[{"Gene":"AKR1C2","Gene synonym":["BABP","DD","DD2","DDH2","HAKRD","MCDR2","TDD"],"Ensembl":"ENSG00000151632","Gene description":"Aldo-keto reductase family 1 member C2","Uniprot":["P52895"],"Chromosome":"10","Position":"4987400-5018031","Protein class":["Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Lipid metabolism","Steroid metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"341.5","liver":"481.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"141.7","Club cells":"128.8","Gastric mucus-secreting cells":"133.5","Hepatocytes":"397.4","Urothelial cells":"271.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"cervical cancer":"21.7","head and neck cancer":"31.5","liver cancer":"50.2","lung cancer":"69.0","urothelial cancer":"35.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"A549":"2054.8","ASC diff":"2439.5","Hep G2":"3926.2","OE19":"2684.9","RT4":"1178.9"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB047304","HPA068265"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center","Endoplasmic reticulum","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Nucleoli fibrillar center","Endoplasmic reticulum"],"Antibody RRID":{"CAB047304":null,"HPA068265":"AB_2685966"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.88e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.65e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.58e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.60e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.30e-2"},"Tissue RNA - adipose tissue [nTPM]":"341.5","Tissue RNA - adrenal gland [nTPM]":"20.8","Tissue RNA - amygdala [nTPM]":"9.8","Tissue RNA - appendix [nTPM]":"10.0","Tissue RNA - basal ganglia [nTPM]":"11.6","Tissue RNA - bone marrow [nTPM]":"1.0","Tissue RNA - breast [nTPM]":"205.6","Tissue RNA - cerebellum [nTPM]":"10.7","Tissue RNA - cerebral cortex [nTPM]":"12.9","Tissue RNA - cervix [nTPM]":"17.4","Tissue RNA - choroid plexus [nTPM]":"8.1","Tissue RNA - colon [nTPM]":"37.1","Tissue RNA - duodenum [nTPM]":"29.6","Tissue RNA - endometrium 1 [nTPM]":"5.6","Tissue RNA - epididymis [nTPM]":"3.3","Tissue RNA - esophagus [nTPM]":"202.5","Tissue RNA - fallopian tube [nTPM]":"8.6","Tissue RNA - gallbladder [nTPM]":"98.1","Tissue RNA - heart muscle [nTPM]":"83.8","Tissue RNA - hippocampal formation [nTPM]":"7.2","Tissue RNA - hypothalamus [nTPM]":"16.6","Tissue RNA - kidney [nTPM]":"43.0","Tissue RNA - liver [nTPM]":"481.9","Tissue RNA - lung [nTPM]":"23.5","Tissue RNA - lymph node [nTPM]":"2.1","Tissue RNA - medulla oblongata [nTPM]":"18.7","Tissue RNA - midbrain [nTPM]":"13.7","Tissue RNA - ovary [nTPM]":"10.4","Tissue RNA - pancreas [nTPM]":"11.8","Tissue RNA - parathyroid gland [nTPM]":"1.1","Tissue RNA - pituitary gland [nTPM]":"8.1","Tissue RNA - placenta [nTPM]":"0.8","Tissue RNA - pons [nTPM]":"17.1","Tissue RNA - prostate [nTPM]":"11.7","Tissue RNA - rectum [nTPM]":"13.3","Tissue RNA - retina [nTPM]":"15.2","Tissue RNA - salivary gland [nTPM]":"116.5","Tissue RNA - seminal vesicle [nTPM]":"12.9","Tissue RNA - skeletal muscle [nTPM]":"286.9","Tissue RNA - skin 1 [nTPM]":"42.5","Tissue RNA - small intestine [nTPM]":"33.7","Tissue RNA - smooth muscle [nTPM]":"9.2","Tissue RNA - spinal cord [nTPM]":"11.5","Tissue RNA - spleen [nTPM]":"2.1","Tissue RNA - stomach 1 [nTPM]":"137.0","Tissue RNA - testis [nTPM]":"11.8","Tissue RNA - thalamus [nTPM]":"16.8","Tissue RNA - thymus [nTPM]":"4.4","Tissue RNA - thyroid gland [nTPM]":"38.3","Tissue RNA - tongue [nTPM]":"36.5","Tissue RNA - tonsil [nTPM]":"9.3","Tissue RNA - urinary bladder [nTPM]":"253.9","Tissue RNA - vagina [nTPM]":"47.0","Tissue RNA - white matter [nTPM]":"9.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"2054.8","Cell RNA - AF22 [nTPM]":"2.4","Cell RNA - AN3-CA [nTPM]":"214.1","Cell RNA - ASC diff [nTPM]":"2439.5","Cell RNA - ASC TERT1 [nTPM]":"83.4","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.7","Cell RNA - BJ hTERT+ [nTPM]":"8.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.0","Cell RNA - CACO-2 [nTPM]":"8.1","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.4","Cell RNA - EFO-21 [nTPM]":"11.5","Cell RNA - fHDF\/TERT166 [nTPM]":"14.2","Cell RNA - GAMG [nTPM]":"10.0","Cell RNA - HaCaT [nTPM]":"57.8","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"10.7","Cell RNA - HBF TERT88 [nTPM]":"1.2","Cell RNA - HDLM-2 [nTPM]":"0.6","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.7","Cell RNA - HeLa [nTPM]":"516.4","Cell RNA - Hep G2 [nTPM]":"3926.2","Cell RNA - HHSteC [nTPM]":"4.6","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"0.9","Cell RNA - HSkMC [nTPM]":"218.3","Cell RNA - hTCEpi [nTPM]":"126.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.5","Cell RNA - hTERT-HME1 [nTPM]":"10.4","Cell RNA - hTERT-RPE1 [nTPM]":"0.7","Cell RNA - HUVEC TERT2 [nTPM]":"0.9","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"81.9","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"20.4","Cell RNA - MCF7 [nTPM]":"3.3","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.7","Cell RNA - OE19 [nTPM]":"2684.9","Cell RNA - PC-3 [nTPM]":"0.8","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"0.6","Cell RNA - RPMI-8226 [nTPM]":"34.6","Cell RNA - RPTEC TERT1 [nTPM]":"19.0","Cell RNA - RT4 [nTPM]":"1178.9","Cell RNA - SCLC-21H [nTPM]":"1.2","Cell RNA - SH-SY5Y [nTPM]":"0.4","Cell RNA - SiHa [nTPM]":"21.2","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"0.5","Cell RNA - THP-1 [nTPM]":"4.0","Cell RNA - TIME [nTPM]":"8.6","Cell RNA - U-138 MG [nTPM]":"5.1","Cell RNA - U-2 OS [nTPM]":"1.8","Cell RNA - U-2197 [nTPM]":"74.6","Cell RNA - U-251 MG [nTPM]":"0.8","Cell RNA - U-266\/70 [nTPM]":"0.6","Cell RNA - U-266\/84 [nTPM]":"0.6","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"25.9","Cell RNA - U-937 [nTPM]":"30.9","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"9.8","Brain RNA - basal ganglia [nTPM]":"11.6","Brain RNA - cerebellum [nTPM]":"10.7","Brain RNA - cerebral cortex [nTPM]":"12.9","Brain RNA - hippocampal formation [nTPM]":"7.2","Brain RNA - hypothalamus [nTPM]":"16.6","Brain RNA - medulla oblongata [nTPM]":"18.7","Brain RNA - midbrain [nTPM]":"13.7","Brain RNA - pons [nTPM]":"17.1","Brain RNA - spinal cord [nTPM]":"11.5","Brain RNA - thalamus [nTPM]":"16.8","Brain RNA - white matter [nTPM]":"9.7","Single Cell Type RNA - Adipocytes [nTPM]":"15.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"9.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"141.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"20.5","Single Cell Type RNA - Bipolar cells [nTPM]":"1.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"102.9","Single Cell Type RNA - Club cells [nTPM]":"128.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"18.3","Single Cell Type RNA - Early spermatids [nTPM]":"17.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"7.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"8.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"103.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"44.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"133.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.8","Single Cell Type RNA - Hepatocytes [nTPM]":"397.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.4","Single Cell Type RNA - Ionocytes [nTPM]":"46.8","Single Cell Type RNA - Kupffer cells [nTPM]":"12.0","Single Cell Type RNA - Langerhans cells [nTPM]":"7.8","Single Cell Type RNA - Late spermatids [nTPM]":"7.8","Single Cell Type RNA - Leydig cells [nTPM]":"79.2","Single Cell Type RNA - Macrophages [nTPM]":"1.0","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"19.7","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"39.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"90.0","Single Cell Type RNA - Paneth cells [nTPM]":"6.6","Single Cell Type RNA - Peritubular cells [nTPM]":"78.6","Single Cell Type RNA - Plasma cells [nTPM]":"0.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"23.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"40.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"112.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.3","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.5","Single Cell Type RNA - Urothelial cells [nTPM]":"271.9"},{"Gene":"AKR1C3","Gene synonym":["DDX","HAKRB","HSD17B5","KIAA0119","PGFS"],"Ensembl":"ENSG00000196139","Gene description":"Aldo-keto reductase family 1 member C3","Uniprot":["P42330"],"Chromosome":"10","Position":"5035354-5107686","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"441.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"393.1","Exocrine glandular cells":"722.5","Proximal enterocytes":"576.9","Proximal tubular cells":"601.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"83.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"244.0","gdT-cell":"102.6"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"244.0","T-cells":"102.6"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"1615.1","ASC diff":"811.9","Hep G2":"699.6","OE19":"3025.3","RT4":"639.2"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010874","HPA068265"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center","Endoplasmic reticulum","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"19000000","Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 1: Pancreatic cells - Digestion","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Nucleoli fibrillar center","Endoplasmic reticulum"],"Antibody RRID":{"CAB010874":"AB_476751","HPA068265":"AB_2685966"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.96e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.74e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.08e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.22e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.24e-3"},"Tissue RNA - adipose tissue [nTPM]":"164.4","Tissue RNA - adrenal gland [nTPM]":"50.2","Tissue RNA - amygdala [nTPM]":"31.1","Tissue RNA - appendix [nTPM]":"25.4","Tissue RNA - basal ganglia [nTPM]":"34.6","Tissue RNA - bone marrow [nTPM]":"42.3","Tissue RNA - breast [nTPM]":"115.2","Tissue RNA - cerebellum [nTPM]":"32.1","Tissue RNA - cerebral cortex [nTPM]":"42.4","Tissue RNA - cervix [nTPM]":"21.9","Tissue RNA - choroid plexus [nTPM]":"30.2","Tissue RNA - colon [nTPM]":"185.9","Tissue RNA - duodenum [nTPM]":"441.3","Tissue RNA - endometrium 1 [nTPM]":"25.9","Tissue RNA - epididymis [nTPM]":"4.4","Tissue RNA - esophagus [nTPM]":"53.2","Tissue RNA - fallopian tube [nTPM]":"42.1","Tissue RNA - gallbladder [nTPM]":"261.1","Tissue RNA - heart muscle [nTPM]":"42.9","Tissue RNA - hippocampal formation [nTPM]":"31.5","Tissue RNA - hypothalamus [nTPM]":"35.6","Tissue RNA - kidney [nTPM]":"177.7","Tissue RNA - liver [nTPM]":"268.0","Tissue RNA - lung [nTPM]":"48.3","Tissue RNA - lymph node [nTPM]":"7.6","Tissue RNA - medulla oblongata [nTPM]":"30.3","Tissue RNA - midbrain [nTPM]":"33.9","Tissue RNA - ovary [nTPM]":"17.8","Tissue RNA - pancreas [nTPM]":"36.4","Tissue RNA - parathyroid gland [nTPM]":"22.5","Tissue RNA - pituitary gland [nTPM]":"10.4","Tissue RNA - placenta [nTPM]":"4.7","Tissue RNA - pons [nTPM]":"32.3","Tissue RNA - prostate [nTPM]":"10.3","Tissue RNA - rectum [nTPM]":"98.0","Tissue RNA - retina [nTPM]":"19.1","Tissue RNA - salivary gland [nTPM]":"40.5","Tissue RNA - seminal vesicle [nTPM]":"19.4","Tissue RNA - skeletal muscle [nTPM]":"116.9","Tissue RNA - skin 1 [nTPM]":"27.0","Tissue RNA - small intestine [nTPM]":"270.9","Tissue RNA - smooth muscle [nTPM]":"39.2","Tissue RNA - spinal cord [nTPM]":"30.3","Tissue RNA - spleen [nTPM]":"3.8","Tissue RNA - stomach 1 [nTPM]":"237.4","Tissue RNA - testis [nTPM]":"10.0","Tissue RNA - thalamus [nTPM]":"31.5","Tissue RNA - thymus [nTPM]":"37.4","Tissue RNA - thyroid gland [nTPM]":"26.4","Tissue RNA - tongue [nTPM]":"34.8","Tissue RNA - tonsil [nTPM]":"6.6","Tissue RNA - urinary bladder [nTPM]":"84.7","Tissue RNA - vagina [nTPM]":"22.2","Tissue RNA - white matter [nTPM]":"31.1","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"1615.1","Cell RNA - AF22 [nTPM]":"1.1","Cell RNA - AN3-CA [nTPM]":"413.0","Cell RNA - ASC diff [nTPM]":"811.9","Cell RNA - ASC TERT1 [nTPM]":"292.2","Cell RNA - BEWO [nTPM]":"1.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"21.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.4","Cell RNA - CACO-2 [nTPM]":"47.6","Cell RNA - CAPAN-2 [nTPM]":"24.5","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"78.7","Cell RNA - fHDF\/TERT166 [nTPM]":"19.4","Cell RNA - GAMG [nTPM]":"45.0","Cell RNA - HaCaT [nTPM]":"11.5","Cell RNA - HAP1 [nTPM]":"1.5","Cell RNA - HBEC3-KT [nTPM]":"28.8","Cell RNA - HBF TERT88 [nTPM]":"1.1","Cell RNA - HDLM-2 [nTPM]":"3.0","Cell RNA - HEK 293 [nTPM]":"0.5","Cell RNA - HEL [nTPM]":"3.2","Cell RNA - HeLa [nTPM]":"438.4","Cell RNA - Hep G2 [nTPM]":"699.6","Cell RNA - HHSteC [nTPM]":"4.3","Cell RNA - HL-60 [nTPM]":"0.7","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"160.9","Cell RNA - hTCEpi [nTPM]":"57.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"20.0","Cell RNA - hTERT-HME1 [nTPM]":"0.7","Cell RNA - hTERT-RPE1 [nTPM]":"25.8","Cell RNA - HUVEC TERT2 [nTPM]":"28.1","Cell RNA - JURKAT [nTPM]":"3.4","Cell RNA - K-562 [nTPM]":"10.8","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"42.6","Cell RNA - MCF7 [nTPM]":"3.8","Cell RNA - MOLT-4 [nTPM]":"9.8","Cell RNA - NB-4 [nTPM]":"2.6","Cell RNA - NTERA-2 [nTPM]":"0.7","Cell RNA - OE19 [nTPM]":"3025.3","Cell RNA - PC-3 [nTPM]":"4.3","Cell RNA - REH [nTPM]":"3.3","Cell RNA - RH-30 [nTPM]":"9.6","Cell RNA - RPMI-8226 [nTPM]":"43.7","Cell RNA - RPTEC TERT1 [nTPM]":"149.0","Cell RNA - RT4 [nTPM]":"639.2","Cell RNA - SCLC-21H [nTPM]":"1.0","Cell RNA - SH-SY5Y [nTPM]":"2.9","Cell RNA - SiHa [nTPM]":"232.2","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"0.9","Cell RNA - T-47d [nTPM]":"0.5","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"221.7","Cell RNA - U-138 MG [nTPM]":"5.2","Cell RNA - U-2 OS [nTPM]":"4.7","Cell RNA - U-2197 [nTPM]":"87.8","Cell RNA - U-251 MG [nTPM]":"3.1","Cell RNA - U-266\/70 [nTPM]":"0.7","Cell RNA - U-266\/84 [nTPM]":"0.7","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"45.8","Cell RNA - U-937 [nTPM]":"62.8","Cell RNA - WM-115 [nTPM]":"4.4","Blood RNA - basophil [nTPM]":"244.0","Blood RNA - classical monocyte [nTPM]":"2.9","Blood RNA - eosinophil [nTPM]":"4.8","Blood RNA - gdT-cell [nTPM]":"102.6","Blood RNA - intermediate monocyte [nTPM]":"0.9","Blood RNA - MAIT T-cell [nTPM]":"6.9","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"19.0","Blood RNA - memory CD8 T-cell [nTPM]":"18.7","Blood RNA - myeloid DC [nTPM]":"2.1","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"11.6","Blood RNA - naive CD8 T-cell [nTPM]":"8.9","Blood RNA - neutrophil [nTPM]":"7.3","Blood RNA - NK-cell [nTPM]":"21.1","Blood RNA - non-classical monocyte [nTPM]":"1.4","Blood RNA - plasmacytoid DC [nTPM]":"39.6","Blood RNA - T-reg [nTPM]":"21.4","Blood RNA - total PBMC [nTPM]":"42.4","Brain RNA - amygdala [nTPM]":"31.1","Brain RNA - basal ganglia [nTPM]":"34.6","Brain RNA - cerebellum [nTPM]":"32.1","Brain RNA - cerebral cortex [nTPM]":"42.4","Brain RNA - hippocampal formation [nTPM]":"31.5","Brain RNA - hypothalamus [nTPM]":"35.6","Brain RNA - medulla oblongata [nTPM]":"30.3","Brain RNA - midbrain [nTPM]":"33.9","Brain RNA - pons [nTPM]":"32.3","Brain RNA - spinal cord [nTPM]":"30.3","Brain RNA - thalamus [nTPM]":"31.5","Brain RNA - white matter [nTPM]":"31.1","Single Cell Type RNA - Adipocytes [nTPM]":"144.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.3","Single Cell Type RNA - Astrocytes [nTPM]":"4.9","Single Cell Type RNA - B-cells [nTPM]":"4.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"393.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"2.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"172.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"36.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"64.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"133.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"43.0","Single Cell Type RNA - Ductal cells [nTPM]":"114.6","Single Cell Type RNA - Early spermatids [nTPM]":"3.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"67.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.5","Single Cell Type RNA - Endothelial cells [nTPM]":"67.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.2","Single Cell Type RNA - Erythroid cells [nTPM]":"34.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"722.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"44.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"158.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"66.4","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.6","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"65.9","Single Cell Type RNA - Ionocytes [nTPM]":"61.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"14.0","Single Cell Type RNA - Late spermatids [nTPM]":"4.9","Single Cell Type RNA - Leydig cells [nTPM]":"78.3","Single Cell Type RNA - Macrophages [nTPM]":"14.8","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"4.1","Single Cell Type RNA - Muller glia cells [nTPM]":"132.7","Single Cell Type RNA - NK-cells [nTPM]":"202.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"266.1","Single Cell Type RNA - Paneth cells [nTPM]":"219.6","Single Cell Type RNA - Peritubular cells [nTPM]":"106.8","Single Cell Type RNA - Plasma cells [nTPM]":"3.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"576.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"601.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"112.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.3","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"4.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"14.4","Single Cell Type RNA - Theca cells [nTPM]":"7.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"196.9","Single Cell Type RNA - Urothelial cells [nTPM]":"46.4"},{"Gene":"AKR1C4","Gene synonym":["3-alpha-HSD","C11","CDR","CHDR","DD4","HAKRA","MGC22581"],"Ensembl":"ENSG00000198610","Gene description":"Aldo-keto reductase family 1 member C4","Uniprot":["P17516"],"Chromosome":"10","Position":"5195462-5218949","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"17","RNA tissue specific nTPM":{"liver":"717.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"16","RNA single cell type specific nTPM":{"Hepatocytes":"613.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"86","RNA cancer specific FPKM":{"liver cancer":"108.4"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"HDLM-2":"6.6","OE19":"2.9"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044720","HPA068265"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center","Endoplasmic reticulum","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3800000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 60: Liver - Hemostasis & Lipid metabolism","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Nucleoli fibrillar center","Endoplasmic reticulum"],"Antibody RRID":{"HPA044720":"AB_2679058","HPA068265":"AB_2685966"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"2.5","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"41.8","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"717.5","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"1.2","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"1.1","Tissue RNA - testis [nTPM]":"0.7","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.8","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.6","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"6.6","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"1.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"2.9","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"37.1","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"7.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"13.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"613.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.6","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"14.5","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"2.