Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" AAGAB "FLJ11506, p34" ENSG00000103591 "Alpha and gamma adaptin binding protein" Q6PD74 15 67200667-67255195 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039371, HPA040174" Supported Supported "Nuclear speckles,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear speckles, Cytosol" "HPA039371: AB_10805476, HPA040174: AB_10805605" "unprognostic (1.48e-2)" "unprognostic (1.50e-1)" "unprognostic (8.25e-2)" "unprognostic (3.27e-2)" "unprognostic (1.06e-1)" "unprognostic (3.10e-2)" "unprognostic (2.84e-2)" "unprognostic (4.52e-2)" "unprognostic (9.10e-2)" "unprognostic (5.28e-2)" "unprognostic (1.24e-1)" "unprognostic (2.10e-1)" "prognostic favorable (1.36e-4)" "unprognostic (9.88e-2)" "unprognostic (3.05e-1)" "prognostic unfavorable (9.48e-4)" "unprognostic (1.53e-1)" 15.1 19.1 10.5 19.2 13.3 19.8 22.5 7.2 14.5 17.9 12.7 27.8 15.8 14.8 25.9 20.5 16.5 18.5 15.8 12.9 15.7 27.4 18.1 15.6 19.9 9.8 11.5 8.0 17.0 35.2 19.0 15.8 11.5 18.8 33.8 22.1 15.4 20.5 32.8 12.9 19.5 21.2 9.5 15.4 23.9 21.9 15.7 29.9 33.0 23.0 25.9 27.5 13.2 12.2 49.7 89.9 63.2 64.8 60.0 49.3 31.1 51.4 74.7 60.6 68.7 66.8 52.9 48.1 51.1 52.9 74.4 98.2 129.9 59.4 62.9 65.0 62.0 46.2 63.2 26.8 66.0 78.8 51.2 48.6 80.6 45.8 94.3 41.0 47.8 59.7 96.5 63.7 60.2 61.3 47.6 32.7 53.1 61.7 31.5 53.1 81.1 57.7 55.9 116.1 89.7 57.3 60.7 44.0 75.7 54.7 71.5 59.2 51.7 54.2 64.5 50.0 73.0 33.7 119.3 69.2 52.7 71.8 55.4 56.4 27.0 28.2 31.3 35.4 36.2 22.0 28.2 29.7 33.2 17.3 23.7 25.0 14.6 42.7 38.1 25.4 37.3 30.2 10.5 13.3 7.2 14.5 12.9 15.7 9.8 11.5 11.5 9.5 15.7 12.2 10.8 3.2 7.7 26.1 19.0 12.0 18.8 19.4 15.9 13.4 17.8 10.3 12.9 4.3 19.0 27.6 27.1 16.3 8.8 33.4 17.6 28.6 14.6 14.5 11.6 12.0 15.7 10.9 45.4 31.2 14.8 14.1 22.4 18.0 10.8 8.2 8.2 12.7 17.0 18.5 33.1 17.3 14.2 15.5 8.4 8.6 7.8 11.6 7.2 30.0 21.3 14.4 16.5 26.2 31.9 25.3 20.9 11.3 15.5 22.9 15.3 19.1 20.5 19.4 13.1 10.5 10.2 43.0 33.8 17.6 13.8 16.6 17.8 25.3 15.7 24.5 ABHD17A "C19orf27, FAM108A1, MGC5244" ENSG00000129968 "Abhydrolase domain containing 17A, depalmitoylase" Q96GS6 19 1876810-1885496 "Enzymes, Predicted intracellular proteins, Transporters" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 338.2;NK-cells: 383.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 90.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043270, HPA047226, HPA069225" Uncertain Approved "Nuclear speckles,Vesicles" NA NA "Cluster 37: B-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "Nuclear speckles" "HPA043270: AB_2678401, HPA047226: AB_2679991, HPA069225: " "unprognostic (3.77e-2)" "unprognostic (1.85e-1)" "unprognostic (3.57e-2)" "prognostic favorable (1.73e-4)" "unprognostic (3.70e-2)" "prognostic favorable (6.46e-4)" "unprognostic (1.69e-2)" "unprognostic (1.92e-2)" "unprognostic (5.09e-1)" "unprognostic (1.44e-1)" "prognostic favorable (1.76e-5)" "unprognostic (1.29e-2)" "unprognostic (1.85e-3)" "unprognostic (1.17e-1)" "unprognostic (2.71e-1)" "unprognostic (3.17e-1)" "unprognostic (1.60e-2)" 49.8 51.5 61.3 8.8 50.0 13.4 44.1 53.0 104.9 43.9 16.0 50.3 13.6 46.5 2.1 63.6 42.3 4.1 79.9 70.8 36.6 47.3 42.9 52.7 10.7 66.9 54.2 41.7 42.9 7.5 45.1 11.6 60.6 52.5 2.0 1.9 40.4 8.2 56.9 73.3 41.8 3.2 56.3 69.3 45.4 33.4 61.4 8.6 43.0 10.7 3.9 45.3 45.9 56.9 43.0 14.7 6.0 16.7 7.8 9.6 32.5 28.6 8.8 8.4 7.7 7.4 7.5 21.1 11.3 8.3 1.9 26.9 3.0 11.8 1.2 48.9 61.8 15.9 6.7 19.2 10.7 16.4 50.9 10.5 8.8 4.9 3.4 5.5 16.2 20.6 27.6 23.9 6.1 24.1 28.3 31.0 31.2 8.3 32.3 32.8 14.3 32.0 5.9 9.4 19.4 43.9 14.8 16.0 29.8 2.4 16.6 28.3 31.3 9.4 21.4 38.1 28.3 90.8 58.8 18.2 20.6 21.0 15.5 1.6 1.0 4.2 5.2 0.6 3.8 3.7 2.3 3.5 1.0 1.4 2.5 2.7 1.1 3.1 0.6 1.0 2.4 0.9 61.3 50.0 53.0 104.9 70.8 36.6 66.9 54.2 60.6 56.3 61.4 56.9 125.3 3.2 5.8 13.4 35.6 32.2 21.5 10.4 12.5 41.2 43.9 35.6 4.0 24.3 12.1 14.7 39.6 77.8 338.2 61.8 9.8 31.0 6.4 28.4 43.7 67.6 30.5 22.3 12.8 37.8 43.2 29.8 29.6 37.8 10.2 31.6 65.0 21.5 66.3 55.5 12.5 34.9 12.2 36.1 28.7 6.4 30.1 42.8 26.6 19.7 35.0 66.0 383.1 5.0 63.1 42.7 31.9 36.5 58.7 25.9 38.6 19.5 7.5 35.5 13.1 31.0 44.1 16.3 20.7 21.2 45.9 65.7 117.1 66.1 34.0 32.3 AC023055.1 ENSG00000257390 "Novel protein" 12 55757275-55827546 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 9 "testis: 8.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Alveolar cells type 2: 6.3;granulocytes: 2.5;Respiratory ciliated cells: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "SK-MEL-30: 3.0" "HPA017653, HPA030902, HPA030903" Uncertain Approved "Nuclear speckles,Cytoplasmic bodies" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 74: Testis - Spermatogenesis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 11: Alveolar cells - Smell perception" "Nuclear speckles" "Cytoplasmic bodies" "HPA017653: AB_1847799, HPA030902: AB_10669872, HPA030903: AB_10964180" "unprognostic (8.84e-4)" "unprognostic (2.25e-1)" "unprognostic (8.19e-2)" "unprognostic (1.16e-1)" "unprognostic (1.60e-1)" "unprognostic (7.17e-2)" "unprognostic (1.55e-3)" "unprognostic (1.86e-1)" "unprognostic (6.30e-2)" "unprognostic (3.79e-2)" "unprognostic (3.05e-2)" "unprognostic (2.16e-2)" "unprognostic (1.16e-5)" "unprognostic (6.36e-2)" "unprognostic (1.71e-1)" "unprognostic (1.22e-1)" "unprognostic (4.37e-3)" 0.4 0.1 0.0 0.1 0.2 0.5 0.1 0.1 0.2 0.0 0.2 0.1 0.2 0.0 0.3 0.2 0.1 0.4 0.2 0.1 0.1 0.3 0.2 0.1 0.4 0.3 0.2 0.0 0.1 0.3 0.0 0.0 0.3 0.2 0.3 0.9 0.1 0.1 0.2 0.2 0.4 0.0 0.0 0.1 0.2 8.9 0.7 0.0 0.0 0.0 0.2 0.3 0.1 0.3 0.1 0.0 1.2 1.7 1.1 0.0 1.3 0.8 0.6 0.1 0.5 0.5 0.4 1.3 0.2 0.7 0.4 0.7 1.0 1.2 0.5 0.0 1.2 0.9 0.3 0.5 0.5 1.4 1.0 0.2 0.0 0.5 0.2 0.0 0.1 0.7 0.6 0.0 0.2 0.0 0.7 1.0 1.9 1.4 0.0 1.1 1.4 0.8 0.7 0.6 1.6 0.5 0.5 2.1 3.0 0.5 0.4 0.4 0.0 0.0 0.1 0.2 0.3 0.0 1.1 0.9 0.3 0.2 0.2 1.2 0.4 1.4 1.1 0.8 0.7 1.9 1.3 0.7 1.1 1.3 0.9 1.3 0.2 1.8 2.0 0.6 1.8 1.4 0.0 0.2 0.1 0.2 0.1 0.1 0.3 0.2 0.3 0.0 0.7 0.3 0.1 6.4 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 1.3 0.0 0.0 0.1 0.5 0.0 0.0 0.3 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.3 2.5 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 AC091959.1 ENSG00000275740 "Novel readthrough transcript" 5 146203550-146339251 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "testis: 6.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA035944, HPA036422" Approved Approved "Nuclear speckles" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nuclear speckles" "HPA035944: AB_10670672, HPA036422: AB_10669987" "unprognostic (6.42e-2)" "unprognostic (7.72e-4)" "unprognostic (2.05e-2)" "unprognostic (4.95e-2)" "unprognostic (1.51e-2)" "unprognostic (1.13e-2)" "unprognostic (3.24e-2)" "unprognostic (8.78e-2)" "unprognostic (1.42e-1)" "unprognostic (3.61e-2)" "unprognostic (1.17e-1)" "unprognostic (3.77e-3)" "unprognostic (1.57e-1)" "unprognostic (2.31e-1)" "unprognostic (1.56e-2)" "unprognostic (2.12e-2)" 0.5 0.5 0.2 1.4 0.6 2.4 0.5 1.9 0.8 1.0 0.8 0.6 1.5 0.5 0.0 1.2 1.0 0.4 0.6 0.4 1.0 0.5 0.4 0.7 1.3 0.4 0.3 1.3 0.7 0.9 0.0 0.9 0.3 0.5 0.7 0.7 0.9 0.6 0.6 0.3 1.1 1.0 0.0 0.7 0.9 6.7 0.6 1.8 1.5 0.7 1.2 0.8 0.1 0.8 7.2 11.4 5.6 5.5 1.7 1.7 5.0 8.9 5.4 10.4 10.7 12.4 5.9 8.6 5.3 4.8 6.6 5.5 8.2 7.9 8.9 16.0 4.5 10.0 5.5 1.3 1.2 12.0 9.5 2.4 1.0 9.9 6.1 1.7 3.3 3.2 13.1 5.4 3.3 3.7 9.6 0.0 5.1 3.2 7.4 9.6 10.8 4.8 0.7 9.2 5.6 3.9 12.9 2.9 4.0 1.9 9.3 1.7 6.8 5.8 6.7 6.9 8.9 6.4 14.9 13.4 6.3 6.9 6.6 18.2 7.0 14.5 10.4 7.2 11.6 10.3 9.5 8.2 7.5 12.2 10.0 9.9 10.3 10.4 12.0 10.2 9.3 7.8 0.2 0.6 1.9 0.8 0.4 1.0 0.4 0.3 0.3 0.0 0.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 ADAL ENSG00000168803 "Adenosine deaminase like" Q6DHV7 15 43330672-43354569 "Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 81.3;Rod photoreceptor cells: 84.8;Spermatocytes: 99.5;Spermatogonia: 82.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039879, HPA048175, HPA058795" Approved Approved "Nucleoplasm,Nuclear speckles,Vesicles" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "Nuclear speckles, Vesicles" "HPA039879: , HPA048175: AB_2680298, HPA058795: " "unprognostic (1.65e-2)" "unprognostic (1.53e-3)" "unprognostic (9.80e-2)" "unprognostic (3.15e-3)" "unprognostic (2.46e-3)" "unprognostic (1.86e-1)" "unprognostic (2.00e-1)" "unprognostic (5.83e-2)" "unprognostic (5.90e-2)" "unprognostic (2.68e-1)" "unprognostic (6.85e-3)" "unprognostic (1.69e-1)" "prognostic favorable (7.64e-9)" "unprognostic (2.37e-3)" "unprognostic (8.77e-2)" "unprognostic (5.31e-2)" "unprognostic (2.44e-2)" 6.2 6.6 6.7 4.2 7.1 4.4 5.9 7.6 9.6 3.6 10.2 5.7 5.8 4.3 8.4 4.1 3.3 3.8 20.9 6.3 7.4 11.9 8.2 3.5 4.8 6.7 7.2 3.6 3.6 10.4 6.1 2.7 7.0 6.2 4.8 21.2 4.2 6.4 20.4 2.6 4.6 4.7 6.9 3.8 4.0 11.1 7.1 5.4 10.9 23.4 4.8 4.6 3.0 7.4 6.8 3.4 13.3 15.1 5.5 7.1 6.3 8.1 8.2 12.6 19.3 14.2 3.5 8.0 13.0 8.9 16.7 7.5 0.0 5.7 10.8 8.5 8.0 19.0 23.1 12.0 6.9 0.0 14.8 9.1 10.3 8.5 8.7 8.1 2.7 19.4 21.1 16.2 13.2 4.6 12.3 9.7 5.5 7.8 4.6 15.9 19.9 12.7 11.0 4.1 16.3 11.6 13.1 11.7 12.4 7.2 12.5 12.5 3.7 21.9 10.6 16.6 16.5 16.6 29.9 3.4 12.2 21.2 18.1 5.9 1.4 3.8 2.4 2.0 1.8 2.0 2.2 1.9 2.0 1.6 2.3 2.9 1.1 2.3 1.9 2.9 4.5 1.3 6.7 7.1 7.6 9.6 6.3 7.4 6.7 7.2 7.0 6.9 7.1 7.4 5.9 9.6 10.3 32.7 10.0 7.0 7.4 9.3 7.4 40.7 9.2 9.9 51.2 10.0 6.9 18.4 81.3 7.1 13.3 7.0 58.7 8.9 17.6 10.6 10.3 8.2 7.7 19.1 24.4 8.5 7.0 10.4 5.1 6.8 7.6 15.7 11.0 30.8 8.9 42.1 26.7 7.2 10.2 8.8 7.0 12.7 9.6 8.9 8.8 10.3 5.4 35.5 24.7 19.1 18.3 5.7 1.3 8.6 6.9 7.1 13.0 29.0 10.9 84.8 6.6 11.6 7.3 99.5 82.5 8.8 4.4 2.6 7.0 12.6 11.6 4.4 ADAM33 "C20orf153, dJ964F7.1, DKFZp434K0521" ENSG00000149451 "ADAM metallopeptidase domain 33" Q9BZ11 20 3667965-3682246 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" Asthma "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 280.4" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 40.8;Fibroblasts: 45.2;Leydig cells: 22.7;Microglial cells: 18.7;Smooth muscle cells: 17.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 82.4;ASC TERT1: 104.9;BJ: 38.5;BJ hTERT+: 64.7;fHDF/TERT166: 38.9;U-2197: 50.9" "Region enhanced" "Detected in single" "cerebral cortex: 1.0" "Low region specificity" "Detected in all" "HPA067152, HPA071758" Approved Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear speckles" "HPA067152: AB_2685791, HPA071758: " "unprognostic (1.10e-1)" "unprognostic (3.02e-2)" "unprognostic (2.24e-2)" "unprognostic (3.35e-3)" "unprognostic (4.39e-3)" "unprognostic (7.43e-4)" "unprognostic (7.14e-3)" "unprognostic (1.67e-1)" "unprognostic (1.78e-3)" "unprognostic (1.28e-1)" "unprognostic (1.26e-1)" "unprognostic (3.56e-1)" "unprognostic (2.75e-11)" "unprognostic (1.05e-2)" "unprognostic (1.92e-1)" "unprognostic (3.21e-5)" "unprognostic (3.10e-3)" 53.3 3.8 7.8 10.5 8.5 0.1 47.4 5.8 12.3 280.4 8.4 157.2 11.0 151.8 19.0 31.6 106.9 32.8 26.7 6.7 9.3 3.9 2.0 18.0 6.2 16.0 8.0 58.7 6.0 0.5 6.9 12.7 16.4 87.0 12.1 1.0 19.6 57.5 9.1 22.0 43.4 53.0 5.9 8.3 44.8 22.5 6.9 0.9 18.4 14.1 2.2 125.4 159.0 6.2 0.0 0.0 0.2 0.0 82.4 104.9 0.2 38.5 64.7 11.2 21.3 0.1 0.0 0.0 0.2 38.9 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.1 0.0 13.0 0.0 0.0 18.2 0.0 4.0 0.0 0.1 0.0 2.3 0.0 0.0 0.0 0.0 2.8 0.2 2.9 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.7 0.1 0.1 0.0 0.2 0.0 50.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.8 8.5 5.8 12.3 6.7 9.3 16.0 8.0 16.4 5.9 6.9 6.2 3.9 0.0 0.0 7.2 0.1 5.5 0.1 0.0 0.6 0.0 0.3 0.3 3.3 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.5 1.8 40.8 2.4 0.0 0.0 1.3 0.0 0.1 45.2 2.6 1.2 0.0 3.1 1.8 0.0 0.5 0.0 11.4 0.0 0.0 0.3 8.8 0.8 22.7 0.8 3.6 18.7 0.0 2.2 0.0 8.0 0.1 0.0 0.0 10.1 0.0 0.2 0.0 0.9 0.0 0.1 6.6 6.8 17.1 0.7 0.5 0.3 3.1 0.5 0.7 0.0 0.0 0.1 ADAMTS4 "ADAMTS-2, ADMP-1, KIAA0688" ENSG00000158859 "ADAM metallopeptidase with thrombospondin type 1 motif 4" O75173 1 161184302-161199054 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 116.8;ovary: 95.9" "Cell type enhanced" "Detected in many" "Adipocytes: 80.3;Endothelial cells: 115.5;Fibroblasts: 88.8;Oligodendrocytes: 56.0;Sertoli cells: 52.6;Smooth muscle cells: 313.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "plasmacytoid DC: 4.4" "Lineage enriched" "Detected in single" 8 "dendritic cells: 4.4" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 11.8;HUVEC TERT2: 14.4;SH-SY5Y: 7.9;TIME: 12.2;U-138 MG: 7.4;U-251 MG: 10.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025876, HPA051296, HPA068374" Uncertain Supported "Nuclear speckles" "Secreted to extracellular matrix" NA NA 11000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Nuclear speckles" "CAB025876: , HPA051296: AB_2681426, HPA068374: AB_2685978" "unprognostic (2.70e-2)" "unprognostic (8.10e-3)" "unprognostic (3.00e-3)" "unprognostic (2.75e-1)" "unprognostic (9.95e-3)" "unprognostic (1.19e-1)" "unprognostic (1.07e-1)" "prognostic unfavorable (5.00e-4)" "unprognostic (1.20e-2)" "unprognostic (9.59e-3)" "unprognostic (2.48e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (7.27e-7)" "unprognostic (1.10e-2)" "unprognostic (1.04e-1)" "unprognostic (1.44e-3)" "unprognostic (3.13e-2)" 116.8 9.8 6.1 16.3 31.5 0.7 43.4 31.1 19.2 16.4 5.8 18.2 0.8 15.0 0.2 6.2 34.6 14.3 53.6 8.1 15.2 26.0 8.7 50.3 1.6 38.2 29.6 95.9 9.0 2.1 13.0 3.2 31.6 16.9 2.0 1.5 5.2 0.5 13.3 5.0 9.4 10.5 28.3 1.8 22.8 1.8 26.2 1.1 21.3 0.4 0.3 31.8 12.2 48.0 0.0 0.0 0.2 0.1 6.4 4.0 0.6 5.4 0.2 0.5 3.0 0.2 0.2 0.2 4.4 1.7 0.0 0.1 0.0 0.0 1.9 0.1 0.3 0.2 0.5 1.3 0.6 0.0 0.1 4.5 0.0 11.8 0.1 0.0 14.4 0.1 0.2 0.3 0.4 0.1 0.0 0.2 5.3 0.0 0.0 0.1 5.1 0.1 0.0 0.1 0.1 7.9 0.0 0.1 0.1 0.3 0.2 0.5 12.2 7.4 0.1 0.4 10.8 0.2 0.1 0.1 2.2 0.1 0.1 0.5 0.1 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.4 0.2 0.0 4.4 0.2 0.1 6.1 31.5 31.1 19.2 8.1 15.2 38.2 29.6 31.6 28.3 26.2 48.0 80.3 0.0 4.1 0.0 0.2 31.2 3.2 0.0 2.2 2.2 8.6 5.5 5.5 0.0 0.6 0.0 0.0 0.3 0.5 0.2 0.0 0.3 0.0 0.3 13.0 115.5 0.0 0.0 0.4 0.0 0.3 88.8 0.5 0.5 0.0 0.3 43.2 0.9 1.0 3.3 0.1 0.0 0.0 1.0 32.6 0.2 0.3 3.2 35.6 2.8 1.0 0.5 0.0 0.0 56.0 0.0 0.0 1.2 0.7 9.8 0.0 0.1 0.0 1.0 52.6 21.2 313.7 2.7 0.6 2.7 19.0 0.4 3.7 1.6 0.3 7.7 AK6 CINAP ENSG00000085231 "Adenylate kinase 6" Q9Y3D8 5 69350984-69370013 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 185.9;Late spermatids: 275.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005361, HPA070217" Supported Supported "Nuclear speckles,Centrosome,Cytosol" No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear speckles" "Centrosome, Cytosol" "CAB005361: AB_2302969, HPA070217: " "unprognostic (5.47e-2)" "unprognostic (1.54e-2)" "unprognostic (1.48e-1)" "unprognostic (8.58e-2)" "unprognostic (8.73e-2)" "unprognostic (4.09e-2)" "prognostic unfavorable (9.54e-4)" "unprognostic (1.79e-1)" "unprognostic (3.41e-2)" "unprognostic (6.21e-2)" "unprognostic (2.55e-2)" "unprognostic (2.25e-2)" "unprognostic (1.14e-2)" "unprognostic (1.31e-1)" "unprognostic (1.84e-1)" "unprognostic (2.22e-1)" "unprognostic (2.55e-2)" 46.0 58.0 18.7 12.5 19.6 11.6 40.0 20.6 27.1 26.1 19.8 40.8 15.2 32.4 21.6 29.7 29.6 7.7 48.4 19.8 20.3 54.9 46.6 29.5 13.0 19.7 20.1 32.6 35.8 11.6 28.6 12.1 19.5 32.9 12.6 23.2 30.9 8.3 79.8 20.6 30.1 9.5 18.7 28.0 36.4 43.3 19.5 13.3 33.0 23.3 12.5 35.5 28.0 20.7 40.3 18.8 28.0 42.6 43.6 26.3 51.1 59.3 18.6 23.8 30.7 56.0 35.5 82.1 54.9 23.4 62.2 14.0 37.2 23.3 40.0 33.1 15.7 40.7 47.8 44.9 33.0 49.5 17.1 14.0 33.3 23.0 37.0 25.0 14.8 45.8 36.6 29.3 28.6 42.1 50.2 31.4 25.0 17.9 10.5 55.8 34.5 44.5 40.3 31.3 14.4 13.3 28.2 26.4 44.6 21.3 25.1 54.7 29.5 20.4 34.6 41.4 47.6 33.1 74.4 75.3 29.8 69.3 28.9 25.2 16.8 20.1 19.2 22.1 20.3 29.8 22.8 24.9 24.8 26.1 24.5 26.3 2.7 24.1 21.0 29.9 25.8 13.3 18.7 19.6 20.6 27.1 19.8 20.3 19.7 20.1 19.5 18.7 19.5 20.7 51.5 22.4 30.0 14.0 33.9 0.0 95.7 0.0 33.6 19.8 57.3 86.6 55.6 18.6 16.7 23.9 10.4 86.7 27.2 16.8 185.9 75.6 174.9 36.4 34.6 38.6 9.7 29.2 14.8 78.5 95.1 47.3 16.8 30.2 21.5 31.7 30.7 42.5 71.3 20.2 15.4 21.3 0.0 30.6 0.0 275.9 33.5 32.2 0.0 6.5 42.4 58.7 34.0 13.0 17.0 59.1 25.5 32.0 29.4 116.6 48.6 149.8 18.2 29.3 52.6 40.9 50.0 56.5 37.9 24.3 0.0 66.2 27.6 44.7 32.9 88.1 AKAP17A "721P, CCDC133, CXYorf3, DXYS155E, MGC39904, SFRS17A, XE7, XE7Y" ENSG00000197976 "A-kinase anchoring protein 17A" Q02040 X 1591604-1602520 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Theca cells: 131.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.5" "Lineage enriched" "Detected in single" 5 "granulocytes: 4.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043247, HPA051020" Supported Supported "Nuclear speckles,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 29: U-266 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" Cytosol "HPA043247: AB_10964776, HPA051020: AB_2681314" "unprognostic (4.55e-2)" "unprognostic (1.56e-1)" "unprognostic (1.74e-1)" "prognostic favorable (3.40e-4)" "unprognostic (5.38e-2)" "unprognostic (1.59e-2)" "unprognostic (9.73e-3)" "unprognostic (6.25e-2)" "unprognostic (2.09e-1)" "unprognostic (7.91e-3)" "prognostic favorable (2.42e-4)" "unprognostic (1.55e-3)" "prognostic unfavorable (3.52e-7)" "unprognostic (1.86e-2)" "unprognostic (2.71e-1)" "unprognostic (4.03e-2)" "prognostic favorable (1.11e-5)" 35.2 46.9 13.7 33.8 15.0 44.6 37.3 12.3 15.2 45.6 15.1 38.6 30.9 35.2 20.1 38.5 39.5 16.5 34.9 13.0 11.9 39.3 70.1 51.5 36.0 16.4 14.1 73.0 66.4 12.6 46.6 17.3 13.5 50.7 9.9 7.5 41.5 15.9 17.4 35.6 49.4 7.6 12.1 83.0 41.3 31.8 16.3 27.2 62.7 9.2 20.1 32.2 38.0 20.3 23.8 29.8 23.4 26.5 11.3 14.4 57.1 25.1 10.2 19.8 16.6 33.3 21.3 35.5 15.8 12.6 27.9 20.4 14.3 12.6 11.8 29.3 49.2 44.3 32.6 31.3 24.1 17.3 71.3 12.8 22.8 14.8 16.4 23.6 13.8 17.7 28.2 21.8 11.7 15.6 38.5 74.4 35.0 5.5 25.6 28.9 27.9 30.0 13.2 16.3 26.1 38.1 19.7 31.5 31.5 19.2 20.6 31.3 26.9 30.8 14.0 26.9 22.1 93.7 17.0 49.1 12.5 27.7 8.4 4.5 0.5 0.9 0.3 0.2 0.4 0.9 0.4 0.7 0.3 0.5 0.3 0.3 1.9 0.7 0.4 0.8 0.2 0.2 13.7 15.0 12.3 15.2 13.0 11.9 16.4 14.1 13.5 12.1 16.3 20.3 41.2 25.6 25.3 1.3 53.5 44.4 36.1 10.6 36.5 24.1 41.5 29.8 12.0 12.8 19.4 12.9 10.4 25.1 67.0 39.9 13.7 21.2 52.1 29.6 32.7 35.1 22.6 14.5 0.8 15.5 32.4 31.5 39.3 41.1 25.4 49.8 32.2 21.3 22.8 16.8 0.8 38.7 12.2 25.7 54.5 18.9 38.8 37.4 40.9 0.0 38.0 21.5 54.6 2.0 2.7 24.4 35.9 31.6 65.0 41.9 22.6 7.9 14.4 15.4 0.0 28.4 23.2 20.6 27.6 31.7 47.2 72.7 51.1 131.7 28.6 46.2 AKAP8L "HAP95, NAKAP95" ENSG00000011243 "A-kinase anchoring protein 8 like" Q9ULX6 19 15380050-15419141 "Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042485, HPA042546" Enhanced Supported "Nuclear speckles" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 6: Erythroid cells - Oxygen transport" "Nuclear speckles" "HPA042485: AB_2678019, HPA042546: AB_2678046" "unprognostic (9.52e-3)" "unprognostic (5.23e-2)" "prognostic unfavorable (3.49e-4)" "unprognostic (1.08e-2)" "unprognostic (3.25e-1)" "unprognostic (3.53e-2)" "unprognostic (1.38e-2)" "unprognostic (2.87e-2)" "unprognostic (1.08e-1)" "unprognostic (3.57e-2)" "prognostic favorable (8.04e-4)" "unprognostic (1.01e-2)" "prognostic unfavorable (1.08e-7)" "unprognostic (2.77e-1)" "unprognostic (1.07e-1)" "unprognostic (8.80e-2)" "unprognostic (2.34e-3)" 27.2 32.8 25.1 4.0 25.5 32.3 26.9 26.0 32.2 34.8 21.8 32.7 2.5 23.5 11.9 23.4 31.8 7.5 41.5 24.4 25.3 29.3 28.8 33.5 9.4 24.1 24.4 36.2 22.5 11.1 40.4 9.3 24.7 32.3 5.8 37.4 23.2 6.3 60.5 34.5 24.0 6.4 25.0 31.5 24.7 48.8 25.8 20.6 33.9 24.1 10.8 26.8 28.1 26.1 25.4 25.8 32.3 17.2 32.3 34.0 18.8 21.0 25.1 34.0 30.9 41.5 35.2 23.2 38.8 23.4 31.8 29.9 51.2 28.3 29.8 39.8 44.2 40.3 21.9 34.0 57.3 38.8 26.6 29.6 52.0 27.2 35.3 31.3 25.4 38.0 51.3 41.9 21.3 34.3 39.0 32.6 31.9 32.0 41.9 46.6 22.8 25.2 28.7 8.5 37.2 23.5 26.2 28.3 37.5 42.4 20.8 42.2 30.4 20.5 15.4 34.4 36.7 60.1 48.0 49.5 19.2 39.8 23.5 0.1 1.8 1.7 0.9 0.8 1.8 1.7 0.8 1.0 1.5 2.3 1.3 1.2 3.5 0.5 1.0 1.4 2.8 0.8 25.1 25.5 26.0 32.2 24.4 25.3 24.1 24.4 24.7 25.0 25.8 26.1 34.7 6.4 15.9 55.5 39.1 31.6 48.2 22.6 26.2 60.9 34.6 29.3 7.7 17.2 30.0 35.0 77.2 35.6 47.3 22.5 25.4 32.6 34.6 52.7 33.7 29.8 25.6 114.9 59.1 31.8 28.6 26.0 50.0 42.6 13.9 69.6 17.5 17.0 16.3 79.1 45.1 22.0 26.4 18.6 32.8 9.9 26.4 31.3 26.6 19.7 24.0 42.0 30.9 29.7 38.5 32.5 19.9 29.3 38.2 33.2 13.6 17.3 32.1 83.2 26.3 27.8 45.2 83.3 63.9 26.4 39.2 62.4 44.0 60.2 18.3 40.2 AL357075.4 ENSG00000288520 "Novel protein" G9CGD6 6 154159828-154510114 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 1.4;HMC-1: 1.0" "HPA028708, HPA028710, HPA049651" Uncertain Approved "Nucleoli,Nuclear speckles,Plasma membrane,Cytoplasmic bodies" NA NA "Cluster 3: HMC-1 - Innate immune response" "Nuclear speckles, Plasma membrane" "Nucleoli, Cytoplasmic bodies" "HPA028708: AB_10601916, HPA028710: AB_2732442, HPA049651: AB_2680841" 0.2 0.1 0.0 0.1 0.2 0.1 0.3 0.3 0.4 0.5 0.5 0.3 0.5 0.7 0.1 1.0 0.4 0.3 0.2 0.0 0.2 0.8 0.6 0.2 0.0 0.3 0.2 0.5 1.4 0.0 0.5 0.3 0.4 0.3 0.1 0.0 0.3 0.0 0.0 0.6 0.6 0.3 0.5 0.3 0.6 0.2 0.0 0.2 0.0 0.4 0.5 0.6 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 1.4 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.1 0.3 0.0 0.1 0.4 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.4 0.0 0.2 0.3 0.2 0.3 0.3 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AL669918.1 ENSG00000250264 "Novel protein, TAP2-HLA-DOB readthrough" 6 32813767-32838822 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 11.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 19.9;HDLM-2: 11.5;HEL: 9.8;U-698: 10.0" HPA001312 Approved Approved "Nuclear speckles,Endoplasmic reticulum" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Nuclear speckles, Endoplasmic reticulum" "HPA001312: AB_1080206" "unprognostic (6.13e-2)" "unprognostic (8.76e-3)" "unprognostic (4.62e-1)" "unprognostic (9.88e-2)" "unprognostic (1.99e-1)" "unprognostic (3.39e-2)" "unprognostic (1.72e-1)" "unprognostic (1.18e-1)" "unprognostic (1.08e-1)" "unprognostic (1.48e-1)" "unprognostic (1.09e-1)" "unprognostic (2.49e-1)" "unprognostic (8.73e-2)" "unprognostic (2.03e-1)" "unprognostic (1.33e-1)" "unprognostic (1.33e-1)" 1.7 1.0 0.4 11.8 0.4 1.4 1.0 0.7 0.5 1.5 0.1 1.6 2.0 1.4 0.0 1.4 1.1 0.6 0.6 0.5 0.5 0.6 0.5 1.9 5.9 0.6 0.4 0.6 0.4 0.4 1.5 0.2 0.6 0.7 1.0 0.0 2.8 0.0 0.4 1.0 5.0 0.4 0.8 7.0 4.4 0.6 0.6 0.7 1.1 0.0 1.3 1.1 1.2 0.9 2.4 2.9 0.0 0.8 1.6 1.8 0.6 0.7 0.3 0.0 0.7 0.0 3.3 19.9 1.7 0.4 0.2 6.2 2.1 2.8 0.7 11.5 0.4 9.8 2.8 0.3 0.5 0.0 1.3 0.0 0.9 0.6 0.2 0.0 0.0 2.1 3.8 2.4 0.1 0.7 1.6 1.1 0.3 0.0 3.8 4.0 0.6 6.3 0.1 0.0 0.3 0.4 2.2 6.1 1.6 0.0 4.6 1.0 0.0 1.4 2.0 0.5 1.0 1.8 4.7 10.0 1.0 4.2 0.4 0.7 1.8 3.7 1.5 1.7 1.9 4.5 1.6 2.2 3.4 4.5 1.2 2.6 4.1 1.3 3.0 3.1 2.5 3.3 0.4 0.4 0.7 0.5 0.5 0.5 0.6 0.4 0.6 0.8 0.6 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 ALMS1 KIAA0328 ENSG00000116127 "ALMS1 centrosome and basal body associated protein" Q8TCU4 2 73385758-73625166 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Cone-rod dystrophy, Deafness, Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 22.2" "Cell type enhanced" "Detected in many" "Early spermatids: 68.4;Excitatory neurons: 64.9;Late spermatids: 86.6;Oligodendrocytes: 92.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "RH-30: 32.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA035277, HPA043200" Enhanced Approved "Nuclear speckles,Centrosome,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear speckles, Centrosome" Cytosol "HPA035277: , HPA043200: AB_10796689" "unprognostic (2.86e-1)" "unprognostic (9.67e-2)" "unprognostic (2.58e-2)" "unprognostic (4.50e-3)" "unprognostic (1.36e-1)" "unprognostic (6.39e-2)" "unprognostic (2.91e-3)" "unprognostic (7.73e-2)" "unprognostic (1.02e-1)" "unprognostic (8.58e-2)" "unprognostic (4.78e-2)" "unprognostic (1.84e-1)" "unprognostic (3.43e-2)" "unprognostic (1.63e-1)" "unprognostic (7.85e-2)" "unprognostic (2.13e-1)" "unprognostic (1.94e-1)" 2.6 2.4 5.3 2.4 6.8 5.5 4.3 16.0 5.2 4.1 4.5 3.1 2.3 4.5 4.7 1.9 6.4 2.5 1.6 5.3 4.8 3.5 2.4 3.1 3.2 6.8 6.4 9.8 4.5 4.8 1.7 2.7 6.0 3.5 3.0 10.4 2.9 3.6 0.8 2.9 1.9 3.6 5.1 2.4 2.9 22.2 5.7 8.7 4.6 3.1 2.9 2.6 1.5 7.8 14.3 4.6 9.0 8.2 6.2 5.8 6.7 4.8 5.0 6.2 4.8 4.8 1.5 13.8 3.3 6.7 8.0 6.5 12.3 4.2 8.3 6.7 4.1 7.9 4.4 10.2 4.1 10.9 3.8 4.5 3.7 7.6 3.9 3.9 6.3 9.3 7.4 4.9 7.1 7.0 10.2 14.3 10.6 5.7 3.9 10.8 32.5 5.1 4.1 3.7 7.1 10.0 9.1 1.5 5.2 7.5 1.7 2.5 5.4 8.2 8.3 7.1 11.7 6.6 4.0 10.4 3.7 8.2 4.0 0.2 0.0 0.5 0.2 0.1 0.1 0.2 0.3 0.2 0.0 0.2 0.2 0.3 0.0 0.2 0.1 0.3 0.2 0.0 5.3 6.8 16.0 5.2 5.3 4.8 6.8 6.4 6.0 5.1 5.7 7.8 7.3 6.4 10.3 48.3 5.6 2.4 3.1 2.6 6.8 23.3 4.7 4.8 7.2 7.2 9.1 11.0 25.0 3.3 12.8 4.4 0.0 4.7 68.4 30.6 13.2 8.0 7.3 15.4 64.9 3.7 2.7 8.9 10.7 9.3 5.1 21.8 4.6 2.2 3.3 21.9 55.8 5.2 0.0 3.1 2.7 86.6 8.1 6.3 3.6 31.9 5.3 9.2 5.2 54.3 92.7 3.4 1.3 9.1 10.2 3.2 4.0 1.7 25.2 39.7 6.6 14.8 9.5 30.6 26.7 6.9 3.3 1.9 7.8 11.5 5.3 2.0 ALOX12 12S-LOX ENSG00000108839 "Arachidonate 12-lipoxygenase, 12S type" P18054 17 6996049-7010754 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Dioxygenase, Hydrolase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 34.6;esophagus: 49.4;vagina: 105.7" "Cell type enriched" "Detected in some" 6 "Macrophages: 17.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 4.5" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 5 "A-431: 25.5;HEL: 40.4" "Region enriched" "Detected in single" 5 "olfactory bulb: 4.4" "HPA010691, CAB019287, HPA064819" Enhanced Supported "Nuclear speckles,Vesicles,Cytosol" NA NA 49000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "Nuclear speckles, Vesicles" "CAB019287: , HPA010691: AB_1844756, HPA064819: " "unprognostic (3.61e-3)" "unprognostic (6.93e-2)" "unprognostic (7.17e-5)" "unprognostic (9.43e-2)" "unprognostic (6.06e-2)" "unprognostic (2.25e-3)" "unprognostic (2.45e-1)" "unprognostic (3.16e-1)" "unprognostic (3.02e-2)" "unprognostic (1.59e-2)" "unprognostic (3.96e-5)" "unprognostic (4.01e-3)" "unprognostic (2.25e-2)" "unprognostic (1.56e-1)" "unprognostic (2.87e-1)" "unprognostic (5.90e-2)" "unprognostic (3.47e-2)" 1.0 1.5 0.9 3.2 1.5 4.7 0.3 0.1 1.4 34.6 0.6 0.4 1.8 2.2 0.0 49.4 1.2 3.1 1.4 0.4 0.4 0.5 0.2 1.1 3.9 1.3 0.7 1.3 1.9 0.0 0.1 1.1 1.0 0.8 0.1 3.1 20.2 0.0 1.6 21.7 2.0 0.2 0.1 3.3 1.1 1.3 1.2 0.0 1.9 0.1 3.8 1.5 105.7 3.4 25.5 4.2 1.9 1.4 0.0 0.0 1.7 1.6 0.0 0.0 0.0 3.7 0.9 1.3 0.9 0.0 1.4 3.2 0.0 0.1 0.0 2.8 3.2 40.4 6.8 2.8 0.1 0.4 6.5 0.0 0.1 0.0 0.0 2.4 0.0 2.8 2.7 1.4 0.0 0.3 0.5 0.9 1.3 0.2 0.8 1.4 0.8 0.7 0.0 3.2 0.1 0.9 0.7 0.8 0.4 2.4 1.5 1.1 4.6 2.2 1.2 2.1 1.1 0.8 0.3 0.7 1.2 3.0 1.0 2.1 0.9 1.8 0.7 0.4 0.5 1.1 0.5 0.7 0.7 0.6 0.2 0.3 4.5 0.7 0.4 1.3 0.3 13.6 0.9 1.5 0.1 1.4 0.4 0.4 1.3 0.7 1.0 0.1 1.2 3.4 0.0 0.0 0.0 2.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.0 1.1 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 17.3 0.0 1.0 0.8 0.0 0.0 2.5 2.4 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 2.5 1.1 0.0 0.1 0.1 0.0 2.0 ALYREF "ALY, ALY/REF, BEF, REF, THOC4" ENSG00000183684 "Aly/REF export factor" 17 81887835-81891586 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 148.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016281, HPA019799, HPA061282" Supported Enhanced "Nuclear speckles" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Nuclear speckles" "CAB016281: AB_626667, HPA019799: AB_1844788, HPA061282: AB_2684464" "unprognostic (1.41e-1)" "unprognostic (1.09e-2)" "unprognostic (4.89e-3)" "unprognostic (5.35e-2)" "unprognostic (3.43e-1)" "unprognostic (2.13e-2)" "prognostic unfavorable (1.18e-4)" "unprognostic (2.77e-2)" "unprognostic (2.26e-1)" "unprognostic (2.55e-3)" "unprognostic (6.58e-2)" "unprognostic (8.07e-2)" "unprognostic (1.74e-3)" "unprognostic (2.05e-2)" "unprognostic (1.34e-1)" "unprognostic (8.65e-2)" "unprognostic (7.09e-2)" 39.0 30.0 19.2 50.2 19.6 148.9 34.9 20.2 22.9 33.1 17.7 37.4 32.9 35.1 17.1 57.6 31.3 19.6 37.8 19.8 20.0 37.7 29.6 36.0 62.4 19.6 20.7 32.4 26.9 21.3 28.9 32.1 20.9 30.0 24.3 9.4 30.3 15.9 61.5 45.7 34.5 21.1 20.9 44.7 31.6 72.7 19.8 65.7 30.6 21.2 48.8 35.7 36.4 22.1 263.7 237.8 165.5 164.6 34.4 44.8 213.8 130.0 68.0 257.0 161.0 269.4 173.7 291.4 100.8 104.9 155.6 150.5 241.9 137.5 111.7 111.8 425.9 210.8 151.2 295.1 68.6 341.4 183.0 46.1 61.8 155.3 62.0 37.8 155.5 204.6 275.9 175.2 97.2 279.8 721.2 587.2 231.3 152.0 254.2 472.3 206.1 155.1 54.1 152.1 229.8 299.0 123.9 304.8 110.4 89.9 222.1 343.3 103.9 275.1 270.9 130.0 443.2 201.8 107.3 377.6 143.7 217.0 238.2 0.3 1.1 0.1 1.5 1.2 1.0 1.0 1.1 1.0 1.2 1.2 0.3 0.8 0.2 0.9 1.1 2.2 0.6 0.6 19.2 19.6 20.2 22.9 19.8 20.0 19.6 20.7 20.9 20.9 19.8 22.1 68.4 0.0 16.0 1.3 22.9 34.9 22.9 7.5 9.1 11.0 24.7 32.5 13.0 11.5 8.4 20.2 0.0 9.8 59.0 16.1 1.9 5.2 2.3 52.9 49.0 23.4 12.6 43.3 1.7 8.4 23.1 24.9 17.3 53.7 15.2 39.1 8.9 14.8 17.9 5.0 1.7 24.3 6.1 13.9 33.8 3.2 3.4 31.3 14.2 3.7 12.7 21.5 8.2 2.5 5.0 10.5 10.1 4.1 46.4 33.1 7.4 4.3 8.4 7.6 0.0 27.9 30.6 16.5 8.8 22.6 43.0 16.6 27.6 38.2 21.9 31.6 ANKRD44 PP6-ARS-B ENSG00000065413 "Ankyrin repeat domain 44" Q8N8A2 2 196967017-197311173 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 36.5" "Cell type enhanced" "Detected in many" "B-cells: 153.3;Microglial cells: 390.7;NK-cells: 146.2;Oligodendrocyte precursor cells: 174.9;Oligodendrocytes: 199.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 46.4;HMC-1: 33.8;Karpas-707: 25.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030122, HPA056549" Approved Approved "Nuclear speckles,Mitochondria" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 57: B-cells - Immune response" Mitochondria "Nuclear speckles" "HPA030122: AB_10600980, HPA056549: AB_2683170" "unprognostic (3.64e-1)" "unprognostic (1.70e-2)" "unprognostic (1.05e-1)" "unprognostic (1.33e-1)" "unprognostic (2.63e-1)" "unprognostic (7.04e-5)" "unprognostic (1.97e-2)" "unprognostic (1.58e-3)" "unprognostic (2.27e-1)" "unprognostic (1.18e-1)" "unprognostic (8.25e-3)" "unprognostic (1.33e-1)" "unprognostic (1.33e-1)" "unprognostic (1.01e-1)" "unprognostic (1.29e-2)" "unprognostic (6.94e-2)" "unprognostic (3.67e-2)" 5.8 6.4 8.0 24.6 10.8 17.4 4.1 8.9 9.3 8.1 5.7 5.8 3.8 4.9 2.8 3.2 3.8 8.4 4.2 6.8 10.4 3.3 4.9 11.6 36.5 12.7 10.8 3.2 3.7 4.1 3.9 7.6 13.2 4.4 5.5 3.3 4.0 5.0 2.2 3.6 11.5 6.1 10.0 23.0 6.8 5.7 11.7 28.3 3.2 2.2 33.2 6.8 6.2 14.6 1.9 1.1 2.8 2.9 6.2 2.5 0.6 4.1 1.8 2.1 1.9 0.7 1.0 15.4 1.9 3.5 3.9 0.2 1.0 0.8 1.7 46.4 3.7 0.5 5.6 0.3 0.4 11.4 33.8 1.3 0.5 2.1 0.1 3.1 2.9 3.8 2.6 25.1 3.2 2.6 5.4 9.7 0.4 0.6 2.8 9.7 3.1 20.3 5.4 1.4 2.8 12.2 1.4 1.0 12.0 2.1 1.5 11.0 15.0 7.1 4.2 2.2 3.0 6.2 8.0 19.6 5.0 14.0 4.5 55.0 19.6 45.3 24.5 19.5 23.3 23.5 18.2 21.3 19.2 28.6 20.9 25.2 68.7 25.0 25.2 12.6 19.0 15.1 8.0 10.8 8.9 9.3 6.8 10.4 12.7 10.8 13.2 10.0 11.7 14.6 8.4 16.0 23.9 79.7 153.3 3.4 4.5 0.4 2.2 9.9 4.4 3.9 9.3 20.0 8.0 11.0 4.2 5.9 90.6 0.6 1.9 4.0 14.0 10.7 6.7 10.2 2.4 12.8 32.6 4.6 0.8 9.7 8.2 15.5 53.8 4.8 49.2 8.9 18.5 3.3 126.4 1.9 0.0 64.2 34.9 17.5 15.5 72.5 37.4 390.7 84.1 8.0 146.2 174.9 199.5 5.0 2.6 17.7 70.4 3.9 2.9 1.5 10.6 10.4 19.7 15.5 16.4 2.9 3.4 5.2 3.7 1.4 123.0 4.3 1.8 4.9 ANKRD55 FLJ11795 ENSG00000164512 "Ankyrin repeat domain 55" Q3KP44 5 56099680-56233330 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 8.3;liver: 3.1;lymphoid tissue: 3.6;testis: 9.8" "Cell type enhanced" "Detected in some" "Early spermatids: 161.3;Hepatic stellate cells: 41.7;Inhibitory neurons: 103.5;Late spermatids: 29.1;Spermatocytes: 59.3" "Cancer enriched" "Detected in single" 6 "testis cancer: 1.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "basophil: 22.9;eosinophil: 20.7;naive CD4 T-cell: 19.8" "Group enriched" "Detected in many" 74 "granulocytes: 22.9;T-cells: 19.8" "Group enriched" "Detected in some" 6 "HEL: 34.4;HMC-1: 17.1;NB-4: 22.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA051049, HPA061649" Uncertain Approved "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Nuclear speckles" Cytosol "HPA051049: AB_2681326, HPA061649: " "unprognostic (1.00e-4)" "unprognostic (1.58e-4)" "unprognostic (2.63e-1)" "unprognostic (1.93e-1)" "unprognostic (7.78e-4)" "unprognostic (1.46e-3)" "unprognostic (1.47e-1)" "unprognostic (1.33e-2)" "unprognostic (1.47e-1)" "unprognostic (1.16e-1)" "unprognostic (1.33e-1)" "unprognostic (1.40e-1)" "unprognostic (7.19e-6)" "unprognostic (2.56e-2)" "unprognostic (1.48e-1)" "unprognostic (3.25e-2)" "unprognostic (1.01e-1)" 0.4 0.1 2.2 0.7 3.0 0.7 0.1 0.0 2.4 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.2 0.3 0.1 0.9 8.3 0.4 3.1 0.3 3.6 4.1 4.6 0.1 0.0 0.0 0.2 0.6 5.2 0.0 0.2 0.4 1.0 0.0 0.0 0.4 1.3 0.1 3.3 1.6 0.3 9.8 7.8 3.2 0.2 0.0 2.0 0.3 0.1 0.9 0.2 0.3 0.1 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.7 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 34.4 0.2 1.3 0.0 1.6 17.1 0.0 0.1 0.0 0.0 0.1 4.2 0.1 2.9 1.1 0.0 0.0 0.0 22.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.9 1.7 0.0 2.3 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 2.0 0.4 22.9 0.2 20.7 0.1 0.1 0.0 0.0 4.3 0.0 0.1 0.0 19.8 0.8 2.0 0.0 0.1 0.0 1.0 2.8 2.2 3.0 0.0 2.4 0.9 8.3 4.1 4.6 5.2 3.3 7.8 0.9 0.3 0.0 0.0 0.3 0.3 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.5 1.5 0.0 0.0 0.0 0.4 1.4 0.0 0.0 0.0 161.3 0.4 0.8 2.2 0.0 0.0 1.3 0.2 0.3 0.6 0.5 7.5 2.5 0.1 41.7 0.6 0.7 0.0 103.5 0.0 0.0 3.2 1.9 29.1 0.6 1.4 1.8 1.0 0.9 0.9 3.1 18.6 1.0 0.0 0.0 0.7 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.2 59.3 0.6 0.0 0.0 1.2 3.9 0.5 0.0 0.2 ANXA9 ANX31 ENSG00000143412 "Annexin A9" O76027 1 150982249-150995634 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cholangiocytes: 61.5;Collecting duct cells: 12.9;Ductal cells: 21.2;Hepatocytes: 17.4;Proximal tubular cells: 44.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 1.6" "Group enriched" "Detected in many" 4 "dendritic cells: 1.6;granulocytes: 1.0;monocytes: 1.2" "Cell line enhanced" "Detected in many" "CAPAN-2: 40.6;Hep G2: 42.3;MCF7: 59.2;OE19: 47.8;T-47d: 139.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA028404, HPA028698" Enhanced Approved "Nuclear speckles,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles, Cytosol" "HPA028404: AB_10599190, HPA028698: AB_10600227" "unprognostic (4.06e-1)" "unprognostic (1.55e-2)" "unprognostic (3.15e-3)" "unprognostic (2.08e-3)" "unprognostic (2.93e-2)" "unprognostic (4.49e-2)" "unprognostic (1.84e-2)" "unprognostic (3.39e-2)" "unprognostic (1.08e-1)" "unprognostic (1.98e-1)" "unprognostic (2.10e-1)" "unprognostic (2.97e-1)" "prognostic favorable (8.74e-6)" "unprognostic (1.58e-2)" "unprognostic (1.11e-1)" "unprognostic (8.99e-2)" "unprognostic (1.72e-2)" 3.2 3.7 2.6 2.6 7.1 2.4 6.9 6.1 3.5 2.2 3.3 2.1 4.6 6.4 5.9 26.2 4.7 9.2 6.0 1.7 3.5 22.0 29.9 3.1 2.3 9.0 6.7 4.7 35.8 19.2 1.2 1.0 7.9 2.4 0.3 7.2 7.5 21.2 3.8 32.4 4.2 2.9 4.5 2.8 4.2 3.8 5.3 0.5 25.0 0.2 23.2 6.3 6.0 12.1 11.7 2.8 4.2 4.4 0.0 0.0 11.4 1.0 0.8 0.1 0.0 33.9 40.6 0.4 2.5 0.0 1.3 6.8 0.0 0.8 0.1 3.9 4.4 6.1 4.7 42.3 0.0 2.4 2.6 0.0 0.3 0.1 0.2 9.5 0.0 1.8 3.0 13.2 0.1 59.2 0.5 3.2 1.1 47.8 0.8 2.8 0.6 15.0 0.1 17.0 6.4 3.6 2.6 28.8 1.7 2.3 139.9 3.7 4.7 0.9 1.3 0.7 0.8 4.0 13.0 18.8 6.2 4.2 3.3 0.0 1.2 0.7 0.0 0.7 0.3 0.2 0.1 0.2 1.6 0.0 0.3 0.0 1.0 0.0 0.1 0.0 0.0 0.4 2.6 7.1 6.1 3.5 1.7 3.5 9.0 6.7 7.9 4.5 5.3 12.1 0.1 0.0 1.1 0.3 0.2 0.1 0.4 0.8 0.0 0.0 4.5 2.5 0.4 61.5 4.5 12.9 0.0 2.0 0.1 0.0 3.9 21.2 1.5 1.3 0.8 0.1 0.0 0.0 0.2 7.5 0.3 0.6 0.0 1.6 1.3 0.0 0.0 17.4 2.2 0.0 0.2 0.0 0.0 0.6 0.4 0.9 1.5 1.4 1.8 0.0 0.2 0.0 0.0 1.0 0.5 2.9 0.1 1.2 0.0 0.3 0.3 44.6 2.5 0.0 0.0 0.1 0.3 4.9 0.2 0.3 0.0 1.5 0.2 0.0 0.3 5.4 AP001273.2 ENSG00000284057 "Novel protein, C11orf54-MED17 readthrough" 11 93741664-93812378 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 9.5" "Cell type enriched" "Detected in single" 7 "Respiratory ciliated cells: 4.4" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA040511, HPA046619" Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "Nuclear speckles" Cytosol "HPA040511: AB_10795369, HPA046619: " 1.3 2.1 0.6 2.1 0.5 0.0 1.1 0.5 1.0 1.5 0.3 1.8 4.9 1.2 0.4 0.3 1.4 1.9 1.5 0.4 0.6 9.5 4.6 1.1 0.8 0.6 0.5 2.3 0.3 2.0 0.5 1.7 0.7 2.3 1.6 1.4 1.6 1.0 1.1 1.6 3.3 0.5 0.5 0.7 1.8 1.3 0.5 1.6 1.5 1.8 1.2 0.9 0.2 0.7 0.6 0.0 3.3 0.6 1.9 0.0 1.9 0.0 1.0 0.7 1.3 0.6 1.4 2.2 4.0 2.5 1.0 2.2 4.0 0.9 0.4 3.3 0.3 0.7 1.4 0.0 1.4 0.0 0.7 1.4 0.6 0.0 1.5 2.9 1.0 1.7 1.3 0.5 3.9 0.0 2.6 2.2 1.4 6.0 0.1 0.8 2.3 1.3 3.5 0.0 0.7 0.3 2.1 2.4 4.9 2.8 2.5 0.9 2.8 0.3 0.8 0.4 1.3 0.6 1.3 2.9 0.2 1.8 1.3 1.9 1.2 1.8 1.1 1.2 1.3 1.0 1.1 1.4 1.5 0.4 1.1 1.4 1.8 1.2 1.4 0.8 2.1 1.2 0.6 0.5 0.5 1.0 0.4 0.6 0.6 0.5 0.7 0.5 0.5 0.7 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AP5Z1 "KIAA0415, SPG48, zeta" ENSG00000242802 "Adaptor related protein complex 5 subunit zeta 1" O43299 7 4775615-4794397 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Protein transport, Transport" "Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 15.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035693 Supported Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear speckles" Nucleoplasm "HPA035693: AB_10960687" "unprognostic (1.64e-1)" "unprognostic (5.22e-2)" "unprognostic (3.01e-3)" "unprognostic (4.24e-2)" "unprognostic (2.43e-3)" "unprognostic (5.19e-1)" "prognostic unfavorable (1.35e-5)" "unprognostic (1.50e-1)" "unprognostic (2.03e-1)" "unprognostic (1.04e-1)" "unprognostic (1.10e-3)" "unprognostic (1.26e-2)" "unprognostic (5.32e-3)" "unprognostic (8.28e-2)" "unprognostic (1.71e-1)" "unprognostic (1.95e-2)" "unprognostic (2.22e-1)" 14.8 18.5 7.0 0.7 7.1 1.5 11.8 7.3 10.0 12.4 5.8 13.2 1.1 13.4 1.0 11.0 11.0 0.8 7.7 6.9 5.7 9.2 9.2 12.9 1.8 8.3 6.5 11.8 9.9 0.7 9.8 1.1 7.4 11.7 0.4 0.6 12.4 0.7 8.5 21.8 15.5 0.4 5.9 22.9 12.0 8.6 7.4 0.9 11.2 0.2 0.6 13.4 10.9 7.3 2.8 4.2 0.7 2.4 1.0 0.9 4.3 1.3 1.9 2.0 1.7 5.2 3.5 1.6 1.8 0.9 5.1 5.4 0.7 0.5 0.6 1.8 3.5 2.4 4.5 4.6 3.0 2.5 5.1 2.2 1.6 1.8 1.3 0.7 0.5 2.2 3.4 1.1 1.2 7.7 0.3 15.0 5.9 0.3 4.3 2.9 2.6 4.8 1.0 4.4 1.7 3.0 1.8 8.7 6.4 0.5 6.4 8.9 3.8 2.3 4.4 6.5 1.7 8.5 7.4 2.3 1.7 5.6 3.6 1.9 2.3 2.9 2.4 2.8 1.4 1.9 1.8 2.4 1.2 1.8 2.5 2.2 2.2 2.4 2.5 2.4 1.8 1.3 7.0 7.1 7.3 10.0 6.9 5.7 8.3 6.5 7.4 5.9 7.4 7.3 12.4 9.6 15.0 7.5 18.2 6.9 2.9 8.8 8.0 10.5 5.7 5.8 4.3 15.7 6.6 11.0 4.2 11.5 20.3 20.1 0.0 14.1 2.2 9.9 10.1 11.6 12.0 5.0 12.4 13.6 7.7 9.9 21.4 16.4 17.1 14.3 12.5 8.1 28.7 18.5 10.7 15.1 10.2 12.3 10.7 1.5 13.4 16.3 14.2 13.1 23.4 8.2 21.6 10.6 12.6 20.6 15.9 10.9 19.8 4.9 14.7 6.8 8.3 9.4 0.0 5.8 9.5 8.1 10.8 7.6 11.1 16.6 15.6 12.6 14.1 3.8 API5 "AAC-11, AAC11, API5L1" ENSG00000166181 "Apoptosis inhibitor 5" Q9BZZ5 11 43311963-43344529 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026598 Approved Enhanced "Nuclear speckles" NA NA 31000 "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nuclear speckles" "HPA026598: AB_1844927" "unprognostic (4.05e-2)" "unprognostic (1.57e-1)" "unprognostic (2.58e-3)" "unprognostic (6.08e-2)" "unprognostic (5.88e-2)" "unprognostic (3.46e-2)" "unprognostic (1.24e-2)" "unprognostic (1.73e-1)" "unprognostic (8.69e-3)" "unprognostic (1.45e-3)" "unprognostic (2.87e-2)" "unprognostic (1.35e-1)" "prognostic favorable (1.06e-4)" "unprognostic (5.03e-2)" "unprognostic (1.30e-1)" "unprognostic (1.69e-1)" "unprognostic (3.05e-2)" 37.6 33.1 29.2 43.4 31.1 35.3 45.7 38.5 37.4 39.3 25.9 44.3 42.8 42.1 34.5 44.6 36.6 32.4 28.2 32.0 30.6 49.1 57.7 34.8 53.5 29.2 28.5 35.1 45.9 46.6 19.0 29.9 30.8 40.4 46.6 44.1 39.0 39.5 37.1 40.0 45.5 46.6 32.8 40.3 41.1 26.8 29.9 62.1 51.4 35.9 57.2 44.2 27.6 38.6 90.2 93.0 119.4 75.2 82.7 82.4 82.9 83.8 89.4 116.3 110.2 69.4 38.8 106.4 67.2 90.2 86.9 107.7 143.2 99.7 160.6 122.4 134.9 96.5 53.0 60.8 74.8 165.6 88.9 64.2 104.6 59.0 102.9 72.4 98.9 65.8 160.3 93.9 82.1 57.0 141.2 71.1 214.6 111.1 86.0 145.2 126.3 85.3 89.5 103.8 95.5 64.2 100.7 88.7 81.4 88.4 109.1 76.6 86.5 102.0 78.3 139.8 144.5 77.5 122.7 172.1 88.8 95.0 62.3 61.3 47.3 51.5 66.5 64.5 75.1 61.7 64.8 69.3 62.1 60.4 66.3 68.7 9.9 116.3 67.3 40.0 61.4 88.4 29.2 31.1 38.5 37.4 32.0 30.6 29.2 28.5 30.8 32.8 29.9 38.6 26.4 16.0 27.3 30.0 35.9 43.8 16.6 21.6 47.3 23.8 27.8 17.8 14.4 31.5 28.0 20.2 10.4 30.4 31.8 20.1 31.3 21.3 13.6 23.5 25.8 26.2 24.0 48.0 40.2 19.7 30.4 28.3 35.2 28.2 32.3 25.9 22.1 48.0 26.3 28.6 33.5 27.5 12.2 33.6 28.8 6.5 18.6 30.0 32.0 27.2 41.7 21.1 17.5 25.1 45.4 24.9 19.8 20.3 44.2 24.0 29.4 37.3 20.8 19.0 6.6 28.9 31.1 28.4 26.6 43.1 51.9 38.9 33.8 26.6 31.4 19.2 ARHGAP18 "bA307O14.2, MacGAP" ENSG00000146376 "Rho GTPase activating protein 18" Q8N392 6 129576132-129710177 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 253.6;Respiratory ciliated cells: 265.3;Syncytiotrophoblasts: 212.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 395.8;LHCN-M2: 113.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031595 Approved Supported "Nuclear speckles,Plasma membrane,Cytosol" NA NA 1900000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 1: Thyroid gland - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "Nuclear speckles, Plasma membrane" "HPA031595: AB_10959905" "unprognostic (6.39e-2)" "unprognostic (1.60e-1)" "unprognostic (5.45e-2)" "unprognostic (5.49e-2)" "unprognostic (3.05e-1)" "unprognostic (3.17e-1)" "unprognostic (9.32e-3)" "unprognostic (1.25e-2)" "unprognostic (2.98e-2)" "unprognostic (3.12e-2)" "prognostic unfavorable (2.54e-4)" "unprognostic (4.08e-1)" "unprognostic (2.29e-3)" "unprognostic (2.22e-1)" "unprognostic (3.05e-2)" "unprognostic (5.52e-2)" "unprognostic (1.08e-1)" 20.5 37.2 3.4 13.0 2.5 4.3 13.4 2.4 2.8 14.9 15.1 14.8 24.8 6.7 20.2 6.0 28.3 15.4 6.0 2.9 4.1 28.4 6.3 28.7 9.4 4.7 5.7 6.0 33.2 14.2 6.7 20.8 4.3 9.9 15.0 2.6 14.6 8.4 10.6 4.0 27.3 10.6 3.5 9.0 27.9 8.3 6.4 6.1 23.0 13.0 7.9 12.6 4.1 3.7 8.6 18.8 1.9 2.6 17.8 25.0 15.1 64.0 48.8 27.7 18.5 10.0 14.1 7.1 30.6 43.2 8.8 11.0 13.4 20.9 51.3 7.0 5.7 46.7 13.8 57.3 25.4 6.9 395.8 15.9 3.2 50.4 44.7 57.8 79.8 0.0 25.3 17.4 113.1 2.3 0.1 6.8 2.0 16.0 4.5 0.3 8.5 13.7 84.6 4.8 0.0 0.1 5.3 8.8 32.3 9.3 9.7 8.1 61.6 28.8 4.1 2.3 51.8 7.8 6.0 4.8 9.7 12.7 40.9 12.0 5.1 13.5 4.9 5.8 3.1 2.9 2.5 5.5 4.8 1.7 0.4 2.6 3.9 2.5 3.2 11.8 2.8 6.0 3.4 2.5 2.4 2.8 2.9 4.1 4.7 5.7 4.3 3.5 6.4 3.7 139.5 57.7 33.3 1.6 13.0 13.0 17.7 15.7 10.8 0.7 53.4 14.7 4.1 17.2 39.5 38.6 2.1 92.7 31.0 19.0 150.6 48.2 20.7 176.1 5.8 89.2 13.1 10.9 16.8 120.5 24.9 45.3 63.2 35.7 253.6 34.7 11.0 5.0 110.4 0.0 23.1 22.1 63.1 48.4 112.4 21.2 3.7 163.9 7.2 43.1 23.9 16.4 28.8 12.5 2.2 102.4 25.0 1.2 26.4 18.5 69.8 31.7 265.3 0.9 26.3 38.9 32.5 10.6 1.1 11.2 12.9 212.3 35.9 69.1 31.3 19.1 ARHGAP42 "AD031, FLJ32810, GRAF3, TMEM133" ENSG00000165895 "Rho GTPase activating protein 42" A6NI28 11 100687288-100993941 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 31.6" "Cell type enhanced" "Detected in many" "Astrocytes: 102.8;Early spermatids: 74.7;Oligodendrocyte precursor cells: 226.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 30.2;RH-30: 20.4;RT4: 21.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039924, HPA060528" Uncertain Approved "Nuclear speckles,Cytosol" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 77: Retina - Visual perception" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" "Nuclear speckles" Cytosol "HPA039924: AB_10674428, HPA060528: AB_2684308" "unprognostic (1.04e-1)" "unprognostic (9.84e-2)" "unprognostic (3.21e-3)" "unprognostic (2.74e-1)" "unprognostic (1.50e-2)" "unprognostic (4.17e-2)" "unprognostic (1.13e-1)" "unprognostic (3.22e-1)" "unprognostic (1.30e-2)" "unprognostic (2.36e-1)" "prognostic unfavorable (9.29e-4)" "unprognostic (1.32e-1)" "unprognostic (1.75e-2)" "unprognostic (1.51e-1)" "unprognostic (2.65e-1)" "unprognostic (8.45e-2)" "unprognostic (1.03e-1)" 6.6 2.9 5.7 3.8 6.7 1.2 3.7 5.9 6.7 6.4 7.9 6.7 7.7 5.8 3.1 3.2 3.4 6.7 4.7 5.3 8.0 9.2 10.1 6.2 4.6 6.9 7.1 3.1 1.2 5.6 1.3 15.1 6.8 2.8 6.1 31.6 3.1 2.8 3.3 3.1 7.9 4.2 6.7 4.6 9.4 2.1 7.3 9.3 8.1 5.1 2.9 5.3 1.7 7.3 0.6 4.6 5.0 0.1 2.7 4.7 4.0 0.7 1.1 1.2 2.7 6.3 30.2 0.9 8.3 2.1 5.5 9.4 2.8 1.6 1.2 0.0 2.7 15.3 13.0 2.1 5.2 0.1 0.1 3.6 2.8 5.3 0.9 2.9 1.9 3.9 0.5 0.0 4.2 0.9 1.8 0.0 6.8 7.5 6.7 5.4 20.4 0.5 6.8 21.1 3.4 1.8 10.9 0.4 8.0 10.6 1.0 1.8 4.0 4.1 5.3 4.6 2.3 4.6 0.0 6.2 4.1 3.3 17.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 5.7 6.7 5.9 6.7 5.3 8.0 6.9 7.1 6.8 6.7 7.3 7.3 8.7 48.1 5.3 102.8 3.7 2.4 6.5 1.5 2.2 3.1 2.9 4.6 6.8 14.3 13.4 3.7 25.0 0.7 3.4 22.2 1.9 4.5 74.7 16.0 19.6 6.1 1.8 3.6 2.4 3.9 2.1 12.6 16.3 18.1 0.0 21.8 6.8 6.3 1.6 1.7 47.7 3.6 2.0 0.3 1.2 38.9 1.2 1.4 10.6 39.4 0.0 32.2 0.0 226.2 0.5 10.0 12.1 2.6 5.6 14.6 7.9 19.8 11.8 62.0 39.5 4.5 38.6 3.6 2.3 2.3 3.4 6.4 0.6 6.2 4.7 18.3 ARMCX5 "FLJ12969, GASP5" ENSG00000125962 "Armadillo repeat containing X-linked 5" Q6P1M9 X 102599168-102604159 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RH-30: 88.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000996 Approved Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 89: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 59: Non-specific - Transcription" "Nuclear speckles, Cytosol" "Plasma membrane" "HPA000996: AB_1078212" "unprognostic (7.71e-2)" "unprognostic (2.43e-2)" "unprognostic (1.20e-1)" "unprognostic (3.50e-2)" "unprognostic (1.54e-1)" "unprognostic (5.05e-2)" "unprognostic (4.07e-2)" "prognostic favorable (6.58e-5)" "unprognostic (1.12e-1)" "unprognostic (2.76e-2)" "unprognostic (2.83e-1)" "unprognostic (3.28e-3)" "unprognostic (1.17e-1)" "unprognostic (2.40e-1)" "unprognostic (1.17e-2)" "unprognostic (2.83e-1)" "unprognostic (5.24e-2)" 8.2 11.0 10.4 8.8 10.6 10.3 17.8 10.0 11.5 13.7 6.9 12.8 10.8 15.2 15.5 11.0 15.0 10.0 10.7 11.4 9.3 12.6 11.3 11.2 10.4 7.7 7.0 20.3 14.7 19.9 7.2 8.4 7.6 20.6 15.3 10.6 15.7 13.5 9.3 11.2 12.3 13.9 7.3 8.0 13.5 5.4 9.6 16.2 19.5 10.1 13.3 11.2 6.5 11.4 17.8 15.7 36.4 19.4 15.9 17.8 20.4 17.1 13.1 19.5 34.5 18.7 21.5 0.0 20.3 17.2 22.3 15.1 32.8 16.3 22.1 0.0 13.1 17.9 19.2 15.6 20.6 32.7 20.0 22.3 20.7 16.9 20.3 15.5 20.0 0.0 17.6 0.1 26.3 15.8 23.3 3.9 16.4 30.3 29.5 22.7 88.9 0.1 14.5 24.2 17.1 15.4 30.5 15.7 24.7 10.4 10.8 15.4 20.3 14.5 12.8 16.5 12.3 0.0 13.0 0.0 11.4 32.7 37.8 0.1 11.8 3.2 13.9 12.3 13.3 12.5 12.8 10.9 11.3 6.4 17.8 14.0 1.0 9.3 7.8 10.0 9.7 11.1 10.4 10.6 10.0 11.5 11.4 9.3 7.7 7.0 7.6 7.3 9.6 11.4 6.9 6.4 6.9 0.0 9.0 5.6 11.7 8.0 19.4 16.5 8.9 7.7 4.4 7.2 10.3 9.2 20.9 5.7 9.2 6.8 21.5 10.0 0.3 5.9 8.3 9.6 9.6 3.4 0.0 9.7 2.6 9.9 10.7 5.7 1.3 7.8 5.7 9.6 6.0 1.7 0.0 9.8 4.1 7.2 3.5 0.5 8.4 6.6 8.8 0.0 4.6 6.5 10.3 0.0 0.0 9.3 3.8 6.0 12.0 9.3 9.6 10.6 13.7 20.8 0.0 6.7 7.8 3.0 5.3 14.5 5.7 3.7 9.5 7.5 9.7 11.1 ATP6V0A1 "a1, ATP6N1, ATP6N1A, Stv1, Vph1, VPP1" ENSG00000033627 "ATPase H+ transporting V0 subunit a1" Q93050 17 42458844-42522582 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 130.7" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 294.0;Rod photoreceptor cells: 403.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022144 Enhanced Approved "Nuclear speckles,Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 58: Brain - Synaptic function" "Cluster 2: Karpas-707 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Golgi apparatus, Vesicles" "Nuclear speckles, Cytosol" "HPA022144: AB_1845189" "unprognostic (3.93e-2)" "unprognostic (2.02e-1)" "unprognostic (4.35e-2)" "unprognostic (2.22e-2)" "unprognostic (1.60e-2)" "unprognostic (8.69e-2)" "unprognostic (1.84e-2)" "unprognostic (8.82e-2)" "unprognostic (1.47e-1)" "unprognostic (1.85e-1)" "prognostic favorable (2.05e-4)" "unprognostic (3.25e-1)" "prognostic favorable (1.28e-4)" "unprognostic (3.07e-1)" "unprognostic (3.68e-2)" "unprognostic (2.62e-2)" "prognostic unfavorable (6.90e-4)" 17.7 28.2 30.6 18.0 35.2 21.5 16.3 16.8 42.7 13.4 0.0 22.1 34.6 20.9 19.6 17.4 17.1 22.7 18.9 43.6 44.1 37.4 21.0 24.1 13.1 25.6 26.2 20.0 17.4 86.0 39.0 21.2 34.6 17.4 20.5 130.7 13.5 18.6 59.3 28.1 24.3 21.5 12.1 21.8 16.3 18.7 30.9 15.2 30.3 25.3 14.9 11.9 12.8 27.2 18.4 37.0 22.1 40.1 36.5 31.7 12.9 12.7 23.3 26.4 34.2 23.9 39.9 3.4 22.6 26.2 36.2 38.7 34.5 21.5 30.4 28.3 36.2 29.2 27.3 19.0 22.7 12.8 50.9 23.5 30.3 42.4 18.0 32.6 18.9 13.2 108.0 111.3 39.7 15.8 5.1 11.3 14.3 23.9 0.4 0.2 23.0 51.2 30.2 14.4 60.9 32.0 19.7 17.7 37.1 28.8 43.0 19.0 11.4 22.3 0.9 33.0 15.3 45.0 66.1 6.8 29.7 0.2 26.5 21.6 14.5 11.2 1.0 4.4 1.6 4.7 0.7 0.2 12.2 7.3 1.2 0.9 18.7 0.1 3.3 6.2 3.7 6.6 30.6 35.2 16.8 42.7 43.6 44.1 25.6 26.2 34.6 12.1 30.9 27.2 20.0 19.2 48.0 47.0 23.0 19.8 56.7 15.7 32.5 164.8 15.7 16.5 21.1 28.6 18.3 14.7 294.0 34.3 16.7 46.2 11.7 16.3 4.0 32.8 27.4 22.2 84.9 45.8 125.0 18.5 15.7 31.0 23.4 74.0 24.1 74.5 16.4 37.8 53.8 95.9 112.3 27.3 12.2 37.8 29.2 3.9 17.4 42.8 40.9 38.4 17.7 59.3 3.1 61.3 80.5 24.2 37.6 23.7 13.8 32.7 56.9 32.5 11.4 403.4 6.6 39.4 32.3 38.8 18.2 21.7 20.2 99.9 6.9 35.0 24.5 14.9 ATXN7L3 DKFZp761G2113 ENSG00000087152 "Ataxin 7 like 3" Q14CW9 17 44191805-44200113 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064316 Supported Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 20: HeLa - Mitochondria" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "Plasma membrane" "HPA064316: AB_2685243" "unprognostic (2.37e-2)" "unprognostic (8.87e-3)" "unprognostic (1.10e-1)" "unprognostic (3.74e-2)" "unprognostic (3.75e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (4.03e-4)" "unprognostic (2.86e-3)" "unprognostic (6.74e-3)" "unprognostic (1.09e-1)" "unprognostic (1.50e-1)" "unprognostic (1.00e-1)" "prognostic unfavorable (2.87e-4)" "unprognostic (1.21e-3)" "unprognostic (9.05e-2)" "unprognostic (3.75e-2)" "unprognostic (1.40e-1)" 23.3 24.6 51.0 32.6 58.1 45.0 21.3 28.0 76.6 28.4 12.0 26.8 31.2 28.3 25.9 40.1 26.5 24.1 24.9 58.5 35.9 29.2 28.0 25.2 37.2 58.3 42.4 25.5 24.2 24.5 35.1 30.7 60.6 26.9 24.3 21.5 27.9 27.7 25.3 31.2 29.6 25.8 33.0 36.3 28.3 36.9 48.3 42.1 29.1 22.6 35.5 28.7 28.1 54.1 40.9 67.7 73.3 47.8 50.1 49.5 39.8 49.1 54.3 61.4 57.7 52.0 45.1 71.3 38.6 55.5 56.6 43.9 57.7 46.1 51.2 83.6 57.2 48.5 58.9 58.5 49.3 76.3 94.3 56.1 69.0 51.7 54.1 65.0 60.3 54.2 66.1 43.5 40.8 30.7 92.3 58.0 55.1 36.7 52.5 62.8 70.9 54.1 49.8 57.9 46.5 59.0 29.0 25.4 50.5 101.4 62.0 67.1 52.2 61.5 63.8 32.3 46.5 52.1 73.8 86.4 40.6 32.6 36.8 0.4 1.2 1.5 1.7 0.7 1.0 1.4 1.4 1.1 1.0 2.4 1.0 1.3 2.5 0.5 0.9 1.6 0.8 1.1 51.0 58.1 28.0 76.6 58.5 35.9 58.3 42.4 60.6 33.0 48.3 54.1 14.3 3.2 3.7 5.5 9.4 7.1 5.6 8.0 8.6 17.4 13.7 9.1 6.2 5.7 6.6 18.4 16.7 6.3 11.3 22.2 3.9 7.1 14.7 14.0 16.9 10.5 14.4 4.0 9.1 13.1 6.7 7.2 8.6 20.7 2.5 9.9 10.4 8.1 8.4 28.6 8.6 11.0 4.1 11.1 10.9 40.0 9.0 10.0 5.4 8.4 12.7 8.6 5.2 3.0 5.3 15.0 13.6 5.7 5.5 8.6 14.1 4.6 7.6 13.9 6.6 6.7 9.3 6.3 8.5 11.0 10.5 13.7 10.0 10.4 11.2 9.1 BARD1 ENSG00000138376 "BRCA1 associated RING domain 1" Q99728 2 214725646-214809683 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 68.6;Basal prostatic cells: 62.2;Suprabasal keratinocytes: 74.4;Urothelial cells: 67.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB034106, HPA035354, HPA044864" Enhanced Supported "Nucleoplasm,Nuclear speckles,Cytoplasmic bodies" No Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Nuclear speckles" "Cytoplasmic bodies" "CAB034106: AB_2061237, HPA035354: AB_2674585, HPA044864: AB_2679119" "unprognostic (4.85e-2)" "unprognostic (1.87e-2)" "unprognostic (1.74e-2)" "unprognostic (8.37e-3)" "unprognostic (2.57e-2)" "unprognostic (1.03e-2)" "unprognostic (6.25e-4)" "unprognostic (1.99e-1)" "unprognostic (2.16e-2)" "unprognostic (3.92e-3)" "unprognostic (2.80e-2)" "unprognostic (7.41e-2)" "unprognostic (1.94e-8)" "unprognostic (3.94e-2)" "unprognostic (2.28e-1)" "unprognostic (1.57e-1)" "unprognostic (1.08e-1)" 1.8 0.6 3.0 2.7 4.6 11.4 2.9 2.2 2.7 3.1 0.2 2.9 2.3 3.3 2.6 5.1 1.9 2.0 1.5 2.3 4.1 0.8 1.0 2.5 5.5 3.8 3.2 2.3 1.6 2.3 1.2 2.3 3.9 2.9 3.6 2.0 1.9 3.6 4.2 8.8 2.1 3.9 3.9 2.6 1.9 6.6 4.1 7.0 1.4 2.3 6.6 2.1 3.8 4.2 12.3 8.8 20.2 9.3 2.7 4.0 12.0 17.3 10.6 17.8 21.8 12.0 12.2 12.6 7.6 8.5 9.5 12.7 16.5 10.5 22.7 11.5 6.4 12.5 13.8 8.7 0.9 13.9 12.7 4.7 1.1 15.0 8.1 4.5 6.1 14.7 7.9 36.0 13.7 10.7 27.9 12.5 14.3 7.9 3.7 24.7 19.8 11.2 3.9 14.0 5.8 8.8 15.0 14.7 5.3 10.9 16.3 13.4 4.7 18.0 14.0 11.7 13.6 10.2 12.6 28.0 7.6 11.3 13.4 3.9 2.0 5.8 4.6 4.0 3.2 9.7 5.4 5.5 3.6 8.2 2.4 4.0 0.3 7.3 3.8 6.9 17.1 2.3 3.0 4.6 2.2 2.7 2.3 4.1 3.8 3.2 3.9 3.9 4.1 4.2 12.3 6.4 2.2 14.7 13.0 68.6 62.2 13.0 14.2 3.3 9.9 14.1 17.4 17.2 12.7 9.2 0.0 18.2 11.3 8.2 3.9 8.0 9.2 13.3 11.9 9.6 1.2 34.5 5.5 6.9 16.0 10.0 10.2 18.0 15.2 28.2 10.0 4.2 12.5 1.7 15.4 13.1 8.2 10.1 12.2 5.7 6.2 11.2 3.6 15.9 16.6 4.4 9.2 19.6 31.7 6.5 6.5 10.1 22.0 22.9 3.2 0.7 12.3 6.8 19.7 15.4 16.9 27.6 43.4 28.6 74.4 5.1 13.4 10.5 14.7 67.2 BAZ2A "KIAA0314, TIP5, WALp3" ENSG00000076108 "Bromodomain adjacent to zinc finger domain 2A" Q9UIF9 12 56595596-56636816 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005782, HPA063806" Enhanced "Nuclear speckles" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 34: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nuclear speckles" "HPA005782: AB_10601089, HPA063806: AB_2685128" "unprognostic (1.70e-1)" "unprognostic (1.75e-2)" "unprognostic (5.76e-2)" "unprognostic (1.73e-2)" "unprognostic (1.91e-1)" "unprognostic (2.26e-1)" "prognostic unfavorable (2.72e-4)" "unprognostic (3.72e-2)" "unprognostic (3.10e-1)" "unprognostic (6.45e-2)" "unprognostic (9.64e-2)" "unprognostic (3.00e-2)" "unprognostic (3.77e-2)" "unprognostic (1.73e-1)" "unprognostic (1.15e-1)" "unprognostic (2.25e-2)" "unprognostic (3.43e-1)" 29.1 23.9 10.3 30.8 13.3 65.9 27.2 22.9 18.7 29.3 19.1 27.0 25.5 25.4 22.9 30.9 24.9 20.9 21.1 10.3 20.0 19.8 21.7 35.9 33.4 17.2 13.0 36.3 30.8 33.4 27.7 35.4 14.6 23.3 26.6 48.8 25.7 21.0 28.2 29.9 31.1 23.1 5.5 35.3 26.2 47.4 19.0 50.6 27.3 32.0 30.6 24.8 30.6 19.8 50.3 45.6 61.9 52.5 35.3 35.4 66.5 32.6 44.2 46.9 34.1 56.2 59.3 69.2 49.2 38.6 44.3 41.5 70.6 46.3 40.6 48.1 37.1 80.8 35.5 28.8 38.5 47.1 60.2 31.0 43.8 40.2 55.7 50.8 46.3 28.4 87.7 94.1 26.3 30.7 40.2 30.9 54.9 32.7 34.6 33.9 45.0 48.3 32.6 48.8 41.0 33.8 54.8 57.0 30.0 66.0 65.6 41.7 65.2 24.3 49.1 30.0 23.0 46.0 48.4 65.1 22.5 33.4 34.6 12.1 7.6 5.6 4.8 6.2 4.2 6.8 3.8 3.7 3.0 6.0 3.1 2.7 28.6 17.2 15.5 11.7 3.6 3.0 10.3 13.3 22.9 18.7 10.3 20.0 17.2 13.0 14.6 5.5 19.0 19.8 47.6 67.3 61.3 29.4 74.7 50.9 43.2 35.3 60.3 70.5 43.3 26.7 26.4 30.0 36.9 25.8 137.6 48.0 62.8 71.6 7.9 32.0 66.8 29.4 33.7 50.1 44.8 53.4 29.3 28.7 37.2 35.6 34.1 41.7 43.6 34.8 53.9 32.5 24.3 32.0 27.4 39.6 26.4 62.1 65.6 73.7 60.6 38.5 39.2 40.3 80.1 24.4 116.4 25.6 33.2 34.8 39.4 57.6 78.0 65.1 44.7 12.6 34.4 67.3 85.5 44.9 44.0 134.1 131.2 59.5 61.8 95.6 58.0 41.6 34.8 67.6 BCAS2 "DAM1, Snt309, SPF27" ENSG00000116752 "BCAS2 pre-mRNA processing factor" O75934 1 114567557-114581629 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 613.4" "Low region specificity" "Detected in all" HPA067881 Supported Supported "Nuclear speckles,Centrosome" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" "Nuclear speckles, Centrosome" "HPA067881: AB_2685915" "unprognostic (6.93e-2)" "unprognostic (1.88e-2)" "unprognostic (8.58e-3)" "unprognostic (4.74e-2)" "unprognostic (2.49e-1)" "unprognostic (2.99e-3)" "prognostic unfavorable (8.23e-7)" "unprognostic (1.16e-1)" "unprognostic (8.51e-3)" "prognostic favorable (7.96e-4)" "unprognostic (1.57e-2)" "prognostic unfavorable (4.27e-4)" "prognostic favorable (6.49e-4)" "unprognostic (2.25e-3)" "unprognostic (1.03e-1)" "prognostic unfavorable (5.24e-4)" "unprognostic (1.87e-1)" 31.9 40.6 32.8 28.0 35.4 76.2 38.2 36.7 45.3 27.1 34.6 31.6 25.5 35.1 49.7 34.1 24.9 31.8 39.3 35.7 38.8 44.6 51.3 26.9 38.5 34.9 37.6 32.5 28.8 41.3 33.1 27.8 37.8 35.6 32.1 40.4 29.6 27.2 56.4 29.8 26.1 27.8 34.7 26.1 28.7 31.8 34.6 32.2 42.4 25.9 36.2 41.5 23.4 37.7 100.0 35.6 70.8 69.9 37.8 43.8 108.8 71.3 57.0 95.6 97.4 50.8 40.6 88.8 93.9 46.9 64.3 47.8 85.5 72.7 133.3 76.7 75.7 45.0 67.2 74.6 68.8 117.8 48.1 39.2 79.4 97.5 121.3 44.2 63.7 95.0 89.6 64.5 80.5 613.4 103.1 87.5 125.6 60.8 80.8 73.9 127.6 62.2 68.1 85.9 93.5 62.2 90.3 70.3 114.3 59.6 62.3 91.0 52.8 58.2 74.7 116.9 138.2 68.5 76.9 143.4 113.4 94.7 223.9 54.4 36.8 65.3 56.0 45.2 78.9 63.3 71.6 70.6 39.7 58.0 73.8 71.9 34.7 75.0 51.0 51.2 77.6 72.8 32.8 35.4 36.7 45.3 35.7 38.8 34.9 37.6 37.8 34.7 34.6 37.7 51.6 28.9 45.4 11.1 110.1 77.9 114.2 155.9 91.0 62.6 36.7 49.1 76.0 27.1 85.4 49.7 37.5 76.6 99.0 26.4 95.9 66.6 30.3 79.0 51.5 46.9 50.0 30.5 16.4 66.8 89.8 60.0 25.0 139.1 99.1 46.0 28.2 31.3 66.9 38.7 15.1 43.1 103.7 34.9 93.3 17.7 39.7 80.8 67.6 12.2 50.6 98.3 55.6 15.1 18.1 51.2 37.9 43.6 176.7 49.8 29.4 103.9 55.6 67.1 39.5 55.5 71.4 80.8 40.6 95.7 63.4 101.2 117.4 64.2 36.0 114.2 BCL2L2-PABPN1 ENSG00000258643 "BCL2L2-PABPN1 readthrough" Q92843 14 23306833-23326175 "Cancer-related genes, Predicted intracellular proteins, Transporters" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 10.1;Excitatory neurons: 10.9;Inhibitory neurons: 14.4;Oligodendrocyte precursor cells: 16.6;Oligodendrocytes: 13.7" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000637, HPA048740" Approved Uncertain "Nucleoplasm,Nuclear speckles" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nuclear speckles" "HPA000637: AB_1079553, HPA048740: " "unprognostic (1.32e-2)" "unprognostic (8.74e-2)" "unprognostic (1.21e-1)" "unprognostic (1.32e-3)" "unprognostic (9.82e-3)" "unprognostic (2.85e-2)" "unprognostic (1.05e-6)" "unprognostic (4.39e-2)" "unprognostic (1.67e-1)" "unprognostic (1.84e-3)" "unprognostic (7.61e-2)" "unprognostic (3.47e-2)" "unprognostic (1.72e-7)" "unprognostic (3.13e-2)" "unprognostic (8.77e-2)" "unprognostic (3.46e-3)" "unprognostic (4.95e-2)" 8.2 4.1 8.8 4.2 10.8 10.7 9.6 7.2 20.6 10.9 1.3 17.2 10.4 8.3 2.0 11.6 10.8 10.9 7.2 9.8 8.3 3.5 4.2 7.3 4.3 8.7 9.3 4.6 12.4 8.0 7.1 10.9 9.0 12.1 6.3 5.6 24.9 22.1 4.8 11.0 8.8 7.7 10.1 6.0 10.3 12.5 11.7 1.2 8.7 0.9 4.1 13.4 7.5 15.8 11.4 18.0 15.2 31.3 15.3 29.3 14.0 13.4 27.3 39.8 44.2 10.1 38.0 3.5 4.0 21.2 22.5 24.2 16.9 21.4 17.9 8.5 21.6 4.7 11.2 26.0 14.5 10.0 29.7 37.4 29.7 17.6 6.1 27.3 14.7 0.2 8.2 8.2 19.3 18.1 0.4 7.5 17.3 10.3 18.2 7.9 4.0 5.9 10.3 10.1 16.0 10.0 9.8 22.6 15.2 10.8 8.7 8.2 15.4 18.7 8.4 17.1 12.8 4.9 6.6 1.1 25.2 10.5 19.4 0.8 2.5 0.1 0.1 1.2 0.0 0.5 0.0 0.0 0.8 1.0 0.1 0.0 0.5 1.6 1.4 0.4 0.0 0.6 8.8 10.8 7.2 20.6 9.8 8.3 8.7 9.3 9.0 10.1 11.7 15.8 0.0 3.2 3.9 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.0 10.9 0.0 0.0 0.7 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 14.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 2.8 0.0 0.0 0.0 16.6 13.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 BCLAF1 "BTF, KIAA0164" ENSG00000029363 "BCL2 associated transcription factor 1" Q9NYF8 6 136256627-136289851 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 135.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006484, HPA006669, HPA027770" Enhanced Enhanced "Nuclear speckles" NA NA 21000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "HPA006484: AB_2667600, HPA006669: AB_1078302, HPA027770: AB_1845484" "prognostic unfavorable (1.64e-4)" "unprognostic (1.60e-1)" "prognostic favorable (3.44e-4)" "unprognostic (1.45e-1)" "unprognostic (9.46e-3)" "unprognostic (2.29e-1)" "unprognostic (2.13e-3)" "unprognostic (1.63e-1)" "unprognostic (5.07e-2)" "unprognostic (1.14e-1)" "unprognostic (2.69e-1)" "unprognostic (1.40e-1)" "unprognostic (7.20e-2)" "unprognostic (1.08e-1)" "unprognostic (1.56e-1)" "unprognostic (7.93e-2)" "unprognostic (4.19e-3)" 24.4 22.3 14.3 26.9 17.3 135.0 32.9 23.6 18.6 21.4 19.7 29.5 18.8 23.2 24.0 24.3 21.3 14.8 16.7 15.9 19.2 21.5 27.4 24.6 28.2 11.1 12.9 24.4 25.5 33.4 18.0 21.3 12.0 21.2 28.4 34.8 21.2 20.5 27.5 21.8 21.1 28.3 14.7 24.8 27.9 21.3 16.7 35.2 30.4 24.3 32.9 23.0 19.3 19.3 82.4 70.0 162.5 136.2 50.4 42.6 82.3 153.0 94.4 100.6 106.5 100.4 54.4 172.7 92.8 117.9 112.8 78.0 183.5 101.1 125.5 95.1 114.2 213.7 96.0 110.3 58.6 362.6 131.0 58.3 49.2 142.8 88.6 37.2 90.9 77.6 193.6 82.3 107.0 97.4 145.3 40.2 120.2 55.2 72.0 130.3 203.2 76.4 76.3 155.0 137.2 94.5 150.0 71.3 60.4 60.6 66.9 71.5 125.7 79.2 116.7 95.9 151.2 69.5 134.8 227.9 47.2 113.3 94.2 32.6 27.1 42.1 32.4 33.2 32.7 36.6 29.9 28.1 42.3 32.9 37.7 34.5 57.9 49.5 35.3 24.7 25.5 24.5 14.3 17.3 23.6 18.6 15.9 19.2 11.1 12.9 12.0 14.7 16.7 19.3 165.3 205.1 178.7 68.9 174.3 68.2 118.9 99.5 104.2 129.7 86.9 71.5 88.4 65.8 131.6 57.0 210.6 111.9 173.3 86.3 33.2 96.8 12.6 157.2 173.5 117.5 118.9 134.6 80.5 65.2 99.4 138.0 128.0 169.8 156.4 130.5 74.3 60.0 74.0 102.6 82.6 106.0 93.6 92.5 88.9 13.8 122.1 121.8 69.4 56.2 136.9 91.6 118.4 63.3 93.4 77.5 81.4 109.4 197.8 128.6 83.3 42.9 147.1 139.9 111.7 259.8 130.7 102.2 129.7 121.4 71.2 128.3 174.8 154.8 101.6 123.8 BDNF ENSG00000176697 "Brain derived neurotrophic factor" P23560 11 27654893-27722058 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 38.5;Bipolar cells: 13.8;Cardiomyocytes: 9.1;Excitatory neurons: 22.3;Smooth muscle cells: 25.8;Theca cells: 9.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 36.6;BJ hTERT+ SV40 Large T+: 28.0;BJ hTERT+ SV40 Large T+ RasG12V: 20.9;HBF TERT88: 26.5;U-138 MG: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB009564, HPA031440, HPA056104" Enhanced Supported "Nuclear speckles,Mitochondria" "Secreted to blood" NA Yes 16000000 24000 "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles, Mitochondria" "CAB009564: AB_2064213, HPA031440: AB_2673883, HPA056104: AB_2683038" "unprognostic (1.25e-2)" "unprognostic (2.84e-1)" "unprognostic (4.35e-2)" "unprognostic (2.54e-2)" "unprognostic (1.01e-2)" "unprognostic (6.82e-2)" "unprognostic (2.39e-2)" "unprognostic (2.21e-1)" "unprognostic (3.20e-1)" "unprognostic (1.78e-1)" "unprognostic (1.22e-2)" "unprognostic (2.65e-1)" "unprognostic (3.22e-2)" "unprognostic (3.88e-2)" "unprognostic (5.88e-2)" "unprognostic (1.40e-1)" "unprognostic (2.84e-3)" 0.4 0.5 1.9 0.2 2.4 0.2 0.2 3.3 5.3 0.6 0.1 0.4 0.3 0.2 3.3 0.6 0.1 0.7 3.6 8.2 1.9 0.6 0.1 2.0 0.1 3.3 2.1 0.5 0.4 0.0 1.2 1.6 2.5 2.0 0.1 0.7 0.3 1.8 0.4 0.9 0.1 0.1 0.4 0.1 0.3 0.6 1.6 0.3 1.0 0.0 0.1 2.1 0.6 0.8 2.9 12.2 0.3 0.0 3.7 2.2 0.0 36.6 7.9 28.0 20.9 0.1 4.0 0.0 3.7 11.8 0.5 1.4 0.1 0.2 26.5 0.2 0.1 0.0 3.5 0.0 17.4 0.2 0.2 9.2 4.2 6.8 3.7 18.1 1.3 0.1 0.0 0.1 4.8 0.0 0.0 0.0 4.0 0.1 2.9 0.0 2.0 0.0 4.5 0.0 0.2 1.1 7.8 0.1 0.1 1.7 0.2 0.0 11.0 37.6 6.9 14.4 9.2 0.5 0.1 0.0 14.1 1.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.4 3.3 5.3 8.2 1.9 3.3 2.1 2.5 0.4 1.6 0.8 0.2 38.5 0.5 1.6 0.0 0.6 0.4 0.5 1.8 13.8 0.5 0.9 9.1 0.0 0.4 1.8 4.2 0.4 0.0 0.1 0.0 0.8 1.8 0.3 0.3 0.2 0.0 0.0 22.3 0.0 0.5 6.1 0.0 0.1 1.3 1.9 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.4 1.5 0.3 0.9 1.8 0.0 0.0 0.2 0.0 2.0 2.2 0.2 0.0 0.0 0.0 0.8 0.0 1.5 0.1 1.8 0.0 1.8 25.8 3.7 0.8 2.3 0.0 0.7 0.0 9.3 0.1 0.1 BEND5 "C1orf165, FLJ11588" ENSG00000162373 "BEN domain containing 5" Q7L4P6 1 48727519-48776969 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 54.8;Proximal tubular cells: 30.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 6.5;naive B-cell: 8.0" "Lineage enriched" "Detected in many" 5 "B-cells: 8.0" "Cell line enhanced" "Detected in some" "AF22: 3.4;HDLM-2: 11.7;JURKAT: 4.5;MOLT-4: 4.8;REH: 6.5;SH-SY5Y: 2.9" "Low region specificity" "Detected in many" "HPA054347, HPA058007" Uncertain Approved "Nuclear speckles,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Nuclear speckles" Cytosol "HPA054347: AB_2682456, HPA058007: AB_2683577" "prognostic favorable (2.50e-5)" "unprognostic (1.36e-2)" "unprognostic (7.19e-3)" "unprognostic (1.16e-1)" "unprognostic (1.11e-1)" "unprognostic (1.65e-2)" "unprognostic (4.42e-2)" "prognostic favorable (1.29e-4)" "unprognostic (1.41e-1)" "unprognostic (6.02e-2)" "prognostic favorable (1.29e-4)" "unprognostic (1.32e-2)" "unprognostic (4.28e-2)" "unprognostic (2.37e-3)" "unprognostic (3.35e-2)" "unprognostic (9.68e-2)" "prognostic favorable (8.30e-6)" 1.7 1.9 5.1 0.7 5.1 1.0 1.8 4.1 7.4 2.8 4.1 3.4 0.4 2.0 1.5 0.6 2.5 2.0 1.6 5.1 4.3 3.4 0.1 0.9 2.1 6.3 5.0 4.4 1.7 1.8 3.4 0.3 6.4 1.5 0.4 3.7 1.0 1.2 2.6 0.8 1.6 0.7 4.1 2.7 1.7 1.0 4.8 4.8 1.8 1.7 1.4 2.2 1.7 5.3 0.0 0.0 3.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.1 0.0 4.8 0.2 2.6 0.0 0.0 6.5 1.1 0.0 0.0 1.2 1.1 2.9 0.0 0.0 0.2 1.2 0.0 0.3 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.2 1.7 8.0 1.6 1.0 0.2 1.2 0.0 1.7 0.0 0.4 5.1 5.1 4.1 7.4 5.1 4.3 6.3 5.0 6.4 4.1 4.8 5.3 8.7 6.4 3.1 0.0 17.2 1.9 4.6 4.6 1.8 13.3 4.0 16.9 8.6 8.6 6.1 5.5 16.7 0.3 0.6 0.5 54.8 6.4 8.9 2.7 1.9 6.9 12.1 0.8 0.0 1.8 0.5 8.4 2.6 1.3 1.3 10.2 4.6 0.2 0.3 8.4 0.0 0.8 2.0 0.6 4.4 7.1 13.1 1.5 3.6 0.0 0.5 22.7 0.0 0.0 0.0 2.6 4.5 21.4 7.6 1.1 0.2 30.2 6.4 17.8 6.6 6.8 5.6 3.7 9.1 0.3 2.3 0.1 2.8 11.4 1.6 1.9 BHLHE22 "Beta3, BHLHB5, CAGL85, TNRC20" ENSG00000180828 "Basic helix-loop-helix family member e22" Q8NFJ8 8 64580365-64583627 "Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 23.2" "Cell type enriched" "Detected in some" 14 "Bipolar cells: 64.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 23 "THP-1: 78.4" "Group enriched" "Detected in all" 5 "amygdala: 30.7;cerebellum: 30.7;cerebral cortex: 22.7;hippocampal formation: 46.3;white matter: 13.1" "HPA064128, HPA064872, HPA067500" Enhanced Approved "Nucleoplasm,Nuclear speckles,Centrosome,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Nuclear speckles" "Centrosome, Cytosol" "HPA064128: AB_2685195, HPA064872: AB_2685377, HPA067500: AB_2685855" "unprognostic (9.17e-2)" "unprognostic (1.11e-2)" "unprognostic (5.44e-2)" "unprognostic (2.28e-5)" "unprognostic (7.22e-3)" "unprognostic (6.47e-4)" "unprognostic (2.41e-1)" "unprognostic (1.08e-1)" "unprognostic (1.30e-1)" "unprognostic (6.58e-2)" "unprognostic (1.52e-1)" "unprognostic (3.71e-2)" "unprognostic (2.86e-7)" "unprognostic (3.20e-2)" "unprognostic (2.29e-1)" "unprognostic (6.72e-3)" "unprognostic (1.86e-1)" 2.0 0.5 8.9 1.4 6.6 0.0 1.5 12.1 22.4 2.3 0.4 1.3 0.4 0.3 0.1 0.9 0.8 0.4 0.3 23.2 1.5 0.2 0.5 2.0 0.7 5.5 1.5 0.2 0.7 0.1 1.4 0.0 2.6 0.4 0.5 4.4 0.5 2.3 0.1 0.8 1.4 0.4 1.4 1.4 0.5 0.2 1.1 0.3 0.7 0.0 0.6 1.2 2.9 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 78.4 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 6.6 12.1 22.4 23.2 1.5 5.5 1.5 2.6 1.4 1.1 1.8 0.3 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 64.7 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 1.2 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 3.1 0.0 3.4 0.2 0.0 0.0 0.6 1.5 0.0 1.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 3.0 0.0 0.2 2.9 0.0 0.4 0.1 1.6 0.0 0.1 0.0 0.0 0.0 BMP2K "BIKe, DKFZp434K0614" ENSG00000138756 "BMP2 inducible kinase" Q9NSY1 4 78776342-78916365 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 242.9;granulocytes: 129.2;Hofbauer cells: 140.4;Microglial cells: 351.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "fHDF/TERT166: 50.1;HEL: 73.6;HMC-1: 80.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026436, HPA026451, HPA026501" Approved Supported "Nuclear speckles" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Nuclear speckles" "HPA026436: AB_10600102, HPA026451: AB_10600228, HPA026501: AB_10601341" "unprognostic (7.96e-2)" "unprognostic (3.68e-1)" "prognostic favorable (1.74e-4)" "unprognostic (9.08e-2)" "unprognostic (1.97e-1)" "unprognostic (9.73e-3)" "unprognostic (1.51e-2)" "unprognostic (1.47e-1)" "unprognostic (2.98e-1)" "unprognostic (7.60e-2)" "unprognostic (1.39e-1)" "unprognostic (9.60e-2)" "unprognostic (9.90e-2)" "unprognostic (9.45e-2)" "unprognostic (1.59e-1)" "unprognostic (1.55e-2)" "unprognostic (3.18e-2)" 6.0 4.2 8.5 13.5 8.2 11.9 7.4 7.3 7.2 6.5 3.8 9.5 5.6 4.4 5.4 7.4 6.0 7.4 8.0 7.2 18.6 4.9 6.7 7.7 16.5 12.1 11.2 3.1 3.5 4.3 0.6 9.2 13.5 3.3 11.9 6.5 3.5 3.5 2.2 9.9 6.9 6.6 10.9 12.2 4.7 10.2 9.8 10.9 7.7 4.5 16.3 7.1 1.4 16.5 11.4 3.2 6.0 7.5 12.0 11.1 4.8 10.8 14.4 10.3 13.7 6.4 6.4 13.2 5.6 50.1 9.9 2.9 6.7 8.5 19.4 3.5 2.3 73.6 5.0 3.5 13.2 15.9 80.6 15.9 11.0 16.4 15.6 7.3 14.4 10.0 19.8 36.5 12.1 2.4 9.5 7.4 2.9 8.8 2.1 13.5 10.3 3.7 13.3 5.2 8.4 5.2 14.2 7.8 10.4 7.9 2.7 10.0 14.7 10.6 4.2 18.4 11.9 7.7 3.2 4.8 9.9 21.4 7.7 0.1 0.5 0.3 0.0 0.2 0.0 0.6 0.0 0.0 0.4 0.6 0.1 0.0 0.9 0.1 0.8 0.3 0.0 0.1 8.5 8.2 7.3 7.2 7.2 18.6 12.1 11.2 13.5 10.9 9.8 16.5 10.7 28.9 16.2 242.9 31.5 25.0 4.3 5.4 10.2 10.9 27.4 15.2 6.5 2.8 7.7 7.3 4.2 5.0 6.1 24.6 0.0 7.5 15.9 18.6 12.7 17.6 6.7 105.4 53.2 8.8 14.2 13.7 6.6 25.0 129.2 32.1 22.1 19.7 140.4 10.1 59.0 48.2 6.1 65.9 68.2 11.1 8.1 65.4 28.4 351.3 34.6 37.0 1.0 49.3 59.1 14.6 43.0 6.8 7.6 6.3 19.9 18.0 12.3 8.4 6.6 22.3 11.7 26.1 11.2 17.1 31.4 3.4 7.6 5.4 24.0 3.2 BNIP3L "BNIP3a, Nix" ENSG00000104765 "BCL2 interacting protein 3 like" O60238 8 26383054-26505636 "Cancer-related genes, Predicted membrane proteins, Transporters" "Apoptosis, Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 913.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015652, CAB025371" Enhanced Supported "Nuclear speckles,Mitochondria" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 6: Erythroid cells - Oxygen transport" Mitochondria "Nuclear speckles" "CAB025371: , HPA015652: AB_1845406" "unprognostic (1.02e-1)" "unprognostic (2.90e-1)" "unprognostic (2.00e-1)" "unprognostic (8.36e-2)" "unprognostic (6.24e-2)" "unprognostic (1.63e-1)" "unprognostic (1.64e-3)" "unprognostic (1.46e-2)" "unprognostic (5.04e-2)" "unprognostic (2.02e-1)" "unprognostic (2.06e-2)" "unprognostic (2.97e-2)" "prognostic unfavorable (5.92e-5)" "unprognostic (8.72e-3)" "unprognostic (5.16e-2)" "prognostic unfavorable (3.95e-4)" "unprognostic (7.59e-3)" 130.6 53.4 42.7 37.2 60.4 192.6 77.9 55.6 62.0 63.9 38.9 39.6 22.2 52.8 66.3 48.3 50.5 54.7 63.2 50.0 49.6 79.4 45.4 62.9 39.4 60.7 54.0 119.7 20.1 55.1 25.4 104.5 58.4 44.4 28.2 146.5 44.1 64.4 38.9 71.5 28.4 51.3 46.6 40.7 28.9 68.6 48.8 39.9 41.9 31.7 52.1 48.9 49.5 80.8 90.6 33.8 79.1 53.9 214.5 134.0 66.8 89.0 259.9 81.9 179.6 15.3 42.7 27.7 82.5 169.0 113.4 44.8 39.6 114.5 270.0 17.8 21.8 114.9 32.0 26.9 119.3 10.3 191.1 162.5 89.2 92.9 55.3 269.2 106.2 66.9 52.6 65.0 173.7 39.1 72.7 38.5 26.2 56.7 36.6 38.4 99.9 55.6 85.3 58.3 83.9 74.4 43.2 8.8 70.0 85.9 43.7 21.7 140.4 152.2 64.6 96.2 20.5 93.2 46.0 36.8 232.6 20.6 35.1 334.9 298.3 182.9 39.5 154.8 34.9 68.4 58.4 43.3 166.9 78.0 89.3 65.5 369.0 47.6 104.1 38.0 86.1 239.3 42.7 60.4 55.6 62.0 50.0 49.6 60.7 54.0 58.4 46.6 48.8 80.8 118.3 86.6 157.4 28.7 72.2 98.8 56.0 231.7 82.6 142.5 90.6 85.3 34.0 50.1 126.4 103.0 33.3 33.2 55.6 32.7 49.0 115.4 194.1 173.5 140.8 101.2 120.6 913.9 50.6 39.1 166.5 179.9 38.7 341.2 120.9 96.5 167.0 32.2 132.1 82.4 39.4 46.8 118.0 221.3 300.4 206.7 320.3 233.6 106.7 30.0 165.0 406.4 32.0 29.1 75.8 154.1 39.8 347.5 64.6 83.6 44.0 306.4 107.6 64.0 144.7 59.1 183.9 154.4 110.7 65.4 126.6 162.5 67.0 117.6 27.6 79.3 BORCS7 "C10orf32, FLJ40752" ENSG00000166275 "BLOC-1 related complex subunit 7" Q96B45 10 102854259-102864961 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 201.5;Proximal tubular cells: 208.5;Theca cells: 209.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA037648 Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 1: Thyroid gland - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" "Nuclear speckles" Cytosol "HPA037648: AB_10673634" "unprognostic (2.16e-1)" "unprognostic (1.66e-1)" "unprognostic (2.53e-1)" "unprognostic (1.01e-2)" "unprognostic (2.05e-1)" "unprognostic (1.32e-1)" "unprognostic (1.09e-3)" "unprognostic (3.55e-2)" "unprognostic (1.35e-2)" "unprognostic (7.46e-3)" "unprognostic (3.16e-2)" "unprognostic (1.77e-1)" "prognostic favorable (9.08e-8)" "unprognostic (9.85e-2)" "unprognostic (1.77e-1)" "unprognostic (1.06e-1)" "unprognostic (1.67e-3)" 25.4 58.5 20.5 12.8 20.9 23.4 29.8 20.3 25.1 21.3 22.3 19.7 23.2 21.8 23.7 13.4 29.7 22.4 22.3 21.5 23.1 39.8 67.0 23.8 15.1 21.2 21.7 21.8 17.5 53.3 23.7 21.7 21.3 27.2 15.2 20.2 16.9 17.4 28.6 13.9 19.5 16.7 22.5 24.4 20.9 20.2 22.7 14.6 55.3 25.9 12.3 17.4 16.0 23.0 14.9 19.8 23.4 20.7 25.6 35.1 19.5 21.6 44.1 16.3 15.5 13.3 16.6 9.4 11.1 34.6 17.1 12.2 7.9 11.1 12.0 12.1 16.7 21.7 12.5 27.7 29.5 39.4 35.9 44.1 29.8 11.0 17.4 34.0 28.9 13.2 13.0 9.7 26.4 10.9 11.0 16.2 7.9 20.3 18.4 19.8 31.4 13.8 13.6 16.1 6.6 25.5 8.0 14.2 34.7 10.4 27.0 22.2 21.6 13.7 14.6 14.1 15.3 24.9 40.8 11.1 29.0 22.7 5.0 31.3 30.1 22.9 17.3 35.0 19.4 26.5 17.9 18.0 22.1 23.2 19.8 18.4 9.6 27.7 32.9 47.1 19.7 15.1 20.5 20.9 20.3 25.1 21.5 23.1 21.2 21.7 21.3 22.5 22.7 23.0 85.2 54.5 79.6 0.0 49.1 0.0 61.0 0.0 45.5 50.9 94.5 62.9 0.0 48.6 32.2 42.3 39.6 89.6 57.4 18.0 201.5 35.3 21.1 61.1 38.8 67.3 34.0 18.3 0.0 33.3 39.2 60.4 39.8 31.9 34.1 44.2 68.2 74.9 51.7 63.9 0.0 33.4 0.0 49.8 0.0 22.8 42.3 54.1 0.0 0.0 52.1 109.8 53.5 0.0 0.0 28.5 48.5 62.1 28.6 53.8 70.1 208.5 43.7 50.6 39.5 53.3 44.0 80.1 52.4 44.7 0.0 121.5 39.8 209.5 41.0 54.5 BPNT1 ENSG00000162813 "3'(2'), 5'-bisphosphate nucleotidase 1" O95861 1 220057482-220090462 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 55.5;Proximal enterocytes: 56.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 183.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048461 Approved Approved "Nuclear speckles" NA NA 420000 "Cluster 44: Non-specific - Transcription" "Cluster 9: Intestine - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 45: Enterocytes - Digestion" "Nuclear speckles" "HPA048461: AB_2680404" "unprognostic (6.42e-2)" "unprognostic (4.69e-2)" "unprognostic (2.78e-2)" "unprognostic (1.02e-1)" "unprognostic (5.19e-3)" "unprognostic (7.65e-2)" "unprognostic (2.07e-2)" "unprognostic (3.00e-1)" "unprognostic (2.44e-1)" "unprognostic (1.66e-1)" "unprognostic (6.69e-2)" "unprognostic (2.87e-1)" "prognostic favorable (6.38e-4)" "unprognostic (1.82e-2)" "unprognostic (6.58e-2)" "unprognostic (2.91e-1)" "unprognostic (1.35e-1)" 16.2 20.8 6.5 18.2 7.8 4.6 20.3 7.5 9.1 18.1 7.3 37.7 43.9 13.9 13.0 14.7 17.6 21.2 17.7 7.3 6.8 31.5 25.0 17.6 34.2 7.6 6.8 17.9 7.7 21.5 10.9 13.2 7.1 13.8 32.2 15.5 17.3 11.9 9.3 10.3 45.7 18.3 7.5 14.6 19.7 14.8 6.7 17.7 20.8 11.3 44.3 15.8 9.9 10.0 37.5 30.3 22.1 17.5 40.6 33.3 35.4 48.0 25.0 42.9 38.3 40.1 70.7 183.9 64.8 33.2 19.1 26.1 45.8 42.3 34.5 68.8 51.2 33.3 34.6 48.3 23.8 90.4 29.9 31.8 20.7 61.0 25.3 28.0 35.9 54.1 62.3 18.4 43.4 21.2 51.9 24.3 18.9 32.0 37.1 36.5 62.9 54.0 55.5 49.2 40.2 33.6 60.1 71.5 43.0 22.1 56.5 31.7 54.2 25.4 19.5 36.7 60.8 31.3 81.6 85.0 22.0 33.6 56.8 20.6 9.2 6.1 12.3 10.0 9.4 20.8 12.8 12.7 10.9 16.5 15.0 11.2 1.1 14.0 9.9 13.3 14.6 9.7 6.5 7.8 7.5 9.1 7.3 6.8 7.6 6.8 7.1 7.5 6.7 10.0 9.3 28.9 23.9 3.6 12.7 3.3 12.5 22.0 3.4 13.7 9.1 6.2 10.5 11.5 23.4 14.7 10.4 13.1 11.6 55.5 13.7 18.7 2.5 10.3 7.7 7.7 19.2 5.5 8.4 15.6 14.1 7.8 7.7 9.7 3.8 12.1 7.9 12.6 9.8 6.7 10.8 14.5 32.6 7.5 3.6 3.1 9.6 7.2 10.6 1.9 8.0 10.8 15.5 10.1 13.0 18.9 28.5 13.5 10.3 6.3 56.9 29.5 14.5 12.0 13.1 5.6 8.7 15.5 11.8 8.2 5.1 25.2 9.6 25.0 17.2 12.7 BRD1 "BRL, BRPF2" ENSG00000100425 "Bromodomain containing 1" O95696 22 49773283-49827512 "Predicted intracellular proteins" "Erythrocyte maturation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 76.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000807, HPA001063" Enhanced Supported "Nuclear speckles" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 14: REH - Unknown function" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles" "HPA000807: AB_1078298, HPA001063: AB_1078297" "unprognostic (1.96e-1)" "unprognostic (2.99e-2)" "unprognostic (1.07e-1)" "unprognostic (5.11e-3)" "unprognostic (1.07e-1)" "unprognostic (2.47e-2)" "unprognostic (2.18e-2)" "unprognostic (9.98e-2)" "unprognostic (2.73e-2)" "unprognostic (3.28e-2)" "unprognostic (2.02e-3)" "unprognostic (1.64e-3)" "unprognostic (5.87e-2)" "unprognostic (7.50e-2)" "unprognostic (1.06e-1)" "unprognostic (1.26e-1)" "unprognostic (3.95e-3)" 11.4 7.3 3.1 8.1 3.0 15.0 10.8 12.0 5.0 12.5 3.6 14.7 11.7 15.8 2.8 12.8 13.7 7.7 7.5 3.4 3.2 5.4 6.9 10.0 9.4 3.2 2.8 16.0 13.2 8.5 11.2 8.3 2.9 8.7 5.8 6.1 12.1 8.0 16.7 23.2 12.0 6.7 1.5 12.0 11.5 30.7 3.2 14.0 10.2 8.9 7.6 11.8 12.3 4.5 12.7 12.7 22.8 12.8 9.2 8.2 19.3 13.7 9.3 14.2 11.1 19.3 8.3 13.3 7.9 11.4 5.2 17.9 14.7 9.8 6.1 13.4 26.6 13.2 20.3 11.8 17.8 30.5 18.2 12.2 15.1 8.3 10.5 10.3 10.4 15.9 15.3 14.3 7.3 20.8 23.0 15.9 15.7 9.4 10.1 33.6 19.9 13.9 5.5 18.2 14.6 25.8 17.6 22.7 18.4 10.5 10.6 24.9 12.9 13.1 14.1 9.9 12.7 16.8 4.3 18.9 9.3 10.7 11.8 0.3 0.6 0.7 0.5 0.2 1.0 0.4 0.8 1.0 0.4 0.7 0.8 1.0 0.6 0.8 2.9 0.9 0.3 0.5 3.1 3.0 12.0 5.0 3.4 3.2 3.2 2.8 2.9 1.5 3.2 4.5 25.9 22.4 27.6 16.3 13.8 15.8 5.7 7.1 8.6 26.6 14.0 14.7 8.4 5.7 12.7 3.7 29.2 6.7 76.8 13.3 0.0 6.7 7.5 32.4 37.1 13.9 16.2 8.2 25.3 9.3 6.6 17.2 14.8 47.7 10.1 28.3 14.3 12.3 6.7 33.7 22.2 13.9 4.1 13.3 14.0 6.7 11.8 15.4 12.4 16.9 11.2 13.8 7.2 19.1 21.9 9.5 8.7 13.9 43.1 9.1 10.6 3.2 11.3 36.1 0.0 25.4 20.1 42.6 19.7 10.7 18.5 10.1 40.6 26.4 11.3 9.0 BRD2 "BRD2-IT1, D6S113E, FSRG1, KIAA9001, NAT, RING3" ENSG00000204256 "Bromodomain containing 2" P25440 6 32968594-32981505 "Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042816 Approved Enhanced "Nuclear speckles" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" "Nuclear speckles" "HPA042816: AB_10794766" "unprognostic (2.13e-1)" "unprognostic (2.43e-1)" "unprognostic (1.10e-1)" "unprognostic (4.60e-2)" "unprognostic (1.45e-1)" "unprognostic (9.89e-2)" "unprognostic (5.03e-2)" "unprognostic (2.54e-1)" "unprognostic (6.85e-3)" "unprognostic (1.39e-2)" "unprognostic (1.95e-2)" "unprognostic (3.42e-2)" "unprognostic (1.38e-1)" "unprognostic (2.98e-2)" "unprognostic (1.49e-1)" "unprognostic (1.20e-2)" "unprognostic (1.44e-2)" 64.2 61.8 0.8 22.1 2.1 66.5 62.4 4.7 3.8 67.7 0.2 62.1 19.8 71.3 1.8 67.9 66.6 17.4 51.7 3.0 2.8 68.3 61.9 65.3 22.1 1.5 2.4 81.7 80.4 26.3 71.4 19.4 2.1 60.8 11.6 10.1 66.1 18.2 71.4 69.5 60.8 11.7 1.4 71.2 66.0 82.9 2.3 26.9 77.0 10.4 21.2 61.6 65.0 4.0 45.7 19.5 41.6 41.8 31.8 28.5 38.3 44.6 44.4 48.5 35.8 22.7 22.5 37.3 44.6 37.2 32.4 28.1 39.3 33.2 27.7 49.5 147.7 41.2 18.3 14.6 23.5 60.6 39.2 29.2 28.7 38.2 44.9 27.6 21.3 35.2 44.4 76.0 21.7 12.1 77.0 8.5 24.0 28.9 20.4 76.2 18.7 53.8 13.8 26.6 85.6 28.9 54.5 63.7 52.7 27.8 37.4 39.0 27.5 58.6 32.0 21.5 50.0 61.1 69.5 77.9 23.1 19.7 47.8 9.6 7.6 11.6 14.5 8.8 13.0 9.2 9.4 9.9 10.6 8.7 6.6 10.4 9.7 10.3 9.5 8.5 13.3 11.7 0.8 2.1 4.7 3.8 3.0 2.8 1.5 2.4 2.1 1.4 2.3 4.0 325.8 76.9 121.5 38.2 327.1 212.1 232.7 70.0 478.1 78.6 295.5 383.9 171.7 94.4 80.1 60.7 104.3 91.7 395.7 210.7 21.5 69.2 302.4 201.9 149.3 191.2 259.1 97.6 16.1 91.4 145.0 224.2 249.8 256.6 115.2 103.1 113.2 85.3 79.9 55.5 19.9 247.5 77.3 92.6 209.2 177.9 86.9 194.5 124.5 26.2 94.7 62.8 107.1 15.1 22.1 81.2 137.3 77.1 313.0 211.5 133.7 39.5 84.4 65.1 39.5 240.0 251.3 88.4 137.9 365.0 226.9 205.1 356.7 71.2 179.5 248.4 BRK1 "C3orf10, HSPC300, MDS027" ENSG00000254999 "BRICK1 subunit of SCAR/WAVE actin nucleating complex" Q8WUW1 3 10115675-10127190 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 2544.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060391 Approved "Nuclear speckles,Cell Junctions" NA NA 170000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Nuclear speckles" "Cell Junctions" "HPA060391: AB_2684272" "unprognostic (4.99e-2)" "unprognostic (3.48e-2)" "unprognostic (2.64e-1)" "unprognostic (3.83e-2)" "unprognostic (2.91e-1)" "unprognostic (9.60e-2)" "prognostic unfavorable (5.76e-5)" "unprognostic (2.49e-2)" "unprognostic (2.89e-1)" "unprognostic (1.09e-1)" "unprognostic (1.89e-1)" "unprognostic (1.37e-1)" "unprognostic (7.14e-3)" "unprognostic (1.12e-1)" "unprognostic (9.40e-2)" "unprognostic (4.35e-2)" "unprognostic (7.75e-3)" 165.2 120.7 167.4 109.9 169.3 163.5 161.3 163.9 201.1 157.7 166.2 186.4 101.2 150.9 171.6 175.7 152.6 118.1 154.3 173.0 174.0 176.6 154.4 135.2 157.3 165.7 165.3 152.5 116.7 154.5 111.5 109.3 165.5 138.0 133.2 62.1 137.8 130.3 185.7 153.8 123.4 155.3 168.9 131.2 150.9 142.1 172.4 151.7 134.0 167.3 180.3 174.1 147.6 169.0 179.1 210.4 218.0 114.1 358.2 389.0 516.5 259.0 258.1 238.9 235.6 145.5 203.9 205.1 120.5 301.0 208.2 91.0 159.7 263.9 260.5 227.3 220.8 282.7 233.5 219.9 203.4 272.1 204.2 256.8 250.4 267.9 193.0 312.2 339.2 168.9 187.3 231.9 366.4 393.0 177.1 216.7 252.1 251.9 263.6 168.8 224.5 224.2 315.9 292.5 84.6 146.8 208.6 179.3 217.2 216.0 291.8 233.8 307.9 237.9 182.2 281.4 234.8 131.9 385.1 460.6 343.9 368.5 200.4 303.2 334.5 357.1 238.7 337.0 213.8 304.7 228.6 226.9 380.0 307.9 205.9 223.5 337.5 228.7 345.8 404.8 287.9 469.9 167.4 169.3 163.9 201.1 173.0 174.0 165.7 165.3 165.5 168.9 172.4 169.0 224.7 64.1 79.3 16.6 198.4 263.8 307.2 560.2 137.7 41.6 332.8 352.2 125.5 233.1 291.4 204.1 20.9 254.2 220.3 149.0 493.1 375.7 1034.0 145.6 152.2 273.7 298.7 191.2 33.5 361.6 282.9 223.2 119.3 127.3 173.3 152.3 272.4 255.0 442.7 47.1 20.7 211.3 307.2 373.9 380.3 2544.4 247.3 295.5 354.0 28.1 556.8 208.4 375.9 13.6 21.7 479.4 202.9 253.9 130.2 338.3 274.7 887.5 204.6 38.7 236.7 158.7 254.6 212.0 160.1 264.4 315.4 213.2 185.9 267.4 235.4 418.7 C11orf49 "FLJ22210, MGC4707" ENSG00000149179 "Chromosome 11 open reading frame 49" Q9H6J7 11 46936689-47164385 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 140.0;Excitatory neurons: 140.8;Inhibitory neurons: 112.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040051, HPA040280" Uncertain Approved "Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear speckles" "HPA040051: AB_10795412, HPA040280: AB_10795363" "unprognostic (3.11e-2)" "unprognostic (3.01e-1)" "unprognostic (2.15e-1)" "unprognostic (1.06e-2)" "unprognostic (6.65e-2)" "unprognostic (7.76e-2)" "prognostic unfavorable (2.18e-5)" "unprognostic (1.27e-1)" "unprognostic (2.76e-1)" "unprognostic (1.72e-1)" "unprognostic (2.14e-2)" "unprognostic (1.55e-1)" "unprognostic (1.54e-2)" "unprognostic (1.36e-1)" "unprognostic (1.11e-1)" "unprognostic (1.07e-1)" "unprognostic (5.34e-3)" 8.1 13.4 52.4 6.2 51.6 3.3 10.0 45.9 54.7 15.6 46.1 14.3 11.2 16.8 14.1 9.7 32.5 9.6 12.3 52.4 53.3 15.7 3.9 12.1 6.3 47.0 53.9 14.9 12.7 22.6 30.3 6.8 49.2 12.4 11.4 21.8 11.0 13.2 7.3 31.6 11.9 12.8 46.2 7.0 15.4 20.2 53.7 13.7 16.1 6.4 7.2 11.9 11.4 45.5 10.9 30.6 37.9 27.9 17.8 25.7 9.5 11.7 26.9 24.6 29.9 6.9 17.0 9.1 12.3 24.4 29.7 14.8 18.8 28.7 20.9 18.1 27.2 12.2 36.6 12.6 30.5 14.6 16.2 17.5 19.1 11.2 16.4 47.0 27.6 22.1 10.3 11.7 18.2 22.8 23.0 16.2 14.3 26.5 16.4 8.2 9.5 10.1 43.3 11.7 25.5 36.5 13.4 14.9 14.7 19.7 25.0 8.5 6.5 13.8 11.0 22.0 17.7 10.4 9.2 7.5 33.7 3.0 17.5 12.7 10.2 9.0 19.2 13.7 23.0 24.1 18.1 22.7 24.6 17.6 19.1 20.3 0.3 25.2 10.3 21.8 19.0 18.3 52.4 51.6 45.9 54.7 52.4 53.3 47.0 53.9 49.2 46.2 53.7 45.5 6.6 9.6 26.7 140.0 9.9 13.0 16.4 30.6 12.0 22.9 12.0 13.0 9.4 12.8 24.0 23.9 18.8 19.4 5.6 18.3 46.9 30.2 53.2 42.8 20.4 10.2 19.2 8.0 140.8 20.4 13.4 18.0 25.5 14.1 16.4 23.3 8.6 2.4 9.9 37.0 112.7 12.8 22.4 3.3 7.0 35.8 12.8 6.2 12.4 41.2 10.9 45.0 7.2 93.0 71.9 16.2 21.2 20.3 5.8 8.1 22.1 33.4 66.7 53.1 6.6 12.2 13.5 63.3 7.6 10.5 18.0 10.0 10.8 32.6 13.7 12.1 C12orf57 "C10, GRCC10" ENSG00000111678 "Chromosome 12 open reading frame 57" Q99622 12 6942978-6946003 "Disease related genes, Predicted intracellular proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046182, HPA059163, HPA066043" Approved Enhanced "Nuclear speckles" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Nuclear speckles" "HPA046182: AB_2679572, HPA059163: AB_2683937, HPA066043: AB_2685603" "unprognostic (5.89e-2)" "unprognostic (1.56e-2)" "unprognostic (2.36e-2)" "unprognostic (1.80e-2)" "unprognostic (2.24e-2)" "unprognostic (2.56e-1)" "unprognostic (5.20e-3)" "unprognostic (8.27e-2)" "unprognostic (1.11e-1)" "unprognostic (3.48e-2)" "prognostic favorable (8.74e-4)" "unprognostic (4.25e-2)" "prognostic unfavorable (2.32e-7)" "unprognostic (1.47e-2)" "unprognostic (3.26e-1)" "unprognostic (6.81e-2)" "unprognostic (8.39e-3)" 254.8 199.9 230.6 76.1 231.7 128.4 282.7 235.0 329.3 411.9 239.0 242.7 76.5 296.1 85.9 143.9 328.1 134.2 327.9 221.9 240.4 225.2 205.5 217.9 183.5 233.4 235.7 574.0 300.7 117.2 332.4 75.2 233.9 297.0 69.5 37.0 173.2 157.1 194.2 307.1 163.3 85.2 227.6 160.7 220.3 82.1 252.6 262.6 214.2 179.8 77.0 263.9 270.0 236.8 88.3 253.6 291.0 288.0 196.6 233.8 96.1 113.7 277.0 96.4 153.0 101.4 146.8 27.0 88.1 178.1 124.4 83.6 111.2 140.6 23.1 158.1 232.8 234.8 191.4 145.2 372.3 96.9 220.7 281.9 164.7 74.6 101.7 188.8 164.2 216.5 82.2 230.3 90.5 264.3 204.6 124.8 522.0 146.3 92.2 224.4 259.7 404.8 131.2 218.8 128.9 377.5 182.8 184.3 242.6 136.7 46.8 501.1 174.3 192.7 181.8 77.9 173.0 169.8 150.0 149.8 198.6 2.4 132.2 75.7 20.0 19.3 187.8 34.2 123.6 133.2 208.5 199.6 29.5 163.8 248.0 203.7 7.9 99.9 87.0 225.2 204.5 160.1 230.6 231.7 235.0 329.3 221.9 240.4 233.4 235.7 233.9 227.6 252.6 236.8 260.9 64.1 129.2 11.1 256.4 264.5 285.2 255.3 546.9 90.6 284.2 624.3 219.4 211.6 146.0 123.2 25.0 131.4 216.3 262.8 365.9 191.9 175.7 122.1 336.7 206.8 312.1 81.6 7.4 423.9 219.4 340.3 179.4 146.9 148.9 86.2 204.9 307.0 67.2 37.0 11.0 686.2 162.8 88.9 138.1 299.5 453.3 120.2 231.3 15.0 58.4 197.5 200.8 7.1 8.9 205.5 240.0 377.3 216.6 279.5 146.8 244.4 89.0 94.9 289.3 389.2 473.4 75.1 86.0 301.7 215.0 154.2 328.2 157.0 349.5 215.6 C16orf70 "C16orf6, FLJ12076, lin-10, LIN10" ENSG00000125149 "Chromosome 16 open reading frame 70" Q9BSU1 16 67109941-67148544 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 57.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 47.9;Oligodendrocytes: 41.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041131, HPA041214" Approved Approved "Nucleoli fibrillar center,Nuclear speckles,Cytosol" No No "Cluster 14: Monocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" "Nuclear speckles" "Nucleoli fibrillar center, Cytosol" "HPA041131: AB_10795487, HPA041214: AB_10794267" "unprognostic (1.30e-2)" "unprognostic (2.58e-2)" "unprognostic (1.18e-1)" "unprognostic (1.34e-1)" "unprognostic (2.00e-1)" "unprognostic (3.23e-2)" "unprognostic (1.32e-1)" "unprognostic (1.10e-1)" "unprognostic (1.91e-1)" "unprognostic (2.25e-1)" "unprognostic (3.74e-3)" "unprognostic (1.81e-2)" "unprognostic (6.29e-2)" "unprognostic (1.07e-1)" "unprognostic (4.38e-2)" "unprognostic (1.68e-1)" "unprognostic (2.15e-2)" 11.3 10.0 15.6 7.6 16.6 18.1 11.1 15.5 17.4 13.2 10.8 10.2 7.3 11.2 8.9 17.8 10.6 7.5 10.3 18.5 13.6 14.0 57.3 9.8 9.2 15.7 16.1 11.1 8.3 16.1 10.9 11.8 17.0 14.4 10.1 8.1 12.0 8.5 29.7 30.4 10.0 10.8 16.2 14.7 8.6 13.8 15.6 9.2 9.0 15.3 11.7 10.5 14.6 21.4 13.7 19.3 19.0 19.9 23.6 13.9 44.5 15.4 16.6 30.7 33.3 22.1 11.7 13.9 13.3 18.2 16.9 18.0 23.7 14.9 39.7 7.1 19.7 10.6 12.2 47.4 14.5 10.9 58.0 14.1 20.6 30.2 13.9 16.6 17.3 17.5 17.5 5.8 19.4 13.6 21.2 16.6 21.5 18.4 29.4 29.5 32.2 21.9 13.4 8.2 24.5 13.2 46.2 10.7 12.0 18.7 22.0 9.0 13.4 21.5 18.4 15.5 13.5 8.8 17.3 41.3 19.4 10.9 17.5 3.2 17.4 6.1 4.4 12.2 5.9 6.9 6.6 8.1 14.6 4.5 6.8 6.3 6.2 5.9 13.6 4.8 7.2 8.9 15.6 16.6 15.5 17.4 18.5 13.6 15.7 16.1 17.0 16.2 15.6 21.4 5.1 6.4 5.9 11.1 6.6 9.1 2.5 5.1 19.4 7.4 8.7 6.7 1.3 1.5 3.2 0.0 0.0 8.8 5.0 4.9 5.9 4.4 1.6 12.9 8.5 6.2 7.2 11.1 20.4 2.9 9.5 5.1 8.6 30.6 9.5 8.7 5.0 47.9 18.6 10.1 18.5 8.4 4.1 13.5 7.8 1.6 4.7 13.2 10.6 17.8 13.3 2.7 3.1 11.1 41.6 4.8 8.6 6.4 7.5 4.6 5.4 10.3 11.0 5.9 13.1 5.3 6.4 24.7 24.8 20.5 12.1 7.0 6.7 8.2 5.7 1.3 C16orf71 "DKFZp686H2240, FLJ43261" ENSG00000166246 "Chromosome 16 open reading frame 71" Q8IYS4 16 4734344-4749396 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "fallopian tube: 22.5;testis: 74.0" "Cell type enhanced" "Detected in some" "Early spermatids: 37.1;Late spermatids: 62.0;Respiratory ciliated cells: 22.6;Spermatocytes: 122.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "MCF7: 4.6;U-2197: 5.0" "Low region specificity" "Detected in all" HPA049468 Enhanced Uncertain "Nuclear speckles" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 6: T47d - Mammary gland" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" "HPA049468: AB_2680779" "unprognostic (1.24e-2)" "unprognostic (8.87e-2)" "unprognostic (2.39e-1)" "prognostic favorable (7.49e-4)" "unprognostic (7.06e-2)" "unprognostic (2.17e-2)" "unprognostic (5.36e-3)" "unprognostic (2.21e-2)" "unprognostic (1.69e-1)" "unprognostic (2.15e-2)" "unprognostic (6.79e-3)" "unprognostic (1.13e-1)" "unprognostic (8.56e-3)" "unprognostic (1.57e-1)" "unprognostic (1.61e-1)" "unprognostic (2.54e-5)" "unprognostic (1.65e-1)" 0.7 1.3 1.0 0.7 1.4 0.2 0.7 2.2 1.6 1.4 9.2 0.8 0.6 1.0 2.7 0.7 22.5 1.4 0.8 1.5 1.4 1.8 1.3 2.8 0.4 4.5 5.7 1.2 1.1 0.9 4.1 0.2 2.6 1.1 0.3 1.7 1.2 0.7 1.0 0.5 0.4 0.8 3.3 0.4 0.8 74.0 1.5 0.6 2.0 1.1 0.4 0.7 0.5 1.6 0.3 2.0 0.4 1.1 2.6 1.1 0.8 1.1 0.9 0.9 1.1 0.9 0.8 0.0 1.0 1.6 2.6 0.9 0.9 1.1 0.2 0.4 0.6 0.2 1.5 0.1 0.8 0.9 0.3 0.3 0.2 3.4 0.9 0.7 0.4 0.8 0.7 0.5 0.9 4.6 0.2 0.8 0.6 1.3 1.0 0.3 0.4 1.4 2.3 0.4 3.0 1.1 1.1 0.9 0.3 0.7 4.0 0.2 0.4 0.7 0.8 5.0 0.5 2.0 1.7 0.5 0.4 0.2 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.4 0.1 0.1 0.0 0.0 0.3 1.1 0.0 0.1 1.0 1.4 2.2 1.6 1.5 1.4 4.5 5.7 2.6 3.3 1.5 1.6 0.1 0.0 1.1 1.0 0.1 0.0 0.2 1.0 0.6 0.9 0.6 0.5 1.2 0.0 3.9 0.0 4.2 0.3 0.2 0.2 0.0 0.6 37.1 15.6 0.6 0.2 0.0 0.0 1.0 0.0 0.1 0.3 3.6 0.6 0.0 0.2 0.0 0.3 0.2 0.0 0.9 0.1 0.0 0.0 0.0 62.0 1.2 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.7 0.0 0.0 1.5 0.0 0.1 0.0 2.4 22.6 1.7 0.0 0.2 0.7 122.1 7.2 0.5 0.0 0.1 0.2 0.3 0.3 0.0 C1orf127 FLJ37118 ENSG00000175262 "Chromosome 1 open reading frame 127" 1 10946471-10982037 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "pancreas: 4.4;skeletal muscle: 16.5" "Cell type enriched" "Detected in some" 9 "Enteroendocrine cells: 20.4" "Cancer enriched" "Detected in single" 9 "pancreatic cancer: 2.8" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.3" "Lineage enhanced" "Detected in single" "dendritic cells: 1.3" "Cell line enriched" "Detected in single" 4 "THP-1: 2.6" "Not detected" "Not detected" HPA027654 Uncertain Approved "Nuclear speckles,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 43: THP-1 - Innate immune response" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Nuclear speckles, Cytosol" "HPA027654: AB_10611814" "unprognostic (1.82e-2)" "unprognostic (8.57e-2)" "unprognostic (1.62e-2)" "unprognostic (1.05e-1)" "unprognostic (1.17e-2)" "unprognostic (2.03e-2)" "unprognostic (3.81e-2)" "unprognostic (1.32e-2)" "unprognostic (9.93e-2)" "unprognostic (1.21e-1)" "unprognostic (1.82e-2)" "unprognostic (8.47e-2)" "unprognostic (1.59e-2)" "unprognostic (3.31e-1)" "unprognostic (1.34e-1)" "unprognostic (1.04e-1)" "unprognostic (4.03e-1)" 0.2 0.6 0.3 0.1 0.3 0.1 0.1 1.2 0.7 0.1 0.2 0.3 0.7 0.0 0.1 0.6 0.0 0.3 0.6 0.2 0.3 0.0 0.2 0.4 0.6 0.2 0.5 0.0 4.4 0.1 0.2 0.2 0.3 0.1 0.6 0.0 0.2 0.0 16.5 0.0 0.3 0.0 0.2 0.6 1.9 0.5 0.7 0.1 0.2 3.7 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.1 0.0 0.0 2.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.3 1.2 0.7 0.2 0.3 0.2 0.5 0.3 0.2 0.7 0.3 0.0 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 20.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.3 0.8 0.0 0.8 0.6 0.1 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 C1orf194 ENSG00000179902 "Chromosome 1 open reading frame 194" Q5T5A4 1 109105951-109113857 "Disease related genes, Predicted intracellular proteins" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "fallopian tube: 106.5;testis: 147.9" "Cell type enhanced" "Detected in some" "Early spermatids: 2151.8;Endometrial ciliated cells: 931.5;Late spermatids: 3412.7;Respiratory ciliated cells: 808.8;Spermatocytes: 514.1" "Group enriched" "Detected in many" 6 "endometrial cancer: 19.1;glioma: 5.0;ovarian cancer: 5.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "eosinophil: 2.1" "Lineage enriched" "Detected in single" 16 "granulocytes: 2.1" "Cell line enhanced" "Detected in some" "AF22: 1.5;SCLC-21H: 2.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA031144, HPA049684" Enhanced Uncertain "Nuclear speckles,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 49: Ciliated cells - Cilium organization" "Nuclear speckles" Cytosol "HPA031144: AB_10602109, HPA049684: AB_2680849" "unprognostic (9.91e-3)" "unprognostic (7.60e-3)" "unprognostic (2.28e-2)" "prognostic favorable (1.36e-4)" "unprognostic (3.03e-1)" "unprognostic (1.14e-2)" "unprognostic (4.53e-1)" "unprognostic (3.91e-3)" "unprognostic (5.27e-2)" "unprognostic (9.21e-3)" "unprognostic (3.98e-3)" "unprognostic (1.52e-1)" "unprognostic (6.08e-6)" "unprognostic (4.18e-2)" "unprognostic (4.53e-2)" "unprognostic (5.94e-3)" "unprognostic (3.27e-3)" 0.0 0.1 1.7 0.0 1.9 0.0 0.2 2.1 2.8 2.1 14.0 0.4 0.3 1.1 1.2 0.1 106.5 0.0 0.1 2.3 1.8 0.2 0.0 4.4 0.0 3.3 3.3 0.1 0.9 0.2 2.4 0.0 2.8 0.3 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.1 2.1 0.0 0.3 147.9 2.2 0.3 0.3 0.0 0.0 0.3 0.0 2.3 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.7 1.9 2.1 2.8 2.3 1.8 3.3 3.3 2.8 2.1 2.2 2.3 0.0 0.0 4.1 0.7 0.2 0.0 0.2 53.9 0.0 0.6 0.8 0.9 3.5 0.0 61.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2151.8 931.5 6.1 1.8 0.0 0.0 1.1 0.2 0.0 0.7 0.0 11.2 3.8 0.0 0.0 0.0 0.1 0.0 1.0 0.4 57.0 0.0 0.3 3412.7 21.1 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 18.8 0.0 2.4 0.0 0.8 808.8 0.0 6.6 0.2 9.0 514.1 20.2 0.0 0.1 0.0 1.1 0.0 0.2 0.4 C1orf35 "MGC4174, MMTAG2" ENSG00000143793 "Chromosome 1 open reading frame 35" Q9BU76 1 228100726-228105411 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046175 Approved Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 27: Brain & Skin - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nuclear speckles, Plasma membrane" Cytosol "HPA046175: AB_10959459" "unprognostic (1.12e-1)" "unprognostic (2.91e-1)" "prognostic unfavorable (7.71e-4)" "unprognostic (6.41e-2)" "unprognostic (1.21e-1)" "unprognostic (2.64e-2)" "unprognostic (5.44e-3)" "unprognostic (1.81e-1)" "unprognostic (1.39e-1)" "prognostic favorable (7.38e-4)" "unprognostic (6.12e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (1.79e-6)" "unprognostic (2.70e-1)" "unprognostic (8.58e-2)" "unprognostic (5.56e-2)" "unprognostic (3.70e-2)" 11.3 12.5 20.6 6.3 20.4 14.3 11.7 19.5 24.4 15.5 18.2 13.4 7.9 13.4 5.5 18.8 13.0 4.0 9.4 20.5 20.3 11.2 11.6 8.6 9.0 20.8 19.7 16.1 12.9 7.4 9.9 7.1 20.6 14.2 3.9 2.7 12.5 8.5 9.6 19.6 10.5 5.0 19.2 10.8 12.3 7.5 20.3 9.2 12.1 3.5 7.3 14.4 14.7 21.0 22.2 24.3 17.0 10.9 8.2 8.3 40.0 16.8 7.4 14.6 10.9 24.1 22.2 22.7 35.6 6.6 10.3 25.4 16.0 16.6 5.3 24.6 76.7 13.9 20.1 23.1 13.3 32.0 16.7 7.6 19.5 14.3 13.1 9.2 16.1 26.1 35.2 13.3 10.7 27.8 42.0 44.4 34.4 28.5 55.6 32.1 24.2 36.4 13.6 18.2 28.1 27.2 16.0 29.4 23.3 4.5 31.0 29.2 15.1 11.8 18.1 32.7 37.2 23.9 12.7 21.6 14.2 18.3 19.2 14.9 29.0 43.3 28.2 35.9 35.2 37.2 31.1 30.7 37.6 29.9 36.1 30.2 4.7 35.9 34.9 49.3 34.7 17.5 20.6 20.4 19.5 24.4 20.5 20.3 20.8 19.7 20.6 19.2 20.3 21.0 37.7 22.4 22.4 10.4 29.8 66.8 35.5 58.5 47.3 51.4 41.1 50.9 18.1 28.6 31.0 38.6 18.8 76.2 49.8 61.6 45.0 38.0 4.4 28.2 31.7 33.9 26.3 57.4 12.9 39.5 59.3 34.3 25.0 43.7 24.7 36.9 32.2 24.4 40.4 47.1 10.1 58.8 54.9 24.2 72.7 5.5 51.3 29.8 32.0 2.8 32.4 42.5 30.9 9.5 14.3 37.5 43.5 46.6 28.1 37.4 47.8 38.3 25.1 54.5 65.7 31.6 44.7 44.0 50.0 54.1 80.6 28.3 47.2 28.0 56.6 25.8 C3orf62 FLJ43654 ENSG00000188315 "Chromosome 3 open reading frame 62" Q6ZUJ4 3 49268596-49277232 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 51.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 8 "neutrophil: 40.0" "Lineage enriched" "Detected in many" 8 "granulocytes: 40.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043328 Approved "Nuclear speckles" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 71: Testis - DNA repair" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" "HPA043328: AB_10795613" "prognostic favorable (3.93e-4)" "unprognostic (4.87e-3)" "unprognostic (3.70e-3)" "unprognostic (2.35e-2)" "unprognostic (9.51e-2)" "prognostic favorable (9.72e-4)" "prognostic unfavorable (5.20e-4)" "prognostic favorable (8.88e-4)" "unprognostic (1.28e-1)" "unprognostic (9.40e-3)" "prognostic favorable (8.15e-4)" "unprognostic (7.23e-2)" "unprognostic (3.27e-2)" "prognostic favorable (3.29e-5)" "unprognostic (2.46e-1)" "unprognostic (4.79e-1)" "prognostic favorable (1.62e-5)" 6.5 10.5 3.0 4.5 3.6 8.5 5.5 4.4 5.5 6.1 7.0 7.6 3.1 5.6 4.5 6.9 7.9 4.8 6.5 3.5 4.0 5.7 5.6 7.3 4.9 3.8 3.4 11.3 3.2 3.1 7.8 2.7 4.2 7.5 2.6 9.0 4.2 2.1 3.9 5.7 5.5 2.7 2.2 11.7 4.0 17.3 5.0 4.2 6.0 3.6 3.4 6.4 6.1 4.4 4.3 2.5 5.9 7.4 4.7 4.0 3.3 2.5 4.2 2.2 3.2 3.6 3.2 8.5 3.8 3.9 4.6 3.3 2.9 2.8 2.4 7.5 3.4 5.6 5.8 4.0 1.4 8.0 10.0 3.3 8.1 3.2 6.0 3.8 2.5 4.9 6.5 6.3 1.8 2.7 5.9 5.8 4.2 3.6 3.6 4.4 3.1 4.5 3.6 9.8 4.5 6.1 6.8 5.2 9.1 4.3 2.6 8.8 3.1 3.0 7.3 5.2 4.7 5.5 10.2 7.1 2.2 7.4 4.2 1.0 5.1 5.3 1.2 1.7 1.0 1.9 1.1 1.2 0.6 1.2 0.8 1.0 40.0 0.3 1.7 2.5 1.4 1.3 3.0 3.6 4.4 5.5 3.5 4.0 3.8 3.4 4.2 2.2 5.0 4.4 8.6 9.6 16.1 4.6 4.4 6.8 3.5 7.9 1.8 12.6 5.7 6.0 9.1 7.2 10.3 11.0 22.9 7.0 7.8 7.6 0.0 4.9 12.4 6.6 9.2 8.1 5.4 7.0 7.3 3.9 4.3 7.3 5.6 10.1 2.5 8.5 9.7 6.3 9.8 5.0 6.1 9.8 2.0 18.0 7.1 17.3 8.7 11.3 8.8 9.4 14.2 7.3 9.2 4.5 7.0 6.0 3.8 8.6 4.6 7.0 4.9 5.2 11.1 13.7 0.0 14.9 6.4 51.8 6.8 4.2 8.7 4.1 6.9 12.1 7.4 2.7 C5orf46 "MGC23985, SSSP1" ENSG00000178776 "Chromosome 5 open reading frame 46" Q6UWT4 5 147880726-147906538 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "salivary gland: 181.8;skin 1: 113.1" "Group enriched" "Detected in some" 12 "Early spermatids: 320.9;Late spermatids: 189.9" "Cancer enhanced" "Detected in many" "renal cancer: 8.3" "Region enriched" "Detected in single" 10 "cerebellum: 2.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 54.2;PC-3: 90.8;SiHa: 20.2;U-2 OS: 58.2;U-251 MG: 23.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA058999, HPA079692" Supported Approved "Nuclear speckles,Mitochondria" "Secreted in other tissues" NA NA 54000 "Cluster 31: Skin - Epidermis development" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nuclear speckles" Mitochondria "HPA058999: , HPA079692: " "unprognostic (1.72e-1)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.26e-4)" "unprognostic (9.75e-3)" "unprognostic (2.95e-3)" "unprognostic (1.69e-3)" "unprognostic (1.99e-2)" "unprognostic (3.08e-2)" "unprognostic (2.22e-1)" "unprognostic (4.96e-2)" "unprognostic (2.86e-3)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.75e-9)" "unprognostic (6.48e-3)" "unprognostic (3.47e-2)" "unprognostic (6.01e-2)" "unprognostic (2.79e-2)" 0.4 0.0 0.0 0.0 0.0 0.0 13.5 2.3 0.1 1.6 0.7 0.4 0.0 0.1 0.4 0.4 0.0 0.2 9.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 2.2 0.2 0.9 0.0 0.6 181.8 0.1 0.8 113.1 0.0 3.2 0.0 0.0 0.0 19.2 0.0 0.3 0.2 0.1 0.3 0.0 3.6 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.0 2.4 1.4 0.0 0.0 0.4 0.0 0.0 0.1 0.0 1.0 0.3 0.0 0.6 0.0 0.2 0.2 0.0 4.6 0.2 0.0 0.0 0.0 0.0 1.1 0.0 8.9 54.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 90.8 0.0 0.5 0.0 0.0 0.1 0.0 0.0 20.2 0.3 0.3 11.1 0.0 0.0 0.0 10.0 58.2 0.8 23.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.8 0.0 0.0 9.2 3.7 11.0 15.7 0.2 1.8 0.0 0.5 0.2 0.0 0.0 15.9 320.9 0.7 0.4 0.3 0.0 0.0 0.0 3.3 0.6 0.2 0.0 3.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 189.9 1.8 0.2 3.6 0.0 0.6 7.7 0.0 0.0 0.0 4.2 0.0 0.4 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.0 2.1 1.1 0.8 0.0 20.6 1.4 0.1 0.0 0.0 0.2 C6orf226 LOC441150 ENSG00000221821 "Chromosome 6 open reading frame 226" Q5I0X4 6 42890265-42890821 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA045350 Approved Approved "Nuclear speckles" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 35: Non-specific - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" "Nuclear speckles" "HPA045350: AB_10964640" "prognostic favorable (1.93e-5)" "unprognostic (2.21e-3)" "unprognostic (2.91e-1)" "unprognostic (2.77e-3)" "unprognostic (1.71e-1)" "unprognostic (4.17e-2)" "unprognostic (5.40e-2)" "unprognostic (2.00e-3)" "unprognostic (8.82e-2)" "unprognostic (3.50e-3)" "prognostic favorable (5.13e-4)" "unprognostic (2.24e-2)" "prognostic favorable (3.35e-4)" "unprognostic (4.63e-1)" "unprognostic (3.97e-2)" "unprognostic (6.13e-2)" "unprognostic (5.82e-3)" 19.3 31.9 12.9 5.9 12.6 13.2 15.7 13.0 19.6 14.5 11.4 19.3 7.8 18.5 6.2 11.7 13.6 2.2 14.9 11.9 14.5 20.0 14.9 14.4 5.4 13.3 12.8 12.6 13.5 4.1 25.5 2.2 12.9 17.5 1.5 5.6 12.8 7.0 19.7 25.8 15.0 2.5 14.0 18.8 15.4 11.3 13.7 6.3 15.6 3.6 3.0 18.5 12.4 14.2 9.9 7.5 6.7 13.6 7.2 6.3 8.1 6.0 3.2 7.2 9.4 2.8 3.3 2.1 12.2 2.9 4.6 7.8 1.8 3.8 2.1 9.3 13.9 7.8 6.6 19.7 7.4 2.1 5.5 7.1 4.9 3.6 1.7 2.0 5.6 8.1 0.5 11.1 4.5 19.9 16.0 13.4 2.4 9.6 6.3 7.0 4.8 10.4 4.0 7.6 13.1 15.9 11.4 5.0 16.3 2.4 12.1 6.1 7.5 5.7 17.0 10.7 5.7 26.9 22.1 32.9 3.5 4.2 4.0 7.5 21.8 21.8 17.4 17.3 13.1 16.8 22.1 18.0 25.4 15.7 17.1 21.0 9.6 23.8 24.6 23.7 19.3 15.1 12.9 12.6 13.0 19.6 11.9 14.5 13.3 12.8 12.9 14.0 13.7 14.2 18.7 12.8 10.4 7.5 12.9 14.4 19.3 26.8 24.5 29.9 15.2 18.2 13.9 15.7 16.9 22.0 6.2 22.8 24.9 11.1 66.5 21.9 1.5 31.6 10.2 15.7 9.7 7.4 2.5 32.7 9.7 16.0 14.8 18.1 7.0 28.8 12.1 18.2 21.6 30.3 3.9 10.6 16.2 20.4 14.8 2.3 14.6 19.8 30.2 7.5 18.2 54.2 36.0 1.5 10.8 22.3 13.8 13.5 17.2 12.6 11.0 38.6 33.2 29.3 0.0 12.3 15.4 2.9 5.4 18.3 17.0 16.7 20.3 17.0 9.1 20.0 C6orf52 ENSG00000137434 "Chromosome 6 open reading frame 52" Q5T4I8 6 10671418-10694797 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "testis: 13.7" "Cell type enhanced" "Detected in many" "Early spermatids: 46.4;Endometrial ciliated cells: 44.9;Late spermatids: 27.3;Respiratory ciliated cells: 37.7;Spermatocytes: 36.1;Spermatogonia: 20.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 3.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "NB-4: 6.1;U-266/84: 6.4" "Not detected" "Not detected" HPA051142 Uncertain Approved "Nuclear speckles,Intermediate filaments" No No "Cluster 35: T-regs - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" "Nuclear speckles" "Intermediate filaments" "HPA051142: AB_2681359" "unprognostic (1.14e-2)" "unprognostic (2.21e-2)" "unprognostic (1.63e-1)" "prognostic favorable (6.50e-5)" "unprognostic (9.12e-2)" "unprognostic (2.96e-1)" "unprognostic (1.11e-3)" "unprognostic (1.67e-1)" "unprognostic (1.03e-1)" "unprognostic (2.23e-2)" "unprognostic (2.02e-1)" "unprognostic (1.17e-1)" "unprognostic (1.46e-2)" "unprognostic (2.17e-2)" "unprognostic (3.92e-2)" "unprognostic (9.31e-3)" "unprognostic (7.65e-2)" 1.0 1.8 2.2 0.5 2.2 0.3 1.1 2.3 4.0 0.7 3.1 0.8 3.3 0.5 3.5 0.6 3.3 0.2 0.6 2.2 2.5 4.4 0.7 1.0 0.4 2.6 2.7 1.1 2.2 0.3 2.0 0.2 2.6 2.0 0.3 0.8 0.8 0.5 0.5 1.3 0.7 0.3 2.4 0.7 1.6 13.7 2.3 0.5 0.8 0.2 0.6 0.6 0.5 2.8 1.0 2.0 1.8 1.7 0.6 0.0 3.3 0.3 0.0 0.2 0.4 2.7 1.6 0.2 2.9 0.0 2.8 0.2 1.8 0.0 0.6 1.2 4.5 0.8 0.5 0.5 0.0 1.2 0.5 0.3 2.6 0.7 1.0 0.4 0.0 1.9 3.6 0.3 0.7 6.1 1.5 6.1 1.9 1.4 2.3 1.3 0.4 0.9 0.8 0.5 3.8 2.1 0.8 0.5 3.9 2.3 0.2 1.0 0.7 1.4 0.5 1.0 1.4 2.6 6.4 1.4 2.3 0.9 1.6 0.0 0.2 2.4 0.6 0.5 0.2 0.2 0.7 0.6 0.5 0.3 0.3 0.3 0.3 0.7 0.3 0.4 3.1 0.3 2.2 2.2 2.3 4.0 2.2 2.5 2.6 2.7 2.6 2.4 2.3 2.8 0.7 0.0 2.7 3.3 1.2 1.5 2.0 4.2 0.0 1.6 3.2 3.7 1.3 1.5 2.6 3.7 2.1 2.9 0.2 1.6 5.9 4.1 46.4 44.9 0.9 1.9 3.0 0.0 0.9 6.1 2.3 1.1 2.0 2.5 0.0 0.6 1.4 1.9 1.2 1.7 1.0 1.2 0.0 0.3 1.0 27.3 2.1 0.6 3.6 0.0 1.6 3.3 1.0 0.0 3.5 2.8 2.7 0.0 2.5 2.0 1.3 9.6 37.7 0.9 0.0 1.1 2.1 36.1 20.4 0.6 1.4 1.4 0.4 0.4 1.7 1.0 CACTIN "C19orf29, fSAPc, NY-REN-24" ENSG00000105298 "Cactin, spliceosome C complex subunit" Q8WUQ7 19 3610645-3626815 "Predicted intracellular proteins" "Immunity, Innate immunity, mRNA processing, mRNA splicing" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042504, HPA042548" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Nuclear speckles" Cytosol "HPA042504: AB_10797501, HPA042548: AB_10794760" "unprognostic (1.18e-1)" "unprognostic (7.90e-3)" "unprognostic (1.09e-1)" "prognostic favorable (3.69e-5)" "unprognostic (5.93e-2)" "unprognostic (2.87e-3)" "unprognostic (3.38e-2)" "unprognostic (1.01e-2)" "unprognostic (3.84e-2)" "unprognostic (1.38e-2)" "unprognostic (1.17e-2)" "unprognostic (7.22e-3)" "unprognostic (3.88e-2)" "unprognostic (4.98e-3)" "unprognostic (5.78e-2)" "unprognostic (3.08e-2)" "unprognostic (5.55e-3)" 14.6 14.2 20.6 7.8 19.6 10.0 14.8 19.4 24.0 15.7 16.6 15.4 6.2 16.7 2.6 15.4 16.8 3.0 16.3 20.3 18.8 17.0 19.9 12.3 7.6 21.1 19.6 24.7 17.3 4.2 13.3 4.6 19.1 17.2 3.2 4.6 13.2 4.2 19.4 17.8 15.2 2.9 18.5 18.4 15.8 18.2 19.8 8.7 15.3 6.1 4.4 16.5 14.6 20.1 22.2 12.5 10.3 17.9 7.4 7.2 15.6 15.4 6.3 9.1 10.2 12.5 9.7 18.4 12.9 9.7 10.6 20.4 10.8 12.9 5.5 18.7 14.8 11.4 19.2 15.1 10.3 15.7 15.9 7.1 12.2 8.4 5.8 5.4 13.2 15.6 25.9 19.8 4.9 13.3 28.0 13.5 22.0 13.4 14.8 29.4 13.5 17.5 8.5 11.0 14.2 19.9 17.4 12.1 13.3 5.5 9.8 17.7 17.2 12.3 15.5 27.0 27.4 30.3 21.6 20.7 15.2 24.8 16.8 0.0 0.4 0.0 1.2 1.0 0.4 0.6 0.5 0.5 0.3 0.6 0.6 0.8 0.2 0.3 0.1 1.4 0.5 0.4 20.6 19.6 19.4 24.0 20.3 18.8 21.1 19.6 19.1 18.5 19.8 20.1 7.4 0.0 2.7 5.9 6.3 6.0 4.1 2.8 5.7 5.1 6.9 7.1 3.1 5.7 2.2 1.8 2.1 3.6 7.2 6.9 0.0 5.1 3.3 6.7 5.8 5.3 1.2 7.4 3.9 4.9 5.2 5.1 9.2 7.4 4.5 8.5 3.3 4.8 5.1 0.0 4.1 5.8 2.0 3.9 6.5 4.5 5.9 5.3 1.8 3.7 6.1 6.0 8.2 2.5 5.8 5.2 4.4 5.7 6.0 6.0 3.6 3.1 2.4 6.2 0.0 7.2 6.4 10.8 8.8 7.9 8.0 3.3 5.6 7.6 6.1 3.6 CBFA2T2 "MTGR1, ZMYND3" ENSG00000078699 "CBFA2/RUNX1 partner transcriptional co-repressor 2" O43439 20 33490075-33650036 "Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 128.3;Excitatory neurons: 114.7;Inhibitory neurons: 116.6;Oligodendrocytes: 166.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SH-SY5Y: 45.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060523, HPA072433" Supported Approved "Nuclear speckles" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 6: Brain - Smell perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Nuclear speckles" "HPA060523: AB_2684305, HPA072433: AB_2686520" "unprognostic (6.51e-3)" "unprognostic (3.29e-1)" "unprognostic (2.16e-2)" "unprognostic (1.91e-3)" "unprognostic (1.21e-1)" "unprognostic (8.37e-3)" "unprognostic (2.85e-3)" "unprognostic (3.90e-2)" "unprognostic (3.08e-1)" "unprognostic (3.89e-2)" "prognostic favorable (6.93e-6)" "unprognostic (7.83e-2)" "unprognostic (1.39e-3)" "unprognostic (9.40e-2)" "unprognostic (1.21e-1)" "unprognostic (2.24e-2)" "unprognostic (3.12e-2)" 6.4 4.8 11.3 5.8 11.6 5.5 6.6 9.0 13.8 11.8 4.9 11.9 7.5 7.5 5.0 9.2 8.4 4.1 7.6 13.1 11.7 7.5 7.5 8.5 6.6 10.5 9.7 11.6 7.0 9.1 9.7 4.5 11.5 16.8 9.1 15.4 8.2 5.8 9.6 12.1 10.6 5.9 7.5 8.9 8.8 11.1 11.8 8.9 10.7 5.7 6.3 9.5 10.6 17.7 6.8 6.5 9.3 6.8 9.2 7.0 9.5 4.1 4.9 5.5 4.6 13.8 6.3 7.9 8.4 5.7 12.3 9.0 5.4 6.8 4.8 3.3 4.1 10.9 6.5 8.3 5.8 4.5 9.0 5.9 8.9 5.7 7.9 6.8 4.9 8.1 6.2 5.1 4.8 6.1 9.6 7.6 3.2 8.3 7.1 7.5 10.3 8.3 6.3 9.7 30.1 45.1 20.7 8.0 6.7 9.4 7.5 6.9 5.3 13.1 5.9 8.9 5.0 9.3 11.0 4.5 6.7 4.1 4.2 4.2 1.1 1.2 2.1 1.0 1.9 2.7 2.2 2.7 0.5 2.7 1.3 1.8 2.2 1.2 0.7 1.5 1.9 0.7 11.3 11.6 9.0 13.8 13.1 11.7 10.5 9.7 11.5 7.5 11.8 17.7 9.9 12.8 21.7 128.3 17.8 19.1 12.9 9.3 26.2 29.9 15.9 11.3 11.4 7.2 11.1 12.9 45.9 12.8 12.7 17.1 1.9 8.5 12.0 14.4 11.6 11.8 90.4 11.6 114.7 6.4 11.4 14.1 19.4 17.1 1.3 16.3 11.4 8.1 9.4 13.5 116.6 50.1 14.2 11.0 13.7 14.9 14.0 8.4 17.8 59.0 12.1 10.9 17.5 74.4 166.9 9.4 15.6 12.8 19.1 21.8 14.4 5.4 11.4 38.5 13.1 12.5 11.9 24.1 18.1 20.4 15.3 8.9 19.5 7.5 18.9 15.2 CBLL1 "FLJ23109, HAKAI, RNF188" ENSG00000105879 "Cbl proto-oncogene like 1" Q75N03 7 107743949-107761667 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021773, HPA026699" Enhanced Supported "Nuclear speckles" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nuclear speckles" "HPA021773: AB_1846103, HPA026699: AB_1846104" "unprognostic (1.90e-2)" "unprognostic (2.25e-1)" "unprognostic (8.57e-2)" "unprognostic (3.79e-2)" "unprognostic (8.16e-2)" "unprognostic (7.20e-2)" "unprognostic (1.37e-2)" "unprognostic (3.96e-3)" "unprognostic (4.28e-2)" "unprognostic (2.16e-3)" "unprognostic (1.29e-1)" "unprognostic (1.31e-1)" "unprognostic (2.12e-3)" "unprognostic (9.12e-2)" "unprognostic (2.07e-1)" "unprognostic (1.09e-1)" "unprognostic (8.71e-2)" 11.2 8.1 3.1 12.5 5.3 40.0 15.1 7.8 9.5 12.0 3.0 11.3 9.5 13.5 8.4 11.3 11.2 8.7 10.4 4.2 5.8 10.0 11.2 10.3 16.1 4.1 3.7 14.3 11.7 14.1 5.1 12.0 4.1 16.5 11.1 14.4 8.9 12.7 29.0 10.7 10.3 13.4 3.0 14.2 9.2 19.7 3.7 20.2 13.8 21.0 17.8 11.9 7.2 6.6 27.8 31.1 23.7 30.7 21.7 18.6 16.2 20.5 21.6 22.8 22.5 21.4 27.9 40.6 28.5 23.5 37.6 19.3 33.4 25.0 31.0 28.4 21.1 32.5 23.0 18.2 24.9 49.1 30.9 19.6 22.7 30.7 33.0 17.6 23.8 27.8 53.0 33.3 22.4 48.0 66.5 34.4 34.4 23.3 21.3 30.6 25.4 42.0 17.4 25.5 25.4 39.6 30.7 44.9 23.4 27.7 15.1 24.7 23.4 35.0 25.0 33.4 32.0 53.0 62.3 64.1 21.3 29.8 30.3 88.8 31.1 53.3 39.5 32.0 58.2 39.0 61.9 45.8 36.9 39.8 41.8 40.0 48.9 55.1 38.0 20.1 92.6 48.4 3.1 5.3 7.8 9.5 4.2 5.8 4.1 3.7 4.1 3.0 3.7 6.6 18.2 19.2 11.0 6.5 29.6 23.6 16.7 10.5 27.3 12.2 15.9 13.7 16.4 17.2 10.7 3.7 4.2 10.3 27.6 9.9 7.9 9.7 12.4 15.6 19.8 13.5 16.8 39.1 13.9 10.8 9.5 12.6 10.7 13.7 13.3 16.6 12.5 11.0 10.7 10.1 13.1 8.0 8.2 23.3 12.4 5.4 9.3 15.1 19.6 15.9 15.0 7.6 25.7 10.1 20.5 10.1 15.0 11.7 17.3 16.2 8.5 11.2 8.9 14.4 19.7 13.2 14.5 27.2 14.3 19.5 19.9 10.3 27.3 9.5 10.0 18.4 CCDC181 "C1orf114, FLJ25846" ENSG00000117477 "Coiled-coil domain containing 181" Q5TID7 1 169394870-169460669 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 41.5;testis: 27.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 66.1;Cone photoreceptor cells: 66.7;Early spermatids: 289.9;Late spermatids: 69.3;Respiratory ciliated cells: 109.6;Rod photoreceptor cells: 89.4;Spermatocytes: 201.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "basophil: 1.0" "Lineage enriched" "Detected in single" 10 "granulocytes: 1.0" "Cell line enhanced" "Detected in many" "AF22: 7.1;GAMG: 7.4;NTERA-2: 13.8;SCLC-21H: 8.4;SH-SY5Y: 9.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027189, HPA027275, HPA027281, HPA027312" Enhanced Uncertain "Nuclear speckles" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 77: Retina - Visual perception" "Cluster 5: NTERA-2 - Transcription" "Cluster 49: Ciliated cells - Cilium organization" "Nuclear speckles" "HPA027189: AB_10599252, HPA027275: AB_10602172, HPA027281: AB_10601452, HPA027312: AB_10601349" "unprognostic (2.45e-1)" "unprognostic (2.20e-1)" "unprognostic (1.42e-2)" "unprognostic (1.54e-3)" "unprognostic (3.00e-1)" "unprognostic (5.97e-2)" "unprognostic (6.87e-2)" "unprognostic (2.15e-3)" "unprognostic (1.13e-1)" "unprognostic (6.82e-2)" "unprognostic (2.32e-2)" "unprognostic (2.50e-1)" "unprognostic (4.89e-4)" "unprognostic (4.03e-2)" "unprognostic (3.06e-2)" "unprognostic (1.18e-2)" "unprognostic (8.41e-2)" 0.4 2.5 7.4 0.5 7.9 0.5 0.4 8.4 11.9 3.1 14.2 0.7 0.2 3.6 1.9 0.4 12.3 3.6 1.9 7.7 10.3 6.2 0.1 1.8 0.2 8.0 9.0 6.3 3.8 12.1 18.2 0.1 7.6 2.0 0.2 41.5 0.4 2.0 0.2 0.6 0.4 2.0 7.5 0.1 1.6 27.6 8.9 0.4 0.5 0.3 0.1 1.2 1.0 7.1 0.2 0.3 7.1 0.1 0.2 0.2 0.2 0.1 0.0 1.8 3.7 0.1 0.2 0.1 0.1 0.0 7.4 0.1 0.3 0.0 0.3 0.2 1.6 1.8 0.2 0.0 0.0 2.0 0.1 0.7 0.0 0.4 0.0 0.1 0.1 5.7 0.1 0.1 1.3 0.1 4.5 0.0 13.8 0.1 0.0 0.0 5.9 0.1 1.1 0.0 8.4 9.9 0.0 0.3 0.5 3.7 0.0 0.0 0.5 1.4 4.4 0.2 6.4 2.1 2.0 0.0 2.8 0.1 5.5 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.4 7.9 8.4 11.9 7.7 10.3 8.0 9.0 7.6 7.5 8.9 7.1 0.2 3.2 4.7 6.8 0.0 0.0 0.2 2.7 0.6 66.1 0.8 0.4 6.3 0.0 22.5 9.2 66.7 0.0 0.2 0.1 15.6 1.2 289.9 47.0 1.9 1.5 19.2 2.1 16.2 1.6 0.0 3.1 0.0 1.7 1.3 4.5 0.7 0.0 0.1 25.2 13.1 0.0 6.1 0.0 0.0 69.3 3.1 0.5 0.0 5.6 0.0 23.5 0.0 8.5 3.9 0.7 0.0 10.5 0.0 0.1 0.0 16.2 109.6 89.4 6.6 13.1 3.4 201.8 41.1 0.4 0.0 0.1 0.4 4.0 0.0 0.5 CCDC32 "C15orf57, MGC20481" ENSG00000128891 "Coiled-coil domain containing 32" Q9BV29 15 40528683-40565057 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 80.5;Hofbauer cells: 72.0;Syncytiotrophoblasts: 81.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041688 Uncertain Approved "Nuclear speckles,Vesicles" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 34: Non-specific - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 7: Non-specific - Mitochondria" "Nuclear speckles" Vesicles "HPA041688: AB_10796779" "unprognostic (7.10e-2)" "unprognostic (1.04e-1)" "unprognostic (9.86e-3)" "unprognostic (2.30e-2)" "unprognostic (2.65e-1)" "unprognostic (4.25e-5)" "unprognostic (4.03e-2)" "unprognostic (3.39e-2)" "unprognostic (1.15e-1)" "unprognostic (4.70e-2)" "unprognostic (2.34e-1)" "unprognostic (1.23e-2)" "unprognostic (5.77e-2)" "unprognostic (3.72e-1)" "unprognostic (1.18e-1)" "unprognostic (2.20e-1)" "unprognostic (6.47e-2)" 16.0 20.5 16.2 17.0 14.8 20.2 15.5 13.9 18.1 16.0 16.9 17.3 17.0 14.6 17.3 9.3 18.2 17.8 18.1 18.3 17.1 22.8 13.0 14.2 28.7 16.1 17.6 25.0 17.9 20.0 13.6 21.3 18.6 13.9 19.8 15.1 13.0 14.9 15.5 10.3 14.9 15.4 15.6 21.5 18.0 8.3 18.2 19.4 20.9 11.1 25.8 19.2 12.1 16.2 15.4 10.8 14.1 22.8 28.8 29.9 8.4 12.0 17.8 20.9 21.8 16.4 20.9 5.6 32.9 18.0 30.2 28.3 13.8 13.8 14.8 35.0 16.2 62.6 18.1 20.6 19.6 24.0 31.5 25.4 14.1 16.3 11.0 19.8 26.7 22.0 35.0 36.9 16.1 13.3 11.2 20.4 5.6 35.3 13.6 19.1 18.5 19.1 39.6 36.3 15.8 15.5 17.9 18.5 9.3 16.6 19.6 43.4 29.8 19.5 17.0 34.1 17.5 21.1 21.1 18.4 20.7 37.2 27.8 58.2 32.4 33.9 32.6 34.2 25.9 147.1 35.6 35.3 43.0 167.2 35.8 30.7 34.0 29.1 35.7 57.6 50.6 42.1 16.2 14.8 13.9 18.1 18.3 17.1 16.1 17.6 18.6 15.6 18.2 16.2 32.1 12.8 13.4 0.0 24.6 0.0 0.0 0.0 0.0 0.0 18.6 20.8 0.0 0.0 9.9 20.2 0.0 80.5 19.6 0.0 29.4 27.0 0.0 22.7 13.7 10.2 0.0 0.0 0.0 29.2 32.5 11.3 0.0 14.4 6.3 15.5 0.0 0.0 72.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.0 10.3 0.0 0.0 0.0 0.0 38.3 0.0 0.0 7.8 0.0 0.0 30.0 12.4 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 81.4 10.1 35.0 0.0 0.0 CCNB3 ENSG00000147082 "Cyclin B3" Q8WWL7 X 50202713-50351914 "Predicted intracellular proteins" "Cell cycle, Cell division, Meiosis" Cyclin "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 4.8;testis: 5.9" "Cell type enhanced" "Detected in some" "Oligodendrocytes: 9.1;Sertoli cells: 13.1;Spermatocytes: 48.2;Spermatogonia: 12.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 1.7;GAMG: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA000496 Approved "Nuclear speckles" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nuclear speckles" "HPA000496: AB_1078605" "unprognostic (1.57e-1)" "unprognostic (1.99e-1)" "unprognostic (7.19e-2)" "unprognostic (1.06e-1)" "unprognostic (9.96e-3)" "unprognostic (8.11e-2)" "unprognostic (1.86e-1)" "unprognostic (1.82e-2)" "unprognostic (1.34e-2)" "unprognostic (1.48e-3)" "unprognostic (6.93e-2)" "unprognostic (2.50e-1)" "unprognostic (1.67e-1)" "unprognostic (4.73e-2)" "unprognostic (1.87e-1)" "unprognostic (4.51e-2)" "unprognostic (2.63e-2)" 0.2 0.3 0.4 0.0 0.8 0.0 0.2 0.8 0.9 0.0 0.2 0.1 0.0 0.0 4.8 0.1 0.2 0.1 0.1 0.4 0.6 0.6 0.4 0.3 0.1 1.0 0.9 0.1 0.4 0.1 0.7 0.0 0.9 0.1 0.1 0.5 0.1 0.2 0.5 0.3 0.1 0.0 0.6 0.3 0.4 5.9 0.8 0.2 0.3 0.0 0.1 0.1 0.1 1.4 0.1 0.5 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.4 1.7 0.5 0.3 0.1 2.3 0.1 0.2 0.1 0.1 0.4 0.5 0.3 0.0 0.0 0.4 0.4 0.3 0.2 0.0 0.1 0.3 0.0 0.1 1.2 0.0 1.3 0.4 0.0 0.2 0.0 0.2 0.2 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.3 0.1 1.1 0.1 0.1 0.7 1.2 0.3 0.2 0.3 0.2 0.7 0.2 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.8 0.9 0.4 0.6 1.0 0.9 0.9 0.6 0.8 1.4 0.0 0.0 0.0 1.6 0.4 0.0 0.1 0.1 0.0 0.6 0.2 0.1 0.4 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.2 1.6 1.2 0.2 0.2 0.0 0.0 0.5 0.2 0.0 0.1 2.0 0.2 0.0 0.1 0.4 0.9 0.1 0.0 0.4 0.1 2.0 1.0 0.3 1.3 0.3 0.6 0.0 1.9 0.0 0.2 5.2 0.0 9.1 0.1 0.1 0.0 0.4 0.1 0.0 0.3 2.0 0.4 13.1 0.3 0.1 48.2 12.4 0.4 0.1 0.0 0.3 1.7 0.1 0.0 CCNJL FLJ14166 ENSG00000135083 "Cyclin J like" Q8IV13 5 160249083-160345396 "Predicted intracellular proteins" Cyclin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 22.4;Alveolar cells type 2: 23.4;Intestinal goblet cells: 28.5;Paneth cells: 26.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 18.6" "Group enriched" "Detected in some" 17 "neutrophil: 12.7;NK-cell: 4.2" "Group enriched" "Detected in many" 85 "granulocytes: 12.7;NK-cells: 4.2" "Cell line enhanced" "Detected in many" "HBEC3-KT: 49.8;RT4: 28.0;WM-115: 38.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA049970 Approved Approved "Nuclear speckles" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 21: Non-specific - Transcription" "Cluster 17: WM-115 - Nervous system development" "Cluster 27: Mucus-secreting cells - Mucin production" "Nuclear speckles" "HPA049970: AB_2680974" "unprognostic (1.09e-2)" "unprognostic (2.36e-2)" "prognostic favorable (7.31e-4)" "unprognostic (1.50e-3)" "unprognostic (1.79e-1)" "unprognostic (4.31e-2)" "unprognostic (1.60e-4)" "unprognostic (1.26e-2)" "unprognostic (6.92e-2)" "unprognostic (3.09e-1)" "unprognostic (2.57e-1)" "unprognostic (1.75e-2)" "unprognostic (6.27e-3)" "unprognostic (6.63e-3)" "unprognostic (2.62e-1)" "prognostic favorable (7.10e-4)" "prognostic favorable (8.02e-4)" 0.9 3.8 1.2 1.6 1.2 1.4 1.3 18.6 3.1 2.6 1.3 7.8 1.3 0.7 0.6 1.0 1.3 0.7 5.7 4.7 1.2 4.0 0.7 7.8 0.4 1.8 2.0 5.4 0.2 0.1 3.8 0.9 2.1 1.4 5.8 1.5 4.8 1.3 0.2 0.5 3.3 0.8 1.4 7.5 7.2 12.2 2.2 2.6 4.2 2.6 1.1 3.4 1.5 1.3 3.9 20.8 16.4 0.2 0.0 0.0 0.0 0.0 0.3 1.9 0.8 7.9 16.8 0.0 13.2 0.2 13.9 5.9 2.3 49.8 1.3 0.0 0.3 6.0 7.3 6.8 0.2 0.0 0.2 0.0 4.2 2.7 11.9 9.9 12.7 5.8 0.1 0.0 5.3 2.7 0.0 12.1 11.5 0.0 7.8 3.4 4.6 1.7 12.6 28.0 4.7 10.5 2.9 3.7 17.1 6.2 9.9 1.1 14.9 2.6 13.8 0.0 9.8 0.0 0.0 0.0 0.0 0.0 38.3 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.7 4.2 0.0 0.0 0.0 0.2 1.2 1.2 18.6 3.1 4.7 1.2 1.8 2.0 2.1 1.4 2.2 1.3 0.6 22.4 23.4 9.4 0.0 0.3 1.8 3.8 0.0 0.7 1.0 2.3 4.8 0.0 6.8 3.7 0.0 0.0 4.5 4.4 5.9 2.7 1.0 0.5 1.4 2.6 2.4 0.0 0.7 0.2 0.0 1.2 1.1 1.4 1.3 11.5 2.2 0.2 0.1 0.0 9.3 28.5 8.2 0.3 0.3 3.6 2.1 2.1 5.4 2.8 0.6 8.3 14.4 1.5 0.7 1.7 26.8 2.6 0.5 1.3 4.3 0.2 1.5 0.1 0.0 0.7 1.9 0.5 10.0 0.4 0.4 0.0 2.2 11.2 4.6 2.4 CD2BP2 "LIN1, PPP1R59, Snu40, U5-52K" ENSG00000169217 "CD2 cytoplasmic tail binding protein 2" O95400 16 30350773-30355308 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041508, HPA061309" Enhanced Enhanced "Nuclear speckles,Cytosol" Yes No "Cluster 31: Non-specific - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 1: Pancreatic cells - Digestion" "Nuclear speckles" Cytosol "HPA041508: AB_2677523, HPA061309: AB_2684476" "unprognostic (5.66e-2)" "unprognostic (7.50e-3)" "unprognostic (1.47e-1)" "unprognostic (2.82e-2)" "unprognostic (1.65e-1)" "unprognostic (2.78e-1)" "prognostic unfavorable (1.84e-5)" "unprognostic (1.71e-2)" "unprognostic (1.16e-1)" "unprognostic (9.76e-2)" "unprognostic (2.30e-2)" "unprognostic (7.47e-2)" "unprognostic (2.09e-3)" "unprognostic (1.44e-1)" "unprognostic (3.22e-2)" "unprognostic (1.75e-1)" "unprognostic (1.66e-1)" 31.1 49.3 38.9 34.0 39.7 23.9 32.9 38.0 41.5 39.6 34.0 39.3 29.9 45.0 24.9 35.3 41.0 22.0 35.2 39.9 41.2 42.8 27.3 32.8 38.8 41.4 39.8 36.9 40.7 42.5 42.7 24.4 39.1 38.3 23.7 16.2 30.0 35.5 46.9 33.6 35.2 31.6 39.0 46.4 36.9 24.0 41.6 35.7 42.5 26.6 43.7 37.0 30.1 42.0 55.4 65.7 54.4 49.4 44.3 41.9 46.0 60.0 71.5 66.8 71.3 50.6 64.9 84.6 72.3 65.5 61.4 59.4 57.0 70.3 53.6 50.6 66.6 35.9 67.7 60.3 63.6 51.3 63.4 45.2 58.7 74.2 47.3 45.6 70.3 62.1 41.4 63.2 67.7 132.1 71.6 43.6 73.8 42.9 38.5 104.2 45.3 64.3 54.2 54.7 44.7 85.1 40.2 69.9 42.0 44.7 66.4 41.1 50.6 76.3 53.3 38.9 53.1 105.0 82.3 78.5 52.5 47.2 64.0 107.4 61.7 116.6 71.3 76.3 56.8 87.5 57.3 66.7 55.8 97.3 47.6 58.9 121.9 74.5 102.7 67.1 94.4 79.6 38.9 39.7 38.0 41.5 39.9 41.2 41.4 39.8 39.1 39.0 41.6 42.0 38.1 32.1 29.0 7.2 39.5 28.8 49.6 58.4 31.9 29.8 33.2 29.6 26.5 45.8 41.2 36.8 20.9 61.0 57.0 50.5 60.7 83.6 19.9 41.7 30.7 42.8 33.0 22.3 6.7 97.5 58.1 36.4 28.1 45.2 47.6 33.4 28.2 13.9 69.7 11.8 7.1 32.7 36.7 38.3 23.6 14.2 35.4 34.0 39.2 8.4 84.1 47.6 97.9 3.5 10.7 87.8 64.9 35.7 52.7 40.7 60.3 81.5 46.3 29.0 39.5 30.5 44.6 38.5 40.1 27.4 30.4 88.7 41.9 38.9 31.6 50.7 CDC25C "CDC25, PPP1R60" ENSG00000158402 "Cell division cycle 25C" P30307 5 138285269-138338355 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.8;lymphoid tissue: 8.9;testis: 18.1" "Cell type enhanced" "Detected in many" "Early spermatids: 41.4;Late spermatids: 42.1;Spermatocytes: 53.6;Spermatogonia: 13.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "CAB003800, HPA066991" Approved Enhanced "Nuclear speckles" No Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear speckles" "CAB003800: AB_562081, HPA066991: AB_2685760" "unprognostic (2.45e-3)" "unprognostic (5.89e-3)" "prognostic favorable (2.49e-4)" "unprognostic (9.72e-3)" "unprognostic (2.17e-1)" "unprognostic (1.53e-1)" "prognostic unfavorable (3.03e-6)" "prognostic unfavorable (4.38e-4)" "unprognostic (5.56e-2)" "unprognostic (2.08e-1)" "unprognostic (1.70e-3)" "unprognostic (1.00e-1)" "unprognostic (0.00e+0)" "unprognostic (5.04e-2)" "unprognostic (1.43e-1)" "unprognostic (2.59e-1)" "unprognostic (3.06e-1)" 0.2 0.2 0.2 2.1 0.2 5.8 0.7 0.3 0.3 0.3 0.2 3.4 3.0 0.4 0.2 1.4 0.2 0.2 0.1 0.2 0.2 0.1 0.5 0.3 3.2 0.2 0.3 0.0 0.4 0.1 0.1 1.2 0.2 0.2 4.1 0.1 0.3 0.1 0.0 1.4 3.0 0.8 0.1 0.9 1.1 18.1 0.2 8.9 0.1 0.0 4.6 0.5 0.5 0.2 27.9 11.0 38.4 28.9 0.9 3.6 9.9 16.4 17.5 36.2 50.3 27.3 52.8 13.3 13.8 10.1 40.5 14.9 31.7 25.9 34.9 11.1 21.5 9.6 15.0 21.2 0.3 6.3 10.0 0.8 0.9 22.0 18.0 3.8 24.6 28.9 14.8 24.2 22.9 15.5 19.3 16.7 9.7 22.3 12.2 11.9 34.2 15.0 6.4 8.4 19.2 11.9 36.8 11.0 16.9 32.6 18.7 13.9 7.2 19.9 16.8 13.9 26.5 15.0 13.4 13.0 8.3 14.3 15.6 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.6 0.1 0.2 0.2 0.3 0.3 0.2 0.2 0.2 0.3 0.2 0.1 0.2 0.2 0.1 0.0 0.0 1.3 0.9 0.6 0.3 1.1 1.8 0.0 0.9 0.8 0.3 0.0 0.2 0.0 0.0 5.0 0.5 1.8 0.0 0.1 41.4 0.4 0.9 0.6 0.0 9.5 1.3 0.0 6.9 1.1 3.6 1.2 0.0 5.5 1.4 0.4 2.7 0.0 1.0 3.9 2.0 0.6 0.5 42.1 1.8 1.2 0.0 1.0 0.6 0.0 0.0 1.0 0.3 0.0 1.4 0.4 4.5 0.3 0.9 0.1 0.1 0.0 0.0 0.2 0.9 53.6 13.0 4.3 0.4 1.4 0.6 0.2 4.9 0.6 CDC34 "E2-CDC34, UBC3, UBE2R1" ENSG00000099804 "Cell division cycle 34, ubiqiutin conjugating enzyme" P49427 19 531760-542092 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 249.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002382, CAB005109, CAB047311, HPA074334" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nuclear speckles" Cytosol "CAB005109: AB_2276050, CAB047311: , HPA002382: AB_1846370, HPA074334: " "unprognostic (4.65e-2)" "unprognostic (2.02e-1)" "unprognostic (1.41e-1)" "unprognostic (8.72e-2)" "unprognostic (2.84e-1)" "unprognostic (5.73e-2)" "prognostic unfavorable (7.57e-4)" "unprognostic (2.20e-1)" "unprognostic (3.11e-1)" "unprognostic (3.83e-2)" "unprognostic (2.09e-2)" "unprognostic (3.06e-2)" "unprognostic (3.02e-2)" "unprognostic (8.87e-3)" "unprognostic (9.68e-2)" "unprognostic (7.82e-3)" "unprognostic (3.33e-2)" 35.1 36.7 52.0 13.3 51.2 34.5 34.2 51.5 63.0 36.9 47.5 62.5 17.8 33.5 14.1 40.5 33.6 10.1 80.0 52.7 48.7 32.1 88.0 32.1 12.5 51.0 50.7 35.6 58.5 18.7 43.4 29.2 50.8 36.9 11.5 28.2 34.2 19.3 105.0 51.8 27.6 18.5 48.2 31.0 38.6 100.2 52.7 16.4 26.7 63.2 9.7 43.7 34.2 52.7 54.8 54.6 66.4 54.7 29.2 28.4 68.5 47.8 36.1 50.2 51.9 86.1 32.8 29.5 49.3 34.1 30.1 36.9 52.1 40.2 25.0 49.2 146.0 27.8 35.5 94.5 73.6 39.0 32.4 36.4 58.9 42.2 43.6 38.8 60.6 41.2 120.3 57.5 33.8 80.7 53.3 53.6 85.3 39.4 51.7 49.1 35.1 51.2 38.0 32.4 87.2 65.9 41.5 42.1 85.2 53.2 34.0 57.4 50.5 36.5 43.7 86.2 65.2 57.7 47.3 40.1 50.0 55.6 38.8 3.2 2.5 4.7 1.6 2.7 1.1 2.3 2.1 2.9 2.0 1.0 1.6 1.6 8.2 1.2 3.5 1.6 2.5 1.0 52.0 51.2 51.5 63.0 52.7 48.7 51.0 50.7 50.8 48.2 52.7 52.7 39.4 0.0 5.4 21.9 11.4 46.8 17.5 5.4 16.5 35.5 43.4 47.1 27.7 27.1 3.5 14.7 25.0 44.3 30.9 47.4 13.7 24.9 63.9 29.6 28.3 27.7 13.2 77.7 8.3 20.5 55.4 21.4 16.8 42.3 0.0 28.1 15.7 41.1 27.9 16.8 6.3 34.0 14.2 14.5 38.6 249.4 18.0 20.6 19.6 2.8 15.1 68.9 20.6 6.6 12.9 45.0 27.0 15.1 25.0 34.8 25.9 18.9 5.5 44.3 13.1 22.6 34.9 22.4 54.6 15.2 54.7 63.1 22.0 27.1 23.7 27.9 CDK11A "CDC2L2, CDC2L3, CDK11-p110, CDK11-p46, CDK11-p58, p58GTA, PITSLRE" ENSG00000008128 "Cyclin dependent kinase 11A" Q9UQ88 1 1702379-1724357 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 124.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 85.