Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ABCB4 "GBD1, MDR2, MDR3, PFIC-3, PGY3" ENSG00000005471 "ATP binding cassette subfamily B member 4" P21439 7 87401696-87480435 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "liver: 123.2" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 256.1" "Cancer enriched" "Detected in some" 11 "liver cancer: 16.3" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 5 "memory B-cell: 4.4;naive B-cell: 8.1" "Lineage enriched" "Detected in many" 7 "B-cells: 8.1" "Group enriched" "Detected in some" 5 "SH-SY5Y: 12.9;WM-115: 25.7" "Low region specificity" "Detected in many" "HPA049395, HPA053288" Enhanced Approved "Nucleoplasm,Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 62: Liver - Hemostasis" "Cluster 17: WM-115 - Nervous system development" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Plasma membrane, Actin filaments" "Focal adhesion sites" "HPA049395: AB_2680745, HPA053288: AB_2682102" "unprognostic (7.92e-2)" "unprognostic (8.87e-2)" "unprognostic (1.97e-1)" "unprognostic (1.90e-1)" "unprognostic (8.95e-2)" "unprognostic (1.06e-2)" "unprognostic (2.35e-3)" "unprognostic (9.91e-2)" "unprognostic (3.53e-1)" "unprognostic (1.19e-1)" "unprognostic (2.44e-3)" "unprognostic (8.43e-2)" "unprognostic (2.83e-2)" "unprognostic (8.01e-3)" "unprognostic (7.12e-2)" "unprognostic (2.11e-2)" "unprognostic (2.47e-1)" 0.7 7.4 0.8 2.5 0.6 0.9 0.5 0.6 0.9 0.3 0.4 1.1 0.4 0.2 0.6 0.6 0.2 0.8 6.6 0.8 0.6 0.6 123.2 0.2 5.9 0.9 0.6 0.4 0.1 0.0 0.2 0.2 1.0 0.5 1.2 0.4 0.6 0.4 7.5 1.4 2.1 0.3 0.6 5.0 0.6 1.0 0.7 0.7 0.5 4.8 5.2 1.2 0.5 0.7 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.4 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.2 12.9 0.0 0.6 2.6 0.5 0.2 0.6 0.0 0.2 1.7 0.1 0.0 0.0 0.0 3.2 0.2 0.0 25.7 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 1.2 8.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.8 0.6 0.6 0.9 0.8 0.6 0.9 0.6 1.0 0.6 0.7 0.7 1.3 0.0 0.5 0.3 22.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 10.2 0.0 0.0 1.8 0.0 1.1 0.1 0.2 0.0 0.1 0.6 0.2 0.2 1.0 0.0 0.4 0.6 0.0 0.3 2.0 0.0 0.2 0.0 0.0 3.3 256.1 0.5 38.7 1.8 0.0 0.0 5.0 1.2 0.4 0.0 1.0 10.6 3.7 0.1 0.0 0.0 0.5 0.0 0.1 0.1 0.4 0.3 0.0 0.5 0.7 0.0 0.2 0.0 0.6 1.2 1.2 0.2 0.0 0.4 0.1 0.7 0.0 0.2 0.0 ABCB6 "EST45597, MTABC3, umat" ENSG00000115657 "ATP binding cassette subfamily B member 6 (Langereis blood group)" Q9NP58 2 219209772-219218994 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant, Dyskeratosis congenita, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 14.7;Excitatory neurons: 12.9;Gastric mucus-secreting cells: 5.1;Inhibitory neurons: 10.9;Oligodendrocyte precursor cells: 13.6;Oligodendrocytes: 5.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 65.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046723, HPA058011" Approved Supported "Nucleoplasm,Golgi apparatus,Plasma membrane,Mitochondria,Cytosol" "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" "Nucleoplasm, Plasma membrane, Mitochondria, Cytosol" "HPA046723: AB_10960288, HPA058011: AB_2683578" "unprognostic (8.04e-2)" "unprognostic (3.22e-2)" "unprognostic (4.53e-3)" "unprognostic (3.19e-2)" "unprognostic (2.55e-1)" "unprognostic (9.11e-2)" "prognostic unfavorable (9.45e-7)" "unprognostic (2.26e-1)" "unprognostic (3.62e-2)" "unprognostic (1.53e-1)" "unprognostic (1.18e-4)" "unprognostic (3.02e-3)" "prognostic unfavorable (1.52e-7)" "unprognostic (1.51e-1)" "unprognostic (9.55e-2)" "unprognostic (7.75e-2)" "unprognostic (2.30e-1)" 10.2 8.7 4.3 3.4 3.9 10.4 7.6 3.2 4.6 7.7 4.4 6.5 6.9 8.4 8.2 11.4 9.6 7.1 8.5 4.0 5.1 5.2 15.9 5.9 1.9 4.4 4.2 12.9 5.7 4.8 6.0 3.1 6.2 8.0 3.3 3.0 6.2 8.6 30.4 6.8 6.3 7.9 4.1 3.9 7.9 18.0 5.7 2.6 10.7 9.8 2.9 14.9 7.9 5.0 0.3 22.9 4.7 28.8 30.8 11.1 27.6 8.5 7.9 9.2 9.2 35.5 5.0 0.3 42.8 8.6 5.0 49.1 0.6 3.6 3.0 15.0 4.7 36.3 24.9 65.8 37.0 0.0 12.0 16.3 4.2 6.2 0.1 13.9 16.3 4.8 31.4 4.4 6.3 12.0 2.3 0.1 7.2 53.6 9.2 12.3 14.3 1.6 5.1 0.4 16.6 17.8 17.6 41.4 18.7 17.4 12.4 0.8 7.5 12.5 0.5 16.9 10.3 11.2 9.6 0.1 14.0 0.4 17.0 0.7 0.4 0.0 0.7 0.4 0.2 1.0 0.5 0.2 0.3 0.8 1.2 0.8 0.0 0.4 0.3 2.3 0.5 1.0 4.3 3.9 3.2 4.6 4.0 5.1 4.4 4.2 6.2 4.1 5.7 5.0 0.2 0.0 0.0 14.7 0.3 0.3 0.0 0.5 1.2 1.0 0.2 0.0 0.2 0.0 1.3 0.0 0.0 0.2 0.2 0.1 0.0 0.8 1.2 0.3 0.6 0.4 0.0 1.3 12.9 0.0 0.1 0.7 5.1 0.2 0.0 0.5 0.0 0.4 0.1 0.0 10.9 0.3 0.0 0.3 0.4 1.0 0.3 0.3 0.0 3.7 0.0 0.3 0.0 13.6 5.6 0.3 0.0 0.4 0.5 0.0 0.5 0.2 2.2 0.8 0.0 0.4 0.3 1.0 0.3 2.8 0.3 0.3 0.1 0.4 0.2 0.1 AC138696.1 ENSG00000264668 "Novel protein" 8 143247110-143276403 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.7;MOLT-4: 1.2" "HPA047232, HPA056268" Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Plasma membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Nucleoli, Nucleoli rim" "Nucleoplasm, Plasma membrane" "HPA047232: , HPA056268: AB_2683082" "unprognostic (2.24e-2)" "unprognostic (2.10e-1)" "unprognostic (3.56e-3)" "unprognostic (1.87e-1)" "unprognostic (8.68e-3)" "unprognostic (1.14e-1)" "unprognostic (1.51e-1)" "unprognostic (9.80e-2)" "unprognostic (4.20e-1)" "unprognostic (3.27e-2)" "unprognostic (1.34e-1)" "unprognostic (1.03e-2)" "unprognostic (2.20e-2)" "unprognostic (3.99e-1)" "unprognostic (2.59e-2)" "unprognostic (4.06e-1)" 0.3 0.3 0.2 0.0 0.3 0.0 0.2 0.1 0.5 0.3 0.0 0.4 0.1 0.6 0.0 0.1 0.7 0.0 0.1 0.3 0.3 0.1 0.1 0.1 0.1 0.2 0.4 0.4 0.6 0.1 0.2 0.0 0.3 0.3 0.0 0.1 0.2 0.2 0.4 0.1 0.3 0.2 0.2 0.1 0.3 0.2 0.3 0.0 0.1 0.0 0.0 0.4 0.1 0.2 0.5 0.0 0.0 0.3 1.7 0.1 0.1 0.5 1.1 0.6 0.2 0.0 0.7 0.0 0.3 0.1 0.1 0.2 0.0 0.2 0.2 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.2 1.0 0.4 0.0 0.3 0.2 0.3 0.4 0.0 0.0 0.0 0.0 1.2 0.0 1.1 0.1 0.3 0.6 1.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.3 0.3 0.0 0.0 0.2 1.1 0.0 0.8 0.2 0.5 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.3 0.1 0.5 0.3 0.3 0.2 0.4 0.3 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ADAMTS16 ADAMTS16s ENSG00000145536 "ADAM metallopeptidase with thrombospondin type 1 motif 16" Q8TE57 5 5140330-5320304 "Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.0;ovary: 10.4" "Cell type enhanced" "Detected in some" "Collecting duct cells: 7.3;Excitatory neurons: 44.7;Fibroblasts: 13.7;Granulosa cells: 22.2;Theca cells: 15.9" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 5 "cerebellum: 17.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 3.9;SuSa: 3.5;U-2197: 5.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA067668 Approved "Nucleoplasm,Nuclear membrane,Midbody ring,Mitochondria" "Secreted to extracellular matrix" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear membrane, Mitochondria" "Nucleoplasm, Midbody ring" "HPA067668: " "unprognostic (8.48e-2)" "unprognostic (1.19e-1)" "unprognostic (2.86e-2)" "unprognostic (1.98e-4)" "unprognostic (1.91e-2)" "unprognostic (5.04e-2)" "unprognostic (7.64e-2)" "unprognostic (7.80e-3)" "unprognostic (2.12e-2)" "unprognostic (5.44e-2)" "unprognostic (1.51e-2)" "unprognostic (2.18e-1)" "prognostic favorable (3.29e-5)" "unprognostic (1.20e-4)" "unprognostic (1.46e-1)" "unprognostic (4.59e-3)" "unprognostic (2.86e-3)" 5.4 0.2 1.4 0.4 1.9 0.5 0.7 17.0 2.6 1.4 0.0 0.7 0.6 1.3 1.6 1.5 0.7 6.4 0.2 3.4 0.0 3.5 0.4 0.7 0.2 0.2 0.2 10.4 4.5 0.1 0.0 0.2 0.7 0.1 0.3 1.2 0.2 0.5 0.2 0.4 0.5 1.1 0.0 0.2 0.2 0.4 0.0 0.2 0.3 0.2 0.1 1.0 0.6 1.8 1.7 1.7 1.7 0.1 0.1 0.3 0.2 0.0 0.0 0.4 0.5 0.0 1.4 0.1 2.1 0.0 3.0 0.1 0.0 0.0 0.4 0.1 0.9 0.3 2.8 0.0 0.0 0.2 0.0 0.0 0.0 3.9 0.1 0.5 0.0 0.3 0.6 0.4 0.7 0.0 0.4 0.2 1.1 0.0 1.6 0.4 2.2 0.1 0.0 0.1 0.5 0.1 0.1 0.1 0.1 3.5 0.1 0.1 0.1 2.1 3.0 5.8 1.4 0.9 0.3 0.1 3.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.4 1.9 17.0 2.6 3.4 0.0 0.2 0.2 0.7 0.0 0.0 1.8 0.7 0.0 0.6 2.6 0.0 0.0 0.0 0.0 0.6 2.0 0.7 0.4 0.5 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.2 5.0 0.1 0.0 0.0 44.7 0.0 0.0 13.7 0.5 0.5 0.0 22.2 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 2.8 0.0 0.0 0.0 1.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.7 0.0 6.9 1.6 0.1 0.0 0.0 0.0 0.0 0.1 15.9 0.0 0.0 AKR1C2 "BABP, DD, DD2, DDH2, HAKRD, MCDR2, TDD" ENSG00000151632 "Aldo-keto reductase family 1 member C2" P52895 10 4987400-5018031 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 341.5;liver: 481.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 141.7;Club cells: 128.8;Gastric mucus-secreting cells: 133.5;Hepatocytes: 397.4;Urothelial cells: 271.9" "Group enriched" "Detected in many" 6 "cervical cancer: 21.7;head and neck cancer: 31.5;liver cancer: 50.2;lung cancer: 69.0;urothelial cancer: 35.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "A549: 2054.8;ASC diff: 2439.5;Hep G2: 3926.2;OE19: 2684.9;RT4: 1178.9" "CAB047304, HPA068265" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol" NA NA "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center, Endoplasmic reticulum" "CAB047304: , HPA068265: AB_2685966" "unprognostic (6.77e-2)" "unprognostic (8.88e-3)" "unprognostic (3.02e-2)" "unprognostic (2.24e-1)" "unprognostic (1.31e-1)" "unprognostic (1.72e-2)" "unprognostic (2.86e-2)" "unprognostic (8.65e-2)" "unprognostic (5.03e-2)" "unprognostic (2.58e-1)" "unprognostic (1.02e-1)" "unprognostic (6.25e-3)" "unprognostic (8.58e-2)" "unprognostic (1.09e-2)" "unprognostic (8.60e-3)" "unprognostic (1.46e-2)" "unprognostic (8.30e-2)" 341.5 20.8 9.8 10.0 11.6 1.0 205.6 10.7 12.9 17.4 8.1 37.1 29.6 5.6 3.3 202.5 8.6 98.1 83.8 7.2 16.6 43.0 481.9 23.5 2.1 18.7 13.7 10.4 11.8 1.1 8.1 0.8 17.1 11.7 13.3 15.2 116.5 12.9 286.9 42.5 33.7 9.2 11.5 2.1 137.0 11.8 16.8 4.4 38.3 36.5 9.3 253.9 47.0 9.7 0.0 2054.8 2.4 214.1 2439.5 83.4 0.1 0.7 8.6 0.9 2.0 8.1 0.2 0.4 11.5 14.2 10.0 57.8 0.2 10.7 1.2 0.6 0.2 0.7 516.4 3926.2 4.6 0.4 0.9 218.3 126.4 10.5 10.4 0.7 0.9 0.3 81.9 0.3 20.4 3.3 0.2 0.0 0.7 2684.9 0.8 0.3 0.6 34.6 19.0 1178.9 1.2 0.4 21.2 0.3 0.1 0.4 0.5 4.0 8.6 5.1 1.8 74.6 0.8 0.6 0.6 0.3 25.9 30.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.8 11.6 10.7 12.9 7.2 16.6 18.7 13.7 17.1 11.5 16.8 9.7 15.2 12.8 2.8 0.0 0.9 11.9 9.5 141.7 20.5 1.9 0.8 1.4 5.5 102.9 128.8 0.0 0.0 0.0 0.0 10.3 0.0 18.3 17.3 0.7 0.5 7.5 1.8 8.0 2.6 103.3 0.1 44.2 133.5 0.8 0.0 0.1 10.8 397.4 0.1 3.3 4.2 5.4 46.8 12.0 7.8 7.8 79.2 1.0 8.8 19.7 0.6 39.6 0.0 5.5 0.3 90.0 6.6 78.6 0.8 23.7 15.9 3.6 40.3 3.0 0.0 5.3 13.9 0.2 0.3 112.9 13.5 0.0 1.3 0.4 8.5 271.9 AKR1C3 "DDX, HAKRB, HSD17B5, KIAA0119, PGFS" ENSG00000196139 "Aldo-keto reductase family 1 member C3" P42330 10 5035354-5107686 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 441.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 393.1;Exocrine glandular cells: 722.5;Proximal enterocytes: 576.9;Proximal tubular cells: 601.8" "Cancer enhanced" "Detected in all" "liver cancer: 83.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 244.0;gdT-cell: 102.6" "Group enriched" "Detected in many" 4 "granulocytes: 244.0;T-cells: 102.6" "Cell line enhanced" "Detected in many" "A549: 1615.1;ASC diff: 811.9;Hep G2: 699.6;OE19: 3025.3;RT4: 639.2" "CAB010874, HPA068265" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol" NA NA 19000000 "Cluster 38: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center, Endoplasmic reticulum" "CAB010874: AB_476751, HPA068265: AB_2685966" "unprognostic (4.20e-3)" "unprognostic (2.70e-2)" "unprognostic (8.92e-2)" "unprognostic (1.53e-1)" "unprognostic (1.05e-1)" "unprognostic (1.81e-3)" "prognostic unfavorable (1.96e-4)" "unprognostic (1.41e-1)" "unprognostic (6.74e-2)" "unprognostic (5.08e-2)" "unprognostic (1.31e-1)" "unprognostic (4.33e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (4.45e-1)" "unprognostic (3.70e-2)" "unprognostic (1.79e-3)" "unprognostic (4.24e-3)" 164.4 50.2 31.1 25.4 34.6 42.3 115.2 32.1 42.4 21.9 30.2 185.9 441.3 25.9 4.4 53.2 42.1 261.1 42.9 31.5 35.6 177.7 268.0 48.3 7.6 30.3 33.9 17.8 36.4 22.5 10.4 4.7 32.3 10.3 98.0 19.1 40.5 19.4 116.9 27.0 270.9 39.2 30.3 3.8 237.4 10.0 31.5 37.4 26.4 34.8 6.6 84.7 22.2 31.1 0.1 1615.1 1.1 413.0 811.9 292.2 1.0 0.0 21.4 0.4 1.4 47.6 24.5 0.2 78.7 19.4 45.0 11.5 1.5 28.8 1.1 3.0 0.5 3.2 438.4 699.6 4.3 0.7 0.2 160.9 57.1 20.0 0.7 25.8 28.1 3.4 10.8 0.0 42.6 3.8 9.8 2.6 0.7 3025.3 4.3 3.3 9.6 43.7 149.0 639.2 1.0 2.9 232.2 0.0 0.3 0.9 0.5 0.2 221.7 5.2 4.7 87.8 3.1 0.7 0.7 0.3 45.8 62.8 4.4 244.0 2.9 4.8 102.6 0.9 6.9 0.0 19.0 18.7 2.1 0.5 11.6 8.9 7.3 21.1 1.4 39.6 21.4 42.4 31.1 34.6 32.1 42.4 31.5 35.6 30.3 33.9 32.3 30.3 31.5 31.1 144.2 44.8 5.3 4.9 4.3 12.0 3.7 393.1 2.8 2.0 15.8 5.5 3.9 0.0 172.9 36.8 0.0 0.4 64.4 133.8 43.0 114.6 3.3 67.5 4.5 67.5 19.2 34.9 2.5 722.5 0.0 44.3 158.0 66.4 5.7 0.1 0.0 0.0 1.6 1.7 3.2 65.9 61.1 0.0 14.0 4.9 78.3 14.8 21.4 7.5 4.1 132.7 202.9 14.6 0.0 266.1 219.6 106.8 3.1 1.3 576.9 601.8 112.8 5.3 26.3 15.5 20.3 0.5 4.3 20.2 10.7 0.0 14.4 7.8 196.9 46.4 AKR1C4 "3-alpha-HSD, C11, CDR, CHDR, DD4, HAKRA, MGC22581" ENSG00000198610 "Aldo-keto reductase family 1 member C4" P17516 10 5195462-5218949 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "liver: 717.5" "Cell type enriched" "Detected in some" 16 "Hepatocytes: 613.3" "Cancer enriched" "Detected in some" 86 "liver cancer: 108.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HDLM-2: 6.6;OE19: 2.9" "HPA044720, HPA068265" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol" NA NA 3800000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center, Endoplasmic reticulum" "HPA044720: AB_2679058, HPA068265: AB_2685966" "unprognostic (2.21e-1)" "unprognostic (3.04e-1)" "unprognostic (5.15e-2)" "unprognostic (1.25e-1)" "unprognostic (5.99e-2)" "unprognostic (9.40e-2)" "unprognostic (2.32e-1)" "unprognostic (1.26e-1)" "unprognostic (1.52e-2)" "unprognostic (1.29e-1)" "unprognostic (3.31e-1)" "unprognostic (7.34e-2)" "unprognostic (1.45e-2)" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.5 0.0 0.2 0.0 0.4 41.8 0.0 0.0 0.0 0.3 717.5 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 1.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.3 0.2 1.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.9 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 37.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 7.2 0.2 0.0 0.8 0.0 13.5 0.0 0.7 0.0 0.7 0.0 0.0 0.0 0.0 13.6 613.3 0.0 0.0 0.0 0.6 0.0 14.5 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.2 1.0 1.5 0.0 0.0 0.1 0.0 2.1 0.4 0.0 0.0 0.0 0.8 0.0 0.0 0.1 ALDH3A1 ALDH3 ENSG00000108602 "Aldehyde dehydrogenase 3 family member A1" P30838 17 19737984-19748943 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 496.1;salivary gland: 128.0;stomach 1: 224.8" "Group enriched" "Detected in many" 4 "Basal respiratory cells: 389.5;Basal squamous epithelial cells: 274.3;Club cells: 150.1;Gastric mucus-secreting cells: 437.9;Respiratory ciliated cells: 412.7;Squamous epithelial cells: 342.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 64.4;lung cancer: 60.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 23 "A549: 5094.7;OE19: 6071.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB045957, HPA051150, HPA063783" Enhanced Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" No No 52000 "Cluster 22: NK-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "Nucleoplasm, Vesicles" "CAB045957: AB_11127164, HPA051150: AB_2681364, HPA063783: AB_2685122" "unprognostic (3.11e-5)" "unprognostic (1.20e-2)" "unprognostic (1.08e-1)" "unprognostic (7.04e-3)" "unprognostic (4.36e-3)" "prognostic favorable (7.55e-5)" "unprognostic (3.12e-1)" "unprognostic (3.84e-1)" "unprognostic (2.10e-1)" "unprognostic (1.67e-1)" "unprognostic (2.69e-3)" "unprognostic (5.54e-2)" "unprognostic (1.72e-1)" "unprognostic (3.84e-2)" "unprognostic (1.83e-1)" "unprognostic (2.88e-2)" "unprognostic (7.23e-2)" 1.7 1.0 0.4 1.3 0.7 0.1 3.2 0.3 0.4 6.7 17.5 4.5 6.2 0.3 0.2 496.1 5.5 10.3 0.3 1.0 0.4 1.3 1.9 10.9 0.5 0.6 2.1 0.4 0.5 0.0 0.9 0.0 0.5 1.9 3.3 0.1 128.0 1.5 1.3 72.6 3.5 0.4 0.9 0.9 224.8 1.6 1.3 0.6 0.5 0.3 33.7 6.2 22.3 0.9 0.1 5094.7 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.2 10.7 246.5 0.0 2.7 0.5 2.0 29.3 0.7 12.8 0.0 0.0 0.8 0.1 116.6 1.0 0.3 0.1 0.5 0.0 14.9 0.5 0.4 0.2 0.5 0.0 0.0 0.0 0.0 9.7 0.1 0.3 0.4 6071.6 19.8 0.0 0.0 0.0 0.0 87.0 0.2 0.6 24.8 0.0 0.0 0.2 0.2 0.9 0.6 0.3 0.8 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.7 0.3 0.4 1.0 0.4 0.6 2.1 0.5 0.9 1.3 0.9 0.7 3.2 5.5 0.0 0.7 44.1 46.8 389.5 274.3 0.0 0.1 1.5 0.4 2.8 150.1 0.0 0.0 0.0 0.0 5.1 0.0 1.4 1.5 12.4 0.2 1.3 1.8 0.0 0.1 0.5 0.0 1.6 437.9 0.8 2.5 0.3 1.4 3.2 0.2 0.0 0.0 4.8 83.4 0.3 1.8 5.2 0.9 1.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 9.5 4.7 1.9 3.2 5.8 3.4 5.0 412.7 0.2 0.0 1.7 20.1 1.7 8.6 342.2 32.0 0.0 0.5 0.2 8.4 64.3 ALDOC ENSG00000109107 "Aldolase, fructose-bisphosphate C" P09972 17 28573115-28576948 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis Lyase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1384.6;choroid plexus: 589.6;retina: 1183.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 112.5;Horizontal cells: 274.2;Muller glia cells: 127.1;Proximal enterocytes: 120.0;Rod photoreceptor cells: 348.5" "Cancer enriched" "Detected in all" 6 "glioma: 128.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 250.9;U-266/70: 161.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003282, CAB020828, HPA067442" Enhanced Supported Approved "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" Yes No 150000000 "Cluster 20: T-cells - T-cell receptor" "Cluster 77: Retina - Visual perception" "Cluster 25: RPMI-8226 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Nucleoli fibrillar center" "Vesicles, Cytosol" "CAB020828: , HPA003282: AB_1078130, HPA067442: " "unprognostic (2.90e-1)" "unprognostic (4.45e-3)" "unprognostic (5.69e-3)" "unprognostic (1.43e-1)" "unprognostic (3.56e-1)" "prognostic unfavorable (9.80e-4)" "unprognostic (1.03e-1)" "unprognostic (1.70e-1)" "unprognostic (1.30e-1)" "unprognostic (6.03e-3)" "unprognostic (3.90e-1)" "unprognostic (3.24e-2)" "prognostic unfavorable (1.29e-7)" "unprognostic (1.28e-1)" "unprognostic (2.00e-1)" "unprognostic (2.74e-2)" "unprognostic (1.23e-1)" 87.0 24.3 953.6 12.7 909.7 23.6 42.5 1238.3 1162.3 39.3 589.6 18.5 18.7 17.9 10.9 40.8 14.3 10.9 285.5 955.7 958.0 16.8 98.3 13.7 19.3 1297.5 962.6 39.1 4.9 12.1 30.6 4.1 1384.6 18.9 14.7 1183.1 19.9 15.8 4.8 74.5 43.9 12.4 926.9 24.4 23.3 14.2 1090.2 9.6 7.4 8.1 30.5 19.0 47.0 886.1 29.9 2.1 13.7 55.7 29.9 32.9 2.9 16.7 37.7 12.9 76.0 17.9 3.0 14.9 17.3 15.5 3.3 36.9 10.3 102.3 23.4 12.4 8.9 28.3 11.6 30.4 25.8 10.0 29.2 27.8 13.9 1.5 24.0 1.7 5.3 29.7 19.3 71.9 10.7 15.1 11.9 32.0 20.8 6.7 15.3 9.5 1.6 250.9 1.9 4.3 36.2 61.9 9.1 67.3 0.5 20.8 36.6 21.2 3.5 1.2 5.3 2.1 2.4 161.0 51.4 10.9 105.2 28.0 1.9 0.5 7.4 3.0 21.6 8.7 30.6 24.0 29.5 17.8 9.4 25.1 37.7 28.4 18.0 29.4 5.3 4.6 40.9 19.0 953.6 909.7 1238.3 1162.3 955.7 958.0 1297.5 962.6 1384.6 926.9 1090.2 886.1 4.2 0.0 15.8 97.6 9.8 7.5 20.3 80.5 8.6 112.5 9.0 11.0 22.1 11.5 29.3 7.3 106.3 1.1 9.5 31.7 3.9 21.9 0.9 1.0 3.0 11.3 21.6 3.2 19.2 10.2 6.5 5.8 6.6 1.2 13.3 4.9 14.3 93.1 5.4 274.2 41.3 12.9 28.5 4.4 5.3 1.3 9.3 3.1 24.9 21.5 34.1 127.1 12.3 26.7 16.8 12.4 12.4 10.1 2.6 6.1 120.0 2.1 11.8 348.5 13.1 6.4 10.1 0.3 3.2 7.9 10.9 1.5 17.0 11.7 5.1 7.8 ANKRD31 FLJ40191 ENSG00000145700 "Ankyrin repeat domain 31" Q8N7Z5 5 75068275-75236911 "Predicted intracellular proteins" "DNA recombination, Meiosis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "testis: 4.9" "Group enriched" "Detected in some" 7 "Spermatocytes: 148.9;Spermatogonia: 37.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA038028, HPA057566" Enhanced Approved Nucleoplasm,Nucleoli,Vesicles,Centrosome NA NA "Cluster 35: T-regs - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Centrosome" "Nucleoli, Vesicles" "HPA038028: AB_10672615, HPA057566: AB_2683470" "unprognostic (1.37e-1)" "unprognostic (4.28e-2)" "unprognostic (5.25e-2)" "unprognostic (5.57e-2)" "unprognostic (1.65e-1)" "unprognostic (5.72e-2)" "unprognostic (4.81e-2)" "unprognostic (2.52e-2)" "unprognostic (3.63e-1)" "unprognostic (1.83e-1)" "unprognostic (1.02e-2)" "unprognostic (1.69e-1)" "unprognostic (3.00e-2)" "unprognostic (4.46e-2)" "unprognostic (5.48e-2)" "unprognostic (1.24e-2)" "unprognostic (1.40e-1)" 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.3 0.0 0.0 0.1 0.1 0.1 0.7 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.2 0.3 0.2 0.1 0.2 0.1 0.0 0.2 0.1 0.0 0.3 0.2 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.0 4.9 0.1 0.2 0.0 0.0 0.0 0.0 0.4 0.3 0.2 0.1 0.1 0.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.1 0.0 0.3 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.2 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.3 0.2 0.2 0.1 0.3 0.1 0.0 0.5 5.2 0.4 0.4 0.4 0.5 0.6 3.3 0.8 1.1 1.1 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.3 3.6 2.8 0.8 0.1 0.0 0.8 5.8 0.2 0.6 0.4 4.1 0.4 12.0 0.5 0.4 0.0 0.1 1.7 5.4 0.0 0.0 0.0 0.0 4.7 1.5 0.1 0.0 1.0 0.1 1.3 0.0 3.0 5.6 0.1 0.1 0.4 1.3 0.0 0.1 0.3 1.2 2.2 13.1 0.6 0.4 148.9 37.7 0.4 0.1 0.3 1.1 0.7 0.1 0.2 ARAP1 CENTD2 ENSG00000186635 "ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1" Q96P48 11 72685069-72793599 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020703, HPA070383" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA 36000 "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "CAB020703: , HPA070383: AB_2686262" "unprognostic (3.60e-2)" "unprognostic (7.68e-2)" "unprognostic (6.19e-2)" "unprognostic (5.98e-2)" "unprognostic (5.76e-2)" "unprognostic (1.64e-2)" "prognostic unfavorable (6.45e-4)" "unprognostic (4.01e-2)" "unprognostic (4.07e-1)" "unprognostic (5.95e-2)" "prognostic favorable (2.04e-5)" "unprognostic (1.84e-1)" "unprognostic (1.05e-3)" "unprognostic (6.93e-2)" "unprognostic (2.57e-2)" "prognostic favorable (6.41e-4)" "unprognostic (7.56e-3)" 41.5 63.5 40.0 58.6 48.6 97.5 33.4 37.9 50.4 44.1 62.9 35.5 29.6 38.9 14.0 37.7 48.3 44.2 42.9 42.2 38.5 47.8 40.2 71.8 53.4 50.6 42.3 49.4 37.1 20.4 48.9 35.5 45.9 44.9 18.2 8.6 33.3 25.7 20.1 47.1 43.3 28.7 40.1 117.5 31.3 16.4 50.8 32.2 46.6 20.1 25.2 39.7 37.5 56.8 19.7 41.9 15.2 18.5 63.4 42.9 23.1 26.2 46.5 29.8 29.3 56.0 50.8 42.9 51.3 44.4 40.7 64.5 23.2 64.4 12.5 50.9 28.4 36.6 40.3 81.9 43.7 25.1 98.7 47.5 65.4 48.7 23.4 36.2 33.2 31.3 31.5 17.4 13.9 40.3 38.9 89.3 9.5 35.1 25.9 36.8 23.2 21.3 27.5 61.1 15.7 32.0 19.1 27.9 84.8 19.5 25.1 56.8 37.5 41.0 28.5 42.8 16.4 27.4 14.3 23.0 21.8 37.4 22.3 19.3 24.8 30.7 8.9 39.4 5.2 6.6 5.9 6.8 15.9 4.7 4.5 5.4 50.8 13.4 51.3 5.3 6.7 17.6 40.0 48.6 37.9 50.4 42.2 38.5 50.6 42.3 45.9 40.1 50.8 56.8 8.9 28.9 32.3 33.6 16.1 7.4 7.5 14.3 15.4 4.3 8.7 7.9 2.6 7.2 9.0 16.5 33.3 9.2 18.3 16.5 9.8 13.5 50.1 14.1 11.7 7.8 23.3 9.9 7.7 7.5 8.9 22.4 16.3 9.1 10.8 36.9 9.7 10.8 43.0 0.0 7.0 12.8 12.2 45.6 25.1 6.4 20.8 57.3 8.8 30.0 29.0 7.4 21.6 17.6 31.5 12.1 10.9 15.1 12.3 4.8 20.9 5.3 20.2 2.8 0.0 8.6 8.8 0.4 2.8 10.8 5.4 4.9 12.4 10.5 15.1 7.4 ARHGAP29 PARG1 ENSG00000137962 "Rho GTPase activating protein 29" Q52LW3 1 94148988-94275068 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 440.8;Endothelial cells: 298.6;Prostatic glandular cells: 593.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.1" "Lineage enriched" "Detected in single" 12 "monocytes: 1.1" "Cell line enhanced" "Detected in many" "A-431: 118.8;hTERT-HME1: 100.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026534 Approved Approved "Nucleoplasm,Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Centrosome" "Plasma membrane, Cytosol" "HPA026534: AB_1844998" "unprognostic (2.49e-1)" "unprognostic (1.52e-3)" "unprognostic (3.16e-2)" "prognostic unfavorable (6.26e-5)" "unprognostic (8.53e-2)" "unprognostic (2.94e-2)" "unprognostic (1.23e-1)" "unprognostic (1.11e-1)" "unprognostic (8.02e-2)" "unprognostic (2.89e-2)" "prognostic unfavorable (9.63e-4)" "unprognostic (4.42e-1)" "unprognostic (2.36e-2)" "unprognostic (3.81e-3)" "unprognostic (1.94e-1)" "unprognostic (1.13e-1)" "unprognostic (4.61e-3)" 32.9 3.7 7.0 2.8 5.5 0.1 30.3 22.5 8.0 8.8 7.3 9.4 2.1 7.4 5.3 4.5 10.2 6.5 19.2 4.6 5.5 23.7 16.8 27.1 4.9 6.8 6.1 10.2 7.4 6.5 6.2 17.4 7.1 11.2 3.2 14.9 12.1 7.0 11.6 14.7 6.4 5.6 6.4 21.7 10.4 5.8 8.6 3.0 22.8 12.7 2.8 8.0 9.3 5.1 118.8 4.8 7.0 0.1 26.7 57.5 24.5 38.6 62.9 31.0 45.1 13.7 5.4 0.0 85.2 76.5 36.3 24.8 0.2 27.4 63.9 0.1 4.1 0.4 6.6 7.6 2.7 0.0 0.0 11.7 5.4 23.7 100.9 36.4 88.0 0.1 0.0 0.0 32.1 4.7 2.2 0.1 9.0 0.6 82.1 1.4 5.6 0.0 82.7 10.8 0.1 1.5 24.1 20.5 2.0 26.5 5.6 0.4 84.2 20.0 26.2 29.7 32.3 0.1 0.1 0.2 3.7 0.0 0.9 0.0 0.4 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 7.0 5.5 22.5 8.0 4.6 5.5 6.8 6.1 7.1 6.4 8.6 5.1 440.8 51.3 18.4 26.4 2.9 23.5 239.2 31.7 4.6 16.0 87.3 46.1 26.0 31.5 39.6 130.6 18.8 29.5 2.0 0.9 54.8 83.5 94.1 36.9 11.4 298.6 0.0 3.2 11.3 17.2 102.6 63.6 20.9 106.2 3.8 13.8 177.1 56.1 3.0 92.5 24.1 1.0 6.1 13.6 17.9 24.4 24.5 6.2 26.6 208.9 2.5 94.2 0.0 2.0 3.5 55.7 0.1 21.8 0.1 593.9 0.1 78.1 12.5 81.2 190.7 58.2 127.8 80.3 116.5 1.7 17.2 14.1 4.1 11.1 1.6 146.9 ARHGAP39 "CrGAP, KIAA1688, Vilse" ENSG00000147799 "Rho GTPase activating protein 39" Q9C0H5 8 144529179-144605816 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 21.8" "Cell type enhanced" "Detected in many" "Astrocytes: 34.3;Endometrial ciliated cells: 31.4;Excitatory neurons: 41.7;Inhibitory neurons: 33.1;Oligodendrocytes: 30.8;Respiratory ciliated cells: 27.6;Rod photoreceptor cells: 24.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MCF7: 13.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044491 Approved "Nucleoplasm,Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 43: Testis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "Nucleoplasm, Microtubules, Cytokinetic bridge" "HPA044491: AB_10794775" "unprognostic (3.42e-2)" "unprognostic (2.65e-2)" "unprognostic (9.85e-2)" "unprognostic (4.17e-1)" "unprognostic (1.53e-1)" "unprognostic (2.49e-1)" "unprognostic (1.74e-7)" "unprognostic (1.89e-2)" "unprognostic (3.00e-1)" "unprognostic (2.02e-1)" "unprognostic (6.90e-3)" "unprognostic (1.53e-1)" "unprognostic (5.19e-2)" "unprognostic (1.26e-2)" "unprognostic (1.42e-1)" "unprognostic (1.27e-1)" "unprognostic (9.97e-2)" 1.6 3.9 4.3 0.8 5.2 0.0 3.4 2.3 9.4 4.9 1.2 4.5 1.7 2.8 0.8 5.0 8.2 0.7 1.9 8.5 2.3 4.9 1.6 2.7 0.3 8.4 5.9 2.6 5.2 1.3 9.9 0.7 5.5 4.2 0.6 3.1 3.5 1.4 0.7 5.2 2.7 0.5 4.7 1.3 2.0 21.8 3.5 0.7 7.5 0.1 0.1 1.9 3.1 9.5 8.3 8.1 3.8 5.8 0.7 0.6 7.2 2.1 0.7 2.6 1.6 5.2 4.8 0.8 5.4 0.8 2.7 7.0 1.8 2.0 0.5 0.0 7.2 0.1 5.8 3.4 1.3 0.0 0.8 0.5 3.2 3.3 1.4 1.3 0.8 0.4 7.7 0.0 1.1 13.4 4.6 0.0 4.0 3.4 11.4 4.3 3.0 3.2 2.1 4.1 10.9 7.7 6.2 2.1 3.8 1.4 9.0 1.2 2.0 1.9 0.1 6.6 4.5 0.0 0.1 0.3 3.3 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 5.2 2.3 9.4 8.5 2.3 8.4 5.9 5.5 4.7 3.5 9.5 0.8 3.2 2.3 34.3 0.6 3.7 0.6 1.9 2.2 7.2 5.0 3.3 1.6 0.0 2.8 3.7 20.9 0.6 0.1 7.5 0.0 2.4 3.9 31.4 2.8 1.1 0.0 0.0 41.7 2.5 0.9 1.2 1.1 6.0 0.0 6.0 0.7 1.4 0.5 3.3 33.1 4.2 4.1 0.0 0.4 3.1 2.1 0.2 5.4 1.0 0.0 3.6 0.0 15.6 30.8 1.4 7.9 8.2 0.0 1.0 3.3 1.5 27.6 24.5 6.6 2.5 2.1 8.5 11.2 2.1 3.0 0.5 0.3 3.1 5.2 0.7 ARHGAP40 "C20orf95, dJ1100H13.4" ENSG00000124143 "Rho GTPase activating protein 40" Q5TG30 20 38601934-38651035 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "breast: 32.4;epididymis: 35.7;esophagus: 28.7;skin 1: 45.3" "Cell type enhanced" "Detected in some" "Breast glandular cells: 14.7;Breast myoepithelial cells: 8.6;Club cells: 4.3;Collecting duct cells: 3.7;Early spermatids: 7.2;Late spermatids: 4.3;Respiratory ciliated cells: 3.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 8.3;HBEC3-KT: 13.6;RPTEC TERT1: 11.7;SK-BR-3: 12.7;T-47d: 15.4" "Not detected" "Not detected" "HPA042636, HPA042840" Uncertain Supported "Nucleoplasm,Plasma membrane,Centrosome,Cytosol" No NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 35: Glandular cells - Unknown function" "Plasma membrane, Cytosol" "Nucleoplasm, Centrosome" "HPA042636: AB_10962149, HPA042840: AB_10963929" "unprognostic (9.89e-3)" "unprognostic (2.57e-1)" "unprognostic (1.93e-1)" "unprognostic (1.24e-3)" "unprognostic (3.11e-2)" "unprognostic (1.89e-1)" "unprognostic (2.50e-3)" "unprognostic (1.69e-1)" "unprognostic (3.09e-2)" "unprognostic (4.35e-2)" "unprognostic (5.63e-3)" "unprognostic (2.52e-1)" "prognostic unfavorable (2.89e-4)" "unprognostic (2.24e-1)" "unprognostic (7.42e-2)" "unprognostic (1.26e-1)" "unprognostic (1.54e-1)" 0.1 0.0 0.3 0.0 1.3 0.0 32.4 0.1 0.6 3.2 0.2 0.0 1.7 0.7 35.7 28.7 0.1 0.1 0.0 0.2 0.3 5.6 0.1 0.8 0.0 0.3 1.8 0.0 0.3 0.0 0.0 0.0 0.8 4.6 0.0 0.0 3.6 7.9 0.4 45.3 0.0 0.0 0.2 0.0 4.6 2.7 0.6 0.0 0.9 0.0 3.7 3.2 7.4 0.2 4.5 0.0 0.0 0.0 0.0 0.0 8.3 0.1 0.0 0.0 0.1 0.2 0.9 0.0 3.6 0.0 0.0 0.0 0.0 13.6 0.2 0.0 0.0 0.2 0.0 3.4 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.5 0.5 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 12.7 0.0 1.6 15.4 0.5 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.3 0.1 0.6 0.2 0.3 0.3 1.8 0.8 0.2 0.6 0.2 0.1 0.0 1.5 0.7 0.0 0.3 0.0 1.8 0.0 0.0 14.7 8.6 0.1 0.0 4.3 3.7 0.0 0.0 0.2 0.0 0.0 0.0 7.2 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.0 0.7 0.0 0.4 3.4 0.0 0.0 0.0 0.3 0.7 2.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 ARID5B "FLJ21150, MRF2" ENSG00000150347 "AT-rich interaction domain 5B" Q14865 10 61901684-62096944 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 87.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 968.2;Syncytiotrophoblasts: 920.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 115.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015037 Uncertain Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Endoplasmic reticulum" "Nucleoplasm, Plasma membrane, Cytosol" "HPA015037: AB_1845015" "unprognostic (3.31e-1)" "unprognostic (1.99e-2)" "unprognostic (2.94e-2)" "unprognostic (1.86e-1)" "unprognostic (1.17e-1)" "unprognostic (5.60e-2)" "unprognostic (1.50e-2)" "unprognostic (4.90e-2)" "unprognostic (3.90e-1)" "unprognostic (6.03e-2)" "unprognostic (1.97e-1)" "unprognostic (5.75e-1)" "unprognostic (1.20e-2)" "unprognostic (1.15e-1)" "unprognostic (2.58e-1)" "unprognostic (1.94e-1)" "unprognostic (3.93e-2)" 50.0 8.1 2.9 21.2 5.8 6.9 34.3 3.2 11.3 37.2 20.7 17.5 10.2 39.0 4.6 20.2 20.6 39.3 18.3 4.4 1.6 21.4 8.3 18.3 18.8 7.8 6.9 17.5 6.2 13.3 10.0 21.0 11.4 18.3 11.7 4.1 15.8 10.2 87.2 18.1 14.2 42.5 0.9 16.9 11.5 6.9 9.0 13.1 7.8 11.9 16.7 30.9 19.6 9.7 2.2 0.9 6.0 14.7 13.0 34.0 1.2 42.9 115.2 29.9 23.3 52.7 2.3 3.9 10.1 41.4 4.3 14.3 20.6 6.5 36.0 13.7 6.1 2.1 10.4 13.5 23.9 0.6 25.2 43.3 3.4 17.6 20.2 26.2 3.9 7.5 1.9 5.7 9.9 7.7 14.4 1.1 1.1 10.2 13.5 17.7 9.8 1.1 20.1 23.9 3.3 4.4 19.2 10.6 12.8 13.1 8.7 0.7 3.3 16.5 22.0 25.1 10.9 0.4 0.0 11.4 14.3 0.8 5.4 9.6 1.2 0.8 13.3 2.8 1.8 37.5 19.7 11.8 2.2 41.2 12.8 8.4 2.2 12.3 8.2 1.0 30.9 5.4 2.9 5.8 3.2 11.3 4.4 1.6 7.8 6.9 11.4 0.9 9.0 9.7 86.2 131.4 70.7 54.5 199.8 968.2 453.9 111.3 105.9 54.4 112.8 96.6 72.8 27.1 96.3 51.5 0.0 187.8 89.1 7.5 99.7 56.1 31.7 164.7 231.0 134.1 36.4 5.2 167.8 14.6 150.7 343.6 21.4 457.7 24.6 37.6 119.2 7.4 51.0 74.0 181.9 18.7 22.4 44.1 162.4 20.1 151.6 43.6 138.7 34.7 39.0 17.2 58.7 74.4 155.8 41.1 25.2 60.5 234.5 193.7 5.4 304.8 38.4 3.6 131.5 496.3 463.9 8.2 5.8 65.7 477.8 920.4 178.2 24.3 41.7 233.9 ARL14EP "ARF7EP, C11orf46, FLJ38968" ENSG00000152219 "ADP ribosylation factor like GTPase 14 effector protein" Q8N8R7 11 30323104-30338223 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 130.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039634, HPA048127" Approved Supported "Nucleoplasm,Vesicles,Focal adhesion sites,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" "Vesicles, Focal adhesion sites, Cytosol" Nucleoplasm "HPA039634: AB_2676606, HPA048127: AB_2680277" "prognostic favorable (2.50e-5)" "unprognostic (8.93e-2)" "unprognostic (6.19e-3)" "unprognostic (1.34e-1)" "unprognostic (1.67e-1)" "unprognostic (3.09e-1)" "prognostic unfavorable (5.26e-4)" "unprognostic (2.50e-2)" "unprognostic (6.50e-3)" "unprognostic (5.76e-2)" "unprognostic (8.86e-2)" "unprognostic (1.04e-1)" "unprognostic (8.57e-3)" "unprognostic (1.60e-1)" "unprognostic (3.47e-1)" "unprognostic (4.50e-2)" "prognostic favorable (7.49e-4)" 13.9 22.5 13.5 13.2 15.6 8.0 20.0 15.9 17.3 17.0 14.9 11.8 9.5 18.9 23.2 11.6 16.4 13.1 22.9 15.7 14.2 17.4 19.7 10.9 22.5 12.4 13.3 20.5 12.9 26.1 12.0 11.5 12.1 19.7 10.8 15.9 19.1 19.9 20.6 12.6 9.7 14.5 13.9 20.8 15.7 14.6 13.3 15.6 24.7 20.8 21.4 14.5 8.1 13.8 10.8 15.4 16.9 14.8 27.1 29.2 8.5 20.8 26.0 18.4 20.2 8.5 4.1 43.8 13.9 15.0 20.5 17.8 24.8 17.5 25.9 35.2 30.7 13.3 12.0 15.0 42.6 24.0 14.7 30.5 34.7 8.7 32.8 26.7 20.6 17.9 21.4 23.2 32.5 10.4 21.9 19.6 19.6 24.1 21.3 18.8 41.2 18.0 24.7 14.8 19.2 20.4 16.2 21.4 25.8 15.0 22.8 13.4 18.1 20.8 11.2 41.7 20.1 36.0 21.9 28.5 20.0 14.8 20.4 12.7 19.2 6.4 23.3 20.0 55.5 35.9 28.2 25.9 26.3 28.9 25.7 25.0 3.5 52.9 15.5 18.9 20.3 23.1 13.5 15.6 15.9 17.3 15.7 14.2 12.4 13.3 12.1 13.9 13.3 13.8 27.3 28.9 33.6 14.4 39.7 12.4 46.6 35.1 8.0 34.0 19.9 30.4 68.1 24.3 23.8 25.8 14.6 19.1 29.2 5.9 76.3 27.3 130.1 25.8 41.0 29.2 14.5 13.2 31.1 22.5 12.7 33.4 12.8 19.0 27.8 33.5 15.4 29.8 25.7 32.0 26.4 11.7 32.6 27.1 29.3 66.3 27.4 28.4 26.6 18.7 45.4 36.1 38.1 27.6 19.9 21.9 8.4 25.2 25.4 46.0 9.4 42.1 27.5 32.4 13.1 33.1 29.8 111.4 37.6 13.8 11.1 11.1 29.6 33.0 12.6 28.4 ARL2 ARFL2 ENSG00000213465 "ADP ribosylation factor like GTPase 2" P36404 11 65014160-65022184 "FDA approved drug targets, Predicted intracellular proteins" "Cell cycle" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 430.8;Late spermatids: 1125.1;Proximal tubular cells: 505.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044610 Supported Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Focal adhesion sites,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "Nucleoli, Golgi apparatus, Focal adhesion sites, Cytosol" "HPA044610: AB_10964207" "unprognostic (9.23e-2)" "unprognostic (3.66e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (4.58e-4)" "unprognostic (1.61e-1)" "unprognostic (5.08e-2)" "unprognostic (1.07e-3)" "unprognostic (2.34e-1)" "unprognostic (9.85e-3)" "unprognostic (6.43e-2)" "unprognostic (6.87e-3)" "prognostic favorable (7.70e-4)" "unprognostic (2.15e-2)" "unprognostic (1.85e-1)" "unprognostic (1.60e-1)" "unprognostic (4.39e-1)" "unprognostic (1.24e-2)" 124.8 93.7 161.5 40.6 190.2 51.3 112.0 172.4 200.2 106.3 132.3 123.1 52.7 121.2 28.2 67.2 94.6 48.0 169.1 157.0 168.7 138.5 22.5 90.4 37.7 171.5 167.9 95.7 75.3 65.3 68.5 56.1 167.2 84.7 32.9 43.5 67.9 66.6 214.2 95.8 73.4 60.9 171.4 63.4 85.2 116.1 167.4 33.5 85.7 158.1 29.0 112.2 93.5 184.4 162.0 257.0 76.5 115.8 207.4 156.5 70.5 82.5 181.7 111.2 109.1 72.8 110.0 62.1 144.5 112.7 168.1 101.4 82.9 140.0 53.1 65.5 130.6 61.9 109.2 111.9 157.8 77.9 54.9 123.7 114.6 92.6 204.4 160.5 150.4 74.0 152.8 110.1 76.4 194.1 63.1 174.5 120.3 77.7 208.6 33.4 81.6 152.9 120.9 70.6 143.3 79.3 66.4 67.6 225.8 74.4 72.3 94.3 109.2 205.9 68.6 164.7 82.1 37.9 57.6 38.5 97.2 112.5 171.3 46.5 78.2 72.5 120.4 80.2 130.9 163.1 110.0 116.9 101.7 149.0 123.5 137.2 10.2 83.3 48.2 140.1 79.0 136.9 161.5 190.2 172.4 200.2 157.0 168.7 171.5 167.9 167.2 171.4 167.4 184.4 179.1 22.4 43.6 0.0 42.7 81.4 94.4 118.4 63.7 70.2 66.8 83.9 103.2 51.5 66.4 82.8 29.2 179.7 40.0 110.0 268.0 142.0 430.8 42.2 59.0 148.0 83.3 69.4 0.0 76.0 193.5 107.0 29.6 50.7 95.7 71.5 137.4 19.7 98.3 69.0 0.0 68.4 83.4 49.7 73.5 1125.1 71.7 49.5 177.9 0.0 100.6 208.4 55.6 0.0 0.0 68.3 115.7 71.1 16.5 79.9 162.4 505.5 47.0 48.9 65.7 74.2 109.7 126.5 79.4 56.3 82.8 107.3 40.0 65.7 98.0 75.9 ATAD5 "C17orf41, ELG1, FLJ12735, FRAG1" ENSG00000176208 "ATPase family AAA domain containing 5" Q96QE3 17 30831966-30895869 "Predicted intracellular proteins" "DNA damage" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 12.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 59.3;Spermatocytes: 73.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 2.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA066823 Approved "Nucleoplasm,Cytokinetic bridge,Centriolar satellite,Cytosol" "Intracellular and membrane" Yes No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Cytokinetic bridge, Centriolar satellite, Cytosol" "HPA066823: " "unprognostic (3.12e-1)" "unprognostic (7.36e-2)" "unprognostic (1.12e-2)" "unprognostic (1.36e-3)" "unprognostic (3.33e-1)" "unprognostic (1.05e-2)" "unprognostic (1.28e-4)" "unprognostic (1.77e-1)" "unprognostic (1.79e-3)" "unprognostic (7.24e-2)" "unprognostic (2.78e-1)" "unprognostic (3.19e-3)" "unprognostic (6.30e-10)" "unprognostic (3.10e-2)" "unprognostic (1.19e-1)" "unprognostic (3.42e-1)" "unprognostic (1.38e-1)" 0.7 0.4 0.3 2.1 0.2 12.3 1.2 2.6 0.5 0.8 0.1 1.2 1.4 1.0 0.4 1.3 0.7 0.5 0.4 0.3 0.2 0.4 0.5 0.8 3.6 0.2 0.1 0.9 0.5 0.3 0.5 1.4 0.3 0.6 1.6 2.5 0.7 0.4 0.4 2.5 1.4 0.6 0.1 1.4 1.1 2.0 0.3 5.3 0.6 0.1 2.9 0.6 0.9 0.6 7.2 6.0 14.0 13.3 0.3 1.4 5.5 6.3 3.2 6.9 9.8 6.6 5.1 19.5 5.9 2.9 4.7 13.0 9.1 4.7 12.4 4.4 7.9 11.7 8.0 4.6 0.2 23.1 9.2 0.6 0.6 10.1 3.5 1.4 3.6 18.7 18.7 15.9 4.6 4.2 26.1 11.5 8.2 5.3 2.9 17.6 26.4 9.3 1.8 7.6 8.1 7.2 7.0 4.0 3.7 7.6 7.6 10.2 2.8 8.3 11.3 12.0 11.4 5.2 5.9 24.0 3.6 10.7 8.4 0.4 0.2 0.3 0.3 0.3 0.2 0.3 0.1 0.2 0.1 0.4 0.2 0.2 0.6 0.6 0.1 0.5 0.3 0.1 0.3 0.2 2.6 0.5 0.3 0.2 0.2 0.1 0.3 0.1 0.3 0.6 4.3 3.2 4.1 6.8 9.9 4.7 3.1 2.6 3.4 19.3 4.7 5.1 2.7 0.0 2.6 3.7 0.0 21.7 10.7 6.6 0.0 4.1 13.9 4.4 8.5 5.4 0.0 59.3 20.4 2.9 21.1 5.4 9.7 5.1 3.8 32.6 2.9 0.7 8.7 11.8 17.4 8.6 2.0 2.8 7.4 7.8 3.7 5.7 7.2 11.2 10.0 2.9 12.3 16.6 14.9 4.0 2.4 2.2 24.4 2.4 2.3 0.5 2.7 21.3 0.0 7.4 6.5 73.3 34.5 9.3 4.5 7.9 10.5 8.4 13.0 2.3 ATP8B1 "ATPIC, BRIC, FIC1, PFIC, PFIC1" ENSG00000081923 "ATPase phospholipid transporting 8B1" O43520 18 57646426-57803315 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hearing, Lipid transport, Transport" Translocase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 76.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 279.7;Intestinal goblet cells: 180.5;Paneth cells: 116.7;Undifferentiated cells: 185.7;Urothelial cells: 119.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 90.2;RT4: 168.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA018673, HPA018674" Enhanced Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 37: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA018673: AB_1845207, HPA018674: AB_1845208" "unprognostic (1.83e-1)" "unprognostic (1.32e-1)" "prognostic favorable (2.60e-4)" "unprognostic (8.81e-2)" "unprognostic (1.32e-3)" "unprognostic (2.06e-1)" "unprognostic (1.39e-1)" "unprognostic (1.02e-1)" "unprognostic (9.62e-3)" "unprognostic (1.97e-1)" "unprognostic (3.30e-3)" "unprognostic (4.55e-3)" "prognostic favorable (6.35e-4)" "unprognostic (1.88e-1)" "unprognostic (2.22e-1)" "unprognostic (3.25e-1)" "unprognostic (8.60e-3)" 9.1 5.4 1.3 8.5 2.0 1.2 9.5 3.6 3.9 16.3 3.0 76.2 30.3 5.9 3.5 14.8 10.6 18.0 4.4 1.7 1.1 6.6 7.7 8.3 2.2 2.1 1.1 2.1 23.3 9.7 2.7 6.9 2.0 17.6 61.7 0.6 20.6 11.5 1.9 8.4 38.2 8.3 1.0 4.6 46.1 0.6 1.9 1.5 22.0 1.8 3.6 30.0 13.0 3.0 32.0 10.7 0.1 0.6 10.5 19.2 11.9 62.6 63.6 67.4 40.4 8.0 24.3 1.5 19.3 90.2 22.3 44.9 0.2 13.9 64.3 0.2 1.1 0.2 2.6 2.5 2.2 0.4 0.6 2.9 12.6 20.8 34.0 39.5 33.0 0.3 0.3 0.7 34.1 15.6 0.1 0.3 0.3 35.5 3.3 0.3 0.2 0.0 7.9 168.1 0.8 0.7 1.3 32.5 0.1 0.5 10.3 0.6 35.3 48.3 2.0 7.7 14.2 0.4 0.4 0.5 1.1 0.4 2.8 0.2 0.2 0.1 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.4 0.1 0.2 0.6 0.0 0.2 0.1 0.0 0.0 1.3 2.0 3.6 3.9 1.7 1.1 2.1 1.1 2.0 1.0 1.9 3.0 25.9 19.2 27.0 11.1 4.1 7.8 66.7 20.6 10.2 0.7 28.4 10.4 5.4 27.1 48.9 40.5 0.0 25.6 0.6 279.7 0.0 27.0 2.8 26.3 4.0 30.8 68.4 0.4 61.2 53.1 2.7 7.1 98.4 40.1 4.5 0.9 33.2 19.1 2.4 6.7 11.7 180.5 22.4 2.8 4.0 0.4 0.3 1.0 7.2 37.5 0.9 0.1 0.0 20.6 10.7 38.5 116.7 0.0 0.9 70.8 58.2 0.2 44.7 1.2 13.1 2.8 20.7 0.3 1.5 28.0 16.3 10.9 1.7 2.3 185.7 119.2 AURKA "AIK, ARK1, AurA, BTAK, PPP1R47, STK15, STK6, STK7" ENSG00000087586 "Aurora kinase A" O14965 20 56369389-56392337 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 22.1;testis: 30.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 81.6;Extravillous trophoblasts: 67.1;granulocytes: 54.1;Spermatocytes: 168.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB001454, HPA002636" Enhanced Approved "Nucleoplasm,Mitotic spindle,Centrosome,Cytosol" Yes Yes "Cluster 7: Monocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Centrosome" "Mitotic spindle, Cytosol" "CAB001454: AB_563420, HPA002636: AB_1845217" "unprognostic (7.73e-2)" "unprognostic (2.46e-2)" "unprognostic (2.76e-2)" "prognostic unfavorable (9.40e-5)" "unprognostic (1.92e-1)" "unprognostic (2.11e-2)" "prognostic unfavorable (1.49e-4)" "unprognostic (4.69e-3)" "unprognostic (2.42e-1)" "unprognostic (6.88e-2)" "prognostic unfavorable (6.13e-4)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.47e-8)" "unprognostic (1.67e-1)" "unprognostic (6.83e-2)" "unprognostic (9.00e-2)" "unprognostic (5.14e-2)" 1.3 2.3 1.3 10.4 1.6 15.3 2.2 2.4 1.4 1.4 0.6 10.8 11.7 1.5 0.8 7.5 1.2 2.0 5.3 0.8 1.0 2.3 5.0 2.2 20.9 1.7 1.2 8.4 2.0 1.8 0.6 8.1 1.4 1.1 12.9 3.0 1.9 1.3 8.7 3.5 9.3 4.9 1.3 5.2 4.9 30.8 1.6 20.2 1.4 8.2 22.1 2.9 2.6 1.3 179.9 127.2 84.5 61.2 4.9 10.8 106.3 145.2 66.8 339.7 142.9 361.4 124.8 58.4 96.2 59.2 176.2 142.2 152.4 96.4 360.0 52.4 57.5 102.6 128.9 229.8 2.8 140.4 140.4 5.1 10.1 117.3 104.5 26.7 80.7 93.2 121.8 45.3 146.9 182.1 85.3 108.9 78.3 145.6 129.8 62.9 163.4 65.9 56.0 46.8 73.9 39.6 200.5 228.8 94.2 77.3 137.9 86.1 47.1 149.7 145.3 83.0 208.6 62.3 78.9 100.5 80.5 80.9 127.0 0.2 3.5 4.3 1.2 5.9 1.8 2.5 2.0 1.1 3.7 0.8 0.9 0.9 2.3 1.4 3.4 0.8 4.7 1.7 1.3 1.6 2.4 1.4 0.8 1.0 1.7 1.2 1.4 1.3 1.6 1.3 2.5 0.0 2.8 0.3 7.4 1.1 1.2 5.6 0.6 1.0 4.3 6.2 5.6 1.5 2.3 3.7 2.1 34.5 8.3 8.3 1.9 4.0 33.9 2.0 2.3 3.1 6.0 81.6 1.1 4.9 67.1 7.0 13.7 3.4 54.1 12.3 3.6 2.6 17.5 1.7 1.5 10.8 2.0 3.5 7.6 16.3 1.5 11.7 0.0 1.0 12.0 3.7 3.1 1.0 2.0 5.2 2.8 0.4 10.1 2.0 5.1 4.2 1.5 2.7 6.6 2.2 7.7 168.2 30.8 8.3 1.1 8.2 8.0 8.7 15.5 1.5 BHLHE22 "Beta3, BHLHB5, CAGL85, TNRC20" ENSG00000180828 "Basic helix-loop-helix family member e22" Q8NFJ8 8 64580365-64583627 "Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 23.2" "Cell type enriched" "Detected in some" 14 "Bipolar cells: 64.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 23 "THP-1: 78.4" "Group enriched" "Detected in all" 5 "amygdala: 30.7;cerebellum: 30.7;cerebral cortex: 22.7;hippocampal formation: 46.3;white matter: 13.1" "HPA064128, HPA064872, HPA067500" Enhanced Approved "Nucleoplasm,Nuclear speckles,Centrosome,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Nuclear speckles" "Centrosome, Cytosol" "HPA064128: AB_2685195, HPA064872: AB_2685377, HPA067500: AB_2685855" "unprognostic (9.17e-2)" "unprognostic (1.11e-2)" "unprognostic (5.44e-2)" "unprognostic (2.28e-5)" "unprognostic (7.22e-3)" "unprognostic (6.47e-4)" "unprognostic (2.41e-1)" "unprognostic (1.08e-1)" "unprognostic (1.30e-1)" "unprognostic (6.58e-2)" "unprognostic (1.52e-1)" "unprognostic (3.71e-2)" "unprognostic (2.86e-7)" "unprognostic (3.20e-2)" "unprognostic (2.29e-1)" "unprognostic (6.72e-3)" "unprognostic (1.86e-1)" 2.0 0.5 8.9 1.4 6.6 0.0 1.5 12.1 22.4 2.3 0.4 1.3 0.4 0.3 0.1 0.9 0.8 0.4 0.3 23.2 1.5 0.2 0.5 2.0 0.7 5.5 1.5 0.2 0.7 0.1 1.4 0.0 2.6 0.4 0.5 4.4 0.5 2.3 0.1 0.8 1.4 0.4 1.4 1.4 0.5 0.2 1.1 0.3 0.7 0.0 0.6 1.2 2.9 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 78.4 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 6.6 12.1 22.4 23.2 1.5 5.5 1.5 2.6 1.4 1.1 1.8 0.3 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 64.7 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 1.2 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 3.1 0.0 3.4 0.2 0.0 0.0 0.6 1.5 0.0 1.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 3.0 0.0 0.2 2.9 0.0 0.4 0.1 1.6 0.0 0.1 0.0 0.0 0.0 BLVRB "FLR, SDR43U1" ENSG00000090013 "Biliverdin reductase B" P30043 19 40447765-40465764 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 625.2" "Cell type enhanced" "Detected in all" "Erythroid cells: 3131.8;Hofbauer cells: 1099.2;Proximal enterocytes: 864.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 465.2" "Group enriched" "Detected in all" 7 "dendritic cells: 343.3;monocytes: 465.2" "Cell line enhanced" "Detected in many" "A549: 506.6;K-562: 506.8;OE19: 451.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041698, HPA041937" Enhanced Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" No No 370000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" Cytosol "Nucleoplasm, Vesicles, Plasma membrane" "HPA041698: AB_10796781, HPA041937: AB_10794308" "unprognostic (1.86e-1)" "unprognostic (1.14e-2)" "unprognostic (4.23e-1)" "unprognostic (1.50e-1)" "unprognostic (2.08e-1)" "unprognostic (2.46e-1)" "unprognostic (9.92e-2)" "unprognostic (1.20e-2)" "unprognostic (8.56e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (3.90e-4)" "unprognostic (2.30e-1)" "unprognostic (2.70e-1)" "unprognostic (2.02e-1)" "unprognostic (5.11e-2)" "unprognostic (1.25e-1)" "unprognostic (3.92e-2)" 115.7 76.8 46.6 48.2 46.9 625.2 93.8 49.4 61.0 86.2 52.1 78.5 75.1 59.0 20.5 188.8 69.3 50.9 125.6 44.5 48.0 103.1 266.2 102.8 58.9 56.0 48.6 66.7 73.2 46.1 25.2 52.1 58.5 74.3 30.3 5.5 89.4 42.2 210.4 83.9 72.2 31.7 49.8 166.7 138.4 10.2 52.3 27.5 64.5 94.1 25.3 81.0 96.5 53.4 227.9 506.6 7.3 77.7 73.7 70.2 57.3 28.0 88.7 39.3 75.4 103.4 203.8 74.3 212.3 56.3 126.8 73.1 30.4 64.6 10.5 123.8 20.0 114.9 73.4 62.4 169.8 1.6 32.2 69.2 119.4 52.4 34.2 40.1 41.8 27.4 506.8 137.0 51.0 359.2 6.1 7.2 1.9 451.4 133.8 54.0 23.4 120.3 50.9 146.5 0.4 10.5 84.5 224.5 84.4 13.2 221.5 17.6 39.2 99.4 103.9 156.4 15.9 71.7 92.1 28.5 259.1 46.2 39.0 45.5 465.2 18.0 29.2 220.9 27.0 58.2 24.3 24.5 343.3 37.5 24.7 19.3 58.4 27.4 117.7 75.8 37.3 259.4 46.6 46.9 49.4 61.0 44.5 48.0 56.0 48.6 58.5 49.8 52.3 53.4 74.6 221.2 164.5 9.4 34.4 129.4 348.5 337.9 103.6 11.2 93.8 143.0 130.5 164.5 184.2 97.5 6.2 84.9 39.5 343.6 266.1 234.2 10.0 56.5 46.3 51.1 44.9 3131.8 5.2 267.3 94.7 112.5 280.3 83.1 43.1 31.0 57.1 680.8 1099.2 10.1 5.1 223.5 158.7 627.7 165.4 23.6 124.2 286.7 144.1 13.1 219.8 88.0 32.0 2.0 5.6 260.4 464.0 94.0 25.7 229.7 864.3 488.3 139.1 13.5 32.9 65.4 146.0 2.6 4.0 160.3 130.4 74.7 34.5 34.7 191.0 260.5 BMI1 "PCGF4, RNF51" ENSG00000168283 "BMI1 proto-oncogene, polycomb ring finger" P35226 10 22321099-22331484 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 134.0;Late spermatids: 165.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 508.3;U-937: 583.9" "CAB011120, HPA030471, HPA030472" Supported Approved "Nucleoplasm,Nucleoli,Nuclear bodies,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 44: HDLM-2 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Nuclear bodies" "Nucleoli, Cytosol" "CAB011120: , HPA030471: AB_2673491, HPA030472: AB_10601090" "unprognostic (5.44e-1)" "unprognostic (2.98e-1)" "unprognostic (4.24e-2)" "unprognostic (4.37e-2)" "unprognostic (2.76e-3)" "unprognostic (6.93e-2)" "prognostic unfavorable (2.60e-8)" "unprognostic (9.43e-2)" "unprognostic (7.95e-2)" "unprognostic (7.84e-2)" "unprognostic (8.23e-2)" "unprognostic (1.56e-1)" "unprognostic (7.44e-2)" "unprognostic (9.73e-2)" "unprognostic (8.56e-2)" "unprognostic (7.91e-3)" "unprognostic (3.41e-2)" 29.0 31.1 26.6 25.1 35.1 21.9 36.0 29.9 42.4 27.6 28.2 26.2 19.7 30.7 29.7 21.9 22.6 23.9 20.5 25.0 27.8 26.0 35.6 23.4 27.7 29.5 30.1 21.7 25.7 56.9 25.0 28.7 31.6 33.7 21.5 40.4 19.9 26.1 44.4 14.4 20.8 36.2 29.9 36.2 22.5 35.3 28.1 24.9 23.9 35.5 27.0 23.8 14.8 45.4 74.9 36.1 41.2 12.7 68.9 54.6 40.5 49.7 22.2 37.3 43.5 37.6 93.4 38.1 32.8 45.6 42.2 26.1 59.1 35.0 45.4 508.3 72.8 104.7 28.7 42.9 41.1 39.8 55.7 35.5 58.8 41.2 45.3 47.0 26.2 62.1 105.4 63.3 48.6 30.2 106.9 11.4 9.3 36.3 83.4 79.6 57.1 37.3 35.3 25.2 33.8 66.0 32.7 42.5 57.3 17.8 38.5 153.8 56.4 41.4 122.6 99.6 67.6 76.1 110.8 83.1 59.5 583.9 27.4 15.1 1.3 2.5 5.2 3.0 7.0 4.4 5.3 5.0 0.9 2.2 4.4 4.3 0.6 5.2 2.1 1.6 4.1 2.0 26.6 35.1 29.9 42.4 25.0 27.8 29.5 30.1 31.6 29.9 28.1 45.4 18.9 25.6 24.0 0.0 23.1 15.9 20.5 12.4 22.8 20.9 24.4 20.3 19.0 22.8 19.8 12.9 8.4 12.7 14.2 5.6 13.7 16.3 134.0 12.1 25.3 24.0 13.2 19.1 0.0 18.2 22.2 19.8 7.7 9.8 12.0 12.6 28.5 30.7 9.9 30.3 0.0 9.9 14.2 19.7 25.6 165.1 36.1 13.8 37.4 0.0 17.5 13.9 15.5 0.0 0.0 22.9 7.3 36.5 33.9 29.1 4.6 13.0 16.9 15.2 19.7 26.5 28.6 19.8 22.2 11.2 14.6 6.7 22.4 17.0 10.3 20.4 BOP1 KIAA0124 ENSG00000261236 "BOP1 ribosomal biogenesis factor" Q14137 8 144262045-144291438 "Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 76.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 223.5" "Low region specificity" "Detected in all" "HPA047869, HPA066764" Approved Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 26: Non-specific - Mitochondria" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "HPA047869: AB_2680193, HPA066764: AB_2685716" "unprognostic (6.92e-2)" "unprognostic (5.03e-3)" "unprognostic (6.78e-2)" "unprognostic (2.06e-3)" "unprognostic (3.32e-1)" "unprognostic (2.16e-2)" "prognostic unfavorable (3.35e-5)" "unprognostic (2.25e-2)" "unprognostic (4.14e-1)" "unprognostic (3.31e-1)" "unprognostic (2.26e-2)" "unprognostic (7.00e-2)" "prognostic unfavorable (2.23e-7)" "unprognostic (7.83e-2)" "unprognostic (4.33e-1)" "unprognostic (8.49e-2)" "unprognostic (4.06e-3)" 18.1 17.8 6.8 8.8 6.9 9.7 16.3 7.7 10.9 16.1 3.5 17.3 5.6 18.2 1.0 26.0 13.2 2.8 24.4 7.6 5.5 16.7 21.5 13.3 8.0 7.1 6.0 11.1 32.0 5.6 16.9 3.7 6.5 15.3 1.9 1.1 13.2 3.1 76.6 21.4 14.9 3.1 4.7 20.4 15.4 20.1 6.2 5.4 17.0 8.1 3.6 19.3 16.5 6.1 45.0 87.4 11.8 50.6 6.4 7.7 41.4 30.5 6.5 30.3 19.1 66.3 25.4 54.1 50.1 11.6 11.5 34.9 21.2 36.2 6.9 47.8 82.5 68.4 54.4 49.7 15.1 30.8 35.6 15.5 17.0 25.2 22.1 5.7 18.8 48.3 70.1 18.1 11.9 112.8 82.4 37.6 28.3 45.1 223.5 61.4 17.6 82.2 12.5 30.1 64.7 25.8 32.5 41.9 20.3 5.5 30.6 27.7 36.6 27.8 83.3 37.1 88.5 16.5 11.7 45.6 20.3 48.6 36.7 0.0 2.2 1.3 1.9 2.3 2.1 2.5 2.2 2.5 3.0 1.8 2.0 1.8 0.1 1.8 2.0 2.0 2.0 1.2 6.8 6.9 7.7 10.9 7.6 5.5 7.1 6.0 6.5 4.7 6.2 6.1 12.8 9.6 5.1 3.9 16.7 0.5 18.7 0.0 13.1 9.8 12.7 13.8 7.2 10.0 3.7 11.0 0.0 25.2 20.9 18.7 5.9 25.8 11.2 7.5 10.7 12.0 26.9 22.1 4.4 21.7 45.3 13.2 17.3 8.3 10.2 13.5 4.6 14.8 21.5 15.2 3.5 11.5 0.0 11.1 0.0 24.3 10.5 12.8 0.0 1.0 16.2 16.7 18.6 5.0 2.8 26.4 11.3 9.8 25.4 39.5 11.3 17.2 1.5 4.6 13.1 12.9 15.1 13.9 53.4 25.7 0.1 17.8 11.8 29.6 31.8 14.3 BYSL Enp1 ENSG00000112578 "Bystin like" Q13895 6 41921499-41933046 "Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031217, HPA031219" Enhanced Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA031217: AB_10599488, HPA031219: AB_10601989" "unprognostic (6.12e-3)" "unprognostic (6.97e-2)" "unprognostic (2.90e-1)" "unprognostic (2.33e-3)" "unprognostic (4.38e-2)" "unprognostic (2.73e-3)" "prognostic unfavorable (6.43e-4)" "unprognostic (2.09e-2)" "unprognostic (2.51e-1)" "unprognostic (6.38e-2)" "unprognostic (1.30e-1)" "unprognostic (2.03e-1)" "prognostic unfavorable (2.15e-8)" "unprognostic (4.39e-2)" "unprognostic (2.18e-1)" "unprognostic (2.79e-3)" "unprognostic (5.99e-2)" 10.7 10.1 6.0 8.2 6.1 7.4 8.8 5.7 6.2 6.4 5.8 6.8 4.7 8.2 5.4 9.2 8.5 5.4 7.2 6.1 6.7 6.5 10.7 5.1 8.4 6.0 6.7 8.1 11.6 6.5 3.6 10.0 6.9 6.8 7.0 2.5 4.8 6.5 20.1 8.0 4.0 11.9 5.9 5.8 5.5 7.9 6.6 12.2 5.2 10.8 13.2 15.4 5.9 6.2 50.6 52.1 30.2 54.2 21.8 25.5 59.7 44.0 21.6 66.7 48.9 72.1 15.7 78.2 43.9 32.9 51.9 34.3 91.6 61.0 58.0 30.1 89.2 72.7 37.3 81.5 38.6 58.8 36.0 30.1 39.5 67.2 62.1 16.9 50.5 47.3 96.1 26.0 48.7 70.8 74.2 68.3 29.0 162.4 50.9 77.9 38.2 57.3 45.2 37.9 65.6 37.4 30.0 37.8 58.2 26.3 38.0 58.6 39.3 49.0 53.5 31.4 77.2 24.6 33.0 185.8 14.5 57.9 49.9 0.0 3.8 0.7 4.3 3.9 5.9 3.8 2.5 3.5 6.0 5.5 1.6 3.3 0.5 6.1 3.0 9.2 3.3 2.3 6.0 6.1 5.7 6.2 6.1 6.7 6.0 6.7 6.9 5.9 6.6 6.2 6.4 0.0 3.9 0.7 6.7 31.0 34.5 19.2 8.6 2.8 8.6 8.5 2.8 5.7 9.5 1.8 4.2 22.1 4.8 4.6 3.9 21.4 10.4 7.9 12.1 10.9 5.4 6.3 2.8 17.5 24.4 11.4 4.6 9.8 2.5 11.4 3.9 6.8 12.0 0.0 2.5 6.5 12.2 1.0 7.3 6.8 8.1 5.1 8.8 1.9 6.6 4.4 9.2 4.0 2.8 23.5 2.9 7.2 4.9 26.2 2.2 10.5 5.1 3.4 6.6 16.1 13.8 10.8 25.7 14.0 25.3 29.1 4.1 18.2 11.4 32.2 C2orf68 ENSG00000168887 "Chromosome 2 open reading frame 68" Q2NKX9 2 85605254-85612066 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051143 Uncertain Approved "Nucleoplasm,Nuclear membrane,Nucleoli,Mitochondria" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nuclear membrane, Mitochondria" Nucleoli "HPA051143: AB_2681360" "unprognostic (1.71e-2)" "unprognostic (3.65e-2)" "unprognostic (1.07e-2)" "prognostic unfavorable (1.12e-6)" "unprognostic (9.34e-2)" "unprognostic (2.16e-1)" "prognostic unfavorable (6.76e-6)" "unprognostic (4.24e-3)" "unprognostic (8.41e-2)" "unprognostic (2.34e-1)" "unprognostic (2.88e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (1.11e-6)" "unprognostic (1.18e-1)" "unprognostic (1.76e-1)" "unprognostic (3.70e-2)" "unprognostic (8.81e-3)" 11.0 9.4 8.8 10.0 11.6 10.5 12.6 15.4 9.9 18.7 10.7 13.6 11.0 15.7 12.2 12.1 15.2 6.6 12.3 8.6 9.4 12.8 11.7 14.0 14.2 11.7 10.8 20.4 17.2 8.5 14.0 12.5 11.0 16.4 10.9 20.0 16.4 10.7 21.8 16.3 16.6 9.9 9.8 16.9 14.3 9.5 10.2 13.7 16.3 9.8 13.9 13.6 15.4 15.2 8.8 7.9 15.7 11.5 14.2 7.6 10.2 4.3 5.6 6.7 8.7 7.1 10.6 12.4 6.0 7.3 6.0 10.4 7.9 7.5 7.2 6.8 19.1 21.1 13.8 8.5 11.2 12.3 11.4 11.3 9.7 4.4 12.7 10.6 10.1 14.7 10.7 12.4 6.3 9.3 13.3 13.4 6.9 10.2 7.3 14.8 27.8 11.5 8.5 10.1 19.8 14.2 6.5 8.5 9.0 8.7 9.1 6.5 7.0 4.8 12.8 5.9 4.2 17.9 11.8 10.8 7.2 12.9 6.0 32.7 30.5 59.0 22.4 21.8 21.3 14.6 21.1 21.0 22.4 20.7 30.5 28.2 49.2 31.2 27.0 15.2 17.7 16.7 8.8 11.6 15.4 9.9 8.6 9.4 11.7 10.8 11.0 9.8 10.2 15.2 8.2 64.1 63.1 15.0 18.6 5.9 18.2 10.0 9.6 17.4 16.0 12.3 10.7 37.1 24.3 35.0 35.5 47.2 24.4 24.6 17.6 17.9 4.8 9.4 8.7 13.9 19.2 19.5 2.7 19.8 17.7 12.9 17.9 9.6 34.7 15.6 17.9 25.3 23.3 25.2 6.8 16.9 12.2 34.9 14.3 12.8 24.2 26.0 14.2 15.0 31.4 12.3 38.1 10.1 16.9 19.4 14.0 13.5 13.6 14.4 32.7 26.6 21.0 27.0 19.7 13.7 8.5 37.2 20.1 27.4 9.8 24.9 18.1 10.0 15.8 19.2 C7orf26 MGC2718 ENSG00000146576 "Chromosome 7 open reading frame 26" Q96N11 7 6590021-6608726 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042899, HPA052175" Uncertain Approved "Nucleoplasm,Nucleoli,Intermediate filaments,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "Nucleoli, Intermediate filaments, Cytosol" "HPA042899: AB_2678218, HPA052175: AB_2681750" "unprognostic (4.85e-2)" "unprognostic (6.87e-2)" "unprognostic (4.51e-2)" "unprognostic (2.50e-2)" "unprognostic (2.18e-2)" "unprognostic (5.22e-2)" "unprognostic (4.28e-3)" "unprognostic (1.49e-1)" "unprognostic (1.18e-1)" "unprognostic (1.34e-1)" "prognostic favorable (6.95e-5)" "unprognostic (4.72e-2)" "unprognostic (2.26e-3)" "unprognostic (4.41e-1)" "unprognostic (1.03e-2)" "unprognostic (3.40e-3)" "unprognostic (1.55e-1)" 18.1 18.9 16.9 12.2 18.2 21.3 18.9 15.9 18.5 23.0 15.0 21.6 12.6 23.3 6.5 16.5 22.2 9.3 17.6 16.3 16.2 19.6 21.5 17.2 17.3 18.8 17.2 19.9 21.7 10.1 17.0 7.2 16.9 22.9 7.1 3.8 16.6 9.8 21.9 21.4 18.6 11.1 16.0 27.2 20.0 17.3 17.3 18.5 19.0 10.2 10.9 20.9 17.1 20.4 21.5 17.6 12.0 28.5 19.3 10.7 15.8 12.6 10.9 17.8 10.9 16.5 8.7 25.2 16.0 9.4 33.7 23.3 16.2 11.5 8.1 9.9 23.3 9.4 11.5 17.6 22.5 22.7 29.0 12.4 17.0 10.7 11.2 9.4 19.6 26.7 25.1 18.6 10.7 36.1 19.9 46.9 24.0 10.6 23.2 40.1 9.5 21.5 11.6 18.5 15.7 29.2 12.2 39.9 17.3 12.5 18.3 33.8 14.2 14.7 48.2 16.3 27.9 22.5 23.8 23.8 9.9 24.9 44.3 0.5 1.5 2.2 2.0 1.5 2.6 1.7 2.4 2.6 1.1 1.6 2.4 2.0 1.4 1.6 1.6 2.9 2.7 0.9 16.9 18.2 15.9 18.5 16.3 16.2 18.8 17.2 16.9 16.0 17.3 20.4 12.9 9.6 8.6 11.1 13.7 15.2 8.8 4.6 13.1 7.1 14.2 14.5 6.0 12.8 6.1 1.8 6.2 11.6 23.6 11.8 0.0 8.9 8.2 9.9 12.6 12.8 12.6 4.2 9.5 10.2 10.6 11.2 10.7 8.9 1.3 16.0 12.5 7.4 13.4 5.0 8.3 12.5 8.2 11.3 10.2 3.5 8.1 12.9 7.2 7.5 8.4 6.7 18.6 9.5 13.2 10.2 9.8 8.6 10.9 10.9 8.5 8.0 5.3 6.5 6.6 12.0 14.5 11.9 13.5 11.7 12.8 9.7 17.5 14.0 11.6 7.6 C9orf153 bA507D14.1 ENSG00000187753 "Chromosome 9 open reading frame 153" Q5TBE3 9 86220265-86259657 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 20.8" "Group enriched" "Detected in some" 26 "Early spermatids: 268.6;Late spermatids: 244.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in single" "HeLa: 1.3" "Not detected" "Not detected" HPA079466 Approved "Nucleoplasm,Nuclear bodies,Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 78: Testis - Spermatogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 34: Spermatids - Unknown function" "Nuclear bodies, Plasma membrane" "Nucleoplasm, Vesicles" "HPA079466: " "unprognostic (2.03e-1)" "unprognostic (1.79e-1)" "unprognostic (1.13e-2)" "unprognostic (2.33e-2)" "unprognostic (1.78e-1)" "unprognostic (5.30e-3)" "unprognostic (7.49e-2)" "unprognostic (2.75e-2)" "unprognostic (3.37e-1)" "unprognostic (6.85e-2)" "unprognostic (9.70e-2)" "unprognostic (1.49e-1)" "unprognostic (2.01e-6)" "unprognostic (9.43e-2)" "unprognostic (1.92e-1)" "unprognostic (9.64e-2)" "unprognostic (2.10e-1)" 0.1 0.4 0.3 0.4 0.2 2.6 0.2 1.4 0.9 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.4 0.1 0.2 0.2 0.1 0.1 0.2 0.5 0.5 0.6 0.2 0.1 0.1 0.0 0.9 0.6 0.1 0.1 0.6 0.2 0.2 0.0 0.3 0.2 0.1 0.0 0.2 0.3 20.8 0.5 0.1 0.2 0.1 0.0 0.0 0.0 1.3 0.2 0.8 0.0 0.4 0.0 0.4 0.3 0.2 0.0 0.0 0.2 0.0 0.6 0.8 0.2 0.2 0.5 0.2 0.0 0.0 0.1 0.1 0.3 0.0 1.3 0.2 0.1 0.2 0.2 0.1 0.6 0.1 0.0 0.0 0.3 0.9 0.0 0.5 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.2 0.2 0.7 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.3 0.6 0.1 0.2 0.4 0.1 0.3 0.0 0.1 0.4 0.8 1.6 0.2 0.3 0.6 0.1 0.1 0.1 0.1 1.2 0.2 0.1 0.1 0.5 0.3 0.2 0.2 0.1 1.5 0.3 0.2 1.4 0.9 0.2 0.2 0.5 0.6 0.6 0.0 0.5 1.3 0.3 0.0 0.0 9.8 0.1 0.0 0.3 0.0 0.0 0.2 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 268.6 0.4 0.5 0.7 0.0 0.0 4.8 0.0 0.1 0.4 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.4 244.8 2.8 0.1 1.8 1.0 0.1 0.4 2.1 6.6 9.7 0.1 0.0 0.7 0.4 0.3 0.0 0.1 0.0 0.1 0.0 1.3 0.7 1.8 1.9 0.0 0.1 0.1 0.2 0.3 0.1 0.2 CAMTA2 KIAA0909 ENSG00000108509 "Calmodulin binding transcription activator 2" O94983 17 4967992-4987675 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Late spermatids: 54.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027835, HPA051147" Supported "Nucleoplasm,Vesicles,Actin filaments,Mitochondria,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "Vesicles, Actin filaments, Mitochondria, Cytosol" "HPA027835: , HPA051147: AB_2681362" "unprognostic (2.82e-1)" "unprognostic (3.06e-1)" "unprognostic (1.11e-2)" "unprognostic (1.01e-3)" "unprognostic (1.10e-1)" "unprognostic (3.24e-2)" "unprognostic (2.36e-1)" "unprognostic (4.71e-2)" "unprognostic (2.78e-2)" "unprognostic (7.08e-2)" "prognostic favorable (6.00e-8)" "unprognostic (3.42e-2)" "unprognostic (9.02e-2)" "unprognostic (3.73e-2)" "unprognostic (1.20e-1)" "unprognostic (4.56e-2)" "unprognostic (1.19e-1)" 15.8 15.6 10.7 13.6 15.9 10.3 15.0 5.2 36.7 14.8 0.0 19.6 10.3 17.0 4.4 14.4 14.4 8.7 17.7 24.2 3.4 16.0 12.9 18.4 9.7 10.0 4.4 14.8 17.5 19.2 26.0 7.4 8.5 15.1 10.8 10.7 13.9 11.6 38.0 17.4 19.0 14.2 0.5 21.6 18.6 14.5 7.3 10.4 17.0 27.5 9.5 16.0 13.0 18.4 13.2 23.2 4.2 6.1 27.8 19.0 8.6 12.4 13.8 11.6 10.1 5.9 3.6 15.5 11.9 19.7 9.8 13.1 16.2 19.5 6.6 21.8 20.7 9.8 13.3 6.6 15.9 5.8 40.4 13.4 24.0 10.8 17.1 14.0 19.6 11.8 16.2 13.9 11.0 8.8 10.3 3.7 0.6 15.6 9.5 8.9 4.8 6.1 13.1 13.8 5.8 5.1 7.8 14.1 3.8 7.2 12.6 5.6 25.6 9.1 5.3 9.8 20.6 6.8 8.0 5.6 22.4 11.5 9.2 0.5 1.2 0.9 1.3 1.6 1.0 0.6 0.6 1.2 0.7 0.4 0.8 1.0 3.0 0.6 4.9 1.1 0.5 1.4 10.7 15.9 5.2 36.7 24.2 3.4 10.0 4.4 8.5 0.5 7.3 18.4 15.2 3.2 11.3 11.4 9.2 6.9 3.7 11.6 8.6 14.7 11.9 8.9 8.0 12.8 6.9 11.0 10.4 5.9 9.0 16.1 1.9 7.9 30.1 5.9 12.6 10.0 11.4 7.4 17.9 11.2 9.6 12.3 20.4 11.6 13.3 14.7 16.8 15.3 8.5 35.3 15.7 13.9 20.3 16.7 10.2 54.3 10.2 13.1 3.6 4.7 14.9 6.5 12.3 9.0 9.5 10.6 13.9 9.4 9.0 6.3 20.1 15.4 6.1 11.2 13.1 7.9 14.8 7.2 6.9 8.8 10.4 12.4 11.4 14.4 12.2 4.1 CAPS2 ENSG00000180881 "Calcyphosine 2" Q9BXY5 12 75275979-75390928 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 11.8" "Cell type enhanced" "Detected in many" "Astrocytes: 85.5;Excitatory neurons: 133.8;Inhibitory neurons: 95.8;Oligodendrocyte precursor cells: 117.1;Oligodendrocytes: 102.6;Respiratory ciliated cells: 77.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 6.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA039542, HPA040004" Uncertain Approved Nucleoplasm,Nucleoli,Vesicles,Centrosome Yes No "Cluster 4: T-regs - Cell cycle regulation" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoli "Nucleoplasm, Vesicles, Centrosome" "HPA039542: , HPA040004: AB_10794758" "unprognostic (1.38e-2)" "unprognostic (1.21e-1)" "unprognostic (7.26e-2)" "unprognostic (5.10e-2)" "unprognostic (3.05e-2)" "unprognostic (1.55e-2)" "unprognostic (2.66e-1)" "unprognostic (2.36e-1)" "unprognostic (9.61e-2)" "unprognostic (1.24e-1)" "unprognostic (2.02e-3)" "unprognostic (1.01e-1)" "unprognostic (1.32e-2)" "unprognostic (3.07e-1)" "unprognostic (1.75e-1)" "unprognostic (4.52e-2)" "unprognostic (2.69e-1)" 1.0 1.5 1.2 0.3 1.2 0.5 1.4 1.7 4.0 1.2 8.8 1.0 0.6 2.0 3.7 1.3 10.0 1.3 2.3 1.1 3.1 2.7 1.8 2.4 0.3 5.5 4.3 1.6 0.9 3.9 2.5 0.1 2.5 2.0 0.6 11.8 2.4 1.3 1.7 0.9 0.6 0.6 2.7 1.0 1.3 3.8 2.3 0.6 4.0 3.2 0.3 0.7 0.7 2.6 0.7 2.1 0.6 0.1 1.0 0.7 0.0 0.4 0.1 1.1 1.2 0.0 1.0 0.2 1.8 0.3 0.4 0.5 0.0 1.0 0.8 0.7 0.3 0.9 0.4 0.0 0.0 0.1 0.0 0.3 0.5 0.9 0.2 6.8 0.1 0.7 0.2 0.3 1.5 0.0 1.0 0.8 0.3 0.0 0.3 0.0 0.0 0.1 1.5 0.0 1.2 0.6 0.1 0.0 0.6 0.1 0.7 0.3 0.5 1.0 0.5 0.2 0.1 0.1 0.0 0.0 0.9 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.3 0.0 1.2 1.2 1.7 4.0 1.1 3.1 5.5 4.3 2.5 2.7 2.3 2.6 3.3 9.6 2.8 85.5 1.7 1.8 2.6 2.9 7.4 1.5 3.1 3.0 8.2 1.5 11.5 5.5 4.2 1.2 0.9 0.4 5.9 1.1 35.8 24.3 2.1 2.3 0.0 4.6 133.8 1.7 0.6 4.8 4.6 0.9 0.0 6.0 3.3 2.4 0.5 1.7 95.8 1.3 2.0 1.6 1.7 14.9 6.2 1.3 0.0 46.9 0.1 6.7 2.1 117.1 102.6 0.6 0.3 7.2 2.5 1.0 0.5 3.5 77.2 22.4 0.0 3.8 3.8 8.5 1.6 4.1 0.6 0.3 1.6 3.3 0.8 0.6 CCDC59 "BR22, HSPC128, TAP26" ENSG00000133773 "Coiled-coil domain containing 59" Q9P031 12 82223681-82358805 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038555 Approved Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Plasma membrane" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Nucleoli rim" "Nucleoplasm, Plasma membrane" "HPA038555: AB_10669543" "unprognostic (1.61e-1)" "unprognostic (6.28e-3)" "unprognostic (1.27e-1)" "unprognostic (2.11e-2)" "unprognostic (1.13e-1)" "unprognostic (6.73e-2)" "unprognostic (1.42e-3)" "unprognostic (1.50e-2)" "unprognostic (1.86e-2)" "unprognostic (1.22e-2)" "unprognostic (2.62e-1)" "unprognostic (5.56e-2)" "prognostic unfavorable (1.39e-6)" "unprognostic (5.73e-2)" "unprognostic (2.01e-1)" "unprognostic (8.86e-2)" "unprognostic (1.02e-2)" 12.9 6.3 7.1 5.2 7.4 40.3 10.9 7.8 10.3 9.2 3.7 10.0 4.2 9.2 10.9 10.6 10.0 7.0 9.0 7.1 6.5 6.5 9.7 8.0 8.8 7.4 6.1 11.3 7.8 9.6 6.7 9.6 7.0 7.0 7.5 4.7 6.7 6.7 16.0 8.5 6.0 8.0 6.1 6.3 7.4 12.3 6.9 12.5 8.6 19.3 11.1 11.1 8.7 10.2 27.2 22.9 18.9 16.0 22.5 20.1 33.1 24.0 28.5 43.4 35.3 52.9 16.0 31.0 12.0 26.0 29.9 18.3 95.3 46.7 36.4 35.7 51.3 34.3 15.1 34.6 66.7 40.3 15.7 36.1 39.0 43.5 55.9 34.6 35.9 55.8 62.8 17.1 26.9 50.6 39.6 57.1 30.4 25.6 54.4 28.4 31.9 27.6 23.4 28.4 33.8 16.4 27.4 15.6 34.6 23.1 32.3 55.0 17.6 18.0 16.3 15.1 45.7 22.7 30.2 66.2 15.7 32.8 29.0 25.9 9.2 18.3 10.7 12.6 22.0 16.4 19.0 20.9 9.9 24.1 22.2 18.7 22.3 14.9 19.0 21.4 29.5 5.9 7.1 7.4 7.8 10.3 7.1 6.5 7.4 6.1 7.0 6.1 6.9 10.2 76.6 67.3 56.3 10.1 81.7 85.8 129.9 84.9 65.4 33.7 57.3 80.1 44.3 40.0 66.5 44.1 22.9 80.0 88.2 33.1 129.1 48.7 125.8 63.1 71.5 62.0 35.8 41.2 9.4 57.5 88.3 61.5 29.6 85.0 78.6 45.8 64.2 53.9 56.8 43.7 9.9 62.5 50.8 70.9 53.8 28.4 53.4 62.0 48.0 5.6 66.9 47.2 64.9 12.1 17.2 54.8 44.0 53.8 54.7 88.1 56.1 93.0 51.5 40.6 19.7 118.1 57.8 204.9 135.2 57.6 89.9 146.8 95.6 43.5 56.7 100.6 CCDC85C ENSG00000205476 "Coiled-coil domain containing 85C" A6NKD9 14 99500190-99604207 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 72.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 62.6;Rod photoreceptor cells: 51.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058346, HPA061922" Uncertain Approved "Nucleoplasm,Nucleoli rim,Nuclear bodies,Mitotic chromosome,Cell Junctions" Yes No "Cluster 20: T-cells - T-cell receptor" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 44: HDLM-2 - Immune response" "Cluster 44: Endometrium - Transcription" "Nucleoli rim, Cell Junctions" "Nucleoplasm, Nuclear bodies, Mitotic chromosome" "HPA058346: AB_2683686, HPA061922: " "unprognostic (7.17e-2)" "unprognostic (2.23e-2)" "unprognostic (3.64e-1)" "prognostic unfavorable (1.44e-4)" "unprognostic (5.70e-2)" "unprognostic (2.61e-1)" "unprognostic (1.68e-3)" "unprognostic (4.80e-2)" "unprognostic (1.45e-2)" "unprognostic (8.75e-2)" "unprognostic (3.30e-1)" "unprognostic (1.68e-3)" "prognostic favorable (2.60e-5)" "unprognostic (4.14e-2)" "unprognostic (1.95e-1)" "unprognostic (8.74e-3)" "unprognostic (9.81e-3)" 5.2 22.0 26.4 4.3 32.9 9.7 7.1 72.9 27.1 5.8 20.6 31.3 18.7 15.4 14.3 28.3 11.3 5.4 19.6 24.8 20.9 14.4 18.2 8.1 2.5 30.8 24.1 5.1 18.5 16.4 17.0 8.6 27.0 15.0 11.1 34.7 26.4 16.2 20.7 19.4 17.7 13.1 24.5 3.6 19.2 8.5 28.6 5.0 9.3 5.6 7.5 16.1 8.9 21.0 48.4 43.4 52.7 31.7 0.7 0.2 48.9 16.0 16.2 31.4 18.1 52.9 49.8 0.3 61.7 18.2 8.6 63.3 39.2 38.4 19.5 79.2 23.3 2.5 43.6 36.1 4.2 0.5 4.9 0.1 19.9 9.0 25.9 18.6 9.9 27.9 11.8 7.2 3.9 80.3 21.8 6.6 19.3 55.4 44.7 32.1 22.1 10.8 22.3 18.8 26.0 32.6 40.7 21.5 9.5 19.9 46.9 9.8 22.6 6.2 51.5 22.4 16.2 11.2 15.8 0.4 1.0 4.3 4.5 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.2 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.4 0.1 26.4 32.9 72.9 27.1 24.8 20.9 30.8 24.1 27.0 24.5 28.6 21.0 8.5 22.4 5.6 15.7 6.7 8.8 8.7 4.0 13.6 35.2 12.1 9.3 3.0 5.7 7.3 1.8 62.6 6.3 3.9 21.2 0.0 7.6 3.1 18.8 8.1 9.2 9.6 3.4 2.8 9.4 4.5 6.2 17.3 35.6 6.3 14.1 5.3 16.7 1.8 1.7 5.4 9.6 6.1 1.6 1.2 2.1 0.6 5.0 8.8 4.7 0.4 30.6 1.0 1.5 11.7 17.4 13.2 0.7 10.4 11.0 23.3 6.5 3.0 51.7 0.0 5.7 4.1 1.4 3.5 20.4 14.1 4.9 8.3 2.3 13.0 12.0 CCDC86 MGC2574 ENSG00000110104 "Coiled-coil domain containing 86" Q9H6F5 11 60842113-60851081 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "parathyroid gland: 377.6" "Cell type enhanced" "Detected in many" "Spermatocytes: 74.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041117, HPA041540" Enhanced Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 28: Myeloid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 25: RPMI-8226 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoli, Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA041117: AB_10794984, HPA041540: AB_10794299" "unprognostic (2.93e-1)" "unprognostic (6.59e-2)" "unprognostic (2.38e-1)" "unprognostic (1.47e-3)" "unprognostic (3.64e-1)" "prognostic unfavorable (7.36e-5)" "prognostic unfavorable (1.71e-4)" "unprognostic (1.65e-3)" "unprognostic (9.52e-2)" "unprognostic (1.25e-2)" "unprognostic (6.12e-2)" "unprognostic (4.47e-1)" "unprognostic (3.76e-2)" "unprognostic (7.54e-3)" "unprognostic (2.90e-1)" "unprognostic (2.16e-1)" "unprognostic (6.25e-2)" 25.6 26.7 12.0 14.3 13.3 10.2 20.8 13.1 14.2 12.9 11.2 14.1 11.4 16.7 3.5 19.4 15.2 6.9 16.0 12.7 13.5 19.2 13.7 11.8 11.6 13.2 13.5 13.8 23.9 377.6 24.9 11.6 13.7 23.9 5.8 8.2 12.2 8.6 34.7 22.7 12.3 10.4 12.3 12.7 16.4 48.9 12.7 8.8 12.9 13.7 8.5 20.2 14.5 14.1 83.4 110.2 26.5 76.1 21.8 35.7 36.3 54.3 42.4 98.1 52.4 95.0 53.7 98.9 100.7 31.0 69.7 73.3 94.2 65.7 48.2 35.7 101.3 51.0 45.8 133.2 70.7 80.7 82.6 39.5 48.7 90.2 61.8 14.3 75.8 53.5 166.0 46.9 50.3 97.3 125.2 122.6 107.0 48.6 156.3 81.4 39.6 253.5 37.2 33.8 59.9 38.9 34.7 79.5 64.6 17.6 80.8 30.3 45.9 93.6 59.6 131.6 118.2 41.0 66.5 109.2 78.2 86.0 118.6 1.7 13.5 4.2 9.1 29.4 9.7 9.4 9.6 8.3 29.8 9.0 11.5 10.2 1.0 6.9 9.3 16.6 9.7 10.1 12.0 13.3 13.1 14.2 12.7 13.5 13.2 13.5 13.7 12.3 12.7 14.1 9.3 0.0 2.2 2.0 8.9 37.0 22.2 5.7 28.5 12.1 9.9 10.3 0.6 4.3 4.0 1.8 8.4 17.2 5.7 5.3 7.9 18.6 25.6 6.8 9.4 12.7 7.2 8.8 2.0 12.2 20.4 10.2 9.7 7.7 5.1 7.9 3.6 3.1 18.4 3.3 1.7 5.7 6.1 2.5 16.5 15.0 11.5 7.3 16.0 1.0 5.3 3.9 4.1 1.0 1.3 19.2 3.6 6.0 8.6 24.0 4.4 7.3 1.3 8.3 19.7 10.7 19.1 74.6 18.8 21.2 31.0 8.2 7.0 12.5 11.3 18.8 CD180 "LY64, Ly78, RP105" ENSG00000134061 "CD180 molecule" Q99467 5 67179613-67196799 "CD markers, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 23.3" "Cell type enhanced" "Detected in some" "B-cells: 53.6;Hofbauer cells: 78.6;Kupffer cells: 23.5;Macrophages: 17.5;monocytes: 13.8;Plasma cells: 39.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "memory B-cell: 77.0;naive B-cell: 78.9" "Group enriched" "Detected in many" 25 "B-cells: 78.9;dendritic cells: 23.5;monocytes: 34.5" "Group enriched" "Detected in some" 10 "Daudi: 45.2;Karpas-707: 41.1;U-266/70: 33.1;U-266/84: 49.0;U-698: 12.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA003740 Enhanced Approved "Nucleoplasm,Nucleoli,Plasma membrane,Mitotic spindle" Yes NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "Nucleoplasm, Nucleoli, Mitotic spindle" "HPA003740: AB_1078450" "unprognostic (9.33e-2)" "unprognostic (4.58e-2)" "unprognostic (2.81e-3)" "unprognostic (5.85e-3)" "unprognostic (2.25e-2)" "unprognostic (4.04e-3)" "unprognostic (1.09e-1)" "unprognostic (4.95e-2)" "unprognostic (5.83e-2)" "unprognostic (3.71e-1)" "unprognostic (2.16e-1)" "unprognostic (1.46e-1)" "unprognostic (2.09e-1)" "unprognostic (1.16e-1)" "unprognostic (3.70e-2)" "unprognostic (1.21e-1)" "unprognostic (2.18e-2)" 1.6 0.7 0.7 9.7 0.7 2.4 6.7 0.6 1.2 0.5 0.4 2.1 2.0 0.5 0.2 0.4 0.4 1.6 0.4 0.8 0.7 0.3 2.5 1.6 23.2 1.5 1.5 0.2 0.3 0.2 0.1 3.2 2.0 0.5 2.7 0.3 1.1 0.4 0.1 0.2 3.9 1.8 1.0 12.9 2.2 0.4 1.8 2.5 0.3 0.2 23.3 3.0 0.1 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 45.2 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 41.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.1 0.6 0.2 33.1 49.0 12.3 0.0 2.7 0.0 0.3 11.8 0.9 0.0 20.4 0.0 77.0 0.1 0.1 22.1 78.9 0.0 0.0 0.9 1.8 34.5 23.5 0.1 8.5 0.7 0.7 0.6 1.2 0.8 0.7 1.5 1.5 2.0 1.0 1.8 2.1 0.1 0.0 0.5 0.3 53.6 0.4 0.1 0.0 0.0 0.1 1.8 1.1 0.7 1.5 0.0 0.0 0.0 0.4 4.0 0.0 0.0 0.0 2.2 0.1 0.0 0.6 0.0 1.7 0.0 0.2 0.3 0.4 0.0 0.1 2.5 0.0 0.0 0.3 78.6 0.0 0.0 0.0 0.0 23.5 8.0 1.0 0.0 17.5 0.0 1.9 13.8 0.1 0.0 0.0 0.0 0.3 0.0 0.0 39.6 0.0 0.0 0.1 0.7 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.7 2.2 0.0 0.1 0.1 CDC6 CDC18L ENSG00000094804 "Cell division cycle 6" Q99741 17 40287879-40304657 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA replication, Mitosis" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.2;lymphoid tissue: 17.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 23.2;Erythroid cells: 37.2;Extravillous trophoblasts: 34.6;Plasma cells: 31.6;Spermatocytes: 69.5;Spermatogonia: 57.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 3.6" "Group enriched" "Detected in many" 6 "dendritic cells: 3.6;NK-cells: 1.5;T-cells: 2.4" "Cell line enhanced" "Detected in all" "SK-BR-3: 500.3" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA050114, HPA065070" Approved Approved "Nucleoplasm,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "Cytokinetic bridge, Mitotic spindle" "HPA050114: AB_2681021, HPA065070: AB_2732729" "unprognostic (1.29e-1)" "unprognostic (7.22e-2)" "unprognostic (1.23e-3)" "unprognostic (7.97e-2)" "unprognostic (7.12e-2)" "unprognostic (2.89e-2)" "prognostic unfavorable (5.96e-8)" "unprognostic (2.31e-3)" "unprognostic (1.46e-3)" "unprognostic (1.41e-1)" "prognostic unfavorable (2.90e-4)" "unprognostic (5.47e-2)" "unprognostic (3.00e-15)" "unprognostic (1.86e-2)" "unprognostic (1.35e-1)" "unprognostic (3.95e-3)" "unprognostic (3.88e-2)" 2.1 1.9 0.5 13.7 0.8 27.2 3.4 0.2 1.9 3.2 0.0 8.4 7.5 2.2 1.1 5.7 1.0 2.8 0.6 1.1 0.1 0.5 3.0 1.4 16.4 0.1 0.0 0.9 1.9 0.8 0.5 9.3 0.3 1.1 8.7 0.5 1.3 1.2 0.3 2.8 6.7 3.7 0.0 3.7 3.6 10.1 0.2 16.7 1.7 0.5 17.1 4.3 1.8 0.6 155.1 119.0 115.1 86.5 6.7 12.7 118.0 159.9 49.0 149.2 166.5 135.8 64.9 123.9 99.6 35.9 85.9 214.0 112.2 76.2 148.9 64.5 98.4 96.2 122.3 134.6 4.4 133.3 55.1 4.7 8.1 156.4 107.1 14.8 46.9 84.2 183.0 109.0 71.9 95.8 199.3 43.3 101.6 96.9 48.7 145.0 286.8 119.9 30.3 184.8 85.6 76.9 146.9 500.3 55.4 100.3 100.8 120.0 34.7 95.5 146.3 170.8 196.1 46.1 103.6 222.8 84.6 93.9 109.2 0.1 0.1 0.0 0.8 0.0 0.5 0.4 0.6 1.1 0.7 0.3 0.4 1.1 0.1 1.5 0.0 3.6 2.4 0.6 0.5 0.8 0.2 1.9 1.1 0.1 0.1 0.0 0.3 0.0 0.2 0.6 2.2 0.0 2.0 0.7 4.9 4.2 1.1 3.7 3.4 0.2 2.1 2.2 0.9 1.5 1.3 0.0 0.0 23.2 2.3 7.8 0.0 1.3 2.2 1.3 2.9 2.1 0.0 37.2 2.0 0.6 34.6 5.6 3.6 5.1 0.0 8.1 1.1 0.9 8.3 0.0 0.7 6.1 0.0 1.3 2.1 1.0 2.8 1.5 0.0 0.0 0.0 0.4 2.1 0.0 0.2 1.5 3.0 0.7 31.6 1.3 0.8 0.2 0.2 0.3 13.1 0.6 4.6 69.5 57.2 9.1 1.6 16.7 3.3 1.9 9.3 2.4 CDK4 PSK-J3 ENSG00000135446 "Cyclin dependent kinase 4" P11802 12 57747727-57756013 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in all" 5 "glioma: 175.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 10 "HBEC3-KT: 2594.8;LHCN-M2: 2819.4;RH-30: 8902.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006024, CAB013116, CAB069405" Supported Supported "Nucleoplasm,Nuclear membrane,Nucleoli,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 89: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "Nucleoplasm, Nuclear membrane, Nucleoli" "CAB013116: AB_2536376, CAB069405: AB_1613464, HPA006024: AB_2667497" "unprognostic (8.88e-2)" "unprognostic (2.53e-1)" "unprognostic (5.27e-2)" "unprognostic (9.01e-2)" "unprognostic (2.21e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (2.09e-7)" "unprognostic (7.39e-2)" "unprognostic (3.23e-3)" "unprognostic (2.93e-2)" "unprognostic (3.19e-2)" "unprognostic (9.10e-2)" "prognostic unfavorable (3.15e-5)" "unprognostic (3.32e-1)" "unprognostic (1.67e-1)" "unprognostic (3.64e-1)" "unprognostic (1.57e-2)" 69.7 87.8 35.0 52.8 37.9 72.0 76.6 37.7 36.9 84.3 35.9 62.6 40.2 97.4 64.2 57.2 69.4 57.1 58.9 33.6 37.1 58.5 51.5 58.0 66.8 37.1 36.9 97.3 70.9 63.5 67.7 52.4 36.8 52.7 63.3 14.5 54.4 54.1 48.2 58.9 47.2 80.4 37.3 51.5 54.8 24.1 37.3 67.6 66.0 52.7 70.6 71.6 60.7 37.6 207.1 235.7 295.7 268.0 253.7 220.7 210.4 116.1 347.9 468.5 385.7 338.2 189.1 297.4 200.2 173.6 293.2 158.0 396.3 2594.8 354.9 150.9 209.0 275.4 149.5 237.9 297.0 309.7 182.5 221.5 180.9 294.2 326.7 326.4 304.8 280.0 301.3 242.7 2819.4 304.9 296.7 256.5 347.0 208.0 249.8 267.3 8902.5 272.1 147.2 320.6 271.2 251.7 205.3 150.2 310.0 195.1 202.8 380.7 146.1 233.6 217.0 265.8 233.1 122.2 206.1 450.8 214.1 291.3 286.9 9.5 46.5 10.3 79.6 65.6 81.8 93.5 70.0 72.5 66.7 90.0 93.0 84.4 4.4 56.6 41.9 84.9 57.0 73.6 35.0 37.9 37.7 36.9 33.6 37.1 37.1 36.9 36.8 37.3 37.3 37.6 47.1 22.4 30.8 7.8 40.0 89.7 78.6 83.4 74.0 15.9 67.2 82.2 0.7 51.5 35.3 47.8 10.4 82.9 26.1 15.9 70.5 93.1 13.5 14.9 77.7 50.8 45.6 98.0 5.2 62.5 134.5 79.4 28.5 22.6 69.1 60.2 39.7 35.8 132.9 18.5 6.7 42.2 40.7 25.1 44.1 8.0 64.0 31.2 53.4 6.5 41.9 51.4 29.9 5.5 8.0 48.3 18.9 63.2 57.8 113.9 14.0 80.9 7.4 17.9 32.9 62.1 61.9 32.1 48.3 74.5 86.1 46.8 32.3 78.8 78.7 49.4 CDK7 "CAK, CAK1, CDKN7, MO15, STK1" ENSG00000134058 "Cyclin dependent kinase 7" P50613 5 69234795-69277430 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 121.0;Extravillous trophoblasts: 343.