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.8","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"ALDOC","Gene synonym":[],"Ensembl":"ENSG00000109107","Gene description":"Aldolase, fructose-bisphosphate C","Uniprot":["P09972"],"Chromosome":"17","Position":"28573115-28576948","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Glycolysis"],"Molecular function":["Lyase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"1384.6","choroid plexus":"589.6","retina":"1183.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"112.5","Horizontal cells":"274.2","Muller glia cells":"127.1","Proximal enterocytes":"120.0","Rod photoreceptor cells":"348.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"glioma":"128.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RPMI-8226":"250.9","U-266\/70":"161.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003282","CAB020828","HPA067442"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"150000000","Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Nucleoplasm","Nucleoli fibrillar center"],"Subcellular additional location":["Vesicles","Cytosol"],"Antibody RRID":{"CAB020828":null,"HPA003282":"AB_1078130","HPA067442":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.45e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.69e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.56e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.80e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.29e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Tissue RNA - adipose tissue [nTPM]":"87.0","Tissue RNA - adrenal gland [nTPM]":"24.3","Tissue RNA - amygdala [nTPM]":"953.6","Tissue RNA - appendix [nTPM]":"12.7","Tissue RNA - basal ganglia [nTPM]":"909.7","Tissue RNA - bone marrow [nTPM]":"23.6","Tissue RNA - breast [nTPM]":"42.5","Tissue RNA - cerebellum [nTPM]":"1238.3","Tissue RNA - cerebral cortex [nTPM]":"1162.3","Tissue RNA - cervix [nTPM]":"39.3","Tissue RNA - choroid plexus [nTPM]":"589.6","Tissue RNA - colon [nTPM]":"18.5","Tissue RNA - duodenum [nTPM]":"18.7","Tissue RNA - endometrium 1 [nTPM]":"17.9","Tissue RNA - epididymis [nTPM]":"10.9","Tissue RNA - esophagus [nTPM]":"40.8","Tissue RNA - fallopian tube [nTPM]":"14.3","Tissue RNA - gallbladder [nTPM]":"10.9","Tissue RNA - heart muscle [nTPM]":"285.5","Tissue RNA - hippocampal formation [nTPM]":"955.7","Tissue RNA - hypothalamus [nTPM]":"958.0","Tissue RNA - kidney [nTPM]":"16.8","Tissue RNA - liver [nTPM]":"98.3","Tissue RNA - lung [nTPM]":"13.7","Tissue RNA - lymph node [nTPM]":"19.3","Tissue RNA - medulla oblongata [nTPM]":"1297.5","Tissue RNA - midbrain [nTPM]":"962.6","Tissue RNA - ovary [nTPM]":"39.1","Tissue RNA - pancreas [nTPM]":"4.9","Tissue RNA - parathyroid gland [nTPM]":"12.1","Tissue RNA - pituitary gland [nTPM]":"30.6","Tissue RNA - placenta [nTPM]":"4.1","Tissue RNA - pons [nTPM]":"1384.6","Tissue RNA - prostate [nTPM]":"18.9","Tissue RNA - rectum [nTPM]":"14.7","Tissue RNA - retina [nTPM]":"1183.1","Tissue RNA - salivary gland [nTPM]":"19.9","Tissue RNA - seminal vesicle [nTPM]":"15.8","Tissue RNA - skeletal muscle [nTPM]":"4.8","Tissue RNA - skin 1 [nTPM]":"74.5","Tissue RNA - small intestine [nTPM]":"43.9","Tissue RNA - smooth muscle [nTPM]":"12.4","Tissue RNA - spinal cord [nTPM]":"926.9","Tissue RNA - spleen [nTPM]":"24.4","Tissue RNA - stomach 1 [nTPM]":"23.3","Tissue RNA - testis [nTPM]":"14.2","Tissue RNA - thalamus [nTPM]":"1090.2","Tissue RNA - thymus [nTPM]":"9.6","Tissue RNA - thyroid gland [nTPM]":"7.4","Tissue RNA - tongue [nTPM]":"8.1","Tissue RNA - tonsil [nTPM]":"30.5","Tissue RNA - urinary bladder [nTPM]":"19.0","Tissue RNA - vagina [nTPM]":"47.0","Tissue RNA - white matter [nTPM]":"886.1","Cell RNA - A-431 [nTPM]":"29.9","Cell RNA - A549 [nTPM]":"2.1","Cell RNA - AF22 [nTPM]":"13.7","Cell RNA - AN3-CA [nTPM]":"55.7","Cell RNA - ASC diff [nTPM]":"29.9","Cell RNA - ASC TERT1 [nTPM]":"32.9","Cell RNA - BEWO [nTPM]":"2.9","Cell RNA - BJ [nTPM]":"16.7","Cell RNA - BJ hTERT+ [nTPM]":"37.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"12.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"76.0","Cell RNA - CACO-2 [nTPM]":"17.9","Cell RNA - CAPAN-2 [nTPM]":"3.0","Cell RNA - Daudi [nTPM]":"14.9","Cell RNA - EFO-21 [nTPM]":"17.3","Cell RNA - fHDF\/TERT166 [nTPM]":"15.5","Cell RNA - GAMG [nTPM]":"3.3","Cell RNA - HaCaT [nTPM]":"36.9","Cell RNA - HAP1 [nTPM]":"10.3","Cell RNA - HBEC3-KT [nTPM]":"102.3","Cell RNA - HBF TERT88 [nTPM]":"23.4","Cell RNA - HDLM-2 [nTPM]":"12.4","Cell RNA - HEK 293 [nTPM]":"8.9","Cell RNA - HEL [nTPM]":"28.3","Cell RNA - HeLa [nTPM]":"11.6","Cell RNA - Hep G2 [nTPM]":"30.4","Cell RNA - HHSteC [nTPM]":"25.8","Cell RNA - HL-60 [nTPM]":"10.0","Cell RNA - HMC-1 [nTPM]":"29.2","Cell RNA - HSkMC [nTPM]":"27.8","Cell RNA - hTCEpi [nTPM]":"13.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.5","Cell RNA - hTERT-HME1 [nTPM]":"24.0","Cell RNA - hTERT-RPE1 [nTPM]":"1.7","Cell RNA - HUVEC TERT2 [nTPM]":"5.3","Cell RNA - JURKAT [nTPM]":"29.7","Cell RNA - K-562 [nTPM]":"19.3","Cell RNA - Karpas-707 [nTPM]":"71.9","Cell RNA - LHCN-M2 [nTPM]":"10.7","Cell RNA - MCF7 [nTPM]":"15.1","Cell RNA - MOLT-4 [nTPM]":"11.9","Cell RNA - NB-4 [nTPM]":"32.0","Cell RNA - NTERA-2 [nTPM]":"20.8","Cell RNA - OE19 [nTPM]":"6.7","Cell RNA - PC-3 [nTPM]":"15.3","Cell RNA - REH [nTPM]":"9.5","Cell RNA - RH-30 [nTPM]":"1.6","Cell RNA - RPMI-8226 [nTPM]":"250.9","Cell RNA - RPTEC TERT1 [nTPM]":"1.9","Cell RNA - RT4 [nTPM]":"4.3","Cell RNA - SCLC-21H [nTPM]":"36.2","Cell RNA - SH-SY5Y [nTPM]":"61.9","Cell RNA - SiHa [nTPM]":"9.1","Cell RNA - SK-BR-3 [nTPM]":"67.3","Cell RNA - SK-MEL-30 [nTPM]":"0.5","Cell RNA - SuSa [nTPM]":"20.8","Cell RNA - T-47d [nTPM]":"36.6","Cell RNA - THP-1 [nTPM]":"21.2","Cell RNA - TIME [nTPM]":"3.5","Cell RNA - U-138 MG [nTPM]":"1.2","Cell RNA - U-2 OS [nTPM]":"5.3","Cell RNA - U-2197 [nTPM]":"2.1","Cell RNA - U-251 MG [nTPM]":"2.4","Cell RNA - U-266\/70 [nTPM]":"161.0","Cell RNA - U-266\/84 [nTPM]":"51.4","Cell RNA - U-698 [nTPM]":"10.9","Cell RNA - U-87 MG [nTPM]":"105.2","Cell RNA - U-937 [nTPM]":"28.0","Cell RNA - WM-115 [nTPM]":"1.9","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"7.4","Blood RNA - eosinophil [nTPM]":"3.0","Blood RNA - gdT-cell [nTPM]":"21.6","Blood RNA - intermediate monocyte [nTPM]":"8.7","Blood RNA - MAIT T-cell [nTPM]":"30.6","Blood RNA - memory B-cell [nTPM]":"24.0","Blood RNA - memory CD4 T-cell [nTPM]":"29.5","Blood RNA - memory CD8 T-cell [nTPM]":"17.8","Blood RNA - myeloid DC [nTPM]":"9.4","Blood RNA - naive B-cell [nTPM]":"25.1","Blood RNA - naive CD4 T-cell [nTPM]":"37.7","Blood RNA - naive CD8 T-cell [nTPM]":"28.4","Blood RNA - neutrophil [nTPM]":"18.0","Blood RNA - NK-cell [nTPM]":"29.4","Blood RNA - non-classical monocyte [nTPM]":"5.3","Blood RNA - plasmacytoid DC [nTPM]":"4.6","Blood RNA - T-reg [nTPM]":"40.9","Blood RNA - total PBMC [nTPM]":"19.0","Brain RNA - amygdala [nTPM]":"953.6","Brain RNA - basal ganglia [nTPM]":"909.7","Brain RNA - cerebellum [nTPM]":"1238.3","Brain RNA - cerebral cortex [nTPM]":"1162.3","Brain RNA - hippocampal formation [nTPM]":"955.7","Brain RNA - hypothalamus [nTPM]":"958.0","Brain RNA - medulla oblongata [nTPM]":"1297.5","Brain RNA - midbrain [nTPM]":"962.6","Brain RNA - pons [nTPM]":"1384.6","Brain RNA - spinal cord [nTPM]":"926.9","Brain RNA - thalamus [nTPM]":"1090.2","Brain RNA - white matter [nTPM]":"886.1","Single Cell Type RNA - Adipocytes [nTPM]":"4.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.8","Single Cell Type RNA - Astrocytes [nTPM]":"97.6","Single Cell Type RNA - B-cells [nTPM]":"9.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"80.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"112.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"22.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"29.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"106.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - dendritic cells [nTPM]":"9.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"31.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"21.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.0","Single Cell Type RNA - Endothelial cells [nTPM]":"11.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.6","Single Cell Type RNA - Erythroid cells [nTPM]":"3.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.5","Single Cell Type RNA - Fibroblasts [nTPM]":"5.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.2","Single Cell Type RNA - granulocytes [nTPM]":"13.3","Single Cell Type RNA - Granulosa cells [nTPM]":"4.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.3","Single Cell Type RNA - Hepatocytes [nTPM]":"93.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.4","Single Cell Type RNA - Horizontal cells [nTPM]":"274.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"41.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.9","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"4.4","Single Cell Type RNA - Langerhans cells [nTPM]":"5.3","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"9.3","Single Cell Type RNA - Macrophages [nTPM]":"3.1","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"21.5","Single Cell Type RNA - monocytes [nTPM]":"34.1","Single Cell Type RNA - Muller glia cells [nTPM]":"127.1","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"26.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.4","Single Cell Type RNA - Paneth cells [nTPM]":"12.4","Single Cell Type RNA - Peritubular cells [nTPM]":"10.1","Single Cell Type RNA - Plasma cells [nTPM]":"2.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"120.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"348.5","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"3.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - T-cells [nTPM]":"17.0","Single Cell Type RNA - Theca cells [nTPM]":"11.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.1","Single Cell Type RNA - Urothelial cells [nTPM]":"7.8"},{"Gene":"CDK7","Gene synonym":["CAK","CAK1","CDKN7","MO15","STK1"],"Ensembl":"ENSG00000134058","Gene description":"Cyclin dependent kinase 7","Uniprot":["P50613"],"Chromosome":"5","Position":"69234795-69277430","Protein class":["Cancer-related genes","Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","DNA damage","DNA repair","Transcription","Transcription regulation"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"121.0","Extravillous trophoblasts":"343.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"169.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004364","HPA007932","HPA008453","CAB079975"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 38: Extravillous trophoblasts - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli fibrillar center","Plasma membrane","Cytosol"],"Antibody RRID":{"CAB004364":"AB_627243","CAB079975":null,"HPA007932":"AB_1078492","HPA008453":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.77e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.09e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.42e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Tissue RNA - adipose tissue [nTPM]":"13.4","Tissue RNA - adrenal gland [nTPM]":"19.8","Tissue RNA - amygdala [nTPM]":"9.4","Tissue RNA - appendix [nTPM]":"9.5","Tissue RNA - basal ganglia [nTPM]":"10.2","Tissue RNA - bone marrow [nTPM]":"29.1","Tissue RNA - breast [nTPM]":"14.8","Tissue RNA - cerebellum [nTPM]":"10.9","Tissue RNA - cerebral cortex [nTPM]":"12.9","Tissue RNA - cervix [nTPM]":"17.5","Tissue RNA - choroid plexus [nTPM]":"11.5","Tissue RNA - colon [nTPM]":"13.7","Tissue RNA - duodenum [nTPM]":"13.3","Tissue RNA - endometrium 1 [nTPM]":"12.1","Tissue RNA - epididymis [nTPM]":"12.9","Tissue RNA - esophagus [nTPM]":"37.3","Tissue RNA - fallopian tube [nTPM]":"12.5","Tissue RNA - gallbladder [nTPM]":"6.4","Tissue RNA - heart muscle [nTPM]":"12.4","Tissue RNA - hippocampal formation [nTPM]":"9.5","Tissue RNA - hypothalamus [nTPM]":"10.5","Tissue RNA - kidney [nTPM]":"18.4","Tissue RNA - liver [nTPM]":"13.6","Tissue RNA - lung [nTPM]":"12.7","Tissue RNA - lymph node [nTPM]":"4.8","Tissue RNA - medulla oblongata [nTPM]":"9.7","Tissue RNA - midbrain [nTPM]":"9.7","Tissue RNA - ovary [nTPM]":"11.7","Tissue RNA - pancreas [nTPM]":"14.1","Tissue RNA - parathyroid gland [nTPM]":"3.2","Tissue RNA - pituitary gland [nTPM]":"18.2","Tissue RNA - placenta [nTPM]":"16.2","Tissue RNA - pons [nTPM]":"9.8","Tissue RNA - prostate [nTPM]":"13.7","Tissue RNA - rectum [nTPM]":"7.4","Tissue RNA - retina [nTPM]":"12.8","Tissue RNA - salivary gland [nTPM]":"18.9","Tissue RNA - seminal vesicle [nTPM]":"4.8","Tissue RNA - skeletal muscle [nTPM]":"26.8","Tissue RNA - skin 1 [nTPM]":"25.3","Tissue RNA - small intestine [nTPM]":"12.2","Tissue RNA - smooth muscle [nTPM]":"7.7","Tissue RNA - spinal cord [nTPM]":"9.8","Tissue RNA - spleen [nTPM]":"12.6","Tissue RNA - stomach 1 [nTPM]":"13.5","Tissue RNA - testis [nTPM]":"30.6","Tissue RNA - thalamus [nTPM]":"10.0","Tissue RNA - thymus [nTPM]":"9.3","Tissue RNA - thyroid gland [nTPM]":"13.2","Tissue RNA - tongue [nTPM]":"15.0","Tissue RNA - tonsil [nTPM]":"13.3","Tissue RNA - urinary bladder [nTPM]":"16.1","Tissue RNA - vagina [nTPM]":"19.9","Tissue RNA - white matter [nTPM]":"9.4","Cell RNA - A-431 [nTPM]":"42.8","Cell RNA - A549 [nTPM]":"5.9","Cell RNA - AF22 [nTPM]":"19.4","Cell RNA - AN3-CA [nTPM]":"30.6","Cell RNA - ASC diff [nTPM]":"6.4","Cell RNA - ASC TERT1 [nTPM]":"24.4","Cell RNA - BEWO [nTPM]":"169.5","Cell RNA - BJ [nTPM]":"30.9","Cell RNA - BJ hTERT+ [nTPM]":"37.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"46.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"42.9","Cell RNA - CACO-2 [nTPM]":"62.2","Cell RNA - CAPAN-2 [nTPM]":"64.5","Cell RNA - Daudi [nTPM]":"3.7","Cell RNA - EFO-21 [nTPM]":"36.4","Cell RNA - fHDF\/TERT166 [nTPM]":"36.8","Cell RNA - GAMG [nTPM]":"34.2","Cell RNA - HaCaT [nTPM]":"65.3","Cell RNA - HAP1 [nTPM]":"10.8","Cell RNA - HBEC3-KT [nTPM]":"31.3","Cell RNA - HBF TERT88 [nTPM]":"40.6","Cell RNA - HDLM-2 [nTPM]":"9.0","Cell RNA - HEK 293 [nTPM]":"3.1","Cell RNA - HEL [nTPM]":"8.6","Cell RNA - HeLa [nTPM]":"21.4","Cell RNA - Hep G2 [nTPM]":"25.9","Cell RNA - HHSteC [nTPM]":"32.8","Cell RNA - HL-60 [nTPM]":"17.9","Cell RNA - HMC-1 [nTPM]":"33.8","Cell RNA - HSkMC [nTPM]":"7.1","Cell RNA - hTCEpi [nTPM]":"61.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.8","Cell RNA - hTERT-HME1 [nTPM]":"46.0","Cell RNA - hTERT-RPE1 [nTPM]":"24.5","Cell RNA - HUVEC TERT2 [nTPM]":"32.5","Cell RNA - JURKAT [nTPM]":"22.3","Cell RNA - K-562 [nTPM]":"16.3","Cell RNA - Karpas-707 [nTPM]":"16.1","Cell RNA - LHCN-M2 [nTPM]":"13.3","Cell RNA - MCF7 [nTPM]":"33.3","Cell RNA - MOLT-4 [nTPM]":"9.4","Cell RNA - NB-4 [nTPM]":"51.7","Cell RNA - NTERA-2 [nTPM]":"20.7","Cell RNA - OE19 [nTPM]":"2.8","Cell RNA - PC-3 [nTPM]":"25.4","Cell RNA - REH [nTPM]":"12.3","Cell RNA - RH-30 [nTPM]":"0.7","Cell RNA - RPMI-8226 [nTPM]":"27.1","Cell RNA - RPTEC TERT1 [nTPM]":"42.6","Cell RNA - RT4 [nTPM]":"25.4","Cell RNA - SCLC-21H [nTPM]":"8.6","Cell RNA - SH-SY5Y [nTPM]":"17.5","Cell RNA - SiHa [nTPM]":"11.6","Cell RNA - SK-BR-3 [nTPM]":"50.4","Cell RNA - SK-MEL-30 [nTPM]":"42.4","Cell RNA - SuSa [nTPM]":"28.1","Cell RNA - T-47d [nTPM]":"44.9","Cell RNA - THP-1 [nTPM]":"39.3","Cell RNA - TIME [nTPM]":"7.4","Cell RNA - U-138 MG [nTPM]":"17.1","Cell RNA - U-2 OS [nTPM]":"27.4","Cell RNA - U-2197 [nTPM]":"33.1","Cell RNA - U-251 MG [nTPM]":"18.2","Cell RNA - U-266\/70 [nTPM]":"14.4","Cell RNA - U-266\/84 [nTPM]":"30.4","Cell RNA - U-698 [nTPM]":"16.5","Cell RNA - U-87 MG [nTPM]":"31.4","Cell RNA - U-937 [nTPM]":"10.2","Cell RNA - WM-115 [nTPM]":"15.5","Blood RNA - basophil [nTPM]":"27.9","Blood RNA - classical monocyte [nTPM]":"7.9","Blood RNA - eosinophil [nTPM]":"16.2","Blood RNA - gdT-cell [nTPM]":"5.3","Blood RNA - intermediate monocyte [nTPM]":"8.9","Blood RNA - MAIT T-cell [nTPM]":"7.9","Blood RNA - memory B-cell [nTPM]":"10.6","Blood RNA - memory CD4 T-cell [nTPM]":"7.8","Blood RNA - memory CD8 T-cell [nTPM]":"10.6","Blood RNA - myeloid DC [nTPM]":"7.3","Blood RNA - naive B-cell [nTPM]":"14.5","Blood RNA - naive CD4 T-cell [nTPM]":"5.9","Blood RNA - naive CD8 T-cell [nTPM]":"6.4","Blood RNA - neutrophil [nTPM]":"8.2","Blood RNA - NK-cell [nTPM]":"8.6","Blood RNA - non-classical monocyte [nTPM]":"4.7","Blood RNA - plasmacytoid DC [nTPM]":"8.9","Blood RNA - T-reg [nTPM]":"10.5","Blood RNA - total PBMC [nTPM]":"6.1","Brain RNA - amygdala [nTPM]":"9.4","Brain RNA - basal ganglia [nTPM]":"10.2","Brain RNA - cerebellum [nTPM]":"10.9","Brain RNA - cerebral cortex [nTPM]":"12.9","Brain RNA - hippocampal formation [nTPM]":"9.5","Brain RNA - hypothalamus [nTPM]":"10.5","Brain RNA - medulla oblongata [nTPM]":"9.7","Brain RNA - midbrain [nTPM]":"9.7","Brain RNA - pons [nTPM]":"9.8","Brain RNA - spinal cord [nTPM]":"9.8","Brain RNA - thalamus [nTPM]":"10.0","Brain RNA - white matter [nTPM]":"9.4","Single Cell Type RNA - Adipocytes [nTPM]":"12.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.2","Single Cell Type RNA - Astrocytes [nTPM]":"10.7","Single Cell Type RNA - B-cells [nTPM]":"7.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"57.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"21.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"32.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.4","Single Cell Type RNA - Bipolar cells [nTPM]":"6.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"20.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"121.0","Single Cell Type RNA - dendritic cells [nTPM]":"11.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"27.8","Single Cell Type RNA - Early spermatids [nTPM]":"26.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"33.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.7","Single Cell Type RNA - Endothelial cells [nTPM]":"11.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"9.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"17.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"21.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"343.6","Single Cell Type RNA - Fibroblasts [nTPM]":"13.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"27.2","Single Cell Type RNA - granulocytes [nTPM]":"15.8","Single Cell Type RNA - Granulosa cells [nTPM]":"7.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.1","Single Cell Type RNA - Hepatocytes [nTPM]":"6.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.0","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"13.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.3","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"8.5","Single Cell Type RNA - Langerhans cells [nTPM]":"6.0","Single Cell Type RNA - Late spermatids [nTPM]":"7.9","Single Cell Type RNA - Leydig cells [nTPM]":"7.5","Single Cell Type RNA - Macrophages [nTPM]":"8.5","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"11.6","Single Cell Type RNA - Muller glia cells [nTPM]":"10.4","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"11.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"29.3","Single Cell Type RNA - Paneth cells [nTPM]":"16.2","Single Cell Type RNA - Peritubular cells [nTPM]":"7.2","Single Cell Type RNA - Plasma cells [nTPM]":"5.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"28.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"12.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"29.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"42.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"8.7","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.5","Single Cell Type RNA - Spermatocytes [nTPM]":"70.1","Single Cell Type RNA - Spermatogonia [nTPM]":"18.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"41.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"64.6","Single Cell Type RNA - T-cells [nTPM]":"11.4","Single Cell Type RNA - Theca cells [nTPM]":"6.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.2","Single Cell Type RNA - Urothelial cells [nTPM]":"29.8"},{"Gene":"CFAP36","Gene synonym":["BARTL1","CCDC104","MGC15407"],"Ensembl":"ENSG00000163001","Gene description":"Cilia and flagella associated protein 36","Uniprot":["Q96G28"],"Chromosome":"2","Position":"55519604-55545079","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"1342.4","Late spermatids":"262.5","Spermatocytes":"346.