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB010467, HPA025061, HPA073626" Supported Supported "Nuclear speckles,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 11: Alveolar cells - Smell perception" "Nuclear speckles" Cytosol "CAB010467: AB_631212, HPA025061: AB_1846407, HPA073626: AB_2686619" "unprognostic (6.25e-2)" "unprognostic (8.32e-2)" "unprognostic (1.47e-2)" "unprognostic (2.74e-1)" "unprognostic (9.32e-3)" "unprognostic (3.54e-2)" "unprognostic (2.25e-3)" "unprognostic (7.97e-2)" "prognostic unfavorable (5.06e-4)" "unprognostic (1.28e-1)" "unprognostic (5.58e-3)" "unprognostic (3.07e-2)" "prognostic unfavorable (1.15e-6)" "unprognostic (1.97e-1)" "unprognostic (5.98e-2)" "unprognostic (1.54e-1)" "unprognostic (3.70e-2)" 17.7 17.0 14.9 24.8 15.3 41.7 17.7 18.7 16.2 22.2 14.9 25.0 29.3 19.4 8.8 15.7 20.6 9.4 13.5 14.3 15.8 15.5 18.6 27.4 23.3 15.9 14.6 20.3 17.2 9.3 18.5 12.5 15.4 20.3 14.7 13.1 16.8 7.8 26.0 19.8 36.7 8.8 12.9 36.7 20.3 21.6 15.1 17.0 20.0 7.6 13.8 17.8 19.1 16.4 26.6 16.3 18.7 16.9 20.5 14.5 13.4 25.4 14.3 18.7 20.1 21.9 30.1 31.8 15.2 10.0 19.8 27.1 14.3 15.0 14.3 25.4 19.4 28.8 42.6 20.4 13.3 29.6 45.9 17.1 10.7 13.5 12.2 20.3 22.2 21.4 35.7 27.4 11.1 15.5 19.0 33.4 18.1 18.4 16.0 27.7 19.0 18.9 12.3 13.0 17.7 22.6 25.0 36.3 37.9 7.6 20.4 19.4 22.7 24.3 18.5 10.9 17.2 38.0 31.1 35.3 9.8 33.1 7.2 64.1 16.7 22.0 14.5 9.0 12.1 19.3 12.4 10.7 5.6 19.5 12.0 9.9 85.3 12.0 11.6 33.3 10.9 3.5 14.9 15.3 18.7 16.2 14.3 15.8 15.9 14.6 15.4 12.9 15.1 16.4 27.7 51.3 59.0 5.9 33.9 14.0 16.0 12.5 22.2 33.0 11.3 10.4 1.0 14.3 38.3 14.7 27.1 16.2 54.1 28.8 9.8 19.7 37.6 18.0 24.2 26.4 9.1 29.0 5.3 15.3 22.6 16.6 52.5 21.8 84.6 18.9 18.5 15.6 12.2 40.4 5.0 29.1 12.2 12.2 26.9 16.3 35.4 28.5 10.6 2.8 25.6 16.1 44.3 4.5 8.7 25.9 51.0 21.4 42.7 16.3 62.0 11.7 34.5 42.4 13.1 21.3 19.1 124.0 93.7 15.3 14.6 30.5 48.1 16.5 23.0 14.3 CDK11B "CDC2L1, CDK11-p110, CDK11-p46, CDK11-p58" ENSG00000248333 "Cyclin dependent kinase 11B" P21127 1 1635225-1659012 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 174.6;Spermatogonia: 176.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA025061, HPA073626" Approved Approved "Nuclear speckles" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 59: Non-specific - Translation" "Cluster 20: HeLa - Mitochondria" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nuclear speckles" "HPA025061: AB_1846407, HPA073626: AB_2686619" "unprognostic (7.52e-3)" "unprognostic (4.85e-2)" "unprognostic (1.14e-1)" "unprognostic (2.02e-2)" "unprognostic (3.75e-2)" "prognostic favorable (1.14e-4)" "unprognostic (9.75e-3)" "unprognostic (1.14e-1)" "unprognostic (1.88e-1)" "unprognostic (1.48e-1)" "unprognostic (2.18e-1)" "unprognostic (1.14e-2)" "unprognostic (6.04e-2)" "unprognostic (8.45e-2)" "unprognostic (1.27e-1)" "unprognostic (7.19e-2)" "unprognostic (6.52e-3)" 31.8 29.0 20.6 17.6 20.8 43.0 30.0 18.1 20.9 32.4 16.6 46.1 25.6 35.9 5.8 30.3 31.6 9.9 39.6 18.3 20.2 28.2 32.1 41.0 19.5 21.2 19.8 33.4 35.0 8.9 30.5 10.6 20.7 31.7 9.4 9.0 28.4 12.7 85.9 39.3 44.6 10.4 20.4 47.7 34.5 49.8 20.8 13.2 30.8 17.8 10.6 37.9 30.8 21.6 47.2 36.4 21.9 17.4 17.8 12.0 30.6 43.7 18.8 24.0 20.8 41.3 43.7 40.8 43.9 18.7 16.9 35.4 18.6 22.0 18.4 36.3 40.4 43.9 68.9 36.1 24.1 50.4 44.3 16.1 15.8 26.2 19.9 14.1 24.5 42.3 51.9 26.9 14.4 31.0 47.9 42.5 38.9 13.8 43.7 46.9 43.4 33.5 12.7 16.6 28.3 36.4 40.3 36.7 42.3 15.0 25.2 33.4 37.4 29.8 33.0 22.7 43.0 60.5 58.7 85.6 37.4 55.9 23.2 7.2 3.3 5.3 6.1 2.8 2.7 3.3 3.8 3.6 2.8 3.7 4.1 3.1 13.8 4.4 3.2 5.1 3.2 1.6 20.6 20.8 18.1 20.9 18.3 20.2 21.2 19.8 20.7 20.4 20.8 21.6 35.2 19.2 43.1 13.7 42.9 14.4 19.5 10.2 25.6 32.0 22.2 18.3 42.9 30.0 31.7 27.6 20.9 27.7 44.7 86.6 9.8 33.3 39.7 28.1 34.2 32.3 28.8 25.0 14.1 35.2 31.5 25.1 48.9 36.3 55.6 24.1 25.7 38.6 20.5 15.2 12.3 73.8 10.2 30.1 14.5 25.6 28.9 33.9 5.4 15.0 36.3 20.5 76.2 10.1 18.2 37.4 93.3 26.7 54.7 19.6 95.4 19.2 29.4 42.4 52.6 25.9 31.0 174.6 176.5 27.5 17.3 44.6 48.9 16.5 56.9 15.9 CDK12 "CRK7, CRKR, CRKRS, KIAA0904" ENSG00000167258 "Cyclin dependent kinase 12" Q9NYV4 17 39461486-39564907 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 307.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008038, HPA073305" Supported Enhanced "Nucleoplasm,Nuclear speckles" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nuclear speckles" "HPA008038: AB_1078570, HPA073305: " "unprognostic (2.02e-1)" "unprognostic (1.80e-1)" "unprognostic (2.61e-2)" "unprognostic (7.56e-2)" "unprognostic (1.05e-1)" "unprognostic (3.19e-1)" "unprognostic (2.56e-3)" "unprognostic (2.37e-2)" "unprognostic (3.86e-2)" "unprognostic (3.00e-3)" "unprognostic (6.87e-3)" "unprognostic (1.86e-1)" "unprognostic (3.06e-2)" "unprognostic (9.10e-2)" "unprognostic (1.24e-1)" "unprognostic (2.22e-2)" "unprognostic (5.32e-1)" 9.5 7.6 2.5 14.0 1.9 34.3 9.5 8.0 4.0 11.0 4.1 9.8 9.9 10.8 6.0 10.4 9.2 9.2 6.8 1.6 2.9 8.0 12.3 9.2 15.1 3.0 1.7 11.9 8.7 13.0 6.2 11.5 1.6 9.8 10.4 11.7 9.2 9.3 6.7 10.6 10.4 10.0 0.3 12.9 10.3 17.7 3.4 17.9 12.2 7.8 15.3 13.1 9.1 3.3 31.9 40.0 24.9 22.2 17.2 19.0 21.1 28.9 24.7 39.9 29.0 48.1 19.8 45.4 24.6 31.1 38.7 51.8 49.2 36.6 38.4 29.6 38.7 49.7 26.9 36.3 16.4 66.9 33.4 20.4 25.0 48.2 37.6 16.0 24.4 27.7 85.2 30.7 22.9 14.3 57.9 17.7 23.8 16.0 16.9 36.8 50.3 25.7 14.8 38.8 24.6 15.7 37.0 307.8 25.1 34.8 38.5 29.3 26.4 34.5 27.6 24.5 37.9 23.6 18.4 63.5 24.2 28.2 23.0 11.2 2.0 3.2 2.6 1.5 1.8 1.8 1.5 1.7 1.2 3.1 1.7 1.6 7.0 4.5 1.3 2.7 1.2 0.7 2.5 1.9 8.0 4.0 1.6 2.9 3.0 1.7 1.6 0.3 3.4 3.3 41.4 25.6 29.1 50.9 59.0 64.6 58.5 31.2 50.1 46.6 38.1 26.9 14.5 32.9 40.3 38.6 64.6 33.2 59.0 44.6 13.7 30.2 25.1 49.8 63.4 40.6 31.1 39.3 53.9 27.5 29.9 39.2 45.3 63.1 29.1 43.8 32.2 46.3 27.4 35.3 52.9 39.6 42.7 45.9 49.1 17.3 37.3 41.3 26.6 32.8 41.4 27.8 48.4 47.3 53.1 47.9 33.9 33.8 53.5 81.5 33.3 16.7 38.1 65.4 32.9 48.0 48.5 140.2 104.8 53.0 69.0 58.3 59.0 46.0 39.9 84.8 CDK13 "CDC2L, CDC2L5, CHED, KIAA1791" ENSG00000065883 "Cyclin dependent kinase 13" Q14004 7 39950121-40099580 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 179.0;Oligodendrocyte precursor cells: 171.9;Oligodendrocytes: 199.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059241 Uncertain Supported "Nuclear speckles,Golgi apparatus,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 34: Non-specific - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "Golgi apparatus, Cytosol" "HPA059241: AB_2683956" "unprognostic (1.99e-1)" "unprognostic (1.22e-2)" "unprognostic (2.67e-1)" "unprognostic (2.72e-1)" "unprognostic (1.83e-1)" "unprognostic (1.02e-1)" "unprognostic (4.18e-3)" "unprognostic (3.42e-2)" "unprognostic (8.09e-2)" "unprognostic (1.13e-2)" "unprognostic (3.77e-2)" "unprognostic (8.13e-2)" "unprognostic (8.20e-2)" "unprognostic (1.21e-1)" "unprognostic (3.33e-2)" "unprognostic (3.53e-1)" "unprognostic (3.53e-2)" 11.4 10.2 8.8 14.6 10.8 28.1 11.1 19.3 9.9 12.8 6.7 11.9 10.5 13.6 14.2 14.7 15.0 12.7 10.4 8.1 10.7 12.7 15.9 12.1 21.7 10.5 8.5 20.1 12.8 17.2 8.0 13.6 8.6 11.2 13.6 19.7 12.9 11.8 11.2 12.0 12.0 12.0 7.2 16.6 12.3 19.0 10.1 19.6 20.6 14.0 20.2 13.4 10.0 14.9 28.4 16.6 28.2 27.0 24.9 24.1 19.3 22.1 23.8 19.8 24.6 17.8 19.1 51.0 12.6 23.4 34.8 33.6 23.4 19.4 29.0 25.3 17.3 22.8 20.0 16.0 23.7 34.8 23.5 14.3 25.5 22.6 30.0 22.6 23.6 23.1 39.0 34.3 20.7 14.7 28.0 24.9 40.8 20.0 19.1 30.5 18.5 20.5 18.5 28.1 20.0 28.8 27.6 59.8 19.9 36.7 24.6 43.0 28.3 27.0 26.0 17.6 30.5 28.3 26.0 41.2 19.8 30.9 35.4 7.8 2.2 4.0 4.1 1.9 2.8 6.4 3.8 3.0 1.3 10.5 3.8 3.9 5.9 4.3 3.1 3.3 3.9 1.3 8.8 10.8 19.3 9.9 8.1 10.7 10.5 8.5 8.6 7.2 10.1 14.9 47.6 44.8 72.0 131.6 49.7 21.4 18.5 15.9 29.0 47.8 36.7 27.7 30.9 25.8 37.1 31.3 70.9 13.7 91.0 23.1 7.9 20.4 13.9 54.3 51.4 30.9 18.7 5.9 179.0 15.4 9.1 31.7 30.1 72.6 17.1 95.5 19.2 23.7 13.2 37.0 166.2 17.6 14.2 23.8 17.4 9.2 26.1 31.6 14.2 145.2 27.9 22.4 53.5 171.9 199.6 28.6 12.9 17.7 50.1 21.8 15.2 12.7 32.8 69.4 6.6 38.5 32.0 36.1 33.4 34.7 26.1 12.2 49.7 56.8 20.1 25.0 CDK5RAP1 "C20orf34, C42, CGI-05, HSPC167" ENSG00000101391 "CDK5 regulatory subunit associated protein 1" Q96SZ6 20 33358839-33401561 "Enzymes, Predicted intracellular proteins" "tRNA processing" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ionocytes: 128.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CACO-2: 116.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066301 Approved "Nuclear speckles,Mitochondria" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 39: CACO-2 - Unknown function" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles" Mitochondria "HPA066301: AB_2685653" "unprognostic (2.86e-1)" "unprognostic (7.19e-2)" "unprognostic (1.31e-1)" "unprognostic (1.66e-3)" "unprognostic (2.25e-1)" "unprognostic (6.49e-2)" "unprognostic (7.68e-3)" "unprognostic (2.18e-2)" "unprognostic (5.10e-1)" "unprognostic (2.36e-1)" "unprognostic (5.90e-3)" "prognostic unfavorable (8.07e-4)" "unprognostic (3.51e-2)" "unprognostic (8.13e-2)" "unprognostic (1.28e-1)" "unprognostic (4.87e-1)" "unprognostic (1.06e-1)" 9.1 8.4 4.9 10.7 5.7 18.6 10.5 4.9 5.3 8.4 6.3 9.0 8.9 9.8 11.5 9.3 9.2 6.2 12.0 5.7 4.3 9.0 11.1 9.0 12.7 4.5 4.4 8.6 7.6 11.2 7.2 10.3 4.1 8.4 12.2 15.9 10.6 8.7 20.9 12.6 9.5 10.8 3.9 10.3 9.7 9.3 4.6 11.3 11.9 22.8 15.2 8.7 7.9 4.9 27.0 27.6 18.6 17.1 17.4 13.4 40.7 15.8 22.5 45.0 46.9 116.5 23.9 47.3 21.0 17.2 29.0 39.1 31.8 45.1 34.8 8.9 17.3 57.1 30.8 45.1 20.3 36.6 17.4 17.5 18.9 30.2 35.9 11.4 24.9 13.6 36.7 19.3 20.0 26.6 37.8 27.5 14.1 30.2 40.1 27.8 42.4 36.1 24.5 23.6 25.2 14.3 50.5 24.4 33.0 20.9 34.7 17.4 18.4 33.3 27.3 23.1 27.4 16.6 20.1 34.8 19.8 39.3 15.9 4.5 17.3 11.8 18.5 22.3 22.2 21.4 18.3 18.0 19.1 14.1 16.2 14.0 0.9 21.6 18.4 13.4 17.3 15.1 4.9 5.7 4.9 5.3 5.7 4.3 4.5 4.4 4.1 3.9 4.6 4.9 13.2 16.0 20.0 26.8 18.6 12.1 10.3 21.1 10.8 25.6 9.3 8.9 15.7 11.5 18.6 7.3 27.1 31.4 18.2 7.4 13.7 17.6 2.9 10.1 10.3 11.4 12.6 12.2 36.7 18.3 18.5 10.4 13.3 14.6 29.8 15.6 6.1 15.6 17.5 11.8 25.4 8.6 128.1 10.1 12.6 2.8 13.1 13.5 10.6 10.3 15.2 16.5 19.6 16.1 26.6 13.0 9.0 10.5 19.3 8.3 13.8 15.3 20.9 39.9 19.7 14.8 15.3 32.6 23.6 8.5 10.4 16.0 22.3 16.1 12.6 8.9 CDX4 ENSG00000131264 "Caudal type homeobox 4" O14627 X 73447254-73455245 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 9 "skin 1: 1.1" "Cell type enhanced" "Detected in some" "Spermatogonia: 1.2;Suprabasal keratinocytes: 1.1" "Cancer enriched" "Detected in single" 11 "testis cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA043714, HPA056528" Uncertain Approved "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 61: Skin - Cornification" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nucleoplasm, Nuclear speckles" Cytosol "HPA043714: , HPA056528: AB_2683166" "unprognostic (1.97e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.2 0.0 1.1 0.0 0.0 0.0 0.0 0.0 CDYL "CDYL1, DKFZP586C1622" ENSG00000153046 "Chromodomain Y like" Q9Y232 6 4706159-4955551 "Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Lyase, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 6.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035578 Enhanced Supported "Nuclear speckles" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 52: Non-specific - Ribosome" "Cluster 44: HDLM-2 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nuclear speckles" "HPA035578: AB_2674685" "unprognostic (1.25e-1)" "unprognostic (8.99e-2)" "unprognostic (6.03e-2)" "unprognostic (2.38e-3)" "prognostic favorable (1.53e-4)" "unprognostic (1.92e-1)" "prognostic unfavorable (2.20e-4)" "unprognostic (2.62e-2)" "prognostic unfavorable (7.52e-4)" "unprognostic (2.06e-1)" "unprognostic (2.05e-2)" "unprognostic (2.09e-1)" "unprognostic (5.21e-3)" "unprognostic (1.90e-1)" "unprognostic (1.65e-1)" "unprognostic (2.60e-2)" "unprognostic (3.94e-1)" 14.0 6.0 6.9 10.2 6.8 20.0 11.5 5.0 6.7 15.0 4.9 13.0 7.0 15.2 10.5 16.8 10.6 8.4 10.4 6.0 6.4 7.2 5.6 8.9 12.1 6.6 6.2 9.9 7.5 12.4 5.1 18.2 6.0 7.6 13.2 6.7 9.0 11.9 19.5 17.8 9.0 14.5 5.6 9.6 9.2 9.0 6.7 9.3 9.7 12.7 12.9 15.6 13.0 6.9 23.7 22.1 30.1 25.5 23.3 15.9 34.4 23.1 17.9 21.3 22.9 18.0 17.2 5.3 22.1 17.6 33.3 19.8 24.2 28.2 24.9 16.4 20.2 20.9 21.0 16.4 28.5 27.9 21.7 12.5 49.8 25.0 37.5 12.9 20.6 19.2 37.9 16.2 10.8 22.9 14.8 25.9 32.6 17.9 21.3 19.0 26.2 43.7 14.7 20.5 25.5 15.4 28.5 24.9 36.9 86.5 15.0 26.3 28.1 25.2 21.6 18.5 26.8 33.7 57.8 18.4 8.3 17.7 28.1 5.3 1.3 0.6 1.5 0.6 1.1 1.0 1.1 1.2 1.6 1.1 0.7 1.1 0.4 1.6 0.8 6.8 0.1 1.3 6.9 6.8 5.0 6.7 6.0 6.4 6.6 6.2 6.0 5.6 6.7 6.9 32.7 19.2 9.4 28.7 18.4 37.3 23.9 11.9 10.8 16.7 31.2 35.8 18.8 14.3 12.0 14.7 22.9 12.9 64.5 44.7 15.6 10.8 62.8 26.9 43.2 22.9 32.3 41.5 52.3 10.4 22.0 18.7 6.1 60.3 5.7 24.3 18.9 11.7 10.5 45.4 41.5 26.6 6.1 17.3 57.9 74.9 5.9 28.1 8.8 101.2 22.7 25.4 19.6 54.3 64.1 16.8 41.8 8.2 22.3 30.1 4.6 10.7 12.1 25.7 6.6 29.7 20.9 10.4 25.3 9.8 41.9 63.8 17.5 10.9 22.6 56.9 CHD5 ENSG00000116254 "Chromodomain helicase DNA binding protein 5" Q8TDI0 1 6101787-6180321 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Differentiation, Neurogenesis, Spermatogenesis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 59.0;pituitary gland: 57.3;testis: 31.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 84.3;Early spermatids: 217.8;Excitatory neurons: 80.4;Horizontal cells: 225.4;Inhibitory neurons: 56.2;Late spermatids: 113.2;Rod photoreceptor cells: 49.9" "Cancer enhanced" "Detected in single" "glioma: 0.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "SCLC-21H: 12.9;U-2 OS: 5.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015809 Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Nuclear speckles" Cytosol "HPA015809: " "unprognostic (5.03e-4)" "unprognostic (1.89e-1)" "unprognostic (2.47e-3)" "unprognostic (9.40e-6)" "unprognostic (1.91e-2)" "unprognostic (2.98e-2)" "unprognostic (1.06e-1)" "unprognostic (1.09e-1)" "unprognostic (2.97e-2)" "unprognostic (1.95e-2)" "unprognostic (6.64e-4)" "unprognostic (1.34e-1)" "unprognostic (1.34e-4)" "unprognostic (1.16e-1)" "unprognostic (1.63e-1)" "unprognostic (1.96e-1)" "unprognostic (1.98e-1)" 0.2 4.1 31.8 0.2 40.1 0.0 0.1 0.0 59.0 0.4 0.0 1.1 0.2 0.4 0.0 0.3 0.4 0.1 0.4 34.3 13.6 2.4 0.1 0.3 0.0 3.9 11.1 0.5 0.4 0.9 57.3 0.0 4.4 0.9 0.2 7.9 0.2 2.2 0.2 0.3 0.4 0.1 0.9 0.1 1.0 31.8 10.2 0.3 0.1 0.0 0.0 0.7 0.6 31.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.6 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 2.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.2 1.2 0.0 0.1 0.2 1.1 0.0 0.0 0.0 0.0 12.9 0.2 0.1 0.0 0.0 0.0 2.3 0.0 0.0 0.1 5.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.8 40.1 0.0 59.0 34.3 13.6 3.9 11.1 4.4 0.9 10.2 31.1 0.0 0.0 0.0 5.5 0.1 0.1 0.1 0.0 0.0 84.3 0.1 0.3 2.1 0.0 0.0 3.7 12.5 0.0 0.1 0.2 0.0 0.0 217.8 0.0 0.2 0.6 0.0 0.0 80.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 225.4 56.2 0.0 0.0 0.0 0.3 113.2 0.9 0.1 0.0 2.8 0.0 2.0 0.0 4.5 3.7 0.3 0.0 0.4 0.0 0.2 0.0 0.1 0.0 49.9 0.0 0.2 0.5 4.5 17.8 0.0 0.4 0.0 0.1 0.1 0.0 0.0 CHIC1 BRX ENSG00000204116 "Cysteine rich hydrophobic domain 1" Q5VXU3 X 73563200-73687102 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Astrocytes: 47.0;Excitatory neurons: 62.7;Inhibitory neurons: 59.6;Microglial cells: 29.0;Oligodendrocyte precursor cells: 66.9;Oligodendrocytes: 76.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Karpas-707: 20.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026782, HPA052062" Uncertain Approved "Nuclear speckles,Vesicles,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nuclear speckles, Vesicles" Cytosol "HPA026782: AB_1846654, HPA052062: AB_2681714" "unprognostic (9.85e-3)" "unprognostic (3.91e-2)" "unprognostic (3.10e-2)" "unprognostic (9.95e-2)" "unprognostic (6.22e-2)" "unprognostic (1.91e-1)" "unprognostic (1.57e-1)" "unprognostic (1.36e-2)" "unprognostic (2.43e-1)" "unprognostic (1.25e-1)" "unprognostic (4.42e-3)" "unprognostic (2.65e-1)" "prognostic favorable (2.75e-4)" "unprognostic (1.37e-2)" "unprognostic (2.19e-1)" "unprognostic (3.51e-1)" "unprognostic (2.76e-2)" 2.9 7.0 4.4 3.0 4.8 0.6 3.7 4.6 8.5 7.1 2.4 5.2 2.3 5.6 3.8 2.4 4.2 4.6 5.4 5.7 6.1 6.3 1.5 2.7 3.9 5.9 4.6 5.7 2.2 5.9 5.6 2.1 6.0 4.8 4.2 5.4 2.8 5.1 2.6 3.0 3.4 5.4 4.9 4.1 2.5 1.5 5.8 2.8 6.5 5.2 3.5 4.2 3.4 5.1 4.6 4.7 2.3 3.0 6.5 8.7 0.0 5.1 6.8 4.1 4.9 3.1 5.8 2.1 6.9 4.6 8.1 1.4 3.3 2.5 9.0 5.3 4.1 3.2 4.0 0.0 4.2 0.0 6.0 6.1 2.9 7.7 4.1 5.2 5.9 2.1 0.8 20.3 8.1 0.7 1.9 0.0 7.3 0.0 4.6 1.8 5.9 1.3 5.1 2.3 1.3 1.9 5.8 2.7 6.3 3.9 2.3 1.3 6.9 4.7 4.6 9.4 3.1 5.7 15.3 0.0 6.9 3.4 3.7 0.2 0.0 0.0 0.4 0.0 0.7 0.2 0.3 0.4 0.0 0.2 0.3 0.4 0.0 0.3 0.0 0.0 0.3 0.1 4.4 4.8 4.6 8.5 5.7 6.1 5.9 4.6 6.0 4.9 5.8 5.1 8.3 3.2 9.1 47.0 9.4 2.7 4.6 2.7 4.6 10.0 4.2 3.6 12.7 5.7 4.1 3.7 6.2 0.2 7.5 2.1 0.0 3.5 4.1 10.9 5.6 9.4 0.0 4.4 62.7 3.5 0.0 8.2 1.5 7.3 5.1 5.3 5.3 1.6 1.6 13.5 59.6 7.5 2.0 2.2 1.8 1.8 3.1 2.3 5.4 29.0 1.6 5.7 8.2 66.9 76.1 2.4 6.1 9.1 6.7 5.4 1.4 11.4 3.9 7.5 0.0 8.3 5.0 2.0 2.4 2.4 4.5 0.0 8.8 5.9 3.4 4.6 CHRNA3 ENSG00000080644 "Cholinergic receptor nicotinic alpha 3 subunit" P32297 15 78593052-78621295 "Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "adrenal gland: 39.3;lymphoid tissue: 65.8;retina: 53.5" "Cell type enriched" "Detected in some" 19 "Cone photoreceptor cells: 164.7" "Cancer enhanced" "Detected in some" "testis cancer: 1.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SH-SY5Y: 356.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029430 Enhanced Supported "Nuclear speckles,Plasma membrane" NA NA "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane" "Nuclear speckles" "HPA029430: AB_10603785" "unprognostic (2.28e-1)" "unprognostic (3.45e-1)" "unprognostic (2.58e-2)" "unprognostic (2.36e-1)" "unprognostic (1.32e-1)" "unprognostic (1.12e-1)" "unprognostic (9.16e-3)" "unprognostic (1.97e-1)" "unprognostic (4.28e-2)" "unprognostic (7.20e-2)" "unprognostic (3.12e-1)" "unprognostic (1.01e-1)" "unprognostic (1.86e-4)" "unprognostic (2.65e-3)" "unprognostic (2.76e-1)" "unprognostic (1.53e-1)" "unprognostic (4.48e-1)" 0.3 39.3 4.4 5.1 2.0 0.0 0.1 6.3 1.0 1.0 0.3 8.1 1.5 0.5 0.0 0.1 0.0 0.3 0.4 0.7 2.3 0.0 0.0 0.2 0.3 3.1 6.4 0.1 0.2 0.0 1.1 0.1 10.0 0.2 4.0 53.5 0.1 0.0 0.1 0.7 3.0 3.7 0.3 0.1 2.8 1.0 9.2 65.8 0.2 0.0 0.8 0.2 0.7 1.0 0.1 0.3 0.7 0.6 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.0 1.5 0.0 8.8 0.0 0.0 0.3 1.4 0.5 0.4 0.1 0.0 0.1 4.0 0.0 0.3 0.0 0.0 0.0 0.0 22.6 0.2 0.0 0.0 0.3 7.1 0.0 1.6 0.1 0.2 0.4 0.3 0.1 0.0 0.4 67.7 356.1 0.3 0.1 0.1 0.5 0.4 0.0 0.0 0.1 1.7 0.1 0.4 0.2 0.7 0.1 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 2.0 6.3 1.0 0.7 2.3 3.1 6.4 10.0 0.3 9.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.8 0.0 0.0 0.0 164.7 0.0 0.0 0.2 1.9 0.0 3.7 0.1 1.2 0.4 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.2 1.7 0.4 3.6 0.0 0.0 0.0 3.5 0.0 0.2 0.0 0.0 0.0 3.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.1 0.1 0.3 2.1 0.0 0.0 0.0 0.0 2.6 0.1 0.1 CHTOP "C1orf77, DKFZP547E1010, FOP, SRAG" ENSG00000160679 "Chromatin target of PRMT1" Q9Y3Y2 1 153633982-153646306 "Plasma proteins, Predicted intracellular proteins" "mRNA transport, Transcription, Transcription regulation, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028647, HPA030540" Approved Enhanced "Nuclear speckles" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "HPA028647: AB_10602699, HPA030540: AB_2673516" "unprognostic (2.72e-1)" "unprognostic (2.41e-1)" "unprognostic (3.41e-2)" "unprognostic (6.77e-2)" "unprognostic (6.80e-2)" "unprognostic (3.08e-2)" "prognostic unfavorable (4.85e-4)" "unprognostic (8.65e-2)" "prognostic unfavorable (4.08e-4)" "unprognostic (9.16e-2)" "unprognostic (2.20e-1)" "unprognostic (7.30e-3)" "prognostic unfavorable (2.02e-4)" "unprognostic (1.58e-2)" "unprognostic (4.19e-2)" "unprognostic (2.70e-1)" "prognostic favorable (2.69e-4)" 42.4 44.8 48.1 36.5 54.1 62.5 44.2 54.7 56.0 52.5 48.3 44.2 30.3 45.2 36.2 50.3 47.5 21.9 63.3 47.8 51.1 66.5 54.8 39.3 46.6 51.9 50.7 55.2 63.4 35.9 48.7 33.4 52.2 48.4 32.7 59.9 44.4 29.6 124.4 52.6 46.8 30.5 50.0 65.4 47.9 37.6 49.6 65.7 55.8 68.4 44.4 45.1 47.9 63.5 74.3 63.9 106.2 65.0 45.2 33.1 84.3 51.2 47.0 71.3 61.2 71.6 72.9 83.5 75.6 48.0 46.6 66.8 103.4 74.7 46.9 97.8 95.7 65.5 102.2 60.0 56.1 101.8 78.8 38.5 84.8 69.0 97.5 59.2 57.7 89.4 82.1 62.2 54.1 94.3 109.8 102.6 123.6 106.9 79.1 67.5 65.0 92.5 69.8 100.5 64.3 74.5 54.6 77.8 91.6 69.9 83.7 138.6 50.0 47.7 70.4 60.7 83.8 86.2 77.8 95.5 50.1 81.9 56.8 84.9 42.9 40.9 46.0 44.8 46.2 46.2 45.3 45.3 54.4 43.3 45.2 41.0 30.8 35.1 43.0 41.7 51.9 46.4 48.1 54.1 54.7 56.0 47.8 51.1 51.9 50.7 52.2 50.0 49.6 63.5 46.4 32.1 37.3 32.3 50.1 63.0 103.6 59.7 37.5 40.8 45.6 33.5 74.1 57.2 43.5 53.3 33.3 91.7 47.7 49.2 50.9 69.5 34.9 50.6 42.6 54.2 60.3 81.9 16.1 64.8 121.9 47.1 42.3 63.4 46.3 59.7 43.9 41.2 69.7 43.7 17.6 56.4 42.7 48.9 38.2 18.0 44.7 40.9 35.6 14.0 69.3 44.0 52.5 16.6 40.1 61.3 58.1 42.2 48.2 101.8 48.4 49.0 33.2 57.5 19.7 34.9 59.7 125.2 115.2 46.5 61.7 128.6 45.7 57.9 52.3 110.2 CIR1 CIR ENSG00000138433 "Corepressor interacting with RBPJ, CIR1" Q86X95 2 174348022-174395712 "Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 187.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 187.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015784, HPA061442" Approved Supported "Nuclear speckles" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" "HPA015784: AB_1846782, HPA061442: AB_2732664" "unprognostic (3.17e-3)" "unprognostic (4.07e-2)" "unprognostic (1.65e-1)" "prognostic unfavorable (9.56e-4)" "unprognostic (2.40e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (2.52e-4)" "unprognostic (1.00e-2)" "unprognostic (4.39e-2)" "prognostic favorable (9.80e-4)" "unprognostic (1.27e-1)" "unprognostic (3.66e-2)" "prognostic unfavorable (1.04e-7)" "unprognostic (2.23e-1)" "unprognostic (1.48e-1)" "unprognostic (8.10e-3)" "prognostic favorable (2.04e-5)" 26.7 23.8 36.3 23.4 38.1 67.3 35.9 38.5 61.1 26.6 39.5 27.7 25.8 27.4 43.5 20.3 28.3 23.4 28.7 36.0 37.3 25.9 27.5 26.7 31.1 36.8 37.0 33.7 24.9 27.4 25.1 29.8 36.6 26.2 26.3 23.6 24.9 26.0 30.7 30.5 26.7 20.7 35.9 35.0 25.5 31.4 36.3 32.3 29.0 25.2 29.5 24.0 24.2 40.1 20.4 11.4 26.5 21.2 36.3 50.4 39.2 32.9 46.5 32.3 39.5 21.5 30.7 14.1 30.3 32.4 28.3 24.0 22.1 23.4 38.6 26.1 29.1 29.4 17.8 34.9 35.1 35.2 26.0 41.7 41.9 35.5 26.5 55.6 32.4 24.9 30.7 30.8 31.0 19.5 44.1 55.6 24.5 33.2 31.6 24.7 38.1 42.2 38.4 32.1 30.7 36.1 22.7 28.7 52.9 45.7 21.6 51.6 33.6 26.1 19.0 24.9 17.3 34.6 31.4 5.2 37.4 18.2 23.3 71.0 33.8 55.9 28.4 31.7 28.4 41.2 32.2 30.5 21.4 40.5 33.4 30.9 187.8 45.3 33.9 39.5 37.2 28.3 36.3 38.1 38.5 61.1 36.0 37.3 36.8 37.0 36.6 35.9 36.3 40.1 82.0 118.6 79.8 30.0 80.8 28.6 52.2 118.6 39.3 51.7 40.6 66.8 61.4 61.5 101.2 42.3 31.3 72.7 116.5 69.1 119.3 67.3 201.5 192.2 79.7 58.7 51.4 102.5 30.4 78.7 58.1 69.9 30.1 79.6 81.6 59.1 75.7 58.6 63.8 45.4 33.7 81.9 85.5 93.0 30.3 43.4 107.2 75.3 33.8 22.5 108.2 85.7 111.2 30.2 37.3 57.7 79.8 82.4 49.1 37.5 91.6 114.0 202.3 56.2 72.3 71.4 72.1 219.5 54.7 25.4 32.0 116.0 80.5 62.6 53.5 45.7 CLIC5 DFNB102 ENSG00000112782 "Chloride intracellular channel 5" Q9NZA1 6 45880827-46080348 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Hearing, Ion transport, Sensory transduction, Transport, Vision" "Chloride channel, Ion channel, Voltage-gated channel" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 102.7;skeletal muscle: 289.7;tongue: 98.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 509.6;Cardiomyocytes: 285.7;Distal enterocytes: 164.2;Late spermatids: 93.8;Proximal enterocytes: 126.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 11.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 5.1" "Lineage enriched" "Detected in single" 17 "T-cells: 5.1" "Cell line enhanced" "Detected in some" "CAPAN-2: 13.5;EFO-21: 9.2;HDLM-2: 4.7;REH: 11.9;U-266/70: 12.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074371 Supported "Nuclear speckles,Plasma membrane" NA NA 400000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Nuclear speckles" "HPA074371: " "unprognostic (4.95e-2)" "unprognostic (1.59e-2)" "unprognostic (8.84e-2)" "unprognostic (5.05e-2)" "unprognostic (2.44e-1)" "unprognostic (6.73e-2)" "unprognostic (3.37e-1)" "unprognostic (1.26e-1)" "unprognostic (1.79e-1)" "unprognostic (6.46e-2)" "unprognostic (5.50e-2)" "unprognostic (3.65e-1)" "unprognostic (6.77e-3)" "unprognostic (1.22e-1)" "unprognostic (1.99e-1)" "unprognostic (8.26e-2)" "unprognostic (1.01e-1)" 18.9 1.5 3.2 4.3 4.4 0.2 6.5 1.5 2.9 19.0 0.5 28.6 20.9 2.1 0.9 2.9 4.5 3.0 102.7 2.1 5.0 54.7 0.3 70.8 1.7 2.1 3.8 0.5 1.1 1.7 3.0 16.5 2.2 2.6 25.8 16.9 2.7 1.4 289.7 1.2 36.6 2.3 1.8 44.5 1.6 1.4 5.5 1.0 7.3 98.3 1.9 2.0 2.6 1.9 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 13.5 0.0 9.2 0.0 0.0 0.3 0.0 0.1 0.0 4.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.0 0.1 0.4 1.6 0.0 11.9 0.3 0.1 0.1 0.4 0.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.4 0.1 0.0 12.8 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 1.5 0.0 5.1 0.1 2.0 1.3 0.0 0.0 0.3 0.2 0.0 0.3 0.0 0.0 1.0 0.5 3.2 4.4 1.5 2.9 2.1 5.0 2.1 3.8 2.2 1.8 5.5 1.9 59.6 509.6 30.0 4.6 1.4 0.1 0.1 0.0 1.2 0.3 0.5 0.4 285.7 5.7 26.9 14.7 0.0 0.2 0.7 164.2 0.0 1.7 52.9 4.6 0.5 29.8 13.1 0.4 8.6 0.2 0.1 7.9 0.5 5.7 1.3 0.0 0.7 0.0 0.0 0.0 5.4 23.5 0.0 0.0 0.0 93.8 0.9 0.7 0.0 34.7 0.6 53.8 0.0 0.5 2.9 2.9 51.1 0.7 3.4 3.2 126.0 2.9 11.4 1.8 0.0 6.1 4.3 1.0 0.1 0.1 0.1 2.2 5.8 0.1 13.5 4.3 CMTR2 "AFT, FLJ11171, FTSJD1, MTr2" ENSG00000180917 "Cap methyltransferase 2" Q8IYT2 16 71281389-71289715 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA capping, mRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 95.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041700, HPA048265" Uncertain Approved "Nuclear speckles,Cell Junctions" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" "Cell Junctions" "Nuclear speckles" "HPA041700: AB_2677623, HPA048265: AB_2680334" "unprognostic (1.27e-1)" "unprognostic (2.49e-2)" "unprognostic (2.94e-3)" "unprognostic (1.43e-1)" "unprognostic (6.30e-2)" "unprognostic (3.82e-2)" "unprognostic (1.93e-3)" "unprognostic (2.86e-2)" "unprognostic (7.93e-2)" "unprognostic (3.41e-1)" "unprognostic (1.85e-2)" "unprognostic (7.39e-2)" "prognostic favorable (4.97e-5)" "unprognostic (9.55e-2)" "unprognostic (5.99e-2)" "unprognostic (1.54e-1)" "unprognostic (5.34e-2)" 6.7 8.8 4.0 10.3 4.6 7.2 15.9 4.6 4.2 7.6 8.0 10.1 14.9 8.5 12.2 14.3 9.0 9.4 7.0 3.2 4.7 12.5 14.3 11.4 14.4 5.1 4.4 11.2 8.1 10.7 7.8 10.6 4.8 10.8 10.4 7.3 13.3 8.0 5.7 10.3 14.2 9.0 5.2 13.6 10.0 13.8 4.9 10.7 14.1 5.7 17.9 9.7 7.6 6.6 17.8 11.6 23.2 19.5 18.9 15.3 10.6 14.9 18.2 17.4 18.4 10.6 26.5 10.0 18.4 13.7 18.9 19.4 11.1 14.2 24.9 10.5 7.9 22.3 13.1 8.3 20.3 16.8 37.7 12.7 24.7 15.4 17.9 12.8 18.5 22.2 11.6 6.6 31.1 15.9 18.8 23.1 11.0 14.2 6.7 28.5 10.2 24.5 16.3 19.5 12.0 12.8 15.1 12.2 15.4 10.3 18.0 10.4 18.7 21.1 15.1 15.5 11.4 13.3 17.6 21.3 14.7 14.6 16.8 22.6 9.6 9.2 10.8 10.3 13.2 13.1 10.6 11.7 13.7 12.0 11.4 11.1 0.7 16.6 6.9 3.9 9.8 11.4 4.0 4.6 4.6 4.2 3.2 4.7 5.1 4.4 4.8 5.2 4.9 6.6 11.4 3.2 11.8 13.7 28.1 14.1 14.5 10.7 15.9 20.3 23.9 13.7 8.6 20.0 9.4 16.5 31.3 24.2 30.2 25.8 7.9 12.2 95.6 12.6 15.1 14.6 18.6 17.0 9.9 9.7 12.7 11.5 15.8 11.5 8.2 26.1 18.9 32.7 16.1 15.2 10.3 20.5 18.3 18.0 11.4 30.9 16.8 13.6 1.8 21.5 17.8 12.1 51.5 17.6 21.5 12.9 15.2 12.4 17.9 13.5 46.3 17.7 6.5 25.5 6.6 11.1 10.1 26.1 13.8 22.0 24.3 26.4 20.0 21.8 17.9 18.2 CMYA5 "C5orf10, DKFZp451G223, SPRYD2, TRIM76" ENSG00000164309 "Cardiomyopathy associated 5" Q8N3K9 5 79689836-79800240 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "skeletal muscle: 623.5;tongue: 799.5" "Cell type enriched" "Detected in many" 15 "Cardiomyocytes: 3425.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 1.3;RT4: 1.5;THP-1: 5.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA074081, HPA077831" Enhanced Approved "Nuclear speckles,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 43: THP-1 - Innate immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nuclear speckles, Cytosol" "Vesicles, Plasma membrane" "HPA074081: , HPA077831: " "unprognostic (5.53e-2)" "unprognostic (9.91e-3)" "unprognostic (1.21e-2)" "unprognostic (1.49e-2)" "unprognostic (9.01e-4)" "unprognostic (7.00e-2)" "unprognostic (7.39e-2)" "unprognostic (1.20e-1)" "unprognostic (1.64e-1)" "unprognostic (1.75e-1)" "unprognostic (5.04e-1)" "unprognostic (1.93e-1)" "unprognostic (1.93e-2)" "unprognostic (6.30e-3)" "unprognostic (3.88e-2)" "unprognostic (7.69e-2)" "unprognostic (9.74e-2)" 0.9 0.1 1.4 0.2 1.4 0.0 3.9 1.2 2.1 1.7 3.1 1.3 0.1 5.9 4.6 6.6 2.1 0.9 155.8 0.6 0.6 2.5 1.2 0.5 0.0 1.6 2.0 14.6 0.3 3.6 2.0 1.1 1.1 6.1 0.2 1.7 6.1 2.1 623.5 2.2 0.4 4.6 1.1 0.0 0.6 0.5 1.7 0.9 2.3 799.5 0.1 2.1 1.2 0.8 0.0 0.0 0.0 0.1 0.5 0.4 0.6 0.2 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.0 1.0 5.4 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.4 1.2 2.1 0.6 0.6 1.6 2.0 1.1 1.1 1.7 0.8 2.7 9.6 2.8 69.5 0.4 1.3 17.9 2.9 4.6 2.0 24.4 46.6 3425.2 5.7 12.2 25.8 0.0 21.4 1.3 0.4 17.6 0.7 0.3 29.3 7.2 19.7 1.8 0.0 32.9 0.4 2.9 113.7 3.6 55.2 1.3 2.5 0.4 2.3 2.1 217.0 10.7 0.2 8.2 0.6 1.6 2.3 14.9 1.4 0.0 6.5 0.1 8.8 2.1 156.3 2.9 0.6 0.2 13.5 0.6 4.8 0.0 15.4 6.2 3.0 0.0 165.6 23.1 2.5 2.0 2.2 5.4 32.8 1.2 1.7 0.2 18.1 COG6 "COD2, KIAA1134" ENSG00000133103 "Component of oligomeric golgi complex 6" Q9Y2V7 13 39655627-39791665 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Congenital disorder of glycosylation, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 123.1;Inhibitory neurons: 99.9;Oligodendrocyte precursor cells: 82.9;Oligodendrocytes: 89.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040410, HPA040441" Uncertain Approved "Nuclear speckles,Golgi apparatus" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear speckles, Golgi apparatus" "HPA040410: AB_10793964, HPA040441: AB_10794030" "unprognostic (2.94e-2)" "unprognostic (1.65e-2)" "unprognostic (9.85e-2)" "unprognostic (1.05e-2)" "unprognostic (4.81e-2)" "unprognostic (4.99e-2)" "unprognostic (6.81e-2)" "unprognostic (9.59e-2)" "unprognostic (3.66e-2)" "unprognostic (1.14e-1)" "unprognostic (9.07e-2)" "unprognostic (1.62e-1)" "unprognostic (6.60e-3)" "prognostic favorable (2.81e-4)" "unprognostic (4.87e-2)" "unprognostic (2.14e-1)" "unprognostic (2.24e-1)" 8.7 10.5 2.1 7.9 3.8 2.1 9.7 5.3 5.8 12.0 5.0 9.3 10.5 9.2 4.4 10.6 9.9 10.5 15.8 5.5 2.6 9.8 8.9 6.8 8.3 2.1 2.3 14.2 19.0 18.3 13.3 13.7 3.2 13.0 8.4 7.2 13.0 8.8 6.4 10.1 9.7 7.7 1.7 8.0 12.5 16.4 2.1 8.8 14.0 8.5 7.7 10.2 6.4 6.1 10.8 7.0 10.8 7.7 21.0 26.5 20.6 17.0 24.1 14.2 17.4 8.6 16.8 18.2 9.6 24.7 16.7 13.5 11.5 12.9 15.1 21.5 16.1 17.7 7.0 12.5 12.0 17.9 18.1 11.2 15.9 8.9 10.0 17.8 13.9 16.5 7.5 6.8 23.1 11.0 13.4 16.5 10.6 30.2 8.9 12.8 29.3 8.8 10.0 13.6 6.3 8.2 15.4 12.8 13.0 14.8 14.9 11.2 20.7 7.9 9.3 17.6 8.5 5.3 5.5 13.6 23.4 9.5 23.6 3.0 3.2 4.0 3.8 5.0 6.6 4.7 4.9 5.3 4.5 4.4 4.1 5.4 0.7 7.1 3.1 2.5 6.4 4.2 2.1 3.8 5.3 5.8 5.5 2.6 2.1 2.3 3.2 1.7 2.1 6.1 8.7 19.2 7.8 46.0 12.6 9.7 5.9 9.5 8.0 15.2 11.0 8.4 22.0 2.8 10.2 12.9 10.4 15.6 9.5 9.9 5.9 7.7 23.4 13.9 14.8 8.5 9.1 9.5 123.1 10.0 29.6 12.3 10.7 13.0 10.1 9.7 12.1 9.6 8.6 5.0 99.9 19.8 8.2 6.7 3.9 12.6 13.4 7.6 1.8 37.5 5.9 15.5 7.2 82.9 89.4 8.7 10.8 12.8 17.7 5.0 10.2 12.4 13.2 12.5 6.6 12.2 9.7 39.0 27.4 11.9 13.4 16.0 10.3 12.6 10.3 5.7 COPS4 CSN4 ENSG00000138663 "COP9 signalosome subunit 4" Q9BT78 4 83034447-83075818 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036894, HPA042828" Approved Supported "Nuclear speckles" NA NA 100000 "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" "HPA036894: AB_10670929, HPA042828: AB_2678191" "unprognostic (1.82e-3)" "unprognostic (1.01e-2)" "prognostic favorable (4.14e-4)" "unprognostic (7.97e-3)" "unprognostic (1.39e-1)" "unprognostic (1.54e-1)" "unprognostic (1.73e-2)" "unprognostic (1.57e-1)" "unprognostic (8.96e-2)" "unprognostic (3.26e-1)" "unprognostic (3.10e-2)" "unprognostic (9.21e-2)" "prognostic favorable (5.21e-6)" "unprognostic (5.84e-2)" "unprognostic (3.07e-1)" "unprognostic (1.72e-1)" "unprognostic (2.80e-1)" 25.6 38.6 28.4 22.0 30.7 41.0 32.0 26.9 33.5 31.7 26.0 27.4 23.1 30.8 28.8 30.5 26.0 22.5 59.7 30.6 35.0 38.8 29.2 22.2 29.9 28.4 29.9 31.9 24.6 43.7 39.2 30.2 32.0 30.3 25.1 45.6 23.7 30.5 104.8 26.7 22.0 33.3 28.7 22.5 22.4 45.0 30.8 36.2 38.4 84.1 32.7 31.8 23.5 28.9 51.7 30.4 64.1 59.0 56.0 71.7 34.8 67.2 85.7 74.8 66.0 43.7 51.8 86.9 57.3 140.5 41.3 37.7 80.6 68.9 101.1 55.6 56.9 50.4 43.5 42.1 46.3 86.8 135.6 54.4 47.0 55.8 47.8 56.2 101.1 53.5 65.2 48.0 91.9 43.4 105.0 63.6 35.3 81.1 40.6 74.0 48.8 48.1 59.8 47.2 67.7 39.6 45.0 69.4 43.5 43.8 52.7 46.4 66.7 52.2 55.1 39.7 48.6 49.8 32.7 96.8 50.3 55.2 52.8 91.4 37.0 55.2 43.0 50.4 53.9 39.7 47.1 49.7 45.3 38.9 44.7 48.1 8.2 54.6 59.8 29.0 47.6 52.3 28.4 30.7 26.9 33.5 30.6 35.0 28.4 29.9 32.0 28.7 30.8 28.9 25.6 12.8 20.1 21.9 34.1 42.8 42.2 94.5 23.3 38.7 20.1 23.4 81.3 20.0 51.5 20.2 31.3 82.5 36.5 14.5 90.1 42.4 130.6 24.9 27.6 31.9 31.2 26.5 34.7 33.2 62.7 39.9 15.3 21.3 34.2 38.2 20.0 22.4 49.0 26.9 32.9 22.0 67.1 29.2 29.2 38.3 30.7 27.2 33.8 18.7 37.8 62.5 37.0 28.6 32.9 28.2 22.1 42.9 28.6 20.5 22.6 75.7 37.9 44.6 32.9 34.1 42.5 121.2 50.2 29.7 35.2 95.0 32.8 53.3 26.3 34.3 CPD GP180 ENSG00000108582 "Carboxypeptidase D" O75976 17 30378927-30469989 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 25.0" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052796, HPA055465" Approved Approved "Nucleoplasm,Nuclear membrane,Nuclear speckles" NA NA 1700000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 21: OE19 - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Nuclear speckles" "Nuclear membrane" "HPA052796: AB_2681953, HPA055465: AB_2682823" "unprognostic (1.05e-1)" "unprognostic (1.31e-1)" "unprognostic (3.05e-2)" "unprognostic (3.62e-2)" "unprognostic (6.13e-2)" "unprognostic (1.65e-1)" "unprognostic (7.97e-3)" "unprognostic (4.45e-2)" "unprognostic (2.07e-2)" "unprognostic (2.96e-1)" "unprognostic (1.62e-1)" "unprognostic (3.16e-1)" "unprognostic (1.58e-1)" "unprognostic (3.74e-2)" "unprognostic (7.25e-2)" "unprognostic (3.36e-1)" "unprognostic (1.08e-1)" 25.9 7.4 10.8 19.7 13.1 32.2 20.5 15.4 25.6 40.9 9.4 18.0 20.3 15.8 13.2 12.1 23.0 31.8 9.1 11.8 13.0 19.7 25.4 18.2 7.9 19.5 13.3 7.8 15.7 28.5 6.1 30.3 17.8 16.8 20.1 14.9 44.8 11.2 8.1 8.2 19.8 23.3 18.3 9.3 37.3 41.3 13.5 8.3 57.6 14.0 9.9 18.3 7.1 28.0 39.4 58.9 50.0 51.6 51.0 95.9 18.0 53.1 77.2 36.0 43.9 69.6 24.9 5.1 65.8 61.3 45.6 27.6 32.7 67.1 60.3 18.7 46.7 11.2 32.5 43.2 61.8 73.8 28.3 172.3 29.4 46.2 44.3 59.7 74.3 16.5 22.1 56.1 29.2 7.7 23.9 20.3 14.1 89.8 13.4 22.6 57.8 15.3 67.3 44.2 12.5 31.5 63.4 54.0 27.6 58.0 51.2 50.4 89.2 35.7 23.3 56.2 51.3 22.5 50.0 16.1 45.6 47.2 30.9 4.5 7.7 8.4 4.1 3.6 4.5 0.2 2.1 3.5 4.4 0.4 1.6 2.0 25.0 2.7 3.2 0.5 1.5 3.6 10.8 13.1 15.4 25.6 11.8 13.0 19.5 13.3 17.8 18.3 13.5 28.0 124.4 32.1 23.9 28.4 7.5 22.0 34.2 99.2 21.6 30.8 34.9 18.8 13.7 155.8 129.5 29.5 45.9 24.8 35.9 37.8 1.9 32.4 96.1 21.9 24.9 51.9 32.3 15.6 62.9 24.8 11.1 25.6 72.4 35.2 24.1 21.6 56.0 93.9 15.9 47.1 57.1 69.0 85.5 31.2 20.4 56.0 16.8 33.7 30.2 90.9 32.9 13.4 29.9 45.8 164.5 32.8 26.4 16.1 38.1 58.5 50.1 18.5 84.2 33.8 0.0 21.3 23.4 31.0 21.0 21.1 18.6 24.1 35.6 14.2 34.4 50.7 CPSF6 "CFIM, CFIM68, CFIM72, HPBRII-4, HPBRII-7" ENSG00000111605 "Cleavage and polyadenylation specific factor 6" Q16630 12 69239569-69274358 "Plasma proteins, Predicted intracellular proteins" "mRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039973 Supported Enhanced "Nucleoplasm,Nuclear speckles" No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nuclear speckles" "HPA039973: AB_10795242" "unprognostic (1.50e-1)" "unprognostic (3.33e-2)" "unprognostic (4.37e-3)" "unprognostic (5.47e-2)" "unprognostic (4.24e-2)" "unprognostic (7.74e-2)" "prognostic unfavorable (1.91e-6)" "unprognostic (6.82e-2)" "unprognostic (2.91e-3)" "unprognostic (8.57e-2)" "unprognostic (1.52e-1)" "unprognostic (2.53e-2)" "prognostic unfavorable (2.11e-4)" "unprognostic (2.20e-1)" "unprognostic (7.63e-2)" "unprognostic (2.05e-1)" "unprognostic (7.41e-2)" 23.8 26.3 14.4 35.8 13.9 71.9 23.8 30.5 16.8 27.5 1.8 24.0 26.2 28.4 38.6 27.8 25.3 18.3 21.5 14.5 18.0 20.8 20.6 22.5 46.9 6.1 5.6 40.5 23.9 28.3 26.5 25.0 8.4 23.1 24.8 43.5 26.0 20.2 27.9 24.6 25.4 23.7 8.2 27.1 26.6 22.3 12.6 43.6 26.6 17.0 40.8 25.6 25.2 12.3 97.5 80.3 115.7 81.7 43.8 49.7 87.1 62.7 74.1 87.3 82.0 83.8 64.8 153.6 62.6 63.9 48.5 89.2 114.5 73.7 92.3 101.4 78.1 124.3 85.7 97.1 65.4 170.1 87.1 60.0 57.2 70.4 28.7 58.2 68.3 90.6 130.1 159.6 73.3 112.9 159.9 110.3 112.3 80.4 67.8 159.9 91.6 108.2 68.9 113.4 97.0 85.4 83.7 77.7 88.9 68.8 93.2 118.5 79.1 65.4 80.0 62.6 104.5 101.9 88.5 190.9 53.1 97.5 85.9 44.3 26.0 29.9 27.9 32.6 29.5 32.8 30.8 29.1 39.0 28.9 23.4 28.2 7.7 30.2 28.7 27.8 47.2 19.7 14.4 13.9 30.5 16.8 14.5 18.0 6.1 5.6 8.4 8.2 12.6 12.3 29.1 12.8 24.9 53.2 49.9 76.0 46.7 55.7 43.3 56.5 30.0 24.5 31.7 30.0 39.9 18.4 37.5 64.6 51.1 22.5 37.2 59.6 18.7 35.6 40.2 35.0 52.5 47.1 97.6 56.8 85.7 36.6 33.6 37.9 34.9 54.0 23.6 23.0 39.5 89.2 115.4 32.6 75.3 29.3 39.7 19.8 56.8 37.1 24.9 53.4 53.5 37.8 45.3 137.2 126.0 61.1 23.3 53.0 56.3 37.4 25.4 26.6 28.0 45.8 39.5 37.4 56.0 68.1 69.4 43.9 59.1 51.2 38.5 54.1 36.2 51.5 CRIP1 CRIP ENSG00000213145 "Cysteine rich protein 1" P50238 14 105486317-105488947 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 980.8;Endometrial ciliated cells: 1761.1;Proximal enterocytes: 2548.8;Respiratory ciliated cells: 1702.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 699.8;CAPAN-2: 415.5;HaCaT: 464.1;HDLM-2: 329.5;OE19: 1305.8;T-47d: 586.0" HPA042462 Approved Approved "Nuclear speckles,Plasma membrane,Centrosome,Cytosol" NA NA 29000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 31: Skin - Epidermis development" "Cluster 21: OE19 - Mitochondria" "Cluster 11: Alveolar cells - Smell perception" "Nuclear speckles, Cytosol" "Plasma membrane, Centrosome" "HPA042462: AB_10794277" "unprognostic (2.97e-3)" "unprognostic (1.27e-3)" "unprognostic (1.34e-2)" "unprognostic (1.17e-2)" "unprognostic (2.39e-1)" "unprognostic (2.93e-3)" "unprognostic (4.33e-1)" "unprognostic (3.33e-1)" "unprognostic (3.20e-2)" "unprognostic (2.60e-2)" "unprognostic (2.87e-1)" "unprognostic (9.16e-2)" "unprognostic (3.26e-3)" "unprognostic (5.10e-2)" "unprognostic (2.66e-1)" "unprognostic (7.51e-3)" "unprognostic (2.14e-1)" 265.2 21.7 19.2 61.1 19.7 29.4 180.8 20.0 36.4 147.4 20.3 133.9 121.7 108.0 206.6 118.7 118.2 28.1 262.6 18.5 20.3 109.7 17.8 254.6 83.9 26.9 29.1 49.8 18.3 21.2 41.5 28.3 24.6 49.6 55.4 0.2 135.7 87.9 44.7 301.1 312.5 42.4 24.7 94.5 94.2 14.3 21.0 79.6 182.1 50.2 135.7 113.7 98.9 20.3 0.0 699.8 4.8 0.6 12.1 8.3 66.8 1.3 0.4 9.0 0.1 21.0 415.5 228.0 2.4 191.0 2.6 464.1 0.1 0.0 0.0 329.5 0.0 17.7 294.7 116.3 1.8 0.1 0.2 3.8 0.0 23.1 0.0 0.9 0.5 64.6 0.5 0.9 0.0 3.7 8.1 1.6 7.4 1305.8 36.4 181.3 0.0 45.5 0.0 0.0 18.5 1.3 2.6 1.2 0.0 0.5 586.0 106.4 1.5 0.4 0.4 5.5 0.0 0.3 0.2 17.9 0.0 0.0 0.6 121.8 218.6 313.1 209.2 214.4 135.1 697.0 442.0 222.1 442.9 384.2 85.4 100.2 13.9 323.5 283.9 291.3 694.8 465.6 19.2 19.7 20.0 36.4 18.5 20.3 26.9 29.1 24.6 24.7 21.0 20.3 50.2 980.8 256.2 0.3 350.7 186.5 1.2 79.5 67.2 0.0 88.1 18.3 1.0 2.8 501.3 51.5 0.0 2.1 287.8 360.4 1.9 20.5 3.6 1761.1 124.5 86.4 76.5 27.3 0.0 3.1 4.3 313.3 210.0 491.9 521.5 0.1 24.7 1.3 52.2 0.0 0.0 243.1 30.5 168.0 577.3 26.2 25.1 523.7 370.0 1.9 461.4 0.2 83.4 0.0 0.1 34.2 659.2 9.4 584.3 0.7 2548.8 2.5 1702.1 0.0 223.5 8.2 448.0 1.0 11.4 29.4 251.6 1.5 524.7 0.1 190.7 3.0 CRIP3 "bA480N24.2, TLP, TLP-A" ENSG00000146215 "Cysteine rich protein 3" Q6Q6R5 6 43299710-43308826 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 24.3;testis: 25.7" "Cell type enhanced" "Detected in some" "Astrocytes: 9.4;Distal tubular cells: 9.8;Granulosa cells: 12.5;Late spermatids: 7.9;Oligodendrocyte precursor cells: 6.6" "Cancer enhanced" "Detected in some" "liver cancer: 3.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 16 "myeloid DC: 44.6" "Lineage enriched" "Detected in many" 16 "dendritic cells: 44.6" "Cell line enhanced" "Detected in some" "HAP1: 2.8;HEK 293: 3.3;HeLa: 3.5;Hep G2: 6.5;NTERA-2: 5.7;RPMI-8226: 4.6;THP-1: 2.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036198 Uncertain Approved "Nuclear speckles" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 40: Granulosa cells - Unknown function" "Nuclear speckles" "HPA036198: AB_10670791" "unprognostic (8.35e-3)" "unprognostic (4.14e-3)" "unprognostic (6.37e-2)" "unprognostic (5.34e-3)" "unprognostic (1.71e-1)" "unprognostic (1.07e-2)" "unprognostic (1.18e-1)" "unprognostic (2.30e-2)" "unprognostic (4.34e-2)" "unprognostic (1.46e-2)" "unprognostic (8.49e-4)" "unprognostic (1.86e-2)" "unprognostic (7.30e-3)" "unprognostic (5.02e-2)" "unprognostic (4.89e-2)" "unprognostic (4.46e-2)" "unprognostic (2.80e-4)" 0.8 0.6 10.1 1.7 10.2 2.6 0.9 11.3 16.5 2.4 8.1 1.1 2.0 1.3 1.6 0.7 2.0 0.6 24.3 10.1 10.4 5.3 10.4 0.6 5.4 9.4 9.4 2.1 1.6 2.1 2.3 0.2 9.4 5.7 0.4 2.5 0.8 8.0 0.4 1.8 3.5 0.6 9.0 7.9 0.8 25.7 10.0 1.6 2.0 0.0 5.9 1.1 1.4 10.4 0.0 0.8 0.2 0.1 0.2 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.2 0.0 0.1 0.6 2.8 0.1 0.0 0.0 3.3 0.0 3.5 6.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.7 0.0 0.0 0.0 0.0 4.6 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.4 0.6 2.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 2.7 0.9 0.0 1.7 0.0 2.3 0.0 0.0 44.6 2.6 0.0 0.0 0.8 0.3 2.3 0.4 0.0 1.8 10.1 10.2 11.3 16.5 10.1 10.4 9.4 9.4 9.4 9.0 10.0 10.4 0.2 0.0 0.0 9.4 2.8 0.6 0.3 0.0 0.0 0.9 0.1 0.8 3.2 5.7 0.1 0.0 0.0 0.0 0.1 0.3 9.8 1.1 3.9 1.1 0.2 0.2 0.0 0.8 4.7 0.2 0.0 0.2 0.0 0.1 0.0 12.5 0.0 2.9 0.2 0.0 3.5 0.1 0.0 0.9 3.4 7.9 1.2 0.7 0.0 1.0 1.4 0.5 1.0 6.6 3.4 0.3 0.1 0.0 0.1 0.1 0.7 4.5 0.3 0.8 0.0 0.3 0.4 5.3 1.6 0.0 0.0 0.0 0.3 1.0 0.4 0.1 CRY2 ENSG00000121671 "Cryptochrome circadian regulator 2" Q49AN0 11 45847118-45883248 "Predicted intracellular proteins" "Biological rhythms, Sensory transduction, Transcription, Transcription regulation" "Photoreceptor protein, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Bipolar cells: 141.9;Horizontal cells: 101.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037577 Supported Supported "Nuclear speckles,Cytosol" "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "Nuclear speckles" Cytosol "HPA037577: AB_10672497" "unprognostic (1.67e-1)" "unprognostic (9.35e-2)" "prognostic unfavorable (1.67e-4)" "unprognostic (1.31e-2)" "unprognostic (9.16e-2)" "unprognostic (3.09e-2)" "prognostic favorable (6.82e-5)" "unprognostic (1.48e-3)" "unprognostic (1.67e-1)" "unprognostic (5.07e-2)" "prognostic favorable (4.39e-4)" "unprognostic (1.01e-1)" "prognostic favorable (6.44e-15)" "unprognostic (8.13e-3)" "unprognostic (1.89e-1)" "unprognostic (4.24e-2)" "unprognostic (2.24e-1)" 31.8 22.3 33.3 8.9 35.3 29.4 27.1 36.4 36.9 24.4 22.8 26.5 10.8 23.3 16.9 15.9 29.1 17.4 60.0 36.6 29.3 22.5 62.7 22.9 10.4 27.4 31.5 38.7 34.7 22.4 30.8 13.5 28.5 25.3 9.9 52.8 21.7 22.1 96.7 50.4 16.7 17.1 28.8 14.0 24.6 34.4 35.2 12.6 34.0 64.8 10.3 26.0 18.4 31.4 1.4 4.2 6.3 7.5 16.7 8.4 13.8 5.0 8.9 6.2 4.5 6.8 3.3 9.8 3.8 10.5 5.9 8.5 6.0 5.2 4.3 9.8 5.5 6.4 8.2 9.4 6.4 8.0 8.5 9.9 7.5 4.8 7.6 7.0 4.4 7.5 12.7 16.2 5.6 5.3 6.8 9.4 17.1 17.8 5.0 11.5 9.1 4.6 4.5 7.8 10.1 3.8 8.3 7.5 4.5 8.0 10.0 5.5 5.5 8.7 5.3 13.5 3.6 15.0 10.8 7.9 5.3 3.5 5.3 4.1 3.5 5.4 5.7 4.8 4.7 5.0 5.5 6.1 3.6 4.6 6.6 6.9 1.8 7.5 8.0 2.6 4.9 5.3 33.3 35.3 36.4 36.9 36.6 29.3 27.4 31.5 28.5 28.8 35.2 31.4 11.7 12.8 18.2 48.0 12.6 17.0 9.7 5.1 8.0 141.9 10.6 8.6 34.7 14.3 11.6 7.3 27.1 8.0 10.0 17.2 29.4 5.4 24.2 28.1 7.5 9.2 7.1 3.0 30.3 4.7 5.6 19.8 12.8 15.4 14.7 10.8 8.6 47.3 3.6 101.0 26.0 7.4 6.1 8.5 12.5 8.7 31.4 7.2 16.0 10.3 6.2 34.4 10.3 13.0 13.6 6.0 6.0 39.9 8.5 11.6 10.5 11.6 23.8 27.5 19.7 14.5 14.6 29.1 15.0 4.4 17.5 9.3 9.1 8.4 6.0 9.8 CSRNP2 "C12ORF2, C12orf22, FAM130A1, PPP1R72, TAIP-12" ENSG00000110925 "Cysteine and serine rich nuclear protein 2" Q9H175 12 51061205-51083664 "Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 63.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018503, HPA019914" Approved Approved "Nuclear speckles" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 58: Brain - Synaptic function" "Cluster 12: NES - Nervous system development" "Cluster 7: Non-specific - Mitochondria" "Nuclear speckles" "HPA018503: AB_1845535, HPA019914: AB_2670315" "unprognostic (8.67e-3)" "unprognostic (1.00e-1)" "unprognostic (2.64e-1)" "unprognostic (1.97e-1)" "unprognostic (1.83e-1)" "unprognostic (9.07e-2)" "prognostic unfavorable (1.08e-4)" "unprognostic (1.38e-1)" "unprognostic (1.20e-1)" "unprognostic (2.41e-2)" "unprognostic (1.14e-1)" "unprognostic (5.10e-2)" "prognostic unfavorable (6.51e-4)" "unprognostic (1.10e-1)" "unprognostic (8.98e-2)" "unprognostic (1.74e-2)" "prognostic favorable (2.78e-4)" 12.2 10.4 19.1 7.4 19.3 3.3 11.1 15.5 21.9 13.4 13.3 11.9 6.7 13.7 11.9 7.7 11.2 11.6 12.7 19.3 19.7 12.2 6.8 10.8 8.3 14.1 15.4 12.4 9.3 11.8 17.6 11.4 14.2 11.6 7.0 20.5 9.9 10.5 16.8 9.5 8.8 14.6 12.0 10.0 10.0 26.2 19.2 13.9 11.4 14.7 7.0 12.3 9.7 16.5 9.0 10.2 30.2 27.1 22.8 16.0 31.5 17.3 19.9 23.8 16.3 19.6 6.4 7.5 16.2 18.7 16.2 10.8 14.9 9.5 18.8 15.4 10.4 8.9 12.1 6.1 24.7 6.2 12.8 19.6 26.4 27.6 15.6 25.9 23.6 34.0 12.5 13.1 27.8 15.6 21.3 8.6 24.8 4.2 14.3 12.5 19.1 6.0 13.6 11.6 21.2 25.1 25.1 20.0 25.9 21.2 12.7 17.2 21.4 23.6 12.4 15.8 11.9 13.5 16.0 6.9 14.5 8.1 7.7 0.0 0.3 1.0 0.7 0.0 0.2 0.4 0.7 0.4 0.4 0.2 0.7 1.0 1.0 2.2 0.2 0.1 0.5 0.2 19.1 19.3 15.5 21.9 19.3 19.7 14.1 15.4 14.2 12.0 19.2 16.5 17.8 3.2 6.8 13.1 9.4 17.8 11.4 7.1 8.0 6.8 14.1 20.2 19.5 5.7 5.4 5.5 25.0 6.6 13.8 15.4 3.9 6.9 23.5 10.3 14.4 12.7 8.3 4.0 39.9 5.0 9.2 15.6 63.2 10.0 11.4 13.1 13.6 2.6 6.5 6.7 32.3 10.8 8.2 4.4 14.8 14.8 6.2 9.7 16.0 11.2 4.2 5.4 5.2 23.6 20.7 8.0 7.5 7.9 10.8 10.0 8.6 4.2 7.4 7.6 0.0 20.2 17.3 28.6 13.8 6.8 16.1 15.1 12.5 5.9 5.7 6.6 CWC15 "AD002, C11orf5, Cwf15, HSPC148" ENSG00000150316 "CWC15 spliceosome associated protein homolog" Q9P013 11 94962620-94973586 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 883.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039878 Supported Approved "Nuclear speckles,Mitochondria" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 29: Early spermatids - Spermatogenesis" "Nuclear speckles, Mitochondria" "HPA039878: AB_2676722" "unprognostic (1.97e-1)" "unprognostic (5.51e-2)" "unprognostic (1.66e-2)" "unprognostic (8.64e-2)" "unprognostic (3.81e-1)" "unprognostic (6.85e-2)" "unprognostic (1.29e-1)" "unprognostic (1.52e-1)" "unprognostic (4.84e-3)" "prognostic favorable (9.75e-4)" "unprognostic (4.69e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (1.91e-5)" "unprognostic (1.44e-1)" "unprognostic (1.34e-1)" "prognostic favorable (7.17e-4)" "unprognostic (5.23e-2)" 23.1 21.8 37.3 14.2 37.5 32.3 30.5 38.5 46.3 22.5 33.9 20.4 16.0 20.8 34.1 23.6 21.3 13.9 35.0 37.1 39.1 31.2 37.6 17.3 25.1 38.3 39.8 27.0 22.4 25.9 15.7 25.6 38.5 19.9 19.4 25.2 27.0 19.7 68.7 18.1 18.3 17.4 38.6 18.9 21.7 40.0 38.0 30.8 25.1 60.1 24.4 22.0 20.7 39.4 27.1 16.5 63.3 32.3 54.4 50.1 33.0 40.1 52.4 59.9 51.0 80.6 62.4 40.3 76.2 51.1 41.2 28.9 33.8 47.3 66.3 50.7 30.5 51.3 20.5 40.0 45.3 65.9 31.8 47.9 54.1 36.7 54.0 50.2 59.5 44.3 58.2 37.2 56.1 29.4 65.2 87.6 32.0 66.6 42.9 43.7 38.2 44.2 61.1 30.2 35.2 28.8 42.0 44.7 35.9 53.3 72.1 50.8 35.8 44.4 35.2 60.7 41.0 16.9 41.2 57.4 25.5 73.4 44.8 45.9 22.6 33.9 23.6 28.1 32.3 28.7 31.3 29.0 29.6 25.2 29.7 30.7 27.4 26.8 35.9 28.7 34.4 23.7 37.3 37.5 38.5 46.3 37.1 39.1 38.3 39.8 38.5 38.6 38.0 39.4 67.1 73.7 63.9 12.4 69.3 59.3 84.6 150.1 54.7 59.3 56.1 80.0 170.3 92.9 112.2 51.5 14.6 146.7 75.5 62.4 221.1 122.2 883.6 57.7 60.9 74.3 28.4 96.2 15.4 144.0 126.3 80.0 42.8 57.9 104.4 68.6 96.0 121.3 128.7 40.4 17.0 68.3 83.4 69.5 62.4 203.6 112.8 68.8 71.2 14.0 109.1 142.6 104.0 13.0 21.5 125.7 85.4 92.9 59.2 90.9 99.0 245.9 89.1 59.1 138.1 72.5 98.8 267.7 196.2 80.2 63.9 119.3 71.3 69.9 65.2 70.9 CWC22 "EIF4GL, fSAPb, KIAA1604, NCM" ENSG00000163510 "CWC22 spliceosome associated protein homolog" Q9HCG8 2 179944876-180007297 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036748 Approved Supported "Nuclear speckles,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 50: Fibroblasts - ECM organization" "Nuclear speckles" Cytosol "HPA036748: AB_10669913" "unprognostic (1.90e-1)" "unprognostic (7.10e-2)" "unprognostic (7.30e-2)" "unprognostic (6.14e-2)" "unprognostic (4.96e-2)" "unprognostic (4.33e-2)" "prognostic unfavorable (7.42e-4)" "unprognostic (3.15e-1)" "unprognostic (1.31e-2)" "unprognostic (3.30e-2)" "unprognostic (3.84e-2)" "unprognostic (4.80e-2)" "prognostic unfavorable (7.76e-5)" "unprognostic (1.74e-1)" "unprognostic (3.03e-2)" "unprognostic (1.41e-1)" "unprognostic (9.44e-3)" 12.7 10.2 7.1 13.1 7.8 16.0 15.0 13.5 10.1 14.1 7.1 11.9 10.1 16.9 10.4 12.5 12.0 12.1 10.1 7.6 7.2 13.4 16.8 11.5 18.5 6.4 6.9 19.3 9.2 13.5 8.2 14.5 7.0 12.5 11.8 12.4 10.2 10.9 13.6 11.0 10.4 13.9 7.1 14.7 11.0 9.0 7.0 21.8 16.0 14.5 18.2 14.1 12.1 8.9 19.1 11.2 31.6 21.1 22.7 26.7 24.1 24.5 28.7 29.4 28.7 25.9 23.1 36.7 21.6 17.9 25.6 20.5 30.4 23.1 44.2 33.0 26.2 49.1 15.1 35.4 22.0 69.6 26.2 17.5 27.1 37.4 49.8 19.3 22.3 25.2 54.6 21.9 19.7 18.9 36.5 34.7 48.8 22.5 18.3 32.8 38.9 27.7 20.2 23.5 21.6 28.8 20.3 15.9 28.5 33.8 11.8 42.2 19.0 25.1 21.2 16.8 25.7 19.2 21.5 44.3 22.6 27.2 26.1 49.7 13.3 31.4 16.1 16.7 16.3 17.4 17.3 19.5 13.9 14.5 21.1 16.7 22.0 16.0 13.3 8.6 16.5 11.5 7.1 7.8 13.5 10.1 7.6 7.2 6.4 6.9 7.0 7.1 7.0 8.9 38.0 19.2 33.8 20.5 38.0 19.1 29.2 16.9 22.2 19.5 12.9 19.8 26.6 22.8 27.0 11.0 25.0 18.3 36.5 11.8 9.8 23.4 1.6 24.2 31.9 27.2 15.6 14.9 35.8 19.1 17.5 32.5 19.9 25.1 27.3 24.7 16.8 12.8 13.7 13.5 28.4 16.4 14.2 20.6 12.1 2.4 23.3 24.2 3.6 15.0 31.6 17.3 30.9 35.2 35.1 18.7 17.6 18.4 20.8 16.8 15.7 20.3 34.4 19.1 46.0 40.3 25.1 22.8 21.3 14.1 18.6 24.8 32.5 18.6 15.6 19.5 CWC25 "CCDC49, FLJ20291" ENSG00000273559 "CWC25 spliceosome associated protein homolog" Q9NXE8 17 38800441-38825355 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 62.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 28.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB014874, HPA062997" Supported Enhanced "Nuclear speckles" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "CAB014874: , HPA062997: AB_2684917" "unprognostic (2.21e-1)" "unprognostic (4.30e-2)" "unprognostic (1.84e-1)" "unprognostic (1.37e-1)" "unprognostic (4.75e-2)" "unprognostic (3.69e-2)" "unprognostic (1.01e-2)" "unprognostic (3.24e-2)" "unprognostic (3.43e-3)" "unprognostic (8.79e-3)" "unprognostic (4.17e-3)" "unprognostic (4.98e-2)" "unprognostic (1.32e-1)" "unprognostic (2.25e-2)" "unprognostic (2.69e-2)" "unprognostic (1.35e-1)" "unprognostic (8.68e-3)" 13.3 12.6 7.9 9.9 8.9 62.2 12.3 8.5 9.7 11.6 8.8 11.1 10.3 10.3 5.4 12.5 11.9 7.6 9.0 8.2 8.5 11.6 16.2 13.0 12.6 8.7 8.5 11.2 12.6 7.2 11.0 6.7 8.5 11.7 6.1 8.6 10.9 4.5 12.7 17.4 13.1 6.8 8.0 16.8 11.6 18.4 8.5 14.2 11.3 7.1 9.0 10.9 11.5 9.4 11.2 13.1 8.2 14.1 10.9 7.1 8.3 11.5 7.9 12.0 11.0 8.4 11.7 12.7 7.8 9.2 9.2 25.3 8.2 7.7 14.5 12.0 8.7 9.9 14.9 10.4 10.8 25.2 15.6 8.4 12.3 11.8 9.7 12.7 9.8 13.5 15.5 15.0 10.2 6.2 26.4 25.6 8.5 8.2 6.4 20.0 12.1 11.4 12.0 10.7 9.3 8.2 10.7 7.6 13.8 12.2 12.0 19.8 10.2 10.8 9.9 14.3 17.9 11.9 9.3 18.8 11.4 12.1 10.9 18.0 4.1 10.6 4.6 3.9 4.0 4.5 4.3 4.8 3.5 6.0 4.9 3.7 28.7 5.9 8.1 1.7 2.9 3.0 7.9 8.9 8.5 9.7 8.2 8.5 8.7 8.5 8.5 8.0 8.5 9.4 50.7 57.7 69.5 10.4 54.2 63.9 61.2 45.9 39.9 37.2 40.8 31.2 18.3 21.5 46.3 23.9 83.4 35.1 60.6 56.6 29.4 27.5 118.4 63.8 51.7 45.3 41.8 34.5 10.0 23.6 35.2 43.8 52.0 100.2 58.9 23.8 37.9 27.2 28.6 26.9 7.9 51.9 26.4 27.0 37.9 31.9 37.3 38.2 26.6 5.6 38.7 30.1 41.2 5.5 8.1 29.3 70.9 34.6 43.2 51.4 61.5 27.2 41.9 43.4 39.5 57.0 45.7 93.9 33.6 30.5 76.7 79.1 54.6 28.8 32.6 72.4 CWF19L2 FLJ32343 ENSG00000152404 "CWF19 like cell cycle control factor 2" Q2TBE0 11 107326345-107457844 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038166 Uncertain Approved "Nuclear speckles,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" Cytosol "HPA038166: AB_10669518" "unprognostic (1.38e-1)" "unprognostic (9.41e-2)" "unprognostic (1.37e-1)" "unprognostic (7.35e-2)" "unprognostic (7.17e-2)" "unprognostic (6.42e-2)" "unprognostic (8.78e-2)" "unprognostic (1.63e-1)" "unprognostic (4.19e-2)" "unprognostic (1.46e-1)" "unprognostic (1.06e-2)" "unprognostic (1.04e-1)" "unprognostic (1.40e-2)" "unprognostic (4.48e-2)" "unprognostic (1.26e-1)" "unprognostic (4.74e-2)" "unprognostic (1.76e-2)" 8.8 5.8 15.4 6.2 16.6 8.2 11.3 20.3 30.9 8.8 16.8 7.3 5.0 10.9 8.2 6.4 7.5 6.0 5.4 14.7 16.7 11.2 8.5 7.1 10.4 16.1 15.9 14.2 5.9 7.8 4.7 8.4 16.2 8.3 6.2 8.6 6.2 8.5 7.0 7.3 5.5 6.9 15.8 9.8 6.7 5.9 16.1 11.8 9.7 8.4 11.0 6.9 6.7 17.7 7.4 5.9 12.5 6.0 10.2 11.5 9.4 9.5 8.8 7.3 9.7 13.9 17.0 12.8 17.7 6.7 9.3 17.6 14.0 7.3 12.7 14.4 7.8 14.2 6.6 9.1 6.6 16.9 11.5 5.9 12.6 8.5 12.7 8.4 10.0 7.6 21.9 7.2 10.7 5.5 13.1 15.3 11.9 12.2 8.3 11.3 11.9 17.3 8.6 9.0 7.2 6.0 13.9 10.3 5.4 10.5 13.8 8.0 9.1 12.1 9.7 6.4 8.6 3.8 7.5 12.3 3.5 16.4 11.3 45.6 10.1 19.3 14.2 9.3 15.7 29.4 16.5 14.4 4.5 27.6 19.9 15.3 19.4 17.4 10.4 19.2 15.7 4.3 15.4 16.6 20.3 30.9 14.7 16.7 16.1 15.9 16.2 15.8 16.1 17.7 56.2 38.5 53.2 38.5 66.1 17.8 16.1 19.1 18.2 97.2 24.2 21.0 28.9 57.2 33.2 82.8 95.9 24.0 57.9 18.3 33.2 22.1 3.1 31.8 39.8 40.8 13.1 23.8 42.3 18.4 22.8 29.3 17.3 34.0 46.2 35.2 51.4 56.1 15.8 69.0 37.4 27.0 14.2 33.7 15.4 9.5 54.3 24.5 14.2 43.1 32.7 47.5 69.0 42.3 68.1 16.3 31.6 63.9 36.1 6.7 25.6 60.5 18.3 131.8 39.5 41.1 30.8 48.0 47.2 9.1 13.4 17.0 55.3 21.4 21.3 7.8 CYGB "HGB, STAP" ENSG00000161544 Cytoglobin Q8WWM9 17 76527356-76551175 "Predicted intracellular proteins, Transporters" "Oxygen transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 104.4" "Cell type enhanced" "Detected in many" "Adipocytes: 94.3;Fibroblasts: 87.6;Leydig cells: 95.7;Melanocytes: 78.2;Sertoli cells: 92.1;Smooth muscle cells: 95.6" "Cancer enhanced" "Detected in all" "melanoma: 34.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 2.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 79.6;Hep G2: 61.7;HHSteC: 120.7;HSkMC: 95.4;SH-SY5Y: 129.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017757, HPA061642" Approved Approved Supported "Nuclear speckles,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Nuclear speckles" Cytosol "HPA017757: AB_1847410, HPA061642: AB_2684573" "unprognostic (6.96e-2)" "unprognostic (1.39e-1)" "unprognostic (3.97e-2)" "prognostic favorable (2.55e-5)" "prognostic unfavorable (1.85e-4)" "unprognostic (3.36e-2)" "unprognostic (3.31e-3)" "unprognostic (2.01e-1)" "unprognostic (7.83e-2)" "unprognostic (1.42e-1)" "unprognostic (1.08e-2)" "unprognostic (4.14e-2)" "prognostic unfavorable (2.13e-4)" "unprognostic (3.34e-2)" "unprognostic (1.11e-2)" "unprognostic (2.49e-2)" "unprognostic (7.76e-2)" 79.6 20.8 10.1 12.0 10.7 1.7 55.1 20.6 13.6 27.7 14.1 27.1 21.1 19.6 4.6 12.8 20.4 13.2 104.4 9.5 15.8 12.4 19.0 27.8 7.2 17.5 26.0 13.8 12.8 11.7 10.9 8.9 26.8 29.9 9.3 77.6 14.2 11.0 19.3 19.5 26.6 5.9 10.1 12.2 22.9 5.3 14.3 5.3 50.1 9.6 2.6 50.7 25.6 9.8 0.2 1.1 1.8 0.4 79.6 23.1 26.1 0.7 2.0 0.3 0.9 0.0 0.3 0.2 24.1 2.4 0.3 0.7 0.1 33.7 0.1 0.1 0.2 0.4 0.4 61.7 120.7 0.0 0.0 95.4 7.2 2.5 2.5 0.4 0.3 0.8 0.3 0.1 1.2 0.8 0.2 0.4 0.3 0.0 1.4 0.5 0.3 0.2 0.4 0.1 0.6 129.8 0.1 0.0 2.7 5.9 0.2 0.6 0.2 3.1 1.6 0.3 0.0 1.2 0.3 0.3 0.2 0.3 9.9 0.0 0.1 0.1 0.2 0.1 0.1 1.6 0.1 0.0 0.1 2.2 0.2 0.5 0.9 1.0 0.0 0.0 0.2 0.2 10.1 10.7 20.6 13.6 9.5 15.8 17.5 26.0 26.8 10.1 14.3 9.8 94.3 3.2 2.0 2.0 3.5 10.8 1.3 17.3 3.4 38.5 1.4 5.7 6.1 0.0 6.7 0.0 0.0 1.4 1.9 0.1 0.0 0.8 0.7 2.9 4.2 23.1 0.0 0.0 2.4 0.2 0.6 87.6 1.5 0.7 0.0 0.2 2.2 1.2 0.4 8.4 12.3 0.0 0.0 0.0 13.3 2.5 95.7 2.6 78.2 3.7 0.0 22.1 0.0 1.0 1.0 0.1 0.0 23.3 0.6 0.8 0.0 0.2 21.1 12.9 92.1 21.8 95.6 1.6 1.4 0.7 6.7 2.9 2.6 9.2 0.0 1.0 CYP4V2 CYP4AH1 ENSG00000145476 "Cytochrome P450 family 4 subfamily V member 2" Q6ZWL3 4 186191567-186213463 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism, Sensory transduction, Vision" "Monooxygenase, Oxidoreductase" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 113.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 103.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 15.2;SK-MEL-30: 27.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029122 Approved Approved "Nuclear speckles" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 2: Hepatocytes - Metabolism" "Nuclear speckles" "HPA029122: AB_10601806" "unprognostic (1.65e-1)" "unprognostic (5.37e-2)" "unprognostic (2.35e-1)" "prognostic favorable (5.86e-4)" "unprognostic (1.45e-1)" "unprognostic (1.02e-1)" "prognostic favorable (1.85e-4)" "unprognostic (6.66e-2)" "unprognostic (5.84e-2)" "unprognostic (2.05e-1)" "unprognostic (6.49e-2)" "unprognostic (9.89e-2)" "prognostic favorable (1.49e-7)" "unprognostic (3.25e-2)" "unprognostic (8.96e-2)" "unprognostic (1.02e-1)" "unprognostic (3.14e-2)" 7.4 16.4 5.1 5.2 6.8 2.1 5.7 5.6 5.0 8.6 17.9 9.6 16.5 5.6 2.6 5.0 6.1 14.7 9.2 4.8 5.1 33.9 113.5 10.8 5.6 5.3 6.0 5.7 15.6 33.4 3.7 3.5 5.3 8.2 11.9 14.2 7.0 7.5 4.5 1.3 16.7 7.1 5.4 11.2 6.2 3.2 5.6 6.5 17.3 5.0 4.9 6.4 2.3 6.3 3.4 1.8 0.8 0.0 15.2 6.3 0.2 4.4 9.9 1.7 1.9 0.0 13.0 1.1 0.5 3.5 5.9 1.6 1.9 1.7 0.3 6.0 2.2 4.7 0.8 0.5 5.6 2.6 1.9 5.8 0.8 1.9 1.0 5.9 0.1 6.4 1.4 14.3 6.8 2.9 3.6 1.3 1.5 1.6 0.0 3.1 0.7 1.0 7.4 6.1 4.0 4.9 1.1 0.0 27.5 0.3 2.6 4.6 4.1 3.6 0.7 3.5 1.6 0.1 0.0 0.5 10.9 11.0 4.7 0.0 0.6 0.0 1.8 1.9 1.0 0.4 1.4 1.8 0.7 1.0 1.3 1.3 0.0 0.8 3.1 1.3 1.1 0.9 5.1 6.8 5.6 5.0 4.8 5.1 5.3 6.0 5.3 5.4 5.6 6.3 9.0 6.4 11.5 31.3 13.8 2.5 4.5 5.1 9.6 33.6 9.3 7.2 18.8 42.9 8.7 14.7 31.3 2.0 9.6 14.7 9.8 24.2 2.7 6.7 5.1 7.7 16.9 16.4 15.4 22.4 2.1 14.2 12.8 7.6 7.0 6.5 8.9 103.7 13.5 5.0 23.4 16.5 2.0 14.8 6.0 2.1 5.0 11.3 3.6 6.5 3.5 52.2 4.1 15.6 11.0 9.6 9.0 6.4 12.3 3.8 47.2 28.5 11.9 27.4 0.0 10.1 10.6 8.9 6.3 6.8 3.1 1.0 17.2 6.7 10.5 5.7 CYSRT1 "C9orf169, MGC59937" ENSG00000197191 "Cysteine rich tail 1" A8MQ03 9 137224635-137226315 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "esophagus: 239.5" "Group enriched" "Detected in some" 10 "Pancreatic endocrine cells: 58.0;Squamous epithelial cells: 66.0" "Cancer enhanced" "Detected in all" "head and neck cancer: 23.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 25.1;CAPAN-2: 28.9;HaCaT: 33.3;HeLa: 30.6;MCF7: 49.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA021883, HPA021886" Approved Approved "Nuclear speckles,Vesicles,Midbody" Yes No "Cluster 7: Monocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 61: Squamous epithelial cells - Keratinization" "Nuclear speckles" "Vesicles, Midbody" "HPA021883: AB_1853190, HPA021886: AB_1853192" "unprognostic (1.35e-1)" "unprognostic (2.53e-2)" "unprognostic (8.31e-3)" "unprognostic (6.87e-3)" "unprognostic (2.14e-1)" "unprognostic (2.66e-2)" "unprognostic (8.11e-2)" "unprognostic (5.86e-2)" "unprognostic (3.45e-1)" "unprognostic (2.73e-1)" "unprognostic (1.24e-2)" "unprognostic (1.05e-1)" "unprognostic (6.24e-3)" "unprognostic (7.92e-3)" "unprognostic (1.99e-1)" "unprognostic (1.03e-1)" "unprognostic (2.29e-1)" 0.6 1.1 0.6 0.2 0.4 0.4 1.5 0.3 1.6 43.1 0.0 0.6 0.4 0.5 0.4 239.5 1.8 0.7 0.9 0.8 0.8 3.7 1.7 1.1 0.7 1.4 1.3 0.3 1.5 0.6 7.3 0.3 0.6 2.6 0.1 0.6 29.9 0.5 0.4 34.4 0.8 0.0 1.0 0.7 2.0 4.1 0.9 0.3 2.4 0.0 14.3 1.2 57.7 0.5 25.1 2.4 1.8 3.9 0.0 0.1 5.3 0.4 0.4 0.5 0.2 1.3 28.9 1.3 1.2 0.3 0.7 33.3 0.5 7.0 0.0 2.7 1.8 0.3 30.6 16.8 0.9 0.2 1.4 0.4 3.5 0.9 0.2 1.3 0.3 1.4 0.6 3.1 1.6 49.5 0.7 1.0 0.7 4.8 3.0 2.4 2.8 3.5 0.6 1.6 0.4 1.8 4.5 3.5 0.9 1.5 7.7 0.4 1.0 1.1 0.9 3.2 0.6 1.9 1.7 1.2 1.4 1.3 1.4 0.2 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.9 0.0 0.0 0.0 0.6 0.4 0.3 1.6 0.8 0.8 1.4 1.3 0.6 1.0 0.9 0.5 0.0 0.0 1.1 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.7 0.5 0.4 1.5 2.5 5.5 0.0 0.6 0.1 0.4 0.0 4.6 0.5 2.1 0.2 0.3 0.0 0.0 0.3 5.8 0.2 0.1 3.1 1.7 0.0 0.6 0.7 0.8 0.2 0.0 0.3 0.6 0.0 0.3 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.5 0.0 0.0 0.0 58.0 1.1 0.4 0.1 0.2 1.6 0.9 0.0 0.6 0.0 0.3 0.3 3.0 1.1 66.0 0.0 0.0 0.1 0.9 0.5 1.7 DACH1 DACH ENSG00000276644 "Dachshund family transcription factor 1" Q9UI36 13 71437966-71867204 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 88.5;Excitatory neurons: 77.0;Horizontal cells: 87.5;Late spermatids: 103.7;Microglial cells: 143.4;Muller glia cells: 143.8;Spermatocytes: 58.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "basophil: 4.2;eosinophil: 8.4;NK-cell: 4.2;plasmacytoid DC: 6.4" "Group enriched" "Detected in many" 33 "dendritic cells: 6.4;granulocytes: 8.4;NK-cells: 4.2" "Cell line enhanced" "Detected in some" "AF22: 14.2;HAP1: 22.5;HEK 293: 16.8;HL-60: 37.9;NB-4: 16.7;SCLC-21H: 36.9;SH-SY5Y: 29.5;THP-1: 26.9" "Region enriched" "Detected in all" 5 "basal ganglia: 38.8" "Region enriched" "Detected in all" 5 "basal ganglia: 34.2" "HPA012672, HPA012938, HPA073222" Approved Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Nuclear speckles" "HPA012672: AB_1847466, HPA012938: , HPA073222: " "unprognostic (3.16e-1)" "unprognostic (5.26e-2)" "unprognostic (1.41e-2)" "unprognostic (2.36e-1)" "unprognostic (4.21e-2)" "unprognostic (5.63e-2)" "unprognostic (2.22e-2)" "unprognostic (8.08e-3)" "unprognostic (2.12e-2)" "unprognostic (2.50e-1)" "unprognostic (3.04e-3)" "unprognostic (4.37e-1)" "unprognostic (2.18e-2)" "unprognostic (1.06e-1)" "unprognostic (2.19e-1)" "unprognostic (1.24e-1)" "unprognostic (5.17e-2)" 4.4 11.1 2.3 1.2 14.0 6.0 4.0 1.6 2.9 9.7 0.3 3.1 5.2 3.8 1.3 0.9 2.8 7.2 2.2 1.0 4.6 8.9 2.0 5.9 0.5 7.0 9.3 0.5 1.9 6.6 3.5 6.9 5.9 7.0 3.3 16.7 2.0 2.3 1.9 1.8 6.7 2.0 2.6 5.4 1.9 6.3 4.3 3.5 0.2 1.2 0.4 2.0 2.7 2.4 0.0 0.0 14.2 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 22.5 0.0 0.0 0.0 16.8 0.2 0.0 0.0 0.4 37.9 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.9 16.7 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 36.9 29.5 0.0 0.0 0.0 0.1 0.9 26.9 0.0 0.4 0.3 0.0 0.8 0.0 0.0 0.0 1.0 0.0 0.2 4.2 0.1 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 4.2 0.0 6.4 0.0 0.1 2.3 14.0 1.6 2.9 1.0 4.6 7.0 9.3 5.9 2.6 4.3 2.4 36.4 0.0 0.6 15.7 0.5 1.7 3.6 0.0 0.0 15.4 19.4 9.3 2.1 1.5 0.0 7.3 4.2 0.0 12.5 0.9 5.9 1.0 88.5 5.0 4.7 34.2 34.1 2.5 77.0 0.0 0.0 4.6 1.1 3.2 5.1 0.3 2.9 0.0 0.2 87.5 28.2 21.4 0.0 1.2 1.2 103.7 3.4 2.5 0.0 143.4 1.1 143.8 0.0 6.6 3.9 0.6 0.3 1.9 0.0 5.8 3.5 6.9 0.7 6.9 13.1 1.5 4.3 58.8 10.2 0.2 1.3 0.0 1.0 1.3 12.6 2.7 DAZAP2 KIAA0058 ENSG00000183283 "DAZ associated protein 2" Q15038 12 51238724-51271362 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045940 Supported "Nuclear speckles" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 3: HMC-1 - Innate immune response" "Cluster 59: Non-specific - Transcription" "Nuclear speckles" "HPA045940: AB_2679506" "unprognostic (1.00e-2)" "unprognostic (3.13e-2)" "unprognostic (7.35e-2)" "unprognostic (3.44e-2)" "unprognostic (1.00e-1)" "unprognostic (5.47e-2)" "unprognostic (4.75e-3)" "unprognostic (8.43e-2)" "unprognostic (4.75e-2)" "unprognostic (3.30e-1)" "unprognostic (5.80e-2)" "unprognostic (1.42e-1)" "prognostic favorable (3.94e-9)" "unprognostic (1.79e-1)" "unprognostic (2.40e-1)" "unprognostic (3.04e-1)" "unprognostic (5.84e-3)" 136.4 115.7 112.2 187.5 125.3 613.5 154.0 136.6 124.4 150.5 109.8 206.2 194.9 131.6 122.5 129.9 180.5 168.0 202.1 105.1 125.9 251.4 198.4 193.2 220.6 132.7 119.8 114.1 116.5 227.3 30.7 79.5 134.4 152.8 215.5 75.2 140.7 171.8 113.5 121.4 200.5 148.4 129.8 224.3 174.3 52.7 116.5 213.2 209.8 106.7 241.5 190.3 76.3 151.5 159.8 209.0 95.4 92.2 201.1 171.5 57.6 104.6 208.9 187.7 162.8 155.9 239.0 153.2 262.2 209.9 130.0 147.8 134.2 178.4 189.2 167.3 160.2 227.1 129.7 91.0 216.4 265.5 350.2 220.5 252.1 175.3 147.2 207.2 234.8 118.8 141.6 303.1 155.4 252.6 219.8 145.6 19.6 109.2 58.7 123.2 144.7 165.3 244.9 260.2 103.3 101.0 159.3 137.9 121.3 56.7 190.5 382.7 195.7 111.1 102.4 136.9 132.6 231.5 237.5 158.6 161.2 175.0 66.9 2018.1 2144.1 3354.3 1055.9 1770.0 979.3 1090.7 962.8 1037.9 1354.1 1068.7 1063.1 918.3 3499.5 1045.4 1727.1 875.9 1420.3 4885.3 112.2 125.3 136.6 124.4 105.1 125.9 132.7 119.8 134.4 129.8 116.5 151.5 116.7 144.2 205.1 19.6 271.9 113.8 201.2 144.6 167.9 50.6 127.7 88.5 114.3 165.8 127.9 235.4 58.4 55.8 167.4 337.2 266.1 158.6 28.1 115.1 87.2 138.3 126.3 155.6 16.8 194.7 53.5 108.0 171.8 142.1 182.2 72.2 157.1 177.1 209.4 67.3 16.8 230.6 140.4 444.4 214.2 85.6 117.4 282.0 135.2 19.7 324.4 88.7 221.4 15.6 43.9 198.0 275.8 95.5 169.5 179.9 233.3 292.7 155.9 55.2 46.0 63.2 130.4 39.4 35.4 153.5 133.3 124.9 249.6 72.8 182.4 268.7 DBNDD1 "FLJ12582, MGC3101" ENSG00000003249 "Dysbindin domain containing 1" Q9H9R9 16 90004871-90019890 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 92.0;skeletal muscle: 48.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 22.8;Ductal cells: 16.0;Exocrine glandular cells: 18.8;Horizontal cells: 30.3;Pancreatic endocrine cells: 15.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "naive B-cell: 12.9" "Lineage enriched" "Detected in many" 4 "B-cells: 12.9" "Cell line enhanced" "Detected in many" "MCF7: 139.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043018 Uncertain Approved "Nuclear speckles,Cytosol" No No "Cluster 21: B-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 1: Pancreatic cells - Digestion" "Nuclear speckles" Cytosol "HPA043018: AB_10794921" "unprognostic (1.07e-1)" "unprognostic (8.40e-2)" "unprognostic (8.70e-2)" "unprognostic (1.73e-1)" "unprognostic (1.86e-2)" "unprognostic (4.18e-2)" "unprognostic (1.51e-1)" "unprognostic (1.70e-1)" "unprognostic (6.07e-2)" "unprognostic (9.52e-2)" "unprognostic (1.54e-1)" "unprognostic (2.86e-2)" "prognostic favorable (2.75e-7)" "unprognostic (1.03e-1)" "unprognostic (5.67e-1)" "unprognostic (2.44e-2)" "unprognostic (2.00e-2)" 1.8 7.4 47.1 2.5 35.3 0.3 4.4 27.5 60.6 4.1 11.6 2.9 1.6 0.9 10.0 28.2 3.6 3.8 4.6 35.2 40.7 13.3 6.5 3.5 4.7 50.6 55.3 3.1 19.5 9.6 7.7 0.1 50.8 3.8 1.4 7.4 15.5 3.1 48.0 6.0 1.7 1.3 30.3 1.2 7.7 1.0 92.0 1.4 5.2 4.8 5.1 1.7 7.3 38.6 22.8 34.7 3.5 44.7 0.9 0.4 24.7 4.9 6.6 10.5 5.3 32.1 19.7 0.0 2.7 1.1 10.2 24.0 41.3 1.2 10.7 0.1 65.4 0.0 4.4 58.6 1.5 0.3 4.7 1.0 3.3 18.8 0.1 25.2 47.3 0.8 6.7 0.4 4.1 139.7 0.1 33.5 59.5 18.6 13.9 14.5 32.3 0.6 64.2 4.5 51.2 53.0 5.6 5.3 44.8 10.2 34.6 4.8 36.2 7.4 15.1 0.4 24.1 0.3 0.3 0.4 3.5 3.9 20.1 0.0 0.0 0.7 0.0 0.0 0.0 1.2 0.6 0.5 0.0 12.9 2.9 0.5 0.0 0.0 0.0 0.1 0.0 1.0 47.1 35.3 27.5 60.6 35.2 40.7 50.6 55.3 50.8 30.3 92.0 38.6 0.3 3.2 2.0 2.9 6.0 0.4 0.6 0.6 0.0 1.8 13.5 7.5 2.5 22.8 2.0 9.2 0.0 0.2 0.1 1.4 9.8 16.0 0.0 5.7 0.7 1.1 6.0 0.0 6.1 18.8 0.3 0.2 2.6 7.8 0.0 3.4 1.4 2.5 0.3 30.3 3.6 1.5 2.0 0.0 0.7 0.0 1.2 0.1 3.6 2.8 0.2 10.4 0.0 1.5 0.7 15.0 2.9 0.4 0.5 4.3 0.2 10.8 2.7 1.8 0.0 1.4 1.2 0.1 2.0 8.1 1.0 0.0 1.4 0.3 0.8 1.3 DDX17 P72 ENSG00000100201 "DEAD-box helicase 17" Q92841 22 38483438-38507660 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Immunity, mRNA processing, mRNA splicing, RNA-mediated gene silencing, rRNA processing, Transcription, Transcription regulation" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB024908, HPA063142" Supported Supported "Nuclear speckles" "Intracellular and membrane" NA NA 420000 "Cluster 1: Neutrophils - Mixed function" "Cluster 51: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "CAB024908: , HPA063142: AB_2684949" "unprognostic (1.46e-2)" "unprognostic (5.99e-3)" "unprognostic (4.24e-3)" "unprognostic (6.67e-2)" "unprognostic (1.06e-2)" "unprognostic (1.02e-2)" "unprognostic (1.36e-2)" "prognostic favorable (6.06e-4)" "unprognostic (1.17e-1)" "unprognostic (5.51e-1)" "unprognostic (2.52e-2)" "unprognostic (2.73e-2)" "unprognostic (1.89e-2)" "unprognostic (2.19e-2)" "unprognostic (1.76e-1)" "unprognostic (4.31e-2)" "unprognostic (3.19e-3)" 181.2 172.4 142.0 124.3 160.1 74.5 198.5 150.9 178.4 248.7 174.8 233.8 107.8 216.1 255.3 150.4 248.1 121.1 168.7 143.5 152.1 247.2 152.8 202.2 186.4 152.8 149.4 298.8 214.0 144.7 309.9 158.8 155.3 234.4 114.2 342.0 188.4 123.3 184.8 197.0 227.2 119.7 146.8 293.0 192.1 91.1 148.2 215.2 300.0 106.6 158.2 204.4 201.5 196.5 122.0 79.9 237.6 141.8 148.2 166.0 120.7 104.3 85.9 118.3 121.2 89.0 100.5 225.8 65.8 119.5 82.9 133.2 212.5 127.9 145.9 202.5 142.1 140.4 175.8 133.5 153.4 192.9 170.8 122.3 183.7 86.8 142.9 211.7 153.3 109.6 139.7 255.3 116.0 75.6 128.7 164.0 148.0 172.1 51.6 218.0 122.9 137.1 141.2 132.6 134.1 75.3 155.0 125.9 161.2 180.5 110.0 148.4 140.8 125.7 77.6 80.0 79.3 203.7 130.3 183.4 156.7 123.1 154.2 6.7 8.1 9.5 7.6 7.9 8.9 9.0 7.1 7.3 7.0 7.2 5.7 6.8 16.6 5.1 8.7 10.5 9.1 6.0 142.0 160.1 150.9 178.4 143.5 152.1 152.8 149.4 155.3 146.8 148.2 196.5 252.6 214.7 325.5 483.8 241.9 223.6 206.1 129.3 158.2 448.3 300.7 195.3 147.2 180.1 223.5 283.3 352.3 127.6 297.5 172.8 33.2 111.7 44.4 280.0 293.4 250.4 236.1 177.1 198.9 90.2 99.9 207.5 216.1 234.2 200.7 505.3 233.8 205.3 113.9 321.4 242.1 191.6 146.5 200.6 194.8 49.1 323.7 197.7 154.7 253.9 235.1 223.4 304.9 334.3 553.3 104.7 153.1 278.7 213.1 193.5 154.8 89.8 270.8 559.4 289.3 260.5 213.6 136.4 74.2 120.4 279.9 139.4 218.6 293.7 147.0 255.3 DDX39A "BAT1L, DDX39, DDXL, URH49" ENSG00000123136 "DExD-box helicase 39A" O00148 19 14408798-14419383 "Enzymes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 147.8" "Cell type enhanced" "Detected in many" "Early spermatids: 308.4;Late spermatids: 283.3;Spermatocytes: 307.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055334 Approved Approved "Nuclear speckles" NA NA 200000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear speckles" "HPA055334: AB_2682787" "unprognostic (1.31e-1)" "prognostic favorable (6.86e-4)" "unprognostic (2.41e-1)" "unprognostic (1.10e-1)" "unprognostic (1.12e-1)" "unprognostic (5.20e-2)" "unprognostic (2.55e-3)" "unprognostic (1.92e-1)" "unprognostic (1.87e-1)" "unprognostic (8.81e-2)" "unprognostic (1.64e-1)" "unprognostic (3.09e-2)" "prognostic unfavorable (1.50e-10)" "unprognostic (1.55e-3)" "unprognostic (8.57e-2)" "unprognostic (3.92e-1)" "unprognostic (7.38e-3)" 28.2 21.6 17.1 49.6 20.7 105.5 24.7 21.9 23.0 22.1 18.0 26.4 28.6 21.9 8.7 39.3 18.2 13.6 24.9 17.0 18.6 21.0 21.9 25.1 76.2 21.9 19.8 14.9 15.7 10.2 15.5 18.1 22.0 16.8 20.2 4.7 19.0 8.8 20.7 24.4 33.8 15.1 19.0 55.7 27.2 147.8 20.5 80.4 20.5 12.7 65.1 25.9 22.7 25.2 198.8 175.9 87.8 147.2 32.4 22.4 73.5 84.8 48.0 176.1 105.7 183.3 98.7 375.0 87.5 71.1 101.0 114.8 215.7 135.9 74.3 129.0 127.3 408.5 201.0 133.1 55.1 225.1 164.0 30.1 30.6 113.1 47.0 25.4 89.1 134.4 253.4 150.3 95.7 270.9 375.4 320.1 147.9 208.8 280.4 248.9 139.7 212.0 62.5 179.6 181.5 98.2 64.3 127.8 98.6 54.3 138.0 216.5 83.1 144.5 92.7 245.7 192.6 156.0 313.0 399.3 167.1 232.2 148.9 33.2 92.8 29.6 120.1 107.9 106.2 132.5 96.0 96.3 131.1 125.8 83.1 90.1 27.0 84.1 94.3 82.7 153.0 135.5 17.1 20.7 21.9 23.0 17.0 18.6 21.9 19.8 22.0 19.0 20.5 25.2 55.6 16.0 21.4 4.9 90.0 76.0 43.6 53.0 50.1 10.5 30.0 24.8 10.9 21.5 27.4 5.5 0.0 60.6 75.1 60.5 37.2 55.3 308.4 26.6 30.6 53.0 25.7 88.1 3.1 67.2 117.9 33.3 87.7 44.5 93.0 32.7 26.0 12.9 90.5 11.8 3.5 55.4 26.4 48.6 85.2 283.3 26.4 62.7 49.8 4.7 56.7 16.2 50.4 4.0 9.2 53.5 42.7 18.8 115.6 44.5 41.7 26.0 21.1 4.9 19.7 24.8 62.0 307.5 95.4 69.4 71.0 59.9 78.7 32.1 63.8 34.2 DDX39B "BAT1, D6S81E, UAP56" ENSG00000198563 "DExD-box helicase 39B" Q13838 6 31530219-31542448 "Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters" "mRNA processing, mRNA splicing, mRNA transport, Transport" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEK 293: 352.9;hTERT-HME1: 244.9;K-562: 255.5;NB-4: 254.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034012, HPA055334, HPA058450" Enhanced Enhanced "Nuclear speckles" NA NA 270000 "Cluster 32: T-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "CAB034012: AB_2243237, HPA055334: AB_2682787, HPA058450: AB_2683721" "unprognostic (2.78e-2)" "unprognostic (1.30e-2)" "unprognostic (6.86e-3)" "unprognostic (3.44e-2)" "unprognostic (3.22e-2)" "unprognostic (5.13e-3)" "unprognostic (2.89e-2)" "unprognostic (1.19e-2)" "unprognostic (4.89e-3)" "unprognostic (1.25e-1)" "unprognostic (2.81e-2)" "unprognostic (3.53e-3)" "prognostic unfavorable (1.11e-6)" "unprognostic (2.85e-1)" "unprognostic (1.72e-1)" "unprognostic (1.90e-2)" "prognostic favorable (1.43e-5)" 130.5 138.3 11.9 23.7 12.3 5.5 125.0 12.8 13.1 147.7 12.0 126.6 3.0 127.6 103.5 105.9 133.9 6.2 141.8 11.4 12.4 123.0 125.9 117.5 34.5 14.4 12.5 173.0 187.5 7.9 125.0 14.6 12.6 141.8 16.6 34.3 103.1 30.3 181.6 104.3 134.1 9.5 13.5 178.1 117.0 59.8 12.0 40.1 133.4 60.4 26.4 118.6 113.2 14.6 9.0 130.9 37.7 19.7 121.4 78.1 24.7 9.6 11.5 28.8 25.4 13.3 17.8 24.3 75.0 145.0 106.3 16.5 42.8 223.1 26.7 8.1 352.9 19.9 14.3 28.7 13.2 35.1 18.8 129.0 117.8 28.9 244.9 131.0 18.3 157.0 255.5 7.1 24.1 6.3 22.7 254.1 17.2 18.3 13.0 17.9 41.6 10.8 143.5 11.8 18.4 151.2 26.3 9.0 15.6 35.7 6.5 36.5 10.3 3.7 13.9 3.6 26.7 68.2 78.9 229.9 2.3 39.5 16.6 2.5 6.4 4.8 4.8 7.6 6.4 4.2 6.9 6.7 9.3 6.2 10.2 8.8 4.3 5.2 4.6 7.7 7.1 5.6 11.9 12.3 12.8 13.1 11.4 12.4 14.4 12.5 12.6 13.5 12.0 14.6 31.5 22.4 36.9 0.0 43.9 14.4 41.9 13.2 35.9 21.3 21.8 15.7 4.0 5.7 22.2 3.7 22.9 13.9 58.1 15.2 5.9 9.7 1.4 23.0 37.8 26.5 17.3 26.3 0.0 8.2 11.8 28.0 64.2 32.4 37.2 58.3 13.2 6.9 9.8 15.2 0.0 11.7 12.2 14.8 14.4 2.6 16.1 34.9 8.8 0.0 17.1 8.5 66.9 0.0 0.0 10.4 11.7 11.7 44.5 23.0 17.5 5.1 31.5 27.2 26.3 57.9 35.2 6.4 6.7 44.2 13.5 17.0 50.3 79.6 12.7 33.9 DDX42 "RHELP, RNAHP, SF3b125, SF3B8" ENSG00000198231 "DEAD-box helicase 42" Q86XP3 17 63773603-63819317 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023447, HPA023571, HPA025941" Approved Enhanced "Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "HPA023447: AB_1847560, HPA023571: AB_1847561, HPA025941: AB_1847562" "unprognostic (3.46e-1)" "unprognostic (7.11e-2)" "unprognostic (8.44e-2)" "unprognostic (1.29e-1)" "unprognostic (2.49e-2)" "unprognostic (3.17e-2)" "prognostic unfavorable (2.84e-4)" "unprognostic (1.06e-1)" "unprognostic (4.73e-2)" "unprognostic (1.90e-1)" "unprognostic (2.54e-2)" "unprognostic (1.34e-2)" "prognostic unfavorable (9.26e-4)" "unprognostic (3.02e-1)" "unprognostic (2.42e-1)" "unprognostic (7.35e-2)" "unprognostic (1.55e-2)" 43.5 32.6 27.4 30.5 29.4 37.3 42.7 26.2 29.7 38.5 21.6 42.9 31.3 42.4 39.0 32.6 44.0 30.2 35.3 25.8 30.8 30.0 34.8 35.8 40.6 29.9 30.1 54.7 54.4 39.9 29.2 36.5 28.9 39.3 36.4 39.3 47.3 40.7 59.2 39.6 33.5 43.1 29.0 37.2 37.1 39.8 30.7 40.1 34.2 42.7 47.1 39.5 30.6 26.5 87.4 89.9 79.2 81.3 78.2 62.7 85.0 83.4 74.6 74.7 72.9 84.7 55.9 120.8 32.0 94.3 62.4 68.2 90.3 74.3 98.5 35.9 59.1 91.0 92.0 104.2 77.1 106.9 59.7 80.3 69.2 67.9 81.6 63.5 75.2 61.6 103.2 49.7 77.0 71.3 102.8 59.3 75.8 69.4 47.4 88.7 135.8 62.3 68.2 101.3 49.5 93.9 63.2 112.3 74.1 110.7 77.2 87.1 80.5 109.9 67.0 45.3 99.4 55.6 47.9 109.5 56.4 58.1 58.9 1.9 2.2 6.9 3.7 2.2 4.2 2.8 3.0 3.7 2.9 5.3 3.6 3.7 2.0 4.5 4.3 1.8 2.1 1.9 27.4 29.4 26.2 29.7 25.8 30.8 29.9 30.1 28.9 29.0 30.7 26.5 41.5 80.1 60.4 24.2 34.7 31.2 24.4 24.5 48.9 40.9 37.0 38.0 49.5 30.0 49.0 36.8 37.5 33.3 29.3 27.0 13.7 30.4 9.2 64.9 68.0 41.8 40.7 33.0 33.6 27.1 24.4 42.2 32.1 72.0 30.4 82.1 30.0 34.5 23.2 50.5 30.3 37.8 28.5 32.7 26.1 12.7 48.7 29.6 14.2 21.5 55.5 46.6 32.0 18.1 26.7 41.1 25.3 50.4 36.7 39.0 26.5 23.5 65.5 46.7 39.5 63.2 51.8 68.5 63.1 52.7 29.7 27.4 32.7 71.3 33.8 32.4 DDX46 "FLJ25329, KIAA0801, Prp5, PRPF5" ENSG00000145833 "DEAD-box helicase 46" Q7L014 5 134758771-134855133 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036554, HPA057501" Supported Supported "Nucleoli fibrillar center,Nuclear speckles" NA NA 13000 "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "Nucleoli fibrillar center" "HPA036554: AB_10673621, HPA057501: AB_2683449" "unprognostic (1.88e-1)" "unprognostic (1.21e-1)" "prognostic favorable (9.01e-6)" "unprognostic (7.00e-2)" "unprognostic (3.37e-2)" "unprognostic (1.71e-2)" "unprognostic (2.04e-3)" "unprognostic (1.07e-1)" "unprognostic (1.60e-2)" "unprognostic (5.05e-2)" "unprognostic (9.21e-2)" "unprognostic (6.02e-2)" "unprognostic (9.70e-3)" "unprognostic (4.36e-2)" "unprognostic (4.35e-2)" "unprognostic (1.64e-2)" "unprognostic (4.50e-2)" 16.5 14.6 7.6 23.9 8.8 23.1 17.7 16.1 10.8 16.3 11.4 17.3 17.0 19.8 12.3 17.5 15.0 13.4 13.4 6.8 11.2 18.8 17.7 15.8 25.6 10.0 8.4 18.5 20.8 18.4 11.1 15.7 9.2 15.5 20.7 18.0 16.8 12.1 35.2 19.4 18.7 17.6 5.4 20.6 20.0 16.3 10.0 32.1 18.7 22.9 26.6 18.2 15.6 10.3 87.1 78.0 54.4 71.1 20.8 23.2 75.0 56.8 43.7 58.8 65.6 119.2 61.7 108.9 47.7 38.3 62.3 52.5 80.9 54.2 68.7 73.8 73.3 131.0 84.7 48.5 18.0 120.5 67.8 21.0 28.9 62.1 34.8 24.9 47.3 85.9 113.6 45.3 44.1 41.5 104.2 46.9 75.2 50.1 34.8 89.7 142.0 54.8 32.0 73.9 64.2 61.3 79.4 37.2 42.7 63.0 58.3 68.0 59.0 61.8 43.2 47.9 114.0 35.6 103.2 140.2 42.8 112.0 40.0 55.6 31.9 48.2 30.7 29.2 28.0 38.1 30.4 31.3 25.3 43.4 30.9 31.5 55.9 32.3 27.5 38.5 29.7 17.8 7.6 8.8 16.1 10.8 6.8 11.2 10.0 8.4 9.2 5.4 10.0 10.3 102.4 76.9 131.5 35.9 123.6 113.8 121.5 102.7 68.9 131.5 80.6 79.4 69.3 64.3 94.9 103.0 83.4 133.7 142.3 91.3 56.7 100.5 53.4 111.4 155.8 104.7 92.2 90.6 38.7 107.9 160.4 85.1 69.3 115.9 101.2 122.3 76.8 113.1 94.4 121.1 41.2 112.4 63.1 119.3 113.2 26.7 111.9 103.4 56.9 21.5 178.5 79.9 194.7 28.1 57.6 130.7 62.6 113.2 134.7 139.5 79.2 84.1 74.5 176.0 98.6 114.9 115.2 246.3 275.7 81.0 137.0 157.2 131.8 114.5 112.7 144.1 DENND1B "C1orf218, FAM31B, FLJ20054, MGC27044" ENSG00000213047 "DENN domain containing 1B" Q6P3S1 1 197504748-197775696 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 101.3;Inhibitory neurons: 138.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 19.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042586 Uncertain Supported "Nuclear speckles,Cytosol" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Nuclear speckles" "HPA042586: AB_2678064" "unprognostic (8.79e-2)" "unprognostic (1.58e-1)" "unprognostic (4.25e-2)" "unprognostic (1.20e-1)" "unprognostic (2.39e-1)" "unprognostic (7.13e-3)" "unprognostic (2.69e-1)" "unprognostic (9.54e-2)" "unprognostic (7.79e-3)" "unprognostic (3.99e-2)" "unprognostic (3.13e-2)" "unprognostic (5.36e-2)" "unprognostic (6.11e-2)" "unprognostic (5.61e-3)" "unprognostic (1.96e-1)" "unprognostic (1.52e-1)" "unprognostic (2.35e-2)" 2.0 2.7 2.4 3.8 8.3 5.6 5.7 3.9 3.0 3.1 1.5 6.0 5.7 2.1 4.0 4.4 2.0 3.4 5.8 2.1 4.4 5.6 5.0 4.3 6.5 2.9 5.3 4.0 5.8 5.9 2.5 1.5 3.6 3.8 5.7 5.9 4.5 3.2 3.9 1.9 6.9 1.9 1.9 4.3 4.8 2.2 4.5 6.6 6.0 5.9 6.5 4.0 2.8 2.6 7.2 1.8 2.0 3.4 0.9 5.0 3.0 5.4 3.7 3.3 2.0 1.9 4.5 13.0 2.7 8.3 1.9 3.6 3.2 3.9 2.9 10.0 3.4 4.7 3.7 0.9 2.7 15.5 5.6 1.7 5.2 1.3 3.6 10.0 1.4 7.4 3.6 19.6 3.3 1.3 8.3 7.9 0.7 1.8 1.7 5.1 1.7 10.3 7.9 6.6 3.4 5.3 8.3 5.5 1.5 3.1 2.3 13.4 4.0 0.4 3.1 0.2 3.2 9.8 0.0 6.4 3.4 6.2 6.2 2.3 0.1 1.1 0.9 0.3 0.4 1.2 0.6 1.4 0.7 0.3 0.3 0.6 0.4 2.7 0.3 0.9 1.8 0.3 2.4 8.3 3.9 3.0 2.1 4.4 2.9 5.3 3.6 1.9 4.5 2.6 9.1 41.7 16.2 46.4 24.1 8.4 23.6 9.2 12.0 18.3 28.9 11.9 28.3 15.7 17.3 14.7 25.0 10.4 22.1 65.5 17.6 9.7 26.8 7.9 5.7 6.5 14.4 8.0 101.3 23.1 9.7 10.9 20.9 17.1 64.7 12.8 9.3 15.3 18.9 5.0 138.5 27.4 4.1 18.9 82.4 26.8 23.9 30.0 16.0 42.2 15.8 8.6 28.8 75.4 5.8 22.5 54.5 13.2 50.7 21.9 59.9 16.4 9.6 14.0 0.0 13.9 6.3 8.1 13.9 22.9 12.1 7.4 42.5 5.7 27.9 53.5 DEXI MYLE ENSG00000182108 "Dexi homolog" O95424 16 10928891-10942468 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 106.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041511 Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 22: Epithelial cell types - Mixed function" "Nuclear speckles" Cytosol "HPA041511: AB_10796675" "unprognostic (4.14e-1)" "unprognostic (8.52e-2)" "unprognostic (1.29e-1)" "unprognostic (9.70e-3)" "unprognostic (1.42e-1)" "unprognostic (2.71e-2)" "unprognostic (1.19e-2)" "unprognostic (4.71e-2)" "unprognostic (3.20e-1)" "unprognostic (1.47e-2)" "prognostic favorable (4.23e-4)" "unprognostic (5.21e-2)" "unprognostic (1.33e-3)" "unprognostic (5.52e-3)" "unprognostic (1.66e-1)" "unprognostic (3.75e-2)" "unprognostic (1.83e-2)" 34.7 82.2 52.6 10.8 54.2 5.5 29.3 59.3 60.1 35.3 44.3 46.8 14.6 34.5 23.4 25.0 34.1 11.2 101.6 43.0 54.0 33.1 91.3 27.3 12.5 58.7 55.6 34.6 29.8 20.9 38.0 13.0 62.2 39.1 7.9 6.2 23.5 20.3 128.4 27.6 24.9 15.5 51.8 30.5 34.0 14.8 67.9 11.6 28.4 58.7 10.5 33.5 28.9 45.5 18.1 25.9 13.6 24.1 54.1 29.5 12.5 27.2 28.0 17.4 16.5 12.2 18.5 21.4 39.9 31.0 19.0 22.9 16.2 29.3 14.9 50.4 36.4 10.7 17.1 52.3 30.9 18.3 19.3 30.2 33.1 17.1 19.7 28.2 25.3 29.7 24.5 20.8 19.6 31.9 22.9 19.9 19.1 22.3 26.5 21.2 18.0 32.8 21.9 13.3 28.0 24.7 26.0 28.2 22.6 11.4 22.5 31.6 28.1 17.5 18.7 41.9 18.0 27.2 22.6 6.2 15.4 38.7 20.2 1.3 0.5 7.2 4.6 0.6 4.2 0.5 4.0 5.4 0.3 4.1 4.7 4.6 0.5 3.0 0.2 2.0 3.3 1.0 52.6 54.2 59.3 60.1 43.0 54.0 58.7 55.6 62.2 51.8 67.9 45.5 23.3 6.4 12.1 10.1 12.4 33.3 40.5 9.7 21.6 18.8 19.1 26.0 0.0 41.5 5.9 27.6 12.5 28.1 11.5 8.5 76.3 24.8 8.1 10.5 21.4 27.1 14.9 15.6 8.0 36.2 21.4 33.8 10.7 7.4 1.3 30.4 46.1 106.3 41.2 23.5 13.3 14.5 14.2 15.5 15.8 14.9 75.2 14.6 16.0 8.4 10.7 57.0 18.6 3.5 6.7 31.2 10.1 85.7 14.9 70.7 17.8 70.9 8.8 14.8 19.7 29.9 26.1 3.8 3.7 18.4 32.5 11.6 19.2 38.4 17.5 39.0 DGKZ "DAGK5, DAGK6, DGK-ZETA, hDGKzeta" ENSG00000149091 "Diacylglycerol kinase zeta" Q13574 11 46332905-46380554 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 146.2" "Cell type enhanced" "Detected in all" "NK-cells: 129.8" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 27 "amygdala: 46.5;basal ganglia: 75.1;cerebral cortex: 146.2;hippocampal formation: 133.8;white matter: 51.0" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051336 Enhanced Supported Supported "Nuclear speckles" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear speckles" "HPA051336: AB_2681448" "unprognostic (2.85e-2)" "unprognostic (3.90e-2)" "unprognostic (2.39e-1)" "unprognostic (1.65e-1)" "unprognostic (1.40e-1)" "unprognostic (4.12e-2)" "unprognostic (3.08e-3)" "unprognostic (1.31e-1)" "unprognostic (1.03e-2)" "unprognostic (2.49e-2)" "unprognostic (3.66e-3)" "unprognostic (8.18e-2)" "prognostic unfavorable (4.74e-5)" "unprognostic (1.48e-3)" "unprognostic (7.75e-2)" "unprognostic (3.61e-2)" "unprognostic (7.84e-3)" 20.7 14.2 46.5 21.6 75.1 54.6 19.4 3.3 146.2 16.5 0.0 20.3 36.4 16.8 4.0 19.5 15.3 11.1 46.5 133.8 0.0 18.3 10.5 18.3 39.9 0.0 0.0 12.4 31.5 10.0 58.7 14.1 0.0 18.6 6.6 2.5 43.4 10.7 95.7 22.3 41.2 9.1 0.0 36.1 22.2 15.4 1.4 34.0 12.5 25.1 17.1 18.2 15.3 51.0 38.1 33.2 22.1 33.2 11.5 12.8 102.1 29.0 21.5 30.0 26.3 39.8 17.1 48.4 20.5 30.1 33.0 43.3 26.7 42.0 10.6 48.8 62.5 31.7 25.2 29.5 20.5 60.5 61.2 17.3 19.3 16.5 22.2 15.3 33.4 39.3 45.1 29.1 21.5 99.8 58.6 94.3 64.3 54.5 50.3 69.0 38.2 20.6 9.1 36.6 150.3 25.6 33.2 109.6 23.0 13.8 78.8 75.2 37.9 39.2 42.4 62.6 52.9 19.1 23.4 40.3 53.8 54.0 37.2 12.4 13.5 6.0 6.8 5.6 4.1 0.3 4.3 5.9 12.0 0.8 4.3 4.6 9.5 7.6 6.4 5.7 4.4 10.5 46.5 75.1 3.3 146.2 133.8 0.0 0.0 0.0 0.0 0.0 1.4 51.0 46.0 3.2 6.6 44.7 16.4 13.3 22.3 16.3 14.2 27.6 24.6 19.8 24.4 8.6 8.7 9.2 20.9 14.6 95.8 37.7 9.8 13.2 6.1 9.9 15.2 34.2 51.5 23.4 114.0 47.8 105.1 12.4 34.1 14.1 21.0 25.7 56.7 7.1 51.2 16.8 45.0 26.3 22.4 46.1 26.9 11.4 13.1 34.0 12.4 31.9 50.6 6.4 129.8 8.5 24.7 33.5 41.0 8.2 25.3 16.6 97.0 20.2 8.2 9.9 32.9 17.8 16.8 7.0 12.2 12.3 9.2 27.4 71.8 19.4 29.9 17.2 DHX15 "DBP1, DDX15, HRH2, PRP43, PRPF43, PrPp43p" ENSG00000109606 "DEAH-box helicase 15" O43143 4 24517441-24584554 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047047 Approved Enhanced "Nuclear speckles" NA NA 130000 "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "HPA047047: AB_2679916" "unprognostic (4.46e-3)" "unprognostic (2.47e-2)" "prognostic favorable (5.74e-4)" "unprognostic (3.35e-1)" "unprognostic (5.30e-2)" "unprognostic (5.74e-2)" "unprognostic (2.06e-3)" "unprognostic (5.53e-3)" "unprognostic (1.51e-1)" "unprognostic (1.39e-1)" "unprognostic (3.60e-2)" "unprognostic (8.68e-3)" "unprognostic (7.77e-3)" "unprognostic (2.51e-3)" "unprognostic (2.19e-1)" "unprognostic (1.59e-1)" "unprognostic (5.41e-3)" 40.3 35.7 17.0 51.2 23.2 78.5 50.7 30.5 22.6 41.3 29.4 48.8 36.8 44.5 30.2 43.9 38.5 35.6 33.3 18.4 20.9 45.7 44.7 37.1 60.2 20.9 20.3 43.8 47.7 52.1 21.6 55.0 22.0 39.5 57.9 40.1 37.7 35.9 43.0 42.1 37.9 48.0 20.8 40.0 44.7 33.5 20.2 79.8 40.0 42.2 70.9 65.6 34.7 29.0 135.0 129.1 209.4 104.6 100.6 97.4 124.7 153.0 133.9 157.8 155.5 132.0 158.5 245.4 91.8 126.2 183.7 109.8 272.1 184.1 243.7 90.6 129.0 213.3 134.7 107.3 59.2 222.3 140.9 82.2 108.4 154.3 103.1 100.8 133.9 113.4 203.4 96.2 181.3 101.3 293.7 148.2 228.4 133.4 115.8 190.4 245.3 114.6 187.1 190.2 179.0 111.9 118.7 112.8 109.1 149.0 123.8 113.7 123.5 132.8 87.5 101.6 181.4 72.1 130.2 289.3 89.1 177.9 161.8 57.5 29.6 28.5 28.8 30.8 39.7 28.7 32.0 33.7 39.0 29.9 33.2 32.2 13.9 37.1 38.5 25.8 38.6 28.5 17.0 23.2 30.5 22.6 18.4 20.9 20.9 20.3 22.0 20.8 20.2 29.0 51.2 76.9 57.4 40.1 53.4 98.7 68.3 58.0 56.3 30.2 50.1 36.7 28.1 35.8 70.6 27.6 22.9 72.7 44.9 79.8 37.2 59.3 32.6 61.7 53.2 53.6 60.5 58.9 51.4 41.8 69.7 55.5 79.5 97.3 57.0 47.4 42.8 48.4 44.7 26.9 50.8 69.3 36.7 46.9 53.2 16.5 39.4 50.2 48.0 49.6 48.0 24.4 34.0 61.3 99.1 57.1 41.2 40.3 51.0 73.1 33.2 34.8 55.6 32.1 26.3 59.6 69.4 72.9 46.3 60.4 100.0 88.2 49.3 34.0 71.2 89.4 DLX2 TES-1 ENSG00000115844 "Distal-less homeobox 2" Q07687 2 172099438-172102900 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 3.0" "Cell type enhanced" "Detected in some" "dendritic cells: 6.5;Early spermatids: 6.9;Gastric mucus-secreting cells: 5.6;Inhibitory neurons: 10.0;Melanocytes: 5.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "hypothalamus: 3.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "AN3-CA: 79.7;HEK 293: 50.8" "Region enhanced" "Detected in many" "olfactory bulb: 29.4" "Region enriched" "Detected in many" 5 "olfactory bulb: 23.2" HPA056965 Approved "Nuclear speckles" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear speckles" "HPA056965: AB_2683291" "unprognostic (8.12e-2)" "unprognostic (3.56e-1)" "unprognostic (2.48e-2)" "unprognostic (1.28e-2)" "unprognostic (4.07e-1)" "unprognostic (2.13e-1)" "unprognostic (8.60e-3)" "unprognostic (3.03e-2)" "unprognostic (2.41e-1)" "unprognostic (8.74e-2)" "unprognostic (3.53e-2)" "unprognostic (3.01e-1)" "unprognostic (6.69e-10)" "unprognostic (9.38e-2)" "unprognostic (2.47e-1)" "unprognostic (2.41e-1)" "unprognostic (7.95e-3)" 0.0 0.3 1.4 0.0 1.1 0.1 0.2 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.7 0.5 0.0 0.5 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 79.7 0.5 0.3 2.2 4.3 1.0 0.7 0.2 0.5 0.2 0.0 2.4 2.0 3.8 4.1 2.6 0.3 0.2 0.1 50.8 1.3 8.8 2.0 0.2 0.4 0.3 0.0 3.7 0.1 0.5 0.3 0.0 2.0 0.6 0.0 0.5 0.2 0.1 0.6 0.1 0.0 1.1 0.0 0.4 0.0 0.1 0.1 2.8 0.0 2.1 1.2 5.0 1.3 0.6 0.4 0.4 5.5 0.0 3.0 0.5 0.1 0.1 0.5 4.7 0.1 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.1 0.0 0.9 0.4 3.0 0.0 0.0 0.0 0.0 0.5 0.1 1.4 0.0 0.0 0.0 1.3 1.8 0.2 0.9 0.6 0.0 3.1 3.6 0.4 0.0 0.2 0.0 0.0 0.4 6.5 1.0 0.0 0.0 6.9 1.6 0.3 0.5 0.0 0.0 0.1 0.0 0.3 0.2 5.6 1.1 0.0 0.0 0.0 0.0 0.5 0.0 10.0 1.1 0.0 0.0 0.3 0.1 0.0 1.8 5.4 1.0 0.0 0.2 0.0 0.0 0.1 0.0 1.2 0.0 0.4 0.1 1.3 0.0 0.1 0.0 0.0 0.3 1.5 0.9 0.7 1.6 0.0 0.4 1.5 0.2 0.6 0.0 DNAAF1 "CILD13, DAU1, FLJ25330, LRRC50, ODA7, swt" ENSG00000154099 "Dynein axonemal assembly factor 1" Q8NEP3 16 84145287-84178767 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 22.7;testis: 45.3" "Cell type enhanced" "Detected in many" "Early spermatids: 116.2;Endometrial ciliated cells: 311.3;Plasma cells: 225.4;Respiratory ciliated cells: 494.5;Spermatocytes: 116.2" "Cancer enriched" "Detected in many" 5 "endometrial cancer: 3.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.3" "Group enriched" "Detected in many" 4 "granulocytes: 2.3;T-cells: 1.0" "Cell line enhanced" "Detected in some" "Hep G2: 1.7;Karpas-707: 4.9;PC-3: 1.4;SK-BR-3: 1.4;U-266/70: 4.0;U-266/84: 2.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA041166, HPA074239" Enhanced Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane, Cytosol" "Nuclear speckles" "HPA041166: AB_10794190, HPA074239: AB_2732250" "unprognostic (5.25e-3)" "unprognostic (2.40e-2)" "unprognostic (2.77e-2)" "prognostic favorable (2.14e-4)" "unprognostic (1.42e-1)" "unprognostic (9.99e-2)" "unprognostic (1.25e-1)" "unprognostic (4.48e-2)" "unprognostic (7.71e-2)" "unprognostic (1.58e-1)" "unprognostic (3.31e-5)" "unprognostic (2.70e-2)" "unprognostic (4.61e-3)" "unprognostic (1.77e-1)" "unprognostic (1.56e-1)" "unprognostic (1.27e-4)" "unprognostic (7.51e-4)" 0.3 0.7 1.4 0.1 1.2 1.2 0.3 1.1 1.9 2.2 9.7 0.3 0.0 0.5 1.4 0.4 22.7 0.0 0.4 1.6 1.5 1.0 0.8 3.5 0.0 4.1 7.3 0.4 0.3 0.3 2.4 0.2 4.3 0.2 0.0 0.4 0.1 0.2 0.2 0.1 0.1 0.0 3.0 0.7 0.2 45.3 1.6 0.0 1.6 0.0 0.0 0.4 0.0 1.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 1.4 0.0 0.1 0.5 0.0 0.0 0.2 0.0 0.0 0.0 4.0 2.8 0.4 0.1 0.0 0.0 1.3 0.2 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 2.3 0.3 0.1 0.4 1.0 0.3 1.4 1.2 1.1 1.9 1.6 1.5 4.1 7.3 4.3 3.0 1.6 1.3 1.1 0.0 12.4 1.6 5.7 0.6 1.5 9.6 0.0 1.4 4.5 1.5 0.7 1.5 67.2 3.7 54.2 0.2 0.5 0.1 0.0 1.3 116.2 311.3 4.4 1.9 0.0 0.0 9.6 0.4 0.4 2.4 0.5 14.6 3.8 2.6 2.2 0.6 1.9 0.0 5.2 0.0 18.3 7.0 1.5 26.7 1.2 21.6 87.2 0.0 0.8 2.4 1.0 0.5 0.6 0.9 0.0 0.4 225.4 1.4 0.0 1.7 494.5 51.0 0.0 1.6 7.3 116.2 17.0 0.2 0.3 0.4 4.5 1.2 0.3 0.9 DNMT3L MGC1090 ENSG00000142182 "DNA methyltransferase 3 like" Q9UJW3 21 44246339-44262216 "Metabolic proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "liver: 1.9" "Group enriched" "Detected in some" 6 "Hepatocytes: 20.8;Proximal tubular cells: 29.1" "Cancer enriched" "Detected in some" 90 "testis cancer: 46.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "BEWO: 24.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA055234, HPA066780" Approved Approved "Nuclear speckles" NA NA "Cluster 15: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles" "HPA055234: AB_2682750, HPA066780: AB_2685719" "unprognostic (1.05e-4)" "unprognostic (1.91e-1)" "unprognostic (2.73e-9)" "unprognostic (2.77e-1)" "unprognostic (5.28e-2)" 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.6 1.9 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 24.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 3.7 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 20.8 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 29.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.1 DPCD "DKFZP566F084, RP11-529I10.4" ENSG00000166171 "Deleted in primary ciliary dyskinesia homolog (mouse)" Q9BVM2 10 101570560-101609662 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 132.4" "Group enriched" "Detected in many" 4 "Early spermatids: 579.4;Late spermatids: 1068.7;Respiratory ciliated cells: 329.7;Spermatocytes: 313.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 20.2;intermediate monocyte: 22.2;myeloid DC: 29.6;non-classical monocyte: 9.5" "Group enriched" "Detected in all" 14 "dendritic cells: 29.6;monocytes: 22.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036603, HPA036604" Enhanced Approved "Nuclear speckles" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Nuclear speckles" "HPA036603: AB_2675212, HPA036604: AB_10673503" "unprognostic (1.22e-2)" "unprognostic (1.73e-3)" "unprognostic (4.66e-1)" "prognostic favorable (6.57e-4)" "unprognostic (1.90e-1)" "unprognostic (9.13e-2)" "unprognostic (4.00e-3)" "unprognostic (1.71e-1)" "unprognostic (1.67e-1)" "unprognostic (1.09e-1)" "unprognostic (1.08e-1)" "unprognostic (1.64e-1)" "unprognostic (4.55e-2)" "unprognostic (2.70e-1)" "unprognostic (5.04e-2)" "unprognostic (3.83e-2)" "unprognostic (7.54e-2)" 10.5 18.7 35.1 8.7 37.2 11.8 19.4 31.5 42.0 21.8 55.1 17.3 6.8 16.7 41.3 20.4 73.3 15.5 29.6 37.4 39.1 30.9 10.4 14.0 6.2 36.2 37.1 23.5 14.7 49.3 49.5 10.6 36.5 16.1 13.5 55.8 21.2 15.7 19.2 13.2 7.1 18.0 33.3 4.5 14.4 132.4 39.7 6.6 33.0 18.3 8.2 14.4 14.9 33.4 97.1 53.4 37.9 77.2 35.2 61.7 15.6 44.5 53.6 59.4 55.1 38.8 51.4 9.0 74.6 42.7 25.2 54.0 55.4 65.3 61.2 23.0 57.5 11.3 49.8 56.7 20.3 58.8 8.1 42.3 54.8 72.0 56.1 153.7 50.8 14.0 32.4 12.6 45.1 122.9 0.0 48.1 28.7 26.9 41.6 0.0 51.8 20.5 92.6 25.3 37.1 63.3 36.5 23.4 31.3 34.1 71.2 23.9 35.5 27.3 24.9 55.7 62.3 37.9 45.9 16.9 94.7 13.7 11.7 0.0 20.2 1.0 1.8 22.2 1.7 1.3 1.4 1.4 29.6 0.7 1.5 1.8 0.9 1.6 9.5 4.1 0.6 8.1 35.1 37.2 31.5 42.0 37.4 39.1 36.2 37.1 36.5 33.3 39.7 33.4 6.9 35.3 12.4 4.9 2.1 9.7 29.5 89.2 9.6 16.4 25.4 29.5 33.7 30.0 56.6 49.7 18.8 24.6 0.9 10.5 95.9 63.3 579.4 136.5 23.5 11.1 23.9 14.1 7.7 27.5 16.7 21.2 10.2 20.2 1.3 19.2 11.4 10.9 24.0 11.8 6.2 12.5 52.9 4.4 14.6 1068.7 23.6 8.7 16.0 3.7 6.9 27.8 2.1 4.0 1.4 33.9 12.4 27.8 5.6 18.6 3.5 117.3 329.7 49.1 0.0 12.4 29.0 313.8 77.4 8.7 14.2 10.7 2.9 25.3 22.1 23.9 DRP2 ENSG00000102385 "Dystrophin related protein 2" Q13474 X 101219769-101264502 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.8;lymphoid tissue: 4.7" "Group enriched" "Detected in some" 6 "Excitatory neurons: 35.6;Inhibitory neurons: 24.5;Oligodendrocyte precursor cells: 11.1" "Cancer enhanced" "Detected in single" "glioma: 1.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RH-30: 10.7;TIME: 18.5;U-87 MG: 4.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 56.0" HPA002949 Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear speckles, Plasma membrane" "HPA002949: AB_1078706" "unprognostic (8.47e-4)" "unprognostic (3.56e-3)" "unprognostic (1.01e-2)" "unprognostic (5.58e-4)" "unprognostic (1.74e-2)" "unprognostic (2.47e-2)" "unprognostic (7.93e-3)" "unprognostic (2.94e-3)" "unprognostic (1.27e-2)" "unprognostic (5.46e-3)" "unprognostic (1.42e-1)" "unprognostic (4.61e-2)" "unprognostic (4.44e-16)" "unprognostic (3.71e-4)" "unprognostic (4.22e-1)" "unprognostic (9.03e-2)" "unprognostic (1.25e-1)" 0.7 0.3 4.0 0.2 5.9 0.2 0.4 0.0 8.8 0.6 0.0 3.2 0.2 0.7 0.7 0.2 0.2 0.2 0.2 6.2 0.7 0.0 0.0 0.0 0.0 0.1 2.6 1.4 0.0 0.0 2.3 0.0 0.6 1.3 0.4 1.0 0.6 0.9 0.2 0.3 0.8 0.6 0.0 0.0 0.3 0.5 0.7 4.7 0.0 1.1 0.0 0.6 1.1 4.8 0.0 0.6 2.2 0.1 0.1 0.2 0.1 0.4 0.1 0.3 0.9 0.0 0.4 0.3 0.2 0.1 0.6 0.0 0.3 0.0 0.7 0.1 0.2 0.2 0.6 0.0 0.2 0.1 0.4 1.4 0.0 0.7 0.0 0.0 1.4 0.5 0.0 0.9 1.5 0.0 1.3 0.5 0.1 0.1 0.1 0.3 10.7 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.0 0.4 0.0 0.1 18.5 0.2 0.7 0.2 0.4 0.0 0.1 0.0 4.4 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 5.9 0.0 8.8 6.2 0.7 0.1 2.6 0.6 0.0 0.7 4.8 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.0 0.0 3.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 1.8 0.0 35.6 0.0 0.1 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 24.5 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.0 0.0 0.3 0.0 11.1 1.4 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 DUSP28 "DUSP26, VHP" ENSG00000188542 "Dual specificity phosphatase 28" Q4G0W2 2 240560054-240565256 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 39.7;Spermatocytes: 45.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 8.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 8.9" "Cell line enhanced" "Detected in many" "U-266/70: 8.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047456, CAB069448" Uncertain Uncertain "Nuclear speckles,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nuclear speckles" Cytosol "CAB069448: , HPA047456: AB_10961145" "unprognostic (1.88e-2)" "unprognostic (9.29e-2)" "unprognostic (4.86e-2)" "unprognostic (2.32e-1)" "unprognostic (1.65e-1)" "unprognostic (1.07e-2)" "unprognostic (1.09e-2)" "unprognostic (7.56e-3)" "unprognostic (4.13e-3)" "unprognostic (3.71e-2)" "prognostic favorable (1.84e-4)" "unprognostic (9.85e-2)" "unprognostic (1.80e-3)" "unprognostic (6.99e-2)" "unprognostic (2.52e-1)" "unprognostic (2.59e-1)" "unprognostic (2.10e-3)" 1.5 2.4 1.6 1.3 1.7 5.4 1.7 3.0 1.8 2.2 0.5 2.5 1.1 2.1 1.7 3.1 2.6 0.8 3.4 1.3 1.7 3.2 3.2 2.2 1.9 1.7 1.2 2.2 3.0 0.9 3.9 0.6 1.4 3.5 1.0 1.2 2.8 0.8 9.8 2.0 3.6 0.6 1.1 4.7 2.7 6.2 1.5 1.1 3.5 4.0 1.5 2.3 2.2 2.0 1.0 0.8 1.1 1.4 0.7 0.4 1.3 1.0 0.6 0.8 0.5 0.5 2.4 1.7 0.6 0.6 1.3 3.1 0.9 0.3 0.7 2.2 4.0 2.1 2.2 1.3 0.5 1.6 3.7 1.0 0.9 0.6 0.6 1.6 0.4 2.3 1.6 1.9 0.7 1.1 1.7 2.5 0.9 1.4 0.9 2.3 2.4 2.1 0.6 1.6 2.8 1.5 0.9 1.1 1.3 0.7 1.2 2.2 1.0 1.9 1.6 1.3 1.0 8.2 2.1 2.8 1.2 1.0 1.5 8.9 1.1 0.5 1.2 0.7 1.4 1.0 1.2 1.3 0.6 1.8 1.4 1.2 1.9 1.5 0.7 1.9 0.9 0.9 1.6 1.7 3.0 1.8 1.3 1.7 1.7 1.2 1.4 1.1 1.5 2.0 5.7 0.0 4.5 1.3 11.4 3.7 7.7 4.7 6.2 6.7 12.3 10.0 13.8 10.0 3.8 12.9 4.2 7.8 18.4 11.0 15.6 5.1 35.2 11.2 5.5 4.1 8.4 8.8 3.8 5.8 4.8 4.3 14.8 10.2 7.0 6.2 3.3 8.6 11.5 8.4 4.9 9.8 6.1 10.0 6.1 39.7 3.1 13.6 7.2 1.9 10.5 9.9 23.7 2.5 3.6 4.4 10.4 1.5 16.8 8.0 15.7 15.6 11.7 6.8 6.6 4.1 7.2 45.8 18.7 10.7 5.4 7.0 14.9 7.6 11.2 8.7 E2F3 ENSG00000112242 "E2F transcription factor 3" O00716 6 20401879-20493714 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 67.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029779, HPA065012" Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Nuclear speckles" Cytosol "HPA029779: AB_2732448, HPA065012: AB_2685403" "unprognostic (4.10e-2)" "unprognostic (1.15e-1)" "unprognostic (1.06e-1)" "unprognostic (1.80e-3)" "unprognostic (2.96e-1)" "unprognostic (9.14e-2)" "unprognostic (8.99e-3)" "unprognostic (9.13e-2)" "unprognostic (1.10e-1)" "prognostic favorable (1.69e-4)" "unprognostic (1.14e-2)" "unprognostic (5.64e-2)" "prognostic unfavorable (1.63e-8)" "unprognostic (1.23e-1)" "unprognostic (2.16e-1)" "unprognostic (3.50e-1)" "unprognostic (5.99e-3)" 6.5 4.9 4.8 9.8 5.2 19.8 4.1 2.8 5.7 3.3 3.0 5.4 5.2 3.6 3.9 4.9 2.5 6.4 5.1 6.4 4.6 5.8 4.4 4.9 11.0 3.7 4.6 1.4 2.1 3.1 1.8 5.6 4.2 3.3 6.3 6.1 2.7 3.1 10.0 2.6 5.7 6.0 3.7 8.4 3.6 3.4 5.5 8.6 8.5 9.3 9.5 8.5 2.7 3.8 14.3 11.6 32.2 35.1 10.9 11.9 22.0 18.9 16.8 18.2 19.9 14.3 8.8 32.3 35.2 18.2 16.9 14.6 37.8 17.4 30.3 12.2 25.3 58.1 20.4 16.3 11.6 38.6 33.0 9.7 12.6 17.7 21.6 18.8 12.7 29.8 65.3 19.4 20.9 15.0 43.6 43.2 24.2 11.0 11.9 46.5 27.8 36.5 21.8 25.1 22.9 42.2 17.3 24.1 26.3 20.0 12.4 23.4 17.2 28.6 17.4 14.2 30.5 12.1 40.1 38.3 7.1 23.2 41.3 5.6 2.3 1.1 1.6 1.6 2.0 0.4 1.0 2.4 2.6 0.4 0.8 1.8 7.2 3.5 1.1 1.1 1.6 1.1 4.8 5.2 2.8 5.7 6.4 4.6 3.7 4.6 4.2 3.7 5.5 3.8 4.8 0.0 2.6 53.8 10.6 9.2 12.3 7.0 7.4 34.1 11.9 7.2 10.6 4.3 10.6 7.3 22.9 8.3 15.0 12.0 9.8 7.6 12.2 3.9 14.1 8.5 12.0 17.2 67.7 6.9 13.8 9.2 12.8 10.6 20.3 32.3 14.6 4.7 17.1 32.0 31.9 11.7 4.1 47.2 17.7 5.7 2.8 28.7 5.4 27.2 23.8 2.9 15.5 37.7 2.9 14.8 10.3 3.0 19.1 22.1 4.5 25.1 2.2 9.0 0.0 9.0 11.5 3.0 4.7 16.5 8.9 3.1 15.3 5.7 13.8 18.4 E2F7 ENSG00000165891 "E2F transcription factor 7" Q96AV8 12 77021248-77065569 "Predicted intracellular proteins, Transcription factors" "Cell cycle, DNA damage, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.0;lymphoid tissue: 8.3" "Cell type enhanced" "Detected in many" "Early spermatids: 46.9;Endometrial ciliated cells: 17.2;Late spermatids: 70.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.7" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "midbrain: 5.8;pons: 6.4;thalamus: 11.3" HPA064866 Supported "Nuclear speckles" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" "Nuclear speckles" "HPA064866: AB_2685374" "unprognostic (1.21e-1)" "unprognostic (8.92e-2)" "unprognostic (7.39e-2)" "unprognostic (7.27e-2)" "unprognostic (1.54e-1)" "unprognostic (3.80e-2)" "unprognostic (6.14e-5)" "unprognostic (1.05e-3)" "unprognostic (1.72e-1)" "unprognostic (3.57e-2)" "unprognostic (5.67e-5)" "unprognostic (1.42e-1)" "unprognostic (0.00e+0)" "unprognostic (3.05e-2)" "unprognostic (1.57e-1)" "unprognostic (1.00e-1)" "unprognostic (2.51e-1)" 0.2 0.1 0.2 1.1 0.2 5.0 0.2 0.0 0.3 0.3 0.3 0.9 0.7 0.2 0.0 1.4 0.6 0.7 0.2 0.2 0.2 0.1 0.2 0.3 1.5 0.7 0.8 0.1 0.2 0.1 0.5 1.0 0.4 0.2 1.5 0.2 0.2 0.1 0.0 1.1 0.8 0.3 0.6 0.3 0.6 2.9 0.2 8.3 0.1 0.1 1.6 0.6 0.5 0.2 20.1 9.4 25.7 10.1 0.8 2.5 31.1 27.6 29.8 14.2 17.0 12.8 6.6 11.2 5.4 5.5 29.5 15.1 15.5 29.8 27.1 4.4 10.4 9.8 27.3 7.3 5.9 8.5 8.8 0.8 7.7 37.4 22.9 8.3 14.2 19.0 10.4 8.9 29.5 10.1 31.9 0.1 18.1 6.7 21.9 23.0 22.2 6.2 3.5 16.8 16.3 10.7 22.9 7.9 6.5 10.9 12.6 8.7 39.3 53.5 26.8 23.0 36.7 9.5 5.8 7.1 19.3 3.8 34.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.7 0.4 0.0 0.2 0.2 0.0 0.3 0.2 0.2 0.7 0.8 0.4 0.6 0.2 0.2 0.1 0.0 0.5 2.3 0.5 0.3 1.0 1.4 4.6 0.0 0.6 0.9 2.1 0.0 2.2 0.0 0.0 1.8 0.4 1.5 0.0 0.3 46.9 17.2 0.8 1.5 0.0 7.4 0.4 1.1 3.1 0.8 6.1 3.1 4.5 6.3 0.0 0.0 0.9 0.0 0.2 1.2 2.0 0.3 1.2 70.2 0.3 1.3 0.0 3.7 0.0 1.6 0.0 0.5 0.0 12.0 0.1 0.7 6.9 1.7 0.0 0.0 3.1 0.1 0.0 0.0 1.2 1.2 2.1 6.3 0.6 0.3 0.8 0.4 2.1 4.3 EEPD1 KIAA1706 ENSG00000122547 "Endonuclease/exonuclease/phosphatase family domain containing 1" Q7L9B9 7 36153254-36301538 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 46.9" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 88.0;Oligodendrocytes: 175.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 51.8;neutrophil: 46.4" "Group enriched" "Detected in many" 6 "granulocytes: 51.8;T-cells: 23.0" "Cell line enhanced" "Detected in many" "HDLM-2: 18.3;PC-3: 22.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053668 Approved "Nuclear speckles,Vesicles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear speckles" Vesicles "HPA053668: AB_2682223" "unprognostic (1.30e-1)" "unprognostic (1.19e-1)" "unprognostic (1.54e-3)" "unprognostic (5.21e-3)" "unprognostic (1.14e-1)" "unprognostic (4.76e-1)" "unprognostic (1.19e-2)" "unprognostic (3.75e-2)" "unprognostic (7.89e-2)" "unprognostic (8.77e-2)" "unprognostic (7.74e-2)" "unprognostic (2.62e-1)" "unprognostic (2.82e-1)" "unprognostic (1.07e-2)" "unprognostic (6.52e-2)" "unprognostic (2.23e-2)" "unprognostic (4.59e-2)" 19.5 5.2 9.8 4.0 12.5 8.1 18.3 10.6 14.2 10.2 7.3 12.0 9.9 7.7 3.6 7.1 7.3 11.7 11.1 10.4 10.6 5.9 24.0 8.1 4.6 12.0 12.8 8.5 11.5 2.2 4.4 4.0 12.7 12.5 3.8 1.5 4.1 3.4 46.9 12.8 11.5 5.6 10.3 10.8 17.0 5.3 13.0 12.8 3.1 12.8 3.0 10.9 9.1 19.2 2.2 5.9 1.8 5.6 16.2 3.5 0.1 1.5 7.2 1.1 2.0 1.2 4.5 5.9 1.8 2.2 16.8 2.4 2.4 2.8 1.0 18.3 4.0 0.7 0.5 11.0 1.5 0.9 5.5 7.3 1.7 0.7 0.4 4.5 0.1 4.4 7.3 0.6 1.2 2.3 6.1 14.6 8.2 7.4 22.4 1.6 2.0 1.3 3.6 4.7 4.4 3.1 0.5 0.8 2.2 3.2 1.8 7.0 0.5 2.2 6.5 1.5 1.7 4.3 5.1 0.0 5.4 3.8 1.4 23.1 5.9 51.8 3.0 3.6 5.2 0.3 23.0 6.6 3.2 0.0 5.0 1.5 46.4 3.9 1.6 2.9 11.6 4.2 9.8 12.5 10.6 14.2 10.4 10.6 12.0 12.8 12.7 10.3 13.0 19.2 32.4 0.0 0.5 30.0 1.3 2.7 14.7 1.8 1.8 4.2 4.9 7.2 4.0 34.3 2.1 0.0 20.9 0.2 0.9 10.8 5.9 26.2 17.4 8.4 3.0 14.8 9.6 1.3 28.4 7.4 0.3 4.0 20.9 7.2 8.9 0.9 3.9 16.9 25.3 6.7 88.0 6.2 0.0 5.8 5.5 3.6 5.0 9.8 3.6 45.0 3.8 2.0 0.0 1.5 175.4 16.9 12.6 16.6 0.7 8.7 19.4 1.9 2.6 1.4 6.6 2.1 6.6 0.7 5.4 4.2 4.0 0.5 3.3 6.4 6.2 10.2 EFCAB13 "C17orf57, FLJ40342" ENSG00000178852 "EF-hand calcium binding domain 13" Q8IY85 17 47323290-47441312 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "testis: 20.5" "Group enriched" "Detected in many" 4 "Early spermatids: 169.8;Late spermatids: 185.7;Spermatocytes: 64.1" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002501, HPA021633, HPA023249, HPA026561" Uncertain Enhanced "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Cytosol" "Nuclear speckles" "CAB002501: AB_564092, HPA021633: AB_1845594, HPA023249: AB_1845595, HPA026561: AB_1845596" "unprognostic (1.66e-1)" "unprognostic (3.48e-1)" "unprognostic (1.24e-2)" "unprognostic (2.40e-2)" "unprognostic (6.71e-2)" "unprognostic (3.04e-2)" "unprognostic (3.04e-1)" "unprognostic (1.40e-1)" "unprognostic (7.43e-2)" "unprognostic (8.79e-3)" "unprognostic (8.75e-2)" "unprognostic (1.75e-2)" "unprognostic (1.46e-5)" "unprognostic (1.68e-1)" "unprognostic (1.61e-1)" "unprognostic (8.10e-2)" "unprognostic (1.90e-3)" 3.2 2.6 1.3 3.2 2.3 3.9 4.2 3.7 2.0 3.8 0.9 2.9 4.8 6.0 4.0 1.6 3.5 2.9 2.5 1.1 2.9 5.4 3.5 3.1 4.5 2.9 2.5 3.8 1.8 3.2 2.5 3.6 3.3 2.7 3.3 3.9 2.3 1.9 0.8 2.2 3.3 2.4 1.7 4.4 3.6 20.5 2.8 1.8 14.2 0.4 3.2 2.6 2.4 4.3 0.9 3.7 1.5 0.2 1.8 6.4 2.8 2.1 0.4 0.6 1.0 1.7 5.2 0.3 5.8 0.7 0.0 1.0 0.0 0.4 3.5 0.1 0.5 4.9 3.4 0.5 1.8 3.8 0.5 1.2 1.7 2.4 0.0 4.4 4.1 3.8 1.5 9.0 2.2 0.1 1.7 2.1 0.8 2.6 2.9 4.5 1.1 1.8 8.3 3.0 1.1 0.5 1.1 0.1 2.5 1.1 6.0 4.5 1.5 0.2 1.1 0.3 1.0 9.4 6.9 0.9 5.5 7.3 3.8 2.8 1.0 0.3 0.5 0.6 0.4 2.2 0.4 0.3 0.5 2.6 1.2 0.7 0.0 0.5 0.4 0.3 0.1 0.3 1.3 2.3 3.7 2.0 1.1 2.9 2.9 2.5 3.3 1.7 2.8 4.3 5.3 9.6 2.2 7.2 7.9 0.8 1.8 0.9 0.6 2.5 2.3 2.4 6.2 1.5 1.3 0.0 0.0 0.3 1.3 0.4 0.0 1.0 169.8 1.9 2.5 6.0 3.0 1.3 8.0 0.9 0.1 4.1 2.6 5.4 6.3 1.3 4.6 0.5 1.9 3.3 10.1 0.4 2.0 2.9 2.0 185.7 1.8 2.6 0.0 32.8 2.7 1.0 0.0 13.0 19.5 1.1 0.3 3.8 1.4 1.1 1.2 1.6 3.3 2.9 0.0 3.2 4.0 64.1 24.5 0.0 0.6 0.0 2.3 1.2 0.7 1.3 EGFL8 "C6orf8, NG3" ENSG00000241404 "EGF like domain multiple 8" Q99944 6 32164595-32168281 "Metabolic proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 6.4;Granulosa cells: 10.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 3.2;SK-MEL-30: 3.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA061173 Uncertain Approved "Nuclear speckles,Vesicles" "Secreted - unknown location" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 40: Granulosa cells - Unknown function" Vesicles "Nuclear speckles" "HPA061173: AB_2684443" "unprognostic (7.13e-2)" "unprognostic (1.86e-1)" "unprognostic (6.79e-3)" "unprognostic (3.64e-1)" "unprognostic (1.30e-1)" "unprognostic (7.60e-4)" "unprognostic (3.42e-2)" "unprognostic (2.49e-1)" "unprognostic (6.42e-3)" "unprognostic (1.97e-1)" "unprognostic (7.60e-3)" "unprognostic (8.11e-3)" "unprognostic (1.07e-4)" "unprognostic (1.11e-1)" "unprognostic (6.79e-2)" "unprognostic (1.21e-1)" "unprognostic (3.29e-2)" 13.3 7.2 3.8 0.5 3.5 1.1 13.6 3.6 5.7 23.4 4.1 19.8 0.6 10.0 0.8 12.3 16.3 3.0 14.2 3.9 3.9 16.3 7.4 9.4 0.3 3.8 3.9 31.2 5.1 0.4 8.2 2.9 3.7 16.9 0.5 0.0 7.9 1.4 3.8 12.8 8.8 0.3 3.8 7.9 10.2 4.4 4.1 0.6 8.7 2.5 0.2 13.5 17.2 3.8 0.2 0.1 0.4 1.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 1.1 0.4 0.0 0.0 0.0 0.5 0.0 0.3 3.2 0.0 0.0 0.3 0.0 0.4 0.2 0.1 0.0 0.2 0.7 0.5 0.0 0.0 0.6 1.0 1.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.6 0.0 0.0 3.4 0.0 1.0 0.7 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 3.5 3.6 5.7 3.9 3.9 3.8 3.9 3.7 3.8 4.1 3.8 1.2 6.4 4.1 0.0 0.3 1.5 0.6 0.3 4.6 1.5 0.5 0.3 0.1 0.0 1.6 1.8 2.1 0.8 0.6 0.2 0.0 0.4 0.1 1.0 1.9 1.7 0.0 1.7 0.0 0.2 0.4 1.5 4.6 1.3 0.0 10.4 3.3 0.3 0.2 0.0 0.0 1.1 0.0 0.6 1.6 0.2 3.7 0.7 0.0 0.0 0.0 0.9 3.1 0.0 0.0 0.3 0.2 1.2 2.1 0.7 0.4 0.1 1.6 1.5 0.0 2.0 1.5 0.5 0.4 4.0 2.3 0.8 0.9 1.5 1.3 0.5 EHMT2 "BAT8, C6orf30, Em:AF134726.3, G9A, KMT1C, NG36/G9a" ENSG00000204371 "Euchromatic histone lysine methyltransferase 2" Q96KQ7 6 31879759-31897687 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Chromatin regulator, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HL-60: 13.3;NTERA-2: 19.3;U-266/84: 16.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050550, HPA060259" Supported Supported "Nucleoplasm,Nuclear speckles" "Intracellular and membrane" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 5: NTERA-2 - Transcription" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" Nucleoplasm "HPA050550: AB_2681170, HPA060259: AB_2684234" "unprognostic (3.11e-2)" "unprognostic (2.72e-1)" "unprognostic (4.39e-2)" "unprognostic (1.92e-2)" "unprognostic (5.44e-2)" "unprognostic (3.51e-2)" "prognostic unfavorable (1.79e-4)" "unprognostic (3.55e-2)" "unprognostic (7.41e-2)" "unprognostic (1.01e-1)" "unprognostic (5.89e-2)" "unprognostic (1.88e-1)" "unprognostic (9.78e-3)" "unprognostic (8.72e-2)" "unprognostic (1.84e-1)" "unprognostic (2.25e-1)" "unprognostic (9.03e-2)" 8.6 9.6 0.5 0.3 0.4 1.0 8.7 0.4 0.5 15.1 0.2 12.9 2.4 19.8 1.7 10.1 12.8 0.0 5.7 0.4 0.4 7.1 4.6 7.3 1.0 0.4 0.5 16.1 7.8 0.6 12.8 0.7 0.4 10.3 0.3 0.6 9.5 1.3 5.5 9.3 10.5 1.4 0.4 11.5 9.4 12.6 0.5 1.5 10.3 0.4 1.0 13.1 11.3 0.4 0.0 4.5 7.8 0.0 3.4 1.8 5.0 3.5 2.8 3.9 3.2 0.0 0.0 0.0 7.6 5.7 4.0 0.0 0.0 8.6 1.8 5.4 11.8 0.0 0.0 0.1 0.0 13.3 0.0 4.6 1.4 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 9.4 0.0 19.3 0.0 0.0 8.8 0.0 0.0 1.5 0.0 0.0 0.0 0.0 2.3 6.5 3.1 0.0 0.0 3.8 4.1 3.1 6.9 0.0 11.0 16.1 3.8 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.5 0.4 0.4 0.5 0.4 0.4 0.4 0.5 0.4 0.4 0.5 0.4 16.9 16.0 12.0 22.9 20.3 8.4 6.3 11.9 26.2 60.6 15.9 17.8 6.6 17.2 18.9 25.8 41.7 24.6 13.4 9.2 7.9 15.7 41.5 10.1 19.1 16.1 22.6 19.3 16.6 12.2 15.0 16.0 13.3 11.8 14.5 33.8 22.1 7.5 16.3 38.7 24.4 16.4 12.2 12.9 7.3 60.0 27.4 12.1 19.6 9.4 19.9 26.8 25.7 20.1 23.9 10.8 9.1 23.0 16.5 6.2 12.5 10.1 10.8 48.2 26.3 16.3 15.0 20.8 33.7 23.5 11.1 5.6 18.3 19.9 19.0 5.2 ELOA "SIII, TCEB3, TCEB3A" ENSG00000011007 "Elongin A" Q14241 1 23743155-23762059 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 83.9;Ductal cells: 41.3;Syncytiotrophoblasts: 41.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005910 Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 18: U-2197 - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Nuclear speckles" Cytosol "HPA005910: AB_1080227" "unprognostic (6.90e-2)" "unprognostic (5.99e-3)" "unprognostic (4.08e-2)" "unprognostic (1.44e-1)" "unprognostic (1.99e-1)" "unprognostic (3.93e-2)" "prognostic unfavorable (1.44e-5)" "unprognostic (1.72e-1)" "unprognostic (8.84e-3)" "unprognostic (6.00e-2)" "unprognostic (4.94e-2)" "unprognostic (2.14e-2)" "unprognostic (2.95e-3)" "unprognostic (2.90e-1)" "unprognostic (4.27e-2)" "unprognostic (4.80e-2)" "unprognostic (4.14e-2)" 25.7 12.7 9.8 18.8 10.8 33.4 16.5 13.0 11.5 15.7 10.4 14.8 12.6 13.3 10.1 23.8 12.9 15.4 15.5 10.1 10.9 14.4 29.6 25.8 17.7 10.9 10.6 16.1 42.4 27.0 11.5 19.2 11.0 14.9 16.5 12.7 17.4 13.3 33.2 20.1 13.9 16.8 9.7 16.2 26.5 18.9 11.1 21.6 21.3 26.4 23.6 24.5 14.6 11.8 52.0 28.3 40.2 34.6 46.2 28.6 25.3 52.4 46.9 76.2 66.1 34.9 44.1 27.0 62.7 53.3 42.8 48.5 83.0 55.2 84.4 77.8 41.1 60.9 42.2 41.1 40.9 64.7 35.3 30.6 43.6 83.3 63.2 28.2 46.4 43.7 91.8 45.3 61.6 39.3 33.5 26.1 46.8 57.7 42.4 49.8 50.9 51.3 35.8 34.8 76.2 42.9 47.7 47.5 58.5 44.3 34.4 23.5 49.5 59.5 52.8 106.9 62.5 46.8 56.4 59.2 52.1 63.2 60.7 28.2 24.6 19.6 16.5 24.9 16.3 23.5 13.8 15.1 22.6 18.5 11.2 14.9 6.5 13.7 24.1 18.4 17.1 17.7 9.8 10.8 13.0 11.5 10.1 10.9 10.9 10.6 11.0 9.7 11.1 11.8 24.1 28.9 83.9 0.0 7.9 0.0 0.0 0.0 0.0 0.0 19.6 16.0 0.0 0.0 18.0 18.4 0.0 28.1 17.5 0.0 5.9 41.3 0.0 15.4 27.4 12.5 0.0 0.0 0.0 32.7 35.7 10.1 0.0 23.3 13.9 21.5 0.0 0.0 28.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 35.2 0.0 0.0 0.0 0.0 37.9 0.0 0.0 4.9 0.0 0.0 19.0 16.8 0.0 0.0 0.0 12.8 0.0 0.0 0.0 0.0 41.3 9.6 32.5 0.0 0.0 EPC2 DKFZP566F2124 ENSG00000135999 "Enhancer of polycomb homolog 2" Q52LR7 2 148644440-148787569 "Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 125.7;Oligodendrocytes: 99.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036759 Uncertain Approved "Nuclear speckles" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 36: HEL - Hemostasis" "Cluster 44: Endometrium - Transcription" "Nuclear speckles" "HPA036759: AB_10672365" "unprognostic (1.65e-1)" "unprognostic (1.24e-1)" "unprognostic (7.16e-2)" "unprognostic (2.83e-3)" "unprognostic (2.59e-2)" "unprognostic (1.98e-2)" "unprognostic (1.07e-2)" "unprognostic (1.47e-2)" "unprognostic (3.86e-2)" "unprognostic (2.29e-1)" "unprognostic (6.21e-2)" "unprognostic (5.72e-2)" "unprognostic (1.32e-2)" "unprognostic (1.54e-2)" "unprognostic (1.72e-1)" "unprognostic (1.76e-1)" "unprognostic (4.91e-2)" 16.4 14.0 9.6 13.5 10.9 50.3 17.2 22.0 13.4 18.2 7.8 12.4 9.7 25.5 14.1 12.2 15.3 15.3 15.5 9.9 11.3 12.9 12.7 14.6 18.0 9.6 9.9 31.9 9.8 12.1 9.9 18.5 9.9 16.2 13.9 14.0 11.5 15.5 15.9 11.7 10.5 19.1 9.7 15.9 12.0 14.2 11.5 23.1 19.3 18.5 15.9 15.6 14.0 14.5 9.2 7.0 23.8 14.8 15.7 19.5 17.9 15.9 21.4 25.3 21.2 14.1 12.0 19.8 7.8 18.7 10.9 12.1 20.7 12.7 31.1 17.6 15.4 38.9 11.0 19.8 16.0 29.7 22.7 20.5 22.1 25.8 25.3 15.6 15.9 15.9 20.9 33.4 16.0 14.7 20.2 19.8 24.3 8.7 13.6 20.7 22.1 18.2 12.7 25.6 32.5 23.6 19.6 12.0 29.8 16.6 7.7 25.8 19.2 20.2 17.7 14.0 13.6 20.3 17.0 25.0 16.0 17.4 21.9 0.1 0.9 1.2 0.9 0.7 1.3 0.8 1.4 0.8 0.9 0.8 1.5 1.1 4.5 0.3 2.0 1.0 1.4 0.5 9.6 10.9 22.0 13.4 9.9 11.3 9.6 9.9 9.9 9.7 11.5 14.5 24.2 25.6 13.6 60.1 21.1 14.0 26.4 4.8 4.0 19.6 15.4 17.1 22.0 8.6 15.1 9.2 6.2 11.3 27.5 8.4 3.9 9.1 28.5 23.5 25.9 17.0 18.0 15.8 79.2 8.8 11.7 20.7 8.6 27.3 6.3 15.6 7.9 5.0 8.6 8.4 75.3 9.2 2.0 16.1 10.2 5.5 23.9 17.7 12.4 70.3 11.3 14.1 20.6 125.7 99.3 9.3 9.1 23.0 10.7 20.3 6.3 6.7 9.8 15.7 13.1 44.4 25.4 19.3 18.6 7.8 15.6 20.1 25.2 16.3 8.1 23.6 EPG5 "hEPG5, KIAA1632" ENSG00000152223 "Ectopic P-granules autophagy protein 5 homolog" Q9HCE0 18 45847609-45967329 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Autophagy "Cataract, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 53.1;Oligodendrocytes: 51.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "LHCN-M2: 55.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031689 Uncertain Approved "Nuclear speckles" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear speckles" "HPA031689: AB_10609997" "unprognostic (3.43e-1)" "unprognostic (1.20e-1)" "unprognostic (8.11e-2)" "unprognostic (6.84e-2)" "unprognostic (2.20e-2)" "unprognostic (4.59e-2)" "unprognostic (5.58e-2)" "unprognostic (1.02e-1)" "unprognostic (4.66e-1)" "unprognostic (4.87e-1)" "unprognostic (1.15e-2)" "unprognostic (7.50e-2)" "prognostic favorable (4.04e-5)" "unprognostic (5.71e-2)" "unprognostic (1.35e-1)" "unprognostic (4.05e-1)" "unprognostic (1.18e-1)" 6.6 6.8 5.8 4.4 6.0 13.8 6.8 6.3 6.2 7.1 5.1 5.8 3.2 6.1 5.8 7.1 6.0 3.2 8.4 6.2 5.3 6.6 6.0 8.8 5.7 5.1 8.1 8.9 6.3 6.9 7.6 4.5 5.3 5.9 4.0 8.6 6.0 3.7 8.6 10.1 6.0 4.1 4.5 9.5 5.6 4.8 5.8 8.4 9.3 6.7 5.9 5.4 6.6 6.3 5.3 4.1 4.1 3.0 13.8 16.6 4.1 33.2 13.7 18.7 19.4 1.2 3.9 5.4 2.0 25.0 22.5 4.9 5.5 6.6 23.7 4.5 2.3 4.2 4.7 4.2 13.1 7.2 10.4 11.2 6.0 20.6 14.0 16.5 9.4 4.7 3.7 2.8 55.8 3.7 3.2 6.9 2.0 1.9 2.5 3.0 5.1 3.8 8.8 7.3 4.4 3.4 5.9 2.4 7.0 5.8 3.4 5.1 23.0 23.2 4.9 3.4 9.2 5.7 4.3 3.0 9.9 6.2 7.7 0.4 0.7 0.7 1.5 0.7 1.4 0.4 0.9 0.8 0.5 0.6 0.7 0.9 0.8 0.4 0.6 0.6 0.5 0.3 5.8 6.0 6.3 6.2 6.2 5.3 5.1 8.1 5.3 4.5 5.8 6.3 8.8 19.2 10.5 24.5 9.0 10.3 4.6 6.8 8.0 16.7 11.9 8.3 17.1 10.0 7.4 11.0 25.0 7.6 15.7 5.8 1.9 6.5 4.6 9.0 9.8 9.3 8.3 11.4 53.1 3.6 4.4 7.8 6.1 16.9 7.0 14.4 13.6 10.3 12.2 13.5 46.5 6.9 6.1 16.0 6.2 3.0 12.5 11.5 14.2 40.3 16.6 6.5 27.8 40.2 51.4 7.8 6.5 11.7 10.0 9.1 6.2 8.3 10.5 17.4 13.1 9.8 6.7 8.4 7.1 5.9 13.2 9.0 15.4 9.8 6.5 9.4 EPHA2 ECK ENSG00000142627 "EPH receptor A2" P29317 1 16124337-16156069 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, RAS pathway related proteins" "Angiogenesis, Apoptosis, Cell adhesion, Differentiation, Host-virus interaction" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cataract, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 147.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 202.3;Glandular and luminal cells: 182.9;Squamous epithelial cells: 156.3;Suprabasal keratinocytes: 248.3;Urothelial cells: 200.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 94 "plasmacytoid DC: 9.4" "Lineage enriched" "Detected in single" 94 "dendritic cells: 9.4" "Cell line enhanced" "Detected in many" "CAPAN-2: 201.1;PC-3: 229.0;U-251 MG: 242.1;WM-115: 258.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" CAB010464 Supported "Nuclear speckles,Golgi apparatus,Plasma membrane,Cell Junctions" NA Yes 12000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cell Junctions" "Nuclear speckles, Golgi apparatus" "CAB010464: AB_631436" "unprognostic (9.41e-2)" "unprognostic (1.67e-1)" "unprognostic (4.13e-2)" "unprognostic (1.67e-2)" "unprognostic (6.22e-2)" "unprognostic (9.12e-2)" "unprognostic (5.24e-2)" "unprognostic (1.29e-3)" "unprognostic (2.52e-2)" "unprognostic (7.05e-3)" "unprognostic (1.52e-3)" "unprognostic (2.77e-1)" "unprognostic (2.65e-2)" "unprognostic (2.08e-1)" "unprognostic (1.73e-1)" "unprognostic (4.77e-3)" "unprognostic (4.40e-2)" 21.4 9.5 3.5 4.8 3.1 0.3 14.6 2.9 3.7 38.2 11.7 12.4 10.0 12.1 1.3 147.9 13.5 28.2 15.8 3.1 3.1 18.7 18.9 17.9 7.6 3.8 3.7 5.8 23.2 3.7 7.4 14.0 3.8 11.2 5.8 6.4 67.7 4.2 4.6 40.3 12.8 3.7 3.6 7.6 15.6 1.8 4.3 3.2 15.2 5.1 11.1 56.1 58.8 3.1 76.9 151.7 41.4 20.1 2.9 3.5 24.3 45.2 63.4 79.9 50.6 63.9 201.1 0.1 189.8 25.9 98.8 30.6 9.9 104.4 27.6 0.4 7.0 0.0 46.7 41.1 51.3 0.1 0.2 4.8 38.1 43.7 95.6 125.0 86.4 0.0 0.3 0.1 51.6 24.3 0.0 0.0 20.0 57.2 229.0 0.1 37.6 0.2 85.1 39.0 0.1 6.4 87.8 21.2 6.1 21.3 3.0 0.9 108.1 28.5 76.7 2.0 242.1 0.0 0.5 0.6 22.0 0.1 258.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 3.5 3.1 2.9 3.7 3.1 3.1 3.8 3.7 3.8 3.6 4.3 3.1 17.1 54.5 38.4 2.0 1.2 202.3 114.3 110.9 66.0 2.7 39.5 43.9 6.5 44.3 113.4 9.2 4.2 9.7 8.9 96.8 0.0 33.8 5.8 104.5 19.2 26.3 3.0 0.0 0.1 14.2 1.2 5.8 68.3 182.9 5.7 0.4 29.3 23.3 1.9 0.0 0.2 42.0 34.6 1.6 17.0 0.2 3.4 3.7 26.6 4.7 1.1 7.1 0.0 0.0 0.0 104.6 111.7 0.0 0.0 60.8 22.4 1.8 89.8 2.5 32.9 11.6 21.2 0.2 0.8 156.3 248.3 7.5 2.6 0.4 42.9 200.4 EPHB6 HEP ENSG00000106123 "EPH receptor B6" 7 142855061-142871094 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 66.0;skin 1: 65.8" "Cell type enhanced" "Detected in many" "Muller glia cells: 226.6;Sertoli cells: 105.2;Suprabasal keratinocytes: 118.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 6 "MOLT-4: 39.6;RT4: 71.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035784 Uncertain "Nuclear speckles" "Intracellular and membrane" NA NA "Cluster 30: Non-specific - Translation" "Cluster 27: Brain & Skin - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 5: Muller glia cells - Visual perception" "Nuclear speckles" "HPA035784: AB_2674781" "unprognostic (1.90e-2)" "prognostic favorable (1.80e-4)" "unprognostic (7.08e-3)" "unprognostic (2.95e-2)" "prognostic unfavorable (4.10e-4)" "unprognostic (2.53e-3)" "unprognostic (3.15e-2)" "unprognostic (4.39e-1)" "unprognostic (1.78e-1)" "unprognostic (4.69e-2)" "unprognostic (1.06e-3)" "unprognostic (3.18e-1)" "unprognostic (1.69e-1)" "unprognostic (1.21e-1)" "unprognostic (4.93e-2)" "unprognostic (3.16e-1)" "prognostic favorable (4.68e-5)" 9.2 0.7 26.9 1.8 42.0 2.2 3.6 9.7 66.0 18.6 9.2 2.6 0.0 8.9 2.3 10.6 13.5 1.5 3.2 27.7 14.4 4.0 1.5 4.0 2.3 12.9 14.1 7.9 12.4 0.9 2.4 0.4 12.9 14.3 0.1 2.8 5.7 7.3 1.4 65.8 5.0 1.6 12.6 4.3 3.3 5.0 16.7 14.5 9.4 0.7 2.3 7.8 18.5 48.7 0.2 0.0 0.0 0.8 7.5 3.0 0.0 0.9 0.8 0.2 0.1 1.0 2.3 0.0 0.0 0.1 0.0 8.8 0.4 0.0 0.0 2.0 0.3 0.6 0.0 0.3 1.2 9.7 0.4 1.7 0.8 3.0 0.0 0.1 0.5 5.2 2.1 0.0 0.1 0.2 39.6 5.8 6.8 1.4 3.6 0.8 0.0 0.0 0.0 71.7 0.0 0.0 3.3 2.0 0.0 1.5 6.1 0.4 0.0 0.0 2.6 0.0 0.0 0.0 0.6 0.0 0.0 3.5 0.0 0.0 0.8 0.4 0.0 0.3 0.3 1.6 1.1 0.6 0.5 0.3 1.4 0.7 0.5 0.0 0.1 0.0 1.0 0.7 26.9 42.0 9.7 66.0 27.7 14.4 12.9 14.1 12.9 12.6 16.7 48.7 1.9 3.2 1.7 6.2 12.5 54.4 30.7 13.3 42.1 12.1 1.8 6.7 3.0 45.8 10.0 7.3 2.1 0.2 1.9 0.1 5.9 28.2 0.9 5.7 20.0 2.8 1.8 8.6 65.1 6.8 0.0 15.6 6.1 7.2 0.0 3.2 1.8 3.5 4.2 0.0 43.4 0.1 0.0 13.2 10.4 8.3 30.1 8.9 12.4 8.4 7.1 226.6 5.2 5.5 4.6 32.4 0.1 9.8 1.6 11.0 0.0 0.6 4.9 6.6 105.2 31.5 20.5 0.5 7.2 40.0 118.5 0.3 14.0 0.7 0.1 22.2 EPOR ENSG00000187266 "Erythropoietin receptor" P19235 19 11377207-11384342 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" Receptor "Cancer-related genes, Congenital erythrocytosis, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 114.7;Hepatic stellate cells: 66.8;Hofbauer cells: 42.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 20.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA077654 Supported "Nuclear speckles,Plasma membrane" "Intracellular and membrane" NA Yes "Cluster 14: Monocytes - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane" "Nuclear speckles" "HPA077654: " "unprognostic (9.13e-2)" "unprognostic (7.14e-2)" "unprognostic (1.45e-2)" "unprognostic (1.04e-1)" "unprognostic (1.88e-1)" "unprognostic (1.11e-1)" "unprognostic (3.70e-1)" "unprognostic (1.50e-2)" "unprognostic (5.60e-2)" "unprognostic (9.00e-2)" "prognostic favorable (3.17e-5)" "unprognostic (6.37e-3)" "unprognostic (1.59e-2)" "unprognostic (2.08e-1)" "unprognostic (2.00e-1)" "unprognostic (7.48e-2)" "unprognostic (1.01e-3)" 6.5 17.5 6.0 1.4 6.3 22.4 5.0 6.7 8.2 7.1 7.7 2.7 1.4 3.3 13.6 1.3 6.7 2.3 9.7 6.3 6.0 21.6 10.7 6.4 2.2 6.1 6.1 3.1 11.8 23.2 8.2 8.0 6.4 4.6 1.7 3.3 3.3 7.3 2.3 1.6 2.3 1.8 6.0 11.9 7.8 1.8 6.2 1.7 30.2 1.5 1.6 3.1 3.7 6.3 3.7 1.2 3.6 4.2 5.3 3.4 2.1 2.2 7.0 3.6 4.5 1.3 1.4 2.5 4.0 4.1 5.0 0.9 2.8 1.4 4.1 2.1 1.6 14.3 1.3 2.1 3.8 2.9 5.5 2.4 0.5 4.8 3.3 8.5 8.5 5.3 12.5 12.0 4.1 3.3 2.7 3.5 1.9 2.0 9.6 7.2 6.3 5.6 3.4 1.9 1.4 11.0 1.5 2.0 6.4 3.7 3.6 4.9 3.5 1.9 2.6 6.6 2.1 6.0 4.7 2.8 10.5 2.9 2.1 9.3 3.7 3.0 1.7 4.6 3.6 2.0 3.4 2.5 2.1 1.2 3.7 2.2 10.2 0.8 7.3 0.1 3.3 2.4 6.0 6.3 6.7 8.2 6.3 6.0 6.1 6.1 6.4 6.0 6.2 6.3 6.1 19.2 18.8 24.8 11.5 2.3 4.0 2.0 2.8 3.8 3.6 6.1 6.5 5.7 3.1 20.2 0.0 2.2 5.2 1.3 3.9 2.2 0.8 9.9 6.8 13.5 8.4 114.7 2.2 3.3 12.2 9.8 15.3 13.9 26.6 1.2 66.8 3.5 42.4 1.7 3.0 3.5 2.0 17.0 4.0 0.6 2.8 15.4 8.8 7.5 4.6 7.9 11.3 1.0 1.6 3.1 0.4 4.1 3.8 1.8 0.2 1.0 2.9 2.5 19.7 3.8 18.5 5.1 7.7 1.6 1.0 3.0 9.6 2.6 1.8 1.2 ERBIN "ERBB2IP, LAP2" ENSG00000112851 "Erbb2 interacting protein" Q96RT1 5 65926556-66082546 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 119.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 70.5;dendritic cells: 61.3;Endometrial ciliated cells: 62.3;Glandular and luminal cells: 101.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048606, HPA059863" Approved Supported "Nuclear speckles,Plasma membrane" NA NA 39000 "Cluster 38: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 7: Non-specific - Mitochondria" "Nuclear speckles, Plasma membrane" "HPA048606: AB_2680461, HPA059863: AB_2684146" "unprognostic (4.34e-1)" "unprognostic (5.56e-2)" "unprognostic (9.88e-2)" "unprognostic (2.15e-2)" "unprognostic (2.04e-1)" "unprognostic (4.23e-3)" "unprognostic (1.74e-1)" "unprognostic (1.01e-1)" "unprognostic (1.46e-2)" "unprognostic (6.52e-2)" "unprognostic (5.45e-3)" "unprognostic (7.98e-2)" "unprognostic (5.62e-3)" "unprognostic (7.21e-3)" "unprognostic (3.08e-1)" "unprognostic (6.86e-2)" "unprognostic (7.81e-2)" 15.7 14.5 65.2 29.5 109.6 30.0 24.7 64.2 67.6 23.2 19.0 27.8 24.5 22.6 27.0 20.1 20.0 28.4 16.9 56.2 91.6 29.5 33.3 21.5 40.6 91.3 88.0 20.0 18.8 22.6 8.3 16.4 106.0 26.4 26.3 28.1 21.8 20.2 19.8 32.8 44.1 19.7 64.4 31.4 40.3 27.5 86.6 48.7 29.9 20.7 39.0 28.5 13.0 119.1 97.8 32.2 41.5 49.6 30.0 36.0 31.5 61.5 62.6 85.3 94.3 31.5 113.8 82.2 58.8 95.3 67.2 31.7 26.5 45.1 149.4 36.3 12.0 28.3 41.3 24.7 39.5 22.0 26.3 39.4 29.2 47.2 67.5 50.0 32.1 37.1 29.4 54.6 58.1 33.5 59.0 25.1 10.1 9.7 9.5 53.7 33.0 45.8 49.9 65.6 20.0 18.7 65.0 21.7 46.4 30.9 38.4 53.8 29.8 48.3 85.9 29.8 80.8 47.2 31.7 69.8 31.6 35.9 28.1 13.1 4.1 5.5 5.2 5.8 4.8 4.7 3.9 4.6 3.5 3.7 4.5 4.8 9.2 3.9 5.1 2.2 3.8 2.8 65.2 109.6 64.2 67.6 56.2 91.6 91.3 88.0 106.0 64.4 86.6 119.1 53.0 70.5 57.5 0.0 13.2 0.0 0.0 0.0 0.0 0.0 39.4 24.8 0.0 0.0 31.6 53.3 0.0 6.5 61.3 0.0 11.7 26.7 0.0 62.3 50.0 26.1 0.0 0.0 0.0 24.9 11.2 16.2 0.0 101.9 27.8 47.8 0.0 0.0 40.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.4 0.0 0.0 5.7 0.0 0.0 0.0 0.0 50.3 0.0 0.0 13.3 0.0 0.0 41.7 24.0 0.0 0.0 0.0 17.1 0.0 0.0 0.0 0.0 8.9 20.0 51.4 0.0 0.0 ERCC8 "CKN1, CSA" ENSG00000049167 "ERCC excision repair 8, CSA ubiquitin ligase complex subunit" Q13216 5 60866454-60945073 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Cockayne syndrome, Deafness, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 47.3;Excitatory neurons: 51.8;Inhibitory neurons: 47.9;Oligodendrocyte precursor cells: 44.2;Oligodendrocytes: 57.