7 9.9 8.1 39.4 12.0 51.4 102.9 37.1 39.9 18.6 113.5 36.3 44.2 3.2 27.6 3.6 131.3 46.9 24.5 23.3 26.3 22.5 31.2 26.5 23.9 19.9 22.3 22.9 22.1 27.7 33.2 20.7 48.1 12.4 105.4 124.8 9.8 15.8 5.7 29.6 109.5 42.8 25.7 512.1 8.6 13.7 49.7 18.8 11.5 153.0 0.8 156.5 7.0 7.9 9.7 37.2 27.2 9.6 34.3 89.5 6.2 3.2 42.9 8.2 20.0 19.0 32.2 24.7 30.2 28.9 85.8 145.6 16.5 4.1 14.5 16.4 10.5 23.9 27.5 21.4 40.3 75.6 21.8 80.3 100.0 54.7 4.6 9.2 31.6 82.7 32.1 8.2 47.6 19.5 14.8 26.3 38.5 36.4 38.2 22.9 71.4 5.4 2.9 70.1 45.4 4.1 6.7 PPP3CB "CALNA2, CALNB, CNA2, PP2Bbeta" ENSG00000107758 "Protein phosphatase 3 catalytic subunit beta" P16298 10 73436433-73496024 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "skeletal muscle: 379.3;tongue: 179.7" "Cell type enhanced" "Detected in all" "Excitatory neurons: 119.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008233, HPA008823" Uncertain Approved Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA008233: AB_1855661, HPA008823: AB_2668148" "unprognostic (3.05e-1)" "unprognostic (2.54e-1)" "unprognostic (1.50e-1)" "unprognostic (4.93e-2)" "unprognostic (8.93e-2)" "unprognostic (4.28e-2)" "prognostic unfavorable (9.59e-4)" "unprognostic (1.14e-1)" "unprognostic (1.34e-1)" "unprognostic (2.12e-2)" "prognostic favorable (6.96e-5)" "unprognostic (4.73e-2)" "unprognostic (1.51e-1)" "unprognostic (1.01e-1)" "unprognostic (1.45e-1)" "unprognostic (2.66e-1)" "unprognostic (1.68e-2)" 44.8 37.5 40.5 29.8 51.1 19.8 32.1 49.5 63.1 30.3 26.7 41.4 24.2 40.3 34.5 33.1 30.9 28.3 41.3 56.9 29.5 28.1 21.8 23.5 34.9 25.4 25.2 39.6 25.3 39.2 30.6 25.5 28.7 39.1 29.6 57.0 26.6 39.8 379.3 26.3 22.6 48.2 27.2 25.3 24.3 29.0 29.1 32.9 23.5 179.7 36.1 34.3 24.3 44.9 53.7 29.0 50.9 53.0 71.4 98.3 24.5 48.0 65.7 46.1 45.4 18.6 26.8 47.1 15.3 70.0 21.8 28.1 41.6 36.9 64.5 66.6 34.0 20.3 25.0 35.5 42.7 45.2 40.2 70.1 43.5 43.6 58.1 84.7 32.3 40.6 25.6 54.0 94.1 16.9 40.7 41.6 20.7 23.3 83.8 26.9 27.7 22.4 45.1 25.6 27.2 31.5 28.1 69.5 36.4 42.1 52.4 43.2 35.6 36.6 33.7 29.5 66.1 35.8 105.3 33.0 45.3 64.0 21.3 2.2 2.0 3.5 4.0 2.7 4.8 2.7 4.3 4.4 2.1 2.3 3.4 5.1 1.1 3.5 1.7 4.0 7.8 1.9 40.5 51.1 49.5 63.1 56.9 29.5 25.4 25.2 28.7 27.2 29.1 44.9 23.0 3.2 14.3 72.5 31.6 25.6 29.8 13.2 27.3 54.8 25.7 16.9 48.9 14.3 12.8 18.4 20.9 21.0 23.7 11.1 62.6 18.1 11.8 20.0 24.2 21.5 42.6 30.7 119.5 19.4 16.8 32.6 20.4 18.8 21.0 35.4 18.9 14.2 20.3 38.7 111.0 13.2 18.3 31.7 24.2 9.9 33.5 25.2 26.6 51.5 29.6 34.8 18.6 79.4 54.4 16.7 12.9 29.0 34.1 27.1 13.4 34.2 17.6 30.1 6.6 41.8 36.4 43.8 49.2 32.1 31.5 22.2 27.3 28.4 13.1 22.1 PRDX1 "NKEFA, PAGA" ENSG00000117450 "Peroxiredoxin 1" Q06830 1 45510914-45542732 "Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Antioxidant, Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 2690.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004682, HPA007730" Approved Approved Mitochondria NA NA 110000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 27: Brain & Skin - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria "CAB004682: AB_437046, HPA007730: AB_1855204" "unprognostic (1.28e-2)" "unprognostic (4.64e-1)" "unprognostic (2.22e-2)" "unprognostic (3.65e-1)" "unprognostic (2.38e-1)" "unprognostic (3.95e-2)" "prognostic unfavorable (1.17e-5)" "unprognostic (2.47e-1)" "unprognostic (1.31e-1)" "unprognostic (4.68e-2)" "unprognostic (3.05e-2)" "unprognostic (2.90e-1)" "unprognostic (2.39e-2)" "unprognostic (5.99e-2)" "unprognostic (2.88e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (2.89e-4)" 277.8 362.9 642.4 290.2 667.1 86.7 454.3 700.7 747.3 314.1 627.0 326.7 501.4 255.3 459.4 945.8 306.3 297.4 542.9 613.0 700.8 785.5 841.2 340.2 371.4 712.1 706.3 255.5 122.7 214.6 210.0 353.3 711.6 256.0 327.1 347.3 348.6 307.2 571.4 296.5 402.1 329.3 713.5 265.8 355.5 143.7 671.4 262.8 802.3 477.7 603.3 393.2 375.3 766.6 1028.1 1743.7 735.2 942.9 828.4 701.9 1459.3 1134.8 1144.1 1183.0 964.3 932.3 429.2 899.1 1125.9 1237.6 1448.6 967.6 1640.2 1101.3 1193.0 696.9 1266.4 678.6 2042.8 2484.7 361.0 793.6 848.9 610.4 813.6 1201.7 283.8 657.7 1409.7 1044.0 1271.8 292.7 1225.2 829.4 1053.7 772.5 2339.8 2241.0 1867.3 1863.6 934.0 1177.7 2211.5 872.4 987.5 495.1 1035.3 2524.2 73.3 2157.3 760.6 631.1 1208.1 474.8 1071.9 1034.4 1541.5 206.1 1220.5 1678.2 791.4 537.9 278.7 469.3 325.6 111.6 155.7 367.1 205.4 253.8 246.8 209.3 293.9 221.6 150.3 166.6 12.1 123.8 407.5 195.9 438.2 416.3 642.4 667.1 700.7 747.3 613.0 700.8 712.1 706.3 711.6 713.5 671.4 766.6 530.7 522.4 259.0 48.3 330.1 607.3 1115.3 1161.1 745.0 161.3 387.0 510.9 54.9 397.5 685.2 617.9 104.3 1258.6 151.5 339.3 946.9 1015.7 19.7 662.7 281.2 437.8 174.5 304.2 15.5 442.8 1773.2 462.0 500.0 435.5 325.3 463.2 326.3 875.2 1467.4 206.9 17.1 295.0 545.3 366.9 980.7 44.2 498.6 534.8 581.7 12.2 545.7 416.4 62.8 24.1 90.5 804.4 384.9 410.7 612.8 1100.9 995.0 2690.9 919.1 402.2 309.0 279.0 982.6 84.5 329.2 1346.9 528.6 1114.9 270.9 499.4 398.8 1462.7 PRDX3 "AOP-1, AOP1, MER5, SP-22" ENSG00000165672 "Peroxiredoxin 3" P30048 10 119167720-119178812 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Antioxidant, Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 1060.4;Proximal tubular cells: 937.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008656, HPA041488, CAB079909" Enhanced Supported Mitochondria NA NA 1600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB008656: AB_1620979, CAB079909: AB_2809998, HPA041488: AB_2677508" "unprognostic (8.29e-2)" "unprognostic (1.02e-1)" "unprognostic (1.26e-2)" "unprognostic (1.68e-1)" "unprognostic (1.17e-1)" "unprognostic (1.72e-3)" "unprognostic (4.62e-3)" "unprognostic (2.40e-1)" "unprognostic (2.06e-1)" "unprognostic (3.65e-2)" "unprognostic (1.29e-2)" "unprognostic (9.48e-2)" "unprognostic (6.03e-3)" "unprognostic (2.77e-1)" "unprognostic (2.77e-1)" "unprognostic (2.27e-1)" "unprognostic (1.21e-1)" 165.7 335.3 92.4 96.0 92.6 82.3 138.3 101.3 116.0 103.4 139.2 133.3 137.8 87.0 120.8 83.3 116.7 88.0 278.2 95.2 104.5 385.7 571.2 74.9 108.4 97.2 97.1 74.9 96.2 223.8 60.0 126.3 99.0 126.7 139.8 52.5 132.1 131.7 376.0 38.0 132.1 130.0 100.4 76.3 97.5 48.3 98.6 98.3 176.7 402.7 104.0 112.8 65.1 102.7 350.6 392.2 234.1 267.3 241.7 259.8 145.9 244.8 414.8 364.5 380.7 303.4 339.9 407.2 208.8 290.8 173.4 155.5 391.5 296.1 408.8 401.5 411.4 183.7 149.7 542.4 252.5 347.8 212.7 306.8 186.4 292.1 269.7 261.2 268.6 245.2 230.0 82.5 338.7 140.2 265.1 292.7 218.9 264.0 229.3 276.5 339.7 281.5 623.8 164.6 103.0 149.2 259.8 346.1 332.2 201.0 179.6 411.5 190.5 118.3 178.1 170.9 323.1 128.0 200.7 327.0 185.7 507.4 107.3 144.4 429.1 246.9 110.5 369.5 142.7 179.9 145.6 134.6 382.1 149.8 149.5 134.0 239.9 132.8 333.9 214.8 205.7 510.2 92.4 92.6 101.3 116.0 95.2 104.5 97.2 97.1 99.0 100.4 98.6 102.7 61.4 48.1 74.5 14.4 65.1 69.8 117.8 274.0 81.4 27.5 145.2 105.2 236.5 131.5 119.0 147.1 10.4 328.4 50.6 84.5 1060.4 124.5 5.0 105.1 76.0 78.3 110.9 132.8 15.4 75.1 212.0 100.8 116.7 77.3 52.6 131.0 73.2 390.0 247.6 40.4 15.4 132.5 221.8 164.2 96.0 10.5 77.3 127.9 133.4 10.3 158.4 76.9 39.1 12.5 18.8 63.8 99.3 101.2 153.7 95.1 176.1 937.8 163.4 24.8 72.3 63.1 105.3 11.2 23.2 146.4 52.6 155.0 56.1 440.0 207.0 119.6 PRDX5 "ACR1, AOEB166, B166, MGC117264, MGC142283, MGC142285, PLP, PMP20, PRDX6, PRXV, SBBI10" ENSG00000126432 "Peroxiredoxin 5" P30044 11 64318121-64321811 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Antioxidant, Oxidoreductase, Peroxidase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Respiratory ciliated cells: 2430.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008661, HPA037915, HPA037916" Enhanced Supported Mitochondria NA NA 6900000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Mitochondria "CAB008661: AB_1620988, HPA037915: AB_2675735, HPA037916: AB_2675736" "unprognostic (2.75e-1)" "unprognostic (4.08e-1)" "unprognostic (1.33e-1)" "unprognostic (1.46e-1)" "unprognostic (9.43e-2)" "unprognostic (6.71e-3)" "unprognostic (1.08e-3)" "unprognostic (3.11e-1)" "unprognostic (9.30e-2)" "unprognostic (1.07e-3)" "unprognostic (1.57e-2)" "unprognostic (2.20e-1)" "prognostic favorable (1.24e-5)" "unprognostic (8.19e-2)" "unprognostic (2.30e-1)" "unprognostic (9.63e-2)" "unprognostic (5.03e-2)" 181.8 400.3 346.0 112.7 342.6 285.7 170.1 375.9 429.4 227.2 480.2 346.6 213.3 153.7 176.6 448.5 400.3 120.7 467.4 340.4 384.6 377.1 280.3 217.2 110.1 382.8 373.3 246.0 224.9 254.5 313.3 164.1 387.0 165.5 299.6 109.0 286.2 164.4 504.0 181.1 226.1 97.1 365.2 162.9 313.9 150.1 377.8 167.7 354.5 439.6 137.8 192.5 244.8 346.4 225.3 453.4 267.9 444.5 284.3 424.4 308.5 274.9 442.3 199.8 247.4 332.9 451.8 329.2 467.0 447.4 712.6 503.5 253.3 589.4 125.8 456.6 200.8 333.3 728.8 386.3 581.0 127.8 271.3 432.4 757.2 334.9 337.8 387.6 308.4 380.6 191.5 755.6 285.5 572.0 220.9 547.8 402.6 356.5 573.9 210.9 274.5 1178.8 760.1 442.9 224.7 424.9 230.8 506.8 818.8 254.3 370.5 283.3 298.3 281.8 258.6 326.7 123.1 383.1 490.8 392.4 340.7 253.7 223.6 703.9 465.4 630.7 251.0 432.9 218.3 393.5 229.0 205.1 369.8 409.0 224.5 225.9 802.3 368.5 399.0 487.9 297.1 639.6 346.0 342.6 375.9 429.4 340.4 384.6 382.8 373.3 387.0 365.2 377.8 346.4 213.7 266.0 463.4 17.6 182.1 326.5 760.2 1591.9 405.2 159.0 266.2 435.9 617.6 371.8 931.2 450.6 70.9 1122.2 185.8 846.1 1612.1 788.4 79.6 865.2 221.3 204.7 801.9 200.6 12.4 1039.2 1144.0 296.1 365.4 285.9 104.7 299.8 205.6 405.2 476.9 92.5 14.0 1041.6 1072.1 206.5 261.0 294.9 279.0 210.8 435.8 8.4 339.7 309.6 278.1 14.1 15.3 1487.3 641.3 226.8 288.9 401.3 922.4 1468.5 2430.7 150.3 197.2 176.2 433.1 150.2 333.9 482.8 257.7 978.9 165.2 713.3 1231.7 1077.1 PRKAR2B PRKAR2 ENSG00000005249 "Protein kinase cAMP-dependent type II regulatory subunit beta" P31323 7 107044705-107161811 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 135.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 110.2;Excitatory neurons: 146.3;Granulosa cells: 712.1;Theca cells: 271.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 70.7;Daudi: 99.8;K-562: 61.4;U-698: 254.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008421, HPA063879" Enhanced Uncertain Mitochondria NA NA 570000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "HPA008421: AB_1855421, HPA063879: " "unprognostic (3.18e-1)" "unprognostic (2.48e-2)" "prognostic favorable (6.38e-4)" "unprognostic (1.63e-2)" "unprognostic (3.33e-3)" "unprognostic (2.43e-3)" "unprognostic (2.76e-1)" "unprognostic (8.14e-3)" "unprognostic (1.70e-1)" "unprognostic (5.97e-2)" "prognostic favorable (4.03e-4)" "unprognostic (1.50e-1)" "unprognostic (5.12e-3)" "unprognostic (2.39e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (8.74e-4)" "unprognostic (7.15e-2)" 135.8 44.9 10.7 4.8 12.1 14.2 51.3 5.7 17.5 8.0 5.3 11.1 3.6 6.9 4.4 11.2 7.0 4.9 15.5 13.2 9.5 8.8 2.5 7.6 3.8 6.2 10.2 26.4 8.7 6.5 11.4 15.1 8.3 9.2 6.9 7.5 9.9 4.4 1.5 3.7 11.5 5.1 6.9 16.7 9.1 13.6 7.8 2.6 3.5 6.1 4.0 20.3 6.2 10.1 0.1 1.5 9.1 70.7 36.8 0.0 0.1 3.6 11.5 3.0 2.7 0.0 0.2 99.8 0.8 2.3 8.6 0.1 7.1 0.0 5.5 2.8 7.9 33.3 0.1 0.0 10.3 0.6 4.5 0.5 0.0 0.3 0.0 3.1 42.9 5.4 61.4 2.9 0.1 7.5 14.0 0.4 17.3 0.0 2.8 4.0 0.2 0.0 0.1 0.1 11.6 16.7 5.4 1.2 3.9 22.9 2.1 7.0 24.4 3.5 9.2 0.0 7.1 2.1 0.1 254.8 2.5 17.5 33.9 0.6 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.1 0.2 0.3 0.0 0.6 10.7 12.1 5.7 17.5 13.2 9.5 6.2 10.2 8.3 6.9 7.8 10.1 39.6 3.2 1.5 9.8 1.9 2.4 1.6 2.1 0.6 33.5 27.9 10.5 35.9 12.8 5.1 7.3 10.4 0.1 3.7 1.7 0.0 2.5 7.9 1.8 16.2 17.4 0.0 110.2 146.3 0.0 0.6 17.5 3.6 0.9 4.5 712.1 19.2 0.0 1.6 5.0 71.9 1.9 4.1 19.6 26.4 8.5 29.8 64.1 17.8 15.9 17.0 6.4 3.1 60.8 10.9 0.1 2.1 53.0 2.0 3.5 0.0 0.8 5.4 11.9 19.7 5.4 57.7 2.5 6.5 0.7 2.4 0.0 3.7 271.7 2.7 4.6 PTCD1 KIAA0632 ENSG00000106246 "Pentatricopeptide repeat domain 1" O75127 7 99416739-99466163 "Predicted intracellular proteins" "tRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CACO-2: 29.2" "HPA020106, HPA047679" Uncertain Approved Mitochondria NA NA "Cluster 32: T-cells - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "HPA020106: AB_2176551, HPA047679: AB_2680119" "unprognostic (4.70e-2)" "unprognostic (3.38e-2)" "unprognostic (4.19e-2)" "unprognostic (6.05e-2)" "unprognostic (1.17e-1)" "unprognostic (2.11e-2)" "prognostic unfavorable (2.34e-4)" "unprognostic (4.39e-2)" "unprognostic (2.00e-1)" "unprognostic (4.09e-2)" "unprognostic (1.14e-2)" "unprognostic (8.87e-2)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.49e-1)" "unprognostic (1.50e-1)" "unprognostic (7.71e-2)" "unprognostic (7.10e-3)" 3.4 3.6 3.5 2.6 3.5 5.6 3.4 4.2 4.0 3.3 2.8 3.8 2.7 3.7 0.8 4.4 3.8 2.7 4.1 3.2 3.1 3.2 4.7 2.8 3.4 4.1 3.6 3.4 3.6 1.6 2.9 1.8 3.6 4.2 1.3 1.7 3.4 2.1 6.7 4.3 4.0 1.0 3.1 4.9 3.9 4.3 3.6 1.3 3.2 2.6 1.5 3.6 3.4 4.2 4.8 9.8 3.3 9.3 3.1 2.5 9.2 6.6 2.4 4.6 3.3 29.2 5.7 9.6 7.4 1.8 7.7 5.1 4.0 5.9 1.6 7.7 11.2 4.9 8.1 7.2 4.8 5.1 9.0 2.0 3.7 3.8 3.8 3.1 1.4 6.0 10.0 6.4 2.3 13.8 9.0 12.9 6.1 4.8 8.0 5.4 4.3 11.9 2.5 5.1 6.1 6.5 7.4 24.2 6.3 4.7 5.2 5.3 2.7 6.9 8.1 13.7 7.1 9.5 9.1 10.2 7.1 6.7 9.7 1.8 2.0 0.9 3.3 2.3 2.2 1.8 2.1 2.2 1.4 2.5 2.4 3.0 1.9 2.0 1.7 2.1 1.5 1.5 3.5 3.5 4.2 4.0 3.2 3.1 4.1 3.6 3.6 3.1 3.6 4.2 3.5 0.0 5.8 0.0 6.6 6.2 4.0 5.2 4.6 7.9 4.9 4.7 5.8 4.3 4.0 5.5 10.4 9.9 4.1 4.2 1.9 5.3 2.1 4.7 8.6 5.3 7.3 2.5 0.0 6.7 5.6 4.2 3.6 5.2 12.7 12.9 4.6 6.1 6.6 8.4 0.0 6.2 6.1 3.2 6.1 1.8 3.7 3.7 3.6 0.0 3.8 5.6 1.0 0.0 0.0 5.0 2.5 3.0 4.1 3.6 4.5 3.2 5.8 9.3 0.0 8.6 6.7 8.7 7.6 5.1 4.1 5.6 5.7 6.2 6.3 2.6 PTCD3 "DKFZp666K071, FLJ20758" ENSG00000132300 "Pentatricopeptide repeat domain 3" Q96EY7 2 86106223-86142157 "Predicted intracellular proteins, Ribosomal proteins" "Translation regulation" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041154, HPA041382" Supported Supported Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 52: Non-specific - Transcription" Mitochondria "HPA041154: AB_10795488, HPA041382: AB_10795695" "unprognostic (1.16e-2)" "unprognostic (4.47e-2)" "unprognostic (1.37e-2)" "unprognostic (9.30e-3)" "unprognostic (2.40e-2)" "unprognostic (2.54e-1)" "unprognostic (4.92e-3)" "unprognostic (2.06e-2)" "unprognostic (4.78e-2)" "unprognostic (3.78e-1)" "unprognostic (7.42e-3)" "unprognostic (5.49e-3)" "unprognostic (1.26e-1)" "prognostic favorable (6.77e-4)" "unprognostic (3.69e-1)" "unprognostic (7.79e-2)" "prognostic favorable (6.86e-4)" 10.0 15.8 13.1 7.6 14.2 14.7 9.9 15.2 15.9 11.6 16.3 12.6 10.1 11.7 10.2 10.7 11.7 6.4 26.2 13.3 14.5 12.4 16.5 9.6 11.8 13.6 14.0 15.1 10.7 13.1 14.8 9.2 14.7 10.4 13.5 13.2 9.8 7.5 32.8 10.3 11.9 9.0 13.7 12.0 11.8 16.6 13.5 10.5 12.0 36.3 11.1 10.3 10.7 16.7 16.2 37.6 22.0 18.5 16.1 16.6 26.2 32.6 13.8 18.0 18.0 69.9 15.1 39.7 11.8 17.1 18.6 28.9 44.7 17.7 22.9 17.8 37.0 31.8 23.0 59.2 16.3 26.0 23.1 19.8 12.8 13.7 24.4 18.8 15.7 28.6 33.5 14.8 16.0 15.0 21.7 31.0 20.2 31.5 23.9 28.8 30.9 30.6 24.6 31.7 23.9 14.7 15.2 25.0 30.4 20.6 13.2 15.7 11.3 14.2 15.1 14.6 19.2 33.7 47.6 31.6 13.8 29.4 11.1 4.4 9.6 7.6 12.4 7.0 14.6 15.3 11.2 13.2 10.6 16.4 15.1 11.3 0.3 14.3 14.1 10.7 13.9 8.8 13.1 14.2 15.2 15.9 13.3 14.5 13.6 14.0 14.7 13.7 13.5 16.7 17.1 57.7 33.5 50.3 31.0 26.0 26.3 27.7 34.7 61.7 19.2 16.8 105.7 18.6 37.4 23.9 66.7 53.0 30.6 21.7 25.4 18.8 34.8 27.5 33.3 23.5 31.1 39.5 52.9 11.9 27.0 30.5 30.1 24.2 33.6 47.5 21.4 41.7 21.7 37.0 53.1 25.3 20.3 19.6 13.3 22.4 27.1 17.7 8.8 21.5 22.7 49.8 28.8 48.7 53.4 15.0 19.2 19.5 26.4 23.7 23.2 30.1 26.2 65.3 13.1 36.3 21.3 98.3 62.4 28.7 24.7 36.7 31.8 47.9 38.5 20.4 PTGES2 "C9orf15, FLJ14038" ENSG00000148334 "Prostaglandin E synthase 2" Q9H7Z7 9 128120693-128128462 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Cardiomyocytes: 700.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020631, HPA020733" Approved Approved Mitochondria No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA020631: AB_1855887, HPA020733: AB_2670508" "unprognostic (1.23e-1)" "unprognostic (1.86e-2)" "unprognostic (1.60e-1)" "unprognostic (1.95e-2)" "unprognostic (1.55e-1)" "unprognostic (1.68e-2)" "unprognostic (5.13e-3)" "unprognostic (2.56e-1)" "unprognostic (1.57e-1)" "unprognostic (7.10e-2)" "unprognostic (2.81e-2)" "unprognostic (4.33e-2)" "prognostic favorable (5.83e-7)" "unprognostic (2.10e-2)" "unprognostic (1.46e-1)" "unprognostic (1.10e-1)" "unprognostic (1.05e-1)" 18.1 49.8 31.6 15.6 33.9 6.5 16.0 29.1 45.8 18.1 32.4 30.6 27.5 21.6 4.0 35.3 17.6 11.4 95.0 35.6 33.0 36.4 37.7 14.8 17.6 31.5 31.5 16.1 37.6 35.2 41.4 9.7 32.1 24.6 9.2 10.0 26.1 16.8 117.9 20.9 23.8 7.5 27.3 21.1 29.6 14.5 31.5 11.9 23.5 78.7 9.7 22.3 22.0 31.7 46.1 114.0 15.5 54.4 13.5 12.8 47.9 30.7 20.6 48.6 24.9 86.9 75.6 43.5 45.7 15.9 36.9 108.8 22.5 47.1 6.5 28.3 62.3 21.0 92.7 79.5 41.0 42.1 39.5 18.6 32.3 39.5 26.9 14.2 31.6 47.8 50.2 26.4 16.7 130.0 56.9 75.6 42.7 58.7 113.9 39.6 26.5 111.6 32.8 33.1 69.1 45.6 47.3 86.3 34.2 6.7 78.7 23.5 34.0 46.3 50.2 62.8 63.1 48.9 25.5 38.3 39.1 33.2 44.5 1.4 3.3 0.7 3.1 3.7 3.8 3.8 2.2 3.5 4.3 2.7 2.4 3.0 0.6 2.7 1.8 5.8 3.1 1.9 31.6 33.9 29.1 45.8 35.6 33.0 31.5 31.5 32.1 27.3 31.5 31.7 18.8 16.0 6.4 10.4 32.0 22.9 38.1 32.7 25.0 37.8 34.2 36.3 700.2 51.5 25.9 23.9 20.9 82.1 30.8 86.1 146.8 74.6 2.1 12.7 20.9 29.4 45.1 13.2 15.5 51.8 62.1 32.7 46.4 17.3 14.7 31.9 13.9 37.8 57.6 37.0 15.8 62.2 46.8 25.3 43.6 4.8 30.7 30.8 56.9 3.7 105.7 21.9 38.1 12.1 7.2 57.6 60.4 21.8 45.4 68.0 93.4 99.3 9.3 44.8 19.7 17.8 37.2 3.6 45.6 48.3 24.6 66.6 25.6 84.1 105.5 52.9 PTPMT1 "DUSP23, MOSP, PLIP" ENSG00000110536 "Protein tyrosine phosphatase mitochondrial 1" Q8WUK0 11 47565430-47573461 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 235.1;Late spermatids: 640.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043932, HPA060060" Approved Enhanced Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 71: Testis - DNA repair" "Cluster 6: T47d - Mammary gland" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "HPA043932: AB_2678738, HPA060060: " "unprognostic (6.61e-2)" "unprognostic (2.09e-1)" "unprognostic (1.28e-1)" "unprognostic (2.37e-3)" "unprognostic (1.02e-1)" "unprognostic (1.26e-2)" "prognostic unfavorable (3.04e-5)" "unprognostic (3.29e-2)" "unprognostic (2.77e-2)" "unprognostic (1.93e-3)" "unprognostic (6.76e-2)" "unprognostic (1.72e-1)" "unprognostic (2.68e-3)" "unprognostic (1.21e-1)" "unprognostic (5.39e-1)" "unprognostic (2.17e-2)" "unprognostic (1.75e-1)" 38.8 56.5 15.0 5.3 16.1 9.0 37.4 15.8 17.4 31.1 16.6 31.0 7.6 32.8 7.8 34.8 29.5 4.2 27.7 14.4 16.5 37.6 40.6 36.5 6.1 15.6 16.3 28.0 44.7 9.6 41.9 6.7 15.8 32.7 3.9 4.2 37.1 5.9 41.0 28.1 23.4 4.7 16.0 28.9 39.2 105.4 17.0 4.3 30.6 5.8 4.9 27.5 28.1 16.0 34.5 19.4 2.3 17.8 17.5 11.4 7.0 20.1 17.1 19.4 16.8 27.9 17.6 27.9 22.1 14.7 16.8 30.6 16.9 20.4 16.6 31.4 57.3 12.9 43.8 43.4 25.7 25.2 17.1 12.7 21.9 8.8 24.0 11.2 13.7 26.2 32.6 19.5 14.2 65.4 21.4 41.0 18.8 3.9 37.7 38.6 16.7 22.3 22.5 23.3 15.5 21.4 33.8 11.1 23.2 7.2 53.1 32.7 16.6 13.6 23.3 28.6 33.1 27.1 22.6 18.6 13.6 23.3 10.0 11.2 38.0 38.2 24.8 36.8 23.0 33.7 22.7 26.2 44.9 30.3 22.3 21.0 3.1 26.1 34.6 64.6 28.5 28.8 15.0 16.1 15.8 17.4 14.4 16.5 15.6 16.3 15.8 16.0 17.0 16.0 26.8 22.4 35.0 14.4 31.8 17.8 15.8 58.5 34.1 14.4 64.9 78.4 5.8 45.8 38.6 40.5 4.2 72.2 34.7 19.9 72.4 95.3 235.1 48.0 23.9 24.6 31.3 30.1 8.2 85.8 66.3 23.9 28.1 25.6 17.1 16.5 29.6 39.8 62.4 5.0 10.8 45.7 48.8 32.6 21.2 640.8 46.6 45.6 46.2 6.5 56.2 74.9 41.2 9.5 14.6 106.2 38.8 46.6 61.0 26.0 37.9 72.8 57.2 15.7 19.7 17.3 28.1 179.8 28.6 55.0 17.3 76.8 25.9 21.3 62.7 22.0 PTPRH SAP-1 ENSG00000080031 "Protein tyrosine phosphatase receptor type H" Q9HD43 19 55181247-55209506 "Enzymes, Metabolic proteins, Predicted membrane proteins" Apoptosis "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 24.2;intestine: 68.6;stomach 1: 23.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 123.6;Gastric mucus-secreting cells: 60.1;Paneth cells: 94.9;Proximal enterocytes: 113.1" "Cancer enhanced" "Detected in many" "pancreatic cancer: 16.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HHSteC: 11.8;K-562: 15.0;OE19: 30.9;SK-MEL-30: 22.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA042300 Approved Mitochondria NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA042300: AB_10796900" "unprognostic (1.87e-1)" "unprognostic (1.10e-1)" "unprognostic (2.59e-1)" "unprognostic (7.57e-3)" "unprognostic (5.01e-3)" "unprognostic (8.14e-2)" "unprognostic (1.15e-1)" "unprognostic (1.96e-3)" "unprognostic (1.60e-2)" "unprognostic (1.06e-1)" "unprognostic (9.96e-2)" "unprognostic (6.16e-2)" "unprognostic (1.47e-11)" "unprognostic (4.08e-3)" "unprognostic (2.47e-1)" "unprognostic (1.52e-2)" "unprognostic (1.57e-1)" 1.3 16.9 1.7 3.6 4.4 0.0 0.6 5.2 3.0 0.8 0.9 27.9 67.7 0.7 0.1 0.3 0.5 24.2 1.1 1.7 3.4 0.2 13.3 0.1 0.1 7.1 4.9 0.3 4.6 0.1 5.1 0.1 5.7 0.2 21.2 1.3 0.1 0.0 0.0 0.1 68.6 2.1 3.8 22.2 23.6 0.8 4.8 0.0 0.1 0.0 0.1 5.7 0.6 7.2 6.9 4.2 0.0 1.6 1.3 3.6 0.1 0.1 3.6 0.7 1.4 1.8 9.5 0.0 0.3 0.6 8.2 0.0 0.0 0.0 0.8 0.1 0.1 0.5 0.1 4.9 11.8 0.0 4.8 1.0 2.9 2.3 3.6 0.4 0.2 0.0 15.0 0.6 0.0 0.0 0.0 0.3 0.0 30.9 9.8 0.0 0.0 0.5 0.0 0.0 0.4 1.0 0.0 4.2 22.4 0.0 0.0 1.9 0.0 1.0 1.4 0.5 0.1 0.0 3.7 0.0 1.1 0.1 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.7 4.4 5.2 3.0 1.7 3.4 7.1 4.9 5.7 3.8 4.8 7.2 0.3 0.0 0.0 0.0 0.4 1.8 2.8 1.9 0.0 0.1 0.2 0.3 0.6 21.5 3.8 1.8 0.0 0.0 0.0 123.6 0.0 15.5 0.0 1.2 1.0 0.5 4.8 0.0 0.8 25.8 0.1 1.1 60.1 0.5 0.0 4.1 0.7 5.7 0.2 16.8 0.7 20.8 0.0 0.0 1.1 0.3 0.0 0.4 0.0 1.0 0.6 0.2 1.0 0.0 5.8 26.9 94.9 0.0 0.4 3.4 113.1 0.0 4.5 0.5 0.0 3.1 1.8 0.3 0.2 0.0 1.1 0.1 0.5 3.6 18.7 19.7 PTRH2 "BIT1, CFAP37, CGI-147, PTH2" ENSG00000141378 "Peptidyl-tRNA hydrolase 2" Q9Y3E5 17 59674636-59707626 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" Apoptosis Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012897 Supported Supported Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 68: Epididymis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA012897: AB_1855949" "unprognostic (2.26e-1)" "unprognostic (2.80e-2)" "unprognostic (1.02e-2)" "unprognostic (3.89e-2)" "unprognostic (1.31e-2)" "unprognostic (3.38e-2)" "prognostic unfavorable (1.50e-4)" "unprognostic (6.38e-2)" "unprognostic (2.02e-1)" "unprognostic (9.59e-3)" "unprognostic (2.72e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.01e-8)" "unprognostic (5.43e-3)" "unprognostic (6.82e-2)" "unprognostic (1.32e-1)" "unprognostic (1.49e-2)" 20.8 25.9 24.3 17.3 25.1 14.5 27.6 25.0 31.9 19.7 23.6 24.1 15.3 18.8 48.5 18.1 18.4 18.2 14.5 25.1 26.1 18.5 45.7 14.7 19.0 25.9 26.1 16.9 19.5 18.6 14.1 18.6 26.7 20.7 27.5 10.2 15.9 18.6 25.0 15.7 13.2 22.9 24.8 17.5 16.1 19.5 24.9 17.3 16.2 20.9 24.1 44.0 11.8 27.4 75.9 142.9 44.3 40.8 84.8 72.6 47.4 70.6 63.8 60.7 89.0 94.1 57.7 54.1 105.0 60.9 101.1 73.3 98.4 93.8 89.4 104.2 133.2 96.7 72.3 176.2 129.4 86.0 52.5 82.0 120.9 93.9 108.5 42.8 102.5 37.4 111.3 58.2 92.4 187.9 74.2 71.2 38.0 194.5 113.4 39.1 74.8 80.7 103.7 109.2 57.9 74.2 36.7 39.6 91.5 50.7 93.1 61.1 67.2 77.8 77.8 47.1 77.9 73.6 91.9 82.3 50.7 54.4 60.4 6.1 69.0 2.9 22.7 67.4 30.9 43.1 26.3 25.7 50.0 33.1 37.4 27.0 29.0 34.8 86.0 59.4 34.0 37.9 24.3 25.1 25.0 31.9 25.1 26.1 25.9 26.1 26.7 24.8 24.9 27.4 21.4 16.0 13.6 5.5 18.7 36.7 50.1 48.1 27.9 4.1 17.1 22.4 15.4 11.5 51.6 11.0 4.2 26.8 13.0 8.9 11.7 27.2 22.1 23.4 33.1 22.5 6.7 17.9 9.8 25.6 25.0 29.7 17.3 24.1 22.8 12.8 12.8 31.5 16.9 8.4 9.1 10.3 22.4 9.7 17.2 12.0 17.4 14.6 14.2 2.8 11.4 7.2 13.4 7.5 11.5 28.8 12.3 9.8 24.8 35.1 10.0 16.5 33.3 3.4 13.1 25.4 32.2 33.4 13.3 21.3 35.7 31.7 12.6 22.4 16.7 37.5 PYCR2 P5CR2 ENSG00000143811 "Pyrroline-5-carboxylate reductase 2" Q96C36 1 225919877-225924340 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Proline biosynthesis" Oxidoreductase "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA056873 Approved Approved Mitochondria NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 51: Myeloid cells - Hemostasis" Mitochondria "HPA056873: AB_2683263" "unprognostic (1.11e-1)" "unprognostic (8.08e-2)" "prognostic unfavorable (5.02e-5)" "unprognostic (2.91e-2)" "unprognostic (1.76e-1)" "unprognostic (1.03e-1)" "unprognostic (4.20e-3)" "unprognostic (1.56e-2)" "unprognostic (6.89e-2)" "unprognostic (1.12e-1)" "unprognostic (9.07e-3)" "unprognostic (1.56e-1)" "prognostic unfavorable (1.42e-6)" "unprognostic (9.69e-2)" "unprognostic (2.61e-1)" "unprognostic (6.44e-2)" "unprognostic (1.16e-3)" 38.0 71.7 53.2 35.8 62.4 47.3 35.8 68.1 54.2 46.4 51.8 39.6 22.3 48.5 26.4 32.3 44.7 22.4 62.3 50.4 61.3 40.2 40.3 38.2 47.2 69.0 61.2 47.9 47.2 42.0 57.0 28.5 66.0 39.6 18.3 34.0 39.6 40.9 66.8 28.3 34.4 25.7 68.6 49.5 38.9 34.4 59.2 43.9 30.0 49.1 33.9 50.3 33.3 72.5 72.6 59.6 35.0 59.1 38.8 40.0 73.2 74.8 46.3 49.7 44.1 77.2 58.3 126.1 156.6 55.0 39.1 81.6 50.5 58.6 28.3 154.6 107.5 120.6 60.2 81.5 59.8 107.9 189.1 38.8 72.3 56.1 64.1 44.1 47.8 103.7 178.4 81.6 50.9 60.5 135.8 120.9 196.0 112.8 80.4 120.2 79.0 263.6 65.2 58.3 44.0 56.7 62.4 48.7 161.0 27.9 62.3 202.0 40.3 38.4 46.5 82.9 104.4 129.9 156.2 127.4 60.7 80.6 109.3 38.4 19.6 39.6 45.5 29.2 47.8 34.4 43.8 42.4 31.3 41.9 74.9 62.4 13.3 67.9 26.3 59.2 44.0 45.1 53.2 62.4 68.1 54.2 50.4 61.3 69.0 61.2 66.0 68.6 59.2 72.5 28.0 19.2 22.8 11.4 31.6 14.8 64.6 53.4 8.0 15.6 24.3 21.2 47.6 20.0 24.8 35.0 14.6 90.6 39.1 12.9 49.0 50.0 8.2 92.8 25.6 26.7 26.5 58.7 4.6 34.0 46.3 23.7 10.2 31.8 38.7 74.9 21.0 16.6 40.0 13.5 5.8 17.8 57.0 20.4 19.8 8.8 38.2 31.5 33.8 8.4 46.4 46.9 46.4 5.5 29.3 29.1 15.8 37.6 23.1 42.1 18.3 35.8 55.4 42.7 26.3 19.8 24.4 40.1 46.2 9.4 12.8 41.7 34.9 44.9 16.1 40.4 PYROXD2 "C10orf33, FLJ23849" ENSG00000119943 "Pyridine nucleotide-disulphide oxidoreductase domain 2" Q8N2H3 10 98383565-98415182 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "eosinophil: 189.8" "Lineage enriched" "Detected in many" 4 "granulocytes: 189.8" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 46.1;U-937: 31.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA037566, HPA037567, HPA067394" Approved Approved Mitochondria NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA037566: AB_10670385, HPA037567: AB_2675550, HPA067394: AB_2685832" "unprognostic (2.35e-2)" "unprognostic (1.38e-1)" "unprognostic (1.79e-2)" "unprognostic (2.41e-2)" "unprognostic (1.10e-3)" "unprognostic (6.76e-2)" "unprognostic (1.27e-2)" "unprognostic (3.38e-2)" "unprognostic (2.69e-1)" "unprognostic (3.34e-1)" "unprognostic (2.20e-1)" "unprognostic (1.63e-1)" "unprognostic (9.05e-2)" "unprognostic (2.74e-1)" "unprognostic (1.33e-1)" "unprognostic (1.26e-2)" "prognostic favorable (3.37e-4)" 10.2 14.5 6.4 2.2 6.9 2.6 8.4 6.7 7.8 9.1 9.6 7.2 2.0 5.5 8.3 2.5 9.4 4.2 10.7 6.3 6.4 6.3 12.2 4.3 2.6 7.3 7.1 9.2 3.5 2.8 4.7 4.2 7.4 10.5 4.7 0.7 22.4 4.1 9.3 2.9 3.7 5.7 7.0 5.1 5.3 3.7 7.1 2.3 8.6 10.4 1.4 9.7 6.3 8.0 3.6 8.9 4.9 0.2 7.6 15.1 1.9 5.8 18.0 3.2 6.1 0.0 12.3 0.0 10.2 6.2 0.9 1.8 1.5 2.0 3.3 0.3 1.4 7.3 16.1 0.8 9.7 0.1 16.2 8.9 2.6 2.6 3.1 46.1 2.5 3.4 0.2 0.2 4.9 11.1 0.2 17.2 1.4 7.0 3.0 2.3 1.9 0.1 4.7 5.5 0.3 0.1 6.4 0.8 4.6 6.7 5.1 8.1 3.3 0.0 3.6 1.1 5.9 1.2 0.8 0.0 5.7 31.5 0.5 5.4 0.3 189.8 6.1 0.0 1.3 0.0 2.1 5.2 1.9 0.2 1.2 3.6 0.3 44.5 0.0 0.3 0.6 1.8 6.4 6.9 6.7 7.8 6.3 6.4 7.3 7.1 7.4 7.0 7.1 8.0 3.8 9.6 5.1 19.9 1.3 0.5 6.1 9.7 4.0 0.4 15.0 18.4 11.2 5.7 9.5 1.8 0.0 5.6 6.5 3.5 7.9 3.8 0.2 4.1 4.9 4.6 1.2 1.7 3.4 2.4 3.8 7.2 11.2 3.2 2.5 11.2 4.6 2.9 9.8 0.0 4.3 4.9 8.2 3.2 6.6 0.9 3.4 2.0 1.8 5.6 1.8 2.3 19.6 1.5 9.5 1.7 1.6 3.8 0.5 2.7 2.2 12.1 12.2 0.8 6.6 9.7 5.9 2.9 1.5 0.8 0.6 1.8 5.4 17.8 6.3 10.0 QDPR "DHPR, PKU2, SDR33C1" ENSG00000151552 "Quinoid dihydropteridine reductase" P09417 4 17460261-17512206 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tetrahydrobiopterin biosynthesis" Oxidoreductase "Disease variant, Phenylketonuria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 752.2;choroid plexus: 301.8" "Cell type enhanced" "Detected in all" "Hepatocytes: 337.6;Muller glia cells: 387.2;Oligodendrocytes: 481.3;Proximal tubular cells: 527.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058951, HPA065649" Enhanced Approved Mitochondria NA NA 2500000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA058951: AB_2683861, HPA065649: AB_2685526" "unprognostic (1.30e-2)" "unprognostic (4.29e-1)" "unprognostic (8.27e-2)" "unprognostic (2.52e-1)" "unprognostic (1.21e-1)" "unprognostic (1.20e-1)" "unprognostic (3.29e-3)" "unprognostic (3.80e-3)" "unprognostic (1.19e-1)" "unprognostic (1.45e-1)" "unprognostic (6.82e-3)" "unprognostic (2.07e-1)" "prognostic favorable (7.84e-6)" "unprognostic (1.58e-1)" "unprognostic (2.60e-1)" "unprognostic (9.01e-2)" "unprognostic (3.19e-1)" 66.6 74.3 515.1 10.2 720.1 15.1 26.4 696.9 571.9 15.8 301.8 21.2 25.6 16.5 40.1 15.6 17.3 17.7 43.4 457.6 578.5 110.1 197.2 23.3 11.9 663.0 752.2 18.3 28.8 49.9 32.7 11.8 688.6 28.7 17.0 40.1 36.3 19.5 108.6 16.2 23.9 17.9 524.9 14.3 23.7 12.4 602.6 13.6 22.1 61.2 13.3 14.5 15.1 663.7 33.1 62.5 30.2 35.8 66.1 32.3 41.5 43.2 22.3 47.5 41.6 52.2 46.4 12.2 28.0 30.3 50.8 18.4 40.3 58.4 33.7 35.3 7.3 34.8 33.4 128.3 37.3 46.2 2.9 40.8 35.6 31.6 40.3 25.9 24.5 33.2 37.0 29.0 50.6 19.2 65.0 77.8 44.8 36.7 45.4 27.0 21.0 52.2 48.2 17.5 47.1 64.3 31.9 6.7 156.6 35.0 15.7 19.0 37.7 23.6 41.1 26.5 38.2 43.1 67.7 85.3 52.0 43.1 41.7 0.3 38.9 3.0 31.3 61.3 29.8 18.6 33.1 32.3 48.3 18.3 37.4 32.6 1.1 29.8 48.4 115.1 20.3 34.4 515.1 720.1 696.9 571.9 457.6 578.5 663.0 752.2 688.6 524.9 602.6 663.7 20.3 28.9 31.5 10.7 14.8 20.0 21.3 32.2 18.8 36.2 37.6 28.3 74.4 50.1 19.5 38.6 8.4 69.6 22.8 13.7 109.5 41.1 1.0 11.8 19.1 17.2 174.3 30.1 23.1 23.4 34.2 27.1 27.5 17.8 25.4 42.3 20.7 337.6 80.3 82.4 21.9 31.1 34.6 38.1 23.9 4.8 22.7 32.2 152.9 12.2 23.4 387.2 16.5 15.1 481.3 16.9 11.6 38.0 23.6 23.2 41.4 527.2 6.2 31.4 26.3 27.5 25.4 3.3 58.9 29.7 16.1 18.3 18.5 90.0 35.7 17.3 QTRT1 TGT ENSG00000213339 "Queuine tRNA-ribosyltransferase catalytic subunit 1" Q9BXR0 19 10701430-10713437 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "tRNA processing" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Intestinal goblet cells: 260.9;Paneth cells: 224.5;Proximal enterocytes: 261.8;Undifferentiated cells: 280.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042695, HPA048651, HPA049440" Approved Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA042695: AB_2678119, HPA048651: AB_2680477, HPA049440: AB_2680767" "unprognostic (6.19e-2)" "prognostic favorable (7.63e-5)" "unprognostic (2.90e-2)" "unprognostic (3.05e-1)" "unprognostic (4.90e-2)" "prognostic favorable (4.90e-4)" "unprognostic (2.52e-1)" "unprognostic (8.76e-3)" "unprognostic (3.88e-1)" "unprognostic (4.81e-3)" "prognostic favorable (2.13e-4)" "unprognostic (1.14e-2)" "prognostic unfavorable (1.13e-6)" "unprognostic (2.04e-2)" "unprognostic (1.66e-1)" "unprognostic (3.13e-1)" "unprognostic (1.01e-3)" 17.2 27.1 11.2 11.8 11.4 13.4 18.1 10.0 15.9 18.4 9.4 20.0 10.3 22.7 2.7 20.5 20.9 7.3 21.4 11.8 11.3 18.3 30.2 12.5 12.2 10.8 10.6 24.4 51.9 9.6 17.6 7.7 11.1 16.9 5.0 6.1 22.3 9.2 20.5 18.3 15.2 6.1 10.8 14.8 20.7 6.4 11.3 7.0 20.7 10.2 5.1 17.6 16.4 11.6 41.5 32.3 14.6 44.1 15.3 18.2 19.7 20.8 18.3 23.8 22.9 25.6 15.0 47.1 50.1 11.5 14.4 26.6 13.8 24.9 7.7 28.1 20.8 30.4 13.3 55.7 26.6 46.4 25.7 27.8 20.3 15.3 22.1 10.5 24.2 25.5 35.0 50.2 11.8 64.2 39.7 56.5 40.3 25.3 53.5 41.2 19.9 72.2 18.8 26.1 48.4 21.6 33.0 33.4 27.8 6.2 21.5 19.0 19.5 35.0 20.3 58.2 49.7 56.7 48.3 23.3 19.3 55.0 44.4 1.9 16.6 0.4 29.6 31.4 37.4 42.0 31.7 26.4 34.0 40.8 33.3 27.5 1.3 43.9 16.6 39.8 37.9 21.3 11.2 11.4 10.0 15.9 11.8 11.3 10.8 10.6 11.1 10.8 11.3 11.6 23.2 0.0 4.5 47.3 36.6 63.7 63.5 59.0 65.4 36.7 42.6 48.6 7.3 30.0 24.5 57.0 50.1 47.8 27.3 157.0 64.6 25.8 1.6 19.8 28.8 24.7 192.5 30.3 32.8 27.6 39.7 33.5 23.9 18.8 16.5 43.7 18.2 33.9 28.8 90.9 31.4 260.9 42.7 15.8 30.9 2.6 50.7 12.8 49.8 8.4 10.5 22.0 7.2 21.6 30.0 13.9 224.5 37.6 53.2 43.6 261.8 80.3 22.6 57.9 19.7 40.7 31.1 12.9 24.6 36.9 41.9 28.0 27.0 67.4 280.7 37.2 RARS2 "DALRD2, dJ382I10.6, MGC14993, MGC23778, PRO1992, RARSL" ENSG00000146282 "Arginyl-tRNA synthetase 2, mitochondrial" Q5T160 6 87513938-87589987 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Neurodegeneration, Pontocerebellar hypoplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039987, HPA042645" Uncertain Approved Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 1: K-562 - Erythropoiesis" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "HPA039987: AB_2676786, HPA042645: AB_2678097" "unprognostic (1.49e-2)" "unprognostic (1.08e-1)" "unprognostic (5.03e-2)" "unprognostic (6.98e-2)" "unprognostic (9.27e-2)" "unprognostic (5.41e-2)" "unprognostic (6.61e-2)" "unprognostic (4.30e-2)" "unprognostic (1.88e-1)" "unprognostic (1.08e-3)" "unprognostic (8.28e-2)" "unprognostic (2.20e-1)" "unprognostic (7.56e-3)" "unprognostic (1.62e-1)" "unprognostic (1.89e-2)" "unprognostic (5.73e-2)" "unprognostic (7.16e-3)" 24.0 39.6 10.8 15.8 11.8 19.3 21.3 14.7 11.6 21.5 19.2 20.8 17.8 21.8 18.6 17.7 19.7 19.0 22.7 10.4 11.4 20.5 27.9 18.3 16.8 11.5 11.6 18.5 24.0 21.4 17.5 22.2 11.8 18.8 22.7 25.9 20.8 13.6 22.5 18.5 22.6 21.5 11.0 18.5 19.2 25.3 12.5 18.5 20.6 19.3 19.0 20.6 18.2 15.5 19.8 19.1 45.1 49.8 44.6 47.5 31.9 46.6 54.2 30.8 38.6 36.6 21.6 25.0 26.9 47.4 32.0 26.7 37.9 25.8 43.2 18.0 36.0 25.7 24.4 58.7 56.1 30.7 21.3 48.9 24.6 26.4 33.1 44.5 41.0 25.7 59.6 24.4 46.8 35.2 10.0 32.8 29.2 42.3 20.0 19.9 45.9 22.2 38.5 40.1 40.8 54.7 24.8 12.1 33.1 38.2 22.5 45.8 28.1 21.2 16.8 22.8 38.4 25.6 45.1 21.1 32.2 31.8 36.6 18.8 17.8 22.7 16.1 18.6 19.0 15.1 20.4 15.1 15.6 16.2 19.9 16.9 11.9 18.6 20.7 17.9 27.9 15.4 10.8 11.8 14.7 11.6 10.4 11.4 11.5 11.6 11.8 11.0 12.5 15.5 34.4 19.2 15.6 30.0 21.2 17.3 35.4 51.3 12.5 13.9 17.3 16.8 19.9 10.0 37.8 11.0 20.9 31.0 18.1 14.6 45.0 32.9 95.3 23.5 29.3 22.8 9.0 7.4 46.8 46.9 45.5 28.3 12.8 20.3 18.3 27.9 23.6 15.5 20.5 6.7 59.0 23.5 44.7 13.5 14.1 50.6 25.4 15.0 19.6 38.4 22.6 13.6 19.6 56.3 63.9 37.6 21.2 24.0 20.7 30.8 57.2 32.9 24.2 20.3 26.3 18.9 30.0 61.8 33.7 14.1 18.0 39.5 20.6 51.4 27.0 33.9 RASGEF1C FLJ35841 ENSG00000146090 "RasGEF domain family member 1C" Q8N431 5 180100795-180209211 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 21.9;testis: 5.8" "Cell type enriched" "Detected in some" 9 "Microglial cells: 188.3" "Cancer enhanced" "Detected in some" "glioma: 2.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.2;HEK 293: 1.7;MCF7: 2.2;SCLC-21H: 7.6;U-2 OS: 2.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028242 Uncertain Approved Mitochondria NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "HPA028242: AB_10602294" "unprognostic (2.21e-1)" "unprognostic (2.18e-1)" "unprognostic (2.23e-1)" "unprognostic (4.75e-4)" "unprognostic (4.65e-2)" "unprognostic (4.04e-2)" "unprognostic (3.84e-2)" "unprognostic (1.02e-3)" "unprognostic (2.02e-1)" "unprognostic (1.16e-1)" "unprognostic (2.35e-2)" "unprognostic (2.34e-1)" "unprognostic (1.65e-4)" "unprognostic (5.89e-2)" "unprognostic (8.25e-3)" "unprognostic (3.70e-1)" "unprognostic (1.77e-2)" 0.3 0.2 6.2 0.2 16.4 0.0 0.4 21.9 8.5 1.3 0.0 3.4 0.1 0.0 0.1 0.3 0.5 0.3 1.3 7.1 3.2 0.2 0.0 0.0 0.0 7.3 4.4 0.1 0.1 0.0 0.1 0.1 7.5 0.9 0.2 0.3 1.1 0.9 0.0 0.5 0.8 0.1 5.2 0.0 0.7 5.8 4.1 0.0 1.1 0.0 0.0 0.7 1.1 7.6 0.0 0.0 0.2 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.1 0.0 2.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.3 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 2.4 0.0 0.0 0.0 1.3 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 16.4 21.9 8.5 7.1 3.2 7.3 4.4 7.5 5.2 4.1 7.6 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.2 1.8 1.1 0.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 3.4 0.2 0.0 0.5 0.0 0.0 20.2 0.0 0.6 0.1 0.0 0.5 0.0 1.5 0.0 0.0 0.1 0.0 12.5 0.0 0.0 0.0 0.0 3.8 0.0 0.1 0.0 188.3 0.0 0.2 0.0 15.1 19.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 16.7 1.0 0.0 0.0 1.9 0.0 0.5 0.0 0.0 RBFA "C18orf22, FLJ21172, HsT169" ENSG00000101546 "Ribosome binding factor A" Q8N0V3 18 80034389-80050651 "Predicted intracellular proteins" "rRNA processing" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040485, HPA041479" Approved Approved Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 85: Liver - Metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA040485: AB_10795368, HPA041479: AB_10795697" "unprognostic (5.31e-3)" "unprognostic (3.21e-2)" "unprognostic (1.87e-1)" "unprognostic (4.55e-2)" "unprognostic (7.33e-2)" "unprognostic (5.00e-3)" "prognostic unfavorable (2.06e-6)" "unprognostic (2.98e-1)" "unprognostic (7.98e-2)" "unprognostic (7.22e-2)" "unprognostic (4.28e-2)" "unprognostic (3.76e-2)" "unprognostic (2.43e-1)" "unprognostic (3.23e-1)" "unprognostic (1.78e-1)" "unprognostic (3.82e-1)" "unprognostic (5.00e-3)" 18.6 19.9 6.2 9.8 6.1 13.6 17.8 8.1 6.6 13.6 4.7 13.6 12.0 12.4 5.5 17.6 11.0 5.9 18.3 6.3 6.3 14.8 31.3 10.6 8.5 5.8 5.4 10.1 16.7 9.1 8.9 8.3 5.8 11.6 7.9 5.9 12.7 6.8 22.3 20.0 10.9 10.0 5.4 12.4 11.9 12.1 5.8 10.3 11.0 13.3 10.7 13.4 14.2 6.4 28.4 32.6 20.5 20.0 17.5 20.2 27.7 24.0 11.9 25.8 21.9 19.1 22.1 58.6 8.9 16.5 22.6 26.1 21.8 26.1 20.5 22.1 23.9 35.3 24.6 53.0 14.6 55.7 16.7 18.8 24.9 18.6 26.3 11.3 22.4 35.3 19.1 35.7 15.5 30.0 55.6 38.4 22.4 17.7 30.6 38.0 19.6 72.5 26.8 35.2 35.7 21.3 21.0 23.4 17.3 17.0 17.7 29.5 19.7 37.6 37.2 5.5 27.0 14.1 24.5 48.7 22.1 46.2 22.4 0.0 4.8 0.0 6.4 6.5 10.1 8.9 6.5 6.4 7.6 6.5 7.4 6.8 0.2 7.3 10.3 5.7 5.5 5.3 6.2 6.1 8.1 6.6 6.3 6.3 5.8 5.4 5.8 5.4 5.8 6.4 25.4 32.1 10.9 14.0 24.1 18.5 24.4 29.8 25.6 13.5 29.2 32.5 12.2 18.6 24.4 27.6 18.8 50.1 14.8 9.9 31.3 28.4 17.7 23.7 39.0 20.3 20.9 29.9 18.3 24.2 49.9 24.7 19.4 20.9 13.3 34.5 15.7 40.8 24.4 32.0 17.5 21.7 14.2 8.2 20.5 17.0 19.0 15.2 33.8 12.2 9.6 8.0 19.6 19.6 14.1 21.3 7.6 18.4 26.2 23.8 13.7 46.4 19.4 21.8 19.7 17.3 26.3 37.7 49.2 38.2 23.4 24.9 16.7 47.5 25.5 20.9 RHOT2 "ARHT2, C16orf39, MIRO-2" ENSG00000140983 "Ras homolog family member T2" Q8IXI1 16 668105-674174 "Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 264.8;Rod photoreceptor cells: 284.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012624, HPA012895" Approved Supported Mitochondria NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 9: Photoreceptor cells - Phototransduction" Mitochondria "HPA012624: AB_1856272, HPA012895: AB_1856271" "unprognostic (1.59e-1)" "unprognostic (8.24e-2)" "unprognostic (1.03e-1)" "unprognostic (4.50e-2)" "unprognostic (1.09e-1)" "prognostic favorable (5.01e-4)" "unprognostic (4.68e-3)" "unprognostic (4.66e-2)" "unprognostic (3.41e-2)" "unprognostic (7.55e-2)" "unprognostic (7.87e-3)" "unprognostic (3.25e-1)" "prognostic favorable (5.43e-4)" "unprognostic (1.51e-2)" "unprognostic (2.38e-1)" "unprognostic (1.24e-1)" "unprognostic (2.17e-2)" 32.3 48.6 28.9 20.4 28.4 28.1 34.9 27.9 36.4 38.7 32.8 42.8 29.1 32.8 7.8 37.7 38.2 12.8 53.6 29.2 27.4 46.6 44.9 34.4 26.0 29.1 28.1 34.5 34.2 20.4 51.5 14.7 28.0 50.3 8.1 36.4 35.9 17.3 33.5 38.7 45.1 9.2 27.0 57.1 41.4 36.7 28.8 20.3 45.7 15.5 11.6 37.5 35.6 28.1 25.0 52.4 25.6 39.7 13.1 13.7 44.7 41.7 19.2 33.9 26.2 70.3 37.1 29.5 28.8 16.6 11.8 47.3 17.7 39.6 8.7 41.9 77.2 32.5 65.5 52.2 24.7 29.9 44.2 21.3 29.5 25.0 14.2 17.9 24.5 35.9 62.6 22.1 17.3 108.2 33.1 32.5 67.3 21.5 33.5 72.6 30.5 59.1 20.6 48.8 57.7 70.1 39.2 50.6 22.8 11.0 49.6 46.4 38.9 25.4 41.7 23.5 30.8 56.0 40.0 38.6 17.9 28.3 39.6 5.5 19.5 21.8 22.9 23.0 13.9 11.6 18.3 18.4 19.4 12.1 13.7 11.7 16.8 12.0 18.4 20.3 23.0 17.6 28.9 28.4 27.9 36.4 29.2 27.4 29.1 28.1 28.0 27.0 28.8 28.1 30.1 32.1 27.5 53.2 37.1 33.8 26.8 80.0 25.6 98.6 29.6 25.8 25.7 30.0 38.3 29.5 264.8 63.2 46.7 63.3 21.5 40.2 6.3 16.5 21.7 26.6 43.0 17.1 46.5 35.8 52.1 26.5 51.0 21.9 51.4 40.6 20.0 34.7 35.8 85.8 36.2 52.2 61.1 30.3 29.8 7.5 27.1 26.0 28.4 20.6 45.2 40.1 46.4 17.1 27.3 43.8 46.8 25.6 23.7 25.0 47.3 24.3 27.9 284.9 52.6 19.9 31.5 44.5 51.4 19.3 31.7 67.0 42.1 45.5 54.2 23.3 RICTOR "AVO3, KIAA1999, MGC39830, PIA" ENSG00000164327 "RPTOR independent companion of MTOR complex 2" Q6R327 5 38937920-39074399 "Predicted intracellular proteins" "Host-virus interaction" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 258.9;Oligodendrocytes: 343.