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008994","HPA017061"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center","Nuclear bodies","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 29: Early spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Nucleoli fibrillar center","Nuclear bodies"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA008994":"AB_2275429","HPA017061":"AB_1846129"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.65e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.57e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.96e-1"},"Tissue RNA - adipose tissue [nTPM]":"39.1","Tissue RNA - adrenal gland [nTPM]":"42.7","Tissue RNA - amygdala [nTPM]":"72.7","Tissue RNA - appendix [nTPM]":"20.2","Tissue RNA - basal ganglia [nTPM]":"74.8","Tissue RNA - bone marrow [nTPM]":"16.5","Tissue RNA - breast [nTPM]":"48.9","Tissue RNA - cerebellum [nTPM]":"61.8","Tissue RNA - cerebral cortex [nTPM]":"98.8","Tissue RNA - cervix [nTPM]":"49.8","Tissue RNA - choroid plexus [nTPM]":"82.8","Tissue RNA - colon [nTPM]":"52.3","Tissue RNA - duodenum [nTPM]":"15.1","Tissue RNA - endometrium 1 [nTPM]":"47.1","Tissue RNA - epididymis [nTPM]":"77.0","Tissue RNA - esophagus [nTPM]":"21.9","Tissue RNA - fallopian tube [nTPM]":"62.3","Tissue RNA - gallbladder [nTPM]":"40.9","Tissue RNA - heart muscle [nTPM]":"35.7","Tissue RNA - hippocampal formation [nTPM]":"75.0","Tissue RNA - hypothalamus [nTPM]":"78.5","Tissue RNA - kidney [nTPM]":"63.2","Tissue RNA - liver [nTPM]":"17.7","Tissue RNA - lung [nTPM]":"33.9","Tissue RNA - lymph node [nTPM]":"21.7","Tissue RNA - medulla oblongata [nTPM]":"71.8","Tissue RNA - midbrain [nTPM]":"70.4","Tissue RNA - ovary [nTPM]":"58.9","Tissue RNA - pancreas [nTPM]":"33.6","Tissue RNA - parathyroid gland [nTPM]":"78.0","Tissue RNA - pituitary gland [nTPM]":"106.7","Tissue RNA - placenta [nTPM]":"20.6","Tissue RNA - pons [nTPM]":"72.1","Tissue RNA - prostate [nTPM]":"41.6","Tissue RNA - rectum [nTPM]":"23.2","Tissue RNA - retina [nTPM]":"124.3","Tissue RNA - salivary gland [nTPM]":"28.7","Tissue RNA - seminal vesicle [nTPM]":"45.0","Tissue RNA - skeletal muscle [nTPM]":"19.2","Tissue RNA - skin 1 [nTPM]":"18.8","Tissue RNA - small intestine [nTPM]":"25.2","Tissue RNA - smooth muscle [nTPM]":"37.4","Tissue RNA - spinal cord [nTPM]":"65.9","Tissue RNA - spleen [nTPM]":"18.2","Tissue RNA - stomach 1 [nTPM]":"42.1","Tissue RNA - testis [nTPM]":"145.2","Tissue RNA - thalamus [nTPM]":"73.6","Tissue RNA - thymus [nTPM]":"22.8","Tissue RNA - thyroid gland [nTPM]":"78.0","Tissue RNA - tongue [nTPM]":"27.1","Tissue RNA - tonsil [nTPM]":"19.7","Tissue RNA - urinary bladder [nTPM]":"40.7","Tissue RNA - vagina [nTPM]":"33.6","Tissue RNA - white matter [nTPM]":"70.1","Cell RNA - A-431 [nTPM]":"59.5","Cell RNA - A549 [nTPM]":"47.3","Cell RNA - AF22 [nTPM]":"50.2","Cell RNA - AN3-CA [nTPM]":"66.3","Cell RNA - ASC diff [nTPM]":"64.4","Cell RNA - ASC TERT1 [nTPM]":"119.4","Cell RNA - BEWO [nTPM]":"30.4","Cell RNA - BJ [nTPM]":"36.6","Cell RNA - BJ hTERT+ [nTPM]":"73.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"54.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"46.6","Cell RNA - CACO-2 [nTPM]":"34.6","Cell RNA - CAPAN-2 [nTPM]":"21.2","Cell RNA - Daudi [nTPM]":"21.3","Cell RNA - EFO-21 [nTPM]":"82.3","Cell RNA - fHDF\/TERT166 [nTPM]":"48.9","Cell RNA - GAMG [nTPM]":"81.9","Cell RNA - HaCaT [nTPM]":"38.4","Cell RNA - HAP1 [nTPM]":"39.3","Cell RNA - HBEC3-KT [nTPM]":"51.4","Cell RNA - HBF TERT88 [nTPM]":"67.7","Cell RNA - HDLM-2 [nTPM]":"51.9","Cell RNA - HEK 293 [nTPM]":"76.2","Cell RNA - HEL [nTPM]":"31.0","Cell RNA - HeLa [nTPM]":"43.9","Cell RNA - Hep G2 [nTPM]":"38.1","Cell RNA - HHSteC [nTPM]":"70.0","Cell RNA - HL-60 [nTPM]":"59.4","Cell RNA - HMC-1 [nTPM]":"38.4","Cell RNA - HSkMC [nTPM]":"58.1","Cell RNA - hTCEpi [nTPM]":"82.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"74.0","Cell RNA - hTERT-HME1 [nTPM]":"92.1","Cell RNA - hTERT-RPE1 [nTPM]":"146.8","Cell RNA - HUVEC TERT2 [nTPM]":"58.9","Cell RNA - JURKAT [nTPM]":"42.5","Cell RNA - K-562 [nTPM]":"40.1","Cell RNA - Karpas-707 [nTPM]":"18.2","Cell RNA - LHCN-M2 [nTPM]":"66.1","Cell RNA - MCF7 [nTPM]":"44.4","Cell RNA - MOLT-4 [nTPM]":"35.7","Cell RNA - NB-4 [nTPM]":"67.5","Cell RNA - NTERA-2 [nTPM]":"25.2","Cell RNA - OE19 [nTPM]":"38.7","Cell RNA - PC-3 [nTPM]":"44.8","Cell RNA - REH [nTPM]":"27.2","Cell RNA - RH-30 [nTPM]":"59.7","Cell RNA - RPMI-8226 [nTPM]":"21.7","Cell RNA - RPTEC TERT1 [nTPM]":"112.1","Cell RNA - RT4 [nTPM]":"33.7","Cell RNA - SCLC-21H [nTPM]":"74.1","Cell RNA - SH-SY5Y [nTPM]":"36.6","Cell RNA - SiHa [nTPM]":"49.4","Cell RNA - SK-BR-3 [nTPM]":"25.6","Cell RNA - SK-MEL-30 [nTPM]":"68.5","Cell RNA - SuSa [nTPM]":"26.2","Cell RNA - T-47d [nTPM]":"42.1","Cell RNA - THP-1 [nTPM]":"19.7","Cell RNA - TIME [nTPM]":"32.5","Cell RNA - U-138 MG [nTPM]":"57.6","Cell RNA - U-2 OS [nTPM]":"33.7","Cell RNA - U-2197 [nTPM]":"58.5","Cell RNA - U-251 MG [nTPM]":"50.8","Cell RNA - U-266\/70 [nTPM]":"29.9","Cell RNA - U-266\/84 [nTPM]":"14.2","Cell RNA - U-698 [nTPM]":"7.3","Cell RNA - U-87 MG [nTPM]":"94.0","Cell RNA - U-937 [nTPM]":"26.7","Cell RNA - WM-115 [nTPM]":"26.8","Blood RNA - basophil [nTPM]":"15.5","Blood RNA - classical monocyte [nTPM]":"4.3","Blood RNA - eosinophil [nTPM]":"13.6","Blood RNA - gdT-cell [nTPM]":"18.3","Blood RNA - intermediate monocyte [nTPM]":"5.0","Blood RNA - MAIT T-cell [nTPM]":"35.4","Blood RNA - memory B-cell [nTPM]":"16.9","Blood RNA - memory CD4 T-cell [nTPM]":"50.6","Blood RNA - memory CD8 T-cell [nTPM]":"29.6","Blood RNA - myeloid DC [nTPM]":"5.8","Blood RNA - naive B-cell [nTPM]":"11.7","Blood RNA - naive CD4 T-cell [nTPM]":"41.1","Blood RNA - naive CD8 T-cell [nTPM]":"26.0","Blood RNA - neutrophil [nTPM]":"5.2","Blood RNA - NK-cell [nTPM]":"12.3","Blood RNA - non-classical monocyte [nTPM]":"6.4","Blood RNA - plasmacytoid DC [nTPM]":"13.5","Blood RNA - T-reg [nTPM]":"30.5","Blood RNA - total PBMC [nTPM]":"15.9","Brain RNA - amygdala [nTPM]":"72.7","Brain RNA - basal ganglia [nTPM]":"74.8","Brain RNA - cerebellum [nTPM]":"61.8","Brain RNA - cerebral cortex [nTPM]":"98.8","Brain RNA - hippocampal formation [nTPM]":"75.0","Brain RNA - hypothalamus [nTPM]":"78.5","Brain RNA - medulla oblongata [nTPM]":"71.8","Brain RNA - midbrain [nTPM]":"70.4","Brain RNA - pons [nTPM]":"72.1","Brain RNA - spinal cord [nTPM]":"65.9","Brain RNA - thalamus [nTPM]":"73.6","Brain RNA - white matter [nTPM]":"70.1","Single Cell Type RNA - Adipocytes [nTPM]":"51.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"30.6","Single Cell Type RNA - Astrocytes [nTPM]":"15.7","Single Cell Type RNA - B-cells [nTPM]":"14.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"52.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"22.2","Single Cell Type RNA - Bipolar cells [nTPM]":"39.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"48.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"77.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"37.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"38.6","Single Cell Type RNA - Club cells [nTPM]":"27.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"35.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.3","Single Cell Type RNA - dendritic cells [nTPM]":"14.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"92.0","Single Cell Type RNA - Ductal cells [nTPM]":"61.9","Single Cell Type RNA - Early spermatids [nTPM]":"1342.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"184.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"51.8","Single Cell Type RNA - Endothelial cells [nTPM]":"42.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"17.0","Single Cell Type RNA - Erythroid cells [nTPM]":"21.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"51.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"60.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"27.0","Single Cell Type RNA - Fibroblasts [nTPM]":"44.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"36.3","Single Cell Type RNA - granulocytes [nTPM]":"39.1","Single Cell Type RNA - Granulosa cells [nTPM]":"27.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"42.1","Single Cell Type RNA - Hepatocytes [nTPM]":"10.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"23.6","Single Cell Type RNA - Horizontal cells [nTPM]":"23.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"41.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"8.7","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"262.5","Single Cell Type RNA - Leydig cells [nTPM]":"75.2","Single Cell Type RNA - Macrophages [nTPM]":"12.8","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"16.9","Single Cell Type RNA - Muller glia cells [nTPM]":"145.0","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"13.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"37.0","Single Cell Type RNA - Paneth cells [nTPM]":"11.5","Single Cell Type RNA - Peritubular cells [nTPM]":"67.7","Single Cell Type RNA - Plasma cells [nTPM]":"11.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"41.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"146.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"99.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"92.4","Single Cell Type RNA - Sertoli cells [nTPM]":"59.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"43.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"43.4","Single Cell Type RNA - Spermatocytes [nTPM]":"346.0","Single Cell Type RNA - Spermatogonia [nTPM]":"29.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.8","Single Cell Type RNA - T-cells [nTPM]":"24.7","Single Cell Type RNA - Theca cells [nTPM]":"36.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.9","Single Cell Type RNA - Urothelial cells [nTPM]":"35.6"},{"Gene":"CTSV","Gene synonym":["CTSL2","CTSU"],"Ensembl":"ENSG00000136943","Gene description":"Cathepsin V","Uniprot":["O60911"],"Chromosome":"9","Position":"97029677-97156556","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protease","Thiol protease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"lymphoid tissue":"643.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"63.7","Cytotrophoblasts":"122.3","Extravillous trophoblasts":"153.0","Granulosa cells":"54.2","Syncytiotrophoblasts":"67.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"plasmacytoid DC":"15.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"15.1"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"BEWO":"592.6","SuSa":"739.0"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017112"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center","Plasma membrane","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"370000","Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 63: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 38: Extravillous trophoblasts - Unknown function","Subcellular main location":["Nucleoli fibrillar center","Cytosol"],"Subcellular additional location":["Nucleoplasm","Plasma membrane"],"Antibody RRID":{"CAB017112":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.41e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.83e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.04e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.87e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.39e-4"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"0.6","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"0.7","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"5.8","Tissue RNA - cerebellum [nTPM]":"0.8","Tissue RNA - cerebral cortex [nTPM]":"1.6","Tissue RNA - cervix [nTPM]":"43.1","Tissue RNA - choroid plexus [nTPM]":"0.8","Tissue RNA - colon [nTPM]":"2.9","Tissue RNA - duodenum [nTPM]":"1.1","Tissue RNA - endometrium 1 [nTPM]":"2.8","Tissue RNA - epididymis [nTPM]":"1.7","Tissue RNA - esophagus [nTPM]":"19.8","Tissue RNA - fallopian tube [nTPM]":"1.3","Tissue RNA - gallbladder [nTPM]":"0.5","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.6","Tissue RNA - hypothalamus [nTPM]":"0.5","Tissue RNA - kidney [nTPM]":"21.3","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.9","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.7","Tissue RNA - midbrain [nTPM]":"0.6","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"2.1","Tissue RNA - parathyroid gland [nTPM]":"1.4","Tissue RNA - pituitary gland [nTPM]":"1.5","Tissue RNA - placenta [nTPM]":"16.8","Tissue RNA - pons [nTPM]":"0.6","Tissue RNA - prostate [nTPM]":"0.7","Tissue RNA - rectum [nTPM]":"3.2","Tissue RNA - retina [nTPM]":"17.2","Tissue RNA - salivary gland [nTPM]":"9.4","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.7","Tissue RNA - skin 1 [nTPM]":"52.5","Tissue RNA - small intestine [nTPM]":"0.4","Tissue RNA - smooth muscle [nTPM]":"0.8","Tissue RNA - spinal cord [nTPM]":"0.5","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"2.8","Tissue RNA - testis [nTPM]":"65.8","Tissue RNA - thalamus [nTPM]":"0.6","Tissue RNA - thymus [nTPM]":"643.6","Tissue RNA - thyroid gland [nTPM]":"1.3","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"6.0","Tissue RNA - urinary bladder [nTPM]":"0.4","Tissue RNA - vagina [nTPM]":"20.1","Tissue RNA - white matter [nTPM]":"1.0","Cell RNA - A-431 [nTPM]":"37.1","Cell RNA - A549 [nTPM]":"5.2","Cell RNA - AF22 [nTPM]":"12.1","Cell RNA - AN3-CA [nTPM]":"33.1","Cell RNA - ASC diff [nTPM]":"0.6","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"592.6","Cell RNA - BJ [nTPM]":"0.5","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.7","Cell RNA - CACO-2 [nTPM]":"81.0","Cell RNA - CAPAN-2 [nTPM]":"37.7","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"2.8","Cell RNA - fHDF\/TERT166 [nTPM]":"0.5","Cell RNA - GAMG [nTPM]":"50.5","Cell RNA - HaCaT [nTPM]":"67.2","Cell RNA - HAP1 [nTPM]":"58.8","Cell RNA - HBEC3-KT [nTPM]":"43.9","Cell RNA - HBF TERT88 [nTPM]":"9.7","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"4.4","Cell RNA - HEL [nTPM]":"0.8","Cell RNA - HeLa [nTPM]":"1.9","Cell RNA - Hep G2 [nTPM]":"3.1","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"3.3","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"9.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.5","Cell RNA - hTERT-HME1 [nTPM]":"0.8","Cell RNA - hTERT-RPE1 [nTPM]":"0.9","Cell RNA - HUVEC TERT2 [nTPM]":"2.4","Cell RNA - JURKAT [nTPM]":"8.5","Cell RNA - K-562 [nTPM]":"0.5","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"14.4","Cell RNA - MCF7 [nTPM]":"15.2","Cell RNA - MOLT-4 [nTPM]":"0.9","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"76.2","Cell RNA - OE19 [nTPM]":"78.9","Cell RNA - PC-3 [nTPM]":"10.7","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"27.3","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"11.4","Cell RNA - RT4 [nTPM]":"3.7","Cell RNA - SCLC-21H [nTPM]":"2.4","Cell RNA - SH-SY5Y [nTPM]":"3.6","Cell RNA - SiHa [nTPM]":"39.1","Cell RNA - SK-BR-3 [nTPM]":"13.1","Cell RNA - SK-MEL-30 [nTPM]":"13.2","Cell RNA - SuSa [nTPM]":"739.0","Cell RNA - T-47d [nTPM]":"21.1","Cell RNA - THP-1 [nTPM]":"3.2","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"1.0","Cell RNA - U-2 OS [nTPM]":"23.6","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"3.5","Cell RNA - U-266\/70 [nTPM]":"5.7","Cell RNA - U-266\/84 [nTPM]":"20.6","Cell RNA - U-698 [nTPM]":"0.8","Cell RNA - U-87 MG [nTPM]":"1.6","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"4.4","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"1.8","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"3.3","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"15.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"0.6","Brain RNA - basal ganglia [nTPM]":"0.7","Brain RNA - cerebellum [nTPM]":"0.8","Brain RNA - cerebral cortex [nTPM]":"1.6","Brain RNA - hippocampal formation [nTPM]":"0.6","Brain RNA - hypothalamus [nTPM]":"0.5","Brain RNA - medulla oblongata [nTPM]":"0.7","Brain RNA - midbrain [nTPM]":"0.6","Brain RNA - pons [nTPM]":"0.6","Brain RNA - spinal cord [nTPM]":"0.5","Brain RNA - thalamus [nTPM]":"0.6","Brain RNA - white matter [nTPM]":"1.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"30.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"63.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.9","Single Cell Type RNA - Bipolar cells [nTPM]":"4.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"17.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"122.3","Single Cell Type RNA - dendritic cells [nTPM]":"6.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.8","Single Cell Type RNA - Early spermatids [nTPM]":"2.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.9","Single Cell Type RNA - Endothelial cells [nTPM]":"1.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"153.0","Single Cell Type RNA - Fibroblasts [nTPM]":"3.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"24.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"54.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.5","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"3.0","Single Cell Type RNA - Late spermatids [nTPM]":"8.2","Single Cell Type RNA - Leydig cells [nTPM]":"4.1","Single Cell Type RNA - Macrophages [nTPM]":"2.4","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.2","Single Cell Type RNA - Muller glia cells [nTPM]":"6.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.5","Single Cell Type RNA - Paneth cells [nTPM]":"10.5","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"22.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"36.6","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.6","Single Cell Type RNA - Spermatocytes [nTPM]":"46.7","Single Cell Type RNA - Spermatogonia [nTPM]":"33.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"67.3","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"0.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.2","Single Cell Type RNA - Urothelial cells [nTPM]":"8.4"},{"Gene":"DSN1","Gene synonym":["C20orf172","dJ469A13.2","hKNL-3","KNL3","MIS13"],"Ensembl":"ENSG00000149636","Gene description":"DSN1 component of MIS12 kinetochore complex","Uniprot":["Q9H410"],"Chromosome":"20","Position":"36751791-36773818","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Chromosome partition","Mitosis"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"49.8","Spermatocytes":"115.5","Spermatogonia":"75.1","Syncytiotrophoblasts":"47.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002813","HPA030627"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center","Nuclear bodies","Kinetochore","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli fibrillar center","Nuclear bodies","Kinetochore","Cytosol"],"Antibody RRID":{"HPA002813":"AB_1078343","HPA030627":"AB_2732460"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.49e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.16e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.93e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.54e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.92e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Tissue RNA - adipose tissue [nTPM]":"5.9","Tissue RNA - adrenal gland [nTPM]":"9.9","Tissue RNA - amygdala [nTPM]":"4.2","Tissue RNA - appendix [nTPM]":"7.5","Tissue RNA - basal ganglia [nTPM]":"4.2","Tissue RNA - bone marrow [nTPM]":"14.3","Tissue RNA - breast [nTPM]":"8.6","Tissue RNA - cerebellum [nTPM]":"3.9","Tissue RNA - cerebral cortex [nTPM]":"4.5","Tissue RNA - cervix [nTPM]":"5.0","Tissue RNA - choroid plexus [nTPM]":"5.2","Tissue RNA - colon [nTPM]":"9.2","Tissue RNA - duodenum [nTPM]":"6.8","Tissue RNA - endometrium 1 [nTPM]":"4.4","Tissue RNA - epididymis [nTPM]":"9.3","Tissue RNA - esophagus [nTPM]":"7.9","Tissue RNA - fallopian tube [nTPM]":"4.1","Tissue RNA - gallbladder [nTPM]":"4.4","Tissue RNA - heart muscle [nTPM]":"5.1","Tissue RNA - hippocampal formation [nTPM]":"4.3","Tissue RNA - hypothalamus [nTPM]":"4.4","Tissue RNA - kidney [nTPM]":"4.8","Tissue RNA - liver [nTPM]":"9.1","Tissue RNA - lung [nTPM]":"6.3","Tissue RNA - lymph node [nTPM]":"12.8","Tissue RNA - medulla oblongata [nTPM]":"4.0","Tissue RNA - midbrain [nTPM]":"3.9","Tissue RNA - ovary [nTPM]":"4.3","Tissue RNA - pancreas [nTPM]":"4.3","Tissue RNA - parathyroid gland [nTPM]":"5.5","Tissue RNA - pituitary gland [nTPM]":"3.5","Tissue RNA - placenta [nTPM]":"8.8","Tissue RNA - pons [nTPM]":"4.1","Tissue RNA - prostate [nTPM]":"6.5","Tissue RNA - rectum [nTPM]":"10.8","Tissue RNA - retina [nTPM]":"10.7","Tissue RNA - salivary gland [nTPM]":"5.9","Tissue RNA - seminal vesicle [nTPM]":"6.3","Tissue RNA - skeletal muscle [nTPM]":"4.0","Tissue RNA - skin 1 [nTPM]":"8.0","Tissue RNA - small intestine [nTPM]":"7.8","Tissue RNA - smooth muscle [nTPM]":"6.3","Tissue RNA - spinal cord [nTPM]":"3.9","Tissue RNA - spleen [nTPM]":"9.6","Tissue RNA - stomach 1 [nTPM]":"7.3","Tissue RNA - testis [nTPM]":"23.3","Tissue RNA - thalamus [nTPM]":"4.1","Tissue RNA - thymus [nTPM]":"16.4","Tissue RNA - thyroid gland [nTPM]":"5.1","Tissue RNA - tongue [nTPM]":"4.8","Tissue RNA - tonsil [nTPM]":"14.3","Tissue RNA - urinary bladder [nTPM]":"4.4","Tissue RNA - vagina [nTPM]":"4.7","Tissue RNA - white matter [nTPM]":"4.7","Cell RNA - A-431 [nTPM]":"36.7","Cell RNA - A549 [nTPM]":"29.1","Cell RNA - AF22 [nTPM]":"35.7","Cell RNA - AN3-CA [nTPM]":"29.5","Cell RNA - ASC diff [nTPM]":"14.0","Cell RNA - ASC TERT1 [nTPM]":"18.0","Cell RNA - BEWO [nTPM]":"24.7","Cell RNA - BJ [nTPM]":"42.9","Cell RNA - BJ hTERT+ [nTPM]":"35.