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029328 Approved "Nuclear speckles" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" "Nuclear speckles" "HPA029328: AB_2673000" "unprognostic (5.45e-2)" "unprognostic (1.90e-1)" "unprognostic (2.56e-2)" "unprognostic (6.59e-2)" "unprognostic (1.68e-2)" "unprognostic (4.96e-2)" "unprognostic (2.10e-3)" "unprognostic (9.68e-2)" "unprognostic (3.85e-2)" "unprognostic (3.23e-1)" "unprognostic (7.49e-2)" "unprognostic (1.09e-1)" "unprognostic (4.75e-3)" "unprognostic (1.78e-2)" "unprognostic (1.97e-1)" "unprognostic (6.31e-3)" "unprognostic (7.19e-2)" 3.4 3.1 2.3 1.6 2.4 2.0 3.1 3.1 3.2 2.5 1.5 2.6 1.7 3.0 1.4 2.8 2.4 1.9 3.2 2.3 1.7 4.0 3.2 2.2 1.6 1.9 1.8 2.7 2.7 3.0 2.5 2.1 2.1 2.2 2.4 2.7 2.7 2.1 3.0 2.4 2.2 2.3 1.4 2.6 2.5 4.1 2.0 2.8 2.9 2.9 2.2 2.5 2.6 2.9 4.8 4.9 7.3 9.5 6.0 4.2 8.2 7.6 6.4 8.9 9.2 6.9 8.6 7.3 9.4 4.2 14.4 4.0 10.6 7.4 11.1 7.6 6.0 5.3 7.3 7.7 5.0 4.9 4.5 6.5 6.5 6.1 7.5 3.3 9.9 8.8 8.0 4.2 5.2 8.1 6.9 8.0 6.5 2.8 3.1 11.0 9.6 9.1 4.7 5.9 6.1 11.3 8.6 3.6 6.5 7.6 11.2 3.6 3.8 3.8 7.4 7.6 10.1 5.5 11.9 12.7 5.9 10.1 8.3 0.5 4.2 0.9 3.1 3.4 2.5 2.7 2.4 2.8 7.1 1.8 2.8 3.2 0.7 2.2 1.4 3.5 3.3 2.1 2.3 2.4 3.1 3.2 2.3 1.7 1.9 1.8 2.1 1.4 2.0 2.9 3.4 3.2 4.6 28.4 6.6 2.9 3.1 6.9 9.6 0.0 4.9 5.5 4.1 7.2 3.3 16.5 0.0 7.7 4.2 1.6 15.6 5.0 47.3 4.3 7.2 3.9 0.0 10.5 51.8 5.2 9.2 5.2 5.1 3.1 5.7 8.1 3.9 5.0 6.4 0.0 47.9 3.8 4.1 7.1 5.5 11.2 4.7 6.5 7.2 20.6 7.9 0.0 6.2 44.2 57.4 5.2 2.2 3.0 11.1 3.8 2.0 7.1 6.3 0.0 0.0 4.0 4.6 22.5 9.2 10.4 4.3 3.4 6.5 8.9 4.4 3.5 ESX1 "ESX1L, ESXR1" ENSG00000123576 "ESX homeobox 1" Q8N693 X 104250038-104254933 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 69 "testis: 8.9" "Cell type enriched" "Detected in some" 25 "Spermatogonia: 98.0" "Cancer enriched" "Detected in single" 5 "testis cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "TIME: 24.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA051992, HPA073330" Enhanced Supported "Nuclear speckles" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nuclear speckles" "HPA051992: AB_2681684, HPA073330: " "unprognostic (1.87e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 24.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 98.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 EXOSC7 "EAP1, hRrp42p, KIAA0116, p8, RRP42, Rrp42p" ENSG00000075914 "Exosome component 7" Q15024 3 44975241-45036066 "Predicted intracellular proteins" "rRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036182, HPA057980" Approved Supported "Nuclear speckles" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 24: NB-4 - Immune response" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "HPA036182: AB_10673346, HPA057980: AB_2683571" "unprognostic (1.69e-2)" "unprognostic (3.92e-3)" "unprognostic (1.84e-3)" "unprognostic (4.97e-2)" "unprognostic (3.00e-3)" "unprognostic (2.16e-1)" "unprognostic (2.34e-3)" "unprognostic (2.21e-2)" "unprognostic (2.96e-1)" "unprognostic (7.85e-2)" "unprognostic (1.20e-1)" "unprognostic (7.67e-3)" "prognostic favorable (2.69e-4)" "unprognostic (4.33e-1)" "unprognostic (7.30e-2)" "unprognostic (2.94e-1)" "unprognostic (1.20e-1)" 17.5 44.1 9.5 12.5 9.5 17.2 18.4 10.0 10.4 23.5 10.7 15.3 11.6 20.4 7.0 27.2 17.0 9.1 27.0 9.5 10.9 22.2 18.1 15.0 19.6 10.4 9.8 19.0 18.6 20.1 17.3 15.4 10.1 15.9 10.8 5.9 17.5 15.9 43.8 44.6 13.2 11.2 9.7 15.3 20.0 23.2 10.5 20.2 19.9 36.4 16.8 22.7 22.2 9.8 61.5 55.7 44.9 37.3 45.9 50.0 40.5 26.2 42.2 56.0 57.7 93.3 47.8 77.4 40.3 45.6 42.6 33.9 55.9 72.2 46.0 52.3 49.2 67.5 64.5 91.5 88.7 95.3 26.5 44.1 45.6 61.2 123.6 36.5 54.8 84.9 107.4 37.8 40.3 63.2 68.6 167.9 54.3 55.2 78.4 33.8 41.7 117.7 51.0 85.5 20.9 31.4 37.0 31.6 39.7 38.4 46.7 77.9 39.3 28.8 43.0 48.3 71.7 47.1 47.5 92.6 42.4 131.6 26.2 6.8 41.3 7.6 38.8 41.5 43.6 71.3 44.6 40.2 66.0 59.7 51.8 41.4 2.1 58.3 31.5 40.2 47.7 45.4 9.5 9.5 10.0 10.4 9.5 10.9 10.4 9.8 10.1 9.7 10.5 9.8 25.0 35.3 30.1 16.0 23.2 61.8 68.8 97.2 47.3 29.5 23.9 43.2 39.0 21.5 46.5 35.0 18.8 67.8 22.1 8.6 135.0 51.7 3.9 23.7 34.8 24.0 13.1 19.6 19.9 46.7 62.4 32.7 23.0 21.7 15.2 33.0 18.2 28.6 46.5 20.2 22.5 19.3 79.3 14.2 22.6 8.3 47.8 17.4 26.6 8.4 20.6 37.6 33.0 10.6 14.0 41.7 10.3 41.0 19.4 74.8 17.7 47.4 34.3 23.4 13.1 25.7 53.9 53.7 66.3 35.5 74.2 63.1 26.2 52.2 24.3 56.3 FAM107A "DRR1, TU3A" ENSG00000168309 "Family with sequence similarity 107 member A" O95990 3 58564117-58627610 "Predicted intracellular proteins" "Cell cycle, Growth regulation, Stress response" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "brain: 1923.8;choroid plexus: 1389.1" "Cell type enhanced" "Detected in many" "Adipocytes: 196.3;Astrocytes: 81.9;Endothelial cells: 121.3;Hepatic stellate cells: 150.6;Muller glia cells: 125.0" "Cancer enriched" "Detected in many" 6 "glioma: 110.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "ASC diff: 20.7;HUVEC TERT2: 64.9" "Low region specificity" "Detected in all" HPA055888 Enhanced Supported "Nuclear speckles" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles" "HPA055888: AB_2682957" "unprognostic (1.20e-2)" "unprognostic (1.19e-3)" "unprognostic (1.47e-2)" "prognostic unfavorable (3.56e-4)" "unprognostic (3.11e-1)" "unprognostic (7.80e-3)" "prognostic favorable (3.38e-4)" "unprognostic (1.92e-1)" "unprognostic (1.64e-1)" "unprognostic (5.73e-2)" "unprognostic (7.82e-3)" "unprognostic (2.22e-2)" "unprognostic (1.33e-2)" "unprognostic (1.33e-2)" "unprognostic (2.82e-1)" "unprognostic (1.92e-1)" "unprognostic (7.95e-3)" 73.2 7.5 1824.7 8.3 1801.2 0.3 58.6 1490.8 1923.8 34.5 1389.1 36.9 5.4 36.3 53.3 29.2 87.0 16.0 140.4 1745.7 1736.7 45.0 5.5 93.2 3.1 1611.9 1644.5 11.8 23.3 5.9 109.6 29.4 1613.0 80.5 16.0 85.1 40.6 38.0 26.3 23.3 45.2 42.5 1564.5 25.7 37.7 5.7 1698.7 43.9 51.4 32.8 8.6 68.9 41.6 1770.4 0.0 0.0 0.9 0.0 20.7 1.3 0.3 0.1 0.0 0.1 0.2 0.0 0.1 0.1 5.8 0.0 0.2 0.4 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 1.4 0.0 0.1 0.1 0.3 64.9 0.0 0.0 0.9 0.0 0.0 0.0 0.3 0.4 0.0 0.1 0.2 0.1 0.2 0.1 0.0 0.2 0.2 0.0 0.1 0.0 0.2 0.2 0.0 3.6 0.3 0.2 0.2 0.1 0.1 0.0 0.1 1.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1824.7 1801.2 1490.8 1923.8 1745.7 1736.7 1611.9 1644.5 1613.0 1564.5 1698.7 1770.4 196.3 6.4 5.5 81.9 0.5 2.2 50.8 0.3 2.2 5.2 2.3 1.3 26.5 4.3 3.2 38.6 52.1 0.1 0.4 0.0 9.8 1.1 14.5 23.2 2.4 121.3 3.6 2.7 1.4 0.2 0.0 18.4 0.0 39.3 1.3 5.9 150.6 1.6 0.0 3.3 5.3 0.0 0.0 2.2 3.7 32.4 32.9 1.9 5.4 14.0 0.0 125.0 0.0 2.0 0.6 0.3 0.0 11.7 1.3 7.3 0.2 4.5 2.3 50.2 6.6 6.6 10.4 0.7 0.4 0.4 2.7 0.0 1.0 0.5 0.0 2.2 FAM120C "CXorf17, FLJ20506, ORF34" ENSG00000184083 "Family with sequence similarity 120C" Q9NX05 X 54068324-54183281 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 33.2;Oligodendrocytes: 32.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047677 Uncertain Approved "Nuclear speckles" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 68: Oligodendrocytes - Mixed function" "Nuclear speckles" "HPA047677: AB_2680118" "unprognostic (4.70e-2)" "unprognostic (2.58e-3)" "unprognostic (3.72e-2)" "unprognostic (2.20e-2)" "unprognostic (3.21e-2)" "prognostic favorable (4.48e-4)" "unprognostic (1.86e-2)" "unprognostic (3.53e-3)" "unprognostic (2.74e-2)" "unprognostic (4.90e-2)" "unprognostic (2.71e-3)" "unprognostic (1.44e-1)" "unprognostic (1.68e-2)" "unprognostic (1.76e-3)" "unprognostic (5.21e-2)" "unprognostic (5.28e-2)" "unprognostic (3.28e-2)" 3.1 3.7 8.3 1.8 9.9 3.4 2.9 8.1 8.9 3.9 2.3 2.9 1.3 3.7 5.1 3.5 3.5 1.7 2.6 7.5 9.0 3.0 3.1 2.4 2.9 11.3 9.2 4.6 2.6 4.0 4.3 2.2 8.7 3.3 1.7 5.8 2.7 3.1 5.9 3.2 2.4 2.8 9.3 3.4 2.1 2.6 9.0 4.1 3.4 2.9 3.1 3.3 3.4 11.0 4.0 7.2 3.6 8.3 8.2 5.9 6.7 3.8 6.3 5.7 6.1 3.4 4.2 5.6 2.5 3.3 8.4 10.7 10.6 2.8 5.0 4.4 11.6 3.0 11.3 5.6 3.7 2.7 3.0 4.1 3.5 5.0 5.8 6.6 3.6 5.7 3.2 4.5 4.6 10.9 4.5 10.8 6.8 2.3 15.9 5.3 5.8 5.9 4.7 2.2 5.0 5.0 9.8 7.4 2.7 8.8 8.8 2.4 6.5 5.0 6.5 6.6 3.1 5.4 5.6 4.2 5.7 8.2 6.1 0.0 1.4 0.1 1.3 0.8 1.1 2.6 1.2 1.0 2.5 2.1 1.3 1.5 0.0 0.9 0.3 3.1 0.4 0.9 8.3 9.9 8.1 8.9 7.5 9.0 11.3 9.2 8.7 9.3 9.0 11.0 4.5 3.2 2.6 21.9 7.8 5.9 5.4 5.0 15.4 10.5 5.5 3.7 5.7 8.6 2.5 0.0 4.2 8.9 4.6 0.8 9.8 3.0 0.1 7.0 7.2 5.5 4.8 7.4 18.1 2.7 5.5 5.5 3.1 7.7 2.5 9.2 5.3 6.1 4.1 6.7 19.0 1.1 2.0 3.2 4.7 0.7 6.5 5.3 1.8 10.3 3.5 5.1 8.2 33.2 32.9 1.5 1.6 4.9 3.0 3.3 0.8 5.6 3.9 8.6 0.0 9.0 5.4 2.0 6.9 12.0 4.7 2.5 5.6 8.7 2.5 3.4 FAM160B1 "bA106M7.3, KIAA1600" ENSG00000151553 "Family with sequence similarity 160 member B1" Q5W0V3 10 114821744-114899832 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 53.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043624 Uncertain Approved "Nuclear speckles,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" Cytosol "HPA043624: AB_10797145" "unprognostic (2.61e-1)" "unprognostic (2.47e-2)" "unprognostic (2.62e-1)" "unprognostic (8.45e-3)" "unprognostic (6.43e-2)" "unprognostic (9.87e-3)" "unprognostic (7.98e-2)" "unprognostic (3.01e-1)" "unprognostic (2.29e-1)" "unprognostic (2.45e-1)" "unprognostic (1.04e-1)" "unprognostic (3.87e-2)" "prognostic unfavorable (4.02e-6)" "unprognostic (3.41e-3)" "unprognostic (3.35e-1)" "unprognostic (2.10e-1)" "unprognostic (1.25e-2)" 15.0 11.7 8.7 10.0 8.4 53.3 11.9 6.1 8.4 12.1 6.1 10.7 12.7 16.0 10.0 7.3 12.3 10.5 14.2 7.8 6.5 7.9 19.0 11.6 12.6 5.6 6.5 14.3 9.8 11.9 7.4 14.9 6.1 10.5 8.1 11.5 8.5 11.3 20.3 8.6 13.2 16.9 5.3 11.4 10.1 18.8 6.9 11.2 11.7 12.3 9.6 11.9 10.0 5.2 16.7 8.9 9.6 14.3 22.9 26.0 11.2 29.7 28.8 16.8 13.4 3.1 6.3 9.9 9.1 27.2 4.3 11.0 4.7 11.9 19.8 36.2 10.2 3.9 16.5 7.2 16.7 10.6 12.8 20.4 11.3 12.5 20.2 36.0 22.9 20.0 5.6 24.4 31.7 7.7 19.0 10.5 6.3 4.8 6.6 16.3 16.3 6.6 11.3 9.9 2.1 8.6 13.2 13.6 15.5 11.3 5.4 6.0 23.1 10.4 6.6 30.7 10.4 10.0 3.0 11.2 13.4 26.0 10.0 19.9 3.2 4.7 5.4 2.4 4.0 3.7 7.4 9.2 3.6 3.6 4.0 5.5 15.2 4.9 2.8 3.7 10.5 2.7 8.7 8.4 6.1 8.4 7.8 6.5 5.6 6.5 6.1 5.3 6.9 5.2 25.9 16.0 8.1 20.5 10.9 7.0 7.9 8.0 14.8 13.9 9.4 6.7 19.5 4.3 8.4 3.7 12.5 12.7 14.1 9.0 1.9 10.2 26.7 12.0 26.2 19.8 7.8 9.9 26.5 9.6 10.2 19.2 23.0 16.8 2.5 29.6 23.9 31.3 6.3 10.1 27.4 9.2 4.1 15.6 6.8 36.0 28.6 11.3 3.6 25.3 11.4 8.3 25.7 28.1 13.8 15.1 3.7 22.2 20.1 19.5 20.8 6.6 8.7 16.9 6.6 13.2 14.4 14.9 6.4 8.9 4.8 12.6 17.5 15.0 5.8 14.8 FAM174C "C19orf24, FLJ20640" ENSG00000228300 "Family with sequence similarity 174 member C" Q9BVV8 19 1275530-1279244 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Cytotrophoblasts: 89.9;Extravillous trophoblasts: 148.9;Hofbauer cells: 121.6;Syncytiotrophoblasts: 96.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043279, HPA047026" Uncertain Approved "Nuclear speckles,Golgi apparatus" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles" "Golgi apparatus" "HPA043279: AB_10794656, HPA047026: AB_2679906" "unprognostic (1.10e-1)" "unprognostic (3.39e-1)" "unprognostic (1.12e-1)" "unprognostic (1.65e-3)" "unprognostic (7.05e-2)" "unprognostic (4.90e-1)" "unprognostic (4.23e-3)" "unprognostic (3.12e-2)" "unprognostic (1.18e-1)" "unprognostic (3.59e-2)" "unprognostic (1.40e-2)" "unprognostic (1.15e-1)" "unprognostic (1.81e-1)" "unprognostic (2.54e-3)" "unprognostic (2.16e-1)" "unprognostic (1.10e-1)" "unprognostic (2.25e-2)" 43.0 73.4 32.9 27.6 34.5 24.8 38.9 34.2 45.8 34.0 36.2 36.6 27.6 36.6 11.5 52.3 29.5 20.0 33.4 32.6 31.5 52.3 121.9 31.7 31.8 34.9 33.4 27.7 56.1 12.1 42.3 16.5 35.5 49.2 7.2 2.1 40.8 16.4 21.8 48.5 36.4 9.5 32.7 54.1 42.9 44.7 34.6 17.7 44.7 4.8 10.4 40.1 33.4 34.9 97.3 90.3 8.6 72.6 13.8 32.7 34.0 48.0 24.8 48.2 42.4 102.8 52.2 29.5 64.3 16.5 32.0 51.5 15.3 48.8 5.6 103.2 87.0 31.2 79.1 61.1 57.6 67.1 65.3 39.2 61.1 36.3 16.0 14.0 35.2 85.3 61.1 153.8 19.6 96.0 78.9 94.4 43.7 45.4 96.4 58.2 17.4 172.4 26.9 50.5 60.4 39.6 31.0 69.2 109.0 5.9 50.5 105.1 24.2 86.6 27.9 106.6 111.2 102.4 146.1 36.6 93.5 80.2 79.2 46.6 94.6 35.3 107.8 104.2 106.6 153.2 114.9 114.2 97.9 136.8 106.2 109.0 16.4 78.5 93.5 165.3 121.5 81.4 32.9 34.5 34.2 45.8 32.6 31.5 34.9 33.4 35.5 32.7 34.6 34.9 16.4 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.0 89.9 17.6 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 148.9 7.3 0.0 0.0 0.0 0.0 0.0 0.0 121.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 96.2 3.0 0.0 0.0 0.0 FAM178B LOC51252 ENSG00000168754 "Family with sequence similarity 178 member B" Q8IXR5 2 96875882-96986580 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 18.9;brain: 10.5;epididymis: 5.5;lymphoid tissue: 12.1;testis: 8.2" "Cell type enriched" "Detected in many" 4 "Erythroid cells: 88.3" "Cancer enriched" "Detected in many" 5 "melanoma: 8.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "K-562: 25.7;OE19: 7.0;RPMI-8226: 28.0;WM-115: 27.2" "Not detected" "Not detected" "Region enhanced" "Detected in some" "spinal cord: 2.4" "HPA042516, HPA062110" Uncertain Uncertain "Nuclear speckles,Golgi apparatus" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 25: RPMI-8226 - Immune response" "Cluster 33: Fibroblasts - ECM organization" "Nuclear speckles" "Golgi apparatus" "HPA042516: AB_10806241, HPA062110: " "unprognostic (2.47e-2)" "unprognostic (1.76e-1)" "unprognostic (1.08e-2)" "unprognostic (8.04e-4)" "unprognostic (1.39e-1)" "unprognostic (1.28e-2)" "unprognostic (9.02e-4)" "unprognostic (4.70e-2)" "unprognostic (8.55e-2)" "unprognostic (6.49e-3)" "unprognostic (1.49e-1)" "unprognostic (5.13e-2)" "unprognostic (9.82e-11)" "unprognostic (6.93e-2)" "unprognostic (1.57e-1)" "unprognostic (9.63e-3)" "unprognostic (1.08e-1)" 1.7 0.0 4.9 0.0 8.7 18.9 0.9 6.3 7.3 0.5 2.3 2.2 0.0 1.6 5.5 0.7 1.3 0.1 0.4 4.7 6.8 0.1 0.0 0.4 0.1 7.7 8.0 0.5 0.0 0.0 0.1 0.9 7.4 1.1 0.1 0.1 0.3 0.8 0.2 1.2 0.5 0.4 6.5 12.1 0.3 8.2 7.3 0.1 0.1 0.0 0.0 2.1 0.8 10.5 6.2 0.0 0.0 2.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.7 0.0 0.5 2.5 0.0 0.0 0.2 7.0 0.0 0.0 6.7 28.0 0.0 0.0 0.8 0.0 0.0 4.3 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.6 0.0 0.0 0.0 27.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.1 0.0 0.1 4.9 8.7 6.3 7.3 4.7 6.8 7.7 8.0 7.4 6.5 7.3 10.5 0.2 0.0 0.0 1.0 1.2 0.8 0.6 0.4 0.0 0.2 0.5 1.4 0.4 0.0 0.0 0.0 2.1 3.2 0.5 0.1 0.0 0.0 3.6 0.1 0.3 0.2 0.0 88.3 7.2 0.0 7.1 3.0 0.0 0.1 0.0 0.2 0.4 0.0 1.2 1.7 1.1 0.0 10.2 0.0 0.9 7.8 0.9 1.0 3.6 1.0 0.2 2.9 1.0 1.0 20.7 0.2 0.1 0.0 0.1 0.3 0.0 0.0 0.4 0.2 0.0 2.8 1.6 3.2 20.1 0.6 1.7 2.5 0.2 0.3 0.1 0.4 FAM227B "C15orf33, FLJ32800" ENSG00000166262 "Family with sequence similarity 227 member B" Q96M60 15 49326962-49620929 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 39.5;Early spermatids: 41.0;Oligodendrocytes: 55.1;Spermatocytes: 48.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA049774, HPA061695" Uncertain Approved "Nuclear speckles" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 21: Non-specific - Transcription" "Cluster 29: U-266 - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" "HPA049774: AB_2680873, HPA061695: AB_2684588" "unprognostic (1.19e-2)" "unprognostic (2.57e-1)" "unprognostic (1.89e-2)" "unprognostic (4.74e-3)" "unprognostic (1.17e-1)" "unprognostic (1.80e-1)" "unprognostic (5.28e-4)" "unprognostic (3.32e-2)" "unprognostic (9.21e-2)" "unprognostic (6.57e-3)" "unprognostic (6.32e-3)" "unprognostic (6.41e-2)" "unprognostic (7.48e-5)" "unprognostic (2.70e-1)" "unprognostic (9.01e-2)" "unprognostic (7.47e-2)" "unprognostic (1.76e-1)" 1.1 5.1 4.2 1.9 5.1 1.5 6.6 4.2 5.2 4.7 4.6 4.3 2.8 6.3 7.3 3.5 7.7 3.4 7.3 3.9 4.8 7.7 7.5 2.7 4.8 4.8 5.0 9.9 6.4 5.6 6.4 1.3 5.2 5.7 2.8 7.9 5.3 5.1 7.9 3.9 2.3 3.9 4.9 2.8 3.6 10.4 4.5 6.8 7.4 8.9 4.4 3.5 2.2 6.3 0.8 0.7 5.1 2.8 1.5 3.0 0.6 2.1 2.8 3.2 5.1 0.7 2.4 1.5 4.9 3.5 3.7 0.8 1.8 3.1 3.7 3.7 1.5 3.2 1.3 1.7 4.2 1.5 1.3 3.1 4.0 1.8 2.0 6.2 3.0 7.7 5.4 2.4 7.1 3.5 3.2 1.3 2.0 1.2 1.3 2.7 4.5 8.1 4.8 1.0 3.8 5.3 1.9 2.5 6.2 3.7 3.1 1.1 2.2 2.2 1.7 3.0 1.3 12.2 9.8 4.8 2.4 3.9 2.4 5.8 0.2 1.7 3.4 0.5 4.5 2.8 3.5 4.6 0.3 3.5 5.8 5.6 0.3 2.7 0.6 3.4 3.4 2.0 4.2 5.1 4.2 5.2 3.9 4.8 4.8 5.0 5.2 4.9 4.5 6.3 1.1 9.6 4.8 39.5 5.8 2.8 5.4 5.4 3.4 4.3 6.2 7.6 10.8 1.5 9.4 3.7 0.0 1.7 3.3 1.3 25.4 3.9 41.0 19.1 3.1 2.8 8.4 2.1 12.8 3.2 1.5 3.7 3.6 3.2 3.8 1.8 1.8 4.1 0.6 5.0 12.1 1.8 6.1 0.6 2.0 21.1 4.1 2.0 3.6 5.6 0.6 11.7 4.1 16.1 55.1 2.5 1.6 3.0 6.1 2.6 1.9 12.5 21.3 8.0 0.0 4.7 2.0 48.7 13.2 2.5 4.3 0.4 5.7 6.3 2.2 2.6 FAM71A FLJ32796 ENSG00000162771 "Family with sequence similarity 71 member A" Q8IYT1 1 212624474-212626775 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 105 "testis: 78.7" "Group enriched" "Detected in many" 50 "Early spermatids: 1174.2;Late spermatids: 453.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA028462, HPA060344" Enhanced Approved "Nuclear speckles" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" "Nuclear speckles" "HPA028462: AB_10601904, HPA060344: " 0.4 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.3 0.0 0.0 0.1 78.7 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 3.8 0.0 3.7 0.0 0.1 0.5 1.7 4.4 0.6 0.1 3.5 6.7 0.0 4.3 3.3 0.0 0.0 2.6 0.3 1.9 0.0 0.7 1174.2 7.2 2.8 1.6 1.2 0.0 0.0 1.2 1.5 1.8 9.7 16.0 1.3 0.0 1.8 0.4 1.2 0.0 0.0 2.8 0.0 0.0 0.3 453.8 5.3 2.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.9 2.8 2.6 0.6 2.5 0.4 0.0 1.5 0.0 0.0 3.2 2.7 3.9 2.4 0.8 0.1 2.9 0.8 0.1 2.0 0.5 FASTK FAST ENSG00000164896 "Fas activated serine/threonine kinase" Q14296 7 151076593-151080866 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Apoptosis "Kinase, RNA-binding, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031621, CAB032539" Approved Supported "Nuclear speckles,Mitochondria" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Nuclear speckles" "CAB032539: AB_2101115, HPA031621: AB_10611966" "unprognostic (7.67e-2)" "unprognostic (6.41e-3)" "prognostic unfavorable (4.73e-4)" "unprognostic (2.60e-1)" "unprognostic (1.75e-3)" "unprognostic (2.03e-3)" "unprognostic (1.14e-3)" "unprognostic (1.01e-1)" "unprognostic (1.24e-1)" "unprognostic (4.66e-2)" "prognostic favorable (3.99e-4)" "unprognostic (3.49e-2)" "unprognostic (2.79e-2)" "unprognostic (4.12e-2)" "unprognostic (1.05e-1)" "unprognostic (1.09e-1)" "unprognostic (8.17e-2)" 23.4 36.5 35.5 13.4 33.8 8.2 21.7 32.3 50.6 23.5 30.1 31.5 26.2 23.3 11.9 39.5 21.1 14.5 66.9 34.8 32.9 34.9 58.0 18.8 14.4 34.2 33.9 24.6 28.1 31.0 41.2 9.4 34.5 34.1 11.8 7.9 27.8 18.8 122.6 28.2 25.0 11.8 33.1 24.8 29.0 21.8 35.7 14.7 26.9 95.3 10.5 26.7 25.1 34.3 39.3 45.0 13.9 34.9 50.4 22.4 22.8 29.9 40.1 25.3 29.7 31.5 34.9 9.2 41.0 40.9 46.9 24.1 13.5 36.4 6.1 26.9 23.8 11.4 12.7 27.8 62.7 9.0 25.2 29.8 51.8 29.4 21.5 20.9 30.0 22.4 17.0 20.2 29.2 80.4 20.4 23.5 24.6 47.8 50.8 13.2 17.4 30.4 34.2 27.8 16.4 18.2 40.3 62.5 43.0 11.5 34.4 31.2 24.0 32.7 7.5 31.7 28.0 50.5 33.0 6.5 66.2 19.0 39.8 18.0 31.5 30.1 22.3 32.5 23.4 19.5 23.4 23.4 28.4 21.6 25.5 21.9 6.8 20.4 32.5 38.2 28.3 21.9 35.5 33.8 32.3 50.6 34.8 32.9 34.2 33.9 34.5 33.1 35.7 34.3 21.2 0.0 7.0 17.9 34.3 24.6 37.8 68.8 23.3 42.9 31.7 26.9 18.9 30.0 43.6 25.8 25.0 49.2 38.2 59.2 86.1 49.4 10.0 22.5 21.3 22.9 44.9 28.2 12.7 47.6 26.8 33.8 54.6 24.8 38.8 38.6 23.6 37.1 43.3 37.0 13.6 54.9 59.0 26.3 22.5 20.2 36.4 25.8 94.3 7.5 35.3 54.7 44.3 9.5 10.7 38.6 40.0 34.3 46.1 27.7 86.6 66.3 24.9 51.1 13.1 33.7 35.0 58.5 70.7 36.0 25.3 60.5 34.8 50.1 61.2 35.0 FBXL4 "FBL4, FBL5" ENSG00000112234 "F-box and leucine rich repeat protein 4" Q9UKA2 6 98868535-98948006 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 97.0;Oligodendrocytes: 94.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029140, CAB033362" Approved Supported "Nuclear speckles" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 1: Thyroid gland - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 68: Oligodendrocytes - Mixed function" "Nuclear speckles" "CAB033362: AB_2103974, HPA029140: AB_10611967" "unprognostic (1.24e-1)" "unprognostic (5.10e-2)" "unprognostic (1.10e-2)" "unprognostic (1.42e-1)" "unprognostic (3.34e-2)" "unprognostic (1.66e-1)" "unprognostic (2.03e-1)" "unprognostic (3.10e-1)" "unprognostic (2.79e-1)" "unprognostic (2.68e-1)" "unprognostic (4.53e-2)" "unprognostic (1.14e-1)" "unprognostic (1.05e-2)" "unprognostic (1.09e-1)" "unprognostic (1.70e-1)" "unprognostic (1.65e-1)" "unprognostic (2.62e-1)" 5.8 8.0 5.9 5.3 8.4 5.1 7.7 7.6 5.5 7.0 5.5 6.2 5.9 6.9 11.2 5.3 7.7 6.6 5.9 4.6 7.1 13.1 15.7 5.9 6.1 8.0 8.3 8.2 9.4 12.7 4.8 6.8 8.4 8.0 6.9 5.1 9.9 6.6 9.4 5.7 5.8 6.2 7.2 5.3 7.4 4.1 7.4 9.0 12.2 7.2 6.4 5.7 5.3 11.0 5.7 9.0 7.6 10.2 12.5 22.8 8.2 12.7 10.7 7.3 10.3 4.1 10.7 13.1 11.5 10.6 12.8 8.1 8.8 9.2 11.1 21.4 7.2 9.3 6.2 9.4 9.7 11.5 8.9 13.0 16.4 6.6 18.4 20.4 9.5 10.2 12.6 10.1 13.4 5.6 4.3 5.5 4.0 7.5 5.5 14.6 5.2 10.7 13.9 8.2 9.5 7.7 6.7 8.9 12.2 9.2 6.6 8.2 13.3 8.4 3.7 11.9 9.3 3.4 3.4 5.5 10.5 10.4 10.2 18.4 4.7 13.0 4.6 4.5 6.1 7.1 4.6 4.6 3.8 5.7 5.9 5.6 5.9 4.3 6.0 2.5 6.1 3.9 5.9 8.4 7.6 5.5 4.6 7.1 8.0 8.3 8.4 7.2 7.4 11.0 12.2 19.2 11.9 42.7 14.2 9.7 8.2 9.0 12.0 14.9 9.1 8.3 16.2 5.7 8.8 36.8 22.9 10.1 9.5 9.8 19.6 9.7 5.4 10.6 14.5 10.8 7.2 20.2 46.9 11.0 10.7 13.7 14.3 7.9 8.9 20.8 11.4 19.4 8.9 10.1 58.3 13.7 8.2 12.3 6.4 2.1 19.0 11.8 5.4 41.2 14.9 10.6 12.3 97.0 94.4 7.5 9.8 12.8 8.8 13.9 12.5 11.8 11.3 13.3 13.1 12.7 10.0 4.1 6.4 12.4 8.5 9.9 9.3 16.9 10.4 8.2 FBXO34 "Fbx34, FLJ20725" ENSG00000178974 "F-box protein 34" Q9NWN3 14 55271344-55370053 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 165.2;Late spermatids: 219.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052592 Uncertain Approved "Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles" "HPA052592: AB_2681877" "unprognostic (6.19e-2)" "unprognostic (1.73e-1)" "unprognostic (5.47e-2)" "unprognostic (6.35e-2)" "unprognostic (1.60e-1)" "unprognostic (1.44e-2)" "unprognostic (1.18e-1)" "unprognostic (9.87e-3)" "unprognostic (3.07e-2)" "unprognostic (1.67e-1)" "unprognostic (1.04e-2)" "unprognostic (1.30e-1)" "prognostic favorable (1.20e-13)" "unprognostic (4.49e-2)" "unprognostic (3.14e-1)" "unprognostic (2.04e-1)" "unprognostic (1.23e-1)" 9.0 7.9 7.8 11.9 10.7 17.2 12.6 6.5 14.9 12.3 7.1 27.3 14.4 11.0 15.9 33.5 15.0 13.3 13.1 14.4 6.2 18.3 12.0 15.2 12.8 4.6 5.8 11.6 10.5 11.6 6.5 10.0 4.7 12.9 26.8 16.0 17.5 11.6 31.2 12.2 15.1 11.7 4.9 13.9 18.1 24.8 6.7 17.0 22.7 44.7 15.8 16.4 16.1 7.5 30.1 17.2 13.5 12.3 17.3 14.1 14.8 14.9 25.4 22.1 25.5 15.7 37.8 24.0 12.1 12.9 14.4 29.0 17.5 15.0 28.3 14.8 10.2 25.2 10.4 9.7 13.4 30.5 23.8 11.5 21.6 15.4 15.4 17.2 17.0 25.8 19.9 18.8 14.3 20.2 24.0 21.6 8.0 26.3 13.3 25.5 33.1 13.4 20.3 34.2 14.9 16.2 18.0 17.9 14.8 16.3 21.5 19.5 13.0 19.3 24.9 10.5 11.8 9.1 8.2 27.1 13.7 16.4 11.3 9.4 11.2 2.5 9.9 7.5 11.8 7.0 10.1 10.8 11.1 7.0 8.8 9.3 6.1 13.2 14.0 5.1 6.9 8.7 7.8 10.7 6.5 14.9 14.4 6.2 4.6 5.8 4.7 4.9 6.7 7.5 16.2 22.4 31.6 22.9 27.3 21.0 32.9 18.5 15.9 36.7 15.6 12.7 21.5 7.2 32.5 18.4 22.9 13.9 57.8 63.7 17.6 22.8 165.2 27.1 17.4 24.1 26.4 52.8 109.1 30.3 4.7 14.7 31.1 28.9 17.2 21.1 9.3 7.8 9.9 37.0 75.5 30.0 30.5 13.5 24.3 219.1 23.0 27.8 12.4 46.9 12.6 14.1 24.7 35.2 20.7 18.0 35.3 16.6 27.4 31.2 20.0 17.0 34.5 32.4 6.6 24.2 19.3 34.1 16.3 20.7 24.3 27.0 44.1 11.4 29.3 63.2 FCHSD2 "KIAA0769, SH3MD3" ENSG00000137478 "FCH and double SH3 domains 2" O94868 11 72836745-73142318 "Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 219.6;Microglial cells: 387.8;Oligodendrocyte precursor cells: 471.0;Oligodendrocytes: 198.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 164.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038545, HPA038546" Uncertain Approved "Nuclear speckles,Plasma membrane,Actin filaments,Focal adhesion sites" Yes No "Cluster 10: Basophils - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane, Actin filaments" "Nuclear speckles, Focal adhesion sites" "HPA038545: AB_2676074, HPA038546: AB_10673013" "unprognostic (1.80e-2)" "unprognostic (1.50e-2)" "prognostic favorable (1.71e-4)" "unprognostic (1.63e-1)" "unprognostic (3.14e-2)" "unprognostic (2.62e-3)" "unprognostic (1.41e-2)" "unprognostic (2.62e-1)" "unprognostic (1.27e-2)" "unprognostic (2.56e-1)" "unprognostic (3.69e-2)" "unprognostic (6.16e-2)" "unprognostic (2.89e-3)" "unprognostic (2.02e-1)" "unprognostic (4.70e-1)" "unprognostic (2.92e-1)" "unprognostic (1.23e-1)" 22.2 19.2 43.3 33.4 47.9 28.6 16.8 31.5 38.7 14.9 34.6 14.5 8.9 16.0 6.9 11.7 13.8 22.6 25.5 37.0 44.5 13.0 17.6 23.9 45.2 36.6 36.4 32.3 10.4 9.9 8.1 31.2 35.4 11.6 14.4 19.6 9.3 13.8 8.8 9.0 17.7 17.2 32.5 42.3 13.1 22.6 41.3 28.5 14.9 14.7 46.1 21.6 11.7 45.0 14.2 12.3 26.0 31.3 9.8 23.9 21.8 26.7 50.6 14.8 12.0 9.6 21.0 76.3 31.3 31.0 15.6 20.0 15.3 14.1 21.0 27.2 7.0 64.2 14.3 33.4 25.7 30.6 7.6 14.6 15.6 15.1 17.7 33.4 35.7 26.7 13.7 49.6 19.5 16.1 36.4 54.7 5.5 15.6 13.8 56.4 39.8 164.1 24.8 21.4 13.1 16.9 9.6 16.2 31.9 12.2 12.4 23.7 47.9 45.9 18.5 32.9 7.5 46.8 29.4 71.2 8.4 51.4 13.8 18.3 8.4 18.7 2.8 5.1 1.9 22.2 2.8 3.2 8.1 26.9 3.2 4.1 19.9 2.0 3.0 32.3 3.2 3.6 43.3 47.9 31.5 38.7 37.0 44.5 36.6 36.4 35.4 32.5 41.3 45.0 47.3 9.6 14.0 114.9 76.7 8.5 5.2 3.6 9.1 13.5 5.9 4.7 16.0 8.6 6.1 3.7 25.0 12.4 39.4 1.9 1.9 4.1 6.2 6.6 8.3 30.2 4.8 19.4 79.4 6.2 9.2 9.4 7.7 5.4 2.5 33.6 46.1 11.3 19.9 10.1 219.6 7.7 4.1 30.8 29.9 10.0 10.8 32.8 5.4 387.8 20.6 10.6 5.2 471.0 198.1 5.3 5.7 16.6 70.1 3.8 1.8 3.5 3.9 17.0 6.6 13.0 26.1 9.6 13.0 7.1 5.8 12.0 14.9 6.0 3.7 4.8 FEV Pet-1 ENSG00000163497 "FEV transcription factor, ETS family member" Q99581 2 218981087-218985184 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "brain: 70.8" "Cell type enriched" "Detected in some" 32 "Enteroendocrine cells: 744.9" "Group enriched" "Detected in some" 10 "pancreatic cancer: 3.0;prostate cancer: 9.9;stomach cancer: 2.4" "Group enriched" "Detected in many" 7 "midbrain: 70.8;pons: 20.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HMC-1: 35.5;SH-SY5Y: 43.8" "Region enhanced" "Detected in single" "midbrain: 1.9" "Group enriched" "Detected in some" 5 "midbrain: 4.8;pons: 2.7" HPA067679 Supported Supported "Nuclear speckles" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Nuclear speckles" "HPA067679: AB_2685884" "unprognostic (4.58e-1)" "unprognostic (1.60e-1)" "unprognostic (7.21e-2)" "prognostic favorable (4.85e-4)" "unprognostic (2.87e-1)" "unprognostic (3.96e-1)" "unprognostic (1.52e-1)" "unprognostic (2.15e-1)" 0.1 2.3 0.0 0.0 1.7 0.0 0.0 0.0 0.6 0.0 0.0 1.2 4.3 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.1 0.1 0.0 0.0 0.0 6.2 70.8 0.0 1.3 0.0 2.6 0.0 20.1 2.2 1.8 0.4 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.0 3.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 35.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.1 43.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.6 0.6 0.1 6.2 70.8 20.1 0.1 0.3 0.2 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 1.2 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.1 744.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 22.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.2 6.0 0.0 0.0 3.4 1.2 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.4 0.1 FIBP FGFIBP ENSG00000172500 "FGF1 intracellular binding protein" O43427 11 65883740-65888531 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 608.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011729 Approved Supported "Nuclear speckles" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear speckles" "HPA011729: AB_1848579" "unprognostic (1.70e-1)" "unprognostic (6.06e-2)" "unprognostic (1.06e-1)" "unprognostic (3.35e-1)" "unprognostic (1.37e-1)" "unprognostic (4.49e-2)" "prognostic unfavorable (1.74e-4)" "unprognostic (2.23e-1)" "unprognostic (2.95e-1)" "unprognostic (3.10e-3)" "unprognostic (2.13e-1)" "unprognostic (1.29e-1)" "unprognostic (5.50e-2)" "unprognostic (2.39e-1)" "unprognostic (3.18e-1)" "unprognostic (1.83e-2)" "unprognostic (4.89e-2)" 34.1 48.4 48.0 26.8 49.0 32.2 33.0 48.0 55.1 31.1 41.8 30.8 30.4 35.9 29.4 35.6 37.2 22.3 56.8 51.0 50.5 48.3 37.1 31.6 35.6 53.3 47.6 28.6 39.0 32.8 31.2 25.1 54.3 30.6 27.3 19.8 27.9 24.6 53.6 45.7 35.3 30.9 46.6 43.3 37.7 64.9 49.9 40.3 35.9 56.1 42.9 29.7 28.3 47.8 61.0 86.9 48.3 118.6 72.8 91.2 35.9 54.8 110.9 74.3 62.0 36.1 83.1 79.7 98.2 124.1 35.9 65.2 48.5 121.0 48.1 93.7 62.2 77.3 84.1 54.7 99.8 100.7 64.4 73.8 68.3 54.1 114.4 60.0 93.7 61.5 27.4 139.4 98.9 198.2 78.9 88.0 47.8 61.5 130.7 104.9 45.6 196.3 88.5 79.6 87.8 80.4 60.3 110.6 110.5 32.5 113.0 58.1 86.3 79.7 66.4 130.9 40.3 73.8 87.6 48.4 101.1 73.6 30.7 123.5 121.2 98.9 71.1 136.9 74.4 100.7 67.2 64.9 164.7 83.1 52.7 57.0 20.4 101.1 150.0 84.1 100.6 109.4 48.0 49.0 48.0 55.1 51.0 50.5 53.3 47.6 54.3 46.6 49.9 47.8 55.8 12.8 28.0 4.9 57.0 47.3 51.7 105.7 38.7 47.7 66.9 85.6 44.7 42.9 55.7 44.1 31.3 79.4 41.1 61.6 93.9 114.2 176.7 45.3 59.8 52.6 93.5 39.1 7.1 149.3 125.7 50.3 37.2 39.6 67.2 68.6 45.3 36.5 115.0 42.1 7.3 49.2 57.0 75.3 75.9 608.0 36.1 67.9 51.6 3.7 129.3 47.1 101.0 3.5 5.6 98.9 68.8 39.5 60.1 56.1 185.8 150.1 54.9 52.8 19.7 39.2 77.2 100.5 84.0 51.5 52.1 71.8 54.6 79.6 58.8 61.5 FLT4 "PCL, VEGFR-3, VEGFR3" ENSG00000037280 "Fms related receptor tyrosine kinase 4" P35916 5 180601506-180649624 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Adipocytes: 27.4;Endothelial cells: 27.1;Extravillous trophoblasts: 37.1;Hepatic stellate cells: 64.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "MAIT T-cell: 3.8" "Lineage enriched" "Detected in single" 31 "T-cells: 3.8" "Cell line enhanced" "Detected in some" "AN3-CA: 10.1;BEWO: 12.4;HEK 293: 15.6;HL-60: 9.5;HUVEC TERT2: 9.9;JURKAT: 12.3;T-47d: 14.6;TIME: 15.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000099, HPA046519, HPA067906, HPA074389" Approved Supported "Nuclear speckles,Plasma membrane,Cell Junctions" "Secreted to blood" NA NA 20000000 290000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 6: T47d - Mammary gland" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles, Plasma membrane" "Cell Junctions" "CAB000099: , HPA046519: AB_2732527, HPA067906: AB_2732775, HPA074389: " "unprognostic (7.35e-2)" "unprognostic (1.63e-1)" "unprognostic (9.45e-3)" "unprognostic (3.81e-1)" "unprognostic (9.26e-2)" "unprognostic (3.20e-3)" "unprognostic (1.13e-2)" "unprognostic (1.80e-2)" "unprognostic (2.19e-1)" "unprognostic (1.70e-1)" "unprognostic (2.13e-2)" "unprognostic (3.69e-1)" "unprognostic (1.88e-2)" "unprognostic (9.41e-3)" "unprognostic (1.83e-1)" "unprognostic (8.26e-2)" "unprognostic (1.32e-1)" 17.2 11.3 3.5 4.7 4.6 0.8 14.7 2.6 3.4 9.0 2.6 4.9 2.8 8.0 3.0 4.4 9.8 3.8 9.7 5.1 2.6 20.1 6.2 16.9 5.5 3.4 3.0 4.5 2.0 2.3 7.8 6.4 3.6 5.6 1.3 0.3 2.0 2.5 4.7 4.0 7.2 4.1 2.8 17.6 3.5 3.1 4.2 1.0 25.7 4.1 1.4 5.6 5.5 2.7 0.1 2.5 3.2 10.1 0.0 0.0 12.4 0.3 0.1 0.0 0.0 0.4 0.3 0.3 0.9 0.1 0.6 0.4 3.4 0.2 0.3 0.1 15.6 1.2 0.5 0.5 0.1 9.5 0.3 0.2 0.1 0.2 0.4 0.3 9.9 12.3 0.4 0.4 2.1 5.6 0.1 0.5 7.0 0.3 0.6 8.2 0.1 0.1 0.1 0.3 0.3 1.1 0.1 0.2 0.1 3.1 14.6 0.3 15.7 0.2 6.9 0.2 0.1 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.5 0.0 3.8 0.0 0.2 0.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 3.5 4.6 2.6 3.4 5.1 2.6 3.4 3.0 3.6 2.8 4.2 2.7 27.4 0.0 1.7 0.7 0.7 0.9 0.2 0.0 1.2 0.2 1.4 1.4 4.5 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.1 0.1 27.1 0.0 0.0 0.2 0.0 37.1 0.8 0.0 0.1 2.5 2.4 64.6 0.6 1.2 0.0 0.1 0.0 0.0 3.3 0.8 0.7 0.3 0.6 0.0 3.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.2 0.0 0.7 0.7 0.1 5.2 0.1 1.1 1.0 1.8 0.2 0.0 0.1 FNBP4 KIAA1014 ENSG00000109920 "Formin binding protein 4" Q8N3X1 11 47716494-47767443 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039485, HPA040029" Supported Enhanced "Nuclear speckles" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "HPA039485: AB_2676536, HPA040029: AB_2676808" "unprognostic (2.49e-2)" "unprognostic (3.95e-1)" "unprognostic (5.50e-2)" "unprognostic (2.78e-1)" "unprognostic (1.19e-1)" "unprognostic (6.13e-3)" "prognostic unfavorable (7.33e-5)" "unprognostic (5.58e-3)" "prognostic unfavorable (2.50e-4)" "unprognostic (1.60e-2)" "unprognostic (3.28e-1)" "prognostic unfavorable (6.35e-4)" "prognostic unfavorable (1.91e-8)" "unprognostic (3.54e-1)" "unprognostic (1.60e-1)" "unprognostic (3.58e-1)" "prognostic favorable (7.23e-5)" 38.0 34.4 5.8 12.1 6.1 19.6 36.6 9.9 7.4 46.7 8.4 35.4 8.9 38.9 9.4 33.8 40.6 8.2 29.9 5.7 6.8 29.5 31.3 39.1 15.9 5.9 6.2 48.8 39.2 7.5 29.2 9.6 5.8 36.3 8.8 14.9 32.7 8.2 51.0 40.5 42.8 9.0 5.3 50.6 31.6 16.5 6.4 14.0 42.8 7.0 14.2 34.2 40.2 7.8 10.6 8.5 17.7 12.5 10.0 11.6 12.0 12.3 12.7 11.1 12.9 8.4 14.0 23.2 6.0 14.0 9.3 21.2 15.8 10.0 16.4 18.2 24.1 17.5 28.1 14.3 14.1 19.5 16.6 14.2 16.4 9.7 22.0 16.2 13.1 14.1 19.2 19.2 10.7 9.7 30.0 22.6 16.7 9.4 7.8 21.2 16.8 12.9 10.9 12.8 7.9 13.1 18.5 15.2 10.5 13.2 12.3 9.1 14.4 13.1 13.8 19.0 17.3 18.6 13.4 26.1 9.5 11.9 9.1 3.8 2.1 3.4 3.7 1.5 2.9 5.1 2.6 2.6 1.3 5.4 2.7 2.9 2.0 1.8 2.2 5.6 3.9 0.9 5.8 6.1 9.9 7.4 5.7 6.8 5.9 6.2 5.8 5.3 6.4 7.8 65.0 51.3 71.7 82.6 114.7 70.9 112.5 45.9 112.7 95.1 57.0 49.0 38.2 27.1 63.6 25.8 108.4 48.9 122.0 46.1 5.9 39.9 5.5 94.3 121.9 59.7 36.5 59.1 86.7 37.8 37.4 70.6 89.2 165.4 57.6 95.5 48.2 27.0 28.4 67.3 93.6 46.5 34.6 37.2 58.3 8.0 89.5 59.2 39.2 71.2 62.1 28.1 83.4 100.5 108.3 50.8 39.4 62.1 102.4 120.8 36.6 11.3 60.5 103.2 46.0 70.5 61.6 37.3 28.1 96.0 69.9 82.9 105.7 93.4 42.6 168.0 FNDC1 "bA243O10.1, dJ322A24.1, FNDC2, KIAA1866" ENSG00000164694 "Fibronectin type III domain containing 1" Q4ZHG4 6 159169400-159272108 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 14.2;thyroid gland: 20.3" "Group enriched" "Detected in some" 4 "Fibroblasts: 28.7;Smooth muscle cells: 11.5" "Cancer enhanced" "Detected in many" "thyroid cancer: 32.5" "Group enriched" "Detected in many" 6 "cerebral cortex: 5.4;hippocampal formation: 8.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 1.0;fHDF/TERT166: 2.9;SuSa: 3.1" "Region enhanced" "Detected in many" "olfactory bulb: 7.0" "Region enhanced" "Detected in many" "spinal cord: 10.3" "HPA030962, HPA030963" Approved Approved "Nuclear speckles" "Secreted to extracellular matrix" NA NA 14000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Nuclear speckles" "HPA030962: AB_10696212, HPA030963: AB_2673676" "unprognostic (4.59e-2)" "unprognostic (9.17e-3)" "unprognostic (7.62e-2)" "prognostic favorable (6.10e-5)" "unprognostic (4.57e-1)" "unprognostic (2.11e-1)" "unprognostic (5.52e-2)" "unprognostic (1.18e-1)" "unprognostic (1.30e-1)" "unprognostic (1.08e-1)" "unprognostic (4.18e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (1.93e-6)" "unprognostic (6.49e-3)" "unprognostic (1.12e-1)" "unprognostic (3.10e-1)" "unprognostic (1.76e-3)" 5.4 0.5 0.5 1.9 0.3 0.0 2.1 0.1 5.4 6.5 0.2 12.9 2.5 2.2 0.0 1.1 0.6 14.2 3.9 8.7 0.3 0.6 0.7 1.6 2.8 0.1 1.0 1.2 1.1 0.3 0.2 0.9 0.0 0.4 1.8 0.1 0.9 0.8 2.1 0.9 4.2 11.7 0.3 0.5 0.4 0.4 0.4 0.1 20.3 9.6 2.4 1.0 1.6 1.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.0 2.9 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 3.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.1 5.4 8.7 0.3 0.1 1.0 0.0 0.3 0.4 1.2 2.6 0.0 0.6 0.0 0.0 3.2 0.0 0.0 0.0 0.3 0.1 0.5 2.1 0.0 0.6 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.3 0.4 4.7 0.7 0.0 0.0 0.2 0.0 0.2 28.7 0.0 0.3 0.0 0.1 1.4 0.0 0.2 0.0 1.7 0.0 0.0 0.0 3.1 0.0 0.3 0.2 1.8 2.8 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 3.0 11.5 1.1 1.4 0.0 1.4 0.1 0.5 0.1 0.0 0.0 FOXJ3 KIAA1041 ENSG00000198815 "Forkhead box J3" Q9UPW0 1 42176539-42335877 "Predicted intracellular proteins, Transcription factors" "Differentiation, Meiosis, Spermatogenesis, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 126.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067284 Approved "Nucleoplasm,Nuclear speckles,Vesicles" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Nuclear speckles" Vesicles "HPA067284: AB_2685817" "unprognostic (5.60e-2)" "unprognostic (2.26e-2)" "unprognostic (4.24e-2)" "unprognostic (5.15e-2)" "unprognostic (3.18e-2)" "unprognostic (1.56e-2)" "prognostic unfavorable (5.17e-6)" "unprognostic (3.65e-3)" "unprognostic (1.17e-1)" "unprognostic (1.30e-1)" "unprognostic (1.72e-1)" "unprognostic (5.14e-2)" "prognostic unfavorable (4.51e-7)" "unprognostic (2.10e-1)" "unprognostic (1.83e-1)" "unprognostic (1.87e-2)" "unprognostic (5.43e-2)" 23.2 12.9 15.6 14.9 18.6 30.2 22.2 28.6 20.1 22.6 15.2 17.8 15.7 20.2 14.8 15.5 17.9 13.1 20.1 19.7 19.6 13.4 16.2 18.5 17.8 13.4 13.2 23.1 18.9 21.4 17.1 18.4 11.9 17.1 18.1 19.4 16.9 14.6 42.1 22.9 17.6 17.7 12.5 17.2 17.5 16.4 16.2 22.2 19.2 29.2 17.3 18.3 19.1 20.6 24.8 20.5 22.1 23.0 23.3 28.5 31.7 18.4 27.1 24.2 26.8 19.0 28.9 37.8 19.1 25.8 20.7 23.1 31.1 30.2 40.8 28.5 17.5 41.7 26.3 16.3 20.1 38.7 27.4 21.3 29.3 36.2 44.6 25.7 26.7 29.6 25.7 26.6 29.2 14.1 39.3 22.0 34.4 19.8 18.3 36.4 57.9 25.9 20.5 35.4 30.6 28.8 33.1 37.8 33.1 31.4 19.0 56.9 25.0 25.1 33.5 25.7 30.8 26.2 34.8 30.2 22.7 31.6 20.7 5.1 4.9 5.5 7.2 4.3 8.9 6.4 8.9 7.9 4.0 9.2 9.3 10.7 9.3 9.9 8.9 8.3 6.2 4.2 15.6 18.6 28.6 20.1 19.7 19.6 13.4 13.2 11.9 12.5 16.2 20.6 47.5 12.8 21.3 75.4 29.5 35.4 10.9 16.7 40.5 21.4 22.9 18.3 39.9 10.0 18.5 16.5 18.8 13.9 28.8 33.2 17.6 10.7 23.7 30.6 32.0 26.7 27.0 27.3 110.8 14.7 30.8 22.6 31.6 38.1 12.7 19.3 16.4 17.0 11.7 21.9 112.6 26.5 8.2 18.6 15.3 18.4 22.4 18.7 10.6 87.1 16.0 15.0 27.8 102.5 126.6 15.9 18.9 19.9 29.2 21.4 22.6 14.8 15.1 31.3 6.6 38.3 22.0 32.1 22.5 28.2 33.4 27.9 27.7 12.6 18.9 20.8 FOXO4 "AFX1, MLLT7" ENSG00000184481 "Forkhead box O4" P98177 X 71095851-71103532 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors" "Cell cycle, Differentiation, Myogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 116.5" "Group enriched" "Detected in many" 5 "Cytotrophoblasts: 260.7;Syncytiotrophoblasts: 307.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in many" 6 "BEWO: 159.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039560, HPA040232" Enhanced Supported "Nuclear speckles,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nuclear speckles" Cytosol "HPA039560: AB_2676572, HPA040232: AB_2676894" "unprognostic (4.64e-2)" "unprognostic (2.94e-2)" "unprognostic (2.19e-1)" "unprognostic (2.49e-1)" "unprognostic (4.79e-2)" "prognostic favorable (4.61e-4)" "unprognostic (1.09e-1)" "unprognostic (3.20e-2)" "unprognostic (1.58e-1)" "unprognostic (7.18e-2)" "unprognostic (2.13e-2)" "unprognostic (8.16e-2)" "prognostic favorable (3.46e-4)" "unprognostic (2.45e-2)" "unprognostic (2.07e-1)" "unprognostic (1.20e-1)" "unprognostic (1.75e-3)" 15.8 33.6 73.9 6.5 80.6 22.0 13.9 58.9 68.7 12.9 43.1 22.1 11.0 17.1 16.4 12.0 17.6 9.4 18.2 58.3 61.8 9.4 7.2 10.0 7.1 71.7 70.5 23.2 12.7 16.0 7.0 116.5 65.3 14.3 8.0 7.5 16.7 19.2 67.3 15.1 14.3 8.2 62.3 13.9 13.5 17.3 68.8 14.5 10.9 49.4 6.4 17.2 13.2 81.6 4.6 1.2 3.4 4.9 7.9 5.7 159.1 3.4 3.9 1.8 4.5 3.3 6.5 5.9 4.7 4.5 1.9 2.1 8.8 4.2 2.2 6.0 13.7 8.5 27.3 5.0 4.8 4.9 6.9 5.1 9.7 1.7 1.1 7.9 4.7 8.4 17.5 12.5 0.8 0.9 8.6 8.0 16.9 11.5 5.6 5.7 8.5 10.1 3.0 2.6 2.8 7.3 7.1 1.1 8.3 24.7 1.9 3.1 4.3 1.1 2.3 8.3 0.8 7.7 4.3 1.0 4.3 13.6 1.3 0.0 0.1 1.0 0.2 0.1 0.0 0.2 0.1 0.2 0.0 0.2 0.1 0.4 0.9 0.2 0.1 0.0 0.3 0.3 73.9 80.6 58.9 68.7 58.3 61.8 71.7 70.5 65.3 62.3 68.8 81.6 10.1 0.0 2.7 0.3 3.8 5.4 3.9 0.6 9.1 1.3 8.2 7.7 6.6 5.7 1.5 9.2 4.2 260.7 6.5 20.6 1.9 2.7 0.3 3.2 2.8 6.1 6.1 17.7 0.8 3.0 24.3 4.0 5.1 3.1 2.5 3.1 5.0 2.9 22.3 1.7 0.8 12.2 0.0 7.1 5.2 1.4 6.8 4.4 3.6 1.0 2.6 4.4 4.1 1.0 2.2 3.1 8.6 15.4 7.3 2.5 17.1 4.4 1.5 0.8 6.6 4.0 3.8 0.6 0.4 6.0 3.4 307.8 7.0 48.3 7.4 3.8 FYTTD1 "DKFZp761B1514, UIF" ENSG00000122068 "Forty-two-three domain containing 1" Q96QD9 3 197737179-197787596 "Predicted intracellular proteins" "mRNA transport, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054474, HPA074880" Enhanced Supported "Nuclear speckles" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nuclear speckles" "HPA054474: , HPA074880: " "unprognostic (3.61e-2)" "unprognostic (6.01e-2)" "unprognostic (4.88e-2)" "prognostic unfavorable (3.08e-4)" "unprognostic (2.33e-2)" "unprognostic (3.80e-1)" "unprognostic (3.69e-2)" "unprognostic (9.57e-3)" "unprognostic (4.44e-2)" "unprognostic (1.66e-1)" "unprognostic (5.04e-3)" "unprognostic (8.74e-2)" "unprognostic (8.49e-3)" "unprognostic (3.40e-2)" "unprognostic (3.36e-1)" "unprognostic (3.29e-1)" "unprognostic (3.15e-1)" 29.7 20.9 12.1 27.1 12.6 39.2 26.6 16.1 14.6 24.8 9.1 19.9 16.7 30.4 19.6 43.9 19.1 24.4 41.3 12.1 14.9 25.7 28.9 23.6 32.4 12.4 13.9 27.5 36.4 28.7 12.6 33.5 13.0 25.1 21.6 33.8 18.2 28.8 92.6 27.1 19.3 34.9 12.8 26.3 18.2 41.1 13.3 34.1 29.6 67.0 37.7 33.6 16.9 14.9 104.5 22.6 43.7 41.7 50.1 55.3 13.4 50.0 50.8 75.4 61.4 35.3 34.8 66.4 177.1 59.3 40.0 36.7 55.5 51.0 79.8 14.5 24.9 99.8 32.9 16.1 48.9 75.1 46.5 40.0 64.6 40.8 58.3 52.1 60.4 36.8 45.9 139.0 67.6 86.9 82.2 18.1 9.6 45.1 41.2 74.9 53.6 47.4 54.8 67.3 82.4 35.7 76.8 60.0 56.4 31.8 141.2 39.1 54.0 38.5 38.1 49.0 53.6 83.5 137.2 79.3 40.8 106.4 40.6 59.2 26.9 26.5 32.4 31.8 40.7 20.0 30.7 35.9 29.9 18.9 33.4 32.2 8.5 64.6 31.0 16.9 30.2 45.7 12.1 12.6 16.1 14.6 12.1 14.9 12.4 13.9 13.0 12.8 13.3 14.9 60.6 35.3 27.2 14.7 78.5 82.3 46.6 24.3 42.7 35.1 47.0 34.4 109.7 25.8 30.1 47.8 31.3 24.4 63.9 19.0 90.1 35.5 21.7 27.3 58.9 55.2 56.4 25.2 23.7 36.1 27.5 53.7 30.1 42.6 66.6 29.4 36.4 50.7 38.0 45.4 19.6 23.7 28.5 48.6 67.8 18.3 32.0 54.8 51.6 22.5 108.6 41.8 82.4 19.6 23.0 34.3 16.5 37.2 65.4 74.5 17.1 51.1 44.6 45.2 39.5 45.8 63.1 96.3 90.7 54.0 91.1 50.1 60.7 51.9 20.0 63.6 GAB3 ENSG00000160219 "GRB2 associated binding protein 3" Q8WWW8 X 154675249-154751583 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 13.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 20.4;dendritic cells: 32.0;Erythroid cells: 20.4;granulocytes: 20.8;Kupffer cells: 24.7;Microglial cells: 30.9;NK-cells: 39.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 21.3;HMC-1: 23.3" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA010090 Approved Approved "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear speckles" "Nucleoplasm, Cytosol" "HPA010090: AB_1849362" "unprognostic (2.67e-2)" "unprognostic (1.04e-2)" "unprognostic (4.10e-2)" "unprognostic (1.15e-1)" "unprognostic (2.57e-1)" "unprognostic (3.63e-3)" "unprognostic (1.20e-1)" "unprognostic (5.90e-3)" "unprognostic (1.87e-1)" "unprognostic (1.43e-1)" "unprognostic (2.04e-2)" "unprognostic (2.92e-1)" "prognostic unfavorable (5.07e-4)" "unprognostic (1.22e-1)" "unprognostic (2.84e-2)" "unprognostic (5.87e-2)" "unprognostic (2.19e-1)" 3.7 2.1 1.8 7.0 3.5 12.5 2.3 2.6 3.4 1.8 2.2 2.6 3.4 2.0 3.8 1.7 1.9 3.7 7.4 2.0 2.6 1.0 1.9 6.0 7.6 4.7 2.2 1.3 1.0 2.7 0.4 3.7 5.0 1.3 3.4 1.2 2.1 1.9 1.3 3.6 4.2 3.5 2.1 13.9 2.6 4.9 3.6 5.2 3.6 1.6 6.6 3.1 1.1 8.6 0.8 0.0 0.7 1.0 0.9 2.3 0.5 0.3 0.6 0.2 0.3 0.0 0.5 2.5 0.7 0.0 1.5 0.4 0.6 0.4 0.0 2.9 1.0 21.3 2.9 2.4 1.6 6.5 23.3 0.9 0.2 2.0 0.8 0.8 5.2 2.0 4.8 7.3 1.0 0.3 2.4 6.6 0.2 0.0 0.1 3.5 0.0 0.3 1.3 0.0 3.0 0.4 0.3 0.3 0.4 0.5 0.9 3.7 4.8 1.2 1.9 0.8 0.6 8.0 7.0 2.5 2.0 8.4 0.6 26.4 5.9 8.7 13.3 5.7 10.2 1.0 3.5 9.7 5.8 1.3 1.2 6.8 9.0 2.5 3.6 3.3 0.8 5.0 1.8 3.5 2.6 3.4 2.0 2.6 4.7 2.2 5.0 2.1 3.6 8.6 9.9 0.0 6.7 0.7 6.0 0.6 0.0 0.3 0.0 0.1 0.2 0.6 20.4 0.0 1.3 0.0 0.0 0.1 32.0 0.0 0.0 0.8 0.3 0.5 1.2 8.3 0.0 20.4 0.3 0.5 0.6 2.3 0.0 0.1 20.8 2.2 6.1 0.3 13.8 0.0 0.3 0.0 0.0 24.7 5.8 1.7 1.8 18.8 0.0 30.9 16.1 2.6 39.1 8.5 0.3 0.4 0.0 4.5 7.5 0.1 0.0 0.2 1.7 0.4 6.6 0.7 6.6 0.1 1.0 0.2 1.0 0.1 18.6 0.5 0.0 0.1 GADD45A "DDIT1, GADD45" ENSG00000116717 "Growth arrest and DNA damage inducible alpha" P24522 1 67685201-67688334 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, Growth arrest" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 240.5" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 858.9;Basal prostatic cells: 2807.1;Glandular and luminal cells: 982.6;Urothelial cells: 1740.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 48.4" "Group enriched" "Detected in all" 5 "granulocytes: 48.4;T-cells: 18.6" "Cell line enhanced" "Detected in all" "HHSteC: 365.9;hTERT-HME1: 577.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053420 Supported "Nuclear speckles" NA Yes "Cluster 2: Granulocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Nuclear speckles" "HPA053420: AB_2682144" "unprognostic (1.36e-2)" "unprognostic (3.29e-2)" "unprognostic (9.58e-2)" "unprognostic (3.76e-3)" "unprognostic (5.81e-2)" "unprognostic (1.36e-2)" "unprognostic (1.57e-3)" "unprognostic (2.80e-3)" "unprognostic (1.42e-1)" "unprognostic (6.26e-2)" "unprognostic (3.43e-2)" "unprognostic (5.21e-2)" "prognostic favorable (8.06e-6)" "unprognostic (6.11e-2)" "unprognostic (2.89e-1)" "unprognostic (3.43e-3)" "unprognostic (1.93e-1)" 122.0 15.9 21.0 20.0 24.7 136.2 83.7 19.2 27.5 65.6 22.3 29.6 24.8 69.5 23.3 39.2 42.3 44.2 62.2 20.8 24.0 147.2 164.9 75.0 13.7 34.7 26.8 49.6 20.2 19.5 19.1 22.2 24.6 25.6 21.2 19.0 32.4 36.9 240.5 57.9 32.2 38.3 18.6 26.8 53.2 12.3 25.3 30.7 73.8 26.4 16.8 50.4 44.4 28.7 138.6 9.7 22.3 7.5 44.8 43.9 219.8 239.5 122.6 88.5 96.7 50.8 25.3 61.1 71.4 42.0 206.6 85.3 3.0 219.6 164.5 44.9 23.6 75.7 24.0 51.8 365.9 22.5 7.5 76.7 117.8 107.7 577.7 41.5 61.0 15.2 165.6 109.9 104.5 4.8 7.2 27.3 29.8 19.3 96.3 16.4 177.2 67.9 44.2 110.5 102.7 17.1 51.9 15.2 158.3 79.7 2.6 23.2 61.6 85.7 111.6 89.3 165.7 267.3 54.9 106.8 37.8 11.1 86.3 23.6 5.7 48.4 6.3 2.8 5.3 2.3 4.4 5.3 2.6 1.5 1.2 2.0 8.2 6.5 2.0 4.1 18.6 8.7 21.0 24.7 19.2 27.5 20.8 24.0 34.7 26.8 24.6 18.6 25.3 28.7 402.5 64.1 19.0 6.8 51.2 858.9 2807.1 273.2 225.3 45.1 56.7 100.6 190.5 47.1 155.8 103.0 10.4 24.6 85.1 175.3 236.7 264.4 1.6 410.7 250.6 176.6 131.7 116.2 6.1 253.6 117.8 177.0 87.7 982.6 44.5 18.9 74.6 110.1 18.6 26.9 7.0 99.6 122.1 23.5 290.6 4.0 38.2 94.7 158.3 7.5 273.2 30.3 12.3 6.6 1.0 367.3 202.0 64.7 116.8 786.2 101.4 530.0 135.1 72.8 52.6 136.0 201.6 3.7 18.8 365.2 390.8 17.6 139.5 88.6 70.3 1740.4 GAS1 ENSG00000180447 "Growth arrest specific 1" P54826 9 86944362-86947506 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Growth arrest" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 105.4" "Cell type enhanced" "Detected in many" "Fibroblasts: 127.1;Muller glia cells: 90.3;Skeletal myocytes: 213.7" "Cancer enhanced" "Detected in all" "ovarian cancer: 30.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 44.2;ASC diff: 29.3;BJ hTERT+: 59.8;HSkMC: 41.1;RH-30: 91.1" "Low region specificity" "Detected in all" "CAB024164, HPA036085, HPA066902" Approved Approved "Nuclear speckles" NA NA 27000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "Nuclear speckles" "CAB024164: AB_2107950, HPA036085: AB_2674932, HPA066902: AB_2685746" "unprognostic (2.78e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (1.55e-4)" "unprognostic (1.97e-2)" "unprognostic (6.15e-2)" "unprognostic (2.84e-2)" "unprognostic (6.46e-2)" "unprognostic (6.91e-2)" "unprognostic (3.32e-1)" "unprognostic (1.28e-3)" "unprognostic (2.25e-3)" "unprognostic (4.30e-2)" "prognostic unfavorable (1.96e-5)" "prognostic unfavorable (8.26e-4)" "unprognostic (6.73e-2)" "prognostic unfavorable (1.13e-5)" "unprognostic (3.59e-2)" 81.5 6.4 3.6 16.6 4.4 0.2 38.3 3.5 4.4 27.1 16.1 27.6 2.2 105.4 15.2 5.8 60.7 10.5 27.1 3.2 2.7 12.5 2.2 7.8 6.8 3.8 3.8 45.1 11.2 1.9 8.4 22.1 3.6 22.6 2.3 3.3 13.1 9.6 12.2 22.2 9.3 43.4 3.4 3.6 16.3 1.8 3.8 7.1 15.9 9.3 3.1 22.5 27.1 6.8 0.0 0.0 7.5 44.2 29.3 10.9 0.8 8.8 59.8 2.9 2.6 0.0 0.1 0.0 0.5 15.8 0.3 0.6 0.0 0.3 1.2 5.2 17.8 0.0 25.0 0.0 14.9 0.1 0.7 41.1 6.3 1.0 5.3 0.0 0.0 0.9 0.0 0.0 12.6 0.0 0.0 0.4 9.5 0.3 0.1 9.6 91.1 0.0 0.4 0.0 1.0 4.0 12.9 0.0 14.1 4.8 0.1 0.2 0.1 13.0 3.6 0.9 3.0 0.0 0.0 0.0 0.4 0.6 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 4.4 3.5 4.4 3.2 2.7 3.8 3.8 3.6 3.4 3.8 6.8 15.8 0.0 0.6 2.0 0.4 25.9 7.5 10.9 10.2 8.3 3.9 28.3 5.5 0.0 3.1 14.7 10.4 21.5 7.8 0.1 9.8 0.5 0.1 2.4 36.6 5.6 0.0 0.4 1.2 0.4 3.7 127.1 1.1 2.0 0.0 2.1 22.9 0.3 5.8 5.0 2.6 0.3 0.0 1.0 15.4 0.9 32.3 2.2 17.8 1.9 0.2 90.3 7.2 8.5 4.4 0.2 0.0 12.4 2.1 4.5 0.0 2.6 0.7 3.2 39.5 213.7 15.4 0.3 1.3 1.0 12.5 4.5 2.1 0.8 0.2 0.4 GCAT KBL ENSG00000100116 "Glycine C-acetyltransferase" O75600 22 37807905-37817176 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 140.2" "Cell type enhanced" "Detected in many" "Distal tubular cells: 80.3;Hepatocytes: 66.1;Proximal tubular cells: 163.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020460, HPA063924" Approved Supported "Nucleoplasm,Nuclear speckles,Mitochondria" Yes No "Cluster 20: T-cells - T-cell receptor" "Cluster 22: Non-specific - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Nuclear speckles, Mitochondria" "HPA020460: AB_1849548, HPA063924: " "unprognostic (1.61e-1)" "unprognostic (1.80e-2)" "unprognostic (8.38e-2)" "unprognostic (1.05e-1)" "unprognostic (1.10e-2)" "unprognostic (4.17e-2)" "unprognostic (2.40e-1)" "unprognostic (1.37e-2)" "unprognostic (3.56e-2)" "unprognostic (2.76e-3)" "unprognostic (1.12e-1)" "unprognostic (2.51e-1)" "unprognostic (1.36e-3)" "unprognostic (8.00e-2)" "unprognostic (1.97e-1)" "unprognostic (4.73e-3)" "unprognostic (3.99e-1)" 6.6 15.7 25.1 3.2 24.8 14.1 6.5 26.2 33.3 6.3 22.5 7.3 4.9 7.8 3.0 17.0 6.0 5.0 43.4 26.1 25.0 13.0 53.3 5.6 2.8 25.9 27.4 9.0 140.2 6.0 9.7 2.7 27.8 22.8 4.9 2.2 13.3 6.8 19.5 8.1 5.4 4.2 24.4 1.5 13.2 10.3 27.9 4.3 16.0 19.1 3.1 7.1 7.0 24.6 18.7 4.7 11.9 68.2 24.0 19.4 8.4 25.9 26.9 19.2 16.3 10.5 2.1 5.8 11.8 11.7 11.3 10.6 11.9 18.3 4.3 2.6 21.9 12.9 15.0 42.5 39.0 23.0 16.4 22.8 10.9 12.7 27.7 6.2 16.0 23.0 33.2 6.6 9.2 16.2 24.3 42.3 5.0 28.8 19.0 25.2 2.5 34.4 24.6 14.3 24.5 16.7 20.0 32.3 13.9 4.2 25.8 11.1 11.8 19.3 10.6 12.9 9.2 21.9 11.5 12.1 13.3 21.1 20.5 0.1 0.6 0.4 0.7 0.7 0.3 0.1 1.6 0.5 1.3 0.0 3.5 1.4 0.3 1.3 0.4 1.3 1.7 1.4 25.1 24.8 26.2 33.3 26.1 25.0 25.9 27.4 27.8 24.4 27.9 24.6 3.5 6.4 15.4 9.8 2.8 7.8 18.5 11.2 12.5 8.9 18.6 17.4 54.6 11.5 9.4 11.0 4.2 15.7 0.7 13.1 80.3 7.2 4.1 9.9 8.1 5.5 2.4 22.7 5.0 10.3 19.6 9.8 15.3 16.7 8.9 17.6 5.0 66.1 4.7 8.4 4.7 32.3 8.2 2.9 1.3 7.7 3.7 2.1 21.4 1.0 1.0 25.1 1.0 6.6 4.1 5.4 8.7 9.8 2.0 19.1 8.6 163.8 6.4 2.2 6.6 4.8 30.1 12.6 33.2 19.6 6.0 27.8 3.0 27.8 24.0 14.4 GCNT1 "C2GNT, NACGT2, NAGCT2" ENSG00000187210 "Glucosaminyl (N-acetyl) transferase 1" Q02742 9 76419850-76651203 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 49.9;parathyroid gland: 84.1;stomach 1: 39.0;thyroid gland: 21.5" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 93.8;Kupffer cells: 42.2;Proximal enterocytes: 40.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 21.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 46.2;HSkMC: 39.4;U-2197: 33.9" "Group enriched" "Detected in all" 6 "cerebellum: 7.6;olfactory bulb: 24.9" "Low region specificity" "Detected in all" "HPA003522, HPA003523, HPA031151" Uncertain Supported "Nuclear speckles" NA NA 84000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 18: U-2197 - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nuclear speckles" "HPA003522: , HPA003523: , HPA031151: AB_10602904" "unprognostic (3.14e-1)" "unprognostic (2.01e-1)" "unprognostic (2.19e-1)" "prognostic favorable (8.44e-4)" "unprognostic (5.53e-2)" "unprognostic (2.41e-1)" "unprognostic (1.65e-2)" "unprognostic (3.37e-2)" "unprognostic (2.40e-1)" "unprognostic (2.63e-1)" "unprognostic (1.90e-1)" "unprognostic (3.06e-1)" "unprognostic (3.02e-3)" "unprognostic (4.21e-1)" "unprognostic (2.00e-1)" "unprognostic (2.80e-1)" "prognostic unfavorable (4.96e-4)" 4.0 0.8 1.8 5.0 2.2 5.1 4.6 4.8 1.7 10.6 1.3 8.7 49.9 5.9 0.7 1.8 1.5 2.9 1.2 2.0 0.9 0.9 1.9 4.2 6.7 1.0 1.0 0.7 2.1 84.1 0.9 2.9 1.0 6.3 9.3 0.1 3.8 1.3 0.3 1.1 32.3 4.8 1.0 7.3 39.0 1.6 1.5 3.0 21.5 0.7 4.7 2.2 0.8 1.4 4.7 0.4 0.3 0.1 5.5 26.5 6.7 18.8 8.4 15.0 10.5 4.7 1.1 3.3 1.8 14.1 2.9 4.0 9.5 7.8 16.6 2.3 1.6 8.2 0.4 0.8 46.2 6.0 2.7 39.4 2.0 14.5 15.5 12.2 13.9 4.1 0.0 3.2 15.1 7.1 3.2 9.7 8.8 11.9 1.1 5.3 9.3 1.6 17.5 8.3 2.0 0.0 2.3 2.5 0.1 6.6 0.0 4.1 5.6 9.3 5.9 33.9 8.4 4.7 0.9 0.0 18.7 10.1 2.3 6.1 3.2 21.6 1.5 7.8 0.5 1.9 1.7 1.5 5.8 10.2 0.3 1.1 1.1 5.8 7.3 2.8 2.5 2.1 1.8 2.2 4.8 1.7 2.0 0.9 1.0 1.0 1.0 1.0 1.5 1.4 2.9 0.0 1.7 2.0 8.3 0.9 5.0 34.4 0.6 0.0 8.8 4.2 1.0 0.0 15.6 3.7 0.0 2.1 10.7 16.6 0.0 1.0 20.1 15.1 4.2 5.1 27.6 17.9 11.8 24.3 27.1 3.4 93.8 24.6 10.8 0.6 6.4 0.3 8.1 0.0 1.7 21.3 16.2 42.2 8.5 12.9 0.0 18.6 1.8 15.0 6.7 0.1 8.2 0.5 0.8 12.9 14.5 1.2 2.2 6.8 40.7 1.4 17.0 0.4 0.0 0.9 1.8 1.8 3.3 1.0 0.3 19.0 10.6 0.2 38.4 1.5 GNAQ "G-ALPHA-q, GAQ" ENSG00000156052 "G protein subunit alpha q" P50148 9 77716097-78031811 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" Transducer "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 556.6;Excitatory neurons: 405.6;Microglial cells: 394.4;Oligodendrocyte precursor cells: 338.3;Oligodendrocytes: 495.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 27.0" "Lineage enriched" "Detected in many" 6 "granulocytes: 27.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB010036, HPA048886" Uncertain Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA 800000 "Cluster 38: Basophils - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "Nuclear speckles" "Plasma membrane, Cytosol" "CAB010036: AB_631536, HPA048886: AB_2680544" "unprognostic (2.10e-1)" "unprognostic (8.53e-2)" "unprognostic (1.45e-1)" "unprognostic (4.37e-2)" "unprognostic (1.87e-1)" "unprognostic (6.83e-3)" "unprognostic (1.05e-1)" "unprognostic (3.84e-2)" "unprognostic (2.46e-1)" "unprognostic (2.16e-1)" "unprognostic (1.85e-1)" "unprognostic (1.44e-1)" "prognostic favorable (1.11e-7)" "unprognostic (1.90e-1)" "unprognostic (3.13e-1)" "unprognostic (1.05e-1)" "unprognostic (2.01e-1)" 23.5 21.3 37.2 18.8 42.2 43.8 20.1 35.8 51.3 21.1 19.3 30.3 14.5 23.7 18.7 23.2 16.9 20.1 8.6 51.0 38.5 20.9 22.0 31.1 9.9 40.5 42.7 22.4 14.6 16.3 12.5 21.7 39.9 21.2 27.2 10.4 16.8 25.7 10.5 8.9 16.8 27.4 42.4 11.3 27.9 11.5 45.5 19.7 23.1 11.8 9.1 23.5 13.8 48.5 30.6 34.1 29.8 32.0 34.9 35.5 42.8 40.7 29.7 16.6 20.6 10.5 24.1 0.1 32.0 35.5 24.5 48.5 22.5 23.4 20.6 1.1 12.5 83.0 29.0 21.4 31.4 51.8 30.0 24.3 28.0 33.9 32.5 34.3 42.7 70.3 14.8 0.2 29.5 38.5 58.8 31.0 24.0 46.5 4.7 22.0 36.5 0.3 37.8 64.5 33.1 49.6 29.3 23.3 30.5 27.5 22.2 18.3 55.0 29.2 1.9 41.9 24.0 0.2 0.1 0.3 20.3 28.9 32.0 27.0 2.5 5.7 0.8 2.2 1.7 0.9 2.0 1.1 2.8 0.9 2.1 1.7 8.9 3.6 4.5 3.2 2.2 1.5 37.2 42.2 35.8 51.3 51.0 38.5 40.5 42.7 39.9 42.4 45.5 48.5 117.7 176.3 97.5 556.6 4.8 47.3 38.4 42.7 39.3 34.0 75.6 54.5 6.0 58.6 48.3 77.3 16.7 47.4 33.4 137.0 7.9 36.2 18.9 57.5 64.2 107.3 92.3 58.0 405.6 39.7 53.2 51.7 70.8 76.0 50.7 40.2 98.6 64.0 53.7 82.4 242.0 92.5 30.5 139.5 173.9 11.1 39.4 128.8 48.0 394.4 114.6 40.5 8.2 338.3 495.2 54.2 60.7 52.3 6.2 70.5 52.9 45.4 67.0 5.0 26.3 62.3 40.8 5.6 13.2 46.3 21.6 29.0 25.0 45.2 75.4 70.1 GNB5 GB5 ENSG00000069966 "G protein subunit beta 5" O14775 15 52115100-52191392 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" Transducer "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 120.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 267.5;Cone photoreceptor cells: 279.4;Muller glia cells: 206.9;Rod photoreceptor cells: 296.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032353, HPA041942, HPA044198" Uncertain Approved "Nuclear speckles,Centrosome,Rods & Rings" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 9: Photoreceptor cells - Phototransduction" "Nuclear speckles" "Centrosome, Rods & Rings" "CAB032353: AB_2263274, HPA041942: AB_10794309, HPA044198: AB_2678853" "unprognostic (2.38e-2)" "unprognostic (3.58e-1)" "unprognostic (1.97e-3)" "prognostic favorable (1.47e-6)" "unprognostic (6.15e-2)" "unprognostic (1.37e-2)" "unprognostic (2.57e-2)" "unprognostic (2.63e-2)" "unprognostic (1.54e-1)" "unprognostic (2.44e-1)" "unprognostic (1.67e-3)" "unprognostic (2.10e-1)" "prognostic favorable (3.32e-11)" "unprognostic (1.40e-3)" "unprognostic (8.12e-3)" "unprognostic (3.55e-3)" "unprognostic (1.52e-1)" 11.2 14.5 20.7 11.8 22.5 5.4 12.7 26.7 28.3 27.1 8.7 18.8 5.9 28.3 17.2 11.8 26.8 20.8 22.8 21.9 25.6 36.3 18.8 8.9 21.9 22.5 13.6 49.4 18.9 40.6 25.9 5.7 23.4 16.6 5.5 120.0 11.2 25.5 2.5 8.7 13.1 17.4 9.4 13.5 11.1 15.7 23.6 14.9 21.7 4.7 19.9 20.8 18.1 15.1 18.9 47.6 12.9 23.1 21.5 26.9 12.5 36.1 34.8 31.4 34.0 13.3 13.9 32.6 11.0 29.7 52.9 27.0 23.1 34.3 23.6 25.5 17.5 21.8 60.7 15.6 25.7 11.0 75.8 25.0 28.3 25.2 9.3 33.3 19.9 28.2 1.7 29.9 34.8 33.6 17.6 31.4 12.1 6.3 20.9 23.4 44.9 40.0 22.4 56.7 20.8 18.0 34.6 3.2 28.7 15.8 11.1 33.9 49.5 28.1 30.7 32.2 36.8 18.9 39.0 35.7 58.9 26.6 46.2 10.1 3.8 0.4 21.4 3.8 17.6 41.5 27.2 25.5 10.1 43.8 25.2 21.9 2.2 23.6 3.2 20.6 42.5 18.7 20.7 22.5 26.7 28.3 21.9 25.6 22.5 13.6 23.4 9.4 23.6 15.1 15.9 22.4 23.8 17.0 79.5 19.2 22.8 15.5 21.1 267.5 20.7 27.9 18.3 34.3 21.8 18.4 279.4 4.8 27.1 2.7 19.6 28.9 1.8 28.3 28.7 17.7 19.7 6.1 72.8 18.5 24.8 23.5 8.6 59.9 29.8 20.1 13.6 10.0 3.8 111.0 67.7 1.7 14.2 6.2 15.2 4.6 39.7 20.5 19.6 8.4 4.0 206.9 15.5 22.1 7.8 19.1 5.1 116.9 18.7 10.9 0.8 36.3 24.6 296.5 46.0 16.6 23.9 2.1 6.2 10.8 16.3 2.9 31.9 20.1 2.8 17.8 GPATCH2 "CT110, FLJ10252, GPATC2, Pfa1, PPP1R30" ENSG00000092978 "G-patch domain containing 2" Q9NW75 1 217426992-217631090 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 171.0;Rod photoreceptor cells: 144.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027181, HPA027322" Uncertain Supported "Nuclear speckles" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 30: Epithelial cell lines - Translation" "Cluster 9: Photoreceptor cells - Phototransduction" "Nuclear speckles" "HPA027181: AB_10602601, HPA027322: AB_1848645" "unprognostic (3.27e-1)" "unprognostic (2.66e-1)" "unprognostic (1.29e-1)" "unprognostic (2.04e-1)" "unprognostic (3.27e-2)" "unprognostic (5.13e-2)" "unprognostic (6.50e-2)" "unprognostic (1.28e-1)" "unprognostic (6.24e-3)" "unprognostic (2.46e-2)" "unprognostic (1.53e-1)" "unprognostic (2.03e-1)" "prognostic unfavorable (9.99e-6)" "unprognostic (3.52e-1)" "unprognostic (2.50e-2)" "unprognostic (1.53e-2)" "unprognostic (5.41e-2)" 4.1 4.2 3.5 4.1 4.0 3.2 7.1 3.0 4.8 5.9 6.3 4.3 4.9 6.5 5.9 5.5 5.0 6.1 3.5 4.3 5.1 5.2 4.9 4.2 5.1 2.9 3.2 4.8 3.9 6.9 4.4 6.3 3.1 6.9 4.6 5.7 3.7 5.3 6.6 4.4 4.8 5.1 3.2 4.8 4.8 6.2 4.5 6.3 6.6 2.9 5.6 6.1 4.1 3.8 8.4 9.4 9.9 7.8 8.6 8.7 8.2 7.7 9.4 10.5 9.9 8.3 10.6 8.9 7.6 6.7 6.5 9.7 11.2 9.1 12.2 6.6 6.4 5.9 7.9 5.3 10.6 9.0 6.7 7.7 13.0 12.3 20.0 9.1 7.3 9.8 14.7 0.1 7.7 7.9 12.2 6.4 18.0 6.7 10.2 5.9 22.7 10.7 7.4 17.9 11.6 16.5 13.7 12.5 10.7 15.5 11.7 8.7 7.5 9.8 6.8 13.9 7.2 9.0 6.8 8.4 7.4 5.9 7.1 4.1 3.1 1.1 2.6 1.9 1.8 2.6 3.0 1.8 3.4 2.8 2.7 2.4 0.4 2.7 2.9 5.0 2.9 1.5 3.5 4.0 3.0 4.8 4.3 5.1 2.9 3.2 3.1 3.2 4.5 3.8 17.5 12.8 15.9 43.8 19.4 15.6 16.1 13.4 14.8 55.4 27.2 27.9 14.4 21.5 15.3 18.4 171.0 20.8 24.5 22.4 13.7 20.4 62.6 41.3 36.4 20.5 20.8 12.0 113.1 18.0 22.2 23.0 19.4 24.0 9.5 32.9 20.7 12.4 15.7 50.5 60.5 21.5 18.3 9.2 9.2 22.8 19.9 16.6 5.4 39.4 17.2 27.7 28.8 46.3 47.1 15.0 17.2 23.0 24.5 17.5 17.9 18.1 22.3 144.2 19.7 36.8 20.2 53.3 23.8 12.9 19.5 21.6 20.0 41.4 23.1 19.0 GPATCH8 "GPATC8, KIAA0553" ENSG00000186566 "G-patch domain containing 8" Q9UKJ3 17 44395281-44503430 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Excitatory neurons: 312.1;Inhibitory neurons: 287.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044380 Approved Approved "Nuclear speckles,Mitochondria" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear speckles" Mitochondria "HPA044380: AB_10965696" "unprognostic (3.37e-1)" "unprognostic (5.90e-2)" "unprognostic (1.27e-1)" "unprognostic (1.37e-1)" "unprognostic (6.07e-3)" "unprognostic (2.13e-2)" "unprognostic (5.86e-3)" "unprognostic (2.25e-1)" "unprognostic (1.38e-1)" "unprognostic (6.84e-3)" "unprognostic (8.47e-2)" "unprognostic (6.99e-2)" "unprognostic (2.04e-2)" "unprognostic (1.50e-1)" "unprognostic (9.91e-2)" "unprognostic (7.58e-2)" "unprognostic (2.49e-1)" 10.5 9.2 12.0 11.3 13.3 18.3 11.0 15.0 14.0 10.6 9.3 8.9 11.1 14.5 11.8 9.4 11.1 8.8 8.9 11.8 12.5 9.0 7.0 10.7 15.7 12.9 12.9 17.3 8.0 14.4 0.4 13.1 12.7 9.5 10.4 30.1 9.3 10.2 33.4 15.5 11.0 12.5 12.1 13.1 8.8 10.8 13.0 20.8 11.0 13.8 15.4 9.8 0.8 13.5 22.0 12.8 22.8 18.9 17.5 20.2 23.1 16.7 21.1 18.3 19.2 19.0 13.9 31.1 10.9 23.7 15.8 16.7 23.3 19.3 27.2 25.7 20.8 26.5 15.5 22.5 20.9 25.7 20.3 22.9 20.5 20.9 27.2 18.4 20.2 19.4 20.1 18.7 16.8 10.0 33.7 9.9 16.0 12.5 16.2 27.1 25.8 21.7 16.0 10.6 15.9 19.3 16.6 10.6 20.9 27.0 13.9 17.3 22.5 18.0 12.6 19.3 23.4 20.1 17.9 29.2 16.8 14.1 19.3 8.2 6.1 4.9 9.4 6.0 8.7 8.6 8.2 7.8 6.5 7.1 7.5 7.3 4.6 10.3 13.6 8.0 4.1 5.2 12.0 13.3 15.0 14.0 11.8 12.5 12.9 12.9 12.7 12.1 13.0 13.5 38.8 22.4 32.5 148.5 64.6 48.7 53.1 52.0 47.8 72.7 28.8 22.7 40.5 30.0 46.0 25.8 123.0 42.4 76.6 25.2 9.8 32.8 19.6 38.7 63.3 38.8 38.8 50.1 312.1 24.5 39.3 48.4 23.9 56.5 42.4 44.6 44.3 19.4 23.0 146.4 287.3 20.3 36.7 36.2 42.3 7.6 63.0 38.6 23.2 108.7 42.5 43.5 161.7 172.9 204.1 34.7 24.7 43.2 58.1 45.3 30.2 14.6 29.8 125.3 52.6 68.6 51.2 93.1 74.2 33.7 46.9 53.4 69.8 43.1 25.4 56.8 GPN3 "ATPBD1C, MGC14560" ENSG00000111231 "GPN-loop GTPase 3" Q9UHW5 12 110452486-110469268 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 187.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039764, HPA047793" Uncertain Approved "Nuclear speckles,Cytosol" Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" Cytosol "HPA039764: AB_2676669, HPA047793: AB_2680157" "unprognostic (1.68e-3)" "unprognostic (1.11e-2)" "unprognostic (9.82e-2)" "unprognostic (4.96e-2)" "unprognostic (2.09e-1)" "unprognostic (3.27e-3)" "prognostic unfavorable (3.98e-5)" "unprognostic (5.50e-2)" "unprognostic (4.45e-2)" "unprognostic (2.70e-1)" "unprognostic (1.24e-1)" "unprognostic (3.56e-2)" "prognostic favorable (2.65e-6)" "unprognostic (5.81e-2)" "unprognostic (2.85e-1)" "unprognostic (1.62e-1)" "unprognostic (2.27e-1)" 25.6 18.9 10.4 16.3 11.7 15.4 24.4 12.9 12.9 15.7 11.6 15.6 8.1 17.8 15.2 16.3 18.5 13.8 34.2 10.0 11.0 31.4 32.1 16.9 22.9 12.2 11.2 23.3 19.9 29.2 11.1 21.3 12.8 22.2 13.1 23.4 24.2 18.0 47.9 11.1 10.6 19.5 13.0 16.2 15.6 41.3 10.9 18.1 21.2 51.1 18.1 17.6 13.8 14.9 42.3 65.8 43.2 42.8 47.5 30.1 57.6 57.1 34.1 62.2 50.3 59.7 24.6 81.5 38.5 31.0 46.0 37.9 54.2 50.5 83.9 46.9 50.6 47.7 33.8 50.5 33.2 75.2 42.2 32.2 31.4 61.1 39.5 34.9 45.6 67.0 82.1 17.9 44.3 28.2 69.8 142.8 53.4 58.6 64.8 23.5 59.9 62.2 39.3 37.8 34.7 34.8 57.7 39.0 49.9 55.0 66.7 87.7 25.4 51.6 38.0 51.3 66.6 24.7 68.0 85.1 38.2 68.5 60.3 41.0 54.4 79.4 30.0 71.9 32.8 46.5 32.0 34.2 51.1 47.9 40.5 26.9 27.4 28.4 75.3 62.5 30.1 41.6 10.4 11.7 12.9 12.9 10.0 11.0 12.2 11.2 12.8 13.0 10.9 14.9 23.8 25.6 34.5 3.3 24.5 29.8 49.3 57.9 15.9 18.8 28.8 32.5 43.8 20.0 36.0 33.1 14.6 62.4 26.6 3.8 107.6 30.4 111.1 24.9 24.6 20.8 8.3 26.9 4.3 21.3 74.0 25.4 8.2 21.5 31.0 18.6 18.2 38.1 94.7 21.9 5.6 9.1 40.7 19.1 17.7 22.6 19.9 33.2 16.0 14.0 39.6 25.7 19.6 3.5 6.4 22.4 11.0 23.7 20.9 55.5 5.3 72.1 34.2 33.0 26.3 31.0 35.3 187.2 77.6 20.8 25.4 46.7 19.2 22.1 13.7 40.2 GRAMD2A GRAMD2 ENSG00000175318 "GRAM domain containing 2A" Q8IUY3 15 72159806-72197787 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 35.9;placenta: 48.7" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 70.5;Cytotrophoblasts: 106.2;Extravillous trophoblasts: 29.5;Syncytiotrophoblasts: 147.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "BEWO: 165.5;SK-BR-3: 75.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA029435 Uncertain Approved "Nucleoli,Nuclear speckles,Cytosol" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoli, Nuclear speckles" Cytosol "HPA029435: AB_10601811" "unprognostic (5.70e-2)" "unprognostic (7.55e-2)" "unprognostic (3.33e-1)" "unprognostic (1.24e-1)" "unprognostic (9.51e-3)" "unprognostic (2.95e-1)" "unprognostic (9.96e-2)" "unprognostic (3.90e-3)" "unprognostic (2.80e-1)" "unprognostic (1.96e-1)" "unprognostic (2.62e-1)" "unprognostic (5.77e-2)" "unprognostic (4.45e-1)" "unprognostic (2.35e-1)" "unprognostic (6.33e-2)" "prognostic unfavorable (7.01e-4)" "unprognostic (7.29e-2)" 0.0 0.0 2.1 0.5 1.7 0.0 10.2 2.0 1.3 1.9 2.1 1.2 1.0 0.4 35.9 1.1 5.8 0.3 0.1 2.2 3.9 3.2 0.0 15.0 0.4 6.5 13.1 0.1 0.5 0.1 0.7 48.7 10.1 1.3 0.8 0.9 2.1 5.2 0.0 2.5 3.3 0.2 2.6 0.2 0.8 0.4 3.0 0.2 8.9 0.0 0.4 0.3 0.7 2.0 2.1 0.0 0.1 0.0 0.0 0.0 165.5 0.0 0.0 0.0 0.0 0.2 0.4 0.2 0.6 0.0 0.0 1.2 0.0 10.0 0.2 0.0 0.2 0.3 0.1 0.0 1.2 0.0 0.0 0.1 2.1 0.0 7.5 0.0 0.2 0.0 0.1 0.0 0.0 1.0 0.1 0.0 0.5 0.6 0.0 0.1 0.0 0.1 0.2 0.1 1.7 0.1 0.3 75.8 0.1 5.5 3.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 1.7 2.0 1.3 2.2 3.9 6.5 13.1 10.1 2.6 3.0 2.0 0.1 70.5 15.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 5.3 0.0 0.0 7.4 3.7 0.0 106.2 0.1 0.0 0.0 0.1 0.0 14.0 0.2 0.2 0.0 0.0 0.0 0.0 29.5 0.8 0.0 0.7 1.3 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.5 10.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 147.1 0.3 0.1 0.0 0.0 GRK5 GPRK5 ENSG00000198873 "G protein-coupled receptor kinase 5" P34947 10 119207571-119459745 "Enzymes, Predicted intracellular proteins" "Apoptosis, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 57.7;Microglial cells: 56.2;Sertoli cells: 59.2;Smooth muscle cells: 46.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 32.1;HUVEC TERT2: 24.9;OE19: 25.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025579, HPA046838" Approved Supported "Nuclear membrane,Nuclear speckles,Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 21: OE19 - Mitochondria" "Cluster 50: Fibroblasts - ECM organization" "Nuclear membrane, Nuclear speckles" "Plasma membrane" "CAB025579: , HPA046838: AB_2679833" "unprognostic (1.09e-1)" "unprognostic (3.47e-1)" "unprognostic (1.19e-1)" "unprognostic (6.02e-2)" "unprognostic (6.56e-2)" "unprognostic (3.74e-2)" "unprognostic (4.62e-2)" "unprognostic (3.69e-1)" "unprognostic (4.11e-1)" "unprognostic (1.06e-1)" "unprognostic (3.70e-1)" "unprognostic (2.32e-1)" "prognostic unfavorable (2.38e-7)" "unprognostic (1.10e-1)" "unprognostic (3.27e-2)" "unprognostic (1.55e-2)" "unprognostic (1.90e-2)" 38.4 18.0 4.2 5.9 5.0 2.7 24.6 5.0 4.6 18.8 3.5 26.3 10.0 21.1 3.5 12.6 19.6 5.7 48.8 4.0 5.1 14.2 12.9 65.6 7.8 3.9 3.6 35.0 4.7 21.3 13.3 8.3 3.9 14.1 4.9 1.0 7.8 4.0 11.9 11.5 25.8 7.3 3.3 37.0 27.5 4.1 4.9 6.2 19.6 9.7 6.8 19.4 18.1 3.5 3.7 2.3 5.4 5.7 11.8 11.0 1.6 7.1 32.1 4.1 2.3 1.7 5.4 3.9 1.6 11.1 7.5 0.9 2.3 7.7 2.7 15.4 2.0 0.7 4.6 7.0 8.2 0.2 2.0 1.5 1.1 8.5 1.2 5.2 24.9 2.4 0.4 3.7 1.5 0.7 3.8 3.5 0.8 25.8 5.2 1.3 0.8 0.9 0.6 1.5 1.8 4.9 2.4 1.1 7.0 3.0 0.1 0.9 7.8 2.3 1.6 14.6 2.8 0.9 4.4 2.4 4.9 4.4 2.4 0.4 1.5 2.9 2.0 1.4 0.1 3.8 3.0 1.6 0.9 4.0 4.5 2.0 2.1 0.1 0.5 0.0 4.0 1.7 4.2 5.0 5.0 4.6 4.0 5.1 3.9 3.6 3.9 3.3 4.9 3.5 32.6 57.7 3.7 3.6 19.7 1.7 0.7 0.5 1.2 3.9 2.3 2.0 19.4 0.0 1.3 3.7 0.0 3.7 13.3 0.4 0.0 1.1 18.7 0.4 5.1 28.4 4.8 0.0 17.7 3.1 15.8 35.7 18.8 1.0 4.5 7.8 24.7 2.2 4.4 1.7 36.5 0.8 6.1 15.5 6.3 4.9 4.4 14.2 7.2 56.2 3.6 0.0 19.6 14.1 5.7 2.4 1.2 4.5 10.2 0.7 4.9 0.6 0.8 0.9 59.2 18.2 46.5 1.3 2.1 0.7 2.4 13.1 14.1 4.6 0.5 0.9 GSC ENSG00000133937 "Goosecoid homeobox" P56915 14 94768223-94770113 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 3.8;breast: 6.8" "Cell type enhanced" "Detected in some" "Adipocytes: 3.5;Breast myoepithelial cells: 2.2;Ductal cells: 3.0;Exocrine glandular cells: 2.4;Fibroblasts: 9.2;Langerhans cells: 2.3;Skeletal myocytes: 2.6;Smooth muscle cells: 4.6" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 9 "hypothalamus: 1.4" "Immune cell enriched" "Detected in single" 8 "gdT-cell: 3.6" "Lineage enriched" "Detected in single" 18 "T-cells: 3.6" "Cell line enhanced" "Detected in some" "AN3-CA: 1.3;HEK 293: 2.0;MCF7: 3.2;REH: 3.3;SH-SY5Y: 3.5;T-47d: 2.5;U-251 MG: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "CAB079923, CAB079924" Supported "Nucleoplasm,Nuclear speckles,Actin filaments" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 14: REH - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nuclear speckles" "Actin filaments" "CAB079923: , CAB079924: " "unprognostic (2.11e-2)" "unprognostic (1.04e-1)" "unprognostic (3.15e-2)" "unprognostic (5.11e-2)" "unprognostic (2.49e-1)" "unprognostic (3.70e-3)" "unprognostic (1.82e-3)" "unprognostic (3.87e-2)" "unprognostic (3.41e-1)" "unprognostic (2.74e-1)" "unprognostic (1.39e-1)" "unprognostic (2.28e-1)" "unprognostic (5.18e-10)" "unprognostic (4.96e-2)" "unprognostic (1.31e-1)" "unprognostic (1.52e-1)" "unprognostic (1.16e-1)" 3.8 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.1 0.4 0.1 0.1 0.2 0.0 0.1 0.4 0.0 0.5 0.0 1.4 0.1 0.0 0.0 0.3 0.1 0.1 0.1 0.6 0.1 0.4 0.0 0.0 0.7 0.0 0.0 0.9 0.5 1.2 0.8 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.2 1.6 2.2 0.1 0.3 0.2 0.0 0.0 0.2 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.3 0.0 0.0 0.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 3.2 0.2 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.1 2.5 0.0 0.0 0.0 0.6 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.1 0.0 0.2 0.4 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.1 0.0 0.0 0.1 0.0 3.5 0.0 0.0 0.0 0.1 0.6 0.3 0.0 0.0 0.0 1.0 2.2 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 3.0 0.1 0.3 0.1 0.4 0.0 0.0 0.0 2.4 0.0 9.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 0.0 0.2 0.0 0.0 0.6 0.0 1.0 0.0 0.0 0.7 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 2.6 4.6 0.0 1.2 0.0 0.9 0.0 0.4 0.0 0.0 0.1 GTF2H2 "BTF2, BTF2P44, p44, T-BTF2P44, TFIIH" ENSG00000145736 "General transcription factor IIH subunit 2" Q13888 5 71032670-71067689 "Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Daudi: 18.5;RPTEC TERT1: 19.1" HPA047001 Supported "Nuclear speckles" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nuclear speckles" "HPA047001: AB_2679899" "unprognostic (7.40e-3)" "unprognostic (4.71e-1)" "unprognostic (6.31e-2)" "unprognostic (2.99e-1)" "unprognostic (1.62e-1)" "unprognostic (3.07e-1)" "unprognostic (1.29e-2)" "unprognostic (4.69e-2)" "unprognostic (2.08e-1)" "unprognostic (2.22e-3)" "unprognostic (3.74e-1)" "unprognostic (3.06e-1)" "unprognostic (3.67e-2)" "unprognostic (3.93e-2)" "unprognostic (2.43e-1)" "unprognostic (1.87e-3)" "unprognostic (1.62e-1)" 3.1 2.9 0.6 1.1 0.7 1.1 2.8 1.1 1.7 3.9 0.4 4.6 0.2 3.8 2.0 2.6 3.4 1.2 2.7 0.6 0.9 3.6 3.4 2.8 4.8 0.8 0.9 3.4 4.3 1.1 2.6 0.9 1.0 2.3 1.0 1.7 2.8 0.6 3.5 1.9 2.9 5.1 0.6 2.8 2.9 3.7 0.9 1.4 3.5 0.0 0.3 2.6 3.0 1.2 4.8 0.0 4.2 0.0 11.0 12.8 13.9 0.5 0.2 0.3 0.7 12.0 0.4 18.5 8.4 10.2 6.1 3.1 0.6 0.1 0.3 15.0 14.0 8.7 0.2 0.9 12.3 0.4 0.0 0.0 2.7 0.4 0.0 2.4 0.0 0.1 0.2 3.3 0.0 7.3 5.6 6.0 0.1 0.1 0.0 6.6 2.6 11.1 19.1 0.0 0.4 4.6 12.1 1.4 11.5 0.3 7.7 8.0 4.2 5.3 1.1 0.7 8.7 0.2 0.8 4.7 0.1 0.8 10.1 0.2 0.5 0.2 0.6 0.3 0.2 0.5 0.7 0.5 0.3 0.8 0.7 0.5 2.1 0.3 0.3 0.3 0.0 0.3 0.6 0.7 1.1 1.7 0.6 0.9 0.8 0.9 1.0 0.6 0.9 1.2 6.9 16.0 27.0 6.8 17.6 16.6 23.5 17.5 7.4 23.3 14.9 8.1 16.7 28.6 18.7 12.9 39.6 37.3 9.6 8.4 46.9 19.1 5.4 17.0 17.7 12.6 12.0 15.2 10.0 20.5 17.5 14.6 7.1 17.7 6.3 25.5 14.6 12.5 15.0 25.2 10.2 5.9 14.2 15.0 9.9 7.0 24.2 11.0 14.2 4.7 7.9 10.6 9.2 9.0 11.0 16.7 7.5 13.2 14.6 23.7 8.9 22.5 22.7 39.7 26.3 14.1 12.5 60.3 55.9 6.9 12.5 9.6 15.3 15.5 9.1 18.7 GTF2H2C ENSG00000183474 "GTF2H2 family member C" Q6P1K8 5 69560191-69595221 "Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 10.1" "Lineage enriched" "Detected in all" 4 "granulocytes: 10.1" "Cell line enhanced" "Detected in many" "U-266/84: 37.5" HPA047001 Approved "Nuclear speckles" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "HPA047001: AB_2679899" "unprognostic (3.70e-1)" "unprognostic (3.46e-2)" "unprognostic (2.11e-2)" "unprognostic (1.95e-1)" "unprognostic (5.97e-2)" "unprognostic (4.33e-2)" "unprognostic (8.59e-3)" "unprognostic (5.34e-2)" "unprognostic (7.12e-2)" "unprognostic (6.03e-2)" "unprognostic (6.08e-2)" "unprognostic (1.56e-1)" "unprognostic (1.86e-1)" "unprognostic (7.52e-2)" "unprognostic (2.68e-1)" "unprognostic (2.40e-3)" "unprognostic (2.55e-1)" 7.4 6.9 3.0 4.0 3.6 2.9 7.2 4.6 4.4 9.0 2.0 8.0 1.4 8.2 3.0 5.4 8.2 1.7 6.1 3.2 3.2 13.0 11.3 8.3 4.0 3.7 3.5 8.6 10.6 2.8 6.4 1.5 4.0 6.0 2.0 4.4 6.8 2.3 6.0 4.9 7.2 3.7 2.4 7.9 7.2 9.8 3.3 3.8 9.9 1.3 1.1 7.1 6.8 6.8 8.0 5.8 4.6 5.7 2.7 3.9 6.5 13.2 5.1 8.7 10.0 8.6 4.8 19.7 15.3 4.0 3.1 3.2 6.9 7.5 13.5 20.2 11.0 21.8 4.7 9.0 4.3 13.6 6.7 1.5 2.0 4.7 3.9 3.5 2.7 8.5 16.1 10.5 0.8 8.2 17.8 6.5 7.2 0.7 4.3 6.5 19.5 19.0 10.5 7.5 6.4 13.0 17.9 4.8 9.3 3.8 6.4 8.7 12.7 7.3 4.5 5.2 18.0 7.4 37.5 14.7 7.4 16.6 13.3 10.1 1.6 2.1 0.9 1.4 1.7 1.5 1.0 1.6 1.3 1.7 1.2 2.4 5.0 1.5 1.2 1.4 1.8 1.2 3.0 3.6 4.6 4.4 3.2 3.2 3.7 3.5 4.0 2.4 3.3 6.8 4.9 9.6 10.9 6.8 14.3 3.6 4.9 8.6 6.8 10.6 7.5 3.9 8.2 14.3 10.4 14.7 12.5 4.9 4.9 5.9 9.8 7.1 16.2 15.7 10.3 6.3 2.4 12.4 9.6 5.7 2.9 8.1 8.6 15.4 0.0 7.7 7.9 6.9 4.3 18.5 10.5 4.1 14.2 6.3 3.3 17.8 9.0 7.6 3.6 5.6 3.5 6.5 13.4 5.5 9.8 5.9 4.0 11.7 8.7 6.1 5.8 14.2 10.8 14.6 0.0 3.2 7.1 32.5 23.5 7.2 4.1 1.4 7.1 6.7 5.4 7.4 GTF2H4 "P52, TFB2, TFIIH" ENSG00000213780 "General transcription factor IIH subunit 4" Q92759 6 30908207-30914106 "Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 12.5;Gastric mucus-secreting cells: 9.7;granulocytes: 7.0;Plasma cells: 9.2;Squamous epithelial cells: 13.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA074336 Supported "Nuclear speckles" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nuclear speckles" "HPA074336: AB_2686679" "unprognostic (7.05e-2)" "unprognostic (1.79e-1)" "unprognostic (3.07e-1)" "unprognostic (4.79e-4)" "unprognostic (7.42e-2)" "unprognostic (1.11e-1)" "unprognostic (5.54e-2)" "unprognostic (1.58e-1)" "unprognostic (1.84e-1)" "unprognostic (2.36e-2)" "unprognostic (5.66e-4)" "unprognostic (7.74e-3)" "prognostic unfavorable (4.08e-4)" "unprognostic (1.22e-1)" "unprognostic (9.53e-2)" "unprognostic (6.06e-2)" "unprognostic (2.07e-2)" 12.6 11.1 5.4 6.6 6.6 4.7 11.4 6.2 7.0 12.8 4.8 12.0 1.8 12.8 1.9 14.4 10.6 2.2 9.3 5.6 6.3 14.6 21.5 10.1 5.6 5.2 5.8 12.2 11.0 6.8 13.4 3.5 4.9 10.5 4.0 1.1 8.6 3.5 13.2 9.7 10.4 1.9 6.0 11.9 12.4 11.9 6.3 8.7 13.5 3.8 3.7 11.7 11.7 8.1 20.5 15.0 15.9 16.5 16.0 11.6 17.7 3.3 5.3 5.8 9.6 14.9 9.1 12.3 8.0 21.1 11.1 16.6 10.7 21.4 10.6 18.6 2.5 10.0 11.5 13.8 10.1 0.0 17.0 18.5 20.5 9.8 0.0 10.3 6.1 9.1 35.2 11.3 11.4 25.0 22.5 16.9 18.5 10.4 6.1 28.5 0.0 11.8 20.7 11.4 9.2 4.5 0.8 11.5 8.8 9.8 16.2 13.7 6.8 15.5 21.5 16.4 28.6 11.1 13.1 9.3 8.9 16.8 7.0 1.8 1.1 0.9 0.8 1.2 0.3 1.3 1.2 1.3 2.5 0.6 1.2 2.2 0.0 1.1 0.6 1.2 2.1 0.3 5.4 6.6 6.2 7.0 5.6 6.3 5.2 5.8 4.9 6.0 6.3 8.1 0.6 0.0 0.0 4.2 4.0 0.4 0.1 0.4 12.5 0.7 1.1 0.8 0.0 1.5 0.1 0.0 2.1 0.4 0.5 0.4 1.9 0.6 0.1 1.1 1.0 1.8 0.0 4.2 4.6 0.6 0.4 1.4 9.7 1.0 7.0 0.8 0.7 1.1 0.3 0.0 3.3 0.0 0.0 1.2 1.2 0.0 0.9 1.5 1.8 1.9 0.3 0.5 0.0 3.5 2.8 0.0 1.2 0.7 9.2 0.1 0.1 0.9 0.8 0.3 0.0 0.4 1.9 1.4 0.4 13.8 1.0 0.3 3.5 0.4 0.6 0.1 H1-4 "H1.4, H1e, H1F4, H1s-4, HIST1H1E" ENSG00000168298 "H1.4 linker histone, cluster member" P10412 6 26156329-26157115 "Disease related genes, Predicted intracellular proteins" DNA-binding "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "bone marrow: 52.3;brain: 53.8" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 11.2;Cytotrophoblasts: 8.0;dendritic cells: 18.6;Extravillous trophoblasts: 11.3;Hofbauer cells: 7.7;Plasma cells: 6.7;Syncytiotrophoblasts: 7.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 53.8" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 10.5;U-266/70: 12.5;U-266/84: 15.1;U-87 MG: 12.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011506, HPA055907" Supported Supported "Nuclear speckles" NA Yes 8300000 "Cluster 6: Non-specific - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 16: U-266 - Nucleosome" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles" "CAB011506: AB_470256, HPA055907: AB_2682966" "unprognostic (6.96e-2)" "unprognostic (1.25e-1)" "unprognostic (3.06e-2)" "unprognostic (1.86e-1)" "unprognostic (9.62e-2)" "unprognostic (1.04e-2)" "unprognostic (5.78e-3)" "unprognostic (2.31e-2)" "unprognostic (1.24e-1)" "unprognostic (1.00e-1)" "unprognostic (1.20e-1)" "unprognostic (1.37e-1)" "unprognostic (7.72e-13)" "unprognostic (4.54e-3)" "unprognostic (3.46e-2)" "unprognostic (1.30e-3)" "unprognostic (2.18e-2)" 1.7 0.3 0.4 0.3 2.4 52.3 2.7 53.8 26.5 3.2 7.3 1.7 0.3 0.5 0.3 1.2 0.7 0.4 0.6 2.8 11.7 2.1 1.1 1.2 2.5 11.8 0.0 1.8 1.8 0.3 1.9 0.9 3.2 2.5 0.4 0.0 3.0 0.2 0.4 4.1 2.7 0.1 5.0 1.4 1.4 1.4 5.5 2.7 0.9 0.1 0.5 0.9 2.8 11.4 2.6 0.3 0.5 5.5 0.1 0.0 6.6 0.0 0.4 1.2 0.9 0.1 1.6 1.3 0.7 0.1 0.5 1.2 0.3 0.7 0.5 1.8 1.6 0.9 0.5 0.4 0.1 0.8 1.1 0.1 0.3 0.3 0.6 0.1 0.5 1.4 4.4 7.0 0.2 0.5 8.6 7.8 2.0 0.8 0.8 4.0 1.3 10.5 0.3 0.0 4.0 0.9 3.3 0.8 1.2 0.6 1.1 2.8 0.5 2.5 3.8 1.5 2.6 12.5 15.1 6.1 12.6 2.3 1.2 257.4 43.0 106.3 66.4 42.1 76.6 73.6 52.1 61.6 49.0 119.6 39.4 37.1 60.4 70.7 39.5 48.6 56.9 31.4 0.4 2.4 53.8 26.5 2.8 11.7 11.8 0.0 3.2 5.0 5.5 11.4 3.6 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.2 0.0 0.0 0.0 0.0 8.0 18.6 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 11.3 2.5 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 7.3 1.8 0.0 0.0 0.0 H2AX H2AFX ENSG00000188486 "H2A.X variant histone" P16104 11 119093854-119095467 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair, Host-virus interaction, Meiosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 43.7;Cytotrophoblasts: 83.2;dendritic cells: 34.0;Extravillous trophoblasts: 106.6;Hofbauer cells: 45.8;Syncytiotrophoblasts: 64.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012264, HPA041189, HPA051647" Supported Supported "Nucleoplasm,Nuclear speckles" Yes Yes "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Nuclear speckles" "CAB012264: AB_297215, HPA041189: AB_2677357, HPA051647: AB_2681563" "unprognostic (1.44e-1)" "unprognostic (1.96e-1)" "unprognostic (6.46e-2)" "unprognostic (6.41e-2)" "unprognostic (3.07e-1)" "unprognostic (3.25e-1)" "prognostic unfavorable (1.51e-4)" "unprognostic (2.32e-3)" "unprognostic (1.93e-1)" "unprognostic (3.07e-3)" "unprognostic (6.78e-2)" "unprognostic (9.31e-2)" "prognostic unfavorable (5.47e-9)" "unprognostic (1.21e-3)" "unprognostic (1.20e-1)" "unprognostic (1.20e-1)" "unprognostic (1.99e-2)" 13.2 20.7 35.2 12.6 37.8 24.9 8.0 39.0 42.2 13.3 20.6 18.6 13.3 14.0 2.1 43.6 13.1 3.1 13.4 33.7 32.3 17.0 13.9 14.3 16.0 43.9 38.9 18.7 11.6 3.4 24.3 11.0 37.8 15.7 4.3 6.6 11.4 4.7 12.4 18.1 18.8 3.5 38.0 24.0 16.1 15.4 37.8 30.5 10.4 3.6 12.0 11.8 15.7 51.8 132.1 77.9 120.3 72.3 10.9 7.9 126.4 146.0 44.0 80.3 70.4 124.0 55.1 89.7 85.9 34.0 60.5 134.0 57.5 41.7 21.5 133.4 161.0 182.2 20.7 129.8 11.4 90.5 108.9 6.7 9.0 34.2 21.0 13.1 40.7 115.4 149.9 143.1 38.9 335.6 207.8 269.9 87.5 60.0 162.6 200.7 141.6 42.7 37.5 56.3 127.6 152.0 116.0 66.6 20.6 20.6 99.8 68.2 50.9 77.7 204.2 63.8 110.2 38.7 40.8 92.3 17.9 145.2 155.0 3.8 1.3 4.2 1.6 0.6 0.8 0.9 1.7 1.7 1.8 0.8 1.1 1.0 0.6 2.2 0.8 0.8 1.6 1.2 35.2 37.8 39.0 42.2 33.7 32.3 43.9 38.9 37.8 38.0 37.8 51.8 43.7 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 0.0 0.0 0.0 83.2 34.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 106.6 9.4 0.0 0.0 0.0 0.0 0.0 0.0 45.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 64.2 7.2 0.0 0.0 0.0 HAS2 ENSG00000170961 "Hyaluronan synthase 2" Q92819 8 121612116-121641440 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 22.7;urinary bladder: 20.5" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 54.1;Fibroblasts: 62.1;Langerhans cells: 28.9;Melanocytes: 30.2;Smooth muscle cells: 30.7;Urothelial cells: 89.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "HBF TERT88: 157.8;hTEC/SVTERT24-B: 153.8;LHCN-M2: 206.5;U-138 MG: 396.9;U-251 MG: 123.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA052060 Approved "Nuclear speckles" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nuclear speckles" "HPA052060: AB_2681712" "unprognostic (7.01e-2)" "unprognostic (1.34e-2)" "unprognostic (4.07e-2)" "unprognostic (4.65e-2)" "unprognostic (1.17e-1)" "unprognostic (2.91e-2)" "unprognostic (5.33e-2)" "unprognostic (2.57e-3)" "unprognostic (3.44e-2)" "unprognostic (1.34e-1)" "unprognostic (8.19e-3)" "unprognostic (1.24e-1)" "unprognostic (1.66e-7)" "unprognostic (1.47e-3)" "unprognostic (3.67e-2)" "unprognostic (1.23e-1)" "unprognostic (1.54e-3)" 22.7 0.3 0.6 9.0 0.5 0.1 5.3 0.6 0.5 0.7 0.1 4.1 2.8 0.8 1.2 1.6 1.7 7.8 4.0 0.5 1.5 1.1 2.9 3.7 1.6 1.6 2.1 0.2 0.9 0.2 0.3 2.3 1.3 1.1 5.6 0.0 1.0 0.2 0.5 2.3 5.2 3.9 1.1 0.1 2.0 1.8 1.3 0.8 0.7 0.9 0.9 20.5 0.6 0.9 0.3 2.8 0.0 0.4 4.7 11.8 0.0 23.5 17.3 29.9 51.2 0.2 0.4 0.1 0.0 20.8 0.0 4.2 0.0 0.0 157.8 0.1 0.6 0.0 0.6 0.0 19.9 0.0 0.0 31.0 0.0 153.8 14.1 0.7 0.0 0.0 0.0 0.0 206.5 0.3 0.0 0.0 0.4 0.0 3.4 0.0 26.6 0.0 0.0 2.0 0.0 0.4 10.0 0.0 5.6 9.0 0.2 0.3 0.0 396.9 1.4 37.7 123.7 0.0 0.0 0.0 8.5 0.1 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.6 0.5 0.5 1.5 1.6 2.1 1.3 1.1 1.3 0.9 2.2 0.0 0.0 0.0 0.0 16.3 54.1 1.8 0.6 0.0 0.1 0.4 1.2 0.0 0.2 3.7 0.0 0.2 0.2 1.6 0.0 0.9 19.0 0.1 3.5 7.2 1.2 0.0 0.1 0.0 0.0 62.1 1.1 0.1 13.4 0.0 0.7 0.0 0.3 0.0 0.2 2.3 0.0 0.0 28.9 3.4 1.8 0.7 30.2 0.0 0.0 0.0 0.0 16.1 0.2 1.6 1.9 0.0 0.0 11.0 0.0 0.1 0.0 0.0 0.0 6.9 30.7 0.3 0.1 0.6 11.9 0.1 1.5 0.0 3.9 89.3 HAUS6 "dgt6, FAM29A, FLJ20060, KIAA1574" ENSG00000147874 "HAUS augmin like complex subunit 6" Q7Z4H7 9 19053141-19102904 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 124.9;Spermatocytes: 68.9;Spermatogonia: 56.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 215.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020960, HPA020965" Approved Approved "Nuclear speckles,Centriolar satellite,Cytosol" No No "Cluster 38: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 36: HEL - Hemostasis" "Cluster 29: Early spermatids - Spermatogenesis" "Centriolar satellite, Cytosol" "Nuclear speckles" "HPA020960: AB_1848393, HPA020965: AB_1848394" "unprognostic (1.58e-1)" "unprognostic (9.85e-2)" "unprognostic (6.04e-3)" "unprognostic (6.51e-3)" "unprognostic (1.04e-1)" "unprognostic (1.99e-1)" "prognostic unfavorable (3.84e-4)" "unprognostic (1.21e-1)" "unprognostic (2.15e-1)" "unprognostic (1.27e-1)" "unprognostic (3.69e-2)" "unprognostic (1.48e-2)" "prognostic unfavorable (3.13e-5)" "unprognostic (2.52e-1)" "unprognostic (1.68e-1)" "unprognostic (3.13e-2)" "unprognostic (2.03e-1)" 5.3 6.5 5.2 7.9 7.3 17.0 9.2 8.9 7.4 5.4 4.2 5.8 4.0 7.1 6.2 5.2 4.7 5.1 5.2 5.1 6.2 4.1 6.9 4.7 11.4 6.4 6.2 8.2 3.9 6.1 3.0 6.9 6.6 5.6 6.2 9.1 4.5 5.6 4.4 8.1 5.2 7.2 6.1 6.9 4.3 24.0 6.1 15.1 5.3 7.2 10.7 6.2 4.2 9.3 34.7 23.7 46.4 36.3 17.4 20.9 25.1 36.5 25.5 32.7 49.9 12.2 15.4 40.5 13.1 21.1 25.0 14.2 43.3 21.3 50.4 36.8 20.9 215.8 42.1 27.8 11.6 29.0 46.7 13.0 21.5 30.9 66.9 16.9 24.0 40.4 29.8 25.7 37.8 11.3 56.6 49.1 49.9 19.4 23.2 43.3 31.8 16.4 18.0 19.8 27.1 37.3 16.4 15.0 23.6 29.5 11.6 36.1 24.1 29.3 17.7 25.5 42.2 10.2 24.0 39.7 27.3 24.0 13.0 9.8 1.5 1.6 2.8 1.5 3.9 2.3 2.8 3.6 1.5 2.3 3.3 2.9 2.3 5.0 1.4 1.8 3.7 1.7 5.2 7.3 8.9 7.4 5.1 6.2 6.4 6.2 6.6 6.1 6.1 9.3 15.9 19.2 12.5 7.8 14.3 9.7 12.6 8.7 9.1 11.8 9.4 9.3 8.4 5.7 7.2 9.2 10.4 10.5 21.9 5.6 0.0 9.8 124.9 11.8 14.4 11.6 2.4 34.1 10.3 6.1 15.3 9.5 5.6 15.3 11.4 23.8 3.9 6.8 8.2 11.8 10.2 4.6 2.0 5.8 7.7 28.2 11.8 14.5 8.8 10.3 8.2 13.5 12.3 7.1 16.8 9.0 3.4 8.2 17.3 14.6 4.5 3.2 3.6 9.7 6.6 16.2 10.1 68.9 56.0 9.1 8.1 4.9 18.2 11.0 9.4 9.4 HBP1 ENSG00000105856 "HMG-box transcription factor 1" O60381 7 107168961-107202522 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 332.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020225, CAB032824" Approved Supported "Nuclear speckles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear speckles" "CAB032824: AB_2114615, HPA020225: " "unprognostic (9.00e-2)" "unprognostic (1.70e-1)" "unprognostic (1.06e-1)" "unprognostic (4.43e-1)" "unprognostic (4.79e-2)" "unprognostic (7.49e-3)" "unprognostic (1.99e-1)" "unprognostic (2.25e-2)" "unprognostic (3.47e-2)" "unprognostic (2.07e-2)" "unprognostic (2.99e-3)" "unprognostic (1.50e-1)" "prognostic favorable (7.70e-5)" "unprognostic (7.39e-2)" "unprognostic (2.31e-1)" "unprognostic (7.69e-2)" "unprognostic (5.26e-2)" 58.4 49.8 13.2 15.0 18.3 49.0 52.4 17.1 14.8 50.1 15.2 45.9 16.3 53.1 20.0 54.4 40.0 19.9 39.8 13.0 14.7 26.7 37.8 40.1 17.3 19.2 16.1 51.1 34.9 29.0 24.2 24.6 19.2 35.4 17.8 16.5 46.6 22.5 86.4 70.9 34.9 22.1 15.0 34.0 38.0 57.1 14.9 23.6 36.8 39.6 19.9 43.4 51.5 25.7 9.0 10.1 18.8 12.2 38.7 36.1 8.8 15.6 35.1 11.2 19.6 3.6 23.5 8.7 20.4 21.8 23.3 11.4 7.7 9.7 13.9 6.5 7.0 6.0 16.7 6.9 22.1 4.3 17.3 42.3 28.3 10.9 13.3 37.7 37.0 8.8 11.3 21.2 14.5 14.8 7.3 13.6 11.8 12.8 11.5 6.9 13.8 22.4 19.9 11.1 7.3 22.0 18.4 26.7 25.9 25.9 8.3 13.2 35.8 14.7 11.4 22.7 4.7 24.6 31.9 9.0 14.4 9.2 15.3 142.1 59.5 80.0 37.5 61.7 35.8 35.6 39.5 36.5 40.3 34.6 45.2 38.5 146.2 53.8 64.1 20.5 55.6 91.8 13.2 18.3 17.1 14.8 13.0 14.7 19.2 16.1 19.2 15.0 14.9 25.7 67.9 22.4 39.7 37.2 72.9 108.2 77.6 56.2 91.6 29.7 83.1 54.7 22.1 31.5 51.6 33.1 8.4 46.1 95.5 56.1 45.0 50.5 175.9 56.8 45.8 51.8 54.2 59.5 32.6 32.3 26.1 76.8 50.4 93.3 50.7 25.7 35.3 36.8 28.9 42.1 35.2 41.3 85.5 49.8 81.8 332.7 54.0 67.8 74.7 49.6 46.3 33.4 37.0 40.2 91.4 33.7 46.6 57.9 70.2 82.8 55.1 45.3 37.6 29.2 46.0 91.4 70.0 53.0 38.0 55.3 133.0 210.4 94.8 42.6 28.1 89.9 HDAC4 "BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACA, KIAA0288" ENSG00000068024 "Histone deacetylase 4" P56524 2 239048168-239401654 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "Autism spectrum disorder, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 58.2" "Group enriched" "Detected in many" 4 "Astrocytes: 62.0;Early spermatids: 69.9;Excitatory neurons: 118.1;Inhibitory neurons: 84.9;Late spermatids: 59.0;Microglial cells: 38.4;Oligodendrocyte precursor cells: 85.5;Oligodendrocytes: 124.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 32.0;neutrophil: 47.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 47.7" "Cell line enhanced" "Detected in many" "JURKAT: 49.1;MOLT-4: 48.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048723, HPA071448" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear speckles" "Nucleoplasm, Cytosol" "HPA048723: AB_2680501, HPA071448: " "unprognostic (1.54e-1)" "unprognostic (1.76e-2)" "unprognostic (1.33e-1)" "unprognostic (1.18e-3)" "unprognostic (2.43e-2)" "unprognostic (2.39e-3)" "unprognostic (3.06e-4)" "unprognostic (1.00e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (6.33e-4)" "prognostic favorable (1.13e-4)" "unprognostic (1.40e-1)" "unprognostic (4.82e-3)" "unprognostic (2.40e-1)" "unprognostic (3.26e-2)" "unprognostic (1.32e-2)" "unprognostic (6.04e-2)" 4.4 6.3 9.3 5.0 12.0 17.0 3.8 0.6 13.4 7.5 0.1 29.0 2.7 9.1 2.5 8.0 6.7 7.1 5.2 9.0 6.5 3.7 2.4 3.9 3.5 9.9 6.1 7.5 3.7 2.7 6.5 1.5 11.2 5.6 3.4 2.4 3.3 5.9 58.2 5.9 7.2 6.2 2.3 5.6 7.2 9.2 6.7 9.7 4.2 35.6 2.5 10.0 4.5 10.1 3.2 5.8 4.1 6.1 4.5 3.9 5.9 3.0 2.3 2.3 1.7 2.9 7.5 2.0 1.9 3.4 3.6 3.4 4.0 2.0 1.4 12.8 1.8 3.1 5.1 5.8 3.8 5.5 4.6 4.4 2.6 4.6 3.3 2.3 2.4 49.1 3.7 4.5 2.7 4.7 48.1 10.7 4.0 6.0 2.8 7.6 7.2 4.0 5.3 4.4 4.6 6.4 5.3 2.5 16.2 2.6 1.0 17.9 1.9 5.0 0.4 6.8 4.6 3.3 3.2 3.1 6.9 6.9 7.4 32.0 10.2 2.3 1.0 3.3 1.2 0.2 1.1 1.0 1.0 0.1 0.5 0.5 47.7 3.2 1.7 0.6 1.7 1.1 9.3 12.0 0.6 13.4 9.0 6.5 9.9 6.1 11.2 2.3 6.7 10.1 8.6 3.2 7.4 62.0 5.2 7.9 2.9 3.0 8.6 12.2 6.2 4.8 13.3 7.2 2.9 11.0 2.1 1.5 12.8 4.1 0.0 2.8 69.9 7.0 15.1 7.1 6.0 6.1 118.1 2.2 1.7 14.0 7.7 7.4 2.5 6.6 11.7 6.7 3.2 16.8 84.9 5.2 2.0 17.2 10.0 59.0 11.8 10.3 5.4 38.4 14.9 8.6 15.5 85.5 124.0 1.9 1.6 12.4 7.0 6.4 5.0 1.6 2.6 7.1 0.0 18.7 6.5 2.8 3.3 11.1 9.7 1.4 12.2 4.9 6.4 2.7 HDAC5 "FLJ90614, KIAA0600, NY-CO-9" ENSG00000108840 "Histone deacetylase 5" Q9UQL6 17 44076746-44123702 "Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 118.9;Syncytiotrophoblasts: 218.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019400, HPA030991" Approved Supported "Nuclear speckles,Golgi apparatus,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nuclear speckles" "Golgi apparatus, Cytosol" "CAB019400: AB_2116626, HPA030991: AB_10795286" "unprognostic (1.30e-2)" "prognostic favorable (6.14e-4)" "unprognostic (6.65e-2)" "unprognostic (8.06e-2)" "unprognostic (3.49e-1)" "unprognostic (3.52e-2)" "prognostic unfavorable (3.12e-5)" "unprognostic (8.80e-3)" "unprognostic (3.80e-2)" "unprognostic (2.37e-2)" "unprognostic (4.91e-3)" "unprognostic (4.30e-1)" "prognostic favorable (3.30e-5)" "unprognostic (1.51e-2)" "unprognostic (3.11e-1)" "unprognostic (6.00e-2)" "unprognostic (1.76e-2)" 30.8 24.7 39.3 10.9 33.5 20.7 28.8 48.8 48.5 40.6 3.3 36.3 11.6 33.2 15.5 45.1 34.1 15.9 53.5 40.4 31.6 24.8 17.4 33.6 14.0 37.6 41.1 45.0 22.5 31.5 48.1 22.6 35.1 29.2 7.3 24.3 22.9 15.1 77.5 71.3 22.9 14.8 22.4 26.4 24.0 19.7 40.0 10.4 30.8 28.6 11.6 29.2 37.0 50.3 8.7 5.5 14.9 3.5 28.2 21.7 53.6 22.8 56.1 11.3 18.1 12.3 9.1 13.5 9.0 54.4 16.5 6.9 17.6 9.8 4.7 21.2 28.7 26.3 18.6 28.6 12.2 8.7 35.7 31.2 16.5 12.8 15.8 19.0 9.3 10.6 20.0 26.5 65.5 6.7 14.3 26.2 16.4 6.7 13.0 54.7 41.6 35.4 1.2 3.8 38.6 20.3 6.7 27.6 31.2 21.8 39.3 49.6 5.1 27.8 17.5 6.6 11.7 43.6 39.7 16.2 16.0 10.7 13.4 11.6 9.2 9.7 5.4 13.5 3.8 7.2 4.3 5.4 11.1 7.5 4.5 4.0 20.9 4.5 16.8 9.7 4.1 7.3 39.3 33.5 48.8 48.5 40.4 31.6 37.6 41.1 35.1 22.4 40.0 50.3 24.0 12.8 13.7 11.1 20.4 29.2 32.3 9.0 26.2 87.8 23.8 21.3 27.1 30.0 11.9 20.2 118.9 21.9 19.6 22.4 21.5 17.2 20.2 17.1 10.7 22.1 46.0 9.3 18.9 8.7 53.1 24.1 10.2 25.1 12.6 47.0 24.3 9.3 22.7 82.4 31.0 14.9 6.1 18.5 17.8 10.0 48.4 29.8 14.2 12.2 16.5 18.9 11.3 14.1 26.2 11.5 16.5 43.6 14.2 41.2 21.5 7.3 12.4 60.4 65.7 31.8 40.1 4.2 32.7 28.1 32.8 218.1 17.0 29.9 11.3 25.3 HEATR5B "DKFZp686P15184, KIAA1414" ENSG00000008869 "HEAT repeat containing 5B" Q9P2D3 2 36968383-37084372 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 62.3;Inhibitory neurons: 58.9;Oligodendrocyte precursor cells: 57.3;Oligodendrocytes: 69.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042025, HPA055639" Approved Approved "Nuclear speckles,Vesicles,Cytosol" NA NA 6800 "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "Nuclear speckles, Vesicles, Cytosol" "HPA042025: AB_10959880, HPA055639: AB_2682870" "unprognostic (3.11e-2)" "unprognostic (1.65e-2)" "unprognostic (4.07e-1)" "unprognostic (6.05e-2)" "unprognostic (3.70e-2)" "unprognostic (7.75e-2)" "unprognostic (5.95e-2)" "unprognostic (3.33e-3)" "unprognostic (8.26e-2)" "unprognostic (3.08e-2)" "unprognostic (1.66e-1)" "unprognostic (8.07e-2)" "unprognostic (5.80e-3)" "unprognostic (8.69e-2)" "unprognostic (4.18e-1)" "unprognostic (2.72e-1)" "unprognostic (3.95e-1)" 9.7 8.8 7.1 15.0 7.1 24.3 14.5 11.7 9.8 9.9 4.9 9.9 10.8 9.5 16.9 11.7 8.1 10.7 9.7 7.4 6.4 9.3 9.3 10.8 31.9 5.8 5.2 9.8 18.2 13.4 6.3 10.2 6.4 11.4 13.5 24.3 14.3 7.7 4.9 18.2 11.5 8.3 3.9 19.0 12.3 9.6 7.0 24.7 11.8 9.4 31.2 10.1 8.5 8.1 16.2 8.1 11.7 17.8 11.9 11.7 14.9 10.1 7.4 9.0 9.1 9.6 10.9 34.6 7.1 8.6 11.9 13.4 11.6 8.2 11.7 17.0 12.6 22.6 11.3 13.1 7.4 24.5 28.5 10.8 11.2 13.0 12.3 9.9 15.5 18.3 21.6 29.8 10.9 9.6 21.5 17.4 7.7 16.7 5.6 20.5 11.9 26.3 10.5 13.8 14.3 12.6 10.6 16.7 7.8 11.7 12.0 7.9 17.2 13.5 7.7 9.9 7.9 18.5 16.2 39.0 11.0 14.3 9.0 18.3 5.0 12.3 7.7 2.8 7.1 9.7 8.5 8.7 9.0 14.0 8.7 7.6 5.2 7.5 4.4 11.2 9.7 5.9 7.1 7.1 11.7 9.8 7.4 6.4 5.8 5.2 6.4 3.9 7.0 8.1 12.9 22.4 10.3 35.9 20.8 9.8 4.2 4.7 6.8 13.0 11.9 8.3 20.8 8.6 7.1 5.5 10.4 7.0 24.4 11.3 1.9 4.6 6.3 14.8 10.0 9.5 5.4 18.7 62.3 6.2 6.2 9.4 25.5 11.1 7.0 9.8 11.7 7.8 6.3 16.8 58.9 8.9 6.1 17.0 15.7 2.6 9.0 13.2 7.2 56.2 9.2 6.5 16.5 57.3 69.7 8.8 6.3 6.4 17.6 5.5 12.7 5.4 12.8 16.2 19.7 6.5 10.6 3.6 11.2 11.7 11.6 5.6 14.5 7.7 8.7 4.9 HELQ Hel308 ENSG00000163312 "Helicase, POLQ like" Q8TDG4 4 83407343-83455855 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036852, HPA036853" Approved Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 59: Non-specific - Transcription" "Nuclear speckles" Nucleoplasm "HPA036852: AB_2675349, HPA036853: AB_10672102" "unprognostic (4.58e-2)" "unprognostic (3.25e-2)" "unprognostic (1.12e-2)" "unprognostic (1.12e-1)" "unprognostic (4.80e-2)" "unprognostic (5.56e-2)" "unprognostic (1.14e-1)" "unprognostic (5.13e-3)" "unprognostic (7.14e-2)" "unprognostic (8.62e-2)" "prognostic favorable (9.07e-4)" "unprognostic (2.03e-1)" "prognostic favorable (2.76e-4)" "unprognostic (3.54e-2)" "unprognostic (1.43e-1)" "unprognostic (1.57e-1)" "unprognostic (1.37e-1)" 4.8 9.1 2.2 5.0 2.6 4.6 5.5 4.0 2.8 5.4 4.6 4.0 3.1 4.9 4.5 3.4 4.6 3.8 5.1 2.1 2.4 5.4 5.5 4.0 9.3 2.2 2.3 8.1 3.7 5.6 4.4 3.2 2.5 3.9 3.9 5.5 4.6 4.0 7.2 3.9 4.5 4.3 2.4 6.2 3.7 6.0 2.4 8.0 5.8 8.1 7.5 4.4 4.0 3.0 4.0 2.9 6.0 4.0 7.5 7.2 3.1 5.5 7.9 7.2 6.9 2.9 4.1 11.2 4.3 5.1 4.9 4.0 6.9 3.9 7.7 6.5 3.3 6.3 4.8 3.9 4.5 8.4 15.9 6.1 5.5 5.9 5.8 6.1 5.3 7.2 8.8 9.4 7.0 4.3 7.5 5.9 2.7 6.0 2.2 5.9 7.1 3.9 6.2 2.3 4.7 4.2 5.6 6.2 6.6 5.9 3.8 8.3 4.6 5.4 4.8 6.7 4.4 8.7 3.8 9.2 4.7 6.1 6.1 3.4 1.7 3.6 3.1 2.2 3.2 3.4 3.3 3.2 2.6 5.1 5.6 4.7 1.3 3.6 3.1 2.5 4.5 1.6 2.2 2.6 4.0 2.8 2.1 2.4 2.2 2.3 2.5 2.4 2.4 3.0 14.1 3.2 14.0 14.4 23.1 4.2 8.6 6.6 12.0 10.2 6.7 9.0 12.3 5.7 7.7 5.5 8.4 10.9 11.4 4.5 11.7 6.7 28.3 7.3 10.2 10.2 0.0 7.8 17.0 5.4 10.3 11.1 4.1 7.7 7.6 9.8 10.0 4.1 10.2 6.7 21.3 5.5 4.1 7.2 5.4 8.9 13.1 9.9 7.2 20.6 10.7 7.8 17.5 10.6 15.7 4.4 8.3 7.9 15.8 5.4 7.6 11.8 15.9 13.8 0.0 11.2 11.9 24.3 12.7 7.0 3.8 11.5 18.2 17.4 5.5 6.1 HES5 bHLHb38 ENSG00000197921 "Hes family bHLH transcription factor 5" Q5TA89 1 2528745-2530263 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 18.7;skin 1: 4.8" "Cell type enhanced" "Detected in some" "Adipocytes: 24.8;Astrocytes: 53.5;Muller glia cells: 113.4;Oligodendrocyte precursor cells: 15.6" "Cancer enriched" "Detected in some" 5 "glioma: 3.8" "Group enriched" "Detected in many" 4 "amygdala: 10.3;basal ganglia: 14.2;cerebral cortex: 5.1;hypothalamus: 12.4;thalamus: 18.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA065458, HPA076164" Enhanced Approved "Nucleoplasm,Nuclear speckles,Cytosol" No NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "Nuclear speckles, Cytosol" "HPA065458: AB_2685492, HPA076164: AB_2732303" "unprognostic (2.04e-3)" "unprognostic (2.83e-2)" "unprognostic (4.26e-2)" "unprognostic (2.75e-3)" "unprognostic (5.26e-3)" "unprognostic (1.60e-4)" "unprognostic (1.76e-4)" "unprognostic (1.60e-1)" "unprognostic (5.30e-2)" "unprognostic (9.51e-2)" "unprognostic (1.16e-1)" "unprognostic (4.67e-1)" "unprognostic (9.95e-4)" "unprognostic (1.14e-3)" "unprognostic (1.45e-1)" "unprognostic (3.89e-2)" "unprognostic (1.72e-1)" 0.5 0.0 10.3 0.0 14.2 0.0 0.3 0.7 5.1 0.4 0.0 0.5 0.0 0.2 0.0 0.8 0.2 0.0 2.5 2.8 12.4 0.1 0.3 0.3 0.0 1.1 0.9 0.1 0.0 0.0 2.5 0.0 1.0 0.4 0.0 0.0 0.1 0.0 0.1 4.8 0.2 0.0 0.4 0.2 0.1 0.9 18.7 0.0 0.5 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 14.2 0.7 5.1 2.8 12.4 1.1 0.9 1.0 0.4 18.7 0.0 24.8 0.0 0.0 53.5 0.2 0.1 0.3 0.2 1.8 2.9 1.1 2.8 1.4 0.0 0.3 0.0 0.0 0.0 0.4 4.0 0.0 0.0 0.0 5.4 0.8 5.1 0.0 0.0 0.7 0.0 0.0 0.3 0.0 8.9 0.0 0.1 0.0 0.0 0.0 3.3 0.8 4.9 0.0 0.0 0.8 0.0 0.0 0.3 0.0 1.9 0.0 113.4 0.0 15.6 0.3 0.0 2.9 0.0 0.0 0.5 0.1 0.0 0.0 7.7 0.0 1.0 6.2 0.0 0.4 6.2 1.4 0.0 0.5 0.0 3.0 0.2 HEXIM2 FLJ32384 ENSG00000168517 "HEXIM P-TEFb complex subunit 2" Q96MH2 17 45160700-45170040 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 56.9;testis: 44.6" "Group enriched" "Detected in many" 5 "Early spermatids: 150.9;Late spermatids: 274.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 55.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023323, HPA028455" Enhanced Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 37: B-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Nuclear speckles" "HPA023323: AB_1850651, HPA028455: AB_10602603" "unprognostic (9.03e-3)" "unprognostic (2.18e-2)" "unprognostic (4.01e-2)" "prognostic favorable (2.53e-4)" "unprognostic (2.36e-1)" "unprognostic (6.35e-3)" "unprognostic (9.70e-2)" "unprognostic (1.34e-2)" "unprognostic (1.03e-1)" "prognostic favorable (9.85e-4)" "unprognostic (2.34e-3)" "unprognostic (1.93e-1)" "unprognostic (1.29e-2)" "unprognostic (2.32e-3)" "unprognostic (6.98e-2)" "unprognostic (2.04e-1)" "unprognostic (1.90e-2)" 4.8 10.1 8.5 5.2 9.0 4.6 4.6 12.2 9.8 4.9 13.4 7.1 10.2 4.7 4.5 4.7 5.6 7.8 6.9 7.2 7.3 10.5 15.1 4.2 7.3 9.1 8.4 6.2 10.8 7.5 7.9 3.4 8.2 6.0 2.7 4.8 11.5 5.7 56.9 6.6 7.6 2.8 8.6 6.4 8.1 44.6 9.0 5.0 8.7 15.1 3.3 5.8 3.9 9.1 9.0 31.7 6.9 15.3 7.5 12.3 13.1 4.9 5.9 7.8 8.6 12.1 23.4 5.6 25.0 3.5 4.0 14.6 6.8 6.0 2.4 12.9 10.9 4.2 33.4 55.1 5.4 3.6 8.9 10.7 5.6 6.8 2.4 15.1 3.9 11.3 4.6 13.4 3.6 15.6 5.7 7.6 7.5 12.5 13.8 7.7 10.4 17.1 9.8 8.8 8.2 7.2 4.4 8.8 20.7 4.8 23.3 6.1 3.8 14.0 7.5 9.4 11.7 20.7 23.9 5.2 11.0 6.6 10.7 8.2 11.7 10.6 4.8 9.4 8.0 10.1 3.5 5.8 10.2 5.5 2.7 5.0 8.2 8.1 3.1 12.9 4.7 12.0 8.5 9.0 12.2 9.8 7.2 7.3 9.1 8.4 8.2 8.6 9.0 9.1 3.1 0.0 1.5 1.6 4.8 2.0 4.0 3.1 5.7 13.1 6.8 7.2 0.3 5.7 2.5 1.8 4.2 11.7 4.1 2.7 19.6 5.5 150.9 4.9 3.0 4.3 4.8 0.8 2.2 1.6 5.4 3.9 3.6 3.4 7.0 8.8 5.3 7.7 7.0 3.3 3.0 6.2 4.1 9.3 3.3 274.9 5.9 16.4 3.6 1.0 4.9 11.6 5.2 1.5 3.1 1.6 3.1 7.2 7.2 2.0 18.3 36.2 1.8 9.9 0.0 5.4 4.6 41.4 13.7 3.3 3.0 6.2 2.1 7.2 6.1 2.5 HIKESHI "C11orf73, HSPC138, HSPC179, OPI10" ENSG00000149196 "Heat shock protein nuclear import factor hikeshi" Q53FT3 11 86302211-86345943 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 129.6;Extravillous trophoblasts: 146.2;Hofbauer cells: 94.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012708, HPA035063, HPA035064" Approved Approved "Nucleoplasm,Nuclear speckles,Nuclear bodies" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 7: Non-specific - Mitochondria" "Nuclear speckles" "Nucleoplasm, Nuclear bodies" "HPA012708: , HPA035063: AB_10601143, HPA035064: AB_2674441" "unprognostic (1.10e-3)" "unprognostic (5.09e-2)" "unprognostic (1.92e-1)" "unprognostic (2.40e-2)" "unprognostic (1.50e-1)" "unprognostic (2.18e-1)" "prognostic unfavorable (8.81e-4)" "unprognostic (9.92e-2)" "unprognostic (1.16e-1)" "unprognostic (2.67e-2)" "unprognostic (8.24e-2)" "unprognostic (3.19e-2)" "prognostic unfavorable (4.01e-12)" "unprognostic (1.76e-1)" "unprognostic (2.58e-1)" "unprognostic (1.33e-3)" "unprognostic (1.71e-1)" 34.7 27.0 46.1 17.8 46.7 19.0 31.4 47.8 71.5 33.9 44.5 40.8 10.4 32.3 24.7 33.4 31.0 15.0 57.1 46.1 47.2 17.0 24.7 23.9 26.0 46.6 46.0 37.5 22.8 22.9 31.5 28.3 47.1 24.5 19.1 32.5 19.8 28.6 59.9 29.5 20.8 31.1 49.1 28.5 23.5 19.0 47.1 32.9 17.7 57.8 30.8 32.8 31.8 50.9 28.6 30.5 72.7 40.5 59.9 74.2 38.2 43.2 52.0 44.2 52.6 90.8 77.8 29.0 96.9 57.4 83.9 59.9 54.2 95.1 47.0 62.0 47.6 47.0 47.5 68.2 80.8 58.0 36.8 52.7 94.9 52.8 62.5 56.9 85.9 54.7 51.1 64.6 91.5 78.0 69.6 136.7 59.5 186.3 20.1 53.0 35.7 65.4 77.2 53.2 44.8 38.7 53.8 39.8 31.1 72.7 64.1 38.5 44.2 52.1 36.4 105.8 32.7 27.7 68.3 57.6 26.6 54.4 52.6 47.8 53.4 44.4 48.6 52.5 54.3 61.8 59.1 53.6 68.9 52.9 51.1 52.3 11.2 57.9 53.9 53.7 84.5 43.2 46.1 46.7 47.8 71.5 46.1 47.2 46.6 46.0 47.1 49.1 47.1 50.9 59.9 38.5 32.1 0.0 16.1 0.0 0.0 0.0 0.0 0.0 53.4 81.3 0.0 0.0 14.9 27.6 0.0 129.6 28.7 0.0 41.1 76.1 0.0 41.4 60.4 28.7 0.0 0.0 0.0 66.3 146.2 30.2 0.0 36.8 22.7 52.1 0.0 0.0 94.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.6 0.0 0.0 50.1 0.0 0.0 0.0 0.0 49.8 0.0 0.0 4.1 0.0 0.0 43.2 27.7 0.0 0.0 0.0 34.7 0.0 0.0 0.0 0.0 77.6 18.1 59.3 0.0 0.0 HOXA6 "HOX1, HOX1B" ENSG00000106006 "Homeobox A6" P31267 7 27145396-27150603 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 10.0" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 5.2;Distal enterocytes: 7.5;Distal tubular cells: 5.9;Endometrial stromal cells: 14.8;Enteroendocrine cells: 9.0;Smooth muscle cells: 6.2;Undifferentiated cells: 8.0" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 7.7" "Immune cell enhanced" "Detected in single" "basophil: 3.1" "Lineage enhanced" "Detected in single" "granulocytes: 3.1" "Group enriched" "Detected in many" 9 "AN3-CA: 61.7;HEK 293: 84.4" "Region enriched" "Detected in single" 34 "pons and medulla: 3.3" "HPA004203, HPA077900" Approved Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 36: Stromal cells - Cell proliferation" Nucleoplasm "Nuclear speckles" "HPA004203: AB_1079079, HPA077900: " "unprognostic (1.70e-1)" "unprognostic (6.76e-3)" "unprognostic (2.70e-2)" "prognostic unfavorable (1.40e-4)" "unprognostic (1.06e-1)" "unprognostic (6.06e-2)" "unprognostic (9.73e-2)" "unprognostic (6.32e-2)" "unprognostic (2.94e-2)" "unprognostic (7.82e-2)" "unprognostic (2.17e-1)" "prognostic favorable (2.03e-4)" "unprognostic (1.45e-1)" "unprognostic (2.81e-2)" "unprognostic (3.93e-1)" 3.0 2.7 0.1 1.4 0.1 0.2 2.4 0.0 0.2 2.5 0.0 6.6 0.2 5.4 3.7 0.3 10.0 0.2 0.0 0.1 0.0 4.5 0.0 2.1 1.1 7.1 0.0 0.2 0.0 0.3 0.0 0.1 1.8 2.5 1.5 0.0 0.1 1.9 1.2 2.9 4.2 1.4 7.7 0.2 1.3 0.0 0.0 0.1 0.2 0.0 0.0 3.0 1.4 5.4 1.2 2.1 0.1 61.7 0.1 0.0 0.2 0.5 0.6 0.4 0.6 1.5 7.2 1.5 2.3 0.5 0.2 2.8 1.5 0.0 0.0 1.9 84.4 1.0 1.2 0.8 0.0 1.3 2.1 4.9 0.1 0.0 0.8 0.1 2.9 2.0 0.4 0.0 0.7 0.8 0.1 0.3 0.1 0.4 2.1 8.4 0.0 0.0 5.9 3.9 6.4 0.0 2.9 0.3 1.3 0.0 0.8 0.8 0.0 0.1 0.9 3.3 2.3 0.0 0.0 1.4 0.0 6.2 6.1 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 7.1 0.0 1.8 7.7 0.0 5.4 2.1 0.0 0.0 0.0 0.3 0.3 1.6 0.0 0.0 0.0 4.0 5.2 0.0 0.0 0.0 1.8 0.0 0.0 0.5 7.5 5.9 0.0 0.0 0.6 14.8 1.9 9.0 0.0 0.0 0.0 0.0 1.8 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.7 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 3.9 0.0 0.0 1.0 3.4 1.3 0.1 0.0 0.0 3.7 6.2 0.0 0.0 0.3 0.4 0.0 0.4 0.1 8.0 1.4 HP1BP3 HP1-BP74 ENSG00000127483 "Heterochromatin protein 1 binding protein 3" Q5SSJ5 1 20740266-20787323 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028215, HPA054295" Supported Supported "Nuclear speckles" NA Yes 30000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nuclear speckles" "HPA028215: AB_10601021, HPA054295: AB_2682440" "unprognostic (3.90e-3)" "unprognostic (6.83e-2)" "unprognostic (7.69e-2)" "unprognostic (3.66e-2)" "unprognostic (1.31e-1)" "unprognostic (1.25e-3)" "prognostic unfavorable (2.76e-4)" "unprognostic (1.97e-1)" "unprognostic (3.26e-2)" "unprognostic (1.68e-1)" "unprognostic (1.94e-2)" "unprognostic (9.50e-2)" "unprognostic (6.86e-2)" "unprognostic (1.65e-1)" "unprognostic (6.30e-2)" "unprognostic (1.27e-1)" "unprognostic (2.43e-2)" 87.9 78.9 62.2 76.2 75.1 141.7 80.1 69.6 76.5 143.6 62.1 107.9 71.3 116.5 63.0 94.8 96.7 75.3 75.7 64.5 66.6 83.5 66.5 84.1 91.4 68.1 64.4 135.6 74.4 98.1 60.9 85.9 67.5 81.3 88.2 96.4 83.0 74.3 113.9 86.9 93.8 100.3 61.3 89.2 83.1 54.5 68.7 134.5 106.3 78.7 90.3 93.9 114.2 107.6 207.3 106.1 261.6 157.5 152.3 172.8 157.3 230.2 182.4 156.7 163.1 97.6 232.0 208.2 113.4 176.6 108.4 171.9 136.7 125.5 199.8 306.5 124.7 296.2 230.5 85.4 98.1 209.7 181.7 135.1 90.6 159.0 208.5 193.0 160.5 245.1 169.9 251.8 180.1 64.2 323.5 93.0 69.3 152.6 126.3 250.4 255.0 219.2 113.6 66.6 175.0 180.0 279.8 112.9 181.2 132.9 117.3 138.7 196.4 176.2 164.2 180.7 139.2 144.0 194.2 246.7 150.2 213.0 204.0 102.4 55.3 202.6 57.1 45.0 59.7 70.8 61.9 62.1 52.2 58.4 80.4 54.5 66.1 63.3 54.9 59.5 71.6 49.0 62.2 75.1 69.6 76.5 64.5 66.6 68.1 64.4 67.5 61.3 68.7 107.6 129.4 150.6 156.2 96.9 112.1 130.4 137.4 81.6 159.9 117.8 116.6 108.7 161.4 94.4 94.5 104.8 54.2 87.6 144.7 105.6 154.6 87.0 40.8 85.3 184.6 136.8 103.7 214.6 98.3 93.4 70.7 161.9 98.8 128.2 137.8 131.8 129.2 101.0 72.6 80.8 93.7 113.4 83.4 100.7 104.1 22.3 172.7 116.9 113.8 130.2 111.2 119.5 127.7 142.7 189.9 113.0 90.1 162.5 162.0 124.6 91.7 110.7 54.6 97.6 157.8 145.2 148.3 141.3 110.1 201.8 134.5 92.9 151.9 116.2 115.3 118.4 HPD "4-HPPD, 4HPPD, GLOD3, PPD" ENSG00000158104 "4-hydroxyphenylpyruvate dioxygenase" P32754 12 121839527-121863596 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" "Dioxygenase, Oxidoreductase" "Disease variant, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 2530.4" "Group enriched" "Detected in some" 9 "Hepatocytes: 1373.6;Proximal tubular cells: 2144.0" "Cancer enriched" "Detected in many" 100 "liver cancer: 540.9" "Region enhanced" "Detected in many" "hippocampal formation: 7.8" "Immune cell enhanced" "Detected in some" "eosinophil: 7.8" "Group enriched" "Detected in many" 4 "dendritic cells: 3.8;granulocytes: 7.8" "Cell line enriched" "Detected in some" 31 "Hep G2: 516.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038321, HPA038322" Enhanced Uncertain "Nuclear speckles" NA NA 26000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles" "HPA038321: AB_2675957, HPA038322: AB_10670778" "unprognostic (3.01e-2)" "unprognostic (2.30e-1)" "unprognostic (4.81e-3)" "unprognostic (1.42e-3)" "unprognostic (1.10e-2)" "unprognostic (9.08e-2)" "unprognostic (1.13e-2)" "unprognostic (8.84e-2)" "unprognostic (5.58e-2)" "unprognostic (6.14e-3)" "unprognostic (9.72e-3)" "unprognostic (8.61e-3)" "unprognostic (7.16e-2)" "unprognostic (1.97e-1)" "unprognostic (4.12e-1)" "unprognostic (3.06e-2)" "unprognostic (2.34e-1)" 2.3 5.3 0.6 0.7 0.4 0.9 4.6 3.2 0.6 2.0 119.0 1.2 0.1 4.1 0.7 0.7 6.4 1.1 3.5 7.8 0.5 531.0 2530.4 2.0 0.3 1.5 1.0 4.7 3.9 0.1 1.1 0.3 0.8 2.3 0.5 0.3 0.2 7.3 2.2 0.2 0.9 1.4 0.6 2.3 1.9 10.2 3.5 0.1 0.7 0.1 0.1 3.7 1.9 1.0 0.3 0.9 0.6 0.6 0.3 0.6 0.6 0.0 0.1 0.0 0.0 0.2 0.5 0.2 0.6 1.1 0.2 0.4 0.2 0.0 0.0 0.3 0.8 1.2 5.4 516.4 11.5 1.8 16.4 3.6 0.3 0.0 0.0 1.3 0.0 0.5 0.8 0.0 1.3 1.3 0.2 0.4 9.9 0.4 0.0 0.3 1.6 0.5 0.0 1.4 0.1 0.1 1.5 0.1 0.1 6.9 1.1 0.9 0.2 0.0 0.3 0.1 0.1 0.8 0.6 0.7 0.2 1.2 0.0 0.0 0.6 7.8 0.0 0.8 0.0 0.1 0.1 0.1 1.0 0.1 0.2 0.2 3.9 0.0 1.3 3.8 0.0 0.3 0.6 0.4 3.2 0.6 7.8 0.5 1.5 1.0 0.8 0.6 3.5 1.0 0.0 0.0 0.0 0.7 15.8 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.3 55.8 0.0 92.0 0.0 0.8 0.0 0.0 193.7 0.5 38.0 0.1 0.0 2.6 0.0 80.2 1.0 16.2 0.3 0.4 0.0 0.1 0.0 0.0 38.9 1373.6 0.3 0.0 1.0 0.0 0.0 37.8 0.3 121.0 2.5 10.8 0.0 0.0 0.4 0.0 0.0 1.5 0.7 0.2 0.0 5.3 0.0 0.0 0.0 2144.0 0.0 0.0 0.0 2.0 0.2 1.8 1.4 0.0 0.0 1.1 8.0 7.1 0.0 0.0 HSF4 CTM ENSG00000102878 "Heat shock transcription factor 4" Q9ULV5 16 67164681-67169945 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Stress response, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 69.2" "Cell type enhanced" "Detected in many" "Astrocytes: 38.5;Excitatory neurons: 30.9;Horizontal cells: 43.7;Inhibitory neurons: 30.0;Leydig cells: 32.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 17.1;T-47d: 12.9;U-266/70: 22.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048584 Supported "Nuclear speckles" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 62: Horizontal cells - Visual perception" "Nuclear speckles" "HPA048584: AB_2680452" "unprognostic (1.90e-1)" "unprognostic (3.05e-2)" "prognostic unfavorable (8.24e-5)" "unprognostic (9.20e-3)" "unprognostic (2.61e-1)" "unprognostic (1.43e-1)" "unprognostic (8.98e-2)" "unprognostic (1.36e-1)" "unprognostic (4.06e-2)" "unprognostic (2.45e-1)" "unprognostic (2.85e-2)" "unprognostic (4.26e-3)" "prognostic unfavorable (2.19e-6)" "unprognostic (1.20e-1)" "unprognostic (1.33e-1)" "unprognostic (4.48e-2)" "unprognostic (8.74e-3)" 12.4 23.7 43.6 1.3 44.3 1.8 12.7 44.6 69.2 17.9 39.2 10.1 4.8 12.4 4.8 11.0 21.1 3.6 20.0 44.6 43.7 17.1 20.3 8.7 1.6 45.0 41.9 19.8 35.9 4.3 30.1 3.3 46.4 28.3 1.8 5.6 19.0 1.9 25.9 14.5 6.1 2.1 41.3 6.0 14.4 7.0 43.3 1.1 17.9 4.1 1.1 18.8 10.9 45.8 1.6 1.1 0.0 1.1 0.5 3.0 5.2 0.5 0.6 0.2 0.0 2.4 3.5 0.1 2.5 1.1 0.7 5.9 0.4 0.7 0.2 2.3 2.2 0.6 4.5 3.1 2.3 0.3 4.4 1.3 4.8 0.2 2.5 17.1 0.9 4.0 1.5 5.1 2.3 1.5 0.8 1.8 0.1 3.4 3.2 2.0 1.7 8.7 4.4 2.5 3.5 7.6 4.9 3.0 7.8 2.1 12.9 4.5 0.9 1.6 1.6 6.4 1.5 22.3 3.7 1.5 4.9 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.6 44.3 44.6 69.2 44.6 43.7 45.0 41.9 46.4 41.3 43.3 45.8 2.6 3.2 7.7 38.5 1.1 3.1 3.4 2.9 4.6 10.8 9.1 7.7 5.3 4.3 2.7 3.7 2.1 1.0 0.7 2.9 0.0 1.0 0.5 4.1 2.8 1.6 1.2 0.0 30.9 1.3 0.6 6.0 14.8 7.0 1.3 2.3 2.9 5.7 21.9 43.7 30.0 3.0 2.0 0.8 2.5 1.8 32.9 4.6 10.6 5.6 1.5 8.8 0.0 4.0 15.2 1.4 3.5 22.2 1.5 4.0 0.4 2.4 4.8 11.4 0.0 5.4 3.2 0.4 2.3 3.6 3.4 0.7 0.9 1.9 2.9 2.0 HSPB3 HSPL27 ENSG00000169271 "Heat shock protein family B (small) member 3" Q12988 5 54455699-54456377 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Stress response" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 17 "heart muscle: 406.9;skeletal muscle: 217.2;tongue: 218.9" "Cell type enriched" "Detected in some" 18 "Cardiomyocytes: 398.1" "Cancer enriched" "Detected in many" 6 "head and neck cancer: 7.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 86.3;fHDF/TERT166: 39.1;HSkMC: 16.3;LHCN-M2: 12.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA062124 Supported "Nuclear speckles" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nuclear speckles" "HPA062124: AB_2684690" "unprognostic (1.44e-1)" "unprognostic (2.21e-1)" "unprognostic (1.78e-3)" "unprognostic (3.06e-1)" "unprognostic (2.25e-3)" "unprognostic (1.13e-1)" "unprognostic (4.41e-3)" "unprognostic (6.42e-2)" "unprognostic (1.85e-1)" "unprognostic (2.70e-2)" "unprognostic (2.73e-1)" "unprognostic (2.82e-2)" "unprognostic (7.15e-2)" 1.4 0.2 4.6 0.1 5.6 0.2 2.1 4.0 7.5 0.9 4.1 5.2 0.2 7.5 0.4 16.5 3.0 0.2 406.9 6.3 7.2 0.4 0.1 2.8 0.0 4.1 4.0 1.0 0.1 0.0 3.6 0.1 4.4 8.6 2.1 1.6 6.7 0.8 217.2 2.2 0.9 10.4 4.1 0.7 0.9 1.8 4.1 0.7 0.3 218.9 0.0 3.7 0.8 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 86.3 0.1 0.1 0.4 0.0 0.0 0.3 39.1 0.1 4.8 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.4 0.0 0.0 16.3 5.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 4.4 0.1 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.6 5.6 4.0 7.5 6.3 7.2 4.1 4.0 4.4 4.1 4.1 6.4 0.0 0.0 0.0 0.3 0.0 6.4 0.4 3.2 0.0 0.1 0.0 0.0 398.1 0.0 0.3 0.0 0.0 0.1 0.0 10.5 0.0 0.0 0.1 0.7 0.2 3.5 0.0 0.0 4.3 0.0 0.0 14.4 0.0 1.3 0.0 0.1 0.0 0.0 0.1 1.7 6.5 0.0 0.0 0.0 4.9 0.4 0.6 0.2 3.6 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.5 6.6 21.3 7.2 0.4 0.0 0.0 5.3 0.1 0.2 0.1 0.3 0.3 HTR7 5-HT7 ENSG00000148680 "5-hydroxytryptamine receptor 7" P34969 10 90740823-90858039 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, RAS pathway related proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 7.6;parathyroid gland: 13.1;testis: 8.7" "Cell type enhanced" "Detected in some" "Early spermatids: 7.0;Excitatory neurons: 5.9;Inhibitory neurons: 24.2;Spermatocytes: 13.1" "Group enriched" "Detected in some" 5 "cervical cancer: 0.9;head and neck cancer: 3.3;lung cancer: 0.9;urothelial cancer: 1.3" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 12 "myeloid DC: 1.4" "Lineage enriched" "Detected in single" 12 "dendritic cells: 1.4" "Cell line enhanced" "Detected in many" "HBEC3-KT: 11.3;hTCEpi: 10.1;hTERT-HME1: 33.4;LHCN-M2: 13.5;U-251 MG: 9.6;U-87 MG: 10.2;WM-115: 13.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB022708, HPA073617" Approved Supported Supported "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Nuclear speckles, Cytosol" "CAB022708: , HPA073617: AB_2732228" "unprognostic (1.17e-1)" "unprognostic (1.24e-2)" "unprognostic (4.72e-2)" "unprognostic (1.33e-1)" "unprognostic (5.51e-3)" "unprognostic (1.71e-2)" "unprognostic (1.89e-1)" "unprognostic (1.44e-1)" "unprognostic (1.15e-1)" "unprognostic (4.58e-3)" "unprognostic (3.32e-1)" "unprognostic (1.45e-1)" "unprognostic (2.89e-1)" "unprognostic (1.23e-3)" "unprognostic (1.38e-1)" "unprognostic (1.84e-2)" "unprognostic (6.49e-2)" 0.5 0.2 2.4 0.9 1.4 0.3 0.3 0.0 2.5 0.4 0.4 0.6 0.5 0.2 0.1 0.7 0.2 0.9 0.1 2.7 7.1 0.1 0.4 0.2 0.6 1.5 3.2 0.1 0.2 13.1 0.1 0.3 1.9 0.2 0.9 0.1 0.3 0.1 0.9 0.5 1.4 0.3 0.5 1.1 0.7 8.7 7.6 0.2 0.1 0.5 0.3 2.3 0.6 0.8 0.3 0.0 0.0 0.0 0.2 0.9 0.0 0.7 0.3 0.7 1.0 0.0 1.2 0.0 0.0 0.1 2.0 4.7 1.3 11.3 2.8 0.0 0.2 0.0 0.0 0.0 5.1 0.0 0.6 7.8 10.1 3.3 33.4 6.3 0.0 0.0 0.1 0.0 13.5 0.0 0.0 0.2 1.2 0.0 1.6 1.0 0.1 0.0 0.0 1.2 0.4 0.0 0.5 0.0 5.4 0.6 0.0 0.2 0.3 6.1 0.0 0.1 9.6 0.0 0.0 0.0 10.2 0.0 13.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.4 1.4 0.0 2.5 2.7 7.1 1.5 3.2 1.9 0.5 7.6 0.8 0.1 0.0 0.0 0.7 0.3 0.0 0.2 0.7 0.0 0.0 0.0 0.3 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.3 0.0 0.0 0.4 5.9 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.4 0.0 1.7 0.0 24.2 0.0 2.0 2.2 0.0 2.7 0.0 2.5 0.0 0.0 0.4 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.2 0.1 13.1 1.3 0.0 0.1 0.1 0.2 0.0 0.0 0.3 IFT57 "ESRRBL1, FLJ10147, HIPPI, MHS4R2" ENSG00000114446 "Intraflagellar transport 57" Q9NWB7 3 108160812-108222435 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" DNA-binding Ciliopathy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 1675.3;Late spermatids: 2795.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 41.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035514, HPA035515" Supported Approved "Nuclear speckles,Mitochondria,Cytosol" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 34: Spermatids - Unknown function" "Nuclear speckles" "Mitochondria, Cytosol" "HPA035514: AB_10601757, HPA035515: AB_10696505" "unprognostic (1.35e-2)" "unprognostic (1.37e-2)" "prognostic favorable (6.96e-5)" "unprognostic (2.98e-2)" "unprognostic (5.46e-3)" "unprognostic (1.02e-2)" "unprognostic (3.79e-2)" "unprognostic (3.61e-3)" "unprognostic (3.59e-2)" "prognostic favorable (7.63e-4)" "unprognostic (5.04e-2)" "unprognostic (2.78e-1)" "unprognostic (1.68e-3)" "unprognostic (1.86e-1)" "unprognostic (4.70e-2)" "unprognostic (8.67e-3)" "unprognostic (6.12e-2)" 8.9 15.3 11.6 8.6 11.7 13.2 13.1 10.2 15.5 11.7 14.8 13.3 6.0 13.3 45.1 8.5 32.0 13.4 10.4 11.4 11.5 21.3 4.5 40.7 17.3 12.0 12.2 14.0 13.8 23.0 16.3 7.8 11.6 27.5 14.6 24.0 9.1 17.5 4.2 8.6 9.0 10.6 11.9 12.1 9.8 42.8 12.0 8.2 26.1 4.4 16.4 13.9 8.3 11.8 35.5 17.2 12.8 23.1 26.1 26.9 7.1 10.6 25.8 15.3 13.6 12.4 6.1 39.5 13.3 17.8 22.0 13.9 11.5 17.8 25.8 6.2 12.2 13.6 8.0 3.3 19.4 28.5 30.2 16.3 16.1 19.9 34.2 24.4 17.5 6.6 6.4 6.9 17.8 18.9 9.5 25.8 13.6 2.7 21.0 6.1 11.5 6.3 31.6 12.3 21.1 14.7 15.9 5.2 9.9 7.1 11.0 8.3 7.5 19.6 10.2 10.5 12.6 8.1 6.2 20.7 28.4 2.7 7.3 0.2 3.5 3.1 3.6 6.5 5.8 41.9 7.4 4.5 10.2 34.9 6.2 3.7 1.8 6.8 12.8 2.0 5.1 4.9 11.6 11.7 10.2 15.5 11.4 11.5 12.0 12.2 11.6 11.9 12.0 11.8 36.6 471.1 291.2 18.6 98.4 41.0 114.1 72.9 34.7 25.6 42.2 50.9 33.8 58.6 201.9 51.5 68.8 22.3 16.9 51.1 117.4 158.8 1675.3 266.3 57.8 38.2 57.2 13.7 52.6 134.1 19.3 78.9 25.5 37.0 44.3 57.1 25.7 5.9 14.5 28.6 20.3 35.7 42.7 8.1 27.7 2795.4 65.3 19.3 46.2 4.7 13.1 56.8 8.2 13.0 13.5 79.4 36.6 64.3 40.2 151.4 24.3 124.5 528.7 72.7 52.6 61.7 61.3 242.2 43.6 25.4 37.2 14.9 30.2 104.9 52.3 93.0 IK "RED, RER" ENSG00000113141 "IK cytokine" Q13123 5 140647058-140662480 "Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 438.7;Endometrial ciliated cells: 510.8;Respiratory ciliated cells: 732.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048798 Supported Enhanced "Nuclear speckles" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 16: U-266 - Nucleosome" "Cluster 49: Ciliated cells - Cilium organization" "Nuclear speckles" "HPA048798: AB_2680525" "unprognostic (9.90e-2)" "prognostic favorable (1.29e-4)" "unprognostic (6.99e-2)" "unprognostic (1.49e-2)" "unprognostic (3.23e-1)" "unprognostic (2.44e-1)" "prognostic unfavorable (2.32e-7)" "unprognostic (1.19e-1)" "unprognostic (4.87e-2)" "unprognostic (4.37e-2)" "unprognostic (8.45e-2)" "unprognostic (2.81e-1)" "unprognostic (2.53e-3)" "unprognostic (3.76e-1)" "unprognostic (1.26e-1)" "unprognostic (3.26e-2)" "unprognostic (2.83e-1)" 73.9 64.0 53.4 68.7 56.6 135.4 66.9 64.4 70.8 70.0 62.3 76.1 55.4 73.9 74.4 77.0 143.5 53.4 74.2 54.2 68.6 67.0 68.6 69.5 89.9 60.6 60.6 78.8 48.3 74.3 55.8 64.9 59.9 60.3 70.3 90.4 65.2 66.2 136.5 73.4 67.9 64.6 57.0 71.6 60.5 107.7 57.6 114.0 72.6 83.0 96.0 69.6 68.1 62.3 119.1 132.5 114.4 163.2 125.7 106.4 133.4 139.0 146.7 151.6 153.2 184.1 133.4 138.9 167.4 145.4 172.3 120.9 168.2 190.1 175.4 198.1 136.6 130.4 213.2 117.8 129.6 214.6 136.9 117.2 124.4 151.5 136.8 112.0 132.7 114.9 144.3 121.1 137.3 110.0 184.1 216.8 74.5 100.3 134.2 145.5 160.7 141.4 117.7 109.2 103.6 112.3 171.5 155.6 172.9 97.9 181.3 171.8 141.2 126.2 87.9 106.2 167.8 181.8 294.1 188.4 141.8 162.4 94.5 353.1 136.5 240.3 188.3 157.1 168.9 197.4 202.7 194.3 139.0 191.5 212.7 199.1 229.4 198.8 193.0 131.2 284.4 247.0 53.4 56.6 64.4 70.8 54.2 68.6 60.6 60.6 59.9 57.0 57.6 62.3 110.7 163.5 134.9 10.1 102.8 46.1 86.4 127.5 61.5 75.3 40.0 57.7 126.7 80.1 177.1 86.5 29.2 115.2 139.9 69.2 121.3 106.4 438.7 510.8 124.9 91.4 34.1 137.6 7.6 99.6 99.6 82.6 50.0 107.2 132.2 68.0 54.3 74.7 70.6 53.8 8.2 66.4 97.6 56.8 58.8 55.0 98.2 80.2 56.9 8.4 107.4 116.1 151.4 8.5 7.4 110.1 67.3 83.8 76.9 50.5 80.4 120.8 732.0 97.3 72.3 96.0 115.7 311.3 145.0 65.3 45.5 132.8 128.5 93.0 65.5 66.9 IL15 "IL-15, MGC9721" ENSG00000164136 "Interleukin 15" P40933 4 141636583-141733987 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 78.0;monocytes: 72.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 17.6;Karpas-707: 18.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB004457, HPA037738" Approved Supported "Nucleoplasm,Nuclear speckles" "Secreted to blood" NA NA 182000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 20: HeLa - Mitochondria" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoplasm, Nuclear speckles" "CAB004457: AB_2124575, HPA037738: AB_2675640" "unprognostic (1.10e-2)" "unprognostic (1.53e-1)" "unprognostic (1.04e-2)" "unprognostic (8.57e-2)" "unprognostic (8.77e-3)" "unprognostic (1.69e-1)" "unprognostic (1.17e-1)" "unprognostic (2.90e-1)" "unprognostic (1.80e-1)" "unprognostic (1.48e-1)" "unprognostic (5.20e-2)" "unprognostic (1.74e-2)" "unprognostic (3.75e-2)" "unprognostic (1.09e-1)" "unprognostic (4.03e-2)" "unprognostic (3.29e-2)" "unprognostic (1.54e-1)" 7.7 3.4 1.3 7.1 1.4 4.0 6.0 2.1 1.8 5.3 1.4 7.7 6.1 4.5 2.5 4.4 4.5 4.9 5.1 1.2 1.3 7.9 3.6 7.8 9.7 2.3 1.3 1.5 2.7 0.7 3.6 3.1 1.8 4.1 5.3 4.3 3.6 2.7 8.6 3.4 10.0 4.6 1.5 15.4 4.8 2.5 1.8 6.8 15.6 3.4 6.6 4.5 6.4 1.9 2.8 6.3 0.3 0.6 0.9 5.4 1.6 6.7 6.1 6.8 5.5 3.4 8.1 2.5 8.5 6.2 6.0 4.4 0.1 3.4 3.6 17.6 1.7 0.5 16.7 0.5 4.5 1.9 1.3 2.1 1.5 4.4 0.5 13.7 4.3 2.3 4.0 18.8 4.2 0.9 4.2 0.3 3.3 2.3 1.7 1.0 16.0 0.5 9.2 0.8 0.6 1.6 3.1 4.7 3.2 0.8 0.9 0.3 6.6 6.9 4.3 2.0 4.2 13.0 1.8 1.0 7.2 0.8 2.5 10.4 16.1 0.6 2.7 15.1 5.0 4.1 3.3 2.5 5.5 4.0 1.4 1.4 1.2 3.2 16.5 0.2 2.0 6.1 1.3 1.4 2.1 1.8 1.2 1.3 2.3 1.3 1.8 1.5 1.8 1.9 14.8 0.0 2.8 0.3 9.9 6.1 2.5 2.1 2.2 0.6 2.1 1.3 2.9 2.8 5.3 5.5 0.0 1.2 5.0 4.7 0.0 9.4 6.6 6.9 78.0 14.8 0.0 1.3 2.0 14.0 1.6 5.5 4.1 5.9 0.0 0.9 11.4 2.5 4.7 0.0 4.8 5.4 0.0 17.0 22.1 2.5 2.8 16.7 8.8 4.7 72.0 21.1 8.2 3.0 0.2 19.8 8.2 1.2 9.3 6.2 9.9 12.0 3.9 0.9 6.6 7.6 4.0 1.2 0.8 5.6 3.4 0.3 6.0 0.1 2.6 3.0 IL16 "FLJ16806, FLJ42735, HsT19289, IL-16, LCF, prIL-16" ENSG00000172349 "Interleukin 16" Q14005 15 81159575-81314058 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Chemotaxis, Host-virus interaction, Transcription, Transcription regulation" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 135.3" "Cell type enhanced" "Detected in many" "B-cells: 135.3;dendritic cells: 78.1;Kupffer cells: 59.2;Langerhans cells: 94.4;NK-cells: 121.5;Plasma cells: 55.6;T-cells: 76.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 57.3" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 27.7;HEL: 29.4;HMC-1: 50.6;RPMI-8226: 51.0;U-266/70: 60.3;U-698: 25.8;U-937: 35.1" "Group enriched" "Detected in all" 11 "cerebellum: 54.5;hippocampal formation: 27.0" "Region enriched" "Detected in many" 12 "cerebellum: 48.8" "CAB005247, HPA018467, HPA048861" Enhanced Supported "Nuclear speckles,Plasma membrane,Cytosol" "Secreted to blood" NA NA 208000 7300 "Cluster 5: Granulocytes - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear speckles" "Plasma membrane, Cytosol" "CAB005247: AB_2124730, HPA018467: AB_1851642, HPA048861: " "unprognostic (8.23e-3)" "unprognostic (2.70e-3)" "unprognostic (1.97e-2)" "unprognostic (9.61e-4)" "unprognostic (2.01e-1)" "unprognostic (5.26e-4)" "unprognostic (2.63e-2)" "unprognostic (6.72e-3)" "unprognostic (2.25e-1)" "unprognostic (3.91e-1)" "unprognostic (1.47e-1)" "unprognostic (6.21e-2)" "unprognostic (3.16e-3)" "unprognostic (1.21e-1)" "unprognostic (3.23e-2)" "unprognostic (5.26e-2)" "unprognostic (1.29e-1)" 18.9 6.3 3.5 63.3 3.0 62.1 15.5 57.3 4.1 9.6 13.8 14.4 11.3 9.9 7.7 7.4 17.8 16.2 5.9 2.9 5.7 3.2 9.7 23.7 132.6 5.9 5.7 6.1 2.6 2.3 2.1 9.0 10.5 5.8 16.8 0.5 11.2 4.5 3.3 12.0 39.9 9.8 5.8 86.2 15.6 4.2 5.2 130.4 6.9 8.5 135.3 18.9 10.4 7.6 0.0 0.0 0.0 0.1 17.5 7.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 27.7 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.4 0.0 29.4 0.0 0.0 0.9 21.0 50.6 0.9 0.0 0.1 0.6 0.0 0.4 3.5 3.2 10.7 0.1 0.0 1.7 22.2 0.0 0.1 0.0 0.1 0.1 51.0 0.0 0.2 0.1 0.1 0.1 0.0 9.9 0.0 0.0 4.6 0.2 0.3 0.2 1.0 0.0 60.3 5.5 25.8 1.8 35.1 1.5 252.8 116.2 321.3 164.5 142.7 185.9 166.0 170.6 180.6 150.9 157.2 224.9 185.6 282.5 213.2 149.1 113.7 197.0 338.0 3.5 3.0 57.3 4.1 2.9 5.7 5.9 5.7 10.5 5.8 5.2 7.6 9.4 3.2 6.6 0.0 135.3 8.2 0.2 0.8 1.2 0.2 0.8 1.4 2.7 8.6 1.9 1.8 0.0 0.3 78.1 0.3 0.0 0.1 1.4 3.1 6.6 7.5 0.0 20.2 3.4 0.2 0.3 15.9 1.1 0.7 27.1 0.0 26.7 9.2 19.0 0.0 4.9 0.3 0.0 59.2 94.4 1.4 10.8 33.1 28.4 18.7 30.2 0.3 121.5 0.0 0.3 0.0 1.2 18.0 55.6 0.1 0.1 0.4 7.7 0.7 6.6 1.1 3.2 2.1 7.5 1.2 3.7 0.4 76.3 0.2 0.7 0.2 ILRUN "C6orf106, dJ391O22.4, FLJ22195" ENSG00000196821 "Inflammation and lipid regulator with UBA-like and NBR1-like domains" Q9H6K1 6 34587288-34696859 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 211.7" "Cell type enhanced" "Detected in some" "Adipocytes: 9.9;Cardiomyocytes: 73.7;Cytotrophoblasts: 13.7;dendritic cells: 11.8;Hofbauer cells: 15.6;Syncytiotrophoblasts: 21.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034489, HPA034490" Approved Supported "Nuclear speckles,Centrosome,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles" "Centrosome, Cytosol" "HPA034489: AB_10669991, HPA034490: AB_2674186" "unprognostic (3.76e-2)" "unprognostic (2.51e-1)" "unprognostic (7.71e-2)" "unprognostic (1.02e-2)" "unprognostic (1.41e-1)" "unprognostic (1.32e-1)" "unprognostic (8.40e-2)" "unprognostic (9.94e-2)" "unprognostic (7.57e-2)" "unprognostic (5.68e-2)" "unprognostic (3.55e-2)" "unprognostic (1.31e-1)" "unprognostic (1.08e-2)" "unprognostic (1.04e-1)" "unprognostic (1.25e-1)" "unprognostic (1.05e-1)" "unprognostic (1.53e-1)" 57.0 35.3 38.4 31.4 39.3 28.6 35.2 48.8 51.6 26.6 36.2 43.4 30.1 29.5 29.0 42.1 27.2 29.3 76.8 39.8 39.8 43.1 77.1 42.5 34.0 41.6 49.9 25.8 30.3 47.3 24.5 30.4 41.5 30.7 29.8 46.7 33.9 32.4 211.7 37.0 35.7 39.4 39.6 31.6 35.0 67.8 43.7 32.9 37.4 187.4 44.8 40.2 28.1 41.4 94.0 41.8 40.3 59.8 95.7 51.9 48.5 63.5 72.3 72.1 89.4 83.0 42.1 107.0 46.1 62.3 99.5 90.7 120.0 52.6 90.3 151.4 47.0 89.2 47.3 80.0 93.4 76.0 96.2 35.4 108.0 73.3 66.4 49.5 58.6 43.9 103.0 43.6 41.7 56.3 52.7 52.7 37.7 152.0 37.3 40.6 52.2 57.0 57.0 91.2 48.6 38.0 93.3 44.9 91.8 82.1 56.5 63.3 60.1 59.1 45.6 63.0 62.7 63.2 154.3 81.8 21.3 66.7 70.1 23.9 3.7 8.1 8.9 6.6 4.7 6.7 6.4 7.1 4.4 8.1 3.5 5.5 4.6 6.2 8.3 2.2 10.0 5.7 38.4 39.3 48.8 51.6 39.8 39.8 41.6 49.9 41.5 39.6 43.7 41.4 9.9 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 73.7 0.0 0.0 0.0 0.0 13.7 11.8 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 8.6 7.0 0.0 0.0 0.0 0.0 0.0 0.0 15.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 21.6 1.6 0.0 0.0 0.0 IPCEF1 "KIAA0403, PIP3-E" ENSG00000074706 "Interaction protein for cytohesin exchange factors 1" Q8WWN9 6 154154496-154356792 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "bone marrow: 17.7;brain: 13.6;lymphoid tissue: 13.5;thyroid gland: 39.1" "Cell type enhanced" "Detected in many" "dendritic cells: 46.1;Excitatory neurons: 120.0;Microglial cells: 252.9;T-cells: 65.5" "Cancer enhanced" "Detected in many" "thyroid cancer: 2.3" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 71.6" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 4 "HMC-1: 19.8;THP-1: 10.5;U-937: 11.0" "Low region specificity" "Detected in all" "HPA028708, HPA028710" Supported Approved "Nucleoli,Nuclear speckles,Plasma membrane,Cytoplasmic bodies" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles, Plasma membrane" "Nucleoli, Cytoplasmic bodies" "HPA028708: AB_10601916, HPA028710: AB_2732442" "unprognostic (1.23e-2)" "unprognostic (8.93e-3)" "unprognostic (4.18e-2)" "unprognostic (5.63e-3)" "unprognostic (2.05e-1)" "unprognostic (6.55e-3)" "unprognostic (1.30e-3)" "unprognostic (2.57e-2)" "unprognostic (3.87e-1)" "unprognostic (5.84e-2)" "unprognostic (3.27e-2)" "unprognostic (4.87e-2)" "unprognostic (5.01e-2)" "unprognostic (8.64e-2)" "unprognostic (5.45e-2)" "unprognostic (1.42e-2)" "unprognostic (1.51e-4)" 0.7 0.2 8.4 7.9 5.4 17.7 1.5 4.1 13.6 2.7 0.0 1.3 0.7 1.1 1.4 1.4 2.1 2.9 0.6 5.4 3.2 2.8 2.0 1.5 13.5 0.0 7.4 0.6 0.7 0.1 0.6 1.6 0.0 0.8 1.2 0.2 1.2 0.4 0.2 0.5 2.3 0.9 0.0 6.8 2.4 0.9 12.2 10.6 39.1 0.2 12.8 2.1 0.5 5.