Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ADAMTS4 "ADAMTS-2, ADMP-1, KIAA0688" ENSG00000158859 "ADAM metallopeptidase with thrombospondin type 1 motif 4" O75173 1 161184302-161199054 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 116.8;ovary: 95.9" "Cell type enhanced" "Detected in many" "Adipocytes: 80.3;Endothelial cells: 115.5;Fibroblasts: 88.8;Oligodendrocytes: 56.0;Sertoli cells: 52.6;Smooth muscle cells: 313.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "plasmacytoid DC: 4.4" "Lineage enriched" "Detected in single" 8 "dendritic cells: 4.4" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 11.8;HUVEC TERT2: 14.4;SH-SY5Y: 7.9;TIME: 12.2;U-138 MG: 7.4;U-251 MG: 10.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025876, HPA051296, HPA068374" Uncertain Supported "Nuclear speckles" "Secreted to extracellular matrix" NA NA 11000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Nuclear speckles" "CAB025876: , HPA051296: AB_2681426, HPA068374: AB_2685978" "unprognostic (2.70e-2)" "unprognostic (8.10e-3)" "unprognostic (3.00e-3)" "unprognostic (2.75e-1)" "unprognostic (9.95e-3)" "unprognostic (1.19e-1)" "unprognostic (1.07e-1)" "prognostic unfavorable (5.00e-4)" "unprognostic (1.20e-2)" "unprognostic (9.59e-3)" "unprognostic (2.48e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (7.27e-7)" "unprognostic (1.10e-2)" "unprognostic (1.04e-1)" "unprognostic (1.44e-3)" "unprognostic (3.13e-2)" 116.8 9.8 6.1 16.3 31.5 0.7 43.4 31.1 19.2 16.4 5.8 18.2 0.8 15.0 0.2 6.2 34.6 14.3 53.6 8.1 15.2 26.0 8.7 50.3 1.6 38.2 29.6 95.9 9.0 2.1 13.0 3.2 31.6 16.9 2.0 1.5 5.2 0.5 13.3 5.0 9.4 10.5 28.3 1.8 22.8 1.8 26.2 1.1 21.3 0.4 0.3 31.8 12.2 48.0 0.0 0.0 0.2 0.1 6.4 4.0 0.6 5.4 0.2 0.5 3.0 0.2 0.2 0.2 4.4 1.7 0.0 0.1 0.0 0.0 1.9 0.1 0.3 0.2 0.5 1.3 0.6 0.0 0.1 4.5 0.0 11.8 0.1 0.0 14.4 0.1 0.2 0.3 0.4 0.1 0.0 0.2 5.3 0.0 0.0 0.1 5.1 0.1 0.0 0.1 0.1 7.9 0.0 0.1 0.1 0.3 0.2 0.5 12.2 7.4 0.1 0.4 10.8 0.2 0.1 0.1 2.2 0.1 0.1 0.5 0.1 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.4 0.2 0.0 4.4 0.2 0.1 6.1 31.5 31.1 19.2 8.1 15.2 38.2 29.6 31.6 28.3 26.2 48.0 80.3 0.0 4.1 0.0 0.2 31.2 3.2 0.0 2.2 2.2 8.6 5.5 5.5 0.0 0.6 0.0 0.0 0.3 0.5 0.2 0.0 0.3 0.0 0.3 13.0 115.5 0.0 0.0 0.4 0.0 0.3 88.8 0.5 0.5 0.0 0.3 43.2 0.9 1.0 3.3 0.1 0.0 0.0 1.0 32.6 0.2 0.3 3.2 35.6 2.8 1.0 0.5 0.0 0.0 56.0 0.0 0.0 1.2 0.7 9.8 0.0 0.1 0.0 1.0 52.6 21.2 313.7 2.7 0.6 2.7 19.0 0.4 3.7 1.6 0.3 7.7 AK6 CINAP ENSG00000085231 "Adenylate kinase 6" Q9Y3D8 5 69350984-69370013 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 185.9;Late spermatids: 275.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005361, HPA070217" Supported Supported "Nuclear speckles,Centrosome,Cytosol" No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear speckles" "Centrosome, Cytosol" "CAB005361: AB_2302969, HPA070217: " "unprognostic (5.47e-2)" "unprognostic (1.54e-2)" "unprognostic (1.48e-1)" "unprognostic (8.58e-2)" "unprognostic (8.73e-2)" "unprognostic (4.09e-2)" "prognostic unfavorable (9.54e-4)" "unprognostic (1.79e-1)" "unprognostic (3.41e-2)" "unprognostic (6.21e-2)" "unprognostic (2.55e-2)" "unprognostic (2.25e-2)" "unprognostic (1.14e-2)" "unprognostic (1.31e-1)" "unprognostic (1.84e-1)" "unprognostic (2.22e-1)" "unprognostic (2.55e-2)" 46.0 58.0 18.7 12.5 19.6 11.6 40.0 20.6 27.1 26.1 19.8 40.8 15.2 32.4 21.6 29.7 29.6 7.7 48.4 19.8 20.3 54.9 46.6 29.5 13.0 19.7 20.1 32.6 35.8 11.6 28.6 12.1 19.5 32.9 12.6 23.2 30.9 8.3 79.8 20.6 30.1 9.5 18.7 28.0 36.4 43.3 19.5 13.3 33.0 23.3 12.5 35.5 28.0 20.7 40.3 18.8 28.0 42.6 43.6 26.3 51.1 59.3 18.6 23.8 30.7 56.0 35.5 82.1 54.9 23.4 62.2 14.0 37.2 23.3 40.0 33.1 15.7 40.7 47.8 44.9 33.0 49.5 17.1 14.0 33.3 23.0 37.0 25.0 14.8 45.8 36.6 29.3 28.6 42.1 50.2 31.4 25.0 17.9 10.5 55.8 34.5 44.5 40.3 31.3 14.4 13.3 28.2 26.4 44.6 21.3 25.1 54.7 29.5 20.4 34.6 41.4 47.6 33.1 74.4 75.3 29.8 69.3 28.9 25.2 16.8 20.1 19.2 22.1 20.3 29.8 22.8 24.9 24.8 26.1 24.5 26.3 2.7 24.1 21.0 29.9 25.8 13.3 18.7 19.6 20.6 27.1 19.8 20.3 19.7 20.1 19.5 18.7 19.5 20.7 51.5 22.4 30.0 14.0 33.9 0.0 95.7 0.0 33.6 19.8 57.3 86.6 55.6 18.6 16.7 23.9 10.4 86.7 27.2 16.8 185.9 75.6 174.9 36.4 34.6 38.6 9.7 29.2 14.8 78.5 95.1 47.3 16.8 30.2 21.5 31.7 30.7 42.5 71.3 20.2 15.4 21.3 0.0 30.6 0.0 275.9 33.5 32.2 0.0 6.5 42.4 58.7 34.0 13.0 17.0 59.1 25.5 32.0 29.4 116.6 48.6 149.8 18.2 29.3 52.6 40.9 50.0 56.5 37.9 24.3 0.0 66.2 27.6 44.7 32.9 88.1 AKAP17A "721P, CCDC133, CXYorf3, DXYS155E, MGC39904, SFRS17A, XE7, XE7Y" ENSG00000197976 "A-kinase anchoring protein 17A" Q02040 X 1591604-1602520 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Theca cells: 131.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.5" "Lineage enriched" "Detected in single" 5 "granulocytes: 4.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043247, HPA051020" Supported Supported "Nuclear speckles,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 29: U-266 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" Cytosol "HPA043247: AB_10964776, HPA051020: AB_2681314" "unprognostic (4.55e-2)" "unprognostic (1.56e-1)" "unprognostic (1.74e-1)" "prognostic favorable (3.40e-4)" "unprognostic (5.38e-2)" "unprognostic (1.59e-2)" "unprognostic (9.73e-3)" "unprognostic (6.25e-2)" "unprognostic (2.09e-1)" "unprognostic (7.91e-3)" "prognostic favorable (2.42e-4)" "unprognostic (1.55e-3)" "prognostic unfavorable (3.52e-7)" "unprognostic (1.86e-2)" "unprognostic (2.71e-1)" "unprognostic (4.03e-2)" "prognostic favorable (1.11e-5)" 35.2 46.9 13.7 33.8 15.0 44.6 37.3 12.3 15.2 45.6 15.1 38.6 30.9 35.2 20.1 38.5 39.5 16.5 34.9 13.0 11.9 39.3 70.1 51.5 36.0 16.4 14.1 73.0 66.4 12.6 46.6 17.3 13.5 50.7 9.9 7.5 41.5 15.9 17.4 35.6 49.4 7.6 12.1 83.0 41.3 31.8 16.3 27.2 62.7 9.2 20.1 32.2 38.0 20.3 23.8 29.8 23.4 26.5 11.3 14.4 57.1 25.1 10.2 19.8 16.6 33.3 21.3 35.5 15.8 12.6 27.9 20.4 14.3 12.6 11.8 29.3 49.2 44.3 32.6 31.3 24.1 17.3 71.3 12.8 22.8 14.8 16.4 23.6 13.8 17.7 28.2 21.8 11.7 15.6 38.5 74.4 35.0 5.5 25.6 28.9 27.9 30.0 13.2 16.3 26.1 38.1 19.7 31.5 31.5 19.2 20.6 31.3 26.9 30.8 14.0 26.9 22.1 93.7 17.0 49.1 12.5 27.7 8.4 4.5 0.5 0.9 0.3 0.2 0.4 0.9 0.4 0.7 0.3 0.5 0.3 0.3 1.9 0.7 0.4 0.8 0.2 0.2 13.7 15.0 12.3 15.2 13.0 11.9 16.4 14.1 13.5 12.1 16.3 20.3 41.2 25.6 25.3 1.3 53.5 44.4 36.1 10.6 36.5 24.1 41.5 29.8 12.0 12.8 19.4 12.9 10.4 25.1 67.0 39.9 13.7 21.2 52.1 29.6 32.7 35.1 22.6 14.5 0.8 15.5 32.4 31.5 39.3 41.1 25.4 49.8 32.2 21.3 22.8 16.8 0.8 38.7 12.2 25.7 54.5 18.9 38.8 37.4 40.9 0.0 38.0 21.5 54.6 2.0 2.7 24.4 35.9 31.6 65.0 41.9 22.6 7.9 14.4 15.4 0.0 28.4 23.2 20.6 27.6 31.7 47.2 72.7 51.1 131.7 28.6 46.2 AKAP8L "HAP95, NAKAP95" ENSG00000011243 "A-kinase anchoring protein 8 like" Q9ULX6 19 15380050-15419141 "Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042485, HPA042546" Enhanced Supported "Nuclear speckles" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 6: Erythroid cells - Oxygen transport" "Nuclear speckles" "HPA042485: AB_2678019, HPA042546: AB_2678046" "unprognostic (9.52e-3)" "unprognostic (5.23e-2)" "prognostic unfavorable (3.49e-4)" "unprognostic (1.08e-2)" "unprognostic (3.25e-1)" "unprognostic (3.53e-2)" "unprognostic (1.38e-2)" "unprognostic (2.87e-2)" "unprognostic (1.08e-1)" "unprognostic (3.57e-2)" "prognostic favorable (8.04e-4)" "unprognostic (1.01e-2)" "prognostic unfavorable (1.08e-7)" "unprognostic (2.77e-1)" "unprognostic (1.07e-1)" "unprognostic (8.80e-2)" "unprognostic (2.34e-3)" 27.2 32.8 25.1 4.0 25.5 32.3 26.9 26.0 32.2 34.8 21.8 32.7 2.5 23.5 11.9 23.4 31.8 7.5 41.5 24.4 25.3 29.3 28.8 33.5 9.4 24.1 24.4 36.2 22.5 11.1 40.4 9.3 24.7 32.3 5.8 37.4 23.2 6.3 60.5 34.5 24.0 6.4 25.0 31.5 24.7 48.8 25.8 20.6 33.9 24.1 10.8 26.8 28.1 26.1 25.4 25.8 32.3 17.2 32.3 34.0 18.8 21.0 25.1 34.0 30.9 41.5 35.2 23.2 38.8 23.4 31.8 29.9 51.2 28.3 29.8 39.8 44.2 40.3 21.9 34.0 57.3 38.8 26.6 29.6 52.0 27.2 35.3 31.3 25.4 38.0 51.3 41.9 21.3 34.3 39.0 32.6 31.9 32.0 41.9 46.6 22.8 25.2 28.7 8.5 37.2 23.5 26.2 28.3 37.5 42.4 20.8 42.2 30.4 20.5 15.4 34.4 36.7 60.1 48.0 49.5 19.2 39.8 23.5 0.1 1.8 1.7 0.9 0.8 1.8 1.7 0.8 1.0 1.5 2.3 1.3 1.2 3.5 0.5 1.0 1.4 2.8 0.8 25.1 25.5 26.0 32.2 24.4 25.3 24.1 24.4 24.7 25.0 25.8 26.1 34.7 6.4 15.9 55.5 39.1 31.6 48.2 22.6 26.2 60.9 34.6 29.3 7.7 17.2 30.0 35.0 77.2 35.6 47.3 22.5 25.4 32.6 34.6 52.7 33.7 29.8 25.6 114.9 59.1 31.8 28.6 26.0 50.0 42.6 13.9 69.6 17.5 17.0 16.3 79.1 45.1 22.0 26.4 18.6 32.8 9.9 26.4 31.3 26.6 19.7 24.0 42.0 30.9 29.7 38.5 32.5 19.9 29.3 38.2 33.2 13.6 17.3 32.1 83.2 26.3 27.8 45.2 83.3 63.9 26.4 39.2 62.4 44.0 60.2 18.3 40.2 AP5Z1 "KIAA0415, SPG48, zeta" ENSG00000242802 "Adaptor related protein complex 5 subunit zeta 1" O43299 7 4775615-4794397 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Protein transport, Transport" "Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 15.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035693 Supported Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear speckles" Nucleoplasm "HPA035693: AB_10960687" "unprognostic (1.64e-1)" "unprognostic (5.22e-2)" "unprognostic (3.01e-3)" "unprognostic (4.24e-2)" "unprognostic (2.43e-3)" "unprognostic (5.19e-1)" "prognostic unfavorable (1.35e-5)" "unprognostic (1.50e-1)" "unprognostic (2.03e-1)" "unprognostic (1.04e-1)" "unprognostic (1.10e-3)" "unprognostic (1.26e-2)" "unprognostic (5.32e-3)" "unprognostic (8.28e-2)" "unprognostic (1.71e-1)" "unprognostic (1.95e-2)" "unprognostic (2.22e-1)" 14.8 18.5 7.0 0.7 7.1 1.5 11.8 7.3 10.0 12.4 5.8 13.2 1.1 13.4 1.0 11.0 11.0 0.8 7.7 6.9 5.7 9.2 9.2 12.9 1.8 8.3 6.5 11.8 9.9 0.7 9.8 1.1 7.4 11.7 0.4 0.6 12.4 0.7 8.5 21.8 15.5 0.4 5.9 22.9 12.0 8.6 7.4 0.9 11.2 0.2 0.6 13.4 10.9 7.3 2.8 4.2 0.7 2.4 1.0 0.9 4.3 1.3 1.9 2.0 1.7 5.2 3.5 1.6 1.8 0.9 5.1 5.4 0.7 0.5 0.6 1.8 3.5 2.4 4.5 4.6 3.0 2.5 5.1 2.2 1.6 1.8 1.3 0.7 0.5 2.2 3.4 1.1 1.2 7.7 0.3 15.0 5.9 0.3 4.3 2.9 2.6 4.8 1.0 4.4 1.7 3.0 1.8 8.7 6.4 0.5 6.4 8.9 3.8 2.3 4.4 6.5 1.7 8.5 7.4 2.3 1.7 5.6 3.6 1.9 2.3 2.9 2.4 2.8 1.4 1.9 1.8 2.4 1.2 1.8 2.5 2.2 2.2 2.4 2.5 2.4 1.8 1.3 7.0 7.1 7.3 10.0 6.9 5.7 8.3 6.5 7.4 5.9 7.4 7.3 12.4 9.6 15.0 7.5 18.2 6.9 2.9 8.8 8.0 10.5 5.7 5.8 4.3 15.7 6.6 11.0 4.2 11.5 20.3 20.1 0.0 14.1 2.2 9.9 10.1 11.6 12.0 5.0 12.4 13.6 7.7 9.9 21.4 16.4 17.1 14.3 12.5 8.1 28.7 18.5 10.7 15.1 10.2 12.3 10.7 1.5 13.4 16.3 14.2 13.1 23.4 8.2 21.6 10.6 12.6 20.6 15.9 10.9 19.8 4.9 14.7 6.8 8.3 9.4 0.0 5.8 9.5 8.1 10.8 7.6 11.1 16.6 15.6 12.6 14.1 3.8 BARD1 ENSG00000138376 "BRCA1 associated RING domain 1" Q99728 2 214725646-214809683 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 68.6;Basal prostatic cells: 62.2;Suprabasal keratinocytes: 74.4;Urothelial cells: 67.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB034106, HPA035354, HPA044864" Enhanced Supported "Nucleoplasm,Nuclear speckles,Cytoplasmic bodies" No Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Nuclear speckles" "Cytoplasmic bodies" "CAB034106: AB_2061237, HPA035354: AB_2674585, HPA044864: AB_2679119" "unprognostic (4.85e-2)" "unprognostic (1.87e-2)" "unprognostic (1.74e-2)" "unprognostic (8.37e-3)" "unprognostic (2.57e-2)" "unprognostic (1.03e-2)" "unprognostic (6.25e-4)" "unprognostic (1.99e-1)" "unprognostic (2.16e-2)" "unprognostic (3.92e-3)" "unprognostic (2.80e-2)" "unprognostic (7.41e-2)" "unprognostic (1.94e-8)" "unprognostic (3.94e-2)" "unprognostic (2.28e-1)" "unprognostic (1.57e-1)" "unprognostic (1.08e-1)" 1.8 0.6 3.0 2.7 4.6 11.4 2.9 2.2 2.7 3.1 0.2 2.9 2.3 3.3 2.6 5.1 1.9 2.0 1.5 2.3 4.1 0.8 1.0 2.5 5.5 3.8 3.2 2.3 1.6 2.3 1.2 2.3 3.9 2.9 3.6 2.0 1.9 3.6 4.2 8.8 2.1 3.9 3.9 2.6 1.9 6.6 4.1 7.0 1.4 2.3 6.6 2.1 3.8 4.2 12.3 8.8 20.2 9.3 2.7 4.0 12.0 17.3 10.6 17.8 21.8 12.0 12.2 12.6 7.6 8.5 9.5 12.7 16.5 10.5 22.7 11.5 6.4 12.5 13.8 8.7 0.9 13.9 12.7 4.7 1.1 15.0 8.1 4.5 6.1 14.7 7.9 36.0 13.7 10.7 27.9 12.5 14.3 7.9 3.7 24.7 19.8 11.2 3.9 14.0 5.8 8.8 15.0 14.7 5.3 10.9 16.3 13.4 4.7 18.0 14.0 11.7 13.6 10.2 12.6 28.0 7.6 11.3 13.4 3.9 2.0 5.8 4.6 4.0 3.2 9.7 5.4 5.5 3.6 8.2 2.4 4.0 0.3 7.3 3.8 6.9 17.1 2.3 3.0 4.6 2.2 2.7 2.3 4.1 3.8 3.2 3.9 3.9 4.1 4.2 12.3 6.4 2.2 14.7 13.0 68.6 62.2 13.0 14.2 3.3 9.9 14.1 17.4 17.2 12.7 9.2 0.0 18.2 11.3 8.2 3.9 8.0 9.2 13.3 11.9 9.6 1.2 34.5 5.5 6.9 16.0 10.0 10.2 18.0 15.2 28.2 10.0 4.2 12.5 1.7 15.4 13.1 8.2 10.1 12.2 5.7 6.2 11.2 3.6 15.9 16.6 4.4 9.2 19.6 31.7 6.5 6.5 10.1 22.0 22.9 3.2 0.7 12.3 6.8 19.7 15.4 16.9 27.6 43.4 28.6 74.4 5.1 13.4 10.5 14.7 67.2 BCAS2 "DAM1, Snt309, SPF27" ENSG00000116752 "BCAS2 pre-mRNA processing factor" O75934 1 114567557-114581629 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 613.4" "Low region specificity" "Detected in all" HPA067881 Supported Supported "Nuclear speckles,Centrosome" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" "Nuclear speckles, Centrosome" "HPA067881: AB_2685915" "unprognostic (6.93e-2)" "unprognostic (1.88e-2)" "unprognostic (8.58e-3)" "unprognostic (4.74e-2)" "unprognostic (2.49e-1)" "unprognostic (2.99e-3)" "prognostic unfavorable (8.23e-7)" "unprognostic (1.16e-1)" "unprognostic (8.51e-3)" "prognostic favorable (7.96e-4)" "unprognostic (1.57e-2)" "prognostic unfavorable (4.27e-4)" "prognostic favorable (6.49e-4)" "unprognostic (2.25e-3)" "unprognostic (1.03e-1)" "prognostic unfavorable (5.24e-4)" "unprognostic (1.87e-1)" 31.9 40.6 32.8 28.0 35.4 76.2 38.2 36.7 45.3 27.1 34.6 31.6 25.5 35.1 49.7 34.1 24.9 31.8 39.3 35.7 38.8 44.6 51.3 26.9 38.5 34.9 37.6 32.5 28.8 41.3 33.1 27.8 37.8 35.6 32.1 40.4 29.6 27.2 56.4 29.8 26.1 27.8 34.7 26.1 28.7 31.8 34.6 32.2 42.4 25.9 36.2 41.5 23.4 37.7 100.0 35.6 70.8 69.9 37.8 43.8 108.8 71.3 57.0 95.6 97.4 50.8 40.6 88.8 93.9 46.9 64.3 47.8 85.5 72.7 133.3 76.7 75.7 45.0 67.2 74.6 68.8 117.8 48.1 39.2 79.4 97.5 121.3 44.2 63.7 95.0 89.6 64.5 80.5 613.4 103.1 87.5 125.6 60.8 80.8 73.9 127.6 62.2 68.1 85.9 93.5 62.2 90.3 70.3 114.3 59.6 62.3 91.0 52.8 58.2 74.7 116.9 138.2 68.5 76.9 143.4 113.4 94.7 223.9 54.4 36.8 65.3 56.0 45.2 78.9 63.3 71.6 70.6 39.7 58.0 73.8 71.9 34.7 75.0 51.0 51.2 77.6 72.8 32.8 35.4 36.7 45.3 35.7 38.8 34.9 37.6 37.8 34.7 34.6 37.7 51.6 28.9 45.4 11.1 110.1 77.9 114.2 155.9 91.0 62.6 36.7 49.1 76.0 27.1 85.4 49.7 37.5 76.6 99.0 26.4 95.9 66.6 30.3 79.0 51.5 46.9 50.0 30.5 16.4 66.8 89.8 60.0 25.0 139.1 99.1 46.0 28.2 31.3 66.9 38.7 15.1 43.1 103.7 34.9 93.3 17.7 39.7 80.8 67.6 12.2 50.6 98.3 55.6 15.1 18.1 51.2 37.9 43.6 176.7 49.8 29.4 103.9 55.6 67.1 39.5 55.5 71.4 80.8 40.6 95.7 63.4 101.2 117.4 64.2 36.0 114.2 BDNF ENSG00000176697 "Brain derived neurotrophic factor" P23560 11 27654893-27722058 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 38.5;Bipolar cells: 13.8;Cardiomyocytes: 9.1;Excitatory neurons: 22.3;Smooth muscle cells: 25.8;Theca cells: 9.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 36.6;BJ hTERT+ SV40 Large T+: 28.0;BJ hTERT+ SV40 Large T+ RasG12V: 20.9;HBF TERT88: 26.5;U-138 MG: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB009564, HPA031440, HPA056104" Enhanced Supported "Nuclear speckles,Mitochondria" "Secreted to blood" NA Yes 16000000 24000 "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles, Mitochondria" "CAB009564: AB_2064213, HPA031440: AB_2673883, HPA056104: AB_2683038" "unprognostic (1.25e-2)" "unprognostic (2.84e-1)" "unprognostic (4.35e-2)" "unprognostic (2.54e-2)" "unprognostic (1.01e-2)" "unprognostic (6.82e-2)" "unprognostic (2.39e-2)" "unprognostic (2.21e-1)" "unprognostic (3.20e-1)" "unprognostic (1.78e-1)" "unprognostic (1.22e-2)" "unprognostic (2.65e-1)" "unprognostic (3.22e-2)" "unprognostic (3.88e-2)" "unprognostic (5.88e-2)" "unprognostic (1.40e-1)" "unprognostic (2.84e-3)" 0.4 0.5 1.9 0.2 2.4 0.2 0.2 3.3 5.3 0.6 0.1 0.4 0.3 0.2 3.3 0.6 0.1 0.7 3.6 8.2 1.9 0.6 0.1 2.0 0.1 3.3 2.1 0.5 0.4 0.0 1.2 1.6 2.5 2.0 0.1 0.7 0.3 1.8 0.4 0.9 0.1 0.1 0.4 0.1 0.3 0.6 1.6 0.3 1.0 0.0 0.1 2.1 0.6 0.8 2.9 12.2 0.3 0.0 3.7 2.2 0.0 36.6 7.9 28.0 20.9 0.1 4.0 0.0 3.7 11.8 0.5 1.4 0.1 0.2 26.5 0.2 0.1 0.0 3.5 0.0 17.4 0.2 0.2 9.2 4.2 6.8 3.7 18.1 1.3 0.1 0.0 0.1 4.8 0.0 0.0 0.0 4.0 0.1 2.9 0.0 2.0 0.0 4.5 0.0 0.2 1.1 7.8 0.1 0.1 1.7 0.2 0.0 11.0 37.6 6.9 14.4 9.2 0.5 0.1 0.0 14.1 1.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.4 3.3 5.3 8.2 1.9 3.3 2.1 2.5 0.4 1.6 0.8 0.2 38.5 0.5 1.6 0.0 0.6 0.4 0.5 1.8 13.8 0.5 0.9 9.1 0.0 0.4 1.8 4.2 0.4 0.0 0.1 0.0 0.8 1.8 0.3 0.3 0.2 0.0 0.0 22.3 0.0 0.5 6.1 0.0 0.1 1.3 1.9 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.4 1.5 0.3 0.9 1.8 0.0 0.0 0.2 0.0 2.0 2.2 0.2 0.0 0.0 0.0 0.8 0.0 1.5 0.1 1.8 0.0 1.8 25.8 3.7 0.8 2.3 0.0 0.7 0.0 9.3 0.1 0.1 BMP2K "BIKe, DKFZp434K0614" ENSG00000138756 "BMP2 inducible kinase" Q9NSY1 4 78776342-78916365 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 242.9;granulocytes: 129.2;Hofbauer cells: 140.4;Microglial cells: 351.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "fHDF/TERT166: 50.1;HEL: 73.6;HMC-1: 80.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026436, HPA026451, HPA026501" Approved Supported "Nuclear speckles" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Nuclear speckles" "HPA026436: AB_10600102, HPA026451: AB_10600228, HPA026501: AB_10601341" "unprognostic (7.96e-2)" "unprognostic (3.68e-1)" "prognostic favorable (1.74e-4)" "unprognostic (9.08e-2)" "unprognostic (1.97e-1)" "unprognostic (9.73e-3)" "unprognostic (1.51e-2)" "unprognostic (1.47e-1)" "unprognostic (2.98e-1)" "unprognostic (7.60e-2)" "unprognostic (1.39e-1)" "unprognostic (9.60e-2)" "unprognostic (9.90e-2)" "unprognostic (9.45e-2)" "unprognostic (1.59e-1)" "unprognostic (1.55e-2)" "unprognostic (3.18e-2)" 6.0 4.2 8.5 13.5 8.2 11.9 7.4 7.3 7.2 6.5 3.8 9.5 5.6 4.4 5.4 7.4 6.0 7.4 8.0 7.2 18.6 4.9 6.7 7.7 16.5 12.1 11.2 3.1 3.5 4.3 0.6 9.2 13.5 3.3 11.9 6.5 3.5 3.5 2.2 9.9 6.9 6.6 10.9 12.2 4.7 10.2 9.8 10.9 7.7 4.5 16.3 7.1 1.4 16.5 11.4 3.2 6.0 7.5 12.0 11.1 4.8 10.8 14.4 10.3 13.7 6.4 6.4 13.2 5.6 50.1 9.9 2.9 6.7 8.5 19.4 3.5 2.3 73.6 5.0 3.5 13.2 15.9 80.6 15.9 11.0 16.4 15.6 7.3 14.4 10.0 19.8 36.5 12.1 2.4 9.5 7.4 2.9 8.8 2.1 13.5 10.3 3.7 13.3 5.2 8.4 5.2 14.2 7.8 10.4 7.9 2.7 10.0 14.7 10.6 4.2 18.4 11.9 7.7 3.2 4.8 9.9 21.4 7.7 0.1 0.5 0.3 0.0 0.2 0.0 0.6 0.0 0.0 0.4 0.6 0.1 0.0 0.9 0.1 0.8 0.3 0.0 0.1 8.5 8.2 7.3 7.2 7.2 18.6 12.1 11.2 13.5 10.9 9.8 16.5 10.7 28.9 16.2 242.9 31.5 25.0 4.3 5.4 10.2 10.9 27.4 15.2 6.5 2.8 7.7 7.3 4.2 5.0 6.1 24.6 0.0 7.5 15.9 18.6 12.7 17.6 6.7 105.4 53.2 8.8 14.2 13.7 6.6 25.0 129.2 32.1 22.1 19.7 140.4 10.1 59.0 48.2 6.1 65.9 68.2 11.1 8.1 65.4 28.4 351.3 34.6 37.0 1.0 49.3 59.1 14.6 43.0 6.8 7.6 6.3 19.9 18.0 12.3 8.4 6.6 22.3 11.7 26.1 11.2 17.1 31.4 3.4 7.6 5.4 24.0 3.2 BNIP3L "BNIP3a, Nix" ENSG00000104765 "BCL2 interacting protein 3 like" O60238 8 26383054-26505636 "Cancer-related genes, Predicted membrane proteins, Transporters" "Apoptosis, Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 913.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015652, CAB025371" Enhanced Supported "Nuclear speckles,Mitochondria" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 6: Erythroid cells - Oxygen transport" Mitochondria "Nuclear speckles" "CAB025371: , HPA015652: AB_1845406" "unprognostic (1.02e-1)" "unprognostic (2.90e-1)" "unprognostic (2.00e-1)" "unprognostic (8.36e-2)" "unprognostic (6.24e-2)" "unprognostic (1.63e-1)" "unprognostic (1.64e-3)" "unprognostic (1.46e-2)" "unprognostic (5.04e-2)" "unprognostic (2.02e-1)" "unprognostic (2.06e-2)" "unprognostic (2.97e-2)" "prognostic unfavorable (5.92e-5)" "unprognostic (8.72e-3)" "unprognostic (5.16e-2)" "prognostic unfavorable (3.95e-4)" "unprognostic (7.59e-3)" 130.6 53.4 42.7 37.2 60.4 192.6 77.9 55.6 62.0 63.9 38.9 39.6 22.2 52.8 66.3 48.3 50.5 54.7 63.2 50.0 49.6 79.4 45.4 62.9 39.4 60.7 54.0 119.7 20.1 55.1 25.4 104.5 58.4 44.4 28.2 146.5 44.1 64.4 38.9 71.5 28.4 51.3 46.6 40.7 28.9 68.6 48.8 39.9 41.9 31.7 52.1 48.9 49.5 80.8 90.6 33.8 79.1 53.9 214.5 134.0 66.8 89.0 259.9 81.9 179.6 15.3 42.7 27.7 82.5 169.0 113.4 44.8 39.6 114.5 270.0 17.8 21.8 114.9 32.0 26.9 119.3 10.3 191.1 162.5 89.2 92.9 55.3 269.2 106.2 66.9 52.6 65.0 173.7 39.1 72.7 38.5 26.2 56.7 36.6 38.4 99.9 55.6 85.3 58.3 83.9 74.4 43.2 8.8 70.0 85.9 43.7 21.7 140.4 152.2 64.6 96.2 20.5 93.2 46.0 36.8 232.6 20.6 35.1 334.9 298.3 182.9 39.5 154.8 34.9 68.4 58.4 43.3 166.9 78.0 89.3 65.5 369.0 47.6 104.1 38.0 86.1 239.3 42.7 60.4 55.6 62.0 50.0 49.6 60.7 54.0 58.4 46.6 48.8 80.8 118.3 86.6 157.4 28.7 72.2 98.8 56.0 231.7 82.6 142.5 90.6 85.3 34.0 50.1 126.4 103.0 33.3 33.2 55.6 32.7 49.0 115.4 194.1 173.5 140.8 101.2 120.6 913.9 50.6 39.1 166.5 179.9 38.7 341.2 120.9 96.5 167.0 32.2 132.1 82.4 39.4 46.8 118.0 221.3 300.4 206.7 320.3 233.6 106.7 30.0 165.0 406.4 32.0 29.1 75.8 154.1 39.8 347.5 64.6 83.6 44.0 306.4 107.6 64.0 144.7 59.1 183.9 154.4 110.7 65.4 126.6 162.5 67.0 117.6 27.6 79.3 BRD1 "BRL, BRPF2" ENSG00000100425 "Bromodomain containing 1" O95696 22 49773283-49827512 "Predicted intracellular proteins" "Erythrocyte maturation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 76.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000807, HPA001063" Enhanced Supported "Nuclear speckles" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 14: REH - Unknown function" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles" "HPA000807: AB_1078298, HPA001063: AB_1078297" "unprognostic (1.96e-1)" "unprognostic (2.99e-2)" "unprognostic (1.07e-1)" "unprognostic (5.11e-3)" "unprognostic (1.07e-1)" "unprognostic (2.47e-2)" "unprognostic (2.18e-2)" "unprognostic (9.98e-2)" "unprognostic (2.73e-2)" "unprognostic (3.28e-2)" "unprognostic (2.02e-3)" "unprognostic (1.64e-3)" "unprognostic (5.87e-2)" "unprognostic (7.50e-2)" "unprognostic (1.06e-1)" "unprognostic (1.26e-1)" "unprognostic (3.95e-3)" 11.4 7.3 3.1 8.1 3.0 15.0 10.8 12.0 5.0 12.5 3.6 14.7 11.7 15.8 2.8 12.8 13.7 7.7 7.5 3.4 3.2 5.4 6.9 10.0 9.4 3.2 2.8 16.0 13.2 8.5 11.2 8.3 2.9 8.7 5.8 6.1 12.1 8.0 16.7 23.2 12.0 6.7 1.5 12.0 11.5 30.7 3.2 14.0 10.2 8.9 7.6 11.8 12.3 4.5 12.7 12.7 22.8 12.8 9.2 8.2 19.3 13.7 9.3 14.2 11.1 19.3 8.3 13.3 7.9 11.4 5.2 17.9 14.7 9.8 6.1 13.4 26.6 13.2 20.3 11.8 17.8 30.5 18.2 12.2 15.1 8.3 10.5 10.3 10.4 15.9 15.3 14.3 7.3 20.8 23.0 15.9 15.7 9.4 10.1 33.6 19.9 13.9 5.5 18.2 14.6 25.8 17.6 22.7 18.4 10.5 10.6 24.9 12.9 13.1 14.1 9.9 12.7 16.8 4.3 18.9 9.3 10.7 11.8 0.3 0.6 0.7 0.5 0.2 1.0 0.4 0.8 1.0 0.4 0.7 0.8 1.0 0.6 0.8 2.9 0.9 0.3 0.5 3.1 3.0 12.0 5.0 3.4 3.2 3.2 2.8 2.9 1.5 3.2 4.5 25.9 22.4 27.6 16.3 13.8 15.8 5.7 7.1 8.6 26.6 14.0 14.7 8.4 5.7 12.7 3.7 29.2 6.7 76.8 13.3 0.0 6.7 7.5 32.4 37.1 13.9 16.2 8.2 25.3 9.3 6.6 17.2 14.8 47.7 10.1 28.3 14.3 12.3 6.7 33.7 22.2 13.9 4.1 13.3 14.0 6.7 11.8 15.4 12.4 16.9 11.2 13.8 7.2 19.1 21.9 9.5 8.7 13.9 43.1 9.1 10.6 3.2 11.3 36.1 0.0 25.4 20.1 42.6 19.7 10.7 18.5 10.1 40.6 26.4 11.3 9.0 CACTIN "C19orf29, fSAPc, NY-REN-24" ENSG00000105298 "Cactin, spliceosome C complex subunit" Q8WUQ7 19 3610645-3626815 "Predicted intracellular proteins" "Immunity, Innate immunity, mRNA processing, mRNA splicing" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042504, HPA042548" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Nuclear speckles" Cytosol "HPA042504: AB_10797501, HPA042548: AB_10794760" "unprognostic (1.18e-1)" "unprognostic (7.90e-3)" "unprognostic (1.09e-1)" "prognostic favorable (3.69e-5)" "unprognostic (5.93e-2)" "unprognostic (2.87e-3)" "unprognostic (3.38e-2)" "unprognostic (1.01e-2)" "unprognostic (3.84e-2)" "unprognostic (1.38e-2)" "unprognostic (1.17e-2)" "unprognostic (7.22e-3)" "unprognostic (3.88e-2)" "unprognostic (4.98e-3)" "unprognostic (5.78e-2)" "unprognostic (3.08e-2)" "unprognostic (5.55e-3)" 14.6 14.2 20.6 7.8 19.6 10.0 14.8 19.4 24.0 15.7 16.6 15.4 6.2 16.7 2.6 15.4 16.8 3.0 16.3 20.3 18.8 17.0 19.9 12.3 7.6 21.1 19.6 24.7 17.3 4.2 13.3 4.6 19.1 17.2 3.2 4.6 13.2 4.2 19.4 17.8 15.2 2.9 18.5 18.4 15.8 18.2 19.8 8.7 15.3 6.1 4.4 16.5 14.6 20.1 22.2 12.5 10.3 17.9 7.4 7.2 15.6 15.4 6.3 9.1 10.2 12.5 9.7 18.4 12.9 9.7 10.6 20.4 10.8 12.9 5.5 18.7 14.8 11.4 19.2 15.1 10.3 15.7 15.9 7.1 12.2 8.4 5.8 5.4 13.2 15.6 25.9 19.8 4.9 13.3 28.0 13.5 22.0 13.4 14.8 29.4 13.5 17.5 8.5 11.0 14.2 19.9 17.4 12.1 13.3 5.5 9.8 17.7 17.2 12.3 15.5 27.0 27.4 30.3 21.6 20.7 15.2 24.8 16.8 0.0 0.4 0.0 1.2 1.0 0.4 0.6 0.5 0.5 0.3 0.6 0.6 0.8 0.2 0.3 0.1 1.4 0.5 0.4 20.6 19.6 19.4 24.0 20.3 18.8 21.1 19.6 19.1 18.5 19.8 20.1 7.4 0.0 2.7 5.9 6.3 6.0 4.1 2.8 5.7 5.1 6.9 7.1 3.1 5.7 2.2 1.8 2.1 3.6 7.2 6.9 0.0 5.1 3.3 6.7 5.8 5.3 1.2 7.4 3.9 4.9 5.2 5.1 9.2 7.4 4.5 8.5 3.3 4.8 5.1 0.0 4.1 5.8 2.0 3.9 6.5 4.5 5.9 5.3 1.8 3.7 6.1 6.0 8.2 2.5 5.8 5.2 4.4 5.7 6.0 6.0 3.6 3.1 2.4 6.2 0.0 7.2 6.4 10.8 8.8 7.9 8.0 3.3 5.6 7.6 6.1 3.6 CBLL1 "FLJ23109, HAKAI, RNF188" ENSG00000105879 "Cbl proto-oncogene like 1" Q75N03 7 107743949-107761667 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021773, HPA026699" Enhanced Supported "Nuclear speckles" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nuclear speckles" "HPA021773: AB_1846103, HPA026699: AB_1846104" "unprognostic (1.90e-2)" "unprognostic (2.25e-1)" "unprognostic (8.57e-2)" "unprognostic (3.79e-2)" "unprognostic (8.16e-2)" "unprognostic (7.20e-2)" "unprognostic (1.37e-2)" "unprognostic (3.96e-3)" "unprognostic (4.28e-2)" "unprognostic (2.16e-3)" "unprognostic (1.29e-1)" "unprognostic (1.31e-1)" "unprognostic (2.12e-3)" "unprognostic (9.12e-2)" "unprognostic (2.07e-1)" "unprognostic (1.09e-1)" "unprognostic (8.71e-2)" 11.2 8.1 3.1 12.5 5.3 40.0 15.1 7.8 9.5 12.0 3.0 11.3 9.5 13.5 8.4 11.3 11.2 8.7 10.4 4.2 5.8 10.0 11.2 10.3 16.1 4.1 3.7 14.3 11.7 14.1 5.1 12.0 4.1 16.5 11.1 14.4 8.9 12.7 29.0 10.7 10.3 13.4 3.0 14.2 9.2 19.7 3.7 20.2 13.8 21.0 17.8 11.9 7.2 6.6 27.8 31.1 23.7 30.7 21.7 18.6 16.2 20.5 21.6 22.8 22.5 21.4 27.9 40.6 28.5 23.5 37.6 19.3 33.4 25.0 31.0 28.4 21.1 32.5 23.0 18.2 24.9 49.1 30.9 19.6 22.7 30.7 33.0 17.6 23.8 27.8 53.0 33.3 22.4 48.0 66.5 34.4 34.4 23.3 21.3 30.6 25.4 42.0 17.4 25.5 25.4 39.6 30.7 44.9 23.4 27.7 15.1 24.7 23.4 35.0 25.0 33.4 32.0 53.0 62.3 64.1 21.3 29.8 30.3 88.8 31.1 53.3 39.5 32.0 58.2 39.0 61.9 45.8 36.9 39.8 41.8 40.0 48.9 55.1 38.0 20.1 92.6 48.4 3.1 5.3 7.8 9.5 4.2 5.8 4.1 3.7 4.1 3.0 3.7 6.6 18.2 19.2 11.0 6.5 29.6 23.6 16.7 10.5 27.3 12.2 15.9 13.7 16.4 17.2 10.7 3.7 4.2 10.3 27.6 9.9 7.9 9.7 12.4 15.6 19.8 13.5 16.8 39.1 13.9 10.8 9.5 12.6 10.7 13.7 13.3 16.6 12.5 11.0 10.7 10.1 13.1 8.0 8.2 23.3 12.4 5.4 9.3 15.1 19.6 15.9 15.0 7.6 25.7 10.1 20.5 10.1 15.0 11.7 17.3 16.2 8.5 11.2 8.9 14.4 19.7 13.2 14.5 27.2 14.3 19.5 19.9 10.3 27.3 9.5 10.0 18.4 CDC34 "E2-CDC34, UBC3, UBE2R1" ENSG00000099804 "Cell division cycle 34, ubiqiutin conjugating enzyme" P49427 19 531760-542092 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 249.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002382, CAB005109, CAB047311, HPA074334" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nuclear speckles" Cytosol "CAB005109: AB_2276050, CAB047311: , HPA002382: AB_1846370, HPA074334: " "unprognostic (4.65e-2)" "unprognostic (2.02e-1)" "unprognostic (1.41e-1)" "unprognostic (8.72e-2)" "unprognostic (2.84e-1)" "unprognostic (5.73e-2)" "prognostic unfavorable (7.57e-4)" "unprognostic (2.20e-1)" "unprognostic (3.11e-1)" "unprognostic (3.83e-2)" "unprognostic (2.09e-2)" "unprognostic (3.06e-2)" "unprognostic (3.02e-2)" "unprognostic (8.87e-3)" "unprognostic (9.68e-2)" "unprognostic (7.82e-3)" "unprognostic (3.33e-2)" 35.1 36.7 52.0 13.3 51.2 34.5 34.2 51.5 63.0 36.9 47.5 62.5 17.8 33.5 14.1 40.5 33.6 10.1 80.0 52.7 48.7 32.1 88.0 32.1 12.5 51.0 50.7 35.6 58.5 18.7 43.4 29.2 50.8 36.9 11.5 28.2 34.2 19.3 105.0 51.8 27.6 18.5 48.2 31.0 38.6 100.2 52.7 16.4 26.7 63.2 9.7 43.7 34.2 52.7 54.8 54.6 66.4 54.7 29.2 28.4 68.5 47.8 36.1 50.2 51.9 86.1 32.8 29.5 49.3 34.1 30.1 36.9 52.1 40.2 25.0 49.2 146.0 27.8 35.5 94.5 73.6 39.0 32.4 36.4 58.9 42.2 43.6 38.8 60.6 41.2 120.3 57.5 33.8 80.7 53.3 53.6 85.3 39.4 51.7 49.1 35.1 51.2 38.0 32.4 87.2 65.9 41.5 42.1 85.2 53.2 34.0 57.4 50.5 36.5 43.7 86.2 65.2 57.7 47.3 40.1 50.0 55.6 38.8 3.2 2.5 4.7 1.6 2.7 1.1 2.3 2.1 2.9 2.0 1.0 1.6 1.6 8.2 1.2 3.5 1.6 2.5 1.0 52.0 51.2 51.5 63.0 52.7 48.7 51.0 50.7 50.8 48.2 52.7 52.7 39.4 0.0 5.4 21.9 11.4 46.8 17.5 5.4 16.5 35.5 43.4 47.1 27.7 27.1 3.5 14.7 25.0 44.3 30.9 47.4 13.7 24.9 63.9 29.6 28.3 27.7 13.2 77.7 8.3 20.5 55.4 21.4 16.8 42.3 0.0 28.1 15.7 41.1 27.9 16.8 6.3 34.0 14.2 14.5 38.6 249.4 18.0 20.6 19.6 2.8 15.1 68.9 20.6 6.6 12.9 45.0 27.0 15.1 25.0 34.8 25.9 18.9 5.5 44.3 13.1 22.6 34.9 22.4 54.6 15.2 54.7 63.1 22.0 27.1 23.7 27.9 CDK11A "CDC2L2, CDC2L3, CDK11-p110, CDK11-p46, CDK11-p58, p58GTA, PITSLRE" ENSG00000008128 "Cyclin dependent kinase 11A" Q9UQ88 1 1702379-1724357 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 124.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 85.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB010467, HPA025061, HPA073626" Supported Supported "Nuclear speckles,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 11: Alveolar cells - Smell perception" "Nuclear speckles" Cytosol "CAB010467: AB_631212, HPA025061: AB_1846407, HPA073626: AB_2686619" "unprognostic (6.25e-2)" "unprognostic (8.32e-2)" "unprognostic (1.47e-2)" "unprognostic (2.74e-1)" "unprognostic (9.32e-3)" "unprognostic (3.54e-2)" "unprognostic (2.25e-3)" "unprognostic (7.97e-2)" "prognostic unfavorable (5.06e-4)" "unprognostic (1.28e-1)" "unprognostic (5.58e-3)" "unprognostic (3.07e-2)" "prognostic unfavorable (1.15e-6)" "unprognostic (1.97e-1)" "unprognostic (5.98e-2)" "unprognostic (1.54e-1)" "unprognostic (3.70e-2)" 17.7 17.0 14.9 24.8 15.3 41.7 17.7 18.7 16.2 22.2 14.9 25.0 29.3 19.4 8.8 15.7 20.6 9.4 13.5 14.3 15.8 15.5 18.6 27.4 23.3 15.9 14.6 20.3 17.2 9.3 18.5 12.5 15.4 20.3 14.7 13.1 16.8 7.8 26.0 19.8 36.7 8.8 12.9 36.7 20.3 21.6 15.1 17.0 20.0 7.6 13.8 17.8 19.1 16.4 26.6 16.3 18.7 16.9 20.5 14.5 13.4 25.4 14.3 18.7 20.1 21.9 30.1 31.8 15.2 10.0 19.8 27.1 14.3 15.0 14.3 25.4 19.4 28.8 42.6 20.4 13.3 29.6 45.9 17.1 10.7 13.5 12.2 20.3 22.2 21.4 35.7 27.4 11.1 15.5 19.0 33.4 18.1 18.4 16.0 27.7 19.0 18.9 12.3 13.0 17.7 22.6 25.0 36.3 37.9 7.6 20.4 19.4 22.7 24.3 18.5 10.9 17.2 38.0 31.1 35.3 9.8 33.1 7.2 64.1 16.7 22.0 14.5 9.0 12.1 19.3 12.4 10.7 5.6 19.5 12.0 9.9 85.3 12.0 11.6 33.3 10.9 3.5 14.9 15.3 18.7 16.2 14.3 15.8 15.9 14.6 15.4 12.9 15.1 16.4 27.7 51.3 59.0 5.9 33.9 14.0 16.0 12.5 22.2 33.0 11.3 10.4 1.0 14.3 38.3 14.7 27.1 16.2 54.1 28.8 9.8 19.7 37.6 18.0 24.2 26.4 9.1 29.0 5.3 15.3 22.6 16.6 52.5 21.8 84.6 18.9 18.5 15.6 12.2 40.4 5.0 29.1 12.2 12.2 26.9 16.3 35.4 28.5 10.6 2.8 25.6 16.1 44.3 4.5 8.7 25.9 51.0 21.4 42.7 16.3 62.0 11.7 34.5 42.4 13.1 21.3 19.1 124.0 93.7 15.3 14.6 30.5 48.1 16.5 23.0 14.3 CDK13 "CDC2L, CDC2L5, CHED, KIAA1791" ENSG00000065883 "Cyclin dependent kinase 13" Q14004 7 39950121-40099580 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 179.0;Oligodendrocyte precursor cells: 171.9;Oligodendrocytes: 199.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059241 Uncertain Supported "Nuclear speckles,Golgi apparatus,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 34: Non-specific - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "Golgi apparatus, Cytosol" "HPA059241: AB_2683956" "unprognostic (1.99e-1)" "unprognostic (1.22e-2)" "unprognostic (2.67e-1)" "unprognostic (2.72e-1)" "unprognostic (1.83e-1)" "unprognostic (1.02e-1)" "unprognostic (4.18e-3)" "unprognostic (3.42e-2)" "unprognostic (8.09e-2)" "unprognostic (1.13e-2)" "unprognostic (3.77e-2)" "unprognostic (8.13e-2)" "unprognostic (8.20e-2)" "unprognostic (1.21e-1)" "unprognostic (3.33e-2)" "unprognostic (3.53e-1)" "unprognostic (3.53e-2)" 11.4 10.2 8.8 14.6 10.8 28.1 11.1 19.3 9.9 12.8 6.7 11.9 10.5 13.6 14.2 14.7 15.0 12.7 10.4 8.1 10.7 12.7 15.9 12.1 21.7 10.5 8.5 20.1 12.8 17.2 8.0 13.6 8.6 11.2 13.6 19.7 12.9 11.8 11.2 12.0 12.0 12.0 7.2 16.6 12.3 19.0 10.1 19.6 20.6 14.0 20.2 13.4 10.0 14.9 28.4 16.6 28.2 27.0 24.9 24.1 19.3 22.1 23.8 19.8 24.6 17.8 19.1 51.0 12.6 23.4 34.8 33.6 23.4 19.4 29.0 25.3 17.3 22.8 20.0 16.0 23.7 34.8 23.5 14.3 25.5 22.6 30.0 22.6 23.6 23.1 39.0 34.3 20.7 14.7 28.0 24.9 40.8 20.0 19.1 30.5 18.5 20.5 18.5 28.1 20.0 28.8 27.6 59.8 19.9 36.7 24.6 43.0 28.3 27.0 26.0 17.6 30.5 28.3 26.0 41.2 19.8 30.9 35.4 7.8 2.2 4.0 4.1 1.9 2.8 6.4 3.8 3.0 1.3 10.5 3.8 3.9 5.9 4.3 3.1 3.3 3.9 1.3 8.8 10.8 19.3 9.9 8.1 10.7 10.5 8.5 8.6 7.2 10.1 14.9 47.6 44.8 72.0 131.6 49.7 21.4 18.5 15.9 29.0 47.8 36.7 27.7 30.9 25.8 37.1 31.3 70.9 13.7 91.0 23.1 7.9 20.4 13.9 54.3 51.4 30.9 18.7 5.9 179.0 15.4 9.1 31.7 30.1 72.6 17.1 95.5 19.2 23.7 13.2 37.0 166.2 17.6 14.2 23.8 17.4 9.2 26.1 31.6 14.2 145.2 27.9 22.4 53.5 171.9 199.6 28.6 12.9 17.7 50.1 21.8 15.2 12.7 32.8 69.4 6.6 38.5 32.0 36.1 33.4 34.7 26.1 12.2 49.7 56.8 20.1 25.0 CDYL "CDYL1, DKFZP586C1622" ENSG00000153046 "Chromodomain Y like" Q9Y232 6 4706159-4955551 "Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Lyase, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 6.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035578 Enhanced Supported "Nuclear speckles" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 52: Non-specific - Ribosome" "Cluster 44: HDLM-2 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nuclear speckles" "HPA035578: AB_2674685" "unprognostic (1.25e-1)" "unprognostic (8.99e-2)" "unprognostic (6.03e-2)" "unprognostic (2.38e-3)" "prognostic favorable (1.53e-4)" "unprognostic (1.92e-1)" "prognostic unfavorable (2.20e-4)" "unprognostic (2.62e-2)" "prognostic unfavorable (7.52e-4)" "unprognostic (2.06e-1)" "unprognostic (2.05e-2)" "unprognostic (2.09e-1)" "unprognostic (5.21e-3)" "unprognostic (1.90e-1)" "unprognostic (1.65e-1)" "unprognostic (2.60e-2)" "unprognostic (3.94e-1)" 14.0 6.0 6.9 10.2 6.8 20.0 11.5 5.0 6.7 15.0 4.9 13.0 7.0 15.2 10.5 16.8 10.6 8.4 10.4 6.0 6.4 7.2 5.6 8.9 12.1 6.6 6.2 9.9 7.5 12.4 5.1 18.2 6.0 7.6 13.2 6.7 9.0 11.9 19.5 17.8 9.0 14.5 5.6 9.6 9.2 9.0 6.7 9.3 9.7 12.7 12.9 15.6 13.0 6.9 23.7 22.1 30.1 25.5 23.3 15.9 34.4 23.1 17.9 21.3 22.9 18.0 17.2 5.3 22.1 17.6 33.3 19.8 24.2 28.2 24.9 16.4 20.2 20.9 21.0 16.4 28.5 27.9 21.7 12.5 49.8 25.0 37.5 12.9 20.6 19.2 37.9 16.2 10.8 22.9 14.8 25.9 32.6 17.9 21.3 19.0 26.2 43.7 14.7 20.5 25.5 15.4 28.5 24.9 36.9 86.5 15.0 26.3 28.1 25.2 21.6 18.5 26.8 33.7 57.8 18.4 8.3 17.7 28.1 5.3 1.3 0.6 1.5 0.6 1.1 1.0 1.1 1.2 1.6 1.1 0.7 1.1 0.4 1.6 0.8 6.8 0.1 1.3 6.9 6.8 5.0 6.7 6.0 6.4 6.6 6.2 6.0 5.6 6.7 6.9 32.7 19.2 9.4 28.7 18.4 37.3 23.9 11.9 10.8 16.7 31.2 35.8 18.8 14.3 12.0 14.7 22.9 12.9 64.5 44.7 15.6 10.8 62.8 26.9 43.2 22.9 32.3 41.5 52.3 10.4 22.0 18.7 6.1 60.3 5.7 24.3 18.9 11.7 10.5 45.4 41.5 26.6 6.1 17.3 57.9 74.9 5.9 28.1 8.8 101.2 22.7 25.4 19.6 54.3 64.1 16.8 41.8 8.2 22.3 30.1 4.6 10.7 12.1 25.7 6.6 29.7 20.9 10.4 25.3 9.8 41.9 63.8 17.5 10.9 22.6 56.9 CHD5 ENSG00000116254 "Chromodomain helicase DNA binding protein 5" Q8TDI0 1 6101787-6180321 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Differentiation, Neurogenesis, Spermatogenesis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 59.0;pituitary gland: 57.3;testis: 31.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 84.3;Early spermatids: 217.8;Excitatory neurons: 80.4;Horizontal cells: 225.4;Inhibitory neurons: 56.2;Late spermatids: 113.2;Rod photoreceptor cells: 49.9" "Cancer enhanced" "Detected in single" "glioma: 0.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "SCLC-21H: 12.9;U-2 OS: 5.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015809 Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Nuclear speckles" Cytosol "HPA015809: " "unprognostic (5.03e-4)" "unprognostic (1.89e-1)" "unprognostic (2.47e-3)" "unprognostic (9.40e-6)" "unprognostic (1.91e-2)" "unprognostic (2.98e-2)" "unprognostic (1.06e-1)" "unprognostic (1.09e-1)" "unprognostic (2.97e-2)" "unprognostic (1.95e-2)" "unprognostic (6.64e-4)" "unprognostic (1.34e-1)" "unprognostic (1.34e-4)" "unprognostic (1.16e-1)" "unprognostic (1.63e-1)" "unprognostic (1.96e-1)" "unprognostic (1.98e-1)" 0.2 4.1 31.8 0.2 40.1 0.0 0.1 0.0 59.0 0.4 0.0 1.1 0.2 0.4 0.0 0.3 0.4 0.1 0.4 34.3 13.6 2.4 0.1 0.3 0.0 3.9 11.1 0.5 0.4 0.9 57.3 0.0 4.4 0.9 0.2 7.9 0.2 2.2 0.2 0.3 0.4 0.1 0.9 0.1 1.0 31.8 10.2 0.3 0.1 0.0 0.0 0.7 0.6 31.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.6 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 2.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.2 1.2 0.0 0.1 0.2 1.1 0.0 0.0 0.0 0.0 12.9 0.2 0.1 0.0 0.0 0.0 2.3 0.0 0.0 0.1 5.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.8 40.1 0.0 59.0 34.3 13.6 3.9 11.1 4.4 0.9 10.2 31.1 0.0 0.0 0.0 5.5 0.1 0.1 0.1 0.0 0.0 84.3 0.1 0.3 2.1 0.0 0.0 3.7 12.5 0.0 0.1 0.2 0.0 0.0 217.8 0.0 0.2 0.6 0.0 0.0 80.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 225.4 56.2 0.0 0.0 0.0 0.3 113.2 0.9 0.1 0.0 2.8 0.0 2.0 0.0 4.5 3.7 0.3 0.0 0.4 0.0 0.2 0.0 0.1 0.0 49.9 0.0 0.2 0.5 4.5 17.8 0.0 0.4 0.0 0.1 0.1 0.0 0.0 CIR1 CIR ENSG00000138433 "Corepressor interacting with RBPJ, CIR1" Q86X95 2 174348022-174395712 "Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 187.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 187.