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 30.3" "Lineage enriched" "Detected in all" 5 "granulocytes: 30.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037802, HPA037803" Approved Approved Mitochondria NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 6: Brain - Smell perception" "Cluster 20: HeLa - Mitochondria" "Cluster 9: Photoreceptor cells - Phototransduction" Mitochondria "HPA037802: AB_10672286, HPA037803: AB_2675676" "unprognostic (2.25e-2)" "unprognostic (8.30e-2)" "unprognostic (4.02e-1)" "unprognostic (7.94e-3)" "unprognostic (5.47e-2)" "unprognostic (2.95e-3)" "unprognostic (2.95e-3)" "unprognostic (1.33e-1)" "unprognostic (3.55e-2)" "unprognostic (4.37e-1)" "unprognostic (2.73e-2)" "unprognostic (8.29e-2)" "unprognostic (2.41e-1)" "unprognostic (2.58e-1)" "unprognostic (3.42e-1)" "unprognostic (1.51e-1)" "unprognostic (1.64e-2)" 7.7 5.5 7.3 8.8 10.2 24.5 9.4 17.4 9.9 7.7 0.9 7.1 5.4 9.2 6.3 5.5 6.9 6.2 10.0 8.4 7.2 7.0 7.7 9.9 11.3 9.1 7.0 10.0 6.2 6.7 4.9 8.9 10.6 6.6 6.6 26.3 6.4 5.1 11.7 8.4 7.9 6.8 9.2 10.2 7.0 9.3 7.6 12.8 8.6 11.5 9.2 7.1 7.2 16.9 5.9 10.6 7.6 7.6 9.5 10.8 11.1 8.1 18.7 8.7 8.7 6.5 10.5 9.7 3.0 8.0 13.2 9.5 6.7 8.8 10.5 8.6 6.0 11.4 25.4 7.9 6.1 9.7 14.6 9.2 6.4 10.8 11.8 8.6 14.6 7.8 9.4 18.1 5.9 3.1 9.9 16.0 4.9 3.1 8.2 7.9 13.6 8.6 7.2 9.7 6.4 4.4 21.1 7.8 10.9 7.1 5.4 10.5 12.5 17.6 8.5 7.2 6.1 8.0 5.3 9.5 7.5 12.7 6.6 8.7 1.4 8.5 4.9 1.4 4.0 3.8 4.9 4.3 1.5 4.6 5.2 6.0 30.3 3.7 3.4 5.1 3.3 0.8 7.3 10.2 17.4 9.9 8.4 7.2 9.1 7.0 10.6 9.2 7.6 16.9 32.9 64.1 50.2 72.8 62.4 48.8 39.6 38.7 27.3 69.6 28.6 13.5 38.4 28.6 34.7 27.6 204.3 40.5 65.6 28.0 0.0 25.9 2.3 33.0 31.1 43.0 43.6 73.4 153.8 15.9 20.6 37.4 30.1 35.1 33.0 32.9 49.2 33.0 19.3 52.2 153.9 26.0 22.4 40.6 47.6 5.3 47.5 36.3 33.8 108.7 45.2 28.8 74.2 258.9 343.1 28.1 29.9 32.4 48.7 65.8 30.7 15.3 38.0 176.0 13.1 43.6 34.6 36.5 33.2 18.3 45.0 96.5 70.9 21.3 19.6 74.6 RMND1 "bA351K16.3, C6orf96, FLJ20627, RMD1" ENSG00000155906 "Required for meiotic nuclear division 1 homolog" Q9NWS8 6 151404762-151452158 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein biosynthesis" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031397, HPA031398, HPA031399" Approved Supported Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Mitochondria "HPA031397: AB_2673861, HPA031398: AB_2673862, HPA031399: AB_10601156" "unprognostic (1.12e-1)" "unprognostic (4.45e-2)" "unprognostic (9.70e-3)" "unprognostic (6.67e-2)" "unprognostic (2.65e-2)" "prognostic unfavorable (6.96e-4)" "unprognostic (1.50e-3)" "unprognostic (6.56e-2)" "unprognostic (1.02e-1)" "unprognostic (1.73e-1)" "unprognostic (2.03e-1)" "unprognostic (3.57e-1)" "unprognostic (1.47e-1)" "unprognostic (1.55e-1)" "unprognostic (1.80e-1)" "unprognostic (9.74e-2)" "unprognostic (1.04e-1)" 12.6 13.9 7.7 6.4 8.1 4.4 13.6 7.8 8.9 9.9 8.2 10.3 13.4 8.9 11.7 7.5 11.9 8.0 12.1 7.8 8.6 36.9 30.5 7.5 9.2 8.2 8.1 14.6 9.5 8.9 6.3 9.6 8.4 6.8 11.3 7.1 7.1 7.7 10.9 7.7 12.1 7.5 8.0 7.3 8.0 9.1 8.6 8.1 18.6 10.0 10.1 9.2 8.1 8.2 16.0 7.2 15.1 32.3 20.6 46.7 21.3 24.6 23.4 18.6 25.4 21.5 11.7 14.9 17.4 16.1 23.1 13.5 29.3 14.9 32.1 17.7 23.8 24.1 11.0 44.5 43.4 53.9 7.2 33.4 19.5 26.9 39.7 22.8 25.0 22.6 26.3 11.5 29.0 54.1 18.6 18.1 11.1 16.8 14.3 21.0 19.7 18.2 26.7 7.2 26.1 25.5 17.9 22.2 29.5 18.6 36.6 34.8 13.8 14.6 19.0 30.6 20.0 12.1 17.5 17.6 36.7 42.3 17.5 1.9 5.6 7.1 6.4 8.2 10.4 11.6 7.6 9.1 7.0 8.9 10.1 9.3 2.8 13.3 13.3 3.2 11.8 4.5 7.7 8.1 7.8 8.9 7.8 8.6 8.2 8.1 8.4 8.0 8.6 8.2 11.6 0.0 11.2 12.1 6.9 3.8 6.4 10.2 9.1 8.9 15.4 13.7 11.9 5.7 11.9 12.9 12.5 27.0 7.4 7.6 17.6 15.6 9.4 10.9 18.4 7.8 3.0 8.0 22.4 10.7 21.7 8.8 4.1 12.4 9.5 25.0 10.8 16.7 13.7 5.0 20.6 9.7 6.1 12.5 5.7 6.4 6.8 9.8 3.6 8.4 12.3 7.7 10.3 15.6 21.7 9.9 11.2 6.4 5.8 3.6 33.8 45.1 9.3 6.9 0.0 6.7 14.9 13.0 16.8 8.3 2.7 16.8 8.4 27.3 15.3 5.3 RNF138 "NARF, STRIN" ENSG00000134758 "Ring finger protein 138" Q8WVD3 18 32091874-32131561 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway, Wnt signaling pathway" "DNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 96.0;testis: 119.3" "Group enriched" "Detected in many" 15 "Early spermatids: 982.8;Late spermatids: 3827.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041101 Approved Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "HPA041101: AB_10805837" "unprognostic (2.37e-2)" "unprognostic (4.63e-3)" "unprognostic (2.03e-3)" "unprognostic (1.01e-1)" "unprognostic (2.34e-1)" "unprognostic (2.93e-2)" "unprognostic (1.47e-2)" "unprognostic (9.64e-2)" "unprognostic (1.29e-2)" "unprognostic (1.90e-2)" "unprognostic (6.90e-2)" "unprognostic (1.27e-2)" "unprognostic (6.15e-2)" "unprognostic (9.52e-3)" "unprognostic (2.77e-1)" "unprognostic (9.58e-2)" "unprognostic (1.90e-1)" 13.7 7.3 7.6 17.4 9.3 96.0 14.5 13.8 11.9 12.4 10.7 23.5 16.7 14.3 8.5 14.9 19.4 13.6 5.9 6.9 8.7 9.7 21.6 13.3 24.2 8.0 8.6 14.9 16.4 11.2 7.5 15.3 8.5 10.5 20.2 8.9 9.9 7.9 6.9 8.8 17.3 11.6 8.3 21.6 14.2 119.3 8.2 28.9 11.8 6.8 19.8 13.3 8.6 12.4 28.3 16.4 66.4 33.2 8.5 17.5 37.6 28.3 15.8 34.7 39.8 19.4 19.3 67.9 34.3 18.6 22.3 28.9 35.1 31.9 47.1 37.7 58.8 53.5 19.2 24.1 33.3 149.3 45.3 17.1 31.3 38.3 53.8 19.9 35.9 59.3 74.7 27.0 22.7 26.6 101.1 66.5 74.4 48.4 22.6 102.5 41.7 39.3 31.9 20.7 75.0 37.5 37.7 21.7 30.1 30.2 14.0 62.2 27.8 41.5 30.5 10.3 32.2 44.4 64.5 117.9 22.6 81.6 41.5 25.0 64.4 63.3 25.0 48.7 32.2 34.6 54.5 35.9 62.5 39.2 102.8 66.9 64.7 42.8 42.0 26.6 44.3 68.3 7.6 9.3 13.8 11.9 6.9 8.7 8.0 8.6 8.5 8.3 8.2 12.4 27.9 16.0 19.7 15.3 65.9 69.3 33.7 11.8 71.2 6.7 32.4 18.0 8.3 24.3 16.8 16.5 0.0 28.3 51.6 43.0 17.6 17.6 982.8 35.6 20.4 29.4 29.9 48.8 25.9 18.4 21.6 21.3 26.0 28.7 22.8 8.4 22.5 16.8 24.8 8.4 28.0 20.8 20.3 25.5 52.3 3827.9 29.5 34.7 26.6 23.4 27.1 9.9 20.6 22.6 36.4 12.9 23.9 22.2 32.4 32.7 16.4 14.5 23.0 5.2 32.9 23.1 26.0 158.1 128.3 51.4 52.1 8.9 59.3 9.9 29.9 37.5 RTP3 "LTM1, TMEM7, Z3CXXC3" ENSG00000163825 "Receptor transporter protein 3" Q9BQQ7 3 46497976-46500950 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 130 "liver: 119.5" "Cell type enriched" "Detected in some" 40 "Hepatocytes: 89.6" "Cancer enriched" "Detected in some" 5 "liver cancer: 22.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "SiHa: 12.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA075932 Uncertain Mitochondria NA NA "Cluster 62: Liver - Hemostasis" "Cluster 20: HeLa - Mitochondria" "Cluster 2: Hepatocytes - Metabolism" Mitochondria "HPA075932: " "unprognostic (2.09e-1)" "unprognostic (1.64e-1)" "prognostic favorable (3.11e-6)" "unprognostic (1.08e-1)" "unprognostic (1.58e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.6 119.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 12.5 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.2 89.6 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 1.4 1.9 0.0 0.0 0.0 0.1 0.1 0.0 0.0 S100A10 "42C, ANX2LG, CAL1L, CLP11, P11" ENSG00000197747 "S100 calcium binding protein A10" P60903 1 151982915-151993859 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 1760.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 3820.4;Langerhans cells: 3945.6;Pancreatic endocrine cells: 4570.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 2005.4;monocytes: 1235.2;T-cells: 1180.0" "Cell line enhanced" "Detected in all" "OE19: 4936.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003340, CAB025484" Enhanced Approved Mitochondria Yes No 270000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" Mitochondria "CAB025484: , HPA003340: AB_1856531" "unprognostic (2.13e-1)" "unprognostic (1.51e-3)" "unprognostic (1.01e-1)" "unprognostic (3.15e-1)" "unprognostic (6.20e-2)" "prognostic unfavorable (3.33e-4)" "prognostic unfavorable (1.00e-4)" "prognostic unfavorable (2.66e-5)" "unprognostic (1.09e-2)" "unprognostic (9.48e-2)" "prognostic unfavorable (3.88e-4)" "unprognostic (1.36e-1)" "prognostic unfavorable (3.80e-8)" "unprognostic (1.09e-1)" "unprognostic (1.50e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (3.84e-4)" 775.1 376.9 71.1 244.8 76.6 133.7 519.6 75.5 139.8 478.0 78.5 867.3 461.4 110.1 56.7 1760.5 188.7 212.4 340.9 72.4 132.8 735.0 157.7 689.8 133.3 148.2 105.0 234.0 145.0 36.3 71.0 326.9 108.5 164.9 924.2 51.3 422.8 105.0 106.0 483.4 448.0 288.2 98.2 111.2 189.1 145.8 138.8 118.3 143.5 145.4 289.8 338.4 803.1 110.3 1251.3 1085.9 3.4 241.6 1351.4 1711.3 972.5 730.1 912.1 613.8 606.5 1975.4 1671.4 2.3 689.1 1208.0 661.7 2227.5 337.0 2786.6 495.3 242.5 127.1 163.8 461.5 468.1 507.0 60.2 126.7 470.8 2195.5 660.6 738.6 487.6 1326.0 78.9 2.9 3.6 753.8 940.0 11.0 376.5 163.6 4936.7 1671.4 1.6 242.4 27.1 2348.3 317.0 11.1 9.5 1259.2 374.3 539.8 1213.0 882.2 130.5 1654.9 285.5 737.2 1362.3 459.2 34.4 7.8 225.2 1709.5 51.7 977.8 359.5 1235.2 299.7 425.7 758.7 443.3 232.4 652.3 539.0 2005.4 140.1 237.7 363.1 43.6 355.0 664.7 329.6 1180.0 1313.4 71.1 76.6 75.5 139.8 72.4 132.8 148.2 105.0 108.5 98.2 138.8 110.3 1197.3 2554.5 537.7 3.9 244.0 1594.8 1171.4 2183.2 795.6 11.6 241.1 281.4 111.2 693.4 994.6 950.9 4.2 1271.5 476.2 3820.4 1524.1 1811.7 314.2 901.0 104.6 1061.2 1078.1 114.2 0.4 2105.0 527.4 1751.3 432.8 1270.7 289.5 840.0 864.5 206.9 1023.1 16.8 0.9 1723.1 272.6 795.2 3945.6 274.2 647.1 1338.1 1632.8 28.1 1544.2 24.8 285.3 4.0 0.6 4570.5 3391.8 64.7 244.5 2782.5 2146.1 495.6 620.3 32.5 144.7 801.6 529.5 30.4 115.9 1940.1 1242.0 375.8 801.0 38.5 1998.0 2290.6 S1PR4 EDG6 ENSG00000125910 "Sphingosine-1-phosphate receptor 4" O95977 19 3172346-3180332 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.6;lymphoid tissue: 61.1" "Cell type enhanced" "Detected in some" "B-cells: 62.3;dendritic cells: 76.7;monocytes: 33.7;NK-cells: 140.1;T-cells: 64.0" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "cerebral cortex: 2.4" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 24.0;HL-60: 32.2;NB-4: 31.7;REH: 89.2;U-937: 30.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA060601, HPA067232" Supported Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 14: REH - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" Mitochondria "HPA060601: AB_2797261, HPA067232: AB_2797271" "prognostic favorable (3.13e-4)" "prognostic favorable (1.33e-4)" "unprognostic (2.58e-2)" "prognostic favorable (2.22e-4)" "unprognostic (2.98e-2)" "prognostic favorable (1.45e-6)" "unprognostic (1.27e-2)" "unprognostic (8.73e-2)" "unprognostic (1.21e-3)" "unprognostic (6.64e-3)" "unprognostic (3.59e-1)" "unprognostic (2.20e-1)" "prognostic unfavorable (2.87e-4)" "unprognostic (2.97e-1)" "unprognostic (1.12e-1)" "unprognostic (2.06e-1)" "unprognostic (6.15e-3)" 4.6 1.0 0.3 10.7 0.2 19.6 2.8 0.1 2.4 1.0 0.2 2.3 1.1 0.9 0.0 2.3 2.3 1.0 1.6 0.2 0.1 1.7 1.6 11.9 16.5 0.3 0.1 0.3 0.7 0.1 0.3 1.4 0.6 1.3 0.2 0.0 1.2 0.1 0.6 0.8 13.6 0.5 0.2 61.1 4.9 0.2 0.5 4.8 2.9 0.7 4.8 2.8 1.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 10.9 0.3 0.0 0.0 0.3 0.0 0.1 0.0 24.0 0.0 10.2 0.2 0.0 0.0 32.2 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 31.7 0.0 0.3 0.0 89.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.1 0.0 0.3 0.0 0.0 0.1 0.0 3.5 0.0 30.4 0.0 53.2 28.3 81.0 31.1 32.5 27.2 32.3 37.9 29.9 20.4 39.3 31.6 30.2 120.8 16.3 44.7 18.1 67.6 21.6 0.3 0.2 0.1 2.4 0.2 0.1 0.3 0.1 0.6 0.2 0.5 0.1 6.3 3.2 4.6 0.0 62.3 1.3 0.2 0.8 0.0 0.0 0.4 0.3 0.4 1.5 1.9 1.8 0.0 0.2 76.7 0.2 0.0 0.1 0.1 0.4 0.1 4.1 0.0 17.0 0.0 0.2 0.2 0.5 3.1 0.3 5.7 0.0 6.8 0.8 25.2 0.0 0.0 0.0 0.0 27.6 8.3 0.0 0.0 27.8 1.8 0.0 33.7 0.0 140.1 0.0 0.0 0.1 0.0 0.0 27.7 0.3 0.0 0.3 2.7 0.0 0.0 0.5 0.3 0.0 0.0 0.1 1.4 0.0 64.0 0.0 0.0 0.6 SAMD13 ENSG00000203943 "Sterile alpha motif domain containing 13" Q5VXD3 1 84298366-84389957 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.5;choroid plexus: 26.9;intestine: 22.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 20.3;Intestinal goblet cells: 18.0;Oligodendrocytes: 16.4;Paneth cells: 33.2;Spermatocytes: 22.5;Undifferentiated cells: 21.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 15 "basophil: 12.5" "Lineage enriched" "Detected in single" 15 "granulocytes: 12.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA058929 Enhanced Approved Mitochondria NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA058929: AB_2683855" "unprognostic (3.78e-2)" "unprognostic (4.93e-2)" "unprognostic (8.51e-3)" "unprognostic (7.55e-2)" "prognostic favorable (1.14e-8)" "unprognostic (1.78e-1)" "unprognostic (1.65e-6)" "unprognostic (2.05e-1)" "unprognostic (5.50e-2)" "unprognostic (2.80e-3)" "unprognostic (9.42e-2)" "unprognostic (3.29e-1)" "unprognostic (1.98e-7)" "unprognostic (3.99e-2)" "unprognostic (1.81e-1)" "unprognostic (1.17e-1)" "unprognostic (7.56e-3)" 0.9 3.4 22.3 1.5 30.7 2.8 2.4 11.3 25.7 1.6 26.9 19.5 3.4 1.7 4.1 0.8 4.1 1.8 2.4 19.6 29.0 1.4 0.4 0.9 1.2 29.0 29.4 0.3 1.8 1.2 1.0 0.8 27.7 4.0 22.0 0.8 17.6 2.1 6.2 1.2 3.8 2.5 29.9 1.1 6.1 13.1 35.5 2.8 9.8 3.0 0.6 1.8 0.4 32.5 0.5 2.3 1.1 3.5 3.6 3.3 2.3 0.3 0.2 0.3 0.2 0.0 3.4 3.6 6.3 0.1 0.7 0.4 0.4 1.2 0.5 2.0 1.7 1.3 1.7 0.3 0.8 4.4 0.0 1.3 1.6 0.1 1.0 2.5 8.2 7.8 0.5 1.1 1.0 1.1 5.1 0.5 3.5 2.9 2.3 0.5 2.5 1.5 6.5 2.1 1.4 5.1 0.1 0.1 8.1 1.4 1.0 4.1 1.4 1.4 0.3 0.3 1.0 2.4 0.5 6.3 0.3 3.8 1.1 12.5 0.3 0.0 0.0 0.5 0.2 0.2 0.0 0.0 0.7 0.7 0.3 0.4 0.1 0.5 0.3 0.8 0.0 0.3 22.3 30.7 11.3 25.7 19.6 29.0 29.0 29.4 27.7 29.9 35.5 32.5 1.7 0.0 0.6 2.0 0.3 0.4 0.7 0.7 0.6 1.2 3.8 2.9 1.0 2.8 1.1 1.8 0.0 4.5 0.1 20.3 5.9 2.1 5.6 5.4 1.6 1.6 11.4 6.1 5.2 0.6 0.6 1.4 3.6 4.7 5.7 2.0 3.3 0.1 1.5 0.0 5.8 18.0 0.0 2.4 1.6 5.8 1.8 1.4 8.8 6.5 0.4 2.7 0.0 7.1 16.4 1.1 33.2 2.6 0.1 2.0 3.8 2.9 1.1 0.1 0.0 1.8 0.7 22.5 5.5 2.2 0.3 0.8 0.7 4.1 21.3 1.2 SAMM50 "CGI-51, OMP85, SAM50, TOB55, TRG-3, YNL026W" ENSG00000100347 "SAMM50 sorting and assembly machinery component" Q9Y512 22 43955442-44010531 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 240.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034537 Enhanced Supported Mitochondria NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA034537: AB_10602794" "unprognostic (2.92e-1)" "unprognostic (1.01e-1)" "unprognostic (1.95e-3)" "prognostic favorable (2.63e-7)" "unprognostic (2.43e-3)" "unprognostic (2.28e-1)" "unprognostic (5.28e-3)" "unprognostic (1.70e-3)" "unprognostic (3.37e-2)" "unprognostic (1.95e-1)" "unprognostic (2.42e-1)" "unprognostic (3.52e-1)" "prognostic favorable (4.43e-8)" "unprognostic (1.08e-1)" "unprognostic (1.51e-1)" "unprognostic (2.41e-1)" "unprognostic (1.60e-1)" 41.7 50.6 26.1 27.0 27.0 32.5 35.8 29.8 30.6 43.4 31.1 35.6 50.8 27.0 29.3 31.7 41.9 29.3 65.5 27.1 29.2 48.8 37.2 22.2 34.6 29.8 28.5 40.0 33.3 114.4 24.4 20.1 30.4 26.5 35.5 25.5 35.2 25.1 240.4 35.9 38.3 27.7 27.0 24.4 43.8 26.1 28.5 34.4 28.1 177.0 37.0 27.9 24.0 28.0 64.6 59.8 57.1 69.5 72.2 75.9 79.8 61.7 65.7 89.1 76.4 86.1 46.0 105.9 44.3 70.8 51.4 75.6 85.4 82.6 79.7 29.4 105.3 57.5 73.9 102.6 50.4 184.0 83.1 88.3 64.7 77.0 35.5 62.3 93.1 49.9 49.9 34.0 80.9 91.7 72.6 72.0 56.0 77.4 70.9 83.8 61.8 85.9 74.4 81.0 34.1 55.4 68.3 72.2 104.1 60.4 67.7 59.8 57.7 57.3 68.8 53.6 51.2 50.1 74.4 82.1 72.0 66.3 58.7 47.5 39.2 46.9 39.8 39.0 55.4 55.1 36.6 40.5 67.7 51.0 37.8 36.0 6.1 39.1 31.8 26.7 45.7 40.2 26.1 27.0 29.8 30.6 27.1 29.2 29.8 28.5 30.4 27.0 28.5 28.0 52.9 35.3 18.9 10.4 31.6 20.6 27.0 72.0 30.7 20.1 32.1 40.9 68.6 18.6 39.5 9.2 8.4 41.6 31.7 36.1 60.7 47.2 40.3 47.3 24.9 35.1 18.6 51.4 12.0 55.5 54.1 24.6 42.3 32.7 27.3 43.9 30.0 41.8 51.1 32.0 12.7 35.2 46.8 28.6 20.5 50.1 26.1 25.0 16.0 12.2 41.4 32.8 33.0 9.5 9.1 43.7 34.5 30.5 31.0 16.2 82.4 116.8 39.9 30.1 19.7 23.2 33.4 45.8 31.2 34.3 22.6 20.5 28.5 69.9 59.8 19.3 SARDH "DMGDHL1, SDH" ENSG00000123453 "Sarcosine dehydrogenase" Q9UL12 9 133663560-133739955 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "epididymis: 47.9;liver: 114.4;pancreas: 43.2" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 120.6" "Cancer enriched" "Detected in many" 8 "liver cancer: 18.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "memory CD4 T-cell: 3.3;naive CD4 T-cell: 6.7;T-reg: 8.8" "Lineage enriched" "Detected in single" 16 "T-cells: 8.8" "Cell line enhanced" "Detected in many" "AN3-CA: 17.4;Hep G2: 31.1;MOLT-4: 22.5;RH-30: 18.5;RPMI-8226: 39.1;SH-SY5Y: 14.7" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA057267, HPA058086" Approved Approved Mitochondria NA NA 230000 "Cluster 20: T-cells - T-cell receptor" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA057267: AB_2683388, HPA058086: AB_2683601" "unprognostic (3.64e-2)" "unprognostic (4.87e-2)" "unprognostic (2.31e-2)" "unprognostic (1.38e-1)" "prognostic unfavorable (4.62e-4)" "unprognostic (5.83e-2)" "unprognostic (1.42e-3)" "unprognostic (2.21e-1)" "unprognostic (1.58e-1)" "unprognostic (1.43e-1)" "unprognostic (2.23e-1)" "unprognostic (1.74e-1)" "unprognostic (7.74e-3)" "unprognostic (2.78e-1)" "unprognostic (3.48e-1)" "unprognostic (9.73e-2)" "unprognostic (1.30e-2)" 1.1 2.2 3.6 2.5 3.5 0.9 0.8 1.9 3.9 2.6 0.7 1.1 1.8 2.0 47.9 0.6 1.9 1.3 2.4 3.3 3.5 12.0 114.4 2.6 4.1 4.4 3.1 3.0 43.2 2.1 4.1 0.9 3.4 2.3 0.4 0.6 5.3 1.8 0.6 0.4 1.3 0.9 2.9 1.3 3.0 0.7 4.2 4.3 1.6 0.3 2.4 1.1 1.0 3.1 0.0 0.1 1.4 17.4 0.1 0.5 2.3 0.1 0.7 0.9 1.1 0.3 0.2 0.0 2.4 0.3 2.2 0.1 0.0 0.3 0.7 0.0 0.3 2.5 0.0 31.1 1.9 0.1 0.3 4.2 0.0 2.0 0.1 0.4 0.2 13.1 0.1 0.4 11.1 3.2 22.5 2.4 2.8 1.7 0.2 1.6 18.5 39.1 0.0 0.1 1.7 14.7 0.0 0.4 3.9 0.8 2.4 0.2 0.1 3.3 3.0 0.3 0.0 0.3 0.0 1.3 2.1 1.4 0.1 0.3 0.1 0.1 0.3 0.0 0.8 0.0 3.3 0.8 0.0 0.3 6.7 1.2 0.5 0.1 0.0 0.3 8.8 1.4 3.6 3.5 1.9 3.9 3.3 3.5 4.4 3.1 3.4 2.9 4.2 3.1 0.1 0.0 1.9 6.8 0.4 0.3 0.4 0.0 1.2 0.1 0.2 0.8 0.8 0.0 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 1.0 0.8 1.2 5.7 1.5 1.1 0.1 2.3 0.0 0.3 1.3 0.8 2.9 120.6 0.1 0.0 0.7 0.0 0.0 1.6 0.6 0.8 4.7 0.2 0.0 1.9 0.0 4.2 1.0 0.5 0.3 0.1 0.0 3.0 0.7 0.3 0.0 21.3 0.0 0.3 0.0 1.6 3.5 0.1 0.8 0.0 0.1 0.0 4.2 1.6 0.0 0.2 SARM1 "KIAA0524, SAMD2, SARM" ENSG00000004139 "Sterile alpha and TIR motif containing 1" Q6SZW1 17 28364356-28404049 "Enzymes, Predicted intracellular proteins" "Differentiation, Immunity, Innate immunity, Neurogenesis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 27.8;Cone photoreceptor cells: 29.2;Inhibitory neurons: 28.9;Oligodendrocyte precursor cells: 27.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 32.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024359, HPA024759" Uncertain Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 56: Bipolar cells - Visual perception" Mitochondria "HPA024359: AB_1856582, HPA024759: AB_1856581" "unprognostic (1.40e-4)" "unprognostic (9.00e-2)" "unprognostic (2.47e-1)" "unprognostic (2.41e-2)" "unprognostic (1.18e-1)" "unprognostic (1.08e-2)" "unprognostic (1.27e-1)" "unprognostic (1.27e-2)" "unprognostic (1.87e-2)" "unprognostic (7.01e-2)" "unprognostic (2.49e-4)" "unprognostic (6.40e-2)" "unprognostic (5.20e-2)" "unprognostic (1.20e-1)" "unprognostic (2.14e-1)" "unprognostic (4.84e-2)" "unprognostic (7.62e-4)" 2.2 5.9 3.9 3.3 3.6 1.4 2.1 7.3 4.2 3.1 1.6 3.3 7.5 4.0 4.0 1.4 3.6 1.5 1.8 3.9 3.1 2.7 3.4 2.0 2.0 3.3 2.7 2.8 7.1 2.6 6.1 1.2 3.2 3.5 2.2 7.0 2.6 4.2 1.5 2.3 5.2 3.5 2.4 4.4 3.3 1.3 3.6 1.1 2.8 1.0 2.1 3.8 1.9 2.8 0.2 3.0 3.8 4.8 2.7 1.9 0.6 2.1 4.1 4.4 2.9 32.2 0.5 0.6 0.2 3.0 2.6 1.3 2.7 0.1 3.7 7.0 1.8 0.0 5.5 0.8 2.0 0.1 1.9 1.3 0.2 2.1 0.6 4.2 0.2 0.9 0.1 2.4 1.2 2.8 0.4 0.0 2.6 0.6 0.2 1.1 3.2 0.8 1.4 2.2 9.9 9.2 9.2 1.3 3.5 1.6 0.4 0.7 0.4 4.0 0.4 1.4 2.9 4.0 2.9 0.6 4.2 0.3 2.0 0.1 0.1 0.0 0.2 0.2 0.2 0.1 0.3 0.3 0.2 0.2 0.2 0.3 0.1 0.3 0.5 0.0 0.4 0.1 3.9 3.6 7.3 4.2 3.9 3.1 3.3 2.7 3.2 2.4 3.6 2.8 2.7 3.2 4.2 19.6 4.0 0.9 1.8 1.2 4.6 27.8 3.1 4.2 0.8 7.2 4.8 3.7 29.2 0.6 2.9 3.0 3.9 4.4 6.6 3.8 5.4 2.9 9.5 0.4 23.5 10.7 0.8 3.5 8.2 3.7 4.5 6.1 3.6 2.3 1.5 21.9 28.9 4.1 2.0 13.8 0.3 3.5 3.4 2.8 3.6 2.8 2.4 6.1 3.1 27.6 14.8 3.4 2.3 1.5 2.6 2.3 9.9 5.9 4.3 17.2 6.6 5.9 4.0 0.3 0.4 3.1 0.6 0.5 4.7 2.0 4.9 1.4 SBK3 SgK110 ENSG00000231274 "SH3 domain binding kinase family member 3" P0C264 19 55540656-55545543 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 32.5;tongue: 15.1" "Cell type enriched" "Detected in single" 5 "Cardiomyocytes: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 5.0;CACO-2: 1.8;CAPAN-2: 2.9;K-562: 1.2;NTERA-2: 1.3;RH-30: 2.2" "Not detected" "Not detected" HPA078322 Approved Mitochondria NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 43: Cardiomyocytes - Nuclear processes" Mitochondria "HPA078322: AB_2732379" "unprognostic (2.15e-1)" "unprognostic (1.99e-3)" "unprognostic (2.71e-1)" "unprognostic (1.39e-3)" "unprognostic (7.52e-2)" "unprognostic (2.83e-1)" "unprognostic (5.47e-5)" "unprognostic (4.64e-3)" "unprognostic (7.24e-2)" "unprognostic (1.65e-1)" "unprognostic (3.38e-1)" "unprognostic (3.08e-3)" "unprognostic (1.21e-2)" "unprognostic (4.92e-2)" "unprognostic (2.41e-1)" "unprognostic (1.79e-1)" 2.5 0.0 0.0 0.1 0.0 0.0 1.0 0.4 0.0 0.3 0.0 0.1 0.4 0.2 0.0 2.0 0.2 0.3 32.5 0.0 0.0 0.4 0.1 0.5 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.0 0.3 0.2 0.0 0.0 0.5 0.0 6.5 0.2 0.2 0.2 0.1 0.0 0.4 0.2 0.1 0.0 0.5 15.1 0.0 0.3 0.1 0.1 0.0 5.0 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 1.8 2.9 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.5 0.0 0.0 1.3 0.0 0.3 0.1 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SCO2 "MYP6, SCO1L" ENSG00000284194 "Synthesis of cytochrome C oxidase 2" O43819 22 50523568-50526461 "Disease related genes, Human disease related genes, Predicted membrane proteins" Chaperone "Cardiomyopathy, Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 112.2;Paneth cells: 131.5;Proximal enterocytes: 110.7;Suprabasal keratinocytes: 98.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046943, HPA056254" Uncertain Approved Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA046943: AB_2732536, HPA056254: AB_2683080" 16.8 10.3 14.0 13.4 13.8 36.5 7.8 14.4 16.8 6.8 18.2 22.0 25.6 3.6 4.7 12.3 15.8 7.7 10.3 14.3 14.4 8.1 18.4 14.4 9.1 18.8 19.1 1.8 11.5 7.2 1.5 8.3 17.5 5.1 10.5 0.1 21.3 6.7 10.2 11.0 19.7 12.7 16.4 11.4 10.2 4.1 17.4 11.2 2.3 10.1 10.3 13.0 2.5 17.4 37.4 29.9 1.3 12.5 17.7 24.2 18.7 19.5 24.1 38.0 32.8 35.3 17.8 42.7 19.7 22.6 9.6 36.0 19.3 31.5 6.1 7.6 82.5 13.8 20.2 46.7 44.6 43.8 18.3 38.4 48.6 19.4 15.8 10.6 24.4 5.8 15.6 32.9 16.8 55.7 13.3 76.5 11.0 15.5 54.8 26.1 7.5 65.0 29.6 21.3 16.6 23.7 24.4 70.7 63.5 1.3 26.1 24.7 25.8 16.3 22.6 30.2 22.2 26.1 15.6 29.2 35.7 28.7 14.5 19.1 21.8 12.2 43.9 19.9 42.2 40.1 38.9 44.1 34.9 33.4 29.2 32.6 21.6 27.7 21.1 56.2 37.0 37.7 14.0 13.8 14.4 16.8 14.3 14.4 18.8 19.1 17.5 16.4 17.4 17.4 0.0 3.2 2.7 2.9 20.0 85.7 21.6 75.5 44.3 7.3 0.1 0.0 16.8 21.5 31.4 0.0 2.1 0.0 5.3 112.2 0.0 0.0 15.1 0.1 0.2 13.8 25.8 14.1 2.7 0.0 0.0 14.1 24.5 0.1 15.9 0.0 18.2 53.5 0.0 11.8 2.7 63.2 48.8 28.2 63.6 25.6 16.4 29.2 42.7 5.6 47.3 5.5 25.7 5.5 1.4 0.1 131.5 10.9 32.1 40.0 110.7 0.1 42.6 7.1 0.0 30.4 29.5 17.3 35.7 56.1 98.9 0.0 14.9 0.1 90.7 22.3 SDHAF1 LYRM8 ENSG00000205138 "Succinate dehydrogenase complex assembly factor 1" A6NFY7 19 35995188-35996312 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064277, HPA074563" Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 32: Non-specific - Translation" Mitochondria "HPA064277: AB_2685231, HPA074563: " "unprognostic (2.01e-1)" "unprognostic (3.46e-2)" "unprognostic (2.22e-2)" "unprognostic (3.11e-2)" "unprognostic (1.81e-1)" "unprognostic (4.47e-2)" "unprognostic (5.25e-2)" "unprognostic (2.29e-2)" "unprognostic (1.24e-1)" "unprognostic (3.78e-2)" "unprognostic (6.89e-3)" "unprognostic (1.83e-2)" "prognostic favorable (2.11e-4)" "unprognostic (1.38e-2)" "unprognostic (2.59e-1)" "unprognostic (2.24e-1)" "unprognostic (3.59e-2)" 15.4 16.2 13.7 6.3 15.2 4.2 16.1 17.8 15.5 19.1 13.3 21.5 13.6 16.3 6.1 16.3 17.0 4.8 15.0 14.1 14.4 18.5 32.7 12.8 9.5 16.0 14.4 15.0 24.7 9.6 20.1 5.5 16.3 16.5 5.0 6.8 16.9 6.6 19.0 18.3 18.9 3.0 15.4 19.1 18.9 9.9 14.5 8.5 16.4 7.6 6.0 18.7 16.6 18.4 9.6 24.7 7.2 16.7 6.9 8.7 12.5 9.2 9.8 9.8 11.3 17.8 7.1 17.8 17.3 6.1 6.7 9.5 9.5 5.1 4.7 33.6 22.3 7.9 10.7 23.6 8.4 9.5 12.5 7.7 16.4 6.0 6.4 3.9 5.5 18.5 24.6 18.9 4.3 23.5 18.2 18.6 11.2 31.4 11.8 19.6 8.0 20.3 9.7 12.2 28.2 21.1 14.8 23.9 16.5 5.9 13.7 15.9 7.3 11.2 16.8 10.7 14.2 25.4 12.6 21.0 9.8 18.1 10.1 45.6 34.0 55.2 40.3 40.7 43.8 43.0 43.4 39.5 35.8 46.5 47.8 40.5 19.2 57.7 45.7 45.0 49.6 32.1 13.7 15.2 17.8 15.5 14.1 14.4 16.0 14.4 16.3 15.4 14.5 18.4 18.7 6.4 4.1 4.6 24.6 30.0 11.4 9.7 14.2 20.9 27.1 26.4 9.5 17.2 5.9 18.4 6.2 25.1 19.9 21.7 27.4 21.9 25.0 7.9 15.8 16.9 28.8 8.8 4.0 29.6 37.7 20.0 16.3 7.3 4.5 17.3 19.6 19.9 22.7 18.5 4.6 32.7 10.2 19.6 18.5 6.5 23.0 12.1 24.9 3.7 28.2 16.6 32.0 3.0 8.1 22.9 37.2 29.3 16.8 23.1 54.1 32.8 3.3 14.8 26.3 10.9 13.8 10.5 13.9 16.1 41.6 23.1 20.1 25.4 32.0 16.4 SDHAF3 "ACN9, DC11, LYRM10, Sdh7" ENSG00000196636 "Succinate dehydrogenase complex assembly factor 3" Q9NRP4 7 97117698-97181763 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 148.7;Early spermatids: 136.0;Proximal tubular cells: 150.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA020515, HPA020523" Approved Approved Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA020515: , HPA020523: AB_2670464" "unprognostic (3.94e-2)" "unprognostic (9.11e-2)" "unprognostic (6.51e-2)" "unprognostic (2.51e-2)" "unprognostic (1.39e-1)" "unprognostic (1.61e-2)" "unprognostic (9.60e-3)" "unprognostic (3.21e-2)" "unprognostic (3.74e-2)" "unprognostic (3.07e-3)" "unprognostic (4.27e-2)" "unprognostic (1.10e-1)" "unprognostic (7.67e-3)" "unprognostic (2.82e-1)" "unprognostic (3.79e-3)" "unprognostic (2.34e-1)" "unprognostic (8.45e-2)" 12.4 17.5 9.3 12.4 9.8 16.7 18.7 10.5 13.3 15.0 13.5 20.7 19.9 12.4 22.2 15.0 14.6 13.0 27.0 9.4 11.2 33.5 32.1 8.4 18.5 10.6 10.4 10.7 18.4 12.2 3.6 9.6 11.0 14.8 20.3 16.4 22.0 12.0 29.0 14.1 17.4 12.2 11.6 11.2 18.3 14.5 10.2 24.5 19.0 25.6 14.5 12.8 3.7 12.1 36.6 27.6 24.5 82.3 15.8 12.8 14.8 15.8 7.6 15.6 22.8 5.0 30.7 57.4 40.1 14.1 20.7 13.4 49.6 38.8 33.7 44.2 59.6 34.6 24.8 54.8 23.8 89.4 16.0 24.3 30.3 25.7 32.0 11.6 14.5 57.2 99.5 1.6 34.8 0.0 94.5 126.7 37.3 74.1 34.6 21.0 14.0 83.7 26.0 24.9 63.8 40.7 38.5 47.9 55.5 33.9 0.4 31.6 16.0 4.2 53.2 88.6 10.7 41.4 87.0 139.5 14.6 144.7 51.9 30.0 21.4 8.0 26.5 26.3 36.3 36.3 33.3 39.1 27.9 32.1 45.9 44.4 20.2 23.9 26.7 82.6 33.2 37.9 9.3 9.8 10.5 13.3 9.4 11.2 10.6 10.4 11.0 11.6 10.2 12.1 24.4 19.2 12.5 8.5 34.4 0.0 23.1 0.0 29.0 13.8 38.6 44.4 37.9 18.6 6.8 25.8 4.2 35.2 31.3 7.2 148.7 30.6 136.0 31.3 20.6 17.3 13.3 32.6 16.6 39.1 30.0 20.1 29.0 21.4 5.1 22.2 16.4 55.9 31.1 10.1 14.3 24.2 0.0 20.1 0.0 20.7 22.7 20.2 0.0 9.4 13.9 44.8 36.0 14.6 18.5 24.0 29.1 24.8 30.9 17.0 35.1 150.9 16.0 19.5 32.9 19.5 20.4 32.7 49.3 53.5 0.0 9.6 26.3 45.6 39.8 25.0 SETD3 "C14orf154, FLJ23027" ENSG00000183576 "SET domain containing 3, actin histidine methyltransferase" Q86TU7 14 99397748-99480889 "Enzymes, Predicted intracellular proteins" "Actin-binding, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 206.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003591, HPA003639" Approved Approved Mitochondria NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "HPA003591: AB_1079930, HPA003639: AB_1079931" "unprognostic (6.82e-2)" "unprognostic (2.66e-2)" "unprognostic (8.07e-2)" "unprognostic (2.16e-2)" "unprognostic (2.42e-1)" "prognostic unfavorable (6.46e-4)" "unprognostic (1.04e-2)" "unprognostic (3.24e-2)" "unprognostic (3.29e-1)" "unprognostic (2.73e-2)" "unprognostic (2.01e-1)" "unprognostic (4.42e-1)" "prognostic favorable (1.89e-15)" "unprognostic (6.81e-2)" "unprognostic (3.21e-1)" "unprognostic (2.20e-1)" "unprognostic (2.62e-3)" 38.8 26.6 49.6 25.2 50.6 23.5 30.1 46.9 59.2 29.2 45.1 49.5 36.3 26.2 83.5 36.6 46.6 29.4 79.0 48.1 47.8 96.1 47.2 37.4 24.1 46.4 45.5 22.0 37.6 40.1 21.6 42.6 45.9 35.9 37.9 64.5 57.8 41.6 174.0 31.6 37.4 39.4 46.2 28.4 29.1 85.0 52.2 24.5 53.4 118.2 24.8 36.3 24.4 52.1 39.9 44.6 33.1 31.7 37.6 42.0 117.1 49.4 37.4 50.3 51.1 43.5 65.7 38.8 39.5 55.6 39.5 50.4 40.8 55.2 79.6 38.5 22.0 35.3 27.8 40.2 46.9 53.6 51.2 29.6 71.3 44.7 64.8 37.9 63.4 57.2 28.3 56.9 56.3 74.7 56.6 57.9 19.9 98.5 50.7 34.1 67.8 32.0 72.6 48.4 58.9 27.4 44.3 45.4 38.4 59.7 61.6 46.2 56.6 22.6 31.5 153.8 38.2 40.6 49.3 42.1 42.6 52.5 35.3 7.6 18.1 24.9 17.7 21.5 20.6 11.4 15.0 16.6 22.4 8.9 12.3 15.4 10.8 20.6 19.2 14.1 12.2 14.8 49.6 50.6 46.9 59.2 48.1 47.8 46.4 45.5 45.9 46.2 52.2 52.1 31.1 25.6 44.5 43.1 16.9 24.3 18.6 14.4 21.6 26.0 22.8 17.1 83.0 18.6 24.8 25.8 27.1 61.9 37.3 37.2 33.2 24.7 206.6 29.9 24.9 29.1 21.7 11.3 47.7 28.0 45.4 22.2 17.3 30.7 32.9 7.5 22.9 27.5 35.8 18.5 43.6 28.2 14.2 29.7 23.2 121.0 19.0 35.9 10.6 52.5 27.9 47.6 60.8 38.2 36.8 25.7 20.3 21.1 23.6 26.1 30.1 101.5 28.1 39.5 6.6 25.3 23.0 130.4 73.0 25.0 32.4 30.0 27.9 9.2 30.5 20.8 SFXN1 "FLJ12876, SLC56A1" ENSG00000164466 "Sideroflexin 1" Q9H9B4 5 175477062-175529742 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, One-carbon metabolism, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 99.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 99.8" "Group enriched" "Detected in all" 5 "granulocytes: 99.8;T-cells: 36.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019543, HPA063745" Approved Enhanced Mitochondria NA NA 23000 "Cluster 46: Basophils - DNA binding" "Cluster 85: Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 58: T-cells - T-cell receptor" Mitochondria "HPA019543: AB_1856789, HPA063745: AB_2685111" "unprognostic (4.77e-3)" "unprognostic (5.26e-2)" "unprognostic (1.54e-2)" "unprognostic (3.62e-3)" "unprognostic (2.35e-1)" "unprognostic (1.30e-2)" "unprognostic (3.59e-2)" "unprognostic (8.58e-3)" "unprognostic (2.47e-2)" "unprognostic (1.17e-2)" "unprognostic (2.48e-2)" "unprognostic (1.51e-1)" "unprognostic (1.31e-1)" "unprognostic (7.30e-2)" "unprognostic (4.98e-1)" "unprognostic (1.08e-3)" "unprognostic (4.23e-2)" 7.6 15.4 14.0 18.2 14.8 21.9 8.1 15.0 17.4 9.3 15.0 28.1 19.3 8.5 8.0 14.7 8.7 9.8 12.3 13.3 15.3 41.6 99.7 5.9 27.0 12.1 12.6 18.7 13.1 15.8 12.9 15.3 13.2 9.6 17.7 20.7 9.6 10.4 10.9 8.8 20.1 11.3 13.0 10.5 14.6 6.6 13.8 24.0 10.5 15.7 27.0 13.8 11.2 14.8 39.9 123.1 61.7 67.0 21.0 44.4 99.2 99.1 41.5 81.3 78.3 156.5 77.6 82.3 74.9 51.9 100.4 49.7 119.0 171.9 87.8 202.1 102.4 60.6 103.4 69.0 30.3 119.6 73.3 36.5 33.1 90.3 39.2 48.3 63.3 74.9 89.1 63.4 60.2 138.3 140.3 9.7 48.7 66.5 41.1 116.3 63.1 87.8 31.3 154.2 104.6 66.7 95.6 88.9 47.8 50.5 43.1 38.3 62.3 63.9 100.3 47.5 130.2 80.2 101.8 184.6 105.1 104.9 68.1 99.8 5.1 26.3 26.2 6.7 21.4 10.7 36.4 29.2 7.3 9.3 28.4 29.3 1.6 12.7 4.3 3.5 32.3 14.2 14.0 14.8 15.0 17.4 13.3 15.3 12.1 12.6 13.2 13.0 13.8 14.8 6.0 3.2 13.5 55.2 29.1 19.5 33.5 30.6 48.9 59.3 13.7 9.9 18.1 17.2 18.8 18.4 47.9 41.4 19.0 68.9 25.4 27.7 1.2 10.9 23.3 14.2 31.2 45.4 77.3 18.7 74.2 24.8 26.0 11.3 9.5 38.1 12.8 98.7 17.2 77.4 62.9 23.9 26.4 8.1 11.4 4.0 47.2 9.5 10.6 30.9 9.0 19.8 37.0 55.3 60.1 31.8 20.1 35.0 63.4 31.6 89.8 51.1 15.5 49.9 26.3 21.7 23.1 2.8 7.4 43.6 21.6 30.9 61.9 67.2 21.7 27.0 SFXN2 SLC56A2 ENSG00000156398 "Sideroflexin 2" Q96NB2 10 102714538-102743492 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 17.9;parathyroid gland: 12.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 33.3;Hepatocytes: 21.2;Proximal tubular cells: 43.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "T-47d: 38.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA018150, HPA026834" Enhanced Approved Mitochondria NA NA "Cluster 32: T-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA018150: AB_1856790, HPA026834: AB_1856791" "unprognostic (1.70e-2)" "prognostic favorable (2.28e-4)" "unprognostic (3.30e-2)" "unprognostic (2.95e-1)" "unprognostic (6.10e-2)" "unprognostic (1.44e-2)" "prognostic favorable (9.95e-4)" "unprognostic (4.24e-2)" "unprognostic (9.69e-2)" "unprognostic (3.98e-2)" "unprognostic (1.32e-1)" "unprognostic (8.98e-3)" "prognostic favorable (2.28e-5)" "unprognostic (1.20e-1)" "unprognostic (2.14e-1)" "unprognostic (3.77e-2)" "prognostic favorable (6.52e-4)" 1.5 1.1 1.2 1.9 2.8 3.0 2.8 3.9 1.7 1.6 3.6 1.9 2.5 2.7 3.6 1.4 3.6 1.1 0.6 1.8 0.8 17.9 4.2 1.6 2.6 1.0 0.5 3.4 3.1 12.7 2.7 3.4 1.2 2.2 3.0 2.7 4.9 1.3 0.7 1.9 1.9 1.1 0.2 2.1 3.3 1.2 1.8 3.2 3.8 0.2 1.9 0.9 0.7 2.1 4.2 2.3 3.5 3.7 1.3 0.9 5.1 1.4 0.6 1.8 0.9 7.2 1.9 9.1 2.7 1.2 1.0 3.0 0.7 4.8 1.0 1.6 2.8 13.1 4.4 4.5 0.6 7.5 1.1 1.0 0.7 1.8 1.8 1.1 1.7 7.7 6.0 4.2 1.1 4.0 11.5 2.5 2.3 4.0 0.8 5.5 4.3 1.3 1.7 3.5 2.6 2.5 1.2 3.1 0.6 1.4 38.4 1.6 1.2 1.4 4.4 1.8 3.1 4.6 6.5 7.9 1.7 9.0 1.2 1.6 0.5 0.2 1.9 0.2 1.7 0.8 1.9 2.0 0.7 2.5 3.0 2.5 0.9 1.9 0.3 1.7 2.0 0.7 1.2 2.8 3.9 1.7 1.8 0.8 1.0 0.5 1.2 0.2 1.8 2.1 1.0 0.0 10.1 5.2 3.8 0.9 3.0 0.8 4.0 6.1 7.3 5.2 2.5 4.3 2.0 1.8 33.3 9.1 2.4 2.5 9.8 1.9 0.8 7.3 4.2 2.2 3.6 4.2 5.4 2.8 4.4 3.2 8.2 10.0 0.0 9.2 5.0 21.2 9.6 0.0 5.5 5.0 0.0 7.5 0.6 0.5 2.1 2.4 0.0 8.4 0.8 1.1 4.1 7.1 2.9 1.4 0.8 1.5 6.7 4.4 2.4 43.1 0.4 15.1 0.0 2.7 1.7 1.2 1.3 3.3 1.3 4.5 2.8 2.6 7.3 2.9 SFXN3 "SFX3, SLC56A3" ENSG00000107819 "Sideroflexin 3" Q9BWM7 10 101031234-101041244 "Metabolic proteins, Predicted membrane proteins" "Amino-acid transport, One-carbon metabolism, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 177.5;Proximal enterocytes: 119.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008028, HPA048105" Approved Enhanced Mitochondria NA NA "Cluster 46: Basophils - DNA binding" "Cluster 45: Intestine - Brush border" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "HPA008028: AB_1079938, HPA048105: AB_2680265" "unprognostic (2.55e-1)" "unprognostic (3.32e-2)" "unprognostic (4.94e-2)" "unprognostic (2.82e-2)" "unprognostic (4.94e-3)" "prognostic unfavorable (3.79e-4)" "unprognostic (3.84e-3)" "unprognostic (8.46e-2)" "unprognostic (1.05e-2)" "unprognostic (9.09e-3)" "unprognostic (1.04e-3)" "unprognostic (1.48e-1)" "prognostic unfavorable (4.94e-4)" "unprognostic (3.56e-1)" "unprognostic (3.05e-2)" "unprognostic (3.70e-2)" "unprognostic (1.71e-1)" 20.1 10.7 16.2 11.8 19.0 6.2 14.9 19.4 21.2 17.9 15.7 13.9 31.7 18.0 21.5 8.1 18.3 16.4 15.1 19.7 12.9 12.0 4.3 21.3 7.9 18.5 15.8 12.7 9.1 18.3 9.0 21.0 19.2 12.0 10.4 23.4 11.1 16.5 3.6 22.2 37.5 25.4 12.7 10.7 11.0 7.2 18.2 6.4 9.9 7.9 7.1 14.9 14.7 19.3 44.4 16.9 1.7 5.2 43.5 46.0 4.4 26.4 92.7 33.0 26.4 28.1 47.4 1.9 24.8 62.1 27.7 31.8 7.9 57.7 14.4 12.3 10.2 5.3 27.1 20.4 29.8 4.2 41.2 31.8 8.3 29.1 27.3 91.8 73.5 12.5 0.4 1.4 54.4 7.3 1.9 6.4 2.1 16.2 40.3 4.3 32.5 12.0 48.5 6.8 9.0 44.1 14.4 1.7 39.3 11.8 13.8 31.2 60.9 29.0 22.7 26.0 13.1 6.6 2.7 0.2 70.7 23.7 23.7 10.6 18.1 9.1 11.0 13.4 8.5 2.4 7.4 7.6 19.1 1.1 4.5 5.6 3.2 5.5 7.8 2.9 8.7 11.7 16.2 19.0 19.4 21.2 19.7 12.9 18.5 15.8 19.2 12.7 18.2 19.3 17.1 12.8 5.3 7.5 3.9 13.9 5.0 6.3 2.8 60.2 6.9 7.0 3.2 18.6 4.6 5.5 47.9 1.2 21.2 7.3 1.9 31.7 51.9 25.2 13.4 17.5 5.4 4.8 14.2 15.3 40.9 17.4 7.7 5.6 14.5 55.5 20.0 0.9 37.4 10.1 12.2 7.8 4.1 21.3 29.9 177.5 17.4 24.3 33.8 1.0 12.0 7.7 9.2 5.0 16.0 38.5 10.8 14.7 10.4 2.9 119.1 14.3 38.8 24.0 13.1 6.7 12.0 1.4 0.7 1.3 10.9 10.9 19.7 2.7 5.6 3.4 SGIP1 DKFZp761D221 ENSG00000118473 "SH3GL interacting endocytic adaptor 1" Q9BQI5 1 66533383-66751139 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "retina: 131.4" "Group enriched" "Detected in many" 4 "Astrocytes: 390.1;Cone photoreceptor cells: 350.3;Excitatory neurons: 323.3;Inhibitory neurons: 401.5;Oligodendrocyte precursor cells: 482.0;Oligodendrocytes: 363.6;Rod photoreceptor cells: 344.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 29.9;BJ hTERT+: 38.0;fHDF/TERT166: 24.5;hTERT-RPE1: 15.8;RPTEC TERT1: 27.5;SH-SY5Y: 15.3;U-138 MG: 27.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017963 Approved Approved Mitochondria NA NA "Cluster 77: Retina - Visual perception" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 9: Photoreceptor cells - Phototransduction" Mitochondria "HPA017963: AB_10964882" "unprognostic (1.74e-2)" "unprognostic (2.77e-1)" "unprognostic (2.86e-1)" "unprognostic (1.07e-1)" "unprognostic (1.74e-1)" "unprognostic (9.04e-2)" "unprognostic (9.51e-2)" "unprognostic (7.64e-2)" "unprognostic (1.86e-1)" "unprognostic (1.61e-1)" "unprognostic (1.83e-1)" "unprognostic (1.95e-1)" "unprognostic (3.48e-7)" "unprognostic (1.77e-2)" "unprognostic (1.29e-1)" "unprognostic (4.25e-2)" "unprognostic (9.63e-2)" 7.4 4.3 12.2 1.9 15.5 0.2 2.7 6.3 17.4 10.4 0.0 3.1 1.6 10.6 4.6 2.7 3.8 4.6 5.0 15.3 5.8 18.0 0.7 8.3 0.7 5.1 5.7 1.6 0.5 0.2 7.7 1.9 5.3 5.8 1.5 131.4 1.7 5.0 2.5 1.6 2.0 3.8 1.6 0.3 3.3 4.4 5.5 0.7 8.9 1.2 0.4 2.7 5.4 10.1 0.0 0.0 0.0 0.0 0.9 5.5 0.0 29.9 38.0 2.3 3.4 0.0 0.0 0.0 0.1 24.5 0.2 0.0 0.0 0.1 4.3 0.0 0.0 1.1 0.4 0.0 6.5 0.0 0.0 4.1 0.0 2.3 0.0 15.8 11.3 0.2 0.0 0.0 13.8 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.1 27.5 0.0 0.7 15.3 0.0 0.0 0.0 0.6 0.0 1.1 1.9 27.3 0.0 0.7 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.2 15.5 6.3 17.4 15.3 5.8 5.1 5.7 5.3 1.6 5.5 10.1 5.0 0.0 0.0 390.1 0.1 1.0 0.3 0.4 0.0 89.8 0.2 4.7 2.5 2.8 0.0 9.2 350.3 0.1 0.0 0.1 7.9 0.5 0.6 2.9 7.8 13.8 0.0 0.0 323.3 0.0 0.0 15.8 0.5 5.7 10.1 0.0 0.4 0.2 0.2 74.0 401.5 0.0 0.0 0.0 1.1 1.2 2.1 0.4 10.6 48.7 0.0 49.4 0.0 482.0 363.6 0.0 0.0 11.3 0.8 0.8 0.0 0.2 0.0 344.1 13.1 3.2 32.2 0.2 0.4 0.1 1.0 0.3 0.5 0.0 0.1 0.3 SH3GL3 "CNSA3, EEN-B2, HsT19371, SH3D2C, SH3P13" ENSG00000140600 "SH3 domain containing GRB2 like 3, endophilin A3" Q99963 15 83447228-83618743 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 77.2;choroid plexus: 19.4;testis: 26.5" "Group enriched" "Detected in many" 4 "Early spermatids: 557.6;Late spermatids: 1307.0;Oligodendrocytes: 1142.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 35.8;HEK 293: 16.8;K-562: 29.9;RH-30: 11.1;SuSa: 15.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039381, HPA077877" Enhanced Approved Mitochondria NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA039381: AB_10794635, HPA077877: AB_2686863" "unprognostic (1.10e-3)" "unprognostic (6.62e-2)" "unprognostic (4.25e-2)" "unprognostic (1.86e-1)" "unprognostic (6.01e-2)" "unprognostic (2.37e-1)" "unprognostic (9.76e-2)" "unprognostic (2.26e-1)" "unprognostic (8.20e-3)" "unprognostic (2.72e-3)" "unprognostic (1.43e-6)" "unprognostic (4.42e-2)" "unprognostic (3.59e-2)" "unprognostic (2.93e-1)" "unprognostic (5.78e-4)" 0.1 0.1 43.6 0.0 53.8 0.2 0.1 35.9 72.3 0.5 19.4 0.1 0.0 0.5 0.6 1.7 2.2 0.0 0.2 43.8 46.1 0.9 0.0 2.5 0.1 42.3 47.6 0.0 0.0 0.0 0.8 0.5 46.0 0.5 0.0 4.9 0.8 0.5 0.0 0.3 0.0 0.0 40.5 0.0 0.0 26.5 43.2 9.1 0.0 0.0 0.7 0.5 0.5 77.2 0.1 0.0 3.0 2.8 0.0 0.0 2.6 0.0 0.0 0.3 0.1 0.0 0.0 0.0 1.4 0.0 0.6 0.0 35.8 2.0 0.0 0.0 16.8 6.2 0.0 0.0 0.0 0.0 0.6 0.1 0.6 0.0 0.0 0.0 0.0 8.1 29.9 0.0 0.1 0.8 2.4 0.0 4.4 0.0 1.1 0.0 11.1 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 15.2 0.0 0.0 0.4 0.0 2.9 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.6 53.8 35.9 72.3 43.8 46.1 42.3 47.6 46.0 40.5 43.2 77.2 0.1 9.6 1.7 5.9 0.0 0.9 1.4 0.5 18.2 5.4 0.1 0.4 0.6 0.0 0.3 3.7 0.0 0.9 0.0 0.0 0.0 0.6 557.6 0.1 0.1 0.9 0.0 0.0 192.6 0.0 1.7 2.6 0.0 0.1 0.0 0.2 0.4 0.0 0.4 77.4 225.2 0.0 0.0 0.0 0.0 1307.0 9.3 0.5 1.8 6.5 0.0 3.1 0.0 29.1 1142.7 0.3 0.0 4.1 0.0 0.9 0.0 0.1 3.8 1.1 0.0 0.0 0.8 29.0 8.5 9.0 0.1 0.7 0.0 17.6 0.0 0.7 SIRT5 ENSG00000124523 "Sirtuin 5" Q9NXA8 6 13574227-13615158 "Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 52.5;Distal tubular cells: 52.