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 169.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004364, HPA007932, HPA008453, CAB079975" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Nucleoli fibrillar center, Plasma membrane, Cytosol" "CAB004364: AB_627243, CAB079975: , HPA007932: AB_1078492, HPA008453: " "unprognostic (3.12e-2)" "unprognostic (1.23e-1)" "unprognostic (4.87e-2)" "unprognostic (4.53e-2)" "unprognostic (3.29e-2)" "unprognostic (4.64e-2)" "unprognostic (2.49e-3)" "unprognostic (1.64e-2)" "unprognostic (7.77e-3)" "unprognostic (1.81e-2)" "prognostic unfavorable (3.09e-4)" "unprognostic (3.40e-2)" "prognostic unfavorable (9.42e-7)" "unprognostic (2.61e-1)" "unprognostic (2.38e-1)" "unprognostic (3.86e-2)" "unprognostic (1.55e-2)" 13.4 19.8 9.4 9.5 10.2 29.1 14.8 10.9 12.9 17.5 11.5 13.7 13.3 12.1 12.9 37.3 12.5 6.4 12.4 9.5 10.5 18.4 13.6 12.7 4.8 9.7 9.7 11.7 14.1 3.2 18.2 16.2 9.8 13.7 7.4 12.8 18.9 4.8 26.8 25.3 12.2 7.7 9.8 12.6 13.5 30.6 10.0 9.3 13.2 15.0 13.3 16.1 19.9 9.4 42.8 5.9 19.4 30.6 6.4 24.4 169.5 30.9 37.5 46.2 42.9 62.2 64.5 3.7 36.4 36.8 34.2 65.3 10.8 31.3 40.6 9.0 3.1 8.6 21.4 25.9 32.8 17.9 33.8 7.1 61.3 1.8 46.0 24.5 32.5 22.3 16.3 16.1 13.3 33.3 9.4 51.7 20.7 2.8 25.4 12.3 0.7 27.1 42.6 25.4 8.6 17.5 11.6 50.4 42.4 28.1 44.9 39.3 7.4 17.1 27.4 33.1 18.2 14.4 30.4 16.5 31.4 10.2 15.5 27.9 7.9 16.2 5.3 8.9 7.9 10.6 7.8 10.6 7.3 14.5 5.9 6.4 8.2 8.6 4.7 8.9 10.5 6.1 9.4 10.2 10.9 12.9 9.5 10.5 9.7 9.7 9.8 9.8 10.0 9.4 12.2 16.0 13.2 10.7 7.8 57.7 21.4 32.9 15.4 6.4 12.3 14.7 11.3 10.0 20.2 5.5 12.5 121.0 11.7 10.2 15.6 27.8 26.8 33.1 10.7 11.6 3.0 9.9 17.6 21.6 343.6 13.0 9.7 27.2 15.8 7.4 7.1 6.7 24.0 1.7 13.7 12.3 20.3 8.5 6.0 7.9 7.5 8.5 7.2 11.2 11.6 10.4 15.5 8.0 11.9 29.3 16.2 7.2 5.8 28.2 12.3 29.3 42.4 8.7 26.3 10.0 12.5 70.1 18.6 15.9 41.9 64.6 11.4 6.8 13.2 29.8 CENPC "CENP-C, CENPC1, hcp-4, MIF2" ENSG00000145241 "Centromere protein C" Q03188 4 67468762-67545503 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049740, HPA058252" Supported "Nucleoplasm,Nuclear bodies,Kinetochore,Midbody" Yes Yes "Cluster 21: B-cells - Adaptive immune response" "Cluster 21: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Nuclear bodies, Kinetochore" "Nucleoplasm, Midbody" "HPA049740: , HPA058252: AB_2683654" "unprognostic (4.35e-1)" "unprognostic (6.41e-3)" "unprognostic (4.31e-3)" "unprognostic (7.85e-2)" "unprognostic (6.31e-2)" "unprognostic (3.85e-3)" "unprognostic (6.40e-2)" "prognostic favorable (9.67e-4)" "unprognostic (3.22e-2)" "unprognostic (7.13e-2)" "unprognostic (8.35e-2)" "unprognostic (4.32e-2)" "prognostic favorable (5.63e-4)" "unprognostic (2.40e-1)" "unprognostic (1.92e-1)" "unprognostic (1.15e-1)" "unprognostic (1.92e-3)" 1.5 1.6 2.5 1.0 3.2 3.6 3.3 5.6 2.6 2.8 0.2 2.0 1.1 3.1 2.3 1.5 2.9 1.1 1.5 2.2 2.0 2.0 1.4 1.5 1.8 1.3 1.8 5.6 3.8 1.5 2.5 1.3 1.7 2.9 1.2 2.7 2.0 1.6 1.1 2.3 1.8 1.5 1.3 2.0 2.1 1.7 1.7 2.0 3.1 1.1 1.5 2.0 2.3 2.8 0.4 0.5 1.6 0.9 1.9 1.1 0.9 0.6 0.5 0.7 0.5 0.7 1.3 2.7 0.8 0.8 0.2 0.8 2.2 0.9 1.2 0.8 0.4 2.1 0.9 0.9 0.6 3.9 0.8 1.4 0.3 0.5 1.3 1.2 0.4 1.8 3.0 1.6 1.1 0.7 5.3 3.5 1.8 0.8 0.3 2.4 4.0 0.9 1.0 0.8 2.8 1.3 1.2 2.5 0.7 1.6 0.7 1.3 0.4 1.0 0.5 0.7 0.5 1.3 0.5 2.7 1.1 2.2 0.6 0.5 0.2 0.5 0.7 0.4 0.3 0.8 0.8 0.9 0.2 1.1 1.2 0.9 0.2 0.5 0.2 0.4 0.4 0.2 2.5 3.2 5.6 2.6 2.2 2.0 1.3 1.8 1.7 1.3 1.7 2.8 53.1 32.1 35.5 38.8 68.4 15.2 25.3 17.7 35.9 53.7 26.0 32.3 24.3 18.6 31.6 16.5 14.6 20.2 75.0 17.7 11.7 13.5 4.1 21.0 39.0 33.7 13.1 31.7 58.5 16.7 12.9 41.3 35.7 25.1 26.6 39.8 23.2 14.1 12.8 52.2 57.0 18.4 18.3 16.7 7.9 5.5 34.8 26.7 16.0 31.9 27.4 31.6 60.8 46.3 74.6 14.6 13.0 25.6 89.1 15.3 24.2 20.4 27.2 29.0 19.7 54.1 34.2 47.2 44.4 34.7 9.2 18.3 69.8 43.3 16.4 23.9 CEP112 "CCDC46, MGC33887" ENSG00000154240 "Centrosomal protein 112" Q8N8E3 17 65635537-66192133 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 49.0" "Group enriched" "Detected in many" 8 "Early spermatids: 1061.4;Late spermatids: 1606.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "LHCN-M2: 32.0;RH-30: 75.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069724 Approved "Nucleoplasm,Midbody ring,Centrosome,Cytosol" Yes NA "Cluster 11: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Centrosome" "Midbody ring, Cytosol" "HPA069724: " "unprognostic (9.35e-2)" "unprognostic (3.08e-2)" "unprognostic (2.93e-1)" "unprognostic (6.21e-2)" "unprognostic (1.06e-2)" "unprognostic (4.11e-3)" "unprognostic (1.43e-2)" "unprognostic (7.99e-2)" "unprognostic (4.48e-3)" "unprognostic (3.37e-2)" "unprognostic (1.39e-3)" "unprognostic (3.50e-2)" "unprognostic (4.46e-3)" "unprognostic (1.02e-2)" "unprognostic (1.26e-1)" "unprognostic (3.52e-2)" "unprognostic (2.71e-1)" 11.3 3.9 5.0 2.7 5.4 1.7 9.5 7.1 5.8 8.3 11.9 7.8 2.0 8.5 8.2 4.3 8.3 7.0 8.0 7.4 5.1 5.6 3.2 7.4 2.5 5.8 5.7 8.2 4.6 8.7 8.3 7.2 4.2 7.2 3.1 25.4 3.0 7.9 8.8 3.3 2.9 8.0 3.4 8.8 4.2 49.0 5.5 2.8 7.1 14.0 1.7 5.4 5.9 3.4 5.0 10.5 13.3 3.8 6.9 14.0 0.4 4.5 7.7 5.5 5.0 1.5 2.0 1.6 4.3 9.8 15.5 0.6 2.9 2.9 7.8 2.6 4.8 0.3 4.7 1.9 2.9 0.6 0.2 8.4 4.8 5.2 1.6 11.0 16.8 2.7 0.3 5.0 32.0 0.7 5.3 0.4 1.3 1.1 4.4 1.5 75.9 0.4 6.0 0.3 3.5 7.4 4.7 0.5 3.6 11.4 3.8 0.4 7.9 14.3 8.2 3.9 6.7 2.3 2.1 0.2 4.4 0.2 5.3 1.3 0.4 0.4 0.3 0.2 0.6 0.3 0.8 0.3 0.2 0.8 0.5 0.3 1.3 0.8 0.2 1.4 0.5 0.1 5.0 5.4 7.1 5.8 7.4 5.1 5.8 5.7 4.2 3.4 5.5 3.4 39.7 9.6 35.8 83.6 1.1 2.5 2.9 2.2 2.2 36.7 2.7 5.5 28.3 4.3 15.3 1.8 20.9 0.7 0.8 1.5 1.9 7.4 1061.4 15.3 15.8 25.4 1.8 0.4 117.4 4.7 1.5 12.4 1.5 3.3 2.5 11.2 19.2 0.2 1.8 1.7 103.8 0.3 0.0 0.8 11.3 1606.0 24.8 2.3 14.2 99.3 0.0 14.7 1.0 29.7 6.6 4.4 0.5 19.9 0.4 1.5 0.0 4.3 23.7 154.3 13.1 43.7 12.5 40.6 16.5 2.4 1.6 0.1 2.5 3.1 1.5 1.3 CFAP36 "BARTL1, CCDC104, MGC15407" ENSG00000163001 "Cilia and flagella associated protein 36" Q96G28 2 55519604-55545079 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 1342.4;Late spermatids: 262.5;Spermatocytes: 346.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008994, HPA017061" Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Nuclear bodies,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Nucleoli fibrillar center, Nuclear bodies" Cytosol "HPA008994: AB_2275429, HPA017061: AB_1846129" "unprognostic (8.11e-2)" "unprognostic (3.21e-3)" "unprognostic (1.24e-1)" "unprognostic (3.36e-2)" "unprognostic (7.98e-2)" "unprognostic (3.68e-1)" "unprognostic (4.65e-3)" "unprognostic (7.79e-2)" "unprognostic (1.51e-2)" "unprognostic (1.58e-2)" "unprognostic (3.66e-3)" "unprognostic (7.63e-2)" "unprognostic (8.57e-3)" "unprognostic (4.94e-2)" "unprognostic (3.35e-2)" "unprognostic (1.56e-3)" "unprognostic (2.96e-1)" 39.1 42.7 72.7 20.2 74.8 16.5 48.9 61.8 98.8 49.8 82.8 52.3 15.1 47.1 77.0 21.9 62.3 40.9 35.7 75.0 78.5 63.2 17.7 33.9 21.7 71.8 70.4 58.9 33.6 78.0 106.7 20.6 72.1 41.6 23.2 124.3 28.7 45.0 19.2 18.8 25.2 37.4 65.9 18.2 42.1 145.2 73.6 22.8 78.0 27.1 19.7 40.7 33.6 70.1 59.5 47.3 50.2 66.3 64.4 119.4 30.4 36.6 73.4 54.9 46.6 34.6 21.2 21.3 82.3 48.9 81.9 38.4 39.3 51.4 67.7 51.9 76.2 31.0 43.9 38.1 70.0 59.4 38.4 58.1 82.7 74.0 92.1 146.8 58.9 42.5 40.1 18.2 66.1 44.4 35.7 67.5 25.2 38.7 44.8 27.2 59.7 21.7 112.1 33.7 74.1 36.6 49.4 25.6 68.5 26.2 42.1 19.7 32.5 57.6 33.7 58.5 50.8 29.9 14.2 7.3 94.0 26.7 26.8 15.5 4.3 13.6 18.3 5.0 35.4 16.9 50.6 29.6 5.8 11.7 41.1 26.0 5.2 12.3 6.4 13.5 30.5 15.9 72.7 74.8 61.8 98.8 75.0 78.5 71.8 70.4 72.1 65.9 73.6 70.1 51.3 48.1 30.6 15.7 14.5 0.0 52.6 0.0 22.2 39.6 48.7 77.2 37.9 38.6 27.2 35.0 8.4 14.3 14.8 6.4 92.0 61.9 1342.4 184.4 51.8 42.9 17.0 21.0 51.6 60.7 27.0 44.7 21.9 36.3 39.1 27.1 42.1 10.7 23.6 23.5 41.1 12.2 0.0 8.7 0.0 262.5 75.2 12.8 0.0 14.0 16.9 145.0 16.5 21.6 13.3 37.0 11.5 67.7 11.4 41.3 7.6 146.9 99.1 92.4 59.2 43.0 43.4 346.0 29.8 16.1 0.0 7.8 24.7 36.0 9.9 35.6 CFLAR "c-FLIP, CASH, CASP8AP1, Casper, cFLIP, CLARP, FLAME, FLIP, I-FLICE, MRIT" ENSG00000003402 "CASP8 and FADD like apoptosis regulator" O15519 2 201116154-201176687 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 609.9;Urothelial cells: 521.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "neutrophil: 392.6" "Lineage enriched" "Detected in all" 6 "granulocytes: 392.6" "Cell line enhanced" "Detected in all" "U-266/70: 214.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019044, CAB022157, CAB025216" Uncertain Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA Yes "Cluster 50: Neutrophils - Cellular senescence" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Plasma membrane, Cytosol" "Nuclear bodies" "CAB022157: , CAB025216: , HPA019044: AB_10696204" "unprognostic (4.61e-2)" "unprognostic (5.32e-2)" "unprognostic (2.49e-1)" "unprognostic (1.44e-1)" "unprognostic (2.95e-2)" "prognostic favorable (2.79e-4)" "unprognostic (7.46e-2)" "unprognostic (9.01e-2)" "unprognostic (1.76e-1)" "unprognostic (6.12e-2)" "unprognostic (3.08e-2)" "unprognostic (4.91e-2)" "unprognostic (2.90e-2)" "unprognostic (7.83e-2)" "unprognostic (9.13e-2)" "unprognostic (6.84e-2)" "unprognostic (2.24e-2)" 122.4 50.6 38.8 103.9 40.9 247.6 83.1 54.1 47.4 57.0 75.6 86.0 59.2 57.9 60.6 68.0 66.6 71.6 184.8 39.4 32.7 57.5 59.2 174.6 91.1 46.5 40.5 38.3 40.7 31.8 29.4 94.0 42.1 65.6 56.4 12.4 58.0 63.2 222.8 51.0 64.8 58.8 36.6 98.1 56.5 25.3 51.9 54.1 78.8 89.2 107.3 78.7 61.7 46.1 21.5 42.9 30.0 17.9 92.3 71.0 37.5 53.6 92.1 34.3 41.6 50.4 78.4 5.8 49.6 62.5 41.6 15.5 9.8 40.3 53.9 160.7 29.9 32.3 38.4 82.2 63.6 24.2 102.2 76.8 39.6 58.2 50.3 41.7 176.7 7.3 110.8 131.2 63.1 17.9 11.3 96.3 10.2 17.2 32.7 11.7 7.2 46.5 42.5 44.0 6.6 11.8 35.7 31.2 43.2 19.6 22.1 44.8 193.6 71.0 29.5 26.7 26.1 214.6 76.2 35.9 50.6 19.5 36.3 91.8 60.3 70.3 54.4 61.8 48.4 25.6 46.5 52.1 33.4 20.9 29.5 38.3 392.6 45.2 68.5 23.0 60.7 42.0 38.8 40.9 54.1 47.4 39.4 32.7 46.5 40.5 42.1 36.6 51.9 46.1 191.3 451.9 234.9 30.3 126.4 54.8 229.6 164.9 29.0 10.9 38.9 30.0 205.8 102.9 206.7 69.9 31.3 77.2 166.2 132.5 74.3 148.8 83.3 202.8 75.0 261.0 95.1 59.1 6.9 72.5 34.8 89.5 73.4 219.2 81.6 93.4 201.0 97.5 68.6 13.5 16.8 76.8 40.7 123.2 609.9 44.8 51.9 278.0 97.8 146.1 247.0 23.4 276.0 29.7 56.8 166.4 155.6 49.7 317.8 386.0 116.7 101.5 276.1 30.7 39.5 113.2 77.9 14.4 12.2 33.2 86.1 70.1 168.3 56.1 50.9 521.3 CKS1B "CKS1, ckshs1" ENSG00000173207 "CDC28 protein kinase regulatory subunit 1B" P61024 1 154974653-154979251 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 651.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA003424, HPA030762" Approved Approved Nucleoplasm,Vesicles,Mitochondria,Cytosol NA Yes "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Mitochondria, Cytosol" "Nucleoplasm, Vesicles" "HPA003424: AB_2666948, HPA030762: AB_10670044" "unprognostic (1.06e-2)" "unprognostic (1.62e-1)" "unprognostic (2.84e-1)" "prognostic unfavorable (7.89e-4)" "unprognostic (1.34e-1)" "unprognostic (2.59e-2)" "prognostic unfavorable (2.94e-5)" "unprognostic (2.01e-3)" "prognostic unfavorable (3.12e-5)" "unprognostic (3.63e-2)" "prognostic unfavorable (6.13e-4)" "unprognostic (3.19e-1)" "prognostic unfavorable (6.03e-7)" "unprognostic (3.12e-2)" "unprognostic (1.44e-1)" "prognostic favorable (4.87e-4)" "unprognostic (1.37e-1)" 59.0 31.9 15.0 33.6 15.8 117.7 67.8 16.4 19.8 44.3 15.0 49.4 40.8 35.0 36.8 61.6 40.9 22.2 35.5 15.4 16.2 37.9 73.3 29.0 71.3 17.5 15.8 31.7 22.4 35.5 18.4 50.6 17.7 26.1 50.5 6.0 28.4 32.9 14.5 51.2 44.3 34.8 17.4 37.0 35.5 48.6 15.7 88.7 30.1 23.5 74.1 30.1 42.6 18.8 459.2 616.5 455.9 245.3 66.9 68.1 361.4 209.1 166.8 463.4 367.8 599.9 653.4 433.8 345.9 143.2 251.2 410.6 468.0 305.2 428.7 392.9 293.9 294.6 249.9 426.5 19.4 359.7 257.9 39.8 132.2 391.4 532.8 91.5 232.5 298.2 486.6 566.8 353.9 452.8 337.3 273.9 575.3 442.1 547.6 334.8 373.6 554.3 165.6 164.2 184.3 463.9 313.6 292.0 347.3 530.2 391.6 492.9 126.0 282.5 292.4 237.0 505.3 348.9 734.7 617.0 179.6 300.1 399.8 2.2 13.0 6.9 19.8 82.0 24.4 74.2 28.0 27.1 22.1 70.4 34.0 32.8 1.7 28.7 105.4 92.6 33.3 28.1 15.0 15.8 16.4 19.8 15.4 16.2 17.5 15.8 17.7 17.4 15.7 18.8 31.7 12.8 33.3 1.3 46.5 217.6 101.3 170.6 74.0 3.4 90.6 140.5 9.2 87.2 63.1 29.5 0.0 224.0 40.7 48.3 80.3 93.0 15.8 43.1 24.6 51.9 20.4 140.1 0.8 112.1 651.8 84.6 20.9 28.3 21.0 66.7 29.6 89.8 132.1 1.7 0.8 57.4 120.1 46.0 121.0 21.7 76.1 37.4 113.8 0.0 41.3 20.7 20.6 0.5 3.5 119.0 41.7 45.9 38.4 130.2 63.1 87.5 52.1 3.0 19.7 50.6 53.0 124.7 151.0 74.9 203.6 131.9 40.7 27.2 80.0 99.5 CKS2 ENSG00000123975 "CDC28 protein kinase regulatory subunit 2" P33552 9 89311195-89316703 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 177.3;testis: 186.3" "Cell type enhanced" "Detected in many" "Langerhans cells: 474.6;Spermatocytes: 692.7;Spermatogonia: 503.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 187.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003424, HPA030762" Approved Approved Nucleoplasm,Vesicles,Mitochondria,Cytosol NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "Mitochondria, Cytosol" "Nucleoplasm, Vesicles" "HPA003424: AB_2666948, HPA030762: AB_10670044" "unprognostic (8.30e-2)" "unprognostic (3.00e-1)" "unprognostic (1.50e-2)" "unprognostic (2.80e-2)" "unprognostic (2.96e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (2.51e-6)" "unprognostic (3.57e-3)" "unprognostic (7.04e-2)" "unprognostic (1.34e-2)" "prognostic unfavorable (6.85e-4)" "unprognostic (1.24e-2)" "prognostic unfavorable (1.78e-5)" "unprognostic (2.13e-3)" "unprognostic (1.44e-1)" "unprognostic (2.84e-1)" "unprognostic (1.84e-1)" 13.6 82.9 9.6 38.5 10.0 177.3 20.1 11.9 26.9 10.1 11.8 44.1 43.3 13.0 8.8 53.2 12.1 18.7 10.3 12.7 10.3 35.6 31.2 24.0 102.8 10.5 10.1 9.4 4.2 19.8 4.8 44.3 11.0 15.0 41.0 27.9 10.8 17.8 9.4 19.9 33.1 17.6 10.6 32.6 20.4 186.3 10.8 121.1 12.8 4.8 84.7 26.5 19.9 11.3 685.9 570.1 342.6 230.6 98.7 89.1 249.5 396.1 211.4 428.1 340.0 236.1 328.6 504.9 228.4 149.1 761.4 466.5 415.5 305.1 488.2 398.1 335.5 257.5 378.9 637.5 42.4 531.7 281.2 33.0 69.2 307.2 269.1 162.9 403.2 409.1 313.2 430.6 556.0 509.1 420.7 928.3 501.6 795.5 521.5 358.4 376.4 303.7 342.8 153.5 288.4 171.7 328.7 314.9 324.5 318.4 379.7 304.2 231.4 184.1 350.3 449.6 588.2 345.9 759.2 415.3 271.3 303.1 268.5 40.8 19.5 44.1 22.6 26.5 25.3 61.3 30.4 21.9 22.5 44.7 16.3 21.8 14.5 40.9 14.8 187.9 62.7 23.6 9.6 10.0 11.9 26.9 12.7 10.3 10.5 10.1 11.0 10.6 10.8 11.3 138.6 38.5 103.9 0.3 175.7 280.2 92.1 126.1 259.0 4.1 107.2 169.0 61.3 5.7 49.9 14.7 0.0 231.1 201.1 79.4 23.5 20.1 37.3 149.7 66.4 66.1 122.3 266.9 1.2 11.2 379.4 63.1 74.9 250.2 145.0 144.7 29.3 25.0 184.6 0.0 1.9 164.9 111.9 40.5 474.6 77.0 25.7 164.3 140.5 1.9 31.0 26.1 28.8 1.0 1.1 31.1 67.1 16.6 89.3 72.1 37.6 209.7 32.8 7.3 46.0 75.2 206.5 692.7 503.6 197.5 299.1 199.5 156.0 70.3 162.7 102.1 CMSS1 "C3orf26, MGC4308" ENSG00000184220 "Cms1 ribosomal small subunit homolog" Q9BQ75 3 99817837-100181732 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 215.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042820 Uncertain Approved "Nucleoplasm,Nuclear membrane,Nucleoli,Mitochondria" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoli "Nucleoplasm, Nuclear membrane, Mitochondria" "HPA042820: AB_10795763" "unprognostic (1.50e-1)" "unprognostic (8.28e-2)" "unprognostic (4.61e-2)" "prognostic unfavorable (3.15e-6)" "unprognostic (2.13e-2)" "unprognostic (2.39e-3)" "prognostic unfavorable (5.92e-10)" "unprognostic (1.50e-1)" "unprognostic (5.92e-2)" "unprognostic (5.83e-2)" "unprognostic (6.71e-2)" "prognostic unfavorable (3.10e-4)" "unprognostic (2.18e-3)" "unprognostic (1.56e-1)" "unprognostic (2.26e-1)" "unprognostic (3.25e-1)" "unprognostic (4.04e-2)" 24.5 33.1 23.0 15.8 21.7 20.8 23.4 26.7 30.1 22.4 17.8 21.0 8.6 21.8 9.7 15.8 20.9 10.5 28.2 21.8 20.9 20.7 15.0 15.8 17.1 22.8 20.1 23.6 26.7 21.8 24.5 11.6 19.6 16.0 11.6 24.6 14.0 13.3 69.4 17.4 12.6 13.2 17.9 13.8 16.4 30.3 21.3 16.7 14.8 29.9 15.0 24.5 18.1 21.7 116.2 51.0 50.0 72.6 34.7 40.1 51.0 53.5 28.8 93.3 77.0 64.1 37.5 126.3 90.6 28.2 82.4 68.4 70.3 60.2 120.3 66.8 66.5 99.9 32.9 53.2 62.6 137.0 51.3 28.2 56.7 71.4 116.6 30.3 65.2 100.9 63.5 78.1 67.0 78.8 110.3 126.4 73.0 109.4 126.1 49.1 81.3 134.1 57.2 27.5 139.9 58.9 52.8 42.5 125.0 47.8 51.4 84.0 18.5 73.6 207.4 43.3 109.8 56.3 121.1 244.9 49.1 149.4 124.8 1.0 11.0 2.3 22.2 27.3 32.0 57.3 32.8 30.3 23.8 55.7 41.3 42.0 4.1 28.6 25.1 62.1 33.9 18.2 23.0 21.7 26.7 30.1 21.8 20.9 22.8 20.1 19.6 17.9 21.3 21.7 26.7 6.4 19.4 48.6 41.3 62.2 37.4 45.5 26.2 32.8 43.8 40.4 41.7 42.9 23.2 62.5 18.8 41.7 25.1 8.5 97.8 42.1 165.0 21.7 56.8 38.7 15.0 30.9 154.3 47.7 56.6 44.3 9.7 19.8 62.1 47.7 24.7 61.4 27.2 127.9 132.8 14.4 16.2 7.9 45.5 215.8 50.7 18.7 37.4 58.1 12.8 28.0 19.6 114.1 116.2 35.8 4.6 58.6 36.2 82.8 1.1 87.9 22.4 27.0 26.3 67.3 50.1 163.4 146.1 21.3 66.1 21.9 30.1 54.1 22.6 27.0 COG3 SEC34 ENSG00000136152 "Component of oligomeric golgi complex 3" Q96JB2 13 45464898-45536701 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040353, HPA054470" Approved Supported "Nucleoplasm,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus, Plasma membrane" "Nucleoplasm, Cytosol" "HPA040353: AB_10794027, HPA054470: AB_2732585" "unprognostic (1.75e-1)" "unprognostic (3.03e-3)" "unprognostic (1.75e-1)" "unprognostic (4.04e-3)" "unprognostic (9.69e-2)" "unprognostic (2.86e-2)" "unprognostic (2.18e-2)" "unprognostic (4.46e-2)" "unprognostic (2.51e-2)" "prognostic unfavorable (9.53e-4)" "unprognostic (5.82e-2)" "unprognostic (1.21e-2)" "unprognostic (4.49e-2)" "unprognostic (7.06e-3)" "unprognostic (1.13e-1)" "unprognostic (8.25e-2)" "unprognostic (1.71e-1)" 11.2 15.0 7.5 9.3 7.7 11.8 15.6 10.5 9.3 15.2 10.5 16.2 12.6 13.0 16.8 12.4 12.2 9.5 11.8 7.4 7.2 12.3 29.5 10.4 10.7 7.0 7.0 15.1 20.8 12.3 14.9 13.0 7.0 18.7 18.9 10.0 18.0 12.4 11.4 13.2 13.2 12.1 6.8 12.4 14.7 9.7 7.5 12.2 17.0 9.7 10.9 12.7 13.1 9.4 8.3 7.4 13.9 12.6 17.9 20.4 13.2 13.5 19.1 15.4 12.8 10.8 14.9 11.3 5.9 16.2 11.4 17.7 11.6 13.7 23.3 8.9 9.3 12.7 9.2 19.2 22.1 18.8 11.7 15.4 20.3 10.3 36.1 18.6 15.2 11.0 8.3 6.8 18.7 12.9 10.5 17.6 11.4 41.5 8.7 12.1 8.1 10.6 14.4 13.4 6.9 12.5 8.7 17.1 18.2 13.1 11.7 19.3 14.4 7.4 5.7 13.9 8.7 9.4 5.4 11.7 14.2 9.4 13.5 3.5 1.9 3.6 3.4 2.2 3.6 2.2 2.6 2.9 1.4 2.3 2.9 2.7 1.7 2.5 1.3 3.4 3.0 1.7 7.5 7.7 10.5 9.3 7.4 7.2 7.0 7.0 7.0 6.8 7.5 9.4 15.8 9.6 31.4 23.2 18.9 15.8 15.2 13.1 14.2 9.7 22.0 17.9 19.7 24.3 19.8 12.9 14.6 14.2 35.5 32.5 15.6 11.6 24.1 15.0 20.1 16.7 22.2 11.4 39.3 37.9 18.8 14.3 26.0 30.8 17.1 22.4 18.9 72.8 10.8 10.1 34.7 54.5 6.1 20.9 9.0 9.0 14.0 13.3 10.6 22.5 13.2 7.6 15.5 34.2 36.9 22.7 32.8 13.5 31.3 26.6 29.4 17.3 11.7 11.2 6.6 12.8 11.7 12.7 8.9 17.7 16.1 32.8 21.2 21.7 24.4 37.3 COMMD3-BMI1 ENSG00000269897 "COMMD3-BMI1 readthrough" 10 22316388-22329542 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 10.1;testis: 6.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 23.3;MOLT-4: 12.7;U-937: 23.8" "HPA030471, HPA030472, HPA036584" Uncertain Approved "Nucleoplasm,Nucleoli,Nuclear bodies,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 77: Retina - Visual perception" "Cluster 44: HDLM-2 - Immune response" "Nuclear bodies" "Nucleoplasm, Nucleoli, Cytosol" "HPA030471: AB_2673491, HPA030472: AB_10601090, HPA036584: AB_10670803" "unprognostic (8.63e-2)" "unprognostic (2.36e-2)" "unprognostic (1.83e-2)" 0.9 2.2 0.4 1.0 1.4 0.3 0.8 1.0 1.9 1.5 0.8 0.8 0.6 0.4 0.0 1.8 1.3 0.2 3.0 0.3 1.6 0.4 0.5 0.9 1.0 1.3 0.7 0.6 0.8 0.4 0.1 0.7 0.9 0.5 0.2 10.1 1.8 2.7 6.4 0.7 0.8 0.3 0.4 0.9 1.1 6.7 1.3 2.0 0.4 2.3 1.5 1.0 0.8 2.0 2.1 6.4 3.9 0.2 2.5 2.3 0.4 0.9 1.3 1.4 5.8 7.8 1.2 1.9 0.8 3.0 5.1 1.1 2.8 2.2 1.3 23.3 2.4 5.4 1.5 0.0 1.7 0.6 3.0 2.9 3.2 3.3 0.1 4.3 1.6 8.3 1.4 2.8 0.8 0.0 12.7 0.9 0.4 3.9 2.1 1.7 3.1 1.7 0.5 1.9 0.4 2.7 5.5 1.1 0.2 1.4 0.0 4.7 6.8 2.3 3.9 1.3 0.7 4.9 0.9 3.5 1.2 23.8 0.0 7.4 2.1 3.0 3.4 2.4 3.7 7.5 3.2 4.1 2.2 7.3 2.4 1.8 0.7 4.9 1.3 0.3 6.5 4.9 0.4 1.4 1.0 1.9 0.3 1.6 1.3 0.7 0.9 0.4 1.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CPEB3 KIAA0940 ENSG00000107864 "Cytoplasmic polyadenylation element binding protein 3" Q8NE35 10 92046692-92291078 "Predicted intracellular proteins" "Translation regulation" "Activator, Repressor, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 32.2" "Cell type enhanced" "Detected in many" "Astrocytes: 176.0;Early spermatids: 226.2;Excitatory neurons: 233.7;Inhibitory neurons: 286.9;Late spermatids: 408.9;Oligodendrocyte precursor cells: 148.8;Oligodendrocytes: 128.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Karpas-707: 12.1;U-266/70: 6.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070942 Approved "Nucleoplasm,Plasma membrane,Midbody,Cytosol" Yes No "Cluster 10: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Nucleoplasm, Plasma membrane, Midbody" "HPA070942: " "unprognostic (4.90e-2)" "unprognostic (2.12e-2)" "unprognostic (3.00e-1)" "unprognostic (5.66e-2)" "unprognostic (1.92e-1)" "unprognostic (2.95e-5)" "prognostic favorable (5.06e-5)" "unprognostic (4.09e-4)" "unprognostic (2.73e-1)" "unprognostic (2.40e-1)" "unprognostic (1.47e-2)" "unprognostic (2.42e-2)" "prognostic favorable (3.84e-9)" "unprognostic (3.33e-2)" "unprognostic (7.42e-2)" "unprognostic (1.36e-2)" "unprognostic (1.40e-1)" 1.9 3.9 6.1 1.8 7.2 1.7 3.2 6.2 17.3 2.5 2.1 2.3 3.1 1.9 4.5 4.6 1.8 2.0 5.1 6.4 4.3 4.6 32.2 2.2 1.9 10.4 5.6 3.5 3.5 3.2 4.0 1.6 11.0 4.2 2.6 7.1 7.5 2.4 19.7 4.0 3.0 2.0 1.4 2.6 2.8 12.9 4.4 1.5 6.5 9.5 2.1 1.9 3.1 7.0 0.9 0.2 0.3 1.9 0.5 0.5 0.7 0.8 0.6 1.2 0.9 0.6 1.9 1.1 1.0 0.3 0.5 2.5 0.9 0.6 0.7 1.1 0.9 1.4 1.3 0.8 1.4 0.6 1.4 0.4 1.5 0.6 2.4 1.0 1.1 1.3 0.9 12.1 0.5 0.7 0.9 0.8 0.2 1.3 0.9 1.1 1.6 2.1 1.2 0.4 1.4 0.5 0.8 2.2 1.6 1.0 2.7 1.6 0.8 0.6 0.6 0.4 0.7 6.3 1.7 1.1 0.3 2.2 0.1 2.6 0.4 0.8 0.2 0.5 0.2 0.7 0.1 0.3 0.3 0.1 0.1 0.1 0.5 0.2 0.6 0.2 0.1 0.2 6.1 7.2 6.2 17.3 6.4 4.3 10.4 5.6 11.0 1.4 4.4 7.0 6.1 6.4 7.0 176.0 6.2 8.8 4.0 4.0 7.4 26.0 20.5 10.7 25.3 5.7 4.4 12.9 50.1 2.1 3.0 11.3 5.9 3.2 226.2 9.0 3.0 7.1 19.8 3.6 233.7 2.6 1.6 5.5 4.1 10.8 3.8 4.1 12.5 75.2 4.8 30.3 286.9 9.9 8.2 23.9 3.4 408.9 5.9 10.3 5.4 87.1 8.9 3.2 4.1 148.8 128.6 3.2 4.0 7.9 4.2 10.7 10.1 5.0 8.7 24.7 0.0 4.4 4.1 13.2 7.2 22.0 13.9 1.2 3.3 3.4 5.9 6.5 CRTC1 "FLJ14027, KIAA0616, MECT1, TORC1" ENSG00000105662 "CREB regulated transcription coactivator 1" Q6UUV9 19 18683678-18782333 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Biological rhythms, Host-virus interaction, Transcription, Transcription regulation" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 37.4;Horizontal cells: 43.7" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 203 "amygdala: 14.2;basal ganglia: 11.4;cerebellum: 27.1;cerebral cortex: 24.3;hippocampal formation: 24.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022035, HPA063619" Enhanced Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Nuclear bodies" "Plasma membrane, Cytosol" "HPA022035: AB_1847255, HPA063619: " "unprognostic (5.95e-3)" "unprognostic (2.57e-1)" "unprognostic (9.94e-2)" "unprognostic (8.62e-3)" "unprognostic (9.07e-2)" "unprognostic (1.57e-2)" "unprognostic (1.04e-1)" "unprognostic (5.57e-2)" "unprognostic (2.27e-1)" "unprognostic (6.68e-2)" "prognostic favorable (1.80e-5)" "unprognostic (3.37e-2)" "prognostic favorable (3.83e-5)" "unprognostic (6.83e-3)" "unprognostic (1.02e-1)" "unprognostic (2.51e-2)" "unprognostic (2.03e-2)" 8.8 11.3 14.2 5.2 11.4 2.1 8.2 27.1 24.3 11.3 0.0 8.9 4.0 9.3 3.4 5.2 10.3 3.2 10.5 24.5 0.0 12.8 10.4 7.9 4.1 0.0 0.0 9.4 9.8 4.7 23.7 3.9 0.0 11.6 1.5 4.4 7.3 5.1 14.4 7.4 8.5 2.5 0.0 9.6 9.9 11.3 0.0 3.6 14.4 3.6 2.2 9.7 7.4 0.0 5.2 7.9 6.7 10.7 6.3 4.5 18.6 5.4 3.6 5.3 4.8 5.1 6.6 7.1 11.6 5.2 3.9 5.5 2.1 3.5 1.3 3.1 15.1 6.0 7.8 9.3 5.5 8.3 16.3 7.8 2.9 4.4 1.3 6.8 3.1 7.2 4.8 6.3 3.0 15.2 5.7 10.0 8.8 2.7 13.1 8.7 2.9 8.1 3.2 8.0 12.1 10.7 6.0 5.8 7.0 2.2 6.6 5.2 5.4 6.0 9.1 10.8 6.4 4.4 3.6 4.6 6.9 8.6 4.6 0.3 0.6 0.4 0.4 0.2 0.3 0.5 0.5 0.6 0.7 0.7 0.5 0.3 0.2 0.3 0.4 0.8 0.4 0.4 14.2 11.4 27.1 24.3 24.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 5.3 31.0 6.9 2.7 8.9 7.8 5.7 29.1 5.8 6.1 17.7 10.0 3.5 18.4 27.1 9.7 7.9 6.8 11.7 4.6 1.1 9.6 14.0 5.6 19.2 3.6 37.4 6.0 2.7 7.5 8.6 9.8 2.5 14.7 3.9 4.7 8.8 43.7 26.7 7.1 12.2 6.0 4.0 3.2 9.3 6.3 3.6 10.3 5.5 9.1 8.2 12.1 20.2 3.5 9.6 4.9 2.0 3.0 6.1 5.0 4.8 14.7 0.0 14.2 6.6 2.9 8.8 2.4 2.0 10.4 5.1 8.3 5.2 3.6 CRYL1 "GDH, lambda-CRY, MGC149525, MGC149526" ENSG00000165475 "Crystallin lambda 1" Q9Y2S2 13 20403666-20525873 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 329.8;liver: 254.1" "Cell type enhanced" "Detected in all" "Distal tubular cells: 485.2;Hepatocytes: 306.1;Proximal enterocytes: 509.9;Proximal tubular cells: 1033.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 68.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040403, HPA058848" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Plasma membrane" NA NA 690000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Nucleoli" "Golgi apparatus, Plasma membrane" "HPA040403: AB_10795632, HPA058848: " "unprognostic (1.84e-1)" "unprognostic (1.25e-1)" "unprognostic (3.25e-2)" "prognostic favorable (1.76e-5)" "unprognostic (3.10e-1)" "unprognostic (1.03e-1)" "unprognostic (1.09e-3)" "unprognostic (4.75e-3)" "unprognostic (1.19e-1)" "unprognostic (4.09e-2)" "unprognostic (2.12e-2)" "unprognostic (8.80e-2)" "prognostic favorable (2.30e-9)" "unprognostic (9.00e-2)" "unprognostic (1.30e-1)" "unprognostic (2.39e-2)" "unprognostic (3.11e-1)" 33.7 31.8 69.5 15.4 81.3 11.2 27.1 75.4 78.1 33.0 65.6 62.1 190.2 30.5 51.7 24.7 26.5 30.0 30.4 65.2 79.0 329.8 254.1 19.9 19.4 76.3 71.9 19.8 46.9 31.4 38.1 16.1 76.1 32.2 49.3 20.7 41.6 36.5 17.0 16.3 131.6 22.8 77.2 23.3 45.2 4.9 71.9 18.0 35.0 20.7 16.3 20.9 23.6 89.8 8.1 6.9 6.4 42.7 31.6 36.1 5.8 11.1 20.0 4.8 3.9 2.6 7.8 0.1 20.6 15.5 10.9 1.9 5.7 9.9 4.9 19.4 4.7 14.2 0.8 55.1 18.1 4.6 12.2 21.5 6.4 3.9 22.0 17.1 51.7 20.3 1.0 5.8 12.7 29.2 12.7 7.2 0.4 68.7 10.2 6.4 3.8 1.0 40.8 16.9 4.2 5.0 6.6 3.1 51.0 3.0 21.2 18.0 50.1 5.8 2.6 14.3 7.1 7.6 1.6 0.0 11.1 7.9 24.5 5.8 50.7 3.2 23.2 59.6 18.9 20.5 30.6 22.1 60.5 23.1 23.5 22.2 1.7 15.6 50.6 6.4 37.5 43.8 69.5 81.3 75.4 78.1 65.2 79.0 76.3 71.9 76.1 77.2 71.9 89.8 29.2 6.4 10.3 57.8 17.7 10.3 15.9 29.7 6.2 6.1 22.0 11.6 10.5 35.8 25.6 77.3 12.5 22.0 10.0 138.5 485.2 26.1 3.6 32.5 8.8 29.1 9.1 6.9 54.5 31.6 11.2 29.8 34.1 27.2 25.3 8.8 50.7 306.1 71.4 1.7 35.3 89.0 32.6 91.6 34.3 4.3 26.1 51.3 37.4 13.1 19.3 112.2 9.2 33.7 114.1 43.2 219.1 24.0 14.3 23.0 509.9 1033.9 20.9 12.6 19.7 23.4 14.7 1.0 2.7 13.0 9.2 20.8 20.1 20.7 105.2 15.0 CTNNBIP1 "ICAT, MGC15093" ENSG00000178585 "Catenin beta interacting protein 1" Q9NSA3 1 9848276-9910336 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 177.7;skin 1: 434.9" "Cell type enhanced" "Detected in many" "Muller glia cells: 185.7;Suprabasal keratinocytes: 291.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 13.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067089 Enhanced Approved Nucleoplasm,Nucleoli,Vesicles,Cytosol NA NA 35000 "Cluster 52: Eosinophils - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Cytosol" "Nucleoli, Vesicles" "HPA067089: " "unprognostic (2.71e-1)" "unprognostic (4.46e-2)" "unprognostic (1.94e-1)" "prognostic favorable (5.68e-6)" "unprognostic (3.08e-1)" "unprognostic (2.63e-2)" "unprognostic (2.22e-2)" "unprognostic (1.19e-1)" "unprognostic (2.23e-2)" "unprognostic (2.62e-1)" "unprognostic (2.17e-2)" "unprognostic (1.77e-1)" "unprognostic (1.24e-3)" "unprognostic (3.62e-2)" "unprognostic (3.22e-2)" "unprognostic (8.63e-2)" "unprognostic (4.37e-2)" 34.4 11.1 29.7 11.2 28.2 22.4 35.2 37.3 31.2 59.2 13.1 15.0 18.8 11.8 77.4 177.7 12.5 10.3 43.8 29.5 30.0 17.6 15.7 26.4 8.7 33.8 29.0 14.6 35.9 10.9 19.7 28.2 36.4 24.5 10.2 27.5 53.1 14.1 39.0 434.9 14.9 10.9 27.1 9.3 22.8 27.0 37.5 19.6 21.0 22.3 25.1 13.3 85.1 27.3 74.8 10.9 65.9 50.4 9.8 16.2 21.1 14.4 25.2 20.9 13.3 5.4 92.6 22.9 41.0 18.7 21.6 37.3 7.7 85.9 9.6 58.0 11.9 14.9 3.4 69.3 20.3 11.3 8.4 18.2 83.5 26.7 27.0 17.7 57.2 42.4 26.8 10.5 13.0 45.6 25.3 41.6 35.0 60.0 18.7 28.4 19.3 14.7 10.7 25.2 72.1 45.4 32.9 29.4 44.4 22.3 36.3 27.2 37.7 13.4 16.4 20.4 32.2 22.9 32.5 27.0 5.0 56.6 54.5 2.6 5.2 13.8 2.6 1.8 1.6 1.7 1.3 2.1 6.4 1.5 1.3 1.2 3.7 8.6 1.2 2.0 1.3 2.6 29.7 28.2 37.3 31.2 29.5 30.0 33.8 29.0 36.4 27.1 37.5 27.3 150.6 28.9 13.9 30.0 9.6 103.1 42.3 16.1 40.5 9.0 39.9 33.3 14.0 24.3 17.0 18.4 8.4 71.3 23.5 20.5 33.2 20.9 116.3 20.0 17.9 42.7 49.1 20.0 18.0 18.7 43.2 15.7 30.1 38.5 0.0 27.2 20.0 25.6 58.0 16.8 14.1 37.5 12.2 43.0 97.4 34.8 14.9 38.3 48.0 12.2 33.6 185.7 71.1 17.1 24.1 37.6 28.3 23.0 13.3 53.5 28.6 30.5 5.2 12.8 46.0 15.0 24.5 72.1 43.6 154.0 291.5 48.4 17.2 14.3 28.6 60.5 CTSV "CTSL2, CTSU" ENSG00000136943 "Cathepsin V" O60911 9 97029677-97156556 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "lymphoid tissue: 643.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 63.7;Cytotrophoblasts: 122.3;Extravillous trophoblasts: 153.0;Granulosa cells: 54.2;Syncytiotrophoblasts: 67.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 4 "plasmacytoid DC: 15.1" "Lineage enriched" "Detected in many" 4 "dendritic cells: 15.1" "Group enriched" "Detected in many" 8 "BEWO: 592.6;SuSa: 739.0" "Low region specificity" "Detected in all" CAB017112 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 370000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoli fibrillar center, Cytosol" "Nucleoplasm, Plasma membrane" "CAB017112: " "unprognostic (2.40e-1)" "unprognostic (2.74e-2)" "unprognostic (1.50e-1)" "prognostic favorable (8.41e-4)" "unprognostic (7.29e-2)" "unprognostic (5.59e-2)" "prognostic unfavorable (2.83e-5)" "unprognostic (7.04e-3)" "unprognostic (6.06e-2)" "unprognostic (1.39e-2)" "prognostic unfavorable (2.87e-4)" "unprognostic (1.86e-2)" "unprognostic (1.78e-1)" "unprognostic (2.41e-2)" "unprognostic (1.33e-1)" "unprognostic (3.04e-3)" "prognostic unfavorable (2.39e-4)" 0.2 0.2 0.6 0.3 0.7 0.3 5.8 0.8 1.6 43.1 0.8 2.9 1.1 2.8 1.7 19.8 1.3 0.5 0.1 0.6 0.5 21.3 0.2 0.9 0.1 0.7 0.6 0.2 2.1 1.4 1.5 16.8 0.6 0.7 3.2 17.2 9.4 0.1 0.7 52.5 0.4 0.8 0.5 0.2 2.8 65.8 0.6 643.6 1.3 0.1 6.0 0.4 20.1 1.0 37.1 5.2 12.1 33.1 0.6 0.0 592.6 0.5 0.0 7.1 4.7 81.0 37.7 0.3 2.8 0.5 50.5 67.2 58.8 43.9 9.7 0.1 4.4 0.8 1.9 3.1 0.2 0.1 3.3 0.0 9.2 1.5 0.8 0.9 2.4 8.5 0.5 0.2 14.4 15.2 0.9 0.3 76.2 78.9 10.7 0.0 27.3 0.1 11.4 3.7 2.4 3.6 39.1 13.1 13.2 739.0 21.1 3.2 0.0 1.0 23.6 0.2 3.5 5.7 20.6 0.8 1.6 0.4 4.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.1 0.0 0.2 3.3 0.0 15.1 0.0 0.1 0.6 0.7 0.8 1.6 0.6 0.5 0.7 0.6 0.6 0.5 0.6 1.0 0.9 0.0 1.1 0.3 0.9 30.3 13.0 63.7 19.9 4.6 13.1 9.9 1.3 0.0 17.4 1.8 10.4 122.3 6.9 4.7 1.9 1.8 2.6 15.0 2.9 1.8 1.8 0.0 0.6 0.8 153.0 3.2 0.0 24.0 0.0 54.2 0.4 0.0 13.6 0.0 0.9 1.5 10.2 0.8 3.0 8.2 4.1 2.4 0.0 0.0 0.2 6.5 0.0 0.0 3.5 0.5 10.5 1.2 0.0 8.1 0.1 22.1 4.2 36.6 6.6 1.4 3.6 46.7 33.7 8.2 11.9 67.3 0.5 0.7 4.2 8.4 CXCR2 "CD182, CMKAR2, IL8RB" ENSG00000180871 "C-X-C motif chemokine receptor 2" P25025 2 218125289-218137251 "Cancer-related genes, CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 27.2;lymphoid tissue: 40.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 10.5;dendritic cells: 12.9;granulocytes: 6.3;NK-cells: 40.2;Squamous epithelial cells: 11.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 52 "neutrophil: 3273.9" "Lineage enriched" "Detected in many" 111 "granulocytes: 3273.9" "Group enriched" "Detected in some" 11 "BEWO: 14.5;HL-60: 8.2;HMC-1: 16.5;THP-1: 15.3;U-937: 15.1" "Low region specificity" "Detected in all" "CAB016268, HPA031999, HPA032017" Enhanced Supported "Nucleoplasm,Plasma membrane,Microtubules,Mitotic spindle" Yes NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Nucleoplasm, Microtubules, Mitotic spindle" "CAB016268: AB_626893, HPA031999: AB_2674105, HPA032017: AB_2674112" "unprognostic (4.89e-2)" "unprognostic (2.01e-1)" "unprognostic (5.63e-2)" "unprognostic (1.10e-2)" "unprognostic (1.58e-1)" "unprognostic (3.13e-1)" "unprognostic (1.33e-1)" "unprognostic (2.13e-1)" "unprognostic (5.96e-2)" "unprognostic (1.22e-2)" "unprognostic (5.67e-2)" "unprognostic (1.41e-1)" "unprognostic (7.54e-2)" "unprognostic (1.04e-1)" "unprognostic (7.23e-2)" "unprognostic (8.18e-2)" "unprognostic (5.48e-2)" 13.8 1.5 0.3 40.0 0.6 7.3 0.8 0.2 2.6 4.5 0.1 0.9 0.2 0.4 1.3 27.2 2.9 7.8 1.0 0.3 0.1 0.4 2.4 6.5 0.7 0.6 0.5 0.4 2.9 0.4 0.2 4.6 1.4 0.6 0.7 0.0 3.0 3.8 0.5 4.8 1.2 2.4 0.3 27.3 0.7 0.2 0.5 2.8 0.6 11.6 3.0 7.8 7.3 0.4 0.0 0.0 0.1 0.0 0.0 0.0 14.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.2 16.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 1.3 0.2 0.0 0.0 0.4 0.0 1.3 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.5 0.0 15.3 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 15.1 0.0 63.5 29.5 50.3 28.8 7.4 0.4 0.2 1.3 7.3 13.5 0.2 1.1 9.9 3273.9 6.8 3.6 25.0 0.5 17.4 0.3 0.6 0.2 2.6 0.3 0.1 0.6 0.5 1.4 0.3 0.5 0.4 0.0 0.0 10.5 0.0 0.1 0.0 0.9 0.2 0.0 0.0 0.0 0.4 0.2 0.0 1.9 0.0 0.0 0.7 12.9 0.0 0.0 0.0 0.0 0.2 0.1 0.6 0.0 0.0 0.0 0.0 0.5 1.2 0.0 0.0 6.3 3.3 0.0 0.0 1.6 0.0 0.0 0.0 0.0 2.2 1.6 0.0 0.0 2.8 0.0 1.0 3.7 0.0 40.2 0.0 0.1 0.0 2.2 0.0 1.4 0.1 0.0 0.1 0.3 0.0 0.0 0.4 0.4 0.0 0.0 11.6 0.1 0.3 4.1 0.1 0.1 1.9 CYP20A1 CYP-M ENSG00000119004 "Cytochrome P450 family 20 subfamily A member 1" Q6UW02 2 203238977-203306026 "Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA055872, HPA058461" Uncertain Uncertain "Nucleoplasm,Plasma membrane,Cell Junctions,Actin filaments" No No "Cluster 24: B-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane, Cell Junctions, Actin filaments" Nucleoplasm "HPA055872: AB_2682951, HPA058461: AB_2683725" "unprognostic (4.72e-2)" "unprognostic (2.06e-2)" "unprognostic (1.20e-2)" "unprognostic (2.14e-2)" "unprognostic (1.42e-1)" "unprognostic (3.06e-2)" "unprognostic (5.21e-2)" "unprognostic (2.58e-2)" "unprognostic (4.21e-2)" "unprognostic (2.62e-2)" "unprognostic (4.53e-2)" "unprognostic (4.42e-2)" "unprognostic (7.64e-3)" "unprognostic (9.39e-2)" "unprognostic (2.18e-1)" "unprognostic (1.23e-2)" "unprognostic (1.95e-3)" 3.1 3.2 3.1 2.1 4.3 2.2 2.4 4.1 3.4 2.7 4.2 3.6 2.1 2.3 2.4 2.4 1.9 3.2 1.7 2.7 3.0 6.1 4.6 3.5 3.9 4.5 3.8 3.8 3.1 2.9 0.9 3.4 3.8 3.5 3.2 1.7 2.3 2.1 2.6 3.8 2.6 3.2 2.9 3.7 3.7 2.9 4.2 2.2 8.0 1.3 2.9 3.2 1.0 5.7 2.8 4.7 2.9 2.9 12.1 2.9 2.5 5.0 3.3 2.4 1.7 9.1 5.2 1.9 3.8 4.8 4.4 4.0 1.9 2.7 4.6 2.9 1.0 6.1 3.0 3.5 7.2 6.4 3.3 5.5 2.2 5.7 4.9 2.1 6.4 2.8 8.0 9.9 5.1 4.2 4.3 3.7 7.7 2.3 4.2 3.5 3.7 4.5 3.2 9.2 2.0 2.2 0.4 4.0 5.5 3.3 2.7 4.8 8.5 8.4 2.5 4.0 4.1 5.2 4.4 2.3 6.4 2.8 3.6 5.7 5.2 2.1 6.5 5.6 7.1 6.1 8.0 5.9 2.3 9.6 5.9 3.5 3.0 4.9 6.5 7.4 8.0 4.3 3.1 4.3 4.1 3.4 2.7 3.0 4.5 3.8 3.8 2.9 4.2 5.7 41.2 16.0 33.2 24.2 55.5 12.4 41.6 20.2 29.6 42.0 17.1 17.8 33.6 50.1 33.8 16.5 58.4 33.4 55.8 40.3 11.7 18.3 96.6 24.2 33.6 40.5 45.4 45.5 12.1 20.3 23.0 49.0 53.0 23.7 29.1 65.4 88.2 50.4 37.9 50.5 20.5 33.0 22.4 38.1 22.5 21.9 123.0 35.8 7.2 34.7 44.5 32.4 74.2 24.1 39.1 15.2 30.6 83.8 51.7 33.6 30.8 26.2 23.5 70.5 65.7 76.6 45.7 104.5 64.1 25.4 13.4 40.8 54.4 59.7 32.8 28.7 DCAF13 "DKFZP564O0463, Gm83, HSPC064, Sof1, WDSOF1" ENSG00000164934 "DDB1 and CUL4 associated factor 13" Q9NV06 8 103414714-103443453 "Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing, Ubl conjugation pathway" Ribonucleoprotein "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044504 Uncertain Supported "Nucleoplasm,Nucleoli,Cell Junctions,Centrosome,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 23: Testis - Cell cycle regulation" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nucleoli" "Cell Junctions, Centrosome, Cytosol" "HPA044504: AB_2678963" "prognostic unfavorable (4.06e-4)" "unprognostic (4.39e-2)" "unprognostic (1.70e-1)" "unprognostic (4.46e-3)" "unprognostic (3.57e-2)" "unprognostic (7.86e-3)" "prognostic unfavorable (8.05e-6)" "unprognostic (5.92e-3)" "unprognostic (1.97e-1)" "unprognostic (1.27e-2)" "unprognostic (5.54e-3)" "unprognostic (2.31e-2)" "prognostic unfavorable (2.85e-4)" "unprognostic (1.53e-1)" "unprognostic (1.55e-1)" "unprognostic (6.42e-2)" "unprognostic (8.63e-2)" 16.7 19.2 10.3 22.9 11.0 15.2 23.9 11.3 15.6 17.7 12.8 20.7 16.1 16.2 19.1 21.3 18.0 12.7 16.2 10.9 11.1 32.4 20.7 12.9 24.7 10.8 13.7 13.6 18.5 20.0 15.6 18.7 11.4 14.7 21.4 13.8 14.3 12.8 18.8 15.7 14.5 18.2 11.3 14.3 15.6 32.2 10.4 24.7 18.1 16.0 30.5 33.6 14.6 11.9 96.5 84.2 76.9 79.0 54.7 62.7 57.6 70.1 53.2 64.4 65.9 83.1 90.9 132.2 116.1 73.3 64.0 69.9 105.8 89.0 124.1 127.7 74.9 183.0 48.0 95.9 62.2 76.1 75.7 51.8 59.9 95.9 157.5 40.3 91.4 89.6 125.3 56.7 99.9 78.0 144.9 79.3 118.0 268.9 129.6 92.6 93.3 136.4 95.3 78.6 97.6 92.3 43.5 67.3 83.1 67.4 103.9 51.2 60.6 65.3 105.3 85.5 94.7 61.7 116.5 188.0 88.0 162.8 85.7 19.6 37.6 22.1 35.5 46.5 48.8 60.8 37.5 38.2 54.4 50.8 37.0 38.2 4.2 52.8 35.2 28.3 58.0 44.9 10.3 11.0 11.3 15.6 10.9 11.1 10.8 13.7 11.4 11.3 10.4 11.9 40.0 16.0 17.0 9.1 39.7 79.5 76.6 92.4 38.1 19.6 21.6 24.9 20.8 12.8 53.8 33.1 25.0 57.9 34.8 11.0 39.2 55.0 54.6 26.9 35.4 39.9 14.5 22.1 9.5 48.4 75.0 37.4 17.9 24.7 40.6 49.3 17.5 16.9 42.7 16.8 9.0 17.5 69.2 14.8 23.9 16.7 24.2 22.9 26.6 11.2 28.5 28.8 27.8 16.1 20.0 43.6 12.3 17.7 30.3 51.1 24.3 79.1 36.0 23.7 13.1 50.2 48.0 102.0 86.3 37.1 77.0 33.9 33.1 41.7 28.1 56.9 DIMT1 "DIMT1L, HSA9761" ENSG00000086189 "DIMT1 rRNA methyltransferase and ribosome maturation factor" Q9UNQ2 5 62347284-62403943 "Enzymes, Predicted intracellular proteins" "rRNA processing" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Prostatic glandular cells: 104.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042944 Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 25: RPMI-8226 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoli, Nucleoli rim" "Nucleoplasm, Cytosol" "HPA042944: AB_2678234" "unprognostic (1.58e-1)" "unprognostic (2.27e-1)" "unprognostic (6.02e-3)" "unprognostic (7.16e-2)" "unprognostic (8.95e-3)" "unprognostic (1.73e-2)" "prognostic unfavorable (6.93e-4)" "unprognostic (8.88e-2)" "unprognostic (1.18e-2)" "unprognostic (1.62e-1)" "unprognostic (5.31e-2)" "unprognostic (3.70e-1)" "prognostic unfavorable (8.90e-12)" "unprognostic (8.89e-2)" "unprognostic (2.89e-1)" "unprognostic (1.49e-1)" "unprognostic (5.15e-2)" 16.3 13.6 6.5 13.3 6.5 9.1 19.7 6.7 9.6 17.2 6.4 10.9 8.5 14.6 13.9 17.5 14.5 14.2 17.7 6.6 6.8 10.6 15.4 9.8 15.9 6.7 6.7 15.5 19.3 13.3 10.3 17.3 6.7 15.9 12.0 2.9 15.2 16.2 9.7 8.5 8.8 21.0 6.7 13.3 8.5 8.2 6.6 15.0 13.4 12.8 16.8 26.0 11.4 6.7 33.1 19.9 24.2 44.1 37.7 57.4 35.0 57.3 33.7 57.3 55.8 45.1 36.3 61.4 48.4 61.9 45.4 20.2 38.7 35.8 61.3 46.4 34.0 27.2 15.0 33.8 48.1 32.4 34.7 46.7 31.1 54.1 57.3 28.1 46.1 37.0 49.3 27.9 47.3 43.5 50.1 58.6 36.1 18.9 49.7 28.2 33.3 119.2 45.8 29.9 31.5 19.8 38.5 32.2 35.5 19.6 27.0 29.2 40.3 21.0 29.5 33.7 71.2 27.4 46.7 62.6 27.0 61.6 45.1 7.9 5.3 2.7 6.7 9.1 12.7 10.4 11.2 9.1 9.3 6.1 11.6 9.7 0.1 7.7 6.8 12.1 7.8 6.3 6.5 6.5 6.7 9.6 6.6 6.8 6.7 6.7 6.7 6.7 6.6 6.7 25.3 3.2 9.5 6.5 37.8 50.9 90.3 54.8 69.4 6.2 29.9 20.2 35.3 17.2 36.3 14.7 10.4 45.3 21.9 5.0 21.5 28.6 10.1 23.8 28.3 32.0 4.8 20.4 11.1 22.5 48.1 35.6 13.7 23.2 13.3 13.3 17.5 13.4 33.1 0.0 10.5 12.1 32.6 16.4 22.8 4.4 28.9 18.5 28.4 2.8 19.7 7.4 13.4 8.0 12.9 19.8 7.5 20.3 29.3 104.3 4.0 32.5 24.0 4.7 6.6 51.8 49.8 16.5 20.4 58.7 37.8 35.7 31.1 28.6 18.3 76.6 DMRT2 ENSG00000173253 "Doublesex and mab-3 related transcription factor 2" Q9Y5R5 9 1049858-1057552 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 41.2;lymphoid tissue: 20.9;parathyroid gland: 46.4" "Cell type enhanced" "Detected in some" "Distal tubular cells: 115.4;Ionocytes: 46.8;Skeletal myocytes: 22.7" "Group enriched" "Detected in many" 4 "lung cancer: 3.0;renal cancer: 9.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 3.8;RH-30: 5.0;RPMI-8226: 19.4;SK-MEL-30: 5.2;THP-1: 3.6;WM-115: 3.6" "Low region specificity" "Detected in some" "Region enhanced" "Detected in single" "cerebral cortex: 1.1" "HPA003498, HPA029297" Uncertain Approved "Nucleoplasm,Nucleoli,Vesicles,Centriolar satellite" NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli" "Vesicles, Centriolar satellite" "HPA003498: , HPA029297: AB_10600905" "unprognostic (5.67e-2)" "unprognostic (2.20e-3)" "unprognostic (3.24e-2)" "unprognostic (8.88e-2)" "unprognostic (1.32e-1)" "unprognostic (7.10e-2)" "unprognostic (1.46e-1)" "unprognostic (1.65e-1)" "unprognostic (3.13e-1)" "unprognostic (7.43e-2)" "unprognostic (1.74e-1)" "unprognostic (1.43e-3)" "unprognostic (8.93e-2)" "unprognostic (8.62e-2)" "unprognostic (4.93e-2)" "unprognostic (1.27e-3)" 4.7 0.1 1.7 0.1 3.4 0.0 5.3 3.1 2.7 0.1 0.2 1.6 0.0 0.1 1.1 0.3 0.6 0.0 0.1 1.9 1.9 41.2 0.0 3.1 0.2 3.0 3.1 0.0 0.0 46.4 0.5 0.2 2.9 0.3 0.9 0.4 1.3 1.4 13.3 0.3 0.1 0.0 1.7 0.0 0.0 0.8 2.8 20.9 0.1 2.5 0.1 0.0 0.2 8.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 3.8 0.9 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 5.0 19.4 0.0 0.8 2.9 0.0 0.0 0.0 5.2 0.3 0.1 3.6 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 3.4 3.1 2.7 1.9 1.9 3.0 3.1 2.9 1.7 2.8 8.5 0.5 0.0 0.0 0.3 0.2 0.5 0.6 1.8 0.0 0.1 0.1 0.3 0.5 0.0 0.5 0.0 0.0 0.1 0.1 1.8 115.4 0.0 4.3 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 4.4 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 1.0 46.8 0.0 1.1 0.4 0.6 0.2 3.6 0.0 0.0 0.3 0.0 0.5 11.1 0.0 1.9 0.0 0.4 0.2 0.0 0.4 0.6 2.4 0.0 22.7 0.7 4.0 3.0 0.2 0.1 0.1 0.1 0.0 1.8 0.4 DNAL4 "dJ327J16, PIG27" ENSG00000100246 "Dynein axonemal light chain 4" O96015 22 38778508-38794198 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 124.1;Late spermatids: 210.7;Spermatocytes: 77.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 64.0" "Low region specificity" "Detected in all" HPA003647 Approved Approved Nucleoplasm,Nucleoli,Centrosome,Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 31: Spermatids - Spermatogenesis" Centrosome "Nucleoplasm, Nucleoli, Cytosol" "HPA003647: AB_1078712" "unprognostic (8.45e-2)" "unprognostic (8.15e-3)" "unprognostic (2.35e-1)" "unprognostic (3.14e-3)" "unprognostic (3.74e-1)" "unprognostic (1.52e-1)" "unprognostic (6.46e-3)" "unprognostic (2.81e-1)" "unprognostic (3.32e-1)" "unprognostic (1.81e-1)" "unprognostic (2.06e-1)" "unprognostic (2.07e-1)" "prognostic favorable (1.20e-6)" "unprognostic (1.60e-1)" "unprognostic (1.10e-1)" "unprognostic (8.00e-2)" "unprognostic (4.83e-2)" 11.3 18.0 29.1 6.7 32.3 4.4 14.5 21.0 36.5 18.3 23.2 12.9 7.9 12.2 15.0 18.9 35.4 12.9 13.7 29.2 28.3 24.4 11.1 13.9 8.1 22.1 23.3 17.5 21.3 31.1 30.9 9.9 22.1 18.3 9.6 13.8 18.1 12.1 7.0 17.5 9.8 7.5 22.0 11.4 16.4 65.5 28.0 14.3 25.4 6.2 8.3 14.2 15.5 24.5 17.9 8.9 17.5 15.5 21.8 21.7 0.0 7.5 14.0 11.4 12.2 5.7 20.1 4.5 15.7 10.7 13.1 8.3 11.0 20.5 7.7 11.4 14.8 2.6 2.5 6.6 34.9 14.5 3.7 17.1 64.0 14.9 26.8 29.7 16.6 22.1 5.3 8.5 13.8 21.9 13.6 14.0 6.8 26.3 7.4 12.8 7.5 5.9 23.7 10.8 24.3 13.5 15.4 11.5 30.7 12.1 20.7 13.7 9.8 10.1 10.1 15.5 7.5 5.3 1.8 2.1 29.9 4.9 9.8 15.0 8.5 11.9 11.2 8.9 13.8 7.1 9.3 10.2 8.7 10.6 10.5 9.0 15.0 16.2 11.3 13.2 9.3 7.5 29.1 32.3 21.0 36.5 29.2 28.3 22.1 23.3 22.1 22.0 28.0 24.5 8.2 6.4 10.5 5.5 5.1 5.6 13.4 18.9 10.2 15.0 20.6 17.8 4.3 14.3 15.2 3.7 2.1 27.6 9.7 10.9 31.3 28.4 124.1 56.4 11.8 8.5 12.6 11.2 11.0 15.5 21.2 10.1 6.1 10.5 15.2 20.3 12.8 3.8 13.7 11.8 10.6 14.7 14.2 4.4 2.8 210.7 11.8 6.5 8.8 4.7 5.7 18.9 8.2 6.6 5.1 18.4 9.1 7.5 1.3 9.8 8.5 20.0 41.0 15.4 6.6 6.6 11.6 77.7 20.0 9.1 10.5 19.8 6.0 20.1 13.2 12.0 DNTTIP1 "C20orf167, dJ447F3.4, Tdif1" ENSG00000101457 "Deoxynucleotidyltransferase terminal interacting protein 1" Q9H147 20 45791954-45811427 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 124.8" "Group enriched" "Detected in all" 6 "dendritic cells: 43.3;granulocytes: 124.8;monocytes: 50.9" "Cell line enhanced" "Detected in all" "PC-3: 280.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045496 Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 52: Eosinophils - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 3: Monocytes - Immune response regulation" "Nucleoli, Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA045496: " "unprognostic (7.77e-2)" "unprognostic (2.19e-1)" "unprognostic (2.07e-1)" "unprognostic (4.52e-2)" "unprognostic (2.50e-1)" "unprognostic (3.05e-2)" "prognostic unfavorable (1.79e-5)" "unprognostic (6.29e-2)" "unprognostic (7.16e-2)" "unprognostic (1.85e-1)" "unprognostic (5.81e-3)" "unprognostic (5.63e-2)" "prognostic unfavorable (1.90e-6)" "unprognostic (3.18e-1)" "unprognostic (1.54e-1)" "unprognostic (1.19e-1)" "unprognostic (1.30e-1)" 19.9 19.4 22.8 24.7 23.2 44.1 20.0 23.3 26.1 21.0 23.9 33.2 17.5 27.2 25.0 19.5 24.7 21.7 27.3 23.1 24.2 19.2 19.3 22.3 23.7 23.2 24.3 20.6 15.8 26.1 20.8 23.1 23.4 22.0 38.7 21.7 19.4 22.8 62.0 28.2 21.0 24.4 23.4 25.3 24.6 30.4 23.8 30.1 19.6 31.0 28.0 34.0 19.3 24.4 79.8 41.6 42.1 40.2 31.7 34.1 43.7 29.2 47.1 92.7 83.4 134.8 126.1 32.8 93.2 42.9 147.1 58.4 37.3 62.8 61.1 18.0 47.2 36.0 45.2 87.2 64.4 70.0 56.7 34.4 58.0 60.8 58.2 42.4 55.1 46.9 33.9 32.6 56.0 107.5 57.9 108.2 28.7 44.8 280.7 46.0 52.3 34.4 47.4 37.9 39.5 35.6 59.7 48.2 65.2 32.7 47.6 111.4 32.6 55.4 41.1 54.0 71.0 35.5 24.8 41.0 120.5 44.8 48.1 16.7 50.9 71.0 4.1 22.0 4.2 12.0 5.5 7.0 43.3 11.1 10.1 4.7 124.8 3.3 13.6 16.6 9.3 13.5 22.8 23.2 23.3 26.1 23.1 24.2 23.2 24.3 23.4 23.4 23.8 24.4 21.2 16.0 22.9 10.1 22.0 25.5 44.8 43.1 22.2 19.8 20.3 23.0 19.9 21.5 37.1 25.8 4.2 60.7 14.3 37.2 50.9 57.6 37.9 35.1 19.4 22.6 22.2 9.7 11.2 75.4 43.0 25.7 26.5 20.6 6.3 26.4 25.0 16.6 70.8 20.2 9.5 92.7 59.0 26.3 34.7 15.7 28.3 32.4 16.0 11.2 68.3 53.1 15.5 7.5 10.6 105.0 50.5 27.1 21.9 38.2 33.3 44.2 48.0 29.7 0.0 20.8 26.5 92.9 35.4 19.4 27.6 57.7 16.3 32.9 34.8 60.7 DOCK8 "FLJ00026, FLJ00152, FLJ00346, ZIR8" ENSG00000107099 "Dedicator of cytokinesis 8" Q8NF50 9 214854-465259 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 45.0;lymphoid tissue: 64.8" "Cell type enhanced" "Detected in many" "Microglial cells: 506.8;monocytes: 134.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 173.6" "Group enriched" "Detected in all" 4 "dendritic cells: 53.0;granulocytes: 173.6;monocytes: 84.2" "Cell line enhanced" "Detected in many" "Daudi: 52.9;HL-60: 53.3;MOLT-4: 50.1;NB-4: 83.7;REH: 61.9;RT4: 54.3;THP-1: 158.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003218, HPA073349" Enhanced Approved Nucleoplasm,Centrosome,Mitochondria,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Centrosome "Nucleoplasm, Mitochondria, Cytosol" "HPA003218: AB_1078695, HPA073349: " "unprognostic (1.56e-1)" "unprognostic (5.90e-2)" "unprognostic (7.75e-2)" "unprognostic (7.55e-3)" "unprognostic (3.31e-1)" "unprognostic (6.28e-3)" "unprognostic (1.79e-1)" "unprognostic (8.12e-2)" "unprognostic (2.72e-2)" "unprognostic (6.72e-2)" "unprognostic (1.90e-1)" "unprognostic (3.89e-2)" "prognostic favorable (9.21e-6)" "unprognostic (2.91e-1)" "unprognostic (3.91e-2)" "unprognostic (3.91e-1)" "prognostic favorable (6.89e-6)" 11.0 13.3 4.3 35.7 4.4 42.2 7.3 5.2 3.9 4.3 45.0 7.3 7.3 3.0 2.9 7.2 4.3 14.6 2.0 4.0 5.9 16.5 6.1 19.7 51.1 8.8 7.6 2.0 4.2 7.7 2.6 15.3 9.1 5.1 7.3 4.5 4.6 2.8 1.0 3.0 15.4 6.2 9.3 45.6 9.5 7.5 8.8 64.8 4.9 2.5 49.6 14.8 3.3 12.8 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 0.0 1.6 1.4 52.9 3.9 0.0 0.0 2.3 0.8 0.3 0.0 18.2 2.3 0.1 0.0 0.2 0.0 53.3 7.1 0.2 9.3 0.0 0.2 0.0 0.0 0.0 11.8 25.9 0.0 3.2 50.1 83.7 0.2 0.2 0.7 61.9 0.1 21.3 0.2 54.3 0.1 0.0 0.0 0.6 3.6 1.0 1.4 158.0 10.2 0.0 0.4 0.7 0.1 10.3 0.1 0.0 0.1 33.3 0.9 65.1 56.9 73.5 12.2 52.0 10.2 25.2 15.7 13.8 53.0 23.2 11.3 11.1 173.6 24.1 84.2 13.8 15.6 22.6 4.3 4.4 5.2 3.9 4.0 5.9 8.8 7.6 9.1 9.3 8.8 12.8 5.0 9.6 33.5 2.3 112.6 6.4 2.5 1.2 45.5 3.6 12.3 10.8 2.3 18.6 4.9 7.3 77.2 70.9 101.9 1.5 1.9 1.0 33.4 1.9 0.7 9.8 8.4 35.1 1.9 6.5 4.3 5.3 12.8 3.2 24.6 12.7 2.9 2.6 58.4 0.0 4.2 12.9 2.0 115.0 49.4 14.8 3.1 107.7 8.8 506.8 134.3 1.1 74.2 4.5 2.2 1.4 24.9 0.4 94.6 1.5 1.2 12.8 8.0 4.2 13.1 30.2 20.6 22.1 13.3 9.4 3.8 42.7 111.6 1.1 1.3 3.4 DOK2 "Dok-2, p56dok-2" ENSG00000147443 "Docking protein 2" O60496 8 21908873-21913690 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 25.6;lymphoid tissue: 40.9" "Cell type enhanced" "Detected in many" "dendritic cells: 130.6;Hofbauer cells: 131.8;Kupffer cells: 171.8;Langerhans cells: 288.4;Macrophages: 181.5;NK-cells: 344.0;T-cells: 147.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 1565.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 25.3;HEL: 54.3;HMC-1: 119.8;JURKAT: 22.3;THP-1: 43.1;U-937: 42.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB004379, HPA005507, HPA066571" Enhanced Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus,Cytosol" NA NA 220000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Nucleoplasm, Nuclear bodies, Golgi apparatus" "CAB004379: AB_627449, HPA005507: , HPA066571: AB_2732749" "unprognostic (5.39e-2)" "unprognostic (8.84e-3)" "unprognostic (8.72e-3)" "unprognostic (1.74e-3)" "unprognostic (2.14e-2)" "unprognostic (2.30e-3)" "unprognostic (1.34e-1)" "unprognostic (7.22e-2)" "prognostic favorable (4.31e-4)" "unprognostic (2.22e-1)" "unprognostic (4.19e-2)" "unprognostic (1.90e-1)" "prognostic unfavorable (2.20e-4)" "unprognostic (1.88e-1)" "unprognostic (1.24e-2)" "unprognostic (3.19e-1)" "unprognostic (2.80e-1)" 9.5 5.0 1.1 26.5 1.2 19.5 5.0 1.2 2.3 1.9 2.5 5.5 7.0 2.2 0.5 2.3 3.5 6.5 3.5 1.3 1.3 3.0 6.1 25.6 26.3 1.4 1.5 1.4 1.9 0.5 1.1 7.9 1.5 2.3 3.6 0.0 3.4 1.5 2.0 2.3 9.5 6.9 1.2 40.9 6.8 1.6 4.5 16.4 2.4 1.6 7.8 8.4 2.3 1.5 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.3 0.0 54.3 0.0 0.1 0.0 0.4 119.8 0.0 0.0 0.0 0.0 0.0 0.0 22.3 0.8 5.0 0.0 0.0 0.9 8.7 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.1 0.3 0.0 0.1 0.2 0.1 0.2 0.1 0.3 1.4 42.0 0.2 577.6 484.3 1565.6 398.3 624.0 184.5 14.5 274.3 304.8 421.9 6.6 151.0 185.9 37.2 307.6 580.7 7.6 597.2 810.3 1.1 1.2 1.2 2.3 1.3 1.3 1.4 1.5 1.5 1.2 4.5 1.5 2.0 3.2 18.1 0.0 13.2 11.5 0.6 0.0 0.0 0.0 1.2 1.8 2.1 0.0 1.3 3.7 0.0 0.7 130.6 0.3 0.0 0.1 0.2 0.2 0.5 2.8 0.0 10.5 0.1 0.0 1.0 2.6 3.1 0.4 36.3 0.1 5.7 1.1 131.8 0.0 0.0 0.2 0.0 171.8 288.4 0.6 0.3 181.5 19.6 0.0 74.8 0.0 344.0 0.0 0.0 0.0 0.0 0.0 15.4 0.2 0.0 0.7 1.5 0.0 0.0 0.6 2.5 0.2 4.3 0.7 8.5 1.0 147.4 0.0 0.2 0.8 DOK3 FLJ22570 ENSG00000146094 "Docking protein 3" Q7L591 5 177501904-177511274 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 93.6;lymphoid tissue: 118.4" "Group enriched" "Detected in many" 5 "B-cells: 31.6;granulocytes: 18.3;Hofbauer cells: 55.7;Kupffer cells: 51.1;Macrophages: 38.3;monocytes: 45.4;Plasma cells: 38.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 133.6" "Group enriched" "Detected in many" 6 "B-cells: 37.2;granulocytes: 133.6;monocytes: 77.6" "Cell line enhanced" "Detected in many" "Daudi: 124.0;HMC-1: 87.5;REH: 148.6;U-698: 122.1;U-937: 88.0" "Low region specificity" "Detected in many" HPA077312 Enhanced Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge,Cytosol" Yes NA 240000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "Nucleoplasm, Cytokinetic bridge, Cytosol" "HPA077312: AB_2732339" "unprognostic (2.21e-2)" "unprognostic (1.14e-2)" "unprognostic (2.05e-2)" "unprognostic (5.74e-3)" "unprognostic (2.32e-2)" "unprognostic (1.34e-3)" "unprognostic (4.17e-2)" "unprognostic (2.20e-1)" "unprognostic (8.00e-2)" "unprognostic (1.32e-1)" "unprognostic (1.21e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (3.82e-11)" "unprognostic (1.34e-1)" "unprognostic (7.25e-2)" "unprognostic (1.55e-1)" "unprognostic (3.78e-2)" 11.0 6.1 5.2 30.2 6.2 93.6 4.4 6.5 7.9 3.2 6.3 8.2 6.5 3.4 1.7 5.5 7.8 4.3 4.1 6.0 7.0 5.0 6.5 27.1 31.5 11.3 6.8 2.1 4.5 0.8 3.4 7.0 10.5 5.5 3.5 2.1 6.6 2.0 3.6 2.6 28.9 4.5 6.7 118.4 5.9 8.9 9.9 4.3 4.4 4.1 32.3 7.1 4.0 8.1 5.2 7.8 5.4 6.3 3.2 0.4 13.0 4.4 1.1 14.0 12.9 11.0 2.2 124.0 3.2 4.0 6.8 8.9 12.2 7.6 6.9 26.1 14.6 21.3 21.4 2.5 1.0 46.1 87.5 1.6 4.5 16.2 1.6 1.5 1.9 11.4 14.8 50.2 5.1 12.9 2.7 52.5 12.2 1.5 12.9 148.6 9.3 1.2 4.4 5.2 7.4 4.9 2.0 2.1 6.2 4.8 11.7 63.4 2.7 12.3 11.3 6.5 5.4 11.1 15.0 122.1 2.7 88.0 2.2 16.8 62.4 57.0 0.3 61.3 0.6 37.2 0.1 0.3 14.5 19.6 0.1 0.1 133.6 0.5 77.6 1.2 0.0 28.7 5.2 6.2 6.5 7.9 6.0 7.0 11.3 6.8 10.5 6.7 9.9 8.1 1.4 0.0 5.6 1.6 31.6 0.3 0.1 0.4 1.8 0.8 1.0 0.9 0.4 0.0 0.2 0.0 0.0 0.5 0.3 0.2 0.0 0.2 0.0 0.4 0.4 1.9 0.0 6.3 4.1 0.2 0.7 1.2 0.5 0.8 18.3 0.2 7.1 0.8 55.7 0.0 3.5 0.3 0.0 51.1 2.3 0.4 0.6 38.3 1.8 3.7 45.4 0.3 2.1 0.5 0.5 0.0 0.7 1.2 38.3 0.2 0.2 0.1 0.1 0.6 0.0 1.8 0.4 3.0 1.9 0.7 0.3 1.0 2.2 0.3 0.8 0.1 DPPA4 FLJ10713 ENSG00000121570 "Developmental pluripotency associated 4" Q7L190 3 109326141-109337572 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.7;lymphoid tissue: 12.2;testis: 4.1" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 22.3;Erythroid cells: 16.4;Extravillous trophoblasts: 17.2;Spermatogonia: 11.7;Syncytiotrophoblasts: 6.2" "Cancer enriched" "Detected in single" 218 "testis cancer: 59.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 12 "plasmacytoid DC: 7.3" "Lineage enriched" "Detected in single" 12 "dendritic cells: 7.3" "Group enriched" "Detected in some" 4 "HAP1: 89.7;NTERA-2: 327.5;SuSa: 120.7" "Not detected" "Not detected" "Not detected" "Not detected" "CAB020678, HPA035249, HPA035250" Enhanced Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome,Cytosol" Yes NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 5: NTERA-2 - Transcription" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoli, Nucleoli rim" "Nucleoplasm, Mitotic chromosome, Cytosol" "CAB020678: , HPA035249: AB_2674535, HPA035250: AB_2674536" "unprognostic (2.07e-2)" "unprognostic (2.53e-2)" "unprognostic (3.80e-1)" "unprognostic (2.53e-1)" "unprognostic (8.57e-2)" "unprognostic (1.80e-2)" "unprognostic (1.67e-1)" "unprognostic (1.52e-1)" "unprognostic (9.83e-2)" "unprognostic (2.02e-2)" "unprognostic (6.60e-2)" "unprognostic (2.48e-2)" "unprognostic (3.03e-8)" "unprognostic (5.28e-2)" "unprognostic (5.04e-2)" "unprognostic (5.56e-2)" "unprognostic (3.85e-2)" 0.0 0.0 0.0 0.1 0.0 4.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.7 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 4.1 0.0 12.2 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 43.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 89.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 327.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 120.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.1 0.1 0.0 0.5 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 22.3 4.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 16.4 0.1 0.0 17.2 0.5 0.0 0.0 1.3 0.0 0.4 1.6 1.7 0.0 0.1 0.0 0.0 0.3 0.0 0.6 0.3 0.4 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.1 0.7 0.0 0.0 0.9 0.3 0.3 11.7 0.0 0.0 6.2 0.5 0.2 0.0 0.3 DPY19L4 ENSG00000156162 "Dpy-19 like 4" Q7Z388 8 94719703-94793836 "Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatic stellate cells: 65.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024339, HPA024780" Approved Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 52: Non-specific - Transcription" "Plasma membrane" "Nucleoplasm, Nuclear bodies, Cytosol" "HPA024339: , HPA024780: AB_10600869" "unprognostic (1.45e-1)" "unprognostic (2.89e-3)" "unprognostic (3.41e-2)" "prognostic unfavorable (3.73e-4)" "unprognostic (2.28e-1)" "unprognostic (5.54e-2)" "unprognostic (4.94e-2)" "unprognostic (7.17e-2)" "unprognostic (3.18e-2)" "unprognostic (1.04e-1)" "unprognostic (4.72e-2)" "unprognostic (9.38e-2)" "unprognostic (2.25e-1)" "unprognostic (1.48e-2)" "unprognostic (1.74e-1)" "unprognostic (1.39e-2)" "unprognostic (1.55e-1)" 11.5 12.3 7.3 6.6 10.5 5.1 12.5 9.7 9.4 13.6 8.0 8.6 6.7 12.3 10.5 7.6 11.2 10.0 15.4 6.5 10.1 14.5 15.8 9.1 6.9 9.9 9.0 16.7 9.4 26.4 6.4 12.6 10.3 11.6 9.0 13.0 10.2 9.0 7.2 9.4 7.9 9.5 9.6 11.1 13.1 9.6 8.9 7.0 16.1 9.3 5.8 8.6 8.5 14.4 24.4 15.5 26.1 16.4 25.9 33.3 14.4 21.5 20.3 19.8 19.4 7.3 35.0 5.4 25.8 20.8 13.3 25.0 16.0 16.9 32.7 12.2 12.8 25.3 15.1 12.2 30.1 10.9 5.1 22.2 14.0 16.8 16.2 23.2 24.3 16.0 18.0 9.0 23.3 15.3 20.9 20.5 10.2 27.9 17.2 14.8 17.9 10.9 19.1 18.9 12.8 28.7 17.2 3.6 16.8 15.9 22.8 13.6 24.0 20.5 12.6 23.1 18.1 9.9 13.1 14.8 15.4 18.7 29.6 0.7 0.5 0.0 1.0 0.6 1.4 1.2 1.0 1.6 1.0 0.3 1.1 1.4 0.4 1.4 0.6 1.2 0.4 0.7 7.3 10.5 9.7 9.4 6.5 10.1 9.9 9.0 10.3 9.6 8.9 14.4 21.1 16.0 16.3 20.5 6.3 9.8 14.1 11.6 15.9 19.6 16.2 12.1 26.0 11.5 13.0 40.5 4.2 16.7 3.7 8.5 1.9 8.9 2.1 13.7 20.3 19.0 7.3 9.7 13.2 10.0 11.9 20.4 12.2 13.7 3.8 23.1 65.0 27.5 9.6 13.5 18.3 11.5 10.2 14.8 11.9 5.0 17.4 8.3 10.6 25.3 5.5 11.9 9.2 23.6 39.7 13.0 6.4 18.4 7.9 15.6 10.7 10.7 18.8 17.6 6.6 13.4 14.9 11.9 9.8 16.6 12.1 9.2 7.8 32.6 12.0 14.1 DSN1 "C20orf172, dJ469A13.2, hKNL-3, KNL3, MIS13" ENSG00000149636 "DSN1 component of MIS12 kinetochore complex" Q9H410 20 36751791-36773818 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 49.8;Spermatocytes: 115.5;Spermatogonia: 75.1;Syncytiotrophoblasts: 47.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002813, HPA030627" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Nuclear bodies,Kinetochore,Cytosol" Yes Yes "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nucleoli fibrillar center, Nuclear bodies, Kinetochore, Cytosol" "HPA002813: AB_1078343, HPA030627: AB_2732460" "unprognostic (3.60e-2)" "prognostic favorable (4.49e-4)" "unprognostic (5.22e-3)" "unprognostic (1.13e-3)" "unprognostic (2.00e-1)" "unprognostic (4.64e-2)" "prognostic unfavorable (4.16e-5)" "unprognostic (3.93e-1)" "unprognostic (9.35e-2)" "unprognostic (5.51e-2)" "unprognostic (2.98e-2)" "unprognostic (7.66e-2)" "prognostic unfavorable (1.54e-5)" "unprognostic (6.92e-2)" "unprognostic (2.53e-1)" "unprognostic (2.58e-2)" "unprognostic (2.84e-1)" 5.9 9.9 4.2 7.5 4.2 14.3 8.6 3.9 4.5 5.0 5.2 9.2 6.8 4.4 9.3 7.9 4.1 4.4 5.1 4.3 4.4 4.8 9.1 6.3 12.8 4.0 3.9 4.3 4.3 5.5 3.5 8.8 4.1 6.5 10.8 10.7 5.9 6.3 4.0 8.0 7.8 6.3 3.9 9.6 7.3 23.3 4.1 16.4 5.1 4.8 14.3 4.4 4.7 4.7 36.7 29.1 35.7 29.5 14.0 18.0 24.7 42.9 35.1 63.9 70.2 52.5 44.4 39.3 27.4 23.0 69.1 45.8 33.3 32.7 60.3 18.2 22.7 78.3 26.2 36.1 3.0 46.2 34.0 7.0 9.4 43.7 13.8 10.4 31.5 42.4 30.9 33.7 41.7 25.3 59.2 34.5 16.8 63.3 55.1 46.1 109.4 28.4 16.2 20.5 37.8 16.9 52.9 53.7 25.8 26.3 55.9 30.5 16.4 60.1 35.0 56.9 46.1 27.3 39.1 46.4 49.8 40.8 42.6 53.4 6.4 14.5 7.4 11.0 8.4 14.6 8.1 10.3 7.1 18.4 10.1 9.0 11.9 11.1 10.1 46.9 12.2 6.7 4.2 4.2 3.9 4.5 4.3 4.4 4.0 3.9 4.1 3.9 4.1 4.7 6.5 6.4 4.4 1.6 10.3 5.0 11.4 7.6 3.4 8.0 8.7 7.6 5.4 2.8 8.6 5.5 29.2 49.8 9.8 9.2 7.9 6.8 10.6 5.5 5.9 8.1 2.4 22.1 6.3 6.4 30.4 8.4 20.9 9.4 3.8 21.8 7.9 6.2 14.7 6.7 4.4 13.6 4.1 6.3 4.6 8.0 8.7 6.7 1.8 5.6 7.4 6.0 7.2 3.0 3.6 5.1 5.4 7.5 22.9 7.1 7.7 3.6 8.2 17.5 0.0 5.3 8.2 115.5 75.1 12.3 7.2 47.5 7.7 6.9 13.6 11.0 DTWD1 "MDS009, MGC111207" ENSG00000104047 "DTW domain containing 1" Q8N5C7 15 49621037-49656232 "Enzymes, Predicted intracellular proteins" "tRNA processing" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042214 Uncertain Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome,Vesicles" Yes No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoli rim" "Nucleoplasm, Mitotic chromosome, Vesicles" "HPA042214: AB_2677903" "unprognostic (2.60e-2)" "unprognostic (1.73e-1)" "unprognostic (3.00e-1)" "unprognostic (3.70e-4)" "unprognostic (8.12e-2)" "unprognostic (2.37e-1)" "unprognostic (1.82e-1)" "unprognostic (9.87e-2)" "unprognostic (4.44e-3)" "unprognostic (4.25e-2)" "unprognostic (5.42e-2)" "unprognostic (1.48e-1)" "unprognostic (2.32e-3)" "unprognostic (1.02e-1)" "unprognostic (7.85e-2)" "unprognostic (2.80e-2)" "unprognostic (2.35e-1)" 19.6 11.8 7.7 13.0 10.1 5.4 18.2 8.2 9.1 27.4 6.5 21.1 7.4 22.6 16.8 13.3 21.1 23.0 11.0 9.0 8.9 11.0 11.5 10.9 12.9 5.7 6.9 22.7 33.3 11.5 9.2 12.8 6.0 15.7 11.9 8.8 21.5 14.7 10.3 12.2 9.1 20.5 6.4 9.0 14.9 9.5 9.9 11.7 17.6 21.1 10.0 20.4 15.9 9.8 10.0 11.9 21.2 11.5 41.3 84.1 16.6 29.3 28.6 36.8 27.5 4.2 8.3 16.7 20.3 38.7 16.8 17.8 15.6 15.8 37.7 10.8 11.2 13.8 23.5 14.5 29.1 18.0 11.1 38.8 20.4 24.3 29.7 32.9 15.5 19.3 26.3 17.3 41.7 23.3 12.3 15.1 12.4 22.6 15.7 17.4 44.7 64.9 12.3 7.1 18.6 14.4 34.7 11.5 27.3 22.1 12.1 25.4 10.7 43.6 17.3 25.6 32.3 13.2 22.2 10.0 37.5 53.9 28.3 8.7 9.7 5.2 6.8 11.7 9.8 9.7 10.3 11.6 12.8 10.1 12.0 11.5 2.6 13.9 15.3 25.3 8.9 6.0 7.7 10.1 8.2 9.1 9.0 8.9 5.7 6.9 6.0 6.4 9.9 9.8 39.9 19.2 15.0 36.6 16.6 19.2 15.4 31.9 18.2 41.8 23.0 34.0 18.8 12.8 22.1 35.0 31.3 23.4 27.1 4.7 31.3 20.1 21.0 27.8 88.1 23.6 15.5 20.8 57.2 21.0 27.7 49.9 20.4 14.1 7.0 29.3 25.4 14.9 19.5 18.5 55.2 19.2 40.7 16.4 14.9 11.2 37.9 16.7 16.0 18.7 10.4 20.3 18.6 33.7 66.1 20.8 10.3 28.2 27.0 21.5 9.5 22.0 37.9 40.0 6.6 35.5 46.7 51.2 44.3 19.6 19.0 9.7 16.2 35.4 17.1 12.7 DUX4 ENSG00000260596 "Double homeobox 4" Q9UBX2 4 190173774-190185942 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors, Transporters" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.0" "Group enriched" "Detected in some" 26 "Early spermatids: 4.9;Late spermatids: 5.6" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 1.5;U-2 OS: 2.2;U-266/70: 4.7;U-266/84: 6.9;U-698: 1.5" "Low region specificity" "Detected in some" HPA058451 Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Nucleoli" "Golgi apparatus, Cytosol" "HPA058451: AB_2683722" 0.0 0.1 0.3 0.0 0.5 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.7 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 2.2 0.4 0.0 4.7 6.9 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 1.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 EEF1AKMT2 "C10orf138, Efm4, METTL10" ENSG00000203791 "EEF1A lysine methyltransferase 2" Q5JPI9 10 124748149-124791887 "Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 29.1;Distal tubular cells: 66.5;Extravillous trophoblasts: 29.8;Proximal tubular cells: 30.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA050138 Approved Supported "Nucleoplasm,Nuclear bodies,Vesicles,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Nuclear bodies, Vesicles, Cytosol" "HPA050138: AB_2681030" "unprognostic (1.64e-3)" "unprognostic (3.42e-2)" "unprognostic (1.34e-1)" "unprognostic (9.75e-2)" "unprognostic (7.19e-2)" "unprognostic (1.17e-1)" "unprognostic (2.33e-2)" "unprognostic (2.29e-3)" "unprognostic (9.04e-3)" "unprognostic (9.76e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (4.82e-4)" "unprognostic (3.90e-2)" "unprognostic (4.44e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (2.53e-4)" "unprognostic (9.09e-2)" 4.8 3.8 3.0 2.1 3.3 3.6 5.3 4.8 4.2 4.6 3.0 3.7 1.8 4.0 4.6 4.0 3.8 2.1 4.1 3.1 3.0 4.9 5.2 3.3 2.5 2.8 3.1 5.5 4.4 4.5 4.3 2.7 2.8 4.3 3.8 2.5 5.1 2.8 4.0 5.0 3.5 2.6 2.7 3.5 3.7 5.6 2.8 3.3 5.1 3.3 3.1 3.4 4.2 3.6 12.6 3.3 4.8 8.0 3.1 8.0 3.1 5.8 7.6 7.4 6.5 4.3 7.1 8.4 3.0 4.7 2.5 3.8 6.8 4.2 11.5 7.0 2.5 6.8 4.2 3.9 6.0 10.9 4.1 3.9 3.9 4.1 9.9 6.2 4.7 7.0 7.6 9.3 9.3 3.7 5.2 8.5 5.9 4.6 4.8 2.3 5.7 2.6 4.6 2.7 1.5 3.8 3.7 6.2 8.7 3.3 5.4 8.5 5.8 2.7 2.9 4.5 8.8 4.3 3.7 6.8 4.9 5.7 3.9 0.8 1.0 1.6 1.6 1.1 2.5 1.9 1.6 2.0 1.2 1.3 2.2 1.6 0.1 4.4 0.8 1.5 1.9 1.1 3.0 3.3 4.8 4.2 3.1 3.0 2.8 3.1 2.8 2.7 2.8 3.6 23.2 3.2 11.3 0.0 8.9 0.0 0.0 0.0 0.0 0.0 20.5 22.4 0.0 0.0 2.5 11.0 0.0 29.1 13.4 0.0 66.5 20.0 0.0 11.4 11.8 7.5 0.0 0.0 0.0 20.4 29.8 10.4 0.0 10.5 2.5 17.8 0.0 0.0 18.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 11.4 0.0 0.0 0.0 0.0 19.8 0.0 0.0 2.8 0.0 0.0 30.5 3.6 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.0 17.1 7.1 14.7 0.0 0.0 EFCAB7 "KIAA1799, RP4-534K7.1" ENSG00000203965 "EF-hand calcium binding domain 7" A8K855 1 63523372-63572693 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 55.3;Excitatory neurons: 58.9;Inhibitory neurons: 47.7;Oligodendrocyte precursor cells: 41.7;Spermatocytes: 73.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 10.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029611, HPA029612, HPA029613" Enhanced Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Plasma membrane,Cytosol" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Nucleoli, Nucleoli rim" "Plasma membrane, Cytosol" "HPA029611: AB_10599972, HPA029612: AB_10600533, HPA029613: AB_10601004" "unprognostic (8.81e-2)" "unprognostic (5.24e-2)" "unprognostic (5.13e-2)" "unprognostic (1.64e-1)" "prognostic favorable (3.65e-4)" "unprognostic (1.70e-2)" "unprognostic (6.53e-4)" "unprognostic (2.99e-1)" "unprognostic (5.81e-3)" "unprognostic (1.69e-1)" "unprognostic (6.28e-2)" "unprognostic (1.66e-1)" "unprognostic (3.78e-2)" "unprognostic (2.18e-1)" "unprognostic (6.97e-2)" "unprognostic (9.90e-2)" "unprognostic (2.73e-1)" 2.7 5.3 7.3 2.2 7.6 2.0 6.0 8.9 10.3 5.8 10.1 3.4 2.0 6.1 6.2 2.9 8.1 4.6 6.5 7.4 9.3 5.6 1.7 4.0 3.6 6.8 7.2 8.0 2.9 10.4 5.9 3.2 7.0 5.4 3.0 8.9 3.1 5.0 6.7 3.1 2.1 4.7 6.5 2.7 3.2 14.6 8.2 7.3 5.9 3.9 3.3 3.7 2.8 8.3 6.5 5.7 7.1 4.5 7.5 11.0 3.6 4.1 4.6 7.2 8.8 1.7 5.0 4.4 9.6 2.5 14.5 6.0 6.1 4.1 8.5 8.6 4.3 3.6 10.4 3.9 4.6 5.1 3.2 6.1 9.9 8.6 5.6 11.4 6.1 8.2 4.8 7.3 4.7 1.5 9.9 3.5 3.1 4.6 5.6 6.2 10.7 4.6 11.1 3.6 15.2 5.8 8.1 4.5 10.5 9.6 4.5 3.8 1.7 4.1 3.5 12.1 4.0 4.7 8.7 5.0 7.4 3.5 6.0 10.1 0.4 0.1 1.2 0.3 1.6 1.8 1.4 1.4 0.8 1.9 1.4 1.3 0.0 1.3 2.6 1.0 1.6 0.6 7.3 7.6 8.9 10.3 7.4 9.3 6.8 7.2 7.0 6.5 8.2 8.3 3.1 12.8 4.1 23.2 6.0 3.1 5.6 7.0 5.7 7.7 2.6 3.9 7.8 2.8 5.6 5.5 4.2 3.7 2.1 0.6 7.9 3.8 55.3 19.9 8.0 3.2 1.8 1.3 58.9 0.7 2.0 5.6 3.6 3.4 2.5 7.9 2.2 1.2 2.6 0.0 47.7 1.3 8.2 2.5 1.6 8.8 10.8 1.8 1.8 14.0 1.9 5.2 2.1 41.7 21.9 1.4 0.3 13.5 6.0 1.4 0.5 5.5 27.5 11.3 26.3 11.8 5.3 73.4 22.7 3.8 2.3 1.2 3.4 5.8 2.1 1.6 ENSA "ARPP-19e, MGC4319, MGC78563, MGC8394" ENSG00000143420 "Endosulfine alpha" O43768 1 150600851-150629612 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 11 "U-698: 8664.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051294 Uncertain Approved Nucleoplasm,Nucleoli,Microtubules,Cytosol NA NA 700000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 3: Monocytes - Immune response regulation" "Nucleoplasm, Nucleoli" "Microtubules, Cytosol" "HPA051294: AB_2681425" "unprognostic (6.27e-2)" "prognostic favorable (8.24e-4)" "unprognostic (1.06e-1)" "unprognostic (2.21e-2)" "unprognostic (2.58e-1)" "unprognostic (8.24e-2)" "unprognostic (1.94e-3)" "unprognostic (1.82e-1)" "unprognostic (2.02e-1)" "unprognostic (1.44e-3)" "unprognostic (1.21e-1)" "unprognostic (5.40e-2)" "unprognostic (2.21e-3)" "unprognostic (1.26e-1)" "unprognostic (2.75e-1)" "unprognostic (7.64e-2)" "unprognostic (8.07e-3)" 140.5 106.6 151.2 115.1 156.7 219.8 154.9 133.6 188.2 145.2 132.6 135.9 133.6 117.8 183.3 288.0 100.5 94.9 120.2 161.6 144.1 118.8 148.8 124.0 128.4 137.2 135.6 102.4 108.5 173.0 92.0 103.7 134.2 97.7 123.9 121.8 122.9 94.6 301.0 241.3 132.7 105.8 136.9 99.7 124.1 45.2 147.4 157.8 134.4 212.3 146.7 147.0 165.6 157.0 287.1 170.8 236.9 206.9 149.7 126.8 220.7 141.0 148.4 199.9 171.7 207.3 216.6 288.9 196.8 122.1 125.1 238.3 198.5 325.4 160.1 415.1 277.4 434.3 239.6 158.2 108.3 372.1 462.6 100.5 202.0 214.1 293.6 118.8 206.2 224.8 321.7 551.8 140.9 775.5 302.3 272.6 431.2 386.2 211.1 298.6 199.9 328.0 299.2 306.0 303.8 193.3 201.6 385.6 222.1 200.8 533.9 442.9 208.2 143.9 261.9 171.8 340.3 309.4 441.4 8664.2 197.1 357.6 191.8 67.3 54.4 94.3 55.6 62.9 52.2 64.3 46.3 57.5 70.7 55.3 37.7 56.0 53.0 68.8 64.3 58.3 58.2 75.1 151.2 156.7 133.6 188.2 161.6 144.1 137.2 135.6 134.2 136.9 147.4 157.0 103.1 41.7 166.1 20.9 132.9 190.3 225.1 303.9 124.7 59.7 152.7 117.1 102.6 98.7 172.9 82.8 45.9 286.5 148.9 170.7 254.3 160.3 9.7 109.1 68.5 114.2 130.8 178.2 44.7 152.4 184.2 85.9 71.9 93.7 224.3 51.1 80.3 86.9 203.3 67.3 29.3 169.1 211.6 101.1 171.4 17.7 86.0 123.3 103.2 19.7 409.7 83.6 184.4 21.6 19.3 91.5 146.8 104.2 135.6 128.0 187.2 186.0 128.8 50.0 72.3 85.5 94.4 27.6 25.0 269.7 286.8 382.8 140.4 87.9 163.9 253.7 EPHA3 "ETK, ETK1, HEK, HEK4, TYRO4" ENSG00000044524 "EPH receptor A3" P29320 3 89107621-89482134 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 31.5" "Group enriched" "Detected in some" 4 "Excitatory neurons: 70.6;Inhibitory neurons: 106.6;Microglial cells: 103.0;Oligodendrocytes: 48.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "AF22: 197.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB010462, HPA069390" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear membrane, Plasma membrane, Cytosol" "Nucleoplasm, Actin filaments" "CAB010462: AB_2099218, HPA069390: " "unprognostic (1.48e-3)" "unprognostic (2.30e-2)" "unprognostic (4.95e-2)" "unprognostic (1.90e-1)" "unprognostic (2.96e-2)" "unprognostic (1.47e-2)" "unprognostic (2.03e-1)" "unprognostic (9.10e-3)" "unprognostic (1.24e-3)" "unprognostic (7.43e-2)" "unprognostic (1.83e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (3.28e-7)" "unprognostic (3.63e-2)" "unprognostic (1.88e-2)" "unprognostic (4.05e-2)" "unprognostic (1.20e-2)" 5.4 1.0 2.1 1.8 1.3 0.0 2.3 0.2 3.8 12.3 0.1 3.8 2.3 5.5 0.2 3.2 1.3 18.8 8.2 2.2 0.7 1.3 4.9 2.4 3.6 3.3 0.9 4.1 2.1 1.0 0.9 20.1 4.0 31.5 6.2 8.0 2.2 7.1 0.8 0.7 2.4 7.9 0.8 0.9 2.5 1.0 1.7 1.0 11.0 6.3 3.2 14.3 6.4 2.2 0.0 0.0 197.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 11.2 0.2 0.7 0.0 2.4 0.0 0.0 11.8 0.0 0.0 1.7 2.0 0.0 3.9 0.0 0.0 0.6 0.0 2.5 0.1 0.3 0.0 2.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.1 0.0 0.5 0.1 0.1 36.1 0.1 0.0 0.0 1.7 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 1.3 0.2 3.8 2.2 0.7 3.3 0.9 4.0 0.8 1.7 2.2 2.2 0.0 0.0 5.5 0.0 0.5 0.3 0.0 0.6 6.4 0.0 0.1 2.4 0.0 0.0 0.0 2.1 0.2 0.0 0.0 0.0 0.0 1.8 0.0 0.5 1.8 0.0 0.0 70.6 0.0 0.1 18.1 0.5 0.0 0.0 0.0 1.1 0.0 0.1 20.2 106.6 0.0 0.0 0.0 0.7 1.6 2.1 0.1 0.0 103.0 0.0 4.7 0.0 2.5 48.0 0.0 0.0 8.2 0.0 0.1 0.0 0.0 0.0 18.7 6.6 0.7 19.2 0.1 0.0 0.3 0.3 0.5 0.2 1.3 0.0 0.1 EPN1 ENSG00000063245 "Epsin 1" Q9Y6I3 19 55675226-55709858 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 387.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEK 293: 263.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009729, HPA061136, HPA071503" Approved Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" No No "Cluster 8: Neutrophils - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 45: Enterocytes - Digestion" "Plasma membrane, Cytosol" "Nucleoplasm, Vesicles" "CAB009729: AB_2277865, HPA061136: AB_2684436, HPA071503: " "unprognostic (6.93e-2)" "unprognostic (2.47e-1)" "unprognostic (5.30e-2)" "unprognostic (1.32e-1)" "unprognostic (7.94e-2)" "unprognostic (8.76e-2)" "unprognostic (1.23e-2)" "unprognostic (7.23e-3)" "unprognostic (1.18e-1)" "unprognostic (1.28e-1)" "unprognostic (6.16e-2)" "unprognostic (4.63e-2)" "unprognostic (1.05e-2)" "unprognostic (3.86e-3)" "unprognostic (1.57e-1)" "unprognostic (2.78e-3)" "unprognostic (7.92e-3)" 57.1 75.3 63.1 27.3 61.2 22.1 53.0 30.3 82.2 51.1 14.8 73.1 88.7 47.8 9.2 80.5 48.7 14.3 148.6 65.2 31.5 85.2 137.1 50.5 19.3 37.8 38.5 76.2 104.3 22.3 51.1 17.4 31.1 64.8 16.2 8.9 50.9 20.0 156.1 71.0 80.4 11.0 27.9 72.8 152.6 80.8 40.0 11.6 49.0 35.3 11.2 50.1 54.5 47.1 95.5 128.8 31.5 64.8 35.6 33.8 64.6 69.3 39.0 48.2 48.0 54.1 58.7 58.1 46.1 55.6 42.5 71.5 27.7 52.9 17.4 20.4 263.2 42.8 67.4 65.3 48.9 27.8 39.3 43.9 45.6 41.7 30.1 34.7 46.4 40.7 64.7 48.0 32.2 53.6 44.4 45.2 72.3 71.4 179.6 29.5 42.8 103.2 36.8 55.3 45.2 109.9 64.1 68.8 48.0 21.7 51.6 95.7 78.4 133.0 63.8 48.4 101.3 52.2 50.9 41.7 97.9 55.0 67.5 1.4 1.8 2.3 0.6 2.2 0.4 1.0 0.6 0.6 1.1 0.8 0.6 0.6 2.1 0.3 3.6 1.7 0.9 1.5 63.1 61.2 30.3 82.2 65.2 31.5 37.8 38.5 31.1 27.9 40.0 47.1 62.6 3.2 20.4 9.8 44.2 31.4 29.0 25.9 44.3 33.3 32.7 25.8 15.5 55.8 17.9 44.1 66.7 46.1 28.1 227.7 119.3 57.1 63.2 39.5 37.5 46.1 45.0 35.3 7.8 88.5 80.8 37.2 145.2 45.9 10.8 87.0 83.9 106.1 62.9 28.6 7.8 115.6 22.4 136.5 21.4 169.4 47.5 55.4 23.2 6.5 40.8 33.6 28.8 4.5 8.9 106.5 167.7 53.0 57.7 37.6 387.2 81.8 20.9 41.3 13.1 41.2 34.6 50.2 62.7 46.6 27.4 52.3 26.3 48.2 132.5 39.2 ERVFRD-1 "envFRD, ERVFRDE1, HERV-FRD, HERV-W/FRD, syncytin-2" ENSG00000244476 "Endogenous retrovirus group FRD member 1, envelope" P60508 6 11102489-11111725 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "placenta: 37.0" "Cell type enriched" "Detected in some" 56 "Syncytiotrophoblasts: 575.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SuSa: 38.8" HPA011812 Uncertain "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 12: NES - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane, Actin filaments" "Nucleoplasm, Cytosol" "HPA011812: AB_1857702" "unprognostic (1.99e-1)" "unprognostic (3.29e-4)" "unprognostic (4.75e-2)" "unprognostic (1.80e-1)" "unprognostic (1.34e-1)" "unprognostic (2.19e-3)" "unprognostic (3.35e-1)" "unprognostic (6.44e-2)" "unprognostic (1.24e-1)" "unprognostic (1.99e-1)" "unprognostic (1.30e-2)" "unprognostic (2.78e-3)" "unprognostic (5.80e-4)" "unprognostic (3.40e-2)" "unprognostic (1.82e-1)" "unprognostic (1.95e-2)" "unprognostic (1.37e-2)" 0.3 0.4 0.6 0.1 0.4 0.2 0.4 1.8 0.6 0.4 0.0 0.3 0.5 0.3 1.0 0.3 0.2 0.4 0.1 0.6 0.7 0.5 0.2 0.6 0.0 0.6 0.4 0.0 0.0 7.5 0.0 37.0 0.5 0.3 0.2 0.2 0.2 0.2 0.0 0.5 0.5 0.2 0.1 0.0 0.3 0.1 0.6 0.4 0.0 0.4 0.0 0.5 0.2 0.6 0.0 0.1 0.0 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 38.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.4 1.8 0.6 0.6 0.7 0.6 0.4 0.5 0.1 0.6 0.6 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.6 0.0 0.6 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.1 0.3 0.0 0.0 10.1 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.1 0.0 0.0 0.0 575.5 0.4 0.5 0.0 0.0 ESRRA "ERR1, ERRa, ERRalpha, ESRL1, NR3B1" ENSG00000173153 "Estrogen related receptor alpha" P11474 11 64305497-64316743 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 195.3" "Cell type enhanced" "Detected in all" "Distal enterocytes: 159.2;Hepatocytes: 266.3;Proximal enterocytes: 199.