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015784, HPA061442" Approved Supported "Nuclear speckles" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" "HPA015784: AB_1846782, HPA061442: AB_2732664" "unprognostic (3.17e-3)" "unprognostic (4.07e-2)" "unprognostic (1.65e-1)" "prognostic unfavorable (9.56e-4)" "unprognostic (2.40e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (2.52e-4)" "unprognostic (1.00e-2)" "unprognostic (4.39e-2)" "prognostic favorable (9.80e-4)" "unprognostic (1.27e-1)" "unprognostic (3.66e-2)" "prognostic unfavorable (1.04e-7)" "unprognostic (2.23e-1)" "unprognostic (1.48e-1)" "unprognostic (8.10e-3)" "prognostic favorable (2.04e-5)" 26.7 23.8 36.3 23.4 38.1 67.3 35.9 38.5 61.1 26.6 39.5 27.7 25.8 27.4 43.5 20.3 28.3 23.4 28.7 36.0 37.3 25.9 27.5 26.7 31.1 36.8 37.0 33.7 24.9 27.4 25.1 29.8 36.6 26.2 26.3 23.6 24.9 26.0 30.7 30.5 26.7 20.7 35.9 35.0 25.5 31.4 36.3 32.3 29.0 25.2 29.5 24.0 24.2 40.1 20.4 11.4 26.5 21.2 36.3 50.4 39.2 32.9 46.5 32.3 39.5 21.5 30.7 14.1 30.3 32.4 28.3 24.0 22.1 23.4 38.6 26.1 29.1 29.4 17.8 34.9 35.1 35.2 26.0 41.7 41.9 35.5 26.5 55.6 32.4 24.9 30.7 30.8 31.0 19.5 44.1 55.6 24.5 33.2 31.6 24.7 38.1 42.2 38.4 32.1 30.7 36.1 22.7 28.7 52.9 45.7 21.6 51.6 33.6 26.1 19.0 24.9 17.3 34.6 31.4 5.2 37.4 18.2 23.3 71.0 33.8 55.9 28.4 31.7 28.4 41.2 32.2 30.5 21.4 40.5 33.4 30.9 187.8 45.3 33.9 39.5 37.2 28.3 36.3 38.1 38.5 61.1 36.0 37.3 36.8 37.0 36.6 35.9 36.3 40.1 82.0 118.6 79.8 30.0 80.8 28.6 52.2 118.6 39.3 51.7 40.6 66.8 61.4 61.5 101.2 42.3 31.3 72.7 116.5 69.1 119.3 67.3 201.5 192.2 79.7 58.7 51.4 102.5 30.4 78.7 58.1 69.9 30.1 79.6 81.6 59.1 75.7 58.6 63.8 45.4 33.7 81.9 85.5 93.0 30.3 43.4 107.2 75.3 33.8 22.5 108.2 85.7 111.2 30.2 37.3 57.7 79.8 82.4 49.1 37.5 91.6 114.0 202.3 56.2 72.3 71.4 72.1 219.5 54.7 25.4 32.0 116.0 80.5 62.6 53.5 45.7 COPS4 CSN4 ENSG00000138663 "COP9 signalosome subunit 4" Q9BT78 4 83034447-83075818 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036894, HPA042828" Approved Supported "Nuclear speckles" NA NA 100000 "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" "HPA036894: AB_10670929, HPA042828: AB_2678191" "unprognostic (1.82e-3)" "unprognostic (1.01e-2)" "prognostic favorable (4.14e-4)" "unprognostic (7.97e-3)" "unprognostic (1.39e-1)" "unprognostic (1.54e-1)" "unprognostic (1.73e-2)" "unprognostic (1.57e-1)" "unprognostic (8.96e-2)" "unprognostic (3.26e-1)" "unprognostic (3.10e-2)" "unprognostic (9.21e-2)" "prognostic favorable (5.21e-6)" "unprognostic (5.84e-2)" "unprognostic (3.07e-1)" "unprognostic (1.72e-1)" "unprognostic (2.80e-1)" 25.6 38.6 28.4 22.0 30.7 41.0 32.0 26.9 33.5 31.7 26.0 27.4 23.1 30.8 28.8 30.5 26.0 22.5 59.7 30.6 35.0 38.8 29.2 22.2 29.9 28.4 29.9 31.9 24.6 43.7 39.2 30.2 32.0 30.3 25.1 45.6 23.7 30.5 104.8 26.7 22.0 33.3 28.7 22.5 22.4 45.0 30.8 36.2 38.4 84.1 32.7 31.8 23.5 28.9 51.7 30.4 64.1 59.0 56.0 71.7 34.8 67.2 85.7 74.8 66.0 43.7 51.8 86.9 57.3 140.5 41.3 37.7 80.6 68.9 101.1 55.6 56.9 50.4 43.5 42.1 46.3 86.8 135.6 54.4 47.0 55.8 47.8 56.2 101.1 53.5 65.2 48.0 91.9 43.4 105.0 63.6 35.3 81.1 40.6 74.0 48.8 48.1 59.8 47.2 67.7 39.6 45.0 69.4 43.5 43.8 52.7 46.4 66.7 52.2 55.1 39.7 48.6 49.8 32.7 96.8 50.3 55.2 52.8 91.4 37.0 55.2 43.0 50.4 53.9 39.7 47.1 49.7 45.3 38.9 44.7 48.1 8.2 54.6 59.8 29.0 47.6 52.3 28.4 30.7 26.9 33.5 30.6 35.0 28.4 29.9 32.0 28.7 30.8 28.9 25.6 12.8 20.1 21.9 34.1 42.8 42.2 94.5 23.3 38.7 20.1 23.4 81.3 20.0 51.5 20.2 31.3 82.5 36.5 14.5 90.1 42.4 130.6 24.9 27.6 31.9 31.2 26.5 34.7 33.2 62.7 39.9 15.3 21.3 34.2 38.2 20.0 22.4 49.0 26.9 32.9 22.0 67.1 29.2 29.2 38.3 30.7 27.2 33.8 18.7 37.8 62.5 37.0 28.6 32.9 28.2 22.1 42.9 28.6 20.5 22.6 75.7 37.9 44.6 32.9 34.1 42.5 121.2 50.2 29.7 35.2 95.0 32.8 53.3 26.3 34.3 CRY2 ENSG00000121671 "Cryptochrome circadian regulator 2" Q49AN0 11 45847118-45883248 "Predicted intracellular proteins" "Biological rhythms, Sensory transduction, Transcription, Transcription regulation" "Photoreceptor protein, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Bipolar cells: 141.9;Horizontal cells: 101.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037577 Supported Supported "Nuclear speckles,Cytosol" "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "Nuclear speckles" Cytosol "HPA037577: AB_10672497" "unprognostic (1.67e-1)" "unprognostic (9.35e-2)" "prognostic unfavorable (1.67e-4)" "unprognostic (1.31e-2)" "unprognostic (9.16e-2)" "unprognostic (3.09e-2)" "prognostic favorable (6.82e-5)" "unprognostic (1.48e-3)" "unprognostic (1.67e-1)" "unprognostic (5.07e-2)" "prognostic favorable (4.39e-4)" "unprognostic (1.01e-1)" "prognostic favorable (6.44e-15)" "unprognostic (8.13e-3)" "unprognostic (1.89e-1)" "unprognostic (4.24e-2)" "unprognostic (2.24e-1)" 31.8 22.3 33.3 8.9 35.3 29.4 27.1 36.4 36.9 24.4 22.8 26.5 10.8 23.3 16.9 15.9 29.1 17.4 60.0 36.6 29.3 22.5 62.7 22.9 10.4 27.4 31.5 38.7 34.7 22.4 30.8 13.5 28.5 25.3 9.9 52.8 21.7 22.1 96.7 50.4 16.7 17.1 28.8 14.0 24.6 34.4 35.2 12.6 34.0 64.8 10.3 26.0 18.4 31.4 1.4 4.2 6.3 7.5 16.7 8.4 13.8 5.0 8.9 6.2 4.5 6.8 3.3 9.8 3.8 10.5 5.9 8.5 6.0 5.2 4.3 9.8 5.5 6.4 8.2 9.4 6.4 8.0 8.5 9.9 7.5 4.8 7.6 7.0 4.4 7.5 12.7 16.2 5.6 5.3 6.8 9.4 17.1 17.8 5.0 11.5 9.1 4.6 4.5 7.8 10.1 3.8 8.3 7.5 4.5 8.0 10.0 5.5 5.5 8.7 5.3 13.5 3.6 15.0 10.8 7.9 5.3 3.5 5.3 4.1 3.5 5.4 5.7 4.8 4.7 5.0 5.5 6.1 3.6 4.6 6.6 6.9 1.8 7.5 8.0 2.6 4.9 5.3 33.3 35.3 36.4 36.9 36.6 29.3 27.4 31.5 28.5 28.8 35.2 31.4 11.7 12.8 18.2 48.0 12.6 17.0 9.7 5.1 8.0 141.9 10.6 8.6 34.7 14.3 11.6 7.3 27.1 8.0 10.0 17.2 29.4 5.4 24.2 28.1 7.5 9.2 7.1 3.0 30.3 4.7 5.6 19.8 12.8 15.4 14.7 10.8 8.6 47.3 3.6 101.0 26.0 7.4 6.1 8.5 12.5 8.7 31.4 7.2 16.0 10.3 6.2 34.4 10.3 13.0 13.6 6.0 6.0 39.9 8.5 11.6 10.5 11.6 23.8 27.5 19.7 14.5 14.6 29.1 15.0 4.4 17.5 9.3 9.1 8.4 6.0 9.8 CWC22 "EIF4GL, fSAPb, KIAA1604, NCM" ENSG00000163510 "CWC22 spliceosome associated protein homolog" Q9HCG8 2 179944876-180007297 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036748 Approved Supported "Nuclear speckles,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 50: Fibroblasts - ECM organization" "Nuclear speckles" Cytosol "HPA036748: AB_10669913" "unprognostic (1.90e-1)" "unprognostic (7.10e-2)" "unprognostic (7.30e-2)" "unprognostic (6.14e-2)" "unprognostic (4.96e-2)" "unprognostic (4.33e-2)" "prognostic unfavorable (7.42e-4)" "unprognostic (3.15e-1)" "unprognostic (1.31e-2)" "unprognostic (3.30e-2)" "unprognostic (3.84e-2)" "unprognostic (4.80e-2)" "prognostic unfavorable (7.76e-5)" "unprognostic (1.74e-1)" "unprognostic (3.03e-2)" "unprognostic (1.41e-1)" "unprognostic (9.44e-3)" 12.7 10.2 7.1 13.1 7.8 16.0 15.0 13.5 10.1 14.1 7.1 11.9 10.1 16.9 10.4 12.5 12.0 12.1 10.1 7.6 7.2 13.4 16.8 11.5 18.5 6.4 6.9 19.3 9.2 13.5 8.2 14.5 7.0 12.5 11.8 12.4 10.2 10.9 13.6 11.0 10.4 13.9 7.1 14.7 11.0 9.0 7.0 21.8 16.0 14.5 18.2 14.1 12.1 8.9 19.1 11.2 31.6 21.1 22.7 26.7 24.1 24.5 28.7 29.4 28.7 25.9 23.1 36.7 21.6 17.9 25.6 20.5 30.4 23.1 44.2 33.0 26.2 49.1 15.1 35.4 22.0 69.6 26.2 17.5 27.1 37.4 49.8 19.3 22.3 25.2 54.6 21.9 19.7 18.9 36.5 34.7 48.8 22.5 18.3 32.8 38.9 27.7 20.2 23.5 21.6 28.8 20.3 15.9 28.5 33.8 11.8 42.2 19.0 25.1 21.2 16.8 25.7 19.2 21.5 44.3 22.6 27.2 26.1 49.7 13.3 31.4 16.1 16.7 16.3 17.4 17.3 19.5 13.9 14.5 21.1 16.7 22.0 16.0 13.3 8.6 16.5 11.5 7.1 7.8 13.5 10.1 7.6 7.2 6.4 6.9 7.0 7.1 7.0 8.9 38.0 19.2 33.8 20.5 38.0 19.1 29.2 16.9 22.2 19.5 12.9 19.8 26.6 22.8 27.0 11.0 25.0 18.3 36.5 11.8 9.8 23.4 1.6 24.2 31.9 27.2 15.6 14.9 35.8 19.1 17.5 32.5 19.9 25.1 27.3 24.7 16.8 12.8 13.7 13.5 28.4 16.4 14.2 20.6 12.1 2.4 23.3 24.2 3.6 15.0 31.6 17.3 30.9 35.2 35.1 18.7 17.6 18.4 20.8 16.8 15.7 20.3 34.4 19.1 46.0 40.3 25.1 22.8 21.3 14.1 18.6 24.8 32.5 18.6 15.6 19.5 CYGB "HGB, STAP" ENSG00000161544 Cytoglobin Q8WWM9 17 76527356-76551175 "Predicted intracellular proteins, Transporters" "Oxygen transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 104.4" "Cell type enhanced" "Detected in many" "Adipocytes: 94.3;Fibroblasts: 87.6;Leydig cells: 95.7;Melanocytes: 78.2;Sertoli cells: 92.1;Smooth muscle cells: 95.6" "Cancer enhanced" "Detected in all" "melanoma: 34.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 2.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 79.6;Hep G2: 61.7;HHSteC: 120.7;HSkMC: 95.4;SH-SY5Y: 129.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017757, HPA061642" Approved Approved Supported "Nuclear speckles,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Nuclear speckles" Cytosol "HPA017757: AB_1847410, HPA061642: AB_2684573" "unprognostic (6.96e-2)" "unprognostic (1.39e-1)" "unprognostic (3.97e-2)" "prognostic favorable (2.55e-5)" "prognostic unfavorable (1.85e-4)" "unprognostic (3.36e-2)" "unprognostic (3.31e-3)" "unprognostic (2.01e-1)" "unprognostic (7.83e-2)" "unprognostic (1.42e-1)" "unprognostic (1.08e-2)" "unprognostic (4.14e-2)" "prognostic unfavorable (2.13e-4)" "unprognostic (3.34e-2)" "unprognostic (1.11e-2)" "unprognostic (2.49e-2)" "unprognostic (7.76e-2)" 79.6 20.8 10.1 12.0 10.7 1.7 55.1 20.6 13.6 27.7 14.1 27.1 21.1 19.6 4.6 12.8 20.4 13.2 104.4 9.5 15.8 12.4 19.0 27.8 7.2 17.5 26.0 13.8 12.8 11.7 10.9 8.9 26.8 29.9 9.3 77.6 14.2 11.0 19.3 19.5 26.6 5.9 10.1 12.2 22.9 5.3 14.3 5.3 50.1 9.6 2.6 50.7 25.6 9.8 0.2 1.1 1.8 0.4 79.6 23.1 26.1 0.7 2.0 0.3 0.9 0.0 0.3 0.2 24.1 2.4 0.3 0.7 0.1 33.7 0.1 0.1 0.2 0.4 0.4 61.7 120.7 0.0 0.0 95.4 7.2 2.5 2.5 0.4 0.3 0.8 0.3 0.1 1.2 0.8 0.2 0.4 0.3 0.0 1.4 0.5 0.3 0.2 0.4 0.1 0.6 129.8 0.1 0.0 2.7 5.9 0.2 0.6 0.2 3.1 1.6 0.3 0.0 1.2 0.3 0.3 0.2 0.3 9.9 0.0 0.1 0.1 0.2 0.1 0.1 1.6 0.1 0.0 0.1 2.2 0.2 0.5 0.9 1.0 0.0 0.0 0.2 0.2 10.1 10.7 20.6 13.6 9.5 15.8 17.5 26.0 26.8 10.1 14.3 9.8 94.3 3.2 2.0 2.0 3.5 10.8 1.3 17.3 3.4 38.5 1.4 5.7 6.1 0.0 6.7 0.0 0.0 1.4 1.9 0.1 0.0 0.8 0.7 2.9 4.2 23.1 0.0 0.0 2.4 0.2 0.6 87.6 1.5 0.7 0.0 0.2 2.2 1.2 0.4 8.4 12.3 0.0 0.0 0.0 13.3 2.5 95.7 2.6 78.2 3.7 0.0 22.1 0.0 1.0 1.0 0.1 0.0 23.3 0.6 0.8 0.0 0.2 21.1 12.9 92.1 21.8 95.6 1.6 1.4 0.7 6.7 2.9 2.6 9.2 0.0 1.0 DACH1 DACH ENSG00000276644 "Dachshund family transcription factor 1" Q9UI36 13 71437966-71867204 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 88.5;Excitatory neurons: 77.0;Horizontal cells: 87.5;Late spermatids: 103.7;Microglial cells: 143.4;Muller glia cells: 143.8;Spermatocytes: 58.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "basophil: 4.2;eosinophil: 8.4;NK-cell: 4.2;plasmacytoid DC: 6.4" "Group enriched" "Detected in many" 33 "dendritic cells: 6.4;granulocytes: 8.4;NK-cells: 4.2" "Cell line enhanced" "Detected in some" "AF22: 14.2;HAP1: 22.5;HEK 293: 16.8;HL-60: 37.9;NB-4: 16.7;SCLC-21H: 36.9;SH-SY5Y: 29.5;THP-1: 26.9" "Region enriched" "Detected in all" 5 "basal ganglia: 38.8" "Region enriched" "Detected in all" 5 "basal ganglia: 34.2" "HPA012672, HPA012938, HPA073222" Approved Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Nuclear speckles" "HPA012672: AB_1847466, HPA012938: , HPA073222: " "unprognostic (3.16e-1)" "unprognostic (5.26e-2)" "unprognostic (1.41e-2)" "unprognostic (2.36e-1)" "unprognostic (4.21e-2)" "unprognostic (5.63e-2)" "unprognostic (2.22e-2)" "unprognostic (8.08e-3)" "unprognostic (2.12e-2)" "unprognostic (2.50e-1)" "unprognostic (3.04e-3)" "unprognostic (4.37e-1)" "unprognostic (2.18e-2)" "unprognostic (1.06e-1)" "unprognostic (2.19e-1)" "unprognostic (1.24e-1)" "unprognostic (5.17e-2)" 4.4 11.1 2.3 1.2 14.0 6.0 4.0 1.6 2.9 9.7 0.3 3.1 5.2 3.8 1.3 0.9 2.8 7.2 2.2 1.0 4.6 8.9 2.0 5.9 0.5 7.0 9.3 0.5 1.9 6.6 3.5 6.9 5.9 7.0 3.3 16.7 2.0 2.3 1.9 1.8 6.7 2.0 2.6 5.4 1.9 6.3 4.3 3.5 0.2 1.2 0.4 2.0 2.7 2.4 0.0 0.0 14.2 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 22.5 0.0 0.0 0.0 16.8 0.2 0.0 0.0 0.4 37.9 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.9 16.7 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 36.9 29.5 0.0 0.0 0.0 0.1 0.9 26.9 0.0 0.4 0.3 0.0 0.8 0.0 0.0 0.0 1.0 0.0 0.2 4.2 0.1 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 4.2 0.0 6.4 0.0 0.1 2.3 14.0 1.6 2.9 1.0 4.6 7.0 9.3 5.9 2.6 4.3 2.4 36.4 0.0 0.6 15.7 0.5 1.7 3.6 0.0 0.0 15.4 19.4 9.3 2.1 1.5 0.0 7.3 4.2 0.0 12.5 0.9 5.9 1.0 88.5 5.0 4.7 34.2 34.1 2.5 77.0 0.0 0.0 4.6 1.1 3.2 5.1 0.3 2.9 0.0 0.2 87.5 28.2 21.4 0.0 1.2 1.2 103.7 3.4 2.5 0.0 143.4 1.1 143.8 0.0 6.6 3.9 0.6 0.3 1.9 0.0 5.8 3.5 6.9 0.7 6.9 13.1 1.5 4.3 58.8 10.2 0.2 1.3 0.0 1.0 1.3 12.6 2.7 DAZAP2 KIAA0058 ENSG00000183283 "DAZ associated protein 2" Q15038 12 51238724-51271362 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045940 Supported "Nuclear speckles" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 3: HMC-1 - Innate immune response" "Cluster 59: Non-specific - Transcription" "Nuclear speckles" "HPA045940: AB_2679506" "unprognostic (1.00e-2)" "unprognostic (3.13e-2)" "unprognostic (7.35e-2)" "unprognostic (3.44e-2)" "unprognostic (1.00e-1)" "unprognostic (5.47e-2)" "unprognostic (4.75e-3)" "unprognostic (8.43e-2)" "unprognostic (4.75e-2)" "unprognostic (3.30e-1)" "unprognostic (5.80e-2)" "unprognostic (1.42e-1)" "prognostic favorable (3.94e-9)" "unprognostic (1.79e-1)" "unprognostic (2.40e-1)" "unprognostic (3.04e-1)" "unprognostic (5.84e-3)" 136.4 115.7 112.2 187.5 125.3 613.5 154.0 136.6 124.4 150.5 109.8 206.2 194.9 131.6 122.5 129.9 180.5 168.0 202.1 105.1 125.9 251.4 198.4 193.2 220.6 132.7 119.8 114.1 116.5 227.3 30.7 79.5 134.4 152.8 215.5 75.2 140.7 171.8 113.5 121.4 200.5 148.4 129.8 224.3 174.3 52.7 116.5 213.2 209.8 106.7 241.5 190.3 76.3 151.5 159.8 209.0 95.4 92.2 201.1 171.5 57.6 104.6 208.9 187.7 162.8 155.9 239.0 153.2 262.2 209.9 130.0 147.8 134.2 178.4 189.2 167.3 160.2 227.1 129.7 91.0 216.4 265.5 350.2 220.5 252.1 175.3 147.2 207.2 234.8 118.8 141.6 303.1 155.4 252.6 219.8 145.6 19.6 109.2 58.7 123.2 144.7 165.3 244.9 260.2 103.3 101.0 159.3 137.9 121.3 56.7 190.5 382.7 195.7 111.1 102.4 136.9 132.6 231.5 237.5 158.6 161.2 175.0 66.9 2018.1 2144.1 3354.3 1055.9 1770.0 979.3 1090.7 962.8 1037.9 1354.1 1068.7 1063.1 918.3 3499.5 1045.4 1727.1 875.9 1420.3 4885.3 112.2 125.3 136.6 124.4 105.1 125.9 132.7 119.8 134.4 129.8 116.5 151.5 116.7 144.2 205.1 19.6 271.9 113.8 201.2 144.6 167.9 50.6 127.7 88.5 114.3 165.8 127.9 235.4 58.4 55.8 167.4 337.2 266.1 158.6 28.1 115.1 87.2 138.3 126.3 155.6 16.8 194.7 53.5 108.0 171.8 142.1 182.2 72.2 157.1 177.1 209.4 67.3 16.8 230.6 140.4 444.4 214.2 85.6 117.4 282.0 135.2 19.7 324.4 88.7 221.4 15.6 43.9 198.0 275.8 95.5 169.5 179.9 233.3 292.7 155.9 55.2 46.0 63.2 130.4 39.4 35.4 153.5 133.3 124.9 249.6 72.8 182.4 268.7 DDX17 P72 ENSG00000100201 "DEAD-box helicase 17" Q92841 22 38483438-38507660 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Immunity, mRNA processing, mRNA splicing, RNA-mediated gene silencing, rRNA processing, Transcription, Transcription regulation" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB024908, HPA063142" Supported Supported "Nuclear speckles" "Intracellular and membrane" NA NA 420000 "Cluster 1: Neutrophils - Mixed function" "Cluster 51: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "CAB024908: , HPA063142: AB_2684949" "unprognostic (1.46e-2)" "unprognostic (5.99e-3)" "unprognostic (4.24e-3)" "unprognostic (6.67e-2)" "unprognostic (1.06e-2)" "unprognostic (1.02e-2)" "unprognostic (1.36e-2)" "prognostic favorable (6.06e-4)" "unprognostic (1.17e-1)" "unprognostic (5.51e-1)" "unprognostic (2.52e-2)" "unprognostic (2.73e-2)" "unprognostic (1.89e-2)" "unprognostic (2.19e-2)" "unprognostic (1.76e-1)" "unprognostic (4.31e-2)" "unprognostic (3.19e-3)" 181.2 172.4 142.0 124.3 160.1 74.5 198.5 150.9 178.4 248.7 174.8 233.8 107.8 216.1 255.3 150.4 248.1 121.1 168.7 143.5 152.1 247.2 152.8 202.2 186.4 152.8 149.4 298.8 214.0 144.7 309.9 158.8 155.3 234.4 114.2 342.0 188.4 123.3 184.8 197.0 227.2 119.7 146.8 293.0 192.1 91.1 148.2 215.2 300.0 106.6 158.2 204.4 201.5 196.5 122.0 79.9 237.6 141.8 148.2 166.0 120.7 104.3 85.9 118.3 121.2 89.0 100.5 225.8 65.8 119.5 82.9 133.2 212.5 127.9 145.9 202.5 142.1 140.4 175.8 133.5 153.4 192.9 170.8 122.3 183.7 86.8 142.9 211.7 153.3 109.6 139.7 255.3 116.0 75.6 128.7 164.0 148.0 172.1 51.6 218.0 122.9 137.1 141.2 132.6 134.1 75.3 155.0 125.9 161.2 180.5 110.0 148.4 140.8 125.7 77.6 80.0 79.3 203.7 130.3 183.4 156.7 123.1 154.2 6.7 8.1 9.5 7.6 7.9 8.9 9.0 7.1 7.3 7.0 7.2 5.7 6.8 16.6 5.1 8.7 10.5 9.1 6.0 142.0 160.1 150.9 178.4 143.5 152.1 152.8 149.4 155.3 146.8 148.2 196.5 252.6 214.7 325.5 483.8 241.9 223.6 206.1 129.3 158.2 448.3 300.7 195.3 147.2 180.1 223.5 283.3 352.3 127.6 297.5 172.8 33.2 111.7 44.4 280.0 293.4 250.4 236.1 177.1 198.9 90.2 99.9 207.5 216.1 234.2 200.7 505.3 233.8 205.3 113.9 321.4 242.1 191.6 146.5 200.6 194.8 49.1 323.7 197.7 154.7 253.9 235.1 223.4 304.9 334.3 553.3 104.7 153.1 278.7 213.1 193.5 154.8 89.8 270.8 559.4 289.3 260.5 213.6 136.4 74.2 120.4 279.9 139.4 218.6 293.7 147.0 255.3 DDX46 "FLJ25329, KIAA0801, Prp5, PRPF5" ENSG00000145833 "DEAD-box helicase 46" Q7L014 5 134758771-134855133 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036554, HPA057501" Supported Supported "Nucleoli fibrillar center,Nuclear speckles" NA NA 13000 "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "Nucleoli fibrillar center" "HPA036554: AB_10673621, HPA057501: AB_2683449" "unprognostic (1.88e-1)" "unprognostic (1.21e-1)" "prognostic favorable (9.01e-6)" "unprognostic (7.00e-2)" "unprognostic (3.37e-2)" "unprognostic (1.71e-2)" "unprognostic (2.04e-3)" "unprognostic (1.07e-1)" "unprognostic (1.60e-2)" "unprognostic (5.05e-2)" "unprognostic (9.21e-2)" "unprognostic (6.02e-2)" "unprognostic (9.70e-3)" "unprognostic (4.36e-2)" "unprognostic (4.35e-2)" "unprognostic (1.64e-2)" "unprognostic (4.50e-2)" 16.5 14.6 7.6 23.9 8.8 23.1 17.7 16.1 10.8 16.3 11.4 17.3 17.0 19.8 12.3 17.5 15.0 13.4 13.4 6.8 11.2 18.8 17.7 15.8 25.6 10.0 8.4 18.5 20.8 18.4 11.1 15.7 9.2 15.5 20.7 18.0 16.8 12.1 35.2 19.4 18.7 17.6 5.4 20.6 20.0 16.3 10.0 32.1 18.7 22.9 26.6 18.2 15.6 10.3 87.1 78.0 54.4 71.1 20.8 23.2 75.0 56.8 43.7 58.8 65.6 119.2 61.7 108.9 47.7 38.3 62.3 52.5 80.9 54.2 68.7 73.8 73.3 131.0 84.7 48.5 18.0 120.5 67.8 21.0 28.9 62.1 34.8 24.9 47.3 85.9 113.6 45.3 44.1 41.5 104.2 46.9 75.2 50.1 34.8 89.7 142.0 54.8 32.0 73.9 64.2 61.3 79.4 37.2 42.7 63.0 58.3 68.0 59.0 61.8 43.2 47.9 114.0 35.6 103.2 140.2 42.8 112.0 40.0 55.6 31.9 48.2 30.7 29.2 28.0 38.1 30.4 31.3 25.3 43.4 30.9 31.5 55.9 32.3 27.5 38.5 29.7 17.8 7.6 8.8 16.1 10.8 6.8 11.2 10.0 8.4 9.2 5.4 10.0 10.3 102.4 76.9 131.5 35.9 123.6 113.8 121.5 102.7 68.9 131.5 80.6 79.4 69.3 64.3 94.9 103.0 83.4 133.7 142.3 91.3 56.7 100.5 53.4 111.4 155.8 104.7 92.2 90.6 38.7 107.9 160.4 85.1 69.3 115.9 101.2 122.3 76.8 113.1 94.4 121.1 41.2 112.4 63.1 119.3 113.2 26.7 111.9 103.4 56.9 21.5 178.5 79.9 194.7 28.1 57.6 130.7 62.6 113.2 134.7 139.5 79.2 84.1 74.5 176.0 98.6 114.9 115.2 246.3 275.7 81.0 137.0 157.2 131.8 114.5 112.7 144.1 DGKZ "DAGK5, DAGK6, DGK-ZETA, hDGKzeta" ENSG00000149091 "Diacylglycerol kinase zeta" Q13574 11 46332905-46380554 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 146.2" "Cell type enhanced" "Detected in all" "NK-cells: 129.8" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 27 "amygdala: 46.5;basal ganglia: 75.1;cerebral cortex: 146.2;hippocampal formation: 133.8;white matter: 51.0" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051336 Enhanced Supported Supported "Nuclear speckles" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear speckles" "HPA051336: AB_2681448" "unprognostic (2.85e-2)" "unprognostic (3.90e-2)" "unprognostic (2.39e-1)" "unprognostic (1.65e-1)" "unprognostic (1.40e-1)" "unprognostic (4.12e-2)" "unprognostic (3.08e-3)" "unprognostic (1.31e-1)" "unprognostic (1.03e-2)" "unprognostic (2.49e-2)" "unprognostic (3.66e-3)" "unprognostic (8.18e-2)" "prognostic unfavorable (4.74e-5)" "unprognostic (1.48e-3)" "unprognostic (7.75e-2)" "unprognostic (3.61e-2)" "unprognostic (7.84e-3)" 20.7 14.2 46.5 21.6 75.1 54.6 19.4 3.3 146.2 16.5 0.0 20.3 36.4 16.8 4.0 19.5 15.3 11.1 46.5 133.8 0.0 18.3 10.5 18.3 39.9 0.0 0.0 12.4 31.5 10.0 58.7 14.1 0.0 18.6 6.6 2.5 43.4 10.7 95.7 22.3 41.2 9.1 0.0 36.1 22.2 15.4 1.4 34.0 12.5 25.1 17.1 18.2 15.3 51.0 38.1 33.2 22.1 33.2 11.5 12.8 102.1 29.0 21.5 30.0 26.3 39.8 17.1 48.4 20.5 30.1 33.0 43.3 26.7 42.0 10.6 48.8 62.5 31.7 25.2 29.5 20.5 60.5 61.2 17.3 19.3 16.5 22.2 15.3 33.4 39.3 45.1 29.1 21.5 99.8 58.6 94.3 64.3 54.5 50.3 69.0 38.2 20.6 9.1 36.6 150.3 25.6 33.2 109.6 23.0 13.8 78.8 75.2 37.9 39.2 42.4 62.6 52.9 19.1 23.4 40.3 53.8 54.0 37.2 12.4 13.5 6.0 6.8 5.6 4.1 0.3 4.3 5.9 12.0 0.8 4.3 4.6 9.5 7.6 6.4 5.7 4.4 10.5 46.5 75.1 3.3 146.2 133.8 0.0 0.0 0.0 0.0 0.0 1.4 51.0 46.0 3.2 6.6 44.7 16.4 13.3 22.3 16.3 14.2 27.6 24.6 19.8 24.4 8.6 8.7 9.2 20.9 14.6 95.8 37.7 9.8 13.2 6.1 9.9 15.2 34.2 51.5 23.4 114.0 47.8 105.1 12.4 34.1 14.1 21.0 25.7 56.7 7.1 51.2 16.8 45.0 26.3 22.4 46.1 26.9 11.4 13.1 34.0 12.4 31.9 50.6 6.4 129.8 8.5 24.7 33.5 41.0 8.2 25.3 16.6 97.0 20.2 8.2 9.9 32.9 17.8 16.8 7.0 12.2 12.3 9.2 27.4 71.8 19.4 29.9 17.2 E2F3 ENSG00000112242 "E2F transcription factor 3" O00716 6 20401879-20493714 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 67.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029779, HPA065012" Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Nuclear speckles" Cytosol "HPA029779: AB_2732448, HPA065012: AB_2685403" "unprognostic (4.10e-2)" "unprognostic (1.15e-1)" "unprognostic (1.06e-1)" "unprognostic (1.80e-3)" "unprognostic (2.96e-1)" "unprognostic (9.14e-2)" "unprognostic (8.99e-3)" "unprognostic (9.13e-2)" "unprognostic (1.10e-1)" "prognostic favorable (1.69e-4)" "unprognostic (1.14e-2)" "unprognostic (5.64e-2)" "prognostic unfavorable (1.63e-8)" "unprognostic (1.23e-1)" "unprognostic (2.16e-1)" "unprognostic (3.50e-1)" "unprognostic (5.99e-3)" 6.5 4.9 4.8 9.8 5.2 19.8 4.1 2.8 5.7 3.3 3.0 5.4 5.2 3.6 3.9 4.9 2.5 6.4 5.1 6.4 4.6 5.8 4.4 4.9 11.0 3.7 4.6 1.4 2.1 3.1 1.8 5.6 4.2 3.3 6.3 6.1 2.7 3.1 10.0 2.6 5.7 6.0 3.7 8.4 3.6 3.4 5.5 8.6 8.5 9.3 9.5 8.5 2.7 3.8 14.3 11.6 32.2 35.1 10.9 11.9 22.0 18.9 16.8 18.2 19.9 14.3 8.8 32.3 35.2 18.2 16.9 14.6 37.8 17.4 30.3 12.2 25.3 58.1 20.4 16.3 11.6 38.6 33.0 9.7 12.6 17.7 21.6 18.8 12.7 29.8 65.3 19.4 20.9 15.0 43.6 43.2 24.2 11.0 11.9 46.5 27.8 36.5 21.8 25.1 22.9 42.2 17.3 24.1 26.3 20.0 12.4 23.4 17.2 28.6 17.4 14.2 30.5 12.1 40.1 38.3 7.1 23.2 41.3 5.6 2.3 1.1 1.6 1.6 2.0 0.4 1.0 2.4 2.6 0.4 0.8 1.8 7.2 3.5 1.1 1.1 1.6 1.1 4.8 5.2 2.8 5.7 6.4 4.6 3.7 4.6 4.2 3.7 5.5 3.8 4.8 0.0 2.6 53.8 10.6 9.2 12.3 7.0 7.4 34.1 11.9 7.2 10.6 4.3 10.6 7.3 22.9 8.3 15.0 12.0 9.8 7.6 12.2 3.9 14.1 8.5 12.0 17.2 67.7 6.9 13.8 9.2 12.8 10.6 20.3 32.3 14.6 4.7 17.1 32.0 31.9 11.7 4.1 47.2 17.7 5.7 2.8 28.7 5.4 27.2 23.8 2.9 15.5 37.7 2.9 14.8 10.3 3.0 19.1 22.1 4.5 25.1 2.2 9.0 0.0 9.0 11.5 3.0 4.7 16.5 8.9 3.1 15.3 5.7 13.8 18.4 E2F7 ENSG00000165891 "E2F transcription factor 7" Q96AV8 12 77021248-77065569 "Predicted intracellular proteins, Transcription factors" "Cell cycle, DNA damage, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.0;lymphoid tissue: 8.3" "Cell type enhanced" "Detected in many" "Early spermatids: 46.9;Endometrial ciliated cells: 17.2;Late spermatids: 70.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.7" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "midbrain: 5.8;pons: 6.4;thalamus: 11.3" HPA064866 Supported "Nuclear speckles" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" "Nuclear speckles" "HPA064866: AB_2685374" "unprognostic (1.21e-1)" "unprognostic (8.92e-2)" "unprognostic (7.39e-2)" "unprognostic (7.27e-2)" "unprognostic (1.54e-1)" "unprognostic (3.80e-2)" "unprognostic (6.14e-5)" "unprognostic (1.05e-3)" "unprognostic (1.72e-1)" "unprognostic (3.57e-2)" "unprognostic (5.67e-5)" "unprognostic (1.42e-1)" "unprognostic (0.00e+0)" "unprognostic (3.05e-2)" "unprognostic (1.57e-1)" "unprognostic (1.00e-1)" "unprognostic (2.51e-1)" 0.2 0.1 0.2 1.1 0.2 5.0 0.2 0.0 0.3 0.3 0.3 0.9 0.7 0.2 0.0 1.4 0.6 0.7 0.2 0.2 0.2 0.1 0.2 0.3 1.5 0.7 0.8 0.1 0.2 0.1 0.5 1.0 0.4 0.2 1.5 0.2 0.2 0.1 0.0 1.1 0.8 0.3 0.6 0.3 0.6 2.9 0.2 8.3 0.1 0.1 1.6 0.6 0.5 0.2 20.1 9.4 25.7 10.1 0.8 2.5 31.1 27.6 29.8 14.2 17.0 12.8 6.6 11.2 5.4 5.5 29.5 15.1 15.5 29.8 27.1 4.4 10.4 9.8 27.3 7.3 5.9 8.5 8.8 0.8 7.7 37.4 22.9 8.3 14.2 19.0 10.4 8.9 29.5 10.1 31.9 0.1 18.1 6.7 21.9 23.0 22.2 6.2 3.5 16.8 16.3 10.7 22.9 7.9 6.5 10.9 12.6 8.7 39.3 53.5 26.8 23.0 36.7 9.5 5.8 7.1 19.3 3.8 34.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.7 0.4 0.0 0.2 0.2 0.0 0.3 0.2 0.2 0.7 0.8 0.4 0.6 0.2 0.2 0.1 0.0 0.5 2.3 0.5 0.3 1.0 1.4 4.6 0.0 0.6 0.9 2.1 0.0 2.2 0.0 0.0 1.8 0.4 1.5 0.0 0.3 46.9 17.2 0.8 1.5 0.0 7.4 0.4 1.1 3.1 0.8 6.1 3.1 4.5 6.3 0.0 0.0 0.9 0.0 0.2 1.2 2.0 0.3 1.2 70.2 0.3 1.3 0.0 3.7 0.0 1.6 0.0 0.5 0.0 12.0 0.1 0.7 6.9 1.7 0.0 0.0 3.1 0.1 0.0 0.0 1.2 1.2 2.1 6.3 0.6 0.3 0.8 0.4 2.1 4.3 EHMT2 "BAT8, C6orf30, Em:AF134726.3, G9A, KMT1C, NG36/G9a" ENSG00000204371 "Euchromatic histone lysine methyltransferase 2" Q96KQ7 6 31879759-31897687 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Chromatin regulator, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HL-60: 13.3;NTERA-2: 19.3;U-266/84: 16.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050550, HPA060259" Supported Supported "Nucleoplasm,Nuclear speckles" "Intracellular and membrane" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 5: NTERA-2 - Transcription" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" Nucleoplasm "HPA050550: AB_2681170, HPA060259: AB_2684234" "unprognostic (3.11e-2)" "unprognostic (2.72e-1)" "unprognostic (4.39e-2)" "unprognostic (1.92e-2)" "unprognostic (5.44e-2)" "unprognostic (3.51e-2)" "prognostic unfavorable (1.79e-4)" "unprognostic (3.55e-2)" "unprognostic (7.41e-2)" "unprognostic (1.01e-1)" "unprognostic (5.89e-2)" "unprognostic (1.88e-1)" "unprognostic (9.78e-3)" "unprognostic (8.72e-2)" "unprognostic (1.84e-1)" "unprognostic (2.25e-1)" "unprognostic (9.03e-2)" 8.6 9.6 0.5 0.3 0.4 1.0 8.7 0.4 0.5 15.1 0.2 12.9 2.4 19.8 1.7 10.1 12.8 0.0 5.7 0.4 0.4 7.1 4.6 7.3 1.0 0.4 0.5 16.1 7.8 0.6 12.8 0.7 0.4 10.3 0.3 0.6 9.5 1.3 5.5 9.3 10.5 1.4 0.4 11.5 9.4 12.6 0.5 1.5 10.3 0.4 1.0 13.1 11.3 0.4 0.0 4.5 7.8 0.0 3.4 1.8 5.0 3.5 2.8 3.9 3.2 0.0 0.0 0.0 7.6 5.7 4.0 0.0 0.0 8.6 1.8 5.4 11.8 0.0 0.0 0.1 0.0 13.3 0.0 4.6 1.4 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 9.4 0.0 19.3 0.0 0.0 8.8 0.0 0.0 1.5 0.0 0.0 0.0 0.0 2.3 6.5 3.1 0.0 0.0 3.8 4.1 3.1 6.9 0.0 11.0 16.1 3.8 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.5 0.4 0.4 0.5 0.4 0.4 0.4 0.5 0.4 0.4 0.5 0.4 16.9 16.0 12.0 22.9 20.3 8.4 6.3 11.9 26.2 60.6 15.9 17.8 6.6 17.2 18.9 25.8 41.7 24.6 13.4 9.2 7.9 15.7 41.5 10.1 19.1 16.1 22.6 19.3 16.6 12.2 15.0 16.0 13.3 11.8 14.5 33.8 22.1 7.5 16.3 38.7 24.4 16.4 12.2 12.9 7.3 60.0 27.4 12.1 19.6 9.4 19.9 26.8 25.7 20.1 23.9 10.8 9.1 23.0 16.5 6.2 12.5 10.1 10.8 48.2 26.3 16.3 15.0 20.8 33.7 23.5 11.1 5.6 18.3 19.9 19.0 5.2 ELOA "SIII, TCEB3, TCEB3A" ENSG00000011007 "Elongin A" Q14241 1 23743155-23762059 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 83.9;Ductal cells: 41.3;Syncytiotrophoblasts: 41.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005910 Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 18: U-2197 - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Nuclear speckles" Cytosol "HPA005910: AB_1080227" "unprognostic (6.90e-2)" "unprognostic (5.99e-3)" "unprognostic (4.08e-2)" "unprognostic (1.44e-1)" "unprognostic (1.99e-1)" "unprognostic (3.93e-2)" "prognostic unfavorable (1.44e-5)" "unprognostic (1.72e-1)" "unprognostic (8.84e-3)" "unprognostic (6.00e-2)" "unprognostic (4.94e-2)" "unprognostic (2.14e-2)" "unprognostic (2.95e-3)" "unprognostic (2.90e-1)" "unprognostic (4.27e-2)" "unprognostic (4.80e-2)" "unprognostic (4.14e-2)" 25.7 12.7 9.8 18.8 10.8 33.4 16.5 13.0 11.5 15.7 10.4 14.8 12.6 13.3 10.1 23.8 12.9 15.4 15.5 10.1 10.9 14.4 29.6 25.8 17.7 10.9 10.6 16.1 42.4 27.0 11.5 19.2 11.0 14.9 16.5 12.7 17.4 13.3 33.2 20.1 13.9 16.8 9.7 16.2 26.5 18.9 11.1 21.6 21.3 26.4 23.6 24.5 14.6 11.8 52.0 28.3 40.2 34.6 46.2 28.6 25.3 52.4 46.9 76.2 66.1 34.9 44.1 27.0 62.7 53.3 42.8 48.5 83.0 55.2 84.4 77.8 41.1 60.9 42.2 41.1 40.9 64.7 35.3 30.6 43.6 83.3 63.2 28.2 46.4 43.7 91.8 45.3 61.6 39.3 33.5 26.1 46.8 57.7 42.4 49.8 50.9 51.3 35.8 34.8 76.2 42.9 47.7 47.5 58.5 44.3 34.4 23.5 49.5 59.5 52.8 106.9 62.5 46.8 56.4 59.2 52.1 63.2 60.7 28.2 24.6 19.6 16.5 24.9 16.3 23.5 13.8 15.1 22.6 18.5 11.2 14.9 6.5 13.7 24.1 18.4 17.1 17.7 9.8 10.8 13.0 11.5 10.1 10.9 10.9 10.6 11.0 9.7 11.1 11.8 24.1 28.9 83.9 0.0 7.9 0.0 0.0 0.0 0.0 0.0 19.6 16.0 0.0 0.0 18.0 18.4 0.0 28.1 17.5 0.0 5.9 41.3 0.0 15.4 27.4 12.5 0.0 0.0 0.0 32.7 35.7 10.1 0.0 23.3 13.9 21.5 0.0 0.0 28.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 35.2 0.0 0.0 0.0 0.0 37.9 0.0 0.0 4.9 0.0 0.0 19.0 16.8 0.0 0.0 0.0 12.8 0.0 0.0 0.0 0.0 41.3 9.6 32.5 0.0 0.0 ERBIN "ERBB2IP, LAP2" ENSG00000112851 "Erbb2 interacting protein" Q96RT1 5 65926556-66082546 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 119.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 70.5;dendritic cells: 61.3;Endometrial ciliated cells: 62.3;Glandular and luminal cells: 101.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048606, HPA059863" Approved Supported "Nuclear speckles,Plasma membrane" NA NA 39000 "Cluster 38: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 7: Non-specific - Mitochondria" "Nuclear speckles, Plasma membrane" "HPA048606: AB_2680461, HPA059863: AB_2684146" "unprognostic (4.34e-1)" "unprognostic (5.56e-2)" "unprognostic (9.88e-2)" "unprognostic (2.15e-2)" "unprognostic (2.04e-1)" "unprognostic (4.23e-3)" "unprognostic (1.74e-1)" "unprognostic (1.01e-1)" "unprognostic (1.46e-2)" "unprognostic (6.52e-2)" "unprognostic (5.45e-3)" "unprognostic (7.98e-2)" "unprognostic (5.62e-3)" "unprognostic (7.21e-3)" "unprognostic (3.08e-1)" "unprognostic (6.86e-2)" "unprognostic (7.81e-2)" 15.7 14.5 65.2 29.5 109.6 30.0 24.7 64.2 67.6 23.2 19.0 27.8 24.5 22.6 27.0 20.1 20.0 28.4 16.9 56.2 91.6 29.5 33.3 21.5 40.6 91.3 88.0 20.0 18.8 22.6 8.3 16.4 106.0 26.4 26.3 28.1 21.8 20.2 19.8 32.8 44.1 19.7 64.4 31.4 40.3 27.5 86.6 48.7 29.9 20.7 39.0 28.5 13.0 119.1 97.8 32.2 41.5 49.6 30.0 36.0 31.5 61.5 62.6 85.3 94.3 31.5 113.8 82.2 58.8 95.3 67.2 31.7 26.5 45.1 149.4 36.3 12.0 28.3 41.3 24.7 39.5 22.0 26.3 39.4 29.2 47.2 67.5 50.0 32.1 37.1 29.4 54.6 58.1 33.5 59.0 25.1 10.1 9.7 9.5 53.7 33.0 45.8 49.9 65.6 20.0 18.7 65.0 21.7 46.4 30.9 38.4 53.8 29.8 48.3 85.9 29.8 80.8 47.2 31.7 69.8 31.6 35.9 28.1 13.1 4.1 5.5 5.2 5.8 4.8 4.7 3.9 4.6 3.5 3.7 4.5 4.8 9.2 3.9 5.1 2.2 3.8 2.8 65.2 109.6 64.2 67.6 56.2 91.6 91.3 88.0 106.0 64.4 86.6 119.1 53.0 70.5 57.5 0.0 13.2 0.0 0.0 0.0 0.0 0.0 39.4 24.8 0.0 0.0 31.6 53.3 0.0 6.5 61.3 0.0 11.7 26.7 0.0 62.3 50.0 26.1 0.0 0.0 0.0 24.9 11.2 16.2 0.0 101.9 27.8 47.8 0.0 0.0 40.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.4 0.0 0.0 5.7 0.0 0.0 0.0 0.0 50.3 0.0 0.0 13.3 0.0 0.0 41.7 24.0 0.0 0.0 0.0 17.1 0.0 0.0 0.0 0.0 8.9 20.0 51.4 0.0 0.0 ESX1 "ESX1L, ESXR1" ENSG00000123576 "ESX homeobox 1" Q8N693 X 104250038-104254933 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 69 "testis: 8.9" "Cell type enriched" "Detected in some" 25 "Spermatogonia: 98.0" "Cancer enriched" "Detected in single" 5 "testis cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "TIME: 24.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA051992, HPA073330" Enhanced Supported "Nuclear speckles" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nuclear speckles" "HPA051992: AB_2681684, HPA073330: " "unprognostic (1.87e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 24.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 98.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 EXOSC7 "EAP1, hRrp42p, KIAA0116, p8, RRP42, Rrp42p" ENSG00000075914 "Exosome component 7" Q15024 3 44975241-45036066 "Predicted intracellular proteins" "rRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036182, HPA057980" Approved Supported "Nuclear speckles" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 24: NB-4 - Immune response" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "HPA036182: AB_10673346, HPA057980: AB_2683571" "unprognostic (1.69e-2)" "unprognostic (3.92e-3)" "unprognostic (1.84e-3)" "unprognostic (4.97e-2)" "unprognostic (3.00e-3)" "unprognostic (2.16e-1)" "unprognostic (2.34e-3)" "unprognostic (2.21e-2)" "unprognostic (2.96e-1)" "unprognostic (7.85e-2)" "unprognostic (1.20e-1)" "unprognostic (7.67e-3)" "prognostic favorable (2.69e-4)" "unprognostic (4.33e-1)" "unprognostic (7.30e-2)" "unprognostic (2.94e-1)" "unprognostic (1.20e-1)" 17.5 44.1 9.5 12.5 9.5 17.2 18.4 10.0 10.4 23.5 10.7 15.3 11.6 20.4 7.0 27.2 17.0 9.1 27.0 9.5 10.9 22.2 18.1 15.0 19.6 10.4 9.8 19.0 18.6 20.1 17.3 15.4 10.1 15.9 10.8 5.9 17.5 15.9 43.8 44.6 13.2 11.2 9.7 15.3 20.0 23.2 10.5 20.2 19.9 36.4 16.8 22.7 22.2 9.8 61.5 55.7 44.9 37.3 45.9 50.0 40.5 26.2 42.2 56.0 57.7 93.3 47.8 77.4 40.3 45.6 42.6 33.9 55.9 72.2 46.0 52.3 49.2 67.5 64.5 91.5 88.7 95.3 26.5 44.1 45.6 61.2 123.6 36.5 54.8 84.9 107.4 37.8 40.3 63.2 68.6 167.9 54.3 55.2 78.4 33.8 41.7 117.7 51.0 85.5 20.9 31.4 37.0 31.6 39.7 38.4 46.7 77.9 39.3 28.8 43.0 48.3 71.7 47.1 47.5 92.6 42.4 131.6 26.2 6.8 41.3 7.6 38.8 41.5 43.6 71.3 44.6 40.2 66.0 59.7 51.8 41.4 2.1 58.3 31.5 40.2 47.7 45.4 9.5 9.5 10.0 10.4 9.5 10.9 10.4 9.8 10.1 9.7 10.5 9.8 25.0 35.3 30.1 16.0 23.2 61.8 68.8 97.2 47.3 29.5 23.9 43.2 39.0 21.5 46.5 35.0 18.8 67.8 22.1 8.6 135.0 51.7 3.9 23.7 34.8 24.0 13.1 19.6 19.9 46.7 62.4 32.7 23.0 21.7 15.2 33.0 18.2 28.6 46.5 20.2 22.5 19.3 79.3 14.2 22.6 8.3 47.8 17.4 26.6 8.4 20.6 37.6 33.0 10.6 14.0 41.7 10.3 41.0 19.4 74.8 17.7 47.4 34.3 23.4 13.1 25.7 53.9 53.7 66.3 35.5 74.2 63.1 26.2 52.2 24.3 56.3 FAM107A "DRR1, TU3A" ENSG00000168309 "Family with sequence similarity 107 member A" O95990 3 58564117-58627610 "Predicted intracellular proteins" "Cell cycle, Growth regulation, Stress response" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "brain: 1923.8;choroid plexus: 1389.1" "Cell type enhanced" "Detected in many" "Adipocytes: 196.3;Astrocytes: 81.9;Endothelial cells: 121.3;Hepatic stellate cells: 150.6;Muller glia cells: 125.0" "Cancer enriched" "Detected in many" 6 "glioma: 110.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "ASC diff: 20.7;HUVEC TERT2: 64.9" "Low region specificity" "Detected in all" HPA055888 Enhanced Supported "Nuclear speckles" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles" "HPA055888: AB_2682957" "unprognostic (1.20e-2)" "unprognostic (1.19e-3)" "unprognostic (1.47e-2)" "prognostic unfavorable (3.56e-4)" "unprognostic (3.11e-1)" "unprognostic (7.80e-3)" "prognostic favorable (3.38e-4)" "unprognostic (1.92e-1)" "unprognostic (1.64e-1)" "unprognostic (5.73e-2)" "unprognostic (7.82e-3)" "unprognostic (2.22e-2)" "unprognostic (1.33e-2)" "unprognostic (1.33e-2)" "unprognostic (2.82e-1)" "unprognostic (1.92e-1)" "unprognostic (7.95e-3)" 73.2 7.5 1824.7 8.3 1801.2 0.3 58.6 1490.8 1923.8 34.5 1389.1 36.9 5.4 36.3 53.3 29.2 87.0 16.0 140.4 1745.7 1736.7 45.0 5.5 93.2 3.1 1611.9 1644.5 11.8 23.3 5.9 109.6 29.4 1613.0 80.5 16.0 85.1 40.6 38.0 26.3 23.3 45.2 42.5 1564.5 25.7 37.7 5.7 1698.7 43.9 51.4 32.8 8.6 68.9 41.6 1770.4 0.0 0.0 0.9 0.0 20.7 1.3 0.3 0.1 0.0 0.1 0.2 0.0 0.1 0.1 5.8 0.0 0.2 0.4 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 1.4 0.0 0.1 0.1 0.3 64.9 0.0 0.0 0.9 0.0 0.0 0.0 0.3 0.4 0.0 0.1 0.2 0.1 0.2 0.1 0.0 0.2 0.2 0.0 0.1 0.0 0.2 0.2 0.0 3.6 0.3 0.2 0.2 0.1 0.1 0.0 0.1 1.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1824.7 1801.2 1490.8 1923.8 1745.7 1736.7 1611.9 1644.5 1613.0 1564.5 1698.7 1770.4 196.3 6.4 5.5 81.9 0.5 2.2 50.8 0.3 2.2 5.2 2.3 1.3 26.5 4.3 3.2 38.6 52.1 0.1 0.4 0.0 9.8 1.1 14.5 23.2 2.4 121.3 3.6 2.7 1.4 0.2 0.0 18.4 0.0 39.3 1.3 5.9 150.6 1.6 0.0 3.3 5.3 0.0 0.0 2.2 3.7 32.4 32.9 1.9 5.4 14.0 0.0 125.0 0.0 2.0 0.6 0.3 0.0 11.7 1.3 7.3 0.2 4.5 2.3 50.2 6.6 6.6 10.4 0.7 0.4 0.4 2.7 0.0 1.0 0.5 0.0 2.2 FBXL4 "FBL4, FBL5" ENSG00000112234 "F-box and leucine rich repeat protein 4" Q9UKA2 6 98868535-98948006 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 97.0;Oligodendrocytes: 94.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029140, CAB033362" Approved Supported "Nuclear speckles" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 1: Thyroid gland - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 68: Oligodendrocytes - Mixed function" "Nuclear speckles" "CAB033362: AB_2103974, HPA029140: AB_10611967" "unprognostic (1.24e-1)" "unprognostic (5.10e-2)" "unprognostic (1.10e-2)" "unprognostic (1.42e-1)" "unprognostic (3.34e-2)" "unprognostic (1.66e-1)" "unprognostic (2.03e-1)" "unprognostic (3.10e-1)" "unprognostic (2.79e-1)" "unprognostic (2.68e-1)" "unprognostic (4.53e-2)" "unprognostic (1.14e-1)" "unprognostic (1.05e-2)" "unprognostic (1.09e-1)" "unprognostic (1.70e-1)" "unprognostic (1.65e-1)" "unprognostic (2.62e-1)" 5.8 8.0 5.9 5.3 8.4 5.1 7.7 7.6 5.5 7.0 5.5 6.2 5.9 6.9 11.2 5.3 7.7 6.6 5.9 4.6 7.1 13.1 15.7 5.9 6.1 8.0 8.3 8.2 9.4 12.7 4.8 6.8 8.4 8.0 6.9 5.1 9.9 6.6 9.4 5.7 5.8 6.2 7.2 5.3 7.4 4.1 7.4 9.0 12.2 7.2 6.4 5.7 5.3 11.0 5.7 9.0 7.6 10.2 12.5 22.8 8.2 12.7 10.7 7.3 10.3 4.1 10.7 13.1 11.5 10.6 12.8 8.1 8.8 9.2 11.1 21.4 7.2 9.3 6.2 9.4 9.7 11.5 8.9 13.0 16.4 6.6 18.4 20.4 9.5 10.2 12.6 10.1 13.4 5.6 4.3 5.5 4.0 7.5 5.5 14.6 5.2 10.7 13.9 8.2 9.5 7.7 6.7 8.9 12.2 9.2 6.6 8.2 13.3 8.4 3.7 11.9 9.3 3.4 3.4 5.5 10.5 10.4 10.2 18.4 4.7 13.0 4.6 4.5 6.1 7.1 4.6 4.6 3.8 5.7 5.9 5.6 5.9 4.3 6.0 2.5 6.1 3.9 5.9 8.4 7.6 5.5 4.6 7.1 8.0 8.3 8.4 7.2 7.4 11.0 12.2 19.2 11.9 42.7 14.2 9.7 8.2 9.0 12.0 14.9 9.1 8.3 16.2 5.7 8.8 36.8 22.9 10.1 9.5 9.8 19.6 9.7 5.4 10.6 14.5 10.8 7.2 20.2 46.9 11.0 10.7 13.7 14.3 7.9 8.9 20.8 11.4 19.4 8.9 10.1 58.3 13.7 8.2 12.3 6.4 2.1 19.0 11.8 5.4 41.2 14.9 10.6 12.3 97.0 94.4 7.5 9.8 12.8 8.8 13.9 12.5 11.8 11.3 13.3 13.1 12.7 10.0 4.1 6.4 12.4 8.5 9.9 9.3 16.9 10.4 8.2 FEV Pet-1 ENSG00000163497 "FEV transcription factor, ETS family member" Q99581 2 218981087-218985184 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "brain: 70.8" "Cell type enriched" "Detected in some" 32 "Enteroendocrine cells: 744.9" "Group enriched" "Detected in some" 10 "pancreatic cancer: 3.0;prostate cancer: 9.9;stomach cancer: 2.4" "Group enriched" "Detected in many" 7 "midbrain: 70.8;pons: 20.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HMC-1: 35.5;SH-SY5Y: 43.8" "Region enhanced" "Detected in single" "midbrain: 1.9" "Group enriched" "Detected in some" 5 "midbrain: 4.8;pons: 2.7" HPA067679 Supported Supported "Nuclear speckles" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Nuclear speckles" "HPA067679: AB_2685884" "unprognostic (4.58e-1)" "unprognostic (1.60e-1)" "unprognostic (7.21e-2)" "prognostic favorable (4.85e-4)" "unprognostic (2.87e-1)" "unprognostic (3.96e-1)" "unprognostic (1.52e-1)" "unprognostic (2.15e-1)" 0.1 2.3 0.0 0.0 1.7 0.0 0.0 0.0 0.6 0.0 0.0 1.2 4.3 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.1 0.1 0.0 0.0 0.0 6.2 70.8 0.0 1.3 0.0 2.6 0.0 20.1 2.2 1.8 0.4 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.0 3.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 35.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.1 43.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.6 0.6 0.1 6.2 70.8 20.1 0.1 0.3 0.2 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 1.2 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.1 744.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 22.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.2 6.0 0.0 0.0 3.4 1.2 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.4 0.1 FIBP FGFIBP ENSG00000172500 "FGF1 intracellular binding protein" O43427 11 65883740-65888531 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 608.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011729 Approved Supported "Nuclear speckles" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear speckles" "HPA011729: AB_1848579" "unprognostic (1.70e-1)" "unprognostic (6.06e-2)" "unprognostic (1.06e-1)" "unprognostic (3.35e-1)" "unprognostic (1.37e-1)" "unprognostic (4.49e-2)" "prognostic unfavorable (1.74e-4)" "unprognostic (2.23e-1)" "unprognostic (2.95e-1)" "unprognostic (3.10e-3)" "unprognostic (2.13e-1)" "unprognostic (1.29e-1)" "unprognostic (5.50e-2)" "unprognostic (2.39e-1)" "unprognostic (3.18e-1)" "unprognostic (1.83e-2)" "unprognostic (4.89e-2)" 34.1 48.4 48.0 26.8 49.0 32.2 33.0 48.0 55.1 31.1 41.8 30.8 30.4 35.9 29.4 35.6 37.2 22.3 56.8 51.0 50.5 48.3 37.1 31.6 35.6 53.3 47.6 28.6 39.0 32.8 31.2 25.1 54.3 30.6 27.3 19.8 27.9 24.6 53.6 45.7 35.3 30.9 46.6 43.3 37.7 64.9 49.9 40.3 35.9 56.1 42.9 29.7 28.3 47.8 61.0 86.9 48.3 118.6 72.8 91.2 35.9 54.8 110.9 74.3 62.0 36.1 83.1 79.7 98.2 124.1 35.9 65.2 48.5 121.0 48.1 93.7 62.2 77.3 84.1 54.7 99.8 100.7 64.4 73.8 68.3 54.1 114.4 60.0 93.7 61.5 27.4 139.4 98.9 198.2 78.9 88.0 47.8 61.5 130.7 104.9 45.6 196.3 88.5 79.6 87.8 80.4 60.3 110.6 110.5 32.5 113.0 58.1 86.3 79.7 66.4 130.9 40.3 73.8 87.6 48.4 101.1 73.6 30.7 123.5 121.2 98.9 71.1 136.9 74.4 100.7 67.2 64.9 164.7 83.1 52.7 57.0 20.4 101.1 150.0 84.1 100.6 109.4 48.0 49.0 48.0 55.1 51.0 50.5 53.3 47.6 54.3 46.6 49.9 47.8 55.8 12.8 28.0 4.9 57.0 47.3 51.7 105.7 38.7 47.7 66.9 85.6 44.7 42.9 55.7 44.1 31.3 79.4 41.1 61.6 93.9 114.2 176.7 45.3 59.8 52.6 93.5 39.1 7.1 149.3 125.7 50.3 37.2 39.6 67.2 68.6 45.3 36.5 115.0 42.1 7.3 49.2 57.0 75.3 75.9 608.0 36.1 67.9 51.6 3.7 129.3 47.1 101.0 3.5 5.6 98.9 68.8 39.5 60.1 56.1 185.8 150.1 54.9 52.8 19.7 39.2 77.2 100.5 84.0 51.5 52.1 71.8 54.6 79.6 58.8 61.5 FLT4 "PCL, VEGFR-3, VEGFR3" ENSG00000037280 "Fms related receptor tyrosine kinase 4" P35916 5 180601506-180649624 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Adipocytes: 27.4;Endothelial cells: 27.1;Extravillous trophoblasts: 37.1;Hepatic stellate cells: 64.