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.1 19.8 0.1 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 3.1 1.2 0.8 0.0 0.5 0.1 0.1 0.3 0.7 2.1 0.2 0.1 0.0 0.1 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 11.0 0.0 3.2 14.5 71.6 13.0 6.5 27.6 0.0 16.3 12.5 16.2 0.1 27.9 16.8 42.7 14.3 8.5 0.4 22.6 12.6 8.4 5.4 4.1 13.6 5.4 3.2 0.0 7.4 0.0 0.0 12.2 5.4 1.1 0.0 1.7 7.8 3.5 0.6 0.5 0.4 12.0 0.6 1.8 1.0 1.1 1.5 1.7 1.8 0.0 1.7 46.1 0.0 7.9 2.1 1.3 2.0 1.2 2.3 0.0 3.2 120.0 0.0 0.1 1.0 3.1 2.5 0.0 0.1 3.3 1.1 2.8 3.3 9.8 0.5 2.0 23.4 15.2 0.3 0.3 15.2 0.0 252.9 17.9 0.2 27.8 9.0 14.6 0.0 0.1 0.4 20.7 0.6 0.1 2.0 1.3 0.2 0.0 3.4 0.4 0.2 1.1 4.0 0.6 2.7 65.5 2.0 0.3 1.3 IQCK "FLJ36575, MGC35048" ENSG00000174628 "IQ motif containing K" Q8N0W5 16 19716456-19858467 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 128.3;Cone photoreceptor cells: 114.7;Respiratory ciliated cells: 98.7;Rod photoreceptor cells: 107.4;Spermatocytes: 101.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026792, HPA048786" Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 9: Photoreceptor cells - Phototransduction" "Nuclear speckles" Cytosol "HPA026792: AB_1853889, HPA048786: AB_2680520" "unprognostic (4.21e-2)" "unprognostic (3.19e-1)" "unprognostic (6.29e-3)" "unprognostic (2.04e-2)" "unprognostic (3.70e-1)" "unprognostic (4.07e-2)" "unprognostic (1.69e-1)" "unprognostic (8.51e-2)" "unprognostic (1.58e-1)" "unprognostic (9.68e-3)" "unprognostic (1.17e-1)" "unprognostic (5.13e-2)" "unprognostic (4.17e-3)" "unprognostic (2.42e-1)" "unprognostic (8.98e-2)" "unprognostic (6.51e-2)" "unprognostic (1.68e-1)" 3.8 2.7 5.3 1.3 5.7 0.5 5.9 5.2 6.8 7.5 8.7 2.6 3.8 4.6 15.4 1.6 20.2 5.7 3.5 5.1 8.7 8.7 2.1 4.0 1.5 6.2 7.2 6.5 3.6 19.4 6.3 3.2 5.7 3.4 2.9 11.0 6.4 7.6 3.0 2.1 1.6 3.8 6.8 1.8 3.9 18.2 5.6 1.6 16.8 2.9 1.1 4.1 2.0 8.0 2.6 6.8 8.7 5.7 2.6 8.1 0.5 0.0 4.4 4.0 3.1 0.4 4.8 0.3 4.7 2.4 2.5 3.0 1.9 3.3 2.8 1.1 1.8 0.1 1.9 3.4 8.2 1.6 0.0 4.7 2.7 5.4 1.2 4.5 4.4 4.2 2.8 0.8 2.5 8.5 1.6 0.9 2.6 2.8 6.4 5.3 0.8 0.4 10.0 1.8 8.1 3.4 3.9 1.2 5.3 1.6 3.6 0.9 3.1 1.1 0.9 4.6 0.9 0.1 0.6 0.0 5.4 0.2 1.9 0.0 0.3 0.0 0.5 1.3 0.9 0.5 0.5 0.8 0.1 0.2 1.0 0.5 0.0 0.0 1.3 0.3 0.5 0.3 5.3 5.7 5.2 6.8 5.1 8.7 6.2 7.2 5.7 6.8 5.6 8.0 42.4 16.0 5.1 128.3 1.7 6.1 9.7 16.4 9.6 54.1 18.3 16.5 0.7 24.3 17.8 46.0 114.7 4.9 1.3 8.6 46.9 47.2 57.2 76.9 19.0 22.1 5.4 0.8 31.9 29.6 2.8 11.8 12.8 14.9 0.0 6.2 11.7 2.1 6.0 3.3 45.9 4.3 32.6 2.4 3.9 34.8 18.0 3.7 17.8 15.0 1.5 26.3 0.0 37.2 53.4 29.8 2.2 18.0 2.3 7.3 2.0 32.5 98.7 107.4 6.6 7.5 15.6 101.7 35.8 3.9 5.1 4.1 3.0 18.1 6.7 5.1 IQUB FLJ35834 ENSG00000164675 "IQ motif and ubiquitin domain containing" Q8NA54 7 123452193-123535077 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 33.4" "Group enriched" "Detected in many" 7 "Early spermatids: 283.9;Endometrial ciliated cells: 82.6;Late spermatids: 157.5;Respiratory ciliated cells: 88.2;Spermatocytes: 116.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RPTEC TERT1: 2.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA049626 Approved "Nucleoplasm,Nuclear speckles,Intermediate filaments,Cytosol" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" "Nuclear speckles" "Nucleoplasm, Intermediate filaments, Cytosol" "HPA049626: AB_2732554" "unprognostic (8.71e-2)" "unprognostic (1.25e-2)" "unprognostic (1.98e-1)" "unprognostic (6.42e-4)" "unprognostic (1.91e-1)" "unprognostic (1.44e-2)" "unprognostic (6.23e-2)" "unprognostic (7.97e-2)" "unprognostic (1.46e-1)" "unprognostic (1.73e-1)" "unprognostic (2.40e-2)" "unprognostic (3.76e-1)" "unprognostic (5.44e-6)" "unprognostic (2.79e-1)" "unprognostic (9.78e-3)" "unprognostic (2.14e-1)" "unprognostic (7.30e-2)" 0.1 0.6 0.2 0.0 0.4 0.0 0.5 1.7 0.9 0.8 3.9 0.1 0.0 0.7 1.1 0.0 5.0 0.8 0.1 0.2 0.5 3.0 0.0 0.8 0.0 1.8 2.0 0.2 0.3 1.7 1.0 0.1 1.3 0.5 0.0 1.1 0.2 0.6 0.1 0.1 0.0 0.2 1.0 0.0 0.1 33.4 0.6 0.0 3.0 0.1 0.0 0.1 0.1 0.4 0.1 0.0 0.4 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.5 0.3 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 1.7 0.9 0.2 0.5 1.8 2.0 1.3 1.0 0.6 0.4 1.1 6.4 0.5 19.6 0.0 0.5 0.7 3.8 0.0 2.5 1.9 1.8 1.8 0.0 11.4 18.4 4.2 0.4 0.1 0.1 1.9 1.1 283.9 82.6 3.2 0.9 1.8 0.0 12.0 0.4 0.3 1.1 0.0 1.7 1.3 0.3 0.7 0.0 0.1 3.3 8.6 0.2 8.2 0.0 0.3 157.5 2.5 0.4 0.0 4.7 0.3 1.8 0.0 5.0 2.6 0.2 0.0 3.0 0.0 0.5 0.0 5.7 88.2 9.0 6.6 0.7 2.7 116.2 6.0 0.2 0.1 0.7 0.3 2.9 0.0 0.3 IRX5 IRX-2a ENSG00000176842 "Iroquois homeobox 5" P78411 16 54930865-54934485 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Sensory transduction, Transcription, Vision" DNA-binding "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 14.0;skin 1: 16.9" "Cell type enhanced" "Detected in many" "Breast glandular cells: 40.3;Breast myoepithelial cells: 55.5;Granulosa cells: 43.8;Muller glia cells: 43.1;Squamous epithelial cells: 33.9" "Cancer enhanced" "Detected in many" "breast cancer: 20.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 27.1;T-47d: 36.6;THP-1: 20.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA047130 Approved "Nuclear speckles,Microtubules,Cytosol" No NA "Cluster 31: Skin - Epidermis development" "Cluster 6: T47d - Mammary gland" "Cluster 40: Granulosa cells - Unknown function" "Nuclear speckles" "Microtubules, Cytosol" "HPA047130: AB_10962983" "unprognostic (2.63e-1)" "unprognostic (4.49e-2)" "unprognostic (8.03e-2)" "unprognostic (8.56e-2)" "unprognostic (1.42e-2)" "unprognostic (3.89e-2)" "unprognostic (5.38e-3)" "prognostic favorable (4.59e-4)" "unprognostic (8.52e-2)" "unprognostic (1.02e-1)" "unprognostic (1.56e-2)" "unprognostic (3.43e-2)" "unprognostic (1.17e-3)" "unprognostic (3.34e-2)" "unprognostic (8.90e-2)" "unprognostic (1.77e-3)" "unprognostic (4.28e-2)" 1.7 0.6 1.3 0.0 1.5 0.0 14.0 4.1 0.4 1.8 0.3 0.2 0.0 0.1 0.0 7.2 0.2 0.1 9.8 0.3 1.9 6.9 0.0 6.4 0.0 3.6 4.1 0.3 0.1 0.3 0.4 0.0 3.1 3.4 0.0 1.3 10.2 0.2 1.4 16.9 0.0 0.0 3.6 0.0 2.6 0.7 4.6 0.3 0.1 1.1 0.0 0.6 5.9 3.5 0.8 0.5 8.6 3.2 3.1 0.6 0.4 3.3 8.2 1.1 0.8 1.9 0.8 0.0 0.7 4.5 0.3 8.4 3.0 3.6 0.6 6.0 4.1 0.9 3.4 0.0 0.1 2.0 3.3 0.8 15.1 5.4 2.3 1.5 0.0 4.8 0.5 0.0 6.2 3.3 9.6 12.3 0.1 1.3 2.4 5.0 4.4 0.5 27.1 0.2 2.9 3.0 1.4 7.3 3.9 0.0 36.6 20.2 0.5 5.9 0.2 4.2 1.3 3.6 2.3 2.9 9.6 3.9 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.5 4.1 0.4 0.3 1.9 3.6 4.1 3.1 3.6 4.6 3.5 2.4 9.6 21.9 0.0 0.1 8.3 9.7 6.7 15.9 8.6 40.3 55.5 11.1 0.0 15.4 0.0 0.0 0.2 1.0 0.2 0.0 0.3 1.0 9.6 1.2 1.6 0.0 0.0 0.0 0.6 0.0 5.3 7.7 12.2 0.0 43.8 0.0 0.0 0.2 1.7 0.0 0.8 4.1 0.0 2.7 2.4 0.0 0.6 5.4 0.0 0.0 43.1 0.0 0.0 0.0 2.9 0.3 0.0 0.3 4.8 0.0 1.5 13.0 1.9 0.0 8.3 5.2 0.7 2.8 33.9 8.0 0.0 0.4 0.0 0.5 8.5 ISL1 "Isl-1, ISLET1" ENSG00000016082 "ISL LIM homeobox 1" P61371 5 51383448-51394730 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 22.9;seminal vesicle: 19.2;vagina: 15.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 207.5;Cytotrophoblasts: 34.4;Enteroendocrine cells: 91.6;Horizontal cells: 43.7;Syncytiotrophoblasts: 34.2" "Group enriched" "Detected in some" 5 "cervical cancer: 1.1;pancreatic cancer: 4.1;prostate cancer: 2.1;stomach cancer: 1.6;testis cancer: 1.4" "Group enriched" "Detected in many" 5 "hypothalamus: 11.5;thalamus: 6.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 16 "SH-SY5Y: 297.1" "Group enriched" "Detected in many" 8 "basal ganglia: 13.8;hypothalamus: 15.0;thalamus: 6.0" "Group enriched" "Detected in some" 9 "basal ganglia: 5.8;hypothalamus: 5.4" "HPA048613, HPA057416" Approved Approved "Nucleoplasm,Nuclear speckles,Mitochondria" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm "Nuclear speckles, Mitochondria" "HPA048613: , HPA057416: AB_2683431" "unprognostic (4.97e-2)" "unprognostic (2.22e-2)" "unprognostic (1.69e-1)" "unprognostic (2.41e-3)" "unprognostic (5.52e-2)" "unprognostic (6.79e-2)" "unprognostic (9.21e-2)" "unprognostic (9.42e-2)" "unprognostic (5.55e-3)" "unprognostic (1.77e-1)" "unprognostic (1.48e-1)" "unprognostic (2.48e-1)" "unprognostic (9.11e-3)" "unprognostic (4.39e-3)" 2.9 1.3 0.4 0.0 1.4 0.0 0.1 0.0 1.8 7.8 0.0 1.1 2.3 0.1 0.1 0.1 0.0 0.0 0.0 0.0 11.5 0.0 0.0 0.0 0.0 1.0 0.5 0.0 4.8 0.0 2.2 7.8 1.2 12.0 2.4 22.9 1.1 19.2 0.0 1.1 0.7 0.1 0.0 0.0 10.0 1.6 6.0 4.3 0.3 0.0 0.4 0.7 15.9 0.2 0.0 0.0 0.0 3.4 0.0 0.0 0.2 3.0 3.8 0.0 0.0 0.3 2.7 0.0 2.5 0.0 0.0 2.2 4.6 3.4 0.0 0.0 7.1 0.0 12.6 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.3 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.9 3.2 0.0 3.0 0.0 0.0 0.0 19.1 297.1 0.0 0.0 0.0 11.6 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.4 0.0 1.8 0.0 11.5 1.0 0.5 1.2 0.0 6.0 0.2 0.0 0.0 0.0 0.0 0.1 1.5 5.1 11.8 0.0 207.5 0.0 0.0 0.2 0.0 2.8 0.0 4.2 34.4 0.0 0.5 0.0 0.1 17.3 0.0 0.0 1.7 91.6 0.0 0.0 0.0 10.9 6.1 11.7 0.0 0.0 0.0 0.0 0.0 2.7 43.7 0.0 1.9 8.2 0.0 0.4 3.2 0.3 0.1 0.0 0.0 0.0 4.1 0.0 0.0 0.0 4.2 0.0 0.0 0.0 1.1 0.0 0.0 0.8 11.8 0.0 0.0 4.0 2.5 7.3 0.0 1.0 34.2 0.0 0.0 0.2 5.6 ISY1 "fSAP33, KIAA1160" ENSG00000240682 "ISY1 splicing factor homolog" Q9ULR0 3 129127415-129161063 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA006312, HPA016995" Supported Enhanced "Nuclear speckles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 14: REH - Unknown function" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nuclear speckles" "HPA006312: AB_1079734, HPA016995: AB_1852387" "unprognostic (2.20e-2)" "prognostic favorable (2.46e-5)" "unprognostic (1.46e-2)" "unprognostic (1.84e-3)" "unprognostic (2.19e-1)" "unprognostic (5.52e-2)" "prognostic unfavorable (7.25e-4)" "unprognostic (4.08e-1)" "unprognostic (5.94e-2)" "unprognostic (7.38e-2)" "unprognostic (1.71e-1)" "unprognostic (7.34e-2)" "unprognostic (2.23e-3)" "unprognostic (2.49e-3)" "unprognostic (1.65e-1)" "unprognostic (1.66e-1)" "unprognostic (2.54e-2)" 18.7 13.7 9.1 19.0 9.0 51.6 17.0 9.8 9.6 20.2 7.5 21.6 15.4 19.5 15.1 22.2 15.5 17.4 21.4 8.8 9.1 15.0 10.8 14.1 32.0 9.2 9.3 19.7 15.8 11.2 8.8 22.1 8.9 13.3 16.9 10.4 15.0 12.3 34.9 20.3 16.2 20.3 8.2 18.2 14.9 12.4 8.8 22.7 14.9 21.3 30.1 18.3 19.4 8.9 53.7 20.5 29.6 41.6 35.1 36.4 34.5 39.3 35.0 46.1 44.2 40.6 39.3 67.3 41.3 32.6 40.0 44.8 56.3 31.8 64.9 65.0 26.5 78.0 35.2 32.8 32.7 121.2 53.4 22.9 21.7 40.6 62.3 28.7 37.7 43.2 57.1 33.5 25.2 54.2 73.8 67.1 32.3 55.9 31.3 64.9 67.3 47.5 17.3 33.5 46.8 35.3 72.7 15.7 41.9 16.0 30.3 99.1 45.2 33.5 33.4 49.8 41.6 40.1 26.1 131.9 30.8 69.4 39.0 79.8 57.6 94.2 54.8 56.4 61.4 56.1 55.8 58.7 62.8 50.7 61.0 55.0 90.7 84.8 51.2 54.5 73.5 56.5 9.1 9.0 9.8 9.6 8.8 9.1 9.2 9.3 8.9 8.2 8.8 8.9 26.5 25.6 23.4 0.0 27.4 27.4 16.5 21.3 20.5 19.7 17.0 15.6 19.7 21.5 21.8 9.2 22.9 44.1 38.5 15.8 23.5 26.7 2.8 11.9 23.0 25.3 9.0 29.0 0.0 28.0 41.2 21.8 12.8 21.0 45.6 25.8 26.0 12.3 34.8 20.2 0.0 16.7 16.2 21.1 25.6 1.8 16.1 23.9 10.6 0.0 43.7 20.7 46.4 0.0 0.0 24.4 15.3 16.1 24.1 17.4 18.8 23.2 14.8 19.0 19.7 18.8 20.9 57.4 42.6 20.0 35.8 45.8 32.9 18.7 20.5 16.9 ISY1-RAB43 ENSG00000261796 "ISY1-RAB43 readthrough" 3 129087575-129161036 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Excitatory neurons: 1.5;granulocytes: 1.3;Oligodendrocytes: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "HPA006312, HPA016995" Approved Enhanced "Nuclear speckles" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 34: Non-specific - Transcription" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 11: Alveolar cells - Smell perception" "Nuclear speckles" "HPA006312: AB_1079734, HPA016995: AB_1852387" "unprognostic (1.09e-1)" "unprognostic (5.42e-2)" "unprognostic (1.52e-1)" "unprognostic (9.05e-3)" "unprognostic (2.81e-1)" "unprognostic (3.15e-1)" "unprognostic (1.63e-1)" "unprognostic (2.52e-1)" "unprognostic (1.51e-3)" "unprognostic (1.89e-1)" "unprognostic (1.40e-1)" "unprognostic (5.67e-2)" "unprognostic (1.87e-1)" 7.6 7.2 2.4 10.1 2.8 7.1 7.5 2.4 5.7 7.3 2.5 7.6 3.9 8.1 4.4 5.2 6.9 4.2 5.7 2.3 2.9 7.8 9.6 9.4 8.1 2.5 2.6 9.4 7.2 8.8 5.6 6.5 3.2 7.6 7.4 2.7 6.6 8.3 3.9 5.5 6.7 7.7 2.1 9.2 6.8 5.1 2.7 16.7 7.6 3.7 9.0 7.6 4.6 3.5 26.1 5.7 12.9 11.9 15.8 9.3 5.6 12.2 28.5 19.4 23.6 3.0 13.1 0.9 17.7 22.0 22.2 9.8 5.1 20.4 11.9 9.9 1.0 2.4 2.5 10.2 27.1 10.8 12.9 21.5 10.7 12.1 7.7 19.2 25.4 23.7 4.2 9.9 16.9 10.8 16.3 7.7 9.1 27.7 6.7 13.7 5.6 9.1 20.8 9.9 0.9 5.8 5.8 13.1 18.9 10.7 6.5 10.3 21.0 9.4 7.9 13.5 5.6 14.3 7.0 4.4 10.7 1.1 13.3 0.1 0.5 0.1 0.6 0.2 0.6 0.0 0.6 0.8 0.2 0.1 0.8 0.7 0.6 0.6 0.4 0.2 0.4 0.6 2.4 2.8 2.4 5.7 2.3 2.9 2.5 2.6 3.2 2.1 2.7 3.5 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.5 0.0 0.0 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 ITGA7 ENSG00000135424 "Integrin subunit alpha 7" Q13683 12 55684568-55716043 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Cell shape" "Integrin, Receptor" "Congenital muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 262.3" "Group enriched" "Detected in many" 6 "Astrocytes: 87.5;Cardiomyocytes: 124.5;Sertoli cells: 164.3;Skeletal myocytes: 65.8;Smooth muscle cells: 110.6" "Cancer enhanced" "Detected in all" "glioma: 35.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "hTERT-RPE1: 309.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008427 Uncertain Approved "Nuclear speckles,Vesicles,Plasma membrane" NA NA 1200000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "Nuclear speckles, Vesicles" "HPA008427: AB_1851823" "unprognostic (4.71e-2)" "unprognostic (1.55e-1)" "unprognostic (2.00e-3)" "unprognostic (3.02e-3)" "unprognostic (2.50e-1)" "unprognostic (2.36e-1)" "unprognostic (1.66e-2)" "unprognostic (2.20e-1)" "unprognostic (2.20e-2)" "unprognostic (3.57e-1)" "prognostic favorable (1.75e-4)" "unprognostic (2.85e-2)" "unprognostic (5.89e-2)" "unprognostic (1.79e-1)" "unprognostic (5.10e-1)" "unprognostic (2.98e-2)" "prognostic unfavorable (9.59e-5)" 133.4 8.2 18.5 18.5 21.2 1.8 69.0 15.9 30.2 28.7 16.1 97.8 17.7 45.5 12.3 23.9 56.1 30.8 157.9 34.5 17.8 11.5 10.2 15.5 6.4 21.2 21.1 19.1 5.1 6.1 12.6 1.9 20.3 33.9 8.9 2.4 14.9 37.3 262.3 16.0 27.4 95.2 16.4 10.2 35.2 8.9 23.8 3.4 26.1 154.1 3.3 46.5 25.5 21.0 0.2 4.1 7.5 12.3 66.5 13.4 0.7 5.4 8.7 11.7 11.8 8.4 6.5 2.3 7.4 3.4 0.9 1.1 5.1 0.3 10.0 0.2 3.8 0.8 2.8 3.2 0.5 0.3 2.7 19.1 0.2 64.2 0.3 309.1 0.2 2.2 0.9 1.6 37.8 5.3 0.3 3.1 20.9 1.7 0.4 0.1 28.7 0.6 0.2 0.2 0.9 2.8 0.6 0.2 48.0 4.0 0.9 13.9 0.0 1.3 12.4 0.8 8.4 3.2 2.2 0.9 57.8 8.2 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 18.5 21.2 15.9 30.2 34.5 17.8 21.2 21.1 20.3 16.4 23.8 21.0 11.9 0.0 0.0 87.5 0.3 1.9 0.5 0.1 0.6 2.4 1.2 3.4 124.5 2.8 0.0 1.8 4.2 0.0 0.3 0.7 0.0 0.3 0.3 1.1 1.2 9.5 7.7 0.4 17.6 0.0 0.1 5.0 0.5 1.1 0.0 6.2 0.7 1.4 0.6 0.0 9.4 1.8 0.0 1.9 2.7 0.1 6.5 2.2 3.6 9.4 0.0 3.4 0.0 6.6 3.7 0.3 0.1 6.4 0.1 0.8 2.6 0.8 0.1 0.6 164.3 65.8 110.6 4.1 2.9 0.7 2.3 0.1 0.5 0.3 0.9 0.3 ITPKC "IP3-3KC, IP3KC" ENSG00000086544 "Inositol-trisphosphate 3-kinase C" Q96DU7 19 40717112-40740860 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 96.7" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 151.4;Glandular and luminal cells: 139.3;Squamous epithelial cells: 160.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTCEpi: 46.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050760, HPA053003" Approved Supported "Nuclear speckles" No No "Cluster 10: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" "Nuclear speckles" "HPA050760: AB_2681227, HPA053003: AB_2682011" "unprognostic (4.27e-2)" "unprognostic (3.73e-2)" "unprognostic (8.31e-2)" "unprognostic (9.12e-3)" "unprognostic (1.10e-2)" "unprognostic (9.81e-2)" "unprognostic (6.06e-2)" "prognostic unfavorable (4.91e-4)" "unprognostic (1.48e-1)" "unprognostic (1.54e-3)" "unprognostic (1.84e-3)" "unprognostic (2.63e-1)" "unprognostic (2.59e-1)" "unprognostic (1.70e-1)" "unprognostic (2.86e-2)" "unprognostic (3.45e-2)" "unprognostic (3.32e-1)" 45.3 13.9 11.2 10.8 9.6 3.5 29.4 9.4 10.7 32.6 11.6 16.8 11.7 18.6 4.7 96.7 25.0 23.0 19.3 10.0 10.7 18.8 17.7 41.8 6.0 15.0 11.5 12.9 22.8 10.3 22.0 10.3 11.6 27.1 6.8 5.5 31.1 10.5 18.4 51.0 16.9 16.3 10.8 14.5 26.3 6.0 15.2 8.7 17.2 8.9 13.9 22.4 42.0 9.3 12.9 12.0 7.3 11.5 32.2 27.8 11.6 7.5 15.7 7.6 6.7 17.3 13.1 3.5 8.5 9.7 5.7 13.3 7.3 32.6 3.1 6.7 7.5 2.7 4.5 12.3 31.8 3.0 3.6 38.8 46.4 7.2 26.5 10.3 18.9 5.0 10.6 6.1 7.5 15.7 4.4 4.5 3.7 29.4 5.4 4.7 3.6 4.9 12.0 21.5 5.2 6.5 7.6 30.5 7.2 8.4 14.1 7.6 12.2 4.9 7.3 3.3 5.1 3.5 0.9 3.7 7.6 3.1 5.4 0.9 0.7 0.4 0.8 0.3 0.3 0.3 0.6 0.4 0.3 0.7 0.4 0.5 0.3 0.2 0.5 0.5 0.6 0.4 11.2 9.6 9.4 10.7 10.0 10.7 15.0 11.5 11.6 10.8 15.2 9.3 75.4 86.6 35.2 6.5 2.7 60.4 72.4 17.4 39.9 10.0 88.4 44.4 4.1 7.2 29.7 3.7 0.0 7.7 2.8 57.7 1.9 13.9 2.1 67.5 23.2 26.4 16.7 3.2 7.4 12.3 5.5 20.1 151.4 139.3 3.8 4.3 25.7 6.8 2.9 5.0 6.0 27.2 2.0 7.8 9.6 2.2 11.8 6.8 19.6 6.5 3.1 3.7 3.1 9.0 3.5 23.2 50.8 7.5 1.2 65.3 28.7 4.4 29.4 6.2 0.0 7.1 10.1 1.9 2.0 160.8 53.4 16.8 5.2 4.6 18.0 98.6 JDP2 JUNDM2 ENSG00000140044 "Jun dimerization protein 2" Q8WYK2 14 75427716-75474111 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 70.7;Kupffer cells: 87.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 11.8;granulocytes: 7.7;monocytes: 13.2" "Cell line enhanced" "Detected in many" "HHSteC: 167.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059511 Supported Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nuclear speckles" "HPA059511: AB_2684046" "unprognostic (3.19e-2)" "unprognostic (5.58e-2)" "prognostic unfavorable (8.58e-5)" "unprognostic (1.64e-2)" "unprognostic (2.13e-1)" "unprognostic (1.20e-1)" "unprognostic (2.99e-2)" "unprognostic (2.81e-1)" "unprognostic (5.06e-2)" "unprognostic (1.91e-1)" "unprognostic (3.25e-2)" "unprognostic (1.86e-1)" "unprognostic (8.11e-3)" "unprognostic (2.20e-1)" "unprognostic (1.92e-1)" "unprognostic (2.13e-1)" "unprognostic (9.30e-3)" 53.5 20.0 23.2 29.3 22.0 78.6 40.2 22.8 28.2 31.6 22.0 31.6 22.5 22.7 3.7 25.4 28.5 27.7 39.1 23.5 24.2 18.9 20.5 47.2 13.1 24.6 22.9 21.6 23.1 8.1 17.3 17.5 22.6 21.8 11.3 16.4 24.2 15.0 21.9 29.1 30.1 20.9 22.6 66.8 23.3 4.7 25.4 4.8 25.1 16.7 10.6 25.3 31.6 21.8 15.5 13.5 2.5 26.8 81.5 60.2 90.5 47.5 51.0 30.4 38.1 33.0 13.5 12.4 23.5 90.7 5.6 59.5 16.7 16.2 13.1 16.7 1.9 17.0 26.0 11.9 167.1 24.1 1.3 106.5 95.2 12.4 30.6 11.9 1.5 13.8 2.2 23.0 27.7 76.4 1.4 39.8 9.1 30.4 8.7 8.2 0.3 34.0 14.8 8.6 2.1 10.4 48.9 69.4 55.1 29.7 66.4 52.1 6.2 38.1 57.5 2.4 7.0 18.7 6.0 28.8 11.5 90.0 19.1 0.1 4.5 4.4 0.0 8.1 0.0 11.8 0.2 0.0 2.4 5.1 0.0 0.0 7.7 0.1 13.2 2.1 0.2 1.4 23.2 22.0 22.8 28.2 23.5 24.2 24.6 22.9 22.6 22.6 25.4 21.8 70.7 12.8 33.5 26.8 9.9 16.4 6.0 5.8 19.9 21.8 26.2 18.2 17.7 12.8 8.1 9.2 10.4 1.4 1.2 20.0 0.0 2.4 0.3 21.6 18.4 21.2 5.4 0.8 18.9 6.6 5.6 49.5 10.2 23.9 2.5 10.1 10.4 8.5 9.7 8.4 20.8 14.9 4.1 87.7 25.7 1.5 18.0 47.3 12.4 14.0 13.8 38.6 2.1 18.1 3.0 8.5 8.2 16.6 9.8 2.6 17.7 3.0 7.4 31.1 6.6 47.2 19.5 0.1 0.9 19.7 8.9 0.3 2.2 5.3 8.7 11.5 KAT6A "MOZ, MYST3, RUNXBP2, ZC2HC6A, ZNF220" ENSG00000083168 "Lysine acetyltransferase 6A" Q92794 8 41929479-42051994 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, Repressor, Transferase" "Cancer-related genes, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017023, HPA063266, HPA065052" Supported Supported "Nucleoli,Nuclear speckles,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles" "Nucleoli, Cytosol" "CAB017023: , HPA063266: AB_2684973, HPA065052: AB_2685414" "unprognostic (3.51e-2)" "unprognostic (1.14e-1)" "unprognostic (2.04e-1)" "unprognostic (3.23e-2)" "unprognostic (2.28e-1)" "unprognostic (9.27e-3)" "unprognostic (3.61e-1)" "unprognostic (2.29e-1)" "unprognostic (2.95e-1)" "unprognostic (2.45e-2)" "unprognostic (1.50e-1)" "unprognostic (4.45e-2)" "unprognostic (4.20e-3)" "unprognostic (1.18e-1)" "unprognostic (2.24e-1)" "unprognostic (8.58e-2)" "unprognostic (2.95e-2)" 14.4 7.1 8.6 15.4 12.7 38.2 12.3 20.1 10.5 13.7 9.7 10.2 9.6 15.6 8.6 13.4 12.0 11.2 9.1 9.1 12.8 9.1 10.0 16.7 16.8 12.7 12.4 21.5 11.7 18.0 6.7 14.9 12.9 11.0 10.6 18.1 9.6 9.7 13.1 16.6 12.1 13.5 8.2 15.7 11.3 11.4 10.1 27.0 14.2 16.0 17.2 12.0 10.7 16.7 19.6 23.2 34.8 21.8 17.8 20.3 9.8 15.4 20.6 17.9 14.2 16.3 11.5 33.4 13.4 19.0 19.5 17.3 27.3 18.6 23.2 16.1 14.4 60.4 14.2 10.3 14.8 27.3 23.6 17.1 19.1 20.4 24.8 14.5 18.8 29.7 36.6 24.2 16.0 10.4 59.9 9.4 12.8 20.4 8.1 37.7 39.1 9.9 11.0 27.1 17.6 16.7 15.8 12.4 13.8 15.8 26.3 12.9 25.5 21.6 15.3 21.1 15.5 16.8 22.1 33.8 12.6 14.1 17.3 2.5 0.8 1.8 1.6 0.9 1.6 1.4 1.6 2.1 0.6 1.6 1.9 1.8 5.1 1.9 0.9 1.1 1.9 1.2 8.6 12.7 20.1 10.5 9.1 12.8 12.7 12.4 12.9 8.2 10.1 16.7 87.5 35.3 34.9 64.0 54.0 50.3 24.2 15.5 18.2 54.8 31.7 25.5 23.7 18.6 25.3 12.9 54.2 14.4 61.5 23.2 3.9 14.2 2.6 30.3 47.5 56.7 24.7 31.2 62.8 11.8 17.0 32.4 21.4 44.8 35.4 31.9 43.5 25.3 17.0 58.9 76.6 24.9 10.2 44.2 34.5 4.8 28.3 43.7 23.2 120.9 30.3 27.9 61.8 93.5 129.2 15.7 20.2 23.0 38.7 30.7 22.9 10.6 22.8 44.9 19.7 49.3 34.6 37.8 37.0 23.0 61.2 21.1 61.4 19.7 19.3 27.2 KATNIP "JBTS26, KIAA0556" ENSG00000047578 "Katanin interacting protein" O60303 16 27550133-27780369 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 2.7;Cardiomyocytes: 4.5;Cytotrophoblasts: 3.0;dendritic cells: 1.4;Extravillous trophoblasts: 2.6;Hofbauer cells: 2.6;Syncytiotrophoblasts: 2.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 14.3;eosinophil: 3.6;neutrophil: 9.9;NK-cell: 5.0" "Group enriched" "Detected in all" 5 "granulocytes: 14.3;NK-cells: 5.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035089, HPA035090" Enhanced Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles" "Plasma membrane" "HPA035089: AB_10671509, HPA035090: AB_10601129" "unprognostic (1.81e-1)" "unprognostic (1.13e-1)" "unprognostic (1.55e-1)" "unprognostic (3.65e-3)" "unprognostic (7.76e-2)" "prognostic favorable (3.00e-4)" "unprognostic (2.72e-2)" "unprognostic (3.58e-2)" "unprognostic (2.02e-1)" "unprognostic (1.22e-1)" "unprognostic (2.94e-1)" "unprognostic (2.12e-1)" "unprognostic (1.47e-3)" "unprognostic (2.98e-1)" "unprognostic (2.11e-1)" "unprognostic (1.50e-3)" "unprognostic (1.45e-1)" 4.4 4.8 5.2 4.7 5.9 6.7 5.4 3.9 6.9 6.3 22.7 6.5 4.8 6.3 6.2 9.7 29.7 5.1 5.4 5.4 4.1 7.8 4.0 6.3 4.4 6.7 7.8 5.1 9.0 7.7 11.5 4.4 4.9 8.8 7.2 31.3 7.9 5.7 3.3 8.9 6.0 5.5 4.9 6.2 9.3 9.9 6.3 5.6 15.9 1.7 4.0 5.3 5.8 6.6 6.7 13.5 7.5 7.0 11.1 10.1 12.4 8.9 9.6 7.7 10.4 12.0 10.9 5.7 12.4 12.8 15.0 11.0 9.7 11.5 15.4 26.5 6.7 4.5 14.9 7.0 6.6 6.1 11.0 10.8 9.9 17.1 18.2 10.0 15.5 6.3 7.3 4.7 11.1 15.3 6.7 7.5 4.6 8.6 5.5 9.6 9.1 6.2 14.5 9.2 9.5 6.1 8.9 7.9 5.0 10.3 17.8 5.3 13.5 9.8 6.2 7.7 7.9 6.3 5.7 6.4 11.3 5.9 8.9 14.3 1.8 3.6 0.7 1.2 0.7 0.8 0.4 1.2 1.2 1.1 1.6 0.3 9.9 5.0 0.4 1.4 1.6 0.3 5.2 5.9 3.9 6.9 5.4 4.1 6.7 7.8 4.9 4.9 6.3 6.6 2.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 3.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.2 0.4 0.0 0.0 0.0 KAZN "C1orf196, FLJ43806, KAZRIN, KIAA1026" ENSG00000189337 "Kazrin, periplakin interacting protein" Q674X7 1 13892792-15118043 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 91.5" "Group enriched" "Detected in many" 12 "Excitatory neurons: 1065.9;Inhibitory neurons: 2872.7;Oligodendrocyte precursor cells: 1360.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 23 "neutrophil: 3.4" "Lineage enriched" "Detected in single" 23 "granulocytes: 3.4" "Cell line enhanced" "Detected in many" "AN3-CA: 85.6;SK-BR-3: 46.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032095, HPA032096" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nuclear speckles, Cytosol" "HPA032095: AB_2674146, HPA032096: AB_10670826" "unprognostic (2.81e-1)" "unprognostic (5.82e-2)" "unprognostic (1.12e-1)" "unprognostic (2.42e-3)" "unprognostic (5.34e-2)" "unprognostic (2.15e-3)" "unprognostic (6.57e-3)" "unprognostic (7.88e-3)" "unprognostic (3.21e-1)" "unprognostic (4.96e-3)" "unprognostic (1.10e-1)" "unprognostic (5.55e-2)" "prognostic favorable (1.20e-6)" "unprognostic (3.61e-2)" "unprognostic (7.93e-2)" "unprognostic (3.21e-1)" "unprognostic (1.06e-2)" 12.6 17.7 27.3 3.0 31.5 0.6 11.4 43.6 33.6 17.0 23.9 5.5 5.1 4.2 12.2 34.9 12.6 7.7 6.9 25.0 24.1 24.9 5.8 16.5 1.0 37.1 32.9 16.7 9.2 29.5 5.1 6.3 32.7 7.5 3.9 12.9 21.4 7.4 1.4 23.5 5.3 3.6 29.2 91.5 5.1 4.5 34.1 1.9 10.3 1.6 5.5 8.9 21.3 47.1 17.7 3.0 18.5 85.6 7.9 8.2 6.3 8.3 6.9 15.0 10.8 4.0 9.3 0.0 21.1 17.8 2.7 6.3 4.3 13.5 7.5 0.5 8.4 10.1 10.2 26.6 5.8 0.0 5.0 11.6 17.7 3.5 2.3 6.8 0.1 2.5 4.2 19.8 12.2 12.8 0.1 1.1 5.1 7.9 2.6 6.0 0.4 10.6 25.5 5.4 9.8 7.1 1.5 46.3 33.0 10.5 2.8 6.7 0.0 12.4 11.6 19.8 10.1 3.3 3.0 0.0 11.6 17.4 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 27.3 31.5 43.6 33.6 25.0 24.1 37.1 32.9 32.7 29.2 34.1 47.1 17.6 3.2 1.8 124.1 0.9 50.3 16.6 9.7 31.3 12.4 23.0 27.9 3.4 4.3 9.1 49.7 8.4 1.5 0.9 12.3 17.6 2.0 6.8 51.4 15.8 19.4 7.1 0.0 1065.9 1.6 8.1 27.0 3.6 16.8 3.8 9.7 31.1 0.1 0.8 0.0 2872.7 5.2 18.3 0.9 11.4 9.1 19.0 1.1 46.2 93.7 0.0 74.2 4.1 1360.7 143.5 1.5 1.6 17.3 0.3 19.4 2.0 12.9 30.3 3.2 6.6 33.5 23.6 0.3 3.2 26.2 90.4 46.4 1.4 41.6 3.5 24.8 KCNK13 "K2p13.1, THIK-1, THIK1" ENSG00000152315 "Potassium two pore domain channel subfamily K member 13" Q9HB14 14 90061994-90185853 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 5.6;parathyroid gland: 6.0;testis: 9.2" "Cell type enriched" "Detected in some" 4 "Microglial cells: 41.2" "Cancer enhanced" "Detected in many" "testis cancer: 5.3" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.2" "Lineage enhanced" "Detected in single" "dendritic cells: 1.2" "Cell line enhanced" "Detected in some" "GAMG: 1.0;RT4: 1.9;SuSa: 2.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA003514 Approved Approved "Nuclear speckles,Cell Junctions" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 15: RT4 - Unknown function" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles, Cell Junctions" "HPA003514: AB_2666978" "unprognostic (1.40e-1)" "unprognostic (1.73e-1)" "unprognostic (6.17e-2)" "unprognostic (6.31e-2)" "unprognostic (2.56e-1)" "unprognostic (5.55e-2)" "unprognostic (3.56e-2)" "unprognostic (3.98e-2)" "unprognostic (2.40e-1)" "unprognostic (2.34e-1)" "unprognostic (1.85e-1)" "unprognostic (3.45e-2)" "unprognostic (1.97e-1)" "unprognostic (2.04e-2)" "unprognostic (6.32e-2)" "unprognostic (1.46e-1)" "unprognostic (5.65e-2)" 0.3 0.8 1.7 1.7 1.5 0.0 0.2 0.9 1.9 0.1 5.6 0.4 0.5 0.2 1.0 0.2 0.3 0.4 1.6 1.6 1.4 3.9 0.5 0.4 0.6 1.6 2.3 0.1 0.3 6.0 0.3 0.2 1.8 0.1 0.5 0.0 0.2 0.4 0.0 0.1 0.5 0.3 1.8 0.6 0.4 9.2 2.2 1.1 1.9 0.0 0.5 0.5 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.4 0.0 0.0 0.3 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.1 1.9 0.7 0.2 0.0 0.7 0.5 2.9 0.0 0.7 0.0 0.0 0.8 0.0 0.3 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 1.7 1.5 0.9 1.9 1.6 1.4 1.6 2.3 1.8 1.8 2.2 3.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.8 0.4 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 6.3 0.0 0.4 0.0 0.0 6.0 0.0 4.4 0.0 0.0 4.0 8.1 0.6 0.0 3.2 0.0 41.2 9.0 0.0 0.0 3.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.6 0.0 0.3 0.1 0.1 0.4 0.0 0.1 KCTD20 "C6orf69, dJ108K11.3, MGC14254" ENSG00000112078 "Potassium channel tetramerization domain containing 20" Q7Z5Y7 6 36442767-36491143 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 126.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030092 Approved Approved "Nuclear speckles,Endoplasmic reticulum" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" "Endoplasmic reticulum" "Nuclear speckles" "HPA030092: AB_10601437" "unprognostic (2.17e-1)" "unprognostic (2.02e-1)" "unprognostic (5.20e-3)" "unprognostic (2.43e-2)" "unprognostic (1.00e-3)" "unprognostic (5.03e-3)" "prognostic unfavorable (8.32e-4)" "unprognostic (3.63e-1)" "unprognostic (1.80e-2)" "unprognostic (1.43e-1)" "unprognostic (1.22e-1)" "unprognostic (8.05e-2)" "prognostic unfavorable (8.02e-4)" "unprognostic (1.18e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (9.31e-4)" "unprognostic (2.94e-2)" 41.6 25.9 15.3 28.1 16.7 27.7 21.3 16.0 16.4 23.7 14.8 21.5 14.3 25.7 15.4 28.1 19.5 28.9 18.0 15.6 19.5 16.0 31.2 22.0 27.6 18.6 19.4 22.8 12.8 14.6 11.9 26.0 18.6 19.3 18.1 10.9 14.6 21.0 20.7 29.6 15.7 31.5 16.3 25.3 14.7 10.3 17.0 34.8 14.3 18.9 29.5 28.6 17.6 17.5 36.7 16.9 47.0 90.4 62.8 41.3 23.4 43.7 60.4 46.9 52.2 43.6 20.8 124.3 38.2 72.4 26.8 33.3 62.3 31.4 77.3 90.3 34.9 70.3 26.0 46.5 29.9 68.9 46.8 41.1 32.5 36.1 23.0 31.2 48.7 64.1 112.8 68.2 44.9 33.1 78.5 26.6 17.5 29.1 15.3 78.0 53.4 68.8 25.5 40.6 11.4 65.9 38.4 38.6 116.6 46.6 53.5 68.1 56.4 126.2 43.4 37.5 55.0 53.0 132.9 87.8 21.7 93.7 131.4 29.7 17.4 11.4 8.1 15.1 9.4 6.8 6.5 6.8 16.3 5.6 6.5 6.6 12.5 7.8 8.9 9.0 8.6 13.9 15.3 16.7 16.0 16.4 15.6 19.5 18.6 19.4 18.6 16.3 17.0 17.5 38.3 38.5 23.7 21.9 28.6 50.1 19.6 15.2 24.5 22.4 23.7 23.9 15.9 28.6 22.2 16.5 10.4 26.3 45.4 14.0 1.9 18.2 0.7 20.0 33.8 38.3 15.1 64.6 23.3 14.2 18.9 38.9 23.9 24.6 53.8 40.8 44.6 45.6 26.7 15.2 23.3 15.5 12.2 51.3 126.3 2.3 31.7 61.4 33.8 27.2 58.4 18.1 30.9 22.6 26.5 19.5 16.3 53.4 48.7 18.9 18.8 19.0 22.5 10.5 19.7 35.8 42.7 8.1 27.2 27.6 63.4 23.0 39.6 23.8 16.1 32.2 KDM6B "JMJD3, KIAA0346" ENSG00000132510 "Lysine demethylase 6B" O15054 17 7834217-7854796 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Inflammatory response" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 393.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 3.6;neutrophil: 8.9" "Lineage enriched" "Detected in single" 12 "granulocytes: 8.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037988 Supported Approved "Nuclear speckles" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 82: Adipose tissue - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 41: Macrophages - Immune response" "Nuclear speckles" "HPA037988: AB_10672502" "unprognostic (3.43e-1)" "unprognostic (3.43e-1)" "unprognostic (1.09e-1)" "unprognostic (2.13e-3)" "unprognostic (1.14e-1)" "unprognostic (1.59e-1)" "unprognostic (1.21e-1)" "unprognostic (2.43e-1)" "unprognostic (9.89e-2)" "unprognostic (8.00e-2)" "unprognostic (1.47e-3)" "unprognostic (1.42e-2)" "prognostic favorable (6.07e-4)" "unprognostic (5.73e-2)" "unprognostic (1.56e-1)" "prognostic unfavorable (3.37e-4)" "unprognostic (1.85e-1)" 33.6 13.3 3.1 20.0 2.4 35.5 12.6 12.5 22.9 12.2 3.4 15.4 14.3 14.0 3.4 13.6 17.1 15.6 17.7 3.2 4.5 14.6 15.2 27.4 8.0 4.8 3.2 29.7 17.1 7.9 21.8 6.8 3.3 14.5 4.1 6.2 12.0 6.2 12.4 16.4 17.5 5.5 1.4 20.7 17.7 16.1 5.0 16.4 15.9 8.2 4.6 19.8 12.4 6.2 4.9 7.0 12.5 19.0 4.6 3.4 16.2 3.8 5.4 2.7 2.8 9.3 3.6 11.4 4.5 3.0 3.9 12.2 5.8 5.1 1.6 4.7 4.5 5.3 6.7 6.2 13.0 7.2 15.6 5.3 8.0 6.1 5.1 7.2 4.8 11.8 8.8 4.8 1.2 7.7 10.6 6.5 6.4 4.9 3.9 11.9 2.9 3.2 5.1 7.7 6.6 21.4 4.8 11.5 10.3 7.3 6.4 8.9 2.3 4.0 7.1 7.0 5.5 5.6 1.2 3.9 5.3 4.2 8.1 3.6 0.6 1.1 0.3 0.4 0.3 0.3 0.2 0.1 0.3 0.5 0.3 0.4 8.9 0.1 0.2 0.7 0.1 0.4 3.1 2.4 12.5 22.9 3.2 4.5 4.8 3.2 3.3 1.4 5.0 6.2 135.5 25.6 33.6 6.2 158.8 214.4 122.2 30.8 156.0 45.2 113.7 70.9 10.8 42.9 32.4 7.3 31.3 15.1 127.6 47.8 1.9 28.0 29.2 88.2 67.1 80.5 79.9 8.4 9.0 25.1 15.9 85.4 73.4 181.6 178.6 44.8 34.2 22.7 23.4 38.7 10.9 62.5 18.3 50.4 393.1 10.7 16.4 219.2 56.9 4.7 25.6 13.2 9.2 5.5 1.9 58.4 49.1 13.9 70.7 99.6 53.9 9.8 20.5 17.1 19.7 181.2 83.0 20.1 19.3 138.1 188.0 52.0 104.1 22.0 46.2 86.6 KIAA0100 "BCOX, BCOX1, CT101, DKFZp686M0843, FMP27, MGC111488" ENSG00000007202 KIAA0100 Q14667 17 28614446-28645454 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042781 Uncertain Approved "Nuclear speckles,Cytosol" "Secreted to blood" No No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles, Cytosol" "HPA042781: AB_10797020" "unprognostic (1.91e-1)" "unprognostic (1.03e-2)" "unprognostic (3.47e-2)" "unprognostic (5.26e-3)" "unprognostic (2.43e-1)" "unprognostic (6.89e-2)" "prognostic unfavorable (3.47e-5)" "unprognostic (4.99e-2)" "unprognostic (3.04e-1)" "unprognostic (3.03e-3)" "unprognostic (2.40e-2)" "unprognostic (2.53e-1)" "unprognostic (4.24e-3)" "unprognostic (7.58e-2)" "unprognostic (5.84e-2)" "unprognostic (1.22e-1)" "unprognostic (6.67e-2)" 36.1 30.7 22.4 28.5 20.7 31.5 30.6 18.2 23.5 22.7 31.7 30.8 19.7 23.1 25.7 31.3 29.2 20.5 24.2 24.4 21.3 43.0 18.6 30.7 28.4 29.9 24.4 23.9 24.4 51.8 25.2 29.6 29.3 27.1 34.8 27.5 28.9 27.1 51.9 31.8 26.7 35.3 20.2 28.8 23.3 24.9 26.5 32.3 35.4 42.5 34.9 30.3 16.0 20.6 66.5 123.8 61.4 58.8 109.3 64.8 44.8 60.9 80.1 72.3 67.6 85.9 29.4 92.0 71.2 111.2 75.3 86.2 91.4 89.6 87.1 102.8 88.7 73.2 95.9 47.2 47.0 129.1 121.3 66.5 68.2 98.0 74.1 56.1 104.9 64.1 70.6 29.0 66.8 94.4 94.5 61.1 26.9 119.0 46.6 71.7 69.0 60.0 43.4 116.9 60.2 46.5 76.8 205.5 50.7 76.0 123.2 88.6 98.1 55.0 60.4 74.5 116.2 27.2 33.8 58.0 62.8 81.7 65.4 0.3 1.1 1.5 1.2 1.0 1.2 1.1 0.5 1.0 1.3 0.6 0.6 0.7 0.7 0.8 1.2 2.9 0.7 0.7 22.4 20.7 18.2 23.5 24.4 21.3 29.9 24.4 29.3 20.2 26.5 20.6 21.5 16.0 17.8 15.0 16.5 10.3 8.9 8.7 15.4 31.7 19.3 14.7 30.2 14.3 13.0 12.9 29.2 15.3 34.4 30.5 5.9 9.9 19.4 20.4 16.1 16.4 12.1 14.1 19.1 11.0 9.4 14.1 21.4 16.4 8.2 20.4 18.5 30.5 10.6 28.6 18.3 16.4 8.2 31.5 18.6 23.2 9.3 19.9 10.6 14.0 25.3 14.3 21.6 11.6 12.7 9.8 12.1 6.4 17.1 15.8 17.9 15.1 15.1 22.5 0.0 20.3 20.1 30.5 28.1 22.9 11.1 45.6 17.0 24.2 22.6 11.7 KIAA1328 ENSG00000150477 KIAA1328 Q86T90 18 36829106-37232172 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 75.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 230.8;Alveolar cells type 2: 228.3;Inhibitory neurons: 113.9;Oligodendrocyte precursor cells: 117.6;Oligodendrocytes: 178.0;Respiratory ciliated cells: 122.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040946 Approved Approved "Nuclear speckles,Vesicles,Lipid droplets" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 16: U-266 - Nucleosome" "Cluster 11: Alveolar cells - Smell perception" "Nuclear speckles" "Vesicles, Lipid droplets" "HPA040946: AB_10794998" "unprognostic (3.66e-2)" "unprognostic (5.37e-4)" "unprognostic (2.76e-2)" "unprognostic (1.55e-3)" "unprognostic (1.59e-1)" "unprognostic (1.18e-2)" "unprognostic (2.46e-2)" "unprognostic (1.51e-3)" "unprognostic (1.99e-1)" "unprognostic (5.05e-2)" "unprognostic (3.18e-3)" "unprognostic (4.85e-2)" "unprognostic (1.06e-4)" "unprognostic (1.77e-1)" "unprognostic (2.25e-2)" "unprognostic (3.36e-2)" "unprognostic (2.64e-3)" 6.9 7.1 24.6 7.7 33.8 22.0 5.7 54.3 62.5 5.0 10.1 6.2 9.0 9.5 9.0 6.6 6.1 7.2 6.6 27.2 13.9 7.2 7.0 7.3 7.5 5.5 1.5 13.7 5.3 5.1 2.8 8.3 12.5 7.6 5.5 37.9 9.4 3.9 11.0 13.6 9.4 5.5 0.6 8.3 9.0 16.8 12.6 4.0 7.0 4.1 4.6 4.6 3.6 75.8 26.2 7.4 11.2 13.5 3.8 5.8 10.5 10.7 4.0 5.1 3.4 12.9 16.4 18.1 32.8 4.1 8.6 11.7 4.2 4.7 6.4 15.3 5.0 22.9 24.6 9.3 3.6 16.0 11.9 5.4 5.8 5.6 5.0 5.5 4.4 10.9 18.1 40.7 5.0 23.0 10.6 10.6 25.0 9.6 11.4 14.0 11.9 12.8 4.2 22.2 11.7 13.5 12.8 15.9 6.7 20.4 23.3 8.3 13.8 22.4 29.5 13.3 11.2 32.2 43.8 14.4 11.0 11.3 15.4 23.8 6.7 9.9 8.2 5.0 9.8 7.4 7.2 7.0 3.2 11.4 9.3 7.5 13.2 7.4 8.0 5.5 9.4 4.0 24.6 33.8 54.3 62.5 27.2 13.9 5.5 1.5 12.5 0.6 12.6 75.8 10.9 230.8 228.3 85.5 13.3 5.7 7.9 7.0 6.8 36.1 6.5 7.1 6.0 7.2 106.8 5.5 20.9 8.8 6.5 1.7 5.9 7.6 51.9 6.8 10.5 18.2 3.0 5.5 83.8 5.8 7.8 23.9 5.1 6.9 107.9 13.5 9.7 3.0 6.6 16.8 113.9 3.2 2.0 4.4 4.6 13.0 9.3 18.3 7.2 94.6 5.0 10.1 19.6 117.6 178.0 6.3 3.7 7.9 8.0 3.6 4.4 4.4 122.7 30.9 0.0 14.3 11.0 45.3 19.6 6.6 7.0 3.8 20.6 11.5 4.5 5.0 KIF22 "Kid, KNSL4, OBP-1, OBP-2" ENSG00000079616 "Kinesin family member 22" Q14807 16 29790719-29805384 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA-binding, Motor protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 88.5;lymphoid tissue: 73.0" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 288.7;Hepatocytes: 565.5;Proximal tubular cells: 194.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048213, HPA075670" Enhanced Supported "Nuclear speckles" NA Yes "Cluster 44: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 14: REH - Unknown function" "Cluster 2: Hepatocytes - Metabolism" "Nuclear speckles" "HPA048213: AB_2680316, HPA075670: " "unprognostic (3.71e-2)" "prognostic favorable (3.87e-8)" "unprognostic (1.86e-1)" "unprognostic (2.21e-3)" "unprognostic (1.25e-1)" "unprognostic (6.06e-3)" "unprognostic (5.06e-3)" "unprognostic (2.70e-1)" "unprognostic (2.70e-1)" "unprognostic (4.73e-2)" "unprognostic (7.84e-2)" "unprognostic (2.10e-2)" "unprognostic (2.21e-2)" "unprognostic (3.67e-2)" "unprognostic (2.62e-1)" "unprognostic (3.94e-2)" "unprognostic (1.67e-1)" 9.2 7.0 9.5 19.7 9.9 88.5 13.4 8.1 10.4 10.5 6.9 22.6 16.6 8.2 8.6 22.3 12.3 6.4 10.8 9.5 8.9 11.2 8.3 8.5 34.1 8.4 8.3 8.2 7.3 33.8 9.2 15.7 8.3 24.9 20.6 8.9 10.5 12.0 8.4 32.8 16.9 8.0 8.9 18.6 11.8 28.3 9.4 73.0 26.0 11.0 34.7 10.1 13.3 9.3 89.3 103.9 120.6 87.6 8.0 11.9 104.8 65.8 52.1 123.1 113.9 97.9 103.3 130.6 60.4 34.4 61.2 90.0 118.9 67.5 57.4 84.8 100.4 72.4 115.1 119.0 2.7 79.1 76.0 6.7 17.7 68.5 51.3 17.1 67.2 144.7 109.4 104.1 65.5 186.5 173.1 196.1 101.8 65.7 59.6 237.9 110.6 122.4 44.9 45.0 99.8 65.4 48.5 94.7 33.1 39.4 84.8 105.2 29.8 63.8 66.6 57.7 72.6 96.6 105.3 141.4 41.9 129.0 83.3 58.7 14.1 39.5 49.7 21.1 37.3 30.4 50.0 53.1 14.7 27.3 40.0 38.4 6.2 31.5 18.3 9.6 56.5 40.5 9.5 9.9 8.1 10.4 9.5 8.9 8.4 8.3 8.3 8.9 9.4 9.3 13.9 32.1 115.4 5.5 23.0 30.8 25.8 56.7 52.9 27.5 56.5 56.4 288.7 57.2 38.5 69.9 25.0 81.7 20.1 44.2 62.6 16.6 9.9 29.5 18.9 29.2 41.4 85.2 4.8 50.1 85.4 50.1 25.0 31.1 43.6 29.5 49.2 565.5 46.3 6.7 6.1 39.5 34.6 47.7 40.4 8.5 15.5 36.7 35.6 4.7 38.6 69.8 29.9 4.0 5.3 17.3 44.0 12.8 49.9 26.1 18.0 194.0 29.7 20.5 13.1 23.7 34.2 50.9 61.6 41.4 27.6 76.9 34.2 12.2 42.3 22.5 KLF15 KKLF ENSG00000163884 "Kruppel like factor 15" Q9UIH9 3 126342635-126357408 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 92.5" "Cell type enhanced" "Detected in many" "Astrocytes: 22.9;Cardiomyocytes: 29.7;Distal tubular cells: 29.4;Hepatocytes: 66.9;Peritubular cells: 19.9;Proximal tubular cells: 22.1" "Cancer enhanced" "Detected in many" "liver cancer: 30.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 57.4;HHSteC: 34.8;RPMI-8226: 20.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003286, HPA028866" Uncertain Supported "Nucleoplasm,Nuclear speckles,Vesicles" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" "Nucleoplasm, Nuclear speckles" Vesicles "HPA003286: , HPA028866: AB_10600819" "unprognostic (3.77e-3)" "unprognostic (1.08e-1)" "unprognostic (1.99e-2)" "unprognostic (1.07e-2)" "unprognostic (2.72e-3)" "unprognostic (2.11e-1)" "unprognostic (4.63e-2)" "unprognostic (1.09e-2)" "unprognostic (2.91e-1)" "unprognostic (1.32e-1)" "unprognostic (3.58e-2)" "unprognostic (1.10e-1)" "prognostic favorable (3.27e-7)" "unprognostic (6.75e-2)" "unprognostic (7.65e-2)" "unprognostic (1.91e-2)" "unprognostic (5.58e-3)" 36.5 6.2 42.2 0.8 50.7 0.1 25.4 45.1 69.5 15.8 37.5 18.6 1.2 19.1 4.1 7.1 29.7 3.5 31.4 41.7 40.6 20.3 92.5 18.6 1.8 64.9 45.9 46.3 48.5 4.5 10.4 1.7 47.2 17.6 0.9 3.9 19.7 5.2 67.3 10.3 10.2 2.5 44.9 3.6 30.2 5.6 44.7 1.2 11.1 32.4 0.8 27.0 12.0 48.4 0.8 0.0 2.2 9.2 57.4 1.0 10.0 0.6 1.4 0.7 1.3 1.1 0.0 3.4 0.9 0.0 1.7 0.1 5.3 0.1 0.2 0.2 2.0 0.1 0.8 7.9 34.8 0.0 0.2 5.4 0.5 0.0 1.2 0.0 0.6 4.5 4.3 7.4 0.2 0.7 0.0 1.3 6.6 1.3 0.3 4.7 0.2 20.2 0.1 0.8 0.7 7.7 0.1 0.3 10.2 3.3 0.5 4.6 0.3 0.3 0.4 0.3 0.3 4.7 0.6 0.7 0.2 1.5 1.3 25.1 7.6 10.3 7.0 10.2 8.2 12.3 7.3 7.4 8.2 11.4 9.4 11.3 16.7 12.8 9.3 9.0 10.5 11.7 42.2 50.7 45.1 69.5 41.7 40.6 64.9 45.9 47.2 44.9 44.7 48.4 1.5 6.4 4.6 22.9 0.8 0.0 2.9 0.2 0.6 1.3 7.8 1.8 29.7 15.7 0.7 0.0 0.0 0.1 0.1 0.0 29.4 0.1 0.1 2.5 4.4 2.1 0.0 2.7 0.6 0.0 0.2 8.1 3.1 3.4 0.0 13.7 8.2 66.9 0.1 0.0 2.8 0.1 0.0 2.6 0.0 0.8 12.2 0.4 1.8 2.8 0.0 12.0 0.0 15.1 5.7 0.4 0.0 19.9 0.9 5.2 0.0 22.1 0.8 3.3 0.0 12.0 5.5 0.1 0.1 0.3 0.0 0.3 0.5 0.6 0.1 1.8 KLHDC7A FLJ38753 ENSG00000179023 "Kelch domain containing 7A" Q5VTJ3 1 18480930-18485974 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 8.4;kidney: 19.5" "Cell type enhanced" "Detected in some" "Cholangiocytes: 5.7;Collecting duct cells: 9.2;Endometrial ciliated cells: 4.4;Gastric mucus-secreting cells: 5.6;Hepatocytes: 7.6;Proximal tubular cells: 9.9;Respiratory ciliated cells: 5.0" "Cancer enhanced" "Detected in many" "renal cancer: 10.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 5.4;CAPAN-2: 10.4;EFO-21: 5.2;NTERA-2: 5.7;RPTEC TERT1: 11.5;RT4: 9.5;T-47d: 10.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA056616 Uncertain Approved "Nuclear speckles" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles" "HPA056616: AB_2683193" "unprognostic (4.63e-1)" "unprognostic (3.74e-2)" "unprognostic (2.18e-1)" "unprognostic (5.25e-2)" "unprognostic (1.68e-3)" "unprognostic (2.02e-1)" "unprognostic (1.31e-2)" "unprognostic (1.80e-3)" "unprognostic (2.94e-2)" "unprognostic (1.91e-1)" "unprognostic (9.01e-2)" "unprognostic (2.79e-1)" "prognostic favorable (7.81e-9)" "unprognostic (4.64e-3)" "unprognostic (1.37e-1)" "unprognostic (3.44e-1)" "prognostic favorable (1.88e-4)" 0.5 0.0 0.0 0.0 0.0 0.0 4.5 0.7 0.1 2.3 8.4 0.6 0.4 0.0 0.2 1.3 0.8 1.0 0.0 0.5 0.0 19.5 4.7 1.0 0.0 0.0 0.0 0.0 3.2 0.0 0.1 0.0 0.0 0.4 0.7 0.0 1.7 1.1 0.0 0.0 0.3 0.0 0.0 0.0 4.9 0.2 0.1 0.0 1.6 0.0 0.0 3.2 0.3 0.0 0.2 5.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 3.1 10.4 0.0 5.2 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 1.1 0.0 0.2 0.0 0.0 11.5 9.5 2.8 0.0 0.0 0.8 0.0 1.0 10.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.2 0.0 0.0 0.1 0.3 0.5 0.0 0.0 1.7 0.4 1.2 5.7 2.2 9.2 0.0 0.1 0.0 0.3 1.9 2.0 0.4 4.4 0.3 0.1 0.0 0.0 0.0 2.2 0.1 0.1 5.6 3.0 0.0 0.1 0.0 7.6 0.1 0.0 0.0 0.4 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.0 1.1 0.0 9.9 5.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.6 KTI12 "MGC20419, SBBI81, TOT4" ENSG00000198841 "KTI12 chromatin associated homolog" Q96EK9 1 52032103-52033810 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031203, HPA031204, HPA031205" Approved Approved "Nuclear speckles,Cytoplasmic bodies" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 43: THP-1 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" "Nuclear speckles, Cytoplasmic bodies" "HPA031203: AB_2732464, HPA031204: AB_10600110, HPA031205: AB_10611380" "unprognostic (6.14e-2)" "unprognostic (9.45e-2)" "unprognostic (1.19e-3)" "unprognostic (3.36e-3)" "unprognostic (4.18e-1)" "unprognostic (1.83e-2)" "prognostic unfavorable (1.02e-4)" "unprognostic (1.74e-1)" "unprognostic (2.94e-1)" "unprognostic (3.72e-2)" "unprognostic (4.06e-2)" "unprognostic (8.08e-3)" "unprognostic (6.59e-2)" "unprognostic (3.36e-3)" "unprognostic (2.39e-1)" "unprognostic (3.59e-2)" "unprognostic (1.64e-2)" 7.5 10.2 4.2 6.9 4.0 16.7 5.9 4.5 4.4 4.5 4.9 6.5 4.9 7.3 4.7 5.8 6.9 3.8 5.1 4.0 5.0 4.9 6.8 4.2 8.7 4.5 4.1 9.2 6.8 3.9 6.4 4.2 4.1 4.0 4.0 2.5 4.0 4.7 4.6 5.5 7.6 4.7 4.1 8.5 7.1 7.2 4.9 6.6 4.0 3.5 7.6 5.5 3.8 4.4 14.0 13.4 5.3 12.5 17.8 14.8 16.6 13.9 17.0 20.1 17.1 15.2 6.7 16.0 15.3 14.5 29.8 15.6 18.7 16.4 13.9 16.5 20.9 16.6 14.6 14.9 12.3 23.8 15.7 13.9 12.5 16.0 8.6 8.7 13.8 14.0 25.2 7.7 17.1 11.1 17.5 26.7 10.3 12.2 14.9 16.3 14.6 21.5 19.4 10.0 9.3 13.5 13.4 23.3 25.8 12.0 4.5 37.2 10.4 16.2 10.1 19.4 26.3 28.6 25.8 25.4 17.9 25.2 12.1 17.0 21.6 16.4 22.1 24.5 24.9 29.8 24.7 27.0 29.4 22.7 29.0 20.7 4.5 24.2 19.3 44.6 26.9 18.8 4.2 4.0 4.5 4.4 4.0 5.0 4.5 4.1 4.1 4.1 4.9 4.4 10.8 3.2 5.1 0.0 14.3 7.1 13.2 14.1 5.7 6.1 5.3 6.1 3.1 8.6 6.3 3.7 0.0 12.1 17.5 1.8 5.9 11.3 2.3 4.4 10.6 8.4 2.4 8.6 0.0 10.9 17.0 8.6 3.1 3.9 6.3 26.3 9.3 5.9 10.0 10.1 0.0 3.9 6.1 6.6 6.4 1.2 11.5 6.0 5.4 0.0 13.6 9.7 10.3 0.0 0.0 10.5 3.4 10.1 9.5 7.8 3.1 11.6 4.7 4.9 19.7 8.1 10.7 20.3 9.3 6.7 7.4 18.3 10.6 28.1 4.7 11.5 LHPP HDHD2B ENSG00000107902 "Phospholysine phosphohistidine inorganic pyrophosphate phosphatase" Q9H008 10 124461823-124617888 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 198.8;choroid plexus: 104.0" "Cell type enhanced" "Detected in many" "Early spermatids: 114.9;Late spermatids: 163.3;Proximal tubular cells: 93.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009163, HPA009269" Enhanced Supported "Nuclear speckles,Cytosol" NA NA 820000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 70: Brain - Nervous system development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles, Cytosol" "HPA009163: AB_1079250, HPA009269: AB_1079249" "unprognostic (3.46e-2)" "unprognostic (1.23e-2)" "unprognostic (4.78e-2)" "unprognostic (3.89e-1)" "unprognostic (2.14e-1)" "unprognostic (1.96e-1)" "unprognostic (5.77e-3)" "unprognostic (2.02e-2)" "unprognostic (3.58e-1)" "unprognostic (1.93e-1)" "unprognostic (6.42e-2)" "unprognostic (5.55e-2)" "unprognostic (1.79e-3)" "unprognostic (2.52e-1)" "unprognostic (2.10e-1)" "unprognostic (1.98e-1)" "unprognostic (1.64e-1)" 12.9 32.0 135.1 8.2 173.7 10.5 13.0 159.3 190.6 18.5 104.0 27.1 23.4 20.2 13.4 24.1 10.0 10.2 17.5 129.7 156.5 28.4 60.2 9.2 11.8 179.2 165.8 9.0 15.9 9.2 14.5 8.6 170.7 14.0 8.5 7.5 18.3 12.5 10.2 15.3 21.1 10.2 151.1 14.0 20.1 24.2 156.3 9.7 29.4 4.8 15.2 14.7 16.1 198.8 24.7 12.0 4.7 12.1 18.2 14.7 12.8 8.2 18.0 5.5 10.0 2.1 22.4 24.4 19.7 13.5 6.1 26.1 1.4 4.7 5.7 5.4 16.3 17.6 4.1 11.4 18.5 3.6 27.6 11.0 20.0 5.4 13.0 16.0 8.8 21.4 8.9 9.5 6.9 24.5 12.0 11.3 8.5 10.4 6.8 12.4 5.3 31.8 12.1 3.2 2.7 14.2 6.3 22.6 8.2 6.5 17.2 0.6 4.2 8.5 12.2 7.2 2.3 7.9 2.5 7.8 7.7 6.8 2.0 8.1 28.8 25.3 16.1 24.5 20.8 41.0 18.7 17.2 35.6 43.3 22.4 16.0 4.8 7.9 29.0 13.4 32.1 24.4 135.1 173.7 159.3 190.6 129.7 156.5 179.2 165.8 170.7 151.1 156.3 198.8 5.0 3.2 14.8 22.9 29.1 7.4 9.4 22.1 13.1 6.0 19.8 19.8 15.8 12.8 19.4 7.3 0.0 54.2 6.2 17.9 33.2 5.3 114.9 17.7 12.7 4.6 9.5 19.8 29.4 2.3 24.7 11.2 19.9 8.2 10.8 23.3 6.1 61.1 26.5 11.8 27.8 21.3 24.4 16.0 8.1 163.3 5.9 12.9 17.8 8.4 15.6 9.8 8.2 15.6 76.4 3.3 30.2 10.5 19.7 6.7 80.5 93.8 24.9 6.4 13.1 5.2 9.5 33.1 11.3 30.7 5.4 24.2 12.1 12.4 23.0 16.3 LHX4 Gsh4 ENSG00000121454 "LIM homeobox 4" Q969G2 1 180230264-180278984 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant, Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "retina: 15.4" "Group enriched" "Detected in some" 12 "Bipolar cells: 98.6;Cone photoreceptor cells: 52.1;Early spermatids: 43.0;Late spermatids: 73.9" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 1.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 4.5;BEWO: 10.5;HeLa: 4.9" "Region enhanced" "Detected in single" "pons and medulla: 1.3" "Region enhanced" "Detected in single" "spinal cord: 1.9" HPA055705 Approved "Nuclear speckles" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 28: BEWO - Transcription regulation" "Cluster 56: Bipolar cells - Visual perception" "Nuclear speckles" "HPA055705: AB_2682892" "unprognostic (2.83e-2)" "unprognostic (3.23e-2)" "unprognostic (1.94e-1)" "unprognostic (2.86e-2)" "unprognostic (9.38e-2)" "unprognostic (5.76e-5)" "unprognostic (9.39e-4)" "unprognostic (1.47e-1)" "unprognostic (2.39e-3)" "unprognostic (2.95e-1)" "unprognostic (3.77e-3)" "unprognostic (2.72e-3)" "unprognostic (4.07e-8)" "unprognostic (3.63e-1)" "unprognostic (1.43e-1)" "unprognostic (6.44e-3)" "unprognostic (7.83e-3)" 0.5 0.6 0.3 0.8 0.2 0.6 0.6 1.8 0.3 0.9 0.0 0.9 0.8 0.8 0.0 0.7 0.8 0.4 0.4 0.2 0.1 0.9 0.5 0.6 0.7 0.3 0.6 1.1 1.4 0.0 1.4 0.9 0.7 0.7 0.3 15.4 0.8 0.0 0.5 1.0 1.0 0.0 0.0 0.9 0.7 1.8 0.1 0.0 1.1 0.0 0.0 0.7 0.9 0.2 1.0 4.5 1.1 2.3 0.0 0.0 10.5 1.2 0.3 0.3 0.1 0.8 1.9 1.1 0.3 0.0 0.4 1.9 2.1 0.0 0.5 0.6 1.7 0.8 4.9 0.5 0.0 1.2 1.3 0.0 0.0 0.0 0.0 0.4 0.0 1.1 1.3 0.4 0.0 2.3 0.6 2.2 0.9 0.3 0.2 0.7 2.8 0.4 0.0 0.9 1.1 0.9 1.2 0.9 0.4 0.9 2.5 0.2 1.4 1.0 1.8 1.0 0.7 0.7 0.3 0.9 0.3 0.9 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 1.8 0.3 0.2 0.1 0.3 0.6 0.7 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.3 0.1 0.0 0.6 0.0 98.6 0.4 0.0 0.7 0.0 0.1 0.0 52.1 0.5 0.5 2.2 0.0 0.0 43.0 0.5 0.8 0.2 0.0 0.0 0.3 0.0 0.5 0.1 0.0 1.1 0.0 0.3 0.0 0.0 0.1 5.0 0.3 0.5 0.0 0.0 0.0 73.9 0.6 0.3 0.0 0.0 0.0 2.6 0.0 0.5 0.4 0.0 0.1 0.0 0.2 0.0 0.4 1.6 0.1 5.4 0.0 1.2 0.2 0.3 0.6 0.0 0.0 0.1 0.1 0.4 0.3 0.0 LIMK1 LIMK ENSG00000106683 "LIM domain kinase 1" P53667 7 74082933-74122525 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 77.9" "Cell type enhanced" "Detected in many" "Granulosa cells: 27.6;Horizontal cells: 35.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-87 MG: 136.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028516, HPA073571" Approved Supported "Nuclear speckles,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 70: Brain - Nervous system development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 4: Macrophages - Innate immune response" "Nuclear speckles, Cytosol" "HPA028516: AB_10601751, HPA073571: " "unprognostic (1.45e-2)" "unprognostic (2.75e-1)" "prognostic unfavorable (4.95e-5)" "unprognostic (2.77e-2)" "unprognostic (1.40e-3)" "unprognostic (3.35e-2)" "prognostic unfavorable (7.79e-6)" "unprognostic (1.90e-2)" "unprognostic (2.16e-1)" "unprognostic (1.18e-1)" "unprognostic (3.32e-2)" "unprognostic (3.16e-2)" "prognostic unfavorable (6.63e-8)" "unprognostic (4.14e-2)" "unprognostic (7.00e-2)" "unprognostic (3.84e-2)" "unprognostic (5.79e-2)" 11.1 10.5 31.1 18.7 32.7 6.8 9.4 28.3 77.9 21.4 0.2 8.9 6.6 13.1 3.5 11.3 7.3 10.1 9.4 35.0 43.8 10.8 4.6 13.2 23.5 75.5 40.0 13.2 11.4 5.8 13.9 7.3 73.0 12.3 4.1 4.0 17.9 8.2 23.7 11.4 12.1 7.1 31.8 22.3 9.2 15.6 59.1 8.1 11.2 7.8 18.2 13.1 14.7 38.3 47.4 37.2 27.2 45.4 35.1 47.0 20.0 28.8 27.3 22.6 25.4 21.3 45.6 30.2 12.7 35.5 76.9 28.1 10.1 17.8 8.6 53.7 18.6 23.2 13.1 24.6 40.5 17.2 81.4 46.8 15.6 18.5 9.6 68.3 34.4 20.9 15.1 9.0 28.8 41.4 14.8 31.4 52.1 16.6 23.7 21.1 43.3 18.2 26.5 10.1 10.7 25.2 18.6 43.7 23.5 29.7 13.9 15.4 41.1 36.0 33.7 94.5 47.7 10.2 12.5 54.9 136.5 12.4 25.2 0.1 6.1 3.5 1.8 6.0 1.4 3.4 0.4 1.2 7.0 1.7 0.1 0.5 0.5 5.8 3.8 0.7 0.3 3.3 31.1 32.7 28.3 77.9 35.0 43.8 75.5 40.0 73.0 31.8 59.1 38.3 2.9 3.2 2.7 7.5 14.4 2.9 5.2 6.6 1.8 6.6 7.7 6.9 3.4 7.2 3.8 1.8 2.1 2.5 11.9 2.9 0.0 6.6 1.2 2.7 9.7 4.1 2.4 0.4 15.4 6.5 6.3 9.2 3.1 5.1 5.7 27.6 3.3 2.1 25.0 35.3 20.8 2.7 0.0 13.5 10.8 2.2 7.2 15.6 3.6 6.5 14.9 3.5 22.6 6.6 2.4 13.5 2.3 6.0 10.0 9.0 0.3 2.8 3.1 3.3 0.0 5.3 4.5 3.4 11.5 1.8 3.1 3.7 11.1 6.9 2.4 7.2 LIN52 C14orf46 ENSG00000205659 "Lin-52 DREAM MuvB core complex component" Q52LA3 14 74084796-74201235 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 47.5;Inhibitory neurons: 65.4;Oligodendrocyte precursor cells: 60.3;Oligodendrocytes: 60.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000900, HPA001777" Uncertain Approved "Nuclear speckles" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear speckles" "HPA000900: AB_2135058, HPA001777: AB_2666431" "unprognostic (2.34e-2)" "unprognostic (6.51e-3)" "unprognostic (1.86e-1)" "unprognostic (1.94e-1)" "unprognostic (7.90e-3)" "prognostic favorable (6.60e-4)" "prognostic unfavorable (6.08e-5)" "unprognostic (2.48e-3)" "unprognostic (9.34e-2)" "unprognostic (8.65e-2)" "unprognostic (1.39e-3)" "unprognostic (3.18e-1)" "unprognostic (1.74e-3)" "unprognostic (1.20e-2)" "unprognostic (8.28e-2)" "unprognostic (2.43e-2)" "unprognostic (1.04e-1)" 8.0 7.8 8.4 5.4 8.4 3.5 6.3 8.8 10.1 5.8 7.8 4.5 6.5 7.0 5.7 4.9 5.5 4.9 10.2 8.3 10.0 19.3 6.6 5.0 6.1 9.2 8.9 8.5 3.4 6.8 5.7 5.0 9.3 6.4 5.7 10.7 3.9 5.6 5.6 3.8 5.8 6.8 7.9 5.1 4.3 7.5 8.9 10.7 5.1 10.0 6.3 5.8 3.9 8.5 10.5 7.7 26.8 12.8 15.5 6.6 10.5 17.5 16.7 23.0 25.7 14.0 9.6 5.9 5.3 8.6 9.2 9.2 20.4 6.9 35.1 49.1 8.1 9.1 8.9 20.0 16.6 9.4 12.7 8.2 7.7 12.2 15.9 6.3 11.0 18.6 9.7 27.8 11.4 13.4 14.9 12.3 7.7 13.8 12.3 19.0 25.1 9.6 6.0 6.2 19.0 15.5 16.4 12.0 13.7 9.9 16.3 13.5 6.3 10.8 20.3 11.5 14.8 18.2 41.8 13.2 12.5 10.7 18.4 6.2 6.4 20.6 10.7 6.6 16.6 8.7 9.3 10.7 8.6 9.4 13.7 12.5 3.2 11.4 4.8 7.9 13.9 10.1 8.4 8.4 8.8 10.1 8.3 10.0 9.2 8.9 9.3 7.9 8.9 8.5 5.6 9.6 9.0 39.8 10.4 4.8 3.2 3.2 11.4 8.8 7.6 5.3 10.0 10.0 6.6 5.5 8.4 6.3 8.8 3.5 7.9 3.1 0.8 5.9 6.6 7.4 3.0 16.4 47.5 2.4 5.2 8.1 6.1 6.7 2.5 9.0 6.4 12.2 6.3 16.8 65.4 6.0 4.1 4.3 3.7 1.6 5.3 4.5 0.0 26.2 6.6 10.8 10.3 60.3 60.4 2.4 5.0 9.8 27.3 3.3 10.9 22.4 6.2 7.5 6.6 8.1 6.4 16.3 10.4 10.3 5.5 8.8 8.2 3.7 4.7 1.4 LINC00634 ENSG00000205704 "Long intergenic non-protein coding RNA 634" 22 41952174-41958933 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 9 "brain: 33.2;choroid plexus: 10.7" "Group enriched" "Detected in some" 35 "Astrocytes: 5.2;Excitatory neurons: 4.0;Inhibitory neurons: 3.6;Oligodendrocyte precursor cells: 3.5;Oligodendrocytes: 1.6" "Cancer enriched" "Detected in single" 13 "glioma: 5.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "REH: 2.9;SCLC-21H: 2.7" HPA029815 Approved "Nuclear speckles,Cytosol" NA NA "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 64: Astrocytes - Nervous system maintenance" "Nuclear speckles" Cytosol "HPA029815: AB_10601803" "unprognostic (1.42e-1)" "unprognostic (8.80e-4)" "unprognostic (3.93e-4)" "unprognostic (9.78e-2)" "unprognostic (2.94e-2)" "unprognostic (1.53e-1)" "unprognostic (1.72e-4)" "unprognostic (6.59e-2)" "unprognostic (1.41e-1)" "unprognostic (1.10e-2)" "unprognostic (1.17e-2)" "unprognostic (6.00e-2)" "unprognostic (1.11e-6)" "unprognostic (5.40e-2)" "unprognostic (5.76e-2)" "unprognostic (2.99e-1)" "unprognostic (3.17e-1)" 0.0 2.1 27.4 0.0 25.9 0.1 0.0 16.3 33.2 0.0 10.7 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 30.2 22.6 0.0 0.0 0.0 0.0 19.0 23.6 0.0 0.0 0.0 0.0 17.9 0.1 0.0 2.4 0.0 0.3 0.0 0.0 0.0 0.0 15.6 0.0 0.2 1.0 30.1 0.0 0.0 0.0 0.1 0.0 21.9 0.3 0.0 1.3 1.3 0.0 0.7 0.8 0.0 0.0 0.2 0.3 0.4 1.0 2.4 0.1 0.0 0.9 0.2 0.0 0.0 0.0 0.9 2.1 0.1 0.2 0.2 0.1 0.0 0.2 0.0 0.0 0.6 0.6 0.0 0.0 2.5 0.1 1.5 0.0 0.6 1.0 1.4 0.3 0.3 2.0 2.9 0.5 0.1 0.0 0.1 2.7 1.8 0.1 0.1 0.3 0.2 0.3 0.0 0.0 0.2 1.1 0.0 0.3 0.8 1.7 2.4 0.0 0.7 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.4 25.9 16.3 33.2 30.2 22.6 19.0 23.6 17.9 15.6 30.1 21.9 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LMNA "CMD1A, HGPS, LGMD1B, LMN1, LMNL1, MADA, PRO1" ENSG00000160789 "Lamin A/C" P02545 1 156082573-156140081 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Cardiomyopathy, Charcot-Marie-Tooth disease, Congenital muscular dystrophy, Disease variant, Emery-Dreifuss muscular dystrophy, Limb-girdle muscular dystrophy, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 1533.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 85.1;T-reg: 83.2" "Group enriched" "Detected in all" 8 "dendritic cells: 85.1;granulocytes: 23.9;T-cells: 83.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004022, HPA006523, HPA006660" Supported Supported "Nuclear speckles" NA NA 5700000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 17: WM-115 - Nervous system development" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles" "CAB004022: AB_2136278, HPA006523: , HPA006660: AB_1079231" "unprognostic (2.22e-2)" "unprognostic (1.89e-1)" "unprognostic (1.04e-2)" "unprognostic (5.75e-2)" "unprognostic (7.43e-3)" "unprognostic (1.47e-1)" "unprognostic (5.23e-3)" "unprognostic (3.27e-2)" "unprognostic (8.33e-2)" "unprognostic (5.90e-2)" "unprognostic (5.10e-2)" "unprognostic (6.34e-2)" "unprognostic (1.41e-2)" "unprognostic (1.24e-1)" "unprognostic (2.89e-1)" "unprognostic (3.08e-2)" "unprognostic (1.44e-2)" 280.2 174.8 17.6 64.9 27.1 58.1 231.5 24.1 20.6 221.7 33.0 183.3 72.8 271.4 14.5 256.2 173.8 92.1 221.7 15.8 23.1 120.9 93.2 188.5 18.2 30.3 25.2 178.2 81.8 21.3 76.9 53.0 26.1 125.3 38.2 4.7 176.1 42.8 190.0 364.3 136.8 78.8 21.0 84.1 160.6 61.9 30.9 15.3 147.4 23.8 22.9 168.7 217.6 41.8 518.8 269.7 26.2 72.4 119.5 238.7 169.4 607.3 379.6 221.3 146.8 68.3 311.9 2.8 338.7 417.9 94.6 515.4 31.4 227.8 70.3 188.6 50.8 175.4 168.4 130.8 124.0 25.7 412.9 133.0 92.0 154.8 134.7 120.2 207.5 0.7 82.8 21.9 205.8 193.1 1.0 67.8 32.1 202.9 706.0 1.6 195.9 137.7 128.9 105.6 33.8 114.9 414.3 154.2 427.4 56.2 230.1 74.2 727.9 241.6 233.0 389.1 393.3 39.5 10.5 4.9 449.2 24.8 760.4 23.9 8.3 0.4 2.8 2.1 2.5 2.4 17.8 7.3 85.1 0.2 0.2 0.7 2.1 3.7 0.2 0.3 83.2 14.6 17.6 27.1 24.1 20.6 15.8 23.1 30.3 25.2 26.1 21.0 30.9 41.8 353.5 262.8 350.0 16.0 179.1 610.5 1235.3 446.2 531.6 7.2 542.5 374.9 94.1 191.6 320.3 161.8 47.9 478.8 239.8 614.1 109.5 429.3 38.6 215.4 209.4 386.0 431.5 70.4 9.9 360.2 387.8 622.1 505.1 270.5 1181.8 145.5 277.7 103.1 343.0 13.5 15.1 601.2 177.0 60.6 1533.4 45.4 288.6 409.0 859.2 10.3 20.4 37.2 3.1 17.1 20.1 513.0 384.1 287.3 331.3 340.6 262.6 125.0 170.5 17.8 203.8 1028.4 766.8 107.4 42.2 404.1 602.4 680.9 472.3 111.6 513.8 942.6 LMTK2 "AATYK2, BREK, cprk, KIAA1079, KPI-2, KPI2, LMR2, PPP1R100" ENSG00000164715 "Lemur tyrosine kinase 2" Q8IWU2 7 98106862-98209638 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 50.7;Excitatory neurons: 114.9;Inhibitory neurons: 69.0;Oligodendrocyte precursor cells: 52.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 25.2" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010657, HPA041836" Uncertain Approved "Nuclear speckles,Plasma membrane,Centriolar satellite,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear speckles, Centriolar satellite" "Plasma membrane, Cytosol" "HPA010657: AB_1079259, HPA041836: AB_2677698" "unprognostic (7.36e-2)" "unprognostic (3.16e-1)" "unprognostic (1.59e-1)" "unprognostic (2.60e-3)" "unprognostic (2.47e-2)" "unprognostic (2.45e-1)" "unprognostic (2.35e-2)" "unprognostic (1.23e-1)" "unprognostic (4.96e-1)" "prognostic unfavorable (8.03e-4)" "unprognostic (1.23e-1)" "unprognostic (4.65e-1)" "prognostic favorable (1.12e-7)" "unprognostic (1.88e-1)" "unprognostic (3.92e-1)" "unprognostic (2.16e-2)" "unprognostic (6.38e-3)" 3.5 7.0 4.2 3.9 6.2 13.8 3.6 0.0 25.2 4.9 0.0 9.7 8.8 3.9 3.9 9.5 4.1 4.2 12.4 6.0 0.0 6.6 6.2 6.6 3.6 2.1 0.5 5.0 14.8 10.7 7.0 3.1 1.8 5.1 8.0 8.2 7.9 4.0 11.1 9.0 9.8 3.7 0.0 4.6 6.5 5.2 1.2 4.9 5.8 7.0 4.8 5.8 6.2 8.7 12.5 14.5 11.0 11.4 5.8 4.6 10.2 5.1 5.5 4.9 5.9 11.5 11.1 6.5 14.3 6.5 18.6 13.4 12.8 7.8 7.6 9.4 9.0 4.4 13.0 11.6 7.0 8.0 7.6 3.2 10.5 10.1 13.6 4.9 7.4 7.4 11.8 13.4 4.5 16.9 8.5 4.8 13.4 17.1 7.0 9.2 7.5 13.0 8.2 21.7 7.8 15.7 10.2 18.4 7.4 11.0 5.1 3.2 9.2 10.2 16.6 20.5 11.7 5.9 11.2 12.8 6.8 6.2 12.3 0.5 0.1 0.1 0.2 0.0 0.1 0.1 0.2 0.2 0.1 0.2 0.3 0.4 1.4 0.1 0.3 0.2 0.2 0.1 4.2 6.2 0.0 25.2 6.0 0.0 2.1 0.5 1.8 0.0 1.2 8.7 6.0 28.9 17.0 28.7 7.8 9.7 4.3 6.2 14.8 14.2 5.5 3.9 22.4 15.7 11.8 1.8 14.6 2.8 7.5 50.7 1.9 6.1 1.1 13.2 7.6 5.7 12.0 8.4 114.9 9.1 1.9 5.4 21.4 26.4 2.5 5.3 2.5 8.4 2.2 6.7 69.0 14.7 4.1 1.6 2.3 2.0 1.8 3.2 1.8 16.9 2.8 6.1 7.2 52.3 29.6 10.3 23.8 4.5 12.9 8.8 14.0 3.0 15.8 10.6 0.0 8.6 5.7 6.9 6.3 15.5 10.9 3.0 8.6 2.7 14.7 20.5 LNP1 NP3 ENSG00000206535 "Leukemia NUP98 fusion partner 1" A1A4G5 3 100401532-100456319 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "retina: 46.1;testis: 29.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 50.1;Early spermatids: 147.6;Horizontal cells: 257.4;Spermatocytes: 91.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.4" "Lineage enriched" "Detected in single" 4 "T-cells: 1.4" "Cell line enhanced" "Detected in many" "PC-3: 18.7;U-266/84: 17.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "amygdala: 6.8;cerebral cortex: 8.7;hippocampal formation: 7.3;olfactory bulb: 5.0" HPA047926 Approved "Nuclear speckles,Vesicles,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 16: U-266 - Nucleosome" "Cluster 62: Horizontal cells - Visual perception" Vesicles "Nuclear speckles, Cytosol" "HPA047926: " "unprognostic (1.78e-1)" "unprognostic (3.70e-2)" "unprognostic (8.33e-3)" "unprognostic (4.40e-3)" "unprognostic (6.33e-3)" "unprognostic (1.17e-1)" "unprognostic (1.34e-1)" "unprognostic (1.66e-3)" "unprognostic (1.81e-1)" "unprognostic (1.75e-2)" "unprognostic (1.58e-2)" "unprognostic (1.74e-2)" "unprognostic (8.28e-3)" "unprognostic (1.43e-1)" "unprognostic (7.98e-2)" "unprognostic (2.11e-1)" "unprognostic (6.08e-2)" 2.2 1.9 5.1 0.8 5.9 0.1 1.9 5.3 6.1 2.6 3.0 2.5 0.6 3.1 6.7 1.3 3.0 2.0 8.5 5.2 6.0 4.3 7.7 3.1 0.9 5.2 5.1 3.9 3.3 1.7 6.1 2.7 6.4 1.9 1.5 46.1 2.0 2.3 2.9 0.7 1.2 2.7 4.6 1.2 1.5 29.0 4.7 1.3 3.6 2.1 1.1 3.1 1.7 5.3 3.2 1.7 9.9 0.9 4.1 2.9 0.7 2.0 6.3 2.7 2.8 0.9 0.9 2.4 0.9 1.9 2.8 2.1 1.8 3.2 2.9 2.6 2.1 7.1 0.5 4.0 1.8 5.4 0.8 3.5 0.8 1.2 5.0 2.5 0.3 1.0 2.7 11.6 2.1 2.7 6.2 4.3 7.6 2.1 18.7 4.6 5.4 6.1 1.9 0.4 9.5 4.9 1.6 2.7 4.5 2.3 0.6 0.6 0.7 1.0 10.4 1.0 2.2 14.9 17.3 9.5 3.3 3.3 2.1 0.0 0.0 0.0 0.4 0.0 0.9 0.3 0.3 0.2 0.2 0.1 0.4 0.4 0.0 0.1 0.0 0.0 1.4 0.1 5.1 5.9 5.3 6.1 5.2 6.0 5.2 5.1 6.4 4.6 4.7 5.3 0.9 0.0 0.5 4.2 1.8 1.0 1.3 0.7 2.2 42.2 2.2 1.9 10.5 0.0 1.5 1.8 50.1 1.5 0.3 0.6 7.9 0.8 147.6 0.9 2.3 1.2 2.4 6.1 6.9 1.0 1.9 3.2 3.1 0.7 0.0 1.2 0.0 1.7 0.6 257.4 11.3 1.6 0.0 0.3 0.3 34.2 3.4 0.3 21.4 0.0 0.7 17.1 1.0 7.5 3.7 0.6 0.5 1.2 7.5 0.8 1.1 6.0 3.3 44.3 0.0 1.9 4.6 91.8 3.3 0.6 0.6 0.4 0.7 0.7 0.8 0.5 LPAR1 "edg-2, EDG2, Gpcr26, GPR26, LPA1, Mrec1.3, rec.1.3, vzg-1" ENSG00000198121 "Lysophosphatidic acid receptor 1" Q92633 9 110873263-111038458 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 358.4;choroid plexus: 122.2" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 626.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 9.1;eosinophil: 19.0" "Group enriched" "Detected in many" 6 "granulocytes: 19.0;monocytes: 9.1" "Cell line enhanced" "Detected in many" "ASC diff: 582.0;ASC TERT1: 337.0;BJ hTERT+: 426.7;HSkMC: 246.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050667 Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nuclear speckles" "Plasma membrane" "HPA050667: " "unprognostic (1.35e-1)" "unprognostic (1.41e-1)" "unprognostic (4.79e-2)" "unprognostic (6.08e-3)" "unprognostic (1.03e-1)" "unprognostic (1.16e-1)" "unprognostic (2.17e-2)" "unprognostic (2.10e-1)" "unprognostic (1.40e-2)" "unprognostic (4.13e-2)" "unprognostic (1.02e-1)" "unprognostic (4.29e-3)" "unprognostic (2.12e-2)" "unprognostic (5.42e-3)" "unprognostic (2.78e-2)" "unprognostic (9.97e-3)" "unprognostic (1.65e-1)" 30.5 13.3 251.0 18.8 315.0 0.2 25.9 208.8 318.6 57.7 122.2 24.5 13.9 17.0 17.1 15.2 15.8 14.1 24.1 199.5 201.3 9.6 2.6 16.3 17.6 299.6 277.5 12.1 6.6 2.2 5.0 38.8 249.2 21.0 18.3 0.8 16.7 23.6 6.6 20.1 18.3 20.5 224.0 14.8 11.8 6.9 266.2 6.8 16.5 17.5 17.2 27.6 31.7 358.4 11.7 22.2 30.4 0.1 582.0 337.0 0.0 151.6 426.7 104.1 46.8 3.0 1.8 0.0 0.1 157.7 18.6 45.5 0.4 118.5 85.0 0.0 4.1 0.0 1.1 0.0 157.1 0.1 0.2 246.6 6.8 51.4 96.9 62.3 1.8 0.2 0.0 0.2 80.8 0.1 0.0 0.1 5.9 0.0 121.6 0.1 22.4 0.0 23.5 20.6 0.9 7.2 3.1 0.0 0.0 6.2 10.4 0.5 0.1 48.9 1.3 35.3 0.1 1.5 0.0 0.0 7.4 0.0 54.9 1.5 9.1 19.0 0.0 3.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 1.9 2.1 1.3 0.2 0.0 2.1 251.0 315.0 208.8 318.6 199.5 201.3 299.6 277.5 249.2 224.0 266.2 358.4 1.9 0.0 1.1 6.2 0.2 13.0 15.5 8.5 4.0 0.0 3.4 6.0 1.4 1.5 9.1 0.0 0.0 0.5 0.3 6.6 1.9 1.8 1.4 3.6 40.4 1.9 0.0 0.0 1.0 2.9 0.4 61.4 6.1 8.7 0.0 0.0 2.5 0.0 3.3 0.0 15.6 3.7 4.1 4.1 15.1 2.7 38.8 3.6 14.2 141.5 12.0 1.0 1.0 1.0 626.8 2.0 2.9 70.7 0.7 12.7 4.5 0.2 3.0 0.2 0.0 13.3 6.3 0.3 2.4 15.2 9.2 0.8 1.2 0.2 4.2 6.7 LPXN LDPL ENSG00000110031 Leupaxin O60711 11 58526871-58578220 "Predicted intracellular proteins" "Cell adhesion, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 118.5" "Cell type enhanced" "Detected in many" "B-cells: 75.9;dendritic cells: 80.7;Langerhans cells: 154.6;Macrophages: 81.7;Plasma cells: 82.2;T-cells: 90.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 200.7;HMC-1: 329.3;Karpas-707: 285.0;U-2197: 199.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043741, CAB046478, HPA061441" Enhanced Supported "Nuclear speckles,Focal adhesion sites,Cytosol" No No "Cluster 13: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "Focal adhesion sites" "Nuclear speckles, Cytosol" "CAB046478: AB_10603113, HPA043741: AB_2678647, HPA061441: AB_2684518" "unprognostic (1.61e-3)" "unprognostic (6.91e-2)" "unprognostic (6.54e-2)" "prognostic favorable (8.81e-4)" "unprognostic (5.16e-2)" "unprognostic (2.07e-3)" "unprognostic (2.16e-2)" "unprognostic (8.87e-3)" "unprognostic (5.18e-2)" "unprognostic (3.96e-2)" "unprognostic (2.39e-2)" "unprognostic (3.05e-1)" "unprognostic (3.60e-3)" "unprognostic (1.91e-1)" "unprognostic (5.25e-2)" "unprognostic (2.55e-1)" "unprognostic (2.41e-3)" 10.4 8.3 7.5 48.3 8.2 10.2 10.2 7.8 11.8 7.9 4.5 14.5 10.9 7.4 11.9 5.2 7.6 15.1 5.3 7.1 7.8 10.6 14.0 33.5 87.1 9.1 8.8 9.5 8.6 6.5 7.2 5.2 10.2 9.4 19.6 7.0 11.0 7.1 3.8 5.9 26.2 9.7 8.6 44.1 13.0 10.2 10.0 103.3 10.2 5.1 118.5 32.4 6.0 10.9 1.7 2.1 2.0 3.9 7.4 9.3 1.4 50.5 200.7 12.4 22.0 0.4 5.1 149.8 2.0 61.9 9.2 2.0 1.7 137.7 51.4 65.4 0.9 6.8 1.3 1.0 12.8 41.1 329.3 7.2 3.2 170.8 22.0 12.0 80.9 90.0 1.9 285.0 101.5 1.1 144.8 51.6 1.6 2.3 45.8 2.1 2.5 129.2 8.3 71.2 1.0 1.6 2.2 3.2 20.1 2.8 2.7 11.7 79.8 30.8 9.5 199.5 45.9 18.4 18.9 146.5 71.6 36.8 71.6 6.3 74.3 12.2 101.3 41.8 148.9 71.9 102.9 117.6 137.5 46.2 79.6 95.9 14.1 79.2 22.2 124.4 152.1 98.8 7.5 8.2 7.8 11.8 7.1 7.8 9.1 8.8 10.2 8.6 10.0 10.9 4.1 0.0 6.7 22.9 75.9 9.7 6.6 7.2 3.4 4.1 4.0 4.7 2.3 4.3 2.8 0.0 4.2 2.8 80.7 4.2 3.9 2.5 23.0 2.8 1.9 5.9 6.1 13.3 18.2 5.6 1.3 6.6 13.3 2.3 51.5 5.4 2.5 7.6 44.0 1.7 19.8 3.1 6.1 63.7 154.6 8.7 1.8 81.7 19.6 30.0 52.9 2.8 49.4 11.6 27.3 4.1 5.2 3.8 82.2 3.6 6.9 5.7 4.3 4.4 6.6 3.6 3.8 9.2 4.2 2.6 9.7 2.5 90.3 2.9 5.2 27.6 LUC7L3 "CRA, CREAP-1, CROP, FLJ11063, hLuc7A, LUC7A, OA48-18" ENSG00000108848 "LUC7 like 3 pre-mRNA splicing factor" O95232 17 50719565-50756219 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018475, HPA018484, HPA020017" Enhanced Enhanced "Nuclear speckles" NA NA 15000 "Cluster 37: B-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "HPA018475: AB_1847247, HPA018484: AB_1847248, HPA020017: AB_1847249" "unprognostic (3.90e-1)" "unprognostic (4.71e-2)" "unprognostic (2.15e-1)" "unprognostic (1.05e-1)" "unprognostic (8.47e-2)" "unprognostic (2.99e-3)" "prognostic unfavorable (1.05e-5)" "unprognostic (1.39e-2)" "unprognostic (1.24e-2)" "unprognostic (1.18e-2)" "prognostic favorable (6.07e-4)" "unprognostic (1.16e-3)" "prognostic unfavorable (8.41e-7)" "unprognostic (7.23e-2)" "unprognostic (1.49e-1)" "unprognostic (1.67e-1)" "prognostic favorable (5.35e-5)" 86.8 108.2 128.2 91.1 134.2 75.9 96.4 165.6 193.2 172.2 131.4 163.3 99.4 144.8 88.1 98.3 157.5 63.8 102.8 126.1 138.7 112.7 90.8 119.0 132.4 131.3 128.4 223.5 111.6 63.6 172.0 78.5 132.5 141.3 75.1 175.8 94.8 73.4 151.9 105.3 131.2 65.8 124.6 133.6 113.7 73.7 133.5 84.1 144.0 43.2 88.4 130.1 136.5 148.4 176.7 114.3 222.8 143.1 91.5 87.9 105.5 162.8 63.0 77.0 92.1 214.5 132.4 212.5 171.1 65.2 87.5 148.8 149.4 67.5 132.2 226.6 242.5 251.5 445.3 174.9 50.5 223.4 136.0 84.2 94.5 84.2 48.7 193.7 79.9 164.9 202.9 188.0 99.1 99.1 221.4 218.0 146.2 125.3 83.4 238.2 208.4 224.0 105.5 109.8 158.1 163.2 96.8 121.5 179.3 192.6 196.3 164.9 113.7 170.9 146.3 72.8 171.5 167.8 191.7 265.1 108.1 152.5 123.9 49.1 32.3 32.6 32.0 24.0 28.2 67.3 35.7 27.6 21.2 55.4 37.1 30.5 47.8 23.3 19.8 64.7 29.6 12.1 128.2 134.2 165.6 193.2 126.1 138.7 131.3 128.4 132.5 124.6 133.5 148.4 129.7 150.6 194.2 231.8 177.8 216.2 200.9 99.4 200.3 512.3 121.1 129.5 111.5 70.1 148.3 93.8 229.4 104.8 237.1 130.8 74.3 102.6 18.9 111.1 171.8 151.9 207.8 191.2 121.5 85.3 108.5 149.8 99.4 144.8 148.0 364.8 94.2 83.1 76.4 380.2 145.9 151.8 81.4 87.4 122.5 48.4 394.5 105.1 96.0 107.7 184.2 207.8 197.8 181.5 239.1 86.5 158.0 355.0 134.5 151.2 157.8 56.2 130.1 402.2 236.7 204.5 172.3 122.2 159.3 135.7 177.0 99.9 162.8 253.1 141.7 191.7 MAGEA4 "CT1.4, MAGE-41, MAGE-X2, MAGE4, MAGE4A, MAGE4B, MGC21336" ENSG00000147381 "MAGE family member A4" P43358 X 151912509-151925170 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Tumor antigen" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 23.6" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 20.2;Spermatocytes: 48.7;Spermatogonia: 179.8;Syncytiotrophoblasts: 33.0" "Cancer enhanced" "Detected in many" "lung cancer: 19.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 440.0;AN3-CA: 263.1;HMC-1: 496.1;U-266/84: 836.2" "HPA021942, CAB040535" Enhanced Approved "Nuclear speckles,Cytosol" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nuclear speckles" Cytosol "CAB040535: , HPA021942: AB_1853490" "unprognostic (7.90e-3)" "unprognostic (6.66e-3)" "unprognostic (5.39e-1)" "unprognostic (1.36e-1)" "unprognostic (5.81e-2)" "unprognostic (2.94e-2)" "unprognostic (4.10e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 23.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 440.0 0.0 0.0 263.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.5 0.0 0.1 0.6 0.0 0.0 0.0 0.8 0.0 0.0 0.3 0.1 0.0 0.0 496.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.8 0.0 0.0 0.4 0.0 0.2 0.0 0.3 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.9 0.1 0.2 4.1 0.0 0.5 132.0 0.0 2.4 105.9 836.2 0.7 0.6 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 20.2 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 14.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 4.6 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 48.7 179.8 0.0 0.0 33.0 0.0 0.0 0.0 0.0 MAMDC2 MGC21981 ENSG00000165072 "MAM domain containing 2" Q7Z304 9 70043848-70226972 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 74.5" "Cell type enhanced" "Detected in many" "Early spermatids: 42.5;Excitatory neurons: 37.0;Fibroblasts: 38.7;Inhibitory neurons: 42.9;Leydig cells: 96.6;Microglial cells: 45.9;Peritubular cells: 82.0;Sertoli cells: 39.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 55.7;HHSteC: 57.2;LHCN-M2: 75.0;TIME: 71.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021814, HPA022249" Uncertain Approved "Nuclear speckles,Plasma membrane" "Secreted in other tissues" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" "Nuclear speckles, Plasma membrane" "HPA021814: AB_1853508, HPA022249: AB_2139157" "unprognostic (1.88e-1)" "unprognostic (3.16e-3)" "unprognostic (2.21e-3)" "unprognostic (2.71e-2)" "unprognostic (4.30e-2)" "unprognostic (8.49e-2)" "unprognostic (1.27e-2)" "unprognostic (8.25e-2)" "unprognostic (5.91e-2)" "unprognostic (3.65e-2)" "unprognostic (1.92e-1)" "unprognostic (3.67e-1)" "unprognostic (3.03e-2)" "unprognostic (4.23e-3)" "unprognostic (2.35e-1)" "prognostic unfavorable (7.78e-4)" "unprognostic (2.79e-3)" 17.2 8.2 1.0 1.2 1.2 0.2 15.6 0.8 1.6 30.4 2.3 45.5 8.4 74.5 19.1 21.2 58.5 13.0 15.4 0.7 1.5 2.6 1.2 37.2 0.5 0.7 1.2 49.1 3.7 1.8 0.8 4.3 0.7 7.7 12.3 5.7 9.9 10.8 6.6 9.2 21.6 25.3 0.7 16.1 19.1 7.5 1.8 1.6 8.0 17.1 3.1 32.3 18.5 1.1 0.3 0.0 0.7 0.0 55.7 18.8 1.7 11.1 5.0 2.7 4.6 0.0 1.2 0.0 0.7 2.1 1.5 9.1 0.1 0.8 2.3 0.0 0.0 0.0 15.6 0.1 57.2 0.0 0.0 3.6 0.7 1.7 0.9 19.9 4.9 0.0 0.0 0.5 75.0 0.0 0.0 0.1 7.7 0.1 0.0 0.0 8.8 7.3 24.6 0.0 0.7 0.0 0.1 0.1 0.0 20.8 0.0 0.0 71.0 0.0 1.8 0.1 2.1 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.0 1.2 0.8 1.6 0.7 1.5 0.7 1.2 0.7 0.7 1.8 1.1 2.0 0.0 1.5 20.2 0.5 6.1 0.5 0.4 0.6 0.8 0.5 10.8 4.3 0.0 0.1 3.7 4.2 0.2 0.2 0.2 0.0 0.1 42.5 0.7 13.7 3.9 0.0 0.0 37.0 0.2 6.6 38.7 0.5 0.5 1.3 0.3 0.4 0.0 3.3 0.0 42.9 0.1 0.0 0.0 17.5 11.4 96.6 13.6 10.6 45.9 0.0 13.8 0.0 11.6 23.3 0.4 0.2 82.0 0.0 0.1 0.0 0.5 0.1 0.5 39.5 4.8 22.4 0.4 0.4 1.1 4.8 0.3 0.8 0.1 0.1 0.1 MAML3 "CAGH3, GDN, KIAA1816, MAM2, TNRC3" ENSG00000196782 "Mastermind like transcriptional coactivator 3" Q96JK9 4 139716753-140154184 "Predicted intracellular proteins" "Notch signaling pathway, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 125.6;Microglial cells: 355.1;Oligodendrocytes: 150.8" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 5 "cerebellum: 16.8" "Immune cell enhanced" "Detected in many" "basophil: 12.2" "Group enriched" "Detected in many" 5 "granulocytes: 12.2;NK-cells: 3.4" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 15.0;SCLC-21H: 15.7;SH-SY5Y: 23.9;WM-115: 20.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA037717 Approved Supported "Nuclear speckles" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 21: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear speckles" "HPA037717: AB_10794323" "unprognostic (1.83e-1)" "unprognostic (1.28e-1)" "unprognostic (1.17e-1)" "unprognostic (7.83e-3)" "unprognostic (4.73e-2)" "unprognostic (2.63e-1)" "unprognostic (3.36e-2)" "unprognostic (1.35e-1)" "unprognostic (1.48e-1)" "unprognostic (3.89e-1)" "unprognostic (5.52e-3)" "unprognostic (1.73e-1)" "prognostic favorable (7.60e-5)" "unprognostic (3.38e-1)" "unprognostic (1.20e-1)" "unprognostic (7.22e-2)" "unprognostic (2.88e-1)" 3.3 3.4 1.5 2.4 0.9 3.2 3.4 16.8 2.1 5.0 0.1 3.8 4.8 6.7 5.3 5.9 5.5 4.1 2.0 2.2 2.8 2.0 2.6 3.8 2.6 3.4 2.3 8.6 6.8 3.3 4.5 5.0 3.4 4.9 3.9 1.7 5.9 4.5 1.7 7.8 4.5 6.0 2.4 3.3 3.4 3.0 2.2 6.0 4.3 2.1 2.3 3.6 5.1 2.2 0.5 8.1 5.4 2.7 2.1 4.4 4.9 1.0 4.4 0.5 0.3 3.2 2.2 1.8 0.4 0.8 0.3 0.1 2.1 1.8 0.3 0.0 1.2 5.9 1.9 0.3 0.4 2.8 8.7 4.3 1.5 0.1 0.9 3.3 15.0 0.1 1.6 0.0 0.3 0.9 0.5 1.2 1.4 3.6 3.5 3.5 0.5 3.6 2.5 11.2 15.7 23.9 0.0 4.2 5.5 4.2 2.3 0.8 13.1 0.6 1.3 0.1 1.7 2.9 3.5 0.1 0.8 9.2 20.2 12.2 1.5 2.9 0.0 1.1 0.1 0.0 0.0 0.0 1.5 0.4 0.4 0.4 3.6 3.4 0.9 1.2 0.0 1.2 1.5 0.9 16.8 2.1 2.2 2.8 3.4 2.3 3.4 2.4 2.2 2.2 21.2 3.2 11.5 39.5 3.1 8.0 8.1 4.2 7.4 4.6 12.6 9.3 3.0 11.5 8.7 5.5 18.8 5.8 3.9 13.6 5.9 5.1 3.6 12.6 9.4 11.7 14.9 9.4 60.2 5.1 7.3 5.3 8.6 19.9 19.6 34.4 13.2 17.5 7.5 11.8 125.6 12.1 2.0 22.6 13.3 9.0 4.1 19.6 3.6 355.1 18.3 3.1 1.0 7.5 150.8 3.0 14.0 3.8 2.1 5.7 8.2 6.1 7.2 3.7 0.0 2.9 13.7 0.5 2.2 19.0 13.5 8.2 5.3 8.5 11.0 8.9 MAMSTR "FLJ36070, MASTR" ENSG00000176909 "MEF2 activating motif and SAP domain containing transcriptional regulator" Q6ZN01 19 48712725-48719725 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adrenal gland: 32.4;skeletal muscle: 88.9;tongue: 22.6" "Cell type enhanced" "Detected in many" "Theca cells: 10.1" "Cancer enhanced" "Detected in all" "ovarian cancer: 7.0" "Region enhanced" "Detected in many" "cerebellum: 7.9" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 7.2;RH-30: 16.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA049765 Approved "Nuclear speckles" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" "Nuclear speckles" "HPA049765: AB_2680870" "unprognostic (6.00e-2)" "unprognostic (3.20e-2)" "unprognostic (5.98e-2)" "unprognostic (6.07e-2)" "unprognostic (1.65e-1)" "unprognostic (6.50e-3)" "unprognostic (4.34e-4)" "unprognostic (2.11e-2)" "unprognostic (4.69e-1)" "unprognostic (2.69e-2)" "unprognostic (2.89e-2)" "unprognostic (4.65e-2)" "unprognostic (1.49e-1)" "unprognostic (1.07e-2)" "unprognostic (2.79e-1)" "unprognostic (4.84e-2)" "unprognostic (1.39e-2)" 4.6 32.4 1.7 0.8 2.0 0.3 1.8 7.9 3.7 6.2 0.0 2.5 0.6 8.0 1.4 3.5 8.0 1.0 4.0 2.0 0.2 2.4 0.4 1.4 0.6 0.6 0.8 8.7 1.9 3.0 3.8 1.6 0.9 2.4 0.7 0.5 2.9 1.9 88.9 2.1 1.2 4.6 0.2 6.1 1.6 9.2 0.6 0.5 1.2 22.6 0.6 2.0 4.6 1.2 0.5 1.3 1.4 3.5 2.7 4.5 1.3 4.8 3.8 2.3 3.6 1.4 0.9 0.7 0.2 4.4 1.3 1.0 0.1 0.8 0.9 0.5 1.6 0.3 0.6 7.2 1.4 0.1 0.9 2.8 0.9 3.2 0.4 3.1 0.8 1.3 0.3 0.9 1.5 0.6 1.1 0.5 0.1 1.1 1.0 1.3 16.6 0.4 0.2 0.3 1.5 2.8 0.7 0.3 0.3 0.3 0.5 0.0 0.3 4.7 0.8 3.8 0.6 1.0 0.6 0.5 1.7 0.5 0.9 0.0 0.2 0.5 1.6 0.4 1.0 1.3 1.7 1.6 0.4 2.1 1.6 1.5 0.2 0.3 0.4 1.3 0.8 0.3 1.7 2.0 7.9 3.7 2.0 0.2 0.6 0.8 0.9 0.2 0.6 1.2 2.4 0.0 0.0 2.6 1.3 0.9 1.8 1.5 4.6 1.8 1.4 2.2 2.9 0.0 2.3 1.8 2.1 0.8 0.5 0.6 5.9 1.7 0.8 0.8 3.5 3.8 0.0 1.3 2.9 1.0 2.9 4.9 1.1 1.6 0.0 6.1 4.6 0.3 1.1 0.0 2.0 0.7 2.0 0.3 2.2 1.7 5.6 1.6 7.2 0.0 1.2 5.3 2.1 1.5 1.2 0.5 0.0 6.0 1.5 0.6 1.1 0.6 0.4 2.9 0.0 5.1 4.7 0.7 1.6 2.4 0.9 1.0 1.8 10.1 0.8 1.6 MAP3K7 "MEKK7, TAK1" ENSG00000135341 "Mitogen-activated protein kinase kinase kinase 7" O43318 6 90513573-90587072 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 137.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007633, HPA075335" Approved Supported "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 21: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "Nuclear speckles, Plasma membrane" "HPA007633: AB_1079359, HPA075335: " "unprognostic (1.48e-1)" "unprognostic (3.45e-2)" "unprognostic (1.35e-1)" "unprognostic (6.48e-2)" "unprognostic (1.44e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (3.51e-4)" "unprognostic (9.77e-2)" "unprognostic (6.51e-2)" "unprognostic (1.98e-2)" "unprognostic (1.44e-1)" "unprognostic (2.79e-1)" "unprognostic (2.56e-3)" "unprognostic (4.76e-2)" "unprognostic (1.95e-1)" "unprognostic (2.08e-1)" "unprognostic (1.17e-1)" 11.8 12.5 13.1 12.5 15.1 8.7 14.3 15.6 17.3 14.3 11.7 11.6 9.2 16.6 16.5 10.6 11.0 12.7 16.9 14.7 14.9 11.4 11.6 10.4 16.4 15.3 13.7 15.8 9.7 16.3 13.0 17.4 15.8 14.9 10.9 23.5 12.1 13.3 16.9 13.9 9.8 14.0 15.3 17.6 10.8 9.9 13.8 20.8 14.7 18.4 16.8 14.3 12.2 22.4 16.7 14.4 41.3 35.6 29.5 39.1 29.0 32.7 37.7 28.8 36.1 18.6 15.5 36.9 20.4 35.6 25.6 17.3 26.3 25.5 48.7 19.0 27.7 32.9 19.9 24.9 30.8 36.9 24.4 32.5 30.5 28.2 34.2 33.1 27.4 31.8 67.0 29.3 41.8 20.3 17.2 31.2 34.0 25.7 18.0 29.3 73.9 18.0 24.2 18.4 20.8 29.5 22.9 15.6 24.8 32.2 15.5 64.7 26.5 23.3 14.7 21.6 30.9 25.9 24.7 15.8 35.7 39.7 35.0 18.2 11.5 18.4 12.8 15.9 14.5 13.0 12.3 12.5 14.6 9.9 13.7 13.4 11.5 17.9 17.6 8.9 20.8 13.4 13.1 15.1 15.6 17.3 14.7 14.9 15.3 13.7 15.8 15.3 13.8 22.4 16.1 16.0 26.9 47.0 24.3 36.3 20.8 19.5 21.6 23.3 17.9 12.3 31.0 14.3 16.9 16.5 27.1 31.8 17.8 12.4 7.9 17.6 3.6 10.9 19.8 21.2 12.1 14.1 85.7 20.9 34.6 23.2 16.3 14.8 13.9 25.9 25.7 20.7 24.3 28.6 63.8 13.7 20.3 27.3 24.6 3.2 26.8 21.7 21.4 36.5 35.2 19.6 16.5 50.8 137.2 20.1 9.1 41.0 18.8 30.1 11.1 16.6 21.4 21.5 19.7 28.0 18.5 25.9 24.9 21.3 37.2 48.4 22.7 18.1 15.1 24.8 MAPK1 "ERK, ERK2, MAPK2, p41mapk, PRKM1, PRKM2" ENSG00000100030 "Mitogen-activated protein kinase 1" P28482 22 21759657-21867680 "Cancer-related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Kinase, Repressor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 341.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003995, CAB004229, HPA005700, HPA030069, CAB079930, CAB079932, CAB079933" Enhanced Supported "Nuclear speckles,Cytosol" NA NA 140000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 65: Brain - Ion transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Nuclear speckles" "CAB004229: AB_627547, CAB079930: , CAB079932: , CAB079933: , HPA003995: AB_1078751, HPA005700: AB_1078750, HPA030069: AB_10602035" "unprognostic (9.41e-3)" "unprognostic (2.68e-1)" "unprognostic (2.50e-3)" "unprognostic (4.17e-1)" "unprognostic (4.44e-3)" "unprognostic (1.72e-1)" "prognostic unfavorable (4.95e-4)" "unprognostic (2.29e-1)" "unprognostic (1.67e-1)" "unprognostic (1.58e-1)" "unprognostic (8.43e-3)" "unprognostic (1.04e-1)" "unprognostic (1.35e-2)" "unprognostic (2.08e-1)" "unprognostic (1.94e-1)" "unprognostic (1.41e-1)" "unprognostic (6.49e-2)" 31.1 33.1 64.8 35.9 84.4 41.2 29.8 37.3 80.9 31.4 32.9 36.1 25.8 29.6 30.1 43.0 29.0 28.9 42.2 91.3 46.4 42.1 34.2 38.5 36.8 29.1 45.1 29.2 38.1 51.7 12.0 33.1 35.9 32.8 36.2 30.3 28.9 32.7 38.1 45.0 29.5 39.1 43.8 40.5 33.9 43.7 60.1 44.4 46.1 41.9 41.9 35.5 18.9 43.2 78.7 48.0 60.5 37.2 75.9 76.7 25.9 84.7 77.5 73.2 72.0 43.8 40.8 45.8 41.3 112.7 67.5 74.6 73.9 67.9 97.8 180.4 72.1 78.9 43.0 67.7 73.5 113.2 80.5 56.9 60.1 89.4 81.6 58.0 101.7 45.4 341.9 50.5 97.5 36.6 72.0 38.5 24.4 104.5 46.8 79.4 149.6 13.2 55.5 62.9 50.0 28.6 91.5 64.2 57.2 60.4 42.4 47.1 90.1 61.5 79.6 71.9 54.2 47.1 59.4 65.8 60.0 60.0 68.4 1.4 4.9 7.2 15.9 6.0 4.9 2.3 3.6 6.0 4.1 2.6 3.5 6.1 16.5 9.3 6.9 4.0 3.4 4.0 64.8 84.4 37.3 80.9 91.3 46.4 29.1 45.1 35.9 43.8 60.1 43.2 36.8 48.1 35.8 97.6 44.0 60.2 28.4 25.1 28.5 25.5 32.5 24.5 41.5 42.9 31.2 51.5 54.2 21.8 151.7 74.4 19.6 28.5 49.0 33.5 40.3 39.9 59.6 63.8 109.2 39.2 23.2 38.4 52.0 45.0 92.8 28.8 52.1 63.5 53.2 28.6 91.2 42.2 26.4 89.0 77.1 14.7 32.6 74.9 40.9 68.4 75.0 35.8 143.2 82.4 75.1 45.3 35.2 44.4 37.0 43.8 32.8 46.0 32.2 22.4 32.9 44.6 37.3 74.1 53.4 44.9 61.8 19.2 91.4 43.3 38.6 38.8 MAPK12 "ERK6, p38gamma, PRKM12, SAPK-3, SAPK3" ENSG00000188130 "Mitogen-activated protein kinase 12" P53778 22 50245450-50261716 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "skeletal muscle: 279.7;tongue: 120.9" "Cell type enhanced" "Detected in many" "Adipocytes: 23.1;Astrocytes: 22.9;Endothelial cells: 15.8;Hepatic stellate cells: 20.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 31.6" "Low region specificity" "Detected in all" "CAB025483, HPA054562" Enhanced Approved "Nuclear speckles,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles" Cytosol "CAB025483: , HPA054562: AB_2682524" "unprognostic (3.68e-2)" "unprognostic (1.72e-1)" "unprognostic (4.53e-3)" "unprognostic (1.54e-1)" "unprognostic (3.22e-2)" "unprognostic (6.35e-3)" "unprognostic (3.90e-3)" "unprognostic (3.16e-2)" "unprognostic (6.02e-2)" "unprognostic (5.70e-2)" "unprognostic (3.48e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (5.00e-6)" "unprognostic (2.57e-1)" "unprognostic (8.88e-2)" "unprognostic (1.11e-2)" "unprognostic (4.28e-3)" 11.0 2.3 15.6 3.8 16.5 1.3 7.9 15.5 21.2 11.4 9.2 4.7 3.5 19.0 9.8 6.3 11.2 4.4 15.7 15.1 16.5 10.7 1.4 6.8 4.1 17.1 14.9 10.6 1.8 4.3 25.1 4.1 14.6 10.0 1.1 1.4 4.3 6.9 279.7 1.5 4.4 8.6 14.6 4.3 5.0 4.6 15.2 0.9 3.2 120.9 1.4 6.0 5.9 13.9 23.2 13.9 5.3 16.3 12.4 13.5 7.5 17.5 15.1 28.2 18.3 19.6 7.2 45.1 23.4 19.6 16.8 15.4 24.3 3.4 5.5 12.8 34.0 29.2 46.7 24.9 37.7 28.4 54.5 29.8 6.0 7.2 0.0 16.8 33.2 4.0 26.3 38.5 13.4 12.8 0.0 35.4 15.9 7.6 22.5 41.4 14.2 43.9 17.5 3.0 18.0 6.5 13.3 0.5 22.1 4.2 7.1 29.6 18.7 28.5 26.1 6.6 11.2 9.3 7.3 24.5 7.2 24.7 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 15.6 16.5 15.5 21.2 15.1 16.5 17.1 14.9 14.6 14.6 15.2 13.9 23.1 0.0 3.2 22.9 1.6 0.8 0.7 3.3 1.2 5.5 1.2 1.3 8.8 4.3 0.8 0.0 0.0 0.3 0.9 0.3 1.9 0.5 0.3 0.6 10.0 15.8 1.8 1.7 9.8 0.0 2.8 5.3 2.6 0.7 10.8 0.6 20.7 0.9 6.3 1.7 6.5 0.2 8.2 2.2 0.8 1.9 6.5 2.2 0.0 6.5 0.6 8.1 0.0 5.0 0.9 0.5 0.0 3.8 2.8 3.6 0.4 8.0 0.9 2.2 6.6 3.3 3.0 0.7 12.1 0.8 0.6 0.4 2.2 3.2 0.3 0.2 MAPK14 "CSBP1, CSBP2, CSPB1, Mxi2, p38, PRKM14, PRKM15" ENSG00000112062 "Mitogen-activated protein kinase 14" Q16539 6 36027677-36111236 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 104.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 79.0;neutrophil: 24.9" "Lineage enriched" "Detected in all" 7 "granulocytes: 79.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010285, CAB040578, HPA051825" Approved Supported "Nuclear speckles,Cytosol" NA NA 970000 "Cluster 38: Basophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nuclear speckles" Cytosol "CAB010285: AB_632140, CAB040578: , HPA051825: " "unprognostic (6.76e-3)" "unprognostic (6.28e-2)" "unprognostic (6.30e-3)" "unprognostic (3.30e-3)" "unprognostic (6.98e-2)" "unprognostic (4.04e-2)" "unprognostic (8.10e-2)" "unprognostic (1.93e-1)" "unprognostic (2.20e-3)" "unprognostic (8.39e-2)" "unprognostic (6.27e-2)" "unprognostic (1.10e-1)" "unprognostic (1.47e-2)" "unprognostic (3.66e-3)" "unprognostic (6.66e-2)" "unprognostic (3.25e-1)" "unprognostic (1.58e-1)" 29.9 26.1 15.2 31.5 16.5 89.3 23.8 19.2 17.1 30.8 19.3 26.6 27.9 37.2 15.8 32.3 25.7 23.5 25.7 17.2 18.2 23.9 41.4 28.3 28.0 11.5 11.7 22.2 18.3 20.6 19.3 44.6 12.1 19.6 29.0 14.8 21.0 24.4 33.5 34.4 26.2 39.0 13.0 44.9 22.5 9.1 18.1 38.6 31.1 31.9 33.3 32.3 29.2 13.8 49.7 26.7 28.3 44.9 60.0 59.8 62.2 50.2 64.8 58.7 60.3 67.3 24.8 40.4 49.6 54.9 28.0 34.8 47.2 43.7 60.9 47.3 37.6 94.9 37.2 53.1 33.2 60.3 54.9 43.1 40.5 42.2 40.9 47.6 67.1 67.2 52.4 49.1 40.3 21.1 62.2 62.5 17.0 29.9 26.2 71.7 45.5 37.5 38.5 67.6 21.8 17.2 46.0 33.5 50.3 34.1 40.8 99.9 47.9 52.5 29.8 33.6 47.7 24.3 59.8 39.5 23.2 112.1 43.9 79.0 10.3 6.3 4.5 7.2 5.5 3.1 4.4 5.1 8.2 5.3 4.6 4.7 24.9 6.1 10.8 4.0 5.8 5.1 15.2 16.5 19.2 17.1 17.2 18.2 11.5 11.7 12.1 13.0 18.1 13.8 24.4 32.1 13.9 37.2 22.6 15.9 11.0 13.9 28.5 18.9 14.0 11.7 25.0 14.3 18.5 18.4 31.3 45.4 26.8 29.0 1.9 13.9 3.6 18.7 25.8 22.6 16.8 47.1 104.9 11.3 18.7 25.9 21.9 30.7 21.0 17.7 28.9 52.9 25.3 11.8 79.2 25.4 10.2 51.7 24.9 5.2 24.5 38.5 10.6 52.5 58.7 10.9 39.1 46.8 69.6 22.8 16.2 26.7 27.7 10.3 33.7 17.2 20.9 22.5 13.1 20.4 15.7 9.9 8.5 27.1 19.0 23.9 28.0 12.3 18.8 10.7 MAPK9 "JNK2, p54a, PRKM9, SAPK" ENSG00000050748 "Mitogen-activated protein kinase 9" P45984 5 180233143-180292099 "Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 64.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 16.3" "Lineage enriched" "Detected in all" 6 "granulocytes: 16.3" "Cell line enhanced" "Detected in all" "HDLM-2: 211.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008910, HPA072462" Enhanced Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "Nuclear speckles" "CAB008910: , HPA072462: " "unprognostic (5.04e-3)" "unprognostic (2.06e-2)" "prognostic favorable (1.11e-4)" "unprognostic (8.53e-2)" "unprognostic (1.75e-1)" "unprognostic (5.06e-3)" "unprognostic (6.83e-3)" "unprognostic (3.16e-1)" "unprognostic (4.93e-2)" "unprognostic (3.76e-1)" "unprognostic (5.97e-2)" "unprognostic (1.36e-1)" "unprognostic (1.50e-1)" "unprognostic (2.13e-1)" "unprognostic (2.29e-1)" "unprognostic (9.38e-3)" "unprognostic (2.40e-1)" 19.3 21.1 28.4 18.4 32.6 21.3 17.5 36.5 41.4 17.7 7.2 22.4 18.5 15.3 16.2 15.4 15.3 13.9 25.7 34.2 25.8 21.1 17.7 19.5 19.9 25.7 19.7 14.6 45.7 30.1 12.9 19.7 26.4 20.0 26.4 21.4 19.1 21.6 40.8 11.7 19.3 19.9 16.9 16.6 22.5 17.8 22.2 22.5 26.7 34.8 21.1 17.4 11.1 29.8 52.7 42.7 37.0 46.5 35.7 39.3 79.4 49.6 43.5 40.5 40.5 56.4 36.7 55.9 83.1 52.6 89.3 39.6 38.4 82.8 47.5 211.8 36.9 23.2 46.8 40.3 27.1 49.0 39.2 29.3 36.5 39.5 38.0 42.5 48.9 43.0 26.2 39.5 55.9 68.9 49.2 20.4 25.8 64.8 25.0 46.9 62.7 26.9 30.8 49.7 42.5 29.9 58.2 55.8 40.4 45.8 56.9 41.7 35.5 48.3 49.2 69.3 75.2 28.2 35.6 37.9 51.5 44.8 32.9 16.3 0.5 2.2 1.6 1.1 1.6 0.8 1.2 1.4 0.8 1.3 0.8 0.9 0.7 1.2 2.3 1.2 2.7 0.3 28.4 32.6 36.5 41.4 34.2 25.8 25.7 19.7 26.4 16.9 22.2 29.8 20.5 32.1 14.4 26.1 10.5 10.1 7.0 6.5 9.1 21.9 16.8 12.2 27.6 12.8 8.5 9.2 16.7 15.3 20.5 20.7 5.9 8.0 1.2 17.6 14.2 12.2 16.7 9.5 62.5 16.0 23.3 11.1 15.8 18.6 11.4 14.5 12.5 16.7 11.7 13.5 64.3 17.9 4.1 24.2 20.5 3.1 10.5 15.0 5.4 31.9 13.9 11.4 15.5 25.1 32.9 13.1 12.3 13.5 15.6 10.2 13.4 11.0 6.9 14.8 13.1 13.5 13.7 17.0 17.1 9.4 11.4 17.8 14.7 8.2 15.4 8.8 MAPT "DDPAC, FLJ31424, FTDP-17, MAPTL, MGC138549, MSTD, MTBT1, MTBT2, PPND, PPP1R103, tau" ENSG00000186868 "Microtubule associated protein tau" P10636 17 45894527-46028334 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Alzheimer disease, Disease variant, FDA approved drug targets, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 67.7;skeletal muscle: 79.0" "Cell type enhanced" "Detected in many" "Astrocytes: 142.4;Bipolar cells: 314.4;Early spermatids: 199.9;Excitatory neurons: 189.2;Horizontal cells: 361.7;Inhibitory neurons: 153.7;Late spermatids: 416.6;Muller glia cells: 145.7;Oligodendrocytes: 163.8" "Cancer enhanced" "Detected in many" "breast cancer: 9.5;glioma: 13.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.7" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 5 "HDLM-2: 69.0;SCLC-21H: 21.1;T-47d: 34.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000151, HPA048895, HPA069524, HPA069570, CAB072344" Enhanced Supported "Nuclear speckles,Plasma membrane" "Secreted to blood" NA NA 7100 "Cluster 35: T-regs - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "Nuclear speckles" "CAB000151: , CAB072344: , HPA048895: AB_2680550, HPA069524: AB_2686145, HPA069570: AB_2686155" "unprognostic (1.78e-3)" "unprognostic (7.51e-2)" "unprognostic (3.71e-2)" "unprognostic (8.40e-5)" "unprognostic (1.40e-1)" "unprognostic (1.31e-2)" "unprognostic (4.06e-5)" "unprognostic (6.04e-2)" "unprognostic (2.19e-2)" "unprognostic (3.49e-2)" "unprognostic (3.88e-3)" "unprognostic (2.65e-1)" "unprognostic (1.72e-3)" "unprognostic (6.53e-2)" "unprognostic (3.43e-1)" "unprognostic (1.85e-2)" "unprognostic (5.47e-2)" 4.7 4.3 26.2 0.3 27.1 0.0 9.1 8.3 67.7 2.4 0.0 8.4 0.5 1.0 0.2 8.4 1.0 0.8 9.4 30.0 20.4 14.7 0.6 0.8 0.3 11.6 11.4 0.6 1.5 2.9 29.5 3.4 22.4 5.4 0.3 17.6 8.5 3.4 79.0 6.3 1.8 0.3 2.7 0.4 1.7 20.3 14.8 0.4 0.9 27.4 0.2 10.2 2.3 19.7 2.9 0.5 0.3 6.4 0.3 0.9 1.8 0.1 0.3 0.1 0.0 0.2 0.0 0.0 0.6 0.4 0.5 0.1 2.3 0.3 0.0 69.0 3.4 0.0 0.3 4.2 0.0 0.1 0.1 0.0 0.5 0.1 0.3 0.1 0.0 4.4 0.7 3.6 0.0 7.7 1.0 0.2 0.2 0.7 2.0 0.0 4.0 8.5 0.0 9.1 21.1 9.1 2.5 0.0 1.8 1.0 34.7 0.1 0.1 0.3 0.8 1.7 0.3 0.9 0.3 0.0 0.6 2.0 0.5 0.1 0.0 0.0 0.2 0.7 0.2 0.0 0.1 0.5 0.0 0.0 0.2 0.3 0.2 0.1 1.7 0.0 0.7 0.0 26.2 27.1 8.3 67.7 30.0 20.4 11.6 11.4 22.4 2.7 14.8 19.7 1.9 0.0 9.8 142.4 1.0 1.0 1.4 0.2 1.2 314.4 26.7 21.2 35.2 0.0 0.1 1.8 64.6 0.2 0.4 0.1 7.9 0.5 199.9 0.4 1.7 1.8 0.0 0.0 189.2 0.4 9.1 3.7 0.5 1.3 4.5 1.6 1.1 0.5 0.3 361.7 153.7 0.0 2.0 0.6 1.7 416.6 2.8 0.8 5.4 8.4 0.7 145.7 0.0 129.7 163.8 0.6 0.0 2.6 0.1 2.5 0.1 76.1 0.0 28.3 0.0 28.2 6.0 18.4 8.1 22.7 3.3 0.3 1.5 0.8 0.3 0.6 MAST3 KIAA0561 ENSG00000099308 "Microtubule associated serine/threonine kinase 3" O60307 19 18097793-18151692 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 62.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 62.6;Oligodendrocytes: 63.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035061, HPA035062" Uncertain Approved "Nuclear speckles" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear speckles" "HPA035061: AB_10670585, HPA035062: AB_10671508" "unprognostic (5.94e-3)" "unprognostic (4.75e-2)" "unprognostic (1.70e-1)" "unprognostic (1.02e-1)" "unprognostic (3.38e-1)" "prognostic favorable (2.97e-4)" "unprognostic (1.93e-1)" "unprognostic (4.63e-2)" "unprognostic (1.43e-1)" "unprognostic (3.21e-1)" "prognostic favorable (7.01e-4)" "unprognostic (2.58e-1)" "unprognostic (1.64e-3)" "unprognostic (1.02e-2)" "unprognostic (3.61e-1)" "unprognostic (1.58e-3)" "unprognostic (1.26e-3)" 4.9 4.8 49.9 9.2 53.4 14.4 3.7 0.0 62.1 9.4 0.0 7.3 9.6 5.3 4.7 3.3 7.1 3.1 3.7 61.6 0.0 7.6 14.5 9.1 11.2 5.3 1.9 7.1 20.2 5.0 15.5 2.6 4.3 5.6 4.3 1.0 4.8 3.9 3.0 7.3 12.4 3.0 0.0 19.2 4.5 3.6 13.7 4.2 4.5 1.6 10.1 3.7 4.9 47.4 3.5 5.1 2.3 10.2 6.7 5.4 5.5 3.5 2.2 2.4 3.4 5.2 4.7 9.0 5.1 3.5 2.6 1.9 3.4 2.0 1.7 7.7 4.2 4.1 5.7 8.3 5.6 2.2 13.2 6.2 5.7 3.6 1.4 3.2 1.1 6.1 4.3 5.8 2.8 6.3 4.7 7.3 2.4 7.7 6.2 12.6 2.0 6.6 1.9 1.5 3.8 6.2 4.9 2.8 2.1 1.6 3.2 5.1 4.0 3.0 3.2 13.1 1.5 6.2 9.0 8.0 6.7 11.6 2.9 0.3 6.2 14.8 11.7 8.0 8.4 5.9 6.3 4.7 3.2 5.9 4.9 8.4 32.9 8.1 14.7 15.4 7.6 6.1 49.9 53.4 0.0 62.1 61.6 0.0 5.3 1.9 4.3 0.0 13.7 47.4 2.6 6.4 9.4 5.5 13.5 0.5 0.8 2.8 2.8 3.0 2.6 2.8 1.5 7.2 3.6 9.2 2.1 0.5 19.0 30.0 3.9 2.9 9.3 2.8 5.4 3.8 2.4 1.3 62.6 10.5 1.5 3.4 7.7 1.5 2.5 3.0 4.6 16.3 7.7 0.0 6.1 8.5 0.0 21.7 6.3 30.8 4.1 13.3 5.4 19.7 19.6 0.9 32.0 8.0 63.7 7.1 7.9 6.8 5.1 1.2 16.7 8.8 4.2 0.7 0.0 2.1 3.0 0.6 3.9 2.3 2.3 0.4 11.0 5.3 13.0 0.6 MBD4 MED1 ENSG00000129071 "Methyl-CpG binding domain 4, DNA glycosylase" O95243 3 129430947-129440179 "Cancer-related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Hydrolase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002031 Supported Supported "Nuclear speckles" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Nuclear speckles" "HPA002031: AB_1079319" "unprognostic (2.70e-2)" "unprognostic (3.48e-3)" "unprognostic (1.18e-2)" "unprognostic (6.37e-2)" "unprognostic (4.31e-2)" "unprognostic (7.11e-2)" "unprognostic (4.70e-2)" "unprognostic (3.25e-2)" "unprognostic (2.02e-2)" "unprognostic (5.73e-2)" "prognostic unfavorable (2.18e-4)" "prognostic unfavorable (4.75e-4)" "prognostic unfavorable (2.73e-6)" "unprognostic (9.27e-2)" "unprognostic (1.59e-2)" "unprognostic (8.58e-2)" "unprognostic (3.35e-2)" 18.6 18.4 16.8 34.0 18.4 44.2 21.6 19.6 20.7 33.2 16.8 19.3 23.7 23.3 24.8 16.4 19.3 21.3 25.3 17.0 17.4 25.4 38.0 22.9 66.5 17.5 17.2 30.3 22.9 18.1 19.3 19.7 17.7 18.7 22.9 19.6 19.5 17.8 25.8 23.7 27.5 19.7 17.3 39.2 27.8 17.3 18.4 30.0 19.3 22.3 74.0 18.5 17.5 20.6 46.2 27.4 32.5 36.5 36.8 32.8 37.5 39.0 36.9 36.7 43.3 33.8 30.1 64.6 31.1 24.5 33.7 40.7 25.2 24.1 44.2 37.0 16.6 38.9 32.0 24.6 58.7 71.2 49.2 39.1 33.8 31.2 27.4 36.5 35.1 37.2 43.9 47.1 27.5 43.3 41.4 50.0 28.7 38.8 23.5 38.7 19.2 44.7 40.9 22.7 36.5 20.3 49.3 25.3 42.5 28.0 32.3 62.5 23.6 34.5 26.3 37.6 26.2 31.9 20.9 111.9 29.4 40.1 29.2 80.3 25.0 35.2 31.1 23.1 24.0 116.5 33.2 30.9 21.0 110.8 40.6 33.3 43.0 28.9 30.0 25.2 31.5 25.6 16.8 18.4 19.6 20.7 17.0 17.4 17.5 17.2 17.7 17.3 18.4 20.6 36.5 19.2 52.9 15.3 111.2 17.3 32.5 38.4 29.6 37.0 26.7 29.6 35.9 27.1 36.4 44.1 18.8 49.2 61.4 22.4 45.0 32.1 19.8 49.6 41.2 33.5 33.6 46.3 18.1 69.0 46.2 35.6 55.0 45.0 58.9 33.1 31.4 32.1 71.8 21.9 12.8 27.5 40.7 41.8 24.7 10.6 32.9 48.0 21.4 24.4 62.9 21.2 54.6 14.1 22.0 39.3 23.4 36.5 75.5 31.1 29.4 55.5 39.5 46.3 39.5 39.6 30.9 49.5 71.6 30.4 19.6 37.1 54.2 33.2 26.3 35.6 MECOM "EVI1, KMT8E, MDS1, MDS1-EVI1, PRDM3" ENSG00000085276 "MDS1 and EVI1 complex locus" Q03112 3 169083499-169663775 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 73.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 184.8;Collecting duct cells: 125.0;Gastric mucus-secreting cells: 111.1;Glandular and luminal cells: 107.7;Microglial cells: 346.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 55.5;RPTEC TERT1: 71.2;RT4: 119.6;TIME: 53.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046537 Supported Supported "Nuclear speckles" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 46: Fibroblasts - ECM organization" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "Nuclear speckles" "HPA046537: AB_2679689" "unprognostic (4.09e-2)" "unprognostic (1.96e-1)" "unprognostic (3.24e-3)" "unprognostic (7.29e-2)" "unprognostic (2.87e-2)" "unprognostic (2.53e-1)" "unprognostic (1.83e-2)" "unprognostic (4.77e-3)" "unprognostic (1.53e-2)" "unprognostic (3.27e-3)" "prognostic unfavorable (2.59e-4)" "unprognostic (1.87e-1)" "unprognostic (2.60e-3)" "unprognostic (6.54e-2)" "unprognostic (1.03e-1)" "unprognostic (2.81e-2)" "unprognostic (3.37e-3)" 16.0 0.9 7.3 7.3 7.2 1.4 12.3 8.5 7.3 21.3 2.4 24.9 19.8 17.3 4.4 13.5 23.4 8.3 13.0 4.9 6.3 41.3 1.4 25.5 1.5 9.1 7.2 2.3 23.3 1.7 4.2 17.4 8.9 6.9 30.0 1.8 8.8 8.0 4.3 2.6 10.2 8.0 4.1 6.2 73.3 3.0 8.1 2.0 5.7 12.0 5.3 30.4 7.5 6.3 25.8 0.7 0.9 0.2 3.7 2.7 1.1 3.7 4.2 1.1 2.2 10.7 26.1 0.9 39.1 0.6 5.5 13.4 10.2 15.7 3.1 1.4 16.6 16.7 7.6 1.1 0.4 0.3 5.1 5.7 2.2 1.0 12.1 12.0 55.5 1.4 13.0 1.8 10.3 9.8 0.9 0.4 1.7 13.5 6.6 9.8 13.1 0.3 71.2 119.6 1.0 3.1 1.3 6.7 0.3 1.5 7.1 1.1 53.4 9.7 6.6 2.5 16.9 1.4 0.7 0.9 4.8 1.0 1.6 0.9 0.4 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.5 0.2 0.0 0.0 0.3 0.4 0.5 1.6 0.1 0.0 7.3 7.2 8.5 7.3 4.9 6.3 9.1 7.2 8.9 4.1 8.1 6.3 80.2 60.9 184.8 16.0 0.6 2.2 33.3 29.4 10.2 0.0 1.2 0.9 11.4 2.8 69.6 125.0 0.0 1.1 0.1 25.5 52.8 1.6 10.4 71.9 5.8 70.5 19.9 7.4 10.3 75.4 0.2 4.8 111.1 107.7 9.5 0.8 69.3 0.2 0.0 0.0 9.1 29.0 20.3 0.6 1.9 3.2 0.3 2.6 1.8 346.6 1.0 0.0 0.0 6.0 13.8 49.8 19.3 0.0 0.3 13.9 6.2 0.7 53.2 0.1 0.0 1.4 5.7 3.0 1.2 39.4 1.4 0.4 1.3 0.5 53.9 45.4 MED17 "CRSP6, CRSP77, DRIP80, SRB4, TRAP80" ENSG00000042429 "Mediator complex subunit 17" Q9NVC6 11 93784227-93814963 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 4 "cerebellum: 2.3;cerebral cortex: 1.3;white matter: 1.7" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA046619 Approved "Nuclear speckles,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" Cytosol "HPA046619: " "prognostic unfavorable (4.94e-4)" "unprognostic (2.92e-1)" "unprognostic (2.72e-3)" "unprognostic (1.38e-1)" "unprognostic (6.71e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (4.04e-6)" "unprognostic (1.50e-1)" "unprognostic (4.48e-3)" "unprognostic (7.73e-2)" "unprognostic (1.41e-1)" "unprognostic (4.59e-2)" "unprognostic (1.02e-2)" "unprognostic (1.77e-1)" "unprognostic (2.22e-1)" "unprognostic (5.56e-3)" "unprognostic (1.48e-1)" 1.3 0.9 0.2 1.5 0.4 1.5 1.0 2.3 1.3 1.4 1.2 1.5 0.4 1.8 1.0 1.0 1.5 0.6 1.7 0.3 0.2 0.9 0.5 1.1 1.1 0.4 0.2 1.6 1.4 0.5 0.8 1.3 0.3 1.0 0.5 1.1 1.0 0.7 1.6 1.1 2.1 1.0 0.1 2.3 1.7 0.9 0.4 1.3 0.9 1.1 1.0 1.0 1.0 1.7 3.3 1.1 2.7 5.9 3.3 0.4 5.3 7.3 2.5 4.7 2.8 5.9 6.6 5.3 11.6 0.6 1.3 9.8 2.5 1.4 1.3 6.5 2.9 6.0 3.7 1.7 1.7 10.5 10.1 1.3 3.4 3.5 2.1 1.1 1.9 1.4 5.5 3.4 2.7 1.0 12.3 3.1 5.1 0.7 0.8 9.5 7.8 4.4 2.8 2.3 9.7 12.3 5.8 4.7 2.8 0.6 7.2 2.5 6.5 7.2 5.7 9.9 6.3 4.9 10.1 3.9 1.9 7.2 8.5 3.3 3.0 7.6 4.0 3.7 4.5 8.2 5.1 5.0 3.8 5.8 5.2 2.9 3.3 6.7 2.2 4.5 5.3 3.5 0.2 0.4 2.3 1.3 0.3 0.2 0.4 0.2 0.3 0.1 0.4 1.7 7.7 6.4 9.3 16.3 32.1 30.1 39.6 19.4 25.6 24.6 10.1 4.6 15.5 14.3 19.5 7.3 16.7 39.3 25.5 12.4 1.9 15.8 1.0 9.3 14.9 14.2 26.8 9.7 25.8 9.7 27.4 17.2 17.3 13.6 10.8 22.9 16.8 8.6 14.5 15.2 27.7 13.4 16.2 15.5 27.0 3.0 15.8 12.8 14.2 19.7 18.4 13.4 23.7 22.1 25.1 10.4 14.8 21.4 25.6 26.9 13.8 2.7 19.4 43.9 65.7 19.3 16.4 23.1 16.3 18.1 25.7 34.1 28.1 10.4 17.6 36.3 MKX "C10orf48, IRXL1, MGC39616" ENSG00000150051 "Mohawk homeobox" Q8IYA7 10 27672874-27746060 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 11.1;prostate: 15.7" "Cell type enhanced" "Detected in some" "Excitatory neurons: 39.1;Granulosa cells: 11.1;Inhibitory neurons: 15.7;Peritubular cells: 7.2;Respiratory ciliated cells: 7.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 51.3;BJ hTERT+: 29.4;BJ hTERT+ SV40 Large T+: 33.1;BJ hTERT+ SV40 Large T+ RasG12V: 22.6;fHDF/TERT166: 148.4;SiHa: 21.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA006927 Uncertain Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Nuclear speckles" "HPA006927: AB_1853981" "unprognostic (2.04e-1)" "unprognostic (2.59e-2)" "unprognostic (1.17e-1)" "unprognostic (3.62e-2)" "unprognostic (3.74e-1)" "unprognostic (5.23e-2)" "unprognostic (9.09e-2)" "unprognostic (6.07e-2)" "unprognostic (8.37e-2)" "unprognostic (2.16e-1)" "unprognostic (3.49e-1)" "unprognostic (1.41e-1)" "unprognostic (1.09e-2)" "unprognostic (7.62e-2)" "unprognostic (1.91e-1)" "unprognostic (1.14e-1)" "unprognostic (6.38e-3)" 2.7 2.2 1.1 0.7 1.5 0.0 1.1 5.1 8.5 2.8 0.0 3.3 0.2 1.2 2.3 1.0 5.2 1.3 0.4 1.0 3.9 0.2 1.2 0.7 0.2 5.0 3.8 11.1 0.5 1.3 4.9 0.0 4.9 15.7 0.9 0.3 0.3 5.3 0.3 0.6 0.3 0.6 4.4 0.4 2.0 0.8 0.9 0.0 3.3 0.0 0.0 4.2 0.9 3.6 0.0 0.0 0.3 0.1 0.0 0.0 0.0 51.3 29.4 33.1 22.6 0.2 0.1 0.0 0.1 148.4 1.3 0.0 0.4 0.0 8.8 0.0 3.3 0.0 9.1 0.1 1.3 0.0 0.0 1.4 2.2 0.0 0.1 0.0 0.0 3.3 0.0 6.3 0.8 0.0 0.2 0.0 0.7 0.0 4.3 0.0 0.7 0.0 0.0 0.0 0.5 0.0 21.4 0.0 0.0 0.2 3.6 0.0 0.0 0.0 3.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.5 5.1 8.5 1.0 3.9 5.0 3.8 4.9 4.4 0.9 3.6 0.0 0.0 1.9 4.6 0.1 0.0 0.0 0.2 0.6 0.3 0.0 0.1 1.9 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.5 0.1 0.1 0.0 0.0 39.1 0.2 0.0 2.2 0.0 0.1 0.0 11.1 0.0 0.8 0.0 0.0 15.7 0.0 0.0 0.0 0.8 2.1 0.0 0.0 0.0 3.7 0.0 0.2 0.0 0.5 1.2 0.1 0.0 7.2 0.1 0.1 0.0 0.1 7.3 0.1 0.0 0.0 1.0 0.1 0.3 0.1 0.0 0.0 0.0 0.4 0.0 0.0 MNS1 "FLJ11222, SPATA40" ENSG00000138587 "Meiosis specific nuclear structural 1" Q8NEH6 15 56421544-56465137 "Human disease related genes, Predicted intracellular proteins" Meiosis "Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 21.2;testis: 48.2" "Group enriched" "Detected in many" 5 "Early spermatids: 504.6;Endometrial ciliated cells: 256.5;Respiratory ciliated cells: 232.5;Spermatocytes: 249.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039975, HPA040382" Uncertain Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Nuclear speckles" "HPA039975: AB_10793858, HPA040382: AB_10794740" "unprognostic (7.78e-2)" "unprognostic (2.54e-2)" "unprognostic (1.19e-1)" "unprognostic (5.07e-2)" "unprognostic (2.25e-1)" "unprognostic (6.62e-2)" "unprognostic (1.15e-1)" "unprognostic (3.45e-2)" "unprognostic (1.13e-2)" "unprognostic (2.05e-2)" "unprognostic (6.63e-2)" "unprognostic (1.06e-1)" "unprognostic (1.12e-3)" "unprognostic (8.20e-3)" "unprognostic (1.15e-1)" "unprognostic (2.72e-2)" "unprognostic (7.71e-2)" 1.9 1.4 2.6 1.6 2.4 4.6 3.1 10.1 2.9 3.5 12.3 1.9 2.3 3.6 1.3 2.7 21.2 3.3 2.5 2.2 2.4 10.5 1.9 3.4 1.3 7.2 6.8 4.0 2.4 0.6 3.5 1.6 5.1 2.3 2.0 4.7 2.0 1.7 1.0 1.4 2.1 1.3 6.1 1.4 2.2 48.2 2.7 5.6 2.9 1.1 1.2 1.3 2.5 3.9 32.1 7.4 3.8 11.3 3.1 6.7 0.7 7.6 4.4 8.8 18.6 10.5 15.0 17.8 9.4 3.2 12.8 12.3 4.7 4.4 17.9 0.0 1.9 22.9 8.8 1.8 1.1 7.9 2.4 2.7 0.2 17.9 2.6 3.7 1.6 6.8 5.2 0.0 7.6 4.2 0.3 9.8 1.2 16.4 4.3 15.0 22.6 0.2 8.7 6.1 29.5 8.9 12.7 3.8 13.6 0.9 9.1 12.1 0.7 12.0 13.6 11.6 18.8 3.6 11.9 0.3 13.4 18.3 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 2.4 10.1 2.9 2.2 2.4 7.2 6.8 5.1 6.1 2.7 3.9 0.7 0.0 4.7 1.0 0.8 3.3 8.8 9.3 1.8 10.5 4.7 8.3 6.0 4.3 28.3 35.0 25.0 1.8 0.2 3.7 11.7 10.9 504.6 256.5 7.8 2.0 1.2 3.0 4.9 1.9 3.9 14.0 5.1 7.2 0.0 11.0 6.8 0.4 7.0 15.2 3.7 4.5 10.2 1.0 5.5 60.8 12.8 2.0 0.0 0.0 0.8 12.4 0.0 1.5 2.8 1.2 0.1 8.6 0.5 3.0 0.3 12.3 232.5 32.6 0.0 21.6 6.5 249.6 25.0 7.1 1.4 0.5 1.0 6.4 6.0 3.5 MOCS2 "MOCO1, MOCS2A, MOCS2B" ENSG00000164172 "Molybdenum cofactor synthesis 2" "O96007, O96033" 5 53095679-53110063 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 573.2;Proximal tubular cells: 281.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037679, HPA037680" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "Nucleoplasm, Nuclear speckles" "HPA037679: AB_2675604, HPA037680: AB_10673635" "unprognostic (3.27e-1)" "unprognostic (3.11e-2)" "unprognostic (2.82e-1)" "unprognostic (8.37e-3)" "unprognostic (2.12e-1)" "unprognostic (3.48e-2)" "unprognostic (1.60e-2)" "unprognostic (1.33e-1)" "unprognostic (6.66e-2)" "unprognostic (7.59e-2)" "unprognostic (2.41e-3)" "unprognostic (1.85e-1)" "prognostic favorable (3.68e-6)" "unprognostic (1.04e-1)" "unprognostic (1.04e-2)" "unprognostic (2.04e-1)" "unprognostic (5.86e-2)" 48.7 79.4 79.1 24.9 84.9 9.1 42.1 80.3 107.6 34.7 74.4 41.9 40.8 30.0 45.9 35.2 26.5 31.3 87.0 84.3 86.3 114.8 126.2 28.2 26.1 79.2 80.5 43.5 42.4 89.6 30.5 35.9 82.4 36.8 32.3 59.3 48.9 44.9 109.3 16.6 40.2 34.4 85.6 23.6 37.2 26.0 88.0 28.3 55.4 111.8 25.2 30.8 24.6 87.4 79.4 62.7 42.9 109.9 85.0 83.2 51.6 99.5 91.9 74.4 89.8 79.7 56.5 76.7 143.5 69.9 127.1 45.0 91.7 96.7 117.2 19.6 84.8 61.7 58.2 75.9 94.4 65.0 43.0 65.1 41.7 91.7 83.5 81.0 85.1 101.4 58.7 44.2 129.5 115.5 72.7 31.8 37.0 34.2 130.1 36.0 93.0 67.0 144.1 56.6 29.4 33.7 69.4 57.3 72.9 56.9 107.2 15.4 55.6 76.9 81.0 69.1 120.5 49.4 84.8 91.5 106.7 16.8 125.1 14.5 21.8 15.6 36.9 26.9 46.2 37.5 42.7 42.8 29.8 40.5 55.3 49.2 3.8 43.5 25.4 27.8 44.9 28.9 79.1 84.9 80.3 107.6 84.3 86.3 79.2 80.5 82.4 85.6 88.0 87.4 51.7 54.5 29.7 14.4 23.5 13.4 40.1 48.5 19.9 30.2 55.7 50.5 122.9 62.9 37.9 69.9 27.1 95.4 19.4 18.2 573.2 43.7 7.3 22.6 29.0 37.6 26.4 18.7 19.1 43.7 37.3 55.7 19.9 26.8 10.1 38.8 26.0 132.6 41.3 6.7 18.4 22.7 44.7 31.2 20.1 14.6 50.7 28.7 23.2 6.5 12.2 67.5 29.9 4.5 11.9 22.1 18.2 68.8 26.7 34.5 65.7 281.7 32.9 21.7 32.9 73.8 49.4 46.7 62.9 37.5 15.6 32.3 25.8 64.2 30.9 34.5 MORF4L1 "Eaf3, HsT17725, MEAF3, MORFRG15, MRG15" ENSG00000185787 "Mortality factor 4 like 1" Q9UBU8 15 78810487-78898139 "Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Growth regulation, Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042360, HPA062010" Approved Supported "Nuclear speckles" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 23: Testis - Cell cycle regulation" "Cluster 12: NES - Nervous system development" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" "HPA042360: AB_10794275, HPA062010: AB_2684655" "unprognostic (5.36e-2)" "unprognostic (4.30e-1)" "unprognostic (3.68e-1)" "unprognostic (9.69e-2)" "unprognostic (1.27e-1)" "unprognostic (1.83e-3)" "unprognostic (3.61e-3)" "unprognostic (8.61e-3)" "unprognostic (3.15e-1)" "unprognostic (3.58e-2)" "unprognostic (6.96e-2)" "unprognostic (3.69e-1)" "unprognostic (5.77e-2)" "unprognostic (1.17e-1)" "unprognostic (2.12e-1)" "unprognostic (3.92e-2)" "unprognostic (2.60e-3)" 272.8 306.3 183.9 237.6 193.6 427.6 241.5 197.6 285.5 283.8 188.9 270.1 169.4 305.1 213.0 201.1 257.9 256.5 396.6 187.9 240.5 332.2 258.9 243.4 251.8 232.8 221.6 318.2 165.5 263.6 175.1 300.9 223.4 228.7 225.7 265.5 195.9 282.7 559.3 140.5 187.4 331.5 205.4 217.4 186.9 588.7 220.1 297.6 270.2 425.2 279.6 266.2 184.3 227.9 362.0 480.3 863.5 355.4 603.2 620.4 453.2 644.3 636.0 570.7 554.0 436.9 532.7 446.7 517.2 649.1 376.0 442.1 1054.3 432.8 534.3 446.0 420.3 493.5 483.5 406.5 617.9 410.4 424.3 436.7 482.5 323.1 447.6 550.1 689.1 309.7 526.3 398.2 659.2 335.3 392.9 301.6 930.7 472.9 208.5 431.8 673.0 431.0 459.2 488.1 443.6 457.7 578.1 367.2 825.7 871.1 441.7 533.9 543.1 667.2 471.6 359.0 549.6 256.4 770.6 499.2 412.3 647.4 501.4 118.5 195.0 197.5 123.0 188.4 149.4 172.7 176.9 141.6 225.5 163.7 241.9 174.2 154.9 145.1 155.8 214.4 214.2 318.6 183.9 193.6 197.6 285.5 187.9 240.5 232.8 221.6 223.4 205.4 220.1 227.9 374.2 301.3 249.0 38.2 300.0 418.1 624.1 724.2 256.6 104.5 236.1 198.9 372.2 286.0 512.3 290.6 62.6 611.9 309.4 173.4 686.7 545.5 740.6 377.8 352.6 391.1 275.2 298.0 69.6 312.8 815.0 468.2 153.4 282.5 465.8 179.5 372.3 328.6 379.1 200.2 68.5 263.6 451.6 310.9 601.3 504.6 389.5 325.7 501.6 52.5 450.8 322.0 306.9 40.2 80.0 407.4 185.5 464.9 232.0 489.8 178.6 805.1 582.5 97.5 315.5 368.3 500.6 1322.3 467.9 185.3 370.4 663.0 338.2 279.9 199.0 597.1 MRTFB "FLJ31823, MKL2, MRTF-B" ENSG00000186260 "Myocardin related transcription factor B" Q9ULH7 16 14071319-14266773 "Disease related genes, Predicted intracellular proteins" "Differentiation, Myogenesis, Transcription, Transcription regulation" "Activator, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 43.9;Cardiomyocytes: 26.9;Cytotrophoblasts: 9.9;Endothelial cells: 9.6;Extravillous trophoblasts: 10.0;Smooth muscle cells: 14.9;Syncytiotrophoblasts: 10.4" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 170 "amygdala: 9.4;basal ganglia: 15.1;cerebral cortex: 21.4;hippocampal formation: 21.7" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011286 Enhanced Supported "Nuclear speckles" NA NA "Cluster 30: Non-specific - Translation" "Cluster 46: Fibroblasts - ECM organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nuclear speckles" "HPA011286: AB_1853973" "unprognostic (2.00e-1)" "unprognostic (5.28e-1)" "unprognostic (1.30e-2)" "unprognostic (3.62e-1)" "unprognostic (7.16e-2)" "unprognostic (7.14e-3)" "unprognostic (1.21e-1)" "unprognostic (1.37e-1)" "unprognostic (1.41e-1)" "unprognostic (2.38e-1)" "unprognostic (3.19e-1)" "unprognostic (2.32e-1)" "prognostic favorable (6.20e-4)" "unprognostic (5.22e-2)" "unprognostic (3.55e-1)" "unprognostic (2.47e-2)" "unprognostic (5.96e-2)" 21.4 7.3 9.4 8.6 15.1 3.8 18.3 0.0 21.4 19.0 0.0 9.9 9.7 14.9 9.1 14.5 14.0 13.3 11.8 21.7 0.0 8.4 5.9 13.2 7.6 0.0 0.0 7.1 12.1 22.2 4.9 21.7 0.0 15.5 10.8 8.6 11.6 15.2 11.9 16.6 7.9 15.6 0.0 5.1 10.1 17.5 0.0 10.3 16.9 14.5 8.1 11.3 12.2 0.0 17.6 17.8 17.8 13.2 5.9 11.0 8.0 4.9 13.3 7.4 10.6 7.7 16.4 9.4 12.4 8.4 9.3 13.8 12.9 14.4 13.5 23.1 7.0 6.0 13.6 13.3 8.2 4.2 5.4 8.4 14.6 12.8 8.3 7.8 14.7 12.2 7.9 9.7 5.6 15.1 13.4 2.8 6.0 4.7 4.8 20.5 13.7 8.1 7.3 17.3 6.2 10.8 23.9 10.2 4.9 8.2 18.0 3.5 9.4 15.3 14.9 4.4 6.4 6.6 8.8 8.4 16.6 7.1 11.7 0.2 0.5 0.0 1.1 0.7 1.7 3.7 1.9 0.9 0.7 1.5 2.4 1.3 0.3 1.1 0.8 1.7 0.9 0.6 9.4 15.1 0.0 21.4 21.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.9 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.9 0.0 0.0 0.0 0.0 9.9 1.5 0.0 0.0 0.0 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 10.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.9 0.0 0.0 0.0 0.0 10.4 0.4 0.0 0.0 0.0 MSX2 "CRS2, FPP, HOX8, MSH, PFM, PFM1" ENSG00000120149 "Msh homeobox 2" P35548 5 174724582-174730896 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Osteogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 25.8;placenta: 33.6;urinary bladder: 17.5" "Group enriched" "Detected in many" 6 "Cytotrophoblasts: 162.6;Endometrial ciliated cells: 65.7;Glandular and luminal cells: 62.2;Syncytiotrophoblasts: 233.8" "Cancer enhanced" "Detected in many" "endometrial cancer: 18.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "BEWO: 322.0" "Region enriched" "Detected in some" 5 "cerebellum: 6.2" "Low region specificity" "Detected in many" HPA005652 Uncertain Supported "Nuclear speckles" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nuclear speckles" "HPA005652: AB_1079418" "unprognostic (1.29e-1)" "unprognostic (1.08e-1)" "unprognostic (1.84e-1)" "prognostic favorable (8.43e-5)" "unprognostic (2.50e-2)" "unprognostic (1.22e-2)" "unprognostic (3.13e-1)" "prognostic unfavorable (6.93e-4)" "unprognostic (2.08e-2)" "unprognostic (1.60e-1)" "unprognostic (2.51e-2)" "unprognostic (7.26e-2)" "unprognostic (1.36e-4)" "unprognostic (7.64e-3)" "unprognostic (5.06e-2)" "unprognostic (2.12e-6)" "unprognostic (1.43e-2)" 2.1 0.3 0.7 0.5 1.0 0.0 8.1 4.3 1.1 2.7 1.1 0.9 0.3 6.8 0.0 0.6 0.9 0.9 1.6 1.2 1.4 0.3 0.0 0.8 0.1 7.8 1.3 0.2 0.4 25.8 0.3 33.6 4.1 2.5 0.1 0.0 0.8 0.8 1.9 6.9 0.8 1.4 5.4 0.8 2.8 5.6 1.3 0.1 0.7 1.8 0.1 17.5 1.8 5.4 0.4 4.0 1.1 3.2 0.0 0.0 322.0 2.2 3.6 0.7 0.1 56.6 23.0 0.0 8.6 0.2 19.6 6.2 17.6 6.4 0.2 0.0 10.7 0.0 1.4 0.0 2.4 0.0 3.0 3.7 4.5 3.1 3.5 0.0 0.0 0.0 0.0 0.0 5.0 27.7 0.0 0.4 2.5 38.3 8.5 0.0 8.8 0.1 4.0 35.3 0.0 2.5 0.0 43.0 2.9 69.6 25.7 0.2 0.0 1.1 5.5 17.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.0 4.3 1.1 1.2 1.4 7.8 1.3 4.1 5.4 1.3 5.4 1.5 0.0 0.0 2.3 0.0 9.6 2.4 0.1 3.4 0.2 15.8 18.9 1.7 0.0 0.1 0.0 0.0 162.6 0.2 0.3 0.0 0.6 0.2 65.7 4.9 0.7 0.0 0.0 0.0 0.0 13.9 5.3 5.1 62.2 4.5 0.1 0.4 0.0 11.3 0.0 0.0 1.9 0.0 0.6 2.9 0.6 0.0 1.0 1.8 0.0 0.0 1.6 0.0 0.0 0.0 1.0 0.0 0.0 0.1 2.3 1.9 0.1 0.1 0.0 0.0 8.9 4.8 1.4 4.5 2.0 11.4 233.8 1.0 0.6 1.2 9.8 MYADM ENSG00000179820 "Myeloid associated differentiation marker" Q96S97 19 53864763-53876435 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 207.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056301 Approved "Nuclear speckles" NA NA 27000 "Cluster 52: Eosinophils - Transcription" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles" "HPA056301: " "unprognostic (5.17e-2)" "unprognostic (1.41e-1)" "unprognostic (1.85e-1)" "unprognostic (2.94e-1)" "unprognostic (6.41e-2)" "unprognostic (1.01e-2)" "unprognostic (8.21e-3)" "prognostic unfavorable (8.15e-4)" "unprognostic (3.97e-2)" "unprognostic (1.29e-1)" "unprognostic (2.52e-1)" "unprognostic (4.11e-1)" "prognostic unfavorable (7.71e-7)" "unprognostic (2.28e-3)" "unprognostic (1.29e-1)" "unprognostic (2.37e-2)" "unprognostic (6.14e-3)" 179.4 25.7 21.5 66.5 20.2 196.3 82.4 3.1 21.6 97.4 24.6 155.6 48.9 248.6 22.2 76.8 146.5 124.6 92.3 16.7 22.2 19.8 46.4 110.7 37.2 16.9 24.7 73.4 101.1 31.1 17.9 89.6 13.7 75.0 39.9 3.6 48.8 100.9 36.7 45.2 63.8 180.9 6.4 42.5 79.5 28.4 17.3 37.1 57.8 21.1 15.2 104.6 64.8 18.8 28.8 231.6 29.2 23.3 96.2 66.0 45.3 145.9 105.9 57.0 58.7 94.4 84.1 2.6 53.7 187.4 61.6 56.4 14.6 56.7 48.5 34.9 34.2 38.0 35.8 75.6 219.2 78.4 131.3 72.3 12.7 73.4 10.5 93.4 52.0 14.9 41.5 68.7 36.4 32.0 21.4 60.9 27.9 104.3 65.3 82.1 31.0 13.3 63.8 3.0 0.4 43.8 1.2 44.6 14.1 58.4 44.4 66.8 105.5 125.8 44.5 17.0 66.2 44.7 29.9 0.6 78.4 37.1 2.1 74.3 48.1 165.5 20.9 27.1 19.6 5.4 13.4 15.2 59.5 7.1 12.5 11.0 207.4 17.8 23.5 22.3 5.4 20.0 21.5 20.2 3.1 21.6 16.7 22.2 16.9 24.7 13.7 6.4 17.3 18.8 125.9 163.5 59.1 2.9 138.9 103.0 173.3 73.1 96.8 4.1 141.0 105.8 67.1 97.2 91.5 20.2 4.2 46.2 143.3 43.8 0.0 106.6 2.7 97.0 164.1 117.2 202.4 35.7 9.1 51.8 243.9 279.7 83.1 195.5 347.6 27.0 182.8 18.5 73.5 10.1 8.3 203.9 24.4 120.4 217.2 2.2 90.1 180.3 60.5 11.2 68.0 4.0 19.6 7.1 13.9 71.4 54.7 116.6 189.9 56.6 2.7 0.5 57.0 1.4 151.2 340.1 199.0 35.9 14.5 19.7 59.8 49.5 221.5 20.5 93.8 75.0 NAMPT "PBEF, PBEF1" ENSG00000105835 "Nicotinamide phosphoribosyltransferase" P43490 7 106248298-106285966 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Biological rhythms, Pyridine nucleotide biosynthesis" "Cytokine, Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 580.0;Langerhans cells: 1123.7;Macrophages: 947.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 7 "neutrophil: 279.2" "Lineage enriched" "Detected in all" 9 "granulocytes: 279.2" "Cell line enhanced" "Detected in all" "HHSteC: 387.5;U-87 MG: 434.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034349, HPA047776, HPA057722" Approved Approved "Nuclear speckles,Cell Junctions" "Secreted to blood" NA NA 2140000 1400000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 41: Macrophages - Immune response" "Nuclear speckles" "Cell Junctions" "CAB034349: AB_2251220, HPA047776: AB_2680151, HPA057722: " "unprognostic (2.87e-1)" "prognostic unfavorable (4.78e-4)" "unprognostic (5.90e-3)" "unprognostic (1.63e-2)" "unprognostic (1.50e-2)" "prognostic unfavorable (8.81e-4)" "unprognostic (2.15e-1)" "unprognostic (2.74e-2)" "unprognostic (2.74e-1)" "unprognostic (3.30e-1)" "prognostic unfavorable (1.51e-4)" "unprognostic (3.02e-1)" "prognostic unfavorable (2.49e-6)" "unprognostic (6.83e-2)" "unprognostic (6.96e-2)" "unprognostic (7.76e-2)" "unprognostic (6.44e-3)" 308.5 74.2 14.4 360.5 15.6 312.5 103.3 15.2 35.4 47.3 21.7 62.5 38.5 38.6 6.9 228.2 107.6 113.7 103.1 15.2 20.9 82.9 317.9 218.5 23.2 75.7 24.9 58.4 80.9 25.9 30.1 87.3 30.3 70.1 30.3 17.2 126.0 13.4 135.9 54.1 55.9 48.0 21.3 88.2 102.4 11.7 46.3 15.6 42.2 44.4 39.9 283.3 86.7 21.5 103.6 41.0 14.6 16.8 85.8 95.0 34.4 26.1 194.7 57.0 90.6 25.7 38.7 77.7 78.8 32.1 131.5 58.2 38.8 88.1 93.8 50.5 51.7 35.8 17.2 22.6 387.5 61.3 49.4 94.8 94.2 114.9 115.0 70.6 187.3 32.0 70.5 225.6 68.1 49.4 58.1 19.4 36.6 33.6 59.7 25.8 30.4 147.6 46.2 60.8 33.4 19.3 46.0 61.1 107.9 43.0 25.4 9.4 168.2 75.6 52.9 105.9 51.9 212.1 142.7 115.7 434.3 69.3 105.6 39.6 6.5 16.0 1.8 21.8 2.4 3.9 2.2 2.7 7.0 3.4 2.8 2.2 279.2 4.4 30.5 5.5 7.1 4.8 14.4 15.6 15.2 35.4 15.2 20.9 75.7 24.9 30.3 21.3 46.3 21.5 323.8 131.4 245.7 12.1 78.0 207.6 321.0 105.7 169.0 23.8 184.2 132.0 94.8 197.3 161.4 42.3 12.5 26.2 67.5 105.8 46.9 320.6 12.2 128.0 160.8 192.8 25.1 29.5 25.3 141.3 58.9 239.6 132.0 296.5 188.4 18.8 159.5 580.0 107.0 40.4 28.8 51.9 63.1 390.3 1123.7 6.9 40.4 947.3 161.9 46.9 102.7 22.6 9.2 12.1 22.4 138.1 49.7 31.2 93.7 364.0 112.8 50.7 94.1 30.8 26.3 264.6 185.6 30.5 65.8 98.3 207.8 25.3 110.3 38.4 79.4 334.5 NCAPG2 "CAP-G2, FLJ20311, hCAP-G2, LUZP5, MTB" ENSG00000146918 "Non-SMC condensin II complex subunit G2" Q86XI2 7 158631169-158704804 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 24.4;lymphoid tissue: 27.9" "Cell type enhanced" "Detected in many" "Spermatocytes: 48.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026631, HPA049637" Approved Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear speckles" "HPA026631: AB_1845983, HPA049637: " "unprognostic (2.73e-2)" "unprognostic (1.77e-1)" "unprognostic (6.81e-2)" "prognostic unfavorable (7.94e-4)" "unprognostic (1.66e-1)" "prognostic favorable (1.91e-4)" "prognostic unfavorable (3.00e-5)" "unprognostic (5.33e-3)" "prognostic unfavorable (3.21e-4)" "unprognostic (7.79e-2)" "prognostic unfavorable (8.50e-4)" "unprognostic (5.19e-2)" "prognostic unfavorable (4.06e-5)" "unprognostic (2.58e-3)" "unprognostic (1.28e-1)" "unprognostic (8.21e-2)" "unprognostic (7.37e-2)" 3.7 2.5 2.0 8.8 2.2 24.4 5.4 2.5 2.1 4.0 1.3 6.9 4.4 4.3 2.1 6.9 3.0 2.9 2.9 2.2 2.1 2.6 4.1 3.1 12.4 2.0 1.7 3.1 2.2 4.6 3.5 5.9 2.1 2.8 7.6 2.8 3.5 2.8 3.4 6.8 5.8 4.8 1.6 4.6 5.6 14.8 1.8 27.9 3.2 4.1 13.8 4.0 3.9 2.4 103.9 53.7 64.1 41.8 9.5 15.4 25.3 74.3 47.4 89.0 99.0 48.5 52.0 64.0 45.0 30.3 95.1 51.7 53.7 33.8 117.2 68.4 40.4 57.2 64.8 38.8 4.2 72.2 62.3 6.8 3.7 73.1 21.0 16.2 50.4 72.9 71.9 91.6 82.8 111.4 119.2 48.8 63.7 58.8 43.3 69.7 67.8 60.6 22.6 45.9 69.6 54.5 91.6 35.0 20.2 40.4 31.4 46.5 25.9 60.6 45.9 166.2 120.6 61.3 48.2 77.2 64.6 89.6 118.5 5.9 0.9 1.1 5.2 1.2 7.5 1.6 5.2 3.6 2.3 1.0 1.6 1.8 0.7 5.2 5.1 1.1 7.2 2.2 2.0 2.2 2.5 2.1 2.2 2.1 2.0 1.7 2.1 1.6 1.8 2.4 3.6 6.4 1.5 3.9 4.1 4.0 2.1 2.8 1.8 3.9 3.7 3.3 4.8 2.8 4.6 1.8 0.0 6.7 5.1 3.4 0.0 2.3 15.1 4.0 4.6 4.3 0.0 19.6 10.7 3.3 10.4 4.5 4.1 5.9 1.3 12.6 2.9 2.6 7.3 8.4 7.2 2.9 2.0 3.8 5.2 7.2 2.8 4.4 1.8 3.7 2.7 2.1 2.1 10.1 10.7 2.3 0.4 4.1 11.0 1.1 0.3 1.3 6.0 2.8 6.6 4.3 5.7 48.2 18.5 6.1 2.0 2.6 4.9 5.0 5.7 3.0 NCBP3 "C17orf85, ELG, HSA277841" ENSG00000074356 "Nuclear cap binding subunit 3" Q53F19 17 3802158-3846246 "Predicted intracellular proteins" "Antiviral defense, mRNA capping, mRNA processing, mRNA transport, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008959, HPA013195" Supported Approved "Nuclear speckles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 14: REH - Unknown function" "Cluster 59: Non-specific - Transcription" "Nuclear speckles" "HPA008959: AB_2668184, HPA013195: AB_2668800" "unprognostic (1.39e-1)" "unprognostic (1.42e-1)" "unprognostic (2.11e-1)" "unprognostic (3.49e-3)" "unprognostic (1.97e-2)" "unprognostic (5.47e-2)" "unprognostic (2.53e-1)" "unprognostic (2.06e-2)" "prognostic unfavorable (4.68e-4)" "unprognostic (1.23e-1)" "unprognostic (1.84e-3)" "prognostic unfavorable (4.90e-4)" "unprognostic (2.00e-1)" "unprognostic (1.32e-1)" "unprognostic (3.64e-1)" "unprognostic (5.68e-2)" "unprognostic (5.36e-2)" 9.4 8.2 8.1 7.9 10.2 17.1 8.8 8.8 9.6 11.3 7.7 10.0 8.4 8.3 3.5 9.6 10.7 4.9 9.4 8.5 9.2 8.5 6.9 8.1 6.5 8.7 9.7 10.8 12.0 5.8 6.8 7.1 9.7 8.5 5.8 10.4 9.4 4.3 8.8 11.8 10.3 5.8 8.6 10.8 9.4 16.8 9.1 13.9 8.4 3.3 5.4 9.5 9.4 15.2 12.4 15.8 14.3 10.6 7.3 5.3 7.0 8.3 5.6 11.4 7.2 6.3 4.7 10.9 7.3 8.8 5.4 22.2 10.8 10.9 14.5 13.6 14.9 8.9 7.7 7.0 6.1 5.4 12.6 8.2 4.6 10.9 11.5 9.1 9.6 16.0 11.2 11.1 8.5 4.1 19.7 9.6 13.1 5.6 5.9 33.8 11.3 7.1 5.9 6.3 5.2 11.2 17.4 5.9 11.9 11.6 9.1 11.2 9.8 6.5 8.9 10.3 18.2 5.9 6.0 9.3 8.3 9.6 10.3 0.9 2.0 2.6 2.2 1.3 1.9 1.7 1.8 3.0 1.3 1.1 3.0 2.5 2.8 1.4 0.8 2.1 3.2 1.2 8.1 10.2 8.8 9.6 8.5 9.2 8.7 9.7 9.7 8.6 9.1 15.2 45.1 51.3 41.2 0.0 31.2 0.0 26.8 0.0 26.2 44.8 32.2 27.3 0.0 22.8 24.1 25.8 35.5 93.6 59.5 13.1 13.7 24.8 13.5 49.8 63.2 27.8 10.9 21.7 0.0 23.5 21.0 31.1 29.6 48.2 24.0 56.7 29.6 21.5 23.3 33.7 0.0 16.6 0.0 29.9 0.0 17.0 24.8 28.3 0.0 0.0 36.7 20.9 46.4 0.0 0.0 26.8 16.9 18.8 37.7 28.6 20.3 18.2 35.0 45.4 32.9 42.4 27.8 48.0 50.6 30.9 0.0 99.3 34.3 34.1 19.4 28.4 NDUFB1 "CI-MNLL, MNLL" ENSG00000183648 "NADH:ubiquinone oxidoreductase subunit B1" O75438 14 92116122-92121917 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 2435.4;Hepatocytes: 1690.0;Proximal tubular cells: 1614.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063737 Supported Supported "Nuclear speckles,Mitochondria" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "Nuclear speckles" "HPA063737: AB_2685109" "unprognostic (1.12e-2)" "unprognostic (1.31e-3)" "unprognostic (6.70e-2)" "unprognostic (2.67e-2)" "unprognostic (1.28e-1)" "unprognostic (2.54e-2)" "unprognostic (6.91e-2)" "unprognostic (3.74e-3)" "unprognostic (5.35e-3)" "unprognostic (4.55e-3)" "unprognostic (1.18e-2)" "unprognostic (4.15e-2)" "prognostic favorable (1.31e-5)" "unprognostic (7.35e-2)" "unprognostic (1.19e-1)" "unprognostic (2.16e-1)" "unprognostic (5.05e-3)" 260.8 396.4 370.4 109.0 381.4 167.4 231.8 388.5 588.6 178.3 409.2 313.4 165.7 164.9 178.3 281.5 177.1 61.2 1221.5 381.0 401.1 512.7 503.2 182.3 118.4 379.8 374.6 162.7 206.3 373.5 314.7 61.1 383.2 221.5 122.4 260.9 233.5 59.5 862.6 153.6 225.9 69.4 381.2 214.0 292.4 112.3 376.4 230.6 250.4 1053.8 106.1 192.1 202.4 391.0 198.3 388.3 332.5 208.4 219.1 160.7 143.0 243.2 143.7 147.5 135.4 236.9 341.0 187.0 215.7 151.3 205.8 249.6 198.4 212.3 133.9 280.8 425.1 361.3 665.8 308.5 178.2 290.4 196.4 202.5 132.0 159.5 140.7 334.8 136.7 353.7 199.0 370.1 211.8 759.0 286.6 250.0 166.4 779.6 492.1 253.3 309.7 274.2 397.7 491.3 210.8 152.8 486.6 289.7 338.3 277.7 432.0 435.0 291.8 89.3 173.0 181.3 161.7 288.4 477.2 422.0 278.4 208.5 187.9 456.1 566.8 447.5 247.4 409.6 288.5 373.7 361.5 286.0 508.6 306.8 355.4 343.9 721.3 296.6 386.6 604.6 438.9 653.6 370.4 381.4 388.5 588.6 381.0 401.1 379.8 374.6 383.2 381.2 376.4 391.0 158.5 166.7 227.4 11.4 187.4 128.7 102.1 334.5 96.8 84.6 328.2 353.6 2435.4 467.5 237.0 389.9 39.6 260.3 170.4 627.2 1166.1 245.4 175.8 326.0 208.6 188.2 317.4 256.1 18.4 427.7 118.8 203.6 189.6 225.8 215.8 96.2 397.3 1690.0 422.3 55.5 21.7 515.9 268.5 619.8 179.3 57.3 262.5 281.7 332.6 10.3 478.1 223.3 241.0 11.1 15.0 294.4 628.7 241.1 201.6 97.9 845.2 1614.3 337.6 183.3 223.5 172.4 188.2 138.8 151.5 204.5 176.2 205.8 163.7 97.4 540.6 116.3 NEK8 NPHP9 ENSG00000160602 "NIMA related kinase 8" Q86SG6 17 28725897-28743455 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Ciliopathy, Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 14.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA040661, HPA040679" Approved Approved "Nuclear speckles,Microtubules,Mitotic spindle" Yes NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 7: Kidney - Transmembrane transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Microtubules "Nuclear speckles, Mitotic spindle" "HPA040661: AB_10794065, HPA040679: AB_10796226" "unprognostic (2.63e-1)" "unprognostic (4.57e-2)" "prognostic unfavorable (6.98e-4)" "unprognostic (6.25e-2)" "unprognostic (2.23e-2)" "unprognostic (5.93e-3)" "unprognostic (6.48e-2)" "prognostic favorable (4.52e-4)" "unprognostic (7.85e-2)" "unprognostic (1.37e-1)" "unprognostic (1.51e-3)" "unprognostic (1.55e-1)" "unprognostic (4.87e-3)" "unprognostic (4.61e-2)" "unprognostic (3.58e-1)" "unprognostic (1.75e-1)" "unprognostic (4.67e-3)" 1.5 3.1 1.7 3.3 1.9 1.7 2.4 1.4 1.9 2.5 3.8 2.4 3.0 1.5 3.2 2.5 3.9 2.0 1.0 1.4 1.6 9.1 5.2 3.3 5.8 2.0 1.7 1.9 4.5 2.9 4.4 2.6 1.7 4.0 2.2 0.6 3.7 2.6 0.5 3.1 4.2 1.2 1.6 5.8 3.4 3.8 1.9 2.7 7.2 0.4 5.0 2.6 2.2 2.3 2.1 3.4 3.5 2.8 1.9 2.1 10.9 0.9 2.1 1.3 1.7 5.4 5.0 13.1 3.5 2.8 2.5 3.8 5.2 4.8 1.3 3.5 6.4 2.9 5.8 10.1 3.3 1.8 3.7 4.8 1.8 2.5 5.8 1.8 0.9 1.9 4.3 1.3 1.5 4.7 1.9 3.4 3.3 3.7 1.0 4.9 2.3 5.9 7.0 5.7 6.4 1.5 3.0 6.3 1.6 4.7 9.3 2.4 0.8 1.3 2.2 1.6 1.0 1.5 1.8 8.9 2.0 1.6 3.1 3.3 0.9 1.2 0.7 0.5 0.8 2.8 0.6 0.7 0.1 4.2 0.7 1.0 0.4 1.3 1.1 14.8 0.5 0.8 1.7 1.9 1.4 1.9 1.4 1.6 2.0 1.7 1.7 1.6 1.9 2.3 2.7 9.6 19.3 3.9 22.9 2.8 9.2 8.3 7.4 2.8 10.1 14.1 1.7 12.8 11.6 25.8 8.4 17.6 19.1 14.9 7.9 5.8 9.5 12.8 6.0 2.9 10.3 7.0 0.7 6.0 9.2 3.9 6.1 15.2 26.6 3.2 3.3 9.4 3.9 1.7 0.5 14.4 10.2 5.0 2.7 2.0 3.4 4.4 3.6 2.8 4.0 2.6 3.1 1.5 1.6 3.9 17.2 2.6 7.2 8.6 13.4 4.3 14.3 1.8 0.0 11.7 3.0 19.9 11.4 8.8 1.6 11.1 4.9 7.8 15.9 4.2 NEUROG3 "Atoh5, bHLHa7, Math4B, ngn3" ENSG00000122859 "Neurogenin 3" Q9Y4Z2 10 69571698-69573422 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "brain: 5.4;intestine: 2.6" "Group enriched" "Detected in some" 6 "Cardiomyocytes: 9.5;Enteroendocrine cells: 5.3" "Cancer enhanced" "Detected in some" "stomach cancer: 1.4" "Group enriched" "Detected in some" 20 "cerebral cortex: 4.5;hippocampal formation: 5.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "THP-1: 9.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA039785 Uncertain Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nuclear speckles" Nucleoplasm "HPA039785: AB_10795114" "unprognostic (1.22e-2)" "unprognostic (7.33e-2)" "unprognostic (3.04e-2)" "unprognostic (2.42e-1)" "unprognostic (1.10e-1)" "unprognostic (1.65e-2)" "unprognostic (5.85e-5)" "unprognostic (4.58e-2)" "unprognostic (4.19e-1)" 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 4.5 0.0 0.0 0.6 2.6 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 4.5 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 5.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 NFATC4 NFAT3 ENSG00000100968 "Nuclear factor of activated T cells 4" Q14934 14 24365673-24379604 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 58.8;Endometrial stromal cells: 28.3;Fibroblasts: 22.8;Sertoli cells: 26.3;Smooth muscle cells: 27.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 36.8;BJ hTERT+: 49.5;hTERT-RPE1: 42.