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053785, HPA077297" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Microtubules,Cytokinetic bridge" Yes No "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Nucleoli fibrillar center, Microtubules" "Cytokinetic bridge" "HPA053785: AB_2682260, HPA077297: " "unprognostic (7.63e-2)" "unprognostic (1.51e-1)" "unprognostic (1.04e-1)" "unprognostic (1.28e-2)" "unprognostic (3.08e-1)" "unprognostic (7.24e-2)" "unprognostic (1.07e-1)" "unprognostic (2.97e-1)" "unprognostic (2.98e-1)" "unprognostic (3.52e-2)" "unprognostic (2.50e-2)" "unprognostic (1.03e-1)" "prognostic favorable (1.34e-7)" "unprognostic (3.43e-3)" "unprognostic (3.19e-2)" "unprognostic (2.38e-2)" "unprognostic (7.20e-2)" 27.3 35.5 25.5 15.8 29.8 16.3 23.6 36.4 31.4 17.5 33.6 67.6 81.8 15.5 4.7 62.7 14.6 10.2 154.9 23.5 31.6 70.3 91.5 30.9 11.0 30.9 31.7 8.1 56.3 23.9 15.9 15.4 29.8 26.4 22.9 5.1 48.5 12.6 195.3 35.9 65.4 7.1 26.6 32.0 52.4 8.4 37.5 8.4 28.3 88.8 12.4 31.0 28.8 23.7 25.9 40.2 9.8 23.6 13.0 12.7 54.2 25.0 11.9 9.2 9.0 37.4 30.3 34.9 45.1 12.8 23.7 66.0 16.9 33.0 3.5 23.0 21.0 22.9 51.7 30.1 18.0 39.3 55.3 17.4 49.8 20.7 27.0 12.8 12.8 18.1 37.9 18.7 15.3 57.9 19.4 55.9 27.9 30.4 74.4 20.4 19.7 79.6 31.1 52.4 20.6 26.2 12.8 81.2 83.8 5.5 25.8 38.2 28.9 16.6 20.4 47.4 25.6 28.6 25.5 23.6 26.9 38.2 13.4 0.2 2.9 4.8 2.7 5.4 2.6 1.7 2.3 1.9 2.7 2.3 2.3 3.3 5.3 1.8 5.1 2.1 3.6 1.7 25.5 29.8 36.4 31.4 23.5 31.6 30.9 31.7 29.8 26.6 37.5 23.7 20.8 9.6 22.7 21.2 14.7 18.6 41.0 29.7 18.8 28.8 30.9 24.3 9.2 100.1 21.3 20.2 33.3 103.8 20.9 159.2 54.8 51.3 3.4 18.7 17.4 15.3 37.8 19.4 13.6 80.2 61.3 12.4 39.8 20.3 7.6 9.3 35.0 266.3 33.6 33.7 16.6 82.5 28.5 82.7 11.7 1.1 6.5 22.2 17.8 11.2 28.8 20.1 27.8 9.0 6.4 81.1 103.1 12.0 8.2 42.8 199.7 82.2 19.8 20.4 13.1 18.7 21.7 3.5 7.1 26.3 18.5 134.2 14.5 22.2 113.7 65.0 EVC2 LBN ENSG00000173040 "EvC ciliary complex subunit 2" Q86UK5 4 5542772-5709548 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Ciliopathy, Disease variant, Dwarfism, Ectodermal dysplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 17.6;Basal squamous epithelial cells: 12.0;Fibroblasts: 8.9;Leydig cells: 11.5;Skeletal myocytes: 14.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 9.7;HHSteC: 13.0;hTERT-HME1: 10.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040910, HPA048122" Uncertain Approved "Nucleoplasm,Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "Microtubules, Cytokinetic bridge" "Nucleoplasm, Cytosol" "HPA040910: AB_2677195, HPA048122: AB_2680272" "unprognostic (6.56e-2)" "unprognostic (6.74e-2)" "unprognostic (5.10e-2)" "unprognostic (2.25e-1)" "unprognostic (8.23e-3)" "unprognostic (2.80e-1)" "unprognostic (2.05e-2)" "unprognostic (1.22e-2)" "unprognostic (1.71e-1)" "unprognostic (1.28e-1)" "unprognostic (8.57e-2)" "unprognostic (9.37e-2)" "prognostic favorable (1.58e-4)" "unprognostic (2.51e-2)" "unprognostic (3.14e-1)" "unprognostic (5.61e-2)" "unprognostic (6.29e-5)" 4.8 0.7 1.3 1.5 1.4 0.1 3.6 1.2 1.1 6.0 2.3 3.7 0.6 4.7 1.7 2.2 4.7 2.7 3.1 1.3 1.4 2.6 0.7 2.1 1.9 1.6 1.5 7.8 1.7 3.1 1.1 1.3 1.2 3.2 0.6 0.3 2.8 2.0 1.1 3.8 2.0 2.3 1.4 1.0 2.1 1.6 1.5 1.0 3.8 1.9 1.7 4.1 4.4 1.3 0.0 2.7 0.0 6.6 8.4 9.3 0.0 4.1 9.7 3.6 6.0 0.0 0.0 5.2 0.0 3.3 2.0 2.8 0.0 1.7 3.4 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 5.9 4.6 4.6 10.6 0.0 3.9 0.0 0.0 0.2 5.3 0.0 0.0 0.0 3.9 0.0 0.0 8.6 8.2 0.0 0.4 0.0 0.4 0.6 0.0 0.0 0.0 1.6 0.0 0.5 6.7 0.0 0.0 2.4 0.0 4.1 4.7 1.2 2.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.3 1.4 1.2 1.1 1.3 1.4 1.6 1.5 1.2 1.4 1.5 1.3 0.6 0.0 0.5 17.6 0.8 2.2 4.9 2.3 12.0 0.0 0.9 2.2 1.0 1.5 1.3 0.0 0.0 8.3 1.7 0.0 0.0 1.9 2.2 0.7 5.6 1.2 0.0 0.4 0.3 0.5 0.3 8.9 0.5 1.7 2.5 4.7 1.4 0.1 0.5 0.0 0.3 0.0 0.0 0.3 1.2 0.9 11.5 0.8 0.0 6.5 0.0 1.9 1.0 1.0 0.3 0.6 0.0 7.9 1.7 2.8 0.0 0.9 1.0 0.1 0.0 14.7 3.2 1.8 2.1 4.4 0.9 1.4 2.8 3.4 0.0 1.4 EXOC3L2 "FLJ36147, XTP7" ENSG00000283632 "Exocyst complex component 3 like 2" 19 45212370-45245407 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "kidney: 19.0;thyroid gland: 17.9" "Group enriched" "Detected in some" 4 "Adipocytes: 15.3;Endothelial cells: 17.7;Hepatic stellate cells: 51.4;Theca cells: 21.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HEL: 19.1;K-562: 16.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041595, HPA061110" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "Nucleoplasm, Golgi apparatus, Cytosol" "HPA041595: AB_10794521, HPA061110: AB_2684431" 4.3 8.3 0.3 2.1 0.6 1.6 2.9 0.5 0.4 4.0 1.6 2.7 2.4 4.9 0.4 1.9 2.8 2.3 2.3 0.4 0.3 19.0 2.7 2.7 1.1 0.7 0.5 0.9 2.7 3.3 5.0 0.4 0.5 5.2 0.7 0.1 1.8 2.2 0.9 2.1 3.2 1.9 0.3 8.3 2.9 3.3 0.4 0.4 17.9 0.3 0.5 3.2 2.4 0.7 0.1 0.3 2.5 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.3 0.1 2.2 0.0 0.2 0.8 0.0 0.0 0.0 0.1 0.1 19.1 0.6 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 16.6 0.2 0.0 0.2 0.0 0.0 0.1 0.1 0.5 1.1 0.0 0.1 0.0 0.2 0.3 0.0 0.1 0.1 0.1 1.0 0.1 0.3 0.6 0.8 1.5 0.2 0.1 0.2 0.1 0.0 0.1 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.5 0.4 0.4 0.3 0.7 0.5 0.5 0.3 0.4 0.7 15.3 0.0 1.3 0.7 0.7 0.4 0.3 0.0 0.0 0.7 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.2 17.7 0.0 0.0 1.5 0.0 0.0 0.5 0.0 0.2 0.0 0.4 51.4 0.3 0.0 0.0 1.1 0.6 0.0 1.6 0.0 0.0 1.8 2.8 0.0 0.0 0.1 0.2 2.1 0.5 0.7 0.0 0.0 1.9 0.1 0.2 0.1 0.1 0.0 0.2 0.0 0.3 0.6 0.4 6.2 0.2 0.9 0.0 0.1 21.2 0.0 0.3 EXOC4 "KIAA1699, MGC27170, SEC8, SEC8L1, Sec8p" ENSG00000131558 "Exocyst complex component 4" Q96A65 7 133253073-134066589 "Plasma proteins, Predicted intracellular proteins, Transporters" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 238.6;Excitatory neurons: 334.2;Inhibitory neurons: 306.8;Microglial cells: 341.0;Oligodendrocyte precursor cells: 395.6;Oligodendrocytes: 345.9;Rod photoreceptor cells: 231.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031443, HPA031444" Approved Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA NA 10000 "Cluster 27: Non-specific - Gene expression" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoli, Nucleoli rim" "Nucleoplasm, Cytosol" "HPA031443: AB_10602496, HPA031444: AB_2673886" "unprognostic (1.70e-1)" "unprognostic (1.62e-2)" "unprognostic (2.05e-1)" "unprognostic (5.09e-2)" "unprognostic (1.03e-1)" "unprognostic (4.06e-3)" "unprognostic (8.63e-2)" "unprognostic (2.33e-1)" "unprognostic (4.40e-1)" "unprognostic (2.04e-1)" "prognostic unfavorable (6.19e-4)" "unprognostic (9.78e-3)" "prognostic favorable (6.85e-5)" "unprognostic (5.91e-2)" "unprognostic (2.18e-1)" "unprognostic (3.37e-1)" "unprognostic (3.35e-2)" 20.7 21.1 18.7 13.8 20.2 13.8 21.4 19.3 20.3 22.6 24.3 19.7 13.1 21.5 13.6 24.4 27.3 17.8 15.3 20.9 19.4 17.7 17.8 17.7 16.4 18.4 20.3 30.6 27.3 27.3 16.9 19.6 19.9 18.3 21.5 53.1 16.3 20.5 68.4 25.4 13.5 23.9 18.8 21.0 17.3 18.7 19.1 28.1 26.4 38.5 20.3 21.1 18.6 20.8 40.1 32.2 43.3 43.3 49.7 51.6 15.0 28.6 47.2 25.4 33.2 18.8 54.7 29.8 20.1 54.1 36.9 24.7 23.7 38.8 41.8 45.6 28.2 24.0 31.5 19.9 54.7 32.0 25.1 50.4 47.6 36.3 66.5 55.7 43.5 38.6 35.1 28.8 47.7 26.1 58.5 35.2 32.8 47.5 29.8 25.7 38.7 54.2 40.7 35.2 33.9 53.2 43.0 39.1 46.3 48.9 25.8 29.3 47.9 28.1 14.6 30.0 31.5 45.0 29.4 28.1 82.9 36.4 43.8 10.3 12.0 7.2 11.2 12.9 10.0 8.3 11.6 11.9 16.3 8.1 9.4 9.6 4.0 19.6 11.4 7.2 12.9 11.2 18.7 20.2 19.3 20.3 20.9 19.4 18.4 20.3 19.9 18.8 19.1 20.8 22.9 22.4 22.3 238.6 27.3 18.9 16.3 16.6 25.6 39.9 16.8 15.4 30.9 11.5 18.0 14.7 93.8 17.5 26.7 21.5 3.9 15.0 29.6 27.0 21.2 23.0 17.4 18.7 334.2 18.2 16.6 21.2 34.1 21.0 8.2 32.4 23.2 15.9 18.1 50.5 306.8 21.0 26.4 27.3 14.5 27.6 17.4 20.4 14.2 341.0 23.9 20.4 23.7 395.6 345.9 15.4 17.4 18.8 27.7 13.2 16.3 16.9 29.8 231.5 13.1 26.0 15.3 20.5 13.1 28.2 17.0 11.2 26.2 26.4 21.9 20.1 EXOSC10 "p2, p3, p4, PM-Scl, PM/Scl-100, PMSCL2, RRP6, Rrp6p" ENSG00000171824 "Exosome component 10" Q01780 1 11066618-11099869 "Predicted intracellular proteins" "Nonsense-mediated mRNA decay, rRNA processing" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028470, HPA028484, CAB037141" Supported Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" No No "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nucleoli, Nucleoli rim" "Nucleoplasm, Cytosol" "CAB037141: AB_532315, HPA028470: AB_10599180, HPA028484: AB_10611250" "unprognostic (1.23e-2)" "unprognostic (3.46e-2)" "unprognostic (1.85e-2)" "unprognostic (1.62e-1)" "unprognostic (6.88e-2)" "unprognostic (6.37e-2)" "prognostic unfavorable (2.49e-6)" "unprognostic (3.36e-1)" "unprognostic (4.66e-2)" "unprognostic (2.52e-1)" "unprognostic (5.49e-2)" "unprognostic (2.52e-2)" "unprognostic (7.68e-3)" "unprognostic (3.43e-1)" "unprognostic (9.03e-2)" "prognostic favorable (5.27e-4)" "unprognostic (1.33e-1)" 31.8 21.4 18.3 25.9 18.4 39.4 30.8 23.1 22.2 32.5 14.7 27.6 20.7 28.7 23.9 27.3 26.4 19.2 20.3 17.7 15.9 21.8 20.0 24.3 31.1 17.2 15.2 35.8 24.0 25.2 26.1 26.1 16.6 25.3 27.6 35.4 25.4 21.0 33.3 37.0 26.1 27.5 13.7 27.4 26.1 23.4 17.9 32.7 23.3 22.6 34.2 24.6 28.4 19.1 66.4 41.5 84.9 33.0 44.3 48.7 48.5 63.8 46.8 109.8 99.1 61.6 94.1 66.3 40.3 61.0 48.8 64.2 95.0 71.2 100.1 74.9 95.0 96.5 80.5 63.2 43.4 79.5 73.7 38.4 60.2 108.1 63.1 40.9 69.4 58.0 103.2 59.3 61.4 37.4 78.5 73.1 56.5 50.3 49.1 79.8 72.2 58.1 64.8 33.3 54.5 53.3 68.8 58.9 77.0 59.4 51.5 72.1 63.6 58.2 60.4 53.0 76.2 35.7 60.0 130.0 59.4 116.2 71.5 57.7 32.0 26.6 36.2 41.5 43.0 36.4 37.7 36.7 37.9 36.5 31.9 35.4 6.2 49.3 51.2 19.3 39.4 43.3 18.3 18.4 23.1 22.2 17.7 15.9 17.2 15.2 16.6 13.7 17.9 19.1 18.4 28.9 18.3 17.0 26.1 13.3 14.3 19.8 26.2 14.9 11.0 23.6 6.4 12.8 29.2 5.5 47.9 26.5 18.8 16.4 9.8 25.0 16.4 14.3 21.0 20.1 9.0 28.0 20.3 31.9 34.3 17.2 31.1 19.2 20.2 26.2 13.9 11.1 24.7 21.9 24.3 16.5 22.4 15.1 14.1 7.1 29.5 18.7 12.4 9.4 24.0 6.1 28.8 30.2 15.2 30.2 9.4 23.0 26.8 8.5 12.7 8.8 27.3 34.8 13.1 18.4 17.6 21.9 20.8 28.7 13.4 22.7 21.2 19.7 20.1 10.0 FAM161B "C14orf44, FLJ31697" ENSG00000156050 "FAM161 centrosomal protein B" Q96MY7 14 73931501-73950414 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Early spermatids: 62.9;Late spermatids: 142.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019125 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 21: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA019125: AB_1845570" "unprognostic (1.50e-1)" "unprognostic (9.03e-2)" "unprognostic (6.35e-2)" "unprognostic (1.99e-1)" "unprognostic (9.51e-2)" "unprognostic (1.79e-2)" "unprognostic (1.76e-3)" "unprognostic (5.54e-2)" "unprognostic (1.81e-1)" "unprognostic (1.57e-1)" "unprognostic (7.83e-2)" "unprognostic (1.53e-1)" "prognostic favorable (6.78e-4)" "unprognostic (1.26e-1)" "unprognostic (1.37e-1)" "unprognostic (7.35e-2)" "unprognostic (1.60e-1)" 2.7 8.7 6.6 1.7 6.6 1.2 4.8 5.8 8.2 5.3 3.4 3.9 3.3 5.2 4.3 4.1 5.5 2.7 5.4 6.4 5.9 7.2 5.1 2.8 1.8 6.8 5.7 12.8 2.2 4.3 7.6 2.4 7.1 6.0 2.7 10.1 2.8 5.2 7.9 2.1 3.3 3.4 5.5 3.1 3.3 18.8 6.1 1.9 4.2 4.8 1.8 5.5 3.8 6.6 2.1 1.6 2.2 3.4 4.7 3.5 2.0 3.6 2.8 6.0 5.8 1.5 2.6 3.3 2.3 4.2 2.5 3.9 0.9 1.7 4.1 9.2 1.8 1.6 1.6 1.7 4.0 1.1 2.3 2.6 3.4 6.1 2.2 4.4 2.7 3.4 1.0 1.6 4.3 3.3 3.1 4.2 0.5 1.4 3.5 2.1 2.9 1.3 3.1 3.1 2.7 2.5 5.1 2.3 3.1 1.6 8.1 1.5 2.9 12.4 5.6 3.1 2.2 3.3 2.2 2.1 6.3 1.9 2.2 3.2 1.3 1.9 1.1 0.3 1.3 0.7 1.2 1.7 0.2 0.9 0.6 0.4 0.4 1.3 0.4 0.3 0.7 0.9 6.6 6.6 5.8 8.2 6.4 5.9 6.8 5.7 7.1 5.5 6.1 6.6 3.5 3.2 4.8 4.9 3.0 0.6 2.1 1.0 3.4 8.9 3.7 3.8 3.4 0.0 3.2 1.8 4.2 1.5 1.9 3.5 0.0 1.0 62.9 5.9 3.9 2.2 0.0 1.7 7.3 1.6 1.1 4.6 7.1 4.5 0.0 5.0 2.5 0.7 2.9 3.3 8.6 4.1 2.0 1.2 0.7 142.7 3.4 1.4 1.8 2.8 2.2 8.0 6.2 5.5 2.9 1.2 0.8 9.4 1.4 0.8 4.3 4.2 9.4 16.7 6.6 5.2 4.2 11.0 6.1 0.6 0.9 2.2 3.3 9.6 1.4 0.9 FANCD2 "FA-D2, FACD, FAD, FANCD" ENSG00000144554 "FA complementation group D2" Q9BXW9 3 10026414-10101932 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 25.2;Spermatocytes: 62.5;Spermatogonia: 30.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 120.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB016117, HPA063742" Approved Supported "Nucleoplasm,Nucleoli,Nuclear bodies,Cytosol" No No "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nucleoli, Nuclear bodies, Cytosol" "CAB016117: AB_2278211, HPA063742: AB_2685110" "unprognostic (3.25e-2)" "unprognostic (1.09e-1)" "unprognostic (6.21e-2)" "unprognostic (1.12e-2)" "unprognostic (2.92e-1)" "unprognostic (3.36e-2)" "unprognostic (1.08e-5)" "unprognostic (2.96e-2)" "unprognostic (1.59e-3)" "prognostic unfavorable (5.00e-5)" "unprognostic (1.23e-2)" "unprognostic (9.14e-2)" "unprognostic (4.41e-10)" "unprognostic (9.11e-3)" "unprognostic (3.99e-1)" "unprognostic (7.76e-2)" "unprognostic (2.89e-2)" 1.1 0.7 2.7 7.7 2.1 17.8 3.4 1.6 5.3 1.5 1.1 4.0 3.2 2.0 0.7 2.5 2.6 2.0 0.5 3.4 1.6 0.9 1.1 1.9 12.2 3.9 1.4 3.6 0.8 0.8 0.5 4.7 3.0 1.9 6.4 3.1 4.9 1.0 4.8 4.5 4.0 2.0 2.4 6.4 3.5 11.8 2.3 9.8 1.9 0.4 13.0 2.3 1.3 5.1 24.1 25.4 46.5 13.2 2.4 3.5 120.7 22.0 9.8 31.3 25.4 18.8 23.0 46.7 9.8 7.0 25.1 20.2 48.8 16.7 31.0 22.6 33.0 63.6 39.6 17.9 0.4 48.1 37.9 1.2 2.6 34.1 18.4 4.2 18.4 39.3 39.6 51.6 23.1 27.2 40.6 17.9 56.1 18.1 17.6 43.4 37.7 32.5 10.3 26.7 13.0 25.3 26.4 20.1 8.3 33.5 31.0 29.4 10.6 24.6 28.4 15.1 31.5 21.7 46.4 77.2 14.1 47.7 43.2 2.7 0.6 1.9 0.6 0.5 0.6 2.4 0.9 0.5 0.4 3.2 1.1 0.9 1.5 1.0 1.4 1.8 1.5 0.5 2.7 2.1 1.6 5.3 3.4 1.6 3.9 1.4 3.0 2.4 2.3 5.1 0.7 0.0 0.5 0.7 12.5 4.6 3.5 2.9 2.8 3.1 4.5 2.7 2.0 1.5 1.9 1.8 10.4 12.7 5.6 3.1 0.0 1.9 5.9 2.6 1.5 2.1 1.2 25.2 3.0 3.5 15.2 2.6 2.0 3.4 1.3 11.8 3.3 1.5 5.7 0.0 2.6 3.2 6.1 3.8 7.0 8.0 2.1 3.7 3.6 1.9 4.9 0.6 1.0 1.5 2.4 1.8 3.6 1.5 8.1 2.2 0.5 0.7 2.0 5.6 19.7 2.6 2.1 62.5 30.2 4.1 2.7 7.0 5.2 1.6 7.6 3.1 FBXO16 FBX16 ENSG00000214050 "F-box protein 16" Q8IX29 8 28348287-28490278 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 18.4;pituitary gland: 17.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 35.5;Excitatory neurons: 44.4;Inhibitory neurons: 43.6;Rod photoreceptor cells: 48.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 10 "plasmacytoid DC: 9.6" "Lineage enriched" "Detected in single" 10 "dendritic cells: 9.6" "Cell line enhanced" "Detected in many" "AF22: 20.3;Karpas-707: 22.4" "Low region specificity" "Detected in all" "HPA058676, HPA076472" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Vesicles, Plasma membrane, Cytosol" "HPA058676: AB_2683795, HPA076472: " "unprognostic (3.44e-1)" "unprognostic (1.44e-1)" "unprognostic (3.37e-3)" "unprognostic (5.56e-3)" "unprognostic (1.87e-1)" "unprognostic (1.40e-2)" "unprognostic (2.55e-3)" "unprognostic (4.95e-3)" "unprognostic (6.49e-2)" "prognostic favorable (6.70e-5)" "unprognostic (3.41e-3)" "unprognostic (4.90e-2)" "unprognostic (7.15e-2)" "unprognostic (1.71e-2)" "unprognostic (4.85e-2)" "unprognostic (2.72e-2)" "unprognostic (2.07e-1)" 0.5 1.8 3.9 0.9 5.0 2.2 2.6 6.8 7.0 4.1 2.9 1.6 2.0 1.1 18.4 0.7 4.4 1.4 1.4 4.6 3.9 3.2 6.0 1.5 1.4 1.1 1.7 0.7 4.7 7.1 17.3 0.6 2.0 3.5 2.0 14.3 3.4 5.1 1.1 0.4 2.9 0.7 0.3 1.2 2.2 4.2 3.5 0.6 7.0 0.9 2.8 1.2 0.7 4.3 16.5 2.9 20.3 7.5 0.5 0.0 0.3 0.2 0.5 3.0 5.5 3.1 4.6 5.8 7.2 0.1 8.1 5.1 2.3 3.5 3.0 2.6 3.6 2.7 0.3 1.7 0.0 3.5 1.9 0.2 10.8 0.7 3.2 1.5 0.0 5.6 1.1 22.4 1.0 5.7 0.5 5.0 3.9 2.2 4.5 0.2 4.5 8.2 3.9 2.4 13.1 5.4 0.4 3.3 9.5 3.5 13.8 5.9 0.6 1.6 5.8 3.2 3.0 5.2 5.0 5.2 6.8 0.7 3.5 0.3 0.1 0.1 0.1 0.1 0.3 0.3 0.2 0.1 0.7 0.2 0.1 0.2 0.9 0.0 0.1 9.6 0.2 0.1 3.9 5.0 6.8 7.0 4.6 3.9 1.1 1.7 2.0 0.3 3.5 4.3 0.0 3.2 4.1 7.5 1.7 0.1 3.0 10.9 5.2 8.2 3.9 3.4 2.1 8.6 7.9 3.7 35.5 0.6 0.0 0.5 7.9 5.3 12.1 13.5 1.3 0.2 10.2 0.0 44.4 4.6 0.4 0.9 1.5 6.4 0.0 1.9 0.4 1.9 2.7 5.0 43.6 3.9 4.1 0.8 2.3 12.4 1.2 0.4 0.0 2.8 0.0 9.3 0.0 23.6 3.2 3.1 0.4 0.7 11.1 1.7 0.2 4.7 23.4 48.6 0.0 0.5 1.8 10.5 5.6 1.2 0.0 0.0 0.5 4.2 1.0 1.7 FBXO38 "Fbx38, FLJ13962, MOKA, SP329" ENSG00000145868 "F-box protein 38" Q6PIJ6 5 148383935-148442836 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034821, HPA041444" Approved Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge,Cytosol" Yes No "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Plasma membrane" "Cytokinetic bridge, Cytosol" "HPA034821: AB_10669897, HPA041444: AB_2677484" "unprognostic (7.72e-2)" "unprognostic (5.75e-3)" "unprognostic (1.95e-2)" "unprognostic (1.67e-1)" "unprognostic (2.21e-1)" "unprognostic (2.70e-2)" "unprognostic (7.06e-2)" "unprognostic (5.43e-3)" "unprognostic (1.45e-1)" "unprognostic (1.12e-1)" "unprognostic (2.03e-1)" "unprognostic (6.29e-2)" "unprognostic (2.21e-3)" "unprognostic (1.31e-3)" "unprognostic (1.83e-1)" "unprognostic (1.64e-1)" "unprognostic (4.70e-3)" 12.8 11.5 7.3 12.9 8.4 9.8 13.9 8.1 9.9 14.1 8.2 12.5 9.6 12.5 11.1 10.5 10.0 11.5 17.4 7.0 7.7 12.9 18.0 14.5 14.6 8.0 7.6 12.3 9.5 18.5 10.2 13.8 8.0 14.6 13.0 11.0 11.5 12.0 18.7 12.2 11.6 12.3 7.5 14.4 12.5 12.4 7.8 20.2 12.2 16.8 15.6 13.8 11.2 9.9 12.6 13.2 20.1 14.7 22.1 24.6 10.4 16.1 30.7 22.4 30.5 19.6 15.1 18.2 15.5 26.2 23.6 17.2 21.2 20.3 26.8 20.1 13.6 10.8 19.0 13.3 21.9 29.6 17.0 24.0 17.1 21.6 21.1 24.0 30.7 16.6 12.2 19.1 22.3 5.1 18.8 13.8 9.4 13.9 19.8 16.6 29.3 18.4 21.7 14.5 17.9 17.3 21.4 14.2 21.2 17.1 15.0 21.2 20.2 20.4 7.3 10.8 18.2 23.3 25.1 15.3 20.3 16.6 15.8 15.1 6.1 9.1 5.0 8.0 5.5 4.9 4.7 5.0 7.5 3.8 4.8 6.2 11.2 7.7 15.2 3.7 7.4 4.9 7.3 8.4 8.1 9.9 7.0 7.7 8.0 7.6 8.0 7.5 7.8 9.9 10.6 16.0 45.7 25.1 13.8 3.3 5.5 7.4 7.4 10.3 8.5 6.7 18.7 11.5 10.6 11.0 10.4 7.5 13.4 11.3 5.9 8.8 11.2 8.9 9.9 10.8 9.6 7.2 40.2 6.7 6.8 11.8 14.8 10.4 15.8 9.6 11.4 16.9 12.6 13.5 37.4 10.1 6.1 24.9 6.4 2.9 9.0 17.8 3.6 38.4 12.3 5.9 12.3 33.2 44.4 9.9 8.9 18.4 11.0 8.6 9.3 9.3 16.4 9.0 0.0 6.9 7.8 20.6 8.6 9.2 3.8 12.3 12.1 11.2 9.0 8.7 FIGN ENSG00000182263 "Fidgetin, microtubule severing factor" Q5HY92 2 163593396-163736012 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 161.3;Inhibitory neurons: 82.9;Oligodendrocyte precursor cells: 309.6;Oligodendrocytes: 129.4;Sertoli cells: 72.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 34 "basophil: 3.3" "Lineage enriched" "Detected in single" 34 "granulocytes: 3.3" "Cell line enhanced" "Detected in many" "AF22: 18.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034987, HPA057919" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Plasma membrane, Cytosol" "Vesicles, Cell Junctions" "HPA034987: AB_10669681, HPA057919: " "unprognostic (3.93e-2)" "unprognostic (8.30e-3)" "unprognostic (1.48e-1)" "unprognostic (7.68e-5)" "unprognostic (3.45e-2)" "unprognostic (8.98e-4)" "unprognostic (5.23e-3)" "unprognostic (7.65e-3)" "unprognostic (2.33e-1)" "unprognostic (1.64e-1)" "unprognostic (2.07e-2)" "unprognostic (3.24e-2)" "unprognostic (3.85e-3)" "unprognostic (3.22e-2)" "unprognostic (2.69e-1)" "unprognostic (4.10e-2)" "unprognostic (3.78e-2)" 3.1 2.0 3.9 0.4 5.0 0.8 2.0 2.3 4.4 2.4 0.0 2.6 0.4 1.1 1.2 0.6 1.9 1.1 3.3 2.5 5.4 1.9 3.2 1.4 0.6 3.0 4.2 4.6 2.9 0.4 2.6 1.1 3.9 1.6 0.7 1.4 2.6 2.7 1.0 1.0 1.4 0.9 1.8 3.0 1.8 1.1 4.6 0.2 1.1 1.7 0.2 1.7 2.4 5.1 6.4 2.3 18.6 0.0 0.0 0.0 6.8 2.4 1.6 1.7 3.2 0.0 2.2 0.0 6.6 2.6 3.4 0.9 6.2 2.6 1.3 0.0 4.6 0.0 4.7 4.6 1.5 0.0 0.0 0.8 2.2 3.3 9.0 2.6 4.0 0.0 0.0 0.0 5.1 1.6 0.0 0.0 7.9 0.4 2.9 0.0 6.3 0.0 4.2 2.1 2.9 2.5 0.0 1.8 1.7 10.3 2.0 0.0 0.4 7.6 6.8 0.0 5.1 1.1 0.0 0.0 2.3 0.0 4.3 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 5.0 2.3 4.4 2.5 5.4 3.0 4.2 3.9 1.8 4.6 5.1 2.9 6.4 7.3 161.3 0.7 1.9 0.1 2.8 1.8 24.4 5.7 2.7 19.4 20.0 3.0 12.9 0.0 21.2 0.2 0.1 1.9 3.7 3.8 0.7 0.7 2.1 0.0 0.0 53.4 1.5 7.4 11.6 4.1 1.6 0.0 23.6 7.9 13.5 1.4 6.7 82.9 0.0 4.1 0.0 1.6 6.4 51.9 0.6 17.8 28.1 0.0 4.3 0.0 309.6 129.4 1.1 0.0 34.3 0.0 1.8 0.0 8.1 4.0 2.1 72.3 16.6 17.8 1.1 1.2 1.0 0.4 16.8 0.2 7.0 0.0 0.0 FNDC3A "bA203I16.5, FNDC3, KIAA0970" ENSG00000102531 "Fibronectin type III domain containing 3A" Q9Y2H6 13 48975912-49209779 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008927, HPA012555, HPA012825" Approved Approved "Nucleoplasm,Golgi apparatus,Centrosome,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Golgi apparatus, Centrosome" Cytosol "HPA008927: AB_1078899, HPA012555: , HPA012825: AB_1848985" "unprognostic (1.54e-1)" "unprognostic (1.34e-3)" "unprognostic (8.83e-2)" "unprognostic (1.04e-2)" "unprognostic (1.66e-1)" "unprognostic (1.11e-1)" "unprognostic (2.91e-2)" "unprognostic (5.71e-2)" "unprognostic (6.17e-2)" "unprognostic (3.16e-2)" "unprognostic (1.87e-2)" "unprognostic (4.03e-2)" "prognostic favorable (4.25e-4)" "unprognostic (8.93e-3)" "unprognostic (1.03e-1)" "unprognostic (9.60e-2)" "unprognostic (6.14e-2)" 17.8 39.9 15.2 18.7 18.6 17.0 26.3 12.7 16.4 35.2 13.6 23.3 27.5 32.1 38.8 13.1 26.5 26.8 14.0 15.3 39.4 29.7 66.9 21.6 16.7 16.7 19.6 35.4 43.1 27.7 30.8 44.1 17.4 22.1 24.0 21.9 36.8 33.9 10.1 11.4 23.8 26.0 15.5 22.6 28.8 30.4 31.9 21.3 51.2 13.1 18.9 25.6 14.1 17.9 11.6 13.1 47.1 12.4 58.3 73.0 9.2 53.3 70.8 50.2 36.3 17.9 27.7 8.8 9.7 40.5 21.8 12.4 28.4 18.1 72.6 22.1 21.9 14.3 36.9 33.2 35.3 13.4 2.3 37.7 24.8 44.7 51.4 47.1 52.6 11.9 18.0 21.0 55.4 4.7 13.3 26.7 23.2 25.0 11.0 12.6 18.8 16.4 42.4 21.2 17.8 29.4 20.1 17.8 38.8 29.8 9.6 26.0 41.7 26.1 17.9 24.3 38.3 25.4 14.4 8.1 19.6 16.9 27.4 1.9 3.0 1.9 2.5 2.0 3.6 3.3 2.9 2.2 1.9 2.2 3.7 3.3 4.5 2.1 4.0 4.0 2.6 1.7 15.2 18.6 12.7 16.4 15.3 39.4 16.7 19.6 17.4 15.5 31.9 17.9 46.7 54.5 49.0 88.2 36.2 18.4 37.4 17.5 44.3 52.0 33.4 25.5 27.1 27.1 28.9 36.8 37.5 13.2 36.4 21.6 13.7 30.6 45.9 42.1 74.3 42.4 43.5 17.9 159.5 36.2 38.2 58.0 57.6 56.4 31.6 38.8 32.9 74.2 25.4 35.3 170.8 37.4 18.3 31.8 24.4 13.1 33.8 45.5 37.4 112.4 27.0 52.7 24.7 177.9 178.2 25.5 29.0 39.5 165.9 44.2 37.8 48.0 35.6 42.5 6.6 48.0 50.8 89.8 33.7 20.3 11.9 32.3 30.9 46.4 24.7 26.4 FOXM1 "FKHL16, HFH-11, HNF-3, INS-1, MPHOSPH2, MPP2, TGT3, trident" ENSG00000111206 "Forkhead box M1" Q08050 12 2857680-2877174 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Cell cycle, DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.0;lymphoid tissue: 32.2;testis: 21.4" "Cell type enhanced" "Detected in many" "Early spermatids: 22.4;Erythroid cells: 18.7;Extravillous trophoblasts: 18.2;Late spermatids: 25.5;Plasma cells: 19.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" CAB017832 Uncertain Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli, Nucleoli rim" Cytosol "CAB017832: " "unprognostic (3.18e-2)" "unprognostic (1.69e-1)" "unprognostic (1.22e-2)" "unprognostic (1.09e-2)" "unprognostic (4.30e-2)" "unprognostic (3.75e-2)" "prognostic unfavorable (1.95e-6)" "prognostic unfavorable (2.92e-4)" "unprognostic (1.01e-2)" "unprognostic (3.25e-2)" "prognostic unfavorable (3.03e-5)" "unprognostic (6.09e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.80e-2)" "unprognostic (1.87e-1)" "unprognostic (1.29e-1)" "unprognostic (1.94e-1)" 1.9 1.1 0.4 9.4 0.5 25.0 1.8 0.8 0.8 1.7 0.2 10.5 9.7 1.7 0.2 11.1 0.8 1.5 0.5 0.8 0.3 0.7 1.2 1.8 11.3 0.4 0.9 0.3 0.4 0.4 0.1 6.1 0.6 0.7 12.5 1.1 1.9 0.8 0.6 6.4 8.8 7.5 0.1 3.1 5.2 21.4 1.0 32.2 0.9 0.3 15.2 3.0 3.2 0.6 133.0 129.5 101.3 92.2 14.2 19.0 129.2 84.0 80.4 165.2 147.2 166.9 114.8 84.5 17.7 119.8 188.5 100.2 153.1 76.1 160.0 159.8 80.3 94.7 121.6 71.6 2.0 79.2 75.0 9.9 8.3 154.4 106.1 39.1 117.8 96.8 55.6 184.9 130.5 122.6 108.3 36.8 225.6 136.1 95.4 77.3 149.8 44.1 38.1 82.7 56.3 89.1 106.7 90.4 46.6 189.4 87.1 87.8 48.0 134.3 200.5 160.4 300.4 24.7 44.3 122.1 63.1 74.3 147.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.4 0.5 0.8 0.8 0.8 0.3 0.4 0.9 0.6 0.1 1.0 0.6 0.1 0.0 1.3 0.7 2.4 2.9 1.3 1.0 1.2 2.0 1.7 1.3 0.5 1.5 0.8 1.8 4.2 7.1 0.8 6.6 1.9 0.2 22.4 1.2 2.1 2.5 0.0 18.7 1.1 0.0 18.2 3.2 10.2 2.4 0.0 15.4 3.6 0.8 9.1 5.0 0.6 7.5 2.0 4.2 1.2 25.5 0.9 2.4 0.0 0.0 1.1 0.6 1.0 0.5 1.0 0.3 0.3 0.7 19.9 1.0 1.4 0.4 0.2 4.0 0.0 1.2 3.0 15.0 9.9 10.2 1.4 1.9 3.3 0.9 12.9 1.9 FRMD8 "FKSG44, FLJ90369, iTAP" ENSG00000126391 "FERM domain containing 8" Q9BZ67 11 65386621-65413525 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 83.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "WM-115: 129.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002861 Approved Approved "Nucleoplasm,Plasma membrane,Centriolar satellite,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 71: Testis - DNA repair" "Cluster 17: WM-115 - Nervous system development" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane, Centriolar satellite" "Nucleoplasm, Cytosol" "HPA002861: AB_1078878" "unprognostic (1.54e-1)" "unprognostic (4.07e-1)" "unprognostic (6.28e-2)" "unprognostic (1.73e-2)" "unprognostic (1.03e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (9.94e-5)" "unprognostic (9.12e-3)" "unprognostic (1.51e-2)" "unprognostic (6.36e-3)" "unprognostic (1.90e-2)" "unprognostic (6.41e-3)" "unprognostic (4.19e-3)" "unprognostic (1.47e-2)" "unprognostic (7.36e-3)" "unprognostic (3.34e-1)" "unprognostic (2.91e-2)" 19.8 17.5 9.6 11.8 11.0 13.0 19.7 12.2 14.5 20.8 9.1 15.0 11.7 14.6 5.3 37.3 15.8 11.6 17.1 13.1 7.9 19.7 13.4 23.5 15.6 12.9 11.3 12.2 23.0 4.0 11.6 10.4 11.4 15.8 6.7 1.7 18.0 6.5 14.8 34.0 23.8 6.6 9.5 40.8 13.4 18.0 11.5 11.1 17.8 5.1 13.6 14.6 26.4 16.2 17.8 22.1 8.7 20.4 23.0 12.0 15.6 20.1 18.1 16.7 12.7 21.2 28.5 21.9 41.9 27.6 11.6 30.3 11.3 16.9 7.0 38.8 10.6 29.9 21.5 11.7 12.4 16.9 44.8 14.9 13.2 15.7 8.2 8.9 26.6 23.2 25.5 23.5 18.3 23.9 26.6 24.6 10.2 13.0 28.7 33.7 16.6 25.2 13.5 21.8 18.9 14.0 15.0 60.1 47.7 7.7 22.0 13.7 23.6 18.4 19.7 26.1 12.3 41.0 22.5 20.4 16.0 10.7 129.8 1.1 12.4 17.7 13.1 13.2 14.1 12.5 9.6 16.7 11.3 9.6 8.8 9.8 23.0 8.2 19.6 13.4 10.8 12.3 9.6 11.0 12.2 14.5 13.1 7.9 12.9 11.3 11.4 9.5 11.5 16.2 30.3 3.2 5.8 2.0 20.5 54.3 22.5 17.7 6.2 5.4 15.4 12.6 7.4 12.8 13.8 12.9 0.0 6.4 25.8 29.3 7.9 21.0 22.3 20.1 12.1 24.8 13.1 24.0 13.4 29.1 15.5 13.0 10.7 23.1 14.0 27.3 37.5 11.0 16.0 5.0 4.9 20.5 8.2 20.2 68.7 4.6 6.2 18.7 19.6 10.3 21.6 4.3 18.6 5.0 10.3 33.8 14.0 7.2 11.9 28.1 32.8 4.6 14.3 4.5 6.6 11.4 14.4 5.3 9.6 24.9 83.5 11.4 21.9 35.2 14.6 35.7 FUT9 Fuc-TIX ENSG00000172461 "Fucosyltransferase 9" Q9Y231 6 96015974-96215612 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 18.9;stomach 1: 23.2" "Cell type enhanced" "Detected in some" "Astrocytes: 776.4;Excitatory neurons: 333.5;Inhibitory neurons: 238.2;Oligodendrocyte precursor cells: 168.9;Oligodendrocytes: 224.7" "Cancer enhanced" "Detected in some" "glioma: 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 2.9;OE19: 2.8;RT4: 6.5;SCLC-21H: 6.3;SK-BR-3: 3.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070923 Approved "Nucleoplasm,Microtubules,Cytokinetic bridge,Cytosol" Yes No "Cluster 22: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "Microtubules, Cytokinetic bridge, Cytosol" "HPA070923: AB_2686323" "unprognostic (1.60e-1)" "unprognostic (2.48e-1)" "unprognostic (5.99e-3)" "unprognostic (1.33e-1)" "unprognostic (2.40e-1)" "unprognostic (2.97e-1)" "unprognostic (1.35e-1)" "unprognostic (2.85e-1)" "unprognostic (1.45e-1)" "unprognostic (1.12e-1)" "unprognostic (6.43e-3)" "unprognostic (5.60e-2)" "unprognostic (1.65e-2)" "unprognostic (3.03e-2)" 0.0 0.4 10.5 0.0 12.6 0.0 0.6 14.5 11.7 0.0 0.0 0.1 2.1 0.2 0.0 0.0 0.2 0.0 0.0 11.8 13.6 0.2 0.0 0.0 0.0 3.4 18.9 0.0 4.8 0.0 0.4 0.4 3.2 0.2 0.0 0.5 0.0 0.2 0.1 0.1 0.0 0.0 5.5 0.0 23.2 0.0 15.3 0.0 0.1 0.0 0.0 0.9 0.0 6.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 1.4 2.8 0.0 0.0 0.0 0.0 0.0 6.5 6.3 0.1 0.0 3.6 0.0 0.1 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 12.6 14.5 11.7 11.8 13.6 3.4 18.9 3.2 5.5 15.3 6.4 0.0 0.0 0.0 776.4 0.2 0.0 0.6 0.0 0.0 4.2 1.4 1.7 0.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.3 0.5 0.1 1.3 0.0 0.0 333.5 2.0 0.0 0.1 56.1 1.4 0.0 0.4 0.0 0.0 0.1 0.0 238.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.1 0.0 0.2 0.0 168.9 224.7 0.5 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.2 GALNT17 "GalNAc-T17, GalNAc-T19, GalNAc-T5L, GALNTL3, ppGalNAc-T17, WBSCR17" ENSG00000185274 "Polypeptide N-acetylgalactosaminyltransferase 17" Q6IS24 7 71132144-71713600 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 55.0;choroid plexus: 46.0;heart muscle: 43.5" "Cell type enhanced" "Detected in some" "Collecting duct cells: 1.8;Endometrial stromal cells: 7.4;Fibroblasts: 1.5;Granulosa cells: 1.7;Theca cells: 2.3" "Cancer enhanced" "Detected in many" "prostate cancer: 8.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 14.3;NTERA-2: 10.8;RPMI-8226: 12.6;SK-BR-3: 45.7;SuSa: 14.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013624, HPA047986" Approved Uncertain "Nucleoplasm,Nucleoli,Nuclear bodies,Golgi apparatus" NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoplasm, Golgi apparatus" "Nucleoli, Nuclear bodies" "HPA013624: AB_1858787, HPA047986: " "unprognostic (2.79e-2)" "unprognostic (6.83e-2)" "unprognostic (5.54e-2)" "unprognostic (3.66e-3)" "unprognostic (1.50e-1)" "unprognostic (2.62e-1)" "unprognostic (6.41e-2)" "unprognostic (5.18e-2)" "unprognostic (1.00e-1)" "prognostic favorable (4.60e-4)" "unprognostic (2.00e-1)" "unprognostic (4.73e-1)" "unprognostic (1.96e-2)" "unprognostic (9.63e-3)" "prognostic favorable (3.91e-4)" "unprognostic (1.92e-1)" "unprognostic (7.94e-3)" 3.2 8.7 30.5 1.9 37.9 0.0 2.0 35.9 51.2 4.0 46.0 16.6 0.3 16.6 3.1 9.3 8.7 2.5 43.5 55.0 3.2 5.7 0.4 9.3 0.0 2.1 3.8 31.6 10.1 1.2 13.3 0.2 3.0 14.7 1.0 3.3 3.3 8.2 4.7 2.2 3.9 8.3 0.0 3.4 2.4 5.0 11.2 2.6 10.1 2.9 1.5 21.2 3.3 24.8 0.0 0.0 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 10.8 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.7 0.0 0.0 45.7 0.0 14.1 0.0 0.0 0.0 0.0 3.8 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.5 37.9 35.9 51.2 55.0 3.2 2.1 3.8 3.0 0.0 11.2 24.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 7.4 0.0 0.0 0.0 0.0 0.7 0.0 1.5 0.0 0.1 0.0 1.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 GAS2 ENSG00000148935 "Growth arrest specific 2" O43903 11 22625509-22813055 "Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell shape, Growth arrest" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 39.7" "Group enriched" "Detected in some" 4 "Astrocytes: 39.8;Excitatory neurons: 114.9;Inhibitory neurons: 141.9;Oligodendrocytes: 83.9" "Cancer enhanced" "Detected in many" "liver cancer: 4.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Hep G2: 43.2;JURKAT: 24.0;Karpas-707: 85.2;SCLC-21H: 24.8;U-266/84: 30.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058904 Enhanced Approved "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" Yes NA "Cluster 30: Non-specific - Translation" "Cluster 85: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "Nucleoplasm, Nucleoli" "HPA058904: AB_2683850" "unprognostic (5.48e-3)" "unprognostic (1.00e-1)" "unprognostic (6.85e-2)" "unprognostic (1.16e-2)" "unprognostic (7.87e-2)" "unprognostic (2.08e-2)" "unprognostic (1.08e-1)" "unprognostic (1.49e-1)" "unprognostic (1.23e-1)" "unprognostic (3.71e-2)" "unprognostic (1.70e-2)" "unprognostic (3.30e-5)" "prognostic favorable (6.13e-4)" "unprognostic (5.85e-2)" "unprognostic (4.22e-2)" "unprognostic (7.94e-2)" "unprognostic (3.58e-2)" 0.4 0.8 2.1 0.3 1.9 0.1 0.8 4.5 5.4 0.9 0.0 0.7 1.8 0.8 0.0 0.7 1.2 1.6 3.5 0.7 2.2 5.4 39.7 1.0 1.0 6.2 7.5 2.0 9.6 0.1 2.5 0.4 6.3 1.0 0.4 2.2 1.5 0.6 4.6 0.8 1.6 0.3 3.3 1.3 2.6 0.8 6.1 8.2 0.8 1.8 0.7 1.0 0.7 6.1 0.0 0.1 1.7 0.0 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.8 0.0 0.0 0.0 0.0 1.0 0.0 0.1 1.7 0.4 0.2 0.0 43.2 0.5 0.1 0.3 0.1 0.1 0.0 0.2 0.3 0.0 24.0 1.6 85.2 0.0 0.4 0.3 0.1 0.3 2.4 0.0 0.9 0.5 4.4 0.0 1.1 24.8 1.3 0.0 0.0 0.5 0.2 0.1 0.0 1.8 0.0 0.4 1.1 0.0 1.1 30.7 0.0 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.1 1.9 4.5 5.4 0.7 2.2 6.2 7.5 6.3 3.3 6.1 6.1 0.1 0.0 0.0 39.8 0.4 0.1 0.4 0.1 0.6 1.9 0.4 0.1 12.7 10.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.4 2.3 1.3 0.1 0.4 0.0 0.0 114.9 3.3 0.0 1.0 3.1 0.7 0.0 0.2 0.7 22.9 0.0 0.0 141.9 0.6 0.0 0.0 0.0 5.4 0.6 0.0 0.0 9.4 0.2 0.2 0.0 18.6 83.9 1.6 1.4 0.0 0.5 0.1 0.1 3.2 4.0 1.2 0.0 0.3 0.8 0.4 1.1 0.6 0.0 0.0 0.4 0.1 0.9 0.3 GET4 "C7orf20, CEE, CGI-20, H_NH1244M04.5, TRC35" ENSG00000239857 "Guided entry of tail-anchored proteins factor 4" Q7L5D6 7 876554-896436 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 36.7;Oligodendrocytes: 15.8;Plasma cells: 37.2;Squamous epithelial cells: 23.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019765 Uncertain Enhanced "Nucleoplasm,Nucleoli,Mitotic chromosome,Cytosol" Yes No "Cluster 26: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Cytosol" "Nucleoli, Mitotic chromosome" "HPA019765: AB_1845750" "unprognostic (2.80e-2)" "unprognostic (2.40e-2)" "unprognostic (2.10e-2)" "unprognostic (9.66e-4)" "unprognostic (9.86e-2)" "unprognostic (8.64e-2)" "unprognostic (4.10e-2)" "unprognostic (1.74e-1)" "unprognostic (2.59e-1)" "unprognostic (6.28e-2)" "unprognostic (2.43e-1)" "unprognostic (1.21e-1)" "unprognostic (7.65e-2)" "unprognostic (8.18e-2)" "unprognostic (1.26e-1)" "unprognostic (5.93e-2)" "unprognostic (9.47e-2)" 25.0 98.0 28.9 12.5 33.7 31.6 26.8 29.7 37.0 28.1 19.1 33.5 20.8 25.5 21.1 43.7 32.1 11.4 33.1 28.8 31.1 68.8 98.4 25.5 15.8 36.1 33.4 34.3 46.1 13.7 70.7 20.5 36.0 37.8 8.8 16.4 28.8 12.3 56.3 46.9 33.6 7.7 29.1 37.5 41.5 79.0 34.0 14.4 34.3 21.9 10.4 31.3 28.9 45.6 78.8 38.1 25.8 38.4 13.2 9.1 81.7 21.2 14.9 26.5 26.6 103.4 95.1 28.5 21.7 12.4 73.7 48.7 29.3 23.3 11.5 11.6 50.9 15.8 31.5 59.5 29.1 27.1 28.1 13.8 27.6 23.4 15.1 19.9 21.1 32.5 103.6 25.7 15.2 59.7 20.8 65.2 93.3 46.1 56.0 43.0 4.5 30.8 23.8 45.4 46.7 50.5 19.5 71.2 32.2 31.5 54.2 47.8 21.4 19.6 43.6 45.7 29.5 38.5 25.9 37.5 20.1 46.2 50.3 22.3 28.5 32.4 23.9 27.6 23.3 24.3 26.4 24.1 29.4 24.5 25.2 27.0 21.9 27.7 35.3 33.3 26.9 24.8 28.9 33.7 29.7 37.0 28.8 31.1 36.1 33.4 36.0 29.1 34.0 45.6 0.3 0.0 3.1 14.7 10.6 1.0 0.3 0.2 14.8 0.8 1.1 0.9 0.6 0.0 2.2 0.0 4.2 1.1 0.7 2.3 0.0 0.9 4.0 2.0 1.1 1.5 0.0 9.2 9.1 0.7 0.7 3.8 36.7 2.8 1.3 1.2 0.0 0.4 0.6 8.4 9.1 2.8 0.0 0.6 0.8 2.7 0.0 6.1 0.0 4.7 0.5 0.2 0.0 10.1 15.8 0.8 1.0 0.0 37.2 0.4 3.6 1.1 2.1 1.4 0.0 0.8 1.8 0.6 1.1 23.5 1.0 1.6 9.9 0.8 1.7 0.8 GFRAL "bA360D14.1, C6orf144, GRAL, UNQ9356" ENSG00000187871 "GDNF family receptor alpha like" Q6UXV0 6 55327469-55402493 "Predicted membrane proteins" Receptor "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047372 Uncertain Approved "Nucleoplasm,Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "Actin filaments, Focal adhesion sites" "HPA047372: AB_2680017" "unprognostic (2.31e-1)" 0.2 0.0 0.2 0.0 0.3 0.0 0.0 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.3 0.3 0.2 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GORAB "FLJ11752, GO, NTKL-BP1, SCYL1BP1" ENSG00000120370 "Golgin, RAB6 interacting" Q5T7V8 1 170532131-170553834 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027250, HPA027746" Approved Supported "Nucleoplasm,Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 59: Non-specific - Transcription" "Golgi apparatus" "Nucleoplasm, Nucleoli, Cytosol" "HPA027250: AB_10611253, HPA027746: " "unprognostic (1.59e-1)" "unprognostic (1.12e-1)" "unprognostic (1.03e-1)" "unprognostic (1.69e-1)" "unprognostic (4.75e-3)" "prognostic favorable (1.39e-4)" "prognostic unfavorable (5.26e-4)" "unprognostic (8.48e-3)" "unprognostic (2.94e-2)" "unprognostic (2.06e-2)" "unprognostic (1.43e-1)" "unprognostic (3.77e-2)" "prognostic unfavorable (7.83e-12)" "unprognostic (2.52e-2)" "unprognostic (2.83e-1)" "unprognostic (7.71e-2)" "unprognostic (1.70e-1)" 3.1 5.2 1.6 1.9 1.6 0.6 2.8 1.6 3.1 3.8 1.9 3.6 1.4 3.2 3.5 2.3 2.1 2.1 3.1 1.5 2.3 2.5 4.3 2.5 3.6 1.6 1.8 4.3 3.7 1.9 3.0 3.1 1.7 2.8 3.3 1.3 3.3 2.6 1.1 1.9 2.7 2.0 1.7 3.1 2.1 2.0 2.0 2.8 3.0 2.1 3.0 3.1 3.3 1.8 3.4 3.8 4.5 2.0 9.0 5.8 2.9 4.8 7.5 3.6 4.6 1.9 4.9 5.1 6.1 4.3 2.4 4.0 6.4 2.8 6.0 4.8 1.6 2.5 4.0 2.8 4.9 4.4 3.1 4.4 2.5 4.2 3.9 5.5 3.5 2.3 4.4 2.3 5.3 0.6 5.8 4.0 4.7 6.2 4.0 3.9 3.8 6.0 4.2 1.9 1.4 3.0 3.6 4.8 11.5 3.1 2.7 8.4 4.4 6.8 3.1 2.9 7.2 3.5 4.4 3.8 5.2 4.0 5.4 0.7 3.9 0.0 2.3 4.2 3.9 2.8 4.1 3.5 4.3 2.8 3.6 3.0 0.5 3.8 3.1 2.7 5.3 2.6 1.6 1.6 1.6 3.1 1.5 2.3 1.6 1.8 1.7 1.7 2.0 1.8 8.1 0.0 11.4 8.8 8.9 2.8 4.0 6.5 8.6 4.7 5.2 7.1 9.4 10.0 7.1 5.5 2.1 6.0 6.2 12.8 3.9 12.3 2.3 5.5 10.4 8.3 0.0 3.4 9.3 6.0 7.3 10.5 9.2 6.7 13.9 5.2 5.3 6.6 7.1 5.0 7.7 9.4 8.2 6.9 4.6 3.2 14.0 5.6 3.6 3.7 10.1 4.3 3.1 9.0 7.3 5.7 9.8 6.4 10.3 4.9 4.3 6.0 2.4 7.1 6.6 8.2 9.3 13.1 8.1 5.4 1.6 5.6 6.3 5.1 6.4 3.0 GPBP1L1 SP192 ENSG00000159592 "GC-rich promoter binding protein 1 like 1" Q9HC44 1 45627304-45688113 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028593 Approved Approved "Nucleoplasm,Plasma membrane,Focal adhesion sites,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Plasma membrane, Focal adhesion sites, Cytosol" "HPA028593: AB_10602906" "unprognostic (1.39e-1)" "unprognostic (8.41e-2)" "unprognostic (1.44e-3)" "unprognostic (6.60e-2)" "unprognostic (6.35e-2)" "unprognostic (1.97e-3)" "unprognostic (2.42e-3)" "unprognostic (9.79e-2)" "unprognostic (3.91e-2)" "unprognostic (1.94e-3)" "unprognostic (1.12e-2)" "unprognostic (4.11e-1)" "unprognostic (1.25e-2)" "unprognostic (6.63e-2)" "unprognostic (4.51e-1)" "unprognostic (7.56e-3)" "unprognostic (6.13e-2)" 28.7 26.7 25.2 31.0 29.4 49.3 40.9 27.3 28.0 35.0 26.1 57.3 54.0 35.6 37.6 45.0 36.2 30.3 41.7 23.6 27.1 47.0 66.3 39.2 39.9 27.7 28.3 30.6 39.3 41.7 25.5 34.1 28.2 35.8 61.2 27.4 42.4 36.1 46.2 47.2 56.7 36.3 26.8 36.9 42.6 57.9 27.4 54.7 48.7 54.9 49.5 35.6 36.7 32.8 41.1 24.7 42.1 44.9 48.4 47.1 57.5 31.9 52.2 44.8 56.1 25.2 44.8 56.3 40.5 43.7 46.9 42.0 46.6 47.8 56.3 64.4 33.4 73.7 28.9 39.2 66.7 74.2 65.1 34.6 102.0 35.3 99.4 60.2 57.7 71.0 63.7 48.7 51.6 22.0 66.2 65.8 60.4 54.8 27.7 43.0 55.1 41.9 51.5 40.2 51.9 34.7 52.6 76.6 83.5 81.6 35.1 86.2 49.8 32.0 33.6 35.2 48.9 47.2 46.9 41.3 34.0 60.6 34.5 24.0 21.6 40.3 21.6 27.3 22.9 16.5 20.9 21.1 23.0 14.1 22.6 22.4 22.6 26.6 30.6 13.1 26.4 21.1 25.2 29.4 27.3 28.0 23.6 27.1 27.7 28.3 28.2 26.8 27.4 32.8 43.3 60.9 24.4 54.5 45.1 64.9 41.2 28.3 59.2 23.5 51.3 33.5 46.9 41.5 34.3 60.7 35.5 26.2 47.5 96.8 50.9 33.0 23.4 38.1 32.2 38.6 38.3 62.1 48.5 38.9 33.7 25.4 44.9 47.5 59.6 24.3 37.5 81.3 25.0 37.0 49.0 67.2 32.6 49.9 51.6 17.6 20.5 46.1 23.2 70.3 41.3 18.2 45.3 50.8 93.8 51.2 57.0 21.4 36.6 62.8 75.5 58.7 33.0 32.9 19.7 22.4 42.0 78.9 75.3 71.7 67.8 45.4 47.1 27.7 68.6 78.2 GPER1 "CEPR, CMKRL2, DRY12, FEG-1, GPCR-Br, GPER, GPR30, LERGU, LERGU2, LyGPR" ENSG00000164850 "G protein-coupled estrogen receptor 1" Q99527 7 1082208-1093815 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Cell cycle, Differentiation, Immunity, Inflammatory response, Innate immunity, Neurogenesis" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 45.3" "Cell type enhanced" "Detected in many" "Adipocytes: 9.6;Distal enterocytes: 15.4;Endothelial cells: 11.3;Hepatocytes: 23.5;Kupffer cells: 16.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.9;intermediate monocyte: 2.8;myeloid DC: 5.8" "Group enriched" "Detected in many" 19 "dendritic cells: 5.8;monocytes: 2.9" "Cell line enhanced" "Detected in many" "AN3-CA: 11.5;Daudi: 12.1;fHDF/TERT166: 8.6;Hep G2: 22.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016718, HPA027052" Approved Approved Nucleoplasm,Nucleoli,Vesicles,Cytosol NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Nucleoli "Nucleoplasm, Vesicles, Cytosol" "HPA016718: , HPA027052: AB_10612112" "unprognostic (4.74e-2)" "unprognostic (1.32e-1)" "unprognostic (3.09e-2)" "prognostic favorable (1.17e-4)" "unprognostic (2.17e-1)" "unprognostic (6.17e-2)" "unprognostic (3.45e-1)" "unprognostic (6.38e-2)" "unprognostic (2.40e-1)" "unprognostic (1.23e-1)" "unprognostic (1.42e-2)" "unprognostic (2.49e-1)" "unprognostic (2.37e-2)" "unprognostic (1.79e-2)" "unprognostic (1.58e-1)" "unprognostic (7.26e-2)" "unprognostic (7.78e-2)" 10.6 12.6 12.7 1.5 11.7 0.2 8.4 9.0 15.9 5.4 8.1 10.8 0.6 5.8 0.3 2.2 4.3 1.2 7.1 10.0 9.6 9.7 27.9 12.1 1.9 9.9 10.2 2.4 2.1 0.4 6.1 6.3 10.5 7.2 1.4 0.9 2.9 5.0 4.3 2.8 3.6 1.8 8.4 8.5 45.3 1.5 11.6 0.9 9.7 1.3 1.0 6.1 4.7 9.2 1.1 0.4 0.3 11.5 2.7 2.6 1.1 6.7 4.4 2.1 3.7 0.2 0.3 12.1 1.1 8.6 0.1 0.6 0.1 0.0 0.2 2.6 2.1 0.0 1.4 22.8 0.4 0.1 0.7 1.5 0.0 1.3 0.0 1.6 0.6 0.2 0.1 0.1 0.5 0.8 0.0 0.4 2.2 2.4 7.9 1.1 0.0 0.0 0.2 0.0 0.1 4.5 0.0 0.5 2.5 0.8 0.2 0.1 1.6 0.4 2.8 6.9 2.1 0.0 0.0 4.4 3.8 0.2 0.2 0.0 2.9 0.0 0.0 2.8 0.0 0.2 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 1.4 12.7 11.7 9.0 15.9 10.0 9.6 9.9 10.2 10.5 8.4 11.6 9.2 9.6 0.0 0.0 1.0 1.2 0.5 0.0 0.5 1.8 0.0 0.5 0.5 2.8 0.0 0.0 5.5 0.0 0.0 0.0 15.4 0.0 0.1 0.0 4.4 0.1 11.3 1.2 0.0 0.8 3.1 0.6 1.5 0.5 1.0 0.0 0.4 1.1 23.5 0.6 0.0 0.5 2.8 0.0 16.9 2.7 0.7 2.8 2.9 0.0 1.9 0.6 4.4 0.0 0.5 0.1 0.8 7.4 1.2 0.1 0.8 0.2 5.6 0.0 0.4 0.0 0.7 7.2 0.5 2.7 0.1 0.3 0.0 0.0 0.1 2.0 0.1 GPR27 SREB1 ENSG00000170837 "G protein-coupled receptor 27" Q9NS67 3 71753855-71756496 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 22.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 10.3;Breast myoepithelial cells: 7.5;Collecting duct cells: 12.9;Glandular and luminal cells: 8.1;monocytes: 8.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "eosinophil: 2.8;neutrophil: 7.2" "Lineage enriched" "Detected in single" 12 "granulocytes: 7.2" "Cell line enhanced" "Detected in some" "EFO-21: 17.9;HL-60: 17.5;MCF7: 14.6;NTERA-2: 28.9;RPTEC TERT1: 13.6;SH-SY5Y: 10.9;T-47d: 9.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029395 Approved Approved "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "Plasma membrane, Actin filaments, Cytosol" "HPA029395: AB_10602907" "prognostic favorable (5.63e-4)" "unprognostic (2.99e-1)" "unprognostic (3.23e-2)" "unprognostic (3.22e-1)" "unprognostic (7.14e-3)" "unprognostic (1.50e-2)" "unprognostic (2.17e-2)" "unprognostic (1.18e-2)" "unprognostic (3.22e-1)" "prognostic favorable (1.21e-6)" "unprognostic (2.97e-3)" "unprognostic (4.97e-2)" "unprognostic (1.51e-2)" "unprognostic (1.21e-2)" "unprognostic (2.71e-2)" "unprognostic (1.45e-2)" "unprognostic (6.79e-2)" 1.4 4.0 21.3 1.5 22.9 15.7 3.9 13.0 19.7 3.5 7.4 1.6 0.3 5.0 2.8 3.7 6.8 1.0 3.4 19.9 20.6 3.2 0.1 1.4 0.2 18.0 18.3 4.4 3.1 17.3 9.2 1.2 16.2 5.1 0.5 1.8 1.4 4.3 0.7 2.1 0.7 2.9 19.7 3.3 2.0 4.7 22.9 0.5 6.2 1.9 0.2 2.0 2.3 18.9 0.0 1.1 1.9 2.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 17.9 0.0 0.8 0.1 4.3 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.1 17.5 0.9 0.0 2.9 0.0 1.2 0.0 0.0 3.7 0.0 0.0 0.0 14.6 1.2 0.2 28.9 0.0 0.0 0.0 0.0 0.0 13.6 7.8 3.0 10.9 3.8 0.0 0.0 3.6 9.9 0.0 0.0 0.0 7.7 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.5 2.8 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.1 7.2 0.0 0.1 0.0 0.0 0.1 21.3 22.9 13.0 19.7 19.9 20.6 18.0 18.3 16.2 19.7 22.9 18.9 0.2 0.0 1.1 0.0 0.1 1.9 4.2 0.0 4.0 10.3 6.5 7.5 3.5 2.8 1.3 12.9 4.2 1.4 0.4 0.2 1.9 0.7 0.2 2.1 4.9 0.4 1.2 1.7 0.0 0.0 1.3 1.2 1.1 8.1 0.0 2.4 0.4 0.0 0.9 0.0 0.0 0.0 0.0 4.4 0.3 0.0 0.9 3.2 0.0 0.0 8.6 0.5 1.0 0.0 0.0 0.3 0.1 1.2 0.0 5.6 0.0 0.1 1.5 0.4 0.0 2.3 1.7 0.2 4.8 4.7 1.7 0.3 0.7 0.5 0.3 2.0 GPR37L1 ETBR-LP-2 ENSG00000170075 "G protein-coupled receptor 37 like 1" O60883 1 202122917-202133592 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 76.4" "Cell type enhanced" "Detected in some" "Astrocytes: 91.7;Muller glia cells: 59.6;Oligodendrocyte precursor cells: 89.0;Oligodendrocytes: 20.4" "Cancer enriched" "Detected in some" 57 "glioma: 36.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HaCaT: 1.2;MCF7: 1.5;T-47d: 3.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061629, HPA064454" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 6: T47d - Mammary gland" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Cell Junctions" "Vesicles, Plasma membrane" "HPA061629: , HPA064454: AB_2685268" "unprognostic (2.12e-2)" "unprognostic (1.83e-1)" "unprognostic (2.96e-1)" "unprognostic (1.61e-3)" "unprognostic (4.52e-1)" "unprognostic (8.20e-2)" "unprognostic (2.26e-4)" "unprognostic (5.83e-2)" "unprognostic (3.46e-3)" "unprognostic (2.07e-1)" "unprognostic (1.83e-1)" "unprognostic (3.28e-2)" "unprognostic (4.86e-3)" "unprognostic (1.14e-1)" "unprognostic (4.58e-2)" "unprognostic (1.18e-3)" "unprognostic (3.49e-1)" 0.1 0.2 55.2 0.0 71.1 0.2 0.0 60.7 52.2 0.2 10.6 0.9 0.2 0.1 0.1 0.1 0.1 0.0 0.1 48.0 50.7 0.0 0.2 0.0 0.0 66.7 67.0 0.0 0.0 0.0 0.6 0.0 53.7 0.2 0.2 2.8 0.1 0.3 0.1 0.1 0.3 0.1 59.4 0.0 0.2 0.3 76.4 0.0 0.1 0.1 0.0 0.0 0.1 53.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.5 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 55.2 71.1 60.7 52.2 48.0 50.7 66.7 67.0 53.7 59.4 76.4 53.1 0.0 0.0 0.0 91.7 0.1 0.4 0.5 0.7 0.0 1.2 0.3 0.3 1.1 1.5 1.7 0.0 4.2 0.1 0.0 4.9 0.0 3.2 4.5 0.9 0.2 0.1 0.0 0.0 0.4 1.2 1.0 0.2 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.5 1.1 0.0 0.0 0.0 0.8 0.9 0.1 0.0 2.8 0.0 59.6 0.0 89.0 20.4 2.1 2.7 1.9 0.0 0.8 1.3 0.1 1.1 4.9 0.0 0.5 0.1 0.0 0.1 0.0 0.1 0.7 0.1 0.2 0.7 1.0 GSDMA "FLJ39120, GSDM, GSDM1" ENSG00000167914 "Gasdermin A" Q96QA5 17 39953263-39977768 "Predicted intracellular proteins, Transporters" Necrosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "skin 1: 58.9" "Group enriched" "Detected in some" 5 "Collecting duct cells: 3.7;Hofbauer cells: 5.0;Kupffer cells: 5.6;Macrophages: 2.6;Suprabasal keratinocytes: 2.7;Theca cells: 2.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 7.6" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HBEC3-KT: 4.1;hTCEpi: 2.7;hTERT-HME1: 5.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA023313, HPA064826" Enhanced Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA 44000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA023313: AB_1850378, HPA064826: AB_2685361" "unprognostic (1.32e-2)" "unprognostic (2.01e-1)" "unprognostic (2.95e-2)" "unprognostic (1.06e-1)" "unprognostic (3.62e-1)" "unprognostic (1.97e-1)" "unprognostic (7.77e-2)" "unprognostic (1.39e-1)" "unprognostic (3.24e-1)" "unprognostic (3.52e-2)" "unprognostic (2.71e-1)" "unprognostic (2.90e-2)" "unprognostic (1.06e-2)" "unprognostic (9.86e-2)" "unprognostic (7.45e-2)" "unprognostic (3.63e-2)" "unprognostic (3.79e-2)" 3.4 0.7 0.2 0.9 0.2 0.4 3.5 0.4 0.4 0.8 0.2 0.7 0.6 0.4 6.6 3.2 0.3 0.8 0.3 0.3 0.2 0.3 0.3 0.4 0.7 0.4 0.0 0.1 0.3 1.3 0.1 1.6 0.4 0.1 1.2 0.0 0.8 0.0 0.4 58.9 0.5 0.6 0.0 0.2 0.3 0.3 0.4 0.5 0.1 0.1 3.4 1.1 1.5 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 4.1 0.0 0.1 0.2 0.5 0.4 0.2 0.0 0.1 0.8 0.0 2.7 0.5 5.4 0.0 0.0 0.0 0.1 1.3 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.5 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.4 0.0 0.0 0.1 0.0 0.3 0.2 0.0 0.0 0.9 0.1 0.1 2.2 0.0 2.6 0.0 1.3 0.8 0.1 0.1 0.6 0.9 0.7 0.1 0.1 0.2 0.5 0.5 0.2 0.2 0.4 0.4 0.3 0.2 0.4 0.0 0.4 0.0 0.4 0.4 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 3.7 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.2 0.2 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.1 0.7 0.0 5.0 0.0 0.1 0.7 0.0 5.6 0.6 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.7 0.0 0.2 2.8 0.0 0.0 H1-0 "H1.0, H1F0, H1FV" ENSG00000189060 "H1.0 linker histone" P07305 22 37805093-37807436 "Plasma proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 660.5" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 51.4;Cytotrophoblasts: 42.9;Extravillous trophoblasts: 125.7;Hofbauer cells: 73.2;Syncytiotrophoblasts: 219.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 8.1;granulocytes: 17.1;monocytes: 11.7" "Cell line enhanced" "Detected in many" "OE19: 662.8;U-2 OS: 823.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000843 Supported Supported "Nucleoplasm,Nuclear bodies,Golgi apparatus,Actin filaments" Yes No 120000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Nuclear bodies" "Golgi apparatus, Actin filaments" "HPA000843: AB_1079062" "unprognostic (1.29e-2)" "unprognostic (1.68e-1)" "unprognostic (1.69e-2)" "unprognostic (1.27e-1)" "unprognostic (3.31e-3)" "unprognostic (1.19e-1)" "unprognostic (2.18e-1)" "unprognostic (3.85e-1)" "unprognostic (7.68e-2)" "unprognostic (1.86e-1)" "unprognostic (5.95e-3)" "unprognostic (4.86e-3)" "prognostic favorable (7.68e-7)" "unprognostic (3.40e-1)" "unprognostic (1.47e-1)" "unprognostic (1.37e-3)" "unprognostic (1.73e-1)" 89.8 53.5 56.6 36.7 55.4 660.5 121.4 72.5 64.1 218.3 42.5 146.2 129.9 168.2 43.5 230.6 119.7 56.3 86.5 55.4 67.1 292.8 179.3 72.4 24.4 58.4 54.2 120.7 125.9 93.2 58.2 80.0 57.7 151.7 120.0 39.9 155.3 40.2 216.2 228.6 137.1 97.7 52.6 36.7 131.2 42.4 58.3 136.2 93.9 93.5 46.6 85.6 194.9 55.8 159.6 67.9 206.0 91.8 53.4 48.4 291.6 126.9 262.3 362.6 512.6 278.1 247.3 0.2 31.1 106.3 84.1 303.8 0.0 87.2 256.0 0.9 15.3 268.2 25.3 187.4 185.8 0.1 0.7 45.4 152.4 182.3 203.2 4.0 97.8 60.4 0.1 0.5 28.5 263.3 45.4 26.5 80.2 662.8 329.9 74.6 122.6 56.1 58.0 42.7 47.3 263.9 349.9 235.4 473.9 91.8 184.2 167.1 65.4 27.4 823.3 122.7 25.9 0.7 18.5 1.2 33.5 95.9 80.3 17.1 9.9 15.7 0.1 11.7 0.1 0.0 1.0 0.2 8.1 0.1 2.8 0.4 5.4 0.1 10.3 7.4 0.2 6.9 56.6 55.4 72.5 64.1 55.4 67.1 58.4 54.2 57.7 52.6 58.3 55.8 19.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 51.4 0.0 0.0 0.0 0.0 42.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 125.7 25.2 0.0 0.0 0.0 0.0 0.0 0.0 73.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.5 0.0 0.0 0.0 0.0 219.7 0.0 0.0 0.0 0.0 HIVEP1 "CIRIP, CRYBP1, MBP-1, PRDII-BF1, Schnurri-1, ZAS1, ZNF40, ZNF40A" ENSG00000095951 "HIVEP zinc finger 1" P15822 6 12008762-12164999 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 94.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050724, HPA067457" Approved Supported "Nucleoplasm,Nuclear bodies,Mitochondria,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "Nuclear bodies, Mitochondria, Cytosol" "HPA050724: AB_2616457, HPA067457: " "unprognostic (2.55e-1)" "unprognostic (5.85e-2)" "unprognostic (1.15e-1)" "unprognostic (6.03e-2)" "unprognostic (1.75e-2)" "unprognostic (5.65e-3)" "unprognostic (4.83e-2)" "unprognostic (1.38e-1)" "unprognostic (2.20e-1)" "unprognostic (1.85e-1)" "unprognostic (5.69e-2)" "unprognostic (1.98e-1)" "unprognostic (4.40e-2)" "unprognostic (3.01e-2)" "unprognostic (2.21e-1)" "unprognostic (4.49e-2)" "unprognostic (2.38e-1)" 7.2 2.3 0.8 8.0 3.0 16.7 5.5 0.7 3.0 7.4 6.5 6.4 5.0 5.9 4.5 7.4 6.1 7.3 3.8 2.2 0.8 4.5 11.7 6.3 8.0 1.3 2.8 6.5 6.7 10.5 3.3 4.9 0.5 6.9 6.6 5.8 4.8 5.8 2.8 5.7 5.2 6.2 0.0 6.0 4.9 4.8 1.2 9.1 4.9 6.2 8.3 9.3 3.3 1.6 8.1 5.9 7.5 4.2 5.8 7.3 7.2 6.4 5.5 5.2 5.7 3.8 4.2 6.7 13.6 7.8 12.4 7.6 7.4 9.2 7.1 14.6 4.3 3.1 5.6 3.7 4.7 3.7 2.5 5.1 9.0 10.6 16.3 11.0 15.5 4.6 32.9 7.5 11.5 6.0 5.9 3.3 6.4 2.8 2.7 3.2 9.8 10.7 3.1 8.7 7.1 5.2 15.9 12.8 4.3 16.6 7.6 4.7 25.2 13.0 5.8 12.3 7.4 30.0 27.3 12.0 4.0 4.8 5.5 2.4 1.8 2.1 1.2 2.0 0.9 3.1 2.0 0.8 1.2 4.8 3.4 2.1 11.7 3.3 5.2 9.0 4.4 0.7 0.8 3.0 0.7 3.0 2.2 0.8 1.3 2.8 0.5 0.0 1.2 1.6 40.2 28.9 16.9 74.7 35.6 32.2 25.4 7.4 30.7 20.4 12.3 10.9 10.4 17.2 17.6 7.3 12.5 3.4 18.7 17.5 3.9 5.6 2.5 37.7 16.4 20.3 10.8 6.5 94.6 7.2 1.8 25.2 22.4 51.0 7.6 7.0 6.4 12.3 5.9 21.9 68.3 14.4 4.1 9.6 47.9 1.8 3.7 23.1 19.6 44.0 29.6 13.1 5.2 59.3 25.0 11.5 10.3 4.5 33.6 25.2 6.7 2.5 16.7 9.7 0.0 21.0 17.1 3.9 3.5 18.7 33.4 5.2 18.8 6.6 8.6 23.7 HJURP "DKFZp762E1312, FAKTS, hFLEG1, URLC9" ENSG00000123485 "Holliday junction recognition protein" Q8NCD3 2 233833416-233854566 "Predicted intracellular proteins" "Cell cycle" "Chaperone, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 47.4;lymphoid tissue: 30.4" "Cell type enhanced" "Detected in many" "Early spermatids: 17.4;Erythroid cells: 38.3;Extravillous trophoblasts: 16.1;Granulosa cells: 14.8;Spermatocytes: 37.5;Spermatogonia: 16.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA008436, HPA027261" Uncertain Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitochondria" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli, Nucleoli rim" Mitochondria "HPA008436: AB_1850757, HPA027261: AB_2672184" "unprognostic (5.63e-2)" "unprognostic (9.15e-2)" "unprognostic (1.87e-1)" "unprognostic (1.44e-3)" "unprognostic (3.62e-1)" "unprognostic (1.75e-1)" "prognostic unfavorable (3.37e-5)" "prognostic unfavorable (2.46e-4)" "prognostic unfavorable (6.49e-4)" "unprognostic (9.48e-2)" "prognostic unfavorable (7.72e-5)" "unprognostic (7.60e-2)" "unprognostic (0.00e+0)" "unprognostic (7.42e-2)" "unprognostic (5.58e-2)" "unprognostic (1.89e-2)" "unprognostic (5.74e-2)" 0.6 0.6 0.0 5.5 0.1 47.4 1.1 0.1 0.2 0.8 0.1 3.9 4.1 0.9 0.2 5.6 0.3 0.5 0.3 0.1 0.1 0.4 0.8 1.4 12.6 0.1 0.3 0.2 0.2 0.1 0.1 3.0 0.1 0.4 5.2 0.1 1.0 0.1 0.2 3.6 3.8 1.9 0.0 4.1 2.4 11.1 0.3 30.4 0.3 0.0 12.0 1.4 2.0 0.2 54.5 73.6 68.4 32.7 2.6 5.4 42.8 79.5 37.9 55.2 59.9 51.3 57.6 17.1 9.0 31.4 98.0 61.7 54.9 40.9 72.6 40.0 21.6 65.5 61.4 50.9 0.3 54.1 43.2 1.8 1.5 45.1 30.9 15.7 35.5 51.3 56.6 40.8 103.0 55.3 76.4 59.7 58.9 42.2 49.1 58.4 103.0 30.3 28.6 32.3 39.4 24.7 45.8 34.2 31.7 31.0 25.7 42.1 26.0 59.6 64.6 44.3 87.2 38.6 32.7 67.9 35.7 39.3 151.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.4 0.0 1.2 0.4 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.3 0.1 0.0 0.3 0.2 0.2 0.0 0.5 0.0 2.9 1.3 0.5 1.9 0.0 0.0 0.7 0.5 1.2 0.0 2.1 0.0 0.0 8.2 0.5 5.6 0.0 0.2 17.4 0.3 1.3 1.1 0.0 38.3 0.0 0.0 16.1 2.0 5.1 1.3 0.0 14.8 2.2 0.3 7.1 0.0 0.0 3.5 0.0 3.0 2.9 9.0 0.6 3.5 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.0 11.4 1.0 0.5 0.1 0.1 0.0 0.0 0.1 1.9 37.5 16.3 8.9 0.9 1.5 2.3 0.3 7.6 0.9 HNF4G NR2A2 ENSG00000164749 "Hepatocyte nuclear factor 4 gamma" Q14541 8 75407914-75566834 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "intestine: 114.6" "Cell type enhanced" "Detected in many" "Astrocytes: 39.8;Distal enterocytes: 51.0;Intestinal goblet cells: 32.3;Paneth cells: 54.3;Proximal enterocytes: 165.3;Undifferentiated cells: 36.9" "Group enriched" "Detected in many" 5 "colorectal cancer: 8.5;liver cancer: 2.8;pancreatic cancer: 4.0;renal cancer: 4.6;stomach cancer: 10.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 4.3;CAPAN-2: 16.1;Karpas-707: 4.5;OE19: 10.0;PC-3: 4.8;THP-1: 5.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005438, HPA010610" Enhanced Enhanced "Nucleoplasm,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA005438: AB_1850822, HPA010610: AB_2668318" "unprognostic (2.09e-1)" "unprognostic (2.90e-1)" "unprognostic (1.77e-2)" "unprognostic (9.44e-2)" "unprognostic (5.60e-2)" "unprognostic (4.65e-2)" "unprognostic (5.26e-2)" "unprognostic (1.27e-2)" "unprognostic (3.92e-1)" "unprognostic (8.09e-2)" "unprognostic (3.68e-2)" "unprognostic (1.83e-2)" "unprognostic (6.93e-3)" "unprognostic (1.67e-2)" "unprognostic (2.11e-1)" "unprognostic (4.22e-2)" "unprognostic (2.47e-2)" 0.2 0.0 0.2 2.5 0.5 0.0 1.0 0.2 0.3 2.3 0.1 20.6 100.5 0.4 1.2 0.3 1.0 12.1 0.0 0.3 0.3 17.4 12.9 0.2 0.1 0.4 0.5 0.0 5.6 0.0 0.0 0.1 0.3 0.6 19.6 0.0 0.4 0.4 0.0 0.0 114.6 0.9 0.4 0.1 8.1 3.0 0.3 0.0 0.0 0.0 0.0 1.0 0.0 0.3 1.1 4.3 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.3 16.1 0.0 2.2 0.0 1.8 0.0 2.0 0.0 0.0 0.0 1.8 0.0 0.0 2.9 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.5 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.3 0.3 10.0 4.8 0.0 0.0 0.3 2.7 0.1 0.3 1.6 0.3 0.1 0.0 0.2 0.2 5.5 0.0 0.3 0.1 0.1 0.0 1.1 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.2 0.3 0.3 0.3 0.4 0.5 0.3 0.4 0.3 0.3 0.0 0.0 1.1 39.8 0.5 0.0 0.6 0.4 2.2 0.0 1.3 0.5 0.2 17.2 1.5 3.7 0.0 0.0 0.0 51.0 5.9 3.2 3.1 3.6 0.2 0.0 16.3 0.0 0.5 4.3 0.0 0.1 8.2 3.2 0.0 0.0 0.0 10.7 0.0 0.0 0.6 32.3 2.0 0.0 0.0 5.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 26.2 0.6 5.6 54.3 0.0 0.0 1.6 165.3 18.5 8.1 0.0 0.0 0.1 0.4 4.8 0.0 0.4 0.0 0.0 0.2 0.0 36.9 2.9 HS6ST3 ENSG00000185352 "Heparan sulfate 6-O-sulfotransferase 3" Q8IZP7 13 96090107-96839562 "Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.5" "Group enriched" "Detected in some" 27 "Excitatory neurons: 1308.8;Inhibitory neurons: 893.1;Oligodendrocyte precursor cells: 968.6" "Cancer enhanced" "Detected in many" "breast cancer: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "RT4: 17.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA078257 Approved "Nucleoplasm,Nuclear membrane,Plasma membrane,Actin filaments" "Intracellular and membrane" NA NA 24000 "Cluster 10: Brain - Neuronal signaling" "Cluster 15: RT4 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Nuclear membrane" "Plasma membrane, Actin filaments" "HPA078257: AB_2732374" "unprognostic (2.34e-2)" "unprognostic (1.90e-2)" "unprognostic (2.82e-2)" "unprognostic (1.72e-2)" "unprognostic (4.88e-2)" "unprognostic (2.78e-2)" "unprognostic (1.55e-1)" "unprognostic (3.67e-3)" "unprognostic (8.11e-3)" "unprognostic (1.19e-1)" "prognostic favorable (6.12e-5)" "unprognostic (1.54e-4)" "unprognostic (2.24e-1)" "unprognostic (1.57e-3)" "unprognostic (9.89e-2)" 1.4 4.2 1.4 0.2 3.5 0.0 0.3 0.0 9.0 1.8 0.0 0.2 0.4 2.1 2.1 0.4 0.5 0.2 0.9 12.5 7.3 0.8 0.0 0.0 0.0 0.1 5.2 0.1 2.2 2.1 1.9 0.0 0.3 0.2 0.1 2.2 0.0 0.2 1.1 0.5 0.4 1.5 0.3 0.0 0.9 0.3 6.1 0.0 2.4 0.0 0.0 2.7 0.2 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.1 0.0 0.0 1.1 0.0 1.2 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 17.3 0.9 0.7 0.1 0.1 0.0 0.2 0.5 0.0 0.2 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 3.5 0.0 9.0 12.5 7.3 0.1 5.2 0.3 0.3 6.1 0.0 0.0 0.0 0.0 33.6 0.0 0.0 0.0 0.0 0.0 3.9 0.3 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.3 0.6 0.1 0.0 0.0 1308.8 0.6 0.1 0.1 0.0 2.5 0.0 0.0 0.0 0.0 0.0 3.3 893.1 0.0 0.0 0.0 0.0 1.0 0.6 0.0 0.0 38.4 0.0 0.9 0.0 968.6 16.5 0.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.2 0.0 0.1 1.8 0.1 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 IDO1 "IDO, INDO" ENSG00000131203 "Indoleamine 2,3-dioxygenase 1" P14902 8 39902275-39928790 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Immunity, Tryptophan catabolism" "Dioxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 58.7;placenta: 110.9" "Cell type enriched" "Detected in many" 11 "monocytes: 2612.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 14 "eosinophil: 465.0" "Lineage enriched" "Detected in many" 18 "granulocytes: 465.0" "Cell line enriched" "Detected in some" 7 "EFO-21: 61.8" "Region enriched" "Detected in many" 12 "basal ganglia: 34.1" "Low region specificity" "Detected in all" "HPA023072, HPA023149, HPA027772, CAB072820" Enhanced Supported Nucleoplasm,Vesicles,Mitochondria,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 38: EFO-21 - Unknown function" "Cluster 3: Monocytes - Immune response regulation" Cytosol "Nucleoplasm, Vesicles, Mitochondria" "CAB072820: , HPA023072: AB_1846220, HPA023149: AB_1846221, HPA027772: AB_1846222" "unprognostic (1.68e-2)" "unprognostic (1.71e-2)" "unprognostic (4.08e-3)" "unprognostic (7.21e-3)" "unprognostic (1.90e-1)" "unprognostic (1.09e-2)" "unprognostic (1.86e-1)" "unprognostic (3.06e-2)" "prognostic favorable (5.27e-4)" "prognostic favorable (3.32e-4)" "unprognostic (3.59e-2)" "unprognostic (2.74e-1)" "prognostic unfavorable (1.12e-7)" "unprognostic (4.18e-2)" "unprognostic (4.42e-2)" "unprognostic (1.16e-1)" "unprognostic (1.97e-2)" 9.8 0.7 0.6 40.5 0.4 0.7 2.0 0.4 0.8 7.2 1.0 5.3 10.3 10.2 1.2 1.3 2.6 6.2 1.8 0.4 0.6 1.7 2.4 25.9 58.7 0.7 0.3 1.2 1.2 0.2 0.1 110.9 0.5 2.0 8.2 1.3 1.9 3.0 8.1 1.3 8.4 2.4 0.4 23.0 5.8 1.1 0.8 31.2 4.0 0.6 31.5 9.1 0.5 0.6 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.9 7.6 4.8 0.3 0.8 0.0 61.8 0.0 3.3 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.1 0.4 0.1 0.0 0.0 0.2 0.0 0.3 0.4 0.1 0.0 0.1 0.0 0.1 0.0 0.1 8.4 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 2.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 9.1 0.2 0.2 0.0 0.3 0.0 32.5 1.3 465.0 0.1 1.4 0.1 0.2 0.1 0.0 26.4 0.3 0.1 0.2 4.9 0.1 0.1 0.3 0.1 1.2 0.6 0.4 0.4 0.8 0.4 0.6 0.7 0.3 0.5 0.4 0.8 0.6 24.9 0.0 0.5 0.7 4.4 0.4 0.2 18.3 0.0 0.0 0.5 0.1 0.3 0.0 76.0 0.0 0.0 0.0 0.3 8.3 0.0 4.4 3.7 70.1 23.0 6.9 0.0 0.0 0.2 8.1 0.0 0.3 0.0 223.3 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 2.0 3.7 28.1 1.8 0.0 13.6 0.0 0.0 2612.3 3.0 0.0 0.0 0.1 0.4 0.0 0.4 2.4 0.5 0.0 0.0 33.3 0.2 0.0 1.2 8.4 0.0 0.1 0.1 0.6 0.0 1.3 0.0 1.3 2.0 IL13RA2 "CD213a2, CT19, IL-13R, IL13BP" ENSG00000123496 "Interleukin 13 receptor subunit alpha 2" Q14627 X 115003975-115019977 "Cancer-related genes, CD markers, Predicted membrane proteins" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 12.0;testis: 30.0" "Cell type enriched" "Detected in some" 5 "Early spermatids: 322.4" "Cancer enhanced" "Detected in many" "glioma: 17.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "PC-3: 133.0;U-2197: 425.6;U-251 MG: 297.4;U-87 MG: 167.9" "Region enhanced" "Detected in many" "olfactory bulb: 7.0" "Low region specificity" "Detected in some" "HPA045831, HPA067363" Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 18: U-2197 - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane, Cell Junctions" "Nucleoplasm, Vesicles" "HPA045831: , HPA067363: " "unprognostic (1.97e-1)" "unprognostic (2.83e-1)" "unprognostic (6.62e-4)" "unprognostic (7.39e-2)" "unprognostic (8.45e-2)" "unprognostic (1.80e-1)" "prognostic favorable (3.55e-4)" "unprognostic (3.54e-1)" "unprognostic (2.85e-1)" "unprognostic (1.92e-2)" "unprognostic (2.20e-3)" "unprognostic (2.19e-2)" "unprognostic (1.53e-5)" "unprognostic (1.58e-1)" "unprognostic (1.63e-1)" "unprognostic (9.70e-3)" "unprognostic (1.20e-1)" 0.8 4.8 1.3 4.0 1.9 0.0 0.4 0.1 1.1 1.1 1.6 0.4 0.3 0.8 4.4 0.6 0.1 0.8 0.7 1.5 10.6 3.6 10.0 1.4 0.1 3.1 3.7 0.1 0.1 0.5 12.0 0.4 1.8 4.1 0.7 0.0 0.9 3.5 0.0 0.2 0.3 0.3 0.7 0.2 0.1 30.0 6.1 2.1 1.2 0.1 0.1 4.4 0.2 0.8 0.4 0.0 4.6 0.1 0.7 3.6 0.0 29.2 28.0 0.1 0.1 0.0 0.0 0.0 0.5 14.6 46.6 0.1 0.0 5.2 0.0 0.1 0.0 0.0 0.0 0.0 2.6 0.0 0.1 4.8 0.8 4.6 26.9 0.4 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.1 133.0 0.0 0.0 0.0 2.4 0.2 0.0 6.8 2.1 0.3 0.4 0.0 0.1 0.4 0.0 14.7 0.4 425.6 297.4 0.0 0.2 0.1 167.9 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.9 0.1 1.1 1.5 10.6 3.1 3.7 1.8 0.7 6.1 0.8 0.3 0.0 0.0 0.0 0.1 0.1 4.7 0.3 0.0 0.0 0.0 0.0 0.2 1.5 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 322.4 0.4 0.3 1.3 4.2 0.0 0.4 0.0 0.0 10.3 0.0 0.4 0.0 0.0 46.4 0.4 0.0 0.0 0.6 0.0 0.0 2.8 0.3 58.6 2.8 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.2 8.5 0.0 4.9 0.1 10.9 0.0 0.0 2.9 0.0 0.0 0.0 3.4 63.1 4.0 0.0 0.0 0.0 0.1 0.0 0.0 2.3 IL1R1 "CD121A, D2S1473, IL1R, IL1RA" ENSG00000115594 "Interleukin 1 receptor type 1" P14778 2 102064544-102179874 "Cancer-related genes, CD markers, Enzymes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Hydrolase, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 127.1;Endometrial stromal cells: 280.2;Glandular and luminal cells: 315.4;Hepatic stellate cells: 146.7;Langerhans cells: 188.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 624.9;ASC TERT1: 276.8;HHSteC: 196.3;HSkMC: 770.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001237, HPA005823, CAB007779, HPA029560" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" "Secreted to blood" NA NA 1400000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Vesicles" "Plasma membrane, Cytosol" "CAB007779: AB_562073, HPA001237: , HPA005823: AB_2667445, HPA029560: AB_2673094" "unprognostic (6.16e-3)" "unprognostic (3.55e-2)" "unprognostic (3.33e-1)" "unprognostic (1.22e-1)" "unprognostic (4.26e-2)" "unprognostic (7.10e-2)" "unprognostic (2.01e-1)" "unprognostic (3.36e-2)" "unprognostic (1.44e-1)" "unprognostic (3.16e-1)" "unprognostic (4.26e-2)" "unprognostic (7.77e-2)" "prognostic unfavorable (6.92e-6)" "unprognostic (2.48e-2)" "unprognostic (6.95e-2)" "unprognostic (4.83e-2)" "unprognostic (7.73e-2)" 137.3 68.0 7.1 69.5 8.3 18.0 77.5 7.5 11.0 161.1 16.2 39.3 20.7 33.5 105.2 32.1 52.0 92.0 58.3 7.6 9.0 45.7 75.5 115.5 17.1 16.2 8.4 31.1 43.3 126.7 13.1 120.8 8.9 66.7 30.5 8.5 34.2 47.4 18.6 40.1 40.3 49.9 10.0 41.0 43.9 20.6 14.9 21.7 52.5 16.0 19.7 87.4 40.2 7.7 2.0 12.8 0.3 10.8 624.9 276.8 4.4 27.4 123.8 19.2 28.7 5.7 3.4 0.0 19.8 55.0 33.9 5.5 0.2 2.2 16.1 55.5 0.1 0.7 2.9 31.3 196.3 0.1 0.3 770.6 2.3 21.7 5.2 8.4 8.7 0.0 3.5 1.1 28.1 5.6 0.0 1.2 0.7 5.6 0.9 0.3 2.0 0.4 18.3 13.4 0.1 0.3 12.5 7.7 0.0 3.6 11.1 0.8 0.3 54.7 3.6 92.1 2.2 0.1 0.0 0.1 21.3 0.6 3.6 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.2 0.2 0.0 0.0 0.6 0.0 7.1 8.3 7.5 11.0 7.6 9.0 16.2 8.4 8.9 10.0 14.9 7.7 99.3 25.6 73.2 1.3 1.8 31.1 46.8 8.2 5.2 0.1 19.4 13.7 5.2 28.6 68.6 5.5 0.0 6.1 2.5 0.7 3.9 31.7 7.0 127.1 280.2 103.6 1.2 14.3 0.5 21.8 82.8 79.1 2.0 315.4 1.3 0.3 146.7 47.1 5.4 0.0 3.0 0.5 10.2 12.0 188.2 12.6 28.0 26.0 19.6 23.4 7.0 9.0 0.0 0.5 0.5 12.0 0.3 1.5 1.8 65.9 0.0 8.3 28.6 1.0 6.6 37.7 34.3 1.3 1.2 4.5 38.6 23.9 8.5 4.0 0.8 23.6 INCENP FLJ31633 ENSG00000149503 "Inner centromere protein" Q9NQS7 11 62123998-62153169 "Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.9" "Cell type enhanced" "Detected in many" "Squamous epithelial cells: 15.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 7 "basophil: 1.2;NK-cell: 1.1" "Group enriched" "Detected in many" 7 "granulocytes: 1.2;NK-cells: 1.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013292, HPA051339, HPA070550" Enhanced Supported "Nucleoplasm,Nuclear bodies,Kinetochore,Midbody" Yes Yes "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear bodies, Kinetochore" "Nucleoplasm, Midbody" "CAB013292: AB_2533405, HPA051339: AB_2732566, HPA070550: AB_2686279" "unprognostic (6.31e-2)" "unprognostic (7.29e-2)" "unprognostic (1.65e-3)" "unprognostic (7.35e-2)" "unprognostic (3.18e-1)" "unprognostic (1.91e-1)" "prognostic unfavorable (1.25e-4)" "prognostic unfavorable (8.58e-4)" "unprognostic (1.63e-2)" "unprognostic (4.37e-2)" "prognostic unfavorable (5.76e-5)" "unprognostic (1.74e-2)" "unprognostic (1.08e-3)" "unprognostic (1.17e-3)" "unprognostic (1.22e-1)" "unprognostic (1.36e-1)" "unprognostic (2.78e-3)" 3.1 2.5 2.7 7.5 1.1 20.9 2.8 6.2 3.0 4.6 0.0 4.8 6.8 3.0 8.1 14.0 3.5 2.2 2.8 2.9 0.5 2.4 1.9 3.0 11.6 1.6 0.8 3.8 3.1 3.1 1.5 4.1 1.3 2.5 3.6 3.4 6.1 2.9 4.2 7.9 5.7 3.4 0.1 5.5 4.5 6.4 0.5 17.8 5.1 3.4 8.2 2.8 5.5 1.2 74.3 69.4 51.6 45.5 6.8 8.4 28.1 47.6 21.2 44.4 28.3 37.0 50.7 70.0 36.2 16.0 46.2 72.6 52.2 28.4 31.8 60.5 36.6 45.7 68.0 29.6 2.7 53.5 62.1 4.3 6.5 41.3 23.6 6.8 25.8 50.2 48.8 57.6 25.3 59.7 85.0 43.3 56.2 28.0 34.4 79.3 66.4 53.4 12.0 35.8 40.1 42.2 46.8 30.8 27.9 19.8 48.2 19.4 28.5 41.8 51.9 59.8 50.0 29.7 48.3 75.8 23.5 34.7 50.6 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 2.7 1.1 6.2 3.0 2.9 0.5 1.6 0.8 1.3 0.1 0.5 1.2 1.2 3.2 2.3 1.3 3.4 5.6 0.8 1.0 2.8 2.4 1.1 0.6 1.3 0.0 3.7 0.0 0.0 4.2 4.2 5.4 0.0 1.9 1.0 2.0 2.1 1.5 0.0 10.9 3.3 2.5 7.1 1.9 9.2 2.7 3.8 5.7 0.0 0.7 4.2 0.0 2.5 3.4 0.0 0.9 1.6 0.5 2.8 3.3 3.6 1.0 5.0 1.5 3.1 2.0 1.5 2.2 1.6 1.5 10.9 1.2 1.3 0.3 2.6 2.3 0.0 1.9 4.3 6.5 7.8 15.1 3.3 2.2 3.7 1.9 4.8 1.1 INTS12 "INT12, PHF22, SBBI22" ENSG00000138785 "Integrator complex subunit 12" Q96CB8 4 105682627-105895986 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035772, HPA041814" Approved Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" "Nuclear bodies, Plasma membrane" "HPA035772: AB_10671109, HPA041814: AB_2677687" "unprognostic (5.30e-2)" "unprognostic (4.54e-2)" "unprognostic (1.84e-3)" "unprognostic (1.78e-1)" "unprognostic (3.68e-2)" "unprognostic (2.58e-3)" "prognostic unfavorable (2.67e-4)" "unprognostic (3.95e-2)" "unprognostic (1.13e-1)" "unprognostic (1.53e-3)" "unprognostic (3.00e-2)" "unprognostic (3.48e-2)" "unprognostic (5.93e-3)" "unprognostic (3.62e-1)" "unprognostic (1.37e-1)" "unprognostic (2.16e-2)" "unprognostic (2.06e-1)" 15.2 11.1 12.8 10.9 13.3 30.4 20.2 14.9 18.0 14.1 12.0 14.7 18.1 14.6 17.8 13.5 13.2 12.7 18.9 12.4 14.9 18.7 22.6 16.4 14.0 12.3 14.0 11.6 12.6 17.2 10.3 11.9 12.5 18.1 15.6 17.2 14.4 13.4 26.5 14.0 15.5 17.1 12.7 12.6 15.0 13.9 14.3 19.9 19.9 26.0 17.0 15.6 11.2 13.7 24.4 12.8 28.5 29.8 27.5 32.6 20.8 28.2 29.1 34.7 35.9 18.1 26.9 34.9 15.4 31.9 26.9 13.8 31.7 40.7 42.8 36.9 19.0 26.3 19.6 25.7 44.3 46.7 23.0 31.0 51.7 34.5 51.4 22.5 32.3 29.1 39.8 26.7 37.8 25.6 55.3 28.9 12.4 35.3 19.5 28.0 31.0 26.8 32.5 16.3 30.7 24.6 19.8 32.6 31.0 22.4 26.4 27.2 21.3 22.7 23.3 24.8 30.5 40.8 40.9 52.2 25.3 31.5 46.0 64.0 23.7 38.5 25.7 26.6 28.9 33.0 29.4 29.4 27.7 32.1 30.6 28.3 17.9 42.9 28.3 42.6 34.8 21.9 12.8 13.3 14.9 18.0 12.4 14.9 12.3 14.0 12.5 12.7 14.3 13.7 19.0 12.8 11.8 14.0 15.1 11.0 11.8 25.8 15.4 10.5 12.1 11.7 18.7 11.5 12.9 3.7 10.4 16.1 13.6 8.3 43.0 25.2 35.8 8.1 11.2 16.8 6.0 15.6 13.8 20.3 18.6 10.8 8.6 8.7 24.7 9.9 11.7 9.3 17.8 10.1 15.7 5.2 30.5 9.0 9.5 28.4 12.2 9.8 7.2 9.4 15.5 14.0 21.6 27.2 19.1 20.5 6.8 8.2 18.9 14.2 16.5 17.1 6.2 9.3 0.0 12.9 20.1 13.4 16.2 14.1 10.4 18.3 13.0 14.9 10.2 11.0 INTS14 "C15orf44, DKFZP564O1664, VWA9" ENSG00000138614 "Integrator complex subunit 14" Q96SY0 15 65578753-65611289 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 40.5;Extravillous trophoblasts: 30.5;Syncytiotrophoblasts: 49.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040255, HPA040651" Approved Approved "Nucleoplasm,Nuclear membrane,Nuclear bodies,Mitochondria" No No "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Nuclear bodies, Mitochondria" "Nuclear membrane" "HPA040255: AB_10805710, HPA040651: AB_10796559" "unprognostic (2.92e-1)" "unprognostic (3.01e-1)" "unprognostic (2.78e-1)" "unprognostic (2.41e-1)" "unprognostic (4.06e-1)" "unprognostic (2.35e-2)" "unprognostic (1.36e-1)" "unprognostic (1.63e-1)" "unprognostic (5.80e-2)" "unprognostic (5.60e-2)" "unprognostic (2.57e-2)" "unprognostic (2.67e-2)" "unprognostic (1.03e-3)" "unprognostic (1.92e-2)" "unprognostic (1.23e-1)" "unprognostic (5.75e-2)" "unprognostic (1.30e-1)" 12.5 15.8 13.2 14.2 15.8 18.0 22.3 14.7 16.6 20.9 18.2 21.8 14.1 18.1 27.4 16.1 24.2 19.6 13.4 13.5 14.8 21.3 21.1 15.6 22.7 14.5 14.9 18.4 17.7 22.9 16.3 19.2 14.6 19.1 23.6 13.1 16.2 19.8 9.9 18.0 17.2 18.8 14.8 18.9 18.1 18.9 15.8 25.4 23.2 13.6 24.3 23.6 13.6 17.7 26.4 46.7 46.1 36.8 25.2 31.4 29.5 28.4 36.5 46.4 42.5 42.2 61.2 42.9 38.9 35.6 38.5 52.0 99.4 47.6 40.5 37.8 60.2 37.5 32.2 46.4 50.0 38.7 46.2 30.6 46.9 35.1 53.7 34.1 50.8 64.8 52.2 24.3 33.4 41.7 44.3 41.2 33.8 66.2 25.6 37.5 38.8 49.0 36.7 48.6 33.1 26.3 34.2 34.5 49.5 39.2 32.3 44.0 25.2 31.8 33.2 28.8 45.6 23.9 48.4 58.1 32.1 70.0 38.1 25.7 11.0 6.2 19.8 12.7 22.3 19.3 20.3 22.6 19.8 14.8 21.1 19.2 1.2 23.8 9.5 17.9 30.8 16.6 13.2 15.8 14.7 16.6 13.5 14.8 14.5 14.9 14.6 14.8 15.8 17.7 12.2 22.4 10.9 0.0 3.8 0.0 0.0 0.0 0.0 0.0 13.0 11.0 0.0 0.0 5.6 12.9 0.0 40.5 7.7 0.0 21.5 18.2 0.0 12.8 11.8 6.8 0.0 0.0 0.0 15.4 30.5 6.7 0.0 12.6 7.6 22.5 0.0 0.0 16.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 9.3 0.0 0.0 0.0 0.0 16.6 0.0 0.0 0.5 0.0 0.0 15.1 10.9 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 49.8 4.8 24.0 0.0 0.0 IQUB FLJ35834 ENSG00000164675 "IQ motif and ubiquitin domain containing" Q8NA54 7 123452193-123535077 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 33.4" "Group enriched" "Detected in many" 7 "Early spermatids: 283.9;Endometrial ciliated cells: 82.6;Late spermatids: 157.5;Respiratory ciliated cells: 88.2;Spermatocytes: 116.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RPTEC TERT1: 2.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA049626 Approved "Nucleoplasm,Nuclear speckles,Intermediate filaments,Cytosol" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" "Nuclear speckles" "Nucleoplasm, Intermediate filaments, Cytosol" "HPA049626: AB_2732554" "unprognostic (8.71e-2)" "unprognostic (1.25e-2)" "unprognostic (1.98e-1)" "unprognostic (6.42e-4)" "unprognostic (1.91e-1)" "unprognostic (1.44e-2)" "unprognostic (6.23e-2)" "unprognostic (7.97e-2)" "unprognostic (1.46e-1)" "unprognostic (1.73e-1)" "unprognostic (2.40e-2)" "unprognostic (3.76e-1)" "unprognostic (5.44e-6)" "unprognostic (2.79e-1)" "unprognostic (9.78e-3)" "unprognostic (2.14e-1)" "unprognostic (7.30e-2)" 0.1 0.6 0.2 0.0 0.4 0.0 0.5 1.7 0.9 0.8 3.9 0.1 0.0 0.7 1.1 0.0 5.0 0.8 0.1 0.2 0.5 3.0 0.0 0.8 0.0 1.8 2.0 0.2 0.3 1.7 1.0 0.1 1.3 0.5 0.0 1.1 0.2 0.6 0.1 0.1 0.0 0.2 1.0 0.0 0.1 33.4 0.6 0.0 3.0 0.1 0.0 0.1 0.1 0.4 0.1 0.0 0.4 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.5 0.3 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 1.7 0.9 0.2 0.5 1.8 2.0 1.3 1.0 0.6 0.4 1.1 6.4 0.5 19.6 0.0 0.5 0.7 3.8 0.0 2.5 1.9 1.8 1.8 0.0 11.4 18.4 4.2 0.4 0.1 0.1 1.9 1.1 283.9 82.6 3.2 0.9 1.8 0.0 12.0 0.4 0.3 1.1 0.0 1.7 1.3 0.3 0.7 0.0 0.1 3.3 8.6 0.2 8.2 0.0 0.3 157.5 2.5 0.4 0.0 4.7 0.3 1.8 0.0 5.0 2.6 0.2 0.0 3.0 0.0 0.5 0.0 5.7 88.2 9.0 6.6 0.7 2.7 116.2 6.0 0.2 0.1 0.7 0.3 2.9 0.0 0.3 ITGA9 "ALPHA-RLC, ITGA4L, RLC" ENSG00000144668 "Integrin subunit alpha 9" Q13797 3 37452115-37823507 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 82.0;Hepatic stellate cells: 54.3;Inhibitory neurons: 61.0;Leydig cells: 41.3;Microglial cells: 53.4;Oligodendrocyte precursor cells: 93.5;Peritubular cells: 74.9" "Cancer enriched" "Detected in all" 5 "thyroid cancer: 23.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 10.1;HEL: 8.1;SH-SY5Y: 11.8;SuSa: 16.9;WM-115: 6.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030609 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" "Intracellular and membrane" NA NA 500000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "Nucleoplasm, Plasma membrane, Cell Junctions" "HPA030609: AB_10600815" "unprognostic (2.35e-2)" "unprognostic (3.36e-2)" "unprognostic (5.58e-2)" "unprognostic (3.94e-2)" "unprognostic (4.48e-2)" "unprognostic (2.85e-2)" "unprognostic (3.10e-1)" "unprognostic (8.87e-3)" "unprognostic (3.23e-1)" "unprognostic (2.31e-1)" "unprognostic (2.04e-1)" "unprognostic (1.51e-1)" "unprognostic (1.78e-2)" "unprognostic (1.50e-2)" "unprognostic (1.07e-1)" "unprognostic (1.72e-2)" "unprognostic (3.16e-2)" 8.8 15.5 1.9 4.5 1.8 8.5 5.9 0.0 6.2 21.8 3.6 9.6 6.3 10.6 4.0 15.5 5.4 9.4 20.1 7.8 0.7 4.0 14.8 8.9 4.1 0.9 1.3 5.0 1.8 2.6 1.7 9.8 0.4 12.5 6.8 0.7 4.2 10.8 2.8 3.0 9.1 15.8 0.7 22.6 7.5 6.9 5.0 1.8 20.7 9.8 2.4 6.5 4.5 1.2 0.2 0.0 4.3 0.3 0.0 0.2 0.1 0.1 0.0 0.0 0.0 10.1 0.0 3.2 1.4 0.0 0.1 0.2 3.8 0.0 0.0 0.1 0.6 8.1 0.1 0.2 0.2 0.0 4.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.2 0.0 0.0 0.0 0.0 3.0 0.1 0.0 0.0 0.4 0.3 0.0 0.2 0.5 11.8 0.1 0.5 0.7 16.9 0.0 3.1 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.1 0.2 6.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.8 0.0 6.2 7.8 0.7 0.9 1.3 0.4 0.7 5.0 1.2 20.8 0.0 14.7 16.0 0.1 2.5 1.1 0.1 1.2 1.2 1.1 2.9 12.9 2.8 3.1 1.8 0.0 0.2 0.0 0.0 0.0 0.1 1.5 1.4 4.9 21.6 0.0 3.0 82.0 0.0 0.5 7.5 0.0 0.9 6.3 36.2 54.3 1.3 2.8 0.0 61.0 0.1 0.0 31.9 2.2 4.2 41.3 5.7 3.6 53.4 0.1 0.6 0.0 93.5 6.2 0.0 0.0 74.9 0.4 0.2 0.0 0.1 0.0 0.0 0.0 3.2 3.3 0.6 0.9 0.0 1.7 0.3 1.8 25.9 0.4 0.3 KATNBL1 "C15orf29, FLJ22557" ENSG00000134152 "Katanin regulatory subunit B1 like 1" Q9H079 15 34140674-34210096 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 128.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 128.