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "MAIT T-cell: 3.8" "Lineage enriched" "Detected in single" 31 "T-cells: 3.8" "Cell line enhanced" "Detected in some" "AN3-CA: 10.1;BEWO: 12.4;HEK 293: 15.6;HL-60: 9.5;HUVEC TERT2: 9.9;JURKAT: 12.3;T-47d: 14.6;TIME: 15.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000099, HPA046519, HPA067906, HPA074389" Approved Supported "Nuclear speckles,Plasma membrane,Cell Junctions" "Secreted to blood" NA NA 20000000 290000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 6: T47d - Mammary gland" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles, Plasma membrane" "Cell Junctions" "CAB000099: , HPA046519: AB_2732527, HPA067906: AB_2732775, HPA074389: " "unprognostic (7.35e-2)" "unprognostic (1.63e-1)" "unprognostic (9.45e-3)" "unprognostic (3.81e-1)" "unprognostic (9.26e-2)" "unprognostic (3.20e-3)" "unprognostic (1.13e-2)" "unprognostic (1.80e-2)" "unprognostic (2.19e-1)" "unprognostic (1.70e-1)" "unprognostic (2.13e-2)" "unprognostic (3.69e-1)" "unprognostic (1.88e-2)" "unprognostic (9.41e-3)" "unprognostic (1.83e-1)" "unprognostic (8.26e-2)" "unprognostic (1.32e-1)" 17.2 11.3 3.5 4.7 4.6 0.8 14.7 2.6 3.4 9.0 2.6 4.9 2.8 8.0 3.0 4.4 9.8 3.8 9.7 5.1 2.6 20.1 6.2 16.9 5.5 3.4 3.0 4.5 2.0 2.3 7.8 6.4 3.6 5.6 1.3 0.3 2.0 2.5 4.7 4.0 7.2 4.1 2.8 17.6 3.5 3.1 4.2 1.0 25.7 4.1 1.4 5.6 5.5 2.7 0.1 2.5 3.2 10.1 0.0 0.0 12.4 0.3 0.1 0.0 0.0 0.4 0.3 0.3 0.9 0.1 0.6 0.4 3.4 0.2 0.3 0.1 15.6 1.2 0.5 0.5 0.1 9.5 0.3 0.2 0.1 0.2 0.4 0.3 9.9 12.3 0.4 0.4 2.1 5.6 0.1 0.5 7.0 0.3 0.6 8.2 0.1 0.1 0.1 0.3 0.3 1.1 0.1 0.2 0.1 3.1 14.6 0.3 15.7 0.2 6.9 0.2 0.1 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.5 0.0 3.8 0.0 0.2 0.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 3.5 4.6 2.6 3.4 5.1 2.6 3.4 3.0 3.6 2.8 4.2 2.7 27.4 0.0 1.7 0.7 0.7 0.9 0.2 0.0 1.2 0.2 1.4 1.4 4.5 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.1 0.1 27.1 0.0 0.0 0.2 0.0 37.1 0.8 0.0 0.1 2.5 2.4 64.6 0.6 1.2 0.0 0.1 0.0 0.0 3.3 0.8 0.7 0.3 0.6 0.0 3.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.2 0.0 0.7 0.7 0.1 5.2 0.1 1.1 1.0 1.8 0.2 0.0 0.1 FOXO4 "AFX1, MLLT7" ENSG00000184481 "Forkhead box O4" P98177 X 71095851-71103532 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors" "Cell cycle, Differentiation, Myogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 116.5" "Group enriched" "Detected in many" 5 "Cytotrophoblasts: 260.7;Syncytiotrophoblasts: 307.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in many" 6 "BEWO: 159.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039560, HPA040232" Enhanced Supported "Nuclear speckles,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nuclear speckles" Cytosol "HPA039560: AB_2676572, HPA040232: AB_2676894" "unprognostic (4.64e-2)" "unprognostic (2.94e-2)" "unprognostic (2.19e-1)" "unprognostic (2.49e-1)" "unprognostic (4.79e-2)" "prognostic favorable (4.61e-4)" "unprognostic (1.09e-1)" "unprognostic (3.20e-2)" "unprognostic (1.58e-1)" "unprognostic (7.18e-2)" "unprognostic (2.13e-2)" "unprognostic (8.16e-2)" "prognostic favorable (3.46e-4)" "unprognostic (2.45e-2)" "unprognostic (2.07e-1)" "unprognostic (1.20e-1)" "unprognostic (1.75e-3)" 15.8 33.6 73.9 6.5 80.6 22.0 13.9 58.9 68.7 12.9 43.1 22.1 11.0 17.1 16.4 12.0 17.6 9.4 18.2 58.3 61.8 9.4 7.2 10.0 7.1 71.7 70.5 23.2 12.7 16.0 7.0 116.5 65.3 14.3 8.0 7.5 16.7 19.2 67.3 15.1 14.3 8.2 62.3 13.9 13.5 17.3 68.8 14.5 10.9 49.4 6.4 17.2 13.2 81.6 4.6 1.2 3.4 4.9 7.9 5.7 159.1 3.4 3.9 1.8 4.5 3.3 6.5 5.9 4.7 4.5 1.9 2.1 8.8 4.2 2.2 6.0 13.7 8.5 27.3 5.0 4.8 4.9 6.9 5.1 9.7 1.7 1.1 7.9 4.7 8.4 17.5 12.5 0.8 0.9 8.6 8.0 16.9 11.5 5.6 5.7 8.5 10.1 3.0 2.6 2.8 7.3 7.1 1.1 8.3 24.7 1.9 3.1 4.3 1.1 2.3 8.3 0.8 7.7 4.3 1.0 4.3 13.6 1.3 0.0 0.1 1.0 0.2 0.1 0.0 0.2 0.1 0.2 0.0 0.2 0.1 0.4 0.9 0.2 0.1 0.0 0.3 0.3 73.9 80.6 58.9 68.7 58.3 61.8 71.7 70.5 65.3 62.3 68.8 81.6 10.1 0.0 2.7 0.3 3.8 5.4 3.9 0.6 9.1 1.3 8.2 7.7 6.6 5.7 1.5 9.2 4.2 260.7 6.5 20.6 1.9 2.7 0.3 3.2 2.8 6.1 6.1 17.7 0.8 3.0 24.3 4.0 5.1 3.1 2.5 3.1 5.0 2.9 22.3 1.7 0.8 12.2 0.0 7.1 5.2 1.4 6.8 4.4 3.6 1.0 2.6 4.4 4.1 1.0 2.2 3.1 8.6 15.4 7.3 2.5 17.1 4.4 1.5 0.8 6.6 4.0 3.8 0.6 0.4 6.0 3.4 307.8 7.0 48.3 7.4 3.8 FYTTD1 "DKFZp761B1514, UIF" ENSG00000122068 "Forty-two-three domain containing 1" Q96QD9 3 197737179-197787596 "Predicted intracellular proteins" "mRNA transport, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054474, HPA074880" Enhanced Supported "Nuclear speckles" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nuclear speckles" "HPA054474: , HPA074880: " "unprognostic (3.61e-2)" "unprognostic (6.01e-2)" "unprognostic (4.88e-2)" "prognostic unfavorable (3.08e-4)" "unprognostic (2.33e-2)" "unprognostic (3.80e-1)" "unprognostic (3.69e-2)" "unprognostic (9.57e-3)" "unprognostic (4.44e-2)" "unprognostic (1.66e-1)" "unprognostic (5.04e-3)" "unprognostic (8.74e-2)" "unprognostic (8.49e-3)" "unprognostic (3.40e-2)" "unprognostic (3.36e-1)" "unprognostic (3.29e-1)" "unprognostic (3.15e-1)" 29.7 20.9 12.1 27.1 12.6 39.2 26.6 16.1 14.6 24.8 9.1 19.9 16.7 30.4 19.6 43.9 19.1 24.4 41.3 12.1 14.9 25.7 28.9 23.6 32.4 12.4 13.9 27.5 36.4 28.7 12.6 33.5 13.0 25.1 21.6 33.8 18.2 28.8 92.6 27.1 19.3 34.9 12.8 26.3 18.2 41.1 13.3 34.1 29.6 67.0 37.7 33.6 16.9 14.9 104.5 22.6 43.7 41.7 50.1 55.3 13.4 50.0 50.8 75.4 61.4 35.3 34.8 66.4 177.1 59.3 40.0 36.7 55.5 51.0 79.8 14.5 24.9 99.8 32.9 16.1 48.9 75.1 46.5 40.0 64.6 40.8 58.3 52.1 60.4 36.8 45.9 139.0 67.6 86.9 82.2 18.1 9.6 45.1 41.2 74.9 53.6 47.4 54.8 67.3 82.4 35.7 76.8 60.0 56.4 31.8 141.2 39.1 54.0 38.5 38.1 49.0 53.6 83.5 137.2 79.3 40.8 106.4 40.6 59.2 26.9 26.5 32.4 31.8 40.7 20.0 30.7 35.9 29.9 18.9 33.4 32.2 8.5 64.6 31.0 16.9 30.2 45.7 12.1 12.6 16.1 14.6 12.1 14.9 12.4 13.9 13.0 12.8 13.3 14.9 60.6 35.3 27.2 14.7 78.5 82.3 46.6 24.3 42.7 35.1 47.0 34.4 109.7 25.8 30.1 47.8 31.3 24.4 63.9 19.0 90.1 35.5 21.7 27.3 58.9 55.2 56.4 25.2 23.7 36.1 27.5 53.7 30.1 42.6 66.6 29.4 36.4 50.7 38.0 45.4 19.6 23.7 28.5 48.6 67.8 18.3 32.0 54.8 51.6 22.5 108.6 41.8 82.4 19.6 23.0 34.3 16.5 37.2 65.4 74.5 17.1 51.1 44.6 45.2 39.5 45.8 63.1 96.3 90.7 54.0 91.1 50.1 60.7 51.9 20.0 63.6 GADD45A "DDIT1, GADD45" ENSG00000116717 "Growth arrest and DNA damage inducible alpha" P24522 1 67685201-67688334 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, Growth arrest" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 240.5" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 858.9;Basal prostatic cells: 2807.1;Glandular and luminal cells: 982.6;Urothelial cells: 1740.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 48.4" "Group enriched" "Detected in all" 5 "granulocytes: 48.4;T-cells: 18.6" "Cell line enhanced" "Detected in all" "HHSteC: 365.9;hTERT-HME1: 577.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053420 Supported "Nuclear speckles" NA Yes "Cluster 2: Granulocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Nuclear speckles" "HPA053420: AB_2682144" "unprognostic (1.36e-2)" "unprognostic (3.29e-2)" "unprognostic (9.58e-2)" "unprognostic (3.76e-3)" "unprognostic (5.81e-2)" "unprognostic (1.36e-2)" "unprognostic (1.57e-3)" "unprognostic (2.80e-3)" "unprognostic (1.42e-1)" "unprognostic (6.26e-2)" "unprognostic (3.43e-2)" "unprognostic (5.21e-2)" "prognostic favorable (8.06e-6)" "unprognostic (6.11e-2)" "unprognostic (2.89e-1)" "unprognostic (3.43e-3)" "unprognostic (1.93e-1)" 122.0 15.9 21.0 20.0 24.7 136.2 83.7 19.2 27.5 65.6 22.3 29.6 24.8 69.5 23.3 39.2 42.3 44.2 62.2 20.8 24.0 147.2 164.9 75.0 13.7 34.7 26.8 49.6 20.2 19.5 19.1 22.2 24.6 25.6 21.2 19.0 32.4 36.9 240.5 57.9 32.2 38.3 18.6 26.8 53.2 12.3 25.3 30.7 73.8 26.4 16.8 50.4 44.4 28.7 138.6 9.7 22.3 7.5 44.8 43.9 219.8 239.5 122.6 88.5 96.7 50.8 25.3 61.1 71.4 42.0 206.6 85.3 3.0 219.6 164.5 44.9 23.6 75.7 24.0 51.8 365.9 22.5 7.5 76.7 117.8 107.7 577.7 41.5 61.0 15.2 165.6 109.9 104.5 4.8 7.2 27.3 29.8 19.3 96.3 16.4 177.2 67.9 44.2 110.5 102.7 17.1 51.9 15.2 158.3 79.7 2.6 23.2 61.6 85.7 111.6 89.3 165.7 267.3 54.9 106.8 37.8 11.1 86.3 23.6 5.7 48.4 6.3 2.8 5.3 2.3 4.4 5.3 2.6 1.5 1.2 2.0 8.2 6.5 2.0 4.1 18.6 8.7 21.0 24.7 19.2 27.5 20.8 24.0 34.7 26.8 24.6 18.6 25.3 28.7 402.5 64.1 19.0 6.8 51.2 858.9 2807.1 273.2 225.3 45.1 56.7 100.6 190.5 47.1 155.8 103.0 10.4 24.6 85.1 175.3 236.7 264.4 1.6 410.7 250.6 176.6 131.7 116.2 6.1 253.6 117.8 177.0 87.7 982.6 44.5 18.9 74.6 110.1 18.6 26.9 7.0 99.6 122.1 23.5 290.6 4.0 38.2 94.7 158.3 7.5 273.2 30.3 12.3 6.6 1.0 367.3 202.0 64.7 116.8 786.2 101.4 530.0 135.1 72.8 52.6 136.0 201.6 3.7 18.8 365.2 390.8 17.6 139.5 88.6 70.3 1740.4 GCAT KBL ENSG00000100116 "Glycine C-acetyltransferase" O75600 22 37807905-37817176 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 140.2" "Cell type enhanced" "Detected in many" "Distal tubular cells: 80.3;Hepatocytes: 66.1;Proximal tubular cells: 163.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020460, HPA063924" Approved Supported "Nucleoplasm,Nuclear speckles,Mitochondria" Yes No "Cluster 20: T-cells - T-cell receptor" "Cluster 22: Non-specific - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Nuclear speckles, Mitochondria" "HPA020460: AB_1849548, HPA063924: " "unprognostic (1.61e-1)" "unprognostic (1.80e-2)" "unprognostic (8.38e-2)" "unprognostic (1.05e-1)" "unprognostic (1.10e-2)" "unprognostic (4.17e-2)" "unprognostic (2.40e-1)" "unprognostic (1.37e-2)" "unprognostic (3.56e-2)" "unprognostic (2.76e-3)" "unprognostic (1.12e-1)" "unprognostic (2.51e-1)" "unprognostic (1.36e-3)" "unprognostic (8.00e-2)" "unprognostic (1.97e-1)" "unprognostic (4.73e-3)" "unprognostic (3.99e-1)" 6.6 15.7 25.1 3.2 24.8 14.1 6.5 26.2 33.3 6.3 22.5 7.3 4.9 7.8 3.0 17.0 6.0 5.0 43.4 26.1 25.0 13.0 53.3 5.6 2.8 25.9 27.4 9.0 140.2 6.0 9.7 2.7 27.8 22.8 4.9 2.2 13.3 6.8 19.5 8.1 5.4 4.2 24.4 1.5 13.2 10.3 27.9 4.3 16.0 19.1 3.1 7.1 7.0 24.6 18.7 4.7 11.9 68.2 24.0 19.4 8.4 25.9 26.9 19.2 16.3 10.5 2.1 5.8 11.8 11.7 11.3 10.6 11.9 18.3 4.3 2.6 21.9 12.9 15.0 42.5 39.0 23.0 16.4 22.8 10.9 12.7 27.7 6.2 16.0 23.0 33.2 6.6 9.2 16.2 24.3 42.3 5.0 28.8 19.0 25.2 2.5 34.4 24.6 14.3 24.5 16.7 20.0 32.3 13.9 4.2 25.8 11.1 11.8 19.3 10.6 12.9 9.2 21.9 11.5 12.1 13.3 21.1 20.5 0.1 0.6 0.4 0.7 0.7 0.3 0.1 1.6 0.5 1.3 0.0 3.5 1.4 0.3 1.3 0.4 1.3 1.7 1.4 25.1 24.8 26.2 33.3 26.1 25.0 25.9 27.4 27.8 24.4 27.9 24.6 3.5 6.4 15.4 9.8 2.8 7.8 18.5 11.2 12.5 8.9 18.6 17.4 54.6 11.5 9.4 11.0 4.2 15.7 0.7 13.1 80.3 7.2 4.1 9.9 8.1 5.5 2.4 22.7 5.0 10.3 19.6 9.8 15.3 16.7 8.9 17.6 5.0 66.1 4.7 8.4 4.7 32.3 8.2 2.9 1.3 7.7 3.7 2.1 21.4 1.0 1.0 25.1 1.0 6.6 4.1 5.4 8.7 9.8 2.0 19.1 8.6 163.8 6.4 2.2 6.6 4.8 30.1 12.6 33.2 19.6 6.0 27.8 3.0 27.8 24.0 14.4 GCNT1 "C2GNT, NACGT2, NAGCT2" ENSG00000187210 "Glucosaminyl (N-acetyl) transferase 1" Q02742 9 76419850-76651203 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 49.9;parathyroid gland: 84.1;stomach 1: 39.0;thyroid gland: 21.5" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 93.8;Kupffer cells: 42.2;Proximal enterocytes: 40.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 21.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 46.2;HSkMC: 39.4;U-2197: 33.9" "Group enriched" "Detected in all" 6 "cerebellum: 7.6;olfactory bulb: 24.9" "Low region specificity" "Detected in all" "HPA003522, HPA003523, HPA031151" Uncertain Supported "Nuclear speckles" NA NA 84000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 18: U-2197 - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nuclear speckles" "HPA003522: , HPA003523: , HPA031151: AB_10602904" "unprognostic (3.14e-1)" "unprognostic (2.01e-1)" "unprognostic (2.19e-1)" "prognostic favorable (8.44e-4)" "unprognostic (5.53e-2)" "unprognostic (2.41e-1)" "unprognostic (1.65e-2)" "unprognostic (3.37e-2)" "unprognostic (2.40e-1)" "unprognostic (2.63e-1)" "unprognostic (1.90e-1)" "unprognostic (3.06e-1)" "unprognostic (3.02e-3)" "unprognostic (4.21e-1)" "unprognostic (2.00e-1)" "unprognostic (2.80e-1)" "prognostic unfavorable (4.96e-4)" 4.0 0.8 1.8 5.0 2.2 5.1 4.6 4.8 1.7 10.6 1.3 8.7 49.9 5.9 0.7 1.8 1.5 2.9 1.2 2.0 0.9 0.9 1.9 4.2 6.7 1.0 1.0 0.7 2.1 84.1 0.9 2.9 1.0 6.3 9.3 0.1 3.8 1.3 0.3 1.1 32.3 4.8 1.0 7.3 39.0 1.6 1.5 3.0 21.5 0.7 4.7 2.2 0.8 1.4 4.7 0.4 0.3 0.1 5.5 26.5 6.7 18.8 8.4 15.0 10.5 4.7 1.1 3.3 1.8 14.1 2.9 4.0 9.5 7.8 16.6 2.3 1.6 8.2 0.4 0.8 46.2 6.0 2.7 39.4 2.0 14.5 15.5 12.2 13.9 4.1 0.0 3.2 15.1 7.1 3.2 9.7 8.8 11.9 1.1 5.3 9.3 1.6 17.5 8.3 2.0 0.0 2.3 2.5 0.1 6.6 0.0 4.1 5.6 9.3 5.9 33.9 8.4 4.7 0.9 0.0 18.7 10.1 2.3 6.1 3.2 21.6 1.5 7.8 0.5 1.9 1.7 1.5 5.8 10.2 0.3 1.1 1.1 5.8 7.3 2.8 2.5 2.1 1.8 2.2 4.8 1.7 2.0 0.9 1.0 1.0 1.0 1.0 1.5 1.4 2.9 0.0 1.7 2.0 8.3 0.9 5.0 34.4 0.6 0.0 8.8 4.2 1.0 0.0 15.6 3.7 0.0 2.1 10.7 16.6 0.0 1.0 20.1 15.1 4.2 5.1 27.6 17.9 11.8 24.3 27.1 3.4 93.8 24.6 10.8 0.6 6.4 0.3 8.1 0.0 1.7 21.3 16.2 42.2 8.5 12.9 0.0 18.6 1.8 15.0 6.7 0.1 8.2 0.5 0.8 12.9 14.5 1.2 2.2 6.8 40.7 1.4 17.0 0.4 0.0 0.9 1.8 1.8 3.3 1.0 0.3 19.0 10.6 0.2 38.4 1.5 GPATCH2 "CT110, FLJ10252, GPATC2, Pfa1, PPP1R30" ENSG00000092978 "G-patch domain containing 2" Q9NW75 1 217426992-217631090 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 171.0;Rod photoreceptor cells: 144.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027181, HPA027322" Uncertain Supported "Nuclear speckles" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 30: Epithelial cell lines - Translation" "Cluster 9: Photoreceptor cells - Phototransduction" "Nuclear speckles" "HPA027181: AB_10602601, HPA027322: AB_1848645" "unprognostic (3.27e-1)" "unprognostic (2.66e-1)" "unprognostic (1.29e-1)" "unprognostic (2.04e-1)" "unprognostic (3.27e-2)" "unprognostic (5.13e-2)" "unprognostic (6.50e-2)" "unprognostic (1.28e-1)" "unprognostic (6.24e-3)" "unprognostic (2.46e-2)" "unprognostic (1.53e-1)" "unprognostic (2.03e-1)" "prognostic unfavorable (9.99e-6)" "unprognostic (3.52e-1)" "unprognostic (2.50e-2)" "unprognostic (1.53e-2)" "unprognostic (5.41e-2)" 4.1 4.2 3.5 4.1 4.0 3.2 7.1 3.0 4.8 5.9 6.3 4.3 4.9 6.5 5.9 5.5 5.0 6.1 3.5 4.3 5.1 5.2 4.9 4.2 5.1 2.9 3.2 4.8 3.9 6.9 4.4 6.3 3.1 6.9 4.6 5.7 3.7 5.3 6.6 4.4 4.8 5.1 3.2 4.8 4.8 6.2 4.5 6.3 6.6 2.9 5.6 6.1 4.1 3.8 8.4 9.4 9.9 7.8 8.6 8.7 8.2 7.7 9.4 10.5 9.9 8.3 10.6 8.9 7.6 6.7 6.5 9.7 11.2 9.1 12.2 6.6 6.4 5.9 7.9 5.3 10.6 9.0 6.7 7.7 13.0 12.3 20.0 9.1 7.3 9.8 14.7 0.1 7.7 7.9 12.2 6.4 18.0 6.7 10.2 5.9 22.7 10.7 7.4 17.9 11.6 16.5 13.7 12.5 10.7 15.5 11.7 8.7 7.5 9.8 6.8 13.9 7.2 9.0 6.8 8.4 7.4 5.9 7.1 4.1 3.1 1.1 2.6 1.9 1.8 2.6 3.0 1.8 3.4 2.8 2.7 2.4 0.4 2.7 2.9 5.0 2.9 1.5 3.5 4.0 3.0 4.8 4.3 5.1 2.9 3.2 3.1 3.2 4.5 3.8 17.5 12.8 15.9 43.8 19.4 15.6 16.1 13.4 14.8 55.4 27.2 27.9 14.4 21.5 15.3 18.4 171.0 20.8 24.5 22.4 13.7 20.4 62.6 41.3 36.4 20.5 20.8 12.0 113.1 18.0 22.2 23.0 19.4 24.0 9.5 32.9 20.7 12.4 15.7 50.5 60.5 21.5 18.3 9.2 9.2 22.8 19.9 16.6 5.4 39.4 17.2 27.7 28.8 46.3 47.1 15.0 17.2 23.0 24.5 17.5 17.9 18.1 22.3 144.2 19.7 36.8 20.2 53.3 23.8 12.9 19.5 21.6 20.0 41.4 23.1 19.0 GRK5 GPRK5 ENSG00000198873 "G protein-coupled receptor kinase 5" P34947 10 119207571-119459745 "Enzymes, Predicted intracellular proteins" "Apoptosis, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 57.7;Microglial cells: 56.2;Sertoli cells: 59.2;Smooth muscle cells: 46.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 32.1;HUVEC TERT2: 24.9;OE19: 25.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025579, HPA046838" Approved Supported "Nuclear membrane,Nuclear speckles,Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 21: OE19 - Mitochondria" "Cluster 50: Fibroblasts - ECM organization" "Nuclear membrane, Nuclear speckles" "Plasma membrane" "CAB025579: , HPA046838: AB_2679833" "unprognostic (1.09e-1)" "unprognostic (3.47e-1)" "unprognostic (1.19e-1)" "unprognostic (6.02e-2)" "unprognostic (6.56e-2)" "unprognostic (3.74e-2)" "unprognostic (4.62e-2)" "unprognostic (3.69e-1)" "unprognostic (4.11e-1)" "unprognostic (1.06e-1)" "unprognostic (3.70e-1)" "unprognostic (2.32e-1)" "prognostic unfavorable (2.38e-7)" "unprognostic (1.10e-1)" "unprognostic (3.27e-2)" "unprognostic (1.55e-2)" "unprognostic (1.90e-2)" 38.4 18.0 4.2 5.9 5.0 2.7 24.6 5.0 4.6 18.8 3.5 26.3 10.0 21.1 3.5 12.6 19.6 5.7 48.8 4.0 5.1 14.2 12.9 65.6 7.8 3.9 3.6 35.0 4.7 21.3 13.3 8.3 3.9 14.1 4.9 1.0 7.8 4.0 11.9 11.5 25.8 7.3 3.3 37.0 27.5 4.1 4.9 6.2 19.6 9.7 6.8 19.4 18.1 3.5 3.7 2.3 5.4 5.7 11.8 11.0 1.6 7.1 32.1 4.1 2.3 1.7 5.4 3.9 1.6 11.1 7.5 0.9 2.3 7.7 2.7 15.4 2.0 0.7 4.6 7.0 8.2 0.2 2.0 1.5 1.1 8.5 1.2 5.2 24.9 2.4 0.4 3.7 1.5 0.7 3.8 3.5 0.8 25.8 5.2 1.3 0.8 0.9 0.6 1.5 1.8 4.9 2.4 1.1 7.0 3.0 0.1 0.9 7.8 2.3 1.6 14.6 2.8 0.9 4.4 2.4 4.9 4.4 2.4 0.4 1.5 2.9 2.0 1.4 0.1 3.8 3.0 1.6 0.9 4.0 4.5 2.0 2.1 0.1 0.5 0.0 4.0 1.7 4.2 5.0 5.0 4.6 4.0 5.1 3.9 3.6 3.9 3.3 4.9 3.5 32.6 57.7 3.7 3.6 19.7 1.7 0.7 0.5 1.2 3.9 2.3 2.0 19.4 0.0 1.3 3.7 0.0 3.7 13.3 0.4 0.0 1.1 18.7 0.4 5.1 28.4 4.8 0.0 17.7 3.1 15.8 35.7 18.8 1.0 4.5 7.8 24.7 2.2 4.4 1.7 36.5 0.8 6.1 15.5 6.3 4.9 4.4 14.2 7.2 56.2 3.6 0.0 19.6 14.1 5.7 2.4 1.2 4.5 10.2 0.7 4.9 0.6 0.8 0.9 59.2 18.2 46.5 1.3 2.1 0.7 2.4 13.1 14.1 4.6 0.5 0.9 GSC ENSG00000133937 "Goosecoid homeobox" P56915 14 94768223-94770113 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 3.8;breast: 6.8" "Cell type enhanced" "Detected in some" "Adipocytes: 3.5;Breast myoepithelial cells: 2.2;Ductal cells: 3.0;Exocrine glandular cells: 2.4;Fibroblasts: 9.2;Langerhans cells: 2.3;Skeletal myocytes: 2.6;Smooth muscle cells: 4.6" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 9 "hypothalamus: 1.4" "Immune cell enriched" "Detected in single" 8 "gdT-cell: 3.6" "Lineage enriched" "Detected in single" 18 "T-cells: 3.6" "Cell line enhanced" "Detected in some" "AN3-CA: 1.3;HEK 293: 2.0;MCF7: 3.2;REH: 3.3;SH-SY5Y: 3.5;T-47d: 2.5;U-251 MG: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "CAB079923, CAB079924" Supported "Nucleoplasm,Nuclear speckles,Actin filaments" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 14: REH - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nuclear speckles" "Actin filaments" "CAB079923: , CAB079924: " "unprognostic (2.11e-2)" "unprognostic (1.04e-1)" "unprognostic (3.15e-2)" "unprognostic (5.11e-2)" "unprognostic (2.49e-1)" "unprognostic (3.70e-3)" "unprognostic (1.82e-3)" "unprognostic (3.87e-2)" "unprognostic (3.41e-1)" "unprognostic (2.74e-1)" "unprognostic (1.39e-1)" "unprognostic (2.28e-1)" "unprognostic (5.18e-10)" "unprognostic (4.96e-2)" "unprognostic (1.31e-1)" "unprognostic (1.52e-1)" "unprognostic (1.16e-1)" 3.8 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.1 0.4 0.1 0.1 0.2 0.0 0.1 0.4 0.0 0.5 0.0 1.4 0.1 0.0 0.0 0.3 0.1 0.1 0.1 0.6 0.1 0.4 0.0 0.0 0.7 0.0 0.0 0.9 0.5 1.2 0.8 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.2 1.6 2.2 0.1 0.3 0.2 0.0 0.0 0.2 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.3 0.0 0.0 0.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 3.2 0.2 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.1 2.5 0.0 0.0 0.0 0.6 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.1 0.0 0.2 0.4 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.1 0.0 0.0 0.1 0.0 3.5 0.0 0.0 0.0 0.1 0.6 0.3 0.0 0.0 0.0 1.0 2.2 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 3.0 0.1 0.3 0.1 0.4 0.0 0.0 0.0 2.4 0.0 9.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 0.0 0.2 0.0 0.0 0.6 0.0 1.0 0.0 0.0 0.7 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 2.6 4.6 0.0 1.2 0.0 0.9 0.0 0.4 0.0 0.0 0.1 GTF2H2 "BTF2, BTF2P44, p44, T-BTF2P44, TFIIH" ENSG00000145736 "General transcription factor IIH subunit 2" Q13888 5 71032670-71067689 "Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Daudi: 18.5;RPTEC TERT1: 19.1" HPA047001 Supported "Nuclear speckles" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nuclear speckles" "HPA047001: AB_2679899" "unprognostic (7.40e-3)" "unprognostic (4.71e-1)" "unprognostic (6.31e-2)" "unprognostic (2.99e-1)" "unprognostic (1.62e-1)" "unprognostic (3.07e-1)" "unprognostic (1.29e-2)" "unprognostic (4.69e-2)" "unprognostic (2.08e-1)" "unprognostic (2.22e-3)" "unprognostic (3.74e-1)" "unprognostic (3.06e-1)" "unprognostic (3.67e-2)" "unprognostic (3.93e-2)" "unprognostic (2.43e-1)" "unprognostic (1.87e-3)" "unprognostic (1.62e-1)" 3.1 2.9 0.6 1.1 0.7 1.1 2.8 1.1 1.7 3.9 0.4 4.6 0.2 3.8 2.0 2.6 3.4 1.2 2.7 0.6 0.9 3.6 3.4 2.8 4.8 0.8 0.9 3.4 4.3 1.1 2.6 0.9 1.0 2.3 1.0 1.7 2.8 0.6 3.5 1.9 2.9 5.1 0.6 2.8 2.9 3.7 0.9 1.4 3.5 0.0 0.3 2.6 3.0 1.2 4.8 0.0 4.2 0.0 11.0 12.8 13.9 0.5 0.2 0.3 0.7 12.0 0.4 18.5 8.4 10.2 6.1 3.1 0.6 0.1 0.3 15.0 14.0 8.7 0.2 0.9 12.3 0.4 0.0 0.0 2.7 0.4 0.0 2.4 0.0 0.1 0.2 3.3 0.0 7.3 5.6 6.0 0.1 0.1 0.0 6.6 2.6 11.1 19.1 0.0 0.4 4.6 12.1 1.4 11.5 0.3 7.7 8.0 4.2 5.3 1.1 0.7 8.7 0.2 0.8 4.7 0.1 0.8 10.1 0.2 0.5 0.2 0.6 0.3 0.2 0.5 0.7 0.5 0.3 0.8 0.7 0.5 2.1 0.3 0.3 0.3 0.0 0.3 0.6 0.7 1.1 1.7 0.6 0.9 0.8 0.9 1.0 0.6 0.9 1.2 6.9 16.0 27.0 6.8 17.6 16.6 23.5 17.5 7.4 23.3 14.9 8.1 16.7 28.6 18.7 12.9 39.6 37.3 9.6 8.4 46.9 19.1 5.4 17.0 17.7 12.6 12.0 15.2 10.0 20.5 17.5 14.6 7.1 17.7 6.3 25.5 14.6 12.5 15.0 25.2 10.2 5.9 14.2 15.0 9.9 7.0 24.2 11.0 14.2 4.7 7.9 10.6 9.2 9.0 11.0 16.7 7.5 13.2 14.6 23.7 8.9 22.5 22.7 39.7 26.3 14.1 12.5 60.3 55.9 6.9 12.5 9.6 15.3 15.5 9.1 18.7 GTF2H4 "P52, TFB2, TFIIH" ENSG00000213780 "General transcription factor IIH subunit 4" Q92759 6 30908207-30914106 "Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 12.5;Gastric mucus-secreting cells: 9.7;granulocytes: 7.0;Plasma cells: 9.2;Squamous epithelial cells: 13.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA074336 Supported "Nuclear speckles" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nuclear speckles" "HPA074336: AB_2686679" "unprognostic (7.05e-2)" "unprognostic (1.79e-1)" "unprognostic (3.07e-1)" "unprognostic (4.79e-4)" "unprognostic (7.42e-2)" "unprognostic (1.11e-1)" "unprognostic (5.54e-2)" "unprognostic (1.58e-1)" "unprognostic (1.84e-1)" "unprognostic (2.36e-2)" "unprognostic (5.66e-4)" "unprognostic (7.74e-3)" "prognostic unfavorable (4.08e-4)" "unprognostic (1.22e-1)" "unprognostic (9.53e-2)" "unprognostic (6.06e-2)" "unprognostic (2.07e-2)" 12.6 11.1 5.4 6.6 6.6 4.7 11.4 6.2 7.0 12.8 4.8 12.0 1.8 12.8 1.9 14.4 10.6 2.2 9.3 5.6 6.3 14.6 21.5 10.1 5.6 5.2 5.8 12.2 11.0 6.8 13.4 3.5 4.9 10.5 4.0 1.1 8.6 3.5 13.2 9.7 10.4 1.9 6.0 11.9 12.4 11.9 6.3 8.7 13.5 3.8 3.7 11.7 11.7 8.1 20.5 15.0 15.9 16.5 16.0 11.6 17.7 3.3 5.3 5.8 9.6 14.9 9.1 12.3 8.0 21.1 11.1 16.6 10.7 21.4 10.6 18.6 2.5 10.0 11.5 13.8 10.1 0.0 17.0 18.5 20.5 9.8 0.0 10.3 6.1 9.1 35.2 11.3 11.4 25.0 22.5 16.9 18.5 10.4 6.1 28.5 0.0 11.8 20.7 11.4 9.2 4.5 0.8 11.5 8.8 9.8 16.2 13.7 6.8 15.5 21.5 16.4 28.6 11.1 13.1 9.3 8.9 16.8 7.0 1.8 1.1 0.9 0.8 1.2 0.3 1.3 1.2 1.3 2.5 0.6 1.2 2.2 0.0 1.1 0.6 1.2 2.1 0.3 5.4 6.6 6.2 7.0 5.6 6.3 5.2 5.8 4.9 6.0 6.3 8.1 0.6 0.0 0.0 4.2 4.0 0.4 0.1 0.4 12.5 0.7 1.1 0.8 0.0 1.5 0.1 0.0 2.1 0.4 0.5 0.4 1.9 0.6 0.1 1.1 1.0 1.8 0.0 4.2 4.6 0.6 0.4 1.4 9.7 1.0 7.0 0.8 0.7 1.1 0.3 0.0 3.3 0.0 0.0 1.2 1.2 0.0 0.9 1.5 1.8 1.9 0.3 0.5 0.0 3.5 2.8 0.0 1.2 0.7 9.2 0.1 0.1 0.9 0.8 0.3 0.0 0.4 1.9 1.4 0.4 13.8 1.0 0.3 3.5 0.4 0.6 0.1 H1-4 "H1.4, H1e, H1F4, H1s-4, HIST1H1E" ENSG00000168298 "H1.4 linker histone, cluster member" P10412 6 26156329-26157115 "Disease related genes, Predicted intracellular proteins" DNA-binding "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "bone marrow: 52.3;brain: 53.8" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 11.2;Cytotrophoblasts: 8.0;dendritic cells: 18.6;Extravillous trophoblasts: 11.3;Hofbauer cells: 7.7;Plasma cells: 6.7;Syncytiotrophoblasts: 7.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 53.8" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 10.5;U-266/70: 12.5;U-266/84: 15.1;U-87 MG: 12.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011506, HPA055907" Supported Supported "Nuclear speckles" NA Yes 8300000 "Cluster 6: Non-specific - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 16: U-266 - Nucleosome" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles" "CAB011506: AB_470256, HPA055907: AB_2682966" "unprognostic (6.96e-2)" "unprognostic (1.25e-1)" "unprognostic (3.06e-2)" "unprognostic (1.86e-1)" "unprognostic (9.62e-2)" "unprognostic (1.04e-2)" "unprognostic (5.78e-3)" "unprognostic (2.31e-2)" "unprognostic (1.24e-1)" "unprognostic (1.00e-1)" "unprognostic (1.20e-1)" "unprognostic (1.37e-1)" "unprognostic (7.72e-13)" "unprognostic (4.54e-3)" "unprognostic (3.46e-2)" "unprognostic (1.30e-3)" "unprognostic (2.18e-2)" 1.7 0.3 0.4 0.3 2.4 52.3 2.7 53.8 26.5 3.2 7.3 1.7 0.3 0.5 0.3 1.2 0.7 0.4 0.6 2.8 11.7 2.1 1.1 1.2 2.5 11.8 0.0 1.8 1.8 0.3 1.9 0.9 3.2 2.5 0.4 0.0 3.0 0.2 0.4 4.1 2.7 0.1 5.0 1.4 1.4 1.4 5.5 2.7 0.9 0.1 0.5 0.9 2.8 11.4 2.6 0.3 0.5 5.5 0.1 0.0 6.6 0.0 0.4 1.2 0.9 0.1 1.6 1.3 0.7 0.1 0.5 1.2 0.3 0.7 0.5 1.8 1.6 0.9 0.5 0.4 0.1 0.8 1.1 0.1 0.3 0.3 0.6 0.1 0.5 1.4 4.4 7.0 0.2 0.5 8.6 7.8 2.0 0.8 0.8 4.0 1.3 10.5 0.3 0.0 4.0 0.9 3.3 0.8 1.2 0.6 1.1 2.8 0.5 2.5 3.8 1.5 2.6 12.5 15.1 6.1 12.6 2.3 1.2 257.4 43.0 106.3 66.4 42.1 76.6 73.6 52.1 61.6 49.0 119.6 39.4 37.1 60.4 70.7 39.5 48.6 56.9 31.4 0.4 2.4 53.8 26.5 2.8 11.7 11.8 0.0 3.2 5.0 5.5 11.4 3.6 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.2 0.0 0.0 0.0 0.0 8.0 18.6 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 11.3 2.5 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 7.3 1.8 0.0 0.0 0.0 H2AX H2AFX ENSG00000188486 "H2A.X variant histone" P16104 11 119093854-119095467 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair, Host-virus interaction, Meiosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 43.7;Cytotrophoblasts: 83.2;dendritic cells: 34.0;Extravillous trophoblasts: 106.6;Hofbauer cells: 45.8;Syncytiotrophoblasts: 64.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012264, HPA041189, HPA051647" Supported Supported "Nucleoplasm,Nuclear speckles" Yes Yes "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Nuclear speckles" "CAB012264: AB_297215, HPA041189: AB_2677357, HPA051647: AB_2681563" "unprognostic (1.44e-1)" "unprognostic (1.96e-1)" "unprognostic (6.46e-2)" "unprognostic (6.41e-2)" "unprognostic (3.07e-1)" "unprognostic (3.25e-1)" "prognostic unfavorable (1.51e-4)" "unprognostic (2.32e-3)" "unprognostic (1.93e-1)" "unprognostic (3.07e-3)" "unprognostic (6.78e-2)" "unprognostic (9.31e-2)" "prognostic unfavorable (5.47e-9)" "unprognostic (1.21e-3)" "unprognostic (1.20e-1)" "unprognostic (1.20e-1)" "unprognostic (1.99e-2)" 13.2 20.7 35.2 12.6 37.8 24.9 8.0 39.0 42.2 13.3 20.6 18.6 13.3 14.0 2.1 43.6 13.1 3.1 13.4 33.7 32.3 17.0 13.9 14.3 16.0 43.9 38.9 18.7 11.6 3.4 24.3 11.0 37.8 15.7 4.3 6.6 11.4 4.7 12.4 18.1 18.8 3.5 38.0 24.0 16.1 15.4 37.8 30.5 10.4 3.6 12.0 11.8 15.7 51.8 132.1 77.9 120.3 72.3 10.9 7.9 126.4 146.0 44.0 80.3 70.4 124.0 55.1 89.7 85.9 34.0 60.5 134.0 57.5 41.7 21.5 133.4 161.0 182.2 20.7 129.8 11.4 90.5 108.9 6.7 9.0 34.2 21.0 13.1 40.7 115.4 149.9 143.1 38.9 335.6 207.8 269.9 87.5 60.0 162.6 200.7 141.6 42.7 37.5 56.3 127.6 152.0 116.0 66.6 20.6 20.6 99.8 68.2 50.9 77.7 204.2 63.8 110.2 38.7 40.8 92.3 17.9 145.2 155.0 3.8 1.3 4.2 1.6 0.6 0.8 0.9 1.7 1.7 1.8 0.8 1.1 1.0 0.6 2.2 0.8 0.8 1.6 1.2 35.2 37.8 39.0 42.2 33.7 32.3 43.9 38.9 37.8 38.0 37.8 51.8 43.7 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 0.0 0.0 0.0 83.2 34.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 106.6 9.4 0.0 0.0 0.0 0.0 0.0 0.0 45.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 64.2 7.2 0.0 0.0 0.0 HDAC4 "BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACA, KIAA0288" ENSG00000068024 "Histone deacetylase 4" P56524 2 239048168-239401654 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "Autism spectrum disorder, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 58.2" "Group enriched" "Detected in many" 4 "Astrocytes: 62.0;Early spermatids: 69.9;Excitatory neurons: 118.1;Inhibitory neurons: 84.9;Late spermatids: 59.0;Microglial cells: 38.4;Oligodendrocyte precursor cells: 85.5;Oligodendrocytes: 124.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 32.0;neutrophil: 47.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 47.7" "Cell line enhanced" "Detected in many" "JURKAT: 49.1;MOLT-4: 48.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048723, HPA071448" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear speckles" "Nucleoplasm, Cytosol" "HPA048723: AB_2680501, HPA071448: " "unprognostic (1.54e-1)" "unprognostic (1.76e-2)" "unprognostic (1.33e-1)" "unprognostic (1.18e-3)" "unprognostic (2.43e-2)" "unprognostic (2.39e-3)" "unprognostic (3.06e-4)" "unprognostic (1.00e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (6.33e-4)" "prognostic favorable (1.13e-4)" "unprognostic (1.40e-1)" "unprognostic (4.82e-3)" "unprognostic (2.40e-1)" "unprognostic (3.26e-2)" "unprognostic (1.32e-2)" "unprognostic (6.04e-2)" 4.4 6.3 9.3 5.0 12.0 17.0 3.8 0.6 13.4 7.5 0.1 29.0 2.7 9.1 2.5 8.0 6.7 7.1 5.2 9.0 6.5 3.7 2.4 3.9 3.5 9.9 6.1 7.5 3.7 2.7 6.5 1.5 11.2 5.6 3.4 2.4 3.3 5.9 58.2 5.9 7.2 6.2 2.3 5.6 7.2 9.2 6.7 9.7 4.2 35.6 2.5 10.0 4.5 10.1 3.2 5.8 4.1 6.1 4.5 3.9 5.9 3.0 2.3 2.3 1.7 2.9 7.5 2.0 1.9 3.4 3.6 3.4 4.0 2.0 1.4 12.8 1.8 3.1 5.1 5.8 3.8 5.5 4.6 4.4 2.6 4.6 3.3 2.3 2.4 49.1 3.7 4.5 2.7 4.7 48.1 10.7 4.0 6.0 2.8 7.6 7.2 4.0 5.3 4.4 4.6 6.4 5.3 2.5 16.2 2.6 1.0 17.9 1.9 5.0 0.4 6.8 4.6 3.3 3.2 3.1 6.9 6.9 7.4 32.0 10.2 2.3 1.0 3.3 1.2 0.2 1.1 1.0 1.0 0.1 0.5 0.5 47.7 3.2 1.7 0.6 1.7 1.1 9.3 12.0 0.6 13.4 9.0 6.5 9.9 6.1 11.2 2.3 6.7 10.1 8.6 3.2 7.4 62.0 5.2 7.9 2.9 3.0 8.6 12.2 6.2 4.8 13.3 7.2 2.9 11.0 2.1 1.5 12.8 4.1 0.0 2.8 69.9 7.0 15.1 7.1 6.0 6.1 118.1 2.2 1.7 14.0 7.7 7.4 2.5 6.6 11.7 6.7 3.2 16.8 84.9 5.2 2.0 17.2 10.0 59.0 11.8 10.3 5.4 38.4 14.9 8.6 15.5 85.5 124.0 1.9 1.6 12.4 7.0 6.4 5.0 1.6 2.6 7.1 0.0 18.7 6.5 2.8 3.3 11.1 9.7 1.4 12.2 4.9 6.4 2.7 HDAC5 "FLJ90614, KIAA0600, NY-CO-9" ENSG00000108840 "Histone deacetylase 5" Q9UQL6 17 44076746-44123702 "Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 118.9;Syncytiotrophoblasts: 218.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019400, HPA030991" Approved Supported "Nuclear speckles,Golgi apparatus,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nuclear speckles" "Golgi apparatus, Cytosol" "CAB019400: AB_2116626, HPA030991: AB_10795286" "unprognostic (1.30e-2)" "prognostic favorable (6.14e-4)" "unprognostic (6.65e-2)" "unprognostic (8.06e-2)" "unprognostic (3.49e-1)" "unprognostic (3.52e-2)" "prognostic unfavorable (3.12e-5)" "unprognostic (8.80e-3)" "unprognostic (3.80e-2)" "unprognostic (2.37e-2)" "unprognostic (4.91e-3)" "unprognostic (4.30e-1)" "prognostic favorable (3.30e-5)" "unprognostic (1.51e-2)" "unprognostic (3.11e-1)" "unprognostic (6.00e-2)" "unprognostic (1.76e-2)" 30.8 24.7 39.3 10.9 33.5 20.7 28.8 48.8 48.5 40.6 3.3 36.3 11.6 33.2 15.5 45.1 34.1 15.9 53.5 40.4 31.6 24.8 17.4 33.6 14.0 37.6 41.1 45.0 22.5 31.5 48.1 22.6 35.1 29.2 7.3 24.3 22.9 15.1 77.5 71.3 22.9 14.8 22.4 26.4 24.0 19.7 40.0 10.4 30.8 28.6 11.6 29.2 37.0 50.3 8.7 5.5 14.9 3.5 28.2 21.7 53.6 22.8 56.1 11.3 18.1 12.3 9.1 13.5 9.0 54.4 16.5 6.9 17.6 9.8 4.7 21.2 28.7 26.3 18.6 28.6 12.2 8.7 35.7 31.2 16.5 12.8 15.8 19.0 9.3 10.6 20.0 26.5 65.5 6.7 14.3 26.2 16.4 6.7 13.0 54.7 41.6 35.4 1.2 3.8 38.6 20.3 6.7 27.6 31.2 21.8 39.3 49.6 5.1 27.8 17.5 6.6 11.7 43.6 39.7 16.2 16.0 10.7 13.4 11.6 9.2 9.7 5.4 13.5 3.8 7.2 4.3 5.4 11.1 7.5 4.5 4.0 20.9 4.5 16.8 9.7 4.1 7.3 39.3 33.5 48.8 48.5 40.4 31.6 37.6 41.1 35.1 22.4 40.0 50.3 24.0 12.8 13.7 11.1 20.4 29.2 32.3 9.0 26.2 87.8 23.8 21.3 27.1 30.0 11.9 20.2 118.9 21.9 19.6 22.4 21.5 17.2 20.2 17.1 10.7 22.1 46.0 9.3 18.9 8.7 53.1 24.1 10.2 25.1 12.6 47.0 24.3 9.3 22.7 82.4 31.0 14.9 6.1 18.5 17.8 10.0 48.4 29.8 14.2 12.2 16.5 18.9 11.3 14.1 26.2 11.5 16.5 43.6 14.2 41.2 21.5 7.3 12.4 60.4 65.7 31.8 40.1 4.2 32.7 28.1 32.8 218.1 17.0 29.9 11.3 25.3 HEXIM2 FLJ32384 ENSG00000168517 "HEXIM P-TEFb complex subunit 2" Q96MH2 17 45160700-45170040 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 56.9;testis: 44.6" "Group enriched" "Detected in many" 5 "Early spermatids: 150.9;Late spermatids: 274.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 55.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023323, HPA028455" Enhanced Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 37: B-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Nuclear speckles" "HPA023323: AB_1850651, HPA028455: AB_10602603" "unprognostic (9.03e-3)" "unprognostic (2.18e-2)" "unprognostic (4.01e-2)" "prognostic favorable (2.53e-4)" "unprognostic (2.36e-1)" "unprognostic (6.35e-3)" "unprognostic (9.70e-2)" "unprognostic (1.34e-2)" "unprognostic (1.03e-1)" "prognostic favorable (9.85e-4)" "unprognostic (2.34e-3)" "unprognostic (1.93e-1)" "unprognostic (1.29e-2)" "unprognostic (2.32e-3)" "unprognostic (6.98e-2)" "unprognostic (2.04e-1)" "unprognostic (1.90e-2)" 4.8 10.1 8.5 5.2 9.0 4.6 4.6 12.2 9.8 4.9 13.4 7.1 10.2 4.7 4.5 4.7 5.6 7.8 6.9 7.2 7.3 10.5 15.1 4.2 7.3 9.1 8.4 6.2 10.8 7.5 7.9 3.4 8.2 6.0 2.7 4.8 11.5 5.7 56.9 6.6 7.6 2.8 8.6 6.4 8.1 44.6 9.0 5.0 8.7 15.1 3.3 5.8 3.9 9.1 9.0 31.7 6.9 15.3 7.5 12.3 13.1 4.9 5.9 7.8 8.6 12.1 23.4 5.6 25.0 3.5 4.0 14.6 6.8 6.0 2.4 12.9 10.9 4.2 33.4 55.1 5.4 3.6 8.9 10.7 5.6 6.8 2.4 15.1 3.9 11.3 4.6 13.4 3.6 15.6 5.7 7.6 7.5 12.5 13.8 7.7 10.4 17.1 9.8 8.8 8.2 7.2 4.4 8.8 20.7 4.8 23.3 6.1 3.8 14.0 7.5 9.4 11.7 20.7 23.9 5.2 11.0 6.6 10.7 8.2 11.7 10.6 4.8 9.4 8.0 10.1 3.5 5.8 10.2 5.5 2.7 5.0 8.2 8.1 3.1 12.9 4.7 12.0 8.5 9.0 12.2 9.8 7.2 7.3 9.1 8.4 8.2 8.6 9.0 9.1 3.1 0.0 1.5 1.6 4.8 2.0 4.0 3.1 5.7 13.1 6.8 7.2 0.3 5.7 2.5 1.8 4.2 11.7 4.1 2.7 19.6 5.5 150.9 4.9 3.0 4.3 4.8 0.8 2.2 1.6 5.4 3.9 3.6 3.4 7.0 8.8 5.3 7.7 7.0 3.3 3.0 6.2 4.1 9.3 3.3 274.9 5.9 16.4 3.6 1.0 4.9 11.6 5.2 1.5 3.1 1.6 3.1 7.2 7.2 2.0 18.3 36.2 1.8 9.9 0.0 5.4 4.6 41.4 13.7 3.3 3.0 6.2 2.1 7.2 6.1 2.5 HOXA6 "HOX1, HOX1B" ENSG00000106006 "Homeobox A6" P31267 7 27145396-27150603 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 10.0" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 5.2;Distal enterocytes: 7.5;Distal tubular cells: 5.9;Endometrial stromal cells: 14.8;Enteroendocrine cells: 9.0;Smooth muscle cells: 6.2;Undifferentiated cells: 8.0" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 7.7" "Immune cell enhanced" "Detected in single" "basophil: 3.1" "Lineage enhanced" "Detected in single" "granulocytes: 3.1" "Group enriched" "Detected in many" 9 "AN3-CA: 61.7;HEK 293: 84.4" "Region enriched" "Detected in single" 34 "pons and medulla: 3.3" "HPA004203, HPA077900" Approved Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 36: Stromal cells - Cell proliferation" Nucleoplasm "Nuclear speckles" "HPA004203: AB_1079079, HPA077900: " "unprognostic (1.70e-1)" "unprognostic (6.76e-3)" "unprognostic (2.70e-2)" "prognostic unfavorable (1.40e-4)" "unprognostic (1.06e-1)" "unprognostic (6.06e-2)" "unprognostic (9.73e-2)" "unprognostic (6.32e-2)" "unprognostic (2.94e-2)" "unprognostic (7.82e-2)" "unprognostic (2.17e-1)" "prognostic favorable (2.03e-4)" "unprognostic (1.45e-1)" "unprognostic (2.81e-2)" "unprognostic (3.93e-1)" 3.0 2.7 0.1 1.4 0.1 0.2 2.4 0.0 0.2 2.5 0.0 6.6 0.2 5.4 3.7 0.3 10.0 0.2 0.0 0.1 0.0 4.5 0.0 2.1 1.1 7.1 0.0 0.2 0.0 0.3 0.0 0.1 1.8 2.5 1.5 0.0 0.1 1.9 1.2 2.9 4.2 1.4 7.7 0.2 1.3 0.0 0.0 0.1 0.2 0.0 0.0 3.0 1.4 5.4 1.2 2.1 0.1 61.7 0.1 0.0 0.2 0.5 0.6 0.4 0.6 1.5 7.2 1.5 2.3 0.5 0.2 2.8 1.5 0.0 0.0 1.9 84.4 1.0 1.2 0.8 0.0 1.3 2.1 4.9 0.1 0.0 0.8 0.1 2.9 2.0 0.4 0.0 0.7 0.8 0.1 0.3 0.1 0.4 2.1 8.4 0.0 0.0 5.9 3.9 6.4 0.0 2.9 0.3 1.3 0.0 0.8 0.8 0.0 0.1 0.9 3.3 2.3 0.0 0.0 1.4 0.0 6.2 6.1 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 7.1 0.0 1.8 7.7 0.0 5.4 2.1 0.0 0.0 0.0 0.3 0.3 1.6 0.0 0.0 0.0 4.0 5.2 0.0 0.0 0.0 1.8 0.0 0.0 0.5 7.5 5.9 0.0 0.0 0.6 14.8 1.9 9.0 0.0 0.0 0.0 0.0 1.8 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.7 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 3.9 0.0 0.0 1.0 3.4 1.3 0.1 0.0 0.0 3.7 6.2 0.0 0.0 0.3 0.4 0.0 0.4 0.1 8.0 1.4 HP1BP3 HP1-BP74 ENSG00000127483 "Heterochromatin protein 1 binding protein 3" Q5SSJ5 1 20740266-20787323 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028215, HPA054295" Supported Supported "Nuclear speckles" NA Yes 30000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nuclear speckles" "HPA028215: AB_10601021, HPA054295: AB_2682440" "unprognostic (3.90e-3)" "unprognostic (6.83e-2)" "unprognostic (7.69e-2)" "unprognostic (3.66e-2)" "unprognostic (1.31e-1)" "unprognostic (1.25e-3)" "prognostic unfavorable (2.76e-4)" "unprognostic (1.97e-1)" "unprognostic (3.26e-2)" "unprognostic (1.68e-1)" "unprognostic (1.94e-2)" "unprognostic (9.50e-2)" "unprognostic (6.86e-2)" "unprognostic (1.65e-1)" "unprognostic (6.30e-2)" "unprognostic (1.27e-1)" "unprognostic (2.43e-2)" 87.9 78.9 62.2 76.2 75.1 141.7 80.1 69.6 76.5 143.6 62.1 107.9 71.3 116.5 63.0 94.8 96.7 75.3 75.7 64.5 66.6 83.5 66.5 84.1 91.4 68.1 64.4 135.6 74.4 98.1 60.9 85.9 67.5 81.3 88.2 96.4 83.0 74.3 113.9 86.9 93.8 100.3 61.3 89.2 83.1 54.5 68.7 134.5 106.3 78.7 90.3 93.9 114.2 107.6 207.3 106.1 261.6 157.5 152.3 172.8 157.3 230.2 182.4 156.7 163.1 97.6 232.0 208.2 113.4 176.6 108.4 171.9 136.7 125.5 199.8 306.5 124.7 296.2 230.5 85.4 98.1 209.7 181.7 135.1 90.6 159.0 208.5 193.0 160.5 245.1 169.9 251.8 180.1 64.2 323.5 93.0 69.3 152.6 126.3 250.4 255.0 219.2 113.6 66.6 175.0 180.0 279.8 112.9 181.2 132.9 117.3 138.7 196.4 176.2 164.2 180.7 139.2 144.0 194.2 246.7 150.2 213.0 204.0 102.4 55.3 202.6 57.1 45.0 59.7 70.8 61.9 62.1 52.2 58.4 80.4 54.5 66.1 63.3 54.9 59.5 71.6 49.0 62.2 75.1 69.6 76.5 64.5 66.6 68.1 64.4 67.5 61.3 68.7 107.6 129.4 150.6 156.2 96.9 112.1 130.4 137.4 81.6 159.9 117.8 116.6 108.7 161.4 94.4 94.5 104.8 54.2 87.6 144.7 105.6 154.6 87.0 40.8 85.3 184.6 136.8 103.7 214.6 98.3 93.4 70.7 161.9 98.8 128.2 137.8 131.8 129.2 101.0 72.6 80.8 93.7 113.4 83.4 100.7 104.1 22.3 172.7 116.9 113.8 130.2 111.2 119.5 127.7 142.7 189.9 113.0 90.1 162.5 162.0 124.6 91.7 110.7 54.6 97.6 157.8 145.2 148.3 141.3 110.1 201.8 134.5 92.9 151.9 116.2 115.3 118.4 HSF4 CTM ENSG00000102878 "Heat shock transcription factor 4" Q9ULV5 16 67164681-67169945 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Stress response, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 69.2" "Cell type enhanced" "Detected in many" "Astrocytes: 38.5;Excitatory neurons: 30.9;Horizontal cells: 43.7;Inhibitory neurons: 30.0;Leydig cells: 32.