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA031641, CAB032859, HPA076526" Uncertain Supported "Nuclear speckles,Cytosol" No No "Cluster 72: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nuclear speckles, Cytosol" "CAB032859: AB_1128521, HPA031641: AB_10600826, HPA076526: AB_2686805" "unprognostic (3.51e-1)" "unprognostic (5.61e-2)" "prognostic unfavorable (5.84e-4)" "unprognostic (8.08e-2)" "unprognostic (1.67e-1)" "unprognostic (6.57e-2)" "unprognostic (3.24e-2)" "unprognostic (1.15e-1)" "unprognostic (1.27e-1)" "unprognostic (4.18e-2)" "unprognostic (1.39e-1)" "unprognostic (9.11e-2)" "prognostic unfavorable (1.81e-6)" "unprognostic (1.47e-2)" "unprognostic (1.07e-1)" "unprognostic (1.35e-1)" "unprognostic (4.19e-2)" 48.4 54.9 9.1 6.0 9.4 0.6 47.2 8.6 10.5 126.0 9.0 71.9 4.5 82.1 13.7 22.2 82.6 17.8 30.2 9.0 9.3 35.5 5.6 30.2 4.8 10.3 9.4 142.7 13.8 9.0 37.9 18.2 8.8 51.5 5.0 2.8 20.5 16.2 9.0 25.0 29.9 18.8 8.2 17.7 35.5 42.7 9.7 1.7 50.4 2.5 3.6 66.2 65.9 8.5 0.0 0.1 17.8 0.0 25.4 36.8 0.1 17.3 49.5 23.0 20.0 0.0 14.6 14.9 0.5 25.0 1.6 0.0 7.1 0.3 13.9 0.0 0.6 11.3 20.6 0.0 12.3 0.0 0.0 26.8 0.3 13.9 0.1 42.5 18.2 4.7 3.7 0.0 4.5 0.8 0.0 1.7 2.3 1.0 0.1 1.1 1.6 2.0 0.0 0.2 2.9 11.9 0.0 3.3 5.7 8.7 10.3 4.5 10.3 21.3 4.4 20.5 0.0 10.4 1.6 11.0 4.4 0.0 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 9.4 8.6 10.5 9.0 9.3 10.3 9.4 8.8 8.2 9.7 8.5 4.1 3.2 8.1 58.8 1.1 4.5 0.9 1.9 0.6 1.3 3.3 2.8 7.8 0.0 4.8 0.0 0.0 0.6 0.0 0.8 0.0 2.8 4.4 2.5 28.3 4.6 7.7 0.0 0.1 0.2 0.6 22.8 3.6 6.4 0.0 4.1 1.4 0.2 0.6 0.0 0.2 3.4 10.2 0.0 6.8 6.5 17.4 0.4 7.2 13.1 0.0 7.6 0.0 1.0 0.2 0.6 0.3 7.5 0.2 0.8 0.4 0.2 2.1 1.5 26.3 4.3 27.1 12.5 2.9 1.0 3.4 0.5 0.9 6.0 1.6 2.3 NFKBIZ "FLJ34463, INAP, MAIL" ENSG00000144802 "NFKB inhibitor zeta" Q9BYH8 3 101827991-101861022 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "bone marrow: 406.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 33.9" "Group enriched" "Detected in many" 5 "granulocytes: 24.7;monocytes: 33.9" "Cell line enhanced" "Detected in many" "BJ hTERT+: 72.1;RPTEC TERT1: 71.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA010547, HPA075363" Enhanced Supported "Nuclear speckles,Cytoplasmic bodies" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 41: Macrophages - Immune response" "Nuclear speckles" "Cytoplasmic bodies" "HPA010547: AB_1854442, HPA075363: AB_2686745" "unprognostic (2.20e-2)" "unprognostic (1.11e-2)" "unprognostic (6.76e-2)" "unprognostic (1.91e-1)" "unprognostic (1.54e-2)" "unprognostic (1.68e-2)" "unprognostic (1.62e-2)" "unprognostic (1.62e-1)" "unprognostic (9.22e-2)" "unprognostic (5.96e-2)" "unprognostic (1.40e-1)" "unprognostic (8.82e-2)" "prognostic unfavorable (4.30e-8)" "unprognostic (2.69e-1)" "unprognostic (8.90e-2)" "unprognostic (3.30e-1)" "unprognostic (8.52e-3)" 57.5 12.0 2.8 44.4 5.2 406.0 31.7 4.7 6.0 13.4 19.1 24.5 52.6 36.3 3.7 26.9 64.8 51.3 23.6 3.4 4.8 29.2 52.4 48.2 27.2 6.7 4.2 19.1 27.0 3.6 12.5 22.3 5.5 26.6 30.6 8.0 80.8 7.4 4.6 45.7 23.2 54.6 6.2 26.9 30.5 3.7 6.8 18.8 24.7 10.2 22.7 71.3 18.3 5.0 6.5 5.2 3.5 4.4 9.7 16.7 5.3 26.2 72.1 11.3 10.7 6.3 7.8 12.2 32.4 7.2 34.8 20.5 2.5 11.4 29.2 35.9 2.3 11.7 10.2 3.4 14.7 0.8 0.7 11.6 17.3 30.5 13.7 27.8 8.4 0.3 2.0 24.6 16.2 8.1 0.2 6.9 6.0 2.3 15.3 1.5 15.7 1.5 71.0 42.7 1.5 1.9 4.4 5.3 29.6 7.4 6.3 4.8 10.6 18.1 18.0 6.9 8.6 20.4 7.8 8.1 32.9 2.2 2.5 11.7 5.9 1.7 1.4 13.1 1.7 2.9 2.1 1.6 3.8 4.6 6.0 4.2 24.7 0.8 33.9 6.0 1.3 2.3 2.8 5.2 4.7 6.0 3.4 4.8 6.7 4.2 5.5 6.2 6.8 5.0 199.5 86.6 266.6 10.7 91.3 281.7 61.2 123.0 103.0 9.0 108.7 105.8 20.6 84.4 143.0 66.2 2.1 19.3 98.6 157.8 0.0 213.0 4.6 116.1 221.4 135.3 73.6 21.0 23.7 132.1 41.0 214.2 277.8 291.9 381.8 17.9 82.1 65.2 56.5 10.1 20.2 69.7 59.0 150.6 291.5 1.3 20.2 318.4 71.2 16.9 79.0 25.7 12.3 17.1 79.3 127.6 115.8 0.7 128.5 88.8 91.2 5.6 117.3 8.9 19.7 218.4 131.1 0.6 2.6 136.4 251.7 25.6 134.0 19.2 111.7 70.5 NME8 "CILD6, NM23-H8, SPTRX2, TXNDC3" ENSG00000086288 "NME/NM23 family member 8" Q8N427 7 37848597-37900397 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Ciliopathy, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "bone marrow: 12.3;testis: 10.4" "Cell type enhanced" "Detected in some" "dendritic cells: 22.8;Early spermatids: 46.3;Late spermatids: 23.4;NK-cells: 17.5;Oligodendrocytes: 9.8;Spermatocytes: 26.5" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HMC-1: 1.2;NB-4: 2.0;NTERA-2: 1.7;THP-1: 1.7;U-937: 5.3" "Not detected" "Not detected" "Not detected" "Not detected" "CAB016416, HPA019259, HPA029572" Enhanced Supported "Nuclear speckles,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "Nuclear speckles" "CAB016416: , HPA019259: AB_1858475, HPA029572: " "unprognostic (7.44e-3)" "unprognostic (2.32e-2)" "unprognostic (9.11e-2)" "unprognostic (2.97e-2)" "unprognostic (6.05e-2)" "unprognostic (1.20e-2)" "unprognostic (6.56e-2)" "unprognostic (4.22e-2)" "unprognostic (7.17e-2)" "unprognostic (1.05e-1)" "unprognostic (3.24e-1)" "unprognostic (2.34e-2)" "unprognostic (8.13e-8)" "unprognostic (5.90e-2)" "unprognostic (3.36e-1)" "unprognostic (1.49e-1)" "unprognostic (1.86e-1)" 0.1 0.1 0.4 0.6 0.9 12.3 0.1 0.5 0.7 0.1 0.5 0.3 0.1 0.1 0.1 0.2 0.1 0.5 0.0 0.3 0.7 0.0 0.1 0.4 0.5 1.1 0.6 0.0 0.0 0.0 0.0 0.2 0.9 0.1 0.1 0.0 0.1 0.1 0.0 0.4 0.2 0.1 0.7 1.0 0.2 10.4 0.9 0.3 0.0 0.0 0.3 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 1.1 0.9 0.3 0.2 0.0 0.0 0.0 0.7 0.9 0.0 0.0 0.3 2.1 0.1 0.0 4.6 0.0 0.4 0.4 0.9 0.5 0.7 0.3 0.7 1.1 0.6 0.9 0.7 0.9 1.0 0.1 0.0 2.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.1 22.8 0.0 0.0 0.0 46.3 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 5.1 0.0 0.0 0.0 0.8 0.0 0.4 0.0 0.0 1.9 5.1 23.4 0.0 3.3 0.0 0.0 2.6 0.0 17.5 0.0 9.8 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 26.5 0.7 0.0 0.0 0.0 2.2 0.0 0.0 0.0 NONO "NMT55, NRB54, P54, P54NRB, PPP1R114" ENSG00000147140 "Non-POU domain containing octamer binding" Q15233 X 71254814-71301522 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, DNA damage, DNA recombination, DNA repair, Immunity, Innate immunity, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor, RNA-binding" "Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022069, HPA054094, HPA054559" Enhanced Enhanced "Nucleoplasm,Nucleoli fibrillar center,Nuclear speckles" NA NA 450000 "Cluster 44: Non-specific - Transcription" "Cluster 63: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Nucleoli fibrillar center, Nuclear speckles" "CAB022069: , HPA054094: AB_2682376, HPA054559: AB_2682522" "unprognostic (2.39e-3)" "unprognostic (2.22e-2)" "unprognostic (2.64e-1)" "prognostic unfavorable (9.29e-4)" "unprognostic (8.87e-2)" "unprognostic (5.54e-2)" "unprognostic (1.02e-3)" "unprognostic (9.34e-2)" "unprognostic (2.32e-2)" "unprognostic (1.41e-2)" "unprognostic (3.12e-1)" "unprognostic (2.07e-1)" "unprognostic (7.29e-3)" "unprognostic (6.79e-2)" "unprognostic (5.73e-3)" "unprognostic (2.76e-2)" "unprognostic (3.04e-2)" 106.4 147.2 58.6 96.4 57.7 115.3 109.2 71.5 64.9 116.8 64.4 101.3 86.2 130.2 107.9 111.9 115.4 100.7 81.2 55.3 69.9 103.3 121.5 103.2 136.5 60.3 61.5 197.9 164.8 114.8 97.1 99.1 60.5 97.0 101.2 70.2 106.8 89.6 99.1 112.2 102.0 113.5 59.2 109.5 114.3 55.2 68.5 255.5 116.0 86.1 165.2 116.8 102.6 61.0 421.2 539.7 595.3 344.4 251.2 238.5 345.3 330.9 319.2 459.3 388.5 413.4 312.9 481.4 379.9 320.5 309.7 310.5 949.5 299.4 488.1 383.9 605.7 394.8 498.4 398.0 212.3 547.7 338.7 272.0 206.0 473.1 305.7 370.5 382.0 342.1 535.3 509.0 406.2 413.9 756.0 466.8 771.3 433.9 365.2 660.0 657.3 414.0 345.9 426.1 431.7 519.4 467.8 299.1 392.5 354.9 271.4 354.0 343.9 268.0 438.6 402.9 400.1 297.3 503.2 516.0 216.8 627.1 433.8 107.5 117.3 91.1 107.9 120.0 119.9 107.4 107.9 106.4 118.7 107.2 115.1 115.6 50.8 119.6 140.7 101.1 128.0 178.1 58.6 57.7 71.5 64.9 55.3 69.9 60.3 61.5 60.5 59.2 68.5 61.0 72.9 76.9 81.1 16.3 97.2 126.3 99.9 105.8 116.7 62.3 111.4 83.6 63.5 90.1 99.8 44.1 41.7 132.3 103.6 52.0 56.7 147.8 11.8 81.6 137.8 95.4 139.8 144.6 16.2 111.4 179.9 93.9 71.4 104.8 88.0 135.9 83.9 128.3 112.6 53.8 20.7 105.6 95.6 153.2 107.7 15.9 106.6 95.0 56.9 13.1 132.0 84.8 96.8 19.6 22.8 110.7 75.4 127.9 115.2 94.9 89.0 121.0 71.1 50.3 65.7 78.7 127.8 45.7 66.5 137.3 122.3 130.1 108.5 163.7 117.2 103.0 NR0B1 "AHC, AHCH, DAX1, DSS" ENSG00000169297 "Nuclear receptor subfamily 0 group B member 1" P51843 X 30304206-30309390 "Cancer-related genes, Disease related genes, Human disease related genes, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Receptor, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adrenal gland: 32.7;testis: 19.3" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 5.4;Ionocytes: 8.2;monocytes: 2.6;Oligodendrocyte precursor cells: 10.6;Theca cells: 4.9" "Cancer enhanced" "Detected in many" "lung cancer: 4.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "A549: 62.5;RT4: 19.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA061948, HPA067207" Supported "Nuclear speckles,Vesicles,Centriolar satellite" NA NA "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 68: Oligodendrocytes - Mixed function" "Nuclear speckles" "Vesicles, Centriolar satellite" "HPA061948: AB_2732673, HPA067207: AB_2732761" "unprognostic (1.50e-2)" "unprognostic (9.68e-2)" "unprognostic (9.47e-3)" "unprognostic (1.23e-1)" "unprognostic (2.81e-1)" "unprognostic (7.45e-3)" "unprognostic (4.83e-2)" "unprognostic (9.00e-2)" "unprognostic (1.33e-3)" 0.2 32.7 1.4 0.0 1.3 0.0 0.2 1.0 1.5 2.4 0.7 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.3 1.8 0.0 0.0 0.0 0.0 1.4 1.3 3.6 2.1 0.0 2.5 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 1.2 0.1 0.7 19.3 5.9 0.0 0.0 0.0 0.0 0.0 2.0 1.4 0.0 62.5 0.0 0.0 2.3 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 2.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 19.4 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 8.8 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.3 1.0 1.5 1.3 1.8 1.4 1.3 1.3 1.2 5.9 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.1 5.4 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.3 8.2 0.0 0.0 1.9 1.2 0.1 1.8 0.0 2.6 0.0 0.0 10.6 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.6 0.8 0.0 0.1 0.0 0.0 4.9 0.0 0.1 NR2F6 "EAR-2, EAR2, ERBAL2" ENSG00000160113 "Nuclear receptor subfamily 2 group F member 6" P10588 19 17231883-17245919 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 104.0" "Cell type enhanced" "Detected in all" "Distal enterocytes: 206.0;Hepatocytes: 148.4;Horizontal cells: 151.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BEWO: 187.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB079917 Supported "Nuclear speckles,Cytosol" NA Yes "Cluster 15: NK-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear speckles" Cytosol "CAB079917: AB_2635238" "unprognostic (1.48e-1)" "unprognostic (1.30e-1)" "unprognostic (2.17e-1)" "prognostic unfavorable (4.36e-4)" "unprognostic (1.08e-1)" "unprognostic (1.12e-1)" "unprognostic (3.07e-1)" "unprognostic (3.67e-1)" "unprognostic (7.20e-2)" "unprognostic (1.02e-2)" "unprognostic (2.39e-1)" "unprognostic (6.62e-2)" "unprognostic (9.68e-2)" "unprognostic (1.31e-1)" "unprognostic (2.29e-2)" "unprognostic (7.28e-3)" "unprognostic (1.37e-3)" 17.0 21.8 19.3 5.0 16.9 1.2 17.7 15.8 22.8 18.8 23.8 39.4 31.2 19.8 14.3 47.4 19.1 2.9 39.0 16.8 20.2 32.8 104.0 17.5 1.7 23.9 21.4 12.1 44.6 10.4 22.0 13.1 18.6 25.3 9.3 6.6 28.0 9.8 27.9 23.9 25.4 4.5 17.5 9.9 38.6 14.3 20.4 1.8 21.6 9.9 2.7 25.5 22.2 15.6 65.0 38.1 20.3 37.2 7.9 8.8 187.2 35.7 12.9 15.2 13.1 26.1 55.5 15.2 108.8 16.0 8.9 31.9 15.6 20.5 6.7 20.4 90.0 13.9 24.4 47.3 17.3 6.7 18.8 11.6 23.2 7.0 11.3 15.9 9.5 6.8 33.3 3.7 6.7 34.7 5.9 24.7 55.8 48.1 58.5 11.6 12.7 13.2 21.2 41.3 16.3 46.7 19.9 68.7 43.1 19.6 38.2 21.1 15.8 10.7 26.1 20.6 28.8 21.0 7.9 10.9 13.1 9.9 13.4 0.0 0.6 1.1 1.7 0.0 1.4 0.3 2.3 1.5 1.1 2.3 3.8 1.3 0.1 4.6 0.1 0.5 2.4 0.8 19.3 16.9 15.8 22.8 16.8 20.2 23.9 21.4 18.6 17.5 20.4 15.6 21.2 9.6 22.9 6.8 4.7 10.6 14.1 12.8 11.4 71.9 65.9 54.7 36.4 34.3 20.8 25.8 77.2 65.4 3.7 206.0 29.4 23.2 13.3 51.7 32.5 20.8 46.0 4.4 7.2 47.8 65.3 17.6 47.4 60.0 1.3 26.1 15.0 148.4 16.3 151.4 7.6 80.2 24.4 4.7 4.6 6.0 17.7 5.2 10.6 8.4 2.4 45.7 1.0 6.6 5.8 50.4 78.5 18.8 1.2 23.2 72.3 30.2 25.9 54.3 6.6 17.3 24.5 1.6 9.0 24.3 10.5 79.8 4.2 44.3 75.3 18.2 NR4A2 "HZF-3, NOT, NURR1, RNR1, TINUR" ENSG00000153234 "Nuclear receptor subfamily 4 group A member 2" P43354 2 156324437-156342348 "Cancer-related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 129.3;bone marrow: 130.8;ovary: 129.2" "Cell type enhanced" "Detected in many" "B-cells: 511.7;dendritic cells: 410.4;Langerhans cells: 782.3;Macrophages: 577.5;T-cells: 465.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 6.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HeLa: 16.0;HMC-1: 10.9;SK-MEL-30: 8.1;U-266/70: 14.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000543, CAB010481" Uncertain Supported "Nuclear speckles" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 20: HeLa - Mitochondria" "Cluster 41: Macrophages - Immune response" "Nuclear speckles" "CAB010481: AB_2298676, HPA000543: AB_1854631" "unprognostic (4.26e-2)" "unprognostic (2.14e-1)" "unprognostic (3.42e-2)" "unprognostic (4.10e-2)" "unprognostic (3.04e-2)" "unprognostic (5.26e-2)" "unprognostic (2.30e-1)" "unprognostic (6.14e-2)" "unprognostic (8.63e-2)" "unprognostic (3.88e-2)" "unprognostic (1.60e-2)" "unprognostic (2.89e-1)" "unprognostic (2.39e-2)" "unprognostic (3.58e-2)" "unprognostic (3.43e-1)" "unprognostic (9.29e-3)" "unprognostic (1.11e-1)" 40.0 129.3 4.3 24.5 44.1 130.8 15.6 36.2 8.8 18.3 5.9 9.5 2.9 15.0 1.7 11.4 28.2 32.7 36.6 15.1 3.6 19.2 20.2 18.8 6.3 3.2 9.2 129.2 9.2 8.8 54.0 5.2 2.8 25.6 18.7 5.3 19.2 15.5 11.6 12.8 7.8 14.5 0.9 4.6 19.9 5.6 2.5 9.7 15.2 7.8 1.4 50.9 14.0 6.4 0.9 1.3 0.5 1.8 3.2 0.7 0.9 1.1 5.5 0.4 1.3 0.0 3.3 0.0 1.2 0.4 0.4 1.6 2.6 0.7 0.4 1.3 1.4 1.0 16.0 0.0 0.6 0.7 10.9 0.6 1.2 0.4 0.4 2.1 0.3 0.0 1.6 1.0 1.1 1.9 0.0 0.8 2.1 1.5 0.8 0.2 0.7 3.3 0.6 0.8 2.7 0.1 2.6 4.1 8.1 0.3 0.2 1.0 0.7 2.9 0.8 0.7 0.4 14.2 1.8 0.0 5.3 1.0 7.0 1.9 1.7 2.4 1.0 0.3 0.5 0.4 0.3 0.5 1.9 0.3 0.5 0.2 6.5 0.0 0.7 0.0 0.4 0.5 4.3 44.1 36.2 8.8 15.1 3.6 3.2 9.2 2.8 0.9 2.5 6.4 70.7 25.6 124.7 7.8 511.7 218.6 25.8 87.5 298.7 11.8 120.8 160.1 11.9 17.2 58.3 71.7 50.1 4.7 410.4 35.0 0.0 13.1 36.7 209.6 33.9 111.9 206.4 12.0 5.8 9.1 6.5 164.9 103.9 349.7 349.3 4.3 45.0 6.8 125.1 0.0 0.8 95.4 42.7 161.1 782.3 37.2 4.1 577.5 241.9 5.6 7.9 1.6 3.1 4.0 2.3 11.7 41.9 0.7 203.5 49.1 25.9 0.4 54.6 33.4 13.1 63.0 169.8 1.8 3.3 230.2 213.7 9.9 465.1 34.4 57.5 29.5 NR5A2 "B1F2, FTF, FTZ-F1, FTZ-F1beta, hB1F, hB1F-2, LRH-1, LRH1" ENSG00000116833 "Nuclear receptor subfamily 5 group A member 2" O00482 1 200027614-200177420 "Nuclear receptors, Predicted intracellular proteins, Transcription factors, Transporters" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 17.8;liver: 38.6;pancreas: 61.1" "Cell type enriched" "Detected in many" 5 "Granulosa cells: 276.2" "Cancer enhanced" "Detected in many" "liver cancer: 6.6" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 4 "basophil: 3.2;neutrophil: 1.5" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.2" "Cell line enhanced" "Detected in some" "A549: 25.0;CACO-2: 6.2;HAP1: 14.9;HMC-1: 6.4;HUVEC TERT2: 20.4" "Region enhanced" "Detected in single" "hypothalamus: 1.2" "Not detected" "Not detected" "HPA005455, HPA017067" Approved Uncertain "Nuclear speckles" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 40: Granulosa cells - Unknown function" "Nuclear speckles" "HPA005455: AB_1078140, HPA017067: AB_1844767" "unprognostic (7.47e-2)" "unprognostic (1.43e-1)" "unprognostic (5.84e-2)" "unprognostic (1.56e-2)" "unprognostic (1.19e-2)" "unprognostic (6.63e-3)" "unprognostic (4.46e-2)" "unprognostic (3.78e-2)" "unprognostic (3.34e-1)" "unprognostic (8.50e-2)" "unprognostic (4.64e-2)" "unprognostic (1.44e-1)" "unprognostic (1.00e-7)" "unprognostic (5.48e-2)" "unprognostic (5.07e-2)" "unprognostic (9.23e-2)" "unprognostic (1.37e-1)" 5.4 0.4 0.5 2.6 0.2 0.9 3.7 0.5 0.3 3.4 0.2 11.9 17.4 3.3 1.4 0.9 2.2 8.0 1.0 0.3 2.8 0.7 38.6 2.7 2.1 0.7 0.6 1.0 61.1 0.4 0.1 0.4 0.8 1.6 13.1 0.2 0.5 0.8 1.1 1.1 17.8 4.3 0.4 0.2 1.3 0.8 0.8 0.5 0.9 0.7 1.4 1.8 1.2 0.7 0.0 25.0 0.0 0.1 0.0 0.2 0.6 0.0 0.4 0.0 0.0 6.2 0.1 0.0 0.0 0.0 0.7 0.7 14.9 0.0 0.0 3.3 1.1 0.0 0.3 2.7 0.5 0.1 6.4 0.1 0.0 0.0 0.1 0.0 20.4 0.1 0.0 0.3 0.0 0.6 0.0 0.4 0.9 0.0 0.3 0.4 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.1 1.7 4.7 0.3 0.1 1.0 0.2 0.1 0.2 3.4 2.3 2.6 0.3 0.2 0.1 3.2 0.4 0.4 0.2 0.2 0.2 0.3 0.3 0.3 0.1 0.4 0.4 0.3 1.5 0.5 0.2 0.5 0.4 0.1 0.5 0.2 0.5 0.3 0.3 2.8 0.7 0.6 0.8 0.4 0.8 0.7 23.7 0.0 1.7 0.3 0.2 1.9 0.1 0.0 0.0 0.2 0.2 0.0 9.9 32.9 0.0 0.0 0.0 0.0 0.3 37.5 0.0 38.2 0.4 0.3 0.3 32.4 4.9 2.7 0.4 54.5 0.0 0.8 0.0 0.2 13.3 276.2 38.6 38.5 0.1 0.0 0.6 13.8 0.0 4.9 1.5 0.3 0.6 0.6 0.0 0.0 3.1 0.0 0.0 1.0 0.3 22.0 21.8 0.0 1.2 0.3 49.9 0.0 0.8 0.3 0.0 0.5 6.1 0.1 0.1 0.0 1.4 0.0 0.3 0.1 32.3 0.2 NSL1 "C1orf48, DC8, DKFZP566O1646, MIS14" ENSG00000117697 "NSL1 component of MIS12 kinetochore complex" Q96IY1 1 212726153-212791782 "Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA045761, HPA053721" Enhanced Supported "Nuclear speckles" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "HPA045761: AB_2679444, HPA053721: AB_2682240" "unprognostic (1.47e-1)" "unprognostic (1.67e-1)" "unprognostic (8.08e-2)" "unprognostic (2.67e-2)" "unprognostic (2.58e-2)" "unprognostic (1.78e-2)" "unprognostic (8.22e-3)" "unprognostic (3.55e-1)" "unprognostic (4.78e-2)" "unprognostic (6.09e-3)" "unprognostic (3.44e-3)" "unprognostic (1.58e-1)" "unprognostic (3.10e-3)" "unprognostic (2.59e-1)" "unprognostic (1.04e-2)" "unprognostic (1.67e-1)" "unprognostic (6.66e-2)" 16.7 14.5 13.8 19.4 16.9 19.1 11.2 17.1 17.5 12.8 15.0 13.3 17.5 14.5 8.0 15.3 13.9 15.0 24.9 13.4 14.9 16.0 19.3 12.5 27.0 18.0 14.9 16.8 12.5 13.9 11.0 17.6 17.5 12.8 10.1 12.6 13.9 10.0 22.5 8.8 17.5 13.1 17.3 19.4 11.7 13.5 14.8 22.7 15.0 15.6 16.7 13.6 10.1 21.3 39.7 44.3 45.0 43.3 18.9 19.5 59.4 32.5 22.1 38.7 33.2 37.3 42.2 55.6 29.4 18.7 21.6 28.4 35.6 29.9 20.1 102.9 33.6 37.0 31.2 61.8 21.7 62.5 34.9 20.2 14.6 39.6 19.8 17.8 28.8 62.9 83.0 45.7 24.6 23.1 80.6 24.6 82.9 20.6 32.8 69.2 68.1 61.5 31.3 19.8 41.1 57.0 46.0 22.3 55.7 33.3 65.6 44.9 33.3 39.4 34.1 36.4 54.5 26.4 76.3 73.8 33.7 42.2 50.7 21.8 49.3 63.1 35.9 62.3 43.0 59.0 38.8 39.2 55.6 47.4 46.7 41.9 49.6 45.3 64.3 53.8 51.2 60.7 13.8 16.9 17.1 17.5 13.4 14.9 18.0 14.9 17.5 17.3 14.8 21.3 39.4 16.0 20.7 25.5 43.5 14.8 21.2 51.4 31.3 34.1 22.8 26.8 22.4 31.5 28.1 18.4 14.6 64.0 40.9 14.7 43.0 32.2 29.2 19.9 29.0 32.0 21.7 50.7 50.2 21.1 62.2 28.9 13.3 15.1 15.2 31.6 29.6 27.9 61.6 33.7 50.1 14.1 30.5 68.2 28.5 15.2 34.8 44.6 19.6 33.7 56.0 37.1 35.0 36.2 68.9 22.7 15.9 32.7 26.7 10.5 32.5 58.5 25.6 32.7 59.2 30.2 32.6 48.7 65.5 22.7 16.2 20.9 36.6 27.0 18.5 10.3 NUP43 "bA350J20.1, FLJ13287" ENSG00000120253 "Nucleoporin 43" Q8NFH3 6 149724315-149749665 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Chromosome partition, Mitosis, mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 78.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027126, HPA027291, HPA028500" Enhanced Approved "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 16: Immune cells - Immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nuclear speckles" Cytosol "HPA027126: AB_10599301, HPA027291: AB_10601851, HPA028500: AB_10602287" "prognostic unfavorable (2.08e-4)" "unprognostic (3.02e-1)" "unprognostic (3.86e-2)" "unprognostic (1.45e-3)" "unprognostic (2.29e-1)" "unprognostic (8.19e-3)" "prognostic unfavorable (7.13e-7)" "unprognostic (5.14e-2)" "unprognostic (2.45e-1)" "unprognostic (2.35e-1)" "unprognostic (1.11e-1)" "unprognostic (1.06e-2)" "unprognostic (2.74e-2)" "unprognostic (6.25e-3)" "unprognostic (2.02e-1)" "unprognostic (2.72e-2)" "unprognostic (3.60e-2)" 8.4 8.6 6.2 11.4 7.5 6.2 13.6 7.2 6.9 9.7 6.5 9.4 8.7 9.8 7.5 9.5 8.2 6.4 10.8 5.6 6.6 9.9 9.6 8.0 15.9 6.6 6.6 9.1 12.2 8.9 5.6 11.4 6.9 10.3 9.7 9.8 8.8 9.2 14.2 13.5 10.9 9.4 6.6 13.6 9.8 7.9 6.5 12.8 11.1 11.6 17.0 9.0 9.1 8.3 21.1 34.9 31.1 49.6 20.0 23.7 48.9 36.3 20.3 34.0 43.0 49.5 19.5 61.4 36.6 20.2 32.1 33.5 54.6 31.6 58.3 27.8 38.2 70.9 35.5 49.6 13.4 73.2 44.1 15.3 16.4 49.9 33.1 13.0 27.5 34.6 71.4 33.6 29.6 20.7 52.2 30.4 28.3 24.1 21.0 50.2 43.2 20.6 23.2 28.9 12.9 21.2 43.4 27.1 14.2 25.6 28.7 30.9 21.3 28.3 30.2 41.2 53.9 20.5 43.3 63.9 25.2 49.3 40.5 2.9 4.9 3.4 3.5 5.4 3.8 4.3 4.2 3.5 2.6 6.2 4.3 5.5 1.9 3.7 4.8 5.0 4.9 2.2 6.2 7.5 7.2 6.9 5.6 6.6 6.6 6.6 6.9 6.6 6.5 8.3 5.8 3.2 7.8 9.1 11.5 7.9 5.5 4.7 2.8 11.9 4.5 5.0 14.3 11.5 5.2 3.7 6.2 10.9 11.3 4.7 3.9 9.0 33.3 4.3 8.7 5.7 10.2 7.6 4.8 7.8 12.2 6.4 6.1 6.0 0.0 12.8 8.2 4.4 7.8 6.7 5.1 6.9 2.0 11.9 6.9 78.9 10.2 6.5 8.8 9.4 15.1 10.5 9.2 11.1 17.4 6.6 2.3 10.5 8.7 6.2 3.9 5.4 4.2 9.5 13.1 6.9 22.1 7.1 9.2 5.5 8.5 6.6 7.6 7.4 8.4 6.7 OIP5 "CT86, hMIS18beta, MIS18B" ENSG00000104147 "Opa interacting protein 5" O43482 15 41309273-41332591 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.3;skeletal muscle: 10.3;testis: 20.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 45.9;Extravillous trophoblasts: 24.0;Spermatocytes: 110.6;Spermatogonia: 56.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA052271, HPA059602" Enhanced Supported "Nuclear speckles,Vesicles" NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear speckles" Vesicles "HPA052271: AB_2681780, HPA059602: AB_2684079" "unprognostic (5.17e-2)" "unprognostic (7.26e-2)" "unprognostic (3.07e-1)" "unprognostic (1.59e-2)" "unprognostic (6.94e-2)" "unprognostic (6.58e-2)" "prognostic unfavorable (1.79e-4)" "prognostic unfavorable (2.26e-4)" "unprognostic (2.71e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (9.34e-5)" "unprognostic (5.51e-2)" "unprognostic (0.00e+0)" "unprognostic (3.84e-2)" "unprognostic (2.02e-1)" "unprognostic (5.75e-2)" "unprognostic (2.86e-2)" 0.6 1.7 0.1 3.3 0.2 10.3 1.2 1.2 0.4 0.9 0.2 4.1 3.5 0.8 0.3 3.8 0.4 0.6 1.5 0.2 0.2 0.3 1.2 0.5 5.8 0.2 0.4 1.5 0.3 0.1 0.1 2.3 0.4 0.5 3.9 0.7 0.8 0.6 10.3 3.3 3.9 1.1 0.1 1.7 1.5 20.9 0.2 9.1 0.4 0.8 5.2 0.7 1.3 0.5 33.7 17.8 34.3 24.9 1.7 2.1 32.4 20.0 9.3 24.5 26.1 31.8 16.2 19.8 17.0 7.7 37.8 51.0 35.7 16.1 19.2 42.4 40.1 42.4 49.8 33.6 0.4 46.5 22.1 0.7 3.2 13.8 14.5 5.2 21.1 40.8 59.4 37.3 16.5 16.3 27.1 34.8 30.9 50.4 37.9 32.9 28.4 30.5 11.1 15.4 53.7 17.5 33.7 34.3 9.6 13.7 33.7 26.3 10.0 24.5 37.3 24.6 36.6 17.0 83.2 71.1 7.1 56.5 35.9 0.0 0.4 0.5 0.2 0.7 0.8 1.0 0.7 0.8 0.7 1.2 1.3 0.8 0.0 1.2 0.4 4.1 3.1 0.8 0.1 0.2 1.2 0.4 0.2 0.2 0.2 0.4 0.4 0.1 0.2 0.5 0.2 0.0 0.5 1.0 2.7 4.1 0.9 3.6 1.2 0.0 1.1 2.2 0.2 0.0 1.8 0.0 0.0 15.0 1.7 2.3 0.0 0.4 12.0 1.9 0.6 0.9 0.0 45.9 2.2 0.4 24.0 1.7 5.1 1.1 1.3 5.2 0.0 0.8 7.5 0.0 2.1 3.0 8.2 2.2 1.8 10.8 0.9 1.2 0.0 0.0 0.6 1.1 2.1 1.5 2.5 0.2 0.5 1.2 10.9 0.4 0.9 0.3 0.0 0.3 6.6 1.0 1.1 110.6 56.8 8.3 2.4 3.8 1.2 2.1 7.6 0.9 OSER1 "C20orf111, dJ1183I21.1, HSPC207, Osr1, Perit1" ENSG00000132823 "Oxidative stress responsive serine rich 1" Q9NX31 20 44195939-44210771 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 842.5;Late spermatids: 2257.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045125 Approved Approved "Nucleoli,Nucleoli rim,Nuclear speckles" NA Yes "Cluster 5: Granulocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoli, Nucleoli rim, Nuclear speckles" "HPA045125: AB_10961629" "unprognostic (2.77e-2)" "unprognostic (3.01e-2)" "unprognostic (3.22e-1)" "prognostic unfavorable (2.58e-5)" "unprognostic (1.18e-1)" "unprognostic (6.07e-2)" "unprognostic (8.44e-3)" "unprognostic (3.31e-1)" "unprognostic (1.14e-1)" "unprognostic (8.78e-2)" "unprognostic (8.01e-3)" "unprognostic (9.87e-2)" "unprognostic (3.96e-1)" "unprognostic (2.14e-1)" "unprognostic (2.45e-1)" "unprognostic (8.39e-2)" "unprognostic (1.06e-1)" 43.4 26.6 22.0 22.3 23.2 128.5 42.3 24.7 26.8 37.2 21.9 39.2 27.2 35.1 30.7 46.2 34.9 23.6 37.5 21.9 24.1 35.7 38.1 36.0 27.7 25.0 23.7 42.5 23.5 29.4 24.3 25.2 24.4 36.7 24.7 25.1 36.9 21.5 110.1 51.8 37.3 25.7 24.1 40.1 32.9 116.3 23.8 25.3 37.7 61.1 32.5 44.6 39.2 27.8 50.6 37.1 28.9 22.6 75.2 54.6 32.7 45.0 69.6 71.0 64.1 93.9 54.7 49.1 44.3 43.3 96.1 73.9 31.8 42.7 59.3 16.2 20.1 16.1 99.8 66.8 41.6 27.6 26.8 64.5 72.3 47.1 86.1 38.7 32.8 30.6 24.9 64.9 40.2 75.8 22.5 35.9 25.7 46.5 39.3 32.8 46.4 35.0 37.3 34.7 28.2 27.5 64.2 90.5 62.2 33.9 45.1 25.6 27.8 60.6 45.3 35.8 39.7 44.3 49.1 48.4 42.6 20.6 31.1 264.8 68.4 119.5 50.0 68.3 54.1 120.1 57.1 49.7 60.7 115.2 67.7 61.8 306.7 67.7 100.2 39.7 73.8 91.5 22.0 23.2 24.7 26.8 21.9 24.1 25.0 23.7 24.4 24.1 23.8 27.8 51.2 19.2 21.0 14.4 70.0 259.4 137.6 95.4 101.3 10.3 69.1 75.2 38.7 18.6 61.3 12.9 4.2 40.4 48.6 58.6 37.2 45.1 842.5 94.7 48.0 36.8 49.5 25.0 9.0 36.4 38.2 48.6 37.2 175.1 33.0 22.9 18.5 27.9 43.4 11.8 9.0 34.6 65.1 30.6 111.1 2257.1 40.7 55.2 76.5 5.6 84.2 31.0 30.9 5.0 12.5 49.3 87.7 35.3 40.6 91.4 68.1 33.5 36.9 14.8 19.7 47.0 45.6 194.8 71.7 50.4 198.5 173.6 55.2 22.3 47.5 119.4 PABPN1 "OPMD, PAB2, PABP2" ENSG00000100836 "Poly(A) binding protein nuclear 1" Q86U42 14 23321289-23326185 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing" RNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" HPA000637 Supported Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 43: Testis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "Nuclear speckles" "HPA000637: AB_1079553" "unprognostic (5.11e-3)" "unprognostic (2.65e-2)" "unprognostic (7.20e-2)" "unprognostic (2.95e-2)" "unprognostic (1.05e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (3.55e-4)" "unprognostic (1.88e-2)" "unprognostic (1.47e-1)" "unprognostic (1.95e-3)" "prognostic favorable (9.66e-4)" "unprognostic (5.88e-2)" "prognostic unfavorable (2.41e-7)" "unprognostic (1.52e-2)" "unprognostic (1.31e-2)" "unprognostic (1.07e-1)" "unprognostic (8.25e-3)" 133.2 178.7 187.0 86.4 183.9 136.9 127.7 193.4 249.3 165.6 184.5 184.1 107.6 176.0 130.3 151.0 175.6 63.4 138.1 185.8 196.6 187.7 194.8 130.0 103.9 186.0 182.2 176.3 138.8 101.0 199.0 79.7 181.6 179.4 101.5 126.6 130.4 85.8 131.5 136.9 167.8 97.4 175.6 174.3 159.3 230.1 186.3 147.6 189.8 94.1 116.5 146.3 144.0 190.4 127.2 133.9 298.3 216.6 125.5 143.1 191.4 120.4 121.6 168.4 157.4 168.0 223.0 229.7 67.0 157.0 180.6 186.4 337.7 169.7 230.7 195.2 116.7 173.5 208.1 435.5 145.2 273.5 220.2 157.1 164.7 125.0 149.1 240.9 188.1 196.0 164.5 174.6 159.8 239.6 296.1 334.5 328.6 151.2 149.3 289.1 114.8 136.2 196.1 256.2 205.6 159.9 161.4 143.2 129.6 196.9 114.2 196.3 153.2 112.1 153.8 110.4 161.8 207.3 153.0 276.5 51.4 221.4 138.7 15.7 7.6 8.5 6.0 5.8 4.9 7.4 6.1 5.5 6.1 9.3 7.5 7.0 10.0 10.1 7.2 13.8 7.6 2.5 187.0 183.9 193.4 249.3 185.8 196.6 186.0 182.2 181.6 175.6 186.3 190.4 66.3 35.3 49.4 0.0 83.3 157.8 84.4 74.0 158.2 120.1 110.2 89.5 14.3 77.2 51.2 126.9 146.0 70.0 102.5 85.5 13.7 52.6 55.6 71.8 80.8 75.0 161.4 94.2 0.0 57.2 67.4 72.4 68.8 78.6 24.1 169.3 66.0 121.6 63.2 77.4 0.0 107.2 54.9 84.7 119.0 45.9 81.1 85.5 53.4 0.0 104.4 55.8 65.9 0.0 0.0 59.2 91.6 59.8 102.2 88.7 88.9 40.3 49.8 80.2 72.3 57.5 85.0 41.8 33.3 187.4 179.9 62.8 67.3 107.6 108.1 114.6 PACSIN2 SDPII ENSG00000100266 "Protein kinase C and casein kinase substrate in neurons 2" Q9UNF0 22 42835412-43015149 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 95.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049854, HPA056520" Enhanced Supported "Nuclear speckles,Vesicles,Plasma membrane,Cytosol" NA NA 2400000 "Cluster 52: Eosinophils - Transcription" "Cluster 25: Pancreas - Digestion" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear speckles, Vesicles, Cytosol" "Plasma membrane" "HPA049854: AB_2680915, HPA056520: AB_2683163" "unprognostic (5.62e-3)" "unprognostic (1.22e-1)" "unprognostic (1.71e-2)" "unprognostic (1.64e-3)" "unprognostic (1.63e-2)" "unprognostic (3.96e-1)" "prognostic unfavorable (7.33e-4)" "unprognostic (4.48e-2)" "unprognostic (3.40e-2)" "unprognostic (2.82e-3)" "unprognostic (3.09e-2)" "unprognostic (1.00e-1)" "prognostic favorable (1.09e-13)" "unprognostic (2.87e-1)" "unprognostic (1.11e-1)" "unprognostic (6.20e-2)" "unprognostic (2.95e-1)" 40.8 74.3 25.7 37.1 29.1 29.3 40.7 34.2 27.3 37.5 32.3 61.7 40.8 39.1 21.2 34.1 35.3 45.3 55.7 27.7 39.2 47.1 41.1 50.9 34.2 40.5 36.8 31.4 162.4 29.4 39.9 34.2 40.8 47.0 41.6 28.2 43.5 27.4 49.8 39.5 38.1 30.4 30.7 35.9 51.5 19.5 32.5 28.7 43.9 42.4 26.4 36.5 34.5 31.1 76.3 78.3 64.6 41.5 32.6 34.6 52.9 67.8 40.7 59.9 49.7 82.1 43.8 35.2 56.1 50.6 40.8 52.8 42.5 72.1 39.3 36.1 42.4 56.8 39.4 117.8 46.1 40.5 118.1 33.4 69.8 79.1 34.3 48.7 49.9 32.1 49.9 24.9 52.2 49.7 43.1 63.3 35.6 110.4 32.7 52.3 96.5 23.8 68.9 44.4 41.9 18.7 81.1 55.2 155.8 41.5 40.1 53.1 74.3 44.5 56.4 50.0 40.5 18.4 27.2 38.4 42.7 35.4 99.1 26.1 18.5 47.4 6.8 32.2 7.3 11.3 7.8 5.8 21.5 11.6 7.6 5.8 95.7 16.8 33.9 7.9 12.1 14.1 25.7 29.1 34.2 27.3 27.7 39.2 40.5 36.8 40.8 30.7 32.5 31.1 31.7 70.5 60.6 20.2 20.6 23.2 43.4 23.9 21.1 15.7 37.4 31.1 26.3 24.3 37.2 46.0 39.6 34.4 19.9 142.6 45.0 80.2 3.6 51.6 31.3 28.6 24.7 12.6 22.7 65.4 29.6 20.9 36.7 57.4 71.0 14.7 16.1 22.3 42.7 6.7 41.0 49.5 30.5 38.5 50.0 6.2 21.8 44.9 83.6 54.4 51.3 8.4 7.2 29.1 19.5 70.9 62.3 23.3 13.1 50.6 32.0 55.0 30.7 24.9 92.1 23.5 82.9 22.6 27.6 22.5 16.9 48.2 19.1 13.8 42.2 30.3 PAGE3 "CT16.6, GAGED1, PAGE-3" ENSG00000204279 "PAGE family member 3" Q5JUK9 X 55258412-55264846 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 49 "testis: 7.6" "Group enriched" "Detected in some" 63 "Early spermatids: 107.9;Late spermatids: 312.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045032, HPA062248" Uncertain Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" "Nuclear speckles" Nucleoplasm "HPA045032: , HPA062248: AB_2684725" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 107.9 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 312.1 0.9 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.6 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PARN DAN ENSG00000140694 "Poly(A)-specific ribonuclease" O95453 16 14435700-14632728 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Nonsense-mediated mRNA decay" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Disease variant, Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006314, CAB011673, HPA012010" Supported Supported "Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "CAB011673: AB_778216, HPA006314: AB_1079567, HPA012010: AB_1854976" "unprognostic (2.54e-1)" "unprognostic (3.43e-2)" "unprognostic (1.55e-1)" "unprognostic (2.23e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (4.64e-4)" "unprognostic (2.99e-3)" "unprognostic (5.07e-2)" "unprognostic (1.32e-1)" "unprognostic (1.94e-1)" "unprognostic (2.16e-3)" "unprognostic (1.75e-1)" "unprognostic (1.52e-1)" "unprognostic (3.25e-2)" "unprognostic (2.46e-1)" "unprognostic (3.10e-3)" "unprognostic (1.09e-2)" 16.6 20.2 10.8 13.9 12.1 9.2 15.9 11.7 11.4 17.2 12.0 19.3 11.8 19.1 24.7 15.6 16.0 13.4 14.8 10.6 14.0 12.7 16.4 14.2 21.2 11.7 11.9 16.4 16.5 21.1 16.3 15.6 11.9 16.1 16.8 7.0 15.3 17.1 16.8 17.9 16.1 18.0 11.3 15.7 16.2 18.1 12.6 21.6 20.6 9.7 23.4 19.3 16.0 13.5 28.0 39.9 17.6 22.9 32.9 33.2 20.3 24.4 32.4 29.8 28.3 21.9 28.7 56.2 63.1 32.3 25.3 30.4 46.7 32.3 41.0 42.9 29.4 28.8 24.2 53.2 35.5 46.0 36.2 32.5 38.5 32.0 43.1 25.5 22.5 32.6 28.5 29.9 32.5 44.9 36.7 33.1 26.0 28.2 16.7 56.2 36.1 57.1 23.1 17.1 18.7 16.9 53.4 29.6 36.3 28.6 31.6 28.0 21.2 31.5 15.8 16.4 26.9 32.5 31.0 63.5 34.6 30.8 35.8 8.9 8.0 15.8 8.6 13.2 7.7 16.0 10.4 12.4 13.6 9.4 14.2 14.4 6.2 15.0 15.6 8.3 19.1 7.1 10.8 12.1 11.7 11.4 10.6 14.0 11.7 11.9 11.9 11.3 12.6 13.5 18.0 32.1 39.1 37.9 26.2 7.1 7.8 9.7 21.6 13.0 13.4 14.0 22.3 7.2 11.8 11.0 8.4 29.2 24.7 13.6 11.7 14.2 14.1 15.2 20.5 15.2 14.9 20.4 48.0 12.9 23.2 19.5 21.9 21.7 2.5 19.2 11.7 15.6 14.8 8.4 48.2 14.3 6.1 14.2 5.8 6.3 21.1 18.2 10.6 54.4 35.8 10.3 52.5 38.2 72.4 15.2 10.6 17.7 23.0 7.1 12.2 10.8 19.2 10.8 19.7 13.1 15.0 70.5 70.5 20.0 8.2 22.4 21.5 20.1 13.4 4.8 PASD1 CT63 ENSG00000166049 "PAS domain containing repressor 1" Q8IV76 X 151563675-151676739 "Predicted intracellular proteins" "Biological rhythms" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 161 "testis: 16.1" "Group enriched" "Detected in some" 5 "Spermatocytes: 19.3;Spermatogonia: 57.5" "Cancer enhanced" "Detected in some" "melanoma: 0.7;testis cancer: 0.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "BEWO: 34.8;HMC-1: 55.3;U-266/84: 27.8" "Not detected" "Not detected" "HPA011122, HPA011152" Enhanced Enhanced "Nuclear speckles" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 3: HMC-1 - Innate immune response" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nuclear speckles" "HPA011122: AB_1854990, HPA011152: AB_1854991" "unprognostic (3.34e-1)" "unprognostic (1.02e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 55.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.3 27.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 6.6 0.0 0.0 19.3 57.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PCBP1 "hnRNP-E1, hnRNP-X, HNRPE1, HNRPX" ENSG00000169564 "Poly(rC) binding protein 1" Q15365 2 70087477-70089203 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Viral RNA replication" "DNA-binding, Ribonucleoprotein, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037113, HPA043803, HPA068497" Approved Enhanced "Nuclear speckles,Cytoplasmic bodies" No No 1600000 "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "Cytoplasmic bodies" "CAB037113: AB_1840915, HPA043803: AB_2678676, HPA068497: AB_2685996" "unprognostic (1.63e-1)" "unprognostic (2.69e-2)" "unprognostic (1.01e-1)" "unprognostic (7.08e-2)" "unprognostic (5.37e-1)" "unprognostic (1.63e-2)" "unprognostic (8.33e-2)" "unprognostic (9.94e-3)" "unprognostic (2.01e-1)" "unprognostic (2.70e-1)" "unprognostic (6.65e-2)" "unprognostic (2.77e-1)" "prognostic favorable (1.71e-5)" "unprognostic (3.85e-2)" "unprognostic (9.25e-2)" "unprognostic (1.22e-1)" "unprognostic (5.90e-2)" 278.3 276.3 145.5 199.8 155.0 390.0 240.4 168.5 203.5 209.3 159.1 259.9 172.8 253.9 142.6 278.4 193.8 134.9 223.2 142.1 155.6 218.1 304.3 233.6 227.1 163.7 146.9 186.0 249.9 174.6 140.2 194.8 159.2 143.9 125.8 90.5 185.0 139.5 782.3 216.6 203.1 172.4 163.8 241.3 214.5 95.2 150.4 301.0 170.8 308.3 209.6 233.8 206.0 190.9 384.9 387.5 327.1 257.5 345.1 262.4 525.9 280.5 257.2 272.0 227.0 453.0 250.6 522.9 140.9 320.7 293.7 334.7 388.4 408.6 276.5 376.2 299.9 419.2 219.5 701.3 388.0 350.8 385.8 230.3 261.6 224.5 310.5 203.4 350.7 138.9 437.2 375.6 346.2 475.7 454.7 524.7 331.5 361.1 253.2 362.9 358.0 527.1 375.5 389.6 309.7 249.1 230.3 465.8 342.1 229.8 277.6 314.2 325.1 253.5 317.6 217.6 359.4 495.7 551.2 531.7 268.6 480.4 319.5 42.6 89.7 141.5 80.3 92.5 73.8 41.1 62.1 69.3 82.9 36.4 62.8 71.2 138.2 95.4 80.5 58.9 81.7 100.5 145.5 155.0 168.5 203.5 142.1 155.6 163.7 146.9 159.2 163.8 150.4 190.9 241.0 153.8 132.7 27.4 312.7 484.0 296.0 192.1 196.9 64.9 270.8 212.6 0.6 208.8 134.5 196.8 22.9 372.4 208.7 401.7 272.0 196.0 34.4 187.6 220.8 242.8 178.6 485.3 19.1 199.2 470.1 196.9 227.9 284.8 114.2 129.6 227.0 392.7 385.7 58.9 18.0 239.8 138.4 509.2 795.9 34.4 186.1 382.4 300.6 30.0 422.9 122.3 347.1 14.1 49.1 211.7 311.7 186.5 357.1 278.5 338.4 481.0 128.6 56.1 170.9 222.9 241.9 131.0 65.5 267.0 545.8 703.4 291.2 148.4 232.9 366.6 PCDHA5 "CNR6, CNRN6, CNRS6, CRNR6, PCDH-ALPHA5" ENSG00000204965 "Protocadherin alpha 5" Q9Y5H7 5 140821604-141012347 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "brain: 3.3" "Cell type enriched" "Detected in some" 4 "Horizontal cells: 6.7" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 3.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 1.3;EFO-21: 3.4;T-47d: 3.7;WM-115: 1.3" "Low region specificity" "Detected in many" HPA044557 Approved Approved "Nuclear speckles,Plasma membrane,Mitochondria" NA NA "Cluster 6: Brain - Smell perception" "Cluster 6: T47d - Mammary gland" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "Nuclear speckles, Mitochondria" "HPA044557: AB_10970597" "unprognostic (4.95e-2)" "unprognostic (6.23e-2)" "unprognostic (2.06e-1)" "unprognostic (8.81e-4)" "unprognostic (5.10e-2)" "unprognostic (6.25e-3)" "unprognostic (6.74e-2)" "unprognostic (9.79e-2)" "unprognostic (2.46e-2)" "unprognostic (4.49e-2)" "unprognostic (1.44e-2)" "unprognostic (1.10e-4)" "unprognostic (9.30e-4)" "unprognostic (1.07e-1)" "unprognostic (1.39e-1)" "unprognostic (8.17e-5)" "unprognostic (2.11e-1)" 0.1 0.1 0.6 0.0 1.0 0.0 0.1 3.3 1.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.2 0.0 0.5 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.3 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 3.7 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 1.0 3.3 1.1 0.9 0.0 0.1 0.1 0.2 0.0 0.1 0.6 0.3 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PCLO "ACZ, DKFZp779G1236, KIAA0559" ENSG00000186472 "Piccolo presynaptic cytomatrix protein" Q9Y6V0 7 82754012-83162930 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Neurodegeneration "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 25.6;pituitary gland: 11.1;retina: 21.7" "Group enriched" "Detected in many" 5 "Excitatory neurons: 655.4;Inhibitory neurons: 746.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 25.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 28 "REH: 263.3;U-2 OS: 284.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015858, HPA029579, CAB079012" Approved Supported Approved "Nuclear speckles,Plasma membrane" NA NA 6000000 "Cluster 58: Brain - Synaptic function" "Cluster 14: REH - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear speckles, Plasma membrane" "CAB079012: , HPA015858: AB_1855071, HPA029579: AB_10602044" "unprognostic (1.32e-2)" "unprognostic (1.99e-1)" "unprognostic (9.33e-2)" "unprognostic (1.31e-1)" "unprognostic (2.08e-2)" "unprognostic (1.52e-1)" "unprognostic (4.49e-3)" "unprognostic (6.14e-2)" "unprognostic (4.61e-2)" "unprognostic (1.82e-1)" "unprognostic (3.00e-1)" "unprognostic (1.56e-1)" "unprognostic (4.79e-6)" "unprognostic (5.15e-2)" "unprognostic (2.42e-2)" "unprognostic (1.36e-5)" "unprognostic (6.62e-5)" 1.8 4.2 4.0 0.2 5.5 0.0 2.4 25.6 22.4 1.5 0.0 2.1 1.5 0.3 3.8 2.3 1.0 0.9 1.4 7.8 1.7 4.4 0.1 0.8 0.1 0.0 0.0 0.8 3.9 4.4 11.1 0.3 0.0 2.5 1.7 21.7 2.5 2.5 0.1 2.0 1.7 0.1 0.0 0.5 1.5 3.7 1.3 1.2 4.6 0.1 0.2 0.6 2.6 4.2 1.2 1.6 1.9 0.0 0.8 0.1 0.0 0.7 0.7 0.5 1.0 0.3 0.7 0.0 0.0 0.8 7.7 0.6 5.7 2.4 2.4 0.3 0.8 0.0 1.2 0.1 0.0 0.8 0.2 0.4 1.8 0.0 9.6 0.5 0.0 0.1 0.0 0.0 0.8 0.8 0.2 0.0 2.0 1.0 4.7 263.3 4.2 0.0 1.9 0.9 4.9 3.4 0.2 2.7 0.6 1.2 3.4 0.6 0.0 0.0 284.5 1.2 0.6 0.2 0.0 0.5 1.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 5.5 25.6 22.4 7.8 1.7 0.0 0.0 0.0 0.0 1.3 4.2 0.6 9.6 17.9 40.5 0.0 2.5 9.0 3.2 13.6 121.9 11.0 9.7 31.2 22.8 12.6 1.8 131.3 1.9 0.0 22.9 7.9 6.4 13.0 7.4 6.7 2.5 60.1 0.0 655.4 4.9 0.4 2.4 20.4 13.5 0.0 24.2 0.0 0.2 1.7 85.8 746.4 15.0 2.0 0.0 0.0 7.9 2.8 0.4 0.0 50.6 0.0 16.2 0.0 73.9 73.7 2.5 21.9 6.4 0.0 3.9 13.5 23.0 7.7 86.9 0.0 0.3 3.2 5.0 19.5 19.3 3.4 0.7 0.3 37.5 9.3 6.0 PCP2 "GPSM4, MGC41903" ENSG00000174788 "Purkinje cell protein 2" Q8IVA1 19 7631611-7633719 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 53.4;retina: 33.3;testis: 112.4" "Cell type enriched" "Detected in many" 4 "Late spermatids: 4139.3" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 6 "cerebellum: 53.4;white matter: 16.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 8.4;Karpas-707: 4.2;NB-4: 17.7" "Region enriched" "Detected in many" 44 "cerebellum: 2160.4" "Region enriched" "Detected in all" 28 "cerebellum: 552.9" HPA057428 Approved "Nuclear speckles,Vesicles" Yes NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 21: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear speckles" Vesicles "HPA057428: AB_2683436" "prognostic favorable (7.93e-4)" "unprognostic (6.06e-2)" "unprognostic (1.19e-2)" "unprognostic (4.43e-2)" "unprognostic (1.49e-1)" "unprognostic (1.79e-4)" "unprognostic (1.19e-1)" "unprognostic (4.88e-5)" "unprognostic (1.11e-1)" "unprognostic (6.23e-2)" "unprognostic (9.15e-3)" "unprognostic (6.01e-2)" "unprognostic (1.36e-2)" "unprognostic (8.17e-2)" "unprognostic (1.18e-1)" "unprognostic (8.70e-2)" "prognostic favorable (2.76e-5)" 0.4 1.6 0.4 1.1 0.6 3.7 5.5 53.4 2.3 2.1 0.0 0.6 1.4 0.9 3.3 2.0 2.4 2.3 2.2 0.5 0.0 8.0 3.7 2.2 3.0 0.1 3.5 0.1 5.4 1.1 1.4 0.4 5.5 5.9 0.3 33.3 16.3 1.9 0.2 7.0 1.6 0.0 0.1 3.0 3.1 112.4 0.0 3.1 5.7 0.0 1.4 0.9 1.6 16.8 1.8 0.4 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.7 1.6 0.7 1.1 0.0 0.0 1.3 0.0 0.2 0.0 0.8 0.6 2.6 2.8 0.1 0.0 0.3 8.4 0.0 0.6 0.0 0.0 0.0 0.0 0.7 0.2 4.2 0.0 0.3 0.3 17.7 0.4 0.3 0.0 0.8 0.2 0.7 0.8 0.1 0.1 0.0 1.4 1.4 0.0 0.4 3.7 3.4 0.2 0.0 0.5 0.4 0.0 1.4 0.7 0.2 0.0 2.0 0.0 0.0 0.1 0.0 0.3 0.0 0.4 0.1 0.1 0.1 0.2 0.3 0.2 0.3 0.8 0.2 0.0 0.6 0.0 1.7 0.4 0.6 53.4 2.3 0.5 0.0 0.1 3.5 5.5 0.1 0.0 16.8 0.1 0.0 2.3 0.0 0.2 0.8 1.1 1.4 0.0 734.7 7.7 5.8 0.0 2.8 1.8 5.5 22.9 0.2 2.7 0.7 9.8 0.8 836.5 1.0 0.1 2.6 0.0 0.0 0.0 0.2 0.1 0.1 0.0 1.5 1.3 1.3 0.0 0.5 0.4 23.5 0.0 0.4 0.0 0.8 1.3 4139.3 10.5 7.1 1.8 1.0 1.5 40.7 2.1 0.0 0.0 0.4 0.1 13.2 0.3 1.0 1.3 0.5 0.4 100.3 19.7 0.0 0.1 14.5 9.0 0.0 1.1 0.0 1.0 0.0 0.6 0.6 PDZK1IP1 "DD96, MAP17, SPAP" ENSG00000162366 "PDZK1 interacting protein 1" Q13113 1 47183582-47191044 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "kidney: 1047.0" "Cell type enriched" "Detected in many" 4 "Proximal tubular cells: 5516.6" "Cancer enhanced" "Detected in all" "renal cancer: 340.7" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "neutrophil: 6.6" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 6 "EFO-21: 148.8;RPTEC TERT1: 501.3" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA014907 Enhanced Approved "Nuclear speckles,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "Nuclear speckles" "HPA014907: AB_1855166" "unprognostic (2.97e-1)" "unprognostic (3.33e-2)" "unprognostic (1.03e-1)" "unprognostic (9.16e-2)" "prognostic unfavorable (6.92e-4)" "unprognostic (8.14e-3)" "unprognostic (2.32e-1)" "unprognostic (1.46e-1)" "unprognostic (2.65e-1)" "unprognostic (2.31e-1)" "prognostic unfavorable (3.45e-4)" "unprognostic (2.64e-2)" "unprognostic (7.90e-3)" "unprognostic (1.22e-1)" "unprognostic (2.07e-1)" "unprognostic (1.75e-3)" "unprognostic (1.89e-1)" 20.9 8.2 0.6 24.6 0.8 43.2 36.4 0.4 1.2 29.9 0.7 44.4 21.6 10.7 2.9 205.9 25.7 197.6 1.4 0.5 0.7 1047.0 6.8 29.5 0.4 0.4 0.5 0.7 99.9 0.0 1.1 3.9 0.7 12.1 30.9 0.0 203.4 8.6 1.6 153.1 66.4 3.1 0.4 3.7 63.4 1.4 0.9 1.9 1.5 0.6 60.2 20.0 66.6 0.4 54.8 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 41.5 0.0 148.8 0.0 0.0 0.7 0.0 0.5 0.0 0.6 0.0 0.6 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 2.9 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 2.6 501.3 0.0 0.0 0.0 0.5 4.3 0.0 0.0 1.4 0.0 0.0 0.1 1.2 0.1 0.4 0.3 0.6 0.3 0.1 0.1 0.0 0.0 3.4 0.3 0.6 1.1 0.2 0.0 0.0 0.0 1.7 0.4 0.2 0.0 6.6 0.7 0.1 1.5 1.1 144.5 0.6 0.8 0.4 1.2 0.5 0.7 0.4 0.5 0.7 0.4 0.9 0.4 1.6 76.9 47.4 0.0 31.2 14.1 13.3 489.8 7.4 0.0 152.9 105.5 0.1 303.1 413.3 233.6 0.0 0.1 1.7 118.8 414.8 1175.8 0.0 6.1 3.3 4.5 39.6 148.4 0.0 760.0 0.0 6.6 36.7 38.1 10.8 0.2 5.0 1.7 0.3 0.0 0.0 143.3 52.9 0.3 2.1 0.0 3.4 59.3 8.8 0.0 13.6 0.6 2.1 0.0 0.0 1115.2 91.0 0.0 0.1 38.9 106.2 5516.6 147.6 0.0 0.0 0.1 28.7 0.0 0.1 30.7 54.0 0.8 22.0 0.0 150.5 68.5 PHLDB3 FLJ40193 ENSG00000176531 "Pleckstrin homology like domain family B member 3" Q6NSJ2 19 43474954-43504935 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 42.0;skin 1: 43.5" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 58.0;Urothelial cells: 45.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA043425 Approved Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 22: Epithelial cell types - Mixed function" "Nuclear speckles" "Plasma membrane, Cytosol" "HPA043425: AB_10797142" "unprognostic (2.50e-2)" "unprognostic (4.22e-3)" "unprognostic (3.06e-2)" "unprognostic (4.13e-2)" "unprognostic (1.02e-1)" "unprognostic (5.22e-3)" "unprognostic (4.43e-1)" "unprognostic (1.93e-1)" "unprognostic (2.15e-1)" "unprognostic (3.60e-2)" "prognostic favorable (6.36e-6)" "unprognostic (4.62e-2)" "prognostic unfavorable (4.11e-5)" "prognostic unfavorable (5.77e-4)" "unprognostic (2.06e-1)" "unprognostic (2.05e-1)" "unprognostic (2.37e-1)" 3.7 9.2 6.3 5.6 5.5 3.5 6.4 3.9 6.4 14.4 8.9 6.1 5.0 5.3 1.1 42.0 8.0 6.1 5.7 5.1 7.8 8.1 13.9 5.6 7.7 4.5 3.8 12.7 8.0 4.2 10.5 3.1 5.8 14.8 1.7 0.8 15.6 3.7 3.7 43.5 6.6 1.9 2.8 6.6 6.3 30.1 4.5 6.2 5.0 1.0 6.8 8.2 22.4 11.3 6.9 7.2 3.0 7.4 2.6 5.3 19.1 4.9 4.3 4.8 3.3 7.3 7.2 4.1 15.2 3.0 3.8 8.0 2.1 8.6 0.9 9.9 6.8 4.6 7.4 8.8 6.5 1.8 8.5 4.5 10.7 5.1 3.1 3.7 4.3 10.2 8.3 6.1 2.4 11.0 7.2 0.4 1.8 16.6 5.8 8.3 3.9 2.8 2.3 23.3 0.1 6.4 6.3 13.5 6.2 1.8 9.7 5.8 5.4 3.1 8.2 3.8 4.7 15.8 18.8 4.7 2.9 3.4 5.3 0.2 2.3 0.3 2.4 1.4 1.8 2.2 2.2 1.8 4.4 2.4 3.2 3.0 0.5 1.8 0.1 5.1 2.3 1.7 6.3 5.5 3.9 6.4 5.1 7.8 4.5 3.8 5.8 2.8 4.5 11.3 2.7 0.0 1.7 2.6 17.1 29.1 27.2 11.6 31.9 1.0 10.0 8.0 1.9 8.6 7.6 9.2 0.0 18.5 7.6 7.1 1.9 5.5 11.3 12.9 9.6 4.6 3.0 1.7 5.1 2.4 4.5 7.3 4.6 9.8 5.7 3.2 4.6 12.6 3.6 0.0 7.0 4.3 8.2 2.8 34.7 8.9 3.7 11.2 5.4 11.2 6.7 4.1 7.2 4.0 2.0 2.1 4.7 3.4 11.6 22.0 10.5 8.5 12.7 1.9 6.6 8.6 10.9 28.2 4.8 37.7 38.4 58.0 14.3 4.6 3.7 45.1 PHYHD1 MGC16638 ENSG00000175287 "Phytanoyl-CoA dioxygenase domain containing 1" Q5SRE7 9 128920966-128942041 "Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 119.3;Muller glia cells: 139.3;Proximal tubular cells: 161.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 13.0" "Lineage enriched" "Detected in many" 5 "dendritic cells: 13.0" "Cell line enhanced" "Detected in many" "ASC diff: 46.5;ASC TERT1: 32.7;BEWO: 50.6;HSkMC: 28.3;RPTEC TERT1: 78.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012115 Approved "Nuclear speckles" NA NA 36000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles" "HPA012115: AB_1859448" "unprognostic (1.18e-2)" "unprognostic (9.51e-2)" "unprognostic (2.21e-1)" "unprognostic (1.09e-3)" "unprognostic (2.16e-1)" "unprognostic (1.17e-2)" "unprognostic (4.49e-2)" "unprognostic (5.37e-3)" "unprognostic (1.35e-1)" "unprognostic (3.18e-1)" "unprognostic (1.86e-2)" "unprognostic (3.70e-2)" "prognostic favorable (6.38e-10)" "unprognostic (1.10e-2)" "unprognostic (3.09e-1)" "unprognostic (2.14e-1)" "unprognostic (9.83e-3)" 28.2 25.7 41.9 3.2 39.9 8.4 34.6 37.9 40.8 39.8 41.7 24.4 2.3 33.8 38.3 25.6 28.5 13.2 35.1 36.3 46.9 49.9 78.7 23.1 4.5 48.1 51.9 39.1 70.2 15.6 15.5 9.6 46.5 36.8 3.8 41.8 40.0 30.0 29.3 43.7 12.4 15.4 48.1 14.7 33.4 7.2 47.9 6.8 43.0 12.8 4.6 25.9 25.6 48.7 0.2 0.5 0.4 0.8 46.5 32.7 50.6 3.7 0.0 3.4 6.0 1.8 0.5 0.7 0.4 3.0 0.3 0.7 0.4 0.3 2.9 0.5 5.4 0.1 6.7 18.0 15.1 0.8 0.6 28.3 1.0 0.4 0.2 0.2 0.3 0.3 0.3 1.2 24.3 0.4 0.5 0.7 17.0 0.2 0.2 20.5 9.7 0.3 78.9 0.7 1.1 0.4 0.5 0.3 0.3 11.4 4.7 0.6 1.3 0.7 2.1 0.7 0.5 0.4 0.9 20.7 0.3 0.4 0.7 1.3 0.2 0.2 1.3 0.3 0.3 2.8 0.4 0.5 1.7 0.7 1.8 1.9 0.8 2.2 0.4 13.0 0.3 0.5 41.9 39.9 37.9 40.8 36.3 46.9 48.1 51.9 46.5 48.1 47.9 48.7 8.5 32.1 34.3 51.6 3.7 22.0 63.2 26.8 57.5 9.4 40.0 46.9 19.8 10.0 31.0 33.1 29.2 58.8 3.4 0.7 119.3 11.4 0.4 27.0 26.0 9.5 1.2 12.0 1.2 15.8 30.0 34.5 7.7 53.8 0.0 42.8 31.8 82.2 10.7 3.3 0.8 2.4 4.1 3.2 5.5 4.2 68.6 3.1 12.4 5.6 0.1 139.3 4.1 1.0 0.7 14.2 0.5 66.2 2.6 19.3 0.0 161.5 14.6 67.5 52.6 48.1 17.8 0.9 3.9 32.7 24.3 30.9 2.7 44.6 1.4 35.0 PINX1 "FLJ20565, Gno1, LPTL, LPTS, MGC8850, Pxr1" ENSG00000258724 "PIN2 (TERF1) interacting telomerase inhibitor 1" 8 10725399-10839847 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 2.9;vagina: 5.5" "Cell type enhanced" "Detected in many" "Early spermatids: 37.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HaCaT: 1.9" HPA009065 Uncertain Approved "Nuclear speckles,Golgi apparatus" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 39: Non-specific - Basic cellular processes" "Nuclear speckles" "Golgi apparatus" "HPA009065: AB_1857390" "unprognostic (2.57e-1)" "unprognostic (6.34e-2)" 0.4 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.2 2.9 0.0 0.1 0.1 0.0 0.0 0.8 0.0 0.1 0.4 0.0 0.0 0.1 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.7 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 5.5 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.9 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 3.2 6.7 12.4 10.4 26.6 20.7 12.0 14.2 5.6 0.0 0.0 0.0 8.6 8.2 3.7 12.5 0.0 4.0 6.9 11.7 0.0 37.0 0.0 0.0 7.3 8.4 6.9 25.0 0.0 0.0 5.3 7.7 0.0 14.0 0.0 12.5 7.0 0.0 3.3 22.4 5.0 8.2 5.4 10.3 32.7 9.3 3.9 7.2 13.1 3.3 9.0 7.2 17.6 15.3 0.0 5.3 6.4 14.0 20.2 6.5 13.3 7.0 22.1 0.0 12.5 5.5 21.5 22.7 12.0 28.6 0.0 8.3 0.0 9.6 8.9 PLA1A ps-PLA1 ENSG00000144837 "Phospholipase A1 member A" Q53H76 3 119597875-119629811 "Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 138.4;parathyroid gland: 65.8;seminal vesicle: 67.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 14.7;Endothelial cells: 14.3;Hepatocytes: 26.0;Langerhans cells: 15.6;Peritubular cells: 14.3" "Group enriched" "Detected in many" 5 "liver cancer: 14.8;melanoma: 55.4;prostate cancer: 24.2;renal cancer: 21.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 18 "SK-MEL-30: 25.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059740 Approved "Nucleoplasm,Nuclear speckles,Cytoplasmic bodies" "Secreted in other tissues" NA NA 420000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles, Cytoplasmic bodies" Nucleoplasm "HPA059740: AB_2684118" "unprognostic (1.35e-1)" "prognostic favorable (2.81e-7)" "unprognostic (2.24e-2)" "unprognostic (3.46e-2)" "unprognostic (3.18e-2)" "unprognostic (1.94e-2)" "unprognostic (1.11e-2)" "unprognostic (2.43e-1)" "unprognostic (3.87e-1)" "unprognostic (1.43e-2)" "unprognostic (1.25e-1)" "unprognostic (9.09e-2)" "unprognostic (1.55e-3)" "unprognostic (9.53e-3)" "unprognostic (3.94e-2)" "unprognostic (1.67e-1)" "unprognostic (2.67e-1)" 4.9 0.7 12.1 3.5 11.3 0.3 3.4 11.6 16.3 4.7 26.8 2.7 1.1 4.7 138.4 1.5 5.7 2.8 4.9 12.5 12.0 7.7 39.6 21.2 15.6 13.2 12.3 1.1 3.7 65.8 1.7 9.8 13.2 9.1 2.5 1.0 3.5 67.2 16.2 0.8 3.5 8.8 13.4 1.0 4.4 3.7 14.7 1.6 6.9 3.1 8.7 3.9 1.9 12.4 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.8 0.3 0.5 0.1 0.0 0.2 0.0 0.0 25.0 0.0 0.0 0.0 1.3 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 12.1 11.3 11.6 16.3 12.5 12.0 13.2 12.3 13.2 13.4 14.7 12.4 6.5 0.0 1.7 0.0 0.0 0.6 0.5 0.4 0.6 0.0 0.1 0.1 2.8 2.8 1.0 14.7 0.0 0.2 0.1 0.0 1.9 4.7 6.6 0.1 0.1 14.3 1.8 0.0 0.2 2.2 0.0 1.6 0.0 0.9 1.3 0.7 7.9 26.0 1.6 0.0 0.1 0.1 0.0 1.0 15.6 3.2 0.3 5.4 1.8 4.7 4.2 0.0 0.0 0.0 0.0 1.3 0.6 14.3 0.0 0.5 0.0 5.1 7.5 0.1 0.0 0.9 5.9 0.0 0.2 0.0 0.6 1.9 0.1 0.0 0.1 0.2 PLAG1 ZNF912 ENSG00000181690 "PLAG1 zinc finger" Q6DJT9 8 56160909-56211324 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Horizontal cells: 32.0;Microglial cells: 28.1;Rod photoreceptor cells: 27.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 16.0;ASC TERT1: 20.9;hTERT-HME1: 15.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA072290 Supported "Nucleoplasm,Nuclear speckles,Centrosome,Cytosol" NA NA "Cluster 30: Non-specific - Translation" "Cluster 77: Retina - Visual perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nuclear speckles" "Centrosome, Cytosol" "HPA072290: AB_2686508" "unprognostic (1.89e-2)" "unprognostic (1.93e-2)" "unprognostic (1.22e-3)" "unprognostic (1.63e-4)" "unprognostic (6.81e-2)" "unprognostic (1.07e-1)" "unprognostic (5.63e-3)" "unprognostic (8.56e-2)" "unprognostic (1.18e-1)" "unprognostic (7.99e-2)" "unprognostic (3.42e-2)" "unprognostic (1.97e-1)" "unprognostic (1.32e-3)" "unprognostic (2.83e-2)" "unprognostic (3.94e-1)" "unprognostic (1.21e-2)" "unprognostic (6.14e-2)" 0.7 1.4 0.8 1.0 1.2 0.9 0.9 2.5 1.1 3.0 0.6 0.8 1.4 1.4 4.1 0.7 3.1 0.7 3.1 0.7 1.0 1.3 0.3 1.9 1.8 1.5 1.4 4.9 0.8 1.2 3.8 1.6 1.8 1.3 0.6 7.7 3.0 1.8 0.4 1.4 2.3 0.4 1.2 2.6 1.3 2.4 1.3 2.8 1.3 1.4 2.3 1.3 3.0 2.0 2.0 0.0 11.9 0.1 16.0 20.9 3.7 5.4 6.9 2.5 1.1 0.8 6.2 0.2 5.1 2.9 0.7 0.4 3.4 7.1 2.5 0.2 7.4 8.0 0.8 1.8 3.3 2.5 2.3 14.9 3.9 1.4 15.6 6.9 4.7 5.3 3.4 0.1 5.3 0.1 0.7 4.7 3.4 0.5 1.8 6.1 0.8 4.9 3.2 0.7 0.1 0.0 0.1 0.1 0.4 8.0 0.1 2.4 7.2 3.6 4.6 5.9 1.4 1.8 1.5 2.9 4.1 0.9 1.0 0.6 0.0 0.4 0.1 0.0 0.1 1.3 0.4 0.2 0.0 0.7 1.8 1.8 0.4 0.3 0.2 0.1 0.1 0.4 0.8 1.2 2.5 1.1 0.7 1.0 1.5 1.4 1.8 1.2 1.3 2.0 2.6 6.4 3.2 2.9 13.0 1.0 2.5 6.2 1.8 23.6 1.6 0.6 12.2 4.3 6.7 5.5 25.0 8.3 2.0 1.0 0.0 0.7 6.2 3.0 2.3 3.7 5.4 5.0 16.8 1.3 4.2 4.0 2.6 4.2 1.3 0.4 15.7 0.7 5.8 32.0 12.3 3.6 6.1 2.9 2.2 6.7 15.2 2.8 16.0 28.1 1.2 16.3 4.1 2.0 19.2 1.4 4.1 10.1 6.3 5.0 5.1 0.8 9.1 27.8 0.0 2.4 1.4 9.0 8.8 1.1 0.9 7.1 4.5 0.9 3.6 12.9 PLEKHN1 DKFZP434H2010 ENSG00000187583 "Pleckstrin homology domain containing N1" Q494U1 1 966482-975865 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 54.9;skin 1: 46.0;vagina: 24.2" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 29.6;Pancreatic endocrine cells: 38.5;Prostatic glandular cells: 37.9;Squamous epithelial cells: 19.2;Urothelial cells: 52.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 15.1;HaCaT: 26.0;SK-BR-3: 16.6" "Not detected" "Not detected" HPA031742 Uncertain Approved "Nuclear speckles" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Nuclear speckles" "HPA031742: AB_10670704" "unprognostic (2.72e-3)" "unprognostic (8.05e-3)" "unprognostic (9.03e-2)" "unprognostic (4.47e-2)" "unprognostic (7.50e-4)" "unprognostic (2.93e-2)" "unprognostic (1.38e-2)" "unprognostic (1.78e-1)" "unprognostic (3.24e-1)" "unprognostic (1.01e-2)" "unprognostic (2.58e-3)" "unprognostic (2.08e-2)" "prognostic unfavorable (4.97e-5)" "unprognostic (9.98e-2)" "unprognostic (1.96e-1)" "unprognostic (2.05e-2)" "unprognostic (1.44e-1)" 0.4 1.6 0.0 0.7 0.1 0.4 1.7 0.0 0.1 11.5 0.0 0.6 0.9 0.4 0.3 54.9 0.9 0.7 0.2 0.0 0.0 2.1 0.9 1.1 0.3 0.0 0.0 0.1 1.1 0.5 0.3 0.4 0.0 3.6 0.1 0.0 10.2 1.2 2.1 46.0 0.8 0.1 0.0 1.2 2.0 0.4 0.1 0.1 0.7 0.0 1.6 7.5 24.2 0.0 15.1 1.4 0.0 1.0 0.1 0.7 2.5 6.8 1.7 4.1 1.1 2.0 11.3 0.0 3.2 3.0 5.7 26.0 0.2 4.5 0.7 5.0 1.0 0.0 5.6 3.3 0.6 0.3 0.2 0.2 3.8 2.9 1.6 3.7 0.5 0.0 0.3 4.0 0.2 8.3 0.0 0.3 0.5 2.4 11.0 0.1 0.0 5.6 4.3 4.2 0.1 0.1 7.5 16.6 1.0 0.4 3.2 0.0 3.2 5.3 2.3 0.5 4.6 3.2 0.1 0.1 6.8 2.5 3.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 3.2 1.1 0.0 1.9 4.6 29.6 5.0 1.8 0.5 3.8 1.8 0.9 0.0 6.4 0.0 0.0 7.1 1.0 1.9 0.0 13.8 0.0 3.0 1.1 0.7 0.0 0.0 0.0 14.0 2.0 0.9 3.1 8.2 0.0 0.0 0.7 0.3 1.1 3.3 0.0 0.0 8.2 0.3 1.4 0.0 0.0 0.9 1.8 0.0 1.9 0.2 0.0 0.0 0.0 38.5 3.3 0.0 2.5 37.9 0.0 0.1 5.2 0.2 0.0 0.2 1.0 0.0 0.7 19.2 17.3 9.9 2.8 0.0 0.1 52.9 PLRG1 "Cwc1, PRL1, Prp46, PRPF46, TANGO4" ENSG00000171566 "Pleiotropic regulator 1" O43660 4 154535005-154550400 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035931, HPA035932, HPA061486" Supported Enhanced "Nuclear membrane,Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 52: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nuclear speckles" "Nuclear membrane" "HPA035931: AB_2674868, HPA035932: AB_10673224, HPA061486: AB_2684536" "unprognostic (6.51e-2)" "unprognostic (5.66e-3)" "unprognostic (6.10e-2)" "unprognostic (1.32e-1)" "unprognostic (1.83e-1)" "unprognostic (1.61e-2)" "unprognostic (2.17e-2)" "unprognostic (1.88e-1)" "unprognostic (1.85e-2)" "unprognostic (2.88e-1)" "unprognostic (1.24e-1)" "unprognostic (1.74e-2)" "prognostic favorable (8.20e-5)" "unprognostic (2.92e-1)" "unprognostic (9.84e-3)" "unprognostic (1.64e-2)" "unprognostic (1.97e-1)" 29.4 21.9 22.8 24.9 26.3 31.1 38.7 26.0 24.3 32.8 20.8 30.9 24.8 34.0 28.6 33.9 34.2 24.8 25.9 22.6 32.6 38.1 43.8 27.3 35.2 30.5 26.8 34.0 19.6 41.1 16.0 28.3 30.7 27.4 34.2 26.4 25.8 33.7 31.7 26.4 25.8 44.6 33.5 27.7 26.4 21.4 25.3 40.4 38.0 39.5 51.2 34.8 22.7 39.2 73.2 58.6 73.7 79.4 85.1 73.5 62.3 91.6 111.2 121.9 98.9 69.3 62.7 79.1 45.7 109.1 80.3 52.4 97.2 122.1 134.5 80.2 48.7 95.1 45.1 67.8 87.0 96.0 76.4 79.7 110.8 144.6 112.6 73.0 106.1 85.3 98.9 98.2 107.2 52.3 73.9 45.7 56.1 57.5 62.7 72.2 38.5 48.2 84.8 46.1 43.0 48.6 55.9 59.3 91.7 69.4 57.1 66.4 69.3 72.4 81.9 64.6 82.9 50.9 72.0 100.6 68.1 45.6 98.8 53.0 37.0 29.7 41.6 43.3 49.9 47.0 43.5 45.7 47.6 36.2 45.9 43.2 9.4 67.6 63.9 46.4 55.7 49.4 22.8 26.3 26.0 24.3 22.6 32.6 30.5 26.8 30.7 33.5 25.3 39.2 26.9 25.6 18.1 29.0 26.9 16.3 31.2 98.7 18.2 26.2 19.6 22.9 24.7 20.0 50.7 22.0 12.5 49.1 23.6 18.0 15.6 48.0 31.7 22.7 33.0 27.5 27.1 30.5 23.6 34.7 37.9 30.9 17.9 20.3 45.7 27.0 16.1 26.8 34.2 62.2 21.7 15.9 73.2 19.3 12.0 5.8 28.0 17.2 14.2 17.8 36.8 31.2 28.8 14.1 25.0 32.6 20.9 35.0 21.8 14.9 33.7 35.0 45.2 21.4 19.7 31.2 40.8 36.4 30.2 25.0 17.3 44.3 26.9 36.8 22.3 20.6 PNISR "bA98I9.2, C6orf111, DKFZp564B0769, FLJ14752, SFRS18, SRrp130" ENSG00000132424 "PNN interacting serine and arginine rich protein" Q8TF01 6 99397629-99425331 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038796, HPA075076" Approved Supported "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 51: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "Plasma membrane, Cytosol" "HPA038796: AB_10672652, HPA075076: " "unprognostic (2.95e-1)" "unprognostic (2.29e-1)" "unprognostic (2.11e-1)" "unprognostic (9.72e-3)" "unprognostic (1.68e-2)" "unprognostic (8.55e-3)" "unprognostic (4.41e-2)" "unprognostic (1.58e-3)" "unprognostic (5.82e-2)" "unprognostic (4.32e-3)" "prognostic favorable (5.27e-4)" "unprognostic (1.47e-2)" "prognostic unfavorable (1.41e-4)" "unprognostic (3.43e-2)" "unprognostic (2.59e-1)" "unprognostic (8.89e-2)" "prognostic favorable (1.09e-4)" 68.2 68.8 56.9 52.0 55.4 106.8 75.3 78.4 89.8 103.1 67.5 114.5 51.4 79.7 93.6 51.8 93.2 38.2 84.6 54.3 56.4 67.1 62.2 74.4 78.7 56.7 54.7 123.0 66.0 38.4 112.0 36.4 52.9 91.2 49.4 102.1 76.6 48.1 89.4 64.1 94.1 49.4 49.3 90.6 77.1 39.4 56.9 51.4 114.5 31.2 54.9 81.6 80.3 60.1 26.7 19.5 98.8 72.0 35.3 46.8 45.8 44.1 22.8 25.6 29.9 33.3 49.2 85.8 26.6 25.3 28.7 41.9 49.3 33.3 45.2 75.0 48.8 52.6 105.0 30.6 22.2 73.0 67.9 51.8 50.0 27.4 37.5 95.7 34.2 44.8 59.3 52.5 31.3 25.2 31.8 71.2 55.2 24.5 15.3 62.1 29.6 32.4 47.1 47.1 43.4 51.9 21.7 23.6 35.3 75.4 32.8 58.6 45.0 25.2 28.9 25.7 37.2 35.9 24.3 70.5 37.5 68.3 27.0 12.3 10.8 11.9 12.5 6.4 13.0 19.3 12.0 10.4 5.0 25.8 17.9 16.6 30.0 23.5 7.7 19.6 12.4 3.7 56.9 55.4 78.4 89.8 54.3 56.4 56.7 54.7 52.9 49.3 56.9 60.1 175.8 185.9 237.6 356.2 375.8 195.3 357.3 250.5 165.6 546.2 143.9 192.5 121.2 137.2 215.7 178.4 446.2 158.3 336.4 152.4 74.3 130.8 17.0 132.2 185.7 210.7 247.8 194.4 241.5 104.5 102.1 240.1 100.9 140.5 190.5 344.5 135.7 109.4 99.7 498.0 257.4 129.6 199.4 128.0 236.8 47.9 593.3 152.1 167.2 193.9 261.6 223.6 375.9 270.4 252.6 133.1 176.2 441.2 209.8 293.6 205.8 58.6 179.6 419.9 249.8 288.7 236.3 342.6 181.3 115.5 173.6 180.9 283.8 363.3 151.3 352.4 PNN memA ENSG00000100941 "Pinin, desmosome associated protein" Q9H307 14 39175183-39183220 "Predicted intracellular proteins, Transporters" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, DNA-binding" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001378 Supported Supported "Nuclear speckles" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 18: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "HPA001378: AB_1079648" "unprognostic (9.28e-3)" "unprognostic (5.07e-2)" "unprognostic (5.46e-2)" "unprognostic (3.91e-1)" "unprognostic (7.38e-3)" "unprognostic (7.40e-2)" "prognostic unfavorable (5.79e-4)" "unprognostic (1.65e-2)" "unprognostic (1.67e-3)" "unprognostic (3.75e-2)" "unprognostic (3.70e-2)" "prognostic unfavorable (2.44e-4)" "unprognostic (1.51e-3)" "unprognostic (1.25e-1)" "unprognostic (1.53e-1)" "unprognostic (1.00e-1)" "unprognostic (4.30e-2)" 57.8 60.6 42.7 68.0 46.6 135.9 60.2 50.6 48.1 82.2 77.8 83.1 56.5 81.5 129.5 74.0 77.0 41.8 54.9 42.9 51.4 87.6 124.8 61.4 87.6 47.5 45.1 84.5 78.5 40.8 90.7 53.8 47.2 83.8 63.1 76.0 65.6 48.4 59.9 67.7 90.5 48.0 43.9 103.6 70.7 58.5 47.1 65.6 88.4 27.0 69.5 69.2 73.3 50.9 152.4 72.0 193.2 94.0 45.5 37.4 141.4 116.6 35.4 82.4 81.2 112.3 232.6 229.1 72.7 53.2 69.7 156.4 153.3 85.5 138.5 105.1 109.0 158.6 243.7 246.0 39.1 201.0 107.6 55.8 73.5 80.1 65.1 115.5 57.3 119.0 149.1 128.2 65.8 122.6 145.5 170.3 126.6 76.2 114.3 188.4 137.0 64.2 65.6 219.3 93.8 50.5 126.2 90.5 69.1 133.2 114.4 117.5 92.7 115.9 90.9 52.7 142.2 102.5 87.8 194.0 59.5 167.3 70.6 9.2 13.7 22.0 17.0 11.4 16.1 22.2 12.1 10.9 11.8 25.5 17.2 16.6 27.6 15.4 16.4 22.1 14.2 6.1 42.7 46.6 50.6 48.1 42.9 51.4 47.5 45.1 47.2 43.9 47.1 50.9 105.6 192.3 125.0 40.8 170.5 126.2 244.5 84.4 153.1 203.1 77.5 87.5 63.4 61.5 164.8 60.7 56.3 113.2 230.9 129.3 35.2 89.4 59.0 155.0 178.9 127.9 136.2 121.1 33.1 58.3 100.0 117.1 101.9 289.4 142.5 273.5 69.3 67.8 62.3 153.1 35.6 96.6 71.2 69.3 72.5 53.7 156.3 93.9 49.8 25.3 89.2 138.0 193.6 41.2 54.6 76.7 126.3 151.6 116.7 172.1 82.9 28.9 111.7 172.4 151.2 166.2 161.3 212.8 149.3 145.0 112.0 99.6 170.6 211.8 123.7 245.4 POLDIP3 "KIAA1649, PDIP3, PDIP46, SKAR" ENSG00000100227 "DNA polymerase delta interacting protein 3" Q9BY77 22 42583721-42614962 "Predicted intracellular proteins" "mRNA transport, Translation regulation, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 129.3;Late spermatids: 469.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018419, HPA048790" Approved Enhanced "Nuclear speckles,Cytoplasmic bodies" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nuclear speckles" "Cytoplasmic bodies" "HPA018419: AB_1856928, HPA048790: AB_2680522" "unprognostic (2.00e-1)" "unprognostic (1.55e-1)" "unprognostic (1.32e-1)" "unprognostic (7.05e-3)" "prognostic favorable (7.79e-4)" "unprognostic (2.82e-1)" "unprognostic (1.17e-2)" "unprognostic (5.44e-2)" "unprognostic (8.16e-2)" "unprognostic (4.49e-3)" "unprognostic (2.48e-1)" "unprognostic (5.96e-2)" "prognostic favorable (3.36e-4)" "unprognostic (3.73e-2)" "unprognostic (3.11e-1)" "unprognostic (1.15e-1)" "unprognostic (2.19e-1)" 25.9 36.5 51.7 26.3 56.0 68.2 33.3 52.5 54.9 43.2 45.5 36.7 25.8 40.5 34.7 42.6 53.2 24.0 34.4 50.2 51.1 40.6 33.2 36.3 36.2 59.2 54.1 91.1 35.9 34.4 35.6 32.6 53.3 41.3 29.3 30.1 37.7 33.4 34.9 39.1 31.8 35.4 50.6 38.6 44.4 30.8 54.1 48.6 37.6 34.5 46.4 34.8 34.3 58.1 43.7 43.7 96.3 45.4 42.7 48.7 61.7 49.0 41.1 73.6 54.6 51.6 29.5 73.3 30.8 58.2 34.9 49.5 101.0 55.8 57.1 35.6 74.9 58.4 50.8 53.6 39.5 91.9 57.5 33.8 62.5 54.1 56.0 61.4 52.5 54.1 63.7 47.0 58.8 48.5 76.3 65.3 53.5 56.4 40.5 96.5 87.7 49.5 61.4 27.9 31.5 27.2 59.6 51.1 53.0 56.2 47.4 67.4 48.3 46.7 56.0 31.8 50.1 45.3 59.5 67.1 37.8 56.0 67.4 23.3 36.9 29.8 30.9 34.8 32.0 26.9 27.3 26.3 41.9 26.2 29.7 27.1 21.2 28.6 30.9 21.5 31.0 38.7 51.7 56.0 52.5 54.9 50.2 51.1 59.2 54.1 53.3 50.6 54.1 58.1 15.8 19.2 15.1 10.4 28.6 19.6 23.7 13.1 22.2 30.1 23.0 20.6 13.3 17.2 16.0 20.2 20.9 36.5 23.1 22.9 21.5 29.1 129.3 22.9 20.7 18.9 19.2 25.6 7.1 24.9 39.7 23.2 21.4 23.4 24.1 18.8 16.1 19.0 22.2 25.2 8.8 15.8 16.2 25.7 17.9 469.0 21.8 19.9 19.6 18.7 40.3 23.6 22.6 11.6 17.4 26.4 21.2 24.8 24.5 37.2 19.2 20.3 19.5 17.1 46.0 19.3 18.5 33.0 34.5 22.9 17.6 52.1 23.0 22.6 19.0 28.6 POLI "RAD30B, RAD3OB" ENSG00000101751 "DNA polymerase iota" Q9UNA4 18 54269517-54321266 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, DNA synthesis" "DNA-binding, DNA-directed DNA polymerase, Mutator protein, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 117.4;Spermatocytes: 80.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012000, HPA064696" Enhanced Supported "Nuclear speckles,Cytoplasmic bodies" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" "Cytoplasmic bodies" "HPA012000: AB_1847786, HPA064696: AB_2685325" "unprognostic (1.64e-1)" "unprognostic (5.79e-3)" "unprognostic (9.72e-3)" "unprognostic (4.92e-2)" "unprognostic (3.04e-1)" "unprognostic (4.46e-2)" "unprognostic (1.31e-1)" "unprognostic (1.05e-2)" "unprognostic (4.04e-3)" "unprognostic (2.22e-2)" "unprognostic (2.07e-3)" "unprognostic (1.30e-3)" "unprognostic (1.55e-1)" "unprognostic (4.05e-2)" "unprognostic (1.26e-1)" "unprognostic (1.52e-2)" "unprognostic (6.99e-2)" 21.2 9.2 7.6 7.2 10.6 7.0 18.2 7.4 9.2 13.8 4.8 9.5 7.8 15.0 14.4 7.2 11.3 9.6 10.7 5.7 8.5 14.4 7.5 10.0 9.6 9.5 8.0 16.7 13.4 15.8 11.5 14.8 8.3 14.1 8.6 25.4 8.2 14.6 6.3 7.5 6.6 11.5 8.6 9.4 9.7 38.0 8.5 14.6 31.4 5.6 8.4 9.4 8.7 12.9 12.0 4.3 31.4 19.1 10.3 20.1 10.2 9.7 20.6 10.9 18.0 3.2 11.1 5.6 3.1 14.2 11.1 9.6 7.4 11.1 12.2 13.7 3.7 7.1 5.2 8.3 16.9 11.4 5.5 21.9 16.4 9.5 19.6 24.5 23.4 9.1 4.9 15.6 18.3 9.6 8.2 9.9 10.8 3.0 4.7 5.1 6.4 14.1 12.3 15.9 14.6 14.9 6.9 6.0 10.1 20.2 22.1 5.1 11.3 20.4 5.5 3.1 8.2 12.6 3.0 7.9 14.5 10.0 15.1 4.0 6.3 6.7 4.6 3.5 4.3 5.1 4.8 4.8 6.1 6.5 7.0 4.0 3.9 4.9 3.7 4.8 6.1 3.9 7.6 10.6 7.4 9.2 5.7 8.5 9.5 8.0 8.3 8.6 8.5 12.9 8.7 25.6 16.4 24.5 5.0 2.5 8.0 9.1 10.8 15.3 12.1 10.0 10.5 2.8 9.6 5.5 10.4 33.5 4.7 1.8 9.8 9.0 117.4 14.4 12.3 8.0 6.1 5.0 16.5 6.2 16.6 11.0 9.2 10.3 13.3 13.9 8.9 6.1 9.2 3.3 20.3 4.7 8.2 5.9 2.5 25.4 19.9 6.2 7.2 26.2 8.2 18.7 7.2 28.6 43.5 6.2 2.6 18.0 3.3 4.7 3.7 15.6 20.6 23.6 32.9 13.9 9.6 80.1 31.4 4.9 2.6 27.9 6.4 11.7 4.3 3.1 POLR2D RPB4 ENSG00000144231 "RNA polymerase II subunit D" O15514 2 127843553-127858155 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 74.3" "Cell type enhanced" "Detected in all" "Late spermatids: 170.2;Spermatocytes: 86.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034694, HPA046092" Approved Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Nuclear speckles" "HPA034694: AB_2674284, HPA046092: AB_10963049" "unprognostic (3.57e-2)" "unprognostic (3.76e-2)" "unprognostic (2.59e-1)" "unprognostic (2.54e-2)" "unprognostic (2.77e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (8.91e-4)" "unprognostic (2.51e-1)" "unprognostic (7.95e-3)" "unprognostic (2.64e-3)" "unprognostic (1.97e-1)" "unprognostic (2.51e-1)" "prognostic unfavorable (2.79e-4)" "unprognostic (3.66e-2)" "unprognostic (6.57e-2)" "unprognostic (1.17e-1)" "unprognostic (2.38e-1)" 12.3 10.4 7.2 14.4 9.8 32.4 11.9 9.6 8.3 9.4 7.3 12.0 9.7 10.3 8.0 12.3 10.6 8.4 10.0 7.5 8.7 8.8 19.2 10.2 19.7 8.0 8.9 15.0 14.7 10.4 8.3 15.9 8.3 9.5 14.7 8.1 8.4 9.2 29.3 11.3 9.3 15.0 8.4 12.8 9.4 74.3 8.1 28.3 9.1 27.1 26.9 15.3 8.4 11.0 63.4 40.6 73.9 51.9 26.8 29.2 59.0 59.1 27.9 69.6 61.9 92.0 50.9 97.7 49.6 40.0 39.8 32.7 107.0 51.2 107.3 57.7 58.3 96.6 37.9 85.4 31.4 104.9 51.6 20.8 37.8 93.3 53.2 19.3 46.1 70.4 137.1 84.8 40.4 50.1 105.0 47.5 103.6 65.9 46.4 99.3 77.8 88.0 23.1 42.6 45.7 60.9 39.9 48.9 50.7 54.7 54.6 71.4 47.0 60.1 84.4 34.4 69.0 99.4 173.4 173.0 52.4 51.2 60.5 9.9 22.8 17.3 26.3 31.7 25.0 22.8 21.0 23.2 29.9 20.2 27.6 23.7 7.3 25.8 35.0 19.5 20.6 21.3 7.2 9.8 9.6 8.3 7.5 8.7 8.0 8.9 8.3 8.4 8.1 11.0 10.9 3.2 11.7 2.6 22.0 10.8 22.0 7.6 15.9 15.1 9.8 6.2 10.4 11.5 10.1 12.9 8.4 33.0 23.4 7.6 11.7 20.3 70.8 13.2 16.1 12.5 8.4 31.1 4.7 17.5 31.0 15.2 9.7 10.4 18.4 23.1 11.4 17.0 21.7 33.7 5.2 11.9 8.2 11.1 14.1 170.2 17.7 13.3 8.8 2.8 23.4 13.2 16.5 2.5 7.5 18.4 8.4 18.4 46.6 26.2 10.2 11.1 6.8 13.7 13.1 18.5 15.5 86.1 48.9 19.3 10.1 26.7 17.1 31.5 14.0 18.9 POLR3B "C128, FLJ10388, RPC2" ENSG00000013503 "RNA polymerase III subunit B" Q9NW08 12 106357748-106510198 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RNA polymerase related proteins" "Antiviral defense, Immunity, Innate immunity, Transcription" "Nucleotidyltransferase, Transferase" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 24.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036466 Supported Approved "Nuclear speckles" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nuclear speckles" "HPA036466: AB_10671842" "unprognostic (1.17e-1)" "unprognostic (1.52e-1)" "unprognostic (4.80e-2)" "unprognostic (1.37e-2)" "unprognostic (1.13e-1)" "unprognostic (2.73e-1)" "unprognostic (4.21e-2)" "unprognostic (1.12e-1)" "unprognostic (1.33e-1)" "unprognostic (3.36e-2)" "unprognostic (6.11e-2)" "unprognostic (5.09e-2)" "prognostic favorable (1.21e-4)" "unprognostic (1.54e-1)" "unprognostic (1.46e-1)" "unprognostic (8.73e-2)" "unprognostic (9.24e-2)" 4.5 8.7 3.1 4.8 4.4 5.2 5.0 4.3 4.6 4.7 3.7 5.3 4.2 4.6 5.2 8.6 5.1 3.6 5.8 3.4 2.9 6.8 9.0 4.7 4.1 2.2 2.3 7.5 4.9 11.1 2.4 6.7 2.3 5.6 5.7 6.2 4.7 4.0 6.5 11.0 3.4 5.4 2.7 3.3 5.4 6.1 3.2 4.7 6.0 8.3 5.6 4.9 4.3 3.6 16.2 7.6 16.4 7.8 13.9 13.1 22.9 21.9 13.0 15.2 11.6 14.0 4.4 20.6 7.7 14.2 5.6 14.8 19.5 19.2 18.5 16.6 13.1 15.7 10.1 12.0 9.2 26.1 17.0 11.7 13.4 15.1 17.3 10.3 11.5 9.8 24.5 6.5 11.2 12.0 19.1 8.7 17.8 11.9 28.5 11.6 9.8 13.5 8.6 21.8 17.3 9.6 13.6 18.2 13.4 10.8 17.0 7.9 11.0 8.3 10.0 13.6 13.1 8.1 22.4 30.3 3.8 15.9 9.2 5.6 2.0 1.5 2.0 2.2 2.7 2.1 2.2 2.2 2.6 1.3 3.0 1.9 1.3 2.1 2.2 0.9 2.7 1.7 3.1 4.4 4.3 4.6 3.4 2.9 2.2 2.3 2.3 2.7 3.2 3.6 2.4 0.0 9.2 14.4 4.7 1.8 1.7 4.5 4.6 6.0 3.4 3.7 10.3 2.8 7.0 5.5 6.2 11.0 3.8 3.8 1.9 5.1 7.1 3.9 7.0 3.3 4.2 3.8 22.3 4.6 9.3 4.4 9.2 3.9 5.1 4.8 3.6 11.0 3.1 3.3 24.1 5.6 2.0 1.6 0.3 5.2 3.7 2.4 3.6 9.4 1.0 2.4 2.1 17.1 22.4 3.8 1.1 4.9 4.9 1.5 1.7 3.4 7.2 7.2 6.6 6.9 4.1 16.5 10.9 8.9 3.0 7.4 4.1 7.2 5.1 1.2 POMP "C13orf12, HSPC014, UMP1" ENSG00000132963 "Proteasome maturation protein" Q9Y244 13 28659104-28678959 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone "Ichthyosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026995 Approved Supported "Nuclear speckles" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nuclear speckles" "HPA026995: AB_1845546" "unprognostic (2.00e-1)" "unprognostic (3.56e-2)" "unprognostic (2.26e-1)" "unprognostic (3.15e-1)" "unprognostic (8.58e-2)" "prognostic unfavorable (2.05e-5)" "unprognostic (2.71e-3)" "unprognostic (2.50e-2)" "unprognostic (9.90e-2)" "unprognostic (4.35e-2)" "unprognostic (4.83e-2)" "unprognostic (4.93e-1)" "unprognostic (1.39e-3)" "unprognostic (1.70e-2)" "unprognostic (9.41e-2)" "unprognostic (1.03e-2)" "unprognostic (9.81e-2)" 78.9 71.6 77.5 62.9 78.5 66.4 66.7 82.1 101.1 45.1 77.8 66.6 57.0 44.4 78.9 68.7 43.4 46.2 126.3 78.1 83.6 94.1 110.9 65.6 65.4 82.2 83.4 32.9 46.6 51.7 41.7 100.3 83.2 46.6 66.3 56.2 45.1 50.7 175.6 48.5 58.4 57.2 83.6 61.2 54.9 70.0 81.0 64.6 51.4 114.6 70.1 74.0 46.9 86.3 103.4 124.9 129.9 153.1 145.3 161.3 120.3 232.1 203.8 225.5 179.5 245.7 228.7 181.7 136.3 178.6 241.7 150.3 170.7 179.3 307.5 137.7 131.9 171.7 130.1 191.1 203.0 209.6 136.0 131.2 181.9 162.5 149.5 122.3 181.6 139.7 222.2 72.5 291.5 182.5 178.4 295.6 226.1 319.0 146.1 169.6 199.3 122.2 259.6 160.7 152.1 117.1 104.0 147.4 162.2 161.5 103.1 238.5 166.2 108.7 111.2 172.3 195.5 61.5 118.5 255.3 129.2 139.8 243.6 146.4 155.3 101.7 99.9 210.8 88.7 136.4 101.6 113.2 190.8 137.6 71.8 101.9 135.1 95.3 213.9 223.4 132.3 165.2 77.5 78.5 82.1 101.1 78.1 83.6 82.2 83.4 83.2 83.6 81.0 86.3 527.4 131.4 114.2 17.3 218.5 409.8 345.1 1106.2 124.1 110.1 194.3 229.9 806.2 204.5 523.9 239.1 54.2 660.4 255.5 410.0 600.7 566.3 1156.6 266.7 235.8 486.2 228.7 271.5 23.4 699.5 974.0 281.8 128.9 293.0 207.3 181.6 434.1 538.7 780.7 97.6 22.4 315.0 585.9 431.0 673.7 533.7 201.0 407.1 300.6 29.0 612.6 294.7 228.6 13.6 26.1 755.1 414.0 233.6 228.1 443.5 491.8 922.5 472.8 121.8 322.1 193.8 494.6 625.5 240.3 230.1 416.3 972.4 202.7 234.7 335.5 494.3 PPIE "CyP-33, MGC111222, MGC3736" ENSG00000084072 "Peptidylprolyl isomerase E" Q9UNP9 1 39692182-39763914 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Isomerase, RNA-binding, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA019357, HPA020131" Approved Supported "Nuclear speckles" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 72: Non-specific - Transcription" "Cluster 43: THP-1 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" "Nuclear speckles" "HPA019357: AB_2670131, HPA020131: AB_1847405" "unprognostic (2.94e-1)" "unprognostic (4.32e-2)" "unprognostic (6.34e-2)" "unprognostic (6.97e-2)" "unprognostic (5.99e-2)" "unprognostic (8.41e-2)" "prognostic unfavorable (1.76e-4)" "unprognostic (3.52e-2)" "unprognostic (2.69e-1)" "unprognostic (3.88e-3)" "unprognostic (1.25e-1)" "unprognostic (9.29e-2)" "prognostic unfavorable (5.05e-5)" "unprognostic (5.86e-2)" "unprognostic (3.95e-1)" "unprognostic (9.06e-2)" "unprognostic (1.00e-1)" 26.0 27.9 22.3 16.1 22.9 18.5 26.8 22.7 26.5 31.4 20.2 41.1 18.3 33.8 24.9 31.8 35.0 18.1 33.3 22.3 22.8 33.0 33.7 23.3 27.2 22.6 22.0 36.7 40.2 23.8 27.7 20.7 22.9 32.3 22.5 20.9 26.2 23.6 43.1 29.5 29.2 25.4 23.7 32.7 31.7 41.8 22.3 20.6 29.1 30.3 28.2 36.4 29.5 24.6 24.5 34.4 37.2 25.7 40.9 36.9 14.3 40.8 42.7 58.7 56.4 32.8 64.8 68.4 52.2 47.9 34.5 32.8 57.1 52.3 68.8 41.1 38.4 75.6 37.4 9.7 50.9 68.4 36.3 32.8 47.2 53.9 21.0 42.0 54.5 52.8 74.8 39.5 46.6 24.7 34.2 42.1 39.9 49.7 31.5 41.4 28.4 38.4 37.8 37.2 47.7 42.3 43.8 31.5 28.4 49.7 40.9 155.8 35.8 36.3 35.3 48.4 57.1 55.8 66.4 52.5 27.0 86.4 52.3 38.3 62.8 32.6 83.9 64.8 82.8 107.5 89.4 83.8 74.1 109.2 103.5 82.4 6.0 123.2 70.0 63.8 101.3 122.5 22.3 22.9 22.7 26.5 22.3 22.8 22.6 22.0 22.9 23.7 22.3 24.6 28.2 32.1 36.7 10.7 37.0 24.9 43.1 69.8 23.9 25.9 30.3 47.5 31.8 21.5 62.1 33.1 14.6 62.5 39.3 22.8 66.5 57.5 29.2 34.6 27.7 28.7 28.8 38.3 7.7 48.4 59.3 34.0 16.3 23.4 55.2 44.1 37.9 31.1 56.1 23.5 8.8 32.9 40.7 33.4 26.9 76.3 29.8 30.0 39.2 8.4 46.8 34.0 58.7 8.0 13.6 40.0 24.1 45.1 31.7 32.0 39.3 69.8 63.4 29.7 59.2 23.3 40.1 76.1 51.4 24.5 26.3 34.8 36.6 36.3 35.9 32.9 PPIG "CARS-Cyp, SCAF10, SRCyp" ENSG00000138398 "Peptidylprolyl isomerase G" Q13427 2 169584342-169641406 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021788, HPA057469" Supported Supported "Nuclear speckles,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 1: K-562 - Erythropoiesis" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" Cytosol "HPA021788: AB_1847408, HPA057469: AB_2683445" "unprognostic (2.70e-1)" "unprognostic (2.17e-1)" "unprognostic (2.40e-1)" "unprognostic (2.04e-3)" "unprognostic (4.17e-2)" "unprognostic (3.49e-2)" "unprognostic (1.55e-3)" "unprognostic (3.66e-2)" "unprognostic (2.15e-3)" "unprognostic (3.15e-3)" "unprognostic (2.47e-2)" "unprognostic (2.28e-1)" "prognostic unfavorable (4.56e-4)" "unprognostic (5.23e-2)" "unprognostic (3.29e-1)" "unprognostic (3.41e-2)" "unprognostic (3.39e-2)" 26.0 23.2 23.1 28.4 22.1 54.2 27.5 28.8 58.6 27.6 22.9 26.3 26.6 28.8 31.5 27.5 23.6 22.0 25.6 21.5 29.9 29.2 47.1 24.7 36.9 24.6 25.6 26.5 21.2 32.6 25.8 28.0 24.3 27.9 26.0 29.3 26.5 22.9 27.6 25.4 29.7 21.7 22.9 32.3 27.4 20.1 23.7 36.1 29.9 26.2 35.4 26.3 26.5 25.9 56.4 25.5 70.8 35.9 35.4 42.5 63.7 58.9 42.3 45.0 45.9 66.3 58.9 94.8 52.5 44.1 55.5 50.5 56.6 48.4 65.6 68.0 45.7 129.9 36.7 88.3 34.4 136.8 58.9 36.6 54.0 58.5 64.6 40.6 50.4 53.5 142.7 76.2 49.5 43.5 101.0 81.9 100.8 45.3 25.1 90.7 71.7 90.5 53.9 81.2 60.5 41.2 63.4 47.2 68.9 52.9 44.2 78.7 52.7 53.9 43.7 38.4 52.6 41.1 65.3 126.8 38.5 68.1 54.1 31.9 22.5 36.7 22.8 25.1 26.7 32.9 30.9 29.2 18.2 38.4 33.4 27.6 40.4 21.1 31.4 30.0 26.8 17.0 23.1 22.1 28.8 58.6 21.5 29.9 24.6 25.6 24.3 22.9 23.7 25.9 159.7 221.2 175.1 53.5 188.8 151.4 191.4 185.9 101.3 204.6 120.8 156.1 148.4 107.2 169.5 93.8 54.2 170.0 160.1 91.6 80.3 103.1 11.0 104.6 142.3 141.1 104.8 163.5 82.4 103.3 177.0 142.4 66.8 126.3 179.1 115.8 121.7 181.2 151.7 220.4 81.8 135.8 116.0 130.3 126.5 15.6 142.0 129.6 110.3 46.9 152.4 137.6 133.9 53.8 69.7 93.9 118.0 146.7 130.1 161.8 121.1 113.8 132.2 109.1 164.3 150.2 193.9 276.4 183.8 108.3 172.8 205.5 166.7 147.1 149.9 167.7 PPP1R16B "ANKRD4, KIAA0823, TIMAP" ENSG00000101445 "Protein phosphatase 1 regulatory subunit 16B" Q96T49 20 38805697-38923024 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 71.6;lymphoid tissue: 41.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 119.4;Inhibitory neurons: 46.8;Oligodendrocyte precursor cells: 49.8;Oligodendrocytes: 238.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Daudi: 57.3;HMC-1: 59.2;HUVEC TERT2: 35.6;U-266/70: 96.7;U-266/84: 41.8;U-698: 38.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049571, HPA079512" Approved Supported "Nuclear speckles,Plasma membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "Plasma membrane" "Nuclear speckles" "HPA049571: , HPA079512: " "unprognostic (2.62e-2)" "prognostic favorable (2.11e-4)" "unprognostic (2.67e-3)" "unprognostic (3.35e-3)" "unprognostic (2.19e-1)" "prognostic favorable (7.87e-5)" "unprognostic (1.13e-1)" "unprognostic (4.17e-2)" "unprognostic (4.31e-2)" "unprognostic (6.28e-2)" "unprognostic (4.09e-3)" "unprognostic (4.77e-2)" "unprognostic (3.45e-2)" "unprognostic (8.53e-2)" "unprognostic (3.75e-2)" "unprognostic (1.73e-1)" "unprognostic (7.90e-2)" 13.2 2.9 36.5 19.3 71.6 17.7 8.2 26.1 61.1 3.2 5.1 4.6 3.6 3.4 1.5 3.1 5.8 5.3 5.2 49.3 22.3 27.7 2.4 7.9 37.7 27.8 34.7 1.1 1.5 0.8 2.2 3.7 27.1 1.6 5.1 3.7 2.0 1.9 3.6 1.5 18.0 7.2 24.3 18.1 5.6 0.7 35.7 18.2 3.4 5.7 41.9 6.0 1.6 52.1 0.1 0.7 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 57.3 0.8 0.0 0.9 0.1 1.0 0.1 0.0 1.4 0.2 4.4 0.0 0.0 0.0 0.2 59.2 0.0 0.1 0.0 0.0 0.0 35.6 7.6 1.0 11.9 0.0 0.0 7.4 9.7 7.9 0.1 0.0 5.0 0.0 0.0 0.0 0.0 17.7 19.7 0.0 0.0 0.0 0.7 0.0 3.1 5.5 0.0 0.9 0.0 0.0 96.7 41.8 38.3 0.0 0.0 0.1 0.0 0.2 2.5 3.4 0.5 1.8 5.3 2.3 3.3 0.7 3.3 1.3 1.8 0.0 2.9 0.9 3.3 2.6 1.1 36.5 71.6 26.1 61.1 49.3 22.3 27.8 34.7 27.1 24.3 35.7 52.1 29.3 3.2 3.0 1.3 33.6 1.0 0.0 0.8 0.6 2.3 0.5 0.5 23.5 1.5 4.0 0.0 0.0 0.0 34.0 0.3 0.0 0.0 1.9 0.2 0.2 18.7 0.0 2.7 119.4 0.0 0.0 1.6 4.1 0.3 3.8 0.0 38.6 0.3 0.1 37.0 46.8 0.1 0.0 3.1 3.6 1.5 0.0 3.8 8.8 23.4 20.5 0.3 11.3 49.8 238.0 0.0 0.1 0.0 29.3 0.0 0.0 17.4 3.6 0.3 0.0 0.3 1.0 0.0 0.3 0.3 1.3 0.0 37.4 0.0 0.2 0.3 PPP1R8 "ard-1, ARD1, NIPP-1, NIPP1, PRO2047" ENSG00000117751 "Protein phosphatase 1 regulatory subunit 8" Q12972 1 27830782-27851676 "Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" "DNA-binding, Endonuclease, Hydrolase, Nuclease, Protein phosphatase inhibitor, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027406, HPA027417, HPA027452" Enhanced Enhanced "Nucleoplasm,Nuclear speckles" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nuclear speckles" Nucleoplasm "HPA027406: AB_1854488, HPA027417: AB_1854489, HPA027452: AB_1854490" "unprognostic (5.61e-2)" "unprognostic (2.55e-1)" "unprognostic (4.42e-3)" "unprognostic (3.76e-2)" "unprognostic (2.00e-2)" "unprognostic (9.09e-3)" "prognostic unfavorable (2.19e-5)" "unprognostic (4.82e-2)" "unprognostic (2.14e-3)" "unprognostic (2.20e-1)" "unprognostic (3.16e-2)" "unprognostic (9.16e-2)" "unprognostic (6.26e-2)" "unprognostic (8.08e-2)" "unprognostic (2.91e-2)" "unprognostic (4.86e-2)" "unprognostic (2.58e-2)" 24.0 17.1 23.7 23.8 26.3 38.8 27.2 26.0 27.8 25.1 20.8 23.3 19.6 28.4 21.3 26.1 26.7 20.8 23.8 22.9 25.1 19.6 21.5 21.1 35.5 25.0 25.0 33.0 20.7 25.2 15.8 25.2 25.7 21.0 25.1 28.0 18.9 25.7 25.3 23.2 21.4 30.6 26.0 25.9 19.7 24.0 24.2 41.0 25.2 37.0 36.4 29.5 20.5 30.5 57.8 40.0 85.3 55.8 52.6 54.7 48.9 60.5 63.3 101.5 81.6 45.2 64.5 81.9 41.6 69.3 39.5 50.9 101.3 56.6 73.2 69.3 61.7 107.2 53.3 67.2 52.9 99.9 73.0 48.0 60.7 92.4 81.8 45.4 61.3 68.9 92.4 54.3 61.2 37.6 109.6 58.6 105.9 50.7 46.2 88.4 70.5 78.2 54.9 52.2 59.5 54.0 74.5 57.5 73.4 43.5 50.5 61.7 50.9 49.6 45.3 78.9 57.2 50.0 82.2 102.8 48.5 127.6 65.0 17.2 9.1 8.5 12.4 9.5 14.3 9.8 9.7 13.7 8.8 9.9 10.5 10.2 5.4 14.3 11.4 6.7 10.8 13.2 23.7 26.3 26.0 27.8 22.9 25.1 25.0 25.0 25.7 26.0 24.2 30.5 11.3 16.0 10.0 2.9 21.3 17.3 21.4 33.4 7.4 22.0 12.0 9.8 13.4 8.6 24.2 5.5 2.1 47.6 19.6 15.4 31.3 30.6 33.7 9.8 15.2 17.8 11.5 20.6 8.4 25.9 41.2 17.1 12.2 11.1 26.0 16.8 19.6 20.2 26.3 8.4 8.6 15.0 28.5 18.0 11.5 30.0 23.9 14.1 10.6 4.7 35.6 21.5 25.7 10.6 16.0 31.9 14.7 17.0 14.3 24.6 14.3 25.7 18.1 16.9 26.3 16.2 20.0 35.4 43.2 16.5 14.1 43.9 17.4 28.8 16.2 21.2 PPP4R3A "FLFL1, FLJ20707, KIAA2010, MSTP033, PP4R3, SMEK1, smk-1, smk1" ENSG00000100796 "Protein phosphatase 4 regulatory subunit 3A" Q6IN85 14 91457508-91510554 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002568, HPA063917" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Nuclear speckles, Cytosol" "HPA002568: AB_1079207, HPA063917: AB_2685153" "unprognostic (5.51e-2)" "unprognostic (2.93e-2)" "unprognostic (3.26e-1)" "unprognostic (1.40e-1)" "unprognostic (4.40e-2)" "unprognostic (9.95e-3)" "unprognostic (4.10e-2)" "unprognostic (5.71e-3)" "unprognostic (1.05e-1)" "unprognostic (8.34e-3)" "unprognostic (1.33e-1)" "unprognostic (3.85e-2)" "unprognostic (3.07e-1)" "unprognostic (1.13e-1)" "unprognostic (2.57e-1)" "unprognostic (1.57e-1)" "unprognostic (4.53e-2)" 19.3 13.5 14.4 18.2 14.5 50.0 19.6 16.6 15.2 19.1 16.2 21.2 17.2 20.0 15.9 21.4 20.4 12.3 16.2 12.6 13.3 18.3 23.7 20.2 28.3 13.6 14.2 22.0 19.8 16.8 14.8 17.5 13.7 18.4 18.5 10.9 20.8 13.1 24.5 25.4 24.4 15.0 12.7 24.1 20.6 22.3 14.5 27.4 17.7 16.7 25.4 19.5 19.4 16.9 24.5 41.4 34.1 27.1 22.5 20.9 60.9 23.2 21.4 24.5 24.6 35.2 32.1 63.1 30.2 19.2 15.0 27.8 36.6 28.9 39.8 52.0 19.7 32.5 25.7 24.5 26.3 59.1 33.1 15.1 50.4 19.7 31.1 20.1 26.7 29.4 33.5 36.2 33.1 52.1 42.8 38.0 31.2 46.5 29.8 54.0 40.6 26.5 30.3 41.5 41.6 25.4 35.3 77.0 32.5 33.6 39.4 37.8 28.0 19.2 20.6 21.1 26.8 36.0 67.0 69.3 25.2 31.8 34.7 6.2 1.9 2.9 4.9 2.6 6.6 4.6 4.5 4.4 2.1 7.4 5.6 4.8 2.5 9.0 3.7 5.0 6.9 2.6 14.4 14.5 16.6 15.2 12.6 13.3 13.6 14.2 13.7 12.7 14.5 16.9 44.1 32.1 48.3 0.0 83.0 0.0 46.7 0.0 58.1 27.9 35.9 23.5 0.0 32.9 30.3 46.0 20.9 33.9 91.8 21.1 29.4 21.2 13.0 86.9 46.5 33.3 13.3 47.5 0.0 25.1 29.0 27.3 45.3 70.7 20.2 39.8 28.9 51.8 25.8 32.0 0.0 28.2 0.0 48.7 0.0 8.5 37.6 70.7 0.0 0.0 41.8 21.0 44.3 0.0 0.0 27.8 25.7 42.5 75.8 56.6 37.3 23.5 16.8 27.3 26.3 45.9 27.1 91.0 59.9 58.0 0.0 44.3 80.1 33.0 25.8 75.2 PPP4R3B "FLFL2, FLJ31474, KIAA1387, PSY2, SMEK2" ENSG00000275052 "Protein phosphatase 4 regulatory subunit 3B" Q5MIZ7 2 55547292-55618880 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001233, CAB017185" Approved Supported "Nucleoplasm,Nuclear speckles,Centrosome" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Nuclear speckles" Centrosome "CAB017185: , HPA001233: AB_1080033" "unprognostic (9.60e-2)" "unprognostic (2.47e-2)" "unprognostic (5.77e-2)" "unprognostic (1.87e-2)" "unprognostic (6.34e-2)" "unprognostic (3.56e-1)" "unprognostic (2.66e-2)" "unprognostic (3.27e-2)" "unprognostic (8.27e-3)" "unprognostic (7.62e-2)" "unprognostic (1.07e-2)" "unprognostic (3.69e-1)" "prognostic unfavorable (6.03e-4)" "unprognostic (9.73e-2)" "unprognostic (1.45e-1)" "unprognostic (6.28e-2)" "unprognostic (2.77e-1)" 29.0 27.4 14.8 28.2 15.1 25.8 29.1 20.9 16.9 26.8 20.0 28.1 31.6 23.7 19.3 31.7 32.3 24.7 14.3 13.8 16.9 33.4 48.0 23.4 38.1 15.0 16.3 25.7 32.1 27.4 12.5 24.5 16.2 24.9 27.7 35.3 28.1 23.2 14.7 29.6 32.1 21.8 15.9 28.7 30.8 23.7 15.1 42.2 33.0 20.3 38.7 26.7 16.9 18.7 42.8 33.0 35.6 30.0 37.2 38.9 49.1 34.0 35.9 28.2 24.0 39.5 40.9 57.7 67.5 32.7 44.8 36.4 39.9 27.5 41.4 84.6 16.7 56.7 30.0 52.9 60.3 66.0 45.6 29.8 64.9 34.1 60.1 36.9 45.0 31.6 55.2 57.4 37.7 50.9 42.8 43.7 35.1 55.9 25.3 40.1 53.6 44.6 39.3 43.8 43.4 26.9 36.8 49.9 54.8 23.5 31.6 52.0 36.3 43.3 56.8 21.6 47.2 59.1 47.3 22.3 40.8 61.3 47.2 25.6 16.5 26.9 20.4 20.9 23.2 18.1 21.2 21.6 18.4 18.6 24.5 21.5 19.6 22.5 23.0 9.9 24.0 23.9 14.8 15.1 20.9 16.9 13.8 16.9 15.0 16.3 16.2 15.9 15.1 18.7 46.8 44.8 41.3 0.0 61.8 0.0 48.9 0.0 44.3 44.1 42.7 27.9 0.0 31.5 29.1 16.5 33.3 30.6 51.4 25.3 39.2 32.4 9.5 85.1 43.2 32.9 18.2 46.7 0.0 41.0 28.5 33.9 43.8 39.6 30.3 39.0 26.0 52.5 26.2 53.8 0.0 29.4 0.0 37.7 0.0 7.6 28.0 44.9 0.0 0.0 47.9 53.1 49.4 0.0 0.0 35.4 24.1 36.1 57.2 57.4 46.1 52.9 62.7 38.5 6.6 54.9 28.4 39.1 25.7 53.3 0.0 47.7 56.3 44.6 29.0 57.2 PQBP1 "MRX2, MRX55, MRXS3, MRXS8, RENS1, SHS" ENSG00000102103 "Polyglutamine binding protein 1" O60828 X 48890197-48903143 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Immunity, Innate immunity, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001880 Supported Enhanced "Nuclear speckles" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 2: Karpas-707 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear speckles" "HPA001880: AB_1079671" "unprognostic (7.25e-2)" "prognostic favorable (1.48e-4)" "unprognostic (5.98e-2)" "unprognostic (2.09e-2)" "unprognostic (2.73e-2)" "unprognostic (1.52e-1)" "unprognostic (1.78e-2)" "unprognostic (1.09e-2)" "unprognostic (1.10e-1)" "unprognostic (7.48e-2)" "unprognostic (4.33e-3)" "unprognostic (1.51e-1)" "prognostic unfavorable (2.68e-7)" "unprognostic (2.68e-1)" "unprognostic (2.52e-3)" "unprognostic (3.97e-2)" "unprognostic (5.70e-3)" 38.8 50.6 35.5 25.6 36.9 46.0 39.3 38.1 44.2 47.9 31.1 50.0 39.2 42.5 22.7 48.6 41.0 24.2 43.0 36.7 40.2 41.7 61.0 35.6 31.1 38.8 37.3 58.4 62.8 28.1 50.5 18.2 38.6 42.2 20.4 21.5 43.2 28.3 65.0 52.0 42.2 25.3 38.4 45.2 52.1 13.8 39.0 38.6 38.6 32.3 29.0 39.2 43.2 40.0 100.6 124.3 64.5 63.2 58.2 40.8 48.8 57.3 67.1 116.8 70.7 146.3 45.0 91.8 46.2 40.0 88.1 79.9 110.6 42.6 43.5 80.8 95.2 78.1 94.6 109.5 55.9 95.5 69.8 50.7 81.4 96.8 95.5 46.5 67.0 35.9 75.7 169.0 50.1 167.5 41.5 94.3 60.3 69.3 139.6 66.7 63.0 209.4 75.5 66.2 95.7 49.4 75.3 82.6 66.5 48.0 103.5 68.9 58.6 51.1 92.2 65.6 77.4 99.9 106.5 69.5 29.0 88.0 53.8 41.8 81.9 53.1 56.4 79.1 74.7 83.9 78.2 56.2 96.9 70.4 81.5 74.9 23.4 76.1 73.0 86.9 114.3 84.5 35.5 36.9 38.1 44.2 36.7 40.2 38.8 37.3 38.6 38.4 39.0 40.0 37.0 41.7 65.9 6.2 65.4 111.8 86.1 99.5 85.4 36.7 76.9 97.2 39.0 54.3 68.6 31.3 12.5 58.5 53.4 85.1 49.0 59.9 6.2 37.5 38.6 54.5 70.1 38.7 4.4 95.8 56.1 53.9 39.8 54.3 70.5 36.6 43.5 45.0 70.2 18.5 3.9 68.2 77.3 72.2 113.5 4.9 69.9 56.2 88.9 3.7 96.6 47.4 55.6 3.5 4.8 73.7 123.6 43.6 105.9 54.2 151.1 108.5 51.6 27.7 39.5 64.4 69.8 2.7 17.7 69.5 117.3 54.6 62.9 67.0 67.9 69.3 PRCC RCCP1 ENSG00000143294 "Proline rich mitotic checkpoint control factor" Q92733 1 156750610-156800815 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017151, HPA019463, HPA019481" Supported Enhanced "Nuclear speckles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 55: Plasma cells - Humoral immune response" "Nuclear speckles" "CAB017151: , HPA019463: AB_1855672, HPA019481: AB_1855673" "unprognostic (6.12e-2)" "unprognostic (2.68e-1)" "unprognostic (2.68e-3)" "prognostic unfavorable (5.55e-4)" "unprognostic (3.19e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (8.63e-4)" "unprognostic (3.03e-1)" "unprognostic (9.16e-2)" "unprognostic (3.27e-3)" "unprognostic (1.14e-1)" "unprognostic (6.80e-2)" "prognostic unfavorable (8.99e-15)" "unprognostic (1.72e-1)" "unprognostic (2.74e-1)" "prognostic unfavorable (3.72e-4)" "unprognostic (1.02e-2)" 31.9 31.8 43.4 29.7 45.2 41.9 31.4 44.5 50.4 32.4 42.3 36.6 27.0 34.5 23.1 39.7 29.7 23.0 37.6 45.7 42.0 36.7 34.2 29.6 36.3 43.3 42.8 30.9 29.0 34.7 28.1 29.0 43.7 33.5 22.5 26.6 30.4 24.1 63.4 43.2 30.9 27.3 41.3 37.4 31.8 27.0 43.3 37.5 31.0 34.4 30.7 32.6 32.2 46.9 79.1 67.3 51.6 59.5 42.5 33.8 89.8 53.8 52.8 59.3 50.8 106.2 65.0 80.6 90.4 43.1 34.1 80.3 74.7 57.0 45.3 101.6 97.4 59.1 47.4 68.4 52.5 81.9 66.6 48.1 64.7 51.5 46.6 45.7 55.2 52.5 99.7 72.1 41.8 140.2 94.1 94.6 124.9 108.9 82.0 81.6 45.7 108.7 62.5 74.0 91.6 163.4 57.0 140.6 92.4 84.4 102.7 129.8 51.1 59.3 61.9 66.0 89.6 184.6 298.5 124.1 58.7 52.2 56.1 46.9 28.6 57.4 27.5 29.9 26.5 24.0 24.7 30.0 32.5 27.6 24.0 25.2 27.7 30.2 37.1 38.9 27.1 26.0 43.4 45.2 44.5 50.4 45.7 42.0 43.3 42.8 43.7 41.3 43.3 46.9 22.2 9.6 16.4 12.7 32.0 52.4 38.2 52.1 46.1 19.8 31.1 24.4 13.0 18.6 29.4 20.2 22.9 63.1 36.0 27.2 21.5 39.4 13.5 21.4 21.9 30.2 34.3 16.6 15.9 32.2 63.4 28.7 24.5 23.2 17.1 28.9 25.4 16.0 44.0 28.6 14.4 26.9 40.7 22.6 27.4 10.4 30.4 28.4 21.4 9.4 44.9 16.9 30.9 18.1 25.4 35.5 34.2 28.6 48.8 43.8 29.8 29.9 21.5 19.8 32.9 32.2 29.2 43.3 46.2 39.6 51.3 101.1 30.3 32.4 29.4 39.2 PRDM7 ZNF910 ENSG00000126856 "PR/SET domain 7" Q9NQW5 16 90056566-90092072 "Predicted intracellular proteins" "Chromatin regulator, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8 "testis: 1.0" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 6.3;Spermatocytes: 14.3;Spermatogonia: 5.1" "Cancer enriched" "Detected in single" 30 "melanoma: 3.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 16 "REH: 3.8;SK-MEL-30: 2.6" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA059944 Approved Uncertain "Nuclear speckles" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 14: REH - Unknown function" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nuclear speckles" "HPA059944: AB_2684174" "unprognostic (3.98e-1)" "unprognostic (8.89e-2)" "unprognostic (8.02e-3)" "unprognostic (8.26e-2)" "unprognostic (9.01e-2)" "unprognostic (5.61e-3)" "unprognostic (1.05e-2)" "unprognostic (1.46e-1)" "unprognostic (5.73e-1)" "unprognostic (5.52e-4)" "unprognostic (1.36e-1)" "unprognostic (1.61e-1)" "unprognostic (4.03e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.5 0.0 0.0 0.0 0.2 14.3 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRKAA1 AMPKa1 ENSG00000132356 "Protein kinase AMP-activated catalytic subunit alpha 1" Q13131 5 40759379-40798374 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Autophagy, Biological rhythms, Cholesterol biosynthesis, Cholesterol metabolism, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism, Transcription, Transcription regulation, Wnt signaling pathway" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 292.5;Late spermatids: 478.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005050, HPA035409, HPA064946" Supported Supported "Nuclear speckles,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 31: Spermatids - Spermatogenesis" "Nuclear speckles" Cytosol "CAB005050: AB_562037, HPA035409: AB_2674613, HPA064946: AB_2685390" "unprognostic (2.07e-1)" "unprognostic (1.41e-2)" "unprognostic (2.51e-2)" "unprognostic (3.57e-2)" "unprognostic (3.97e-1)" "unprognostic (1.05e-1)" "unprognostic (3.51e-2)" "unprognostic (7.53e-2)" "unprognostic (1.66e-2)" "unprognostic (2.88e-1)" "unprognostic (3.34e-3)" "unprognostic (2.63e-1)" "unprognostic (2.82e-2)" "unprognostic (1.35e-1)" "unprognostic (1.60e-1)" "unprognostic (1.27e-2)" "unprognostic (1.10e-2)" 33.3 21.0 7.9 27.2 9.6 52.6 30.2 10.3 11.0 26.7 12.3 30.0 35.4 26.3 18.6 20.6 21.0 33.5 20.2 6.9 11.3 32.0 49.9 27.4 29.2 11.8 9.9 19.1 23.1 32.0 9.2 21.2 12.2 31.9 34.7 19.0 27.4 24.7 16.9 23.1 30.9 26.4 10.2 27.8 33.7 41.1 10.0 21.8 32.3 19.9 23.9 28.8 17.8 10.3 28.4 28.9 22.8 30.2 55.0 57.0 21.6 47.3 48.1 34.7 30.8 27.6 35.9 16.6 21.4 48.8 45.3 22.4 21.3 43.1 64.9 49.2 19.2 33.1 66.1 22.1 45.3 31.9 33.5 52.8 20.6 46.5 47.5 38.4 52.1 21.0 15.9 46.7 52.4 13.6 29.7 24.9 9.9 28.9 34.6 24.5 48.7 24.6 53.3 47.5 19.6 19.7 83.0 54.3 28.8 12.3 28.4 26.0 56.0 62.1 33.5 36.2 39.2 18.5 15.4 19.6 38.9 67.9 33.9 17.0 6.5 12.8 8.9 7.9 11.5 8.2 8.4 8.6 6.4 7.9 10.1 9.0 15.4 10.9 9.3 1.9 11.6 6.5 7.9 9.6 10.3 11.0 6.9 11.3 11.8 9.9 12.2 10.2 10.0 10.3 47.3 41.7 26.5 19.2 34.1 24.1 24.7 40.5 15.4 20.3 36.1 17.9 18.3 42.9 43.4 47.8 35.5 13.8 45.8 44.1 7.9 27.9 292.5 19.7 35.8 42.4 21.1 25.4 24.5 44.9 13.7 36.2 36.7 20.7 18.3 17.8 37.1 83.4 20.0 15.2 30.3 28.8 42.7 25.3 28.5 478.5 30.4 24.1 35.6 24.4 40.9 15.4 44.3 30.7 43.8 36.0 32.8 25.9 23.4 33.4 33.7 35.4 42.9 27.9 0.0 22.7 43.1 82.8 17.6 19.9 32.7 18.6 44.0 19.2 36.9 35.0 PRKAA2 "AMPK, AMPKa2, PRKAA" ENSG00000162409 "Protein kinase AMP-activated catalytic subunit alpha 2" P54646 1 56645314-56715335 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Autophagy, Biological rhythms, Cholesterol biosynthesis, Cholesterol metabolism, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism, Transcription, Transcription regulation, Wnt signaling pathway" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 40.8;skeletal muscle: 38.7;tongue: 36.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 328.5;Excitatory neurons: 109.4;Inhibitory neurons: 119.0;Oligodendrocyte precursor cells: 84.9;Rod photoreceptor cells: 115.5" "Cancer enhanced" "Detected in many" "renal cancer: 5.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 14.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044540 Approved Supported "Nuclear speckles,Golgi apparatus" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nuclear speckles" "Golgi apparatus" "HPA044540: AB_2678977" "unprognostic (4.17e-3)" "unprognostic (1.62e-2)" "unprognostic (4.17e-1)" "prognostic unfavorable (4.80e-4)" "unprognostic (9.35e-2)" "unprognostic (1.92e-3)" "prognostic unfavorable (5.30e-4)" "unprognostic (7.30e-2)" "unprognostic (3.94e-1)" "unprognostic (1.82e-1)" "unprognostic (1.97e-1)" "unprognostic (8.64e-2)" "prognostic favorable (4.95e-5)" "unprognostic (1.30e-2)" "unprognostic (4.52e-2)" "unprognostic (1.57e-2)" "unprognostic (1.85e-1)" 1.4 1.4 2.0 0.5 3.5 0.0 3.3 3.0 3.5 1.4 4.1 5.0 0.5 1.8 1.1 4.7 2.7 1.9 40.8 3.9 2.1 13.6 0.7 1.4 0.1 0.9 1.3 1.5 1.8 8.3 1.3 0.5 0.9 3.8 1.4 13.5 4.3 2.6 38.7 0.7 1.3 3.1 0.3 1.3 2.2 1.1 1.3 0.4 3.3 36.4 0.1 1.8 1.3 1.5 0.0 3.8 2.1 0.0 0.7 0.5 2.3 1.9 1.5 2.5 4.3 3.9 4.9 0.0 0.6 0.6 7.5 0.1 8.0 0.0 7.1 0.0 8.8 0.0 7.0 5.5 0.0 0.0 0.1 0.6 0.0 3.5 0.3 5.8 0.8 2.0 0.0 0.0 1.1 0.1 0.0 0.0 5.6 0.0 5.5 0.0 0.0 0.0 14.1 1.3 2.0 5.5 6.0 0.1 0.0 6.0 3.3 0.0 0.0 1.5 2.3 2.8 6.6 0.0 0.0 0.0 4.5 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 3.5 3.0 3.5 3.9 2.1 0.9 1.3 0.9 0.3 1.3 1.5 1.1 9.6 4.8 30.7 2.0 0.9 8.0 6.7 2.2 42.0 19.4 9.5 328.5 24.3 14.3 49.7 50.1 1.0 0.2 6.1 54.8 9.5 3.9 14.4 2.9 10.3 14.4 0.0 109.4 4.8 0.4 15.3 5.1 17.4 2.5 11.7 9.7 8.1 0.1 26.9 119.0 6.3 8.2 0.0 1.6 4.8 6.8 1.4 5.4 18.7 0.0 18.6 0.0 84.9 20.4 6.2 3.0 29.3 0.0 21.2 0.2 82.4 10.7 115.5 6.6 24.5 17.2 7.2 3.7 17.7 0.4 0.4 1.2 5.3 6.1 13.4 PRKN "AR-JP, PARK2, parkin, PDJ" ENSG00000185345 "Parkin RBR E3 ubiquitin protein ligase" O60260 6 161347417-162727775 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 28.3;tongue: 15.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Alveolar cells type 2: 4.8;Distal tubular cells: 19.6;Proximal tubular cells: 6.8" "Cancer enhanced" "Detected in many" "renal cancer: 3.3" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AN3-CA: 2.0;HEL: 4.1;HSkMC: 1.7;Karpas-707: 2.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB016257, HPA036012" Enhanced Supported "Nuclear speckles,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 39: Non-specific - Basic cellular processes" "Nuclear speckles" Cytosol "CAB016257: AB_628104, HPA036012: AB_2732471" "unprognostic (9.23e-2)" "unprognostic (3.29e-2)" "unprognostic (6.48e-2)" "unprognostic (2.69e-3)" "unprognostic (9.85e-2)" "unprognostic (5.85e-2)" "unprognostic (7.07e-2)" "unprognostic (1.12e-1)" "unprognostic (1.39e-1)" "unprognostic (2.68e-2)" "unprognostic (1.03e-3)" "unprognostic (8.16e-2)" "prognostic favorable (6.75e-12)" "unprognostic (9.93e-2)" "unprognostic (1.51e-1)" "unprognostic (5.24e-2)" "unprognostic (2.50e-1)" 3.4 3.3 4.1 0.1 3.6 0.3 1.9 0.4 5.7 1.3 0.6 2.7 1.2 1.6 1.2 3.2 1.2 1.5 9.1 4.6 1.8 5.2 1.2 1.0 0.5 1.0 1.9 2.8 1.2 2.3 1.8 0.4 1.6 1.2 0.6 1.5 1.3 1.4 28.3 2.0 1.0 1.2 1.0 1.0 1.9 5.3 1.9 0.5 1.3 15.9 0.3 2.5 1.0 2.4 0.0 0.0 0.3 2.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.5 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.5 4.1 0.1 0.6 0.3 0.0 0.0 1.7 0.0 0.0 0.2 0.3 0.0 0.2 0.2 2.2 0.0 0.2 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.7 0.0 0.0 0.5 1.0 0.0 0.2 0.2 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.7 1.7 0.3 2.2 0.8 0.1 1.3 0.6 0.8 0.9 0.7 1.6 1.8 1.8 0.5 0.6 0.4 0.0 0.1 0.8 4.1 3.6 0.4 5.7 4.6 1.8 1.0 1.9 1.6 1.0 1.9 2.4 2.3 9.6 4.8 0.0 0.6 0.0 0.0 0.0 0.0 0.0 2.1 1.5 0.0 0.0 1.8 1.8 0.0 0.5 0.4 0.0 19.6 1.1 0.0 3.4 1.8 0.7 0.0 0.0 0.0 2.2 0.1 1.8 0.0 3.2 2.5 3.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 6.8 1.5 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.3 0.4 3.7 0.0 0.0 PRPF18 hPrp18 ENSG00000165630 "Pre-mRNA processing factor 18" Q99633 10 13586939-13630859 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 105.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA037599, HPA047950" Supported Approved "Nuclear speckles,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" Cytosol "HPA037599: AB_10795137, HPA047950: AB_2680221" "unprognostic (5.82e-2)" "unprognostic (7.86e-3)" "unprognostic (4.07e-2)" "unprognostic (1.20e-2)" "unprognostic (3.00e-2)" "unprognostic (6.36e-2)" "prognostic unfavorable (1.06e-4)" "unprognostic (6.12e-2)" "unprognostic (1.74e-1)" "unprognostic (3.06e-2)" "unprognostic (1.94e-1)" "unprognostic (1.56e-1)" "unprognostic (5.93e-3)" "unprognostic (2.82e-2)" "unprognostic (2.20e-1)" "unprognostic (8.09e-2)" "unprognostic (1.63e-1)" 14.6 15.9 8.4 14.4 9.7 43.0 19.6 12.2 10.4 12.8 8.9 16.0 16.9 14.0 28.1 15.8 11.7 15.5 14.3 8.5 10.8 20.7 21.9 14.9 18.2 8.7 8.7 12.9 17.0 18.7 10.7 17.4 8.7 14.3 18.1 10.1 14.3 13.0 23.2 14.3 16.5 15.1 8.6 13.6 15.0 18.8 9.1 25.0 23.6 22.2 19.7 16.4 12.3 10.1 29.5 21.7 18.9 16.4 25.9 24.7 23.5 33.6 16.6 35.9 34.2 20.8 43.8 24.4 18.3 31.1 16.3 23.8 25.1 27.8 41.3 36.3 24.9 28.4 18.5 16.3 30.7 22.6 32.9 19.4 44.3 31.3 15.4 21.9 35.3 35.0 29.9 32.1 33.1 30.5 42.2 15.6 17.8 29.0 10.7 29.8 22.8 30.6 23.9 12.6 13.2 32.7 26.6 18.8 29.1 23.0 29.0 36.6 30.2 22.2 26.1 36.5 25.5 31.2 35.8 34.8 32.8 27.9 15.4 27.2 27.3 36.5 27.7 25.1 24.0 26.9 24.8 23.9 27.4 25.8 26.4 32.6 40.3 39.7 37.4 23.3 33.5 16.8 8.4 9.7 12.2 10.4 8.5 10.8 8.7 8.7 8.7 8.6 9.1 10.1 24.5 19.2 22.4 14.7 32.8 45.6 24.0 35.7 25.0 13.5 22.6 15.0 9.4 30.0 32.9 22.0 10.4 30.5 28.7 21.1 41.1 30.9 29.8 27.5 22.8 21.1 12.6 25.9 27.0 29.1 40.4 18.9 19.4 22.0 27.1 10.5 16.4 28.4 26.0 21.9 25.3 21.8 46.8 20.7 18.0 16.5 17.7 19.4 24.9 18.7 29.7 20.2 36.0 28.1 29.3 33.7 28.9 13.2 27.1 16.2 30.2 50.6 31.8 21.7 19.7 20.8 18.3 105.8 41.1 17.1 46.9 41.7 33.2 11.6 19.0 25.8 PRPF19 "hPSO4, NMP200, PRP19, PSO4, SNEV, UBOX4" ENSG00000110107 "Pre-mRNA processing factor 19" Q9UMS4 11 60890547-60906585 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, mRNA processing, mRNA splicing, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012448, HPA038051, HPA059070" Supported Enhanced "Nuclear speckles" NA NA 71000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear speckles" "CAB012448: AB_2170868, HPA038051: AB_2675807, HPA059070: AB_2683896" "unprognostic (5.73e-2)" "unprognostic (2.11e-1)" "unprognostic (2.49e-1)" "unprognostic (2.68e-1)" "unprognostic (4.51e-2)" "unprognostic (1.18e-2)" "prognostic unfavorable (4.11e-8)" "unprognostic (1.03e-1)" "unprognostic (2.13e-1)" "unprognostic (9.37e-3)" "unprognostic (9.53e-2)" "unprognostic (1.54e-1)" "unprognostic (6.70e-2)" "unprognostic (9.62e-2)" "unprognostic (7.12e-2)" "unprognostic (9.04e-2)" "unprognostic (3.41e-3)" 46.1 70.6 89.8 49.8 87.9 67.0 48.8 73.7 100.2 57.4 60.2 54.5 42.9 55.4 34.2 81.7 57.3 29.4 47.9 91.3 94.1 50.4 77.2 34.6 64.1 92.0 80.7 66.6 69.4 79.8 79.3 42.9 92.9 62.1 51.8 46.1 56.5 48.2 75.2 80.3 49.5 47.9 75.6 54.3 54.3 30.5 81.1 78.5 43.4 38.9 73.7 58.7 55.9 84.5 197.5 147.0 161.8 116.2 92.7 80.8 155.6 102.4 137.5 200.2 149.0 162.7 141.1 280.5 145.2 98.2 120.2 179.0 229.2 184.6 153.4 207.0 153.4 232.4 111.3 184.9 134.2 308.6 161.1 86.3 137.0 154.4 171.9 58.7 158.7 167.4 248.2 155.3 99.5 270.6 328.9 249.5 292.6 150.5 197.7 285.8 165.5 227.5 101.7 127.5 142.3 172.9 126.6 208.3 178.0 73.1 225.8 170.2 101.9 89.6 147.2 161.8 171.2 147.2 223.3 287.9 111.6 208.6 138.6 4.2 7.8 2.0 2.4 3.8 1.7 0.9 1.8 1.7 3.6 2.4 2.2 2.0 0.5 1.8 2.3 3.9 1.7 1.0 89.8 87.9 73.7 100.2 91.3 94.1 92.0 80.7 92.9 75.6 81.1 84.5 15.8 19.2 23.7 10.1 26.7 42.1 35.2 40.2 33.0 32.0 24.6 19.4 17.6 20.0 28.6 27.6 10.4 94.7 16.2 20.4 27.4 48.5 21.6 21.4 19.7 27.3 39.0 45.2 19.8 51.6 90.2 24.9 23.4 28.4 22.8 25.4 20.0 46.1 46.3 62.2 22.2 40.0 32.6 23.0 21.6 3.6 37.0 19.3 26.6 11.2 41.2 25.4 21.6 10.1 11.8 33.4 27.7 38.7 31.9 40.4 27.8 27.9 17.8 25.3 46.0 22.4 22.6 25.2 38.0 37.4 41.6 40.6 24.8 24.8 55.1 26.3 PRPF4 "HPRP4, HPRP4P, PRP4, Prp4p, SNRNP60" ENSG00000136875 "Pre-mRNA processing factor 4" O43172 9 113275642-113294009 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021794, HPA022248" Enhanced Enhanced "Nuclear speckles" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nuclear speckles" "HPA021794: AB_1855772, HPA022248: AB_1855773" "unprognostic (1.70e-2)" "unprognostic (6.51e-2)" "unprognostic (3.60e-2)" "unprognostic (1.36e-1)" "unprognostic (1.69e-1)" "unprognostic (3.70e-3)" "prognostic unfavorable (9.35e-4)" "unprognostic (1.95e-2)" "unprognostic (6.57e-2)" "unprognostic (3.14e-2)" "unprognostic (5.00e-2)" "unprognostic (6.76e-3)" "unprognostic (2.18e-3)" "unprognostic (4.43e-2)" "unprognostic (1.29e-1)" "unprognostic (1.42e-1)" "unprognostic (1.57e-2)" 11.6 14.7 9.2 15.2 9.5 15.1 13.4 10.3 10.9 11.2 8.6 11.1 9.9 13.5 19.4 14.9 12.3 10.3 11.0 9.4 9.5 15.4 16.2 9.4 15.6 8.9 8.9 14.8 14.4 25.4 12.2 12.5 9.2 13.3 12.3 13.1 11.2 11.1 18.1 14.6 9.8 13.2 9.0 11.6 10.3 11.6 9.1 16.9 10.2 15.2 17.6 16.7 11.3 9.6 36.6 61.3 40.3 44.4 27.8 28.6 40.4 56.1 28.1 60.2 44.2 60.4 33.4 76.5 32.5 30.3 62.2 81.8 84.9 48.8 66.2 54.2 32.1 39.1 50.4 43.7 25.2 68.0 34.2 20.7 32.7 63.1 59.9 22.6 28.9 41.8 67.5 40.9 51.2 57.3 65.1 47.9 63.9 94.2 66.5 59.4 95.9 51.4 26.0 28.9 52.7 35.5 82.9 44.0 26.0 32.0 68.3 35.0 29.8 49.1 37.3 63.0 72.4 52.1 153.1 73.3 37.6 42.9 63.8 27.4 16.2 16.1 14.7 19.4 17.1 17.1 14.4 13.3 20.4 17.4 14.5 14.6 5.2 18.4 24.6 13.4 14.6 14.8 9.2 9.5 10.3 10.9 9.4 9.5 8.9 8.9 9.2 9.0 9.1 9.6 15.7 9.6 18.4 6.8 23.7 15.7 17.6 10.4 18.8 22.9 12.7 14.6 12.9 12.8 15.2 18.4 18.8 27.7 26.6 5.8 25.4 18.6 17.2 17.5 24.7 12.6 17.5 20.0 8.6 16.9 34.5 16.4 10.2 21.9 19.0 21.5 6.4 9.9 18.4 28.6 8.3 13.0 10.2 13.5 17.8 13.0 11.5 20.5 5.4 2.8 27.3 22.7 18.6 4.0 5.7 15.5 9.6 10.9 15.7 20.6 8.1 16.9 14.3 24.1 0.0 16.9 17.5 28.6 21.0 21.4 18.8 21.5 20.0 24.7 14.0 16.9 PRPF40A "FBP-11, FBP11, FLAF1, FLJ20585, FNBP3, HIP10, HYPA, NY-REN-6, Prp40" ENSG00000196504 "Pre-mRNA processing factor 40 homolog A" O75400 2 152651593-152717997 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038272, HPA038273" Approved Enhanced "Nuclear speckles" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 39: CACO-2 - Unknown function" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "HPA038272: AB_2675923, HPA038273: AB_10671526" "unprognostic (1.81e-1)" "unprognostic (2.91e-1)" "unprognostic (4.31e-3)" "unprognostic (4.49e-3)" "unprognostic (1.55e-3)" "unprognostic (1.35e-1)" "prognostic unfavorable (1.68e-4)" "unprognostic (4.62e-2)" "unprognostic (3.61e-3)" "unprognostic (1.23e-2)" "prognostic unfavorable (1.58e-5)" "unprognostic (1.03e-1)" "prognostic unfavorable (5.89e-4)" "unprognostic (1.80e-2)" "unprognostic (2.32e-1)" "unprognostic (3.24e-2)" "unprognostic (2.05e-2)" 16.7 16.7 9.0 24.7 9.8 45.0 21.5 14.3 10.4 16.8 9.4 24.2 23.0 18.6 15.7 27.6 18.0 17.4 15.3 8.7 10.3 18.9 21.7 17.4 30.4 10.4 8.7 18.9 19.7 24.0 10.5 22.2 10.9 18.4 20.9 16.7 16.6 15.0 22.8 21.0 23.0 17.4 9.9 20.7 22.2 25.5 8.7 31.5 24.6 20.0 28.1 27.1 15.1 12.3 63.4 62.9 68.9 70.8 39.1 51.8 95.5 61.8 55.2 86.0 78.9 120.0 57.8 130.9 88.0 62.7 49.2 63.8 90.8 74.3 91.6 72.4 78.6 121.8 55.7 79.9 50.7 135.4 81.6 41.7 61.9 113.8 127.3 52.4 67.5 60.8 133.2 60.6 52.9 38.4 57.2 63.4 102.9 41.2 75.8 110.4 73.3 86.9 43.7 99.8 82.2 56.0 73.9 53.5 67.6 50.6 46.8 85.4 79.1 90.3 56.6 51.9 81.4 38.8 67.7 130.6 57.9 78.2 56.1 87.6 70.1 91.7 66.7 86.5 62.3 65.5 62.1 60.7 79.4 70.3 65.5 58.8 61.1 70.4 101.1 84.8 58.8 80.1 9.0 9.8 14.3 10.4 8.7 10.3 10.4 8.7 10.9 9.9 8.7 12.3 98.5 112.2 118.5 48.3 120.3 141.0 120.0 117.9 101.3 65.0 73.6 70.6 64.4 55.8 122.1 53.3 73.0 123.1 123.7 67.2 49.0 110.0 150.3 101.0 126.6 97.4 78.3 105.6 56.4 111.5 155.9 96.4 74.9 121.0 123.4 111.0 53.9 72.5 109.2 60.6 53.3 81.5 87.5 95.7 114.5 36.4 69.3 125.5 55.2 44.0 184.1 62.7 107.1 44.7 71.3 128.3 86.8 79.7 112.1 131.7 69.5 75.7 152.6 75.2 98.6 104.8 132.1 239.0 121.4 141.6 151.7 132.2 119.9 164.9 103.7 148.4 PRPF4B "KIAA0536, PR4H, Prp4" ENSG00000112739 "Pre-mRNA processing factor 4B" Q13523 6 4021267-4064983 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020638 Approved Supported "Nuclear speckles" NA NA "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "HPA020638: AB_1855774" "unprognostic (1.03e-1)" "unprognostic (2.66e-1)" "unprognostic (4.95e-2)" "unprognostic (2.20e-1)" "unprognostic (3.59e-3)" "unprognostic (1.21e-2)" "prognostic unfavorable (2.27e-4)" "unprognostic (8.68e-3)" "unprognostic (3.41e-2)" "unprognostic (4.45e-3)" "unprognostic (2.17e-1)" "unprognostic (1.07e-1)" "unprognostic (9.50e-3)" "unprognostic (8.90e-2)" "unprognostic (2.34e-1)" "unprognostic (7.63e-3)" "prognostic favorable (6.82e-5)" 9.1 7.2 4.8 11.3 5.4 27.3 8.1 7.5 6.7 5.8 5.2 8.6 10.2 9.9 10.1 8.4 4.4 6.1 5.0 4.7 5.1 4.2 4.3 6.8 14.2 5.4 5.5 8.4 6.8 4.2 3.3 7.6 5.3 6.3 8.6 15.9 8.4 5.5 16.3 13.3 9.0 5.6 4.9 11.2 8.1 3.8 5.5 8.8 6.5 4.5 10.0 6.7 7.0 6.9 6.0 3.9 14.4 12.1 8.3 7.3 12.3 7.7 3.4 4.7 5.2 6.9 7.1 8.1 5.7 5.1 4.8 12.8 10.1 6.8 7.1 4.4 11.1 6.7 19.1 11.5 3.6 11.2 10.6 5.7 6.9 5.4 6.6 11.0 5.1 6.5 11.6 3.1 7.4 2.7 7.2 26.3 6.0 3.8 4.3 9.9 6.1 11.2 8.4 10.2 7.9 7.3 4.7 3.9 5.5 16.9 9.6 7.9 7.3 11.2 6.5 4.3 8.2 7.5 7.9 6.9 3.2 7.6 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 5.4 7.5 6.7 4.7 5.1 5.4 5.5 5.3 4.9 5.5 6.9 122.4 109.0 103.2 35.6 110.5 83.5 64.0 43.1 69.4 88.6 80.4 49.5 79.1 61.5 75.1 97.5 89.6 61.8 151.3 94.9 72.4 64.4 15.6 115.9 143.5 85.8 75.3 79.1 42.8 56.8 49.9 78.7 88.2 113.4 90.5 96.2 61.1 85.8 41.1 106.0 49.8 88.8 50.8 71.6 49.4 20.6 98.8 71.4 35.6 49.6 97.4 81.2 118.4 50.8 68.1 62.8 61.5 89.1 101.9 62.8 55.5 89.5 71.7 184.0 59.2 105.3 85.8 66.1 76.5 66.7 91.4 63.6 106.2 93.1 87.7 65.2 PRPF6 "ANT-1, bB152O15.1, C20orf14, hPrp6, Prp6, RP60, SNRNP102, TOM, U5-102K" ENSG00000101161 "Pre-mRNA processing factor 6" O94906 20 63981132-64033100 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047106 Supported Supported "Nuclear speckles" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 39: CACO-2 - Unknown function" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "HPA047106: AB_10963084" "unprognostic (1.29e-1)" "unprognostic (9.96e-3)" "unprognostic (7.02e-2)" "unprognostic (9.36e-3)" "unprognostic (1.80e-1)" "unprognostic (2.34e-1)" "unprognostic (1.66e-3)" "unprognostic (3.37e-2)" "unprognostic (1.44e-2)" "unprognostic (1.14e-1)" "unprognostic (5.76e-3)" "unprognostic (2.18e-1)" "unprognostic (3.16e-3)" "unprognostic (6.16e-2)" "unprognostic (8.04e-2)" "unprognostic (7.19e-2)" "unprognostic (5.39e-3)" 44.0 32.2 33.6 30.8 37.4 33.3 40.1 44.9 37.1 38.5 34.5 39.9 30.0 43.5 27.9 38.9 49.3 27.2 39.0 32.9 34.7 35.3 29.8 32.1 40.9 37.7 35.5 50.6 44.2 37.2 36.7 30.9 37.1 34.5 25.9 36.4 38.3 36.4 64.6 58.3 38.1 29.7 34.6 40.9 37.3 41.0 35.5 44.4 36.2 37.1 40.5 40.5 36.2 46.8 72.8 86.5 62.3 66.3 69.5 48.6 81.5 56.1 62.8 167.9 74.6 233.6 86.2 90.9 133.4 74.5 107.1 110.0 101.2 116.1 88.7 44.0 59.0 76.8 112.7 213.3 76.7 105.3 102.3 55.2 81.4 77.5 89.2 59.9 63.3 83.7 76.2 76.6 56.8 89.2 106.8 131.0 55.4 114.4 106.7 116.0 53.0 87.3 64.4 71.9 61.8 72.4 108.6 110.0 74.1 43.2 108.0 135.5 90.1 96.2 55.1 77.4 104.6 63.7 66.5 94.6 70.3 62.5 76.3 90.8 59.7 73.7 67.0 62.7 93.3 67.1 82.3 72.5 58.6 58.4 95.8 80.9 50.3 130.5 77.8 54.5 79.7 92.3 33.6 37.4 44.9 37.1 32.9 34.7 37.7 35.5 37.1 34.6 35.5 46.8 60.7 60.9 62.6 19.2 69.3 38.4 45.3 50.7 63.2 81.6 54.2 59.8 70.5 34.3 71.6 62.5 37.5 72.5 53.2 43.8 82.2 59.3 49.1 70.3 66.8 55.7 52.7 43.5 12.5 56.7 47.6 51.2 38.7 62.0 91.2 49.0 63.9 55.2 46.3 42.1 14.8 60.6 57.0 44.8 34.1 28.7 58.1 49.9 48.0 5.6 79.7 86.5 57.7 12.5 17.8 65.9 43.9 52.6 67.8 33.5 58.0 65.8 87.7 112.7 59.2 68.2 61.9 120.6 118.9 59.8 46.3 94.5 60.0 32.6 47.7 34.3 PRPS2 ENSG00000101911 "Phosphoribosyl pyrophosphate synthetase 2" P11908 X 12791355-12824222 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Nucleotide biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 147.8;parathyroid gland: 182.0" "Group enriched" "Detected in many" 7 "Leydig cells: 1431.5;Peritubular cells: 1995.0;Sertoli cells: 624.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051269, HPA067599, CAB070417" Enhanced Approved "Nuclear speckles,Vesicles" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 52: Non-specific - Transcription" Vesicles "Nuclear speckles" "CAB070417: AB_11152035, HPA051269: , HPA067599: AB_2685869" "unprognostic (7.50e-2)" "prognostic favorable (1.90e-4)" "unprognostic (2.09e-3)" "unprognostic (1.03e-1)" "unprognostic (1.16e-2)" "unprognostic (1.10e-1)" "unprognostic (7.63e-2)" "unprognostic (4.75e-2)" "unprognostic (6.98e-2)" "unprognostic (2.64e-3)" "unprognostic (4.44e-3)" "unprognostic (1.81e-1)" "unprognostic (7.83e-2)" "unprognostic (2.20e-1)" "unprognostic (1.50e-1)" "unprognostic (1.35e-1)" "unprognostic (2.04e-1)" 11.0 46.0 6.3 24.5 7.3 24.2 19.7 1.9 12.0 54.5 2.5 30.3 14.0 32.8 26.5 16.1 29.7 28.1 5.4 6.9 2.9 28.0 26.1 13.1 36.8 3.0 6.5 147.8 62.8 182.0 3.4 6.1 2.2 21.9 31.3 1.3 27.9 84.0 2.1 21.9 15.8 24.3 4.4 15.6 32.5 131.1 8.8 44.6 18.1 4.2 31.5 22.5 21.2 6.4 114.2 63.7 22.1 40.3 26.7 31.8 14.6 54.4 26.8 53.1 51.1 46.3 78.7 34.9 24.2 23.5 45.3 79.9 43.1 53.7 61.5 89.7 108.0 41.7 49.6 43.3 24.7 77.3 38.9 30.5 35.0 39.1 51.7 26.9 22.1 86.8 30.4 39.8 45.2 68.5 117.6 34.7 49.9 81.0 107.3 61.5 102.7 79.5 33.0 81.7 46.1 33.6 64.9 2.1 38.9 30.2 58.8 32.4 24.9 41.8 32.0 162.5 55.5 103.6 41.3 76.8 44.4 39.4 67.4 25.9 20.1 9.4 17.2 19.4 19.9 27.8 25.0 16.4 28.2 30.6 31.7 23.0 8.0 24.3 12.3 19.9 22.6 28.2 6.3 7.3 1.9 12.0 6.9 2.9 3.0 6.5 2.2 4.4 8.8 6.4 12.2 3.2 8.7 0.7 25.4 64.0 48.5 16.2 41.5 0.6 53.1 15.9 2.0 11.5 12.4 55.2 0.0 1.1 18.5 21.1 72.4 19.3 12.1 24.7 62.5 14.5 21.8 28.4 14.8 39.2 7.3 25.8 31.1 26.4 27.9 16.2 10.4 13.7 24.4 0.0 6.3 27.9 8.2 21.4 44.3 65.8 1431.5 20.7 40.9 3.7 18.2 1.2 18.6 3.5 5.1 24.6 17.4 1995.0 30.7 52.2 6.0 10.4 20.3 0.2 624.5 9.4 19.2 10.3 8.1 29.2 43.8 0.4 27.2 179.2 50.2 36.9 PRR32 CXorf64 ENSG00000183631 "Proline rich 32" B1ATL7 X 126819729-126821786 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "tongue: 22.4" "Cell type enriched" "Detected in single" 13 "Cardiomyocytes: 1.3" "Cancer enriched" "Detected in single" 5 "glioma: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "basal ganglia: 3.5;hippocampal formation: 10.7;pons and medulla: 13.5;thalamus: 8.2" "Not detected" "Not detected" HPA048386 Uncertain Approved "Nuclear speckles,Plasma membrane,Centrosome" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" "Nuclear speckles, Centrosome" "HPA048386: AB_2680380" "unprognostic (7.10e-3)" "unprognostic (7.97e-2)" "unprognostic (3.79e-1)" "unprognostic (2.98e-2)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.5 0.0 4.1 0.1 0.1 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 22.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRR36 ENSG00000183248 "Proline rich 36" Q9H6K5 19 7868719-7874390 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 21.0;pituitary gland: 29.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 13.4;Breast glandular cells: 9.2;Cone photoreceptor cells: 12.5;Horizontal cells: 10.1" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 21.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "REH: 28.7;SCLC-21H: 8.0;SH-SY5Y: 17.9;T-47d: 9.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062741 Uncertain Approved "Nucleoplasm,Nuclear speckles,Golgi apparatus" Yes No "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 14: REH - Unknown function" "Cluster 35: Glandular cells - Unknown function" "Golgi apparatus" "Nucleoplasm, Nuclear speckles" "HPA062741: AB_2684860" "unprognostic (3.15e-2)" "unprognostic (1.02e-1)" "unprognostic (6.23e-2)" "unprognostic (5.61e-2)" "unprognostic (1.72e-1)" "unprognostic (1.20e-2)" "unprognostic (9.62e-2)" "unprognostic (3.46e-3)" "unprognostic (1.18e-1)" "unprognostic (1.15e-3)" "unprognostic (1.75e-2)" "unprognostic (2.99e-1)" "unprognostic (5.69e-3)" "unprognostic (7.89e-2)" "prognostic favorable (7.74e-4)" "unprognostic (3.56e-1)" "unprognostic (8.52e-3)" 0.1 0.9 3.5 0.1 4.0 0.0 2.5 3.0 21.0 0.8 0.0 0.3 0.2 0.6 0.3 0.3 1.2 0.1 0.2 7.5 0.0 3.3 0.2 0.9 0.0 0.0 0.0 0.7 2.8 2.0 29.6 0.0 0.0 2.5 0.0 5.0 4.1 0.3 0.0 0.7 0.2 0.0 0.0 0.1 0.8 0.8 0.0 0.0 1.1 0.0 0.0 0.3 0.3 0.0 0.1 0.9 6.6 5.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.4 2.9 0.0 1.9 0.0 0.6 0.1 5.1 0.0 0.0 0.0 6.4 0.0 0.3 1.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 3.2 0.1 0.1 0.0 3.0 0.3 0.3 2.5 0.4 0.6 28.7 0.0 0.3 3.7 5.4 8.0 17.9 0.0 0.3 0.0 0.5 9.1 0.0 0.0 0.0 3.2 0.1 0.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 4.0 3.0 21.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.0 0.5 0.0 0.8 0.0 2.2 13.4 9.2 7.7 1.3 2.8 0.0 5.5 12.5 0.2 0.2 0.2 5.9 3.0 5.4 4.5 0.7 0.2 3.6 0.0 6.9 0.9 0.4 0.3 2.6 6.7 0.0 1.1 0.0 0.5 0.1 10.1 5.8 0.7 0.0 0.0 0.0 0.7 0.6 0.4 0.0 3.7 0.0 5.4 0.0 4.5 0.8 0.9 0.1 0.0 0.6 1.3 0.1 1.5 0.0 4.5 0.0 0.3 1.1 0.3 3.7 3.1 0.0 0.3 0.3 0.5 0.3 1.0 PSKH1 ENSG00000159792 "Protein serine kinase H1" P11801 16 67893254-67929676 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053927, HPA062763" Approved Supported "Nuclear speckles,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 40: Granulosa cells - Unknown function" "Nuclear speckles, Cytosol" "HPA053927: AB_2682312, HPA062763: " "unprognostic (2.57e-2)" "unprognostic (8.91e-3)" "unprognostic (1.88e-1)" "unprognostic (5.79e-2)" "unprognostic (3.26e-1)" "unprognostic (3.89e-1)" "unprognostic (1.64e-1)" "unprognostic (1.29e-2)" "unprognostic (3.03e-1)" "unprognostic (1.66e-2)" "unprognostic (9.85e-3)" "unprognostic (8.32e-2)" "prognostic favorable (4.28e-10)" "unprognostic (1.46e-1)" "unprognostic (1.99e-1)" "unprognostic (4.15e-2)" "unprognostic (3.90e-3)" 14.3 18.6 12.8 9.6 14.5 5.2 14.0 12.2 13.5 13.5 19.5 18.2 13.7 19.3 10.0 16.9 18.7 10.1 17.6 11.2 11.5 20.5 16.5 12.7 10.6 15.0 14.9 19.4 26.3 32.9 13.2 7.6 13.4 15.1 10.8 4.0 18.1 12.7 15.3 13.8 15.7 15.7 13.2 12.8 21.4 21.8 13.6 12.0 15.0 13.5 8.5 16.5 9.5 14.9 13.0 22.7 25.2 28.1 38.4 19.3 16.3 15.2 23.0 15.8 14.0 17.2 18.2 12.2 22.7 25.7 12.7 19.2 14.7 15.6 5.3 4.8 16.4 13.9 16.8 22.0 26.3 13.4 8.0 35.7 26.7 18.8 19.6 21.3 23.3 22.5 21.6 5.1 16.7 28.7 18.3 8.6 24.2 14.0 13.9 27.7 9.7 25.3 18.6 16.0 21.8 26.0 47.3 12.8 15.8 9.9 23.5 23.9 20.8 17.7 6.2 15.0 7.7 15.3 8.7 26.2 21.4 8.8 19.9 0.0 2.0 1.9 2.0 2.2 1.4 1.5 1.5 2.0 2.1 1.2 1.2 1.7 1.0 2.1 1.5 1.5 0.8 1.7 12.8 14.5 12.2 13.5 11.2 11.5 15.0 14.9 13.4 13.2 13.6 14.9 5.5 0.0 3.6 4.6 2.9 1.1 3.1 5.2 2.2 11.1 5.3 4.6 2.3 7.2 3.8 5.5 6.2 6.2 3.0 11.5 11.7 6.0 14.4 5.8 6.5 5.2 10.8 3.0 4.6 7.4 4.8 5.4 5.1 4.8 6.3 13.0 5.3 10.3 4.8 6.7 6.1 6.2 10.2 6.3 1.6 22.1 4.7 2.9 5.4 3.7 4.8 11.0 3.1 5.5 9.2 7.6 4.5 7.9 3.0 3.6 10.0 8.1 4.9 6.9 13.1 6.3 6.1 6.7 6.1 5.4 1.6 5.9 3.8 10.7 7.4 2.2 PSMD13 "p40.5, Rpn9" ENSG00000185627 "Proteasome 26S subunit, non-ATPase 13" Q9UNM6 11 236966-252984 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038691, HPA038692" Approved Approved "Nuclear speckles,Cytosol" NA NA 81000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 52: Non-specific - Ribosome" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "Nuclear speckles" Cytosol "HPA038691: AB_2676153, HPA038692: AB_10671749" "unprognostic (1.32e-2)" "unprognostic (7.98e-2)" "unprognostic (9.19e-2)" "prognostic favorable (5.74e-4)" "unprognostic (2.24e-2)" "unprognostic (3.13e-2)" "prognostic unfavorable (4.76e-5)" "unprognostic (7.54e-3)" "unprognostic (2.94e-1)" "unprognostic (1.90e-1)" "unprognostic (1.98e-2)" "unprognostic (2.65e-1)" "prognostic unfavorable (1.52e-13)" "unprognostic (1.03e-1)" "unprognostic (2.61e-1)" "unprognostic (1.73e-1)" "unprognostic (2.11e-1)" 56.6 41.3 48.2 65.2 49.1 69.4 74.9 50.0 51.5 57.8 49.5 64.1 57.0 50.7 62.6 63.6 51.8 42.9 76.1 50.3 52.6 53.6 71.8 56.2 79.5 50.3 50.2 40.0 48.9 45.6 18.0 64.9 54.0 67.1 66.7 30.8 46.3 52.0 122.4 62.4 55.7 68.1 51.1 54.3 45.9 44.2 49.5 91.6 48.3 124.3 86.9 65.5 20.1 52.3 240.7 163.7 155.2 163.7 135.3 114.0 102.3 151.8 186.1 277.7 210.6 156.1 352.4 193.0 178.2 172.7 145.5 179.4 154.6 200.2 251.0 202.7 148.7 109.9 52.4 131.7 160.9 203.8 207.7 116.3 149.7 138.4 121.2 114.0 241.7 186.3 249.1 158.1 189.9 126.3 197.4 185.0 243.1 195.0 184.0 168.6 145.3 156.3 190.2 59.2 141.7 111.5 106.5 166.7 111.0 103.6 97.7 123.7 192.6 115.2 96.8 60.3 160.6 161.2 192.4 271.8 185.2 193.0 176.3 198.6 171.3 133.6 145.8 173.0 143.0 125.0 133.1 141.1 176.1 128.6 121.3 130.3 127.8 168.7 194.7 122.1 169.2 286.0 48.2 49.1 50.0 51.5 50.3 52.6 50.3 50.2 54.0 51.1 49.5 52.3 80.8 48.1 41.4 17.0 64.7 35.8 54.1 124.8 26.2 43.2 43.8 41.7 45.7 52.9 68.8 31.3 31.3 162.3 79.9 76.5 82.2 114.8 39.2 41.6 47.1 75.1 48.0 35.7 16.8 130.8 138.6 55.9 34.1 45.2 67.2 59.9 54.7 59.0 100.5 37.0 15.5 75.2 71.2 47.5 43.5 57.8 68.6 64.4 46.2 11.2 91.9 65.0 71.1 8.5 17.2 123.4 65.5 59.8 73.9 58.7 80.8 76.2 61.3 44.2 85.5 40.8 66.9 94.0 86.4 34.4 38.8 205.8 71.6 73.8 74.2 51.4 PSMD8 "HIP6, HYPF, Nin1p, p31, Rpn12, S14" ENSG00000099341 "Proteasome 26S subunit, non-ATPase 8" P48556 19 38374550-38383824 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 708.9" "Cell type enhanced" "Detected in all" "Late spermatids: 1164.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006702, CAB021101" Supported Approved "Nuclear speckles,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "Nuclear speckles" "CAB021101: AB_10061018, HPA006702: AB_1079710" "unprognostic (9.50e-2)" "unprognostic (7.02e-2)" "unprognostic (1.70e-2)" "prognostic unfavorable (3.84e-4)" "unprognostic (1.59e-1)" "unprognostic (5.54e-3)" "unprognostic (1.94e-3)" "unprognostic (5.03e-2)" "unprognostic (2.85e-2)" "unprognostic (1.73e-2)" "unprognostic (4.61e-1)" "unprognostic (8.79e-2)" "prognostic unfavorable (4.66e-4)" "unprognostic (2.28e-1)" "unprognostic (2.08e-2)" "unprognostic (2.58e-3)" "unprognostic (4.84e-2)" 224.8 130.8 102.3 78.0 109.6 118.8 184.9 104.1 114.8 109.6 97.6 111.8 98.1 115.8 119.4 156.6 104.0 69.2 361.8 114.4 117.5 122.4 143.0 114.9 90.8 109.2 104.3 82.1 117.3 150.2 111.1 101.1 121.9 107.1 98.9 60.6 118.8 84.5 708.9 178.4 106.4 105.2 105.4 99.4 117.6 145.8 112.6 120.3 91.2 361.1 109.9 106.3 111.0 112.6 337.3 522.7 202.2 231.9 322.0 256.9 105.9 238.7 322.9 358.9 372.3 362.0 196.3 234.7 242.8 320.0 220.1 114.1 341.7 296.8 321.6 389.8 225.6 256.1 159.6 226.4 415.1 260.8 217.9 261.2 290.8 309.7 408.8 197.3 286.5 279.9 324.9 255.7 400.6 332.8 247.6 146.1 157.8 492.8 282.7 254.7 324.6 187.4 255.7 275.1 210.8 214.3 247.3 315.7 233.8 187.1 165.3 242.0 212.7 272.1 251.5 289.0 355.8 257.2 322.4 318.0 410.1 264.8 310.1 169.0 239.5 132.6 188.2 265.1 160.0 172.8 162.0 181.0 263.1 173.6 133.0 129.5 89.0 182.7 319.8 183.2 295.2 352.3 102.3 109.6 104.1 114.8 114.4 117.5 109.2 104.3 121.9 105.4 112.6 112.6 137.4 67.3 67.9 8.1 122.9 206.0 224.5 293.5 80.2 102.6 116.3 141.0 263.8 81.5 158.8 80.9 54.2 367.2 128.2 194.6 348.3 276.0 422.3 137.2 158.2 127.0 146.0 129.2 14.7 267.4 327.5 146.8 71.4 122.5 93.8 146.9 81.4 123.1 296.9 77.4 15.4 183.9 219.7 93.1 169.5 1164.7 118.4 126.9 199.3 10.3 224.0 179.8 143.2 8.0 19.8 296.8 181.2 117.8 178.9 255.0 305.7 332.4 128.5 120.4 151.2 106.6 221.1 305.1 135.4 120.3 212.3 570.3 133.0 201.0 182.5 218.7 PUS7L DKFZP434G1415 ENSG00000129317 "Pseudouridine synthase 7 like" Q9H0K6 12 43718992-43758793 "Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056203, HPA058750" Uncertain Approved "Nucleoli,Nuclear speckles" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" Nucleoli "HPA056203: AB_2683064, HPA058750: AB_2683807" "unprognostic (3.41e-3)" "unprognostic (1.03e-1)" "unprognostic (2.51e-3)" "unprognostic (1.83e-1)" "unprognostic (3.05e-2)" "unprognostic (1.79e-1)" "unprognostic (5.87e-4)" "unprognostic (1.11e-1)" "unprognostic (8.11e-3)" "unprognostic (1.37e-2)" "unprognostic (3.49e-1)" "unprognostic (2.54e-2)" "unprognostic (1.80e-3)" "unprognostic (1.32e-1)" "unprognostic (2.56e-1)" "unprognostic (2.50e-2)" "unprognostic (9.27e-2)" 2.7 3.1 3.3 4.9 3.6 3.5 5.4 6.8 5.2 4.1 0.3 3.8 3.8 3.6 3.7 4.8 2.9 3.8 2.7 2.9 2.6 3.1 3.2 2.4 5.7 2.6 2.0 4.7 4.3 4.4 4.1 4.0 2.7 4.0 4.5 11.7 4.0 3.5 1.7 3.7 3.6 3.1 1.1 3.4 3.9 3.0 3.2 5.1 5.7 1.7 5.9 3.4 2.7 3.7 11.2 8.3 7.2 4.1 4.9 17.4 12.8 9.6 8.1 12.6 9.6 29.9 7.9 25.7 11.9 11.9 7.3 9.9 10.5 9.7 21.5 7.9 6.5 18.8 9.2 11.2 6.1 30.3 11.7 7.2 7.1 13.1 13.5 11.6 9.2 14.9 33.3 10.9 29.7 4.5 15.8 7.8 13.3 0.0 8.8 14.7 16.9 15.4 5.6 8.5 12.1 3.9 11.9 12.8 5.1 8.5 15.1 8.4 6.7 12.8 8.4 15.0 15.2 9.6 17.7 25.5 11.8 49.1 4.3 6.4 1.9 2.2 2.1 1.7 2.7 2.1 2.3 2.3 2.1 2.8 2.0 2.9 1.3 2.5 1.6 2.3 1.0 1.5 3.3 3.6 6.8 5.2 2.9 2.6 2.6 2.0 2.7 1.1 3.2 3.7 30.5 9.6 17.2 29.0 41.1 11.6 19.0 30.8 22.8 68.9 24.2 16.0 12.3 14.3 21.2 25.8 68.8 34.3 34.4 13.5 41.1 20.4 2.5 14.9 28.5 23.3 19.3 25.2 49.5 23.2 23.3 26.5 28.5 18.9 17.1 43.7 16.8 20.8 20.4 43.7 79.5 25.2 18.3 25.0 10.5 4.2 20.2 20.3 12.4 15.0 24.6 33.1 35.0 41.7 51.2 18.2 17.0 26.7 48.7 16.9 19.6 22.7 9.2 106.1 19.7 28.1 18.1 25.2 35.3 19.9 11.1 24.2 32.7 36.3 30.0 13.9 PYROXD1 "DKFZp762G094, FLJ22028" ENSG00000121350 "Pyridine nucleotide-disulphide oxidoreductase domain 1" Q8WU10 12 21437615-21471250 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Oxidoreductase "Disease variant, Limb-girdle muscular dystrophy, Myofibrillar myopathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 179.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038319, HPA038320" Uncertain Approved "Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 18: U-2197 - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "Nuclear speckles" "HPA038319: AB_10669522, HPA038320: AB_2675956" "unprognostic (1.48e-1)" "unprognostic (1.68e-1)" "unprognostic (1.15e-2)" "unprognostic (9.89e-2)" "unprognostic (1.51e-1)" "unprognostic (2.64e-3)" "unprognostic (1.50e-1)" "unprognostic (9.31e-2)" "unprognostic (8.94e-3)" "unprognostic (1.17e-2)" "unprognostic (1.57e-1)" "unprognostic (3.32e-2)" "unprognostic (1.06e-2)" "unprognostic (3.78e-2)" "unprognostic (2.30e-2)" "unprognostic (2.00e-1)" "prognostic favorable (1.70e-4)" 7.9 10.0 3.8 9.2 4.3 9.3 10.4 5.1 5.4 7.1 5.3 11.9 13.9 7.1 8.6 8.3 7.1 8.7 10.7 3.7 5.2 16.8 12.3 8.6 10.6 5.4 5.2 6.6 13.4 10.4 5.2 5.9 5.3 9.9 11.2 14.0 11.9 5.9 12.4 10.0 16.0 6.4 4.7 7.9 12.8 5.8 4.2 7.5 15.6 9.6 8.5 7.6 6.1 5.4 9.3 3.5 5.2 5.8 3.7 6.8 11.8 14.5 6.7 5.2 4.0 4.5 8.6 10.2 6.0 11.0 4.4 11.3 5.8 11.4 5.8 12.1 5.1 11.8 9.2 5.7 17.2 17.7 12.0 11.3 13.5 3.3 14.3 6.7 7.8 11.0 5.8 4.2 10.7 5.9 8.3 24.3 8.6 8.2 6.5 1.4 11.2 11.2 16.3 9.2 1.7 13.1 6.7 12.2 27.0 7.1 14.5 20.8 11.2 6.2 5.9 13.5 13.4 6.4 4.8 12.7 25.4 13.1 7.5 1.2 0.8 0.6 1.7 1.5 1.9 1.2 2.0 2.1 0.8 0.9 1.6 1.7 0.3 1.6 2.7 1.1 1.6 0.9 3.8 4.3 5.1 5.4 3.7 5.2 5.4 5.2 5.3 4.7 4.2 5.4 12.5 12.8 28.4 12.7 18.3 6.6 10.2 10.7 8.0 21.8 15.1 10.8 11.7 27.1 13.6 27.6 25.0 15.4 22.9 40.0 23.5 24.7 179.8 26.0 13.0 9.4 20.4 13.3 14.0 33.4 14.2 10.4 19.9 21.1 25.3 8.6 8.9 21.2 16.2 8.4 17.0 21.3 12.2 21.8 5.8 32.6 10.5 18.1 5.4 17.8 15.6 14.5 17.5 13.0 34.2 41.2 25.1 6.4 19.5 12.0 39.4 43.8 28.6 28.2 13.1 15.0 13.8 49.7 18.8 14.5 7.7 19.4 20.1 10.6 20.6 14.1 R3HCC1L "C10orf28, GIDRP86, PSORT" ENSG00000166024 "R3H domain and coiled-coil containing 1 like" Q7Z5L2 10 98134624-98244897 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 51.5;Oligodendrocytes: 59.