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062573 Approved Supported "Nucleoplasm,Midbody,Cleavage furrow,Mitotic spindle" Yes No "Cluster 9: Neutrophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Midbody, Mitotic spindle" "Nucleoplasm, Cleavage furrow" "HPA062573: AB_2684796" "unprognostic (5.02e-1)" "unprognostic (1.67e-1)" "unprognostic (1.35e-2)" "unprognostic (2.91e-2)" "unprognostic (2.01e-2)" "unprognostic (1.38e-1)" "unprognostic (1.14e-1)" "unprognostic (1.75e-1)" "unprognostic (1.01e-1)" "unprognostic (5.16e-2)" "unprognostic (3.94e-3)" "unprognostic (8.00e-3)" "prognostic unfavorable (4.60e-5)" "unprognostic (2.71e-2)" "unprognostic (7.23e-2)" "unprognostic (2.42e-1)" "unprognostic (1.43e-1)" 22.0 12.1 16.3 22.9 16.6 16.3 20.8 25.0 20.8 22.5 22.4 19.9 15.9 20.7 19.0 39.9 16.8 15.9 13.4 15.8 14.9 17.0 17.6 18.4 17.6 15.0 13.8 14.4 14.0 14.5 12.1 32.4 16.0 16.9 21.2 31.2 14.6 13.6 13.2 31.4 15.7 25.4 12.9 18.6 17.7 18.0 18.2 15.2 12.5 13.0 20.3 17.8 27.7 25.3 37.1 31.5 49.7 33.4 39.5 39.0 37.0 49.6 30.0 38.7 38.4 17.8 19.9 17.6 31.2 32.2 54.5 47.5 24.9 28.5 45.8 36.9 12.6 31.8 34.6 21.6 27.0 33.9 33.1 23.6 40.8 26.1 51.3 39.7 70.6 45.4 34.3 36.7 53.1 17.6 21.4 27.4 35.8 47.4 25.0 32.3 30.3 16.1 35.9 49.5 28.1 24.8 30.1 21.9 14.7 49.2 27.0 38.8 40.4 51.9 26.7 46.8 39.7 21.5 32.5 37.1 46.5 35.7 38.9 62.8 18.2 29.7 18.4 17.3 23.3 23.9 19.6 18.8 20.7 25.6 21.5 19.2 128.5 13.2 11.5 28.4 17.9 12.0 16.3 16.6 25.0 20.8 15.8 14.9 15.0 13.8 16.0 12.9 18.2 25.3 59.7 38.5 25.2 83.9 41.7 41.3 65.2 60.5 34.7 57.0 42.1 43.1 12.8 24.3 51.6 25.8 52.1 58.6 42.3 30.6 33.2 59.1 75.4 40.5 53.3 47.0 23.9 39.8 104.3 54.5 86.2 38.8 39.3 50.8 44.9 68.7 37.9 20.8 39.1 67.3 96.7 35.6 52.9 27.6 48.8 59.2 31.7 36.2 32.0 64.6 49.9 53.1 27.8 86.0 114.4 105.3 37.4 33.1 41.1 116.8 21.4 41.6 49.6 44.7 59.2 52.2 45.3 47.8 44.3 45.0 54.3 179.5 39.7 31.6 39.1 132.6 KCNC1 Kv3.1 ENSG00000129159 "Potassium voltage-gated channel subfamily C member 1" P48547 11 17734774-17856804 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 47.3" "Group enriched" "Detected in some" 5 "Bipolar cells: 79.6;Excitatory neurons: 48.2;Inhibitory neurons: 120.2" "Group enriched" "Detected in some" 5 "glioma: 1.1;testis cancer: 0.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 3.2;neutrophil: 1.4" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.2" "Cell line enhanced" "Detected in some" "HeLa: 1.6;RH-30: 3.7;SCLC-21H: 3.5;SH-SY5Y: 2.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047634, HPA048249" Enhanced Approved "Nucleoplasm,Nuclear membrane,Vesicles,Cytosol" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 6: Brain - Smell perception" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Nuclear membrane" "Vesicles, Cytosol" "HPA047634: AB_2680109, HPA048249: " "unprognostic (1.79e-2)" "unprognostic (2.68e-1)" "unprognostic (1.33e-1)" "unprognostic (4.09e-3)" "unprognostic (1.12e-1)" "unprognostic (8.02e-2)" "unprognostic (2.40e-1)" "unprognostic (1.27e-1)" "unprognostic (8.37e-2)" "unprognostic (2.14e-1)" "unprognostic (7.04e-5)" "unprognostic (5.89e-2)" "unprognostic (7.32e-4)" "unprognostic (1.29e-1)" "unprognostic (5.44e-2)" "unprognostic (1.05e-2)" "unprognostic (7.83e-2)" 0.1 0.8 1.1 0.1 3.3 0.9 0.2 41.0 47.3 0.9 0.0 0.3 0.3 0.3 0.0 0.2 0.1 0.2 0.1 4.5 8.0 0.1 0.2 0.1 0.2 8.8 3.0 0.2 0.4 0.0 2.2 0.0 9.3 0.2 0.0 7.0 0.3 0.0 0.5 0.5 0.3 0.0 1.0 0.2 0.3 1.4 12.3 0.1 0.3 1.2 0.0 0.3 0.5 18.8 0.1 0.0 1.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.4 0.9 0.0 0.1 0.2 1.1 0.3 1.6 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.7 0.0 0.2 0.2 0.4 0.7 0.0 0.0 0.4 3.7 0.4 0.0 0.2 3.5 2.1 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 1.0 0.1 0.0 0.2 0.3 0.4 0.2 0.2 0.4 3.2 0.3 0.4 0.3 0.2 0.2 0.2 0.3 0.2 0.0 0.5 0.2 0.2 1.4 0.2 0.3 0.3 0.1 0.1 1.1 3.3 41.0 47.3 4.5 8.0 8.8 3.0 9.3 1.0 12.3 18.8 0.2 0.0 0.0 5.5 1.1 0.0 0.2 0.0 0.0 79.6 0.3 0.4 2.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.5 9.5 0.2 0.5 0.4 7.7 0.0 48.2 0.2 0.0 0.3 0.0 0.3 0.0 2.8 0.0 0.0 0.0 1.7 120.2 0.0 0.0 0.0 0.0 10.2 0.3 0.2 0.0 7.5 0.6 1.5 0.0 16.1 5.6 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 7.7 0.0 0.2 0.5 6.1 5.0 0.0 0.0 0.0 0.6 1.8 0.0 0.0 KCTD1 C18orf5 ENSG00000134504 "Potassium channel tetramerization domain containing 1" Q719H9 18 26454910-26657401 "Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 106.4;Distal tubular cells: 117.4;Excitatory neurons: 283.7;Squamous epithelial cells: 109.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 106.6;HaCaT: 113.5;hTCEpi: 100.6;RPTEC TERT1: 97.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057808, HPA062486" Approved "Nucleoplasm,Nucleoli,Cytokinetic bridge,Centriolar satellite" Yes NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Nucleoli, Cytokinetic bridge, Centriolar satellite" "HPA057808: , HPA062486: " "unprognostic (1.15e-3)" "unprognostic (5.66e-2)" "unprognostic (2.35e-4)" "prognostic unfavorable (2.22e-4)" "unprognostic (3.65e-3)" "unprognostic (7.43e-2)" "unprognostic (2.03e-3)" "unprognostic (6.77e-2)" "unprognostic (2.74e-1)" "unprognostic (1.88e-3)" "unprognostic (5.68e-3)" "unprognostic (1.77e-2)" "prognostic favorable (4.60e-8)" "unprognostic (3.87e-3)" "unprognostic (7.39e-2)" "unprognostic (1.50e-1)" "unprognostic (8.02e-2)" 7.8 16.5 21.7 2.7 41.5 0.6 32.4 14.0 44.3 19.2 9.5 9.7 4.1 14.2 22.6 50.6 50.2 8.4 23.8 31.2 10.3 28.8 3.5 5.5 2.7 9.8 13.6 15.1 7.4 12.0 10.8 11.4 9.2 21.6 10.6 18.4 19.9 22.6 5.1 61.1 3.7 12.5 10.2 3.9 10.3 5.9 13.7 17.6 19.9 6.9 14.3 13.0 36.9 29.6 17.5 55.1 106.6 11.6 61.8 9.7 13.4 14.3 21.5 22.0 21.9 5.1 19.1 2.9 52.2 30.5 18.0 113.5 20.5 30.6 20.6 2.2 8.7 3.1 10.2 8.2 11.1 1.7 4.7 16.7 100.6 6.2 41.4 28.0 21.0 24.1 1.3 1.2 16.0 24.5 16.3 5.2 10.5 57.1 27.1 8.5 5.7 2.3 97.8 25.2 10.3 40.5 20.7 27.5 8.7 61.3 24.1 4.0 11.7 24.4 6.8 4.8 15.0 4.8 4.1 0.4 8.7 11.0 36.8 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.7 41.5 14.0 44.3 31.2 10.3 9.8 13.6 9.2 10.2 13.7 29.6 3.0 3.2 4.1 80.0 0.7 31.7 55.9 17.2 106.4 5.0 27.3 29.7 13.9 8.6 15.0 25.8 8.4 45.5 0.8 6.2 117.4 8.3 28.0 47.0 7.8 2.9 1.2 0.8 283.7 3.6 7.6 5.5 7.1 42.4 0.0 66.3 2.5 1.7 4.4 21.9 66.1 4.3 20.3 0.8 1.7 12.0 5.3 1.2 23.2 16.9 0.4 21.4 1.0 81.4 42.1 11.8 2.4 3.0 6.6 36.4 0.4 10.7 29.3 5.9 0.0 2.7 6.2 1.8 5.1 109.0 44.5 33.2 1.0 6.3 4.0 51.2 KEL "CD238, ECE3" ENSG00000197993 "Kell metallo-endopeptidase (Kell blood group)" P23276 7 142941114-142962363 "Blood group antigen proteins, Cancer-related genes, CD markers, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Blood group antigen, Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 56.3;testis: 32.3" "Cell type enhanced" "Detected in some" "Erythroid cells: 79.7;Oligodendrocytes: 30.1;Squamous epithelial cells: 16.8" "Cancer enhanced" "Detected in some" "testis cancer: 2.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 20 "HEL: 31.7;K-562: 26.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA064442 Approved "Nucleoplasm,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" "Golgi apparatus, Plasma membrane" "Nucleoplasm, Cytosol" "HPA064442: " "unprognostic (5.78e-3)" "unprognostic (1.08e-5)" "unprognostic (5.29e-3)" "unprognostic (4.85e-3)" "unprognostic (9.68e-2)" "unprognostic (1.96e-2)" "unprognostic (1.03e-1)" "unprognostic (1.54e-2)" "unprognostic (5.18e-2)" "unprognostic (1.08e-2)" "unprognostic (3.71e-2)" "unprognostic (3.57e-2)" "unprognostic (2.29e-3)" "unprognostic (9.24e-2)" "unprognostic (7.05e-2)" "unprognostic (3.32e-2)" "unprognostic (3.25e-3)" 0.2 0.0 1.8 0.8 2.7 56.3 0.3 1.7 2.2 0.9 1.4 0.1 0.0 0.2 0.0 0.8 0.5 0.0 0.3 2.0 1.5 0.6 0.3 0.5 10.6 2.5 2.2 0.2 0.2 0.0 0.2 0.4 2.4 0.3 0.0 0.1 0.6 0.1 0.2 0.1 0.9 0.0 1.9 4.9 0.2 32.3 2.4 1.3 0.3 0.0 6.7 0.1 0.4 2.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 31.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.2 0.0 0.0 0.1 0.5 0.1 0.6 0.0 0.0 0.1 0.0 0.2 0.0 1.4 0.0 0.2 0.0 0.0 0.3 0.4 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 2.7 1.7 2.2 2.0 1.5 2.5 2.2 2.4 1.9 2.4 2.8 0.2 0.0 0.0 0.3 0.0 0.0 1.3 0.2 4.0 0.0 0.3 0.1 0.4 0.0 1.4 3.7 0.0 0.1 0.1 0.0 1.9 0.3 2.4 0.2 0.1 0.1 0.0 79.7 3.0 0.0 0.2 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.9 0.0 0.5 0.0 0.0 0.0 0.0 0.8 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 30.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 3.1 0.0 1.4 0.2 16.8 0.0 0.1 0.0 0.0 0.0 0.9 KIAA0895 ENSG00000164542 KIAA0895 Q8NCT3 7 36324152-36390125 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 22.3" "Cell type enhanced" "Detected in many" "Early spermatids: 87.9;Endometrial ciliated cells: 41.8;Late spermatids: 65.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 38.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021036, HPA061066" Uncertain Approved "Nucleoplasm,Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "Plasma membrane, Cell Junctions, Cytosol" "HPA021036: AB_2670571, HPA061066: AB_2684423" "unprognostic (4.94e-2)" "unprognostic (9.59e-2)" "unprognostic (2.93e-1)" "unprognostic (1.39e-1)" "unprognostic (8.85e-2)" "unprognostic (1.15e-3)" "unprognostic (3.79e-3)" "unprognostic (3.43e-1)" "unprognostic (3.74e-1)" "unprognostic (4.71e-3)" "unprognostic (1.46e-1)" "unprognostic (3.49e-1)" "unprognostic (4.51e-2)" "unprognostic (6.68e-2)" "unprognostic (3.06e-2)" "unprognostic (2.35e-2)" "unprognostic (5.24e-2)" 1.1 8.1 5.3 0.7 5.8 2.4 3.7 14.2 5.2 2.3 10.5 2.5 1.8 3.0 6.2 2.3 5.8 3.1 1.7 5.3 8.7 9.2 5.5 3.0 0.2 4.1 5.0 8.6 9.1 11.6 6.3 1.2 3.9 2.9 1.3 15.0 2.8 2.6 1.5 5.8 1.1 2.9 3.7 0.6 11.1 22.3 6.0 3.2 3.6 1.4 0.4 1.3 1.1 5.0 10.7 6.3 13.2 12.4 0.4 0.3 2.9 2.8 3.3 6.5 7.5 2.8 5.5 0.1 3.0 0.7 11.0 6.1 18.1 5.6 5.4 0.9 10.1 0.2 9.7 2.5 2.3 1.9 0.4 1.5 9.5 6.0 7.0 7.7 0.2 5.8 4.4 0.2 0.6 3.8 6.0 4.0 0.6 2.6 1.5 2.2 0.5 0.0 13.8 1.3 38.1 13.6 4.8 12.5 4.0 9.0 11.8 1.5 0.0 0.8 3.2 1.8 4.2 6.2 14.6 0.1 2.4 0.5 2.8 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 5.3 5.8 14.2 5.2 5.3 8.7 4.1 5.0 3.9 3.7 6.0 5.0 1.5 6.4 2.7 7.5 1.4 9.7 5.1 3.5 17.6 17.8 13.3 8.1 3.7 5.7 3.7 3.7 27.1 2.3 0.9 0.9 5.9 5.0 87.9 41.8 2.2 1.6 8.4 0.8 22.4 2.9 1.2 2.1 11.2 13.3 1.3 8.3 0.4 5.6 0.5 11.8 25.9 1.5 0.0 0.0 0.4 65.4 2.8 0.4 3.6 1.0 0.1 5.7 0.0 12.1 13.1 3.9 1.7 0.4 3.2 3.0 0.2 10.0 25.9 16.3 6.6 5.7 2.1 28.8 11.9 4.7 8.7 0.7 1.2 7.6 1.6 2.0 KIF18B ENSG00000186185 "Kinesin family member 18B" Q86Y91 17 44924709-44947773 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 12.7;lymphoid tissue: 14.4" "Cell type enhanced" "Detected in some" "Erythroid cells: 9.0;Extravillous trophoblasts: 3.8;Granulosa cells: 5.9;Oligodendrocyte precursor cells: 7.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in single" "white matter: 1.4" "Low region specificity" "Detected in many" HPA024205 Enhanced Supported "Nucleoplasm,Nuclear bodies,Microtubule ends,Cytosol" Yes Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Microtubule ends" "Nuclear bodies, Cytosol" "HPA024205: AB_1852472" "unprognostic (1.88e-1)" "unprognostic (9.92e-2)" "unprognostic (4.61e-2)" "unprognostic (1.13e-2)" "unprognostic (4.17e-1)" "unprognostic (7.27e-3)" "prognostic unfavorable (2.44e-6)" "unprognostic (3.34e-3)" "prognostic unfavorable (6.90e-4)" "unprognostic (1.98e-1)" "prognostic unfavorable (2.16e-4)" "unprognostic (8.18e-2)" "unprognostic (0.00e+0)" "unprognostic (4.69e-3)" "unprognostic (1.93e-1)" "unprognostic (3.08e-1)" "unprognostic (1.68e-2)" 0.4 0.4 0.3 3.8 0.4 12.7 0.2 0.7 0.3 0.9 0.3 2.0 2.7 0.4 0.0 5.1 0.2 0.4 0.3 0.3 0.4 0.2 0.4 0.8 5.7 0.5 1.1 0.1 0.1 0.0 0.1 1.9 0.6 0.2 1.7 0.1 0.7 0.0 0.4 3.0 2.5 1.1 0.3 2.9 1.5 2.9 0.6 14.4 0.2 0.0 4.7 0.6 1.6 0.5 31.5 41.7 35.3 32.8 0.8 3.0 28.1 25.8 10.3 34.6 26.9 34.0 27.4 28.3 10.9 10.8 21.5 34.0 25.1 11.3 17.9 56.6 36.4 35.4 51.7 22.1 0.0 30.0 30.2 0.7 0.6 29.7 12.2 4.7 17.9 29.2 28.1 48.0 18.2 25.9 60.0 31.1 25.4 30.4 28.9 43.5 51.8 19.2 5.8 16.7 26.2 24.7 18.0 16.1 9.8 17.0 30.2 21.6 11.2 49.9 48.0 28.8 56.8 15.1 15.7 34.4 16.3 22.9 33.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.3 0.4 0.7 0.3 0.3 0.4 0.5 1.1 0.6 0.3 0.6 0.5 0.1 0.0 0.0 0.0 0.9 0.4 0.1 0.2 0.0 0.5 0.5 0.4 2.6 0.0 0.0 0.0 0.0 2.4 0.4 1.9 0.0 0.0 0.0 0.3 0.8 0.6 0.0 9.0 0.3 0.0 3.8 1.4 1.5 0.5 0.0 5.9 0.4 0.3 2.3 0.0 0.3 1.6 0.0 2.2 1.1 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 7.1 0.1 0.1 0.0 0.0 2.1 0.2 0.3 0.0 0.0 0.3 0.0 0.2 0.8 1.1 2.9 2.5 0.4 0.8 1.3 0.3 3.2 0.3 KIF20B "CT90, KRMP1, MPHOSPH1, MPP1" ENSG00000138182 "Kinesin family member 20B" Q96Q89 10 89701590-89774939 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.2;lymphoid tissue: 9.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 89.2;Spermatocytes: 165.4;Spermatogonia: 96.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA050214 Supported Supported "Nucleoplasm,Cytokinetic bridge,Midbody,Cytosol" Yes Yes "Cluster 6: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytokinetic bridge" "Midbody, Cytosol" "HPA050214: AB_2681053" "unprognostic (2.13e-1)" "unprognostic (3.01e-2)" "unprognostic (1.72e-2)" "unprognostic (3.20e-2)" "unprognostic (2.65e-1)" "unprognostic (7.39e-2)" "unprognostic (8.95e-5)" "unprognostic (3.32e-3)" "unprognostic (2.01e-2)" "unprognostic (8.14e-2)" "prognostic unfavorable (1.21e-4)" "unprognostic (1.62e-2)" "prognostic unfavorable (3.06e-6)" "unprognostic (4.22e-3)" "unprognostic (2.70e-1)" "unprognostic (2.51e-2)" "unprognostic (6.43e-2)" 1.3 0.7 0.3 4.5 1.0 10.2 2.5 2.4 0.4 1.5 0.1 3.2 3.6 2.3 0.4 3.3 1.2 1.3 0.9 0.3 0.3 1.3 1.3 1.5 8.0 0.5 0.3 2.7 0.7 1.1 0.2 2.4 0.6 1.3 4.0 1.1 1.0 0.9 0.4 2.5 3.4 2.2 0.4 3.3 2.5 6.9 0.6 9.8 1.8 0.7 7.5 1.6 0.7 0.6 84.8 17.0 24.3 21.7 4.7 8.0 20.2 33.8 30.9 34.8 36.3 22.6 38.1 32.5 10.4 17.3 13.0 41.8 27.3 18.9 46.4 39.5 18.6 33.1 30.5 19.5 1.4 57.1 26.3 3.4 2.8 33.7 33.9 12.2 22.8 17.0 32.2 36.5 31.3 14.6 33.6 10.8 25.0 13.8 16.1 23.1 47.8 14.3 10.7 11.2 7.7 13.9 24.4 11.0 12.2 17.3 28.5 16.3 17.9 22.2 22.1 29.1 55.3 10.1 29.5 43.2 21.1 49.4 16.8 13.1 2.4 4.2 5.5 4.1 6.8 13.0 7.4 6.1 1.3 16.0 8.6 8.0 0.2 3.0 4.5 5.2 9.5 2.2 0.3 1.0 2.4 0.4 0.3 0.3 0.5 0.3 0.6 0.4 0.6 0.6 11.5 3.2 13.5 2.3 36.4 17.7 6.2 20.8 6.8 14.3 8.3 8.5 8.7 1.5 10.7 0.0 10.4 21.4 32.3 8.8 3.9 6.9 13.1 10.6 13.2 11.0 1.2 89.2 8.1 4.7 38.1 13.2 14.8 12.9 44.4 37.2 9.3 4.4 20.7 13.5 9.5 8.6 16.2 21.0 17.9 10.5 8.1 17.1 5.4 23.4 11.3 7.5 24.7 9.0 9.1 4.1 5.7 8.6 51.4 3.7 8.9 3.2 6.6 9.8 6.6 16.9 17.1 165.4 96.7 26.1 14.1 5.2 34.2 12.9 25.5 5.2 KLC2 FLJ12387 ENSG00000174996 "Kinesin light chain 2" Q9H0B6 11 66257294-66267860 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Motor protein" "Hereditary spastic paraplegia, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Horizontal cells: 55.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040416, HPA040434" Approved Supported "Nucleoplasm,Plasma membrane,Mitochondria,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane, Cytosol" "Nucleoplasm, Mitochondria" "HPA040416: AB_10795524, HPA040434: AB_10795367" "unprognostic (1.29e-1)" "unprognostic (4.95e-3)" "unprognostic (2.99e-1)" "unprognostic (3.24e-2)" "unprognostic (2.33e-1)" "prognostic unfavorable (3.16e-4)" "unprognostic (2.43e-3)" "unprognostic (2.45e-2)" "unprognostic (6.27e-3)" "unprognostic (1.60e-1)" "unprognostic (3.49e-2)" "unprognostic (1.64e-3)" "unprognostic (4.57e-3)" "unprognostic (1.96e-2)" "unprognostic (1.81e-1)" "unprognostic (1.72e-2)" "unprognostic (8.08e-2)" 15.2 18.0 18.8 9.5 25.4 3.6 15.9 33.0 78.1 27.3 0.0 28.5 9.8 27.1 6.3 18.2 21.6 8.9 32.1 26.6 12.7 22.4 8.2 18.9 9.1 39.8 10.8 24.6 15.5 15.2 48.3 7.2 37.0 28.7 4.7 28.4 15.9 16.0 57.8 18.3 16.3 11.2 5.7 13.7 20.2 32.2 23.1 25.1 17.7 14.2 6.4 27.2 21.7 35.8 49.4 58.2 28.3 16.9 16.9 13.5 21.9 34.1 24.2 34.2 26.1 31.9 14.3 21.3 31.9 25.6 43.9 40.7 29.3 33.2 11.4 35.7 37.2 4.4 48.0 22.4 32.1 9.9 22.7 13.5 42.7 40.1 32.8 22.0 16.1 26.2 24.1 29.0 27.8 69.2 56.8 15.0 27.8 14.2 49.2 21.4 14.6 30.1 27.2 27.4 76.3 37.5 24.6 22.1 41.3 15.7 36.3 6.7 26.8 55.5 49.8 68.2 45.5 30.7 27.4 11.9 39.3 6.7 22.9 0.0 0.2 0.5 2.4 0.1 3.1 1.9 1.1 1.6 0.3 3.2 1.1 1.4 0.3 1.3 0.2 2.1 0.3 1.1 18.8 25.4 33.0 78.1 26.6 12.7 39.8 10.8 37.0 5.7 23.1 35.8 4.0 3.2 1.5 8.8 8.9 8.9 9.2 11.1 7.4 34.4 10.1 7.2 2.4 7.2 5.5 12.9 12.5 9.9 5.1 3.1 13.7 14.8 10.1 7.7 6.2 5.2 37.1 0.8 20.7 8.2 18.2 6.5 13.7 9.7 0.0 8.6 3.9 2.3 3.1 55.5 19.0 7.2 18.3 3.2 4.0 4.6 8.7 2.8 12.4 5.6 6.3 14.6 4.1 4.0 6.2 19.1 4.9 13.9 9.1 18.2 3.9 10.3 7.3 35.2 0.0 9.5 13.3 26.2 29.8 8.9 9.7 12.7 8.2 3.4 4.9 8.5 KLF11 "MODY7, TIEG2, Tieg3" ENSG00000172059 "Kruppel like factor 11" O14901 2 10042849-10054836 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 135.0;Suprabasal keratinocytes: 86.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 47.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058276 Supported "Nucleoplasm,Nuclear bodies,Focal adhesion sites,Cytosol" Yes No "Cluster 7: Monocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "Nuclear bodies, Focal adhesion sites, Cytosol" "HPA058276: AB_2683664" "unprognostic (9.66e-3)" "unprognostic (1.87e-1)" "unprognostic (1.59e-1)" "unprognostic (1.06e-2)" "unprognostic (3.02e-3)" "unprognostic (2.63e-3)" "unprognostic (6.34e-2)" "unprognostic (1.04e-2)" "unprognostic (1.67e-1)" "unprognostic (1.04e-1)" "unprognostic (3.17e-3)" "unprognostic (3.08e-2)" "unprognostic (2.48e-3)" "unprognostic (8.96e-2)" "unprognostic (3.44e-1)" "unprognostic (1.07e-2)" "unprognostic (9.24e-2)" 27.7 15.6 4.0 7.6 3.2 27.8 22.3 8.3 3.9 13.5 4.1 17.9 7.5 20.0 9.7 13.2 13.7 18.1 19.1 2.9 3.9 15.7 35.2 22.4 9.3 3.7 3.3 23.9 54.2 18.3 2.5 19.5 3.4 10.1 9.3 3.0 15.9 14.8 12.1 26.9 8.7 16.8 3.2 18.8 12.4 30.0 3.5 4.0 16.5 27.3 5.5 12.6 13.1 5.1 6.9 3.3 7.8 0.7 5.3 9.4 18.8 7.9 7.9 4.4 4.6 7.8 15.8 0.0 13.9 9.6 17.9 1.6 6.8 6.1 2.9 47.6 5.2 3.5 9.7 1.6 5.2 14.6 22.1 14.7 22.3 8.4 2.3 11.4 3.9 1.3 9.7 30.8 4.6 8.2 0.0 2.7 12.5 5.6 6.7 7.8 0.2 13.6 10.8 8.5 10.0 6.2 12.0 24.5 23.4 12.2 5.7 19.6 11.2 19.3 15.9 14.7 2.6 27.9 36.0 18.7 5.0 3.8 10.4 0.0 8.2 2.0 2.6 12.3 0.8 3.2 1.8 1.9 7.3 2.9 0.5 1.1 0.2 6.6 14.8 0.3 3.0 5.4 4.0 3.2 8.3 3.9 2.9 3.9 3.7 3.3 3.4 3.2 3.5 5.1 58.8 6.4 4.6 0.3 12.5 60.5 17.7 5.5 25.6 6.2 14.3 13.2 3.5 10.0 6.1 7.3 6.2 3.2 10.1 2.5 29.4 8.2 135.0 9.1 21.5 33.3 7.1 4.6 1.7 8.5 4.2 17.5 9.7 26.6 8.2 15.5 37.5 38.1 12.5 3.3 1.4 7.0 16.2 32.4 42.4 25.9 14.6 22.0 30.2 1.0 16.6 2.2 3.1 0.5 0.3 8.9 1.5 16.6 5.3 15.0 6.1 8.4 4.3 5.8 32.9 10.4 35.7 13.8 39.0 13.1 86.2 8.2 10.8 11.2 7.8 11.7 KLF6 "BCD1, COPEB, CPBP, GBF, PAC1, ST12, Zf9" ENSG00000067082 "Kruppel like factor 6" Q99612 10 3775996-3785281 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 436.6" "Cell type enhanced" "Detected in all" "Squamous epithelial cells: 2075.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013529, HPA069585" Supported Supported Nucleoplasm,Nucleoli,Vesicles,Cytosol No No "Cluster 1: Neutrophils - Mixed function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Nucleoli, Vesicles, Cytosol" "CAB013529: AB_2533431, HPA069585: AB_2686157" "unprognostic (1.23e-1)" "unprognostic (1.53e-2)" "unprognostic (1.47e-3)" "unprognostic (4.53e-2)" "unprognostic (1.47e-1)" "unprognostic (7.55e-2)" "unprognostic (2.00e-1)" "unprognostic (1.08e-3)" "unprognostic (1.61e-1)" "unprognostic (2.83e-2)" "unprognostic (1.36e-2)" "unprognostic (2.35e-2)" "prognostic favorable (2.28e-4)" "unprognostic (8.07e-3)" "unprognostic (4.85e-2)" "unprognostic (6.87e-2)" "unprognostic (1.37e-2)" 211.3 46.9 19.0 122.1 18.0 436.6 129.7 19.2 22.4 95.4 21.9 92.1 55.4 98.1 17.7 165.5 77.2 181.9 49.7 18.0 19.2 64.1 141.8 117.0 65.4 29.4 20.1 47.3 118.3 31.8 12.0 98.2 25.2 32.8 99.6 18.4 73.8 33.7 84.9 197.1 106.0 208.2 22.7 64.3 73.2 14.6 23.0 56.8 193.9 41.3 45.0 136.3 92.7 25.0 55.0 14.7 27.2 9.0 155.1 154.3 17.1 91.7 46.5 95.9 64.8 38.0 71.4 15.6 20.8 100.0 74.5 32.7 17.0 84.9 79.5 76.6 10.2 2.2 17.5 35.8 66.4 10.3 51.5 51.4 158.2 68.6 129.3 34.2 99.3 10.1 17.5 117.9 123.6 4.0 19.4 15.9 10.2 29.2 26.0 12.6 28.2 55.5 94.1 53.4 12.0 11.5 22.5 64.0 142.8 73.5 32.0 8.6 130.9 128.7 17.8 76.9 43.0 22.6 78.1 28.6 34.7 13.7 40.8 318.8 85.2 234.1 129.8 74.2 115.9 81.1 147.4 131.5 67.6 70.9 44.9 69.0 391.6 72.5 104.6 152.8 120.6 148.7 19.0 18.0 19.2 22.4 18.0 19.2 29.4 20.1 25.2 22.7 23.0 25.0 511.0 1246.8 489.4 14.0 716.9 585.5 1298.4 625.8 1227.0 39.6 985.9 630.0 63.6 544.7 451.9 138.0 33.3 163.1 518.3 1507.0 21.5 808.6 58.0 1065.6 618.9 469.9 397.3 77.9 18.5 553.0 473.8 545.5 1120.3 1905.9 626.7 195.9 248.4 309.9 583.6 37.0 10.0 746.7 429.3 968.7 885.1 53.2 130.5 992.1 483.8 58.1 609.8 42.9 150.4 7.5 4.3 857.9 949.9 133.9 1172.5 600.2 1009.9 97.4 342.0 90.1 138.1 194.8 441.8 9.0 19.4 2075.6 628.2 195.9 920.5 67.1 542.0 572.5 KLHDC9 KARCA1 ENSG00000162755 "Kelch domain containing 9" Q8NEP7 1 161098361-161100346 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 29.0" "Group enriched" "Detected in many" 4 "Early spermatids: 424.7;Late spermatids: 448.2;Spermatocytes: 198.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 2.1;HDLM-2: 1.5;HEK 293: 1.8;MCF7: 1.4;T-47d: 1.4;U-266/70: 1.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043197 Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes NA "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Nucleoli, Nucleoli rim, Mitotic chromosome" "HPA043197: AB_2678359" "unprognostic (1.79e-1)" "unprognostic (2.26e-1)" "unprognostic (4.71e-2)" "unprognostic (1.04e-3)" "unprognostic (2.53e-2)" "unprognostic (1.52e-1)" "unprognostic (1.62e-1)" "unprognostic (4.87e-3)" "unprognostic (6.31e-2)" "prognostic favorable (4.20e-6)" "unprognostic (1.81e-3)" "unprognostic (1.71e-1)" "unprognostic (1.12e-1)" "unprognostic (3.53e-1)" "unprognostic (5.51e-2)" "unprognostic (6.36e-2)" "unprognostic (6.88e-2)" 0.4 3.0 1.3 0.1 1.8 0.0 0.7 1.0 2.9 1.1 2.1 1.4 0.2 1.4 0.5 0.5 2.2 0.0 0.9 1.7 2.2 4.7 1.9 0.8 0.0 1.7 1.8 1.0 2.4 1.1 4.6 0.0 1.6 1.7 0.2 0.4 1.0 0.4 0.7 0.3 0.8 0.0 1.2 0.3 1.3 29.0 2.4 0.0 2.4 0.1 0.1 1.0 0.5 0.9 0.1 1.1 0.4 1.1 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.7 0.0 0.0 0.0 1.5 1.8 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.2 0.0 0.5 0.2 0.9 1.0 0.0 0.7 0.2 0.0 1.0 0.4 0.0 0.4 0.0 0.4 1.4 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.8 1.0 2.9 1.7 2.2 1.7 1.8 1.6 1.2 2.4 0.9 2.4 0.0 6.7 8.8 1.5 0.9 11.7 11.5 0.6 13.7 15.3 16.3 9.3 14.3 11.7 29.5 2.1 2.3 0.4 7.6 56.7 10.2 424.7 57.5 2.8 3.4 5.4 0.0 8.9 5.5 3.6 3.2 3.1 10.3 1.3 1.6 3.9 9.5 0.6 3.3 6.8 10.6 16.2 0.6 0.7 448.2 8.1 0.9 7.2 2.8 0.6 35.1 1.0 6.0 1.7 3.9 8.2 8.2 2.1 6.4 2.5 47.8 77.8 20.0 13.1 2.8 4.4 198.1 15.6 2.6 0.9 0.8 1.2 1.7 8.7 8.2 KRR1 "HRB2, RIP-1" ENSG00000111615 "KRR1 small subunit processome component homolog" Q13601 12 75490863-75511636 "Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043433, HPA051690" Approved Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 52: Eosinophils - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "HPA043433: AB_10960988, HPA051690: AB_2681574" "unprognostic (2.77e-1)" "unprognostic (1.02e-1)" "unprognostic (8.21e-2)" "unprognostic (1.71e-1)" "unprognostic (2.02e-1)" "unprognostic (4.71e-2)" "unprognostic (6.01e-3)" "unprognostic (1.78e-1)" "unprognostic (1.00e-1)" "unprognostic (1.38e-1)" "unprognostic (5.85e-2)" "unprognostic (1.88e-1)" "unprognostic (2.32e-2)" "unprognostic (1.69e-1)" "unprognostic (1.61e-1)" "unprognostic (3.26e-1)" "unprognostic (1.12e-2)" 15.2 14.2 6.5 15.6 7.0 43.9 16.7 9.3 10.4 11.6 7.6 12.5 12.1 15.0 9.0 16.0 9.8 10.0 11.8 6.9 8.2 16.2 20.4 11.5 19.0 6.6 7.3 15.0 10.7 20.3 8.0 14.5 7.0 13.2 10.9 16.0 19.3 9.8 23.5 12.7 10.3 10.9 7.4 12.6 12.7 12.0 7.5 17.9 14.9 22.7 18.0 15.9 9.8 8.2 59.4 48.1 29.2 27.1 21.8 20.1 54.1 51.0 31.7 38.5 24.8 35.7 30.7 62.2 40.3 23.9 39.0 30.5 39.1 43.0 42.4 52.0 39.9 60.9 25.0 41.8 26.4 107.0 37.1 21.3 35.8 44.8 41.7 39.1 26.6 57.4 67.7 19.8 38.2 39.2 63.1 30.8 43.6 32.4 42.4 49.9 56.1 37.4 42.6 73.6 35.4 29.6 48.0 33.7 59.5 27.9 56.2 42.9 34.4 36.2 24.1 37.7 53.2 38.8 52.3 39.0 19.6 37.0 66.2 13.3 3.2 13.2 13.1 6.5 16.4 23.0 18.3 15.0 5.5 20.6 18.6 17.9 1.5 12.9 5.5 15.3 18.2 7.6 6.5 7.0 9.3 10.4 6.9 8.2 6.6 7.3 7.0 7.4 7.5 8.2 62.9 70.5 49.2 13.4 64.0 49.1 104.3 70.3 48.9 56.4 41.1 50.5 25.6 24.3 55.7 40.5 33.3 68.5 86.4 18.7 58.7 50.9 5.4 52.5 63.8 46.7 18.0 55.8 25.3 49.0 55.7 48.2 21.4 62.6 38.0 41.3 31.1 40.9 29.5 74.0 24.3 25.7 46.8 24.2 21.3 7.6 52.5 30.0 12.4 6.5 42.4 66.4 66.9 19.1 16.3 42.8 28.1 53.4 37.9 45.6 19.2 47.0 42.3 55.5 13.1 79.2 50.2 72.6 61.1 46.8 44.3 70.5 65.4 59.6 29.3 63.2 LBX1 "HPX6, LBX1H" ENSG00000138136 "Ladybird homeobox 1" P52954 10 101226195-101229794 "Predicted intracellular proteins, Transcription factors" "Differentiation, Myogenesis, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "skeletal muscle: 26.5" "Cell type enriched" "Detected in single" 5 "Skeletal myocytes: 3.2" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "cerebellum: 1.9;medulla oblongata: 3.5;pons: 2.5;spinal cord: 4.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HEK 293: 3.4;RH-30: 4.3;SCLC-21H: 9.1" "Group enriched" "Detected in some" 24 "cerebellum: 1.6;pons and medulla: 3.0" "Group enriched" "Detected in some" 18 "cerebellum: 1.2;medulla oblongata: 2.0;spinal cord: 2.0" "HPA002016, HPA002086, CAB079927" Uncertain Approved "Nucleoplasm,Nucleoli,Nuclear bodies,Cytosol" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Nucleoli, Nuclear bodies, Cytosol" "CAB079927: , HPA002016: AB_2666518, HPA002086: AB_1079242" "unprognostic (4.13e-1)" "unprognostic (3.86e-2)" "unprognostic (2.25e-2)" "unprognostic (2.29e-1)" "unprognostic (7.28e-3)" "unprognostic (3.31e-1)" "unprognostic (9.76e-2)" "unprognostic (1.45e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.5 0.4 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 26.5 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 4.3 0.0 0.0 0.0 9.1 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 3.5 0.4 2.5 4.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LIPA "CESD, LAL" ENSG00000107798 "Lipase A, lysosomal acid type" P38571 10 89213569-89414557 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 398.4" "Cell type enhanced" "Detected in many" "Hofbauer cells: 515.0;Kupffer cells: 714.8;Macrophages: 303.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 167.3;intermediate monocyte: 355.1;myeloid DC: 123.6;non-classical monocyte: 198.5" "Group enriched" "Detected in all" 6 "dendritic cells: 123.6;monocytes: 355.1" "Cell line enhanced" "Detected in many" "A-431: 354.4;AN3-CA: 367.8;ASC TERT1: 450.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034892, HPA057052" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" "Intracellular and membrane" NA NA 280000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Vesicles, Cytosol" "Nucleoplasm, Nucleoli fibrillar center" "CAB034892: AB_784329, HPA057052: AB_2683322" "unprognostic (1.27e-1)" "unprognostic (3.23e-1)" "unprognostic (1.17e-1)" "unprognostic (1.07e-1)" "unprognostic (1.61e-1)" "unprognostic (2.55e-2)" "unprognostic (7.14e-2)" "unprognostic (1.66e-1)" "unprognostic (1.19e-1)" "unprognostic (4.28e-2)" "unprognostic (1.08e-1)" "unprognostic (7.30e-3)" "unprognostic (1.39e-2)" "unprognostic (1.40e-1)" "unprognostic (4.42e-2)" "unprognostic (3.42e-2)" "unprognostic (5.71e-2)" 76.0 46.3 43.5 66.7 65.2 39.8 47.8 64.1 74.4 54.0 39.0 67.7 167.6 38.8 21.7 28.6 37.8 83.5 24.2 43.5 53.1 44.9 218.9 169.5 159.3 74.7 55.5 32.7 21.4 68.9 12.7 79.1 82.2 30.7 72.0 12.6 22.5 33.8 11.8 18.7 227.5 47.7 65.4 398.4 34.3 13.4 57.0 44.5 31.6 22.5 45.5 58.4 19.3 115.5 354.4 49.4 30.7 367.8 343.5 450.8 10.0 171.4 194.8 65.5 121.5 18.6 176.6 63.9 34.0 264.4 73.7 338.7 13.8 92.8 53.6 86.1 34.7 25.1 19.1 81.5 87.6 48.8 48.9 190.4 69.2 72.9 40.6 88.2 14.9 45.4 0.3 108.5 58.3 28.2 45.7 34.6 22.7 62.4 60.0 26.4 39.0 60.5 69.2 50.9 10.5 21.8 41.4 49.9 133.9 20.4 64.4 65.8 26.2 58.8 15.5 132.1 44.6 60.0 65.7 25.8 71.4 112.9 82.1 4.2 167.3 16.9 40.0 355.1 40.6 31.9 35.8 38.8 123.6 33.4 36.7 40.4 7.1 29.8 198.5 25.0 38.2 159.6 43.5 65.2 64.1 74.4 43.5 53.1 74.7 55.5 82.2 65.4 57.0 115.5 75.5 41.7 33.8 11.1 35.9 17.7 30.3 58.1 25.6 5.4 16.1 14.1 9.6 45.8 31.9 33.1 0.0 34.8 31.4 2.8 21.5 35.1 6.8 11.4 20.4 56.7 21.8 27.4 34.4 36.2 32.9 34.6 21.4 15.5 28.5 10.8 54.7 66.7 515.0 16.8 15.1 8.9 40.7 714.8 69.0 2.7 11.5 303.1 48.0 30.0 71.7 33.1 29.9 15.1 143.0 19.3 12.0 21.8 15.4 11.3 161.0 14.0 28.8 2.2 6.6 19.7 21.0 5.1 13.8 31.9 12.5 20.0 33.1 17.6 9.1 24.0 LMCD1 ENSG00000071282 "LIM and cysteine rich domains 1" Q9NZU5 3 8501807-8574668 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 573.4" "Cell type enhanced" "Detected in many" "Adipocytes: 287.6;Ductal cells: 122.0;Endothelial cells: 161.9;Pancreatic endocrine cells: 114.1;Smooth muscle cells: 112.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "T-reg: 20.5" "Lineage enriched" "Detected in many" 6 "T-cells: 20.5" "Cell line enhanced" "Detected in many" "HHSteC: 88.9;HSkMC: 124.9;hTEC/SVTERT24-B: 93.8;U-2197: 83.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024059 Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions,Cytosol" No No 6600 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "Plasma membrane, Cell Junctions" "HPA024059: AB_1852950" "unprognostic (2.46e-1)" "unprognostic (1.79e-1)" "unprognostic (5.13e-3)" "unprognostic (1.30e-1)" "unprognostic (2.28e-2)" "unprognostic (2.10e-1)" "unprognostic (1.56e-1)" "unprognostic (1.38e-1)" "unprognostic (2.96e-1)" "unprognostic (8.21e-3)" "unprognostic (4.29e-1)" "unprognostic (2.54e-2)" "prognostic unfavorable (8.66e-5)" "unprognostic (3.80e-2)" "unprognostic (1.33e-1)" "unprognostic (1.01e-3)" "unprognostic (3.68e-3)" 131.4 14.3 9.5 45.6 9.5 0.1 97.5 13.5 10.8 27.2 38.8 18.1 9.0 90.3 18.4 36.1 57.8 67.2 90.6 14.0 9.7 33.0 9.7 131.7 17.3 14.0 11.0 65.8 37.7 30.0 8.7 54.5 12.1 34.8 7.0 15.2 42.2 16.8 573.4 28.8 20.1 63.3 13.2 55.6 46.4 11.3 12.6 4.7 18.5 260.9 10.2 110.6 31.5 14.8 9.4 52.0 8.6 6.6 62.0 34.6 8.9 37.9 19.4 20.5 50.0 38.8 11.5 0.0 4.2 44.2 8.8 0.8 4.9 9.9 8.4 16.0 3.6 11.6 3.5 7.6 88.9 0.0 1.1 124.9 0.2 93.8 0.7 11.9 10.1 0.0 0.0 0.0 26.8 6.7 0.0 0.1 16.8 12.0 2.3 0.2 28.2 0.1 19.1 3.6 0.3 21.3 6.4 31.1 20.6 23.9 40.7 0.1 5.0 20.4 40.3 83.0 25.9 5.1 6.2 2.6 4.1 2.9 27.0 0.0 0.0 0.0 0.0 0.4 0.1 2.0 2.9 0.6 3.3 0.3 0.0 0.1 0.0 0.0 0.0 1.0 20.5 0.3 9.5 9.5 13.5 10.8 14.0 9.7 14.0 11.0 12.1 13.2 12.6 14.8 287.6 9.6 10.7 2.0 2.1 31.6 42.1 7.4 9.6 13.0 20.4 17.0 14.7 14.3 13.5 5.5 10.4 3.9 1.7 1.4 3.9 122.0 1.1 9.6 77.7 161.9 12.1 0.0 0.8 48.5 4.2 64.5 7.1 4.8 10.2 44.2 30.7 12.6 3.4 97.6 1.2 2.4 4.1 0.8 47.0 2.3 11.5 3.2 53.4 29.0 9.0 38.9 1.0 4.0 8.7 114.1 0.9 32.4 8.0 8.4 0.3 45.5 12.0 8.0 0.0 57.0 112.9 6.4 9.1 29.0 27.1 4.4 5.3 21.5 4.7 7.5 LRRC45 MGC20806 ENSG00000169683 "Leucine rich repeat containing 45" Q96CN5 17 82023305-82031151 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 27.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023372, HPA023382, HPA024768" Enhanced Supported "Nucleoplasm,Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Centrosome, Cytosol" "Nucleoplasm, Plasma membrane" "HPA023372: AB_1853317, HPA023382: AB_1853318, HPA024768: AB_10602348" "unprognostic (6.69e-2)" "unprognostic (6.10e-2)" "unprognostic (6.86e-2)" "unprognostic (1.38e-2)" "unprognostic (6.92e-2)" "unprognostic (4.41e-3)" "unprognostic (4.70e-3)" "unprognostic (1.23e-1)" "unprognostic (6.10e-2)" "unprognostic (1.78e-3)" "unprognostic (6.17e-3)" "unprognostic (7.46e-2)" "prognostic unfavorable (1.54e-4)" "unprognostic (1.22e-3)" "unprognostic (1.24e-1)" "unprognostic (4.79e-2)" "unprognostic (3.58e-1)" 5.0 6.1 2.3 3.8 2.2 7.0 5.8 7.5 5.4 6.1 2.2 8.7 5.7 5.4 0.9 10.3 9.0 1.6 5.0 2.5 1.9 7.5 18.0 6.4 3.2 3.0 2.8 4.5 10.1 2.0 5.9 2.4 3.0 8.4 1.7 0.6 9.6 2.2 2.5 8.7 8.6 1.2 2.1 9.5 10.5 4.0 2.2 3.1 8.9 0.5 1.5 6.1 6.9 2.3 18.6 20.7 6.2 12.7 2.5 3.3 24.0 12.7 5.2 7.5 6.3 18.6 12.4 13.9 11.2 2.5 7.8 21.3 6.0 7.6 1.7 8.5 38.6 8.8 43.1 25.5 2.1 10.4 21.2 3.3 3.1 4.5 1.2 3.1 11.1 13.0 6.3 6.0 2.0 31.6 23.5 34.5 6.4 15.0 27.4 19.0 12.2 7.8 4.8 16.9 19.1 18.6 5.8 29.9 11.2 3.0 24.4 12.0 6.5 13.1 16.3 20.8 21.9 11.5 3.1 2.1 7.0 8.9 13.9 2.3 1.2 1.5 1.4 0.9 1.4 0.6 1.6 1.6 0.8 0.7 0.8 1.1 0.0 1.1 0.4 1.3 1.4 1.4 2.3 2.2 7.5 5.4 2.5 1.9 3.0 2.8 3.0 2.1 2.2 2.3 3.9 6.4 2.2 4.2 4.1 4.5 5.0 2.9 1.8 5.2 8.5 8.6 2.7 14.3 7.0 3.7 0.0 12.7 7.8 18.1 5.9 7.3 1.5 19.0 3.4 3.7 4.8 10.3 2.5 4.7 27.9 4.8 13.3 5.0 4.5 13.3 7.1 12.6 8.7 5.0 2.9 12.2 4.1 6.3 3.2 4.4 7.2 4.2 8.8 0.0 4.3 5.6 7.2 1.0 1.8 5.8 9.4 6.4 8.5 2.4 10.9 10.2 24.4 4.1 0.0 2.8 5.2 2.3 11.9 6.3 2.4 3.0 7.0 4.9 18.4 3.7 LRRC7 "densin-180, KIAA1365" ENSG00000033122 "Leucine rich repeat containing 7" 1 69567922-70151945 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 20.2" "Group enriched" "Detected in many" 20 "Excitatory neurons: 1132.4;Inhibitory neurons: 996.9;Oligodendrocyte precursor cells: 1038.0;Oligodendrocytes: 408.2" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "amygdala: 6.9;basal ganglia: 17.0;cerebral cortex: 20.2;hippocampal formation: 17.7;thalamus: 11.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HaCaT: 12.6;HEL: 44.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA005625 Supported "Nucleoplasm,Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "Nucleoplasm, Centrosome" "HPA005625: AB_1853340" "unprognostic (2.81e-2)" "unprognostic (1.62e-2)" "unprognostic (1.51e-1)" "unprognostic (2.98e-3)" "unprognostic (2.47e-1)" "unprognostic (1.73e-1)" "unprognostic (1.04e-1)" "unprognostic (3.50e-2)" "unprognostic (4.84e-3)" "unprognostic (2.92e-2)" "unprognostic (1.06e-3)" "unprognostic (1.46e-1)" "unprognostic (5.64e-6)" "unprognostic (1.31e-2)" "unprognostic (1.74e-2)" "unprognostic (5.13e-3)" "unprognostic (2.08e-3)" 0.1 0.2 6.9 0.1 17.0 0.2 0.0 0.0 20.2 0.2 0.0 0.4 0.1 0.2 0.1 0.2 0.0 1.0 1.4 17.7 1.7 0.8 0.2 0.0 0.1 0.0 2.2 0.1 0.8 0.1 0.0 0.2 0.0 0.3 0.6 1.5 0.0 0.1 1.0 0.2 0.2 0.2 0.0 0.0 0.2 1.6 11.4 0.0 2.2 0.0 0.0 0.1 0.1 2.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.4 4.4 0.0 0.0 12.6 0.3 0.0 0.0 0.0 0.6 44.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 4.7 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.9 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.1 0.0 0.0 0.0 0.0 6.9 17.0 0.0 20.2 17.7 1.7 0.0 2.2 0.0 0.0 11.4 2.9 0.8 0.0 0.0 41.4 2.5 0.8 0.6 0.4 1.8 44.4 0.3 0.3 6.2 2.8 0.2 0.0 2.1 0.4 2.4 0.0 0.0 0.0 29.4 0.5 1.4 1.2 0.0 3.2 1132.4 0.0 0.5 1.8 0.0 1.4 0.0 0.6 2.9 6.5 0.3 6.7 996.9 0.0 0.0 2.8 3.6 6.3 0.6 0.5 5.4 17.8 1.7 1.0 2.1 1038.0 408.2 0.0 0.0 3.0 1.3 0.9 0.0 1.6 0.1 8.3 0.0 1.4 1.5 9.2 3.0 0.5 1.3 0.1 2.3 0.1 0.0 0.1 LRRC9 FLJ46156 ENSG00000131951 "Leucine rich repeat containing 9" Q6ZRR7 14 59919713-60063559 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 5.4;choroid plexus: 12.4;testis: 8.1" "Cell type enhanced" "Detected in some" "Early spermatids: 112.6;Excitatory neurons: 28.0;Inhibitory neurons: 18.0;Late spermatids: 75.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NTERA-2: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA040965, HPA041381, HPA077675" Uncertain Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cell Junctions" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cell Junctions" "Nucleoplasm, Nuclear bodies" "HPA040965: AB_2677225, HPA041381: AB_2677444, HPA077675: " "unprognostic (1.01e-2)" "unprognostic (2.00e-1)" "unprognostic (4.45e-2)" "unprognostic (2.12e-3)" "unprognostic (2.80e-1)" "unprognostic (2.95e-3)" "unprognostic (1.93e-1)" "unprognostic (3.11e-2)" "unprognostic (1.91e-2)" "unprognostic (4.82e-2)" "unprognostic (3.45e-3)" "unprognostic (6.06e-2)" "unprognostic (2.62e-3)" "unprognostic (8.54e-3)" "unprognostic (8.30e-2)" "unprognostic (1.67e-2)" "unprognostic (2.29e-2)" 0.3 0.1 0.9 0.0 1.6 0.1 0.0 1.0 0.6 0.0 12.4 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 1.0 1.7 0.0 0.0 0.0 0.0 5.2 5.4 0.0 0.0 0.7 0.5 0.0 3.7 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 4.3 0.0 0.0 8.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.6 1.0 0.6 1.0 1.7 5.2 5.4 3.7 4.3 1.9 5.0 0.0 0.0 0.0 6.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 112.6 1.5 0.1 0.1 0.0 0.0 28.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.7 18.0 0.0 0.0 0.0 0.0 75.8 0.9 0.1 0.0 1.9 0.0 0.8 0.0 5.5 2.0 0.0 0.0 0.7 0.0 0.7 0.4 0.0 2.9 0.2 0.0 0.0 0.0 10.3 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 LRWD1 "CENP-33, DKFZp434K1815, ORCA" ENSG00000161036 "Leucine rich repeats and WD repeat domain containing 1" Q9UFC0 7 102464956-102473168 "Predicted intracellular proteins" "DNA replication" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 11 "testis: 275.2" "Group enriched" "Detected in many" 4 "Early spermatids: 1002.6;Spermatocytes: 677.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021320 Enhanced Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Vesicles" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 78: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoli, Nucleoli rim" "Nucleoplasm, Vesicles" "HPA021320: AB_1853372" "unprognostic (1.50e-1)" "unprognostic (1.25e-1)" "unprognostic (1.31e-2)" "unprognostic (7.66e-3)" "unprognostic (1.60e-2)" "unprognostic (2.08e-3)" "unprognostic (1.72e-3)" "unprognostic (4.97e-2)" "unprognostic (3.34e-1)" "unprognostic (3.04e-2)" "prognostic favorable (8.71e-5)" "unprognostic (1.00e-1)" "prognostic unfavorable (1.25e-4)" "unprognostic (1.46e-2)" "unprognostic (4.14e-2)" "unprognostic (7.82e-2)" "unprognostic (9.20e-2)" 8.2 16.8 10.7 6.8 10.7 14.9 7.9 11.4 13.1 10.4 10.7 8.9 5.3 10.0 2.3 7.7 13.8 3.9 9.7 13.0 11.5 11.4 15.0 10.1 8.1 12.1 14.4 9.4 9.3 8.7 17.6 3.1 12.2 8.6 2.3 3.4 7.6 6.1 13.2 6.7 17.1 4.2 10.8 24.3 9.0 275.2 12.1 8.7 10.0 5.3 7.3 8.9 7.3 10.2 18.6 24.6 13.0 36.8 9.4 7.2 21.0 19.6 11.9 30.5 20.9 23.7 10.3 44.8 27.5 13.9 36.3 19.2 18.7 16.4 9.0 16.6 39.2 10.0 11.1 14.8 12.7 17.6 17.4 6.7 9.9 35.4 7.5 10.2 16.2 33.9 44.5 13.3 16.8 54.3 53.4 42.1 28.7 22.0 37.8 28.2 12.2 48.5 9.2 11.3 17.7 50.7 21.0 20.1 19.3 14.6 11.2 14.4 11.1 17.3 37.7 54.8 30.8 50.5 94.3 43.6 19.3 17.1 31.4 10.6 2.6 9.9 9.7 4.0 9.0 10.0 8.4 8.4 2.7 11.8 5.2 6.9 5.5 10.5 3.8 9.7 9.3 6.0 10.7 10.7 11.4 13.1 13.0 11.5 12.1 14.4 12.2 10.8 12.1 10.2 9.1 0.0 1.1 5.5 10.6 10.5 6.4 16.5 3.4 11.7 5.5 5.0 0.8 2.8 12.8 12.9 2.1 9.2 10.8 8.6 7.9 12.3 1002.6 54.4 7.3 6.5 7.8 13.7 4.7 10.5 12.4 7.0 10.7 13.7 0.0 14.8 5.7 7.2 8.8 5.0 5.0 9.8 18.3 3.4 4.0 172.3 19.0 5.0 5.4 2.8 7.2 7.9 10.3 4.5 2.8 12.4 11.2 15.8 20.2 3.9 8.6 15.9 65.3 11.4 0.0 5.4 13.6 677.0 38.3 4.5 9.8 6.2 9.3 22.2 7.5 3.4 MAFB KRML ENSG00000204103 "MAF bZIP transcription factor B" Q9Y5Q3 20 40685848-40689236 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 273.1" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 264.0;Hofbauer cells: 377.6;Kupffer cells: 672.8;Macrophages: 456.7;Squamous epithelial cells: 361.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 88.3;non-classical monocyte: 121.4" "Lineage enriched" "Detected in many" 15 "monocytes: 121.4" "Cell line enhanced" "Detected in some" "HSkMC: 28.6;hTCEpi: 61.2;SCLC-21H: 16.7;SiHa: 15.6;U-138 MG: 16.4;U-2197: 24.4;U-87 MG: 16.0" "Low region specificity" "Detected in many" HPA005653 Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Cytosol" Yes NA "Cluster 51: Monocytes - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "Nucleoli, Golgi apparatus, Cytosol" "HPA005653: AB_1079293" "unprognostic (1.55e-1)" "unprognostic (1.17e-2)" "unprognostic (1.16e-3)" "prognostic unfavorable (5.64e-4)" "unprognostic (9.16e-2)" "unprognostic (3.92e-2)" "unprognostic (1.10e-1)" "unprognostic (2.10e-1)" "unprognostic (2.57e-2)" "unprognostic (6.09e-2)" "unprognostic (5.45e-3)" "unprognostic (9.92e-2)" "unprognostic (3.95e-2)" "unprognostic (1.05e-1)" "unprognostic (3.21e-3)" "unprognostic (3.49e-2)" "unprognostic (2.30e-2)" 35.3 13.8 4.8 37.3 4.9 59.2 27.3 4.4 10.5 16.5 6.9 9.5 7.8 9.3 5.4 33.0 11.3 24.4 10.7 3.7 5.7 17.5 29.3 20.9 27.8 14.3 6.3 6.8 15.8 273.1 3.1 13.2 7.2 8.3 7.2 0.6 18.3 4.7 15.8 85.3 13.2 14.2 9.0 96.3 11.0 3.9 13.1 6.7 50.1 16.7 12.7 13.9 21.9 15.8 0.0 0.0 0.0 2.6 1.5 0.2 0.4 0.3 0.1 0.3 0.1 0.4 0.2 0.0 1.9 0.4 0.0 3.8 0.0 0.0 0.0 0.0 1.4 0.0 1.2 0.2 0.9 0.0 0.1 28.6 61.2 0.2 2.1 0.0 0.4 0.0 0.0 0.0 0.1 0.9 0.3 7.4 2.6 6.2 0.0 0.0 0.0 0.0 0.5 0.4 16.7 1.4 15.6 1.5 3.9 5.4 1.5 0.3 0.5 16.4 0.3 24.4 0.0 0.0 0.0 0.0 16.0 0.6 0.0 0.4 24.3 0.0 0.0 88.3 0.0 0.0 0.0 0.1 7.9 0.1 0.0 0.0 2.1 0.0 121.4 0.1 0.0 10.6 4.8 4.9 4.4 10.5 3.7 5.7 14.3 6.3 7.2 9.0 13.1 15.8 70.0 22.4 37.9 1.6 7.8 68.6 50.5 17.1 264.0 12.0 112.2 217.8 208.9 7.2 16.8 51.5 25.0 9.8 7.6 117.1 1.9 2.3 0.8 15.7 64.4 39.1 57.7 4.0 0.8 3.4 2.8 172.7 49.5 27.6 10.8 0.9 34.6 36.1 377.6 3.3 25.4 50.7 6.1 672.8 91.7 2.8 29.5 456.7 21.4 6.5 65.3 21.9 3.1 2.0 1.3 4.9 30.9 24.5 5.6 29.7 89.5 1.3 2.4 8.3 13.1 160.6 102.4 0.8 1.7 361.5 88.2 12.4 9.5 114.6 39.0 19.2 MAP1S "BPY2IP1, C19orf5, FLJ10669, MAP8, VCY2IP1" ENSG00000130479 "Microtubule associated protein 1S" Q66K74 19 17719242-17734513 "Predicted intracellular proteins" Apoptosis DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 82.9" "Group enriched" "Detected in all" 4 "Early spermatids: 98.1;Late spermatids: 293.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050934, HPA054637" Approved Supported "Nucleoplasm,Nucleoli,Cell Junctions,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 78: Testis - Spermatogenesis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "Nucleoplasm, Nucleoli, Cell Junctions" "HPA050934: AB_2681281, HPA054637: AB_2682552" "unprognostic (8.47e-2)" "unprognostic (2.39e-2)" "unprognostic (1.60e-1)" "unprognostic (2.72e-1)" "unprognostic (3.70e-1)" "unprognostic (8.23e-2)" "prognostic unfavorable (5.29e-4)" "unprognostic (2.53e-1)" "unprognostic (6.17e-2)" "unprognostic (4.39e-2)" "prognostic favorable (2.65e-4)" "unprognostic (6.33e-2)" "unprognostic (1.19e-1)" "unprognostic (1.36e-1)" "unprognostic (1.72e-1)" "unprognostic (2.09e-1)" "unprognostic (8.65e-2)" 20.5 13.9 48.2 8.7 51.9 11.2 19.1 36.8 82.9 18.9 30.1 21.5 7.7 24.8 5.4 11.9 19.2 7.9 18.8 51.4 40.5 15.4 12.4 23.5 9.0 44.7 41.1 21.6 15.6 5.4 22.0 9.7 43.3 17.4 2.4 2.8 19.7 6.5 32.4 12.2 17.7 3.6 39.2 18.3 20.1 74.7 40.6 6.1 16.1 5.4 3.9 21.6 14.6 47.7 30.1 43.2 12.4 16.9 10.4 15.4 34.0 18.3 8.8 10.9 12.3 61.3 16.0 17.3 33.8 11.4 12.8 15.3 10.5 14.5 4.6 21.8 61.1 15.1 36.3 39.2 22.1 16.8 20.9 16.7 8.3 16.7 10.5 7.9 22.6 12.5 24.2 9.5 6.0 39.0 20.8 42.0 28.7 17.1 50.8 33.3 10.2 17.5 14.8 43.4 23.0 26.5 10.7 14.8 18.9 9.0 9.9 17.8 37.3 19.7 18.2 40.7 27.2 18.1 23.3 17.4 23.7 26.7 25.1 18.5 22.6 25.9 15.7 22.2 15.1 15.7 12.3 15.6 25.9 15.5 10.1 13.9 31.4 13.0 17.9 21.2 12.2 19.0 48.2 51.9 36.8 82.9 51.4 40.5 44.7 41.1 43.3 39.2 40.6 47.7 11.1 3.2 7.5 4.2 14.7 10.3 14.0 13.1 13.1 11.1 12.3 8.6 5.5 15.7 12.1 3.7 8.4 21.7 14.0 30.9 3.9 22.2 98.1 12.9 11.5 18.5 20.4 3.8 8.4 17.2 16.9 12.3 19.4 26.9 10.2 12.0 20.7 4.8 26.1 40.4 5.5 16.6 12.2 18.7 25.1 293.2 22.4 20.7 1.8 2.8 17.4 8.1 8.2 4.5 7.1 24.2 15.8 31.6 8.8 14.9 19.0 5.9 6.2 6.3 13.1 7.7 13.0 25.9 21.4 5.4 3.3 33.8 11.3 8.1 18.3 13.7 MAP3K14 "FTDCR1B, HS, HSNIK, NIK" ENSG00000006062 "Mitogen-activated protein kinase kinase kinase 14" Q99558 17 45263119-45317029 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 33.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 40.6;U-251 MG: 43.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA027269, HPA027270" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 59: Non-specific - Translation" "Cluster 9: U-2 OS - Unknown function" "Cluster 3: Monocytes - Immune response regulation" "Vesicles, Cytosol" "Nucleoplasm, Nucleoli fibrillar center" "HPA027269: AB_2732436, HPA027270: AB_2732437" "unprognostic (1.05e-2)" "prognostic favorable (5.27e-5)" "unprognostic (2.71e-2)" "unprognostic (9.42e-2)" "unprognostic (5.31e-2)" "unprognostic (2.61e-3)" "unprognostic (2.70e-2)" "unprognostic (1.72e-1)" "unprognostic (3.40e-1)" "unprognostic (3.45e-1)" "unprognostic (1.07e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (2.78e-4)" "unprognostic (8.82e-2)" "unprognostic (3.49e-2)" "unprognostic (1.03e-2)" "unprognostic (2.28e-1)" 5.9 4.7 2.6 12.5 5.0 5.2 6.4 2.9 2.3 7.1 2.8 15.6 8.1 5.7 1.9 7.8 6.6 5.9 9.9 3.2 2.7 5.1 7.3 8.1 17.7 3.6 4.6 6.0 8.3 4.6 5.9 2.7 3.1 7.0 5.2 2.2 8.1 4.7 28.0 8.5 10.3 5.9 2.5 12.4 7.6 6.9 4.8 13.4 5.8 9.9 16.0 7.2 7.1 2.1 17.1 40.6 3.6 6.5 2.4 7.1 9.4 4.5 3.4 14.9 9.1 5.5 21.0 7.4 24.1 5.3 14.6 11.6 1.5 6.5 7.6 24.3 3.1 1.4 10.1 2.1 7.1 1.1 6.9 10.0 3.6 7.3 3.6 15.6 3.0 3.2 2.7 30.1 8.1 6.1 6.8 1.7 1.8 11.1 5.1 9.5 12.1 17.9 10.5 2.6 3.5 3.0 7.6 3.4 5.0 5.5 2.8 0.4 5.6 6.5 10.2 5.7 43.1 29.1 12.1 4.1 3.9 4.0 9.2 0.0 2.0 0.8 1.6 1.8 1.0 4.2 1.1 1.0 1.4 4.4 1.2 0.9 1.6 2.0 0.6 1.7 2.9 1.6 2.6 5.0 2.9 2.3 3.2 2.7 3.6 4.6 3.1 2.5 4.8 2.1 5.8 3.2 12.8 23.5 15.3 0.0 14.7 0.0 14.8 4.5 5.6 4.8 2.3 18.6 2.5 0.0 4.2 0.9 14.5 13.9 0.0 4.8 4.7 7.0 4.0 6.1 13.1 1.3 8.9 2.7 1.5 6.3 10.2 5.6 1.3 2.1 6.4 9.2 4.9 1.7 15.6 7.8 0.0 9.4 0.0 6.2 4.7 11.3 0.0 26.2 33.4 1.9 5.2 6.6 5.5 3.3 9.6 1.2 8.5 6.2 13.4 3.8 5.1 2.9 0.0 12.9 2.8 4.2 3.0 7.9 0.0 0.0 10.6 2.4 8.5 6.8 MAP3K6 "ASK2, MAPKKK6, MEKK6" ENSG00000142733 "Mitogen-activated protein kinase kinase kinase 6" O95382 1 27354067-27366961 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 45.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" HPA051192 Approved Approved "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Plasma membrane, Actin filaments, Cytosol" "HPA051192: AB_2681380" "unprognostic (1.19e-2)" "unprognostic (2.77e-3)" "unprognostic (2.62e-2)" "unprognostic (1.97e-2)" "prognostic unfavorable (2.13e-4)" "prognostic favorable (7.26e-4)" "prognostic unfavorable (8.76e-4)" "unprognostic (9.10e-2)" "unprognostic (2.79e-1)" "unprognostic (6.91e-2)" "unprognostic (6.56e-2)" "unprognostic (1.25e-1)" "unprognostic (4.65e-3)" "unprognostic (4.95e-2)" "unprognostic (2.79e-1)" "unprognostic (7.07e-3)" "unprognostic (1.50e-1)" 42.9 17.8 17.2 5.5 17.0 0.6 42.6 17.4 20.7 50.2 16.8 25.4 1.8 30.9 4.1 70.0 38.8 4.7 61.8 16.6 17.4 37.3 10.4 54.2 4.7 18.4 17.5 15.6 15.2 5.2 18.0 5.1 17.6 41.3 4.5 1.4 30.3 7.3 15.2 65.7 17.7 12.1 17.3 22.3 23.6 8.3 18.4 2.8 30.3 11.3 7.9 39.8 53.4 16.6 7.2 7.2 6.9 4.4 9.9 12.5 1.4 9.0 5.3 7.2 4.4 2.0 9.4 0.1 8.4 16.4 3.2 10.1 2.0 6.4 3.6 6.5 7.1 0.3 16.0 4.7 2.7 0.5 0.4 10.2 17.6 7.8 2.3 8.8 4.0 0.7 2.0 2.7 10.2 25.1 0.2 9.0 2.2 8.7 8.1 2.3 3.2 1.7 12.9 9.1 2.0 3.0 8.5 7.1 6.3 3.1 4.4 5.0 11.6 13.2 7.2 16.6 5.2 3.5 4.1 0.0 12.1 5.8 4.3 0.9 0.6 3.3 2.8 2.0 3.7 1.5 2.5 3.1 1.3 2.0 1.8 1.6 1.2 0.7 4.5 0.0 3.0 1.2 17.2 17.0 17.4 20.7 16.6 17.4 18.4 17.5 17.6 17.3 18.4 16.6 45.8 19.2 17.8 6.2 3.9 12.5 11.9 8.8 17.1 1.1 8.1 8.9 12.2 5.7 10.3 3.7 0.0 1.2 4.3 8.4 3.9 2.8 0.4 2.3 6.0 27.7 0.0 0.8 1.5 4.4 2.5 10.3 8.6 5.2 2.5 1.2 28.9 0.9 2.8 5.0 1.7 6.1 4.1 8.5 7.1 1.2 16.1 6.4 5.4 5.6 9.3 5.4 8.2 0.0 0.2 12.8 1.9 15.1 3.1 9.5 1.1 1.7 6.2 0.8 6.6 10.8 11.1 13.5 7.7 14.7 14.8 0.1 8.2 0.3 8.8 14.9 MAPK13 "p38delta, PRKM13, SAPK4" ENSG00000156711 "Mitogen-activated protein kinase 13" O15264 6 36127809-36144524 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 102.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 146.2;Late spermatids: 282.5;Proximal enterocytes: 178.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HBEC3-KT: 63.8;RPMI-8226: 40.2;RT4: 47.0" "Low region specificity" "Detected in single" "Region enriched" "Detected in all" 14 "cerebellum: 37.5" "HPA007667, CAB025854" Enhanced Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 30: Mammary glandular cells - Lactation" "Nucleoplasm, Nucleoli, Nucleoli rim, Cytosol" "CAB025854: , HPA007667: AB_1079867" "unprognostic (6.36e-2)" "unprognostic (6.88e-2)" "unprognostic (2.93e-1)" "unprognostic (6.64e-3)" "unprognostic (1.13e-2)" "unprognostic (4.80e-2)" "unprognostic (4.30e-3)" "unprognostic (5.28e-2)" "unprognostic (1.77e-1)" "unprognostic (2.14e-2)" "unprognostic (1.57e-1)" "unprognostic (7.21e-2)" "prognostic favorable (9.00e-4)" "unprognostic (3.12e-2)" "unprognostic (1.70e-1)" "unprognostic (2.21e-2)" "unprognostic (1.41e-1)" 8.7 55.9 3.1 8.8 3.0 9.4 14.2 0.5 4.4 18.6 0.0 44.6 30.9 3.4 11.5 102.4 7.6 7.5 2.5 2.9 2.2 17.3 6.7 23.8 7.9 0.6 0.0 5.4 47.7 38.9 33.3 5.6 0.2 16.7 24.4 2.7 49.5 15.5 1.2 74.1 40.1 1.9 0.1 16.1 24.1 40.0 4.2 6.9 18.9 1.0 12.4 12.2 39.3 2.7 31.4 0.3 0.7 0.5 2.4 11.2 4.3 3.3 0.4 0.3 0.8 22.3 28.4 7.0 2.0 2.5 4.6 24.4 0.3 63.8 0.7 20.0 7.9 0.2 1.2 22.8 4.0 0.4 2.2 9.2 25.9 4.3 1.0 4.5 4.1 1.2 0.6 9.4 0.9 12.7 0.4 2.6 0.4 30.9 0.4 21.0 0.5 40.2 11.6 47.0 30.5 0.7 2.5 0.5 0.2 1.3 33.0 4.1 6.3 2.4 0.4 1.0 0.7 0.8 12.7 2.3 0.1 1.3 0.2 7.6 0.4 6.5 18.3 0.1 12.3 13.9 14.5 15.4 0.1 22.0 12.8 14.4 4.6 3.8 0.1 0.2 38.0 8.6 3.1 3.0 0.5 4.4 2.9 2.2 0.6 0.0 0.2 0.1 4.2 2.7 1.5 28.9 33.0 1.0 16.4 27.3 43.5 24.9 15.4 0.7 58.8 17.7 1.7 25.8 27.3 29.5 6.2 55.3 14.9 146.2 15.6 56.9 110.3 9.1 2.8 2.1 65.5 0.0 10.0 115.9 11.8 5.0 32.1 26.2 2.5 21.1 1.1 1.7 40.3 0.0 6.7 83.2 34.6 6.8 3.3 282.5 7.2 8.8 17.8 3.7 14.2 2.1 21.6 1.5 1.2 103.6 102.2 9.8 11.4 37.1 178.4 11.5 3.7 2.4 0.0 2.2 3.4 56.6 2.9 62.6 53.3 32.3 18.5 2.5 93.0 59.9 MARCKS "80K-L, MACS, PKCSL" ENSG00000277443 "Myristoylated alanine rich protein kinase C substrate" P29966 6 113857345-113863475 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 12.7;neutrophil: 18.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 405.8;TIME: 326.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022062, HPA054820, HPA067595, HPA069443" Enhanced Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA 19000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nucleoplasm, Endoplasmic reticulum, Cytosol" "CAB022062: AB_309681, HPA054820: AB_2682613, HPA067595: AB_2732772, HPA069443: AB_2732133" "unprognostic (4.71e-1)" "unprognostic (1.91e-2)" "unprognostic (2.46e-1)" "unprognostic (5.51e-3)" "unprognostic (8.22e-3)" "unprognostic (2.38e-2)" "prognostic unfavorable (2.78e-8)" "unprognostic (7.82e-2)" "unprognostic (2.57e-1)" "unprognostic (6.92e-2)" "unprognostic (2.27e-1)" "unprognostic (3.56e-2)" "prognostic unfavorable (4.85e-4)" "unprognostic (1.36e-3)" "unprognostic (2.77e-2)" "unprognostic (8.07e-2)" "unprognostic (2.70e-2)" 42.8 16.8 65.1 58.2 64.1 104.6 50.2 73.2 78.5 31.9 21.6 75.7 38.9 31.2 13.5 45.1 27.3 35.8 18.2 56.8 89.2 24.6 26.1 35.0 45.4 81.0 87.6 39.0 42.4 7.0 20.6 63.0 73.1 37.8 68.2 22.0 28.0 18.0 15.7 32.1 43.3 30.1 106.8 57.0 62.8 10.3 85.5 44.8 16.2 12.9 45.3 86.2 34.5 102.8 39.2 22.6 405.8 22.3 134.0 86.6 2.2 123.0 171.4 84.9 140.6 40.7 54.1 0.1 25.3 228.0 67.3 118.0 67.9 35.7 109.7 0.3 40.2 0.0 22.2 53.3 89.2 10.3 0.7 90.2 68.8 81.8 77.4 231.9 243.1 0.4 4.6 107.6 122.1 0.4 1.3 0.3 52.7 43.5 29.4 0.2 40.7 4.1 26.9 73.6 56.4 163.4 78.7 39.6 89.6 95.0 2.1 11.3 326.0 78.3 0.5 129.9 212.7 288.3 22.4 11.4 60.2 55.8 153.4 0.0 3.9 0.0 0.0 12.7 0.0 4.6 0.0 0.0 1.1 1.9 0.0 0.0 18.7 0.0 7.5 0.0 0.0 0.5 65.1 64.1 73.2 78.5 56.8 89.2 81.0 87.6 73.1 106.8 85.5 102.8 211.2 9.6 15.5 44.7 139.0 504.1 540.7 232.3 275.4 157.0 213.2 176.7 16.6 57.2 115.0 38.6 29.2 7.2 5.5 629.5 37.2 144.3 55.7 111.2 444.0 271.6 336.3 2.5 33.0 229.9 11.2 372.6 135.1 130.4 2.5 526.1 236.0 8.8 371.6 84.1 21.0 369.4 126.1 286.3 605.5 35.7 120.5 381.3 273.9 60.0 447.2 315.5 2.1 194.5 9.7 208.1 223.1 67.0 105.2 380.1 89.9 6.9 145.0 37.7 39.5 89.8 222.8 22.7 16.2 326.3 638.5 29.4 22.3 62.3 352.3 620.2 MDN1 "KIAA0301, Rea1" ENSG00000112159 "Midasin AAA ATPase 1" Q9NU22 6 89642498-89819794 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 82.5;Inhibitory neurons: 79.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "K-562: 24.7;NTERA-2: 22.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029666, HPA029667, HPA029668, HPA029669" Uncertain Approved "Nucleoplasm,Nucleoli,Intermediate filaments,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nucleoli, Cytosol" "Nucleoplasm, Intermediate filaments" "HPA029666: AB_10600888, HPA029667: AB_10696207, HPA029668: AB_10669868, HPA029669: AB_10670429" "unprognostic (2.00e-1)" "unprognostic (4.46e-2)" "unprognostic (7.62e-2)" "unprognostic (2.26e-2)" "unprognostic (6.14e-3)" "unprognostic (3.46e-1)" "unprognostic (6.68e-2)" "unprognostic (1.40e-1)" "unprognostic (3.51e-1)" "unprognostic (1.75e-1)" "unprognostic (1.77e-2)" "unprognostic (9.07e-2)" "unprognostic (2.54e-3)" "unprognostic (6.28e-3)" "unprognostic (9.22e-2)" "unprognostic (2.02e-1)" "unprognostic (6.09e-2)" 4.2 4.6 3.4 1.9 3.6 4.2 4.3 4.4 3.3 4.5 1.7 4.4 1.2 5.6 2.1 4.9 5.0 1.2 4.9 3.1 3.3 4.4 9.1 3.9 2.6 3.3 3.1 7.6 5.9 3.0 4.6 1.2 3.7 3.6 1.8 3.0 3.9 1.5 8.3 7.1 5.0 1.7 2.2 4.5 4.6 6.5 3.3 2.8 6.0 3.4 2.5 4.2 4.3 5.7 4.2 4.1 4.1 3.8 6.6 6.3 4.1 2.8 2.1 3.1 3.8 9.4 1.5 12.5 3.1 2.9 3.3 3.6 10.7 3.8 5.5 4.9 7.1 13.5 5.6 6.1 2.5 17.7 3.2 3.9 3.1 8.3 7.6 1.9 5.6 5.6 24.7 2.9 3.1 5.0 2.8 6.6 22.7 3.4 3.5 5.5 7.8 3.1 2.7 5.8 7.5 3.3 3.9 2.3 2.5 5.4 1.6 7.7 7.2 2.1 3.8 2.8 6.5 3.3 3.9 5.9 2.8 9.8 3.7 3.2 0.3 0.6 0.7 0.2 0.6 1.0 1.0 0.8 0.2 1.3 1.3 1.0 0.0 1.1 0.3 3.0 0.4 0.1 3.4 3.6 4.4 3.3 3.1 3.3 3.3 3.1 3.7 2.2 3.3 5.7 13.2 28.9 19.1 55.2 19.2 29.3 8.2 6.0 30.7 24.4 14.0 11.0 39.2 11.5 16.9 14.7 25.0 5.5 25.2 6.6 0.0 6.3 7.5 20.1 21.9 15.0 7.7 58.5 82.5 8.1 7.2 13.3 19.4 25.2 6.3 26.4 6.4 48.5 6.6 18.5 79.5 7.7 6.1 6.3 9.5 4.3 7.2 8.6 12.4 33.7 6.6 8.0 9.2 35.7 74.8 6.9 3.7 8.6 26.0 18.1 4.7 2.5 12.9 18.7 0.0 33.1 12.7 37.5 50.1 26.1 30.1 3.4 19.4 17.4 10.3 8.5 MGAT4B GnT-Ivb ENSG00000161013 "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B" Q9UQ53 5 179797597-179806952 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 277.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 224.7;Proximal enterocytes: 224.5;Undifferentiated cells: 131.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "eosinophil: 5.5" "Lineage enriched" "Detected in single" 6 "granulocytes: 5.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012804, HPA052134" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles,Cytosol" "Intracellular and membrane" NA NA 19000 "Cluster 52: Eosinophils - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "Golgi apparatus, Vesicles, Cytosol" "HPA012804: , HPA052134: AB_2681741" "unprognostic (2.01e-2)" "unprognostic (8.68e-3)" "unprognostic (1.40e-1)" "unprognostic (3.83e-2)" "prognostic unfavorable (6.15e-5)" "unprognostic (3.61e-3)" "unprognostic (7.57e-3)" "unprognostic (1.22e-2)" "unprognostic (2.02e-1)" "unprognostic (5.13e-2)" "unprognostic (2.26e-2)" "unprognostic (2.27e-2)" "prognostic favorable (5.78e-4)" "unprognostic (1.52e-1)" "unprognostic (2.54e-1)" "unprognostic (1.72e-2)" "unprognostic (1.42e-1)" 48.4 105.0 17.2 19.0 16.9 24.6 39.9 16.8 19.3 37.0 18.1 147.0 134.1 36.9 13.4 75.1 37.2 23.5 103.3 18.9 14.2 124.8 277.1 61.2 15.5 16.3 15.0 41.1 63.3 22.9 37.7 17.9 15.1 42.3 65.0 4.4 57.9 11.9 43.8 53.4 168.3 14.9 14.6 52.8 96.3 30.6 18.0 10.5 60.1 14.9 16.0 38.7 42.1 16.2 84.2 85.3 40.8 93.7 117.4 65.1 71.1 48.3 98.3 44.4 34.8 91.7 226.4 14.4 122.3 108.2 193.1 61.6 57.9 110.1 32.2 121.0 33.0 43.5 75.1 78.4 85.9 53.7 13.4 70.5 76.6 44.1 53.0 165.2 89.1 16.9 28.7 38.5 73.6 92.6 8.4 47.4 24.7 123.7 35.1 21.6 31.4 40.4 132.3 158.5 67.5 39.7 73.7 75.2 139.1 33.8 51.3 56.3 109.2 106.6 48.6 61.2 80.2 32.5 39.5 35.4 125.0 68.2 78.7 0.0 0.4 5.5 0.1 0.1 0.0 0.0 0.3 0.1 0.3 0.9 0.2 0.3 0.1 0.0 0.3 0.3 0.0 0.2 17.2 16.9 16.8 19.3 18.9 14.2 16.3 15.0 15.1 14.6 18.0 16.2 35.7 12.8 9.2 9.4 7.7 12.5 17.8 12.5 5.2 15.5 29.6 30.7 24.1 37.1 11.1 27.6 4.2 8.1 22.1 224.7 3.9 66.7 0.7 27.2 17.8 24.3 22.9 5.5 11.4 54.0 11.1 15.3 78.5 50.5 5.1 39.5 26.7 89.9 17.7 30.3 10.0 72.2 14.2 20.7 11.7 2.6 15.2 24.5 10.6 9.4 16.8 25.7 6.2 4.5 6.3 89.9 114.6 17.0 7.0 49.0 224.5 22.4 7.7 11.1 13.1 16.2 24.7 1.5 6.5 21.1 11.9 14.0 12.5 24.9 131.8 64.8 MICAL2 KIAA0750 ENSG00000133816 "Microtubule associated monooxygenase, calponin and LIM domain containing 2" O94851 11 12094008-12359144 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Actin-binding, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 61.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 193.5;Inhibitory neurons: 108.8;Late spermatids: 192.7;Peritubular cells: 112.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 8.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-138 MG: 109.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030437, HPA039895, HPA040438" Approved Uncertain "Nucleoplasm,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 58: Brain - Synaptic function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus, Cytosol" "Nucleoplasm, Plasma membrane" "HPA030437: AB_10601873, HPA039895: AB_2676731, HPA040438: AB_10672896" "unprognostic (2.68e-2)" "unprognostic (1.77e-2)" "unprognostic (5.77e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (6.88e-4)" "unprognostic (2.20e-2)" "unprognostic (3.60e-2)" "unprognostic (9.32e-2)" "unprognostic (2.86e-1)" "unprognostic (1.36e-1)" "unprognostic (1.15e-2)" "unprognostic (6.47e-2)" "prognostic unfavorable (3.63e-5)" "unprognostic (4.61e-2)" "unprognostic (1.97e-1)" "unprognostic (1.21e-1)" "unprognostic (1.67e-1)" 4.7 3.8 13.9 12.2 13.6 11.6 2.5 61.6 38.1 6.9 42.6 18.8 9.8 12.3 7.2 18.6 7.4 10.0 42.2 37.8 0.0 2.3 2.9 17.5 3.3 0.0 0.0 3.9 4.1 1.0 0.2 7.3 0.0 2.9 16.3 4.0 0.8 9.6 16.8 14.0 10.8 30.8 0.0 3.3 6.7 32.5 0.0 1.9 6.1 4.1 2.5 12.4 0.3 19.9 29.1 9.7 0.4 2.7 2.3 6.8 14.2 32.1 53.7 16.2 28.3 24.3 23.3 0.2 8.4 25.3 47.7 25.0 4.0 65.1 41.6 35.9 4.8 27.5 4.1 0.9 12.8 5.3 2.7 12.7 11.1 76.0 54.6 25.3 46.9 1.6 43.5 0.8 22.9 1.2 0.3 1.6 1.2 13.6 9.8 0.3 15.2 14.2 2.1 35.5 14.3 0.8 8.6 38.6 2.9 9.9 4.5 2.3 42.6 109.6 35.0 17.4 39.6 0.9 2.6 1.5 64.3 5.2 1.4 0.1 4.2 0.5 1.3 0.7 1.5 0.1 0.8 0.4 3.4 0.2 0.0 0.4 8.9 2.2 0.4 0.9 0.7 1.5 13.9 13.6 61.6 38.1 37.8 0.0 0.0 0.0 0.0 0.0 0.0 19.9 3.2 41.7 37.1 7.2 1.2 10.1 11.8 4.5 4.0 5.7 4.2 5.3 32.2 7.2 8.5 3.7 0.0 2.6 11.2 66.5 0.0 10.2 74.4 7.8 8.9 9.2 22.6 35.6 193.5 14.3 12.6 9.0 12.2 11.4 1.3 1.4 12.8 19.6 3.4 0.0 108.8 10.6 6.1 10.1 5.6 192.7 21.1 11.1 5.4 4.7 21.6 0.5 8.2 6.6 17.5 42.5 24.0 112.8 2.1 8.9 18.3 0.9 5.5 1.6 13.1 1.9 29.4 1.2 1.3 1.7 9.5 2.3 10.8 0.7 14.5 11.9 MICAL3 KIAA0819 ENSG00000243156 "Microtubule associated monooxygenase, calponin and LIM domain containing 3" Q7RTP6 22 17787649-18024561 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Exocytosis" "Actin-binding, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 104.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 176.5;Inhibitory neurons: 164.6;Oligodendrocytes: 216.0" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 104.9" "Immune cell enriched" "Detected in some" 4 "basophil: 11.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 11.1" "Cell line enhanced" "Detected in all" "WM-115: 131.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000639, HPA003421, HPA034882" Approved Supported "Nucleoplasm,Plasma membrane,Midbody ring,Cytosol" Yes No "Cluster 38: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 17: WM-115 - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Midbody ring" "Plasma membrane, Cytosol" "HPA000639: AB_10301319, HPA003421: AB_10601134, HPA034882: AB_2674371" "unprognostic (1.65e-1)" "unprognostic (1.02e-1)" "unprognostic (3.67e-2)" "unprognostic (2.00e-2)" "unprognostic (7.68e-2)" "unprognostic (2.06e-1)" "unprognostic (4.71e-2)" "unprognostic (3.07e-3)" "unprognostic (3.41e-1)" "unprognostic (1.01e-1)" "unprognostic (4.58e-1)" "unprognostic (3.82e-1)" "unprognostic (8.86e-3)" "unprognostic (1.36e-2)" "unprognostic (1.23e-1)" "unprognostic (2.03e-2)" "unprognostic (6.64e-2)" 15.9 12.0 18.3 14.9 20.3 17.3 11.2 104.9 34.5 16.5 3.6 28.1 11.0 31.0 17.0 19.6 38.6 13.4 35.6 14.3 13.7 10.9 18.8 8.3 23.0 13.2 6.4 26.5 14.0 38.5 7.2 16.7 15.6 16.4 20.6 14.1 10.9 19.8 48.2 18.9 14.5 37.3 1.9 17.8 10.7 24.4 12.7 6.0 14.7 20.8 20.3 15.9 12.0 45.9 34.0 39.6 20.2 33.7 15.6 19.2 25.6 32.6 33.1 43.6 34.5 36.1 4.8 35.1 15.5 39.3 51.2 38.7 30.1 31.9 43.0 35.6 25.2 35.9 44.6 11.9 9.6 17.1 20.2 14.4 25.9 46.9 43.7 25.2 24.9 9.7 47.6 22.8 16.9 26.6 16.9 10.7 13.0 27.3 26.4 23.2 30.3 1.9 32.1 24.8 53.5 21.1 40.6 26.0 65.2 31.5 10.8 7.0 43.9 46.0 28.4 29.7 63.6 16.4 30.2 50.8 40.0 7.7 131.6 11.1 0.0 0.1 0.3 0.0 0.6 2.5 0.3 0.3 0.0 2.6 0.2 0.1 0.1 0.9 0.0 0.2 0.7 0.2 18.3 20.3 104.9 34.5 14.3 13.7 13.2 6.4 15.6 1.9 12.7 45.9 19.6 3.2 10.2 57.1 32.1 11.2 15.2 17.9 13.1 20.9 13.7 15.5 16.5 12.8 13.2 12.9 52.1 14.1 6.2 43.5 0.0 23.9 10.5 36.4 10.2 16.4 10.2 19.3 176.5 9.8 40.3 10.5 13.3 38.8 19.0 9.7 8.9 37.3 3.1 1.7 164.6 20.8 8.2 3.2 9.6 13.9 4.1 4.2 8.8 23.4 6.0 38.2 5.2 71.9 216.0 24.6 23.6 6.4 12.5 14.4 19.8 5.5 27.8 12.2 0.0 11.0 12.1 19.8 13.8 11.2 11.8 11.2 9.1 24.2 21.5 10.1 MNDA PYHIN3 ENSG00000163563 "Myeloid cell nuclear differentiation antigen" P41218 1 158831351-158849506 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 292.9;lymphoid tissue: 107.8" "Cell type enhanced" "Detected in many" "Hofbauer cells: 219.1;Kupffer cells: 408.5;Langerhans cells: 241.7;Macrophages: 412.0;monocytes: 1118.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "neutrophil: 6012.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 6012.8" "Group enriched" "Detected in some" 14 "NB-4: 151.8;THP-1: 282.7;U-937: 185.5" "Low region specificity" "Detected in all" "HPA034532, HPA073215" Enhanced Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Vesicles,Cytosol" NA NA 400000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "Nucleoli, Nucleoli rim, Vesicles, Cytosol" "HPA034532: AB_10669677, HPA073215: AB_2686582" "unprognostic (1.53e-2)" "unprognostic (7.84e-3)" "unprognostic (2.45e-2)" "unprognostic (1.03e-1)" "unprognostic (1.42e-1)" "unprognostic (1.41e-2)" "unprognostic (2.02e-2)" "unprognostic (7.99e-3)" "unprognostic (1.58e-2)" "unprognostic (1.46e-1)" "unprognostic (1.65e-1)" "unprognostic (9.89e-2)" "unprognostic (1.96e-2)" "unprognostic (1.07e-1)" "unprognostic (4.95e-2)" "unprognostic (2.81e-2)" "unprognostic (1.02e-1)" 24.2 14.9 2.7 82.4 2.8 292.9 6.0 2.9 4.4 6.3 3.2 6.7 3.7 4.0 1.4 7.4 5.7 26.6 4.3 2.6 3.1 3.6 11.5 47.3 15.6 5.2 4.3 2.2 4.8 3.7 1.6 20.4 4.3 3.8 7.7 12.1 5.7 3.5 3.8 5.1 7.7 20.7 5.1 107.8 4.5 5.1 4.2 14.4 3.8 19.0 14.5 23.4 1.8 5.4 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 14.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 151.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 282.7 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.2 0.0 185.5 0.0 155.4 1354.4 243.8 2.6 534.3 3.7 33.5 1.6 1.9 616.5 15.3 1.6 1.4 6012.8 2.8 270.6 9.6 1.5 1099.5 2.7 2.8 2.9 4.4 2.6 3.1 5.2 4.3 4.3 5.1 4.2 5.4 2.6 35.3 56.0 0.0 34.7 2.4 0.0 0.0 0.0 1.2 1.1 3.4 0.9 5.7 9.3 0.0 0.0 0.9 5.9 0.0 0.0 0.0 0.4 0.1 0.1 5.0 0.0 22.3 0.0 0.4 1.3 6.5 0.5 0.1 44.1 0.0 3.9 2.2 219.1 0.0 0.1 0.0 0.0 408.5 241.7 3.3 1.2 412.0 1.8 33.7 1118.9 136.1 26.8 0.5 0.1 0.0 0.0 0.0 1.1 0.0 0.0 1.7 8.0 4.8 13.1 1.5 8.2 0.9 0.3 0.4 2.3 1.0 11.7 0.0 0.0 0.1 MPHOSPH9 MPP9 ENSG00000051825 "M-phase phosphoprotein 9" Q99550 12 123152320-123244014 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 114.7;Excitatory neurons: 87.7;Inhibitory neurons: 84.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037485 Approved Uncertain "Nucleoplasm,Golgi apparatus,Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 24: NB-4 - Immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" "Nucleoplasm, Golgi apparatus, Centrosome" "HPA037485: AB_10672792" "unprognostic (2.98e-2)" "unprognostic (5.00e-1)" "unprognostic (4.36e-3)" "unprognostic (1.45e-2)" "unprognostic (1.62e-1)" "unprognostic (2.81e-1)" "unprognostic (5.81e-3)" "unprognostic (1.64e-1)" "unprognostic (1.58e-2)" "unprognostic (1.88e-1)" "unprognostic (8.34e-2)" "unprognostic (1.08e-2)" "unprognostic (6.53e-3)" "unprognostic (1.31e-2)" "unprognostic (2.75e-1)" "unprognostic (5.14e-3)" "unprognostic (1.17e-1)" 4.6 5.4 13.7 8.0 15.2 26.2 5.0 21.6 19.8 4.7 18.9 6.1 6.8 5.3 11.1 3.1 5.3 3.6 5.6 14.3 13.2 6.2 9.6 3.9 12.1 13.8 13.7 4.5 4.0 8.9 4.4 5.2 13.9 4.6 6.8 21.3 5.5 4.4 6.8 5.0 5.2 5.2 13.4 8.1 5.1 12.4 14.4 32.8 5.2 7.8 10.3 4.2 1.9 16.0 15.0 15.9 23.9 28.0 10.7 10.1 9.1 15.7 7.8 18.7 15.2 15.1 7.2 29.6 10.6 10.1 15.7 10.2 30.3 11.1 26.0 17.6 20.7 30.5 17.9 15.0 6.6 27.0 24.6 10.5 4.7 18.2 16.1 15.6 19.5 40.1 21.4 12.7 17.3 12.9 32.6 44.6 17.1 9.4 17.2 27.6 24.9 19.1 14.7 14.8 31.4 15.0 23.7 9.3 15.4 22.4 17.5 21.2 11.1 15.3 21.5 17.5 22.1 19.0 33.8 24.4 12.2 26.4 32.4 11.5 3.7 5.4 10.1 3.7 7.2 6.5 8.4 9.5 3.7 6.0 11.6 12.0 0.8 10.1 3.3 5.3 7.8 2.8 13.7 15.2 21.6 19.8 14.3 13.2 13.8 13.7 13.9 13.4 14.4 16.0 7.3 9.6 9.5 50.3 15.6 4.5 4.5 5.7 8.6 43.5 5.8 5.2 16.3 10.0 7.2 7.3 114.7 12.2 25.3 2.8 5.9 4.8 57.9 21.2 12.4 8.5 14.3 33.6 87.7 1.8 7.1 10.6 5.1 6.5 2.5 23.6 7.9 31.1 8.6 53.8 84.7 5.6 6.1 15.3 7.4 73.3 7.2 10.4 3.6 24.4 17.0 14.7 32.0 46.3 48.1 1.8 1.6 11.3 21.4 3.0 4.3 11.0 14.9 65.9 0.0 11.6 7.2 31.7 20.4 8.4 2.3 1.6 26.8 17.2 9.8 2.7 MPIG6B "C6orf25, G6b, G6b-B, NG31" ENSG00000204420 "Megakaryocyte and platelet inhibitory receptor G6b" O95866 6 31718594-31726714 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Heparin-binding, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 4.8;skin 1: 8.3" "Cell type enriched" "Detected in single" 14 "granulocytes: 10.1" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "NK-cell: 1.6" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in single" 14 "HEL: 6.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA054404, HPA073017" Approved "Nucleoplasm,Endoplasmic reticulum,Golgi apparatus,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 330000 "Cluster 15: NK-cells - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 36: HEL - Hemostasis" "Cluster 60: Granulocytes - Receptor signaling" "Golgi apparatus" "Nucleoplasm, Endoplasmic reticulum, Plasma membrane, Cytosol" "HPA054404: , HPA073017: AB_2686566" "unprognostic (1.45e-1)" "unprognostic (1.25e-1)" "unprognostic (2.93e-1)" "unprognostic (1.77e-2)" "unprognostic (1.23e-1)" "unprognostic (6.53e-2)" "unprognostic (3.53e-2)" "unprognostic (2.71e-2)" "unprognostic (1.19e-1)" "unprognostic (1.43e-2)" "unprognostic (2.70e-1)" "unprognostic (1.71e-2)" "unprognostic (1.82e-2)" "unprognostic (1.02e-1)" "unprognostic (1.34e-1)" "unprognostic (2.55e-2)" "unprognostic (1.71e-2)" 0.5 0.0 0.0 0.1 0.0 1.1 0.4 0.1 0.2 1.0 0.1 0.3 0.1 0.4 0.0 1.6 0.5 0.2 0.8 0.1 0.1 0.1 0.3 3.5 0.0 0.1 0.2 0.2 0.1 0.0 0.2 0.0 0.1 0.3 0.0 0.0 0.6 0.0 0.2 8.3 0.4 0.0 0.0 4.8 0.3 2.3 0.1 0.0 0.5 0.0 0.0 0.5 1.3 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.6 0.0 0.8 0.0 2.2 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 MRPL44 "FLJ12701, FLJ13990" ENSG00000135900 "Mitochondrial ribosomal protein L44" Q9H9J2 2 223957463-223967714 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Endonuclease, Hydrolase, Nuclease, Ribonucleoprotein, Ribosomal protein, RNA-binding" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038147, HPA038148" Approved Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Mitochondria" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 39: CACO-2 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "Nucleoplasm, Nuclear bodies, Plasma membrane" "HPA038147: AB_10671521, HPA038148: AB_2675863" "unprognostic (5.21e-2)" "unprognostic (3.48e-1)" "unprognostic (3.38e-2)" "unprognostic (3.00e-1)" "unprognostic (7.05e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (1.29e-4)" "unprognostic (2.16e-2)" "unprognostic (3.32e-1)" "unprognostic (7.65e-2)" "unprognostic (8.33e-2)" "unprognostic (6.65e-2)" "prognostic favorable (2.02e-4)" "unprognostic (2.47e-2)" "unprognostic (1.14e-1)" "unprognostic (9.93e-2)" "unprognostic (2.49e-1)" 16.2 26.9 16.2 14.9 17.4 45.4 17.6 17.1 20.3 12.9 19.0 21.8 19.3 12.7 13.2 18.0 16.3 17.5 33.8 17.1 18.8 37.4 39.3 12.5 32.5 16.2 16.1 15.2 17.4 19.7 11.6 20.0 16.8 15.3 22.9 10.0 16.1 13.2 42.6 15.7 17.9 14.4 17.5 17.8 16.2 18.2 17.8 21.4 16.2 40.6 26.5 17.1 11.5 17.9 27.3 22.6 33.1 38.3 30.6 36.1 52.4 30.0 33.6 48.0 50.4 81.0 33.4 41.1 31.9 26.0 43.9 35.3 54.5 41.5 44.1 39.0 38.7 45.0 24.0 64.4 44.9 50.0 33.1 42.5 50.9 29.1 38.7 40.4 47.8 41.4 43.7 31.6 38.9 31.9 37.8 62.9 49.4 54.8 23.6 43.8 40.6 25.5 64.3 22.8 45.0 25.7 22.0 49.0 74.8 48.6 41.4 71.2 31.5 31.8 24.7 27.3 24.5 34.5 25.9 58.7 32.2 47.4 35.6 55.7 44.5 35.3 28.5 44.8 36.5 45.9 30.4 34.4 42.2 42.3 36.5 32.3 58.1 33.8 41.2 33.9 33.7 36.3 16.2 17.4 17.1 20.3 17.1 18.8 16.2 16.1 16.8 17.5 17.8 17.9 11.7 6.4 13.1 3.9 31.3 17.8 27.4 52.6 23.9 17.3 15.6 17.4 10.4 27.1 30.0 27.6 0.0 95.3 29.5 25.0 82.2 45.3 8.1 17.1 22.3 20.7 13.1 26.5 6.5 35.1 64.8 24.9 14.3 26.6 18.4 22.0 20.7 51.5 46.6 11.8 6.9 22.0 48.8 33.3 14.5 7.9 18.0 25.4 33.8 4.7 35.3 16.5 20.6 7.5 9.7 37.2 18.1 18.0 24.8 21.7 23.6 106.1 25.6 12.7 19.7 14.2 18.8 41.1 56.3 22.8 16.6 48.7 20.9 40.9 28.3 37.6 MSRA ENSG00000175806 "Methionine sulfoxide reductase A" Q9UJ68 8 10054292-10428891 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 86.0;liver: 64.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 625.8;Inhibitory neurons: 318.6;Oligodendrocyte precursor cells: 268.9;Proximal tubular cells: 666.1" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 5 "cerebellum: 28.4" "Immune cell enhanced" "Detected in some" "eosinophil: 5.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 12.3" "Low region specificity" "Detected in all" "HPA023804, HPA075766" Approved Supported "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" No No 55000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 3: HMC-1 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Cytosol" "Plasma membrane, Actin filaments" "HPA023804: AB_1853826, HPA075766: " "unprognostic (1.55e-1)" "unprognostic (4.30e-3)" "unprognostic (1.45e-3)" "unprognostic (1.00e-2)" "unprognostic (4.21e-2)" "unprognostic (1.62e-2)" "unprognostic (1.49e-2)" "unprognostic (6.40e-2)" "unprognostic (9.69e-2)" "unprognostic (1.08e-1)" "unprognostic (1.80e-1)" "unprognostic (4.58e-2)" "unprognostic (1.07e-3)" "unprognostic (6.43e-3)" "unprognostic (4.02e-1)" "unprognostic (6.36e-3)" "unprognostic (3.07e-1)" 17.0 20.4 2.2 1.1 3.0 13.5 16.1 28.4 5.4 9.1 0.0 13.9 1.1 10.7 0.1 11.6 7.4 0.4 29.0 3.8 0.0 86.0 64.0 12.2 0.6 0.0 0.4 6.4 14.5 0.7 9.2 0.8 1.8 9.2 0.6 0.6 10.5 1.0 14.5 9.5 20.1 0.8 0.0 18.6 14.2 15.2 0.3 1.5 9.6 1.3 0.6 11.6 8.2 2.8 0.1 0.9 1.3 4.3 1.2 1.4 0.5 2.5 0.2 0.3 1.7 0.6 2.1 0.0 0.6 2.5 5.8 2.3 0.4 0.1 1.3 0.2 0.0 0.3 1.5 2.2 4.3 0.8 12.3 0.4 3.2 0.3 0.0 1.4 0.6 0.3 0.4 0.2 4.9 0.1 0.0 0.3 0.6 3.3 0.8 1.6 1.3 2.0 1.1 1.1 2.5 1.5 4.6 0.2 0.5 0.4 2.3 2.8 2.6 1.7 2.0 0.4 1.2 0.2 0.1 0.7 4.8 0.8 3.1 0.5 1.9 5.6 0.4 1.2 0.3 0.6 0.4 0.3 1.2 0.1 0.3 0.2 2.2 0.7 0.9 0.2 0.3 0.2 2.2 3.0 28.4 5.4 3.8 0.0 0.0 0.4 1.8 0.0 0.3 2.8 44.1 0.0 7.4 152.8 21.4 16.4 29.3 10.8 14.2 10.1 21.2 21.8 21.6 25.8 7.2 25.8 31.3 7.7 12.4 26.4 92.0 32.3 80.6 13.6 8.7 30.3 9.6 3.4 625.8 47.1 4.6 13.1 14.8 11.8 80.7 13.7 19.6 97.2 47.0 16.8 318.6 20.8 4.1 33.6 48.3 167.9 9.3 38.0 30.2 85.3 22.3 14.6 11.3 268.9 60.7 51.1 37.8 9.8 16.2 33.8 195.5 666.1 5.6 6.2 13.1 11.3 16.9 39.3 26.5 20.1 14.1 8.3 18.0 14.1 24.5 31.1 MXI1 "bHLHc11, MAD2, MXD2, MXI" ENSG00000119950 "MAX interactor 1, dimerization protein" P50539 10 110207605-110287365 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 264.7;Oligodendrocytes: 214.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-RPE1: 108.2;SK-MEL-30: 167.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035319, HPA035320, HPA056762" Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nucleoli, Nucleoli rim, Cytosol" "HPA035319: AB_10670588, HPA035320: , HPA056762: AB_2683229" "unprognostic (1.77e-2)" "unprognostic (2.02e-1)" "unprognostic (3.34e-1)" "unprognostic (3.03e-2)" "unprognostic (1.11e-1)" "unprognostic (1.71e-2)" "unprognostic (1.08e-2)" "unprognostic (1.03e-1)" "unprognostic (1.37e-2)" "unprognostic (1.59e-1)" "unprognostic (9.26e-3)" "prognostic unfavorable (9.17e-4)" "prognostic unfavorable (1.02e-5)" "unprognostic (3.05e-2)" "unprognostic (1.36e-2)" "unprognostic (2.29e-1)" "unprognostic (2.96e-1)" 34.0 32.7 86.8 13.2 98.0 68.0 45.1 92.9 106.1 38.8 67.0 55.9 24.4 45.6 36.2 52.3 42.4 32.8 63.2 84.9 91.1 39.2 51.1 26.4 13.8 93.9 91.8 81.4 44.7 50.6 22.1 28.5 94.7 41.0 35.0 80.2 80.1 52.1 47.3 47.6 29.6 29.8 89.3 14.8 28.0 23.3 94.9 31.2 54.5 53.2 12.3 34.6 41.2 110.8 18.2 8.3 18.0 39.6 30.7 21.4 7.4 11.1 39.2 7.1 23.1 3.2 33.5 24.6 17.6 20.0 11.3 24.3 23.5 27.8 20.0 13.5 30.9 7.3 15.7 14.5 19.5 14.3 14.4 21.7 96.0 12.4 55.2 108.2 7.1 17.5 26.9 54.9 11.3 12.3 10.1 26.1 7.7 31.0 21.2 6.1 26.0 39.9 22.8 1.6 34.3 52.4 11.1 7.3 167.1 23.3 9.9 42.2 7.7 13.5 21.0 13.6 5.6 44.6 26.1 10.0 34.3 46.1 12.7 1.8 2.7 9.7 2.7 2.3 5.1 3.9 5.1 2.8 1.6 3.6 7.7 1.9 5.6 1.4 5.0 1.7 4.8 2.0 86.8 98.0 92.9 106.1 84.9 91.1 93.9 91.8 94.7 89.3 94.9 110.8 28.9 16.0 16.8 139.1 27.9 58.0 57.9 22.8 51.2 49.9 67.2 66.8 80.2 41.5 27.6 33.1 47.9 5.4 23.0 160.7 46.9 19.3 5.1 29.1 36.4 34.1 16.9 264.7 60.8 14.8 20.1 36.0 15.8 37.3 3.8 19.1 27.8 56.6 11.1 52.2 102.5 20.1 18.3 24.1 20.5 8.8 45.1 22.6 104.9 30.9 29.9 144.2 9.2 131.7 214.9 10.4 52.5 55.7 22.5 73.4 57.0 67.1 25.3 46.0 46.0 69.6 63.0 23.8 28.2 37.4 67.3 9.7 36.9 27.4 16.6 36.9 NAA11 "ARD1B, ARD2, hARD2" ENSG00000156269 "N-alpha-acetyltransferase 11, NatA catalytic subunit" Q9BSU3 4 79225694-79326061 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 2.6;placenta: 4.2;testis: 6.2" "Group enriched" "Detected in some" 12 "Cytotrophoblasts: 19.4;Early spermatids: 30.6;Extravillous trophoblasts: 16.4;Late spermatids: 23.9;Spermatocytes: 25.1;Spermatogonia: 15.9;Syncytiotrophoblasts: 13.3" "Cancer enriched" "Detected in some" 4 "testis cancer: 2.1" "Region enriched" "Detected in single" 5 "cerebellum: 2.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "GAMG: 19.3;K-562: 12.3;U-266/70: 32.9;U-266/84: 11.3" "Not detected" "Not detected" HPA035922 Approved Supported "Nucleoplasm,Golgi apparatus,Centrosome,Cytosol" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Golgi apparatus, Centrosome, Cytosol" "HPA035922: AB_10673490" "unprognostic (7.37e-2)" "unprognostic (7.58e-2)" "unprognostic (1.36e-1)" "unprognostic (1.20e-1)" "unprognostic (4.67e-1)" 0.0 0.0 0.2 0.0 0.2 0.0 0.0 2.6 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.5 0.4 0.1 0.0 0.0 0.0 4.2 0.3 0.1 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 6.2 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.0 19.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 12.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 3.3 0.0 0.3 0.3 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.2 0.0 32.9 11.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 2.6 0.1 0.1 0.2 0.5 0.4 0.3 0.3 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 19.4 0.0 0.0 0.0 0.0 30.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 16.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 23.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.1 15.9 0.0 0.0 13.3 0.0 0.0 0.0 0.0 NBEA "BCL8B, FLJ10197, KIAA1544, LYST2" ENSG00000172915 Neurobeachin Q8NFP9 13 34942270-35673022 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 23.5;retina: 65.7" "Group enriched" "Detected in many" 4 "Excitatory neurons: 1016.1;Inhibitory neurons: 953.0;Oligodendrocyte precursor cells: 466.