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 17.1;T-47d: 12.9;U-266/70: 22.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048584 Supported "Nuclear speckles" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 62: Horizontal cells - Visual perception" "Nuclear speckles" "HPA048584: AB_2680452" "unprognostic (1.90e-1)" "unprognostic (3.05e-2)" "prognostic unfavorable (8.24e-5)" "unprognostic (9.20e-3)" "unprognostic (2.61e-1)" "unprognostic (1.43e-1)" "unprognostic (8.98e-2)" "unprognostic (1.36e-1)" "unprognostic (4.06e-2)" "unprognostic (2.45e-1)" "unprognostic (2.85e-2)" "unprognostic (4.26e-3)" "prognostic unfavorable (2.19e-6)" "unprognostic (1.20e-1)" "unprognostic (1.33e-1)" "unprognostic (4.48e-2)" "unprognostic (8.74e-3)" 12.4 23.7 43.6 1.3 44.3 1.8 12.7 44.6 69.2 17.9 39.2 10.1 4.8 12.4 4.8 11.0 21.1 3.6 20.0 44.6 43.7 17.1 20.3 8.7 1.6 45.0 41.9 19.8 35.9 4.3 30.1 3.3 46.4 28.3 1.8 5.6 19.0 1.9 25.9 14.5 6.1 2.1 41.3 6.0 14.4 7.0 43.3 1.1 17.9 4.1 1.1 18.8 10.9 45.8 1.6 1.1 0.0 1.1 0.5 3.0 5.2 0.5 0.6 0.2 0.0 2.4 3.5 0.1 2.5 1.1 0.7 5.9 0.4 0.7 0.2 2.3 2.2 0.6 4.5 3.1 2.3 0.3 4.4 1.3 4.8 0.2 2.5 17.1 0.9 4.0 1.5 5.1 2.3 1.5 0.8 1.8 0.1 3.4 3.2 2.0 1.7 8.7 4.4 2.5 3.5 7.6 4.9 3.0 7.8 2.1 12.9 4.5 0.9 1.6 1.6 6.4 1.5 22.3 3.7 1.5 4.9 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.6 44.3 44.6 69.2 44.6 43.7 45.0 41.9 46.4 41.3 43.3 45.8 2.6 3.2 7.7 38.5 1.1 3.1 3.4 2.9 4.6 10.8 9.1 7.7 5.3 4.3 2.7 3.7 2.1 1.0 0.7 2.9 0.0 1.0 0.5 4.1 2.8 1.6 1.2 0.0 30.9 1.3 0.6 6.0 14.8 7.0 1.3 2.3 2.9 5.7 21.9 43.7 30.0 3.0 2.0 0.8 2.5 1.8 32.9 4.6 10.6 5.6 1.5 8.8 0.0 4.0 15.2 1.4 3.5 22.2 1.5 4.0 0.4 2.4 4.8 11.4 0.0 5.4 3.2 0.4 2.3 3.6 3.4 0.7 0.9 1.9 2.9 2.0 HSPB3 HSPL27 ENSG00000169271 "Heat shock protein family B (small) member 3" Q12988 5 54455699-54456377 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Stress response" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 17 "heart muscle: 406.9;skeletal muscle: 217.2;tongue: 218.9" "Cell type enriched" "Detected in some" 18 "Cardiomyocytes: 398.1" "Cancer enriched" "Detected in many" 6 "head and neck cancer: 7.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 86.3;fHDF/TERT166: 39.1;HSkMC: 16.3;LHCN-M2: 12.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA062124 Supported "Nuclear speckles" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nuclear speckles" "HPA062124: AB_2684690" "unprognostic (1.44e-1)" "unprognostic (2.21e-1)" "unprognostic (1.78e-3)" "unprognostic (3.06e-1)" "unprognostic (2.25e-3)" "unprognostic (1.13e-1)" "unprognostic (4.41e-3)" "unprognostic (6.42e-2)" "unprognostic (1.85e-1)" "unprognostic (2.70e-2)" "unprognostic (2.73e-1)" "unprognostic (2.82e-2)" "unprognostic (7.15e-2)" 1.4 0.2 4.6 0.1 5.6 0.2 2.1 4.0 7.5 0.9 4.1 5.2 0.2 7.5 0.4 16.5 3.0 0.2 406.9 6.3 7.2 0.4 0.1 2.8 0.0 4.1 4.0 1.0 0.1 0.0 3.6 0.1 4.4 8.6 2.1 1.6 6.7 0.8 217.2 2.2 0.9 10.4 4.1 0.7 0.9 1.8 4.1 0.7 0.3 218.9 0.0 3.7 0.8 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 86.3 0.1 0.1 0.4 0.0 0.0 0.3 39.1 0.1 4.8 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.4 0.0 0.0 16.3 5.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 4.4 0.1 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.6 5.6 4.0 7.5 6.3 7.2 4.1 4.0 4.4 4.1 4.1 6.4 0.0 0.0 0.0 0.3 0.0 6.4 0.4 3.2 0.0 0.1 0.0 0.0 398.1 0.0 0.3 0.0 0.0 0.1 0.0 10.5 0.0 0.0 0.1 0.7 0.2 3.5 0.0 0.0 4.3 0.0 0.0 14.4 0.0 1.3 0.0 0.1 0.0 0.0 0.1 1.7 6.5 0.0 0.0 0.0 4.9 0.4 0.6 0.2 3.6 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.5 6.6 21.3 7.2 0.4 0.0 0.0 5.3 0.1 0.2 0.1 0.3 0.3 IL15 "IL-15, MGC9721" ENSG00000164136 "Interleukin 15" P40933 4 141636583-141733987 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 78.0;monocytes: 72.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 17.6;Karpas-707: 18.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB004457, HPA037738" Approved Supported "Nucleoplasm,Nuclear speckles" "Secreted to blood" NA NA 182000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 20: HeLa - Mitochondria" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoplasm, Nuclear speckles" "CAB004457: AB_2124575, HPA037738: AB_2675640" "unprognostic (1.10e-2)" "unprognostic (1.53e-1)" "unprognostic (1.04e-2)" "unprognostic (8.57e-2)" "unprognostic (8.77e-3)" "unprognostic (1.69e-1)" "unprognostic (1.17e-1)" "unprognostic (2.90e-1)" "unprognostic (1.80e-1)" "unprognostic (1.48e-1)" "unprognostic (5.20e-2)" "unprognostic (1.74e-2)" "unprognostic (3.75e-2)" "unprognostic (1.09e-1)" "unprognostic (4.03e-2)" "unprognostic (3.29e-2)" "unprognostic (1.54e-1)" 7.7 3.4 1.3 7.1 1.4 4.0 6.0 2.1 1.8 5.3 1.4 7.7 6.1 4.5 2.5 4.4 4.5 4.9 5.1 1.2 1.3 7.9 3.6 7.8 9.7 2.3 1.3 1.5 2.7 0.7 3.6 3.1 1.8 4.1 5.3 4.3 3.6 2.7 8.6 3.4 10.0 4.6 1.5 15.4 4.8 2.5 1.8 6.8 15.6 3.4 6.6 4.5 6.4 1.9 2.8 6.3 0.3 0.6 0.9 5.4 1.6 6.7 6.1 6.8 5.5 3.4 8.1 2.5 8.5 6.2 6.0 4.4 0.1 3.4 3.6 17.6 1.7 0.5 16.7 0.5 4.5 1.9 1.3 2.1 1.5 4.4 0.5 13.7 4.3 2.3 4.0 18.8 4.2 0.9 4.2 0.3 3.3 2.3 1.7 1.0 16.0 0.5 9.2 0.8 0.6 1.6 3.1 4.7 3.2 0.8 0.9 0.3 6.6 6.9 4.3 2.0 4.2 13.0 1.8 1.0 7.2 0.8 2.5 10.4 16.1 0.6 2.7 15.1 5.0 4.1 3.3 2.5 5.5 4.0 1.4 1.4 1.2 3.2 16.5 0.2 2.0 6.1 1.3 1.4 2.1 1.8 1.2 1.3 2.3 1.3 1.8 1.5 1.8 1.9 14.8 0.0 2.8 0.3 9.9 6.1 2.5 2.1 2.2 0.6 2.1 1.3 2.9 2.8 5.3 5.5 0.0 1.2 5.0 4.7 0.0 9.4 6.6 6.9 78.0 14.8 0.0 1.3 2.0 14.0 1.6 5.5 4.1 5.9 0.0 0.9 11.4 2.5 4.7 0.0 4.8 5.4 0.0 17.0 22.1 2.5 2.8 16.7 8.8 4.7 72.0 21.1 8.2 3.0 0.2 19.8 8.2 1.2 9.3 6.2 9.9 12.0 3.9 0.9 6.6 7.6 4.0 1.2 0.8 5.6 3.4 0.3 6.0 0.1 2.6 3.0 IL16 "FLJ16806, FLJ42735, HsT19289, IL-16, LCF, prIL-16" ENSG00000172349 "Interleukin 16" Q14005 15 81159575-81314058 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Chemotaxis, Host-virus interaction, Transcription, Transcription regulation" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 135.3" "Cell type enhanced" "Detected in many" "B-cells: 135.3;dendritic cells: 78.1;Kupffer cells: 59.2;Langerhans cells: 94.4;NK-cells: 121.5;Plasma cells: 55.6;T-cells: 76.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 57.3" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 27.7;HEL: 29.4;HMC-1: 50.6;RPMI-8226: 51.0;U-266/70: 60.3;U-698: 25.8;U-937: 35.1" "Group enriched" "Detected in all" 11 "cerebellum: 54.5;hippocampal formation: 27.0" "Region enriched" "Detected in many" 12 "cerebellum: 48.8" "CAB005247, HPA018467, HPA048861" Enhanced Supported "Nuclear speckles,Plasma membrane,Cytosol" "Secreted to blood" NA NA 208000 7300 "Cluster 5: Granulocytes - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear speckles" "Plasma membrane, Cytosol" "CAB005247: AB_2124730, HPA018467: AB_1851642, HPA048861: " "unprognostic (8.23e-3)" "unprognostic (2.70e-3)" "unprognostic (1.97e-2)" "unprognostic (9.61e-4)" "unprognostic (2.01e-1)" "unprognostic (5.26e-4)" "unprognostic (2.63e-2)" "unprognostic (6.72e-3)" "unprognostic (2.25e-1)" "unprognostic (3.91e-1)" "unprognostic (1.47e-1)" "unprognostic (6.21e-2)" "unprognostic (3.16e-3)" "unprognostic (1.21e-1)" "unprognostic (3.23e-2)" "unprognostic (5.26e-2)" "unprognostic (1.29e-1)" 18.9 6.3 3.5 63.3 3.0 62.1 15.5 57.3 4.1 9.6 13.8 14.4 11.3 9.9 7.7 7.4 17.8 16.2 5.9 2.9 5.7 3.2 9.7 23.7 132.6 5.9 5.7 6.1 2.6 2.3 2.1 9.0 10.5 5.8 16.8 0.5 11.2 4.5 3.3 12.0 39.9 9.8 5.8 86.2 15.6 4.2 5.2 130.4 6.9 8.5 135.3 18.9 10.4 7.6 0.0 0.0 0.0 0.1 17.5 7.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 27.7 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.4 0.0 29.4 0.0 0.0 0.9 21.0 50.6 0.9 0.0 0.1 0.6 0.0 0.4 3.5 3.2 10.7 0.1 0.0 1.7 22.2 0.0 0.1 0.0 0.1 0.1 51.0 0.0 0.2 0.1 0.1 0.1 0.0 9.9 0.0 0.0 4.6 0.2 0.3 0.2 1.0 0.0 60.3 5.5 25.8 1.8 35.1 1.5 252.8 116.2 321.3 164.5 142.7 185.9 166.0 170.6 180.6 150.9 157.2 224.9 185.6 282.5 213.2 149.1 113.7 197.0 338.0 3.5 3.0 57.3 4.1 2.9 5.7 5.9 5.7 10.5 5.8 5.2 7.6 9.4 3.2 6.6 0.0 135.3 8.2 0.2 0.8 1.2 0.2 0.8 1.4 2.7 8.6 1.9 1.8 0.0 0.3 78.1 0.3 0.0 0.1 1.4 3.1 6.6 7.5 0.0 20.2 3.4 0.2 0.3 15.9 1.1 0.7 27.1 0.0 26.7 9.2 19.0 0.0 4.9 0.3 0.0 59.2 94.4 1.4 10.8 33.1 28.4 18.7 30.2 0.3 121.5 0.0 0.3 0.0 1.2 18.0 55.6 0.1 0.1 0.4 7.7 0.7 6.6 1.1 3.2 2.1 7.5 1.2 3.7 0.4 76.3 0.2 0.7 0.2 ILRUN "C6orf106, dJ391O22.4, FLJ22195" ENSG00000196821 "Inflammation and lipid regulator with UBA-like and NBR1-like domains" Q9H6K1 6 34587288-34696859 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 211.7" "Cell type enhanced" "Detected in some" "Adipocytes: 9.9;Cardiomyocytes: 73.7;Cytotrophoblasts: 13.7;dendritic cells: 11.8;Hofbauer cells: 15.6;Syncytiotrophoblasts: 21.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034489, HPA034490" Approved Supported "Nuclear speckles,Centrosome,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles" "Centrosome, Cytosol" "HPA034489: AB_10669991, HPA034490: AB_2674186" "unprognostic (3.76e-2)" "unprognostic (2.51e-1)" "unprognostic (7.71e-2)" "unprognostic (1.02e-2)" "unprognostic (1.41e-1)" "unprognostic (1.32e-1)" "unprognostic (8.40e-2)" "unprognostic (9.94e-2)" "unprognostic (7.57e-2)" "unprognostic (5.68e-2)" "unprognostic (3.55e-2)" "unprognostic (1.31e-1)" "unprognostic (1.08e-2)" "unprognostic (1.04e-1)" "unprognostic (1.25e-1)" "unprognostic (1.05e-1)" "unprognostic (1.53e-1)" 57.0 35.3 38.4 31.4 39.3 28.6 35.2 48.8 51.6 26.6 36.2 43.4 30.1 29.5 29.0 42.1 27.2 29.3 76.8 39.8 39.8 43.1 77.1 42.5 34.0 41.6 49.9 25.8 30.3 47.3 24.5 30.4 41.5 30.7 29.8 46.7 33.9 32.4 211.7 37.0 35.7 39.4 39.6 31.6 35.0 67.8 43.7 32.9 37.4 187.4 44.8 40.2 28.1 41.4 94.0 41.8 40.3 59.8 95.7 51.9 48.5 63.5 72.3 72.1 89.4 83.0 42.1 107.0 46.1 62.3 99.5 90.7 120.0 52.6 90.3 151.4 47.0 89.2 47.3 80.0 93.4 76.0 96.2 35.4 108.0 73.3 66.4 49.5 58.6 43.9 103.0 43.6 41.7 56.3 52.7 52.7 37.7 152.0 37.3 40.6 52.2 57.0 57.0 91.2 48.6 38.0 93.3 44.9 91.8 82.1 56.5 63.3 60.1 59.1 45.6 63.0 62.7 63.2 154.3 81.8 21.3 66.7 70.1 23.9 3.7 8.1 8.9 6.6 4.7 6.7 6.4 7.1 4.4 8.1 3.5 5.5 4.6 6.2 8.3 2.2 10.0 5.7 38.4 39.3 48.8 51.6 39.8 39.8 41.6 49.9 41.5 39.6 43.7 41.4 9.9 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 73.7 0.0 0.0 0.0 0.0 13.7 11.8 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 8.6 7.0 0.0 0.0 0.0 0.0 0.0 0.0 15.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 21.6 1.6 0.0 0.0 0.0 ITPKC "IP3-3KC, IP3KC" ENSG00000086544 "Inositol-trisphosphate 3-kinase C" Q96DU7 19 40717112-40740860 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 96.7" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 151.4;Glandular and luminal cells: 139.3;Squamous epithelial cells: 160.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTCEpi: 46.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050760, HPA053003" Approved Supported "Nuclear speckles" No No "Cluster 10: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" "Nuclear speckles" "HPA050760: AB_2681227, HPA053003: AB_2682011" "unprognostic (4.27e-2)" "unprognostic (3.73e-2)" "unprognostic (8.31e-2)" "unprognostic (9.12e-3)" "unprognostic (1.10e-2)" "unprognostic (9.81e-2)" "unprognostic (6.06e-2)" "prognostic unfavorable (4.91e-4)" "unprognostic (1.48e-1)" "unprognostic (1.54e-3)" "unprognostic (1.84e-3)" "unprognostic (2.63e-1)" "unprognostic (2.59e-1)" "unprognostic (1.70e-1)" "unprognostic (2.86e-2)" "unprognostic (3.45e-2)" "unprognostic (3.32e-1)" 45.3 13.9 11.2 10.8 9.6 3.5 29.4 9.4 10.7 32.6 11.6 16.8 11.7 18.6 4.7 96.7 25.0 23.0 19.3 10.0 10.7 18.8 17.7 41.8 6.0 15.0 11.5 12.9 22.8 10.3 22.0 10.3 11.6 27.1 6.8 5.5 31.1 10.5 18.4 51.0 16.9 16.3 10.8 14.5 26.3 6.0 15.2 8.7 17.2 8.9 13.9 22.4 42.0 9.3 12.9 12.0 7.3 11.5 32.2 27.8 11.6 7.5 15.7 7.6 6.7 17.3 13.1 3.5 8.5 9.7 5.7 13.3 7.3 32.6 3.1 6.7 7.5 2.7 4.5 12.3 31.8 3.0 3.6 38.8 46.4 7.2 26.5 10.3 18.9 5.0 10.6 6.1 7.5 15.7 4.4 4.5 3.7 29.4 5.4 4.7 3.6 4.9 12.0 21.5 5.2 6.5 7.6 30.5 7.2 8.4 14.1 7.6 12.2 4.9 7.3 3.3 5.1 3.5 0.9 3.7 7.6 3.1 5.4 0.9 0.7 0.4 0.8 0.3 0.3 0.3 0.6 0.4 0.3 0.7 0.4 0.5 0.3 0.2 0.5 0.5 0.6 0.4 11.2 9.6 9.4 10.7 10.0 10.7 15.0 11.5 11.6 10.8 15.2 9.3 75.4 86.6 35.2 6.5 2.7 60.4 72.4 17.4 39.9 10.0 88.4 44.4 4.1 7.2 29.7 3.7 0.0 7.7 2.8 57.7 1.9 13.9 2.1 67.5 23.2 26.4 16.7 3.2 7.4 12.3 5.5 20.1 151.4 139.3 3.8 4.3 25.7 6.8 2.9 5.0 6.0 27.2 2.0 7.8 9.6 2.2 11.8 6.8 19.6 6.5 3.1 3.7 3.1 9.0 3.5 23.2 50.8 7.5 1.2 65.3 28.7 4.4 29.4 6.2 0.0 7.1 10.1 1.9 2.0 160.8 53.4 16.8 5.2 4.6 18.0 98.6 KAT6A "MOZ, MYST3, RUNXBP2, ZC2HC6A, ZNF220" ENSG00000083168 "Lysine acetyltransferase 6A" Q92794 8 41929479-42051994 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, Repressor, Transferase" "Cancer-related genes, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017023, HPA063266, HPA065052" Supported Supported "Nucleoli,Nuclear speckles,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles" "Nucleoli, Cytosol" "CAB017023: , HPA063266: AB_2684973, HPA065052: AB_2685414" "unprognostic (3.51e-2)" "unprognostic (1.14e-1)" "unprognostic (2.04e-1)" "unprognostic (3.23e-2)" "unprognostic (2.28e-1)" "unprognostic (9.27e-3)" "unprognostic (3.61e-1)" "unprognostic (2.29e-1)" "unprognostic (2.95e-1)" "unprognostic (2.45e-2)" "unprognostic (1.50e-1)" "unprognostic (4.45e-2)" "unprognostic (4.20e-3)" "unprognostic (1.18e-1)" "unprognostic (2.24e-1)" "unprognostic (8.58e-2)" "unprognostic (2.95e-2)" 14.4 7.1 8.6 15.4 12.7 38.2 12.3 20.1 10.5 13.7 9.7 10.2 9.6 15.6 8.6 13.4 12.0 11.2 9.1 9.1 12.8 9.1 10.0 16.7 16.8 12.7 12.4 21.5 11.7 18.0 6.7 14.9 12.9 11.0 10.6 18.1 9.6 9.7 13.1 16.6 12.1 13.5 8.2 15.7 11.3 11.4 10.1 27.0 14.2 16.0 17.2 12.0 10.7 16.7 19.6 23.2 34.8 21.8 17.8 20.3 9.8 15.4 20.6 17.9 14.2 16.3 11.5 33.4 13.4 19.0 19.5 17.3 27.3 18.6 23.2 16.1 14.4 60.4 14.2 10.3 14.8 27.3 23.6 17.1 19.1 20.4 24.8 14.5 18.8 29.7 36.6 24.2 16.0 10.4 59.9 9.4 12.8 20.4 8.1 37.7 39.1 9.9 11.0 27.1 17.6 16.7 15.8 12.4 13.8 15.8 26.3 12.9 25.5 21.6 15.3 21.1 15.5 16.8 22.1 33.8 12.6 14.1 17.3 2.5 0.8 1.8 1.6 0.9 1.6 1.4 1.6 2.1 0.6 1.6 1.9 1.8 5.1 1.9 0.9 1.1 1.9 1.2 8.6 12.7 20.1 10.5 9.1 12.8 12.7 12.4 12.9 8.2 10.1 16.7 87.5 35.3 34.9 64.0 54.0 50.3 24.2 15.5 18.2 54.8 31.7 25.5 23.7 18.6 25.3 12.9 54.2 14.4 61.5 23.2 3.9 14.2 2.6 30.3 47.5 56.7 24.7 31.2 62.8 11.8 17.0 32.4 21.4 44.8 35.4 31.9 43.5 25.3 17.0 58.9 76.6 24.9 10.2 44.2 34.5 4.8 28.3 43.7 23.2 120.9 30.3 27.9 61.8 93.5 129.2 15.7 20.2 23.0 38.7 30.7 22.9 10.6 22.8 44.9 19.7 49.3 34.6 37.8 37.0 23.0 61.2 21.1 61.4 19.7 19.3 27.2 KAZN "C1orf196, FLJ43806, KAZRIN, KIAA1026" ENSG00000189337 "Kazrin, periplakin interacting protein" Q674X7 1 13892792-15118043 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 91.5" "Group enriched" "Detected in many" 12 "Excitatory neurons: 1065.9;Inhibitory neurons: 2872.7;Oligodendrocyte precursor cells: 1360.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 23 "neutrophil: 3.4" "Lineage enriched" "Detected in single" 23 "granulocytes: 3.4" "Cell line enhanced" "Detected in many" "AN3-CA: 85.6;SK-BR-3: 46.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032095, HPA032096" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nuclear speckles, Cytosol" "HPA032095: AB_2674146, HPA032096: AB_10670826" "unprognostic (2.81e-1)" "unprognostic (5.82e-2)" "unprognostic (1.12e-1)" "unprognostic (2.42e-3)" "unprognostic (5.34e-2)" "unprognostic (2.15e-3)" "unprognostic (6.57e-3)" "unprognostic (7.88e-3)" "unprognostic (3.21e-1)" "unprognostic (4.96e-3)" "unprognostic (1.10e-1)" "unprognostic (5.55e-2)" "prognostic favorable (1.20e-6)" "unprognostic (3.61e-2)" "unprognostic (7.93e-2)" "unprognostic (3.21e-1)" "unprognostic (1.06e-2)" 12.6 17.7 27.3 3.0 31.5 0.6 11.4 43.6 33.6 17.0 23.9 5.5 5.1 4.2 12.2 34.9 12.6 7.7 6.9 25.0 24.1 24.9 5.8 16.5 1.0 37.1 32.9 16.7 9.2 29.5 5.1 6.3 32.7 7.5 3.9 12.9 21.4 7.4 1.4 23.5 5.3 3.6 29.2 91.5 5.1 4.5 34.1 1.9 10.3 1.6 5.5 8.9 21.3 47.1 17.7 3.0 18.5 85.6 7.9 8.2 6.3 8.3 6.9 15.0 10.8 4.0 9.3 0.0 21.1 17.8 2.7 6.3 4.3 13.5 7.5 0.5 8.4 10.1 10.2 26.6 5.8 0.0 5.0 11.6 17.7 3.5 2.3 6.8 0.1 2.5 4.2 19.8 12.2 12.8 0.1 1.1 5.1 7.9 2.6 6.0 0.4 10.6 25.5 5.4 9.8 7.1 1.5 46.3 33.0 10.5 2.8 6.7 0.0 12.4 11.6 19.8 10.1 3.3 3.0 0.0 11.6 17.4 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 27.3 31.5 43.6 33.6 25.0 24.1 37.1 32.9 32.7 29.2 34.1 47.1 17.6 3.2 1.8 124.1 0.9 50.3 16.6 9.7 31.3 12.4 23.0 27.9 3.4 4.3 9.1 49.7 8.4 1.5 0.9 12.3 17.6 2.0 6.8 51.4 15.8 19.4 7.1 0.0 1065.9 1.6 8.1 27.0 3.6 16.8 3.8 9.7 31.1 0.1 0.8 0.0 2872.7 5.2 18.3 0.9 11.4 9.1 19.0 1.1 46.2 93.7 0.0 74.2 4.1 1360.7 143.5 1.5 1.6 17.3 0.3 19.4 2.0 12.9 30.3 3.2 6.6 33.5 23.6 0.3 3.2 26.2 90.4 46.4 1.4 41.6 3.5 24.8 KIF22 "Kid, KNSL4, OBP-1, OBP-2" ENSG00000079616 "Kinesin family member 22" Q14807 16 29790719-29805384 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA-binding, Motor protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 88.5;lymphoid tissue: 73.0" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 288.7;Hepatocytes: 565.5;Proximal tubular cells: 194.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048213, HPA075670" Enhanced Supported "Nuclear speckles" NA Yes "Cluster 44: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 14: REH - Unknown function" "Cluster 2: Hepatocytes - Metabolism" "Nuclear speckles" "HPA048213: AB_2680316, HPA075670: " "unprognostic (3.71e-2)" "prognostic favorable (3.87e-8)" "unprognostic (1.86e-1)" "unprognostic (2.21e-3)" "unprognostic (1.25e-1)" "unprognostic (6.06e-3)" "unprognostic (5.06e-3)" "unprognostic (2.70e-1)" "unprognostic (2.70e-1)" "unprognostic (4.73e-2)" "unprognostic (7.84e-2)" "unprognostic (2.10e-2)" "unprognostic (2.21e-2)" "unprognostic (3.67e-2)" "unprognostic (2.62e-1)" "unprognostic (3.94e-2)" "unprognostic (1.67e-1)" 9.2 7.0 9.5 19.7 9.9 88.5 13.4 8.1 10.4 10.5 6.9 22.6 16.6 8.2 8.6 22.3 12.3 6.4 10.8 9.5 8.9 11.2 8.3 8.5 34.1 8.4 8.3 8.2 7.3 33.8 9.2 15.7 8.3 24.9 20.6 8.9 10.5 12.0 8.4 32.8 16.9 8.0 8.9 18.6 11.8 28.3 9.4 73.0 26.0 11.0 34.7 10.1 13.3 9.3 89.3 103.9 120.6 87.6 8.0 11.9 104.8 65.8 52.1 123.1 113.9 97.9 103.3 130.6 60.4 34.4 61.2 90.0 118.9 67.5 57.4 84.8 100.4 72.4 115.1 119.0 2.7 79.1 76.0 6.7 17.7 68.5 51.3 17.1 67.2 144.7 109.4 104.1 65.5 186.5 173.1 196.1 101.8 65.7 59.6 237.9 110.6 122.4 44.9 45.0 99.8 65.4 48.5 94.7 33.1 39.4 84.8 105.2 29.8 63.8 66.6 57.7 72.6 96.6 105.3 141.4 41.9 129.0 83.3 58.7 14.1 39.5 49.7 21.1 37.3 30.4 50.0 53.1 14.7 27.3 40.0 38.4 6.2 31.5 18.3 9.6 56.5 40.5 9.5 9.9 8.1 10.4 9.5 8.9 8.4 8.3 8.3 8.9 9.4 9.3 13.9 32.1 115.4 5.5 23.0 30.8 25.8 56.7 52.9 27.5 56.5 56.4 288.7 57.2 38.5 69.9 25.0 81.7 20.1 44.2 62.6 16.6 9.9 29.5 18.9 29.2 41.4 85.2 4.8 50.1 85.4 50.1 25.0 31.1 43.6 29.5 49.2 565.5 46.3 6.7 6.1 39.5 34.6 47.7 40.4 8.5 15.5 36.7 35.6 4.7 38.6 69.8 29.9 4.0 5.3 17.3 44.0 12.8 49.9 26.1 18.0 194.0 29.7 20.5 13.1 23.7 34.2 50.9 61.6 41.4 27.6 76.9 34.2 12.2 42.3 22.5 KLF15 KKLF ENSG00000163884 "Kruppel like factor 15" Q9UIH9 3 126342635-126357408 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 92.5" "Cell type enhanced" "Detected in many" "Astrocytes: 22.9;Cardiomyocytes: 29.7;Distal tubular cells: 29.4;Hepatocytes: 66.9;Peritubular cells: 19.9;Proximal tubular cells: 22.1" "Cancer enhanced" "Detected in many" "liver cancer: 30.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 57.4;HHSteC: 34.8;RPMI-8226: 20.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003286, HPA028866" Uncertain Supported "Nucleoplasm,Nuclear speckles,Vesicles" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" "Nucleoplasm, Nuclear speckles" Vesicles "HPA003286: , HPA028866: AB_10600819" "unprognostic (3.77e-3)" "unprognostic (1.08e-1)" "unprognostic (1.99e-2)" "unprognostic (1.07e-2)" "unprognostic (2.72e-3)" "unprognostic (2.11e-1)" "unprognostic (4.63e-2)" "unprognostic (1.09e-2)" "unprognostic (2.91e-1)" "unprognostic (1.32e-1)" "unprognostic (3.58e-2)" "unprognostic (1.10e-1)" "prognostic favorable (3.27e-7)" "unprognostic (6.75e-2)" "unprognostic (7.65e-2)" "unprognostic (1.91e-2)" "unprognostic (5.58e-3)" 36.5 6.2 42.2 0.8 50.7 0.1 25.4 45.1 69.5 15.8 37.5 18.6 1.2 19.1 4.1 7.1 29.7 3.5 31.4 41.7 40.6 20.3 92.5 18.6 1.8 64.9 45.9 46.3 48.5 4.5 10.4 1.7 47.2 17.6 0.9 3.9 19.7 5.2 67.3 10.3 10.2 2.5 44.9 3.6 30.2 5.6 44.7 1.2 11.1 32.4 0.8 27.0 12.0 48.4 0.8 0.0 2.2 9.2 57.4 1.0 10.0 0.6 1.4 0.7 1.3 1.1 0.0 3.4 0.9 0.0 1.7 0.1 5.3 0.1 0.2 0.2 2.0 0.1 0.8 7.9 34.8 0.0 0.2 5.4 0.5 0.0 1.2 0.0 0.6 4.5 4.3 7.4 0.2 0.7 0.0 1.3 6.6 1.3 0.3 4.7 0.2 20.2 0.1 0.8 0.7 7.7 0.1 0.3 10.2 3.3 0.5 4.6 0.3 0.3 0.4 0.3 0.3 4.7 0.6 0.7 0.2 1.5 1.3 25.1 7.6 10.3 7.0 10.2 8.2 12.3 7.3 7.4 8.2 11.4 9.4 11.3 16.7 12.8 9.3 9.0 10.5 11.7 42.2 50.7 45.1 69.5 41.7 40.6 64.9 45.9 47.2 44.9 44.7 48.4 1.5 6.4 4.6 22.9 0.8 0.0 2.9 0.2 0.6 1.3 7.8 1.8 29.7 15.7 0.7 0.0 0.0 0.1 0.1 0.0 29.4 0.1 0.1 2.5 4.4 2.1 0.0 2.7 0.6 0.0 0.2 8.1 3.1 3.4 0.0 13.7 8.2 66.9 0.1 0.0 2.8 0.1 0.0 2.6 0.0 0.8 12.2 0.4 1.8 2.8 0.0 12.0 0.0 15.1 5.7 0.4 0.0 19.9 0.9 5.2 0.0 22.1 0.8 3.3 0.0 12.0 5.5 0.1 0.1 0.3 0.0 0.3 0.5 0.6 0.1 1.8 LHPP HDHD2B ENSG00000107902 "Phospholysine phosphohistidine inorganic pyrophosphate phosphatase" Q9H008 10 124461823-124617888 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 198.8;choroid plexus: 104.0" "Cell type enhanced" "Detected in many" "Early spermatids: 114.9;Late spermatids: 163.3;Proximal tubular cells: 93.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009163, HPA009269" Enhanced Supported "Nuclear speckles,Cytosol" NA NA 820000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 70: Brain - Nervous system development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles, Cytosol" "HPA009163: AB_1079250, HPA009269: AB_1079249" "unprognostic (3.46e-2)" "unprognostic (1.23e-2)" "unprognostic (4.78e-2)" "unprognostic (3.89e-1)" "unprognostic (2.14e-1)" "unprognostic (1.96e-1)" "unprognostic (5.77e-3)" "unprognostic (2.02e-2)" "unprognostic (3.58e-1)" "unprognostic (1.93e-1)" "unprognostic (6.42e-2)" "unprognostic (5.55e-2)" "unprognostic (1.79e-3)" "unprognostic (2.52e-1)" "unprognostic (2.10e-1)" "unprognostic (1.98e-1)" "unprognostic (1.64e-1)" 12.9 32.0 135.1 8.2 173.7 10.5 13.0 159.3 190.6 18.5 104.0 27.1 23.4 20.2 13.4 24.1 10.0 10.2 17.5 129.7 156.5 28.4 60.2 9.2 11.8 179.2 165.8 9.0 15.9 9.2 14.5 8.6 170.7 14.0 8.5 7.5 18.3 12.5 10.2 15.3 21.1 10.2 151.1 14.0 20.1 24.2 156.3 9.7 29.4 4.8 15.2 14.7 16.1 198.8 24.7 12.0 4.7 12.1 18.2 14.7 12.8 8.2 18.0 5.5 10.0 2.1 22.4 24.4 19.7 13.5 6.1 26.1 1.4 4.7 5.7 5.4 16.3 17.6 4.1 11.4 18.5 3.6 27.6 11.0 20.0 5.4 13.0 16.0 8.8 21.4 8.9 9.5 6.9 24.5 12.0 11.3 8.5 10.4 6.8 12.4 5.3 31.8 12.1 3.2 2.7 14.2 6.3 22.6 8.2 6.5 17.2 0.6 4.2 8.5 12.2 7.2 2.3 7.9 2.5 7.8 7.7 6.8 2.0 8.1 28.8 25.3 16.1 24.5 20.8 41.0 18.7 17.2 35.6 43.3 22.4 16.0 4.8 7.9 29.0 13.4 32.1 24.4 135.1 173.7 159.3 190.6 129.7 156.5 179.2 165.8 170.7 151.1 156.3 198.8 5.0 3.2 14.8 22.9 29.1 7.4 9.4 22.1 13.1 6.0 19.8 19.8 15.8 12.8 19.4 7.3 0.0 54.2 6.2 17.9 33.2 5.3 114.9 17.7 12.7 4.6 9.5 19.8 29.4 2.3 24.7 11.2 19.9 8.2 10.8 23.3 6.1 61.1 26.5 11.8 27.8 21.3 24.4 16.0 8.1 163.3 5.9 12.9 17.8 8.4 15.6 9.8 8.2 15.6 76.4 3.3 30.2 10.5 19.7 6.7 80.5 93.8 24.9 6.4 13.1 5.2 9.5 33.1 11.3 30.7 5.4 24.2 12.1 12.4 23.0 16.3 LIMK1 LIMK ENSG00000106683 "LIM domain kinase 1" P53667 7 74082933-74122525 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 77.9" "Cell type enhanced" "Detected in many" "Granulosa cells: 27.6;Horizontal cells: 35.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-87 MG: 136.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028516, HPA073571" Approved Supported "Nuclear speckles,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 70: Brain - Nervous system development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 4: Macrophages - Innate immune response" "Nuclear speckles, Cytosol" "HPA028516: AB_10601751, HPA073571: " "unprognostic (1.45e-2)" "unprognostic (2.75e-1)" "prognostic unfavorable (4.95e-5)" "unprognostic (2.77e-2)" "unprognostic (1.40e-3)" "unprognostic (3.35e-2)" "prognostic unfavorable (7.79e-6)" "unprognostic (1.90e-2)" "unprognostic (2.16e-1)" "unprognostic (1.18e-1)" "unprognostic (3.32e-2)" "unprognostic (3.16e-2)" "prognostic unfavorable (6.63e-8)" "unprognostic (4.14e-2)" "unprognostic (7.00e-2)" "unprognostic (3.84e-2)" "unprognostic (5.79e-2)" 11.1 10.5 31.1 18.7 32.7 6.8 9.4 28.3 77.9 21.4 0.2 8.9 6.6 13.1 3.5 11.3 7.3 10.1 9.4 35.0 43.8 10.8 4.6 13.2 23.5 75.5 40.0 13.2 11.4 5.8 13.9 7.3 73.0 12.3 4.1 4.0 17.9 8.2 23.7 11.4 12.1 7.1 31.8 22.3 9.2 15.6 59.1 8.1 11.2 7.8 18.2 13.1 14.7 38.3 47.4 37.2 27.2 45.4 35.1 47.0 20.0 28.8 27.3 22.6 25.4 21.3 45.6 30.2 12.7 35.5 76.9 28.1 10.1 17.8 8.6 53.7 18.6 23.2 13.1 24.6 40.5 17.2 81.4 46.8 15.6 18.5 9.6 68.3 34.4 20.9 15.1 9.0 28.8 41.4 14.8 31.4 52.1 16.6 23.7 21.1 43.3 18.2 26.5 10.1 10.7 25.2 18.6 43.7 23.5 29.7 13.9 15.4 41.1 36.0 33.7 94.5 47.7 10.2 12.5 54.9 136.5 12.4 25.2 0.1 6.1 3.5 1.8 6.0 1.4 3.4 0.4 1.2 7.0 1.7 0.1 0.5 0.5 5.8 3.8 0.7 0.3 3.3 31.1 32.7 28.3 77.9 35.0 43.8 75.5 40.0 73.0 31.8 59.1 38.3 2.9 3.2 2.7 7.5 14.4 2.9 5.2 6.6 1.8 6.6 7.7 6.9 3.4 7.2 3.8 1.8 2.1 2.5 11.9 2.9 0.0 6.6 1.2 2.7 9.7 4.1 2.4 0.4 15.4 6.5 6.3 9.2 3.1 5.1 5.7 27.6 3.3 2.1 25.0 35.3 20.8 2.7 0.0 13.5 10.8 2.2 7.2 15.6 3.6 6.5 14.9 3.5 22.6 6.6 2.4 13.5 2.3 6.0 10.0 9.0 0.3 2.8 3.1 3.3 0.0 5.3 4.5 3.4 11.5 1.8 3.1 3.7 11.1 6.9 2.4 7.2 LMNA "CMD1A, HGPS, LGMD1B, LMN1, LMNL1, MADA, PRO1" ENSG00000160789 "Lamin A/C" P02545 1 156082573-156140081 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Cardiomyopathy, Charcot-Marie-Tooth disease, Congenital muscular dystrophy, Disease variant, Emery-Dreifuss muscular dystrophy, Limb-girdle muscular dystrophy, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 1533.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 85.1;T-reg: 83.2" "Group enriched" "Detected in all" 8 "dendritic cells: 85.1;granulocytes: 23.9;T-cells: 83.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004022, HPA006523, HPA006660" Supported Supported "Nuclear speckles" NA NA 5700000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 17: WM-115 - Nervous system development" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles" "CAB004022: AB_2136278, HPA006523: , HPA006660: AB_1079231" "unprognostic (2.22e-2)" "unprognostic (1.89e-1)" "unprognostic (1.04e-2)" "unprognostic (5.75e-2)" "unprognostic (7.43e-3)" "unprognostic (1.47e-1)" "unprognostic (5.23e-3)" "unprognostic (3.27e-2)" "unprognostic (8.33e-2)" "unprognostic (5.90e-2)" "unprognostic (5.10e-2)" "unprognostic (6.34e-2)" "unprognostic (1.41e-2)" "unprognostic (1.24e-1)" "unprognostic (2.89e-1)" "unprognostic (3.08e-2)" "unprognostic (1.44e-2)" 280.2 174.8 17.6 64.9 27.1 58.1 231.5 24.1 20.6 221.7 33.0 183.3 72.8 271.4 14.5 256.2 173.8 92.1 221.7 15.8 23.1 120.9 93.2 188.5 18.2 30.3 25.2 178.2 81.8 21.3 76.9 53.0 26.1 125.3 38.2 4.7 176.1 42.8 190.0 364.3 136.8 78.8 21.0 84.1 160.6 61.9 30.9 15.3 147.4 23.8 22.9 168.7 217.6 41.8 518.8 269.7 26.2 72.4 119.5 238.7 169.4 607.3 379.6 221.3 146.8 68.3 311.9 2.8 338.7 417.9 94.6 515.4 31.4 227.8 70.3 188.6 50.8 175.4 168.4 130.8 124.0 25.7 412.9 133.0 92.0 154.8 134.7 120.2 207.5 0.7 82.8 21.9 205.8 193.1 1.0 67.8 32.1 202.9 706.0 1.6 195.9 137.7 128.9 105.6 33.8 114.9 414.3 154.2 427.4 56.2 230.1 74.2 727.9 241.6 233.0 389.1 393.3 39.5 10.5 4.9 449.2 24.8 760.4 23.9 8.3 0.4 2.8 2.1 2.5 2.4 17.8 7.3 85.1 0.2 0.2 0.7 2.1 3.7 0.2 0.3 83.2 14.6 17.6 27.1 24.1 20.6 15.8 23.1 30.3 25.2 26.1 21.0 30.9 41.8 353.5 262.8 350.0 16.0 179.1 610.5 1235.3 446.2 531.6 7.2 542.5 374.9 94.1 191.6 320.3 161.8 47.9 478.8 239.8 614.1 109.5 429.3 38.6 215.4 209.4 386.0 431.5 70.4 9.9 360.2 387.8 622.1 505.1 270.5 1181.8 145.5 277.7 103.1 343.0 13.5 15.1 601.2 177.0 60.6 1533.4 45.4 288.6 409.0 859.2 10.3 20.4 37.2 3.1 17.1 20.1 513.0 384.1 287.3 331.3 340.6 262.6 125.0 170.5 17.8 203.8 1028.4 766.8 107.4 42.2 404.1 602.4 680.9 472.3 111.6 513.8 942.6 LPXN LDPL ENSG00000110031 Leupaxin O60711 11 58526871-58578220 "Predicted intracellular proteins" "Cell adhesion, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 118.5" "Cell type enhanced" "Detected in many" "B-cells: 75.9;dendritic cells: 80.7;Langerhans cells: 154.6;Macrophages: 81.7;Plasma cells: 82.2;T-cells: 90.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 200.7;HMC-1: 329.3;Karpas-707: 285.0;U-2197: 199.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043741, CAB046478, HPA061441" Enhanced Supported "Nuclear speckles,Focal adhesion sites,Cytosol" No No "Cluster 13: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "Focal adhesion sites" "Nuclear speckles, Cytosol" "CAB046478: AB_10603113, HPA043741: AB_2678647, HPA061441: AB_2684518" "unprognostic (1.61e-3)" "unprognostic (6.91e-2)" "unprognostic (6.54e-2)" "prognostic favorable (8.81e-4)" "unprognostic (5.16e-2)" "unprognostic (2.07e-3)" "unprognostic (2.16e-2)" "unprognostic (8.87e-3)" "unprognostic (5.18e-2)" "unprognostic (3.96e-2)" "unprognostic (2.39e-2)" "unprognostic (3.05e-1)" "unprognostic (3.60e-3)" "unprognostic (1.91e-1)" "unprognostic (5.25e-2)" "unprognostic (2.55e-1)" "unprognostic (2.41e-3)" 10.4 8.3 7.5 48.3 8.2 10.2 10.2 7.8 11.8 7.9 4.5 14.5 10.9 7.4 11.9 5.2 7.6 15.1 5.3 7.1 7.8 10.6 14.0 33.5 87.1 9.1 8.8 9.5 8.6 6.5 7.2 5.2 10.2 9.4 19.6 7.0 11.0 7.1 3.8 5.9 26.2 9.7 8.6 44.1 13.0 10.2 10.0 103.3 10.2 5.1 118.5 32.4 6.0 10.9 1.7 2.1 2.0 3.9 7.4 9.3 1.4 50.5 200.7 12.4 22.0 0.4 5.1 149.8 2.0 61.9 9.2 2.0 1.7 137.7 51.4 65.4 0.9 6.8 1.3 1.0 12.8 41.1 329.3 7.2 3.2 170.8 22.0 12.0 80.9 90.0 1.9 285.0 101.5 1.1 144.8 51.6 1.6 2.3 45.8 2.1 2.5 129.2 8.3 71.2 1.0 1.6 2.2 3.2 20.1 2.8 2.7 11.7 79.8 30.8 9.5 199.5 45.9 18.4 18.9 146.5 71.6 36.8 71.6 6.3 74.3 12.2 101.3 41.8 148.9 71.9 102.9 117.6 137.5 46.2 79.6 95.9 14.1 79.2 22.2 124.4 152.1 98.8 7.5 8.2 7.8 11.8 7.1 7.8 9.1 8.8 10.2 8.6 10.0 10.9 4.1 0.0 6.7 22.9 75.9 9.7 6.6 7.2 3.4 4.1 4.0 4.7 2.3 4.3 2.8 0.0 4.2 2.8 80.7 4.2 3.9 2.5 23.0 2.8 1.9 5.9 6.1 13.3 18.2 5.6 1.3 6.6 13.3 2.3 51.5 5.4 2.5 7.6 44.0 1.7 19.8 3.1 6.1 63.7 154.6 8.7 1.8 81.7 19.6 30.0 52.9 2.8 49.4 11.6 27.3 4.1 5.2 3.8 82.2 3.6 6.9 5.7 4.3 4.4 6.6 3.6 3.8 9.2 4.2 2.6 9.7 2.5 90.3 2.9 5.2 27.6 MAML3 "CAGH3, GDN, KIAA1816, MAM2, TNRC3" ENSG00000196782 "Mastermind like transcriptional coactivator 3" Q96JK9 4 139716753-140154184 "Predicted intracellular proteins" "Notch signaling pathway, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 125.6;Microglial cells: 355.1;Oligodendrocytes: 150.8" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 5 "cerebellum: 16.8" "Immune cell enhanced" "Detected in many" "basophil: 12.2" "Group enriched" "Detected in many" 5 "granulocytes: 12.2;NK-cells: 3.4" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 15.0;SCLC-21H: 15.7;SH-SY5Y: 23.9;WM-115: 20.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA037717 Approved Supported "Nuclear speckles" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 21: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear speckles" "HPA037717: AB_10794323" "unprognostic (1.83e-1)" "unprognostic (1.28e-1)" "unprognostic (1.17e-1)" "unprognostic (7.83e-3)" "unprognostic (4.73e-2)" "unprognostic (2.63e-1)" "unprognostic (3.36e-2)" "unprognostic (1.35e-1)" "unprognostic (1.48e-1)" "unprognostic (3.89e-1)" "unprognostic (5.52e-3)" "unprognostic (1.73e-1)" "prognostic favorable (7.60e-5)" "unprognostic (3.38e-1)" "unprognostic (1.20e-1)" "unprognostic (7.22e-2)" "unprognostic (2.88e-1)" 3.3 3.4 1.5 2.4 0.9 3.2 3.4 16.8 2.1 5.0 0.1 3.8 4.8 6.7 5.3 5.9 5.5 4.1 2.0 2.2 2.8 2.0 2.6 3.8 2.6 3.4 2.3 8.6 6.8 3.3 4.5 5.0 3.4 4.9 3.9 1.7 5.9 4.5 1.7 7.8 4.5 6.0 2.4 3.3 3.4 3.0 2.2 6.0 4.3 2.1 2.3 3.6 5.1 2.2 0.5 8.1 5.4 2.7 2.1 4.4 4.9 1.0 4.4 0.5 0.3 3.2 2.2 1.8 0.4 0.8 0.3 0.1 2.1 1.8 0.3 0.0 1.2 5.9 1.9 0.3 0.4 2.8 8.7 4.3 1.5 0.1 0.9 3.3 15.0 0.1 1.6 0.0 0.3 0.9 0.5 1.2 1.4 3.6 3.5 3.5 0.5 3.6 2.5 11.2 15.7 23.9 0.0 4.2 5.5 4.2 2.3 0.8 13.1 0.6 1.3 0.1 1.7 2.9 3.5 0.1 0.8 9.2 20.2 12.2 1.5 2.9 0.0 1.1 0.1 0.0 0.0 0.0 1.5 0.4 0.4 0.4 3.6 3.4 0.9 1.2 0.0 1.2 1.5 0.9 16.8 2.1 2.2 2.8 3.4 2.3 3.4 2.4 2.2 2.2 21.2 3.2 11.5 39.5 3.1 8.0 8.1 4.2 7.4 4.6 12.6 9.3 3.0 11.5 8.7 5.5 18.8 5.8 3.9 13.6 5.9 5.1 3.6 12.6 9.4 11.7 14.9 9.4 60.2 5.1 7.3 5.3 8.6 19.9 19.6 34.4 13.2 17.5 7.5 11.8 125.6 12.1 2.0 22.6 13.3 9.0 4.1 19.6 3.6 355.1 18.3 3.1 1.0 7.5 150.8 3.0 14.0 3.8 2.1 5.7 8.2 6.1 7.2 3.7 0.0 2.9 13.7 0.5 2.2 19.0 13.5 8.2 5.3 8.5 11.0 8.9 MAPK1 "ERK, ERK2, MAPK2, p41mapk, PRKM1, PRKM2" ENSG00000100030 "Mitogen-activated protein kinase 1" P28482 22 21759657-21867680 "Cancer-related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Kinase, Repressor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 341.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003995, CAB004229, HPA005700, HPA030069, CAB079930, CAB079932, CAB079933" Enhanced Supported "Nuclear speckles,Cytosol" NA NA 140000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 65: Brain - Ion transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Nuclear speckles" "CAB004229: AB_627547, CAB079930: , CAB079932: , CAB079933: , HPA003995: AB_1078751, HPA005700: AB_1078750, HPA030069: AB_10602035" "unprognostic (9.41e-3)" "unprognostic (2.68e-1)" "unprognostic (2.50e-3)" "unprognostic (4.17e-1)" "unprognostic (4.44e-3)" "unprognostic (1.72e-1)" "prognostic unfavorable (4.95e-4)" "unprognostic (2.29e-1)" "unprognostic (1.67e-1)" "unprognostic (1.58e-1)" "unprognostic (8.43e-3)" "unprognostic (1.04e-1)" "unprognostic (1.35e-2)" "unprognostic (2.08e-1)" "unprognostic (1.94e-1)" "unprognostic (1.41e-1)" "unprognostic (6.49e-2)" 31.1 33.1 64.8 35.9 84.4 41.2 29.8 37.3 80.9 31.4 32.9 36.1 25.8 29.6 30.1 43.0 29.0 28.9 42.2 91.3 46.4 42.1 34.2 38.5 36.8 29.1 45.1 29.2 38.1 51.7 12.0 33.1 35.9 32.8 36.2 30.3 28.9 32.7 38.1 45.0 29.5 39.1 43.8 40.5 33.9 43.7 60.1 44.4 46.1 41.9 41.9 35.5 18.9 43.2 78.7 48.0 60.5 37.2 75.9 76.7 25.9 84.7 77.5 73.2 72.0 43.8 40.8 45.8 41.3 112.7 67.5 74.6 73.9 67.9 97.8 180.4 72.1 78.9 43.0 67.7 73.5 113.2 80.5 56.9 60.1 89.4 81.6 58.0 101.7 45.4 341.9 50.5 97.5 36.6 72.0 38.5 24.4 104.5 46.8 79.4 149.6 13.2 55.5 62.9 50.0 28.6 91.5 64.2 57.2 60.4 42.4 47.1 90.1 61.5 79.6 71.9 54.2 47.1 59.4 65.8 60.0 60.0 68.4 1.4 4.9 7.2 15.9 6.0 4.9 2.3 3.6 6.0 4.1 2.6 3.5 6.1 16.5 9.3 6.9 4.0 3.4 4.0 64.8 84.4 37.3 80.9 91.3 46.4 29.1 45.1 35.9 43.8 60.1 43.2 36.8 48.1 35.8 97.6 44.0 60.2 28.4 25.1 28.5 25.5 32.5 24.5 41.5 42.9 31.2 51.5 54.2 21.8 151.7 74.4 19.6 28.5 49.0 33.5 40.3 39.9 59.6 63.8 109.2 39.2 23.2 38.4 52.0 45.0 92.8 28.8 52.1 63.5 53.2 28.6 91.2 42.2 26.4 89.0 77.1 14.7 32.6 74.9 40.9 68.4 75.0 35.8 143.2 82.4 75.1 45.3 35.2 44.4 37.0 43.8 32.8 46.0 32.2 22.4 32.9 44.6 37.3 74.1 53.4 44.9 61.8 19.2 91.4 43.3 38.6 38.8 MAPK14 "CSBP1, CSBP2, CSPB1, Mxi2, p38, PRKM14, PRKM15" ENSG00000112062 "Mitogen-activated protein kinase 14" Q16539 6 36027677-36111236 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 104.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 79.0;neutrophil: 24.9" "Lineage enriched" "Detected in all" 7 "granulocytes: 79.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010285, CAB040578, HPA051825" Approved Supported "Nuclear speckles,Cytosol" NA NA 970000 "Cluster 38: Basophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nuclear speckles" Cytosol "CAB010285: AB_632140, CAB040578: , HPA051825: " "unprognostic (6.76e-3)" "unprognostic (6.28e-2)" "unprognostic (6.30e-3)" "unprognostic (3.30e-3)" "unprognostic (6.98e-2)" "unprognostic (4.04e-2)" "unprognostic (8.10e-2)" "unprognostic (1.93e-1)" "unprognostic (2.20e-3)" "unprognostic (8.39e-2)" "unprognostic (6.27e-2)" "unprognostic (1.10e-1)" "unprognostic (1.47e-2)" "unprognostic (3.66e-3)" "unprognostic (6.66e-2)" "unprognostic (3.25e-1)" "unprognostic (1.58e-1)" 29.9 26.1 15.2 31.5 16.5 89.3 23.8 19.2 17.1 30.8 19.3 26.6 27.9 37.2 15.8 32.3 25.7 23.5 25.7 17.2 18.2 23.9 41.4 28.3 28.0 11.5 11.7 22.2 18.3 20.6 19.3 44.6 12.1 19.6 29.0 14.8 21.0 24.4 33.5 34.4 26.2 39.0 13.0 44.9 22.5 9.1 18.1 38.6 31.1 31.9 33.3 32.3 29.2 13.8 49.7 26.7 28.3 44.9 60.0 59.8 62.2 50.2 64.8 58.7 60.3 67.3 24.8 40.4 49.6 54.9 28.0 34.8 47.2 43.7 60.9 47.3 37.6 94.9 37.2 53.1 33.2 60.3 54.9 43.1 40.5 42.2 40.9 47.6 67.1 67.2 52.4 49.1 40.3 21.1 62.2 62.5 17.0 29.9 26.2 71.7 45.5 37.5 38.5 67.6 21.8 17.2 46.0 33.5 50.3 34.1 40.8 99.9 47.9 52.5 29.8 33.6 47.7 24.3 59.8 39.5 23.2 112.1 43.9 79.0 10.3 6.3 4.5 7.2 5.5 3.1 4.4 5.1 8.2 5.3 4.6 4.7 24.9 6.1 10.8 4.0 5.8 5.1 15.2 16.5 19.2 17.1 17.2 18.2 11.5 11.7 12.1 13.0 18.1 13.8 24.4 32.1 13.9 37.2 22.6 15.9 11.0 13.9 28.5 18.9 14.0 11.7 25.0 14.3 18.5 18.4 31.3 45.4 26.8 29.0 1.9 13.9 3.6 18.7 25.8 22.6 16.8 47.1 104.9 11.3 18.7 25.9 21.9 30.7 21.0 17.7 28.9 52.9 25.3 11.8 79.2 25.4 10.2 51.7 24.9 5.2 24.5 38.5 10.6 52.5 58.7 10.9 39.1 46.8 69.6 22.8 16.2 26.7 27.7 10.3 33.7 17.2 20.9 22.5 13.1 20.4 15.7 9.9 8.5 27.1 19.0 23.9 28.0 12.3 18.8 10.7 MAPK9 "JNK2, p54a, PRKM9, SAPK" ENSG00000050748 "Mitogen-activated protein kinase 9" P45984 5 180233143-180292099 "Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 64.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 16.3" "Lineage enriched" "Detected in all" 6 "granulocytes: 16.3" "Cell line enhanced" "Detected in all" "HDLM-2: 211.