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"63.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"70.2","Cell RNA - CACO-2 [nTPM]":"52.5","Cell RNA - CAPAN-2 [nTPM]":"44.4","Cell RNA - Daudi [nTPM]":"39.3","Cell RNA - EFO-21 [nTPM]":"27.4","Cell RNA - fHDF\/TERT166 [nTPM]":"23.0","Cell RNA - GAMG [nTPM]":"69.1","Cell RNA - HaCaT [nTPM]":"45.8","Cell RNA - HAP1 [nTPM]":"33.3","Cell RNA - HBEC3-KT [nTPM]":"32.7","Cell RNA - HBF TERT88 [nTPM]":"60.3","Cell RNA - HDLM-2 [nTPM]":"18.2","Cell RNA - HEK 293 [nTPM]":"22.7","Cell RNA - HEL [nTPM]":"78.3","Cell RNA - HeLa [nTPM]":"26.2","Cell RNA - Hep G2 [nTPM]":"36.1","Cell RNA - HHSteC [nTPM]":"3.0","Cell RNA - HL-60 [nTPM]":"46.2","Cell RNA - HMC-1 [nTPM]":"34.0","Cell RNA - HSkMC [nTPM]":"7.0","Cell RNA - hTCEpi [nTPM]":"9.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"43.7","Cell RNA - hTERT-HME1 [nTPM]":"13.8","Cell RNA - hTERT-RPE1 [nTPM]":"10.4","Cell RNA - HUVEC TERT2 [nTPM]":"31.5","Cell RNA - JURKAT [nTPM]":"42.4","Cell RNA - K-562 [nTPM]":"30.9","Cell RNA - Karpas-707 [nTPM]":"33.7","Cell RNA - LHCN-M2 [nTPM]":"41.7","Cell RNA - MCF7 [nTPM]":"25.3","Cell RNA - MOLT-4 [nTPM]":"59.2","Cell RNA - NB-4 [nTPM]":"34.5","Cell RNA - NTERA-2 [nTPM]":"16.8","Cell RNA - OE19 [nTPM]":"63.3","Cell RNA - PC-3 [nTPM]":"55.1","Cell RNA - REH [nTPM]":"46.1","Cell RNA - RH-30 [nTPM]":"109.4","Cell RNA - RPMI-8226 [nTPM]":"28.4","Cell RNA - RPTEC TERT1 [nTPM]":"16.2","Cell RNA - RT4 [nTPM]":"20.5","Cell RNA - SCLC-21H [nTPM]":"37.8","Cell RNA - SH-SY5Y [nTPM]":"16.9","Cell RNA - SiHa [nTPM]":"52.9","Cell RNA - SK-BR-3 [nTPM]":"53.7","Cell RNA - SK-MEL-30 [nTPM]":"25.8","Cell RNA - SuSa [nTPM]":"26.3","Cell RNA - T-47d [nTPM]":"55.9","Cell RNA - THP-1 [nTPM]":"30.5","Cell RNA - TIME [nTPM]":"16.4","Cell RNA - U-138 MG [nTPM]":"60.1","Cell RNA - U-2 OS [nTPM]":"35.0","Cell RNA - U-2197 [nTPM]":"56.9","Cell RNA - U-251 MG [nTPM]":"46.1","Cell RNA - U-266\/70 [nTPM]":"27.3","Cell RNA - U-266\/84 [nTPM]":"39.1","Cell RNA - U-698 [nTPM]":"46.4","Cell RNA - U-87 MG [nTPM]":"49.8","Cell RNA - U-937 [nTPM]":"40.8","Cell RNA - WM-115 [nTPM]":"42.6","Blood RNA - basophil [nTPM]":"53.4","Blood RNA - classical monocyte [nTPM]":"6.4","Blood RNA - eosinophil [nTPM]":"14.5","Blood RNA - gdT-cell [nTPM]":"7.4","Blood RNA - intermediate monocyte [nTPM]":"11.0","Blood RNA - MAIT T-cell [nTPM]":"8.4","Blood RNA - memory B-cell [nTPM]":"14.6","Blood RNA - memory CD4 T-cell [nTPM]":"8.1","Blood RNA - memory CD8 T-cell [nTPM]":"10.3","Blood RNA - myeloid DC [nTPM]":"7.1","Blood RNA - naive B-cell [nTPM]":"18.4","Blood RNA - naive CD4 T-cell [nTPM]":"10.1","Blood RNA - naive CD8 T-cell [nTPM]":"9.0","Blood RNA - neutrophil [nTPM]":"11.9","Blood RNA - NK-cell [nTPM]":"11.1","Blood RNA - non-classical monocyte [nTPM]":"10.1","Blood RNA - plasmacytoid DC [nTPM]":"46.9","Blood RNA - T-reg [nTPM]":"12.2","Blood RNA - total PBMC [nTPM]":"6.7","Brain RNA - amygdala [nTPM]":"4.2","Brain RNA - basal ganglia [nTPM]":"4.2","Brain RNA - cerebellum [nTPM]":"3.9","Brain RNA - cerebral cortex [nTPM]":"4.5","Brain RNA - hippocampal formation [nTPM]":"4.3","Brain RNA - hypothalamus [nTPM]":"4.4","Brain RNA - medulla oblongata [nTPM]":"4.0","Brain RNA - midbrain [nTPM]":"3.9","Brain RNA - pons [nTPM]":"4.1","Brain RNA - spinal cord [nTPM]":"3.9","Brain RNA - thalamus [nTPM]":"4.1","Brain RNA - white matter [nTPM]":"4.7","Single Cell Type RNA - Adipocytes [nTPM]":"6.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.4","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"10.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"8.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"8.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"49.8","Single Cell Type RNA - dendritic cells [nTPM]":"9.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.8","Single Cell Type RNA - Early spermatids [nTPM]":"10.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.9","Single Cell Type RNA - Endothelial cells [nTPM]":"8.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"22.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"30.4","Single Cell Type RNA - Fibroblasts [nTPM]":"8.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.4","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"21.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"6.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.7","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.6","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"6.3","Single Cell Type RNA - Langerhans cells [nTPM]":"4.6","Single Cell Type RNA - Late spermatids [nTPM]":"8.0","Single Cell Type RNA - Leydig cells [nTPM]":"8.7","Single Cell Type RNA - Macrophages [nTPM]":"6.7","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"7.4","Single Cell Type RNA - Muller glia cells [nTPM]":"6.0","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.1","Single Cell Type RNA - Paneth cells [nTPM]":"5.4","Single Cell Type RNA - Peritubular cells [nTPM]":"7.5","Single Cell Type RNA - Plasma cells [nTPM]":"22.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"17.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.2","Single Cell Type RNA - Spermatocytes [nTPM]":"115.5","Single Cell Type RNA - Spermatogonia [nTPM]":"75.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"47.5","Single Cell Type RNA - T-cells [nTPM]":"7.7","Single Cell Type RNA - Theca cells [nTPM]":"6.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.6","Single Cell Type RNA - Urothelial cells [nTPM]":"11.0"},{"Gene":"ESRRA","Gene synonym":["ERR1","ERRa","ERRalpha","ESRL1","NR3B1"],"Ensembl":"ENSG00000173153","Gene description":"Estrogen related receptor alpha","Uniprot":["P11474"],"Chromosome":"11","Position":"64305497-64316743","Protein class":["Nuclear receptors","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"195.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"159.2","Hepatocytes":"266.3","Proximal enterocytes":"199.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA053785","HPA077297"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center","Microtubules","Cytokinetic bridge"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 2: Hepatocytes - Metabolism","Subcellular main location":["Nucleoplasm","Nucleoli fibrillar center","Microtubules"],"Subcellular additional location":["Cytokinetic bridge"],"Antibody RRID":{"HPA053785":"AB_2682260","HPA077297":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.24e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.34e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.38e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.20e-2"},"Tissue RNA - adipose tissue [nTPM]":"27.3","Tissue RNA - adrenal gland [nTPM]":"35.5","Tissue RNA - amygdala [nTPM]":"25.5","Tissue RNA - appendix [nTPM]":"15.8","Tissue RNA - basal ganglia [nTPM]":"29.8","Tissue RNA - bone marrow [nTPM]":"16.3","Tissue RNA - breast [nTPM]":"23.6","Tissue RNA - cerebellum [nTPM]":"36.4","Tissue RNA - cerebral cortex [nTPM]":"31.4","Tissue RNA - cervix [nTPM]":"17.5","Tissue RNA - choroid plexus [nTPM]":"33.6","Tissue RNA - colon [nTPM]":"67.6","Tissue RNA - duodenum [nTPM]":"81.8","Tissue RNA - endometrium 1 [nTPM]":"15.5","Tissue RNA - epididymis [nTPM]":"4.7","Tissue RNA - esophagus [nTPM]":"62.7","Tissue RNA - fallopian tube [nTPM]":"14.6","Tissue RNA - gallbladder [nTPM]":"10.2","Tissue RNA - heart muscle [nTPM]":"154.9","Tissue RNA - hippocampal formation [nTPM]":"23.5","Tissue RNA - hypothalamus [nTPM]":"31.6","Tissue RNA - kidney [nTPM]":"70.3","Tissue RNA - liver [nTPM]":"91.5","Tissue RNA - lung [nTPM]":"30.9","Tissue RNA - lymph node [nTPM]":"11.0","Tissue RNA - medulla oblongata [nTPM]":"30.9","Tissue RNA - midbrain [nTPM]":"31.7","Tissue RNA - ovary [nTPM]":"8.1","Tissue RNA - pancreas [nTPM]":"56.3","Tissue RNA - parathyroid gland [nTPM]":"23.9","Tissue RNA - pituitary gland [nTPM]":"15.9","Tissue RNA - placenta [nTPM]":"15.4","Tissue RNA - pons [nTPM]":"29.8","Tissue RNA - prostate [nTPM]":"26.4","Tissue RNA - rectum [nTPM]":"22.9","Tissue RNA - retina [nTPM]":"5.1","Tissue RNA - salivary gland [nTPM]":"48.5","Tissue RNA - seminal vesicle [nTPM]":"12.6","Tissue RNA - skeletal muscle [nTPM]":"195.3","Tissue RNA - skin 1 [nTPM]":"35.9","Tissue RNA - small intestine [nTPM]":"65.4","Tissue RNA - smooth muscle [nTPM]":"7.1","Tissue RNA - spinal cord [nTPM]":"26.6","Tissue RNA - spleen [nTPM]":"32.0","Tissue RNA - stomach 1 [nTPM]":"52.4","Tissue RNA - testis [nTPM]":"8.4","Tissue RNA - thalamus [nTPM]":"37.5","Tissue RNA - thymus [nTPM]":"8.4","Tissue RNA - thyroid gland [nTPM]":"28.3","Tissue RNA - tongue [nTPM]":"88.8","Tissue RNA - tonsil [nTPM]":"12.4","Tissue RNA - urinary bladder [nTPM]":"31.0","Tissue RNA - vagina [nTPM]":"28.8","Tissue RNA - white matter [nTPM]":"23.7","Cell RNA - A-431 [nTPM]":"25.9","Cell RNA - A549 [nTPM]":"40.2","Cell RNA - AF22 [nTPM]":"9.8","Cell RNA - AN3-CA [nTPM]":"23.6","Cell RNA - ASC diff [nTPM]":"13.0","Cell RNA - ASC TERT1 [nTPM]":"12.7","Cell RNA - BEWO [nTPM]":"54.2","Cell RNA - BJ [nTPM]":"25.0","Cell RNA - BJ hTERT+ [nTPM]":"11.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.0","Cell RNA - CACO-2 [nTPM]":"37.4","Cell RNA - CAPAN-2 [nTPM]":"30.3","Cell RNA - Daudi [nTPM]":"34.9","Cell RNA - EFO-21 [nTPM]":"45.1","Cell RNA - fHDF\/TERT166 [nTPM]":"12.8","Cell RNA - GAMG [nTPM]":"23.7","Cell RNA - HaCaT [nTPM]":"66.0","Cell RNA - HAP1 [nTPM]":"16.9","Cell RNA - HBEC3-KT [nTPM]":"33.0","Cell RNA - HBF TERT88 [nTPM]":"3.5","Cell RNA - HDLM-2 [nTPM]":"23.0","Cell RNA - HEK 293 [nTPM]":"21.0","Cell RNA - HEL [nTPM]":"22.9","Cell RNA - HeLa [nTPM]":"51.7","Cell RNA - Hep G2 [nTPM]":"30.1","Cell RNA - HHSteC [nTPM]":"18.0","Cell RNA - HL-60 [nTPM]":"39.3","Cell RNA - HMC-1 [nTPM]":"55.3","Cell RNA - HSkMC [nTPM]":"17.4","Cell RNA - hTCEpi [nTPM]":"49.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"20.7","Cell RNA - hTERT-HME1 [nTPM]":"27.0","Cell RNA - hTERT-RPE1 [nTPM]":"12.8","Cell RNA - HUVEC TERT2 [nTPM]":"12.8","Cell RNA - JURKAT [nTPM]":"18.1","Cell RNA - K-562 [nTPM]":"37.9","Cell RNA - Karpas-707 [nTPM]":"18.7","Cell RNA - LHCN-M2 [nTPM]":"15.3","Cell RNA - MCF7 [nTPM]":"57.9","Cell RNA - MOLT-4 [nTPM]":"19.4","Cell RNA - NB-4 [nTPM]":"55.9","Cell RNA - NTERA-2 [nTPM]":"27.9","Cell RNA - OE19 [nTPM]":"30.4","Cell RNA - PC-3 [nTPM]":"74.4","Cell RNA - REH [nTPM]":"20.4","Cell RNA - RH-30 [nTPM]":"19.7","Cell RNA - RPMI-8226 [nTPM]":"79.6","Cell RNA - RPTEC TERT1 [nTPM]":"31.1","Cell RNA - RT4 [nTPM]":"52.4","Cell RNA - SCLC-21H [nTPM]":"20.6","Cell RNA - SH-SY5Y [nTPM]":"26.2","Cell RNA - SiHa [nTPM]":"12.8","Cell RNA - SK-BR-3 [nTPM]":"81.2","Cell RNA - SK-MEL-30 [nTPM]":"83.8","Cell RNA - SuSa [nTPM]":"5.5","Cell RNA - T-47d [nTPM]":"25.8","Cell RNA - THP-1 [nTPM]":"38.2","Cell RNA - TIME [nTPM]":"28.9","Cell RNA - U-138 MG [nTPM]":"16.6","Cell RNA - U-2 OS [nTPM]":"20.4","Cell RNA - U-2197 [nTPM]":"47.4","Cell RNA - U-251 MG [nTPM]":"25.6","Cell RNA - U-266\/70 [nTPM]":"28.6","Cell RNA - U-266\/84 [nTPM]":"25.5","Cell RNA - U-698 [nTPM]":"23.6","Cell RNA - U-87 MG [nTPM]":"26.9","Cell RNA - U-937 [nTPM]":"38.2","Cell RNA - WM-115 [nTPM]":"13.4","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"2.9","Blood RNA - eosinophil [nTPM]":"4.8","Blood RNA - gdT-cell [nTPM]":"2.7","Blood RNA - intermediate monocyte [nTPM]":"5.4","Blood RNA - MAIT T-cell [nTPM]":"2.6","Blood RNA - memory B-cell [nTPM]":"1.7","Blood RNA - memory CD4 T-cell [nTPM]":"2.3","Blood RNA - memory CD8 T-cell [nTPM]":"1.9","Blood RNA - myeloid DC [nTPM]":"2.7","Blood RNA - naive B-cell [nTPM]":"2.3","Blood RNA - naive CD4 T-cell [nTPM]":"2.3","Blood RNA - naive CD8 T-cell [nTPM]":"3.3","Blood RNA - neutrophil [nTPM]":"5.3","Blood RNA - NK-cell [nTPM]":"1.8","Blood RNA - non-classical monocyte [nTPM]":"5.1","Blood RNA - plasmacytoid DC [nTPM]":"2.1","Blood RNA - T-reg [nTPM]":"3.6","Blood RNA - total PBMC [nTPM]":"1.7","Brain RNA - amygdala [nTPM]":"25.5","Brain RNA - basal ganglia [nTPM]":"29.8","Brain RNA - cerebellum [nTPM]":"36.4","Brain RNA - cerebral cortex [nTPM]":"31.4","Brain RNA - hippocampal formation [nTPM]":"23.5","Brain RNA - hypothalamus [nTPM]":"31.6","Brain RNA - medulla oblongata [nTPM]":"30.9","Brain RNA - midbrain [nTPM]":"31.7","Brain RNA - pons [nTPM]":"29.8","Brain RNA - spinal cord [nTPM]":"26.6","Brain RNA - thalamus [nTPM]":"37.5","Brain RNA - white matter [nTPM]":"23.7","Single Cell Type RNA - Adipocytes [nTPM]":"20.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"22.7","Single Cell Type RNA - Astrocytes [nTPM]":"21.2","Single Cell Type RNA - B-cells [nTPM]":"14.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"41.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"29.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.8","Single Cell Type RNA - Bipolar cells [nTPM]":"28.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"30.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"24.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"100.1","Single Cell Type RNA - Club cells [nTPM]":"21.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"103.8","Single Cell Type RNA - dendritic cells [nTPM]":"20.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"159.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"54.8","Single Cell Type RNA - Ductal cells [nTPM]":"51.3","Single Cell Type RNA - Early spermatids [nTPM]":"3.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.4","Single Cell Type RNA - Endothelial cells [nTPM]":"15.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"37.8","Single Cell Type RNA - Erythroid cells [nTPM]":"19.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"13.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"80.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"61.3","Single Cell Type RNA - Fibroblasts [nTPM]":"12.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"39.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.3","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"9.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"35.0","Single Cell Type RNA - Hepatocytes [nTPM]":"266.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"33.6","Single Cell Type RNA - Horizontal cells [nTPM]":"33.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"16.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"82.5","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"82.7","Single Cell Type RNA - Langerhans cells [nTPM]":"11.7","Single Cell Type RNA - Late spermatids [nTPM]":"1.1","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"22.2","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"28.8","Single Cell Type RNA - Muller glia cells [nTPM]":"20.1","Single Cell Type RNA - NK-cells [nTPM]":"27.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"81.1","Single Cell Type RNA - Paneth cells [nTPM]":"103.1","Single Cell Type RNA - Peritubular cells [nTPM]":"12.0","Single Cell Type RNA - Plasma cells [nTPM]":"8.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"42.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"199.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"82.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"20.4","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"21.7","Single Cell Type RNA - Spermatocytes [nTPM]":"3.5","Single Cell Type RNA - Spermatogonia [nTPM]":"7.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"26.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"134.2","Single Cell Type RNA - T-cells [nTPM]":"14.5","Single Cell Type RNA - Theca cells [nTPM]":"22.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"113.7","Single Cell Type RNA - Urothelial cells [nTPM]":"65.0"},{"Gene":"LIPA","Gene synonym":["CESD","LAL"],"Ensembl":"ENSG00000107798","Gene description":"Lipase A, lysosomal acid type","Uniprot":["P38571"],"Chromosome":"10","Position":"89213569-89414557","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid degradation","Lipid metabolism"],"Molecular function":["Hydrolase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"398.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hofbauer cells":"515.0","Kupffer cells":"714.8","Macrophages":"303.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"classical monocyte":"167.3","intermediate monocyte":"355.1","myeloid DC":"123.6","non-classical monocyte":"198.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"123.6","monocytes":"355.1"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A-431":"354.4","AN3-CA":"367.8","ASC TERT1":"450.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB034892","HPA057052"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center","Vesicles","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"280000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":["Nucleoplasm","Nucleoli fibrillar center"],"Antibody RRID":{"CAB034892":"AB_784329","HPA057052":"AB_2683322"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.71e-2"},"Tissue RNA - adipose tissue [nTPM]":"76.0","Tissue RNA - adrenal gland [nTPM]":"46.3","Tissue RNA - amygdala [nTPM]":"43.5","Tissue RNA - appendix [nTPM]":"66.7","Tissue RNA - basal ganglia [nTPM]":"65.2","Tissue RNA - bone marrow [nTPM]":"39.8","Tissue RNA - breast [nTPM]":"47.8","Tissue RNA - cerebellum [nTPM]":"64.1","Tissue RNA - cerebral cortex [nTPM]":"74.4","Tissue RNA - cervix [nTPM]":"54.0","Tissue RNA - choroid plexus [nTPM]":"39.0","Tissue RNA - colon [nTPM]":"67.7","Tissue RNA - duodenum [nTPM]":"167.6","Tissue RNA - endometrium 1 [nTPM]":"38.8","Tissue RNA - epididymis [nTPM]":"21.7","Tissue RNA - esophagus [nTPM]":"28.6","Tissue RNA - fallopian tube [nTPM]":"37.8","Tissue RNA - gallbladder [nTPM]":"83.5","Tissue RNA - heart muscle [nTPM]":"24.2","Tissue RNA - hippocampal formation [nTPM]":"43.5","Tissue RNA - hypothalamus [nTPM]":"53.1","Tissue RNA - kidney [nTPM]":"44.9","Tissue RNA - liver [nTPM]":"218.9","Tissue RNA - lung [nTPM]":"169.5","Tissue RNA - lymph node [nTPM]":"159.3","Tissue RNA - medulla oblongata [nTPM]":"74.7","Tissue RNA - midbrain [nTPM]":"55.5","Tissue RNA - ovary [nTPM]":"32.7","Tissue RNA - pancreas [nTPM]":"21.4","Tissue RNA - parathyroid gland [nTPM]":"68.9","Tissue RNA - pituitary gland [nTPM]":"12.7","Tissue RNA - placenta [nTPM]":"79.1","Tissue RNA - pons [nTPM]":"82.2","Tissue RNA - prostate [nTPM]":"30.7","Tissue RNA - rectum [nTPM]":"72.0","Tissue RNA - retina [nTPM]":"12.6","Tissue RNA - salivary gland [nTPM]":"22.5","Tissue RNA - seminal vesicle [nTPM]":"33.8","Tissue RNA - skeletal muscle [nTPM]":"11.8","Tissue RNA - skin 1 [nTPM]":"18.7","Tissue RNA - small intestine [nTPM]":"227.5","Tissue RNA - smooth muscle [nTPM]":"47.7","Tissue RNA - spinal cord [nTPM]":"65.4","Tissue RNA - spleen [nTPM]":"398.4","Tissue RNA - stomach 1 [nTPM]":"34.3","Tissue RNA - testis [nTPM]":"13.4","Tissue RNA - thalamus [nTPM]":"57.0","Tissue RNA - thymus [nTPM]":"44.5","Tissue RNA - thyroid gland [nTPM]":"31.6","Tissue RNA - tongue [nTPM]":"22.5","Tissue RNA - tonsil [nTPM]":"45.5","Tissue RNA - urinary bladder [nTPM]":"58.4","Tissue RNA - vagina [nTPM]":"19.3","Tissue RNA - white matter [nTPM]":"115.5","Cell RNA - A-431 [nTPM]":"354.4","Cell RNA - A549 [nTPM]":"49.4","Cell RNA - AF22 [nTPM]":"30.7","Cell RNA - AN3-CA [nTPM]":"367.8","Cell RNA - ASC diff [nTPM]":"343.5","Cell RNA - ASC TERT1 [nTPM]":"450.8","Cell RNA - BEWO [nTPM]":"10.0","Cell RNA - BJ [nTPM]":"171.4","Cell RNA - BJ hTERT+ [nTPM]":"194.