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021798, HPA022002, HPA022992" Approved Supported Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 38: EFO-21 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA021798: AB_1856911, HPA022002: AB_1856913, HPA022992: AB_1856915" "unprognostic (8.53e-2)" "unprognostic (7.79e-2)" "unprognostic (4.71e-2)" "unprognostic (5.26e-3)" "unprognostic (6.19e-2)" "unprognostic (1.63e-1)" "unprognostic (8.72e-2)" "unprognostic (1.38e-1)" "unprognostic (8.54e-3)" "unprognostic (2.77e-3)" "unprognostic (1.02e-1)" "unprognostic (1.65e-1)" "prognostic favorable (8.76e-10)" "unprognostic (2.39e-1)" "unprognostic (6.88e-2)" "unprognostic (6.86e-2)" "unprognostic (2.36e-3)" 7.2 6.0 9.4 5.2 10.6 5.8 6.6 10.4 12.2 5.4 13.5 8.1 7.7 6.1 5.6 5.6 9.2 5.2 28.6 10.5 10.6 11.5 33.5 5.4 8.3 9.2 9.6 10.1 6.7 16.2 7.3 5.6 9.9 6.4 8.7 6.1 10.6 6.8 33.4 7.9 9.8 5.9 8.4 9.6 8.2 6.8 10.9 8.2 9.0 38.0 7.2 6.0 5.4 11.1 10.5 8.9 8.1 10.4 5.7 8.9 7.6 5.1 5.3 6.1 8.0 12.9 11.1 14.1 35.7 4.3 10.9 16.9 7.4 11.1 7.6 5.9 10.3 8.5 5.6 20.5 11.0 6.7 6.7 7.8 19.9 4.5 19.9 12.7 10.3 20.3 13.8 4.6 6.5 12.3 8.2 13.2 7.7 16.9 13.7 15.4 4.4 24.4 10.3 11.0 13.7 4.5 4.3 7.9 25.9 25.0 11.6 4.9 8.6 6.6 3.4 4.2 5.8 11.6 15.4 10.7 4.5 7.3 8.4 0.7 6.0 16.7 9.9 9.2 10.7 14.0 13.0 9.5 6.3 12.7 11.8 10.8 2.6 11.8 17.3 5.9 10.7 7.9 9.4 10.6 10.4 12.2 10.5 10.6 9.2 9.6 9.9 8.4 10.9 11.1 16.6 28.9 3.2 30.0 8.2 4.1 11.4 14.9 10.8 7.3 9.7 9.9 52.5 15.7 16.8 11.0 0.0 20.5 6.6 9.4 52.8 13.0 2.9 13.1 5.4 12.3 6.1 15.8 36.6 6.7 10.5 6.7 6.6 8.1 0.0 23.5 9.7 25.7 9.4 1.7 39.2 13.2 8.2 13.9 3.8 2.0 8.1 8.4 5.4 14.0 6.3 11.6 10.3 15.1 25.8 7.2 13.4 5.7 4.7 6.2 18.1 34.1 22.5 7.2 0.0 9.8 6.6 8.5 12.0 9.8 4.5 10.7 7.9 13.2 15.0 9.0 SLC11A2 "DCT1, DMT1, NRAMP2" ENSG00000110911 "Solute carrier family 11 member 2" P49281 12 50979401-51028566 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Iron transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Respiratory ciliated cells: 109.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032139, HPA032140" Uncertain Supported Mitochondria No No "Cluster 27: Non-specific - Gene expression" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Mitochondria "HPA032139: AB_10964213, HPA032140: AB_10962932" "unprognostic (4.40e-3)" "unprognostic (1.41e-2)" "unprognostic (1.50e-1)" "unprognostic (2.07e-3)" "unprognostic (2.35e-1)" "unprognostic (1.92e-1)" "unprognostic (2.09e-1)" "prognostic favorable (3.07e-6)" "unprognostic (1.06e-2)" "unprognostic (1.99e-2)" "unprognostic (1.15e-1)" "unprognostic (7.28e-2)" "unprognostic (2.29e-1)" "unprognostic (3.20e-2)" "unprognostic (2.61e-1)" "unprognostic (2.32e-2)" "unprognostic (2.24e-1)" 12.1 17.0 12.8 14.0 21.6 15.9 30.3 19.6 18.1 29.3 12.7 16.4 53.8 15.7 17.6 23.9 21.4 17.7 14.7 13.2 16.5 22.5 25.6 23.2 10.3 22.8 18.3 12.8 22.6 42.5 10.9 23.7 22.9 24.4 16.2 23.1 31.2 19.3 18.4 20.3 13.8 15.3 19.1 8.7 17.8 13.3 18.5 19.2 41.6 20.3 17.2 20.4 13.9 31.1 19.0 22.4 31.4 28.7 33.5 28.6 106.3 19.7 73.9 19.0 21.8 30.6 35.3 11.8 38.8 22.8 35.7 25.3 26.6 19.2 21.9 17.1 17.4 27.4 29.2 35.5 35.7 19.0 54.5 31.6 24.3 32.7 35.1 45.6 22.8 23.6 24.4 5.6 22.4 21.7 21.8 12.9 46.6 19.8 15.5 14.7 28.6 21.1 23.4 27.7 21.6 19.0 16.3 47.1 20.9 36.2 50.8 12.6 26.8 19.2 15.8 21.5 10.9 14.1 20.4 4.7 54.1 10.2 8.3 0.6 4.7 1.9 4.2 6.8 3.7 2.6 3.3 4.3 7.0 3.3 4.6 4.3 2.3 6.0 4.8 2.9 2.9 3.4 12.8 21.6 19.6 18.1 13.2 16.5 22.8 18.3 22.9 19.1 18.5 31.1 9.8 38.5 46.1 32.7 6.9 15.4 24.8 84.0 22.2 26.6 37.6 18.5 15.5 25.8 69.4 57.0 18.8 27.0 11.9 14.0 3.9 30.6 1.5 31.7 11.6 13.1 16.4 64.8 33.6 28.3 22.5 17.3 15.3 43.6 71.4 20.1 11.4 41.3 35.2 28.6 38.1 14.3 42.7 16.9 25.4 1.7 9.6 30.1 26.6 26.2 15.7 26.5 6.2 51.8 94.5 20.6 15.0 8.6 8.2 47.8 13.2 9.0 109.6 17.8 6.6 14.2 13.2 9.0 12.2 14.3 13.4 19.4 10.7 10.4 15.0 23.1 SLC16A12 MCT12 ENSG00000152779 "Solute carrier family 16 member 12" Q6ZSM3 10 89430299-89556641 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Symport, Transport" Cataract "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "choroid plexus: 92.2;epididymis: 51.8;kidney: 85.2;pancreas: 25.3" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 18.1;Leydig cells: 27.1;Peritubular cells: 26.7;Proximal tubular cells: 69.2" "Cancer enriched" "Detected in many" 10 "renal cancer: 18.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC TERT1: 23.0;HSkMC: 8.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037587 Approved Mitochondria NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA037587: AB_2732475" "unprognostic (5.38e-2)" "unprognostic (1.29e-1)" "unprognostic (2.79e-2)" "unprognostic (2.28e-2)" "unprognostic (3.51e-1)" "unprognostic (5.35e-2)" "unprognostic (2.45e-1)" "unprognostic (1.32e-1)" "unprognostic (1.78e-2)" "unprognostic (2.42e-1)" "unprognostic (9.60e-2)" "unprognostic (2.31e-1)" "prognostic favorable (4.50e-12)" "unprognostic (3.84e-2)" "unprognostic (7.91e-2)" "unprognostic (8.29e-2)" "unprognostic (1.84e-3)" 1.8 2.5 0.8 0.1 1.1 0.0 1.9 1.0 2.7 9.2 92.2 0.8 0.1 1.4 51.8 0.3 4.1 0.1 4.9 2.9 0.3 85.2 2.0 2.5 0.1 0.5 1.6 1.3 25.3 0.1 3.4 11.6 0.6 0.6 0.2 0.0 0.4 14.1 1.6 0.5 0.3 0.3 1.2 0.0 1.0 3.3 1.0 0.4 6.2 2.5 0.0 0.4 0.7 0.6 0.2 0.0 0.0 0.0 3.0 23.0 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.1 0.0 1.2 0.2 0.0 0.3 0.5 0.0 0.0 0.0 0.5 0.0 3.7 0.0 0.0 8.2 0.2 1.2 1.5 2.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.0 2.8 0.0 0.1 0.1 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 1.1 1.0 2.7 2.9 0.3 0.5 1.6 0.6 1.2 1.0 0.6 0.8 3.2 3.9 3.3 0.6 0.0 2.2 0.1 0.0 0.1 4.6 0.1 3.3 1.5 2.9 14.7 0.0 16.4 0.1 0.0 15.6 0.0 8.3 11.5 0.8 1.3 18.1 0.0 0.3 4.1 1.1 2.2 0.0 1.0 1.3 0.0 0.4 2.2 1.2 3.3 0.4 0.2 0.0 0.0 0.9 4.8 27.1 1.0 0.0 11.2 0.1 0.0 0.0 0.0 0.4 2.1 0.1 26.7 0.0 0.7 0.0 69.2 6.2 0.6 13.1 3.4 7.8 0.2 0.5 0.0 0.3 9.0 0.9 0.1 0.0 1.8 SLC22A4 "DFNB60, MGC34546, OCTN1" ENSG00000197208 "Solute carrier family 22 member 4" Q9H015 5 132294394-132344190 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Ion transport, Sodium transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.7" "Group enriched" "Detected in many" 5 "Erythroid cells: 57.0;Proximal enterocytes: 25.6;Respiratory ciliated cells: 78.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "neutrophil: 36.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 36.2" "Cell line enhanced" "Detected in many" "BJ hTERT+: 59.1;U-138 MG: 24.4" "Region enhanced" "Detected in all" "cerebellum: 64.5" "Low region specificity" "Detected in all" "CAB015468, HPA036974" Approved Approved Mitochondria NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" Mitochondria "CAB015468: , HPA036974: AB_2732474" "unprognostic (1.33e-1)" "unprognostic (2.20e-1)" "unprognostic (3.91e-2)" "unprognostic (8.42e-3)" "unprognostic (6.17e-2)" "unprognostic (6.22e-3)" "unprognostic (4.17e-3)" "unprognostic (3.33e-1)" "unprognostic (1.30e-1)" "unprognostic (9.79e-2)" "unprognostic (1.95e-3)" "unprognostic (7.82e-2)" "unprognostic (1.74e-2)" "unprognostic (2.31e-3)" "unprognostic (1.20e-1)" "unprognostic (1.95e-2)" "unprognostic (4.06e-2)" 1.9 3.0 2.1 2.9 1.9 20.7 2.2 3.7 1.8 1.5 1.1 2.0 3.5 1.4 1.4 0.4 11.3 1.9 1.9 1.9 3.6 7.1 0.8 2.9 0.3 4.0 3.7 2.1 0.6 2.6 2.6 1.0 3.4 4.0 2.2 2.2 1.7 1.4 7.2 1.3 9.1 1.0 3.6 5.1 1.4 0.6 3.4 0.4 0.7 2.7 0.2 1.4 0.9 2.9 1.9 3.0 0.2 0.7 1.3 1.0 0.9 12.9 59.1 9.7 10.1 1.1 3.3 0.6 3.6 7.6 7.2 3.2 0.0 2.1 6.8 2.6 0.3 0.1 5.6 0.2 1.0 4.1 0.0 2.3 0.4 5.3 4.9 3.5 4.3 0.3 5.3 6.7 7.6 1.1 0.0 9.5 0.3 0.3 3.2 0.0 0.8 0.4 1.5 0.2 0.8 0.4 14.0 0.9 0.4 0.4 0.6 2.4 5.2 24.4 2.4 9.7 3.3 0.0 2.7 0.0 7.2 4.7 2.9 0.0 5.6 5.8 0.0 1.3 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 36.2 0.0 0.4 0.3 0.0 1.2 2.1 1.9 3.7 1.8 1.9 3.6 4.0 3.7 3.4 3.6 3.4 2.9 1.1 3.2 0.0 5.5 0.1 0.8 1.0 3.8 1.8 2.0 1.9 1.3 0.8 1.5 10.0 0.0 0.0 1.0 0.1 8.8 0.0 3.2 0.0 4.7 1.8 3.8 1.2 57.0 7.2 0.4 2.3 3.1 0.5 2.2 0.0 0.6 1.4 0.0 4.0 3.3 8.0 0.8 4.1 0.8 0.8 0.3 0.6 3.7 0.0 1.9 2.2 1.6 0.0 4.5 2.3 1.9 1.7 0.0 0.1 1.7 25.6 8.6 78.5 0.4 0.0 9.3 1.8 0.3 0.4 0.2 0.4 2.5 0.2 0.1 1.0 0.9 SLC22A5 "CDSP, OCTN2, SCD" ENSG00000197375 "Solute carrier family 22 member 5" O76082 5 132369710-132395613 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 56.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 63.9;Proximal enterocytes: 56.2" "Cancer enhanced" "Detected in all" "renal cancer: 8.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HeLa: 34.7;SiHa: 37.8" "Low region specificity" "Detected in some" HPA063062 Approved Mitochondria NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA063062: AB_2684934" "unprognostic (3.88e-1)" "unprognostic (1.69e-1)" "unprognostic (2.19e-2)" "prognostic favorable (2.87e-5)" "unprognostic (5.37e-3)" "unprognostic (1.18e-1)" "unprognostic (1.50e-2)" "unprognostic (9.24e-2)" "unprognostic (1.57e-1)" "unprognostic (5.09e-2)" "prognostic favorable (7.36e-4)" "unprognostic (3.53e-2)" "prognostic favorable (8.36e-4)" "unprognostic (1.12e-2)" "unprognostic (2.98e-2)" "unprognostic (2.17e-2)" "unprognostic (1.17e-2)" 5.3 6.6 7.5 2.0 7.9 0.9 4.9 7.8 7.8 5.0 14.4 12.4 13.7 4.0 11.1 3.9 8.4 4.1 14.2 7.3 8.0 26.7 7.8 3.2 1.2 7.8 7.8 5.6 8.2 17.9 11.0 4.2 7.4 9.1 9.4 3.7 6.4 11.2 56.1 6.0 16.9 2.5 7.5 2.5 6.0 3.8 8.0 2.1 5.4 22.3 1.8 5.0 5.0 7.8 6.1 14.4 0.9 11.3 4.4 2.1 19.3 2.7 2.9 4.5 6.2 10.7 12.2 2.9 6.0 2.6 13.1 14.3 9.4 7.0 5.3 3.6 11.6 1.5 34.7 4.9 7.3 2.4 2.4 2.0 12.9 3.1 15.8 7.6 1.2 5.2 6.8 1.8 4.4 10.4 3.6 2.4 1.0 10.5 6.2 1.3 0.0 15.9 13.5 15.2 4.8 3.3 37.8 28.9 7.6 2.9 13.5 3.1 0.7 0.7 3.9 9.5 3.3 6.0 12.8 0.1 2.9 5.9 2.7 0.0 2.0 0.0 1.1 1.0 1.2 0.6 1.1 1.4 3.1 0.6 1.1 1.4 0.2 0.8 0.3 0.2 2.1 1.0 7.5 7.9 7.8 7.8 7.3 8.0 7.8 7.8 7.4 7.5 8.0 7.8 3.0 9.6 8.2 23.5 3.8 7.6 7.5 4.7 13.1 6.7 16.9 5.3 5.6 21.5 5.5 16.5 12.5 23.6 3.2 63.9 1.9 9.8 2.0 13.7 10.3 2.6 7.2 1.7 11.9 5.2 5.5 5.6 16.3 26.6 0.0 6.1 2.9 8.6 4.2 10.1 11.1 14.3 8.2 6.7 1.6 2.8 6.5 5.9 5.4 17.8 1.3 9.4 0.0 7.1 4.2 6.4 26.3 4.1 4.8 14.2 56.2 22.2 9.4 7.1 0.0 17.7 3.8 8.4 2.8 9.6 6.3 8.2 4.0 0.3 18.0 9.0 SLC25A13 "ARALAR2, CITRIN, CTLN2" ENSG00000004864 "Solute carrier family 25 member 13" Q9UJS0 7 96120220-96322147 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Transport "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 150.1" "Cell type enhanced" "Detected in all" "Hepatocytes: 153.4;Oligodendrocytes: 439.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018997 Enhanced Supported Mitochondria NA NA 21000 "Cluster 14: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA018997: AB_1857023" "unprognostic (3.61e-2)" "unprognostic (7.99e-2)" "unprognostic (6.99e-2)" "unprognostic (7.19e-2)" "unprognostic (1.14e-1)" "unprognostic (3.44e-2)" "unprognostic (1.42e-2)" "unprognostic (6.67e-2)" "unprognostic (2.31e-2)" "unprognostic (5.46e-2)" "unprognostic (1.01e-1)" "unprognostic (6.99e-2)" "prognostic favorable (9.14e-4)" "unprognostic (1.15e-1)" "unprognostic (1.05e-1)" "unprognostic (3.32e-1)" "unprognostic (7.09e-2)" 9.2 14.3 7.0 8.9 13.7 8.0 10.3 13.7 10.0 8.0 15.1 16.3 16.0 7.6 10.2 9.6 9.5 9.9 6.6 6.7 9.9 32.3 150.1 7.9 7.1 13.6 12.2 7.8 9.6 13.8 8.3 16.1 13.0 8.2 17.8 19.4 7.7 12.5 7.0 12.3 13.4 6.7 10.1 10.0 14.4 7.4 11.3 3.9 13.7 3.3 8.7 11.0 7.6 20.2 45.3 39.2 44.2 15.5 7.5 6.0 61.8 11.2 8.5 26.5 26.7 70.7 41.2 20.2 51.9 7.2 57.8 26.3 50.1 16.2 31.0 8.0 33.0 23.0 34.4 55.4 17.4 29.5 17.4 15.8 16.9 22.7 20.4 10.1 31.0 3.0 65.9 7.6 13.0 49.6 0.1 27.6 78.0 47.8 24.0 11.6 26.3 46.8 63.7 42.1 21.1 69.0 38.8 81.1 67.3 72.9 24.2 22.4 18.2 19.6 43.6 46.8 34.5 15.2 40.8 12.7 24.1 28.0 32.9 0.4 3.1 2.2 1.4 4.5 1.5 2.4 1.1 1.3 6.1 1.2 0.7 0.9 0.6 2.0 5.1 3.1 1.2 1.4 7.0 13.7 13.7 10.0 6.7 9.9 13.6 12.2 13.0 10.1 11.3 20.2 31.5 9.6 12.6 60.7 19.7 7.4 8.5 8.6 16.5 36.5 13.6 17.1 8.3 27.1 9.2 18.4 54.2 29.2 8.9 32.1 27.4 19.8 11.0 44.0 23.2 20.7 37.8 15.3 26.6 19.1 26.5 18.8 44.4 34.2 14.5 30.4 11.7 153.4 23.2 10.1 43.7 22.3 12.2 23.8 10.0 11.1 13.1 21.5 21.4 82.4 13.2 17.6 8.2 53.3 439.6 22.6 23.7 15.8 12.7 14.9 27.1 74.9 14.2 47.3 13.1 19.0 16.9 7.0 14.5 25.4 8.0 20.0 7.9 21.6 25.5 15.4 SLC25A14 "BMCP1, UCP5" ENSG00000102078 "Solute carrier family 25 member 14" O95258 X 130339888-130373361 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Respiratory ciliated cells: 34.2;Spermatogonia: 37.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060316 Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 16: U-266 - Nucleosome" "Cluster 49: Ciliated cells - Cilium organization" Mitochondria "HPA060316: AB_2684251" "unprognostic (1.65e-2)" "prognostic favorable (1.72e-5)" "unprognostic (1.82e-1)" "unprognostic (2.74e-1)" "unprognostic (1.27e-1)" "unprognostic (1.16e-1)" "unprognostic (3.36e-3)" "unprognostic (8.92e-3)" "unprognostic (3.52e-2)" "unprognostic (2.95e-3)" "prognostic favorable (1.78e-4)" "unprognostic (2.18e-2)" "prognostic unfavorable (5.52e-6)" "unprognostic (6.05e-2)" "unprognostic (1.12e-1)" "unprognostic (6.92e-2)" "prognostic favorable (1.39e-5)" 2.5 5.6 10.7 2.1 11.5 2.7 3.3 8.2 12.6 3.3 7.3 3.6 1.3 4.1 6.5 2.6 5.9 2.6 4.7 11.4 14.3 3.2 2.5 2.8 2.8 8.7 9.0 4.0 3.4 4.2 10.8 2.2 9.8 3.0 2.4 10.2 3.2 3.7 3.7 2.9 2.4 4.5 8.2 2.3 3.0 6.6 11.5 3.9 3.4 2.3 3.3 2.6 2.5 8.8 9.0 11.7 8.1 6.1 5.4 5.0 4.4 6.6 8.7 12.3 12.6 4.7 5.3 6.1 22.6 9.0 14.7 4.9 11.9 5.0 12.2 7.6 15.0 2.0 10.7 11.1 7.8 7.7 3.5 4.7 5.9 15.8 4.8 7.4 7.1 8.4 4.9 8.5 20.2 13.8 8.2 10.8 6.7 9.7 18.4 6.9 10.6 12.2 7.5 3.8 10.4 9.2 7.0 7.0 11.7 5.3 4.5 4.3 4.8 6.8 4.5 15.6 13.6 7.8 21.0 5.0 12.3 9.3 6.2 3.2 3.4 2.6 3.0 2.8 3.6 3.9 2.4 2.8 3.7 2.0 1.9 3.1 4.1 3.8 2.7 4.5 4.7 2.4 10.7 11.5 8.2 12.6 11.4 14.3 8.7 9.0 9.8 8.2 11.5 8.8 4.5 6.4 2.2 5.9 5.6 9.9 8.3 13.3 7.4 10.0 6.6 6.1 4.1 8.6 5.3 3.7 2.1 9.1 4.3 4.5 17.6 10.2 15.8 16.0 5.5 5.1 9.0 3.4 12.7 9.1 8.2 5.4 5.6 4.2 3.8 9.7 7.5 4.3 5.2 6.7 11.9 3.8 12.2 4.7 4.1 7.7 5.0 4.9 8.8 5.6 4.5 8.2 3.1 4.5 5.3 9.0 4.2 8.2 9.0 4.2 4.7 10.7 34.2 13.6 6.6 5.3 9.2 29.1 37.3 7.3 8.4 5.3 5.8 6.5 4.5 6.5 SLC25A16 "D10S105E, GDA, HGT.1, ML7" ENSG00000122912 "Solute carrier family 25 member 16" P16260 10 68477998-68527523 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036243, HPA044580" Uncertain Approved Mitochondria NA NA "Cluster 17: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA036243: AB_2675019, HPA044580: AB_10962723" "unprognostic (1.71e-1)" "unprognostic (1.54e-1)" "unprognostic (3.08e-2)" "unprognostic (1.27e-1)" "unprognostic (6.75e-2)" "unprognostic (2.68e-2)" "unprognostic (1.23e-2)" "unprognostic (9.13e-3)" "unprognostic (1.92e-1)" "unprognostic (4.13e-2)" "unprognostic (8.65e-2)" "unprognostic (1.17e-1)" "unprognostic (8.37e-3)" "unprognostic (2.10e-1)" "unprognostic (2.79e-1)" "unprognostic (2.06e-2)" "unprognostic (1.44e-3)" 10.3 3.6 5.1 2.1 5.3 3.7 4.1 7.1 7.9 2.1 0.0 3.2 3.8 3.5 3.2 2.6 2.1 2.3 2.8 5.0 5.6 5.8 11.4 3.1 2.7 2.7 3.5 2.3 5.1 3.5 2.6 2.8 3.4 8.2 2.8 4.7 4.5 2.8 4.9 3.0 3.8 2.6 2.2 2.4 4.5 1.5 7.0 2.0 3.5 2.3 2.0 2.7 2.1 6.1 2.8 1.1 3.2 4.4 4.2 5.0 3.4 3.8 4.2 2.4 2.6 6.6 1.9 3.0 2.7 7.6 1.3 1.6 10.2 1.9 6.1 2.2 6.3 1.6 3.5 2.9 5.1 5.2 3.4 4.3 4.9 4.6 6.4 3.6 2.0 2.6 1.8 4.8 5.2 2.6 2.9 3.7 0.7 0.8 14.8 1.6 2.3 1.0 6.8 9.2 2.2 1.8 5.4 5.2 4.4 2.2 2.9 2.1 8.9 3.6 4.8 6.1 4.5 4.9 2.8 4.9 3.5 4.2 1.6 1.4 0.7 0.7 0.4 0.5 0.4 0.4 0.4 0.3 0.5 0.8 0.4 0.6 1.3 0.6 0.4 0.8 0.4 0.3 5.1 5.3 7.1 7.9 5.0 5.6 2.7 3.5 3.4 2.2 7.0 6.1 9.6 44.8 20.7 23.5 9.9 6.4 6.3 4.9 4.6 19.2 11.0 6.7 10.4 12.8 7.4 12.9 39.6 19.0 12.4 12.9 11.7 8.1 9.9 9.6 9.3 7.8 15.0 9.9 44.0 19.2 32.3 8.8 20.9 14.1 8.2 6.1 13.9 37.7 10.6 20.2 53.7 9.4 8.2 10.3 6.5 13.0 3.1 7.9 1.8 13.1 8.2 9.5 15.5 29.7 48.0 14.4 7.8 7.9 16.4 13.5 17.7 21.4 9.9 31.2 0.0 13.4 11.3 4.5 2.5 10.5 6.8 59.8 9.4 9.4 9.0 10.6 SLC25A19 "DNC, MCPHA, MUP1, TPC" ENSG00000125454 "Solute carrier family 25 member 19" Q9HC21 17 75272981-75289510 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 82.2;Langerhans cells: 160.3;Spermatocytes: 79.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021936 Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "HPA021936: " "unprognostic (2.28e-1)" "unprognostic (7.05e-3)" "unprognostic (8.21e-2)" "prognostic unfavorable (8.72e-5)" "unprognostic (2.31e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (1.21e-7)" "unprognostic (6.71e-2)" "unprognostic (2.73e-1)" "unprognostic (2.85e-1)" "unprognostic (7.72e-2)" "unprognostic (1.77e-3)" "unprognostic (2.71e-3)" "unprognostic (3.58e-2)" "unprognostic (4.44e-2)" "unprognostic (1.17e-1)" "unprognostic (2.13e-1)" 10.9 31.2 11.6 16.0 12.4 8.0 6.4 13.1 13.3 7.3 12.4 9.8 9.4 6.7 2.4 8.6 6.3 6.2 10.6 11.7 12.6 10.9 8.8 11.7 22.9 14.9 12.6 6.2 8.8 8.1 4.8 12.1 13.2 6.1 8.8 3.1 6.2 3.7 14.5 4.9 8.5 7.1 13.0 14.6 10.9 33.0 14.7 8.6 6.0 16.7 18.8 11.5 5.7 14.7 28.3 34.8 6.2 18.4 13.6 7.0 20.0 18.1 7.0 20.3 20.5 59.8 17.4 89.8 12.8 6.4 17.7 24.7 43.5 20.9 25.3 26.5 70.5 41.1 40.4 58.4 11.5 58.7 44.9 6.1 11.6 31.5 25.2 4.7 33.9 44.9 51.0 41.9 6.5 59.3 61.8 59.3 13.5 55.3 67.8 47.4 19.8 85.1 14.1 19.7 60.7 15.3 19.3 51.4 22.2 10.2 32.1 47.3 12.0 12.1 24.1 23.5 49.0 102.7 53.4 95.8 9.5 66.9 15.5 0.3 21.0 2.3 16.2 25.2 16.6 36.3 12.7 15.4 24.9 29.7 14.2 14.7 1.7 10.0 14.8 31.0 17.7 14.5 11.6 12.4 13.1 13.3 11.7 12.6 14.9 12.6 13.2 13.0 14.7 14.7 5.1 6.4 6.7 3.3 27.6 15.2 10.8 6.0 2.8 1.2 5.4 7.5 0.6 2.8 6.1 7.3 2.1 7.5 13.3 8.6 23.5 6.5 18.0 5.6 8.7 6.7 3.0 11.1 3.1 5.3 82.2 8.6 9.7 3.5 11.4 2.7 2.5 2.9 44.1 3.3 3.5 6.2 4.1 9.5 160.3 24.1 3.1 31.5 24.9 4.7 38.8 1.6 11.3 2.0 2.4 5.1 8.6 3.4 26.5 14.1 6.5 6.4 3.9 6.0 6.6 5.9 10.0 79.6 11.9 7.9 12.9 8.9 12.5 11.4 11.0 9.7 SLC25A23 "APC2, FLJ30339, MGC2615" ENSG00000125648 "Solute carrier family 25 member 23" Q9BV35 19 6436079-6465203 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 238.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 164.2;Proximal enterocytes: 106.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009675, HPA050883" Approved Supported Mitochondria NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 65: Brain - Ion transport" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA009675: AB_2668252, HPA050883: AB_2681260" "unprognostic (3.51e-1)" "unprognostic (1.53e-3)" "unprognostic (1.52e-1)" "prognostic unfavorable (1.29e-4)" "unprognostic (2.05e-2)" "unprognostic (3.65e-3)" "unprognostic (3.43e-2)" "unprognostic (1.31e-3)" "unprognostic (1.27e-1)" "unprognostic (3.82e-1)" "unprognostic (1.30e-1)" "unprognostic (3.25e-1)" "prognostic favorable (1.10e-12)" "unprognostic (8.95e-2)" "unprognostic (3.20e-1)" "unprognostic (5.44e-2)" "unprognostic (4.22e-1)" 28.8 38.0 144.8 12.0 238.7 0.8 18.0 77.5 200.1 32.1 72.0 94.4 39.3 41.8 24.0 64.7 36.6 21.4 79.0 206.5 95.1 45.0 38.5 24.0 9.2 108.8 98.2 33.6 24.2 58.8 22.2 4.7 109.5 35.0 49.1 41.2 68.9 40.0 90.8 33.5 40.5 65.5 82.7 11.9 41.3 9.5 101.4 7.2 60.7 78.2 31.2 55.8 31.1 115.8 58.2 22.9 32.2 101.9 42.3 18.6 14.9 17.0 26.4 31.0 37.2 58.2 37.1 32.2 40.0 41.3 34.1 48.0 66.3 39.0 24.3 0.1 58.6 23.2 46.7 46.2 39.2 1.6 52.5 53.3 33.4 27.6 12.0 62.9 32.8 34.7 68.8 39.4 6.2 41.6 20.7 32.8 23.6 61.0 71.1 10.0 8.8 49.4 83.3 10.2 2.4 31.9 11.7 70.8 30.0 34.8 37.1 50.1 11.7 9.8 41.8 2.6 11.2 7.3 10.7 28.3 4.5 54.2 15.6 0.5 0.0 0.0 2.0 0.0 0.4 1.0 1.1 0.9 0.2 0.4 1.5 1.4 0.0 0.3 0.0 0.4 1.3 0.4 144.8 238.7 77.5 200.1 206.5 95.1 108.8 98.2 109.5 82.7 101.4 115.8 6.2 9.6 20.9 11.8 7.0 10.5 8.8 11.5 12.0 13.1 18.9 15.6 39.5 47.1 10.0 46.0 8.4 1.4 4.5 164.2 19.6 54.7 15.9 8.2 6.4 8.0 13.8 1.3 24.7 28.5 1.8 10.2 12.8 17.5 7.0 17.9 16.1 38.0 2.7 8.4 17.9 34.5 10.2 3.0 2.6 71.2 19.0 1.4 17.8 12.2 1.0 28.7 4.1 17.1 12.6 55.5 57.9 29.3 17.6 13.6 106.8 28.7 6.4 22.0 13.1 12.1 12.7 0.5 4.6 34.1 23.3 0.8 5.2 39.5 34.2 30.3 SLC25A24 "APC1, DKFZp586G0123" ENSG00000085491 "Solute carrier family 25 member 24" Q6NUK1 1 108134043-108200849 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Distal enterocytes: 126.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028519, HPA063636" Enhanced Enhanced Mitochondria NA NA 19000 "Cluster 7: Monocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA028519: AB_10603890, HPA063636: AB_2685068" "unprognostic (1.94e-2)" "unprognostic (7.30e-3)" "prognostic favorable (1.01e-4)" "unprognostic (7.11e-2)" "unprognostic (1.64e-2)" "unprognostic (2.91e-1)" "unprognostic (8.54e-4)" "unprognostic (1.51e-2)" "unprognostic (7.39e-2)" "unprognostic (1.29e-1)" "unprognostic (1.15e-3)" "unprognostic (6.18e-2)" "unprognostic (6.76e-2)" "unprognostic (2.21e-1)" "unprognostic (1.67e-1)" "unprognostic (1.03e-1)" "unprognostic (2.29e-1)" 10.0 6.2 0.8 5.3 0.7 3.8 8.2 0.6 1.3 12.5 0.8 13.5 11.4 6.6 3.2 6.0 6.7 6.8 4.9 0.7 0.8 6.3 1.6 9.1 5.1 0.8 0.7 5.9 4.2 8.2 2.8 9.4 0.9 4.0 16.0 6.7 6.7 4.6 3.7 4.3 12.3 8.7 0.6 5.7 6.9 3.2 1.0 5.0 7.1 4.5 4.9 10.1 7.0 0.7 38.2 8.9 28.8 8.6 17.9 23.4 11.4 13.0 17.0 25.1 27.4 11.3 12.9 0.0 10.3 28.7 10.9 14.1 7.9 24.0 35.1 7.9 4.4 2.4 13.4 5.2 14.9 6.1 4.9 17.6 17.0 15.0 18.5 16.8 19.6 5.7 6.2 13.0 32.2 28.7 3.7 1.4 14.3 17.3 8.1 5.7 33.9 12.6 16.9 22.8 5.0 8.7 17.4 14.9 17.5 27.5 13.3 10.7 10.5 13.8 6.2 23.2 15.0 3.0 2.3 0.0 5.0 11.8 8.2 0.4 0.5 0.4 0.3 0.5 0.3 0.1 0.2 0.2 0.4 0.4 0.1 0.3 0.1 0.2 0.7 0.3 0.4 0.1 0.8 0.7 0.6 1.3 0.7 0.8 0.8 0.7 0.9 0.6 1.0 0.7 33.9 54.5 27.8 5.5 24.2 15.6 20.4 20.6 17.1 14.7 25.5 16.8 15.5 17.2 33.5 18.4 8.4 7.1 16.3 126.7 21.5 31.2 3.2 62.0 46.7 28.6 18.1 6.7 18.0 36.9 60.2 23.2 40.2 61.7 22.2 20.9 29.6 1.2 54.1 10.1 14.9 43.2 18.3 51.8 32.8 2.9 19.6 50.0 23.2 16.9 44.7 12.7 11.3 14.6 20.8 67.6 51.2 18.0 9.7 14.3 54.4 24.9 55.2 33.9 52.6 27.2 26.5 6.2 2.4 24.8 14.9 6.2 23.9 41.8 59.1 33.8 SLC25A26 ENSG00000144741 "Solute carrier family 25 member 26" Q70HW3 3 66133610-66388116 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026887 Supported Supported Mitochondria NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA026887: AB_2189921" "unprognostic (1.93e-1)" "unprognostic (1.29e-1)" "unprognostic (1.38e-2)" "unprognostic (1.12e-1)" "unprognostic (2.32e-1)" "unprognostic (7.83e-2)" "unprognostic (7.94e-2)" "unprognostic (5.38e-2)" "unprognostic (1.53e-1)" "unprognostic (3.54e-1)" "unprognostic (9.21e-2)" "unprognostic (8.43e-2)" "prognostic favorable (1.73e-5)" "unprognostic (4.73e-2)" "unprognostic (2.59e-1)" "unprognostic (1.33e-1)" "unprognostic (2.07e-1)" 15.8 16.0 9.6 5.6 9.9 12.9 15.0 8.7 11.0 12.7 6.8 18.1 7.8 13.3 9.4 15.9 12.7 7.8 28.3 10.1 8.7 18.5 25.9 11.6 10.7 9.1 9.3 16.5 15.5 14.9 10.2 7.7 9.2 13.5 9.5 8.5 16.1 9.0 42.4 22.0 13.3 7.8 9.3 13.5 17.4 14.3 11.1 8.6 15.8 21.0 9.6 17.5 14.1 11.3 10.7 10.4 6.5 12.4 13.9 13.1 13.9 9.0 15.7 10.7 10.2 13.5 13.9 12.3 5.5 15.1 14.3 7.6 7.3 15.8 11.7 11.5 16.8 16.3 8.1 19.2 14.7 22.5 13.4 17.7 29.6 8.4 21.3 11.2 8.9 21.5 9.2 12.8 12.9 12.5 9.9 28.3 20.8 23.2 6.8 10.0 11.7 19.4 10.1 8.3 5.4 14.6 12.4 11.8 21.4 10.9 9.8 19.7 10.4 12.7 11.0 15.9 16.6 21.1 30.6 15.1 17.4 21.1 14.7 1.8 9.9 6.1 15.4 10.8 14.5 19.3 16.9 16.4 18.3 16.2 20.5 17.5 0.9 18.1 6.7 17.5 17.7 13.4 9.6 9.9 8.7 11.0 10.1 8.7 9.1 9.3 9.2 9.3 11.1 11.3 11.6 32.1 22.2 22.9 29.5 35.8 38.6 45.7 28.5 17.7 36.1 34.0 106.9 30.0 25.0 18.4 12.5 36.8 27.3 14.1 35.2 28.8 33.3 17.2 13.6 20.5 18.6 9.2 55.5 45.1 44.6 26.1 17.3 19.1 19.6 21.1 13.2 39.1 30.3 11.8 51.4 29.2 28.5 22.3 26.5 28.6 16.1 15.8 37.4 31.9 21.4 26.5 32.0 32.2 63.9 27.6 20.8 21.8 18.7 49.1 30.8 57.7 16.2 24.5 19.7 31.7 22.1 29.4 32.9 28.2 36.8 32.7 39.6 22.3 33.3 37.8 SLC25A27 "FLJ33552, UCP4" ENSG00000153291 "Solute carrier family 25 member 27" O95847 6 46652915-46678190 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 53.2;Excitatory neurons: 78.1;Inhibitory neurons: 78.1;Oligodendrocyte precursor cells: 127.2;Oligodendrocytes: 88.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 53.6;hTCEpi: 24.2;U-698: 27.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069732 Supported Mitochondria NA NA "Cluster 21: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 68: Oligodendrocytes - Mixed function" Mitochondria "HPA069732: AB_2686185" "unprognostic (2.16e-2)" "unprognostic (2.19e-1)" "unprognostic (9.86e-3)" "unprognostic (4.93e-2)" "unprognostic (1.87e-1)" "unprognostic (2.03e-1)" "unprognostic (2.81e-1)" "unprognostic (1.24e-1)" "unprognostic (1.22e-1)" "unprognostic (1.35e-1)" "prognostic favorable (6.16e-4)" "unprognostic (3.82e-3)" "unprognostic (1.01e-1)" "unprognostic (7.53e-2)" "unprognostic (1.18e-1)" "unprognostic (1.74e-1)" "unprognostic (7.47e-3)" 33.7 23.7 34.7 5.9 46.5 1.5 31.6 76.5 45.5 57.9 42.1 50.4 6.7 41.4 69.9 18.6 52.9 19.8 36.0 41.3 34.0 52.2 43.8 25.2 5.7 35.9 36.7 94.3 34.1 21.1 114.7 3.0 36.5 72.2 15.5 118.8 28.4 24.4 21.2 41.1 24.4 22.2 28.5 15.8 31.7 32.5 44.9 1.2 70.8 10.9 4.8 43.0 40.9 57.1 3.5 2.3 3.9 13.1 14.6 10.0 0.1 2.0 6.2 1.8 0.4 0.0 4.9 1.4 8.9 3.3 4.3 6.9 1.8 5.8 1.2 0.0 19.7 0.0 53.6 5.0 7.7 0.1 0.6 15.7 24.2 0.1 15.2 9.4 0.4 13.5 0.2 0.1 1.6 1.4 0.0 0.2 2.0 3.5 5.2 0.0 5.0 0.2 9.7 12.5 11.8 1.3 9.2 0.6 5.4 5.7 9.8 0.0 1.4 8.1 5.3 0.8 1.7 5.3 0.0 27.4 1.3 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.7 46.5 76.5 45.5 41.3 34.0 35.9 36.7 36.5 28.5 44.9 57.1 3.6 3.2 4.6 53.2 0.2 0.9 4.4 0.5 9.1 32.0 3.6 7.5 9.5 2.8 1.7 5.5 29.2 0.0 0.0 0.7 0.0 1.2 29.0 5.7 6.1 4.5 6.0 2.5 78.1 0.7 0.1 7.2 1.1 5.1 1.3 7.3 1.8 2.2 0.2 20.2 78.1 1.3 2.0 0.3 0.3 22.7 3.1 0.8 1.8 27.2 0.0 7.0 0.0 127.2 88.5 0.2 0.7 5.3 0.2 4.5 0.5 1.0 5.0 36.2 0.0 8.8 7.5 0.5 1.8 4.4 2.4 0.0 0.2 8.8 1.5 2.8 SLC25A3 PHC ENSG00000075415 "Solute carrier family 25 member 3" Q00325 12 98593591-98606379 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1537.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1748.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045709 Supported Mitochondria NA NA 83000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA045709: AB_10965843" "unprognostic (1.16e-2)" "unprognostic (4.68e-1)" "unprognostic (1.95e-2)" "unprognostic (1.52e-1)" "unprognostic (1.56e-2)" "unprognostic (6.38e-2)" "unprognostic (3.25e-3)" "unprognostic (9.41e-2)" "unprognostic (4.98e-2)" "unprognostic (6.43e-2)" "unprognostic (5.65e-2)" "unprognostic (7.40e-2)" "prognostic favorable (8.11e-7)" "unprognostic (3.45e-1)" "unprognostic (2.99e-1)" "unprognostic (8.66e-3)" "unprognostic (4.72e-2)" 300.9 550.7 131.2 184.7 136.0 209.2 267.5 159.3 146.5 224.3 209.3 418.9 396.4 283.5 226.1 437.7 248.9 136.2 1237.8 132.6 160.4 419.8 370.1 255.7 201.7 148.9 149.6 290.2 392.2 499.7 216.9 192.4 153.0 209.9 347.6 167.2 302.7 220.9 1537.4 275.7 321.2 257.4 150.4 235.1 423.5 90.8 159.0 205.7 225.1 1233.2 312.8 294.7 264.6 135.4 731.4 447.1 620.0 509.6 534.1 891.5 1005.3 622.8 724.1 704.3 573.4 787.6 316.4 1003.2 376.9 633.0 320.3 573.7 616.9 741.3 680.6 402.9 651.8 589.5 297.4 563.3 683.0 665.7 416.6 857.3 616.8 494.2 681.2 994.3 990.8 488.8 654.9 240.5 782.7 436.5 642.5 724.2 605.4 540.6 988.5 703.0 730.3 1075.0 858.8 559.6 355.5 506.1 740.1 565.5 1009.8 504.4 771.0 676.3 782.0 371.2 390.0 442.8 603.4 486.5 648.5 678.1 295.6 368.3 494.9 184.7 408.9 223.2 244.7 520.2 285.6 298.5 270.8 271.4 534.7 222.6 281.3 269.8 166.6 288.5 545.2 321.7 377.4 637.0 131.2 136.0 159.3 146.5 132.6 160.4 148.9 149.6 153.0 150.4 159.0 135.4 319.2 214.7 294.8 46.0 392.2 376.0 590.6 751.4 495.1 223.1 442.5 549.3 1748.6 370.3 384.5 215.2 79.2 785.9 480.8 727.5 874.6 512.1 41.7 217.9 275.3 328.6 312.4 413.5 44.9 879.5 946.2 393.1 390.4 288.7 210.4 477.9 278.1 416.3 589.4 292.7 49.7 470.7 370.2 467.9 280.7 29.0 255.1 449.1 437.6 34.7 593.5 317.3 294.5 32.2 42.2 632.9 602.7 256.5 442.7 652.4 945.5 1029.4 201.1 230.2 302.4 470.5 733.5 126.1 169.9 796.6 362.4 814.7 356.3 536.0 729.1 769.9 SLC25A31 "ANT4, DKFZP434N1235" ENSG00000151475 "Solute carrier family 25 member 31" Q9H0C2 4 127730400-127774292 "Predicted membrane proteins, Transporters" "Antiport, Differentiation, Spermatogenesis, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 272 "testis: 47.3" "Cell type enriched" "Detected in some" 8 "Spermatocytes: 198.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015064, HPA016841, HPA046835, HPA071684" Uncertain Enhanced Mitochondria NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "HPA015064: AB_1847691, HPA016841: AB_1847690, HPA046835: AB_2679831, HPA071684: AB_2686431" "unprognostic (8.15e-2)" "unprognostic (1.62e-1)" "unprognostic (2.70e-1)" "unprognostic (5.32e-1)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 13.5 3.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 198.2 23.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SLC25A34 DKFZp781A10161 ENSG00000162461 "Solute carrier family 25 member 34" Q6PIV7 1 15736258-15741392 "Predicted membrane proteins, Transporters" Transport "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "heart muscle: 14.4;intestine: 14.0;skeletal muscle: 37.8;tongue: 47.3" "Cell type enriched" "Detected in many" 5 "Proximal enterocytes: 44.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "SK-MEL-30: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069806 Approved Mitochondria NA NA "Cluster 32: T-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 45: Enterocytes - Digestion" Mitochondria "HPA069806: AB_2686202" "unprognostic (2.06e-1)" "unprognostic (4.72e-1)" "unprognostic (1.15e-1)" "unprognostic (2.43e-1)" "unprognostic (2.58e-1)" "unprognostic (8.08e-3)" "unprognostic (1.98e-2)" "unprognostic (9.92e-2)" "unprognostic (1.55e-1)" "unprognostic (1.55e-1)" "unprognostic (1.80e-4)" "unprognostic (5.74e-2)" "unprognostic (6.10e-2)" "unprognostic (4.02e-1)" "unprognostic (1.82e-1)" "unprognostic (4.04e-2)" "unprognostic (2.40e-4)" 2.4 4.4 3.7 1.0 3.8 3.4 1.8 6.8 4.8 3.6 2.4 5.7 14.0 3.1 0.8 1.7 2.9 1.5 14.4 3.6 3.4 4.7 5.6 2.4 1.2 3.2 3.1 4.2 4.9 0.6 3.8 1.3 3.5 2.4 2.0 1.9 4.7 0.8 37.8 1.8 13.7 1.1 2.7 3.7 2.2 2.5 3.7 0.5 3.4 47.3 0.5 2.8 2.3 3.6 0.3 0.2 1.5 0.6 0.7 0.3 0.6 0.2 0.1 0.3 0.2 0.6 0.8 0.4 0.3 0.3 0.8 0.3 0.2 0.2 0.3 0.5 0.3 0.7 0.5 0.2 0.2 0.2 0.9 0.3 1.1 0.4 0.1 0.9 0.2 2.0 0.3 1.3 0.2 0.7 1.7 0.9 1.3 0.2 0.4 0.9 1.3 0.4 0.1 0.0 0.3 1.2 0.3 0.4 3.4 1.4 0.7 1.0 0.8 0.7 1.0 1.0 0.2 1.7 1.6 0.3 0.2 0.9 0.6 0.5 0.1 0.1 0.4 0.0 0.9 0.1 0.9 0.6 0.0 0.2 1.2 0.7 0.6 0.6 0.0 0.1 0.4 0.3 3.7 3.8 6.8 4.8 3.6 3.4 3.2 3.1 3.5 2.7 3.7 3.6 0.9 0.0 0.0 6.2 0.4 0.3 0.3 0.6 0.0 2.6 0.5 0.5 2.7 1.5 0.2 0.0 0.0 0.3 0.3 8.8 0.0 0.2 0.3 0.4 1.3 1.2 3.5 0.0 5.1 0.2 0.4 0.8 2.0 1.7 0.0 1.3 2.2 2.3 1.5 3.3 4.6 3.1 0.0 1.9 0.3 1.0 0.9 1.5 0.0 2.8 1.1 1.8 0.0 2.5 1.7 0.3 8.0 0.4 0.0 0.6 44.6 3.7 0.0 1.8 0.0 2.7 0.9 0.6 0.6 1.1 0.1 1.4 0.6 0.4 5.5 0.7 SLC25A4 "ANT1, PEO2, PEO3, T1" ENSG00000151729 "Solute carrier family 25 member 4" P12235 4 185143266-185150382 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Host-virus interaction, Transport" "Cardiomyopathy, Disease variant, FDA approved drug targets, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "heart muscle: 245.1;skeletal muscle: 190.8;tongue: 346.6" "Cell type enriched" "Detected in all" 4 "Cardiomyocytes: 4722.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046835, HPA071684" Approved Supported Mitochondria NA NA 380000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 38: Heart - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA046835: AB_2679831, HPA071684: AB_2686431" "unprognostic (4.19e-2)" "unprognostic (1.06e-2)" "unprognostic (3.11e-1)" "unprognostic (8.85e-2)" "unprognostic (1.37e-1)" "unprognostic (2.90e-3)" "unprognostic (8.25e-2)" "unprognostic (1.26e-2)" "unprognostic (7.87e-2)" "unprognostic (1.60e-1)" "prognostic favorable (3.41e-4)" "unprognostic (2.05e-1)" "prognostic favorable (0.00e+0)" "unprognostic (1.98e-1)" "unprognostic (1.05e-1)" "unprognostic (1.73e-1)" "unprognostic (8.28e-3)" 4.7 5.7 14.0 1.6 15.3 0.4 4.6 22.6 30.6 3.4 6.8 21.0 3.0 5.9 3.5 10.1 5.8 3.9 245.1 16.7 11.8 10.4 7.3 4.5 1.5 11.6 10.7 4.9 5.2 7.8 9.5 1.7 11.8 8.9 3.9 19.9 9.0 12.6 190.8 3.3 6.8 8.1 9.4 3.1 15.7 4.7 12.5 1.4 5.2 346.6 1.2 9.8 3.6 18.2 0.7 3.1 2.5 5.1 2.7 0.3 4.6 2.6 0.8 3.1 3.0 6.8 1.7 2.3 1.8 3.1 2.4 2.5 9.8 2.7 2.0 3.9 8.4 1.6 4.7 8.1 5.5 1.4 1.5 2.0 6.6 4.7 1.3 7.2 2.3 4.0 3.8 1.7 1.9 5.0 1.6 3.1 4.1 2.2 6.6 2.5 1.3 3.2 6.9 4.8 8.1 6.2 3.1 1.3 12.5 4.5 2.4 1.1 1.7 0.2 1.4 1.5 3.4 7.3 3.5 2.9 2.2 0.3 2.8 0.0 0.0 0.0 1.7 0.0 1.3 1.5 0.5 1.4 0.0 1.0 0.4 1.2 0.1 0.3 0.0 1.3 0.5 0.6 14.0 15.3 22.6 30.6 16.7 11.8 11.6 10.7 11.8 9.4 12.5 18.2 37.5 86.6 76.4 22.9 37.9 44.1 159.0 119.9 30.1 180.6 42.9 53.5 4722.0 115.8 80.0 71.7 104.3 69.2 41.1 44.4 988.0 75.3 20.6 77.8 7.4 80.1 53.8 3.0 35.1 74.1 56.5 120.1 54.0 33.6 12.0 18.6 27.5 92.1 65.9 159.9 43.7 40.6 215.7 8.5 13.8 16.7 46.6 6.8 190.3 19.7 9.0 541.2 16.5 26.7 29.2 51.4 28.5 112.8 76.4 59.1 113.8 178.3 144.0 221.0 105.2 134.5 402.7 28.0 34.0 33.2 18.2 40.5 27.7 23.7 54.2 50.7 SLC25A42 MGC26694 ENSG00000181035 "Solute carrier family 25 member 42" Q86VD7 19 19063994-19113030 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 82.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 67.7;Hepatocytes: 52.1;Proximal tubular cells: 39.6;Rod photoreceptor cells: 41.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 2.7;MAIT T-cell: 1.4;memory B-cell: 3.3;memory CD4 T-cell: 1.5;memory CD8 T-cell: 2.4;naive B-cell: 3.2;naive CD4 T-cell: 1.0;naive CD8 T-cell: 1.4;NK-cell: 1.8;T-reg: 1.7" "Group enriched" "Detected in many" 6 "B-cells: 3.3;NK-cells: 1.8;T-cells: 2.7" "Cell line enhanced" "Detected in many" "K-562: 20.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049449 Approved Supported Mitochondria Yes No "Cluster 43: B-cells - Humoral immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 56: Bipolar cells - Visual perception" Mitochondria "HPA049449: AB_2680772" "unprognostic (2.27e-1)" "prognostic favorable (5.04e-4)" "unprognostic (5.79e-2)" "unprognostic (5.67e-2)" "unprognostic (1.35e-1)" "unprognostic (3.42e-3)" "unprognostic (1.27e-3)" "prognostic favorable (4.11e-4)" "unprognostic (6.89e-2)" "unprognostic (2.73e-1)" "unprognostic (1.37e-3)" "unprognostic (3.04e-2)" "unprognostic (5.29e-3)" "unprognostic (1.76e-1)" "unprognostic (2.39e-2)" "unprognostic (4.17e-2)" "unprognostic (2.03e-2)" 8.5 7.5 17.2 4.3 16.9 8.3 7.9 14.5 18.3 13.1 16.7 8.4 5.1 10.1 3.7 5.2 12.5 3.5 15.8 17.9 16.9 34.1 82.0 6.6 9.0 14.9 15.2 16.9 11.3 6.0 14.4 2.6 14.7 9.9 2.4 8.4 9.2 5.2 46.5 6.7 9.3 4.9 13.9 12.7 8.3 7.0 18.0 8.1 25.6 32.6 7.5 9.6 9.1 13.9 7.3 1.0 1.8 3.2 6.8 5.6 2.8 3.5 5.2 5.3 6.0 1.4 14.3 5.2 8.0 3.3 5.3 1.3 3.7 2.9 3.0 1.3 7.0 1.8 2.0 11.8 5.4 0.8 3.6 5.6 2.0 4.0 2.4 4.3 2.4 16.8 20.9 9.2 2.8 6.6 9.0 8.4 1.0 2.0 7.4 6.8 3.2 10.2 2.1 1.3 2.0 1.5 3.7 0.1 1.6 2.4 6.5 4.1 2.2 3.9 2.2 8.2 3.4 10.7 6.2 4.1 4.1 11.2 2.0 0.0 0.1 0.1 2.7 0.3 1.4 3.3 1.5 2.4 0.2 3.2 1.0 1.4 0.0 1.8 0.3 0.4 1.7 0.9 17.2 16.9 14.5 18.3 17.9 16.9 14.9 15.2 14.7 13.9 18.0 13.9 4.6 0.0 13.1 12.4 14.2 3.2 2.8 3.3 2.8 67.7 5.9 6.6 9.7 5.7 4.1 9.2 18.8 7.7 16.5 3.1 13.7 1.5 1.2 2.5 5.4 4.1 8.4 13.7 18.6 3.1 3.8 5.1 4.1 3.6 3.8 8.3 5.3 52.1 1.8 3.3 25.0 3.8 6.1 0.6 1.9 1.6 5.0 1.4 3.6 6.5 1.3 12.5 32.0 16.1 8.6 2.5 4.6 6.4 16.4 2.4 9.2 39.6 3.0 41.4 6.6 9.6 5.8 10.6 7.6 0.9 2.8 4.7 10.9 8.0 3.1 1.7 SLC25A46 ENSG00000164209 "Solute carrier family 25 member 46" Q96AG3 5 110738136-110765161 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 238.9;Late spermatids: 448.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039601, HPA071582" Approved Supported Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "HPA039601: AB_2676592, HPA071582: AB_2686422" "unprognostic (1.86e-1)" "unprognostic (3.29e-1)" "prognostic favorable (8.41e-4)" "unprognostic (4.91e-2)" "unprognostic (2.27e-2)" "unprognostic (2.25e-1)" "unprognostic (2.34e-1)" "unprognostic (1.77e-2)" "unprognostic (5.14e-2)" "unprognostic (1.97e-2)" "unprognostic (1.67e-1)" "unprognostic (2.40e-1)" "unprognostic (2.25e-2)" "unprognostic (2.26e-1)" "unprognostic (2.62e-1)" "prognostic unfavorable (2.52e-4)" "unprognostic (1.98e-1)" 22.9 15.9 10.4 19.9 11.8 17.6 16.4 12.7 16.7 18.5 7.8 22.1 23.8 14.7 10.5 21.2 10.7 15.8 31.1 12.2 12.2 29.7 30.0 16.7 22.5 12.4 10.2 11.7 15.4 20.6 4.9 17.0 13.2 15.7 21.6 18.8 13.3 16.0 55.8 14.9 20.9 20.8 10.3 15.7 20.1 21.9 11.2 24.8 19.8 60.2 26.8 19.0 6.6 14.1 36.2 27.7 25.7 20.7 65.2 60.2 9.9 44.3 55.9 47.5 59.3 37.6 28.7 96.8 44.8 50.1 61.9 29.6 41.0 71.2 54.3 61.8 20.8 40.1 35.2 25.6 53.1 37.3 40.2 49.9 25.4 55.5 39.6 29.5 31.9 37.2 31.4 56.4 54.1 27.3 54.0 17.2 18.1 25.7 24.7 26.0 57.0 71.5 35.1 39.2 46.7 33.5 37.7 29.7 49.7 23.7 30.9 35.3 42.5 43.6 21.0 40.7 54.4 111.8 76.2 68.4 48.0 43.8 24.0 29.2 16.0 13.2 12.3 19.0 12.5 14.4 13.7 12.9 17.0 14.5 14.5 14.8 6.6 20.9 17.7 11.1 18.2 17.4 10.4 11.8 12.7 16.7 12.2 12.2 12.4 10.2 13.2 10.3 11.2 14.1 21.3 22.4 24.8 40.8 26.7 22.9 9.1 16.0 31.9 16.8 15.7 10.8 63.5 11.5 12.9 20.2 22.9 21.7 18.0 34.8 19.6 18.1 238.9 10.4 20.1 18.9 23.4 29.9 73.3 25.6 18.2 22.6 34.7 12.1 19.0 16.2 26.7 43.9 27.2 18.5 63.9 28.3 32.6 26.1 21.0 448.2 21.1 23.9 30.2 31.9 28.1 21.9 17.5 49.8 91.8 18.9 22.8 22.2 73.8 8.0 26.5 41.7 14.9 14.1 19.7 18.5 22.6 23.3 14.2 30.0 26.9 20.5 23.9 22.7 24.0 6.8 SLC25A5 "2F1, ANT2, T2, T3" ENSG00000005022 "Solute carrier family 25 member 5" P05141 X 119468422-119471396 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Antiport, Chromosome partition, Host-virus interaction, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 2533.6;Proximal enterocytes: 2785.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046835, HPA071684" Approved Supported Mitochondria NA NA 640000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 45: Enterocytes - Digestion" Mitochondria "HPA046835: AB_2679831, HPA071684: AB_2686431" "unprognostic (1.25e-2)" "prognostic favorable (7.35e-4)" "prognostic favorable (7.47e-4)" "unprognostic (1.48e-1)" "unprognostic (4.58e-2)" "unprognostic (1.45e-2)" "unprognostic (2.73e-2)" "unprognostic (1.36e-1)" "unprognostic (6.52e-2)" "unprognostic (2.47e-1)" "unprognostic (1.60e-1)" "unprognostic (2.17e-1)" "prognostic favorable (8.06e-6)" "unprognostic (1.41e-1)" "unprognostic (2.65e-1)" "unprognostic (4.36e-2)" "unprognostic (3.03e-1)" 178.1 178.3 116.9 176.0 116.1 260.9 161.3 141.6 126.0 155.0 114.3 458.7 740.2 134.5 63.9 411.0 118.6 100.4 196.1 109.0 141.5 491.8 336.1 216.5 255.4 120.6 118.0 108.2 629.1 295.3 89.0 138.1 126.4 111.9 503.0 127.7 250.2 103.8 61.6 294.9 562.8 150.5 119.3 182.6 492.1 54.2 126.4 351.9 128.8 65.1 297.7 200.8 235.3 121.5 845.1 789.6 303.3 525.4 189.5 277.3 561.0 306.8 331.3 631.7 560.8 662.4 518.4 1059.3 400.9 296.1 456.1 576.9 752.1 640.5 572.5 281.1 711.2 357.5 418.7 477.0 239.8 984.0 566.1 303.7 705.2 652.2 412.6 240.1 660.4 535.0 292.5 425.9 350.1 1868.4 878.6 995.1 640.4 1147.6 1244.3 474.5 383.4 825.7 486.9 663.6 365.0 344.5 526.7 793.3 646.7 306.7 327.7 491.0 279.5 297.3 428.9 670.8 1122.2 494.6 656.3 847.4 329.5 987.7 492.2 113.4 603.4 170.2 170.7 1045.7 198.1 459.2 248.3 224.6 872.6 376.0 243.3 232.1 99.2 318.1 824.2 476.1 443.1 931.8 116.9 116.1 141.6 126.0 109.0 141.5 120.6 118.0 126.4 119.3 126.4 121.5 260.4 163.5 308.6 28.7 339.6 815.7 567.0 1615.3 398.9 109.8 406.2 413.5 131.2 301.7 609.2 187.6 60.5 1038.8 336.2 1379.0 2533.6 578.2 4.0 137.3 134.2 257.5 401.0 349.1 16.8 1056.4 463.1 214.4 543.3 157.6 192.9 306.0 146.7 333.6 881.7 26.9 25.5 856.4 1129.1 610.6 650.9 18.1 145.4 473.2 547.8 15.0 441.2 140.8 218.3 24.1 19.2 554.1 1061.8 110.6 419.9 522.3 2785.2 1622.3 239.5 199.0 131.5 163.9 506.7 11.5 119.2 1046.8 960.2 1589.1 291.2 626.6 1053.7 809.7 SLC25A51 "CG7943, MCART1, MGC14836" ENSG00000122696 "Solute carrier family 25 member 51" Q9H1U9 9 37879400-37904353 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 93.6;Late spermatids: 169.6;Spermatocytes: 44.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 16.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 16.