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008910, HPA072462" Enhanced Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "Nuclear speckles" "CAB008910: , HPA072462: " "unprognostic (5.04e-3)" "unprognostic (2.06e-2)" "prognostic favorable (1.11e-4)" "unprognostic (8.53e-2)" "unprognostic (1.75e-1)" "unprognostic (5.06e-3)" "unprognostic (6.83e-3)" "unprognostic (3.16e-1)" "unprognostic (4.93e-2)" "unprognostic (3.76e-1)" "unprognostic (5.97e-2)" "unprognostic (1.36e-1)" "unprognostic (1.50e-1)" "unprognostic (2.13e-1)" "unprognostic (2.29e-1)" "unprognostic (9.38e-3)" "unprognostic (2.40e-1)" 19.3 21.1 28.4 18.4 32.6 21.3 17.5 36.5 41.4 17.7 7.2 22.4 18.5 15.3 16.2 15.4 15.3 13.9 25.7 34.2 25.8 21.1 17.7 19.5 19.9 25.7 19.7 14.6 45.7 30.1 12.9 19.7 26.4 20.0 26.4 21.4 19.1 21.6 40.8 11.7 19.3 19.9 16.9 16.6 22.5 17.8 22.2 22.5 26.7 34.8 21.1 17.4 11.1 29.8 52.7 42.7 37.0 46.5 35.7 39.3 79.4 49.6 43.5 40.5 40.5 56.4 36.7 55.9 83.1 52.6 89.3 39.6 38.4 82.8 47.5 211.8 36.9 23.2 46.8 40.3 27.1 49.0 39.2 29.3 36.5 39.5 38.0 42.5 48.9 43.0 26.2 39.5 55.9 68.9 49.2 20.4 25.8 64.8 25.0 46.9 62.7 26.9 30.8 49.7 42.5 29.9 58.2 55.8 40.4 45.8 56.9 41.7 35.5 48.3 49.2 69.3 75.2 28.2 35.6 37.9 51.5 44.8 32.9 16.3 0.5 2.2 1.6 1.1 1.6 0.8 1.2 1.4 0.8 1.3 0.8 0.9 0.7 1.2 2.3 1.2 2.7 0.3 28.4 32.6 36.5 41.4 34.2 25.8 25.7 19.7 26.4 16.9 22.2 29.8 20.5 32.1 14.4 26.1 10.5 10.1 7.0 6.5 9.1 21.9 16.8 12.2 27.6 12.8 8.5 9.2 16.7 15.3 20.5 20.7 5.9 8.0 1.2 17.6 14.2 12.2 16.7 9.5 62.5 16.0 23.3 11.1 15.8 18.6 11.4 14.5 12.5 16.7 11.7 13.5 64.3 17.9 4.1 24.2 20.5 3.1 10.5 15.0 5.4 31.9 13.9 11.4 15.5 25.1 32.9 13.1 12.3 13.5 15.6 10.2 13.4 11.0 6.9 14.8 13.1 13.5 13.7 17.0 17.1 9.4 11.4 17.8 14.7 8.2 15.4 8.8 MBD4 MED1 ENSG00000129071 "Methyl-CpG binding domain 4, DNA glycosylase" O95243 3 129430947-129440179 "Cancer-related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Hydrolase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002031 Supported Supported "Nuclear speckles" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Nuclear speckles" "HPA002031: AB_1079319" "unprognostic (2.70e-2)" "unprognostic (3.48e-3)" "unprognostic (1.18e-2)" "unprognostic (6.37e-2)" "unprognostic (4.31e-2)" "unprognostic (7.11e-2)" "unprognostic (4.70e-2)" "unprognostic (3.25e-2)" "unprognostic (2.02e-2)" "unprognostic (5.73e-2)" "prognostic unfavorable (2.18e-4)" "prognostic unfavorable (4.75e-4)" "prognostic unfavorable (2.73e-6)" "unprognostic (9.27e-2)" "unprognostic (1.59e-2)" "unprognostic (8.58e-2)" "unprognostic (3.35e-2)" 18.6 18.4 16.8 34.0 18.4 44.2 21.6 19.6 20.7 33.2 16.8 19.3 23.7 23.3 24.8 16.4 19.3 21.3 25.3 17.0 17.4 25.4 38.0 22.9 66.5 17.5 17.2 30.3 22.9 18.1 19.3 19.7 17.7 18.7 22.9 19.6 19.5 17.8 25.8 23.7 27.5 19.7 17.3 39.2 27.8 17.3 18.4 30.0 19.3 22.3 74.0 18.5 17.5 20.6 46.2 27.4 32.5 36.5 36.8 32.8 37.5 39.0 36.9 36.7 43.3 33.8 30.1 64.6 31.1 24.5 33.7 40.7 25.2 24.1 44.2 37.0 16.6 38.9 32.0 24.6 58.7 71.2 49.2 39.1 33.8 31.2 27.4 36.5 35.1 37.2 43.9 47.1 27.5 43.3 41.4 50.0 28.7 38.8 23.5 38.7 19.2 44.7 40.9 22.7 36.5 20.3 49.3 25.3 42.5 28.0 32.3 62.5 23.6 34.5 26.3 37.6 26.2 31.9 20.9 111.9 29.4 40.1 29.2 80.3 25.0 35.2 31.1 23.1 24.0 116.5 33.2 30.9 21.0 110.8 40.6 33.3 43.0 28.9 30.0 25.2 31.5 25.6 16.8 18.4 19.6 20.7 17.0 17.4 17.5 17.2 17.7 17.3 18.4 20.6 36.5 19.2 52.9 15.3 111.2 17.3 32.5 38.4 29.6 37.0 26.7 29.6 35.9 27.1 36.4 44.1 18.8 49.2 61.4 22.4 45.0 32.1 19.8 49.6 41.2 33.5 33.6 46.3 18.1 69.0 46.2 35.6 55.0 45.0 58.9 33.1 31.4 32.1 71.8 21.9 12.8 27.5 40.7 41.8 24.7 10.6 32.9 48.0 21.4 24.4 62.9 21.2 54.6 14.1 22.0 39.3 23.4 36.5 75.5 31.1 29.4 55.5 39.5 46.3 39.5 39.6 30.9 49.5 71.6 30.4 19.6 37.1 54.2 33.2 26.3 35.6 MECOM "EVI1, KMT8E, MDS1, MDS1-EVI1, PRDM3" ENSG00000085276 "MDS1 and EVI1 complex locus" Q03112 3 169083499-169663775 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 73.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 184.8;Collecting duct cells: 125.0;Gastric mucus-secreting cells: 111.1;Glandular and luminal cells: 107.7;Microglial cells: 346.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 55.5;RPTEC TERT1: 71.2;RT4: 119.6;TIME: 53.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046537 Supported Supported "Nuclear speckles" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 46: Fibroblasts - ECM organization" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "Nuclear speckles" "HPA046537: AB_2679689" "unprognostic (4.09e-2)" "unprognostic (1.96e-1)" "unprognostic (3.24e-3)" "unprognostic (7.29e-2)" "unprognostic (2.87e-2)" "unprognostic (2.53e-1)" "unprognostic (1.83e-2)" "unprognostic (4.77e-3)" "unprognostic (1.53e-2)" "unprognostic (3.27e-3)" "prognostic unfavorable (2.59e-4)" "unprognostic (1.87e-1)" "unprognostic (2.60e-3)" "unprognostic (6.54e-2)" "unprognostic (1.03e-1)" "unprognostic (2.81e-2)" "unprognostic (3.37e-3)" 16.0 0.9 7.3 7.3 7.2 1.4 12.3 8.5 7.3 21.3 2.4 24.9 19.8 17.3 4.4 13.5 23.4 8.3 13.0 4.9 6.3 41.3 1.4 25.5 1.5 9.1 7.2 2.3 23.3 1.7 4.2 17.4 8.9 6.9 30.0 1.8 8.8 8.0 4.3 2.6 10.2 8.0 4.1 6.2 73.3 3.0 8.1 2.0 5.7 12.0 5.3 30.4 7.5 6.3 25.8 0.7 0.9 0.2 3.7 2.7 1.1 3.7 4.2 1.1 2.2 10.7 26.1 0.9 39.1 0.6 5.5 13.4 10.2 15.7 3.1 1.4 16.6 16.7 7.6 1.1 0.4 0.3 5.1 5.7 2.2 1.0 12.1 12.0 55.5 1.4 13.0 1.8 10.3 9.8 0.9 0.4 1.7 13.5 6.6 9.8 13.1 0.3 71.2 119.6 1.0 3.1 1.3 6.7 0.3 1.5 7.1 1.1 53.4 9.7 6.6 2.5 16.9 1.4 0.7 0.9 4.8 1.0 1.6 0.9 0.4 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.5 0.2 0.0 0.0 0.3 0.4 0.5 1.6 0.1 0.0 7.3 7.2 8.5 7.3 4.9 6.3 9.1 7.2 8.9 4.1 8.1 6.3 80.2 60.9 184.8 16.0 0.6 2.2 33.3 29.4 10.2 0.0 1.2 0.9 11.4 2.8 69.6 125.0 0.0 1.1 0.1 25.5 52.8 1.6 10.4 71.9 5.8 70.5 19.9 7.4 10.3 75.4 0.2 4.8 111.1 107.7 9.5 0.8 69.3 0.2 0.0 0.0 9.1 29.0 20.3 0.6 1.9 3.2 0.3 2.6 1.8 346.6 1.0 0.0 0.0 6.0 13.8 49.8 19.3 0.0 0.3 13.9 6.2 0.7 53.2 0.1 0.0 1.4 5.7 3.0 1.2 39.4 1.4 0.4 1.3 0.5 53.9 45.4 MORF4L1 "Eaf3, HsT17725, MEAF3, MORFRG15, MRG15" ENSG00000185787 "Mortality factor 4 like 1" Q9UBU8 15 78810487-78898139 "Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Growth regulation, Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042360, HPA062010" Approved Supported "Nuclear speckles" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 23: Testis - Cell cycle regulation" "Cluster 12: NES - Nervous system development" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" "HPA042360: AB_10794275, HPA062010: AB_2684655" "unprognostic (5.36e-2)" "unprognostic (4.30e-1)" "unprognostic (3.68e-1)" "unprognostic (9.69e-2)" "unprognostic (1.27e-1)" "unprognostic (1.83e-3)" "unprognostic (3.61e-3)" "unprognostic (8.61e-3)" "unprognostic (3.15e-1)" "unprognostic (3.58e-2)" "unprognostic (6.96e-2)" "unprognostic (3.69e-1)" "unprognostic (5.77e-2)" "unprognostic (1.17e-1)" "unprognostic (2.12e-1)" "unprognostic (3.92e-2)" "unprognostic (2.60e-3)" 272.8 306.3 183.9 237.6 193.6 427.6 241.5 197.6 285.5 283.8 188.9 270.1 169.4 305.1 213.0 201.1 257.9 256.5 396.6 187.9 240.5 332.2 258.9 243.4 251.8 232.8 221.6 318.2 165.5 263.6 175.1 300.9 223.4 228.7 225.7 265.5 195.9 282.7 559.3 140.5 187.4 331.5 205.4 217.4 186.9 588.7 220.1 297.6 270.2 425.2 279.6 266.2 184.3 227.9 362.0 480.3 863.5 355.4 603.2 620.4 453.2 644.3 636.0 570.7 554.0 436.9 532.7 446.7 517.2 649.1 376.0 442.1 1054.3 432.8 534.3 446.0 420.3 493.5 483.5 406.5 617.9 410.4 424.3 436.7 482.5 323.1 447.6 550.1 689.1 309.7 526.3 398.2 659.2 335.3 392.9 301.6 930.7 472.9 208.5 431.8 673.0 431.0 459.2 488.1 443.6 457.7 578.1 367.2 825.7 871.1 441.7 533.9 543.1 667.2 471.6 359.0 549.6 256.4 770.6 499.2 412.3 647.4 501.4 118.5 195.0 197.5 123.0 188.4 149.4 172.7 176.9 141.6 225.5 163.7 241.9 174.2 154.9 145.1 155.8 214.4 214.2 318.6 183.9 193.6 197.6 285.5 187.9 240.5 232.8 221.6 223.4 205.4 220.1 227.9 374.2 301.3 249.0 38.2 300.0 418.1 624.1 724.2 256.6 104.5 236.1 198.9 372.2 286.0 512.3 290.6 62.6 611.9 309.4 173.4 686.7 545.5 740.6 377.8 352.6 391.1 275.2 298.0 69.6 312.8 815.0 468.2 153.4 282.5 465.8 179.5 372.3 328.6 379.1 200.2 68.5 263.6 451.6 310.9 601.3 504.6 389.5 325.7 501.6 52.5 450.8 322.0 306.9 40.2 80.0 407.4 185.5 464.9 232.0 489.8 178.6 805.1 582.5 97.5 315.5 368.3 500.6 1322.3 467.9 185.3 370.4 663.0 338.2 279.9 199.0 597.1 MRTFB "FLJ31823, MKL2, MRTF-B" ENSG00000186260 "Myocardin related transcription factor B" Q9ULH7 16 14071319-14266773 "Disease related genes, Predicted intracellular proteins" "Differentiation, Myogenesis, Transcription, Transcription regulation" "Activator, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 43.9;Cardiomyocytes: 26.9;Cytotrophoblasts: 9.9;Endothelial cells: 9.6;Extravillous trophoblasts: 10.0;Smooth muscle cells: 14.9;Syncytiotrophoblasts: 10.4" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 170 "amygdala: 9.4;basal ganglia: 15.1;cerebral cortex: 21.4;hippocampal formation: 21.7" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011286 Enhanced Supported "Nuclear speckles" NA NA "Cluster 30: Non-specific - Translation" "Cluster 46: Fibroblasts - ECM organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nuclear speckles" "HPA011286: AB_1853973" "unprognostic (2.00e-1)" "unprognostic (5.28e-1)" "unprognostic (1.30e-2)" "unprognostic (3.62e-1)" "unprognostic (7.16e-2)" "unprognostic (7.14e-3)" "unprognostic (1.21e-1)" "unprognostic (1.37e-1)" "unprognostic (1.41e-1)" "unprognostic (2.38e-1)" "unprognostic (3.19e-1)" "unprognostic (2.32e-1)" "prognostic favorable (6.20e-4)" "unprognostic (5.22e-2)" "unprognostic (3.55e-1)" "unprognostic (2.47e-2)" "unprognostic (5.96e-2)" 21.4 7.3 9.4 8.6 15.1 3.8 18.3 0.0 21.4 19.0 0.0 9.9 9.7 14.9 9.1 14.5 14.0 13.3 11.8 21.7 0.0 8.4 5.9 13.2 7.6 0.0 0.0 7.1 12.1 22.2 4.9 21.7 0.0 15.5 10.8 8.6 11.6 15.2 11.9 16.6 7.9 15.6 0.0 5.1 10.1 17.5 0.0 10.3 16.9 14.5 8.1 11.3 12.2 0.0 17.6 17.8 17.8 13.2 5.9 11.0 8.0 4.9 13.3 7.4 10.6 7.7 16.4 9.4 12.4 8.4 9.3 13.8 12.9 14.4 13.5 23.1 7.0 6.0 13.6 13.3 8.2 4.2 5.4 8.4 14.6 12.8 8.3 7.8 14.7 12.2 7.9 9.7 5.6 15.1 13.4 2.8 6.0 4.7 4.8 20.5 13.7 8.1 7.3 17.3 6.2 10.8 23.9 10.2 4.9 8.2 18.0 3.5 9.4 15.3 14.9 4.4 6.4 6.6 8.8 8.4 16.6 7.1 11.7 0.2 0.5 0.0 1.1 0.7 1.7 3.7 1.9 0.9 0.7 1.5 2.4 1.3 0.3 1.1 0.8 1.7 0.9 0.6 9.4 15.1 0.0 21.4 21.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.9 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.9 0.0 0.0 0.0 0.0 9.9 1.5 0.0 0.0 0.0 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 10.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.9 0.0 0.0 0.0 0.0 10.4 0.4 0.0 0.0 0.0 MSX2 "CRS2, FPP, HOX8, MSH, PFM, PFM1" ENSG00000120149 "Msh homeobox 2" P35548 5 174724582-174730896 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Osteogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 25.8;placenta: 33.6;urinary bladder: 17.5" "Group enriched" "Detected in many" 6 "Cytotrophoblasts: 162.6;Endometrial ciliated cells: 65.7;Glandular and luminal cells: 62.2;Syncytiotrophoblasts: 233.8" "Cancer enhanced" "Detected in many" "endometrial cancer: 18.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "BEWO: 322.0" "Region enriched" "Detected in some" 5 "cerebellum: 6.2" "Low region specificity" "Detected in many" HPA005652 Uncertain Supported "Nuclear speckles" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nuclear speckles" "HPA005652: AB_1079418" "unprognostic (1.29e-1)" "unprognostic (1.08e-1)" "unprognostic (1.84e-1)" "prognostic favorable (8.43e-5)" "unprognostic (2.50e-2)" "unprognostic (1.22e-2)" "unprognostic (3.13e-1)" "prognostic unfavorable (6.93e-4)" "unprognostic (2.08e-2)" "unprognostic (1.60e-1)" "unprognostic (2.51e-2)" "unprognostic (7.26e-2)" "unprognostic (1.36e-4)" "unprognostic (7.64e-3)" "unprognostic (5.06e-2)" "unprognostic (2.12e-6)" "unprognostic (1.43e-2)" 2.1 0.3 0.7 0.5 1.0 0.0 8.1 4.3 1.1 2.7 1.1 0.9 0.3 6.8 0.0 0.6 0.9 0.9 1.6 1.2 1.4 0.3 0.0 0.8 0.1 7.8 1.3 0.2 0.4 25.8 0.3 33.6 4.1 2.5 0.1 0.0 0.8 0.8 1.9 6.9 0.8 1.4 5.4 0.8 2.8 5.6 1.3 0.1 0.7 1.8 0.1 17.5 1.8 5.4 0.4 4.0 1.1 3.2 0.0 0.0 322.0 2.2 3.6 0.7 0.1 56.6 23.0 0.0 8.6 0.2 19.6 6.2 17.6 6.4 0.2 0.0 10.7 0.0 1.4 0.0 2.4 0.0 3.0 3.7 4.5 3.1 3.5 0.0 0.0 0.0 0.0 0.0 5.0 27.7 0.0 0.4 2.5 38.3 8.5 0.0 8.8 0.1 4.0 35.3 0.0 2.5 0.0 43.0 2.9 69.6 25.7 0.2 0.0 1.1 5.5 17.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.0 4.3 1.1 1.2 1.4 7.8 1.3 4.1 5.4 1.3 5.4 1.5 0.0 0.0 2.3 0.0 9.6 2.4 0.1 3.4 0.2 15.8 18.9 1.7 0.0 0.1 0.0 0.0 162.6 0.2 0.3 0.0 0.6 0.2 65.7 4.9 0.7 0.0 0.0 0.0 0.0 13.9 5.3 5.1 62.2 4.5 0.1 0.4 0.0 11.3 0.0 0.0 1.9 0.0 0.6 2.9 0.6 0.0 1.0 1.8 0.0 0.0 1.6 0.0 0.0 0.0 1.0 0.0 0.0 0.1 2.3 1.9 0.1 0.1 0.0 0.0 8.9 4.8 1.4 4.5 2.0 11.4 233.8 1.0 0.6 1.2 9.8 NCAPG2 "CAP-G2, FLJ20311, hCAP-G2, LUZP5, MTB" ENSG00000146918 "Non-SMC condensin II complex subunit G2" Q86XI2 7 158631169-158704804 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 24.4;lymphoid tissue: 27.9" "Cell type enhanced" "Detected in many" "Spermatocytes: 48.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026631, HPA049637" Approved Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear speckles" "HPA026631: AB_1845983, HPA049637: " "unprognostic (2.73e-2)" "unprognostic (1.77e-1)" "unprognostic (6.81e-2)" "prognostic unfavorable (7.94e-4)" "unprognostic (1.66e-1)" "prognostic favorable (1.91e-4)" "prognostic unfavorable (3.00e-5)" "unprognostic (5.33e-3)" "prognostic unfavorable (3.21e-4)" "unprognostic (7.79e-2)" "prognostic unfavorable (8.50e-4)" "unprognostic (5.19e-2)" "prognostic unfavorable (4.06e-5)" "unprognostic (2.58e-3)" "unprognostic (1.28e-1)" "unprognostic (8.21e-2)" "unprognostic (7.37e-2)" 3.7 2.5 2.0 8.8 2.2 24.4 5.4 2.5 2.1 4.0 1.3 6.9 4.4 4.3 2.1 6.9 3.0 2.9 2.9 2.2 2.1 2.6 4.1 3.1 12.4 2.0 1.7 3.1 2.2 4.6 3.5 5.9 2.1 2.8 7.6 2.8 3.5 2.8 3.4 6.8 5.8 4.8 1.6 4.6 5.6 14.8 1.8 27.9 3.2 4.1 13.8 4.0 3.9 2.4 103.9 53.7 64.1 41.8 9.5 15.4 25.3 74.3 47.4 89.0 99.0 48.5 52.0 64.0 45.0 30.3 95.1 51.7 53.7 33.8 117.2 68.4 40.4 57.2 64.8 38.8 4.2 72.2 62.3 6.8 3.7 73.1 21.0 16.2 50.4 72.9 71.9 91.6 82.8 111.4 119.2 48.8 63.7 58.8 43.3 69.7 67.8 60.6 22.6 45.9 69.6 54.5 91.6 35.0 20.2 40.4 31.4 46.5 25.9 60.6 45.9 166.2 120.6 61.3 48.2 77.2 64.6 89.6 118.5 5.9 0.9 1.1 5.2 1.2 7.5 1.6 5.2 3.6 2.3 1.0 1.6 1.8 0.7 5.2 5.1 1.1 7.2 2.2 2.0 2.2 2.5 2.1 2.2 2.1 2.0 1.7 2.1 1.6 1.8 2.4 3.6 6.4 1.5 3.9 4.1 4.0 2.1 2.8 1.8 3.9 3.7 3.3 4.8 2.8 4.6 1.8 0.0 6.7 5.1 3.4 0.0 2.3 15.1 4.0 4.6 4.3 0.0 19.6 10.7 3.3 10.4 4.5 4.1 5.9 1.3 12.6 2.9 2.6 7.3 8.4 7.2 2.9 2.0 3.8 5.2 7.2 2.8 4.4 1.8 3.7 2.7 2.1 2.1 10.1 10.7 2.3 0.4 4.1 11.0 1.1 0.3 1.3 6.0 2.8 6.6 4.3 5.7 48.2 18.5 6.1 2.0 2.6 4.9 5.0 5.7 3.0 NFATC4 NFAT3 ENSG00000100968 "Nuclear factor of activated T cells 4" Q14934 14 24365673-24379604 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 58.8;Endometrial stromal cells: 28.3;Fibroblasts: 22.8;Sertoli cells: 26.3;Smooth muscle cells: 27.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 36.8;BJ hTERT+: 49.5;hTERT-RPE1: 42.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA031641, CAB032859, HPA076526" Uncertain Supported "Nuclear speckles,Cytosol" No No "Cluster 72: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nuclear speckles, Cytosol" "CAB032859: AB_1128521, HPA031641: AB_10600826, HPA076526: AB_2686805" "unprognostic (3.51e-1)" "unprognostic (5.61e-2)" "prognostic unfavorable (5.84e-4)" "unprognostic (8.08e-2)" "unprognostic (1.67e-1)" "unprognostic (6.57e-2)" "unprognostic (3.24e-2)" "unprognostic (1.15e-1)" "unprognostic (1.27e-1)" "unprognostic (4.18e-2)" "unprognostic (1.39e-1)" "unprognostic (9.11e-2)" "prognostic unfavorable (1.81e-6)" "unprognostic (1.47e-2)" "unprognostic (1.07e-1)" "unprognostic (1.35e-1)" "unprognostic (4.19e-2)" 48.4 54.9 9.1 6.0 9.4 0.6 47.2 8.6 10.5 126.0 9.0 71.9 4.5 82.1 13.7 22.2 82.6 17.8 30.2 9.0 9.3 35.5 5.6 30.2 4.8 10.3 9.4 142.7 13.8 9.0 37.9 18.2 8.8 51.5 5.0 2.8 20.5 16.2 9.0 25.0 29.9 18.8 8.2 17.7 35.5 42.7 9.7 1.7 50.4 2.5 3.6 66.2 65.9 8.5 0.0 0.1 17.8 0.0 25.4 36.8 0.1 17.3 49.5 23.0 20.0 0.0 14.6 14.9 0.5 25.0 1.6 0.0 7.1 0.3 13.9 0.0 0.6 11.3 20.6 0.0 12.3 0.0 0.0 26.8 0.3 13.9 0.1 42.5 18.2 4.7 3.7 0.0 4.5 0.8 0.0 1.7 2.3 1.0 0.1 1.1 1.6 2.0 0.0 0.2 2.9 11.9 0.0 3.3 5.7 8.7 10.3 4.5 10.3 21.3 4.4 20.5 0.0 10.4 1.6 11.0 4.4 0.0 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 9.4 8.6 10.5 9.0 9.3 10.3 9.4 8.8 8.2 9.7 8.5 4.1 3.2 8.1 58.8 1.1 4.5 0.9 1.9 0.6 1.3 3.3 2.8 7.8 0.0 4.8 0.0 0.0 0.6 0.0 0.8 0.0 2.8 4.4 2.5 28.3 4.6 7.7 0.0 0.1 0.2 0.6 22.8 3.6 6.4 0.0 4.1 1.4 0.2 0.6 0.0 0.2 3.4 10.2 0.0 6.8 6.5 17.4 0.4 7.2 13.1 0.0 7.6 0.0 1.0 0.2 0.6 0.3 7.5 0.2 0.8 0.4 0.2 2.1 1.5 26.3 4.3 27.1 12.5 2.9 1.0 3.4 0.5 0.9 6.0 1.6 2.3 NFKBIZ "FLJ34463, INAP, MAIL" ENSG00000144802 "NFKB inhibitor zeta" Q9BYH8 3 101827991-101861022 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "bone marrow: 406.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 33.9" "Group enriched" "Detected in many" 5 "granulocytes: 24.7;monocytes: 33.9" "Cell line enhanced" "Detected in many" "BJ hTERT+: 72.1;RPTEC TERT1: 71.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA010547, HPA075363" Enhanced Supported "Nuclear speckles,Cytoplasmic bodies" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 41: Macrophages - Immune response" "Nuclear speckles" "Cytoplasmic bodies" "HPA010547: AB_1854442, HPA075363: AB_2686745" "unprognostic (2.20e-2)" "unprognostic (1.11e-2)" "unprognostic (6.76e-2)" "unprognostic (1.91e-1)" "unprognostic (1.54e-2)" "unprognostic (1.68e-2)" "unprognostic (1.62e-2)" "unprognostic (1.62e-1)" "unprognostic (9.22e-2)" "unprognostic (5.96e-2)" "unprognostic (1.40e-1)" "unprognostic (8.82e-2)" "prognostic unfavorable (4.30e-8)" "unprognostic (2.69e-1)" "unprognostic (8.90e-2)" "unprognostic (3.30e-1)" "unprognostic (8.52e-3)" 57.5 12.0 2.8 44.4 5.2 406.0 31.7 4.7 6.0 13.4 19.1 24.5 52.6 36.3 3.7 26.9 64.8 51.3 23.6 3.4 4.8 29.2 52.4 48.2 27.2 6.7 4.2 19.1 27.0 3.6 12.5 22.3 5.5 26.6 30.6 8.0 80.8 7.4 4.6 45.7 23.2 54.6 6.2 26.9 30.5 3.7 6.8 18.8 24.7 10.2 22.7 71.3 18.3 5.0 6.5 5.2 3.5 4.4 9.7 16.7 5.3 26.2 72.1 11.3 10.7 6.3 7.8 12.2 32.4 7.2 34.8 20.5 2.5 11.4 29.2 35.9 2.3 11.7 10.2 3.4 14.7 0.8 0.7 11.6 17.3 30.5 13.7 27.8 8.4 0.3 2.0 24.6 16.2 8.1 0.2 6.9 6.0 2.3 15.3 1.5 15.7 1.5 71.0 42.7 1.5 1.9 4.4 5.3 29.6 7.4 6.3 4.8 10.6 18.1 18.0 6.9 8.6 20.4 7.8 8.1 32.9 2.2 2.5 11.7 5.9 1.7 1.4 13.1 1.7 2.9 2.1 1.6 3.8 4.6 6.0 4.2 24.7 0.8 33.9 6.0 1.3 2.3 2.8 5.2 4.7 6.0 3.4 4.8 6.7 4.2 5.5 6.2 6.8 5.0 199.5 86.6 266.6 10.7 91.3 281.7 61.2 123.0 103.0 9.0 108.7 105.8 20.6 84.4 143.0 66.2 2.1 19.3 98.6 157.8 0.0 213.0 4.6 116.1 221.4 135.3 73.6 21.0 23.7 132.1 41.0 214.2 277.8 291.9 381.8 17.9 82.1 65.2 56.5 10.1 20.2 69.7 59.0 150.6 291.5 1.3 20.2 318.4 71.2 16.9 79.0 25.7 12.3 17.1 79.3 127.6 115.8 0.7 128.5 88.8 91.2 5.6 117.3 8.9 19.7 218.4 131.1 0.6 2.6 136.4 251.7 25.6 134.0 19.2 111.7 70.5 NONO "NMT55, NRB54, P54, P54NRB, PPP1R114" ENSG00000147140 "Non-POU domain containing octamer binding" Q15233 X 71254814-71301522 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, DNA damage, DNA recombination, DNA repair, Immunity, Innate immunity, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor, RNA-binding" "Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022069, HPA054094, HPA054559" Enhanced Enhanced "Nucleoplasm,Nucleoli fibrillar center,Nuclear speckles" NA NA 450000 "Cluster 44: Non-specific - Transcription" "Cluster 63: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Nucleoli fibrillar center, Nuclear speckles" "CAB022069: , HPA054094: AB_2682376, HPA054559: AB_2682522" "unprognostic (2.39e-3)" "unprognostic (2.22e-2)" "unprognostic (2.64e-1)" "prognostic unfavorable (9.29e-4)" "unprognostic (8.87e-2)" "unprognostic (5.54e-2)" "unprognostic (1.02e-3)" "unprognostic (9.34e-2)" "unprognostic (2.32e-2)" "unprognostic (1.41e-2)" "unprognostic (3.12e-1)" "unprognostic (2.07e-1)" "unprognostic (7.29e-3)" "unprognostic (6.79e-2)" "unprognostic (5.73e-3)" "unprognostic (2.76e-2)" "unprognostic (3.04e-2)" 106.4 147.2 58.6 96.4 57.7 115.3 109.2 71.5 64.9 116.8 64.4 101.3 86.2 130.2 107.9 111.9 115.4 100.7 81.2 55.3 69.9 103.3 121.5 103.2 136.5 60.3 61.5 197.9 164.8 114.8 97.1 99.1 60.5 97.0 101.2 70.2 106.8 89.6 99.1 112.2 102.0 113.5 59.2 109.5 114.3 55.2 68.5 255.5 116.0 86.1 165.2 116.8 102.6 61.0 421.2 539.7 595.3 344.4 251.2 238.5 345.3 330.9 319.2 459.3 388.5 413.4 312.9 481.4 379.9 320.5 309.7 310.5 949.5 299.4 488.1 383.9 605.7 394.8 498.4 398.0 212.3 547.7 338.7 272.0 206.0 473.1 305.7 370.5 382.0 342.1 535.3 509.0 406.2 413.9 756.0 466.8 771.3 433.9 365.2 660.0 657.3 414.0 345.9 426.1 431.7 519.4 467.8 299.1 392.5 354.9 271.4 354.0 343.9 268.0 438.6 402.9 400.1 297.3 503.2 516.0 216.8 627.1 433.8 107.5 117.3 91.1 107.9 120.0 119.9 107.4 107.9 106.4 118.7 107.2 115.1 115.6 50.8 119.6 140.7 101.1 128.0 178.1 58.6 57.7 71.5 64.9 55.3 69.9 60.3 61.5 60.5 59.2 68.5 61.0 72.9 76.9 81.1 16.3 97.2 126.3 99.9 105.8 116.7 62.3 111.4 83.6 63.5 90.1 99.8 44.1 41.7 132.3 103.6 52.0 56.7 147.8 11.8 81.6 137.8 95.4 139.8 144.6 16.2 111.4 179.9 93.9 71.4 104.8 88.0 135.9 83.9 128.3 112.6 53.8 20.7 105.6 95.6 153.2 107.7 15.9 106.6 95.0 56.9 13.1 132.0 84.8 96.8 19.6 22.8 110.7 75.4 127.9 115.2 94.9 89.0 121.0 71.1 50.3 65.7 78.7 127.8 45.7 66.5 137.3 122.3 130.1 108.5 163.7 117.2 103.0 NR2F6 "EAR-2, EAR2, ERBAL2" ENSG00000160113 "Nuclear receptor subfamily 2 group F member 6" P10588 19 17231883-17245919 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 104.0" "Cell type enhanced" "Detected in all" "Distal enterocytes: 206.0;Hepatocytes: 148.4;Horizontal cells: 151.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BEWO: 187.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB079917 Supported "Nuclear speckles,Cytosol" NA Yes "Cluster 15: NK-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear speckles" Cytosol "CAB079917: AB_2635238" "unprognostic (1.48e-1)" "unprognostic (1.30e-1)" "unprognostic (2.17e-1)" "prognostic unfavorable (4.36e-4)" "unprognostic (1.08e-1)" "unprognostic (1.12e-1)" "unprognostic (3.07e-1)" "unprognostic (3.67e-1)" "unprognostic (7.20e-2)" "unprognostic (1.02e-2)" "unprognostic (2.39e-1)" "unprognostic (6.62e-2)" "unprognostic (9.68e-2)" "unprognostic (1.31e-1)" "unprognostic (2.29e-2)" "unprognostic (7.28e-3)" "unprognostic (1.37e-3)" 17.0 21.8 19.3 5.0 16.9 1.2 17.7 15.8 22.8 18.8 23.8 39.4 31.2 19.8 14.3 47.4 19.1 2.9 39.0 16.8 20.2 32.8 104.0 17.5 1.7 23.9 21.4 12.1 44.6 10.4 22.0 13.1 18.6 25.3 9.3 6.6 28.0 9.8 27.9 23.9 25.4 4.5 17.5 9.9 38.6 14.3 20.4 1.8 21.6 9.9 2.7 25.5 22.2 15.6 65.0 38.1 20.3 37.2 7.9 8.8 187.2 35.7 12.9 15.2 13.1 26.1 55.5 15.2 108.8 16.0 8.9 31.9 15.6 20.5 6.7 20.4 90.0 13.9 24.4 47.3 17.3 6.7 18.8 11.6 23.2 7.0 11.3 15.9 9.5 6.8 33.3 3.7 6.7 34.7 5.9 24.7 55.8 48.1 58.5 11.6 12.7 13.2 21.2 41.3 16.3 46.7 19.9 68.7 43.1 19.6 38.2 21.1 15.8 10.7 26.1 20.6 28.8 21.0 7.9 10.9 13.1 9.9 13.4 0.0 0.6 1.1 1.7 0.0 1.4 0.3 2.3 1.5 1.1 2.3 3.8 1.3 0.1 4.6 0.1 0.5 2.4 0.8 19.3 16.9 15.8 22.8 16.8 20.2 23.9 21.4 18.6 17.5 20.4 15.6 21.2 9.6 22.9 6.8 4.7 10.6 14.1 12.8 11.4 71.9 65.9 54.7 36.4 34.3 20.8 25.8 77.2 65.4 3.7 206.0 29.4 23.2 13.3 51.7 32.5 20.8 46.0 4.4 7.2 47.8 65.3 17.6 47.4 60.0 1.3 26.1 15.0 148.4 16.3 151.4 7.6 80.2 24.4 4.7 4.6 6.0 17.7 5.2 10.6 8.4 2.4 45.7 1.0 6.6 5.8 50.4 78.5 18.8 1.2 23.2 72.3 30.2 25.9 54.3 6.6 17.3 24.5 1.6 9.0 24.3 10.5 79.8 4.2 44.3 75.3 18.2 NR4A2 "HZF-3, NOT, NURR1, RNR1, TINUR" ENSG00000153234 "Nuclear receptor subfamily 4 group A member 2" P43354 2 156324437-156342348 "Cancer-related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 129.3;bone marrow: 130.8;ovary: 129.2" "Cell type enhanced" "Detected in many" "B-cells: 511.7;dendritic cells: 410.4;Langerhans cells: 782.3;Macrophages: 577.5;T-cells: 465.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 6.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HeLa: 16.0;HMC-1: 10.9;SK-MEL-30: 8.1;U-266/70: 14.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000543, CAB010481" Uncertain Supported "Nuclear speckles" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 20: HeLa - Mitochondria" "Cluster 41: Macrophages - Immune response" "Nuclear speckles" "CAB010481: AB_2298676, HPA000543: AB_1854631" "unprognostic (4.26e-2)" "unprognostic (2.14e-1)" "unprognostic (3.42e-2)" "unprognostic (4.10e-2)" "unprognostic (3.04e-2)" "unprognostic (5.26e-2)" "unprognostic (2.30e-1)" "unprognostic (6.14e-2)" "unprognostic (8.63e-2)" "unprognostic (3.88e-2)" "unprognostic (1.60e-2)" "unprognostic (2.89e-1)" "unprognostic (2.39e-2)" "unprognostic (3.58e-2)" "unprognostic (3.43e-1)" "unprognostic (9.29e-3)" "unprognostic (1.11e-1)" 40.0 129.3 4.3 24.5 44.1 130.8 15.6 36.2 8.8 18.3 5.9 9.5 2.9 15.0 1.7 11.4 28.2 32.7 36.6 15.1 3.6 19.2 20.2 18.8 6.3 3.2 9.2 129.2 9.2 8.8 54.0 5.2 2.8 25.6 18.7 5.3 19.2 15.5 11.6 12.8 7.8 14.5 0.9 4.6 19.9 5.6 2.5 9.7 15.2 7.8 1.4 50.9 14.0 6.4 0.9 1.3 0.5 1.8 3.2 0.7 0.9 1.1 5.5 0.4 1.3 0.0 3.3 0.0 1.2 0.4 0.4 1.6 2.6 0.7 0.4 1.3 1.4 1.0 16.0 0.0 0.6 0.7 10.9 0.6 1.2 0.4 0.4 2.1 0.3 0.0 1.6 1.0 1.1 1.9 0.0 0.8 2.1 1.5 0.8 0.2 0.7 3.3 0.6 0.8 2.7 0.1 2.6 4.1 8.1 0.3 0.2 1.0 0.7 2.9 0.8 0.7 0.4 14.2 1.8 0.0 5.3 1.0 7.0 1.9 1.7 2.4 1.0 0.3 0.5 0.4 0.3 0.5 1.9 0.3 0.5 0.2 6.5 0.0 0.7 0.0 0.4 0.5 4.3 44.1 36.2 8.8 15.1 3.6 3.2 9.2 2.8 0.9 2.5 6.4 70.7 25.6 124.7 7.8 511.7 218.6 25.8 87.5 298.7 11.8 120.8 160.1 11.9 17.2 58.3 71.7 50.1 4.7 410.4 35.0 0.0 13.1 36.7 209.6 33.9 111.9 206.4 12.0 5.8 9.1 6.5 164.9 103.9 349.7 349.3 4.3 45.0 6.8 125.1 0.0 0.8 95.4 42.7 161.1 782.3 37.2 4.1 577.5 241.9 5.6 7.9 1.6 3.1 4.0 2.3 11.7 41.9 0.7 203.5 49.1 25.9 0.4 54.6 33.4 13.1 63.0 169.8 1.8 3.3 230.2 213.7 9.9 465.1 34.4 57.5 29.5 NSL1 "C1orf48, DC8, DKFZP566O1646, MIS14" ENSG00000117697 "NSL1 component of MIS12 kinetochore complex" Q96IY1 1 212726153-212791782 "Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA045761, HPA053721" Enhanced Supported "Nuclear speckles" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "HPA045761: AB_2679444, HPA053721: AB_2682240" "unprognostic (1.47e-1)" "unprognostic (1.67e-1)" "unprognostic (8.08e-2)" "unprognostic (2.67e-2)" "unprognostic (2.58e-2)" "unprognostic (1.78e-2)" "unprognostic (8.22e-3)" "unprognostic (3.55e-1)" "unprognostic (4.78e-2)" "unprognostic (6.09e-3)" "unprognostic (3.44e-3)" "unprognostic (1.58e-1)" "unprognostic (3.10e-3)" "unprognostic (2.59e-1)" "unprognostic (1.04e-2)" "unprognostic (1.67e-1)" "unprognostic (6.66e-2)" 16.7 14.5 13.8 19.4 16.9 19.1 11.2 17.1 17.5 12.8 15.0 13.3 17.5 14.5 8.0 15.3 13.9 15.0 24.9 13.4 14.9 16.0 19.3 12.5 27.0 18.0 14.9 16.8 12.5 13.9 11.0 17.6 17.5 12.8 10.1 12.6 13.9 10.0 22.5 8.8 17.5 13.1 17.3 19.4 11.7 13.5 14.8 22.7 15.0 15.6 16.7 13.6 10.1 21.3 39.7 44.3 45.0 43.3 18.9 19.5 59.4 32.5 22.1 38.7 33.2 37.3 42.2 55.6 29.4 18.7 21.6 28.4 35.6 29.9 20.1 102.9 33.6 37.0 31.2 61.8 21.7 62.5 34.9 20.2 14.6 39.6 19.8 17.8 28.8 62.9 83.0 45.7 24.6 23.1 80.6 24.6 82.9 20.6 32.8 69.2 68.1 61.5 31.3 19.8 41.1 57.0 46.0 22.3 55.7 33.3 65.6 44.9 33.3 39.4 34.1 36.4 54.5 26.4 76.3 73.8 33.7 42.2 50.7 21.8 49.3 63.1 35.9 62.3 43.0 59.0 38.8 39.2 55.6 47.4 46.7 41.9 49.6 45.3 64.3 53.8 51.2 60.7 13.8 16.9 17.1 17.5 13.4 14.9 18.0 14.9 17.5 17.3 14.8 21.3 39.4 16.0 20.7 25.5 43.5 14.8 21.2 51.4 31.3 34.1 22.8 26.8 22.4 31.5 28.1 18.4 14.6 64.0 40.9 14.7 43.0 32.2 29.2 19.9 29.0 32.0 21.7 50.7 50.2 21.1 62.2 28.9 13.3 15.1 15.2 31.6 29.6 27.9 61.6 33.7 50.1 14.1 30.5 68.2 28.5 15.2 34.8 44.6 19.6 33.7 56.0 37.1 35.0 36.2 68.9 22.7 15.9 32.7 26.7 10.5 32.5 58.5 25.6 32.7 59.2 30.2 32.6 48.7 65.5 22.7 16.2 20.9 36.6 27.0 18.5 10.3 OIP5 "CT86, hMIS18beta, MIS18B" ENSG00000104147 "Opa interacting protein 5" O43482 15 41309273-41332591 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.3;skeletal muscle: 10.3;testis: 20.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 45.9;Extravillous trophoblasts: 24.0;Spermatocytes: 110.6;Spermatogonia: 56.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA052271, HPA059602" Enhanced Supported "Nuclear speckles,Vesicles" NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear speckles" Vesicles "HPA052271: AB_2681780, HPA059602: AB_2684079" "unprognostic (5.17e-2)" "unprognostic (7.26e-2)" "unprognostic (3.07e-1)" "unprognostic (1.59e-2)" "unprognostic (6.94e-2)" "unprognostic (6.58e-2)" "prognostic unfavorable (1.79e-4)" "prognostic unfavorable (2.26e-4)" "unprognostic (2.71e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (9.34e-5)" "unprognostic (5.51e-2)" "unprognostic (0.00e+0)" "unprognostic (3.84e-2)" "unprognostic (2.02e-1)" "unprognostic (5.75e-2)" "unprognostic (2.86e-2)" 0.6 1.7 0.1 3.3 0.2 10.3 1.2 1.2 0.4 0.9 0.2 4.1 3.5 0.8 0.3 3.8 0.4 0.6 1.5 0.2 0.2 0.3 1.2 0.5 5.8 0.2 0.4 1.5 0.3 0.1 0.1 2.3 0.4 0.5 3.9 0.7 0.8 0.6 10.3 3.3 3.9 1.1 0.1 1.7 1.5 20.9 0.2 9.1 0.4 0.8 5.2 0.7 1.3 0.5 33.7 17.8 34.3 24.9 1.7 2.1 32.4 20.0 9.3 24.5 26.1 31.8 16.2 19.8 17.0 7.7 37.8 51.0 35.7 16.1 19.2 42.4 40.1 42.4 49.8 33.6 0.4 46.5 22.1 0.7 3.2 13.8 14.5 5.2 21.1 40.8 59.4 37.3 16.5 16.3 27.1 34.8 30.9 50.4 37.9 32.9 28.4 30.5 11.1 15.4 53.7 17.5 33.7 34.3 9.6 13.7 33.7 26.3 10.0 24.5 37.3 24.6 36.6 17.0 83.2 71.1 7.1 56.5 35.9 0.0 0.4 0.5 0.2 0.7 0.8 1.0 0.7 0.8 0.7 1.2 1.3 0.8 0.0 1.2 0.4 4.1 3.1 0.8 0.1 0.2 1.2 0.4 0.2 0.2 0.2 0.4 0.4 0.1 0.2 0.5 0.2 0.0 0.5 1.0 2.7 4.1 0.9 3.6 1.2 0.0 1.1 2.2 0.2 0.0 1.8 0.0 0.0 15.0 1.7 2.3 0.0 0.4 12.0 1.9 0.6 0.9 0.0 45.9 2.2 0.4 24.0 1.7 5.1 1.1 1.3 5.2 0.0 0.8 7.5 0.0 2.1 3.0 8.2 2.2 1.8 10.8 0.9 1.2 0.0 0.0 0.6 1.1 2.1 1.5 2.5 0.2 0.5 1.2 10.9 0.4 0.9 0.3 0.0 0.3 6.6 1.0 1.1 110.6 56.8 8.3 2.4 3.8 1.2 2.1 7.6 0.9 PARN DAN ENSG00000140694 "Poly(A)-specific ribonuclease" O95453 16 14435700-14632728 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Nonsense-mediated mRNA decay" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Disease variant, Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006314, CAB011673, HPA012010" Supported Supported "Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "CAB011673: AB_778216, HPA006314: AB_1079567, HPA012010: AB_1854976" "unprognostic (2.54e-1)" "unprognostic (3.43e-2)" "unprognostic (1.55e-1)" "unprognostic (2.23e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (4.64e-4)" "unprognostic (2.99e-3)" "unprognostic (5.07e-2)" "unprognostic (1.32e-1)" "unprognostic (1.94e-1)" "unprognostic (2.16e-3)" "unprognostic (1.75e-1)" "unprognostic (1.52e-1)" "unprognostic (3.25e-2)" "unprognostic (2.46e-1)" "unprognostic (3.10e-3)" "unprognostic (1.09e-2)" 16.6 20.2 10.8 13.9 12.1 9.2 15.9 11.7 11.4 17.2 12.0 19.3 11.8 19.1 24.7 15.6 16.0 13.4 14.8 10.6 14.0 12.7 16.4 14.2 21.2 11.7 11.9 16.4 16.5 21.1 16.3 15.6 11.9 16.1 16.8 7.0 15.3 17.1 16.8 17.9 16.1 18.0 11.3 15.7 16.2 18.1 12.6 21.6 20.6 9.7 23.4 19.3 16.0 13.5 28.0 39.9 17.6 22.9 32.9 33.2 20.3 24.4 32.4 29.8 28.3 21.9 28.7 56.2 63.1 32.3 25.3 30.4 46.7 32.3 41.0 42.9 29.4 28.8 24.2 53.2 35.5 46.0 36.2 32.5 38.5 32.0 43.1 25.5 22.5 32.6 28.5 29.9 32.5 44.9 36.7 33.1 26.0 28.2 16.7 56.2 36.1 57.1 23.1 17.1 18.7 16.9 53.4 29.6 36.3 28.6 31.6 28.0 21.2 31.5 15.8 16.4 26.9 32.5 31.0 63.5 34.6 30.8 35.8 8.9 8.0 15.8 8.6 13.2 7.7 16.0 10.4 12.4 13.6 9.4 14.2 14.4 6.2 15.0 15.6 8.3 19.1 7.1 10.8 12.1 11.7 11.4 10.6 14.0 11.7 11.9 11.9 11.3 12.6 13.5 18.0 32.1 39.1 37.9 26.2 7.1 7.8 9.7 21.6 13.0 13.4 14.0 22.3 7.2 11.8 11.0 8.4 29.2 24.7 13.6 11.7 14.2 14.1 15.2 20.5 15.2 14.9 20.4 48.0 12.9 23.2 19.5 21.9 21.7 2.5 19.2 11.7 15.6 14.8 8.4 48.2 14.3 6.1 14.2 5.8 6.3 21.1 18.2 10.6 54.4 35.8 10.3 52.5 38.2 72.4 15.2 10.6 17.7 23.0 7.1 12.2 10.8 19.2 10.8 19.7 13.1 15.0 70.5 70.5 20.0 8.2 22.4 21.5 20.1 13.4 4.8 PLAG1 ZNF912 ENSG00000181690 "PLAG1 zinc finger" Q6DJT9 8 56160909-56211324 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Horizontal cells: 32.0;Microglial cells: 28.1;Rod photoreceptor cells: 27.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 16.0;ASC TERT1: 20.9;hTERT-HME1: 15.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA072290 Supported "Nucleoplasm,Nuclear speckles,Centrosome,Cytosol" NA NA "Cluster 30: Non-specific - Translation" "Cluster 77: Retina - Visual perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nuclear speckles" "Centrosome, Cytosol" "HPA072290: AB_2686508" "unprognostic (1.89e-2)" "unprognostic (1.93e-2)" "unprognostic (1.22e-3)" "unprognostic (1.63e-4)" "unprognostic (6.81e-2)" "unprognostic (1.07e-1)" "unprognostic (5.63e-3)" "unprognostic (8.56e-2)" "unprognostic (1.18e-1)" "unprognostic (7.99e-2)" "unprognostic (3.42e-2)" "unprognostic (1.97e-1)" "unprognostic (1.32e-3)" "unprognostic (2.83e-2)" "unprognostic (3.94e-1)" "unprognostic (1.21e-2)" "unprognostic (6.14e-2)" 0.7 1.4 0.8 1.0 1.2 0.9 0.9 2.5 1.1 3.0 0.6 0.8 1.4 1.4 4.1 0.7 3.1 0.7 3.1 0.7 1.0 1.3 0.3 1.9 1.8 1.5 1.4 4.9 0.8 1.2 3.8 1.6 1.8 1.3 0.6 7.7 3.0 1.8 0.4 1.4 2.3 0.4 1.2 2.6 1.3 2.4 1.3 2.8 1.3 1.4 2.3 1.3 3.0 2.0 2.0 0.0 11.9 0.1 16.0 20.9 3.7 5.4 6.9 2.5 1.1 0.8 6.2 0.2 5.1 2.9 0.7 0.4 3.4 7.1 2.5 0.2 7.4 8.0 0.8 1.8 3.3 2.5 2.3 14.9 3.9 1.4 15.6 6.9 4.7 5.3 3.4 0.1 5.3 0.1 0.7 4.7 3.4 0.5 1.8 6.1 0.8 4.9 3.2 0.7 0.1 0.0 0.1 0.1 0.4 8.0 0.1 2.4 7.2 3.6 4.6 5.9 1.4 1.8 1.5 2.9 4.1 0.9 1.0 0.6 0.0 0.4 0.1 0.0 0.1 1.3 0.4 0.2 0.0 0.7 1.8 1.8 0.4 0.3 0.2 0.1 0.1 0.4 0.8 1.2 2.5 1.1 0.7 1.0 1.5 1.4 1.8 1.2 1.3 2.0 2.6 6.4 3.2 2.9 13.0 1.0 2.5 6.2 1.8 23.6 1.6 0.6 12.2 4.3 6.7 5.5 25.0 8.3 2.0 1.0 0.0 0.7 6.2 3.0 2.3 3.7 5.4 5.0 16.8 1.3 4.2 4.0 2.6 4.2 1.3 0.4 15.7 0.7 5.8 32.0 12.3 3.6 6.1 2.9 2.2 6.7 15.2 2.8 16.0 28.1 1.2 16.3 4.1 2.0 19.2 1.4 4.1 10.1 6.3 5.0 5.1 0.8 9.1 27.8 0.0 2.4 1.4 9.0 8.8 1.1 0.9 7.1 4.5 0.9 3.6 12.9 PNISR "bA98I9.2, C6orf111, DKFZp564B0769, FLJ14752, SFRS18, SRrp130" ENSG00000132424 "PNN interacting serine and arginine rich protein" Q8TF01 6 99397629-99425331 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038796, HPA075076" Approved Supported "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 51: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "Plasma membrane, Cytosol" "HPA038796: AB_10672652, HPA075076: " "unprognostic (2.95e-1)" "unprognostic (2.29e-1)" "unprognostic (2.11e-1)" "unprognostic (9.72e-3)" "unprognostic (1.68e-2)" "unprognostic (8.55e-3)" "unprognostic (4.41e-2)" "unprognostic (1.58e-3)" "unprognostic (5.82e-2)" "unprognostic (4.32e-3)" "prognostic favorable (5.27e-4)" "unprognostic (1.47e-2)" "prognostic unfavorable (1.41e-4)" "unprognostic (3.43e-2)" "unprognostic (2.59e-1)" "unprognostic (8.89e-2)" "prognostic favorable (1.09e-4)" 68.2 68.8 56.9 52.0 55.4 106.8 75.3 78.4 89.8 103.1 67.5 114.5 51.4 79.7 93.6 51.8 93.2 38.2 84.6 54.3 56.4 67.1 62.2 74.4 78.7 56.7 54.7 123.0 66.0 38.4 112.0 36.4 52.9 91.2 49.4 102.1 76.6 48.1 89.4 64.1 94.1 49.4 49.3 90.6 77.1 39.4 56.9 51.4 114.5 31.2 54.9 81.6 80.3 60.1 26.7 19.5 98.8 72.0 35.3 46.8 45.8 44.1 22.8 25.6 29.9 33.3 49.2 85.8 26.6 25.3 28.7 41.9 49.3 33.3 45.2 75.0 48.8 52.6 105.0 30.6 22.2 73.0 67.9 51.8 50.0 27.4 37.5 95.7 34.2 44.8 59.3 52.5 31.3 25.2 31.8 71.2 55.2 24.5 15.3 62.1 29.6 32.4 47.1 47.1 43.4 51.9 21.7 23.6 35.3 75.4 32.8 58.6 45.0 25.2 28.9 25.7 37.2 35.9 24.3 70.5 37.5 68.3 27.0 12.3 10.8 11.9 12.5 6.4 13.0 19.3 12.0 10.4 5.0 25.8 17.9 16.6 30.0 23.5 7.7 19.6 12.4 3.7 56.9 55.4 78.4 89.8 54.3 56.4 56.7 54.7 52.9 49.3 56.9 60.1 175.8 185.9 237.6 356.2 375.8 195.3 357.3 250.5 165.6 546.2 143.9 192.5 121.2 137.2 215.7 178.4 446.2 158.3 336.4 152.4 74.3 130.8 17.0 132.2 185.7 210.7 247.8 194.4 241.5 104.5 102.1 240.1 100.9 140.5 190.5 344.5 135.7 109.4 99.7 498.0 257.4 129.6 199.4 128.0 236.8 47.9 593.3 152.1 167.2 193.9 261.6 223.6 375.9 270.4 252.6 133.1 176.2 441.2 209.8 293.6 205.8 58.6 179.6 419.9 249.8 288.7 236.3 342.6 181.3 115.5 173.6 180.9 283.8 363.3 151.3 352.4 PNN memA ENSG00000100941 "Pinin, desmosome associated protein" Q9H307 14 39175183-39183220 "Predicted intracellular proteins, Transporters" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, DNA-binding" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001378 Supported Supported "Nuclear speckles" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 18: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "HPA001378: AB_1079648" "unprognostic (9.28e-3)" "unprognostic (5.07e-2)" "unprognostic (5.46e-2)" "unprognostic (3.91e-1)" "unprognostic (7.38e-3)" "unprognostic (7.40e-2)" "prognostic unfavorable (5.79e-4)" "unprognostic (1.65e-2)" "unprognostic (1.67e-3)" "unprognostic (3.75e-2)" "unprognostic (3.70e-2)" "prognostic unfavorable (2.44e-4)" "unprognostic (1.51e-3)" "unprognostic (1.25e-1)" "unprognostic (1.53e-1)" "unprognostic (1.00e-1)" "unprognostic (4.30e-2)" 57.8 60.6 42.7 68.0 46.6 135.9 60.2 50.6 48.1 82.2 77.8 83.1 56.5 81.5 129.5 74.0 77.0 41.8 54.9 42.9 51.4 87.6 124.8 61.4 87.6 47.5 45.1 84.5 78.5 40.8 90.7 53.8 47.2 83.8 63.1 76.0 65.6 48.4 59.9 67.7 90.5 48.0 43.9 103.6 70.7 58.5 47.1 65.6 88.4 27.0 69.5 69.2 73.3 50.9 152.4 72.0 193.2 94.0 45.5 37.4 141.4 116.6 35.4 82.4 81.2 112.3 232.6 229.1 72.7 53.2 69.7 156.4 153.3 85.5 138.5 105.1 109.0 158.6 243.7 246.0 39.1 201.0 107.6 55.8 73.5 80.1 65.1 115.5 57.3 119.0 149.1 128.2 65.8 122.6 145.5 170.3 126.6 76.2 114.3 188.4 137.0 64.2 65.6 219.3 93.8 50.5 126.2 90.5 69.1 133.2 114.4 117.5 92.7 115.9 90.9 52.7 142.2 102.5 87.8 194.0 59.5 167.3 70.6 9.2 13.7 22.0 17.0 11.4 16.1 22.2 12.1 10.9 11.8 25.5 17.2 16.6 27.6 15.4 16.4 22.1 14.2 6.1 42.7 46.6 50.6 48.1 42.9 51.4 47.5 45.1 47.2 43.9 47.1 50.9 105.6 192.3 125.0 40.8 170.5 126.2 244.5 84.4 153.1 203.1 77.5 87.5 63.4 61.5 164.8 60.7 56.3 113.2 230.9 129.3 35.2 89.4 59.0 155.0 178.9 127.9 136.2 121.1 33.1 58.3 100.0 117.1 101.9 289.4 142.5 273.5 69.3 67.8 62.3 153.1 35.6 96.6 71.2 69.3 72.5 53.7 156.3 93.9 49.8 25.3 89.2 138.0 193.6 41.2 54.6 76.7 126.3 151.6 116.7 172.1 82.9 28.9 111.7 172.4 151.2 166.2 161.3 212.8 149.3 145.0 112.0 99.6 170.6 211.8 123.7 245.4 POLI "RAD30B, RAD3OB" ENSG00000101751 "DNA polymerase iota" Q9UNA4 18 54269517-54321266 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, DNA synthesis" "DNA-binding, DNA-directed DNA polymerase, Mutator protein, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 117.4;Spermatocytes: 80.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012000, HPA064696" Enhanced Supported "Nuclear speckles,Cytoplasmic bodies" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" "Cytoplasmic bodies" "HPA012000: AB_1847786, HPA064696: AB_2685325" "unprognostic (1.64e-1)" "unprognostic (5.79e-3)" "unprognostic (9.72e-3)" "unprognostic (4.92e-2)" "unprognostic (3.04e-1)" "unprognostic (4.46e-2)" "unprognostic (1.31e-1)" "unprognostic (1.05e-2)" "unprognostic (4.04e-3)" "unprognostic (2.22e-2)" "unprognostic (2.07e-3)" "unprognostic (1.30e-3)" "unprognostic (1.55e-1)" "unprognostic (4.05e-2)" "unprognostic (1.26e-1)" "unprognostic (1.52e-2)" "unprognostic (6.99e-2)" 21.2 9.2 7.6 7.2 10.6 7.0 18.2 7.4 9.2 13.8 4.8 9.5 7.8 15.0 14.4 7.2 11.3 9.6 10.7 5.7 8.5 14.4 7.5 10.0 9.6 9.5 8.0 16.7 13.4 15.8 11.5 14.8 8.3 14.1 8.6 25.4 8.2 14.6 6.3 7.5 6.6 11.5 8.6 9.4 9.7 38.0 8.5 14.6 31.4 5.6 8.4 9.4 8.7 12.9 12.0 4.3 31.4 19.1 10.3 20.1 10.2 9.7 20.6 10.9 18.0 3.2 11.1 5.6 3.1 14.2 11.1 9.6 7.4 11.1 12.2 13.7 3.7 7.1 5.2 8.3 16.9 11.4 5.5 21.9 16.4 9.5 19.6 24.5 23.4 9.1 4.9 15.6 18.3 9.6 8.2 9.9 10.8 3.0 4.7 5.1 6.4 14.1 12.3 15.9 14.6 14.9 6.9 6.0 10.1 20.2 22.1 5.1 11.3 20.4 5.5 3.1 8.2 12.6 3.0 7.9 14.5 10.0 15.1 4.0 6.3 6.7 4.6 3.5 4.3 5.1 4.8 4.8 6.1 6.5 7.0 4.0 3.9 4.9 3.7 4.8 6.1 3.9 7.6 10.6 7.4 9.2 5.7 8.5 9.5 8.0 8.3 8.6 8.5 12.9 8.7 25.6 16.4 24.5 5.0 2.5 8.0 9.1 10.8 15.3 12.1 10.0 10.5 2.8 9.6 5.5 10.4 33.5 4.7 1.8 9.8 9.0 117.4 14.4 12.3 8.0 6.1 5.0 16.5 6.2 16.6 11.0 9.2 10.3 13.3 13.9 8.9 6.1 9.2 3.3 20.3 4.7 8.2 5.9 2.5 25.4 19.9 6.2 7.2 26.2 8.2 18.7 7.2 28.6 43.5 6.2 2.6 18.0 3.3 4.7 3.7 15.6 20.6 23.6 32.9 13.9 9.6 80.1 31.4 4.9 2.6 27.9 6.4 11.7 4.3 3.1 POLR2D RPB4 ENSG00000144231 "RNA polymerase II subunit D" O15514 2 127843553-127858155 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 74.3" "Cell type enhanced" "Detected in all" "Late spermatids: 170.2;Spermatocytes: 86.