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"65.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"121.5","Cell RNA - CACO-2 [nTPM]":"18.6","Cell RNA - CAPAN-2 [nTPM]":"176.6","Cell RNA - Daudi [nTPM]":"63.9","Cell RNA - EFO-21 [nTPM]":"34.0","Cell RNA - fHDF\/TERT166 [nTPM]":"264.4","Cell RNA - GAMG [nTPM]":"73.7","Cell RNA - HaCaT [nTPM]":"338.7","Cell RNA - HAP1 [nTPM]":"13.8","Cell RNA - HBEC3-KT [nTPM]":"92.8","Cell RNA - HBF TERT88 [nTPM]":"53.6","Cell RNA - HDLM-2 [nTPM]":"86.1","Cell RNA - HEK 293 [nTPM]":"34.7","Cell RNA - HEL [nTPM]":"25.1","Cell RNA - HeLa [nTPM]":"19.1","Cell RNA - Hep G2 [nTPM]":"81.5","Cell RNA - HHSteC [nTPM]":"87.6","Cell RNA - HL-60 [nTPM]":"48.8","Cell RNA - HMC-1 [nTPM]":"48.9","Cell RNA - HSkMC [nTPM]":"190.4","Cell RNA - hTCEpi [nTPM]":"69.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"72.9","Cell RNA - hTERT-HME1 [nTPM]":"40.6","Cell RNA - hTERT-RPE1 [nTPM]":"88.2","Cell RNA - HUVEC TERT2 [nTPM]":"14.9","Cell RNA - JURKAT [nTPM]":"45.4","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"108.5","Cell RNA - LHCN-M2 [nTPM]":"58.3","Cell RNA - MCF7 [nTPM]":"28.2","Cell RNA - MOLT-4 [nTPM]":"45.7","Cell RNA - NB-4 [nTPM]":"34.6","Cell RNA - NTERA-2 [nTPM]":"22.7","Cell RNA - OE19 [nTPM]":"62.4","Cell RNA - PC-3 [nTPM]":"60.0","Cell RNA - REH [nTPM]":"26.4","Cell RNA - RH-30 [nTPM]":"39.0","Cell RNA - RPMI-8226 [nTPM]":"60.5","Cell RNA - RPTEC TERT1 [nTPM]":"69.2","Cell RNA - RT4 [nTPM]":"50.9","Cell RNA - SCLC-21H [nTPM]":"10.5","Cell RNA - SH-SY5Y [nTPM]":"21.8","Cell RNA - SiHa [nTPM]":"41.4","Cell RNA - SK-BR-3 [nTPM]":"49.9","Cell RNA - SK-MEL-30 [nTPM]":"133.9","Cell RNA - SuSa [nTPM]":"20.4","Cell RNA - T-47d [nTPM]":"64.4","Cell RNA - THP-1 [nTPM]":"65.8","Cell RNA - TIME [nTPM]":"26.2","Cell RNA - U-138 MG [nTPM]":"58.8","Cell RNA - U-2 OS [nTPM]":"15.5","Cell RNA - U-2197 [nTPM]":"132.1","Cell RNA - U-251 MG [nTPM]":"44.6","Cell RNA - U-266\/70 [nTPM]":"60.0","Cell RNA - U-266\/84 [nTPM]":"65.7","Cell RNA - U-698 [nTPM]":"25.8","Cell RNA - U-87 MG [nTPM]":"71.4","Cell RNA - U-937 [nTPM]":"112.9","Cell RNA - WM-115 [nTPM]":"82.1","Blood RNA - basophil [nTPM]":"4.2","Blood RNA - classical monocyte [nTPM]":"167.3","Blood RNA - eosinophil [nTPM]":"16.9","Blood RNA - gdT-cell [nTPM]":"40.0","Blood RNA - intermediate monocyte [nTPM]":"355.1","Blood RNA - MAIT T-cell [nTPM]":"40.6","Blood RNA - memory B-cell [nTPM]":"31.9","Blood RNA - memory CD4 T-cell [nTPM]":"35.8","Blood RNA - memory CD8 T-cell [nTPM]":"38.8","Blood RNA - myeloid DC [nTPM]":"123.6","Blood RNA - naive B-cell [nTPM]":"33.4","Blood RNA - naive CD4 T-cell [nTPM]":"36.7","Blood RNA - naive CD8 T-cell [nTPM]":"40.4","Blood RNA - neutrophil [nTPM]":"7.1","Blood RNA - NK-cell [nTPM]":"29.8","Blood RNA - non-classical monocyte [nTPM]":"198.5","Blood RNA - plasmacytoid DC [nTPM]":"25.0","Blood RNA - T-reg [nTPM]":"38.2","Blood RNA - total PBMC [nTPM]":"159.6","Brain RNA - amygdala [nTPM]":"43.5","Brain RNA - basal ganglia [nTPM]":"65.2","Brain RNA - cerebellum [nTPM]":"64.1","Brain RNA - cerebral cortex [nTPM]":"74.4","Brain RNA - hippocampal formation [nTPM]":"43.5","Brain RNA - hypothalamus [nTPM]":"53.1","Brain RNA - medulla oblongata [nTPM]":"74.7","Brain RNA - midbrain [nTPM]":"55.5","Brain RNA - pons [nTPM]":"82.2","Brain RNA - spinal cord [nTPM]":"65.4","Brain RNA - thalamus [nTPM]":"57.0","Brain RNA - white matter [nTPM]":"115.5","Single Cell Type RNA - Adipocytes [nTPM]":"75.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"33.8","Single Cell Type RNA - Astrocytes [nTPM]":"11.1","Single Cell Type RNA - B-cells [nTPM]":"35.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"17.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"30.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"58.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"25.6","Single Cell Type RNA - Bipolar cells [nTPM]":"5.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"45.8","Single Cell Type RNA - Club cells [nTPM]":"31.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"33.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"34.8","Single Cell Type RNA - dendritic cells [nTPM]":"31.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"35.1","Single Cell Type RNA - Early spermatids [nTPM]":"6.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.4","Single Cell Type RNA - Endothelial cells [nTPM]":"56.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.8","Single Cell Type RNA - Erythroid cells [nTPM]":"27.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"34.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"36.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"32.9","Single Cell Type RNA - Fibroblasts [nTPM]":"34.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.5","Single Cell Type RNA - granulocytes [nTPM]":"28.5","Single Cell Type RNA - Granulosa cells [nTPM]":"10.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"54.7","Single Cell Type RNA - Hepatocytes [nTPM]":"66.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"515.0","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.9","Single Cell Type RNA - Ionocytes [nTPM]":"40.7","Single Cell Type RNA - Kupffer cells [nTPM]":"714.8","Single Cell Type RNA - Langerhans cells [nTPM]":"69.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.7","Single Cell Type RNA - Leydig cells [nTPM]":"11.5","Single Cell Type RNA - Macrophages [nTPM]":"303.1","Single Cell Type RNA - Melanocytes [nTPM]":"48.0","Single Cell Type RNA - Microglial cells [nTPM]":"30.0","Single Cell Type RNA - monocytes [nTPM]":"71.7","Single Cell Type RNA - Muller glia cells [nTPM]":"33.1","Single Cell Type RNA - NK-cells [nTPM]":"29.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"143.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"19.3","Single Cell Type RNA - Paneth cells [nTPM]":"12.0","Single Cell Type RNA - Peritubular cells [nTPM]":"21.8","Single Cell Type RNA - Plasma cells [nTPM]":"15.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"161.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"28.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"21.0","Single Cell Type RNA - Spermatocytes [nTPM]":"5.1","Single Cell Type RNA - Spermatogonia [nTPM]":"13.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"31.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"20.0","Single Cell Type RNA - T-cells [nTPM]":"33.1","Single Cell Type RNA - Theca cells [nTPM]":"17.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.1","Single Cell Type RNA - Urothelial cells [nTPM]":"24.0"},{"Gene":"MAP3K14","Gene synonym":["FTDCR1B","HS","HSNIK","NIK"],"Ensembl":"ENSG00000006062","Gene description":"Mitogen-activated protein kinase kinase kinase 14","Uniprot":["Q99558"],"Chromosome":"17","Position":"45263119-45317029","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"monocytes":"33.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A549":"40.6","U-251 MG":"43.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027269","HPA027270"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 9: U-2 OS - Unknown function","Single cell expression cluster":"Cluster 3: Monocytes - Immune response regulation","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":["Nucleoplasm","Nucleoli fibrillar center"],"Antibody RRID":{"HPA027269":"AB_2732436","HPA027270":"AB_2732437"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.27e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.78e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Tissue RNA - adipose tissue [nTPM]":"5.9","Tissue RNA - adrenal gland [nTPM]":"4.7","Tissue RNA - amygdala [nTPM]":"2.6","Tissue RNA - appendix [nTPM]":"12.5","Tissue RNA - basal ganglia [nTPM]":"5.0","Tissue RNA - bone marrow [nTPM]":"5.2","Tissue RNA - breast [nTPM]":"6.4","Tissue RNA - cerebellum [nTPM]":"2.9","Tissue RNA - cerebral cortex [nTPM]":"2.3","Tissue RNA - cervix [nTPM]":"7.1","Tissue RNA - choroid plexus [nTPM]":"2.8","Tissue RNA - colon [nTPM]":"15.6","Tissue RNA - duodenum [nTPM]":"8.1","Tissue RNA - endometrium 1 [nTPM]":"5.7","Tissue RNA - epididymis [nTPM]":"1.9","Tissue RNA - esophagus [nTPM]":"7.8","Tissue RNA - fallopian tube [nTPM]":"6.6","Tissue RNA - gallbladder [nTPM]":"5.9","Tissue RNA - heart muscle [nTPM]":"9.9","Tissue RNA - hippocampal formation [nTPM]":"3.2","Tissue RNA - hypothalamus [nTPM]":"2.7","Tissue RNA - kidney [nTPM]":"5.1","Tissue RNA - liver [nTPM]":"7.3","Tissue RNA - lung [nTPM]":"8.1","Tissue RNA - lymph node [nTPM]":"17.7","Tissue RNA - medulla oblongata [nTPM]":"3.6","Tissue RNA - midbrain [nTPM]":"4.6","Tissue RNA - ovary [nTPM]":"6.0","Tissue RNA - pancreas [nTPM]":"8.3","Tissue RNA - parathyroid gland [nTPM]":"4.6","Tissue RNA - pituitary gland [nTPM]":"5.9","Tissue RNA - placenta [nTPM]":"2.7","Tissue RNA - pons [nTPM]":"3.1","Tissue RNA - prostate [nTPM]":"7.0","Tissue RNA - rectum [nTPM]":"5.2","Tissue RNA - retina [nTPM]":"2.2","Tissue RNA - salivary gland [nTPM]":"8.1","Tissue RNA - seminal vesicle [nTPM]":"4.7","Tissue RNA - skeletal muscle [nTPM]":"28.0","Tissue RNA - skin 1 [nTPM]":"8.5","Tissue RNA - small intestine [nTPM]":"10.3","Tissue RNA - smooth muscle [nTPM]":"5.9","Tissue RNA - spinal cord [nTPM]":"2.5","Tissue RNA - spleen [nTPM]":"12.4","Tissue RNA - stomach 1 [nTPM]":"7.6","Tissue RNA - testis [nTPM]":"6.9","Tissue RNA - thalamus [nTPM]":"4.8","Tissue RNA - thymus [nTPM]":"13.4","Tissue RNA - thyroid gland [nTPM]":"5.8","Tissue RNA - tongue [nTPM]":"9.9","Tissue RNA - tonsil [nTPM]":"16.0","Tissue RNA - urinary bladder [nTPM]":"7.2","Tissue RNA - vagina [nTPM]":"7.1","Tissue RNA - white matter [nTPM]":"2.1","Cell RNA - A-431 [nTPM]":"17.1","Cell RNA - A549 [nTPM]":"40.6","Cell RNA - AF22 [nTPM]":"3.6","Cell RNA - AN3-CA [nTPM]":"6.5","Cell RNA - ASC diff [nTPM]":"2.4","Cell RNA - ASC TERT1 [nTPM]":"7.1","Cell RNA - BEWO [nTPM]":"9.4","Cell RNA - BJ [nTPM]":"4.5","Cell RNA - BJ hTERT+ [nTPM]":"3.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"14.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.1","Cell RNA - CACO-2 [nTPM]":"5.5","Cell RNA - CAPAN-2 [nTPM]":"21.0","Cell RNA - Daudi [nTPM]":"7.4","Cell RNA - EFO-21 [nTPM]":"24.1","Cell RNA - fHDF\/TERT166 [nTPM]":"5.3","Cell RNA - GAMG [nTPM]":"14.6","Cell RNA - HaCaT [nTPM]":"11.6","Cell RNA - HAP1 [nTPM]":"1.5","Cell RNA - HBEC3-KT [nTPM]":"6.5","Cell RNA - HBF TERT88 [nTPM]":"7.6","Cell RNA - HDLM-2 [nTPM]":"24.3","Cell RNA - HEK 293 [nTPM]":"3.1","Cell RNA - HEL [nTPM]":"1.4","Cell RNA - HeLa [nTPM]":"10.1","Cell RNA - Hep G2 [nTPM]":"2.1","Cell RNA - HHSteC [nTPM]":"7.1","Cell RNA - HL-60 [nTPM]":"1.1","Cell RNA - HMC-1 [nTPM]":"6.9","Cell RNA - HSkMC [nTPM]":"10.0","Cell RNA - hTCEpi [nTPM]":"3.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.3","Cell RNA - hTERT-HME1 [nTPM]":"3.6","Cell RNA - hTERT-RPE1 [nTPM]":"15.6","Cell RNA - HUVEC TERT2 [nTPM]":"3.0","Cell RNA - JURKAT [nTPM]":"3.2","Cell RNA - K-562 [nTPM]":"2.7","Cell RNA - Karpas-707 [nTPM]":"30.1","Cell RNA - LHCN-M2 [nTPM]":"8.1","Cell RNA - MCF7 [nTPM]":"6.1","Cell RNA - MOLT-4 [nTPM]":"6.8","Cell RNA - NB-4 [nTPM]":"1.7","Cell RNA - NTERA-2 [nTPM]":"1.8","Cell RNA - OE19 [nTPM]":"11.1","Cell RNA - PC-3 [nTPM]":"5.1","Cell RNA - REH [nTPM]":"9.5","Cell RNA - RH-30 [nTPM]":"12.1","Cell RNA - RPMI-8226 [nTPM]":"17.9","Cell RNA - RPTEC TERT1 [nTPM]":"10.5","Cell RNA - RT4 [nTPM]":"2.6","Cell RNA - SCLC-21H [nTPM]":"3.5","Cell RNA - SH-SY5Y [nTPM]":"3.0","Cell RNA - SiHa [nTPM]":"7.6","Cell RNA - SK-BR-3 [nTPM]":"3.4","Cell RNA - SK-MEL-30 [nTPM]":"5.0","Cell RNA - SuSa [nTPM]":"5.5","Cell RNA - T-47d [nTPM]":"2.8","Cell RNA - THP-1 [nTPM]":"0.4","Cell RNA - TIME [nTPM]":"5.6","Cell RNA - U-138 MG [nTPM]":"6.5","Cell RNA - U-2 OS [nTPM]":"10.2","Cell RNA - U-2197 [nTPM]":"5.7","Cell RNA - U-251 MG [nTPM]":"43.1","Cell RNA - U-266\/70 [nTPM]":"29.1","Cell RNA - U-266\/84 [nTPM]":"12.1","Cell RNA - U-698 [nTPM]":"4.1","Cell RNA - U-87 MG [nTPM]":"3.9","Cell RNA - U-937 [nTPM]":"4.0","Cell RNA - WM-115 [nTPM]":"9.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"2.0","Blood RNA - eosinophil [nTPM]":"0.8","Blood RNA - gdT-cell [nTPM]":"1.6","Blood RNA - intermediate monocyte [nTPM]":"1.8","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"4.2","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"1.0","Blood RNA - myeloid DC [nTPM]":"1.4","Blood RNA - naive B-cell [nTPM]":"4.4","Blood RNA - naive CD4 T-cell [nTPM]":"1.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.9","Blood RNA - neutrophil [nTPM]":"1.6","Blood RNA - NK-cell [nTPM]":"2.0","Blood RNA - non-classical monocyte [nTPM]":"0.6","Blood RNA - plasmacytoid DC [nTPM]":"1.7","Blood RNA - T-reg [nTPM]":"2.9","Blood RNA - total PBMC [nTPM]":"1.6","Brain RNA - amygdala [nTPM]":"2.6","Brain RNA - basal ganglia [nTPM]":"5.0","Brain RNA - cerebellum [nTPM]":"2.9","Brain RNA - cerebral cortex [nTPM]":"2.3","Brain RNA - hippocampal formation [nTPM]":"3.2","Brain RNA - hypothalamus [nTPM]":"2.7","Brain RNA - medulla oblongata [nTPM]":"3.6","Brain RNA - midbrain [nTPM]":"4.6","Brain RNA - pons [nTPM]":"3.1","Brain RNA - spinal cord [nTPM]":"2.5","Brain RNA - thalamus [nTPM]":"4.8","Brain RNA - white matter [nTPM]":"2.1","Single Cell Type RNA - Adipocytes [nTPM]":"5.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.8","Single Cell Type RNA - Astrocytes [nTPM]":"23.5","Single Cell Type RNA - B-cells [nTPM]":"15.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.8","Single Cell Type RNA - Bipolar cells [nTPM]":"4.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"2.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.9","Single Cell Type RNA - dendritic cells [nTPM]":"14.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"13.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"4.8","Single Cell Type RNA - Early spermatids [nTPM]":"4.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.0","Single Cell Type RNA - Endothelial cells [nTPM]":"6.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.5","Single Cell Type RNA - Fibroblasts [nTPM]":"6.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.6","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"2.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"9.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.9","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"9.4","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"6.2","Single Cell Type RNA - Leydig cells [nTPM]":"4.7","Single Cell Type RNA - Macrophages [nTPM]":"11.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"26.2","Single Cell Type RNA - monocytes [nTPM]":"33.4","Single Cell Type RNA - Muller glia cells [nTPM]":"1.9","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.3","Single Cell Type RNA - Paneth cells [nTPM]":"9.6","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"8.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.8","Single Cell Type RNA - Spermatocytes [nTPM]":"4.2","Single Cell Type RNA - Spermatogonia [nTPM]":"3.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"10.6","Single Cell Type RNA - Theca cells [nTPM]":"2.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.5","Single Cell Type RNA - Urothelial cells [nTPM]":"6.8"},{"Gene":"PAX5","Gene synonym":["BSAP"],"Ensembl":"ENSG00000196092","Gene description":"Paired box 5","Uniprot":["Q02548"],"Chromosome":"9","Position":"36833269-37034268","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Differentiation","Neurogenesis","Spermatogenesis","Transcription","Transcription regulation"],"Molecular function":["Developmental protein","DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"lymphoid tissue":"39.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"29","RNA single cell type specific nTPM":{"B-cells":"91.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"midbrain":"6.5"},"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"43","RNA blood cell specific nTPM":{"memory B-cell":"39.0","naive B-cell":"26.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"52","RNA blood lineage specific nTPM":{"B-cells":"39.0"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"Daudi":"66.6","REH":"194.1","U-698":"87.1"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"11","RNA mouse brain regional specific nTPM":{"midbrain":"3.9"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB026269","CAB026869","HPA056394","HPA068498"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli fibrillar center","Vesicles","Cytosol"],"Antibody RRID":{"CAB026269":null,"CAB026869":null,"HPA056394":"AB_2683116","HPA068498":"AB_2685997"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"14.9","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"9.4","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.5","Tissue RNA - cerebral cortex [nTPM]":"0.5","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.8","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.8","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.6","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"39.7","Tissue RNA - medulla oblongata [nTPM]":"1.1","Tissue RNA - midbrain [nTPM]":"6.5","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"4.1","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.8","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"1.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"3.1","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"6.6","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.8","Tissue RNA - spleen [nTPM]":"18.7","Tissue RNA - stomach 1 [nTPM]":"1.6","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"1.9","Tissue RNA - thymus [nTPM]":"2.8","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"36.2","Tissue RNA - urinary bladder [nTPM]":"1.1","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.3","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"5.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"66.6","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"3.5","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"2.2","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.5","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"1.5","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"1.9","Cell RNA - OE19 [nTPM]":"0.3","Cell RNA - PC-3 [nTPM]":"0.4","Cell RNA - REH [nTPM]":"194.1","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"13.2","Cell RNA - SH-SY5Y [nTPM]":"2.9","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.7","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"7.5","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"87.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"1.5","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"39.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"26.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"0.5","Brain RNA - cerebral cortex [nTPM]":"0.5","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.6","Brain RNA - medulla oblongata [nTPM]":"1.1","Brain RNA - midbrain [nTPM]":"6.5","Brain RNA - pons [nTPM]":"4.1","Brain RNA - spinal cord [nTPM]":"0.8","Brain RNA - thalamus [nTPM]":"1.9","Brain RNA - white matter [nTPM]":"0.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"91.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"3.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.9","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"2.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"2.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"RBFOX1","Gene synonym":["A2BP1","FOX-1","HRNBP1"],"Ensembl":"ENSG00000078328","Gene description":"RNA binding fox-1 homolog 1","Uniprot":["Q9NWB1"],"Chromosome":"16","Position":"5239802-7713340","Protein class":["Predicted intracellular proteins"],"Biological process":["mRNA processing","mRNA splicing"],"Molecular function":["RNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"brain":"73.9","heart muscle":"25.2","skeletal muscle":"95.3","tongue":"45.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Excitatory neurons":"5800.8","Inhibitory neurons":"5921.