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046388, HPA058261" Uncertain Approved Mitochondria NA NA "Cluster 34: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "HPA046388: AB_2679649, HPA058261: AB_2683657" "unprognostic (5.46e-2)" "unprognostic (2.28e-1)" "unprognostic (2.67e-2)" "unprognostic (5.63e-2)" "unprognostic (1.00e-2)" "unprognostic (1.35e-2)" "prognostic unfavorable (5.67e-5)" "unprognostic (6.87e-2)" "unprognostic (1.04e-1)" "unprognostic (7.98e-3)" "unprognostic (1.26e-3)" "unprognostic (5.37e-2)" "prognostic favorable (1.52e-4)" "unprognostic (8.27e-3)" "unprognostic (2.31e-1)" "prognostic unfavorable (2.21e-4)" "unprognostic (2.08e-2)" 9.0 3.1 3.1 5.0 3.5 12.0 4.1 3.4 4.4 5.4 2.3 4.5 7.5 4.1 4.7 5.6 3.4 5.0 4.5 3.7 4.1 6.3 3.1 5.2 5.7 3.4 3.3 3.8 5.9 8.3 4.1 4.7 4.0 3.5 4.1 4.8 4.7 3.7 6.1 5.7 6.0 5.8 2.6 5.7 4.3 8.0 3.1 5.6 4.6 7.4 6.5 4.3 3.5 4.4 12.4 10.1 7.3 11.6 34.4 15.2 7.4 10.6 10.7 8.8 12.6 13.0 5.2 26.2 5.9 24.2 12.5 6.1 19.6 14.5 16.5 18.0 6.1 8.0 27.5 18.0 19.1 12.5 11.1 15.3 16.7 13.4 16.6 13.6 16.1 24.4 17.9 20.2 19.1 7.3 15.2 3.2 9.2 12.7 7.1 10.6 9.9 16.1 8.7 8.9 15.2 10.0 8.3 10.1 6.0 12.2 5.4 13.7 17.3 14.7 17.4 7.2 12.8 7.7 17.5 17.5 19.4 9.3 12.3 16.7 1.5 2.8 1.6 3.1 2.7 2.6 1.7 2.3 1.1 1.5 1.6 1.8 1.3 1.9 1.3 0.5 2.7 0.9 3.1 3.5 3.4 4.4 3.7 4.1 3.4 3.3 4.0 2.6 3.1 4.4 4.3 9.6 1.1 13.4 9.3 4.7 5.8 7.6 8.6 4.0 5.1 3.8 6.3 5.7 4.6 1.8 4.2 3.7 7.6 3.8 17.6 9.5 93.6 2.5 5.3 4.3 3.6 6.9 22.0 7.2 14.1 5.2 8.2 5.1 3.8 3.4 3.9 3.6 11.7 1.7 21.3 5.8 0.0 5.7 4.7 169.6 3.7 8.8 1.8 19.7 8.4 5.3 3.1 16.1 22.1 7.3 7.2 4.1 14.3 3.8 17.4 16.8 2.2 3.7 0.0 4.3 4.5 44.0 10.2 11.7 5.8 4.0 6.5 4.8 3.6 3.8 SLC25A52 MCART2 ENSG00000141437 "Solute carrier family 25 member 52" Q3SY17 18 31759584-31760880 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 14 "testis: 8.9" "Group enriched" "Detected in some" 4 "Early spermatids: 55.3;Late spermatids: 106.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046388, HPA058261" Uncertain Approved Mitochondria NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "HPA046388: AB_2679649, HPA058261: AB_2683657" "unprognostic (8.97e-2)" "unprognostic (4.85e-2)" "unprognostic (2.93e-1)" "unprognostic (4.87e-1)" "unprognostic (2.50e-1)" "unprognostic (9.05e-2)" "unprognostic (2.97e-2)" "unprognostic (1.30e-4)" "unprognostic (7.15e-3)" "unprognostic (1.23e-1)" "unprognostic (1.44e-1)" "unprognostic (1.41e-1)" "unprognostic (3.34e-2)" "unprognostic (1.55e-1)" "unprognostic (1.41e-2)" 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.6 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.1 0.0 8.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.5 0.1 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.3 0.2 0.2 0.0 0.0 0.1 0.3 0.3 0.1 0.1 0.1 0.1 0.2 0.3 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 106.9 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.6 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SLC25A6 "ANT3, ANT3Y, MGC17525" ENSG00000169100 "Solute carrier family 25 member 6" P12236 X 1386152-1392113 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Antiport, Apoptosis, Host-virus interaction, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046835, HPA071684" Approved Supported Mitochondria NA NA 450000 "Cluster 39: Non-specific - mRNA processing" "Cluster 25: Pancreas - Digestion" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 32: Non-specific - Translation" Mitochondria "HPA046835: AB_2679831, HPA071684: AB_2686431" "unprognostic (1.13e-1)" "unprognostic (1.65e-2)" "unprognostic (4.79e-2)" "unprognostic (1.45e-1)" "unprognostic (2.14e-1)" "unprognostic (1.41e-1)" "unprognostic (1.01e-3)" "unprognostic (1.34e-1)" "unprognostic (8.07e-2)" "unprognostic (1.48e-1)" "unprognostic (1.37e-3)" "unprognostic (2.51e-1)" "unprognostic (3.96e-2)" "unprognostic (2.73e-1)" "unprognostic (1.69e-1)" "unprognostic (2.85e-1)" "unprognostic (4.57e-3)" 356.6 410.1 227.8 223.3 241.4 441.5 307.3 210.8 296.7 253.7 351.6 350.9 466.0 277.9 80.6 344.8 243.4 127.2 201.5 227.9 216.1 386.8 130.0 239.4 275.0 222.6 222.8 460.8 626.9 323.5 275.8 147.1 228.0 264.1 141.5 108.3 697.7 178.8 115.5 331.3 387.7 129.4 208.3 263.7 413.9 62.2 227.4 232.7 321.5 89.2 159.3 292.0 244.6 219.2 290.4 596.8 393.8 422.6 267.5 527.4 466.2 396.8 386.1 296.8 289.2 796.7 330.6 1023.0 334.1 264.9 445.6 179.2 269.5 482.0 89.8 260.3 886.0 545.0 396.0 899.7 642.2 398.1 649.8 870.1 882.2 235.8 335.9 367.5 441.6 315.7 407.2 233.8 284.5 575.4 791.1 733.3 516.0 105.5 802.2 378.8 333.8 828.3 351.4 693.6 682.9 1096.5 271.1 817.7 1239.7 224.1 466.1 832.5 505.5 305.1 169.6 596.5 422.1 606.7 110.5 705.9 48.7 389.9 170.3 34.2 739.8 47.2 319.5 808.7 466.9 671.4 431.3 377.9 985.9 532.5 396.1 399.7 34.4 359.9 832.3 461.2 447.6 1120.7 227.8 241.4 210.8 296.7 227.9 216.1 222.6 222.8 228.0 208.3 227.4 219.2 194.2 147.4 244.3 13.7 724.4 1151.2 1447.6 1800.6 421.8 286.1 981.3 710.8 106.0 371.8 704.7 316.3 98.0 1581.2 448.5 690.4 1659.2 752.6 11.4 164.4 388.1 473.0 928.4 471.3 15.1 1473.5 1229.8 507.8 374.1 245.3 343.6 698.0 529.4 149.7 1264.7 242.3 20.4 1208.1 819.9 1553.5 1299.4 45.8 667.9 764.0 754.2 17.8 1450.5 184.6 531.4 8.0 13.7 789.8 1127.8 366.3 604.9 1452.4 1564.9 1320.8 180.3 280.0 341.8 631.7 665.6 13.3 80.7 796.7 1321.5 1744.1 494.7 847.8 1524.3 1723.2 SLC37A4 "G6PT1, G6PT2, G6PT3, GSD1b, GSD1c, GSD1d" ENSG00000137700 "Solute carrier family 37 member 4" 11 119024114-119030906 "Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 139.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 171.6;Hepatocytes: 175.9;Proximal enterocytes: 277.2;Proximal tubular cells: 183.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 29.3;HEK 293: 28.0;Hep G2: 37.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038939, HPA038940" Enhanced Approved Mitochondria NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA038939: AB_2676279, HPA038940: AB_2676280" "unprognostic (4.77e-2)" "unprognostic (3.49e-1)" "unprognostic (2.08e-2)" "unprognostic (2.35e-2)" "unprognostic (4.70e-2)" "unprognostic (6.95e-3)" "unprognostic (1.09e-1)" "unprognostic (1.39e-1)" "unprognostic (4.08e-2)" "unprognostic (8.27e-3)" "unprognostic (4.72e-2)" "unprognostic (3.89e-1)" "unprognostic (1.98e-1)" "unprognostic (4.04e-2)" "unprognostic (2.60e-1)" "unprognostic (4.34e-2)" "unprognostic (5.39e-2)" 4.5 8.0 4.6 2.5 4.7 2.4 5.0 4.5 6.9 5.1 4.6 10.8 36.1 3.5 20.8 4.7 5.5 1.7 5.4 4.8 4.7 49.4 139.9 4.6 1.5 4.9 4.7 5.3 40.1 3.4 6.3 2.5 4.7 9.4 6.6 4.6 7.0 5.5 30.0 4.9 27.3 1.3 4.8 7.1 12.0 7.1 4.7 1.1 5.3 3.8 0.9 4.6 4.7 4.9 1.2 12.2 5.6 6.2 7.5 3.2 4.9 0.7 9.7 2.6 6.9 29.3 2.8 3.8 7.2 3.9 5.4 0.7 2.3 14.9 4.4 4.1 28.0 10.3 3.4 37.1 2.8 6.0 2.0 0.5 4.2 1.5 7.1 10.7 8.7 0.6 4.7 11.2 4.5 25.9 0.3 13.3 0.1 3.6 13.6 8.4 0.0 21.1 5.5 12.9 7.3 6.4 0.0 2.6 5.4 5.8 5.4 4.2 0.0 0.0 4.9 1.3 5.4 1.7 2.9 1.3 1.2 15.6 2.0 0.0 0.9 1.3 1.4 1.6 1.2 0.7 1.0 1.7 0.3 0.5 1.0 1.1 0.0 0.9 0.7 0.1 1.0 0.6 4.6 4.7 4.5 6.9 4.8 4.7 4.9 4.7 4.7 4.8 4.7 4.9 7.9 3.2 7.8 7.5 5.8 1.8 8.3 10.1 5.7 7.5 13.0 10.7 4.5 171.6 8.2 16.5 0.0 30.1 3.2 23.8 31.3 29.5 14.0 11.5 6.6 9.2 24.7 28.6 4.5 25.3 21.4 5.5 13.7 11.2 0.0 72.3 19.2 175.9 28.8 16.8 4.2 26.3 14.2 11.1 2.4 3.3 9.6 7.9 3.6 7.5 10.0 93.4 2.1 3.5 2.9 19.7 27.5 10.5 5.7 12.5 277.2 183.0 12.6 11.3 0.0 4.4 5.6 11.2 25.8 5.9 2.7 15.2 5.4 6.7 50.3 8.4 SLC41A1 MgtE ENSG00000133065 "Solute carrier family 41 member 1" Q8IVJ1 1 205789094-205813748 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 99.3;tongue: 75.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 175.0;Theca cells: 100.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014721, HPA015138" Uncertain Approved Mitochondria NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 38: Heart - Muscle contraction" "Cluster 44: HDLM-2 - Immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA014721: , HPA015138: AB_1857160" "unprognostic (1.18e-1)" "prognostic unfavorable (1.48e-4)" "unprognostic (2.77e-2)" "unprognostic (1.30e-2)" "unprognostic (2.30e-1)" "unprognostic (1.38e-2)" "unprognostic (2.37e-3)" "unprognostic (5.23e-2)" "unprognostic (5.53e-3)" "unprognostic (1.11e-1)" "unprognostic (1.87e-2)" "unprognostic (4.46e-2)" "unprognostic (3.09e-3)" "unprognostic (2.60e-1)" "unprognostic (1.67e-1)" "unprognostic (1.95e-1)" "unprognostic (1.65e-1)" 9.7 10.8 10.1 6.4 10.4 5.8 4.7 11.0 8.2 4.8 36.7 5.8 2.1 6.5 5.1 5.6 11.0 7.1 99.3 8.6 6.4 9.2 1.4 8.4 7.4 11.1 10.2 11.3 61.6 9.3 4.6 3.7 9.5 7.5 1.8 6.1 3.7 6.7 48.8 3.8 3.8 6.0 8.9 5.3 9.8 18.5 13.7 5.7 17.8 75.9 5.1 6.2 3.9 9.5 18.2 16.1 9.6 15.6 11.7 11.6 13.2 17.9 17.8 18.2 15.9 8.0 10.1 25.9 11.3 16.5 14.9 18.5 9.5 13.4 6.2 48.6 14.8 6.4 16.5 1.2 11.2 0.0 17.4 14.9 10.8 20.8 14.7 14.9 11.3 20.5 11.9 10.5 14.7 11.2 11.8 1.8 11.5 4.8 7.1 13.8 29.0 6.4 4.1 22.0 8.1 10.4 14.0 12.3 11.0 8.0 8.8 6.7 14.3 21.5 13.8 19.9 19.2 34.7 24.9 8.5 16.6 8.3 13.6 0.0 0.1 0.0 1.6 0.1 2.0 0.6 1.5 1.5 0.0 0.7 1.4 1.5 0.0 0.4 0.0 0.0 1.5 1.0 10.1 10.4 11.0 8.2 8.6 6.4 11.1 10.2 9.5 8.9 13.7 9.5 18.2 3.2 23.0 20.5 11.2 20.8 24.3 4.6 10.8 14.6 14.4 10.2 175.0 5.7 8.5 0.0 50.1 1.8 11.5 1.6 1.9 9.6 2.4 6.8 9.8 24.1 6.0 6.5 5.3 11.0 14.5 15.7 11.7 6.2 7.0 13.9 8.6 2.2 3.4 18.5 6.6 2.7 4.1 2.4 6.5 2.7 9.9 3.5 8.8 15.9 0.8 17.0 8.2 7.1 8.3 9.3 1.3 9.4 8.3 24.9 0.0 15.7 7.9 20.3 0.0 29.7 16.1 8.1 12.9 7.5 18.2 3.1 14.5 100.2 1.5 22.0 SLC6A17 ENSG00000197106 "Solute carrier family 6 member 17" Q9H1V8 1 110150494-110202202 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 52.9;pituitary gland: 25.3" "Group enriched" "Detected in some" 5 "Excitatory neurons: 60.6;Inhibitory neurons: 59.4" "Cancer enriched" "Detected in some" 9 "melanoma: 17.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SK-MEL-30: 36.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008043, HPA008044" Enhanced Approved Mitochondria NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA008043: , HPA008044: AB_1857192" "unprognostic (1.13e-1)" "unprognostic (1.37e-3)" "unprognostic (5.52e-3)" "unprognostic (3.00e-2)" "unprognostic (1.17e-1)" "unprognostic (4.88e-2)" "unprognostic (6.11e-3)" "unprognostic (3.87e-3)" "unprognostic (1.70e-2)" "unprognostic (1.80e-1)" "unprognostic (1.68e-2)" "unprognostic (2.94e-1)" "unprognostic (1.89e-2)" "unprognostic (1.73e-2)" "unprognostic (9.76e-2)" "unprognostic (1.38e-3)" "unprognostic (1.68e-3)" 0.4 5.9 21.6 0.2 26.3 0.1 0.3 1.2 52.9 0.1 0.0 0.3 0.0 0.1 1.0 0.4 0.1 0.1 0.1 20.1 9.6 1.3 0.0 0.1 0.0 13.7 8.2 0.0 1.4 8.8 25.3 0.8 10.5 0.1 0.1 6.0 0.6 0.1 0.1 6.2 0.1 0.1 0.0 0.0 0.7 1.8 24.8 0.0 0.3 0.1 0.0 0.1 0.1 15.7 0.0 1.5 0.0 0.0 0.0 0.0 0.0 5.5 0.5 2.1 0.2 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.0 1.9 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 1.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.9 0.8 6.2 1.9 36.0 1.0 0.9 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 7.1 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.6 26.3 1.2 52.9 20.1 9.6 13.7 8.2 10.5 0.0 24.8 15.7 0.0 0.0 0.0 2.6 0.0 0.5 0.0 0.1 0.0 5.1 0.2 0.4 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.9 0.0 1.2 0.0 0.0 0.5 0.0 0.0 60.6 0.0 0.5 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 59.4 0.0 4.1 0.0 0.0 0.7 0.0 0.0 10.6 3.7 0.0 0.7 0.0 4.5 2.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.8 0.0 0.7 0.4 0.0 1.8 0.0 0.4 0.1 0.0 0.0 0.0 0.0 SLIRP "C14orf156, DC50" ENSG00000119705 "SRA stem-loop interacting RNA binding protein" Q9GZT3 14 77708071-77761104 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1099.6;Proximal tubular cells: 1027.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020291 Approved Supported Mitochondria No Yes 32000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA020291: AB_1845563" "unprognostic (9.28e-2)" "unprognostic (4.88e-2)" "unprognostic (1.87e-1)" "unprognostic (3.62e-1)" "unprognostic (1.34e-1)" "prognostic unfavorable (4.88e-4)" "unprognostic (1.18e-1)" "unprognostic (8.23e-2)" "unprognostic (2.19e-1)" "unprognostic (1.14e-2)" "unprognostic (1.92e-2)" "unprognostic (1.35e-1)" "unprognostic (9.95e-3)" "unprognostic (1.52e-1)" "unprognostic (2.39e-1)" "unprognostic (3.60e-2)" "unprognostic (1.37e-1)" 121.9 131.0 241.0 80.4 251.7 122.7 155.0 250.5 391.0 92.8 228.9 161.3 112.5 91.5 196.3 163.7 89.6 68.3 336.8 249.8 251.6 203.0 211.2 81.1 82.8 251.4 247.5 82.0 110.5 145.2 120.2 91.9 248.6 95.7 141.3 109.9 105.0 90.3 364.5 92.1 107.6 97.0 248.2 92.9 140.2 122.9 245.9 97.4 94.6 442.3 113.5 123.8 101.8 261.2 422.5 867.3 340.9 330.8 226.0 227.7 441.2 240.0 234.8 484.1 419.6 1187.1 387.1 314.2 238.9 284.7 295.6 415.7 645.4 508.0 647.3 166.5 717.2 316.3 816.1 1199.5 343.4 211.8 216.6 242.5 332.3 387.3 428.2 232.4 408.7 403.2 321.2 172.8 430.0 1442.6 325.3 562.2 525.1 938.0 1211.5 294.8 282.9 345.6 508.8 840.3 425.5 274.1 253.3 533.0 360.3 373.7 555.7 360.9 227.0 237.1 422.5 254.0 416.9 184.8 374.7 605.0 325.7 407.2 309.6 88.9 276.1 103.9 105.2 275.3 112.0 169.4 139.0 104.6 239.8 143.1 143.4 120.3 87.8 93.3 288.8 247.4 154.9 216.2 241.0 251.7 250.5 391.0 249.8 251.6 251.4 247.5 248.6 248.2 245.9 261.2 130.4 109.0 140.0 8.5 112.3 178.8 164.5 542.9 92.8 68.8 168.8 154.3 1099.6 270.2 303.9 264.8 47.9 393.0 82.7 330.9 770.9 405.1 548.5 163.7 141.9 169.0 246.8 203.2 10.8 530.1 382.3 166.0 119.3 123.7 171.5 73.1 179.2 793.4 313.6 43.7 9.6 373.1 388.6 202.8 119.5 123.0 168.0 135.2 250.8 2.8 211.4 206.4 93.7 8.5 16.7 440.6 334.4 170.0 136.9 190.5 563.3 1027.1 254.5 126.8 170.9 178.6 202.7 382.6 210.3 178.5 214.4 240.5 80.6 84.7 404.0 163.8 SLITRK3 KIAA0848 ENSG00000121871 "SLIT and NTRK like family member 3" O94933 3 165186720-165197109 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.0;fallopian tube: 9.6;liver: 7.9" "Group enriched" "Detected in some" 6 "Bipolar cells: 8.4;Excitatory neurons: 11.0;Inhibitory neurons: 15.9;Oligodendrocyte precursor cells: 21.1" "Cancer enriched" "Detected in single" 22 "glioma: 7.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 2.6;HAP1: 2.2;SCLC-21H: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017636, HPA048042" Enhanced Approved Mitochondria No NA 2600000 "Cluster 15: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" Mitochondria "HPA017636: AB_1857232, HPA048042: AB_2732542" "unprognostic (8.91e-2)" "unprognostic (1.44e-1)" "unprognostic (4.08e-2)" "unprognostic (1.96e-1)" "unprognostic (5.16e-2)" "unprognostic (1.76e-1)" "unprognostic (9.59e-2)" "unprognostic (2.95e-2)" "unprognostic (1.03e-1)" "unprognostic (2.22e-1)" "unprognostic (6.74e-3)" "unprognostic (5.03e-1)" "unprognostic (2.38e-1)" "unprognostic (8.03e-4)" 0.1 0.1 3.4 1.0 3.1 0.0 0.1 4.1 8.4 5.4 0.0 2.6 0.4 7.3 0.9 4.4 9.6 0.2 0.4 9.0 2.8 0.1 7.9 0.3 0.0 0.2 0.1 0.9 0.0 0.0 0.1 0.0 0.5 1.7 1.6 3.1 0.2 5.4 0.3 0.0 1.1 3.7 0.9 0.0 0.4 0.4 0.7 0.0 0.1 0.0 0.0 0.5 0.9 1.3 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 3.1 4.1 8.4 9.0 2.8 0.2 0.1 0.5 0.9 0.7 1.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 11.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.7 2.2 0.0 0.0 15.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 21.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SMIM12 "C1orf212, FLJ90372" ENSG00000163866 "Small integral membrane protein 12" Q96EX1 1 34712737-34859755 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065331 Approved Approved Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA065331: AB_2685470" "unprognostic (2.21e-1)" "unprognostic (2.26e-1)" "unprognostic (3.68e-2)" "unprognostic (1.24e-1)" "unprognostic (1.97e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.18e-4)" "unprognostic (2.64e-1)" "unprognostic (2.05e-1)" "unprognostic (5.71e-2)" "unprognostic (3.57e-2)" "unprognostic (1.93e-1)" "prognostic favorable (1.15e-5)" "unprognostic (7.33e-2)" "unprognostic (6.70e-2)" "unprognostic (3.58e-2)" "unprognostic (2.52e-2)" 40.2 56.6 31.7 26.5 32.1 24.8 33.5 29.5 35.3 20.9 29.2 34.0 30.1 26.0 17.7 41.3 23.5 17.3 53.8 31.5 35.7 42.3 87.9 31.6 25.0 32.6 32.7 17.1 26.4 31.8 26.9 24.8 33.1 19.9 28.0 12.8 24.1 20.5 56.2 29.7 30.8 31.5 29.6 31.9 30.4 28.0 31.9 30.3 24.9 51.1 27.3 29.2 25.7 33.3 52.9 39.8 43.3 31.6 55.2 43.3 30.1 55.8 48.1 70.2 60.3 40.0 65.0 55.1 49.2 57.6 55.5 51.7 55.5 74.7 53.5 67.3 41.6 98.1 65.6 49.1 51.3 107.9 55.4 66.2 71.9 76.5 61.3 25.3 72.9 47.0 71.0 72.3 63.0 38.6 52.6 55.4 70.1 40.8 52.7 44.1 42.7 71.7 62.2 54.6 41.5 32.9 52.0 48.1 81.5 53.9 32.8 29.9 69.9 47.8 49.3 74.3 66.7 40.4 60.2 56.9 45.2 63.7 32.1 104.2 76.0 126.4 65.8 82.0 77.9 57.7 60.4 72.0 86.0 59.2 50.1 64.3 50.2 62.6 67.5 62.4 76.2 87.5 31.7 32.1 29.5 35.3 31.5 35.7 32.6 32.7 33.1 29.6 31.9 33.3 51.2 25.6 13.1 4.9 37.0 68.2 26.3 49.8 23.3 14.4 36.4 30.1 33.9 42.9 30.4 22.0 10.4 50.7 38.5 46.7 86.1 78.7 58.3 17.1 19.0 56.2 21.8 53.9 10.4 83.7 60.2 24.9 20.9 20.6 23.5 18.9 48.2 89.3 83.8 20.2 9.5 23.4 46.8 41.7 61.6 32.7 14.9 41.0 39.2 7.5 89.8 24.9 54.6 6.6 7.0 87.5 41.0 23.3 27.5 40.8 62.9 90.6 26.8 17.3 13.1 21.8 52.3 37.6 23.0 41.4 75.6 58.0 40.8 33.7 39.6 41.7 SMYD5 "NN8-4AG, RAI15, RRG1, ZMYND23" ENSG00000135632 "SMYD family member 5" Q6GMV2 2 73214222-73227221 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015514, HPA049002" Uncertain Approved Mitochondria NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA015514: AB_2669205, HPA049002: AB_2680595" "unprognostic (1.75e-1)" "unprognostic (3.39e-1)" "unprognostic (5.22e-2)" "unprognostic (6.66e-3)" "unprognostic (3.86e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (6.58e-7)" "unprognostic (1.28e-1)" "unprognostic (1.60e-2)" "unprognostic (3.84e-2)" "unprognostic (3.84e-1)" "unprognostic (2.49e-1)" "unprognostic (3.03e-2)" "unprognostic (3.94e-1)" "unprognostic (1.47e-1)" "unprognostic (1.91e-1)" "unprognostic (2.40e-1)" 13.3 19.1 27.2 12.1 27.8 11.6 14.8 24.3 30.5 15.5 22.0 12.5 7.3 14.4 19.4 14.1 19.5 7.3 17.9 28.2 28.0 18.8 15.2 9.8 13.1 28.9 26.5 28.3 18.4 17.9 15.4 13.1 28.8 15.4 11.3 13.0 12.2 13.4 17.7 14.5 12.4 14.5 25.9 16.2 11.4 17.4 26.9 8.2 14.3 13.0 16.0 17.5 13.1 26.9 24.3 45.2 27.0 25.9 19.3 28.4 45.7 22.8 23.0 43.4 26.6 59.4 24.4 43.1 20.9 38.6 52.1 24.4 42.2 49.4 39.1 26.3 29.7 41.8 19.5 65.9 26.0 41.5 16.5 24.0 31.4 39.7 47.3 19.2 26.7 33.9 44.9 20.2 27.9 34.1 38.8 27.1 42.2 50.8 36.3 25.6 50.6 35.5 28.6 34.6 17.4 25.9 20.7 30.7 26.4 24.4 25.0 14.7 18.5 29.7 46.3 36.5 38.1 22.0 17.7 38.2 33.5 35.2 24.3 0.0 1.4 0.0 5.1 3.9 11.1 6.0 7.0 6.8 3.2 6.2 7.0 7.7 0.0 4.5 4.3 3.0 3.1 4.5 27.2 27.8 24.3 30.5 28.2 28.0 28.9 26.5 28.8 25.9 26.9 26.9 4.1 3.2 5.6 5.2 5.6 5.1 3.9 2.3 1.8 10.2 5.4 6.7 7.2 2.8 4.4 5.5 4.2 9.0 3.4 2.4 1.9 8.5 0.5 2.8 4.2 4.9 0.0 9.5 5.0 8.8 10.4 4.5 2.6 3.7 7.0 9.5 2.9 4.8 5.9 5.0 5.2 4.4 4.1 2.4 2.5 2.9 2.8 2.7 5.4 2.8 3.7 4.0 4.1 1.5 3.5 5.6 1.5 3.0 3.1 5.0 1.3 8.1 1.3 5.3 6.6 4.0 4.6 6.7 11.1 5.7 3.4 4.8 4.5 4.6 5.6 3.6 SNX19 "CHET8, KIAA0254" ENSG00000120451 "Sorting nexin 19" Q92543 11 130866250-130916479 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 112.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013447 Uncertain Approved Mitochondria NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 35: Non-specific - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 46: Photoreceptor cells - Phototransduction" Mitochondria "HPA013447: AB_1857347" "unprognostic (8.79e-3)" "unprognostic (1.82e-1)" "unprognostic (1.45e-1)" "unprognostic (1.56e-1)" "unprognostic (2.97e-2)" "unprognostic (2.43e-1)" "unprognostic (4.17e-2)" "unprognostic (9.19e-2)" "unprognostic (3.43e-2)" "unprognostic (4.05e-2)" "unprognostic (2.89e-1)" "unprognostic (4.97e-2)" "prognostic favorable (3.56e-5)" "unprognostic (1.05e-1)" "unprognostic (2.77e-1)" "unprognostic (2.92e-2)" "unprognostic (1.55e-2)" 15.9 18.5 19.0 12.4 24.3 8.7 14.8 18.0 17.9 15.5 18.2 22.3 11.8 18.0 19.1 14.7 16.3 14.9 20.1 15.3 17.6 16.6 19.3 14.6 11.0 27.4 22.5 14.0 19.4 16.1 17.2 12.6 21.1 16.6 14.1 15.5 19.4 14.4 23.8 12.9 15.4 19.5 22.1 15.2 19.0 21.3 23.8 11.1 21.5 13.1 11.7 19.1 13.5 28.7 13.8 23.2 17.4 27.7 52.9 36.9 13.2 35.7 38.1 17.9 18.1 20.6 26.2 12.4 27.0 40.3 45.3 25.6 3.2 25.1 20.8 20.9 13.7 24.3 18.3 0.1 30.9 0.0 19.1 42.1 24.4 20.0 17.9 35.3 20.9 17.9 23.5 0.1 35.3 10.9 18.6 10.6 4.9 30.0 19.3 16.1 17.2 8.0 11.9 27.8 19.6 16.4 16.7 22.4 11.1 13.4 46.6 13.0 34.4 26.7 20.9 21.8 21.3 4.5 0.0 0.1 9.7 13.5 28.9 6.5 3.6 2.5 2.1 3.2 3.0 2.8 1.9 2.5 2.9 1.8 2.3 2.0 1.7 1.6 4.0 2.7 1.9 3.5 19.0 24.3 18.0 17.9 15.3 17.6 27.4 22.5 21.1 22.1 23.8 28.7 12.6 25.6 7.9 44.4 14.8 4.0 7.2 7.8 8.6 25.6 11.6 9.1 20.4 15.7 12.9 23.9 10.4 10.3 10.0 19.4 9.8 11.5 35.8 10.8 14.3 12.2 11.4 7.4 30.0 16.0 5.7 11.4 15.8 11.0 18.4 13.5 13.9 21.3 10.1 16.8 34.9 12.5 6.1 11.7 5.2 44.7 13.7 11.9 3.6 20.6 9.6 22.4 13.4 35.7 112.6 16.6 14.5 15.8 15.5 10.2 14.4 8.6 16.9 37.9 13.1 12.7 9.8 37.1 15.5 9.8 4.3 14.0 9.2 13.1 10.3 10.8 SOD2 GClnc1 ENSG00000112096 "Superoxide dismutase 2" P04179 6 159669069-159762529 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 1083.7;skeletal muscle: 3230.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 2508.2;Prostatic glandular cells: 3524.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 10 "neutrophil: 4470.5" "Lineage enriched" "Detected in all" 10 "granulocytes: 4470.5" "Cell line enhanced" "Detected in all" "BJ hTERT+: 1611.9;GAMG: 614.3;HSkMC: 688.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001814, CAB002013" Supported Enhanced Mitochondria NA NA 55000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" Mitochondria "CAB002013: , HPA001814: AB_1080134" "unprognostic (2.47e-2)" "unprognostic (2.77e-3)" "unprognostic (1.14e-1)" "unprognostic (1.57e-2)" "unprognostic (1.31e-1)" "unprognostic (1.69e-1)" "unprognostic (1.49e-1)" "unprognostic (3.10e-2)" "unprognostic (1.37e-1)" "unprognostic (6.67e-2)" "unprognostic (2.76e-2)" "unprognostic (7.14e-2)" "prognostic unfavorable (1.72e-4)" "unprognostic (8.12e-2)" "unprognostic (4.14e-2)" "unprognostic (5.99e-2)" "unprognostic (1.82e-1)" 324.8 245.9 66.8 522.8 43.2 1083.7 169.0 37.8 125.8 92.6 99.7 126.4 60.5 105.4 7.2 136.5 118.5 121.8 178.5 37.0 101.0 252.4 459.8 266.5 64.8 250.0 96.1 55.8 212.3 69.1 42.7 62.9 192.9 130.8 37.9 25.1 328.8 43.9 3230.1 90.0 83.7 108.4 62.5 81.4 120.4 39.6 153.1 38.2 67.2 312.6 65.0 514.9 97.9 85.4 35.8 46.3 37.3 85.1 229.0 378.7 20.5 52.7 1611.9 57.7 131.1 91.3 19.4 70.7 144.5 54.1 614.3 58.9 39.1 42.5 42.4 71.2 87.2 74.5 71.8 152.3 169.5 74.0 31.9 688.9 68.5 180.9 133.6 40.7 30.0 44.9 106.7 82.2 55.4 37.6 60.3 46.6 63.3 41.5 55.4 79.6 50.3 63.9 106.2 56.6 71.5 29.5 105.1 52.4 21.4 14.1 33.1 33.7 30.4 168.6 62.1 92.5 87.9 37.8 100.2 86.5 186.7 57.4 23.6 146.3 364.4 181.1 38.8 273.9 43.4 43.4 54.9 38.5 105.2 38.3 45.0 36.9 4470.5 19.1 445.3 14.8 87.9 340.0 66.8 43.2 37.8 125.8 37.0 101.0 250.0 96.1 192.9 62.5 153.1 85.4 303.2 201.9 746.1 13.4 99.0 684.7 1144.9 2508.2 114.4 45.6 150.2 96.6 0.0 287.4 613.3 237.3 45.9 18.3 43.8 153.9 86.1 1400.2 318.2 281.7 649.8 593.0 79.6 101.2 31.1 1389.7 51.2 1098.4 103.5 1080.1 112.3 23.1 58.9 395.0 292.0 32.0 30.1 92.7 339.7 333.3 1425.8 111.5 58.1 1031.2 521.2 15.9 339.9 50.4 35.0 8.5 12.2 581.6 111.3 65.1 101.2 3524.0 128.6 530.1 269.6 61.8 39.5 1164.0 407.3 91.7 51.4 258.7 681.8 27.2 119.4 38.3 148.1 1195.7 SP9 ZNF990 ENSG00000217236 "Sp9 transcription factor" P0CG40 2 174334954-174338500 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 3.2" "Cell type enriched" "Detected in some" 5 "Inhibitory neurons: 11.1" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 7.2;fHDF/TERT166: 5.5;HEK 293: 2.2;THP-1: 11.6" "Group enriched" "Detected in many" 6 "basal ganglia: 5.8;olfactory bulb: 11.7" "Group enriched" "Detected in many" 4 "basal ganglia: 5.6;olfactory bulb: 21.6" HPA062616 Uncertain Approved Mitochondria NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA062616: AB_2684808" "unprognostic (2.04e-2)" "unprognostic (6.94e-3)" "unprognostic (1.44e-1)" "unprognostic (3.95e-1)" "unprognostic (7.55e-3)" "unprognostic (8.54e-2)" "unprognostic (3.12e-1)" "unprognostic (1.01e-1)" 0.0 0.0 2.5 0.0 2.9 0.0 0.2 0.0 3.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.7 1.6 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.2 7.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 5.5 0.0 0.1 0.2 0.0 0.0 0.0 2.2 0.5 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.1 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 1.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 2.9 0.0 3.2 0.7 1.6 0.1 0.3 0.1 0.0 0.6 0.4 0.2 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 1.3 0.5 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.7 0.5 0.0 0.1 0.0 0.1 0.1 0.0 0.0 SPACA9 "C9orf9, Mast" ENSG00000165698 "Sperm acrosome associated 9" Q96E40 9 132878027-132890201 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 74.0;testis: 131.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 23.9;Distal tubular cells: 33.2;Endometrial ciliated cells: 99.8;Proximal tubular cells: 23.9;Respiratory ciliated cells: 63.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 4 "JURKAT: 48.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA022243, HPA051600" Enhanced Approved Mitochondria No No "Cluster 19: B-cells - Humoral immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" Mitochondria "HPA022243: AB_1845844, HPA051600: AB_2681546" "unprognostic (2.69e-1)" "unprognostic (2.14e-3)" "unprognostic (8.00e-3)" "prognostic favorable (8.61e-4)" "unprognostic (1.59e-1)" "unprognostic (5.73e-2)" "unprognostic (3.76e-3)" "unprognostic (2.60e-1)" "unprognostic (6.43e-2)" "unprognostic (1.12e-1)" "unprognostic (1.15e-2)" "unprognostic (9.51e-2)" "prognostic favorable (8.31e-4)" "unprognostic (5.11e-2)" "unprognostic (1.22e-2)" "unprognostic (1.20e-1)" "unprognostic (1.22e-2)" 5.0 7.6 17.4 1.3 17.7 1.5 5.2 17.4 19.5 9.7 18.2 11.5 1.3 8.3 74.0 9.5 39.2 5.4 10.4 16.8 19.0 12.2 2.3 7.4 2.2 20.3 22.2 11.3 5.2 3.8 11.5 3.2 19.1 7.0 1.9 8.2 9.8 7.1 1.7 11.9 3.7 4.9 21.3 3.6 6.5 131.2 18.5 7.9 15.6 1.8 3.2 6.1 8.1 19.0 3.0 3.2 4.8 3.9 6.6 8.4 5.7 1.9 3.5 2.6 2.8 0.8 9.1 0.7 4.3 8.7 5.4 4.2 2.0 5.4 2.3 3.5 3.9 0.8 2.3 1.0 9.6 2.2 0.3 9.6 11.4 6.4 6.9 10.6 3.0 48.5 0.8 2.4 7.1 6.4 7.6 8.6 1.0 5.6 3.0 3.6 1.0 2.1 10.5 1.1 1.2 4.7 8.0 1.3 6.3 3.6 10.3 0.7 2.9 5.5 3.7 5.3 0.8 1.0 1.7 2.6 10.2 0.8 2.7 4.0 1.1 1.9 1.1 1.1 1.3 3.0 1.2 0.6 1.6 2.6 1.3 1.3 1.5 4.4 1.9 0.5 2.0 0.9 17.4 17.7 17.4 19.5 16.8 19.0 20.3 22.2 19.1 21.3 18.5 19.0 3.6 3.2 2.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 10.3 17.9 0.0 0.0 5.0 23.9 0.0 18.2 0.8 0.0 33.2 8.6 0.0 99.8 7.1 1.9 0.0 0.0 0.0 7.1 12.4 3.9 0.0 8.1 0.0 6.7 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 23.9 63.4 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 7.3 0.8 7.7 0.0 0.0 SPATA18 FLJ32906 ENSG00000163071 "Spermatogenesis associated 18" Q8TC71 4 52051304-52097299 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 68.3;testis: 28.8" "Cell type enriched" "Detected in many" 4 "Late spermatids: 2341.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 31.5;BEWO: 24.4;BJ hTERT+: 15.9;HSkMC: 29.3;hTCEpi: 28.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA036854, HPA036855" Enhanced Supported Mitochondria NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 28: BEWO - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "HPA036854: AB_10670927, HPA036855: AB_2675352" "unprognostic (6.54e-2)" "unprognostic (1.90e-1)" "unprognostic (1.46e-1)" "prognostic favorable (1.32e-5)" "unprognostic (1.02e-2)" "unprognostic (1.53e-2)" "unprognostic (7.27e-2)" "unprognostic (4.49e-2)" "unprognostic (1.76e-1)" "unprognostic (2.73e-1)" "unprognostic (3.13e-1)" "unprognostic (3.13e-2)" "prognostic favorable (3.73e-9)" "unprognostic (4.38e-1)" "unprognostic (1.39e-1)" "unprognostic (1.01e-2)" "unprognostic (4.00e-2)" 2.1 5.0 2.4 0.7 2.2 0.0 6.3 1.3 1.0 10.7 15.6 4.1 2.1 4.2 2.0 4.6 68.3 6.7 1.8 2.5 2.7 5.3 5.4 8.0 0.3 6.8 8.3 1.8 2.0 4.5 4.9 1.9 5.5 4.2 5.6 0.1 10.1 5.6 0.8 6.6 2.2 3.1 6.0 0.6 4.9 28.8 2.6 3.2 1.2 1.3 0.9 2.8 3.4 3.8 0.0 3.8 1.8 0.0 12.7 31.5 24.4 9.3 15.9 0.6 0.7 0.0 1.5 0.0 0.0 12.3 0.2 0.3 0.1 7.1 0.3 0.0 1.1 0.0 0.0 8.0 11.2 0.0 0.0 29.3 28.7 1.0 4.5 5.1 6.9 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.9 2.0 1.0 0.0 0.0 9.7 0.0 0.2 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 2.2 1.3 1.0 2.5 2.7 6.8 8.3 5.5 6.0 2.6 3.8 0.3 9.6 3.0 0.3 0.0 5.2 8.5 9.4 8.6 0.0 6.0 6.7 2.2 8.6 15.1 0.0 0.0 1.7 0.3 1.8 1.9 1.2 561.1 124.6 1.8 1.2 1.8 0.0 1.7 2.6 1.8 4.3 11.2 4.7 2.5 1.9 1.4 3.4 0.3 0.0 0.5 1.6 6.1 0.6 1.6 2341.5 10.8 1.1 0.0 2.8 0.1 0.0 0.0 0.5 0.1 2.0 2.7 10.9 0.0 5.1 1.9 7.4 141.4 0.0 0.0 1.8 3.9 13.9 7.1 7.1 7.5 0.8 0.2 2.5 4.3 6.8 SPATA9 "FLJ35906, NYD-SP16" ENSG00000145757 "Spermatogenesis associated 9" Q9BWV2 5 95652181-95698711 "Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "testis: 26.7" "Group enriched" "Detected in some" 18 "Early spermatids: 580.3;Late spermatids: 498.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "K-562: 1.0;THP-1: 1.1" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA010848, HPA076967" Approved Approved Mitochondria NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 74: Testis - Spermatogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 34: Spermatids - Unknown function" Mitochondria "HPA010848: AB_1857422, HPA076967: " "unprognostic (4.46e-2)" "unprognostic (4.02e-2)" "unprognostic (1.37e-1)" "unprognostic (1.22e-1)" "unprognostic (9.60e-2)" "unprognostic (5.69e-2)" "unprognostic (1.33e-2)" "unprognostic (2.08e-1)" "unprognostic (3.27e-2)" "unprognostic (7.58e-2)" "unprognostic (1.28e-2)" "unprognostic (3.08e-2)" "unprognostic (9.49e-13)" "unprognostic (3.39e-1)" "unprognostic (2.37e-1)" "unprognostic (1.26e-2)" "unprognostic (2.87e-2)" 1.1 0.3 0.1 0.1 0.2 0.2 0.2 0.4 0.3 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.0 0.2 0.2 0.2 0.4 0.3 0.0 0.0 0.2 0.2 0.1 0.1 0.1 0.2 0.0 0.1 0.4 0.1 0.0 0.1 0.2 0.0 26.7 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.8 0.0 0.0 0.0 0.1 0.2 0.7 0.0 0.0 0.1 0.1 0.2 0.3 0.0 0.1 0.0 0.3 0.1 0.2 1.0 0.0 0.5 0.0 0.2 0.7 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.0 1.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.4 0.3 0.1 0.3 0.2 0.2 0.2 0.1 0.2 0.6 0.0 0.0 0.0 3.6 0.0 0.0 0.1 0.1 0.0 0.4 0.4 0.0 0.4 0.0 0.1 0.0 0.0 0.9 0.3 0.0 0.0 0.1 580.3 0.3 0.5 0.2 0.0 0.0 1.9 0.0 29.2 0.4 0.0 0.2 0.0 0.9 0.0 0.1 1.3 1.7 2.6 0.1 0.0 0.3 0.0 498.7 3.7 0.2 0.0 3.7 0.1 0.5 2.1 14.1 1.7 0.0 0.4 3.4 0.1 0.3 0.1 0.0 0.2 0.4 0.0 1.7 0.3 7.7 3.2 0.0 0.1 4.2 0.1 0.6 0.2 0.2 SPSB3 "C16orf31, SSB-3" ENSG00000162032 "SplA/ryanodine receptor domain and SOCS box containing 3" Q6PJ21 16 1776712-1793700 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046602 Uncertain Approved Mitochondria NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA046602: AB_2679717" "unprognostic (1.18e-1)" "unprognostic (2.37e-2)" "unprognostic (1.79e-1)" "unprognostic (1.15e-3)" "unprognostic (1.82e-1)" "unprognostic (8.91e-4)" "unprognostic (1.07e-2)" "unprognostic (8.31e-2)" "unprognostic (5.65e-2)" "unprognostic (8.43e-2)" "unprognostic (3.41e-2)" "unprognostic (4.83e-2)" "unprognostic (5.25e-7)" "unprognostic (2.16e-2)" "unprognostic (2.02e-1)" "unprognostic (3.77e-1)" "unprognostic (4.72e-4)" 27.1 44.7 27.9 7.7 28.5 21.2 25.8 37.0 40.2 27.1 24.0 28.9 14.7 21.3 3.3 36.1 23.7 10.0 28.6 26.4 27.2 24.3 41.8 20.6 12.4 29.7 28.3 37.1 44.0 11.4 15.3 10.3 27.4 23.3 5.1 9.6 26.4 15.5 88.5 48.4 18.8 5.6 28.3 23.3 27.8 17.3 29.2 26.1 19.7 31.0 7.8 23.2 28.7 31.8 7.3 9.1 9.7 13.4 13.6 12.5 19.8 10.6 11.0 11.5 12.6 8.4 20.0 3.2 17.4 6.0 4.5 13.9 4.8 10.9 1.8 14.7 15.0 5.2 13.9 10.4 20.2 4.5 12.0 11.3 26.8 7.2 8.4 17.1 17.5 22.1 7.8 15.4 5.4 24.0 16.3 16.0 8.1 10.8 7.1 29.7 5.9 26.7 10.6 1.3 12.9 16.6 12.6 27.8 29.4 6.9 16.1 18.0 16.1 5.6 10.6 10.5 5.5 26.1 28.2 8.9 5.4 8.9 5.9 112.3 44.8 83.4 67.9 41.8 81.2 46.8 63.1 61.7 42.3 44.2 43.6 46.6 91.5 45.7 37.2 42.8 100.7 48.4 27.9 28.5 37.0 40.2 26.4 27.2 29.7 28.3 27.4 28.3 29.2 31.8 74.2 38.5 32.1 29.7 56.1 98.4 53.3 72.7 60.3 74.1 64.1 83.7 0.2 40.0 54.9 55.2 39.6 63.0 104.2 68.6 52.8 50.8 46.7 29.4 32.3 46.1 48.7 50.5 18.2 47.6 74.8 42.8 65.2 37.8 35.4 76.2 57.1 62.5 31.8 90.9 19.4 57.8 38.7 42.7 72.2 91.6 77.0 44.8 76.5 24.4 61.6 76.0 99.9 24.6 30.7 45.3 83.2 74.9 61.2 50.5 96.3 50.6 37.2 89.8 39.5 34.0 45.3 23.8 39.7 37.0 128.3 64.4 87.8 33.2 52.7 54.3 SQOR "CGI-44, SQR, SQRDL" ENSG00000137767 "Sulfide quinone oxidoreductase" Q9Y6N5 15 45631148-45691281 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 210.0" "Cell type enhanced" "Detected in many" "Ductal cells: 118.1;Exocrine glandular cells: 176.2;Hofbauer cells: 134.3;monocytes: 154.5;Pancreatic endocrine cells: 156.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HBEC3-KT: 304.0" "HPA017079, HPA041589" Enhanced Supported Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA017079: AB_1857467, HPA041589: AB_2677565" "unprognostic (6.15e-2)" "unprognostic (3.28e-2)" "unprognostic (2.15e-1)" "prognostic favorable (2.57e-4)" "unprognostic (2.75e-2)" "unprognostic (5.51e-2)" "unprognostic (6.68e-3)" "prognostic unfavorable (8.80e-4)" "unprognostic (1.81e-1)" "unprognostic (3.77e-1)" "unprognostic (6.65e-3)" "unprognostic (2.37e-1)" "unprognostic (3.14e-3)" "unprognostic (2.29e-1)" "unprognostic (4.92e-2)" "unprognostic (7.44e-2)" "unprognostic (4.38e-1)" 46.4 22.6 14.5 59.5 14.6 55.6 41.2 14.6 19.7 36.3 17.2 210.0 57.7 18.8 19.3 112.9 26.6 31.4 22.0 13.6 14.7 36.6 82.6 61.5 38.2 16.7 15.1 8.8 39.8 24.1 12.5 17.6 15.6 41.2 178.8 4.9 56.3 27.8 132.8 41.7 55.9 43.2 15.9 47.3 54.4 5.1 15.8 23.7 32.5 43.7 57.7 48.8 50.3 17.2 38.3 68.0 0.1 3.9 125.5 151.4 0.4 40.8 132.3 23.6 35.7 2.7 59.0 33.7 38.7 29.9 72.6 33.3 2.0 304.0 13.9 121.7 1.1 3.0 14.5 48.2 38.8 20.2 5.1 45.2 88.2 54.9 119.8 59.4 66.1 32.0 0.4 40.6 24.6 31.3 12.2 44.9 0.0 147.7 41.8 1.4 6.7 47.1 184.9 55.2 1.2 1.2 10.1 25.8 13.1 0.8 56.9 61.7 76.8 9.7 2.2 131.6 9.0 53.5 61.0 2.0 96.9 104.6 10.9 112.5 212.1 84.6 76.6 161.0 104.6 54.3 97.9 83.6 135.2 48.6 51.8 55.2 302.5 53.4 152.4 40.5 149.0 169.6 14.5 14.6 14.6 19.7 13.6 14.7 16.7 15.1 15.6 15.9 15.8 17.2 24.4 32.1 64.1 0.0 5.8 0.0 0.0 0.0 0.0 0.0 31.4 14.7 0.0 0.0 14.9 14.7 0.0 0.7 19.8 0.0 11.7 118.1 0.0 15.9 7.0 13.9 0.0 0.0 0.0 176.2 0.9 11.3 0.0 37.6 11.4 1.3 0.0 0.0 134.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.3 0.0 0.0 154.5 0.0 0.0 0.0 0.0 156.2 0.0 0.0 3.3 0.0 0.0 45.8 24.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 0.8 13.5 1.6 0.0 0.0 SSBP1 "mtSSB, SSBP" ENSG00000106028 "Single stranded DNA binding protein 1" Q04837 7 141738334-141787922 "Human disease related genes, Predicted intracellular proteins" "DNA replication" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002866 Supported Supported Mitochondria NA NA 150000 "Cluster 44: Non-specific - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Mitochondria "HPA002866: AB_1080092" "unprognostic (2.95e-1)" "unprognostic (2.99e-1)" "unprognostic (2.49e-2)" "unprognostic (3.62e-2)" "unprognostic (7.36e-3)" "unprognostic (2.86e-2)" "prognostic unfavorable (4.42e-4)" "unprognostic (3.68e-2)" "unprognostic (6.03e-2)" "prognostic favorable (3.40e-4)" "unprognostic (9.23e-3)" "unprognostic (4.02e-1)" "unprognostic (9.65e-3)" "unprognostic (1.62e-1)" "unprognostic (9.38e-2)" "unprognostic (1.25e-2)" "unprognostic (9.58e-2)" 86.1 105.0 70.5 80.9 72.6 89.9 97.0 72.3 101.1 75.1 65.8 94.1 70.4 83.6 107.7 125.9 74.0 54.0 135.0 71.5 74.5 105.4 120.4 62.9 97.0 72.5 74.4 85.3 87.8 93.6 64.8 78.4 72.8 64.9 85.3 58.2 77.4 70.4 141.2 88.4 77.5 76.1 72.5 80.8 93.1 80.8 70.8 96.6 82.7 94.1 112.8 91.8 82.1 74.4 280.6 333.6 281.6 369.2 125.5 193.2 262.2 208.7 193.0 256.4 287.9 353.7 330.5 414.0 267.6 173.5 421.8 210.2 349.5 347.4 369.6 220.8 339.1 226.1 253.6 322.3 242.6 644.9 166.8 179.9 230.9 257.4 373.0 177.7 316.2 279.9 552.8 184.0 343.4 430.9 477.3 837.2 634.1 476.8 403.0 262.6 258.2 578.5 340.9 286.7 256.4 352.5 236.8 323.7 319.8 213.7 210.7 267.2 239.6 183.0 171.6 282.1 533.8 328.6 465.9 796.1 369.9 577.6 395.8 136.1 69.9 76.8 71.7 96.1 107.7 106.3 113.8 98.9 90.6 92.0 101.1 113.7 20.6 98.8 99.8 104.0 123.8 116.3 70.5 72.6 72.3 101.1 71.5 74.5 72.5 74.4 72.8 72.5 70.8 74.4 151.0 102.5 104.7 13.7 135.7 116.0 199.6 477.7 98.4 58.6 114.3 178.8 279.1 148.7 242.7 150.8 41.7 311.0 139.2 92.7 350.2 310.3 187.0 160.6 162.3 136.5 96.3 111.7 17.0 353.3 313.7 140.5 92.2 169.8 151.9 163.3 105.3 221.9 251.9 43.7 16.0 163.7 244.1 122.0 126.3 62.2 137.3 131.0 104.9 15.0 221.2 152.1 157.6 16.6 29.1 314.0 130.0 123.8 101.3 166.6 141.9 445.2 178.0 79.1 98.6 170.6 223.5 253.5 190.0 136.3 129.4 261.7 145.2 254.1 188.1 200.2 STARD7 GTT1 ENSG00000084090 "StAR related lipid transfer domain containing 7" Q9NQZ5 2 96184859-96208827 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033965, HPA064958, HPA064978" Supported Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "CAB033965: AB_2302780, HPA064958: AB_2685391, HPA064978: AB_2685397" "unprognostic (3.75e-2)" "unprognostic (1.54e-2)" "unprognostic (1.67e-1)" "prognostic unfavorable (8.56e-5)" "prognostic favorable (3.89e-6)" "unprognostic (1.51e-1)" "prognostic unfavorable (2.22e-4)" "unprognostic (2.72e-3)" "unprognostic (2.38e-1)" "unprognostic (2.93e-1)" "unprognostic (4.66e-2)" "unprognostic (1.78e-1)" "prognostic favorable (4.38e-6)" "unprognostic (1.02e-1)" "unprognostic (2.04e-1)" "unprognostic (2.64e-2)" "unprognostic (2.42e-2)" 44.7 54.3 57.8 46.7 62.4 34.3 43.9 61.9 53.2 33.9 60.6 57.6 55.7 29.8 30.5 36.8 44.0 29.1 98.5 49.8 61.4 80.3 62.8 61.1 70.6 56.4 55.5 29.4 42.2 69.7 23.6 29.3 54.9 39.0 56.2 54.4 65.2 45.7 202.5 35.2 45.4 37.6 60.5 53.1 44.6 21.1 66.9 56.2 56.6 174.0 86.9 42.1 27.0 74.4 128.8 79.1 102.3 106.2 134.9 66.9 150.1 122.6 107.0 121.2 129.6 188.8 117.7 228.7 129.0 98.6 95.8 102.3 183.3 106.4 157.3 147.2 131.9 204.1 74.3 218.3 62.2 158.1 106.9 65.4 77.9 101.0 99.1 77.2 123.2 92.6 211.1 89.2 108.8 113.0 175.9 161.0 173.3 110.3 115.2 171.6 156.4 227.1 73.2 162.2 191.6 90.5 62.5 201.8 115.8 126.0 60.5 171.6 103.8 100.1 100.4 112.0 125.8 113.9 114.0 201.7 92.8 174.9 112.6 35.6 25.4 22.7 25.6 30.2 26.1 42.6 21.5 26.6 36.2 37.8 23.6 23.4 3.0 30.8 19.9 42.2 41.5 26.0 57.8 62.4 61.9 53.2 49.8 61.4 56.4 55.5 54.9 60.5 66.9 74.4 32.0 134.6 44.2 21.5 71.2 63.7 43.2 34.3 101.9 39.5 58.1 50.2 176.9 55.8 47.1 46.0 108.4 35.8 83.8 63.3 74.3 32.4 2.5 34.5 43.2 49.9 44.4 48.6 25.6 38.0 40.3 31.3 37.8 48.6 15.8 45.4 41.7 114.7 71.0 40.4 23.8 58.4 24.4 122.4 102.3 6.9 23.3 54.4 42.7 20.6 95.8 38.4 30.9 19.1 42.6 35.8 26.6 25.2 120.6 68.4 50.1 65.7 31.8 58.1 26.3 43.5 43.0 22.7 35.1 75.4 57.4 35.4 62.9 36.8 81.9 38.8 STMP1 "C7orf73, Mm47, PL-5283" ENSG00000243317 "Short transmembrane mitochondrial protein 1" E0CX11 7 135662496-135693418 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 249.0;Distal tubular cells: 197.6;Extravillous trophoblasts: 261.3;Hofbauer cells: 185.2;Proximal tubular cells: 209.5;Syncytiotrophoblasts: 275.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 431.7;eosinophil: 127.7" "Lineage enriched" "Detected in all" 6 "granulocytes: 431.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065565 Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA065565: AB_2685512" "unprognostic (3.94e-2)" "unprognostic (1.05e-1)" "unprognostic (8.76e-2)" "unprognostic (3.11e-2)" "unprognostic (3.64e-2)" "unprognostic (1.81e-1)" "unprognostic (2.99e-3)" "unprognostic (1.12e-1)" "unprognostic (4.43e-3)" "prognostic favorable (2.95e-4)" "unprognostic (1.93e-1)" "unprognostic (1.30e-1)" "unprognostic (7.21e-3)" "unprognostic (4.90e-2)" "unprognostic (9.99e-2)" "unprognostic (9.62e-3)" "unprognostic (6.81e-2)" 15.7 28.5 15.5 17.7 17.3 41.3 22.9 15.8 20.5 21.1 17.9 19.8 18.2 16.1 25.7 46.7 15.9 16.6 25.4 15.2 17.2 27.9 32.0 15.2 21.2 17.6 16.4 12.9 15.1 18.5 19.0 19.8 18.1 20.3 22.5 19.2 21.0 15.0 48.4 21.5 19.2 16.4 16.9 14.7 20.4 23.8 16.6 28.8 32.2 32.8 26.2 20.0 27.4 17.6 41.5 19.4 44.9 42.4 52.6 73.2 27.3 44.8 43.5 36.3 37.8 12.0 45.2 38.3 39.3 68.7 35.6 17.0 43.9 57.0 48.9 48.2 36.1 59.4 20.4 28.8 51.7 61.3 36.8 46.0 63.6 43.6 40.4 54.9 30.5 48.5 65.3 33.0 80.9 54.0 87.6 69.5 88.6 57.4 48.5 43.6 48.0 63.0 102.2 21.5 56.6 54.7 60.8 41.3 43.9 43.1 16.9 66.0 51.1 35.3 29.0 63.5 63.2 38.1 58.5 72.9 109.1 63.1 65.9 431.7 57.3 127.7 23.8 61.2 22.8 24.9 22.5 24.3 61.0 21.0 21.0 24.1 44.6 38.9 68.1 34.5 33.1 50.9 15.5 17.3 15.8 20.5 15.2 17.2 17.6 16.4 18.1 16.9 16.6 17.6 67.4 41.7 47.0 0.0 20.7 0.0 0.0 0.0 0.0 0.0 128.9 145.3 0.0 0.0 27.9 97.5 0.0 249.0 57.2 0.0 197.6 164.3 0.0 102.2 97.3 39.4 0.0 0.0 0.0 97.4 261.3 43.9 0.0 90.8 56.8 80.1 0.0 0.0 185.