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037367 Enhanced Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Nuclear speckles" "HPA037367: AB_10696930" "unprognostic (3.00e-1)" "unprognostic (2.55e-2)" "unprognostic (1.72e-2)" "unprognostic (2.39e-1)" "unprognostic (7.67e-2)" "unprognostic (7.04e-2)" "unprognostic (1.15e-3)" "unprognostic (1.33e-1)" "unprognostic (1.73e-1)" "unprognostic (1.40e-1)" "unprognostic (6.00e-2)" "unprognostic (1.55e-1)" "unprognostic (1.74e-3)" "unprognostic (7.39e-2)" "unprognostic (3.12e-1)" "unprognostic (1.49e-1)" "unprognostic (1.43e-2)" 12.8 8.5 8.8 7.8 10.0 17.4 11.6 10.9 11.1 14.2 9.1 12.1 6.4 8.9 9.7 13.1 9.2 5.9 8.3 8.5 8.9 11.8 13.5 10.9 12.2 9.7 9.3 8.7 11.0 10.5 8.6 8.3 9.7 12.7 10.1 10.0 11.8 6.6 9.9 15.1 12.3 6.5 9.4 15.3 9.5 31.1 9.5 13.7 10.1 8.0 13.0 12.4 13.1 10.9 14.6 9.4 13.9 12.4 11.7 12.4 11.5 16.1 22.4 15.4 17.0 12.8 10.0 20.4 8.5 9.6 8.7 16.0 14.2 9.7 17.4 15.4 9.6 12.1 7.3 14.4 14.4 16.7 14.1 11.4 10.9 13.6 20.0 13.6 10.1 12.6 10.6 12.4 12.2 14.0 13.2 17.3 10.1 6.9 12.1 13.4 15.9 8.2 11.2 8.5 4.8 10.2 8.3 6.0 32.9 17.7 10.8 10.4 11.2 10.3 11.0 11.6 12.2 12.5 14.1 34.4 14.8 17.1 7.7 12.2 6.3 17.8 8.6 8.8 7.8 9.2 8.9 8.9 5.0 8.6 7.7 7.7 7.6 10.4 13.4 5.5 13.4 5.5 8.8 10.0 10.9 11.1 8.5 8.9 9.7 9.3 9.7 9.4 9.5 10.9 11.8 16.0 15.1 30.0 13.2 3.3 4.8 3.9 6.8 6.7 5.9 5.0 8.9 10.0 6.5 7.3 6.2 9.8 15.6 13.5 5.9 7.8 28.4 10.8 10.5 9.5 6.0 11.8 39.9 6.9 9.8 8.3 14.3 10.1 17.1 9.7 6.1 4.5 6.9 5.0 35.8 12.2 2.0 8.7 5.1 13.1 5.3 13.5 12.4 51.5 9.5 6.5 13.4 34.2 59.8 10.5 5.4 5.7 11.9 5.4 9.6 3.4 13.0 14.2 0.0 7.6 7.1 36.6 23.9 6.3 3.8 13.0 12.8 8.7 9.5 7.5 RAD52 ENSG00000002016 "RAD52 homolog, DNA repair protein" P43351 12 911736-990053 "Cancer-related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Astrocytes: 34.9;Excitatory neurons: 38.0;Inhibitory neurons: 48.8;Microglial cells: 23.4;Oligodendrocyte precursor cells: 30.2;Oligodendrocytes: 54.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028957 Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear speckles" "Plasma membrane" "HPA028957: AB_2672842" "unprognostic (4.53e-1)" "unprognostic (8.08e-3)" "unprognostic (4.68e-2)" "unprognostic (5.27e-2)" "unprognostic (7.37e-2)" "unprognostic (1.42e-2)" "unprognostic (1.82e-3)" "unprognostic (1.88e-1)" "unprognostic (2.80e-2)" "unprognostic (8.43e-2)" "unprognostic (1.03e-2)" "unprognostic (3.27e-1)" "prognostic unfavorable (2.22e-6)" "unprognostic (1.54e-1)" "unprognostic (1.61e-1)" "unprognostic (1.68e-1)" "unprognostic (3.74e-2)" 4.9 4.7 5.9 5.0 8.2 3.6 6.0 7.8 8.4 8.8 5.1 7.2 5.8 7.3 8.4 4.7 6.6 4.2 4.7 7.1 7.0 7.6 6.4 4.0 6.3 7.2 7.3 10.8 6.6 4.9 5.2 5.4 7.6 6.2 7.0 6.8 4.4 6.0 12.3 9.8 6.6 6.1 5.3 6.0 5.5 4.4 7.8 7.0 8.3 6.8 5.9 6.1 5.8 13.7 4.0 15.2 11.6 13.8 12.1 9.7 12.7 7.9 7.5 9.0 8.7 14.8 14.3 12.8 2.4 8.2 7.4 12.0 9.4 5.4 7.7 17.7 8.2 14.6 16.2 10.0 7.0 15.6 4.2 5.5 9.4 9.1 28.3 17.6 7.4 12.4 9.8 7.5 8.6 8.7 10.8 15.7 15.4 10.0 9.9 10.8 11.6 4.8 9.4 7.1 4.3 5.0 10.3 10.8 6.0 16.8 10.2 7.5 7.4 12.3 14.6 9.8 8.6 2.7 4.6 13.5 6.3 6.9 4.5 7.0 2.1 1.5 2.9 1.9 3.5 2.9 3.0 2.5 2.7 4.0 3.3 3.2 2.0 2.6 2.5 6.0 2.9 1.0 5.9 8.2 7.8 8.4 7.1 7.0 7.2 7.3 7.6 5.3 7.8 13.7 2.5 3.2 5.9 34.9 3.4 1.8 1.4 1.7 4.0 4.2 2.7 2.7 3.6 2.8 3.2 3.7 2.1 4.8 4.5 5.9 1.9 2.3 4.0 2.3 4.5 3.4 1.8 4.2 38.0 1.6 2.8 3.3 5.1 2.6 5.7 4.5 0.7 2.6 2.5 3.3 48.8 2.0 0.0 1.0 2.9 7.5 0.6 2.6 0.0 23.4 2.8 1.4 1.0 30.2 54.5 0.9 3.4 0.7 2.3 1.6 3.9 1.8 1.7 2.6 6.6 4.2 3.9 4.0 4.7 1.9 1.0 2.1 2.6 2.2 3.3 0.8 RADX "CXorf57, FLJ10178, FLJ14191" ENSG00000147231 "RPA1 related single stranded DNA binding protein, X-linked" Q6NSI4 X 106611930-106679439 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.3;pituitary gland: 20.3" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 12.3;Extravillous trophoblasts: 4.7;Syncytiotrophoblasts: 22.6" "Cancer enhanced" "Detected in many" "urothelial cancer: 4.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 10 "B-cells: 1.8;NK-cells: 1.0;T-cells: 1.6" "Cell line enhanced" "Detected in many" "HEK 293: 37.2;RT4: 39.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA000896, HPA001010, HPA001374" Uncertain Supported "Nuclear speckles" NA No "Cluster 40: NK-cells - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nuclear speckles" "HPA000896: AB_1078880, HPA001010: , HPA001374: AB_2666288" "unprognostic (3.30e-2)" "unprognostic (5.59e-3)" "unprognostic (2.67e-2)" "unprognostic (1.46e-3)" "unprognostic (4.85e-2)" "unprognostic (8.26e-2)" "unprognostic (1.24e-2)" "unprognostic (1.89e-1)" "unprognostic (3.02e-1)" "unprognostic (5.49e-2)" "unprognostic (3.81e-3)" "unprognostic (1.17e-1)" "unprognostic (4.20e-3)" "unprognostic (1.63e-1)" "unprognostic (2.70e-1)" "unprognostic (2.21e-2)" "unprognostic (1.23e-3)" 1.0 7.2 6.1 1.4 5.6 0.6 1.4 2.5 4.5 3.7 1.7 1.2 1.1 3.2 2.1 1.0 3.8 0.6 1.1 3.4 27.3 2.5 1.4 2.4 3.3 4.5 4.9 6.7 1.9 0.8 20.3 3.6 6.1 0.8 0.8 1.8 0.8 1.2 1.8 2.5 1.8 0.9 3.6 2.3 2.6 3.9 20.6 2.3 3.0 1.0 2.1 2.5 1.9 5.3 7.2 0.0 7.2 10.1 4.0 3.4 10.8 0.3 1.4 0.0 0.1 1.6 1.5 15.0 0.0 0.8 7.7 2.0 18.6 3.2 0.0 0.0 37.2 5.0 0.0 0.4 0.2 0.0 3.2 2.0 2.2 0.5 1.3 1.9 0.0 13.1 0.2 19.1 1.6 0.0 14.0 0.0 6.5 4.8 1.1 0.0 6.7 0.0 3.1 39.9 11.8 0.0 0.7 0.2 4.3 5.5 1.8 0.2 0.0 3.1 2.6 0.0 4.5 6.8 3.1 18.5 5.5 0.0 5.3 0.0 0.0 0.0 1.5 0.0 1.1 1.8 1.3 1.0 0.0 1.3 1.6 1.3 0.1 1.0 0.0 0.1 0.5 0.4 6.1 5.6 2.5 4.5 3.4 27.3 4.5 4.9 6.1 3.6 20.6 5.3 0.8 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 12.3 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 22.6 1.0 0.0 0.0 0.0 RALGAPB "DKFZp781M2411, KIAA1219, RalGAPbeta" ENSG00000170471 "Ral GTPase activating protein non-catalytic subunit beta" Q86X10 20 38472816-38578859 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051454 Approved Approved "Nuclear speckles" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 44: Endometrium - Transcription" "Nuclear speckles" "HPA051454: AB_2681490" "unprognostic (1.06e-1)" "unprognostic (4.08e-2)" "unprognostic (3.99e-2)" "unprognostic (3.42e-3)" "unprognostic (1.34e-1)" "unprognostic (1.06e-1)" "unprognostic (2.72e-3)" "unprognostic (7.28e-2)" "unprognostic (2.33e-1)" "unprognostic (8.93e-3)" "unprognostic (2.71e-1)" "unprognostic (9.51e-2)" "prognostic favorable (7.25e-4)" "unprognostic (3.03e-1)" "unprognostic (3.95e-1)" "unprognostic (1.63e-1)" "unprognostic (7.99e-2)" 9.6 10.6 7.6 12.1 9.5 12.3 16.1 13.4 10.8 12.1 14.3 11.9 12.1 12.0 12.7 13.9 10.9 10.7 10.5 9.6 9.4 14.4 8.5 11.1 12.2 8.7 8.0 11.6 11.7 24.2 10.5 14.3 8.5 14.4 13.3 18.7 10.8 12.7 12.1 13.7 11.9 12.9 7.6 11.1 12.4 20.8 9.7 17.6 18.1 14.4 14.9 15.3 9.3 9.8 25.3 23.4 23.8 17.5 22.5 25.9 25.3 20.3 23.6 24.8 24.3 42.3 18.6 23.7 18.9 23.7 36.5 29.2 22.6 30.8 34.8 13.6 9.6 36.2 21.0 24.3 21.3 29.6 18.4 18.5 39.1 29.3 32.0 19.7 32.9 20.0 26.8 22.9 24.2 16.5 34.1 12.5 17.5 24.9 30.1 19.4 34.0 15.9 16.5 46.7 25.1 27.6 44.9 59.8 37.4 27.2 34.8 15.0 39.2 49.9 19.9 28.6 20.8 26.6 34.9 21.1 36.1 14.2 22.5 1.2 0.9 2.4 1.2 0.7 1.6 1.3 1.7 1.5 1.4 1.0 1.5 1.2 1.7 2.0 1.3 0.9 0.8 0.6 7.6 9.5 13.4 10.8 9.6 9.4 8.7 8.0 8.5 7.6 9.7 9.8 23.1 22.4 17.1 47.7 18.6 13.9 7.4 12.4 17.1 24.4 19.5 12.3 20.0 10.0 17.7 31.3 27.1 10.4 23.4 26.9 3.9 9.4 11.8 24.3 20.2 17.4 12.6 14.9 63.3 9.3 7.8 15.7 30.5 28.8 16.5 19.4 23.2 12.1 9.7 20.2 66.0 16.1 16.2 17.7 11.6 8.7 16.8 14.7 10.6 49.6 15.1 10.0 16.5 58.3 81.0 15.2 20.4 18.8 16.7 16.1 26.9 9.0 20.9 18.3 13.1 16.8 13.5 31.8 24.0 19.7 18.0 15.2 19.4 15.9 15.8 14.2 RAX2 "ARMD6, CORD11, MGC15631, RAXL1" ENSG00000173976 "Retina and anterior neural fold homeobox 2" Q96IS3 19 3769089-3772228 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Sensory transduction, Transcription, Transcription regulation, Vision" DNA-binding "Age-related macular degeneration, Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 40 "retina: 64.5" "Group enriched" "Detected in some" 9 "Cone photoreceptor cells: 123.0;Rod photoreceptor cells: 217.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA052533 Uncertain Approved "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 46: Photoreceptor cells - Phototransduction" "Nuclear speckles" "Nucleoplasm, Cytosol" "HPA052533: AB_2681862" "unprognostic (5.53e-2)" "unprognostic (1.39e-2)" "unprognostic (4.48e-1)" 0.0 0.0 0.2 0.1 0.4 0.4 0.0 0.6 0.6 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.1 0.3 0.3 0.0 0.0 0.3 1.6 0.0 0.4 0.0 0.0 64.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.4 0.6 0.6 0.4 0.3 0.3 0.3 0.4 0.0 0.4 0.7 0.1 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 14.3 0.0 0.1 0.6 0.0 0.0 0.0 123.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 18.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 217.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 RBBP6 "P2P-R, PACT, SNAMA" ENSG00000122257 "RB binding protein 6, ubiquitin ligase" Q7Z6E9 16 24537693-24572863 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA replication, Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 143.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032866, HPA041725, HPA043544" Approved Enhanced "Nuclear speckles" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "Nuclear speckles" "CAB032866: AB_2177791, HPA041725: AB_2677639, HPA043544: AB_2678543" "unprognostic (1.04e-1)" "unprognostic (5.08e-2)" "unprognostic (3.35e-1)" "unprognostic (3.85e-2)" "unprognostic (1.97e-2)" "unprognostic (2.15e-2)" "unprognostic (1.08e-2)" "unprognostic (6.60e-2)" "unprognostic (2.70e-3)" "unprognostic (1.29e-2)" "unprognostic (1.77e-1)" "unprognostic (2.01e-2)" "unprognostic (1.21e-2)" "unprognostic (1.44e-1)" "unprognostic (1.01e-1)" "unprognostic (1.22e-1)" "unprognostic (2.83e-2)" 27.1 25.0 22.9 21.1 23.8 143.6 25.9 33.1 29.9 27.8 21.7 31.5 15.0 33.6 26.3 23.2 32.4 25.5 23.9 22.8 23.5 24.3 26.8 27.9 29.7 24.2 22.8 38.8 22.2 21.8 28.1 31.7 24.4 26.0 20.4 51.1 21.4 19.9 29.7 34.6 26.0 24.1 23.9 29.4 25.6 45.5 24.4 26.6 27.2 25.7 23.5 25.3 24.7 27.7 35.4 18.4 42.5 44.4 31.9 32.9 45.9 28.1 26.1 25.1 27.3 20.5 28.3 49.6 20.3 24.4 28.7 33.3 46.2 24.8 41.9 26.9 35.7 41.9 57.1 58.6 24.7 57.5 23.7 28.8 33.7 33.2 38.9 28.6 36.9 42.2 54.5 43.8 29.7 36.5 45.5 51.2 48.7 24.0 17.3 62.8 42.5 43.3 24.7 31.7 33.4 28.5 39.7 35.1 52.3 47.0 27.4 49.7 32.3 31.0 22.8 27.0 30.8 37.7 40.9 60.9 25.1 36.5 26.1 7.1 1.2 2.0 2.0 2.0 2.2 2.0 2.1 1.5 0.9 1.7 1.8 2.0 2.5 3.5 1.1 3.7 1.7 0.6 22.9 23.8 33.1 29.9 22.8 23.5 24.2 22.8 24.4 23.9 24.4 27.7 139.1 86.6 115.3 47.3 125.7 100.7 103.5 40.8 223.1 67.1 145.6 160.8 147.0 44.3 56.5 27.6 100.1 46.3 88.9 71.5 25.4 48.8 307.5 109.8 123.7 93.7 82.0 83.1 52.5 47.6 57.6 127.1 121.8 203.1 51.3 127.8 64.2 59.5 38.4 62.2 53.4 76.0 28.5 53.5 70.2 41.9 72.4 101.5 62.2 54.4 54.0 53.1 52.5 61.3 58.7 56.4 32.8 58.6 173.7 99.9 54.5 23.9 52.0 61.4 52.6 247.0 112.9 100.3 45.8 161.0 101.7 101.5 110.2 105.3 69.3 111.9 RBM10 "DXS8237E, GPATC9, GPATCH9, KIAA0122, S1-1, ZRANB5" ENSG00000182872 "RNA binding motif protein 10" P98175 X 47145221-47186813 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034972, HPA057372" Approved Enhanced "Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear speckles" "HPA034972: AB_10602919, HPA057372: AB_2683421" "unprognostic (9.07e-2)" "prognostic favorable (6.71e-4)" "unprognostic (7.83e-2)" "unprognostic (1.61e-2)" "unprognostic (1.86e-1)" "unprognostic (3.04e-2)" "unprognostic (4.47e-3)" "unprognostic (8.11e-2)" "unprognostic (9.86e-3)" "unprognostic (1.76e-1)" "prognostic favorable (2.86e-6)" "unprognostic (1.18e-1)" "unprognostic (6.23e-3)" "unprognostic (3.33e-2)" "unprognostic (1.09e-1)" "unprognostic (4.40e-2)" "unprognostic (1.20e-3)" 23.7 31.1 28.5 19.9 28.8 32.5 23.9 32.6 36.4 33.3 26.6 28.8 18.1 29.5 12.4 34.2 31.5 12.1 30.8 28.5 28.4 30.0 32.2 23.9 25.1 28.2 27.9 40.6 32.2 15.9 38.0 17.3 28.3 33.8 11.3 14.8 23.6 15.6 26.5 27.1 27.8 12.5 26.6 33.9 26.4 12.8 29.3 23.6 33.1 12.4 15.9 28.3 29.9 31.9 50.1 52.5 48.9 58.8 25.7 21.0 57.3 36.8 21.4 37.2 35.8 46.4 39.8 60.1 22.0 25.6 47.5 47.7 64.9 46.1 20.4 61.6 59.0 45.1 65.1 48.8 37.5 46.0 52.1 27.7 22.0 61.2 49.8 26.5 40.4 56.5 38.3 47.0 23.0 74.9 84.8 78.2 81.9 37.1 58.0 74.0 41.0 62.2 27.7 42.9 58.6 44.5 56.0 41.6 35.6 29.3 50.9 45.7 35.8 43.7 54.9 47.8 39.5 48.4 42.9 49.5 38.8 32.8 62.3 13.5 8.1 11.4 12.7 10.7 12.0 11.2 10.2 10.8 9.2 11.1 10.0 9.7 7.5 9.9 15.8 10.7 12.7 9.3 28.5 28.8 32.6 36.4 28.5 28.4 28.2 27.9 28.3 26.6 29.3 31.9 17.4 41.7 36.9 22.5 21.6 11.1 22.4 15.0 22.8 26.7 16.5 16.8 36.6 21.5 28.8 9.2 14.6 34.2 21.3 32.2 11.7 20.5 1.3 23.6 20.1 19.6 35.8 14.9 14.8 17.7 28.5 20.2 31.6 31.5 24.1 29.1 16.8 23.3 19.7 21.9 15.4 31.5 10.2 14.2 10.0 2.7 18.0 15.4 16.0 8.4 19.9 14.7 20.6 15.1 18.1 19.8 20.8 25.6 22.5 18.7 23.1 14.3 28.8 27.0 0.0 21.4 21.8 10.7 8.7 23.4 10.5 46.1 23.8 19.7 34.2 18.1 RBM14 "COAA, DKFZp779J0927, SIP, SYTIP1" ENSG00000239306 "RNA binding motif protein 14" Q96PK6 11 66616626-66629934 "Predicted intracellular proteins" "Immunity, Innate immunity, Transcription, Transcription regulation" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006628 Supported Supported "Nuclear speckles" NA NA 31000 "Cluster 39: Non-specific - mRNA processing" "Cluster 43: Testis - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 39: Non-specific - Basic cellular processes" "Nuclear speckles" "HPA006628: AB_1078546" "unprognostic (6.96e-2)" "unprognostic (4.79e-2)" "unprognostic (4.34e-3)" "unprognostic (4.45e-2)" "unprognostic (2.15e-1)" "unprognostic (9.56e-3)" "prognostic unfavorable (2.02e-7)" "unprognostic (4.21e-2)" "unprognostic (1.54e-3)" "unprognostic (1.08e-2)" "prognostic favorable (1.04e-4)" "unprognostic (9.38e-3)" "unprognostic (8.59e-3)" "unprognostic (1.29e-2)" "unprognostic (3.32e-1)" "unprognostic (1.02e-1)" "unprognostic (1.94e-1)" 26.9 32.0 39.9 25.0 40.2 32.6 24.1 52.6 48.0 37.2 48.5 29.4 15.7 30.8 19.1 33.9 37.6 10.7 33.2 40.1 38.9 50.6 40.4 27.3 28.3 39.4 40.6 45.1 34.1 17.5 34.5 19.6 39.4 36.3 18.2 35.8 25.3 14.6 29.7 28.4 29.1 15.6 37.1 40.4 30.1 44.0 39.6 25.7 28.4 11.6 29.2 30.4 28.6 48.6 83.0 77.9 55.9 43.2 25.3 16.8 97.0 45.0 16.4 40.8 24.0 79.2 60.6 130.9 49.2 21.9 45.0 69.0 63.4 36.5 43.3 63.9 68.7 81.7 67.1 71.2 14.1 71.5 70.0 11.8 13.3 41.9 23.3 24.1 31.0 38.2 98.6 83.9 40.2 70.3 122.4 79.4 107.2 69.0 85.7 125.3 65.4 67.3 34.2 71.5 67.0 61.9 78.0 55.9 33.9 45.9 77.3 63.5 50.5 49.4 97.9 40.5 72.6 49.8 75.2 109.0 41.8 68.9 120.1 19.7 24.3 27.3 27.9 26.1 27.2 21.3 24.1 26.8 33.6 21.8 24.3 28.2 9.0 21.7 27.2 21.3 23.1 34.0 39.9 40.2 52.6 48.0 40.1 38.9 39.4 40.6 39.4 37.1 39.6 48.6 12.6 9.6 17.0 0.0 27.4 38.1 45.7 20.7 15.4 24.8 19.1 16.3 16.3 18.6 17.2 14.7 29.2 56.3 32.7 17.7 17.6 26.5 37.3 18.1 16.5 21.3 21.6 23.1 0.0 18.4 54.4 20.1 9.7 17.5 19.7 20.4 22.5 24.5 29.0 11.8 0.0 20.9 24.4 16.0 30.2 27.0 17.1 20.1 12.4 0.0 25.4 18.1 34.0 0.0 0.0 19.3 21.7 16.1 20.7 26.9 19.0 12.2 23.2 49.4 6.6 15.1 21.5 53.9 40.1 20.9 31.1 69.2 29.0 13.7 25.2 32.6 RBM25 "fSAP94, NET52, RNPC7, S164, Snu71" ENSG00000119707 "RNA binding motif protein 25" P49756 14 73058532-73123899 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003025, HPA070713" Supported Enhanced "Nuclear speckles" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "HPA003025: AB_1079748, HPA070713: AB_2686302" "unprognostic (1.15e-2)" "unprognostic (3.24e-1)" "unprognostic (1.42e-1)" "unprognostic (2.28e-1)" "unprognostic (4.85e-2)" "unprognostic (3.47e-2)" "prognostic unfavorable (1.42e-4)" "unprognostic (4.22e-2)" "unprognostic (3.32e-2)" "unprognostic (1.93e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (8.09e-4)" "prognostic unfavorable (4.26e-4)" "unprognostic (6.98e-2)" "unprognostic (2.58e-1)" "unprognostic (2.75e-1)" "unprognostic (1.73e-1)" 31.4 23.2 14.7 36.0 16.2 72.6 30.7 21.5 20.9 28.7 17.2 28.9 23.4 31.4 22.7 28.9 29.5 21.2 22.2 14.5 19.3 20.8 21.2 30.3 40.0 14.9 13.7 31.1 33.2 22.7 25.3 26.7 16.1 22.5 24.0 41.9 31.4 19.8 41.1 33.3 29.9 23.2 12.5 29.7 27.7 28.5 15.9 36.4 29.3 21.9 33.4 28.1 29.8 20.7 97.8 55.6 86.9 66.6 38.1 44.6 76.5 78.4 54.6 59.5 65.2 74.5 61.2 116.7 40.5 54.0 45.1 72.3 100.9 47.2 101.6 73.8 53.3 98.2 43.2 57.7 24.1 87.5 60.0 32.4 33.3 69.7 56.7 51.1 60.0 42.4 102.7 47.6 65.2 73.3 114.4 51.1 73.8 59.6 60.1 97.4 94.8 57.1 49.0 67.4 58.5 55.8 98.5 64.4 35.0 52.2 92.7 37.9 77.2 87.5 85.5 47.3 79.7 50.2 96.0 141.5 39.1 61.3 61.2 17.4 17.2 16.6 19.9 19.2 18.7 22.3 15.8 16.9 18.2 23.7 16.6 17.6 20.3 27.2 17.5 28.7 19.2 11.7 14.7 16.2 21.5 20.9 14.5 19.3 14.9 13.7 16.1 12.5 15.9 20.7 177.8 230.8 319.9 94.7 226.2 227.4 194.3 109.8 198.6 253.8 136.2 139.2 131.5 77.2 191.8 92.0 268.9 151.8 268.4 137.5 17.6 111.0 71.1 160.4 295.6 170.2 155.2 149.3 115.4 122.6 183.5 185.1 146.8 223.2 247.8 183.3 95.3 98.3 113.1 180.0 99.3 146.3 54.9 110.8 180.8 29.2 157.8 169.9 81.8 71.2 176.9 131.2 155.5 84.9 134.1 132.9 111.0 137.7 233.2 236.5 86.3 32.9 137.0 263.0 72.3 234.2 213.4 213.8 212.9 196.7 236.7 185.4 242.9 161.0 162.5 235.1 RBM26 "ARRS2, C13orf10, FLJ20957, PPP1R132, PRO1777, SE70-2, ZC3H17" ENSG00000139746 "RNA binding motif protein 26" Q5T8P6 13 79311824-79406477 "Plasma proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 251.4;Oligodendrocytes: 253.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040252 Approved Approved "Nuclear speckles" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear speckles" "HPA040252: AB_10672895" "unprognostic (5.55e-2)" "unprognostic (4.55e-1)" "unprognostic (2.65e-1)" "unprognostic (3.09e-2)" "unprognostic (3.03e-1)" "unprognostic (2.57e-1)" "unprognostic (3.05e-3)" "unprognostic (2.18e-1)" "unprognostic (8.80e-2)" "unprognostic (1.81e-1)" "unprognostic (2.30e-2)" "prognostic unfavorable (3.46e-4)" "prognostic unfavorable (5.87e-6)" "unprognostic (8.81e-2)" "unprognostic (1.19e-1)" "unprognostic (2.47e-2)" "prognostic favorable (8.20e-4)" 21.7 26.0 17.1 28.5 21.8 37.2 25.6 32.0 30.1 24.9 13.7 21.0 18.6 28.2 28.1 20.9 24.2 17.5 18.8 19.5 18.3 20.3 21.1 21.5 40.4 14.2 14.4 32.8 27.9 19.2 30.2 24.2 15.0 21.2 21.9 40.9 23.7 18.6 26.0 32.4 28.5 20.3 13.8 33.7 25.0 30.0 16.7 29.9 25.4 19.4 34.2 20.8 21.5 22.2 55.3 29.1 70.1 35.9 30.7 32.2 38.1 37.0 30.9 37.5 38.7 39.1 45.9 82.1 29.5 27.3 24.7 51.4 53.0 36.3 54.2 49.6 56.3 63.4 68.0 35.8 23.9 119.9 48.6 21.9 29.6 38.6 53.3 34.4 39.8 50.5 49.0 26.8 41.9 18.7 73.3 63.3 43.6 49.3 16.9 72.9 57.5 43.8 34.9 31.4 53.2 35.6 31.8 38.2 23.4 42.4 34.4 99.0 38.0 31.8 31.7 25.9 38.0 38.5 36.0 100.0 51.6 66.0 38.6 3.8 1.4 2.8 2.9 2.0 3.0 3.7 2.8 2.7 0.8 5.5 4.2 3.7 2.0 2.3 1.5 2.6 3.3 1.0 17.1 21.8 32.0 30.1 19.5 18.3 14.2 14.4 15.0 13.8 16.7 22.2 50.2 57.7 83.5 148.9 80.9 34.7 35.1 25.0 47.8 63.7 36.5 31.0 42.1 35.8 35.6 25.8 73.0 34.3 72.4 34.8 9.8 25.4 49.2 29.0 59.9 43.3 49.1 41.9 251.4 26.0 31.5 41.6 32.1 36.6 55.8 75.9 60.0 40.3 32.9 57.2 170.8 39.2 32.6 53.7 23.0 27.3 65.0 41.6 16.0 137.7 58.0 37.9 56.7 217.6 253.0 27.0 31.5 47.4 65.8 51.1 28.4 19.6 37.7 72.0 52.6 71.3 43.1 102.3 78.1 47.3 35.5 23.0 54.8 57.7 37.5 33.7 RBM27 "ARRS1, KIAA1311, Psc1, ZC3H20" ENSG00000091009 "RNA binding motif protein 27" Q9P2N5 5 146203605-146289223 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA035944, HPA036422" Approved Approved "Nuclear speckles" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 48: Smooth muscle cells - ECM organization" "Nuclear speckles" "HPA035944: AB_10670672, HPA036422: AB_10669987" "unprognostic (8.18e-2)" "unprognostic (3.17e-1)" "unprognostic (6.04e-2)" "unprognostic (7.03e-2)" "unprognostic (2.75e-2)" "unprognostic (2.04e-3)" "prognostic unfavorable (8.58e-4)" "unprognostic (4.73e-2)" "unprognostic (4.59e-2)" "unprognostic (1.65e-2)" "unprognostic (1.19e-2)" "unprognostic (2.90e-2)" "unprognostic (1.16e-2)" "unprognostic (4.49e-2)" "unprognostic (5.51e-2)" "unprognostic (6.67e-3)" "unprognostic (4.09e-3)" 7.3 5.4 4.1 8.4 4.2 19.5 9.4 7.0 4.9 8.3 4.0 7.8 7.5 9.3 8.0 7.3 7.4 5.9 7.0 3.9 4.8 8.0 10.6 6.7 11.7 3.5 4.5 10.9 6.0 8.9 3.6 9.2 4.0 7.6 8.3 9.4 6.3 6.4 7.2 7.2 7.3 7.6 4.3 9.4 8.6 10.1 4.6 12.6 10.9 9.2 11.3 9.3 5.9 4.9 15.0 12.1 15.3 24.8 13.1 12.5 17.7 10.9 12.3 15.7 17.2 21.3 18.9 31.7 8.4 12.5 21.5 15.3 23.1 25.2 27.7 24.3 10.2 21.7 12.9 14.9 14.4 34.3 24.1 11.7 13.0 16.9 29.9 12.1 14.2 14.9 24.3 18.7 15.0 13.5 25.0 17.4 21.2 16.5 13.6 22.2 23.7 21.9 16.0 16.6 19.1 13.1 22.5 21.7 17.8 15.6 25.3 18.7 13.5 16.6 17.6 12.5 17.8 17.7 18.1 36.6 12.5 24.7 15.7 1.7 0.8 1.6 1.4 1.3 1.6 1.2 1.4 1.6 1.1 1.4 1.8 1.5 1.2 1.8 1.5 1.3 1.5 0.7 4.1 4.2 7.0 4.9 3.9 4.8 3.5 4.5 4.0 4.3 4.6 4.9 12.7 16.0 17.6 20.5 13.1 66.2 9.5 52.6 6.2 11.2 13.0 8.6 17.3 5.7 32.3 14.7 10.4 9.2 17.6 10.1 1.9 7.8 32.4 15.1 11.8 15.7 10.8 11.8 32.2 6.8 8.3 17.0 11.2 13.9 22.1 12.2 11.4 12.1 11.2 15.2 31.4 13.8 30.5 20.4 40.6 6.6 11.5 14.1 19.6 28.1 16.9 8.4 12.3 28.6 43.8 11.5 8.7 14.7 7.3 17.4 9.9 7.9 36.8 8.7 0.0 16.5 24.1 31.4 13.2 12.0 62.1 9.7 15.7 9.8 12.5 19.7 RBM39 "CAPER, CAPERalpha, CC1.3, fSAP59, HCC1, RNPC2" ENSG00000131051 "RNA binding motif protein 39" Q14498 20 35701347-35742312 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001591 Supported Supported "Nucleoplasm,Nuclear speckles,Microtubules,Centriolar satellite" NA NA 19000 "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nuclear speckles" "Microtubules, Centriolar satellite" "HPA001591: AB_1079749" "unprognostic (1.37e-2)" "unprognostic (4.97e-1)" "unprognostic (2.72e-2)" "unprognostic (9.09e-2)" "unprognostic (3.47e-1)" "unprognostic (4.99e-2)" "unprognostic (3.55e-3)" "unprognostic (4.56e-2)" "unprognostic (7.83e-2)" "unprognostic (2.65e-1)" "unprognostic (2.04e-2)" "unprognostic (7.65e-3)" "prognostic unfavorable (2.78e-5)" "unprognostic (1.88e-1)" "unprognostic (2.86e-1)" "unprognostic (2.64e-1)" "unprognostic (2.28e-3)" 70.1 55.8 18.4 37.7 17.6 172.0 44.6 33.5 28.0 57.8 22.2 56.0 35.1 54.5 9.2 62.3 61.4 40.8 57.3 16.5 25.0 52.2 47.7 62.2 42.3 24.2 24.0 71.1 41.2 27.3 50.0 40.9 19.4 50.2 16.9 49.5 53.4 22.3 70.3 51.2 46.9 19.2 16.0 56.4 49.7 34.3 16.9 51.1 54.2 33.1 24.1 50.7 62.1 26.5 98.8 87.6 77.0 78.5 48.8 53.8 78.8 131.0 50.6 59.6 60.2 109.3 78.5 137.5 90.6 38.9 67.9 91.2 122.3 67.9 66.5 94.6 96.7 174.6 80.7 101.2 23.4 158.6 99.9 14.4 97.6 68.9 38.4 63.7 57.8 46.4 195.5 117.6 46.3 72.2 194.5 87.9 103.2 87.5 96.8 104.9 136.2 91.7 41.5 56.2 77.9 63.4 91.1 94.7 78.4 109.3 70.6 94.6 91.4 100.8 92.5 90.5 115.8 71.6 164.3 204.0 64.7 123.2 79.2 250.9 120.4 197.5 104.7 111.1 103.6 131.1 91.5 97.6 111.8 140.5 85.7 82.1 427.7 127.2 102.2 160.9 114.7 95.7 18.4 17.6 33.5 28.0 16.5 25.0 24.2 24.0 19.4 16.0 16.9 26.5 302.0 233.9 280.9 144.3 441.7 616.4 521.0 283.0 284.0 258.5 339.1 295.4 189.2 191.6 267.6 200.5 316.9 375.2 624.9 278.1 189.8 203.8 48.1 359.2 496.0 299.7 295.3 214.2 130.1 186.0 389.6 337.9 254.9 540.8 525.8 304.4 215.3 202.1 199.8 220.4 120.9 331.3 215.7 207.7 469.5 41.9 262.5 335.5 270.3 129.3 274.3 208.7 400.6 136.2 160.5 221.3 254.8 214.4 391.0 453.6 271.8 150.6 248.0 386.5 164.3 504.0 410.2 263.5 228.1 215.8 586.9 561.6 490.8 218.2 282.8 532.1 RBM41 FLJ11016 ENSG00000089682 "RNA binding motif protein 41" Q96IZ5 X 107064420-107118823 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042881 Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" "Nuclear speckles, Cytosol" "HPA042881: AB_10794536" "unprognostic (1.07e-2)" "unprognostic (1.55e-1)" "unprognostic (4.10e-1)" "unprognostic (3.39e-2)" "unprognostic (1.39e-1)" "unprognostic (2.86e-2)" "unprognostic (4.50e-2)" "unprognostic (1.62e-1)" "unprognostic (1.47e-2)" "unprognostic (1.98e-2)" "unprognostic (2.19e-3)" "unprognostic (1.17e-1)" "prognostic unfavorable (3.04e-4)" "unprognostic (1.78e-1)" "unprognostic (1.40e-1)" "unprognostic (2.80e-2)" "unprognostic (1.92e-1)" 4.6 5.8 2.6 5.0 3.0 3.5 5.7 5.7 3.7 4.2 5.1 5.5 7.7 6.1 6.5 5.6 5.0 4.5 5.5 3.0 2.8 6.8 8.3 4.7 5.8 3.9 3.4 5.5 4.2 9.3 3.4 5.4 3.4 5.5 6.5 5.8 4.5 5.0 6.4 7.1 6.9 5.6 3.2 5.3 5.0 7.3 3.2 6.6 6.9 8.0 6.2 5.0 4.1 3.8 16.9 13.3 8.4 6.8 5.5 9.5 9.7 9.8 9.6 7.1 9.5 8.9 13.8 9.3 18.0 7.2 12.4 13.7 12.3 9.2 10.8 11.5 18.1 11.3 25.2 11.0 6.2 11.6 8.5 6.7 17.7 8.6 8.6 9.9 10.8 8.5 19.8 12.5 8.7 8.2 9.9 6.6 12.4 9.3 15.1 7.9 7.0 8.0 10.5 10.5 6.9 10.9 12.2 8.7 7.9 11.4 8.0 5.4 10.6 9.8 5.7 11.7 7.8 5.8 11.6 9.9 5.5 5.2 7.6 10.5 5.2 8.3 4.5 2.7 2.7 5.1 3.9 4.6 3.5 4.3 2.9 1.9 0.7 6.6 2.9 3.6 3.9 2.3 2.6 3.0 5.7 3.7 3.0 2.8 3.9 3.4 3.4 3.2 3.2 3.8 9.6 12.8 17.0 29.0 11.6 5.2 6.6 8.5 12.0 20.3 7.6 6.7 23.2 11.5 8.3 7.3 27.1 8.7 17.4 10.9 1.9 14.8 8.0 27.1 10.1 9.8 7.8 21.0 38.3 7.8 5.3 10.1 8.2 11.6 13.3 19.5 5.3 10.2 6.6 11.8 46.5 8.6 4.1 10.7 4.6 2.3 14.3 12.5 5.4 45.9 11.7 7.4 14.4 50.8 53.4 13.6 11.9 11.7 12.6 5.6 22.0 9.0 13.1 20.2 0.0 14.7 12.4 11.7 8.0 9.0 7.4 4.5 9.7 13.1 11.4 6.2 RBM6 "3G2, DEF-3, DEF3, g16, NY-LU-12" ENSG00000004534 "RNA binding motif protein 6" P78332 3 49940007-50100045 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026272, HPA027164" Enhanced Approved "Nuclear speckles,Cytoplasmic bodies" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 72: Non-specific - Transcription" "Cluster 16: U-266 - Nucleosome" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "Cytoplasmic bodies" "HPA026272: AB_1847592, HPA027164: AB_1847593" "unprognostic (3.81e-3)" "unprognostic (2.13e-1)" "unprognostic (3.52e-2)" "unprognostic (2.40e-2)" "unprognostic (4.53e-2)" "unprognostic (2.88e-2)" "unprognostic (1.40e-2)" "unprognostic (7.97e-3)" "unprognostic (8.84e-3)" "unprognostic (5.09e-2)" "prognostic favorable (1.41e-4)" "unprognostic (4.31e-2)" "prognostic unfavorable (8.83e-4)" "unprognostic (7.82e-2)" "unprognostic (1.47e-1)" "unprognostic (1.45e-1)" "prognostic favorable (5.13e-5)" 65.2 75.5 51.4 43.7 50.5 45.8 58.3 56.9 96.4 108.2 53.0 81.5 43.4 70.0 34.5 51.7 81.7 27.6 74.3 51.0 54.8 74.3 78.1 64.7 59.8 53.6 51.0 96.2 89.7 36.7 72.8 30.3 50.0 98.2 39.5 64.3 50.3 36.0 44.0 54.3 78.0 42.2 48.1 103.5 69.3 66.1 53.1 48.6 74.9 25.7 50.1 67.2 68.5 51.7 28.6 18.0 73.0 48.1 70.8 38.4 25.9 47.8 41.0 40.8 42.7 31.0 31.4 147.2 27.0 47.0 41.1 23.6 61.2 40.9 51.3 57.3 23.2 68.6 46.1 41.3 40.0 71.3 69.4 36.0 50.5 45.7 50.9 76.4 52.2 37.0 57.0 36.0 39.3 26.9 66.8 106.0 57.9 34.7 32.0 26.1 31.0 38.0 40.4 57.0 28.8 51.6 43.7 31.0 30.9 62.9 25.3 55.7 48.8 41.2 48.0 33.3 48.6 49.7 123.7 84.9 23.7 58.6 40.6 16.4 8.5 5.2 13.3 4.6 11.2 12.3 9.3 8.2 8.8 11.5 9.3 10.2 5.6 7.2 8.8 9.6 7.0 6.1 51.4 50.5 56.9 96.4 51.0 54.8 53.6 51.0 50.0 48.1 53.1 51.7 76.0 57.7 75.2 172.4 87.4 54.0 43.0 34.2 67.7 120.1 43.5 33.8 35.7 40.0 45.9 62.5 102.2 38.2 91.9 46.4 11.7 33.4 31.9 51.2 69.5 57.2 47.3 51.9 195.6 28.0 33.0 53.9 64.7 46.3 43.0 93.0 45.7 36.0 27.8 92.5 216.8 44.5 36.7 56.1 82.2 25.2 65.6 50.1 60.5 161.1 66.1 43.4 62.8 154.3 177.9 34.3 32.4 60.5 106.9 51.2 60.9 17.7 49.1 145.7 46.0 55.6 63.7 135.3 56.7 46.7 45.3 36.3 66.4 66.3 39.5 35.2 RBM8A "BOV-1A, BOV-1B, BOV-1C, RBM8, RBM8B, Y14, ZNRP" ENSG00000265241 "RNA binding motif protein 8A" Q9Y5S9 1 145917714-145927678 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA processing, mRNA splicing, mRNA transport, Nonsense-mediated mRNA decay, Translation regulation, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 735.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018403 Supported Supported "Nuclear speckles" NA NA 100000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Nuclear speckles" "HPA018403: AB_1858908" "unprognostic (3.81e-1)" "unprognostic (3.99e-3)" "unprognostic (1.59e-1)" "unprognostic (6.83e-2)" "unprognostic (1.12e-1)" "unprognostic (3.16e-1)" "unprognostic (4.62e-3)" "unprognostic (1.91e-1)" "unprognostic (1.38e-1)" "unprognostic (8.79e-3)" "unprognostic (7.27e-3)" "prognostic unfavorable (1.55e-4)" "unprognostic (3.30e-3)" "unprognostic (2.18e-1)" "unprognostic (3.77e-2)" "unprognostic (2.02e-1)" "unprognostic (1.64e-3)" 86.1 74.9 37.2 105.4 39.1 214.7 82.3 38.7 43.0 69.6 35.6 70.5 70.1 67.7 49.3 163.6 62.2 58.0 73.0 36.8 41.7 81.6 77.5 72.8 126.4 39.7 39.8 72.0 59.9 78.4 65.8 85.3 40.8 66.4 56.4 45.0 79.2 48.2 214.9 92.0 69.2 57.7 42.1 81.6 67.5 71.3 40.0 120.7 68.8 100.1 123.7 112.8 80.4 43.9 377.0 300.7 268.8 215.7 94.6 92.2 330.0 224.3 150.7 315.0 230.1 400.0 277.4 342.0 344.9 155.3 166.5 252.5 289.3 245.3 257.0 305.6 275.7 264.2 229.2 299.8 133.6 446.6 222.6 102.2 180.8 283.0 300.3 137.4 238.1 291.9 405.2 314.7 246.2 1033.8 452.3 352.2 463.7 323.9 518.4 394.4 234.6 341.2 203.2 355.6 274.6 335.7 334.5 169.7 316.5 231.0 318.0 534.3 247.3 252.3 324.0 250.9 626.0 352.2 603.4 502.6 226.4 264.9 223.2 464.6 316.5 513.6 337.2 363.9 322.1 444.3 317.6 346.4 318.0 389.6 296.1 328.3 363.7 389.8 361.3 498.4 386.3 582.7 37.2 39.1 38.7 43.0 36.8 41.7 39.7 39.8 40.8 42.1 40.0 43.9 289.1 70.5 132.4 8.1 251.0 332.9 396.7 475.4 244.2 66.3 168.5 184.7 78.0 98.7 262.8 88.3 54.2 376.2 276.0 125.3 187.9 224.1 243.7 148.0 134.3 206.0 158.9 149.2 10.8 223.2 506.3 174.1 80.5 152.8 244.0 136.8 120.3 124.4 204.3 35.3 9.1 127.6 313.3 100.3 265.2 54.4 102.2 170.7 208.1 9.4 197.7 120.3 165.8 6.0 16.1 245.4 159.8 85.4 174.9 259.6 119.5 204.1 195.1 86.3 98.6 213.7 208.1 212.0 168.9 208.1 318.0 735.5 282.1 139.7 141.7 393.0 RBP7 CRBPIV ENSG00000162444 "Retinol binding protein 7" Q96R05 1 9997206-10016021 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 401.0;breast: 394.6" "Cell type enriched" "Detected in many" 7 "Adipocytes: 3631.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 311.5;neutrophil: 344.7" "Group enriched" "Detected in many" 31 "granulocytes: 344.7;monocytes: 311.5" "Group enriched" "Detected in some" 4 "EFO-21: 13.0;SK-MEL-30: 9.8;T-47d: 34.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" HPA034749 Enhanced Uncertain "Nuclear speckles,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 6: T47d - Mammary gland" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles, Cytosol" "HPA034749: AB_10602084" "unprognostic (1.93e-3)" "unprognostic (1.50e-1)" "prognostic unfavorable (2.49e-4)" "unprognostic (9.59e-2)" "unprognostic (2.31e-1)" "unprognostic (6.28e-2)" "unprognostic (1.39e-2)" "unprognostic (1.85e-1)" "unprognostic (1.05e-3)" "unprognostic (2.24e-1)" "unprognostic (1.46e-2)" "unprognostic (7.90e-2)" "unprognostic (5.07e-2)" "unprognostic (2.38e-2)" "unprognostic (2.93e-1)" "unprognostic (1.15e-1)" "unprognostic (1.61e-2)" 401.0 15.0 20.7 8.9 27.0 28.6 394.6 23.8 38.3 22.6 23.4 15.0 2.6 20.4 4.2 34.4 14.7 51.6 86.6 20.4 22.4 72.9 9.6 8.8 8.3 23.7 24.0 12.7 11.9 68.9 16.7 15.9 23.7 18.6 4.4 5.0 22.3 8.1 16.0 35.4 11.5 14.9 23.5 112.1 17.2 9.2 22.4 12.6 36.2 24.9 5.6 23.6 27.9 36.4 0.0 0.6 0.3 0.0 0.0 0.5 0.0 0.0 0.0 2.5 0.9 2.5 3.2 0.0 13.0 1.3 0.0 0.0 0.1 1.0 4.4 0.0 2.8 0.0 0.1 1.3 1.6 0.0 0.0 0.0 2.0 2.1 0.0 2.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 3.4 0.0 0.0 0.0 0.7 0.0 0.2 0.5 2.6 0.2 9.8 3.5 34.8 2.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.4 311.5 2.8 0.4 138.4 0.2 0.1 0.0 0.1 10.6 0.2 0.2 0.1 344.7 0.0 68.3 2.0 0.7 96.8 20.7 27.0 23.8 38.3 20.4 22.4 23.7 24.0 23.7 23.5 22.4 36.4 3631.8 0.0 1.3 0.7 9.5 20.6 9.5 2.6 9.1 0.2 43.0 73.9 22.9 10.0 1.2 1.8 0.0 5.0 16.2 0.1 23.5 2.0 3.2 2.5 15.8 349.2 0.0 5.7 0.4 2.8 1.9 36.1 0.0 4.8 3.8 7.1 69.7 3.7 63.7 0.0 0.4 0.4 2.0 502.5 14.1 6.1 6.2 42.5 21.4 1.0 149.7 2.1 3.1 0.0 13.4 2.7 0.1 0.7 2.7 20.7 0.0 1.4 0.9 1.5 0.0 3.9 20.5 1.8 2.8 26.2 17.6 6.2 3.8 3.6 0.6 6.3 RCAN3 DSCR1L2 ENSG00000117602 "RCAN family member 3" Q9UKA8 1 24502351-24541040 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 33.8" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 88.0;Enteroendocrine cells: 82.1;T-cells: 106.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 38.2" "Lineage enriched" "Detected in all" 7 "T-cells: 38.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034533, HPA064289" Enhanced Approved "Nucleoli fibrillar center,Nuclear speckles" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 34: Non-specific - Transcription" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles" "Nucleoli fibrillar center" "HPA034533: AB_10601481, HPA064289: AB_2685232" "unprognostic (1.55e-3)" "unprognostic (1.58e-2)" "unprognostic (4.01e-2)" "unprognostic (1.51e-3)" "unprognostic (1.20e-1)" "unprognostic (4.20e-3)" "unprognostic (3.41e-3)" "unprognostic (3.66e-2)" "unprognostic (6.42e-2)" "unprognostic (2.47e-1)" "unprognostic (1.72e-3)" "unprognostic (7.44e-2)" "unprognostic (3.52e-3)" "unprognostic (9.83e-2)" "unprognostic (9.19e-2)" "unprognostic (1.68e-2)" "unprognostic (4.71e-2)" 3.7 1.9 3.3 12.3 4.0 7.0 7.1 27.0 4.7 4.5 3.2 6.7 6.9 3.0 6.4 12.4 14.4 5.5 3.4 1.8 7.3 3.9 1.7 8.0 19.9 9.3 7.3 0.6 15.7 6.3 6.3 2.1 9.3 33.8 6.7 11.5 11.6 2.3 1.8 11.2 6.1 3.5 4.5 9.3 17.2 2.1 6.6 16.1 12.3 3.0 19.5 7.0 6.0 6.9 17.6 13.9 0.2 4.3 3.5 8.4 15.6 11.8 6.4 9.5 9.0 4.3 23.0 13.1 10.8 19.9 7.4 16.4 12.0 14.8 10.2 12.9 7.3 1.4 3.8 13.1 2.2 4.6 11.5 2.9 10.8 3.8 4.6 7.9 1.9 16.2 2.0 0.5 4.1 6.3 12.1 6.7 17.7 13.4 10.2 4.7 0.2 0.4 6.9 17.9 35.6 8.8 9.7 12.0 37.2 7.9 12.8 8.9 13.6 11.2 13.2 0.6 8.2 18.2 22.8 17.5 4.5 18.0 12.9 3.5 1.8 2.2 1.2 1.0 10.0 5.2 24.9 9.0 3.0 5.1 33.1 17.7 0.6 4.0 0.4 2.1 38.2 7.9 3.3 4.0 27.0 4.7 1.8 7.3 9.3 7.3 9.3 4.5 6.6 6.9 19.7 19.2 13.3 0.0 32.4 14.1 27.3 8.9 11.4 43.0 29.9 36.8 6.4 25.8 15.8 20.2 64.6 4.0 18.9 16.4 13.7 19.0 1.2 88.0 6.8 8.6 82.1 2.5 1.6 28.2 10.3 6.0 26.5 34.1 16.5 14.8 7.1 2.2 8.5 25.2 6.7 14.4 14.2 8.4 28.0 0.0 1.8 23.0 30.2 5.6 31.5 9.1 6.2 0.0 21.2 43.2 11.3 1.2 22.0 53.9 4.3 1.0 67.7 34.5 0.0 4.7 10.4 0.7 17.5 26.9 21.7 5.3 106.8 0.1 12.2 26.3 RFPL1 RNF78 ENSG00000128250 "Ret finger protein like 1" O75677 22 29438583-29442455 "Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.3;retina: 3.0" "Group enriched" "Detected in some" 7 "Early spermatids: 9.1;Hepatic stellate cells: 8.6" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebral cortex: 10.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 7.5;HMC-1: 2.7;Karpas-707: 3.0;SH-SY5Y: 3.7;SiHa: 1.8;THP-1: 3.5" "HPA048320, HPA072380" Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 58: Brain - Synaptic function" "Cluster 44: HDLM-2 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Nuclear speckles" "Plasma membrane" "HPA048320: AB_2680356, HPA072380: AB_2686515" "unprognostic (4.54e-1)" "unprognostic (6.63e-8)" "unprognostic (3.14e-3)" "unprognostic (1.89e-1)" 0.1 2.9 2.5 0.2 2.3 0.0 0.0 0.0 10.3 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.2 0.0 4.1 0.0 0.0 1.1 0.0 0.2 0.0 0.0 2.5 0.1 0.2 0.3 0.1 0.0 1.3 0.0 3.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.6 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 7.5 0.5 0.0 0.6 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.0 0.0 0.1 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.7 1.8 0.0 0.0 0.1 0.0 3.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.1 0.5 0.0 0.1 0.0 0.0 0.3 0.0 0.2 0.1 2.5 2.3 0.0 10.3 4.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.4 0.0 0.0 0.8 0.0 0.0 1.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 RFPL2 RNF79 ENSG00000128253 "Ret finger protein like 2" O75678 22 32190435-32205001 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 8 "brain: 10.2;prostate: 3.8" "Group enriched" "Detected in some" 4 "Excitatory neurons: 17.6;Inhibitory neurons: 8.6" "Cancer enriched" "Detected in single" 15 "prostate cancer: 5.6" "Region enriched" "Detected in many" 4 "cerebral cortex: 10.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046608, HPA048320, HPA072380" Approved Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear speckles" "Plasma membrane" "HPA046608: , HPA048320: AB_2680356, HPA072380: AB_2686515" "unprognostic (3.81e-2)" "unprognostic (4.05e-2)" "unprognostic (8.29e-2)" "unprognostic (9.66e-3)" "unprognostic (2.54e-1)" "unprognostic (9.90e-2)" "unprognostic (2.59e-1)" "unprognostic (6.02e-3)" "unprognostic (2.22e-2)" "unprognostic (3.44e-2)" "unprognostic (8.64e-3)" "prognostic favorable (4.16e-4)" "unprognostic (2.04e-4)" "unprognostic (6.02e-2)" "unprognostic (3.28e-2)" "unprognostic (5.62e-7)" "unprognostic (3.50e-2)" 0.0 0.5 1.5 0.0 1.9 0.4 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.9 0.0 0.1 0.0 0.1 1.7 0.7 0.3 0.0 0.0 0.1 0.0 1.7 3.8 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.7 0.2 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.9 0.0 10.2 2.3 0.9 1.7 0.7 1.7 0.0 1.0 1.6 0.1 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.7 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 2.7 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.5 1.2 0.0 0.0 0.0 0.0 3.1 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 RFPL3 RNF120 ENSG00000128276 "Ret finger protein like 3" O75679 22 32354885-32361161 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 24.8" "Cell type enhanced" "Detected in some" "Early spermatids: 2.6;Spermatocytes: 2.0;Spermatogonia: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.6;NB-4: 2.2;U-266/70: 2.5;U-266/84: 2.6" "HPA048320, HPA072380" Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 24: NB-4 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" "Plasma membrane" "HPA048320: AB_2680356, HPA072380: AB_2686515" "unprognostic (1.63e-1)" "unprognostic (9.90e-2)" "unprognostic (1.10e-1)" "unprognostic (1.05e-1)" "unprognostic (1.52e-2)" "unprognostic (1.97e-1)" "unprognostic (3.25e-2)" "unprognostic (4.31e-2)" "unprognostic (1.90e-1)" "unprognostic (6.32e-2)" 0.1 0.1 0.0 0.2 0.1 1.4 0.0 0.5 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.3 0.1 0.2 0.0 0.0 0.1 0.1 0.6 0.1 0.1 0.5 0.7 0.0 0.1 0.1 0.1 0.3 0.0 2.4 0.5 0.0 0.5 1.3 0.3 0.0 0.0 0.7 0.1 24.8 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.4 1.0 0.3 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 1.0 0.5 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.8 0.0 0.8 0.0 0.4 0.6 2.2 0.1 0.1 0.0 1.1 0.2 0.3 0.0 0.2 0.8 0.1 0.0 0.2 0.6 0.2 0.0 0.2 0.0 0.0 0.4 0.1 0.0 2.5 2.6 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.2 0.2 0.0 0.1 0.1 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 RFXAP ENSG00000133111 "Regulatory factor X associated protein" O00287 13 36819222-36829104 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" DNA-binding SCID "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032035 Approved "Nuclear speckles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "HPA032035: AB_2674120" "unprognostic (2.03e-1)" "unprognostic (9.69e-2)" "unprognostic (7.40e-2)" "unprognostic (3.13e-1)" "unprognostic (5.14e-3)" "unprognostic (4.45e-3)" "unprognostic (1.15e-2)" "prognostic favorable (2.26e-5)" "unprognostic (1.45e-1)" "unprognostic (2.94e-1)" "prognostic favorable (4.18e-4)" "unprognostic (1.43e-1)" "unprognostic (1.15e-1)" "prognostic favorable (4.91e-4)" "unprognostic (2.81e-2)" "unprognostic (4.09e-1)" "unprognostic (5.99e-3)" 4.3 3.4 3.8 5.0 4.2 6.0 4.7 6.8 5.2 6.3 2.5 5.1 3.1 6.8 5.1 3.0 5.8 4.1 3.5 3.9 3.5 3.3 2.6 4.3 6.7 3.3 3.7 7.0 4.6 6.2 4.6 3.7 3.5 5.2 4.1 5.5 4.8 3.8 4.3 3.5 4.4 5.8 4.0 5.1 4.2 6.5 3.4 8.3 5.8 3.0 5.4 4.0 3.8 4.3 7.4 1.8 10.4 14.7 3.8 5.2 6.7 5.9 6.2 10.9 6.7 5.2 5.9 32.3 4.8 5.4 9.6 6.7 10.8 3.6 12.2 24.4 17.9 15.5 8.6 10.2 6.9 28.7 10.9 4.8 6.3 5.3 4.0 3.1 8.3 24.4 9.0 6.4 3.3 3.6 28.8 20.5 11.1 6.4 3.2 24.9 19.3 9.8 4.6 4.5 8.5 10.6 5.7 3.8 4.7 6.3 3.9 16.9 6.5 2.8 6.1 9.8 5.5 6.0 5.3 24.2 7.9 19.6 4.5 0.0 0.0 0.5 0.2 0.0 0.1 0.3 0.1 0.2 0.0 0.1 0.1 0.2 0.0 0.1 0.1 0.3 0.2 0.0 3.8 4.2 6.8 5.2 3.9 3.5 3.3 3.7 3.5 4.0 3.4 4.3 6.6 3.2 3.9 11.1 10.4 3.6 3.3 2.5 7.4 14.5 4.9 4.4 3.6 1.5 2.7 3.7 2.1 6.4 11.1 2.0 15.6 4.2 5.3 4.3 7.5 7.0 7.2 16.0 26.4 5.5 2.8 9.8 4.6 3.0 10.2 10.9 7.9 2.2 3.1 23.5 27.5 2.8 2.0 1.9 7.4 4.1 11.1 4.1 7.2 7.5 5.5 20.8 17.5 11.1 23.9 2.8 2.5 10.9 6.4 1.5 3.3 1.4 2.2 18.0 6.6 13.1 10.0 20.1 25.8 2.8 2.0 1.2 11.7 8.2 3.6 0.8 RMI2 "BLAP18, C16orf75, MGC24665" ENSG00000175643 "RecQ mediated genome instability 2" Q96E14 16 11249619-11381662 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "DNA replication" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 36.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 123.8;Erythroid cells: 38.5;Extravillous trophoblasts: 34.1;Peritubular cells: 42.5;Spermatocytes: 36.6;Spermatogonia: 51.8;Syncytiotrophoblasts: 47.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 4.2" "Group enriched" "Detected in many" 6 "B-cells: 4.2;T-cells: 1.4" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA040995 Uncertain Supported "Nuclear speckles,Cytosol" NA Yes "Cluster 37: B-cells - Transcription" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nuclear speckles" Cytosol "HPA040995: AB_10795531" "unprognostic (2.76e-1)" "prognostic favorable (5.69e-5)" "unprognostic (1.17e-1)" "unprognostic (3.09e-3)" "unprognostic (1.69e-2)" "unprognostic (1.80e-3)" "prognostic unfavorable (2.77e-5)" "unprognostic (3.98e-1)" "unprognostic (1.16e-1)" "unprognostic (1.83e-1)" "unprognostic (3.44e-3)" "unprognostic (3.89e-1)" "unprognostic (2.18e-1)" "unprognostic (5.50e-2)" "unprognostic (3.68e-2)" "unprognostic (3.60e-3)" "unprognostic (1.03e-1)" 1.4 1.5 2.2 12.3 2.0 9.9 5.1 1.0 2.2 4.8 0.9 12.5 7.5 2.9 3.9 10.8 2.1 2.2 1.6 2.3 1.3 3.4 4.3 1.9 31.4 1.2 1.3 3.0 1.8 1.3 0.6 19.3 1.2 3.2 14.4 0.5 2.4 2.1 0.9 10.2 8.8 2.3 1.0 3.5 7.0 14.0 1.4 36.8 1.5 0.6 34.9 4.5 4.4 1.8 60.3 39.5 75.2 32.6 3.3 15.8 33.0 35.9 26.8 31.6 51.8 15.4 69.2 83.8 29.1 15.8 35.3 34.4 32.4 32.5 50.5 16.6 30.5 45.3 22.6 102.5 1.3 17.6 19.5 3.7 6.1 14.5 13.3 12.3 17.4 36.2 65.3 63.2 16.5 70.3 60.9 83.1 64.1 82.6 15.7 73.1 81.1 89.3 18.7 38.0 44.1 35.0 28.5 47.4 26.1 43.5 80.4 25.8 5.6 25.1 23.3 49.3 5.0 18.1 30.9 99.3 23.3 57.4 47.2 0.0 0.0 0.4 0.3 0.0 0.0 4.2 0.1 0.0 0.2 1.1 0.8 0.3 0.1 0.1 0.0 0.2 1.4 0.1 2.2 2.0 1.0 2.2 2.3 1.3 1.2 1.3 1.2 1.0 1.4 1.8 1.3 0.0 0.5 0.0 4.5 6.8 5.4 1.4 6.2 0.2 3.4 3.2 1.0 4.3 1.6 7.3 0.0 123.8 0.5 3.3 5.9 2.6 3.0 0.8 2.1 2.8 2.4 38.5 0.0 0.5 34.1 6.4 4.1 2.2 0.0 19.7 1.1 1.1 18.5 0.0 0.0 7.7 0.0 0.8 6.5 5.9 15.8 3.7 3.6 0.0 1.1 0.2 1.0 0.0 0.0 1.0 4.0 42.5 2.4 2.1 1.3 0.4 0.1 0.6 32.9 0.0 2.2 36.6 51.8 11.3 5.4 47.7 1.9 6.5 10.3 7.5 RNF112 "BFP, ZNF179" ENSG00000128482 "Ring finger protein 112" Q9ULX5 17 19411125-19417276 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Neurogenesis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.8" "Cell type enhanced" "Detected in some" "Astrocytes: 8.1;Bipolar cells: 6.6;Excitatory neurons: 19.6;Inhibitory neurons: 11.6;Muller glia cells: 7.6;Oligodendrocyte precursor cells: 13.6;Sertoli cells: 6.6" "Cancer enriched" "Detected in some" 8 "glioma: 6.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 5.2;fHDF/TERT166: 6.2;SCLC-21H: 6.0;SH-SY5Y: 10.6;U-87 MG: 34.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA015970 Enhanced Approved "Nuclear speckles" NA NA "Cluster 65: Brain - Ion transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear speckles" "HPA015970: AB_1859103" "unprognostic (1.16e-1)" "unprognostic (3.74e-1)" "unprognostic (8.43e-5)" "unprognostic (3.65e-2)" "unprognostic (2.96e-2)" "unprognostic (6.02e-2)" "unprognostic (1.27e-1)" "unprognostic (2.88e-1)" "unprognostic (4.26e-1)" "unprognostic (5.02e-2)" "unprognostic (3.17e-1)" "unprognostic (2.96e-1)" "unprognostic (1.31e-9)" "unprognostic (1.32e-1)" "unprognostic (1.07e-1)" "unprognostic (1.59e-1)" "unprognostic (4.24e-1)" 2.2 5.4 20.2 1.5 21.9 0.1 1.9 33.8 25.0 3.2 7.2 9.4 1.8 3.0 4.5 1.7 3.2 2.8 3.6 24.7 16.8 3.9 1.0 2.8 0.7 12.7 14.2 2.4 1.3 0.0 5.5 0.5 14.0 12.3 2.8 1.5 1.2 2.0 1.3 1.9 6.9 2.2 12.9 3.0 2.5 2.3 16.6 0.2 2.2 1.3 0.2 8.4 3.2 23.2 0.0 0.0 0.1 0.4 1.4 5.2 0.2 0.3 1.2 0.1 0.0 0.2 0.0 0.0 0.1 6.2 0.0 0.2 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 4.2 0.0 0.1 2.1 0.2 0.2 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.0 0.4 0.1 0.2 0.2 0.0 0.0 6.0 10.6 0.1 0.0 0.0 1.4 0.1 0.1 0.1 0.0 0.3 0.6 0.0 0.1 0.0 0.0 34.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.2 21.9 33.8 25.0 24.7 16.8 12.7 14.2 14.0 12.9 16.6 23.2 1.1 0.0 0.0 8.1 0.0 1.0 0.0 0.2 0.0 6.6 0.1 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.1 0.2 0.3 0.5 0.0 0.0 19.6 0.0 0.0 3.3 0.0 0.2 0.0 0.8 0.0 0.0 0.0 0.0 11.6 0.2 0.0 0.6 0.4 0.2 0.0 0.3 0.0 4.7 0.1 7.6 1.0 13.6 3.3 0.0 1.4 3.8 0.0 0.2 0.5 0.0 0.1 0.7 6.6 1.4 1.5 1.7 0.7 0.3 1.0 0.3 0.2 0.0 0.1 0.1 RNF151 ENSG00000179580 "Ring finger protein 151" Q2KHN1 16 1966823-1968975 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 411 "testis: 190.2" "Group enriched" "Detected in some" 137 "Early spermatids: 2202.5;Late spermatids: 1521.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA055054 Approved "Nuclear speckles,Vesicles,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 74: Testis - Spermatogenesis" "Cluster 34: Spermatids - Unknown function" Cytosol "Nuclear speckles, Vesicles" "HPA055054: " "unprognostic (1.47e-1)" "unprognostic (1.24e-1)" "unprognostic (2.54e-2)" "unprognostic (1.18e-1)" "unprognostic (5.65e-2)" "unprognostic (4.01e-3)" "unprognostic (1.15e-1)" "unprognostic (1.22e-1)" "unprognostic (1.41e-1)" "unprognostic (3.20e-1)" "unprognostic (4.39e-3)" "unprognostic (4.63e-1)" "unprognostic (1.98e-4)" "unprognostic (1.46e-1)" "unprognostic (4.19e-2)" "unprognostic (1.10e-1)" "unprognostic (2.43e-2)" 0.0 0.0 0.1 0.1 0.2 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 190.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.1 0.4 0.4 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.3 0.1 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.2 0.2 0.1 0.2 0.0 0.2 0.3 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.2 0.3 0.1 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2202.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1521.4 9.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.1 0.0 0.0 6.6 0.2 0.1 13.5 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 RPL3L ENSG00000140986 "Ribosomal protein L3 like" Q92901 16 1943974-1957606 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 943.6;tongue: 422.7" "Cell type enriched" "Detected in some" 5 "Cardiomyocytes: 134.5" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.4" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "CACO-2: 4.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA049136 Enhanced Approved "Nuclear speckles" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 39: CACO-2 - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nuclear speckles" "HPA049136: AB_2680648" "unprognostic (2.53e-1)" "unprognostic (2.63e-2)" "unprognostic (9.27e-4)" "unprognostic (6.38e-4)" "unprognostic (4.36e-2)" "unprognostic (3.48e-3)" "unprognostic (3.46e-2)" "unprognostic (2.14e-1)" "unprognostic (1.17e-1)" "unprognostic (1.19e-2)" "unprognostic (2.00e-1)" "unprognostic (2.46e-2)" "unprognostic (4.53e-3)" "unprognostic (3.32e-1)" "unprognostic (4.24e-1)" "unprognostic (8.32e-3)" "unprognostic (4.60e-2)" 0.3 0.4 0.9 0.2 0.6 1.7 1.4 1.7 0.8 0.0 1.0 0.2 0.6 0.3 0.4 8.5 0.1 0.5 174.0 0.5 0.4 0.4 0.3 0.2 0.4 0.1 0.0 0.3 11.5 0.0 0.1 0.2 0.1 4.2 0.0 1.2 6.9 0.1 943.6 0.7 0.5 0.0 0.0 0.4 0.2 6.4 0.1 0.1 0.4 422.7 0.1 0.2 0.1 1.0 1.1 1.2 0.3 1.1 0.0 0.0 0.7 0.5 0.0 0.0 0.0 4.0 2.1 0.6 0.7 0.0 1.0 1.1 0.1 0.1 0.0 0.5 0.6 0.4 0.9 1.4 0.0 0.3 0.4 0.1 0.1 0.1 0.1 0.7 0.0 0.7 0.4 2.8 0.0 0.6 0.8 1.0 0.6 1.2 2.5 0.4 0.3 0.9 0.1 0.4 1.6 0.5 0.5 1.4 0.6 0.7 0.7 0.6 0.6 0.6 1.4 0.8 0.4 1.2 0.6 0.5 0.8 0.2 0.2 0.5 0.2 0.3 0.3 0.3 0.2 0.4 0.2 0.3 0.1 0.4 0.3 0.3 1.2 0.2 0.3 0.4 0.1 0.1 0.9 0.6 1.7 0.8 0.5 0.4 0.1 0.0 0.1 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.6 0.9 0.2 0.0 0.0 0.1 0.6 134.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 7.9 0.0 0.1 1.3 0.0 5.3 0.1 0.0 0.2 2.9 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 7.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 23.7 2.2 0.7 2.4 0.0 0.4 0.0 0.2 0.1 0.1 0.5 RPLP2 "D11S2243E, LP2, MGC71408, P2, RPP2" ENSG00000177600 "Ribosomal protein lateral stalk subunit P2" P05387 11 809965-812880 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053635, HPA075365" Approved Approved "Nuclear speckles,Mitotic spindle,Cytosol" "Intracellular and membrane" Yes NA 2900000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 32: Non-specific - Translation" "Nuclear speckles, Cytosol" "Mitotic spindle" "HPA053635: AB_2682212, HPA075365: " "unprognostic (6.98e-3)" "unprognostic (2.21e-1)" "unprognostic (4.57e-2)" "unprognostic (8.63e-2)" "unprognostic (2.30e-2)" "unprognostic (2.39e-1)" "prognostic unfavorable (9.14e-4)" "unprognostic (1.63e-1)" "unprognostic (2.98e-1)" "unprognostic (1.93e-1)" "unprognostic (2.08e-1)" "unprognostic (2.99e-1)" "prognostic unfavorable (2.19e-6)" "unprognostic (6.52e-2)" "unprognostic (1.67e-1)" "unprognostic (1.16e-1)" "unprognostic (3.31e-2)" 2013.7 831.3 1119.2 993.1 1162.5 2166.9 1656.6 1099.7 1368.9 1256.2 1084.1 1277.1 1016.8 930.2 701.6 1241.3 1240.4 564.0 869.3 1057.5 1116.3 885.0 657.0 851.0 1924.7 1138.0 1095.8 2092.8 2087.8 545.7 595.5 830.9 1154.3 925.8 887.8 180.9 1908.3 775.7 1802.7 1760.4 1191.7 624.4 1204.8 1543.8 1006.0 377.6 1167.5 1545.7 785.0 936.1 1715.4 1075.5 1137.9 1217.7 2773.5 2229.6 1070.4 1864.1 2343.2 2458.2 2389.5 1728.2 1285.0 2090.8 1638.4 3307.6 2218.5 3851.6 1225.0 1629.9 1107.9 2546.7 1786.2 2778.3 836.3 1713.6 8117.9 1901.7 1416.9 3996.4 2837.3 3540.8 1905.4 3393.9 4684.6 764.1 2182.7 1860.8 2111.9 2798.2 3432.2 2040.5 1317.9 2656.6 2969.5 6002.3 3188.8 3394.5 6045.3 3345.1 1465.6 4369.9 1759.0 1281.0 2222.2 3142.1 1118.5 2825.8 3582.4 885.1 1198.9 3577.2 1881.2 1142.3 1393.9 964.1 1981.6 3838.4 3778.8 3419.3 1790.5 2952.3 1340.6 1565.3 3908.1 1299.1 4402.2 3129.1 6208.3 10718.3 8296.0 6323.4 4273.6 9867.1 10158.6 8083.9 529.9 4310.4 2525.7 5882.9 5140.5 13330.7 1119.2 1162.5 1099.7 1368.9 1057.5 1116.3 1138.0 1095.8 1154.3 1204.8 1167.5 1217.7 1311.8 1067.3 1685.0 16.3 5889.9 6113.3 6658.4 2808.0 2619.1 206.2 5955.7 4736.9 638.4 2505.0 1972.2 1601.9 79.2 5046.4 3469.2 2296.4 2592.4 3688.3 1403.0 1105.9 2434.1 2724.8 2370.2 3482.2 18.6 7413.9 8045.8 2074.3 1401.2 1787.6 1721.9 1543.2 4028.6 3068.9 4514.0 146.4 17.8 5925.5 870.8 5458.4 6404.8 3133.4 6393.4 3169.4 2986.4 27.2 5854.8 1052.2 5787.9 6.0 19.0 5201.1 4547.7 2821.7 2403.4 6640.3 4473.8 4234.1 900.4 235.5 1991.9 3688.9 2346.3 1123.1 2093.1 4264.4 7887.4 5841.1 4889.3 1629.7 6189.1 7014.0 RREB1 HNT ENSG00000124782 "Ras responsive element binding protein 1" Q92766 6 7107597-7251980 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001756, HPA034843" Approved Supported "Nucleoli fibrillar center,Nuclear speckles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 1: K-562 - Erythropoiesis" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nuclear speckles" "Nucleoli fibrillar center" "HPA001756: AB_1856477, HPA034843: AB_2674357" "unprognostic (1.69e-1)" "unprognostic (3.16e-2)" "unprognostic (2.93e-1)" "unprognostic (5.05e-2)" "unprognostic (7.38e-2)" "unprognostic (1.23e-3)" "unprognostic (2.53e-1)" "unprognostic (1.32e-2)" "unprognostic (2.45e-2)" "unprognostic (6.51e-2)" "unprognostic (3.31e-2)" "unprognostic (1.16e-1)" "prognostic favorable (1.41e-4)" "unprognostic (1.21e-2)" "unprognostic (1.60e-1)" "unprognostic (9.54e-2)" "unprognostic (2.92e-1)" 10.9 12.1 4.3 7.8 3.6 31.6 10.8 4.4 2.2 10.2 12.5 10.8 11.9 7.8 5.6 26.2 8.7 6.4 8.3 2.7 4.2 8.2 18.3 9.1 6.5 9.1 6.6 9.8 18.1 12.2 6.3 8.1 6.5 8.1 9.8 5.7 15.0 6.2 16.6 16.2 13.1 6.2 5.4 10.7 10.7 11.6 7.6 9.2 12.0 7.9 7.9 7.9 14.2 5.5 13.1 12.3 10.3 11.9 9.5 6.3 40.1 5.2 7.3 6.2 7.6 20.3 10.0 6.6 10.9 9.9 6.9 9.3 14.7 16.5 5.9 9.2 11.3 24.8 9.6 23.5 13.1 15.0 18.5 10.5 12.7 9.3 13.8 4.2 7.5 15.2 44.6 0.1 6.5 16.5 8.8 35.2 4.9 10.6 10.0 13.1 12.4 10.4 9.0 25.1 2.8 2.6 12.4 16.0 11.1 15.3 12.3 31.0 13.0 11.4 7.1 8.8 6.4 4.1 4.7 9.0 3.3 11.4 9.3 5.5 2.7 6.6 1.5 2.1 1.3 2.2 1.0 1.0 1.7 1.0 1.6 1.3 2.0 3.3 2.4 5.7 0.5 1.7 4.3 3.6 4.4 2.2 2.7 4.2 9.1 6.6 6.5 5.4 7.6 5.5 39.3 25.6 28.7 44.4 19.0 31.5 22.4 30.1 27.9 0.9 27.0 16.9 24.2 31.5 31.4 36.8 70.9 25.8 31.9 62.7 7.9 14.7 46.2 35.5 24.7 22.5 31.8 31.1 3.9 16.3 32.8 16.3 30.1 63.0 10.1 20.7 30.7 70.4 33.4 0.0 0.7 35.7 14.2 66.1 54.9 9.0 19.9 42.1 23.2 78.7 32.6 9.5 13.4 2.0 0.9 22.3 36.3 19.2 27.7 37.1 34.5 16.8 23.9 27.5 52.6 25.5 15.2 13.7 17.4 48.9 34.7 45.8 15.7 27.4 45.0 54.3 RSBN1L "FLJ42526, FLJ45813, MGC71764" ENSG00000187257 "Round spermatid basic protein 1 like" Q6PCB5 7 77696459-77783022 "Cancer-related genes, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 349.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 60.6" "Lineage enriched" "Detected in all" 4 "granulocytes: 60.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020406, HPA020413" Approved Supported "Nuclear speckles,Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "Plasma membrane" "HPA020406: AB_1856488, HPA020413: AB_2253910" "unprognostic (2.02e-1)" "unprognostic (2.61e-2)" "unprognostic (2.41e-1)" "unprognostic (1.72e-1)" "unprognostic (1.34e-1)" "unprognostic (3.62e-2)" "unprognostic (2.43e-2)" "prognostic favorable (3.74e-4)" "unprognostic (1.27e-2)" "unprognostic (3.78e-2)" "unprognostic (1.25e-1)" "unprognostic (9.02e-2)" "unprognostic (7.30e-3)" "unprognostic (1.93e-1)" "unprognostic (1.46e-1)" "unprognostic (2.25e-3)" "unprognostic (1.53e-3)" 7.3 6.4 8.7 11.5 9.1 8.2 12.1 19.0 12.1 10.3 10.2 11.3 9.0 12.5 10.3 10.8 9.5 7.3 5.6 8.5 10.5 9.1 11.3 10.5 16.1 8.2 9.0 14.5 11.2 10.3 6.9 9.9 8.6 10.3 11.7 30.2 9.6 11.4 8.2 7.8 10.4 11.0 9.0 15.0 11.0 26.3 8.6 18.3 16.5 7.6 15.0 9.6 8.2 11.6 15.8 11.9 19.6 34.5 13.4 17.0 9.5 11.5 12.4 16.0 18.2 14.9 27.6 32.4 4.4 12.0 20.2 13.4 26.8 15.0 22.8 17.7 14.4 25.8 18.4 14.7 11.3 32.1 23.3 12.2 10.7 14.7 16.0 12.1 13.5 21.2 35.7 33.0 16.8 18.2 27.7 32.1 14.0 20.3 10.6 28.3 19.6 34.2 10.0 20.5 22.9 24.0 17.5 31.4 12.6 19.9 19.2 16.9 12.9 23.9 21.9 14.5 17.7 14.7 16.7 51.6 11.4 29.2 16.0 21.6 7.4 13.5 9.5 5.8 7.3 11.0 8.4 7.1 4.4 13.5 7.8 8.6 60.6 6.4 6.7 13.9 9.3 2.6 8.7 9.1 19.0 12.1 8.5 10.5 8.2 9.0 8.6 9.0 8.6 11.6 53.6 57.7 60.3 27.1 85.0 78.8 102.1 76.1 88.8 246.8 52.1 57.3 22.1 61.5 84.4 55.2 235.6 52.7 101.5 77.1 39.2 38.1 271.3 55.5 63.3 60.8 77.5 47.7 44.3 50.4 34.1 55.6 51.5 45.6 70.3 51.3 49.2 56.5 43.7 158.2 47.5 104.6 57.0 48.1 69.0 85.2 101.5 46.4 64.0 34.7 59.0 83.2 132.8 53.8 50.1 35.1 62.7 119.6 74.6 56.7 49.6 28.4 72.0 349.9 72.3 44.2 73.0 108.0 156.7 56.2 75.3 38.7 90.2 61.7 79.1 84.0 RSRC1 "BM-011, MGC12197, SFRS21, SRrp53" ENSG00000174891 "Arginine and serine rich coiled-coil 1" Q96IZ7 3 158105855-158545730 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044792 Supported Approved "Nuclear speckles" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" "Nuclear speckles" "HPA044792: AB_10794502" "unprognostic (1.06e-2)" "unprognostic (8.83e-3)" "unprognostic (1.96e-1)" "prognostic unfavorable (7.40e-5)" "unprognostic (5.18e-1)" "unprognostic (1.17e-1)" "unprognostic (3.60e-3)" "unprognostic (2.91e-2)" "unprognostic (2.86e-2)" "unprognostic (5.71e-2)" "unprognostic (2.53e-3)" "unprognostic (8.84e-2)" "unprognostic (7.98e-3)" "unprognostic (3.48e-2)" "unprognostic (9.71e-2)" "unprognostic (2.71e-1)" "unprognostic (2.15e-1)" 18.5 17.1 13.2 11.8 12.0 15.1 16.4 16.9 17.2 16.0 6.2 14.8 8.7 14.2 11.6 12.7 10.7 10.2 16.0 8.0 12.7 15.9 16.5 10.6 13.7 14.5 15.5 12.8 15.6 15.6 11.6 11.8 12.6 13.1 13.5 18.7 13.5 12.3 19.3 12.9 10.2 13.8 11.0 11.8 12.1 11.3 17.6 13.2 17.0 11.0 14.2 13.6 13.4 13.8 73.6 37.3 24.1 32.1 60.7 41.4 34.1 36.2 29.3 37.8 41.5 51.8 56.8 68.6 66.9 42.9 47.2 32.8 48.4 31.8 58.3 107.6 40.4 71.0 30.4 41.3 9.3 61.5 43.2 32.3 30.0 32.4 29.1 43.4 17.7 38.8 45.4 50.2 31.6 63.7 43.2 41.5 21.4 44.3 33.4 54.7 45.4 86.1 29.5 23.8 47.4 51.7 40.7 26.6 44.6 27.1 59.2 51.7 20.3 52.6 31.6 63.3 69.4 41.0 51.0 72.6 48.5 79.5 61.2 40.4 36.3 20.3 25.1 38.6 25.9 49.5 25.6 24.3 22.0 45.5 23.9 25.7 25.4 17.7 37.2 62.3 22.4 12.9 13.2 12.0 16.9 17.2 8.0 12.7 14.5 15.5 12.6 11.0 17.6 13.8 36.0 32.1 23.1 51.6 51.1 37.3 36.1 32.3 15.4 78.1 39.4 28.7 44.9 45.8 27.0 82.8 33.3 37.5 41.1 33.2 74.3 52.6 49.9 32.8 48.4 35.5 33.0 68.8 71.3 60.5 52.8 47.5 26.0 29.9 76.5 44.0 32.2 74.5 38.3 63.9 82.4 54.9 40.7 45.6 67.6 11.0 46.3 42.4 44.4 80.6 50.0 52.2 44.3 46.3 142.2 45.8 34.2 35.7 35.4 27.7 21.8 67.8 29.7 95.6 19.7 34.8 49.5 39.5 40.4 27.4 27.4 29.6 37.4 39.8 35.9 29.3 RSRC2 FLJ11021 ENSG00000111011 "Arginine and serine rich coiled-coil 2" Q7L4I2 12 122503454-122527000 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 65.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040070, HPA048183" Approved Approved "Nucleoli fibrillar center,Nuclear speckles,Cytosol" No No "Cluster 26: Non-specific - Mitochondria" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" "Nuclear speckles" "Nucleoli fibrillar center, Cytosol" "HPA040070: AB_10673430, HPA048183: AB_2680302" "unprognostic (4.76e-2)" "unprognostic (1.41e-1)" "unprognostic (1.32e-2)" "unprognostic (1.44e-1)" "unprognostic (6.42e-3)" "unprognostic (6.90e-2)" "prognostic unfavorable (2.05e-4)" "unprognostic (1.12e-1)" "unprognostic (1.01e-2)" "unprognostic (2.74e-2)" "unprognostic (3.26e-1)" "unprognostic (3.19e-2)" "unprognostic (1.06e-2)" "unprognostic (2.23e-2)" "unprognostic (8.87e-2)" "unprognostic (4.84e-2)" "unprognostic (1.53e-2)" 12.6 12.2 11.5 11.0 11.4 65.7 13.2 17.6 18.4 14.6 11.3 13.9 8.6 14.1 12.5 17.4 12.3 13.6 13.1 11.3 15.3 16.3 11.4 13.8 16.8 12.1 13.7 16.4 13.8 8.0 14.5 13.3 11.7 12.7 12.0 17.1 12.6 9.5 28.5 12.7 12.5 8.8 7.7 11.6 10.8 14.0 11.8 13.2 15.4 16.1 10.7 14.0 15.0 14.0 21.4 24.8 23.2 9.5 18.4 11.2 16.9 38.8 12.0 16.0 8.7 35.5 8.6 24.4 32.0 13.3 9.7 13.3 25.9 10.8 15.7 22.8 23.9 42.1 32.0 38.3 10.1 37.0 24.8 14.5 12.3 13.6 23.2 20.1 11.6 10.7 27.8 14.6 14.1 16.3 26.8 27.8 19.6 17.8 19.6 19.6 20.9 15.9 21.1 39.8 18.4 16.7 29.6 10.0 22.0 23.1 15.9 13.4 18.1 16.5 20.3 18.4 21.7 16.7 42.8 39.5 9.8 21.6 9.4 27.5 17.7 25.4 17.2 14.7 14.3 28.3 15.3 13.9 18.0 33.4 19.3 15.4 18.7 18.3 22.2 17.0 22.4 12.3 11.5 11.4 17.6 18.4 11.3 15.3 12.1 13.7 11.7 7.7 11.8 14.0 176.8 86.6 102.0 44.7 208.7 202.3 376.1 94.0 118.4 114.3 155.6 146.0 103.3 104.4 107.1 93.8 79.2 149.1 219.3 193.5 195.6 109.3 247.3 223.6 218.6 141.7 156.3 143.1 39.1 97.2 183.8 169.3 89.7 238.0 216.5 127.5 84.9 113.7 94.3 149.7 39.9 185.7 101.7 87.6 184.9 107.1 119.9 139.0 126.3 35.6 107.0 132.9 133.9 34.2 49.6 107.3 171.0 105.7 134.2 219.0 110.1 132.7 128.5 131.0 124.9 194.8 176.7 229.2 165.3 116.0 187.0 280.1 210.3 107.6 154.8 287.1 RTEL1 "bK3184A7.3, C20orf41, DKFZP434C013, KIAA1088, NHL, RTEL" ENSG00000258366 "Regulator of telomere elongation helicase 1" Q9NZ71 20 63657810-63696253 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Helicase, Hydrolase" "Disease variant, Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "B-cells: 1.0;Erythroid cells: 3.8;Gastric mucus-secreting cells: 3.1;Plasma cells: 3.0;Squamous epithelial cells: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020622, HPA067329, HPA078328" Approved "Nuclear speckles,Nuclear bodies" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 71: Testis - DNA repair" "Cluster 39: CACO-2 - Unknown function" "Cluster 59: Non-specific - Transcription" "Nuclear speckles, Nuclear bodies" "HPA020622: AB_2732425, HPA067329: AB_2685823, HPA078328: AB_2732380" "unprognostic (3.63e-2)" "unprognostic (8.08e-3)" "unprognostic (4.80e-2)" "unprognostic (1.12e-1)" "unprognostic (4.27e-1)" "unprognostic (9.30e-3)" "unprognostic (2.59e-1)" "unprognostic (3.64e-2)" "unprognostic (3.30e-2)" "unprognostic (9.05e-2)" "unprognostic (4.09e-2)" "unprognostic (9.50e-2)" "unprognostic (8.77e-3)" "unprognostic (1.17e-1)" "unprognostic (2.55e-1)" "unprognostic (2.80e-2)" "unprognostic (8.84e-2)" 4.9 7.0 1.3 6.1 1.6 8.2 5.2 5.7 4.7 6.8 0.5 8.5 4.8 10.0 3.0 4.6 6.2 3.0 3.9 1.2 0.9 4.1 4.8 6.0 4.2 2.9 0.6 6.4 8.6 2.8 12.2 4.2 1.8 6.7 2.1 2.5 6.3 4.5 5.4 4.5 5.8 3.1 0.2 6.1 6.6 7.6 1.2 4.8 7.8 2.3 2.4 6.5 6.0 1.5 8.3 11.7 7.9 15.5 1.6 1.7 14.5 16.8 4.5 26.0 6.6 22.2 7.0 11.0 8.6 5.2 9.8 15.3 5.5 11.1 6.1 5.5 11.0 13.8 21.2 21.5 5.7 13.4 24.1 2.2 6.0 6.4 7.9 4.9 9.0 19.6 17.4 10.4 5.8 8.7 21.3 17.5 7.8 7.1 22.3 17.2 7.4 11.6 4.1 9.7 15.7 9.3 9.3 27.5 2.2 3.6 7.2 15.2 12.1 29.4 9.5 10.1 13.2 9.4 4.2 7.1 7.1 9.5 10.4 0.0 1.0 0.0 0.9 1.1 0.5 0.3 0.5 0.6 1.3 0.5 0.9 0.4 0.0 0.1 1.0 1.1 0.5 0.8 1.3 1.6 5.7 4.7 1.2 0.9 2.9 0.6 1.8 0.2 1.2 1.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.6 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.5 0.6 0.0 3.8 0.0 0.0 0.0 0.4 3.1 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.2 0.0 1.1 0.1 0.0 0.7 0.0 0.0 0.0 RTL6 "dJ1033E15.2, DKFZp761O17121, LDOC1L, Mar6, Mart6, SIRH3" ENSG00000188636 "Retrotransposon Gag like 6" Q6ICC9 22 44492583-44498233 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 11.1;Collecting duct cells: 12.9;Ductal cells: 8.4;Endometrial stromal cells: 12.9;Granulosa cells: 13.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005697 Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Nuclear speckles" Cytosol "HPA005697: AB_1079244" "unprognostic (1.24e-1)" "unprognostic (1.55e-1)" "unprognostic (1.57e-2)" "unprognostic (1.65e-1)" "unprognostic (5.71e-3)" "unprognostic (1.57e-1)" "unprognostic (9.64e-3)" "unprognostic (5.40e-2)" "unprognostic (5.40e-2)" "unprognostic (2.36e-2)" "unprognostic (2.12e-1)" "unprognostic (3.57e-2)" "unprognostic (1.65e-3)" "unprognostic (1.11e-1)" "unprognostic (1.01e-1)" "unprognostic (1.82e-1)" "unprognostic (1.07e-1)" 10.6 12.1 21.3 7.2 19.2 3.2 8.9 15.1 18.9 11.2 8.3 12.5 8.8 15.7 12.1 8.2 16.6 11.0 15.3 20.1 17.4 9.3 3.2 9.4 6.3 18.8 20.0 19.2 11.0 17.8 8.7 5.1 17.1 9.8 9.1 9.6 7.2 13.6 15.5 3.4 8.4 16.9 18.8 7.5 9.7 11.2 21.9 14.2 10.2 18.0 4.8 10.4 5.4 17.2 13.8 18.9 23.9 31.9 18.3 14.8 6.3 17.9 21.1 24.6 19.2 6.3 8.0 0.0 10.9 33.5 18.5 11.8 16.3 17.7 15.1 6.5 31.8 0.0 35.8 0.0 22.6 1.8 8.7 16.2 16.8 22.5 17.3 33.4 22.3 21.6 7.8 0.1 16.9 24.3 44.4 4.1 14.7 15.1 20.0 12.1 12.7 0.0 21.1 15.8 25.6 30.0 29.2 14.0 18.1 11.5 14.0 19.3 23.1 19.2 25.7 25.7 14.5 8.3 3.5 0.0 28.5 4.5 29.2 0.0 0.7 0.0 1.8 0.3 1.9 0.0 1.0 1.5 0.5 0.0 0.4 1.0 0.0 0.4 0.4 0.0 0.2 1.1 21.3 19.2 15.1 18.9 20.1 17.4 18.8 20.0 17.1 18.8 21.9 17.2 5.8 0.0 5.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 11.1 6.5 0.0 0.0 2.5 12.9 0.0 2.9 4.8 0.0 0.0 8.4 0.0 7.4 12.9 4.0 0.0 0.0 0.0 6.5 2.7 3.5 0.0 8.1 0.0 13.2 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 1.6 0.0 0.0 0.0 0.0 7.0 0.0 0.0 1.7 0.0 0.0 5.7 7.3 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 1.2 1.8 5.2 0.0 0.0 RTN2 "NSP2, NSPL1, SPG12" ENSG00000125744 "Reticulon 2" O75298 19 45485294-45497055 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "skeletal muscle: 509.8;tongue: 207.7" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 134.3;Extravillous trophoblasts: 145.7;Skeletal myocytes: 73.2;Syncytiotrophoblasts: 120.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 6.2;eosinophil: 2.6;plasmacytoid DC: 1.6" "Group enriched" "Detected in many" 10 "dendritic cells: 1.6;granulocytes: 6.2" "Cell line enhanced" "Detected in many" "RH-30: 44.3;RT4: 45.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034941, HPA034948" Approved Approved "Nuclear speckles" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nuclear speckles" "HPA034941: AB_10671358, HPA034948: AB_2674375" "unprognostic (3.08e-1)" "unprognostic (1.42e-1)" "unprognostic (6.68e-3)" "unprognostic (5.07e-3)" "unprognostic (1.76e-1)" "unprognostic (1.20e-1)" "unprognostic (2.31e-2)" "unprognostic (1.89e-2)" "unprognostic (3.09e-1)" "unprognostic (6.44e-2)" "unprognostic (5.10e-3)" "unprognostic (2.96e-2)" "prognostic unfavorable (5.58e-6)" "unprognostic (4.34e-1)" "unprognostic (3.23e-1)" "unprognostic (2.21e-1)" "unprognostic (2.03e-1)" 9.9 13.6 21.4 3.4 25.7 1.7 12.0 15.9 43.6 5.9 7.8 21.8 2.8 15.2 2.5 12.1 4.6 7.9 21.9 24.7 22.0 7.1 3.9 8.2 4.7 27.3 19.3 1.9 4.8 10.1 7.6 19.2 27.0 17.0 2.2 5.7 22.3 10.6 509.8 9.1 8.7 7.3 14.1 11.2 7.9 1.6 25.1 1.1 4.9 207.7 2.0 12.4 7.8 29.0 3.8 5.2 8.6 6.7 14.4 17.6 16.9 8.5 20.0 5.2 9.9 10.4 3.2 3.3 11.4 9.3 4.2 7.2 5.6 4.1 1.7 7.9 8.2 23.0 3.9 7.8 6.2 1.4 25.0 19.5 2.2 2.3 4.2 9.2 9.6 0.9 12.9 6.2 15.6 2.9 0.0 4.3 6.3 17.0 6.8 3.6 44.3 18.8 3.0 45.0 24.1 23.1 1.7 40.7 13.2 8.0 32.3 9.1 8.6 14.7 4.4 0.4 1.9 3.5 8.7 7.7 3.9 5.2 7.7 6.2 0.1 2.6 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.2 0.3 1.6 0.0 0.2 21.4 25.7 15.9 43.6 24.7 22.0 27.3 19.3 27.0 14.1 25.1 29.0 9.8 3.2 8.1 2.6 0.8 6.4 27.7 8.9 6.8 10.4 18.4 21.1 4.6 4.3 4.6 3.7 6.2 134.3 2.9 0.9 0.0 21.3 0.3 2.1 7.0 15.3 11.4 1.7 21.0 6.8 145.7 14.0 3.1 3.4 16.5 4.2 18.9 3.1 27.3 23.5 13.3 2.2 12.2 12.9 12.0 0.4 5.6 10.7 23.2 1.9 6.5 9.1 1.0 4.5 2.1 13.1 0.3 6.8 2.5 13.0 0.3 0.3 1.3 13.6 13.1 73.2 12.3 0.5 3.9 2.3 3.4 120.1 1.0 16.4 0.7 23.2 RUFY1 "FLJ22251, RABIP4, ZFYVE12" ENSG00000176783 "RUN and FYVE domain containing 1" Q96T51 5 179550554-179610012 "Plasma proteins, Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Macrophages: 137.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038804 Approved Supported "Nuclear speckles,Vesicles,Cytosol" NA NA 25000 "Cluster 41: Basophils - Cellular respiration" "Cluster 72: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 51: Myeloid cells - Hemostasis" "Vesicles, Cytosol" "Nuclear speckles" "HPA038804: AB_10673290" "unprognostic (3.17e-2)" "unprognostic (2.82e-1)" "unprognostic (9.24e-2)" "unprognostic (2.50e-1)" "unprognostic (1.26e-1)" "unprognostic (1.96e-1)" "unprognostic (2.04e-2)" "unprognostic (1.06e-1)" "unprognostic (1.74e-1)" "unprognostic (1.21e-1)" "unprognostic (9.74e-2)" "unprognostic (1.31e-1)" "unprognostic (2.73e-2)" "unprognostic (3.60e-1)" "unprognostic (2.08e-1)" "unprognostic (2.55e-1)" "unprognostic (5.85e-2)" 28.2 33.1 9.6 13.4 10.5 13.3 26.1 9.8 10.2 27.2 11.3 29.1 9.4 27.5 8.1 33.9 24.5 8.8 20.4 9.5 10.1 24.1 21.3 26.6 14.2 10.2 10.0 23.9 24.4 13.5 22.7 9.0 10.1 22.4 8.2 7.4 25.8 8.6 33.8 33.1 25.9 7.8 9.9 35.2 24.2 10.9 10.0 13.6 24.7 10.1 11.5 26.3 27.2 10.6 13.9 22.5 11.8 15.7 22.3 18.2 13.4 24.2 17.2 14.1 16.3 22.0 31.6 22.4 13.4 29.6 16.2 12.6 21.9 31.6 16.4 71.2 16.6 39.2 17.1 16.0 22.8 22.0 20.7 18.5 17.1 9.5 27.0 24.6 15.5 12.5 16.2 20.8 12.7 42.0 23.5 15.2 12.6 15.0 10.5 20.9 8.4 20.9 23.5 22.4 11.7 16.7 35.4 22.5 13.2 14.8 18.0 26.6 18.8 18.3 6.2 10.0 19.3 12.8 21.2 39.8 16.9 39.0 17.2 14.9 4.8 11.9 2.2 5.1 1.3 3.8 2.7 2.3 4.2 5.7 1.9 2.4 7.9 1.8 7.1 4.8 4.5 29.8 9.6 10.5 9.8 10.2 9.5 10.1 10.2 10.0 10.1 9.9 10.0 10.6 19.8 35.3 30.8 30.0 23.6 10.3 11.5 11.7 16.5 9.3 17.8 17.5 22.8 28.6 23.1 14.7 20.9 21.7 15.7 20.0 9.8 19.7 8.0 28.2 21.9 20.9 10.8 27.7 31.8 14.4 15.8 19.7 19.9 20.0 29.8 20.4 12.5 14.1 31.1 11.8 28.4 17.5 8.2 30.7 21.0 3.4 23.0 137.2 10.6 21.5 43.7 11.9 15.5 23.1 33.9 22.1 18.5 27.1 18.3 14.2 14.1 34.0 32.8 12.0 6.6 20.8 17.8 11.1 8.4 21.9 11.4 21.2 19.5 25.0 15.3 10.2 RUNDC1 DKFZp761H0421 ENSG00000198863 "RUN domain containing 1" Q96C34 17 42980565-42993690 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023726 Uncertain Approved "Nuclear speckles,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 11: Alveolar cells - Smell perception" "Nuclear speckles" Cytosol "HPA023726: AB_2184078" "unprognostic (4.24e-2)" "unprognostic (1.26e-1)" "unprognostic (9.39e-2)" "prognostic favorable (6.93e-5)" "unprognostic (9.78e-2)" "unprognostic (1.22e-1)" "unprognostic (6.40e-2)" "unprognostic (1.71e-1)" "unprognostic (2.59e-1)" "unprognostic (2.91e-2)" "unprognostic (3.84e-2)" "unprognostic (1.22e-1)" "unprognostic (1.53e-3)" "unprognostic (2.87e-3)" "unprognostic (1.25e-1)" "unprognostic (1.12e-2)" "unprognostic (4.77e-3)" 5.5 8.0 8.7 6.6 11.0 6.8 10.0 6.5 11.0 8.6 9.7 9.4 6.5 8.7 12.1 6.6 14.5 6.1 7.3 9.6 8.8 8.4 5.0 6.9 7.2 6.3 6.8 5.0 7.9 12.0 9.4 4.8 6.2 12.1 7.6 8.5 7.5 8.5 11.6 7.1 7.8 8.6 5.8 8.1 10.1 6.8 7.9 6.7 10.2 9.0 7.7 8.4 6.2 8.2 12.9 22.1 8.8 11.9 14.7 8.8 9.3 12.2 12.6 17.1 12.7 14.0 7.2 8.6 10.7 12.1 11.6 15.8 11.3 12.3 18.9 9.7 17.7 5.8 12.8 13.5 9.4 12.6 11.9 6.6 14.7 15.1 10.0 13.6 9.2 9.3 11.2 5.3 9.9 9.3 15.6 8.9 9.9 18.3 13.8 11.2 12.3 8.6 14.3 17.0 12.8 11.8 9.6 9.0 10.2 12.9 17.5 13.9 7.6 15.4 9.6 9.2 14.7 12.6 13.1 7.5 11.0 6.6 9.8 4.7 2.3 7.9 1.3 3.8 1.7 3.7 1.6 1.1 1.8 3.7 1.6 1.7 5.4 1.1 2.8 5.6 2.0 1.0 8.7 11.0 6.5 11.0 9.6 8.8 6.3 6.8 6.2 5.8 7.9 8.2 5.3 44.8 38.4 6.5 18.7 15.0 11.0 5.8 9.1 18.9 19.2 9.8 13.7 22.8 17.2 5.5 22.9 9.8 19.1 28.7 21.5 11.8 8.1 26.4 9.6 10.3 19.2 5.7 13.8 9.8 7.3 8.6 20.4 19.5 11.4 8.4 10.4 6.1 8.4 38.7 11.0 16.9 6.1 10.5 14.7 4.5 9.9 9.5 3.6 7.5 14.3 14.3 12.3 5.0 6.2 10.1 16.4 14.3 11.7 16.6 15.1 12.8 24.7 33.2 19.7 8.5 9.6 22.9 14.9 7.2 14.6 5.5 13.9 10.4 17.8 17.0 S100A11 S100C ENSG00000163191 "S100 calcium binding protein A11" P31949 1 152032506-152047907 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 4751.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 5473.4;Extravillous trophoblasts: 6093.0;Pancreatic endocrine cells: 6926.5;Urothelial cells: 6250.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 17820.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034320, HPA042745" Enhanced Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA 7900000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Nucleoplasm, Cytosol" "Nuclear speckles" "CAB034320: AB_2183487, HPA042745: AB_2678142" "unprognostic (1.85e-2)" "unprognostic (9.20e-2)" "unprognostic (1.99e-1)" "unprognostic (1.61e-1)" "unprognostic (3.12e-2)" "unprognostic (7.61e-2)" "prognostic unfavorable (3.64e-5)" "unprognostic (3.34e-2)" "unprognostic (8.48e-2)" "unprognostic (1.80e-2)" "unprognostic (1.28e-3)" "unprognostic (5.92e-2)" "prognostic unfavorable (3.24e-6)" "unprognostic (2.91e-1)" "unprognostic (2.75e-1)" "unprognostic (2.43e-3)" "unprognostic (8.86e-2)" 656.7 214.3 92.6 487.2 92.8 415.2 574.7 99.1 222.3 1070.5 106.8 303.0 181.6 297.7 675.4 4751.5 611.1 437.8 354.1 92.3 104.4 882.5 127.6 776.0 206.7 118.1 108.6 152.0 264.1 905.1 210.7 723.2 118.0 536.4 328.7 8.4 1247.1 544.1 91.0 894.7 239.5 468.3 110.2 713.7 482.6 68.9 124.1 303.5 325.3 150.9 959.9 1527.7 1771.1 126.8 1889.0 1483.7 70.5 542.1 1960.9 2451.3 1172.4 1796.3 2626.0 1439.7 1464.8 697.6 2066.0 2.5 1571.4 2355.4 1142.4 2595.4 73.7 3254.0 814.0 913.6 149.2 162.6 830.1 409.1 1511.3 149.6 1098.4 1867.2 3255.1 1577.8 1974.9 826.9 1116.1 0.3 340.9 352.1 2137.7 3058.8 19.8 694.0 513.9 4043.1 1491.9 2.5 757.1 1426.0 4361.1 3196.5 2.5 115.8 1367.7 1797.9 1255.3 1727.2 1378.9 1612.5 1584.8 757.0 533.1 1188.8 975.7 2.5 17.0 8.2 1713.0 490.9 915.2 7956.3 4682.6 7210.4 713.6 4560.1 939.4 354.9 1346.4 845.1 3020.5 252.7 391.5 437.0 17820.3 740.5 4871.8 1042.8 1269.9 5289.9 92.6 92.8 99.1 222.3 92.3 104.4 118.1 108.6 118.0 110.2 124.1 126.8 718.5 137.8 189.4 1.3 136.6 2210.3 3924.9 5473.4 1027.8 0.7 686.8 823.8 30.8 546.2 2673.9 2284.2 0.0 3257.0 384.0 421.7 1019.3 4344.5 277.6 1738.8 561.2 617.8 277.7 52.6 0.0 4330.2 6093.0 890.7 676.4 1503.0 437.6 251.1 372.6 11.6 3806.0 0.0 0.0 479.6 1485.2 1216.7 2054.0 634.0 320.9 1971.8 1243.3 15.9 2265.2 0.8 371.8 0.0 0.0 6926.5 690.2 258.4 153.8 4365.0 343.9 925.4 2674.2 2.4 210.4 536.2 1054.9 14.5 34.8 4207.9 2822.4 3753.1 470.4 334.8 500.2 6250.2 S100PBP "FLJ12903, S100PBPR" ENSG00000116497 "S100P binding protein" Q96BU1 1 32816767-32858875 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 78.8;Spermatocytes: 109.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027242, HPA027328" Approved Supported "Nuclear speckles" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nuclear speckles" "HPA027242: AB_2672174, HPA027328: AB_2672221" "unprognostic (4.29e-2)" "unprognostic (8.54e-2)" "unprognostic (3.54e-1)" "unprognostic (2.52e-3)" "unprognostic (2.44e-2)" "prognostic favorable (5.22e-5)" "prognostic unfavorable (1.26e-6)" "unprognostic (1.61e-1)" "unprognostic (2.52e-3)" "unprognostic (3.71e-1)" "unprognostic (6.79e-2)" "unprognostic (1.83e-2)" "prognostic unfavorable (9.03e-4)" "unprognostic (2.87e-1)" "unprognostic (1.06e-1)" "unprognostic (1.14e-1)" "unprognostic (1.48e-1)" 9.5 10.9 12.1 10.0 19.4 14.2 9.6 13.3 14.1 14.3 13.9 10.8 6.1 12.2 10.1 7.2 12.5 10.0 7.0 10.7 16.1 7.9 8.8 9.2 15.7 14.2 14.1 16.9 6.9 6.5 11.1 10.9 13.7 10.0 7.6 14.0 8.9 8.5 7.0 8.4 11.3 10.9 12.0 15.6 8.2 34.5 15.1 18.7 11.6 8.1 14.9 10.0 10.2 17.6 11.7 15.0 32.2 17.8 15.0 21.0 16.6 22.3 15.7 20.5 22.7 9.5 18.6 36.5 17.2 14.8 19.7 18.3 31.7 13.1 25.2 18.6 10.6 45.7 31.1 12.1 17.6 21.1 18.0 15.2 12.3 19.5 23.9 27.9 21.8 30.8 27.5 27.2 25.0 6.8 32.6 19.0 38.2 7.9 11.7 29.7 34.5 31.3 9.3 7.6 15.0 14.6 22.9 6.6 24.9 49.2 13.8 13.0 11.4 28.3 18.9 24.3 14.7 40.2 39.2 36.5 13.8 22.2 15.9 7.5 3.6 6.5 6.6 2.0 7.9 8.7 5.2 7.1 3.8 5.4 3.6 5.2 4.6 18.7 1.7 11.3 5.5 3.8 12.1 19.4 13.3 14.1 10.7 16.1 14.2 14.1 13.7 12.0 15.1 17.6 18.3 12.8 21.0 32.3 20.0 10.5 10.4 12.5 26.2 21.2 18.0 16.1 6.0 18.6 13.6 20.2 35.5 14.8 32.6 7.7 13.7 11.0 7.8 13.0 20.6 15.4 8.4 23.1 17.9 5.0 17.0 15.5 12.8 13.1 14.5 29.1 21.4 11.5 15.2 18.5 23.9 7.8 8.2 19.3 9.6 6.9 19.0 14.5 5.4 48.7 10.6 13.1 33.0 51.8 78.8 6.6 4.4 17.7 29.2 9.7 12.6 5.9 9.8 25.0 26.3 12.5 16.6 109.9 74.4 17.6 7.1 6.2 22.0 12.3 9.9 6.5 S1PR2 "AGR16, DFNB68, EDG5, Gpcr13, H218" ENSG00000267534 "Sphingosine-1-phosphate receptor 2" O95136 19 10221433-10231331 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 92.9;Early spermatids: 92.3;Late spermatids: 184.9;Syncytiotrophoblasts: 68.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 45.0" "Group enriched" "Detected in many" 8 "granulocytes: 45.0;T-cells: 12.4" "Cell line enhanced" "Detected in many" "BEWO: 29.4;Daudi: 54.1;U-266/70: 38.9;U-698: 57.3;WM-115: 38.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA014255, HPA014307" Approved Uncertain "Nuclear speckles,Golgi apparatus" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "Golgi apparatus" "Nuclear speckles" "HPA014255: , HPA014307: AB_1847989" "unprognostic (5.38e-3)" "unprognostic (1.83e-3)" "unprognostic (1.20e-1)" "unprognostic (1.26e-2)" "unprognostic (3.31e-2)" "unprognostic (1.05e-3)" "unprognostic (8.50e-2)" "unprognostic (8.71e-2)" "unprognostic (2.84e-1)" "unprognostic (1.70e-1)" "unprognostic (7.40e-3)" "unprognostic (1.47e-2)" "prognostic unfavorable (4.36e-10)" "unprognostic (4.91e-2)" "unprognostic (4.56e-2)" "unprognostic (3.11e-1)" "unprognostic (8.09e-2)" 7.7 2.5 1.9 6.4 1.8 1.2 5.5 1.7 1.8 10.4 1.9 4.8 1.8 8.3 2.7 3.3 8.4 6.2 6.6 1.6 2.0 3.1 5.6 13.7 10.9 2.8 1.9 5.6 2.9 2.5 3.0 18.5 2.2 6.9 2.4 1.2 4.1 2.3 0.8 5.4 4.8 4.2 2.0 1.9 4.3 13.2 2.1 1.4 3.4 1.3 10.9 8.3 7.0 2.9 3.0 0.4 3.4 6.9 18.2 22.2 29.4 4.4 8.9 1.9 4.1 1.9 1.7 54.1 5.1 8.2 2.3 1.7 1.2 2.1 1.3 5.5 2.7 1.2 1.2 1.3 6.1 1.4 1.1 12.2 1.1 3.8 1.3 5.3 0.2 2.6 1.3 11.1 1.3 2.5 0.6 2.5 3.4 0.9 1.7 3.8 1.4 2.0 1.6 2.5 2.4 4.7 2.5 1.5 3.8 2.6 1.2 1.3 0.4 6.9 2.2 15.9 1.3 38.9 19.6 57.3 2.6 2.7 38.6 45.0 2.8 0.6 7.2 2.4 8.9 0.3 9.2 7.0 2.6 0.5 3.7 3.8 0.7 3.6 1.0 0.4 12.4 2.0 1.9 1.8 1.7 1.8 1.6 2.0 2.8 1.9 2.2 2.0 2.1 2.9 2.0 0.0 1.1 0.3 2.0 0.0 4.6 0.0 1.2 0.6 8.3 4.6 0.6 2.8 0.6 1.8 2.1 92.9 5.4 0.0 0.0 3.6 92.3 8.6 21.5 2.0 2.4 0.0 0.3 3.3 18.1 17.7 0.0 18.1 0.0 2.0 3.9 7.6 13.2 0.0 0.9 0.5 0.0 3.1 0.0 184.9 22.1 7.2 0.0 0.0 4.0 7.1 3.1 6.6 0.5 2.7 0.3 13.2 2.6 4.9 0.0 0.9 0.0 0.5 13.1 2.0 4.6 1.5 1.2 2.0 0.0 68.4 4.2 1.1 0.2 4.1 SALL1 "Hsal1, TBS, ZNF794" ENSG00000103449 "Spalt like transcription factor 1" Q9NSC2 16 51135975-51151367 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" Deafness "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.0;kidney: 36.4;liver: 36.5" "Cell type enhanced" "Detected in some" "Astrocytes: 15.3;Cone photoreceptor cells: 25.0;Endometrial stromal cells: 17.5;Glandular and luminal cells: 14.3;Hepatocytes: 30.1;Microglial cells: 26.2;Oligodendrocytes: 47.6;Proximal tubular cells: 20.3" "Cancer enhanced" "Detected in many" "glioma: 19.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 29.5;BJ hTERT+: 25.3;NTERA-2: 48.0;RPTEC TERT1: 40.4;U-87 MG: 46.2" "Region enhanced" "Detected in all" "olfactory bulb: 52.6" "Low region specificity" "Detected in all" "HPA049829, HPA074673" Enhanced Approved "Nucleoplasm,Nucleoli,Nuclear speckles,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 21: Non-specific - Transcription" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nucleoli, Nuclear speckles, Cytosol" "HPA049829: AB_2680902, HPA074673: " "unprognostic (9.91e-2)" "unprognostic (9.42e-2)" "unprognostic (1.82e-6)" "prognostic favorable (1.28e-4)" "unprognostic (2.55e-1)" "unprognostic (1.17e-1)" "unprognostic (1.96e-2)" "unprognostic (4.41e-3)" "unprognostic (1.71e-2)" "unprognostic (2.88e-1)" "unprognostic (1.48e-1)" "unprognostic (3.96e-1)" "prognostic favorable (1.91e-7)" "unprognostic (1.86e-1)" "unprognostic (2.14e-1)" "unprognostic (3.03e-2)" "unprognostic (1.76e-1)" 0.3 0.0 18.0 0.6 29.2 0.1 0.3 29.7 21.3 19.6 2.1 2.6 1.0 17.4 0.0 0.3 11.0 0.4 0.8 17.9 21.7 36.4 36.5 0.0 0.0 41.0 32.2 4.5 1.0 6.5 6.5 3.9 36.6 0.8 2.6 4.6 0.2 1.6 0.0 0.2 1.3 8.4 31.1 0.0 2.5 1.7 26.6 0.1 23.7 0.2 0.0 2.8 7.2 40.2 0.0 1.7 29.5 0.2 0.8 0.6 0.0 10.0 25.3 0.6 1.4 0.0 0.0 0.0 11.2 14.1 8.8 0.0 18.6 0.0 0.9 0.0 11.3 0.0 0.0 18.5 0.7 0.0 8.1 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 48.0 0.0 0.0 3.8 1.9 0.0 40.4 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 46.2 0.0 10.0 0.2 0.6 0.5 0.1 0.4 0.1 0.2 0.2 0.1 0.4 0.2 0.1 0.1 0.3 0.0 0.3 0.4 0.2 0.3 18.0 29.2 29.7 21.3 17.9 21.7 41.0 32.2 36.6 31.1 26.6 40.2 0.0 0.0 0.0 15.3 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.1 1.4 10.0 0.0 9.2 25.0 0.0 0.0 0.0 11.7 0.5 0.7 8.9 17.5 0.9 0.0 2.7 0.2 0.0 0.0 1.6 0.0 14.3 0.0 0.0 0.7 30.1 0.1 0.0 8.2 0.0 0.0 1.0 0.3 0.1 0.0 0.4 0.0 26.2 0.0 0.5 0.0 5.0 47.6 0.0 0.0 0.0 0.0 0.0 0.0 20.3 0.0 1.0 0.0 0.0 0.5 0.2 2.3 0.0 0.1 0.0 0.3 0.6 0.0 0.1 SAP130 FLJ12761 ENSG00000136715 "Sin3A associated protein 130" Q9H0E3 2 127941217-128028120 "Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 47.3" "Cell type enhanced" "Detected in many" "Early spermatids: 71.5;Late spermatids: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034664 Supported "Nuclear speckles" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nuclear speckles" "HPA034664: AB_10603238" "unprognostic (2.17e-2)" "unprognostic (1.96e-2)" "unprognostic (1.85e-1)" "unprognostic (1.33e-1)" "unprognostic (5.45e-2)" "unprognostic (1.65e-1)" "prognostic unfavorable (7.89e-4)" "unprognostic (2.75e-1)" "unprognostic (1.30e-2)" "unprognostic (1.43e-1)" "unprognostic (3.92e-2)" "unprognostic (6.77e-2)" "unprognostic (3.75e-2)" "unprognostic (5.26e-2)" "unprognostic (4.41e-1)" "unprognostic (2.13e-1)" "unprognostic (1.13e-1)" 9.1 8.6 8.8 8.7 8.5 21.7 8.2 8.5 10.2 10.5 5.1 10.3 8.3 10.4 9.2 10.4 9.6 7.2 8.5 8.1 10.8 7.2 8.3 8.0 10.0 6.4 7.9 11.2 8.7 12.4 14.5 9.0 7.1 8.7 9.7 8.6 9.1 7.9 11.9 12.9 9.8 10.2 6.1 8.5 9.7 47.3 8.0 14.8 8.8 13.0 12.6 9.5 10.3 8.8 35.3 18.9 35.3 28.6 22.9 15.7 38.5 22.0 21.4 33.4 26.2 45.1 14.4 29.4 19.3 25.0 17.4 24.0 39.3 22.7 34.5 16.3 25.2 29.2 16.7 35.9 27.5 25.5 22.2 14.8 16.7 44.1 27.5 17.6 27.0 24.4 35.9 21.1 28.2 39.3 35.6 20.0 36.6 20.7 21.1 24.3 29.0 19.6 17.9 30.7 18.5 22.3 23.2 21.7 13.6 22.1 16.4 17.3 23.2 32.1 34.5 30.1 23.6 29.3 31.2 34.3 26.4 17.0 21.0 2.3 4.2 4.6 5.3 2.7 4.0 2.0 3.8 3.5 3.4 5.0 2.7 3.1 14.0 3.6 8.6 6.2 2.7 3.8 8.8 8.5 8.5 10.2 8.1 10.8 6.4 7.9 7.1 6.1 8.0 8.8 5.4 0.0 10.9 29.0 7.9 7.9 2.3 3.2 5.7 5.2 6.5 5.3 15.2 2.8 3.1 1.8 8.4 11.9 9.4 13.1 0.0 4.9 71.5 4.6 8.6 6.2 6.7 11.6 25.4 4.7 12.8 5.2 8.6 8.7 1.3 5.3 5.3 5.8 7.8 8.4 28.9 7.0 4.1 8.4 6.3 44.2 8.4 7.0 5.4 16.9 4.9 5.0 6.2 26.2 31.0 6.1 7.8 8.2 13.2 4.9 6.5 3.4 4.0 5.8 6.6 4.4 5.5 31.0 17.9 9.2 10.4 19.3 7.6 3.7 7.8 4.3 SARNP "CIP29, Hcc-1, THO1" ENSG00000205323 "SAP domain containing ribonucleoprotein" P82979 12 55752463-55817724 "Plasma proteins, Predicted intracellular proteins" "mRNA transport, Transcription, Transcription regulation, Translation regulation, Transport" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030902, HPA030903" Supported Supported "Nuclear speckles" NA NA 150000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nuclear speckles" "HPA030902: AB_10669872, HPA030903: AB_10964180" "unprognostic (1.83e-2)" "unprognostic (1.58e-2)" "unprognostic (2.22e-1)" "unprognostic (2.50e-1)" "unprognostic (3.01e-2)" "unprognostic (2.10e-1)" "unprognostic (2.36e-4)" "unprognostic (2.02e-2)" "unprognostic (4.29e-3)" "unprognostic (1.21e-2)" "unprognostic (5.03e-2)" "unprognostic (6.48e-2)" "unprognostic (2.31e-6)" "unprognostic (8.50e-2)" "unprognostic (1.31e-1)" "unprognostic (5.29e-3)" "unprognostic (1.19e-1)" 48.0 59.1 52.9 45.8 53.7 88.8 58.0 56.4 88.2 52.6 55.0 53.7 31.1 48.2 57.2 61.9 42.3 34.8 81.5 53.4 60.8 62.5 49.4 46.4 67.2 54.8 56.8 48.5 31.6 45.7 43.7 55.1 55.3 48.0 53.6 31.6 39.4 47.7 98.9 43.3 38.5 53.4 53.5 47.9 44.1 55.4 55.8 83.0 41.6 84.0 84.5 59.8 48.3 56.2 118.8 106.6 251.5 107.9 114.9 162.9 119.7 160.5 126.2 196.7 163.6 151.4 129.1 191.3 108.7 131.8 77.2 66.5 223.7 158.2 209.8 151.2 140.5 192.5 181.6 132.9 166.9 162.0 142.4 121.1 115.7 129.0 99.7 206.0 210.4 169.1 141.3 137.9 198.0 100.5 204.1 257.8 221.4 107.0 97.8 186.5 131.6 159.3 265.9 133.0 108.2 87.8 138.1 88.1 144.8 143.3 134.1 216.3 146.1 79.0 79.3 101.3 128.3 87.0 122.8 258.5 94.9 163.8 101.9 246.1 137.9 218.7 110.5 156.2 101.1 125.3 115.8 119.0 153.7 114.0 91.7 103.0 107.2 134.2 138.8 146.8 170.6 153.9 52.9 53.7 56.4 88.2 53.4 60.8 54.8 56.8 55.3 53.5 55.8 56.2 14.7 32.1 35.6 27.7 26.6 25.2 24.5 24.0 46.1 11.2 12.9 9.9 0.2 10.0 41.0 22.0 16.7 16.1 17.9 11.8 25.4 28.8 16.3 9.1 8.8 16.5 14.9 34.1 32.8 29.8 19.8 30.5 33.6 11.4 27.8 8.9 8.9 7.4 14.6 8.4 33.8 13.3 24.4 19.2 36.3 35.9 18.0 25.1 21.4 27.2 32.4 10.6 16.5 37.7 46.6 32.1 13.1 17.3 37.0 14.8 14.8 19.1 45.2 10.0 6.6 12.6 23.3 36.4 32.8 50.9 26.6 16.8 29.9 12.2 11.5 20.4 SART1 "Ara1, HAF, SNRNP110, Snu66" ENSG00000175467 "Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP" O43290 11 65961728-65980137 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Allergen, Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031188, HPA031189, HPA031190" Supported Enhanced "Nuclear speckles,Golgi apparatus" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "Golgi apparatus" "HPA031188: AB_10600092, HPA031189: AB_10601854, HPA031190: AB_10602289" "unprognostic (2.93e-2)" "unprognostic (1.13e-2)" "unprognostic (1.09e-2)" "unprognostic (1.76e-1)" "unprognostic (1.45e-1)" "unprognostic (6.99e-2)" "unprognostic (2.52e-3)" "unprognostic (8.15e-2)" "unprognostic (8.97e-2)" "unprognostic (2.10e-1)" "unprognostic (2.11e-2)" "unprognostic (3.05e-1)" "unprognostic (1.39e-1)" "unprognostic (1.04e-1)" "unprognostic (1.58e-1)" "unprognostic (1.62e-1)" "unprognostic (4.24e-2)" 24.6 18.3 15.5 18.3 16.8 41.6 23.1 15.4 17.4 29.2 14.7 26.0 15.6 29.1 8.0 22.7 25.6 8.6 23.2 14.9 16.1 20.4 21.8 22.9 20.3 16.6 16.2 29.2 25.8 11.7 21.4 14.0 15.9 21.7 7.7 8.0 22.2 14.4 38.1 32.0 24.3 10.9 14.6 32.7 24.8 23.5 15.7 20.9 23.5 13.0 13.3 26.2 24.6 17.9 50.4 60.8 27.2 36.8 26.1 20.7 40.8 37.5 27.2 43.8 28.6 44.2 34.3 56.9 42.4 33.8 52.9 48.7 34.6 35.6 22.0 45.8 33.5 65.6 43.6 41.4 39.0 57.4 52.7 26.2 26.4 40.8 36.3 17.4 27.6 42.3 42.2 39.8 25.6 92.6 74.0 83.5 45.7 27.3 55.9 80.8 39.0 60.7 18.4 33.7 30.5 43.0 35.6 37.2 45.5 12.6 41.7 47.0 40.6 54.5 53.0 53.9 54.1 59.6 49.4 48.3 45.0 28.8 47.0 1.4 2.8 8.1 4.3 3.5 3.6 3.9 4.8 4.4 3.6 3.5 3.5 3.9 4.1 2.8 2.0 3.2 5.4 1.8 15.5 16.8 15.4 17.4 14.9 16.1 16.6 16.2 15.9 14.6 15.7 17.9 17.5 6.4 9.1 7.8 27.8 22.7 24.0 12.2 17.6 19.2 12.2 9.1 9.4 21.5 11.3 16.5 10.4 34.1 27.2 30.5 5.9 23.7 9.0 14.2 16.3 19.8 12.5 32.8 5.1 29.3 31.9 17.6 21.9 16.8 32.4 21.8 21.0 15.6 29.4 16.8 4.8 26.5 16.2 22.5 23.6 8.7 37.0 22.9 17.8 6.5 35.7 23.8 34.0 7.1 7.8 26.3 20.1 33.1 31.2 20.5 28.3 18.5 17.5 26.0 32.9 27.6 34.9 26.7 29.7 18.3 21.7 45.3 28.4 15.5 27.5 18.2 SCAND1 "RAZ1, SDP1" ENSG00000171222 "SCAN domain containing 1" P57086 20 35953617-35959472 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 241.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA071335 Approved "Nuclear speckles" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear speckles" "HPA071335: " "unprognostic (3.88e-2)" "unprognostic (3.32e-1)" "unprognostic (1.42e-1)" "unprognostic (1.28e-3)" "unprognostic (2.94e-1)" "unprognostic (1.42e-1)" "unprognostic (1.83e-1)" "unprognostic (2.47e-1)" "unprognostic (1.18e-1)" "unprognostic (1.21e-2)" "unprognostic (4.09e-3)" "unprognostic (2.67e-2)" "unprognostic (1.56e-2)" "unprognostic (7.15e-3)" "unprognostic (3.53e-1)" "unprognostic (2.62e-1)" "unprognostic (3.48e-2)" 67.4 92.4 25.8 20.2 24.5 44.3 66.2 30.2 51.7 54.9 34.4 61.5 35.4 62.4 4.7 63.1 58.1 5.3 72.6 27.5 31.9 96.0 117.9 51.7 13.8 39.8 29.6 61.1 76.8 9.7 69.6 9.5 28.7 83.7 3.9 2.7 61.0 11.1 85.0 69.4 61.8 5.5 26.8 78.5 66.4 56.7 28.2 10.3 65.7 6.3 4.9 55.5 49.5 26.4 57.0 41.6 14.6 30.1 8.0 9.0 102.2 38.1 14.5 16.0 18.3 37.2 41.0 44.2 96.8 5.7 20.4 52.3 3.3 17.3 1.8 15.8 93.3 105.9 23.5 86.2 28.1 33.7 41.8 16.9 14.3 13.0 2.9 8.9 26.3 42.9 47.7 34.4 9.9 58.6 95.5 241.1 52.9 20.3 162.5 70.8 48.6 73.6 16.4 22.7 78.8 114.4 63.7 100.4 89.2 2.0 67.8 62.7 52.2 54.5 49.7 53.3 37.5 99.6 55.0 64.2 63.8 35.7 42.3 401.5 267.5 274.6 149.3 191.8 120.8 172.0 149.7 134.2 208.6 192.2 124.2 120.8 241.8 149.4 196.2 278.5 224.0 213.7 25.8 24.5 30.2 51.7 27.5 31.9 39.8 29.6 28.7 26.8 28.2 26.4 114.4 32.1 61.9 11.1 115.7 60.0 164.0 188.6 96.2 67.6 118.8 112.0 43.1 133.0 126.9 165.5 43.8 158.3 123.3 410.8 311.0 241.4 336.3 159.6 98.0 123.0 281.3 131.1 5.5 337.3 159.7 105.6 159.0 127.2 69.7 122.4 185.6 292.4 205.9 52.2 7.1 269.8 201.4 197.4 91.5 79.8 118.7 134.5 104.9 6.5 202.2 154.6 148.3 7.1 14.3 283.0 418.6 100.1 137.2 162.4 378.8 596.9 149.1 88.0 111.7 83.9 117.4 96.0 38.2 110.3 75.0 163.8 131.0 153.8 200.8 217.3 SCAPER "Zfp291, ZNF291" ENSG00000140386 "S-phase cyclin A associated protein in the ER" Q9BY12 15 76347904-76905444 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Mental retardation, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 55.4" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 252.3;Oligodendrocytes: 251.5;Rod photoreceptor cells: 710.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046253, HPA048077" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA No "Cluster 11: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 16: U-266 - Nucleosome" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Nuclear speckles" Cytosol "HPA046253: AB_2679600, HPA048077: " "unprognostic (3.67e-1)" "unprognostic (8.60e-2)" "unprognostic (6.08e-2)" "unprognostic (8.37e-2)" "unprognostic (1.48e-1)" "unprognostic (1.63e-1)" "unprognostic (1.37e-1)" "unprognostic (2.76e-2)" "unprognostic (4.94e-2)" "unprognostic (3.74e-2)" "unprognostic (5.40e-2)" "unprognostic (1.02e-1)" "prognostic favorable (2.69e-9)" "unprognostic (2.14e-1)" "unprognostic (3.79e-1)" "unprognostic (1.86e-1)" "unprognostic (2.89e-3)" 5.5 7.9 9.7 4.0 12.2 7.4 6.9 18.2 10.4 6.2 6.5 6.0 6.5 7.4 7.7 8.9 6.4 5.3 13.8 9.0 12.8 9.0 7.5 6.3 4.7 11.5 10.5 12.1 8.3 14.5 8.2 6.5 11.3 7.0 4.4 55.4 7.9 6.2 13.6 6.9 6.3 6.3 9.2 5.9 6.1 21.0 10.7 8.6 12.2 12.0 6.0 5.0 6.5 16.3 6.3 5.8 7.8 4.5 3.9 7.0 6.5 8.3 5.9 3.8 5.4 6.1 5.0 6.3 7.2 2.8 10.0 6.7 18.5 3.5 5.7 14.7 9.1 3.3 6.8 3.0 4.9 9.0 7.6 5.9 6.0 4.5 7.3 8.2 5.2 12.6 4.8 17.5 6.6 2.6 8.8 2.7 2.3 5.5 3.3 7.9 12.4 2.2 3.5 6.3 18.4 8.9 11.2 3.9 9.0 9.4 5.8 7.3 6.3 8.7 8.1 4.1 7.4 10.5 23.7 8.9 5.1 11.1 5.9 40.8 6.3 17.4 11.4 3.5 13.1 16.3 11.5 10.3 3.6 17.0 18.8 12.1 10.7 17.1 4.2 9.3 9.7 4.2 9.7 12.2 18.2 10.4 9.0 12.8 11.5 10.5 11.3 9.2 10.7 16.3 28.5 99.3 61.5 190.7 33.2 20.6 28.9 10.6 18.8 91.5 13.9 15.5 191.3 12.8 27.4 12.9 252.3 33.8 26.6 17.1 1.9 14.6 59.1 10.6 13.8 23.5 16.2 1.7 151.5 6.0 11.8 22.1 17.3 18.4 22.1 41.9 21.8 9.3 14.3 77.4 201.8 9.0 6.1 13.6 11.3 24.9 20.5 14.4 10.6 135.9 12.8 51.3 34.0 203.1 251.5 6.5 11.4 19.2 28.6 15.9 72.6 7.8 12.3 710.6 19.7 39.1 23.5 143.9 68.9 15.1 18.8 52.0 30.5 26.7 13.4 19.7 SDE2 "C1orf55, FLJ35382" ENSG00000143751 "SDE2 telomere maintenance homolog" Q6IQ49 1 225982702-225999343 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA replication, Mitosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 72.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028467, HPA031255, HPA031256" Approved Supported "Nuclear speckles,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 41: Macrophages - Immune response" "Nuclear speckles" "Golgi apparatus, Plasma membrane, Cytosol" "HPA028467: AB_10599192, HPA031255: AB_10601462, HPA031256: AB_10603568" "unprognostic (9.69e-2)" "unprognostic (2.69e-2)" "unprognostic (1.10e-1)" "unprognostic (2.36e-2)" "unprognostic (2.12e-1)" "unprognostic (3.10e-1)" "unprognostic (9.59e-2)" "unprognostic (2.68e-1)" "unprognostic (3.63e-2)" "unprognostic (1.84e-2)" "unprognostic (3.34e-2)" "unprognostic (9.01e-2)" "unprognostic (1.41e-3)" "unprognostic (3.90e-2)" "unprognostic (3.51e-1)" "unprognostic (3.98e-2)" "unprognostic (3.84e-2)" 17.4 8.5 5.5 11.3 7.0 32.9 11.8 6.4 6.6 9.0 4.8 8.3 9.0 11.8 7.8 9.6 7.4 10.5 7.7 4.9 6.0 9.2 14.6 9.2 12.4 6.9 6.6 10.2 9.6 11.1 4.4 11.8 6.6 9.8 9.1 5.1 6.7 7.3 12.7 10.8 9.0 9.8 6.6 10.4 7.7 8.3 6.1 22.8 12.5 9.6 10.6 11.6 7.8 8.4 13.1 9.3 14.9 15.9 10.2 11.3 18.5 13.7 12.9 18.4 14.0 13.7 14.7 19.2 20.9 11.6 7.2 16.5 18.9 11.9 22.2 14.7 15.3 21.1 7.9 12.7 18.6 21.0 24.6 12.5 16.9 19.6 24.6 10.3 12.8 22.6 39.3 22.6 13.7 3.8 29.5 16.6 20.8 20.2 9.8 24.4 19.1 24.9 11.1 9.2 13.3 22.0 15.6 16.9 26.3 11.9 16.6 25.4 12.7 15.6 11.0 20.3 30.4 13.4 10.3 23.4 16.1 12.9 31.5 21.8 6.3 5.9 8.0 6.4 10.8 8.0 8.1 7.8 7.1 7.0 8.1 7.7 18.5 13.5 7.9 8.1 6.7 6.9 5.5 7.0 6.4 6.6 4.9 6.0 6.9 6.6 6.6 6.6 6.1 8.4 36.0 28.9 22.6 4.2 39.9 43.6 17.2 11.2 29.0 6.2 19.8 13.6 9.4 2.8 20.1 9.2 0.0 9.6 29.3 14.3 15.6 6.5 72.8 24.8 15.1 24.8 17.4 56.2 4.7 7.1 10.2 17.8 13.3 35.9 35.5 9.7 12.8 20.6 11.1 15.2 5.0 10.8 16.2 16.4 28.8 20.4 9.9 27.0 19.6 1.9 7.4 12.6 10.3 4.5 8.6 9.7 9.4 6.4 26.6 14.2 9.5 12.7 12.7 8.9 6.6 28.8 23.9 23.9 14.4 26.5 59.1 14.2 23.2 21.0 9.9 18.2 SERPINB13 "headpin, HUR7, hurpin, PI13" ENSG00000197641 "Serpin family B member 13" Q9UIV8 18 63586989-63604639 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 56.6;esophagus: 180.4;vagina: 135.0" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 58.8;Club cells: 54.8;Squamous epithelial cells: 148.6" "Group enriched" "Detected in many" 5 "cervical cancer: 45.9;head and neck cancer: 27.6;lung cancer: 12.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 129 "HaCaT: 198.9;hTCEpi: 74.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA052630, HPA057129" Enhanced Approved "Nuclear speckles,Cytosol" NA NA 210000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Nuclear speckles, Cytosol" "HPA052630: AB_2681891, HPA057129: AB_2683347" "unprognostic (3.49e-2)" "unprognostic (3.73e-1)" "unprognostic (1.11e-1)" "unprognostic (7.27e-2)" "unprognostic (2.28e-1)" "unprognostic (4.29e-2)" "unprognostic (2.81e-1)" "unprognostic (6.04e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.1 56.6 0.0 0.0 0.0 0.0 0.0 180.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 35.7 0.0 0.0 13.6 0.0 0.0 0.0 0.0 0.1 0.0 0.2 1.2 0.0 0.0 22.9 3.3 135.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 198.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 1.7 1.9 58.8 13.1 0.0 0.0 0.1 0.1 0.0 54.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.8 0.0 0.0 8.5 0.0 0.0 0.0 1.0 0.0 0.0 148.6 1.3 0.5 0.0 0.0 0.0 19.9 SETD1A "KIAA0339, KMT2F, Set1" ENSG00000099381 "SET domain containing 1A, histone lysine methyltransferase" O15047 16 30957754-30984664 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Methyltransferase, RNA-binding, Transferase" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020646, HPA058376" Enhanced Supported "Nuclear speckles" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nuclear speckles" "HPA020646: AB_1856752, HPA058376: AB_2683695" "unprognostic (8.62e-2)" "unprognostic (1.93e-2)" "unprognostic (3.96e-2)" "unprognostic (1.53e-1)" "unprognostic (1.85e-1)" "unprognostic (1.40e-2)" "prognostic unfavorable (8.47e-4)" "unprognostic (5.01e-2)" "unprognostic (1.54e-1)" "unprognostic (3.18e-1)" "unprognostic (5.77e-2)" "unprognostic (1.72e-1)" "unprognostic (1.55e-1)" "unprognostic (1.27e-1)" "unprognostic (2.12e-1)" "unprognostic (1.70e-2)" "unprognostic (1.94e-1)" 10.2 10.0 6.0 7.3 5.5 20.1 10.0 8.4 8.3 11.0 3.0 13.0 6.6 13.0 2.8 9.0 10.5 4.1 8.5 5.5 5.5 8.4 10.4 8.2 8.6 5.6 5.4 12.4 10.6 8.0 11.9 5.0 5.4 10.2 3.3 3.1 9.3 6.1 15.1 12.3 10.5 6.3 4.1 11.8 10.0 20.8 6.0 10.0 11.8 7.1 5.1 10.2 9.3 6.9 13.1 24.4 15.9 19.4 8.7 6.3 18.0 13.6 10.6 11.9 10.1 20.2 12.8 34.2 15.2 13.0 12.0 16.4 15.0 14.6 9.3 18.5 56.1 16.0 47.1 23.2 8.9 26.6 26.2 11.0 11.3 17.1 10.8 9.2 9.3 19.5 32.3 19.0 6.4 27.2 32.3 27.7 23.4 9.0 15.4 48.7 15.9 21.9 7.6 13.9 17.6 18.1 18.7 15.1 10.8 8.7 16.2 22.1 12.8 17.7 17.1 11.6 14.9 28.0 36.2 32.4 14.3 22.9 13.5 0.0 0.1 0.6 0.2 0.3 0.3 0.0 0.2 0.2 0.1 0.5 0.1 0.2 0.0 0.2 0.1 0.6 0.1 0.2 6.0 5.5 8.4 8.3 5.5 5.5 5.6 5.4 5.4 4.1 6.0 6.9 7.8 3.2 9.2 9.1 8.8 15.7 5.1 3.8 15.4 8.1 9.5 8.3 3.9 5.7 4.0 7.3 6.2 4.6 11.4 6.8 0.0 4.2 3.1 6.1 8.2 9.9 10.3 6.7 6.4 4.2 3.7 7.8 6.1 8.6 3.8 9.5 7.5 9.1 6.5 13.5 6.1 7.9 2.0 4.7 7.1 2.9 9.9 5.5 8.8 6.5 4.7 4.8 7.2 2.5 5.7 5.4 4.8 11.7 7.9 8.3 5.1 2.8 4.0 5.2 6.6 10.8 7.8 17.5 23.3 15.7 12.9 2.9 8.6 10.3 6.9 4.8 SETD2 "FLJ23184, HIF-1, HYPB, KIAA1732, KMT3A" ENSG00000181555 "SET domain containing 2, histone lysine methyltransferase" Q9BYW2 3 47016429-47164113 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Differentiation, DNA damage, DNA repair, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Methyltransferase, Transferase" "Autism spectrum disorder, Cancer-related genes, Disease variant, Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042451 Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" Cytosol "HPA042451: AB_10806239" "unprognostic (2.78e-1)" "unprognostic (1.01e-1)" "unprognostic (6.08e-2)" "unprognostic (1.01e-1)" "unprognostic (3.37e-2)" "unprognostic (1.37e-2)" "unprognostic (1.40e-2)" "unprognostic (1.01e-2)" "prognostic unfavorable (8.19e-4)" "unprognostic (6.19e-2)" "unprognostic (2.45e-1)" "unprognostic (7.84e-2)" "prognostic favorable (7.99e-6)" "unprognostic (1.03e-1)" "unprognostic (1.91e-1)" "unprognostic (8.79e-2)" "unprognostic (5.43e-2)" 9.9 6.5 8.2 10.7 10.5 23.8 10.3 24.1 8.3 12.6 10.8 9.7 9.1 13.3 6.1 9.8 11.0 8.5 7.2 6.2 6.7 10.8 10.0 9.4 13.5 8.3 8.5 15.3 13.3 16.2 2.2 11.4 8.4 10.2 11.0 10.6 9.6 9.7 11.1 9.0 10.3 11.9 8.1 11.4 10.7 13.1 7.9 19.2 15.5 14.5 13.3 9.8 4.0 12.8 21.1 13.2 25.4 14.5 15.3 18.9 11.3 17.9 17.0 20.8 19.9 15.4 13.8 43.5 11.6 25.5 20.0 12.4 29.5 17.6 27.6 27.5 12.2 47.3 24.8 12.4 11.7 34.1 26.5 15.2 17.3 20.7 24.6 15.3 20.1 22.8 29.9 16.6 17.8 9.5 26.7 8.5 20.6 9.4 15.4 17.5 25.6 23.2 12.4 26.6 10.9 17.6 29.5 11.8 12.0 17.2 12.9 27.5 26.7 24.6 18.1 21.5 29.9 22.0 25.4 43.7 14.2 19.6 14.6 1.3 1.2 2.9 2.0 1.1 1.1 2.2 1.2 1.6 1.4 2.5 1.7 1.6 3.3 3.6 1.1 1.5 0.6 0.6 8.2 10.5 24.1 8.3 6.2 6.7 8.3 8.5 8.4 8.1 7.9 12.8 50.5 48.1 58.8 115.9 58.3 33.3 22.6 15.6 54.1 40.5 31.0 29.1 67.2 27.1 53.2 11.0 41.7 20.3 58.2 32.6 11.7 20.9 26.1 62.8 63.0 41.2 22.1 38.9 131.4 22.4 12.7 39.2 56.6 66.2 58.8 68.9 23.6 29.8 16.8 26.9 129.4 28.2 14.2 28.8 26.5 35.1 30.4 42.7 17.8 148.9 37.9 22.7 43.3 113.1 143.2 23.7 22.3 33.1 54.0 31.2 24.6 11.5 49.7 39.9 13.1 56.1 42.6 71.0 29.3 60.2 35.7 18.5 65.3 57.1 29.5 34.7 SETD4 "C21orf18, C21orf27" ENSG00000185917 "SET domain containing 4" Q9NVD3 21 36034541-36079389 "Predicted intracellular proteins" "Inflammatory response" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 54.3;Spermatocytes: 63.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA024073, HPA035405" Approved Approved "Nuclear speckles" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 27: Brain & Skin - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" "HPA024073: AB_1856755, HPA035405: AB_2674612" "unprognostic (4.23e-1)" "unprognostic (5.67e-2)" "unprognostic (6.98e-2)" "unprognostic (5.73e-2)" "unprognostic (1.98e-1)" "unprognostic (8.05e-3)" "unprognostic (7.86e-2)" "unprognostic (2.13e-3)" "unprognostic (2.17e-2)" "unprognostic (5.81e-2)" "unprognostic (1.33e-1)" "unprognostic (4.60e-3)" "unprognostic (1.15e-3)" "unprognostic (1.99e-1)" "unprognostic (8.09e-3)" "unprognostic (3.30e-2)" "unprognostic (1.28e-2)" 8.8 9.3 9.1 6.9 9.9 8.4 9.1 9.4 10.4 10.2 15.8 9.5 11.4 9.7 11.1 10.9 10.8 7.8 10.1 9.4 10.5 9.7 7.2 8.4 8.7 9.0 8.3 9.7 7.8 10.0 8.9 9.0 9.5 10.2 9.4 9.6 10.0 7.9 9.8 13.6 9.3 10.9 8.4 8.5 9.9 23.1 9.9 11.1 10.1 8.8 10.9 9.9 10.7 12.1 13.3 9.2 13.6 17.3 6.5 7.9 21.9 17.1 15.0 17.3 11.5 19.2 11.5 7.1 11.9 7.8 13.3 9.7 10.3 10.2 15.0 12.7 12.4 19.2 16.2 12.6 15.9 18.3 10.7 8.3 17.2 11.7 15.0 9.8 13.1 9.6 25.5 12.7 10.7 14.3 12.3 26.3 28.2 11.3 11.6 18.2 10.0 17.3 18.9 9.3 11.2 17.9 17.4 18.5 17.6 11.7 16.3 15.2 11.0 15.0 5.6 9.4 15.9 20.3 31.7 11.2 15.6 24.9 13.2 5.9 12.5 11.3 8.1 10.0 9.0 16.2 10.3 8.8 14.6 13.2 7.3 8.6 9.5 11.0 10.2 15.6 13.0 7.7 9.1 9.9 9.4 10.4 9.4 10.5 9.0 8.3 9.5 8.4 9.9 12.1 9.7 9.6 7.0 11.1 10.8 12.1 11.3 18.6 15.4 13.3 9.0 8.9 9.2 7.2 13.7 9.2 31.3 16.3 13.4 7.9 5.9 12.7 54.3 16.8 10.9 9.3 3.6 7.2 17.4 8.2 9.6 10.4 8.6 8.7 11.4 17.0 7.5 5.5 10.6 3.3 19.2 13.4 26.4 6.9 5.1 10.4 9.6 5.0 10.6 4.7 8.0 7.6 14.4 19.6 19.8 10.0 9.4 10.1 6.2 11.2 20.7 10.3 23.8 21.0 6.6 8.9 9.0 63.1 20.8 13.2 9.1 9.4 8.1 14.8 11.3 11.3 SF3A1 "Prp21, PRPF21, SAP114, SF3a120" ENSG00000099995 "Splicing factor 3a subunit 1" Q15459 22 30331988-30356919 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000690, HPA030083" Enhanced Enhanced "Nucleoplasm,Nuclear speckles" NA NA 87000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Nuclear speckles" "HPA000690: AB_1079933, HPA030083: AB_10602183" "unprognostic (8.61e-2)" "unprognostic (1.60e-1)" "unprognostic (3.21e-2)" "unprognostic (7.54e-2)" "unprognostic (5.06e-3)" "unprognostic (1.79e-1)" "unprognostic (5.54e-3)" "unprognostic (3.30e-1)" "unprognostic (3.83e-1)" "unprognostic (2.59e-1)" "unprognostic (2.58e-1)" "unprognostic (3.26e-1)" "prognostic favorable (1.16e-4)" "unprognostic (2.25e-1)" "unprognostic (1.00e-1)" "unprognostic (6.97e-2)" "unprognostic (1.13e-1)" 36.2 29.7 14.1 45.4 19.0 58.0 35.0 19.2 20.5 33.4 12.6 31.2 29.8 36.3 20.5 34.0 31.8 21.3 28.0 15.3 12.7 25.5 27.5 31.0 44.1 16.6 14.8 46.4 32.9 42.8 24.3 29.0 14.1 29.4 27.0 36.4 33.3 28.1 51.1 40.5 32.8 29.9 13.3 42.0 31.8 49.2 15.9 42.6 31.6 25.8 41.4 33.2 32.8 20.7 86.2 58.9 79.4 77.6 46.4 41.3 94.8 66.5 42.7 71.4 52.8 78.8 55.9 106.4 44.6 47.7 55.9 80.4 101.6 70.8 77.7 97.4 88.4 99.3 69.1 65.3 41.8 202.1 106.3 41.7 49.6 89.5 72.4 40.1 52.1 56.6 112.5 108.0 52.8 49.1 99.4 46.2 132.0 65.7 48.4 139.5 99.4 86.8 40.9 93.6 82.2 74.9 84.4 50.8 78.4 52.5 62.3 65.4 72.9 90.2 80.0 65.1 124.4 83.2 108.2 106.9 69.4 73.8 95.0 6.7 8.9 14.1 10.9 9.8 11.2 10.4 11.0 11.8 9.2 11.0 12.0 11.2 14.1 11.0 13.0 5.6 14.5 8.0 14.1 19.0 19.2 20.5 15.3 12.7 16.6 14.8 14.1 13.3 15.9 20.7 32.4 57.7 66.5 12.1 60.8 26.1 25.4 19.0 37.0 17.6 25.7 24.4 27.6 34.3 30.5 31.3 16.7 32.5 49.2 30.8 17.6 25.7 106.1 30.5 23.1 32.6 25.1 36.1 7.5 29.4 39.7 29.1 35.2 29.1 52.6 76.3 28.2 28.4 40.6 26.9 9.4 30.7 16.2 37.2 28.3 116.8 35.1 39.8 17.8 5.6 58.5 27.1 46.4 6.0 7.1 28.8 31.3 37.6 45.5 26.4 31.8 17.0 39.4 20.3 46.0 29.0 27.3 64.3 41.6 37.8 27.3 34.6 55.8 26.7 33.9 25.8 SF3A3 "PRP9, PRPF9, SAP61, SF3a60" ENSG00000183431 "Splicing factor 3a subunit 3" Q12874 1 37956975-37990075 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032054, HPA032055" Supported Supported "Nucleoplasm,Nuclear speckles" NA NA 57000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" Nucleoplasm "HPA032054: AB_10602184, HPA032055: AB_2674130" "unprognostic (1.56e-1)" "unprognostic (1.21e-1)" "unprognostic (7.08e-3)" "unprognostic (6.19e-3)" "unprognostic (1.06e-1)" "unprognostic (5.68e-2)" "prognostic unfavorable (2.11e-8)" "unprognostic (1.34e-1)" "unprognostic (2.74e-2)" "unprognostic (5.74e-3)" "unprognostic (9.18e-2)" "unprognostic (4.79e-1)" "unprognostic (1.23e-2)" "unprognostic (2.52e-3)" "unprognostic (8.39e-2)" "unprognostic (2.24e-1)" "unprognostic (3.68e-2)" 24.6 23.4 22.3 29.2 22.6 57.9 31.7 24.1 29.0 25.6 23.2 25.1 20.4 30.5 33.7 23.3 27.5 19.1 18.6 22.0 22.8 26.0 27.4 22.9 39.0 22.6 22.6 32.1 20.3 30.6 16.2 25.4 22.9 24.9 30.0 29.9 23.5 28.8 49.6 29.2 21.4 31.7 22.3 27.4 20.0 27.5 23.4 43.4 26.9 27.4 44.6 28.1 18.8 24.0 84.4 57.0 108.1 90.8 63.3 57.7 129.6 82.2 69.1 131.9 106.4 97.2 84.4 165.8 68.1 73.6 51.6 71.5 136.7 108.6 162.3 74.9 125.7 206.3 92.3 86.7 57.9 261.1 93.5 54.9 75.4 135.5 88.4 58.6 89.9 112.6 176.1 60.0 95.2 53.2 131.4 123.0 268.0 80.4 89.9 156.8 197.0 110.7 59.4 83.5 95.8 69.4 104.2 47.1 83.9 95.1 54.0 90.3 82.0 70.3 79.6 64.9 157.2 57.6 89.5 166.4 65.6 215.6 92.1 37.2 41.3 28.4 56.1 53.3 55.0 54.9 65.3 56.7 53.1 68.9 69.4 58.9 4.6 56.2 61.8 32.5 75.5 61.7 22.3 22.6 24.1 29.0 22.0 22.8 22.6 22.6 22.9 22.3 23.4 24.0 37.3 51.3 35.0 11.4 42.2 47.3 38.6 46.6 55.2 37.0 21.3 27.7 22.7 20.0 42.3 22.0 22.9 59.1 40.7 12.1 39.2 44.4 37.9 23.7 42.4 35.8 15.6 53.6 15.7 38.1 69.2 41.6 15.3 25.3 42.4 43.0 25.0 23.6 51.5 26.9 14.9 23.9 34.6 28.0 39.8 14.0 39.7 34.2 39.2 6.5 82.9 45.6 44.3 11.1 11.5 35.4 13.1 54.2 41.5 28.5 19.0 29.2 27.8 38.6 39.5 47.2 68.3 120.8 55.2 36.5 41.8 33.0 42.9 53.5 31.4 24.0 SF3B1 "Hsh155, Prp10, PRPF10, SAP155, SF3b155" ENSG00000115524 "Splicing factor 3b subunit 1" O75533 2 197388515-197435079 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing, mRNA splicing" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050275 Approved Enhanced "Nuclear speckles" NA NA 94000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 50: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "HPA050275: AB_2681071" "unprognostic (6.86e-2)" "unprognostic (2.78e-1)" "unprognostic (2.14e-1)" "unprognostic (3.51e-1)" "unprognostic (4.42e-2)" "unprognostic (1.25e-3)" "unprognostic (2.44e-3)" "unprognostic (3.31e-3)" "unprognostic (1.25e-2)" "unprognostic (2.20e-1)" "unprognostic (6.79e-2)" "unprognostic (1.78e-2)" "unprognostic (2.57e-2)" "unprognostic (9.15e-2)" "unprognostic (1.16e-1)" "unprognostic (1.79e-1)" "unprognostic (3.41e-2)" 183.8 173.9 101.7 132.7 112.4 304.8 180.7 120.5 126.1 222.8 136.8 170.9 110.4 195.8 200.0 136.8 183.8 123.2 135.7 98.2 100.8 135.4 168.5 162.8 203.0 105.7 101.9 226.5 200.7 154.9 147.8 165.3 111.0 163.2 147.3 138.4 180.4 133.2 172.4 156.5 231.6 116.5 107.5 287.8 169.2 91.4 104.9 221.9 167.8 144.8 199.3 154.4 167.1 135.8 134.9 105.4 288.6 155.9 222.8 219.2 237.8 172.6 196.7 163.2 205.9 233.0 147.2 247.5 116.6 193.1 165.8 133.7 273.4 151.2 271.8 196.5 154.8 237.5 257.4 294.3 155.4 270.1 198.6 232.1 163.0 175.9 209.3 278.6 205.9 171.0 210.2 174.0 192.3 134.2 251.1 285.6 231.4 167.5 163.8 234.4 197.9 182.9 245.8 286.4 154.2 186.7 174.7 118.2 139.2 345.1 115.2 242.5 186.8 126.9 109.4 123.3 145.8 168.7 238.8 342.0 123.7 174.8 146.5 49.8 50.4 57.5 54.5 51.7 55.4 46.1 46.2 50.9 60.5 44.1 48.7 49.2 60.8 56.7 52.5 37.5 71.3 56.2 101.7 112.4 120.5 126.1 98.2 100.8 105.7 101.9 111.0 107.5 104.9 135.8 175.6 179.5 222.9 92.4 187.4 119.0 172.0 127.1 125.7 103.4 96.4 83.3 129.2 72.9 194.0 92.0 73.0 116.8 224.1 90.1 56.7 104.8 9.2 123.9 191.0 143.1 110.5 109.0 55.5 94.8 102.3 151.6 132.0 179.0 246.9 171.1 107.1 74.4 100.6 94.2 59.7 108.1 89.5 124.7 144.1 20.6 120.2 166.1 76.5 75.9 163.9 111.1 116.4 87.0 121.1 112.0 68.3 104.6 195.6 103.8 84.2 70.5 221.5 98.5 118.3 159.5 227.9 104.6 100.5 94.3 118.8 142.7 216.2 119.4 91.4 156.1 SF3B2 "Cus1, SAP145, SF3b1, SF3b145" ENSG00000087365 "Splicing factor 3b subunit 2" Q13435 11 66050729-66069308 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045028 Supported Enhanced "Nuclear speckles" NA NA 130000 "Cluster 5: Granulocytes - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" "HPA045028: AB_10965174" "unprognostic (1.48e-1)" "unprognostic (1.51e-1)" "unprognostic (6.45e-2)" "unprognostic (3.29e-1)" "unprognostic (9.86e-2)" "unprognostic (7.10e-2)" "prognostic unfavorable (6.43e-5)" "unprognostic (8.43e-2)" "unprognostic (4.69e-1)" "unprognostic (2.79e-1)" "unprognostic (3.15e-2)" "unprognostic (1.44e-1)" "prognostic favorable (3.51e-5)" "unprognostic (4.03e-2)" "unprognostic (3.56e-1)" "unprognostic (5.14e-2)" "unprognostic (2.60e-2)" 116.0 96.0 117.5 80.4 127.1 144.6 109.0 119.4 139.5 123.3 125.1 97.4 70.7 111.6 95.5 96.6 112.3 55.2 94.7 117.9 120.4 107.1 112.0 104.3 99.0 124.2 118.9 136.1 137.4 88.9 137.2 80.6 121.3 99.2 77.0 96.5 91.3 73.8 108.1 116.9 98.5 80.0 121.4 113.9 102.9 145.2 124.0 109.4 115.2 54.6 114.0 108.3 104.7 136.9 226.9 177.3 189.0 178.9 184.3 163.5 153.1 168.4 210.5 234.9 176.8 149.8 188.9 212.5 185.7 186.7 249.5 202.9 263.2 177.8 208.8 170.2 143.5 223.3 164.2 245.5 187.8 229.7 171.5 137.9 174.0 242.5 287.8 171.3 172.7 180.5 215.2 348.7 191.4 309.8 257.5 343.2 196.1 166.2 163.9 235.6 162.9 299.0 192.3 186.0 147.8 218.0 165.9 175.9 257.0 136.3 217.2 147.1 156.7 206.9 178.0 229.0 194.3 267.5 337.0 270.8 229.6 151.6 191.9 152.1 96.2 167.9 135.3 117.2 131.1 106.8 120.3 128.2 98.5 110.2 116.7 116.8 130.2 116.3 160.1 78.8 131.8 147.5 117.5 127.1 119.4 139.5 117.9 120.4 124.2 118.9 121.3 121.4 124.0 136.9 86.5 128.2 131.0 18.6 144.3 111.3 148.9 165.9 129.1 94.9 69.1 65.0 68.5 98.7 141.5 66.2 89.6 195.9 131.8 114.3 92.0 172.2 278.2 119.5 103.2 104.4 82.5 113.6 19.2 214.8 183.7 117.6 95.8 92.0 120.8 119.0 80.7 72.4 124.9 107.7 19.3 112.4 130.2 103.6 115.0 78.5 120.2 103.8 65.8 10.3 195.6 122.1 155.5 12.1 28.9 158.9 96.3 130.1 198.3 136.6 101.1 108.1 214.7 109.4 78.9 106.1 153.7 220.1 172.0 103.2 99.0 186.6 145.5 118.7 122.3 130.8 SF3B4 "Hsh49, SAP49, SF3b49" ENSG00000143368 "Splicing factor 3b subunit 4" Q15427 1 149923317-149927803 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028578, HPA064660" Approved Approved "Nuclear speckles" NA NA 36000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "HPA028578: AB_10601601, HPA064660: AB_2685314" "unprognostic (2.43e-1)" "unprognostic (6.58e-2)" "unprognostic (2.49e-2)" "unprognostic (9.26e-3)" "unprognostic (2.74e-1)" "unprognostic (2.30e-2)" "prognostic unfavorable (1.54e-5)" "unprognostic (3.11e-1)" "unprognostic (2.04e-1)" "unprognostic (6.60e-2)" "unprognostic (2.12e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (1.74e-7)" "unprognostic (9.63e-2)" "unprognostic (6.54e-2)" "unprognostic (3.15e-2)" "unprognostic (1.91e-1)" 35.6 36.8 27.9 42.3 28.4 74.3 31.6 30.1 35.8 36.0 29.3 55.8 39.6 48.5 37.5 45.1 51.8 33.8 28.9 28.6 30.4 29.9 27.1 36.8 48.5 31.1 28.3 47.5 34.6 53.4 26.0 40.1 28.7 32.3 44.2 20.8 40.1 47.9 22.5 62.4 40.1 46.7 28.0 39.4 32.4 46.4 29.1 58.0 39.1 26.9 57.6 50.3 33.4 29.8 153.0 144.1 119.4 110.9 75.5 58.4 172.0 119.0 118.2 188.0 143.0 152.0 125.6 144.2 87.1 139.7 103.0 154.3 150.9 158.2 161.8 95.3 110.7 130.0 77.3 112.8 121.7 156.6 163.5 74.7 122.6 184.0 84.5 59.0 94.6 126.7 116.6 119.6 172.9 456.6 203.9 148.9 199.4 175.9 146.1 157.9 106.4 157.6 137.4 128.2 79.6 147.6 109.8 151.1 92.5 141.4 229.9 205.1 78.3 154.9 170.0 122.9 222.8 169.0 259.4 161.2 124.2 133.8 147.5 70.5 81.1 130.5 84.0 109.8 87.4 80.2 79.6 90.4 71.3 73.1 74.3 71.9 111.2 104.7 120.0 84.6 100.1 67.5 27.9 28.4 30.1 35.8 28.6 30.4 31.1 28.3 28.7 28.0 29.1 29.8 30.4 16.0 13.4 4.2 39.9 54.2 47.5 83.2 65.4 20.0 34.3 41.4 3.9 21.5 41.2 23.9 4.2 80.8 54.2 42.2 60.7 64.3 80.3 38.9 30.4 30.6 26.0 34.3 4.1 51.6 77.5 31.8 27.0 44.5 39.3 32.9 16.8 14.7 53.0 8.4 4.8 40.0 59.0 24.7 42.5 13.3 45.1 34.9 24.9 3.7 61.8 27.5 44.3 4.5 7.0 62.3 35.9 29.3 38.6 32.2 28.5 43.0 49.8 15.9 46.0 30.8 64.6 64.0 51.5 47.0 51.3 94.7 44.9 27.9 36.7 43.8 SFMBT2 KIAA1617 ENSG00000198879 "Scm like with four mbt domains 2" Q5VUG0 10 7158624-7411486 "Predicted intracellular proteins" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 27.7" "Cell type enriched" "Detected in many" 4 "Microglial cells: 618.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 4.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 23.0;REH: 21.0;RPMI-8226: 20.2;SH-SY5Y: 16.6;THP-1: 25.0;U-937: 16.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA035447, HPA035448, HPA070388" Uncertain Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 43: THP-1 - Innate immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Nuclear speckles" "HPA035447: AB_2674628, HPA035448: AB_10669904, HPA070388: " "unprognostic (4.36e-2)" "unprognostic (2.29e-2)" "unprognostic (4.36e-2)" "unprognostic (1.42e-3)" "unprognostic (3.23e-2)" "unprognostic (2.05e-3)" "unprognostic (4.65e-1)" "unprognostic (4.56e-1)" "unprognostic (1.03e-1)" "unprognostic (6.51e-2)" "unprognostic (5.57e-2)" "unprognostic (1.38e-1)" "unprognostic (2.41e-2)" "unprognostic (1.26e-1)" "unprognostic (9.17e-3)" "unprognostic (5.37e-3)" "unprognostic (7.29e-2)" 3.8 4.1 13.0 5.9 13.1 6.6 5.5 10.2 9.8 3.4 5.1 2.8 2.0 4.0 3.7 1.1 4.0 3.5 4.0 7.5 17.6 3.0 1.3 4.7 7.3 20.4 15.0 9.1 1.3 5.7 6.4 3.4 17.1 6.6 3.2 18.0 2.3 3.1 4.2 1.7 4.0 3.3 12.7 9.0 3.1 1.8 27.7 4.5 6.8 2.6 5.8 4.1 4.2 19.0 0.0 4.0 0.3 0.0 0.0 0.0 4.9 0.1 0.0 0.0 0.0 0.0 1.1 7.6 0.0 0.0 0.0 1.9 7.6 0.0 0.0 0.4 7.9 0.0 13.0 0.0 0.7 8.0 1.1 1.1 0.4 0.0 0.3 0.0 0.1 10.0 11.5 23.0 0.0 3.5 7.0 14.3 1.6 0.0 0.0 21.0 2.2 20.2 0.0 0.8 2.0 16.6 0.0 0.1 0.0 2.1 1.3 25.0 0.0 0.0 2.6 0.4 0.2 10.1 13.3 0.0 1.1 16.5 0.3 0.1 0.2 1.1 0.7 2.3 0.4 0.0 0.2 0.5 0.4 0.0 1.0 0.6 0.1 0.9 4.6 3.1 0.0 0.2 13.0 13.1 10.2 9.8 7.5 17.6 20.4 15.0 17.1 12.7 27.7 19.0 8.2 0.0 5.2 148.2 10.2 1.5 1.5 0.0 1.2 8.1 9.3 8.6 9.7 1.5 0.6 0.0 81.3 7.7 22.1 0.1 0.0 0.4 0.2 0.8 15.8 10.1 4.2 6.1 77.3 0.2 2.5 4.2 2.0 3.5 4.5 7.1 5.7 1.1 15.5 0.0 103.9 0.0 0.0 15.7 9.9 0.8 5.0 26.3 5.4 618.3 11.4 12.4 15.5 26.2 113.7 0.1 0.0 2.2 25.8 11.4 0.0 0.3 0.7 34.1 0.0 4.4 2.6 0.3 3.9 0.2 1.3 4.4 25.8 2.5 0.2 0.6 SGK1 SGK ENSG00000118515 "Serum/glucocorticoid regulated kinase 1" O00141 6 134169246-134318112 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 1007.1" "Cell type enhanced" "Detected in many" "Langerhans cells: 1238.4;Proximal enterocytes: 789.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 43.4;eosinophil: 170.2;neutrophil: 91.6" "Group enriched" "Detected in all" 8 "granulocytes: 170.2;monocytes: 43.4" "Cell line enhanced" "Detected in many" "HHSteC: 298.1;RPTEC TERT1: 469.5;SK-MEL-30: 319.7;TIME: 373.9;U-266/84: 358.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022085, CAB025148, HPA051251" Approved Enhanced "Nuclear speckles" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 41: Macrophages - Immune response" "Nuclear speckles" "CAB022085: , CAB025148: , HPA051251: AB_2681407" "unprognostic (2.05e-2)" "prognostic favorable (5.26e-4)" "unprognostic (1.12e-1)" "unprognostic (5.09e-3)" "unprognostic (2.76e-1)" "unprognostic (4.20e-2)" "unprognostic (4.53e-2)" "unprognostic (5.62e-2)" "unprognostic (4.03e-1)" "unprognostic (7.94e-2)" "unprognostic (1.78e-1)" "unprognostic (2.55e-1)" "unprognostic (5.82e-3)" "unprognostic (9.10e-2)" "unprognostic (3.81e-2)" "unprognostic (1.79e-1)" "unprognostic (6.59e-2)" 147.5 121.5 35.8 47.4 57.3 68.9 83.2 40.0 51.4 61.1 96.9 68.4 51.4 37.0 9.5 108.4 36.5 170.0 35.8 41.2 42.7 105.2 99.3 81.8 33.6 64.5 44.9 125.8 177.1 1007.1 12.0 70.6 49.6 47.6 39.0 14.1 70.8 60.3 50.2 75.7 282.5 48.4 35.8 21.5 104.2 30.4 53.6 39.7 56.7 33.9 78.1 141.3 96.7 94.0 4.1 6.9 4.2 0.4 51.7 12.9 5.9 76.7 159.4 98.4 79.8 12.2 10.6 13.1 11.3 79.8 48.0 2.5 6.8 12.2 72.0 0.5 3.1 0.6 175.7 9.2 298.1 0.7 6.8 77.3 75.4 96.7 124.3 39.3 167.1 2.3 25.6 192.8 35.6 0.6 1.1 3.0 4.8 20.3 8.3 2.4 8.9 1.5 469.5 1.4 2.2 18.6 241.7 0.7 319.7 43.2 0.5 2.1 373.9 28.8 12.3 176.9 17.1 36.2 358.5 40.3 26.7 12.0 39.5 2.2 43.4 170.2 0.7 24.4 1.6 1.9 1.3 0.8 14.1 1.4 1.6 2.0 91.6 3.6 14.5 0.9 2.5 12.6 35.8 57.3 40.0 51.4 41.2 42.7 64.5 44.9 49.6 35.8 53.6 94.0 346.2 38.5 177.8 34.0 68.0 183.3 133.7 277.3 329.0 12.0 87.1 112.0 28.4 88.6 168.6 68.0 35.5 41.0 27.0 132.2 21.5 81.3 9.6 145.8 73.1 232.1 10.7 14.7 68.2 171.2 33.6 88.8 206.4 483.4 271.8 33.9 353.4 21.9 284.2 0.0 225.7 65.1 91.6 181.3 1238.4 7.7 15.2 492.5 268.6 58.1 29.6 4.6 2.1 270.9 377.7 36.2 123.9 15.8 92.4 51.0 789.1 124.3 61.5 29.3 13.1 43.5 102.9 38.1 10.2 348.1 116.2 579.8 46.9 48.9 36.3 123.8 SHANK2 "CORTBP1, CTTNBP1, ProSAP1, SHANK, SPANK-3" ENSG00000162105 "SH3 and multiple ankyrin repeat domains 2" Q9UPX8 11 70467854-71252577 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 31.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 153.5;Horizontal cells: 136.3;Inhibitory neurons: 167.5" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 8 "amygdala: 7.7;basal ganglia: 7.5;cerebral cortex: 9.3;hippocampal formation: 9.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 11.5;Karpas-707: 17.5;RT4: 15.9;T-47d: 16.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008174, HPA017220" Approved Approved "Nuclear speckles,Vesicles,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Plasma membrane" "Nuclear speckles" "HPA008174: AB_1856822, HPA017220: " "unprognostic (3.08e-1)" "unprognostic (1.31e-3)" "unprognostic (1.79e-1)" "unprognostic (1.51e-2)" "unprognostic (1.51e-1)" "unprognostic (7.23e-5)" "unprognostic (1.24e-1)" "unprognostic (6.67e-2)" "unprognostic (1.83e-2)" "unprognostic (8.42e-2)" "unprognostic (4.87e-2)" "unprognostic (4.01e-1)" "prognostic favorable (1.94e-6)" "unprognostic (3.46e-2)" "unprognostic (2.34e-1)" "unprognostic (4.03e-2)" "unprognostic (4.80e-2)" 1.3 1.2 7.7 0.5 7.5 0.0 4.5 0.2 9.3 1.3 31.7 2.4 1.5 1.0 2.2 3.4 5.1 0.8 0.0 9.5 0.0 4.9 3.8 3.7 0.1 0.0 0.0 0.1 7.5 0.1 2.2 1.9 0.0 3.2 2.0 5.5 9.8 1.8 0.0 0.9 1.3 0.4 0.0 1.1 3.0 0.9 1.0 0.0 6.0 0.0 0.4 1.1 0.3 0.9 0.5 7.4 4.1 0.0 0.6 0.4 4.5 0.7 0.3 0.0 0.0 6.6 3.1 6.2 2.2 0.0 0.1 1.1 0.0 4.8 0.0 0.0 0.2 0.0 0.0 11.5 0.0 0.0 1.9 0.1 1.8 0.0 0.0 1.6 0.0 0.1 0.0 17.5 1.7 10.5 0.0 0.1 3.5 10.2 0.3 0.0 9.9 8.2 5.2 15.9 3.5 1.1 0.0 8.4 0.0 5.2 16.4 0.0 0.0 0.0 1.5 0.1 0.0 0.1 0.6 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 7.5 0.2 9.3 9.5 0.0 0.0 0.0 0.0 0.0 1.0 0.9 8.0 41.7 17.0 21.5 0.2 0.0 3.2 3.2 0.6 17.9 26.9 13.0 3.7 11.5 5.4 7.3 0.0 12.8 0.4 3.2 3.9 8.4 1.7 30.0 3.2 1.3 0.0 0.0 153.5 2.2 2.9 1.8 10.2 13.0 2.5 1.2 0.4 21.9 1.2 136.3 167.5 7.9 8.2 0.0 0.3 2.1 0.0 0.4 5.4 14.0 0.0 4.6 0.0 41.7 5.3 10.7 2.7 0.7 0.4 10.9 0.6 10.8 23.3 1.0 0.0 0.3 1.3 0.7 0.9 1.3 0.6 14.6 0.3 0.1 5.5 4.0 SHPK "CARKL, SHK" ENSG00000197417 Sedoheptulokinase Q9UHJ6 17 3608240-3636250 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 19.1;Proximal enterocytes: 18.9;Rod photoreceptor cells: 18.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA024361, HPA064939" Enhanced Approved "Nucleoplasm,Nuclear speckles" NA NA 350000 "Cluster 40: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Nuclear speckles" "HPA024361: AB_1846030, HPA064939: AB_2685388" "unprognostic (1.75e-2)" "unprognostic (1.51e-2)" "unprognostic (3.53e-2)" "unprognostic (1.23e-2)" "unprognostic (3.57e-3)" "unprognostic (1.54e-2)" "unprognostic (1.95e-2)" "unprognostic (3.01e-2)" "unprognostic (1.56e-1)" "unprognostic (3.64e-2)" "unprognostic (1.08e-2)" "unprognostic (1.42e-1)" "unprognostic (3.82e-2)" "unprognostic (6.75e-2)" "unprognostic (1.55e-1)" "unprognostic (1.05e-1)" "unprognostic (1.12e-1)" 7.4 9.9 3.5 3.9 5.0 4.8 6.9 4.1 4.4 9.8 3.1 6.4 13.5 4.8 2.9 9.4 6.2 3.6 4.5 3.4 3.5 10.2 23.3 4.7 3.9 3.9 4.8 7.5 10.9 8.6 4.5 6.2 4.2 5.7 6.0 7.1 7.0 5.4 3.3 9.7 11.5 3.5 3.0 4.4 8.4 4.2 4.3 4.5 5.5 3.3 5.3 5.6 7.8 8.7 6.7 13.5 14.0 9.1 5.7 5.7 7.8 4.4 4.0 8.5 5.0 23.3 6.2 7.9 9.5 8.6 7.9 12.8 18.8 14.3 6.1 12.8 18.3 8.6 11.6 17.0 6.9 7.6 11.8 9.7 6.8 9.4 6.3 7.2 16.1 6.2 11.6 9.8 8.3 12.0 9.8 5.9 7.0 15.3 8.9 13.3 7.3 12.6 12.0 8.5 4.1 10.7 16.2 14.7 4.6 8.4 13.2 4.4 11.6 12.8 6.1 12.5 10.9 3.3 4.5 5.2 13.9 6.7 6.7 1.5 2.2 2.5 1.9 2.3 2.0 2.1 1.8 1.6 3.0 1.5 3.0 1.9 0.4 3.2 1.8 3.2 1.6 2.5 3.5 5.0 4.1 4.4 3.4 3.5 3.9 4.8 4.2 3.0 4.3 8.7 2.6 0.0 3.2 11.1 2.0 0.0 1.0 0.1 3.4 5.9 3.2 2.3 1.0 4.3 0.8 5.5 16.7 10.0 1.1 9.2 1.9 3.3 0.5 2.6 2.5 2.9 3.5 5.2 4.5 4.7 10.1 3.3 4.6 2.9 0.0 5.0 3.6 19.1 8.4 15.2 5.3 6.0 0.0 2.2 0.4 0.4 4.1 2.2 0.0 8.4 2.7 2.5 1.0 4.0 8.2 5.3 6.7 2.6 2.0 2.2 18.9 8.5 1.0 18.2 0.0 4.8 1.8 0.6 1.2 3.0 0.4 5.6 2.1 16.9 6.5 1.8 SIK2 "DKFZp434K1115, KIAA0781, LOH11CR1I, QIK, SNF1LK2" ENSG00000170145 "Salt inducible kinase 2" Q9H0K1 11 111602449-111730855 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 113.3;Excitatory neurons: 217.6;Inhibitory neurons: 132.4;Oligodendrocytes: 191.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "ASC diff: 50.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016026, HPA071049" Approved Approved "Nucleoplasm,Nuclear speckles,Vesicles,Intermediate filaments,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Vesicles" "Nuclear speckles, Intermediate filaments, Cytosol" "HPA016026: AB_1857321, HPA071049: " "unprognostic (2.35e-1)" "unprognostic (1.10e-1)" "unprognostic (1.08e-1)" "unprognostic (1.10e-2)" "unprognostic (1.59e-2)" "unprognostic (4.81e-2)" "prognostic favorable (4.93e-4)" "unprognostic (6.41e-2)" "unprognostic (1.87e-1)" "unprognostic (1.40e-2)" "unprognostic (3.72e-3)" "unprognostic (9.27e-2)" "prognostic favorable (1.17e-9)" "unprognostic (1.23e-1)" "unprognostic (2.79e-1)" "unprognostic (2.82e-3)" "unprognostic (2.13e-2)" 29.7 9.3 9.2 5.3 12.4 3.1 20.7 7.9 11.1 7.6 11.0 7.9 5.9 7.3 5.0 5.9 8.1 10.0 12.3 9.5 14.7 11.4 22.7 11.7 4.4 11.9 11.9 14.9 31.8 21.3 16.6 5.8 10.6 6.7 6.2 30.7 13.8 6.2 33.1 8.9 7.5 5.9 5.5 4.6 17.6 3.0 9.3 5.4 8.7 23.2 4.3 7.7 6.1 11.6 9.2 6.0 10.3 11.1 50.3 14.8 6.1 7.9 11.2 5.9 6.7 20.5 9.6 7.2 10.7 9.2 6.9 12.7 8.2 5.9 7.6 5.4 3.4 7.9 5.2 10.1 10.9 7.7 4.9 14.5 8.6 8.7 11.1 11.7 7.1 7.1 7.4 10.3 9.4 4.3 8.0 7.0 3.5 7.6 5.9 10.6 11.0 8.7 13.1 8.2 4.8 11.3 11.6 4.7 4.5 9.4 11.5 6.2 9.9 12.9 7.7 8.3 10.9 2.9 2.4 14.8 4.2 10.6 8.8 0.3 0.7 0.6 0.7 0.7 0.3 0.4 0.5 0.5 0.6 0.4 0.2 0.4 0.3 0.5 0.6 0.3 0.5 0.5 9.2 12.4 7.9 11.1 9.5 14.7 11.9 11.9 10.6 5.5 9.3 11.6 22.1 19.2 24.8 113.3 14.1 14.7 6.2 5.2 18.2 15.7 10.5 9.9 21.3 27.1 10.0 16.5 66.7 4.4 11.4 15.6 5.9 10.4 16.5 27.7 14.9 18.8 18.0 12.4 217.6 7.9 4.6 20.1 27.5 45.3 9.5 24.3 9.3 38.7 5.4 32.0 132.4 11.3 4.1 12.4 16.9 14.1 11.5 13.3 19.6 73.1 6.0 14.5 4.1 86.0 191.9 8.4 10.3 14.7 8.9 6.9 8.3 23.1 13.4 60.9 0.0 19.1 19.0 3.9 6.4 10.3 11.9 5.2 12.6 5.0 11.5 7.1 SIM1 bHLHe14 ENSG00000112246 "SIM bHLH transcription factor 1" P81133 6 100385009-100464921 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.4;kidney: 9.9;skeletal muscle: 3.5" "Cell type enhanced" "Detected in some" "Collecting duct cells: 20.2;Distal tubular cells: 7.9;Ductal cells: 4.5;Skeletal myocytes: 7.6" "Cancer enhanced" "Detected in single" "renal cancer: 1.8" "Group enriched" "Detected in some" 5 "hypothalamus: 4.4;midbrain: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 9.7;BJ: 16.4;BJ hTERT+: 23.7;BJ hTERT+ SV40 Large T+: 7.2;HDLM-2: 7.3;RPTEC TERT1: 18.4" "Region enriched" "Detected in single" 8 "hypothalamus: 5.2" "Region enhanced" "Detected in some" "hypothalamus: 3.1" HPA024385 Approved "Nuclear speckles" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 37: Myocytes - Muscle contraction" "Nuclear speckles" "HPA024385: AB_1856879" "unprognostic (1.04e-1)" "unprognostic (4.34e-3)" "unprognostic (2.24e-1)" "unprognostic (1.51e-1)" "unprognostic (4.34e-1)" "unprognostic (1.38e-1)" "unprognostic (2.85e-1)" "unprognostic (4.64e-2)" "unprognostic (3.76e-2)" "prognostic favorable (5.32e-7)" "unprognostic (1.00e-1)" "unprognostic (1.19e-1)" 1.7 0.0 0.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 4.4 9.9 0.3 0.0 0.0 0.0 1.2 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 3.5 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.5 9.7 0.0 16.4 23.7 7.2 6.7 0.0 0.0 0.0 0.0 5.2 1.5 0.0 0.0 0.0 6.1 7.3 2.2 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 18.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.3 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 4.4 0.0 1.2 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 20.2 0.0 0.1 0.0 0.0 7.9 4.5 1.8 0.1 0.1 0.1 1.8 0.0 0.1 1.2 0.1 1.5 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 7.6 0.3 1.5 0.1 0.0 0.4 0.0 0.1 0.0 0.0 0.1 SIRT7 ENSG00000187531 "Sirtuin 7" Q9NRC8 17 81911939-81921323 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Chromatin regulator, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 152.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 22.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027284, HPA028246, CAB037261, HPA053669" Approved Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nuclear speckles" "CAB037261: AB_1079989, HPA027284: , HPA028246: , HPA053669: AB_2682224" "unprognostic (8.15e-3)" "unprognostic (3.24e-2)" "unprognostic (3.26e-2)" "unprognostic (2.41e-2)" "unprognostic (1.46e-1)" "unprognostic (3.36e-2)" "prognostic unfavorable (1.97e-5)" "unprognostic (3.03e-1)" "unprognostic (2.10e-1)" "unprognostic (2.46e-2)" "unprognostic (2.79e-1)" "unprognostic (1.71e-2)" "prognostic unfavorable (1.69e-7)" "unprognostic (4.34e-3)" "unprognostic (1.20e-1)" "unprognostic (4.77e-2)" "unprognostic (2.16e-2)" 8.8 8.0 6.8 7.4 7.3 23.2 8.6 7.5 8.6 12.5 7.4 17.3 12.9 7.0 1.9 42.1 8.0 5.4 6.4 6.9 6.7 11.5 14.2 9.6 11.8 7.6 7.0 6.0 12.8 5.4 6.9 4.2 7.4 9.8 5.8 0.6 14.1 3.7 6.2 22.4 17.1 3.6 7.0 18.7 17.9 13.3 7.6 9.4 7.9 3.7 7.2 10.8 18.0 7.6 26.5 21.7 2.8 9.5 6.9 6.4 17.0 13.1 10.8 15.1 14.1 18.7 20.7 11.8 9.9 7.3 9.6 18.8 10.5 8.1 4.9 10.2 22.9 10.4 10.7 29.7 20.4 13.6 20.5 6.5 25.0 14.5 11.9 6.4 11.3 6.5 11.3 5.8 7.2 20.9 14.6 19.5 6.8 40.6 22.3 9.7 5.5 11.1 14.7 17.4 11.1 14.6 15.0 35.9 17.7 5.0 15.1 32.1 9.0 6.8 14.9 12.9 24.2 9.5 3.2 9.0 16.6 18.4 11.3 4.5 2.6 22.2 2.8 3.8 0.9 4.5 2.1 2.3 1.4 7.0 2.0 0.7 4.4 1.8 3.3 2.1 1.2 1.5 6.8 7.3 7.5 8.6 6.9 6.7 7.6 7.0 7.4 7.0 7.6 7.6 15.2 12.8 12.2 12.4 41.4 38.0 25.8 21.1 28.5 23.4 27.4 19.0 4.4 18.6 18.7 18.4 56.3 31.1 62.8 99.0 9.8 22.4 21.8 28.8 14.0 15.4 20.4 16.0 14.3 13.6 33.2 12.4 152.9 37.0 11.4 20.1 15.0 16.0 26.1 30.3 10.6 34.6 28.5 26.4 33.5 14.1 14.3 29.4 24.9 5.6 47.3 14.7 71.1 6.6 13.8 52.7 74.5 10.1 33.2 29.1 74.7 16.0 29.6 39.1 0.0 12.5 15.5 41.3 37.4 52.4 55.5 49.3 50.8 17.9 44.6 53.9 SLC25A12 Aralar ENSG00000115840 "Solute carrier family 25 member 12" O75746 2 171783405-171999859 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 97.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 97.7;Excitatory neurons: 148.5;Inhibitory neurons: 175.2;Oligodendrocyte precursor cells: 111.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035333, HPA035334" Enhanced Uncertain "Nuclear speckles,Cytosol" NA NA 9100 "Cluster 32: T-cells - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear speckles" Cytosol "HPA035333: AB_10603028, HPA035334: AB_2674577" "unprognostic (3.24e-2)" "unprognostic (2.52e-2)" "unprognostic (4.07e-2)" "prognostic unfavorable (7.86e-4)" "unprognostic (2.65e-2)" "unprognostic (7.27e-2)" "unprognostic (4.21e-3)" "unprognostic (5.23e-2)" "unprognostic (1.39e-1)" "unprognostic (4.96e-2)" "unprognostic (7.76e-2)" "unprognostic (1.13e-1)" "prognostic favorable (2.91e-8)" "unprognostic (8.64e-3)" "unprognostic (2.08e-1)" "unprognostic (1.73e-1)" "unprognostic (2.70e-1)" 11.1 11.5 8.5 4.0 9.0 2.8 11.6 9.3 12.3 11.5 6.1 25.2 2.2 13.4 4.3 12.7 11.7 3.7 62.7 8.9 9.0 13.4 1.8 7.1 4.4 6.9 6.7 14.5 3.9 12.0 17.1 3.2 6.8 13.7 6.1 15.8 16.8 9.5 97.0 14.5 10.7 8.5 5.8 8.9 16.4 6.1 7.4 5.6 15.1 51.1 5.2 16.2 12.4 8.4 4.9 3.0 4.2 8.0 9.5 11.7 0.0 5.3 11.2 7.7 7.3 2.2 3.2 14.5 2.6 7.5 4.3 4.3 7.9 8.5 10.7 6.3 10.4 6.9 4.4 5.5 3.8 14.8 4.9 12.6 7.0 11.0 2.3 4.1 8.0 7.0 5.0 5.2 4.4 3.2 9.7 6.5 3.0 3.8 4.7 9.6 4.7 7.4 8.0 4.5 5.1 1.6 2.6 8.5 4.0 2.5 2.8 3.1 6.4 6.2 2.0 6.0 3.2 8.8 4.2 13.6 9.1 7.5 2.9 0.0 0.4 0.1 1.0 0.4 0.8 0.7 0.5 0.9 0.4 0.5 0.9 1.5 0.0 0.9 0.7 0.1 0.7 0.4 8.5 9.0 9.3 12.3 8.9 9.0 6.9 6.7 6.8 5.8 7.4 8.4 9.8 0.0 9.8 71.2 11.3 6.9 10.2 13.2 19.9 25.5 9.3 11.8 97.7 0.0 18.4 18.4 25.0 7.5 10.7 11.6 19.6 1.7 3.2 5.0 10.3 8.7 14.4 6.9 148.5 3.3 1.8 15.1 12.8 6.1 10.8 7.3 7.9 0.6 4.5 37.0 175.2 6.1 16.2 8.4 5.4 2.1 12.5 7.2 16.0 25.3 9.7 19.8 5.2 111.6 44.1 2.0 4.7 24.5 19.5 4.6 4.1 13.2 11.2 25.5 13.1 12.5 16.6 7.8 9.1 16.8 7.7 1.2 15.0 11.0 7.6 8.3 SLC28A1 CNT1 ENSG00000156222 "Solute carrier family 28 member 1" O00337 15 84884654-84945798 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "intestine: 49.1;kidney: 48.2;liver: 111.3" "Group enriched" "Detected in some" 5 "Hepatocytes: 38.6;Hofbauer cells: 54.3;Proximal enterocytes: 86.9;Proximal tubular cells: 93.4" "Group enriched" "Detected in some" 63 "liver cancer: 10.9;renal cancer: 33.