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034694, HPA046092" Approved Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Nuclear speckles" "HPA034694: AB_2674284, HPA046092: AB_10963049" "unprognostic (3.57e-2)" "unprognostic (3.76e-2)" "unprognostic (2.59e-1)" "unprognostic (2.54e-2)" "unprognostic (2.77e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (8.91e-4)" "unprognostic (2.51e-1)" "unprognostic (7.95e-3)" "unprognostic (2.64e-3)" "unprognostic (1.97e-1)" "unprognostic (2.51e-1)" "prognostic unfavorable (2.79e-4)" "unprognostic (3.66e-2)" "unprognostic (6.57e-2)" "unprognostic (1.17e-1)" "unprognostic (2.38e-1)" 12.3 10.4 7.2 14.4 9.8 32.4 11.9 9.6 8.3 9.4 7.3 12.0 9.7 10.3 8.0 12.3 10.6 8.4 10.0 7.5 8.7 8.8 19.2 10.2 19.7 8.0 8.9 15.0 14.7 10.4 8.3 15.9 8.3 9.5 14.7 8.1 8.4 9.2 29.3 11.3 9.3 15.0 8.4 12.8 9.4 74.3 8.1 28.3 9.1 27.1 26.9 15.3 8.4 11.0 63.4 40.6 73.9 51.9 26.8 29.2 59.0 59.1 27.9 69.6 61.9 92.0 50.9 97.7 49.6 40.0 39.8 32.7 107.0 51.2 107.3 57.7 58.3 96.6 37.9 85.4 31.4 104.9 51.6 20.8 37.8 93.3 53.2 19.3 46.1 70.4 137.1 84.8 40.4 50.1 105.0 47.5 103.6 65.9 46.4 99.3 77.8 88.0 23.1 42.6 45.7 60.9 39.9 48.9 50.7 54.7 54.6 71.4 47.0 60.1 84.4 34.4 69.0 99.4 173.4 173.0 52.4 51.2 60.5 9.9 22.8 17.3 26.3 31.7 25.0 22.8 21.0 23.2 29.9 20.2 27.6 23.7 7.3 25.8 35.0 19.5 20.6 21.3 7.2 9.8 9.6 8.3 7.5 8.7 8.0 8.9 8.3 8.4 8.1 11.0 10.9 3.2 11.7 2.6 22.0 10.8 22.0 7.6 15.9 15.1 9.8 6.2 10.4 11.5 10.1 12.9 8.4 33.0 23.4 7.6 11.7 20.3 70.8 13.2 16.1 12.5 8.4 31.1 4.7 17.5 31.0 15.2 9.7 10.4 18.4 23.1 11.4 17.0 21.7 33.7 5.2 11.9 8.2 11.1 14.1 170.2 17.7 13.3 8.8 2.8 23.4 13.2 16.5 2.5 7.5 18.4 8.4 18.4 46.6 26.2 10.2 11.1 6.8 13.7 13.1 18.5 15.5 86.1 48.9 19.3 10.1 26.7 17.1 31.5 14.0 18.9 POMP "C13orf12, HSPC014, UMP1" ENSG00000132963 "Proteasome maturation protein" Q9Y244 13 28659104-28678959 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone "Ichthyosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026995 Approved Supported "Nuclear speckles" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nuclear speckles" "HPA026995: AB_1845546" "unprognostic (2.00e-1)" "unprognostic (3.56e-2)" "unprognostic (2.26e-1)" "unprognostic (3.15e-1)" "unprognostic (8.58e-2)" "prognostic unfavorable (2.05e-5)" "unprognostic (2.71e-3)" "unprognostic (2.50e-2)" "unprognostic (9.90e-2)" "unprognostic (4.35e-2)" "unprognostic (4.83e-2)" "unprognostic (4.93e-1)" "unprognostic (1.39e-3)" "unprognostic (1.70e-2)" "unprognostic (9.41e-2)" "unprognostic (1.03e-2)" "unprognostic (9.81e-2)" 78.9 71.6 77.5 62.9 78.5 66.4 66.7 82.1 101.1 45.1 77.8 66.6 57.0 44.4 78.9 68.7 43.4 46.2 126.3 78.1 83.6 94.1 110.9 65.6 65.4 82.2 83.4 32.9 46.6 51.7 41.7 100.3 83.2 46.6 66.3 56.2 45.1 50.7 175.6 48.5 58.4 57.2 83.6 61.2 54.9 70.0 81.0 64.6 51.4 114.6 70.1 74.0 46.9 86.3 103.4 124.9 129.9 153.1 145.3 161.3 120.3 232.1 203.8 225.5 179.5 245.7 228.7 181.7 136.3 178.6 241.7 150.3 170.7 179.3 307.5 137.7 131.9 171.7 130.1 191.1 203.0 209.6 136.0 131.2 181.9 162.5 149.5 122.3 181.6 139.7 222.2 72.5 291.5 182.5 178.4 295.6 226.1 319.0 146.1 169.6 199.3 122.2 259.6 160.7 152.1 117.1 104.0 147.4 162.2 161.5 103.1 238.5 166.2 108.7 111.2 172.3 195.5 61.5 118.5 255.3 129.2 139.8 243.6 146.4 155.3 101.7 99.9 210.8 88.7 136.4 101.6 113.2 190.8 137.6 71.8 101.9 135.1 95.3 213.9 223.4 132.3 165.2 77.5 78.5 82.1 101.1 78.1 83.6 82.2 83.4 83.2 83.6 81.0 86.3 527.4 131.4 114.2 17.3 218.5 409.8 345.1 1106.2 124.1 110.1 194.3 229.9 806.2 204.5 523.9 239.1 54.2 660.4 255.5 410.0 600.7 566.3 1156.6 266.7 235.8 486.2 228.7 271.5 23.4 699.5 974.0 281.8 128.9 293.0 207.3 181.6 434.1 538.7 780.7 97.6 22.4 315.0 585.9 431.0 673.7 533.7 201.0 407.1 300.6 29.0 612.6 294.7 228.6 13.6 26.1 755.1 414.0 233.6 228.1 443.5 491.8 922.5 472.8 121.8 322.1 193.8 494.6 625.5 240.3 230.1 416.3 972.4 202.7 234.7 335.5 494.3 PPIE "CyP-33, MGC111222, MGC3736" ENSG00000084072 "Peptidylprolyl isomerase E" Q9UNP9 1 39692182-39763914 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Isomerase, RNA-binding, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA019357, HPA020131" Approved Supported "Nuclear speckles" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 72: Non-specific - Transcription" "Cluster 43: THP-1 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" "Nuclear speckles" "HPA019357: AB_2670131, HPA020131: AB_1847405" "unprognostic (2.94e-1)" "unprognostic (4.32e-2)" "unprognostic (6.34e-2)" "unprognostic (6.97e-2)" "unprognostic (5.99e-2)" "unprognostic (8.41e-2)" "prognostic unfavorable (1.76e-4)" "unprognostic (3.52e-2)" "unprognostic (2.69e-1)" "unprognostic (3.88e-3)" "unprognostic (1.25e-1)" "unprognostic (9.29e-2)" "prognostic unfavorable (5.05e-5)" "unprognostic (5.86e-2)" "unprognostic (3.95e-1)" "unprognostic (9.06e-2)" "unprognostic (1.00e-1)" 26.0 27.9 22.3 16.1 22.9 18.5 26.8 22.7 26.5 31.4 20.2 41.1 18.3 33.8 24.9 31.8 35.0 18.1 33.3 22.3 22.8 33.0 33.7 23.3 27.2 22.6 22.0 36.7 40.2 23.8 27.7 20.7 22.9 32.3 22.5 20.9 26.2 23.6 43.1 29.5 29.2 25.4 23.7 32.7 31.7 41.8 22.3 20.6 29.1 30.3 28.2 36.4 29.5 24.6 24.5 34.4 37.2 25.7 40.9 36.9 14.3 40.8 42.7 58.7 56.4 32.8 64.8 68.4 52.2 47.9 34.5 32.8 57.1 52.3 68.8 41.1 38.4 75.6 37.4 9.7 50.9 68.4 36.3 32.8 47.2 53.9 21.0 42.0 54.5 52.8 74.8 39.5 46.6 24.7 34.2 42.1 39.9 49.7 31.5 41.4 28.4 38.4 37.8 37.2 47.7 42.3 43.8 31.5 28.4 49.7 40.9 155.8 35.8 36.3 35.3 48.4 57.1 55.8 66.4 52.5 27.0 86.4 52.3 38.3 62.8 32.6 83.9 64.8 82.8 107.5 89.4 83.8 74.1 109.2 103.5 82.4 6.0 123.2 70.0 63.8 101.3 122.5 22.3 22.9 22.7 26.5 22.3 22.8 22.6 22.0 22.9 23.7 22.3 24.6 28.2 32.1 36.7 10.7 37.0 24.9 43.1 69.8 23.9 25.9 30.3 47.5 31.8 21.5 62.1 33.1 14.6 62.5 39.3 22.8 66.5 57.5 29.2 34.6 27.7 28.7 28.8 38.3 7.7 48.4 59.3 34.0 16.3 23.4 55.2 44.1 37.9 31.1 56.1 23.5 8.8 32.9 40.7 33.4 26.9 76.3 29.8 30.0 39.2 8.4 46.8 34.0 58.7 8.0 13.6 40.0 24.1 45.1 31.7 32.0 39.3 69.8 63.4 29.7 59.2 23.3 40.1 76.1 51.4 24.5 26.3 34.8 36.6 36.3 35.9 32.9 PPIG "CARS-Cyp, SCAF10, SRCyp" ENSG00000138398 "Peptidylprolyl isomerase G" Q13427 2 169584342-169641406 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021788, HPA057469" Supported Supported "Nuclear speckles,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 1: K-562 - Erythropoiesis" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" Cytosol "HPA021788: AB_1847408, HPA057469: AB_2683445" "unprognostic (2.70e-1)" "unprognostic (2.17e-1)" "unprognostic (2.40e-1)" "unprognostic (2.04e-3)" "unprognostic (4.17e-2)" "unprognostic (3.49e-2)" "unprognostic (1.55e-3)" "unprognostic (3.66e-2)" "unprognostic (2.15e-3)" "unprognostic (3.15e-3)" "unprognostic (2.47e-2)" "unprognostic (2.28e-1)" "prognostic unfavorable (4.56e-4)" "unprognostic (5.23e-2)" "unprognostic (3.29e-1)" "unprognostic (3.41e-2)" "unprognostic (3.39e-2)" 26.0 23.2 23.1 28.4 22.1 54.2 27.5 28.8 58.6 27.6 22.9 26.3 26.6 28.8 31.5 27.5 23.6 22.0 25.6 21.5 29.9 29.2 47.1 24.7 36.9 24.6 25.6 26.5 21.2 32.6 25.8 28.0 24.3 27.9 26.0 29.3 26.5 22.9 27.6 25.4 29.7 21.7 22.9 32.3 27.4 20.1 23.7 36.1 29.9 26.2 35.4 26.3 26.5 25.9 56.4 25.5 70.8 35.9 35.4 42.5 63.7 58.9 42.3 45.0 45.9 66.3 58.9 94.8 52.5 44.1 55.5 50.5 56.6 48.4 65.6 68.0 45.7 129.9 36.7 88.3 34.4 136.8 58.9 36.6 54.0 58.5 64.6 40.6 50.4 53.5 142.7 76.2 49.5 43.5 101.0 81.9 100.8 45.3 25.1 90.7 71.7 90.5 53.9 81.2 60.5 41.2 63.4 47.2 68.9 52.9 44.2 78.7 52.7 53.9 43.7 38.4 52.6 41.1 65.3 126.8 38.5 68.1 54.1 31.9 22.5 36.7 22.8 25.1 26.7 32.9 30.9 29.2 18.2 38.4 33.4 27.6 40.4 21.1 31.4 30.0 26.8 17.0 23.1 22.1 28.8 58.6 21.5 29.9 24.6 25.6 24.3 22.9 23.7 25.9 159.7 221.2 175.1 53.5 188.8 151.4 191.4 185.9 101.3 204.6 120.8 156.1 148.4 107.2 169.5 93.8 54.2 170.0 160.1 91.6 80.3 103.1 11.0 104.6 142.3 141.1 104.8 163.5 82.4 103.3 177.0 142.4 66.8 126.3 179.1 115.8 121.7 181.2 151.7 220.4 81.8 135.8 116.0 130.3 126.5 15.6 142.0 129.6 110.3 46.9 152.4 137.6 133.9 53.8 69.7 93.9 118.0 146.7 130.1 161.8 121.1 113.8 132.2 109.1 164.3 150.2 193.9 276.4 183.8 108.3 172.8 205.5 166.7 147.1 149.9 167.7 PPP1R16B "ANKRD4, KIAA0823, TIMAP" ENSG00000101445 "Protein phosphatase 1 regulatory subunit 16B" Q96T49 20 38805697-38923024 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 71.6;lymphoid tissue: 41.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 119.4;Inhibitory neurons: 46.8;Oligodendrocyte precursor cells: 49.8;Oligodendrocytes: 238.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Daudi: 57.3;HMC-1: 59.2;HUVEC TERT2: 35.6;U-266/70: 96.7;U-266/84: 41.8;U-698: 38.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049571, HPA079512" Approved Supported "Nuclear speckles,Plasma membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "Plasma membrane" "Nuclear speckles" "HPA049571: , HPA079512: " "unprognostic (2.62e-2)" "prognostic favorable (2.11e-4)" "unprognostic (2.67e-3)" "unprognostic (3.35e-3)" "unprognostic (2.19e-1)" "prognostic favorable (7.87e-5)" "unprognostic (1.13e-1)" "unprognostic (4.17e-2)" "unprognostic (4.31e-2)" "unprognostic (6.28e-2)" "unprognostic (4.09e-3)" "unprognostic (4.77e-2)" "unprognostic (3.45e-2)" "unprognostic (8.53e-2)" "unprognostic (3.75e-2)" "unprognostic (1.73e-1)" "unprognostic (7.90e-2)" 13.2 2.9 36.5 19.3 71.6 17.7 8.2 26.1 61.1 3.2 5.1 4.6 3.6 3.4 1.5 3.1 5.8 5.3 5.2 49.3 22.3 27.7 2.4 7.9 37.7 27.8 34.7 1.1 1.5 0.8 2.2 3.7 27.1 1.6 5.1 3.7 2.0 1.9 3.6 1.5 18.0 7.2 24.3 18.1 5.6 0.7 35.7 18.2 3.4 5.7 41.9 6.0 1.6 52.1 0.1 0.7 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 57.3 0.8 0.0 0.9 0.1 1.0 0.1 0.0 1.4 0.2 4.4 0.0 0.0 0.0 0.2 59.2 0.0 0.1 0.0 0.0 0.0 35.6 7.6 1.0 11.9 0.0 0.0 7.4 9.7 7.9 0.1 0.0 5.0 0.0 0.0 0.0 0.0 17.7 19.7 0.0 0.0 0.0 0.7 0.0 3.1 5.5 0.0 0.9 0.0 0.0 96.7 41.8 38.3 0.0 0.0 0.1 0.0 0.2 2.5 3.4 0.5 1.8 5.3 2.3 3.3 0.7 3.3 1.3 1.8 0.0 2.9 0.9 3.3 2.6 1.1 36.5 71.6 26.1 61.1 49.3 22.3 27.8 34.7 27.1 24.3 35.7 52.1 29.3 3.2 3.0 1.3 33.6 1.0 0.0 0.8 0.6 2.3 0.5 0.5 23.5 1.5 4.0 0.0 0.0 0.0 34.0 0.3 0.0 0.0 1.9 0.2 0.2 18.7 0.0 2.7 119.4 0.0 0.0 1.6 4.1 0.3 3.8 0.0 38.6 0.3 0.1 37.0 46.8 0.1 0.0 3.1 3.6 1.5 0.0 3.8 8.8 23.4 20.5 0.3 11.3 49.8 238.0 0.0 0.1 0.0 29.3 0.0 0.0 17.4 3.6 0.3 0.0 0.3 1.0 0.0 0.3 0.3 1.3 0.0 37.4 0.0 0.2 0.3 PPP4R3A "FLFL1, FLJ20707, KIAA2010, MSTP033, PP4R3, SMEK1, smk-1, smk1" ENSG00000100796 "Protein phosphatase 4 regulatory subunit 3A" Q6IN85 14 91457508-91510554 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002568, HPA063917" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Nuclear speckles, Cytosol" "HPA002568: AB_1079207, HPA063917: AB_2685153" "unprognostic (5.51e-2)" "unprognostic (2.93e-2)" "unprognostic (3.26e-1)" "unprognostic (1.40e-1)" "unprognostic (4.40e-2)" "unprognostic (9.95e-3)" "unprognostic (4.10e-2)" "unprognostic (5.71e-3)" "unprognostic (1.05e-1)" "unprognostic (8.34e-3)" "unprognostic (1.33e-1)" "unprognostic (3.85e-2)" "unprognostic (3.07e-1)" "unprognostic (1.13e-1)" "unprognostic (2.57e-1)" "unprognostic (1.57e-1)" "unprognostic (4.53e-2)" 19.3 13.5 14.4 18.2 14.5 50.0 19.6 16.6 15.2 19.1 16.2 21.2 17.2 20.0 15.9 21.4 20.4 12.3 16.2 12.6 13.3 18.3 23.7 20.2 28.3 13.6 14.2 22.0 19.8 16.8 14.8 17.5 13.7 18.4 18.5 10.9 20.8 13.1 24.5 25.4 24.4 15.0 12.7 24.1 20.6 22.3 14.5 27.4 17.7 16.7 25.4 19.5 19.4 16.9 24.5 41.4 34.1 27.1 22.5 20.9 60.9 23.2 21.4 24.5 24.6 35.2 32.1 63.1 30.2 19.2 15.0 27.8 36.6 28.9 39.8 52.0 19.7 32.5 25.7 24.5 26.3 59.1 33.1 15.1 50.4 19.7 31.1 20.1 26.7 29.4 33.5 36.2 33.1 52.1 42.8 38.0 31.2 46.5 29.8 54.0 40.6 26.5 30.3 41.5 41.6 25.4 35.3 77.0 32.5 33.6 39.4 37.8 28.0 19.2 20.6 21.1 26.8 36.0 67.0 69.3 25.2 31.8 34.7 6.2 1.9 2.9 4.9 2.6 6.6 4.6 4.5 4.4 2.1 7.4 5.6 4.8 2.5 9.0 3.7 5.0 6.9 2.6 14.4 14.5 16.6 15.2 12.6 13.3 13.6 14.2 13.7 12.7 14.5 16.9 44.1 32.1 48.3 0.0 83.0 0.0 46.7 0.0 58.1 27.9 35.9 23.5 0.0 32.9 30.3 46.0 20.9 33.9 91.8 21.1 29.4 21.2 13.0 86.9 46.5 33.3 13.3 47.5 0.0 25.1 29.0 27.3 45.3 70.7 20.2 39.8 28.9 51.8 25.8 32.0 0.0 28.2 0.0 48.7 0.0 8.5 37.6 70.7 0.0 0.0 41.8 21.0 44.3 0.0 0.0 27.8 25.7 42.5 75.8 56.6 37.3 23.5 16.8 27.3 26.3 45.9 27.1 91.0 59.9 58.0 0.0 44.3 80.1 33.0 25.8 75.2 PPP4R3B "FLFL2, FLJ31474, KIAA1387, PSY2, SMEK2" ENSG00000275052 "Protein phosphatase 4 regulatory subunit 3B" Q5MIZ7 2 55547292-55618880 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001233, CAB017185" Approved Supported "Nucleoplasm,Nuclear speckles,Centrosome" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Nuclear speckles" Centrosome "CAB017185: , HPA001233: AB_1080033" "unprognostic (9.60e-2)" "unprognostic (2.47e-2)" "unprognostic (5.77e-2)" "unprognostic (1.87e-2)" "unprognostic (6.34e-2)" "unprognostic (3.56e-1)" "unprognostic (2.66e-2)" "unprognostic (3.27e-2)" "unprognostic (8.27e-3)" "unprognostic (7.62e-2)" "unprognostic (1.07e-2)" "unprognostic (3.69e-1)" "prognostic unfavorable (6.03e-4)" "unprognostic (9.73e-2)" "unprognostic (1.45e-1)" "unprognostic (6.28e-2)" "unprognostic (2.77e-1)" 29.0 27.4 14.8 28.2 15.1 25.8 29.1 20.9 16.9 26.8 20.0 28.1 31.6 23.7 19.3 31.7 32.3 24.7 14.3 13.8 16.9 33.4 48.0 23.4 38.1 15.0 16.3 25.7 32.1 27.4 12.5 24.5 16.2 24.9 27.7 35.3 28.1 23.2 14.7 29.6 32.1 21.8 15.9 28.7 30.8 23.7 15.1 42.2 33.0 20.3 38.7 26.7 16.9 18.7 42.8 33.0 35.6 30.0 37.2 38.9 49.1 34.0 35.9 28.2 24.0 39.5 40.9 57.7 67.5 32.7 44.8 36.4 39.9 27.5 41.4 84.6 16.7 56.7 30.0 52.9 60.3 66.0 45.6 29.8 64.9 34.1 60.1 36.9 45.0 31.6 55.2 57.4 37.7 50.9 42.8 43.7 35.1 55.9 25.3 40.1 53.6 44.6 39.3 43.8 43.4 26.9 36.8 49.9 54.8 23.5 31.6 52.0 36.3 43.3 56.8 21.6 47.2 59.1 47.3 22.3 40.8 61.3 47.2 25.6 16.5 26.9 20.4 20.9 23.2 18.1 21.2 21.6 18.4 18.6 24.5 21.5 19.6 22.5 23.0 9.9 24.0 23.9 14.8 15.1 20.9 16.9 13.8 16.9 15.0 16.3 16.2 15.9 15.1 18.7 46.8 44.8 41.3 0.0 61.8 0.0 48.9 0.0 44.3 44.1 42.7 27.9 0.0 31.5 29.1 16.5 33.3 30.6 51.4 25.3 39.2 32.4 9.5 85.1 43.2 32.9 18.2 46.7 0.0 41.0 28.5 33.9 43.8 39.6 30.3 39.0 26.0 52.5 26.2 53.8 0.0 29.4 0.0 37.7 0.0 7.6 28.0 44.9 0.0 0.0 47.9 53.1 49.4 0.0 0.0 35.4 24.1 36.1 57.2 57.4 46.1 52.9 62.7 38.5 6.6 54.9 28.4 39.1 25.7 53.3 0.0 47.7 56.3 44.6 29.0 57.2 PRKAA1 AMPKa1 ENSG00000132356 "Protein kinase AMP-activated catalytic subunit alpha 1" Q13131 5 40759379-40798374 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Autophagy, Biological rhythms, Cholesterol biosynthesis, Cholesterol metabolism, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism, Transcription, Transcription regulation, Wnt signaling pathway" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 292.5;Late spermatids: 478.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005050, HPA035409, HPA064946" Supported Supported "Nuclear speckles,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 31: Spermatids - Spermatogenesis" "Nuclear speckles" Cytosol "CAB005050: AB_562037, HPA035409: AB_2674613, HPA064946: AB_2685390" "unprognostic (2.07e-1)" "unprognostic (1.41e-2)" "unprognostic (2.51e-2)" "unprognostic (3.57e-2)" "unprognostic (3.97e-1)" "unprognostic (1.05e-1)" "unprognostic (3.51e-2)" "unprognostic (7.53e-2)" "unprognostic (1.66e-2)" "unprognostic (2.88e-1)" "unprognostic (3.34e-3)" "unprognostic (2.63e-1)" "unprognostic (2.82e-2)" "unprognostic (1.35e-1)" "unprognostic (1.60e-1)" "unprognostic (1.27e-2)" "unprognostic (1.10e-2)" 33.3 21.0 7.9 27.2 9.6 52.6 30.2 10.3 11.0 26.7 12.3 30.0 35.4 26.3 18.6 20.6 21.0 33.5 20.2 6.9 11.3 32.0 49.9 27.4 29.2 11.8 9.9 19.1 23.1 32.0 9.2 21.2 12.2 31.9 34.7 19.0 27.4 24.7 16.9 23.1 30.9 26.4 10.2 27.8 33.7 41.1 10.0 21.8 32.3 19.9 23.9 28.8 17.8 10.3 28.4 28.9 22.8 30.2 55.0 57.0 21.6 47.3 48.1 34.7 30.8 27.6 35.9 16.6 21.4 48.8 45.3 22.4 21.3 43.1 64.9 49.2 19.2 33.1 66.1 22.1 45.3 31.9 33.5 52.8 20.6 46.5 47.5 38.4 52.1 21.0 15.9 46.7 52.4 13.6 29.7 24.9 9.9 28.9 34.6 24.5 48.7 24.6 53.3 47.5 19.6 19.7 83.0 54.3 28.8 12.3 28.4 26.0 56.0 62.1 33.5 36.2 39.2 18.5 15.4 19.6 38.9 67.9 33.9 17.0 6.5 12.8 8.9 7.9 11.5 8.2 8.4 8.6 6.4 7.9 10.1 9.0 15.4 10.9 9.3 1.9 11.6 6.5 7.9 9.6 10.3 11.0 6.9 11.3 11.8 9.9 12.2 10.2 10.0 10.3 47.3 41.7 26.5 19.2 34.1 24.1 24.7 40.5 15.4 20.3 36.1 17.9 18.3 42.9 43.4 47.8 35.5 13.8 45.8 44.1 7.9 27.9 292.5 19.7 35.8 42.4 21.1 25.4 24.5 44.9 13.7 36.2 36.7 20.7 18.3 17.8 37.1 83.4 20.0 15.2 30.3 28.8 42.7 25.3 28.5 478.5 30.4 24.1 35.6 24.4 40.9 15.4 44.3 30.7 43.8 36.0 32.8 25.9 23.4 33.4 33.7 35.4 42.9 27.9 0.0 22.7 43.1 82.8 17.6 19.9 32.7 18.6 44.0 19.2 36.9 35.0 PRKAA2 "AMPK, AMPKa2, PRKAA" ENSG00000162409 "Protein kinase AMP-activated catalytic subunit alpha 2" P54646 1 56645314-56715335 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Autophagy, Biological rhythms, Cholesterol biosynthesis, Cholesterol metabolism, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism, Transcription, Transcription regulation, Wnt signaling pathway" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 40.8;skeletal muscle: 38.7;tongue: 36.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 328.5;Excitatory neurons: 109.4;Inhibitory neurons: 119.0;Oligodendrocyte precursor cells: 84.9;Rod photoreceptor cells: 115.5" "Cancer enhanced" "Detected in many" "renal cancer: 5.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 14.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044540 Approved Supported "Nuclear speckles,Golgi apparatus" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nuclear speckles" "Golgi apparatus" "HPA044540: AB_2678977" "unprognostic (4.17e-3)" "unprognostic (1.62e-2)" "unprognostic (4.17e-1)" "prognostic unfavorable (4.80e-4)" "unprognostic (9.35e-2)" "unprognostic (1.92e-3)" "prognostic unfavorable (5.30e-4)" "unprognostic (7.30e-2)" "unprognostic (3.94e-1)" "unprognostic (1.82e-1)" "unprognostic (1.97e-1)" "unprognostic (8.64e-2)" "prognostic favorable (4.95e-5)" "unprognostic (1.30e-2)" "unprognostic (4.52e-2)" "unprognostic (1.57e-2)" "unprognostic (1.85e-1)" 1.4 1.4 2.0 0.5 3.5 0.0 3.3 3.0 3.5 1.4 4.1 5.0 0.5 1.8 1.1 4.7 2.7 1.9 40.8 3.9 2.1 13.6 0.7 1.4 0.1 0.9 1.3 1.5 1.8 8.3 1.3 0.5 0.9 3.8 1.4 13.5 4.3 2.6 38.7 0.7 1.3 3.1 0.3 1.3 2.2 1.1 1.3 0.4 3.3 36.4 0.1 1.8 1.3 1.5 0.0 3.8 2.1 0.0 0.7 0.5 2.3 1.9 1.5 2.5 4.3 3.9 4.9 0.0 0.6 0.6 7.5 0.1 8.0 0.0 7.1 0.0 8.8 0.0 7.0 5.5 0.0 0.0 0.1 0.6 0.0 3.5 0.3 5.8 0.8 2.0 0.0 0.0 1.1 0.1 0.0 0.0 5.6 0.0 5.5 0.0 0.0 0.0 14.1 1.3 2.0 5.5 6.0 0.1 0.0 6.0 3.3 0.0 0.0 1.5 2.3 2.8 6.6 0.0 0.0 0.0 4.5 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 3.5 3.0 3.5 3.9 2.1 0.9 1.3 0.9 0.3 1.3 1.5 1.1 9.6 4.8 30.7 2.0 0.9 8.0 6.7 2.2 42.0 19.4 9.5 328.5 24.3 14.3 49.7 50.1 1.0 0.2 6.1 54.8 9.5 3.9 14.4 2.9 10.3 14.4 0.0 109.4 4.8 0.4 15.3 5.1 17.4 2.5 11.7 9.7 8.1 0.1 26.9 119.0 6.3 8.2 0.0 1.6 4.8 6.8 1.4 5.4 18.7 0.0 18.6 0.0 84.9 20.4 6.2 3.0 29.3 0.0 21.2 0.2 82.4 10.7 115.5 6.6 24.5 17.2 7.2 3.7 17.7 0.4 0.4 1.2 5.3 6.1 13.4 PRKN "AR-JP, PARK2, parkin, PDJ" ENSG00000185345 "Parkin RBR E3 ubiquitin protein ligase" O60260 6 161347417-162727775 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 28.3;tongue: 15.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Alveolar cells type 2: 4.8;Distal tubular cells: 19.6;Proximal tubular cells: 6.8" "Cancer enhanced" "Detected in many" "renal cancer: 3.3" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AN3-CA: 2.0;HEL: 4.1;HSkMC: 1.7;Karpas-707: 2.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB016257, HPA036012" Enhanced Supported "Nuclear speckles,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 39: Non-specific - Basic cellular processes" "Nuclear speckles" Cytosol "CAB016257: AB_628104, HPA036012: AB_2732471" "unprognostic (9.23e-2)" "unprognostic (3.29e-2)" "unprognostic (6.48e-2)" "unprognostic (2.69e-3)" "unprognostic (9.85e-2)" "unprognostic (5.85e-2)" "unprognostic (7.07e-2)" "unprognostic (1.12e-1)" "unprognostic (1.39e-1)" "unprognostic (2.68e-2)" "unprognostic (1.03e-3)" "unprognostic (8.16e-2)" "prognostic favorable (6.75e-12)" "unprognostic (9.93e-2)" "unprognostic (1.51e-1)" "unprognostic (5.24e-2)" "unprognostic (2.50e-1)" 3.4 3.3 4.1 0.1 3.6 0.3 1.9 0.4 5.7 1.3 0.6 2.7 1.2 1.6 1.2 3.2 1.2 1.5 9.1 4.6 1.8 5.2 1.2 1.0 0.5 1.0 1.9 2.8 1.2 2.3 1.8 0.4 1.6 1.2 0.6 1.5 1.3 1.4 28.3 2.0 1.0 1.2 1.0 1.0 1.9 5.3 1.9 0.5 1.3 15.9 0.3 2.5 1.0 2.4 0.0 0.0 0.3 2.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.5 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.5 4.1 0.1 0.6 0.3 0.0 0.0 1.7 0.0 0.0 0.2 0.3 0.0 0.2 0.2 2.2 0.0 0.2 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.7 0.0 0.0 0.5 1.0 0.0 0.2 0.2 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.7 1.7 0.3 2.2 0.8 0.1 1.3 0.6 0.8 0.9 0.7 1.6 1.8 1.8 0.5 0.6 0.4 0.0 0.1 0.8 4.1 3.6 0.4 5.7 4.6 1.8 1.0 1.9 1.6 1.0 1.9 2.4 2.3 9.6 4.8 0.0 0.6 0.0 0.0 0.0 0.0 0.0 2.1 1.5 0.0 0.0 1.8 1.8 0.0 0.5 0.4 0.0 19.6 1.1 0.0 3.4 1.8 0.7 0.0 0.0 0.0 2.2 0.1 1.8 0.0 3.2 2.5 3.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 6.8 1.5 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.3 0.4 3.7 0.0 0.0 PRPF4B "KIAA0536, PR4H, Prp4" ENSG00000112739 "Pre-mRNA processing factor 4B" Q13523 6 4021267-4064983 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020638 Approved Supported "Nuclear speckles" NA NA "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "HPA020638: AB_1855774" "unprognostic (1.03e-1)" "unprognostic (2.66e-1)" "unprognostic (4.95e-2)" "unprognostic (2.20e-1)" "unprognostic (3.59e-3)" "unprognostic (1.21e-2)" "prognostic unfavorable (2.27e-4)" "unprognostic (8.68e-3)" "unprognostic (3.41e-2)" "unprognostic (4.45e-3)" "unprognostic (2.17e-1)" "unprognostic (1.07e-1)" "unprognostic (9.50e-3)" "unprognostic (8.90e-2)" "unprognostic (2.34e-1)" "unprognostic (7.63e-3)" "prognostic favorable (6.82e-5)" 9.1 7.2 4.8 11.3 5.4 27.3 8.1 7.5 6.7 5.8 5.2 8.6 10.2 9.9 10.1 8.4 4.4 6.1 5.0 4.7 5.1 4.2 4.3 6.8 14.2 5.4 5.5 8.4 6.8 4.2 3.3 7.6 5.3 6.3 8.6 15.9 8.4 5.5 16.3 13.3 9.0 5.6 4.9 11.2 8.1 3.8 5.5 8.8 6.5 4.5 10.0 6.7 7.0 6.9 6.0 3.9 14.4 12.1 8.3 7.3 12.3 7.7 3.4 4.7 5.2 6.9 7.1 8.1 5.7 5.1 4.8 12.8 10.1 6.8 7.1 4.4 11.1 6.7 19.1 11.5 3.6 11.2 10.6 5.7 6.9 5.4 6.6 11.0 5.1 6.5 11.6 3.1 7.4 2.7 7.2 26.3 6.0 3.8 4.3 9.9 6.1 11.2 8.4 10.2 7.9 7.3 4.7 3.9 5.5 16.9 9.6 7.9 7.3 11.2 6.5 4.3 8.2 7.5 7.9 6.9 3.2 7.6 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 5.4 7.5 6.7 4.7 5.1 5.4 5.5 5.3 4.9 5.5 6.9 122.4 109.0 103.2 35.6 110.5 83.5 64.0 43.1 69.4 88.6 80.4 49.5 79.1 61.5 75.1 97.5 89.6 61.8 151.3 94.9 72.4 64.4 15.6 115.9 143.5 85.8 75.3 79.1 42.8 56.8 49.9 78.7 88.2 113.4 90.5 96.2 61.1 85.8 41.1 106.0 49.8 88.8 50.8 71.6 49.4 20.6 98.8 71.4 35.6 49.6 97.4 81.2 118.4 50.8 68.1 62.8 61.5 89.1 101.9 62.8 55.5 89.5 71.7 184.0 59.2 105.3 85.8 66.1 76.5 66.7 91.4 63.6 106.2 93.1 87.7 65.2 PRPF6 "ANT-1, bB152O15.1, C20orf14, hPrp6, Prp6, RP60, SNRNP102, TOM, U5-102K" ENSG00000101161 "Pre-mRNA processing factor 6" O94906 20 63981132-64033100 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047106 Supported Supported "Nuclear speckles" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 39: CACO-2 - Unknown function" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "HPA047106: AB_10963084" "unprognostic (1.29e-1)" "unprognostic (9.96e-3)" "unprognostic (7.02e-2)" "unprognostic (9.36e-3)" "unprognostic (1.80e-1)" "unprognostic (2.34e-1)" "unprognostic (1.66e-3)" "unprognostic (3.37e-2)" "unprognostic (1.44e-2)" "unprognostic (1.14e-1)" "unprognostic (5.76e-3)" "unprognostic (2.18e-1)" "unprognostic (3.16e-3)" "unprognostic (6.16e-2)" "unprognostic (8.04e-2)" "unprognostic (7.19e-2)" "unprognostic (5.39e-3)" 44.0 32.2 33.6 30.8 37.4 33.3 40.1 44.9 37.1 38.5 34.5 39.9 30.0 43.5 27.9 38.9 49.3 27.2 39.0 32.9 34.7 35.3 29.8 32.1 40.9 37.7 35.5 50.6 44.2 37.2 36.7 30.9 37.1 34.5 25.9 36.4 38.3 36.4 64.6 58.3 38.1 29.7 34.6 40.9 37.3 41.0 35.5 44.4 36.2 37.1 40.5 40.5 36.2 46.8 72.8 86.5 62.3 66.3 69.5 48.6 81.5 56.1 62.8 167.9 74.6 233.6 86.2 90.9 133.4 74.5 107.1 110.0 101.2 116.1 88.7 44.0 59.0 76.8 112.7 213.3 76.7 105.3 102.3 55.2 81.4 77.5 89.2 59.9 63.3 83.7 76.2 76.6 56.8 89.2 106.8 131.0 55.4 114.4 106.7 116.0 53.0 87.3 64.4 71.9 61.8 72.4 108.6 110.0 74.1 43.2 108.0 135.5 90.1 96.2 55.1 77.4 104.6 63.7 66.5 94.6 70.3 62.5 76.3 90.8 59.7 73.7 67.0 62.7 93.3 67.1 82.3 72.5 58.6 58.4 95.8 80.9 50.3 130.5 77.8 54.5 79.7 92.3 33.6 37.4 44.9 37.1 32.9 34.7 37.7 35.5 37.1 34.6 35.5 46.8 60.7 60.9 62.6 19.2 69.3 38.4 45.3 50.7 63.2 81.6 54.2 59.8 70.5 34.3 71.6 62.5 37.5 72.5 53.2 43.8 82.2 59.3 49.1 70.3 66.8 55.7 52.7 43.5 12.5 56.7 47.6 51.2 38.7 62.0 91.2 49.0 63.9 55.2 46.3 42.1 14.8 60.6 57.0 44.8 34.1 28.7 58.1 49.9 48.0 5.6 79.7 86.5 57.7 12.5 17.8 65.9 43.9 52.6 67.8 33.5 58.0 65.8 87.7 112.7 59.2 68.2 61.9 120.6 118.9 59.8 46.3 94.5 60.0 32.6 47.7 34.3 PSKH1 ENSG00000159792 "Protein serine kinase H1" P11801 16 67893254-67929676 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053927, HPA062763" Approved Supported "Nuclear speckles,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 40: Granulosa cells - Unknown function" "Nuclear speckles, Cytosol" "HPA053927: AB_2682312, HPA062763: " "unprognostic (2.57e-2)" "unprognostic (8.91e-3)" "unprognostic (1.88e-1)" "unprognostic (5.79e-2)" "unprognostic (3.26e-1)" "unprognostic (3.89e-1)" "unprognostic (1.64e-1)" "unprognostic (1.29e-2)" "unprognostic (3.03e-1)" "unprognostic (1.66e-2)" "unprognostic (9.85e-3)" "unprognostic (8.32e-2)" "prognostic favorable (4.28e-10)" "unprognostic (1.46e-1)" "unprognostic (1.99e-1)" "unprognostic (4.15e-2)" "unprognostic (3.90e-3)" 14.3 18.6 12.8 9.6 14.5 5.2 14.0 12.2 13.5 13.5 19.5 18.2 13.7 19.3 10.0 16.9 18.7 10.1 17.6 11.2 11.5 20.5 16.5 12.7 10.6 15.0 14.9 19.4 26.3 32.9 13.2 7.6 13.4 15.1 10.8 4.0 18.1 12.7 15.3 13.8 15.7 15.7 13.2 12.8 21.4 21.8 13.6 12.0 15.0 13.5 8.5 16.5 9.5 14.9 13.0 22.7 25.2 28.1 38.4 19.3 16.3 15.2 23.0 15.8 14.0 17.2 18.2 12.2 22.7 25.7 12.7 19.2 14.7 15.6 5.3 4.8 16.4 13.9 16.8 22.0 26.3 13.4 8.0 35.7 26.7 18.8 19.6 21.3 23.3 22.5 21.6 5.1 16.7 28.7 18.3 8.6 24.2 14.0 13.9 27.7 9.7 25.3 18.6 16.0 21.8 26.0 47.3 12.8 15.8 9.9 23.5 23.9 20.8 17.7 6.2 15.0 7.7 15.3 8.7 26.2 21.4 8.8 19.9 0.0 2.0 1.9 2.0 2.2 1.4 1.5 1.5 2.0 2.1 1.2 1.2 1.7 1.0 2.1 1.5 1.5 0.8 1.7 12.8 14.5 12.2 13.5 11.2 11.5 15.0 14.9 13.4 13.2 13.6 14.9 5.5 0.0 3.6 4.6 2.9 1.1 3.1 5.2 2.2 11.1 5.3 4.6 2.3 7.2 3.8 5.5 6.2 6.2 3.0 11.5 11.7 6.0 14.4 5.8 6.5 5.2 10.8 3.0 4.6 7.4 4.8 5.4 5.1 4.8 6.3 13.0 5.3 10.3 4.8 6.7 6.1 6.2 10.2 6.3 1.6 22.1 4.7 2.9 5.4 3.7 4.8 11.0 3.1 5.5 9.2 7.6 4.5 7.9 3.0 3.6 10.0 8.1 4.9 6.9 13.1 6.3 6.1 6.7 6.1 5.4 1.6 5.9 3.8 10.7 7.4 2.2 RADX "CXorf57, FLJ10178, FLJ14191" ENSG00000147231 "RPA1 related single stranded DNA binding protein, X-linked" Q6NSI4 X 106611930-106679439 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.3;pituitary gland: 20.3" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 12.3;Extravillous trophoblasts: 4.7;Syncytiotrophoblasts: 22.6" "Cancer enhanced" "Detected in many" "urothelial cancer: 4.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 10 "B-cells: 1.8;NK-cells: 1.0;T-cells: 1.6" "Cell line enhanced" "Detected in many" "HEK 293: 37.2;RT4: 39.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA000896, HPA001010, HPA001374" Uncertain Supported "Nuclear speckles" NA No "Cluster 40: NK-cells - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nuclear speckles" "HPA000896: AB_1078880, HPA001010: , HPA001374: AB_2666288" "unprognostic (3.30e-2)" "unprognostic (5.59e-3)" "unprognostic (2.67e-2)" "unprognostic (1.46e-3)" "unprognostic (4.85e-2)" "unprognostic (8.26e-2)" "unprognostic (1.24e-2)" "unprognostic (1.89e-1)" "unprognostic (3.02e-1)" "unprognostic (5.49e-2)" "unprognostic (3.81e-3)" "unprognostic (1.17e-1)" "unprognostic (4.20e-3)" "unprognostic (1.63e-1)" "unprognostic (2.70e-1)" "unprognostic (2.21e-2)" "unprognostic (1.23e-3)" 1.0 7.2 6.1 1.4 5.6 0.6 1.4 2.5 4.5 3.7 1.7 1.2 1.1 3.2 2.1 1.0 3.8 0.6 1.1 3.4 27.3 2.5 1.4 2.4 3.3 4.5 4.9 6.7 1.9 0.8 20.3 3.6 6.1 0.8 0.8 1.8 0.8 1.2 1.8 2.5 1.8 0.9 3.6 2.3 2.6 3.9 20.6 2.3 3.0 1.0 2.1 2.5 1.9 5.3 7.2 0.0 7.2 10.1 4.0 3.4 10.8 0.3 1.4 0.0 0.1 1.6 1.5 15.0 0.0 0.8 7.7 2.0 18.6 3.2 0.0 0.0 37.2 5.0 0.0 0.4 0.2 0.0 3.2 2.0 2.2 0.5 1.3 1.9 0.0 13.1 0.2 19.1 1.6 0.0 14.0 0.0 6.5 4.8 1.1 0.0 6.7 0.0 3.1 39.9 11.8 0.0 0.7 0.2 4.3 5.5 1.8 0.2 0.0 3.1 2.6 0.0 4.5 6.8 3.1 18.5 5.5 0.0 5.3 0.0 0.0 0.0 1.5 0.0 1.1 1.8 1.3 1.0 0.0 1.3 1.6 1.3 0.1 1.0 0.0 0.1 0.5 0.4 6.1 5.6 2.5 4.5 3.4 27.3 4.5 4.9 6.1 3.6 20.6 5.3 0.8 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 12.3 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 22.6 1.0 0.0 0.0 0.0 RBM14 "COAA, DKFZp779J0927, SIP, SYTIP1" ENSG00000239306 "RNA binding motif protein 14" Q96PK6 11 66616626-66629934 "Predicted intracellular proteins" "Immunity, Innate immunity, Transcription, Transcription regulation" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006628 Supported Supported "Nuclear speckles" NA NA 31000 "Cluster 39: Non-specific - mRNA processing" "Cluster 43: Testis - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 39: Non-specific - Basic cellular processes" "Nuclear speckles" "HPA006628: AB_1078546" "unprognostic (6.96e-2)" "unprognostic (4.79e-2)" "unprognostic (4.34e-3)" "unprognostic (4.45e-2)" "unprognostic (2.15e-1)" "unprognostic (9.56e-3)" "prognostic unfavorable (2.02e-7)" "unprognostic (4.21e-2)" "unprognostic (1.54e-3)" "unprognostic (1.08e-2)" "prognostic favorable (1.04e-4)" "unprognostic (9.38e-3)" "unprognostic (8.59e-3)" "unprognostic (1.29e-2)" "unprognostic (3.32e-1)" "unprognostic (1.02e-1)" "unprognostic (1.94e-1)" 26.9 32.0 39.9 25.0 40.2 32.6 24.1 52.6 48.0 37.2 48.5 29.4 15.7 30.8 19.1 33.9 37.6 10.7 33.2 40.1 38.9 50.6 40.4 27.3 28.3 39.4 40.6 45.1 34.1 17.5 34.5 19.6 39.4 36.3 18.2 35.8 25.3 14.6 29.7 28.4 29.1 15.6 37.1 40.4 30.1 44.0 39.6 25.7 28.4 11.6 29.2 30.4 28.6 48.6 83.0 77.9 55.9 43.2 25.3 16.8 97.0 45.0 16.4 40.8 24.0 79.2 60.6 130.9 49.2 21.9 45.0 69.0 63.4 36.5 43.3 63.9 68.7 81.7 67.1 71.2 14.1 71.5 70.0 11.8 13.3 41.9 23.3 24.1 31.0 38.2 98.6 83.9 40.2 70.3 122.4 79.4 107.2 69.0 85.7 125.3 65.4 67.3 34.2 71.5 67.0 61.9 78.0 55.9 33.9 45.9 77.3 63.5 50.5 49.4 97.9 40.5 72.6 49.8 75.2 109.0 41.8 68.9 120.1 19.7 24.3 27.3 27.9 26.1 27.2 21.3 24.1 26.8 33.6 21.8 24.3 28.2 9.0 21.7 27.2 21.3 23.1 34.0 39.9 40.2 52.6 48.0 40.1 38.9 39.4 40.6 39.4 37.1 39.6 48.6 12.6 9.6 17.0 0.0 27.4 38.1 45.7 20.7 15.4 24.8 19.1 16.3 16.3 18.6 17.2 14.7 29.2 56.3 32.7 17.7 17.6 26.5 37.3 18.1 16.5 21.3 21.6 23.1 0.0 18.4 54.4 20.1 9.7 17.5 19.7 20.4 22.5 24.5 29.0 11.8 0.0 20.9 24.4 16.0 30.2 27.0 17.1 20.1 12.4 0.0 25.4 18.1 34.0 0.0 0.0 19.3 21.7 16.1 20.7 26.9 19.0 12.2 23.2 49.4 6.6 15.1 21.5 53.9 40.1 20.9 31.1 69.2 29.0 13.7 25.2 32.6 RBM39 "CAPER, CAPERalpha, CC1.3, fSAP59, HCC1, RNPC2" ENSG00000131051 "RNA binding motif protein 39" Q14498 20 35701347-35742312 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001591 Supported Supported "Nucleoplasm,Nuclear speckles,Microtubules,Centriolar satellite" NA NA 19000 "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nuclear speckles" "Microtubules, Centriolar satellite" "HPA001591: AB_1079749" "unprognostic (1.37e-2)" "unprognostic (4.97e-1)" "unprognostic (2.72e-2)" "unprognostic (9.09e-2)" "unprognostic (3.47e-1)" "unprognostic (4.99e-2)" "unprognostic (3.55e-3)" "unprognostic (4.56e-2)" "unprognostic (7.83e-2)" "unprognostic (2.65e-1)" "unprognostic (2.04e-2)" "unprognostic (7.65e-3)" "prognostic unfavorable (2.78e-5)" "unprognostic (1.88e-1)" "unprognostic (2.86e-1)" "unprognostic (2.64e-1)" "unprognostic (2.28e-3)" 70.1 55.8 18.4 37.7 17.6 172.0 44.6 33.5 28.0 57.8 22.2 56.0 35.1 54.5 9.2 62.3 61.4 40.8 57.3 16.5 25.0 52.2 47.7 62.2 42.3 24.2 24.0 71.1 41.2 27.3 50.0 40.9 19.4 50.2 16.9 49.5 53.4 22.3 70.3 51.2 46.9 19.2 16.0 56.4 49.7 34.3 16.9 51.1 54.2 33.1 24.1 50.7 62.1 26.5 98.8 87.6 77.0 78.5 48.8 53.8 78.8 131.0 50.6 59.6 60.2 109.3 78.5 137.5 90.6 38.9 67.9 91.2 122.3 67.9 66.5 94.6 96.7 174.6 80.7 101.2 23.4 158.6 99.9 14.4 97.6 68.9 38.4 63.7 57.8 46.4 195.5 117.6 46.3 72.2 194.5 87.9 103.2 87.5 96.8 104.9 136.2 91.7 41.5 56.2 77.9 63.4 91.1 94.7 78.4 109.3 70.6 94.6 91.4 100.8 92.5 90.5 115.8 71.6 164.3 204.0 64.7 123.2 79.2 250.9 120.4 197.5 104.7 111.1 103.6 131.1 91.5 97.6 111.8 140.5 85.7 82.1 427.7 127.2 102.2 160.9 114.7 95.7 18.4 17.6 33.5 28.0 16.5 25.0 24.2 24.0 19.4 16.0 16.9 26.5 302.0 233.9 280.9 144.3 441.7 616.4 521.0 283.0 284.0 258.5 339.1 295.4 189.2 191.6 267.6 200.5 316.9 375.2 624.9 278.1 189.8 203.8 48.1 359.2 496.0 299.7 295.3 214.2 130.1 186.0 389.6 337.9 254.9 540.8 525.8 304.4 215.3 202.1 199.8 220.4 120.9 331.3 215.7 207.7 469.5 41.9 262.5 335.5 270.3 129.3 274.3 208.7 400.6 136.2 160.5 221.3 254.8 214.4 391.0 453.6 271.8 150.6 248.0 386.5 164.3 504.0 410.2 263.5 228.1 215.8 586.9 561.6 490.8 218.2 282.8 532.1 RBM8A "BOV-1A, BOV-1B, BOV-1C, RBM8, RBM8B, Y14, ZNRP" ENSG00000265241 "RNA binding motif protein 8A" Q9Y5S9 1 145917714-145927678 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA processing, mRNA splicing, mRNA transport, Nonsense-mediated mRNA decay, Translation regulation, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 735.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018403 Supported Supported "Nuclear speckles" NA NA 100000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Nuclear speckles" "HPA018403: AB_1858908" "unprognostic (3.81e-1)" "unprognostic (3.99e-3)" "unprognostic (1.59e-1)" "unprognostic (6.83e-2)" "unprognostic (1.12e-1)" "unprognostic (3.16e-1)" "unprognostic (4.62e-3)" "unprognostic (1.91e-1)" "unprognostic (1.38e-1)" "unprognostic (8.79e-3)" "unprognostic (7.27e-3)" "prognostic unfavorable (1.55e-4)" "unprognostic (3.30e-3)" "unprognostic (2.18e-1)" "unprognostic (3.77e-2)" "unprognostic (2.02e-1)" "unprognostic (1.64e-3)" 86.1 74.9 37.2 105.4 39.1 214.7 82.3 38.7 43.0 69.6 35.6 70.5 70.1 67.7 49.3 163.6 62.2 58.0 73.0 36.8 41.7 81.6 77.5 72.8 126.4 39.7 39.8 72.0 59.9 78.4 65.8 85.3 40.8 66.4 56.4 45.0 79.2 48.2 214.9 92.0 69.2 57.7 42.1 81.6 67.5 71.3 40.0 120.7 68.8 100.1 123.7 112.8 80.4 43.9 377.0 300.7 268.8 215.7 94.6 92.2 330.0 224.3 150.7 315.0 230.1 400.0 277.4 342.0 344.9 155.3 166.5 252.5 289.3 245.3 257.0 305.6 275.7 264.2 229.2 299.8 133.6 446.6 222.6 102.2 180.8 283.0 300.3 137.4 238.1 291.9 405.2 314.7 246.2 1033.8 452.3 352.2 463.7 323.9 518.4 394.4 234.6 341.2 203.2 355.6 274.6 335.7 334.5 169.7 316.5 231.0 318.0 534.3 247.3 252.3 324.0 250.9 626.0 352.2 603.4 502.6 226.4 264.9 223.2 464.6 316.5 513.6 337.2 363.9 322.1 444.3 317.6 346.4 318.0 389.6 296.1 328.3 363.7 389.8 361.3 498.4 386.3 582.7 37.2 39.1 38.7 43.0 36.8 41.7 39.7 39.8 40.8 42.1 40.0 43.9 289.1 70.5 132.4 8.1 251.0 332.9 396.7 475.4 244.2 66.3 168.5 184.7 78.0 98.7 262.8 88.3 54.2 376.2 276.0 125.3 187.9 224.1 243.7 148.0 134.3 206.0 158.9 149.2 10.8 223.2 506.3 174.1 80.5 152.8 244.0 136.8 120.3 124.4 204.3 35.3 9.1 127.6 313.3 100.3 265.2 54.4 102.2 170.7 208.1 9.4 197.7 120.3 165.8 6.0 16.1 245.4 159.8 85.4 174.9 259.6 119.5 204.1 195.1 86.3 98.6 213.7 208.1 212.0 168.9 208.1 318.0 735.5 282.1 139.7 141.7 393.0 RMI2 "BLAP18, C16orf75, MGC24665" ENSG00000175643 "RecQ mediated genome instability 2" Q96E14 16 11249619-11381662 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "DNA replication" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 36.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 123.8;Erythroid cells: 38.5;Extravillous trophoblasts: 34.1;Peritubular cells: 42.5;Spermatocytes: 36.6;Spermatogonia: 51.8;Syncytiotrophoblasts: 47.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 4.2" "Group enriched" "Detected in many" 6 "B-cells: 4.2;T-cells: 1.4" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA040995 Uncertain Supported "Nuclear speckles,Cytosol" NA Yes "Cluster 37: B-cells - Transcription" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nuclear speckles" Cytosol "HPA040995: AB_10795531" "unprognostic (2.76e-1)" "prognostic favorable (5.69e-5)" "unprognostic (1.17e-1)" "unprognostic (3.09e-3)" "unprognostic (1.69e-2)" "unprognostic (1.80e-3)" "prognostic unfavorable (2.77e-5)" "unprognostic (3.98e-1)" "unprognostic (1.16e-1)" "unprognostic (1.83e-1)" "unprognostic (3.44e-3)" "unprognostic (3.89e-1)" "unprognostic (2.18e-1)" "unprognostic (5.50e-2)" "unprognostic (3.68e-2)" "unprognostic (3.60e-3)" "unprognostic (1.03e-1)" 1.4 1.5 2.2 12.3 2.0 9.9 5.1 1.0 2.2 4.8 0.9 12.5 7.5 2.9 3.9 10.8 2.1 2.2 1.6 2.3 1.3 3.4 4.3 1.9 31.4 1.2 1.3 3.0 1.8 1.3 0.6 19.3 1.2 3.2 14.4 0.5 2.4 2.1 0.9 10.2 8.8 2.3 1.0 3.5 7.0 14.0 1.4 36.8 1.5 0.6 34.9 4.5 4.4 1.8 60.3 39.5 75.2 32.6 3.3 15.8 33.0 35.9 26.8 31.6 51.8 15.4 69.2 83.8 29.1 15.8 35.3 34.4 32.4 32.5 50.5 16.6 30.5 45.3 22.6 102.5 1.3 17.6 19.5 3.7 6.1 14.5 13.3 12.3 17.4 36.2 65.3 63.2 16.5 70.3 60.9 83.1 64.1 82.6 15.7 73.1 81.1 89.3 18.7 38.0 44.1 35.0 28.5 47.4 26.1 43.5 80.4 25.8 5.6 25.1 23.3 49.3 5.0 18.1 30.9 99.3 23.3 57.4 47.2 0.0 0.0 0.4 0.3 0.0 0.0 4.2 0.1 0.0 0.2 1.1 0.8 0.3 0.1 0.1 0.0 0.2 1.4 0.1 2.2 2.0 1.0 2.2 2.3 1.3 1.2 1.3 1.2 1.0 1.4 1.8 1.3 0.0 0.5 0.0 4.5 6.8 5.4 1.4 6.2 0.2 3.4 3.2 1.0 4.3 1.6 7.3 0.0 123.8 0.5 3.3 5.9 2.6 3.0 0.8 2.1 2.8 2.4 38.5 0.0 0.5 34.1 6.4 4.1 2.2 0.0 19.7 1.1 1.1 18.5 0.0 0.0 7.7 0.0 0.8 6.5 5.9 15.8 3.7 3.6 0.0 1.1 0.2 1.0 0.0 0.0 1.0 4.0 42.5 2.4 2.1 1.3 0.4 0.1 0.6 32.9 0.0 2.2 36.6 51.8 11.3 5.4 47.7 1.9 6.5 10.3 7.5 RREB1 HNT ENSG00000124782 "Ras responsive element binding protein 1" Q92766 6 7107597-7251980 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001756, HPA034843" Approved Supported "Nucleoli fibrillar center,Nuclear speckles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 1: K-562 - Erythropoiesis" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nuclear speckles" "Nucleoli fibrillar center" "HPA001756: AB_1856477, HPA034843: AB_2674357" "unprognostic (1.69e-1)" "unprognostic (3.16e-2)" "unprognostic (2.93e-1)" "unprognostic (5.05e-2)" "unprognostic (7.38e-2)" "unprognostic (1.23e-3)" "unprognostic (2.53e-1)" "unprognostic (1.32e-2)" "unprognostic (2.45e-2)" "unprognostic (6.51e-2)" "unprognostic (3.31e-2)" "unprognostic (1.16e-1)" "prognostic favorable (1.41e-4)" "unprognostic (1.21e-2)" "unprognostic (1.60e-1)" "unprognostic (9.54e-2)" "unprognostic (2.92e-1)" 10.9 12.1 4.3 7.8 3.6 31.6 10.8 4.4 2.2 10.2 12.5 10.8 11.9 7.8 5.6 26.2 8.7 6.4 8.3 2.7 4.2 8.2 18.3 9.1 6.5 9.1 6.6 9.8 18.1 12.2 6.3 8.1 6.5 8.1 9.8 5.7 15.0 6.2 16.6 16.2 13.1 6.2 5.4 10.7 10.7 11.6 7.6 9.2 12.0 7.9 7.9 7.9 14.2 5.5 13.1 12.3 10.3 11.9 9.5 6.3 40.1 5.2 7.3 6.2 7.6 20.3 10.0 6.6 10.9 9.9 6.9 9.3 14.7 16.5 5.9 9.2 11.3 24.8 9.6 23.5 13.1 15.0 18.5 10.5 12.7 9.3 13.8 4.2 7.5 15.2 44.6 0.1 6.5 16.5 8.8 35.2 4.9 10.6 10.0 13.1 12.4 10.4 9.0 25.1 2.8 2.6 12.4 16.0 11.1 15.3 12.3 31.0 13.0 11.4 7.1 8.8 6.4 4.1 4.7 9.0 3.3 11.4 9.3 5.5 2.7 6.6 1.5 2.1 1.3 2.2 1.0 1.0 1.7 1.0 1.6 1.3 2.0 3.3 2.4 5.7 0.5 1.7 4.3 3.6 4.4 2.2 2.7 4.2 9.1 6.6 6.5 5.4 7.6 5.5 39.3 25.6 28.7 44.4 19.0 31.5 22.4 30.1 27.9 0.9 27.0 16.9 24.2 31.5 31.4 36.8 70.9 25.8 31.9 62.7 7.9 14.7 46.2 35.5 24.7 22.5 31.8 31.1 3.9 16.3 32.8 16.3 30.1 63.0 10.1 20.7 30.7 70.4 33.4 0.0 0.7 35.7 14.2 66.1 54.9 9.0 19.9 42.1 23.2 78.7 32.6 9.5 13.4 2.0 0.9 22.3 36.3 19.2 27.7 37.1 34.5 16.8 23.9 27.5 52.6 25.5 15.2 13.7 17.4 48.9 34.7 45.8 15.7 27.4 45.0 54.3 RSBN1L "FLJ42526, FLJ45813, MGC71764" ENSG00000187257 "Round spermatid basic protein 1 like" Q6PCB5 7 77696459-77783022 "Cancer-related genes, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 349.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 60.6" "Lineage enriched" "Detected in all" 4 "granulocytes: 60.