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 64.7 0.0 0.0 146.8 0.0 0.0 0.0 0.0 131.8 0.0 0.0 6.4 0.0 0.0 209.5 34.2 0.0 0.0 0.0 53.0 0.0 0.0 0.0 0.0 275.4 29.8 65.8 0.0 0.0 SUCLA2 LINC00444 ENSG00000136143 "Succinate-CoA ligase ADP-forming subunit beta" Q9P2R7 13 47745736-48037968 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Ligase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 232.2;tongue: 271.9" "Cell type enhanced" "Detected in all" "Early spermatids: 256.2;Late spermatids: 314.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039435, HPA039536, HPA061528" Enhanced Supported Enhanced Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA039435: AB_10673144, HPA039536: AB_2676561, HPA061528: AB_2684553" "unprognostic (5.66e-3)" "unprognostic (1.72e-2)" "unprognostic (1.14e-1)" "unprognostic (8.76e-2)" "unprognostic (1.60e-1)" "unprognostic (3.45e-2)" "unprognostic (2.48e-1)" "unprognostic (1.71e-1)" "unprognostic (4.70e-2)" "unprognostic (1.41e-2)" "unprognostic (1.10e-1)" "unprognostic (1.38e-1)" "prognostic favorable (7.59e-14)" "unprognostic (3.53e-1)" "unprognostic (2.19e-1)" "unprognostic (2.29e-1)" "prognostic unfavorable (1.22e-4)" 53.9 40.6 28.4 20.2 30.8 13.6 38.7 36.6 39.2 32.4 33.6 37.1 58.2 27.2 24.8 33.1 24.7 20.3 100.2 30.7 38.2 77.5 29.0 18.2 22.0 30.6 30.0 30.9 25.4 71.2 20.4 28.1 32.3 35.8 36.3 44.2 33.9 31.3 232.2 20.5 44.7 33.1 30.6 19.9 29.7 17.9 33.8 30.7 36.4 271.9 23.9 26.0 25.3 35.1 44.9 49.5 60.6 37.1 68.4 51.3 38.9 64.8 72.4 66.9 44.5 91.3 47.9 61.3 49.3 63.9 39.9 60.0 81.9 61.9 81.6 59.8 75.9 69.2 45.8 58.0 47.6 69.9 38.9 48.4 71.2 45.3 52.6 54.4 49.0 70.7 47.7 21.1 65.8 31.4 73.1 80.8 64.4 150.2 64.7 60.9 55.4 49.3 94.4 41.9 34.7 41.2 54.5 49.3 39.1 66.5 43.8 60.8 39.0 36.2 24.1 53.0 45.7 23.0 37.4 72.7 22.8 50.9 54.8 12.6 50.2 27.8 34.4 53.7 41.9 34.6 38.0 42.2 62.5 33.1 47.7 47.5 8.8 51.8 46.1 49.8 46.6 36.5 28.4 30.8 36.6 39.2 30.7 38.2 30.6 30.0 32.3 30.6 33.8 35.1 20.8 25.6 16.8 17.6 20.1 32.4 37.7 57.5 21.1 44.8 28.9 26.5 148.8 17.2 40.2 31.3 12.5 48.7 18.1 29.1 164.4 32.3 256.2 50.9 32.0 22.0 19.2 21.0 37.0 17.8 42.7 37.7 19.9 52.6 33.7 25.2 16.1 14.7 29.9 45.4 39.0 19.5 71.2 16.7 20.4 314.2 37.0 21.7 42.7 21.5 24.9 43.3 13.4 26.2 38.2 20.2 30.6 46.3 22.1 35.9 62.3 127.4 29.9 42.4 39.5 33.3 50.0 36.3 29.0 22.8 31.7 52.1 19.7 47.3 30.4 39.0 SUPV3L1 SUV3 ENSG00000156502 "Suv3 like RNA helicase" Q8IYB8 10 69180234-69209099 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038380, HPA038405" Supported Supported Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Mitochondria "HPA038380: AB_2675983, HPA038405: AB_10675797" "unprognostic (4.70e-2)" "unprognostic (1.85e-2)" "unprognostic (2.25e-1)" "unprognostic (1.19e-2)" "unprognostic (3.74e-2)" "unprognostic (3.32e-2)" "unprognostic (1.44e-2)" "unprognostic (1.78e-1)" "unprognostic (1.57e-1)" "unprognostic (9.47e-3)" "unprognostic (1.70e-1)" "unprognostic (1.06e-1)" "unprognostic (5.48e-3)" "unprognostic (5.03e-2)" "unprognostic (1.61e-1)" "unprognostic (5.27e-2)" "unprognostic (1.33e-1)" 10.1 10.9 7.9 8.7 8.2 24.2 11.5 10.2 10.3 7.7 7.6 11.6 8.9 9.3 7.9 8.8 8.3 6.0 15.8 8.5 8.2 12.9 17.9 6.1 12.0 7.9 7.4 10.6 9.3 16.5 7.5 8.7 7.9 8.0 12.7 11.1 8.9 8.6 25.9 10.6 8.6 9.3 7.2 9.9 8.9 15.8 7.8 11.0 10.9 29.1 12.2 9.5 7.7 8.5 28.9 19.9 17.4 53.5 19.1 16.1 22.7 17.5 27.1 34.7 32.6 51.4 23.8 51.5 14.0 17.6 24.8 32.3 42.2 27.4 33.1 21.5 33.1 22.6 14.9 27.2 48.1 54.3 16.5 20.5 33.7 31.9 72.6 23.6 20.3 32.2 59.6 26.1 19.2 18.7 33.1 33.5 20.8 27.2 106.7 30.1 24.7 22.6 15.6 13.9 24.7 18.7 24.2 49.7 46.7 19.1 15.5 23.5 12.7 13.7 24.7 21.1 34.3 20.5 25.4 47.5 22.6 56.4 8.9 8.9 5.1 4.7 11.1 7.3 12.5 9.0 7.9 9.5 7.1 7.3 8.7 9.6 0.9 7.7 5.4 3.9 8.8 6.2 7.9 8.2 10.2 10.3 8.5 8.2 7.9 7.4 7.9 7.2 7.8 8.5 11.2 6.4 7.4 15.3 21.7 23.8 11.6 16.6 21.6 21.6 10.8 9.5 22.5 5.7 15.1 7.3 4.2 17.8 49.3 11.7 11.7 11.6 13.4 17.2 17.6 10.1 9.0 10.3 29.6 8.6 11.4 12.6 14.8 28.8 7.6 15.1 5.7 12.0 9.6 11.8 28.2 9.0 16.2 6.0 10.0 4.5 6.8 9.4 5.4 15.0 7.2 11.3 19.6 14.1 17.6 8.5 8.1 9.1 37.0 10.8 8.5 14.3 12.6 12.5 6.6 17.2 14.6 38.6 26.6 23.6 22.3 22.4 28.8 16.1 14.1 10.7 SUV39H2 "FLJ23414, KMT1B" ENSG00000152455 "Suppressor of variegation 3-9 homolog 2" Q9H5I1 10 14878820-14904315 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Differentiation, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "testis: 39.3" "Cell type enriched" "Detected in many" 4 "Early spermatids: 421.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045901, HPA057554" Enhanced Uncertain Mitochondria NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" Mitochondria "HPA045901: AB_10960702, HPA057554: AB_2683466" "prognostic unfavorable (5.55e-4)" "unprognostic (1.45e-1)" "unprognostic (2.98e-2)" "unprognostic (8.78e-3)" "unprognostic (6.80e-2)" "unprognostic (1.23e-3)" "prognostic unfavorable (2.01e-6)" "unprognostic (1.06e-1)" "unprognostic (9.15e-2)" "unprognostic (3.59e-3)" "unprognostic (2.42e-1)" "unprognostic (4.13e-3)" "prognostic unfavorable (5.71e-5)" "unprognostic (2.71e-2)" "unprognostic (1.40e-1)" "unprognostic (5.55e-2)" "unprognostic (1.39e-1)" 2.1 1.5 1.4 2.4 1.8 4.7 3.8 8.3 3.5 1.6 1.4 2.9 2.0 2.0 1.5 3.1 2.1 1.7 1.0 1.5 1.2 2.4 3.1 1.3 2.5 1.2 1.4 2.5 1.8 1.9 1.3 3.8 1.2 2.7 3.4 3.4 1.7 2.3 1.4 1.9 2.6 2.3 1.2 1.5 1.8 39.3 1.3 6.1 1.4 1.2 3.1 3.1 1.4 3.1 28.6 20.8 40.8 24.1 7.5 10.7 16.9 14.8 8.1 24.1 34.6 29.5 15.2 22.4 13.4 5.8 22.6 21.3 27.7 16.4 31.6 22.9 15.1 29.4 14.0 21.5 4.3 14.8 16.2 4.1 5.3 24.2 5.4 6.4 19.0 37.4 41.9 15.2 20.3 19.3 31.3 4.4 28.8 26.6 5.9 38.4 28.1 20.7 10.9 11.0 13.8 16.8 23.9 16.6 11.1 23.8 24.6 11.0 11.6 21.4 31.7 22.9 23.1 9.5 36.1 47.9 12.1 14.8 13.5 0.2 0.3 0.2 1.5 1.1 1.9 0.4 1.1 1.7 1.1 0.3 1.8 1.8 0.3 3.0 0.4 1.8 2.0 0.5 1.4 1.8 8.3 3.5 1.5 1.2 1.2 1.4 1.2 1.2 1.3 3.1 2.0 0.0 1.5 4.2 2.6 8.3 10.2 6.7 9.1 7.5 4.0 3.7 2.9 2.8 7.5 1.8 10.4 13.9 1.7 1.1 5.9 4.4 421.0 3.4 5.1 4.3 3.5 16.2 8.0 2.2 25.6 5.1 4.1 4.0 2.5 7.8 1.8 3.0 5.0 11.8 7.9 3.1 6.1 1.6 2.8 104.4 4.7 1.8 1.8 2.8 0.7 4.2 3.1 4.5 4.5 2.1 1.7 2.6 7.1 14.5 1.0 7.4 3.5 10.2 6.6 5.8 6.6 47.5 46.6 8.3 8.8 8.9 3.4 8.7 4.5 10.9 SYNJ2BP Arip2 ENSG00000213463 "Synaptojanin 2 binding protein" P57105 14 70366499-70417090 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 140.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA000866 Approved Supported Approved Mitochondria NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 8: Non-specific - Mitochondria" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 44: Endometrium - Transcription" Mitochondria "HPA000866: AB_2276678" "unprognostic (2.68e-1)" "unprognostic (1.76e-1)" "unprognostic (2.67e-1)" "unprognostic (3.31e-1)" "unprognostic (1.28e-1)" "unprognostic (1.04e-1)" "unprognostic (1.65e-1)" "unprognostic (1.60e-2)" "unprognostic (5.70e-2)" "unprognostic (6.14e-2)" "unprognostic (6.35e-3)" "unprognostic (1.44e-2)" "prognostic favorable (1.11e-16)" "unprognostic (2.81e-1)" "unprognostic (1.38e-1)" "unprognostic (5.35e-3)" "unprognostic (1.14e-2)" 10.2 10.1 10.3 7.3 10.1 1.3 9.9 9.3 10.0 8.1 13.3 13.7 19.6 9.0 7.9 8.2 7.2 8.4 14.9 8.4 9.3 21.7 20.3 9.5 6.6 10.0 9.8 7.2 7.4 24.9 6.6 9.3 9.8 12.9 15.1 16.4 9.5 11.9 28.7 5.7 16.0 10.7 10.8 9.1 15.5 3.9 10.6 5.1 11.2 29.3 6.4 8.6 6.1 9.7 14.0 9.1 15.3 10.3 11.7 13.4 10.6 10.8 11.1 7.4 8.3 8.7 12.8 0.0 10.0 12.7 7.5 11.6 15.7 11.6 17.5 1.9 8.0 5.2 13.9 11.4 10.3 0.0 1.7 10.5 9.2 9.4 5.3 13.1 16.6 5.8 3.1 2.7 13.4 10.2 7.2 2.1 11.1 13.9 10.9 9.0 22.4 3.9 16.0 20.7 11.1 19.4 14.6 12.0 8.8 9.9 22.7 3.6 18.5 17.7 12.1 6.9 8.7 3.7 15.0 0.0 15.6 1.8 14.9 0.3 3.0 0.1 2.3 3.1 2.7 2.5 2.8 2.7 3.0 2.0 3.8 3.1 0.3 2.3 2.1 1.9 2.3 1.1 10.3 10.1 9.3 10.0 8.4 9.3 10.0 9.8 9.8 10.8 10.6 9.7 36.6 38.5 46.6 0.0 17.8 6.0 28.7 49.4 9.1 44.9 25.9 15.4 89.4 48.6 43.3 75.4 81.3 38.3 13.1 50.1 140.8 49.0 36.9 56.0 26.5 38.4 19.8 5.7 0.0 39.2 31.5 21.7 21.9 85.7 9.5 33.5 37.1 50.4 24.7 30.3 0.0 41.2 44.7 23.6 9.1 9.8 30.4 16.9 14.2 0.0 28.8 37.1 28.8 0.0 0.0 35.7 43.5 41.3 4.2 25.8 87.3 77.0 31.5 88.0 26.3 37.6 27.8 68.9 12.9 12.5 4.8 10.9 17.4 25.0 62.6 30.3 SYNJ2BP-COX16 ENSG00000258644 "SYNJ2BP-COX16 readthrough" 14 70326064-70417074 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 11.3" "Cell type enhanced" "Detected in some" "Erythroid cells: 4.8;Excitatory neurons: 3.1;Inhibitory neurons: 2.7" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 10.1;U-2 OS: 10.6" "Low region specificity" "Detected in all" "HPA000866, HPA062659" Approved Supported Approved Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA000866: AB_2276678, HPA062659: AB_2684823" "unprognostic (9.44e-2)" "unprognostic (2.42e-1)" "unprognostic (4.33e-2)" "unprognostic (1.68e-2)" "unprognostic (1.06e-1)" "unprognostic (1.34e-1)" "unprognostic (8.70e-2)" "unprognostic (2.02e-1)" "unprognostic (1.96e-2)" "unprognostic (3.00e-1)" "unprognostic (2.21e-2)" "unprognostic (6.41e-2)" "unprognostic (6.73e-4)" "unprognostic (6.68e-2)" "unprognostic (6.93e-2)" "unprognostic (2.55e-1)" "unprognostic (2.12e-2)" 2.7 2.8 0.4 1.4 0.6 0.4 2.2 0.7 2.5 2.6 0.5 2.9 1.1 2.6 0.8 1.8 1.8 0.8 4.3 0.5 0.7 3.6 2.3 2.1 1.7 0.6 0.5 2.8 0.7 1.3 1.7 1.0 0.6 1.9 0.7 0.7 1.2 0.5 3.1 1.3 1.3 1.5 0.5 1.9 2.1 11.3 0.5 2.4 1.7 2.4 1.1 2.5 1.8 0.5 5.9 1.6 3.4 1.2 0.0 0.2 2.3 6.2 0.5 2.7 2.4 0.6 7.4 0.0 4.6 0.0 4.9 4.7 0.0 1.1 2.0 0.7 2.0 0.0 1.0 2.5 2.6 0.0 1.2 0.0 1.4 2.3 0.0 4.2 1.9 4.7 0.0 0.5 1.6 0.4 3.6 1.1 1.6 10.1 1.8 4.7 0.7 2.9 1.4 2.3 2.9 4.7 1.1 2.2 3.5 4.2 2.2 2.9 0.0 2.9 10.6 0.0 3.2 0.3 2.6 0.0 5.3 0.0 4.0 1.6 8.9 0.1 11.1 11.2 11.5 14.4 12.1 11.0 12.0 13.6 11.4 10.8 0.0 15.1 5.7 9.2 12.8 7.9 0.4 0.6 0.7 2.5 0.5 0.7 0.6 0.5 0.6 0.5 0.5 0.5 0.6 0.0 0.5 1.0 1.1 0.0 0.1 0.0 1.2 0.3 0.4 0.1 0.0 0.0 0.6 0.0 0.0 0.3 1.4 0.0 1.9 0.4 1.6 2.0 0.7 1.8 0.0 4.8 3.1 0.8 0.4 1.1 1.1 2.6 0.0 0.3 0.7 0.7 0.2 0.0 2.7 0.0 0.0 0.8 0.0 0.9 0.6 1.0 0.0 0.0 0.1 0.3 2.1 0.5 0.6 0.3 0.1 0.4 2.4 0.0 0.2 0.6 0.0 0.3 0.0 0.2 0.9 1.0 0.2 1.5 0.0 0.3 0.6 0.2 0.4 0.0 TACO1 CCDC44 ENSG00000136463 "Translational activator of cytochrome c oxidase I" Q9BSH4 17 63600882-63608365 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Translation regulation" Activator "Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 69.2" "Cell type enhanced" "Detected in all" "Hepatocytes: 87.9;Proximal enterocytes: 81.2;Proximal tubular cells: 109.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021626, HPA021643, HPA024294" Enhanced Enhanced Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA021626: AB_1846148, HPA021643: AB_1846149, HPA024294: AB_1846150" "unprognostic (1.26e-1)" "unprognostic (2.92e-2)" "unprognostic (4.55e-3)" "unprognostic (9.82e-2)" "unprognostic (1.30e-1)" "unprognostic (9.30e-3)" "unprognostic (2.83e-1)" "unprognostic (8.09e-2)" "unprognostic (2.09e-1)" "unprognostic (7.38e-2)" "prognostic favorable (3.73e-4)" "unprognostic (1.35e-1)" "unprognostic (4.12e-3)" "unprognostic (5.21e-3)" "unprognostic (1.13e-1)" "unprognostic (1.51e-1)" "unprognostic (1.60e-2)" 12.8 18.6 16.6 8.2 17.4 8.3 10.9 18.9 18.4 8.8 17.7 17.8 18.9 11.1 9.7 13.4 9.3 5.5 42.3 16.5 17.5 30.1 69.2 7.7 10.4 17.4 17.4 8.3 12.0 18.2 9.5 8.3 17.3 9.5 16.1 9.4 11.4 9.2 61.5 11.3 16.7 9.7 16.9 11.5 15.1 12.1 17.6 9.9 9.4 55.9 12.2 11.8 9.2 16.7 39.6 61.2 19.4 20.2 16.5 23.5 25.7 28.5 26.8 56.2 44.4 40.5 23.2 32.6 21.2 33.1 38.9 35.8 43.0 41.5 52.6 17.3 58.1 32.0 29.8 72.3 45.5 38.3 21.7 29.0 28.6 48.5 51.1 20.9 29.6 24.2 44.4 24.1 26.6 71.6 44.7 28.7 16.8 42.5 62.9 28.1 47.7 40.8 33.2 27.6 29.5 32.4 19.6 64.0 55.3 25.3 53.3 29.1 26.4 39.9 29.9 27.5 50.7 25.9 27.2 38.7 30.4 26.0 29.6 2.2 9.4 9.0 9.8 8.5 10.7 7.5 13.7 9.7 10.6 9.9 12.4 10.3 1.4 17.8 7.4 7.0 10.2 9.4 16.6 17.4 18.9 18.4 16.5 17.5 17.4 17.4 17.3 16.9 17.6 16.7 9.8 3.2 6.3 2.6 12.0 2.5 8.0 21.1 8.6 8.2 7.8 10.9 54.0 17.2 11.5 14.7 2.1 32.1 8.2 32.9 54.8 29.1 15.3 8.0 11.4 14.2 13.8 17.4 4.0 27.4 28.9 14.1 16.8 6.4 9.5 16.2 8.6 87.9 26.3 6.7 3.9 21.7 12.2 10.7 3.9 46.0 11.8 9.2 10.6 2.8 22.0 15.5 14.4 1.5 3.2 30.0 25.8 11.3 10.7 11.6 81.2 109.7 9.1 13.4 19.7 10.7 14.6 26.8 13.9 18.6 4.3 19.8 10.1 40.7 32.8 7.1 TAOK3 "DPK, JIK, MAP3K18" ENSG00000135090 "TAO kinase 3" Q9H2K8 12 118149801-118372907 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 400.6;Rod photoreceptor cells: 323.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 123.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017160 Approved Uncertain Mitochondria NA NA 520000 "Cluster 18: Basophils - Vesicular transport" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 46: Photoreceptor cells - Phototransduction" Mitochondria "HPA017160: AB_1851994" "unprognostic (3.21e-1)" "unprognostic (1.31e-1)" "unprognostic (1.65e-1)" "unprognostic (3.74e-2)" "unprognostic (5.18e-2)" "unprognostic (2.09e-1)" "unprognostic (4.80e-1)" "unprognostic (5.86e-2)" "unprognostic (1.00e-1)" "unprognostic (7.38e-2)" "unprognostic (2.76e-2)" "unprognostic (8.23e-2)" "unprognostic (1.08e-2)" "unprognostic (2.08e-2)" "unprognostic (4.14e-3)" "unprognostic (2.56e-1)" "unprognostic (1.44e-1)" 15.4 18.2 33.9 24.9 35.7 41.9 17.1 36.8 38.5 12.7 27.9 23.8 27.1 16.8 12.7 18.2 10.5 19.5 18.5 33.0 38.1 16.2 18.4 23.2 33.8 34.2 35.3 19.3 11.7 15.5 18.7 14.3 33.5 29.0 24.6 48.3 15.2 16.0 21.8 20.3 28.8 17.7 33.6 26.0 25.2 10.7 41.2 31.6 21.1 13.0 33.0 20.6 13.3 42.6 25.7 17.2 12.7 11.1 30.6 37.0 14.5 26.2 29.8 14.9 19.3 8.9 38.5 77.4 8.4 34.9 21.5 22.5 11.2 23.5 23.3 28.3 9.2 91.7 9.0 11.7 35.6 95.2 123.5 25.3 27.7 46.9 68.4 31.3 48.3 45.5 54.3 9.0 27.8 18.2 50.0 62.0 4.7 11.7 9.2 29.1 17.2 8.3 14.1 43.8 2.3 12.5 24.1 10.9 33.6 5.5 22.0 70.0 75.9 25.5 4.5 24.2 22.6 8.7 8.9 60.6 35.8 64.1 35.2 122.3 39.4 91.5 60.9 53.8 58.1 47.9 46.0 53.4 52.4 44.9 40.3 52.9 86.2 86.9 95.4 48.8 46.6 46.0 33.9 35.7 36.8 38.5 33.0 38.1 34.2 35.3 33.5 33.6 41.2 42.6 43.2 35.3 98.9 203.4 110.7 35.2 46.7 30.4 38.1 69.9 52.3 39.6 57.6 52.9 36.7 46.0 212.7 36.1 138.5 116.3 70.5 40.3 18.6 17.5 30.6 36.2 25.1 65.2 117.0 59.1 93.5 37.8 75.4 39.2 167.6 31.6 29.6 57.7 78.5 40.4 156.2 80.7 22.4 104.3 103.0 10.3 38.8 160.5 35.6 133.0 156.9 48.4 217.3 400.6 202.2 91.0 111.7 47.8 84.9 44.4 105.2 37.4 20.7 323.8 46.0 29.9 55.2 101.4 53.3 48.3 31.4 43.8 103.5 66.4 69.3 53.7 TBC1D32 "bA57L9.1, BROMI, C6orf170, C6orf171, dJ310J6.1, FLJ30899, FLJ34235" ENSG00000146350 "TBC1 domain family member 32" Q96NH3 6 121079494-121334745 "Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 7.4" "Cell type enhanced" "Detected in many" "Astrocytes: 68.2;Excitatory neurons: 124.1;Inhibitory neurons: 87.4;Oligodendrocyte precursor cells: 105.6;Oligodendrocytes: 102.6;Rod photoreceptor cells: 110.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 22.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013413 Uncertain Approved Mitochondria NA NA "Cluster 6: Non-specific - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 44: HDLM-2 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" Mitochondria "HPA013413: AB_10602702" "unprognostic (3.31e-2)" "unprognostic (1.28e-1)" "unprognostic (9.12e-3)" "unprognostic (4.82e-2)" "unprognostic (2.44e-2)" "unprognostic (1.98e-2)" "unprognostic (3.60e-4)" "unprognostic (7.28e-2)" "unprognostic (1.02e-1)" "unprognostic (1.83e-1)" "unprognostic (8.14e-2)" "unprognostic (2.01e-2)" "unprognostic (3.73e-2)" "unprognostic (1.57e-2)" "unprognostic (7.62e-2)" "unprognostic (2.17e-1)" "unprognostic (2.06e-1)" 1.2 2.4 0.8 0.9 1.5 0.8 1.7 0.6 1.4 1.8 0.9 1.1 1.8 1.7 0.8 1.0 1.6 1.9 0.7 0.8 1.6 1.4 0.4 0.9 1.0 1.1 1.4 1.8 1.3 2.3 1.5 2.9 1.2 1.6 0.7 7.4 0.8 0.9 0.2 1.2 1.4 0.8 0.6 1.0 1.3 3.6 1.8 1.6 2.4 0.5 1.1 1.0 0.9 2.5 1.7 2.0 3.4 4.4 2.8 4.5 1.8 1.9 2.9 3.2 4.6 0.1 1.3 3.4 3.2 2.0 4.7 1.5 1.6 1.6 4.0 22.7 2.2 3.9 0.7 0.7 1.2 2.1 1.5 1.7 1.2 2.8 2.1 3.8 0.7 3.9 2.2 0.0 2.5 1.0 2.3 1.3 1.9 1.1 0.7 2.1 1.6 0.3 1.6 0.8 6.5 3.5 2.2 1.4 1.0 1.8 2.1 1.6 0.4 2.1 2.1 0.6 2.2 1.6 0.0 1.3 3.0 1.1 3.3 6.1 0.9 1.3 1.8 0.5 1.3 2.5 1.4 1.3 0.7 4.5 2.6 2.0 0.8 2.6 0.9 8.2 1.6 0.3 0.8 1.5 0.6 1.4 0.8 1.6 1.1 1.4 1.2 0.6 1.8 2.5 3.9 3.2 8.4 68.2 6.4 6.1 3.7 3.1 9.6 26.2 6.1 5.0 3.1 4.3 10.1 7.3 43.8 4.4 8.7 3.4 0.0 2.4 9.8 8.8 9.5 3.5 5.4 1.7 124.1 2.2 1.7 6.2 10.2 4.7 3.8 26.7 2.9 1.1 1.4 13.5 87.4 6.0 4.1 1.6 2.9 3.5 2.5 2.8 1.8 36.5 1.5 6.7 3.1 105.6 102.6 1.0 3.9 1.9 1.8 2.3 8.0 1.5 20.3 110.4 0.0 6.6 5.3 21.5 7.9 3.4 5.1 2.3 4.9 4.8 4.8 2.3 TBRG4 "Cpr2, FASTKD4, H_TD2522F11.8, KIAA0948" ENSG00000136270 "Transforming growth factor beta regulator 4" Q969Z0 7 45100100-45112047 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020582, HPA050430" Approved Enhanced Mitochondria NA NA 23000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA020582: AB_1857804, HPA050430: AB_2681125" "unprognostic (2.22e-1)" "unprognostic (4.75e-2)" "unprognostic (1.19e-1)" "unprognostic (3.46e-3)" "unprognostic (1.41e-2)" "unprognostic (9.29e-3)" "prognostic unfavorable (1.40e-4)" "unprognostic (3.15e-2)" "unprognostic (1.86e-1)" "unprognostic (2.83e-1)" "unprognostic (4.53e-1)" "unprognostic (1.25e-2)" "unprognostic (3.66e-3)" "unprognostic (3.91e-2)" "unprognostic (3.84e-2)" "unprognostic (3.30e-1)" "unprognostic (1.52e-1)" 24.5 29.5 19.3 23.0 21.8 23.0 24.0 22.8 21.4 22.9 23.5 36.1 29.4 23.1 7.9 35.8 21.2 11.9 56.5 19.7 21.6 29.6 43.3 19.0 25.5 22.4 21.1 24.0 21.3 21.9 17.4 19.5 23.0 24.5 18.7 6.6 24.1 15.6 83.0 32.4 28.6 15.6 21.4 28.5 26.2 34.4 22.0 21.9 18.9 66.2 17.9 29.3 25.5 23.2 49.4 113.1 35.7 77.3 31.5 28.9 70.2 39.2 35.9 74.6 61.5 123.8 67.5 93.8 58.7 39.9 103.3 125.6 82.6 89.3 37.6 49.0 77.8 64.5 73.6 84.4 51.6 74.5 63.4 39.7 81.7 71.2 50.7 26.7 46.6 79.3 181.1 46.0 46.2 84.5 75.9 168.0 111.0 110.6 88.6 65.9 45.3 136.2 44.1 50.4 69.9 65.6 40.4 218.8 77.6 45.6 97.7 120.4 36.4 54.6 65.7 33.9 64.8 81.0 87.6 137.5 50.1 104.9 125.7 17.3 23.8 20.6 31.1 44.3 29.5 27.9 25.6 30.0 35.9 20.9 34.5 33.3 1.9 18.1 39.5 13.6 27.2 33.0 19.3 21.8 22.8 21.4 19.7 21.6 22.4 21.1 23.0 21.4 22.0 23.2 13.3 3.2 16.3 9.4 21.0 35.1 33.2 39.8 15.4 15.1 17.0 15.0 28.0 15.7 24.1 20.2 0.0 61.5 18.4 32.9 43.0 31.1 24.6 12.5 13.8 14.2 22.2 14.3 6.5 18.3 72.5 17.9 24.5 16.9 14.0 25.4 10.4 31.8 34.5 11.8 7.1 32.5 36.7 12.3 17.8 19.6 16.4 18.0 17.8 3.7 34.6 14.7 14.4 4.5 8.4 29.5 28.0 11.7 17.9 33.8 33.5 47.4 11.2 14.2 13.1 17.1 25.5 72.4 33.0 17.0 29.3 47.9 19.2 44.7 53.3 30.2 TCIRG1 "a3, Atp6i, ATP6N1C, ATP6V0A3, OC-116, OC116, TIRC7" ENSG00000110719 "T cell immune regulator 1, ATPase H+ transporting V0 subunit a3" Q13488 11 68039025-68050895 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" "Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 289.2" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 135.5;Kupffer cells: 115.2;Macrophages: 132.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 131.9;RPMI-8226: 138.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038742 Approved Approved Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Mitochondria "HPA038742: AB_10795138" "unprognostic (5.35e-2)" "unprognostic (5.01e-2)" "unprognostic (1.81e-2)" "unprognostic (1.50e-2)" "unprognostic (6.98e-3)" "unprognostic (1.25e-1)" "unprognostic (5.07e-2)" "unprognostic (6.43e-2)" "unprognostic (7.03e-2)" "unprognostic (2.47e-2)" "unprognostic (1.36e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.50e-11)" "unprognostic (2.48e-3)" "unprognostic (7.88e-3)" "unprognostic (2.50e-1)" "prognostic favorable (9.45e-6)" 56.8 112.5 7.1 46.1 7.1 97.7 47.2 9.2 14.5 85.1 11.4 66.6 44.2 58.0 18.6 45.3 61.4 11.7 27.9 6.6 7.2 35.5 61.7 113.9 30.9 10.9 9.3 49.1 289.2 4.4 20.3 14.1 12.0 72.2 8.0 0.3 57.9 16.1 10.5 25.9 87.0 12.1 9.1 194.8 59.2 6.7 18.1 12.1 52.5 3.9 13.4 56.1 60.7 10.8 31.8 57.2 0.8 0.2 25.1 19.7 39.0 61.5 29.4 17.2 16.3 1.3 92.0 2.7 32.9 21.9 26.2 39.0 3.7 23.5 3.6 82.1 1.9 22.0 80.6 18.9 23.4 16.3 131.9 22.8 13.5 21.2 1.4 0.0 11.8 1.2 11.6 8.4 5.7 10.7 0.8 97.8 3.5 44.6 14.4 26.8 0.9 138.6 16.2 17.6 3.0 0.7 26.0 33.4 16.8 6.1 36.3 41.1 42.3 33.2 25.9 93.3 11.4 1.3 1.2 4.8 74.0 26.7 16.2 21.7 65.5 72.8 15.7 109.0 12.7 11.3 11.7 16.9 49.0 7.5 6.6 7.2 150.0 32.1 144.3 33.8 12.1 47.8 7.1 7.1 9.2 14.5 6.6 7.2 10.9 9.3 12.0 9.1 18.1 10.8 40.6 28.9 59.8 0.3 37.1 6.2 13.2 36.2 7.4 0.7 14.9 8.9 1.6 18.6 57.1 7.3 0.0 21.7 60.6 74.2 0.0 30.4 0.4 13.3 16.7 22.1 23.9 15.2 0.3 67.0 54.1 24.9 135.5 21.5 50.0 29.5 21.0 17.8 105.1 0.0 0.6 32.4 18.3 115.2 22.8 0.6 5.9 132.3 5.4 8.4 74.9 0.7 45.3 0.5 0.1 51.8 85.4 13.2 59.1 10.6 45.5 2.0 47.9 1.0 39.5 7.7 26.0 0.1 2.9 10.4 5.3 26.5 46.5 9.0 36.2 19.0 TEFM "C17orf42, FLJ22729" ENSG00000172171 "Transcription elongation factor, mitochondrial" Q96QE5 17 30897336-30906238 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023788, HPA053044" Approved Enhanced Mitochondria No No "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Mitochondria "HPA023788: AB_1848818, HPA053044: AB_2682023" "unprognostic (1.22e-1)" "unprognostic (1.18e-2)" "unprognostic (1.11e-3)" "unprognostic (3.31e-2)" "unprognostic (7.89e-2)" "unprognostic (3.75e-1)" "prognostic unfavorable (9.20e-4)" "unprognostic (1.25e-1)" "prognostic unfavorable (8.64e-4)" "unprognostic (2.11e-1)" "unprognostic (6.18e-3)" "unprognostic (9.39e-2)" "unprognostic (4.79e-2)" "unprognostic (7.90e-2)" "unprognostic (1.92e-1)" "unprognostic (2.23e-1)" "unprognostic (8.37e-3)" 4.9 6.0 4.4 5.9 4.6 2.2 6.7 5.7 6.0 4.0 5.5 5.7 5.6 4.9 4.1 5.2 4.8 4.1 8.9 4.6 4.4 9.6 8.8 4.0 7.3 4.5 4.4 4.8 3.3 6.6 3.2 6.8 4.6 5.0 6.6 6.9 5.4 4.8 6.8 5.3 4.6 5.1 4.3 5.7 5.1 4.2 4.6 5.4 5.4 11.7 6.7 5.4 2.9 5.1 12.8 19.2 10.7 14.9 12.7 12.4 10.1 13.1 9.5 23.7 21.4 15.6 7.2 17.4 12.7 8.1 15.5 21.6 18.6 9.1 22.4 5.5 23.9 8.8 15.1 15.5 8.5 18.7 11.2 7.9 11.7 13.4 6.9 7.2 11.9 12.4 19.1 14.3 13.9 11.7 16.0 24.3 8.9 19.6 12.1 10.5 22.9 17.6 19.2 14.4 16.3 7.5 9.8 11.7 15.4 10.9 23.7 14.1 7.8 10.9 14.7 11.2 13.8 7.9 14.0 16.2 7.3 13.8 13.2 2.6 7.7 6.5 6.4 12.2 8.8 9.8 8.2 6.5 8.1 6.3 9.9 9.2 2.3 8.6 9.9 7.0 10.0 7.1 4.4 4.6 5.7 6.0 4.6 4.4 4.5 4.4 4.6 4.3 4.6 5.1 10.1 16.0 10.6 13.7 11.3 4.1 8.0 22.6 9.1 17.8 6.8 6.9 5.8 11.5 13.6 9.2 8.4 26.0 11.5 5.4 25.4 13.4 10.4 12.6 15.3 9.6 5.4 6.9 27.1 8.5 17.3 10.2 5.1 7.8 5.1 17.2 10.4 10.1 20.4 16.8 27.3 7.4 22.4 7.8 3.0 6.3 8.1 9.6 7.2 21.5 14.0 15.0 16.5 27.2 32.2 12.5 5.6 7.5 7.1 5.2 9.4 17.7 17.8 19.4 19.7 11.0 11.6 27.7 17.8 8.7 4.3 17.8 10.0 18.9 7.9 4.7 TFAM "TCF6, TCF6L2" ENSG00000108064 "Transcription factor A, mitochondrial" Q00059 10 58385345-58399220 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 7 "Early spermatids: 631.4;Late spermatids: 933.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040648, HPA063684" Supported Enhanced Mitochondria "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 34: Spermatids - Unknown function" Mitochondria "HPA040648: AB_10795635, HPA063684: AB_2685089" "unprognostic (5.30e-2)" "unprognostic (1.14e-1)" "unprognostic (6.34e-3)" "prognostic unfavorable (8.73e-4)" "unprognostic (1.10e-2)" "unprognostic (3.40e-2)" "unprognostic (1.54e-2)" "unprognostic (3.23e-2)" "unprognostic (1.24e-2)" "prognostic favorable (2.74e-4)" "unprognostic (1.99e-2)" "unprognostic (5.39e-2)" "prognostic favorable (2.22e-5)" "unprognostic (1.31e-1)" "unprognostic (2.24e-1)" "unprognostic (1.79e-1)" "unprognostic (6.76e-2)" 16.5 20.1 5.7 21.6 6.1 38.1 17.3 10.8 8.4 11.4 6.8 20.0 21.0 13.7 9.5 14.7 12.6 10.7 18.5 5.5 7.3 21.5 22.6 10.9 27.7 5.8 6.1 17.8 13.9 16.2 6.3 20.4 6.5 14.5 17.3 9.8 17.3 11.4 17.7 9.0 17.8 11.6 7.0 17.3 16.1 33.0 6.4 24.9 19.6 16.1 23.0 16.7 7.5 8.8 85.7 47.7 52.8 54.7 15.3 19.4 59.8 37.9 37.3 46.8 51.1 170.0 88.6 170.1 53.9 17.6 34.8 65.2 97.6 53.5 73.4 73.4 85.7 64.1 33.4 64.5 23.3 164.7 49.4 19.2 24.4 57.0 51.6 22.2 41.1 49.9 153.4 74.8 33.2 46.4 130.2 65.1 100.0 39.2 49.9 102.9 113.0 76.0 28.3 57.0 69.8 48.1 75.1 103.7 97.0 42.9 112.8 47.9 32.0 34.4 109.5 39.5 102.5 75.6 125.8 214.2 44.1 125.1 26.4 1.0 9.5 4.0 8.3 9.5 10.8 12.8 10.0 8.8 12.1 12.5 12.4 10.1 7.1 15.0 8.3 14.7 9.0 6.9 5.7 6.1 10.8 8.4 5.5 7.3 5.8 6.1 6.5 7.0 6.4 8.8 46.4 54.5 27.9 6.2 52.5 50.1 44.0 52.4 59.2 25.1 48.6 62.9 35.0 38.6 51.0 20.2 16.7 98.1 56.8 17.1 88.0 41.0 631.4 36.8 44.5 39.5 15.5 46.7 10.1 44.7 77.4 38.8 25.0 41.2 29.7 34.1 26.0 64.1 44.0 38.7 11.5 37.5 18.3 21.9 19.3 933.1 41.3 32.3 23.2 2.8 36.3 38.2 48.4 10.6 11.7 35.2 23.0 30.9 35.8 47.3 14.1 72.0 31.4 21.4 26.3 74.8 40.5 55.3 63.9 48.6 54.7 52.5 38.3 69.1 48.1 31.8 TFB2M "FLJ22661, FLJ23182, Hkp1" ENSG00000162851 "Transcription factor B2, mitochondrial" Q9H5Q4 1 246540561-246566261 "Metabolic proteins, Predicted intracellular proteins" "rRNA processing, Transcription, Transcription regulation" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028482, HPA028554, HPA030265" Approved Enhanced Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA028482: AB_2672633, HPA028554: AB_2732441, HPA030265: AB_10696209" "unprognostic (4.38e-2)" "unprognostic (2.45e-2)" "unprognostic (3.79e-3)" "unprognostic (5.63e-2)" "unprognostic (1.10e-1)" "unprognostic (8.13e-2)" "unprognostic (8.76e-2)" "unprognostic (1.41e-1)" "unprognostic (2.51e-2)" "unprognostic (1.68e-2)" "unprognostic (2.46e-1)" "unprognostic (6.81e-2)" "unprognostic (5.26e-2)" "unprognostic (2.27e-1)" "unprognostic (9.44e-2)" "unprognostic (6.41e-2)" "unprognostic (3.53e-2)" 11.6 23.5 3.6 9.4 3.7 24.2 12.1 6.2 5.0 8.5 6.3 12.6 11.4 7.2 9.5 10.9 8.6 7.1 14.0 3.4 3.9 21.2 37.8 6.3 13.3 3.4 3.5 6.9 15.6 10.8 6.3 9.1 3.5 8.8 12.9 5.0 11.3 7.5 22.7 9.3 9.1 8.0 3.8 7.0 10.1 8.7 3.9 9.3 13.6 24.3 13.2 13.3 6.1 4.1 33.9 31.9 12.1 21.5 14.8 21.1 42.2 24.2 24.8 26.9 24.6 39.0 31.6 59.8 36.9 24.7 17.4 28.5 29.3 25.7 36.8 23.4 11.3 30.3 18.1 34.5 24.2 54.1 26.3 21.0 30.2 23.1 25.8 14.8 21.2 20.9 89.2 19.8 23.4 15.7 27.5 24.1 53.8 58.6 32.1 27.2 23.9 72.9 24.5 36.7 26.7 53.8 23.4 41.9 82.2 13.3 30.6 51.3 15.6 18.7 22.7 26.6 63.8 57.1 102.9 47.6 23.0 52.6 23.9 0.3 5.4 1.5 9.1 5.7 11.5 11.9 8.0 9.7 12.9 12.0 10.3 8.9 1.2 14.8 9.8 11.1 12.3 5.3 3.6 3.7 6.2 5.0 3.4 3.9 3.4 3.5 3.5 3.8 3.9 4.1 11.9 6.4 9.4 4.2 17.2 53.3 13.7 27.9 31.9 3.2 12.4 11.9 16.5 14.3 18.4 16.5 10.4 24.4 13.1 7.6 29.4 13.8 1.5 17.6 12.9 13.2 11.4 8.6 8.1 15.5 28.1 10.2 18.8 22.4 14.0 7.5 5.7 33.9 11.9 0.0 7.2 14.3 6.1 9.3 7.7 3.4 6.5 7.3 5.4 1.9 6.9 6.6 7.2 6.0 5.5 11.0 10.3 4.5 12.7 17.2 7.8 39.2 15.4 3.4 13.1 14.4 12.2 13.2 21.6 21.3 44.9 21.1 10.9 17.7 19.8 10.4 THAP9 FLJ34093 ENSG00000168152 "THAP domain containing 9" Q9H5L6 4 82900684-82919969 "Predicted intracellular proteins, Transcription factors" "DNA integration, DNA recombination" "DNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 40.5;Late spermatids: 52.9;Oligodendrocytes: 20.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA037420, HPA037421" Uncertain Approved Mitochondria No No "Cluster 7: Monocytes - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" Mitochondria "HPA037420: AB_2675467, HPA037421: AB_10673631" "unprognostic (7.54e-3)" "unprognostic (8.52e-2)" "unprognostic (4.14e-2)" "unprognostic (1.51e-2)" "unprognostic (2.06e-1)" "unprognostic (1.18e-2)" "unprognostic (2.26e-1)" "unprognostic (4.51e-2)" "unprognostic (1.17e-1)" "unprognostic (2.30e-2)" "unprognostic (2.30e-2)" "unprognostic (2.65e-2)" "prognostic favorable (3.50e-5)" "unprognostic (1.39e-1)" "unprognostic (1.62e-1)" "unprognostic (4.64e-3)" "unprognostic (8.74e-4)" 1.3 1.6 3.0 1.0 3.6 2.0 3.2 3.3 4.5 2.0 2.6 1.5 1.5 2.5 3.6 1.3 1.7 1.3 2.7 3.1 3.3 3.0 3.2 1.6 1.8 3.4 3.2 3.2 2.5 3.2 2.7 2.1 3.6 2.4 1.6 4.3 2.0 1.9 5.2 1.7 1.5 1.4 3.2 1.4 1.4 6.7 3.1 2.5 4.1 6.8 1.7 1.5 1.6 5.8 1.1 1.5 5.7 3.2 1.7 2.0 4.0 1.1 1.8 1.1 1.0 2.3 2.0 6.3 2.0 1.5 2.1 1.4 4.6 1.8 1.3 2.4 1.7 2.7 2.2 2.9 2.0 2.5 2.1 2.1 2.9 0.5 2.8 1.7 1.7 5.1 2.4 4.2 1.4 1.5 6.1 3.0 4.6 2.2 0.8 5.5 2.4 3.7 2.0 1.3 4.8 3.3 2.2 3.0 4.1 4.7 1.8 2.2 1.1 1.4 1.6 1.1 0.8 2.7 1.3 6.0 1.7 1.5 2.2 0.0 0.9 0.1 0.5 1.4 0.7 1.3 0.4 0.5 1.0 1.1 1.2 1.0 0.0 0.6 1.0 0.6 0.2 0.5 3.0 3.6 3.3 4.5 3.1 3.3 3.4 3.2 3.6 3.2 3.1 5.8 3.2 3.2 3.6 8.5 2.8 0.8 2.8 2.3 2.2 2.8 2.4 2.3 5.0 0.0 2.2 1.8 6.2 3.2 3.6 1.3 0.0 1.6 40.5 4.0 2.8 2.0 3.0 2.5 4.6 2.5 2.0 2.3 5.6 4.2 1.3 4.2 1.4 1.3 1.3 0.0 4.7 1.7 2.0 0.8 1.3 52.9 1.8 2.6 0.0 3.7 1.3 4.0 2.1 7.5 20.8 0.9 0.7 0.0 2.3 1.8 1.1 2.5 1.9 4.7 6.6 4.6 2.8 6.1 5.2 2.6 1.7 3.3 2.0 1.4 1.5 2.0 TIMM10 "TIM10, TIM10A, TIMM10A" ENSG00000134809 "Translocase of inner mitochondrial membrane 10" P62072 11 57528464-57530803 "Predicted intracellular proteins" "Protein transport, Translocation, Transport" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 284.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039946 Supported Enhanced Mitochondria NA NA 16000 "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA039946: AB_10673023" "unprognostic (9.34e-3)" "unprognostic (1.16e-2)" "unprognostic (2.21e-1)" "unprognostic (2.01e-1)" "unprognostic (4.42e-2)" "unprognostic (1.25e-2)" "unprognostic (2.74e-1)" "unprognostic (1.39e-1)" "unprognostic (2.07e-1)" "unprognostic (3.40e-3)" "unprognostic (7.62e-2)" "unprognostic (1.18e-1)" "unprognostic (5.96e-2)" "unprognostic (9.87e-2)" "unprognostic (1.96e-1)" "unprognostic (1.62e-2)" "unprognostic (2.15e-2)" 40.5 41.6 55.1 28.5 56.9 34.8 42.5 56.3 68.3 24.8 53.2 35.5 27.0 27.2 43.8 44.1 25.1 20.3 60.9 56.7 57.4 50.7 77.6 27.9 45.8 55.8 55.6 25.5 33.6 45.1 29.2 21.7 56.1 31.0 35.9 15.1 28.0 30.2 77.8 33.7 27.8 27.5 58.5 37.9 35.3 35.6 56.1 38.5 29.7 67.7 50.1 33.7 27.2 58.0 115.6 171.9 79.1 76.0 67.6 57.2 99.7 96.6 77.0 151.1 85.9 127.6 97.9 218.1 108.0 86.5 131.4 86.3 114.0 112.6 136.4 74.8 84.9 139.4 67.0 167.5 71.3 183.3 148.0 54.2 89.6 146.1 101.4 40.0 95.2 142.8 157.1 96.7 112.7 241.1 99.4 243.5 83.4 99.9 184.4 163.5 167.0 190.3 77.6 78.2 64.0 82.2 101.5 198.6 128.6 77.7 150.1 69.3 60.2 86.0 160.5 150.6 188.1 133.2 192.6 176.1 79.2 91.3 146.2 30.9 88.3 20.9 71.5 84.2 81.6 187.6 86.4 79.0 146.4 179.0 118.0 103.6 4.9 67.3 81.3 146.6 84.0 145.1 55.1 56.9 56.3 68.3 56.7 57.4 55.8 55.6 56.1 58.5 56.1 58.0 53.2 12.8 11.0 3.9 66.4 122.9 42.9 94.5 54.1 16.9 103.1 142.2 124.1 78.6 45.6 44.1 4.2 68.0 52.5 78.2 211.3 84.1 134.7 36.7 28.1 55.8 27.0 56.8 3.2 125.6 88.2 42.0 24.5 39.1 52.6 30.1 40.4 212.3 125.9 8.4 3.9 61.0 48.8 71.7 100.3 284.7 46.3 52.9 81.8 3.7 103.2 55.0 56.7 3.0 5.6 85.3 63.5 51.1 51.5 102.4 120.3 227.3 23.2 15.5 13.1 50.5 71.3 85.9 52.8 78.1 129.7 39.5 42.2 37.7 92.6 52.4 TIMM23 TIM23 ENSG00000265354 "Translocase of inner mitochondrial membrane 23" O14925 10 45972489-46003742 "Predicted membrane proteins" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 148.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA031408 Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "HPA031408: AB_10600828" "unprognostic (4.09e-2)" "unprognostic (1.31e-1)" "unprognostic (9.01e-2)" "unprognostic (1.49e-1)" "unprognostic (1.27e-1)" "unprognostic (1.15e-2)" "prognostic unfavorable (2.77e-5)" "unprognostic (1.74e-1)" "unprognostic (3.90e-2)" "prognostic favorable (6.79e-4)" "unprognostic (4.41e-2)" "unprognostic (7.30e-2)" "unprognostic (3.24e-1)" "unprognostic (7.78e-2)" "unprognostic (5.54e-2)" "unprognostic (7.20e-2)" "unprognostic (2.21e-1)" 39.0 50.1 47.1 35.5 48.7 66.4 38.3 50.3 62.9 28.2 55.6 40.1 56.5 26.8 61.9 43.1 28.0 31.7 84.9 49.1 51.6 59.5 74.2 26.6 36.4 50.7 51.5 20.6 32.2 50.5 35.0 35.2 52.3 34.6 39.9 42.9 32.5 36.9 128.5 35.7 37.7 37.6 49.9 25.6 32.8 80.6 50.5 40.0 43.3 134.5 45.4 53.0 27.1 49.0 162.6 167.5 108.7 110.3 88.5 82.4 106.1 130.6 156.1 155.6 164.0 212.8 125.4 144.1 105.7 138.6 111.3 136.1 168.0 139.9 153.3 108.0 165.6 92.1 120.8 231.7 142.2 173.1 98.7 99.4 122.3 133.4 188.0 64.7 146.1 123.0 166.0 78.8 138.7 162.7 155.5 239.0 131.7 119.0 51.8 118.6 105.0 105.5 177.6 111.8 127.3 117.0 72.8 159.4 132.8 83.8 168.7 102.1 108.1 74.8 130.6 96.8 188.9 83.6 148.9 203.2 139.3 246.7 63.9 54.8 98.1 54.3 73.1 131.1 75.7 82.1 70.0 79.1 111.2 79.8 62.5 69.5 22.8 79.1 118.6 92.2 85.8 129.5 47.1 48.7 50.3 62.9 49.1 51.6 50.7 51.5 52.3 49.9 50.5 49.0 13.3 9.6 22.2 10.7 19.4 21.9 18.1 32.7 15.9 14.3 16.0 11.9 97.5 30.0 24.4 12.9 8.4 42.1 17.0 16.1 45.0 40.4 101.5 26.6 20.8 18.3 10.2 43.3 19.1 30.1 47.7 24.8 20.9 23.8 27.8 14.2 13.2 27.3 34.5 0.0 18.6 16.5 36.7 16.0 15.8 35.0 17.7 18.9 23.2 12.2 29.3 23.0 20.6 14.6 19.6 36.7 14.7 11.7 36.0 20.3 22.3 61.0 26.9 10.4 6.6 13.1 26.0 148.7 48.4 38.7 21.6 35.6 16.6 17.0 25.6 22.4 TIMM44 TIM44 ENSG00000104980 "Translocase of inner mitochondrial membrane 44" O43615 19 7926718-7943667 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043052, HPA073108" Supported Enhanced Mitochondria NA NA 9100 "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA043052: AB_10795713, HPA073108: " "unprognostic (1.75e-1)" "unprognostic (7.44e-3)" "unprognostic (2.68e-2)" "unprognostic (1.03e-1)" "unprognostic (1.24e-1)" "unprognostic (1.45e-2)" "unprognostic (5.81e-3)" "unprognostic (8.78e-2)" "unprognostic (2.42e-1)" "unprognostic (8.81e-2)" "unprognostic (2.07e-3)" "unprognostic (8.93e-2)" "unprognostic (1.80e-2)" "unprognostic (6.01e-2)" "unprognostic (6.43e-2)" "unprognostic (2.07e-2)" "unprognostic (4.18e-2)" 15.2 25.1 16.1 11.2 15.2 8.4 13.0 15.9 22.8 20.2 16.3 27.6 16.9 18.3 7.0 20.9 13.9 6.8 52.3 15.8 15.4 20.0 34.6 10.7 11.1 15.4 15.2 16.2 17.6 13.5 14.4 8.3 15.6 17.5 8.2 4.2 14.0 11.6 62.1 15.7 14.3 10.2 16.6 19.4 20.8 11.0 17.6 7.7 13.8 49.2 8.1 20.1 15.3 16.2 64.5 37.2 24.4 52.0 28.6 28.6 33.3 34.9 26.6 43.8 39.6 82.5 18.1 98.5 45.5 27.5 37.3 46.6 75.7 38.4 21.7 45.5 98.7 53.6 31.4 70.1 72.4 66.3 21.9 31.6 60.1 37.0 53.5 19.4 30.4 53.3 97.2 55.7 20.7 58.5 59.2 53.7 61.3 61.8 116.8 60.4 35.6 68.8 24.9 42.0 46.2 28.3 39.0 50.5 112.8 19.3 29.7 64.4 19.6 30.1 40.2 69.7 72.5 70.4 84.8 99.5 24.2 92.7 48.6 14.3 12.9 4.1 11.3 14.1 10.4 8.6 11.0 10.9 16.4 7.9 9.9 10.6 1.1 10.3 8.7 12.5 9.8 9.5 16.1 15.2 15.9 22.8 15.8 15.4 15.4 15.2 15.6 16.6 17.6 16.2 20.0 35.3 16.4 13.7 31.8 27.9 33.7 41.9 14.2 53.0 43.8 37.6 36.1 32.9 21.5 29.5 41.7 38.5 25.6 48.4 66.5 47.8 11.7 24.8 42.1 22.2 40.1 28.2 13.5 42.9 43.2 25.4 19.4 31.6 33.0 26.4 20.3 62.2 34.9 52.2 13.9 45.5 26.4 21.7 11.1 13.7 36.7 17.2 21.4 1.9 22.9 23.5 44.3 11.1 10.9 42.1 29.0 29.3 25.8 31.8 45.9 75.1 12.4 63.6 32.9 25.0 33.7 38.7 33.9 18.7 19.9 32.6 20.2 29.5 64.6 30.9 TIMM8A "DDP, DFN1, MTS" ENSG00000126953 "Translocase of inner mitochondrial membrane 8A" O60220 X 101345661-101348742 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Translocation, Transport" Chaperone "Deafness, Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 102.2;Hepatocytes: 68.3;Suprabasal keratinocytes: 88.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 217.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003628 Supported Supported Mitochondria NA NA 59000 "Cluster 30: Non-specific - Translation" "Cluster 8: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 28: Keratinocytes - Keratinization" Mitochondria "HPA003628: AB_1080284" "prognostic unfavorable (7.89e-5)" "unprognostic (1.36e-1)" "unprognostic (2.80e-1)" "prognostic unfavorable (8.87e-5)" "unprognostic (2.06e-1)" "unprognostic (9.28e-3)" "unprognostic (5.14e-3)" "unprognostic (8.32e-2)" "unprognostic (1.90e-2)" "unprognostic (1.86e-3)" "unprognostic (6.41e-2)" "unprognostic (8.57e-3)" "prognostic favorable (1.69e-4)" "unprognostic (1.14e-2)" "unprognostic (7.75e-2)" "unprognostic (1.70e-1)" "unprognostic (3.86e-2)" 5.1 5.6 4.3 6.5 4.4 6.9 7.6 5.1 5.2 4.4 4.8 7.2 6.6 4.2 4.7 7.0 5.6 3.6 10.9 4.5 5.3 9.2 25.3 3.1 8.2 4.5 5.5 5.9 5.2 6.7 1.9 6.3 4.5 6.5 7.5 5.0 6.0 3.7 10.0 6.5 6.3 4.8 5.0 4.5 4.2 3.2 5.2 6.8 6.5 14.0 8.7 6.5 3.1 4.3 31.5 30.0 17.1 33.8 13.3 15.0 20.3 23.5 11.4 20.0 40.6 26.4 21.3 38.0 29.7 17.8 36.5 27.7 46.2 24.5 33.3 17.7 29.9 62.8 44.7 46.5 12.7 39.9 217.8 15.0 21.5 30.0 18.8 9.6 19.7 15.9 51.0 40.8 26.8 50.7 18.3 39.1 55.3 46.4 49.3 30.2 31.1 44.9 18.3 21.1 22.7 20.9 28.6 22.8 22.5 18.8 19.1 19.3 14.2 27.5 31.5 40.6 26.1 18.7 50.8 45.9 14.6 53.8 22.2 1.2 3.8 0.2 4.9 5.8 7.0 12.1 6.8 7.2 4.6 11.9 10.3 8.4 0.4 5.2 3.1 11.7 3.8 4.3 4.3 4.4 5.1 5.2 4.5 5.3 4.5 5.5 4.5 5.0 5.2 4.3 7.0 3.2 4.4 1.3 10.7 102.2 39.6 27.6 31.9 7.6 11.2 16.8 25.8 5.7 14.1 11.0 6.2 38.4 8.7 7.5 39.2 13.5 0.7 9.0 10.8 10.2 8.4 27.4 2.8 10.9 47.6 13.0 7.1 7.3 16.5 9.3 5.3 68.3 21.1 3.3 2.8 8.6 22.4 7.2 13.9 0.5 6.5 7.5 14.2 1.9 5.0 5.4 3.1 1.0 0.7 15.4 6.7 2.6 13.8 36.2 8.0 39.9 9.1 8.5 0.0 9.6 16.7 2.9 10.9 27.7 88.5 36.7 6.9 12.4 18.0 27.8 TIMM9 TIM9A ENSG00000100575 "Translocase of inner mitochondrial membrane 9" Q9Y5J7 14 58408495-58427531 "Predicted intracellular proteins" "Protein transport, Translocation, Transport" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002932 Approved Supported Mitochondria NA NA 78000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" Mitochondria "HPA002932: AB_1080287" "prognostic favorable (8.04e-4)" "unprognostic (8.05e-2)" "unprognostic (3.08e-1)" "unprognostic (1.02e-1)" "unprognostic (2.54e-1)" "unprognostic (3.11e-2)" "prognostic unfavorable (9.89e-5)" "unprognostic (1.51e-1)" "unprognostic (1.84e-1)" "prognostic favorable (6.39e-5)" "unprognostic (3.41e-1)" "unprognostic (7.32e-2)" "unprognostic (7.16e-2)" "unprognostic (4.13e-2)" "unprognostic (1.54e-1)" "unprognostic (1.20e-1)" "unprognostic (5.77e-2)" 42.4 35.8 22.6 18.1 25.1 21.3 40.5 26.9 39.7 37.1 25.7 45.1 23.0 33.6 35.6 29.9 36.1 24.0 34.9 24.0 24.7 46.4 31.8 24.0 28.4 23.8 24.6 48.3 75.7 21.2 27.7 22.3 24.3 32.2 18.0 28.2 35.8 20.5 66.1 33.2 26.8 26.8 24.2 26.1 37.1 22.4 23.3 18.8 30.2 23.6 25.1 39.2 31.4 28.0 71.0 56.7 45.8 46.6 53.0 99.6 63.0 67.6 38.3 55.0 48.7 60.3 74.3 100.4 73.1 38.8 45.2 48.0 63.9 67.0 76.3 68.0 38.5 53.0 36.2 68.8 129.1 78.5 45.6 77.1 86.5 51.4 100.4 80.2 54.4 47.2 82.0 57.8 53.9 120.3 75.5 101.0 38.2 106.2 98.8 63.3 73.8 58.9 70.3 63.1 60.3 34.3 44.6 109.7 126.7 55.2 78.0 45.1 57.4 63.0 87.0 41.4 73.8 40.4 43.1 91.8 50.0 79.1 76.8 8.8 14.8 4.0 14.3 17.0 26.3 28.5 22.5 21.4 21.4 22.3 28.5 27.3 1.6 27.8 19.2 23.2 25.2 12.5 22.6 25.1 26.9 39.7 24.0 24.7 23.8 24.6 24.3 24.2 23.3 28.0 26.8 32.1 20.0 12.7 40.5 35.3 46.4 47.6 38.7 15.9 44.2 55.2 20.7 32.9 26.0 14.7 22.9 80.1 30.7 12.2 72.4 39.1 36.7 21.4 38.5 33.6 25.2 35.3 14.2 54.1 92.9 32.2 25.5 21.9 36.8 36.6 39.7 33.0 61.2 5.0 15.4 43.2 24.4 47.9 29.9 32.7 74.3 30.0 33.8 3.7 47.6 31.6 39.1 8.5 12.2 38.2 30.5 51.6 33.8 57.3 35.3 117.7 15.0 24.0 19.7 49.7 32.3 78.8 22.1 39.2 39.6 73.5 29.9 56.9 53.4 42.8 TMEM11 "C17orf35, PM1, PMI" ENSG00000178307 "Transmembrane protein 11" P17152 17 21197954-21214176 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 81.