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 33.1;SH-SY5Y: 80.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039730, HPA040385" Enhanced Supported "Nucleoplasm,Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "Nucleoplasm, Nucleoli, Cytosol" "HPA039730: AB_10794202, HPA040385: AB_10795523" "unprognostic (1.80e-2)" "unprognostic (2.90e-1)" "unprognostic (4.99e-2)" "unprognostic (3.89e-4)" "unprognostic (3.59e-1)" "unprognostic (2.04e-1)" "unprognostic (8.75e-2)" "unprognostic (6.95e-3)" "unprognostic (5.01e-1)" "unprognostic (7.43e-2)" "unprognostic (1.03e-3)" "unprognostic (2.45e-1)" "prognostic favorable (7.86e-8)" "unprognostic (2.28e-2)" "unprognostic (9.35e-2)" "unprognostic (1.17e-1)" "unprognostic (6.46e-2)" 2.4 7.2 7.7 1.5 10.7 0.3 4.9 19.0 23.5 3.5 2.8 5.8 1.4 6.1 2.2 3.3 5.5 3.4 6.9 17.4 2.8 4.1 0.6 2.0 1.6 4.1 0.1 6.2 3.1 7.1 8.3 0.6 4.8 6.6 2.5 65.7 4.7 8.4 5.6 1.5 2.5 6.5 0.4 3.2 2.7 3.5 0.0 5.6 6.3 5.7 1.2 3.6 2.8 4.5 0.0 4.5 10.9 6.1 0.7 0.1 0.3 7.0 10.8 7.9 6.6 0.1 1.0 3.0 0.0 12.9 4.7 0.3 3.7 1.5 16.3 1.4 3.6 0.0 3.4 1.2 0.5 1.9 4.7 2.1 1.2 0.1 0.7 33.1 1.8 1.2 0.1 17.6 1.1 1.9 1.1 0.0 4.6 6.2 2.0 1.1 4.7 0.9 9.3 2.1 6.2 80.1 5.4 0.1 3.6 8.1 2.0 0.4 0.1 2.0 1.2 0.0 1.6 1.9 0.5 1.3 5.4 0.6 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 7.7 10.7 19.0 23.5 17.4 2.8 4.1 0.1 4.8 0.4 0.0 4.5 19.7 28.9 9.2 132.9 5.2 1.0 5.3 2.7 1.2 124.8 5.0 6.5 51.8 11.5 14.1 9.2 146.0 0.1 4.4 0.3 1.9 9.2 19.3 5.6 18.4 10.1 22.9 0.8 1016.1 1.8 0.1 12.3 2.0 0.6 25.2 20.7 11.0 0.3 0.9 47.1 953.0 2.1 6.1 3.5 3.9 13.6 17.7 3.5 7.2 150.9 1.2 69.1 0.0 466.9 163.7 2.3 0.1 19.2 5.8 8.5 0.2 7.6 56.5 87.0 6.6 22.2 13.1 8.5 8.0 0.3 0.9 0.0 1.2 11.9 1.1 13.5 NCL "C23, Nsr1" ENSG00000115053 Nucleolin P19338 2 231453531-231483641 "Plasma proteins, Predicted intracellular proteins" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004210, HPA023981, HPA071110" Supported Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No 1400000 "Cluster 27: Non-specific - Gene expression" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nucleoli, Nucleoli rim" "Mitotic chromosome" "CAB004210: AB_670270, HPA023981: AB_1854688, HPA071110: " "unprognostic (1.91e-1)" "unprognostic (2.53e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (2.28e-4)" "unprognostic (1.63e-2)" "unprognostic (2.72e-3)" "prognostic unfavorable (1.41e-6)" "unprognostic (3.74e-2)" "unprognostic (4.31e-3)" "unprognostic (9.78e-2)" "unprognostic (6.70e-3)" "unprognostic (6.07e-2)" "unprognostic (1.66e-2)" "unprognostic (2.57e-2)" "unprognostic (9.70e-2)" "unprognostic (2.84e-2)" "unprognostic (1.42e-2)" 212.0 192.8 128.8 226.0 146.3 301.4 228.7 129.1 139.6 180.0 114.1 183.6 160.7 205.2 150.2 228.8 173.2 132.2 164.3 115.9 152.3 166.2 218.5 147.4 289.7 148.8 141.5 258.2 209.0 258.9 115.9 203.4 140.4 155.4 219.2 147.1 157.0 160.9 350.9 197.1 157.4 201.0 137.9 176.3 164.7 126.2 142.1 347.0 198.4 228.2 329.0 271.1 169.1 143.9 718.3 691.8 715.7 640.1 485.7 592.0 823.0 790.4 497.2 690.8 628.2 1227.4 521.4 1083.7 608.6 651.0 892.6 719.5 1614.4 1059.9 1284.7 554.6 644.0 1587.3 605.9 1749.5 544.0 1930.4 632.7 513.5 613.2 872.3 1019.6 394.9 834.2 770.5 1745.4 378.6 760.5 1176.4 1443.2 1086.7 1202.0 728.7 435.9 1290.8 1452.0 918.4 583.8 959.9 749.0 502.0 555.8 704.5 706.9 625.7 476.8 985.3 686.3 611.4 626.7 714.5 1063.7 624.3 554.5 1885.9 467.2 1173.1 685.2 27.3 95.6 62.5 136.5 100.3 152.8 113.5 118.4 121.9 130.6 111.9 130.3 114.2 16.8 177.8 121.7 102.0 102.3 151.0 128.8 146.3 129.1 139.6 115.9 152.3 148.8 141.5 140.4 137.9 142.1 143.9 286.2 291.7 411.7 8.1 468.9 459.9 633.8 241.0 644.9 145.0 315.2 303.8 320.9 147.3 401.6 195.0 47.9 386.9 596.2 215.0 230.9 294.4 20.6 348.7 669.8 291.1 200.0 419.2 9.3 254.4 444.6 370.9 292.0 421.8 451.7 262.7 130.6 242.0 239.5 80.8 10.4 319.6 156.6 133.7 231.1 32.2 217.2 281.8 165.4 10.3 268.9 199.6 346.1 14.1 14.9 268.0 153.9 159.9 543.5 651.1 120.1 277.6 250.3 141.0 151.2 548.9 442.0 433.3 532.4 707.9 441.4 379.0 454.0 442.6 380.6 449.1 NELFCD "HSPC130, NELF-C, NELF-D, TH1, TH1L" ENSG00000101158 "Negative elongation factor complex member C/D" Q8IXH7 20 58981208-58995133 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050641, HPA066262, HPA074936" Enhanced Supported "Nucleoplasm,Nuclear bodies,Vesicles,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 39: CACO-2 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Nuclear bodies" "Vesicles, Cytosol" "HPA050641: AB_2681198, HPA066262: AB_2685644, HPA074936: " "unprognostic (1.70e-2)" "unprognostic (1.27e-1)" "unprognostic (2.60e-1)" "prognostic unfavorable (4.98e-5)" "unprognostic (6.20e-2)" "unprognostic (2.42e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (1.47e-1)" "unprognostic (3.58e-1)" "unprognostic (1.02e-1)" "unprognostic (6.07e-3)" "prognostic unfavorable (3.37e-4)" "unprognostic (4.62e-2)" "unprognostic (2.96e-1)" "unprognostic (9.88e-2)" "unprognostic (1.34e-1)" "unprognostic (2.59e-1)" 18.9 29.5 20.5 17.7 22.8 23.8 24.5 21.7 23.4 20.7 21.2 18.2 19.3 18.2 16.3 32.9 24.4 16.2 16.9 19.6 21.0 31.7 31.2 14.7 26.4 21.2 20.9 25.2 21.2 30.7 31.8 25.6 21.8 20.4 17.9 31.9 30.0 17.1 29.4 25.9 19.6 14.1 20.8 20.7 19.3 27.9 21.5 31.5 28.5 20.5 27.9 22.6 22.7 24.3 54.7 57.6 68.5 71.9 22.5 38.9 49.6 42.4 38.8 117.1 66.8 189.6 70.7 68.3 64.0 39.8 60.8 89.1 90.1 98.0 94.8 22.4 64.1 90.5 72.4 150.5 26.7 64.2 60.1 40.9 34.3 44.2 32.8 32.8 68.3 54.0 118.1 51.8 53.3 198.2 135.6 95.4 40.3 151.5 122.9 78.4 56.6 121.1 49.0 76.5 75.9 112.6 126.0 148.3 85.9 38.2 157.5 75.0 30.2 91.6 88.8 36.3 67.7 44.4 80.0 71.1 53.7 57.3 80.6 20.0 44.6 22.9 42.0 51.5 50.0 48.6 39.7 51.2 64.9 44.5 37.7 40.1 5.6 47.1 68.8 33.0 39.7 49.0 20.5 22.8 21.7 23.4 19.6 21.0 21.2 20.9 21.8 20.8 21.5 24.3 23.0 9.6 27.6 18.3 50.5 30.2 62.6 43.8 40.9 67.3 32.7 34.2 10.9 47.1 24.3 22.0 41.7 133.1 35.5 14.5 50.9 57.0 18.8 26.2 33.3 26.7 23.4 60.0 23.0 31.4 69.2 26.2 26.5 27.4 16.5 50.9 23.2 24.1 36.9 55.5 22.8 21.9 26.4 15.3 24.0 32.1 37.0 24.0 26.6 10.3 48.1 52.9 49.4 21.1 23.6 34.9 14.4 26.4 37.4 37.8 27.8 49.9 15.0 61.5 39.5 31.6 34.2 63.1 94.9 40.5 31.4 103.0 48.5 43.9 36.2 52.8 NEXMIF "KIAA2022, KIDLIA, MRX98, XPN" ENSG00000050030 "Neurite extension and migration factor" Q5QGS0 X 74732856-74925472 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Developmental protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.7" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 3.6;Breast glandular cells: 1.4;Club cells: 2.5;Hofbauer cells: 1.3;Respiratory ciliated cells: 2.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "HAP1: 3.7;Karpas-707: 5.9;SiHa: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000407 Uncertain Supported "Nucleoplasm,Midbody,Mitotic spindle,Cytosol" Yes NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Midbody, Mitotic spindle, Cytosol" "HPA000407: AB_2665984" "unprognostic (1.04e-3)" "unprognostic (6.07e-5)" "unprognostic (1.81e-2)" "unprognostic (2.07e-5)" "unprognostic (2.15e-1)" "unprognostic (2.18e-2)" "unprognostic (3.37e-1)" "unprognostic (1.74e-3)" "unprognostic (3.71e-1)" "unprognostic (1.79e-2)" "unprognostic (1.64e-3)" "unprognostic (8.25e-2)" "unprognostic (7.58e-3)" "unprognostic (1.37e-2)" "unprognostic (3.80e-2)" "unprognostic (2.79e-4)" "unprognostic (6.94e-4)" 0.1 0.9 3.0 0.1 3.1 0.0 0.3 1.0 2.5 0.4 0.0 0.8 0.1 0.5 0.2 0.3 0.3 0.1 0.0 2.6 6.7 0.7 0.0 0.1 0.1 0.3 0.7 0.4 1.5 1.8 1.7 0.1 0.5 0.9 0.3 1.0 0.4 0.6 0.0 0.3 0.4 0.7 0.2 0.1 0.6 0.2 4.8 0.0 0.4 0.1 0.1 0.2 0.2 0.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 5.9 0.0 0.1 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 5.3 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 3.1 1.0 2.5 2.6 6.7 0.3 0.7 0.5 0.2 4.8 0.7 0.3 0.0 3.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.4 0.6 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.9 0.1 0.4 0.0 0.5 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.2 2.9 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 NIN ENSG00000100503 Ninein Q8N4C6 14 50719763-50831162 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 43.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 240.5;Muller glia cells: 150.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "basophil: 31.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005939, HPA070691" Approved Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Centrosome" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli, Nucleoli rim, Centrosome" Nucleoplasm "HPA005939: AB_2667474, HPA070691: AB_2686296" "unprognostic (1.98e-1)" "unprognostic (1.06e-1)" "unprognostic (3.54e-2)" "unprognostic (3.96e-1)" "unprognostic (1.52e-1)" "unprognostic (1.43e-2)" "unprognostic (3.41e-2)" "unprognostic (3.31e-1)" "unprognostic (5.81e-3)" "unprognostic (1.78e-2)" "unprognostic (2.07e-1)" "unprognostic (4.06e-1)" "unprognostic (2.46e-2)" "unprognostic (2.67e-1)" "unprognostic (1.28e-1)" "unprognostic (2.58e-2)" "unprognostic (7.66e-3)" 11.2 4.4 10.1 19.9 10.8 43.2 8.9 9.5 15.0 7.2 0.0 8.3 4.8 7.7 2.8 12.9 10.5 8.9 18.2 10.4 0.9 6.7 5.7 9.5 25.9 0.0 1.3 9.7 7.2 9.0 8.9 16.8 0.0 6.9 8.6 19.1 5.4 5.4 6.0 12.9 7.1 10.3 0.0 16.2 9.3 5.2 3.0 19.9 7.7 7.4 23.7 13.6 5.7 7.5 29.1 21.6 42.4 36.8 16.7 26.8 20.4 26.5 22.1 21.4 18.0 14.7 14.6 48.5 17.7 35.5 19.9 32.5 34.2 16.3 45.3 34.7 10.4 25.1 13.2 12.3 9.8 41.6 57.5 18.4 11.4 37.2 14.9 13.3 34.6 25.9 6.6 26.3 31.8 36.8 22.6 14.0 6.4 10.1 23.6 37.1 81.6 5.7 20.1 42.9 18.6 22.2 34.0 9.6 25.1 10.2 21.2 39.3 50.9 55.2 74.3 20.5 29.0 18.6 12.1 34.3 14.4 32.8 30.4 31.9 2.9 24.0 3.9 2.5 3.3 8.9 2.4 6.2 2.0 6.2 5.1 4.7 9.6 2.9 2.1 7.7 2.5 1.4 10.1 10.8 9.5 15.0 10.4 0.9 0.0 1.3 0.0 0.0 3.0 7.5 34.0 6.4 7.7 100.2 85.6 18.4 9.1 10.2 18.8 13.3 13.3 10.9 68.0 14.3 27.1 11.0 62.6 12.4 102.7 8.7 3.9 7.3 22.2 17.3 28.5 26.7 12.6 29.0 240.5 4.2 11.3 32.9 7.7 14.9 31.6 3.9 21.8 4.4 22.7 6.7 110.4 5.7 20.3 46.8 42.2 10.4 8.4 61.3 23.2 63.7 63.2 150.2 57.7 105.6 75.1 5.2 6.2 9.4 48.1 16.5 3.2 7.3 29.4 21.0 32.9 44.9 24.1 0.2 4.3 20.1 21.0 9.7 56.2 21.8 6.9 15.5 NINJ2 ENSG00000171840 "Ninjurin 2" Q9NZG7 12 564296-663779 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.1" "Cell type enhanced" "Detected in many" "Adipocytes: 29.8;Alveolar cells type 2: 39.9;Erythroid cells: 35.4;Hofbauer cells: 30.7;Kupffer cells: 38.3;Oligodendrocytes: 109.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 153.5;MOLT-4: 263.8;THP-1: 54.4;U-698: 49.3" "Low region specificity" "Detected in all" "HPA058980, HPA067226" Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane,Centriolar satellite,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 70: Brain - Nervous system development" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "Nucleoplasm, Plasma membrane, Centriolar satellite, Cytosol" "HPA058980: AB_2683869, HPA067226: " "unprognostic (1.16e-1)" "unprognostic (2.19e-1)" "unprognostic (9.51e-2)" "unprognostic (6.25e-3)" "unprognostic (1.37e-1)" "prognostic favorable (5.31e-4)" "unprognostic (5.72e-3)" "unprognostic (1.90e-3)" "unprognostic (4.60e-2)" "unprognostic (4.98e-3)" "unprognostic (5.88e-2)" "unprognostic (5.12e-2)" "unprognostic (2.68e-2)" "unprognostic (9.05e-2)" "unprognostic (1.03e-2)" "unprognostic (3.51e-3)" "unprognostic (1.23e-1)" 20.6 1.8 21.0 11.3 30.8 38.3 16.5 25.9 29.6 7.8 14.5 5.7 5.2 4.3 2.5 9.6 4.1 5.3 12.2 21.8 23.7 2.1 18.7 36.8 14.8 30.5 26.7 1.0 1.9 0.8 1.5 4.4 28.5 4.3 4.9 0.5 7.4 2.9 38.2 11.3 6.4 5.5 23.9 13.3 4.2 5.5 26.0 8.8 4.0 12.8 11.2 8.5 6.5 45.1 1.7 0.4 0.1 1.8 0.3 0.6 2.9 0.2 0.0 0.0 0.1 3.1 11.8 0.0 0.6 6.1 1.7 0.2 0.2 0.0 0.0 8.6 0.1 153.5 34.2 1.9 0.0 4.3 6.1 2.2 0.2 0.0 0.0 0.0 3.1 3.2 9.0 25.5 0.1 0.1 263.8 8.5 2.6 0.1 0.0 6.8 0.2 0.8 2.7 0.0 0.1 0.0 28.3 0.2 0.0 0.3 0.3 54.4 0.7 0.0 1.5 9.8 0.2 0.1 4.2 49.3 0.4 28.5 0.1 6.7 58.1 48.3 32.8 47.2 9.8 18.8 36.2 34.9 49.9 17.7 7.7 16.7 112.9 21.4 39.4 26.2 157.3 33.4 21.0 30.8 25.9 29.6 21.8 23.7 30.5 26.7 28.5 23.9 26.0 45.1 29.8 22.4 39.9 0.3 5.3 5.7 0.3 2.5 6.2 0.0 1.3 1.3 1.5 1.5 8.7 0.0 0.0 2.6 8.9 2.1 1.9 0.2 3.1 5.5 1.6 9.4 4.2 35.4 1.7 0.0 3.9 13.5 1.1 1.2 2.5 0.4 4.2 11.2 30.7 0.0 1.0 3.5 0.0 38.3 7.8 3.1 8.1 18.0 7.2 11.2 12.4 0.2 7.2 3.5 109.7 0.8 2.6 4.1 8.1 0.1 2.1 0.2 5.0 0.1 0.0 1.3 1.6 3.3 3.1 7.6 5.5 0.8 12.5 0.1 3.1 0.2 NISCH "I-1, IRAS, KIAA0975" ENSG00000010322 Nischarin Q9Y2I1 3 52455118-52493068 "FDA approved drug targets, Predicted intracellular proteins" Apoptosis Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Enteroendocrine cells: 169.3;Peritubular cells: 246.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023189 Approved Approved "Nucleoplasm,Vesicles,Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 34: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Nucleoplasm, Cytosol" "Vesicles, Microtubules, Cytokinetic bridge" "HPA023189: AB_1854495" "unprognostic (6.66e-2)" "unprognostic (1.58e-1)" "unprognostic (1.59e-3)" "unprognostic (4.11e-3)" "unprognostic (1.64e-1)" "unprognostic (8.08e-3)" "unprognostic (1.60e-2)" "unprognostic (6.56e-3)" "unprognostic (4.96e-2)" "unprognostic (8.33e-3)" "prognostic favorable (1.91e-4)" "unprognostic (1.40e-2)" "unprognostic (5.10e-2)" "unprognostic (1.19e-1)" "unprognostic (2.94e-2)" "unprognostic (1.47e-1)" "unprognostic (7.05e-3)" 55.2 69.8 46.5 28.7 55.5 38.7 60.5 78.2 56.6 105.8 22.2 68.5 24.3 76.2 34.0 51.3 72.0 29.9 48.5 56.3 38.7 54.6 45.6 56.2 32.5 20.9 32.6 93.0 54.1 32.5 181.8 39.1 32.9 107.5 20.6 19.0 53.6 51.6 36.3 80.7 55.3 33.0 9.1 54.1 52.7 84.5 35.2 30.1 60.8 16.3 23.3 78.1 71.6 35.2 15.6 16.0 48.8 40.1 35.7 39.2 40.0 32.8 21.5 25.7 26.0 24.2 22.8 21.7 9.0 45.6 21.0 20.4 26.1 35.7 15.1 22.3 28.2 39.2 65.2 23.9 32.4 23.2 33.6 61.9 28.2 27.7 23.5 54.0 42.0 42.4 21.1 23.4 24.3 22.2 41.8 51.2 30.1 19.8 27.1 24.5 13.4 25.4 29.2 30.6 20.6 35.9 35.6 9.3 23.1 42.3 28.9 38.5 46.3 36.0 34.1 36.9 24.1 38.7 23.8 27.3 24.7 37.3 22.4 5.2 4.5 3.5 3.0 4.0 3.1 2.5 2.6 4.0 2.3 2.8 3.1 3.3 1.5 3.2 0.6 3.4 3.0 3.6 46.5 55.5 78.2 56.6 56.3 38.7 20.9 32.6 32.9 9.1 35.2 35.2 26.1 25.6 32.3 34.0 14.9 27.5 14.6 23.3 40.5 40.9 29.2 37.1 20.4 8.6 19.1 14.7 8.4 32.4 24.2 20.5 9.8 12.1 10.3 14.5 26.7 22.1 169.3 4.6 64.9 9.4 14.0 23.4 23.4 18.9 25.3 40.2 46.1 15.3 30.5 28.6 44.0 19.1 22.4 50.5 14.5 25.9 88.3 24.3 19.6 15.0 13.0 12.1 17.5 21.1 26.1 10.0 14.2 246.0 12.4 12.6 16.5 15.6 15.2 22.4 26.3 17.2 24.8 31.2 18.0 16.7 22.3 24.2 18.4 47.6 15.7 11.7 NOL12 "MGC3731, Nop25, RRP17" ENSG00000273899 "Nucleolar protein 12" Q9UGY1 22 37681673-37693476 "Predicted intracellular proteins" "RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 105.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA003547 Uncertain Approved "Nucleoplasm,Nucleoli,Mitotic chromosome,Vesicles" Yes No "Cluster 34: Basophils - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoli, Mitotic chromosome" "Nucleoplasm, Vesicles" "HPA003547: AB_10602012" "unprognostic (3.37e-2)" "prognostic favorable (6.80e-5)" "unprognostic (2.65e-1)" "unprognostic (9.62e-2)" "unprognostic (2.13e-1)" "unprognostic (7.89e-2)" "unprognostic (3.23e-3)" "prognostic favorable (9.41e-4)" "unprognostic (9.96e-2)" "unprognostic (4.62e-2)" "unprognostic (2.18e-3)" "unprognostic (4.60e-2)" "prognostic unfavorable (2.56e-6)" "unprognostic (1.34e-2)" "unprognostic (8.40e-2)" "unprognostic (4.65e-2)" "prognostic favorable (3.24e-4)" 17.1 29.2 11.3 15.1 12.7 28.7 17.5 12.1 18.0 20.5 9.6 21.3 14.9 15.5 7.9 35.1 16.2 9.0 18.6 11.8 12.3 22.0 16.2 14.3 20.9 12.3 11.8 18.5 17.5 11.5 16.5 8.1 12.1 19.8 9.5 4.9 20.5 4.4 12.6 22.7 19.5 6.6 11.2 26.5 18.8 10.4 11.8 16.1 23.1 8.2 12.6 17.1 23.3 12.9 38.3 33.5 24.4 29.5 8.1 7.8 32.2 17.1 7.7 7.4 8.4 20.0 15.7 30.2 9.8 6.2 8.1 41.4 11.6 50.0 2.2 34.4 51.9 26.3 28.9 43.6 21.3 59.3 38.2 9.6 12.4 31.2 11.7 10.0 15.3 16.7 19.8 26.9 6.8 32.3 36.4 48.0 29.5 16.6 46.7 48.5 16.7 24.7 18.2 10.1 19.2 40.3 22.1 19.5 30.8 2.7 26.9 31.0 22.9 34.2 32.5 24.8 34.5 24.0 29.9 41.0 33.3 46.2 40.0 57.3 24.4 26.9 15.1 28.4 11.7 14.1 14.8 13.6 17.6 15.8 14.8 12.6 53.1 16.7 33.8 13.6 22.3 11.9 11.3 12.7 12.1 18.0 11.8 12.3 12.3 11.8 12.1 11.2 11.8 12.9 10.9 3.2 15.3 4.9 15.3 39.0 13.7 33.0 25.0 11.0 10.2 7.7 3.5 7.2 20.3 14.7 6.2 19.4 11.0 35.6 3.9 25.7 105.7 5.4 5.0 12.9 12.6 8.8 11.4 29.1 16.2 10.2 15.8 4.7 15.2 9.7 10.8 6.2 13.9 28.6 10.9 24.8 20.3 10.7 21.8 48.3 9.9 12.7 21.4 2.8 17.7 13.8 18.6 5.5 8.2 22.4 39.9 11.3 14.0 8.6 27.4 7.8 15.9 8.3 13.1 10.0 10.6 14.5 25.9 45.4 39.8 19.8 14.3 9.7 24.1 14.5 NPHP4 "KIAA0673, POC10, SLSN4" ENSG00000131697 "Nephrocystin 4" O75161 1 5862811-5992473 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ciliopathy, Disease variant, Leber congenital amaurosis, Nephronophthisis, Senior-Loken syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 24.2;Cone photoreceptor cells: 33.3;Excitatory neurons: 47.1;Inhibitory neurons: 30.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebral cortex: 2.7;hippocampal formation: 3.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063852, HPA065526" Approved Approved "Nucleoplasm,Nuclear bodies,Vesicles,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Cytosol" "Nuclear bodies, Vesicles" "HPA063852: , HPA065526: AB_2685505" "unprognostic (1.82e-1)" "unprognostic (1.57e-2)" "unprognostic (1.76e-1)" "unprognostic (7.30e-2)" "unprognostic (5.83e-2)" "unprognostic (2.53e-2)" "unprognostic (1.08e-2)" "unprognostic (1.95e-1)" "unprognostic (2.52e-1)" "unprognostic (1.23e-2)" "unprognostic (7.49e-3)" "unprognostic (9.00e-2)" "unprognostic (1.75e-2)" "unprognostic (2.96e-2)" "unprognostic (1.34e-1)" "unprognostic (2.54e-1)" "unprognostic (1.37e-1)" 2.7 2.2 1.0 2.3 0.8 3.7 2.7 0.0 2.7 2.9 2.5 2.2 2.1 2.8 2.3 2.0 7.9 2.1 1.9 3.1 0.0 2.2 1.3 3.0 2.3 0.0 0.0 2.9 2.4 2.7 7.8 1.6 0.0 2.2 1.2 2.4 2.2 2.3 2.2 4.9 2.1 2.2 0.0 2.2 2.0 5.3 0.0 2.5 6.7 1.9 1.1 2.1 2.5 0.0 7.8 4.8 5.4 4.3 4.7 6.8 4.1 3.9 3.9 5.3 4.2 4.1 6.5 4.0 9.6 4.6 3.6 7.4 2.7 6.6 2.7 5.1 7.3 3.4 8.1 4.1 3.7 6.5 5.1 5.6 3.2 6.3 3.9 3.4 3.8 9.4 6.2 4.1 2.4 5.9 8.3 7.1 1.0 4.0 5.5 7.1 3.4 6.5 2.6 1.0 17.0 5.5 6.1 4.5 6.5 2.3 6.0 7.2 3.7 7.6 3.2 13.0 4.8 5.0 7.0 4.2 3.4 8.3 2.0 0.7 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 1.0 0.8 0.0 2.7 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 1.1 24.2 1.3 4.0 1.2 1.8 3.4 7.3 3.0 3.6 3.1 4.3 3.9 3.7 33.3 0.6 2.2 2.1 1.9 1.6 2.0 10.2 3.3 2.9 3.6 3.2 47.1 1.8 0.5 3.5 4.1 3.0 0.0 4.0 1.8 1.5 2.0 5.0 30.8 2.2 2.0 3.5 3.7 1.4 4.1 2.4 10.6 14.0 1.8 6.3 2.1 10.6 17.3 2.1 2.2 2.2 2.6 1.8 1.1 1.9 10.9 18.2 6.6 1.6 2.7 11.6 6.5 1.9 5.3 1.1 1.7 4.0 1.7 1.1 NT5C3A "cN-III, hUMP1, NT5C3, p36, P5'N-1, PN-I, POMP, PSN1, UMPH, UMPH1" ENSG00000122643 "5'-nucleotidase, cytosolic IIIA" Q9H0P0 7 33014114-33062797 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" "Hydrolase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 87.4" "Cell type enhanced" "Detected in all" "Distal enterocytes: 191.0;Paneth cells: 186.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010520, HPA010630, HPA029058" Uncertain Supported "Nucleoplasm,Nuclear bodies,Endoplasmic reticulum,Cytosol" "Intracellular and membrane" NA NA 10000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 51: Myeloid cells - Hemostasis" "Endoplasmic reticulum, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA010520: , HPA010630: AB_2668319, HPA029058: AB_10601380" "unprognostic (7.50e-2)" "unprognostic (3.10e-1)" "unprognostic (1.14e-1)" "unprognostic (2.69e-2)" "unprognostic (1.22e-1)" "unprognostic (5.56e-2)" "prognostic unfavorable (2.42e-4)" "unprognostic (3.25e-2)" "unprognostic (3.12e-2)" "unprognostic (2.82e-3)" "unprognostic (2.08e-2)" "unprognostic (1.98e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (9.37e-2)" "unprognostic (2.05e-1)" "unprognostic (2.12e-3)" "unprognostic (3.43e-3)" 12.4 14.3 11.4 26.1 11.4 32.6 21.3 15.2 15.6 12.6 10.8 51.9 40.0 16.9 14.3 18.6 15.9 23.4 16.6 11.5 11.5 22.4 11.8 17.6 30.8 11.1 11.8 13.4 21.4 9.7 7.5 16.3 11.5 12.3 51.0 20.4 9.7 10.0 87.4 28.7 37.3 13.2 12.7 22.9 27.0 9.5 12.0 22.5 17.1 51.0 45.8 23.8 14.4 13.1 42.2 27.6 25.2 29.6 21.2 16.1 20.3 44.8 30.5 29.2 38.9 19.9 115.1 100.4 27.7 29.6 48.3 63.8 28.3 30.8 40.4 16.2 36.2 54.7 36.5 28.7 23.3 55.6 36.9 21.7 23.8 35.9 63.0 16.4 22.2 33.2 43.3 24.8 37.3 29.9 25.0 87.8 27.8 47.1 31.2 25.9 22.9 60.0 87.8 39.8 28.1 37.0 31.1 52.4 66.6 24.5 35.2 33.5 19.8 25.1 20.9 42.6 55.7 50.6 69.0 54.8 20.6 34.9 42.5 112.5 25.9 82.5 26.6 32.7 30.6 64.0 34.2 30.8 22.1 63.6 34.5 29.1 103.8 28.2 39.2 20.6 56.2 37.9 11.4 11.4 15.2 15.6 11.5 11.5 11.1 11.8 11.5 12.7 12.0 13.1 39.1 22.4 13.7 30.7 85.1 46.8 40.9 85.3 47.8 23.9 22.6 18.9 16.9 32.9 40.4 16.5 41.7 36.9 42.5 191.0 29.4 34.4 5.7 40.9 21.0 40.8 119.6 127.1 45.3 79.0 31.6 35.2 42.8 21.4 17.7 38.3 30.0 18.9 25.0 1.7 49.4 98.9 40.7 31.2 23.5 5.0 33.8 111.4 26.6 29.0 37.0 23.4 55.6 48.2 52.4 48.3 186.6 22.2 43.8 45.7 91.8 84.8 53.7 27.1 13.1 30.7 24.9 46.4 24.0 35.5 38.9 28.3 53.7 23.3 71.0 65.9 OLFM4 "GC1, GW112, OlfD" ENSG00000102837 "Olfactomedin 4" Q6UX06 13 53028813-53052057 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1296.1;pancreas: 671.4" "Cell type enhanced" "Detected in many" "Ductal cells: 497.1;Exocrine glandular cells: 900.9;Intestinal goblet cells: 791.9;Pancreatic endocrine cells: 933.7;Paneth cells: 556.9;Undifferentiated cells: 2419.9;Urothelial cells: 1989.0" "Group enriched" "Detected in many" 14 "colorectal cancer: 711.4;pancreatic cancer: 594.7;stomach cancer: 724.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 5.4;BJ hTERT+: 18.8;HaCaT: 26.4;OE19: 10.4;RPMI-8226: 6.2" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA077718 Enhanced Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge,Cytosol" "Secreted to digestive system" Yes NA 9300 "Cluster 56: Intestine - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane" "Cytokinetic bridge, Cytosol" "HPA077718: AB_2732358" "prognostic favorable (8.77e-4)" "unprognostic (4.84e-2)" "unprognostic (1.65e-3)" "unprognostic (2.33e-1)" "unprognostic (7.24e-2)" "unprognostic (1.34e-1)" "unprognostic (3.74e-2)" "unprognostic (5.16e-2)" "unprognostic (1.40e-1)" "unprognostic (1.22e-1)" "unprognostic (4.78e-2)" "unprognostic (1.28e-1)" "unprognostic (1.50e-1)" "unprognostic (1.29e-2)" "unprognostic (1.33e-1)" "unprognostic (4.37e-2)" "unprognostic (4.84e-3)" 1.9 0.1 0.2 195.4 0.5 126.0 6.8 0.1 0.5 7.9 0.2 451.6 1211.9 5.5 3.5 0.8 8.3 10.4 0.8 0.2 0.4 26.9 0.9 3.8 1.4 0.1 0.2 0.2 671.4 0.0 0.5 0.6 0.2 92.4 568.7 0.4 16.2 0.9 0.6 0.4 1296.1 52.6 0.2 18.0 16.1 0.3 0.2 4.2 0.4 2.1 0.2 127.0 285.6 0.2 0.0 0.0 0.1 0.0 0.0 0.0 5.4 2.4 18.8 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 26.4 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.0 0.0 10.4 0.0 0.0 0.8 6.2 0.2 0.0 1.1 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.6 0.9 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.1 0.5 0.2 0.4 0.1 0.2 0.2 0.2 0.2 0.2 0.2 0.0 0.0 0.3 3.8 0.1 168.5 0.3 0.0 0.0 9.8 2.5 0.5 0.0 11.9 139.8 0.0 0.0 0.0 98.7 1.9 497.1 0.2 13.5 0.5 1.4 92.3 0.8 1.0 900.9 0.0 1.5 0.0 17.6 0.0 0.0 0.0 0.0 0.1 0.0 0.3 791.9 2.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 10.3 4.0 0.0 0.0 0.2 933.7 556.9 0.0 0.4 209.4 300.6 0.0 0.5 0.2 0.0 2.1 9.2 0.0 0.1 0.0 0.0 0.0 3.1 0.2 2419.9 1989.0 OPN1SW "BCP, BOP, CBT" ENSG00000128617 "Opsin 1, short wave sensitive" P03999 7 128772485-128775794 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Sensory transduction, Vision" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 84 "retina: 41.0" "Cell type enriched" "Detected in some" 12 "Cone photoreceptor cells: 41.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "LHCN-M2: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA013562, HPA014083" Enhanced Approved "Nucleoplasm,Nuclear bodies,Cytokinetic bridge,Cytosol" Yes NA "Cluster 79: Retina - Phototransduction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "Nuclear bodies, Cytokinetic bridge, Cytosol" "HPA013562: AB_2668850, HPA014083: AB_2668938" "unprognostic (2.88e-1)" "unprognostic (5.17e-2)" "unprognostic (2.22e-2)" "unprognostic (1.33e-2)" "unprognostic (2.55e-2)" "unprognostic (2.16e-1)" "prognostic unfavorable (8.50e-5)" "unprognostic (1.13e-1)" "unprognostic (1.27e-1)" "unprognostic (6.33e-2)" "unprognostic (3.79e-1)" "unprognostic (6.05e-2)" "prognostic unfavorable (2.26e-8)" "prognostic unfavorable (5.98e-8)" "unprognostic (2.53e-1)" "unprognostic (8.99e-2)" "prognostic unfavorable (9.33e-4)" 0.2 0.1 0.1 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.2 0.4 0.0 0.4 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 41.0 0.2 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.4 0.0 0.0 0.0 41.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 P3H2 "FLJ10718, LEPREL1, MLAT4" ENSG00000090530 "Prolyl 3-hydroxylase 2" Q8IVL5 3 189956728-190122437 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 80.3;Granulosa cells: 124.1;Microglial cells: 91.8;Theca cells: 74.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 22 "plasmacytoid DC: 28.9" "Lineage enriched" "Detected in single" 90 "dendritic cells: 28.9" "Cell line enhanced" "Detected in many" "GAMG: 120.2;HaCaT: 109.9;RPTEC TERT1: 109.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007890, HPA013355, HPA013611" Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles,Cytosol" "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus" "Nucleoplasm, Vesicles, Cytosol" "HPA007890: AB_1852796, HPA013355: AB_1852798, HPA013611: " "unprognostic (4.90e-2)" "unprognostic (1.57e-1)" "unprognostic (3.76e-1)" "unprognostic (4.32e-3)" "unprognostic (1.97e-2)" "unprognostic (7.75e-2)" "unprognostic (9.68e-2)" "unprognostic (2.17e-1)" "unprognostic (3.15e-1)" "unprognostic (1.19e-1)" "unprognostic (1.03e-3)" "unprognostic (1.60e-1)" "unprognostic (1.15e-2)" "unprognostic (1.80e-2)" "unprognostic (1.48e-1)" "unprognostic (1.10e-1)" "unprognostic (4.01e-2)" 4.9 41.6 2.8 4.9 3.1 1.0 6.5 3.0 3.1 17.0 1.8 24.0 2.7 17.6 18.5 11.0 8.0 4.8 8.8 3.3 4.8 51.3 7.0 28.7 2.4 7.6 4.7 16.1 3.6 2.3 8.2 9.2 6.7 37.6 10.4 19.3 4.9 26.5 1.2 17.8 6.7 32.4 5.2 54.8 23.9 4.2 4.9 5.2 3.0 1.7 2.0 11.9 19.9 8.3 46.9 18.2 35.1 0.2 0.6 1.4 42.1 48.7 19.3 7.8 12.6 15.0 18.0 0.1 27.1 8.6 120.2 109.9 0.1 65.3 16.3 0.4 6.2 0.1 12.1 0.3 35.4 0.2 0.3 16.9 21.4 15.2 5.4 73.5 1.4 0.1 0.1 0.4 12.3 1.1 0.1 0.4 11.0 31.3 3.7 0.1 7.1 2.8 109.8 77.5 2.5 0.3 66.1 3.7 29.3 51.1 0.1 0.7 24.4 45.9 16.8 0.4 8.9 3.4 0.2 0.5 10.6 0.2 60.2 0.3 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.2 0.1 0.0 28.9 0.0 0.2 2.8 3.1 3.0 3.1 3.3 4.8 7.6 4.7 6.7 5.2 4.9 8.3 5.7 48.1 80.3 19.2 1.0 0.0 7.7 0.0 13.6 2.3 1.6 9.9 1.0 2.8 3.1 44.1 4.2 42.0 9.5 19.8 5.9 4.7 19.6 2.0 27.3 10.5 0.0 2.7 55.6 0.8 14.7 10.3 8.6 1.5 1.3 124.1 32.5 0.8 11.4 10.1 60.4 0.5 0.0 3.2 0.0 14.9 4.7 5.6 0.0 91.8 0.8 44.5 0.0 43.7 4.4 30.6 1.9 0.0 0.2 15.1 0.0 26.2 0.0 1.2 0.0 10.9 45.2 0.5 0.9 13.5 0.0 38.6 0.7 74.3 2.1 3.9 PAX5 BSAP ENSG00000196092 "Paired box 5" Q02548 9 36833269-37034268 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Spermatogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "lymphoid tissue: 39.7" "Cell type enriched" "Detected in some" 29 "B-cells: 91.3" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "midbrain: 6.5" "Group enriched" "Detected in some" 43 "memory B-cell: 39.0;naive B-cell: 26.0" "Lineage enriched" "Detected in single" 52 "B-cells: 39.0" "Group enriched" "Detected in some" 9 "Daudi: 66.6;REH: 194.1;U-698: 87.1" "Region enriched" "Detected in single" 11 "midbrain: 3.9" "Low region specificity" "Detected in all" "CAB026269, CAB026869, HPA056394, HPA068498" Enhanced Supported Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 57: B-cells - Immune response" Nucleoplasm "Nucleoli fibrillar center, Vesicles, Cytosol" "CAB026269: , CAB026869: , HPA056394: AB_2683116, HPA068498: AB_2685997" "unprognostic (4.69e-4)" "unprognostic (3.83e-1)" "unprognostic (9.13e-2)" "unprognostic (1.42e-1)" "unprognostic (2.65e-2)" "unprognostic (1.15e-1)" "unprognostic (2.09e-2)" "unprognostic (2.95e-2)" "unprognostic (2.48e-1)" "unprognostic (2.00e-2)" "unprognostic (1.03e-1)" "unprognostic (2.46e-2)" "unprognostic (1.11e-3)" "unprognostic (3.15e-1)" "unprognostic (8.96e-2)" "unprognostic (6.03e-2)" "unprognostic (1.01e-1)" 0.3 0.1 0.4 14.9 0.3 9.4 0.1 0.5 0.5 0.0 0.2 0.8 0.5 0.2 0.1 0.2 0.0 0.8 0.2 0.3 0.6 0.1 0.2 0.3 39.7 1.1 6.5 0.0 0.0 0.0 0.2 0.1 4.1 0.3 0.8 0.5 1.0 0.0 3.1 0.0 6.6 0.0 0.8 18.7 1.6 0.6 1.9 2.8 0.2 0.0 36.2 1.1 0.0 0.3 0.1 0.3 5.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 66.6 0.1 0.0 0.1 0.2 0.1 0.0 0.0 3.5 0.1 0.0 0.0 0.0 0.0 2.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.5 0.1 0.3 1.9 0.3 0.4 194.1 0.4 0.3 0.0 0.0 13.2 2.9 0.1 0.7 0.0 0.0 0.0 7.5 0.2 0.0 0.2 0.1 0.0 0.2 0.1 87.1 0.0 1.5 0.1 0.7 0.0 0.1 0.0 0.1 0.1 39.0 0.0 0.0 0.1 26.0 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.7 0.4 0.3 0.5 0.5 0.3 0.6 1.1 6.5 4.1 0.8 1.9 0.3 0.0 0.0 0.0 0.7 91.3 0.0 0.3 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.3 0.0 0.4 0.6 0.0 0.0 0.4 0.0 0.0 1.3 0.0 0.0 0.4 0.0 0.0 0.5 0.1 0.0 0.3 0.0 3.1 0.0 0.9 0.0 0.0 0.2 0.5 0.0 0.0 0.3 0.0 0.1 0.0 2.7 0.4 0.0 0.1 0.0 0.1 0.0 0.8 0.1 0.6 0.2 0.2 0.0 0.0 2.0 0.0 0.0 0.3 PCDHGA1 PCDH-GAMMA-A1 ENSG00000204956 "Protocadherin gamma subfamily A, 1" Q9Y5H4 5 141330571-141512981 "Predicted membrane proteins" "Cell adhesion" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 3.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Bipolar cells: 2.4;Cardiomyocytes: 1.8;Horizontal cells: 3.3" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "LHCN-M2: 4.5;T-47d: 7.3;WM-115: 3.3" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA036547" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 6: T47d - Mammary gland" "Cluster 37: Myocytes - Muscle contraction" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA036547: AB_10669798" "unprognostic (9.50e-4)" "unprognostic (2.39e-2)" "unprognostic (9.88e-2)" "unprognostic (4.42e-3)" "unprognostic (3.39e-1)" "unprognostic (3.97e-2)" "unprognostic (2.42e-1)" "unprognostic (5.61e-3)" "unprognostic (1.70e-2)" "unprognostic (6.89e-2)" "unprognostic (2.86e-1)" "unprognostic (1.03e-1)" "unprognostic (1.07e-3)" "unprognostic (4.76e-2)" "unprognostic (1.38e-1)" "unprognostic (2.73e-2)" "unprognostic (1.45e-3)" 0.3 0.2 1.1 0.2 2.3 0.2 0.2 3.2 2.0 0.5 0.0 0.5 0.2 0.6 0.9 0.2 0.4 0.1 1.2 2.2 0.9 0.2 0.1 0.3 0.1 1.5 1.4 0.6 0.5 0.5 0.9 0.5 0.9 0.3 0.2 1.0 0.2 0.2 0.7 0.3 0.1 0.4 1.7 0.2 0.1 0.7 1.4 0.1 0.2 0.4 0.1 0.4 0.3 1.3 0.0 0.2 0.3 1.1 0.7 1.3 0.1 1.1 0.7 0.3 0.6 0.3 0.1 0.2 1.8 0.7 0.5 0.1 0.1 0.2 0.7 0.1 0.1 0.1 0.2 0.1 0.2 0.0 0.1 1.1 0.3 0.0 0.4 2.1 0.0 0.1 0.1 0.5 4.5 0.0 0.1 0.5 0.1 0.0 0.2 2.0 1.6 0.2 0.2 0.2 1.0 1.3 0.1 0.6 1.1 0.3 7.3 0.2 0.5 2.0 0.3 1.0 0.2 0.1 0.6 0.1 2.4 0.1 3.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.1 2.3 3.2 2.0 2.2 0.9 1.5 1.4 0.9 1.7 1.4 1.3 0.3 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.1 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 3.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.7 0.3 0.1 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.0 PCDHGA10 PCDH-GAMMA-A10 ENSG00000253846 "Protocadherin gamma subfamily A, 10" Q9Y5H3 5 141412987-141512979 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 27.7;Cone photoreceptor cells: 16.7;Horizontal cells: 23.5;Skeletal myocytes: 14.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 14.6;HSkMC: 16.1;T-47d: 19.7;U-2197: 11.6" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA077276" Approved Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 6: T47d - Mammary gland" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nucleoplasm, Vesicles, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA077276: " "unprognostic (2.92e-1)" "unprognostic (2.17e-4)" "unprognostic (1.63e-1)" "unprognostic (3.33e-2)" "unprognostic (1.12e-1)" "unprognostic (3.05e-2)" "unprognostic (9.99e-2)" "unprognostic (1.06e-2)" "unprognostic (2.01e-1)" "unprognostic (2.02e-1)" "unprognostic (4.39e-2)" "unprognostic (2.03e-2)" "unprognostic (2.64e-3)" "unprognostic (2.32e-3)" "unprognostic (1.34e-1)" "unprognostic (2.06e-1)" "unprognostic (8.83e-3)" 1.6 1.6 3.5 0.4 3.2 0.1 1.1 4.1 2.4 1.3 0.8 1.0 0.8 1.3 0.7 1.7 1.3 1.4 1.0 2.7 3.8 0.5 1.5 1.3 0.4 3.3 3.1 1.3 0.6 2.1 0.8 3.6 3.4 1.4 0.9 2.5 1.8 1.8 1.1 2.0 1.0 1.1 4.2 0.9 2.0 0.5 3.9 0.4 2.1 0.3 0.5 0.8 1.3 3.8 0.0 0.0 14.6 7.5 6.3 2.7 6.9 2.6 0.1 3.6 5.6 0.3 0.9 0.8 9.6 3.7 0.2 0.4 3.5 2.4 2.8 0.9 0.1 0.0 0.3 0.0 2.5 1.5 0.3 16.1 0.4 2.4 1.0 0.4 1.4 0.3 0.0 0.1 9.0 0.1 0.1 0.4 1.4 0.0 0.1 0.2 1.2 0.0 2.4 0.1 2.0 0.7 0.4 0.1 0.4 3.5 19.7 1.9 3.3 6.7 0.4 11.6 0.1 0.2 1.2 0.1 3.4 0.0 0.4 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.5 3.2 4.1 2.4 2.7 3.8 3.3 3.1 3.4 4.2 3.9 3.8 5.8 0.0 2.0 0.0 0.9 0.1 2.3 0.6 1.2 27.7 2.2 2.2 3.4 1.5 1.6 1.8 16.7 2.1 1.3 0.7 0.0 1.0 0.0 1.3 7.7 4.8 1.2 0.4 0.0 1.4 1.3 4.8 1.5 2.0 1.3 1.0 4.6 1.7 1.0 23.5 0.0 1.6 0.0 0.0 0.0 0.2 3.4 0.7 1.8 0.0 0.0 5.7 0.0 0.0 0.0 3.1 0.4 2.2 0.5 2.8 0.4 0.5 0.0 6.7 6.6 14.9 3.7 0.4 0.7 1.2 0.4 0.4 0.5 3.0 1.3 1.5 PCDHGA11 PCDH-GAMMA-A11 ENSG00000253873 "Protocadherin gamma subfamily A, 11" Q9Y5H2 5 141421047-141512975 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.1;Bipolar cells: 2.5;Hepatic stellate cells: 1.1;Horizontal cells: 1.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 24.3;ASC TERT1: 25.9;GAMG: 47.4;hTERT-RPE1: 69.8;WM-115: 43.9" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nucleoplasm, Vesicles, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (3.13e-2)" "unprognostic (1.78e-3)" "unprognostic (9.13e-2)" "unprognostic (1.15e-2)" "unprognostic (1.68e-2)" "unprognostic (2.62e-1)" "unprognostic (2.70e-2)" "unprognostic (1.16e-3)" "unprognostic (1.09e-1)" "unprognostic (1.95e-2)" "unprognostic (2.97e-1)" "unprognostic (2.22e-1)" "unprognostic (3.03e-2)" "unprognostic (3.74e-2)" "unprognostic (3.54e-1)" "unprognostic (4.34e-3)" "unprognostic (1.89e-1)" 0.8 0.7 1.4 0.7 1.8 0.0 0.6 5.1 1.3 0.8 0.7 1.0 0.2 0.7 0.3 0.7 0.9 0.5 1.6 2.1 2.3 0.5 0.4 0.6 0.4 1.8 1.2 1.1 0.5 0.3 0.6 2.2 2.1 0.5 0.3 3.1 0.7 0.7 1.1 1.7 0.4 0.8 2.4 0.3 0.4 0.8 1.9 0.3 0.8 0.5 0.3 0.6 0.8 2.9 0.0 0.0 0.7 2.4 24.3 25.9 0.9 5.5 10.6 4.2 6.6 0.1 0.2 0.6 9.1 5.6 47.4 3.7 0.1 0.6 6.6 0.2 2.4 0.1 0.1 0.0 4.0 0.4 0.0 19.0 0.3 7.4 0.1 69.8 6.5 1.2 0.0 0.1 0.1 0.0 0.0 0.3 2.9 0.0 0.1 17.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 21.3 9.9 0.5 3.2 7.9 0.8 0.1 0.6 0.1 0.0 0.4 0.0 0.1 0.0 43.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.4 1.8 5.1 1.3 2.1 2.3 1.8 1.2 2.1 2.4 1.9 2.9 0.5 0.0 1.1 0.0 0.0 0.0 0.2 0.0 0.0 2.5 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.7 0.1 0.5 0.8 0.0 0.0 0.0 0.2 0.3 0.5 0.0 0.1 0.0 0.2 1.1 0.0 0.4 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.4 0.0 0.3 0.0 0.1 0.0 0.6 0.0 0.6 0.3 0.1 0.1 0.7 0.0 0.1 0.0 0.2 0.1 0.1 PCDHGA12 "CDH21, FIB3, KIAA0588, PCDH-GAMMA-A12" ENSG00000253159 "Protocadherin gamma subfamily A, 12" O60330 5 141430507-141512975 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.0" "Cell type enhanced" "Detected in some" "Adipocytes: 2.2;Bipolar cells: 3.8;Cardiomyocytes: 1.6;Endometrial stromal cells: 2.3;Endothelial cells: 2.2;Fibroblasts: 3.2;Skeletal myocytes: 2.0" "Group enriched" "Detected in many" 5 "glioma: 1.7;melanoma: 5.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "memory B-cell: 1.2" "Lineage enriched" "Detected in single" 4 "B-cells: 1.2" "Cell line enhanced" "Detected in some" "BJ: 9.3;BJ hTERT+: 15.4;fHDF/TERT166: 23.3;HHSteC: 7.2;HSkMC: 16.5;TIME: 7.5" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA 21000 "Cluster 37: B-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (3.17e-3)" "unprognostic (2.71e-2)" "unprognostic (1.04e-2)" "unprognostic (2.67e-1)" "unprognostic (2.74e-1)" "unprognostic (5.06e-2)" "unprognostic (1.99e-1)" "unprognostic (9.01e-3)" "unprognostic (1.19e-1)" "unprognostic (4.65e-4)" "unprognostic (2.98e-1)" "unprognostic (3.02e-1)" "unprognostic (1.28e-4)" "unprognostic (8.30e-3)" "unprognostic (1.57e-1)" "unprognostic (2.42e-1)" "unprognostic (6.85e-3)" 3.0 4.3 5.3 0.8 6.8 0.0 1.5 5.5 3.7 2.0 0.8 1.3 0.2 2.6 0.4 1.0 1.9 3.9 4.2 5.1 8.4 1.0 0.7 3.1 0.4 10.0 4.2 1.9 1.1 0.3 1.4 2.2 4.5 1.0 0.3 1.4 0.9 1.5 1.3 1.7 0.8 1.7 5.5 1.2 1.0 0.3 5.2 0.9 1.6 1.1 0.4 1.2 2.0 4.6 0.0 0.0 0.1 1.9 0.8 1.4 0.1 9.3 15.4 0.0 0.0 0.0 0.0 0.5 0.0 23.3 0.1 2.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 7.2 0.0 0.0 16.5 0.0 4.5 0.0 0.0 5.4 0.0 0.0 0.0 3.2 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 2.6 7.5 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 5.3 6.8 5.5 3.7 5.1 8.4 10.0 4.2 4.5 5.5 5.2 4.6 2.2 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 3.8 0.2 0.6 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 2.3 2.2 0.0 0.0 0.0 0.2 0.0 3.2 1.1 0.1 0.0 0.1 0.7 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.3 0.0 0.0 0.0 0.7 0.0 2.0 1.0 0.0 0.0 0.4 0.0 0.0 0.1 0.7 0.0 0.0 PCDHGA2 PCDH-GAMMA-A2 ENSG00000081853 "Protocadherin gamma subfamily A, 2" Q9Y5H1 5 141338760-141512975 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 1.2;Bipolar cells: 3.2;Cardiomyocytes: 1.8;Fibroblasts: 1.5;Leydig cells: 1.2;Peritubular cells: 2.6;Skeletal myocytes: 1.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 6.4;BJ: 3.9;fHDF/TERT166: 4.4;HSkMC: 3.4;hTERT-RPE1: 3.9" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA038625" Approved Approved "Nucleoplasm,Nucleoli,Vesicles,Plasma membrane,Focal adhesion sites,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Nucleoli, Focal adhesion sites, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA038625: AB_2732480" "unprognostic (2.43e-3)" "unprognostic (2.10e-2)" "unprognostic (1.32e-2)" "unprognostic (4.54e-1)" "unprognostic (2.92e-1)" "unprognostic (1.14e-1)" "unprognostic (3.01e-1)" "unprognostic (2.82e-1)" "unprognostic (1.56e-1)" "unprognostic (1.18e-1)" "unprognostic (9.01e-2)" "unprognostic (4.32e-2)" "unprognostic (8.45e-3)" "unprognostic (9.68e-3)" "unprognostic (1.04e-2)" "unprognostic (1.18e-2)" "unprognostic (2.23e-4)" 2.2 1.6 1.8 0.7 1.4 0.0 1.9 2.7 2.5 3.0 0.7 1.5 0.1 2.9 1.9 0.8 3.1 1.4 4.9 2.9 1.5 1.1 0.7 2.0 0.2 3.8 3.2 6.3 1.8 3.8 2.6 0.7 2.6 1.9 0.3 2.3 1.2 2.2 1.0 1.0 0.6 2.1 3.5 0.6 0.9 2.3 2.6 0.8 1.6 1.1 0.2 1.4 1.7 2.2 0.0 0.7 0.3 0.2 2.8 6.4 0.0 3.9 1.3 0.3 0.5 0.0 0.0 0.1 0.4 4.4 0.5 0.1 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 3.4 0.1 0.0 0.2 3.9 1.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.1 0.5 0.0 0.2 0.5 0.0 2.3 0.1 0.3 0.4 0.0 2.3 0.6 0.3 0.2 0.0 0.0 0.3 0.0 1.5 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.4 2.7 2.5 2.9 1.5 3.8 3.2 2.6 3.5 2.6 2.2 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 3.2 0.3 0.9 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 1.1 0.9 0.0 0.0 0.0 0.2 0.0 1.5 0.0 0.1 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 2.6 0.0 0.0 0.0 0.4 0.0 0.4 0.0 1.5 0.5 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 PCDHGA3 PCDH-GAMMA-A3 ENSG00000254245 "Protocadherin gamma subfamily A, 3" Q9Y5H0 5 141343829-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 2.4;Cardiomyocytes: 1.6;Endometrial stromal cells: 1.9;Fibroblasts: 1.3;Horizontal cells: 3.3;Skeletal myocytes: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 7.1;BJ: 2.3;EFO-21: 5.7" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (6.47e-2)" "unprognostic (4.79e-2)" "unprognostic (1.48e-2)" "unprognostic (1.64e-1)" "unprognostic (4.53e-2)" "unprognostic (1.03e-1)" "unprognostic (2.35e-1)" "unprognostic (1.85e-1)" "unprognostic (7.44e-2)" "unprognostic (1.08e-1)" "unprognostic (1.28e-1)" "unprognostic (3.17e-2)" "unprognostic (2.43e-1)" "unprognostic (2.32e-3)" "unprognostic (7.12e-3)" "unprognostic (3.31e-2)" "unprognostic (2.52e-4)" 1.2 1.2 2.6 0.2 1.7 0.0 0.9 2.2 2.6 1.6 0.1 0.7 0.0 1.4 0.9 0.2 1.2 0.9 3.7 2.5 1.8 0.5 0.6 0.9 0.0 3.8 2.9 2.5 0.9 0.6 1.2 1.7 2.2 0.7 0.2 1.8 0.7 0.8 0.8 0.5 0.2 0.9 3.4 0.2 0.4 1.5 2.9 0.2 0.8 0.9 0.1 0.8 0.9 2.5 0.0 0.0 7.1 0.0 0.0 0.9 0.0 2.3 0.2 0.0 0.0 0.0 0.0 0.0 5.7 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.3 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 1.7 2.2 2.6 2.5 1.8 3.8 2.9 2.2 3.4 2.9 2.5 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.4 0.1 0.5 1.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 1.9 0.9 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 3.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 1.6 0.9 0.1 0.5 0.0 0.0 0.1 0.0 0.4 0.0 0.0 PCDHGA4 PCDH-GAMMA-A4 ENSG00000262576 "Protocadherin gamma subfamily A, 4" Q9Y5G9 5 141355021-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.0;Skeletal myocytes: 1.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 7.4;BJ: 4.3;HSkMC: 4.3;HUVEC TERT2: 4.3;U-87 MG: 6.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (1.27e-2)" "unprognostic (4.55e-3)" "unprognostic (2.00e-2)" "unprognostic (6.54e-4)" "unprognostic (1.87e-2)" "unprognostic (1.06e-2)" "unprognostic (1.02e-1)" "unprognostic (1.20e-2)" "unprognostic (5.62e-2)" "unprognostic (3.76e-1)" "unprognostic (6.31e-2)" "unprognostic (1.74e-1)" "unprognostic (2.94e-2)" "unprognostic (1.30e-2)" "unprognostic (2.30e-2)" "unprognostic (1.65e-1)" "unprognostic (2.31e-4)" 1.7 1.3 1.6 0.4 1.8 0.0 0.9 3.7 1.7 1.3 0.0 0.9 0.2 1.6 0.8 0.4 0.9 0.8 1.5 2.9 1.5 0.4 0.3 1.0 0.1 2.1 2.4 1.6 2.1 2.3 1.0 0.8 1.7 1.1 0.3 1.5 0.8 1.1 0.7 0.5 0.3 1.5 2.0 0.3 0.4 0.7 2.1 0.2 0.7 1.0 0.1 0.7 0.8 2.5 0.0 0.1 0.8 0.4 3.3 7.4 0.0 4.3 3.4 0.2 0.8 0.0 0.1 0.7 1.4 3.7 1.3 0.0 0.1 0.1 0.4 0.0 0.3 0.0 0.0 0.0 1.3 0.0 0.3 4.3 0.1 0.0 0.0 2.6 4.3 0.0 0.1 0.2 1.8 0.6 0.2 0.2 0.1 0.0 0.2 0.3 1.2 0.1 0.2 0.0 0.6 1.3 0.2 0.2 0.9 0.3 1.6 0.0 2.8 1.8 0.5 2.4 0.3 0.1 0.2 0.1 6.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.8 3.7 1.7 2.9 1.5 2.1 2.4 1.7 2.0 2.1 2.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 PCDHGA5 "CDH-GAMMA-A5, ME3, PCDH-GAMMA-A5" ENSG00000253485 "Protocadherin gamma subfamily A, 5" Q9Y5G8 5 141364232-141512979 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 4.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 11.5;Endometrial stromal cells: 9.2;Horizontal cells: 10.1;Sertoli cells: 6.6;Skeletal myocytes: 5.7" "Cancer enhanced" "Detected in single" "prostate cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "ASC diff: 15.8;ASC TERT1: 6.2" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (3.61e-2)" "unprognostic (1.04e-2)" "unprognostic (5.28e-2)" "unprognostic (4.83e-1)" "unprognostic (6.60e-3)" "unprognostic (5.71e-2)" "unprognostic (8.46e-2)" "unprognostic (6.53e-3)" "unprognostic (4.07e-1)" "unprognostic (9.40e-2)" "unprognostic (1.38e-1)" "unprognostic (1.05e-1)" "unprognostic (1.12e-1)" "unprognostic (5.90e-2)" "unprognostic (3.93e-2)" "unprognostic (1.55e-2)" "unprognostic (8.38e-4)" 1.0 0.6 1.0 0.3 1.6 0.1 1.2 4.9 1.1 2.5 0.0 1.1 0.1 2.0 0.6 0.8 1.4 1.1 1.9 1.2 1.2 0.3 0.2 1.1 0.2 2.2 2.1 2.0 0.6 0.6 0.9 0.6 1.0 1.4 0.3 1.2 0.8 0.9 0.6 0.7 0.4 1.0 1.2 0.2 0.5 0.3 1.2 0.3 0.5 0.7 0.1 1.0 1.3 2.0 0.0 0.4 0.2 0.1 15.8 6.2 0.0 0.7 0.1 0.1 0.3 0.0 0.0 0.8 0.3 0.3 0.8 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.2 0.1 0.1 0.1 0.0 1.5 0.2 0.0 0.0 0.4 0.5 0.0 0.1 0.5 0.6 0.3 0.5 0.6 0.1 0.0 0.3 0.8 0.6 0.1 0.0 0.0 0.2 0.2 0.0 0.2 0.3 0.2 1.4 0.0 0.9 0.5 0.1 0.9 0.6 0.1 0.9 0.1 0.3 0.1 0.7 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.2 0.0 0.1 0.0 0.0 1.0 1.6 4.9 1.1 1.2 1.2 2.2 2.1 1.0 1.2 1.2 2.0 1.8 0.0 1.1 0.0 0.2 0.1 0.8 0.1 0.6 11.5 0.3 0.4 2.6 0.0 0.7 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.1 0.4 9.2 1.9 0.0 0.0 0.0 0.2 0.0 4.0 0.0 0.2 1.3 0.6 1.4 0.3 0.1 10.1 0.0 0.0 0.0 0.3 0.0 0.0 3.7 0.4 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.2 0.0 1.9 0.0 0.5 0.0 0.1 0.1 1.3 6.6 5.7 1.7 0.0 0.3 0.3 0.0 0.0 0.6 0.9 0.0 0.4 PCDHGA6 PCDH-GAMMA-A6 ENSG00000253731 "Protocadherin gamma subfamily A, 6" Q9Y5G7 5 141373891-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 10.6;Cardiomyocytes: 5.0;Endometrial stromal cells: 4.6;Hepatic stellate cells: 3.6;Skeletal myocytes: 5.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SCLC-21H: 9.6;T-47d: 5.6;WM-115: 12.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (4.49e-2)" "unprognostic (8.91e-3)" "unprognostic (5.45e-2)" "unprognostic (1.43e-1)" "unprognostic (1.15e-1)" "unprognostic (1.49e-2)" "unprognostic (1.16e-1)" "unprognostic (1.18e-1)" "unprognostic (1.25e-1)" "unprognostic (2.07e-2)" "unprognostic (3.86e-3)" "unprognostic (2.02e-2)" "unprognostic (5.26e-2)" "unprognostic (7.44e-2)" "unprognostic (5.21e-2)" "unprognostic (1.11e-1)" "unprognostic (4.19e-3)" 1.4 1.1 1.6 0.7 1.8 0.1 1.3 7.2 1.6 2.7 0.0 2.0 0.2 3.2 1.4 0.8 2.0 1.1 2.7 1.7 1.8 0.8 0.5 1.5 0.4 1.8 1.7 3.5 1.2 1.1 1.8 2.3 0.9 1.2 0.4 2.0 1.5 1.6 0.9 1.5 0.8 2.0 0.8 0.9 0.7 0.8 2.0 0.5 1.2 1.0 0.4 1.6 1.5 1.9 0.0 0.3 2.7 0.4 1.3 4.7 0.1 2.1 0.7 1.1 1.1 0.0 0.1 2.0 2.6 3.3 1.0 0.4 0.1 0.4 0.7 0.0 0.2 0.0 0.3 0.2 0.7 0.1 0.1 4.9 0.3 0.2 0.1 1.0 1.6 0.1 0.2 1.1 0.3 0.4 0.7 1.7 0.3 0.0 0.1 1.4 0.4 0.0 0.3 0.1 9.6 0.7 0.1 0.3 0.6 0.6 5.6 0.1 4.8 0.7 0.3 0.7 0.7 0.4 1.7 0.4 0.8 0.7 12.2 0.4 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.5 0.1 0.0 0.1 0.0 0.0 1.6 1.8 7.2 1.6 1.7 1.8 1.8 1.7 0.9 0.8 2.0 1.9 2.8 0.0 2.2 0.0 0.4 0.0 0.8 0.0 0.0 10.6 0.3 1.0 5.0 1.5 0.6 0.0 0.0 0.1 0.3 0.0 0.0 0.4 0.5 0.4 4.6 1.8 0.0 0.4 0.0 1.5 0.1 2.2 0.0 0.4 0.0 0.6 3.6 0.7 0.1 1.7 0.0 0.2 0.0 0.3 0.0 0.3 1.2 0.5 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.6 0.1 2.2 1.6 0.4 0.0 0.3 0.7 0.9 0.0 5.2 1.9 0.3 0.3 0.5 0.0 0.3 0.2 0.5 0.2 0.2 PCDHGA7 PCDH-GAMMA-A7 ENSG00000253537 "Protocadherin gamma subfamily A, 7" Q9Y5G6 5 141382739-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 5.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.3;Cardiomyocytes: 1.6;Endometrial stromal cells: 2.2;Skeletal myocytes: 2.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 11.3;BJ hTERT+: 20.8;hTERT-RPE1: 10.9;SH-SY5Y: 18.6;T-47d: 8.1" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (1.00e-2)" "unprognostic (4.73e-3)" "unprognostic (1.42e-1)" "unprognostic (7.49e-2)" "unprognostic (2.10e-1)" "unprognostic (6.85e-2)" "unprognostic (2.61e-1)" "unprognostic (1.50e-1)" "unprognostic (1.85e-1)" "unprognostic (5.78e-2)" "unprognostic (3.72e-2)" "unprognostic (1.66e-1)" "unprognostic (3.56e-1)" "unprognostic (4.21e-3)" "unprognostic (6.30e-2)" "unprognostic (4.99e-2)" "unprognostic (1.42e-3)" 0.5 0.4 1.0 0.2 0.9 0.0 0.6 5.9 1.0 1.2 0.0 1.1 0.1 1.3 1.1 0.5 1.0 0.4 1.5 1.1 0.6 0.6 0.4 0.7 0.1 1.5 1.2 1.5 0.7 2.2 0.8 1.3 0.9 0.9 0.3 1.6 0.8 0.8 0.7 1.0 0.4 0.8 1.0 0.4 0.3 0.5 1.3 0.2 1.9 0.5 0.1 0.9 0.7 1.5 0.0 1.6 2.3 0.0 6.6 11.3 0.0 3.3 20.8 4.2 6.1 0.0 0.0 0.5 5.2 0.7 0.2 0.2 0.0 0.1 3.4 0.0 0.3 0.0 0.4 0.2 1.1 0.0 0.0 5.0 0.1 0.0 0.7 10.9 1.7 0.0 0.0 0.1 0.1 0.1 0.6 0.3 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.4 18.6 0.0 0.1 0.1 3.7 8.1 0.0 6.7 0.1 0.1 3.1 0.1 0.1 1.9 0.0 0.5 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.9 5.9 1.0 1.1 0.6 1.5 1.2 0.9 1.0 1.3 1.5 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 4.3 0.3 0.3 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.2 2.2 0.5 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.6 0.0 2.8 0.9 0.0 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.3 PCDHGA8 "KIAA0327, PCDH-GAMMA-A8" ENSG00000253767 "Protocadherin gamma subfamily A, 8" Q9Y5G5 5 141390157-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 7 "brain: 3.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 11.4;Cardiomyocytes: 3.5;Horizontal cells: 3.3;Skeletal myocytes: 5.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (3.28e-2)" "unprognostic (2.27e-2)" "unprognostic (4.86e-2)" "unprognostic (3.38e-2)" "unprognostic (2.80e-1)" "unprognostic (4.10e-2)" "unprognostic (7.68e-2)" "unprognostic (2.30e-2)" "unprognostic (1.83e-2)" "unprognostic (2.23e-1)" "unprognostic (1.24e-1)" "unprognostic (1.35e-2)" "unprognostic (1.49e-3)" "unprognostic (7.59e-2)" "unprognostic (3.92e-2)" "unprognostic (3.38e-1)" "unprognostic (1.99e-3)" 0.1 0.1 0.6 0.1 0.6 0.4 0.1 3.9 0.8 0.2 0.2 0.1 0.0 0.2 0.2 0.1 0.1 0.1 0.5 0.8 0.5 0.0 0.1 0.1 0.1 1.1 0.7 0.3 0.1 0.0 0.2 0.2 0.7 0.1 0.1 0.5 0.1 0.0 0.3 0.3 0.1 0.1 0.3 0.1 0.1 0.1 0.9 0.1 0.4 0.1 0.1 0.1 0.1 1.2 0.0 0.0 0.3 0.1 0.2 0.6 0.1 0.6 0.4 0.4 0.1 0.0 0.1 0.3 0.2 0.4 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.6 0.2 0.4 0.6 0.6 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.7 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.6 0.6 3.9 0.8 0.8 0.5 1.1 0.7 0.7 0.3 0.9 1.2 1.2 0.0 0.6 0.0 0.1 0.0 0.9 0.0 0.0 11.4 0.3 0.3 3.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.6 0.1 2.1 1.2 0.0 0.0 0.0 0.6 0.0 1.1 0.0 0.2 0.0 0.3 0.4 0.7 0.1 3.3 0.0 0.0 0.0 0.3 0.0 0.0 2.1 0.2 0.0 0.0 0.0 1.3 1.0 0.0 0.0 0.1 0.1 1.5 0.0 0.7 0.0 0.2 0.0 1.7 0.0 5.2 0.9 0.7 1.1 0.0 0.0 0.0 0.1 0.5 0.0 0.5 PCDHGA9 PCDH-GAMMA-A9 ENSG00000261934 "Protocadherin gamma subfamily A, 9" Q9Y5G4 5 141402932-141512979 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 6.6" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.5;Cardiomyocytes: 1.3;Endometrial stromal cells: 1.5;Horizontal cells: 3.3;Skeletal myocytes: 2.3" "Cancer enhanced" "Detected in some" "glioma: 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 3.6;HSkMC: 4.0;hTERT-RPE1: 16.9;TIME: 4.6;U-87 MG: 5.1" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (1.98e-2)" "unprognostic (7.47e-3)" "unprognostic (9.86e-3)" "unprognostic (2.22e-1)" "unprognostic (4.68e-2)" "unprognostic (4.96e-2)" "unprognostic (1.61e-1)" "unprognostic (2.15e-1)" "unprognostic (2.39e-1)" "unprognostic (1.87e-3)" "unprognostic (2.26e-1)" "unprognostic (1.79e-1)" "unprognostic (4.48e-3)" "unprognostic (1.94e-2)" "unprognostic (8.83e-2)" "unprognostic (2.71e-1)" "unprognostic (1.83e-2)" 1.8 1.6 3.3 0.7 3.5 0.1 1.3 6.6 3.2 2.0 0.4 1.2 0.5 2.5 1.1 1.4 1.9 2.0 1.1 3.7 2.6 0.8 0.4 1.5 0.5 3.6 3.4 2.8 0.8 1.1 0.9 1.0 3.8 1.5 0.7 4.4 1.1 2.2 0.8 1.7 0.6 1.8 3.7 1.1 0.8 0.4 3.6 0.5 1.4 1.2 0.7 1.2 1.4 5.7 0.0 0.1 0.6 1.6 0.1 0.2 0.2 0.7 0.0 0.6 0.6 0.2 0.4 1.3 3.6 2.0 0.3 0.1 0.1 0.2 0.7 0.0 0.3 0.0 0.1 0.0 1.1 0.0 0.2 4.0 0.1 0.4 0.3 16.9 1.0 0.0 0.1 0.2 0.3 0.3 0.1 0.5 0.2 0.0 0.0 0.1 0.4 0.0 0.1 0.2 0.4 1.1 0.4 0.1 0.5 0.4 0.9 0.4 4.6 0.3 0.3 0.1 2.5 0.2 0.0 0.0 5.1 0.1 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 3.5 6.6 3.2 3.7 2.6 3.6 3.4 3.8 3.7 3.6 5.7 0.6 0.0 0.0 0.0 0.1 0.3 0.2 0.3 0.6 4.5 0.2 0.3 1.3 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 1.5 0.9 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.1 0.4 0.2 0.1 3.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 2.3 0.6 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.1 PCDHGB1 PCDH-GAMMA-B1 ENSG00000254221 "Protocadherin gamma subfamily B, 1" Q9Y5G3 5 141350102-141512979 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.5" "Cell type enhanced" "Detected in some" "Early spermatids: 5.7;Late spermatids: 7.6;Melanocytes: 1.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 12.9;ASC TERT1: 6.6;hTERT-RPE1: 7.1;T-47d: 8.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA076182" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Focal adhesion sites,Midbody" Yes No "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 34: Spermatids - Unknown function" "Vesicles, Plasma membrane" "Nucleoplasm, Focal adhesion sites, Midbody" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA076182: AB_2686783" "unprognostic (1.53e-2)" "unprognostic (1.94e-3)" "unprognostic (3.21e-1)" "unprognostic (4.38e-3)" "unprognostic (2.98e-1)" "unprognostic (8.36e-3)" "unprognostic (2.37e-1)" "unprognostic (9.57e-2)" "unprognostic (8.57e-2)" "unprognostic (1.06e-1)" "unprognostic (3.44e-2)" "unprognostic (4.78e-2)" "unprognostic (6.33e-2)" "unprognostic (3.15e-2)" "unprognostic (8.75e-2)" "unprognostic (1.93e-1)" "unprognostic (7.63e-3)" 0.6 0.7 1.8 0.1 1.2 0.0 0.5 2.1 1.6 0.6 0.0 0.3 0.0 1.2 0.4 0.3 0.4 0.5 0.5 2.9 1.6 0.4 0.1 0.6 0.0 1.9 3.3 1.4 0.8 2.3 1.0 0.2 2.4 0.6 0.1 1.6 0.3 0.9 0.2 0.2 0.1 0.9 2.4 0.1 0.1 0.4 1.8 0.0 0.6 0.3 0.0 0.3 0.3 3.5 0.1 1.9 1.6 0.0 12.9 6.6 0.1 1.2 3.2 0.5 0.7 0.2 0.5 0.5 4.2 0.5 3.1 0.6 0.3 0.2 0.4 0.0 0.8 0.0 0.2 1.2 0.2 0.0 0.0 1.0 0.0 0.0 0.0 7.1 0.1 0.0 0.2 0.2 3.0 1.7 0.4 0.3 0.2 0.0 0.0 0.0 2.4 0.1 0.0 0.0 1.0 0.7 0.0 0.8 0.1 1.2 8.6 0.0 1.0 0.2 1.3 1.1 0.0 0.0 2.4 0.3 2.5 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.2 2.1 1.6 2.9 1.6 1.9 3.3 2.4 2.4 1.8 3.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.7 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 1.8 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 PCDHGB2 PCDH-GAMMA-B2 ENSG00000253910 "Protocadherin gamma subfamily B, 2" Q9Y5G2 5 141360042-141512979 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 6.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 2.2;Cardiomyocytes: 1.4;Endometrial stromal cells: 1.0;Fibroblasts: 1.2" "Cancer enriched" "Detected in many" 5 "glioma: 6.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 13.5;ASC TERT1: 9.8;LHCN-M2: 8.2;REH: 7.8" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA077526" Uncertain Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane, Cytosol" Nucleoplasm "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA077526: AB_2732350" "unprognostic (7.14e-3)" "unprognostic (8.79e-3)" "unprognostic (3.21e-2)" "unprognostic (2.17e-1)" "prognostic unfavorable (8.67e-4)" "unprognostic (1.10e-2)" "unprognostic (2.19e-4)" "unprognostic (2.68e-1)" "unprognostic (2.64e-1)" "unprognostic (1.78e-1)" "unprognostic (1.05e-1)" "unprognostic (8.46e-3)" "unprognostic (4.59e-2)" "unprognostic (2.57e-1)" "unprognostic (3.06e-2)" "unprognostic (1.29e-1)" "unprognostic (3.36e-4)" 1.5 1.0 2.6 0.6 3.6 0.1 1.1 6.3 2.8 2.1 0.0 1.1 0.2 3.0 0.9 0.9 1.6 1.9 1.8 3.1 3.2 0.7 0.7 1.7 0.3 3.7 3.3 2.8 0.8 1.2 0.9 1.1 3.6 1.3 0.8 1.6 0.8 1.2 0.8 0.8 0.5 1.5 3.0 0.6 0.6 0.5 2.2 0.4 0.7 0.9 0.3 0.9 1.1 5.5 0.1 0.3 2.0 0.2 13.5 9.8 0.1 2.1 2.9 0.6 3.2 0.0 0.3 3.7 1.0 1.7 7.1 0.5 0.4 0.3 1.0 0.0 0.2 0.0 0.3 0.4 0.5 0.2 0.2 2.5 0.5 0.2 0.1 4.7 1.7 0.1 0.2 1.2 8.2 0.5 2.9 0.7 0.1 0.9 0.9 7.8 2.6 0.2 0.2 0.3 1.5 1.6 0.2 0.4 0.4 1.5 3.0 0.2 5.9 2.9 0.6 4.4 3.9 0.2 2.2 0.6 3.1 1.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 3.6 6.3 2.8 3.1 3.2 3.7 3.3 3.6 3.0 2.2 5.5 0.1 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.6 2.2 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 1.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.6 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 PCDHGB3 PCDH-GAMMA-B3 ENSG00000262209 "Protocadherin gamma subfamily B, 3" Q9Y5G1 5 141370242-141512975 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.8" "Cell type enhanced" "Detected in single" "Cardiomyocytes: 1.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 10.4;ASC TERT1: 8.4;fHDF/TERT166: 3.5;TIME: 5.5" "HPA008755, HPA010580, HPA035822, HPA035823" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 43: Cardiomyocytes - Nuclear processes" "Plasma membrane" "Nucleoplasm, Vesicles, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA035822: , HPA035823: AB_2674802" "unprognostic (6.93e-3)" "unprognostic (9.10e-4)" "unprognostic (1.35e-1)" "unprognostic (7.05e-2)" "unprognostic (1.51e-1)" "unprognostic (1.06e-1)" "unprognostic (1.24e-1)" "unprognostic (7.83e-2)" "unprognostic (1.92e-1)" "unprognostic (6.08e-2)" "unprognostic (2.04e-1)" "unprognostic (3.51e-2)" "unprognostic (5.81e-2)" "unprognostic (3.11e-1)" "unprognostic (3.62e-2)" "unprognostic (3.89e-2)" "unprognostic (2.80e-3)" 0.7 0.3 0.4 0.2 0.8 0.0 0.5 3.8 0.8 0.8 0.0 0.8 0.0 1.0 0.6 0.3 0.7 0.4 1.2 0.9 0.5 0.3 0.2 0.5 0.2 1.3 1.4 1.2 0.7 1.1 0.7 0.4 0.6 0.4 0.3 0.8 0.8 0.4 0.5 0.6 0.3 0.7 0.6 0.4 0.4 0.4 0.8 0.3 0.6 0.5 0.2 0.6 0.6 1.4 0.0 0.6 0.4 0.3 10.4 8.4 0.2 1.2 2.0 0.7 0.8 0.0 0.0 1.8 0.3 3.5 0.6 0.5 0.0 0.2 0.5 0.0 0.2 0.0 0.2 0.1 0.4 0.1 0.0 2.1 0.4 0.2 0.1 0.2 1.0 0.0 0.2 0.8 0.2 0.4 0.6 0.9 0.1 0.0 0.1 1.5 0.6 0.0 0.2 0.1 2.4 0.5 0.0 0.0 0.2 0.3 0.6 0.0 5.5 0.5 0.1 0.5 0.6 0.2 1.8 0.2 0.4 0.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 3.8 0.8 0.9 0.5 1.3 1.4 0.6 0.6 0.8 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PCDHGB4 "CDH20, FIB2, PCDH-GAMMA-B4" ENSG00000253953 "Protocadherin gamma subfamily B, 4" Q9UN71 5 141387698-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.1;Horizontal cells: 1.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 43.3;SuSa: 15.5;TIME: 22.7" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 56: Bipolar cells - Visual perception" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (3.33e-1)" "unprognostic (1.83e-3)" "unprognostic (2.91e-1)" "unprognostic (1.18e-1)" "unprognostic (1.23e-2)" "unprognostic (9.25e-3)" "unprognostic (2.20e-1)" "unprognostic (1.25e-2)" "unprognostic (1.99e-1)" "unprognostic (1.74e-1)" "unprognostic (1.29e-1)" "unprognostic (3.78e-2)" "unprognostic (2.31e-2)" "unprognostic (2.70e-2)" "unprognostic (2.62e-1)" "unprognostic (1.13e-1)" "unprognostic (3.27e-2)" 1.3 1.1 1.3 0.4 1.5 0.0 0.9 4.4 1.4 1.5 1.8 1.1 0.2 1.6 1.5 0.7 1.3 0.5 1.5 2.0 3.2 1.4 1.6 1.1 0.1 2.0 2.0 2.4 1.0 1.9 1.2 3.0 1.5 1.2 0.4 1.4 1.6 1.4 1.0 1.7 0.5 1.0 1.4 0.4 0.4 0.5 2.5 0.7 1.7 0.8 0.2 1.0 1.1 1.5 0.0 1.1 11.1 0.1 6.9 8.5 1.3 10.8 43.3 4.4 3.0 0.0 0.0 0.4 8.3 0.3 0.2 3.3 0.0 0.0 4.6 0.0 0.0 0.0 0.2 2.4 2.8 0.0 0.0 8.4 0.1 4.1 0.0 0.1 6.7 0.0 0.4 0.1 0.0 0.0 1.1 0.2 2.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.4 0.0 15.5 5.6 4.2 22.7 6.0 1.8 0.3 0.0 0.0 0.4 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.3 1.5 4.4 1.4 2.0 3.2 2.0 2.0 1.5 1.4 2.5 1.5 0.2 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.6 1.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 PCDHGB5 PCDH-GAMMA-B5 ENSG00000276547 "Protocadherin gamma subfamily B, 5" Q9Y5G0 5 141397987-141512979 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 20.3" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 1.2;Bipolar cells: 1.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 66.3;ASC TERT1: 49.6;BJ hTERT+ SV40 Large T+: 29.2;BJ hTERT+ SV40 Large T+ RasG12V: 32.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (2.71e-3)" "unprognostic (1.95e-2)" "unprognostic (1.09e-1)" "unprognostic (4.14e-2)" "unprognostic (2.35e-1)" "unprognostic (1.20e-1)" "unprognostic (3.64e-2)" "unprognostic (2.34e-2)" "unprognostic (1.54e-1)" "unprognostic (1.23e-1)" "unprognostic (1.90e-1)" "unprognostic (2.29e-1)" "unprognostic (1.69e-4)" "unprognostic (9.63e-3)" "unprognostic (3.21e-1)" "unprognostic (1.12e-1)" "unprognostic (8.25e-4)" 2.8 2.7 3.6 1.1 3.6 0.0 1.8 5.8 3.1 2.0 3.3 1.7 0.7 3.1 2.0 1.9 2.8 1.6 2.9 3.9 6.4 2.2 2.1 2.7 0.4 5.1 4.7 5.7 3.8 20.3 1.7 4.8 5.4 3.0 0.9 3.1 4.7 3.9 2.1 3.8 0.8 2.8 5.3 1.3 1.5 1.9 4.9 1.3 4.5 1.9 0.8 1.9 2.1 6.1 0.0 2.4 0.3 0.0 66.3 49.6 1.3 18.3 0.0 29.2 32.5 2.9 10.0 10.6 23.4 20.5 0.0 13.9 0.0 7.6 16.4 0.0 3.1 0.0 0.0 0.1 6.9 0.0 6.5 17.6 1.5 1.7 9.4 12.6 9.0 0.0 0.2 0.0 1.0 8.1 0.0 1.5 0.4 0.0 0.0 0.0 0.0 0.0 1.6 5.5 0.0 0.1 0.0 0.1 0.0 2.0 19.1 0.1 9.2 0.0 2.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 3.6 5.8 3.1 3.9 6.4 5.1 4.7 5.4 5.3 4.9 6.1 0.5 0.0 0.0 0.0 0.2 0.0 0.3 0.0 1.2 1.5 0.2 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.6 0.6 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.1 0.0 0.8 0.5 0.0 0.0 0.9 0.0 0.1 0.0 0.1 0.0 0.1 PCDHGB6 PCDH-GAMMA-B6 ENSG00000253305 "Protocadherin gamma subfamily B, 6" Q9Y5F9 5 141408021-141512979 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 6.9;Cone photoreceptor cells: 6.2;Horizontal cells: 10.1;Skeletal myocytes: 5.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 16.0;EFO-21: 5.4;HSkMC: 3.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (1.11e-1)" "unprognostic (4.18e-2)" "unprognostic (2.63e-1)" "unprognostic (7.81e-2)" "unprognostic (1.04e-1)" "unprognostic (1.90e-1)" "unprognostic (1.18e-1)" "unprognostic (1.85e-2)" "unprognostic (3.51e-1)" "unprognostic (1.11e-1)" "unprognostic (4.77e-2)" "unprognostic (9.89e-2)" "unprognostic (1.43e-1)" "unprognostic (2.17e-2)" "unprognostic (3.27e-1)" "unprognostic (1.21e-2)" "unprognostic (7.71e-4)" 3.1 3.1 3.0 0.9 3.6 0.4 2.2 5.0 2.4 2.9 2.9 2.4 0.5 3.2 2.0 1.2 2.9 1.7 2.4 2.5 3.5 1.1 1.3 2.0 0.7 3.6 3.5 6.0 1.2 2.8 1.8 3.1 3.2 1.4 0.7 2.8 2.2 2.4 2.9 2.1 1.0 1.9 3.3 1.5 1.1 0.6 3.7 0.6 2.6 1.5 0.6 1.8 2.3 3.9 0.0 0.1 16.0 0.1 0.5 0.6 0.8 1.4 0.0 0.4 0.9 0.2 0.2 1.4 5.4 0.9 0.2 0.3 0.0 0.3 1.0 0.0 0.3 0.0 0.2 0.1 1.3 0.1 0.1 3.6 1.8 0.8 0.1 0.1 0.5 0.3 0.1 0.2 0.1 0.3 0.1 1.1 0.6 0.0 0.0 0.2 0.0 0.1 2.5 0.2 0.2 0.3 0.0 0.1 0.1 0.4 1.2 0.3 2.6 0.1 0.2 0.2 0.1 0.0 0.1 0.0 0.2 0.0 0.7 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 3.0 3.6 5.0 2.4 2.5 3.5 3.6 3.5 3.2 3.3 3.7 3.9 3.6 3.2 0.5 0.0 1.0 0.0 1.5 0.0 0.0 6.9 0.6 0.4 3.9 0.0 1.3 0.0 6.2 0.2 0.6 0.4 0.0 0.7 0.0 0.6 3.8 2.6 0.0 0.0 0.0 1.2 0.1 3.3 1.1 0.5 0.0 0.4 1.4 0.7 0.3 10.1 0.0 0.4 0.0 0.0 0.0 0.2 1.8 0.2 0.0 0.0 0.1 2.7 0.0 0.0 0.0 2.0 0.1 1.2 1.5 0.8 0.1 0.3 0.7 2.5 0.0 5.2 3.2 0.2 0.5 0.3 0.1 0.1 0.7 0.8 0.4 0.8 PCDHGB7 "ME6, PCDH-GAMMA-B7" ENSG00000254122 "Protocadherin gamma subfamily B, 7" Q9Y5F8 5 141417645-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Bipolar cells: 7.9;Fibroblasts: 3.4;Horizontal cells: 3.3;Skeletal myocytes: 5.9" "Cancer enhanced" "Detected in many" "glioma: 7.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "AN3-CA: 86.7;HSkMC: 26.7;hTERT-RPE1: 72.4" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (1.22e-2)" "unprognostic (2.55e-2)" "unprognostic (7.39e-3)" "unprognostic (2.95e-1)" "unprognostic (1.49e-1)" "unprognostic (3.34e-1)" "unprognostic (1.98e-1)" "unprognostic (1.25e-1)" "unprognostic (8.40e-2)" "unprognostic (4.43e-2)" "unprognostic (2.61e-2)" "unprognostic (1.88e-2)" "unprognostic (3.05e-1)" "unprognostic (2.22e-2)" "unprognostic (1.44e-1)" "unprognostic (1.91e-1)" "unprognostic (5.68e-2)" 5.2 4.6 4.6 1.8 4.7 0.1 4.2 10.8 3.5 4.9 5.0 5.0 0.9 5.7 2.2 3.0 4.4 4.4 4.3 4.5 7.0 2.4 1.5 5.8 1.2 6.0 6.0 8.1 1.7 4.3 2.2 5.5 5.3 3.8 1.7 5.8 3.7 5.5 3.0 3.3 2.1 5.1 7.7 2.7 2.4 1.9 5.0 1.5 4.0 4.1 0.9 3.3 3.8 7.3 0.0 0.0 2.9 86.7 1.9 0.3 0.9 5.7 0.7 2.1 4.3 0.1 5.3 0.7 4.6 11.7 0.8 1.4 0.2 1.0 2.0 0.1 0.6 0.0 0.2 0.0 6.4 0.5 0.1 26.7 0.7 1.7 0.9 72.4 4.6 0.2 0.0 0.0 0.3 0.0 0.0 0.1 1.0 0.0 0.6 10.1 1.9 0.0 0.2 0.0 9.3 12.8 0.2 0.0 0.0 1.0 1.0 0.9 11.5 10.3 0.2 0.9 0.1 0.1 0.2 0.0 1.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.6 4.7 10.8 3.5 4.5 7.0 6.0 6.0 5.3 7.7 5.0 7.3 2.2 3.2 1.3 0.0 0.3 0.4 0.8 0.0 0.0 7.9 0.3 0.5 1.4 0.0 0.1 0.0 2.1 0.1 0.0 0.0 0.0 0.2 0.1 0.4 2.1 2.2 0.0 0.0 0.0 0.5 0.1 3.4 0.0 0.3 1.3 0.5 0.4 0.0 0.1 3.3 0.0 0.0 0.0 0.0 0.4 0.0 1.2 0.2 0.0 0.0 0.0 2.1 0.0 0.0 0.0 1.1 0.0 1.9 0.1 0.4 0.0 0.3 0.0 0.7 0.0 5.9 2.2 0.0 0.1 0.5 0.4 0.0 0.0 1.2 0.1 0.2 PCDHGC4 PCDH-GAMMA-C4 ENSG00000242419 "Protocadherin gamma subfamily C, 4" Q9Y5F7 5 141484997-141512979 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 31.4" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.1;Horizontal cells: 3.3" "Cancer enriched" "Detected in single" 10 "glioma: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "REH: 9.1;SCLC-21H: 7.3;SH-SY5Y: 14.2;SuSa: 10.0" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (6.05e-2)" "unprognostic (1.26e-3)" "unprognostic (4.78e-2)" "unprognostic (1.41e-1)" "unprognostic (3.44e-1)" "unprognostic (7.84e-2)" "unprognostic (9.48e-2)" "unprognostic (3.27e-1)" "unprognostic (4.55e-1)" "unprognostic (1.17e-1)" "unprognostic (8.72e-3)" "unprognostic (4.73e-3)" "unprognostic (2.20e-4)" "unprognostic (8.78e-2)" "unprognostic (3.06e-2)" "unprognostic (1.47e-1)" "unprognostic (2.75e-2)" 0.2 1.1 17.3 0.1 12.2 0.0 0.2 19.3 14.6 0.3 0.1 0.6 0.0 0.4 0.2 0.2 0.3 0.2 2.2 12.7 13.9 0.1 0.1 0.4 0.1 12.9 21.9 0.3 0.3 0.0 1.1 0.1 10.3 0.2 0.1 6.6 0.3 0.1 0.7 0.5 0.1 0.2 22.4 0.1 0.2 0.9 14.3 0.0 0.1 0.3 0.2 0.2 0.3 31.4 0.0 0.0 0.9 0.2 0.2 0.7 0.4 0.1 0.1 0.1 0.2 0.0 0.0 0.2 0.8 0.9 0.1 0.1 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.2 0.8 0.0 1.3 0.0 0.0 9.1 0.5 0.0 0.0 0.1 7.3 14.2 0.1 0.0 0.1 10.0 0.1 0.3 0.1 0.8 0.1 0.2 0.6 0.2 0.0 0.2 0.6 0.1 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.3 12.2 19.3 14.6 12.7 13.9 12.9 21.9 10.3 22.4 14.3 31.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 PCDHGC5 PCDH-GAMMA-C5 ENSG00000240764 "Protocadherin gamma subfamily C, 5" Q9Y5F6 5 141489081-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 28.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "glioma: 3.1;head and neck cancer: 0.8" "Region enhanced" "Detected in many" "hippocampal formation: 28.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 4.6;SuSa: 7.4;U-138 MG: 14.4;U-251 MG: 6.5;U-87 MG: 8.9" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA076140" Supported Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA076140: " "unprognostic (2.86e-3)" "unprognostic (7.63e-4)" "unprognostic (2.00e-1)" "unprognostic (3.52e-3)" "unprognostic (5.42e-2)" "unprognostic (1.14e-1)" "unprognostic (5.65e-2)" "unprognostic (2.38e-2)" "unprognostic (2.14e-1)" "unprognostic (3.16e-2)" "unprognostic (3.90e-1)" "unprognostic (1.66e-2)" "unprognostic (1.01e-9)" "unprognostic (6.87e-3)" "unprognostic (3.89e-2)" "unprognostic (3.13e-1)" "unprognostic (3.77e-3)" 0.3 0.5 5.6 0.1 8.6 0.0 0.3 0.0 11.7 0.8 0.0 1.3 0.0 1.2 0.2 0.3 0.7 0.2 5.3 28.4 0.0 0.2 0.1 0.7 0.0 0.0 0.0 0.7 0.4 0.0 1.2 0.1 0.0 0.5 0.0 1.2 0.4 0.5 1.2 0.5 0.2 0.7 0.0 0.1 0.3 0.6 0.3 0.1 0.2 0.2 0.0 0.5 0.6 0.0 0.0 0.0 0.3 0.3 0.3 1.5 0.1 0.8 0.5 0.4 0.5 0.0 0.0 0.4 1.4 2.2 0.1 0.1 0.0 0.4 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 3.2 0.0 4.6 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.8 0.8 0.2 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 7.4 0.1 0.2 0.1 14.4 0.2 0.2 6.5 0.0 0.0 0.0 8.9 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 8.6 0.0 11.7 28.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PES1 "NOP7, PES" ENSG00000100029 "Pescadillo ribosomal biogenesis factor 1" O00541 22 30576625-30607083 "Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040210, HPA062439, HPA066670" Supported Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes Yes "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA040210: AB_2676885, HPA062439: AB_2684764, HPA066670: AB_2685700" "unprognostic (1.82e-1)" "unprognostic (5.88e-2)" "unprognostic (5.59e-3)" "unprognostic (4.83e-2)" "unprognostic (1.48e-1)" "unprognostic (3.23e-3)" "prognostic unfavorable (1.84e-9)" "unprognostic (3.29e-2)" "unprognostic (3.40e-1)" "unprognostic (1.73e-1)" "unprognostic (4.79e-2)" "unprognostic (2.46e-2)" "unprognostic (5.65e-2)" "unprognostic (1.27e-3)" "unprognostic (1.65e-1)" "unprognostic (4.56e-2)" "unprognostic (1.42e-1)" 33.3 41.0 26.3 29.2 28.6 35.5 32.2 26.7 30.5 31.8 27.1 29.6 21.7 35.5 21.2 43.6 29.4 20.2 28.8 26.9 26.2 38.7 48.2 26.2 32.3 27.1 27.2 34.2 57.3 30.1 21.8 21.5 27.6 32.9 19.6 9.2 29.3 21.5 48.8 45.3 28.2 22.5 25.8 34.4 35.7 40.0 27.0 23.8 27.1 20.0 27.3 35.0 31.9 30.0 132.2 146.6 53.0 113.7 59.9 58.4 81.6 84.7 69.6 141.6 110.0 170.6 55.2 177.2 74.4 97.0 110.3 89.4 163.9 153.5 103.1 76.4 159.8 85.9 80.8 149.0 149.3 209.6 86.8 82.7 94.7 148.3 147.3 68.3 93.0 62.4 144.6 69.9 87.7 164.3 102.6 209.8 103.1 128.3 106.7 129.0 91.7 173.3 78.9 88.7 91.4 94.6 84.2 94.6 117.8 42.0 66.8 106.1 74.2 165.9 126.1 85.3 145.1 88.1 81.0 178.6 116.2 94.9 109.0 7.5 24.9 6.4 18.9 29.8 23.2 20.2 17.4 18.1 26.8 20.0 19.4 18.0 0.9 20.0 22.3 23.2 14.3 29.3 26.3 28.6 26.7 30.5 26.9 26.2 27.1 27.2 27.6 25.8 27.0 30.0 23.6 3.2 18.9 4.9 17.4 22.6 23.4 32.7 22.2 6.5 14.1 12.2 3.8 24.3 22.1 25.8 8.4 34.9 7.8 19.6 25.4 48.0 44.4 11.7 13.8 23.2 23.4 24.6 4.3 43.9 40.0 15.4 22.4 10.6 18.3 24.4 27.8 22.8 38.4 3.3 4.3 22.4 22.4 27.8 12.6 14.3 19.9 21.2 21.4 2.8 29.0 13.5 16.5 6.6 5.1 38.7 16.2 20.3 28.3 26.4 31.3 55.1 24.6 8.9 19.7 23.2 20.7 28.7 20.9 25.9 22.9 28.5 13.5 19.9 29.7 15.1 PHLPP2 "KIAA0931, PHLPPL, PPM3B" ENSG00000040199 "PH domain and leucine rich repeat protein phosphatase 2" Q6ZVD8 16 71637835-71724701 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 22.0;retina: 32.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 104.3;Distal enterocytes: 75.5;Excitatory neurons: 69.5;Proximal enterocytes: 73.7;Rod photoreceptor cells: 68.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040761, HPA041837, HPA048598" Approved Supported "Nucleoplasm,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 45: Intestine - Brush border" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 45: Enterocytes - Digestion" Cytosol "Nucleoplasm, Cytokinetic bridge, Mitotic spindle" "HPA040761: , HPA041837: , HPA048598: AB_2680459" "unprognostic (5.67e-2)" "unprognostic (2.00e-1)" "unprognostic (2.29e-2)" "unprognostic (2.44e-2)" "unprognostic (1.76e-1)" "unprognostic (1.59e-1)" "unprognostic (1.17e-1)" "unprognostic (3.27e-1)" "unprognostic (1.22e-1)" "unprognostic (3.43e-1)" "unprognostic (1.97e-4)" "unprognostic (3.08e-2)" "unprognostic (8.85e-3)" "unprognostic (6.41e-2)" "unprognostic (4.92e-2)" "unprognostic (8.46e-3)" "unprognostic (8.27e-2)" 4.2 2.8 6.6 2.8 7.5 6.5 2.7 5.8 7.4 3.5 0.1 11.7 11.1 3.7 2.9 1.4 3.2 2.4 2.8 7.8 4.8 3.4 3.0 3.1 3.5 4.6 3.9 4.2 3.1 4.5 4.0 2.7 4.7 2.7 12.2 32.2 1.7 3.4 1.9 1.8 22.0 4.5 0.6 2.5 2.4 6.8 5.3 1.9 6.6 2.6 3.2 3.3 2.4 5.1 6.0 7.8 8.3 9.3 6.5 7.8 4.8 8.8 8.0 12.5 10.1 7.2 1.9 11.8 3.4 14.6 9.0 12.4 12.1 4.5 16.1 4.2 6.5 3.3 7.3 4.8 5.1 2.9 5.0 5.8 2.5 17.7 5.7 5.2 4.7 4.1 3.0 3.2 8.7 12.7 3.9 2.3 6.5 1.9 2.1 6.3 7.3 3.9 5.9 4.5 7.2 3.8 18.9 5.1 3.1 6.4 6.3 1.6 6.5 12.5 9.0 5.3 7.4 7.1 5.4 11.9 7.7 2.3 2.8 0.2 0.1 0.0 0.2 0.1 0.2 0.5 0.1 0.3 0.1 0.3 0.2 0.2 0.2 0.7 0.1 0.5 0.3 0.1 6.6 7.5 5.8 7.4 7.8 4.8 4.6 3.9 4.7 0.6 5.3 5.1 4.0 9.6 2.2 26.1 7.4 9.3 5.1 3.5 7.4 20.6 6.9 5.6 3.3 0.0 3.6 3.7 104.3 4.3 3.8 75.5 0.0 2.7 12.0 2.9 6.1 5.3 6.0 22.9 69.5 2.3 0.4 7.7 1.1 5.1 10.2 11.3 2.9 4.1 1.5 23.5 45.9 6.7 4.1 7.0 12.7 6.3 5.3 2.7 14.2 10.3 3.2 6.5 1.0 30.7 32.7 2.5 31.4 5.3 4.0 8.2 73.7 5.1 3.1 68.6 6.6 7.8 7.9 31.6 20.4 1.9 9.1 1.4 4.9 1.7 9.2 2.2 PHPT1 "bA216L13.10, CGI-202, DKFZp564M173, HSPC141, PHP14" ENSG00000054148 "Phosphohistidine phosphatase 1" Q9NRX4 9 136848724-136851027 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 953.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013584, HPA020952" Approved Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA 590000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 28: BEWO - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "Nucleoplasm, Nuclear bodies, Plasma membrane" "CAB013584: , HPA020952: AB_1855331" "unprognostic (7.34e-2)" "unprognostic (9.21e-2)" "unprognostic (7.90e-2)" "unprognostic (1.57e-2)" "unprognostic (3.76e-2)" "unprognostic (2.30e-1)" "unprognostic (4.64e-2)" "unprognostic (1.69e-2)" "unprognostic (3.23e-2)" "unprognostic (1.82e-1)" "unprognostic (1.26e-3)" "unprognostic (5.85e-2)" "unprognostic (9.66e-3)" "unprognostic (1.11e-2)" "unprognostic (2.01e-1)" "unprognostic (3.95e-2)" "unprognostic (8.49e-2)" 71.5 109.2 196.7 54.5 200.5 64.6 62.4 206.2 245.6 76.0 192.2 74.0 54.0 44.7 103.0 70.6 99.3 62.0 267.2 192.3 203.3 82.6 47.9 57.3 57.4 199.3 191.9 65.0 153.4 160.9 85.2 49.8 200.3 89.2 50.5 26.3 144.0 86.6 432.6 45.8 62.9 78.1 198.8 41.6 61.5 56.9 199.1 68.5 86.7 441.5 40.0 71.8 41.4 216.2 53.6 452.5 225.6 199.1 153.4 266.0 412.8 147.6 170.8 158.8 138.6 165.7 138.0 145.1 142.8 168.6 180.0 155.0 51.2 293.9 50.2 116.9 132.5 45.4 276.8 380.3 177.5 82.6 176.4 322.8 248.7 91.8 109.5 145.8 218.8 93.1 102.9 129.7 257.2 328.2 156.9 176.7 216.0 372.5 206.6 106.5 106.6 196.7 255.6 113.3 137.6 132.8 146.7 155.8 75.1 107.0 127.2 226.4 177.0 390.6 130.8 91.5 166.5 60.5 93.4 94.0 174.3 59.7 235.8 38.2 290.0 31.0 197.6 318.4 170.7 241.3 173.9 184.6 321.8 178.9 126.0 175.8 13.7 196.7 231.7 425.4 223.6 324.1 196.7 200.5 206.2 245.6 192.3 203.3 199.3 191.9 200.3 198.8 199.1 216.2 125.7 96.1 159.8 24.8 111.8 150.3 187.7 659.2 204.9 43.9 223.1 317.7 384.8 178.7 326.5 217.0 22.9 322.1 111.8 337.1 747.4 196.1 271.3 122.2 168.1 111.9 265.1 80.2 8.1 252.4 489.5 213.1 140.6 170.3 123.5 367.4 83.6 201.9 286.5 67.3 12.5 370.9 309.3 97.2 197.1 953.5 205.0 133.6 334.4 5.6 273.2 194.7 146.2 10.6 25.0 185.3 359.8 223.4 187.8 257.5 540.1 817.4 250.6 77.7 85.5 137.1 249.6 141.8 143.8 140.3 161.8 264.1 106.4 352.5 336.0 199.5 PIK3CB PIK3C1 ENSG00000051382 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta" P42338 3 138652698-138834928 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Autophagy, Cell adhesion, Endocytosis" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 96.5;Inhibitory neurons: 92.4;Oligodendrocytes: 88.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEL: 115.2;HMC-1: 185.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031938, HPA042288, HPA064207" Approved Supported Nucleoplasm,Nucleoli,Vesicles,Midbody Yes No "Cluster 52: Eosinophils - Transcription" "Cluster 7: Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Nucleoli, Vesicles, Midbody" "CAB031938: AB_2165408, HPA042288: , HPA064207: AB_2685212" "unprognostic (4.89e-2)" "unprognostic (1.42e-2)" "unprognostic (5.97e-2)" "unprognostic (7.85e-2)" "unprognostic (4.89e-2)" "unprognostic (6.01e-2)" "prognostic unfavorable (6.42e-4)" "unprognostic (3.98e-2)" "unprognostic (1.35e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (3.99e-5)" "unprognostic (2.15e-1)" "unprognostic (6.18e-3)" "unprognostic (9.33e-2)" "unprognostic (7.82e-2)" "unprognostic (2.79e-1)" "unprognostic (4.59e-2)" 11.6 7.4 4.3 12.4 5.0 23.7 11.9 8.6 8.6 12.4 14.4 17.8 17.8 8.2 7.0 18.0 12.1 10.3 15.8 5.4 4.4 26.4 11.0 11.2 12.3 5.1 3.3 9.2 22.3 19.3 2.7 18.6 6.1 15.0 18.1 23.0 19.8 12.0 19.5 23.7 17.9 9.1 3.5 10.8 13.0 8.0 4.0 17.0 43.2 13.2 13.2 9.9 5.4 7.9 64.1 21.9 11.7 9.4 10.6 13.0 79.2 14.2 14.5 15.1 16.7 26.0 25.2 25.0 38.0 13.7 29.1 27.5 15.1 24.1 27.3 31.8 12.5 115.2 14.8 17.3 11.8 30.1 185.1 12.4 17.6 10.2 21.9 26.4 21.5 12.3 43.0 19.0 18.1 28.6 17.8 20.7 16.6 49.2 19.5 11.5 12.2 19.6 24.5 35.5 9.8 7.4 37.6 18.0 56.2 34.7 44.8 73.0 20.3 8.4 11.7 21.2 21.1 30.3 22.1 23.7 22.8 27.7 14.0 4.4 5.1 6.9 2.4 2.8 1.6 2.8 2.8 1.8 5.9 2.6 3.5 2.4 6.4 0.8 2.8 1.0 1.5 2.0 4.3 5.0 8.6 8.6 5.4 4.4 5.1 3.3 6.1 3.5 4.0 7.9 19.7 9.6 21.3 40.1 12.1 19.1 18.7 12.5 14.2 16.2 13.1 7.7 37.3 12.8 18.3 18.4 25.0 35.5 6.9 30.3 5.9 11.1 1.1 18.3 4.0 13.9 16.3 8.0 96.5 19.4 61.1 7.3 21.4 18.8 14.5 6.7 9.7 19.1 14.4 21.9 92.4 17.1 4.1 33.3 23.1 1.7 3.7 28.1 7.2 37.5 29.5 8.9 11.3 48.2 88.2 20.0 25.9 6.8 10.2 25.8 21.9 23.4 17.4 19.5 6.6 8.6 5.9 16.0 19.9 22.1 23.3 47.9 11.6 4.2 15.1 17.5 PIK3R6 "C17orf38, FLJ34500, HsT41028, p87PIKAP" ENSG00000276231 "Phosphoinositide-3-kinase regulatory subunit 6" Q5UE93 17 8802722-8867677 "Metabolic proteins, Predicted intracellular proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 2.9" "Cell type enhanced" "Detected in some" "Early spermatids: 11.5;granulocytes: 47.4;Hofbauer cells: 7.6;Late spermatids: 20.6;Microglial cells: 7.