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA019551, HPA056247" Enhanced Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "Nuclear speckles, Cytosol" "HPA019551: AB_2670187, HPA056247: " "unprognostic (3.81e-2)" "unprognostic (1.60e-1)" "unprognostic (2.22e-1)" "unprognostic (7.49e-2)" "unprognostic (5.08e-2)" "unprognostic (7.08e-2)" "unprognostic (8.68e-3)" "unprognostic (1.82e-1)" "unprognostic (1.98e-1)" "unprognostic (2.18e-2)" "unprognostic (1.63e-1)" "unprognostic (8.37e-2)" "unprognostic (1.35e-1)" "unprognostic (7.42e-2)" "unprognostic (7.72e-3)" "unprognostic (6.65e-2)" "unprognostic (1.55e-1)" 0.2 0.0 0.0 0.1 0.2 0.0 0.1 0.2 0.1 0.3 0.0 0.0 37.9 0.0 0.5 0.1 0.7 0.2 1.0 0.1 0.3 48.2 111.3 0.0 0.2 0.9 0.3 0.0 0.0 0.2 0.2 1.2 0.7 0.0 0.0 0.0 0.1 0.0 1.5 0.0 49.1 0.0 0.4 0.0 0.1 0.1 0.2 0.0 0.0 3.3 0.0 0.0 0.0 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.1 0.3 0.9 0.3 0.7 0.4 0.2 0.6 0.2 0.0 0.0 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.5 0.3 2.2 4.3 0.6 7.3 0.0 0.5 0.0 0.0 11.7 3.0 0.0 0.4 0.1 0.1 0.0 0.0 0.5 0.0 0.5 0.4 0.0 0.6 0.0 0.0 0.4 38.6 54.3 0.0 0.5 2.8 0.0 0.6 0.0 0.0 0.0 0.9 0.0 0.0 0.6 0.0 0.0 0.5 1.1 0.3 2.5 0.0 0.0 0.0 86.9 93.4 1.4 0.0 0.0 2.6 0.2 0.0 0.0 0.0 0.0 0.8 0.4 0.3 1.5 0.1 SLC2A4RG "GEF, HDBP1, Si-1-2, Si-1-2-19" ENSG00000125520 "SLC2A4 regulator" Q9NR83 20 63739776-63744050 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 150.6" "Cell type enhanced" "Detected in all" "Hepatocytes: 116.2;Proximal tubular cells: 160.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063050 Approved "Nuclear speckles" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 85: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles" "HPA063050: AB_2684930" "unprognostic (2.89e-2)" "unprognostic (2.32e-1)" "unprognostic (1.84e-2)" "unprognostic (5.78e-2)" "unprognostic (2.07e-3)" "unprognostic (6.48e-3)" "unprognostic (2.70e-1)" "unprognostic (1.96e-2)" "unprognostic (1.31e-1)" "unprognostic (3.44e-2)" "unprognostic (2.09e-3)" "unprognostic (1.50e-1)" "unprognostic (1.39e-2)" "unprognostic (1.41e-1)" "unprognostic (1.12e-1)" "unprognostic (1.50e-3)" "unprognostic (3.22e-1)" 59.4 37.9 8.8 3.1 8.6 10.2 45.0 7.3 12.8 42.0 7.7 55.5 1.6 39.2 4.2 47.7 35.0 3.3 60.5 8.3 8.4 67.8 150.6 30.9 5.0 8.4 8.2 45.8 28.4 5.6 23.0 2.8 7.6 50.1 1.5 2.3 27.3 10.5 88.2 60.8 25.6 3.3 8.6 35.5 33.4 24.2 8.2 6.3 32.1 18.7 3.0 50.2 40.6 8.6 20.5 26.4 12.2 11.0 7.6 14.9 11.9 16.6 16.4 43.8 15.2 49.0 34.0 4.3 23.1 12.1 18.9 24.1 6.1 20.0 7.6 13.5 11.0 4.3 19.4 25.8 16.2 10.5 8.9 17.4 29.0 11.8 9.5 8.7 12.8 3.9 15.8 4.7 21.3 37.0 5.9 29.8 5.3 21.9 59.6 29.4 21.8 10.5 17.3 7.8 10.8 19.0 35.4 16.0 4.5 4.6 37.9 33.7 11.0 43.4 22.7 25.2 13.1 12.8 27.0 7.3 18.1 12.4 11.8 0.0 0.0 0.2 0.9 0.0 0.4 0.1 0.9 0.5 0.1 0.0 0.7 0.7 0.0 0.3 0.1 0.2 1.1 0.1 8.8 8.6 7.3 12.8 8.3 8.4 8.4 8.2 7.6 8.6 8.2 8.6 35.9 9.6 21.2 21.5 16.0 24.5 25.0 19.3 19.4 10.1 44.7 61.5 21.3 37.1 11.2 42.3 10.4 30.7 60.1 18.3 78.2 8.2 9.2 16.3 57.1 22.2 2.4 55.4 5.5 10.3 16.6 49.7 12.8 32.4 3.8 52.6 19.6 116.2 14.7 10.1 4.5 17.5 14.2 13.5 12.7 4.3 28.9 14.6 3.6 5.6 11.7 33.5 13.4 8.0 7.1 20.3 7.8 34.6 16.9 14.9 10.5 160.8 6.1 6.5 32.9 26.1 32.9 1.1 6.4 29.3 37.8 8.6 46.3 77.0 15.0 18.3 SLC31A2 "COPT2, CTR2, hCTR2" ENSG00000136867 "Solute carrier family 31 member 2" O15432 9 113150976-113164140 "Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "parathyroid gland: 571.4;salivary gland: 409.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 96.4;Kupffer cells: 145.6;Macrophages: 101.3;monocytes: 84.1;Oligodendrocytes: 113.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 12 "classical monocyte: 226.0;intermediate monocyte: 331.9;myeloid DC: 134.6;neutrophil: 355.8;non-classical monocyte: 423.3" "Group enriched" "Detected in all" 47 "dendritic cells: 134.6;granulocytes: 355.8;monocytes: 423.3" "Cell line enhanced" "Detected in many" "ASC diff: 54.4;hTCEpi: 85.0;hTERT-HME1: 57.7;LHCN-M2: 68.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014861 Approved Approved "Nuclear speckles,Plasma membrane,Intermediate filaments" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" "Nuclear speckles" "Plasma membrane, Intermediate filaments" "HPA014861: AB_1857098" "unprognostic (2.26e-1)" "unprognostic (7.20e-2)" "unprognostic (3.79e-3)" "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (4.81e-3)" "unprognostic (5.63e-2)" "unprognostic (3.31e-2)" "unprognostic (2.24e-1)" "unprognostic (3.44e-2)" "unprognostic (1.47e-1)" "unprognostic (1.86e-1)" "unprognostic (6.05e-3)" "unprognostic (1.76e-1)" "unprognostic (3.56e-2)" "unprognostic (1.25e-1)" "unprognostic (8.89e-2)" 48.2 16.7 45.0 18.4 72.6 20.1 24.4 68.2 77.8 7.3 34.2 11.3 10.8 4.4 16.7 9.3 6.9 8.6 10.3 45.1 54.0 27.8 33.4 27.4 16.1 76.6 65.8 5.1 19.2 571.4 2.5 23.6 71.4 4.4 12.1 0.8 409.1 42.6 16.7 48.2 17.2 10.8 61.5 32.7 11.8 13.8 61.7 12.1 6.3 14.6 17.6 13.3 10.7 108.2 7.8 3.1 1.3 1.7 54.4 22.3 6.5 4.0 13.9 12.8 12.3 2.4 1.5 0.3 0.5 9.1 7.9 37.7 5.1 31.0 12.0 2.2 1.3 0.1 1.2 3.3 20.7 1.9 0.8 25.3 85.0 30.0 57.7 1.8 6.9 3.0 1.4 2.6 68.9 6.5 1.6 0.7 0.4 1.8 2.6 0.2 39.3 0.0 4.5 4.2 0.9 2.5 6.9 36.4 1.4 0.8 8.6 2.5 2.4 2.0 1.9 13.7 3.2 2.1 5.0 0.1 12.5 3.2 2.0 5.1 226.0 24.0 4.3 331.9 6.5 1.2 4.9 5.2 134.6 1.0 3.8 3.9 355.8 1.0 423.3 2.1 3.0 104.9 45.0 72.6 68.2 77.8 45.1 54.0 76.6 65.8 71.4 61.5 61.7 108.2 13.8 9.6 9.2 2.3 7.0 37.1 6.4 37.7 13.6 7.0 15.3 10.8 0.6 4.3 10.9 1.8 35.5 96.4 3.6 12.8 3.9 13.5 4.1 23.5 4.9 6.4 3.5 0.4 2.1 7.7 9.0 14.4 3.6 8.4 0.0 2.7 12.8 18.1 57.2 6.7 1.8 4.5 10.2 145.6 65.6 4.6 15.8 101.3 0.0 4.7 84.1 6.9 3.1 0.5 113.7 18.5 11.0 9.4 9.1 10.2 51.3 18.2 14.8 9.1 19.7 8.7 7.8 31.0 5.2 3.3 38.4 43.1 7.9 4.6 5.7 7.6 SLC34A1 "NAPI-3, NPT2, NPTIIa, SLC11, SLC17A2" ENSG00000131183 "Solute carrier family 34 member 1" Q06495 5 177379235-177398848 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 54 "kidney: 155.4" "Cell type enriched" "Detected in some" 14 "Proximal tubular cells: 143.2" "Cancer enriched" "Detected in single" 12 "renal cancer: 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "HEL: 2.4;U-937: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA051255, HPA077175" Approved Approved "Nucleoplasm,Nuclear speckles,Plasma membrane,Mitotic spindle,Cytosol" Yes NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 36: HEL - Hemostasis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles, Plasma membrane" "Nucleoplasm, Mitotic spindle, Cytosol" "HPA051255: AB_2681409, HPA077175: " "unprognostic (1.17e-1)" "unprognostic (3.33e-3)" "unprognostic (1.49e-1)" "unprognostic (3.49e-2)" "unprognostic (1.56e-3)" "unprognostic (2.28e-1)" "unprognostic (4.50e-2)" "unprognostic (4.43e-3)" "unprognostic (1.91e-1)" "unprognostic (1.14e-1)" "unprognostic (5.95e-2)" "unprognostic (1.23e-3)" "unprognostic (1.38e-1)" "unprognostic (2.01e-1)" "unprognostic (1.28e-2)" "unprognostic (4.66e-2)" 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 155.4 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 7.3 0.0 0.0 0.2 0.0 9.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 143.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.6 0.0 0.0 0.1 SLC4A2 "AE2, BND3L, EPB3L1, HKB3, NBND3" ENSG00000164889 "Solute carrier family 4 member 2" P04920 7 151057210-151076526 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Anion exchange, Antiport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "choroid plexus: 492.1" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 91.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019339 Enhanced Uncertain "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Nuclear speckles, Plasma membrane" Cytosol "HPA019339: AB_1844825" "unprognostic (1.19e-1)" "unprognostic (3.33e-3)" "unprognostic (8.12e-3)" "unprognostic (1.10e-1)" "unprognostic (1.20e-1)" "unprognostic (1.49e-1)" "prognostic unfavorable (9.04e-6)" "unprognostic (1.24e-1)" "unprognostic (4.23e-1)" "unprognostic (3.30e-1)" "unprognostic (1.07e-1)" "unprognostic (3.21e-1)" "prognostic favorable (1.26e-4)" "unprognostic (4.67e-3)" "unprognostic (1.22e-1)" "unprognostic (1.28e-1)" "unprognostic (2.36e-2)" 28.4 34.8 16.9 19.2 29.4 12.7 23.7 29.1 21.9 38.9 492.1 45.0 22.5 40.3 4.9 21.0 31.1 19.7 31.3 39.4 23.2 38.6 52.3 33.2 13.1 32.8 27.9 31.9 52.5 72.4 13.8 27.0 32.0 28.2 7.1 4.7 23.1 14.0 18.8 21.7 29.3 16.5 20.2 27.0 82.2 13.7 32.7 12.4 25.4 12.3 6.3 31.9 25.8 40.2 60.9 196.9 37.8 78.9 37.6 17.9 87.1 72.9 37.0 56.9 48.0 113.0 91.6 35.8 154.1 35.0 84.6 58.2 38.2 31.4 9.8 105.3 59.1 48.5 91.9 57.5 59.6 25.2 147.0 29.0 27.4 65.6 15.7 60.9 31.3 50.6 151.8 27.1 44.3 118.0 69.2 43.3 90.4 80.7 73.2 55.2 21.2 42.2 44.6 41.0 31.5 113.9 67.0 118.4 62.0 27.3 51.2 46.7 72.0 78.1 39.1 77.5 106.5 31.2 47.7 20.5 118.7 61.4 160.6 0.0 1.6 0.4 0.8 1.6 0.7 0.9 0.7 0.7 1.0 0.3 0.7 0.8 0.2 0.1 1.0 2.1 0.2 0.9 16.9 29.4 29.1 21.9 39.4 23.2 32.8 27.9 32.0 20.2 32.7 40.2 15.6 9.6 8.2 9.8 7.2 11.1 5.9 13.6 15.4 7.7 14.5 11.9 4.0 18.6 9.6 20.2 25.0 36.1 14.2 17.6 17.6 35.7 1.0 21.9 18.9 13.6 27.6 2.5 0.4 35.8 9.4 13.6 30.1 17.0 47.1 62.1 17.9 34.6 26.0 15.2 1.4 12.1 16.2 16.1 12.0 1.6 13.7 17.0 26.6 4.7 11.6 21.6 3.1 3.0 16.8 43.8 14.0 19.9 9.9 5.9 24.9 19.1 11.4 8.2 13.1 12.8 17.6 3.1 7.9 10.6 7.0 91.5 8.5 11.2 22.1 4.5 SLC9C2 "MGC43026, SLC9A11" ENSG00000162753 "Solute carrier family 9 member C2 (putative)" Q5TAH2 1 173500460-173603072 "Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.3;choroid plexus: 1.9;testis: 6.0" "Cell type enriched" "Detected in some" 4 "Astrocytes: 27.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA059122, HPA079529" Enhanced Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane" "Nuclear speckles" "HPA059122: , HPA079529: " "unprognostic (2.10e-1)" "unprognostic (2.69e-1)" "unprognostic (8.52e-2)" "unprognostic (5.88e-3)" "unprognostic (3.24e-2)" "unprognostic (2.21e-1)" "unprognostic (1.29e-3)" "unprognostic (1.19e-1)" "unprognostic (4.21e-2)" "unprognostic (4.92e-1)" "unprognostic (1.88e-1)" "unprognostic (1.18e-6)" "unprognostic (1.66e-1)" "unprognostic (1.01e-2)" "unprognostic (2.98e-1)" "unprognostic (1.81e-1)" 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.2 0.2 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 1.3 1.2 0.2 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.1 6.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.5 0.2 0.2 0.5 0.3 1.3 1.2 0.8 0.8 0.4 0.6 0.0 0.0 0.0 27.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.6 0.0 1.3 0.0 6.2 0.1 1.3 0.1 0.0 0.1 6.2 1.7 0.1 0.4 0.0 0.0 5.0 0.0 0.5 0.3 0.0 0.1 0.0 0.5 0.4 1.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 4.7 0.0 0.7 0.0 1.5 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.1 0.1 5.4 0.4 0.0 0.0 0.1 0.0 1.3 0.0 0.0 SLU7 9G8 ENSG00000164609 "SLU7 homolog, splicing factor" O95391 5 160401641-160421711 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035907, HPA058120" Uncertain Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 6: Brain - Smell perception" "Cluster 44: HDLM-2 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Nuclear speckles" "HPA035907: AB_10671717, HPA058120: AB_2683612" "unprognostic (3.70e-2)" "unprognostic (7.18e-2)" "unprognostic (1.86e-2)" "unprognostic (9.96e-3)" "unprognostic (8.01e-2)" "unprognostic (3.52e-1)" "unprognostic (3.38e-3)" "unprognostic (3.76e-2)" "unprognostic (2.22e-2)" "unprognostic (2.42e-1)" "unprognostic (1.93e-1)" "unprognostic (7.69e-2)" "prognostic favorable (1.98e-4)" "unprognostic (2.65e-1)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" "unprognostic (1.25e-1)" 22.1 23.2 26.2 19.5 27.2 48.6 27.4 27.7 46.6 21.1 22.3 20.8 17.0 19.9 25.9 21.9 18.0 18.7 25.8 28.3 26.7 24.4 24.4 23.3 27.3 25.6 27.2 21.3 16.4 24.6 10.9 21.1 26.0 21.2 20.9 29.4 24.7 19.7 32.6 22.6 21.5 18.2 24.6 27.9 23.4 27.2 26.6 30.4 32.2 33.0 31.3 21.5 12.1 28.9 24.5 29.6 26.0 36.2 33.4 35.1 33.1 33.9 49.3 35.9 43.8 40.1 29.1 39.5 34.2 36.6 36.9 27.0 22.9 37.7 45.2 65.1 33.0 29.4 39.0 26.2 33.7 49.8 34.9 38.1 34.3 33.8 38.1 37.7 25.7 35.3 26.7 36.0 33.2 21.5 24.7 32.1 18.6 25.2 26.5 21.4 53.4 40.4 31.6 37.8 30.9 42.7 40.1 35.6 62.2 21.6 47.7 46.4 32.7 34.5 18.2 26.1 36.3 40.1 48.8 34.9 51.2 33.1 33.4 49.9 22.2 39.2 26.7 24.9 25.5 30.0 25.2 27.2 20.2 26.1 27.2 26.7 54.2 33.9 36.5 21.6 29.4 22.8 26.2 27.2 27.7 46.6 28.3 26.7 25.6 27.2 26.0 24.6 26.6 28.9 42.7 67.3 67.8 9.8 53.7 44.7 39.9 55.5 24.5 70.2 25.7 26.3 71.4 24.3 57.1 25.8 25.0 38.1 70.9 34.1 50.9 52.2 126.2 43.0 41.6 44.1 39.5 68.8 19.8 55.8 39.7 43.0 17.9 51.3 46.3 34.7 35.3 24.6 38.4 57.2 18.3 34.7 54.9 47.3 57.3 34.3 47.8 46.9 65.8 20.6 65.8 61.6 64.9 9.0 15.2 50.5 45.3 47.4 33.1 40.0 39.8 39.5 62.0 49.4 46.0 49.6 50.1 88.9 54.6 27.4 41.5 94.1 52.0 41.9 27.8 52.5 SMC4 "CAP-C, hCAP-C, SMC4L1" ENSG00000113810 "Structural maintenance of chromosomes 4" Q9NTJ3 3 160399274-160434954 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 60.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 305.8;Spermatocytes: 339.8;Spermatogonia: 239.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "basophil: 74.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029449, CAB055509" Approved Supported "Nuclear speckles,Cytosol" NA Yes 25000 "Cluster 18: Basophils - Vesicular transport" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear speckles, Cytosol" "CAB055509: , HPA029449: AB_10603891" "unprognostic (2.63e-1)" "unprognostic (1.01e-1)" "unprognostic (2.45e-2)" "prognostic unfavorable (7.63e-4)" "unprognostic (2.22e-1)" "unprognostic (1.28e-2)" "prognostic unfavorable (2.94e-4)" "unprognostic (9.54e-2)" "unprognostic (2.18e-2)" "unprognostic (5.47e-2)" "prognostic unfavorable (4.20e-5)" "prognostic unfavorable (9.00e-4)" "prognostic unfavorable (8.05e-7)" "unprognostic (3.03e-2)" "unprognostic (4.46e-1)" "unprognostic (1.06e-1)" "unprognostic (4.98e-2)" 6.8 6.5 1.0 21.2 2.0 36.3 6.8 1.2 1.7 6.3 1.5 13.2 14.0 7.4 2.3 23.5 4.5 7.6 7.3 0.9 1.9 5.9 7.8 11.8 37.1 1.7 1.4 5.9 7.8 3.8 2.0 16.2 1.6 5.8 14.9 7.7 4.6 5.0 3.6 11.0 15.4 10.1 1.3 14.7 11.8 32.5 1.9 60.6 9.0 6.8 31.6 9.6 4.3 3.2 386.3 72.8 155.0 73.0 31.5 30.9 72.1 181.2 88.8 206.0 176.8 94.4 209.7 236.6 101.9 81.1 140.0 212.5 183.0 95.0 332.4 297.9 113.8 234.7 123.3 33.6 17.3 158.3 182.6 14.6 13.3 114.4 96.5 78.5 94.8 103.2 130.3 272.2 133.9 78.3 183.2 44.4 91.8 106.7 149.3 180.1 238.8 177.3 43.4 54.8 93.7 94.0 141.4 135.1 65.5 76.6 156.9 128.6 84.8 132.2 105.2 119.9 349.8 181.1 192.2 412.0 96.7 166.9 151.9 74.4 6.0 23.6 11.5 8.9 11.4 17.2 18.2 14.3 6.6 15.0 11.4 10.2 10.8 15.3 15.9 11.7 30.3 9.5 1.0 2.0 1.2 1.7 0.9 1.9 1.7 1.4 1.6 1.3 1.9 3.2 24.6 105.8 174.0 3.9 43.7 40.8 18.2 33.1 30.7 14.9 21.5 21.0 41.3 25.8 35.0 35.0 8.4 74.6 54.4 41.4 3.9 20.9 48.6 35.2 27.0 44.8 30.1 305.8 3.5 14.7 138.1 50.7 32.6 36.1 79.1 77.3 38.2 20.4 61.3 0.0 2.9 44.5 24.4 29.7 43.5 28.3 25.1 36.4 17.8 17.8 39.3 9.3 46.4 3.5 30.1 13.5 26.5 48.2 95.9 14.1 25.9 8.6 25.4 25.8 131.5 21.7 73.2 339.8 239.4 58.1 35.7 34.1 58.4 34.6 69.7 19.1 SMC5 "KIAA0594, SMC5L1" ENSG00000198887 "Structural maintenance of chromosomes 5" Q8IY18 9 70258978-70354873 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054900 Supported Supported "Nuclear speckles" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "HPA054900: AB_2682634" "unprognostic (2.55e-1)" "unprognostic (1.82e-1)" "unprognostic (1.24e-2)" "unprognostic (1.40e-1)" "unprognostic (2.72e-1)" "unprognostic (8.04e-3)" "unprognostic (2.15e-2)" "unprognostic (1.20e-1)" "unprognostic (3.80e-2)" "unprognostic (2.23e-1)" "unprognostic (3.36e-2)" "unprognostic (7.30e-2)" "unprognostic (1.71e-2)" "unprognostic (2.73e-2)" "unprognostic (2.54e-1)" "unprognostic (1.62e-1)" "unprognostic (1.80e-1)" 10.2 7.7 4.3 15.0 4.8 26.0 16.6 10.4 5.0 12.2 9.0 15.0 13.5 15.2 12.8 10.8 12.3 12.9 9.9 4.2 6.1 8.0 14.8 12.8 18.5 5.2 5.7 25.2 19.4 10.4 9.6 14.8 5.7 11.4 16.9 8.3 17.1 8.7 13.8 9.0 13.9 10.7 4.2 12.0 14.5 13.5 4.9 18.2 14.3 8.2 16.1 16.4 11.3 7.8 43.9 10.8 26.6 16.2 15.1 28.3 20.9 29.8 25.8 15.9 17.3 4.1 23.3 43.7 9.5 22.5 13.9 39.3 28.9 19.8 31.7 19.9 10.3 25.5 18.3 13.1 19.2 41.8 25.3 19.9 13.5 21.5 24.5 25.4 16.9 25.8 19.1 17.1 29.9 6.7 55.4 14.7 20.4 33.5 14.9 32.4 43.6 13.7 16.1 21.3 18.9 14.2 29.5 18.7 8.3 19.2 11.2 17.6 18.6 21.3 22.4 29.2 41.2 20.9 29.9 29.9 17.9 21.6 25.9 14.1 5.6 10.4 8.5 6.3 8.0 8.4 7.3 8.1 4.6 8.2 8.0 7.4 3.7 8.1 7.6 8.7 8.4 4.0 4.3 4.8 10.4 5.0 4.2 6.1 5.2 5.7 5.7 4.2 4.9 7.8 48.9 57.7 70.3 61.7 54.6 45.6 102.0 30.3 59.7 26.8 39.2 34.0 34.6 41.5 62.0 20.2 29.2 32.1 65.2 38.8 9.8 61.3 47.9 65.3 58.9 37.6 28.1 29.0 72.2 54.8 37.5 62.1 40.8 89.1 51.8 52.5 16.1 25.9 16.4 38.7 66.4 34.8 20.3 22.9 30.8 15.9 53.4 37.9 24.9 74.0 65.4 17.2 54.6 85.5 94.6 68.3 37.9 59.5 40.6 105.5 23.6 11.7 51.0 35.7 26.3 66.2 52.2 80.0 55.0 52.5 41.9 35.6 56.7 58.4 45.0 105.8 SMIM19 C8orf40 ENSG00000176209 "Small integral membrane protein 19" Q96E16 8 42541155-42555195 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011145, HPA074830" Uncertain Approved "Nuclear speckles" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 2: Karpas-707 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" "HPA011145: AB_1078360, HPA074830: " "unprognostic (2.12e-2)" "unprognostic (2.33e-3)" "unprognostic (4.01e-2)" "unprognostic (1.85e-2)" "unprognostic (1.42e-1)" "unprognostic (6.68e-3)" "unprognostic (7.04e-3)" "unprognostic (1.76e-2)" "unprognostic (4.84e-2)" "unprognostic (1.74e-1)" "unprognostic (2.40e-1)" "unprognostic (2.67e-2)" "prognostic favorable (1.74e-6)" "unprognostic (5.10e-2)" "unprognostic (9.70e-3)" "unprognostic (9.64e-2)" "unprognostic (2.93e-3)" 55.2 57.1 34.7 18.4 35.4 32.5 64.9 35.8 44.3 31.9 35.8 41.7 30.0 32.6 80.0 33.2 57.0 27.8 59.6 36.1 35.8 76.9 136.8 31.5 36.9 34.2 34.9 42.2 68.5 36.2 26.8 23.3 35.1 31.9 34.6 21.1 62.6 30.1 121.8 44.8 38.9 25.1 35.7 33.3 46.2 43.9 35.0 36.6 73.5 74.1 33.9 36.4 29.9 37.3 38.9 28.5 61.0 52.6 35.9 43.2 19.9 29.9 40.2 23.4 27.8 6.8 84.4 42.4 12.2 25.1 57.0 27.2 31.8 19.2 24.3 33.8 26.3 35.9 17.9 15.5 73.9 25.7 9.0 35.4 16.1 19.6 62.7 45.3 21.5 49.1 28.8 94.5 23.7 38.0 18.8 39.0 72.1 90.4 19.5 21.1 43.4 72.4 60.7 28.5 12.7 46.0 30.0 32.2 93.1 32.6 68.0 48.2 27.3 14.7 12.5 40.8 19.6 88.7 53.8 56.9 62.2 40.9 39.6 92.2 42.3 31.4 46.3 34.0 56.5 71.3 59.6 57.0 65.1 68.3 55.6 54.3 15.3 80.7 28.8 107.2 78.2 40.0 34.7 35.4 35.8 44.3 36.1 35.8 34.2 34.9 35.1 35.7 35.0 37.3 53.1 22.4 45.9 5.9 43.0 45.8 63.5 89.8 70.6 25.2 89.9 108.8 75.7 88.6 66.2 33.1 6.2 90.1 58.6 36.2 201.5 67.9 183.9 109.6 26.0 43.9 16.3 45.6 12.7 126.8 62.9 65.5 43.3 54.8 40.0 52.3 47.8 142.5 78.3 23.5 13.4 74.4 61.1 45.9 51.0 77.5 69.0 47.3 92.5 11.2 64.0 66.7 42.2 10.6 14.6 85.5 69.5 59.5 29.0 53.3 161.9 228.2 110.9 14.3 26.3 67.6 50.7 131.3 48.6 58.4 49.6 47.2 43.3 76.4 74.8 63.2 SMTNL2 FLJ42461 ENSG00000188176 "Smoothelin like 2" Q2TAL5 17 4583999-4608319 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "skeletal muscle: 500.8;tongue: 136.2" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 8.7;Collecting duct cells: 9.2;Distal tubular cells: 33.2;Proximal tubular cells: 35.4;Sertoli cells: 26.3;Skeletal myocytes: 8.2" "Cancer enhanced" "Detected in many" "renal cancer: 10.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "CACO-2: 49.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA025706 Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 39: CACO-2 - Unknown function" "Cluster 37: Myocytes - Muscle contraction" "Nucleoplasm, Nuclear speckles" "HPA025706: AB_1848935" "unprognostic (8.62e-2)" "unprognostic (5.40e-2)" "unprognostic (7.13e-2)" "unprognostic (2.86e-1)" "unprognostic (1.05e-1)" "unprognostic (1.87e-2)" "unprognostic (4.89e-3)" "unprognostic (2.73e-1)" "unprognostic (3.73e-3)" "unprognostic (7.33e-2)" "unprognostic (1.55e-1)" "unprognostic (5.89e-2)" "prognostic favorable (1.28e-4)" "unprognostic (3.43e-2)" "unprognostic (1.01e-1)" "unprognostic (1.56e-3)" "unprognostic (2.22e-1)" 8.3 0.1 0.9 1.5 1.1 0.0 2.5 0.8 1.6 3.4 1.0 1.2 0.2 3.9 2.3 8.0 7.2 2.1 18.2 2.5 0.7 31.8 0.2 4.7 0.2 0.9 1.0 6.7 0.6 1.1 2.3 4.9 1.0 5.0 0.5 0.1 6.1 0.9 500.8 1.5 1.2 2.5 0.7 0.8 1.0 1.3 1.0 0.2 1.4 136.2 0.1 4.5 2.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 49.5 0.0 0.0 0.4 0.0 0.8 0.0 2.7 0.0 0.6 0.0 2.9 0.0 0.0 5.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.0 1.3 3.2 0.0 0.0 0.0 0.1 5.4 0.0 11.4 0.0 0.0 0.0 0.0 10.1 0.0 1.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.1 0.8 1.6 2.5 0.7 0.9 1.0 1.0 0.7 1.0 0.8 0.3 0.0 1.1 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.1 0.0 8.7 0.0 0.6 9.2 0.0 0.8 0.0 0.0 33.2 0.1 0.1 1.8 1.3 1.3 0.0 0.0 0.1 0.0 1.5 6.1 0.0 2.0 0.0 0.1 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.3 0.3 0.6 0.3 1.8 1.9 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 35.4 0.0 0.0 26.3 8.2 7.6 0.0 0.5 0.1 0.0 0.5 0.3 0.1 0.2 0.3 SMURF2 ENSG00000108854 "SMAD specific E3 ubiquitin protein ligase 2" Q9HAU4 17 64542282-64662307 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BJ: 221.1;HBF TERT88: 157.4;LHCN-M2: 164.1;TIME: 207.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071508 Enhanced Supported "Nuclear speckles" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nuclear speckles" "HPA071508: AB_2686406" "unprognostic (1.21e-1)" "unprognostic (2.07e-2)" "unprognostic (1.59e-2)" "unprognostic (3.24e-1)" "unprognostic (6.19e-2)" "unprognostic (7.33e-2)" "unprognostic (2.67e-2)" "unprognostic (1.50e-1)" "unprognostic (7.94e-2)" "unprognostic (1.09e-2)" "unprognostic (5.46e-3)" "unprognostic (2.54e-1)" "unprognostic (5.55e-2)" "unprognostic (1.98e-2)" "unprognostic (7.82e-2)" "unprognostic (2.20e-2)" "unprognostic (1.41e-1)" 6.8 4.3 3.3 6.2 3.9 5.9 5.2 5.3 3.4 7.3 3.4 5.3 6.9 5.9 2.3 4.4 5.8 7.1 4.1 3.1 3.3 7.0 3.8 10.5 5.0 4.6 2.7 4.8 6.5 6.3 3.4 13.3 2.8 7.4 4.8 12.5 6.2 5.2 3.0 5.0 10.1 6.1 3.2 5.4 7.8 13.0 3.6 7.8 8.3 6.2 6.5 7.5 3.2 3.8 67.0 17.8 15.3 9.1 11.0 41.5 7.6 221.1 103.2 88.2 73.4 10.4 45.5 8.6 14.5 38.8 29.9 15.2 16.0 37.2 157.4 4.3 12.9 9.1 10.9 11.8 12.0 12.2 5.5 11.8 16.1 109.5 48.5 52.7 97.0 11.9 13.0 7.5 164.1 13.2 28.3 4.8 9.9 8.8 23.8 6.1 38.4 5.2 20.1 11.1 16.0 17.9 14.4 5.8 10.0 24.6 11.7 8.4 207.6 93.8 44.4 39.2 139.6 10.4 11.7 13.9 23.7 7.3 28.4 1.0 0.6 1.4 1.0 0.4 1.1 0.7 0.8 1.1 0.7 0.9 0.9 0.9 1.4 2.7 0.3 0.6 0.2 0.5 3.3 3.9 5.3 3.4 3.1 3.3 4.6 2.7 2.8 3.2 3.6 3.8 40.2 32.1 26.0 96.3 18.6 43.8 30.8 10.0 25.0 26.4 23.3 18.7 10.3 7.2 16.1 9.2 43.8 13.2 35.4 13.8 9.8 18.1 29.0 29.0 37.2 39.3 17.9 2.5 46.1 10.0 3.6 28.1 12.2 39.7 13.3 21.4 38.2 5.1 13.6 26.9 40.9 11.2 10.2 17.3 25.5 9.2 12.5 22.8 21.4 101.2 13.2 21.4 20.6 101.0 52.8 26.5 24.7 12.0 18.0 25.2 28.0 9.6 14.4 46.7 0.0 37.4 23.3 37.1 21.3 13.7 39.8 7.3 33.5 16.2 13.8 24.6 SNRNP40 "HPRP8BP, PRP8BP, PRPF8BP, SPF38, WDR57" ENSG00000060688 "Small nuclear ribonucleoprotein U5 subunit 40" Q96DI7 1 31259568-31296788 "Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026527, HPA027345" Supported Supported "Nuclear speckles" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear speckles" "HPA026527: AB_1858814, HPA027345: AB_2239703" "unprognostic (2.31e-3)" "unprognostic (5.63e-2)" "unprognostic (5.24e-3)" "unprognostic (1.36e-1)" "unprognostic (1.14e-3)" "unprognostic (1.28e-2)" "prognostic unfavorable (4.73e-6)" "unprognostic (2.14e-2)" "unprognostic (2.43e-2)" "unprognostic (2.50e-1)" "unprognostic (1.22e-1)" "unprognostic (8.57e-2)" "unprognostic (2.34e-2)" "unprognostic (1.78e-2)" "unprognostic (5.93e-2)" "unprognostic (4.31e-2)" "unprognostic (6.24e-2)" 17.9 18.9 10.7 21.2 14.6 30.0 20.7 15.5 12.6 17.7 10.3 20.6 16.4 20.1 21.7 19.1 22.5 13.1 14.2 10.4 12.5 17.6 19.3 15.8 35.4 14.5 13.3 20.8 13.0 18.0 15.9 22.3 15.4 20.1 22.1 19.1 15.0 20.8 20.9 18.5 17.6 21.7 13.7 21.3 16.6 21.2 12.8 40.3 18.0 18.1 40.2 24.0 16.7 20.1 71.6 53.6 95.5 78.6 46.7 38.4 66.2 58.8 57.4 104.7 101.9 76.7 69.8 91.8 56.4 46.1 53.9 66.4 145.7 69.8 105.9 99.2 109.3 135.2 72.1 83.9 58.4 150.0 59.3 36.2 54.7 102.1 75.6 34.4 86.1 80.2 129.0 52.9 60.5 51.6 111.3 87.9 171.6 71.1 76.5 87.3 134.5 71.1 44.2 57.7 65.1 63.6 92.3 47.4 116.2 88.0 47.2 94.9 59.5 57.9 85.2 81.5 112.9 43.5 57.1 126.1 47.1 139.3 96.4 102.8 75.8 82.3 98.6 97.3 113.1 93.8 95.1 98.2 93.0 82.6 101.1 115.1 16.4 110.5 92.0 78.4 110.2 161.1 10.7 14.6 15.5 12.6 10.4 12.5 14.5 13.3 15.4 13.7 12.8 20.1 44.1 3.2 6.1 14.7 51.5 53.0 50.2 90.8 41.5 15.6 24.4 30.6 16.5 21.5 32.5 16.5 18.8 108.7 35.7 11.9 43.0 42.5 7.1 21.0 27.5 39.4 34.8 80.8 23.7 35.9 91.3 38.1 28.5 13.9 34.3 36.2 28.9 22.3 56.2 10.1 24.3 18.6 69.2 20.7 48.6 5.4 26.8 31.5 42.7 15.0 44.7 23.8 44.3 23.6 49.0 36.4 20.2 34.3 40.6 55.0 17.0 45.0 27.6 22.2 32.9 31.0 35.1 105.5 89.7 39.6 54.8 61.3 52.4 45.9 36.9 40.6 SNRPA1 "Lea1, U2A'" ENSG00000131876 "Small nuclear ribonucleoprotein polypeptide A'" P09661 15 101281510-101295282 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045622, HPA048499" Supported Supported "Nucleoplasm,Nuclear speckles,Nuclear bodies" NA NA 48000 "Cluster 39: Non-specific - mRNA processing" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Nuclear speckles, Nuclear bodies" "HPA045622: AB_2679394, HPA048499: AB_2680421" "unprognostic (2.73e-1)" "unprognostic (1.48e-1)" "unprognostic (8.09e-2)" "unprognostic (2.20e-1)" "unprognostic (8.08e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (8.56e-5)" "unprognostic (5.80e-2)" "unprognostic (1.66e-3)" "prognostic favorable (8.83e-5)" "unprognostic (4.74e-2)" "unprognostic (6.77e-3)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.06e-2)" "unprognostic (2.84e-1)" "unprognostic (2.43e-1)" "unprognostic (1.37e-2)" 19.0 18.2 11.0 35.5 11.4 68.1 20.8 13.2 15.4 14.7 14.7 30.6 24.3 15.5 33.0 33.8 18.6 12.7 25.8 12.0 11.6 25.2 25.5 19.5 43.3 11.5 11.3 13.6 22.2 18.3 13.9 30.4 11.7 16.3 30.8 15.5 23.1 12.6 19.7 18.5 30.1 19.3 10.9 25.2 23.2 37.8 12.4 37.4 18.3 12.4 51.9 26.3 18.2 12.6 175.5 119.5 112.7 57.4 31.3 25.6 111.3 158.2 72.8 139.2 105.1 255.8 150.7 192.9 89.2 107.8 109.0 101.7 170.2 113.1 148.1 98.0 262.5 151.4 196.7 137.3 24.0 175.1 103.7 21.0 83.0 89.0 111.3 30.9 90.9 147.1 216.1 175.8 86.5 194.6 177.6 185.7 144.5 232.0 100.1 174.5 121.7 194.8 103.3 450.2 88.6 92.7 97.2 109.0 125.1 117.1 105.2 136.4 66.2 74.1 141.0 86.8 160.3 143.5 464.8 378.9 59.9 162.9 89.3 3.8 36.6 21.5 55.7 47.2 55.3 53.0 57.7 56.1 58.0 47.4 46.6 59.0 6.8 48.5 44.0 54.7 68.9 39.0 11.0 11.4 13.2 15.4 12.0 11.6 11.5 11.3 11.7 10.9 12.4 12.6 41.5 19.2 54.6 16.3 71.6 65.6 73.4 141.6 70.6 37.8 41.8 52.6 30.5 18.6 80.3 36.8 12.5 124.3 69.6 37.4 68.4 94.6 96.2 52.7 42.5 47.2 27.0 61.4 30.9 109.0 154.1 51.5 27.0 55.6 65.8 37.7 21.4 35.5 67.0 37.0 29.2 44.2 126.1 24.1 39.2 22.4 34.8 36.4 42.7 13.1 76.4 39.6 47.4 16.6 28.6 95.3 41.8 28.6 76.1 142.3 78.7 87.1 89.2 34.9 13.1 37.9 67.1 192.9 65.9 68.3 50.6 112.3 68.1 42.3 52.4 101.6 SNRPB2 "Msl1, U2B''" ENSG00000125870 "Small nuclear ribonucleoprotein polypeptide B2" P08579 20 16729961-16742564 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 524.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 381.4;SK-MEL-30: 378.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050814, HPA076104" Supported Supported "Nuclear speckles,Cytoplasmic bodies" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles" "Cytoplasmic bodies" "HPA050814: AB_2681245, HPA076104: AB_2732301" "unprognostic (4.73e-2)" "unprognostic (1.78e-1)" "unprognostic (4.02e-1)" "prognostic unfavorable (7.57e-4)" "unprognostic (8.45e-2)" "unprognostic (8.36e-2)" "prognostic unfavorable (6.03e-7)" "unprognostic (4.23e-2)" "unprognostic (5.94e-2)" "unprognostic (1.65e-2)" "unprognostic (2.73e-2)" "unprognostic (4.06e-1)" "prognostic unfavorable (2.79e-4)" "unprognostic (1.21e-1)" "unprognostic (1.78e-1)" "unprognostic (1.14e-2)" "unprognostic (1.77e-1)" 27.5 27.6 23.9 30.9 24.9 53.9 31.0 24.3 35.7 22.3 26.0 26.4 24.3 29.0 35.2 20.8 24.4 21.9 25.0 24.9 25.9 42.3 30.1 22.2 43.3 24.9 25.2 29.1 18.3 26.9 22.6 28.7 24.7 21.9 26.5 11.2 21.1 21.6 30.2 17.0 24.6 27.1 25.6 28.4 23.4 22.6 24.7 37.3 25.6 27.2 36.6 28.9 19.8 27.3 76.0 73.3 94.3 59.1 46.1 57.8 104.7 73.4 60.9 78.0 76.1 84.6 83.5 121.0 56.0 63.0 119.2 69.3 74.9 85.5 111.0 40.0 62.8 111.8 22.4 157.4 53.9 132.0 73.8 57.6 56.0 71.5 55.6 58.1 74.4 81.3 93.8 53.6 80.6 79.2 152.5 159.6 84.2 381.4 97.0 86.1 113.1 84.9 76.9 50.8 49.8 142.3 54.5 147.6 378.7 69.4 93.8 106.5 63.7 71.0 71.2 64.4 122.7 46.9 102.8 134.7 33.7 77.8 157.1 51.8 29.4 47.4 27.3 38.6 35.8 31.5 34.7 31.5 31.6 29.1 30.0 33.4 12.8 31.7 40.5 45.9 48.0 29.9 23.9 24.9 24.3 35.7 24.9 25.9 24.9 25.2 24.7 25.6 24.7 27.3 125.9 44.8 58.0 6.2 128.6 89.1 186.9 238.2 60.3 30.7 93.8 118.5 67.4 107.2 126.5 93.8 0.0 281.4 150.1 79.6 215.2 165.9 163.3 105.3 150.3 124.6 93.3 131.7 12.9 169.2 288.3 120.8 50.0 120.5 132.5 103.2 140.3 139.3 227.3 48.8 14.3 133.3 152.5 157.9 124.6 35.1 172.7 120.5 110.3 8.4 195.4 77.7 153.5 15.1 21.5 169.4 102.7 155.7 91.2 143.8 94.9 524.6 107.2 25.1 98.6 118.7 147.5 192.4 130.4 60.8 96.0 376.9 150.1 94.7 127.7 170.2 SNURF ENSG00000273173 "SNRPN upstream reading frame" Q9Y675 15 24954986-24977850 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 62.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NTERA-2: 191.3;U-698: 112.1" HPA065733 Supported "Nuclear speckles" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 59: Non-specific - Transcription" "Nuclear speckles" "HPA065733: AB_2685548" "unprognostic (2.08e-1)" "unprognostic (2.88e-2)" "unprognostic (6.82e-2)" "unprognostic (4.59e-3)" "unprognostic (4.03e-2)" "unprognostic (1.40e-3)" "unprognostic (4.39e-2)" "unprognostic (6.89e-3)" "unprognostic (1.56e-2)" "unprognostic (6.74e-2)" "unprognostic (8.91e-4)" "unprognostic (3.77e-1)" "unprognostic (1.77e-2)" "unprognostic (6.04e-2)" "unprognostic (1.06e-1)" "unprognostic (1.45e-1)" "unprognostic (1.12e-2)" 8.1 16.1 3.7 6.9 7.5 12.5 5.3 16.3 16.0 12.1 1.2 14.6 1.9 9.6 54.8 5.3 8.5 13.2 50.7 5.6 11.8 14.6 12.9 9.8 10.2 1.5 2.8 13.7 13.5 19.8 28.5 2.7 2.4 15.2 2.5 25.3 8.4 8.3 62.9 3.7 6.4 3.8 0.5 17.2 11.5 3.3 6.5 8.1 15.5 7.4 7.0 12.8 7.3 8.6 0.1 11.9 61.9 44.1 3.1 4.1 0.1 40.7 3.3 4.2 2.8 7.0 36.4 0.5 21.0 2.7 6.0 15.3 0.0 9.1 3.2 14.1 0.0 74.3 50.2 1.8 11.0 79.2 25.4 10.0 2.3 7.7 0.5 22.1 5.2 22.4 7.3 0.2 8.3 0.0 55.5 0.5 191.3 0.0 1.9 54.7 84.7 0.9 3.3 82.0 37.1 29.1 0.0 3.8 22.3 75.2 38.7 7.1 75.8 27.2 30.2 1.0 8.9 58.8 81.6 112.1 43.9 33.6 24.5 17.7 1.5 6.3 14.9 0.7 31.0 22.3 32.9 28.4 2.7 27.8 41.2 38.1 1.7 22.4 3.1 23.6 35.7 20.1 3.7 7.5 16.3 16.0 5.6 11.8 1.5 2.8 2.4 0.5 6.5 8.6 1.0 3.2 3.7 0.0 2.9 0.5 0.6 1.4 2.2 1.6 1.4 1.1 4.1 0.0 1.1 0.0 0.0 0.0 1.1 0.7 3.9 2.1 0.4 0.7 1.2 0.9 0.0 0.8 0.0 2.4 0.0 1.4 1.5 0.7 1.3 2.0 1.1 0.7 0.3 3.3 0.0 2.7 0.0 0.8 0.4 0.3 0.6 0.6 0.0 0.0 0.7 0.4 0.0 0.0 0.0 2.2 2.8 0.4 2.7 0.6 1.1 0.7 4.1 1.5 0.0 0.9 2.0 0.3 0.8 0.7 0.3 0.0 2.8 1.9 1.2 0.3 SOCS6 "CIS4, Cish4, HSPC060, SOCS4, SSI4, STAI4, STATI4" ENSG00000170677 "Suppressor of cytokine signaling 6" O14544 18 70289045-70330199 "Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 86.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 3.6;myeloid DC: 3.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010189 Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear speckles" Cytosol "CAB010189: AB_661195" "unprognostic (1.76e-3)" "unprognostic (6.83e-3)" "unprognostic (8.90e-3)" "unprognostic (4.52e-2)" "unprognostic (1.01e-1)" "unprognostic (2.07e-1)" "unprognostic (2.07e-1)" "unprognostic (7.93e-2)" "unprognostic (5.83e-2)" "unprognostic (1.75e-1)" "unprognostic (6.90e-2)" "unprognostic (8.19e-2)" "prognostic favorable (1.02e-4)" "unprognostic (1.02e-1)" "unprognostic (1.52e-1)" "unprognostic (4.11e-2)" "unprognostic (1.80e-2)" 7.9 8.0 8.3 6.0 10.2 13.1 14.0 11.7 8.1 15.2 5.8 16.2 15.6 11.8 6.9 15.0 12.3 13.5 11.0 7.8 7.6 9.3 28.3 9.7 3.4 14.8 10.2 10.9 13.0 14.1 4.1 13.9 14.4 8.4 14.4 5.6 11.3 7.9 12.8 7.1 22.8 10.9 13.2 4.1 14.0 5.7 17.5 3.2 11.6 13.4 5.6 8.3 8.0 19.3 19.2 41.6 17.4 12.0 16.1 18.9 19.4 40.3 24.5 24.0 18.0 15.6 31.7 2.1 3.6 37.7 29.0 22.2 12.8 13.2 23.3 0.0 7.8 14.4 14.3 24.1 19.1 7.9 15.6 15.3 15.4 20.9 17.4 23.9 12.2 1.7 8.7 9.6 16.5 9.3 6.8 5.8 11.2 12.2 17.7 8.0 16.8 3.5 14.9 15.6 8.0 20.0 20.9 22.8 18.9 12.4 6.8 13.6 15.1 26.3 13.3 5.5 16.5 0.0 0.0 5.2 29.3 0.6 18.1 0.0 3.6 2.9 0.2 0.7 0.1 0.3 0.4 0.0 3.9 0.0 0.6 0.3 0.0 1.0 0.0 0.3 0.0 1.2 8.3 10.2 11.7 8.1 7.8 7.6 14.8 10.2 14.4 13.2 17.5 19.3 15.0 25.6 17.0 8.1 1.2 11.7 13.7 13.3 12.0 12.9 26.6 14.7 22.4 21.5 30.1 11.0 6.2 28.0 2.1 61.0 11.7 18.4 1.3 23.5 23.5 13.9 29.4 3.8 17.0 18.5 15.6 13.7 21.4 34.6 31.0 9.1 13.6 32.4 25.7 37.0 17.5 31.0 10.2 7.7 11.1 2.8 11.5 19.2 26.6 86.2 10.1 7.8 5.2 28.6 32.1 30.5 30.5 12.8 0.9 17.4 36.8 25.6 21.8 4.7 0.0 14.9 12.5 1.3 11.0 20.5 11.9 68.4 2.1 4.4 26.7 34.6 SOHLH1 "bA100C15.3, bHLHe80, C9orf157, NOHLH, SPATA27, TEB2" ENSG00000165643 "Spermatogenesis and oogenesis specific basic helix-loop-helix 1" Q5JUK2 9 135693407-135704498 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 28.9;choroid plexus: 13.1;testis: 16.9" "Cell type enriched" "Detected in some" 4 "Spermatogonia: 78.3" "Group enriched" "Detected in some" 5 "cervical cancer: 2.3;endometrial cancer: 0.6;head and neck cancer: 2.3;lung cancer: 2.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "CACO-2: 20.9;U-266/84: 39.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA059439 Approved "Nuclear speckles" NA NA "Cluster 65: Brain - Ion transport" "Cluster 16: U-266 - Nucleosome" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nuclear speckles" "HPA059439: AB_2684017" "unprognostic (2.93e-1)" "unprognostic (1.23e-3)" "unprognostic (9.85e-3)" "unprognostic (2.84e-2)" "unprognostic (3.55e-1)" "unprognostic (2.59e-3)" "unprognostic (4.98e-3)" "unprognostic (2.17e-1)" "unprognostic (1.63e-1)" 0.1 0.0 15.5 0.0 17.0 0.0 0.0 13.9 28.9 0.0 13.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 16.3 13.7 0.0 0.0 0.0 0.0 17.8 13.7 0.1 0.0 0.1 3.2 0.0 17.8 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 13.5 0.1 0.1 16.9 13.5 0.0 0.0 0.0 0.0 0.0 0.0 19.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 20.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 39.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.5 17.0 13.9 28.9 16.3 13.7 17.8 13.7 17.8 13.5 13.5 19.3 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.1 0.0 0.0 15.9 0.2 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.5 0.0 0.0 0.0 0.0 5.1 0.6 0.0 0.0 3.7 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.5 78.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 SON "BASS1, C21orf50, DBP-5, FLJ21099, FLJ33914, KIAA1019, NREBP" ENSG00000159140 "SON DNA and RNA binding protein" P18583 21 33543038-33577481 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell cycle, mRNA processing, mRNA splicing" "DNA-binding, RNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023535, HPA031755, HPA031756" Supported Enhanced "Nuclear speckles" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nuclear speckles" "HPA023535: AB_1857362, HPA031755: AB_2674029, HPA031756: AB_2674030" "unprognostic (1.58e-2)" "unprognostic (2.08e-1)" "unprognostic (4.69e-1)" "unprognostic (2.30e-1)" "unprognostic (5.63e-2)" "unprognostic (2.75e-1)" "unprognostic (4.22e-2)" "unprognostic (2.38e-1)" "unprognostic (1.05e-1)" "unprognostic (2.31e-2)" "unprognostic (2.02e-1)" "unprognostic (1.24e-1)" "unprognostic (9.75e-2)" "unprognostic (4.18e-1)" "unprognostic (9.20e-2)" "unprognostic (1.19e-1)" "unprognostic (2.54e-1)" 69.1 62.5 45.6 57.8 52.1 161.9 65.0 56.4 58.6 59.4 71.9 64.1 44.9 66.9 61.5 60.7 68.5 43.2 60.3 43.7 45.7 49.4 60.3 65.2 81.0 49.8 46.8 76.7 63.4 92.8 63.9 60.9 51.3 61.2 56.4 91.8 64.3 52.6 89.4 64.1 67.8 51.1 47.6 71.5 66.8 48.0 47.8 92.8 64.4 53.8 76.2 62.9 55.9 65.8 105.7 59.7 126.1 72.7 108.1 98.3 89.2 77.2 88.1 73.0 69.6 89.5 75.2 163.8 45.9 114.8 86.6 76.4 152.4 113.0 109.7 85.4 77.9 220.0 78.2 111.3 79.3 215.0 110.8 100.6 128.7 88.0 124.5 91.3 110.1 91.2 172.9 150.9 101.1 101.6 121.0 112.9 136.0 108.5 60.7 121.5 133.8 118.1 109.7 102.1 84.1 77.6 124.2 100.3 91.3 103.6 93.6 128.3 116.0 83.4 73.1 66.6 87.0 144.8 143.2 193.9 84.7 172.3 78.9 33.7 20.3 28.7 20.7 18.4 20.8 30.4 22.9 22.1 15.8 28.2 22.7 22.3 37.4 22.3 24.5 38.5 22.1 15.8 45.6 52.1 56.4 58.6 43.7 45.7 49.8 46.8 51.3 47.6 47.8 65.8 374.1 410.3 298.2 201.4 355.2 433.1 312.2 310.6 250.4 389.7 213.1 219.2 351.5 320.3 298.0 301.6 221.0 224.1 423.2 276.8 193.7 209.7 97.0 296.9 412.2 342.1 186.8 375.8 93.1 207.3 164.7 333.4 208.0 335.8 418.2 216.1 304.8 344.6 170.1 455.9 105.8 256.0 219.7 237.2 307.4 66.0 393.9 261.0 218.7 146.1 256.8 335.7 347.1 131.7 162.3 190.0 217.2 393.4 294.4 250.7 198.0 225.7 288.3 372.0 381.3 505.0 399.2 470.1 334.6 197.8 394.2 327.1 378.2 183.2 246.3 226.5 SOX7 ENSG00000171056 "SRY-box transcription factor 7" Q9BT81 8 10723768-10730511 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "vagina: 42.4" "Cell type enhanced" "Detected in many" "Adipocytes: 115.4;Basal keratinocytes: 61.2;Basal prostatic cells: 67.6;Basal squamous epithelial cells: 148.5;Endothelial cells: 115.1;Squamous epithelial cells: 98.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 11.8;hTCEpi: 21.3;HUVEC TERT2: 25.2;TIME: 6.8" "Low region specificity" "Detected in many" HPA009065 Approved Approved "Nuclear speckles,Golgi apparatus" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles" "Golgi apparatus" "HPA009065: AB_1857390" "unprognostic (1.21e-1)" "unprognostic (1.08e-1)" "unprognostic (1.15e-3)" "unprognostic (1.29e-2)" "unprognostic (1.60e-1)" "unprognostic (1.65e-1)" "unprognostic (3.17e-2)" "unprognostic (1.02e-1)" "unprognostic (8.74e-2)" "unprognostic (7.26e-2)" "unprognostic (7.44e-2)" "unprognostic (1.09e-1)" "unprognostic (7.71e-3)" "unprognostic (2.45e-3)" "unprognostic (2.38e-1)" "unprognostic (5.41e-3)" "unprognostic (4.84e-3)" 22.6 3.8 2.5 1.0 2.3 0.1 11.9 1.9 2.6 27.0 1.4 4.2 0.1 4.3 1.1 26.8 4.5 3.6 18.5 2.1 1.8 5.1 4.3 23.2 1.7 2.6 2.2 1.5 2.6 1.0 5.6 17.3 2.5 5.4 1.1 0.4 10.5 2.7 9.8 20.2 3.6 2.3 2.5 2.4 3.7 0.7 2.7 1.5 7.6 6.4 1.9 4.6 42.4 2.0 5.8 0.1 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.4 0.3 0.6 11.8 3.4 4.2 0.1 0.1 0.4 0.1 0.3 0.1 0.0 0.2 0.2 0.1 21.3 0.0 4.3 0.0 25.2 0.0 0.6 0.3 0.0 0.2 0.2 0.2 1.6 0.9 3.2 1.2 0.0 0.0 0.0 2.1 0.6 3.4 2.2 0.0 0.0 1.4 0.0 0.1 6.8 0.1 0.0 0.1 0.1 0.0 0.3 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 2.3 1.9 2.6 2.1 1.8 2.6 2.2 2.5 2.5 2.7 2.0 115.4 0.0 11.5 0.3 1.1 61.2 67.6 24.5 148.5 1.2 5.2 4.7 4.8 1.5 6.3 0.0 4.2 4.3 0.1 0.2 0.0 0.2 0.2 14.9 1.9 115.1 0.0 0.0 4.6 0.2 0.8 4.7 0.0 22.9 3.8 0.5 48.5 4.9 0.7 0.0 2.9 0.2 10.2 1.9 8.7 0.1 0.9 0.9 3.6 10.3 0.3 0.5 0.0 1.5 0.8 0.5 0.0 0.4 1.2 17.8 0.1 0.6 3.2 2.2 0.0 8.5 4.4 2.4 1.6 98.9 40.6 12.4 1.8 1.2 0.4 26.6 SPATA45 "C1orf227, LOC149643" ENSG00000185523 "Spermatogenesis associated 45" Q537H7 1 212830141-212847649 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 8 "pancreas: 2.9;testis: 11.8" "Group enriched" "Detected in some" 24 "Early spermatids: 151.6;Late spermatids: 139.9" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 1.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "U-698: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA049921 Uncertain Approved "Nuclear speckles,Cytosol" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" "Nuclear speckles, Cytosol" "HPA049921: AB_2680953" "unprognostic (1.17e-1)" "unprognostic (2.83e-2)" "unprognostic (4.71e-1)" "unprognostic (2.06e-1)" "unprognostic (4.05e-2)" "unprognostic (6.14e-2)" "unprognostic (4.39e-4)" "unprognostic (1.07e-2)" "unprognostic (1.70e-1)" "unprognostic (3.12e-3)" "unprognostic (1.64e-2)" "unprognostic (3.14e-1)" "unprognostic (2.06e-2)" "unprognostic (6.14e-3)" "unprognostic (1.32e-2)" "unprognostic (9.50e-2)" "unprognostic (2.67e-3)" 0.2 0.1 0.3 0.1 0.5 0.3 0.3 0.4 0.9 0.1 0.0 0.3 0.1 0.3 0.7 0.2 0.7 0.4 0.1 0.2 0.4 0.3 0.4 0.4 0.8 0.7 0.4 0.1 2.9 0.1 0.3 0.3 0.5 0.3 0.1 0.6 0.0 0.0 0.2 0.0 0.2 0.5 0.5 0.5 0.2 11.8 0.6 0.1 0.4 0.5 0.4 0.2 0.0 0.7 0.1 1.5 0.3 0.9 0.2 0.7 0.9 0.1 0.0 0.3 0.4 0.3 0.2 0.3 0.0 0.0 0.6 0.1 0.6 0.0 0.3 1.4 0.0 0.0 0.0 0.8 0.4 0.0 0.6 0.5 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.6 0.8 0.9 0.1 0.3 0.2 0.3 0.5 0.8 0.1 0.0 0.7 0.1 0.3 1.0 0.6 0.0 0.0 0.3 0.2 0.5 0.0 0.3 0.0 0.7 0.4 0.4 0.7 1.7 0.1 0.6 0.4 0.0 0.1 1.6 0.2 0.3 0.3 0.1 0.0 0.0 0.2 1.1 0.2 0.3 0.8 0.1 0.2 0.0 0.1 0.1 0.3 0.5 0.4 0.9 0.2 0.4 0.7 0.4 0.5 0.5 0.6 0.7 0.2 0.0 0.0 0.7 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.1 0.0 5.9 0.0 151.6 0.1 0.0 0.2 0.0 0.0 0.9 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.3 0.3 0.0 1.3 0.0 0.0 0.0 0.0 139.9 1.5 0.2 0.0 1.0 0.6 0.0 0.0 1.0 2.1 0.1 0.0 0.4 0.0 0.0 0.8 0.3 1.5 0.0 0.0 0.0 0.1 1.5 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 SPINDOC "C11orf84, SPIN-DOC" ENSG00000168005 "Spindlin interactor and repressor of chromatin binding" Q9BUA3 11 63813456-63827716 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 7.2;Breast glandular cells: 6.7;Breast myoepithelial cells: 8.6;Cytotrophoblasts: 13.3;dendritic cells: 9.4;Endometrial stromal cells: 8.0;Granulosa cells: 9.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040128, HPA050313" Uncertain Approved "Nuclear speckles" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 24: NB-4 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Nuclear speckles" "HPA040128: AB_10673027, HPA050313: AB_2681083" "unprognostic (2.05e-2)" "unprognostic (1.35e-1)" "unprognostic (1.52e-2)" "unprognostic (2.82e-3)" "unprognostic (1.13e-1)" "unprognostic (1.75e-2)" "prognostic unfavorable (1.53e-5)" "unprognostic (2.20e-1)" "unprognostic (3.78e-3)" "unprognostic (1.44e-2)" "unprognostic (1.20e-2)" "unprognostic (4.33e-2)" "prognostic unfavorable (5.42e-5)" "unprognostic (2.54e-2)" "unprognostic (1.26e-1)" "unprognostic (7.23e-2)" "unprognostic (1.25e-1)" 11.9 10.4 25.8 12.1 26.3 6.2 8.9 27.9 38.1 16.3 20.7 19.2 5.4 19.1 5.1 10.1 15.3 9.3 15.8 26.0 31.5 13.8 5.2 16.4 15.0 25.4 26.4 16.6 8.0 3.3 17.3 26.4 27.9 18.2 3.6 9.8 9.0 10.4 8.0 6.0 11.3 8.2 22.9 13.9 11.4 38.8 31.4 12.3 13.4 7.2 9.8 18.0 12.3 25.8 34.9 45.7 65.7 57.6 12.5 12.3 24.7 26.6 22.7 47.4 32.9 48.7 23.4 58.1 60.6 15.5 60.8 44.9 60.3 13.7 17.1 55.6 26.4 64.2 46.4 42.0 20.1 36.4 53.6 14.2 14.1 37.2 13.6 24.9 28.5 54.8 36.1 27.6 20.2 48.0 75.7 98.2 112.9 10.0 42.1 100.3 45.5 19.7 16.5 20.2 50.0 63.2 40.6 25.6 55.3 39.7 35.3 43.0 32.2 52.9 60.8 64.0 47.3 40.1 61.9 58.2 27.3 31.8 38.1 0.5 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.3 0.1 0.0 25.8 26.3 27.9 38.1 26.0 31.5 25.4 26.4 27.9 22.9 31.4 25.8 7.2 3.2 1.5 0.0 2.0 0.0 0.0 0.0 0.0 0.0 6.7 8.6 0.0 0.0 0.6 0.0 0.0 13.3 9.4 0.0 0.0 2.2 0.0 5.6 8.0 3.1 0.0 0.0 0.0 1.8 3.0 2.7 0.0 6.5 0.0 9.6 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 2.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 1.4 0.0 0.0 0.7 0.7 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 3.8 2.8 4.0 0.0 0.0 SPTSSB "ADMP, C3orf57, ssSPTb" ENSG00000196542 "Serine palmitoyltransferase small subunit B" Q8NFR3 3 161344792-161372880 "Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 45.5;stomach 1: 61.4;urinary bladder: 49.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 28.5;Exocrine glandular cells: 46.0;Gastric mucus-secreting cells: 37.2;Melanocytes: 46.2;Prostatic glandular cells: 74.6;Suprabasal keratinocytes: 36.4;Urothelial cells: 65.6" "Cancer enhanced" "Detected in many" "urothelial cancer: 24.0" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 13 "NK-cell: 353.6" "Lineage enriched" "Detected in many" 13 "NK-cells: 353.6" "Group enriched" "Detected in some" 10 "MCF7: 1167.1;RT4: 304.2" HPA047712 Uncertain "Nuclear speckles" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 35: Glandular cells - Unknown function" "Nuclear speckles" "HPA047712: AB_2680127" "unprognostic (2.09e-1)" "unprognostic (4.19e-2)" "unprognostic (1.30e-1)" "unprognostic (1.24e-1)" "unprognostic (1.34e-2)" "unprognostic (4.15e-2)" "unprognostic (3.18e-2)" "unprognostic (1.98e-1)" "unprognostic (5.10e-2)" "unprognostic (6.37e-3)" "unprognostic (2.72e-1)" "unprognostic (4.08e-2)" "unprognostic (5.37e-4)" "unprognostic (8.21e-2)" "unprognostic (1.99e-1)" "unprognostic (1.22e-2)" "unprognostic (9.51e-3)" 1.9 0.1 3.7 0.6 1.9 0.3 8.3 5.2 7.9 4.8 3.0 0.8 0.3 1.0 0.1 8.7 0.4 1.3 0.4 2.2 1.3 1.2 0.5 0.1 1.2 2.8 5.6 0.2 0.8 0.1 0.4 0.0 4.8 14.7 0.7 2.5 11.4 0.1 0.1 45.5 0.3 0.2 0.2 1.3 61.4 0.0 6.7 0.4 0.3 1.5 2.0 49.5 11.1 3.7 0.0 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 2.9 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.4 0.0 0.0 0.1 0.1 2.0 0.1 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1167.1 0.0 0.0 4.3 71.5 13.4 0.0 0.0 0.5 0.0 304.2 1.9 11.9 0.0 40.6 0.0 0.1 64.7 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 7.1 0.2 26.2 0.1 0.9 2.5 0.0 0.1 0.3 0.4 0.9 353.6 0.0 0.2 0.0 2.5 3.7 1.9 5.2 7.9 2.2 1.3 2.8 5.6 4.8 0.2 6.7 3.7 0.2 0.0 0.0 4.2 0.1 3.8 16.6 19.6 1.8 1.4 16.6 8.4 0.4 1.5 22.5 3.7 0.0 0.0 3.6 0.1 0.0 1.3 0.0 0.5 0.2 0.8 0.0 0.0 28.5 46.0 0.0 0.7 37.2 1.2 0.0 4.3 0.0 0.0 0.2 0.0 14.2 2.5 6.1 0.0 0.8 0.0 0.0 0.4 46.2 1.0 0.1 0.6 7.2 5.0 1.5 27.6 0.0 0.0 0.4 74.6 0.0 0.0 4.1 1.4 0.0 0.1 2.2 0.0 0.0 6.8 36.4 0.1 3.2 0.0 0.0 65.6 SREK1 "DKFZp564B176, SFRS12, SRrp508, SRrp86" ENSG00000153914 "Splicing regulatory glutamic acid and lysine rich protein 1" Q8WXA9 5 66139971-66183615 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037673, HPA037674, HPA059332" Enhanced Enhanced "Nucleoplasm,Nuclear speckles" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nuclear speckles" "HPA037673: AB_2675598, HPA037674: AB_10671376, HPA059332: AB_2683983" "unprognostic (1.38e-1)" "unprognostic (2.51e-1)" "unprognostic (6.16e-2)" "unprognostic (1.52e-1)" "unprognostic (9.40e-2)" "prognostic favorable (2.54e-4)" "unprognostic (1.29e-2)" "unprognostic (7.67e-2)" "unprognostic (5.66e-3)" "unprognostic (2.19e-1)" "unprognostic (2.66e-2)" "unprognostic (5.48e-2)" "prognostic unfavorable (5.77e-4)" "unprognostic (1.63e-1)" "unprognostic (3.08e-1)" "unprognostic (6.76e-2)" "unprognostic (6.69e-2)" 5.6 6.5 6.7 4.4 6.8 20.2 5.9 8.0 8.4 7.4 9.9 6.7 4.5 8.0 5.2 5.4 7.0 4.2 4.9 6.3 7.2 4.8 6.1 6.2 5.9 6.1 6.4 6.4 8.5 6.6 8.1 5.2 6.1 5.4 4.3 9.5 7.0 3.8 4.7 9.0 7.4 3.2 6.0 7.4 6.5 4.8 7.0 5.8 8.0 3.3 4.1 5.5 5.7 7.4 5.5 6.7 8.5 5.5 3.9 7.5 9.5 6.1 3.3 3.1 3.4 9.5 6.3 8.3 7.4 4.5 4.1 7.4 4.3 5.7 5.3 6.0 10.3 7.9 18.0 7.2 3.4 7.0 8.9 4.5 5.6 3.7 4.2 6.4 5.2 4.6 7.4 5.5 3.4 5.6 7.2 16.2 4.8 2.1 3.3 10.2 4.1 6.3 5.6 9.2 10.3 7.3 5.8 2.7 5.1 6.1 7.2 8.7 5.9 5.2 3.3 7.3 6.4 6.0 4.5 8.9 5.1 11.2 5.5 4.9 2.7 2.8 2.4 2.1 2.6 3.2 2.2 2.8 2.3 3.8 2.6 2.6 2.1 3.8 1.9 3.1 2.4 1.5 6.7 6.8 8.0 8.4 6.3 7.2 6.1 6.4 6.1 6.0 7.0 7.4 72.6 93.0 143.5 70.2 67.6 66.0 84.8 69.3 58.6 64.3 64.1 51.4 80.8 60.1 98.8 46.0 116.7 84.6 72.1 59.5 37.2 59.3 46.5 91.2 124.1 83.3 77.8 65.6 71.4 55.4 86.7 80.1 72.4 107.5 97.0 80.5 55.0 68.3 50.2 67.3 73.3 64.2 79.3 54.4 50.2 62.3 83.6 55.4 42.7 40.3 62.3 63.4 53.5 98.0 85.2 54.7 41.8 76.8 70.7 83.7 49.8 32.8 112.2 89.8 46.0 92.3 87.2 78.9 62.0 49.1 69.3 120.7 63.7 85.2 62.5 91.2 SRRM1 "MGC39488, POP101, SRM160" ENSG00000133226 "Serine and arginine repetitive matrix 1" Q8IYB3 1 24631716-24673281 "Plasma proteins, Predicted intracellular proteins, Transporters" "mRNA processing, mRNA splicing" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049941, HPA058612" Supported Enhanced "Nuclear speckles" NA NA 20000 "Cluster 18: Basophils - Vesicular transport" "Cluster 51: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "HPA049941: AB_2680962, HPA058612: AB_2683778" "unprognostic (3.31e-2)" "unprognostic (3.81e-1)" "unprognostic (1.29e-1)" "unprognostic (3.78e-1)" "unprognostic (1.49e-1)" "unprognostic (7.71e-3)" "prognostic unfavorable (1.08e-4)" "unprognostic (3.83e-2)" "unprognostic (1.80e-3)" "unprognostic (2.38e-1)" "unprognostic (9.27e-2)" "unprognostic (5.08e-3)" "unprognostic (4.52e-2)" "unprognostic (4.50e-2)" "unprognostic (2.77e-2)" "unprognostic (1.88e-1)" "unprognostic (3.46e-1)" 43.2 32.8 28.5 30.7 32.9 68.9 45.3 37.2 35.8 62.6 33.8 48.8 27.7 50.7 83.8 37.5 58.4 22.9 40.5 28.3 29.4 31.2 32.1 40.2 40.3 32.6 31.1 79.2 35.7 26.2 37.6 33.3 33.7 53.5 26.9 52.4 40.6 31.9 52.0 54.8 43.2 30.6 27.4 45.7 36.8 39.3 30.7 31.4 39.8 21.5 37.0 41.6 50.3 46.0 52.4 40.4 79.2 74.2 44.4 46.0 78.0 57.7 40.5 59.1 67.4 45.2 88.1 115.0 36.6 50.4 39.2 66.0 82.1 58.2 78.4 39.2 54.3 89.9 83.3 53.0 30.7 101.3 58.5 30.6 34.9 48.4 68.1 66.4 53.7 55.2 92.8 65.5 61.5 44.1 96.3 69.6 139.4 42.9 29.0 89.4 63.3 58.0 52.4 51.6 49.3 43.0 63.5 54.5 45.5 59.8 49.3 50.7 56.7 54.2 53.2 71.4 62.5 54.7 46.0 138.3 58.4 122.4 61.0 32.3 18.1 20.9 21.6 23.3 26.7 19.9 20.4 21.3 20.7 20.0 18.6 21.6 23.2 29.7 27.5 16.8 16.5 16.9 28.5 32.9 37.2 35.8 28.3 29.4 32.6 31.1 33.7 27.4 30.7 46.0 231.5 157.0 165.3 67.9 266.8 302.3 280.8 194.6 271.5 178.4 164.6 188.0 154.8 128.7 172.7 121.4 118.9 152.1 315.1 146.5 199.6 174.1 330.2 211.3 247.6 170.7 118.4 230.1 53.6 147.2 170.0 177.2 142.2 260.0 241.0 148.6 140.7 225.6 149.5 124.5 56.7 174.4 120.1 178.7 311.3 134.1 167.7 205.3 154.7 45.9 286.6 187.1 256.4 58.8 173.2 147.5 149.1 150.8 236.8 329.8 141.8 198.4 145.5 186.9 138.1 252.3 220.3 219.4 223.3 282.5 295.4 241.2 288.6 135.9 194.3 308.9 SRRM2 "Cwc21, KIAA0324, SRL300, SRm300" ENSG00000167978 "Serine/arginine repetitive matrix 2" Q9UQ35 16 2752626-2772538 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 150.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041411, HPA066181" Supported Enhanced "Nuclear speckles" NA NA 17000 "Cluster 11: Basophils - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "HPA041411: AB_10796671, HPA066181: AB_2685630" "unprognostic (8.48e-2)" "unprognostic (1.80e-1)" "unprognostic (2.44e-1)" "unprognostic (1.81e-1)" "unprognostic (4.23e-2)" "prognostic favorable (6.77e-4)" "prognostic unfavorable (5.08e-4)" "unprognostic (7.39e-2)" "unprognostic (1.64e-1)" "unprognostic (4.74e-2)" "unprognostic (2.72e-1)" "unprognostic (3.50e-3)" "prognostic unfavorable (4.82e-4)" "unprognostic (1.05e-1)" "unprognostic (5.35e-2)" "unprognostic (1.26e-2)" "unprognostic (7.84e-2)" 195.2 215.4 203.8 115.7 211.0 270.4 193.4 229.1 374.7 255.3 232.5 239.3 127.0 219.7 69.9 222.8 253.9 94.3 246.5 205.6 201.2 212.5 252.5 198.6 125.4 222.7 197.7 265.5 315.1 115.9 171.0 89.2 208.7 217.8 102.8 134.1 243.0 86.9 306.6 224.6 261.5 100.3 180.2 250.7 269.6 146.9 227.5 108.4 231.4 96.9 95.2 211.5 211.7 234.5 108.1 134.7 212.9 147.1 147.1 141.9 125.1 119.8 68.1 105.5 93.5 111.5 123.1 192.2 87.3 134.6 88.2 151.6 170.2 153.6 110.9 139.3 177.5 164.8 284.5 192.9 65.6 171.9 229.6 146.3 145.6 155.0 182.8 210.4 110.5 136.5 187.5 184.1 98.7 186.5 162.6 270.9 196.9 76.4 75.1 286.2 84.0 150.4 136.4 109.7 138.1 120.8 158.1 162.0 98.7 141.7 147.2 137.4 157.1 148.8 150.3 97.9 149.8 161.2 131.6 402.9 51.7 124.0 102.2 150.8 24.0 13.3 8.2 10.6 7.9 15.9 10.4 8.1 5.8 22.9 9.1 12.0 48.2 60.5 10.5 31.9 5.9 3.0 203.8 211.0 229.1 374.7 205.6 201.2 222.7 197.7 208.7 180.2 227.5 234.5 286.4 141.1 232.4 134.8 221.3 310.5 430.1 204.0 178.2 416.5 271.8 283.3 139.0 147.3 180.5 167.3 291.9 179.3 289.0 244.4 66.5 156.3 83.1 285.4 457.7 230.3 189.6 191.6 71.1 179.5 204.8 235.0 296.2 379.3 134.8 273.1 158.8 183.8 157.2 439.1 76.7 245.2 162.8 124.5 238.7 77.2 251.6 208.1 120.9 116.2 160.9 239.8 195.7 94.0 109.6 159.9 188.4 192.2 262.3 352.3 192.5 99.3 146.6 358.1 197.2 366.8 391.0 231.8 253.7 219.2 365.1 276.2 237.5 339.5 236.5 377.8 SRSF11 "NET2, p54, SFRS11" ENSG00000116754 "Serine and arginine rich splicing factor 11" Q05519 1 70205682-70253052 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008762 Supported Supported "Nuclear speckles" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 50: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "HPA008762: AB_1856782" "unprognostic (7.82e-3)" "unprognostic (1.69e-1)" "unprognostic (2.28e-2)" "unprognostic (2.85e-1)" "unprognostic (5.32e-3)" "unprognostic (1.30e-3)" "prognostic unfavorable (3.91e-4)" "unprognostic (2.23e-3)" "unprognostic (5.65e-3)" "unprognostic (3.18e-2)" "unprognostic (1.22e-1)" "unprognostic (6.25e-3)" "prognostic unfavorable (6.53e-6)" "unprognostic (7.79e-2)" "unprognostic (1.63e-1)" "unprognostic (1.90e-1)" "unprognostic (1.43e-2)" 76.4 67.0 39.4 51.4 42.6 136.8 76.9 48.1 64.6 86.6 40.0 73.7 44.7 75.9 70.0 62.1 83.7 45.1 51.9 39.4 46.5 68.8 94.1 70.1 75.8 42.0 40.7 96.3 85.7 43.0 79.8 56.1 43.7 73.7 45.0 57.7 69.5 40.8 66.3 75.9 84.9 39.3 39.7 89.8 72.9 58.4 41.4 75.4 86.2 32.9 64.7 68.5 75.0 47.9 92.8 46.2 118.4 76.2 59.5 79.7 162.4 111.6 57.5 89.0 80.3 81.6 68.0 156.6 74.7 56.5 58.4 77.4 151.5 61.4 120.7 105.9 118.1 159.0 112.4 98.5 71.1 221.0 63.3 64.2 76.0 82.5 83.5 111.3 80.4 79.0 159.1 96.1 88.7 36.4 133.3 163.1 190.9 72.3 76.9 156.1 130.9 99.9 104.3 65.7 99.3 82.1 94.5 101.1 139.8 109.1 80.9 98.1 96.0 97.8 70.4 71.3 102.3 110.4 94.5 169.9 70.2 161.3 87.7 111.7 63.5 103.6 65.7 51.6 74.9 76.3 67.0 65.2 66.1 70.7 72.2 67.8 31.7 85.8 64.6 91.7 80.4 52.7 39.4 42.6 48.1 64.6 39.4 46.5 42.0 40.7 43.7 39.7 41.4 47.9 198.6 211.5 224.9 90.4 208.6 354.0 295.5 229.6 222.5 164.8 166.9 171.7 119.6 115.8 184.5 195.0 118.9 242.0 243.4 123.8 115.4 151.0 64.4 160.0 267.9 186.8 173.8 218.5 219.0 135.3 253.1 228.9 165.6 231.0 194.1 218.1 146.3 152.6 150.4 159.9 183.0 158.3 150.5 124.9 244.4 56.9 255.7 155.4 168.9 126.5 183.1 115.5 145.2 168.9 219.8 144.9 104.7 264.4 234.9 317.8 122.1 101.4 157.8 158.1 170.9 199.1 218.3 270.0 138.0 181.4 353.6 303.7 226.2 195.5 172.9 315.0 SRSF4 "SFRS4, SRP75" ENSG00000116350 "Serine and arginine rich splicing factor 4" Q08170 1 29147743-29181900 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050975 Supported Supported "Nuclear speckles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 36: HEL - Hemostasis" "Cluster 22: Epithelial cell types - Mixed function" "Nuclear speckles" "HPA050975: AB_2681296" "unprognostic (3.26e-3)" "unprognostic (8.08e-2)" "unprognostic (1.29e-2)" "unprognostic (1.57e-3)" "unprognostic (1.37e-1)" "unprognostic (5.89e-2)" "unprognostic (1.89e-3)" "unprognostic (1.63e-1)" "prognostic unfavorable (3.27e-4)" "unprognostic (2.36e-1)" "unprognostic (1.75e-1)" "prognostic unfavorable (4.26e-4)" "prognostic unfavorable (4.30e-4)" "unprognostic (6.25e-3)" "unprognostic (2.80e-1)" "unprognostic (7.75e-3)" "unprognostic (1.60e-2)" 84.7 61.1 43.4 46.8 45.4 77.5 78.2 47.6 46.6 82.3 44.1 86.7 49.6 79.7 38.6 73.5 71.7 36.4 61.9 43.0 46.9 62.9 95.8 83.5 57.4 44.8 43.7 88.2 61.6 38.7 56.0 57.6 45.6 72.0 35.6 51.8 62.5 39.6 94.1 76.2 73.1 40.6 43.0 81.9 66.7 44.5 45.0 63.2 73.7 51.7 43.4 77.7 76.6 46.1 108.2 63.5 117.0 42.8 83.9 63.0 72.5 87.6 65.5 103.3 88.0 58.6 64.9 122.2 79.9 74.5 66.9 99.0 99.7 81.4 104.5 148.6 118.9 185.7 95.6 92.9 87.2 127.8 114.0 51.1 101.1 87.7 111.8 83.9 86.6 70.2 154.8 95.7 71.1 54.1 162.2 110.4 125.2 64.4 60.0 150.6 126.9 83.3 71.1 110.0 71.3 81.4 107.4 61.5 105.8 103.4 41.0 76.3 84.2 82.9 66.1 91.0 146.4 88.0 70.6 134.5 79.4 161.0 91.9 72.7 45.7 102.2 64.6 55.1 63.3 49.0 59.7 70.5 55.8 53.1 51.0 55.0 89.6 48.4 62.3 43.2 78.9 51.1 43.4 45.4 47.6 46.6 43.0 46.9 44.8 43.7 45.6 43.0 45.0 46.1 142.3 80.1 129.8 23.8 94.2 99.8 179.6 65.0 91.0 70.2 50.2 42.9 51.1 45.8 92.8 51.5 85.5 132.7 100.0 68.4 54.8 64.9 8.2 85.4 98.4 131.0 39.0 114.3 20.1 47.2 124.6 87.8 76.5 99.4 91.7 76.2 101.0 75.9 68.8 57.2 21.1 72.7 59.0 69.8 79.0 11.6 85.7 83.4 55.2 14.0 88.6 74.8 92.7 19.6 19.6 56.3 78.8 89.1 121.4 172.3 83.1 58.3 91.7 108.3 72.3 99.5 97.4 64.7 51.9 95.9 103.3 142.8 105.1 75.9 78.7 210.4 SRSF6 "B52, SFRS6, SRP55" ENSG00000124193 "Serine and arginine rich splicing factor 6" Q13247 20 43457893-43466046 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029005, CAB034889" Supported Supported "Nuclear speckles" NA NA 50000 "Cluster 39: Non-specific - mRNA processing" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nuclear speckles" "CAB034889: AB_785899, HPA029005: AB_10610424" "unprognostic (1.51e-1)" "unprognostic (1.26e-1)" "unprognostic (1.98e-1)" "unprognostic (3.25e-2)" "unprognostic (6.41e-2)" "unprognostic (3.91e-2)" "prognostic unfavorable (3.86e-4)" "unprognostic (3.99e-3)" "unprognostic (4.39e-2)" "unprognostic (2.07e-1)" "unprognostic (1.27e-3)" "unprognostic (6.03e-3)" "prognostic unfavorable (2.82e-4)" "unprognostic (1.73e-1)" "unprognostic (2.70e-1)" "unprognostic (4.31e-1)" "unprognostic (1.18e-2)" 43.3 53.7 34.0 34.5 37.5 115.9 56.2 41.4 43.8 44.2 52.7 37.8 36.3 52.7 59.7 32.8 47.4 31.4 31.4 33.3 39.6 47.4 50.3 40.3 48.4 34.5 34.7 58.5 66.3 41.8 48.0 39.3 35.6 48.7 43.4 38.7 45.3 30.0 30.5 48.7 45.4 39.7 35.6 55.9 47.4 30.3 35.7 53.7 50.8 18.1 40.8 29.7 30.4 47.3 52.7 79.1 88.7 57.3 50.7 67.7 86.3 79.6 38.3 55.4 47.1 112.9 55.9 95.9 73.9 73.3 45.1 77.6 91.7 116.9 71.7 40.2 85.7 74.6 83.3 94.1 62.3 94.9 78.9 115.7 61.9 51.0 46.2 85.1 52.7 83.8 63.3 54.5 52.6 112.3 144.5 107.6 57.8 87.4 107.4 100.2 54.4 76.9 63.1 93.7 69.0 90.9 89.5 108.7 105.0 61.7 70.4 103.3 54.9 57.9 61.6 49.9 67.3 98.2 67.3 131.4 69.9 67.2 42.8 26.0 19.9 9.7 19.7 33.4 22.4 16.0 20.8 19.1 24.5 15.9 27.3 25.7 10.8 21.2 29.6 20.4 18.7 22.9 34.0 37.5 41.4 43.8 33.3 39.6 34.5 34.7 35.6 35.6 35.7 47.3 78.9 64.1 80.0 49.6 75.8 94.4 61.0 58.5 50.7 48.9 110.7 78.7 28.7 75.8 61.3 46.0 39.6 97.8 103.3 67.8 88.0 60.2 12.3 60.1 87.7 62.3 101.4 71.1 32.1 43.7 108.2 80.0 70.8 79.1 97.0 103.2 60.7 94.7 56.5 32.0 37.2 97.2 46.8 73.2 93.7 14.7 55.0 77.3 101.4 26.2 61.2 45.0 37.0 89.0 79.6 46.2 74.3 44.8 49.3 68.9 66.7 67.7 47.6 46.4 59.2 166.1 99.8 53.8 61.0 51.5 98.3 139.1 76.4 90.7 105.5 55.3 SSH3 "FLJ10928, FLJ20515" ENSG00000172830 "Slingshot protein phosphatase 3" Q8TE77 11 67303478-67312607 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 11.6;eosinophil: 11.1" "Lineage enriched" "Detected in many" 5 "granulocytes: 11.6" "Cell line enhanced" "Detected in many" "HaCaT: 64.9;MCF7: 64.1;RT4: 111.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019949, HPA019957" Approved Approved "Nuclear speckles,Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "Nuclear speckles, Cytosol" "Plasma membrane, Actin filaments" "HPA019949: AB_1857498, HPA019957: AB_1857499" "unprognostic (4.38e-2)" "unprognostic (1.37e-1)" "unprognostic (3.50e-3)" "unprognostic (3.73e-2)" "unprognostic (2.61e-3)" "unprognostic (9.30e-2)" "unprognostic (2.99e-1)" "unprognostic (1.84e-1)" "unprognostic (1.63e-1)" "unprognostic (2.45e-2)" "prognostic unfavorable (2.89e-4)" "unprognostic (1.50e-1)" "unprognostic (2.06e-2)" "unprognostic (1.47e-1)" "unprognostic (3.20e-1)" "unprognostic (4.94e-3)" "unprognostic (6.78e-3)" 14.4 7.8 8.9 4.0 12.0 9.3 16.2 14.1 11.6 25.9 9.5 19.3 13.3 16.0 7.5 41.9 18.3 11.5 12.5 9.1 10.1 13.1 10.9 12.7 3.1 14.6 10.8 23.5 15.3 9.8 9.7 6.5 13.2 29.9 9.3 1.2 26.2 28.8 6.8 25.2 15.0 6.1 12.3 9.4 20.1 2.3 11.5 1.9 16.3 3.8 4.8 37.4 32.5 14.9 17.3 18.7 0.4 0.6 11.4 11.8 18.8 10.3 13.7 5.6 5.1 21.2 46.8 1.0 32.5 10.5 11.9 64.9 6.0 46.4 2.8 3.6 6.3 4.3 32.2 9.9 8.2 0.9 16.0 12.2 40.5 8.3 8.3 12.9 6.3 0.4 0.1 1.5 6.2 64.1 0.8 7.3 4.2 48.9 13.8 20.6 0.6 3.1 18.2 111.2 3.7 5.8 24.8 41.0 12.8 6.3 57.1 15.3 10.4 4.5 9.8 12.7 2.7 1.5 0.9 0.5 12.7 6.9 4.9 11.6 1.5 11.1 2.0 2.3 1.7 0.2 1.9 1.7 1.7 0.1 0.8 0.8 4.4 1.5 1.1 1.1 1.8 1.1 8.9 12.0 14.1 11.6 9.1 10.1 14.6 10.8 13.2 12.3 11.5 14.9 7.6 3.2 8.7 8.5 0.9 7.0 20.8 25.2 11.4 0.8 21.3 17.3 3.8 20.0 23.4 16.5 0.0 15.1 3.3 28.3 3.9 19.4 0.1 8.3 5.6 4.7 3.6 5.2 4.2 21.6 24.9 8.0 20.9 17.8 3.8 8.1 3.9 5.0 7.7 1.7 5.3 14.4 24.4 6.2 3.1 0.6 13.1 4.8 8.8 2.8 9.2 4.8 7.2 0.0 15.9 20.0 21.0 12.0 0.7 15.4 20.2 7.4 11.6 0.5 0.0 4.9 9.2 0.5 0.4 27.0 10.4 15.7 4.4 5.3 21.4 26.8 STK17A DRAK1 ENSG00000164543 "Serine/threonine kinase 17a" Q9UEE5 7 43582758-43650713 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 644.6;T-cells: 273.7;Urothelial cells: 326.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018138, HPA037979" Uncertain Supported "Nuclear speckles,Plasma membrane" Yes No "Cluster 48: NK-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 22: Epithelial cell types - Mixed function" "Nuclear speckles" "Plasma membrane" "HPA018138: AB_2669784, HPA037979: AB_10795247" "unprognostic (1.81e-3)" "unprognostic (1.08e-2)" "unprognostic (2.67e-1)" "unprognostic (5.41e-2)" "unprognostic (5.11e-2)" "unprognostic (3.35e-2)" "unprognostic (1.03e-2)" "unprognostic (9.15e-3)" "unprognostic (2.07e-1)" "unprognostic (6.34e-2)" "unprognostic (1.36e-2)" "unprognostic (6.61e-2)" "unprognostic (2.99e-3)" "unprognostic (3.76e-2)" "unprognostic (3.08e-1)" "unprognostic (1.97e-3)" "unprognostic (3.66e-1)" 6.7 8.1 3.9 7.9 4.2 4.8 5.2 6.9 4.9 4.0 4.0 6.4 3.2 3.5 1.2 7.2 3.9 5.3 10.8 4.0 4.1 6.3 4.6 9.4 14.4 3.4 4.4 6.2 9.1 0.8 4.2 3.2 3.6 4.3 2.4 5.5 5.8 2.1 9.9 4.6 11.5 3.3 3.6 12.6 9.5 9.0 4.3 9.0 3.8 2.5 13.5 5.6 5.0 3.1 5.8 8.2 9.0 5.3 7.8 8.3 1.9 12.3 15.1 6.6 5.9 7.5 3.1 7.9 20.2 15.3 17.8 8.5 3.6 17.4 10.4 16.9 7.0 9.3 8.2 8.4 4.9 21.1 5.6 6.4 26.4 8.2 8.6 36.4 12.6 11.0 16.7 15.1 9.6 3.6 18.2 8.0 17.3 4.1 18.3 8.4 6.9 14.2 15.6 6.7 6.9 11.2 8.1 8.5 6.1 13.6 6.5 10.8 16.9 20.7 8.3 14.3 17.2 13.3 11.2 13.5 18.4 14.0 31.7 0.5 0.0 2.7 2.0 0.0 1.5 2.4 2.0 3.2 0.1 2.2 3.0 3.0 1.6 4.9 0.1 0.4 1.3 0.9 3.9 4.2 6.9 4.9 4.0 4.1 3.4 4.4 3.6 3.6 4.3 3.1 44.2 121.8 33.1 29.0 237.8 181.9 644.6 64.5 99.6 2.9 17.7 37.8 28.7 7.2 69.8 20.2 10.4 54.8 222.3 54.4 33.2 153.0 47.0 129.1 17.4 35.2 7.2 54.1 9.5 95.4 23.3 39.1 78.0 88.3 38.8 17.7 17.9 9.6 16.9 0.0 5.6 34.3 38.7 20.3 65.9 14.7 5.9 60.9 35.6 34.7 42.1 7.9 221.4 39.2 3.7 89.4 73.0 2.6 81.2 192.6 23.8 13.2 42.4 26.3 6.6 39.4 51.3 75.8 36.1 42.3 136.1 66.8 273.7 27.0 18.0 326.1 STK19 "D6S60, G11, RP1" ENSG00000204344 "Serine/threonine kinase 19" P49842 6 31971091-31982821 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in all" 4 "Proximal tubular cells: 348.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HDLM-2: 1.4;HEL: 1.5;HL-60: 1.6;REH: 1.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031511, HPA068559" Uncertain Supported "Nuclear speckles" NA NA "Cluster 30: Non-specific - Translation" "Cluster 72: Non-specific - Transcription" "Cluster 36: HEL - Hemostasis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles" "HPA031511: AB_2673915, HPA068559: AB_2686004" "unprognostic (1.65e-1)" "unprognostic (2.30e-1)" "unprognostic (3.31e-1)" "unprognostic (1.86e-1)" "unprognostic (2.63e-1)" "unprognostic (1.67e-1)" "unprognostic (1.15e-2)" "unprognostic (4.26e-2)" "prognostic unfavorable (1.18e-4)" "unprognostic (3.95e-2)" "unprognostic (2.76e-3)" "unprognostic (2.25e-2)" "unprognostic (1.08e-2)" "unprognostic (1.02e-1)" "unprognostic (1.60e-1)" "unprognostic (2.40e-1)" "unprognostic (4.10e-1)" 1.5 3.6 0.1 0.2 0.1 0.0 1.3 0.4 0.9 2.1 0.0 2.5 0.0 1.4 0.3 1.9 1.0 0.1 1.2 0.0 0.0 1.5 2.2 1.3 0.0 0.0 0.0 1.1 1.1 0.2 1.4 0.4 0.1 2.1 0.0 0.2 0.9 0.1 1.3 2.5 0.7 0.0 0.0 1.2 1.3 1.5 0.1 0.1 1.2 0.0 0.1 2.0 1.5 0.4 0.0 0.1 0.0 0.4 1.1 0.7 0.0 0.3 0.1 0.2 0.4 0.0 0.7 0.6 0.3 0.5 0.0 0.6 0.0 0.2 0.3 1.4 0.4 1.5 0.3 0.0 0.5 1.6 0.0 0.6 0.0 0.3 0.1 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 1.1 0.4 0.0 0.0 0.1 0.3 0.1 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.9 0.0 0.7 0.2 0.0 0.0 1.1 0.0 0.1 0.3 0.2 0.6 0.2 0.0 0.8 0.2 0.3 0.1 0.1 0.3 0.4 0.4 0.0 0.1 0.1 0.1 0.4 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 21.2 9.6 21.5 13.7 16.4 13.0 14.0 23.0 13.6 11.8 26.6 27.6 8.1 18.6 24.6 22.0 20.9 37.2 22.4 13.8 39.2 26.3 85.8 27.8 31.8 20.6 19.3 4.6 8.7 28.3 20.0 23.3 19.4 20.7 9.5 20.1 14.3 21.1 19.3 10.1 8.0 17.3 18.3 8.8 10.0 76.0 20.2 18.3 17.8 11.2 12.5 30.2 13.4 4.5 6.5 23.6 16.4 18.4 11.9 13.2 15.0 348.9 41.8 21.9 32.9 19.6 21.1 39.5 21.0 17.9 18.2 49.7 19.8 45.1 13.1 11.8 SYF2 "CBPIN, DKFZp564O2082, fSAP29, NTC31, p29" ENSG00000117614 "SYF2 pre-mRNA splicing factor" O95926 1 25222276-25232502 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018265, HPA070710" Approved Supported "Nuclear speckles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear speckles" "HPA018265: AB_10962002, HPA070710: AB_2686301" "unprognostic (4.19e-3)" "unprognostic (1.58e-2)" "unprognostic (9.98e-2)" "unprognostic (9.29e-2)" "unprognostic (1.21e-1)" "unprognostic (6.76e-2)" "unprognostic (6.76e-3)" "unprognostic (7.40e-3)" "unprognostic (2.36e-2)" "unprognostic (3.26e-1)" "unprognostic (1.33e-2)" "unprognostic (7.58e-2)" "unprognostic (4.89e-2)" "unprognostic (2.27e-2)" "unprognostic (4.80e-2)" "unprognostic (1.45e-3)" "prognostic favorable (5.72e-4)" 75.3 56.5 37.8 42.6 38.4 147.6 66.9 39.9 48.4 70.1 39.0 71.6 55.4 59.9 72.2 49.3 63.7 40.7 50.0 36.9 41.6 64.0 48.3 46.4 63.8 39.3 38.4 104.5 59.1 67.8 35.3 57.1 40.3 50.3 59.4 29.5 52.0 51.3 89.1 58.5 57.7 47.0 39.2 55.9 61.9 26.9 38.4 77.6 59.0 57.8 76.8 63.2 60.1 41.4 54.0 22.0 54.9 45.4 85.2 109.0 42.4 56.1 91.0 52.7 47.8 13.7 73.0 46.2 75.6 68.1 39.8 47.3 47.6 43.2 76.4 76.2 39.4 52.8 56.1 41.8 86.6 75.9 54.3 79.4 118.2 54.3 75.2 100.4 76.0 61.8 42.0 74.4 75.2 19.8 77.6 104.0 71.7 78.9 32.4 51.3 46.3 78.9 86.9 28.6 47.8 69.5 49.1 44.5 160.5 47.7 38.3 91.5 61.8 45.9 40.6 87.0 46.8 86.7 83.4 48.6 67.6 77.7 45.2 185.5 82.1 222.9 79.1 98.4 95.7 140.0 102.4 99.9 70.0 125.5 108.4 102.0 337.6 111.3 121.6 67.3 129.2 92.7 37.8 38.4 39.9 48.4 36.9 41.6 39.3 38.4 40.3 39.2 38.4 41.4 160.7 128.2 112.8 6.8 176.0 159.3 123.0 238.5 111.5 74.3 134.9 174.1 108.1 147.3 151.3 189.4 83.4 195.7 203.9 211.7 246.5 158.6 78.7 153.2 125.9 137.4 111.4 117.6 10.6 174.2 130.1 121.1 59.1 166.8 232.4 120.9 154.9 131.3 126.4 58.9 10.2 166.0 181.0 231.5 155.4 32.1 214.6 155.4 108.5 3.7 251.8 95.0 217.3 6.0 12.5 154.5 221.1 164.7 83.0 109.5 322.0 273.4 151.0 90.5 164.3 139.5 142.5 98.2 108.8 88.1 171.3 280.6 176.8 95.9 171.8 147.2 SYNPO2L FLJ12921 ENSG00000166317 "Synaptopodin 2 like" Q9H987 10 73644881-73663803 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 18 "heart muscle: 262.3;skeletal muscle: 279.2;tongue: 87.2" "Cell type enriched" "Detected in some" 52 "Cardiomyocytes: 665.1" "Group enriched" "Detected in some" 6 "breast cancer: 1.5;head and neck cancer: 1.4;prostate cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "CACO-2: 4.1;HSkMC: 3.2;RH-30: 3.0;SK-BR-3: 3.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA055192, HPA057142" Enhanced Supported "Nuclear speckles,Cell Junctions,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nuclear speckles" "Cell Junctions, Cytosol" "HPA055192: AB_2682732, HPA057142: AB_2683348" "unprognostic (2.75e-1)" "unprognostic (1.58e-1)" "unprognostic (1.20e-3)" "unprognostic (3.65e-3)" "unprognostic (1.27e-1)" "unprognostic (1.05e-1)" "unprognostic (1.33e-1)" "unprognostic (4.54e-2)" "unprognostic (3.30e-1)" "unprognostic (2.49e-2)" "unprognostic (4.50e-2)" "unprognostic (2.32e-1)" "unprognostic (7.44e-4)" "unprognostic (1.09e-1)" "unprognostic (1.01e-1)" "unprognostic (1.72e-2)" "unprognostic (1.34e-1)" 0.1 0.5 0.7 0.1 0.7 0.3 3.6 0.8 0.9 0.4 0.1 0.0 0.1 0.1 0.1 11.8 0.1 0.1 262.3 0.7 0.5 0.1 0.1 1.2 0.2 0.7 0.6 0.2 0.4 0.0 0.1 0.6 0.5 3.1 0.0 0.4 4.8 0.0 279.2 0.3 0.0 0.0 0.5 0.2 0.1 0.3 0.6 0.1 0.2 87.2 0.2 0.0 1.1 0.7 0.0 0.0 0.4 0.1 0.0 0.0 0.3 0.5 0.6 0.1 0.0 4.1 0.2 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.2 0.0 0.3 0.1 0.0 3.2 0.0 0.6 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 3.0 0.1 0.0 0.1 0.1 0.1 0.0 3.2 0.0 0.1 0.1 0.1 0.0 0.2 0.4 0.0 0.1 0.5 0.0 0.0 0.0 0.2 0.0 0.6 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.2 0.0 0.0 0.7 0.7 0.8 0.9 0.7 0.5 0.7 0.6 0.5 0.5 0.6 0.7 0.5 3.2 0.0 0.3 0.9 1.5 1.4 0.0 2.2 1.9 1.0 0.8 665.1 0.0 0.7 0.0 2.1 0.2 0.5 0.0 0.0 0.0 2.6 0.1 0.4 5.0 0.0 0.0 0.3 0.0 0.2 12.6 0.0 0.3 1.3 0.3 0.0 0.4 0.2 0.0 0.9 0.0 0.0 0.6 2.1 1.1 0.9 0.8 1.8 1.0 0.3 0.4 0.0 1.5 1.1 0.0 0.0 0.4 0.3 0.9 0.0 0.2 0.7 1.2 0.0 12.0 5.2 0.8 1.3 0.4 0.4 0.0 0.7 0.2 0.0 1.0 TAB1 MAP3K7IP1 ENSG00000100324 "TGF-beta activated kinase 1 (MAP3K7) binding protein 1" Q15750 22 39399778-39437060 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 55.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032328, HPA039988, HPA057104" Approved Approved "Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 35: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 56: Bipolar cells - Visual perception" "Nuclear speckles" "CAB032328: AB_2281637, HPA039988: AB_2676787, HPA057104: AB_2683338" "unprognostic (1.76e-1)" "unprognostic (1.79e-2)" "unprognostic (7.88e-2)" "unprognostic (6.73e-3)" "unprognostic (9.23e-3)" "unprognostic (4.30e-2)" "unprognostic (6.44e-2)" "unprognostic (1.79e-2)" "unprognostic (4.93e-2)" "unprognostic (7.05e-2)" "unprognostic (1.63e-1)" "unprognostic (7.35e-2)" "unprognostic (7.80e-3)" "unprognostic (1.86e-1)" "unprognostic (1.25e-1)" "unprognostic (1.33e-1)" "unprognostic (1.18e-1)" 13.1 14.8 18.2 9.0 20.6 9.7 12.9 17.0 19.8 18.2 10.6 18.9 10.7 16.5 6.2 13.8 15.9 7.4 17.0 17.3 16.1 12.4 16.6 11.0 11.1 18.7 19.3 20.5 15.6 10.0 10.5 8.6 17.7 16.7 5.4 12.2 13.7 10.9 19.9 17.4 13.5 8.7 15.8 15.9 14.7 10.2 18.5 11.9 13.3 10.7 7.8 17.9 14.9 20.6 15.0 15.3 15.2 17.5 15.8 13.2 13.5 12.3 15.1 18.4 17.3 14.2 10.6 22.5 9.4 12.0 10.3 18.0 15.5 18.0 7.2 17.6 24.8 9.9 19.0 14.2 13.7 18.8 18.3 13.5 15.7 13.9 15.1 14.0 13.6 13.5 18.4 15.0 9.3 9.7 14.6 15.6 10.6 23.6 15.4 26.0 21.6 22.6 14.4 15.7 13.5 9.9 17.4 21.5 15.4 9.4 17.6 20.4 11.8 12.8 20.2 9.9 10.1 23.6 16.2 16.4 15.1 13.1 12.8 0.8 5.6 4.1 4.3 4.3 3.4 3.3 2.6 3.5 5.0 3.2 4.1 3.9 0.7 3.3 4.5 2.3 2.8 4.3 18.2 20.6 17.0 19.8 17.3 16.1 18.7 19.3 17.7 15.8 18.5 20.6 6.0 3.2 6.7 17.9 7.0 2.0 2.8 4.0 6.8 55.2 5.9 6.9 7.4 8.6 4.1 3.7 18.8 12.4 4.7 4.9 0.0 6.2 1.6 4.5 7.0 5.4 11.4 6.9 9.1 3.8 7.9 6.2 7.1 4.4 5.1 12.5 2.2 4.7 7.1 28.6 12.6 4.8 0.0 6.0 1.0 3.2 7.8 6.4 5.4 9.4 8.6 12.1 8.2 7.5 18.6 5.4 4.1 9.1 8.4 2.8 7.6 5.4 4.7 18.8 6.6 6.4 7.4 8.2 9.1 5.5 3.3 5.6 8.1 10.3 4.9 1.8 TAB3 MAP3K7IP3 ENSG00000157625 "TGF-beta activated kinase 1 (MAP3K7) binding protein 3" Q8N5C8 X 30827442-30975084 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034980, HPA034981" Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Nuclear speckles, Cytosol" "HPA034980: AB_10602708, HPA034981: AB_2674394" "unprognostic (4.39e-1)" "unprognostic (2.22e-1)" "unprognostic (3.04e-2)" "unprognostic (1.73e-1)" "unprognostic (6.35e-2)" "unprognostic (2.95e-3)" "unprognostic (1.49e-2)" "unprognostic (1.73e-2)" "unprognostic (3.10e-1)" "unprognostic (2.14e-1)" "unprognostic (1.65e-1)" "unprognostic (3.51e-1)" "prognostic favorable (8.45e-4)" "unprognostic (5.91e-2)" "unprognostic (1.25e-1)" "unprognostic (9.12e-2)" "unprognostic (2.75e-1)" 8.1 7.6 3.6 8.0 4.5 16.8 8.9 3.9 6.7 8.5 20.6 9.6 7.7 18.0 8.9 16.6 9.7 8.1 8.6 5.3 4.0 14.3 27.1 9.0 8.9 5.2 6.5 12.2 24.9 31.8 6.5 11.6 4.7 14.6 9.5 23.9 9.7 12.6 10.7 9.7 7.9 13.3 3.1 8.5 12.5 15.3 4.4 9.7 10.0 8.9 12.6 7.2 8.3 5.7 40.2 9.5 9.6 9.8 7.3 11.0 10.1 12.2 15.3 8.0 9.1 10.8 33.5 18.1 7.3 14.2 15.5 20.4 14.8 31.0 11.6 31.2 14.2 16.9 10.9 26.4 6.3 18.0 12.7 8.0 18.2 13.8 35.0 13.9 13.5 13.5 19.7 14.4 10.6 19.4 14.4 9.1 11.5 7.2 15.9 9.1 16.8 13.5 13.3 11.6 8.0 11.3 13.6 20.3 26.0 17.8 17.5 7.1 13.0 8.9 13.0 44.8 11.3 18.6 15.3 17.8 13.9 8.3 12.7 0.0 0.1 0.2 0.1 0.2 0.2 0.2 0.2 0.1 0.1 0.3 0.2 0.2 0.1 0.9 0.2 0.0 0.1 0.1 3.6 4.5 3.9 6.7 5.3 4.0 5.2 6.5 4.7 3.1 4.4 5.7 9.6 12.8 13.2 14.0 10.2 9.1 7.9 7.2 6.8 7.4 10.0 5.3 11.4 20.0 10.5 11.0 12.5 15.1 11.0 12.3 3.9 8.4 1.5 13.0 23.0 8.8 7.2 39.2 23.2 6.9 4.9 5.6 12.8 11.9 14.5 28.6 10.0 26.0 7.7 11.8 22.3 10.8 6.1 16.0 13.7 3.4 10.8 12.6 5.4 20.6 11.5 6.7 3.1 21.6 21.2 9.9 11.2 16.1 7.3 12.6 7.3 11.2 19.6 20.4 0.0 6.3 6.7 3.3 2.2 9.6 10.1 22.4 10.9 24.4 9.8 13.2 TADA2A "ADA2, ADA2A, hADA2, TADA2L" ENSG00000276234 "Transcriptional adaptor 2A" 17 37406886-37479725 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 125.0;Late spermatids: 87.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076497 Approved "Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 71: Testis - DNA repair" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Nuclear speckles" "HPA076497: AB_2686801" "unprognostic (3.49e-1)" "unprognostic (5.12e-2)" "unprognostic (7.32e-2)" "unprognostic (7.86e-2)" "unprognostic (4.80e-1)" "unprognostic (1.23e-3)" "unprognostic (3.58e-2)" "unprognostic (1.04e-1)" "unprognostic (6.13e-3)" "unprognostic (8.18e-2)" "unprognostic (1.10e-3)" "unprognostic (7.81e-2)" "prognostic unfavorable (2.25e-5)" "unprognostic (4.38e-2)" "unprognostic (1.06e-1)" "unprognostic (2.56e-2)" "unprognostic (4.41e-2)" 3.8 3.5 2.8 3.1 3.6 2.6 3.8 5.5 5.3 4.9 1.4 5.0 1.8 5.0 2.6 3.8 4.9 1.5 4.2 2.8 2.9 3.9 4.7 3.3 2.0 2.7 3.1 3.9 5.0 1.2 4.6 1.5 2.9 4.4 2.8 5.0 3.9 1.7 6.2 4.8 5.3 1.5 2.8 5.4 4.3 10.1 3.3 1.7 5.5 1.5 3.2 4.9 4.3 4.1 0.8 6.4 6.2 4.9 3.0 4.3 6.9 4.0 4.0 6.9 5.0 7.8 0.0 12.7 5.9 2.9 9.0 10.0 8.9 4.9 7.6 8.9 7.6 6.6 8.2 4.3 5.3 10.4 4.0 3.2 3.3 7.9 3.9 3.7 6.9 16.3 11.0 3.7 9.0 3.4 19.7 8.5 4.9 3.1 4.5 13.5 19.3 10.4 4.4 6.5 7.2 6.9 5.3 2.8 4.9 6.4 8.9 3.4 5.7 7.9 6.9 5.7 6.2 6.4 6.1 16.6 7.6 4.4 6.8 2.4 3.8 4.5 5.4 4.2 3.9 3.9 3.4 4.5 4.7 7.1 5.3 5.1 0.5 3.1 5.9 8.6 3.2 2.8 2.8 3.6 5.5 5.3 2.8 2.9 2.7 3.1 2.9 2.8 3.3 4.1 6.8 6.4 9.3 8.5 6.1 2.5 6.7 9.7 6.8 15.1 3.9 4.4 7.4 8.6 11.3 9.2 16.7 15.2 11.0 4.3 1.9 7.1 125.0 7.5 9.7 8.2 4.2 9.9 22.9 5.9 9.7 5.5 5.1 6.8 10.1 9.1 5.7 3.9 8.0 23.5 19.7 7.3 4.1 5.5 4.7 87.9 8.1 6.5 1.8 20.6 10.5 11.4 5.2 17.6 21.6 6.6 4.0 7.9 7.1 5.3 6.6 5.1 11.4 21.8 13.1 8.7 10.1 27.3 33.5 4.8 3.3 5.1 6.8 7.4 7.4 4.0 TADA2B MGC21874 ENSG00000173011 "Transcriptional adaptor 2B" Q86TJ2 4 7041899-7057952 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 40.4;Rod photoreceptor cells: 38.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035770 Approved Approved "Nuclear speckles" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 2: Karpas-707 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Nuclear speckles" "HPA035770: AB_10603993" "unprognostic (1.52e-1)" "unprognostic (1.50e-1)" "unprognostic (6.61e-2)" "unprognostic (2.77e-3)" "unprognostic (1.14e-2)" "unprognostic (1.70e-2)" "unprognostic (1.72e-1)" "unprognostic (1.98e-2)" "unprognostic (2.99e-1)" "unprognostic (6.03e-2)" "unprognostic (8.91e-3)" "unprognostic (1.72e-1)" "prognostic favorable (7.17e-11)" "unprognostic (5.00e-2)" "unprognostic (1.58e-1)" "unprognostic (2.59e-2)" "prognostic favorable (1.59e-4)" 10.9 16.3 7.7 13.1 8.1 35.4 10.5 9.3 10.4 10.6 8.3 12.7 13.4 11.8 8.1 14.6 12.2 10.2 20.6 11.0 6.5 12.3 15.7 11.7 17.8 8.7 7.0 19.3 30.2 16.7 9.1 10.8 8.6 12.8 10.3 20.2 24.4 13.0 52.0 12.1 13.0 11.6 6.4 15.3 14.6 15.5 8.2 12.0 16.4 42.4 12.6 11.5 9.2 8.3 11.5 17.2 11.8 14.0 12.8 14.5 11.3 16.5 16.9 20.9 12.8 17.0 16.8 15.2 9.6 18.4 27.8 9.2 16.3 8.7 13.4 9.0 12.5 15.5 10.5 12.9 15.6 17.9 24.3 10.5 18.2 13.9 16.1 14.4 9.8 13.9 17.6 23.9 15.8 11.0 21.8 15.3 14.0 15.3 26.4 14.0 24.1 8.0 19.1 15.9 19.2 13.8 14.2 12.6 16.6 9.5 19.0 26.6 15.3 13.2 10.2 16.1 22.9 21.6 19.5 19.7 10.9 9.7 13.7 0.7 1.3 6.9 2.7 1.7 1.9 2.5 1.7 2.6 1.2 1.7 2.3 1.7 4.4 1.5 2.1 1.3 2.0 1.2 7.7 8.1 9.3 10.4 11.0 6.5 8.7 7.0 8.6 6.4 8.2 8.3 7.1 9.6 15.0 7.2 9.0 4.6 2.7 3.3 0.6 27.1 12.4 8.0 12.7 4.3 9.1 7.3 31.3 3.6 14.2 10.6 5.9 4.5 2.9 8.6 9.0 6.4 7.2 2.1 5.0 9.3 2.9 8.0 8.2 8.7 9.5 6.3 4.2 16.7 5.7 40.4 5.2 9.5 4.1 8.8 4.2 4.8 16.8 7.0 7.2 1.9 8.1 10.4 6.2 5.0 3.7 7.9 7.8 12.8 5.1 5.8 8.7 7.6 7.1 38.3 0.0 12.4 5.2 6.1 4.5 3.6 5.8 4.4 10.1 12.5 6.9 5.4 TAF5L PAF65B ENSG00000135801 "TATA-box binding protein associated factor 5 like" O75529 1 229593121-229626047 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067941 Supported "Nuclear speckles,Cytoplasmic bodies" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nuclear speckles" "Cytoplasmic bodies" "HPA067941: AB_2685929" "unprognostic (3.41e-1)" "unprognostic (1.34e-1)" "unprognostic (3.39e-2)" "unprognostic (1.93e-1)" "unprognostic (7.46e-2)" "unprognostic (1.94e-1)" "unprognostic (2.91e-1)" "unprognostic (2.36e-1)" "unprognostic (1.63e-1)" "unprognostic (6.84e-2)" "unprognostic (5.17e-3)" "unprognostic (8.16e-3)" "unprognostic (1.91e-3)" "unprognostic (3.21e-1)" "unprognostic (2.99e-1)" "unprognostic (4.99e-2)" "unprognostic (3.11e-1)" 16.3 6.3 7.7 10.5 8.5 22.7 10.5 8.6 8.1 9.2 4.6 12.3 10.6 9.1 5.9 10.6 9.5 11.7 8.4 7.3 7.9 6.6 15.3 11.2 14.0 8.3 8.1 9.3 8.4 9.2 3.8 14.0 8.3 9.2 12.5 10.1 8.2 8.7 14.1 7.2 9.9 11.4 7.5 11.4 9.5 5.5 8.5 14.2 10.5 12.6 10.8 14.0 5.1 9.6 30.2 17.1 23.6 19.8 16.1 16.6 62.4 20.1 23.5 24.3 22.4 23.3 23.9 33.7 20.8 21.4 15.7 24.9 26.4 24.2 22.9 25.5 38.3 26.4 17.7 14.8 17.9 35.3 29.3 18.6 22.9 24.0 20.3 9.4 23.7 34.8 36.1 29.7 22.8 14.6 39.9 18.5 34.1 33.3 13.2 35.0 26.8 34.9 16.6 27.2 23.9 29.4 17.2 22.9 27.9 8.7 27.4 35.6 21.2 20.1 24.7 27.2 42.6 16.1 13.3 37.9 15.4 21.1 32.3 0.0 0.2 0.0 0.4 0.2 0.5 0.2 0.4 0.3 0.3 0.2 0.4 0.4 0.0 0.5 0.3 0.1 0.4 0.2 7.7 8.5 8.6 8.1 7.3 7.9 8.3 8.1 8.3 7.5 8.5 9.6 15.9 3.2 9.4 19.2 8.2 5.7 4.8 2.9 6.2 5.5 8.4 5.3 7.3 5.7 7.1 3.7 12.5 11.0 14.6 12.3 1.9 4.2 3.4 11.0 8.9 8.0 12.0 7.6 11.7 8.3 32.8 7.0 6.1 12.7 0.0 6.1 6.8 13.6 9.6 6.7 15.7 10.2 6.1 6.3 8.4 4.7 4.7 10.9 5.4 13.1 11.8 3.8 4.1 22.1 24.0 6.9 8.3 4.1 10.2 6.6 6.9 3.0 5.1 9.0 13.1 15.4 11.5 6.0 4.6 9.6 5.3 10.4 8.8 5.6 9.9 7.2 TAP2 "ABCB3, D6S217E, PSF2, RING11" ENSG00000204267 "Transporter 2, ATP binding cassette subfamily B member" Q03519 6 32821833-32838770 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity, Peptide transport, Protein transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "monocytes: 69.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HBEC3-KT: 61.4;U-251 MG: 52.0" HPA001312 Approved Supported "Nuclear speckles,Endoplasmic reticulum" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Endoplasmic reticulum" "Nuclear speckles" "HPA001312: AB_1080206" "unprognostic (2.95e-3)" "unprognostic (2.35e-1)" "unprognostic (3.77e-2)" "unprognostic (1.12e-1)" "unprognostic (1.39e-1)" "unprognostic (3.46e-1)" "unprognostic (8.04e-2)" "unprognostic (1.28e-2)" "unprognostic (1.68e-1)" "unprognostic (1.51e-2)" "prognostic unfavorable (1.51e-4)" "unprognostic (1.90e-1)" "prognostic unfavorable (5.22e-8)" "unprognostic (5.32e-1)" "unprognostic (4.17e-2)" "unprognostic (2.35e-1)" "unprognostic (4.71e-2)" 17.1 11.7 1.0 4.3 1.0 8.8 14.7 0.8 1.2 16.3 0.5 14.6 10.2 13.7 1.1 26.0 11.9 1.1 14.4 1.2 2.0 12.4 11.5 25.7 7.9 1.6 1.1 9.2 9.0 3.7 8.2 3.1 1.5 9.9 5.5 2.5 11.2 2.1 8.6 14.5 25.2 4.1 0.8 29.8 11.4 2.5 1.8 9.7 12.3 5.8 8.1 10.6 17.2 1.7 4.4 2.0 0.5 5.0 6.1 6.5 0.0 2.3 3.3 13.1 17.7 3.9 41.0 36.5 7.5 9.1 37.1 38.8 15.8 61.4 6.9 43.8 1.9 20.3 11.6 1.3 8.5 0.0 29.5 0.6 2.6 10.3 24.8 0.0 12.1 0.0 20.0 12.2 0.4 1.6 5.8 2.4 0.5 0.0 11.7 25.8 0.0 12.8 10.9 1.1 0.0 0.0 16.0 37.3 4.1 1.0 7.4 1.9 5.7 25.7 6.9 3.9 52.0 17.9 31.4 33.3 19.5 25.7 10.9 1.8 1.3 1.6 3.0 3.2 1.7 0.4 0.8 1.7 0.8 0.3 0.6 0.7 3.8 1.9 2.8 1.3 1.2 0.8 1.0 1.0 0.8 1.2 1.2 2.0 1.6 1.1 1.5 0.8 1.8 1.7 48.2 0.0 7.5 7.5 20.7 0.0 15.6 0.0 3.4 5.0 9.2 8.0 3.5 4.3 3.7 14.7 2.1 1.9 37.9 21.0 1.9 34.1 0.1 18.0 19.4 32.0 3.6 4.0 6.6 33.4 45.8 8.0 10.7 41.9 5.1 8.7 16.4 8.3 23.9 18.5 14.6 14.9 0.0 18.9 0.0 0.0 5.6 20.3 0.0 14.0 69.3 17.7 47.4 10.6 6.5 35.1 12.6 6.0 18.0 29.7 55.9 4.8 1.5 5.8 0.0 8.6 10.3 0.7 2.5 11.1 0.0 1.6 24.0 20.3 14.3 16.7 TARBP1 "TRM3, TRMT3, TRP-185" ENSG00000059588 "TAR (HIV-1) RNA binding protein 1" Q13395 1 234391313-234479179 "Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 209.4;Inhibitory neurons: 161.5;Oligodendrocyte precursor cells: 115.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020810, HPA024632" Uncertain Approved "Nuclear speckles" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 43: THP-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear speckles" "CAB020810: , HPA024632: AB_1857770" "unprognostic (3.64e-3)" "unprognostic (1.07e-1)" "unprognostic (3.75e-1)" "unprognostic (3.47e-1)" "unprognostic (8.26e-2)" "unprognostic (2.44e-3)" "unprognostic (8.45e-3)" "unprognostic (5.22e-3)" "unprognostic (3.72e-2)" "unprognostic (5.52e-2)" "unprognostic (2.56e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (5.14e-10)" "unprognostic (5.72e-2)" "unprognostic (1.82e-1)" "unprognostic (4.38e-2)" "unprognostic (4.27e-2)" 4.8 5.2 3.9 7.4 4.0 11.1 9.1 5.5 5.0 4.9 0.1 6.1 6.5 4.9 7.6 6.3 7.6 5.7 3.8 3.7 2.9 5.6 3.9 6.2 10.3 0.4 0.8 2.7 7.7 6.1 6.3 8.3 1.1 7.4 9.0 7.3 9.3 4.5 6.3 7.9 5.8 4.6 0.7 7.5 8.3 4.8 4.3 6.7 6.2 7.1 11.4 3.7 4.2 4.1 18.9 12.9 8.3 9.7 13.6 18.5 17.2 7.9 5.9 10.1 7.4 6.2 12.0 16.3 8.2 6.0 8.7 12.1 9.7 9.9 9.7 16.0 14.9 9.0 14.0 9.1 4.3 39.7 7.6 7.7 8.9 7.3 4.1 7.8 10.5 21.6 11.5 10.2 7.1 3.9 16.5 19.4 17.7 20.1 5.3 28.7 4.9 16.0 6.8 10.8 8.9 10.6 10.8 14.0 12.1 5.5 9.0 39.9 7.1 9.3 1.2 10.4 16.1 27.0 19.0 7.2 6.0 18.3 14.0 0.0 0.0 0.0 0.1 0.1 0.2 0.3 0.1 0.1 0.1 0.0 0.5 0.3 0.0 0.3 0.0 1.1 0.0 0.0 3.9 4.0 5.5 5.0 3.7 2.9 0.4 0.8 1.1 0.7 4.3 4.1 12.4 41.7 22.7 53.8 14.6 6.2 4.1 7.4 7.4 35.1 18.4 18.9 5.8 5.7 13.3 7.3 37.5 20.1 23.3 7.2 1.9 4.7 21.5 13.8 13.6 11.1 11.5 16.4 209.4 5.7 17.6 10.1 16.3 9.9 3.8 13.2 12.1 7.7 9.0 57.2 161.5 12.2 10.2 6.6 9.2 3.6 5.6 11.4 10.6 39.4 8.0 7.7 10.3 115.1 72.3 8.8 6.5 6.0 6.3 6.5 5.8 4.3 27.9 17.1 0.0 12.7 7.8 4.1 8.6 11.5 8.2 11.9 12.8 12.8 19.6 4.8 TATDN2 KIAA0218 ENSG00000157014 "TatD DNase domain containing 2" Q93075 3 10248023-10281218 "Predicted intracellular proteins" "Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" HPA036822 Approved Approved "Nuclear speckles" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" "Nuclear speckles" "HPA036822: AB_10671972" "unprognostic (4.51e-2)" "unprognostic (2.66e-3)" "unprognostic (2.75e-1)" "unprognostic (4.23e-2)" "unprognostic (9.88e-2)" "unprognostic (1.58e-2)" "unprognostic (2.57e-3)" "unprognostic (8.43e-2)" "unprognostic (3.78e-1)" "unprognostic (1.63e-1)" "prognostic favorable (4.66e-4)" "unprognostic (3.25e-1)" "unprognostic (1.87e-1)" "unprognostic (2.55e-2)" "unprognostic (1.70e-1)" "unprognostic (3.33e-1)" "unprognostic (2.48e-2)" 15.5 15.8 19.8 14.8 20.9 34.4 15.4 18.0 21.4 19.9 17.0 15.5 12.7 17.4 15.5 19.9 15.6 10.3 16.2 20.8 17.3 17.8 14.0 17.3 21.6 17.6 17.2 24.7 19.9 17.9 17.8 9.8 17.3 20.9 14.7 9.0 17.7 12.3 15.0 20.7 18.8 13.5 17.4 23.9 16.7 8.6 19.5 32.5 20.8 10.9 22.1 16.6 18.4 18.3 19.4 32.1 16.9 14.3 21.2 22.9 73.3 23.2 22.5 28.8 18.8 23.6 17.0 45.6 17.0 32.1 30.7 14.3 29.1 20.9 22.5 29.5 36.5 24.3 30.8 24.9 13.7 34.6 24.8 17.6 22.9 40.2 13.6 18.8 23.6 28.3 27.9 40.7 26.4 37.2 45.4 29.6 23.9 25.2 31.9 24.8 18.0 26.5 18.2 26.8 18.7 22.6 19.4 21.8 10.9 15.6 22.2 32.4 18.8 33.1 21.6 28.1 41.6 25.5 43.6 80.6 30.0 35.6 23.1 1.3 0.6 0.5 1.6 1.0 1.6 0.8 1.4 1.3 0.5 1.4 1.4 2.1 0.5 0.9 0.5 1.3 1.7 0.9 19.8 20.9 18.0 21.4 20.8 17.3 17.6 17.2 17.3 17.4 19.5 18.3 6.3 6.4 11.0 4.9 8.2 12.6 4.6 4.8 9.1 4.4 9.4 6.3 6.9 7.2 4.3 11.0 6.2 3.8 9.3 12.7 1.9 5.1 2.0 4.1 7.0 7.9 16.8 6.1 8.8 9.2 4.0 6.8 5.1 5.9 5.1 9.1 7.9 10.2 10.3 5.0 5.9 8.7 2.0 15.6 21.0 1.8 7.2 9.1 14.2 6.5 9.0 5.2 18.6 4.5 5.0 8.6 3.1 7.5 8.8 9.3 8.0 5.4 2.4 2.8 6.6 5.8 4.7 2.1 5.6 6.4 12.4 2.5 10.7 8.7 10.8 7.1 TBC1D12 KIAA0608 ENSG00000108239 "TBC1 domain family member 12" O60347 10 94402541-94536332 "Cancer-related genes, Predicted intracellular proteins" "GTPase activation" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 46.1" "Cell type enhanced" "Detected in many" "Microglial cells: 110.5;Oligodendrocytes: 397.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038277, HPA038645" Uncertain Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 39: CACO-2 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Nuclear speckles" "HPA038277: AB_10672584, HPA038645: AB_10672650" "unprognostic (7.23e-3)" "unprognostic (1.58e-2)" "prognostic favorable (1.79e-5)" "unprognostic (7.83e-2)" "unprognostic (1.76e-1)" "unprognostic (4.91e-2)" "unprognostic (1.21e-2)" "unprognostic (7.34e-2)" "unprognostic (6.56e-2)" "unprognostic (9.43e-2)" "unprognostic (1.81e-1)" "unprognostic (1.59e-1)" "unprognostic (2.27e-2)" "unprognostic (9.43e-2)" "unprognostic (3.71e-1)" "unprognostic (1.29e-1)" "unprognostic (1.12e-1)" 5.8 3.6 13.5 3.1 26.5 1.1 5.6 28.3 16.0 4.6 8.2 6.1 4.5 4.1 2.8 3.3 3.8 3.6 3.8 12.4 17.8 4.0 3.7 4.7 2.5 40.2 26.7 3.9 4.6 13.3 2.6 5.7 35.8 4.1 6.8 7.0 3.2 4.3 4.1 4.9 5.1 4.3 25.1 4.9 3.6 8.4 23.0 1.3 3.3 4.1 2.6 4.6 4.1 46.1 7.3 3.2 4.1 6.1 5.6 6.8 5.4 4.6 9.5 5.1 4.7 12.8 3.1 0.0 2.7 6.8 4.9 4.0 4.9 3.4 6.5 0.0 5.7 2.3 2.9 4.1 4.2 0.0 1.8 4.6 4.3 5.3 6.9 8.6 5.5 0.0 3.4 7.4 8.2 4.0 0.0 0.0 1.3 5.2 3.3 0.0 5.3 3.9 4.6 3.2 1.7 4.1 4.6 4.0 3.9 3.7 8.6 4.4 5.4 3.5 4.8 5.7 3.7 5.1 5.3 0.0 3.5 0.0 1.9 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 26.5 28.3 16.0 12.4 17.8 40.2 26.7 35.8 25.1 23.0 46.1 11.0 9.6 5.3 34.9 7.6 19.5 6.5 2.9 10.8 17.5 10.6 9.1 6.5 4.3 4.3 9.2 10.4 19.4 0.6 18.1 0.0 5.8 22.6 7.6 9.5 13.7 8.4 5.2 46.8 5.1 13.4 23.8 13.7 10.3 5.7 3.5 8.9 4.8 19.1 8.4 66.7 8.7 4.1 23.6 25.9 9.2 8.4 20.9 16.0 110.5 11.7 8.9 1.0 60.8 397.2 7.6 13.2 10.5 12.0 11.7 11.7 5.9 4.0 28.0 13.1 11.7 12.0 64.3 13.5 11.4 19.2 24.4 1.5 6.3 11.8 10.3 TBC1D8 "AD3, GRAMD8, HBLP1, VRP" ENSG00000204634 "TBC1 domain family member 8" O95759 2 101007228-101252866 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 43.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 30.1;non-classical monocyte: 38.2" "Lineage enriched" "Detected in many" 5 "monocytes: 38.2" "Cell line enhanced" "Detected in many" "ASC diff: 82.9;ASC TERT1: 57.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015211, HPA037496" Uncertain Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Nuclear speckles" "CAB015211: , HPA037496: AB_2675507" "unprognostic (1.82e-1)" "unprognostic (2.04e-1)" "prognostic unfavorable (6.73e-4)" "unprognostic (4.25e-3)" "unprognostic (3.98e-1)" "unprognostic (2.12e-2)" "unprognostic (1.08e-2)" "unprognostic (2.74e-1)" "unprognostic (5.80e-2)" "unprognostic (2.38e-1)" "unprognostic (8.53e-2)" "unprognostic (1.82e-1)" "unprognostic (2.25e-2)" "unprognostic (8.02e-2)" "unprognostic (1.26e-1)" "unprognostic (6.73e-2)" "unprognostic (7.98e-3)" 17.3 6.3 4.7 8.9 4.4 12.7 21.8 8.7 5.0 14.4 8.3 9.0 7.1 10.6 7.8 15.4 19.9 18.1 38.6 5.1 6.3 17.0 24.8 23.2 7.2 6.8 5.3 8.4 34.3 17.5 13.0 3.1 6.7 44.0 6.0 6.5 19.0 30.3 83.7 28.1 28.7 6.9 4.3 14.5 27.2 18.1 5.9 6.4 9.6 79.7 6.8 13.1 17.5 4.1 5.1 30.1 2.6 8.6 82.9 57.8 24.4 3.1 51.8 2.1 2.6 10.8 8.0 2.6 27.1 2.3 42.5 15.5 5.0 23.5 1.4 1.5 4.6 1.5 11.1 37.7 5.7 0.3 26.0 27.4 21.8 2.8 21.6 1.7 30.2 4.5 0.7 2.6 2.7 13.3 2.8 15.8 6.7 3.6 32.3 6.4 7.5 0.6 17.0 32.3 18.7 9.2 4.2 7.4 10.8 4.0 2.1 23.1 26.0 1.3 4.5 4.4 2.1 5.0 0.4 0.2 10.9 7.7 8.0 0.0 9.7 0.4 0.2 30.1 0.3 0.4 0.3 0.2 5.0 1.5 0.6 0.4 0.3 0.0 38.2 7.2 0.2 4.1 4.7 4.4 8.7 5.0 5.1 6.3 6.8 5.3 6.7 4.3 5.9 4.1 4.3 3.2 4.6 10.7 2.8 4.1 38.3 7.2 23.9 6.4 15.0 3.9 12.2 18.6 14.4 5.5 4.2 4.6 4.8 1.1 0.0 8.2 6.0 42.6 4.7 9.8 3.0 0.8 43.5 3.0 2.8 4.3 31.6 23.7 7.0 0.9 11.7 5.6 3.7 1.7 42.8 2.2 10.2 13.8 17.7 10.9 3.1 27.7 5.4 22.5 28.1 1.0 0.0 23.6 6.5 2.6 2.4 1.9 1.4 35.0 4.8 1.2 31.9 3.7 6.6 24.7 4.3 3.6 4.0 29.8 6.3 3.4 1.6 2.7 1.1 29.7 TBX19 "dj747L4.1, TPIT" ENSG00000143178 "T-box transcription factor 19" O60806 1 168280877-168314426 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "pituitary gland: 50.2" "Cell type enhanced" "Detected in many" "Langerhans cells: 8.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 5.5;HDLM-2: 5.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005800, HPA072686" Enhanced Approved "Nuclear speckles" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 41: Macrophages - Immune response" "Nuclear speckles" "HPA005800: AB_1080219, HPA072686: AB_2732209" "unprognostic (2.47e-1)" "unprognostic (1.20e-2)" "unprognostic (8.76e-4)" "unprognostic (1.43e-2)" "unprognostic (3.09e-2)" "unprognostic (8.36e-2)" "unprognostic (7.14e-7)" "unprognostic (1.83e-1)" "unprognostic (2.04e-1)" "unprognostic (5.58e-2)" "unprognostic (9.78e-3)" "unprognostic (1.28e-1)" "prognostic unfavorable (4.55e-9)" "unprognostic (8.57e-2)" "unprognostic (6.63e-2)" "unprognostic (9.06e-2)" "unprognostic (1.05e-2)" 1.8 0.8 1.0 0.8 1.2 0.7 1.8 0.8 1.3 2.9 1.0 2.5 0.8 5.0 0.8 1.6 2.7 1.2 1.1 1.1 2.0 1.8 1.1 2.4 1.7 1.5 1.1 3.7 1.1 0.5 50.2 0.6 1.2 2.2 1.0 0.4 1.8 1.0 0.8 2.5 1.6 2.1 1.0 2.3 1.1 1.0 1.5 1.6 1.3 0.8 1.1 1.5 2.1 1.2 1.0 0.0 0.8 3.1 1.4 0.6 1.0 1.6 0.9 0.5 0.8 1.4 1.0 0.8 1.7 0.6 0.8 5.5 0.4 0.4 0.8 5.1 0.7 0.1 1.1 0.4 1.5 1.6 2.0 1.2 1.4 0.2 0.8 1.3 0.7 0.3 1.1 1.3 0.7 0.2 0.8 1.3 0.2 3.3 0.5 1.3 0.4 0.3 1.2 0.4 1.1 1.6 0.9 0.7 1.0 1.3 0.2 1.3 1.2 0.5 1.3 1.1 1.7 1.0 0.8 0.6 0.1 0.4 1.6 0.2 0.7 0.4 1.1 0.5 0.5 0.4 0.8 0.7 0.7 0.5 0.5 0.5 1.0 0.9 1.0 2.4 0.8 0.6 1.0 1.2 0.8 1.3 1.1 2.0 1.5 1.1 1.2 1.0 1.5 1.2 1.4 0.0 0.5 2.3 1.4 2.7 1.3 1.2 2.2 0.0 3.1 3.0 0.4 0.0 0.6 0.0 0.0 0.1 6.1 2.6 0.0 0.6 0.6 3.2 1.8 2.5 1.2 0.8 0.7 0.4 0.4 2.5 0.0 5.6 4.5 1.8 0.4 0.7 1.3 0.0 0.5 0.9 2.0 2.8 8.9 0.7 3.4 4.2 0.0 6.5 3.9 0.4 6.2 0.5 3.1 1.9 0.6 2.6 1.1 4.3 0.7 0.6 1.2 0.0 0.0 0.7 0.9 1.0 1.1 1.9 3.3 0.1 1.6 0.9 0.9 2.7 TBXA2R ENSG00000006638 "Thromboxane A2 receptor" P21731 19 3594507-3606875 "Disease related genes, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 6 "Adipocytes: 10.8;Endothelial cells: 8.7;Hepatic stellate cells: 30.7;Macrophages: 19.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 11.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HeLa: 9.5;U-2197: 6.8;U-937: 6.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA077366 Supported "Nuclear speckles,Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane" "Nuclear speckles" "HPA077366: AB_2686836" "unprognostic (1.59e-1)" "unprognostic (3.86e-2)" "unprognostic (1.21e-2)" "unprognostic (1.74e-1)" "unprognostic (8.97e-2)" "unprognostic (4.19e-2)" "unprognostic (1.52e-2)" "unprognostic (2.17e-3)" "unprognostic (8.41e-2)" "unprognostic (6.25e-2)" "prognostic favorable (7.17e-4)" "unprognostic (3.89e-2)" "prognostic unfavorable (1.45e-4)" "unprognostic (4.32e-2)" "unprognostic (9.63e-2)" "unprognostic (1.76e-1)" "unprognostic (2.02e-1)" 3.8 8.7 1.3 1.6 1.1 1.0 1.9 1.8 1.3 5.4 1.3 2.3 0.8 5.2 0.4 1.7 3.3 1.0 5.0 1.1 1.1 6.3 6.1 4.4 1.0 1.7 1.3 2.0 0.9 1.2 1.0 3.2 1.5 2.5 0.4 0.5 0.6 1.4 1.4 1.1 3.2 1.8 1.1 7.0 2.5 0.6 1.4 0.3 2.6 0.6 0.3 2.6 3.6 2.1 0.2 0.2 0.3 3.4 0.7 1.7 0.5 2.4 0.6 1.8 1.4 0.1 0.3 0.1 3.5 1.0 1.8 0.2 0.7 0.0 0.7 0.2 0.8 2.3 9.5 0.2 0.9 0.2 4.1 0.8 0.0 2.4 0.0 1.4 0.7 0.1 3.8 0.4 0.3 0.1 0.2 1.2 0.3 0.1 2.1 0.1 0.0 0.1 0.0 0.1 0.1 1.3 0.2 0.4 0.1 0.3 1.5 4.2 2.1 3.8 0.8 6.8 2.3 0.2 0.3 0.2 3.1 6.1 0.9 3.7 0.4 0.4 2.5 0.2 0.3 2.0 0.7 2.2 0.1 11.1 4.3 9.4 4.1 3.3 0.3 0.3 0.2 4.0 1.3 1.1 1.8 1.3 1.1 1.1 1.7 1.3 1.5 1.1 1.4 2.1 10.8 0.0 0.0 0.0 2.6 0.5 0.1 0.0 0.0 0.3 0.1 0.1 1.3 0.0 0.0 1.8 0.0 0.1 0.4 0.0 0.0 0.1 0.0 0.1 0.6 8.7 0.0 0.0 0.3 0.0 0.2 2.3 0.0 0.1 0.0 0.2 30.7 0.6 0.9 0.0 0.9 0.0 0.0 1.0 0.3 0.0 0.3 19.2 1.8 1.9 0.3 0.5 1.0 0.5 0.4 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 2.5 0.4 1.9 0.1 0.6 0.1 0.8 0.4 0.1 0.0 TCEAL2 "my048, MY0876G05, WEX1" ENSG00000184905 "Transcription elongation factor A like 2" Q9H3H9 X 102125679-102140426 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 162.0;pituitary gland: 189.9" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 73.5;Bipolar cells: 141.8;Distal tubular cells: 70.5;Granulosa cells: 62.4;Horizontal cells: 97.6;Muller glia cells: 215.8" "Cancer enhanced" "Detected in many" "glioma: 22.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HAP1: 5.7;SCLC-21H: 6.2;U-2 OS: 11.0" HPA076317 Approved "Nuclear speckles,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" "Nuclear speckles" Cytosol "HPA076317: AB_2686794" "unprognostic (2.34e-3)" "unprognostic (1.35e-2)" "unprognostic (7.59e-3)" "unprognostic (3.84e-3)" "unprognostic (2.07e-1)" "unprognostic (4.57e-2)" "unprognostic (4.27e-2)" "unprognostic (2.80e-2)" "unprognostic (3.47e-1)" "unprognostic (3.26e-1)" "unprognostic (7.07e-3)" "unprognostic (1.43e-1)" "unprognostic (1.56e-2)" "unprognostic (1.73e-2)" "unprognostic (7.76e-2)" "unprognostic (1.04e-1)" "unprognostic (4.11e-3)" 8.1 25.9 115.4 2.3 114.2 0.0 5.9 114.3 162.0 25.5 85.6 48.6 3.0 34.7 10.3 5.9 30.0 7.6 28.0 113.2 123.5 19.2 0.6 10.2 0.7 116.4 119.0 86.9 5.4 25.0 189.9 0.0 112.1 33.6 3.7 62.3 23.7 27.6 0.7 3.4 11.5 17.8 103.5 4.7 24.7 42.2 111.0 1.4 45.9 2.1 1.5 12.5 16.5 121.9 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.3 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 1.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 11.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 115.4 114.2 114.3 162.0 113.2 123.5 116.4 119.0 112.1 103.5 111.0 121.9 0.6 6.4 16.3 12.7 0.1 1.9 73.5 0.0 6.8 141.8 0.7 9.7 8.7 4.3 12.4 31.3 6.2 0.1 0.0 0.0 70.5 0.2 3.8 0.2 0.4 5.7 0.0 0.0 30.1 0.4 0.1 11.1 0.0 0.1 2.5 62.4 7.1 0.3 0.0 97.6 30.9 0.0 0.0 0.0 1.1 9.6 6.5 0.9 7.2 4.7 0.6 215.8 0.0 16.6 8.7 1.0 0.0 5.7 0.1 47.3 0.0 0.7 0.0 45.4 6.6 46.3 9.6 4.6 3.6 0.2 1.3 0.0 0.7 0.4 0.0 7.6 TCEANC MGC17403 ENSG00000176896 "Transcription elongation factor A N-terminal and central domain containing" Q8N8B7 X 13653189-13681964 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythroid cells: 19.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000337, HPA001013" Uncertain Approved "Nuclear speckles" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 6: Erythroid cells - Oxygen transport" "Nuclear speckles" "HPA000337: , HPA001013: AB_1079371" "unprognostic (1.44e-1)" "unprognostic (2.21e-3)" "unprognostic (1.74e-2)" "unprognostic (4.45e-2)" "unprognostic (2.21e-3)" "unprognostic (2.29e-3)" "unprognostic (4.03e-2)" "unprognostic (4.29e-6)" "unprognostic (3.82e-2)" "unprognostic (2.26e-2)" "unprognostic (1.63e-5)" "unprognostic (1.68e-1)" "unprognostic (1.25e-3)" "unprognostic (1.19e-1)" "unprognostic (1.38e-1)" "unprognostic (5.10e-3)" "unprognostic (1.11e-4)" 1.5 1.2 1.3 1.0 1.4 4.5 2.5 2.0 1.8 1.5 1.2 1.2 1.1 1.5 3.0 0.8 1.8 1.0 1.5 1.4 1.4 1.5 1.7 1.7 2.7 1.5 1.4 2.5 1.5 1.2 1.3 1.2 1.5 1.5 1.5 2.8 1.8 1.2 1.7 1.5 1.4 1.5 1.3 2.5 1.2 1.0 1.6 2.9 2.0 1.5 2.0 1.1 1.1 1.9 0.4 1.1 1.2 2.1 2.5 3.0 0.4 0.3 1.0 1.0 0.4 0.4 0.8 1.3 1.1 0.8 0.6 0.6 1.1 0.6 0.2 1.4 1.5 0.7 0.6 0.6 1.4 1.1 1.3 2.6 1.0 0.6 4.2 1.5 0.3 1.3 1.4 2.2 1.4 0.9 1.8 1.1 1.6 0.6 0.3 1.4 1.1 2.8 0.5 0.7 1.2 1.1 1.1 1.2 1.6 1.5 1.2 1.0 0.5 0.9 0.4 0.8 0.1 1.8 1.1 1.0 1.2 0.6 0.4 7.2 1.6 4.2 2.6 1.4 3.0 3.5 2.8 3.5 1.3 3.6 3.4 3.1 2.1 1.6 1.5 2.3 3.7 1.9 1.3 1.4 2.0 1.8 1.4 1.4 1.5 1.4 1.5 1.3 1.6 1.9 2.9 0.0 1.1 1.6 3.8 0.3 1.0 1.2 1.8 3.5 2.3 2.0 2.6 1.5 2.3 3.7 2.1 2.2 7.3 1.3 3.9 1.5 0.0 2.2 2.6 1.5 2.4 19.0 1.7 0.9 0.8 1.8 1.1 2.0 5.1 2.1 1.8 3.9 2.0 1.7 2.2 2.5 2.0 2.8 2.0 0.2 3.4 1.8 0.0 2.8 3.1 4.9 6.2 0.5 2.5 0.5 1.8 2.2 7.3 1.2 2.7 3.2 2.0 2.3 0.0 1.7 2.6 1.1 1.2 0.9 0.3 3.3 4.8 2.1 1.3 0.9 TCF12 "bHLHb20, HEB, HsT17266, HTF4, p64" ENSG00000140262 "Transcription factor 12" Q99081 15 56918623-57299281 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 319.8;Microglial cells: 440.3;Oligodendrocyte precursor cells: 618.3;Oligodendrocytes: 1512.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004432, HPA065827" Approved Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Nuclear speckles" "CAB004432: AB_671267, HPA065827: AB_2685564" "unprognostic (1.19e-1)" "unprognostic (1.11e-1)" "unprognostic (8.26e-2)" "unprognostic (1.65e-1)" "unprognostic (2.07e-3)" "unprognostic (1.11e-1)" "unprognostic (6.63e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (8.89e-4)" "unprognostic (7.83e-2)" "unprognostic (7.26e-3)" "unprognostic (5.57e-3)" "prognostic unfavorable (5.24e-5)" "unprognostic (2.03e-1)" "unprognostic (2.93e-1)" "unprognostic (3.15e-2)" "unprognostic (1.41e-1)" 26.1 21.5 29.2 23.4 45.5 21.2 29.5 37.1 34.0 75.6 17.2 26.7 28.4 47.9 24.3 26.6 46.3 37.1 21.8 30.5 32.6 28.4 25.0 28.9 26.0 43.1 39.3 43.3 19.7 44.0 11.5 33.4 38.3 32.0 30.3 29.4 23.3 28.3 20.5 21.3 28.4 44.1 34.5 25.0 25.5 27.4 35.5 133.0 29.0 26.6 28.1 31.2 22.4 55.7 25.4 50.8 204.5 70.6 90.0 79.0 36.1 52.2 89.6 45.1 58.9 34.0 20.3 35.5 42.3 78.3 33.4 30.4 84.3 37.3 56.7 47.5 29.8 71.7 52.7 40.4 62.4 46.1 36.1 69.4 66.2 42.9 112.2 60.1 81.0 163.0 81.7 46.8 61.8 9.5 109.4 25.0 57.5 26.4 20.9 143.2 234.9 33.9 61.5 53.1 43.6 121.2 58.7 21.0 52.0 65.3 33.6 93.9 63.2 75.5 57.5 32.2 78.2 24.6 49.7 59.4 40.8 86.3 90.9 27.4 13.8 11.3 17.4 17.9 14.3 13.4 14.0 16.5 20.0 14.7 16.2 14.8 1.5 16.8 26.3 8.4 23.0 14.1 29.2 45.5 37.1 34.0 30.5 32.6 43.1 39.3 38.3 34.5 35.5 55.7 35.5 54.5 19.6 212.9 37.7 26.6 20.6 14.2 44.9 13.8 24.0 20.4 19.3 14.3 21.2 16.5 35.5 10.4 20.6 17.0 13.7 16.0 23.7 25.9 148.0 38.2 9.0 34.9 117.7 11.8 15.5 42.3 52.0 33.3 23.4 26.9 25.7 18.2 27.5 13.5 319.8 16.8 10.2 38.1 30.0 19.9 25.7 33.0 14.2 440.3 17.4 29.0 18.6 618.3 1512.7 15.9 18.4 34.6 29.1 23.4 20.0 15.3 15.9 23.3 46.0 39.9 36.5 22.2 15.0 33.6 33.8 13.0 28.4 16.5 20.1 18.2 TCF15 "bHLHa40, EC2, PARAXIS" ENSG00000125878 "Transcription factor 15" Q12870 20 603797-610398 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "heart muscle: 27.8;skeletal muscle: 13.2;tongue: 9.1" "Cell type enriched" "Detected in some" 6 "Adipocytes: 260.0" "Cancer enhanced" "Detected in many" "testis cancer: 3.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HEL: 10.6;HMC-1: 16.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA050998, HPA060221" Approved Supported "Nuclear speckles" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles" "HPA050998: AB_2681302, HPA060221: AB_2684225" "unprognostic (2.12e-2)" "unprognostic (1.96e-2)" "unprognostic (1.58e-2)" "unprognostic (3.55e-2)" "unprognostic (1.29e-1)" "unprognostic (4.62e-2)" "unprognostic (5.57e-2)" "unprognostic (2.33e-1)" "unprognostic (2.81e-1)" "prognostic unfavorable (3.25e-4)" "unprognostic (1.52e-1)" "unprognostic (9.43e-2)" "unprognostic (1.27e-3)" "unprognostic (7.21e-2)" "unprognostic (8.56e-2)" "unprognostic (5.11e-1)" "unprognostic (6.99e-2)" 7.0 0.6 1.3 0.1 1.2 0.0 4.6 1.2 1.4 0.2 0.9 1.6 0.1 0.8 0.0 0.3 0.4 0.1 27.8 1.1 1.2 1.5 0.2 0.6 0.1 1.3 1.3 0.2 0.3 0.1 0.4 3.3 1.4 0.3 0.0 0.0 0.6 0.0 13.2 0.2 0.5 0.2 1.3 0.0 0.6 2.0 1.3 0.0 0.5 9.1 0.0 0.9 0.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 1.5 0.0 0.0 0.0 2.9 10.6 0.0 0.0 0.0 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.7 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.1 0.0 0.0 1.7 0.0 0.0 0.0 1.5 0.0 1.3 0.0 3.0 0.0 1.4 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.2 1.2 1.4 1.1 1.2 1.3 1.3 1.4 1.3 1.3 1.2 260.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.6 0.5 0.6 1.0 15.6 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.7 0.2 0.2 41.2 0.0 0.0 0.0 0.0 0.1 2.2 0.0 0.6 0.0 0.1 7.1 0.0 0.1 1.7 0.5 0.0 0.0 0.0 0.4 0.2 0.0 0.5 0.0 2.8 0.0 0.1 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 13.1 3.7 23.3 2.3 0.6 0.0 0.0 0.0 0.2 0.5 0.0 0.0 TCF23 "bHLHa24, OUT" ENSG00000163792 "Transcription factor 23" Q7RTU1 2 27149004-27156974 "Predicted intracellular proteins, Transcription factors" "Differentiation, Myogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "endometrium 1: 51.2;fallopian tube: 24.6;ovary: 18.5;smooth muscle: 20.4" "Cell type enhanced" "Detected in some" "Leydig cells: 10.5;Peritubular cells: 29.0;Sertoli cells: 52.6" "Cancer enhanced" "Detected in some" "ovarian cancer: 0.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 1.6" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in single" 12 "THP-1: 3.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA044596 Approved "Nuclear speckles" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Nuclear speckles" "HPA044596: AB_10797258" "unprognostic (1.04e-1)" "unprognostic (2.47e-3)" "unprognostic (1.70e-2)" "unprognostic (4.21e-2)" "unprognostic (3.65e-2)" "unprognostic (2.68e-2)" "unprognostic (1.70e-2)" "unprognostic (4.07e-2)" "unprognostic (3.21e-1)" "unprognostic (1.74e-2)" "unprognostic (4.08e-2)" "unprognostic (8.58e-2)" "unprognostic (2.41e-5)" "unprognostic (7.58e-3)" "unprognostic (3.01e-1)" "unprognostic (8.58e-4)" "unprognostic (2.64e-2)" 0.4 0.0 0.2 0.0 0.2 0.2 0.0 0.5 0.4 4.6 0.2 0.2 0.1 51.2 5.8 0.0 24.6 0.7 0.0 0.3 0.2 0.0 0.0 0.0 0.1 0.1 0.1 18.5 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.5 0.2 0.1 0.1 20.4 0.0 2.3 0.1 2.6 0.2 0.0 0.0 0.0 0.0 0.2 2.9 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.3 0.2 0.2 0.1 0.2 0.3 0.3 0.2 0.0 0.4 0.3 0.2 1.1 0.3 0.1 0.4 0.1 0.0 0.2 0.2 0.5 0.4 0.3 0.2 0.1 0.1 0.3 0.0 0.2 0.5 0.1 0.0 2.2 0.0 0.3 0.0 0.6 0.0 0.0 0.4 0.3 0.3 0.7 0.0 0.6 0.0 2.1 0.0 0.2 0.1 0.0 0.0 1.7 0.2 1.2 0.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.3 1.3 0.1 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.8 10.5 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 29.0 0.0 0.7 0.0 0.1 0.0 0.6 52.6 1.0 1.5 0.3 0.2 0.0 0.0 0.1 0.1 0.2 0.0 0.6 TCP11L2 MGC40368 ENSG00000166046 "T-complex 11 like 2" Q8N4U5 12 106301929-106347003 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 98.8;choroid plexus: 79.4" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 111.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 67.0" "Lineage enriched" "Detected in all" 5 "granulocytes: 67.0" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 25.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039483, HPA042188" Uncertain Supported "Nuclear speckles" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nuclear speckles" "HPA039483: AB_10795291, HPA042188: AB_10794415" "unprognostic (1.41e-1)" "unprognostic (3.17e-1)" "unprognostic (1.24e-1)" "unprognostic (8.15e-2)" "unprognostic (1.97e-1)" "prognostic favorable (9.52e-4)" "unprognostic (3.87e-3)" "unprognostic (2.43e-1)" "unprognostic (2.11e-1)" "unprognostic (9.05e-3)" "unprognostic (5.44e-2)" "unprognostic (1.33e-1)" "unprognostic (1.22e-2)" "unprognostic (1.24e-1)" "unprognostic (1.28e-1)" "unprognostic (5.02e-2)" "unprognostic (3.67e-1)" 11.5 8.8 16.4 7.9 43.0 30.3 10.3 32.6 24.5 9.2 79.4 7.7 7.5 10.0 4.2 22.9 13.1 9.5 22.6 12.9 22.4 6.7 6.5 16.7 10.2 46.6 33.2 9.0 6.0 10.2 4.8 14.5 43.3 6.7 9.0 10.3 12.1 6.5 17.9 13.9 9.8 8.2 28.4 11.7 12.1 10.6 30.8 13.6 11.6 23.0 16.8 8.5 9.3 98.8 3.3 8.1 1.1 2.3 10.6 12.2 5.0 2.1 10.2 1.3 3.2 1.3 4.3 1.1 3.2 8.1 3.0 15.2 1.0 4.5 2.3 1.7 3.3 0.7 3.4 5.1 10.4 0.3 2.1 15.4 10.2 1.6 7.6 25.1 7.5 5.9 2.0 1.5 1.9 2.4 2.0 1.7 1.4 4.4 5.0 1.0 0.3 3.8 10.1 15.2 5.0 3.6 5.5 1.7 6.0 8.4 4.6 0.3 5.7 1.9 1.6 2.9 0.5 10.0 0.8 3.8 5.3 0.3 1.0 29.6 6.9 11.0 4.8 3.1 3.6 12.4 9.9 5.4 1.7 10.6 12.2 8.3 67.0 4.3 5.3 1.2 12.3 3.8 16.4 43.0 32.6 24.5 12.9 22.4 46.6 33.2 43.3 28.4 30.8 98.8 12.6 12.8 14.4 15.0 23.1 1.1 3.4 4.4 5.7 8.1 3.5 5.5 10.5 0.0 8.6 3.7 22.9 1.5 13.4 4.2 1.9 3.6 6.3 28.6 7.3 12.1 4.2 33.7 7.7 2.6 0.8 10.5 11.2 20.5 2.5 4.3 6.1 1.5 1.2 21.9 23.9 5.0 2.0 3.1 2.0 4.5 5.9 5.2 3.6 12.2 8.0 3.1 10.3 9.0 111.0 3.7 4.8 2.6 9.9 4.0 5.9 1.2 16.7 13.4 13.1 11.8 7.2 4.3 3.0 6.3 2.6 15.1 12.4 8.0 1.2 8.7 TEPSIN "C17orf56, ENTHD2, FLJ31528" ENSG00000167302 "TEPSIN adaptor related protein complex 4 accessory protein" Q96N21 17 81228277-81239091 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 9.6;Cytotrophoblasts: 9.9;Syncytiotrophoblasts: 10.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063410 Approved "Nuclear membrane,Nuclear speckles,Golgi apparatus" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" "Nuclear membrane, Nuclear speckles, Golgi apparatus" "HPA063410: AB_2685008" "unprognostic (6.90e-3)" "unprognostic (1.03e-2)" "unprognostic (4.26e-2)" "unprognostic (3.64e-2)" "unprognostic (1.00e-1)" "prognostic favorable (9.96e-4)" "unprognostic (1.16e-2)" "unprognostic (4.85e-2)" "unprognostic (8.52e-2)" "unprognostic (2.29e-1)" "prognostic favorable (6.95e-4)" "unprognostic (4.99e-2)" "prognostic unfavorable (7.31e-8)" "unprognostic (1.65e-1)" "unprognostic (3.01e-1)" "unprognostic (3.58e-1)" "unprognostic (3.16e-3)" 11.4 12.1 8.3 7.4 8.5 13.0 11.3 8.4 12.8 12.9 9.1 14.2 10.8 11.2 4.0 13.3 11.5 4.3 10.2 8.3 8.1 16.6 17.7 12.0 11.0 9.4 8.5 9.3 15.8 3.3 11.4 5.3 8.9 15.3 4.0 1.6 12.0 3.0 10.0 14.6 19.7 4.4 8.3 28.6 15.6 13.3 9.1 10.3 16.0 3.2 5.8 13.5 11.8 8.8 9.5 14.2 5.1 8.6 3.5 5.7 10.0 8.2 4.7 8.5 7.6 9.1 6.8 6.9 4.5 5.5 8.0 11.8 5.3 7.3 3.8 4.1 18.7 5.7 8.1 13.0 5.4 6.0 12.8 3.4 9.1 3.8 4.2 5.9 13.4 9.7 6.7 6.7 5.3 8.4 11.2 15.7 5.7 7.5 11.6 6.9 7.1 7.4 3.3 6.1 6.7 8.5 9.7 11.1 11.5 9.9 9.1 11.3 8.0 11.2 6.6 8.5 8.3 9.4 6.5 5.5 8.3 5.3 5.7 2.4 1.2 4.0 0.8 1.6 0.5 1.2 0.5 0.6 1.3 1.8 0.3 0.4 2.1 0.4 1.0 1.4 0.8 0.8 8.3 8.5 8.4 12.8 8.3 8.1 9.4 8.5 8.9 8.3 9.1 8.8 8.6 9.6 5.5 0.0 2.9 0.0 0.0 0.0 0.0 0.0 6.9 7.1 0.0 0.0 1.3 1.8 0.0 9.9 8.8 0.0 0.0 4.7 0.0 3.2 5.8 3.0 0.0 0.0 0.0 5.3 7.2 2.5 0.0 6.2 6.3 8.6 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 8.8 0.0 0.0 0.0 0.0 6.0 0.0 0.0 3.3 0.0 0.0 2.3 2.2 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 10.5 3.9 5.1 0.0 0.0 TERT "EST2, hEST2, TCS1, TP2, TRT" ENSG00000164362 "Telomerase reverse transcriptase" O14746 5 1253147-1295068 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "DNA-binding, Nucleotidyltransferase, Ribonucleoprotein, RNA-directed DNA polymerase, Transferase" "Cancer-related genes, Disease variant, Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.4;Intestinal goblet cells: 1.0;Plasma cells: 2.8;Spermatocytes: 1.5;Spermatogonia: 4.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 438.0;fHDF/TERT166: 429.4;HBEC3-KT: 929.2;hTEC/SVTERT24-B: 560.1;LHCN-M2: 252.2;TIME: 799.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA054641, HPA065897" Supported Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm "Nuclear speckles, Cytosol" "HPA054641: AB_2682554, HPA065897: AB_2685576" "unprognostic (1.21e-2)" "unprognostic (2.88e-2)" "unprognostic (1.24e-3)" "unprognostic (1.53e-1)" "unprognostic (1.43e-3)" "unprognostic (6.42e-3)" "unprognostic (1.85e-2)" "unprognostic (2.21e-1)" "unprognostic (6.91e-2)" "unprognostic (1.89e-1)" "unprognostic (3.59e-1)" "unprognostic (9.16e-4)" "unprognostic (8.84e-11)" "unprognostic (1.92e-1)" "unprognostic (2.15e-1)" "unprognostic (3.35e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 213.2 438.0 3.2 0.0 173.9 31.7 59.4 0.3 0.1 3.0 0.2 429.4 0.1 0.1 1.0 929.2 29.1 0.0 1.7 0.1 0.0 0.4 0.1 0.5 1.2 0.0 22.9 560.1 6.8 1.3 1.5 1.8 2.9 0.2 252.2 0.4 0.2 9.4 2.9 0.1 1.3 2.1 0.0 5.4 23.9 0.5 0.2 2.1 0.1 0.0 0.2 0.0 0.1 0.3 799.9 0.0 0.0 0.0 0.0 0.9 0.5 0.7 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 4.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 THAP4 "CGI-36, Nb(III)" ENSG00000176946 "THAP domain containing 4" Q8WY91 2 241584405-241637158 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "DNA-binding, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 223.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044982, HPA053448" Uncertain Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nuclear speckles" "HPA044982: AB_10959786, HPA053448: AB_2682154" "unprognostic (3.17e-2)" "unprognostic (1.70e-2)" "unprognostic (6.56e-2)" "unprognostic (1.36e-2)" "unprognostic (8.35e-2)" "unprognostic (7.23e-2)" "unprognostic (1.16e-3)" "unprognostic (3.61e-2)" "unprognostic (7.56e-2)" "unprognostic (2.18e-1)" "unprognostic (3.24e-1)" "unprognostic (2.21e-1)" "prognostic favorable (1.46e-4)" "unprognostic (2.57e-1)" "unprognostic (1.78e-1)" "unprognostic (5.06e-1)" "unprognostic (1.07e-1)" 34.3 31.8 60.3 19.0 60.4 28.1 35.6 57.7 78.5 34.5 60.2 51.1 42.1 30.9 28.7 53.1 29.0 25.0 106.5 58.9 60.7 96.7 54.0 29.3 22.0 60.0 61.4 33.2 48.4 107.0 37.7 16.1 60.3 43.7 27.1 9.0 42.1 24.1 118.8 46.8 34.9 17.3 56.3 26.5 52.0 40.8 62.7 23.4 31.9 91.6 19.0 41.5 38.9 59.8 47.6 53.4 31.5 58.9 41.5 43.1 53.7 32.1 42.5 46.6 41.4 48.6 41.1 40.5 16.4 50.1 53.8 53.4 63.8 71.4 17.6 33.3 76.9 42.5 35.7 138.7 55.0 48.6 28.5 44.8 55.4 50.2 69.2 32.5 43.9 62.4 76.9 13.1 36.4 84.5 51.1 110.1 57.1 43.9 45.2 55.9 44.1 52.6 100.2 57.0 76.4 50.1 24.7 76.9 65.1 19.4 38.7 52.3 40.0 55.5 36.6 50.7 58.3 32.4 19.9 42.6 40.2 40.4 40.9 31.0 15.7 40.3 27.4 18.0 29.4 21.6 30.3 25.5 16.4 25.0 28.6 23.3 10.2 22.7 24.1 23.2 53.6 16.1 60.3 60.4 57.7 78.5 58.9 60.7 60.0 61.4 60.3 56.3 62.7 59.8 16.6 19.2 21.7 15.7 16.4 20.0 42.1 31.9 21.1 9.9 21.2 17.1 55.9 35.8 28.3 40.5 4.2 23.4 13.2 64.6 223.0 48.0 17.7 37.5 19.6 17.7 28.8 21.5 12.2 27.8 24.6 19.9 35.2 58.9 7.0 16.6 13.6 38.0 17.7 8.4 12.8 52.3 32.6 11.4 10.6 7.7 18.0 14.2 12.4 7.5 15.3 11.1 22.6 11.1 11.5 27.6 44.2 19.5 21.3 38.1 79.0 90.0 21.3 6.8 32.9 16.3 23.3 25.3 29.1 40.0 25.9 27.5 15.1 17.5 60.2 53.4 THBS2 TSP2 ENSG00000186340 "Thrombospondin 2" P35442 6 169215780-169254050 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 86.8;Endometrial stromal cells: 71.1;Fibroblasts: 127.7;Langerhans cells: 69.8;Melanocytes: 56.9;Oligodendrocyte precursor cells: 40.7;Oligodendrocytes: 55.8;Smooth muscle cells: 33.7;Suprabasal keratinocytes: 42.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 250.2;ASC TERT1: 200.3;BJ hTERT+: 88.6;BJ hTERT+ SV40 Large T+: 96.3;BJ hTERT+ SV40 Large T+ RasG12V: 117.8;HSkMC: 113.2;hTEC/SVTERT24-B: 127.2;U-2197: 107.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017716, HPA044304" Approved Approved "Nuclear speckles,Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 21000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear speckles, Cytosol" "CAB017716: , HPA044304: AB_2678891" "unprognostic (2.85e-2)" "unprognostic (1.41e-1)" "unprognostic (5.87e-2)" "unprognostic (8.90e-2)" "unprognostic (3.64e-2)" "unprognostic (8.73e-2)" "unprognostic (2.93e-1)" "unprognostic (5.10e-3)" "unprognostic (1.39e-1)" "unprognostic (4.71e-2)" "unprognostic (4.00e-2)" "unprognostic (2.56e-1)" "prognostic unfavorable (3.77e-6)" "unprognostic (2.19e-3)" "unprognostic (4.38e-2)" "unprognostic (4.16e-2)" "unprognostic (2.48e-3)" 52.9 7.9 5.5 14.8 15.4 0.0 36.2 10.9 7.7 63.1 0.2 20.4 2.5 50.0 0.7 12.0 34.7 50.4 44.2 6.5 13.1 8.3 8.2 19.8 3.3 17.1 18.2 33.2 5.6 1.7 9.5 2.2 21.4 9.7 2.4 0.1 8.2 2.5 3.4 41.1 9.2 21.3 11.3 3.3 5.4 2.3 15.0 0.6 17.0 1.8 1.2 29.1 30.8 19.3 0.2 0.0 2.5 1.1 250.2 200.3 0.0 76.8 88.6 96.3 117.8 0.4 0.0 0.1 0.1 76.1 0.2 0.1 2.4 3.2 22.5 0.0 0.0 0.0 0.0 0.0 73.1 0.3 0.0 113.2 0.0 127.2 0.0 0.2 0.0 0.0 0.0 0.1 3.7 0.0 0.1 1.7 16.3 0.0 0.6 0.0 0.1 1.1 0.0 0.4 0.3 0.2 0.2 0.1 0.0 0.2 0.0 0.7 0.0 46.1 0.4 107.6 9.3 0.1 0.7 0.0 30.6 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 15.4 10.9 7.7 6.5 13.1 17.1 18.2 21.4 11.3 15.0 19.3 3.5 6.4 0.0 6.8 0.0 86.8 1.6 0.1 1.8 0.4 2.2 1.8 5.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.2 3.1 71.1 4.6 0.0 0.0 1.2 0.0 0.0 127.7 1.1 1.4 0.0 0.0 15.4 0.0 0.3 0.0 1.7 0.0 0.0 0.0 69.8 0.3 8.1 1.2 56.9 6.5 0.0 0.2 0.0 40.7 55.8 0.5 0.0 16.1 0.0 1.9 0.0 4.4 0.0 0.2 0.0 1.0 33.7 0.0 0.4 1.2 42.3 0.1 2.1 5.5 0.0 0.9 THEM6 "C8orf55, DSCD75" ENSG00000130193 "Thioesterase superfamily member 6" Q8WUY1 8 142727223-142736927 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 82.4;RT4: 114.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA023255 Uncertain Approved "Nuclear speckles,Cytosol" "Secreted - unknown location" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "Nuclear speckles, Cytosol" "HPA023255: AB_1845782" "unprognostic (6.20e-3)" "unprognostic (2.21e-1)" "unprognostic (9.10e-2)" "unprognostic (5.33e-2)" "unprognostic (3.44e-2)" "unprognostic (1.00e-2)" "unprognostic (1.74e-2)" "unprognostic (6.47e-2)" "unprognostic (2.76e-1)" "unprognostic (1.44e-1)" "unprognostic (4.91e-2)" "unprognostic (6.76e-2)" "prognostic favorable (6.66e-7)" "unprognostic (7.02e-3)" "unprognostic (3.55e-2)" "unprognostic (2.39e-2)" "prognostic favorable (4.49e-4)" 14.3 17.2 15.8 4.4 13.9 5.3 15.6 14.4 18.3 9.6 12.0 13.3 11.5 6.9 3.5 21.0 9.4 7.3 16.6 16.1 15.4 21.6 47.0 10.6 6.5 20.7 17.2 4.4 23.1 15.7 12.5 8.3 16.7 12.5 5.1 1.4 16.3 10.3 12.4 16.6 11.6 3.5 15.0 11.0 15.6 3.7 15.9 6.8 14.2 7.2 4.1 17.2 11.5 14.2 28.5 23.1 3.5 23.9 10.9 3.8 16.6 14.3 11.8 21.5 14.9 14.2 41.5 11.9 31.8 5.4 8.0 64.4 10.2 31.0 3.5 9.9 28.2 9.1 12.3 28.9 11.9 5.3 9.2 5.5 10.9 4.2 6.0 4.3 18.4 16.6 4.3 5.9 3.7 82.4 21.7 1.3 5.4 53.0 74.5 24.9 2.4 27.4 25.9 114.0 53.1 20.8 21.9 64.7 18.6 3.2 31.9 4.3 10.7 9.2 6.7 26.8 2.5 3.8 5.6 5.2 9.5 25.7 11.6 7.2 4.9 2.6 10.9 9.2 16.6 5.1 11.6 14.1 4.7 6.7 13.6 12.9 0.7 11.1 9.0 3.6 11.6 9.1 15.8 13.9 14.4 18.3 16.1 15.4 20.7 17.2 16.7 15.0 15.9 14.2 35.4 9.6 5.8 6.2 6.7 3.6 7.5 5.7 2.8 10.4 24.7 25.3 7.4 11.5 7.8 18.4 6.2 18.3 11.5 16.6 5.9 13.7 3.3 5.5 3.0 14.6 31.8 11.6 11.3 11.6 10.1 4.8 7.7 9.0 0.0 6.6 19.2 20.8 11.4 16.8 7.8 13.5 6.1 3.1 1.4 15.7 2.8 3.9 5.4 2.8 2.3 13.5 16.5 11.6 7.3 9.4 9.0 4.1 3.7 10.7 29.0 16.2 2.4 11.3 0.0 6.1 4.3 2.7 5.7 18.4 7.7 3.4 10.3 8.2 22.4 25.1 THOC1 "HPR1, P84" ENSG00000079134 "THO complex 1" Q96FV9 18 214520-268050 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, mRNA processing, mRNA splicing, mRNA transport, Transcription, Transcription regulation, Transport" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019096, HPA019687" Enhanced Enhanced "Nuclear speckles" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" "Nuclear speckles" "HPA019096: AB_1857979, HPA019687: AB_1857980" "prognostic favorable (8.43e-4)" "unprognostic (2.06e-3)" "unprognostic (1.84e-1)" "unprognostic (3.69e-2)" "unprognostic (8.75e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.83e-5)" "unprognostic (6.74e-3)" "unprognostic (2.49e-3)" "prognostic favorable (2.89e-5)" "unprognostic (3.60e-2)" "unprognostic (1.35e-2)" "prognostic unfavorable (1.80e-6)" "unprognostic (2.03e-1)" "unprognostic (2.24e-1)" "unprognostic (3.42e-1)" "prognostic favorable (9.62e-4)" 6.0 5.2 8.7 8.1 9.7 7.5 5.8 10.0 12.2 5.5 9.8 6.6 6.3 4.7 4.5 6.5 4.1 4.6 4.6 8.8 8.8 7.5 9.9 4.6 12.3 9.4 9.0 4.7 3.9 6.7 3.7 6.4 9.9 5.1 5.5 5.8 6.9 4.1 6.2 6.3 5.9 5.7 8.8 6.3 5.3 16.8 9.5 12.8 4.7 6.2 11.6 9.5 3.8 10.7 27.0 15.8 32.4 26.1 20.8 15.4 40.2 15.4 14.5 29.8 31.1 30.8 16.1 37.2 11.9 20.0 46.0 17.1 43.0 24.4 36.9 12.3 19.1 22.2 18.4 21.0 16.0 50.5 20.2 10.6 14.4 33.3 21.8 13.6 33.3 34.5 52.3 17.4 27.3 20.5 38.1 29.6 31.5 34.2 21.1 53.3 30.3 33.4 17.2 26.1 21.2 16.6 39.0 19.9 25.3 36.7 14.0 37.1 16.6 26.6 29.9 21.8 48.3 15.9 26.4 54.7 22.2 36.0 22.8 13.4 7.3 6.4 9.8 10.7 14.8 13.3 11.7 12.4 11.9 11.5 13.5 13.4 0.7 11.2 9.4 7.2 12.8 6.6 8.7 9.7 10.0 12.2 8.8 8.8 9.4 9.0 9.9 8.8 9.5 10.7 20.4 19.2 11.7 48.3 21.0 12.9 15.6 16.8 23.9 30.8 13.1 14.1 9.6 2.8 17.9 11.0 20.9 24.7 23.2 6.0 15.6 16.5 67.1 15.0 23.6 16.7 9.5 21.0 45.3 8.2 16.7 19.9 9.2 21.9 27.3 32.4 8.2 10.3 16.1 28.6 51.6 8.7 10.2 6.9 11.1 11.6 19.3 15.0 3.6 32.8 14.3 12.9 10.3 41.7 74.6 12.7 7.0 17.0 15.6 16.7 9.2 10.2 10.5 27.6 6.6 21.6 22.9 73.4 30.5 13.8 9.1 18.7 22.3 17.7 13.4 12.9 THOC6 "fSAP35, MGC2655, WDR58" ENSG00000131652 "THO complex 6" Q86W42 16 3024027-3027755 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, mRNA processing, mRNA splicing, mRNA transport, Transport" "Developmental protein, RNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 107.8;Extravillous trophoblasts: 121.1;Prostatic glandular cells: 109.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052953 Uncertain Supported "Nucleoplasm,Nuclear speckles" No No "Cluster 28: Myeloid DCs - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Nuclear speckles" "HPA052953: AB_2681997" "unprognostic (2.07e-2)" "unprognostic (4.13e-3)" "unprognostic (1.70e-1)" "unprognostic (2.04e-1)" "unprognostic (2.08e-1)" "unprognostic (2.91e-1)" "unprognostic (7.82e-3)" "unprognostic (1.81e-1)" "unprognostic (1.31e-1)" "unprognostic (2.20e-2)" "unprognostic (5.15e-2)" "unprognostic (3.44e-2)" "prognostic unfavorable (4.40e-4)" "unprognostic (3.59e-1)" "unprognostic (1.43e-1)" "unprognostic (6.17e-2)" "unprognostic (9.43e-2)" 17.0 16.9 8.6 16.1 9.1 23.5 15.3 9.6 11.2 16.1 9.7 17.9 18.8 20.3 6.0 19.3 13.9 10.5 15.8 8.6 9.2 22.2 21.3 17.5 20.8 11.6 9.1 11.6 12.9 10.8 17.4 18.2 11.8 21.1 10.1 2.1 15.2 12.2 25.9 24.9 19.2 12.5 9.2 22.7 15.6 10.4 10.2 19.6 15.7 8.4 16.1 17.1 16.5 9.5 37.3 59.6 42.0 45.0 21.1 23.9 74.4 11.3 25.7 25.7 37.8 39.6 42.8 70.0 36.0 18.9 19.1 49.9 46.3 35.6 14.0 62.3 59.9 38.0 58.6 58.7 35.9 56.2 80.0 24.3 42.6 31.4 76.9 32.4 24.1 39.7 56.1 36.5 12.8 87.0 32.0 103.3 76.2 21.4 25.3 84.7 31.6 82.4 27.1 18.6 86.4 41.0 31.8 49.9 21.7 18.1 35.9 60.0 20.1 26.8 61.1 30.6 41.3 26.3 24.3 85.5 7.0 38.1 27.3 2.4 61.3 13.6 35.2 62.2 36.2 37.8 32.6 34.7 88.6 43.2 37.1 39.1 4.4 38.8 35.7 74.3 38.0 45.4 8.6 9.1 9.6 11.2 8.6 9.2 11.6 9.1 11.8 9.2 10.2 9.5 11.0 19.2 7.4 1.6 24.7 68.2 84.9 59.0 30.7 3.7 22.1 20.8 3.3 14.3 18.9 18.4 2.1 107.8 23.3 23.2 35.2 33.1 5.4 17.9 19.0 17.9 25.8 30.3 1.9 23.5 121.1 24.6 15.3 25.8 12.0 15.6 6.4 10.3 51.8 3.3 1.7 32.3 44.7 19.4 37.3 3.2 14.9 23.4 24.9 2.8 39.6 3.2 15.5 0.5 4.2 21.5 28.0 12.0 19.7 109.4 32.1 32.0 8.7 2.4 6.6 23.4 31.9 5.3 23.3 23.3 44.9 77.2 20.4 20.9 42.2 46.8 THOC7 "FLJ23445, fSAP24, NIF3L1BP1" ENSG00000163634 "THO complex 7" Q6I9Y2 3 63833870-63863868 "Predicted intracellular proteins" "mRNA processing, mRNA splicing, mRNA transport, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 1032.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044143 Approved Supported "Nuclear speckles,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Nuclear speckles, Cytosol" "HPA044143: AB_10794892" "unprognostic (4.33e-2)" "unprognostic (9.68e-2)" "unprognostic (1.75e-2)" "unprognostic (1.30e-1)" "unprognostic (2.26e-2)" "unprognostic (2.86e-1)" "unprognostic (1.20e-3)" "unprognostic (3.53e-2)" "unprognostic (1.85e-2)" "unprognostic (1.52e-2)" "unprognostic (2.86e-2)" "unprognostic (9.90e-2)" "unprognostic (3.26e-2)" "unprognostic (1.51e-2)" "unprognostic (5.18e-2)" "unprognostic (4.25e-2)" "unprognostic (2.31e-1)" 54.7 63.5 57.1 43.2 60.0 80.1 75.1 58.1 85.1 54.4 52.0 69.9 64.2 50.5 53.2 73.1 43.0 48.6 88.0 61.5 59.1 67.8 73.5 40.9 68.1 58.4 59.1 44.4 62.3 52.1 33.5 53.5 57.1 43.8 69.1 64.5 50.5 49.5 103.5 64.2 53.7 59.6 57.3 38.2 49.1 47.6 57.8 72.3 44.4 104.0 68.0 60.8 50.3 61.1 141.2 83.5 95.6 23.9 125.1 172.5 89.6 120.2 126.9 139.2 140.1 101.6 151.5 168.3 49.1 155.1 139.2 79.3 107.5 190.4 194.1 169.6 75.5 150.2 102.8 117.2 130.1 212.6 69.6 123.9 157.2 118.4 213.1 137.6 155.1 110.0 116.8 158.6 170.2 1032.4 186.4 186.9 120.4 304.8 65.5 132.3 89.7 227.4 245.4 128.0 47.3 107.8 105.0 147.6 171.6 93.9 93.6 289.6 113.6 100.8 105.9 125.1 216.3 101.3 162.3 204.1 125.3 268.3 133.5 73.1 40.4 33.1 38.7 47.7 54.0 46.7 47.9 53.2 59.0 31.5 40.5 43.4 23.4 55.6 41.9 54.0 61.7 35.6 57.1 60.0 58.1 85.1 61.5 59.1 58.4 59.1 57.1 57.3 57.8 61.1 82.6 89.8 45.0 14.4 59.2 61.6 91.2 179.9 70.6 53.5 70.9 121.3 143.8 81.5 102.9 84.6 18.8 180.3 66.0 62.1 207.4 145.2 84.7 100.7 75.6 57.8 55.2 159.7 26.8 126.9 166.1 65.4 47.4 73.8 54.4 74.3 44.6 78.1 111.6 48.8 26.4 106.3 101.7 75.6 58.9 89.7 88.9 70.2 67.6 14.0 173.1 82.5 93.7 12.5 18.9 127.6 86.7 71.5 53.3 96.6 108.8 241.2 102.1 73.1 52.6 66.9 83.4 244.9 54.5 116.6 71.6 213.4 68.0 80.7 133.2 95.7 THRAP3 "BCLAF2, TRAP150" ENSG00000054118 "Thyroid hormone receptor associated protein 3" Q9Y2W1 1 36224432-36305357 "Plasma proteins, Predicted intracellular proteins" "Biological rhythms, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012041, CAB017472, HPA063765" Supported Enhanced "Nuclear speckles" NA NA 59000 "Cluster 6: Non-specific - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "CAB017472: AB_2271759, HPA012041: AB_1857983, HPA063765: AB_2685117" "unprognostic (8.53e-2)" "unprognostic (1.68e-1)" "unprognostic (9.29e-2)" "unprognostic (2.11e-1)" "unprognostic (1.71e-2)" "unprognostic (4.70e-2)" "unprognostic (2.65e-3)" "unprognostic (1.67e-1)" "unprognostic (9.30e-2)" "unprognostic (1.16e-1)" "unprognostic (5.08e-2)" "unprognostic (4.82e-2)" "unprognostic (3.34e-2)" "prognostic favorable (5.36e-4)" "unprognostic (7.56e-2)" "unprognostic (7.52e-2)" "unprognostic (1.23e-1)" 41.9 40.6 24.0 45.9 24.7 44.6 43.7 28.5 26.3 36.6 31.2 40.2 33.9 39.5 34.9 40.6 39.3 29.6 47.2 24.3 26.2 32.3 45.8 37.4 57.1 25.6 24.6 45.3 35.6 52.0 30.0 40.1 26.7 50.4 38.7 40.9 38.8 31.3 115.3 38.2 35.1 42.1 24.1 48.0 37.8 34.3 25.0 63.1 46.0 64.0 60.8 37.1 36.2 28.1 100.7 63.9 110.1 94.9 88.0 69.7 90.9 104.6 107.4 107.2 109.8 74.7 91.5 187.5 38.5 113.8 73.8 89.1 125.2 106.9 131.3 97.4 70.1 157.7 94.3 85.6 94.6 157.2 102.5 105.7 65.7 107.1 86.7 75.2 118.4 107.5 127.8 93.5 77.6 57.8 180.4 92.7 130.5 64.2 50.4 163.6 133.4 99.4 77.0 125.4 69.6 83.9 117.5 77.0 92.7 108.7 73.1 69.3 122.4 89.2 100.4 82.5 111.6 56.7 80.7 162.4 82.2 109.2 92.7 85.8 36.9 64.7 51.5 43.9 46.0 53.6 43.9 46.5 42.4 61.0 46.4 43.1 80.8 51.2 48.6 46.7 40.7 47.3 24.0 24.7 28.5 26.3 24.3 26.2 25.6 24.6 26.7 24.1 25.0 28.1 101.0 115.4 101.7 32.3 136.1 56.7 94.5 126.9 78.0 98.0 76.4 65.5 113.7 75.8 106.2 47.8 31.3 150.7 151.9 64.3 97.8 155.7 9.7 92.1 114.7 96.2 72.4 114.9 65.6 104.1 147.2 98.3 58.6 106.0 92.9 120.5 80.7 78.8 101.6 87.5 63.2 70.1 89.5 77.1 71.7 12.0 80.2 89.9 72.9 53.4 155.5 129.4 196.7 47.7 53.4 111.5 61.9 83.5 119.7 125.2 51.6 76.0 87.6 93.2 92.1 114.6 116.5 145.9 118.4 89.6 68.5 144.1 129.0 141.0 87.1 86.4 TLCD4 "FLJ31842, TMEM56" ENSG00000152078 "TLC domain containing 4" Q96MV1 1 95117355-95197607 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 130.0" "Cell type enriched" "Detected in some" 9 "Cardiomyocytes: 77.9" "Cancer enhanced" "Detected in many" "liver cancer: 13.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 22.4;RH-30: 35.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046762 Approved "Nuclear speckles" No No "Cluster 19: B-cells - Humoral immune response" "Cluster 85: Liver - Metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nuclear speckles" "HPA046762: AB_2679792" "unprognostic (1.51e-3)" "unprognostic (1.54e-1)" "unprognostic (2.98e-3)" "unprognostic (2.79e-1)" "unprognostic (3.30e-2)" "unprognostic (2.31e-1)" "unprognostic (3.82e-3)" "unprognostic (3.63e-2)" "unprognostic (4.42e-3)" "unprognostic (2.69e-2)" "unprognostic (4.99e-2)" "unprognostic (4.40e-2)" "unprognostic (1.16e-3)" "unprognostic (1.10e-1)" "unprognostic (9.46e-2)" "unprognostic (1.59e-1)" "unprognostic (3.15e-2)" 5.3 9.9 9.4 2.1 10.6 20.5 2.6 19.5 15.1 2.4 0.0 13.6 5.5 3.4 2.5 2.3 2.4 4.2 25.7 10.6 6.3 5.7 130.0 3.7 0.4 4.9 5.7 1.7 7.4 6.4 3.4 4.4 4.2 5.3 10.2 3.1 8.3 2.9 13.0 1.6 8.5 3.6 6.9 0.7 5.0 4.8 9.9 0.3 7.3 9.7 0.5 4.7 1.3 12.6 22.4 12.6 1.7 2.6 0.8 0.0 2.9 0.8 0.5 2.8 6.5 9.1 10.4 0.0 10.7 0.4 20.0 0.2 7.4 1.1 4.8 15.5 4.1 0.5 9.2 2.0 0.8 0.4 0.6 1.2 0.4 2.1 0.0 4.4 0.0 1.2 19.8 1.2 0.6 1.9 1.3 0.1 1.7 0.7 6.9 0.0 35.7 0.6 12.0 14.4 4.5 3.6 15.6 10.8 6.7 1.8 11.7 0.4 0.2 0.3 9.0 1.1 7.9 3.8 8.0 0.0 1.5 0.1 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 9.4 10.6 19.5 15.1 10.6 6.3 4.9 5.7 4.2 6.9 9.9 12.6 5.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 77.9 0.0 0.0 0.0 0.0 8.