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051795, HPA062854" Uncertain Supported Mitochondria No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA051795: AB_2681612, HPA062854: AB_2684882" "unprognostic (2.29e-1)" "unprognostic (1.09e-1)" "unprognostic (1.13e-2)" "unprognostic (2.00e-2)" "unprognostic (1.35e-2)" "unprognostic (3.55e-1)" "unprognostic (3.36e-3)" "unprognostic (1.45e-2)" "unprognostic (4.34e-2)" "unprognostic (3.08e-2)" "unprognostic (1.16e-1)" "unprognostic (1.90e-2)" "unprognostic (1.40e-1)" "unprognostic (1.19e-1)" "unprognostic (1.97e-1)" "unprognostic (2.17e-2)" "unprognostic (4.61e-2)" 17.6 11.7 18.9 12.4 19.3 37.7 10.8 21.1 25.1 10.6 18.4 13.9 12.5 11.8 18.6 14.2 9.4 9.0 21.3 19.1 19.9 9.9 9.9 11.8 13.8 20.3 19.3 12.2 30.4 14.9 1.3 17.1 19.8 12.2 10.0 10.9 23.7 9.1 81.3 16.8 14.2 9.8 18.7 11.5 13.2 7.7 19.8 15.8 12.6 54.1 9.8 15.6 1.9 19.8 25.3 27.5 22.7 22.1 33.9 24.1 31.2 38.9 17.7 35.8 31.3 74.5 13.5 27.4 29.7 36.3 29.0 35.0 30.0 35.8 17.9 23.2 46.5 19.8 27.0 32.1 36.8 25.1 22.0 26.5 27.7 36.4 26.2 17.2 22.8 19.3 23.0 9.5 26.9 39.9 37.8 46.6 30.5 68.8 15.3 27.2 49.8 19.6 25.2 21.3 13.8 24.0 17.6 19.0 36.9 87.2 18.4 24.8 21.4 25.1 29.7 42.5 49.3 9.6 13.2 69.3 24.9 31.9 22.6 31.2 70.6 76.2 33.1 58.9 29.6 49.4 33.1 31.8 47.1 47.4 37.0 31.8 58.4 40.8 67.9 38.8 40.3 68.1 18.9 19.3 21.1 25.1 19.1 19.9 20.3 19.3 19.8 18.7 19.8 19.8 35.0 48.1 21.8 5.5 26.0 84.9 61.9 77.7 35.3 32.9 40.2 39.9 49.9 22.8 49.1 36.8 18.8 80.7 36.6 49.4 50.9 55.3 20.7 23.9 23.6 36.8 31.9 51.3 4.4 40.5 80.9 33.9 20.9 29.1 27.3 23.1 32.2 28.1 54.3 23.5 5.1 67.4 73.2 25.3 34.5 16.3 35.8 26.3 40.9 8.4 48.6 31.6 33.0 6.0 8.0 47.4 60.6 57.6 19.9 63.6 55.0 55.9 33.0 39.9 32.9 25.7 42.0 40.4 38.4 34.7 92.6 90.8 28.7 31.3 49.6 80.2 TMEM126B HT007 ENSG00000171204 "Transmembrane protein 126B" Q8IUX1 11 85628573-85636539 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Chaperone "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014480, HPA019186" Uncertain Supported Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA014480: AB_1858083, HPA019186: AB_1858084" "unprognostic (1.11e-1)" "unprognostic (4.97e-2)" "unprognostic (1.10e-1)" "unprognostic (2.79e-2)" "unprognostic (5.67e-1)" "unprognostic (1.44e-1)" "unprognostic (5.55e-3)" "unprognostic (1.22e-1)" "unprognostic (1.45e-2)" "unprognostic (6.70e-3)" "unprognostic (4.42e-2)" "unprognostic (4.30e-2)" "unprognostic (1.94e-2)" "unprognostic (1.78e-1)" "unprognostic (6.50e-2)" "unprognostic (5.86e-2)" "unprognostic (2.66e-2)" 16.1 16.7 29.2 13.0 29.4 6.5 19.3 28.9 38.9 18.2 25.9 21.4 19.6 19.3 30.7 14.3 15.8 17.3 24.7 30.4 31.7 15.3 17.2 15.8 18.7 29.7 30.0 16.4 15.9 11.0 20.8 13.3 30.9 17.0 17.6 18.6 15.7 14.1 16.2 13.8 19.8 21.4 30.1 16.5 17.6 10.9 30.2 16.0 16.8 20.1 17.5 18.6 14.8 32.3 37.9 29.8 33.1 16.0 60.2 49.6 10.6 33.1 36.1 25.6 38.1 84.8 37.1 39.9 72.2 27.1 28.6 45.0 53.2 33.0 23.8 56.5 49.7 30.1 49.1 36.1 35.6 75.4 34.7 37.9 38.3 38.6 47.0 41.1 38.6 49.5 72.5 31.2 58.8 47.9 29.4 91.3 36.1 129.6 50.1 25.0 25.4 33.6 49.5 42.1 30.8 19.1 31.2 24.9 31.9 42.5 50.1 45.4 20.5 38.2 26.5 96.9 35.4 14.6 91.1 47.7 19.4 60.4 20.6 21.5 15.6 7.9 19.0 18.2 24.8 18.3 23.4 23.5 20.1 17.7 23.3 23.4 5.9 23.4 14.5 18.4 25.9 15.9 29.2 29.4 28.9 38.9 30.4 31.7 29.7 30.0 30.9 30.1 30.2 32.3 44.9 22.4 40.7 16.6 34.6 26.1 32.2 80.8 22.8 32.5 36.8 31.1 87.3 54.3 57.2 40.5 14.6 41.0 54.2 33.6 168.3 76.0 5.4 27.2 39.2 46.1 34.6 34.5 19.3 49.0 54.5 45.1 15.8 25.8 42.5 27.8 42.5 43.6 84.1 23.5 20.1 41.3 81.4 47.4 44.6 8.3 66.5 43.5 72.9 9.4 48.8 79.0 80.3 20.6 29.7 51.5 52.8 88.4 22.4 35.3 56.5 162.9 51.3 31.2 39.5 30.0 43.8 34.4 46.8 23.1 36.9 25.2 49.7 45.4 52.0 45.4 TMEM132A "FLJ20539, GBP, HSPA5BP1" ENSG00000006118 "Transmembrane protein 132A" Q24JP5 11 60924460-60937159 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 187.8;choroid plexus: 117.3" "Cell type enhanced" "Detected in many" "Astrocytes: 82.3;Ductal cells: 80.0;Horizontal cells: 254.1;Muller glia cells: 188.8;Rod photoreceptor cells: 165.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 174.1;MCF7: 177.8;SK-BR-3: 176.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051979, HPA060492" Enhanced Supported Approved Mitochondria No No 4100000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 38: EFO-21 - Unknown function" "Cluster 62: Horizontal cells - Visual perception" Mitochondria "HPA051979: AB_2681681, HPA060492: " "unprognostic (2.52e-2)" "unprognostic (2.01e-1)" "unprognostic (3.75e-2)" "prognostic favorable (1.98e-5)" "unprognostic (7.94e-3)" "unprognostic (3.74e-1)" "unprognostic (4.42e-3)" "unprognostic (2.39e-2)" "unprognostic (1.99e-1)" "unprognostic (1.30e-1)" "unprognostic (2.88e-1)" "unprognostic (5.98e-2)" "prognostic unfavorable (1.55e-9)" "unprognostic (3.31e-1)" "unprognostic (9.74e-2)" "unprognostic (1.50e-1)" "unprognostic (8.41e-3)" 7.7 21.0 137.9 8.6 134.3 0.3 7.7 119.4 187.8 12.0 117.3 5.5 2.5 13.6 1.2 19.5 4.8 5.5 13.7 134.1 136.9 13.9 2.1 10.1 1.7 154.5 131.2 18.8 6.8 12.4 23.6 16.6 126.4 9.4 1.0 28.1 25.9 1.8 3.9 6.1 6.0 3.7 123.0 5.7 32.4 6.7 144.6 1.3 4.8 3.1 5.4 4.2 9.2 114.7 37.0 50.7 44.1 88.0 3.6 1.7 78.1 27.0 84.5 24.6 20.3 18.0 33.3 0.3 174.1 7.8 79.9 67.6 10.3 46.0 9.5 0.5 14.8 1.1 33.3 32.7 30.8 0.5 1.3 7.7 8.6 45.8 7.1 38.7 42.1 7.0 2.3 2.3 7.8 177.8 0.9 0.2 58.5 1.2 26.9 0.4 18.6 4.2 36.4 18.7 43.7 104.1 19.3 176.4 16.7 22.3 123.7 0.6 49.4 9.5 43.2 2.7 52.3 0.4 0.3 2.1 78.5 0.1 46.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 137.9 134.3 119.4 187.8 134.1 136.9 154.5 131.2 126.4 123.0 144.6 114.7 11.8 0.0 0.0 82.3 0.6 1.3 2.7 56.2 5.7 62.8 17.1 11.7 0.8 4.3 22.2 5.5 18.8 31.4 0.1 0.7 1.9 80.0 0.5 12.4 7.0 11.9 15.6 0.0 22.6 13.3 28.7 7.7 9.2 27.7 0.0 57.5 11.4 0.0 3.3 254.1 29.1 2.7 20.3 0.3 1.0 1.0 1.8 0.7 0.0 7.5 3.1 188.8 0.0 12.1 3.3 63.2 1.6 3.4 0.0 9.7 0.0 0.4 4.0 165.3 6.6 4.4 15.2 1.2 4.0 5.7 0.9 27.1 0.3 19.2 2.3 7.2 TMEM144 FLJ11155 ENSG00000164124 "Transmembrane protein 144" Q7Z5S9 4 158201604-158255416 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "brain: 418.0" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 994.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.1;plasmacytoid DC: 2.2" "Group enriched" "Detected in many" 10 "dendritic cells: 2.2;monocytes: 1.4" "Cell line enhanced" "Detected in many" "BEWO: 36.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063554 Approved Mitochondria NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 28: BEWO - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA063554: AB_2685039" "unprognostic (1.26e-2)" "unprognostic (7.05e-2)" "unprognostic (2.06e-2)" "prognostic favorable (2.89e-4)" "unprognostic (2.90e-1)" "unprognostic (1.71e-5)" "unprognostic (8.27e-2)" "unprognostic (3.32e-1)" "unprognostic (2.21e-1)" "unprognostic (3.33e-2)" "prognostic unfavorable (8.48e-4)" "unprognostic (9.34e-2)" "unprognostic (1.13e-2)" "unprognostic (1.35e-1)" "unprognostic (9.26e-2)" "unprognostic (3.88e-2)" "unprognostic (4.05e-2)" 8.6 12.9 91.0 3.6 235.8 3.1 15.4 164.3 134.4 7.6 15.3 14.4 29.4 6.1 15.6 5.4 6.8 12.5 14.9 101.1 122.5 3.8 3.2 6.3 2.3 204.2 158.6 13.5 7.4 4.6 1.3 6.5 201.8 9.0 15.9 0.6 5.9 10.9 2.8 3.4 20.7 7.1 133.8 4.0 11.2 27.0 163.9 1.9 16.9 2.6 1.6 6.6 2.6 418.0 4.7 12.1 0.2 2.6 8.6 11.8 36.5 1.9 3.9 1.7 2.8 15.1 17.8 0.0 2.8 0.6 10.0 2.2 5.1 16.7 2.4 0.0 5.5 8.5 3.0 13.5 2.8 10.7 2.3 8.9 20.0 7.0 3.0 0.5 9.7 1.7 5.5 0.2 12.8 5.1 0.0 0.0 3.2 15.1 2.9 0.0 0.0 0.4 4.2 12.3 1.9 0.0 0.5 19.6 4.2 7.1 12.6 2.4 1.8 3.9 2.7 0.7 2.1 0.0 1.1 0.9 5.4 1.4 3.1 0.0 1.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.1 0.3 2.2 0.0 0.3 91.0 235.8 164.3 134.4 101.1 122.5 204.2 158.6 201.8 133.8 163.9 418.0 2.9 9.6 9.1 53.2 0.3 3.1 7.7 5.2 2.8 0.9 12.4 10.7 12.7 12.8 8.4 0.0 0.0 13.7 1.5 36.6 0.0 15.4 231.8 14.5 8.6 4.8 4.9 3.0 10.9 13.3 6.5 4.4 14.8 24.5 4.5 14.6 4.6 1.2 29.0 0.0 12.5 21.4 8.2 20.8 5.0 98.2 10.5 12.9 3.6 12.2 10.6 1.3 0.0 5.5 994.4 9.0 18.9 9.1 0.2 3.5 44.1 6.4 8.8 0.2 0.0 8.5 2.6 3.0 2.2 5.8 5.1 8.8 0.9 6.8 18.6 6.4 TMEM176A "HCA112, MS4B1" ENSG00000002933 "Transmembrane protein 176A" Q96HP8 7 150800403-150805118 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 377.7;liver: 1170.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 1043.9;Paneth cells: 779.4;Proximal enterocytes: 1294.5;Proximal tubular cells: 1103.9" "Cancer enhanced" "Detected in all" "liver cancer: 210.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 146.5;intermediate monocyte: 98.4" "Lineage enriched" "Detected in many" 5 "monocytes: 146.5" "Cell line enriched" "Detected in some" 31 "HSkMC: 730.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008770 Approved Approved Mitochondria NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA008770: AB_2256120" "unprognostic (4.70e-2)" "unprognostic (7.71e-2)" "unprognostic (5.71e-3)" "unprognostic (6.09e-2)" "unprognostic (3.96e-3)" "unprognostic (1.44e-2)" "unprognostic (2.51e-1)" "unprognostic (2.32e-1)" "unprognostic (4.19e-2)" "unprognostic (1.99e-1)" "unprognostic (1.47e-2)" "unprognostic (4.37e-2)" "unprognostic (4.79e-1)" "unprognostic (1.23e-2)" "unprognostic (1.98e-2)" "unprognostic (2.64e-1)" "unprognostic (4.91e-2)" 76.6 33.1 46.5 124.8 48.0 6.8 49.3 49.2 50.8 45.7 39.1 143.9 113.2 18.6 17.9 28.5 48.9 129.8 90.9 43.6 56.2 377.7 1170.6 58.5 85.6 64.0 56.2 104.7 29.8 3.9 11.6 66.6 58.2 26.5 151.3 20.6 24.2 15.9 6.4 20.6 203.1 50.2 61.3 51.0 48.7 6.1 49.9 15.5 21.3 17.4 66.0 98.0 54.5 63.9 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 3.5 14.2 0.2 0.6 0.0 0.3 1.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.3 0.3 730.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.6 0.9 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 23.3 0.0 0.0 2.7 0.5 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.0 146.5 12.6 0.3 98.4 0.4 2.1 0.1 0.2 30.9 0.0 0.2 0.0 1.8 0.3 46.0 2.4 0.4 53.3 46.5 48.0 49.2 50.8 43.6 56.2 64.0 56.2 58.2 61.3 49.9 63.9 15.8 0.0 5.2 3.9 9.8 7.4 0.4 0.9 5.2 56.2 40.6 63.8 24.9 118.7 10.9 200.5 4.2 0.6 2.0 348.5 152.6 64.6 0.3 4.9 14.8 20.5 74.1 6.6 0.0 27.2 0.6 185.3 17.9 2.5 29.0 29.9 23.2 1043.9 52.2 0.0 0.2 237.7 73.2 56.9 26.2 1.5 60.3 109.4 5.4 1.9 313.0 80.8 1.0 1.0 0.0 56.0 779.4 7.5 0.9 1.8 1294.5 1103.9 10.6 5.3 0.0 5.7 32.8 0.9 1.6 2.9 8.4 1.4 6.4 0.1 262.4 2.7 TMEM179 "C14orf90, FLJ42486, TMEM179A" ENSG00000258986 "Transmembrane protein 179" Q6ZVK1 14 104474678-104605647 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 31.5;pituitary gland: 88.1" "Group enriched" "Detected in some" 5 "Bipolar cells: 58.1;Horizontal cells: 65.6" "Group enriched" "Detected in some" 4 "glioma: 2.7;pancreatic cancer: 3.1;testis cancer: 2.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 8.8;SCLC-21H: 37.3;SH-SY5Y: 11.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002942 Uncertain Mitochondria NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" Mitochondria "HPA002942: AB_1078113" "unprognostic (8.65e-2)" "unprognostic (8.24e-2)" "unprognostic (3.10e-2)" "unprognostic (1.29e-2)" "unprognostic (1.90e-2)" "unprognostic (1.08e-2)" "unprognostic (3.46e-2)" "unprognostic (2.69e-1)" "unprognostic (1.31e-1)" "unprognostic (2.09e-1)" "unprognostic (2.82e-3)" "unprognostic (1.09e-1)" "unprognostic (1.89e-4)" "unprognostic (8.68e-3)" "unprognostic (1.56e-1)" "unprognostic (9.71e-6)" "unprognostic (1.70e-2)" 0.2 11.4 18.9 0.3 19.3 0.0 0.1 12.0 29.7 0.1 4.6 3.8 0.2 0.1 0.4 0.1 0.3 0.1 1.0 17.8 24.6 0.5 0.5 0.1 0.0 25.9 24.9 0.1 4.0 0.1 88.1 0.8 31.5 0.8 0.2 6.2 0.1 0.1 0.1 0.0 1.4 0.3 12.5 0.0 1.3 5.2 18.8 0.0 0.1 0.0 0.0 0.1 0.7 20.5 0.0 0.5 0.3 0.8 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 37.3 11.6 0.0 0.3 0.0 0.1 0.8 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.9 19.3 12.0 29.7 17.8 24.6 25.9 24.9 31.5 12.5 18.8 20.5 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 58.1 0.0 0.0 1.2 0.0 0.0 0.0 4.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 12.0 0.0 0.0 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.1 65.6 12.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.0 0.0 1.5 0.0 7.5 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.1 0.7 3.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 TMEM71 FLJ33069 ENSG00000165071 "Transmembrane protein 71" Q6P5X7 8 132685007-132760712 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 33.5;heart muscle: 37.1" "Cell type enhanced" "Detected in many" "dendritic cells: 39.9;Kupffer cells: 20.7;Langerhans cells: 25.7;Macrophages: 26.2;monocytes: 25.5;NK-cells: 54.6;T-cells: 35.9" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 4 "cerebral cortex: 9.7" "Immune cell enhanced" "Detected in all" "neutrophil: 269.0" "Lineage enriched" "Detected in all" 5 "granulocytes: 269.0" "Cell line enhanced" "Detected in many" "BJ hTERT+: 12.7;HDLM-2: 54.5;Karpas-707: 11.1;U-937: 31.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA058401, HPA070655" Uncertain Enhanced Mitochondria NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Mitochondria "HPA058401: AB_2683707, HPA070655: AB_2686292" "unprognostic (1.39e-3)" "unprognostic (7.27e-2)" "unprognostic (8.82e-2)" "unprognostic (3.10e-3)" "unprognostic (7.94e-2)" "unprognostic (3.91e-3)" "unprognostic (4.18e-2)" "unprognostic (5.06e-2)" "unprognostic (1.53e-1)" "unprognostic (1.71e-1)" "unprognostic (1.63e-1)" "unprognostic (1.62e-1)" "unprognostic (8.83e-2)" "unprognostic (1.90e-2)" "unprognostic (6.29e-3)" "unprognostic (4.39e-2)" "unprognostic (2.73e-1)" 5.6 2.0 1.0 13.1 1.3 33.5 8.5 1.0 9.7 2.5 2.2 11.3 2.2 1.3 1.1 2.8 1.9 5.5 37.1 1.1 1.8 2.6 3.9 8.2 13.2 1.6 1.3 1.0 2.4 0.7 1.1 1.8 2.1 2.0 3.4 0.5 5.7 2.2 1.6 1.1 7.3 3.6 1.1 18.4 2.8 1.0 2.4 19.2 2.0 4.6 10.6 4.6 1.9 1.6 0.4 0.0 4.9 0.0 0.0 0.0 0.0 1.3 12.7 0.5 0.9 0.0 0.0 0.1 0.6 4.1 0.1 0.0 0.0 0.3 1.5 54.5 0.0 0.0 0.0 0.0 0.3 3.6 0.0 0.1 0.0 0.1 2.0 1.4 1.0 6.7 0.0 11.1 2.4 0.0 2.9 2.2 1.2 0.0 0.4 0.1 1.8 0.8 4.8 0.1 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.1 2.1 0.5 0.9 1.2 5.7 0.1 2.9 0.0 9.0 31.6 3.7 61.9 55.9 101.6 31.3 16.1 57.9 6.6 22.8 22.2 33.7 4.7 33.9 25.1 269.0 12.9 14.7 1.1 3.0 39.0 1.0 1.3 1.0 9.7 1.1 1.8 1.6 1.3 2.1 1.1 2.4 1.6 0.5 0.0 3.0 0.0 6.9 0.9 1.0 2.5 0.6 0.0 4.2 2.7 15.9 0.0 5.5 0.0 0.0 0.0 39.9 0.1 0.0 0.0 6.5 0.1 0.3 1.5 0.0 8.8 0.5 0.0 0.0 4.1 1.1 0.2 1.3 0.0 3.3 0.2 3.2 0.0 1.3 0.2 0.0 20.7 25.7 5.1 0.0 26.2 5.4 17.8 25.5 1.9 54.6 0.0 0.1 0.1 0.0 0.0 11.3 0.1 0.0 0.4 2.9 0.0 0.0 3.7 0.8 0.0 0.6 0.4 0.3 0.3 35.9 0.1 0.0 4.5 TMIGD1 "TMIGD, UNQ9372" ENSG00000182271 "Transmembrane and immunoglobulin domain containing 1" Q6UXZ0 17 30316333-30334059 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "intestine: 140.5" "Group enriched" "Detected in some" 28 "Distal enterocytes: 291.9;Paneth cells: 125.5;Proximal enterocytes: 476.6" "Cancer enriched" "Detected in single" 5 "colorectal cancer: 1.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA021946 Approved Mitochondria NA NA "Cluster 9: Intestine - Unknown function" "Cluster 45: Enterocytes - Digestion" Mitochondria "HPA021946: AB_1858140" "unprognostic (1.28e-1)" "unprognostic (1.30e-1)" "unprognostic (1.61e-1)" 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 80.5 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 98.5 0.0 0.0 0.0 0.0 0.0 140.5 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 291.9 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 125.5 0.0 0.0 0.0 476.6 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 7.5 0.0 TMLHE "BBOX2, FLJ10727, TMLH, XAP130" ENSG00000185973 "Trimethyllysine hydroxylase, epsilon" Q9NVH6 X 155489011-155719098 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carnitine biosynthesis" "Dioxygenase, Oxidoreductase" "Autism, Autism spectrum disorder, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 51.5;Oligodendrocyte precursor cells: 47.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034589, HPA040331" Approved Supported Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 38: EFO-21 - Unknown function" "Cluster 68: Oligodendrocytes - Mixed function" Mitochondria "HPA034589: AB_10670571, HPA040331: AB_2676929" "unprognostic (1.98e-1)" "unprognostic (9.15e-2)" "unprognostic (3.04e-1)" "unprognostic (5.41e-2)" "unprognostic (6.66e-3)" "unprognostic (1.10e-3)" "unprognostic (6.50e-2)" "unprognostic (1.00e-1)" "unprognostic (3.27e-1)" "unprognostic (4.08e-2)" "unprognostic (1.20e-3)" "unprognostic (6.97e-2)" "prognostic favorable (3.68e-6)" "unprognostic (1.69e-1)" "unprognostic (5.74e-2)" "unprognostic (2.73e-1)" "unprognostic (7.75e-2)" 11.7 10.2 7.1 6.6 7.4 8.4 11.3 9.0 8.0 11.3 8.1 11.6 11.8 9.4 10.4 10.3 9.9 8.0 25.3 6.7 7.7 16.7 18.8 5.6 7.0 8.5 8.2 12.0 9.5 18.9 5.4 8.4 8.5 6.6 12.5 10.9 12.7 9.7 32.0 5.9 11.2 12.3 8.3 8.7 9.1 2.9 7.3 8.9 10.5 33.4 7.6 8.2 6.6 9.8 25.0 11.9 9.8 28.6 11.8 18.1 0.0 9.9 14.6 12.3 32.4 8.7 13.9 0.0 38.9 17.6 28.2 13.4 21.2 9.7 13.9 10.3 14.3 11.3 19.5 10.2 16.4 10.5 7.6 19.5 20.0 13.6 20.8 18.2 19.5 15.5 15.8 9.0 20.5 9.3 12.8 11.8 3.0 21.6 0.1 12.7 15.5 9.4 15.0 8.5 9.2 13.7 9.3 0.5 11.2 10.5 10.6 11.9 16.5 10.3 9.7 20.4 12.4 11.0 12.6 9.6 12.4 16.4 9.6 3.4 12.6 14.7 4.6 14.9 3.5 8.1 5.0 3.9 13.1 10.6 6.5 5.7 18.2 6.2 21.5 6.1 5.5 5.8 7.1 7.4 9.0 8.0 6.7 7.7 8.5 8.2 8.5 8.3 7.3 9.8 6.7 0.0 2.3 27.1 10.1 5.2 12.1 14.4 9.6 4.0 5.2 7.5 7.2 7.2 9.7 9.2 0.0 8.8 6.5 7.9 23.5 10.7 0.0 6.8 7.4 6.2 6.1 14.3 22.2 7.6 6.8 10.2 9.2 7.3 10.1 8.1 4.2 12.0 12.4 0.0 29.5 7.3 4.1 16.1 10.4 0.5 8.4 12.1 12.4 51.5 13.1 7.6 10.3 47.7 25.5 8.5 7.3 5.7 5.6 4.3 17.4 17.0 9.5 5.4 0.0 5.9 9.5 0.3 2.5 7.6 4.1 6.7 8.0 10.5 6.5 11.0 TOMM20 "KIAA0016, MAS20, MOM19, TOM20" ENSG00000173726 "Translocase of outer mitochondrial membrane 20" Q15388 1 235109341-235128837 "Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005585, HPA011562" Supported Enhanced Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 32: Non-specific - Translation" Mitochondria "CAB005585: AB_628381, HPA011562: AB_1080326" "unprognostic (1.30e-1)" "unprognostic (3.08e-3)" "unprognostic (1.66e-2)" "unprognostic (4.49e-2)" "unprognostic (8.65e-3)" "unprognostic (1.17e-2)" "unprognostic (7.09e-2)" "unprognostic (3.28e-1)" "unprognostic (3.18e-2)" "unprognostic (1.75e-1)" "unprognostic (1.16e-3)" "unprognostic (5.05e-2)" "unprognostic (7.08e-3)" "unprognostic (2.33e-2)" "unprognostic (1.17e-1)" "unprognostic (1.11e-1)" "unprognostic (3.97e-1)" 71.5 83.5 80.0 39.2 89.0 96.6 130.8 63.0 111.9 82.9 63.4 64.3 61.0 83.5 91.6 67.8 95.6 48.3 86.4 91.7 79.9 100.4 88.3 60.2 53.7 76.9 71.5 119.5 103.1 111.6 54.3 68.2 81.2 80.5 67.9 51.3 125.1 70.1 83.0 82.5 54.5 59.3 81.7 47.2 69.4 32.8 84.1 57.1 142.9 82.4 56.6 66.4 56.7 83.3 198.7 102.4 131.6 111.6 101.4 202.6 203.5 138.8 119.3 127.9 92.5 133.1 135.6 239.3 180.1 121.0 36.1 154.0 147.8 135.0 166.9 57.9 314.8 146.2 126.2 253.9 169.2 331.3 84.2 182.3 180.8 128.6 175.4 173.0 140.7 92.2 312.1 85.9 141.9 58.2 141.9 149.4 296.6 131.2 54.9 170.9 100.3 312.6 144.5 140.2 172.5 402.8 108.0 149.2 306.7 53.6 230.9 358.6 125.6 111.5 67.5 143.0 299.6 201.2 203.1 172.4 131.2 155.4 193.1 37.7 18.8 6.5 19.4 19.7 23.6 23.0 24.8 24.3 22.7 18.2 30.1 24.2 5.6 15.8 22.9 30.6 23.7 21.5 80.0 89.0 63.0 111.9 91.7 79.9 76.9 71.5 81.2 81.7 84.1 83.3 167.2 137.8 163.5 25.1 201.9 267.4 254.9 158.5 251.6 49.9 299.2 307.0 137.8 160.2 151.3 49.7 29.2 171.3 195.5 98.3 160.4 161.6 318.4 180.2 254.3 156.8 160.5 127.0 69.0 211.2 462.5 139.9 121.3 216.9 157.7 146.4 129.9 160.1 159.9 50.5 61.1 273.4 99.7 197.7 164.6 354.0 155.0 175.7 149.4 28.1 187.5 145.4 116.4 26.2 55.8 220.1 172.3 153.4 176.7 340.4 247.0 223.5 99.7 60.9 105.2 201.4 207.5 186.5 71.1 273.3 286.1 199.5 179.5 196.1 272.6 333.4 TOMM22 TOM22 ENSG00000100216 "Translocase of outer mitochondrial membrane 22" Q9NS69 22 38681957-38685421 "Predicted membrane proteins" "Protein transport, Translocation, Transport" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003037 Supported Enhanced Mitochondria NA NA 230000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA003037: AB_1080329" "unprognostic (5.54e-2)" "unprognostic (5.04e-3)" "unprognostic (2.74e-3)" "unprognostic (1.48e-2)" "unprognostic (1.32e-1)" "unprognostic (1.85e-2)" "prognostic unfavorable (2.90e-5)" "unprognostic (1.01e-1)" "unprognostic (4.28e-1)" "unprognostic (7.01e-2)" "unprognostic (1.64e-2)" "unprognostic (7.39e-2)" "unprognostic (5.44e-2)" "unprognostic (5.32e-2)" "unprognostic (1.99e-1)" "unprognostic (7.86e-2)" "unprognostic (1.64e-1)" 19.6 21.1 27.6 19.0 28.5 30.4 17.2 29.0 29.7 16.6 29.4 22.6 24.5 15.5 19.2 28.4 20.5 11.5 29.1 27.7 28.7 23.9 28.5 12.7 25.3 28.6 28.2 19.1 21.1 22.5 9.9 15.7 28.9 15.1 27.6 8.6 21.4 12.5 34.6 22.1 19.4 19.4 28.0 17.0 20.3 17.0 29.6 27.0 17.1 31.0 30.5 23.8 17.8 28.3 61.7 35.5 53.4 56.9 38.6 35.7 57.5 49.7 34.3 71.1 53.1 65.0 35.8 62.0 39.9 48.9 48.7 49.7 81.8 75.2 56.7 53.8 89.9 83.4 25.2 63.0 50.2 223.2 56.7 49.0 52.6 64.1 41.6 37.0 52.9 59.5 64.4 48.2 48.1 47.9 67.7 103.3 82.0 80.8 71.5 73.9 69.2 58.8 47.7 44.3 62.4 41.3 58.1 72.7 59.1 36.1 50.5 73.1 54.3 43.4 81.8 40.1 76.2 65.9 85.7 94.3 54.3 76.0 60.6 12.9 50.9 16.6 35.4 51.1 44.9 48.7 37.8 37.5 66.4 37.8 38.0 41.4 5.0 42.7 43.1 58.0 48.7 72.8 27.6 28.5 29.0 29.7 27.7 28.7 28.6 28.2 28.9 28.0 29.6 28.3 62.4 25.6 30.4 4.2 123.3 167.0 134.8 158.7 109.8 30.1 79.5 67.7 70.2 82.9 68.0 71.7 16.7 180.0 89.7 74.8 223.0 135.3 139.6 50.5 58.8 77.1 105.1 98.8 7.3 133.2 232.1 70.4 65.7 50.6 74.3 100.3 69.9 101.4 163.9 28.6 8.4 133.5 99.7 120.2 130.7 143.2 55.3 93.3 113.8 4.7 153.2 76.1 105.0 4.5 8.7 116.2 85.2 54.5 130.3 153.4 116.2 245.9 35.2 33.7 72.3 73.3 76.9 130.1 148.2 185.5 210.3 135.6 102.6 100.9 189.7 158.7 TOMM5 "bA613M10.3, C9orf105, Tom5" ENSG00000175768 "Translocase of outer mitochondrial membrane 5" Q8N4H5 9 37582646-37592604 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048712 Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA048712: AB_2680499" "unprognostic (1.81e-2)" "unprognostic (1.96e-1)" "unprognostic (3.37e-2)" "unprognostic (3.34e-2)" "unprognostic (2.02e-1)" "unprognostic (2.82e-2)" "prognostic unfavorable (2.09e-4)" "unprognostic (9.89e-3)" "prognostic unfavorable (5.49e-4)" "prognostic favorable (2.37e-4)" "unprognostic (7.80e-2)" "unprognostic (1.60e-1)" "unprognostic (1.25e-1)" "unprognostic (3.23e-2)" "unprognostic (3.07e-2)" "unprognostic (2.37e-1)" "unprognostic (9.09e-2)" 90.0 92.6 69.9 62.8 72.2 66.4 71.9 71.1 84.8 62.2 68.9 84.2 74.0 64.9 62.0 89.1 58.7 47.2 83.9 71.3 75.9 114.5 87.5 57.0 83.0 70.7 73.5 63.7 90.3 52.4 66.3 39.2 77.0 58.9 60.2 40.2 70.1 46.0 129.4 63.3 62.2 55.9 72.9 75.5 72.7 65.2 70.7 72.0 65.2 89.6 78.8 79.8 65.2 70.7 353.2 400.4 234.3 211.2 265.7 258.9 128.9 262.5 169.4 252.1 268.6 431.4 142.2 240.3 208.4 253.7 254.4 119.0 212.0 316.2 262.6 338.5 329.0 212.1 535.7 630.0 216.1 350.6 133.7 224.9 170.4 277.4 273.5 118.7 293.5 264.1 524.9 261.5 261.1 282.3 297.2 306.9 407.7 296.2 249.0 247.9 195.2 353.3 294.0 218.7 202.4 184.7 134.9 181.6 201.5 198.2 127.0 405.4 198.8 173.3 369.7 273.9 411.8 97.5 312.3 407.8 211.4 300.9 272.0 77.3 155.2 74.5 202.0 177.4 252.1 309.9 246.7 227.8 196.8 260.6 251.9 232.8 17.8 216.5 154.3 218.4 221.2 279.7 69.9 72.2 71.1 84.8 71.3 75.9 70.7 73.5 77.0 72.9 70.7 70.7 31.7 28.9 33.4 16.0 95.5 112.3 49.9 72.8 138.3 5.0 51.2 66.5 20.8 47.1 54.3 46.0 12.5 24.5 41.6 36.5 80.3 55.6 218.3 43.3 49.1 49.8 18.1 120.5 14.2 127.2 55.6 45.9 122.9 46.2 46.2 22.1 50.0 159.2 66.6 1.7 14.9 50.8 52.9 52.7 48.6 181.2 35.1 55.0 62.2 6.5 58.3 10.5 32.0 6.6 11.0 109.2 32.6 31.2 178.3 67.7 75.3 215.0 51.7 8.8 0.0 40.5 42.2 87.4 24.2 235.4 146.3 25.2 73.3 20.8 53.6 55.9 TOMM6 "OBTP, Tom6" ENSG00000214736 "Translocase of outer mitochondrial membrane 6" Q96B49 6 41787662-41789898 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Alveolar cells type 2: 18.7;Astrocytes: 31.0;Club cells: 10.5;Excitatory neurons: 16.5;granulocytes: 8.8;Inhibitory neurons: 15.5;Microglial cells: 10.3;Oligodendrocyte precursor cells: 12.1;Oligodendrocytes: 26.3;Respiratory ciliated cells: 16.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 2247.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004801 Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 11: Alveolar cells - Smell perception" Mitochondria "HPA004801: AB_1859553" 176.9 267.7 240.1 136.8 246.2 228.0 219.9 246.7 320.8 158.4 254.4 158.2 101.8 139.7 270.3 234.0 162.9 96.2 285.9 245.2 248.1 271.8 232.2 143.6 207.5 243.9 242.9 179.0 208.3 193.3 143.2 141.2 245.5 177.6 177.1 128.8 166.1 120.3 272.4 196.4 134.8 132.3 250.1 200.3 170.2 133.9 245.5 192.6 161.4 232.8 260.9 166.5 153.9 254.2 647.0 319.0 372.7 382.2 337.6 398.5 391.6 312.2 324.8 390.3 380.4 559.4 295.3 289.3 373.3 370.1 445.4 201.2 597.3 523.3 505.9 409.8 619.8 525.5 382.4 928.6 264.9 708.7 328.6 362.0 529.4 431.8 366.2 277.1 480.4 407.1 1335.5 350.4 481.7 766.0 519.4 1124.8 329.7 2247.1 312.6 373.3 234.1 865.3 540.1 329.3 327.6 458.7 213.0 369.5 548.5 389.7 451.6 1411.8 342.8 272.0 340.9 274.2 478.8 318.6 751.6 1314.8 155.9 586.7 362.7 119.3 439.5 259.3 291.7 448.3 283.7 419.2 294.4 291.2 454.1 380.7 329.3 324.1 55.9 230.6 475.3 474.6 303.3 674.5 240.1 246.2 246.7 320.8 245.2 248.1 243.9 242.9 245.5 250.1 245.5 254.2 0.0 3.2 18.7 31.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.5 0.0 0.0 0.5 0.0 0.0 8.8 0.0 0.0 0.0 0.0 0.0 15.5 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 10.3 0.0 0.0 0.0 12.1 26.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 TOMM70 "KIAA0719, Tom70, TOMM70A" ENSG00000154174 "Translocase of outer mitochondrial membrane 70" O94826 3 100363431-100401089 "Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 34.9;Extravillous trophoblasts: 33.2;Proximal tubular cells: 48.6;Theca cells: 32.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014589, CAB017156, HPA048020" Enhanced Enhanced Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "CAB017156: , HPA014589: AB_1858185, HPA048020: AB_2680234" "unprognostic (2.74e-2)" "unprognostic (2.25e-1)" "unprognostic (2.57e-2)" "unprognostic (2.69e-3)" "unprognostic (2.12e-2)" "unprognostic (5.96e-2)" "unprognostic (2.06e-3)" "unprognostic (5.01e-2)" "unprognostic (9.86e-2)" "unprognostic (1.21e-1)" "unprognostic (9.73e-3)" "unprognostic (5.38e-2)" "unprognostic (2.62e-3)" "unprognostic (1.73e-1)" "unprognostic (3.53e-1)" "unprognostic (3.34e-2)" "unprognostic (6.98e-3)" 29.7 23.1 21.8 19.5 38.7 16.6 31.5 20.6 24.4 19.8 19.1 27.7 29.3 24.5 21.3 28.9 20.4 16.1 38.8 23.6 23.0 36.8 61.7 15.9 22.2 21.3 18.6 30.8 26.8 27.2 14.8 23.4 21.9 26.4 29.8 45.4 21.9 26.9 66.4 19.8 24.4 26.7 17.9 19.2 21.5 19.6 22.9 29.6 30.1 76.1 25.9 27.3 17.8 19.5 70.2 48.3 39.8 57.9 55.4 60.0 52.0 57.9 49.6 52.2 53.8 68.7 39.0 83.2 49.9 49.7 46.6 67.4 73.1 53.4 76.7 31.6 33.7 95.2 30.3 67.3 34.6 117.2 41.8 53.7 48.6 46.5 75.6 46.5 38.8 40.1 69.2 65.6 63.3 51.9 79.6 47.5 55.2 107.4 101.2 72.0 80.9 89.0 42.6 52.2 72.2 60.1 42.3 67.0 77.9 38.2 87.1 65.8 35.2 45.5 60.3 25.8 44.0 71.1 108.8 139.1 44.1 70.0 35.2 1.1 1.0 1.2 1.9 1.1 2.3 2.0 2.3 2.0 1.4 1.4 2.3 2.5 0.2 2.7 1.3 1.4 1.0 0.8 21.8 38.7 20.6 24.4 23.6 23.0 21.3 18.6 21.9 17.9 22.9 19.5 24.2 6.4 25.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 30.0 20.2 0.0 0.0 11.2 14.7 0.0 26.8 11.5 0.0 11.7 19.0 0.0 13.8 34.9 10.0 0.0 0.0 0.0 20.1 33.2 12.9 0.0 25.4 7.6 27.1 0.0 0.0 22.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 5.7 0.0 0.0 0.0 0.0 22.5 0.0 0.0 2.3 0.0 0.0 48.6 10.2 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.0 16.3 6.3 32.9 0.0 0.0 TOP1MT ENSG00000184428 "DNA topoisomerase I mitochondrial" Q969P6 8 143304384-143359979 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "DNA-binding, Isomerase, Topoisomerase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "MOLT-4: 197.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001915, HPA021542" Approved Supported Mitochondria NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 32: Non-specific - Translation" Mitochondria "HPA001915: AB_1080331, HPA021542: AB_1858186" "unprognostic (5.02e-3)" "unprognostic (3.79e-2)" "unprognostic (6.57e-2)" "unprognostic (6.92e-3)" "unprognostic (2.32e-2)" "unprognostic (1.04e-2)" "unprognostic (3.05e-3)" "unprognostic (1.44e-1)" "unprognostic (1.44e-1)" "unprognostic (1.13e-1)" "unprognostic (1.50e-2)" "unprognostic (4.42e-2)" "prognostic unfavorable (1.52e-7)" "unprognostic (3.66e-2)" "unprognostic (3.62e-2)" "unprognostic (8.55e-3)" "unprognostic (5.66e-3)" 14.0 17.4 7.3 9.4 6.1 48.2 13.7 2.5 7.8 23.2 4.0 12.6 7.6 11.7 4.8 18.4 13.4 9.2 7.6 8.5 5.8 14.4 30.3 10.5 12.0 7.0 4.7 32.1 18.9 10.1 9.2 7.4 7.1 13.2 9.7 2.0 14.2 8.1 7.3 22.6 11.6 7.8 2.9 12.6 12.9 23.4 5.4 21.4 21.9 3.4 11.4 17.8 19.1 6.4 25.5 38.3 15.8 59.4 22.0 24.5 28.1 11.6 14.8 20.5 21.1 48.4 35.8 74.2 42.6 16.2 14.7 26.8 33.8 21.3 17.6 29.5 52.4 65.6 21.5 49.5 24.8 44.4 68.4 25.1 22.3 17.4 24.8 17.7 25.0 21.1 80.5 28.2 18.3 106.3 197.8 87.9 27.6 54.9 65.4 24.7 20.7 112.2 15.3 40.4 28.1 34.1 33.2 29.3 61.7 19.3 19.3 72.5 16.5 14.3 57.7 16.4 30.2 15.2 17.0 38.0 24.1 64.9 17.4 31.4 10.5 0.5 6.2 6.3 6.3 28.9 11.3 8.6 35.3 14.4 24.2 18.8 0.7 0.4 1.2 30.9 3.2 9.2 7.3 6.1 2.5 7.8 8.5 5.8 7.0 4.7 7.1 2.9 5.4 6.4 11.4 6.4 8.6 3.3 11.9 23.7 32.3 13.1 14.2 1.2 15.3 11.6 3.3 10.0 10.5 9.2 0.0 11.7 7.3 6.7 7.9 11.4 29.3 3.9 10.9 7.7 4.9 41.3 2.5 9.3 23.6 8.9 5.6 5.8 7.0 24.7 6.4 12.1 11.1 3.3 3.5 11.3 2.0 8.8 24.9 11.1 8.7 9.4 21.4 0.0 9.3 1.4 2.1 1.5 2.9 7.1 11.2 4.5 6.1 29.7 2.8 15.8 3.1 0.2 6.6 13.5 10.0 31.3 36.4 17.8 23.9 10.1 8.6 21.4 20.8 22.8 TRAM1L1 MGC26568 ENSG00000174599 "Translocation associated membrane protein 1 like 1" Q8N609 4 117083554-117085576 "Predicted membrane proteins, Transporters" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 6.8;Oligodendrocyte precursor cells: 8.0;Oligodendrocytes: 13.5;Spermatogonia: 6.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SH-SY5Y: 9.0;U-138 MG: 11.0;U-266/70: 9.1" "Low region specificity" "Detected in all" HPA044560 Uncertain Uncertain Mitochondria NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA044560: AB_10796097" "unprognostic (9.06e-2)" "unprognostic (2.87e-2)" "unprognostic (4.40e-2)" "unprognostic (2.17e-3)" "unprognostic (9.77e-2)" "unprognostic (2.37e-2)" "unprognostic (5.97e-2)" "unprognostic (3.02e-1)" "unprognostic (1.14e-1)" "unprognostic (3.25e-1)" "unprognostic (1.09e-3)" "unprognostic (1.56e-2)" "unprognostic (2.76e-2)" "unprognostic (1.68e-2)" "unprognostic (1.62e-1)" "unprognostic (4.82e-3)" "unprognostic (1.23e-2)" 1.2 2.4 4.7 0.5 6.0 0.0 4.2 5.4 7.0 2.5 2.9 1.2 0.4 1.9 6.0 0.8 3.9 1.7 1.0 4.9 6.1 6.9 0.1 1.6 0.5 5.7 5.5 2.2 2.9 2.4 3.2 0.6 6.1 4.3 1.1 5.5 1.4 2.5 0.3 2.4 0.6 2.0 5.5 0.6 1.9 3.6 6.0 0.2 4.9 0.6 0.4 1.1 0.8 6.5 1.4 0.9 4.2 2.1 0.0 0.0 0.0 0.6 0.4 0.9 2.5 0.1 5.0 0.0 0.5 1.1 5.4 0.1 2.0 2.3 3.4 0.0 0.1 1.2 1.2 0.5 1.2 1.3 0.0 4.5 1.9 1.1 0.0 3.5 0.0 0.0 0.0 2.6 7.0 0.3 2.3 0.0 0.3 0.0 1.1 0.0 5.5 0.0 0.7 0.3 2.4 9.0 0.0 3.6 4.5 2.2 6.2 1.3 3.0 11.0 4.8 0.1 1.7 9.1 2.1 0.0 4.2 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 6.0 5.4 7.0 4.9 6.1 5.7 5.5 6.1 5.5 6.0 6.5 0.6 0.0 1.5 2.6 0.5 0.9 0.3 0.3 1.8 6.8 2.8 2.0 0.7 0.0 1.6 1.8 4.2 1.9 0.0 0.0 1.9 2.3 0.3 0.5 2.2 2.0 0.0 0.0 3.0 0.7 0.4 2.5 0.0 0.5 0.0 1.5 0.0 0.0 0.3 5.0 3.8 0.3 2.0 0.0 0.4 0.1 0.9 0.1 3.6 0.0 0.0 3.3 0.0 8.0 13.5 0.6 0.0 1.9 0.0 0.9 0.0 2.1 2.3 3.1 0.0 1.7 0.8 1.9 6.2 1.5 1.4 0.3 0.1 1.8 0.1 0.1 TRAP1 "HSP75, HSP90L" ENSG00000126602 "TNF receptor associated protein 1" Q12931 16 3651639-3717553 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 140.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041082, HPA044227" Enhanced Enhanced Mitochondria NA NA 1700000 "Cluster 27: Non-specific - Gene expression" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA041082: AB_2677291, HPA044227: AB_2678864" "unprognostic (1.18e-1)" "unprognostic (1.51e-1)" "prognostic favorable (1.80e-4)" "unprognostic (7.10e-2)" "unprognostic (6.80e-2)" "unprognostic (2.76e-2)" "unprognostic (1.52e-2)" "unprognostic (9.61e-2)" "unprognostic (8.58e-2)" "unprognostic (5.71e-3)" "unprognostic (1.54e-1)" "unprognostic (7.69e-3)" "unprognostic (1.01e-2)" "unprognostic (2.24e-2)" "unprognostic (6.68e-2)" "unprognostic (9.90e-2)" "unprognostic (3.82e-2)" 46.4 50.6 32.5 32.7 35.6 35.6 45.7 28.9 37.6 54.0 22.7 50.0 39.7 42.5 18.5 72.2 59.0 33.3 88.1 34.5 34.2 59.9 121.5 33.3 47.6 33.1 32.2 58.8 76.2 39.9 35.3 33.3 33.5 41.6 36.9 22.3 46.1 26.5 193.9 67.7 36.7 30.3 26.8 39.9 49.5 40.1 36.7 27.5 33.3 138.9 36.4 48.9 50.4 32.5 113.4 277.6 56.7 150.2 61.1 62.1 167.6 67.6 60.7 152.2 95.3 347.9 156.5 361.1 123.7 65.1 41.1 207.3 223.0 167.7 67.1 139.3 241.8 105.9 225.1 246.0 105.3 192.0 69.4 74.2 114.6 121.1 188.2 55.0 106.1 122.5 338.4 120.8 50.5 367.8 138.6 141.5 106.0 133.8 140.1 314.1 118.9 500.6 112.8 83.0 268.4 102.2 70.0 254.5 135.8 46.5 184.5 137.2 60.2 63.7 112.9 112.5 99.5 135.5 161.1 289.2 39.7 152.1 88.8 0.1 24.0 0.8 24.7 38.9 47.3 42.1 36.0 31.5 54.9 30.7 42.1 35.9 2.6 31.9 29.8 8.4 33.4 33.0 32.5 35.6 28.9 37.6 34.5 34.2 33.1 32.2 33.5 26.8 36.7 32.5 20.4 22.4 17.5 16.3 21.3 25.4 44.3 63.2 38.1 29.3 32.4 36.8 2.1 45.8 39.8 31.3 10.4 112.6 5.9 28.7 88.0 67.7 24.1 30.6 21.1 21.3 35.5 42.1 31.6 53.8 56.2 23.7 36.2 28.1 16.5 41.5 12.8 48.8 46.1 47.1 31.1 37.5 59.0 14.5 14.8 13.0 16.4 14.7 12.4 12.2 26.3 20.2 12.3 11.6 16.2 31.9 14.5 21.4 37.9 45.9 14.1 140.9 30.1 22.2 19.7 29.9 29.4 37.2 70.9 70.7 28.1 67.2 15.1 58.9 74.9 42.8 TRIM3 "BERP, HAC1, RNF22, RNF97" ENSG00000110171 "Tripartite motif containing 3" O75382 11 6448613-6474459 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 28.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SK-BR-3: 54.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043396, HPA048233" Enhanced Approved Mitochondria NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 45: Enterocytes - Digestion" Mitochondria "HPA043396: AB_2678460, HPA048233: AB_2680321" "unprognostic (1.24e-1)" "unprognostic (1.98e-1)" "unprognostic (2.31e-1)" "prognostic favorable (2.20e-4)" "unprognostic (4.01e-2)" "unprognostic (3.88e-2)" "unprognostic (1.61e-3)" "unprognostic (2.84e-1)" "unprognostic (2.24e-1)" "unprognostic (3.91e-1)" "prognostic favorable (5.49e-5)" "unprognostic (2.01e-1)" "prognostic unfavorable (1.07e-5)" "unprognostic (2.51e-1)" "unprognostic (1.66e-1)" "unprognostic (1.54e-1)" "unprognostic (1.93e-1)" 9.5 4.6 6.4 4.6 6.2 1.3 10.3 11.6 7.5 11.2 0.0 13.0 17.8 13.5 1.8 4.8 10.1 4.1 8.0 5.8 3.4 6.3 6.3 9.7 2.4 8.5 3.1 8.7 6.4 2.7 5.9 3.9 9.4 9.5 4.8 4.8 9.0 5.4 11.5 8.4 15.7 5.6 2.2 5.7 10.1 3.8 5.9 1.5 6.8 4.8 1.6 11.2 9.3 6.1 7.2 12.4 4.9 8.3 8.1 7.8 6.7 10.3 6.1 7.8 8.6 7.6 5.0 3.9 3.6 7.9 9.1 5.0 5.1 7.7 3.0 4.8 7.6 1.2 13.5 5.3 5.2 0.4 4.1 6.7 3.7 6.1 3.2 3.3 8.0 2.9 1.7 4.7 7.8 15.2 0.3 1.0 3.5 15.2 10.7 2.4 4.2 4.9 1.9 3.8 5.1 7.8 5.7 54.9 6.6 2.5 20.8 1.3 13.4 20.3 9.5 15.0 6.9 5.5 3.6 0.8 11.0 1.7 7.6 0.0 1.0 0.6 0.5 1.0 0.4 0.1 0.4 0.4 1.2 0.1 0.1 0.6 0.0 0.6 0.2 0.2 0.5 0.5 6.4 6.2 11.6 7.5 5.8 3.4 8.5 3.1 9.4 2.2 5.9 6.1 8.5 6.4 0.0 9.8 2.4 4.8 2.8 2.8 3.4 8.8 8.5 6.0 2.2 2.8 2.7 0.0 10.4 1.8 3.5 16.0 0.0 3.1 3.9 2.8 4.4 6.5 4.8 0.4 13.2 3.5 2.2 6.9 5.6 7.3 1.3 3.6 4.6 2.5 4.7 8.4 12.2 11.4 4.1 0.8 6.5 5.6 5.9 3.5 7.2 11.2 3.4 2.2 3.1 5.0 10.2 3.1 5.4 5.3 2.5 3.2 28.7 3.1 8.4 9.6 13.1 5.0 11.3 3.1 6.0 3.7 5.4 0.8 3.4 3.3 6.6 2.3 TRIT1 "FLJ20061, IPT" ENSG00000043514 "TRNA isopentenyltransferase 1" Q9H3H1 1 39838110-39883511 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "tRNA processing" Transferase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024174, HPA027330" Approved Supported Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 35: Non-specific - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA024174: AB_1858346, HPA027330: " "unprognostic (4.61e-2)" "unprognostic (1.77e-1)" "unprognostic (8.38e-3)" "prognostic unfavorable (8.80e-4)" "unprognostic (4.00e-2)" "unprognostic (8.55e-2)" "prognostic unfavorable (5.34e-6)" "unprognostic (2.90e-1)" "unprognostic (2.21e-3)" "unprognostic (3.18e-2)" "unprognostic (3.54e-1)" "unprognostic (6.68e-3)" "prognostic unfavorable (7.08e-8)" "unprognostic (6.03e-2)" "unprognostic (1.11e-1)" "unprognostic (1.22e-1)" "unprognostic (6.90e-2)" 9.0 9.9 13.1 7.0 13.1 5.6 12.9 14.7 16.1 15.6 12.8 13.6 6.3 14.7 15.3 18.5 13.1 6.0 15.2 13.1 14.0 15.3 13.0 9.2 8.4 12.1 12.1 14.3 21.5 9.7 16.7 11.8 12.6 19.9 10.5 14.7 13.6 10.9 9.5 21.6 11.1 10.0 12.0 12.6 12.0 11.9 13.9 11.8 16.8 4.4 9.9 15.3 16.8 14.3 20.5 9.4 23.0 18.4 10.6 16.5 29.8 11.1 17.3 22.0 21.8 20.0 20.6 11.5 17.4 11.3 12.2 18.9 29.4 22.7 29.7 17.0 15.6 25.6 22.8 13.5 21.8 21.0 14.4 13.3 21.3 25.0 26.9 25.9 18.0 27.1 31.7 14.1 13.8 11.5 14.3 30.7 31.6 17.4 6.2 21.1 21.6 23.3 21.1 27.3 21.9 16.6 15.2 10.3 17.7 23.0 12.5 37.5 11.0 12.8 18.2 21.1 21.3 19.4 13.2 22.5 14.2 24.6 12.1 0.0 5.4 0.6 2.0 3.9 3.7 2.9 1.8 2.2 10.4 2.2 1.9 2.7 0.2 2.0 5.3 10.1 2.3 2.4 13.1 13.1 14.7 16.1 13.1 14.0 12.1 12.1 12.6 12.0 13.9 14.3 4.9 22.4 7.8 16.6 8.0 14.8 17.1 14.4 10.2 4.6 7.8 9.1 10.8 5.7 11.7 7.3 2.1 34.1 10.3 2.9 7.9 12.2 5.9 13.5 10.8 6.2 10.2 13.3 31.3 9.3 32.8 9.6 3.1 6.1 2.5 9.4 8.9 7.0 8.2 15.2 26.6 8.8 16.2 5.9 5.1 3.1 9.6 7.3 5.4 26.2 12.3 4.9 3.1 34.7 31.3 9.5 5.8 11.3 3.3 8.8 4.5 9.2 25.7 7.3 0.0 8.8 6.9 24.9 16.2 13.2 17.0 16.6 6.1 10.7 9.0 11.2 TRMT61A "C14orf172, FLJ40452, GCD14, Gcd14p, hTRM61" ENSG00000166166 "TRNA methyltransferase 61A" Q96FX7 14 103529196-103537073 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 62.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 10.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024269 Approved Mitochondria NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 43: Cardiomyocytes - Nuclear processes" Mitochondria "HPA024269: " "unprognostic (5.12e-2)" "unprognostic (2.73e-2)" "unprognostic (1.36e-1)" "unprognostic (5.59e-3)" "unprognostic (1.49e-1)" "unprognostic (3.70e-2)" "prognostic unfavorable (1.60e-4)" "unprognostic (1.94e-1)" "unprognostic (3.29e-1)" "unprognostic (2.20e-1)" "unprognostic (3.70e-2)" "unprognostic (9.86e-3)" "unprognostic (2.88e-3)" "unprognostic (4.16e-1)" "unprognostic (2.79e-1)" "unprognostic (1.42e-1)" "unprognostic (1.28e-1)" 10.5 10.0 11.2 4.5 13.6 4.5 9.6 11.2 14.4 15.2 8.1 24.3 4.4 18.7 2.3 9.7 18.9 2.4 7.5 10.9 10.0 13.9 11.6 8.1 3.7 11.9 11.6 10.8 11.0 3.0 7.5 2.7 11.0 17.1 1.7 1.5 7.4 7.0 9.9 10.8 9.6 4.3 10.7 7.6 12.4 8.3 11.7 2.3 15.3 2.6 1.8 21.3 11.2 12.8 10.0 24.4 3.7 7.6 3.8 3.9 15.1 10.8 4.8 13.3 7.2 33.4 16.8 16.1 13.3 5.7 7.8 25.2 8.0 8.3 3.7 11.0 15.0 12.3 9.6 18.0 6.7 15.9 9.2 4.4 10.4 11.6 4.7 3.1 2.3 11.4 18.5 7.6 4.5 28.9 19.6 12.2 12.9 20.7 48.8 24.0 11.6 13.9 5.4 14.5 19.4 12.2 12.4 11.5 14.7 1.4 21.5 9.3 4.6 12.0 12.8 31.9 22.4 10.2 7.0 20.2 12.8 12.7 23.3 0.0 2.1 0.3 2.6 5.4 1.9 2.5 2.1 2.8 3.3 2.6 2.3 2.3 0.0 2.7 10.8 2.2 1.6 2.2 11.2 13.6 11.2 14.4 10.9 10.0 11.9 11.6 11.0 10.7 11.7 12.8 9.8 0.0 6.0 4.9 11.0 26.1 19.9 7.7 6.8 13.7 11.5 13.5 62.7 7.2 4.7 7.3 4.2 13.0 7.2 19.2 17.6 19.4 4.0 6.0 15.7 10.6 10.7 2.5 4.1 12.2 15.5 13.6 8.2 7.2 2.5 12.6 3.9 9.9 12.3 30.3 3.2 10.4 4.1 7.8 7.8 18.9 11.1 6.6 10.6 2.8 12.8 9.4 4.1 0.5 4.8 19.7 9.3 18.4 6.3 22.8 6.3 15.7 5.0 11.2 0.0 12.5 15.4 6.9 12.5 8.5 30.0 12.0 7.0 10.7 19.4 13.6 TRMU "FLJ10140, MTO2, MTU1, TRMT" ENSG00000100416 "TRNA mitochondrial 2-thiouridylase" O75648 22 46330875-46357340 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "RNA-binding, Transferase, tRNA-binding" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000824, HPA035273, HPA043300" Uncertain Supported Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Mitochondria "HPA000824: AB_2732393, HPA035273: AB_10602901, HPA043300: AB_2678415" "unprognostic (2.96e-1)" "unprognostic (1.09e-2)" "unprognostic (8.07e-2)" "unprognostic (4.27e-2)" "unprognostic (2.64e-1)" "unprognostic (3.52e-3)" "prognostic unfavorable (3.04e-5)" "unprognostic (4.72e-2)" "unprognostic (7.14e-2)" "unprognostic (7.89e-2)" "prognostic favorable (6.86e-4)" "unprognostic (4.74e-3)" "prognostic unfavorable (5.63e-6)" "unprognostic (7.26e-2)" "unprognostic (1.73e-1)" "unprognostic (3.56e-1)" "unprognostic (7.44e-3)" 4.2 7.5 7.7 2.3 7.8 2.9 4.0 8.3 9.6 4.3 8.3 4.5 4.7 3.6 7.5 5.6 3.4 2.6 11.2 7.6 8.5 9.1 8.8 3.5 5.0 8.5 8.6 4.0 10.2 8.0 5.3 4.1 8.5 4.4 4.1 2.8 5.5 4.7 6.9 4.8 4.0 3.9 7.9 4.2 4.3 2.3 8.5 3.0 4.6 8.4 4.3 4.2 4.1 7.8 17.8 16.0 6.6 15.1 12.2 8.6 16.6 18.1 12.6 24.9 19.2 22.7 4.5 11.5 12.5 16.2 10.9 15.3 28.5 16.0 21.1 7.5 38.4 13.6 25.0 27.1 10.4 26.5 9.0 8.2 17.6 25.8 8.1 10.3 16.2 5.8 19.3 2.7 15.3 19.1 10.4 21.5 25.5 10.6 27.5 12.2 14.4 21.2 12.5 12.1 15.9 19.0 16.0 18.5 31.7 8.2 10.7 10.9 11.9 11.1 19.8 15.8 20.7 6.5 7.8 12.6 15.7 19.1 22.8 0.0 6.2 3.8 9.4 9.0 8.3 5.4 8.2 8.9 7.1 5.5 7.3 6.9 1.3 8.0 9.8 5.8 11.0 5.9 7.7 7.8 8.3 9.6 7.6 8.5 8.5 8.6 8.5 7.9 8.5 7.8 12.7 9.6 6.1 22.9 13.2 6.2 10.8 16.8 7.4 26.4 10.6 11.8 14.7 10.0 10.7 11.0 16.7 24.9 16.1 14.1 27.4 20.1 1.6 6.3 10.2 14.5 12.5 14.3 19.4 19.6 21.0 11.9 21.9 6.6 9.5 26.8 13.9 16.8 15.9 13.5 18.0 12.3 10.2 9.9 4.0 3.3 15.2 8.8 8.8 5.6 14.9 11.9 20.6 10.1 14.6 19.5 9.9 17.0 13.8 14.2 15.3 27.9 10.2 26.4 6.6 7.6 14.4 18.5 12.9 9.6 9.7 15.3 13.1 21.0 19.3 9.9 TRNT1 "CCA1, CGI-47, MtCCA" ENSG00000072756 "TRNA nucleotidyl transferase 1" Q96Q11 3 3126933-3150879 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Nucleotidyltransferase, RNA-binding, Transferase" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036938 Uncertain Supported Mitochondria Yes No "Cluster 46: Basophils - DNA binding" "Cluster 7: Kidney - Transmembrane transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA036938: AB_10670566" "unprognostic (6.39e-3)" "unprognostic (1.58e-1)" "unprognostic (2.38e-3)" "unprognostic (4.69e-2)" "unprognostic (4.92e-2)" "unprognostic (2.41e-1)" "unprognostic (1.39e-2)" "unprognostic (2.68e-1)" "unprognostic (6.22e-2)" "unprognostic (5.65e-2)" "unprognostic (4.62e-2)" "unprognostic (1.41e-2)" "unprognostic (1.24e-2)" "unprognostic (6.50e-2)" "unprognostic (1.09e-1)" "unprognostic (3.78e-1)" "unprognostic (1.02e-1)" 9.7 10.0 7.2 8.9 7.2 3.5 8.5 7.9 8.0 7.8 7.0 8.1 4.4 8.8 5.5 9.4 7.6 8.3 8.4 7.4 7.2 17.2 10.0 8.4 9.7 7.1 7.3 8.3 8.4 8.3 10.3 10.5 7.1 11.3 7.6 4.0 7.7 6.3 9.3 6.4 7.9 8.3 7.3 10.7 9.1 6.5 7.4 9.8 11.3 7.6 10.9 13.1 7.9 8.0 20.0 29.6 18.2 9.8 24.1 21.5 20.5 19.9 17.4 21.6 20.9 25.0 20.9 35.6 12.8 22.4 32.0 12.6 24.6 18.6 26.5 24.6 13.3 28.7 25.3 24.9 31.4 32.2 20.8 17.9 25.0 20.2 6.8 15.0 21.0 24.1 25.1 9.8 35.9 37.2 22.0 21.4 15.2 29.2 19.0 20.5 28.1 32.5 26.1 25.8 10.8 15.9 31.6 20.6 18.5 26.3 18.7 16.3 14.8 22.8 18.7 23.6 25.7 12.6 31.4 43.4 17.2 27.6 25.0 49.4 12.4 36.4 16.4 18.1 16.0 25.8 20.8 18.1 16.8 15.7 22.7 20.1 16.6 19.8 19.0 15.6 18.6 11.2 7.2 7.2 7.9 8.0 7.4 7.2 7.1 7.3 7.1 7.3 7.4 8.0 20.7 16.0 13.4 15.3 30.2 14.8 29.0 19.9 24.5 13.5 12.1 11.0 14.3 2.8 16.3 18.4 14.6 25.8 23.5 10.6 45.0 19.1 2.3 15.8 19.0 21.1 8.4 16.6 23.8 9.9 17.8 19.9 23.4 12.0 22.8 20.7 12.5 9.2 13.3 10.1 27.0 10.7 16.2 11.0 13.3 2.9 10.8 13.3 7.2 23.4 20.3 17.1 18.6 23.6 34.7 10.6 9.2 8.6 30.7 30.9 11.0 32.7 11.4 15.7 0.0 14.9 17.4 20.8 17.9 23.4 13.1 28.3 22.0 24.7 13.5 23.9 TRPT1 MGC11134 ENSG00000149743 "TRNA phosphotransferase 1" Q86TN4 11 64223799-64226254 "Enzymes, Predicted intracellular proteins" "tRNA processing" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 173.8" "Cell type enhanced" "Detected in many" "Early spermatids: 147.