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"0.7"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"10","RNA brain regional specific nTPM":{"basal ganglia":"28.1","cerebral cortex":"73.9","hippocampal formation":"26.6","white matter":"22.6"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"15","RNA cell line specific nTPM":{"RH-30":"25.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040809","HPA066746","HPA075862"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 11: Basophils - Unknown function","Tissue expression cluster":"Cluster 47: Non-specific - Unknown function","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli fibrillar center","Golgi apparatus","Cytosol"],"Antibody RRID":{"HPA040809":"AB_10796228","HPA066746":null,"HPA075862":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-3"},"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-3"},"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.82e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"1.5","Tissue RNA - amygdala [nTPM]":"3.7","Tissue RNA - appendix [nTPM]":"0.4","Tissue RNA - basal ganglia [nTPM]":"28.1","Tissue RNA - bone marrow [nTPM]":"0.5","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"2.5","Tissue RNA - cerebral cortex [nTPM]":"73.9","Tissue RNA - cervix [nTPM]":"0.6","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.8","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"3.1","Tissue RNA - esophagus [nTPM]":"1.1","Tissue RNA - fallopian tube [nTPM]":"1.1","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"25.2","Tissue RNA - hippocampal formation [nTPM]":"26.6","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.2","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"1.1","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"1.7","Tissue RNA - rectum [nTPM]":"0.5","Tissue RNA - retina [nTPM]":"5.7","Tissue RNA - salivary gland [nTPM]":"2.2","Tissue RNA - seminal vesicle [nTPM]":"4.1","Tissue RNA - skeletal muscle [nTPM]":"95.3","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"2.7","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"1.1","Tissue RNA - thalamus [nTPM]":"2.2","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"45.3","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.4","Tissue RNA - vagina [nTPM]":"0.4","Tissue RNA - white matter [nTPM]":"22.6","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.5","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.3","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"1.6","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"1.7","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"1.6","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"25.9","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.7","Brain RNA - basal ganglia [nTPM]":"28.1","Brain RNA - cerebellum [nTPM]":"2.5","Brain RNA - cerebral cortex [nTPM]":"73.9","Brain RNA - hippocampal formation [nTPM]":"26.6","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"2.7","Brain RNA - thalamus [nTPM]":"2.2","Brain RNA - white matter [nTPM]":"22.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"97.9","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"10.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"98.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"6.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.8","Single Cell Type RNA - Endothelial cells [nTPM]":"0.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"5800.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"3.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"47.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5921.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"4.9","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"132.1","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"6.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"597.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"689.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.7","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"SEMA6C","Gene synonym":["KIAA1869"],"Ensembl":"ENSG00000143434","Gene description":"Semaphorin 6C","Uniprot":["Q9H3T2"],"Chromosome":"1","Position":"151131685-151146664","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Neurogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"skeletal muscle":"322.9","tongue":"96.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"12.9","Cardiomyocytes":"19.1","Cone photoreceptor cells":"20.9","Inhibitory neurons":"13.7","Skeletal myocytes":"12.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"14.1","HUVEC TERT2":"24.8","TIME":"11.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA076150","HPA077625"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center","Plasma membrane","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1500000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 33: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 37: Myocytes - Muscle contraction","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":["Nucleoli fibrillar center","Cytosol"],"Antibody RRID":{"HPA076150":null,"HPA077625":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.40e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.27e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.66e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.06e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.49e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Tissue RNA - adipose tissue [nTPM]":"8.8","Tissue RNA - adrenal gland [nTPM]":"2.8","Tissue RNA - amygdala [nTPM]":"7.7","Tissue RNA - appendix [nTPM]":"1.8","Tissue RNA - basal ganglia [nTPM]":"6.7","Tissue RNA - bone marrow [nTPM]":"1.2","Tissue RNA - breast [nTPM]":"7.9","Tissue RNA - cerebellum [nTPM]":"21.9","Tissue RNA - cerebral cortex [nTPM]":"9.4","Tissue RNA - cervix [nTPM]":"12.0","Tissue RNA - choroid plexus [nTPM]":"1.0","Tissue RNA - colon [nTPM]":"7.6","Tissue RNA - duodenum [nTPM]":"13.7","Tissue RNA - endometrium 1 [nTPM]":"10.5","Tissue RNA - epididymis [nTPM]":"1.4","Tissue RNA - esophagus [nTPM]":"5.5","Tissue RNA - fallopian tube [nTPM]":"10.7","Tissue RNA - gallbladder [nTPM]":"3.7","Tissue RNA - heart muscle [nTPM]":"38.8","Tissue RNA - hippocampal formation [nTPM]":"7.9","Tissue RNA - hypothalamus [nTPM]":"5.4","Tissue RNA - kidney [nTPM]":"12.1","Tissue RNA - liver [nTPM]":"12.4","Tissue RNA - lung [nTPM]":"5.1","Tissue RNA - lymph node [nTPM]":"1.7","Tissue RNA - medulla oblongata [nTPM]":"5.0","Tissue RNA - midbrain [nTPM]":"5.0","Tissue RNA - ovary [nTPM]":"14.8","Tissue RNA - pancreas [nTPM]":"3.6","Tissue RNA - parathyroid gland [nTPM]":"2.1","Tissue RNA - pituitary gland [nTPM]":"13.4","Tissue RNA - placenta [nTPM]":"1.9","Tissue RNA - pons [nTPM]":"4.9","Tissue RNA - prostate [nTPM]":"8.3","Tissue RNA - rectum [nTPM]":"1.8","Tissue RNA - retina [nTPM]":"5.2","Tissue RNA - salivary gland [nTPM]":"8.5","Tissue RNA - seminal vesicle [nTPM]":"2.3","Tissue RNA - skeletal muscle [nTPM]":"322.9","Tissue RNA - skin 1 [nTPM]":"8.9","Tissue RNA - small intestine [nTPM]":"10.8","Tissue RNA - smooth muscle [nTPM]":"6.2","Tissue RNA - spinal cord [nTPM]":"2.2","Tissue RNA - spleen [nTPM]":"3.0","Tissue RNA - stomach 1 [nTPM]":"5.4","Tissue RNA - testis [nTPM]":"32.2","Tissue RNA - thalamus [nTPM]":"7.3","Tissue RNA - thymus [nTPM]":"2.2","Tissue RNA - thyroid gland [nTPM]":"4.7","Tissue RNA - tongue [nTPM]":"96.9","Tissue RNA - tonsil [nTPM]":"0.9","Tissue RNA - urinary bladder [nTPM]":"8.4","Tissue RNA - vagina [nTPM]":"8.8","Tissue RNA - white matter [nTPM]":"5.3","Cell RNA - A-431 [nTPM]":"0.9","Cell RNA - A549 [nTPM]":"1.0","Cell RNA - AF22 [nTPM]":"14.1","Cell RNA - AN3-CA [nTPM]":"5.4","Cell RNA - ASC diff [nTPM]":"5.8","Cell RNA - ASC TERT1 [nTPM]":"1.9","Cell RNA - BEWO [nTPM]":"1.3","Cell RNA - BJ [nTPM]":"1.0","Cell RNA - BJ hTERT+ [nTPM]":"0.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.3","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"0.6","Cell RNA - Daudi [nTPM]":"0.7","Cell RNA - EFO-21 [nTPM]":"4.0","Cell RNA - fHDF\/TERT166 [nTPM]":"3.3","Cell RNA - GAMG [nTPM]":"2.0","Cell RNA - HaCaT [nTPM]":"1.4","Cell RNA - HAP1 [nTPM]":"1.3","Cell RNA - HBEC3-KT [nTPM]":"0.5","Cell RNA - HBF TERT88 [nTPM]":"0.8","Cell RNA - HDLM-2 [nTPM]":"1.3","Cell RNA - HEK 293 [nTPM]":"4.2","Cell RNA - HEL [nTPM]":"7.7","Cell RNA - HeLa [nTPM]":"0.7","Cell RNA - Hep G2 [nTPM]":"1.2","Cell RNA - HHSteC [nTPM]":"0.8","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"2.7","Cell RNA - HSkMC [nTPM]":"3.3","Cell RNA - hTCEpi [nTPM]":"1.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.2","Cell RNA - hTERT-HME1 [nTPM]":"0.6","Cell RNA - hTERT-RPE1 [nTPM]":"2.8","Cell RNA - HUVEC TERT2 [nTPM]":"24.8","Cell RNA - JURKAT [nTPM]":"4.1","Cell RNA - K-562 [nTPM]":"0.7","Cell RNA - Karpas-707 [nTPM]":"0.7","Cell RNA - LHCN-M2 [nTPM]":"2.3","Cell RNA - MCF7 [nTPM]":"0.5","Cell RNA - MOLT-4 [nTPM]":"1.3","Cell RNA - NB-4 [nTPM]":"1.0","Cell RNA - NTERA-2 [nTPM]":"6.3","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"1.7","Cell RNA - REH [nTPM]":"9.0","Cell RNA - RH-30 [nTPM]":"3.1","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.5","Cell RNA - RT4 [nTPM]":"0.4","Cell RNA - SCLC-21H [nTPM]":"7.1","Cell RNA - SH-SY5Y [nTPM]":"9.3","Cell RNA - SiHa [nTPM]":"1.3","Cell RNA - SK-BR-3 [nTPM]":"0.6","Cell RNA - SK-MEL-30 [nTPM]":"1.2","Cell RNA - SuSa [nTPM]":"3.5","Cell RNA - T-47d [nTPM]":"1.6","Cell RNA - THP-1 [nTPM]":"1.3","Cell RNA - TIME [nTPM]":"11.8","Cell RNA - U-138 MG [nTPM]":"2.3","Cell RNA - U-2 OS [nTPM]":"3.3","Cell RNA - U-2197 [nTPM]":"3.5","Cell RNA - U-251 MG [nTPM]":"0.6","Cell RNA - U-266\/70 [nTPM]":"5.9","Cell RNA - U-266\/84 [nTPM]":"1.2","Cell RNA - U-698 [nTPM]":"6.1","Cell RNA - U-87 MG [nTPM]":"0.6","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"0.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"7.7","Brain RNA - basal ganglia [nTPM]":"6.7","Brain RNA - cerebellum [nTPM]":"21.9","Brain RNA - cerebral cortex [nTPM]":"9.4","Brain RNA - hippocampal formation [nTPM]":"7.9","Brain RNA - hypothalamus [nTPM]":"5.4","Brain RNA - medulla oblongata [nTPM]":"5.0","Brain RNA - midbrain [nTPM]":"5.0","Brain RNA - pons [nTPM]":"4.9","Brain RNA - spinal cord [nTPM]":"2.2","Brain RNA - thalamus [nTPM]":"7.3","Brain RNA - white matter [nTPM]":"5.3","Single Cell Type RNA - Adipocytes [nTPM]":"12.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.8","Single Cell Type RNA - Astrocytes [nTPM]":"3.9","Single Cell Type RNA - B-cells [nTPM]":"1.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"5.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"19.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.8","Single Cell Type RNA - Endothelial cells [nTPM]":"10.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.6","Single Cell Type RNA - Fibroblasts [nTPM]":"4.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"9.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.8","Single Cell Type RNA - Hepatocytes [nTPM]":"5.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.4","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"13.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.5","Single Cell Type RNA - Langerhans cells [nTPM]":"0.7","Single Cell Type RNA - Late spermatids [nTPM]":"3.1","Single Cell Type RNA - Leydig cells [nTPM]":"5.6","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"0.4","Single Cell Type RNA - Muller glia cells [nTPM]":"1.9","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"1.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.9","Single Cell Type RNA - Spermatocytes [nTPM]":"3.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.8","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.8","Single Cell Type RNA - Urothelial cells [nTPM]":"0.5"},{"Gene":"SGMS1","Gene synonym":["MGC17342","MOB","SMS1","TMEM23"],"Ensembl":"ENSG00000198964","Gene description":"Sphingomyelin synthase 1","Uniprot":["Q86VZ5"],"Chromosome":"10","Position":"50305586-50625163","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","Lipid metabolism","Sphingolipid metabolism"],"Molecular function":["Kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"153.1","Microglial cells":"229.5","Oligodendrocyte precursor cells":"313.1","Oligodendrocytes":"422.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"K-562":"62.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045191"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli fibrillar center","Golgi apparatus","Cytosol"],"Antibody RRID":{"HPA045191":"AB_10959605"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.08e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.69e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.34e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.98e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.75e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.20e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.95e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-1"},"Tissue RNA - adipose tissue [nTPM]":"15.8","Tissue RNA - adrenal gland [nTPM]":"19.3","Tissue RNA - amygdala [nTPM]":"19.8","Tissue RNA - appendix [nTPM]":"10.7","Tissue RNA - basal ganglia [nTPM]":"27.4","Tissue RNA - bone marrow [nTPM]":"24.0","Tissue RNA - breast [nTPM]":"14.5","Tissue RNA - cerebellum [nTPM]":"21.5","Tissue RNA - cerebral cortex [nTPM]":"20.3","Tissue RNA - cervix [nTPM]":"16.9","Tissue RNA - choroid plexus [nTPM]":"33.9","Tissue RNA - colon [nTPM]":"10.1","Tissue RNA - duodenum [nTPM]":"13.5","Tissue RNA - endometrium 1 [nTPM]":"11.9","Tissue RNA - epididymis [nTPM]":"19.9","Tissue RNA - esophagus [nTPM]":"15.3","Tissue RNA - fallopian tube [nTPM]":"16.6","Tissue RNA - gallbladder [nTPM]":"15.4","Tissue RNA - heart muscle [nTPM]":"13.2","Tissue RNA - hippocampal formation [nTPM]":"17.2","Tissue RNA - hypothalamus [nTPM]":"23.0","Tissue RNA - kidney [nTPM]":"20.2","Tissue RNA - liver [nTPM]":"27.9","Tissue RNA - lung [nTPM]":"21.9","Tissue RNA - lymph node [nTPM]":"14.9","Tissue RNA - medulla oblongata [nTPM]":"29.5","Tissue RNA - midbrain [nTPM]":"24.1","Tissue RNA - ovary [nTPM]":"18.6","Tissue RNA - pancreas [nTPM]":"13.3","Tissue RNA - parathyroid gland [nTPM]":"52.9","Tissue RNA - pituitary gland [nTPM]":"6.4","Tissue RNA - placenta [nTPM]":"24.6","Tissue RNA - pons [nTPM]":"28.5","Tissue RNA - prostate [nTPM]":"19.5","Tissue RNA - rectum [nTPM]":"11.7","Tissue RNA - retina [nTPM]":"20.2","Tissue RNA - salivary gland [nTPM]":"18.0","Tissue RNA - seminal vesicle [nTPM]":"16.8","Tissue RNA - skeletal muscle [nTPM]":"9.9","Tissue RNA - skin 1 [nTPM]":"25.3","Tissue RNA - small intestine [nTPM]":"16.0","Tissue RNA - smooth muscle [nTPM]":"15.8","Tissue RNA - spinal cord [nTPM]":"23.6","Tissue RNA - spleen [nTPM]":"11.7","Tissue RNA - stomach 1 [nTPM]":"14.3","Tissue RNA - testis [nTPM]":"11.3","Tissue RNA - thalamus [nTPM]":"23.4","Tissue RNA - thymus [nTPM]":"12.0","Tissue RNA - thyroid gland [nTPM]":"24.7","Tissue RNA - tongue [nTPM]":"10.5","Tissue RNA - tonsil [nTPM]":"14.5","Tissue RNA - urinary bladder [nTPM]":"20.9","Tissue RNA - vagina [nTPM]":"13.1","Tissue RNA - white matter [nTPM]":"41.3","Cell RNA - A-431 [nTPM]":"30.2","Cell RNA - A549 [nTPM]":"14.0","Cell RNA - AF22 [nTPM]":"4.0","Cell RNA - AN3-CA [nTPM]":"9.0","Cell RNA - ASC diff [nTPM]":"14.2","Cell RNA - ASC TERT1 [nTPM]":"18.6","Cell RNA - BEWO [nTPM]":"18.8","Cell RNA - BJ [nTPM]":"19.6","Cell RNA - BJ hTERT+ [nTPM]":"19.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.6","Cell RNA - CACO-2 [nTPM]":"11.7","Cell RNA - CAPAN-2 [nTPM]":"30.3","Cell RNA - Daudi [nTPM]":"22.1","Cell RNA - EFO-21 [nTPM]":"11.3","Cell RNA - fHDF\/TERT166 [nTPM]":"25.9","Cell RNA - GAMG [nTPM]":"12.2","Cell RNA - HaCaT [nTPM]":"18.7","Cell RNA - HAP1 [nTPM]":"9.5","Cell RNA - HBEC3-KT [nTPM]":"20.6","Cell RNA - HBF TERT88 [nTPM]":"14.0","Cell RNA - HDLM-2 [nTPM]":"19.4","Cell RNA - HEK 293 [nTPM]":"10.2","Cell RNA - HEL [nTPM]":"32.7","Cell RNA - HeLa [nTPM]":"17.9","Cell RNA - Hep G2 [nTPM]":"9.0","Cell RNA - HHSteC [nTPM]":"16.5","Cell RNA - HL-60 [nTPM]":"7.5","Cell RNA - HMC-1 [nTPM]":"7.6","Cell RNA - HSkMC [nTPM]":"12.1","Cell RNA - hTCEpi [nTPM]":"23.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.0","Cell RNA - hTERT-HME1 [nTPM]":"21.7","Cell RNA - hTERT-RPE1 [nTPM]":"8.7","Cell RNA - HUVEC TERT2 [nTPM]":"19.3","Cell RNA - JURKAT [nTPM]":"7.9","Cell RNA - K-562 [nTPM]":"62.6","Cell RNA - Karpas-707 [nTPM]":"32.2","Cell RNA - LHCN-M2 [nTPM]":"14.6","Cell RNA - MCF7 [nTPM]":"12.7","Cell RNA - MOLT-4 [nTPM]":"3.3","Cell RNA - NB-4 [nTPM]":"4.2","Cell RNA - NTERA-2 [nTPM]":"9.2","Cell RNA - OE19 [nTPM]":"13.7","Cell RNA - PC-3 [nTPM]":"13.7","Cell RNA - REH [nTPM]":"5.5","Cell RNA - RH-30 [nTPM]":"18.4","Cell RNA - RPMI-8226 [nTPM]":"8.8","Cell RNA - RPTEC TERT1 [nTPM]":"19.7","Cell RNA - RT4 [nTPM]":"31.2","Cell RNA - SCLC-21H [nTPM]":"6.2","Cell RNA - SH-SY5Y [nTPM]":"4.9","Cell RNA - SiHa [nTPM]":"14.4","Cell RNA - SK-BR-3 [nTPM]":"14.2","Cell RNA - SK-MEL-30 [nTPM]":"7.5","Cell RNA - SuSa [nTPM]":"11.3","Cell RNA - T-47d [nTPM]":"21.4","Cell RNA - THP-1 [nTPM]":"2.7","Cell RNA - TIME [nTPM]":"27.1","Cell RNA - U-138 MG [nTPM]":"14.6","Cell RNA - U-2 OS [nTPM]":"17.8","Cell RNA - U-2197 [nTPM]":"14.1","Cell RNA - U-251 MG [nTPM]":"14.6","Cell RNA - U-266\/70 [nTPM]":"11.0","Cell RNA - U-266\/84 [nTPM]":"9.5","Cell RNA - U-698 [nTPM]":"6.3","Cell RNA - U-87 MG [nTPM]":"18.2","Cell RNA - U-937 [nTPM]":"12.0","Cell RNA - WM-115 [nTPM]":"12.1","Blood RNA - basophil [nTPM]":"3.4","Blood RNA - classical monocyte [nTPM]":"9.3","Blood RNA - eosinophil [nTPM]":"28.4","Blood RNA - gdT-cell [nTPM]":"4.6","Blood RNA - intermediate monocyte [nTPM]":"4.9","Blood RNA - MAIT T-cell [nTPM]":"10.3","Blood RNA - memory B-cell [nTPM]":"7.0","Blood RNA - memory CD4 T-cell [nTPM]":"6.2","Blood RNA - memory CD8 T-cell [nTPM]":"6.8","Blood RNA - myeloid DC [nTPM]":"5.2","Blood RNA - naive B-cell [nTPM]":"6.5","Blood RNA - naive CD4 T-cell [nTPM]":"8.2","Blood RNA - naive CD8 T-cell [nTPM]":"5.4","Blood RNA - neutrophil [nTPM]":"16.7","Blood RNA - NK-cell [nTPM]":"10.1","Blood RNA - non-classical monocyte [nTPM]":"4.0","Blood RNA - plasmacytoid DC [nTPM]":"3.2","Blood RNA - T-reg [nTPM]":"15.6","Blood RNA - total PBMC [nTPM]":"6.3","Brain RNA - amygdala [nTPM]":"19.8","Brain RNA - basal ganglia [nTPM]":"27.4","Brain RNA - cerebellum [nTPM]":"21.5","Brain RNA - cerebral cortex [nTPM]":"20.3","Brain RNA - hippocampal formation [nTPM]":"17.2","Brain RNA - hypothalamus [nTPM]":"23.0","Brain RNA - medulla oblongata [nTPM]":"29.5","Brain RNA - midbrain [nTPM]":"24.1","Brain RNA - pons [nTPM]":"28.5","Brain RNA - spinal cord [nTPM]":"23.6","Brain RNA - thalamus [nTPM]":"23.4","Brain RNA - white matter [nTPM]":"41.3","Single Cell Type RNA - Adipocytes [nTPM]":"17.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"40.0","Single Cell Type RNA - Astrocytes [nTPM]":"106.7","Single Cell Type RNA - B-cells [nTPM]":"19.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"54.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"28.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.9","Single Cell Type RNA - Bipolar cells [nTPM]":"20.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"26.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"30.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"29.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"10.9","Single Cell Type RNA - dendritic cells [nTPM]":"15.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"17.6","Single Cell Type RNA - Early spermatids [nTPM]":"17.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"20.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.5","Single Cell Type RNA - Endothelial cells [nTPM]":"19.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.9","Single Cell Type RNA - Erythroid cells [nTPM]":"32.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"153.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"21.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.7","Single Cell Type RNA - Fibroblasts [nTPM]":"19.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"30.