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "basophil: 21.9;eosinophil: 75.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 75.8" "Cell line enriched" "Detected in some" 8 "HMC-1: 148.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA023077 Approved Approved "Nucleoplasm,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Nucleoplasm, Golgi apparatus" "Plasma membrane, Cytosol" "HPA023077: AB_1854909" "unprognostic (4.29e-2)" "unprognostic (8.56e-3)" "unprognostic (9.39e-2)" "unprognostic (5.96e-3)" "unprognostic (2.46e-1)" "unprognostic (5.25e-3)" "unprognostic (4.50e-3)" "unprognostic (2.29e-2)" "unprognostic (3.12e-2)" "unprognostic (3.14e-1)" "unprognostic (2.20e-2)" "unprognostic (1.38e-1)" "prognostic unfavorable (1.50e-6)" "unprognostic (3.45e-1)" "unprognostic (3.91e-2)" "unprognostic (2.68e-1)" "unprognostic (8.98e-2)" 0.4 0.0 1.1 1.8 1.6 2.2 0.4 0.9 1.1 0.6 0.8 0.8 1.5 0.9 0.1 0.5 0.2 1.2 1.3 1.0 1.1 0.0 0.3 1.2 2.1 1.4 1.5 0.0 0.4 0.1 0.0 0.6 1.6 0.3 0.6 0.0 0.2 0.3 0.5 0.8 2.2 0.7 1.1 2.9 1.0 0.4 1.9 2.1 0.0 0.3 1.5 1.1 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 14.1 0.0 19.4 0.0 0.0 0.0 0.0 148.7 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.1 2.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.0 21.9 7.2 75.8 0.5 9.6 0.4 2.7 0.1 0.3 10.8 0.3 0.1 0.2 1.1 1.5 7.8 0.0 0.0 3.3 1.1 1.6 0.9 1.1 1.0 1.1 1.4 1.5 1.6 1.1 1.9 1.6 0.2 0.0 1.3 0.3 1.6 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.6 0.0 0.0 0.0 0.6 0.2 0.0 0.0 11.5 0.0 0.1 2.6 0.0 0.4 0.6 0.0 0.1 0.2 0.5 0.0 47.4 0.0 0.4 0.0 7.6 0.0 0.5 0.0 0.0 4.4 1.6 20.6 0.0 3.9 1.8 7.5 1.7 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.5 0.0 0.1 0.0 1.6 0.1 0.0 0.0 PKN2 "Pak-2, PRK2, PRKCL2, STK7" ENSG00000065243 "Protein kinase N2" Q16513 1 88684222-88836255 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell adhesion, Cell cycle, Cell division, Cilium biogenesis/degradation, Host-virus interaction, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 80.5" "Lineage enriched" "Detected in all" 8 "granulocytes: 80.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034861, HPA057913" Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Intermediate filaments,Centrosome,Cytosol" Yes No "Cluster 1: Neutrophils - Mixed function" "Cluster 34: Non-specific - Transcription" "Cluster 15: RT4 - Unknown function" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Intermediate filaments" "Nuclear bodies, Plasma membrane, Centrosome, Cytosol" "HPA034861: AB_2674363, HPA057913: AB_2732617" "unprognostic (7.52e-2)" "unprognostic (1.46e-1)" "prognostic favorable (5.67e-4)" "unprognostic (5.95e-2)" "unprognostic (3.39e-2)" "unprognostic (2.51e-2)" "unprognostic (4.64e-3)" "unprognostic (1.38e-1)" "unprognostic (4.43e-2)" "unprognostic (1.27e-2)" "unprognostic (2.90e-3)" "unprognostic (1.23e-1)" "unprognostic (1.51e-2)" "unprognostic (5.98e-2)" "unprognostic (2.38e-1)" "unprognostic (1.01e-2)" "unprognostic (1.99e-1)" 19.3 16.5 9.3 17.6 14.2 48.7 24.1 20.7 10.9 16.4 17.0 23.9 30.5 23.6 25.0 24.7 18.1 17.1 14.1 9.5 9.7 16.9 20.5 20.4 18.2 12.3 10.4 31.2 15.5 22.3 10.1 24.7 12.7 20.3 30.0 26.7 16.3 15.4 9.8 20.3 30.8 18.5 10.1 19.0 20.9 10.5 12.6 17.8 26.1 13.4 17.4 21.3 15.4 17.6 61.1 23.8 45.2 27.3 29.8 33.6 29.6 35.3 32.2 38.5 39.8 25.3 42.5 23.9 41.0 33.6 47.3 46.7 44.7 26.6 52.4 8.6 33.0 17.7 49.3 21.4 26.2 17.6 5.1 27.7 27.1 30.2 36.3 30.6 44.7 18.6 29.9 16.8 42.2 12.2 20.5 15.2 22.8 23.1 27.1 19.3 68.8 9.8 34.3 117.9 22.0 14.5 52.7 29.8 45.7 33.9 22.5 15.7 42.2 32.5 29.2 42.1 37.2 9.2 8.6 16.6 13.6 17.1 12.6 15.3 9.9 16.6 5.7 5.9 5.1 8.0 5.1 5.3 5.0 9.3 6.6 5.6 80.5 3.5 8.0 8.6 4.6 2.7 9.3 14.2 20.7 10.9 9.5 9.7 12.3 10.4 12.7 10.1 12.6 17.6 104.7 41.7 57.8 102.5 52.5 48.4 44.3 33.3 75.1 85.4 60.2 67.9 50.8 38.6 47.9 69.9 89.6 42.9 48.1 101.5 11.7 61.2 2.6 63.7 68.7 59.5 44.3 57.7 134.2 60.7 33.1 53.1 85.6 84.6 15.8 107.0 47.5 39.4 24.2 65.6 130.8 64.3 32.6 35.8 27.9 6.6 54.3 44.9 32.0 178.0 57.3 50.5 22.6 117.1 146.4 77.6 98.1 48.2 54.8 64.7 84.0 26.7 49.1 150.5 39.5 62.8 55.5 43.6 34.6 83.0 52.4 37.4 44.8 90.2 65.0 124.2 PLAG1 ZNF912 ENSG00000181690 "PLAG1 zinc finger" Q6DJT9 8 56160909-56211324 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Horizontal cells: 32.0;Microglial cells: 28.1;Rod photoreceptor cells: 27.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 16.0;ASC TERT1: 20.9;hTERT-HME1: 15.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA072290 Supported "Nucleoplasm,Nuclear speckles,Centrosome,Cytosol" NA NA "Cluster 30: Non-specific - Translation" "Cluster 77: Retina - Visual perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nuclear speckles" "Centrosome, Cytosol" "HPA072290: AB_2686508" "unprognostic (1.89e-2)" "unprognostic (1.93e-2)" "unprognostic (1.22e-3)" "unprognostic (1.63e-4)" "unprognostic (6.81e-2)" "unprognostic (1.07e-1)" "unprognostic (5.63e-3)" "unprognostic (8.56e-2)" "unprognostic (1.18e-1)" "unprognostic (7.99e-2)" "unprognostic (3.42e-2)" "unprognostic (1.97e-1)" "unprognostic (1.32e-3)" "unprognostic (2.83e-2)" "unprognostic (3.94e-1)" "unprognostic (1.21e-2)" "unprognostic (6.14e-2)" 0.7 1.4 0.8 1.0 1.2 0.9 0.9 2.5 1.1 3.0 0.6 0.8 1.4 1.4 4.1 0.7 3.1 0.7 3.1 0.7 1.0 1.3 0.3 1.9 1.8 1.5 1.4 4.9 0.8 1.2 3.8 1.6 1.8 1.3 0.6 7.7 3.0 1.8 0.4 1.4 2.3 0.4 1.2 2.6 1.3 2.4 1.3 2.8 1.3 1.4 2.3 1.3 3.0 2.0 2.0 0.0 11.9 0.1 16.0 20.9 3.7 5.4 6.9 2.5 1.1 0.8 6.2 0.2 5.1 2.9 0.7 0.4 3.4 7.1 2.5 0.2 7.4 8.0 0.8 1.8 3.3 2.5 2.3 14.9 3.9 1.4 15.6 6.9 4.7 5.3 3.4 0.1 5.3 0.1 0.7 4.7 3.4 0.5 1.8 6.1 0.8 4.9 3.2 0.7 0.1 0.0 0.1 0.1 0.4 8.0 0.1 2.4 7.2 3.6 4.6 5.9 1.4 1.8 1.5 2.9 4.1 0.9 1.0 0.6 0.0 0.4 0.1 0.0 0.1 1.3 0.4 0.2 0.0 0.7 1.8 1.8 0.4 0.3 0.2 0.1 0.1 0.4 0.8 1.2 2.5 1.1 0.7 1.0 1.5 1.4 1.8 1.2 1.3 2.0 2.6 6.4 3.2 2.9 13.0 1.0 2.5 6.2 1.8 23.6 1.6 0.6 12.2 4.3 6.7 5.5 25.0 8.3 2.0 1.0 0.0 0.7 6.2 3.0 2.3 3.7 5.4 5.0 16.8 1.3 4.2 4.0 2.6 4.2 1.3 0.4 15.7 0.7 5.8 32.0 12.3 3.6 6.1 2.9 2.2 6.7 15.2 2.8 16.0 28.1 1.2 16.3 4.1 2.0 19.2 1.4 4.1 10.1 6.3 5.0 5.1 0.8 9.1 27.8 0.0 2.4 1.4 9.0 8.8 1.1 0.9 7.1 4.5 0.9 3.6 12.9 PLEKHG3 "ARHGEF43, KIAA0599" ENSG00000126822 "Pleckstrin homology and RhoGEF domain containing G3" A1L390 14 64704102-64750249 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 179.2" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 90.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "granulocytes: 24.0;NK-cells: 9.4;T-cells: 16.2" "Cell line enhanced" "Detected in many" "A-431: 78.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063455, HPA065323, HPA073702, HPA074734" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge,Centrosome,Cytosol" Yes No "Cluster 5: Granulocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "Nucleoplasm, Cytokinetic bridge, Centrosome" "HPA063455: AB_2685015, HPA065323: AB_2685467, HPA073702: AB_2732238, HPA074734: AB_2732265" "unprognostic (8.71e-2)" "unprognostic (1.69e-1)" "unprognostic (4.38e-2)" "unprognostic (4.04e-2)" "unprognostic (2.18e-1)" "unprognostic (7.22e-2)" "unprognostic (7.21e-2)" "unprognostic (5.53e-3)" "unprognostic (1.49e-1)" "unprognostic (3.34e-3)" "unprognostic (3.63e-1)" "unprognostic (3.54e-2)" "prognostic favorable (7.39e-8)" "unprognostic (2.29e-1)" "unprognostic (2.67e-1)" "unprognostic (4.24e-2)" "unprognostic (2.67e-3)" 25.2 3.5 44.0 10.7 92.5 16.3 23.4 47.2 74.1 33.9 53.0 39.0 13.0 67.5 5.0 45.8 38.1 22.6 17.2 44.5 46.7 36.0 36.3 14.3 5.6 65.8 66.3 33.8 33.0 17.0 6.8 29.3 60.9 24.2 15.5 2.9 29.2 37.5 9.7 44.9 13.2 26.4 37.9 26.6 22.3 5.7 74.1 4.6 23.7 7.4 4.9 32.2 39.1 179.2 78.4 36.5 29.8 45.3 3.1 0.0 49.0 8.7 10.4 13.8 11.0 38.9 34.3 0.0 15.3 8.6 4.8 74.6 20.3 69.7 4.7 0.2 16.7 35.1 48.3 9.2 4.0 1.3 16.1 3.9 39.6 2.9 24.4 22.9 9.1 0.3 0.0 0.4 4.6 37.5 0.1 32.0 10.0 21.2 37.0 0.4 14.7 5.5 37.0 58.0 9.9 18.0 17.7 26.7 25.1 27.5 29.0 8.0 16.6 6.0 59.8 0.3 12.3 0.1 0.2 0.1 0.6 3.7 10.7 9.0 3.0 18.2 16.2 1.5 11.1 0.0 5.0 7.3 1.0 0.0 0.5 3.6 24.0 9.4 1.0 0.0 1.7 5.3 44.0 92.5 47.2 74.1 44.5 46.7 65.8 66.3 60.9 37.9 74.1 179.2 3.1 3.2 6.2 15.0 0.7 19.4 19.4 15.1 21.6 5.5 16.0 9.8 7.8 12.8 6.0 47.8 0.0 7.9 14.5 24.7 11.7 26.7 0.9 18.6 18.5 4.0 34.7 0.4 1.0 20.6 9.5 7.4 14.3 23.6 1.3 1.9 3.6 10.1 5.5 0.0 3.2 26.9 18.3 6.5 8.0 1.5 7.5 2.7 5.4 6.5 4.6 9.1 45.3 10.6 90.9 35.3 16.7 25.6 2.8 16.1 2.3 9.5 4.0 0.8 26.3 5.1 25.3 0.2 1.6 25.6 21.5 2.6 9.0 10.5 13.2 32.2 PLEKHH2 "KIAA2028, PLEKHH1L" ENSG00000152527 "Pleckstrin homology, MyTH4 and FERM domain containing H2" Q8IVE3 2 43637260-43767987 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Collecting duct cells: 66.2;Endometrial stromal cells: 150.5;Oligodendrocyte precursor cells: 191.0" "Cancer enhanced" "Detected in many" "renal cancer: 6.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 7.4;RPTEC TERT1: 6.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077225 Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 36: Stromal cells - Cell proliferation" "Plasma membrane, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA077225: AB_2686828" "unprognostic (1.11e-1)" "unprognostic (1.05e-1)" "unprognostic (3.49e-2)" "unprognostic (1.59e-1)" "unprognostic (2.16e-1)" "unprognostic (4.27e-3)" "unprognostic (1.77e-1)" "unprognostic (2.32e-2)" "unprognostic (2.94e-2)" "unprognostic (6.99e-2)" "unprognostic (2.81e-1)" "unprognostic (2.53e-2)" "unprognostic (1.92e-3)" "unprognostic (3.03e-2)" "unprognostic (1.29e-1)" "unprognostic (8.57e-3)" "unprognostic (1.82e-2)" 13.1 3.0 2.8 1.7 2.7 0.1 8.9 3.6 2.8 20.9 8.8 11.8 3.7 19.8 4.4 4.6 15.9 7.3 4.8 2.3 2.8 15.9 1.7 27.6 2.9 3.0 3.4 23.0 2.9 5.4 2.0 3.8 3.1 5.1 4.3 1.7 4.8 5.0 1.8 8.4 6.5 9.8 2.7 5.4 5.0 3.9 2.7 0.4 5.5 2.5 1.8 6.2 8.5 2.5 0.5 4.0 1.6 0.0 3.1 7.4 0.3 0.5 2.0 0.8 2.0 0.0 1.3 1.0 0.2 0.6 3.3 2.6 0.5 0.6 1.5 0.0 1.1 0.1 0.6 0.1 0.5 0.0 0.5 2.2 0.6 1.9 0.1 1.1 1.7 1.6 3.9 0.1 0.7 1.1 0.8 0.1 0.9 0.6 3.9 0.0 4.6 0.0 6.3 0.2 1.2 0.6 0.4 0.0 3.9 1.1 0.5 0.1 0.2 4.5 1.3 0.2 1.4 0.9 0.2 0.0 1.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.8 2.7 3.6 2.8 2.3 2.8 3.0 3.4 3.1 2.7 2.7 2.5 4.6 38.5 8.7 19.2 0.9 8.7 17.5 5.8 6.8 1.0 5.3 8.3 2.9 11.5 12.9 66.2 6.2 0.3 1.3 0.1 5.9 6.2 1.6 5.9 150.5 3.8 0.0 0.0 15.6 1.4 0.3 57.4 3.1 8.8 1.3 42.6 2.2 0.0 0.8 0.0 4.3 0.3 2.0 0.3 8.6 3.3 35.8 1.2 12.4 15.9 0.2 5.8 0.0 191.0 52.7 7.2 0.0 50.4 0.4 9.2 0.3 4.1 7.3 4.1 46.0 40.7 24.6 10.8 5.9 2.6 8.4 0.5 3.6 13.1 0.6 8.7 POU2F3 "Epoc-1, OCT11, PLA-1, Skn-1a" ENSG00000137709 "POU class 2 homeobox 3" Q9UKI9 11 120236640-120319945 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 48.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 20.9;Pancreatic endocrine cells: 20.8;Suprabasal keratinocytes: 37.6;Urothelial cells: 14.2" "Cancer enhanced" "Detected in many" "ovarian cancer: 3.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 1.4;CAPAN-2: 3.6;EFO-21: 1.3;SK-BR-3: 2.5;T-47d: 3.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA019652, HPA073468" Enhanced Approved "Nucleoplasm,Nucleoli,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 61: Skin - Cornification" "Cluster 6: T47d - Mammary gland" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm "Nucleoli, Nuclear bodies, Plasma membrane, Cytosol" "HPA019652: AB_1855585, HPA073468: " "unprognostic (1.75e-1)" "unprognostic (2.12e-2)" "unprognostic (6.37e-2)" "unprognostic (2.41e-4)" "unprognostic (2.60e-1)" "unprognostic (4.46e-3)" "unprognostic (8.56e-3)" "unprognostic (9.34e-2)" "unprognostic (3.45e-2)" "unprognostic (1.12e-1)" "unprognostic (1.40e-3)" "unprognostic (2.08e-1)" "unprognostic (1.27e-2)" "unprognostic (9.69e-3)" "unprognostic (1.70e-1)" "prognostic favorable (8.14e-4)" "unprognostic (1.45e-1)" 0.1 0.1 0.2 0.1 0.1 0.2 2.0 0.3 0.4 0.8 0.0 0.6 0.9 0.0 1.7 1.3 0.5 0.7 0.1 0.1 0.1 0.3 0.1 1.0 0.2 0.1 0.1 0.1 0.2 6.3 0.4 0.3 0.1 0.6 0.2 0.1 1.1 2.0 0.2 48.0 0.7 0.3 0.0 0.2 0.7 0.1 0.1 0.2 0.7 0.0 0.5 0.4 2.1 0.3 1.4 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.3 0.0 0.0 0.0 3.6 0.1 1.3 0.0 0.0 0.6 0.0 0.2 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 0.0 0.0 1.1 0.2 0.0 0.0 2.5 0.0 0.3 3.9 0.1 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.4 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.3 0.2 0.0 8.2 0.3 0.0 20.9 10.6 5.0 1.8 0.0 3.0 1.5 0.8 0.0 3.9 11.0 0.0 1.5 0.1 0.9 0.0 5.3 2.2 1.3 0.7 0.3 3.0 0.0 0.4 1.3 0.4 0.6 10.2 4.8 0.0 0.0 0.0 0.3 0.1 0.0 0.5 0.2 8.2 0.0 2.2 5.5 0.0 0.1 5.4 0.0 0.0 0.4 0.0 0.0 0.5 20.8 1.1 0.0 0.0 5.0 0.4 0.1 1.8 0.0 0.0 0.0 0.4 0.0 0.1 7.0 37.6 7.9 0.5 0.2 0.6 14.2 PPID CYP-40 ENSG00000171497 "Peptidylprolyl isomerase D" Q08752 4 158709127-158723396 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Protein transport, Transport" "Chaperone, Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019520, HPA019692" Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA NA 480000 "Cluster 2: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 10: Non-specific - Unknown function" Cytosol "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA019520: AB_1847400, HPA019692: AB_1847401" "unprognostic (4.26e-2)" "unprognostic (2.03e-2)" "unprognostic (8.91e-3)" "unprognostic (8.17e-3)" "unprognostic (1.50e-1)" "unprognostic (2.04e-3)" "unprognostic (4.72e-2)" "unprognostic (1.62e-2)" "unprognostic (4.72e-2)" "unprognostic (5.92e-2)" "unprognostic (4.54e-2)" "unprognostic (1.46e-2)" "unprognostic (2.66e-3)" "unprognostic (8.78e-2)" "unprognostic (1.74e-1)" "unprognostic (1.64e-1)" "unprognostic (1.09e-1)" 26.8 38.3 38.0 24.4 40.2 25.1 22.8 40.4 77.6 25.4 46.4 33.9 50.6 24.2 19.0 27.7 24.1 18.8 49.6 40.1 44.2 39.5 87.6 19.8 28.6 39.0 39.4 24.2 31.7 17.0 28.6 21.6 40.2 23.5 20.3 36.2 23.3 18.7 88.9 36.1 45.3 18.9 39.6 29.1 29.0 24.1 42.2 24.3 23.9 45.5 25.8 27.4 24.0 46.9 46.7 42.3 41.8 57.7 60.7 45.2 63.1 44.9 24.3 40.3 30.4 55.4 30.9 48.9 19.7 42.0 63.4 35.1 127.9 51.5 48.8 162.9 44.4 87.5 36.5 76.9 46.8 55.6 63.0 28.9 41.2 34.6 51.5 52.0 44.6 81.9 111.0 84.4 45.5 44.6 80.0 49.9 57.9 75.5 55.8 35.9 20.7 41.7 44.6 23.0 70.2 47.1 33.8 69.2 65.6 60.0 31.9 52.2 43.7 40.1 45.3 44.7 60.2 48.3 107.2 62.0 51.1 59.4 41.1 68.8 23.9 55.2 31.1 35.4 36.0 22.3 30.2 29.1 26.4 25.4 30.9 32.0 32.9 40.5 37.7 26.9 37.0 28.0 38.0 40.2 40.4 77.6 40.1 44.2 39.0 39.4 40.2 39.6 42.2 46.9 29.2 6.4 13.4 13.1 24.8 10.1 29.7 17.5 9.1 30.2 19.1 20.8 59.7 25.8 27.9 27.6 22.9 41.5 38.7 17.1 37.2 39.2 39.0 66.1 39.9 25.1 19.6 17.4 24.3 23.0 49.5 24.3 14.3 28.5 32.3 24.4 17.2 18.5 41.9 75.7 28.6 28.3 22.4 17.0 14.7 23.1 20.5 26.0 14.2 9.4 51.6 23.3 48.4 15.1 28.3 29.5 27.4 22.6 22.3 31.6 39.7 33.7 62.3 32.3 6.6 17.7 58.2 96.0 77.5 16.9 11.8 47.6 33.7 33.7 32.0 20.2 PRC1 ASE1 ENSG00000198901 "Protein regulator of cytokinesis 1" O43663 15 90966040-90995629 "Predicted intracellular proteins" "Cell cycle, Cell division" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 89.9;testis: 55.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 142.9;Extravillous trophoblasts: 68.3;Spermatocytes: 136.4;Spermatogonia: 74.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 34.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 34.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034521, HPA048816" Enhanced Supported "Nucleoplasm,Plasma membrane,Microtubules,Cytokinetic bridge,Midbody" Yes Yes "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Microtubules, Cytokinetic bridge, Midbody" Nucleoplasm "HPA034521: AB_10670169, HPA048816: " "unprognostic (1.14e-1)" "unprognostic (3.98e-2)" "unprognostic (9.21e-2)" "unprognostic (1.75e-3)" "unprognostic (2.39e-1)" "unprognostic (3.43e-2)" "prognostic unfavorable (2.11e-4)" "unprognostic (1.24e-3)" "unprognostic (3.86e-3)" "unprognostic (1.65e-2)" "prognostic unfavorable (2.76e-5)" "unprognostic (2.49e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.09e-2)" "unprognostic (1.79e-1)" "unprognostic (7.90e-2)" "unprognostic (3.92e-2)" 7.4 6.2 6.4 10.0 6.1 89.9 6.4 10.3 8.4 8.1 5.0 16.3 10.6 5.7 2.3 37.6 6.0 3.0 6.9 5.6 4.9 5.6 4.8 9.0 16.9 4.8 5.2 8.1 8.9 2.6 3.6 15.3 5.2 4.9 16.5 4.9 9.5 1.5 4.1 20.1 13.0 9.4 4.9 12.5 11.7 55.0 4.2 43.0 4.3 2.3 24.9 4.8 13.7 5.6 167.9 199.9 164.8 113.6 16.8 28.7 87.5 237.8 139.3 257.2 195.3 134.6 158.5 65.5 91.4 151.9 156.9 220.9 188.8 101.2 240.6 118.7 206.4 135.6 263.5 123.5 4.1 71.4 109.0 7.7 12.8 145.8 146.9 56.6 146.4 100.5 114.0 132.4 241.1 144.4 66.9 98.5 66.6 216.4 84.9 69.7 205.1 86.3 115.3 123.6 151.2 118.9 225.4 121.9 82.7 112.3 149.1 127.1 91.2 168.2 146.0 140.5 345.1 43.5 127.7 80.0 74.5 162.0 265.3 34.4 0.6 2.9 0.6 0.1 0.4 1.1 1.3 1.3 2.4 0.5 1.2 0.4 0.4 3.0 0.3 2.6 8.0 1.0 6.4 6.1 10.3 8.4 5.6 4.9 4.8 5.2 5.2 4.9 4.2 5.6 2.5 0.0 3.1 1.3 6.8 16.6 6.6 8.0 2.2 6.4 3.4 4.3 3.2 0.0 7.6 3.7 0.0 45.5 2.8 16.5 0.0 3.2 41.5 4.5 4.0 4.7 5.4 142.9 5.0 2.9 68.3 7.2 16.3 6.8 8.9 13.2 9.3 2.1 21.5 3.3 5.2 17.0 10.2 8.7 15.0 15.4 3.7 5.2 3.6 1.9 5.5 3.8 4.1 2.0 1.7 2.3 3.2 1.9 17.5 5.9 2.0 0.1 3.2 4.6 6.6 7.4 10.9 136.4 74.2 38.0 14.2 14.6 6.8 0.4 24.1 6.7 PRPF40B HYPC ENSG00000110844 "Pre-mRNA processing factor 40 homolog B" Q6NWY9 12 49568218-49644666 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Spermatocytes: 61.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038426, HPA038599" Enhanced Approved "Nucleoplasm,Nuclear bodies,Aggresome,Cytosol" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nuclear bodies" "Nucleoplasm, Aggresome, Cytosol" "HPA038426: AB_10674684, HPA038599: AB_10674689" "unprognostic (1.03e-1)" "unprognostic (2.32e-2)" "unprognostic (2.44e-3)" "unprognostic (2.36e-2)" "unprognostic (1.83e-1)" "unprognostic (2.47e-1)" "unprognostic (7.50e-6)" "unprognostic (1.02e-1)" "unprognostic (1.56e-1)" "unprognostic (1.45e-1)" "unprognostic (5.06e-3)" "unprognostic (3.31e-1)" "unprognostic (3.29e-3)" "unprognostic (3.23e-2)" "unprognostic (2.05e-1)" "unprognostic (3.01e-1)" "unprognostic (2.80e-2)" 8.3 16.3 16.3 3.2 15.6 0.7 11.5 13.3 18.8 23.9 13.7 15.6 4.0 17.9 10.4 10.4 19.1 6.4 15.6 16.6 16.5 23.9 9.2 7.4 3.1 16.4 14.5 25.4 16.0 20.3 26.2 6.5 15.9 17.5 3.4 12.3 13.3 11.7 25.2 11.4 7.6 7.8 13.3 9.5 14.5 33.7 14.7 3.5 29.2 13.5 3.4 14.6 14.6 15.3 7.2 10.5 10.3 10.0 8.4 5.4 9.5 5.8 8.1 6.1 3.0 12.2 15.8 5.8 12.0 7.7 8.6 4.2 6.3 20.1 3.1 4.4 2.5 6.1 4.2 4.4 10.6 2.0 7.8 7.7 16.8 6.1 22.0 13.2 4.9 11.7 3.0 3.0 7.3 6.7 1.4 4.2 4.4 8.2 3.9 5.1 1.6 4.8 13.0 6.6 10.9 13.1 4.7 12.8 7.2 9.4 24.5 5.7 2.0 3.7 14.9 4.9 2.5 7.1 4.3 2.4 11.2 1.5 3.5 0.0 0.1 0.0 0.8 0.1 1.1 0.3 0.8 0.3 0.2 0.6 0.8 0.9 0.0 1.3 0.0 0.5 0.3 0.3 16.3 15.6 13.3 18.8 16.6 16.5 16.4 14.5 15.9 13.3 14.7 15.3 5.3 12.8 20.3 15.7 4.1 3.6 8.7 10.2 11.4 19.1 6.6 9.7 1.2 5.7 17.5 18.4 10.4 21.9 1.2 1.5 7.9 13.8 28.9 8.6 7.5 5.2 7.7 3.0 19.3 11.1 7.4 7.2 4.1 5.6 2.5 15.6 8.2 3.1 5.4 11.8 22.9 3.2 12.2 1.6 2.1 23.1 11.8 1.5 3.6 6.5 4.9 8.3 2.1 20.6 17.2 6.8 1.1 12.0 1.1 6.7 1.4 5.6 24.5 19.8 13.1 9.8 9.7 61.3 26.6 8.0 6.0 26.4 3.1 9.2 5.2 5.0 PRR19 MGC70924 ENSG00000188368 "Proline rich 19" A6NJB7 19 42302098-42310814 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 21.6" "Group enriched" "Detected in some" 9 "Early spermatids: 26.7;Late spermatids: 60.1;Spermatocytes: 37.9;Spermatogonia: 22.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA070350 Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Nuclear bodies,Mitotic chromosome,Mitochondria" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nucleoli, Nucleoli rim, Mitotic chromosome" "Nucleoplasm, Nuclear bodies, Mitochondria" "HPA070350: AB_2686259" "unprognostic (2.05e-1)" "unprognostic (8.03e-3)" "unprognostic (4.02e-2)" "unprognostic (7.55e-3)" "unprognostic (7.33e-2)" "unprognostic (1.08e-2)" "unprognostic (2.44e-5)" "unprognostic (3.57e-1)" "unprognostic (1.92e-2)" "unprognostic (8.10e-3)" "unprognostic (3.85e-2)" "unprognostic (2.77e-1)" "unprognostic (2.87e-3)" "unprognostic (4.21e-1)" "unprognostic (7.26e-2)" "unprognostic (1.78e-1)" "unprognostic (4.36e-2)" 0.4 1.1 1.9 0.7 2.5 2.3 0.5 2.1 2.4 0.7 1.3 0.4 0.4 0.6 0.4 1.1 0.5 0.5 0.2 1.9 1.7 0.7 0.6 0.3 0.5 1.8 1.5 0.5 0.4 0.4 0.9 0.4 1.9 0.7 0.2 0.5 0.7 0.4 0.3 0.7 0.5 0.3 1.4 0.5 0.4 21.6 2.0 0.6 0.4 0.1 0.5 0.4 0.7 2.0 2.7 3.9 2.2 2.9 0.1 0.2 2.2 1.2 1.2 3.5 3.5 1.6 2.5 0.5 4.5 1.3 2.6 0.8 1.0 1.0 0.7 1.8 1.0 2.8 2.0 1.0 0.8 0.7 1.6 1.1 1.6 2.3 0.4 0.7 0.6 2.9 1.5 1.3 1.6 6.2 2.7 1.3 2.3 2.5 0.0 1.0 0.4 0.2 1.1 2.1 4.9 1.9 2.1 1.5 0.6 0.6 2.0 1.0 0.8 2.3 3.4 0.5 2.1 0.2 1.0 0.8 2.4 2.0 2.4 0.4 0.4 0.1 0.4 0.4 0.1 0.6 0.3 0.5 0.5 0.4 0.4 0.2 0.4 0.5 0.1 0.3 0.5 0.2 1.9 2.5 2.1 2.4 1.9 1.7 1.8 1.5 1.9 1.4 2.0 2.0 1.2 0.0 0.5 0.0 0.7 0.6 0.9 1.9 4.0 0.4 2.7 2.8 0.5 0.0 0.6 0.0 0.0 0.9 0.3 0.8 1.9 0.9 26.7 1.0 0.7 1.2 0.0 0.0 0.4 1.2 0.6 0.6 1.1 1.5 0.0 0.3 0.0 0.4 0.8 1.7 0.4 0.1 0.0 0.0 0.3 60.1 1.2 0.4 0.0 1.0 0.1 0.0 1.0 1.0 0.3 0.4 1.2 1.2 0.6 0.4 0.6 0.6 2.3 0.2 0.0 0.8 0.7 37.9 22.5 2.1 0.9 0.5 0.4 0.6 0.4 0.7 PRR23A ENSG00000206260 "Proline rich 23A" A6NEV1 3 139003962-139006268 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "testis: 1.5" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 17 "testis cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047473 Uncertain Approved "Nucleoplasm,Nuclear bodies,Microtubules,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 78: Testis - Spermatogenesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Microtubules" "Nuclear bodies, Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA047473: AB_2680062" "unprognostic (1.48e-1)" 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.6 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.2 0.1 0.0 0.2 0.1 0.2 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRR23B FLJ46116 ENSG00000184814 "Proline rich 23B" Q6ZRT6 3 139019031-139020926 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 13 "testis: 1.3" "Group enriched" "Detected in some" 8 "Spermatocytes: 6.4;Spermatogonia: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047473 Uncertain Uncertain "Nucleoplasm,Nuclear bodies,Microtubules,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 83: Testis - Spermatogenesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Microtubules" "Nuclear bodies, Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA047473: AB_2680062" "unprognostic (7.57e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.4 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 PRR23C FLJ46210 ENSG00000233701 "Proline rich 23C" Q6ZRP0 3 139042102-139044892 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Early spermatids: 3.5;Late spermatids: 2.0;Spermatocytes: 1.6;Spermatogonia: 3.5" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.2" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.2" "Not detected" "Not detected" HPA047473 Uncertain Approved "Nucleoplasm,Nuclear bodies,Microtubules,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 17: Basophils - Unknown function" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nucleoplasm, Microtubules" "Nuclear bodies, Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA047473: AB_2680062" "unprognostic (1.00e-1)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.3 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 3.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 PRUNE2 "A214N16.3, bA214N16.3, BMCC1, BNIPXL, C9orf65, KIAA0367" ENSG00000106772 "Prune homolog 2 with BCH domain" Q8WUY3 9 76611376-76906114 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 120.6;intestine: 110.9" "Cell type enriched" "Detected in many" 6 "Oligodendrocytes: 918.7" "Cancer enhanced" "Detected in many" "renal cancer: 15.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 51.1;LHCN-M2: 83.2;RH-30: 71.5;RPTEC TERT1: 40.1" "Low region specificity" "Detected in all" "HPA022470, HPA031079" Uncertain Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus, Cytosol" "Nucleoplasm, Nucleoli" "HPA022470: AB_1845832, HPA031079: AB_10603230" "unprognostic (1.21e-1)" "unprognostic (3.65e-2)" "unprognostic (6.06e-2)" "unprognostic (2.13e-2)" "unprognostic (3.23e-1)" "unprognostic (2.43e-3)" "unprognostic (8.56e-2)" "unprognostic (1.15e-2)" "unprognostic (3.60e-1)" "unprognostic (8.69e-2)" "unprognostic (2.11e-2)" "unprognostic (9.79e-2)" "prognostic favorable (1.37e-6)" "unprognostic (7.75e-2)" "unprognostic (1.06e-1)" "unprognostic (3.25e-3)" "unprognostic (3.80e-4)" 11.3 23.2 26.9 11.9 82.9 2.9 5.2 49.5 54.7 16.6 0.0 110.9 7.1 50.6 18.5 34.0 29.4 16.4 8.9 26.9 48.4 15.4 1.9 5.1 2.8 90.0 52.8 4.7 4.3 4.0 30.9 4.0 76.4 47.6 18.5 39.0 14.6 64.8 16.7 5.4 27.7 55.3 31.7 4.4 37.1 4.9 53.1 0.9 2.6 56.8 2.5 69.2 14.4 120.6 0.0 0.0 1.5 0.0 51.1 25.8 0.2 1.8 3.6 6.6 14.7 0.4 0.0 0.3 3.9 4.5 13.6 0.0 0.1 0.0 18.0 0.4 2.9 6.3 3.7 0.0 8.5 0.1 0.3 28.7 0.1 26.7 0.7 15.1 14.4 0.4 0.0 20.8 83.2 0.1 4.6 1.8 4.0 0.0 0.0 0.5 71.5 0.3 40.1 0.0 17.4 0.0 0.0 0.3 4.9 2.8 0.1 0.7 11.9 14.2 0.7 34.9 1.2 22.2 3.2 0.0 11.5 0.3 0.0 0.3 0.5 0.1 0.0 0.6 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.4 0.3 0.2 0.1 0.0 0.2 26.9 82.9 49.5 54.7 26.9 48.4 90.0 52.8 76.4 31.7 53.1 120.6 0.4 0.0 1.1 27.7 0.0 2.3 0.4 0.5 0.0 47.5 1.2 3.4 11.1 0.0 1.0 11.0 0.0 0.0 1.6 3.5 1.9 0.0 12.6 37.7 4.7 3.7 54.3 0.0 152.4 0.5 0.2 2.9 3.1 34.7 0.0 0.1 21.8 0.2 3.2 15.2 65.4 36.4 4.1 3.1 3.1 30.0 0.9 2.3 5.4 13.1 1.7 9.9 2.1 134.7 918.7 0.4 8.8 1.5 0.1 5.1 9.9 20.3 17.0 6.5 0.0 27.2 9.6 4.3 4.2 0.0 1.4 0.0 0.7 0.5 5.2 0.6 PTK6 BRK ENSG00000101213 "Protein tyrosine kinase 6" Q13882 20 63528001-63537376 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 109.4;skin 1: 53.9;vagina: 43.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 132.1;Gastric mucus-secreting cells: 59.1;Intestinal goblet cells: 42.5;Paneth cells: 97.6;Proximal enterocytes: 80.2;Squamous epithelial cells: 48.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "A-431: 22.1;CAPAN-2: 41.4;HaCaT: 33.9;hTCEpi: 45.0;OE19: 57.0;RT4: 26.4;T-47d: 25.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB032952, HPA036070, HPA036071" Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nuclear bodies, Plasma membrane, Cytosol" "CAB032952: AB_634461, HPA036070: AB_10602292, HPA036071: AB_10669982" "unprognostic (2.32e-2)" "unprognostic (1.36e-1)" "unprognostic (1.05e-1)" "unprognostic (2.42e-2)" "unprognostic (1.41e-1)" "unprognostic (1.35e-1)" "unprognostic (1.04e-1)" "unprognostic (2.29e-1)" "unprognostic (3.03e-1)" "unprognostic (3.72e-2)" "prognostic unfavorable (1.96e-4)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.26e-9)" "unprognostic (4.19e-2)" "unprognostic (1.74e-1)" "unprognostic (1.73e-1)" "unprognostic (4.24e-2)" 0.5 0.1 0.6 3.6 1.7 0.8 3.8 2.9 1.7 19.8 0.0 26.5 28.9 0.4 0.1 109.4 0.4 3.5 0.2 0.6 0.9 0.8 5.2 2.6 0.6 1.6 1.0 0.3 3.6 0.0 0.2 0.3 1.7 3.1 15.7 0.8 19.1 0.6 0.6 53.9 22.2 0.8 0.6 0.8 26.2 0.3 1.1 0.3 0.2 0.0 6.4 9.8 43.2 5.4 22.1 2.6 0.3 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.5 41.4 0.1 7.2 0.0 0.1 33.9 0.0 0.1 0.0 5.4 0.4 0.0 10.2 0.1 0.1 0.0 6.7 0.0 45.0 0.0 0.2 0.2 0.0 0.1 0.2 2.5 0.2 12.5 0.0 0.2 0.2 57.0 15.5 0.1 1.2 0.5 0.0 26.4 0.3 2.2 2.6 8.1 0.0 0.1 25.2 1.6 0.2 0.3 0.4 0.8 0.3 0.5 0.1 0.1 0.4 0.5 1.1 0.4 0.7 0.1 0.1 0.5 0.5 0.3 0.1 0.0 1.3 0.3 0.1 0.1 0.3 0.0 0.4 0.1 0.1 0.3 0.6 1.7 2.9 1.7 0.6 0.9 1.6 1.0 1.7 0.6 1.1 5.4 0.3 12.8 25.6 0.3 1.4 5.9 2.6 7.7 5.2 2.2 7.0 4.3 0.4 12.8 14.9 0.0 2.1 0.2 0.2 132.1 0.0 1.4 0.2 0.4 0.5 3.2 5.4 0.0 0.1 1.6 0.2 1.4 59.1 1.3 9.5 0.2 0.4 1.7 0.6 0.0 0.1 42.5 2.0 2.2 2.0 0.0 0.3 2.6 0.0 0.0 1.0 1.6 1.0 0.0 0.8 17.6 97.6 0.0 0.1 1.5 80.2 0.2 8.9 3.7 0.0 2.3 1.1 0.2 0.3 48.0 15.5 0.1 2.0 0.2 32.1 15.9 PTPN11 "BPTP3, NS1, PTP2C, SH-PTP2, SHP-2, SHP2" ENSG00000179295 "Protein tyrosine phosphatase non-receptor type 11" Q06124 12 112418351-112509918 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005377 Approved Supported "Nucleoplasm,Nucleoli rim,Actin filaments,Cytosol" NA NA 74000 "Cluster 6: Non-specific - Transcription" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Nucleoli rim" "Actin filaments, Cytosol" "CAB005377: AB_632401" "unprognostic (2.18e-3)" "unprognostic (1.73e-3)" "unprognostic (5.62e-2)" "unprognostic (1.19e-1)" "unprognostic (1.63e-2)" "unprognostic (2.27e-1)" "unprognostic (6.05e-2)" "unprognostic (4.25e-2)" "unprognostic (3.55e-2)" "unprognostic (1.88e-1)" "unprognostic (2.22e-2)" "unprognostic (8.85e-2)" "unprognostic (3.75e-3)" "unprognostic (1.66e-1)" "unprognostic (2.46e-1)" "unprognostic (3.62e-2)" "unprognostic (1.80e-2)" 62.9 36.6 74.6 34.7 91.7 46.3 37.6 72.7 115.7 37.9 38.4 32.5 27.6 37.8 28.7 38.9 24.3 29.4 68.7 66.1 85.6 39.7 53.0 34.4 35.6 79.0 84.1 26.2 31.6 53.4 16.1 38.0 85.7 35.2 30.6 51.8 25.9 42.4 75.1 32.1 26.1 45.7 83.4 26.7 30.4 18.2 81.7 35.5 46.8 64.0 32.5 40.1 23.5 106.3 116.9 107.6 77.0 73.4 109.7 106.1 92.7 136.4 148.2 105.5 78.5 107.7 43.4 124.5 69.4 127.4 66.7 68.1 100.1 121.6 173.8 93.1 85.0 181.5 102.6 59.8 109.2 145.8 108.0 86.6 119.6 113.6 159.8 101.3 88.7 92.0 140.2 41.3 103.3 83.2 101.0 69.7 94.1 112.3 73.4 102.4 114.6 70.5 97.3 126.7 53.3 66.1 133.7 99.8 85.2 77.6 114.8 97.8 108.1 122.9 110.0 74.2 121.8 79.4 141.6 120.2 102.2 99.7 117.7 32.2 11.7 16.8 14.8 10.2 14.0 18.1 13.3 12.4 13.6 20.8 15.3 11.9 10.7 12.6 13.7 18.3 10.9 7.2 74.6 91.7 72.7 115.7 66.1 85.6 79.0 84.1 85.7 83.4 81.7 106.3 49.0 60.9 68.2 27.7 25.8 25.6 39.9 25.3 20.5 29.9 40.5 32.4 131.6 24.3 41.8 36.8 16.7 23.5 34.2 25.4 33.2 37.5 63.1 31.3 92.6 46.2 13.1 21.7 67.6 42.8 25.3 35.8 21.9 40.9 28.4 33.1 26.0 101.5 26.8 13.5 54.7 22.0 18.3 33.3 21.6 28.5 51.6 31.8 14.2 40.3 31.1 59.8 29.9 32.6 73.0 59.3 19.6 79.7 37.0 73.4 16.6 39.8 23.5 22.2 32.9 58.2 49.2 7.1 6.6 37.5 27.4 35.2 31.7 30.5 22.2 66.8 PYM1 "PYM, WIBG" ENSG00000170473 "PYM homolog 1, exon junction complex associated factor" Q9BRP8 12 55901413-55932618 "Predicted intracellular proteins" "Nonsense-mediated mRNA decay, Translation regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 110.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012803, HPA039717, HPA046200" Supported Supported "Nucleoplasm,Nucleoli,Cell Junctions,Cytosol" No No 27000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 43: THP-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli, Cytosol" "Cell Junctions" "CAB012803: AB_2269494, HPA039717: AB_2676644, HPA046200: AB_10965556" "unprognostic (3.03e-2)" "unprognostic (1.00e-1)" "unprognostic (5.65e-2)" "unprognostic (8.82e-2)" "unprognostic (1.97e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (3.05e-4)" "unprognostic (3.29e-1)" "unprognostic (2.17e-3)" "unprognostic (2.44e-2)" "unprognostic (3.94e-2)" "unprognostic (1.29e-1)" "unprognostic (1.32e-2)" "unprognostic (1.59e-2)" "unprognostic (2.22e-1)" "unprognostic (1.29e-1)" "prognostic favorable (1.34e-4)" 24.5 30.8 19.8 24.0 20.2 22.5 27.9 21.5 24.8 26.1 22.9 31.1 31.6 22.1 41.5 72.3 22.7 19.8 21.8 19.5 20.7 26.3 43.0 20.8 35.4 20.5 20.6 17.1 28.0 26.3 22.3 22.8 20.5 31.2 30.0 17.4 34.0 15.9 29.8 41.9 29.5 19.8 20.1 31.1 24.1 25.9 20.1 33.2 27.0 29.0 42.1 24.8 31.4 20.2 50.3 39.1 56.1 31.4 33.4 43.2 92.6 36.1 43.1 33.3 28.0 57.7 57.9 62.9 53.6 35.1 15.4 38.6 43.6 77.1 26.7 48.6 32.7 51.0 35.1 71.8 40.7 59.7 44.7 39.2 48.8 37.7 56.0 42.2 35.9 27.3 44.5 67.4 39.7 75.3 38.6 105.7 98.3 56.7 20.2 34.3 22.3 72.5 69.5 69.8 37.7 43.4 46.2 61.1 33.1 51.8 74.5 124.0 28.2 20.0 28.3 31.5 26.6 35.5 58.2 97.2 34.2 40.9 31.9 17.5 79.8 75.8 58.5 92.2 72.3 98.1 105.4 82.2 120.2 88.2 68.7 69.5 19.1 53.1 66.5 65.6 186.0 87.2 19.8 20.2 21.5 24.8 19.5 20.7 20.5 20.6 20.5 20.1 20.1 20.2 16.2 19.2 17.3 0.0 28.6 0.0 29.4 0.0 21.1 12.7 41.7 38.4 0.0 25.8 14.2 23.9 8.4 84.3 21.1 29.8 78.2 40.6 15.2 21.1 17.0 16.3 7.3 32.2 0.0 50.6 76.3 17.6 22.4 21.1 18.9 14.5 22.9 44.3 55.2 6.7 0.0 32.1 0.0 47.7 0.0 11.7 23.3 42.8 0.0 0.0 110.4 55.7 48.4 0.0 0.0 54.1 33.7 23.7 21.9 34.7 66.8 61.3 16.8 13.6 13.1 18.0 15.7 23.8 25.6 63.1 0.0 62.0 29.6 16.5 29.3 34.3 RAB11FIP3 "eferin, KIAA0665, Rab11-FIP3" ENSG00000090565 "RAB11 family interacting protein 3" O75154 16 425649-523011 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 151.1" "Cell type enriched" "Detected in many" 5 "Proximal tubular cells: 384.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028088, HPA028631, HPA030086" Enhanced Enhanced "Nucleoplasm,Vesicles,Cytokinetic bridge,Centriolar satellite,Mitochondria" Yes No "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Centriolar satellite" "Nucleoplasm, Cytokinetic bridge, Mitochondria" "HPA028088: AB_10601672, HPA028631: AB_10601853, HPA030086: AB_10669596" "unprognostic (6.65e-2)" "unprognostic (1.84e-2)" "unprognostic (1.51e-1)" "prognostic favorable (1.22e-4)" "unprognostic (2.87e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (9.87e-5)" "unprognostic (6.71e-2)" "unprognostic (4.74e-1)" "unprognostic (9.66e-2)" "prognostic favorable (3.16e-5)" "unprognostic (1.12e-1)" "prognostic favorable (7.99e-4)" "unprognostic (1.39e-1)" "unprognostic (1.77e-1)" "unprognostic (1.58e-1)" "unprognostic (1.44e-1)" 27.9 32.3 18.0 5.3 18.9 7.0 19.5 21.3 22.6 29.6 7.6 35.1 9.0 31.3 5.5 12.3 27.5 7.4 31.4 21.7 14.0 151.1 37.3 25.2 5.8 14.4 15.8 33.8 47.4 15.9 41.5 6.5 15.2 29.9 3.1 6.1 19.3 7.8 52.2 19.5 27.5 7.1 12.7 26.4 22.2 34.6 16.8 5.3 24.8 15.8 3.2 31.7 19.9 19.0 5.9 14.9 14.6 11.9 20.2 13.2 10.0 10.6 11.6 10.7 7.6 11.5 3.0 15.3 11.0 18.7 8.9 5.5 8.9 13.4 3.9 10.8 14.9 7.9 14.8 31.7 20.9 9.5 8.6 12.7 8.8 11.6 9.9 11.7 17.3 10.7 3.5 6.0 14.4 22.5 10.2 15.9 11.7 5.0 6.8 22.8 10.8 4.6 11.3 4.0 13.8 12.0 11.5 13.6 7.5 5.0 7.6 13.9 29.9 14.8 8.8 13.6 7.0 6.9 6.7 18.8 6.5 5.8 11.7 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 18.0 18.9 21.3 22.6 21.7 14.0 14.4 15.8 15.2 12.7 16.8 19.0 9.4 3.2 1.7 36.9 3.8 3.7 0.7 1.1 2.2 7.7 3.5 4.3 12.4 7.2 4.3 5.5 6.2 1.0 5.7 5.9 27.4 1.6 1.2 6.4 8.7 7.1 3.0 1.7 73.5 1.2 0.2 5.5 2.0 13.1 1.3 8.4 17.9 15.9 0.8 21.9 60.3 3.0 0.0 3.7 1.6 2.6 0.6 4.7 0.0 19.7 0.6 7.2 2.1 46.8 40.7 1.4 3.9 1.9 3.4 0.9 8.1 384.2 3.1 7.6 6.6 5.3 5.4 4.0 2.8 0.3 2.3 0.8 4.4 6.1 5.9 0.3 RAD51C "FANCO, RAD51L2" ENSG00000108384 "RAD51 paralog C" O43502 17 58692573-58735611 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 117.7;Spermatocytes: 140.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 319.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA045198 Supported "Nucleoplasm,Vesicles,Cell Junctions,Mitochondria,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Mitochondria, Cytosol" "Vesicles, Cell Junctions" "HPA045198: AB_2679250" "unprognostic (5.39e-3)" "unprognostic (2.39e-2)" "unprognostic (1.23e-2)" "unprognostic (6.20e-2)" "unprognostic (1.83e-1)" "unprognostic (4.59e-2)" "prognostic unfavorable (8.68e-5)" "unprognostic (3.65e-2)" "unprognostic (2.91e-2)" "unprognostic (1.03e-2)" "prognostic favorable (5.33e-4)" "unprognostic (2.55e-1)" "unprognostic (2.62e-2)" "unprognostic (7.62e-2)" "unprognostic (2.41e-1)" "unprognostic (9.52e-2)" "unprognostic (2.42e-2)" 10.8 20.2 15.5 10.0 15.7 23.1 15.3 19.0 18.4 10.8 13.4 12.4 7.5 12.6 22.0 13.0 11.2 11.0 25.7 16.4 15.0 12.8 13.3 8.8 22.0 14.9 13.8 12.5 10.6 20.1 10.5 15.1 16.0 17.4 14.5 13.5 10.7 12.0 18.3 10.6 8.7 13.8 13.2 12.2 11.6 20.2 14.6 21.2 12.3 17.3 19.1 10.9 8.6 18.2 63.7 72.1 43.3 48.5 22.9 19.6 100.1 34.2 14.5 43.5 55.3 31.0 39.3 37.4 48.9 23.5 58.8 23.3 59.5 46.6 81.7 91.6 123.0 53.0 84.6 119.4 23.3 69.1 45.0 12.1 42.2 47.8 38.6 24.0 50.0 60.9 83.6 48.5 37.0 319.1 96.8 95.3 12.1 42.5 66.5 62.1 69.5 69.8 26.9 39.6 54.3 49.6 27.3 12.0 53.5 11.1 39.2 71.6 16.5 37.6 100.1 34.3 42.4 44.1 187.2 111.5 38.3 67.1 42.0 27.6 9.2 12.5 15.6 14.3 15.2 18.0 16.9 17.2 15.9 17.3 18.2 17.4 5.1 15.0 12.5 14.3 27.1 11.0 15.5 15.7 19.0 18.4 16.4 15.0 14.9 13.8 16.0 13.2 14.6 18.2 20.5 19.2 13.9 10.1 20.5 11.9 18.7 42.9 15.9 15.0 25.1 34.0 63.7 7.2 20.9 16.5 6.2 67.8 15.0 7.1 58.7 25.7 117.7 17.3 13.0 19.3 6.7 43.8 21.5 18.6 94.1 19.8 7.1 13.0 22.9 23.3 15.7 15.7 33.4 16.8 17.7 11.7 32.6 16.1 47.7 65.4 17.4 21.8 24.9 13.1 18.7 31.3 21.6 23.1 22.8 13.0 10.4 15.4 28.5 17.2 5.7 24.6 14.1 26.9 32.9 14.7 23.9 140.7 98.3 15.9 10.7 36.3 20.5 28.2 15.3 13.9 RANBP17 ENSG00000204764 "RAN binding protein 17" Q9H2T7 5 170861870-171300015 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.3" "Cell type enhanced" "Detected in many" "Early spermatids: 112.7;Excitatory neurons: 100.6;Glandular and luminal cells: 59.5;Inhibitory neurons: 152.9;Oligodendrocyte precursor cells: 65.4;Oligodendrocytes: 87.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 4.0;SK-BR-3: 3.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029568, HPA029569" Uncertain Approved "Nucleoplasm,Nuclear membrane,Nuclear bodies,Cytosol" Yes No "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Nuclear bodies" "Nuclear membrane, Cytosol" "HPA029568: AB_10599825, HPA029569: AB_10601571" "unprognostic (4.63e-2)" "unprognostic (2.63e-3)" "unprognostic (1.06e-1)" "unprognostic (8.28e-2)" "unprognostic (1.75e-3)" "unprognostic (5.12e-3)" "unprognostic (1.50e-1)" "unprognostic (2.45e-1)" "unprognostic (1.31e-1)" "unprognostic (2.00e-1)" "unprognostic (1.54e-1)" "unprognostic (9.59e-2)" "unprognostic (1.64e-2)" "unprognostic (2.19e-3)" "unprognostic (2.72e-1)" "unprognostic (1.35e-1)" "unprognostic (2.56e-3)" 0.2 0.8 0.3 0.1 0.2 0.1 0.2 2.3 0.6 0.2 0.8 0.2 0.2 0.5 0.2 0.0 0.4 0.5 0.2 0.1 1.1 0.4 0.3 0.8 0.3 0.9 0.9 0.2 1.4 0.8 0.4 0.8 1.3 0.4 0.4 0.8 0.8 0.5 0.0 0.1 0.3 0.3 0.6 0.0 0.3 1.4 0.6 0.2 1.0 0.0 0.1 0.1 0.1 1.1 0.0 0.7 4.0 3.3 1.3 0.3 2.4 2.6 1.2 1.8 1.1 1.5 0.0 0.1 2.0 2.5 0.0 0.0 0.0 1.2 3.5 0.0 2.4 0.7 1.4 0.0 1.1 0.0 0.0 2.6 0.2 0.2 0.0 0.2 1.7 0.0 0.3 0.0 1.0 1.7 0.0 0.0 0.3 0.6 0.2 0.0 2.4 0.0 0.6 1.0 0.2 1.4 0.0 3.9 1.5 1.7 0.7 1.2 2.4 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 2.3 0.6 0.1 1.1 0.9 0.9 1.3 0.6 0.6 1.1 9.4 9.6 2.0 12.7 0.0 0.3 6.2 5.8 1.8 24.8 6.1 2.8 1.3 7.2 4.8 0.0 14.6 10.4 1.7 2.3 0.0 7.3 112.7 22.4 17.5 7.9 5.4 5.5 100.6 1.4 3.2 4.9 5.1 59.5 0.0 15.6 4.2 1.6 1.9 0.0 152.9 3.7 2.0 0.6 1.4 46.5 2.8 1.0 1.8 9.4 1.2 5.5 5.2 65.4 87.1 5.3 2.9 3.0 0.8 13.0 3.9 0.9 2.4 26.9 0.0 3.0 5.1 27.2 26.7 1.4 0.0 2.5 0.8 7.5 6.3 7.6 RARA "NR1B1, RAR" ENSG00000131759 "Retinoic acid receptor alpha" P10276 17 40309180-40357643 "Cancer-related genes, Disease related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 52.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 221.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058282, HPA071548" Supported "Nucleoplasm,Nucleoli,Actin filaments,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 41: Macrophages - Immune response" Nucleoplasm "Nucleoli, Actin filaments, Cytosol" "HPA058282: AB_2683666, HPA071548: " "unprognostic (8.05e-3)" "unprognostic (1.89e-1)" "unprognostic (9.48e-3)" "prognostic favorable (2.60e-4)" "unprognostic (8.67e-3)" "unprognostic (4.87e-3)" "unprognostic (2.77e-1)" "unprognostic (5.73e-2)" "unprognostic (1.45e-1)" "unprognostic (3.54e-2)" "unprognostic (1.19e-1)" "unprognostic (1.79e-1)" "unprognostic (2.29e-3)" "unprognostic (1.59e-2)" "unprognostic (5.60e-2)" "unprognostic (1.60e-1)" "unprognostic (1.09e-2)" 47.6 21.1 3.2 28.3 4.4 59.6 37.2 7.2 16.5 43.7 5.1 31.0 28.4 32.2 10.7 14.9 40.7 41.3 40.8 7.0 5.7 24.1 42.3 58.4 16.4 5.3 2.7 40.8 14.7 11.3 30.6 25.7 2.8 29.8 13.2 18.3 20.6 21.3 62.6 24.8 32.2 28.6 1.8 41.7 22.9 28.8 4.9 10.0 26.9 17.4 11.8 30.3 30.2 4.3 18.0 41.9 11.8 20.5 23.4 35.9 12.5 14.9 21.8 21.5 13.6 28.6 15.1 9.6 22.7 33.2 18.9 51.1 14.2 33.9 12.0 77.5 21.4 26.6 21.2 29.8 37.0 9.4 81.3 48.2 10.0 22.7 29.2 75.8 30.9 8.4 17.6 20.2 23.7 221.5 6.4 34.2 10.7 16.2 13.3 12.9 71.3 37.0 12.2 14.4 5.4 40.5 31.0 124.8 42.1 11.7 119.1 36.6 35.8 25.3 45.3 44.2 15.4 48.7 16.9 8.3 38.4 18.7 77.1 26.3 8.9 34.6 3.2 14.6 5.1 2.0 3.6 3.8 12.4 1.7 1.5 2.8 52.6 5.9 19.5 3.8 3.1 5.0 3.2 4.4 7.2 16.5 7.0 5.7 5.3 2.7 2.8 1.8 4.9 4.3 35.6 3.2 7.0 2.3 43.4 19.5 25.6 8.4 18.8 23.2 35.4 17.5 3.8 10.0 5.5 7.3 6.2 2.2 36.9 41.2 13.7 16.7 60.5 20.7 22.0 28.4 9.6 5.7 5.4 19.2 5.8 28.5 10.7 18.4 35.5 13.9 26.0 28.8 12.3 3.3 2.6 13.1 6.1 45.4 65.5 66.2 41.7 56.9 28.4 2.8 26.1 11.8 6.2 4.0 0.3 22.0 33.1 23.0 21.0 13.4 70.9 17.7 4.9 10.2 32.9 42.1 26.7 3.6 7.6 7.1 18.9 5.2 31.7 6.5 16.5 19.3 RASSF2 "CENP-34, KIAA0168" ENSG00000101265 "Ras association domain family member 2" P50749 20 4780023-4823608 "Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 217.0;retina: 162.8" "Cell type enhanced" "Detected in many" "Kupffer cells: 87.1;Langerhans cells: 75.8;monocytes: 148.5;Oligodendrocytes: 106.7;Peritubular cells: 149.7;Rod photoreceptor cells: 160.3" "Cancer enriched" "Detected in all" 5 "glioma: 48.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AN3-CA: 56.8;BEWO: 59.2;Daudi: 62.7;HL-60: 74.7;NB-4: 96.3;U-937: 116.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051200 Uncertain Supported "Nucleoplasm,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 32: U-937 - Innate immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm "Golgi apparatus, Plasma membrane, Cytosol" "HPA051200: AB_2681386" "unprognostic (6.51e-2)" "unprognostic (3.67e-3)" "unprognostic (5.31e-2)" "unprognostic (1.47e-2)" "unprognostic (3.15e-1)" "unprognostic (1.46e-3)" "unprognostic (2.80e-1)" "unprognostic (7.01e-2)" "unprognostic (1.38e-2)" "unprognostic (2.41e-2)" "unprognostic (4.93e-2)" "unprognostic (3.90e-1)" "prognostic unfavorable (7.82e-4)" "unprognostic (3.51e-2)" "unprognostic (1.35e-1)" "unprognostic (3.49e-1)" "unprognostic (6.46e-2)" 16.4 9.7 76.1 47.1 135.2 91.2 6.9 155.5 113.5 27.9 40.0 8.4 5.3 25.4 22.5 10.0 22.1 15.6 4.2 68.9 94.7 4.0 5.9 25.4 58.6 217.0 148.8 7.0 3.1 1.5 5.0 9.1 186.4 7.3 9.6 162.8 3.0 9.3 1.2 4.2 14.5 38.7 135.8 32.7 7.0 20.6 120.0 19.5 4.7 5.0 73.6 20.7 4.9 197.0 0.1 14.5 34.9 56.8 0.4 0.0 59.2 3.5 10.0 0.6 0.2 3.4 0.1 62.7 5.6 3.1 1.4 0.2 5.1 0.0 0.8 22.7 2.1 41.1 0.0 0.7 0.0 74.7 40.1 0.1 0.0 1.3 0.0 1.3 23.4 7.0 0.2 24.0 0.0 0.1 11.0 96.3 7.8 0.0 1.1 17.1 3.9 23.8 0.0 29.0 0.4 2.8 0.0 1.0 1.7 7.4 0.0 47.0 0.7 1.5 7.4 0.7 4.6 0.3 5.9 37.8 0.3 116.8 0.4 85.6 61.5 101.3 7.7 50.1 14.6 24.3 12.0 10.4 46.8 16.4 7.8 6.5 139.5 8.5 59.9 30.7 11.8 42.1 76.1 135.2 155.5 113.5 68.9 94.7 217.0 148.8 186.4 135.8 120.0 197.0 5.5 0.0 8.7 7.5 49.3 4.7 0.0 0.1 0.0 39.2 4.1 1.7 1.9 1.5 1.9 0.0 27.1 3.0 43.0 0.1 1.9 1.2 6.0 3.2 19.6 18.6 0.0 6.1 1.5 0.9 5.1 10.9 1.1 1.0 54.3 4.5 11.4 1.2 27.1 6.7 1.3 0.7 0.0 87.1 75.8 25.1 33.2 64.6 8.8 26.2 148.5 19.3 7.2 33.7 106.7 0.6 0.0 149.7 14.3 1.2 0.0 0.3 0.1 160.3 0.0 9.4 3.5 0.7 1.0 0.3 2.6 1.4 20.8 0.8 0.0 2.3 RASSF4 "AD037, MGC44914" ENSG00000107551 "Ras association domain family member 4" Q9H2L5 10 44959407-44995891 "Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 77.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 157.0;monocytes: 258.7;Muller glia cells: 260.3;Proximal tubular cells: 128.0;Skeletal myocytes: 186.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 84.8;intermediate monocyte: 63.9;myeloid DC: 84.2;non-classical monocyte: 37.9" "Group enriched" "Detected in many" 10 "dendritic cells: 84.2;monocytes: 84.8" "Cell line enhanced" "Detected in many" "Karpas-707: 64.3;RH-30: 162.7;RPMI-8226: 54.9;U-937: 85.4;WM-115: 54.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038834, HPA077069" Approved Approved "Nucleoplasm,Nucleoli,Cell Junctions,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 5: Muller glia cells - Visual perception" "Nucleoplasm, Nucleoli" "Cell Junctions, Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA038834: AB_10795576, HPA077069: " "unprognostic (1.83e-1)" "unprognostic (8.21e-3)" "unprognostic (1.21e-2)" "unprognostic (1.04e-1)" "unprognostic (1.25e-1)" "unprognostic (5.14e-2)" "unprognostic (3.15e-2)" "unprognostic (2.18e-2)" "unprognostic (8.81e-2)" "unprognostic (4.83e-2)" "unprognostic (8.75e-3)" "unprognostic (4.20e-1)" "unprognostic (4.11e-3)" "unprognostic (4.02e-2)" "unprognostic (2.22e-2)" "unprognostic (1.42e-1)" "unprognostic (6.20e-2)" 35.3 7.1 57.4 21.7 67.9 8.3 22.7 64.3 58.6 6.5 43.8 18.5 13.6 3.0 8.6 4.7 6.0 10.8 44.8 53.9 58.9 77.3 17.1 11.9 19.7 63.4 64.0 3.6 39.5 5.0 13.0 12.7 65.9 7.9 6.0 26.9 16.7 10.9 14.8 4.8 13.8 8.7 55.8 20.1 9.4 9.0 65.3 10.4 40.7 17.6 9.1 11.4 7.0 69.7 1.4 0.3 6.0 11.4 17.9 1.0 4.1 0.7 1.1 2.0 3.5 5.0 0.6 0.1 2.3 0.8 3.9 0.0 2.6 2.8 2.8 37.8 0.0 0.1 0.2 39.7 19.0 2.6 0.0 13.1 0.0 1.9 0.2 10.9 3.0 1.6 0.0 64.3 2.9 0.0 3.0 43.1 1.2 0.2 1.2 8.1 162.7 54.9 0.4 1.2 1.0 0.8 0.0 0.5 2.0 10.7 1.1 32.4 0.0 0.4 3.6 3.0 6.5 0.7 0.7 0.1 18.9 85.4 54.8 0.0 84.8 0.1 8.7 63.9 0.2 0.0 0.6 3.7 84.2 0.0 0.6 2.6 3.0 6.9 37.9 2.2 0.3 48.9 57.4 67.9 64.3 58.6 53.9 58.9 63.4 64.0 65.9 55.8 65.3 69.7 8.9 19.2 17.2 77.4 3.7 3.7 1.4 3.2 1.2 22.5 9.7 7.0 47.9 37.1 13.1 16.5 4.2 1.2 20.3 10.1 17.6 45.3 1.4 6.4 13.7 9.2 11.5 0.0 17.0 3.8 1.2 28.6 1.5 14.8 1.3 4.2 6.1 20.1 157.0 37.0 33.6 7.4 12.2 84.7 94.3 4.4 10.5 91.0 8.8 35.6 258.7 260.3 54.6 37.7 38.2 4.0 11.3 2.2 4.1 1.0 45.0 128.0 5.9 13.3 26.3 186.4 25.9 0.6 1.9 0.8 1.7 2.6 8.0 4.9 15.0 0.7 RBFOX1 "A2BP1, FOX-1, HRNBP1" ENSG00000078328 "RNA binding fox-1 homolog 1" Q9NWB1 16 5239802-7713340 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "brain: 73.9;heart muscle: 25.2;skeletal muscle: 95.3;tongue: 45.3" "Group enriched" "Detected in some" 8 "Excitatory neurons: 5800.8;Inhibitory neurons: 5921.8" "Cancer enhanced" "Detected in single" "glioma: 0.7" "Group enriched" "Detected in many" 10 "basal ganglia: 28.1;cerebral cortex: 73.9;hippocampal formation: 26.6;white matter: 22.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "RH-30: 25.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040809, HPA066746, HPA075862" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus,Cytosol" No No "Cluster 11: Basophils - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Nucleoli fibrillar center, Golgi apparatus, Cytosol" "HPA040809: AB_10796228, HPA066746: , HPA075862: " "unprognostic (3.75e-3)" "unprognostic (2.11e-1)" "unprognostic (1.59e-1)" "unprognostic (1.76e-2)" "unprognostic (5.19e-3)" "unprognostic (8.82e-5)" "unprognostic (5.02e-1)" "unprognostic (3.08e-1)" "unprognostic (1.47e-1)" "unprognostic (1.43e-2)" "unprognostic (3.24e-2)" "unprognostic (2.23e-1)" "unprognostic (5.00e-2)" "unprognostic (2.28e-1)" 0.3 1.5 3.7 0.4 28.1 0.5 0.1 2.5 73.9 0.6 0.0 0.8 0.2 0.2 3.1 1.1 1.1 0.1 25.2 26.6 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.2 0.2 0.0 1.1 0.1 0.0 1.7 0.5 5.7 2.2 4.1 95.3 0.3 0.2 0.0 2.7 0.0 0.2 1.1 2.2 0.2 0.1 45.3 0.0 0.4 0.4 22.6 0.1 0.2 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.2 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 1.7 0.0 0.0 0.1 1.6 0.0 0.0 0.0 25.9 0.0 0.0 0.1 0.3 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.2 0.4 0.1 0.1 0.2 0.0 0.2 0.2 0.3 0.0 0.7 0.1 0.4 0.2 0.0 0.1 0.2 0.2 0.2 0.0 0.3 0.3 0.2 0.7 0.2 0.1 0.1 0.2 0.0 3.7 28.1 2.5 73.9 26.6 0.0 0.0 0.0 0.0 2.7 2.2 22.6 0.0 0.0 0.5 97.9 0.0 0.0 0.0 0.0 0.0 10.9 0.4 0.0 98.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 6.6 0.3 1.8 0.9 0.0 0.0 5800.8 0.2 0.0 3.5 0.0 0.1 0.0 47.8 0.0 0.0 0.1 0.0 5921.8 0.5 0.0 0.0 0.3 4.9 1.2 0.5 1.8 132.1 0.6 6.6 0.0 597.6 689.4 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.7 2.8 0.0 17.0 1.2 0.6 0.5 0.0 0.0 0.0 0.1 0.7 0.7 0.0 RBL2 "p130, Rb2" ENSG00000103479 "RB transcriptional corepressor like 2" Q08999 16 53433977-53491648 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 468.3;Late spermatids: 209.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016547, HPA019703" Supported Supported "Nucleoplasm,Nucleoli rim,Mitotic chromosome,Cytosol" Yes No "Cluster 48: NK-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 58: T-cells - T-cell receptor" "Nucleoplasm, Nucleoli rim, Mitotic chromosome" Cytosol "CAB016547: AB_785011, HPA019703: AB_1856106" "unprognostic (1.51e-1)" "unprognostic (4.38e-2)" "unprognostic (4.00e-2)" "unprognostic (1.26e-1)" "unprognostic (6.88e-2)" "unprognostic (6.43e-2)" "unprognostic (5.03e-2)" "unprognostic (2.46e-2)" "unprognostic (1.04e-1)" "unprognostic (2.11e-1)" "unprognostic (4.70e-1)" "unprognostic (8.12e-2)" "prognostic favorable (3.57e-5)" "unprognostic (9.57e-3)" "unprognostic (1.02e-1)" "unprognostic (8.70e-2)" "unprognostic (7.51e-2)" 32.5 25.4 11.1 32.3 13.6 19.1 31.7 12.5 10.4 33.5 14.8 26.6 23.3 32.2 20.2 25.0 31.8 27.7 25.6 8.7 10.5 39.2 59.5 38.9 49.7 12.3 12.0 37.8 39.0 62.7 17.7 19.3 13.0 42.9 29.3 23.1 34.2 39.9 32.4 26.3 26.1 30.7 11.7 41.0 32.6 48.4 11.4 66.6 40.2 37.7 51.2 30.9 28.9 16.9 25.9 18.1 20.7 20.6 61.2 57.9 9.4 17.8 26.4 23.1 7.9 10.1 30.9 39.0 28.4 32.8 22.3 29.6 17.9 30.1 36.0 12.5 22.4 15.9 14.7 22.0 27.3 23.4 49.0 35.6 34.0 15.3 22.4 43.0 36.3 39.6 12.7 23.2 26.6 7.1 48.6 22.0 7.8 30.8 15.0 33.6 41.8 46.1 25.4 25.3 16.9 14.3 42.2 17.2 19.1 16.8 22.7 30.0 28.3 27.5 14.3 24.1 13.7 35.7 22.9 42.4 34.4 28.2 19.0 53.9 22.5 56.5 53.4 16.2 60.5 22.5 59.7 62.8 21.7 22.0 85.5 75.3 41.8 74.4 28.8 13.1 48.2 76.2 11.1 13.6 12.5 10.4 8.7 10.5 12.3 12.0 13.0 11.7 11.4 16.9 37.9 41.7 101.1 51.2 49.5 23.1 30.1 15.3 40.9 27.8 27.0 15.5 13.5 45.8 32.5 27.6 20.9 6.0 77.0 26.3 17.6 13.4 468.3 38.9 25.8 31.4 19.8 26.5 55.1 10.2 13.0 35.8 24.5 45.9 55.1 27.9 40.7 46.1 11.2 35.3 54.1 30.0 34.6 43.6 23.7 209.1 42.0 35.4 10.6 58.1 44.9 38.3 79.3 63.3 85.7 10.8 19.0 42.9 48.7 31.4 29.2 25.3 38.3 22.5 39.5 36.2 26.1 161.4 61.3 33.7 27.6 4.1 118.9 25.2 21.7 35.6 RBM20 ENSG00000203867 "RNA binding motif protein 20" Q5T481 10 110644336-110839468 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 40.8;pancreas: 20.2" "Cell type enriched" "Detected in many" 8 "Cardiomyocytes: 151.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 6.0;HEL: 5.2;K-562: 5.0;RH-30: 16.2;SH-SY5Y: 15.0;SuSa: 4.9;T-47d: 9.2" "Low region specificity" "Detected in single" "HPA035806, HPA070358" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Cytokinetic bridge" Yes No "Cluster 38: Heart - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Golgi apparatus" "Nucleoli, Cytokinetic bridge" "HPA035806: AB_10672097, HPA070358: " "unprognostic (2.43e-1)" "unprognostic (8.24e-3)" "unprognostic (5.81e-2)" "unprognostic (1.27e-2)" "unprognostic (1.03e-1)" "unprognostic (2.03e-2)" "unprognostic (2.75e-2)" "unprognostic (5.47e-3)" "unprognostic (1.33e-1)" "unprognostic (2.78e-2)" "unprognostic (4.14e-3)" "unprognostic (1.44e-1)" "unprognostic (2.39e-3)" "unprognostic (3.34e-1)" "unprognostic (3.35e-2)" "unprognostic (1.20e-1)" "unprognostic (6.46e-2)" 1.5 0.1 0.8 0.2 2.6 0.1 2.5 0.4 0.8 1.5 1.8 4.1 0.1 2.9 0.6 5.6 2.6 0.4 40.8 0.8 0.4 0.7 0.1 0.9 0.1 0.8 0.9 2.7 20.2 1.2 1.7 1.6 0.6 1.3 0.4 1.2 7.3 0.7 15.6 1.2 0.8 2.2 0.5 0.1 1.0 0.8 0.8 0.5 1.0 3.8 0.6 1.0 5.5 0.7 0.0 1.6 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.2 0.1 0.1 0.0 0.0 2.5 6.0 5.2 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 1.4 0.0 16.2 0.0 0.0 0.0 0.1 15.0 0.1 0.0 0.6 4.9 9.2 0.0 0.0 0.3 0.5 0.0 0.0 0.4 0.1 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2.6 0.4 0.8 0.8 0.4 0.8 0.9 0.6 0.5 0.8 0.7 0.3 0.0 0.0 0.7 0.2 0.1 0.2 0.4 1.2 1.4 0.8 0.5 151.5 0.0 0.1 0.0 2.1 1.6 0.0 0.7 1.9 0.0 0.8 0.5 1.2 1.5 0.0 0.0 14.8 0.2 0.2 3.3 0.0 0.1 0.0 14.6 1.4 0.0 0.1 0.0 15.4 0.7 2.0 0.0 0.0 0.8 4.4 0.0 0.0 17.8 0.0 0.1 0.0 1.5 0.6 0.0 0.1 13.5 1.0 0.0 2.0 1.5 12.4 2.7 6.6 3.7 5.4 0.5 0.8 3.7 0.0 3.1 0.2 1.7 0.2 0.3 RBM39 "CAPER, CAPERalpha, CC1.3, fSAP59, HCC1, RNPC2" ENSG00000131051 "RNA binding motif protein 39" Q14498 20 35701347-35742312 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001591 Supported Supported "Nucleoplasm,Nuclear speckles,Microtubules,Centriolar satellite" NA NA 19000 "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nuclear speckles" "Microtubules, Centriolar satellite" "HPA001591: AB_1079749" "unprognostic (1.37e-2)" "unprognostic (4.97e-1)" "unprognostic (2.72e-2)" "unprognostic (9.09e-2)" "unprognostic (3.47e-1)" "unprognostic (4.99e-2)" "unprognostic (3.55e-3)" "unprognostic (4.56e-2)" "unprognostic (7.83e-2)" "unprognostic (2.65e-1)" "unprognostic (2.04e-2)" "unprognostic (7.65e-3)" "prognostic unfavorable (2.78e-5)" "unprognostic (1.88e-1)" "unprognostic (2.86e-1)" "unprognostic (2.64e-1)" "unprognostic (2.28e-3)" 70.1 55.8 18.4 37.7 17.6 172.0 44.6 33.5 28.0 57.8 22.2 56.0 35.1 54.5 9.2 62.3 61.4 40.8 57.3 16.5 25.0 52.2 47.7 62.2 42.3 24.2 24.0 71.1 41.2 27.3 50.0 40.9 19.4 50.2 16.9 49.5 53.4 22.3 70.3 51.2 46.9 19.2 16.0 56.4 49.7 34.3 16.9 51.1 54.2 33.1 24.1 50.7 62.1 26.5 98.8 87.6 77.0 78.5 48.8 53.8 78.8 131.0 50.6 59.6 60.2 109.3 78.5 137.5 90.6 38.9 67.9 91.2 122.3 67.9 66.5 94.6 96.7 174.6 80.7 101.2 23.4 158.6 99.9 14.4 97.6 68.9 38.4 63.7 57.8 46.4 195.5 117.6 46.3 72.2 194.5 87.9 103.2 87.5 96.8 104.9 136.2 91.7 41.5 56.2 77.9 63.4 91.1 94.7 78.4 109.3 70.6 94.6 91.4 100.8 92.5 90.5 115.8 71.6 164.3 204.0 64.7 123.2 79.2 250.9 120.4 197.5 104.7 111.1 103.6 131.1 91.5 97.6 111.8 140.5 85.7 82.1 427.7 127.2 102.2 160.9 114.7 95.7 18.4 17.6 33.5 28.0 16.5 25.0 24.2 24.0 19.4 16.0 16.9 26.5 302.0 233.9 280.9 144.3 441.7 616.4 521.0 283.0 284.0 258.5 339.1 295.4 189.2 191.6 267.6 200.5 316.9 375.2 624.9 278.1 189.8 203.8 48.1 359.2 496.0 299.7 295.3 214.2 130.1 186.0 389.6 337.9 254.9 540.8 525.8 304.4 215.3 202.1 199.8 220.4 120.9 331.3 215.7 207.7 469.5 41.9 262.5 335.5 270.3 129.3 274.3 208.7 400.6 136.2 160.5 221.3 254.8 214.4 391.0 453.6 271.8 150.6 248.0 386.5 164.3 504.0 410.2 263.5 228.1 215.8 586.9 561.6 490.8 218.2 282.8 532.1 RGS14 ENSG00000169220 "Regulator of G protein signaling 14" O43566 5 177357924-177372596 "Predicted intracellular proteins" "Cell cycle, Cell division" "GTPase activation, Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 110.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 72.8;Proximal tubular cells: 113.7;Squamous epithelial cells: 95.8;Suprabasal keratinocytes: 115.1" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basal ganglia: 110.4;cerebral cortex: 67.9;hippocampal formation: 56.4" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 112.5;HMC-1: 95.4;NB-4: 44.8;RPMI-8226: 57.9" "Group enriched" "Detected in many" 10 "amygdala: 66.0;basal ganglia: 57.9;cerebral cortex: 46.8;hippocampal formation: 93.6;white matter: 23.8" "Region enhanced" "Detected in many" "basal ganglia: 102.1" "HPA046847, HPA061819" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Intermediate filaments" No No "Cluster 5: Granulocytes - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 44: HDLM-2 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "Vesicles, Plasma membrane, Intermediate filaments" "HPA046847: AB_2679836, HPA061819: " "unprognostic (6.05e-3)" "unprognostic (1.65e-2)" "unprognostic (8.57e-2)" "unprognostic (2.61e-1)" "prognostic unfavorable (6.97e-4)" "unprognostic (7.27e-2)" "prognostic unfavorable (1.84e-6)" "unprognostic (1.95e-2)" "unprognostic (4.34e-2)" "unprognostic (2.04e-3)" "unprognostic (2.71e-1)" "unprognostic (1.28e-1)" "unprognostic (9.95e-2)" "unprognostic (3.17e-2)" "unprognostic (1.66e-1)" "unprognostic (1.17e-2)" "unprognostic (2.78e-2)" 3.5 2.8 16.0 13.9 110.4 22.4 2.9 0.0 67.9 3.1 1.8 3.7 6.3 2.3 0.4 10.0 7.7 4.3 1.3 56.4 4.5 8.5 28.7 5.5 18.1 0.0 0.4 1.1 3.7 1.5 2.4 1.4 0.1 3.5 0.9 0.0 6.2 2.1 2.6 6.1 11.0 1.8 0.1 27.7 4.9 1.9 15.2 16.3 6.1 0.9 6.6 4.1 5.0 3.2 5.4 1.1 2.3 1.4 0.1 0.0 3.7 0.2 0.0 0.5 0.6 3.7 10.4 13.3 7.3 0.4 1.3 10.6 0.2 3.8 0.0 112.5 0.5 20.7 1.0 4.7 0.9 16.3 95.4 1.8 1.1 0.6 0.7 1.4 0.6 14.9 3.5 26.5 0.2 0.4 21.7 44.8 1.7 5.4 2.8 10.2 0.3 57.9 1.5 1.6 0.4 1.9 0.4 0.4 8.8 0.0 3.5 25.2 1.1 0.2 1.9 0.0 9.7 13.9 7.1 5.8 1.6 30.3 2.4 70.6 39.9 148.8 62.4 37.9 63.0 27.7 57.9 57.8 39.8 26.6 47.4 43.1 140.0 23.6 41.2 17.6 60.9 43.9 16.0 110.4 0.0 67.9 56.4 4.5 0.0 0.4 0.1 0.1 15.2 3.2 5.3 6.4 4.4 2.6 27.3 68.8 23.9 15.4 72.8 0.7 8.9 11.8 2.3 37.1 5.6 11.0 2.1 3.9 41.4 4.2 31.3 11.4 0.6 19.5 2.0 6.5 4.8 7.4 4.6 16.7 10.4 5.4 12.2 8.1 24.7 2.8 8.2 64.0 26.1 0.0 1.5 10.0 10.2 17.0 23.3 1.5 2.8 18.2 21.4 6.5 18.1 9.9 48.4 0.5 0.3 12.8 17.2 2.2 18.0 14.1 16.8 113.7 11.7 2.0 0.0 1.6 4.6 0.1 20.3 95.8 115.1 3.3 51.2 1.1 4.4 20.0 RNF169 KIAA1991 ENSG00000166439 "Ring finger protein 169" Q8NCN4 11 74748849-74842413 "Enzymes, Predicted intracellular proteins" "DNA damage, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038505, HPA046138, HPA047952" Uncertain Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Nuclear bodies,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nuclear bodies" "Nucleoli, Nucleoli rim, Cytosol" "HPA038505: , HPA046138: AB_2679553, HPA047952: " "unprognostic (1.71e-1)" "unprognostic (4.18e-2)" "unprognostic (4.34e-2)" "unprognostic (3.72e-2)" "unprognostic (3.86e-2)" "unprognostic (3.25e-2)" "unprognostic (1.74e-1)" "unprognostic (1.35e-1)" "unprognostic (2.68e-1)" "unprognostic (6.47e-2)" "prognostic unfavorable (8.04e-4)" "unprognostic (2.76e-1)" "unprognostic (1.46e-1)" "unprognostic (3.23e-1)" "unprognostic (2.34e-1)" "unprognostic (9.55e-3)" "unprognostic (1.21e-1)" 4.2 2.8 3.8 6.7 6.2 14.4 5.6 6.2 4.4 5.5 5.4 4.4 4.0 7.6 4.2 10.1 5.6 4.8 3.2 4.0 4.4 4.6 5.0 5.9 6.3 5.4 5.0 7.6 4.4 5.6 2.1 4.7 5.4 5.2 5.3 6.1 4.5 4.3 6.8 5.5 4.4 7.6 4.4 7.3 4.6 2.9 4.6 7.7 5.8 5.8 6.7 5.2 5.4 9.2 10.2 7.7 9.1 9.0 5.8 7.7 3.7 7.9 7.4 8.6 7.4 13.0 7.5 18.2 7.9 9.5 5.8 9.6 12.4 9.3 11.2 9.1 8.0 12.6 15.3 5.1 6.6 6.8 10.1 7.1 7.2 9.8 22.1 9.6 14.0 12.2 11.4 14.1 8.7 8.6 11.6 12.0 3.6 12.9 5.0 10.7 21.7 9.9 5.5 10.6 4.1 7.4 10.6 8.0 16.6 7.3 9.9 8.6 9.4 14.2 11.8 9.0 7.1 10.2 5.8 21.1 2.8 7.3 8.4 1.2 0.5 0.4 0.4 0.3 0.3 0.0 0.4 0.2 0.2 0.1 0.3 0.2 1.4 0.3 0.3 0.2 0.3 0.2 3.8 6.2 6.2 4.4 4.0 4.4 5.4 5.0 5.4 4.4 4.6 9.2 18.8 9.6 11.4 51.6 18.4 19.9 30.6 7.1 20.5 58.2 12.6 9.8 3.0 17.2 8.3 3.7 52.1 5.5 24.6 9.8 5.9 10.2 2.8 30.5 26.7 17.2 12.0 18.3 40.8 11.1 6.4 16.0 14.8 30.1 7.0 24.4 10.8 12.3 8.5 37.0 43.2 8.7 2.0 15.6 19.9 3.1 7.5 16.6 10.6 25.3 12.6 22.9 26.8 42.7 68.7 10.1 6.8 10.5 18.5 49.7 6.3 12.1 8.9 33.7 26.3 31.9 18.7 9.4 11.7 16.4 18.6 8.1 22.2 14.0 10.4 42.2 RPF2 "bA397G5.4, BXDC1, FLJ21087" ENSG00000197498 "Ribosome production factor 2 homolog" Q9H7B2 6 110982015-111028263 "Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "U-2197: 234.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035475 Supported Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 18: U-2197 - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "HPA035475: AB_10669861" "unprognostic (2.85e-3)" "unprognostic (2.19e-2)" "unprognostic (6.00e-2)" "unprognostic (2.90e-3)" "unprognostic (4.45e-1)" "prognostic unfavorable (2.04e-4)" "prognostic unfavorable (2.25e-4)" "unprognostic (1.14e-1)" "unprognostic (1.12e-1)" "unprognostic (1.99e-1)" "unprognostic (8.43e-2)" "unprognostic (9.16e-2)" "prognostic unfavorable (2.07e-6)" "unprognostic (2.39e-2)" "unprognostic (2.35e-1)" "unprognostic (1.28e-1)" "unprognostic (1.86e-1)" 16.4 12.2 6.6 9.5 7.4 10.8 14.9 7.3 8.7 12.9 7.2 11.9 6.6 11.2 5.4 15.2 12.5 9.1 15.3 7.0 7.1 15.8 17.2 9.7 10.4 6.9 6.9 13.2 19.9 9.7 8.1 10.2 7.0 11.4 8.8 5.6 9.9 7.1 22.2 13.9 8.1 8.1 6.9 9.3 11.7 13.5 7.1 7.6 13.0 14.0 10.9 15.3 12.5 7.9 23.3 16.6 12.7 50.5 26.4 34.7 32.6 32.5 23.6 32.3 32.6 39.2 18.5 50.2 29.4 22.8 38.8 27.0 51.5 37.6 84.2 19.4 38.7 29.5 14.2 27.4 35.9 45.9 16.6 26.5 31.4 46.5 83.5 20.3 24.9 22.1 99.0 29.9 52.2 23.4 39.2 45.5 45.2 37.7 20.2 40.2 22.4 43.6 37.4 22.9 20.3 28.7 14.1 23.7 61.3 16.8 18.8 47.3 17.5 24.7 21.2 234.1 81.4 13.4 22.0 65.0 36.4 60.8 55.2 0.2 4.4 0.7 4.1 5.5 8.5 6.6 6.1 5.0 5.8 5.7 6.8 7.0 0.3 8.8 3.5 5.8 5.0 4.0 6.6 7.4 7.3 8.7 7.0 7.1 6.9 6.9 7.0 6.9 7.1 7.9 40.0 19.2 26.9 6.5 25.0 78.4 119.6 90.1 35.9 14.1 33.6 52.3 71.9 47.1 67.6 18.4 0.0 44.9 18.0 15.8 68.4 48.2 105.7 49.8 57.6 35.2 11.4 26.1 15.7 47.4 53.8 50.0 17.3 60.9 46.2 18.9 23.6 83.6 56.0 18.5 14.0 30.3 36.7 27.7 19.5 32.1 34.5 28.2 37.4 5.6 21.8 21.0 19.6 9.0 13.5 42.2 18.7 27.1 18.8 80.4 15.2 87.2 55.0 8.9 13.1 61.7 49.9 76.8 28.4 33.0 66.2 34.6 22.9 29.8 44.0 70.2 RPP30 TSG15 ENSG00000148688 "Ribonuclease P/MRP subunit p30" P78346 10 90871952-90908553 "Enzymes, Plasma proteins, Predicted intracellular proteins" "rRNA processing, tRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037578 Approved Approved "Nucleoplasm,Nucleoli,Microtubule ends,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli" "Microtubule ends, Cytosol" "HPA037578: AB_10696939" "unprognostic (1.55e-1)" "unprognostic (1.77e-3)" "unprognostic (2.35e-1)" "unprognostic (4.08e-1)" "unprognostic (5.64e-2)" "unprognostic (3.05e-2)" "unprognostic (3.80e-3)" "unprognostic (1.27e-1)" "unprognostic (2.73e-1)" "unprognostic (1.03e-1)" "unprognostic (2.27e-2)" "unprognostic (2.65e-1)" "prognostic unfavorable (1.01e-6)" "unprognostic (1.98e-1)" "unprognostic (9.84e-3)" "unprognostic (3.43e-2)" "unprognostic (2.10e-2)" 19.2 13.9 7.8 12.9 8.8 25.9 17.3 8.2 10.6 14.1 7.3 15.3 9.3 15.8 14.1 18.0 14.9 12.7 22.6 8.8 8.4 16.3 15.1 13.1 21.0 7.1 7.3 18.1 11.0 23.0 8.0 18.5 7.6 12.1 15.1 13.2 14.5 12.2 31.1 17.9 12.4 16.4 8.3 15.0 14.3 28.6 7.7 21.7 12.2 22.2 22.4 17.0 14.2 10.6 82.2 53.2 55.0 66.5 34.4 37.6 19.4 57.0 51.1 93.3 98.3 90.6 64.1 48.1 42.6 36.4 60.9 56.0 73.9 50.5 95.3 77.2 51.3 32.7 31.1 73.0 33.0 66.7 39.1 30.9 32.4 70.5 79.1 39.6 54.1 43.5 65.7 42.6 62.6 50.8 77.4 89.8 33.9 46.4 59.8 42.9 46.7 50.4 35.6 38.2 29.9 29.9 33.1 23.8 68.2 50.0 64.8 41.3 31.2 46.3 46.3 26.5 119.6 28.7 79.4 104.4 57.9 35.4 36.4 9.2 30.0 27.1 25.2 30.7 27.5 31.7 28.7 28.0 35.1 28.1 24.6 27.0 3.5 25.4 26.2 32.8 33.0 27.6 7.8 8.8 8.2 10.6 8.8 8.4 7.1 7.3 7.6 8.3 7.7 10.6 31.4 32.1 16.9 14.0 28.7 34.4 27.5 51.8 23.9 19.2 16.7 28.2 45.7 27.1 31.4 14.7 18.8 60.6 33.7 9.4 31.3 41.9 95.9 18.9 26.1 25.2 19.8 38.5 18.0 35.0 68.1 28.0 13.3 17.9 23.5 33.3 21.4 14.3 58.1 16.8 19.4 21.0 30.5 23.9 29.3 49.9 28.9 24.7 23.2 11.2 32.2 23.3 15.5 17.6 19.6 31.3 12.5 29.3 20.6 18.8 12.5 36.5 21.6 24.3 39.5 30.1 36.9 77.9 54.2 20.2 34.0 33.8 23.7 28.6 17.6 27.6 RPUSD1 "C16orf40, MGC19600, RLUCL" ENSG00000007376 "RNA pseudouridine synthase domain containing 1" Q9UJJ7 16 784974-788397 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041144, HPA041938" Approved Approved "Nucleoplasm,Golgi apparatus,Cell Junctions,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 56: Bipolar cells - Visual perception" "Golgi apparatus" "Nucleoplasm, Cell Junctions, Cytosol" "HPA041144: AB_10794265, HPA041938: AB_10795601" "unprognostic (1.51e-2)" "unprognostic (1.26e-3)" "unprognostic (2.03e-1)" "unprognostic (4.01e-1)" "unprognostic (2.99e-1)" "unprognostic (9.05e-3)" "unprognostic (1.07e-3)" "unprognostic (3.45e-2)" "unprognostic (1.08e-1)" "unprognostic (3.31e-1)" "unprognostic (2.04e-1)" "unprognostic (1.23e-1)" "unprognostic (6.25e-2)" "unprognostic (8.07e-3)" "unprognostic (5.44e-2)" "unprognostic (2.95e-1)" "unprognostic (1.41e-1)" 11.8 12.9 12.3 9.7 11.9 13.5 12.0 11.2 21.1 11.0 6.8 14.9 9.8 13.1 3.1 18.7 10.6 4.7 12.0 12.5 10.0 13.0 15.3 9.5 11.3 12.9 10.7 9.2 16.1 4.5 11.2 4.2 10.9 14.6 2.5 2.2 15.2 5.1 11.2 18.1 15.6 3.6 9.7 21.9 17.0 7.2 12.4 8.3 11.0 3.1 5.3 13.1 11.8 11.6 28.2 32.5 7.8 35.7 6.8 7.9 36.2 22.9 13.0 29.4 21.3 76.4 25.8 38.9 24.3 11.1 20.6 47.2 18.1 23.1 5.3 35.7 74.0 19.2 52.1 28.0 10.9 35.8 31.1 11.7 21.9 25.4 6.7 8.7 20.4 22.6 45.7 17.1 10.2 89.2 44.8 37.4 40.0 13.0 55.4 79.0 21.0 80.5 10.9 17.0 40.8 29.4 26.4 42.7 26.1 4.6 22.0 43.9 23.3 29.1 37.9 30.9 33.6 27.2 29.6 45.7 14.1 27.8 24.5 16.5 14.8 13.7 12.7 13.7 12.6 10.2 10.7 14.1 17.0 12.0 10.7 11.1 9.2 13.4 13.6 15.8 14.8 13.1 12.3 11.9 11.2 21.1 12.5 10.0 12.9 10.7 10.9 9.7 12.4 11.6 9.4 3.2 3.3 3.6 12.9 15.9 3.5 13.2 10.8 42.0 12.8 13.3 4.4 5.7 5.2 9.2 2.1 20.5 13.7 23.0 7.9 19.5 0.4 4.7 7.1 8.1 13.2 6.3 6.0 26.9 25.7 6.8 17.9 8.2 0.0 10.9 9.3 5.1 19.6 1.7 4.2 11.5 10.2 5.7 7.0 1.8 6.8 9.0 14.2 1.9 19.2 11.1 23.7 1.5 3.5 29.9 16.6 6.4 19.5 6.3 21.1 10.2 3.4 3.8 13.1 3.6 9.4 3.6 11.4 11.5 16.8 14.6 11.9 13.3 20.7 5.0 RRP15 "CGI-115, KIAA0507" ENSG00000067533 "Ribosomal RNA processing 15 homolog" Q9Y3B9 1 218285293-218337983 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024639 Approved Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome,Mitochondria" Yes No "Cluster 30: Non-specific - Translation" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli rim, Mitotic chromosome" "Nucleoplasm, Mitochondria" "HPA024639: AB_1844368" "unprognostic (2.68e-2)" "unprognostic (4.94e-2)" "unprognostic (2.04e-1)" "unprognostic (1.22e-1)" "unprognostic (5.19e-2)" "unprognostic (1.33e-2)" "prognostic unfavorable (4.26e-5)" "unprognostic (7.87e-2)" "unprognostic (1.07e-1)" "unprognostic (2.18e-1)" "unprognostic (3.65e-3)" "unprognostic (2.54e-1)" "unprognostic (2.76e-3)" "unprognostic (1.52e-1)" "unprognostic (5.77e-1)" "unprognostic (1.11e-2)" "unprognostic (3.23e-2)" 4.0 2.6 1.7 3.3 1.7 4.1 4.7 2.5 2.4 3.0 1.4 3.0 2.1 3.7 2.7 3.0 2.9 1.9 4.9 1.8 1.9 3.4 3.5 2.8 3.7 1.4 2.0 3.8 2.9 4.5 1.8 3.6 1.6 3.1 2.9 2.2 2.6 2.4 9.6 3.5 2.4 3.4 1.5 2.9 2.6 2.4 1.8 2.6 3.5 7.7 3.5 3.9 2.8 1.9 9.8 7.2 7.9 5.7 5.6 7.8 6.7 9.8 7.3 10.0 7.2 14.1 8.8 14.0 13.1 7.6 6.7 8.7 13.5 13.0 16.6 5.7 10.1 10.9 6.6 7.8 11.6 17.0 5.6 5.4 7.8 13.1 17.4 4.4 6.6 6.5 22.7 4.4 11.4 8.9 11.3 8.3 15.7 7.8 14.8 7.8 4.9 13.8 8.0 8.9 9.0 13.1 8.3 15.3 15.0 9.3 11.0 12.1 9.3 8.0 7.6 14.3 18.3 5.4 8.9 14.4 9.1 8.1 13.1 0.3 0.8 0.1 1.6 1.3 2.3 2.4 2.0 1.4 1.2 2.3 2.6 2.6 0.2 1.6 1.1 1.7 1.3 0.7 1.7 1.7 2.5 2.4 1.8 1.9 1.4 2.0 1.6 1.5 1.8 1.9 33.7 32.1 28.1 7.5 36.0 65.3 33.6 28.7 24.5 31.1 32.6 31.0 68.4 22.8 25.0 36.8 10.4 38.1 32.7 13.5 27.4 39.7 17.0 22.6 47.3 27.9 12.1 41.0 18.4 52.2 59.1 32.2 19.9 28.5 31.0 18.6 21.8 44.2 33.6 26.9 16.1 20.8 6.1 17.3 18.5 4.6 37.6 17.4 21.4 7.5 20.8 21.2 24.7 7.5 9.0 36.8 9.0 24.8 13.0 34.9 5.2 37.2 11.7 23.6 26.3 72.1 33.0 59.7 69.1 24.3 47.6 18.1 26.4 20.4 32.1 23.0 RRP1B "KIAA0179, Nnp1, PPP1R136, RRP1" ENSG00000160208 "Ribosomal RNA processing 1B" Q14684 21 43659560-43696079 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, mRNA processing, mRNA splicing, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 131.3;Early spermatids: 213.2;Late spermatids: 222.8;Rod photoreceptor cells: 143.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA017893, HPA020324" Supported Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 32: T-cells - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoli, Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA017893: AB_1852274, HPA020324: AB_1852276" "unprognostic (1.03e-1)" "unprognostic (1.37e-2)" "unprognostic (4.03e-1)" "unprognostic (1.32e-3)" "unprognostic (1.24e-1)" "unprognostic (1.92e-2)" "unprognostic (2.03e-2)" "unprognostic (7.19e-2)" "unprognostic (1.98e-2)" "unprognostic (5.55e-3)" "unprognostic (1.08e-2)" "unprognostic (1.01e-1)" "prognostic unfavorable (2.95e-9)" "unprognostic (1.45e-1)" "unprognostic (1.10e-1)" "unprognostic (1.05e-2)" "unprognostic (4.24e-2)" 8.8 5.9 7.9 12.2 8.9 6.2 9.1 7.0 7.8 7.2 5.9 7.2 6.7 9.1 5.5 8.6 9.1 6.1 4.9 7.4 7.2 4.9 8.7 6.7 17.4 7.8 7.9 13.1 10.2 7.2 4.3 5.8 7.2 7.5 7.3 28.4 10.2 6.8 12.1 8.8 6.4 8.8 7.4 11.0 7.8 12.0 7.8 16.1 6.5 8.8 14.8 9.8 6.5 8.6 52.5 30.4 31.8 48.1 20.2 21.5 26.0 27.0 19.3 29.3 24.0 69.4 22.2 101.9 17.2 21.5 33.9 22.8 78.9 46.5 34.6 34.6 62.8 60.3 34.8 43.9 27.9 95.0 22.9 22.4 29.2 35.1 40.3 18.1 33.1 43.2 96.0 29.1 26.1 27.4 76.1 28.9 108.4 33.7 33.4 98.7 32.1 71.2 21.2 24.8 62.7 33.6 50.6 36.9 37.9 11.7 24.2 29.4 29.7 9.0 28.3 24.0 49.8 39.1 53.8 119.3 28.5 100.7 30.1 2.0 2.5 0.7 6.2 2.5 7.3 5.6 7.9 7.5 3.0 4.3 7.2 8.6 0.1 5.8 2.2 2.4 6.6 5.5 7.9 8.9 7.0 7.8 7.4 7.2 7.8 7.9 7.2 7.4 7.8 8.6 15.5 32.1 16.4 8.8 32.7 22.8 17.7 15.0 28.5 30.3 13.8 11.0 13.4 17.2 21.0 5.5 131.3 8.6 27.1 5.7 1.9 17.0 213.2 10.5 28.8 19.1 5.4 23.7 19.0 15.6 17.0 18.9 14.8 10.8 36.0 25.5 12.8 18.4 18.7 25.2 20.0 9.2 6.1 13.9 12.7 222.8 22.4 13.4 8.8 21.5 17.0 17.9 35.0 18.6 22.2 20.9 3.7 26.7 48.5 23.6 6.8 9.9 16.7 143.5 0.0 29.9 18.1 26.3 33.6 32.0 31.7 4.4 35.7 32.6 16.5 17.4 RTN4RL1 "DKFZp547J144, NgR3, NGRH2" ENSG00000185924 "Reticulon 4 receptor like 1" Q86UN2 17 1934677-2025334 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 20.6;Cone photoreceptor cells: 37.5;Excitatory neurons: 43.5;Horizontal cells: 33.7;Inhibitory neurons: 18.6" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "hippocampal formation: 12.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 10.9;HaCaT: 10.8;hTCEpi: 10.1;T-47d: 13.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044428 Uncertain Approved "Nucleoplasm,Plasma membrane,Actin filaments,Midbody" "Intracellular and membrane" Yes NA 35000 "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Actin filaments" "Nucleoplasm, Plasma membrane, Midbody" "HPA044428: AB_10963229" "unprognostic (5.23e-1)" "unprognostic (3.52e-2)" "unprognostic (2.06e-1)" "unprognostic (2.12e-1)" "unprognostic (2.93e-2)" "unprognostic (7.25e-2)" "unprognostic (2.61e-3)" "unprognostic (1.17e-1)" "unprognostic (8.97e-3)" "unprognostic (6.21e-2)" "unprognostic (2.55e-3)" "unprognostic (6.32e-3)" "prognostic unfavorable (7.69e-4)" "unprognostic (3.86e-2)" "unprognostic (1.05e-1)" "unprognostic (7.01e-2)" "unprognostic (3.15e-2)" 4.0 3.1 4.6 0.3 4.0 0.0 6.4 0.0 9.2 2.1 0.0 0.4 0.1 0.8 0.2 1.3 1.5 0.6 2.3 12.3 0.3 1.6 2.6 1.6 0.1 0.0 0.5 0.9 1.8 1.3 5.9 0.3 0.0 3.4 0.1 8.5 4.4 2.0 1.8 9.6 0.5 0.3 0.0 1.1 0.7 0.8 1.9 0.2 1.4 0.4 0.1 1.5 2.2 0.0 1.4 1.6 1.8 2.5 2.0 0.3 0.0 0.1 1.1 0.3 0.0 0.0 0.0 0.0 0.1 10.9 0.2 10.8 4.6 0.1 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 10.1 0.0 3.6 0.0 0.0 2.5 0.1 0.0 0.1 0.5 0.0 0.0 0.3 0.0 0.3 0.8 0.3 1.2 0.0 0.0 2.2 0.0 0.3 0.8 1.7 0.2 13.3 0.1 0.0 0.0 0.2 0.5 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 4.0 0.0 9.2 12.3 0.3 0.0 0.5 0.0 0.0 1.9 0.0 1.0 0.0 2.2 1.6 0.1 2.7 0.2 0.0 1.8 20.6 5.4 4.3 3.0 1.5 1.3 3.7 37.5 0.0 0.1 0.0 0.0 0.6 0.3 0.0 0.0 0.7 0.0 0.0 43.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 6.1 3.3 1.8 33.7 18.6 0.0 0.0 0.3 0.4 1.1 0.0 0.1 3.6 7.5 0.0 1.8 0.0 8.5 1.7 0.1 0.0 0.0 0.1 0.9 0.0 0.1 1.5 10.0 0.0 0.0 0.6 0.0 0.2 0.5 2.8 0.0 0.2 0.0 0.0 0.3 RUSF1 "C16orf58, FLJ13868" ENSG00000140688 "RUS family member 1" Q96GQ5 16 31489471-31509309 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 5.8;Cytotrophoblasts: 22.3;Extravillous trophoblasts: 21.0;Hofbauer cells: 14.8;Syncytiotrophoblasts: 22.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024406 Uncertain Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" "Nucleoli, Golgi apparatus, Vesicles" "Nucleoplasm, Cytosol" "HPA024406: AB_1845580" "unprognostic (1.46e-2)" "unprognostic (2.52e-2)" "unprognostic (2.25e-2)" "unprognostic (4.22e-1)" "unprognostic (6.21e-2)" "unprognostic (3.05e-2)" "unprognostic (2.44e-1)" "unprognostic (1.01e-1)" "unprognostic (1.13e-1)" "unprognostic (9.89e-2)" "unprognostic (3.20e-1)" "unprognostic (1.58e-1)" "unprognostic (6.34e-3)" "unprognostic (1.14e-1)" "unprognostic (1.22e-1)" "unprognostic (5.69e-2)" "unprognostic (2.24e-2)" 27.1 31.8 19.6 20.0 18.9 21.5 28.8 12.0 21.3 45.4 14.2 29.6 31.3 43.2 20.7 26.5 38.2 23.0 28.5 19.9 19.7 29.5 57.9 25.0 19.8 17.0 16.0 49.6 56.8 46.2 48.4 25.7 18.5 39.1 19.1 22.4 64.8 34.2 9.4 26.9 30.3 25.6 13.8 22.3 39.5 21.4 17.0 18.0 42.0 9.8 15.6 31.8 31.4 17.0 28.6 37.2 22.7 39.7 51.7 34.3 42.3 33.4 56.6 25.5 30.2 11.3 49.1 24.5 69.4 49.8 32.9 39.0 22.9 31.0 11.8 35.8 23.0 24.8 20.6 28.8 74.8 29.4 28.6 41.7 33.1 33.7 68.5 50.2 24.9 38.4 37.3 40.9 25.3 53.9 13.7 19.8 17.8 41.8 24.1 31.1 34.2 74.8 29.3 17.6 24.8 38.2 25.2 65.3 52.8 21.5 56.6 42.9 22.0 44.3 24.7 28.7 22.1 59.0 37.0 18.8 56.7 44.7 62.5 3.1 5.7 7.6 7.8 8.4 7.2 6.7 8.2 7.8 9.7 6.3 7.9 7.0 0.9 9.4 8.1 8.9 9.4 7.2 19.6 18.9 12.0 21.3 19.9 19.7 17.0 16.0 18.5 13.8 17.0 17.0 5.8 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 22.3 2.6 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 21.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 22.3 0.4 0.0 0.0 0.0 S100A13 ENSG00000189171 "S100 calcium binding protein A13" Q99584 1 153618787-153631360 "Predicted intracellular proteins, Predicted secreted proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Theca cells: 3084.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 28.3" "Group enriched" "Detected in all" 5 "dendritic cells: 11.9;NK-cells: 28.3" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 811.3;SuSa: 896.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019592, CAB025494" Approved Approved "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" "Secreted in other tissues" NA NA 36000 "Cluster 48: NK-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 52: Non-specific - Transcription" "Plasma membrane, Cytosol" "Nucleoplasm, Nucleoli" "CAB025494: , HPA019592: AB_10601499" "unprognostic (1.50e-2)" "unprognostic (9.09e-2)" "unprognostic (2.08e-2)" "unprognostic (1.45e-1)" "unprognostic (7.77e-2)" "unprognostic (9.72e-3)" "unprognostic (1.75e-3)" "unprognostic (9.93e-2)" "unprognostic (6.48e-2)" "unprognostic (1.67e-1)" "unprognostic (1.21e-2)" "unprognostic (4.83e-3)" "prognostic unfavorable (1.97e-4)" "unprognostic (3.43e-2)" "unprognostic (8.10e-2)" "unprognostic (1.82e-3)" "unprognostic (1.72e-2)" 275.3 137.3 237.4 47.7 247.3 4.4 222.4 241.0 347.5 133.7 214.6 198.9 30.6 111.8 72.1 91.7 129.8 103.9 310.1 233.1 240.8 262.2 66.2 138.0 48.8 252.9 245.5 138.2 75.7 317.4 73.9 70.1 249.4 100.9 59.8 25.8 156.1 64.6 250.6 114.0 116.5 68.9 245.8 111.7 94.4 41.2 251.6 21.2 318.7 220.6 49.6 121.2 122.7 258.6 188.7 153.7 174.5 111.4 150.7 437.5 62.7 254.7 400.0 150.6 172.2 150.4 203.7 4.9 471.6 435.5 22.3 174.7 73.5 158.7 132.7 0.8 68.1 12.0 178.0 129.6 99.8 5.9 39.2 355.3 59.4 135.3 145.0 441.9 346.5 1.3 61.4 0.3 475.2 663.4 0.4 3.4 141.0 161.1 460.2 30.0 180.4 1.4 811.3 141.9 53.4 2.0 544.7 277.2 576.7 896.9 226.4 6.8 495.0 103.3 57.9 139.5 312.0 2.0 5.3 9.3 185.5 3.2 62.1 4.1 2.0 0.2 0.4 0.9 0.9 4.1 0.4 0.3 7.0 2.0 0.6 0.5 0.3 28.3 1.4 11.9 1.4 1.1 237.4 247.3 241.0 347.5 233.1 240.8 252.9 245.5 249.4 245.8 251.6 258.6 331.0 28.9 106.1 29.7 9.3 110.5 177.4 105.0 103.0 2.1 311.2 345.6 141.9 164.5 104.0 465.3 0.0 132.4 15.3 148.7 248.4 323.3 8.4 399.3 449.1 251.9 124.7 17.3 1.2 323.6 202.1 450.0 58.6 573.8 23.5 185.5 372.3 51.8 162.3 0.0 0.5 167.5 61.1 31.7 107.7 36.3 771.7 37.1 238.3 13.1 14.8 308.1 1.0 0.0 8.8 488.4 164.7 314.1 6.3 240.0 128.7 521.7 77.1 6.9 0.0 234.2 132.5 12.8 23.4 80.3 75.7 74.7 20.5 3084.7 100.6 244.3 S100A2 "CAN19, S100L" ENSG00000196754 "S100 calcium binding protein A2" P29034 1 153561108-153567890 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 3574.5;kidney: 1380.0;urinary bladder: 1097.4" "Group enriched" "Detected in many" 5 "Basal keratinocytes: 11464.4;Basal prostatic cells: 4796.7;Basal respiratory cells: 10600.9;Basal squamous epithelial cells: 4741.9;Club cells: 3331.1;Prostatic glandular cells: 9446.4;Squamous epithelial cells: 9013.7;Suprabasal keratinocytes: 3626.5;Urothelial cells: 5382.7" "Cancer enhanced" "Detected in all" "cervical cancer: 848.8;head and neck cancer: 1229.