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038705, HPA038706" Uncertain Approved Mitochondria NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 27: Mucus-secreting cells - Mucin production" Mitochondria "HPA038705: AB_2676161, HPA038706: AB_10671863" "unprognostic (2.50e-2)" "unprognostic (1.72e-1)" "unprognostic (1.33e-1)" "unprognostic (3.59e-2)" "unprognostic (7.20e-2)" "unprognostic (1.53e-1)" "unprognostic (5.84e-2)" "unprognostic (8.56e-2)" "unprognostic (1.18e-1)" "unprognostic (3.26e-3)" "unprognostic (1.12e-1)" "unprognostic (7.71e-2)" "unprognostic (7.38e-2)" "unprognostic (2.49e-1)" "unprognostic (3.28e-1)" "unprognostic (1.99e-1)" "unprognostic (4.58e-3)" 27.6 38.8 33.1 14.1 34.9 8.4 27.5 36.3 36.2 26.3 33.8 35.2 22.2 23.1 21.4 35.2 26.3 15.4 88.3 31.7 34.6 52.0 46.5 20.3 16.3 35.0 34.0 26.0 51.3 19.2 35.2 10.9 33.7 36.0 18.4 12.7 38.9 28.4 173.8 27.4 30.3 12.0 34.1 30.8 41.9 51.1 36.7 21.1 33.5 116.1 17.6 30.0 25.8 34.3 25.1 24.5 26.5 43.0 32.0 23.5 32.2 16.4 31.6 28.7 24.0 16.1 37.1 24.7 63.6 27.4 22.2 34.1 11.8 35.7 10.1 23.8 14.2 12.7 23.8 28.0 46.4 16.2 21.4 17.7 20.7 31.6 28.1 52.7 20.4 49.0 22.3 27.1 24.2 59.4 30.3 33.7 16.8 33.3 26.1 39.3 19.5 71.4 74.4 29.1 23.0 33.4 13.2 32.1 47.5 18.0 37.1 25.8 23.9 19.4 14.9 37.9 16.4 53.0 14.3 16.3 46.7 8.3 32.1 11.0 16.9 28.5 18.8 31.2 15.0 38.0 18.5 19.9 24.4 39.9 20.1 23.3 15.8 26.1 27.4 59.0 25.2 12.0 33.1 34.9 36.3 36.2 31.7 34.6 35.0 34.0 33.7 34.1 36.7 34.3 17.1 9.6 23.1 9.8 31.4 13.3 18.7 32.7 28.5 8.9 40.4 45.3 42.5 32.9 25.5 27.6 0.0 44.4 17.0 66.3 95.9 41.4 147.5 41.3 20.1 17.5 26.9 14.9 2.8 58.4 46.7 19.8 41.8 27.5 24.6 10.0 21.0 30.0 25.5 10.1 4.9 111.3 30.5 18.9 12.8 82.1 19.9 15.0 37.4 2.8 27.2 32.1 15.5 7.5 6.8 46.6 60.5 17.0 47.1 24.0 92.0 82.9 48.2 11.6 6.6 22.4 29.3 59.6 13.4 42.8 18.5 36.0 21.8 20.2 40.3 22.6 TST RDS ENSG00000128311 "Thiosulfate sulfurtransferase" Q16762 22 37010859-37020183 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 561.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 565.8;Hepatocytes: 414.9;Paneth cells: 463.4;Proximal enterocytes: 278.5;Proximal tubular cells: 254.5;Undifferentiated cells: 217.4" "Cancer enhanced" "Detected in all" "liver cancer: 177.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 25.0" "Group enriched" "Detected in all" 6 "dendritic cells: 25.0;granulocytes: 21.8;monocytes: 17.7" "Cell line enhanced" "Detected in many" "OE19: 264.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003044, HPA003643, CAB009546" Enhanced Supported Mitochondria NA NA 560000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "CAB009546: AB_2211220, HPA003044: AB_1858417, HPA003643: AB_1080411" "unprognostic (3.09e-2)" "unprognostic (2.70e-1)" "unprognostic (2.07e-1)" "unprognostic (1.21e-2)" "unprognostic (2.36e-2)" "unprognostic (1.11e-1)" "unprognostic (2.49e-2)" "unprognostic (2.38e-2)" "unprognostic (2.32e-1)" "unprognostic (7.96e-3)" "unprognostic (4.38e-2)" "unprognostic (1.78e-1)" "prognostic favorable (7.59e-6)" "unprognostic (6.08e-3)" "unprognostic (3.46e-1)" "unprognostic (1.16e-1)" "prognostic favorable (1.04e-4)" 51.4 154.1 31.3 20.9 40.5 27.1 37.3 38.2 36.0 34.1 31.3 190.7 147.7 18.9 2.9 96.7 25.7 75.9 69.9 29.1 33.1 100.8 561.2 22.7 8.1 34.4 35.2 26.9 63.6 9.4 12.4 7.9 34.4 26.4 80.3 1.3 39.8 18.2 52.9 33.8 114.2 13.2 35.4 16.9 88.4 8.1 35.8 4.3 17.1 34.9 16.2 30.0 56.7 39.0 42.6 86.1 10.8 36.8 25.9 10.6 21.4 23.0 18.6 12.6 18.3 25.4 25.7 11.1 18.8 17.0 11.9 35.1 7.9 22.3 2.7 33.6 50.0 11.5 15.5 49.7 64.9 16.4 26.4 20.1 23.9 9.1 7.6 17.5 31.1 5.9 14.2 18.2 6.0 90.8 0.5 49.9 18.7 264.4 39.3 37.0 11.7 19.7 35.9 36.7 6.4 17.1 24.2 41.4 31.7 10.2 43.4 39.3 25.1 14.0 27.2 24.2 7.4 14.0 15.4 3.4 5.3 46.4 8.5 10.9 17.7 8.0 0.8 4.7 1.7 2.8 0.8 0.6 25.0 1.7 0.4 0.2 21.8 3.7 1.5 1.7 2.1 8.1 31.3 40.5 38.2 36.0 29.1 33.1 34.4 35.2 34.4 35.4 35.8 39.0 13.9 28.9 74.8 10.1 7.8 1.3 9.5 20.4 12.0 1.3 32.7 16.6 39.2 170.1 23.7 20.2 0.0 11.6 2.5 565.8 46.9 45.3 1.9 53.3 30.2 13.4 34.3 35.3 0.3 44.0 6.4 14.6 126.9 74.3 14.0 60.9 39.3 414.9 15.1 1.7 0.5 162.8 8.2 28.9 6.8 3.5 13.1 23.2 1.8 1.0 18.6 27.3 3.1 3.5 7.4 36.8 463.4 7.9 24.5 10.5 278.5 254.5 19.2 0.8 0.0 10.7 11.5 2.4 0.5 39.8 2.4 11.4 5.0 57.5 217.4 17.3 TTC19 "FLJ20343, MGC19520" ENSG00000011295 "Tetratricopeptide repeat domain 19" Q6DKK2 17 15999784-16045015 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Electron transport, Respiratory chain, Transport" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 5.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023010, HPA052380" Enhanced Enhanced Mitochondria "Intracellular and membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 52: Non-specific - Transcription" Mitochondria "HPA023010: AB_1858429, HPA052380: AB_2681806" "unprognostic (1.04e-2)" "unprognostic (4.90e-3)" "unprognostic (2.87e-2)" "unprognostic (4.80e-3)" "unprognostic (8.09e-2)" "unprognostic (2.86e-1)" "unprognostic (1.06e-2)" "unprognostic (2.84e-2)" "unprognostic (8.34e-2)" "unprognostic (1.72e-2)" "unprognostic (2.30e-3)" "unprognostic (5.14e-2)" "prognostic favorable (5.67e-4)" "unprognostic (1.31e-1)" "unprognostic (3.22e-1)" "unprognostic (4.85e-2)" "unprognostic (2.24e-1)" 6.6 11.4 8.1 3.8 7.8 11.2 7.5 19.4 11.6 6.9 8.4 8.0 10.3 6.9 5.2 6.8 5.8 5.2 8.6 8.8 9.6 8.7 7.7 6.6 4.6 7.9 7.4 6.9 12.4 11.2 8.0 5.8 7.9 6.8 5.7 9.9 9.1 4.2 8.8 9.5 9.8 3.8 6.3 4.5 8.4 3.6 8.0 3.9 10.6 4.4 3.3 6.3 6.7 10.5 7.0 4.1 7.6 12.1 6.4 5.6 4.0 3.1 4.6 3.1 3.8 6.5 12.8 8.9 9.8 4.3 4.6 9.1 9.9 8.3 3.8 12.5 10.2 8.2 9.2 6.3 9.1 9.3 11.6 5.6 7.0 2.6 11.4 9.6 7.1 12.4 4.6 7.7 6.8 7.6 7.5 6.8 10.0 11.8 3.0 7.8 8.0 8.2 11.6 10.5 6.6 5.5 7.6 9.8 16.6 24.6 6.9 4.6 13.1 4.2 1.2 6.1 7.5 4.8 1.5 4.2 9.8 9.8 9.5 5.2 0.7 1.8 0.7 0.7 1.2 0.9 0.9 1.2 0.7 1.1 1.0 1.3 0.7 0.6 0.7 1.1 1.0 0.4 8.1 7.8 19.4 11.6 8.8 9.6 7.9 7.4 7.9 6.3 8.0 10.5 51.0 41.7 38.6 69.5 60.8 105.3 83.5 30.8 70.6 147.8 65.1 47.9 34.8 42.9 35.4 46.0 143.9 75.7 62.8 59.7 70.5 50.0 59.4 49.4 41.5 60.3 45.6 32.4 115.1 41.2 41.9 34.2 43.8 67.9 31.1 46.8 42.8 36.0 25.6 129.5 100.9 52.3 26.4 25.8 76.7 7.2 41.0 46.5 55.2 35.6 34.8 73.9 70.0 54.3 57.8 47.7 57.9 33.4 34.5 89.1 75.4 47.1 26.5 180.4 46.0 56.5 40.2 30.2 31.1 56.9 116.8 65.5 68.9 69.9 63.3 72.7 TTLL4 KIAA0173 ENSG00000135912 "Tubulin tyrosine ligase like 4" Q14679 2 218710835-218755416 "Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 39.4;Muller glia cells: 72.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027091, HPA050252" Approved Approved Mitochondria NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 39: CACO-2 - Unknown function" "Cluster 5: Muller glia cells - Visual perception" Mitochondria "HPA027091: AB_10601828, HPA050252: AB_2681064" "unprognostic (1.76e-1)" "unprognostic (1.91e-1)" "unprognostic (4.64e-1)" "unprognostic (1.49e-2)" "unprognostic (2.09e-1)" "unprognostic (1.66e-2)" "prognostic unfavorable (2.95e-5)" "unprognostic (3.83e-3)" "unprognostic (2.96e-2)" "unprognostic (1.21e-1)" "unprognostic (7.52e-2)" "unprognostic (2.42e-2)" "prognostic unfavorable (6.63e-12)" "unprognostic (9.84e-2)" "unprognostic (1.09e-1)" "unprognostic (1.85e-1)" "unprognostic (5.29e-3)" 3.9 7.2 7.1 8.4 9.9 5.8 6.4 7.5 9.6 5.4 20.1 5.5 5.6 4.7 3.5 6.9 7.3 4.2 4.6 7.2 8.4 4.4 5.9 6.9 6.2 9.7 11.2 4.5 7.1 5.2 6.7 8.0 10.1 6.6 6.4 15.2 6.8 3.7 5.6 8.6 5.8 5.2 7.2 5.7 8.9 25.5 9.6 5.7 3.9 2.9 8.9 5.2 6.3 10.6 18.4 12.3 32.3 16.4 8.1 6.3 43.5 12.2 9.8 19.8 16.8 52.6 21.4 14.4 10.1 9.5 18.9 19.0 34.3 16.9 23.0 16.3 27.3 18.5 19.0 50.2 11.5 23.6 13.1 10.4 10.1 17.7 19.9 8.5 19.0 16.0 53.8 22.2 11.0 10.7 13.1 15.3 36.4 13.5 8.1 29.4 14.6 18.9 19.7 14.5 12.9 12.7 9.3 13.7 23.9 48.9 11.1 12.0 7.6 17.6 17.9 11.3 11.7 11.2 10.1 32.4 9.2 14.5 23.4 0.1 12.6 0.8 3.1 6.0 2.9 3.9 2.3 2.3 7.3 3.5 1.5 1.4 14.5 2.1 8.8 4.3 1.3 5.1 7.1 9.9 7.5 9.6 7.2 8.4 9.7 11.2 10.1 7.2 9.6 10.6 1.6 3.2 5.8 28.4 3.1 4.6 12.3 3.2 4.6 6.6 4.5 5.1 3.5 5.7 4.2 7.3 27.1 6.8 3.0 2.4 0.0 6.0 39.4 7.8 3.1 3.7 5.4 6.5 3.9 3.9 8.0 4.8 10.2 5.3 1.3 4.2 1.8 2.6 7.8 3.3 4.8 4.7 4.1 5.5 2.9 16.1 3.1 9.4 3.6 15.9 10.4 72.7 5.2 11.1 20.8 5.8 2.5 1.5 2.8 15.2 2.9 1.8 7.5 12.7 0.0 3.3 3.1 18.3 12.7 4.2 4.1 5.7 2.5 2.1 5.1 11.4 TUFM "EF-TuMT, EFTu" ENSG00000178952 "Tu translation elongation factor, mitochondrial" P49411 16 28842411-28846348 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Elongation factor" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018991, HPA024087, CAB075730, CAB075731, CAB075732" Enhanced Enhanced Mitochondria NA NA 610000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB075730: AB_2665736, CAB075731: AB_2665737, CAB075732: AB_2665738, HPA018991: AB_1858458, HPA024087: AB_1858459" "unprognostic (1.40e-1)" "unprognostic (7.56e-2)" "unprognostic (1.29e-1)" "unprognostic (1.73e-2)" "unprognostic (2.36e-1)" "unprognostic (2.55e-2)" "unprognostic (3.39e-1)" "unprognostic (1.23e-3)" "unprognostic (8.05e-2)" "unprognostic (8.47e-2)" "unprognostic (1.80e-1)" "unprognostic (1.33e-1)" "prognostic favorable (2.69e-6)" "unprognostic (5.26e-2)" "unprognostic (1.09e-1)" "unprognostic (6.22e-2)" "unprognostic (7.36e-2)" 69.7 114.6 69.6 67.1 74.2 75.1 65.8 78.9 78.1 59.4 93.3 101.5 104.4 64.9 34.7 105.2 73.6 46.6 177.8 68.1 75.3 107.3 145.1 58.3 69.2 73.1 77.4 61.4 114.2 117.1 55.4 47.6 74.1 57.7 86.1 35.8 88.9 59.7 224.4 76.0 83.9 53.6 72.9 66.2 106.1 73.3 77.0 59.9 62.7 221.5 79.3 67.1 62.9 74.3 176.2 323.1 102.4 216.2 144.9 131.4 208.7 125.8 144.4 194.9 183.0 351.3 189.4 390.5 228.5 126.4 112.4 337.6 244.2 242.9 116.2 155.4 370.8 151.7 254.8 433.6 171.7 273.8 134.8 169.9 188.1 211.9 208.7 126.8 235.2 213.0 339.0 150.3 144.4 355.0 262.3 266.3 231.8 213.9 196.9 361.8 187.3 569.6 169.3 168.4 178.8 219.6 110.0 388.5 180.2 84.6 231.5 217.6 150.1 115.9 136.4 146.7 196.6 229.8 253.6 172.2 148.6 336.8 157.1 94.6 155.8 72.3 103.1 153.6 115.3 100.6 97.2 108.7 199.3 98.8 91.7 95.3 32.4 97.2 119.2 123.1 140.1 185.6 69.6 74.2 78.9 78.1 68.1 75.3 73.1 77.4 74.1 72.9 77.0 74.3 108.2 70.5 76.7 29.4 144.6 168.1 262.5 322.0 158.2 102.4 165.1 139.2 134.4 190.1 182.6 176.6 87.6 333.1 113.2 260.0 334.6 230.2 381.8 116.1 92.5 111.3 148.5 148.1 17.5 289.8 299.2 111.2 153.4 79.6 105.9 170.6 108.5 247.1 253.8 74.0 19.9 230.5 217.7 167.5 146.4 669.0 109.3 128.6 138.7 14.0 167.5 140.6 88.6 28.6 30.3 199.7 215.3 111.7 264.9 245.3 330.7 451.9 237.3 116.3 85.5 105.5 129.1 205.7 177.4 230.1 156.0 287.0 120.2 288.2 418.7 277.6 TXN2 MT-TRX ENSG00000100348 "Thioredoxin 2" Q99757 22 36467046-36481640 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Transport" "Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000994, CAB008681" Approved Enhanced Mitochondria No No 84000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB008681: AB_1623682, HPA000994: AB_1080267" "unprognostic (5.11e-2)" "unprognostic (4.40e-3)" "unprognostic (4.40e-3)" "unprognostic (1.07e-2)" "unprognostic (5.85e-2)" "unprognostic (4.28e-2)" "unprognostic (4.02e-2)" "unprognostic (5.05e-2)" "unprognostic (2.15e-1)" "unprognostic (1.78e-1)" "unprognostic (3.17e-2)" "prognostic favorable (2.04e-4)" "prognostic favorable (1.17e-6)" "unprognostic (1.49e-2)" "unprognostic (2.78e-1)" "unprognostic (1.06e-1)" "unprognostic (2.05e-1)" 60.3 182.3 89.8 45.5 92.4 64.7 58.0 94.6 98.2 57.4 92.4 65.3 84.0 50.0 51.7 79.8 64.1 49.4 122.3 87.9 90.7 91.5 149.5 44.7 59.2 92.9 91.3 75.8 59.2 99.1 43.4 47.3 91.9 59.3 63.6 43.0 59.5 52.5 159.4 60.5 64.3 48.3 91.2 65.7 76.1 48.8 97.0 50.9 67.7 180.1 59.9 59.0 54.0 91.7 52.8 80.4 75.4 126.8 115.2 125.0 81.3 70.8 108.1 114.8 128.7 87.9 52.1 133.3 64.2 116.8 54.5 76.1 151.7 127.4 66.1 93.6 131.8 147.7 91.7 125.4 94.6 189.6 125.8 162.3 98.9 101.9 79.3 99.5 118.2 78.4 157.7 104.1 106.1 80.3 87.5 128.2 60.0 170.3 95.3 75.3 79.5 92.6 116.4 84.8 99.9 98.3 70.2 148.1 125.3 61.3 103.6 165.9 83.7 120.5 95.0 69.8 65.9 81.4 64.2 128.6 111.0 109.5 74.1 30.2 173.5 32.3 102.5 194.3 108.9 140.4 101.2 109.0 223.4 133.8 116.4 108.6 59.3 145.4 170.1 167.1 110.9 224.3 89.8 92.4 94.6 98.2 87.9 90.7 92.9 91.3 91.9 91.2 97.0 91.7 68.9 60.9 53.0 12.1 66.4 83.5 87.7 154.0 108.1 105.6 124.3 137.7 105.4 88.6 82.5 69.9 39.6 213.2 62.8 128.5 303.3 93.0 19.6 45.7 70.6 73.7 89.5 114.0 8.3 106.2 275.8 74.0 75.4 57.2 69.1 148.0 81.0 122.7 173.4 116.1 10.3 132.4 95.6 100.5 80.7 36.8 56.5 80.7 78.2 8.4 91.9 168.9 77.2 9.0 13.5 82.5 104.3 50.8 79.5 52.7 252.2 213.7 49.0 59.4 19.7 61.1 67.1 49.1 42.4 124.5 89.8 207.1 62.4 287.0 179.6 87.1 TXNDC16 KIAA1344 ENSG00000087301 "Thioredoxin domain containing 16" Q9P2K2 14 52430596-52552522 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 26.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 69.8;Glandular and luminal cells: 124.9;Inhibitory neurons: 88.8" "Cancer enhanced" "Detected in all" "prostate cancer: 18.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002543 Approved Approved Mitochondria "Secreted to blood" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 44: Endometrium - Transcription" Mitochondria "HPA002543: AB_1079199" "unprognostic (1.37e-1)" "unprognostic (7.79e-3)" "unprognostic (5.95e-3)" "unprognostic (2.36e-1)" "unprognostic (5.95e-3)" "unprognostic (9.73e-2)" "unprognostic (2.50e-1)" "unprognostic (1.43e-2)" "unprognostic (7.01e-2)" "unprognostic (1.49e-1)" "unprognostic (2.07e-2)" "unprognostic (1.21e-1)" "prognostic favorable (6.79e-4)" "unprognostic (1.39e-1)" "unprognostic (1.56e-1)" "unprognostic (3.55e-3)" "unprognostic (2.04e-1)" 6.2 4.0 4.6 3.5 4.6 5.1 6.9 10.1 6.0 9.3 0.6 5.8 4.1 6.9 14.6 3.7 4.1 5.2 3.7 4.9 4.3 5.0 7.4 4.4 4.5 3.9 4.0 10.3 6.4 7.0 3.8 5.8 4.3 26.7 5.9 9.1 4.0 13.0 2.0 4.6 4.8 4.3 4.0 10.2 6.3 7.1 4.1 5.9 4.0 4.0 3.9 3.4 3.8 6.7 8.3 0.8 8.9 5.0 6.5 4.7 7.0 2.7 3.6 4.5 8.7 3.0 6.6 13.5 8.9 2.2 2.8 7.7 10.3 3.7 6.9 5.7 13.5 6.2 6.2 2.8 4.7 7.4 2.9 8.8 3.4 5.8 4.2 4.0 5.1 5.8 8.0 20.4 3.9 4.0 9.3 5.1 9.9 5.5 4.9 18.4 16.9 12.4 5.7 8.4 29.0 10.0 13.2 13.5 3.9 7.5 8.6 5.4 2.7 6.0 3.0 6.9 4.6 5.6 8.0 13.5 1.7 7.7 3.5 1.3 3.0 1.2 1.3 2.4 1.3 0.5 1.3 0.9 2.6 0.3 0.6 0.6 1.7 0.6 2.9 1.0 2.4 1.0 4.6 4.6 10.1 6.0 4.9 4.3 3.9 4.0 4.3 4.0 4.1 6.7 9.1 9.6 6.4 23.2 6.1 6.6 6.0 2.5 9.6 42.3 26.6 19.0 10.1 8.6 5.0 7.3 8.4 2.3 15.1 8.8 1.9 5.2 4.0 69.8 9.6 7.4 18.5 21.8 61.0 3.9 1.6 7.2 13.3 124.9 2.5 13.9 15.4 14.1 3.3 10.1 88.8 17.9 0.0 18.8 8.6 4.2 27.7 13.0 1.8 24.4 5.9 7.3 7.2 45.8 51.5 1.3 8.5 52.3 11.3 19.0 5.9 2.8 4.4 44.8 0.0 11.1 11.2 12.0 9.5 8.1 8.4 1.1 7.7 5.7 10.9 4.5 UBE2H "GID3, UBC8, UBCH" ENSG00000186591 "Ubiquitin conjugating enzyme E2 H" P62256 7 129830732-129952960 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 365.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003302 Approved Approved Mitochondria NA NA 21000 "Cluster 24: B-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 44: Endometrium - Transcription" Mitochondria "HPA003302: AB_1858526" "unprognostic (1.15e-1)" "unprognostic (5.85e-2)" "unprognostic (5.67e-3)" "unprognostic (2.76e-1)" "unprognostic (2.25e-1)" "unprognostic (3.08e-2)" "unprognostic (1.13e-1)" "unprognostic (1.37e-1)" "unprognostic (9.43e-2)" "unprognostic (6.19e-2)" "prognostic unfavorable (2.33e-5)" "unprognostic (1.13e-1)" "unprognostic (3.73e-2)" "unprognostic (2.37e-1)" "unprognostic (1.12e-1)" "unprognostic (3.58e-1)" "unprognostic (1.23e-1)" 46.8 64.7 43.0 29.1 44.2 42.3 34.4 46.4 49.1 44.7 58.7 42.3 23.4 44.3 37.6 49.9 44.6 44.6 98.2 42.1 45.4 42.1 44.2 38.8 31.8 48.7 43.4 41.7 84.3 49.2 29.4 52.5 45.0 36.1 26.0 42.0 39.3 41.5 69.3 31.2 24.4 49.2 41.8 28.6 34.6 36.4 45.8 37.4 45.0 60.6 39.8 40.1 33.7 47.8 82.6 43.8 58.5 56.1 126.1 107.5 86.5 72.0 97.8 45.8 51.1 22.9 92.5 34.0 87.4 76.6 123.8 62.5 46.2 81.6 59.5 40.9 22.6 11.5 63.5 28.6 98.3 23.6 36.8 146.7 106.9 61.3 99.7 106.3 89.7 36.3 27.5 104.1 71.5 29.9 31.1 26.1 80.0 60.5 49.8 24.4 27.8 77.2 95.9 106.5 20.3 59.6 68.3 164.7 43.8 166.0 17.1 27.2 89.1 51.7 24.2 72.2 76.5 83.5 65.6 58.5 102.1 28.9 49.7 2.2 1.4 3.4 2.8 1.2 3.8 2.3 2.8 2.6 1.3 4.5 3.6 3.8 4.8 0.9 1.5 2.3 4.4 1.3 43.0 44.2 46.4 49.1 42.1 45.4 48.7 43.4 45.0 41.8 45.8 47.8 69.9 41.7 51.8 87.1 43.1 145.8 187.5 65.7 59.7 65.1 83.7 49.4 102.9 44.3 69.3 71.7 60.5 116.3 56.7 38.6 41.1 66.0 93.5 225.7 91.2 81.4 59.1 100.0 97.1 70.9 67.1 65.2 43.8 365.8 14.7 53.9 45.3 73.1 41.8 43.7 116.9 35.3 54.9 40.3 69.8 44.0 44.1 52.0 48.0 89.0 26.2 87.4 51.5 113.1 108.5 118.3 33.6 78.6 60.5 227.6 27.6 49.7 95.3 35.6 13.1 65.9 69.0 46.5 22.5 78.6 153.7 200.4 49.2 79.7 26.6 274.3 UCP2 "BMIQ4, SLC25A8" ENSG00000175567 "Uncoupling protein 2" P55851 11 73974672-73982843 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 278.1" "Cell type enhanced" "Detected in many" "dendritic cells: 404.4;Enteroendocrine cells: 297.3;Erythroid cells: 695.6;Hofbauer cells: 442.2;Kupffer cells: 326.6;monocytes: 533.6;NK-cells: 509.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 360.2;SK-BR-3: 395.6;U-698: 293.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025583, HPA075202" Approved Supported Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 3: T-cells - Adaptive immune response" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 6: Erythroid cells - Oxygen transport" Mitochondria "CAB025583: , HPA075202: AB_2732284" "unprognostic (1.13e-1)" "prognostic favorable (4.65e-5)" "unprognostic (8.07e-2)" "unprognostic (1.21e-2)" "unprognostic (1.08e-1)" "unprognostic (1.15e-2)" "unprognostic (1.92e-1)" "unprognostic (1.82e-3)" "unprognostic (2.07e-1)" "unprognostic (4.59e-2)" "unprognostic (1.13e-3)" "unprognostic (1.37e-1)" "prognostic unfavorable (7.80e-6)" "unprognostic (3.77e-2)" "unprognostic (1.58e-1)" "unprognostic (3.77e-3)" "unprognostic (3.88e-3)" 70.9 20.5 12.2 142.9 14.6 132.8 37.6 12.9 24.1 41.3 22.1 33.2 53.4 17.4 7.6 17.7 175.7 42.3 14.1 12.1 15.9 34.9 26.2 69.3 278.1 19.7 19.8 4.9 12.6 8.1 13.8 27.3 19.8 19.7 44.8 6.9 42.7 23.0 99.1 9.2 56.6 30.4 17.6 183.1 55.2 14.5 22.4 217.3 45.1 141.7 240.2 73.6 4.9 26.1 0.9 78.7 20.2 43.5 9.5 0.0 11.6 14.1 9.3 54.9 14.8 153.1 59.0 360.2 165.1 19.5 5.5 3.5 13.3 0.0 28.6 97.1 5.6 241.5 26.4 28.3 32.2 123.9 77.5 8.9 0.0 43.9 0.0 11.0 5.7 144.6 101.5 119.0 9.5 147.5 108.5 55.8 12.8 9.0 21.7 99.7 120.7 202.0 150.4 211.0 23.6 32.3 68.2 395.6 26.6 55.9 123.3 79.3 10.0 0.2 59.7 14.4 21.5 48.4 24.4 293.8 7.2 45.0 0.4 809.1 1116.7 1465.3 1462.8 1945.8 925.0 1914.8 1176.3 1233.5 1228.7 1851.8 1092.9 1143.1 154.2 1816.8 1692.3 3009.5 2589.5 2966.6 12.2 14.6 12.9 24.1 12.1 15.9 19.7 19.8 19.8 17.6 22.4 26.1 4.7 3.2 27.6 0.3 287.4 3.4 2.7 20.2 0.6 0.9 30.9 19.8 5.2 5.7 43.9 92.0 8.4 8.3 404.4 6.2 7.9 1.9 18.7 122.1 10.5 8.9 297.3 695.6 0.0 7.5 12.1 9.9 46.4 102.4 86.2 12.4 9.7 5.0 442.2 0.0 0.1 31.5 89.5 326.6 146.2 46.0 0.9 232.3 26.6 1.9 533.6 4.3 509.8 1.0 1.0 1.8 45.9 0.4 117.9 12.8 4.5 2.7 137.6 8.1 6.6 6.1 11.2 15.2 14.5 1.9 4.5 11.2 189.9 13.5 21.7 43.4 UGT8 CGT ENSG00000174607 "UDP glycosyltransferase 8" Q16880 4 114598770-114678225 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 266.4" "Cell type enriched" "Detected in many" 8 "Oligodendrocytes: 821.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "memory B-cell: 6.9;naive B-cell: 10.7" "Lineage enriched" "Detected in single" 12 "B-cells: 10.7" "Cell line enhanced" "Detected in many" "CAPAN-2: 58.4;OE19: 123.7;RPTEC TERT1: 55.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014405, HPA065785" Enhanced Approved Mitochondria No No "Cluster 19: B-cells - Humoral immune response" "Cluster 70: Brain - Nervous system development" "Cluster 21: OE19 - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA014405: AB_1858606, HPA065785: AB_2685559" "unprognostic (7.38e-3)" "unprognostic (2.07e-1)" "unprognostic (1.25e-2)" "unprognostic (2.38e-1)" "unprognostic (1.63e-1)" "unprognostic (1.63e-2)" "unprognostic (1.16e-2)" "unprognostic (2.38e-1)" "unprognostic (7.78e-2)" "unprognostic (1.56e-3)" "unprognostic (4.49e-2)" "unprognostic (2.76e-1)" "prognostic favorable (8.55e-5)" "unprognostic (2.80e-1)" "unprognostic (1.78e-2)" "unprognostic (7.53e-2)" "unprognostic (1.49e-1)" 0.6 0.6 58.6 4.6 153.7 1.1 4.6 166.2 94.5 7.0 9.7 26.8 30.3 3.8 0.3 1.5 4.4 11.0 0.3 66.2 94.7 31.0 0.2 1.1 4.9 220.9 132.8 0.4 8.5 0.2 0.2 0.2 200.6 0.5 27.7 2.2 7.3 0.7 0.5 2.2 27.7 1.6 139.2 1.7 16.8 5.0 132.4 0.6 13.5 0.4 5.0 0.6 0.6 266.4 0.6 0.2 4.4 0.6 0.3 0.0 0.7 0.2 0.0 0.1 3.4 17.7 58.4 17.6 1.2 0.2 13.8 25.8 0.0 0.1 0.1 0.3 14.3 0.3 24.6 0.0 0.0 0.4 0.4 0.0 0.0 0.1 0.0 5.4 0.1 0.2 16.1 3.0 0.1 0.3 0.3 1.7 6.4 123.7 8.8 1.6 28.9 0.3 55.2 0.6 31.4 4.6 0.2 5.4 0.8 1.1 0.9 5.4 1.0 1.1 19.2 0.7 19.6 6.3 0.8 0.6 29.2 0.9 17.9 0.2 0.0 0.8 0.0 0.0 0.6 6.9 0.0 0.0 0.0 10.7 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.3 58.6 153.7 166.2 94.5 66.2 94.7 220.9 132.8 200.6 139.2 132.4 266.4 0.1 6.4 1.5 1.0 22.0 0.0 1.8 0.3 6.8 0.0 5.7 6.1 0.8 8.6 3.9 25.8 0.0 0.0 0.1 19.0 9.8 1.4 9.2 9.6 1.7 0.5 48.4 0.0 1.0 13.1 0.0 0.6 19.4 21.4 0.0 0.2 0.0 0.0 0.0 0.0 3.7 27.9 0.0 0.0 0.0 3.5 1.2 0.5 1.8 2.8 0.0 0.0 0.0 98.5 821.1 10.8 14.6 0.0 4.0 0.7 24.2 1.4 1.5 0.0 0.0 0.0 0.4 20.9 34.0 5.9 0.1 0.0 0.4 0.1 26.9 0.9 UQCRC1 "D3S3191, QCR1, UQCR1" ENSG00000010256 "Ubiquinol-cytochrome c reductase core protein 1" P31930 3 48599002-48610976 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 766.7;tongue: 882.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 662.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002815, HPA003525, CAB033782" Enhanced Supported Mitochondria NA NA 250000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB033782: AB_2213631, HPA002815: AB_1080486, HPA003525: AB_1080484" "unprognostic (1.29e-1)" "unprognostic (3.15e-3)" "unprognostic (6.91e-3)" "unprognostic (1.06e-1)" "unprognostic (1.66e-1)" "unprognostic (9.91e-2)" "unprognostic (8.53e-2)" "unprognostic (1.99e-1)" "unprognostic (3.11e-2)" "unprognostic (9.14e-2)" "unprognostic (3.37e-1)" "unprognostic (7.20e-2)" "prognostic favorable (2.35e-10)" "unprognostic (5.37e-2)" "unprognostic (2.35e-1)" "unprognostic (1.02e-1)" "unprognostic (6.72e-2)" 66.0 58.2 93.7 46.9 97.1 62.4 55.0 117.3 110.1 50.7 127.2 156.9 156.3 35.5 50.4 78.9 66.2 33.9 387.7 96.7 115.0 131.3 149.0 42.1 42.8 111.0 101.7 36.1 87.4 192.2 30.6 56.0 114.6 51.8 129.6 52.9 105.9 77.5 766.7 78.6 125.4 62.8 99.3 41.0 103.3 52.1 111.6 72.7 48.4 882.7 58.0 63.5 40.0 101.4 118.2 169.6 136.7 145.0 147.5 117.0 225.2 129.4 206.1 196.5 178.9 272.8 107.1 193.4 94.4 143.2 274.1 123.6 171.6 280.9 91.7 138.3 173.8 214.7 186.7 317.1 186.9 164.4 152.2 150.9 293.6 183.2 274.6 167.5 172.5 173.7 110.5 107.1 152.5 192.0 156.7 241.6 157.6 229.6 324.2 103.4 138.1 273.5 235.8 178.7 84.4 107.5 182.8 218.7 211.8 92.0 163.1 178.0 112.5 107.7 153.7 179.5 272.4 124.8 121.4 136.5 192.7 233.9 319.0 251.3 643.7 325.4 204.7 665.7 193.7 260.0 203.5 206.1 593.3 227.7 177.1 175.2 158.2 194.4 608.0 235.0 258.1 988.2 93.7 97.1 117.3 110.1 96.7 115.0 111.0 101.7 114.6 99.3 111.6 101.4 31.5 57.7 50.4 17.3 59.0 117.6 164.6 339.4 103.6 41.9 59.3 46.1 662.2 140.2 139.2 121.4 29.2 334.4 28.0 550.2 365.9 163.7 155.0 64.0 41.6 53.4 144.5 80.6 16.9 166.3 311.1 78.2 167.7 61.5 82.4 72.5 49.6 188.0 238.2 40.4 22.0 319.6 223.8 118.1 85.4 331.9 58.4 107.7 119.2 12.2 129.1 67.1 51.5 14.6 12.5 163.5 333.3 70.7 117.6 78.4 553.4 398.4 104.7 65.0 59.2 61.2 153.0 110.3 74.7 173.0 105.4 336.7 50.8 172.1 416.8 153.4 UQCRC2 "QCR2, UQCR2" ENSG00000140740 "Ubiquinol-cytochrome c reductase core protein 2" P22695 16 21953288-21983660 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 722.2;tongue: 933.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 556.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007998, HPA019146" Enhanced Enhanced Mitochondria NA NA 180000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA007998: AB_1858648, HPA019146: AB_1858649" "unprognostic (1.33e-1)" "unprognostic (1.32e-1)" "unprognostic (1.49e-3)" "unprognostic (3.35e-1)" "unprognostic (1.26e-2)" "unprognostic (6.91e-2)" "unprognostic (2.71e-2)" "unprognostic (1.32e-1)" "unprognostic (1.72e-1)" "unprognostic (8.87e-2)" "unprognostic (1.67e-2)" "unprognostic (2.43e-2)" "prognostic favorable (6.58e-9)" "unprognostic (2.33e-1)" "unprognostic (9.78e-3)" "unprognostic (4.67e-3)" "unprognostic (7.36e-2)" 158.8 117.7 69.0 103.1 71.2 127.7 108.4 75.5 90.0 90.8 113.9 259.8 292.5 98.2 72.7 157.4 109.7 99.5 559.4 72.4 73.7 240.0 245.1 75.4 120.0 74.1 69.5 114.5 89.7 257.2 39.8 96.5 72.7 95.6 262.8 142.3 133.8 104.3 722.2 85.4 233.6 121.2 65.8 80.9 153.2 55.8 76.5 131.3 107.9 933.2 149.3 153.6 59.8 73.3 173.9 193.1 116.5 66.4 154.3 186.8 169.1 163.8 160.6 177.5 174.5 347.9 177.7 338.9 144.3 170.4 129.8 324.6 222.3 212.7 193.7 151.4 178.4 185.9 166.1 494.3 164.6 249.1 501.2 232.3 229.4 130.3 186.2 169.4 248.1 224.1 217.9 159.1 177.2 230.6 288.6 175.0 124.6 261.1 148.8 310.9 263.6 390.0 285.8 214.6 154.4 114.9 237.2 318.6 190.3 151.6 354.4 264.1 179.3 103.3 98.1 104.0 148.0 126.3 87.2 302.7 188.7 239.8 126.4 80.1 128.7 71.4 80.0 147.8 103.3 96.0 98.3 89.3 153.9 77.9 106.8 97.6 45.9 101.8 148.1 67.6 134.8 157.3 69.0 71.2 75.5 90.0 72.4 73.7 74.1 69.5 72.7 65.8 76.5 73.3 105.5 64.1 52.5 81.9 81.1 90.6 190.8 444.0 74.6 109.1 91.7 79.6 556.2 84.4 194.9 71.7 87.6 238.3 82.6 233.4 455.9 124.5 88.0 72.0 55.7 91.3 113.8 92.4 65.0 109.6 157.6 89.0 144.3 65.8 92.6 99.6 84.3 122.3 195.5 69.0 74.0 224.4 238.0 145.1 100.6 89.9 68.3 104.6 131.6 27.2 162.1 108.0 91.6 60.3 50.7 97.2 214.0 97.0 72.9 114.4 378.0 306.9 110.2 152.6 78.9 94.1 109.5 68.9 56.7 132.0 88.4 278.3 91.3 170.2 358.7 204.3 UQCRFS1 "RIP1, RIS1, RISP, UQCR5" ENSG00000169021 "Ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1" P47985 19 29205320-29213151 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 231.6;tongue: 285.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1474.9;Distal tubular cells: 1035.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041863, HPA050339" Enhanced Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA041863: AB_10794638, HPA050339: AB_2681095" "unprognostic (4.00e-2)" "unprognostic (2.23e-3)" "prognostic favorable (3.29e-4)" "unprognostic (7.91e-3)" "unprognostic (3.93e-2)" "unprognostic (8.68e-2)" "unprognostic (1.84e-1)" "unprognostic (7.53e-2)" "unprognostic (3.53e-2)" "prognostic unfavorable (3.84e-4)" "unprognostic (1.73e-2)" "unprognostic (1.66e-1)" "prognostic favorable (3.92e-9)" "unprognostic (6.11e-2)" "unprognostic (2.96e-1)" "unprognostic (1.45e-1)" "unprognostic (1.92e-2)" 28.7 50.1 25.6 17.4 26.7 52.8 24.7 29.4 31.1 18.3 33.6 49.0 43.2 19.2 23.1 33.2 19.3 13.2 138.3 27.2 28.4 62.5 50.9 17.6 17.2 27.0 27.4 15.4 29.4 47.3 19.9 17.3 26.1 18.8 52.6 26.6 26.7 21.9 231.6 27.9 34.0 24.8 26.4 21.1 39.3 25.9 29.3 26.0 16.8 285.9 25.9 25.7 20.3 26.0 63.0 103.7 37.7 34.1 60.6 45.9 41.8 47.8 49.7 64.7 71.1 63.3 37.7 56.7 49.2 54.4 52.7 64.8 83.4 56.9 77.6 38.7 83.2 80.2 39.2 58.1 51.3 77.2 67.5 55.5 60.4 44.2 66.9 38.0 52.4 69.0 58.0 34.5 70.2 58.0 54.5 57.6 39.6 132.2 39.7 48.9 50.3 43.1 80.9 74.4 45.8 22.4 43.5 84.9 58.2 42.0 39.6 63.4 33.4 43.5 66.4 30.2 50.4 16.4 33.3 52.5 38.4 66.4 31.7 51.4 90.7 43.8 50.0 90.9 50.3 54.8 53.2 51.9 106.6 48.0 56.1 53.6 27.3 49.2 78.3 59.3 68.4 166.2 25.6 26.7 29.4 31.1 27.2 28.4 27.0 27.4 26.1 26.4 29.3 26.0 69.7 54.5 46.6 16.6 104.9 147.6 279.7 466.7 105.9 71.8 119.5 128.4 1474.9 161.5 201.4 114.0 16.7 282.0 116.8 321.6 1035.0 245.2 258.4 106.1 66.8 106.8 160.0 147.9 18.1 235.1 271.7 126.7 139.7 88.5 90.7 114.2 83.9 272.1 266.1 52.2 19.2 293.6 317.3 160.6 109.6 146.0 92.2 136.6 165.4 13.1 206.6 124.6 132.8 19.6 15.8 205.0 225.8 81.6 159.4 257.3 338.6 758.4 132.4 84.1 98.6 107.5 131.0 348.8 80.5 203.9 160.3 381.9 109.5 209.1 407.4 372.1 UQCRQ "QCR8, QP-C, UQCR7" ENSG00000164405 "Ubiquinol-cytochrome c reductase complex III subunit VII" O14949 5 132866630-132868847 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1301.6" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 3312.4;Hepatocytes: 5039.2;Proximal tubular cells: 3336.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046693, HPA053323" Approved Enhanced Mitochondria NA NA 18000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA046693: AB_10968453, HPA053323: AB_2682112" "unprognostic (3.22e-1)" "unprognostic (1.06e-1)" "unprognostic (4.92e-2)" "prognostic favorable (4.23e-4)" "unprognostic (1.09e-1)" "unprognostic (9.03e-2)" "unprognostic (1.02e-1)" "unprognostic (3.45e-2)" "unprognostic (1.37e-1)" "unprognostic (3.72e-2)" "unprognostic (7.31e-2)" "unprognostic (3.49e-1)" "unprognostic (1.81e-3)" "unprognostic (1.06e-1)" "unprognostic (1.84e-1)" "unprognostic (2.33e-1)" "unprognostic (3.37e-2)" 226.5 378.7 277.6 91.8 283.7 132.6 189.2 309.6 391.9 151.7 293.2 313.0 220.8 147.9 211.2 332.4 138.6 78.3 1301.6 283.6 315.5 460.7 1036.6 149.0 69.1 291.2 285.6 120.0 269.4 318.5 222.8 89.0 294.9 272.9 232.2 187.4 253.8 122.2 1024.7 182.3 244.5 98.5 286.6 151.8 372.3 128.9 294.7 130.3 167.3 873.5 92.3 219.9 193.3 302.3 300.9 391.1 246.7 599.9 364.2 292.2 209.3 216.3 310.6 341.7 424.9 556.4 353.8 126.5 433.4 291.5 424.5 302.7 229.5 536.6 300.7 222.9 466.0 169.4 606.3 459.9 312.7 188.8 276.2 314.0 366.5 247.4 341.6 229.6 274.1 258.3 219.2 398.6 369.7 547.5 450.5 442.1 175.3 568.1 367.0 288.4 271.7 541.7 460.9 573.4 410.7 335.8 269.1 302.7 493.9 170.4 451.9 422.5 168.3 316.0 392.1 257.2 438.7 423.1 616.3 236.6 417.9 350.0 320.6 474.1 528.3 355.5 245.6 431.0 251.8 317.2 280.3 280.2 472.0 260.6 273.5 263.6 258.8 322.9 410.0 516.7 326.1 658.2 277.6 283.7 309.6 391.9 283.6 315.5 291.2 285.6 294.9 286.6 294.7 302.3 252.0 250.0 349.3 17.6 258.1 348.3 334.0 1046.6 235.6 97.8 575.5 657.7 3312.4 993.7 556.9 787.2 120.9 720.4 200.6 1678.3 1813.7 685.6 470.0 424.1 308.5 288.4 549.3 319.4 13.9 947.7 484.1 330.2 438.3 467.5 294.5 277.0 333.8 5039.2 771.4 72.3 17.0 1047.6 807.7 421.1 448.6 1116.6 282.4 301.6 715.1 11.2 394.7 459.2 260.6 13.6 23.5 705.7 1460.8 288.9 416.2 537.1 2476.1 3336.0 512.5 271.5 184.1 217.8 388.7 308.1 174.7 570.1 514.0 562.7 205.0 235.9 1205.6 500.2 USP54 "bA137L10.3, bA137L10.4, C10orf29, FLJ37318" ENSG00000166348 "Ubiquitin specific peptidase 54" Q70EL1 10 73497538-73625994 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 134.8" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 476.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "OE19: 33.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047663, HPA063665" Approved Approved Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 70: Brain - Nervous system development" "Cluster 21: OE19 - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA047663: AB_2680116, HPA063665: " "unprognostic (2.46e-2)" "unprognostic (1.67e-1)" "unprognostic (3.17e-2)" "unprognostic (1.89e-2)" "unprognostic (2.48e-2)" "unprognostic (4.89e-3)" "unprognostic (6.63e-4)" "prognostic favorable (7.00e-4)" "unprognostic (6.24e-2)" "unprognostic (4.35e-2)" "unprognostic (8.91e-3)" "unprognostic (3.49e-1)" "unprognostic (1.95e-3)" "unprognostic (8.18e-2)" "unprognostic (6.88e-2)" "unprognostic (1.65e-2)" "unprognostic (1.31e-1)" 4.6 3.1 61.5 5.5 103.5 2.1 16.3 85.5 72.4 14.5 32.2 15.0 4.9 9.3 13.2 13.9 12.0 5.6 7.0 60.5 71.9 5.2 1.5 17.9 2.8 99.8 97.5 6.8 10.8 8.9 2.9 2.8 94.0 12.1 19.7 14.8 16.8 7.6 49.7 15.2 6.7 7.1 70.4 2.9 20.7 9.1 85.0 8.4 40.7 17.0 7.1 6.6 4.9 134.8 10.0 8.4 15.9 13.7 4.4 4.8 4.7 4.7 11.2 7.9 8.6 8.1 16.7 6.6 6.5 3.7 6.1 14.2 10.7 4.3 10.2 2.8 8.6 5.0 6.3 8.0 4.1 5.6 2.3 3.9 3.8 9.0 10.9 20.6 3.4 5.7 7.5 3.0 6.3 5.6 4.5 6.8 8.0 33.4 30.2 7.0 11.9 3.0 8.7 7.6 4.8 5.4 10.1 11.7 15.8 10.2 15.8 5.8 4.9 3.5 11.2 6.6 6.8 2.4 4.3 4.1 8.3 5.3 3.1 0.2 0.4 0.5 0.6 0.4 0.7 0.4 0.5 0.4 0.4 0.3 0.7 0.4 0.0 0.3 0.5 0.4 0.6 0.4 61.5 103.5 85.5 72.4 60.5 71.9 99.8 97.5 94.0 70.4 85.0 134.8 5.9 48.1 34.3 33.0 1.7 2.7 8.5 11.0 4.0 7.7 15.3 8.4 7.2 5.7 18.9 12.9 16.7 1.0 1.2 19.6 0.0 4.7 2.4 25.8 12.9 6.3 10.3 2.1 23.1 8.0 1.0 7.6 40.2 44.3 3.8 3.5 2.5 3.0 1.4 5.0 33.4 23.4 2.0 1.3 1.4 2.2 3.4 1.8 8.8 76.8 0.8 12.5 0.0 116.1 476.0 12.2 9.7 10.9 2.3 52.6 10.5 1.9 21.7 12.2 6.6 19.6 3.8 9.2 6.0 7.7 4.0 1.4 3.0 2.9 11.2 15.2 VARS2 "DKFZP434L1435, G7a, KIAA1885, VARS2L, VARSL" ENSG00000137411 "Valyl-tRNA synthetase 2, mitochondrial" Q5ST30 6 30914205-30926459 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062449, HPA070267" Approved Approved Mitochondria NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 72: Non-specific - Transcription" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA062449: AB_2684766, HPA070267: AB_2686245" "unprognostic (1.74e-1)" "unprognostic (8.24e-2)" "unprognostic (1.96e-3)" "unprognostic (2.50e-1)" "unprognostic (5.80e-2)" "unprognostic (3.05e-2)" "unprognostic (2.43e-2)" "unprognostic (1.66e-2)" "unprognostic (3.14e-1)" "unprognostic (8.98e-2)" "unprognostic (4.23e-2)" "unprognostic (2.60e-2)" "unprognostic (2.15e-3)" "unprognostic (1.04e-2)" "unprognostic (7.23e-2)" "unprognostic (1.19e-2)" "unprognostic (2.43e-2)" 10.2 14.4 1.3 2.1 1.5 1.9 9.7 1.5 1.6 12.5 0.4 10.5 1.2 10.4 1.5 22.5 10.1 0.2 11.1 1.4 1.3 12.5 18.9 10.5 3.1 1.3 1.6 15.3 14.0 2.3 17.1 0.9 1.4 10.2 2.2 1.4 10.9 1.1 20.9 10.1 12.8 0.7 1.2 13.4 11.7 11.8 1.3 4.1 15.0 0.2 2.3 10.5 13.2 1.3 13.8 9.6 5.5 23.1 4.9 4.4 0.7 2.2 1.9 2.5 1.6 12.6 8.9 11.9 7.5 3.0 9.4 0.0 21.3 0.0 2.4 4.6 15.7 13.2 10.2 0.9 6.7 2.3 0.3 6.2 8.1 5.9 1.3 0.9 1.3 19.5 0.1 10.5 5.4 0.0 4.6 0.0 1.7 0.0 1.2 9.1 0.0 10.3 18.3 0.0 8.5 0.2 0.2 6.6 5.4 5.0 16.3 7.4 2.2 14.2 1.4 1.0 0.1 10.0 17.1 18.8 0.0 0.6 8.7 0.0 0.0 0.0 0.3 0.1 0.4 0.3 0.1 0.3 0.2 0.1 0.1 0.1 0.0 0.0 0.2 0.3 0.2 0.1 1.3 1.5 1.5 1.6 1.4 1.3 1.3 1.6 1.4 1.2 1.3 1.3 3.0 6.4 12.5 14.7 8.0 4.0 4.9 4.7 4.0 6.6 6.4 3.7 11.6 8.6 5.5 9.2 0.0 8.7 4.1 10.1 1.9 6.7 1.5 7.7 5.2 3.9 13.1 3.4 8.3 7.1 9.6 4.8 11.7 8.6 12.7 12.9 7.5 22.5 9.2 8.4 9.1 8.4 2.0 6.9 3.5 1.6 4.1 5.1 1.8 3.7 7.9 2.8 4.1 8.0 7.2 8.9 4.7 4.1 12.3 2.3 12.4 12.5 8.9 6.0 0.0 2.9 3.7 10.4 8.0 9.0 4.1 3.4 4.8 6.9 10.9 3.8 VDAC2 ENSG00000165637 "Voltage dependent anion channel 2" P45880 10 75210154-75231448 "Predicted intracellular proteins, Transporters" "Ion transport, Transport" Porin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043475 Enhanced Supported Mitochondria NA NA 490000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 16: Pancreatic endocrine cells - Mixed function" Mitochondria "HPA043475: AB_10795615" "unprognostic (1.01e-2)" "unprognostic (1.22e-1)" "unprognostic (9.47e-2)" "unprognostic (9.00e-3)" "unprognostic (5.74e-2)" "prognostic unfavorable (4.51e-4)" "prognostic unfavorable (4.55e-4)" "unprognostic (1.83e-3)" "unprognostic (5.89e-2)" "unprognostic (2.45e-1)" "unprognostic (2.02e-2)" "unprognostic (1.56e-2)" "unprognostic (4.27e-2)" "unprognostic (1.40e-1)" "unprognostic (1.65e-1)" "unprognostic (6.28e-2)" "unprognostic (1.34e-2)" 138.2 150.3 95.5 93.3 97.4 138.5 116.2 116.2 115.0 165.5 117.1 209.1 151.3 116.6 90.7 322.1 117.4 85.4 420.5 99.0 109.0 177.5 115.9 112.0 83.5 105.7 107.1 132.8 150.6 192.7 85.3 115.6 110.1 108.8 184.4 198.4 151.4 134.0 539.4 171.6 148.4 149.2 105.0 77.7 159.4 104.6 107.1 92.7 111.0 565.9 148.3 163.6 207.1 110.4 304.4 245.0 291.0 370.5 253.3 342.1 305.2 384.9 430.4 412.7 386.6 367.5 281.8 358.6 210.9 324.3 228.6 398.2 539.2 382.2 402.1 196.0 313.5 209.4 191.4 425.2 252.6 402.0 223.4 305.6 441.7 352.8 747.3 578.2 310.0 222.9 359.9 283.7 439.4 222.6 262.6 325.7 250.7 341.2 937.6 308.2 230.0 228.3 408.9 187.5 183.4 216.5 212.4 701.7 467.4 337.8 409.7 177.4 241.4 204.4 279.8 305.7 419.8 226.7 333.1 369.0 296.3 390.4 178.1 168.2 179.0 138.9 106.7 193.1 130.8 154.2 144.3 119.4 220.4 127.9 144.2 134.5 61.5 135.5 238.4 107.3 178.6 221.6 95.5 97.4 116.2 115.0 99.0 109.0 105.7 107.1 110.1 105.0 107.1 110.4 130.3 96.1 54.9 30.3 135.5 381.4 417.8 575.6 280.6 149.6 149.5 159.1 325.1 128.7 246.3 112.2 43.8 315.0 128.0 583.7 669.1 413.3 257.6 172.2 110.9 146.5 149.7 148.5 22.1 345.7 437.6 142.6 158.0 199.9 112.3 197.5 165.9 79.2 266.1 129.5 30.7 305.1 284.8 164.8 220.3 110.8 169.9 180.2 224.1 16.9 264.3 275.5 92.7 23.1 26.0 443.5 497.2 166.3 172.2 386.3 610.9 324.3 119.5 161.1 177.5 170.3 289.0 359.7 149.7 493.3 420.4 396.5 129.6 210.5 355.7 568.1 VDAC3 HD-VDAC3 ENSG00000078668 "Voltage dependent anion channel 3" Q9Y277 8 42391624-42405937 "Plasma proteins, Predicted intracellular proteins" "Ion transport, Transport" Porin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "heart muscle: 385.2;skeletal muscle: 914.4;tongue: 942.7" "Cell type enhanced" "Detected in all" "Spermatocytes: 403.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026864 Uncertain Supported Mitochondria NA NA 1200000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA026864: AB_1858733" "unprognostic (2.55e-2)" "unprognostic (1.96e-2)" "unprognostic (9.88e-3)" "unprognostic (4.40e-2)" "unprognostic (1.26e-1)" "unprognostic (2.00e-1)" "unprognostic (4.98e-2)" "unprognostic (2.25e-2)" "unprognostic (1.40e-2)" "unprognostic (5.76e-2)" "unprognostic (3.74e-1)" "unprognostic (1.19e-2)" "unprognostic (6.16e-3)" "unprognostic (2.96e-2)" "unprognostic (1.76e-1)" "unprognostic (8.78e-3)" "unprognostic (6.94e-3)" 67.5 76.2 117.3 59.1 119.4 92.1 70.3 116.8 150.6 53.7 115.4 106.9 79.8 63.5 68.6 99.9 85.8 56.0 385.2 121.1 130.8 108.8 92.9 51.9 66.3 122.7 119.3 61.6 64.6 92.4 58.9 63.9 139.2 69.5 106.4 123.1 61.6 81.3 914.4 54.1 73.0 92.8 114.1 67.3 72.1 114.5 118.6 80.1 83.3 942.7 79.3 78.9 59.8 113.8 226.3 225.7 174.5 185.9 146.3 126.6 84.8 180.0 151.1 225.4 205.2 173.4 190.4 235.8 165.0 153.7 196.3 142.5 238.4 194.1 244.7 117.2 196.6 352.9 138.4 250.2 105.2 172.0 190.1 98.6 143.3 171.6 80.9 149.6 279.8 201.3 284.4 158.6 235.7 126.4 373.3 197.1 205.2 285.6 144.5 193.6 322.1 165.3 245.7 198.8 156.8 133.3 112.1 132.8 116.1 126.4 279.9 129.9 149.8 86.6 150.0 217.7 174.0 145.2 264.1 266.9 117.5 238.0 150.9 142.8 165.3 183.4 145.8 167.2 148.7 126.5 155.6 146.5 222.7 96.6 152.7 147.7 82.8 125.8 155.6 163.0 202.5 360.5 117.3 119.4 116.8 150.6 121.1 130.8 122.7 119.3 139.2 114.1 118.6 113.8 78.1 44.8 24.4 50.6 59.8 64.5 81.1 197.8 58.1 85.9 53.0 73.9 321.2 55.8 82.8 66.2 35.5 145.5 91.9 65.7 307.2 116.3 151.1 112.8 56.7 70.5 47.8 186.4 63.2 90.0 112.1 81.5 41.3 47.1 55.2 100.6 68.2 60.4 139.7 138.0 78.9 86.1 177.0 58.5 77.8 146.4 69.3 107.7 72.9 26.2 130.1 72.9 83.4 38.2 34.7 84.9 86.7 97.4 75.9 48.9 125.3 177.5 142.1 94.5 65.7 146.4 123.8 403.7 156.3 82.3 70.8 58.3 79.7 94.2 124.8 70.4 VPS26C "DCRA, DSCR3" ENSG00000157538 "VPS26 endosomal protein sorting factor C" O14972 21 37223420-37267919 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 26.4;Exocrine glandular cells: 28.0;Extravillous trophoblasts: 26.4;Hofbauer cells: 32.7;Pancreatic endocrine cells: 33.2;Proximal tubular cells: 29.