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.5 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 TMEM179B ENSG00000185475 "Transmembrane protein 179B" Q7Z7N9 11 62787402-62790400 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016585, HPA062068" Enhanced "Nuclear speckles" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nuclear speckles" "HPA016585: AB_1844357, HPA062068: AB_2684676" "unprognostic (1.18e-2)" "unprognostic (2.83e-1)" "unprognostic (2.20e-1)" "unprognostic (1.78e-2)" "unprognostic (1.68e-1)" "unprognostic (6.11e-3)" "unprognostic (1.96e-2)" "unprognostic (2.35e-1)" "unprognostic (2.44e-1)" "unprognostic (1.25e-2)" "unprognostic (4.61e-3)" "unprognostic (2.76e-2)" "unprognostic (4.56e-1)" "unprognostic (1.64e-1)" "unprognostic (2.16e-1)" "unprognostic (5.74e-3)" "unprognostic (3.60e-2)" 52.1 60.3 32.4 22.0 34.7 21.5 55.0 33.7 36.4 50.5 41.8 48.7 34.7 44.4 71.2 47.9 46.7 28.4 34.0 30.8 32.9 54.3 64.3 51.0 26.9 35.3 33.3 39.6 58.7 34.1 31.0 30.0 35.6 45.8 40.1 10.4 59.1 26.4 27.2 58.2 49.8 26.3 33.7 48.1 53.9 41.6 33.0 33.0 55.4 21.6 29.8 43.3 46.0 36.9 35.6 68.8 17.7 35.7 136.3 34.3 22.6 38.2 47.5 29.8 34.2 39.3 82.9 16.5 53.1 78.0 44.2 64.8 33.4 35.4 23.2 48.6 44.9 24.1 29.2 36.3 90.8 30.9 32.2 65.8 55.8 57.1 70.0 60.0 30.3 46.9 33.2 46.3 34.5 81.1 40.2 59.5 26.5 76.8 74.6 26.5 28.8 86.1 57.7 42.6 24.4 26.7 49.3 65.3 70.4 35.8 76.2 37.8 42.2 39.6 29.4 73.3 32.2 51.2 32.5 22.6 57.0 19.0 47.3 302.9 300.4 332.7 149.4 305.0 147.9 169.2 135.5 144.9 198.2 140.6 118.2 117.3 224.3 140.2 305.9 366.1 146.6 282.5 32.4 34.7 33.7 36.4 30.8 32.9 35.3 33.3 35.6 33.7 33.0 36.9 119.6 60.9 59.2 15.3 52.7 68.7 73.9 175.6 86.0 12.4 108.0 122.2 1.3 65.8 121.1 60.7 0.0 174.5 71.7 91.2 37.2 138.1 5.8 75.2 54.5 83.7 65.2 40.4 9.9 149.0 160.5 76.8 54.6 66.5 54.6 43.8 69.9 81.9 133.2 8.4 9.0 103.5 128.1 63.7 83.0 11.0 75.8 76.5 106.7 12.2 98.3 74.4 91.6 16.1 28.1 124.0 137.1 45.9 93.9 97.1 179.4 87.5 122.9 14.7 65.7 50.5 57.8 120.8 100.5 93.2 76.0 185.1 60.0 90.4 94.8 97.5 TMEM209 "FLJ14803, NET31" ENSG00000146842 "Transmembrane protein 209" Q96SK2 7 130164713-130207770 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031678 Uncertain Approved "Nuclear membrane,Nuclear speckles,Vesicles" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nuclear membrane, Nuclear speckles, Vesicles" "HPA031678: AB_10603135" "unprognostic (3.03e-1)" "unprognostic (5.06e-2)" "unprognostic (1.55e-1)" "unprognostic (9.54e-2)" "unprognostic (1.85e-1)" "unprognostic (1.36e-1)" "unprognostic (4.50e-3)" "unprognostic (5.98e-2)" "unprognostic (1.25e-1)" "unprognostic (1.66e-1)" "unprognostic (3.19e-1)" "unprognostic (6.00e-2)" "unprognostic (2.34e-3)" "unprognostic (1.11e-1)" "unprognostic (3.48e-1)" "unprognostic (1.68e-2)" "unprognostic (3.24e-1)" 8.9 15.3 4.1 8.4 6.2 9.6 10.6 7.2 6.5 7.4 13.0 11.0 8.8 10.8 9.5 5.5 9.6 6.4 6.2 4.0 5.2 8.6 10.4 9.2 11.9 6.1 6.1 10.2 8.5 15.1 4.4 9.5 6.4 8.3 11.2 13.3 7.9 8.4 5.2 7.2 10.7 9.0 5.9 10.5 7.6 15.0 5.4 14.2 16.2 7.7 12.1 7.6 4.3 9.6 23.4 21.8 29.3 36.7 16.8 17.2 21.4 20.8 20.9 18.3 24.7 23.0 39.2 34.6 15.1 13.3 34.5 34.2 34.7 24.2 33.0 42.7 20.0 17.9 34.0 16.5 29.6 38.2 17.2 18.9 24.6 37.0 36.8 11.4 14.5 35.1 58.9 38.2 23.2 30.2 73.2 23.6 44.1 20.9 19.4 38.9 33.1 57.4 19.1 29.3 26.2 40.0 47.5 75.8 31.3 22.7 23.7 25.6 11.4 33.0 13.1 35.4 50.6 51.7 81.6 70.4 54.7 43.4 53.0 16.1 12.2 13.8 22.0 18.3 23.0 18.3 22.3 20.2 12.0 17.3 25.6 22.3 1.8 19.5 16.8 14.9 24.6 15.1 4.1 6.2 7.2 6.5 4.0 5.2 6.1 6.1 6.4 5.9 5.4 9.6 12.3 3.2 12.3 11.4 15.3 4.7 4.0 8.2 6.8 13.6 8.8 5.2 8.6 10.0 9.8 9.2 4.2 8.9 15.2 7.2 1.9 6.4 33.5 9.6 8.0 9.5 13.8 25.9 10.4 9.1 9.3 7.5 7.7 10.4 10.1 10.0 9.7 9.4 7.9 5.0 13.0 11.9 8.2 13.1 4.4 8.5 6.5 7.8 7.2 15.0 7.7 18.1 8.2 10.6 20.9 7.6 11.6 5.3 11.0 5.3 13.4 4.9 9.8 14.6 0.0 9.0 5.9 16.6 16.0 6.4 5.4 6.6 13.1 12.1 9.5 3.7 TMEM259 "ASBABP1, C19orf6, MBRL, MGC4022" ENSG00000182087 "Transmembrane protein 259" Q4ZIN3 19 1009648-1021179 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042669, HPA054801" Approved Approved "Nuclear speckles,Endoplasmic reticulum" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 18: Non-specific - Mitochondria" "Cluster 29: U-266 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" "Endoplasmic reticulum" "Nuclear speckles" "HPA042669: AB_10794916, HPA054801: AB_2682604" "unprognostic (1.35e-1)" "unprognostic (1.28e-1)" "unprognostic (1.41e-1)" "prognostic favorable (1.01e-4)" "unprognostic (4.12e-2)" "unprognostic (6.87e-3)" "unprognostic (2.77e-2)" "unprognostic (1.23e-1)" "unprognostic (2.20e-1)" "unprognostic (2.74e-1)" "unprognostic (4.85e-3)" "unprognostic (4.07e-2)" "unprognostic (4.81e-2)" "prognostic favorable (8.92e-6)" "unprognostic (2.47e-1)" "unprognostic (2.57e-1)" "unprognostic (4.10e-3)" 114.9 119.8 59.6 68.7 62.3 82.4 112.4 59.9 74.5 111.8 71.3 117.4 66.8 108.0 22.3 114.7 110.9 48.0 129.9 57.0 61.3 119.3 162.6 128.5 75.2 72.1 65.6 106.5 127.3 83.2 154.2 50.3 63.7 126.3 33.9 39.1 109.2 45.6 112.7 128.6 135.7 35.2 58.9 191.5 115.5 101.2 66.1 71.9 133.2 48.2 47.8 103.3 113.1 75.5 125.0 78.3 53.6 61.3 64.7 62.2 94.4 101.1 89.5 83.7 89.9 73.2 68.6 84.8 98.5 78.9 39.4 138.9 54.4 102.0 36.9 108.5 88.0 50.4 102.9 81.2 114.6 98.1 122.5 83.7 102.2 67.5 83.6 79.5 73.7 85.6 85.5 168.2 56.8 54.9 106.5 89.9 78.3 63.1 60.2 120.8 40.6 110.1 66.3 115.1 73.7 77.8 64.9 82.2 73.9 43.0 80.9 125.3 87.0 83.0 47.2 118.5 108.2 240.2 95.7 96.2 98.3 79.3 84.6 0.6 1.7 1.0 2.2 1.4 1.6 1.6 1.3 2.2 2.5 1.3 1.3 1.6 1.1 1.2 2.3 2.9 1.4 1.6 59.6 62.3 59.9 74.5 57.0 61.3 72.1 65.6 63.7 58.9 66.1 75.5 73.6 32.1 49.9 64.6 70.1 62.3 54.5 26.0 51.2 118.5 50.3 44.7 14.1 30.0 27.6 66.2 98.0 59.2 90.0 114.1 11.7 28.4 18.3 46.5 56.4 50.4 40.2 21.0 36.3 34.3 51.4 49.6 122.3 63.5 15.2 89.4 40.7 52.0 51.1 104.3 40.8 78.4 18.3 30.0 58.1 11.4 42.6 55.2 44.4 36.5 28.7 65.9 26.8 35.2 58.4 42.9 75.8 34.3 89.1 63.7 56.2 20.7 26.3 170.2 32.9 48.5 51.2 45.4 38.5 53.8 64.9 82.4 69.3 126.4 62.6 66.3 TOR1B "DQ1, MGC4386" ENSG00000136816 "Torsin family 1 member B" O14657 9 129803157-129811281 "Predicted intracellular proteins" "Chaperone, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013403, HPA013697, CAB022709" Approved Uncertain "Nuclear speckles,Cytosol" "Intracellular and membrane" NA NA 140000 "Cluster 5: Granulocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nuclear speckles" Cytosol "CAB022709: , HPA013403: AB_1858195, HPA013697: AB_1858196" "unprognostic (2.91e-3)" "unprognostic (1.73e-1)" "unprognostic (1.14e-1)" "unprognostic (8.55e-2)" "unprognostic (3.23e-1)" "unprognostic (3.72e-2)" "unprognostic (1.75e-1)" "unprognostic (5.73e-3)" "unprognostic (1.95e-1)" "unprognostic (7.47e-2)" "unprognostic (1.40e-1)" "unprognostic (2.13e-2)" "unprognostic (2.07e-3)" "unprognostic (4.09e-2)" "unprognostic (1.23e-1)" "unprognostic (5.40e-3)" "unprognostic (1.69e-3)" 11.1 10.0 8.6 13.1 8.4 14.3 8.7 12.0 8.7 8.4 9.5 20.3 11.3 9.1 7.0 10.3 7.7 13.3 8.9 8.2 9.2 8.6 18.5 11.7 11.0 8.8 8.6 7.5 12.6 11.7 7.3 14.2 8.7 11.0 22.6 5.9 10.3 9.2 10.6 11.8 14.1 12.6 8.6 9.3 11.9 10.2 9.5 10.7 10.7 9.9 9.4 15.8 8.5 8.4 11.7 26.5 10.9 29.0 53.2 39.4 25.0 40.8 26.7 27.6 27.2 22.0 26.1 8.3 25.2 40.7 43.0 46.4 11.9 16.9 28.2 30.4 12.3 7.2 21.5 15.8 22.8 13.8 31.1 22.6 29.3 39.6 19.4 20.4 24.9 21.5 25.6 18.8 26.2 32.9 19.2 21.8 22.9 54.8 20.1 7.8 18.9 25.3 21.3 12.1 15.0 17.2 26.0 30.4 16.6 19.5 43.7 13.5 22.7 51.9 24.5 62.4 35.7 13.6 53.9 7.0 28.6 17.9 36.0 8.7 13.3 20.2 12.6 16.0 13.0 4.0 10.0 11.2 6.9 4.7 7.3 7.3 16.4 8.8 10.1 4.2 10.5 9.9 8.6 8.4 12.0 8.7 8.2 9.2 8.8 8.6 8.7 8.6 9.5 8.4 9.5 9.6 2.4 6.5 11.7 6.5 5.9 7.3 12.5 2.7 6.9 5.6 5.5 5.7 6.1 5.5 4.2 10.8 16.1 15.3 0.0 9.7 13.3 5.0 6.7 8.2 19.2 3.4 13.9 13.7 17.7 10.5 17.9 5.7 4.5 4.0 9.7 13.3 12.0 6.7 15.6 16.2 4.1 5.4 5.0 15.1 4.4 12.1 3.6 4.7 12.3 4.7 16.5 14.6 10.5 12.6 6.7 5.7 14.5 10.1 10.7 3.7 9.4 2.7 19.7 6.8 13.0 22.7 5.4 10.4 5.4 15.2 12.2 4.6 10.5 11.2 TREML1 "dJ238O23.3, TLT1" ENSG00000161911 "Triggering receptor expressed on myeloid cells like 1" Q86YW5 6 41149342-41154337 "Plasma proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 8.7;brain: 4.5;lymphoid tissue: 7.3" "Group enriched" "Detected in some" 7 "Macrophages: 75.6;monocytes: 28.3" "Cancer enhanced" "Detected in some" "glioma: 1.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "basophil: 92.4" "Lineage enriched" "Detected in many" 49 "granulocytes: 92.4" "Cell line enriched" "Detected in single" 170 "HEL: 66.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA016700, HPA017860" Enhanced Uncertain "Nuclear speckles,Golgi apparatus,Plasma membrane,Cytosol" NA NA 43000000 "Cluster 34: Basophils - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" "Nuclear speckles, Cytosol" "Golgi apparatus, Plasma membrane" "HPA016700: AB_1858262, HPA017860: AB_1858261" "unprognostic (6.70e-2)" "unprognostic (3.50e-3)" "unprognostic (1.15e-3)" "unprognostic (1.62e-1)" "unprognostic (3.48e-2)" "unprognostic (4.53e-5)" "unprognostic (1.10e-2)" "unprognostic (2.55e-3)" "unprognostic (4.50e-1)" "unprognostic (2.12e-3)" "unprognostic (2.34e-2)" "unprognostic (7.04e-2)" "unprognostic (1.11e-4)" "unprognostic (1.36e-1)" "unprognostic (8.38e-2)" "unprognostic (7.51e-2)" "unprognostic (3.41e-2)" 0.9 1.0 1.7 2.7 2.1 8.7 0.5 2.2 4.5 0.3 1.3 0.3 0.0 0.1 0.4 0.1 0.4 0.9 0.3 1.9 2.5 0.2 0.3 2.1 5.4 3.3 2.4 0.1 0.4 0.2 0.4 0.5 2.8 0.2 0.9 0.2 0.4 0.3 0.1 0.3 0.4 0.2 2.5 7.3 0.2 0.1 3.6 4.1 0.3 0.5 4.8 0.4 0.1 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 66.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 92.4 1.7 2.8 0.2 1.8 0.4 0.2 0.1 0.0 0.7 0.3 0.5 0.0 10.7 0.0 0.3 0.9 0.0 110.6 1.7 2.1 2.2 4.5 1.9 2.5 3.3 2.4 2.8 2.5 3.6 3.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.8 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 3.9 0.0 3.9 0.0 0.0 0.0 0.0 1.6 2.7 0.0 0.0 75.6 0.0 6.5 28.3 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 TRIP12 "KIAA0045, TRIPC, ULF" ENSG00000153827 "Thyroid hormone receptor interactor 12" Q14669 2 229763837-229923239 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Autism spectrum disorder, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 251.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036835, HPA045893" Enhanced Approved "Nuclear speckles" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" "Nuclear speckles" "HPA036835: AB_2675340, HPA045893: AB_2679486" "unprognostic (1.22e-1)" "unprognostic (4.87e-2)" "unprognostic (2.61e-1)" "unprognostic (3.33e-2)" "unprognostic (6.81e-2)" "unprognostic (1.88e-1)" "prognostic unfavorable (3.60e-4)" "unprognostic (3.37e-3)" "unprognostic (3.49e-3)" "unprognostic (4.87e-2)" "unprognostic (5.21e-2)" "unprognostic (1.11e-1)" "unprognostic (1.22e-1)" "unprognostic (1.62e-1)" "unprognostic (6.83e-2)" "unprognostic (8.80e-2)" "unprognostic (2.01e-2)" 48.2 32.3 20.2 47.1 26.7 53.9 33.6 20.2 31.4 34.8 15.7 40.8 25.6 30.8 33.4 47.6 28.1 33.9 41.5 16.0 25.4 41.3 42.8 33.3 48.2 20.7 20.8 32.7 29.3 45.0 24.8 44.6 22.1 39.9 33.9 34.8 30.2 33.0 81.7 29.3 27.6 38.2 17.9 41.1 39.1 127.7 21.5 60.3 44.5 59.0 56.3 46.3 26.5 30.0 97.1 100.7 96.2 79.0 94.9 106.2 88.3 144.5 103.0 106.9 118.7 80.5 75.3 37.8 96.2 135.6 129.5 76.3 140.5 105.9 159.3 132.4 52.9 264.1 84.4 78.3 76.4 195.8 163.2 88.1 80.3 174.9 108.5 74.9 145.1 88.2 188.2 38.2 122.5 72.5 105.3 68.5 77.0 50.3 47.7 94.8 189.8 33.6 75.7 156.4 94.4 67.5 1.6 51.9 97.7 85.1 48.2 118.3 188.8 133.9 94.7 84.9 115.5 66.4 79.3 119.0 103.8 77.0 116.6 34.0 14.2 23.6 12.9 16.2 13.1 9.6 12.0 12.7 13.4 8.9 9.5 9.7 36.0 13.9 18.7 12.6 19.5 9.8 20.2 26.7 20.2 31.4 16.0 25.4 20.7 20.8 22.1 17.9 21.5 30.0 78.3 89.8 51.2 85.8 43.4 31.0 32.8 36.3 25.6 31.2 41.2 29.8 91.0 34.3 52.8 31.3 52.1 27.0 60.8 57.3 15.6 37.5 119.5 63.5 65.2 59.3 18.6 40.2 147.6 45.1 25.1 43.7 56.6 73.5 39.2 53.1 50.0 54.3 35.1 42.1 130.3 32.5 30.5 89.6 32.2 102.1 34.8 70.8 26.6 122.7 63.9 25.8 56.7 127.2 251.3 57.8 35.0 45.5 52.1 44.7 25.7 34.5 73.1 32.1 19.7 57.5 45.0 137.2 59.3 43.1 36.2 42.4 47.0 60.2 31.9 54.5 TSC22D3 "DIP, DSIPI, GILZ, hDIP, TSC-22R" ENSG00000157514 "TSC22 domain family member 3" Q99576 X 107713221-107777342 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 1234.8;dendritic cells: 1146.4;Plasma cells: 2348.5;T-cells: 1479.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 380.5;ASC TERT1: 259.7;HHSteC: 628.0;hTCEpi: 572.7;Karpas-707: 364.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001916, CAB034364" Approved Approved "Nuclear speckles,Golgi apparatus,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" Cytosol "Nuclear speckles, Golgi apparatus" "CAB034364: AB_2272198, HPA001916: AB_2666504" "unprognostic (3.67e-2)" "unprognostic (3.90e-3)" "unprognostic (5.99e-2)" "prognostic unfavorable (2.43e-4)" "unprognostic (3.49e-2)" "unprognostic (3.21e-2)" "unprognostic (3.73e-3)" "unprognostic (4.40e-2)" "unprognostic (9.42e-2)" "unprognostic (5.32e-2)" "unprognostic (3.25e-1)" "unprognostic (7.47e-2)" "unprognostic (6.38e-2)" "unprognostic (1.37e-3)" "unprognostic (6.41e-2)" "unprognostic (4.14e-1)" "unprognostic (9.64e-2)" 536.4 240.5 90.3 394.8 93.5 433.3 447.3 101.0 105.0 396.4 104.1 290.2 87.2 269.3 72.0 300.4 369.8 167.1 331.9 81.3 102.9 194.9 177.4 522.6 281.0 99.6 97.2 371.1 113.8 55.7 136.2 163.8 98.9 404.4 183.6 22.5 333.4 160.5 729.3 493.6 426.3 178.7 92.8 408.2 390.4 43.8 99.3 203.2 313.0 187.8 338.2 508.2 486.9 91.3 10.9 18.2 9.3 25.7 380.5 259.7 3.7 16.9 14.1 7.8 8.6 0.1 35.8 23.4 40.1 13.7 5.5 53.5 19.1 54.2 3.3 7.0 9.0 11.5 76.9 1.0 628.0 2.5 37.7 238.8 572.7 6.1 158.7 78.8 29.3 2.5 3.6 364.1 67.2 37.8 0.7 40.5 16.3 11.5 11.7 1.2 23.5 51.3 26.1 7.3 2.4 20.3 16.6 89.2 128.8 16.9 17.0 52.4 44.1 23.6 7.1 4.8 3.4 79.6 37.8 11.2 12.0 46.7 6.7 668.9 417.2 1653.1 649.7 524.1 484.2 584.0 740.6 641.5 399.5 559.6 686.3 643.0 2396.6 968.4 851.8 81.4 1080.9 1624.1 90.3 93.5 101.0 105.0 81.3 102.9 99.6 97.2 98.9 92.8 99.3 91.3 423.5 64.1 164.7 10.4 1234.8 110.0 82.8 129.7 435.4 52.0 97.0 47.5 31.8 70.1 106.9 47.8 0.0 3.2 1146.4 26.2 232.8 28.3 28.8 24.2 40.9 171.7 64.2 481.5 13.1 22.2 140.5 454.2 200.3 29.7 353.2 15.3 247.0 95.6 121.3 62.2 12.9 32.9 83.4 396.3 191.8 41.2 230.5 539.1 437.6 16.9 126.0 8.9 234.8 37.7 23.7 22.7 19.6 319.7 2348.5 106.5 58.6 48.6 61.0 19.1 433.9 245.4 248.3 24.1 15.3 182.6 79.1 9.9 1479.6 89.6 33.0 42.2 U2AF2 U2AF65 ENSG00000063244 "U2 small nuclear RNA auxiliary factor 2" P26368 19 55654146-55674716 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010910, HPA041943, HPA043562" Supported Supported Enhanced "Nucleoplasm,Nuclear speckles" NA NA 73000 "Cluster 1: Neutrophils - Mixed function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nuclear speckles" Nucleoplasm "CAB010910: AB_262122, HPA041943: AB_2677760, HPA043562: AB_2678555" "unprognostic (2.37e-1)" "unprognostic (2.22e-1)" "unprognostic (3.12e-1)" "unprognostic (9.60e-2)" "unprognostic (6.94e-2)" "unprognostic (4.01e-2)" "prognostic unfavorable (1.54e-6)" "unprognostic (9.46e-2)" "unprognostic (1.36e-2)" "unprognostic (8.00e-2)" "unprognostic (3.33e-2)" "unprognostic (4.25e-3)" "unprognostic (2.19e-2)" "unprognostic (4.80e-2)" "unprognostic (9.88e-2)" "unprognostic (1.14e-1)" "unprognostic (3.08e-2)" 74.2 80.9 70.3 101.9 73.0 147.7 70.2 74.6 82.4 92.1 75.4 83.7 85.1 87.4 56.7 98.2 82.8 54.0 69.3 70.3 70.8 79.4 80.2 74.2 119.3 76.2 71.5 98.3 75.0 70.1 93.7 63.6 73.0 74.9 54.0 46.0 72.0 65.9 67.3 80.0 92.3 62.1 72.0 115.7 75.4 81.8 72.1 132.5 78.9 45.9 93.7 78.2 80.7 82.4 244.5 394.0 235.9 191.1 108.3 109.8 249.3 191.9 174.1 314.2 305.3 231.3 222.3 284.5 149.5 164.9 160.5 193.0 299.3 268.3 149.1 218.0 501.9 245.2 176.1 221.5 176.7 287.4 263.5 148.8 161.0 239.5 166.8 120.0 190.8 195.9 293.1 181.3 169.9 239.2 388.0 261.1 260.4 217.1 307.2 414.5 149.7 233.0 189.7 290.0 270.6 211.0 208.6 197.1 125.7 134.6 190.5 296.9 161.5 279.7 203.7 130.0 415.9 165.0 239.3 344.5 124.3 279.5 245.2 0.1 1.1 0.8 1.3 1.5 1.0 0.8 1.1 0.9 1.0 1.1 0.8 0.8 2.1 0.6 1.2 1.8 1.1 0.9 70.3 73.0 74.6 82.4 70.3 70.8 76.2 71.5 73.0 72.0 72.1 82.4 31.0 3.2 9.1 10.4 46.0 45.4 41.4 34.8 57.5 41.8 29.7 21.3 2.7 24.3 20.6 27.6 31.3 58.5 34.1 44.0 19.6 33.0 6.4 33.8 36.0 31.4 45.5 32.6 6.8 23.8 63.0 29.4 51.0 40.9 34.3 30.4 27.5 26.8 37.6 35.3 7.6 42.4 30.5 22.0 32.3 8.4 44.4 31.6 19.6 11.2 37.4 25.3 30.9 4.0 12.0 31.8 29.3 34.3 62.4 41.9 31.9 21.3 15.3 52.0 0.0 26.1 46.6 22.5 32.0 53.5 39.2 71.8 42.7 30.8 43.6 44.9 UBAP2L "KIAA0144, NICE-4" ENSG00000143569 "Ubiquitin associated protein 2 like" Q14157 1 154220179-154271510 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 147.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035068 Approved Approved "Nuclear speckles,Cytosol" NA NA 67000 "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles, Cytosol" "HPA035068: AB_10696366" "unprognostic (3.14e-2)" "unprognostic (1.50e-1)" "unprognostic (8.82e-2)" "unprognostic (2.93e-3)" "unprognostic (3.98e-2)" "unprognostic (2.19e-1)" "prognostic unfavorable (4.65e-5)" "unprognostic (1.97e-2)" "unprognostic (5.10e-3)" "unprognostic (9.01e-2)" "unprognostic (1.67e-1)" "unprognostic (6.96e-2)" "prognostic unfavorable (2.89e-5)" "unprognostic (7.40e-3)" "unprognostic (9.14e-2)" "unprognostic (2.69e-1)" "unprognostic (3.72e-1)" 54.1 49.3 30.7 60.9 31.3 62.8 50.0 29.2 40.4 52.2 32.5 53.2 34.2 59.8 48.6 55.0 54.6 44.8 62.7 32.0 31.2 39.8 36.6 54.5 60.7 26.3 27.6 60.5 37.9 60.4 49.4 70.6 26.3 45.7 40.8 46.0 48.0 47.1 83.1 60.2 40.6 55.2 20.4 53.6 45.9 64.5 27.2 59.5 53.6 49.1 65.9 54.0 50.9 35.0 189.3 184.8 167.4 136.5 121.0 138.0 148.1 212.1 154.9 187.6 131.6 197.9 143.6 235.3 213.2 178.9 94.6 160.8 224.3 158.4 167.7 208.1 199.7 255.7 184.6 162.7 113.7 269.6 144.0 130.5 68.3 173.8 114.8 117.9 153.1 92.0 235.0 111.5 152.6 212.6 207.8 101.1 320.4 140.1 170.9 148.9 135.5 207.8 120.7 220.5 173.1 209.3 245.1 227.2 91.4 186.8 226.6 180.6 245.9 117.0 123.8 145.1 205.7 239.1 278.4 313.2 125.7 144.8 179.0 15.1 28.2 20.4 23.1 35.9 25.4 20.9 21.8 21.2 34.9 26.4 24.6 27.7 24.5 36.4 41.3 16.3 21.5 29.6 30.7 31.3 29.2 40.4 32.0 31.2 26.3 27.6 26.3 20.4 27.2 35.0 29.2 25.6 38.5 22.9 31.7 18.4 18.7 21.5 22.2 18.4 21.5 21.5 39.0 17.2 32.3 18.4 8.4 51.3 32.7 16.7 17.6 28.4 80.6 34.3 43.8 26.8 23.4 34.9 26.7 27.1 39.5 29.0 21.9 35.7 24.7 32.3 23.2 19.1 36.1 15.2 25.3 21.7 26.4 22.6 30.2 147.1 21.5 32.4 19.6 26.2 24.5 13.7 24.7 29.1 29.1 30.9 10.4 22.6 20.6 25.1 12.5 15.9 29.7 20.4 13.1 31.1 51.6 42.2 48.8 31.7 20.5 77.8 23.5 35.6 22.0 21.9 UBE3B ENSG00000151148 "Ubiquitin protein ligase E3B" Q7Z3V4 12 109477402-109536705 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041012 Approved Approved "Nuclear speckles,Mitochondria" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 51: Myeloid cells - Hemostasis" "Nuclear speckles" Mitochondria "HPA041012: AB_10964435" "unprognostic (1.53e-2)" "unprognostic (1.01e-1)" "unprognostic (7.12e-2)" "unprognostic (7.37e-2)" "unprognostic (7.43e-2)" "unprognostic (1.29e-1)" "unprognostic (4.92e-2)" "unprognostic (7.19e-2)" "unprognostic (2.93e-1)" "unprognostic (4.46e-3)" "unprognostic (9.39e-2)" "unprognostic (1.23e-1)" "prognostic favorable (2.49e-5)" "unprognostic (3.35e-1)" "unprognostic (3.35e-2)" "unprognostic (2.87e-1)" "unprognostic (1.26e-1)" 13.8 16.5 14.4 10.7 16.1 9.2 13.7 13.3 15.6 14.4 16.5 17.8 12.9 14.1 13.4 18.6 16.2 12.1 26.2 14.4 12.4 16.7 16.0 13.6 12.6 13.7 14.6 15.8 14.3 22.6 13.6 13.1 14.8 15.4 18.1 14.9 14.4 14.1 34.0 19.2 15.8 14.7 12.5 15.8 16.5 12.9 16.1 12.6 18.2 29.7 13.5 17.0 14.5 20.3 17.1 26.4 20.4 14.8 33.9 27.1 17.9 22.1 25.1 26.2 17.4 28.0 17.1 10.6 16.0 36.3 22.5 21.5 20.9 28.3 25.1 23.4 14.7 20.3 17.6 25.5 21.7 16.7 16.2 31.0 25.8 25.4 30.2 39.5 28.7 24.8 22.7 9.7 30.2 26.6 11.5 24.2 21.0 19.1 31.6 18.8 19.2 20.9 22.4 30.2 19.1 34.9 25.8 34.6 17.3 23.7 35.3 17.6 26.5 32.3 9.2 16.8 16.0 21.8 19.4 18.6 32.1 13.7 27.4 22.9 12.9 12.8 12.6 14.5 12.4 13.6 12.1 9.0 12.4 10.0 10.0 13.3 16.1 13.1 12.0 11.4 16.2 10.7 14.4 16.1 13.3 15.6 14.4 12.4 13.7 14.6 14.8 12.5 16.1 20.3 11.9 12.8 15.1 34.0 9.7 5.1 11.8 13.9 6.8 19.3 14.4 12.8 35.4 11.5 17.1 16.5 33.3 17.9 12.8 21.0 11.7 17.7 15.7 12.6 12.5 14.2 9.0 13.0 24.5 15.3 11.5 11.1 18.8 12.2 9.5 20.0 11.7 18.8 12.5 21.9 23.6 15.9 18.3 19.2 6.1 32.0 12.5 14.2 10.6 13.1 17.7 13.6 32.0 21.1 38.3 25.3 13.7 9.8 15.6 17.2 19.6 19.9 18.4 25.0 6.6 9.4 13.0 10.4 13.2 13.4 7.2 23.7 10.7 17.7 16.8 18.4 UBE4A "E4, KIAA0126, UBOX2, UFD2" ENSG00000110344 "Ubiquitination factor E4A" Q14139 11 118359600-118399211 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA055035, HPA064010" Approved Supported "Nuclear speckles" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 59: Non-specific - Transcription" "Nuclear speckles" "HPA055035: AB_2682679, HPA064010: AB_2685174" "unprognostic (1.32e-2)" "unprognostic (8.15e-2)" "unprognostic (5.23e-3)" "unprognostic (3.34e-1)" "unprognostic (2.80e-2)" "unprognostic (1.97e-1)" "unprognostic (7.67e-3)" "unprognostic (3.31e-1)" "unprognostic (1.30e-1)" "unprognostic (4.67e-2)" "unprognostic (6.01e-2)" "unprognostic (5.83e-2)" "unprognostic (7.73e-3)" "unprognostic (4.74e-2)" "unprognostic (5.94e-2)" "unprognostic (2.72e-1)" "unprognostic (8.86e-2)" 18.6 14.1 15.9 20.3 17.8 17.7 18.0 25.5 20.5 16.1 15.7 17.4 19.1 18.9 18.6 15.0 15.5 15.6 19.7 15.1 20.2 18.0 27.6 17.0 22.5 18.9 18.1 19.1 19.5 19.0 9.5 17.5 20.2 19.0 20.7 18.4 16.1 14.9 22.1 24.0 20.5 18.1 16.5 19.7 23.9 17.7 19.7 21.3 18.4 15.9 21.6 14.7 12.7 24.4 18.8 17.9 22.4 22.5 38.0 34.9 22.3 27.1 28.1 19.7 24.0 49.7 44.9 39.3 51.0 34.4 26.5 40.3 31.9 25.7 32.6 22.3 14.8 64.5 15.4 25.7 32.6 36.8 47.3 35.4 18.2 40.4 39.3 26.3 33.3 33.9 37.2 35.9 28.7 35.4 31.5 36.5 20.9 37.7 22.7 20.0 32.5 40.2 21.6 43.1 20.3 21.1 39.2 33.5 12.3 24.2 44.8 16.6 34.6 29.0 19.0 25.1 22.8 10.5 13.8 36.4 16.1 41.6 30.4 14.2 9.5 9.7 7.5 10.5 5.8 5.1 5.6 5.4 9.8 3.5 6.0 5.4 9.6 6.5 12.8 5.7 7.0 4.8 15.9 17.8 25.5 20.5 15.1 20.2 18.9 18.1 20.2 16.5 19.7 24.4 28.7 12.8 31.9 45.7 27.5 26.8 22.0 20.4 25.6 19.5 26.3 18.0 18.2 10.0 27.8 14.7 18.8 20.3 30.6 25.5 5.9 19.8 18.0 23.7 35.3 20.9 18.6 26.9 46.2 28.5 19.8 24.2 41.8 31.7 10.8 25.7 19.2 44.6 21.9 16.8 56.3 20.1 30.5 27.9 23.1 15.2 17.1 33.2 24.9 36.5 32.4 20.5 24.7 55.8 80.9 27.0 18.3 21.4 42.0 23.1 29.0 11.5 37.5 16.8 19.7 23.4 23.6 35.3 22.0 30.3 39.2 24.8 31.0 26.0 20.3 26.1 UFC1 HSPC155 ENSG00000143222 "Ubiquitin-fold modifier conjugating enzyme 1" Q9Y3C8 1 161152776-161158856 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Respiratory ciliated cells: 703.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027481, HPA028722" Enhanced Approved "Nuclear speckles,Cytosol" NA NA 62000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 68: Epididymis - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "Nuclear speckles" Cytosol "HPA027481: AB_10599850, HPA028722: AB_10601674" "unprognostic (2.16e-1)" "unprognostic (6.17e-2)" "unprognostic (1.83e-1)" "unprognostic (8.25e-3)" "unprognostic (1.02e-1)" "unprognostic (1.18e-1)" "unprognostic (1.29e-3)" "unprognostic (2.15e-1)" "unprognostic (1.62e-2)" "unprognostic (3.40e-2)" "unprognostic (5.04e-2)" "unprognostic (1.86e-1)" "prognostic unfavorable (2.62e-6)" "unprognostic (3.49e-1)" "unprognostic (1.87e-1)" "unprognostic (2.13e-1)" "unprognostic (6.22e-2)" 85.3 112.1 135.3 76.1 139.3 134.5 134.0 137.6 167.5 100.4 138.9 114.5 112.6 91.7 170.6 100.2 209.3 103.2 111.9 135.4 149.2 129.5 115.4 87.8 107.6 136.4 139.0 140.7 164.7 148.0 102.4 92.9 143.0 106.5 141.9 85.1 126.0 112.2 101.0 110.5 103.1 108.4 139.6 79.1 116.3 56.3 137.6 110.4 108.9 108.3 128.6 125.9 76.8 142.3 140.7 119.8 107.8 129.9 137.5 226.7 223.5 124.7 154.0 122.7 111.8 165.0 268.6 183.2 232.8 180.7 77.3 65.7 89.1 127.2 96.1 154.4 238.6 109.4 163.0 200.9 139.8 233.4 271.9 190.4 202.6 152.5 104.6 207.4 227.9 189.4 183.0 123.8 159.8 161.3 126.1 234.9 198.9 387.9 128.5 152.6 80.8 258.6 248.4 158.2 112.9 196.2 108.1 324.2 163.8 176.8 148.2 482.1 165.6 90.5 92.2 90.7 196.1 233.3 322.2 177.5 140.7 164.8 119.7 137.3 156.7 104.5 174.7 164.1 212.8 209.3 185.0 188.2 192.4 164.1 161.9 175.4 28.4 208.3 121.6 206.4 274.4 268.1 135.3 139.3 137.6 167.5 135.4 149.2 136.4 139.0 143.0 139.6 137.6 142.3 107.0 70.5 85.3 18.3 151.9 99.8 173.3 244.6 106.4 57.4 174.2 177.5 117.6 147.3 171.6 104.8 41.7 253.8 170.8 150.8 440.3 224.2 131.0 421.2 96.6 123.3 204.5 124.7 8.7 380.8 386.9 99.2 111.6 113.2 119.7 143.1 116.7 106.2 244.7 47.1 7.7 240.0 205.4 150.7 138.5 392.3 105.0 132.0 131.6 9.4 229.3 161.8 195.7 11.1 13.3 265.5 189.1 91.0 182.6 148.0 243.5 380.9 703.0 72.0 65.7 86.3 106.7 96.6 42.4 125.2 120.9 431.9 155.1 124.4 193.7 218.6 UHMK1 "KIS, Kist" ENSG00000152332 "U2AF homology motif kinase 1" Q8TAS1 1 162497251-162529631 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, RNA-binding, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077624 Supported "Nucleoplasm,Nuclear speckles,Vesicles" NA No "Cluster 51: Monocytes - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Nuclear speckles" Vesicles "HPA077624: " "unprognostic (6.69e-2)" "unprognostic (1.28e-1)" "unprognostic (1.05e-1)" "unprognostic (1.46e-1)" "unprognostic (1.28e-1)" "unprognostic (1.33e-1)" "unprognostic (2.08e-2)" "unprognostic (8.16e-2)" "unprognostic (9.63e-2)" "unprognostic (1.82e-1)" "unprognostic (7.81e-3)" "unprognostic (9.10e-2)" "unprognostic (3.11e-1)" "unprognostic (3.44e-2)" "unprognostic (9.08e-2)" "unprognostic (8.77e-2)" "unprognostic (4.66e-2)" 26.8 23.3 21.2 23.3 24.6 40.3 19.3 18.1 21.2 15.1 16.6 19.2 19.1 11.7 14.1 13.3 14.4 13.7 11.6 26.0 28.3 31.2 38.1 17.5 30.8 24.9 28.5 11.9 11.0 27.8 7.8 17.1 28.3 16.2 19.6 10.5 13.5 18.5 25.8 11.9 23.4 10.8 19.8 25.4 20.0 12.2 26.1 24.6 19.4 25.9 28.9 18.1 10.5 19.4 61.9 28.4 14.6 35.8 40.7 31.9 32.7 79.7 43.2 63.9 45.7 18.6 37.8 50.2 67.8 60.0 31.2 34.9 28.2 44.1 102.4 69.1 20.4 49.8 34.3 16.9 31.3 73.4 55.5 33.0 45.8 63.2 59.9 44.6 37.4 34.2 44.1 67.7 111.4 26.0 39.3 19.4 19.4 46.1 37.8 24.9 64.9 41.9 42.6 62.8 26.4 24.3 70.5 64.6 52.2 19.9 56.0 81.0 58.5 72.7 41.0 50.8 112.6 69.2 103.5 58.0 60.5 35.3 67.3 3.6 2.0 2.4 4.8 5.3 4.9 3.2 3.5 4.0 2.3 3.6 3.5 4.0 1.3 3.7 6.1 2.6 3.1 2.6 21.2 24.6 18.1 21.2 26.0 28.3 24.9 28.5 28.3 19.8 26.1 19.4 37.6 19.2 41.2 20.9 75.6 29.4 33.7 38.5 34.7 24.4 39.4 20.2 35.1 40.0 53.8 53.3 12.5 26.2 81.0 53.9 56.7 27.6 55.6 35.1 35.7 33.4 33.5 51.6 37.0 23.2 38.1 25.5 43.3 44.4 45.7 23.3 31.1 85.1 30.0 23.5 27.4 34.1 48.8 73.5 47.5 58.4 21.5 60.0 28.4 33.7 58.0 14.6 74.2 20.6 29.5 40.4 33.0 19.5 47.2 59.9 60.8 62.2 50.9 23.0 0.0 29.2 27.8 25.1 29.6 45.2 24.6 22.4 69.4 31.4 39.3 58.3 UNC45A "GC-UNC45, SMAP-1" ENSG00000140553 "Unc-45 myosin chaperone A" Q9H3U1 15 90930180-90954093 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Myogenesis" "Chaperone, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039228 Approved Supported "Nuclear speckles,Cytosol" NA NA 17000 "Cluster 27: Non-specific - Gene expression" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "Nuclear speckles" Cytosol "HPA039228: AB_2676402" "unprognostic (1.46e-1)" "unprognostic (3.83e-2)" "unprognostic (4.51e-2)" "unprognostic (1.97e-1)" "unprognostic (2.68e-2)" "unprognostic (1.70e-3)" "prognostic unfavorable (7.72e-4)" "unprognostic (2.27e-2)" "unprognostic (1.58e-1)" "unprognostic (1.16e-1)" "unprognostic (1.98e-1)" "unprognostic (9.85e-2)" "prognostic favorable (7.46e-7)" "unprognostic (9.30e-2)" "unprognostic (1.74e-1)" "unprognostic (1.95e-1)" "unprognostic (2.28e-2)" 25.0 25.3 7.7 16.7 8.2 17.3 23.2 8.6 9.1 32.0 10.0 41.2 16.4 38.1 11.0 31.4 28.4 17.3 15.9 7.8 7.7 18.9 13.0 20.2 18.9 8.9 11.6 26.1 22.3 33.2 17.5 19.6 9.5 25.2 13.4 5.6 25.8 34.1 9.6 37.7 23.5 28.0 8.3 19.7 28.5 13.1 9.6 18.0 19.5 10.6 17.3 39.3 29.4 8.0 38.2 76.3 30.9 27.2 83.0 38.0 27.3 42.4 36.2 56.5 45.1 61.3 49.4 44.7 55.5 53.8 32.5 82.1 52.9 54.4 26.6 49.8 75.9 86.2 77.0 44.4 46.8 21.5 56.2 47.3 65.8 55.7 40.5 54.2 77.5 35.1 38.6 35.8 43.3 62.2 28.1 18.6 41.8 69.5 38.0 54.8 46.9 48.1 38.4 89.2 43.1 39.4 57.1 55.9 54.3 36.8 50.8 44.3 77.0 48.0 34.1 40.4 45.0 33.6 50.5 21.1 46.6 49.7 49.8 11.5 8.3 5.0 11.8 7.3 11.3 7.9 9.6 9.1 10.4 6.3 7.8 7.4 1.6 9.8 11.6 9.1 9.3 9.8 7.7 8.2 8.6 9.1 7.8 7.7 8.9 11.6 9.5 8.3 9.6 8.0 21.7 22.4 22.4 9.4 23.2 16.3 24.8 26.1 30.1 27.2 17.2 19.6 12.7 35.8 23.8 18.4 18.8 53.6 17.5 26.9 13.7 33.6 26.7 12.8 20.3 25.3 37.0 25.2 19.1 18.2 22.7 23.7 26.5 22.1 29.2 30.9 18.9 13.4 28.2 18.5 18.4 15.9 26.4 12.2 14.0 29.0 29.5 20.7 19.6 9.4 28.8 21.5 27.8 7.1 11.0 23.3 26.0 51.6 20.6 16.8 22.0 19.6 11.7 35.1 32.9 15.2 33.9 24.8 6.4 33.9 18.8 46.2 21.4 26.0 22.7 20.3 USP22 "KIAA1063, USP3L" ENSG00000124422 "Ubiquitin specific peptidase 22" Q9UPT9 17 20999596-21043760 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Chromatin regulator, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044980 Supported Approved "Nuclear speckles" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "HPA044980: AB_10794503" "unprognostic (7.24e-2)" "unprognostic (5.38e-2)" "unprognostic (7.67e-2)" "unprognostic (6.19e-2)" "unprognostic (4.72e-1)" "unprognostic (1.11e-2)" "prognostic unfavorable (9.66e-4)" "unprognostic (2.17e-2)" "unprognostic (7.81e-2)" "unprognostic (6.37e-2)" "unprognostic (1.07e-3)" "unprognostic (5.68e-2)" "prognostic favorable (1.53e-7)" "unprognostic (8.95e-2)" "unprognostic (1.93e-1)" "unprognostic (2.91e-1)" "unprognostic (1.79e-2)" 40.7 66.8 91.2 40.3 93.7 53.0 42.5 72.0 90.5 55.3 44.8 48.8 33.6 63.7 48.2 40.7 57.3 40.0 79.8 93.1 112.3 49.5 44.1 46.3 48.3 71.7 78.1 75.6 48.0 68.2 65.2 39.3 85.8 50.2 35.2 57.1 36.3 48.2 108.6 40.3 39.5 54.0 72.4 45.1 49.8 29.3 120.3 63.9 57.0 81.2 50.2 42.3 35.4 68.4 106.9 189.7 179.9 155.5 102.7 105.9 85.9 120.2 91.8 105.6 89.3 220.0 46.9 145.4 112.5 185.2 71.3 111.7 176.7 143.1 157.1 70.0 122.8 120.8 121.5 107.9 121.3 134.2 101.0 117.4 83.9 119.9 125.1 119.8 134.1 93.3 139.7 51.4 151.6 109.5 189.8 63.7 93.1 125.5 61.9 206.2 284.5 99.2 97.7 153.9 86.3 177.8 154.9 63.5 124.9 488.4 106.4 78.0 171.0 107.4 140.8 111.3 164.1 55.0 79.6 476.2 109.0 70.3 169.4 5.5 9.6 10.0 7.9 7.6 7.9 8.0 8.1 7.8 9.2 9.9 10.7 10.2 9.9 7.1 9.7 7.6 6.1 6.0 91.2 93.7 72.0 90.5 93.1 112.3 71.7 78.1 85.8 72.4 120.3 68.4 46.6 41.7 48.8 31.6 47.9 33.0 43.8 33.8 38.7 97.6 80.3 63.8 23.8 45.8 41.5 60.7 93.8 51.4 36.6 59.3 23.5 51.6 36.0 59.3 75.3 56.1 88.2 43.7 53.1 59.0 37.5 51.0 57.6 68.7 30.4 86.5 76.8 68.5 38.1 117.8 66.0 48.8 30.5 53.8 36.1 51.2 51.0 31.7 35.6 43.1 42.2 55.4 28.8 38.7 50.6 69.6 40.3 71.8 36.6 62.2 33.4 48.9 37.4 59.1 13.1 58.6 52.2 15.9 19.7 49.6 29.1 65.8 33.4 77.9 53.3 53.5 USP36 "FLJ12851, KIAA1453" ENSG00000055483 "Ubiquitin specific peptidase 36" Q9P275 17 78787381-78841441 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012082, HPA012395, HPA052860" Uncertain Supported Enhanced "Nucleoli,Nucleoli rim,Nuclear speckles" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 50: Non-specific - Ribosome" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 24: Non-specific - Transcription regulation" "Nucleoli, Nucleoli rim" "Nuclear speckles" "HPA012082: AB_1858682, HPA012395: , HPA052860: AB_2681974" "unprognostic (1.94e-2)" "unprognostic (2.80e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (5.18e-5)" "unprognostic (9.35e-2)" "unprognostic (1.98e-1)" "unprognostic (2.50e-3)" "unprognostic (1.35e-1)" "unprognostic (2.04e-1)" "unprognostic (1.33e-1)" "unprognostic (1.68e-2)" "unprognostic (2.78e-2)" "unprognostic (1.31e-2)" "unprognostic (1.45e-1)" "unprognostic (1.81e-1)" "unprognostic (4.03e-3)" "unprognostic (1.78e-1)" 43.9 37.9 20.0 21.5 21.9 46.6 32.9 29.3 23.9 32.6 27.5 31.2 13.4 26.8 22.9 25.0 34.2 18.7 30.2 21.4 20.6 34.4 30.3 36.1 20.6 22.6 21.3 67.4 44.5 18.1 50.3 26.0 21.5 36.2 15.8 26.3 24.9 13.1 30.3 40.4 26.6 16.3 19.4 30.7 31.2 22.2 21.2 15.1 31.6 11.7 20.5 29.3 29.8 30.1 42.7 50.3 14.6 26.9 30.5 33.7 27.8 34.1 34.5 32.1 21.5 49.2 21.0 54.0 16.9 30.6 34.8 30.6 34.5 25.4 57.0 13.0 52.1 49.4 81.0 51.9 31.3 54.7 26.0 29.5 41.0 45.8 101.6 24.7 28.3 24.1 40.0 55.3 26.8 32.6 50.1 55.1 22.6 31.6 39.9 38.1 31.8 36.3 20.2 44.1 42.8 25.8 24.5 112.5 63.7 31.3 29.2 34.4 24.3 75.2 35.3 44.3 61.1 40.7 17.4 66.1 29.6 41.9 24.0 10.1 3.0 2.4 5.5 4.2 6.5 5.1 5.2 4.8 1.8 4.7 5.7 5.6 4.3 4.5 2.7 9.7 3.8 1.9 20.0 21.9 29.3 23.9 21.4 20.6 22.6 21.3 21.5 19.4 21.2 30.1 27.4 12.8 37.4 23.5 55.9 51.7 28.4 8.2 40.9 33.2 18.1 16.9 14.1 18.6 18.8 14.7 33.3 8.3 66.3 14.4 5.9 10.2 20.7 22.3 24.0 28.4 18.5 14.7 19.0 9.6 11.3 26.6 25.0 42.7 20.3 12.8 12.1 16.5 43.3 26.9 22.5 18.6 10.2 24.5 72.8 8.5 11.8 49.4 30.2 10.3 14.9 13.2 16.5 13.6 19.8 13.2 8.4 12.4 57.1 32.4 7.3 5.0 11.1 32.1 6.6 22.1 23.1 18.4 16.5 24.4 43.3 12.9 73.6 13.1 18.6 22.2 USP43 FLJ30626 ENSG00000154914 "Ubiquitin specific peptidase 43" Q70EL4 17 9644698-9729687 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 37.9;Excitatory neurons: 35.5;Glandular and luminal cells: 52.5;Oligodendrocyte precursor cells: 73.4;Syncytiotrophoblasts: 73.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 11.7;SK-BR-3: 8.1;T-47d: 9.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA023389, HPA027762, HPA027763" Uncertain Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Nuclear speckles" "HPA023389: AB_1858691, HPA027762: AB_10603001, HPA027763: " "unprognostic (1.39e-1)" "unprognostic (1.75e-2)" "unprognostic (1.07e-1)" "unprognostic (2.30e-3)" "unprognostic (1.08e-1)" "unprognostic (5.24e-2)" "unprognostic (2.04e-1)" "unprognostic (6.40e-3)" "unprognostic (2.26e-1)" "unprognostic (3.05e-3)" "unprognostic (2.41e-2)" "unprognostic (7.49e-2)" "unprognostic (5.95e-2)" "prognostic favorable (5.39e-4)" "unprognostic (3.24e-1)" "unprognostic (2.06e-1)" "unprognostic (3.28e-1)" 0.3 0.2 2.6 0.6 3.4 0.7 1.9 0.8 4.1 2.9 2.9 3.5 4.2 1.9 1.0 6.5 4.2 1.2 0.0 3.3 1.4 4.0 9.1 3.2 0.1 2.5 4.6 0.1 5.0 1.1 3.5 8.3 2.5 9.8 3.2 1.4 4.3 2.2 0.0 2.2 3.5 0.2 2.1 0.3 2.1 3.2 2.3 0.3 1.7 0.0 0.7 1.1 2.4 2.5 5.6 1.4 0.0 0.5 0.0 0.0 11.7 0.1 0.2 0.6 1.6 2.8 4.5 0.0 1.8 0.2 2.5 6.8 0.6 5.3 0.6 3.6 1.8 0.3 3.0 1.0 0.1 0.5 0.0 0.0 6.8 0.3 2.8 0.3 0.0 0.8 0.0 0.0 0.0 2.6 0.9 4.6 0.7 4.8 0.3 3.6 0.0 0.8 4.1 3.0 0.7 0.0 2.4 8.1 1.0 3.7 9.9 1.4 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.7 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.6 3.4 0.8 4.1 3.3 1.4 2.5 4.6 2.5 2.1 2.3 2.5 0.0 3.2 3.1 1.6 0.3 4.7 7.8 4.6 5.2 0.5 7.0 2.4 0.6 4.3 7.4 11.0 6.2 26.2 0.6 14.3 1.9 4.4 1.1 37.9 4.2 0.5 2.4 3.2 35.5 4.7 23.7 0.8 7.7 52.5 0.0 0.9 0.4 15.6 2.7 0.0 4.0 8.3 2.0 0.9 0.3 1.1 0.0 0.6 5.4 0.0 0.3 8.4 0.0 73.4 1.2 11.3 3.5 0.0 0.2 10.6 8.7 1.8 30.2 1.5 0.0 0.0 1.0 1.5 0.3 12.3 3.3 73.2 0.7 0.0 9.7 11.8 VAX2 DRES93 ENSG00000116035 "Ventral anterior homeobox 2" Q9UIW0 2 70900576-70965373 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 5.4;retina: 11.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 9.5;Cone photoreceptor cells: 16.7;Horizontal cells: 11.8;Muller glia cells: 7.6;Rod photoreceptor cells: 19.5" "Cancer enhanced" "Detected in many" "endometrial cancer: 7.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 4.7;MCF7: 5.6;RH-30: 4.6;SCLC-21H: 4.6;SH-SY5Y: 5.6" "Not detected" "Not detected" "Region enhanced" "Detected in some" "hypothalamus: 3.2" HPA009708 Approved "Nuclear speckles" NA NA "Cluster 77: Retina - Visual perception" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 46: Photoreceptor cells - Phototransduction" "Nuclear speckles" "HPA009708: AB_2668261" "unprognostic (1.56e-1)" "unprognostic (1.45e-1)" "unprognostic (1.96e-2)" "unprognostic (3.16e-2)" "unprognostic (1.63e-2)" "unprognostic (2.17e-1)" "unprognostic (3.52e-2)" "unprognostic (7.23e-3)" "unprognostic (2.42e-1)" "unprognostic (1.98e-1)" "unprognostic (3.81e-1)" "unprognostic (2.16e-1)" "unprognostic (7.74e-3)" "unprognostic (6.63e-3)" "unprognostic (4.65e-1)" "unprognostic (6.67e-3)" "unprognostic (2.18e-2)" 1.5 0.4 1.8 0.1 1.0 0.0 1.1 5.4 1.6 0.9 0.6 0.6 0.0 1.0 0.0 0.4 0.7 0.0 0.6 1.9 2.6 0.4 0.0 0.5 0.0 0.9 1.0 0.7 1.2 0.2 0.9 0.2 1.0 0.7 0.0 11.1 0.8 0.0 0.5 1.2 0.3 0.3 0.7 0.0 0.2 0.2 1.6 0.0 0.2 0.1 0.0 0.5 0.4 1.0 1.5 3.6 0.8 4.7 1.2 0.7 2.6 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 2.1 1.5 0.2 1.8 0.0 0.1 0.0 3.0 0.0 0.0 2.1 0.6 0.0 0.0 1.2 0.0 0.2 0.0 1.3 0.4 0.2 0.0 0.0 1.8 5.6 0.0 0.0 2.0 0.0 0.0 0.0 4.6 0.0 1.5 1.2 4.6 5.6 3.7 0.0 2.1 0.1 2.1 0.2 0.9 2.2 0.5 1.1 0.9 0.0 0.0 0.0 1.1 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.0 5.4 1.6 1.9 2.6 0.9 1.0 1.0 0.7 1.6 1.0 3.2 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 9.5 1.4 1.4 0.1 0.0 0.1 0.0 16.7 0.1 0.1 0.2 1.9 1.2 0.1 0.0 0.1 1.5 0.0 0.0 0.6 0.6 0.4 1.4 0.0 0.0 0.0 0.0 1.1 0.1 0.0 11.8 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 1.8 0.0 4.2 7.6 0.0 2.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 19.5 0.0 0.8 0.8 0.0 0.2 0.0 0.0 0.1 0.1 0.8 0.1 0.0 VPS72 "Swc2, TCFL1, YL-1, YL1" ENSG00000163159 "Vacuolar protein sorting 72 homolog" Q15906 1 151176304-151195321 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065709 Approved "Nuclear speckles" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "HPA065709: AB_2685540" "unprognostic (2.55e-1)" "unprognostic (3.79e-1)" "unprognostic (3.10e-1)" "unprognostic (4.50e-2)" "unprognostic (2.16e-2)" "unprognostic (7.00e-2)" "prognostic unfavorable (4.41e-6)" "unprognostic (4.10e-2)" "unprognostic (2.25e-1)" "unprognostic (1.10e-2)" "unprognostic (9.58e-2)" "unprognostic (1.50e-1)" "unprognostic (7.92e-2)" "unprognostic (4.52e-2)" "unprognostic (4.92e-2)" "unprognostic (4.49e-2)" "unprognostic (1.30e-1)" 23.8 21.0 33.3 17.0 34.1 12.9 22.7 35.3 39.7 27.5 30.0 26.8 16.8 28.1 19.0 25.0 23.5 15.0 25.4 32.9 35.9 24.9 17.9 18.7 21.2 34.2 33.6 25.8 21.5 21.2 19.1 22.3 34.6 25.8 16.2 18.2 23.5 18.1 56.3 24.3 20.5 24.2 33.6 23.5 23.8 18.7 34.3 27.9 20.0 32.3 26.3 32.2 23.6 36.5 60.7 41.0 92.8 66.9 40.1 35.0 79.5 64.2 33.8 50.4 36.4 43.7 49.4 60.6 77.3 48.7 35.0 56.0 69.1 41.4 38.0 72.2 75.4 52.3 31.0 30.2 55.7 77.8 46.0 28.5 56.8 57.4 47.5 52.8 66.7 74.3 100.2 44.5 40.3 103.3 67.0 54.8 108.5 107.5 69.2 73.2 52.9 95.3 47.1 30.5 65.5 116.8 44.1 67.6 78.9 86.6 76.5 114.4 63.2 26.5 44.9 42.7 82.3 82.5 124.9 96.4 43.4 52.9 49.9 63.3 48.8 82.4 57.2 47.5 55.4 65.8 50.9 49.3 55.3 53.9 50.3 45.6 35.7 75.3 40.6 35.2 67.5 58.3 33.3 34.1 35.3 39.7 32.9 35.9 34.2 33.6 34.6 33.6 34.3 36.5 23.3 6.4 9.1 7.5 21.9 28.4 28.6 40.0 28.5 13.7 24.8 32.1 15.1 24.3 26.8 23.9 4.2 57.6 19.1 24.6 64.6 49.9 12.2 15.2 18.1 25.2 20.3 30.9 6.3 46.4 53.5 24.3 20.9 17.4 31.7 25.4 25.0 18.1 32.0 15.2 6.9 30.6 63.1 22.9 18.8 9.7 25.1 17.7 42.7 2.8 33.8 32.8 29.9 4.5 9.1 59.8 30.5 24.8 13.5 31.4 28.6 35.4 15.7 12.9 52.6 23.3 40.7 39.5 30.4 23.5 31.7 63.1 24.8 16.1 27.1 35.5 VXN "C8orf46, MGC33510" ENSG00000169085 Vexin Q8TAG6 8 66493520-66518524 "Predicted intracellular proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 123.8" "Cell type enhanced" "Detected in some" "Breast glandular cells: 1.1;Proximal tubular cells: 3.4;Syncytiotrophoblasts: 1.0" "Cancer enriched" "Detected in many" 6 "glioma: 16.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 4.5;GAMG: 5.4;HBF TERT88: 3.9;LHCN-M2: 4.4;T-47d: 5.8;WM-115: 4.5" "Group enriched" "Detected in all" 8 "amygdala: 159.7;basal ganglia: 78.9;cerebral cortex: 298.2;hippocampal formation: 219.3;white matter: 199.5" "Low region specificity" "Detected in all" HPA075134 Approved "Nuclear speckles" NA NA "Cluster 65: Brain - Ion transport" "Cluster 6: T47d - Mammary gland" "Cluster 7: Non-specific - Mitochondria" "Nuclear speckles" "HPA075134: AB_2686736" "unprognostic (6.87e-2)" "unprognostic (7.85e-2)" "unprognostic (2.01e-1)" "unprognostic (8.36e-4)" "unprognostic (1.02e-1)" "unprognostic (1.51e-1)" "unprognostic (7.53e-4)" "unprognostic (7.87e-3)" "unprognostic (1.45e-1)" "unprognostic (1.19e-1)" "unprognostic (8.22e-2)" "unprognostic (1.82e-1)" "unprognostic (6.36e-3)" "unprognostic (3.53e-4)" "unprognostic (1.86e-1)" "unprognostic (4.98e-2)" "unprognostic (2.91e-2)" 0.3 0.5 61.0 0.3 72.1 0.0 0.5 52.0 87.2 0.9 21.7 1.8 0.0 0.7 1.3 0.0 0.5 0.2 0.3 123.8 47.4 0.6 1.4 0.3 0.0 53.1 56.2 0.3 0.6 0.4 0.4 0.0 56.0 1.5 0.3 0.2 0.1 5.4 0.5 0.2 0.5 1.1 53.4 0.1 1.2 0.3 53.7 0.0 0.2 0.0 0.3 0.3 0.4 84.5 2.7 0.1 1.0 1.3 0.1 0.1 0.0 0.2 0.4 1.2 1.3 0.1 4.5 0.0 0.1 2.9 5.4 0.1 0.0 0.0 3.9 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.1 0.2 0.3 0.0 0.0 0.0 0.1 4.4 0.3 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.0 1.9 0.1 0.2 0.0 0.1 0.1 3.0 0.1 5.8 0.0 0.0 0.4 0.9 0.0 1.9 2.0 1.1 0.0 1.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.0 72.1 52.0 87.2 123.8 47.4 53.1 56.2 56.0 53.4 53.7 84.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.9 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.6 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.4 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.3 0.0 0.0 WDR17 ENSG00000150627 "WD repeat domain 17" Q8IZU2 4 176065841-176182818 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 11.5;retina: 28.6" "Cell type enhanced" "Detected in many" "Astrocytes: 183.1;Cone photoreceptor cells: 64.6;Excitatory neurons: 222.8;Inhibitory neurons: 127.6;Oligodendrocyte precursor cells: 125.2" "Cancer enhanced" "Detected in some" "glioma: 1.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 5.6;SCLC-21H: 7.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042766, HPA054501" Approved Approved "Nuclear speckles" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear speckles" "HPA042766: AB_10806372, HPA054501: AB_2732586" "unprognostic (3.41e-4)" "unprognostic (1.72e-1)" "unprognostic (1.20e-1)" "unprognostic (6.43e-7)" "unprognostic (3.53e-1)" "unprognostic (1.40e-1)" "unprognostic (2.07e-1)" "unprognostic (1.91e-1)" "unprognostic (8.62e-2)" "unprognostic (1.42e-1)" "unprognostic (1.39e-3)" "unprognostic (6.04e-4)" "unprognostic (3.66e-4)" "unprognostic (9.25e-3)" "unprognostic (4.63e-2)" "unprognostic (7.32e-3)" "unprognostic (8.24e-3)" 0.8 2.9 4.5 0.9 7.9 0.6 1.3 2.9 7.6 1.4 0.0 2.5 0.5 1.8 2.4 0.6 1.9 1.1 0.8 8.5 2.5 2.5 0.3 1.4 0.6 0.0 0.0 1.8 2.2 7.0 11.5 0.1 0.8 0.8 1.1 28.6 0.8 0.8 0.2 0.4 1.2 1.0 0.0 1.1 1.3 1.9 2.3 0.3 4.3 0.3 0.5 1.4 1.0 3.4 0.0 2.5 5.6 0.0 0.1 0.4 0.2 0.1 0.0 0.6 1.9 0.2 0.0 3.7 0.0 0.1 3.0 0.0 2.4 1.4 0.5 0.0 2.0 0.0 0.5 0.0 0.2 2.0 2.8 0.8 0.7 0.1 0.3 0.7 0.0 4.3 0.0 0.3 0.5 1.1 2.4 0.1 1.2 0.0 1.4 0.0 2.5 0.0 0.2 0.0 7.6 4.8 0.0 1.4 3.8 0.7 0.4 0.0 0.0 0.8 1.0 0.0 3.4 2.7 1.8 2.3 4.2 0.0 1.4 0.4 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.2 0.0 0.1 0.0 0.0 4.5 7.9 2.9 7.6 8.5 2.5 0.0 0.0 0.8 0.0 2.3 3.4 0.3 0.0 5.8 183.1 2.4 0.1 0.5 0.1 3.4 16.9 0.6 0.9 0.9 1.5 1.3 0.0 64.6 0.0 0.0 0.1 1.9 0.3 1.5 0.5 0.6 0.7 4.8 1.7 222.8 0.6 0.0 2.0 0.0 0.0 3.8 0.1 2.2 0.1 0.2 21.9 127.6 0.1 0.0 0.6 0.6 1.5 0.9 1.3 1.8 23.4 0.6 10.2 0.0 125.2 40.0 0.2 0.0 1.5 0.2 0.4 0.0 11.6 7.7 36.6 0.0 3.0 1.9 2.7 5.2 0.4 0.0 0.0 0.3 1.4 0.1 0.3 WDR90 "C16orf15, C16orf16, C16orf17, C16orf18, C16orf19, FLJ36483, KIAA1924, POC16" ENSG00000161996 "WD repeat domain 90" Q96KV7 16 649311-667833 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 61.2" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 32.3;Respiratory ciliated cells: 57.6;Rod photoreceptor cells: 34.7;Spermatocytes: 34.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HeLa: 57.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA049362, HPA061785" Approved Approved "Nuclear speckles" NA NA "Cluster 37: B-cells - Transcription" "Cluster 43: Testis - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "Nuclear speckles" "HPA049362: AB_2680728, HPA061785: AB_2684606" "unprognostic (1.97e-2)" "unprognostic (1.50e-2)" "unprognostic (1.72e-1)" "unprognostic (7.34e-3)" "unprognostic (3.89e-2)" "prognostic favorable (2.70e-4)" "unprognostic (2.67e-2)" "unprognostic (8.28e-2)" "unprognostic (5.23e-2)" "unprognostic (1.02e-1)" "unprognostic (9.55e-2)" "unprognostic (9.96e-3)" "unprognostic (2.84e-3)" "unprognostic (8.26e-2)" "unprognostic (3.08e-1)" "unprognostic (4.25e-2)" "unprognostic (4.48e-2)" 8.1 16.3 8.7 3.4 8.8 11.5 10.9 9.5 12.3 17.0 9.9 11.4 5.9 13.3 3.2 10.5 22.1 3.6 9.7 8.9 8.7 16.4 10.9 10.0 4.0 9.2 9.3 21.5 15.7 4.4 25.9 2.5 8.9 15.1 2.2 4.6 9.5 5.5 4.6 9.9 9.3 2.2 8.5 7.4 11.7 61.2 9.1 5.1 22.2 1.4 2.0 10.0 10.5 9.4 10.2 14.1 7.8 18.8 2.9 1.9 0.5 7.4 2.8 5.4 6.3 18.2 14.0 8.8 5.7 2.3 0.1 22.0 3.8 6.0 1.2 15.0 13.7 2.9 57.2 16.9 0.8 15.7 13.4 3.8 4.7 10.8 2.5 2.0 4.0 13.7 1.0 21.9 2.4 7.4 12.5 15.0 7.6 8.4 4.4 34.7 3.1 14.6 6.0 9.4 14.6 15.3 6.8 13.9 1.6 0.5 28.7 12.9 4.3 13.0 13.1 14.3 9.8 22.0 10.4 9.7 3.8 8.5 8.6 0.0 0.0 0.0 0.0 0.2 0.0 1.2 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 8.7 8.8 9.5 12.3 8.9 8.7 9.2 9.3 8.9 8.5 9.1 9.4 4.5 0.0 9.1 10.4 1.1 3.4 2.8 4.5 3.4 9.4 9.7 10.4 4.9 14.3 6.9 9.2 14.6 2.8 0.7 10.1 0.0 5.4 5.6 32.3 6.5 4.3 1.2 2.5 5.0 3.8 2.6 5.9 12.2 9.9 0.0 15.1 1.8 4.5 2.7 11.8 5.5 6.9 0.0 0.8 2.5 4.0 6.2 2.2 3.6 5.6 0.3 5.6 0.0 1.5 2.6 4.5 3.1 4.5 1.3 2.7 3.0 2.1 57.6 34.7 6.6 8.3 5.1 34.2 20.7 3.0 2.3 2.5 1.5 8.3 10.8 2.0 WRN "RECQ3, RECQL2" ENSG00000165392 "WRN RecQ like helicase" Q14191 8 31033788-31176138 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Exonuclease, Helicase, Hydrolase, Multifunctional enzyme, Nuclease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 74.7;Early spermatids: 116.3;Oligodendrocytes: 88.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028661 Approved Supported "Nuclear speckles" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Nuclear speckles" "HPA028661: AB_10602255" "unprognostic (8.73e-2)" "unprognostic (9.33e-2)" "unprognostic (1.51e-3)" "unprognostic (3.85e-2)" "unprognostic (1.41e-1)" "unprognostic (1.85e-2)" "unprognostic (2.21e-3)" "unprognostic (1.25e-1)" "unprognostic (1.07e-1)" "unprognostic (1.16e-2)" "unprognostic (1.27e-2)" "unprognostic (6.63e-2)" "unprognostic (1.53e-2)" "unprognostic (6.51e-2)" "unprognostic (2.49e-1)" "unprognostic (1.00e-2)" "unprognostic (2.66e-1)" 3.0 3.6 1.7 3.2 1.7 8.2 4.8 4.1 2.4 3.0 2.6 3.5 1.5 6.4 3.2 2.7 2.9 2.4 1.7 1.6 1.7 2.1 2.5 2.4 2.5 1.8 2.1 5.2 2.6 2.0 2.1 3.6 1.8 3.5 2.9 4.4 3.5 2.6 2.1 4.1 2.5 4.2 1.2 3.1 2.3 3.0 1.9 3.2 3.2 2.2 3.0 2.6 2.3 3.1 4.4 5.9 10.8 5.3 6.7 9.8 5.0 4.7 4.9 6.4 6.6 2.7 1.5 10.0 4.6 4.3 4.4 2.4 6.4 3.8 9.7 3.3 4.3 9.6 4.9 4.4 5.4 8.7 4.3 7.1 3.7 3.6 6.2 3.9 7.7 6.1 14.5 5.0 6.8 2.0 17.5 6.6 7.7 5.1 3.2 7.5 7.5 6.7 2.9 4.4 3.3 5.2 6.9 2.7 3.8 4.9 2.9 5.3 9.1 6.2 3.8 3.1 4.9 1.4 3.0 14.6 5.5 3.8 4.2 0.8 0.2 0.3 0.3 0.1 0.4 0.5 0.5 0.3 0.2 0.5 0.3 0.4 0.3 1.1 0.1 0.1 0.3 0.1 1.7 1.7 4.1 2.4 1.6 1.7 1.8 2.1 1.8 1.2 1.9 3.1 17.5 9.6 10.6 74.7 15.1 13.5 11.7 5.3 18.8 14.5 14.7 10.5 7.5 15.7 8.8 16.5 22.9 7.1 18.0 5.3 1.9 6.7 116.3 15.8 32.3 12.5 2.4 49.2 59.7 9.8 5.7 15.2 21.9 17.1 2.5 18.5 7.1 9.7 5.3 15.2 54.9 13.8 8.2 5.3 6.6 12.8 19.0 7.8 10.6 51.5 6.9 14.3 4.1 61.3 88.6 9.1 4.2 14.3 16.6 15.3 3.9 2.7 10.0 19.8 6.6 20.2 15.3 10.9 19.2 10.1 10.2 5.6 13.0 15.2 7.7 11.0 WTAP "KIAA0105, MGC3925, Mum2" ENSG00000146457 "WT1 associated protein" Q15007 6 159725585-159756319 "Predicted intracellular proteins" "Cell cycle, mRNA processing, mRNA splicing" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 560.1;Suprabasal keratinocytes: 455.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010550 Supported Enhanced "Nuclear speckles" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Nuclear speckles" "HPA010550: AB_1858866" "unprognostic (9.57e-2)" "unprognostic (1.58e-2)" "unprognostic (5.10e-2)" "unprognostic (2.32e-1)" "unprognostic (7.19e-2)" "unprognostic (1.62e-1)" "prognostic unfavorable (6.57e-6)" "unprognostic (8.65e-2)" "unprognostic (3.75e-1)" "prognostic unfavorable (7.51e-4)" "unprognostic (7.72e-2)" "unprognostic (4.92e-2)" "prognostic unfavorable (3.01e-5)" "unprognostic (7.92e-2)" "unprognostic (2.62e-1)" "unprognostic (4.00e-2)" "unprognostic (1.32e-2)" 86.2 63.7 35.3 62.3 35.7 245.1 74.9 40.0 41.3 71.7 41.3 54.6 34.9 64.7 65.1 65.0 64.2 52.2 54.3 35.0 42.5 54.8 50.7 68.6 77.5 38.2 38.3 70.5 63.3 53.2 49.8 61.8 39.4 65.1 55.2 35.6 62.0 44.6 179.7 72.5 61.6 51.5 36.9 67.0 58.5 34.9 40.1 89.7 57.4 67.4 80.7 102.6 65.1 41.2 55.5 51.1 115.8 100.2 136.5 147.7 67.1 86.2 299.4 108.7 145.4 95.7 49.0 126.8 50.8 92.6 238.4 70.4 112.2 94.3 138.1 70.0 71.9 135.0 46.7 144.2 108.4 116.1 75.4 172.0 94.7 120.0 155.0 82.6 81.6 130.7 149.1 114.2 116.0 53.5 170.5 165.0 91.9 88.6 44.2 107.4 74.3 94.4 114.0 62.6 104.5 74.5 158.2 83.5 45.7 77.5 41.3 152.6 72.6 70.0 81.4 100.1 125.0 83.9 109.6 206.5 67.8 120.9 76.8 46.6 24.5 31.0 28.1 31.7 31.7 33.1 33.9 34.3 29.1 27.5 29.9 31.4 42.9 32.1 38.3 24.3 40.2 20.2 35.3 35.7 40.0 41.3 35.0 42.5 38.2 38.3 39.4 36.9 40.1 41.2 131.1 35.3 57.3 31.3 138.1 419.0 198.0 52.9 113.8 30.0 144.2 123.6 58.1 74.4 39.9 60.7 35.5 107.3 138.5 61.2 86.1 128.1 47.1 86.4 125.5 118.8 61.6 59.3 41.5 81.4 126.7 226.9 97.9 171.9 40.0 56.7 58.2 90.5 75.4 37.0 36.6 65.7 24.4 99.7 560.1 50.7 65.3 168.6 243.7 33.7 113.7 49.7 88.6 44.7 57.0 75.8 59.7 50.8 111.5 307.5 49.6 106.5 35.3 36.2 72.3 222.2 124.5 93.8 73.9 113.0 455.3 149.3 138.6 54.7 74.0 150.9 XYLB "FLJ10343, FLJ12539" ENSG00000093217 Xylulokinase O75191 3 38346760-38421348 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Xylose metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 33.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 39.3;Hepatocytes: 49.3;Inhibitory neurons: 35.9;Proximal tubular cells: 31.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 5.4" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA037863, HPA038415" Uncertain Approved "Nuclear speckles" NA NA 12000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles" "HPA037863: AB_10672729, HPA038415: AB_10672592" "unprognostic (2.48e-1)" "unprognostic (9.72e-2)" "unprognostic (3.42e-2)" "unprognostic (6.25e-2)" "unprognostic (7.52e-2)" "unprognostic (5.19e-2)" "unprognostic (5.82e-2)" "unprognostic (1.26e-3)" "unprognostic (6.55e-2)" "unprognostic (2.22e-1)" "unprognostic (6.91e-3)" "unprognostic (4.63e-2)" "prognostic favorable (8.57e-4)" "unprognostic (3.26e-1)" "unprognostic (2.06e-1)" "unprognostic (5.78e-2)" "unprognostic (3.37e-2)" 1.4 2.3 1.3 1.5 1.0 2.2 3.0 5.4 2.0 1.6 0.0 4.1 5.8 1.9 0.8 1.9 1.1 1.6 0.5 0.9 0.7 11.4 33.4 0.7 1.0 0.9 0.2 2.2 2.5 1.1 0.8 0.9 1.1 1.6 4.6 2.1 5.3 0.9 0.6 1.5 6.4 1.4 0.0 1.0 3.5 1.0 0.9 1.6 0.7 0.5 0.8 1.2 1.3 0.6 3.5 6.4 2.8 6.7 4.2 4.3 6.3 5.9 2.0 4.5 4.4 8.2 3.6 3.7 1.4 7.6 5.4 2.5 8.1 2.5 5.6 5.0 6.2 7.5 5.0 24.1 2.2 10.1 7.7 3.0 5.2 5.8 2.7 1.9 4.7 8.5 18.0 6.2 5.0 2.4 8.3 1.4 3.8 8.9 7.9 4.2 5.5 5.0 0.6 6.3 3.6 3.2 3.7 16.0 12.7 2.4 7.2 6.1 2.6 9.0 7.3 15.6 2.5 3.5 6.6 8.5 5.4 9.1 7.2 1.4 0.9 2.0 0.6 1.6 0.5 0.2 0.5 0.3 1.7 0.3 0.6 0.6 1.9 0.5 1.4 0.6 1.5 0.4 1.3 1.0 5.4 2.0 0.9 0.7 0.9 0.2 1.1 0.0 0.9 0.6 1.0 0.0 1.3 14.0 0.9 0.9 2.1 1.8 6.8 3.2 3.0 3.4 1.1 2.8 1.5 0.0 0.0 4.3 1.7 3.8 1.9 1.0 0.5 0.4 3.5 1.8 0.0 3.4 39.3 3.0 3.8 2.3 8.6 1.0 0.0 1.3 1.1 49.3 4.0 0.0 35.9 5.7 2.0 1.0 3.7 1.0 1.5 2.0 0.0 17.8 1.0 0.4 0.0 17.1 17.7 1.3 5.8 1.9 1.6 1.7 13.0 31.7 1.3 5.1 0.0 2.4 1.4 0.5 2.7 4.1 0.9 1.4 0.8 1.8 5.1 2.1 YLPM1 "C14orf170, PPP1R169, ZAP" ENSG00000119596 "YLP motif containing 1" P49750 14 74763316-74859435 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048070, HPA061123" Uncertain Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nuclear speckles" "HPA048070: AB_2680247, HPA061123: AB_2684435" "unprognostic (2.17e-1)" "unprognostic (3.32e-2)" "unprognostic (3.95e-1)" "unprognostic (2.98e-1)" "unprognostic (3.79e-2)" "unprognostic (7.64e-2)" "unprognostic (3.22e-3)" "unprognostic (8.74e-2)" "unprognostic (3.60e-2)" "unprognostic (2.56e-1)" "unprognostic (7.83e-3)" "unprognostic (6.63e-2)" "prognostic favorable (6.08e-7)" "unprognostic (1.09e-2)" "unprognostic (2.41e-1)" "unprognostic (1.87e-1)" "unprognostic (1.60e-1)" 13.3 13.0 12.5 10.4 12.8 17.6 13.8 18.1 15.6 18.0 2.8 12.9 7.0 16.1 12.9 12.7 15.9 8.5 11.4 10.9 16.4 10.6 8.5 11.2 13.1 9.5 10.0 22.1 13.1 12.1 15.6 11.2 9.3 14.0 9.2 17.6 15.0 10.3 15.0 15.3 13.4 9.4 4.8 13.4 11.9 18.5 12.3 14.9 16.8 7.4 11.9 14.0 15.0 12.8 28.3 28.9 31.8 7.1 25.2 20.8 18.0 18.3 18.7 18.9 18.9 25.8 19.6 40.9 13.4 20.8 13.7 26.1 28.6 19.6 30.2 24.6 17.3 29.4 19.8 20.0 12.2 22.3 21.9 19.0 13.5 20.9 16.5 23.3 25.3 22.9 24.1 18.9 23.5 29.9 26.4 24.4 20.0 19.2 26.1 40.5 31.8 14.3 16.5 37.2 24.2 23.8 29.4 20.2 8.3 21.8 22.9 17.4 37.0 22.6 28.3 15.6 23.9 23.3 24.8 43.6 19.3 17.3 17.2 0.3 1.4 1.5 1.5 1.6 1.7 1.9 1.3 1.3 1.1 1.9 1.8 1.8 1.0 2.3 1.5 3.4 1.1 1.4 12.5 12.8 18.1 15.6 10.9 16.4 9.5 10.0 9.3 4.8 12.3 12.8 26.8 25.6 34.3 54.2 32.7 19.9 11.2 13.3 27.9 42.0 27.7 25.3 45.9 14.3 25.0 9.2 41.7 19.7 32.4 15.7 1.9 15.7 35.4 26.8 36.0 29.7 20.4 23.5 86.7 15.5 13.5 24.4 23.0 28.6 17.7 54.1 21.8 16.8 19.1 52.2 84.3 18.9 12.2 22.6 12.3 17.7 33.8 19.5 5.4 51.5 28.6 24.6 32.0 68.9 76.5 18.0 13.3 48.5 30.3 18.9 14.0 14.7 33.0 30.8 19.7 35.5 24.8 62.8 49.0 29.2 23.3 15.7 29.3 32.5 21.6 13.2 ZBTB18 "C2H2-171, RP58, TAZ-1, ZNF238" ENSG00000179456 "Zinc finger and BTB domain containing 18" Q99592 1 244048939-244057476 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 172.8;skeletal muscle: 85.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 51.8;Muller glia cells: 52.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.3" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 217.5" "HPA024656, HPA074019" Enhanced Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoplasm, Nuclear speckles" "HPA024656: , HPA074019: " "unprognostic (3.48e-3)" "unprognostic (9.17e-3)" "unprognostic (3.69e-3)" "prognostic favorable (1.34e-4)" "unprognostic (6.83e-2)" "unprognostic (4.52e-2)" "unprognostic (2.13e-1)" "unprognostic (1.15e-2)" "unprognostic (1.15e-2)" "unprognostic (8.43e-2)" "unprognostic (1.01e-2)" "unprognostic (2.60e-1)" "unprognostic (6.28e-2)" "unprognostic (9.37e-2)" "unprognostic (2.07e-2)" "unprognostic (6.54e-3)" "prognostic favorable (6.78e-6)" 9.8 6.3 36.2 14.9 45.4 28.2 9.0 172.8 57.5 7.4 20.3 9.2 13.2 7.2 18.5 5.8 8.6 7.4 12.2 66.1 13.5 11.9 19.0 10.0 18.2 18.0 18.1 7.2 24.6 6.2 4.9 9.4 24.7 10.1 10.8 42.2 10.6 11.5 85.5 8.3 14.6 6.1 19.0 20.2 11.4 22.3 18.9 41.9 8.4 37.5 15.7 10.0 5.4 29.8 23.7 8.2 31.2 1.2 4.0 4.1 21.7 13.0 9.6 20.5 12.4 6.3 18.7 17.9 1.2 25.2 6.6 2.4 20.1 6.4 25.5 6.4 17.7 3.0 3.1 3.0 6.3 3.8 9.1 3.5 5.3 12.3 7.7 24.7 22.5 19.3 2.3 7.5 24.5 0.3 31.4 15.2 16.1 7.3 3.6 9.1 21.2 5.1 13.1 8.0 45.8 44.6 5.4 0.2 14.8 13.0 0.4 27.2 33.7 10.5 12.9 6.5 28.0 3.2 0.4 7.0 10.6 11.6 21.6 0.1 0.2 1.3 0.1 0.3 0.1 0.6 0.2 0.2 0.3 0.9 0.5 0.3 2.3 0.1 0.6 0.9 0.2 0.1 36.2 45.4 172.8 57.5 66.1 13.5 18.0 18.1 24.7 19.0 18.9 29.8 18.5 9.6 18.5 37.2 16.2 11.2 3.3 5.0 8.0 6.1 32.6 6.1 22.2 8.6 10.0 18.4 12.5 1.5 8.2 10.5 0.0 4.5 3.8 18.2 3.3 15.3 19.3 0.0 51.8 5.1 2.0 3.8 10.7 11.0 6.3 5.1 12.8 44.3 6.1 6.7 19.8 16.1 18.3 25.4 26.7 5.0 2.1 16.1 3.6 15.0 13.9 52.1 2.1 21.6 20.8 8.5 7.9 4.9 2.2 5.2 6.6 12.0 17.4 27.6 13.1 10.9 6.2 9.8 7.7 8.7 19.7 1.0 7.2 1.7 14.8 4.2 ZBTB8A "BOZF1, FLJ90065, ZBTB8, ZNF916A" ENSG00000160062 "Zinc finger and BTB domain containing 8A" Q96BR9 1 32539427-32605941 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 1.5" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031768, HPA031769, HPA031770" Approved Approved "Nuclear speckles,Focal adhesion sites" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 36: Stromal cells - Cell proliferation" "Nuclear speckles, Focal adhesion sites" "HPA031768: AB_10610568, HPA031769: AB_2674036, HPA031770: AB_2674037" "unprognostic (1.71e-1)" "unprognostic (1.98e-1)" "unprognostic (1.01e-1)" "unprognostic (7.40e-2)" "unprognostic (7.21e-2)" "unprognostic (2.85e-2)" "unprognostic (9.45e-5)" "unprognostic (1.62e-2)" "unprognostic (2.04e-1)" "unprognostic (7.83e-3)" "unprognostic (4.23e-3)" "unprognostic (1.78e-1)" "unprognostic (8.10e-2)" "unprognostic (2.88e-2)" "unprognostic (1.61e-1)" "unprognostic (1.47e-1)" "unprognostic (3.15e-2)" 3.8 2.2 1.5 1.6 1.6 1.2 3.4 3.5 1.6 6.2 1.1 2.9 1.8 6.1 3.2 3.4 3.3 2.7 2.4 1.3 0.9 2.4 2.0 2.8 0.9 1.5 1.2 3.4 2.6 3.6 1.8 2.7 1.5 3.0 3.0 1.5 2.5 4.0 2.8 1.8 2.0 5.1 0.8 1.3 3.1 2.4 1.2 1.3 5.5 6.1 1.5 3.7 3.0 2.5 6.4 1.8 7.2 7.8 5.0 6.7 5.4 6.2 4.9 5.7 5.8 0.8 5.0 5.3 4.2 6.7 2.5 4.9 7.2 5.0 5.0 1.4 4.8 0.2 5.7 2.7 6.5 1.2 0.3 4.5 7.0 4.2 11.0 5.7 6.5 4.5 1.0 3.6 5.8 6.5 3.5 0.6 6.5 3.1 2.5 6.3 10.4 4.1 3.5 6.4 6.0 5.5 8.8 4.3 8.4 3.8 5.7 2.9 6.8 7.6 6.2 10.5 4.6 6.5 3.3 3.9 5.2 1.3 3.2 1.5 0.2 0.2 0.2 0.1 0.2 0.2 0.1 0.2 0.2 0.3 0.1 0.2 1.0 0.7 0.2 0.5 0.1 0.1 1.5 1.6 3.5 1.6 1.3 0.9 1.5 1.2 1.5 0.8 1.2 2.5 17.0 16.0 13.8 5.9 1.4 4.1 7.8 8.0 5.2 11.7 7.4 5.8 4.1 4.3 5.8 7.3 22.9 3.5 3.8 6.5 1.9 6.9 5.9 7.5 30.0 20.1 4.9 6.1 9.4 5.1 6.7 14.5 9.7 11.8 2.5 11.2 30.4 5.2 1.6 6.7 7.8 5.4 2.0 4.1 7.4 7.2 19.9 2.3 3.6 15.9 1.8 4.0 0.0 21.6 20.6 6.0 4.7 35.3 3.2 10.7 3.3 3.0 3.6 10.8 32.9 23.3 12.9 2.0 6.4 3.8 3.8 1.5 2.3 4.1 8.8 6.4 ZC2HC1C "C14orf140, FAM164C" ENSG00000119703 "Zinc finger C2HC-type containing 1C" Q53FD0 14 75064109-75119502 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 23.9;testis: 55.3" "Group enriched" "Detected in many" 5 "Early spermatids: 165.2;Late spermatids: 195.1;Spermatocytes: 198.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "CAPAN-2: 6.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA050928, HPA065062" Enhanced Approved "Nuclear speckles,Mitochondria" No No "Cluster 22: NK-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" Mitochondria "HPA050928: AB_2681277, HPA065062: AB_2732728" "unprognostic (8.01e-2)" "unprognostic (2.01e-2)" "unprognostic (9.61e-2)" "unprognostic (8.01e-2)" "unprognostic (1.97e-3)" "unprognostic (6.00e-2)" "unprognostic (8.94e-2)" "unprognostic (1.20e-2)" "unprognostic (3.71e-3)" "unprognostic (3.22e-2)" "unprognostic (1.09e-3)" "unprognostic (2.26e-1)" "prognostic favorable (4.63e-13)" "unprognostic (4.69e-3)" "unprognostic (7.37e-2)" "unprognostic (3.12e-1)" "unprognostic (1.81e-1)" 1.1 2.5 2.5 0.6 2.7 0.4 1.7 2.8 2.9 1.8 5.1 2.7 3.1 1.3 23.9 1.3 11.0 1.6 5.2 2.4 2.9 5.5 8.4 2.5 0.2 3.1 3.7 0.6 5.1 6.9 6.1 0.8 2.9 1.3 2.4 2.6 2.9 3.4 4.7 1.6 2.4 1.0 2.8 0.8 1.6 55.3 2.9 2.3 7.0 1.5 0.5 1.4 0.6 3.3 3.8 2.8 0.3 3.3 0.2 0.0 1.8 0.3 1.1 1.4 0.8 4.8 6.9 3.3 2.6 0.4 2.6 1.0 0.0 0.0 1.2 3.9 0.3 0.6 1.0 2.3 2.5 0.0 1.8 0.3 0.4 1.6 0.0 1.7 1.1 0.2 5.8 1.0 0.7 0.6 0.4 0.3 0.7 2.4 1.8 0.0 0.2 0.7 4.3 0.3 5.7 1.3 2.4 2.0 1.5 0.6 2.9 0.9 0.7 0.9 0.9 1.0 0.8 4.0 4.9 1.1 1.4 0.4 0.6 0.3 0.0 0.2 0.6 0.0 0.1 0.4 0.3 0.1 0.1 0.2 0.1 0.1 0.1 1.2 0.1 0.2 0.9 0.1 2.5 2.7 2.8 2.9 2.4 2.9 3.1 3.7 2.9 2.8 2.9 3.3 0.8 6.4 9.7 2.0 0.9 1.8 1.9 1.3 4.6 4.5 7.9 5.1 7.0 2.8 6.6 11.0 10.4 2.3 1.6 2.5 3.9 4.6 165.2 21.0 2.1 2.0 5.3 0.4 2.4 1.4 1.1 2.5 1.1 1.9 1.3 1.1 2.9 4.7 1.7 11.8 2.1 2.3 0.0 1.0 0.7 195.1 3.1 1.0 3.6 1.0 0.9 3.0 8.2 0.5 1.0 1.6 0.6 2.6 0.6 2.8 4.2 7.4 32.5 8.5 6.6 5.2 2.0 198.5 5.5 1.9 0.9 5.1 0.9 2.3 3.9 1.3 ZC3H11A "KIAA0663, ZC3HDC11A" ENSG00000058673 "Zinc finger CCCH-type containing 11A" O75152 1 203795623-203854999 "Predicted intracellular proteins" "mRNA transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA026439, HPA028490, HPA028526" Approved Approved "Nuclear speckles" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 59: Non-specific - Transcription" "Nuclear speckles" "HPA026439: AB_10599829, HPA028490: AB_10601447, HPA028526: AB_10611533" "unprognostic (8.69e-2)" "unprognostic (1.25e-2)" "unprognostic (3.45e-2)" "unprognostic (3.35e-1)" "unprognostic (1.51e-1)" "unprognostic (3.67e-2)" "unprognostic (2.87e-2)" "unprognostic (2.44e-1)" "unprognostic (1.81e-2)" "unprognostic (2.38e-1)" "unprognostic (1.13e-1)" "unprognostic (4.71e-2)" "prognostic unfavorable (5.58e-4)" "unprognostic (2.55e-1)" "unprognostic (1.82e-1)" "unprognostic (1.07e-2)" "unprognostic (1.41e-1)" 14.9 15.6 8.3 20.9 12.3 28.8 15.5 11.5 11.7 14.2 13.1 14.7 20.4 18.7 12.8 16.8 16.1 15.2 13.9 8.2 9.6 16.6 16.2 14.5 26.2 9.4 8.9 18.9 15.5 19.8 5.6 17.4 10.0 16.2 17.7 20.2 19.4 13.2 23.4 26.2 22.5 16.6 5.6 23.1 20.4 22.9 9.7 33.4 22.6 23.1 25.5 16.1 6.5 15.5 29.7 23.8 45.2 28.8 28.7 22.9 49.7 33.6 24.0 27.0 30.2 32.7 36.2 37.6 19.9 35.7 22.0 41.0 35.8 19.7 37.2 56.6 25.8 36.3 39.3 16.5 15.4 50.9 62.3 19.1 23.5 29.0 28.2 34.2 25.5 40.4 74.0 51.6 24.0 24.2 56.2 20.3 42.6 20.8 19.4 40.1 52.1 24.7 19.1 50.0 33.1 31.4 33.8 27.5 29.8 51.7 29.5 38.1 39.2 39.2 34.7 33.1 32.3 36.8 37.3 58.5 25.2 29.1 30.7 15.6 3.6 5.5 5.2 3.5 7.2 5.0 4.7 4.8 4.2 3.5 5.9 4.4 7.9 5.1 5.8 2.3 5.0 4.2 8.3 12.3 11.5 11.7 8.2 9.6 9.4 8.9 10.0 5.6 9.7 15.5 2.4 12.8 22.5 105.8 49.2 101.5 61.7 50.6 112.7 46.2 1.1 0.9 54.2 58.6 38.4 0.0 45.9 31.1 18.2 43.6 0.0 0.3 54.7 3.1 2.9 49.9 46.7 67.1 71.9 0.2 27.3 51.5 53.0 3.9 25.3 0.9 54.7 70.0 32.5 84.1 69.0 64.2 28.5 54.6 60.8 14.3 60.3 37.2 48.0 82.4 31.7 40.5 41.2 103.0 169.4 0.6 42.2 67.4 64.1 104.0 52.1 0.3 43.9 49.8 78.9 83.3 42.1 63.6 40.2 84.5 111.5 51.0 41.4 0.5 52.1 114.2 ZC3H11B ZC3HDC11B ENSG00000215817 "Zinc finger CCCH-type containing 11B" A0A1B0GTU1 1 219608010-219613145 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "testis: 5.1" "Cell type enhanced" "Detected in some" "Breast glandular cells: 1.3;Cardiomyocytes: 1.5;Collecting duct cells: 1.8;monocytes: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA026439, HPA028490, HPA028526" Uncertain Approved "Nuclear speckles" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 7: Non-specific - Mitochondria" "Nuclear speckles" "HPA026439: AB_10599829, HPA028490: AB_10601447, HPA028526: AB_10611533" "unprognostic (1.75e-1)" "unprognostic (5.54e-2)" "unprognostic (2.21e-1)" "unprognostic (2.82e-1)" "unprognostic (3.42e-1)" "unprognostic (1.92e-1)" "unprognostic (5.07e-1)" "unprognostic (1.15e-1)" "unprognostic (1.02e-1)" "unprognostic (2.44e-1)" "unprognostic (1.30e-1)" "unprognostic (8.19e-2)" "unprognostic (2.28e-2)" "unprognostic (7.87e-2)" "unprognostic (9.15e-2)" "unprognostic (2.56e-2)" "unprognostic (1.87e-2)" 0.2 0.2 0.0 0.2 0.0 0.2 0.2 0.0 0.0 0.2 0.0 0.2 0.1 0.2 0.2 0.2 0.2 0.1 0.3 0.0 0.0 0.2 0.2 0.2 0.1 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.2 0.0 0.2 0.2 0.0 0.3 0.4 0.2 0.1 0.0 0.2 0.2 5.1 0.0 0.0 0.2 0.0 0.1 0.1 0.2 0.0 0.1 0.1 0.4 0.3 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.3 0.0 0.1 0.3 0.2 0.2 0.0 0.1 0.1 0.2 0.1 0.0 0.2 0.2 0.2 0.1 0.3 0.2 0.1 0.3 0.6 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.2 0.5 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.3 0.3 1.5 0.0 0.0 1.8 0.0 0.0 0.8 0.0 0.0 0.3 0.0 0.6 0.8 0.3 0.0 0.0 0.0 0.7 0.0 0.5 0.0 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 ZC3H14 "FLJ11806, NY-REN-37, UKp68" ENSG00000100722 "Zinc finger CCCH-type containing 14" Q6PJT7 14 88562970-88627596 "Disease related genes, Human disease related genes, Predicted intracellular proteins" RNA-binding "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "testis: 173.6" "Cell type enhanced" "Detected in all" "Early spermatids: 1282.6;Late spermatids: 460.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049798, HPA053510" Enhanced Enhanced "Nucleoli,Nucleoli rim,Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 77: Retina - Visual perception" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Nuclear speckles" "Nucleoli, Nucleoli rim" "HPA049798: AB_2680888, HPA053510: AB_2682174" "unprognostic (5.80e-3)" "unprognostic (2.25e-1)" "unprognostic (1.35e-2)" "unprognostic (7.39e-2)" "unprognostic (2.06e-1)" "unprognostic (1.91e-1)" "unprognostic (6.47e-3)" "unprognostic (9.57e-2)" "unprognostic (7.21e-3)" "unprognostic (2.77e-3)" "unprognostic (4.83e-2)" "unprognostic (1.50e-2)" "prognostic favorable (7.08e-4)" "unprognostic (2.09e-1)" "unprognostic (8.23e-2)" "unprognostic (3.71e-1)" "unprognostic (4.25e-2)" 20.9 21.0 9.5 16.3 10.7 23.6 22.5 26.9 14.9 23.7 38.3 26.9 19.7 25.7 25.1 20.2 27.7 18.7 24.7 10.8 8.1 24.3 43.3 24.2 18.2 5.5 5.1 26.1 37.4 33.2 24.3 23.0 6.8 23.6 31.2 41.1 31.4 23.6 30.2 21.4 21.2 28.2 4.4 15.7 21.6 173.6 9.0 20.0 32.2 25.1 23.6 22.1 19.5 13.1 39.5 75.4 64.7 54.8 50.8 48.6 68.3 58.6 54.2 85.2 74.7 55.3 63.2 55.1 41.9 61.4 46.3 44.4 46.8 55.7 115.9 43.4 34.7 26.7 51.6 42.5 51.2 57.3 34.3 39.2 65.2 68.2 66.9 53.3 56.7 47.2 54.2 21.0 75.8 86.3 52.8 28.1 39.9 60.8 64.1 46.1 83.9 23.1 54.3 68.2 45.6 37.0 75.2 75.4 37.3 54.3 75.3 36.3 39.2 101.3 65.1 43.1 59.2 29.3 30.0 61.7 49.0 27.1 48.0 19.1 20.7 29.4 18.9 25.3 20.4 16.8 18.0 20.8 22.1 15.4 17.2 16.9 3.8 25.9 29.6 12.5 17.2 17.4 9.5 10.7 26.9 14.9 10.8 8.1 5.5 5.1 6.8 4.4 9.0 13.1 25.2 121.8 57.0 38.2 18.1 22.7 24.5 25.2 21.1 61.2 27.0 24.9 22.6 28.6 37.6 20.2 77.2 49.2 25.4 28.4 35.2 25.6 1282.6 53.0 46.6 28.7 31.8 17.1 88.8 23.0 27.4 30.5 20.9 34.3 45.6 51.8 24.3 38.1 20.3 65.6 65.5 31.4 34.6 14.9 16.3 460.1 39.4 19.6 5.4 34.7 20.0 33.6 18.6 64.3 62.9 22.0 16.4 47.4 18.6 26.0 27.4 32.4 53.0 78.9 13.1 46.6 35.4 217.9 81.5 23.0 19.7 40.6 20.1 39.2 32.8 16.3 ZC3H18 NHN1 ENSG00000158545 "Zinc finger CCCH-type containing 18" Q86VM9 16 88570403-88631964 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040847, HPA041327" Enhanced Enhanced "Nuclear speckles" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "HPA040847: AB_10794865, HPA041327: AB_10795005" "unprognostic (3.05e-2)" "unprognostic (1.38e-1)" "unprognostic (2.88e-1)" "unprognostic (2.90e-1)" "unprognostic (1.92e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (4.06e-4)" "unprognostic (1.10e-2)" "unprognostic (7.37e-2)" "unprognostic (2.89e-2)" "unprognostic (2.79e-1)" "unprognostic (2.07e-3)" "prognostic favorable (3.68e-4)" "unprognostic (5.83e-2)" "unprognostic (1.40e-1)" "unprognostic (4.29e-2)" "unprognostic (4.01e-1)" 14.1 11.0 10.7 18.7 11.3 25.5 13.6 14.4 14.2 14.3 5.7 16.1 14.9 17.4 4.3 14.5 14.2 8.8 14.3 10.6 11.4 10.9 12.0 13.1 18.4 10.1 9.6 14.1 13.7 12.3 10.1 11.9 9.2 11.5 8.1 9.0 13.6 8.2 22.8 15.3 15.6 10.1 7.5 17.4 14.5 25.3 10.2 19.1 13.1 10.1 12.3 15.3 13.7 12.1 45.3 59.6 42.6 42.8 20.7 17.7 68.3 44.5 24.1 40.8 18.5 58.8 38.3 55.1 36.9 21.1 27.3 53.0 40.3 33.7 25.6 32.5 51.2 36.6 29.2 50.6 26.2 28.5 30.7 16.1 25.2 43.3 20.8 16.9 25.5 37.8 101.4 17.8 20.4 87.4 91.6 50.5 66.7 35.3 35.5 111.0 29.3 40.4 18.5 28.3 44.9 38.7 85.2 23.5 25.2 24.8 53.3 38.1 35.1 43.6 45.2 32.0 45.5 39.5 67.2 130.8 38.6 65.7 47.0 2.3 2.0 2.0 2.5 2.3 2.8 2.3 2.4 2.7 1.9 1.9 2.1 1.7 3.4 3.1 5.4 2.8 3.3 2.1 10.7 11.3 14.4 14.2 10.6 11.4 10.1 9.6 9.2 7.5 10.2 12.1 24.9 28.9 24.2 11.1 29.6 16.8 17.0 11.1 13.1 26.6 13.8 14.4 10.2 20.0 23.9 16.5 35.5 24.1 45.6 30.1 7.9 16.5 76.2 21.9 28.7 21.3 25.0 28.6 12.0 16.6 22.1 18.7 22.4 32.1 20.8 26.6 16.4 12.9 18.2 28.6 11.9 18.5 10.2 20.1 21.1 10.0 21.8 30.5 14.2 12.2 23.9 18.1 46.4 7.1 15.7 17.5 21.7 17.0 35.5 20.5 20.3 8.4 13.1 44.0 6.6 28.8 19.5 41.4 37.5 19.6 22.3 25.2 39.2 25.1 24.7 16.6 ZCCHC4 "FLJ23024, HSPC052, ZGRF4" ENSG00000168228 "Zinc finger CCHC-type containing 4" Q9H5U6 4 25312774-25370383 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 19.6;Oligodendrocytes: 23.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035575, HPA035576" Uncertain Approved "Nuclear speckles,Golgi apparatus" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 59: Non-specific - Transcription" "Nuclear speckles, Golgi apparatus" "HPA035575: AB_2674682, HPA035576: AB_10671516" "unprognostic (5.52e-1)" "unprognostic (1.54e-1)" "unprognostic (2.94e-2)" "unprognostic (3.06e-2)" "unprognostic (1.87e-2)" "unprognostic (5.84e-2)" "unprognostic (2.80e-3)" "unprognostic (1.71e-1)" "unprognostic (3.00e-1)" "unprognostic (1.51e-1)" "unprognostic (1.23e-1)" "unprognostic (1.73e-1)" "unprognostic (1.85e-2)" "unprognostic (1.05e-1)" "unprognostic (1.55e-1)" "unprognostic (3.59e-2)" "unprognostic (1.07e-2)" 4.5 3.6 2.8 3.5 3.6 3.8 5.0 3.7 3.5 4.3 3.5 3.9 3.8 5.2 4.0 3.3 4.3 3.3 4.6 2.7 3.0 3.8 3.5 3.6 5.2 3.3 3.1 6.1 3.4 6.0 2.7 3.3 3.4 3.9 4.0 4.8 3.9 3.9 7.4 4.3 4.0 3.7 3.0 4.4 3.4 4.4 3.3 4.8 4.5 5.5 4.5 4.1 3.6 4.3 4.5 2.8 9.1 4.2 6.9 8.8 8.1 11.4 12.1 13.1 15.0 4.4 11.9 7.5 3.1 7.0 12.9 3.5 8.9 8.3 18.2 1.8 4.8 7.0 5.8 7.4 8.8 11.6 4.9 7.0 9.2 12.5 9.8 7.8 6.3 11.4 12.7 3.6 11.3 3.4 12.0 15.2 12.5 7.4 6.0 8.0 13.9 4.6 7.1 4.7 8.4 5.8 4.9 4.1 7.4 8.8 6.0 6.9 5.0 11.0 4.6 7.2 15.7 7.2 9.6 11.0 11.8 11.0 10.8 1.4 1.9 0.6 3.0 2.4 4.4 3.5 3.9 3.8 2.8 3.6 3.7 4.1 1.1 4.4 2.3 2.1 4.3 2.3 2.8 3.6 3.7 3.5 2.7 3.0 3.3 3.1 3.4 3.0 3.3 4.3 5.9 0.0 5.8 12.1 7.6 3.7 4.0 4.3 6.8 3.7 3.0 2.9 6.4 1.5 5.5 0.0 2.1 5.9 4.2 2.1 3.9 3.8 1.5 5.5 5.1 4.6 2.4 2.1 10.7 2.3 4.5 4.8 3.1 3.9 1.3 6.4 2.2 3.1 5.1 3.3 15.5 3.6 6.1 4.4 2.2 0.5 4.1 3.3 3.6 5.6 2.6 5.5 5.2 19.6 23.6 2.9 3.9 5.3 3.7 2.7 5.7 4.5 8.2 5.2 0.0 5.2 5.7 9.0 9.1 4.9 3.4 3.7 5.4 4.0 4.4 2.5 ZCWPW2 ZCW2 ENSG00000206559 "Zinc finger CW-type and PWWP domain containing 2" Q504Y3 3 28348721-28538122 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 9.9" "Cell type enhanced" "Detected in many" "Astrocytes: 35.6;Early spermatids: 95.0;Excitatory neurons: 33.7;Inhibitory neurons: 34.9;Oligodendrocyte precursor cells: 32.2;Oligodendrocytes: 31.7;Spermatocytes: 68.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035035, HPA039839" Uncertain Approved "Nuclear speckles" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" "HPA035035: AB_10602256, HPA039839: AB_2676708" "unprognostic (1.11e-1)" "unprognostic (4.18e-2)" "unprognostic (1.97e-1)" "unprognostic (1.34e-1)" "unprognostic (2.41e-1)" "unprognostic (4.59e-3)" "unprognostic (6.53e-2)" "unprognostic (6.09e-4)" "unprognostic (3.21e-1)" "unprognostic (2.70e-2)" "unprognostic (1.73e-3)" "unprognostic (1.12e-1)" "unprognostic (1.10e-4)" "unprognostic (1.06e-2)" "unprognostic (7.88e-2)" "unprognostic (1.40e-2)" "unprognostic (2.38e-2)" 1.5 1.7 1.8 0.9 1.5 0.8 1.8 1.6 1.9 1.4 0.2 1.4 1.2 2.1 2.1 1.3 1.0 2.0 2.7 1.7 1.1 1.6 1.2 1.3 1.2 0.8 1.0 2.4 1.9 1.5 1.2 1.2 1.0 2.2 1.1 1.6 2.3 1.1 6.2 1.9 0.9 1.0 0.8 1.1 1.8 9.9 1.2 0.6 2.5 4.5 1.0 0.8 0.8 1.6 0.3 0.2 0.8 0.3 1.2 2.8 1.2 1.1 0.8 0.3 0.3 0.2 0.9 0.7 0.5 0.6 0.8 0.4 0.2 0.2 0.3 0.4 0.4 0.3 1.1 0.3 0.6 0.5 0.6 1.2 0.5 0.3 0.5 1.3 0.5 1.5 0.3 1.0 1.5 0.3 0.2 0.6 0.3 0.1 1.1 0.3 0.3 0.6 1.2 0.1 0.3 0.9 0.2 0.4 0.7 0.8 0.4 2.6 1.0 0.8 0.4 0.7 0.6 0.3 0.2 0.3 2.8 0.5 1.0 1.0 0.7 1.1 0.3 0.7 0.2 0.1 0.3 0.2 0.3 0.2 0.5 0.7 1.0 0.2 0.2 0.4 0.3 0.2 1.8 1.5 1.6 1.9 1.7 1.1 0.8 1.0 1.0 0.8 1.2 1.6 1.6 0.0 2.0 35.6 0.4 0.6 2.7 3.7 1.2 3.0 1.6 2.7 13.6 0.0 4.3 0.0 0.0 2.4 0.1 0.4 5.9 0.5 95.0 1.2 1.2 1.0 1.2 0.0 33.7 0.9 1.4 4.3 0.0 0.6 2.5 0.8 1.4 0.5 1.3 3.3 34.9 1.9 8.2 0.6 0.7 17.7 4.7 1.3 0.0 13.1 0.7 3.7 1.0 32.2 31.7 0.6 0.3 4.9 0.3 1.1 0.6 2.6 1.7 2.0 0.0 4.4 4.5 68.7 5.8 1.1 1.6 1.2 0.6 1.3 0.7 1.3 ZDHHC15 "DHHC15, FLJ31812, MRX91" ENSG00000102383 "Zinc finger DHHC-type palmitoyltransferase 15" Q96MV8 X 75368427-75523502 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Acyltransferase, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 18.2;Inhibitory neurons: 17.7;Oligodendrocyte precursor cells: 17.1" "Cancer enhanced" "Detected in some" "glioma: 2.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 3.2;K-562: 2.1;LHCN-M2: 2.2;MOLT-4: 2.4;NTERA-2: 2.0;RH-30: 3.1;RPTEC TERT1: 1.7;SH-SY5Y: 2.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003618, HPA064901" Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear speckles" Cytosol "HPA003618: AB_2217686, HPA064901: " "unprognostic (8.28e-2)" "unprognostic (1.73e-1)" "unprognostic (8.05e-2)" "unprognostic (1.62e-5)" "unprognostic (1.64e-2)" "unprognostic (1.00e-1)" "unprognostic (4.00e-4)" "unprognostic (1.96e-2)" "unprognostic (3.19e-1)" "unprognostic (8.70e-2)" "unprognostic (3.77e-3)" "unprognostic (1.40e-1)" "unprognostic (4.78e-13)" "unprognostic (2.60e-3)" "unprognostic (1.17e-2)" "unprognostic (1.09e-1)" "unprognostic (9.67e-4)" 0.8 1.5 1.7 0.3 1.7 0.1 1.6 1.8 1.5 1.6 1.3 1.0 0.2 1.9 1.0 0.8 1.2 0.8 1.7 1.5 2.5 1.5 0.2 1.2 0.3 2.2 2.2 2.5 1.1 1.1 1.1 0.0 2.0 1.1 0.5 1.9 4.5 1.1 0.3 0.7 0.3 1.5 1.8 0.8 0.4 0.6 3.0 0.8 2.0 0.5 0.2 0.7 0.8 2.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 2.1 0.0 2.2 0.0 2.4 0.0 2.0 0.0 0.0 0.0 3.1 0.0 1.7 0.0 0.8 2.6 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.5 0.0 0.4 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.7 1.8 1.5 1.5 2.5 2.2 2.2 2.0 1.8 3.0 2.0 2.9 6.4 3.1 8.5 0.1 4.0 1.6 0.0 3.4 4.2 2.0 1.5 9.5 1.5 1.3 5.5 4.2 0.0 0.3 0.0 0.0 0.7 0.0 0.2 2.9 3.5 1.8 0.4 18.2 0.7 0.0 3.5 0.0 0.3 1.3 2.5 2.2 0.1 0.1 0.0 17.7 0.0 0.0 0.0 4.4 0.2 0.9 0.1 0.0 5.6 0.0 2.2 1.0 17.1 9.1 0.2 0.0 3.8 0.0 0.7 0.0 1.0 0.0 2.3 6.6 5.4 2.5 0.2 0.7 2.2 3.7 0.0 0.5 2.3 0.0 0.6 ZFP14 "KIAA1559, ZNF531" ENSG00000142065 "ZFP14 zinc finger protein" Q9HCL3 19 36334453-36379201 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 63.2;Rod photoreceptor cells: 105.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030637 Uncertain Approved "Nuclear speckles" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 21: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "HPA030637: AB_10602353" "unprognostic (1.89e-1)" "unprognostic (3.80e-2)" "unprognostic (9.61e-2)" "unprognostic (3.53e-1)" "unprognostic (2.20e-2)" "unprognostic (3.04e-3)" "unprognostic (3.17e-2)" "unprognostic (2.23e-2)" "unprognostic (1.96e-2)" "unprognostic (1.17e-1)" "unprognostic (3.18e-3)" "unprognostic (1.91e-1)" "unprognostic (5.51e-2)" "unprognostic (1.86e-1)" "unprognostic (7.23e-2)" "unprognostic (1.20e-1)" "prognostic favorable (2.75e-5)" 1.8 2.6 4.0 2.5 5.2 1.1 4.1 6.2 4.7 2.9 6.9 2.3 2.8 3.3 5.2 1.6 3.1 1.9 1.7 3.8 5.4 3.2 2.0 1.9 3.7 4.3 4.5 4.2 1.9 4.7 3.8 2.1 4.7 3.0 2.0 9.0 2.2 3.0 1.5 3.2 2.5 2.2 3.7 3.6 2.5 1.1 4.4 3.9 4.4 1.5 3.5 2.4 2.4 8.6 1.5 2.5 5.1 4.7 4.3 2.1 1.2 0.7 2.2 1.4 2.2 1.7 1.2 4.2 1.8 1.0 1.1 0.5 2.1 0.3 1.5 1.6 1.6 3.7 2.5 1.4 1.4 3.0 3.8 0.9 0.9 0.6 0.1 2.6 1.9 4.8 1.1 0.0 2.2 1.0 4.8 1.2 3.8 2.2 1.1 3.8 2.9 1.2 1.5 2.9 2.8 4.2 2.6 0.8 1.5 2.6 1.6 2.4 1.3 1.4 3.2 1.5 0.7 1.1 1.9 2.1 0.2 0.4 2.5 5.6 2.8 4.1 4.1 3.4 4.4 8.1 4.7 5.6 2.8 6.0 6.5 6.6 1.7 4.5 2.9 4.2 4.8 1.3 4.0 5.2 6.2 4.7 3.8 5.4 4.3 4.5 4.7 3.7 4.4 8.6 12.0 0.0 5.3 17.9 25.5 3.2 6.7 4.5 8.0 63.2 8.5 6.1 6.5 20.0 5.9 12.9 52.1 8.2 18.5 8.2 7.9 8.9 2.8 6.5 7.9 11.2 13.2 10.3 32.9 4.5 2.4 9.3 7.7 4.6 13.3 22.1 12.5 4.3 8.6 47.1 39.5 8.3 6.1 8.5 4.6 0.8 15.5 8.8 3.6 17.8 15.6 16.9 44.3 41.2 56.2 4.9 13.0 19.5 4.9 7.0 13.9 12.4 11.3 105.3 32.9 10.4 9.1 7.9 8.3 3.0 2.6 2.5 17.3 15.2 7.7 7.2 ZIM2 ZNF656 ENSG00000269699 "Zinc finger imprinted 2" Q9NZV7 19 56774547-56840729 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.6;ovary: 7.2;testis: 3.7" "Cell type enhanced" "Detected in many" "Early spermatids: 25.0;Inhibitory neurons: 19.2;Late spermatids: 33.7;Spermatocytes: 11.7;Spermatogonia: 19.3;Theca cells: 15.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.1;Hep G2: 2.5" HPA071856 Approved "Nuclear speckles,Cytosol" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nuclear speckles" Cytosol "HPA071856: AB_2686460" "unprognostic (9.01e-4)" "unprognostic (8.77e-2)" "unprognostic (5.09e-2)" "unprognostic (4.60e-2)" "unprognostic (2.45e-2)" "unprognostic (3.01e-1)" "unprognostic (2.33e-1)" "unprognostic (8.68e-3)" "unprognostic (4.12e-1)" "unprognostic (1.00e-1)" 0.1 2.3 1.8 0.0 1.2 0.0 0.4 0.9 3.5 0.3 3.2 0.3 0.0 0.4 0.0 0.1 0.6 0.0 0.3 1.1 3.6 0.1 0.1 0.0 0.0 0.8 0.7 7.2 0.1 0.1 0.9 2.0 0.2 0.0 0.0 0.9 0.2 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.1 3.7 1.7 0.0 0.2 0.0 0.1 0.2 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.2 0.9 3.5 1.1 3.6 0.8 0.7 0.2 0.8 1.7 1.8 0.1 0.0 0.0 5.5 0.0 0.1 0.1 0.0 0.6 7.0 0.4 0.9 0.9 0.0 0.0 0.0 0.0 5.5 0.0 0.0 1.9 0.1 25.0 0.0 1.2 0.3 0.0 0.0 8.8 0.0 1.2 1.8 0.0 0.1 0.0 7.6 0.0 0.0 0.7 10.1 19.2 0.0 0.0 0.0 0.3 33.7 1.8 0.0 0.0 1.0 0.0 3.8 0.0 6.6 5.7 0.0 0.0 1.5 0.0 0.1 0.0 0.1 0.0 2.4 0.0 1.5 1.0 11.7 19.3 0.3 0.1 9.9 0.0 15.5 0.0 0.0 ZKSCAN7 "FLJ12738, ZNF167, ZNF448, ZNF64, ZSCAN39" ENSG00000196345 "Zinc finger with KRAB and SCAN domains 7" Q9P0L1 3 44555193-44594173 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 15.4;Late spermatids: 17.1;Oligodendrocyte precursor cells: 10.6;Spermatocytes: 10.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 4.0;NTERA-2: 3.1;SH-SY5Y: 4.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048312, HPA049906, HPA071850" Uncertain Supported "Nuclear speckles,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "Nuclear speckles" "HPA048312: AB_2680352, HPA049906: AB_2680946, HPA071850: AB_2686458" "unprognostic (3.31e-2)" "unprognostic (4.49e-2)" "unprognostic (7.25e-2)" "unprognostic (5.78e-3)" "unprognostic (3.41e-2)" "unprognostic (1.21e-3)" "unprognostic (2.18e-1)" "unprognostic (2.31e-2)" "unprognostic (3.45e-2)" "unprognostic (1.06e-1)" "unprognostic (4.22e-4)" "unprognostic (5.91e-2)" "unprognostic (1.18e-3)" "unprognostic (2.83e-2)" "unprognostic (2.28e-1)" "unprognostic (1.54e-1)" "unprognostic (7.17e-3)" 1.5 2.7 0.8 1.0 0.8 0.3 1.6 1.8 1.0 2.8 1.2 1.9 0.4 2.8 2.3 0.8 2.5 0.9 2.1 0.7 0.8 2.7 2.2 1.3 1.3 0.7 0.7 4.2 3.0 0.8 4.2 0.7 0.6 2.4 0.7 3.0 1.6 1.3 1.0 0.6 1.7 1.4 0.4 2.0 1.7 4.1 0.7 2.2 2.6 0.6 1.2 2.4 1.5 0.9 0.0 0.0 2.6 4.0 0.8 0.3 0.0 1.3 1.1 1.4 1.5 0.0 0.0 0.0 0.4 0.9 0.4 0.0 0.0 0.8 1.7 0.0 0.0 0.1 0.9 1.1 2.4 0.0 0.0 1.8 0.9 0.7 0.0 0.0 0.4 0.0 0.0 0.0 2.1 0.0 0.0 0.0 3.1 0.0 0.0 0.0 1.2 0.0 0.7 0.3 1.9 4.8 0.0 0.1 0.0 2.9 0.0 1.9 0.4 0.8 0.3 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.5 0.2 0.3 0.8 0.1 0.2 0.3 0.5 0.6 0.2 0.7 0.3 0.7 0.4 0.6 0.3 0.6 0.5 0.3 0.8 0.8 1.8 1.0 0.7 0.8 0.7 0.7 0.6 0.4 0.7 0.9 0.3 0.0 0.5 5.2 1.4 0.1 0.4 0.9 0.6 6.6 0.9 1.1 4.8 0.0 0.4 1.8 0.0 0.0 3.3 0.2 0.0 2.1 15.4 0.6 1.8 0.9 3.0 1.3 4.3 0.5 0.1 2.1 0.0 0.4 0.0 3.1 0.4 1.4 1.1 3.3 4.7 0.3 0.0 0.3 0.4 17.1 0.9 0.7 0.0 1.0 1.4 3.8 6.2 10.6 6.4 0.9 0.0 2.6 0.4 0.5 0.4 1.3 0.3 4.2 0.0 1.0 1.1 10.8 3.6 0.5 0.4 0.1 1.0 2.9 0.6 0.2 ZMYND15 DKFZp434N127 ENSG00000141497 "Zinc finger MYND-type containing 15" Q9H091 17 4739833-4746119 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 28.3" "Cell type enriched" "Detected in many" 6 "Early spermatids: 191.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 2.1;CAPAN-2: 1.9;HaCaT: 1.6;T-47d: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA023286 Uncertain "Nuclear speckles,Cytosol" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nuclear speckles" Cytosol "HPA023286: AB_1859076" "unprognostic (2.30e-3)" "unprognostic (1.63e-2)" "unprognostic (1.61e-2)" "unprognostic (7.49e-3)" "unprognostic (3.62e-2)" "unprognostic (7.86e-2)" "unprognostic (4.97e-2)" "unprognostic (1.59e-2)" "unprognostic (1.33e-2)" "unprognostic (3.49e-1)" "unprognostic (6.72e-3)" "unprognostic (4.02e-1)" "unprognostic (5.47e-2)" "unprognostic (4.62e-2)" "unprognostic (9.24e-3)" "unprognostic (2.69e-1)" "unprognostic (2.07e-1)" 1.8 1.3 1.6 2.4 1.6 1.0 1.7 1.6 2.5 0.9 1.7 0.8 4.0 0.6 0.5 0.9 1.1 2.8 0.6 1.6 1.8 1.9 3.1 4.6 1.7 2.4 2.0 0.7 1.2 5.5 1.4 1.2 2.0 1.7 0.7 0.3 3.1 0.8 0.4 1.4 3.0 0.7 2.0 5.5 1.9 28.3 2.4 0.8 1.1 0.1 0.4 1.8 0.7 2.6 2.1 0.3 0.0 0.9 0.0 0.1 0.1 0.0 0.5 0.5 1.1 0.9 1.9 0.0 0.0 0.0 0.2 1.6 0.4 0.1 0.0 0.2 0.7 0.0 0.2 0.5 0.3 0.0 0.6 0.1 0.2 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.7 0.2 0.2 0.0 0.0 0.6 0.6 0.9 0.0 1.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 1.6 1.6 1.6 2.5 1.6 1.8 2.4 2.0 2.0 2.0 2.4 2.6 0.8 0.0 2.0 1.3 0.6 0.9 8.0 1.8 0.6 0.3 4.4 3.7 0.7 2.8 3.1 1.8 0.0 0.1 0.2 3.3 0.0 1.6 191.4 2.8 0.3 1.4 1.2 0.0 0.0 3.9 0.0 0.7 4.6 2.7 0.0 0.3 3.9 0.6 5.2 0.0 0.1 2.9 0.0 11.9 7.3 30.9 0.6 12.9 1.8 1.9 21.9 2.0 0.0 1.0 0.5 3.5 1.4 2.2 0.1 6.7 3.8 0.8 3.7 0.3 0.0 0.2 1.0 24.3 2.0 0.5 0.9 0.0 0.2 0.3 1.3 8.5 ZNF160 "F11, FLJ00032, HKr18, HZF5, KIAA1611, KR18" ENSG00000170949 "Zinc finger protein 160" Q9HCG1 19 53066606-53103436 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 67.7;Theca cells: 66.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RT4: 48.6" HPA023599 Uncertain Approved "Nuclear speckles,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 1: Thyroid gland - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" Cytosol "HPA023599: AB_2218442" "unprognostic (1.18e-2)" "unprognostic (4.75e-2)" "unprognostic (1.16e-2)" "unprognostic (9.46e-2)" "unprognostic (4.90e-2)" "unprognostic (8.31e-3)" "unprognostic (2.65e-5)" "unprognostic (5.20e-2)" "unprognostic (4.11e-3)" "unprognostic (2.03e-1)" "unprognostic (3.12e-2)" "unprognostic (6.03e-3)" "unprognostic (2.71e-3)" "unprognostic (2.87e-1)" "unprognostic (4.63e-1)" "unprognostic (1.71e-1)" "prognostic favorable (2.67e-5)" 19.3 29.0 7.3 7.8 10.2 7.4 17.6 12.2 11.6 19.6 4.9 17.4 8.0 18.9 13.7 11.0 17.9 13.9 15.9 6.9 11.9 22.5 13.8 15.0 11.6 9.0 9.5 20.8 12.7 18.1 10.2 13.7 10.3 15.3 10.7 14.2 14.2 13.5 8.4 12.4 12.5 14.1 6.7 33.3 13.7 14.9 9.6 13.5 29.3 9.0 10.4 17.2 15.5 17.1 9.8 8.6 11.6 17.8 19.1 13.4 19.7 10.4 13.9 8.3 13.2 7.4 6.0 11.1 8.8 9.7 11.0 7.0 11.1 10.7 16.4 8.3 13.4 17.2 6.6 4.2 10.5 0.0 11.3 16.7 10.8 8.9 12.5 20.9 9.0 12.9 8.8 0.0 15.8 6.7 14.5 10.6 10.9 2.6 13.7 9.1 12.2 8.6 13.0 48.6 9.8 12.8 0.0 8.2 1.6 37.0 8.8 10.0 17.3 23.0 8.2 6.9 7.7 6.1 27.4 15.9 4.0 4.2 11.1 10.9 3.1 11.4 6.7 4.2 10.0 8.6 6.9 9.2 4.4 9.9 10.4 8.3 6.6 17.6 6.6 4.2 7.9 5.5 7.3 10.2 12.2 11.6 6.9 11.9 9.0 9.5 10.3 6.7 9.6 17.1 46.5 22.4 30.5 23.8 18.5 4.0 10.0 14.7 9.6 23.2 9.4 9.5 20.6 15.7 14.1 9.2 29.2 8.3 16.8 8.0 5.9 8.2 31.0 12.4 21.6 29.8 8.4 9.9 17.1 6.8 9.5 15.4 20.4 16.0 18.3 67.7 34.2 5.0 6.4 47.1 18.8 8.3 8.2 11.3 6.4 10.2 10.8 13.0 1.8 15.9 7.1 13.8 19.6 21.6 29.4 8.1 6.3 14.3 12.7 12.6 11.1 5.9 12.7 19.1 13.1 13.9 18.4 8.3 8.3 8.1 4.0 10.4 18.5 66.0 5.7 13.0 ZNF165 "CT53, ZSCAN7" ENSG00000197279 "Zinc finger protein 165" P49910 6 28080568-28089563 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 17.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 94.6;Early spermatids: 152.7;Glandular and luminal cells: 75.8;Paneth cells: 120.3;Syncytiotrophoblasts: 79.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 14.4;BEWO: 22.9;GAMG: 16.9" "Low region specificity" "Detected in all" HPA007247 Approved "Nuclear speckles,Microtubules" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear speckles, Microtubules" "HPA007247: AB_2797217" "unprognostic (1.85e-1)" "unprognostic (2.01e-3)" "unprognostic (1.12e-2)" "unprognostic (2.43e-3)" "unprognostic (1.45e-1)" "unprognostic (4.32e-3)" "unprognostic (3.42e-1)" "unprognostic (2.09e-1)" "unprognostic (1.93e-2)" "prognostic favorable (2.10e-4)" "unprognostic (1.18e-3)" "unprognostic (1.29e-2)" "prognostic favorable (1.19e-5)" "unprognostic (1.10e-1)" "unprognostic (2.40e-1)" "unprognostic (2.18e-1)" "prognostic favorable (9.82e-5)" 0.4 0.8 0.4 1.0 0.5 1.4 2.1 0.6 0.8 1.4 2.1 2.4 2.2 1.1 5.1 2.2 1.8 0.9 0.5 0.5 0.5 4.5 2.4 1.9 1.3 0.9 0.7 0.7 4.6 4.8 3.8 3.1 1.0 1.0 3.3 1.7 2.0 1.2 0.7 1.0 1.8 0.5 0.4 0.9 2.5 17.2 0.4 0.5 2.9 0.1 1.7 2.5 1.1 0.7 14.4 0.9 0.8 1.1 0.3 0.5 22.9 0.5 0.5 0.9 0.8 9.0 10.3 1.2 3.9 0.2 16.9 5.4 2.0 6.2 0.6 0.4 3.6 0.7 1.5 9.7 0.3 2.3 2.0 0.3 3.2 0.7 8.8 0.6 0.3 0.8 2.3 1.1 0.5 3.9 0.6 2.7 1.9 12.2 1.4 1.9 0.8 7.7 4.7 6.5 9.6 0.7 1.2 11.1 1.3 2.5 5.5 0.5 0.4 0.8 1.1 0.4 1.0 3.4 9.6 3.6 0.5 2.6 0.4 5.8 1.7 3.4 1.3 1.4 1.6 7.0 1.5 1.0 1.8 8.6 2.5 2.0 2.5 1.4 1.7 5.5 0.7 0.9 0.4 0.5 0.6 0.8 0.5 0.5 0.9 0.7 1.0 0.4 0.4 0.7 0.8 6.4 7.0 0.0 23.2 8.5 16.5 2.3 2.8 0.8 24.5 9.4 0.4 4.3 5.0 3.7 0.0 9.4 4.2 94.6 3.9 18.2 152.7 55.4 5.9 1.3 53.9 0.0 1.2 12.3 9.0 0.6 13.7 75.8 0.0 0.6 0.0 0.4 1.5 0.0 0.9 53.7 6.1 0.6 3.2 19.5 0.9 2.8 5.4 0.0 1.6 1.5 0.0 0.0 0.1 17.5 120.3 2.2 12.4 6.5 9.0 2.0 12.0 2.6 0.0 0.6 1.5 33.6 4.4 8.5 11.8 79.6 8.5 0.3 34.9 40.8 ZNF169 MGC51961 ENSG00000175787 "Zinc finger protein 169" Q14929 9 94259298-94301829 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 18.4;Inhibitory neurons: 16.7;NK-cells: 15.5;Oligodendrocyte precursor cells: 14.1;Oligodendrocytes: 19.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041769, HPA061185" Uncertain Approved "Nucleoplasm,Nuclear speckles,Vesicles,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 51: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nuclear speckles" "Vesicles, Cytosol" "HPA041769: AB_2677662, HPA061185: " "unprognostic (1.07e-1)" "unprognostic (2.29e-1)" "unprognostic (1.03e-1)" "unprognostic (3.39e-1)" "unprognostic (3.27e-2)" "unprognostic (9.08e-3)" "unprognostic (1.18e-3)" "unprognostic (7.33e-2)" "unprognostic (2.27e-1)" "unprognostic (7.45e-2)" "unprognostic (6.79e-2)" "unprognostic (1.69e-2)" "unprognostic (1.49e-4)" "unprognostic (6.32e-2)" "unprognostic (1.15e-1)" "unprognostic (1.69e-1)" "unprognostic (2.15e-4)" 3.0 2.7 3.8 4.4 4.4 3.2 3.9 4.3 4.8 5.4 3.4 4.3 2.9 3.9 4.2 2.6 4.8 1.7 2.6 3.8 2.4 3.7 2.1 3.2 6.0 3.7 2.6 5.4 3.3 2.3 2.7 2.1 3.8 4.2 5.5 4.2 3.9 2.6 4.6 5.2 5.7 2.8 1.8 6.1 4.1 2.6 3.5 3.8 4.8 1.8 5.1 4.0 4.1 5.7 3.0 2.6 2.8 4.9 1.5 3.4 3.1 1.1 2.0 2.2 2.3 1.8 4.3 7.3 1.4 1.7 2.2 5.8 5.7 2.7 2.9 4.0 6.3 5.1 6.5 3.3 1.8 7.8 5.0 3.0 2.9 1.8 2.8 2.8 2.7 6.8 4.6 2.1 2.8 2.9 3.7 4.4 4.6 6.2 3.2 3.1 2.0 2.3 1.9 2.5 2.9 3.5 1.9 3.5 1.4 2.7 2.2 3.2 3.1 2.0 2.6 2.6 2.2 3.9 1.5 1.4 1.9 5.2 1.9 2.2 3.0 3.2 2.4 3.4 3.1 3.0 2.9 1.7 2.1 4.0 3.0 4.1 2.5 3.3 2.6 2.0 3.1 1.7 3.8 4.4 4.3 4.8 3.8 2.4 3.7 2.6 3.8 1.8 3.5 5.7 2.0 3.2 0.5 10.4 8.0 0.3 2.2 1.3 1.2 4.8 1.0 1.3 1.2 1.5 2.6 1.8 4.2 0.5 3.9 2.5 0.0 1.1 1.0 0.6 1.4 2.3 1.2 3.8 18.4 0.9 0.8 1.8 2.6 0.5 0.0 6.3 2.5 0.8 0.7 5.0 16.7 4.1 0.0 4.4 1.6 1.0 5.9 4.1 0.0 7.5 7.8 2.3 15.5 14.1 19.9 1.2 3.1 3.4 2.6 2.6 4.3 1.0 2.4 4.5 0.0 2.9 1.7 5.2 3.6 0.7 0.4 0.4 4.7 3.7 2.1 2.4 ZNF217 ZABC1 ENSG00000171940 "Zinc finger protein 217" O75362 20 53567071-53609907 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 129.1;Glandular and luminal cells: 154.8;Squamous epithelial cells: 118.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 148.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051857 Approved Enhanced "Nuclear speckles" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 44: Endometrium - Transcription" "Nuclear speckles" "HPA051857: AB_2681641" "unprognostic (4.17e-2)" "unprognostic (4.05e-1)" "unprognostic (2.41e-1)" "unprognostic (1.18e-1)" "unprognostic (1.44e-1)" "unprognostic (3.72e-2)" "unprognostic (2.49e-3)" "unprognostic (1.19e-1)" "unprognostic (1.47e-2)" "unprognostic (7.17e-2)" "unprognostic (4.13e-3)" "unprognostic (2.87e-2)" "unprognostic (2.03e-1)" "unprognostic (2.33e-1)" "unprognostic (2.90e-1)" "unprognostic (2.67e-1)" "unprognostic (2.52e-2)" 15.0 4.2 4.0 20.5 3.8 31.1 22.0 4.0 3.8 17.9 9.6 18.1 12.8 11.8 8.3 13.1 11.1 15.1 5.4 3.2 3.9 11.0 14.5 12.2 29.6 6.0 6.0 9.7 10.1 17.3 4.8 19.0 5.4 16.5 17.5 0.8 18.9 8.2 3.4 16.9 13.5 8.9 4.7 29.2 17.9 22.1 5.9 26.0 10.9 6.4 23.7 21.8 11.6 5.0 28.7 33.4 27.5 40.3 25.1 28.5 60.1 31.3 31.8 34.8 17.1 21.5 31.2 27.5 32.9 38.4 44.9 27.5 22.3 33.0 40.1 19.9 6.3 8.9 14.3 37.8 19.5 14.5 36.7 15.6 31.1 18.6 51.4 27.4 20.1 28.2 19.8 126.9 26.4 113.8 50.1 31.9 29.2 16.2 32.8 38.9 23.0 32.3 20.3 62.8 2.8 7.6 29.2 148.2 30.5 34.6 44.3 60.3 14.2 69.7 25.6 36.0 38.9 52.4 62.4 23.0 25.4 16.0 22.8 9.1 6.1 10.9 3.2 7.4 4.1 5.6 3.4 4.1 4.9 4.3 3.8 3.8 23.3 6.8 15.8 5.0 3.6 3.1 4.0 3.8 4.0 3.8 3.2 3.9 6.0 6.0 5.4 4.7 5.9 5.0 18.7 0.0 8.0 7.5 30.6 129.1 40.3 25.3 71.7 0.6 41.7 22.5 8.2 20.0 26.1 18.4 0.0 16.4 43.7 58.5 9.8 27.5 39.1 76.2 34.4 21.6 6.0 24.4 0.5 16.7 17.7 21.7 42.8 154.8 12.0 24.8 14.6 26.8 16.1 0.0 0.5 32.0 22.4 43.6 52.3 25.9 6.8 39.6 21.4 22.5 43.0 1.8 20.6 3.0 3.4 22.2 39.8 5.3 31.7 65.8 13.8 11.0 30.4 0.5 0.0 13.3 22.7 8.0 23.3 118.8 106.8 45.1 40.5 12.3 24.7 87.1 ZNF250 "MGC9718, ZFP647, ZNF647" ENSG00000196150 "Zinc finger protein 250" P15622 8 144876497-144902168 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020853 Uncertain Approved "Nuclear speckles,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "Nuclear speckles" Cytosol "HPA020853: AB_1859152" "unprognostic (1.16e-3)" "unprognostic (9.56e-2)" "unprognostic (2.63e-1)" "unprognostic (2.60e-3)" "unprognostic (1.03e-1)" "unprognostic (5.95e-3)" "unprognostic (3.73e-3)" "unprognostic (2.72e-2)" "unprognostic (6.27e-2)" "unprognostic (7.37e-2)" "unprognostic (4.94e-2)" "unprognostic (1.06e-1)" "prognostic favorable (2.43e-7)" "unprognostic (2.23e-1)" "unprognostic (6.79e-2)" "unprognostic (5.82e-2)" "prognostic favorable (8.26e-4)" 4.7 3.9 3.2 3.3 3.2 2.9 5.6 10.5 4.7 9.7 2.3 6.9 4.8 7.4 2.8 6.4 7.6 3.3 4.9 2.4 4.5 7.6 4.0 5.1 3.0 3.0 3.2 9.7 4.9 6.0 7.3 5.5 3.3 7.5 3.6 7.9 6.0 5.2 4.8 10.9 5.2 4.2 1.5 5.5 4.9 4.5 3.3 4.5 10.0 5.8 3.3 6.3 8.6 3.4 5.1 2.9 13.4 11.1 6.8 5.9 4.3 5.6 6.4 9.4 7.7 2.4 3.9 12.0 9.8 6.5 3.8 6.6 5.3 4.8 6.0 3.8 7.8 10.8 14.9 3.5 2.0 1.8 3.6 3.9 6.5 5.6 4.5 7.2 3.9 7.1 8.6 11.5 7.9 6.8 12.6 4.1 4.0 6.0 12.5 14.4 5.9 5.0 7.8 3.7 13.2 10.1 11.8 4.4 5.3 5.3 6.3 6.1 5.1 9.2 8.8 7.3 5.3 5.6 5.1 8.0 4.7 6.2 4.1 3.2 5.1 5.8 10.5 2.7 8.1 10.3 7.7 5.8 6.6 9.7 8.9 7.3 2.9 6.0 3.7 2.6 11.7 4.5 3.2 3.2 10.5 4.7 2.4 4.5 3.0 3.2 3.3 1.5 3.3 3.4 5.8 12.8 3.0 10.7 10.7 5.5 3.2 7.5 10.2 8.4 4.3 6.6 4.3 1.5 3.9 5.5 0.0 2.3 18.6 2.4 3.9 7.5 7.4 5.1 6.0 5.5 4.2 1.7 11.9 1.9 1.3 5.2 2.6 4.9 2.5 6.3 5.0 2.1 1.7 8.4 17.5 1.9 12.2 2.2 8.0 3.0 4.1 3.0 5.4 4.7 2.0 3.3 5.2 11.1 7.8 2.6 1.0 5.3 8.2 3.3 3.7 3.4 5.0 9.9 13.1 4.1 6.1 14.3 8.7 4.4 5.5 1.9 10.9 4.9 3.4 2.3 ZNF304 ENSG00000131845 "Zinc finger protein 304" Q9HCX3 19 57351271-57359898 "Predicted intracellular proteins, Transcription factors" "Angiogenesis, Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA050531 Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 35: Glandular cells - Unknown function" "Nuclear speckles" Cytosol "HPA050531: AB_2681160" "unprognostic (4.44e-1)" "unprognostic (1.73e-3)" "unprognostic (5.63e-2)" "unprognostic (1.50e-1)" "unprognostic (1.07e-1)" "unprognostic (9.72e-2)" "unprognostic (2.86e-1)" "unprognostic (1.60e-1)" "prognostic unfavorable (4.95e-4)" "unprognostic (1.54e-1)" "unprognostic (1.28e-3)" "unprognostic (5.97e-2)" "prognostic favorable (1.52e-7)" "unprognostic (1.01e-1)" "unprognostic (4.33e-2)" "unprognostic (4.31e-1)" "unprognostic (9.00e-3)" 4.4 6.3 4.2 3.5 4.4 4.3 6.5 6.7 6.0 4.3 3.5 4.9 2.6 5.0 7.4 5.2 5.2 4.3 6.2 4.8 4.4 4.5 3.5 5.3 5.2 3.0 3.6 6.7 2.5 10.0 5.0 5.5 3.2 5.5 3.1 5.3 4.7 6.2 5.0 6.1 3.8 5.1 3.4 6.8 3.9 4.4 4.3 7.5 7.0 5.3 7.3 4.2 3.0 4.1 6.4 3.1 7.6 9.6 6.2 5.9 4.8 6.4 9.7 7.1 16.0 0.0 3.0 5.3 3.9 7.4 3.7 2.3 4.4 8.4 10.6 1.7 20.5 8.4 8.9 4.5 4.4 4.7 5.1 7.1 11.0 7.0 9.7 7.6 4.5 11.8 2.6 0.0 7.6 1.7 10.0 2.7 5.1 0.0 9.9 6.3 12.3 6.7 5.0 13.7 6.0 6.4 6.7 5.1 4.4 6.9 6.2 6.6 5.2 9.9 5.9 3.1 6.8 8.1 7.7 7.8 6.3 0.1 5.3 2.5 1.3 1.1 1.4 1.0 2.6 2.3 2.4 2.0 1.8 1.8 1.9 2.1 0.1 2.8 2.8 0.9 2.0 1.7 4.2 4.4 6.7 6.0 4.8 4.4 3.0 3.6 3.2 3.4 4.3 4.1 5.0 0.0 0.5 4.2 3.2 6.4 0.8 1.3 4.6 4.9 6.9 5.1 4.4 7.2 4.6 0.0 0.0 1.7 2.9 1.0 1.9 1.7 1.2 3.2 1.8 4.1 0.0 0.0 8.2 1.0 0.8 1.9 1.5 4.0 0.0 5.2 10.4 2.7 1.6 3.3 6.4 1.4 4.1 2.1 2.8 1.1 1.8 1.6 3.6 2.8 0.6 1.4 1.0 3.0 2.8 0.9 0.5 2.2 1.6 1.4 0.8 1.6 6.2 2.2 0.0 2.2 2.8 2.2 4.2 5.4 5.5 1.1 2.1 5.0 1.9 1.2 ZNF337 dJ694B14.1 ENSG00000130684 "Zinc finger protein 337" Q9Y3M9 20 25673195-25696853 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 26.4;Excitatory neurons: 30.4;Inhibitory neurons: 26.8;Oligodendrocyte precursor cells: 26.2;Oligodendrocytes: 29.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA044303, HPA064219" Approved Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "Nuclear speckles" "HPA044303: AB_2678890, HPA064219: AB_2685215" "unprognostic (2.14e-1)" "unprognostic (2.19e-2)" "unprognostic (1.65e-2)" "unprognostic (1.80e-1)" "unprognostic (1.30e-1)" "unprognostic (5.81e-3)" "unprognostic (4.54e-3)" "unprognostic (6.99e-2)" "unprognostic (2.34e-1)" "unprognostic (1.34e-2)" "unprognostic (3.15e-2)" "unprognostic (9.36e-4)" "prognostic unfavorable (2.87e-6)" "unprognostic (1.29e-1)" "unprognostic (1.54e-1)" "unprognostic (3.93e-2)" "unprognostic (8.82e-3)" 15.8 13.4 21.5 7.4 21.9 10.3 16.1 28.6 25.5 27.4 23.0 26.5 5.9 21.5 16.1 14.8 26.2 6.9 14.4 20.9 20.6 19.2 11.6 16.6 11.2 20.6 20.3 31.2 13.1 10.4 24.4 7.7 20.5 27.4 8.9 25.9 12.7 13.2 12.5 13.1 18.6 11.7 19.2 21.7 14.0 9.3 20.6 15.3 18.8 8.6 9.5 22.4 19.7 25.3 10.0 17.3 14.0 9.9 11.2 14.3 11.9 8.4 7.3 6.3 7.8 3.6 9.1 12.3 7.8 7.8 12.8 16.0 9.3 27.9 8.7 4.4 7.2 7.5 13.9 15.8 9.6 6.9 8.1 13.3 24.1 7.5 22.1 16.7 10.0 15.7 6.8 10.6 12.5 11.4 18.6 13.4 3.7 5.3 12.2 11.8 12.8 6.0 6.6 11.1 11.2 12.0 8.3 13.4 11.1 17.2 7.7 9.4 13.5 14.1 7.2 9.4 11.3 14.9 8.3 4.3 6.7 5.9 11.2 0.0 1.6 3.2 4.6 2.7 5.0 2.3 3.7 4.2 2.7 1.8 5.2 6.1 0.0 3.9 1.5 2.5 2.5 2.6 21.5 21.9 28.6 25.5 20.9 20.6 20.6 20.3 20.5 19.2 20.6 25.3 8.6 6.4 15.4 26.4 4.3 2.0 5.6 3.4 4.6 8.4 4.1 5.2 1.2 2.8 10.8 3.7 2.1 3.8 4.5 1.2 3.9 4.3 1.4 6.7 8.9 5.6 5.4 1.3 30.4 3.1 2.0 5.4 2.0 4.4 5.1 9.8 3.3 3.2 3.3 6.7 26.8 4.2 0.0 3.1 1.1 0.3 7.2 4.3 1.8 25.3 3.1 7.9 11.3 26.2 29.3 2.7 1.0 5.7 1.7 5.4 1.6 1.9 15.5 13.0 0.0 6.3 4.8 8.1 10.2 3.6 2.4 2.3 6.2 5.4 2.6 1.9 ZNF382 "FLJ14686, KS1" ENSG00000161298 "Zinc finger protein 382" Q96SR6 19 36604817-36634114 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.1;retina: 18.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 23.8;Early spermatids: 23.3;Excitatory neurons: 19.1;Horizontal cells: 50.5;Late spermatids: 20.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 11.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049259 Approved Approved "Nuclear speckles" NA NA "Cluster 37: B-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 44: HDLM-2 - Immune response" "Cluster 62: Horizontal cells - Visual perception" "Nuclear speckles" "HPA049259: AB_2680694" "unprognostic (5.43e-3)" "unprognostic (5.16e-2)" "unprognostic (1.17e-1)" "unprognostic (2.68e-3)" "unprognostic (6.13e-2)" "unprognostic (1.85e-3)" "unprognostic (5.63e-2)" "unprognostic (6.64e-2)" "unprognostic (1.12e-2)" "unprognostic (5.76e-2)" "unprognostic (4.43e-3)" "unprognostic (3.07e-3)" "unprognostic (1.76e-5)" "unprognostic (8.71e-2)" "unprognostic (2.06e-2)" "unprognostic (2.53e-1)" "unprognostic (6.22e-2)" 1.7 2.8 2.6 1.9 4.2 0.9 1.6 12.1 4.3 1.9 0.1 2.8 0.6 2.3 2.0 1.5 2.7 1.4 4.0 3.7 1.9 1.8 0.7 1.3 2.7 0.2 0.2 2.1 1.3 2.2 5.4 2.3 0.0 1.7 0.8 18.0 1.5 1.4 0.9 0.6 1.6 2.1 0.0 2.9 1.1 3.8 4.3 3.2 2.8 2.6 3.2 1.8 1.0 3.9 0.2 0.1 4.5 6.4 1.8 2.5 1.5 2.0 0.6 5.9 6.0 0.1 0.3 4.0 4.2 2.5 2.5 0.1 5.8 0.1 3.7 11.3 2.6 6.6 0.3 1.6 5.0 0.9 7.6 3.4 0.2 3.3 0.1 5.9 0.7 7.8 0.1 0.2 3.9 0.6 9.3 2.1 2.9 0.0 2.2 0.4 1.9 1.8 1.6 0.1 0.5 8.6 0.3 0.3 3.7 6.5 2.7 0.7 0.1 1.4 0.3 0.3 5.9 9.9 0.8 0.4 0.0 0.1 3.5 2.4 0.5 3.3 5.2 0.6 7.7 9.0 7.7 5.4 2.1 5.3 6.3 7.3 0.9 4.4 0.6 2.2 4.9 2.6 2.6 4.2 12.1 4.3 3.7 1.9 0.2 0.2 0.0 0.0 4.3 3.9 2.4 3.2 0.0 7.5 3.5 0.1 0.9 0.5 2.2 23.8 1.7 2.0 13.2 1.5 1.0 3.7 10.4 2.0 1.3 0.1 5.9 3.2 23.3 3.5 2.3 2.4 0.0 4.8 19.1 0.4 1.0 1.7 0.5 1.9 0.0 6.8 2.5 0.3 2.9 50.5 16.0 0.1 0.0 0.8 0.8 20.5 0.6 1.2 1.8 1.9 0.7 4.3 0.0 8.0 8.5 0.2 0.3 1.2 0.3 0.4 0.0 1.8 2.6 13.7 0.0 2.6 2.7 6.5 3.0 0.5 0.0 0.1 3.5 2.9 0.0 0.3 ZNF441 FLJ38637 ENSG00000197044 "Zinc finger protein 441" Q8N8Z8 19 11767000-11784078 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 19.0;Sertoli cells: 19.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" HPA063338 Approved "Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 1: Thyroid gland - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nuclear speckles" "HPA063338: AB_2684989" "unprognostic (1.97e-1)" "unprognostic (1.96e-1)" "unprognostic (2.51e-1)" "unprognostic (1.04e-1)" "unprognostic (1.18e-1)" "unprognostic (6.42e-4)" "unprognostic (2.60e-2)" "unprognostic (1.92e-3)" "unprognostic (1.17e-1)" "unprognostic (3.91e-2)" "unprognostic (2.37e-3)" "unprognostic (1.30e-2)" "unprognostic (1.33e-3)" "unprognostic (1.80e-1)" "unprognostic (1.75e-1)" "unprognostic (1.68e-2)" "unprognostic (2.70e-3)" 3.3 2.9 3.4 3.0 3.9 0.9 5.9 6.9 4.0 3.6 2.3 3.4 2.3 4.6 6.1 1.7 3.9 2.1 3.8 3.6 3.3 6.4 4.4 3.5 4.9 2.7 3.1 6.4 3.4 7.2 7.1 3.2 3.0 4.5 3.2 7.1 3.8 4.9 3.6 3.1 4.2 3.2 3.1 4.6 3.2 2.7 3.0 3.6 7.1 2.7 4.4 3.9 2.5 3.9 2.1 0.0 2.5 2.1 3.0 3.2 2.7 5.0 2.8 3.7 3.6 2.3 0.7 4.4 2.6 3.2 1.8 1.5 1.6 3.0 4.2 0.0 1.8 2.0 1.7 3.7 2.7 0.0 3.6 3.9 3.3 2.6 2.0 2.5 2.1 1.8 3.3 0.0 5.8 0.0 4.7 1.3 0.4 0.9 3.6 1.7 5.0 1.3 3.0 3.4 1.9 3.0 3.3 1.0 1.8 2.4 3.3 4.5 1.0 8.0 1.9 7.0 3.4 4.4 6.9 1.9 0.4 0.0 3.2 0.0 0.3 0.8 1.0 0.3 0.7 1.4 1.1 1.5 0.6 1.6 1.4 1.6 0.5 0.9 1.6 0.4 0.8 0.6 3.4 3.9 6.9 4.0 3.6 3.3 2.7 3.1 3.0 3.1 3.0 3.9 5.6 16.0 8.7 8.5 9.5 0.4 0.8 1.2 0.6 11.7 2.7 2.3 14.5 0.0 4.5 11.0 14.6 2.1 5.1 1.9 3.9 1.7 0.2 2.5 3.8 5.3 0.0 1.7 12.3 1.2 0.6 3.6 1.1 1.8 2.5 6.4 3.6 1.9 0.8 6.7 9.5 1.6 2.0 0.8 1.2 0.8 2.5 2.2 3.6 2.8 1.8 7.0 8.2 4.0 4.2 1.1 1.5 7.2 1.9 0.9 1.5 3.0 0.9 19.0 19.7 6.7 6.2 7.6 6.0 1.4 0.0 0.8 3.4 4.9 0.8 0.4 ZNF446 "FLJ20626, ZKSCAN20, ZSCAN52" ENSG00000083838 "Zinc finger protein 446" Q9NWS9 19 58474017-58481230 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 40.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 27.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052786, HPA078262" Uncertain Approved "Nuclear speckles" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nuclear speckles" "HPA052786: , HPA078262: " "unprognostic (1.52e-2)" "unprognostic (8.71e-3)" "unprognostic (2.72e-1)" "unprognostic (5.04e-3)" "unprognostic (3.28e-2)" "unprognostic (1.78e-2)" "unprognostic (5.15e-3)" "unprognostic (1.12e-1)" "unprognostic (3.18e-1)" "unprognostic (3.94e-1)" "prognostic favorable (1.32e-4)" "unprognostic (3.94e-1)" "unprognostic (9.24e-2)" "unprognostic (2.43e-1)" "unprognostic (9.96e-2)" "unprognostic (1.82e-1)" "unprognostic (1.91e-3)" 6.0 7.2 8.0 3.4 7.7 3.0 6.8 9.4 8.5 9.7 7.2 8.7 3.3 9.4 4.6 5.9 9.9 3.2 6.6 7.8 8.0 9.4 10.8 4.8 4.0 8.5 7.9 11.5 9.3 7.7 12.5 2.3 7.5 10.9 2.2 3.7 6.2 5.5 6.4 9.1 6.5 3.3 7.2 6.6 7.9 13.2 7.6 4.9 9.5 3.1 2.5 8.7 6.5 8.6 4.4 8.8 6.0 6.2 5.8 10.1 5.6 2.6 7.9 2.4 2.8 4.3 4.1 4.0 3.8 3.8 10.2 6.4 2.6 3.5 0.9 5.9 27.7 4.8 6.7 3.9 8.6 2.6 6.9 9.4 6.3 4.0 4.0 8.7 5.2 7.0 2.9 2.8 3.5 5.2 7.0 3.0 2.2 4.1 5.5 6.1 4.2 5.5 4.8 8.0 7.4 6.8 4.9 7.3 4.5 3.3 5.3 3.6 3.7 11.4 3.8 2.4 5.7 9.6 13.2 2.6 5.7 1.4 4.9 2.9 2.1 2.3 2.8 3.1 1.8 2.3 3.3 1.8 3.0 2.8 2.2 2.9 2.6 1.7 5.2 1.9 2.8 1.9 8.0 7.7 9.4 8.5 7.8 8.0 8.5 7.9 7.5 7.2 7.6 8.6 4.8 3.2 3.2 7.8 4.6 2.0 2.3 7.0 4.0 8.9 7.3 8.3 1.0 14.3 5.6 5.5 8.4 5.6 2.2 8.3 3.9 7.9 5.5 14.4 5.7 4.2 10.7 5.7 7.8 5.1 3.8 4.5 6.1 5.8 8.2 6.7 2.2 3.1 4.5 8.4 9.7 6.6 10.2 3.3 2.3 5.2 7.2 2.4 3.6 3.7 2.1 10.8 7.2 5.5 9.5 4.9 4.8 5.3 3.4 1.9 6.8 6.3 11.8 8.5 0.0 6.8 4.8 40.0 21.1 4.1 3.7 3.4 3.4 8.8 5.3 1.5 ZNF527 KIAA1829 ENSG00000189164 "Zinc finger protein 527" Q8NB42 19 37371061-37393066 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA037740, HPA037741" Uncertain Approved "Nuclear speckles,Golgi apparatus" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "Golgi apparatus" "HPA037740: AB_10672284, HPA037741: AB_2675642" "unprognostic (4.36e-2)" "unprognostic (5.10e-2)" "unprognostic (1.68e-2)" "unprognostic (1.09e-3)" "unprognostic (1.84e-2)" "unprognostic (1.30e-2)" "unprognostic (9.26e-2)" "unprognostic (8.70e-3)" "unprognostic (6.47e-3)" "unprognostic (1.91e-1)" "unprognostic (6.05e-4)" "unprognostic (8.34e-3)" "unprognostic (8.92e-2)" "unprognostic (6.83e-2)" "unprognostic (1.44e-2)" "unprognostic (1.52e-3)" "unprognostic (3.17e-4)" 2.0 2.1 1.9 1.3 1.8 2.5 2.0 2.1 2.4 2.8 1.6 2.5 0.8 2.2 1.7 1.5 2.2 1.3 2.3 1.7 2.1 2.2 1.7 1.5 2.1 1.9 1.6 3.3 1.7 2.7 2.3 1.2 2.0 2.3 1.5 3.2 1.9 1.7 2.3 1.7 1.7 1.9 1.5 1.9 1.7 2.4 1.9 2.5 2.5 3.0 1.5 2.3 2.3 2.3 2.3 2.3 2.1 2.8 1.6 3.3 0.8 2.2 2.2 1.9 2.6 2.1 0.6 2.1 2.6 2.1 1.4 0.9 3.1 1.9 2.5 4.9 1.4 1.7 2.8 0.2 2.3 4.1 2.5 2.6 2.7 2.1 3.6 2.3 2.0 3.4 0.9 1.5 2.4 0.8 2.7 2.2 1.6 2.6 1.0 3.4 2.6 1.7 1.7 2.3 4.1 1.8 3.4 1.0 1.5 1.8 2.3 3.6 3.6 2.0 2.7 2.5 2.4 4.0 5.4 6.4 0.1 3.1 1.7 2.2 1.0 3.4 3.3 1.4 2.9 3.5 2.1 3.0 1.3 2.8 3.0 3.7 1.0 2.4 0.9 1.5 2.3 2.3 1.9 1.8 2.1 2.4 1.7 2.1 1.9 1.6 2.0 1.5 1.9 2.3 2.6 9.6 4.8 5.2 2.5 2.7 1.9 3.3 3.4 6.1 2.4 1.8 8.7 1.5 3.5 0.0 12.5 2.3 5.8 1.2 3.9 1.9 1.3 2.0 2.9 3.0 1.2 2.5 5.8 1.5 1.3 3.5 1.1 2.4 1.3 4.5 2.2 1.9 1.7 6.7 6.9 1.9 4.1 0.8 1.3 0.8 2.5 2.0 0.0 2.8 1.7 3.8 6.2 6.6 7.0 0.5 0.6 1.5 1.8 1.9 1.4 2.4 4.0 10.2 0.0 4.1 3.7 5.3 2.7 2.0 1.6 2.1 4.6 3.3 1.9 1.3 ZNF528 KIAA1827 ENSG00000167555 "Zinc finger protein 528" Q3MIS6 19 52397849-52418412 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RT4: 51.2;U-266/84: 69.0" HPA065435 Approved "Nuclear speckles,Cytosol" No No "Cluster 15: NK-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" Cytosol "HPA065435: " "unprognostic (1.90e-2)" "unprognostic (1.69e-1)" "unprognostic (1.59e-1)" "unprognostic (3.73e-1)" "unprognostic (1.30e-1)" "unprognostic (2.28e-2)" "unprognostic (1.61e-1)" "unprognostic (9.60e-2)" "unprognostic (4.81e-3)" "unprognostic (1.26e-2)" "unprognostic (2.45e-1)" "unprognostic (1.42e-2)" "unprognostic (2.98e-3)" "unprognostic (3.26e-3)" "unprognostic (2.78e-2)" "unprognostic (1.24e-1)" "unprognostic (8.60e-3)" 8.9 9.2 7.9 5.4 10.1 5.7 10.9 16.8 8.6 9.9 9.6 8.6 4.9 13.5 18.8 8.9 13.6 10.1 10.1 6.6 10.3 9.6 4.7 8.0 9.1 9.2 7.6 18.2 5.2 12.7 9.2 9.9 11.2 11.6 8.8 19.7 10.7 9.3 6.4 11.4 6.7 8.3 4.0 11.3 9.3 13.1 9.8 9.8 17.7 5.7 10.7 9.8 8.5 13.6 0.2 0.0 6.1 36.5 13.6 16.9 15.0 13.6 22.3 8.2 18.1 0.2 6.9 0.3 3.3 16.9 20.4 4.1 0.0 8.6 10.5 0.1 9.8 5.7 2.0 3.5 20.4 0.1 15.2 17.2 15.5 9.0 0.0 2.5 19.7 0.3 3.8 0.6 11.9 0.2 21.5 2.9 15.9 0.3 9.4 0.2 24.5 6.5 10.1 51.2 25.1 20.8 0.0 1.1 9.1 21.2 24.2 3.3 23.3 14.2 16.3 5.6 18.8 0.6 69.0 12.9 7.1 0.2 22.5 7.6 5.1 11.8 6.6 5.4 12.7 7.8 8.2 10.2 5.4 11.1 7.7 6.9 1.4 17.6 5.5 8.8 9.6 3.9 7.9 10.1 16.8 8.6 6.6 10.3 9.2 7.6 11.2 4.0 9.8 13.6 9.8 6.4 3.2 8.8 5.8 3.7 4.1 5.2 1.2 19.6 8.6 7.1 12.2 2.8 7.4 1.8 14.6 4.1 6.0 4.1 3.9 5.6 2.9 13.1 7.7 8.8 1.2 0.8 13.2 1.9 4.5 6.0 2.0 13.2 8.8 16.7 6.1 1.3 3.5 21.9 12.7 4.0 4.1 3.8 4.7 3.1 5.0 4.7 1.8 7.5 0.7 12.3 11.3 20.6 10.3 7.1 6.3 4.1 1.5 4.7 4.0 3.9 10.4 21.8 0.0 6.1 6.9 17.6 10.2 2.3 3.1 3.1 7.6 7.3 3.0 4.1 ZNF551 DKFZp686H1038 ENSG00000204519 "Zinc finger protein 551" Q7Z340 19 57681969-57717301 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 5 "cerebellum: 6.4" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 30.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038187 Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 30: Non-specific - Translation" "Cluster 34: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nuclear speckles" "HPA038187: AB_2675884" "unprognostic (1.96e-1)" "unprognostic (3.02e-2)" "unprognostic (2.78e-1)" "unprognostic (1.04e-1)" "unprognostic (6.24e-3)" "unprognostic (1.30e-1)" "unprognostic (1.52e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (7.68e-5)" "unprognostic (2.92e-1)" "unprognostic (5.89e-2)" "unprognostic (4.83e-3)" "prognostic favorable (1.32e-4)" "unprognostic (4.70e-2)" "unprognostic (2.73e-1)" "unprognostic (1.26e-2)" "unprognostic (1.54e-1)" 1.9 2.3 0.9 3.4 1.0 7.9 4.0 6.4 1.1 2.3 2.9 2.4 2.2 1.9 1.8 2.2 2.9 1.7 2.2 1.1 0.7 2.4 1.7 1.9 5.0 0.6 0.9 3.3 2.5 3.3 6.3 2.6 0.4 2.7 2.5 4.9 2.5 2.4 2.0 3.7 2.4 2.4 0.7 3.6 2.7 4.3 1.1 5.1 6.1 1.8 4.9 2.6 1.6 1.2 3.9 8.4 10.2 7.5 1.9 2.4 10.8 4.6 3.2 6.3 2.9 7.2 3.7 7.0 2.9 3.4 4.6 4.3 6.9 10.4 9.7 0.0 30.3 12.4 0.3 3.2 1.8 8.8 10.8 4.1 3.8 6.4 5.8 3.5 2.6 7.2 8.6 0.0 5.6 3.6 18.3 3.4 21.6 7.4 13.5 11.4 17.7 9.3 2.5 22.0 9.9 8.1 6.9 4.3 3.5 9.7 5.5 11.5 3.2 7.2 7.4 2.4 8.6 7.3 17.0 15.7 1.3 4.3 6.9 1.2 1.2 1.3 1.8 1.9 3.3 3.8 2.7 2.9 2.8 2.8 4.3 4.1 0.6 3.1 1.0 2.2 2.3 2.3 0.9 1.0 6.4 1.1 1.1 0.7 0.6 0.9 0.4 0.7 1.1 1.2 2.2 6.4 3.9 2.6 5.4 5.2 6.3 2.6 1.8 7.7 4.7 2.8 1.8 2.8 6.3 1.8 8.4 4.1 4.5 2.3 1.9 3.1 13.8 2.0 3.3 3.3 2.4 11.2 1.1 1.0 3.0 2.8 2.0 3.8 1.3 6.0 4.6 2.4 2.6 3.3 1.4 4.1 4.1 4.4 2.1 4.1 3.4 2.4 1.8 1.0 1.7 2.7 3.1 2.0 0.9 1.9 1.7 4.9 3.3 5.0 1.6 0.7 4.5 13.8 0.0 2.3 2.4 8.7 12.8 4.6 7.1 2.9 4.8 3.3 4.7 7.6 ZNF560 FLJ31986 ENSG00000198028 "Zinc finger protein 560" Q96MR9 19 9466355-9498616 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "retina: 2.0;testis: 6.2" "Group enriched" "Detected in some" 5 "Early spermatids: 79.2;Late spermatids: 20.1" "Cancer enriched" "Detected in some" 7 "testis cancer: 7.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 20.5;HMC-1: 4.8;NTERA-2: 19.7;SuSa: 9.2" "HPA045439, HPA074438" Enhanced "Nucleoplasm,Nuclear speckles" NA NA "Cluster 77: Retina - Visual perception" "Cluster 36: HEL - Hemostasis" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "Nuclear speckles" "HPA045439: AB_2732520, HPA074438: " "unprognostic (4.43e-3)" "unprognostic (8.91e-2)" "unprognostic (9.85e-3)" "unprognostic (2.43e-2)" "unprognostic (1.17e-1)" "unprognostic (3.29e-1)" "unprognostic (1.04e-1)" "unprognostic (1.39e-1)" "unprognostic (6.57e-3)" "unprognostic (6.33e-5)" "unprognostic (5.60e-2)" "unprognostic (2.32e-1)" "unprognostic (9.15e-3)" "unprognostic (1.65e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.8 2.5 0.0 1.5 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.1 0.0 1.1 20.5 0.0 0.0 1.4 0.0 4.8 2.1 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 2.3 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 79.2 0.0 0.0 0.3 0.0 0.0 1.3 0.0 0.1 0.1 0.0 0.0 4.5 0.1 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 20.1 0.3 0.2 0.0 0.0 0.0 0.2 0.0 3.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 9.5 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ZNF572 FLJ38002 ENSG00000180938 "Zinc finger protein 572" Q7Z3I7 8 124973295-124979389 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 3.9;Inhibitory neurons: 2.5;Microglial cells: 2.8;Oligodendrocyte precursor cells: 2.5;Oligodendrocytes: 2.7;Spermatogonia: 2.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MCF7: 4.1" "Low region specificity" "Detected in all" HPA066838 Approved Approved "Nuclear speckles" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 40: Granulosa cells - Unknown function" "Nuclear speckles" "HPA066838: AB_2685734" "unprognostic (8.65e-2)" "unprognostic (3.11e-1)" "unprognostic (5.59e-2)" "unprognostic (2.33e-2)" "unprognostic (1.49e-3)" "unprognostic (8.37e-2)" "unprognostic (4.11e-2)" "unprognostic (1.81e-2)" "unprognostic (3.36e-1)" "unprognostic (8.88e-2)" "unprognostic (8.67e-2)" "unprognostic (2.42e-2)" "unprognostic (1.43e-1)" "unprognostic (8.95e-3)" "unprognostic (2.89e-1)" "unprognostic (2.82e-1)" "unprognostic (6.17e-2)" 0.6 0.3 0.9 1.0 1.3 0.1 1.8 1.0 1.2 1.1 0.7 1.0 0.9 1.4 2.2 0.5 1.5 0.7 0.9 0.8 1.0 1.7 0.9 0.7 1.9 1.4 1.1 2.3 1.0 0.6 0.4 1.5 1.1 1.4 1.3 1.9 1.3 1.5 0.2 0.8 0.9 0.8 1.1 1.5 1.4 3.6 1.1 1.9 1.8 0.2 1.9 1.1 0.8 1.6 1.0 0.5 1.1 0.0 1.5 1.7 0.0 0.3 0.1 1.3 0.7 1.4 0.7 2.5 1.6 0.4 0.2 1.9 0.6 0.0 1.1 0.0 0.5 0.0 0.7 1.7 1.2 0.0 1.2 1.3 1.6 1.3 0.0 0.3 0.8 0.0 1.5 0.0 1.7 4.1 0.0 0.0 0.0 2.4 0.0 1.6 2.8 0.3 0.7 0.7 2.5 2.4 1.5 2.4 2.6 2.1 1.0 1.6 0.5 1.5 1.7 0.4 0.0 0.0 1.4 1.1 0.3 0.0 0.1 0.0 0.1 0.3 0.2 0.3 0.4 0.6 0.2 0.1 0.1 0.6 0.8 0.5 0.0 0.7 0.2 0.0 0.0 0.1 0.9 1.3 1.0 1.2 0.8 1.0 1.4 1.1 1.1 1.1 1.1 1.6 0.2 0.0 0.0 3.9 0.8 0.1 0.2 0.0 0.0 1.0 0.3 0.4 0.6 0.0 0.6 0.0 0.0 0.9 0.2 0.2 1.9 0.3 0.5 0.9 0.5 0.4 0.0 0.4 1.3 0.2 0.3 0.4 0.0 0.3 0.0 1.6 0.4 0.3 0.4 0.0 2.5 0.1 0.0 0.3 0.0 0.4 0.0 0.2 0.0 2.8 0.6 2.3 1.0 2.5 2.7 0.0 0.1 1.2 0.0 0.1 0.1 1.0 0.9 0.6 0.0 0.1 0.2 2.4 2.8 0.3 0.0 0.3 0.3 0.5 0.6 0.1 ZNF584 FLJ39899 ENSG00000171574 "Zinc finger protein 584" Q8IVC4 19 58401504-58418327 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEK 293: 49.8" "Low region specificity" "Detected in all" "HPA043408, HPA048075" Uncertain Approved "Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nuclear speckles" "HPA043408: AB_2678466, HPA048075: AB_2680251" "unprognostic (6.06e-2)" "unprognostic (3.27e-3)" "unprognostic (3.76e-3)" "unprognostic (8.15e-3)" "unprognostic (5.50e-2)" "unprognostic (1.16e-2)" "unprognostic (1.23e-1)" "unprognostic (1.04e-2)" "unprognostic (6.33e-2)" "unprognostic (2.17e-1)" "unprognostic (1.01e-3)" "unprognostic (1.90e-3)" "unprognostic (1.66e-1)" "unprognostic (1.53e-1)" "unprognostic (1.80e-1)" "unprognostic (3.27e-1)" "unprognostic (1.36e-2)" 5.7 6.7 4.6 2.9 4.5 1.8 5.0 5.4 5.5 5.6 6.0 6.6 3.5 6.9 3.8 5.8 6.8 2.3 8.9 5.1 4.3 5.3 6.6 4.3 2.5 5.3 4.6 6.1 4.9 8.4 6.7 2.7 4.6 5.0 2.6 5.1 4.7 5.7 9.8 9.0 3.5 5.1 4.0 3.3 5.6 4.7 4.5 3.2 4.7 10.9 3.4 6.1 5.0 4.1 11.7 16.7 11.2 14.7 10.8 10.7 4.5 8.9 15.8 5.4 6.7 2.7 3.5 5.8 7.0 14.7 14.2 6.5 12.1 14.6 6.1 7.5 49.8 15.7 9.6 3.5 18.3 17.3 4.3 11.1 10.4 16.5 22.8 11.9 10.9 9.5 15.8 5.4 8.9 8.3 14.4 5.4 2.8 7.6 23.2 10.4 8.4 9.0 7.6 13.7 9.0 9.5 19.5 5.6 7.4 2.9 3.7 8.6 7.0 21.2 6.5 8.9 14.3 5.0 9.5 1.3 15.2 6.0 7.1 0.0 2.2 0.8 3.2 2.1 5.2 2.1 4.3 4.5 3.4 3.3 2.3 3.6 0.7 3.2 3.5 2.9 5.1 2.7 4.6 4.5 5.4 5.5 5.1 4.3 5.3 4.6 4.6 4.0 4.5 4.1 4.2 3.2 3.9 1.0 2.3 11.2 3.2 5.6 6.2 4.1 4.8 4.3 12.8 5.7 2.1 9.2 4.2 1.0 5.9 1.6 13.7 5.6 9.6 8.1 6.1 4.6 6.7 9.5 2.0 5.1 1.5 5.6 3.6 1.8 2.5 5.5 6.8 4.7 2.6 3.3 2.2 2.3 4.1 2.4 3.3 7.8 5.3 2.1 1.8 0.0 1.3 6.1 2.1 0.5 1.6 4.9 2.8 6.4 2.6 4.2 2.1 5.5 10.2 9.2 6.6 4.4 6.3 8.1 3.7 4.3 15.9 0.4 4.0 12.3 3.2 2.0 ZNF621 FLJ45246 ENSG00000172888 "Zinc finger protein 621" Q6ZSS3 3 40524878-40574685 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065518, HPA071440" Enhanced "Nuclear speckles" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "HPA065518: AB_2685501, HPA071440: AB_2686395" "unprognostic (1.09e-1)" "unprognostic (1.60e-1)" "unprognostic (4.20e-2)" "unprognostic (1.95e-1)" "unprognostic (2.45e-2)" "unprognostic (1.52e-3)" "unprognostic (9.50e-3)" "unprognostic (3.06e-2)" "unprognostic (3.14e-2)" "unprognostic (2.62e-1)" "unprognostic (4.04e-1)" "unprognostic (6.75e-3)" "unprognostic (2.19e-1)" "unprognostic (5.33e-2)" "unprognostic (8.76e-2)" "unprognostic (2.50e-2)" "unprognostic (2.01e-3)" 13.0 10.0 15.7 5.9 18.9 7.1 12.9 15.0 16.5 12.7 13.4 11.2 5.3 11.2 8.1 9.5 11.5 5.7 9.4 13.2 17.1 15.2 12.4 13.2 6.2 19.4 16.3 12.0 12.2 7.7 14.6 5.5 19.4 14.4 5.7 7.4 12.1 6.9 7.2 10.0 11.7 6.1 17.0 12.7 10.7 7.6 17.5 5.5 13.2 5.6 6.1 11.0 11.5 21.0 8.9 5.0 12.2 12.0 7.8 13.4 6.9 9.5 11.1 11.7 11.6 11.1 4.8 3.7 6.9 12.4 8.8 3.1 12.2 7.2 13.7 14.9 15.1 12.4 20.8 10.1 13.6 11.6 11.8 10.4 14.9 12.2 19.0 12.7 9.9 4.4 13.3 10.8 10.1 5.6 2.9 13.8 7.7 3.5 10.2 1.1 8.2 4.4 6.1 11.0 4.3 10.9 10.2 6.9 12.0 11.7 11.4 9.4 13.1 20.2 9.8 10.2 13.4 16.1 17.4 8.3 9.9 8.6 12.5 2.5 1.0 0.9 1.3 1.3 0.8 2.3 1.3 1.8 0.9 3.3 1.6 1.2 1.2 1.8 0.7 1.3 1.3 0.7 15.7 18.9 15.0 16.5 13.2 17.1 19.4 16.3 19.4 17.0 17.5 21.0 13.2 9.6 12.3 22.5 9.6 1.5 5.2 2.3 9.1 13.8 6.3 5.0 12.1 10.0 7.7 11.0 12.5 5.5 9.5 4.9 5.9 7.7 10.8 11.1 16.4 12.0 10.2 12.4 4.1 5.6 3.5 9.0 7.7 12.2 3.8 15.0 5.0 5.6 3.7 15.2 4.2 7.1 4.1 8.1 3.0 7.9 7.5 6.9 3.6 11.2 9.4 7.1 10.3 19.1 26.1 7.5 4.9 12.0 8.8 6.6 6.7 3.2 4.6 16.7 0.0 13.6 9.1 10.6 6.3 7.5 1.8 5.5 8.1 12.9 5.8 4.4 ZNF695 SBZF3 ENSG00000197472 "Zinc finger protein 695" Q8IW36 1 246945547-247008093 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 3.2;Extravillous trophoblasts: 4.7;Spermatocytes: 3.5;Spermatogonia: 2.8" "Cancer enhanced" "Detected in many" "testis cancer: 2.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" HPA024743 Uncertain Approved "Nuclear speckles" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear speckles" "HPA024743: AB_1859419" "unprognostic (8.46e-3)" "unprognostic (6.28e-2)" "unprognostic (1.82e-1)" "unprognostic (2.57e-4)" "unprognostic (4.51e-2)" "unprognostic (1.72e-1)" "unprognostic (1.10e-2)" "unprognostic (1.16e-1)" "unprognostic (5.71e-5)" "unprognostic (7.42e-4)" "unprognostic (2.81e-3)" "unprognostic (2.21e-2)" "unprognostic (1.05e-9)" "unprognostic (2.22e-1)" "unprognostic (2.07e-1)" "unprognostic (2.72e-1)" "unprognostic (3.87e-1)" 0.0 0.0 0.2 0.1 0.2 0.8 0.3 0.1 0.4 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.4 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.5 0.3 0.0 0.0 0.1 0.6 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.2 7.1 0.8 4.2 10.7 0.1 0.1 11.1 2.4 0.1 3.2 4.3 7.3 0.4 5.6 4.4 1.2 2.8 2.2 12.2 0.6 3.7 0.0 4.0 3.8 1.5 4.5 0.0 0.0 1.4 0.2 0.0 3.6 2.9 0.9 1.3 7.3 5.2 0.0 3.4 2.7 8.2 4.1 7.8 6.8 4.3 4.5 9.7 0.0 0.8 3.8 3.7 6.5 3.4 2.8 1.2 4.0 3.0 5.2 0.6 0.5 6.0 3.2 0.0 0.7 2.2 0.1 0.0 0.0 2.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.4 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.3 0.6 0.0 0.8 1.1 0.5 0.0 0.0 0.0 0.0 3.2 0.0 0.4 0.0 0.3 0.9 0.9 0.5 0.3 0.0 2.1 0.0 0.0 4.7 0.4 1.5 1.4 0.0 2.0 0.4 0.2 1.4 0.0 0.0 2.1 0.0 0.8 0.3 0.1 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.5 3.5 2.8 2.0 0.1 1.1 0.0 0.3 1.7 0.2 ZNF786 DKFZp762I137 ENSG00000197362 "Zinc finger protein 786" Q8N393 7 149069641-149090782 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 18.8;Horizontal cells: 18.5;Inhibitory neurons: 15.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021518, HPA053459" Uncertain Approved "Nucleoplasm,Nuclear speckles,Nuclear bodies" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear speckles" "Nucleoplasm, Nuclear bodies" "HPA021518: AB_2670734, HPA053459: AB_2682159" "unprognostic (3.13e-2)" "unprognostic (2.72e-1)" "unprognostic (5.61e-2)" "unprognostic (5.39e-2)" "unprognostic (1.87e-1)" "unprognostic (2.84e-2)" "prognostic unfavorable (1.09e-4)" "unprognostic (5.62e-2)" "unprognostic (1.09e-3)" "unprognostic (8.85e-2)" "prognostic favorable (2.01e-4)" "unprognostic (3.97e-2)" "unprognostic (1.39e-2)" "unprognostic (8.86e-3)" "unprognostic (1.31e-1)" "unprognostic (3.44e-1)" "unprognostic (1.47e-2)" 2.0 2.2 2.9 2.8 2.6 1.5 2.6 3.9 4.3 3.5 1.1 3.1 2.0 3.3 2.4 3.8 3.1 2.0 2.0 2.8 2.6 2.9 3.1 1.9 3.8 1.6 1.7 3.2 2.6 2.3 3.8 1.6 1.5 3.7 1.4 1.9 3.0 2.2 2.0 5.6 3.1 1.9 0.9 3.9 2.3 1.6 2.8 3.5 2.9 2.3 2.8 3.3 3.5 2.8 4.5 8.1 6.1 10.4 3.7 1.5 8.7 2.7 2.8 2.9 2.3 4.3 4.0 6.3 6.3 1.9 5.1 5.0 3.8 3.6 1.9 6.9 5.9 3.2 5.1 5.4 3.1 6.3 4.1 2.2 4.0 3.6 2.6 3.0 2.7 4.5 5.6 3.5 2.7 13.9 10.7 10.5 11.4 4.1 6.0 7.7 3.0 4.1 2.4 6.1 7.3 11.5 6.6 6.1 5.0 3.8 3.9 3.0 3.6 3.4 2.0 6.0 3.9 12.7 10.0 3.5 5.7 3.9 3.8 1.8 3.4 2.9 10.4 4.7 8.8 6.4 7.5 9.4 4.3 5.9 9.7 8.3 1.1 8.5 4.0 3.7 5.0 5.0 2.9 2.6 3.9 4.3 2.8 2.6 1.6 1.7 1.5 0.9 2.8 2.8 2.4 0.0 1.1 3.6 3.5 2.7 2.6 4.2 2.8 10.1 2.3 1.3 2.7 1.5 1.6 3.7 2.1 2.4 5.9 2.0 3.9 4.1 0.4 0.9 2.1 3.1 4.8 0.8 18.8 1.5 2.5 2.6 6.6 1.1 4.5 4.5 1.8 2.4 2.2 18.5 15.8 1.6 2.0 1.9 2.6 0.4 3.1 2.1 0.0 3.7 3.6 2.8 13.4 7.1 5.4 1.8 3.3 4.1 2.9 1.4 1.7 2.5 2.3 6.0 0.0 3.3 2.5 4.9 8.3 2.3 1.7 1.9 6.0 1.8 2.7 1.7 ZNF821 ENSG00000102984 "Zinc finger protein 821" O75541 16 71859680-71895336 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 21.2" "Cell type enhanced" "Detected in many" "Early spermatids: 143.0;Spermatocytes: 79.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 9.5;naive B-cell: 13.4;T-reg: 5.6" "Group enriched" "Detected in many" 9 "B-cells: 13.4;T-cells: 5.6" "Cell line enhanced" "Detected in many" "AF22: 13.2;SCLC-21H: 13.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036372, HPA042742" Enhanced Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 21: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Nuclear speckles" "HPA036372: AB_10669790, HPA042742: AB_2678140" "unprognostic (3.16e-1)" "unprognostic (1.77e-1)" "unprognostic (6.50e-2)" "unprognostic (1.12e-2)" "prognostic favorable (1.20e-4)" "unprognostic (1.69e-2)" "unprognostic (2.28e-2)" "unprognostic (7.72e-2)" "unprognostic (5.25e-2)" "unprognostic (3.04e-2)" "prognostic favorable (4.27e-5)" "unprognostic (2.83e-2)" "prognostic favorable (6.32e-10)" "unprognostic (1.82e-2)" "unprognostic (1.79e-1)" "unprognostic (7.97e-2)" "unprognostic (1.02e-1)" 2.1 2.8 5.4 1.5 5.7 2.5 3.3 9.8 6.0 6.0 2.9 2.8 1.4 4.4 7.5 2.6 3.1 2.6 2.8 5.7 6.7 4.0 1.8 2.9 4.4 5.2 5.0 4.9 2.3 4.1 8.9 1.7 5.3 4.2 3.4 9.3 3.3 3.3 3.6 5.3 4.3 1.9 4.7 3.9 2.5 21.2 5.8 3.3 4.2 4.1 5.4 2.0 4.2 4.8 1.1 0.9 13.2 6.4 2.6 3.3 2.2 1.4 3.0 2.9 4.6 1.9 0.8 2.5 2.3 2.6 3.2 1.9 4.4 2.0 3.5 3.9 5.0 0.5 0.8 0.8 1.6 0.9 2.8 2.9 3.2 2.0 1.2 5.0 2.3 0.6 1.7 1.8 3.2 3.3 1.5 0.9 5.2 3.9 0.6 6.0 2.8 4.5 3.3 0.4 13.2 6.3 1.8 1.1 1.5 5.6 4.5 3.0 4.5 3.1 3.2 1.1 0.9 4.4 2.4 10.2 1.0 2.5 3.0 0.0 0.5 0.4 2.0 0.0 1.8 9.5 2.1 1.5 0.9 13.4 1.3 0.5 0.4 1.0 0.5 0.0 5.6 0.8 5.4 5.7 9.8 6.0 5.7 6.7 5.2 5.0 5.3 4.7 5.8 4.8 7.4 0.0 4.2 13.7 28.7 8.0 8.7 7.2 23.3 41.8 15.2 12.4 1.2 11.5 4.9 16.5 45.9 5.8 11.8 23.5 21.5 9.7 143.0 8.5 11.5 8.4 23.4 6.1 28.3 4.8 5.2 7.7 29.0 14.8 9.5 13.5 12.5 1.8 7.9 32.0 30.4 11.3 6.1 10.6 13.4 57.4 12.5 10.3 3.6 8.4 3.7 25.8 9.2 22.1 13.7 6.2 16.7 12.4 22.6 8.0 42.8 10.8 4.7 51.6 13.1 6.3 9.2 79.4 20.8 16.1 7.5 6.2 15.4 6.3 7.7 4.3 ZNF843 MGC46336 ENSG00000176723 "Zinc finger protein 843" Q8N446 16 31432593-31443160 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 4.6;Cardiomyocytes: 5.3;Prostatic glandular cells: 3.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC diff: 2.3;EFO-21: 1.8;HMC-1: 1.6" "HPA030911, HPA030912, HPA077945" Uncertain Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "Nuclear speckles" "HPA030911: AB_2673656, HPA030912: AB_10670434, HPA077945: " "unprognostic (9.27e-2)" "unprognostic (1.32e-1)" "unprognostic (3.43e-3)" "unprognostic (9.24e-2)" "unprognostic (1.33e-1)" "unprognostic (6.25e-3)" "unprognostic (2.86e-1)" "unprognostic (8.30e-3)" "unprognostic (3.55e-1)" "unprognostic (1.22e-1)" "unprognostic (1.32e-3)" "unprognostic (2.93e-3)" "unprognostic (5.96e-3)" "unprognostic (1.23e-2)" "unprognostic (7.66e-2)" "unprognostic (1.28e-5)" "unprognostic (1.17e-1)" 0.6 0.5 1.5 0.3 1.2 0.3 0.6 2.5 1.3 1.0 0.0 0.4 0.2 1.0 0.7 0.4 1.1 0.7 1.7 1.6 1.9 0.6 0.4 0.3 0.3 1.1 1.4 3.0 2.1 0.9 1.5 0.4 0.9 0.6 0.1 1.1 1.5 0.8 2.2 0.9 0.3 0.5 1.1 0.4 0.4 0.5 1.8 0.2 1.0 0.8 0.2 0.5 0.6 0.9 0.1 0.3 0.2 1.2 2.3 0.6 0.0 0.2 0.2 0.0 0.1 0.1 0.3 0.0 1.8 0.3 0.1 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.2 0.0 0.6 0.2 1.6 1.2 0.3 0.0 0.1 0.8 0.0 0.2 0.2 0.2 0.6 0.8 0.1 0.4 0.7 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.7 0.7 0.1 0.3 0.2 0.1 0.2 0.0 0.2 0.2 0.8 0.0 0.2 0.1 0.1 0.0 0.1 0.4 1.0 0.2 0.2 0.7 0.1 0.4 0.2 0.2 0.7 0.1 0.2 0.1 0.4 0.7 1.7 0.1 0.2 0.1 1.0 1.5 1.2 2.5 1.3 1.6 1.9 1.1 1.4 0.9 1.1 1.8 0.9 0.5 0.0 0.5 2.9 0.3 0.8 4.6 0.1 0.0 2.2 0.9 1.3 5.3 0.0 0.7 0.0 2.1 0.3 0.1 0.3 0.0 0.3 0.2 0.4 2.0 1.0 1.2 0.0 1.4 0.2 0.1 1.4 0.0 0.4 1.3 1.4 1.8 0.3 0.6 0.0 1.7 0.0 0.0 0.3 2.1 0.0 1.5 0.9 0.0 0.0 0.1 1.4 2.1 1.0 1.3 0.1 0.1 1.5 0.1 3.6 0.0 0.4 0.0 1.9 0.0 2.8 1.3 0.4 0.7 0.1 1.4 0.3 1.2 0.8 0.1 1.9 ZNHIT6 "BCD1, C1orf181, FLJ20729, NY-BR-75" ENSG00000117174 "Zinc finger HIT-type containing 6" Q9NWK9 1 85649417-85708433 "Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018132 Uncertain Approved "Nuclear speckles,Vesicles" No No "Cluster 21: B-cells - Adaptive immune response" "Cluster 72: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nuclear speckles, Vesicles" "HPA018132: AB_1848789" "unprognostic (1.37e-1)" "unprognostic (4.01e-1)" "unprognostic (1.24e-1)" "unprognostic (2.27e-3)" "unprognostic (1.61e-2)" "unprognostic (1.11e-1)" "prognostic unfavorable (6.08e-6)" "unprognostic (1.11e-1)" "unprognostic (3.89e-2)" "unprognostic (8.48e-2)" "unprognostic (9.91e-3)" "unprognostic (2.92e-2)" "unprognostic (1.27e-3)" "unprognostic (5.91e-2)" "unprognostic (9.85e-2)" "unprognostic (1.15e-1)" "unprognostic (7.37e-2)" 10.3 6.6 7.2 5.2 8.2 5.2 10.1 6.8 7.7 14.6 5.3 9.7 2.9 11.0 4.4 11.8 9.6 3.6 7.7 6.8 7.9 9.0 6.7 6.9 6.4 7.7 7.4 10.4 7.2 4.2 7.5 4.7 7.6 8.9 4.2 3.3 9.5 4.4 7.8 11.1 7.9 5.5 8.1 8.1 6.9 6.1 7.6 5.5 8.5 3.9 6.0 11.6 11.3 9.1 13.5 9.1 8.9 8.1 19.2 17.4 11.3 17.0 16.3 11.5 11.0 9.2 6.8 10.4 19.7 10.4 24.7 11.2 15.9 10.9 18.6 14.3 13.7 21.6 10.3 10.7 16.2 35.4 8.3 17.2 10.0 15.3 13.4 11.4 13.7 16.4 20.2 13.3 17.6 5.1 20.9 9.2 13.5 11.0 16.5 16.6 19.7 12.0 18.7 25.2 8.6 5.6 13.3 20.3 19.3 9.3 9.0 8.9 15.6 14.8 10.0 12.5 24.7 8.5 9.3 28.2 3.4 22.0 13.1 0.6 0.7 0.1 1.8 0.7 2.0 1.9 1.6 2.0 1.2 2.4 2.0 2.0 0.1 1.8 0.7 2.1 1.8 0.8 7.2 8.2 6.8 7.7 6.8 7.9 7.7 7.4 7.6 8.1 7.6 9.1 22.0 16.0 22.5 22.5 20.3 16.2 14.4 12.5 13.1 31.8 10.6 9.9 17.6 11.5 38.0 31.3 33.3 9.0 21.0 25.6 3.9 11.9 4.2 15.5 47.4 20.9 9.5 8.4 40.4 8.8 13.7 22.2 6.1 16.1 27.8 22.4 14.3 10.6 7.5 15.2 30.0 20.9 16.2 13.5 7.4 3.8 13.4 9.1 7.2 22.5 11.0 17.6 27.8 34.2 45.3 12.2 11.6 12.8 11.1 11.1 15.5 6.3 18.0 38.8 19.7 22.4 20.7 35.8 21.6 14.0 16.3 2.7 20.1 25.8 20.5 10.8 ZSCAN5A "MGC4161, ZNF495, ZSCAN5" ENSG00000131848 "Zinc finger and SCAN domain containing 5A" Q9BUG6 19 56219670-56368383 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 25.1" "Group enriched" "Detected in many" 6 "Early spermatids: 128.5;Late spermatids: 88.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA041263, HPA043123, HPA046836, HPA060667" Uncertain Uncertain "Nuclear speckles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 34: Spermatids - Unknown function" "Nuclear speckles" "HPA041263: AB_2677382, HPA043123: AB_2678328, HPA046836: AB_2679832, HPA060667: " "unprognostic (1.72e-1)" "unprognostic (3.19e-3)" "unprognostic (8.22e-4)" "unprognostic (1.65e-2)" "unprognostic (2.05e-3)" "unprognostic (6.99e-2)" "unprognostic (1.39e-3)" "unprognostic (3.10e-3)" "unprognostic (1.17e-1)" "unprognostic (2.42e-1)" "unprognostic (8.67e-4)" "unprognostic (1.14e-1)" "unprognostic (5.04e-2)" "unprognostic (2.10e-2)" "unprognostic (4.70e-2)" "unprognostic (6.15e-3)" "unprognostic (3.99e-3)" 3.1 3.2 3.5 3.6 4.0 2.5 2.8 3.3 3.4 3.4 5.3 3.8 3.9 3.7 2.0 3.0 7.1 2.6 4.1 3.6 3.6 3.6 2.6 3.1 2.8 3.7 4.0 3.5 2.6 3.8 3.3 2.0 3.8 3.0 4.5 2.3 3.2 2.4 4.1 4.3 3.4 3.9 3.3 2.8 2.6 25.1 3.6 4.5 3.2 3.5 3.4 3.7 3.2 3.4 5.9 5.0 7.1 8.6 5.7 3.6 10.4 3.4 7.2 10.3 6.1 10.1 3.4 10.6 2.7 6.0 6.1 7.0 9.2 7.3 9.2 3.0 19.4 13.0 3.4 10.2 4.5 14.5 14.0 2.8 11.0 10.1 4.6 2.1 7.5 8.2 5.3 4.7 3.2 7.2 3.5 8.0 12.8 5.2 13.1 5.5 10.7 6.1 4.3 10.9 6.9 6.9 9.1 6.9 3.6 4.0 3.0 13.2 4.1 8.9 8.9 4.7 11.4 7.7 21.1 7.2 11.5 14.2 3.5 3.7 6.5 4.4 4.2 7.2 6.4 3.3 4.4 3.2 7.5 1.9 5.7 3.0 0.5 1.3 4.5 9.3 1.2 3.7 3.5 4.0 3.3 3.4 3.6 3.6 3.7 4.0 3.8 3.3 3.6 3.4 3.3 0.0 4.2 2.3 5.3 4.8 5.8 6.0 6.2 4.9 6.4 5.0 17.4 0.0 5.0 0.0 8.4 3.0 5.6 4.3 11.7 5.0 128.5 10.5 3.4 4.1 7.8 5.5 0.6 5.1 3.5 5.5 5.1 4.9 2.5 2.8 4.6 6.8 6.5 3.3 0.3 4.0 8.2 7.3 3.0 88.5 2.5 5.2 0.0 0.0 3.0 7.8 2.1 0.5 0.3 4.4 1.0 2.6 4.0 4.5 4.5 6.0 12.4 10.8 0.0 6.5 3.3 14.7 16.5 4.2 3.7 7.0 3.4 3.3 5.2 3.3 ZSCAN5B "ZNF371, ZNF495B" ENSG00000197213 "Zinc finger and SCAN domain containing 5B" A6NJL1 19 56189570-56197920 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "testis: 1.3" "Cell type enriched" "Detected in single" 8 "Spermatogonia: 6.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043123, HPA046836, HPA059494, HPA060667" Uncertain Uncertain "Nuclear speckles" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nuclear speckles" "HPA043123: AB_2678328, HPA046836: AB_2679832, HPA059494: AB_2684038, HPA060667: " "unprognostic (4.73e-2)" "unprognostic (9.73e-2)" "unprognostic (3.43e-1)" "unprognostic (1.18e-1)" "unprognostic (1.06e-2)" "unprognostic (5.79e-2)" "unprognostic (2.88e-2)" "unprognostic (2.44e-1)" "unprognostic (5.15e-1)" "unprognostic (1.98e-1)" "unprognostic (7.01e-2)" "unprognostic (2.90e-1)" "unprognostic (2.55e-1)" "unprognostic (3.52e-2)" "unprognostic (2.24e-2)" "unprognostic (1.02e-1)" "unprognostic (2.83e-2)" 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ZSCAN5C "ZNF495C, ZSCAN5CP" ENSG00000204532 "Zinc finger and SCAN domain containing 5C" A6NGD5 19 56202273-56209200 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041263, HPA043123, HPA046836, HPA060667" Uncertain Uncertain "Nuclear speckles" NA NA "Nuclear speckles" "HPA041263: AB_2677382, HPA043123: AB_2678328, HPA046836: AB_2679832, HPA060667: " "unprognostic (3.74e-1)" "unprognostic (1.54e-1)" "unprognostic (3.29e-2)" "unprognostic (2.56e-2)" "unprognostic (9.17e-3)" "unprognostic (1.53e-1)" "unprognostic (1.47e-1)" "unprognostic (3.68e-2)" "unprognostic (4.01e-2)" "unprognostic (2.13e-2)" "unprognostic (7.45e-2)" "unprognostic (1.35e-1)" "unprognostic (8.51e-2)" "unprognostic (1.55e-1)" "unprognostic (7.89e-2)" "unprognostic (2.53e-1)" "unprognostic (9.53e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ZSWIM5 KIAA1511 ENSG00000162415 "Zinc finger SWIM-type containing 5" Q9P217 1 45016399-45306209 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 9 "Astrocytes: 96.9;Excitatory neurons: 84.3;Granulosa cells: 36.3;Inhibitory neurons: 133.8;Microglial cells: 54.4;Oligodendrocyte precursor cells: 144.8;Oligodendrocytes: 106.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 5.2;Hep G2: 6.1;SCLC-21H: 7.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018211 Uncertain Approved "Nuclear speckles" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear speckles" "HPA018211: AB_1859502" "unprognostic (1.86e-1)" "unprognostic (2.58e-1)" "unprognostic (3.06e-1)" "unprognostic (1.49e-3)" "unprognostic (3.19e-1)" "unprognostic (3.72e-2)" "unprognostic (1.72e-3)" "unprognostic (2.65e-2)" "unprognostic (1.57e-1)" "unprognostic (1.77e-1)" "unprognostic (5.88e-3)" "unprognostic (2.55e-1)" "unprognostic (4.12e-3)" "unprognostic (7.12e-2)" "unprognostic (3.09e-2)" "unprognostic (2.88e-2)" "unprognostic (1.16e-1)" 1.0 12.1 2.8 0.9 3.4 0.2 1.7 5.4 3.1 2.2 0.9 4.1 4.4 3.0 2.4 1.3 2.4 1.1 1.5 2.6 3.3 2.9 0.6 2.1 1.1 3.0 3.2 8.0 2.9 6.0 6.0 0.9 2.9 3.1 4.9 8.5 2.9 2.3 1.2 1.5 6.8 3.0 2.2 1.6 1.9 3.0 3.5 0.7 4.1 1.1 0.9 2.6 1.3 2.5 0.4 1.3 3.1 5.2 0.4 0.1 0.7 0.1 4.2 0.8 0.6 0.4 0.5 0.3 0.1 0.1 2.3 0.1 2.2 0.0 0.9 2.2 3.9 0.2 4.6 6.1 0.0 0.6 0.6 0.1 0.1 0.2 0.0 0.4 0.9 1.0 0.2 0.2 0.1 1.8 0.4 0.2 2.8 3.7 1.5 1.4 0.1 0.2 0.0 1.0 7.2 3.7 2.0 0.7 0.3 0.9 1.5 0.1 0.2 0.7 0.4 0.2 0.8 1.4 0.2 0.1 2.8 0.2 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 2.8 3.4 5.4 3.1 2.6 3.3 3.0 3.2 2.9 2.2 3.5 2.5 0.3 0.0 3.1 96.9 0.4 0.5 0.5 0.1 1.2 9.3 1.5 1.4 1.4 2.8 1.3 0.0 10.4 0.1 0.2 5.7 1.9 0.3 1.2 0.4 0.7 1.9 6.7 0.0 84.3 1.3 0.0 1.0 1.5 0.7 0.0 36.3 1.8 0.3 0.1 8.4 133.8 3.9 0.0 0.0 0.3 1.5 0.3 0.2 0.0 54.4 0.6 1.8 0.0 144.8 106.1 0.8 3.7 1.5 0.2 0.5 6.1 1.8 0.7 4.9 0.0 1.1 1.1 1.3 2.3 0.5 0.9 0.1 0.9 0.7 4.4 0.3