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 10.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 10.1" "Group enriched" "Detected in many" 5 "HBEC3-KT: 21286.9;RT4: 8382.8" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002600, CAB047340, HPA062451" Enhanced Approved "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" NA NA 27000 "Cluster 10: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Cytosol" "Nucleoli, Plasma membrane" "CAB002600: , CAB047340: , HPA062451: AB_2684767" "unprognostic (8.47e-3)" "unprognostic (5.54e-2)" "unprognostic (1.57e-2)" "unprognostic (1.42e-3)" "unprognostic (1.98e-1)" "unprognostic (3.20e-1)" "unprognostic (4.21e-4)" "unprognostic (9.00e-2)" "unprognostic (1.64e-1)" "unprognostic (1.23e-2)" "prognostic unfavorable (2.04e-4)" "unprognostic (3.52e-2)" "unprognostic (8.91e-2)" "unprognostic (1.35e-1)" "unprognostic (2.70e-1)" "unprognostic (1.39e-1)" "unprognostic (2.68e-1)" 4.0 2.1 2.5 4.1 2.7 1.0 17.3 2.4 3.6 279.9 2.0 3.1 0.8 2.5 16.1 3574.5 5.6 1.8 3.9 2.3 3.2 1380.0 1.7 12.0 0.5 4.1 3.0 1.9 2.1 0.1 5.4 0.8 3.0 48.1 1.6 0.4 377.1 16.9 3.3 429.6 1.6 1.9 3.0 1.5 3.6 2.8 3.4 6.3 11.9 1.4 416.1 1097.4 747.3 3.5 827.0 9.3 1.1 0.9 10.8 4.2 1.2 10.4 11.5 9.0 7.8 2.1 26.8 1.2 418.3 17.8 18.3 2001.4 1.3 21286.9 9.9 5.4 3.7 3.8 56.2 5.0 4.5 0.7 1.9 8.8 2777.8 24.1 3135.5 21.7 13.2 0.0 0.8 1.5 47.7 3.4 0.2 0.2 2.2 22.3 155.4 1.3 497.9 2.1 502.4 8382.8 16.5 0.5 34.9 5.8 9.0 5.9 3.2 5.7 6.0 12.5 692.6 92.4 280.6 1.9 2.4 4.7 26.5 1.8 24.2 10.1 0.4 0.0 2.3 0.0 1.4 0.4 1.6 1.3 0.3 0.0 0.4 0.3 4.3 0.0 0.5 2.2 1.6 0.7 2.5 2.7 2.4 3.6 2.3 3.2 4.1 3.0 3.0 3.0 3.4 3.5 1.4 9.6 17.3 2.6 1.0 11464.4 4796.7 10600.9 4741.9 0.0 22.2 35.4 2.9 1.5 3331.1 218.8 0.0 0.7 0.8 3.2 1226.7 24.8 4.5 16.3 2.5 108.2 1.8 3.0 0.1 27.6 1.0 130.8 1.5 24.5 17.1 1.2 0.4 0.1 1.8 0.0 0.0 1.6 789.4 0.8 676.4 8.1 0.6 18.0 759.5 0.0 5.3 1.1 0.0 2.0 0.1 668.7 2.5 0.7 25.9 9446.4 0.8 11.8 560.8 0.1 0.0 5.5 207.0 0.6 3.0 9013.7 3626.5 0.3 37.8 8.9 2.0 5382.7 SALL1 "Hsal1, TBS, ZNF794" ENSG00000103449 "Spalt like transcription factor 1" Q9NSC2 16 51135975-51151367 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" Deafness "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.0;kidney: 36.4;liver: 36.5" "Cell type enhanced" "Detected in some" "Astrocytes: 15.3;Cone photoreceptor cells: 25.0;Endometrial stromal cells: 17.5;Glandular and luminal cells: 14.3;Hepatocytes: 30.1;Microglial cells: 26.2;Oligodendrocytes: 47.6;Proximal tubular cells: 20.3" "Cancer enhanced" "Detected in many" "glioma: 19.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 29.5;BJ hTERT+: 25.3;NTERA-2: 48.0;RPTEC TERT1: 40.4;U-87 MG: 46.2" "Region enhanced" "Detected in all" "olfactory bulb: 52.6" "Low region specificity" "Detected in all" "HPA049829, HPA074673" Enhanced Approved "Nucleoplasm,Nucleoli,Nuclear speckles,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 21: Non-specific - Transcription" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nucleoli, Nuclear speckles, Cytosol" "HPA049829: AB_2680902, HPA074673: " "unprognostic (9.91e-2)" "unprognostic (9.42e-2)" "unprognostic (1.82e-6)" "prognostic favorable (1.28e-4)" "unprognostic (2.55e-1)" "unprognostic (1.17e-1)" "unprognostic (1.96e-2)" "unprognostic (4.41e-3)" "unprognostic (1.71e-2)" "unprognostic (2.88e-1)" "unprognostic (1.48e-1)" "unprognostic (3.96e-1)" "prognostic favorable (1.91e-7)" "unprognostic (1.86e-1)" "unprognostic (2.14e-1)" "unprognostic (3.03e-2)" "unprognostic (1.76e-1)" 0.3 0.0 18.0 0.6 29.2 0.1 0.3 29.7 21.3 19.6 2.1 2.6 1.0 17.4 0.0 0.3 11.0 0.4 0.8 17.9 21.7 36.4 36.5 0.0 0.0 41.0 32.2 4.5 1.0 6.5 6.5 3.9 36.6 0.8 2.6 4.6 0.2 1.6 0.0 0.2 1.3 8.4 31.1 0.0 2.5 1.7 26.6 0.1 23.7 0.2 0.0 2.8 7.2 40.2 0.0 1.7 29.5 0.2 0.8 0.6 0.0 10.0 25.3 0.6 1.4 0.0 0.0 0.0 11.2 14.1 8.8 0.0 18.6 0.0 0.9 0.0 11.3 0.0 0.0 18.5 0.7 0.0 8.1 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 48.0 0.0 0.0 3.8 1.9 0.0 40.4 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 46.2 0.0 10.0 0.2 0.6 0.5 0.1 0.4 0.1 0.2 0.2 0.1 0.4 0.2 0.1 0.1 0.3 0.0 0.3 0.4 0.2 0.3 18.0 29.2 29.7 21.3 17.9 21.7 41.0 32.2 36.6 31.1 26.6 40.2 0.0 0.0 0.0 15.3 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.1 1.4 10.0 0.0 9.2 25.0 0.0 0.0 0.0 11.7 0.5 0.7 8.9 17.5 0.9 0.0 2.7 0.2 0.0 0.0 1.6 0.0 14.3 0.0 0.0 0.7 30.1 0.1 0.0 8.2 0.0 0.0 1.0 0.3 0.1 0.0 0.4 0.0 26.2 0.0 0.5 0.0 5.0 47.6 0.0 0.0 0.0 0.0 0.0 0.0 20.3 0.0 1.0 0.0 0.0 0.5 0.2 2.3 0.0 0.1 0.0 0.3 0.6 0.0 0.1 SC5D SC5DL ENSG00000109929 Sterol-C5-desaturase O75845 11 121292681-121313410 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 393.6" "Cell type enhanced" "Detected in all" "Hepatic stellate cells: 141.0;Hepatocytes: 307.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066283, HPA070248" Enhanced Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane,Cytosol" No No "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 15: Hepatocytes - Hemostasis" "Nucleoplasm, Endoplasmic reticulum" "Plasma membrane, Cytosol" "HPA066283: AB_2685648, HPA070248: AB_2686240" "unprognostic (4.78e-2)" "unprognostic (7.29e-2)" "unprognostic (2.26e-2)" "unprognostic (2.36e-1)" "unprognostic (3.98e-2)" "prognostic unfavorable (3.30e-4)" "unprognostic (2.79e-2)" "unprognostic (7.96e-2)" "prognostic unfavorable (3.98e-4)" "unprognostic (4.03e-2)" "unprognostic (3.18e-2)" "unprognostic (1.01e-1)" "prognostic favorable (1.07e-7)" "unprognostic (4.29e-2)" "unprognostic (2.51e-1)" "unprognostic (2.29e-1)" "unprognostic (1.98e-1)" 28.6 35.3 18.4 12.6 20.4 5.7 56.6 37.1 29.3 20.7 17.6 23.2 48.2 15.1 73.2 39.6 16.5 18.2 22.0 19.9 29.9 49.1 393.6 24.6 13.5 42.9 28.0 16.9 21.5 48.6 15.6 14.7 39.1 101.4 19.9 29.5 22.4 56.6 7.7 13.8 24.7 16.2 32.2 8.8 21.7 24.3 24.6 13.5 23.9 13.0 19.5 21.5 27.1 36.5 26.5 14.3 184.8 39.5 72.1 59.9 27.8 27.8 53.5 18.2 32.4 83.1 95.9 25.4 89.0 32.3 156.6 100.8 59.2 70.9 18.1 12.5 80.0 34.6 73.4 64.4 57.9 24.8 12.5 51.0 57.4 60.4 60.2 15.6 29.8 22.8 25.0 34.6 89.0 27.4 9.4 29.2 59.8 74.4 39.7 13.2 51.0 21.6 133.6 116.5 51.1 28.8 73.4 14.6 38.0 125.4 62.2 38.6 58.3 19.0 29.7 32.5 14.0 6.4 11.2 33.3 7.0 49.5 33.5 7.8 3.7 1.0 3.5 4.9 5.9 4.4 4.7 4.2 6.5 4.1 6.8 6.7 0.3 5.3 3.6 7.7 5.5 2.6 18.4 20.4 37.1 29.3 19.9 29.9 42.9 28.0 39.1 32.2 24.6 36.5 10.4 19.2 31.9 23.8 62.6 9.7 49.9 48.9 14.8 26.8 33.7 12.4 20.8 18.6 40.8 20.2 31.3 15.9 47.5 26.4 5.9 24.1 3.0 11.5 8.8 15.7 14.4 18.1 29.6 28.9 16.7 16.3 18.3 19.6 17.7 11.1 141.0 307.1 21.0 23.5 29.4 15.3 59.0 22.1 17.0 1.3 19.3 17.6 19.6 20.6 15.6 38.7 13.4 27.6 34.0 19.3 18.8 17.0 20.9 50.1 24.1 15.8 18.7 28.3 13.1 12.9 14.7 6.7 12.7 36.2 15.5 18.6 56.5 42.8 13.3 54.4 SCHIP1 SCHIP-1 ENSG00000151967 "Schwannomin interacting protein 1" P0DPB3 3 159839861-159897360 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 81.0;choroid plexus: 28.9;heart muscle: 80.4;skeletal muscle: 101.3;tongue: 92.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 14.2;Horizontal cells: 15.2;Skeletal myocytes: 7.0" "Cancer enriched" "Detected in single" 7 "glioma: 2.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 6.9" "Group enriched" "Detected in many" 46 "dendritic cells: 6.9;granulocytes: 2.1" "Cell line enhanced" "Detected in many" "AF22: 27.0;AN3-CA: 49.2;HUVEC TERT2: 58.3;NTERA-2: 29.8;SH-SY5Y: 167.0" "HPA003243, HPA069824" Uncertain Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane, Cell Junctions, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA003243: AB_1079877, HPA069824: AB_2732142" "unprognostic (1.07e-1)" "unprognostic (3.27e-2)" "unprognostic (1.37e-2)" "unprognostic (2.36e-5)" "prognostic favorable (2.80e-4)" "unprognostic (6.25e-2)" "unprognostic (4.56e-3)" "unprognostic (1.11e-1)" "unprognostic (7.81e-2)" "unprognostic (1.38e-1)" "unprognostic (6.45e-3)" "unprognostic (4.67e-2)" "unprognostic (2.12e-1)" "unprognostic (4.66e-4)" "unprognostic (2.30e-1)" "unprognostic (4.52e-2)" "unprognostic (4.96e-1)" 6.1 2.9 46.5 0.2 56.3 0.8 1.2 52.6 55.0 2.5 28.9 11.1 1.0 3.9 0.7 3.4 2.3 1.9 80.4 50.0 48.7 2.5 0.7 2.9 0.5 51.0 48.2 0.5 0.4 0.2 11.8 10.9 52.6 5.6 1.1 3.6 1.9 1.4 101.3 0.4 3.6 5.4 55.6 4.8 4.6 1.9 46.9 0.8 0.8 92.8 0.2 0.7 1.2 81.0 0.1 0.0 27.0 49.2 0.0 0.2 0.0 0.2 0.1 0.1 1.1 0.0 0.0 0.0 1.7 0.0 1.3 0.0 0.0 2.4 0.0 1.4 0.0 0.0 0.0 0.0 1.3 0.0 0.0 2.7 1.1 0.3 11.2 0.4 58.3 0.0 0.0 0.1 3.5 0.0 0.0 0.0 29.8 0.0 0.0 0.0 5.5 0.0 1.3 0.0 0.0 167.0 0.0 0.0 0.2 7.0 0.0 3.1 10.9 0.6 1.5 0.4 2.5 2.1 0.0 0.0 0.7 2.0 1.3 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 46.5 56.3 52.6 55.0 50.0 48.7 51.0 48.2 52.6 55.6 46.9 81.0 4.5 6.4 1.7 0.0 0.1 0.4 4.8 2.5 1.2 5.4 0.6 0.8 14.2 0.0 2.2 3.7 2.1 1.5 2.7 0.1 0.0 0.3 0.0 4.4 0.4 6.0 0.0 2.1 0.0 0.2 0.5 1.6 0.0 3.1 0.0 0.1 2.2 0.5 0.2 15.2 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.7 3.6 0.0 0.0 3.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.6 0.0 1.4 3.7 0.6 0.0 7.0 2.9 0.0 0.4 0.4 0.6 0.8 0.2 0.2 0.0 1.4 SCRIB "KIAA0147, SCRB1, Vartul" ENSG00000180900 "Scribble planar cell polarity protein" Q14160 8 143790920-143815773 "Disease related genes, Predicted intracellular proteins" "Differentiation, Host-virus interaction, Inhibition of host innate immune response by virus, Inhibition of host interferon signaling pathway by virus, Inhibition of host STAT1 by virus, Inhibition of host STAT2 by virus, Viral immunoevasion" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 100.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015463, CAB022081, HPA023557, HPA064312" Supported Enhanced "Nucleoplasm,Plasma membrane,Cell Junctions,Rods & Rings" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" "Nucleoplasm, Rods & Rings" "CAB015463: AB_2238926, CAB022081: , HPA023557: AB_2671238, HPA064312: AB_2685242" "unprognostic (1.24e-1)" "unprognostic (1.94e-2)" "unprognostic (7.78e-2)" "unprognostic (8.95e-2)" "unprognostic (3.77e-1)" "unprognostic (3.96e-2)" "unprognostic (1.14e-3)" "unprognostic (1.86e-2)" "unprognostic (2.46e-1)" "unprognostic (2.56e-1)" "unprognostic (8.22e-2)" "unprognostic (1.87e-1)" "unprognostic (2.16e-3)" "unprognostic (3.46e-3)" "unprognostic (1.99e-1)" "unprognostic (1.10e-1)" "unprognostic (1.83e-1)" 18.7 17.1 11.5 7.2 10.8 5.6 23.6 6.0 10.4 45.6 0.0 32.3 9.1 24.7 0.9 100.5 26.0 3.4 24.6 8.7 2.7 27.7 25.4 21.3 4.0 10.7 8.1 23.0 38.8 5.2 24.8 5.0 5.9 28.4 3.4 1.0 40.2 5.2 54.3 68.3 26.5 2.0 4.9 22.9 30.0 26.4 9.0 3.0 24.6 1.7 3.9 27.8 52.6 15.3 55.7 33.1 12.7 20.5 5.1 6.9 33.0 30.9 5.3 11.2 9.1 15.3 29.8 24.2 39.7 7.2 4.6 52.4 7.9 32.9 1.7 30.8 58.5 24.6 30.5 26.1 10.8 13.0 14.8 5.1 29.9 9.4 5.5 5.1 11.5 19.8 42.2 6.4 7.5 93.0 38.1 26.9 15.7 25.0 55.1 44.5 10.6 25.0 5.6 45.5 29.6 27.1 31.4 30.5 33.6 4.5 41.5 28.2 25.7 10.1 64.1 25.2 44.7 31.6 31.0 23.8 13.1 9.5 19.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.5 10.8 6.0 10.4 8.7 2.7 10.7 8.1 5.9 4.9 9.0 15.3 12.3 0.0 9.9 33.0 4.4 8.5 5.0 10.2 13.6 11.3 16.8 17.0 11.1 11.5 8.3 14.7 14.6 11.0 9.7 28.7 3.9 8.6 1.5 14.0 7.7 7.8 13.8 13.7 5.0 9.4 6.3 7.3 29.6 27.3 0.0 17.9 3.6 8.8 6.5 5.0 6.2 17.8 18.3 6.0 4.1 0.7 9.0 6.6 8.8 6.5 5.0 10.0 5.2 12.1 15.2 11.5 22.8 9.8 5.6 9.3 16.9 4.5 9.9 16.0 13.1 12.0 8.7 9.4 10.0 19.9 10.7 5.1 7.3 8.0 23.2 7.1 SEMA6C KIAA1869 ENSG00000143434 "Semaphorin 6C" Q9H3T2 1 151131685-151146664 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "skeletal muscle: 322.9;tongue: 96.9" "Cell type enhanced" "Detected in many" "Adipocytes: 12.9;Cardiomyocytes: 19.1;Cone photoreceptor cells: 20.9;Inhibitory neurons: 13.7;Skeletal myocytes: 12.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 14.1;HUVEC TERT2: 24.8;TIME: 11.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA076150, HPA077625" Approved "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 1500000 "Cluster 33: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 37: Myocytes - Muscle contraction" "Nucleoplasm, Plasma membrane" "Nucleoli fibrillar center, Cytosol" "HPA076150: , HPA077625: " "unprognostic (6.97e-2)" "unprognostic (8.40e-2)" "unprognostic (1.56e-3)" "prognostic unfavorable (3.27e-4)" "unprognostic (2.79e-1)" "unprognostic (2.88e-2)" "unprognostic (3.00e-2)" "unprognostic (1.24e-2)" "unprognostic (5.66e-3)" "unprognostic (4.25e-2)" "prognostic favorable (3.06e-5)" "unprognostic (3.72e-2)" "unprognostic (1.67e-2)" "unprognostic (6.12e-2)" "unprognostic (9.49e-2)" "unprognostic (1.10e-1)" "unprognostic (1.85e-1)" 8.8 2.8 7.7 1.8 6.7 1.2 7.9 21.9 9.4 12.0 1.0 7.6 13.7 10.5 1.4 5.5 10.7 3.7 38.8 7.9 5.4 12.1 12.4 5.1 1.7 5.0 5.0 14.8 3.6 2.1 13.4 1.9 4.9 8.3 1.8 5.2 8.5 2.3 322.9 8.9 10.8 6.2 2.2 3.0 5.4 32.2 7.3 2.2 4.7 96.9 0.9 8.4 8.8 5.3 0.9 1.0 14.1 5.4 5.8 1.9 1.3 1.0 0.5 0.9 1.3 0.3 0.6 0.7 4.0 3.3 2.0 1.4 1.3 0.5 0.8 1.3 4.2 7.7 0.7 1.2 0.8 0.1 2.7 3.3 1.7 1.2 0.6 2.8 24.8 4.1 0.7 0.7 2.3 0.5 1.3 1.0 6.3 0.2 1.7 9.0 3.1 0.3 0.5 0.4 7.1 9.3 1.3 0.6 1.2 3.5 1.6 1.3 11.8 2.3 3.3 3.5 0.6 5.9 1.2 6.1 0.6 0.3 0.8 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 6.7 21.9 9.4 7.9 5.4 5.0 5.0 4.9 2.2 7.3 5.3 12.9 0.0 2.8 3.9 1.0 1.7 0.8 0.3 0.6 5.7 1.9 3.0 19.1 1.5 0.8 0.0 20.9 0.2 0.6 0.1 0.0 0.3 0.6 0.4 2.8 10.2 0.0 0.8 6.7 0.4 0.6 4.4 0.5 0.4 0.0 9.9 6.8 5.3 0.4 6.7 13.7 0.3 0.0 2.5 0.7 3.1 5.6 0.5 1.8 4.7 0.4 1.9 1.0 5.5 1.5 0.4 0.0 2.6 1.9 0.5 3.3 2.9 0.3 7.5 0.0 12.0 2.9 3.3 1.2 0.5 1.0 0.1 0.8 0.5 0.8 0.5 SENP7 ENSG00000138468 "SUMO specific peptidase 7" Q9BQF6 3 101324205-101513241 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 109.6;Oligodendrocyte precursor cells: 157.3;Oligodendrocytes: 134.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 44.1" "Lineage enriched" "Detected in all" 4 "granulocytes: 44.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027259, HPA071998" Approved Supported "Nucleoplasm,Nuclear bodies,Centrosome,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "Nuclear bodies, Centrosome, Cytosol" "HPA027259: AB_1856679, HPA071998: " "unprognostic (1.50e-1)" "unprognostic (6.12e-2)" "unprognostic (2.78e-2)" "unprognostic (7.31e-2)" "unprognostic (2.44e-2)" "prognostic favorable (4.23e-4)" "unprognostic (1.38e-3)" "unprognostic (9.25e-3)" "unprognostic (8.80e-2)" "unprognostic (2.24e-1)" "unprognostic (7.77e-3)" "unprognostic (1.94e-1)" "unprognostic (9.85e-2)" "unprognostic (8.08e-3)" "unprognostic (3.27e-1)" "unprognostic (9.03e-2)" "unprognostic (2.23e-2)" 15.1 9.7 9.7 13.7 12.7 24.7 16.9 21.8 11.8 15.8 9.7 12.5 7.3 26.8 14.7 7.8 16.1 14.2 9.5 9.3 12.3 11.4 8.7 12.8 23.1 13.9 11.7 26.3 12.8 16.9 10.2 19.4 14.0 12.7 10.8 26.0 8.9 11.5 11.2 20.8 12.4 14.7 10.1 16.9 14.1 9.1 11.5 20.5 17.5 11.2 17.7 11.8 11.4 20.3 9.2 6.1 29.4 16.4 5.6 8.2 5.3 5.2 3.8 8.5 10.4 4.0 8.3 7.0 7.9 5.1 7.8 9.1 9.4 4.8 17.0 13.0 2.7 12.7 5.1 5.5 4.5 7.4 12.2 6.4 8.5 4.3 9.6 7.6 12.2 13.4 10.5 17.6 8.1 6.1 13.7 8.6 6.0 4.8 6.3 15.2 8.0 6.4 10.1 5.2 11.3 8.8 4.8 4.8 6.5 15.0 8.0 9.8 10.2 11.8 7.1 3.9 5.2 12.2 7.8 16.4 4.1 9.7 9.8 44.1 5.9 5.9 5.8 5.4 7.3 6.4 7.8 5.8 4.8 9.0 10.3 7.1 17.3 9.3 6.3 4.1 6.9 6.1 9.7 12.7 21.8 11.8 9.3 12.3 13.9 11.7 14.0 10.1 11.5 20.3 44.5 16.0 24.9 78.4 33.0 9.1 8.4 7.4 21.1 48.3 14.4 12.2 21.6 2.8 18.4 16.5 20.9 5.8 30.8 5.4 5.9 8.1 4.1 33.1 48.5 28.4 13.1 18.7 62.4 5.2 2.7 23.4 21.4 34.1 37.2 28.6 32.9 10.3 8.2 52.2 109.6 6.5 12.2 20.5 9.5 4.0 18.3 19.1 10.6 80.6 13.6 16.7 35.0 157.3 134.4 6.9 4.1 19.5 23.5 4.8 7.0 8.5 27.5 33.8 46.0 29.7 23.3 22.8 19.9 13.4 9.9 2.5 41.0 21.1 5.9 6.1 SEPTIN2 "DIFF6, hNedd5, KIAA0158, NEDD5, Pnutl3, SEPT2" ENSG00000168385 "Septin 2" Q15019 2 241315100-241354027 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Spermatogenesis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 89.9;Cardiomyocytes: 133.5;Cytotrophoblasts: 135.9;Extravillous trophoblasts: 190.1;Hofbauer cells: 136.8;Syncytiotrophoblasts: 139.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017190, HPA018481" Supported Enhanced "Nucleoplasm,Plasma membrane,Actin filaments,Cytokinetic bridge" Yes No 3300000 "Cluster 27: Non-specific - Gene expression" "Cluster 57: Non-specific - Angiogenesis" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 24: Non-specific - Transcription regulation" "Actin filaments" "Nucleoplasm, Plasma membrane, Cytokinetic bridge" "CAB017190: , HPA018481: AB_1856684" "unprognostic (6.31e-2)" "unprognostic (5.27e-2)" "unprognostic (2.95e-2)" "unprognostic (4.03e-2)" "prognostic favorable (8.21e-4)" "unprognostic (3.32e-1)" "prognostic unfavorable (3.66e-4)" "unprognostic (1.96e-3)" "unprognostic (1.83e-2)" "unprognostic (5.69e-2)" "unprognostic (1.11e-3)" "unprognostic (3.16e-1)" "unprognostic (9.58e-3)" "unprognostic (8.11e-2)" "unprognostic (9.53e-2)" "unprognostic (1.40e-1)" "unprognostic (2.17e-2)" 246.0 155.0 192.8 159.7 216.1 125.3 177.2 208.8 220.6 233.8 183.2 179.7 140.8 209.0 176.7 161.1 168.7 193.8 211.8 180.5 209.6 212.6 117.1 184.5 157.2 227.2 203.3 221.7 214.2 220.1 112.7 217.3 232.2 186.1 188.6 114.0 163.3 218.2 160.6 119.0 154.8 253.1 224.1 164.9 152.6 145.0 198.3 141.8 224.6 163.5 180.5 221.0 116.7 245.3 245.1 207.7 561.7 370.8 511.5 555.0 289.1 517.3 508.9 329.1 417.2 118.7 258.4 96.1 119.4 599.0 176.7 209.6 377.7 347.9 535.5 241.9 262.2 388.9 200.5 444.5 311.6 374.4 228.0 495.1 224.8 275.0 259.1 369.8 576.2 240.9 357.4 138.0 491.9 171.5 226.7 227.3 412.5 215.2 152.8 216.2 707.4 204.7 483.5 359.9 401.4 270.0 363.0 245.7 353.0 397.9 146.9 333.4 555.5 399.2 166.2 392.9 320.6 267.7 251.9 340.9 344.7 225.1 571.6 172.0 165.0 98.3 101.0 184.1 125.1 87.4 97.9 104.2 183.8 77.2 84.4 89.6 58.9 191.4 144.8 138.7 108.0 241.2 192.8 216.1 208.8 220.6 180.5 209.6 227.2 203.3 232.2 224.1 198.3 245.3 89.9 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 133.5 0.0 0.0 0.0 0.0 135.9 39.9 0.0 0.0 0.0 0.0 0.0 0.0 25.3 0.0 0.0 0.0 0.0 190.1 50.4 0.0 0.0 0.0 0.0 0.0 0.0 136.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.7 0.0 0.0 0.0 0.0 139.0 6.5 0.0 0.0 0.0 SGCE DYT11 ENSG00000127990 "Sarcoglycan epsilon" O43556 7 94524204-94656572 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 116.6;Oligodendrocyte precursor cells: 133.2;Oligodendrocytes: 116.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "gdT-cell: 2.1;memory B-cell: 4.4;naive B-cell: 6.6" "Group enriched" "Detected in many" 4 "B-cells: 6.6;T-cells: 2.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074790 Approved "Nucleoplasm,Golgi apparatus,Vesicles,Plasma membrane" Yes No 170000 "Cluster 19: B-cells - Humoral immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Golgi apparatus" "HPA074790: AB_2686713" "unprognostic (3.16e-3)" "unprognostic (9.06e-2)" "unprognostic (1.20e-1)" "unprognostic (1.20e-3)" "unprognostic (1.12e-1)" "prognostic unfavorable (1.61e-5)" "unprognostic (1.19e-2)" "unprognostic (2.82e-2)" "unprognostic (6.93e-2)" "unprognostic (3.37e-1)" "unprognostic (6.80e-3)" "unprognostic (9.69e-2)" "unprognostic (5.71e-2)" "prognostic unfavorable (1.35e-4)" "unprognostic (1.43e-1)" "unprognostic (2.04e-1)" "unprognostic (2.44e-2)" 43.2 63.4 19.9 9.4 21.6 0.4 36.5 22.1 31.6 45.1 20.9 51.6 8.0 43.2 27.1 13.3 40.7 27.6 38.9 19.6 21.0 19.5 14.4 30.5 16.7 23.2 20.6 92.2 21.5 10.9 30.9 52.7 22.4 18.0 12.8 16.8 21.1 31.6 8.5 8.2 19.2 41.8 21.9 25.1 23.8 18.5 20.4 12.8 23.9 19.8 7.2 35.6 34.6 26.7 13.5 42.5 39.6 61.8 63.7 110.8 7.1 51.3 92.3 40.7 60.4 24.9 78.0 12.8 70.4 86.5 83.7 9.4 60.0 21.6 49.1 2.2 32.7 1.4 36.9 28.3 44.0 4.3 0.0 95.5 31.1 64.8 79.3 104.9 30.8 0.0 0.1 93.7 43.5 42.6 0.0 0.0 32.8 8.0 29.0 19.8 51.0 25.8 78.6 13.6 26.2 20.8 0.0 52.2 65.1 44.2 17.6 0.8 0.0 131.1 45.1 11.8 81.7 50.8 67.9 14.8 51.4 0.2 74.2 0.7 0.0 0.1 2.1 0.0 0.8 4.4 0.6 1.0 0.0 6.6 0.2 0.7 0.3 1.0 0.1 0.2 0.2 0.3 19.9 21.6 22.1 31.6 19.6 21.0 23.2 20.6 22.4 21.9 20.4 26.7 39.2 70.5 33.3 66.9 6.1 5.0 18.4 16.8 1.8 18.6 9.7 44.4 18.6 30.0 28.3 20.2 4.2 90.2 1.4 0.0 5.9 42.5 1.6 4.0 17.1 18.8 1.2 0.4 85.2 4.3 26.1 116.6 1.5 6.6 2.5 37.3 58.2 11.2 6.3 20.2 68.5 0.1 12.2 2.5 7.3 3.7 75.5 1.4 51.6 15.9 0.0 31.5 0.0 133.2 116.3 2.1 0.0 58.3 2.6 5.5 0.0 14.1 13.7 30.3 85.5 68.0 60.7 17.1 13.0 0.9 4.0 82.8 2.7 44.0 0.0 2.2 SGMS1 "MGC17342, MOB, SMS1, TMEM23" ENSG00000198964 "Sphingomyelin synthase 1" Q86VZ5 10 50305586-50625163 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Lipid metabolism, Sphingolipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 153.1;Microglial cells: 229.5;Oligodendrocyte precursor cells: 313.1;Oligodendrocytes: 422.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 62.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045191 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 1: K-562 - Erythropoiesis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Nucleoli fibrillar center, Golgi apparatus, Cytosol" "HPA045191: AB_10959605" "unprognostic (1.13e-1)" "unprognostic (5.75e-2)" "unprognostic (1.87e-1)" "unprognostic (9.08e-2)" "unprognostic (8.69e-3)" "unprognostic (8.34e-2)" "unprognostic (7.98e-2)" "unprognostic (2.29e-1)" "unprognostic (1.30e-2)" "unprognostic (5.75e-2)" "unprognostic (9.20e-2)" "unprognostic (2.05e-1)" "prognostic favorable (1.95e-7)" "unprognostic (8.38e-2)" "unprognostic (1.95e-1)" "unprognostic (3.31e-1)" "unprognostic (3.05e-1)" 15.8 19.3 19.8 10.7 27.4 24.0 14.5 21.5 20.3 16.9 33.9 10.1 13.5 11.9 19.9 15.3 16.6 15.4 13.2 17.2 23.0 20.2 27.9 21.9 14.9 29.5 24.1 18.6 13.3 52.9 6.4 24.6 28.5 19.5 11.7 20.2 18.0 16.8 9.9 25.3 16.0 15.8 23.6 11.7 14.3 11.3 23.4 12.0 24.7 10.5 14.5 20.9 13.1 41.3 30.2 14.0 4.0 9.0 14.2 18.6 18.8 19.6 19.7 13.5 12.6 11.7 30.3 22.1 11.3 25.9 12.2 18.7 9.5 20.6 14.0 19.4 10.2 32.7 17.9 9.0 16.5 7.5 7.6 12.1 23.6 18.0 21.7 8.7 19.3 7.9 62.6 32.2 14.6 12.7 3.3 4.2 9.2 13.7 13.7 5.5 18.4 8.8 19.7 31.2 6.2 4.9 14.4 14.2 7.5 11.3 21.4 2.7 27.1 14.6 17.8 14.1 14.6 11.0 9.5 6.3 18.2 12.0 12.1 3.4 9.3 28.4 4.6 4.9 10.3 7.0 6.2 6.8 5.2 6.5 8.2 5.4 16.7 10.1 4.0 3.2 15.6 6.3 19.8 27.4 21.5 20.3 17.2 23.0 29.5 24.1 28.5 23.6 23.4 41.3 17.1 44.8 40.0 106.7 19.9 54.4 28.9 15.6 23.9 20.1 15.8 8.9 26.3 10.0 30.0 29.5 4.2 10.9 15.6 6.2 15.6 17.6 17.0 20.9 10.5 19.6 14.9 32.0 153.1 21.6 7.7 19.8 30.5 32.4 20.8 12.1 17.9 16.0 29.0 5.0 117.2 11.1 4.1 46.5 17.6 30.6 16.1 34.5 12.4 229.5 12.4 17.4 10.3 313.1 422.0 10.7 6.4 10.5 13.7 32.3 18.4 9.3 25.1 36.4 0.0 20.5 27.1 12.8 2.3 18.7 83.4 4.9 20.0 11.8 12.4 25.4 SH3TC1 FLJ20356 ENSG00000125089 "SH3 domain and tetratricopeptide repeats 1" Q8TE82 4 8182072-8241803 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 28.0" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 32.6;Kupffer cells: 33.7;Macrophages: 35.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 17.7" "Group enriched" "Detected in many" 5 "B-cells: 6.8;dendritic cells: 17.7;monocytes: 12.3" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 25.8;MOLT-4: 41.8;SK-MEL-30: 26.8;U-2197: 19.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA038132, HPA056807" Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" "Nucleoli, Nucleoli rim" "Nucleoplasm, Cytosol" "HPA038132: AB_10673041, HPA056807: AB_2683239" "unprognostic (2.46e-1)" "unprognostic (2.43e-1)" "unprognostic (1.61e-3)" "unprognostic (5.46e-2)" "unprognostic (2.26e-2)" "unprognostic (1.63e-1)" "unprognostic (1.04e-1)" "unprognostic (8.54e-2)" "unprognostic (8.21e-2)" "unprognostic (3.25e-1)" "unprognostic (1.46e-2)" "unprognostic (2.59e-2)" "unprognostic (4.24e-2)" "unprognostic (2.46e-1)" "unprognostic (3.77e-3)" "unprognostic (1.15e-2)" "unprognostic (4.29e-2)" 8.4 3.5 4.0 8.7 4.3 4.6 5.6 4.1 5.6 2.9 5.2 2.8 0.9 2.1 0.7 8.4 3.0 5.4 3.6 3.6 7.3 19.2 9.6 9.0 9.1 10.5 6.0 1.2 6.3 0.7 2.5 3.0 8.5 4.7 1.0 1.3 4.6 2.7 1.5 2.7 4.9 2.0 9.2 14.1 6.0 0.6 8.4 28.0 4.6 0.7 4.5 4.4 5.8 11.8 3.9 6.1 0.1 0.0 0.0 0.5 4.1 0.4 0.2 0.5 0.8 3.2 2.2 5.2 5.2 0.0 0.8 2.0 0.0 12.4 0.0 14.2 0.2 0.0 6.1 5.7 4.3 0.1 0.8 0.2 15.3 0.3 9.9 0.5 25.8 3.2 0.8 7.3 0.4 4.1 41.8 3.4 0.0 2.3 5.1 3.1 0.7 1.6 0.4 1.0 0.1 3.1 1.7 0.4 26.8 1.0 0.0 1.0 14.2 0.0 3.0 19.0 0.2 0.0 1.0 4.7 0.2 1.9 4.1 0.0 9.9 1.3 0.7 8.8 0.9 4.9 1.7 1.1 7.7 6.8 0.9 0.7 0.3 0.3 12.3 17.7 2.5 4.3 4.0 4.3 4.1 5.6 3.6 7.3 10.5 6.0 8.5 9.2 8.4 11.8 12.6 0.0 5.8 1.3 18.1 0.8 10.5 6.9 0.6 1.0 0.8 1.4 3.3 4.3 4.1 25.8 0.0 2.1 18.2 2.5 7.9 3.6 0.5 0.9 0.3 12.6 1.2 3.2 0.2 5.6 3.4 1.6 32.6 2.2 17.2 0.3 27.5 8.6 22.7 23.5 0.1 2.5 14.2 33.7 16.7 1.5 0.6 35.7 0.0 17.8 15.6 13.3 7.2 0.5 0.1 9.3 4.5 0.7 17.1 8.3 0.1 17.2 2.0 0.9 0.0 0.6 1.2 0.0 0.3 2.5 0.6 3.0 11.7 2.5 1.8 15.3 SIK2 "DKFZp434K1115, KIAA0781, LOH11CR1I, QIK, SNF1LK2" ENSG00000170145 "Salt inducible kinase 2" Q9H0K1 11 111602449-111730855 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 113.3;Excitatory neurons: 217.6;Inhibitory neurons: 132.4;Oligodendrocytes: 191.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "ASC diff: 50.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016026, HPA071049" Approved Approved "Nucleoplasm,Nuclear speckles,Vesicles,Intermediate filaments,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Vesicles" "Nuclear speckles, Intermediate filaments, Cytosol" "HPA016026: AB_1857321, HPA071049: " "unprognostic (2.35e-1)" "unprognostic (1.10e-1)" "unprognostic (1.08e-1)" "unprognostic (1.10e-2)" "unprognostic (1.59e-2)" "unprognostic (4.81e-2)" "prognostic favorable (4.93e-4)" "unprognostic (6.41e-2)" "unprognostic (1.87e-1)" "unprognostic (1.40e-2)" "unprognostic (3.72e-3)" "unprognostic (9.27e-2)" "prognostic favorable (1.17e-9)" "unprognostic (1.23e-1)" "unprognostic (2.79e-1)" "unprognostic (2.82e-3)" "unprognostic (2.13e-2)" 29.7 9.3 9.2 5.3 12.4 3.1 20.7 7.9 11.1 7.6 11.0 7.9 5.9 7.3 5.0 5.9 8.1 10.0 12.3 9.5 14.7 11.4 22.7 11.7 4.4 11.9 11.9 14.9 31.8 21.3 16.6 5.8 10.6 6.7 6.2 30.7 13.8 6.2 33.1 8.9 7.5 5.9 5.5 4.6 17.6 3.0 9.3 5.4 8.7 23.2 4.3 7.7 6.1 11.6 9.2 6.0 10.3 11.1 50.3 14.8 6.1 7.9 11.2 5.9 6.7 20.5 9.6 7.2 10.7 9.2 6.9 12.7 8.2 5.9 7.6 5.4 3.4 7.9 5.2 10.1 10.9 7.7 4.9 14.5 8.6 8.7 11.1 11.7 7.1 7.1 7.4 10.3 9.4 4.3 8.0 7.0 3.5 7.6 5.9 10.6 11.0 8.7 13.1 8.2 4.8 11.3 11.6 4.7 4.5 9.4 11.5 6.2 9.9 12.9 7.7 8.3 10.9 2.9 2.4 14.8 4.2 10.6 8.8 0.3 0.7 0.6 0.7 0.7 0.3 0.4 0.5 0.5 0.6 0.4 0.2 0.4 0.3 0.5 0.6 0.3 0.5 0.5 9.2 12.4 7.9 11.1 9.5 14.7 11.9 11.9 10.6 5.5 9.3 11.6 22.1 19.2 24.8 113.3 14.1 14.7 6.2 5.2 18.2 15.7 10.5 9.9 21.3 27.1 10.0 16.5 66.7 4.4 11.4 15.6 5.9 10.4 16.5 27.7 14.9 18.8 18.0 12.4 217.6 7.9 4.6 20.1 27.5 45.3 9.5 24.3 9.3 38.7 5.4 32.0 132.4 11.3 4.1 12.4 16.9 14.1 11.5 13.3 19.6 73.1 6.0 14.5 4.1 86.0 191.9 8.4 10.3 14.7 8.9 6.9 8.3 23.1 13.4 60.9 0.0 19.1 19.0 3.9 6.4 10.3 11.9 5.2 12.6 5.0 11.5 7.1 SIPA1 SPA1 ENSG00000213445 "Signal-induced proliferation-associated 1" Q96FS4 11 65638101-65650918 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 95.6" "Cell type enhanced" "Detected in many" "dendritic cells: 82.5;NK-cells: 88.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020833, HPA039867" Enhanced Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Plasma membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoli "Nucleoplasm, Golgi apparatus, Plasma membrane" "CAB020833: , HPA039867: AB_2676716" "unprognostic (6.10e-2)" "unprognostic (1.75e-1)" "prognostic unfavorable (9.42e-4)" "unprognostic (1.35e-2)" "unprognostic (2.93e-1)" "unprognostic (2.32e-2)" "unprognostic (3.35e-2)" "unprognostic (1.09e-1)" "unprognostic (3.30e-2)" "unprognostic (6.44e-2)" "unprognostic (5.85e-2)" "unprognostic (4.86e-2)" "prognostic unfavorable (3.52e-6)" "unprognostic (1.60e-1)" "unprognostic (2.78e-2)" "unprognostic (1.14e-2)" "unprognostic (1.49e-1)" 21.6 17.2 16.4 48.7 15.5 53.8 16.2 14.1 16.8 20.6 10.3 24.0 12.5 20.9 3.4 14.3 19.5 16.0 25.7 15.8 13.2 17.0 15.0 37.0 60.7 22.3 16.0 13.1 8.4 3.5 7.5 19.4 19.5 17.1 6.0 0.9 14.1 10.0 10.0 8.1 37.8 12.0 19.5 95.6 15.9 4.7 24.5 21.3 14.9 6.4 32.5 18.8 15.3 21.0 1.6 13.3 9.1 20.1 5.4 11.1 21.7 14.9 12.7 11.7 11.3 3.9 14.5 21.3 33.2 7.6 0.4 7.8 3.4 5.1 3.9 22.7 8.1 52.6 20.7 7.4 9.6 21.5 21.5 11.4 2.3 16.2 2.1 11.5 34.4 21.8 30.3 9.2 5.8 5.8 8.6 36.1 6.4 5.4 12.3 38.8 5.1 19.3 4.4 0.8 3.4 20.9 7.5 12.6 31.7 8.5 9.6 32.5 49.2 14.2 28.7 15.2 3.0 14.1 12.2 48.4 19.5 33.0 42.0 3.2 3.3 9.3 5.8 3.9 4.1 4.1 2.8 3.7 2.3 4.7 2.0 3.1 11.1 4.7 4.8 2.1 3.0 3.0 16.4 15.5 14.1 16.8 15.8 13.2 22.3 16.0 19.5 19.5 24.5 21.0 22.5 6.4 5.2 7.5 59.0 6.8 24.7 23.2 17.6 2.1 24.8 26.5 7.2 21.5 19.2 23.9 0.0 10.1 82.5 16.5 37.2 19.8 3.0 8.3 6.8 26.8 21.0 31.6 0.1 14.5 19.6 12.2 11.2 14.9 7.0 37.1 42.8 22.0 38.4 5.0 0.2 12.8 30.5 44.4 11.4 9.8 8.1 40.2 10.6 14.0 23.7 7.6 88.6 0.5 4.0 27.2 12.7 13.2 29.6 29.0 39.0 20.7 6.0 1.8 13.1 7.4 20.9 0.8 13.8 14.4 11.1 13.5 50.4 30.9 14.3 31.9 SIPA1L2 "KIAA1389, SPAR2" ENSG00000116991 "Signal induced proliferation associated 1 like 2" Q9P2F8 1 232397965-232630571 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 44.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 80.2;Inhibitory neurons: 95.9;Microglial cells: 183.6;Oligodendrocyte precursor cells: 104.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 69.7;NTERA-2: 53.9;WM-115: 46.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024181, HPA027224" Approved Approved "Nucleoplasm,Nuclear membrane,Nuclear bodies,Golgi apparatus" No NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Nuclear membrane, Nuclear bodies" "Golgi apparatus" "HPA024181: AB_1856886, HPA027224: AB_2672165" "unprognostic (2.34e-2)" "unprognostic (9.67e-2)" "unprognostic (8.02e-2)" "unprognostic (1.71e-3)" "unprognostic (2.98e-1)" "unprognostic (5.68e-2)" "unprognostic (5.57e-3)" "unprognostic (7.79e-2)" "unprognostic (1.60e-1)" "unprognostic (1.80e-2)" "unprognostic (3.77e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (8.15e-4)" "unprognostic (3.36e-2)" "unprognostic (2.75e-1)" "unprognostic (5.84e-3)" "unprognostic (3.45e-3)" 12.1 3.3 8.5 6.4 7.2 5.4 9.2 9.6 11.7 10.0 0.5 19.4 3.9 4.4 2.8 20.3 4.5 8.5 31.3 9.6 16.0 7.7 6.4 16.2 3.0 44.0 21.7 11.9 3.6 4.4 8.1 18.3 44.6 8.1 18.9 14.7 8.7 4.7 7.1 9.0 9.2 7.4 14.4 9.6 5.7 7.2 18.7 2.4 8.0 9.5 3.3 12.5 14.9 9.0 0.0 7.5 69.7 0.2 0.6 0.0 29.3 1.2 2.5 3.1 2.2 2.9 0.1 5.9 13.3 26.4 2.9 1.7 13.8 2.3 2.9 0.0 12.8 0.0 7.0 0.0 5.9 1.0 7.2 3.8 9.1 0.6 6.2 0.0 15.7 25.4 0.0 0.1 1.6 3.5 7.4 0.7 53.9 0.2 10.2 0.0 0.0 3.4 8.1 11.5 3.5 11.9 23.8 0.8 9.5 15.8 1.4 0.6 5.6 8.1 0.0 17.8 2.9 6.5 0.0 0.0 10.0 6.2 46.1 0.0 0.2 0.0 0.0 0.4 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.4 0.6 0.3 0.3 0.0 0.1 8.5 7.2 9.6 11.7 9.6 16.0 44.0 21.7 44.6 14.4 18.7 9.0 53.7 6.4 1.8 22.9 0.8 8.8 9.8 8.7 15.4 23.5 10.7 8.6 62.6 12.8 10.4 3.7 52.1 4.9 4.4 29.9 0.0 7.1 11.7 19.0 21.4 22.7 7.2 0.4 80.2 0.5 7.1 15.2 5.1 47.5 1.3 16.0 1.8 3.8 10.0 5.0 95.9 29.5 14.2 16.6 7.2 9.8 0.9 19.5 14.2 183.6 6.3 12.7 1.0 104.0 21.0 1.4 39.9 1.9 0.5 13.2 9.1 0.4 7.7 35.7 0.0 21.8 23.9 6.9 24.0 45.8 7.4 14.8 2.0 11.9 23.4 23.0 SIRT1 SIR2L1 ENSG00000096717 "Sirtuin 1" Q96EB6 10 67884656-67918390 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Biological rhythms, Differentiation, Host-virus interaction, Myogenesis, Transcription, Transcription regulation" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Early spermatids: 292.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003855, HPA006295, HPA052351" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Mitochondria,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Nucleoli fibrillar center, Mitochondria, Cytosol" "CAB003855: AB_365497, HPA006295: AB_1079975, HPA052351: AB_2681796" "unprognostic (1.55e-1)" "unprognostic (2.78e-1)" "unprognostic (9.13e-2)" "unprognostic (1.05e-1)" "unprognostic (1.91e-1)" "unprognostic (2.05e-2)" "unprognostic (2.48e-1)" "unprognostic (4.95e-2)" "unprognostic (1.41e-1)" "unprognostic (4.64e-2)" "unprognostic (1.72e-1)" "unprognostic (9.61e-2)" "unprognostic (2.18e-2)" "unprognostic (2.83e-2)" "unprognostic (9.67e-2)" "unprognostic (1.12e-1)" "unprognostic (1.39e-1)" 16.4 30.2 8.9 11.0 10.4 19.8 17.5 15.6 11.9 17.1 7.8 12.5 9.2 18.5 11.9 10.9 11.9 14.0 10.6 8.5 9.9 13.4 17.3 12.6 17.7 9.3 9.2 25.1 12.1 14.0 6.9 12.7 10.0 14.0 12.0 13.5 9.9 11.2 14.6 9.6 9.7 13.7 8.8 14.3 10.3 26.8 9.4 19.2 14.7 18.5 15.1 15.5 9.5 12.9 15.1 16.8 26.2 29.4 24.4 18.7 16.3 20.4 21.0 27.4 24.3 18.7 12.6 31.4 10.8 13.7 17.1 11.7 32.8 6.9 29.3 16.9 19.0 16.7 12.1 14.7 22.3 18.1 12.3 17.3 16.2 16.6 28.3 29.4 11.2 17.6 21.6 16.7 20.3 12.1 17.0 25.0 32.5 9.6 26.6 30.3 20.6 12.4 13.1 9.1 16.8 23.0 37.4 24.4 26.8 22.5 17.7 16.6 9.4 21.2 19.8 19.0 20.1 13.9 17.7 61.8 10.9 27.2 8.9 1.3 0.8 1.1 1.1 1.0 1.6 1.8 1.2 1.5 1.3 1.0 2.2 1.3 1.0 1.2 1.3 1.2 1.0 0.6 8.9 10.4 15.6 11.9 8.5 9.9 9.3 9.2 10.0 8.8 9.4 12.9 35.7 19.2 7.4 17.0 27.6 39.1 20.9 7.2 22.8 12.5 48.3 33.4 34.8 11.5 8.7 5.5 27.1 7.1 42.5 31.2 5.9 4.3 292.2 38.4 26.2 20.6 42.9 10.3 16.0 5.6 5.4 28.0 23.4 57.1 12.0 14.8 15.4 15.8 9.1 11.8 18.4 21.0 10.2 23.4 28.7 45.6 17.7 34.1 16.0 30.9 14.8 7.1 9.2 18.6 30.7 6.2 20.6 19.5 15.8 26.0 11.2 8.4 4.1 14.0 0.0 43.4 28.8 24.2 16.3 21.1 47.5 12.4 29.1 8.9 18.7 17.2 SKIV2L "170A, DDX13, HLP, SKI2W, SKIV2, SKIV2L1" ENSG00000204351 "Ski2 like RNA helicase" Q15477 6 31959117-31969751 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/70: 42.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047122, HPA051959, HPA054419" Uncertain Approved "Nucleoplasm,Nuclear bodies,Mitotic spindle,Cytosol" Yes NA "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 29: U-266 - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Nuclear bodies" "Mitotic spindle, Cytosol" "HPA047122: , HPA051959: AB_2681672, HPA054419: AB_2682482" "unprognostic (1.43e-1)" "unprognostic (5.75e-2)" "unprognostic (3.41e-2)" "unprognostic (1.66e-2)" "unprognostic (6.43e-2)" "unprognostic (7.03e-2)" "prognostic unfavorable (6.58e-4)" "unprognostic (3.36e-2)" "unprognostic (2.14e-2)" "unprognostic (7.75e-2)" "unprognostic (7.99e-3)" "unprognostic (1.53e-3)" "prognostic unfavorable (3.02e-7)" "unprognostic (6.77e-2)" "unprognostic (2.23e-1)" "unprognostic (1.20e-1)" "unprognostic (9.06e-2)" 21.9 33.1 0.0 5.2 0.3 4.1 21.6 0.0 0.4 26.5 0.0 25.1 10.5 22.6 9.4 23.0 25.0 0.0 22.0 0.0 0.1 24.0 54.7 22.2 3.4 0.0 0.5 24.6 25.7 2.4 39.7 2.6 0.0 31.9 2.4 2.1 22.4 3.2 20.4 20.2 31.2 5.7 0.0 40.6 27.6 16.6 0.1 4.3 27.7 5.3 2.7 23.6 20.9 0.0 0.2 12.7 13.3 0.0 16.5 11.8 27.1 10.9 11.7 13.6 13.2 0.4 0.0 0.0 26.0 25.5 13.2 11.9 0.0 30.8 9.9 14.8 15.7 0.0 0.0 0.2 0.0 0.1 0.2 28.3 17.9 0.1 0.0 12.7 0.0 19.3 0.0 13.6 0.0 0.0 0.0 0.3 20.6 0.0 0.0 0.3 0.0 0.0 11.2 0.0 0.0 0.0 23.6 0.0 17.6 11.5 0.0 15.7 12.8 16.0 7.2 18.7 0.2 42.2 35.7 12.0 20.4 0.1 0.0 0.3 0.5 0.2 1.5 1.4 1.1 0.2 0.7 0.3 1.1 0.9 0.8 0.8 0.1 0.0 2.2 0.5 0.2 0.4 0.0 0.3 0.0 0.4 0.0 0.1 0.0 0.5 0.0 0.0 0.1 0.0 6.4 16.0 11.3 10.1 13.3 2.8 5.0 7.9 11.4 5.0 9.3 5.1 8.5 10.0 8.8 7.3 8.4 12.6 12.7 19.7 1.9 9.5 3.1 7.7 7.9 7.9 12.6 6.5 7.2 8.6 7.9 7.4 28.1 6.3 8.2 10.8 8.6 19.4 9.2 0.0 5.0 13.2 8.2 6.3 4.1 1.5 9.3 7.8 7.2 2.8 10.2 4.9 18.6 3.0 4.8 9.4 16.0 6.0 20.2 5.9 25.5 6.9 16.5 8.3 0.0 4.1 10.2 4.7 7.5 6.6 3.7 12.4 14.4 12.3 11.0 5.2 SLC30A3 ZNT3 ENSG00000115194 "Solute carrier family 30 member 3" Q99726 2 27253684-27275817 "Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 22.2;epididymis: 68.5;testis: 35.2" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 8.4;Early spermatids: 17.8;Excitatory neurons: 15.6;Late spermatids: 42.4;Peritubular cells: 15.1;Spermatocytes: 16.6;Spermatogonia: 10.7" "Cancer enhanced" "Detected in some" "thyroid cancer: 1.3" "Group enriched" "Detected in many" 10 "amygdala: 14.5;basal ganglia: 10.3;cerebral cortex: 18.2;hippocampal formation: 22.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 8.8;HAP1: 11.2;Hep G2: 12.0;REH: 22.8;RH-30: 11.0" "Group enriched" "Detected in all" 4 "amygdala: 130.7;basal ganglia: 48.2;cerebral cortex: 110.9;hippocampal formation: 69.1;white matter: 34.7" "Group enriched" "Detected in many" 6 "amygdala: 18.5;cerebral cortex: 55.5;hippocampal formation: 43.0" "HPA060505, HPA067637, CAB079044" Enhanced Approved Approved Nucleoplasm,Nucleoli,Vesicles,Cytosol NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 14: REH - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "Nucleoplasm, Nucleoli, Cytosol" "CAB079044: , HPA060505: AB_2684296, HPA067637: AB_2685875" "unprognostic (2.05e-4)" "unprognostic (1.17e-1)" "unprognostic (6.84e-4)" "unprognostic (5.26e-2)" "unprognostic (2.34e-1)" "unprognostic (1.13e-1)" "unprognostic (1.43e-2)" "unprognostic (2.93e-2)" "unprognostic (2.64e-2)" "unprognostic (3.05e-1)" "unprognostic (2.20e-1)" "unprognostic (1.89e-1)" "unprognostic (4.65e-12)" "unprognostic (3.23e-2)" "unprognostic (1.76e-1)" "unprognostic (2.74e-2)" "unprognostic (2.63e-4)" 0.1 2.1 14.5 0.1 10.3 0.3 0.1 0.0 18.2 0.2 0.0 0.1 0.0 0.4 68.5 0.1 0.3 0.1 7.9 22.2 0.0 0.1 0.2 0.2 0.5 0.5 0.0 0.2 0.0 0.5 0.3 0.0 0.8 0.3 0.0 0.2 0.0 0.5 0.1 0.1 0.1 0.1 0.0 0.1 0.1 35.2 0.0 0.0 0.2 0.0 0.1 0.0 0.2 1.5 0.4 1.3 0.1 2.0 0.2 0.2 0.3 0.0 0.0 1.3 1.4 0.5 0.5 0.0 0.1 0.0 8.8 0.3 11.2 0.0 0.3 0.0 1.2 5.9 0.5 12.0 0.2 0.2 2.3 0.0 0.0 0.6 0.0 0.2 0.9 2.9 1.7 0.1 0.2 3.9 0.1 0.4 1.8 0.4 0.0 22.8 11.0 1.4 0.0 0.3 0.0 0.7 2.8 0.0 0.0 0.1 0.0 0.8 0.1 0.3 5.1 0.3 0.2 0.1 0.0 0.0 0.1 0.2 0.2 0.4 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.0 14.5 10.3 0.0 18.2 22.2 0.0 0.5 0.0 0.8 0.0 0.0 1.5 0.3 0.0 0.0 2.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.1 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 17.8 0.0 0.1 0.4 0.0 0.0 15.6 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 2.1 0.0 0.0 0.0 0.4 42.4 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 15.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.3 16.6 10.7 0.0 0.1 0.1 0.1 0.0 0.0 0.0 SLC34A1 "NAPI-3, NPT2, NPTIIa, SLC11, SLC17A2" ENSG00000131183 "Solute carrier family 34 member 1" Q06495 5 177379235-177398848 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 54 "kidney: 155.4" "Cell type enriched" "Detected in some" 14 "Proximal tubular cells: 143.2" "Cancer enriched" "Detected in single" 12 "renal cancer: 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "HEL: 2.4;U-937: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA051255, HPA077175" Approved Approved "Nucleoplasm,Nuclear speckles,Plasma membrane,Mitotic spindle,Cytosol" Yes NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 36: HEL - Hemostasis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles, Plasma membrane" "Nucleoplasm, Mitotic spindle, Cytosol" "HPA051255: AB_2681409, HPA077175: " "unprognostic (1.17e-1)" "unprognostic (3.33e-3)" "unprognostic (1.49e-1)" "unprognostic (3.49e-2)" "unprognostic (1.56e-3)" "unprognostic (2.28e-1)" "unprognostic (4.50e-2)" "unprognostic (4.43e-3)" "unprognostic (1.91e-1)" "unprognostic (1.14e-1)" "unprognostic (5.95e-2)" "unprognostic (1.23e-3)" "unprognostic (1.38e-1)" "unprognostic (2.01e-1)" "unprognostic (1.28e-2)" "unprognostic (4.66e-2)" 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 155.4 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 7.3 0.0 0.0 0.2 0.0 9.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 143.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.6 0.0 0.0 0.1 SLC5A1 "D22S675, NAGT, SGLT1" ENSG00000100170 "Solute carrier family 5 member 1" P13866 22 32043261-32113029 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Sugar transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "intestine: 528.1" "Cell type enriched" "Detected in many" 6 "Proximal enterocytes: 768.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 20.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 13 "OE19: 34.2" "Region enriched" "Detected in single" 26 "cerebellum: 7.6" "Low region specificity" "Detected in many" "CAB015467, HPA051805, HPA055106" Enhanced Approved "Nucleoplasm,Nuclear membrane,Golgi apparatus,Cytosol" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Golgi apparatus" "Nuclear membrane, Cytosol" "CAB015467: , HPA051805: AB_2681618, HPA055106: AB_2682695" "unprognostic (1.96e-1)" "unprognostic (1.04e-1)" "unprognostic (2.24e-2)" "prognostic favorable (2.59e-4)" "unprognostic (3.85e-2)" "unprognostic (2.75e-2)" "unprognostic (1.60e-2)" "unprognostic (2.15e-1)" "unprognostic (9.22e-2)" "unprognostic (4.83e-2)" "unprognostic (6.21e-2)" "unprognostic (9.53e-2)" "prognostic favorable (6.97e-7)" "unprognostic (4.68e-3)" "unprognostic (1.98e-1)" "unprognostic (6.00e-2)" "unprognostic (1.45e-2)" 0.1 0.0 0.1 4.2 0.1 0.0 9.7 0.2 0.1 12.3 0.0 10.7 528.1 0.5 3.5 5.1 1.1 26.9 75.2 0.1 0.0 6.6 1.7 2.1 0.3 0.1 0.0 0.0 1.6 0.3 1.0 0.0 0.1 3.0 9.7 0.2 19.0 2.4 0.3 13.5 302.4 0.7 0.0 2.9 7.2 2.3 0.5 0.1 0.0 0.0 4.0 0.0 6.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.6 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 34.2 0.0 0.0 0.0 2.1 0.0 0.0 0.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.5 0.2 0.1 0.0 0.0 0.3 0.2 0.6 1.7 4.2 0.0 0.0 11.6 6.5 115.2 115.8 8.2 0.0 0.0 0.0 0.2 19.8 0.0 3.0 38.4 2.4 1.4 1.0 25.4 0.0 0.4 1.4 0.0 1.4 5.6 10.3 0.0 0.0 0.0 0.3 0.0 0.0 0.3 34.1 0.0 0.0 0.0 71.3 1.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 32.6 1.5 0.0 17.6 768.7 6.4 2.0 0.0 0.0 0.0 0.7 10.1 4.2 2.0 5.5 0.0 0.1 0.1 41.2 6.7 SLC6A13 GAT2 ENSG00000010379 "Solute carrier family 6 member 13" Q9NSD5 12 220621-262873 "Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "kidney: 153.1" "Cell type enriched" "Detected in some" 6 "Proximal tubular cells: 324.9" "Cancer enriched" "Detected in some" 18 "renal cancer: 32.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "RPTEC TERT1: 4.6;SuSa: 1.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036449, HPA052726" Supported Nucleoplasm,Nucleoli,Mitochondria,Cytosol NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "Nucleoplasm, Nucleoli, Cytosol" "HPA036449: AB_2675130, HPA052726: AB_2681927" "unprognostic (8.45e-3)" "unprognostic (4.20e-1)" "unprognostic (5.44e-2)" "unprognostic (1.64e-5)" "unprognostic (1.13e-1)" "unprognostic (8.02e-2)" "unprognostic (1.32e-2)" "unprognostic (1.30e-1)" "unprognostic (1.75e-1)" "unprognostic (2.15e-1)" "unprognostic (7.21e-4)" "unprognostic (2.93e-1)" "unprognostic (1.25e-3)" "unprognostic (3.79e-2)" "unprognostic (2.62e-1)" "unprognostic (6.23e-2)" "unprognostic (1.91e-1)" 0.2 0.3 13.4 0.0 16.5 0.1 0.1 11.0 20.1 0.1 13.9 0.1 2.6 0.1 0.3 0.0 7.1 0.0 2.6 12.2 11.9 153.1 36.8 0.8 0.0 11.6 12.6 0.2 0.0 0.0 3.0 0.0 11.7 0.5 0.0 1.1 0.1 0.1 0.5 0.2 0.6 0.0 12.1 0.3 0.1 3.1 13.8 0.1 6.3 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.4 1.6 0.0 0.0 0.1 0.0 0.5 0.0 0.2 0.6 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 16.5 11.0 20.1 12.2 11.9 11.6 12.6 11.7 12.1 13.8 11.7 0.0 0.0 0.6 1.3 1.9 0.0 0.0 0.4 0.0 0.4 0.1 0.1 1.5 0.0 0.1 18.4 2.1 0.0 0.1 0.0 49.0 0.0 1.4 0.6 0.1 0.2 0.0 5.3 3.6 0.0 0.0 0.3 0.0 0.6 0.0 0.0 1.8 27.0 0.0 0.0 1.2 0.0 2.0 1.6 0.0 0.6 0.3 1.7 0.0 17.8 0.0 0.0 0.0 1.5 1.3 0.0 0.0 0.0 0.0 0.1 0.5 324.9 0.7 0.7 0.0 0.4 0.1 0.6 0.4 0.0 0.0 0.3 0.9 0.0 0.0 0.0 SLC7A14 "KIAA1613, PPP1R142" ENSG00000013293 "Solute carrier family 7 member 14" Q8TBB6 3 170459548-170586075 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 15.9;pituitary gland: 7.3;retina: 6.1" "Group enriched" "Detected in some" 5 "Bipolar cells: 28.4;Excitatory neurons: 61.9;Horizontal cells: 28.6;Inhibitory neurons: 90.2;Oligodendrocytes: 67.4" "Group enriched" "Detected in some" 11 "glioma: 0.8;pancreatic cancer: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "LHCN-M2: 3.2;SCLC-21H: 3.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045929 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Cytosol" "Nucleoplasm, Plasma membrane" "HPA045929: AB_2679501" "unprognostic (1.00e-1)" "unprognostic (9.56e-2)" "unprognostic (1.03e-1)" "unprognostic (4.15e-2)" "unprognostic (1.43e-2)" "unprognostic (7.46e-2)" "unprognostic (9.16e-2)" "unprognostic (1.13e-1)" "unprognostic (1.29e-1)" "unprognostic (6.68e-3)" "unprognostic (6.36e-2)" "unprognostic (3.03e-6)" "unprognostic (1.54e-2)" "unprognostic (8.05e-2)" "unprognostic (1.71e-2)" "unprognostic (3.24e-3)" 0.0 2.3 8.9 0.4 8.1 0.1 0.0 5.5 8.8 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 7.9 15.9 0.1 0.0 0.0 0.0 15.6 6.4 0.1 0.7 0.0 7.3 0.0 14.9 0.1 0.4 6.1 0.0 0.0 0.1 0.1 0.3 0.1 4.0 0.0 0.2 0.1 8.9 0.0 0.0 0.0 0.0 0.0 0.1 7.7 0.0 0.0 0.1 0.0 0.5 0.9 0.0 0.3 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.5 0.3 0.1 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.9 8.1 5.5 8.8 7.9 15.9 15.6 6.4 14.9 4.0 8.9 7.7 0.8 3.2 2.2 4.6 0.1 0.4 0.3 0.1 0.0 28.4 0.1 0.0 1.0 0.0 2.5 0.0 2.1 0.1 0.1 0.0 0.0 0.0 0.6 0.2 0.2 0.5 1.8 0.0 61.9 0.0 0.1 0.4 0.0 0.1 2.5 0.1 0.4 0.9 0.0 28.6 90.2 0.1 0.0 0.0 1.2 0.6 2.1 0.4 3.6 6.5 0.0 1.8 0.0 9.5 67.4 0.1 1.2 2.6 0.1 0.3 0.1 0.2 3.0 4.3 0.0 0.7 0.5 0.0 0.2 0.0 0.6 0.0 0.4 0.1 0.0 0.2 SMOX "C20orf16, dJ779E11.1, FLJ20746, MGC1010, PAO, PAOh1, SMO" ENSG00000088826 "Spermine oxidase" Q9NWM0 20 4120980-4187747 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 61.3" "Cell type enhanced" "Detected in many" "Ductal cells: 48.4;Erythroid cells: 89.7;Macrophages: 73.3;Pancreatic endocrine cells: 131.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 1.0;myeloid DC: 2.4;neutrophil: 3.6;plasmacytoid DC: 1.1" "Group enriched" "Detected in many" 6 "dendritic cells: 2.4;granulocytes: 3.6;monocytes: 1.0" "Cell line enhanced" "Detected in many" "A549: 119.6;Karpas-707: 201.7;RPTEC TERT1: 91.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047117, HPA060198" Approved Supported "Nucleoplasm,Nuclear membrane,Vesicles,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm "Nuclear membrane, Vesicles, Cytosol" "HPA047117: AB_2679940, HPA060198: AB_2684220" "unprognostic (1.24e-2)" "unprognostic (6.55e-2)" "unprognostic (7.24e-3)" "unprognostic (2.77e-1)" "unprognostic (1.40e-1)" "unprognostic (2.32e-1)" "prognostic unfavorable (3.33e-6)" "prognostic unfavorable (1.36e-4)" "unprognostic (4.92e-2)" "unprognostic (3.37e-1)" "unprognostic (7.18e-2)" "unprognostic (7.58e-2)" "prognostic unfavorable (1.06e-4)" "unprognostic (4.08e-2)" "unprognostic (2.64e-3)" "unprognostic (1.26e-2)" "unprognostic (3.07e-1)" 8.5 4.4 50.9 4.4 61.3 32.2 5.3 54.5 60.9 17.7 32.8 5.6 10.6 10.8 7.1 8.5 7.4 15.1 6.8 46.3 51.7 20.5 8.5 4.9 4.8 56.6 54.4 12.5 32.5 25.2 13.2 6.2 53.7 12.2 1.2 2.9 12.1 7.9 4.3 11.9 8.1 4.0 53.0 6.4 20.1 5.8 55.5 4.3 6.8 2.8 2.6 8.2 12.4 54.1 11.0 119.6 8.3 6.3 5.5 8.2 14.6 15.6 29.8 11.1 7.4 49.5 29.6 0.0 5.1 14.4 18.0 21.6 6.8 7.5 4.8 0.0 3.5 21.5 4.1 50.6 35.0 4.1 8.3 31.3 13.1 23.1 9.8 13.4 19.8 16.7 4.8 201.7 6.7 3.3 8.1 12.1 10.2 10.7 16.3 7.3 10.3 29.1 91.4 8.3 1.6 7.2 28.9 3.4 54.1 4.2 0.3 5.1 24.0 12.7 12.0 2.3 12.2 9.1 1.7 0.1 10.6 5.4 9.8 0.0 1.0 0.2 0.0 0.4 0.0 0.1 0.2 0.2 2.4 0.0 0.0 0.0 3.6 0.3 0.1 1.1 0.0 16.0 50.9 61.3 54.5 60.9 46.3 51.7 56.6 54.4 53.7 53.0 55.5 54.1 4.4 0.0 0.5 38.5 3.8 12.6 12.0 14.4 6.8 0.5 6.9 4.6 1.7 12.8 6.3 11.0 0.0 0.4 0.2 1.4 0.0 48.4 4.0 9.2 15.8 11.2 6.0 89.7 1.6 30.5 0.8 11.3 6.6 18.7 5.7 10.4 13.6 2.3 20.6 0.0 3.5 3.0 6.1 3.1 10.2 7.7 14.6 73.3 8.8 5.6 22.6 25.4 1.0 9.0 6.2 131.3 1.5 13.5 7.4 13.1 4.0 3.8 1.2 1.4 0.0 2.7 10.2 19.1 7.8 2.1 10.5 0.3 2.1 1.9 3.7 12.6 SMYD4 "KIAA1936, ZMYND21" ENSG00000186532 "SET and MYND domain containing 4" Q8IYR2 17 1779485-1830634 "Predicted intracellular proteins, Predicted membrane proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030059 Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "Nucleoplasm, Cytosol" "HPA030059: AB_2191728" "unprognostic (1.45e-1)" "unprognostic (2.48e-1)" "unprognostic (2.47e-1)" "unprognostic (4.23e-2)" "unprognostic (1.13e-2)" "unprognostic (3.66e-2)" "unprognostic (4.03e-2)" "unprognostic (1.04e-1)" "unprognostic (1.79e-2)" "unprognostic (4.95e-2)" "unprognostic (1.83e-3)" "unprognostic (9.26e-3)" "unprognostic (3.63e-2)" "unprognostic (1.33e-2)" "unprognostic (7.35e-2)" "unprognostic (1.52e-1)" "unprognostic (1.18e-1)" 7.4 6.6 4.1 6.0 3.6 3.4 7.3 8.0 4.5 7.9 3.7 7.5 7.0 6.5 5.0 3.9 7.3 3.6 7.0 3.5 3.5 3.7 4.9 5.6 6.8 3.7 3.2 9.5 6.7 3.6 6.6 4.7 4.0 6.5 4.8 7.6 7.3 5.6 13.7 6.6 7.4 5.9 2.2 6.3 4.9 5.8 4.3 6.2 5.7 10.2 6.5 7.2 6.2 5.6 7.4 13.7 13.5 9.6 9.0 6.1 15.7 11.9 6.7 12.3 12.5 22.0 6.2 19.7 7.8 4.8 8.3 14.2 12.9 7.7 15.3 5.7 13.1 7.2 15.9 6.0 4.5 7.4 6.8 4.4 6.8 12.7 11.1 6.3 6.2 16.6 7.6 7.5 9.7 4.6 13.6 5.3 6.2 8.7 6.6 16.7 6.9 5.0 4.9 8.8 5.5 7.6 11.0 4.5 11.1 10.9 6.7 4.5 5.9 12.0 6.1 10.0 10.4 5.2 7.5 7.1 6.8 6.4 11.9 12.0 2.4 2.3 5.1 3.0 4.3 4.0 3.0 3.3 1.5 2.7 3.4 5.0 1.3 3.1 2.4 4.5 3.5 2.1 4.1 3.6 8.0 4.5 3.5 3.5 3.7 3.2 4.0 2.2 4.3 5.6 22.9 6.4 27.8 6.5 12.9 5.0 9.3 11.9 14.8 19.3 6.9 8.4 6.3 14.3 14.0 7.3 33.3 9.7 16.5 6.9 1.9 5.7 20.2 3.7 8.9 10.9 3.6 9.7 11.7 3.3 10.9 14.2 4.1 3.5 7.6 14.7 17.2 6.7 12.9 26.9 12.1 5.2 12.2 23.3 9.2 5.9 27.1 17.4 5.4 13.1 16.4 7.9 43.3 4.5 7.1 4.2 2.0 24.8 10.1 7.2 23.3 2.9 17.8 19.9 46.0 43.6 23.9 12.6 14.8 5.1 6.7 8.1 12.1 6.1 6.4 3.5 SNRK "FLJ20224, HSNFRK, KIAA0096" ENSG00000163788 "SNF related kinase" Q9NRH2 3 43286512-43424764 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Sertoli cells: 124.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 126.0;TIME: 74.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042163 Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Vesicles, Plasma membrane, Cell Junctions" Nucleoplasm "HPA042163: AB_10794645" "prognostic favorable (9.28e-4)" "unprognostic (8.46e-2)" "unprognostic (2.79e-3)" "unprognostic (6.41e-2)" "unprognostic (1.14e-1)" "unprognostic (1.16e-3)" "unprognostic (2.00e-2)" "unprognostic (1.08e-1)" "unprognostic (2.63e-3)" "unprognostic (4.25e-1)" "unprognostic (2.32e-1)" "unprognostic (4.68e-2)" "prognostic favorable (9.41e-5)" "unprognostic (9.21e-3)" "unprognostic (2.04e-1)" "unprognostic (7.06e-3)" "unprognostic (7.38e-2)" 37.6 10.3 9.7 17.2 9.7 58.4 26.5 27.7 13.2 21.7 9.8 14.6 16.1 23.1 7.8 19.7 13.6 20.4 16.3 9.5 12.5 20.0 25.4 26.4 19.8 14.0 11.5 14.4 22.7 18.5 11.4 33.3 14.7 11.2 11.9 18.8 11.4 10.8 14.3 30.3 17.2 22.9 9.5 33.0 14.4 11.1 13.2 40.5 27.3 21.6 14.7 19.8 21.7 8.7 8.4 5.0 9.1 8.8 26.6 9.5 8.7 8.8 14.8 9.4 9.1 6.9 11.8 13.2 6.8 11.2 6.2 5.3 10.7 18.9 9.6 15.1 8.8 15.0 9.1 8.1 13.8 17.1 16.1 10.5 12.7 10.6 17.9 9.5 126.0 14.9 6.7 14.9 8.7 4.4 17.3 15.0 10.1 4.6 22.6 11.7 6.7 14.0 24.2 14.1 6.4 13.4 7.7 8.1 11.1 7.9 5.5 21.4 74.1 8.2 8.3 9.5 10.4 23.7 18.3 11.0 5.8 20.1 12.0 9.4 4.2 7.6 9.5 7.5 13.0 3.6 8.3 9.6 4.0 3.6 12.1 13.1 27.7 11.0 7.1 1.2 9.7 9.7 9.7 9.7 27.7 13.2 9.5 12.5 14.0 11.5 14.7 9.5 13.2 8.7 88.4 32.1 24.1 30.0 29.0 52.8 10.3 6.4 12.5 52.1 9.7 8.6 17.7 15.7 15.0 16.5 16.7 7.7 57.6 37.0 11.7 10.9 50.4 23.3 16.2 84.2 10.8 10.3 21.6 8.9 3.2 16.4 12.8 19.8 14.5 8.9 98.6 25.2 13.7 30.3 43.2 10.7 12.2 24.8 19.0 7.5 12.5 26.5 23.2 34.7 21.9 16.3 65.9 24.6 10.7 11.2 20.6 11.7 27.3 12.7 25.2 12.2 19.2 18.3 124.9 31.3 49.1 11.1 16.2 13.7 51.3 8.2 61.2 9.5 11.1 18.0 SOX15 "SOX20, SOX26, SOX27" ENSG00000129194 "SRY-box transcription factor 15" O60248 17 7588178-7590094 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 87.4;skin 1: 48.2" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 209.2;Basal squamous epithelial cells: 447.3;Squamous epithelial cells: 388.1;Suprabasal keratinocytes: 169.9" "Cancer enhanced" "Detected in many" "testis cancer: 67.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 6.7;non-classical monocyte: 10.6" "Lineage enriched" "Detected in many" 5 "monocytes: 10.6" "Group enriched" "Detected in many" 8 "A-431: 130.6;HaCaT: 142.1;HBEC3-KT: 57.8;hTCEpi: 56.6" "Not detected" "Not detected" "HPA067196, HPA074049" Enhanced Supported "Nucleoplasm,Nucleoli,Golgi apparatus,Vesicles" Yes NA "Cluster 51: Monocytes - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "Nucleoli, Golgi apparatus, Vesicles" "HPA067196: AB_2685802, HPA074049: AB_2686656" "unprognostic (5.79e-3)" "unprognostic (6.65e-2)" "unprognostic (1.40e-2)" "unprognostic (2.58e-2)" "unprognostic (2.72e-1)" "unprognostic (1.60e-1)" "unprognostic (6.02e-2)" "unprognostic (2.81e-2)" "unprognostic (5.00e-2)" "unprognostic (8.50e-2)" "unprognostic (1.59e-1)" "unprognostic (1.24e-1)" "unprognostic (8.61e-3)" "unprognostic (1.03e-1)" "unprognostic (1.96e-1)" "unprognostic (2.95e-2)" "unprognostic (2.97e-1)" 2.2 0.9 15.0 0.8 14.6 2.7 3.4 17.4 23.3 21.1 11.8 12.4 0.7 8.2 1.7 87.4 11.0 1.0 8.6 14.5 15.3 1.7 1.3 1.5 0.5 14.3 15.0 15.3 1.0 0.2 7.9 0.3 14.1 12.1 0.5 5.0 14.6 7.1 2.3 48.2 3.5 1.3 14.5 1.1 4.7 2.6 14.7 1.0 2.3 1.8 2.8 10.4 32.7 15.0 130.6 3.2 1.8 1.0 0.1 0.3 9.6 1.4 0.5 1.1 1.7 2.5 0.8 0.4 1.2 0.1 0.4 142.1 0.1 57.8 0.4 3.3 3.9 0.5 1.7 0.5 0.2 0.3 2.6 0.0 56.6 0.7 11.9 3.6 0.0 2.6 2.9 0.8 0.2 0.9 0.6 1.5 3.6 0.3 0.7 1.6 1.8 1.0 2.7 0.7 0.8 2.2 1.5 0.5 0.7 5.5 1.1 1.0 1.6 1.3 2.3 1.6 4.4 0.9 1.5 1.6 4.4 1.7 3.2 0.1 2.1 0.0 0.0 6.7 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 10.6 1.0 0.0 0.4 15.0 14.6 17.4 23.3 14.5 15.3 14.3 15.0 14.1 14.5 14.7 15.0 0.8 0.0 0.0 2.6 0.1 209.2 51.8 72.7 447.3 13.6 6.3 13.0 4.7 0.0 20.6 1.8 14.6 1.7 0.7 0.5 1.9 0.1 0.2 0.4 4.9 3.1 1.2 0.0 8.1 0.5 2.0 10.4 0.0 0.4 0.0 1.3 1.4 0.0 0.4 10.1 7.7 0.4 10.2 1.2 19.3 1.1 31.4 0.9 26.6 1.0 1.2 50.0 0.0 4.0 2.4 0.5 0.1 36.9 4.9 21.2 0.3 0.2 16.2 9.4 32.9 7.8 7.1 0.7 10.9 388.1 169.9 1.1 1.1 0.6 0.8 73.8 SPECC1 "CYTSB, FLJ36955, HCMOGT-1, NSP" ENSG00000128487 "Sperm antigen with calponin homology and coiled-coil domains 1" Q5M775 17 20008865-20319026 "Disease related genes, Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 47.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 217.1;Inhibitory neurons: 220.8;Microglial cells: 187.4;Oligodendrocytes: 317.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 42.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SiHa: 75.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021421, HPA021430, HPA061073" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" NA NA 9800 "Cluster 46: Basophils - DNA binding" "Cluster 65: Brain - Ion transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Vesicles" "Nucleoli fibrillar center, Cytosol" "HPA021421: AB_1857431, HPA021430: AB_1857432, HPA061073: " "unprognostic (1.13e-3)" "unprognostic (2.39e-1)" "unprognostic (1.98e-2)" "unprognostic (8.10e-3)" "unprognostic (8.32e-2)" "unprognostic (1.38e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.06e-5)" "unprognostic (9.29e-2)" "unprognostic (5.81e-2)" "unprognostic (6.23e-3)" "unprognostic (2.65e-1)" "unprognostic (3.15e-1)" "unprognostic (6.86e-2)" "unprognostic (1.79e-1)" "unprognostic (1.40e-1)" "unprognostic (2.04e-1)" 12.5 9.6 30.8 7.3 35.1 23.6 9.2 24.1 43.7 6.1 22.3 15.1 9.8 12.8 4.7 9.2 8.3 14.8 5.0 41.4 21.4 4.7 1.2 5.7 5.3 32.8 25.8 16.6 4.8 3.3 6.4 3.6 24.5 6.1 10.0 6.1 6.2 5.0 5.1 3.6 10.5 9.5 21.0 13.5 10.3 22.8 41.1 3.0 5.2 2.8 5.2 4.6 4.3 47.3 26.2 37.3 15.7 7.2 14.7 6.9 29.1 10.0 12.4 12.4 21.4 67.6 17.1 1.5 45.3 11.4 24.3 21.1 10.7 33.4 3.7 12.8 18.5 14.5 34.4 10.5 4.9 1.3 5.6 10.6 36.9 10.2 24.9 46.8 0.0 4.4 1.0 15.1 10.4 24.0 0.3 5.3 14.5 17.0 6.3 11.8 49.5 23.6 32.2 11.4 7.1 6.9 75.7 35.6 13.9 62.2 26.3 9.1 0.3 0.5 21.1 0.9 30.8 5.4 11.7 0.9 19.1 12.6 6.5 42.1 15.8 33.0 2.2 8.4 3.2 1.8 1.5 3.4 26.6 1.4 1.0 1.4 11.1 13.0 7.9 4.6 0.6 5.5 30.8 35.1 24.1 43.7 41.4 21.4 32.8 25.8 24.5 21.0 41.1 47.3 28.7 22.4 14.7 170.4 5.7 5.5 12.5 22.0 10.8 7.4 5.8 4.7 10.3 7.2 21.1 18.4 68.8 5.5 10.2 56.8 9.8 30.9 100.0 40.1 44.1 13.1 7.7 82.5 217.1 36.3 11.5 18.6 34.1 64.1 116.4 29.5 3.9 0.2 22.0 0.0 220.8 54.8 12.2 12.4 15.9 54.5 5.0 29.0 21.4 187.4 84.7 13.6 11.3 125.2 317.8 67.7 24.7 44.8 7.0 19.7 25.2 3.6 18.1 31.4 59.2 7.3 81.3 73.8 68.9 5.9 2.6 2.2 10.0 87.8 27.4 21.5 SPON1 "f-spondin, KIAA0762" ENSG00000262655 "Spondin 1" Q9HCB6 11 13962723-14268133 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 101.4" "Cell type enhanced" "Detected in many" "Astrocytes: 399.9;Endometrial stromal cells: 78.9;Muller glia cells: 141.9" "Cancer enriched" "Detected in all" 5 "ovarian cancer: 199.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "MAIT T-cell: 3.3" "Lineage enriched" "Detected in single" 33 "T-cells: 3.3" "Group enriched" "Detected in some" 36 "EFO-21: 213.7;RPTEC TERT1: 604.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038584, HPA077546" Uncertain Approved "Nucleoplasm,Nucleoli,Actin filaments,Microtubule ends,Cytokinetic bridge" "Secreted to blood" Yes No 11500000 28000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoli, Microtubule ends" "Nucleoplasm, Actin filaments, Cytokinetic bridge" "HPA038584: AB_10697394, HPA077546: AB_2732351" "unprognostic (1.66e-1)" "unprognostic (1.03e-2)" "unprognostic (8.36e-2)" "unprognostic (8.72e-2)" "unprognostic (1.52e-1)" "unprognostic (3.76e-2)" "unprognostic (1.82e-1)" "unprognostic (8.20e-2)" "unprognostic (1.05e-1)" "unprognostic (5.93e-2)" "unprognostic (6.45e-2)" "unprognostic (1.07e-1)" "prognostic favorable (3.12e-4)" "unprognostic (7.22e-3)" "unprognostic (7.89e-2)" "unprognostic (4.65e-2)" "prognostic unfavorable (1.88e-4)" 54.2 16.9 25.8 18.6 33.7 0.1 19.5 26.3 22.3 43.8 7.8 31.8 31.6 36.5 15.2 17.3 63.1 101.4 30.6 28.2 28.3 12.2 2.0 49.2 1.6 25.6 33.6 23.9 4.6 0.8 10.0 41.3 26.4 16.9 46.6 63.8 7.0 8.8 0.8 8.8 28.4 46.9 14.9 8.3 28.8 2.5 34.0 1.7 5.2 1.6 1.2 51.5 12.5 21.8 0.1 0.1 0.4 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 9.8 0.2 0.2 213.7 0.0 0.2 0.4 0.0 0.0 0.0 0.3 1.9 0.0 0.1 0.1 0.0 0.0 0.1 11.4 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.1 2.7 0.0 0.1 1.7 0.0 0.1 604.1 0.1 0.1 0.2 0.0 0.0 0.0 4.1 0.0 0.1 2.6 0.2 0.7 0.5 0.3 0.3 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.3 0.0 0.6 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 25.8 33.7 26.3 22.3 28.2 28.3 25.6 33.6 26.4 14.9 34.0 21.8 0.2 0.0 2.3 399.9 13.5 0.0 17.3 0.0 1.2 13.5 2.0 5.5 1.9 5.7 0.0 0.0 2.1 3.4 4.8 38.9 3.9 4.3 1.5 36.1 78.9 2.5 16.7 0.0 17.0 2.0 4.2 41.2 0.5 61.5 2.5 1.8 2.5 0.2 1.9 1.7 16.8 24.0 0.0 0.3 0.0 1.3 4.4 1.0 0.0 11.2 0.5 141.9 20.6 62.4 1.6 6.8 20.6 30.1 0.9 9.0 18.4 2.1 0.7 26.8 6.6 5.8 7.0 0.4 0.8 0.6 0.0 4.9 7.8 1.1 40.9 9.4 SPRYD3 FLJ14800 ENSG00000167778 "SPRY domain containing 3" Q8NCJ5 12 53064316-53079404 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039426, HPA039685" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "Vesicles, Plasma membrane, Actin filaments" "HPA039426: AB_10673358, HPA039685: AB_2676623" "unprognostic (7.73e-3)" "unprognostic (6.55e-2)" "unprognostic (1.37e-2)" "unprognostic (5.05e-3)" "unprognostic (1.52e-2)" "prognostic unfavorable (9.46e-4)" "unprognostic (1.27e-3)" "unprognostic (2.58e-1)" "unprognostic (1.83e-2)" "unprognostic (1.43e-2)" "unprognostic (2.64e-2)" "unprognostic (3.14e-2)" "prognostic favorable (1.78e-15)" "unprognostic (9.82e-2)" "unprognostic (5.27e-2)" "unprognostic (7.44e-3)" "unprognostic (1.41e-1)" 32.2 29.2 70.6 18.4 77.9 6.4 30.2 35.6 84.2 33.6 38.1 32.8 18.9 38.1 36.2 31.7 45.1 20.4 42.4 79.9 60.4 29.5 22.1 23.6 17.4 61.7 55.1 43.5 50.0 43.3 60.7 14.0 61.5 34.5 17.0 39.3 43.9 40.6 21.2 27.0 23.4 31.6 43.8 24.3 35.8 11.5 58.0 13.7 34.6 23.1 20.6 36.5 30.7 67.9 28.4 43.0 5.6 11.5 45.4 22.4 7.3 42.6 22.2 16.1 10.1 7.4 23.8 18.6 34.2 53.5 19.2 26.0 7.6 32.9 10.5 19.4 11.3 11.5 25.5 16.9 34.0 22.3 20.1 20.2 51.6 23.1 34.9 31.6 33.5 9.3 10.4 45.3 28.5 62.3 16.3 11.7 3.2 23.1 30.8 7.1 9.5 38.4 20.6 22.3 9.4 8.9 37.3 34.6 18.1 3.0 31.8 16.7 46.4 18.1 17.9 40.9 29.0 24.7 24.1 5.4 53.8 19.5 22.4 29.9 16.7 47.5 32.7 28.9 30.9 14.6 22.4 26.9 15.5 11.3 18.8 22.7 25.8 17.0 32.8 7.4 13.5 28.9 70.6 77.9 35.6 84.2 79.9 60.4 61.7 55.1 61.5 43.8 58.0 67.9 13.4 3.2 10.1 4.9 13.3 5.7 19.5 12.0 13.1 46.4 11.3 8.8 20.4 17.2 10.4 18.4 8.4 6.2 8.8 9.1 11.7 30.4 0.9 21.2 10.9 17.1 11.5 2.1 14.4 36.5 14.6 22.9 15.8 16.1 10.1 5.1 18.9 9.1 11.8 43.7 13.5 13.8 10.2 11.7 5.7 2.7 16.1 10.3 10.6 3.7 15.0 38.5 16.5 4.5 5.6 28.6 9.3 33.1 19.1 20.8 10.7 15.6 18.2 23.8 19.7 11.1 20.0 4.5 3.9 12.0 9.5 4.2 14.9 5.1 7.9 16.4 SRA1 "SRA, STRAA1" ENSG00000213523 "Steroid receptor RNA activator 1" Q9HD15 5 140537340-140558252 "Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" "Activator, Receptor, Ribonucleoprotein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044598, HPA050153" Approved Supported "Nucleoplasm,Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Microtubules, Cytokinetic bridge, Cytosol" "HPA044598: AB_2679013, HPA050153: AB_2681033" "unprognostic (1.51e-1)" "unprognostic (1.04e-2)" "unprognostic (8.69e-2)" "prognostic favorable (8.01e-6)" "unprognostic (9.32e-2)" "unprognostic (2.56e-1)" "unprognostic (2.90e-1)" "unprognostic (2.43e-1)" "unprognostic (9.38e-2)" "unprognostic (7.41e-2)" "unprognostic (5.58e-3)" "unprognostic (2.61e-1)" "unprognostic (5.34e-2)" "unprognostic (3.10e-2)" "unprognostic (3.01e-2)" "unprognostic (3.71e-1)" "unprognostic (1.04e-1)" 12.2 34.0 8.7 7.7 9.0 9.6 9.7 15.8 12.3 10.0 9.2 12.5 5.1 8.2 6.0 9.3 9.4 5.6 12.0 9.9 9.3 12.4 25.8 15.0 6.3 8.4 8.2 14.9 7.5 4.7 22.2 5.8 8.8 12.5 4.7 7.2 14.8 6.2 14.5 9.4 11.9 5.4 8.6 17.6 14.0 22.6 8.9 5.6 12.9 2.5 5.2 9.4 8.8 9.2 9.7 22.7 11.8 12.3 5.6 7.6 16.4 16.1 9.1 10.3 10.8 41.8 5.9 8.2 11.7 6.2 5.5 6.4 2.1 12.0 4.1 12.7 13.9 7.2 25.0 16.1 12.0 13.1 9.4 14.7 6.1 5.5 2.8 9.1 4.7 13.8 7.4 12.1 6.9 29.5 10.7 20.4 3.6 5.2 18.0 11.7 10.0 7.9 5.4 11.3 8.3 9.8 9.4 8.5 11.6 4.1 10.5 14.7 7.5 9.7 5.1 8.5 13.2 15.1 10.9 8.6 12.0 16.8 6.5 16.1 26.0 20.3 10.7 23.8 9.9 15.8 10.2 10.4 25.2 14.0 8.2 9.4 43.0 13.6 23.6 15.2 19.5 26.8 8.7 9.0 15.8 12.3 9.9 9.3 8.4 8.2 8.8 8.6 8.9 9.2 43.3 6.4 49.4 13.4 46.7 52.4 68.5 126.1 38.7 23.6 57.8 48.9 71.7 57.2 86.4 33.1 8.4 103.7 56.9 87.8 113.5 102.7 104.6 59.5 33.4 39.8 38.4 35.1 15.5 148.2 117.9 48.6 64.7 43.1 68.4 21.8 42.1 69.7 93.1 15.2 17.2 71.6 107.8 61.2 71.5 150.0 25.1 82.0 67.6 7.5 90.4 59.5 42.2 9.0 11.5 186.0 78.7 29.7 113.7 82.9 83.7 131.0 84.1 23.7 26.3 26.7 76.1 77.2 30.7 62.3 45.9 179.0 47.4 66.8 49.2 142.6 SRC "ASV, c-src, SRC1" ENSG00000197122 "SRC proto-oncogene, non-receptor tyrosine kinase" P12931 20 37344685-37406050 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell adhesion, Cell cycle, Host-virus interaction, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 42.0;Gastric mucus-secreting cells: 43.8;Langerhans cells: 46.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 2.4;non-classical monocyte: 2.3" "Group enriched" "Detected in many" 6 "dendritic cells: 1.4;monocytes: 2.4" "Cell line enhanced" "Detected in many" "A549: 110.8;HBEC3-KT: 102.6;RT4: 106.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004023, HPA030875" Approved Supported "Nucleoplasm,Plasma membrane,Cell Junctions,Cytosol" NA NA 3200000 "Cluster 51: Monocytes - Innate immune response" "Cluster 71: Testis - DNA repair" "Cluster 15: RT4 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane, Cell Junctions" "Nucleoplasm, Cytosol" "CAB004023: AB_2106059, HPA030875: AB_2673640" "unprognostic (5.58e-2)" "unprognostic (9.83e-2)" "unprognostic (3.56e-1)" "unprognostic (4.54e-3)" "unprognostic (1.52e-1)" "unprognostic (1.54e-2)" "prognostic unfavorable (4.90e-5)" "unprognostic (3.89e-2)" "unprognostic (7.04e-2)" "unprognostic (8.13e-2)" "unprognostic (1.54e-2)" "prognostic unfavorable (1.63e-4)" "prognostic unfavorable (1.22e-4)" "unprognostic (2.33e-2)" "unprognostic (4.72e-2)" "unprognostic (3.65e-2)" "prognostic favorable (5.22e-5)" 9.7 25.3 5.7 13.3 5.2 8.4 10.1 0.4 6.2 25.1 1.5 30.3 39.8 31.9 3.2 26.1 23.8 27.9 8.8 6.4 5.5 21.4 4.3 16.1 6.3 2.6 3.4 23.6 30.8 11.1 15.9 8.1 2.2 30.8 17.1 5.5 11.8 27.4 2.4 13.0 38.8 17.2 1.7 14.2 39.9 25.2 5.0 6.1 9.8 1.5 8.1 35.6 24.6 3.0 24.6 110.8 24.9 22.6 9.3 14.7 51.6 22.0 18.9 26.3 16.6 41.9 21.5 0.7 13.4 40.2 29.9 43.5 15.1 102.6 10.3 0.1 13.7 6.2 3.9 65.9 22.0 0.3 9.3 15.7 34.2 17.3 22.8 29.4 24.3 14.2 0.6 0.2 4.4 16.7 6.0 0.8 11.7 67.3 98.8 26.5 6.6 0.7 11.0 106.3 23.1 83.6 25.0 34.5 27.2 19.1 31.1 9.0 35.8 31.4 20.9 11.7 20.1 0.3 0.8 0.3 22.1 0.1 24.0 0.0 1.6 0.0 0.0 2.4 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.3 2.3 1.4 0.0 1.0 5.7 5.2 0.4 6.2 6.4 5.5 2.6 3.4 2.2 1.7 5.0 3.0 1.0 3.2 1.7 3.3 4.1 8.2 12.5 9.5 10.8 6.5 6.2 7.5 2.2 18.6 4.7 12.9 2.1 2.3 4.9 42.0 1.9 12.2 1.8 6.4 10.7 1.4 16.8 0.4 9.5 18.7 8.3 7.2 43.8 12.4 0.0 14.8 1.1 1.6 5.7 3.3 9.1 29.2 8.2 9.4 46.3 3.3 10.8 22.8 1.8 9.4 9.7 4.4 1.0 9.0 0.6 39.1 19.2 17.3 4.3 18.0 36.7 9.3 5.6 5.2 13.1 1.8 6.7 0.3 1.1 11.2 9.1 2.3 1.0 2.9 16.9 36.6 STK26 "MASK, MST4" ENSG00000134602 "Serine/threonine kinase 26" Q9P289 X 132023302-132075943 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 70.0;epididymis: 56.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 55.2;dendritic cells: 42.7;NK-cells: 53.5;Syncytiotrophoblasts: 59.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MOLT-4: 140.1;U-937: 144.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA059921 Approved Uncertain "Nucleoplasm,Golgi apparatus,Centrosome,Cytosol" Yes No 360000 "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "Golgi apparatus, Centrosome, Cytosol" "HPA059921: AB_2684163" "unprognostic (6.53e-2)" "unprognostic (7.83e-2)" "unprognostic (1.77e-1)" "unprognostic (1.02e-3)" "unprognostic (4.42e-1)" "unprognostic (1.03e-2)" "prognostic unfavorable (6.82e-4)" "unprognostic (1.18e-1)" "unprognostic (1.93e-1)" "unprognostic (1.31e-1)" "unprognostic (1.42e-3)" "unprognostic (2.49e-1)" "prognostic unfavorable (6.87e-5)" "unprognostic (4.76e-2)" "unprognostic (1.83e-1)" "unprognostic (1.77e-1)" "unprognostic (2.88e-1)" 6.0 2.5 1.0 15.2 2.7 70.0 6.0 1.7 1.3 6.8 2.5 11.5 9.6 46.6 56.3 13.1 7.4 5.6 1.4 0.7 1.5 3.5 5.2 7.2 26.2 0.8 0.8 2.1 3.7 23.5 5.0 25.2 0.7 20.0 11.6 0.2 7.3 35.8 0.9 7.8 6.9 38.1 0.6 13.2 12.2 2.2 3.8 41.3 3.7 1.2 23.5 11.8 7.4 0.7 32.9 11.3 1.3 0.0 5.2 4.9 72.0 1.0 4.0 0.5 0.6 30.1 29.0 44.6 19.4 7.3 22.1 36.5 80.8 51.1 0.0 39.1 66.6 64.6 25.9 28.4 4.7 135.3 5.1 6.9 30.0 0.1 33.7 15.1 14.2 60.0 29.2 40.4 12.2 29.0 140.1 124.9 64.4 22.0 4.3 99.9 39.7 57.9 32.6 51.8 26.6 29.6 19.2 17.0 0.9 54.9 22.0 35.4 0.3 12.8 13.7 39.0 47.9 31.0 52.0 49.8 11.7 144.8 6.5 59.1 9.5 31.6 22.8 12.4 22.4 14.5 15.2 19.6 11.3 12.6 19.7 20.6 18.2 41.0 22.7 4.2 7.2 20.4 1.0 2.7 1.7 1.3 0.7 1.5 0.8 0.8 0.7 0.6 3.8 0.7 0.9 22.4 15.6 0.0 24.7 0.0 36.4 0.0 6.8 0.0 5.9 10.9 1.3 5.7 8.1 11.0 0.0 55.2 42.7 6.5 3.9 4.5 0.6 7.4 1.8 1.7 1.2 12.8 2.0 7.1 34.7 9.6 15.3 17.9 11.4 0.5 1.4 4.4 11.8 0.0 1.4 4.8 0.0 8.8 0.0 0.4 3.4 17.3 0.0 2.8 13.5 0.0 53.5 0.0 0.2 10.9 4.0 2.2 14.5 33.6 1.9 1.5 6.6 0.0 6.6 6.7 3.6 1.8 2.5 16.1 0.0 59.1 27.4 0.6 6.5 18.2 SUMO1 "GMP1, OFC10, PIC1, SMT3C, SMT3H3, SUMO-1, UBL1" ENSG00000116030 "Small ubiquitin like modifier 1" P63165 2 202206182-202238599 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 4 "cerebellum: 7.6" "CAB004269, HPA056956" Supported Supported "Nucleoplasm,Nuclear membrane,Nucleoli,Nuclear bodies" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nuclear membrane" "Nucleoli, Nuclear bodies" "CAB004269: AB_628300, HPA056956: AB_2683285" "unprognostic (7.15e-2)" "unprognostic (2.34e-2)" "unprognostic (1.49e-1)" "unprognostic (2.52e-3)" "unprognostic (2.89e-1)" "unprognostic (9.56e-3)" "unprognostic (1.76e-2)" "unprognostic (8.08e-2)" "unprognostic (1.78e-3)" "prognostic favorable (7.93e-4)" "unprognostic (7.06e-3)" "unprognostic (1.16e-1)" "unprognostic (4.64e-3)" "unprognostic (1.31e-2)" "unprognostic (7.58e-2)" "unprognostic (2.82e-2)" "unprognostic (2.19e-1)" 77.5 99.1 79.4 62.7 84.9 133.7 83.6 89.0 99.9 68.9 84.4 82.7 72.0 65.1 86.3 71.6 65.7 71.7 79.8 85.6 85.3 118.1 174.1 66.5 86.4 79.9 80.1 54.5 55.8 91.6 56.7 75.6 81.1 75.3 82.8 80.2 66.8 61.9 107.5 57.1 80.5 71.5 78.9 68.1 73.8 54.7 81.4 112.1 102.3 103.3 95.4 77.9 54.9 86.6 164.1 82.4 291.4 155.8 159.3 168.5 129.7 171.0 214.6 209.0 274.6 178.1 203.7 111.6 153.5 199.0 193.5 117.1 242.2 237.9 325.0 104.8 185.7 207.6 159.0 211.2 114.9 237.2 188.5 130.9 225.2 164.0 123.9 195.1 197.3 219.0 194.2 176.0 226.4 141.1 298.3 391.6 351.7 168.5 172.2 190.9 163.2 197.9 255.5 134.3 201.7 219.3 140.3 133.6 236.4 313.9 120.0 223.2 139.9 152.5 153.0 141.4 152.8 151.7 322.9 285.8 170.2 165.4 137.2 242.2 220.0 284.2 169.2 226.5 179.6 276.3 206.8 200.0 223.6 231.6 193.8 202.3 256.5 246.5 239.7 187.8 329.0 394.7 79.4 84.9 89.0 99.9 85.6 85.3 79.9 80.1 81.1 78.9 81.4 86.6 182.7 112.2 61.1 10.7 143.1 422.1 204.4 448.6 177.6 99.6 196.8 170.2 58.1 130.1 215.3 189.4 64.6 259.4 162.3 136.6 481.3 250.4 91.3 148.3 115.1 170.7 142.4 140.1 31.4 173.3 297.8 161.8 89.7 115.2 92.6 114.7 142.8 202.1 205.3 87.5 27.8 156.4 319.4 140.7 330.2 28.0 129.8 137.7 211.7 15.9 241.3 182.3 176.1 16.6 21.2 208.1 191.1 127.9 130.5 258.5 272.2 534.4 185.5 87.8 111.7 92.5 221.9 212.0 141.5 183.9 424.5 209.7 174.5 134.9 157.5 254.1 SURF6 "FLJ30322, RRP14" ENSG00000148296 "Surfeit 6" O75683 9 133328776-133336188 "Plasma proteins, Predicted intracellular proteins" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Theca cells: 91.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023608, HPA074622" Approved Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoli, Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "HPA023608: AB_1857671, HPA074622: AB_2686703" "unprognostic (5.27e-3)" "unprognostic (8.67e-3)" "unprognostic (5.41e-3)" "unprognostic (3.69e-2)" "unprognostic (2.61e-1)" "unprognostic (3.20e-1)" "unprognostic (1.26e-3)" "unprognostic (3.60e-2)" "unprognostic (1.18e-1)" "unprognostic (9.37e-2)" "unprognostic (6.18e-3)" "unprognostic (9.32e-3)" "prognostic favorable (7.31e-5)" "unprognostic (1.50e-2)" "unprognostic (1.86e-1)" "unprognostic (2.06e-1)" "unprognostic (2.66e-1)" 10.4 11.7 8.1 4.1 7.8 4.9 10.3 8.7 7.5 12.4 5.9 13.6 6.2 11.9 2.6 12.5 11.2 2.5 10.5 7.2 7.5 11.7 12.3 8.5 5.5 7.7 7.8 13.1 11.2 3.9 8.1 3.3 7.8 11.5 3.4 3.3 9.7 4.0 17.9 13.2 12.1 2.7 7.5 11.4 9.9 7.9 7.9 4.6 10.6 3.9 3.7 12.2 11.1 8.1 5.6 8.7 6.5 9.8 4.0 3.7 10.8 8.8 5.1 7.7 4.8 13.8 9.2 16.2 6.7 4.9 5.6 16.7 8.4 9.3 2.8 10.8 9.6 11.2 10.5 8.3 7.2 19.1 9.3 5.3 8.0 8.0 7.4 6.8 4.0 15.6 25.1 8.4 6.8 14.7 15.5 15.7 19.1 22.7 15.6 16.1 9.1 16.7 6.7 5.3 13.7 11.6 8.6 13.7 7.8 3.9 12.2 10.6 8.4 17.3 9.3 8.9 12.0 6.2 9.6 21.0 6.5 12.9 10.4 3.3 3.0 1.4 4.3 2.9 4.5 4.6 3.9 3.9 3.3 5.1 5.2 4.4 0.8 3.2 2.7 6.0 3.6 2.5 8.1 7.8 8.7 7.5 7.2 7.5 7.7 7.8 7.8 7.5 7.9 8.1 25.7 44.8 27.3 4.6 20.9 23.7 15.7 11.0 24.5 26.5 33.4 32.3 30.0 28.6 24.5 22.0 6.2 32.2 20.3 36.8 21.5 29.2 1.3 21.1 42.2 23.6 33.6 14.1 4.3 19.6 25.2 21.2 18.8 25.1 25.3 25.4 16.4 35.2 21.2 21.9 4.8 40.3 6.1 14.7 10.2 4.1 27.7 13.7 7.2 5.6 18.6 15.2 29.9 5.0 4.1 29.0 33.3 27.8 14.4 24.8 50.6 26.1 13.2 19.6 0.0 15.8 20.3 19.2 23.6 26.3 27.6 19.0 18.1 91.1 57.7 13.3 SUZ12 "CHET9, JJAZ1, KIAA0160" ENSG00000178691 "SUZ12 polycomb repressive complex 2 subunit" Q15022 17 31937007-32001038 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Cancer-related genes, Disease variant, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057436 Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Nuclear bodies" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nucleoli, Nucleoli rim, Nuclear bodies" "HPA057436: AB_2683439" "unprognostic (1.23e-1)" "unprognostic (1.11e-1)" "unprognostic (3.65e-3)" "unprognostic (1.23e-1)" "unprognostic (2.49e-1)" "unprognostic (7.31e-2)" "unprognostic (2.66e-3)" "unprognostic (8.05e-2)" "unprognostic (7.27e-2)" "unprognostic (3.06e-2)" "unprognostic (6.29e-2)" "unprognostic (8.70e-2)" "unprognostic (3.28e-2)" "unprognostic (2.25e-1)" "unprognostic (1.28e-1)" "unprognostic (5.91e-2)" "unprognostic (1.31e-1)" 12.3 11.8 6.3 18.8 6.3 45.4 15.0 11.1 8.5 11.6 6.8 14.9 16.0 15.2 12.0 14.0 11.0 12.0 10.3 5.4 5.8 16.4 18.1 12.6 33.0 5.4 5.9 11.4 11.5 19.8 6.6 18.7 5.6 13.3 16.4 26.5 10.5 12.2 8.1 13.0 15.3 14.7 5.2 18.4 15.2 27.4 6.1 38.5 18.3 11.0 30.0 15.6 9.0 7.1 46.5 40.4 37.2 42.9 21.1 26.8 38.2 44.2 38.8 53.0 63.7 30.9 25.5 100.7 33.2 27.7 45.4 40.1 56.0 25.5 85.7 35.8 54.0 69.9 32.9 22.3 24.8 111.5 68.7 18.7 28.1 53.1 40.4 32.1 33.1 47.3 68.8 135.6 46.2 16.2 133.3 64.4 21.3 32.4 24.4 78.5 95.3 81.9 31.1 44.6 47.5 37.1 71.3 22.7 43.3 25.8 66.0 91.5 24.7 41.9 38.0 50.8 69.3 73.5 98.4 122.5 30.7 67.4 38.7 0.6 0.7 1.6 1.4 1.1 1.1 2.4 1.6 1.6 0.6 1.8 1.5 2.1 1.6 1.8 0.7 1.9 1.8 0.4 6.3 6.3 11.1 8.5 5.4 5.8 5.4 5.9 5.6 5.2 6.1 7.1 44.5 41.7 45.8 43.1 50.1 58.5 50.2 21.8 31.9 77.6 54.2 36.8 32.3 27.1 32.6 35.0 108.4 61.5 65.2 24.0 17.6 28.3 16.2 52.8 55.8 45.1 29.4 93.6 71.6 21.9 53.1 35.1 31.1 54.2 15.8 41.4 38.2 42.3 32.9 62.2 69.5 31.8 10.2 42.1 58.2 13.9 26.8 47.3 24.9 45.0 73.1 45.7 38.1 75.4 71.3 27.8 15.4 25.6 66.2 62.8 21.5 26.6 29.6 80.9 13.1 47.2 38.4 121.7 128.9 48.6 71.7 69.5 52.5 52.8 35.6 66.7 TAF1D "JOSD3, MGC5306, TAF(I)41" ENSG00000166012 "TATA-box binding protein associated factor, RNA polymerase I subunit D" Q9H5J8 11 93729948-93784391 "Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030703, HPA055935, HPA060385" Uncertain Supported "Nucleoplasm,Nucleoli,Mitotic spindle,Centriolar satellite" Yes No "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Nucleoli, Mitotic spindle, Centriolar satellite" "HPA030703: , HPA055935: AB_2682974, HPA060385: AB_2684271" "unprognostic (9.91e-3)" "unprognostic (4.38e-2)" "unprognostic (6.80e-2)" "unprognostic (1.71e-1)" "unprognostic (5.40e-3)" "unprognostic (6.46e-2)" "unprognostic (3.68e-3)" "unprognostic (9.70e-2)" "unprognostic (5.24e-3)" "unprognostic (3.55e-2)" "unprognostic (4.50e-3)" "unprognostic (1.09e-2)" "prognostic unfavorable (3.17e-7)" "unprognostic (1.95e-1)" "unprognostic (2.51e-1)" "unprognostic (2.34e-1)" "unprognostic (6.37e-2)" 10.0 9.3 2.5 18.2 3.0 16.4 12.6 5.0 6.7 7.7 1.2 9.5 13.7 14.1 9.0 9.5 7.7 15.4 7.1 2.9 3.5 6.8 6.9 8.1 20.6 2.3 0.6 13.8 20.9 5.3 4.9 18.0 2.3 9.9 12.5 8.2 10.1 7.3 8.0 11.4 13.3 9.1 0.5 11.9 11.9 5.5 1.7 10.9 10.1 7.1 13.1 13.8 7.2 7.8 18.2 8.6 17.5 17.9 14.0 47.8 29.2 27.0 11.5 18.4 13.8 28.6 38.8 32.6 34.0 15.6 12.6 44.3 21.5 25.9 21.2 10.6 7.8 34.8 55.6 20.2 16.4 31.9 25.1 19.5 25.8 16.0 35.7 35.0 23.7 22.7 24.2 50.4 22.8 5.0 25.8 66.4 12.1 16.7 9.6 23.3 19.1 30.9 22.7 17.4 10.7 19.5 10.8 38.2 16.5 19.3 32.7 12.4 28.7 26.9 30.5 44.2 28.7 22.9 26.2 32.5 11.2 36.9 10.3 44.2 16.7 28.8 17.3 12.5 17.7 39.1 24.9 19.8 12.0 39.8 28.4 24.1 42.7 18.1 10.8 26.1 18.2 5.2 2.5 3.0 5.0 6.7 2.9 3.5 2.3 0.6 2.3 0.5 1.7 7.8 106.7 89.8 95.5 20.9 246.1 244.2 252.4 66.6 255.0 86.6 129.4 130.9 26.2 134.4 105.3 29.5 39.6 176.0 162.5 94.5 45.0 95.2 19.9 144.9 184.9 121.3 110.2 98.4 41.6 146.3 170.2 147.1 125.4 245.6 104.4 257.2 63.1 54.2 69.3 69.0 38.2 148.0 24.4 103.7 153.6 16.5 128.6 112.0 80.0 24.4 102.1 34.8 89.6 35.2 44.0 110.4 87.5 67.7 162.2 269.2 71.1 101.5 67.7 78.2 72.3 187.4 123.1 49.0 71.5 251.4 203.0 160.9 182.3 119.7 174.1 356.8 TCTN1 "FLJ21127, JBTS13, TECT1" ENSG00000204852 "Tectonic family member 1" Q2MV58 12 110614027-110663431 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein" "Ciliopathy, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 98.9;Respiratory ciliated cells: 203.7;Spermatocytes: 96.