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"32.4","Single Cell Type RNA - granulocytes [nTPM]":"20.8","Single Cell Type RNA - Granulosa cells [nTPM]":"12.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.9","Single Cell Type RNA - Hepatocytes [nTPM]":"16.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"29.0","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"117.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.1","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"46.5","Single Cell Type RNA - Langerhans cells [nTPM]":"17.6","Single Cell Type RNA - Late spermatids [nTPM]":"30.6","Single Cell Type RNA - Leydig cells [nTPM]":"16.1","Single Cell Type RNA - Macrophages [nTPM]":"34.5","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"229.5","Single Cell Type RNA - monocytes [nTPM]":"12.4","Single Cell Type RNA - Muller glia cells [nTPM]":"17.4","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"313.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"422.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.7","Single Cell Type RNA - Paneth cells [nTPM]":"6.4","Single Cell Type RNA - Peritubular cells [nTPM]":"10.5","Single Cell Type RNA - Plasma cells [nTPM]":"13.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"32.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"25.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"36.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"27.1","Single Cell Type RNA - Spermatocytes [nTPM]":"12.8","Single Cell Type RNA - Spermatogonia [nTPM]":"2.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"83.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.9","Single Cell Type RNA - T-cells [nTPM]":"20.0","Single Cell Type RNA - Theca cells [nTPM]":"11.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.4","Single Cell Type RNA - Urothelial cells [nTPM]":"25.4"},{"Gene":"SIRT1","Gene synonym":["SIR2L1"],"Ensembl":"ENSG00000096717","Gene description":"Sirtuin 1","Uniprot":["Q96EB6"],"Chromosome":"10","Position":"67884656-67918390","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Apoptosis","Biological rhythms","Differentiation","Host-virus interaction","Myogenesis","Transcription","Transcription regulation"],"Molecular function":["Developmental protein","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Early spermatids":"292.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB003855","HPA006295","HPA052351"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli fibrillar center","Mitochondria","Cytosol"],"Antibody RRID":{"CAB003855":"AB_365497","HPA006295":"AB_1079975","HPA052351":"AB_2681796"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.64e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.61e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.67e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Tissue RNA - adipose tissue [nTPM]":"16.4","Tissue RNA - adrenal gland [nTPM]":"30.2","Tissue RNA - amygdala [nTPM]":"8.9","Tissue RNA - appendix [nTPM]":"11.0","Tissue RNA - basal ganglia [nTPM]":"10.4","Tissue RNA - bone marrow [nTPM]":"19.8","Tissue RNA - breast [nTPM]":"17.5","Tissue RNA - cerebellum [nTPM]":"15.6","Tissue RNA - cerebral cortex [nTPM]":"11.9","Tissue RNA - cervix [nTPM]":"17.1","Tissue RNA - choroid plexus [nTPM]":"7.8","Tissue RNA - colon [nTPM]":"12.5","Tissue RNA - duodenum [nTPM]":"9.2","Tissue RNA - endometrium 1 [nTPM]":"18.5","Tissue RNA - epididymis [nTPM]":"11.9","Tissue RNA - esophagus [nTPM]":"10.9","Tissue RNA - fallopian tube [nTPM]":"11.9","Tissue RNA - gallbladder [nTPM]":"14.0","Tissue RNA - heart muscle [nTPM]":"10.6","Tissue RNA - hippocampal formation [nTPM]":"8.5","Tissue RNA - hypothalamus [nTPM]":"9.9","Tissue RNA - kidney [nTPM]":"13.4","Tissue RNA - liver [nTPM]":"17.3","Tissue RNA - lung [nTPM]":"12.6","Tissue RNA - lymph node [nTPM]":"17.7","Tissue RNA - medulla oblongata [nTPM]":"9.3","Tissue RNA - midbrain [nTPM]":"9.2","Tissue RNA - ovary [nTPM]":"25.1","Tissue RNA - pancreas [nTPM]":"12.1","Tissue RNA - parathyroid gland [nTPM]":"14.0","Tissue RNA - pituitary gland [nTPM]":"6.9","Tissue RNA - placenta [nTPM]":"12.7","Tissue RNA - pons [nTPM]":"10.0","Tissue RNA - prostate [nTPM]":"14.0","Tissue RNA - rectum [nTPM]":"12.0","Tissue RNA - retina [nTPM]":"13.5","Tissue RNA - salivary gland [nTPM]":"9.9","Tissue RNA - seminal vesicle [nTPM]":"11.2","Tissue RNA - skeletal muscle [nTPM]":"14.6","Tissue RNA - skin 1 [nTPM]":"9.6","Tissue RNA - small intestine [nTPM]":"9.7","Tissue RNA - smooth muscle [nTPM]":"13.7","Tissue RNA - spinal cord [nTPM]":"8.8","Tissue RNA - spleen [nTPM]":"14.3","Tissue RNA - stomach 1 [nTPM]":"10.3","Tissue RNA - testis [nTPM]":"26.8","Tissue RNA - thalamus [nTPM]":"9.4","Tissue RNA - thymus [nTPM]":"19.2","Tissue RNA - thyroid gland [nTPM]":"14.7","Tissue RNA - tongue [nTPM]":"18.5","Tissue RNA - tonsil [nTPM]":"15.1","Tissue RNA - urinary bladder [nTPM]":"15.5","Tissue RNA - vagina [nTPM]":"9.5","Tissue RNA - white matter [nTPM]":"12.9","Cell RNA - A-431 [nTPM]":"15.1","Cell RNA - A549 [nTPM]":"16.8","Cell RNA - AF22 [nTPM]":"26.2","Cell RNA - AN3-CA [nTPM]":"29.4","Cell RNA - ASC diff [nTPM]":"24.4","Cell RNA - ASC TERT1 [nTPM]":"18.7","Cell RNA - BEWO [nTPM]":"16.3","Cell RNA - BJ [nTPM]":"20.4","Cell RNA - BJ hTERT+ [nTPM]":"21.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"27.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"24.3","Cell RNA - CACO-2 [nTPM]":"18.7","Cell RNA - CAPAN-2 [nTPM]":"12.6","Cell RNA - Daudi [nTPM]":"31.4","Cell RNA - EFO-21 [nTPM]":"10.8","Cell RNA - fHDF\/TERT166 [nTPM]":"13.7","Cell RNA - GAMG [nTPM]":"17.1","Cell RNA - HaCaT [nTPM]":"11.7","Cell RNA - HAP1 [nTPM]":"32.8","Cell RNA - HBEC3-KT [nTPM]":"6.9","Cell RNA - HBF TERT88 [nTPM]":"29.3","Cell RNA - HDLM-2 [nTPM]":"16.9","Cell RNA - HEK 293 [nTPM]":"19.0","Cell RNA - HEL [nTPM]":"16.7","Cell RNA - HeLa [nTPM]":"12.1","Cell RNA - Hep G2 [nTPM]":"14.7","Cell RNA - HHSteC [nTPM]":"22.3","Cell RNA - HL-60 [nTPM]":"18.1","Cell RNA - HMC-1 [nTPM]":"12.3","Cell RNA - HSkMC [nTPM]":"17.3","Cell RNA - hTCEpi [nTPM]":"16.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"16.6","Cell RNA - hTERT-HME1 [nTPM]":"28.3","Cell RNA - hTERT-RPE1 [nTPM]":"29.4","Cell RNA - HUVEC TERT2 [nTPM]":"11.2","Cell RNA - JURKAT [nTPM]":"17.6","Cell RNA - K-562 [nTPM]":"21.6","Cell RNA - Karpas-707 [nTPM]":"16.7","Cell RNA - LHCN-M2 [nTPM]":"20.3","Cell RNA - MCF7 [nTPM]":"12.1","Cell RNA - MOLT-4 [nTPM]":"17.0","Cell RNA - NB-4 [nTPM]":"25.0","Cell RNA - NTERA-2 [nTPM]":"32.5","Cell RNA - OE19 [nTPM]":"9.6","Cell RNA - PC-3 [nTPM]":"26.6","Cell RNA - REH [nTPM]":"30.3","Cell RNA - RH-30 [nTPM]":"20.6","Cell RNA - RPMI-8226 [nTPM]":"12.4","Cell RNA - RPTEC TERT1 [nTPM]":"13.1","Cell RNA - RT4 [nTPM]":"9.1","Cell RNA - SCLC-21H [nTPM]":"16.8","Cell RNA - SH-SY5Y [nTPM]":"23.0","Cell RNA - SiHa [nTPM]":"37.4","Cell RNA - SK-BR-3 [nTPM]":"24.4","Cell RNA - SK-MEL-30 [nTPM]":"26.8","Cell RNA - SuSa [nTPM]":"22.5","Cell RNA - T-47d [nTPM]":"17.7","Cell RNA - THP-1 [nTPM]":"16.6","Cell RNA - TIME [nTPM]":"9.4","Cell RNA - U-138 MG [nTPM]":"21.2","Cell RNA - U-2 OS [nTPM]":"19.8","Cell RNA - U-2197 [nTPM]":"19.0","Cell RNA - U-251 MG [nTPM]":"20.1","Cell RNA - U-266\/70 [nTPM]":"13.9","Cell RNA - U-266\/84 [nTPM]":"17.7","Cell RNA - U-698 [nTPM]":"61.8","Cell RNA - U-87 MG [nTPM]":"10.9","Cell RNA - U-937 [nTPM]":"27.2","Cell RNA - WM-115 [nTPM]":"8.9","Blood RNA - basophil [nTPM]":"1.3","Blood RNA - classical monocyte [nTPM]":"0.8","Blood RNA - eosinophil [nTPM]":"1.1","Blood RNA - gdT-cell [nTPM]":"1.1","Blood RNA - intermediate monocyte [nTPM]":"1.0","Blood RNA - MAIT T-cell [nTPM]":"1.6","Blood RNA - memory B-cell [nTPM]":"1.8","Blood RNA - memory CD4 T-cell [nTPM]":"1.2","Blood RNA - memory CD8 T-cell [nTPM]":"1.5","Blood RNA - myeloid DC [nTPM]":"1.3","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"2.2","Blood RNA - naive CD8 T-cell [nTPM]":"1.3","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"1.2","Blood RNA - non-classical monocyte [nTPM]":"1.3","Blood RNA - plasmacytoid DC [nTPM]":"1.2","Blood RNA - T-reg [nTPM]":"1.0","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"8.9","Brain RNA - basal ganglia [nTPM]":"10.4","Brain RNA - cerebellum [nTPM]":"15.6","Brain RNA - cerebral cortex [nTPM]":"11.9","Brain RNA - hippocampal formation [nTPM]":"8.5","Brain RNA - hypothalamus [nTPM]":"9.9","Brain RNA - medulla oblongata [nTPM]":"9.3","Brain RNA - midbrain [nTPM]":"9.2","Brain RNA - pons [nTPM]":"10.0","Brain RNA - spinal cord [nTPM]":"8.8","Brain RNA - thalamus [nTPM]":"9.4","Brain RNA - white matter [nTPM]":"12.9","Single Cell Type RNA - Adipocytes [nTPM]":"35.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.4","Single Cell Type RNA - Astrocytes [nTPM]":"17.0","Single Cell Type RNA - B-cells [nTPM]":"27.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"39.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"22.8","Single Cell Type RNA - Bipolar cells [nTPM]":"12.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"48.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"33.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"34.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"8.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.1","Single Cell Type RNA - dendritic cells [nTPM]":"42.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"31.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.3","Single Cell Type RNA - Early spermatids [nTPM]":"292.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"38.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"26.2","Single Cell Type RNA - Endothelial cells [nTPM]":"20.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"42.9","Single Cell Type RNA - Erythroid cells [nTPM]":"10.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"16.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.4","Single Cell Type RNA - Fibroblasts [nTPM]":"28.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"57.1","Single Cell Type RNA - granulocytes [nTPM]":"12.0","Single Cell Type RNA - Granulosa cells [nTPM]":"14.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.4","Single Cell Type RNA - Hepatocytes [nTPM]":"15.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.1","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"21.0","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"23.4","Single Cell Type RNA - Langerhans cells [nTPM]":"28.7","Single Cell Type RNA - Late spermatids [nTPM]":"45.6","Single Cell Type RNA - Leydig cells [nTPM]":"17.7","Single Cell Type RNA - Macrophages [nTPM]":"34.1","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"30.9","Single Cell Type RNA - monocytes [nTPM]":"14.8","Single Cell Type RNA - Muller glia cells [nTPM]":"7.1","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"30.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.2","Single Cell Type RNA - Paneth cells [nTPM]":"20.6","Single Cell Type RNA - Peritubular cells [nTPM]":"19.5","Single Cell Type RNA - Plasma cells [nTPM]":"15.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"26.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"43.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"28.8","Single Cell Type RNA - Spermatocytes [nTPM]":"24.2","Single Cell Type RNA - Spermatogonia [nTPM]":"16.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"21.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"47.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.4","Single Cell Type RNA - T-cells [nTPM]":"29.1","Single Cell Type RNA - Theca cells [nTPM]":"8.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.7","Single Cell Type RNA - Urothelial cells [nTPM]":"17.2"},{"Gene":"SPECC1","Gene synonym":["CYTSB","FLJ36955","HCMOGT-1","NSP"],"Ensembl":"ENSG00000128487","Gene description":"Sperm antigen with calponin homology and coiled-coil domains 1","Uniprot":["Q5M775"],"Chromosome":"17","Position":"20008865-20319026","Protein class":["Disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"47.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"217.1","Inhibitory neurons":"220.8","Microglial cells":"187.4","Oligodendrocytes":"317.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"42.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SiHa":"75.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA021421","HPA021430","HPA061073"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"9800","Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 38: EFO-21 - Unknown function","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":["Nucleoli fibrillar center","Cytosol"],"Antibody RRID":{"HPA021421":"AB_1857431","HPA021430":"AB_1857432","HPA061073":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.32e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.06e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.23e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.86e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Tissue RNA - adipose tissue [nTPM]":"12.5","Tissue RNA - adrenal gland [nTPM]":"9.6","Tissue RNA - amygdala [nTPM]":"30.8","Tissue RNA - appendix [nTPM]":"7.3","Tissue RNA - basal ganglia [nTPM]":"35.1","Tissue RNA - bone marrow [nTPM]":"23.6","Tissue RNA - breast [nTPM]":"9.2","Tissue RNA - cerebellum [nTPM]":"24.1","Tissue RNA - cerebral cortex [nTPM]":"43.7","Tissue RNA - cervix [nTPM]":"6.1","Tissue RNA - choroid plexus [nTPM]":"22.3","Tissue RNA - colon [nTPM]":"15.1","Tissue RNA - duodenum [nTPM]":"9.8","Tissue RNA - endometrium 1 [nTPM]":"12.8","Tissue RNA - epididymis [nTPM]":"4.7","Tissue RNA - esophagus [nTPM]":"9.2","Tissue RNA - fallopian tube [nTPM]":"8.3","Tissue RNA - gallbladder [nTPM]":"14.8","Tissue RNA - heart muscle [nTPM]":"5.0","Tissue RNA - hippocampal formation [nTPM]":"41.4","Tissue RNA - hypothalamus [nTPM]":"21.4","Tissue RNA - kidney [nTPM]":"4.7","Tissue RNA - liver [nTPM]":"1.2","Tissue RNA - lung [nTPM]":"5.7","Tissue RNA - lymph node [nTPM]":"5.3","Tissue RNA - medulla oblongata [nTPM]":"32.8","Tissue RNA - midbrain [nTPM]":"25.8","Tissue RNA - ovary [nTPM]":"16.6","Tissue RNA - pancreas [nTPM]":"4.8","Tissue RNA - parathyroid gland [nTPM]":"3.3","Tissue RNA - pituitary gland [nTPM]":"6.4","Tissue RNA - placenta [nTPM]":"3.6","Tissue RNA - pons [nTPM]":"24.5","Tissue RNA - prostate [nTPM]":"6.1","Tissue RNA - rectum [nTPM]":"10.0","Tissue RNA - retina [nTPM]":"6.1","Tissue RNA - salivary gland [nTPM]":"6.2","Tissue RNA - seminal vesicle [nTPM]":"5.0","Tissue RNA - skeletal muscle [nTPM]":"5.1","Tissue RNA - skin 1 [nTPM]":"3.6","Tissue RNA - small intestine [nTPM]":"10.5","Tissue RNA - smooth muscle [nTPM]":"9.5","Tissue RNA - spinal cord [nTPM]":"21.0","Tissue RNA - spleen [nTPM]":"13.5","Tissue RNA - stomach 1 [nTPM]":"10.3","Tissue RNA - testis [nTPM]":"22.8","Tissue RNA - thalamus [nTPM]":"41.1","Tissue RNA - thymus [nTPM]":"3.0","Tissue RNA - thyroid gland [nTPM]":"5.2","Tissue RNA - tongue [nTPM]":"2.8","Tissue RNA - tonsil [nTPM]":"5.2","Tissue RNA - urinary bladder [nTPM]":"4.6","Tissue RNA - vagina [nTPM]":"4.3","Tissue RNA - white matter [nTPM]":"47.3","Cell RNA - A-431 [nTPM]":"26.2","Cell RNA - A549 [nTPM]":"37.3","Cell RNA - AF22 [nTPM]":"15.7","Cell RNA - AN3-CA [nTPM]":"7.2","Cell RNA - ASC diff [nTPM]":"14.7","Cell RNA - ASC TERT1 [nTPM]":"6.9","Cell RNA - BEWO [nTPM]":"29.1","Cell RNA - BJ [nTPM]":"10.0","Cell RNA - BJ hTERT+ [nTPM]":"12.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"12.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.4","Cell RNA - CACO-2 [nTPM]":"67.6","Cell RNA - CAPAN-2 [nTPM]":"17.1","Cell RNA - Daudi [nTPM]":"1.5","Cell RNA - EFO-21 [nTPM]":"45.3","Cell RNA - fHDF\/TERT166 [nTPM]":"11.4","Cell RNA - GAMG [nTPM]":"24.3","Cell RNA - HaCaT [nTPM]":"21.1","Cell RNA - HAP1 [nTPM]":"10.7","Cell RNA - HBEC3-KT [nTPM]":"33.4","Cell RNA - HBF TERT88 [nTPM]":"3.7","Cell RNA - HDLM-2 [nTPM]":"12.8","Cell RNA - HEK 293 [nTPM]":"18.5","Cell RNA - HEL [nTPM]":"14.5","Cell RNA - HeLa [nTPM]":"34.4","Cell RNA - Hep G2 [nTPM]":"10.5","Cell RNA - HHSteC [nTPM]":"4.9","Cell RNA - HL-60 [nTPM]":"1.3","Cell RNA - HMC-1 [nTPM]":"5.6","Cell RNA - HSkMC [nTPM]":"10.6","Cell RNA - hTCEpi [nTPM]":"36.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.2","Cell RNA - hTERT-HME1 [nTPM]":"24.9","Cell RNA - hTERT-RPE1 [nTPM]":"46.8","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"4.4","Cell RNA - K-562 [nTPM]":"1.0","Cell RNA - Karpas-707 [nTPM]":"15.1","Cell RNA - LHCN-M2 [nTPM]":"10.4","Cell RNA - MCF7 [nTPM]":"24.0","Cell RNA - MOLT-4 [nTPM]":"0.3","Cell RNA - NB-4 [nTPM]":"5.3","Cell RNA - NTERA-2 [nTPM]":"14.5","Cell RNA - OE19 [nTPM]":"17.0","Cell RNA - PC-3 [nTPM]":"6.3","Cell RNA - REH [nTPM]":"11.8","Cell RNA - RH-30 [nTPM]":"49.5","Cell RNA - RPMI-8226 [nTPM]":"23.6","Cell RNA - RPTEC TERT1 [nTPM]":"32.2","Cell RNA - RT4 [nTPM]":"11.4","Cell RNA - SCLC-21H [nTPM]":"7.1","Cell RNA - SH-SY5Y [nTPM]":"6.9","Cell RNA - SiHa [nTPM]":"75.7","Cell RNA - SK-BR-3 [nTPM]":"35.6","Cell RNA - SK-MEL-30 [nTPM]":"13.9","Cell RNA - SuSa [nTPM]":"62.2","Cell RNA - T-47d [nTPM]":"26.3","Cell RNA - THP-1 [nTPM]":"9.1","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.5","Cell RNA - U-2 OS [nTPM]":"21.1","Cell RNA - U-2197 [nTPM]":"0.9","Cell RNA - U-251 MG [nTPM]":"30.8","Cell RNA - U-266\/70 [nTPM]":"5.4","Cell RNA - U-266\/84 [nTPM]":"11.7","Cell RNA - U-698 [nTPM]":"0.9","Cell RNA - U-87 MG [nTPM]":"19.1","Cell RNA - U-937 [nTPM]":"12.6","Cell RNA - WM-115 [nTPM]":"6.5","Blood RNA - basophil [nTPM]":"42.1","Blood RNA - classical monocyte [nTPM]":"15.8","Blood RNA - eosinophil [nTPM]":"33.0","Blood RNA - gdT-cell [nTPM]":"2.2","Blood RNA - intermediate monocyte [nTPM]":"8.4","Blood RNA - MAIT T-cell [nTPM]":"3.2","Blood RNA - memory B-cell [nTPM]":"1.8","Blood RNA - memory CD4 T-cell [nTPM]":"1.5","Blood RNA - memory CD8 T-cell [nTPM]":"3.4","Blood RNA - myeloid DC [nTPM]":"26.6","Blood RNA - naive B-cell [nTPM]":"1.4","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"1.4","Blood RNA - neutrophil [nTPM]":"11.1","Blood RNA - NK-cell [nTPM]":"13.0","Blood RNA - non-classical monocyte [nTPM]":"7.9","Blood RNA - plasmacytoid DC [nTPM]":"4.6","Blood RNA - T-reg [nTPM]":"0.6","Blood RNA - total PBMC [nTPM]":"5.5","Brain RNA - amygdala [nTPM]":"30.8","Brain RNA - basal ganglia [nTPM]":"35.1","Brain RNA - cerebellum [nTPM]":"24.1","Brain RNA - cerebral cortex [nTPM]":"43.7","Brain RNA - hippocampal formation [nTPM]":"41.4","Brain RNA - hypothalamus [nTPM]":"21.4","Brain RNA - medulla oblongata [nTPM]":"32.8","Brain RNA - midbrain [nTPM]":"25.8","Brain RNA - pons [nTPM]":"24.5","Brain RNA - spinal cord [nTPM]":"21.0","Brain RNA - thalamus [nTPM]":"41.1","Brain RNA - white matter [nTPM]":"47.3","Single Cell Type RNA - Adipocytes [nTPM]":"28.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.7","Single Cell Type RNA - Astrocytes [nTPM]":"170.4","Single Cell Type RNA - B-cells [nTPM]":"5.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"22.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Bipolar cells [nTPM]":"7.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"21.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"68.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.5","Single Cell Type RNA - dendritic cells [nTPM]":"10.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"56.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"30.9","Single Cell Type RNA - Early spermatids [nTPM]":"100.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"40.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"44.1","Single Cell Type RNA - Endothelial cells [nTPM]":"13.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.7","Single Cell Type RNA - Erythroid cells [nTPM]":"82.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"217.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"36.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.5","Single Cell Type RNA - Fibroblasts [nTPM]":"18.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"34.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"64.1","Single Cell Type RNA - granulocytes [nTPM]":"116.4","Single Cell Type RNA - Granulosa cells [nTPM]":"29.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"22.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"220.