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020406, HPA020413" Approved Supported "Nuclear speckles,Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "Plasma membrane" "HPA020406: AB_1856488, HPA020413: AB_2253910" "unprognostic (2.02e-1)" "unprognostic (2.61e-2)" "unprognostic (2.41e-1)" "unprognostic (1.72e-1)" "unprognostic (1.34e-1)" "unprognostic (3.62e-2)" "unprognostic (2.43e-2)" "prognostic favorable (3.74e-4)" "unprognostic (1.27e-2)" "unprognostic (3.78e-2)" "unprognostic (1.25e-1)" "unprognostic (9.02e-2)" "unprognostic (7.30e-3)" "unprognostic (1.93e-1)" "unprognostic (1.46e-1)" "unprognostic (2.25e-3)" "unprognostic (1.53e-3)" 7.3 6.4 8.7 11.5 9.1 8.2 12.1 19.0 12.1 10.3 10.2 11.3 9.0 12.5 10.3 10.8 9.5 7.3 5.6 8.5 10.5 9.1 11.3 10.5 16.1 8.2 9.0 14.5 11.2 10.3 6.9 9.9 8.6 10.3 11.7 30.2 9.6 11.4 8.2 7.8 10.4 11.0 9.0 15.0 11.0 26.3 8.6 18.3 16.5 7.6 15.0 9.6 8.2 11.6 15.8 11.9 19.6 34.5 13.4 17.0 9.5 11.5 12.4 16.0 18.2 14.9 27.6 32.4 4.4 12.0 20.2 13.4 26.8 15.0 22.8 17.7 14.4 25.8 18.4 14.7 11.3 32.1 23.3 12.2 10.7 14.7 16.0 12.1 13.5 21.2 35.7 33.0 16.8 18.2 27.7 32.1 14.0 20.3 10.6 28.3 19.6 34.2 10.0 20.5 22.9 24.0 17.5 31.4 12.6 19.9 19.2 16.9 12.9 23.9 21.9 14.5 17.7 14.7 16.7 51.6 11.4 29.2 16.0 21.6 7.4 13.5 9.5 5.8 7.3 11.0 8.4 7.1 4.4 13.5 7.8 8.6 60.6 6.4 6.7 13.9 9.3 2.6 8.7 9.1 19.0 12.1 8.5 10.5 8.2 9.0 8.6 9.0 8.6 11.6 53.6 57.7 60.3 27.1 85.0 78.8 102.1 76.1 88.8 246.8 52.1 57.3 22.1 61.5 84.4 55.2 235.6 52.7 101.5 77.1 39.2 38.1 271.3 55.5 63.3 60.8 77.5 47.7 44.3 50.4 34.1 55.6 51.5 45.6 70.3 51.3 49.2 56.5 43.7 158.2 47.5 104.6 57.0 48.1 69.0 85.2 101.5 46.4 64.0 34.7 59.0 83.2 132.8 53.8 50.1 35.1 62.7 119.6 74.6 56.7 49.6 28.4 72.0 349.9 72.3 44.2 73.0 108.0 156.7 56.2 75.3 38.7 90.2 61.7 79.1 84.0 S100A11 S100C ENSG00000163191 "S100 calcium binding protein A11" P31949 1 152032506-152047907 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 4751.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 5473.4;Extravillous trophoblasts: 6093.0;Pancreatic endocrine cells: 6926.5;Urothelial cells: 6250.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 17820.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034320, HPA042745" Enhanced Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA 7900000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Nucleoplasm, Cytosol" "Nuclear speckles" "CAB034320: AB_2183487, HPA042745: AB_2678142" "unprognostic (1.85e-2)" "unprognostic (9.20e-2)" "unprognostic (1.99e-1)" "unprognostic (1.61e-1)" "unprognostic (3.12e-2)" "unprognostic (7.61e-2)" "prognostic unfavorable (3.64e-5)" "unprognostic (3.34e-2)" "unprognostic (8.48e-2)" "unprognostic (1.80e-2)" "unprognostic (1.28e-3)" "unprognostic (5.92e-2)" "prognostic unfavorable (3.24e-6)" "unprognostic (2.91e-1)" "unprognostic (2.75e-1)" "unprognostic (2.43e-3)" "unprognostic (8.86e-2)" 656.7 214.3 92.6 487.2 92.8 415.2 574.7 99.1 222.3 1070.5 106.8 303.0 181.6 297.7 675.4 4751.5 611.1 437.8 354.1 92.3 104.4 882.5 127.6 776.0 206.7 118.1 108.6 152.0 264.1 905.1 210.7 723.2 118.0 536.4 328.7 8.4 1247.1 544.1 91.0 894.7 239.5 468.3 110.2 713.7 482.6 68.9 124.1 303.5 325.3 150.9 959.9 1527.7 1771.1 126.8 1889.0 1483.7 70.5 542.1 1960.9 2451.3 1172.4 1796.3 2626.0 1439.7 1464.8 697.6 2066.0 2.5 1571.4 2355.4 1142.4 2595.4 73.7 3254.0 814.0 913.6 149.2 162.6 830.1 409.1 1511.3 149.6 1098.4 1867.2 3255.1 1577.8 1974.9 826.9 1116.1 0.3 340.9 352.1 2137.7 3058.8 19.8 694.0 513.9 4043.1 1491.9 2.5 757.1 1426.0 4361.1 3196.5 2.5 115.8 1367.7 1797.9 1255.3 1727.2 1378.9 1612.5 1584.8 757.0 533.1 1188.8 975.7 2.5 17.0 8.2 1713.0 490.9 915.2 7956.3 4682.6 7210.4 713.6 4560.1 939.4 354.9 1346.4 845.1 3020.5 252.7 391.5 437.0 17820.3 740.5 4871.8 1042.8 1269.9 5289.9 92.6 92.8 99.1 222.3 92.3 104.4 118.1 108.6 118.0 110.2 124.1 126.8 718.5 137.8 189.4 1.3 136.6 2210.3 3924.9 5473.4 1027.8 0.7 686.8 823.8 30.8 546.2 2673.9 2284.2 0.0 3257.0 384.0 421.7 1019.3 4344.5 277.6 1738.8 561.2 617.8 277.7 52.6 0.0 4330.2 6093.0 890.7 676.4 1503.0 437.6 251.1 372.6 11.6 3806.0 0.0 0.0 479.6 1485.2 1216.7 2054.0 634.0 320.9 1971.8 1243.3 15.9 2265.2 0.8 371.8 0.0 0.0 6926.5 690.2 258.4 153.8 4365.0 343.9 925.4 2674.2 2.4 210.4 536.2 1054.9 14.5 34.8 4207.9 2822.4 3753.1 470.4 334.8 500.2 6250.2 S100PBP "FLJ12903, S100PBPR" ENSG00000116497 "S100P binding protein" Q96BU1 1 32816767-32858875 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 78.8;Spermatocytes: 109.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027242, HPA027328" Approved Supported "Nuclear speckles" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nuclear speckles" "HPA027242: AB_2672174, HPA027328: AB_2672221" "unprognostic (4.29e-2)" "unprognostic (8.54e-2)" "unprognostic (3.54e-1)" "unprognostic (2.52e-3)" "unprognostic (2.44e-2)" "prognostic favorable (5.22e-5)" "prognostic unfavorable (1.26e-6)" "unprognostic (1.61e-1)" "unprognostic (2.52e-3)" "unprognostic (3.71e-1)" "unprognostic (6.79e-2)" "unprognostic (1.83e-2)" "prognostic unfavorable (9.03e-4)" "unprognostic (2.87e-1)" "unprognostic (1.06e-1)" "unprognostic (1.14e-1)" "unprognostic (1.48e-1)" 9.5 10.9 12.1 10.0 19.4 14.2 9.6 13.3 14.1 14.3 13.9 10.8 6.1 12.2 10.1 7.2 12.5 10.0 7.0 10.7 16.1 7.9 8.8 9.2 15.7 14.2 14.1 16.9 6.9 6.5 11.1 10.9 13.7 10.0 7.6 14.0 8.9 8.5 7.0 8.4 11.3 10.9 12.0 15.6 8.2 34.5 15.1 18.7 11.6 8.1 14.9 10.0 10.2 17.6 11.7 15.0 32.2 17.8 15.0 21.0 16.6 22.3 15.7 20.5 22.7 9.5 18.6 36.5 17.2 14.8 19.7 18.3 31.7 13.1 25.2 18.6 10.6 45.7 31.1 12.1 17.6 21.1 18.0 15.2 12.3 19.5 23.9 27.9 21.8 30.8 27.5 27.2 25.0 6.8 32.6 19.0 38.2 7.9 11.7 29.7 34.5 31.3 9.3 7.6 15.0 14.6 22.9 6.6 24.9 49.2 13.8 13.0 11.4 28.3 18.9 24.3 14.7 40.2 39.2 36.5 13.8 22.2 15.9 7.5 3.6 6.5 6.6 2.0 7.9 8.7 5.2 7.1 3.8 5.4 3.6 5.2 4.6 18.7 1.7 11.3 5.5 3.8 12.1 19.4 13.3 14.1 10.7 16.1 14.2 14.1 13.7 12.0 15.1 17.6 18.3 12.8 21.0 32.3 20.0 10.5 10.4 12.5 26.2 21.2 18.0 16.1 6.0 18.6 13.6 20.2 35.5 14.8 32.6 7.7 13.7 11.0 7.8 13.0 20.6 15.4 8.4 23.1 17.9 5.0 17.0 15.5 12.8 13.1 14.5 29.1 21.4 11.5 15.2 18.5 23.9 7.8 8.2 19.3 9.6 6.9 19.0 14.5 5.4 48.7 10.6 13.1 33.0 51.8 78.8 6.6 4.4 17.7 29.2 9.7 12.6 5.9 9.8 25.0 26.3 12.5 16.6 109.9 74.4 17.6 7.1 6.2 22.0 12.3 9.9 6.5 SAP130 FLJ12761 ENSG00000136715 "Sin3A associated protein 130" Q9H0E3 2 127941217-128028120 "Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 47.3" "Cell type enhanced" "Detected in many" "Early spermatids: 71.5;Late spermatids: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034664 Supported "Nuclear speckles" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nuclear speckles" "HPA034664: AB_10603238" "unprognostic (2.17e-2)" "unprognostic (1.96e-2)" "unprognostic (1.85e-1)" "unprognostic (1.33e-1)" "unprognostic (5.45e-2)" "unprognostic (1.65e-1)" "prognostic unfavorable (7.89e-4)" "unprognostic (2.75e-1)" "unprognostic (1.30e-2)" "unprognostic (1.43e-1)" "unprognostic (3.92e-2)" "unprognostic (6.77e-2)" "unprognostic (3.75e-2)" "unprognostic (5.26e-2)" "unprognostic (4.41e-1)" "unprognostic (2.13e-1)" "unprognostic (1.13e-1)" 9.1 8.6 8.8 8.7 8.5 21.7 8.2 8.5 10.2 10.5 5.1 10.3 8.3 10.4 9.2 10.4 9.6 7.2 8.5 8.1 10.8 7.2 8.3 8.0 10.0 6.4 7.9 11.2 8.7 12.4 14.5 9.0 7.1 8.7 9.7 8.6 9.1 7.9 11.9 12.9 9.8 10.2 6.1 8.5 9.7 47.3 8.0 14.8 8.8 13.0 12.6 9.5 10.3 8.8 35.3 18.9 35.3 28.6 22.9 15.7 38.5 22.0 21.4 33.4 26.2 45.1 14.4 29.4 19.3 25.0 17.4 24.0 39.3 22.7 34.5 16.3 25.2 29.2 16.7 35.9 27.5 25.5 22.2 14.8 16.7 44.1 27.5 17.6 27.0 24.4 35.9 21.1 28.2 39.3 35.6 20.0 36.6 20.7 21.1 24.3 29.0 19.6 17.9 30.7 18.5 22.3 23.2 21.7 13.6 22.1 16.4 17.3 23.2 32.1 34.5 30.1 23.6 29.3 31.2 34.3 26.4 17.0 21.0 2.3 4.2 4.6 5.3 2.7 4.0 2.0 3.8 3.5 3.4 5.0 2.7 3.1 14.0 3.6 8.6 6.2 2.7 3.8 8.8 8.5 8.5 10.2 8.1 10.8 6.4 7.9 7.1 6.1 8.0 8.8 5.4 0.0 10.9 29.0 7.9 7.9 2.3 3.2 5.7 5.2 6.5 5.3 15.2 2.8 3.1 1.8 8.4 11.9 9.4 13.1 0.0 4.9 71.5 4.6 8.6 6.2 6.7 11.6 25.4 4.7 12.8 5.2 8.6 8.7 1.3 5.3 5.3 5.8 7.8 8.4 28.9 7.0 4.1 8.4 6.3 44.2 8.4 7.0 5.4 16.9 4.9 5.0 6.2 26.2 31.0 6.1 7.8 8.2 13.2 4.9 6.5 3.4 4.0 5.8 6.6 4.4 5.5 31.0 17.9 9.2 10.4 19.3 7.6 3.7 7.8 4.3 SARNP "CIP29, Hcc-1, THO1" ENSG00000205323 "SAP domain containing ribonucleoprotein" P82979 12 55752463-55817724 "Plasma proteins, Predicted intracellular proteins" "mRNA transport, Transcription, Transcription regulation, Translation regulation, Transport" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030902, HPA030903" Supported Supported "Nuclear speckles" NA NA 150000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nuclear speckles" "HPA030902: AB_10669872, HPA030903: AB_10964180" "unprognostic (1.83e-2)" "unprognostic (1.58e-2)" "unprognostic (2.22e-1)" "unprognostic (2.50e-1)" "unprognostic (3.01e-2)" "unprognostic (2.10e-1)" "unprognostic (2.36e-4)" "unprognostic (2.02e-2)" "unprognostic (4.29e-3)" "unprognostic (1.21e-2)" "unprognostic (5.03e-2)" "unprognostic (6.48e-2)" "unprognostic (2.31e-6)" "unprognostic (8.50e-2)" "unprognostic (1.31e-1)" "unprognostic (5.29e-3)" "unprognostic (1.19e-1)" 48.0 59.1 52.9 45.8 53.7 88.8 58.0 56.4 88.2 52.6 55.0 53.7 31.1 48.2 57.2 61.9 42.3 34.8 81.5 53.4 60.8 62.5 49.4 46.4 67.2 54.8 56.8 48.5 31.6 45.7 43.7 55.1 55.3 48.0 53.6 31.6 39.4 47.7 98.9 43.3 38.5 53.4 53.5 47.9 44.1 55.4 55.8 83.0 41.6 84.0 84.5 59.8 48.3 56.2 118.8 106.6 251.5 107.9 114.9 162.9 119.7 160.5 126.2 196.7 163.6 151.4 129.1 191.3 108.7 131.8 77.2 66.5 223.7 158.2 209.8 151.2 140.5 192.5 181.6 132.9 166.9 162.0 142.4 121.1 115.7 129.0 99.7 206.0 210.4 169.1 141.3 137.9 198.0 100.5 204.1 257.8 221.4 107.0 97.8 186.5 131.6 159.3 265.9 133.0 108.2 87.8 138.1 88.1 144.8 143.3 134.1 216.3 146.1 79.0 79.3 101.3 128.3 87.0 122.8 258.5 94.9 163.8 101.9 246.1 137.9 218.7 110.5 156.2 101.1 125.3 115.8 119.0 153.7 114.0 91.7 103.0 107.2 134.2 138.8 146.8 170.6 153.9 52.9 53.7 56.4 88.2 53.4 60.8 54.8 56.8 55.3 53.5 55.8 56.2 14.7 32.1 35.6 27.7 26.6 25.2 24.5 24.0 46.1 11.2 12.9 9.9 0.2 10.0 41.0 22.0 16.7 16.1 17.9 11.8 25.4 28.8 16.3 9.1 8.8 16.5 14.9 34.1 32.8 29.8 19.8 30.5 33.6 11.4 27.8 8.9 8.9 7.4 14.6 8.4 33.8 13.3 24.4 19.2 36.3 35.9 18.0 25.1 21.4 27.2 32.4 10.6 16.5 37.7 46.6 32.1 13.1 17.3 37.0 14.8 14.8 19.1 45.2 10.0 6.6 12.6 23.3 36.4 32.8 50.9 26.6 16.8 29.9 12.2 11.5 20.4 SCAPER "Zfp291, ZNF291" ENSG00000140386 "S-phase cyclin A associated protein in the ER" Q9BY12 15 76347904-76905444 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Mental retardation, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 55.4" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 252.3;Oligodendrocytes: 251.5;Rod photoreceptor cells: 710.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046253, HPA048077" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA No "Cluster 11: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 16: U-266 - Nucleosome" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Nuclear speckles" Cytosol "HPA046253: AB_2679600, HPA048077: " "unprognostic (3.67e-1)" "unprognostic (8.60e-2)" "unprognostic (6.08e-2)" "unprognostic (8.37e-2)" "unprognostic (1.48e-1)" "unprognostic (1.63e-1)" "unprognostic (1.37e-1)" "unprognostic (2.76e-2)" "unprognostic (4.94e-2)" "unprognostic (3.74e-2)" "unprognostic (5.40e-2)" "unprognostic (1.02e-1)" "prognostic favorable (2.69e-9)" "unprognostic (2.14e-1)" "unprognostic (3.79e-1)" "unprognostic (1.86e-1)" "unprognostic (2.89e-3)" 5.5 7.9 9.7 4.0 12.2 7.4 6.9 18.2 10.4 6.2 6.5 6.0 6.5 7.4 7.7 8.9 6.4 5.3 13.8 9.0 12.8 9.0 7.5 6.3 4.7 11.5 10.5 12.1 8.3 14.5 8.2 6.5 11.3 7.0 4.4 55.4 7.9 6.2 13.6 6.9 6.3 6.3 9.2 5.9 6.1 21.0 10.7 8.6 12.2 12.0 6.0 5.0 6.5 16.3 6.3 5.8 7.8 4.5 3.9 7.0 6.5 8.3 5.9 3.8 5.4 6.1 5.0 6.3 7.2 2.8 10.0 6.7 18.5 3.5 5.7 14.7 9.1 3.3 6.8 3.0 4.9 9.0 7.6 5.9 6.0 4.5 7.3 8.2 5.2 12.6 4.8 17.5 6.6 2.6 8.8 2.7 2.3 5.5 3.3 7.9 12.4 2.2 3.5 6.3 18.4 8.9 11.2 3.9 9.0 9.4 5.8 7.3 6.3 8.7 8.1 4.1 7.4 10.5 23.7 8.9 5.1 11.1 5.9 40.8 6.3 17.4 11.4 3.5 13.1 16.3 11.5 10.3 3.6 17.0 18.8 12.1 10.7 17.1 4.2 9.3 9.7 4.2 9.7 12.2 18.2 10.4 9.0 12.8 11.5 10.5 11.3 9.2 10.7 16.3 28.5 99.3 61.5 190.7 33.2 20.6 28.9 10.6 18.8 91.5 13.9 15.5 191.3 12.8 27.4 12.9 252.3 33.8 26.6 17.1 1.9 14.6 59.1 10.6 13.8 23.5 16.2 1.7 151.5 6.0 11.8 22.1 17.3 18.4 22.1 41.9 21.8 9.3 14.3 77.4 201.8 9.0 6.1 13.6 11.3 24.9 20.5 14.4 10.6 135.9 12.8 51.3 34.0 203.1 251.5 6.5 11.4 19.2 28.6 15.9 72.6 7.8 12.3 710.6 19.7 39.1 23.5 143.9 68.9 15.1 18.8 52.0 30.5 26.7 13.4 19.7 SETD1A "KIAA0339, KMT2F, Set1" ENSG00000099381 "SET domain containing 1A, histone lysine methyltransferase" O15047 16 30957754-30984664 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Methyltransferase, RNA-binding, Transferase" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020646, HPA058376" Enhanced Supported "Nuclear speckles" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nuclear speckles" "HPA020646: AB_1856752, HPA058376: AB_2683695" "unprognostic (8.62e-2)" "unprognostic (1.93e-2)" "unprognostic (3.96e-2)" "unprognostic (1.53e-1)" "unprognostic (1.85e-1)" "unprognostic (1.40e-2)" "prognostic unfavorable (8.47e-4)" "unprognostic (5.01e-2)" "unprognostic (1.54e-1)" "unprognostic (3.18e-1)" "unprognostic (5.77e-2)" "unprognostic (1.72e-1)" "unprognostic (1.55e-1)" "unprognostic (1.27e-1)" "unprognostic (2.12e-1)" "unprognostic (1.70e-2)" "unprognostic (1.94e-1)" 10.2 10.0 6.0 7.3 5.5 20.1 10.0 8.4 8.3 11.0 3.0 13.0 6.6 13.0 2.8 9.0 10.5 4.1 8.5 5.5 5.5 8.4 10.4 8.2 8.6 5.6 5.4 12.4 10.6 8.0 11.9 5.0 5.4 10.2 3.3 3.1 9.3 6.1 15.1 12.3 10.5 6.3 4.1 11.8 10.0 20.8 6.0 10.0 11.8 7.1 5.1 10.2 9.3 6.9 13.1 24.4 15.9 19.4 8.7 6.3 18.0 13.6 10.6 11.9 10.1 20.2 12.8 34.2 15.2 13.0 12.0 16.4 15.0 14.6 9.3 18.5 56.1 16.0 47.1 23.2 8.9 26.6 26.2 11.0 11.3 17.1 10.8 9.2 9.3 19.5 32.3 19.0 6.4 27.2 32.3 27.7 23.4 9.0 15.4 48.7 15.9 21.9 7.6 13.9 17.6 18.1 18.7 15.1 10.8 8.7 16.2 22.1 12.8 17.7 17.1 11.6 14.9 28.0 36.2 32.4 14.3 22.9 13.5 0.0 0.1 0.6 0.2 0.3 0.3 0.0 0.2 0.2 0.1 0.5 0.1 0.2 0.0 0.2 0.1 0.6 0.1 0.2 6.0 5.5 8.4 8.3 5.5 5.5 5.6 5.4 5.4 4.1 6.0 6.9 7.8 3.2 9.2 9.1 8.8 15.7 5.1 3.8 15.4 8.1 9.5 8.3 3.9 5.7 4.0 7.3 6.2 4.6 11.4 6.8 0.0 4.2 3.1 6.1 8.2 9.9 10.3 6.7 6.4 4.2 3.7 7.8 6.1 8.6 3.8 9.5 7.5 9.1 6.5 13.5 6.1 7.9 2.0 4.7 7.1 2.9 9.9 5.5 8.8 6.5 4.7 4.8 7.2 2.5 5.7 5.4 4.8 11.7 7.9 8.3 5.1 2.8 4.0 5.2 6.6 10.8 7.8 17.5 23.3 15.7 12.9 2.9 8.6 10.3 6.9 4.8 SF3A3 "PRP9, PRPF9, SAP61, SF3a60" ENSG00000183431 "Splicing factor 3a subunit 3" Q12874 1 37956975-37990075 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032054, HPA032055" Supported Supported "Nucleoplasm,Nuclear speckles" NA NA 57000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" Nucleoplasm "HPA032054: AB_10602184, HPA032055: AB_2674130" "unprognostic (1.56e-1)" "unprognostic (1.21e-1)" "unprognostic (7.08e-3)" "unprognostic (6.19e-3)" "unprognostic (1.06e-1)" "unprognostic (5.68e-2)" "prognostic unfavorable (2.11e-8)" "unprognostic (1.34e-1)" "unprognostic (2.74e-2)" "unprognostic (5.74e-3)" "unprognostic (9.18e-2)" "unprognostic (4.79e-1)" "unprognostic (1.23e-2)" "unprognostic (2.52e-3)" "unprognostic (8.39e-2)" "unprognostic (2.24e-1)" "unprognostic (3.68e-2)" 24.6 23.4 22.3 29.2 22.6 57.9 31.7 24.1 29.0 25.6 23.2 25.1 20.4 30.5 33.7 23.3 27.5 19.1 18.6 22.0 22.8 26.0 27.4 22.9 39.0 22.6 22.6 32.1 20.3 30.6 16.2 25.4 22.9 24.9 30.0 29.9 23.5 28.8 49.6 29.2 21.4 31.7 22.3 27.4 20.0 27.5 23.4 43.4 26.9 27.4 44.6 28.1 18.8 24.0 84.4 57.0 108.1 90.8 63.3 57.7 129.6 82.2 69.1 131.9 106.4 97.2 84.4 165.8 68.1 73.6 51.6 71.5 136.7 108.6 162.3 74.9 125.7 206.3 92.3 86.7 57.9 261.1 93.5 54.9 75.4 135.5 88.4 58.6 89.9 112.6 176.1 60.0 95.2 53.2 131.4 123.0 268.0 80.4 89.9 156.8 197.0 110.7 59.4 83.5 95.8 69.4 104.2 47.1 83.9 95.1 54.0 90.3 82.0 70.3 79.6 64.9 157.2 57.6 89.5 166.4 65.6 215.6 92.1 37.2 41.3 28.4 56.1 53.3 55.0 54.9 65.3 56.7 53.1 68.9 69.4 58.9 4.6 56.2 61.8 32.5 75.5 61.7 22.3 22.6 24.1 29.0 22.0 22.8 22.6 22.6 22.9 22.3 23.4 24.0 37.3 51.3 35.0 11.4 42.2 47.3 38.6 46.6 55.2 37.0 21.3 27.7 22.7 20.0 42.3 22.0 22.9 59.1 40.7 12.1 39.2 44.4 37.9 23.7 42.4 35.8 15.6 53.6 15.7 38.1 69.2 41.6 15.3 25.3 42.4 43.0 25.0 23.6 51.5 26.9 14.9 23.9 34.6 28.0 39.8 14.0 39.7 34.2 39.2 6.5 82.9 45.6 44.3 11.1 11.5 35.4 13.1 54.2 41.5 28.5 19.0 29.2 27.8 38.6 39.5 47.2 68.3 120.8 55.2 36.5 41.8 33.0 42.9 53.5 31.4 24.0 SFMBT2 KIAA1617 ENSG00000198879 "Scm like with four mbt domains 2" Q5VUG0 10 7158624-7411486 "Predicted intracellular proteins" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 27.7" "Cell type enriched" "Detected in many" 4 "Microglial cells: 618.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 4.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 23.0;REH: 21.0;RPMI-8226: 20.2;SH-SY5Y: 16.6;THP-1: 25.0;U-937: 16.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA035447, HPA035448, HPA070388" Uncertain Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 43: THP-1 - Innate immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Nuclear speckles" "HPA035447: AB_2674628, HPA035448: AB_10669904, HPA070388: " "unprognostic (4.36e-2)" "unprognostic (2.29e-2)" "unprognostic (4.36e-2)" "unprognostic (1.42e-3)" "unprognostic (3.23e-2)" "unprognostic (2.05e-3)" "unprognostic (4.65e-1)" "unprognostic (4.56e-1)" "unprognostic (1.03e-1)" "unprognostic (6.51e-2)" "unprognostic (5.57e-2)" "unprognostic (1.38e-1)" "unprognostic (2.41e-2)" "unprognostic (1.26e-1)" "unprognostic (9.17e-3)" "unprognostic (5.37e-3)" "unprognostic (7.29e-2)" 3.8 4.1 13.0 5.9 13.1 6.6 5.5 10.2 9.8 3.4 5.1 2.8 2.0 4.0 3.7 1.1 4.0 3.5 4.0 7.5 17.6 3.0 1.3 4.7 7.3 20.4 15.0 9.1 1.3 5.7 6.4 3.4 17.1 6.6 3.2 18.0 2.3 3.1 4.2 1.7 4.0 3.3 12.7 9.0 3.1 1.8 27.7 4.5 6.8 2.6 5.8 4.1 4.2 19.0 0.0 4.0 0.3 0.0 0.0 0.0 4.9 0.1 0.0 0.0 0.0 0.0 1.1 7.6 0.0 0.0 0.0 1.9 7.6 0.0 0.0 0.4 7.9 0.0 13.0 0.0 0.7 8.0 1.1 1.1 0.4 0.0 0.3 0.0 0.1 10.0 11.5 23.0 0.0 3.5 7.0 14.3 1.6 0.0 0.0 21.0 2.2 20.2 0.0 0.8 2.0 16.6 0.0 0.1 0.0 2.1 1.3 25.0 0.0 0.0 2.6 0.4 0.2 10.1 13.3 0.0 1.1 16.5 0.3 0.1 0.2 1.1 0.7 2.3 0.4 0.0 0.2 0.5 0.4 0.0 1.0 0.6 0.1 0.9 4.6 3.1 0.0 0.2 13.0 13.1 10.2 9.8 7.5 17.6 20.4 15.0 17.1 12.7 27.7 19.0 8.2 0.0 5.2 148.2 10.2 1.5 1.5 0.0 1.2 8.1 9.3 8.6 9.7 1.5 0.6 0.0 81.3 7.7 22.1 0.1 0.0 0.4 0.2 0.8 15.8 10.1 4.2 6.1 77.3 0.2 2.5 4.2 2.0 3.5 4.5 7.1 5.7 1.1 15.5 0.0 103.9 0.0 0.0 15.7 9.9 0.8 5.0 26.3 5.4 618.3 11.4 12.4 15.5 26.2 113.7 0.1 0.0 2.2 25.8 11.4 0.0 0.3 0.7 34.1 0.0 4.4 2.6 0.3 3.9 0.2 1.3 4.4 25.8 2.5 0.2 0.6 SIRT7 ENSG00000187531 "Sirtuin 7" Q9NRC8 17 81911939-81921323 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Chromatin regulator, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 152.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 22.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027284, HPA028246, CAB037261, HPA053669" Approved Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nuclear speckles" "CAB037261: AB_1079989, HPA027284: , HPA028246: , HPA053669: AB_2682224" "unprognostic (8.15e-3)" "unprognostic (3.24e-2)" "unprognostic (3.26e-2)" "unprognostic (2.41e-2)" "unprognostic (1.46e-1)" "unprognostic (3.36e-2)" "prognostic unfavorable (1.97e-5)" "unprognostic (3.03e-1)" "unprognostic (2.10e-1)" "unprognostic (2.46e-2)" "unprognostic (2.79e-1)" "unprognostic (1.71e-2)" "prognostic unfavorable (1.69e-7)" "unprognostic (4.34e-3)" "unprognostic (1.20e-1)" "unprognostic (4.77e-2)" "unprognostic (2.16e-2)" 8.8 8.0 6.8 7.4 7.3 23.2 8.6 7.5 8.6 12.5 7.4 17.3 12.9 7.0 1.9 42.1 8.0 5.4 6.4 6.9 6.7 11.5 14.2 9.6 11.8 7.6 7.0 6.0 12.8 5.4 6.9 4.2 7.4 9.8 5.8 0.6 14.1 3.7 6.2 22.4 17.1 3.6 7.0 18.7 17.9 13.3 7.6 9.4 7.9 3.7 7.2 10.8 18.0 7.6 26.5 21.7 2.8 9.5 6.9 6.4 17.0 13.1 10.8 15.1 14.1 18.7 20.7 11.8 9.9 7.3 9.6 18.8 10.5 8.1 4.9 10.2 22.9 10.4 10.7 29.7 20.4 13.6 20.5 6.5 25.0 14.5 11.9 6.4 11.3 6.5 11.3 5.8 7.2 20.9 14.6 19.5 6.8 40.6 22.3 9.7 5.5 11.1 14.7 17.4 11.1 14.6 15.0 35.9 17.7 5.0 15.1 32.1 9.0 6.8 14.9 12.9 24.2 9.5 3.2 9.0 16.6 18.4 11.3 4.5 2.6 22.2 2.8 3.8 0.9 4.5 2.1 2.3 1.4 7.0 2.0 0.7 4.4 1.8 3.3 2.1 1.2 1.5 6.8 7.3 7.5 8.6 6.9 6.7 7.6 7.0 7.4 7.0 7.6 7.6 15.2 12.8 12.2 12.4 41.4 38.0 25.8 21.1 28.5 23.4 27.4 19.0 4.4 18.6 18.7 18.4 56.3 31.1 62.8 99.0 9.8 22.4 21.8 28.8 14.0 15.4 20.4 16.0 14.3 13.6 33.2 12.4 152.9 37.0 11.4 20.1 15.0 16.0 26.1 30.3 10.6 34.6 28.5 26.4 33.5 14.1 14.3 29.4 24.9 5.6 47.3 14.7 71.1 6.6 13.8 52.7 74.5 10.1 33.2 29.1 74.7 16.0 29.6 39.1 0.0 12.5 15.5 41.3 37.4 52.4 55.5 49.3 50.8 17.9 44.6 53.9 SLU7 9G8 ENSG00000164609 "SLU7 homolog, splicing factor" O95391 5 160401641-160421711 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035907, HPA058120" Uncertain Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 6: Brain - Smell perception" "Cluster 44: HDLM-2 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Nuclear speckles" "HPA035907: AB_10671717, HPA058120: AB_2683612" "unprognostic (3.70e-2)" "unprognostic (7.18e-2)" "unprognostic (1.86e-2)" "unprognostic (9.96e-3)" "unprognostic (8.01e-2)" "unprognostic (3.52e-1)" "unprognostic (3.38e-3)" "unprognostic (3.76e-2)" "unprognostic (2.22e-2)" "unprognostic (2.42e-1)" "unprognostic (1.93e-1)" "unprognostic (7.69e-2)" "prognostic favorable (1.98e-4)" "unprognostic (2.65e-1)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" "unprognostic (1.25e-1)" 22.1 23.2 26.2 19.5 27.2 48.6 27.4 27.7 46.6 21.1 22.3 20.8 17.0 19.9 25.9 21.9 18.0 18.7 25.8 28.3 26.7 24.4 24.4 23.3 27.3 25.6 27.2 21.3 16.4 24.6 10.9 21.1 26.0 21.2 20.9 29.4 24.7 19.7 32.6 22.6 21.5 18.2 24.6 27.9 23.4 27.2 26.6 30.4 32.2 33.0 31.3 21.5 12.1 28.9 24.5 29.6 26.0 36.2 33.4 35.1 33.1 33.9 49.3 35.9 43.8 40.1 29.1 39.5 34.2 36.6 36.9 27.0 22.9 37.7 45.2 65.1 33.0 29.4 39.0 26.2 33.7 49.8 34.9 38.1 34.3 33.8 38.1 37.7 25.7 35.3 26.7 36.0 33.2 21.5 24.7 32.1 18.6 25.2 26.5 21.4 53.4 40.4 31.6 37.8 30.9 42.7 40.1 35.6 62.2 21.6 47.7 46.4 32.7 34.5 18.2 26.1 36.3 40.1 48.8 34.9 51.2 33.1 33.4 49.9 22.2 39.2 26.7 24.9 25.5 30.0 25.2 27.2 20.2 26.1 27.2 26.7 54.2 33.9 36.5 21.6 29.4 22.8 26.2 27.2 27.7 46.6 28.3 26.7 25.6 27.2 26.0 24.6 26.6 28.9 42.7 67.3 67.8 9.8 53.7 44.7 39.9 55.5 24.5 70.2 25.7 26.3 71.4 24.3 57.1 25.8 25.0 38.1 70.9 34.1 50.9 52.2 126.2 43.0 41.6 44.1 39.5 68.8 19.8 55.8 39.7 43.0 17.9 51.3 46.3 34.7 35.3 24.6 38.4 57.2 18.3 34.7 54.9 47.3 57.3 34.3 47.8 46.9 65.8 20.6 65.8 61.6 64.9 9.0 15.2 50.5 45.3 47.4 33.1 40.0 39.8 39.5 62.0 49.4 46.0 49.6 50.1 88.9 54.6 27.4 41.5 94.1 52.0 41.9 27.8 52.5 SMC4 "CAP-C, hCAP-C, SMC4L1" ENSG00000113810 "Structural maintenance of chromosomes 4" Q9NTJ3 3 160399274-160434954 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 60.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 305.8;Spermatocytes: 339.8;Spermatogonia: 239.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "basophil: 74.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029449, CAB055509" Approved Supported "Nuclear speckles,Cytosol" NA Yes 25000 "Cluster 18: Basophils - Vesicular transport" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear speckles, Cytosol" "CAB055509: , HPA029449: AB_10603891" "unprognostic (2.63e-1)" "unprognostic (1.01e-1)" "unprognostic (2.45e-2)" "prognostic unfavorable (7.63e-4)" "unprognostic (2.22e-1)" "unprognostic (1.28e-2)" "prognostic unfavorable (2.94e-4)" "unprognostic (9.54e-2)" "unprognostic (2.18e-2)" "unprognostic (5.47e-2)" "prognostic unfavorable (4.20e-5)" "prognostic unfavorable (9.00e-4)" "prognostic unfavorable (8.05e-7)" "unprognostic (3.03e-2)" "unprognostic (4.46e-1)" "unprognostic (1.06e-1)" "unprognostic (4.98e-2)" 6.8 6.5 1.0 21.2 2.0 36.3 6.8 1.2 1.7 6.3 1.5 13.2 14.0 7.4 2.3 23.5 4.5 7.6 7.3 0.9 1.9 5.9 7.8 11.8 37.1 1.7 1.4 5.9 7.8 3.8 2.0 16.2 1.6 5.8 14.9 7.7 4.6 5.0 3.6 11.0 15.4 10.1 1.3 14.7 11.8 32.5 1.9 60.6 9.0 6.8 31.6 9.6 4.3 3.2 386.3 72.8 155.0 73.0 31.5 30.9 72.1 181.2 88.8 206.0 176.8 94.4 209.7 236.6 101.9 81.1 140.0 212.5 183.0 95.0 332.4 297.9 113.8 234.7 123.3 33.6 17.3 158.3 182.6 14.6 13.3 114.4 96.5 78.5 94.8 103.2 130.3 272.2 133.9 78.3 183.2 44.4 91.8 106.7 149.3 180.1 238.8 177.3 43.4 54.8 93.7 94.0 141.4 135.1 65.5 76.6 156.9 128.6 84.8 132.2 105.2 119.9 349.8 181.1 192.2 412.0 96.7 166.9 151.9 74.4 6.0 23.6 11.5 8.9 11.4 17.2 18.2 14.3 6.6 15.0 11.4 10.2 10.8 15.3 15.9 11.7 30.3 9.5 1.0 2.0 1.2 1.7 0.9 1.9 1.7 1.4 1.6 1.3 1.9 3.2 24.6 105.8 174.0 3.9 43.7 40.8 18.2 33.1 30.7 14.9 21.5 21.0 41.3 25.8 35.0 35.0 8.4 74.6 54.4 41.4 3.9 20.9 48.6 35.2 27.0 44.8 30.1 305.8 3.5 14.7 138.1 50.7 32.6 36.1 79.1 77.3 38.2 20.4 61.3 0.0 2.9 44.5 24.4 29.7 43.5 28.3 25.1 36.4 17.8 17.8 39.3 9.3 46.4 3.5 30.1 13.5 26.5 48.2 95.9 14.1 25.9 8.6 25.4 25.8 131.5 21.7 73.2 339.8 239.4 58.1 35.7 34.1 58.4 34.6 69.7 19.1 SMC5 "KIAA0594, SMC5L1" ENSG00000198887 "Structural maintenance of chromosomes 5" Q8IY18 9 70258978-70354873 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054900 Supported Supported "Nuclear speckles" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "HPA054900: AB_2682634" "unprognostic (2.55e-1)" "unprognostic (1.82e-1)" "unprognostic (1.24e-2)" "unprognostic (1.40e-1)" "unprognostic (2.72e-1)" "unprognostic (8.04e-3)" "unprognostic (2.15e-2)" "unprognostic (1.20e-1)" "unprognostic (3.80e-2)" "unprognostic (2.23e-1)" "unprognostic (3.36e-2)" "unprognostic (7.30e-2)" "unprognostic (1.71e-2)" "unprognostic (2.73e-2)" "unprognostic (2.54e-1)" "unprognostic (1.62e-1)" "unprognostic (1.80e-1)" 10.2 7.7 4.3 15.0 4.8 26.0 16.6 10.4 5.0 12.2 9.0 15.0 13.5 15.2 12.8 10.8 12.3 12.9 9.9 4.2 6.1 8.0 14.8 12.8 18.5 5.2 5.7 25.2 19.4 10.4 9.6 14.8 5.7 11.4 16.9 8.3 17.1 8.7 13.8 9.0 13.9 10.7 4.2 12.0 14.5 13.5 4.9 18.2 14.3 8.2 16.1 16.4 11.3 7.8 43.9 10.8 26.6 16.2 15.1 28.3 20.9 29.8 25.8 15.9 17.3 4.1 23.3 43.7 9.5 22.5 13.9 39.3 28.9 19.8 31.7 19.9 10.3 25.5 18.3 13.1 19.2 41.8 25.3 19.9 13.5 21.5 24.5 25.4 16.9 25.8 19.1 17.1 29.9 6.7 55.4 14.7 20.4 33.5 14.9 32.4 43.6 13.7 16.1 21.3 18.9 14.2 29.5 18.7 8.3 19.2 11.2 17.6 18.6 21.3 22.4 29.2 41.2 20.9 29.9 29.9 17.9 21.6 25.9 14.1 5.6 10.4 8.5 6.3 8.0 8.4 7.3 8.1 4.6 8.2 8.0 7.4 3.7 8.1 7.6 8.7 8.4 4.0 4.3 4.8 10.4 5.0 4.2 6.1 5.2 5.7 5.7 4.2 4.9 7.8 48.9 57.7 70.3 61.7 54.6 45.6 102.0 30.3 59.7 26.8 39.2 34.0 34.6 41.5 62.0 20.2 29.2 32.1 65.2 38.8 9.8 61.3 47.9 65.3 58.9 37.6 28.1 29.0 72.2 54.8 37.5 62.1 40.8 89.1 51.8 52.5 16.1 25.9 16.4 38.7 66.4 34.8 20.3 22.9 30.8 15.9 53.4 37.9 24.9 74.0 65.4 17.2 54.6 85.5 94.6 68.3 37.9 59.5 40.6 105.5 23.6 11.7 51.0 35.7 26.3 66.2 52.2 80.0 55.0 52.5 41.9 35.6 56.7 58.4 45.0 105.8 SMURF2 ENSG00000108854 "SMAD specific E3 ubiquitin protein ligase 2" Q9HAU4 17 64542282-64662307 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BJ: 221.1;HBF TERT88: 157.4;LHCN-M2: 164.1;TIME: 207.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071508 Enhanced Supported "Nuclear speckles" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nuclear speckles" "HPA071508: AB_2686406" "unprognostic (1.21e-1)" "unprognostic (2.07e-2)" "unprognostic (1.59e-2)" "unprognostic (3.24e-1)" "unprognostic (6.19e-2)" "unprognostic (7.33e-2)" "unprognostic (2.67e-2)" "unprognostic (1.50e-1)" "unprognostic (7.94e-2)" "unprognostic (1.09e-2)" "unprognostic (5.46e-3)" "unprognostic (2.54e-1)" "unprognostic (5.55e-2)" "unprognostic (1.98e-2)" "unprognostic (7.82e-2)" "unprognostic (2.20e-2)" "unprognostic (1.41e-1)" 6.8 4.3 3.3 6.2 3.9 5.9 5.2 5.3 3.4 7.3 3.4 5.3 6.9 5.9 2.3 4.4 5.8 7.1 4.1 3.1 3.3 7.0 3.8 10.5 5.0 4.6 2.7 4.8 6.5 6.3 3.4 13.3 2.8 7.4 4.8 12.5 6.2 5.2 3.0 5.0 10.1 6.1 3.2 5.4 7.8 13.0 3.6 7.8 8.3 6.2 6.5 7.5 3.2 3.8 67.0 17.8 15.3 9.1 11.0 41.5 7.6 221.1 103.2 88.2 73.4 10.4 45.5 8.6 14.5 38.8 29.9 15.2 16.0 37.2 157.4 4.3 12.9 9.1 10.9 11.8 12.0 12.2 5.5 11.8 16.1 109.5 48.5 52.7 97.0 11.9 13.0 7.5 164.1 13.2 28.3 4.8 9.9 8.8 23.8 6.1 38.4 5.2 20.1 11.1 16.0 17.9 14.4 5.8 10.0 24.6 11.7 8.4 207.6 93.8 44.4 39.2 139.6 10.4 11.7 13.9 23.7 7.3 28.4 1.0 0.6 1.4 1.0 0.4 1.1 0.7 0.8 1.1 0.7 0.9 0.9 0.9 1.4 2.7 0.3 0.6 0.2 0.5 3.3 3.9 5.3 3.4 3.1 3.3 4.6 2.7 2.8 3.2 3.6 3.8 40.2 32.1 26.0 96.3 18.6 43.8 30.8 10.0 25.0 26.4 23.3 18.7 10.3 7.2 16.1 9.2 43.8 13.2 35.4 13.8 9.8 18.1 29.0 29.0 37.2 39.3 17.9 2.5 46.1 10.0 3.6 28.1 12.2 39.7 13.3 21.4 38.2 5.1 13.6 26.9 40.9 11.2 10.2 17.3 25.5 9.2 12.5 22.8 21.4 101.2 13.2 21.4 20.6 101.0 52.8 26.5 24.7 12.0 18.0 25.2 28.0 9.6 14.4 46.7 0.0 37.4 23.3 37.1 21.3 13.7 39.8 7.3 33.5 16.2 13.8 24.6 SNRNP40 "HPRP8BP, PRP8BP, PRPF8BP, SPF38, WDR57" ENSG00000060688 "Small nuclear ribonucleoprotein U5 subunit 40" Q96DI7 1 31259568-31296788 "Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026527, HPA027345" Supported Supported "Nuclear speckles" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear speckles" "HPA026527: AB_1858814, HPA027345: AB_2239703" "unprognostic (2.31e-3)" "unprognostic (5.63e-2)" "unprognostic (5.24e-3)" "unprognostic (1.36e-1)" "unprognostic (1.14e-3)" "unprognostic (1.28e-2)" "prognostic unfavorable (4.73e-6)" "unprognostic (2.14e-2)" "unprognostic (2.43e-2)" "unprognostic (2.50e-1)" "unprognostic (1.22e-1)" "unprognostic (8.57e-2)" "unprognostic (2.34e-2)" "unprognostic (1.78e-2)" "unprognostic (5.93e-2)" "unprognostic (4.31e-2)" "unprognostic (6.24e-2)" 17.9 18.9 10.7 21.2 14.6 30.0 20.7 15.5 12.6 17.7 10.3 20.6 16.4 20.1 21.7 19.1 22.5 13.1 14.2 10.4 12.5 17.6 19.3 15.8 35.4 14.5 13.3 20.8 13.0 18.0 15.9 22.3 15.4 20.1 22.1 19.1 15.0 20.8 20.9 18.5 17.6 21.7 13.7 21.3 16.6 21.2 12.8 40.3 18.0 18.1 40.2 24.0 16.7 20.1 71.6 53.6 95.5 78.6 46.7 38.4 66.2 58.8 57.4 104.7 101.9 76.7 69.8 91.8 56.4 46.1 53.9 66.4 145.7 69.8 105.9 99.2 109.3 135.2 72.1 83.9 58.4 150.0 59.3 36.2 54.7 102.1 75.6 34.4 86.1 80.2 129.0 52.9 60.5 51.6 111.3 87.9 171.6 71.1 76.5 87.3 134.5 71.1 44.2 57.7 65.1 63.6 92.3 47.4 116.2 88.0 47.2 94.9 59.5 57.9 85.2 81.5 112.9 43.5 57.1 126.1 47.1 139.3 96.4 102.8 75.8 82.3 98.6 97.3 113.1 93.8 95.1 98.2 93.0 82.6 101.1 115.1 16.4 110.5 92.0 78.4 110.2 161.1 10.7 14.6 15.5 12.6 10.4 12.5 14.5 13.3 15.4 13.7 12.8 20.1 44.1 3.2 6.1 14.7 51.5 53.0 50.2 90.8 41.5 15.6 24.4 30.6 16.5 21.5 32.5 16.5 18.8 108.7 35.7 11.9 43.0 42.5 7.1 21.0 27.5 39.4 34.8 80.8 23.7 35.9 91.3 38.1 28.5 13.9 34.3 36.2 28.9 22.3 56.2 10.1 24.3 18.6 69.2 20.7 48.6 5.4 26.8 31.5 42.7 15.0 44.7 23.8 44.3 23.6 49.0 36.4 20.2 34.3 40.6 55.0 17.0 45.0 27.6 22.2 32.9 31.0 35.1 105.5 89.7 39.6 54.8 61.3 52.4 45.9 36.9 40.6 SNRPA1 "Lea1, U2A'" ENSG00000131876 "Small nuclear ribonucleoprotein polypeptide A'" P09661 15 101281510-101295282 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045622, HPA048499" Supported Supported "Nucleoplasm,Nuclear speckles,Nuclear bodies" NA NA 48000 "Cluster 39: Non-specific - mRNA processing" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Nuclear speckles, Nuclear bodies" "HPA045622: AB_2679394, HPA048499: AB_2680421" "unprognostic (2.73e-1)" "unprognostic (1.48e-1)" "unprognostic (8.09e-2)" "unprognostic (2.20e-1)" "unprognostic (8.08e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (8.56e-5)" "unprognostic (5.80e-2)" "unprognostic (1.66e-3)" "prognostic favorable (8.83e-5)" "unprognostic (4.74e-2)" "unprognostic (6.77e-3)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.06e-2)" "unprognostic (2.84e-1)" "unprognostic (2.43e-1)" "unprognostic (1.37e-2)" 19.0 18.2 11.0 35.5 11.4 68.1 20.8 13.2 15.4 14.7 14.7 30.6 24.3 15.5 33.0 33.8 18.6 12.7 25.8 12.0 11.6 25.2 25.5 19.5 43.3 11.5 11.3 13.6 22.2 18.3 13.9 30.4 11.7 16.3 30.8 15.5 23.1 12.6 19.7 18.5 30.1 19.3 10.9 25.2 23.2 37.8 12.4 37.4 18.3 12.4 51.9 26.3 18.2 12.6 175.5 119.5 112.7 57.4 31.3 25.6 111.3 158.2 72.8 139.2 105.1 255.8 150.7 192.9 89.2 107.8 109.0 101.7 170.2 113.1 148.1 98.0 262.5 151.4 196.7 137.3 24.0 175.1 103.7 21.0 83.0 89.0 111.3 30.9 90.9 147.1 216.1 175.8 86.5 194.6 177.6 185.7 144.5 232.0 100.1 174.5 121.7 194.8 103.3 450.2 88.6 92.7 97.2 109.0 125.1 117.1 105.2 136.4 66.2 74.1 141.0 86.8 160.3 143.5 464.8 378.9 59.9 162.9 89.3 3.8 36.6 21.5 55.7 47.2 55.3 53.0 57.7 56.1 58.0 47.4 46.6 59.0 6.8 48.5 44.0 54.7 68.9 39.0 11.0 11.4 13.2 15.4 12.0 11.6 11.5 11.3 11.7 10.9 12.4 12.6 41.5 19.2 54.6 16.3 71.6 65.6 73.4 141.6 70.6 37.8 41.8 52.6 30.5 18.6 80.3 36.8 12.5 124.3 69.6 37.4 68.4 94.6 96.2 52.7 42.5 47.2 27.0 61.4 30.9 109.0 154.1 51.5 27.0 55.6 65.8 37.7 21.4 35.5 67.0 37.0 29.2 44.2 126.1 24.1 39.2 22.4 34.8 36.4 42.7 13.1 76.4 39.6 47.4 16.6 28.6 95.3 41.8 28.6 76.1 142.3 78.7 87.1 89.2 34.9 13.1 37.9 67.1 192.9 65.9 68.3 50.6 112.3 68.1 42.3 52.4 101.6 SNRPB2 "Msl1, U2B''" ENSG00000125870 "Small nuclear ribonucleoprotein polypeptide B2" P08579 20 16729961-16742564 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 524.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 381.4;SK-MEL-30: 378.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050814, HPA076104" Supported Supported "Nuclear speckles,Cytoplasmic bodies" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles" "Cytoplasmic bodies" "HPA050814: AB_2681245, HPA076104: AB_2732301" "unprognostic (4.73e-2)" "unprognostic (1.78e-1)" "unprognostic (4.02e-1)" "prognostic unfavorable (7.57e-4)" "unprognostic (8.45e-2)" "unprognostic (8.36e-2)" "prognostic unfavorable (6.03e-7)" "unprognostic (4.23e-2)" "unprognostic (5.94e-2)" "unprognostic (1.65e-2)" "unprognostic (2.73e-2)" "unprognostic (4.06e-1)" "prognostic unfavorable (2.79e-4)" "unprognostic (1.21e-1)" "unprognostic (1.78e-1)" "unprognostic (1.14e-2)" "unprognostic (1.77e-1)" 27.5 27.6 23.9 30.9 24.9 53.9 31.0 24.3 35.7 22.3 26.0 26.4 24.3 29.0 35.2 20.8 24.4 21.9 25.0 24.9 25.9 42.3 30.1 22.2 43.3 24.9 25.2 29.1 18.3 26.9 22.6 28.7 24.7 21.9 26.5 11.2 21.1 21.6 30.2 17.0 24.6 27.1 25.6 28.4 23.4 22.6 24.7 37.3 25.6 27.2 36.6 28.9 19.8 27.3 76.0 73.3 94.3 59.1 46.1 57.8 104.7 73.4 60.9 78.0 76.1 84.6 83.5 121.0 56.0 63.0 119.2 69.3 74.9 85.5 111.0 40.0 62.8 111.8 22.4 157.4 53.9 132.0 73.8 57.6 56.0 71.5 55.6 58.1 74.4 81.3 93.8 53.6 80.6 79.2 152.5 159.6 84.2 381.4 97.0 86.1 113.1 84.9 76.9 50.8 49.8 142.3 54.5 147.6 378.7 69.4 93.8 106.5 63.7 71.0 71.2 64.4 122.7 46.9 102.8 134.7 33.7 77.8 157.1 51.8 29.4 47.4 27.3 38.6 35.8 31.5 34.7 31.5 31.6 29.1 30.0 33.4 12.8 31.7 40.5 45.9 48.0 29.9 23.9 24.9 24.3 35.7 24.9 25.9 24.9 25.2 24.7 25.6 24.7 27.3 125.9 44.8 58.0 6.2 128.6 89.1 186.9 238.2 60.3 30.7 93.8 118.5 67.4 107.2 126.5 93.8 0.0 281.4 150.1 79.6 215.2 165.9 163.3 105.3 150.3 124.6 93.3 131.7 12.9 169.2 288.3 120.8 50.0 120.5 132.5 103.2 140.3 139.3 227.3 48.8 14.3 133.3 152.5 157.9 124.6 35.1 172.7 120.5 110.3 8.4 195.4 77.7 153.5 15.1 21.5 169.4 102.7 155.7 91.2 143.8 94.9 524.6 107.2 25.1 98.6 118.7 147.5 192.4 130.4 60.8 96.0 376.9 150.1 94.7 127.7 170.2 SNURF ENSG00000273173 "SNRPN upstream reading frame" Q9Y675 15 24954986-24977850 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 62.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NTERA-2: 191.3;U-698: 112.1" HPA065733 Supported "Nuclear speckles" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 59: Non-specific - Transcription" "Nuclear speckles" "HPA065733: AB_2685548" "unprognostic (2.08e-1)" "unprognostic (2.88e-2)" "unprognostic (6.82e-2)" "unprognostic (4.59e-3)" "unprognostic (4.03e-2)" "unprognostic (1.40e-3)" "unprognostic (4.39e-2)" "unprognostic (6.89e-3)" "unprognostic (1.56e-2)" "unprognostic (6.74e-2)" "unprognostic (8.91e-4)" "unprognostic (3.77e-1)" "unprognostic (1.77e-2)" "unprognostic (6.04e-2)" "unprognostic (1.06e-1)" "unprognostic (1.45e-1)" "unprognostic (1.12e-2)" 8.1 16.1 3.7 6.9 7.5 12.5 5.3 16.3 16.0 12.1 1.2 14.6 1.9 9.6 54.8 5.3 8.5 13.2 50.7 5.6 11.8 14.6 12.9 9.8 10.2 1.5 2.8 13.7 13.5 19.8 28.5 2.7 2.4 15.2 2.5 25.3 8.4 8.3 62.9 3.7 6.4 3.8 0.5 17.2 11.5 3.3 6.5 8.1 15.5 7.4 7.0 12.8 7.3 8.6 0.1 11.9 61.9 44.1 3.1 4.1 0.1 40.7 3.3 4.2 2.8 7.0 36.4 0.5 21.0 2.7 6.0 15.3 0.0 9.1 3.2 14.1 0.0 74.3 50.2 1.8 11.0 79.2 25.4 10.0 2.3 7.7 0.5 22.1 5.2 22.4 7.3 0.2 8.3 0.0 55.5 0.5 191.3 0.0 1.9 54.7 84.7 0.9 3.3 82.0 37.1 29.1 0.0 3.8 22.3 75.2 38.7 7.1 75.8 27.2 30.2 1.0 8.9 58.8 81.6 112.1 43.9 33.6 24.5 17.7 1.5 6.3 14.9 0.7 31.0 22.3 32.9 28.4 2.7 27.8 41.2 38.1 1.7 22.4 3.1 23.6 35.7 20.1 3.7 7.5 16.3 16.0 5.6 11.8 1.5 2.8 2.4 0.5 6.5 8.6 1.0 3.2 3.7 0.0 2.9 0.5 0.6 1.4 2.2 1.6 1.4 1.1 4.1 0.0 1.1 0.0 0.0 0.0 1.1 0.7 3.9 2.1 0.4 0.7 1.2 0.9 0.0 0.8 0.0 2.4 0.0 1.4 1.5 0.7 1.3 2.0 1.1 0.7 0.3 3.3 0.0 2.7 0.0 0.8 0.4 0.3 0.6 0.6 0.0 0.0 0.7 0.4 0.0 0.0 0.0 2.2 2.8 0.4 2.7 0.6 1.1 0.7 4.1 1.5 0.0 0.9 2.0 0.3 0.8 0.7 0.3 0.0 2.8 1.9 1.2 0.3 SRSF11 "NET2, p54, SFRS11" ENSG00000116754 "Serine and arginine rich splicing factor 11" Q05519 1 70205682-70253052 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008762 Supported Supported "Nuclear speckles" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 50: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "HPA008762: AB_1856782" "unprognostic (7.82e-3)" "unprognostic (1.69e-1)" "unprognostic (2.28e-2)" "unprognostic (2.85e-1)" "unprognostic (5.32e-3)" "unprognostic (1.30e-3)" "prognostic unfavorable (3.91e-4)" "unprognostic (2.23e-3)" "unprognostic (5.65e-3)" "unprognostic (3.18e-2)" "unprognostic (1.22e-1)" "unprognostic (6.25e-3)" "prognostic unfavorable (6.53e-6)" "unprognostic (7.79e-2)" "unprognostic (1.63e-1)" "unprognostic (1.90e-1)" "unprognostic (1.43e-2)" 76.4 67.0 39.4 51.4 42.6 136.8 76.9 48.1 64.6 86.6 40.0 73.7 44.7 75.9 70.0 62.1 83.7 45.1 51.9 39.4 46.5 68.8 94.1 70.1 75.8 42.0 40.7 96.3 85.7 43.0 79.8 56.1 43.7 73.7 45.0 57.7 69.5 40.8 66.3 75.9 84.9 39.3 39.7 89.8 72.9 58.4 41.4 75.4 86.2 32.9 64.7 68.5 75.0 47.9 92.8 46.2 118.4 76.2 59.5 79.7 162.4 111.6 57.5 89.0 80.3 81.6 68.0 156.6 74.7 56.5 58.4 77.4 151.5 61.4 120.7 105.9 118.1 159.0 112.4 98.5 71.1 221.0 63.3 64.2 76.0 82.5 83.5 111.3 80.4 79.0 159.1 96.1 88.7 36.4 133.3 163.1 190.9 72.3 76.9 156.1 130.9 99.9 104.3 65.7 99.3 82.1 94.5 101.1 139.8 109.1 80.9 98.1 96.0 97.8 70.4 71.3 102.3 110.4 94.5 169.9 70.2 161.3 87.7 111.7 63.5 103.6 65.7 51.6 74.9 76.3 67.0 65.2 66.1 70.7 72.2 67.8 31.7 85.8 64.6 91.7 80.4 52.7 39.4 42.6 48.1 64.6 39.4 46.5 42.0 40.7 43.7 39.7 41.4 47.9 198.6 211.5 224.9 90.4 208.6 354.0 295.5 229.6 222.5 164.8 166.9 171.7 119.6 115.8 184.5 195.0 118.9 242.0 243.4 123.8 115.4 151.0 64.4 160.0 267.9 186.8 173.8 218.5 219.0 135.3 253.1 228.9 165.6 231.0 194.1 218.1 146.3 152.6 150.4 159.9 183.0 158.3 150.5 124.9 244.4 56.9 255.7 155.4 168.9 126.5 183.1 115.5 145.2 168.9 219.8 144.9 104.7 264.4 234.9 317.8 122.1 101.4 157.8 158.1 170.9 199.1 218.3 270.0 138.0 181.4 353.6 303.7 226.2 195.5 172.9 315.0 SRSF4 "SFRS4, SRP75" ENSG00000116350 "Serine and arginine rich splicing factor 4" Q08170 1 29147743-29181900 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050975 Supported Supported "Nuclear speckles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 36: HEL - Hemostasis" "Cluster 22: Epithelial cell types - Mixed function" "Nuclear speckles" "HPA050975: AB_2681296" "unprognostic (3.26e-3)" "unprognostic (8.08e-2)" "unprognostic (1.29e-2)" "unprognostic (1.57e-3)" "unprognostic (1.37e-1)" "unprognostic (5.89e-2)" "unprognostic (1.89e-3)" "unprognostic (1.63e-1)" "prognostic unfavorable (3.27e-4)" "unprognostic (2.36e-1)" "unprognostic (1.75e-1)" "prognostic unfavorable (4.26e-4)" "prognostic unfavorable (4.30e-4)" "unprognostic (6.25e-3)" "unprognostic (2.80e-1)" "unprognostic (7.75e-3)" "unprognostic (1.60e-2)" 84.7 61.1 43.4 46.8 45.4 77.5 78.2 47.6 46.6 82.3 44.1 86.7 49.6 79.7 38.6 73.5 71.7 36.4 61.9 43.0 46.9 62.9 95.8 83.5 57.4 44.8 43.7 88.2 61.6 38.7 56.0 57.6 45.6 72.0 35.6 51.8 62.5 39.6 94.1 76.2 73.1 40.6 43.0 81.9 66.7 44.5 45.0 63.2 73.7 51.7 43.4 77.7 76.6 46.1 108.2 63.5 117.0 42.8 83.9 63.0 72.5 87.6 65.5 103.3 88.0 58.6 64.9 122.2 79.9 74.5 66.9 99.0 99.7 81.4 104.5 148.6 118.9 185.7 95.6 92.9 87.2 127.8 114.0 51.1 101.1 87.7 111.8 83.9 86.6 70.2 154.8 95.7 71.1 54.1 162.2 110.4 125.2 64.4 60.0 150.6 126.9 83.3 71.1 110.0 71.3 81.4 107.4 61.5 105.8 103.4 41.0 76.3 84.2 82.9 66.1 91.0 146.4 88.0 70.6 134.5 79.4 161.0 91.9 72.7 45.7 102.2 64.6 55.1 63.3 49.0 59.7 70.5 55.8 53.1 51.0 55.0 89.6 48.4 62.3 43.2 78.9 51.1 43.4 45.4 47.6 46.6 43.0 46.9 44.8 43.7 45.6 43.0 45.0 46.1 142.3 80.1 129.8 23.8 94.2 99.8 179.6 65.0 91.0 70.2 50.2 42.9 51.1 45.8 92.8 51.5 85.5 132.7 100.0 68.4 54.8 64.9 8.2 85.4 98.4 131.0 39.0 114.3 20.1 47.2 124.6 87.8 76.5 99.4 91.7 76.2 101.0 75.9 68.8 57.2 21.1 72.7 59.0 69.8 79.0 11.6 85.7 83.4 55.2 14.0 88.6 74.8 92.7 19.6 19.6 56.3 78.8 89.1 121.4 172.3 83.1 58.3 91.7 108.3 72.3 99.5 97.4 64.7 51.9 95.9 103.3 142.8 105.1 75.9 78.7 210.4 SRSF6 "B52, SFRS6, SRP55" ENSG00000124193 "Serine and arginine rich splicing factor 6" Q13247 20 43457893-43466046 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029005, CAB034889" Supported Supported "Nuclear speckles" NA NA 50000 "Cluster 39: Non-specific - mRNA processing" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nuclear speckles" "CAB034889: AB_785899, HPA029005: AB_10610424" "unprognostic (1.51e-1)" "unprognostic (1.26e-1)" "unprognostic (1.98e-1)" "unprognostic (3.25e-2)" "unprognostic (6.41e-2)" "unprognostic (3.91e-2)" "prognostic unfavorable (3.86e-4)" "unprognostic (3.99e-3)" "unprognostic (4.39e-2)" "unprognostic (2.07e-1)" "unprognostic (1.27e-3)" "unprognostic (6.03e-3)" "prognostic unfavorable (2.82e-4)" "unprognostic (1.73e-1)" "unprognostic (2.70e-1)" "unprognostic (4.31e-1)" "unprognostic (1.18e-2)" 43.3 53.7 34.0 34.5 37.5 115.9 56.2 41.4 43.8 44.2 52.7 37.8 36.3 52.7 59.7 32.8 47.4 31.4 31.4 33.3 39.6 47.4 50.3 40.3 48.4 34.5 34.7 58.5 66.3 41.8 48.0 39.3 35.6 48.7 43.4 38.7 45.3 30.0 30.5 48.7 45.4 39.7 35.6 55.9 47.4 30.3 35.7 53.7 50.8 18.1 40.8 29.7 30.4 47.3 52.7 79.1 88.7 57.3 50.7 67.7 86.3 79.6 38.3 55.4 47.1 112.9 55.9 95.9 73.9 73.3 45.1 77.6 91.7 116.9 71.7 40.2 85.7 74.6 83.3 94.1 62.3 94.9 78.9 115.7 61.9 51.0 46.2 85.1 52.7 83.8 63.3 54.5 52.6 112.3 144.5 107.6 57.8 87.4 107.4 100.2 54.4 76.9 63.1 93.7 69.0 90.9 89.5 108.7 105.0 61.7 70.4 103.3 54.9 57.9 61.6 49.9 67.3 98.2 67.3 131.4 69.9 67.2 42.8 26.0 19.9 9.7 19.7 33.4 22.4 16.0 20.8 19.1 24.5 15.9 27.3 25.7 10.8 21.2 29.6 20.4 18.7 22.9 34.0 37.5 41.4 43.8 33.3 39.6 34.5 34.7 35.6 35.6 35.7 47.3 78.9 64.1 80.0 49.6 75.8 94.4 61.0 58.5 50.7 48.9 110.7 78.7 28.7 75.8 61.3 46.0 39.6 97.8 103.3 67.8 88.0 60.2 12.3 60.1 87.7 62.3 101.4 71.1 32.1 43.7 108.2 80.0 70.8 79.1 97.0 103.2 60.7 94.7 56.5 32.0 37.2 97.2 46.8 73.2 93.7 14.7 55.0 77.3 101.4 26.2 61.2 45.0 37.0 89.0 79.6 46.2 74.3 44.8 49.3 68.9 66.7 67.7 47.6 46.4 59.2 166.1 99.8 53.8 61.0 51.5 98.3 139.1 76.4 90.7 105.5 55.3 STK17A DRAK1 ENSG00000164543 "Serine/threonine kinase 17a" Q9UEE5 7 43582758-43650713 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 644.6;T-cells: 273.7;Urothelial cells: 326.