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023288 Uncertain Approved Mitochondria NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA023288: AB_1847872" "unprognostic (1.01e-3)" "unprognostic (6.42e-2)" "unprognostic (7.96e-3)" "unprognostic (2.15e-2)" "unprognostic (4.10e-3)" "unprognostic (2.04e-1)" "unprognostic (1.88e-2)" "unprognostic (1.40e-1)" "unprognostic (3.15e-1)" "unprognostic (7.76e-2)" "unprognostic (5.40e-2)" "unprognostic (1.97e-1)" "prognostic favorable (8.54e-4)" "unprognostic (1.72e-1)" "unprognostic (3.24e-1)" "unprognostic (5.24e-2)" "unprognostic (3.16e-1)" 19.8 24.5 14.8 18.5 16.1 21.4 15.8 16.8 15.8 16.3 15.9 26.6 28.0 14.8 11.4 21.2 13.8 19.6 24.9 14.4 15.6 32.9 29.5 22.1 22.6 16.1 15.9 17.4 22.6 17.7 8.6 21.4 16.6 14.3 26.0 13.6 16.9 15.8 31.5 15.7 26.9 19.9 16.2 20.2 21.2 7.5 16.5 28.1 18.1 37.8 23.6 21.9 14.2 17.6 31.8 13.8 30.2 26.5 55.4 49.4 34.3 29.9 66.2 26.6 40.2 19.2 32.7 22.0 11.7 70.0 63.9 15.0 32.6 32.1 26.1 52.8 23.5 37.6 13.6 18.7 49.1 27.8 24.3 43.5 31.2 31.0 50.4 48.1 51.4 40.5 24.0 46.8 52.5 14.1 47.2 23.7 34.4 48.7 13.8 44.8 14.5 32.5 32.8 23.7 24.4 32.6 20.6 40.9 65.5 39.0 38.4 22.0 41.0 30.6 10.8 33.2 18.5 71.3 78.0 30.3 48.3 47.9 35.2 58.6 48.6 84.9 50.7 60.5 46.8 37.5 43.1 45.4 47.7 29.4 39.8 41.0 50.1 52.9 55.7 19.4 54.9 54.1 14.8 16.1 16.8 15.8 14.4 15.6 16.1 15.9 16.6 16.2 16.5 17.6 18.1 9.6 21.9 0.0 4.3 0.0 0.0 0.0 0.0 0.0 14.5 13.3 0.0 0.0 6.8 9.2 0.0 16.0 23.8 0.0 21.5 26.4 0.0 12.5 12.7 8.4 0.0 0.0 0.0 28.0 26.4 5.4 0.0 16.1 8.8 19.0 0.0 0.0 32.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.3 0.0 0.0 16.5 0.0 0.0 0.0 0.0 33.2 0.0 0.0 3.1 0.0 0.0 29.7 4.4 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 14.6 8.5 10.1 0.0 0.0 VPS35L "C16orf62, MGC16824" ENSG00000103544 "VPS35 endosomal protein sorting factor like" Q7Z3J2 16 19555240-19706793 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 32.4;Cytotrophoblasts: 29.4;Distal tubular cells: 29.4;Hofbauer cells: 44.9;Syncytiotrophoblasts: 40.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042969, HPA053547" Uncertain Approved Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA042969: AB_10794920, HPA053547: AB_2682183" "unprognostic (7.15e-2)" "unprognostic (6.54e-2)" "unprognostic (1.17e-1)" "unprognostic (7.20e-2)" "unprognostic (1.51e-1)" "unprognostic (2.67e-1)" "unprognostic (1.15e-1)" "unprognostic (2.74e-1)" "unprognostic (2.52e-1)" "unprognostic (1.22e-3)" "unprognostic (3.57e-2)" "unprognostic (2.06e-1)" "prognostic favorable (1.31e-8)" "unprognostic (1.82e-3)" "unprognostic (8.92e-2)" "unprognostic (5.08e-2)" "unprognostic (1.13e-2)" 19.3 22.7 23.3 15.9 33.5 13.2 17.1 21.8 24.9 21.2 11.7 19.2 13.7 20.1 22.4 16.8 19.2 17.5 17.8 20.7 23.5 22.2 14.4 16.2 14.6 23.3 24.4 23.3 16.5 35.6 20.4 20.2 24.6 15.9 19.4 16.1 12.4 18.9 22.2 13.8 15.3 25.1 20.5 17.2 13.3 31.5 28.0 16.1 22.7 25.2 16.6 18.3 15.6 40.3 22.3 37.5 35.7 28.4 44.2 60.1 5.8 32.5 52.3 33.9 38.9 6.4 37.0 27.1 67.4 51.7 0.2 6.2 27.5 16.7 36.5 1.6 15.7 16.4 32.6 0.6 57.4 25.9 31.6 43.9 24.4 31.7 21.5 48.2 54.4 13.2 22.3 6.2 55.7 15.7 23.0 7.2 24.8 3.9 5.1 19.6 11.7 7.1 38.6 5.2 21.8 22.1 43.7 1.5 18.6 27.2 12.9 22.2 61.0 17.4 16.2 25.7 3.7 23.8 45.2 10.6 33.6 21.1 27.5 26.5 35.3 16.5 18.9 42.0 23.5 14.7 18.0 18.8 42.6 23.5 21.0 18.6 4.2 37.6 37.7 11.5 21.6 28.5 23.3 33.5 21.8 24.9 20.7 23.5 23.3 24.4 24.6 20.5 28.0 40.3 32.4 6.4 16.4 0.0 3.0 0.0 0.0 0.0 0.0 0.0 9.5 9.1 0.0 0.0 8.1 16.5 0.0 29.4 5.0 0.0 29.4 20.4 0.0 8.2 15.8 15.5 0.0 0.0 0.0 17.0 19.5 8.1 0.0 11.1 3.8 18.1 0.0 0.0 44.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 10.5 0.0 0.0 1.2 0.0 0.0 21.9 2.9 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 40.2 3.4 21.0 0.0 0.0 WARS2 mtTrpRS ENSG00000116874 "Tryptophanyl tRNA synthetase 2, mitochondrial" Q9UGM6 1 119031216-119140654 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 57.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028007, HPA069692" Enhanced Supported Mitochondria NA NA "Cluster 24: B-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 34: Spermatids - Unknown function" Mitochondria "HPA028007: , HPA069692: AB_2686172" "unprognostic (1.00e-1)" "unprognostic (2.25e-1)" "unprognostic (2.03e-1)" "unprognostic (5.64e-2)" "unprognostic (3.42e-1)" "unprognostic (7.05e-2)" "unprognostic (7.73e-3)" "unprognostic (3.72e-1)" "unprognostic (2.14e-2)" "unprognostic (1.17e-2)" "unprognostic (3.96e-2)" "unprognostic (6.76e-3)" "prognostic favorable (1.45e-4)" "unprognostic (4.83e-2)" "unprognostic (1.83e-1)" "unprognostic (9.88e-3)" "unprognostic (4.71e-2)" 7.3 8.8 2.4 4.1 2.4 1.9 9.4 2.4 3.0 6.9 6.5 7.3 7.7 6.3 3.8 6.1 9.4 4.9 7.9 2.3 2.6 9.6 6.1 5.0 4.7 2.4 2.4 8.2 8.9 10.2 3.8 6.3 2.4 5.7 8.0 6.0 5.4 3.5 6.3 5.2 5.1 5.2 2.4 3.0 7.2 4.6 2.3 4.6 6.8 6.5 5.1 6.8 5.6 2.8 12.8 5.0 7.5 7.9 9.6 21.6 7.6 7.0 10.5 7.6 9.1 14.4 5.6 19.0 11.4 12.0 4.2 8.2 13.9 12.6 11.7 9.8 16.6 8.9 12.8 13.9 19.6 14.8 4.8 16.1 9.7 11.1 20.2 10.0 11.7 7.9 14.1 13.4 14.4 15.7 8.9 8.6 9.9 9.8 10.6 6.3 24.9 9.9 20.9 17.5 10.7 6.6 11.3 15.4 16.7 13.1 6.9 11.1 8.8 7.8 9.2 15.2 13.8 6.4 4.6 8.3 9.6 12.1 14.7 0.0 5.0 0.3 3.4 3.6 5.0 4.6 3.6 4.5 6.7 6.2 4.2 4.2 0.2 4.2 2.2 3.2 4.5 3.4 2.4 2.4 2.4 3.0 2.3 2.6 2.4 2.4 2.4 2.4 2.3 2.8 7.2 9.6 12.3 22.5 10.4 9.6 17.6 14.7 14.2 6.7 13.1 11.3 10.6 5.7 11.2 11.0 6.2 16.9 7.0 6.5 17.6 9.8 57.7 15.2 8.6 7.5 6.7 18.9 15.5 11.9 15.3 15.5 17.9 13.8 8.8 9.7 2.2 7.5 9.5 6.7 21.4 10.2 14.2 10.0 6.9 31.8 9.9 8.2 10.6 11.2 13.0 5.0 3.1 12.1 18.2 8.7 6.1 8.2 9.1 13.1 7.5 18.8 14.7 8.2 6.6 12.0 10.1 5.4 6.1 19.8 10.7 20.0 10.2 19.6 15.8 14.4 WIPF3 "CR16, FLJ36931" ENSG00000122574 "WAS/WASL interacting protein family member 3" A6NGB9 7 29806486-29917066 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.9;ovary: 41.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 45.1;Granulosa cells: 149.4;Leydig cells: 50.7;Peritubular cells: 100.4" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basal ganglia: 22.1;cerebral cortex: 49.9;hippocampal formation: 40.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 18.1;HEK 293: 4.1;K-562: 6.6;NTERA-2: 5.1;RPMI-8226: 11.3;SK-MEL-30: 4.5" "Region enhanced" "Detected in all" "hippocampal formation: 213.9" "Region enhanced" "Detected in all" "hippocampal formation: 156.3" "HPA041145, HPA041211" Uncertain Uncertain Mitochondria NA NA "Cluster 42: Non-specific - Transcription" "Cluster 47: Non-specific - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "HPA041145: AB_10795001, HPA041211: AB_10795003" "prognostic favorable (7.93e-4)" "unprognostic (1.35e-1)" "unprognostic (1.37e-3)" "unprognostic (2.12e-3)" "unprognostic (3.65e-3)" "unprognostic (1.53e-1)" "unprognostic (8.95e-3)" "unprognostic (4.53e-2)" "unprognostic (3.49e-1)" "unprognostic (1.19e-2)" "unprognostic (1.08e-2)" "unprognostic (7.49e-2)" "unprognostic (1.61e-2)" "unprognostic (1.35e-1)" "unprognostic (2.27e-2)" "unprognostic (3.33e-2)" "unprognostic (1.41e-1)" 1.0 5.6 8.7 1.0 22.1 0.5 1.1 0.0 49.9 0.4 0.0 0.7 2.9 3.3 19.7 1.2 8.8 1.4 4.0 40.3 4.2 2.5 0.5 0.5 0.7 0.4 2.6 41.7 1.7 1.2 0.9 0.2 0.1 4.4 0.5 3.8 4.0 4.8 25.0 0.9 2.6 4.1 0.5 1.0 5.9 18.8 7.4 0.4 2.0 8.8 0.7 1.4 0.2 8.1 0.3 1.1 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.9 0.0 0.2 0.0 18.1 0.0 0.0 0.0 4.1 0.0 0.1 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 6.6 0.1 0.0 0.1 0.0 0.0 5.1 0.0 3.6 0.0 0.0 11.3 0.0 0.0 1.8 1.5 0.1 0.1 4.5 2.4 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.2 0.1 0.2 0.1 0.2 0.3 0.1 0.0 8.7 22.1 0.0 49.9 40.3 4.2 0.4 2.6 0.1 0.5 7.4 8.1 1.5 0.0 0.0 6.2 0.0 2.2 1.5 0.6 1.2 8.2 4.9 4.6 9.3 0.0 1.4 3.7 2.1 0.0 0.3 0.5 3.9 3.8 1.8 5.0 0.4 4.1 1.8 3.0 45.1 3.5 0.1 7.3 11.7 1.2 0.0 149.4 0.4 0.5 4.5 5.0 27.0 0.7 0.0 0.0 1.0 4.8 50.7 1.0 5.4 1.9 0.0 6.2 0.0 2.0 1.9 2.4 1.5 100.4 0.1 1.1 5.5 5.5 5.1 2.9 6.6 7.2 16.0 4.4 9.9 0.9 0.4 0.0 1.0 8.7 2.0 0.4 WSB1 "DKFZp564A122, DKFZp564B0482, SWIP1" ENSG00000109046 "WD repeat and SOCS box containing 1" Q9Y6I7 17 27294076-27315926 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003293 Approved Approved Mitochondria NA Yes "Cluster 45: Eosinophils - Innate immune response" "Cluster 19: Lung - Lung function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 41: Macrophages - Immune response" Mitochondria "HPA003293: AB_1858863" "unprognostic (1.73e-1)" "unprognostic (5.13e-2)" "unprognostic (1.25e-1)" "unprognostic (1.44e-1)" "unprognostic (2.14e-1)" "unprognostic (2.66e-1)" "prognostic unfavorable (4.07e-5)" "unprognostic (2.59e-2)" "unprognostic (5.40e-3)" "unprognostic (2.74e-1)" "unprognostic (9.22e-2)" "unprognostic (1.69e-2)" "prognostic unfavorable (1.02e-7)" "unprognostic (1.44e-1)" "unprognostic (3.18e-1)" "unprognostic (1.62e-1)" "unprognostic (3.74e-2)" 41.9 22.1 14.1 45.9 35.7 48.7 35.7 22.9 26.9 47.0 5.2 40.7 28.6 49.4 24.6 27.7 45.9 39.6 32.5 14.1 35.9 29.0 15.6 58.3 34.5 38.7 22.7 47.7 29.6 19.0 23.8 75.0 40.6 27.6 30.9 76.0 27.4 32.1 23.0 23.2 33.7 44.8 17.0 69.9 32.7 21.6 33.2 24.8 28.8 16.1 35.2 32.8 39.1 80.0 30.8 21.3 65.3 37.5 40.3 49.7 69.7 26.6 37.9 20.6 39.6 32.0 12.2 30.6 29.6 36.6 26.2 28.4 40.0 19.6 30.9 85.3 33.1 48.7 41.9 32.7 75.7 34.1 69.2 60.2 26.3 30.1 18.4 31.5 83.1 31.7 49.8 28.6 36.9 19.4 44.4 38.4 19.4 17.1 17.3 35.5 35.9 18.5 31.1 24.6 20.9 28.8 27.8 27.3 36.7 77.8 22.1 44.5 46.5 25.3 19.2 34.8 26.4 12.8 34.9 31.2 23.9 26.8 23.4 75.0 41.1 71.5 21.6 70.3 26.1 22.1 18.1 24.2 65.5 25.3 17.0 19.7 37.1 21.4 82.5 21.5 30.2 26.4 14.1 35.7 22.9 26.9 14.1 35.9 38.7 22.7 40.6 17.0 33.2 80.0 300.4 221.2 476.1 189.7 245.4 249.2 185.6 138.4 253.8 91.9 186.7 147.7 67.5 144.4 194.2 239.1 348.2 360.7 183.2 222.7 27.4 124.9 153.0 201.2 187.6 254.9 194.4 148.1 229.5 65.1 217.2 284.6 190.6 301.5 163.5 436.3 316.6 43.3 228.2 82.4 267.8 191.5 162.8 412.6 288.9 26.6 141.4 358.9 197.5 206.1 153.2 170.5 112.3 349.3 658.2 76.7 185.4 122.6 144.9 196.3 178.7 30.7 137.5 381.4 124.9 243.8 221.9 119.6 104.8 202.2 280.3 714.5 183.9 98.5 133.6 148.9 XKR9 ENSG00000221947 "XK related 9" Q5GH70 8 70669339-70790371 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 5.3;testis: 7.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 42.0;Inhibitory neurons: 17.9;Oligodendrocytes: 23.0;Spermatocytes: 82.3;Spermatogonia: 19.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 3.3;hTCEpi: 6.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA044430 Enhanced Approved Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 45: Intestine - Brush border" "Cluster 30: Epithelial cell lines - Translation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Mitochondria "HPA044430: AB_10961283" "unprognostic (1.79e-2)" "unprognostic (7.31e-2)" "unprognostic (1.42e-1)" "unprognostic (1.40e-3)" "unprognostic (1.85e-1)" "unprognostic (1.22e-1)" "unprognostic (2.23e-2)" "unprognostic (9.33e-2)" "unprognostic (1.63e-1)" "unprognostic (2.63e-2)" "prognostic unfavorable (7.20e-4)" "unprognostic (2.29e-1)" "unprognostic (6.96e-6)" "unprognostic (3.65e-1)" "unprognostic (3.26e-1)" "unprognostic (4.04e-3)" "unprognostic (3.71e-2)" 0.2 1.1 0.5 0.4 0.5 0.5 0.4 0.0 1.6 0.2 0.0 0.9 2.6 0.2 1.3 0.5 0.1 2.2 0.2 0.5 0.3 0.5 3.3 0.6 0.5 0.6 0.2 0.2 0.3 0.1 0.6 0.4 1.1 0.6 0.5 2.4 0.5 0.0 0.2 0.9 5.3 0.3 0.0 0.5 1.8 7.7 0.3 0.5 0.4 0.3 0.5 1.0 0.2 1.5 2.3 0.1 0.5 0.2 0.0 0.5 0.3 0.9 0.4 0.3 0.9 3.3 0.2 0.3 1.5 0.0 1.1 0.1 0.0 0.5 1.1 0.4 0.3 0.2 0.2 0.2 0.0 0.7 1.2 0.6 6.4 0.1 0.0 0.2 0.0 1.6 0.1 2.3 0.1 0.3 0.4 0.3 1.3 0.1 0.4 0.3 0.6 0.1 0.1 1.7 1.4 0.2 0.4 1.0 0.3 0.1 0.3 0.1 0.2 0.3 0.6 0.4 0.3 2.0 0.5 1.5 0.1 0.2 0.2 0.2 0.0 0.0 0.2 0.0 0.4 0.2 0.4 0.2 0.0 0.2 0.6 0.4 0.1 0.2 0.0 0.0 0.8 0.0 0.5 0.5 0.0 1.6 0.5 0.3 0.6 0.2 1.1 0.0 0.3 1.5 0.1 6.4 2.2 14.4 1.1 2.7 3.5 3.9 4.6 2.2 0.7 1.0 0.4 1.5 3.3 0.0 8.4 1.0 0.3 1.4 0.0 1.6 5.3 0.5 0.3 0.6 0.0 0.0 42.0 4.6 0.6 0.8 6.1 0.6 0.0 0.3 0.0 2.3 0.3 1.7 17.9 3.4 0.0 0.3 0.4 4.9 0.9 0.2 0.0 1.9 0.0 1.5 2.1 1.5 23.0 6.0 1.3 0.4 0.8 1.7 11.7 0.5 3.2 5.3 0.0 0.1 0.2 82.3 19.7 0.5 0.9 1.0 1.0 0.1 0.4 2.3 YJEFN3 "FLJ44968, hYjeF_N3-19p13.11" ENSG00000250067 "YjeF N-terminal domain containing 3" A6XGL0 19 19528861-19537581 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 50.4;testis: 24.3" "Cell type enriched" "Detected in many" 4 "Late spermatids: 605.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 10.3;HEK 293: 12.1" HPA060789 Enhanced Approved Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 10: Brain - Neuronal signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "HPA060789: AB_2684366" "unprognostic (2.59e-2)" "unprognostic (2.50e-1)" "unprognostic (5.99e-6)" "unprognostic (1.65e-1)" "unprognostic (3.16e-1)" "unprognostic (2.28e-2)" "unprognostic (4.37e-4)" "unprognostic (2.38e-1)" "unprognostic (1.04e-2)" "unprognostic (1.06e-1)" "prognostic favorable (7.25e-4)" "unprognostic (2.11e-2)" "prognostic unfavorable (1.30e-7)" "unprognostic (1.17e-2)" "unprognostic (8.26e-2)" "unprognostic (2.48e-1)" "unprognostic (9.49e-3)" 0.4 0.4 22.1 0.4 46.0 0.0 0.3 0.2 38.9 0.4 1.2 0.6 0.1 0.3 2.7 0.3 0.8 0.1 1.8 50.4 15.3 2.2 0.9 0.4 0.4 10.6 5.4 0.7 0.6 0.1 4.3 0.3 6.1 1.9 0.4 0.5 0.2 0.3 0.5 1.3 0.4 0.2 0.8 0.9 0.6 24.3 6.6 0.2 1.0 0.1 0.3 0.6 0.4 9.7 0.2 0.8 1.7 0.7 0.2 0.4 10.3 0.6 0.1 0.4 0.6 0.8 0.6 0.5 1.4 0.1 0.1 1.1 0.2 0.2 0.0 0.1 12.1 0.0 1.8 0.0 0.1 0.2 0.5 0.1 0.5 0.2 0.4 0.1 0.0 0.7 0.8 0.6 0.0 0.9 0.0 0.1 3.3 0.0 2.5 1.9 0.4 0.3 0.0 0.1 0.2 2.8 0.2 0.0 0.3 0.5 1.2 1.4 0.7 0.3 0.8 3.2 0.8 2.7 2.2 0.6 0.2 1.6 0.3 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.2 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.4 0.0 22.1 46.0 0.2 38.9 50.4 15.3 10.6 5.4 6.1 0.8 6.6 9.7 2.7 9.6 0.5 11.8 2.3 2.0 2.2 1.8 0.6 19.7 3.2 3.2 1.9 1.5 4.4 0.0 10.4 1.6 2.3 6.2 1.9 1.8 136.4 2.6 4.0 2.5 5.4 4.4 22.4 0.6 1.1 2.4 5.6 5.5 1.3 4.0 1.4 1.8 1.1 10.1 29.0 6.7 0.0 0.6 2.0 605.2 3.7 2.0 1.8 5.6 1.4 5.1 3.1 3.5 6.3 0.7 2.6 1.9 0.7 2.4 4.4 0.5 2.3 17.2 6.6 7.5 3.8 16.1 13.2 0.7 4.1 1.8 2.8 0.9 6.0 1.2 YRDC "FLJ23476, IRIP, SUA5" ENSG00000196449 "YrdC N6-threonylcarbamoyltransferase domain containing" Q86U90 1 37802945-37808208 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 50.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 77.8;Prostatic glandular cells: 87.8;Urothelial cells: 92.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "basophil: 8.8" "Lineage enriched" "Detected in many" 8 "granulocytes: 8.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030147 Approved Approved Mitochondria NA NA "Cluster 34: Basophils - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" Mitochondria "HPA030147: AB_10603327" "unprognostic (2.98e-2)" "unprognostic (6.29e-2)" "unprognostic (1.36e-3)" "unprognostic (2.08e-3)" "unprognostic (2.03e-1)" "unprognostic (1.39e-2)" "prognostic unfavorable (1.83e-6)" "unprognostic (5.43e-2)" "unprognostic (5.50e-2)" "unprognostic (1.66e-1)" "unprognostic (2.13e-1)" "unprognostic (2.10e-1)" "unprognostic (4.34e-3)" "unprognostic (3.33e-2)" "unprognostic (1.40e-1)" "unprognostic (1.69e-1)" "unprognostic (1.46e-2)" 12.4 11.1 8.2 9.8 8.2 50.1 11.2 9.5 9.8 6.6 7.9 9.8 8.2 7.5 8.0 16.1 8.0 8.6 7.8 8.2 8.8 10.5 14.1 8.9 10.5 8.3 8.3 7.2 14.1 10.8 10.6 13.3 8.8 8.6 11.9 8.1 9.7 6.0 8.6 16.0 8.6 9.4 7.9 9.2 10.6 16.9 8.8 8.3 9.1 5.7 10.9 16.4 9.7 8.0 25.2 17.6 18.7 23.9 12.7 14.6 53.6 20.3 16.5 31.5 19.9 23.7 23.3 60.3 32.6 20.4 36.1 20.0 35.6 32.8 29.2 36.3 35.1 42.1 21.3 24.9 27.9 55.5 41.7 15.2 48.1 35.0 50.3 20.6 22.5 45.7 66.5 26.4 25.4 17.6 32.7 32.4 70.2 36.3 37.1 32.3 30.1 39.3 26.1 25.2 48.5 49.7 22.0 28.0 72.8 33.2 15.3 24.2 20.9 26.8 28.3 29.6 67.8 53.2 81.2 50.3 23.6 35.4 43.8 8.8 0.6 0.5 0.6 0.6 0.6 0.5 0.9 0.5 0.5 0.8 1.0 1.0 0.7 0.5 0.4 0.9 1.0 0.4 8.2 8.2 9.5 9.8 8.2 8.8 8.3 8.3 8.8 7.9 8.8 8.0 31.3 0.0 9.2 3.9 21.0 50.6 77.8 6.3 29.6 10.8 28.3 25.9 3.6 10.0 5.5 5.5 6.2 24.3 23.6 7.6 23.5 7.7 3.5 16.2 15.7 22.5 15.6 17.2 3.5 9.2 48.5 14.4 10.2 25.4 7.0 13.0 10.8 12.5 12.7 21.9 3.8 10.2 4.1 9.4 19.1 1.8 4.1 15.3 5.4 3.7 6.3 10.9 4.1 3.0 5.0 15.9 7.1 4.1 25.6 87.8 6.1 16.8 4.9 8.8 6.6 12.5 22.0 19.4 37.4 28.6 49.3 40.6 20.2 14.2 11.7 92.7 ZBTB3 FLJ23392 ENSG00000185670 "Zinc finger and BTB domain containing 3" Q9H5J0 11 62748319-62754184 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 12.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035321, HPA035322" Approved Approved Mitochondria NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 5: NTERA-2 - Transcription" "Cluster 29: Early spermatids - Spermatogenesis" Mitochondria "HPA035321: AB_2674569, HPA035322: AB_10610567" "unprognostic (1.39e-1)" "unprognostic (2.08e-2)" "unprognostic (3.48e-2)" "unprognostic (1.83e-3)" "unprognostic (2.93e-1)" "unprognostic (5.52e-3)" "unprognostic (7.85e-2)" "unprognostic (1.37e-1)" "unprognostic (4.56e-2)" "unprognostic (5.02e-2)" "unprognostic (1.23e-2)" "unprognostic (1.83e-1)" "prognostic favorable (1.65e-5)" "prognostic favorable (9.98e-4)" "unprognostic (3.37e-3)" "unprognostic (4.15e-2)" "unprognostic (2.43e-2)" 1.3 1.4 3.2 2.2 4.9 2.3 2.0 3.5 3.9 1.8 1.4 2.4 2.3 1.6 1.9 1.9 4.3 1.0 3.0 2.9 2.6 1.7 1.8 2.8 2.4 4.2 3.7 2.5 2.5 2.2 1.0 2.0 3.9 1.8 2.1 3.1 3.5 2.2 2.8 5.8 2.2 1.8 2.6 2.1 5.0 2.8 3.6 2.8 2.7 3.2 2.6 1.4 1.2 8.1 2.1 3.2 2.6 3.5 4.9 2.4 2.2 2.3 2.4 2.6 2.3 2.1 2.7 3.4 3.3 2.4 1.9 4.6 2.3 2.5 1.2 3.9 3.9 1.8 6.7 2.6 2.4 2.7 3.7 2.7 2.9 2.0 3.0 3.3 2.2 2.7 3.3 3.5 2.6 4.3 3.4 3.1 7.8 1.6 1.6 2.5 2.0 3.3 2.1 2.7 2.4 2.3 2.3 2.9 1.6 3.7 4.3 2.0 2.0 3.9 1.7 2.8 1.3 3.6 2.8 2.9 3.7 1.6 1.5 1.9 7.2 9.4 4.0 5.6 4.8 4.0 4.1 4.9 5.2 3.3 4.6 3.6 2.3 5.0 4.8 1.5 5.9 6.2 3.2 4.9 3.5 3.9 2.9 2.6 4.2 3.7 3.9 2.6 3.6 8.1 1.4 3.2 2.7 0.7 2.1 0.8 1.6 1.3 2.8 2.7 1.6 1.8 3.3 1.5 1.3 0.0 6.2 4.4 0.9 3.2 7.9 3.2 12.8 1.5 2.4 1.7 0.0 0.4 0.5 1.9 2.4 1.9 2.6 1.6 0.0 2.5 1.1 3.0 2.4 0.0 0.5 3.1 4.1 2.2 0.8 7.5 1.5 1.4 0.0 0.0 2.0 1.7 4.1 0.0 2.2 2.1 3.9 3.0 1.0 1.1 2.8 2.7 1.4 4.5 0.0 0.9 1.8 2.9 3.9 1.0 1.1 2.5 1.5 2.1 1.9 1.1 ZDHHC11 "FLJ13153, ZNF399" ENSG00000188818 "Zinc finger DHHC-type containing 11" Q9H8X9 5 795606-850986 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 19.2;Early spermatids: 17.0;Endometrial ciliated cells: 26.2;Excitatory neurons: 21.4;Inhibitory neurons: 16.4;Oligodendrocytes: 18.3;Respiratory ciliated cells: 25.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "T-47d: 11.5" "HPA057886, HPA069008" Uncertain Approved Mitochondria NA NA "Cluster 43: Testis - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 49: Ciliated cells - Cilium organization" Mitochondria "HPA057886: AB_2683548, HPA069008: AB_2686068" "unprognostic (2.67e-1)" "unprognostic (9.76e-3)" "unprognostic (4.47e-5)" "unprognostic (5.43e-2)" "unprognostic (7.46e-2)" "unprognostic (4.68e-2)" "unprognostic (3.71e-2)" "unprognostic (1.49e-2)" "unprognostic (1.01e-2)" "unprognostic (2.32e-1)" "unprognostic (2.28e-2)" "unprognostic (2.65e-1)" "unprognostic (5.23e-5)" "unprognostic (4.80e-2)" "unprognostic (3.98e-1)" "unprognostic (1.86e-2)" "unprognostic (3.51e-2)" 1.9 0.9 8.0 0.4 9.9 0.5 2.1 8.3 13.0 2.7 8.0 3.5 6.1 1.1 1.8 3.9 6.5 0.9 9.0 7.4 5.1 4.1 5.2 4.7 0.5 7.9 9.9 1.7 2.8 0.6 12.0 0.8 9.0 2.8 0.8 4.3 2.7 0.9 2.0 3.1 2.9 0.5 2.3 3.3 4.4 10.4 7.1 0.7 2.4 2.2 0.7 2.4 2.2 15.0 0.4 7.4 4.1 0.9 1.3 0.3 5.4 0.3 0.1 0.2 0.1 1.0 0.3 3.1 0.8 0.0 0.9 7.1 2.6 0.0 0.0 9.6 4.9 0.3 3.0 3.9 0.4 4.5 0.3 0.4 0.3 0.9 1.0 0.3 0.0 1.2 0.7 1.7 0.2 3.5 0.4 2.5 7.3 0.0 2.8 4.6 2.7 4.3 0.2 1.5 4.2 0.8 0.2 0.1 3.5 8.0 11.5 0.8 0.4 0.2 6.9 3.9 0.1 5.6 8.3 0.9 0.3 9.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 9.9 8.3 13.0 7.4 5.1 7.9 9.9 9.0 2.3 7.1 15.0 0.7 19.2 13.1 8.5 0.0 1.9 0.4 0.6 0.0 3.4 1.6 2.0 7.7 1.5 13.4 0.0 0.0 0.2 0.3 1.2 0.0 0.5 17.0 26.2 3.8 1.5 1.8 0.4 21.4 0.0 0.1 3.6 4.1 4.2 3.8 0.1 1.1 2.7 0.4 6.7 16.4 3.9 0.0 0.0 0.3 9.1 0.6 0.9 0.0 0.0 0.1 0.3 0.0 7.5 18.3 0.2 1.7 0.0 1.4 0.3 6.0 1.3 25.8 2.2 6.6 0.9 1.0 9.5 3.7 0.7 1.6 0.3 1.1 0.1 1.6 0.4 ZDHHC11B ENSG00000206077 "Zinc finger DHHC-type containing 11B" P0C7U3 5 710355-784729 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in many" 6 "brain: 29.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 23.0;Excitatory neurons: 47.2;Inhibitory neurons: 38.3;Oligodendrocyte precursor cells: 26.7;Oligodendrocytes: 70.1;Respiratory ciliated cells: 21.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 2.1;SCLC-21H: 2.4;THP-1: 3.4" "HPA057886, HPA069008" Uncertain Approved Mitochondria NA NA "Cluster 65: Brain - Ion transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA057886: AB_2683548, HPA069008: AB_2686068" "unprognostic (2.81e-1)" "unprognostic (8.38e-3)" "unprognostic (3.79e-2)" "unprognostic (5.11e-3)" "unprognostic (7.18e-2)" "unprognostic (4.02e-3)" "unprognostic (1.19e-1)" "prognostic favorable (3.98e-4)" "unprognostic (4.39e-3)" "unprognostic (1.29e-1)" "unprognostic (1.45e-4)" "unprognostic (6.94e-2)" "unprognostic (1.43e-2)" "unprognostic (9.21e-2)" "unprognostic (1.73e-1)" "unprognostic (5.13e-2)" "unprognostic (2.31e-1)" 0.7 1.2 15.1 0.2 19.6 0.0 0.8 5.9 19.9 0.5 0.0 2.0 2.7 0.4 0.1 1.5 2.0 0.3 4.5 14.6 9.0 0.7 1.2 2.4 0.0 14.2 8.6 0.6 1.8 0.4 4.5 0.2 14.9 0.5 2.3 4.3 1.7 0.5 3.6 2.2 2.4 0.4 3.3 1.2 2.3 0.7 15.5 0.0 1.1 1.6 0.3 1.0 0.6 29.5 0.0 0.8 0.0 0.7 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.6 2.1 0.1 0.0 0.3 0.4 0.0 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 2.4 0.4 0.0 0.0 0.7 0.3 0.0 3.4 0.0 0.0 0.6 0.0 0.0 0.8 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 19.6 5.9 19.9 14.6 9.0 14.2 8.6 14.9 3.3 15.5 29.5 0.2 19.2 23.0 17.0 0.0 2.7 1.0 0.1 2.2 7.0 1.1 0.9 8.9 1.5 5.7 3.7 0.0 0.0 0.4 2.0 0.0 0.8 2.5 11.9 0.7 2.8 3.0 0.0 47.2 0.8 0.1 4.7 4.1 3.6 1.3 0.0 0.7 2.3 1.7 10.1 38.3 6.7 0.0 0.6 1.1 0.4 0.9 0.8 0.0 1.9 0.0 0.6 0.0 26.7 70.1 0.1 1.4 0.0 1.7 0.3 7.7 0.5 21.8 0.3 6.6 1.4 2.4 5.0 2.5 2.3 3.1 0.0 1.5 0.5 2.4 2.6 ZNF19 "KOX12, MGC51021" ENSG00000157429 "Zinc finger protein 19" P17023 16 71464555-71565089 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 25.9;Spermatocytes: 15.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" HPA063685 Approved Approved Mitochondria NA NA "Cluster 24: B-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 46: Photoreceptor cells - Phototransduction" Mitochondria "HPA063685: AB_2685090" "unprognostic (5.59e-4)" "unprognostic (1.38e-1)" "unprognostic (1.39e-1)" "unprognostic (2.05e-4)" "unprognostic (6.02e-3)" "unprognostic (4.92e-2)" "unprognostic (3.34e-2)" "unprognostic (6.97e-3)" "unprognostic (2.23e-1)" "unprognostic (4.84e-2)" "unprognostic (8.90e-4)" "unprognostic (1.31e-1)" "unprognostic (3.04e-6)" "unprognostic (3.38e-1)" "unprognostic (1.03e-1)" "unprognostic (2.83e-2)" "unprognostic (4.87e-2)" 3.3 3.2 1.7 2.4 3.1 2.6 3.5 2.5 6.0 2.0 3.1 2.4 3.7 3.9 8.3 4.4 8.3 6.5 4.3 4.3 0.6 3.5 2.3 4.3 3.1 0.4 0.1 4.2 6.2 4.3 5.3 1.8 0.0 3.2 2.1 11.3 3.4 2.0 9.7 6.5 3.1 1.5 0.0 2.7 2.9 16.2 1.6 1.1 8.2 1.7 1.4 1.7 0.6 5.7 1.2 1.0 2.9 2.8 1.3 0.9 2.0 1.9 0.9 1.1 1.2 2.1 3.9 1.7 2.1 0.9 2.0 1.4 1.4 1.7 0.4 1.3 1.3 2.3 2.2 3.2 0.8 2.3 1.9 2.1 1.8 1.5 3.2 2.5 0.5 3.0 1.3 2.1 1.4 1.8 1.6 1.5 1.5 0.7 2.5 1.0 2.5 0.6 1.6 2.2 4.0 3.0 3.3 1.1 2.6 1.9 2.2 1.8 1.0 3.3 1.7 2.1 1.8 1.9 1.9 0.4 2.7 1.3 1.8 2.3 0.9 0.8 1.1 0.8 0.3 2.1 1.2 1.1 0.7 2.4 1.5 1.4 1.7 0.9 1.0 1.3 0.5 0.6 1.7 3.1 2.5 6.0 4.3 0.6 0.4 0.1 0.0 0.0 1.6 5.7 1.4 0.0 3.2 3.9 3.7 0.3 2.0 2.1 1.2 3.8 3.1 1.8 1.2 1.5 2.3 1.8 10.4 1.4 2.3 1.8 5.9 4.4 7.3 6.3 1.3 1.6 1.2 3.6 1.7 1.4 0.8 2.1 0.5 1.2 0.0 5.0 2.2 4.1 1.4 10.1 1.6 2.0 2.0 1.0 1.6 4.4 0.6 0.9 0.0 2.8 1.3 3.5 0.0 2.0 2.1 2.2 1.7 1.9 0.8 1.3 3.6 3.3 10.0 25.9 6.6 2.2 2.0 15.3 7.6 0.8 0.6 0.5 1.8 3.4 1.5 1.0 ZNF200 ENSG00000010539 "Zinc finger protein 200" P98182 16 3222325-3236221 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 17.6" "Cell type enhanced" "Detected in many" "Early spermatids: 51.8;Spermatocytes: 39.0;Spermatogonia: 44.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018981, HPA059310" Uncertain Approved Mitochondria No No "Cluster 2: Granulocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Mitochondria "HPA018981: AB_1859021, HPA059310: AB_2683974" "unprognostic (1.74e-1)" "unprognostic (5.74e-2)" "unprognostic (3.21e-2)" "unprognostic (8.78e-2)" "unprognostic (9.72e-2)" "unprognostic (3.71e-2)" "unprognostic (1.31e-1)" "unprognostic (2.20e-1)" "unprognostic (7.55e-2)" "unprognostic (2.16e-1)" "unprognostic (3.80e-2)" "unprognostic (2.98e-2)" "unprognostic (2.68e-1)" "unprognostic (1.12e-2)" "unprognostic (1.89e-1)" "unprognostic (1.11e-1)" "unprognostic (5.23e-3)" 3.7 3.0 2.2 5.8 2.3 2.4 4.4 3.1 3.3 3.5 2.2 3.4 4.1 3.8 3.7 3.3 4.3 3.5 3.4 2.4 2.5 3.5 3.9 4.0 7.0 2.5 2.3 4.4 2.2 4.7 2.4 6.3 2.3 3.4 3.6 4.0 2.8 3.4 2.1 3.2 3.2 3.9 2.4 6.1 3.3 17.6 2.4 5.2 3.3 3.6 6.6 4.2 2.9 2.4 7.1 7.3 16.1 11.6 5.9 6.1 19.2 9.1 11.2 12.2 11.2 11.2 5.9 13.6 6.8 7.4 7.2 5.3 13.2 9.8 14.6 12.7 12.2 11.3 9.6 9.5 7.8 19.9 26.0 6.2 8.3 9.0 8.1 7.0 10.8 9.7 12.8 10.3 11.1 6.5 14.0 10.8 25.3 8.8 6.9 16.9 22.0 16.0 7.6 4.0 9.1 13.3 8.6 6.5 7.5 11.0 9.3 21.9 7.4 12.4 11.4 4.5 8.0 25.8 27.1 11.9 3.0 12.3 9.8 32.4 5.3 18.4 10.6 6.8 10.3 7.2 9.4 12.5 6.6 6.9 9.6 10.9 22.1 11.6 6.6 4.2 12.1 7.2 2.2 2.3 3.1 3.3 2.4 2.5 2.5 2.3 2.3 2.4 2.4 2.4 10.7 3.2 3.7 4.2 6.4 3.2 4.5 4.2 1.2 5.4 5.2 5.8 3.9 5.7 5.1 3.7 12.5 7.5 7.4 3.3 3.9 5.0 51.8 3.6 3.2 8.1 6.7 9.1 5.2 4.0 6.7 5.0 0.5 3.1 5.1 5.7 10.4 3.8 7.1 0.0 4.1 3.8 4.1 6.6 5.4 22.6 5.6 6.6 7.2 1.9 6.3 6.7 13.4 5.0 3.4 3.6 6.3 3.0 5.7 4.6 3.7 2.8 3.5 8.1 6.6 7.4 4.5 39.0 44.9 4.3 3.1 5.9 8.5 6.1 3.5 4.0 ZNF230 FDZF2 ENSG00000159882 "Zinc finger protein 230" Q9UIE0 19 44002957-44013924 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA006172 Approved Mitochondria No No "Cluster 5: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 43: THP-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Mitochondria "HPA006172: AB_2667532" "unprognostic (3.55e-3)" "unprognostic (5.21e-2)" "unprognostic (2.88e-2)" "unprognostic (1.78e-1)" "unprognostic (2.01e-2)" "unprognostic (4.27e-2)" "unprognostic (5.88e-2)" "unprognostic (3.89e-2)" "unprognostic (3.79e-2)" "unprognostic (1.35e-1)" "unprognostic (4.08e-4)" "unprognostic (2.45e-2)" "unprognostic (1.14e-2)" "unprognostic (8.59e-2)" "unprognostic (1.68e-1)" "unprognostic (4.62e-2)" "unprognostic (1.42e-5)" 2.0 2.1 1.1 2.2 1.3 3.2 3.2 2.8 2.0 2.3 1.5 2.0 1.3 2.3 2.1 1.4 2.5 1.6 1.8 1.1 1.4 1.7 2.1 2.4 3.4 1.2 1.3 4.2 1.4 2.7 2.7 2.4 1.4 2.2 2.0 4.6 1.9 2.5 0.8 2.9 2.4 1.8 1.3 3.9 1.9 1.8 1.3 4.0 3.0 1.9 3.9 2.0 1.7 1.8 2.1 1.7 3.4 3.5 2.7 3.3 1.3 2.9 2.9 2.6 4.7 1.0 1.1 1.7 1.9 2.1 1.6 1.7 2.9 2.6 3.9 2.1 3.6 2.9 4.1 1.2 1.5 3.8 2.4 2.5 2.4 2.9 3.0 3.5 1.8 2.0 0.5 0.0 2.7 1.1 4.3 2.7 2.0 1.4 1.6 3.1 4.7 0.8 1.5 2.4 1.9 4.3 4.1 1.4 2.1 2.3 1.2 8.7 2.3 4.1 3.0 1.2 2.2 2.1 2.2 0.3 2.0 2.8 2.6 6.2 3.3 8.7 3.6 4.0 3.8 4.2 4.1 3.7 3.6 4.2 4.5 4.2 11.5 2.9 2.0 2.2 3.7 2.9 1.1 1.3 2.8 2.0 1.1 1.4 1.2 1.3 1.4 1.3 1.3 1.8 4.7 0.0 2.2 1.6 8.3 2.8 2.6 3.0 4.6 8.5 3.3 3.9 6.0 10.0 3.5 3.7 16.7 4.0 9.9 2.7 3.9 3.0 2.7 2.9 3.3 4.2 1.2 2.1 4.6 2.4 3.2 4.4 2.6 1.7 1.3 4.8 3.9 2.7 3.2 8.4 3.8 2.4 10.2 4.4 3.3 1.7 6.5 3.6 3.6 3.7 7.9 5.4 7.2 2.5 4.0 1.2 0.8 4.5 1.4 2.0 4.1 1.6 2.9 9.6 6.6 3.9 4.3 13.7 7.9 2.8 2.7 3.1 6.7 3.7 3.2 2.0 ZNF467 "EZI, Zfp467" ENSG00000181444 "Zinc finger protein 467" Q7Z7K2 7 149764182-149773588 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 60.2;Distal tubular cells: 39.2;Hepatic stellate cells: 40.7;Kupffer cells: 56.8;monocytes: 37.1;Muller glia cells: 75.3" "Cancer enhanced" "Detected in all" "ovarian cancer: 22.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 48.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 48.6" "Cell line enhanced" "Detected in many" "AN3-CA: 28.8;EFO-21: 13.5;HMC-1: 15.9;MCF7: 12.9;SK-BR-3: 12.7;T-47d: 15.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042907 Uncertain Approved Mitochondria NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 5: Muller glia cells - Visual perception" Mitochondria "HPA042907: AB_10966965" "unprognostic (3.01e-1)" "unprognostic (2.41e-1)" "unprognostic (6.40e-4)" "unprognostic (5.99e-2)" "unprognostic (2.91e-1)" "unprognostic (1.33e-1)" "unprognostic (1.20e-1)" "unprognostic (1.46e-1)" "unprognostic (6.88e-2)" "unprognostic (5.14e-2)" "prognostic favorable (4.56e-4)" "unprognostic (2.12e-1)" "unprognostic (8.15e-2)" "unprognostic (3.19e-1)" "unprognostic (1.51e-1)" "unprognostic (2.53e-2)" "unprognostic (2.25e-2)" 13.2 9.5 7.1 3.8 12.8 10.7 8.9 5.7 7.5 10.1 4.8 10.6 1.0 10.5 1.5 5.5 13.8 3.1 10.7 6.9 6.7 25.5 14.6 16.3 3.7 8.5 8.5 8.5 14.8 5.6 14.5 2.0 7.5 7.4 1.4 11.1 9.3 3.8 1.6 9.3 7.9 2.7 7.0 27.6 16.1 1.5 8.0 4.2 16.1 3.0 2.3 7.0 6.9 5.5 0.0 3.4 4.2 28.8 0.1 0.0 0.1 0.1 0.0 0.4 0.1 1.0 8.6 0.2 13.5 0.2 0.1 0.3 2.2 0.1 0.2 0.1 0.4 1.6 0.0 0.0 8.7 0.0 15.9 5.8 1.2 0.0 0.1 10.9 3.0 0.6 2.5 0.7 0.0 12.9 0.5 1.4 0.4 1.3 8.3 2.3 0.1 10.7 2.1 0.0 1.4 1.2 0.0 12.7 0.0 1.4 15.6 1.3 6.3 0.2 4.4 0.0 0.0 0.6 0.0 0.2 0.2 4.9 0.1 0.0 8.9 4.4 0.3 3.7 0.2 0.0 0.4 0.4 5.8 0.0 0.6 0.2 48.6 0.2 1.2 2.9 0.0 2.4 7.1 12.8 5.7 7.5 6.9 6.7 8.5 8.5 7.5 7.0 8.0 5.5 10.3 0.0 0.5 4.2 1.2 3.6 0.6 1.3 0.6 60.2 13.3 6.9 2.0 2.8 4.1 0.0 2.1 0.4 10.6 0.0 39.2 7.7 0.4 2.6 5.0 23.7 3.0 8.0 0.8 2.9 0.2 3.9 2.6 2.1 0.0 0.3 40.7 7.7 22.3 6.7 2.9 0.0 8.2 56.8 19.4 0.3 1.5 23.0 1.8 2.8 37.1 75.3 6.2 0.5 0.2 1.8 0.0 1.9 1.1 0.8 0.0 8.5 1.7 6.5 0.0 0.6 2.8 1.0 2.9 0.7 7.4 0.4 2.8 0.3 0.0 0.5 ZNF48 "DKFZp762K013, FLJ31751, MGC43952, ZNF553" ENSG00000180035 "Zinc finger protein 48" Q96MX3 16 30378106-30400108 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "REH: 47.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023806 Uncertain Approved Mitochondria No No "Cluster 48: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 14: REH - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA023806: AB_1859335" "unprognostic (5.35e-2)" "unprognostic (7.91e-3)" "unprognostic (2.41e-3)" "unprognostic (2.06e-1)" "unprognostic (5.20e-2)" "unprognostic (1.66e-2)" "unprognostic (2.77e-3)" "unprognostic (4.25e-2)" "unprognostic (6.06e-2)" "unprognostic (2.19e-1)" "prognostic favorable (1.20e-6)" "unprognostic (5.36e-2)" "prognostic favorable (7.50e-5)" "unprognostic (6.35e-2)" "unprognostic (1.19e-1)" "unprognostic (1.04e-1)" "unprognostic (2.45e-3)" 2.9 5.1 7.1 3.4 7.3 2.0 3.2 7.9 8.2 4.5 3.9 8.0 3.7 7.2 2.5 2.8 5.7 2.5 4.4 7.5 6.6 4.2 4.2 3.5 4.5 5.7 6.0 3.2 5.6 6.4 5.1 2.0 5.8 4.6 2.4 3.8 4.2 4.4 5.3 4.2 4.1 4.5 5.3 4.2 4.9 2.4 6.7 8.1 3.5 3.7 3.0 5.5 2.8 7.1 7.7 13.4 32.0 25.2 4.3 3.0 9.8 5.7 9.7 12.1 11.2 6.7 10.0 16.2 10.7 5.3 3.4 6.6 15.7 8.9 6.8 12.0 20.2 7.2 6.9 10.2 5.9 9.6 9.1 2.6 11.0 10.0 6.6 11.4 10.9 14.3 12.6 7.2 5.3 28.1 20.8 11.9 26.4 6.0 5.4 47.7 7.4 20.0 7.4 6.6 25.1 31.6 2.5 16.7 2.5 8.4 11.2 8.9 5.1 7.0 8.1 6.3 6.5 8.6 10.9 14.8 4.0 5.8 1.7 0.0 0.0 0.4 0.9 0.0 0.6 0.3 0.4 0.5 0.1 0.3 0.5 0.6 0.0 0.9 0.0 0.4 0.5 0.1 7.1 7.3 7.9 8.2 7.5 6.6 5.7 6.0 5.8 5.3 6.7 7.1 4.0 3.2 2.2 4.6 6.1 3.1 2.5 1.7 4.0 11.7 4.8 5.1 5.4 14.3 3.9 3.7 8.4 3.7 6.7 4.8 1.9 10.4 0.2 3.7 2.8 5.4 9.6 5.2 4.9 7.4 2.2 2.8 1.5 3.7 17.2 7.5 4.2 3.1 2.7 16.8 5.5 4.0 2.0 1.6 2.6 0.3 2.8 1.7 1.8 2.8 6.9 6.6 3.1 1.0 4.0 7.2 5.4 6.8 2.0 4.3 3.5 4.1 1.0 7.3 0.0 3.0 5.5 3.5 3.3 1.8 5.3 0.3 5.0 3.7 6.1 1.7 ZNF7 "HF.16, KOX4" ENSG00000147789 "Zinc finger protein 7" P17097 8 144827464-144847509 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059090 Approved Approved Mitochondria NA NA "Cluster 42: Non-specific - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" Mitochondria "HPA059090: AB_2683901" "unprognostic (1.11e-1)" "unprognostic (4.47e-3)" "unprognostic (1.93e-1)" "unprognostic (1.36e-2)" "unprognostic (2.52e-1)" "unprognostic (2.97e-1)" "unprognostic (8.42e-3)" "unprognostic (3.15e-1)" "unprognostic (1.66e-1)" "unprognostic (1.33e-2)" "unprognostic (2.68e-1)" "unprognostic (7.95e-2)" "prognostic unfavorable (8.46e-8)" "unprognostic (1.15e-1)" "unprognostic (5.00e-1)" "unprognostic (5.43e-2)" "unprognostic (6.53e-2)" 18.4 14.1 10.4 10.7 11.0 14.4 18.3 18.6 12.8 20.2 10.7 18.2 10.4 18.0 15.2 14.8 17.5 10.5 14.3 10.5 9.8 18.3 15.5 14.5 15.0 11.6 10.8 19.4 17.4 15.3 16.8 14.3 11.1 20.5 12.7 13.9 16.4 13.6 26.6 21.1 17.2 12.7 9.0 21.7 15.2 17.0 11.2 15.9 19.3 17.5 15.6 18.3 17.2 13.4 16.7 22.2 21.4 21.1 17.9 27.2 19.6 17.4 22.0 23.1 19.7 11.4 20.9 23.1 19.9 19.0 12.6 14.2 19.5 25.4 25.1 15.4 16.2 41.3 30.6 13.3 20.7 12.1 18.5 26.1 30.3 18.1 44.2 22.4 14.5 19.2 41.9 16.1 26.0 27.3 33.0 13.1 21.8 22.0 26.6 22.6 19.0 18.4 16.1 22.6 21.0 25.6 38.1 21.6 21.3 20.4 26.1 19.1 16.4 17.3 30.9 13.2 16.9 13.0 9.9 25.0 18.0 15.4 21.7 34.3 10.7 10.9 13.5 10.0 16.9 18.1 15.4 12.0 12.2 17.4 20.1 13.8 10.4 16.6 19.2 9.6 16.3 9.2 10.4 11.0 18.6 12.8 10.5 9.8 11.6 10.8 11.1 9.0 11.2 13.4 11.9 19.2 11.6 6.2 16.4 7.0 18.2 12.7 8.6 34.2 9.1 8.0 11.4 7.2 11.3 3.7 29.2 17.3 16.6 6.6 5.9 14.1 18.4 6.3 10.4 10.6 9.6 15.6 11.3 11.2 12.9 14.7 10.2 7.7 3.8 16.7 15.0 8.2 9.1 28.6 10.7 9.1 6.1 9.0 11.1 4.9 17.7 10.2 8.8 3.7 12.9 20.0 22.6 10.6 11.4 13.7 5.6 15.8 7.8 18.6 12.4 7.1 9.2 30.1 6.6 19.3 10.4 44.1 26.7 9.1 9.2 19.4 16.9 19.8 10.2 13.8 ZNF862 ENSG00000106479 "Zinc finger protein 862" O60290 7 149838375-149867479 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 51.2;Excitatory neurons: 44.0;Inhibitory neurons: 45.2;Microglial cells: 31.9;Oligodendrocyte precursor cells: 46.3;Oligodendrocytes: 58.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA024154 Uncertain Approved Mitochondria NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 51: Non-specific - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA024154: AB_1859469" "unprognostic (1.82e-2)" "unprognostic (2.33e-1)" "unprognostic (3.32e-3)" "unprognostic (1.97e-1)" "unprognostic (8.87e-2)" "unprognostic (4.87e-3)" "unprognostic (4.72e-3)" "unprognostic (2.74e-2)" "unprognostic (6.76e-2)" "unprognostic (2.56e-2)" "unprognostic (2.38e-3)" "unprognostic (4.73e-2)" "unprognostic (5.88e-2)" "unprognostic (4.29e-2)" "unprognostic (8.90e-2)" "unprognostic (1.30e-2)" "prognostic favorable (8.66e-4)" 5.6 7.0 8.1 6.8 8.6 5.6 7.7 8.9 8.4 8.9 13.0 8.6 4.4 7.5 11.7 6.1 9.6 7.2 6.2 7.7 8.4 9.2 7.6 6.4 9.5 8.5 7.6 9.7 11.4 10.9 10.4 3.8 8.2 9.0 6.9 9.9 11.7 7.9 6.5 16.7 8.7 6.5 7.0 10.1 7.8 4.2 8.6 12.3 13.6 6.2 9.2 7.4 6.3 10.8 3.3 3.5 7.8 12.3 8.8 9.5 0.2 6.7 6.8 2.2 3.6 0.4 8.6 1.5 8.6 7.7 3.0 2.2 2.3 3.3 1.6 5.0 3.4 1.5 2.9 0.0 7.9 2.4 1.4 10.7 11.8 2.2 3.4 9.7 5.3 9.1 1.7 6.1 4.0 8.5 2.8 6.2 2.6 6.3 3.5 5.1 1.0 9.2 6.2 2.0 3.1 10.3 5.8 4.2 5.8 3.7 3.2 2.9 9.6 5.5 0.2 12.7 2.5 9.4 5.5 1.5 9.5 6.3 6.4 0.0 1.1 0.7 3.2 2.0 0.8 1.8 1.1 1.6 1.4 0.5 1.3 1.2 0.1 0.8 0.7 1.4 0.9 1.0 8.1 8.6 8.9 8.4 7.7 8.4 8.5 7.6 8.2 7.0 8.6 10.8 2.6 0.0 1.5 51.2 6.4 0.8 0.6 1.8 13.6 5.7 4.4 4.1 4.0 2.8 2.9 7.3 12.5 1.1 1.5 1.6 1.9 1.9 1.3 2.9 2.6 3.2 1.8 3.4 44.0 1.4 0.3 6.0 5.6 3.4 4.5 5.2 1.8 3.0 1.0 10.1 45.2 2.0 2.0 1.0 0.4 1.5 1.5 3.2 0.0 31.9 1.5 2.7 0.0 46.3 58.4 1.3 1.9 2.2 3.3 1.6 2.2 0.9 3.2 6.0 0.0 3.7 2.6 1.3 2.3 7.7 1.3 2.6 9.3 2.7 2.2 0.7 ZNFX1 "FLJ11277, KIAA1404" ENSG00000124201 "Zinc finger NFX1-type containing 1" Q9P2E3 20 49237946-49278426 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+ SV40 Large T+: 132.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046629 Approved Approved Mitochondria No No "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Mitochondria "HPA046629: AB_2616451" "unprognostic (1.03e-1)" "unprognostic (2.80e-1)" "unprognostic (1.15e-1)" "unprognostic (3.21e-2)" "unprognostic (1.21e-1)" "unprognostic (3.58e-1)" "unprognostic (2.62e-2)" "unprognostic (2.55e-1)" "unprognostic (3.85e-2)" "unprognostic (1.49e-1)" "unprognostic (3.13e-2)" "unprognostic (2.09e-1)" "unprognostic (1.50e-1)" "unprognostic (2.79e-1)" "unprognostic (8.71e-3)" "unprognostic (7.40e-2)" "unprognostic (7.86e-2)" 17.1 9.4 9.7 14.3 10.7 28.7 12.4 9.1 9.8 10.1 12.1 11.2 11.0 11.3 9.0 8.1 10.7 14.1 13.2 8.9 9.4 11.8 9.6 18.8 14.2 14.0 11.0 9.9 9.2 13.0 8.5 12.3 10.8 9.7 10.5 8.7 10.3 9.6 15.5 11.8 12.4 13.6 13.3 19.1 11.4 13.4 11.9 13.1 13.8 14.5 13.4 16.5 9.0 11.3 16.3 24.9 5.8 8.2 31.4 24.5 9.8 21.6 50.9 132.7 54.9 28.4 13.2 13.5 27.3 43.5 37.6 30.7 10.8 29.3 45.1 12.8 3.6 16.0 18.1 12.5 27.2 13.0 18.7 26.3 26.9 29.7 22.0 24.3 20.3 8.0 12.4 16.2 33.6 6.8 14.2 8.7 5.6 14.0 20.7 8.9 19.6 3.8 21.8 22.1 5.9 4.3 31.6 61.1 22.4 7.1 15.7 10.8 50.9 64.8 18.3 23.8 21.1 10.7 4.0 7.2 26.0 8.7 14.6 19.3 12.3 20.1 13.5 15.2 12.0 9.4 13.6 13.1 9.1 7.1 12.9 10.0 51.9 9.9 27.1 5.2 11.0 11.5 9.7 10.7 9.1 9.8 8.9 9.4 14.0 11.0 10.8 13.3 11.9 11.3 36.5 41.7 27.2 10.4 25.8 27.8 21.2 14.4 19.4 15.7 13.7 11.2 14.4 10.0 24.8 20.2 10.4 6.1 18.7 28.0 0.0 23.9 37.4 15.9 17.9 38.1 13.1 10.7 12.5 22.7 7.0 28.0 28.5 18.6 27.3 8.1 29.3 13.4 15.1 11.8 11.7 14.2 16.2 26.4 38.0 21.1 22.7 34.2 19.6 15.0 30.2 29.5 17.5 7.1 9.9 32.3 21.8 27.1 9.3 32.8 18.7 6.7 42.8 15.1 0.0 27.8 29.9 42.0 16.3 16.2 21.7 11.4 31.4 10.2 10.4 35.7 ZNHIT3 "Hit1, TRIP3" ENSG00000273611 "Zinc finger HIT-type containing 3" Q15649 17 36486629-36499310 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 222.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060019, HPA078211" Approved Approved Mitochondria NA NA "Cluster 30: Non-specific - Translation" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Mitochondria "HPA060019: AB_2684188, HPA078211: " "unprognostic (5.47e-2)" "unprognostic (1.29e-1)" "unprognostic (8.87e-2)" "unprognostic (1.20e-1)" "unprognostic (3.56e-2)" "unprognostic (1.56e-1)" "unprognostic (4.75e-3)" "unprognostic (6.03e-2)" "unprognostic (6.48e-3)" "unprognostic (2.55e-1)" "unprognostic (1.39e-1)" "unprognostic (1.93e-1)" "unprognostic (2.81e-2)" "unprognostic (1.47e-1)" "unprognostic (2.20e-1)" "unprognostic (1.84e-1)" "unprognostic (6.19e-2)" 27.4 32.4 33.4 17.6 34.9 31.2 32.7 33.6 43.1 26.2 31.3 30.9 24.1 24.6 39.9 30.4 24.0 20.1 27.2 33.9 35.1 35.1 35.9 19.4 39.1 33.5 34.0 31.1 33.1 27.4 24.0 21.0 33.9 26.3 30.5 19.5 26.3 20.0 58.0 30.9 24.1 18.9 35.2 25.5 28.2 50.4 33.4 29.4 28.7 32.4 39.7 30.0 26.5 35.6 39.6 39.0 70.4 55.1 38.6 49.4 38.8 35.8 56.0 53.6 55.2 6.9 55.7 67.3 38.8 18.0 66.8 37.1 25.7 30.8 66.5 35.3 25.7 27.2 41.1 54.3 28.2 73.0 37.7 34.4 69.0 22.1 53.6 60.3 37.1 79.6 48.5 39.8 58.3 36.0 98.3 92.5 50.1 38.0 38.0 33.0 71.2 56.1 67.7 35.2 57.6 42.7 42.7 26.3 73.0 59.5 76.3 72.7 36.4 25.2 42.6 50.9 54.3 41.3 57.6 68.8 54.6 44.3 50.5 15.7 14.5 10.3 15.5 11.3 32.4 22.6 27.1 21.5 20.0 21.6 33.9 27.6 7.9 23.8 26.5 20.0 27.2 17.2 33.4 34.9 33.6 43.1 33.9 35.1 33.5 34.0 33.9 35.2 33.4 35.6 29.0 25.6 27.0 7.5 48.3 46.4 34.1 99.9 38.1 25.4 51.2 75.2 11.8 30.0 47.5 33.1 12.5 93.2 58.1 24.4 88.0 61.1 222.2 37.9 29.9 32.3 43.5 33.9 10.9 51.2 98.5 30.9 21.4 32.3 34.2 48.5 25.4 30.4 67.4 15.2 12.7 33.8 42.7 49.4 36.7 79.1 37.0 34.6 53.4 10.3 66.6 42.5 47.4 12.1 14.7 60.9 36.8 44.4 32.4 47.3 50.6 88.1 33.8 28.3 46.0 36.6 37.5 179.1 71.2 37.2 43.8 77.2 58.3 55.9 44.6 34.0