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"54.8","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"12.4","Single Cell Type RNA - Langerhans cells [nTPM]":"15.9","Single Cell Type RNA - Late spermatids [nTPM]":"54.5","Single Cell Type RNA - Leydig cells [nTPM]":"5.0","Single Cell Type RNA - Macrophages [nTPM]":"29.0","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"187.4","Single Cell Type RNA - monocytes [nTPM]":"84.7","Single Cell Type RNA - Muller glia cells [nTPM]":"13.6","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"125.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"317.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"67.7","Single Cell Type RNA - Paneth cells [nTPM]":"24.7","Single Cell Type RNA - Peritubular cells [nTPM]":"44.8","Single Cell Type RNA - Plasma cells [nTPM]":"7.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"25.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"18.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"31.4","Single Cell Type RNA - Sertoli cells [nTPM]":"59.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"81.3","Single Cell Type RNA - Spermatocytes [nTPM]":"73.8","Single Cell Type RNA - Spermatogonia [nTPM]":"68.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.2","Single Cell Type RNA - T-cells [nTPM]":"10.0","Single Cell Type RNA - Theca cells [nTPM]":"87.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"27.4","Single Cell Type RNA - Urothelial cells [nTPM]":"21.5"},{"Gene":"SPNS1","Gene synonym":["HSpin1","LAT","nrs","PP2030","SLC62A1","SPIN1","SPINL"],"Ensembl":"ENSG00000169682","Gene description":"Sphingolipid transporter 1 (putative)","Uniprot":["Q9H2V7"],"Chromosome":"16","Position":"28974221-28984548","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041995","HPA042988"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center","Golgi apparatus","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 51: Myeloid cells - Hemostasis","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoli fibrillar center","Golgi apparatus","Cytosol"],"Antibody RRID":{"HPA041995":"AB_10959609","HPA042988":"AB_10964587"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.86e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.12e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.15e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Tissue RNA - adipose tissue [nTPM]":"26.8","Tissue RNA - adrenal gland [nTPM]":"30.8","Tissue RNA - amygdala [nTPM]":"17.0","Tissue RNA - appendix [nTPM]":"19.3","Tissue RNA - basal ganglia [nTPM]":"17.4","Tissue RNA - bone marrow [nTPM]":"37.0","Tissue RNA - breast [nTPM]":"24.8","Tissue RNA - cerebellum [nTPM]":"17.1","Tissue RNA - cerebral cortex [nTPM]":"26.3","Tissue RNA - cervix [nTPM]":"27.7","Tissue RNA - choroid plexus [nTPM]":"18.6","Tissue RNA - colon [nTPM]":"32.5","Tissue RNA - duodenum [nTPM]":"22.4","Tissue RNA - endometrium 1 [nTPM]":"30.9","Tissue RNA - epididymis [nTPM]":"6.6","Tissue RNA - esophagus [nTPM]":"25.9","Tissue RNA - fallopian tube [nTPM]":"23.0","Tissue RNA - gallbladder [nTPM]":"18.0","Tissue RNA - heart muscle [nTPM]":"27.5","Tissue RNA - hippocampal formation [nTPM]":"16.9","Tissue RNA - hypothalamus [nTPM]":"15.7","Tissue RNA - kidney [nTPM]":"32.1","Tissue RNA - liver [nTPM]":"33.9","Tissue RNA - lung [nTPM]":"31.5","Tissue RNA - lymph node [nTPM]":"20.1","Tissue RNA - medulla oblongata [nTPM]":"19.1","Tissue RNA - midbrain [nTPM]":"16.6","Tissue RNA - ovary [nTPM]":"22.0","Tissue RNA - pancreas [nTPM]":"24.4","Tissue RNA - parathyroid gland [nTPM]":"20.8","Tissue RNA - pituitary gland [nTPM]":"21.1","Tissue RNA - placenta [nTPM]":"19.8","Tissue RNA - pons [nTPM]":"17.2","Tissue RNA - prostate [nTPM]":"26.5","Tissue RNA - rectum [nTPM]":"10.0","Tissue RNA - retina [nTPM]":"6.5","Tissue RNA - salivary gland [nTPM]":"24.4","Tissue RNA - seminal vesicle [nTPM]":"14.9","Tissue RNA - skeletal muscle [nTPM]":"25.0","Tissue RNA - skin 1 [nTPM]":"35.7","Tissue RNA - small intestine [nTPM]":"27.8","Tissue RNA - smooth muscle [nTPM]":"15.1","Tissue RNA - spinal cord [nTPM]":"15.8","Tissue RNA - spleen [nTPM]":"33.9","Tissue RNA - stomach 1 [nTPM]":"28.2","Tissue RNA - testis [nTPM]":"20.3","Tissue RNA - thalamus [nTPM]":"19.8","Tissue RNA - thymus [nTPM]":"20.8","Tissue RNA - thyroid gland [nTPM]":"27.8","Tissue RNA - tongue [nTPM]":"14.9","Tissue RNA - tonsil [nTPM]":"10.5","Tissue RNA - urinary bladder [nTPM]":"30.5","Tissue RNA - vagina [nTPM]":"25.2","Tissue RNA - white matter [nTPM]":"18.3","Cell RNA - A-431 [nTPM]":"25.9","Cell RNA - A549 [nTPM]":"59.6","Cell RNA - AF22 [nTPM]":"22.2","Cell RNA - AN3-CA [nTPM]":"51.9","Cell RNA - ASC diff [nTPM]":"41.5","Cell RNA - ASC TERT1 [nTPM]":"22.8","Cell RNA - BEWO [nTPM]":"62.9","Cell RNA - BJ [nTPM]":"28.2","Cell RNA - BJ hTERT+ [nTPM]":"28.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"46.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"40.9","Cell RNA - CACO-2 [nTPM]":"55.0","Cell RNA - CAPAN-2 [nTPM]":"60.4","Cell RNA - Daudi [nTPM]":"16.4","Cell RNA - EFO-21 [nTPM]":"67.8","Cell RNA - fHDF\/TERT166 [nTPM]":"25.5","Cell RNA - GAMG [nTPM]":"38.2","Cell RNA - HaCaT [nTPM]":"53.3","Cell RNA - HAP1 [nTPM]":"36.4","Cell RNA - HBEC3-KT [nTPM]":"31.2","Cell RNA - HBF TERT88 [nTPM]":"16.4","Cell RNA - HDLM-2 [nTPM]":"19.0","Cell RNA - HEK 293 [nTPM]":"61.6","Cell RNA - HEL [nTPM]":"23.8","Cell RNA - HeLa [nTPM]":"57.1","Cell RNA - Hep G2 [nTPM]":"69.3","Cell RNA - HHSteC [nTPM]":"70.4","Cell RNA - HL-60 [nTPM]":"26.7","Cell RNA - HMC-1 [nTPM]":"49.2","Cell RNA - HSkMC [nTPM]":"38.4","Cell RNA - hTCEpi [nTPM]":"40.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"49.7","Cell RNA - hTERT-HME1 [nTPM]":"21.0","Cell RNA - hTERT-RPE1 [nTPM]":"26.8","Cell RNA - HUVEC TERT2 [nTPM]":"42.9","Cell RNA - JURKAT [nTPM]":"30.0","Cell RNA - K-562 [nTPM]":"54.4","Cell RNA - Karpas-707 [nTPM]":"28.7","Cell RNA - LHCN-M2 [nTPM]":"23.4","Cell RNA - MCF7 [nTPM]":"68.8","Cell RNA - MOLT-4 [nTPM]":"29.3","Cell RNA - NB-4 [nTPM]":"75.8","Cell RNA - NTERA-2 [nTPM]":"52.6","Cell RNA - OE19 [nTPM]":"20.8","Cell RNA - PC-3 [nTPM]":"39.1","Cell RNA - REH [nTPM]":"36.7","Cell RNA - RH-30 [nTPM]":"26.7","Cell RNA - RPMI-8226 [nTPM]":"73.6","Cell RNA - RPTEC TERT1 [nTPM]":"24.9","Cell RNA - RT4 [nTPM]":"24.8","Cell RNA - SCLC-21H [nTPM]":"39.5","Cell RNA - SH-SY5Y [nTPM]":"51.3","Cell RNA - SiHa [nTPM]":"20.1","Cell RNA - SK-BR-3 [nTPM]":"59.3","Cell RNA - SK-MEL-30 [nTPM]":"44.9","Cell RNA - SuSa [nTPM]":"18.5","Cell RNA - T-47d [nTPM]":"59.2","Cell RNA - THP-1 [nTPM]":"31.9","Cell RNA - TIME [nTPM]":"36.6","Cell RNA - U-138 MG [nTPM]":"37.3","Cell RNA - U-2 OS [nTPM]":"28.2","Cell RNA - U-2197 [nTPM]":"52.7","Cell RNA - U-251 MG [nTPM]":"22.0","Cell RNA - U-266\/70 [nTPM]":"43.2","Cell RNA - U-266\/84 [nTPM]":"36.7","Cell RNA - U-698 [nTPM]":"15.6","Cell RNA - U-87 MG [nTPM]":"47.7","Cell RNA - U-937 [nTPM]":"40.4","Cell RNA - WM-115 [nTPM]":"30.8","Blood RNA - basophil [nTPM]":"13.4","Blood RNA - classical monocyte [nTPM]":"32.8","Blood RNA - eosinophil [nTPM]":"13.5","Blood RNA - gdT-cell [nTPM]":"9.9","Blood RNA - intermediate monocyte [nTPM]":"42.1","Blood RNA - MAIT T-cell [nTPM]":"8.3","Blood RNA - memory B-cell [nTPM]":"5.7","Blood RNA - memory CD4 T-cell [nTPM]":"9.8","Blood RNA - memory CD8 T-cell [nTPM]":"13.0","Blood RNA - myeloid DC [nTPM]":"27.6","Blood RNA - naive B-cell [nTPM]":"4.3","Blood RNA - naive CD4 T-cell [nTPM]":"10.0","Blood RNA - naive CD8 T-cell [nTPM]":"6.8","Blood RNA - neutrophil [nTPM]":"5.6","Blood RNA - NK-cell [nTPM]":"7.7","Blood RNA - non-classical monocyte [nTPM]":"28.8","Blood RNA - plasmacytoid DC [nTPM]":"11.5","Blood RNA - T-reg [nTPM]":"12.1","Blood RNA - total PBMC [nTPM]":"18.1","Brain RNA - amygdala [nTPM]":"17.0","Brain RNA - basal ganglia [nTPM]":"17.4","Brain RNA - cerebellum [nTPM]":"17.1","Brain RNA - cerebral cortex [nTPM]":"26.3","Brain RNA - hippocampal formation [nTPM]":"16.9","Brain RNA - hypothalamus [nTPM]":"15.7","Brain RNA - medulla oblongata [nTPM]":"19.1","Brain RNA - midbrain [nTPM]":"16.6","Brain RNA - pons [nTPM]":"17.2","Brain RNA - spinal cord [nTPM]":"15.8","Brain RNA - thalamus [nTPM]":"19.8","Brain RNA - white matter [nTPM]":"18.3","Single Cell Type RNA - Adipocytes [nTPM]":"24.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.2","Single Cell Type RNA - Astrocytes [nTPM]":"8.8","Single Cell Type RNA - B-cells [nTPM]":"14.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"21.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"21.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"29.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.8","Single Cell Type RNA - Bipolar cells [nTPM]":"31.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"17.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"20.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"63.3","Single Cell Type RNA - dendritic cells [nTPM]":"26.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"58.1","Single Cell Type RNA - Early spermatids [nTPM]":"2.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.2","Single Cell Type RNA - Endothelial cells [nTPM]":"24.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.2","Single Cell Type RNA - Erythroid cells [nTPM]":"21.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"45.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"72.3","Single Cell Type RNA - Fibroblasts [nTPM]":"24.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.9","Single Cell Type RNA - granulocytes [nTPM]":"22.7","Single Cell Type RNA - Granulosa cells [nTPM]":"40.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"19.2","Single Cell Type RNA - Hepatocytes [nTPM]":"14.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"98.7","Single Cell Type RNA - Horizontal cells [nTPM]":"26.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.8","Single Cell Type RNA - Ionocytes [nTPM]":"46.8","Single Cell Type RNA - Kupffer cells [nTPM]":"45.6","Single Cell Type RNA - Langerhans cells [nTPM]":"28.4","Single Cell Type RNA - Late spermatids [nTPM]":"3.7","Single Cell Type RNA - Leydig cells [nTPM]":"22.7","Single Cell Type RNA - Macrophages [nTPM]":"61.8","Single Cell Type RNA - Melanocytes [nTPM]":"33.8","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"32.7","Single Cell Type RNA - Muller glia cells [nTPM]":"28.5","Single Cell Type RNA - NK-cells [nTPM]":"24.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"37.3","Single Cell Type RNA - Paneth cells [nTPM]":"16.0","Single Cell Type RNA - Peritubular cells [nTPM]":"16.6","Single Cell Type RNA - Plasma cells [nTPM]":"18.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"41.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"18.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"26.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"38.6","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"23.8","Single Cell Type RNA - Spermatocytes [nTPM]":"24.8","Single Cell Type RNA - Spermatogonia [nTPM]":"33.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"22.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"87.3","Single Cell Type RNA - T-cells [nTPM]":"20.7","Single Cell Type RNA - Theca cells [nTPM]":"37.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.0","Single Cell Type RNA - Urothelial cells [nTPM]":"19.4"},{"Gene":"TMEM62","Gene synonym":["FLJ23375"],"Ensembl":"ENSG00000137842","Gene description":"Transmembrane protein 62","Uniprot":["Q0P6H9"],"Chromosome":"15","Position":"43123279-43185144","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"OE19":"61.0","U-266\/84":"67.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044461","HPA062359"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center","Nuclear bodies","Cytoplasmic bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 16: U-266 - Nucleosome","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Nucleoplasm","Nucleoli fibrillar center","Nuclear bodies","Cytoplasmic bodies"],"Subcellular additional location":null,"Antibody RRID":{"HPA044461":"AB_2678950","HPA062359":"AB_2684747"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.43e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.72e-7"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.61e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.48e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.1","Tissue RNA - adrenal gland [nTPM]":"4.6","Tissue RNA - amygdala [nTPM]":"4.8","Tissue RNA - appendix [nTPM]":"6.0","Tissue RNA - basal ganglia [nTPM]":"5.0","Tissue RNA - bone marrow [nTPM]":"9.0","Tissue RNA - breast [nTPM]":"22.9","Tissue RNA - cerebellum [nTPM]":"8.2","Tissue RNA - cerebral cortex [nTPM]":"6.7","Tissue RNA - cervix [nTPM]":"8.1","Tissue RNA - choroid plexus [nTPM]":"3.6","Tissue RNA - colon [nTPM]":"13.1","Tissue RNA - duodenum [nTPM]":"13.1","Tissue RNA - endometrium 1 [nTPM]":"5.4","Tissue RNA - epididymis [nTPM]":"12.3","Tissue RNA - esophagus [nTPM]":"6.2","Tissue RNA - fallopian tube [nTPM]":"7.5","Tissue RNA - gallbladder [nTPM]":"7.9","Tissue RNA - heart muscle [nTPM]":"5.1","Tissue RNA - hippocampal formation [nTPM]":"5.3","Tissue RNA - hypothalamus [nTPM]":"4.8","Tissue RNA - kidney [nTPM]":"7.6","Tissue RNA - liver [nTPM]":"10.3","Tissue RNA - lung [nTPM]":"8.8","Tissue RNA - lymph node [nTPM]":"7.2","Tissue RNA - medulla oblongata [nTPM]":"4.5","Tissue RNA - midbrain [nTPM]":"4.5","Tissue RNA - ovary [nTPM]":"3.2","Tissue RNA - pancreas [nTPM]":"8.1","Tissue RNA - parathyroid gland [nTPM]":"13.7","Tissue RNA - pituitary gland [nTPM]":"4.6","Tissue RNA - placenta [nTPM]":"10.3","Tissue RNA - pons [nTPM]":"5.0","Tissue RNA - prostate [nTPM]":"6.1","Tissue RNA - rectum [nTPM]":"14.4","Tissue RNA - retina [nTPM]":"8.9","Tissue RNA - salivary gland [nTPM]":"13.6","Tissue RNA - seminal vesicle [nTPM]":"7.1","Tissue RNA - skeletal muscle [nTPM]":"9.4","Tissue RNA - skin 1 [nTPM]":"5.2","Tissue RNA - small intestine [nTPM]":"11.7","Tissue RNA - smooth muscle [nTPM]":"6.5","Tissue RNA - spinal cord [nTPM]":"5.0","Tissue RNA - spleen [nTPM]":"6.1","Tissue RNA - stomach 1 [nTPM]":"10.2","Tissue RNA - testis [nTPM]":"2.0","Tissue RNA - thalamus [nTPM]":"5.4","Tissue RNA - thymus [nTPM]":"4.0","Tissue RNA - thyroid gland [nTPM]":"8.5","Tissue RNA - tongue [nTPM]":"6.6","Tissue RNA - tonsil [nTPM]":"8.0","Tissue RNA - urinary bladder [nTPM]":"7.6","Tissue RNA - vagina [nTPM]":"5.4","Tissue RNA - white matter [nTPM]":"5.6","Cell RNA - A-431 [nTPM]":"14.9","Cell RNA - A549 [nTPM]":"7.9","Cell RNA - AF22 [nTPM]":"3.5","Cell RNA - AN3-CA [nTPM]":"6.8","Cell RNA - ASC diff [nTPM]":"4.3","Cell RNA - ASC TERT1 [nTPM]":"5.5","Cell RNA - BEWO [nTPM]":"36.4","Cell RNA - BJ [nTPM]":"13.9","Cell RNA - BJ hTERT+ [nTPM]":"17.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"24.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"33.3","Cell RNA - CACO-2 [nTPM]":"12.5","Cell RNA - CAPAN-2 [nTPM]":"28.5","Cell RNA - Daudi [nTPM]":"15.0","Cell RNA - EFO-21 [nTPM]":"7.9","Cell RNA - fHDF\/TERT166 [nTPM]":"13.2","Cell RNA - GAMG [nTPM]":"21.7","Cell RNA - HaCaT [nTPM]":"27.6","Cell RNA - HAP1 [nTPM]":"14.8","Cell RNA - HBEC3-KT [nTPM]":"10.9","Cell RNA - HBF TERT88 [nTPM]":"8.7","Cell RNA - HDLM-2 [nTPM]":"17.7","Cell RNA - HEK 293 [nTPM]":"6.8","Cell RNA - HEL [nTPM]":"12.2","Cell RNA - HeLa [nTPM]":"15.4","Cell RNA - Hep G2 [nTPM]":"9.5","Cell RNA - HHSteC [nTPM]":"9.4","Cell RNA - HL-60 [nTPM]":"12.7","Cell RNA - HMC-1 [nTPM]":"10.5","Cell RNA - HSkMC [nTPM]":"3.9","Cell RNA - hTCEpi [nTPM]":"13.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.6","Cell RNA - hTERT-HME1 [nTPM]":"7.4","Cell RNA - hTERT-RPE1 [nTPM]":"6.8","Cell RNA - HUVEC TERT2 [nTPM]":"13.6","Cell RNA - JURKAT [nTPM]":"3.7","Cell RNA - K-562 [nTPM]":"10.9","Cell RNA - Karpas-707 [nTPM]":"12.7","Cell RNA - LHCN-M2 [nTPM]":"2.8","Cell RNA - MCF7 [nTPM]":"3.5","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"3.0","Cell RNA - NTERA-2 [nTPM]":"1.2","Cell RNA - OE19 [nTPM]":"61.0","Cell RNA - PC-3 [nTPM]":"3.2","Cell RNA - REH [nTPM]":"7.5","Cell RNA - RH-30 [nTPM]":"3.7","Cell RNA - RPMI-8226 [nTPM]":"7.9","Cell RNA - RPTEC TERT1 [nTPM]":"12.9","Cell RNA - RT4 [nTPM]":"18.6","Cell RNA - SCLC-21H [nTPM]":"22.2","Cell RNA - SH-SY5Y [nTPM]":"9.6","Cell RNA - SiHa [nTPM]":"10.9","Cell RNA - SK-BR-3 [nTPM]":"27.2","Cell RNA - SK-MEL-30 [nTPM]":"6.7","Cell RNA - SuSa [nTPM]":"3.9","Cell RNA - T-47d [nTPM]":"14.6","Cell RNA - THP-1 [nTPM]":"12.9","Cell RNA - TIME [nTPM]":"8.0","Cell RNA - U-138 MG [nTPM]":"11.9","Cell RNA - U-2 OS [nTPM]":"4.9","Cell RNA - U-2197 [nTPM]":"8.5","Cell RNA - U-251 MG [nTPM]":"22.7","Cell RNA - U-266\/70 [nTPM]":"10.6","Cell RNA - U-266\/84 [nTPM]":"67.1","Cell RNA - U-698 [nTPM]":"10.7","Cell RNA - U-87 MG [nTPM]":"11.0","Cell RNA - U-937 [nTPM]":"14.0","Cell RNA - WM-115 [nTPM]":"10.4","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"0.7","Blood RNA - eosinophil [nTPM]":"1.1","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"0.7","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"1.0","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"0.8","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"0.9","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"1.6","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"1.7","Blood RNA - T-reg [nTPM]":"2.0","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"4.8","Brain RNA - basal ganglia [nTPM]":"5.0","Brain RNA - cerebellum [nTPM]":"8.2","Brain RNA - cerebral cortex [nTPM]":"6.7","Brain RNA - hippocampal formation [nTPM]":"5.3","Brain RNA - hypothalamus [nTPM]":"4.8","Brain RNA - medulla oblongata [nTPM]":"4.5","Brain RNA - midbrain [nTPM]":"4.5","Brain RNA - pons [nTPM]":"5.0","Brain RNA - spinal cord [nTPM]":"5.0","Brain RNA - thalamus [nTPM]":"5.4","Brain RNA - white matter [nTPM]":"5.6","Single Cell Type RNA - Adipocytes [nTPM]":"7.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.6","Single Cell Type RNA - Astrocytes [nTPM]":"12.1","Single Cell Type RNA - B-cells [nTPM]":"18.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"5.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"5.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"21.9","Single Cell Type RNA - dendritic cells [nTPM]":"7.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"12.9","Single Cell Type RNA - Early spermatids [nTPM]":"1.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.7","Single Cell Type RNA - Endothelial cells [nTPM]":"5.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"9.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"36.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"25.2","Single Cell Type RNA - Fibroblasts [nTPM]":"4.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.9","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"7.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.1","Single Cell Type RNA - Hepatocytes [nTPM]":"7.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.5","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"33.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.4","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"6.5","Single Cell Type RNA - Langerhans cells [nTPM]":"4.8","Single Cell Type RNA - Late spermatids [nTPM]":"3.7","Single Cell Type RNA - Leydig cells [nTPM]":"2.5","Single Cell Type RNA - Macrophages [nTPM]":"7.1","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"18.7","Single Cell Type RNA - monocytes [nTPM]":"6.4","Single Cell Type RNA - Muller glia cells [nTPM]":"7.8","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"29.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"34.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.2","Single Cell Type RNA - Paneth cells [nTPM]":"8.1","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"16.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"12.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.9","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.2","Single Cell Type RNA - Spermatocytes [nTPM]":"2.2","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"34.1","Single Cell Type RNA - T-cells [nTPM]":"7.4","Single Cell Type RNA - Theca cells [nTPM]":"3.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.0","Single Cell Type RNA - Urothelial cells [nTPM]":"4.8"}]