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018138, HPA037979" Uncertain Supported "Nuclear speckles,Plasma membrane" Yes No "Cluster 48: NK-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 22: Epithelial cell types - Mixed function" "Nuclear speckles" "Plasma membrane" "HPA018138: AB_2669784, HPA037979: AB_10795247" "unprognostic (1.81e-3)" "unprognostic (1.08e-2)" "unprognostic (2.67e-1)" "unprognostic (5.41e-2)" "unprognostic (5.11e-2)" "unprognostic (3.35e-2)" "unprognostic (1.03e-2)" "unprognostic (9.15e-3)" "unprognostic (2.07e-1)" "unprognostic (6.34e-2)" "unprognostic (1.36e-2)" "unprognostic (6.61e-2)" "unprognostic (2.99e-3)" "unprognostic (3.76e-2)" "unprognostic (3.08e-1)" "unprognostic (1.97e-3)" "unprognostic (3.66e-1)" 6.7 8.1 3.9 7.9 4.2 4.8 5.2 6.9 4.9 4.0 4.0 6.4 3.2 3.5 1.2 7.2 3.9 5.3 10.8 4.0 4.1 6.3 4.6 9.4 14.4 3.4 4.4 6.2 9.1 0.8 4.2 3.2 3.6 4.3 2.4 5.5 5.8 2.1 9.9 4.6 11.5 3.3 3.6 12.6 9.5 9.0 4.3 9.0 3.8 2.5 13.5 5.6 5.0 3.1 5.8 8.2 9.0 5.3 7.8 8.3 1.9 12.3 15.1 6.6 5.9 7.5 3.1 7.9 20.2 15.3 17.8 8.5 3.6 17.4 10.4 16.9 7.0 9.3 8.2 8.4 4.9 21.1 5.6 6.4 26.4 8.2 8.6 36.4 12.6 11.0 16.7 15.1 9.6 3.6 18.2 8.0 17.3 4.1 18.3 8.4 6.9 14.2 15.6 6.7 6.9 11.2 8.1 8.5 6.1 13.6 6.5 10.8 16.9 20.7 8.3 14.3 17.2 13.3 11.2 13.5 18.4 14.0 31.7 0.5 0.0 2.7 2.0 0.0 1.5 2.4 2.0 3.2 0.1 2.2 3.0 3.0 1.6 4.9 0.1 0.4 1.3 0.9 3.9 4.2 6.9 4.9 4.0 4.1 3.4 4.4 3.6 3.6 4.3 3.1 44.2 121.8 33.1 29.0 237.8 181.9 644.6 64.5 99.6 2.9 17.7 37.8 28.7 7.2 69.8 20.2 10.4 54.8 222.3 54.4 33.2 153.0 47.0 129.1 17.4 35.2 7.2 54.1 9.5 95.4 23.3 39.1 78.0 88.3 38.8 17.7 17.9 9.6 16.9 0.0 5.6 34.3 38.7 20.3 65.9 14.7 5.9 60.9 35.6 34.7 42.1 7.9 221.4 39.2 3.7 89.4 73.0 2.6 81.2 192.6 23.8 13.2 42.4 26.3 6.6 39.4 51.3 75.8 36.1 42.3 136.1 66.8 273.7 27.0 18.0 326.1 STK19 "D6S60, G11, RP1" ENSG00000204344 "Serine/threonine kinase 19" P49842 6 31971091-31982821 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in all" 4 "Proximal tubular cells: 348.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HDLM-2: 1.4;HEL: 1.5;HL-60: 1.6;REH: 1.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031511, HPA068559" Uncertain Supported "Nuclear speckles" NA NA "Cluster 30: Non-specific - Translation" "Cluster 72: Non-specific - Transcription" "Cluster 36: HEL - Hemostasis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles" "HPA031511: AB_2673915, HPA068559: AB_2686004" "unprognostic (1.65e-1)" "unprognostic (2.30e-1)" "unprognostic (3.31e-1)" "unprognostic (1.86e-1)" "unprognostic (2.63e-1)" "unprognostic (1.67e-1)" "unprognostic (1.15e-2)" "unprognostic (4.26e-2)" "prognostic unfavorable (1.18e-4)" "unprognostic (3.95e-2)" "unprognostic (2.76e-3)" "unprognostic (2.25e-2)" "unprognostic (1.08e-2)" "unprognostic (1.02e-1)" "unprognostic (1.60e-1)" "unprognostic (2.40e-1)" "unprognostic (4.10e-1)" 1.5 3.6 0.1 0.2 0.1 0.0 1.3 0.4 0.9 2.1 0.0 2.5 0.0 1.4 0.3 1.9 1.0 0.1 1.2 0.0 0.0 1.5 2.2 1.3 0.0 0.0 0.0 1.1 1.1 0.2 1.4 0.4 0.1 2.1 0.0 0.2 0.9 0.1 1.3 2.5 0.7 0.0 0.0 1.2 1.3 1.5 0.1 0.1 1.2 0.0 0.1 2.0 1.5 0.4 0.0 0.1 0.0 0.4 1.1 0.7 0.0 0.3 0.1 0.2 0.4 0.0 0.7 0.6 0.3 0.5 0.0 0.6 0.0 0.2 0.3 1.4 0.4 1.5 0.3 0.0 0.5 1.6 0.0 0.6 0.0 0.3 0.1 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 1.1 0.4 0.0 0.0 0.1 0.3 0.1 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.9 0.0 0.7 0.2 0.0 0.0 1.1 0.0 0.1 0.3 0.2 0.6 0.2 0.0 0.8 0.2 0.3 0.1 0.1 0.3 0.4 0.4 0.0 0.1 0.1 0.1 0.4 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 21.2 9.6 21.5 13.7 16.4 13.0 14.0 23.0 13.6 11.8 26.6 27.6 8.1 18.6 24.6 22.0 20.9 37.2 22.4 13.8 39.2 26.3 85.8 27.8 31.8 20.6 19.3 4.6 8.7 28.3 20.0 23.3 19.4 20.7 9.5 20.1 14.3 21.1 19.3 10.1 8.0 17.3 18.3 8.8 10.0 76.0 20.2 18.3 17.8 11.2 12.5 30.2 13.4 4.5 6.5 23.6 16.4 18.4 11.9 13.2 15.0 348.9 41.8 21.9 32.9 19.6 21.1 39.5 21.0 17.9 18.2 49.7 19.8 45.1 13.1 11.8 SYF2 "CBPIN, DKFZp564O2082, fSAP29, NTC31, p29" ENSG00000117614 "SYF2 pre-mRNA splicing factor" O95926 1 25222276-25232502 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018265, HPA070710" Approved Supported "Nuclear speckles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear speckles" "HPA018265: AB_10962002, HPA070710: AB_2686301" "unprognostic (4.19e-3)" "unprognostic (1.58e-2)" "unprognostic (9.98e-2)" "unprognostic (9.29e-2)" "unprognostic (1.21e-1)" "unprognostic (6.76e-2)" "unprognostic (6.76e-3)" "unprognostic (7.40e-3)" "unprognostic (2.36e-2)" "unprognostic (3.26e-1)" "unprognostic (1.33e-2)" "unprognostic (7.58e-2)" "unprognostic (4.89e-2)" "unprognostic (2.27e-2)" "unprognostic (4.80e-2)" "unprognostic (1.45e-3)" "prognostic favorable (5.72e-4)" 75.3 56.5 37.8 42.6 38.4 147.6 66.9 39.9 48.4 70.1 39.0 71.6 55.4 59.9 72.2 49.3 63.7 40.7 50.0 36.9 41.6 64.0 48.3 46.4 63.8 39.3 38.4 104.5 59.1 67.8 35.3 57.1 40.3 50.3 59.4 29.5 52.0 51.3 89.1 58.5 57.7 47.0 39.2 55.9 61.9 26.9 38.4 77.6 59.0 57.8 76.8 63.2 60.1 41.4 54.0 22.0 54.9 45.4 85.2 109.0 42.4 56.1 91.0 52.7 47.8 13.7 73.0 46.2 75.6 68.1 39.8 47.3 47.6 43.2 76.4 76.2 39.4 52.8 56.1 41.8 86.6 75.9 54.3 79.4 118.2 54.3 75.2 100.4 76.0 61.8 42.0 74.4 75.2 19.8 77.6 104.0 71.7 78.9 32.4 51.3 46.3 78.9 86.9 28.6 47.8 69.5 49.1 44.5 160.5 47.7 38.3 91.5 61.8 45.9 40.6 87.0 46.8 86.7 83.4 48.6 67.6 77.7 45.2 185.5 82.1 222.9 79.1 98.4 95.7 140.0 102.4 99.9 70.0 125.5 108.4 102.0 337.6 111.3 121.6 67.3 129.2 92.7 37.8 38.4 39.9 48.4 36.9 41.6 39.3 38.4 40.3 39.2 38.4 41.4 160.7 128.2 112.8 6.8 176.0 159.3 123.0 238.5 111.5 74.3 134.9 174.1 108.1 147.3 151.3 189.4 83.4 195.7 203.9 211.7 246.5 158.6 78.7 153.2 125.9 137.4 111.4 117.6 10.6 174.2 130.1 121.1 59.1 166.8 232.4 120.9 154.9 131.3 126.4 58.9 10.2 166.0 181.0 231.5 155.4 32.1 214.6 155.4 108.5 3.7 251.8 95.0 217.3 6.0 12.5 154.5 221.1 164.7 83.0 109.5 322.0 273.4 151.0 90.5 164.3 139.5 142.5 98.2 108.8 88.1 171.3 280.6 176.8 95.9 171.8 147.2 TAF5L PAF65B ENSG00000135801 "TATA-box binding protein associated factor 5 like" O75529 1 229593121-229626047 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067941 Supported "Nuclear speckles,Cytoplasmic bodies" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nuclear speckles" "Cytoplasmic bodies" "HPA067941: AB_2685929" "unprognostic (3.41e-1)" "unprognostic (1.34e-1)" "unprognostic (3.39e-2)" "unprognostic (1.93e-1)" "unprognostic (7.46e-2)" "unprognostic (1.94e-1)" "unprognostic (2.91e-1)" "unprognostic (2.36e-1)" "unprognostic (1.63e-1)" "unprognostic (6.84e-2)" "unprognostic (5.17e-3)" "unprognostic (8.16e-3)" "unprognostic (1.91e-3)" "unprognostic (3.21e-1)" "unprognostic (2.99e-1)" "unprognostic (4.99e-2)" "unprognostic (3.11e-1)" 16.3 6.3 7.7 10.5 8.5 22.7 10.5 8.6 8.1 9.2 4.6 12.3 10.6 9.1 5.9 10.6 9.5 11.7 8.4 7.3 7.9 6.6 15.3 11.2 14.0 8.3 8.1 9.3 8.4 9.2 3.8 14.0 8.3 9.2 12.5 10.1 8.2 8.7 14.1 7.2 9.9 11.4 7.5 11.4 9.5 5.5 8.5 14.2 10.5 12.6 10.8 14.0 5.1 9.6 30.2 17.1 23.6 19.8 16.1 16.6 62.4 20.1 23.5 24.3 22.4 23.3 23.9 33.7 20.8 21.4 15.7 24.9 26.4 24.2 22.9 25.5 38.3 26.4 17.7 14.8 17.9 35.3 29.3 18.6 22.9 24.0 20.3 9.4 23.7 34.8 36.1 29.7 22.8 14.6 39.9 18.5 34.1 33.3 13.2 35.0 26.8 34.9 16.6 27.2 23.9 29.4 17.2 22.9 27.9 8.7 27.4 35.6 21.2 20.1 24.7 27.2 42.6 16.1 13.3 37.9 15.4 21.1 32.3 0.0 0.2 0.0 0.4 0.2 0.5 0.2 0.4 0.3 0.3 0.2 0.4 0.4 0.0 0.5 0.3 0.1 0.4 0.2 7.7 8.5 8.6 8.1 7.3 7.9 8.3 8.1 8.3 7.5 8.5 9.6 15.9 3.2 9.4 19.2 8.2 5.7 4.8 2.9 6.2 5.5 8.4 5.3 7.3 5.7 7.1 3.7 12.5 11.0 14.6 12.3 1.9 4.2 3.4 11.0 8.9 8.0 12.0 7.6 11.7 8.3 32.8 7.0 6.1 12.7 0.0 6.1 6.8 13.6 9.6 6.7 15.7 10.2 6.1 6.3 8.4 4.7 4.7 10.9 5.4 13.1 11.8 3.8 4.1 22.1 24.0 6.9 8.3 4.1 10.2 6.6 6.9 3.0 5.1 9.0 13.1 15.4 11.5 6.0 4.6 9.6 5.3 10.4 8.8 5.6 9.9 7.2 TCF12 "bHLHb20, HEB, HsT17266, HTF4, p64" ENSG00000140262 "Transcription factor 12" Q99081 15 56918623-57299281 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 319.8;Microglial cells: 440.3;Oligodendrocyte precursor cells: 618.3;Oligodendrocytes: 1512.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004432, HPA065827" Approved Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Nuclear speckles" "CAB004432: AB_671267, HPA065827: AB_2685564" "unprognostic (1.19e-1)" "unprognostic (1.11e-1)" "unprognostic (8.26e-2)" "unprognostic (1.65e-1)" "unprognostic (2.07e-3)" "unprognostic (1.11e-1)" "unprognostic (6.63e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (8.89e-4)" "unprognostic (7.83e-2)" "unprognostic (7.26e-3)" "unprognostic (5.57e-3)" "prognostic unfavorable (5.24e-5)" "unprognostic (2.03e-1)" "unprognostic (2.93e-1)" "unprognostic (3.15e-2)" "unprognostic (1.41e-1)" 26.1 21.5 29.2 23.4 45.5 21.2 29.5 37.1 34.0 75.6 17.2 26.7 28.4 47.9 24.3 26.6 46.3 37.1 21.8 30.5 32.6 28.4 25.0 28.9 26.0 43.1 39.3 43.3 19.7 44.0 11.5 33.4 38.3 32.0 30.3 29.4 23.3 28.3 20.5 21.3 28.4 44.1 34.5 25.0 25.5 27.4 35.5 133.0 29.0 26.6 28.1 31.2 22.4 55.7 25.4 50.8 204.5 70.6 90.0 79.0 36.1 52.2 89.6 45.1 58.9 34.0 20.3 35.5 42.3 78.3 33.4 30.4 84.3 37.3 56.7 47.5 29.8 71.7 52.7 40.4 62.4 46.1 36.1 69.4 66.2 42.9 112.2 60.1 81.0 163.0 81.7 46.8 61.8 9.5 109.4 25.0 57.5 26.4 20.9 143.2 234.9 33.9 61.5 53.1 43.6 121.2 58.7 21.0 52.0 65.3 33.6 93.9 63.2 75.5 57.5 32.2 78.2 24.6 49.7 59.4 40.8 86.3 90.9 27.4 13.8 11.3 17.4 17.9 14.3 13.4 14.0 16.5 20.0 14.7 16.2 14.8 1.5 16.8 26.3 8.4 23.0 14.1 29.2 45.5 37.1 34.0 30.5 32.6 43.1 39.3 38.3 34.5 35.5 55.7 35.5 54.5 19.6 212.9 37.7 26.6 20.6 14.2 44.9 13.8 24.0 20.4 19.3 14.3 21.2 16.5 35.5 10.4 20.6 17.0 13.7 16.0 23.7 25.9 148.0 38.2 9.0 34.9 117.7 11.8 15.5 42.3 52.0 33.3 23.4 26.9 25.7 18.2 27.5 13.5 319.8 16.8 10.2 38.1 30.0 19.9 25.7 33.0 14.2 440.3 17.4 29.0 18.6 618.3 1512.7 15.9 18.4 34.6 29.1 23.4 20.0 15.3 15.9 23.3 46.0 39.9 36.5 22.2 15.0 33.6 33.8 13.0 28.4 16.5 20.1 18.2 TCF15 "bHLHa40, EC2, PARAXIS" ENSG00000125878 "Transcription factor 15" Q12870 20 603797-610398 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "heart muscle: 27.8;skeletal muscle: 13.2;tongue: 9.1" "Cell type enriched" "Detected in some" 6 "Adipocytes: 260.0" "Cancer enhanced" "Detected in many" "testis cancer: 3.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HEL: 10.6;HMC-1: 16.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA050998, HPA060221" Approved Supported "Nuclear speckles" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles" "HPA050998: AB_2681302, HPA060221: AB_2684225" "unprognostic (2.12e-2)" "unprognostic (1.96e-2)" "unprognostic (1.58e-2)" "unprognostic (3.55e-2)" "unprognostic (1.29e-1)" "unprognostic (4.62e-2)" "unprognostic (5.57e-2)" "unprognostic (2.33e-1)" "unprognostic (2.81e-1)" "prognostic unfavorable (3.25e-4)" "unprognostic (1.52e-1)" "unprognostic (9.43e-2)" "unprognostic (1.27e-3)" "unprognostic (7.21e-2)" "unprognostic (8.56e-2)" "unprognostic (5.11e-1)" "unprognostic (6.99e-2)" 7.0 0.6 1.3 0.1 1.2 0.0 4.6 1.2 1.4 0.2 0.9 1.6 0.1 0.8 0.0 0.3 0.4 0.1 27.8 1.1 1.2 1.5 0.2 0.6 0.1 1.3 1.3 0.2 0.3 0.1 0.4 3.3 1.4 0.3 0.0 0.0 0.6 0.0 13.2 0.2 0.5 0.2 1.3 0.0 0.6 2.0 1.3 0.0 0.5 9.1 0.0 0.9 0.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 1.5 0.0 0.0 0.0 2.9 10.6 0.0 0.0 0.0 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.7 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.1 0.0 0.0 1.7 0.0 0.0 0.0 1.5 0.0 1.3 0.0 3.0 0.0 1.4 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.2 1.2 1.4 1.1 1.2 1.3 1.3 1.4 1.3 1.3 1.2 260.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.6 0.5 0.6 1.0 15.6 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.7 0.2 0.2 41.2 0.0 0.0 0.0 0.0 0.1 2.2 0.0 0.6 0.0 0.1 7.1 0.0 0.1 1.7 0.5 0.0 0.0 0.0 0.4 0.2 0.0 0.5 0.0 2.8 0.0 0.1 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 13.1 3.7 23.3 2.3 0.6 0.0 0.0 0.0 0.2 0.5 0.0 0.0 TCP11L2 MGC40368 ENSG00000166046 "T-complex 11 like 2" Q8N4U5 12 106301929-106347003 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 98.8;choroid plexus: 79.4" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 111.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 67.0" "Lineage enriched" "Detected in all" 5 "granulocytes: 67.0" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 25.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039483, HPA042188" Uncertain Supported "Nuclear speckles" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nuclear speckles" "HPA039483: AB_10795291, HPA042188: AB_10794415" "unprognostic (1.41e-1)" "unprognostic (3.17e-1)" "unprognostic (1.24e-1)" "unprognostic (8.15e-2)" "unprognostic (1.97e-1)" "prognostic favorable (9.52e-4)" "unprognostic (3.87e-3)" "unprognostic (2.43e-1)" "unprognostic (2.11e-1)" "unprognostic (9.05e-3)" "unprognostic (5.44e-2)" "unprognostic (1.33e-1)" "unprognostic (1.22e-2)" "unprognostic (1.24e-1)" "unprognostic (1.28e-1)" "unprognostic (5.02e-2)" "unprognostic (3.67e-1)" 11.5 8.8 16.4 7.9 43.0 30.3 10.3 32.6 24.5 9.2 79.4 7.7 7.5 10.0 4.2 22.9 13.1 9.5 22.6 12.9 22.4 6.7 6.5 16.7 10.2 46.6 33.2 9.0 6.0 10.2 4.8 14.5 43.3 6.7 9.0 10.3 12.1 6.5 17.9 13.9 9.8 8.2 28.4 11.7 12.1 10.6 30.8 13.6 11.6 23.0 16.8 8.5 9.3 98.8 3.3 8.1 1.1 2.3 10.6 12.2 5.0 2.1 10.2 1.3 3.2 1.3 4.3 1.1 3.2 8.1 3.0 15.2 1.0 4.5 2.3 1.7 3.3 0.7 3.4 5.1 10.4 0.3 2.1 15.4 10.2 1.6 7.6 25.1 7.5 5.9 2.0 1.5 1.9 2.4 2.0 1.7 1.4 4.4 5.0 1.0 0.3 3.8 10.1 15.2 5.0 3.6 5.5 1.7 6.0 8.4 4.6 0.3 5.7 1.9 1.6 2.9 0.5 10.0 0.8 3.8 5.3 0.3 1.0 29.6 6.9 11.0 4.8 3.1 3.6 12.4 9.9 5.4 1.7 10.6 12.2 8.3 67.0 4.3 5.3 1.2 12.3 3.8 16.4 43.0 32.6 24.5 12.9 22.4 46.6 33.2 43.3 28.4 30.8 98.8 12.6 12.8 14.4 15.0 23.1 1.1 3.4 4.4 5.7 8.1 3.5 5.5 10.5 0.0 8.6 3.7 22.9 1.5 13.4 4.2 1.9 3.6 6.3 28.6 7.3 12.1 4.2 33.7 7.7 2.6 0.8 10.5 11.2 20.5 2.5 4.3 6.1 1.5 1.2 21.9 23.9 5.0 2.0 3.1 2.0 4.5 5.9 5.2 3.6 12.2 8.0 3.1 10.3 9.0 111.0 3.7 4.8 2.6 9.9 4.0 5.9 1.2 16.7 13.4 13.1 11.8 7.2 4.3 3.0 6.3 2.6 15.1 12.4 8.0 1.2 8.7 TERT "EST2, hEST2, TCS1, TP2, TRT" ENSG00000164362 "Telomerase reverse transcriptase" O14746 5 1253147-1295068 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "DNA-binding, Nucleotidyltransferase, Ribonucleoprotein, RNA-directed DNA polymerase, Transferase" "Cancer-related genes, Disease variant, Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.4;Intestinal goblet cells: 1.0;Plasma cells: 2.8;Spermatocytes: 1.5;Spermatogonia: 4.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 438.0;fHDF/TERT166: 429.4;HBEC3-KT: 929.2;hTEC/SVTERT24-B: 560.1;LHCN-M2: 252.2;TIME: 799.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA054641, HPA065897" Supported Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm "Nuclear speckles, Cytosol" "HPA054641: AB_2682554, HPA065897: AB_2685576" "unprognostic (1.21e-2)" "unprognostic (2.88e-2)" "unprognostic (1.24e-3)" "unprognostic (1.53e-1)" "unprognostic (1.43e-3)" "unprognostic (6.42e-3)" "unprognostic (1.85e-2)" "unprognostic (2.21e-1)" "unprognostic (6.91e-2)" "unprognostic (1.89e-1)" "unprognostic (3.59e-1)" "unprognostic (9.16e-4)" "unprognostic (8.84e-11)" "unprognostic (1.92e-1)" "unprognostic (2.15e-1)" "unprognostic (3.35e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 213.2 438.0 3.2 0.0 173.9 31.7 59.4 0.3 0.1 3.0 0.2 429.4 0.1 0.1 1.0 929.2 29.1 0.0 1.7 0.1 0.0 0.4 0.1 0.5 1.2 0.0 22.9 560.1 6.8 1.3 1.5 1.8 2.9 0.2 252.2 0.4 0.2 9.4 2.9 0.1 1.3 2.1 0.0 5.4 23.9 0.5 0.2 2.1 0.1 0.0 0.2 0.0 0.1 0.3 799.9 0.0 0.0 0.0 0.0 0.9 0.5 0.7 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 4.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 THOC6 "fSAP35, MGC2655, WDR58" ENSG00000131652 "THO complex 6" Q86W42 16 3024027-3027755 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, mRNA processing, mRNA splicing, mRNA transport, Transport" "Developmental protein, RNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 107.8;Extravillous trophoblasts: 121.1;Prostatic glandular cells: 109.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052953 Uncertain Supported "Nucleoplasm,Nuclear speckles" No No "Cluster 28: Myeloid DCs - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Nuclear speckles" "HPA052953: AB_2681997" "unprognostic (2.07e-2)" "unprognostic (4.13e-3)" "unprognostic (1.70e-1)" "unprognostic (2.04e-1)" "unprognostic (2.08e-1)" "unprognostic (2.91e-1)" "unprognostic (7.82e-3)" "unprognostic (1.81e-1)" "unprognostic (1.31e-1)" "unprognostic (2.20e-2)" "unprognostic (5.15e-2)" "unprognostic (3.44e-2)" "prognostic unfavorable (4.40e-4)" "unprognostic (3.59e-1)" "unprognostic (1.43e-1)" "unprognostic (6.17e-2)" "unprognostic (9.43e-2)" 17.0 16.9 8.6 16.1 9.1 23.5 15.3 9.6 11.2 16.1 9.7 17.9 18.8 20.3 6.0 19.3 13.9 10.5 15.8 8.6 9.2 22.2 21.3 17.5 20.8 11.6 9.1 11.6 12.9 10.8 17.4 18.2 11.8 21.1 10.1 2.1 15.2 12.2 25.9 24.9 19.2 12.5 9.2 22.7 15.6 10.4 10.2 19.6 15.7 8.4 16.1 17.1 16.5 9.5 37.3 59.6 42.0 45.0 21.1 23.9 74.4 11.3 25.7 25.7 37.8 39.6 42.8 70.0 36.0 18.9 19.1 49.9 46.3 35.6 14.0 62.3 59.9 38.0 58.6 58.7 35.9 56.2 80.0 24.3 42.6 31.4 76.9 32.4 24.1 39.7 56.1 36.5 12.8 87.0 32.0 103.3 76.2 21.4 25.3 84.7 31.6 82.4 27.1 18.6 86.4 41.0 31.8 49.9 21.7 18.1 35.9 60.0 20.1 26.8 61.1 30.6 41.3 26.3 24.3 85.5 7.0 38.1 27.3 2.4 61.3 13.6 35.2 62.2 36.2 37.8 32.6 34.7 88.6 43.2 37.1 39.1 4.4 38.8 35.7 74.3 38.0 45.4 8.6 9.1 9.6 11.2 8.6 9.2 11.6 9.1 11.8 9.2 10.2 9.5 11.0 19.2 7.4 1.6 24.7 68.2 84.9 59.0 30.7 3.7 22.1 20.8 3.3 14.3 18.9 18.4 2.1 107.8 23.3 23.2 35.2 33.1 5.4 17.9 19.0 17.9 25.8 30.3 1.9 23.5 121.1 24.6 15.3 25.8 12.0 15.6 6.4 10.3 51.8 3.3 1.7 32.3 44.7 19.4 37.3 3.2 14.9 23.4 24.9 2.8 39.6 3.2 15.5 0.5 4.2 21.5 28.0 12.0 19.7 109.4 32.1 32.0 8.7 2.4 6.6 23.4 31.9 5.3 23.3 23.3 44.9 77.2 20.4 20.9 42.2 46.8 THOC7 "FLJ23445, fSAP24, NIF3L1BP1" ENSG00000163634 "THO complex 7" Q6I9Y2 3 63833870-63863868 "Predicted intracellular proteins" "mRNA processing, mRNA splicing, mRNA transport, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 1032.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044143 Approved Supported "Nuclear speckles,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Nuclear speckles, Cytosol" "HPA044143: AB_10794892" "unprognostic (4.33e-2)" "unprognostic (9.68e-2)" "unprognostic (1.75e-2)" "unprognostic (1.30e-1)" "unprognostic (2.26e-2)" "unprognostic (2.86e-1)" "unprognostic (1.20e-3)" "unprognostic (3.53e-2)" "unprognostic (1.85e-2)" "unprognostic (1.52e-2)" "unprognostic (2.86e-2)" "unprognostic (9.90e-2)" "unprognostic (3.26e-2)" "unprognostic (1.51e-2)" "unprognostic (5.18e-2)" "unprognostic (4.25e-2)" "unprognostic (2.31e-1)" 54.7 63.5 57.1 43.2 60.0 80.1 75.1 58.1 85.1 54.4 52.0 69.9 64.2 50.5 53.2 73.1 43.0 48.6 88.0 61.5 59.1 67.8 73.5 40.9 68.1 58.4 59.1 44.4 62.3 52.1 33.5 53.5 57.1 43.8 69.1 64.5 50.5 49.5 103.5 64.2 53.7 59.6 57.3 38.2 49.1 47.6 57.8 72.3 44.4 104.0 68.0 60.8 50.3 61.1 141.2 83.5 95.6 23.9 125.1 172.5 89.6 120.2 126.9 139.2 140.1 101.6 151.5 168.3 49.1 155.1 139.2 79.3 107.5 190.4 194.1 169.6 75.5 150.2 102.8 117.2 130.1 212.6 69.6 123.9 157.2 118.4 213.1 137.6 155.1 110.0 116.8 158.6 170.2 1032.4 186.4 186.9 120.4 304.8 65.5 132.3 89.7 227.4 245.4 128.0 47.3 107.8 105.0 147.6 171.6 93.9 93.6 289.6 113.6 100.8 105.9 125.1 216.3 101.3 162.3 204.1 125.3 268.3 133.5 73.1 40.4 33.1 38.7 47.7 54.0 46.7 47.9 53.2 59.0 31.5 40.5 43.4 23.4 55.6 41.9 54.0 61.7 35.6 57.1 60.0 58.1 85.1 61.5 59.1 58.4 59.1 57.1 57.3 57.8 61.1 82.6 89.8 45.0 14.4 59.2 61.6 91.2 179.9 70.6 53.5 70.9 121.3 143.8 81.5 102.9 84.6 18.8 180.3 66.0 62.1 207.4 145.2 84.7 100.7 75.6 57.8 55.2 159.7 26.8 126.9 166.1 65.4 47.4 73.8 54.4 74.3 44.6 78.1 111.6 48.8 26.4 106.3 101.7 75.6 58.9 89.7 88.9 70.2 67.6 14.0 173.1 82.5 93.7 12.5 18.9 127.6 86.7 71.5 53.3 96.6 108.8 241.2 102.1 73.1 52.6 66.9 83.4 244.9 54.5 116.6 71.6 213.4 68.0 80.7 133.2 95.7 UBE4A "E4, KIAA0126, UBOX2, UFD2" ENSG00000110344 "Ubiquitination factor E4A" Q14139 11 118359600-118399211 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA055035, HPA064010" Approved Supported "Nuclear speckles" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 59: Non-specific - Transcription" "Nuclear speckles" "HPA055035: AB_2682679, HPA064010: AB_2685174" "unprognostic (1.32e-2)" "unprognostic (8.15e-2)" "unprognostic (5.23e-3)" "unprognostic (3.34e-1)" "unprognostic (2.80e-2)" "unprognostic (1.97e-1)" "unprognostic (7.67e-3)" "unprognostic (3.31e-1)" "unprognostic (1.30e-1)" "unprognostic (4.67e-2)" "unprognostic (6.01e-2)" "unprognostic (5.83e-2)" "unprognostic (7.73e-3)" "unprognostic (4.74e-2)" "unprognostic (5.94e-2)" "unprognostic (2.72e-1)" "unprognostic (8.86e-2)" 18.6 14.1 15.9 20.3 17.8 17.7 18.0 25.5 20.5 16.1 15.7 17.4 19.1 18.9 18.6 15.0 15.5 15.6 19.7 15.1 20.2 18.0 27.6 17.0 22.5 18.9 18.1 19.1 19.5 19.0 9.5 17.5 20.2 19.0 20.7 18.4 16.1 14.9 22.1 24.0 20.5 18.1 16.5 19.7 23.9 17.7 19.7 21.3 18.4 15.9 21.6 14.7 12.7 24.4 18.8 17.9 22.4 22.5 38.0 34.9 22.3 27.1 28.1 19.7 24.0 49.7 44.9 39.3 51.0 34.4 26.5 40.3 31.9 25.7 32.6 22.3 14.8 64.5 15.4 25.7 32.6 36.8 47.3 35.4 18.2 40.4 39.3 26.3 33.3 33.9 37.2 35.9 28.7 35.4 31.5 36.5 20.9 37.7 22.7 20.0 32.5 40.2 21.6 43.1 20.3 21.1 39.2 33.5 12.3 24.2 44.8 16.6 34.6 29.0 19.0 25.1 22.8 10.5 13.8 36.4 16.1 41.6 30.4 14.2 9.5 9.7 7.5 10.5 5.8 5.1 5.6 5.4 9.8 3.5 6.0 5.4 9.6 6.5 12.8 5.7 7.0 4.8 15.9 17.8 25.5 20.5 15.1 20.2 18.9 18.1 20.2 16.5 19.7 24.4 28.7 12.8 31.9 45.7 27.5 26.8 22.0 20.4 25.6 19.5 26.3 18.0 18.2 10.0 27.8 14.7 18.8 20.3 30.6 25.5 5.9 19.8 18.0 23.7 35.3 20.9 18.6 26.9 46.2 28.5 19.8 24.2 41.8 31.7 10.8 25.7 19.2 44.6 21.9 16.8 56.3 20.1 30.5 27.9 23.1 15.2 17.1 33.2 24.9 36.5 32.4 20.5 24.7 55.8 80.9 27.0 18.3 21.4 42.0 23.1 29.0 11.5 37.5 16.8 19.7 23.4 23.6 35.3 22.0 30.3 39.2 24.8 31.0 26.0 20.3 26.1 UHMK1 "KIS, Kist" ENSG00000152332 "U2AF homology motif kinase 1" Q8TAS1 1 162497251-162529631 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, RNA-binding, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077624 Supported "Nucleoplasm,Nuclear speckles,Vesicles" NA No "Cluster 51: Monocytes - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Nuclear speckles" Vesicles "HPA077624: " "unprognostic (6.69e-2)" "unprognostic (1.28e-1)" "unprognostic (1.05e-1)" "unprognostic (1.46e-1)" "unprognostic (1.28e-1)" "unprognostic (1.33e-1)" "unprognostic (2.08e-2)" "unprognostic (8.16e-2)" "unprognostic (9.63e-2)" "unprognostic (1.82e-1)" "unprognostic (7.81e-3)" "unprognostic (9.10e-2)" "unprognostic (3.11e-1)" "unprognostic (3.44e-2)" "unprognostic (9.08e-2)" "unprognostic (8.77e-2)" "unprognostic (4.66e-2)" 26.8 23.3 21.2 23.3 24.6 40.3 19.3 18.1 21.2 15.1 16.6 19.2 19.1 11.7 14.1 13.3 14.4 13.7 11.6 26.0 28.3 31.2 38.1 17.5 30.8 24.9 28.5 11.9 11.0 27.8 7.8 17.1 28.3 16.2 19.6 10.5 13.5 18.5 25.8 11.9 23.4 10.8 19.8 25.4 20.0 12.2 26.1 24.6 19.4 25.9 28.9 18.1 10.5 19.4 61.9 28.4 14.6 35.8 40.7 31.9 32.7 79.7 43.2 63.9 45.7 18.6 37.8 50.2 67.8 60.0 31.2 34.9 28.2 44.1 102.4 69.1 20.4 49.8 34.3 16.9 31.3 73.4 55.5 33.0 45.8 63.2 59.9 44.6 37.4 34.2 44.1 67.7 111.4 26.0 39.3 19.4 19.4 46.1 37.8 24.9 64.9 41.9 42.6 62.8 26.4 24.3 70.5 64.6 52.2 19.9 56.0 81.0 58.5 72.7 41.0 50.8 112.6 69.2 103.5 58.0 60.5 35.3 67.3 3.6 2.0 2.4 4.8 5.3 4.9 3.2 3.5 4.0 2.3 3.6 3.5 4.0 1.3 3.7 6.1 2.6 3.1 2.6 21.2 24.6 18.1 21.2 26.0 28.3 24.9 28.5 28.3 19.8 26.1 19.4 37.6 19.2 41.2 20.9 75.6 29.4 33.7 38.5 34.7 24.4 39.4 20.2 35.1 40.0 53.8 53.3 12.5 26.2 81.0 53.9 56.7 27.6 55.6 35.1 35.7 33.4 33.5 51.6 37.0 23.2 38.1 25.5 43.3 44.4 45.7 23.3 31.1 85.1 30.0 23.5 27.4 34.1 48.8 73.5 47.5 58.4 21.5 60.0 28.4 33.7 58.0 14.6 74.2 20.6 29.5 40.4 33.0 19.5 47.2 59.9 60.8 62.2 50.9 23.0 0.0 29.2 27.8 25.1 29.6 45.2 24.6 22.4 69.4 31.4 39.3 58.3 UNC45A "GC-UNC45, SMAP-1" ENSG00000140553 "Unc-45 myosin chaperone A" Q9H3U1 15 90930180-90954093 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Myogenesis" "Chaperone, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039228 Approved Supported "Nuclear speckles,Cytosol" NA NA 17000 "Cluster 27: Non-specific - Gene expression" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "Nuclear speckles" Cytosol "HPA039228: AB_2676402" "unprognostic (1.46e-1)" "unprognostic (3.83e-2)" "unprognostic (4.51e-2)" "unprognostic (1.97e-1)" "unprognostic (2.68e-2)" "unprognostic (1.70e-3)" "prognostic unfavorable (7.72e-4)" "unprognostic (2.27e-2)" "unprognostic (1.58e-1)" "unprognostic (1.16e-1)" "unprognostic (1.98e-1)" "unprognostic (9.85e-2)" "prognostic favorable (7.46e-7)" "unprognostic (9.30e-2)" "unprognostic (1.74e-1)" "unprognostic (1.95e-1)" "unprognostic (2.28e-2)" 25.0 25.3 7.7 16.7 8.2 17.3 23.2 8.6 9.1 32.0 10.0 41.2 16.4 38.1 11.0 31.4 28.4 17.3 15.9 7.8 7.7 18.9 13.0 20.2 18.9 8.9 11.6 26.1 22.3 33.2 17.5 19.6 9.5 25.2 13.4 5.6 25.8 34.1 9.6 37.7 23.5 28.0 8.3 19.7 28.5 13.1 9.6 18.0 19.5 10.6 17.3 39.3 29.4 8.0 38.2 76.3 30.9 27.2 83.0 38.0 27.3 42.4 36.2 56.5 45.1 61.3 49.4 44.7 55.5 53.8 32.5 82.1 52.9 54.4 26.6 49.8 75.9 86.2 77.0 44.4 46.8 21.5 56.2 47.3 65.8 55.7 40.5 54.2 77.5 35.1 38.6 35.8 43.3 62.2 28.1 18.6 41.8 69.5 38.0 54.8 46.9 48.1 38.4 89.2 43.1 39.4 57.1 55.9 54.3 36.8 50.8 44.3 77.0 48.0 34.1 40.4 45.0 33.6 50.5 21.1 46.6 49.7 49.8 11.5 8.3 5.0 11.8 7.3 11.3 7.9 9.6 9.1 10.4 6.3 7.8 7.4 1.6 9.8 11.6 9.1 9.3 9.8 7.7 8.2 8.6 9.1 7.8 7.7 8.9 11.6 9.5 8.3 9.6 8.0 21.7 22.4 22.4 9.4 23.2 16.3 24.8 26.1 30.1 27.2 17.2 19.6 12.7 35.8 23.8 18.4 18.8 53.6 17.5 26.9 13.7 33.6 26.7 12.8 20.3 25.3 37.0 25.2 19.1 18.2 22.7 23.7 26.5 22.1 29.2 30.9 18.9 13.4 28.2 18.5 18.4 15.9 26.4 12.2 14.0 29.0 29.5 20.7 19.6 9.4 28.8 21.5 27.8 7.1 11.0 23.3 26.0 51.6 20.6 16.8 22.0 19.6 11.7 35.1 32.9 15.2 33.9 24.8 6.4 33.9 18.8 46.2 21.4 26.0 22.7 20.3 USP36 "FLJ12851, KIAA1453" ENSG00000055483 "Ubiquitin specific peptidase 36" Q9P275 17 78787381-78841441 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012082, HPA012395, HPA052860" Uncertain Supported Enhanced "Nucleoli,Nucleoli rim,Nuclear speckles" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 50: Non-specific - Ribosome" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 24: Non-specific - Transcription regulation" "Nucleoli, Nucleoli rim" "Nuclear speckles" "HPA012082: AB_1858682, HPA012395: , HPA052860: AB_2681974" "unprognostic (1.94e-2)" "unprognostic (2.80e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (5.18e-5)" "unprognostic (9.35e-2)" "unprognostic (1.98e-1)" "unprognostic (2.50e-3)" "unprognostic (1.35e-1)" "unprognostic (2.04e-1)" "unprognostic (1.33e-1)" "unprognostic (1.68e-2)" "unprognostic (2.78e-2)" "unprognostic (1.31e-2)" "unprognostic (1.45e-1)" "unprognostic (1.81e-1)" "unprognostic (4.03e-3)" "unprognostic (1.78e-1)" 43.9 37.9 20.0 21.5 21.9 46.6 32.9 29.3 23.9 32.6 27.5 31.2 13.4 26.8 22.9 25.0 34.2 18.7 30.2 21.4 20.6 34.4 30.3 36.1 20.6 22.6 21.3 67.4 44.5 18.1 50.3 26.0 21.5 36.2 15.8 26.3 24.9 13.1 30.3 40.4 26.6 16.3 19.4 30.7 31.2 22.2 21.2 15.1 31.6 11.7 20.5 29.3 29.8 30.1 42.7 50.3 14.6 26.9 30.5 33.7 27.8 34.1 34.5 32.1 21.5 49.2 21.0 54.0 16.9 30.6 34.8 30.6 34.5 25.4 57.0 13.0 52.1 49.4 81.0 51.9 31.3 54.7 26.0 29.5 41.0 45.8 101.6 24.7 28.3 24.1 40.0 55.3 26.8 32.6 50.1 55.1 22.6 31.6 39.9 38.1 31.8 36.3 20.2 44.1 42.8 25.8 24.5 112.5 63.7 31.3 29.2 34.4 24.3 75.2 35.3 44.3 61.1 40.7 17.4 66.1 29.6 41.9 24.0 10.1 3.0 2.4 5.5 4.2 6.5 5.1 5.2 4.8 1.8 4.7 5.7 5.6 4.3 4.5 2.7 9.7 3.8 1.9 20.0 21.9 29.3 23.9 21.4 20.6 22.6 21.3 21.5 19.4 21.2 30.1 27.4 12.8 37.4 23.5 55.9 51.7 28.4 8.2 40.9 33.2 18.1 16.9 14.1 18.6 18.8 14.7 33.3 8.3 66.3 14.4 5.9 10.2 20.7 22.3 24.0 28.4 18.5 14.7 19.0 9.6 11.3 26.6 25.0 42.7 20.3 12.8 12.1 16.5 43.3 26.9 22.5 18.6 10.2 24.5 72.8 8.5 11.8 49.4 30.2 10.3 14.9 13.2 16.5 13.6 19.8 13.2 8.4 12.4 57.1 32.4 7.3 5.0 11.1 32.1 6.6 22.1 23.1 18.4 16.5 24.4 43.3 12.9 73.6 13.1 18.6 22.2 WRN "RECQ3, RECQL2" ENSG00000165392 "WRN RecQ like helicase" Q14191 8 31033788-31176138 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Exonuclease, Helicase, Hydrolase, Multifunctional enzyme, Nuclease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 74.7;Early spermatids: 116.3;Oligodendrocytes: 88.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028661 Approved Supported "Nuclear speckles" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Nuclear speckles" "HPA028661: AB_10602255" "unprognostic (8.73e-2)" "unprognostic (9.33e-2)" "unprognostic (1.51e-3)" "unprognostic (3.85e-2)" "unprognostic (1.41e-1)" "unprognostic (1.85e-2)" "unprognostic (2.21e-3)" "unprognostic (1.25e-1)" "unprognostic (1.07e-1)" "unprognostic (1.16e-2)" "unprognostic (1.27e-2)" "unprognostic (6.63e-2)" "unprognostic (1.53e-2)" "unprognostic (6.51e-2)" "unprognostic (2.49e-1)" "unprognostic (1.00e-2)" "unprognostic (2.66e-1)" 3.0 3.6 1.7 3.2 1.7 8.2 4.8 4.1 2.4 3.0 2.6 3.5 1.5 6.4 3.2 2.7 2.9 2.4 1.7 1.6 1.7 2.1 2.5 2.4 2.5 1.8 2.1 5.2 2.6 2.0 2.1 3.6 1.8 3.5 2.9 4.4 3.5 2.6 2.1 4.1 2.5 4.2 1.2 3.1 2.3 3.0 1.9 3.2 3.2 2.2 3.0 2.6 2.3 3.1 4.4 5.9 10.8 5.3 6.7 9.8 5.0 4.7 4.9 6.4 6.6 2.7 1.5 10.0 4.6 4.3 4.4 2.4 6.4 3.8 9.7 3.3 4.3 9.6 4.9 4.4 5.4 8.7 4.3 7.1 3.7 3.6 6.2 3.9 7.7 6.1 14.5 5.0 6.8 2.0 17.5 6.6 7.7 5.1 3.2 7.5 7.5 6.7 2.9 4.4 3.3 5.2 6.9 2.7 3.8 4.9 2.9 5.3 9.1 6.2 3.8 3.1 4.9 1.4 3.0 14.6 5.5 3.8 4.2 0.8 0.2 0.3 0.3 0.1 0.4 0.5 0.5 0.3 0.2 0.5 0.3 0.4 0.3 1.1 0.1 0.1 0.3 0.1 1.7 1.7 4.1 2.4 1.6 1.7 1.8 2.1 1.8 1.2 1.9 3.1 17.5 9.6 10.6 74.7 15.1 13.5 11.7 5.3 18.8 14.5 14.7 10.5 7.5 15.7 8.8 16.5 22.9 7.1 18.0 5.3 1.9 6.7 116.3 15.8 32.3 12.5 2.4 49.2 59.7 9.8 5.7 15.2 21.9 17.1 2.5 18.5 7.1 9.7 5.3 15.2 54.9 13.8 8.2 5.3 6.6 12.8 19.0 7.8 10.6 51.5 6.9 14.3 4.1 61.3 88.6 9.1 4.2 14.3 16.6 15.3 3.9 2.7 10.0 19.8 6.6 20.2 15.3 10.9 19.2 10.1 10.2 5.6 13.0 15.2 7.7 11.0 YLPM1 "C14orf170, PPP1R169, ZAP" ENSG00000119596 "YLP motif containing 1" P49750 14 74763316-74859435 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048070, HPA061123" Uncertain Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nuclear speckles" "HPA048070: AB_2680247, HPA061123: AB_2684435" "unprognostic (2.17e-1)" "unprognostic (3.32e-2)" "unprognostic (3.95e-1)" "unprognostic (2.98e-1)" "unprognostic (3.79e-2)" "unprognostic (7.64e-2)" "unprognostic (3.22e-3)" "unprognostic (8.74e-2)" "unprognostic (3.60e-2)" "unprognostic (2.56e-1)" "unprognostic (7.83e-3)" "unprognostic (6.63e-2)" "prognostic favorable (6.08e-7)" "unprognostic (1.09e-2)" "unprognostic (2.41e-1)" "unprognostic (1.87e-1)" "unprognostic (1.60e-1)" 13.3 13.0 12.5 10.4 12.8 17.6 13.8 18.1 15.6 18.0 2.8 12.9 7.0 16.1 12.9 12.7 15.9 8.5 11.4 10.9 16.4 10.6 8.5 11.2 13.1 9.5 10.0 22.1 13.1 12.1 15.6 11.2 9.3 14.0 9.2 17.6 15.0 10.3 15.0 15.3 13.4 9.4 4.8 13.4 11.9 18.5 12.3 14.9 16.8 7.4 11.9 14.0 15.0 12.8 28.3 28.9 31.8 7.1 25.2 20.8 18.0 18.3 18.7 18.9 18.9 25.8 19.6 40.9 13.4 20.8 13.7 26.1 28.6 19.6 30.2 24.6 17.3 29.4 19.8 20.0 12.2 22.3 21.9 19.0 13.5 20.9 16.5 23.3 25.3 22.9 24.1 18.9 23.5 29.9 26.4 24.4 20.0 19.2 26.1 40.5 31.8 14.3 16.5 37.2 24.2 23.8 29.4 20.2 8.3 21.8 22.9 17.4 37.0 22.6 28.3 15.6 23.9 23.3 24.8 43.6 19.3 17.3 17.2 0.3 1.4 1.5 1.5 1.6 1.7 1.9 1.3 1.3 1.1 1.9 1.8 1.8 1.0 2.3 1.5 3.4 1.1 1.4 12.5 12.8 18.1 15.6 10.9 16.4 9.5 10.0 9.3 4.8 12.3 12.8 26.8 25.6 34.3 54.2 32.7 19.9 11.2 13.3 27.9 42.0 27.7 25.3 45.9 14.3 25.0 9.2 41.7 19.7 32.4 15.7 1.9 15.7 35.4 26.8 36.0 29.7 20.4 23.5 86.7 15.5 13.5 24.4 23.0 28.6 17.7 54.1 21.8 16.8 19.1 52.2 84.3 18.9 12.2 22.6 12.3 17.7 33.8 19.5 5.4 51.5 28.6 24.6 32.0 68.9 76.5 18.0 13.3 48.5 30.3 18.9 14.0 14.7 33.0 30.8 19.7 35.5 24.8 62.8 49.0 29.2 23.3 15.7 29.3 32.5 21.6 13.2 ZBTB18 "C2H2-171, RP58, TAZ-1, ZNF238" ENSG00000179456 "Zinc finger and BTB domain containing 18" Q99592 1 244048939-244057476 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 172.8;skeletal muscle: 85.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 51.8;Muller glia cells: 52.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.3" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 217.5" "HPA024656, HPA074019" Enhanced Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoplasm, Nuclear speckles" "HPA024656: , HPA074019: " "unprognostic (3.48e-3)" "unprognostic (9.17e-3)" "unprognostic (3.69e-3)" "prognostic favorable (1.34e-4)" "unprognostic (6.83e-2)" "unprognostic (4.52e-2)" "unprognostic (2.13e-1)" "unprognostic (1.15e-2)" "unprognostic (1.15e-2)" "unprognostic (8.43e-2)" "unprognostic (1.01e-2)" "unprognostic (2.60e-1)" "unprognostic (6.28e-2)" "unprognostic (9.37e-2)" "unprognostic (2.07e-2)" "unprognostic (6.54e-3)" "prognostic favorable (6.78e-6)" 9.8 6.3 36.2 14.9 45.4 28.2 9.0 172.8 57.5 7.4 20.3 9.2 13.2 7.2 18.5 5.8 8.6 7.4 12.2 66.1 13.5 11.9 19.0 10.0 18.2 18.0 18.1 7.2 24.6 6.2 4.9 9.4 24.7 10.1 10.8 42.2 10.6 11.5 85.5 8.3 14.6 6.1 19.0 20.2 11.4 22.3 18.9 41.9 8.4 37.5 15.7 10.0 5.4 29.8 23.7 8.2 31.2 1.2 4.0 4.1 21.7 13.0 9.6 20.5 12.4 6.3 18.7 17.9 1.2 25.2 6.6 2.4 20.1 6.4 25.5 6.4 17.7 3.0 3.1 3.0 6.3 3.8 9.1 3.5 5.3 12.3 7.7 24.7 22.5 19.3 2.3 7.5 24.5 0.3 31.4 15.2 16.1 7.3 3.6 9.1 21.2 5.1 13.1 8.0 45.8 44.6 5.4 0.2 14.8 13.0 0.4 27.2 33.7 10.5 12.9 6.5 28.0 3.2 0.4 7.0 10.6 11.6 21.6 0.1 0.2 1.3 0.1 0.3 0.1 0.6 0.2 0.2 0.3 0.9 0.5 0.3 2.3 0.1 0.6 0.9 0.2 0.1 36.2 45.4 172.8 57.5 66.1 13.5 18.0 18.1 24.7 19.0 18.9 29.8 18.5 9.6 18.5 37.2 16.2 11.2 3.3 5.0 8.0 6.1 32.6 6.1 22.2 8.6 10.0 18.4 12.5 1.5 8.2 10.5 0.0 4.5 3.8 18.2 3.3 15.3 19.3 0.0 51.8 5.1 2.0 3.8 10.7 11.0 6.3 5.1 12.8 44.3 6.1 6.7 19.8 16.1 18.3 25.4 26.7 5.0 2.1 16.1 3.6 15.0 13.9 52.1 2.1 21.6 20.8 8.5 7.9 4.9 2.2 5.2 6.6 12.0 17.4 27.6 13.1 10.9 6.2 9.8 7.7 8.7 19.7 1.0 7.2 1.7 14.8 4.2 ZNF821 ENSG00000102984 "Zinc finger protein 821" O75541 16 71859680-71895336 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 21.2" "Cell type enhanced" "Detected in many" "Early spermatids: 143.0;Spermatocytes: 79.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 9.5;naive B-cell: 13.4;T-reg: 5.6" "Group enriched" "Detected in many" 9 "B-cells: 13.4;T-cells: 5.6" "Cell line enhanced" "Detected in many" "AF22: 13.2;SCLC-21H: 13.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036372, HPA042742" Enhanced Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 21: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Nuclear speckles" "HPA036372: AB_10669790, HPA042742: AB_2678140" "unprognostic (3.16e-1)" "unprognostic (1.77e-1)" "unprognostic (6.50e-2)" "unprognostic (1.12e-2)" "prognostic favorable (1.20e-4)" "unprognostic (1.69e-2)" "unprognostic (2.28e-2)" "unprognostic (7.72e-2)" "unprognostic (5.25e-2)" "unprognostic (3.04e-2)" "prognostic favorable (4.27e-5)" "unprognostic (2.83e-2)" "prognostic favorable (6.32e-10)" "unprognostic (1.82e-2)" "unprognostic (1.79e-1)" "unprognostic (7.97e-2)" "unprognostic (1.02e-1)" 2.1 2.8 5.4 1.5 5.7 2.5 3.3 9.8 6.0 6.0 2.9 2.8 1.4 4.4 7.5 2.6 3.1 2.6 2.8 5.7 6.7 4.0 1.8 2.9 4.4 5.2 5.0 4.9 2.3 4.1 8.9 1.7 5.3 4.2 3.4 9.3 3.3 3.3 3.6 5.3 4.3 1.9 4.7 3.9 2.5 21.2 5.8 3.3 4.2 4.1 5.4 2.0 4.2 4.8 1.1 0.9 13.2 6.4 2.6 3.3 2.2 1.4 3.0 2.9 4.6 1.9 0.8 2.5 2.3 2.6 3.2 1.9 4.4 2.0 3.5 3.9 5.0 0.5 0.8 0.8 1.6 0.9 2.8 2.9 3.2 2.0 1.2 5.0 2.3 0.6 1.7 1.8 3.2 3.3 1.5 0.9 5.2 3.9 0.6 6.0 2.8 4.5 3.3 0.4 13.2 6.3 1.8 1.1 1.5 5.6 4.5 3.0 4.5 3.1 3.2 1.1 0.9 4.4 2.4 10.2 1.0 2.5 3.0 0.0 0.5 0.4 2.0 0.0 1.8 9.5 2.1 1.5 0.9 13.4 1.3 0.5 0.4 1.0 0.5 0.0 5.6 0.8 5.4 5.7 9.8 6.0 5.7 6.7 5.2 5.0 5.3 4.7 5.8 4.8 7.4 0.0 4.2 13.7 28.7 8.0 8.7 7.2 23.3 41.8 15.2 12.4 1.2 11.5 4.9 16.5 45.9 5.8 11.8 23.5 21.5 9.7 143.0 8.5 11.5 8.4 23.4 6.1 28.3 4.8 5.2 7.7 29.0 14.8 9.5 13.5 12.5 1.8 7.9 32.0 30.4 11.3 6.1 10.6 13.4 57.4 12.5 10.3 3.6 8.4 3.7 25.8 9.2 22.1 13.7 6.2 16.7 12.4 22.6 8.0 42.8 10.8 4.7 51.6 13.1 6.3 9.2 79.4 20.8 16.1 7.5 6.2 15.4 6.3 7.7 4.3