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 34.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039687, HPA040036" Approved Approved "Nucleoplasm,Vesicles,Actin filaments,Microtubules" "Intracellular and membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Actin filaments" "Nucleoplasm, Vesicles, Microtubules" "HPA039687: AB_10795293, HPA040036: AB_10794759" "unprognostic (2.54e-1)" "unprognostic (7.22e-3)" "unprognostic (2.28e-1)" "prognostic favorable (1.13e-5)" "unprognostic (2.89e-2)" "unprognostic (6.53e-2)" "unprognostic (2.11e-1)" "unprognostic (3.05e-2)" "unprognostic (6.02e-2)" "unprognostic (4.54e-2)" "unprognostic (5.20e-3)" "unprognostic (9.60e-2)" "unprognostic (9.97e-2)" "unprognostic (2.15e-2)" "unprognostic (8.41e-2)" "unprognostic (1.24e-1)" "unprognostic (4.27e-2)" 8.8 14.0 5.6 2.0 5.3 1.0 8.4 9.3 7.5 10.1 18.2 7.1 1.5 9.0 10.7 4.5 15.3 5.6 17.0 5.7 4.5 19.0 9.1 8.3 2.5 4.5 5.0 12.8 10.8 15.2 26.2 4.0 4.4 10.0 0.9 3.0 9.5 6.1 10.3 5.3 4.0 3.6 3.6 4.6 6.9 21.1 5.2 1.3 17.6 1.9 0.8 7.7 7.0 7.0 11.6 11.7 6.7 17.6 24.9 18.0 4.3 6.3 16.2 5.9 4.4 1.2 2.7 2.0 6.9 18.6 7.2 6.1 4.7 4.6 5.0 4.7 8.7 0.3 4.1 3.6 8.6 1.2 1.3 14.8 7.8 7.7 7.9 34.7 3.3 3.0 7.4 2.5 9.7 9.4 0.9 2.2 4.1 3.5 16.7 2.4 2.9 14.6 16.8 1.8 5.5 11.7 13.1 1.6 5.3 5.5 22.7 16.0 4.0 8.2 2.4 3.5 6.0 4.2 2.6 2.6 11.1 1.3 9.3 0.0 2.0 0.0 0.8 3.6 2.2 4.9 1.5 2.5 3.4 9.1 2.2 1.6 6.4 1.0 1.9 4.3 0.5 2.0 5.6 5.3 9.3 7.5 5.7 4.5 4.5 5.0 4.4 3.6 5.2 7.0 6.5 3.2 18.8 25.5 24.0 13.8 28.4 38.4 18.2 10.7 22.8 19.3 13.0 24.3 26.0 16.5 31.3 30.9 5.8 1.0 9.8 24.3 82.7 98.9 29.0 11.5 18.0 1.3 15.0 4.7 8.5 30.5 8.2 9.8 3.8 27.1 9.3 6.9 11.8 3.3 12.1 4.8 32.6 3.8 12.4 18.7 17.1 7.0 23.2 7.5 1.7 30.5 0.0 12.5 9.3 4.2 2.4 28.6 9.6 20.0 0.4 42.5 203.7 34.1 6.6 16.2 18.3 96.9 30.1 8.5 11.2 18.3 4.2 38.1 4.7 16.6 TIAM1 ENSG00000156299 "TIAM Rac1 associated GEF 1" Q13009 21 31118416-31559977 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 207.9" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 327.3;Microglial cells: 133.0;Oligodendrocyte precursor cells: 120.6;Oligodendrocytes: 124.6;Suprabasal keratinocytes: 143.3" "Cancer enhanced" "Detected in many" "testis cancer: 15.1" "Region enriched" "Detected in all" 4 "cerebellum: 207.9" "Group enriched" "Detected in many" 5 "classical monocyte: 17.4;intermediate monocyte: 15.3;memory CD4 T-cell: 12.5;myeloid DC: 9.6;naive CD4 T-cell: 16.2;NK-cell: 11.3;non-classical monocyte: 22.0;T-reg: 27.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 34.5;HEL: 34.7;HMC-1: 29.1;RT4: 35.5;SCLC-21H: 32.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 245.9" "CAB010416, HPA034853" Enhanced Supported "Nucleoplasm,Nuclear membrane,Cell Junctions,Cytokinetic bridge,Cytosol" Yes NA "Cluster 27: Non-specific - Gene expression" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cell Junctions" "Nuclear membrane, Cytokinetic bridge, Cytosol" "CAB010416: AB_2240410, HPA034853: " "unprognostic (9.59e-2)" "unprognostic (7.44e-3)" "unprognostic (5.64e-3)" "unprognostic (1.07e-1)" "unprognostic (1.58e-1)" "unprognostic (2.81e-3)" "unprognostic (2.84e-2)" "unprognostic (3.73e-1)" "unprognostic (8.08e-2)" "unprognostic (2.70e-3)" "unprognostic (7.97e-3)" "unprognostic (9.52e-2)" "unprognostic (1.20e-3)" "unprognostic (2.38e-3)" "unprognostic (1.61e-1)" "unprognostic (1.04e-2)" "unprognostic (2.21e-1)" 7.2 12.7 40.3 6.6 35.2 2.8 5.4 207.9 49.2 17.8 12.5 5.1 1.7 9.9 3.2 39.7 11.0 4.6 5.5 51.8 26.5 5.5 7.9 5.8 11.1 26.7 33.4 3.3 2.2 0.3 12.9 4.3 36.1 9.0 3.1 8.6 5.6 3.3 0.9 27.2 5.0 11.1 27.5 5.2 2.4 10.5 37.3 18.7 1.9 0.8 11.1 12.1 18.5 28.6 2.9 1.0 21.7 1.3 0.4 4.9 34.5 0.0 0.0 2.7 0.9 0.2 3.9 7.6 1.5 0.5 4.0 5.1 2.5 4.4 4.3 0.6 12.0 34.7 0.7 0.2 0.5 0.0 29.1 2.2 1.5 14.7 5.9 2.6 0.0 11.3 0.0 10.9 11.1 14.7 5.4 0.2 7.1 5.3 9.4 7.0 6.8 0.0 3.3 35.5 32.6 8.1 1.5 11.4 1.3 7.5 4.7 0.1 0.2 3.1 12.5 0.0 1.5 12.3 9.9 6.6 7.2 2.6 24.2 1.5 17.4 0.0 0.5 15.3 3.1 0.1 12.5 2.4 9.6 0.0 16.2 1.0 1.0 11.3 22.0 0.5 27.8 5.9 40.3 35.2 207.9 49.2 51.8 26.5 26.7 33.4 36.1 27.5 37.3 28.6 3.7 3.2 2.3 21.2 1.7 83.7 65.6 3.0 22.8 8.9 4.9 1.9 1.1 1.5 11.8 0.0 2.1 10.1 8.0 1.3 0.0 1.8 11.7 25.2 2.2 31.4 5.4 2.7 43.9 0.7 29.7 11.4 2.0 28.4 24.1 2.0 35.0 5.5 8.1 74.0 327.3 0.4 10.2 22.9 73.4 11.3 34.5 26.3 10.6 133.0 37.3 35.2 4.1 120.6 124.6 1.8 11.6 58.3 3.2 30.8 0.0 0.5 1.2 4.6 6.6 0.9 2.1 1.3 9.8 60.2 143.3 10.7 16.3 82.6 1.2 106.7 TIGD1 EEYORE ENSG00000221944 "Tigger transposable element derived 1" Q96MW7 2 232543883-232550557 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041717 Approved Approved "Nucleoplasm,Nucleoli rim,Nuclear bodies,Mitotic chromosome" Yes No "Cluster 32: T-cells - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 24: NB-4 - Immune response" "Cluster 52: Non-specific - Transcription" "Nucleoli rim, Mitotic chromosome" "Nucleoplasm, Nuclear bodies" "HPA041717: AB_2677636" "unprognostic (2.48e-1)" "unprognostic (1.77e-2)" "unprognostic (2.10e-2)" "unprognostic (1.86e-1)" "unprognostic (2.58e-2)" "unprognostic (2.81e-1)" "unprognostic (1.62e-2)" "unprognostic (1.24e-1)" "unprognostic (1.21e-2)" "unprognostic (1.20e-2)" "unprognostic (4.40e-2)" "unprognostic (6.86e-2)" "prognostic unfavorable (4.41e-5)" "unprognostic (3.77e-2)" "unprognostic (1.85e-2)" "unprognostic (2.77e-1)" "unprognostic (3.21e-3)" 1.8 2.3 6.3 2.3 5.3 6.5 2.7 13.4 7.8 3.2 5.4 2.8 1.9 2.6 2.9 2.8 3.8 1.9 2.4 5.0 4.5 7.4 2.7 2.5 3.4 3.2 2.4 5.7 2.9 1.6 5.0 2.0 4.1 4.4 2.1 10.4 2.7 1.7 4.0 4.2 3.6 1.3 1.5 6.1 3.3 5.2 4.5 3.3 4.7 1.4 2.2 2.8 3.0 9.7 3.1 2.3 4.7 7.5 1.7 2.3 3.6 2.1 1.2 2.6 2.9 2.8 3.6 5.0 1.5 1.6 2.8 3.2 4.1 1.3 3.8 3.0 3.9 4.5 7.7 3.5 1.1 3.6 2.9 2.6 1.2 2.6 1.6 2.5 1.5 6.5 3.6 5.0 2.1 5.3 4.9 8.3 2.8 1.9 2.7 4.7 6.3 2.3 1.5 3.5 6.1 6.0 2.2 2.1 2.3 3.3 3.1 3.9 2.5 4.3 4.5 2.7 2.1 4.8 3.4 4.5 2.5 3.6 2.6 1.6 1.7 1.8 1.9 1.4 1.9 1.7 2.0 1.5 1.1 2.1 3.1 2.5 2.3 1.8 1.5 1.2 1.6 0.7 6.3 5.3 13.4 7.8 5.0 4.5 3.2 2.4 4.1 1.5 4.5 9.7 2.4 9.6 3.9 4.2 5.3 1.3 4.5 2.3 1.8 4.9 2.5 2.2 2.0 1.5 2.9 3.7 8.4 2.2 3.1 1.7 0.0 3.6 4.2 1.0 3.6 1.7 1.2 6.5 4.5 1.5 1.3 3.1 7.7 1.5 0.0 6.4 1.4 0.7 1.4 6.7 5.7 1.5 2.0 1.6 1.7 0.7 4.7 2.4 1.8 1.0 2.8 7.5 5.2 5.0 8.1 2.0 2.4 1.9 5.6 2.6 3.5 1.4 1.7 7.0 6.6 3.7 2.0 3.9 5.7 3.7 2.0 1.4 4.1 4.0 3.0 2.9 TMA7 "CCDC72, HSPC016" ENSG00000232112 "Translation machinery associated 7 homolog" Q9Y2S6 3 48440257-48444208 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047397 Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Nuclear bodies" Yes No "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Nucleoli rim" "Nucleoplasm, Nuclear bodies" "HPA047397: AB_2680029" "unprognostic (1.26e-3)" "unprognostic (1.21e-1)" "unprognostic (9.10e-2)" "unprognostic (1.18e-2)" "unprognostic (2.06e-1)" "unprognostic (5.02e-2)" "unprognostic (3.55e-2)" "prognostic favorable (8.33e-4)" "unprognostic (1.14e-2)" "unprognostic (3.85e-3)" "unprognostic (1.92e-2)" "unprognostic (2.55e-2)" "unprognostic (1.14e-2)" "unprognostic (9.31e-3)" "unprognostic (3.13e-2)" "unprognostic (1.14e-1)" "unprognostic (8.64e-3)" 252.5 276.8 498.7 220.7 507.8 434.6 241.9 504.6 588.9 236.5 500.2 253.3 192.8 179.4 344.5 310.5 181.7 117.9 355.4 502.2 514.7 317.6 273.2 208.0 279.3 511.7 510.0 259.6 230.3 309.8 302.0 146.6 505.9 239.6 229.3 295.4 215.9 142.7 511.6 215.1 220.4 132.7 513.0 272.9 235.5 216.0 511.9 388.3 232.4 287.4 297.7 213.3 239.3 514.5 565.0 398.8 634.2 456.6 514.0 497.1 435.6 454.1 355.7 425.1 419.3 326.3 395.9 365.2 315.3 397.8 553.6 215.5 559.8 512.5 471.6 452.6 475.5 689.4 910.3 845.8 399.0 792.2 443.0 459.7 538.2 402.6 388.8 414.2 546.0 641.1 376.6 379.0 615.3 581.2 929.4 1071.2 847.1 607.0 637.3 262.2 397.0 620.4 746.0 748.7 207.8 526.1 511.0 369.3 736.1 583.6 356.7 1156.3 412.1 358.0 650.8 560.5 902.6 626.1 1001.6 902.8 459.1 754.2 379.9 1923.2 1058.7 2195.0 1127.1 1022.5 1237.6 1412.6 1486.0 1377.1 1150.8 1172.2 1464.7 1408.1 2036.5 943.8 1028.9 1521.6 1652.1 2663.7 498.7 507.8 504.6 588.9 502.2 514.7 511.7 510.0 505.9 513.0 511.9 514.5 518.8 240.4 370.4 20.9 615.0 716.3 534.0 1308.9 618.6 219.6 866.8 1111.2 633.4 513.3 616.2 901.2 106.3 785.4 797.4 948.2 1717.8 566.9 653.6 524.8 511.4 474.5 635.3 609.1 25.8 1032.9 830.9 443.7 356.3 646.1 454.4 376.5 574.7 1098.6 854.5 119.5 25.4 985.5 695.8 652.4 790.5 1123.9 646.8 544.3 777.3 18.7 850.3 522.8 1080.3 10.1 28.3 872.9 980.3 464.6 593.9 584.6 1211.0 1438.8 466.4 321.9 355.0 393.6 448.4 547.4 689.4 805.5 898.4 440.1 757.1 351.9 937.2 572.2 TMEM132E DFNB99 ENSG00000181291 "Transmembrane protein 132E" Q6IEE7 17 34579487-34639318 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 17.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 4.1;Inhibitory neurons: 6.4;Oligodendrocyte precursor cells: 13.0;Proximal tubular cells: 11.5" "Cancer enriched" "Detected in some" 4 "glioma: 7.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "RPMI-8226: 37.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070608 Approved Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus,Cytosol" NA NA 170000 "Cluster 40: NK-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Golgi apparatus" "Nuclear bodies, Cytosol" "HPA070608: AB_2686286" "unprognostic (1.92e-1)" "unprognostic (1.68e-1)" "unprognostic (3.29e-5)" "unprognostic (3.37e-1)" "unprognostic (1.37e-1)" "unprognostic (8.61e-2)" "unprognostic (1.06e-3)" "unprognostic (1.72e-1)" "unprognostic (1.80e-1)" "unprognostic (1.56e-2)" "unprognostic (2.16e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.55e-4)" "unprognostic (1.67e-2)" "unprognostic (1.51e-2)" "unprognostic (2.65e-1)" "unprognostic (8.71e-2)" 0.3 0.1 4.6 0.0 3.0 0.0 0.1 6.1 6.4 0.4 0.0 0.1 1.2 0.1 0.0 0.1 0.1 0.1 0.5 2.6 6.2 3.6 0.4 0.1 0.1 17.9 5.1 0.2 0.0 0.0 0.1 0.1 10.2 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.7 0.1 8.7 0.3 0.1 1.9 6.5 0.0 0.2 0.0 0.1 0.1 0.2 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.1 4.3 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.2 0.0 0.0 0.0 0.0 4.6 3.0 6.1 6.4 2.6 6.2 17.9 5.1 10.2 8.7 6.5 11.1 0.1 0.0 0.0 2.6 0.1 0.3 0.0 0.0 0.0 1.9 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.1 0.0 0.0 4.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 6.4 0.0 0.0 1.9 0.7 2.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 13.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 11.5 0.0 0.1 0.0 0.2 0.5 1.2 2.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 TMEM62 FLJ23375 ENSG00000137842 "Transmembrane protein 62" Q0P6H9 15 43123279-43185144 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "OE19: 61.0;U-266/84: 67.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044461, HPA062359" Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Nuclear bodies,Cytoplasmic bodies" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 16: U-266 - Nucleosome" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Nucleoli fibrillar center, Nuclear bodies, Cytoplasmic bodies" "HPA044461: AB_2678950, HPA062359: AB_2684747" "unprognostic (7.43e-2)" "unprognostic (4.96e-2)" "unprognostic (4.56e-2)" "prognostic favorable (9.72e-7)" "unprognostic (2.53e-1)" "unprognostic (1.98e-1)" "unprognostic (2.39e-2)" "unprognostic (1.41e-2)" "unprognostic (4.83e-2)" "unprognostic (3.30e-1)" "unprognostic (3.90e-2)" "unprognostic (1.77e-1)" "unprognostic (8.61e-2)" "unprognostic (1.20e-1)" "unprognostic (6.48e-2)" "unprognostic (1.20e-1)" "unprognostic (6.67e-2)" 7.1 4.6 4.8 6.0 5.0 9.0 22.9 8.2 6.7 8.1 3.6 13.1 13.1 5.4 12.3 6.2 7.5 7.9 5.1 5.3 4.8 7.6 10.3 8.8 7.2 4.5 4.5 3.2 8.1 13.7 4.6 10.3 5.0 6.1 14.4 8.9 13.6 7.1 9.4 5.2 11.7 6.5 5.0 6.1 10.2 2.0 5.4 4.0 8.5 6.6 8.0 7.6 5.4 5.6 14.9 7.9 3.5 6.8 4.3 5.5 36.4 13.9 17.6 24.1 33.3 12.5 28.5 15.0 7.9 13.2 21.7 27.6 14.8 10.9 8.7 17.7 6.8 12.2 15.4 9.5 9.4 12.7 10.5 3.9 13.0 10.6 7.4 6.8 13.6 3.7 10.9 12.7 2.8 3.5 0.0 3.0 1.2 61.0 3.2 7.5 3.7 7.9 12.9 18.6 22.2 9.6 10.9 27.2 6.7 3.9 14.6 12.9 8.0 11.9 4.9 8.5 22.7 10.6 67.1 10.7 11.0 14.0 10.4 0.5 0.7 1.1 0.8 0.3 1.0 0.7 1.1 1.0 0.7 0.8 0.7 0.9 0.2 1.6 0.4 1.7 2.0 0.4 4.8 5.0 8.2 6.7 5.3 4.8 4.5 4.5 5.0 5.0 5.4 5.6 7.7 16.0 4.6 12.1 18.8 2.3 4.1 2.8 5.7 5.6 12.3 6.3 2.6 8.6 5.0 12.9 10.4 21.9 7.0 12.5 5.9 12.9 1.6 9.6 3.7 5.6 4.2 9.1 36.3 14.8 25.2 4.8 11.2 13.9 5.1 7.0 6.1 7.3 7.5 1.7 33.4 11.4 6.1 6.5 4.8 3.7 2.5 7.1 5.4 18.7 6.4 7.8 6.2 29.1 34.5 12.2 8.1 1.2 16.5 2.7 12.8 3.4 6.1 9.9 6.6 4.1 5.2 2.2 1.0 8.6 2.8 34.1 7.4 3.8 11.0 4.8 TNFAIP2 "B94, EXOC3L3" ENSG00000185215 "TNF alpha induced protein 2" Q03169 14 103121476-103137439 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Angiogenesis, Differentiation" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "urinary bladder: 277.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 295.5;Langerhans cells: 198.7;monocytes: 351.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 48.4" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 5 "RT4: 785.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB004598, HPA030624" Enhanced Approved "Nucleoplasm,Nuclear membrane,Golgi apparatus,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus, Cytosol" "Nucleoplasm, Nuclear membrane" "CAB004598: AB_628370, HPA030624: AB_2673552" "unprognostic (5.01e-3)" "unprognostic (4.93e-2)" "unprognostic (1.56e-3)" "unprognostic (8.02e-3)" "unprognostic (3.39e-2)" "unprognostic (2.98e-2)" "unprognostic (5.52e-3)" "unprognostic (5.97e-2)" "unprognostic (1.94e-1)" "unprognostic (7.02e-2)" "unprognostic (1.22e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (4.10e-4)" "prognostic favorable (2.79e-5)" "unprognostic (1.75e-2)" "unprognostic (3.83e-2)" "prognostic favorable (7.17e-5)" 119.9 76.8 9.0 103.6 11.5 106.8 78.4 6.7 12.2 53.8 12.1 39.8 38.0 50.9 6.6 88.3 57.1 102.2 48.3 8.0 9.7 67.7 61.6 142.4 87.4 17.1 10.4 16.9 33.6 66.8 16.6 48.4 16.2 73.6 26.8 1.6 84.0 14.9 35.0 53.3 52.5 24.8 13.6 147.9 37.4 37.1 21.4 39.5 36.8 32.5 80.3 277.5 74.6 16.1 34.7 156.3 1.1 0.6 10.1 45.9 54.5 9.7 43.2 26.4 8.9 1.6 148.7 0.3 120.3 48.5 142.5 104.2 11.6 0.0 11.9 6.1 0.6 15.4 120.0 0.7 19.2 7.7 20.0 17.8 1.6 8.4 0.1 10.5 14.2 7.7 15.5 35.3 3.6 3.4 0.4 11.6 9.7 19.6 13.4 6.8 18.9 24.9 80.8 785.1 1.3 2.3 150.2 52.4 1.9 5.6 83.8 50.4 28.4 5.1 13.5 30.3 31.5 31.4 2.4 0.9 38.1 34.0 16.1 5.9 16.8 9.0 0.1 18.6 0.1 0.1 0.1 0.0 9.4 0.2 0.1 0.1 48.4 0.2 15.0 0.5 0.0 4.5 9.0 11.5 6.7 12.2 8.0 9.7 17.1 10.4 16.2 13.6 21.4 16.1 45.8 0.0 25.1 2.3 8.2 28.3 41.8 295.5 6.8 1.1 24.2 11.4 14.1 51.5 126.1 27.6 0.0 1.2 1.3 1.0 0.0 160.9 36.8 92.4 122.2 47.1 17.3 1.7 2.5 44.7 61.2 123.3 5.6 172.8 33.7 4.5 18.9 8.0 54.1 0.0 5.7 0.3 85.5 151.2 198.7 48.8 8.4 163.3 30.2 25.3 351.9 5.9 5.2 1.0 0.9 122.1 18.3 2.2 11.7 186.0 0.7 14.4 121.5 0.7 19.7 104.9 39.7 2.1 4.6 20.7 33.4 4.8 8.3 1.1 1.9 138.6 TNFRSF25 "APO-3, DDR3, DR3, LARD, TNFRSF12, TR3, TRAMP, WSL-1, WSL-LR" ENSG00000215788 "TNF receptor superfamily member 25" Q93038 1 6460786-6466175 "Predicted membrane proteins, Predicted secreted proteins" Apoptosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 44.0;pituitary gland: 29.9;skin 1: 25.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 34.1;Excitatory neurons: 37.5;T-cells: 41.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "MAIT T-cell: 5.6;memory CD4 T-cell: 4.4;memory CD8 T-cell: 2.2;naive CD4 T-cell: 4.4;T-reg: 7.9" "Lineage enriched" "Detected in many" 7 "T-cells: 7.9" "Cell line enhanced" "Detected in many" "HDLM-2: 20.5;RPMI-8226: 25.7" "Group enriched" "Detected in some" 6 "amygdala: 1.2;cerebral cortex: 1.4;hippocampal formation: 2.0" "Not detected" "Not detected" HPA069834 Approved "Nucleoplasm,Plasma membrane,Actin filaments,Focal adhesion sites" "Secreted - unknown location" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Actin filaments, Focal adhesion sites" Nucleoplasm "HPA069834: " "unprognostic (8.09e-3)" "unprognostic (6.91e-3)" "prognostic unfavorable (4.46e-4)" "unprognostic (1.97e-1)" "unprognostic (9.63e-3)" "prognostic favorable (3.09e-4)" "unprognostic (2.16e-1)" "unprognostic (1.46e-1)" "unprognostic (2.04e-1)" "unprognostic (2.07e-1)" "unprognostic (6.01e-2)" "unprognostic (3.98e-2)" "prognostic unfavorable (1.65e-7)" "unprognostic (1.21e-1)" "unprognostic (1.61e-1)" "unprognostic (3.44e-1)" "unprognostic (8.68e-3)" 6.4 4.2 4.0 3.2 4.0 0.8 4.0 11.1 6.1 5.2 4.9 6.1 3.0 3.0 0.6 10.3 5.7 2.2 8.7 4.8 4.3 3.3 1.2 2.4 4.3 3.7 3.6 3.1 1.5 0.9 29.9 4.4 4.4 5.2 1.4 1.2 3.3 2.3 1.1 25.3 5.0 0.5 3.3 44.0 2.0 0.9 3.7 2.0 3.2 1.2 2.7 2.5 4.6 3.5 1.8 0.4 1.1 2.0 0.0 0.6 1.3 1.5 0.6 0.3 0.0 1.7 2.8 0.0 2.5 0.0 1.3 4.2 0.6 4.7 0.0 20.5 1.5 0.6 1.7 0.1 0.7 0.0 0.1 0.0 3.2 1.5 4.1 2.7 4.0 1.1 0.0 0.0 0.0 2.2 0.0 8.0 1.4 1.4 3.4 0.6 0.3 25.7 1.3 0.7 3.4 5.3 0.0 2.5 0.1 0.6 2.0 2.9 2.5 1.3 2.1 0.0 2.0 0.0 3.5 0.0 2.4 0.0 0.0 0.0 0.0 0.0 1.0 0.2 5.6 0.0 4.4 2.2 0.5 0.0 4.4 0.7 0.0 0.8 1.0 0.0 7.9 0.9 4.0 4.0 11.1 6.1 4.8 4.3 3.7 3.6 4.4 3.3 3.7 3.5 19.0 3.2 5.0 3.9 2.5 24.6 2.3 5.6 11.4 3.1 4.2 5.5 1.1 1.5 3.3 1.8 2.1 0.7 12.8 34.1 0.0 0.2 0.2 4.1 11.2 11.5 6.7 3.0 37.5 0.4 2.0 2.3 5.6 6.9 7.0 4.8 7.9 1.1 4.0 5.0 21.6 20.3 0.0 1.2 6.6 0.3 2.8 4.0 7.2 14.0 3.0 10.2 10.3 7.5 2.1 1.4 16.0 9.4 3.2 3.7 9.8 0.6 4.8 9.1 0.0 2.6 2.6 0.4 1.2 8.6 28.6 0.1 41.4 0.7 25.0 6.8 TNNT2 "CMD1D, CMH2, CMPD2" ENSG00000118194 "Troponin T2, cardiac type" P45379 1 201359008-201377764 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Muscle protein" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 205 "heart muscle: 10670.6" "Cell type enriched" "Detected in many" 32 "Cardiomyocytes: 12561.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 18 "RH-30: 1077.7" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebral cortex: 3.8" "CAB015371, HPA015774, HPA017888" Enhanced Approved "Nucleoplasm,Nucleoli,Focal adhesion sites,Microtubules" No No 57000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Nucleoli" "Focal adhesion sites, Microtubules" "CAB015371: AB_630390, HPA015774: AB_1858354, HPA017888: AB_1858355" "unprognostic (1.45e-1)" "unprognostic (2.74e-1)" "unprognostic (2.33e-4)" "unprognostic (1.85e-1)" "unprognostic (7.29e-2)" "unprognostic (1.79e-1)" "unprognostic (1.80e-1)" "unprognostic (1.24e-1)" "unprognostic (1.42e-1)" "unprognostic (2.91e-2)" "unprognostic (1.38e-1)" "unprognostic (8.63e-2)" "unprognostic (5.50e-3)" "unprognostic (2.94e-1)" "unprognostic (1.61e-1)" "unprognostic (4.76e-2)" "unprognostic (9.98e-2)" 2.2 4.9 12.4 0.6 13.9 0.1 11.9 11.7 20.4 2.3 11.7 1.3 0.3 3.2 0.8 7.8 1.9 3.8 10670.6 16.8 11.6 51.9 2.3 22.0 2.7 11.6 11.6 1.3 5.0 0.0 4.5 10.3 11.6 6.1 0.1 0.4 3.6 0.7 16.5 21.7 1.6 0.1 11.6 0.7 2.0 1.7 11.6 2.1 2.0 9.4 0.5 19.3 5.0 15.8 0.0 0.0 0.8 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 2.0 0.4 0.0 0.5 0.0 0.0 6.7 0.0 0.4 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.5 0.0 44.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.1 1.1 0.0 0.0 2.2 3.3 0.0 0.0 1077.7 0.0 0.7 0.4 1.1 0.8 0.1 2.0 0.0 61.2 0.0 0.0 0.0 0.0 35.5 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 13.9 11.7 20.4 16.8 11.6 11.6 11.6 11.6 11.6 11.6 15.8 0.6 3.2 3.0 0.3 0.0 3.4 1.4 1.7 1.8 3.9 0.9 1.7 12561.8 0.0 1.1 1.8 0.0 3.5 0.0 2.3 0.0 0.4 11.6 1.2 0.2 93.3 0.0 0.0 9.4 0.4 1.2 385.3 1.1 2.4 0.0 0.0 0.0 0.0 3.1 0.0 0.5 1.7 0.0 0.0 0.8 19.3 0.6 0.3 0.0 1.9 2.6 0.0 0.0 0.5 0.7 1.2 1.4 1.2 0.0 2.1 0.8 0.9 0.7 0.6 0.0 8.7 145.8 0.5 0.2 2.5 7.2 4.2 0.1 0.8 3.2 1.5 TNRC18 "CAGL79, KIAA1856, TNRC18A" ENSG00000182095 "Trinucleotide repeat containing 18" O15417 7 5306790-5425414 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 20.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020730, HPA024251" Uncertain Supported "Nucleoplasm,Nuclear membrane,Mitochondria,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Nuclear membrane, Mitochondria" Cytosol "HPA020730: AB_2670506, HPA024251: AB_2671498" "unprognostic (1.66e-1)" "unprognostic (3.17e-3)" "unprognostic (2.67e-3)" "unprognostic (4.44e-1)" "unprognostic (1.81e-1)" "unprognostic (6.67e-2)" "unprognostic (1.13e-2)" "unprognostic (1.79e-1)" "unprognostic (3.01e-1)" "unprognostic (2.11e-2)" "unprognostic (6.08e-2)" "unprognostic (1.36e-1)" "unprognostic (9.29e-3)" "unprognostic (2.14e-1)" "unprognostic (2.94e-1)" "unprognostic (1.02e-1)" "unprognostic (4.34e-2)" 30.4 18.3 10.8 29.0 8.9 51.8 30.1 16.2 14.2 40.8 2.2 56.3 25.3 57.6 16.4 26.0 43.5 22.4 22.1 10.3 0.5 22.9 19.8 32.0 16.1 6.2 1.7 46.0 29.5 35.0 22.2 30.6 1.6 36.1 22.6 12.2 28.8 34.3 24.0 33.2 29.0 36.4 1.3 25.2 33.8 22.6 5.1 17.2 32.6 11.1 14.6 40.8 31.9 3.2 72.8 63.4 51.5 43.4 42.9 50.6 133.8 50.4 47.3 27.4 29.0 26.3 62.4 49.3 48.3 74.7 60.8 79.7 30.2 60.5 23.0 21.6 19.2 31.4 56.6 43.1 37.1 104.3 111.2 51.2 70.0 54.8 63.2 39.5 31.3 43.6 45.4 27.2 35.3 120.0 24.6 127.2 4.5 47.5 48.0 27.0 25.7 37.3 22.3 91.3 22.3 53.4 38.8 102.5 37.0 23.1 106.9 106.1 78.7 78.3 109.6 47.0 36.7 38.6 44.1 46.2 44.1 72.6 94.1 14.2 3.8 3.6 1.7 1.5 1.2 2.2 1.2 1.0 1.4 2.3 0.9 1.7 20.8 3.2 2.1 5.4 1.9 0.2 10.8 8.9 16.2 14.2 10.3 0.5 6.2 1.7 1.6 1.3 5.1 3.2 25.6 9.6 29.0 59.7 7.4 9.3 3.7 9.8 13.6 51.7 15.8 25.9 7.5 14.3 12.4 14.7 2.1 14.5 20.4 33.6 1.9 5.0 14.4 22.2 29.7 17.3 31.3 9.7 40.9 6.6 3.8 17.8 19.4 36.2 14.0 48.3 29.6 25.4 11.2 50.5 45.6 30.4 8.2 41.8 12.4 18.8 18.3 22.8 5.4 71.2 25.9 31.0 11.3 32.6 20.3 9.0 10.6 19.9 12.1 6.5 7.4 5.4 11.1 4.0 19.7 18.4 21.2 0.4 2.1 12.5 8.8 10.0 12.3 18.6 25.1 3.8 TP53BP1 "53BP1, p202, TDRD30" ENSG00000067369 "Tumor protein p53 binding protein 1" Q12888 15 43403061-43510728 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004083, HPA008788, HPA022133, CAB079980" Supported Supported "Nucleoplasm,Nuclear bodies,Mitotic chromosome,Vesicles" Yes No "Cluster 46: Basophils - DNA binding" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" "Nuclear bodies" "Nucleoplasm, Mitotic chromosome, Vesicles" "CAB004083: AB_10694558, CAB079980: , HPA008788: AB_1078070, HPA022133: AB_1844382" "unprognostic (2.12e-1)" "unprognostic (7.96e-2)" "unprognostic (1.11e-1)" "unprognostic (1.85e-2)" "unprognostic (4.42e-3)" "unprognostic (2.32e-1)" "unprognostic (2.03e-2)" "unprognostic (3.96e-1)" "unprognostic (2.17e-1)" "unprognostic (2.81e-2)" "unprognostic (3.34e-2)" "unprognostic (4.07e-1)" "unprognostic (8.06e-2)" "unprognostic (9.11e-2)" "unprognostic (1.52e-1)" "unprognostic (6.99e-2)" "unprognostic (3.38e-2)" 6.9 11.5 17.4 10.1 16.6 11.5 10.7 19.9 14.5 17.7 21.5 9.7 6.4 16.0 15.9 6.1 14.7 10.7 8.8 15.4 26.3 9.1 4.1 8.3 8.6 13.5 16.7 16.8 7.4 22.3 24.1 12.2 15.7 12.1 10.2 22.0 10.1 12.8 7.2 9.2 6.4 16.3 9.6 8.7 7.6 21.6 23.0 15.3 17.9 11.0 12.6 11.2 8.7 12.1 13.5 22.3 63.8 40.1 25.8 31.9 15.8 22.8 33.8 31.0 39.1 19.4 15.8 14.5 19.2 39.0 66.9 32.4 46.3 27.5 36.8 38.9 15.8 27.1 40.1 11.7 16.8 30.2 37.4 24.9 19.0 41.8 31.2 51.7 37.4 24.2 26.9 12.3 36.5 9.6 23.7 14.1 41.1 24.2 13.9 25.1 23.9 9.3 22.9 31.8 57.3 26.8 33.8 14.3 8.5 48.6 29.9 16.9 27.5 33.7 22.3 27.0 20.5 9.8 22.4 33.0 27.6 14.6 17.5 1.4 0.5 1.0 1.6 0.7 1.3 1.9 1.6 1.6 1.2 1.8 1.8 1.6 0.6 0.9 0.5 1.3 1.4 0.7 17.4 16.6 19.9 14.5 15.4 26.3 13.5 16.7 15.7 9.6 23.0 12.1 11.5 22.4 22.3 53.2 17.8 6.4 10.2 10.0 13.6 32.4 17.4 13.2 14.9 5.7 20.8 29.5 47.9 13.4 11.1 7.4 9.8 14.5 38.8 47.0 44.8 16.8 41.9 8.4 66.2 7.1 11.2 23.9 14.8 26.8 26.6 47.0 15.0 3.3 10.8 47.1 81.9 15.7 12.2 3.8 6.9 17.8 23.6 9.3 1.8 17.8 4.0 11.9 7.2 62.8 50.4 7.5 5.8 17.7 17.1 11.0 2.6 8.8 60.7 51.7 13.1 35.2 20.5 33.1 36.2 14.7 5.3 18.5 17.0 29.9 13.4 8.9 TRMT10A "MGC27034, RG9MTD2, TRM10" ENSG00000145331 "TRNA methyltransferase 10A" Q8TBZ6 4 99546709-99564039 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Methyltransferase, Transferase" "Diabetes mellitus, Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 99.5;Spermatogonia: 55.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047601, HPA058241" Uncertain Supported "Nucleoplasm,Nucleoli,Actin filaments,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Nucleoli, Actin filaments" Cytosol "HPA047601: AB_2680099, HPA058241: AB_2683651" "unprognostic (5.24e-2)" "unprognostic (1.69e-1)" "unprognostic (1.34e-1)" "unprognostic (1.96e-3)" "unprognostic (2.10e-1)" "unprognostic (5.65e-2)" "unprognostic (1.04e-1)" "unprognostic (1.02e-1)" "unprognostic (1.59e-2)" "unprognostic (3.65e-2)" "unprognostic (1.57e-1)" "unprognostic (3.51e-1)" "unprognostic (7.49e-3)" "unprognostic (3.32e-2)" "unprognostic (2.78e-2)" "prognostic unfavorable (2.14e-4)" "unprognostic (1.68e-2)" 4.3 3.7 2.0 3.1 2.6 2.2 4.4 2.6 2.9 1.9 1.5 3.6 4.3 2.7 3.9 3.6 5.8 3.4 2.3 1.8 2.5 4.9 9.8 2.4 4.4 2.6 2.5 3.3 5.9 3.7 2.3 3.7 2.9 4.1 3.6 2.8 3.9 2.2 3.9 3.7 4.5 2.7 2.7 3.5 4.4 9.9 2.4 4.3 6.1 2.7 4.4 2.9 2.0 4.3 8.2 5.4 10.1 5.7 6.0 8.4 7.8 9.6 3.7 5.8 4.1 4.9 9.4 10.9 3.7 5.6 5.9 4.4 10.9 5.1 8.6 13.7 5.4 8.0 4.4 7.6 5.5 19.6 7.8 5.4 14.4 5.7 14.0 3.0 6.4 10.0 17.5 9.4 4.5 9.4 16.4 3.5 6.5 13.8 5.0 9.5 10.2 7.2 8.5 6.8 6.3 5.8 5.3 28.3 9.9 8.5 9.3 7.8 4.9 6.9 7.2 5.5 11.1 7.0 12.4 10.0 4.9 10.9 4.7 2.7 3.9 2.1 1.8 3.8 1.7 3.5 3.3 3.3 5.2 5.8 3.5 3.2 4.9 3.3 3.4 3.0 3.9 1.9 2.0 2.6 2.6 2.9 1.8 2.5 2.6 2.5 2.9 2.7 2.4 4.3 7.2 3.2 10.3 8.8 8.7 8.2 5.6 8.4 10.2 4.3 12.1 8.6 6.4 11.5 6.6 11.0 4.2 16.8 6.1 10.6 43.0 13.8 46.8 33.5 12.1 7.2 7.2 2.1 5.3 19.3 16.4 6.9 8.6 21.6 8.2 11.0 8.2 32.6 8.5 5.0 4.6 11.1 12.2 8.1 4.1 17.0 6.5 5.0 5.4 1.9 8.4 8.7 5.2 3.5 19.7 14.1 11.0 7.5 10.4 4.8 19.0 31.9 20.6 5.9 13.1 5.7 8.1 99.5 55.0 10.2 9.5 17.5 5.5 8.1 10.6 6.6 TRMT13 "CCDC76, FLJ10287, FLJ11219" ENSG00000122435 "TRNA methyltransferase 13 homolog" Q9NUP7 1 100133150-100150498 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 97.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA028494 Approved Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Plasma membrane" "Nuclear bodies, Cytosol" "HPA028494: AB_10601254" "unprognostic (1.12e-1)" "unprognostic (3.33e-1)" "unprognostic (5.76e-2)" "unprognostic (2.37e-1)" "unprognostic (9.17e-3)" "unprognostic (4.97e-2)" "prognostic unfavorable (5.81e-5)" "unprognostic (1.16e-3)" "unprognostic (3.28e-2)" "unprognostic (8.08e-2)" "unprognostic (3.22e-1)" "unprognostic (1.02e-3)" "prognostic unfavorable (6.89e-6)" "unprognostic (3.12e-2)" "unprognostic (7.71e-2)" "unprognostic (1.99e-2)" "unprognostic (1.70e-3)" 8.8 8.7 6.9 12.2 9.8 5.2 14.5 9.6 9.6 11.2 6.7 9.3 11.2 13.9 11.8 8.5 9.2 7.2 8.0 6.5 9.7 8.8 8.7 7.8 18.2 8.5 9.0 13.5 11.5 12.9 6.8 10.7 8.7 10.4 11.3 21.7 9.1 8.1 13.1 14.7 10.7 10.1 7.0 14.1 10.0 9.4 8.5 11.3 12.0 6.2 14.6 9.5 10.3 14.9 17.5 10.0 16.5 11.5 8.7 16.9 18.0 18.0 7.1 13.4 11.1 11.9 7.0 28.7 21.8 14.4 8.9 15.4 30.6 14.0 23.1 29.0 24.2 17.2 23.1 11.6 15.7 30.0 15.4 11.9 15.5 25.5 33.3 8.4 12.4 21.0 36.6 17.9 13.6 6.7 24.6 15.6 23.0 16.7 19.9 26.0 25.0 15.7 11.1 13.6 10.7 17.9 16.6 15.8 21.6 16.1 9.3 26.1 13.0 17.8 11.9 15.1 24.3 22.8 20.0 34.0 20.1 23.5 7.0 0.2 5.8 3.1 10.5 6.1 13.0 19.9 11.3 10.6 7.0 18.7 16.8 14.0 2.5 7.9 5.1 12.8 8.6 5.6 6.9 9.8 9.6 9.6 6.5 9.7 8.5 9.0 8.7 7.0 8.5 14.9 13.1 25.6 17.0 34.0 29.0 9.7 14.2 14.2 19.9 38.9 10.7 7.9 11.1 12.8 22.2 14.7 29.2 14.2 18.9 8.0 13.7 10.5 20.9 14.3 21.0 15.7 20.4 11.3 23.1 6.1 10.2 13.7 11.7 8.0 21.5 18.7 17.9 11.4 7.6 28.6 32.1 9.9 18.3 10.1 7.0 6.0 24.8 10.3 10.6 25.3 14.7 16.6 41.2 33.7 97.4 8.5 9.6 18.4 9.0 12.6 13.0 10.7 20.4 44.7 19.7 16.0 13.4 47.6 21.9 12.2 11.9 7.3 21.5 15.8 13.6 10.0 TSPAN31 SAS ENSG00000135452 "Tetraspanin 31" Q12999 12 57738013-57750219 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 4 "glioma: 54.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RH-30: 139.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030758, HPA057489" Approved Approved "Nucleoplasm,Golgi apparatus,Cytokinetic bridge,Cytosol" Yes No "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 5: Muller glia cells - Visual perception" "Golgi apparatus" "Nucleoplasm, Cytokinetic bridge, Cytosol" "HPA030758: , HPA057489: AB_2683447" "unprognostic (2.66e-2)" "unprognostic (1.50e-1)" "unprognostic (1.91e-1)" "unprognostic (1.82e-1)" "unprognostic (8.96e-3)" "prognostic unfavorable (1.09e-4)" "unprognostic (4.31e-3)" "unprognostic (1.19e-1)" "unprognostic (6.51e-3)" "unprognostic (5.31e-2)" "unprognostic (2.68e-1)" "unprognostic (2.79e-1)" "prognostic favorable (9.91e-5)" "unprognostic (1.68e-1)" "unprognostic (1.59e-1)" "unprognostic (6.32e-2)" "unprognostic (1.58e-1)" 24.5 29.7 9.0 11.2 10.8 5.5 23.1 10.8 15.6 26.2 11.8 20.5 16.4 26.2 13.2 20.4 25.8 20.9 26.7 9.5 10.3 26.7 20.9 22.8 11.8 11.2 10.2 25.6 25.2 32.7 24.4 12.5 11.0 22.1 10.7 29.7 25.6 13.5 21.0 18.6 18.5 8.4 11.1 20.8 23.0 8.0 9.9 9.8 30.2 21.2 8.7 21.0 20.1 13.0 9.5 23.4 21.1 5.4 44.3 24.0 13.5 15.8 11.7 4.6 5.1 16.7 46.4 7.6 32.7 29.0 9.4 17.5 5.7 26.7 10.7 23.1 15.4 10.7 18.7 6.6 45.2 10.6 17.9 29.6 30.2 13.7 30.3 22.1 14.6 4.6 7.5 19.9 19.6 19.4 9.2 5.9 4.3 18.3 7.0 10.5 139.8 20.0 15.7 19.0 6.6 16.7 15.6 21.3 10.5 4.5 41.1 15.8 27.6 11.3 9.5 5.6 7.4 28.9 8.1 4.1 32.7 6.3 19.2 25.4 26.3 16.4 35.8 28.6 34.8 31.1 28.5 30.7 27.6 31.0 28.3 26.2 5.8 35.4 42.0 58.3 22.1 33.0 9.0 10.8 10.8 15.6 9.5 10.3 11.2 10.2 11.0 11.1 9.9 13.0 37.1 48.1 32.4 8.1 23.8 11.2 46.4 37.4 22.2 43.2 32.0 27.4 5.1 20.0 31.4 31.3 41.7 20.9 29.8 19.9 9.8 37.6 1.2 18.5 32.5 26.7 26.5 8.2 9.1 39.0 15.2 31.7 11.7 20.4 45.0 28.9 22.1 21.6 22.4 21.9 9.1 21.6 32.6 18.0 16.4 1.8 25.7 24.2 32.0 8.4 21.6 62.7 35.0 11.1 13.3 37.6 20.3 17.3 18.4 30.5 30.6 18.1 27.9 60.4 19.7 22.3 31.9 9.2 7.7 16.1 12.6 24.5 20.4 35.3 19.4 31.8 TSR2 "DT1P1A10, RP1-112K5.2, WGG1" ENSG00000158526 "TSR2 ribosome maturation factor" Q969E8 X 54440404-54448032 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "rRNA processing" "Diamond-Blackfan anemia, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030514 Approved Approved "Nucleoplasm,Nucleoli,Cell Junctions,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Nucleoli" "Cell Junctions, Cytosol" "HPA030514: AB_10603457" "unprognostic (1.05e-1)" "unprognostic (1.80e-2)" "unprognostic (1.77e-2)" "unprognostic (1.58e-2)" "unprognostic (2.64e-2)" "unprognostic (5.91e-2)" "unprognostic (7.15e-3)" "unprognostic (8.29e-2)" "unprognostic (4.39e-1)" "unprognostic (1.31e-1)" "unprognostic (2.94e-2)" "unprognostic (6.19e-2)" "prognostic favorable (1.21e-6)" "unprognostic (2.27e-1)" "unprognostic (1.13e-1)" "unprognostic (7.93e-3)" "unprognostic (1.80e-3)" 35.2 45.1 50.9 11.2 49.9 11.9 35.6 43.4 59.4 36.8 39.3 42.2 10.2 34.9 23.0 34.6 32.2 7.7 45.5 46.2 52.9 43.8 36.7 30.4 12.6 48.9 48.0 34.6 30.2 25.0 47.1 14.6 47.3 33.3 13.3 27.4 32.6 16.9 51.7 40.7 31.3 13.2 50.3 32.4 38.8 16.5 50.6 14.9 41.1 18.6 15.8 36.3 35.0 47.8 24.1 26.6 23.9 20.6 19.9 13.0 18.7 22.4 17.5 19.6 17.3 26.2 24.1 23.5 15.8 18.2 35.7 24.9 47.9 28.3 24.8 29.8 26.8 19.3 20.8 19.6 12.5 32.7 19.4 12.9 18.0 26.4 27.1 19.7 13.8 22.9 20.5 16.9 19.3 37.9 27.4 29.9 34.6 23.6 33.0 26.5 38.2 19.6 20.6 18.3 25.9 20.5 42.1 19.9 28.0 38.0 45.4 14.7 21.0 16.2 27.1 38.0 19.9 19.8 32.3 29.7 24.4 27.5 23.2 29.7 16.6 32.0 36.3 23.1 30.0 44.8 34.0 33.6 15.1 46.3 42.6 32.3 10.4 29.7 26.0 16.7 40.8 24.9 50.9 49.9 43.4 59.4 46.2 52.9 48.9 48.0 47.3 50.3 50.6 47.8 39.1 25.6 30.2 1.6 39.8 32.8 43.0 42.7 26.7 61.6 27.4 28.6 49.0 28.6 38.6 35.0 27.1 98.5 36.0 26.3 125.2 43.9 1.2 17.7 23.7 35.6 18.1 18.1 5.7 32.9 71.5 33.8 16.8 22.9 45.0 20.3 31.8 25.2 46.6 57.2 5.6 35.5 61.1 18.2 31.4 2.8 34.8 24.6 40.9 6.5 48.6 85.6 44.3 2.5 6.5 38.1 29.5 45.1 22.3 36.7 32.6 64.6 33.8 67.0 46.0 29.8 38.0 20.5 43.3 25.4 31.7 75.9 37.8 36.2 30.9 33.9 UBA3 "hUba3, NAE2, UBE1C" ENSG00000144744 "Ubiquitin like modifier activating enzyme 3" Q8TBC4 3 69054730-69080408 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Ubl conjugation pathway" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "brain: 383.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034873, HPA034874, HPA065335" Supported Approved "Nucleoplasm,Plasma membrane,Centrosome,Cytosol" NA NA 35000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 44: HDLM-2 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane, Cytosol" "Nucleoplasm, Centrosome" "HPA034873: AB_10670578, HPA034874: AB_2674368, HPA065335: AB_2685473" "unprognostic (2.31e-1)" "unprognostic (1.75e-1)" "unprognostic (5.56e-3)" "unprognostic (9.26e-2)" "unprognostic (9.35e-3)" "unprognostic (5.53e-2)" "prognostic unfavorable (8.57e-4)" "unprognostic (1.08e-1)" "unprognostic (6.18e-2)" "unprognostic (1.60e-3)" "unprognostic (9.40e-2)" "unprognostic (2.71e-2)" "unprognostic (1.39e-3)" "unprognostic (2.61e-3)" "unprognostic (9.24e-2)" "unprognostic (7.80e-3)" "unprognostic (2.52e-1)" 34.3 32.3 83.7 39.4 225.9 39.1 43.4 138.0 136.2 32.1 32.1 34.5 28.8 35.8 41.0 33.9 27.5 29.7 66.6 109.7 198.7 33.9 31.2 32.2 49.6 240.4 162.7 30.0 19.3 45.6 22.9 41.7 245.4 36.6 35.8 62.0 44.9 32.2 41.5 45.0 30.3 39.8 131.0 38.9 26.4 23.7 197.1 44.8 27.1 34.7 49.8 39.4 26.6 383.0 76.6 31.4 75.8 47.1 69.0 90.9 56.1 65.9 74.4 70.4 70.2 39.2 52.2 55.2 18.6 72.5 71.3 42.1 59.1 76.5 80.2 105.0 38.5 77.0 57.7 39.6 53.8 77.1 62.4 72.0 49.8 67.9 54.9 86.7 92.3 45.2 31.9 45.6 94.0 26.8 49.5 49.7 67.5 95.4 26.9 39.6 55.9 53.0 113.2 94.6 32.8 46.2 70.3 51.0 58.4 80.9 34.3 73.3 71.4 53.0 46.9 70.6 93.3 53.2 91.8 67.3 54.5 84.3 69.7 87.9 45.7 71.0 24.3 54.0 28.1 33.6 32.2 30.3 40.1 29.7 29.6 30.5 40.9 39.8 57.1 20.1 40.8 53.0 83.7 225.9 138.0 136.2 109.7 198.7 240.4 162.7 245.4 131.0 197.1 383.0 21.9 35.3 31.4 35.9 35.5 33.8 29.2 66.2 31.9 22.9 21.6 17.9 68.5 14.3 44.5 35.0 39.6 74.5 19.8 15.8 19.6 37.1 15.2 25.1 21.2 26.9 18.6 30.7 44.6 23.6 57.2 28.3 22.4 25.6 42.4 26.0 22.9 17.2 34.1 33.7 62.8 16.3 97.6 37.1 49.6 10.3 40.4 39.6 30.2 44.0 60.6 29.1 24.7 53.3 76.7 31.5 11.7 38.0 28.3 23.7 16.7 36.9 47.3 48.9 26.3 22.2 31.0 34.2 32.1 34.9 42.8 56.8 34.0 24.3 17.5 32.5 UBA52 "CEP52, HUBCEP52, L40, MGC126879, MGC126881, MGC57125, RPL40" ENSG00000221983 "Ubiquitin A-52 residue ribosomal protein fusion product 1" P62987 19 18571730-18577550 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 11928.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041344, HPA049132, HPA056624" Supported Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" "Nucleoplasm, Plasma membrane" "HPA041344: AB_2677422, HPA049132: AB_2680646, HPA056624: AB_2683196" "unprognostic (1.98e-2)" "unprognostic (9.35e-2)" "unprognostic (1.46e-1)" "unprognostic (4.72e-2)" "unprognostic (5.36e-3)" "unprognostic (9.35e-2)" "unprognostic (1.74e-3)" "unprognostic (4.00e-2)" "unprognostic (7.44e-2)" "unprognostic (1.72e-1)" "unprognostic (1.27e-1)" "unprognostic (2.87e-1)" "unprognostic (2.52e-3)" "unprognostic (1.87e-1)" "unprognostic (5.61e-2)" "unprognostic (2.43e-1)" "unprognostic (2.23e-1)" 1161.5 955.0 823.8 793.2 845.7 2181.5 1115.4 815.0 1021.1 1262.7 808.6 984.4 531.1 938.2 966.2 1196.8 984.5 610.9 989.3 803.8 848.5 931.1 927.4 888.7 1469.5 861.9 825.6 1622.0 1664.8 844.0 758.0 720.8 858.2 917.0 789.6 235.6 1061.1 615.4 1629.9 1444.0 916.6 712.9 883.0 1239.2 989.5 755.3 853.4 1487.1 748.6 1196.7 1674.0 995.3 1107.5 875.5 1680.6 1304.1 961.2 1612.8 2437.7 2298.9 2376.3 1260.7 1738.5 2044.2 1618.9 2381.2 1521.6 2403.4 1268.0 2092.8 803.0 1103.3 1881.9 2242.7 1918.7 650.0 2938.0 1320.1 1942.1 2733.4 1770.8 2898.3 1616.2 2684.2 3008.4 1406.4 2024.7 1778.7 2083.2 1508.8 2131.5 3231.7 1769.8 2786.9 2336.4 2584.2 2162.6 3166.1 2800.9 1899.3 958.6 2769.6 2001.7 2497.0 1246.1 1505.9 914.3 2187.0 2300.9 1424.6 970.6 3681.4 1562.7 1017.6 850.0 2172.8 2271.9 1973.0 2863.7 2412.2 1386.0 3245.8 1412.8 962.6 2155.2 1163.1 1761.2 1764.2 2401.7 3126.7 2616.4 2119.8 2320.3 3025.4 2946.4 2445.0 1168.8 1864.5 1629.2 2469.2 2250.9 4829.5 823.8 845.7 815.0 1021.1 803.8 848.5 861.9 825.6 858.2 883.0 853.4 875.5 831.5 464.8 673.1 15.0 2198.0 1898.4 2027.9 1544.8 1365.8 117.9 1444.5 1279.9 332.3 1109.5 886.1 654.7 68.8 2020.5 1806.7 1264.6 1571.0 1437.7 3146.5 772.1 1337.9 1108.6 1106.6 2241.7 10.8 2271.5 2803.3 1060.1 672.2 1194.9 805.8 1061.9 1385.3 1919.9 2574.7 104.3 12.4 1812.7 710.1 3200.4 2894.6 11928.8 1875.2 2003.3 1250.4 8.4 3379.8 599.1 2276.1 11.1 23.1 1799.4 1853.6 1034.7 1202.4 2110.3 1645.1 2688.2 510.4 219.1 696.8 1483.1 2041.1 629.9 674.5 1939.2 2239.4 2282.9 1892.0 1285.6 1783.6 2426.6 UBE2A "HHR6A, HR6A, RAD6A, UBC2" ENSG00000077721 "Ubiquitin conjugating enzyme E2 A" P49459 X 119574536-119591083 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Chromatin regulator, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 508.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003875, HPA051765, HPA065898" Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA003875: AB_2667061, HPA051765: AB_2681597, HPA065898: AB_2685577" "unprognostic (2.27e-3)" "prognostic favorable (2.16e-4)" "unprognostic (1.12e-1)" "unprognostic (9.09e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (9.07e-4)" "unprognostic (1.66e-3)" "unprognostic (1.96e-2)" "unprognostic (6.54e-2)" "unprognostic (2.96e-2)" "unprognostic (3.49e-2)" "unprognostic (1.33e-1)" "prognostic unfavorable (2.20e-6)" "unprognostic (9.54e-2)" "unprognostic (3.06e-2)" "unprognostic (1.21e-1)" "unprognostic (7.92e-2)" 40.0 27.4 30.1 39.1 30.6 29.8 29.4 34.1 38.8 34.1 27.1 52.3 37.5 32.0 38.2 53.4 27.3 32.6 63.2 29.6 32.2 41.0 30.1 32.9 46.9 34.4 32.5 20.1 29.2 39.2 18.9 56.8 34.4 31.0 45.0 27.1 30.9 33.0 71.9 30.7 39.1 43.0 32.1 26.8 30.5 17.6 32.1 46.1 30.5 55.0 50.4 46.9 32.8 35.1 129.5 104.1 60.8 54.1 103.0 125.6 63.9 122.6 106.3 141.8 130.3 50.8 84.0 96.4 126.4 133.9 240.6 86.4 86.3 65.7 128.6 142.3 60.6 42.7 71.9 47.1 96.6 105.9 72.1 86.9 90.1 134.0 58.3 98.1 99.4 86.5 57.0 83.6 160.1 134.5 166.6 99.9 106.3 125.7 126.9 84.2 64.0 91.6 113.1 76.6 48.9 51.3 171.2 75.0 93.7 73.2 65.8 92.6 101.5 92.4 42.0 184.3 142.5 83.6 147.1 92.4 99.1 136.3 74.6 46.8 58.5 92.5 43.0 92.1 34.8 52.6 37.9 38.5 74.6 48.7 23.7 33.9 78.0 35.0 101.1 58.5 56.8 51.1 30.1 30.6 34.1 38.8 29.6 32.2 34.4 32.5 34.4 32.1 32.1 35.1 67.5 102.5 40.9 12.7 79.1 124.8 91.6 129.4 51.8 17.2 60.7 43.9 66.7 44.3 80.7 40.5 31.3 179.8 93.0 168.6 101.8 95.4 51.7 75.6 55.3 62.9 45.5 70.4 9.9 102.1 176.2 67.7 37.8 63.0 57.0 35.7 46.4 35.5 131.3 8.4 9.4 49.7 103.7 59.1 183.9 15.3 37.0 97.3 83.6 15.9 129.0 49.8 41.2 14.6 18.0 137.6 132.5 40.6 92.2 98.2 85.6 125.2 107.7 35.0 46.0 56.3 101.1 44.1 32.1 74.6 127.9 508.5 94.8 36.6 54.5 120.3 UBE2B "HHR6B, RAD6B, UBC2" ENSG00000119048 "Ubiquitin conjugating enzyme E2 B" P63146 5 134371469-134392108 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 265.8" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 723.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 444.6" "Lineage enriched" "Detected in all" 6 "granulocytes: 444.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003875, HPA051765, HPA065898" Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA003875: AB_2667061, HPA051765: AB_2681597, HPA065898: AB_2685577" "unprognostic (1.98e-1)" "unprognostic (1.35e-1)" "unprognostic (7.39e-2)" "unprognostic (6.66e-2)" "unprognostic (1.44e-1)" "unprognostic (1.48e-2)" "unprognostic (2.56e-1)" "unprognostic (1.27e-1)" "unprognostic (1.91e-1)" "unprognostic (2.44e-1)" "unprognostic (2.49e-1)" "unprognostic (8.39e-2)" "unprognostic (1.64e-3)" "unprognostic (6.30e-3)" "unprognostic (3.42e-2)" "unprognostic (2.04e-1)" "unprognostic (5.52e-2)" 52.5 74.2 31.5 50.0 33.1 84.4 44.2 36.3 53.2 38.3 30.2 48.0 40.7 53.6 34.8 70.5 37.3 51.0 118.4 34.3 34.8 50.6 56.6 44.9 47.1 29.5 31.0 44.4 53.7 25.8 39.9 48.4 31.0 32.9 42.0 29.2 39.7 23.2 265.8 43.1 46.4 43.3 30.3 43.7 39.6 49.2 32.9 29.3 41.2 99.8 48.1 42.8 43.2 36.7 109.4 27.9 58.2 55.0 50.0 54.1 92.7 80.2 43.5 51.4 60.9 85.6 70.9 58.7 94.1 52.3 138.7 42.7 45.8 60.4 56.0 94.5 47.6 32.1 75.9 92.8 58.2 38.8 63.7 46.5 80.2 47.4 39.3 68.1 44.1 48.8 61.1 103.5 46.8 63.4 62.5 102.1 24.9 32.6 26.7 61.6 63.8 83.8 46.6 82.9 77.6 60.1 62.9 29.3 147.9 62.5 63.0 106.0 87.6 57.8 40.8 78.9 89.4 86.1 129.4 87.0 65.2 72.8 59.4 236.7 58.3 174.0 46.9 68.3 42.9 49.7 58.8 48.1 42.6 47.9 69.9 60.6 444.6 53.0 78.9 48.0 77.5 64.1 31.5 33.1 36.3 53.2 34.3 34.8 29.5 31.0 31.0 30.3 32.9 36.7 187.5 73.7 61.6 40.1 176.5 364.7 321.2 215.1 175.8 77.8 169.9 156.5 315.8 147.3 113.7 75.4 81.3 144.5 182.0 183.1 172.1 173.8 233.2 139.8 102.2 149.7 131.8 261.2 103.0 169.5 123.0 183.3 113.2 167.8 116.8 81.7 115.3 97.4 119.4 87.5 84.2 141.0 181.0 131.5 323.9 315.4 155.0 184.2 227.7 49.6 190.6 150.0 113.3 44.7 68.4 210.6 195.2 113.2 162.5 343.9 153.4 170.7 111.7 91.3 151.2 154.9 262.9 223.5 201.7 145.5 369.7 723.5 192.0 140.4 105.7 488.1 UBE2M "hUbc12, UBC12" ENSG00000130725 "Ubiquitin conjugating enzyme E2 M" P61081 19 58555712-58558954 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEK 293: 1197.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004993, HPA054551, HPA057800" Approved Enhanced "Nucleoplasm,Nucleoli,Nuclear bodies,Cytosol" Yes No 49000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Nucleoli, Nuclear bodies, Cytosol" "CAB004993: AB_436983, HPA054551: AB_2682520, HPA057800: AB_2683531" "unprognostic (1.42e-1)" "unprognostic (1.99e-1)" "unprognostic (1.63e-2)" "unprognostic (1.39e-1)" "unprognostic (8.35e-2)" "unprognostic (1.77e-1)" "unprognostic (1.17e-3)" "unprognostic (3.90e-3)" "unprognostic (4.86e-2)" "unprognostic (1.09e-2)" "unprognostic (3.05e-3)" "unprognostic (1.96e-1)" "unprognostic (1.81e-1)" "unprognostic (8.63e-3)" "unprognostic (1.76e-1)" "unprognostic (5.85e-2)" "unprognostic (8.42e-3)" 46.3 66.1 133.2 39.2 138.8 82.2 42.8 116.7 199.7 48.9 104.0 72.5 41.7 48.1 36.3 61.8 51.3 30.9 111.0 141.2 129.3 63.2 45.6 46.3 43.4 123.5 124.4 46.0 47.5 84.5 69.7 45.0 127.7 48.3 32.5 49.7 48.5 46.1 174.0 56.6 41.6 39.5 111.9 49.3 55.8 81.0 124.4 51.7 44.3 104.5 43.7 58.3 45.8 139.1 161.8 272.1 119.3 124.8 61.7 71.9 112.2 166.0 117.4 97.8 82.8 162.7 109.7 161.9 135.5 93.4 198.1 105.9 130.1 138.6 69.2 207.3 1197.4 235.5 163.7 113.7 154.4 197.3 192.9 82.1 107.1 145.9 167.3 102.6 117.8 146.3 119.6 179.4 127.3 158.2 177.2 223.7 87.1 155.1 306.5 171.7 106.7 204.5 111.6 166.8 239.5 205.5 133.1 149.7 163.3 41.6 94.4 188.4 105.2 333.4 80.5 110.6 281.3 262.3 411.9 169.6 206.0 177.6 220.5 6.7 3.6 4.2 3.0 2.6 2.2 2.8 3.2 3.2 2.8 3.8 3.3 2.2 10.1 1.7 2.7 6.7 2.9 1.9 133.2 138.8 116.7 199.7 141.2 129.3 123.5 124.4 127.7 111.9 124.4 139.1 75.1 6.4 13.0 14.7 32.7 40.4 36.3 15.9 6.2 100.0 74.5 81.3 38.5 20.0 11.6 18.4 20.9 21.0 72.9 63.9 7.9 17.3 25.7 89.6 68.0 40.1 41.2 39.8 22.9 30.6 22.4 38.9 21.9 63.3 19.7 103.3 28.5 38.0 35.4 109.4 20.8 43.8 20.3 27.0 33.5 34.0 17.4 42.5 35.6 15.9 21.1 142.3 14.4 8.5 17.9 41.8 21.4 13.9 35.4 59.1 37.9 33.9 18.6 81.1 26.3 41.5 55.4 27.1 7.9 17.0 56.8 52.5 41.0 156.1 41.6 56.2 UNC13B "hmunc13, Munc13-2, UNC13, Unc13h2" ENSG00000198722 "Unc-13 homolog B" O14795 9 35161992-35405338 "Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 57.7;Alveolar cells type 2: 80.7;Cone photoreceptor cells: 95.9;Excitatory neurons: 60.4;Microglial cells: 73.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024493, HPA062300" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles,Intermediate filaments" Yes No "Cluster 77: Retina - Visual perception" "Cluster 21: OE19 - Mitochondria" "Cluster 9: Photoreceptor cells - Phototransduction" Vesicles "Nucleoplasm, Golgi apparatus, Intermediate filaments" "HPA024493: AB_1858618, HPA062300: AB_2684742" "unprognostic (9.73e-3)" "unprognostic (2.33e-1)" "prognostic favorable (4.96e-4)" "unprognostic (6.56e-2)" "unprognostic (9.93e-2)" "prognostic favorable (8.51e-5)" "unprognostic (7.64e-2)" "prognostic favorable (6.59e-5)" "unprognostic (3.80e-1)" "unprognostic (1.64e-1)" "prognostic favorable (3.71e-4)" "unprognostic (1.74e-1)" "prognostic favorable (4.34e-11)" "unprognostic (2.40e-1)" "unprognostic (1.89e-1)" "unprognostic (1.48e-1)" "unprognostic (2.80e-2)" 12.6 12.8 10.5 5.6 13.3 1.0 10.3 6.6 14.5 12.5 15.7 22.2 11.6 10.1 7.7 17.5 10.4 11.5 13.6 11.4 7.2 21.8 12.8 38.9 1.8 8.3 9.5 7.3 21.3 15.0 11.5 6.0 7.8 22.6 25.0 41.2 17.8 23.3 24.2 12.3 13.4 11.9 7.3 4.7 17.9 15.6 10.6 3.0 12.2 10.4 5.0 10.2 12.7 9.0 9.8 12.8 13.9 22.6 26.3 14.6 11.8 15.7 7.1 11.4 15.3 10.7 4.5 0.0 7.0 20.6 20.1 4.7 35.4 18.2 14.5 0.0 11.3 5.9 36.6 13.9 12.7 2.2 6.4 11.6 14.0 18.0 18.5 18.2 37.3 15.8 13.5 8.1 13.5 7.5 2.1 0.2 12.6 30.2 13.3 0.1 8.6 3.4 15.5 12.6 14.9 15.7 11.0 6.8 11.4 23.0 11.6 7.5 34.5 7.8 7.2 12.3 12.2 12.7 16.2 0.0 8.5 18.4 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 13.3 6.6 14.5 11.4 7.2 8.3 9.5 7.8 7.3 10.6 9.0 6.7 57.7 80.7 28.7 0.8 3.1 1.1 2.1 3.4 42.3 7.3 4.4 11.4 18.6 16.7 9.2 95.9 3.7 0.1 24.4 3.9 6.0 6.9 8.2 5.1 8.5 24.6 1.7 60.4 12.2 2.1 4.8 16.3 13.9 2.5 8.7 5.7 12.5 4.9 6.7 17.7 31.9 0.0 2.4 3.0 12.3 2.1 3.7 7.2 73.1 0.1 5.7 0.0 42.3 36.7 7.8 11.9 3.0 4.2 11.7 10.5 7.8 10.0 40.8 6.6 8.4 6.5 8.7 7.5 14.3 7.4 2.9 1.0 5.7 19.5 5.7 UTP18 "CGI-48, WDR50" ENSG00000011260 "UTP18 small subunit processome component" Q9Y5J1 17 51260546-51297936 "Predicted intracellular proteins" "rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 190.6;Late spermatids: 182.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052378 Approved Supported "Nucleoplasm,Nuclear membrane,Nucleoli,Nucleoli rim" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoli, Nucleoli rim" "Nucleoplasm, Nuclear membrane" "HPA052378: AB_2681805" "unprognostic (1.36e-2)" "unprognostic (1.00e-1)" "prognostic favorable (3.33e-4)" "unprognostic (2.62e-2)" "unprognostic (2.55e-2)" "unprognostic (5.99e-2)" "prognostic unfavorable (1.99e-4)" "unprognostic (2.47e-2)" "unprognostic (8.37e-3)" "unprognostic (1.10e-2)" "unprognostic (8.82e-2)" "unprognostic (2.75e-2)" "unprognostic (3.11e-3)" "unprognostic (9.51e-2)" "unprognostic (1.59e-1)" "unprognostic (8.72e-3)" "unprognostic (1.93e-2)" 17.9 20.1 12.6 24.9 13.7 40.0 25.8 19.1 15.7 18.8 14.2 17.5 17.8 15.7 15.8 21.0 17.5 12.8 10.2 13.2 13.8 21.8 22.3 17.3 33.1 13.0 12.3 23.8 21.3 23.3 20.4 26.3 13.6 16.2 18.7 17.5 17.4 14.2 24.4 32.3 16.5 12.9 13.0 24.5 18.1 58.7 13.2 27.7 24.4 16.2 34.4 24.8 18.0 15.6 90.5 87.7 54.6 50.3 35.1 52.2 142.2 48.9 40.2 83.5 79.7 55.4 49.3 113.5 67.8 36.6 89.0 48.1 89.7 52.0 123.3 74.8 117.0 119.4 52.6 97.3 48.0 127.9 56.4 33.9 39.5 71.1 57.0 42.1 50.7 55.6 98.7 50.6 63.5 56.1 115.6 86.9 78.5 127.5 91.8 103.2 124.2 89.4 61.3 59.1 60.7 76.9 56.7 66.6 114.7 67.4 82.3 64.4 44.7 85.3 71.8 71.1 102.9 97.4 192.5 131.5 53.0 87.6 62.4 19.0 48.2 27.9 40.2 46.9 49.9 54.1 50.7 49.2 55.9 52.4 53.6 51.1 8.2 40.0 49.0 35.0 56.8 56.2 12.6 13.7 19.1 15.7 13.2 13.8 13.0 12.3 13.6 13.0 13.2 15.6 20.6 16.0 23.4 11.8 37.4 60.2 62.9 40.6 33.0 15.6 19.6 17.9 4.4 20.0 25.2 14.7 14.6 66.7 27.4 11.4 39.2 38.4 190.6 26.3 27.3 25.1 16.1 20.8 18.5 46.9 71.2 24.5 14.3 24.1 31.7 19.6 8.9 17.1 62.8 10.1 18.0 20.7 34.6 37.7 26.1 182.0 26.8 33.3 23.2 15.0 42.2 21.3 25.7 17.6 24.6 34.2 16.3 22.2 24.2 50.2 13.8 37.5 38.8 11.8 13.1 24.8 35.7 140.2 104.5 27.7 52.7 79.6 30.4 30.8 25.3 48.1 XPO1 "CRM-1, CRM1, emb" ENSG00000082898 "Exportin 1" O14980 2 61476032-61538741 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, mRNA transport, Protein transport, Transport" RNA-binding "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010184, HPA042933" Supported Enhanced "Nucleoplasm,Nuclear membrane,Vesicles,Cytosol" NA NA 410000 "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoplasm, Nuclear membrane" "Vesicles, Cytosol" "CAB010184: AB_2215817, HPA042933: AB_2678229" "unprognostic (7.34e-2)" "unprognostic (7.04e-2)" "unprognostic (6.37e-2)" "unprognostic (1.67e-2)" "unprognostic (5.61e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.84e-5)" "unprognostic (1.84e-1)" "unprognostic (1.99e-3)" "unprognostic (4.43e-1)" "unprognostic (3.53e-3)" "unprognostic (4.90e-2)" "prognostic unfavorable (3.74e-4)" "unprognostic (5.69e-2)" "unprognostic (2.08e-1)" "unprognostic (2.43e-1)" "unprognostic (5.55e-2)" 33.2 29.8 30.1 48.7 31.4 25.8 39.2 35.7 44.3 37.9 31.6 34.9 24.7 52.5 37.0 35.1 45.9 32.0 36.0 27.9 33.7 30.8 41.7 31.9 65.3 28.9 30.5 58.9 26.2 38.5 22.0 52.1 30.4 34.2 42.0 52.0 19.9 34.9 37.5 34.2 33.2 48.6 30.9 43.4 31.9 54.5 32.8 73.6 38.8 47.2 60.9 38.6 22.4 38.9 169.1 152.9 194.1 135.8 91.4 107.9 145.5 166.6 109.2 192.9 151.8 217.3 114.7 256.0 117.4 127.1 186.3 125.0 307.9 126.5 268.6 151.6 110.7 242.8 136.2 148.4 55.4 234.6 145.4 62.9 103.8 149.4 145.9 126.0 149.5 108.7 285.5 127.7 164.9 97.8 212.6 100.4 213.1 189.9 111.5 175.6 208.0 148.1 103.0 124.9 152.8 77.5 174.2 142.8 87.1 185.6 108.6 110.8 98.9 153.7 178.7 137.2 175.0 102.8 203.2 347.0 96.8 214.0 151.0 3.3 1.4 2.2 1.8 2.2 1.9 1.1 1.0 1.8 2.1 0.7 1.0 1.0 0.6 2.7 1.2 1.6 1.2 1.2 30.1 31.4 35.7 44.3 27.9 33.7 28.9 30.5 30.4 30.9 32.8 38.9 42.0 41.7 43.2 114.3 55.3 52.1 32.1 45.5 78.6 67.5 40.2 38.6 64.5 38.6 38.7 31.3 95.9 54.1 56.6 27.3 13.7 29.7 4.2 58.6 79.7 47.7 45.1 73.2 87.9 26.1 49.3 49.9 42.3 68.6 41.8 100.4 41.4 55.8 57.2 72.3 101.3 34.2 40.7 55.3 58.4 11.9 33.5 63.9 37.4 68.4 64.2 33.4 61.8 83.4 102.5 32.3 20.9 30.9 57.2 55.6 21.0 22.2 56.9 101.7 19.7 50.5 55.7 65.9 91.6 83.3 56.8 30.1 54.5 54.4 46.2 47.7 XPO6 "FLJ22519, KIAA0370, RANBP20" ENSG00000169180 "Exportin 6" Q96QU8 16 28097976-28211965 "Metabolic proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 90.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "neutrophil: 202.1" "Lineage enriched" "Detected in all" 9 "granulocytes: 202.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038246 Uncertain Approved "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" No No "Cluster 50: Neutrophils - Cellular senescence" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Nucleoli" "Plasma membrane, Cytosol" "HPA038246: AB_10674550" "unprognostic (1.17e-1)" "unprognostic (5.43e-2)" "unprognostic (1.07e-1)" "unprognostic (3.76e-1)" "unprognostic (1.38e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (3.68e-4)" "unprognostic (2.22e-1)" "unprognostic (1.41e-1)" "unprognostic (1.31e-2)" "unprognostic (4.48e-1)" "unprognostic (1.40e-1)" "unprognostic (1.01e-3)" "unprognostic (2.10e-1)" "unprognostic (5.36e-2)" "unprognostic (8.50e-2)" "prognostic unfavorable (8.80e-4)" 48.0 48.3 70.0 55.9 73.7 92.0 39.9 61.7 87.0 43.7 63.9 47.0 21.8 42.3 18.8 57.0 44.8 24.5 36.2 72.2 72.0 47.2 62.1 70.9 62.9 76.1 69.2 36.6 43.2 26.9 56.6 25.7 73.6 48.6 27.4 35.2 44.9 20.1 29.9 52.9 63.0 26.8 67.8 160.6 42.8 100.3 72.9 51.1 50.5 13.7 44.9 44.9 46.0 77.8 82.9 63.3 54.8 58.8 37.2 58.8 57.9 97.0 98.0 124.8 124.8 89.1 61.7 59.8 78.6 99.8 63.3 53.8 131.6 83.9 151.5 115.3 72.1 67.6 90.0 101.6 87.9 95.4 70.8 46.3 61.2 111.1 108.9 53.5 73.1 63.4 118.0 31.0 86.0 101.1 116.2 116.1 88.1 43.6 55.4 101.0 64.3 101.2 46.8 45.2 103.3 55.0 52.9 88.3 47.8 60.8 62.7 63.3 75.4 104.1 64.4 87.2 84.8 63.0 83.8 89.8 78.7 98.4 89.1 21.1 9.9 32.9 14.2 11.4 15.4 20.7 16.5 15.8 7.3 15.7 18.1 22.6 202.1 10.7 17.6 9.5 14.7 8.4 70.0 73.7 61.7 87.0 72.2 72.0 76.1 69.2 73.6 67.8 72.9 77.8 9.6 9.6 14.2 27.4 20.2 18.6 11.4 12.6 5.2 20.8 15.0 14.6 8.0 5.7 12.6 23.9 31.3 11.5 30.2 28.5 7.9 14.1 39.2 12.7 21.5 11.6 23.5 10.3 51.2 19.2 17.3 13.3 12.2 32.8 2.5 34.6 9.3 16.7 23.4 21.9 55.4 20.6 10.2 27.9 15.8 44.8 10.8 22.6 7.2 43.1 28.6 8.3 23.7 59.3 90.3 23.4 13.5 8.6 16.5 22.4 13.3 7.1 10.3 28.1 6.6 13.5 12.2 31.6 26.5 18.0 21.3 8.3 27.0 9.5 21.2 15.4 YIPF5 "FinGER5, SMAP-5" ENSG00000145817 "Yip1 domain family member 5" Q969M3 5 144158162-144170714 "Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "TIME: 236.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042338, HPA073622" Supported Supported "Nucleoplasm,Endoplasmic reticulum,Golgi apparatus,Vesicles" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum, Golgi apparatus, Vesicles" Nucleoplasm "HPA042338: AB_2677953, HPA073622: AB_2686618" "prognostic unfavorable (7.83e-5)" "unprognostic (1.13e-3)" "unprognostic (1.95e-2)" "unprognostic (8.35e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.12e-5)" "prognostic unfavorable (3.26e-5)" "unprognostic (2.89e-2)" "unprognostic (1.99e-1)" "unprognostic (3.64e-2)" "unprognostic (1.20e-3)" "unprognostic (4.79e-2)" "unprognostic (8.79e-2)" "unprognostic (1.69e-1)" "unprognostic (1.24e-2)" "unprognostic (5.11e-2)" "unprognostic (6.49e-2)" 22.2 20.4 8.3 17.7 9.8 21.0 24.1 9.8 11.0 24.7 16.3 25.8 30.5 20.2 21.2 28.6 20.3 21.4 18.1 9.5 12.5 25.4 31.7 20.3 18.9 9.7 10.3 20.6 32.0 25.7 17.0 30.2 11.5 18.3 26.0 20.6 26.2 19.2 9.3 17.7 27.3 28.5 10.3 15.5 22.7 20.9 10.3 16.1 22.6 14.5 23.9 24.0 14.3 12.0 43.2 28.2 36.0 28.6 84.4 90.5 32.9 143.6 96.9 63.2 101.5 45.3 44.0 23.5 67.3 156.9 72.5 38.7 34.7 70.5 84.8 32.9 30.2 17.4 44.9 46.7 68.0 39.3 27.7 69.1 64.3 56.8 46.3 108.9 61.0 25.6 18.8 38.5 86.4 22.5 19.4 22.2 23.3 27.5 30.7 20.3 53.4 39.3 39.4 37.7 24.4 30.0 49.7 26.4 66.5 36.2 54.9 25.5 236.7 74.0 35.8 72.5 57.2 34.7 61.8 29.9 70.7 36.9 55.2 48.9 34.5 48.7 47.2 47.4 53.1 37.9 47.1 52.4 41.2 36.4 49.0 46.3 26.0 41.0 44.7 45.0 62.8 40.6 8.3 9.8 9.8 11.0 9.5 12.5 9.7 10.3 11.5 10.3 10.3 12.0 43.5 38.5 27.4 8.5 35.6 29.4 24.5 49.4 26.2 40.6 33.4 29.6 21.8 31.5 35.9 20.2 33.3 56.7 40.5 33.0 31.3 43.7 14.9 31.4 49.8 44.1 14.8 20.0 19.7 68.3 77.1 51.9 33.6 31.2 36.8 34.1 30.4 34.7 36.5 33.7 16.9 50.1 22.4 34.0 24.4 7.3 35.4 28.7 30.2 6.5 38.3 54.9 27.8 13.6 16.2 60.5 35.5 33.8 70.0 23.4 56.0 36.1 50.6 53.8 39.5 31.8 45.4 83.9 56.0 33.4 26.0 67.5 42.0 41.1 27.4 24.5 Z82206.1 ENSG00000225528 "Novel protein similar to translation machinery associated 7 homolog (S. cerevisiae) TMA7" 22 39960397-39964718 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 1.3;lymphoid tissue: 4.3" "Cell type enhanced" "Detected in some" "Distal tubular cells: 7.9;granulocytes: 3.8;Proximal tubular cells: 3.2;T-cells: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 4 "K-562: 12.5" HPA047397 Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Nuclear bodies" Yes NA "Cluster 2: Granulocytes - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoli, Nucleoli rim" "Nucleoplasm, Nuclear bodies" "HPA047397: AB_2680029" "unprognostic (8.48e-4)" "unprognostic (2.95e-6)" "unprognostic (3.67e-1)" "unprognostic (5.90e-2)" "unprognostic (4.27e-1)" "unprognostic (6.95e-3)" "unprognostic (3.74e-1)" "unprognostic (5.41e-4)" "unprognostic (2.33e-1)" "unprognostic (2.13e-2)" "unprognostic (1.18e-3)" "unprognostic (8.77e-2)" "unprognostic (6.53e-5)" "unprognostic (1.89e-1)" "unprognostic (1.70e-1)" "unprognostic (1.11e-1)" "unprognostic (6.58e-3)" 0.1 0.0 0.0 0.2 0.0 1.3 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.2 0.9 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.1 0.0 1.1 0.1 0.1 0.0 4.3 0.1 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 3.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.4 12.5 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 1.1 2.7 2.9 1.3 2.5 2.3 3.5 3.2 1.6 2.0 3.6 4.4 2.4 1.3 1.2 1.7 2.6 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 7.9 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 ZFAND2B AIRAPL ENSG00000158552 "Zinc finger AN1-type containing 2B" Q8WV99 2 219195237-219209651 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 144.0;Proximal enterocytes: 170.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035159, HPA035160" Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoli, Nucleoli rim" "Nucleoplasm, Cytosol" "HPA035159: AB_2674499, HPA035160: AB_10670697" "unprognostic (3.71e-1)" "unprognostic (5.49e-3)" "unprognostic (2.77e-3)" "unprognostic (2.59e-1)" "unprognostic (2.97e-1)" "unprognostic (6.85e-3)" "unprognostic (1.40e-2)" "unprognostic (2.27e-1)" "unprognostic (7.36e-2)" "unprognostic (1.20e-1)" "prognostic favorable (9.38e-4)" "unprognostic (2.05e-2)" "unprognostic (1.44e-1)" "unprognostic (1.69e-3)" "unprognostic (1.32e-1)" "unprognostic (6.21e-2)" "unprognostic (7.02e-2)" 28.5 26.6 33.2 20.7 34.3 38.2 28.3 34.4 43.7 38.2 27.4 41.6 41.5 29.7 18.1 48.8 28.5 20.0 28.1 33.3 34.0 44.1 64.5 32.3 28.4 37.2 33.3 29.0 40.7 26.8 36.2 17.4 34.3 31.3 25.0 10.8 27.7 17.6 34.3 42.5 45.4 15.9 33.1 45.9 37.4 15.6 34.3 37.9 49.8 15.5 23.3 33.0 35.5 37.5 23.0 14.4 17.2 23.7 17.6 18.5 23.5 22.8 26.3 32.1 31.7 34.8 18.9 16.5 23.0 39.2 26.0 15.5 15.4 28.9 25.5 27.8 25.2 41.8 25.6 30.3 36.3 22.9 45.3 15.3 62.2 31.9 75.0 17.7 21.2 40.0 25.0 38.9 31.9 40.0 37.9 47.9 8.9 31.7 17.5 22.4 8.3 31.6 29.6 17.7 33.7 16.3 10.9 17.3 24.8 19.3 15.4 47.3 22.5 32.2 29.5 37.2 33.3 20.2 6.6 34.1 31.5 44.2 25.6 30.8 34.8 48.6 49.1 46.0 42.5 43.6 44.2 48.0 26.7 53.0 39.9 48.9 58.3 53.5 38.3 33.5 51.6 44.3 33.2 34.3 34.4 43.7 33.3 34.0 37.2 33.3 34.3 33.1 34.3 37.5 30.4 22.4 21.2 17.6 43.5 27.1 26.3 34.0 19.9 14.9 37.1 33.7 12.7 44.3 24.5 20.2 14.6 26.9 52.4 144.0 56.7 44.1 4.9 14.6 17.7 26.4 40.2 15.2 17.8 66.0 24.3 19.6 42.3 20.7 32.4 11.6 23.6 39.4 34.9 8.4 16.1 67.5 36.7 32.4 31.3 7.8 32.0 35.6 35.6 5.6 24.4 21.5 44.3 6.0 15.3 60.3 101.1 29.7 39.5 25.1 170.6 79.5 13.8 17.2 26.3 15.9 28.7 6.2 22.9 27.6 36.1 51.3 46.7 27.8 54.4 28.8 ZFP41 "FLJ00028, FLJ38705, ZNF753" ENSG00000181638 "ZFP41 zinc finger protein" Q8N8Y5 8 143246821-143262705 "Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "HPA047232, HPA056268" Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 9: U-2 OS - Unknown function" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nucleoli, Nucleoli rim" "Nucleoplasm, Plasma membrane" "HPA047232: , HPA056268: AB_2683082" "unprognostic (9.16e-2)" "unprognostic (1.49e-1)" "unprognostic (1.07e-1)" "unprognostic (1.47e-2)" "unprognostic (1.10e-1)" "unprognostic (1.45e-2)" "prognostic unfavorable (3.46e-5)" "unprognostic (4.92e-2)" "unprognostic (7.18e-2)" "unprognostic (3.53e-2)" "unprognostic (4.16e-3)" "unprognostic (2.98e-1)" "unprognostic (1.55e-2)" "unprognostic (6.89e-2)" "unprognostic (1.59e-1)" "unprognostic (3.44e-2)" "unprognostic (3.20e-1)" 2.9 3.5 5.4 2.3 6.6 1.5 2.8 2.8 6.9 3.6 0.0 3.8 3.4 4.2 1.4 2.9 4.1 1.9 3.1 4.9 6.6 3.9 3.4 2.2 2.6 7.8 5.6 5.3 3.5 4.0 5.3 1.1 5.7 3.7 1.5 2.4 4.8 2.6 3.2 4.9 3.6 2.0 2.4 3.2 3.6 6.3 8.2 2.4 4.1 1.8 2.1 3.4 3.0 9.7 6.7 10.5 4.5 6.0 5.1 3.9 5.3 4.0 2.1 7.6 5.2 5.2 5.5 3.7 5.8 5.2 7.7 5.4 4.9 5.2 3.7 5.9 6.0 4.7 5.6 4.1 7.1 1.8 2.8 4.1 7.2 4.9 7.2 5.2 3.6 2.6 10.1 3.5 3.6 12.0 5.0 2.0 6.7 8.2 10.3 2.6 3.7 1.3 3.3 6.0 5.7 7.8 11.2 3.0 5.9 3.8 7.7 3.6 3.8 5.7 10.2 4.5 6.4 5.6 4.6 1.7 5.1 4.5 7.7 0.0 0.1 0.0 0.3 0.2 0.5 0.1 0.2 0.2 0.1 0.2 0.4 0.3 0.0 0.1 0.0 0.9 0.2 0.2 5.4 6.6 2.8 6.9 4.9 6.6 7.8 5.6 5.7 2.4 8.2 9.7 1.6 0.0 2.0 2.9 2.3 1.1 0.7 0.8 0.6 2.5 2.3 1.9 3.2 5.7 1.1 3.7 6.2 0.3 0.8 3.7 1.9 1.9 1.5 1.8 2.3 1.6 3.0 0.8 2.2 0.9 1.1 1.6 2.6 1.2 0.0 2.7 2.5 3.9 1.2 6.7 3.4 2.4 2.0 2.2 0.5 2.6 1.2 1.5 1.8 1.0 0.9 2.5 2.1 1.5 4.4 1.6 4.1 2.2 1.6 0.5 3.4 1.4 3.2 2.0 0.0 1.6 1.9 7.9 3.7 1.8 0.3 0.3 0.9 1.6 3.4 0.4 ZNF143 "pHZ-1, SBF, STAF" ENSG00000166478 "Zinc finger protein 143" P52747 11 9460319-9528524 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Sertoli cells: 59.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003263, HPA003264, HPA074818" Supported Supported "Nucleoplasm,Nuclear bodies,Golgi apparatus,Vesicles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Nuclear bodies, Golgi apparatus, Vesicles" "HPA003263: AB_1080672, HPA003264: , HPA074818: AB_2686715" "unprognostic (2.30e-2)" "unprognostic (2.12e-2)" "unprognostic (5.51e-2)" "unprognostic (9.72e-2)" "unprognostic (5.09e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (1.76e-5)" "unprognostic (4.87e-3)" "unprognostic (2.57e-3)" "unprognostic (9.56e-2)" "unprognostic (1.26e-3)" "unprognostic (1.06e-1)" "prognostic unfavorable (6.78e-4)" "unprognostic (1.20e-3)" "unprognostic (1.92e-2)" "unprognostic (1.06e-2)" "unprognostic (7.55e-2)" 9.0 6.1 8.6 11.4 10.1 18.6 9.6 17.3 9.9 10.0 10.8 9.7 9.5 10.5 14.4 9.8 10.1 8.4 9.3 7.9 9.3 8.6 9.6 9.1 15.7 9.9 8.8 13.7 7.7 7.9 7.1 10.4 11.2 8.7 9.9 16.1 8.9 8.0 17.3 10.2 8.2 9.5 9.8 11.1 7.7 16.9 9.0 18.9 14.6 11.5 14.1 11.2 8.4 14.9 20.0 18.8 23.4 15.2 18.9 17.4 21.5 21.8 17.3 16.4 17.9 26.7 24.3 19.6 9.7 17.7 14.0 22.5 23.1 17.3 24.5 20.0 27.7 18.5 27.7 18.7 15.6 25.9 17.8 15.3 20.4 22.2 19.4 21.4 16.3 17.9 20.5 23.3 18.3 17.1 24.1 10.6 26.3 23.0 19.9 21.4 21.2 12.3 14.7 24.0 16.1 15.8 24.0 16.0 14.3 20.6 14.9 14.6 15.6 21.4 15.3 15.1 19.6 11.5 21.6 33.4 13.8 14.8 12.5 39.1 24.6 57.3 28.0 24.9 25.0 23.0 24.6 22.9 20.9 18.2 22.8 19.6 45.1 19.4 28.2 10.1 29.7 19.6 8.6 10.1 17.3 9.9 7.9 9.3 9.9 8.8 11.2 9.8 9.0 14.9 17.9 6.4 12.1 6.2 14.7 26.6 34.1 12.1 17.6 9.3 8.7 13.2 15.5 7.2 10.3 5.5 8.4 10.0 17.1 10.1 3.9 12.5 20.3 18.7 14.9 13.0 6.6 25.4 8.1 11.5 16.2 14.5 9.7 16.3 14.0 7.7 6.8 7.6 9.9 5.0 7.4 6.9 14.2 8.3 22.0 10.0 11.8 15.8 10.6 12.2 16.3 15.5 17.5 7.5 9.8 14.1 7.7 6.8 15.4 20.1 6.3 7.7 15.0 14.3 59.2 18.3 16.7 50.5 21.3 12.8 23.4 18.3 18.1 7.3 7.9 26.9 ZNF169 MGC51961 ENSG00000175787 "Zinc finger protein 169" Q14929 9 94259298-94301829 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 18.4;Inhibitory neurons: 16.7;NK-cells: 15.5;Oligodendrocyte precursor cells: 14.1;Oligodendrocytes: 19.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041769, HPA061185" Uncertain Approved "Nucleoplasm,Nuclear speckles,Vesicles,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 51: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nuclear speckles" "Vesicles, Cytosol" "HPA041769: AB_2677662, HPA061185: " "unprognostic (1.07e-1)" "unprognostic (2.29e-1)" "unprognostic (1.03e-1)" "unprognostic (3.39e-1)" "unprognostic (3.27e-2)" "unprognostic (9.08e-3)" "unprognostic (1.18e-3)" "unprognostic (7.33e-2)" "unprognostic (2.27e-1)" "unprognostic (7.45e-2)" "unprognostic (6.79e-2)" "unprognostic (1.69e-2)" "unprognostic (1.49e-4)" "unprognostic (6.32e-2)" "unprognostic (1.15e-1)" "unprognostic (1.69e-1)" "unprognostic (2.15e-4)" 3.0 2.7 3.8 4.4 4.4 3.2 3.9 4.3 4.8 5.4 3.4 4.3 2.9 3.9 4.2 2.6 4.8 1.7 2.6 3.8 2.4 3.7 2.1 3.2 6.0 3.7 2.6 5.4 3.3 2.3 2.7 2.1 3.8 4.2 5.5 4.2 3.9 2.6 4.6 5.2 5.7 2.8 1.8 6.1 4.1 2.6 3.5 3.8 4.8 1.8 5.1 4.0 4.1 5.7 3.0 2.6 2.8 4.9 1.5 3.4 3.1 1.1 2.0 2.2 2.3 1.8 4.3 7.3 1.4 1.7 2.2 5.8 5.7 2.7 2.9 4.0 6.3 5.1 6.5 3.3 1.8 7.8 5.0 3.0 2.9 1.8 2.8 2.8 2.7 6.8 4.6 2.1 2.8 2.9 3.7 4.4 4.6 6.2 3.2 3.1 2.0 2.3 1.9 2.5 2.9 3.5 1.9 3.5 1.4 2.7 2.2 3.2 3.1 2.0 2.6 2.6 2.2 3.9 1.5 1.4 1.9 5.2 1.9 2.2 3.0 3.2 2.4 3.4 3.1 3.0 2.9 1.7 2.1 4.0 3.0 4.1 2.5 3.3 2.6 2.0 3.1 1.7 3.8 4.4 4.3 4.8 3.8 2.4 3.7 2.6 3.8 1.8 3.5 5.7 2.0 3.2 0.5 10.4 8.0 0.3 2.2 1.3 1.2 4.8 1.0 1.3 1.2 1.5 2.6 1.8 4.2 0.5 3.9 2.5 0.0 1.1 1.0 0.6 1.4 2.3 1.2 3.8 18.4 0.9 0.8 1.8 2.6 0.5 0.0 6.3 2.5 0.8 0.7 5.0 16.7 4.1 0.0 4.4 1.6 1.0 5.9 4.1 0.0 7.5 7.8 2.3 15.5 14.1 19.9 1.2 3.1 3.4 2.6 2.6 4.3 1.0 2.4 4.5 0.0 2.9 1.7 5.2 3.6 0.7 0.4 0.4 4.7 3.7 2.1 2.4 ZNF18 "HDSG1, KOX11, Zfp535, ZKSCAN6, ZNF535, ZSCAN38" ENSG00000154957 "Zinc finger protein 18" P17022 17 11977439-11997475 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 23.0;Late spermatids: 27.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SuSa: 37.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006144 Uncertain Approved "Nucleoplasm,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 27: Brain & Skin - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Golgi apparatus" "Plasma membrane, Cytosol" "HPA006144: AB_1080683" "unprognostic (2.99e-3)" "prognostic favorable (6.32e-4)" "unprognostic (2.32e-1)" "unprognostic (2.50e-2)" "unprognostic (4.91e-2)" "unprognostic (2.72e-3)" "unprognostic (2.28e-2)" "unprognostic (5.93e-3)" "unprognostic (1.25e-1)" "unprognostic (2.93e-2)" "prognostic favorable (5.12e-6)" "unprognostic (2.28e-1)" "prognostic unfavorable (3.06e-6)" "unprognostic (1.52e-2)" "unprognostic (9.31e-2)" "unprognostic (3.34e-2)" "unprognostic (3.53e-3)" 7.2 5.7 7.9 5.8 8.6 13.7 6.1 7.7 11.2 6.7 7.4 6.0 5.0 5.3 6.3 7.5 5.7 5.5 5.9 7.9 8.3 5.8 12.4 5.1 8.8 8.4 8.0 5.7 6.0 4.3 7.7 4.0 8.8 8.4 6.7 4.9 5.2 5.1 7.3 9.7 6.6 5.8 7.6 10.2 5.3 14.1 8.1 8.5 6.2 4.6 8.0 6.3 6.6 9.8 3.0 6.1 6.4 9.7 11.9 10.5 3.4 4.3 7.5 5.5 5.9 2.9 5.0 10.3 6.3 4.7 4.8 6.1 5.4 6.8 5.9 7.8 4.5 6.1 6.9 4.0 8.4 3.4 7.8 8.7 10.8 4.2 7.6 6.3 8.4 12.0 3.6 4.7 7.6 3.1 11.5 6.9 4.8 10.9 2.8 9.4 6.5 4.6 8.0 3.6 2.5 5.4 7.3 3.6 5.9 37.2 5.1 3.2 6.7 6.5 3.2 2.9 3.3 5.2 4.1 5.1 7.5 7.9 7.8 10.5 5.9 6.9 10.3 5.9 9.6 9.0 9.3 9.7 5.8 7.2 10.0 10.3 19.1 7.7 8.2 8.6 11.1 6.1 7.9 8.6 7.7 11.2 7.9 8.3 8.4 8.0 8.8 7.6 8.1 9.8 2.5 0.0 2.0 10.1 3.8 2.0 1.7 4.2 4.6 2.0 2.0 1.4 1.6 2.8 2.1 1.8 2.1 2.4 3.5 2.5 1.9 3.1 23.0 1.8 2.8 1.9 1.2 5.2 7.4 0.9 2.2 2.7 2.0 1.8 2.5 5.1 2.5 3.7 4.3 1.7 8.4 4.2 6.1 3.8 1.8 27.3 3.4 3.2 1.8 8.4 3.4 2.0 5.2 7.5 9.3 2.1 5.0 3.4 2.3 1.6 3.9 3.1 2.5 1.2 0.0 2.5 2.3 9.6 4.9 5.0 2.3 1.5 4.7 2.8 3.1 1.1 ZNF213 "CR53, ZKSCAN21, ZSCAN53" ENSG00000085644 "Zinc finger protein 213" O14771 16 3129777-3142804 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 22.7;Late spermatids: 58.3;Sertoli cells: 19.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035000, HPA056750" Uncertain Approved "Nucleoplasm,Nuclear membrane,Vesicles,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Nuclear membrane" "Vesicles, Cytosol" "HPA035000: AB_10669997, HPA056750: AB_2683225" "unprognostic (1.94e-1)" "unprognostic (1.62e-2)" "unprognostic (3.25e-1)" "unprognostic (1.87e-2)" "unprognostic (1.31e-2)" "unprognostic (4.05e-3)" "prognostic unfavorable (6.74e-4)" "unprognostic (4.72e-2)" "unprognostic (1.25e-1)" "unprognostic (2.31e-1)" "unprognostic (1.66e-1)" "unprognostic (2.90e-1)" "unprognostic (4.73e-1)" "unprognostic (7.67e-2)" "unprognostic (2.02e-1)" "unprognostic (3.33e-1)" "unprognostic (1.57e-1)" 4.3 6.7 5.0 3.6 4.9 3.9 4.6 5.7 6.2 5.1 0.9 5.7 5.5 6.5 1.7 6.9 5.1 3.2 5.6 4.9 3.3 4.6 2.5 3.5 5.7 7.1 4.6 6.5 7.2 4.9 6.7 2.1 4.7 5.7 1.2 4.3 10.4 3.0 11.5 10.0 6.8 2.3 3.4 4.9 5.7 17.9 5.1 2.5 5.2 1.2 0.9 5.7 5.2 5.4 3.6 11.1 4.9 11.3 4.7 3.8 6.0 6.4 2.6 3.3 3.9 3.6 7.2 4.3 6.2 4.2 4.9 8.4 2.2 7.1 1.3 9.2 8.3 2.4 13.4 7.0 8.8 7.5 7.8 3.7 8.7 4.4 1.8 2.5 2.5 8.2 8.0 9.4 2.2 15.1 7.0 9.1 8.3 3.8 8.4 9.4 5.7 8.1 2.6 2.4 10.0 8.5 9.7 5.7 4.7 3.1 7.5 12.8 6.3 6.8 6.2 7.7 4.5 5.2 5.4 6.4 2.7 9.9 5.3 0.0 0.5 1.3 1.2 0.9 1.1 0.9 1.2 0.8 0.5 1.5 1.5 1.1 1.3 1.6 0.7 1.2 0.7 0.8 5.0 4.9 5.7 6.2 4.9 3.3 7.1 4.6 4.7 3.4 5.1 5.4 4.1 0.0 1.1 3.6 1.9 1.9 1.5 2.1 2.8 5.3 4.8 4.2 4.4 1.5 1.7 0.0 2.1 1.8 3.4 10.2 1.9 4.0 22.7 3.0 3.1 3.4 2.4 2.1 3.2 4.9 2.0 3.9 4.6 4.4 4.5 4.8 4.6 1.4 3.2 8.4 3.5 6.0 0.0 5.1 1.7 58.3 6.5 3.6 0.0 1.0 4.4 5.6 5.2 0.5 4.6 5.2 4.2 7.2 1.3 2.1 14.6 2.5 1.5 5.2 19.7 3.9 4.1 9.5 4.5 4.8 2.0 1.4 2.3 3.5 6.6 1.8 ZNF276 "CENP-Z, CENPZ, MGC45417, ZADT, ZFP276, ZNF477" ENSG00000158805 "Zinc finger protein 276" Q8N554 16 89720400-89740925 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 63.5;NK-cells: 89.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021309, HPA022255" Uncertain Approved "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Cytosol" "Nucleoli, Plasma membrane" "HPA021309: AB_1859024, HPA022255: AB_1859025" "unprognostic (1.45e-2)" "unprognostic (7.05e-2)" "unprognostic (1.17e-2)" "unprognostic (8.25e-3)" "unprognostic (1.17e-1)" "unprognostic (2.95e-3)" "unprognostic (1.27e-1)" "unprognostic (3.70e-2)" "unprognostic (1.92e-1)" "unprognostic (7.85e-2)" "unprognostic (1.59e-2)" "unprognostic (1.36e-3)" "prognostic unfavorable (3.37e-4)" "unprognostic (2.65e-2)" "unprognostic (4.14e-1)" "unprognostic (1.26e-1)" "unprognostic (1.62e-3)" 9.9 12.5 13.3 11.0 14.2 21.0 10.4 13.5 15.9 12.5 9.3 13.0 10.7 10.0 3.5 19.1 14.5 5.3 10.0 12.4 11.8 13.5 14.3 12.0 16.9 15.2 13.2 16.0 13.6 4.4 14.6 4.8 14.0 13.4 5.7 3.8 11.7 4.2 10.6 17.6 19.6 4.5 11.0 26.8 12.0 9.3 14.4 8.1 12.8 4.6 10.6 10.8 14.4 19.7 6.6 5.5 4.8 11.8 3.7 5.4 7.9 5.2 3.0 4.6 1.7 7.4 7.4 8.4 4.6 5.2 2.1 12.1 6.0 5.6 3.1 5.4 25.8 7.9 12.0 3.1 6.8 7.7 9.7 7.3 7.2 6.2 4.7 4.5 5.9 7.7 13.9 7.8 1.9 9.9 9.1 19.3 3.2 7.1 10.6 14.4 5.5 6.0 5.5 3.9 11.5 10.0 9.4 8.8 6.0 2.8 11.8 11.0 7.6 6.3 9.1 5.2 4.3 24.4 8.5 4.7 6.2 14.5 7.2 3.8 1.2 1.5 6.6 1.1 3.3 1.2 3.7 5.4 0.7 1.7 3.7 4.9 3.1 3.8 1.0 1.2 2.7 2.0 13.3 14.2 13.5 15.9 12.4 11.8 15.2 13.2 14.0 11.0 14.4 19.7 17.1 9.6 13.3 15.7 20.8 11.5 8.3 11.2 14.8 15.8 13.9 11.7 2.6 12.8 10.7 11.0 20.9 4.6 63.5 16.8 1.9 7.6 1.9 11.5 14.7 13.6 7.2 13.5 17.6 6.6 3.9 9.5 15.8 14.4 12.6 14.3 20.0 11.5 9.0 6.7 14.6 14.5 2.0 9.8 9.8 2.3 11.5 19.7 8.8 18.7 13.5 9.7 89.6 25.1 30.6 9.2 13.2 10.5 25.4 12.9 19.8 3.4 10.1 21.6 13.1 12.3 8.7 17.0 9.7 15.5 16.1 4.0 39.0 24.0 15.7 11.0 ZNF280D "FLJ20086, SUHW4, ZNF634" ENSG00000137871 "Zinc finger protein 280D" Q6N043 15 56630176-56734086 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 176.6;Oligodendrocyte precursor cells: 200.1;Oligodendrocytes: 293.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA030233 Approved Approved "Nucleoplasm,Golgi apparatus,Centrosome,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 34: Non-specific - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Cytosol" "Golgi apparatus, Centrosome" "HPA030233: AB_10602590" "unprognostic (1.57e-1)" "unprognostic (2.17e-1)" "unprognostic (3.55e-2)" "unprognostic (1.47e-2)" "unprognostic (1.64e-2)" "unprognostic (1.70e-2)" "unprognostic (3.08e-1)" "unprognostic (3.77e-2)" "unprognostic (6.15e-2)" "unprognostic (3.63e-1)" "unprognostic (7.33e-2)" "unprognostic (1.33e-1)" "unprognostic (1.11e-2)" "unprognostic (1.98e-1)" "unprognostic (9.75e-2)" "unprognostic (2.19e-1)" "unprognostic (7.72e-2)" 11.3 11.4 3.4 8.7 3.9 23.1 15.4 9.0 4.6 18.0 4.8 10.2 7.5 20.1 8.1 8.4 12.4 9.6 9.2 3.6 3.8 10.3 13.2 10.1 10.0 3.1 3.0 23.7 13.7 11.1 4.5 11.5 3.6 10.6 11.5 12.4 10.5 9.9 12.6 6.6 9.5 15.1 4.0 10.3 10.3 7.8 3.5 35.9 11.5 11.6 9.9 10.9 8.5 9.8 13.4 7.4 13.6 20.9 13.3 18.7 9.9 20.2 14.3 8.2 9.3 5.4 13.6 22.7 8.4 14.5 7.9 10.0 6.7 5.3 9.9 11.6 4.1 2.4 12.5 8.2 13.3 20.4 6.6 12.8 7.6 5.6 8.0 20.6 18.3 23.0 11.9 25.7 13.0 9.6 14.4 2.3 0.0 15.6 5.8 4.3 22.2 16.1 10.1 15.4 11.2 20.0 16.9 10.5 6.7 0.7 11.4 19.9 16.2 12.1 18.2 11.3 16.1 13.2 21.6 0.0 13.7 31.0 13.2 7.8 2.6 3.5 2.1 2.2 2.0 3.4 1.9 1.7 3.6 3.2 2.0 2.4 0.4 1.8 2.0 3.6 1.9 1.0 3.4 3.9 9.0 4.6 3.6 3.8 3.1 3.0 3.6 4.0 3.5 9.8 32.4 9.6 18.9 176.6 31.1 11.1 18.3 12.9 42.7 79.8 20.5 20.7 37.9 22.8 14.6 3.7 83.4 23.0 25.5 12.2 7.9 12.0 18.3 14.3 33.0 36.5 32.3 27.5 107.2 14.0 21.5 37.5 26.0 14.2 17.7 37.8 34.2 31.1 36.6 69.0 151.3 25.7 16.2 35.6 18.1 49.5 33.2 22.9 16.0 91.8 27.0 24.9 28.8 200.1 293.3 10.5 10.4 21.1 41.4 21.1 26.8 14.2 12.8 84.5 6.6 47.4 30.8 49.4 33.8 26.8 13.9 13.3 21.4 27.7 22.2 16.3 ZNF300 ENSG00000145908 "Zinc finger protein 300" Q96RE9 5 150894392-150904983 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 13.3;Granulosa cells: 11.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HeLa: 36.1" "Low region specificity" "Detected in all" "HPA028975, HPA051777" Uncertain Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Nuclear bodies" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "Nucleoli, Nucleoli rim, Nuclear bodies" "HPA028975: AB_2672851, HPA051777: AB_2681606" "unprognostic (5.06e-2)" "unprognostic (1.05e-2)" "unprognostic (8.41e-2)" "unprognostic (2.31e-1)" "unprognostic (7.61e-2)" "unprognostic (1.13e-2)" "unprognostic (1.15e-1)" "unprognostic (6.23e-3)" "unprognostic (4.21e-2)" "unprognostic (3.23e-1)" "unprognostic (8.62e-2)" "unprognostic (6.85e-3)" "prognostic unfavorable (3.21e-6)" "unprognostic (3.62e-3)" "unprognostic (2.99e-1)" "unprognostic (3.46e-1)" "unprognostic (1.50e-2)" 3.6 1.0 2.3 2.6 3.2 2.7 4.5 3.8 2.8 6.5 2.3 3.6 2.7 7.4 2.3 5.1 4.4 3.3 3.2 2.3 2.9 7.4 1.2 2.4 3.0 3.0 3.1 10.2 5.5 0.8 2.4 1.5 3.1 5.4 2.7 9.1 2.8 2.3 0.9 4.4 3.8 4.0 2.6 3.9 4.7 6.4 2.9 2.8 6.9 1.5 2.9 4.5 4.9 3.5 2.1 4.7 28.2 0.0 2.4 5.8 0.0 7.1 5.6 6.1 8.7 2.4 3.5 0.0 6.1 5.9 18.3 4.2 0.0 16.2 9.5 0.0 9.3 0.0 36.1 3.9 5.0 0.2 0.1 8.9 5.0 12.7 14.7 8.6 10.4 0.1 0.0 15.1 6.1 0.0 0.0 1.5 27.2 0.0 0.0 0.0 4.1 8.5 4.4 5.3 15.9 26.2 16.7 14.3 9.8 17.1 9.4 0.0 4.6 8.1 3.4 5.9 12.9 0.5 0.2 0.0 0.8 0.1 17.1 0.0 0.1 0.3 0.1 0.4 0.0 0.2 0.2 0.0 0.3 1.3 0.1 0.1 0.0 0.5 0.0 0.0 0.0 0.2 2.3 3.2 3.8 2.8 2.3 2.9 3.0 3.1 3.1 2.6 2.9 3.5 2.0 0.0 0.5 0.3 1.8 1.5 3.1 2.3 7.4 4.0 2.3 1.7 0.6 1.5 2.7 7.3 0.0 0.7 1.9 0.3 1.9 2.5 3.2 1.8 5.3 2.3 3.0 4.0 0.8 1.6 2.2 3.8 13.3 1.9 0.0 11.5 1.8 0.2 0.5 0.0 1.9 1.4 2.0 1.0 1.2 0.9 2.5 0.8 0.0 5.6 1.5 3.3 3.1 5.5 6.7 1.8 0.1 1.2 0.3 2.0 0.6 1.8 0.8 4.3 6.6 4.1 2.8 7.2 3.7 5.9 2.3 0.8 1.2 2.7 1.8 3.0 ZNF622 "MGC17552, MGC2485, ZPR9" ENSG00000173545 "Zinc finger protein 622" Q969S3 5 16451519-16465800 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036514, HPA036515" Uncertain Supported "Nucleoplasm,Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 20: HeLa - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "Nucleoplasm, Nucleoli, Golgi apparatus" "HPA036514: AB_2675167, HPA036515: AB_10672224" "unprognostic (6.29e-2)" "unprognostic (1.32e-1)" "unprognostic (1.60e-1)" "unprognostic (1.00e-2)" "unprognostic (6.53e-2)" "unprognostic (8.24e-3)" "unprognostic (4.71e-3)" "unprognostic (1.06e-1)" "unprognostic (1.71e-1)" "unprognostic (3.14e-2)" "unprognostic (1.62e-1)" "unprognostic (8.69e-2)" "unprognostic (5.93e-2)" "unprognostic (2.19e-1)" "unprognostic (7.42e-2)" "unprognostic (1.21e-1)" "unprognostic (2.78e-1)" 19.5 13.5 20.3 13.8 21.4 36.0 18.4 17.2 21.8 16.7 14.4 21.5 16.9 17.8 17.2 17.9 15.3 12.1 56.9 18.1 19.6 14.6 22.0 16.6 17.8 18.7 20.7 15.6 54.3 15.6 15.1 16.9 20.3 15.5 20.7 10.8 18.3 12.7 41.7 25.6 20.3 12.5 19.1 15.5 22.4 20.5 19.4 16.0 15.5 25.2 15.7 17.5 17.0 22.1 25.7 55.2 16.9 35.2 40.4 34.3 61.4 45.2 33.9 36.0 45.6 66.0 23.2 30.0 59.6 36.0 48.4 33.3 27.5 35.3 28.9 40.6 37.3 27.4 92.8 47.7 58.1 53.8 31.5 53.3 43.7 33.6 31.5 28.0 25.6 17.6 37.6 28.9 40.1 43.2 28.4 52.3 30.0 24.2 53.8 22.1 20.6 25.8 33.6 38.0 23.4 26.2 63.1 46.8 78.2 29.4 26.0 41.1 35.3 40.0 30.5 39.3 29.1 41.3 39.7 41.9 34.9 45.8 28.5 89.3 65.6 88.6 73.8 71.3 77.8 85.4 73.7 82.0 73.3 81.9 84.2 70.3 87.9 67.9 79.6 59.2 85.0 82.6 20.3 21.4 17.2 21.8 18.1 19.6 18.7 20.7 20.3 19.1 19.4 22.1 14.8 22.4 24.2 2.9 33.2 60.7 43.1 48.6 34.1 22.8 19.8 16.4 73.8 24.3 34.4 14.7 10.4 64.0 39.5 77.5 27.4 55.2 111.5 35.0 36.8 22.3 98.7 20.0 7.6 66.7 57.2 34.1 31.1 71.3 52.0 13.3 15.0 25.1 50.0 16.8 7.9 60.6 48.8 19.3 35.1 62.8 18.0 29.7 33.8 4.7 43.3 22.6 37.0 6.6 9.0 51.2 127.1 19.9 26.6 28.3 84.5 39.2 29.7 19.3 19.7 31.7 46.9 63.2 37.8 21.8 43.2 40.6 41.6 20.5 55.5 33.5 ZNF654 "FLJ10997, FLJ21142" ENSG00000175105 "Zinc finger protein 654" 3 88059255-88144660 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 9.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2197: 51.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036172, HPA036173, HPA049262, HPA077939" Uncertain Approved "Nucleoplasm,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 38: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 44: Endometrium - Transcription" Microtubules "Nucleoplasm, Cytokinetic bridge, Mitotic spindle" "HPA036172: AB_10672081, HPA036173: AB_2674987, HPA049262: , HPA077939: AB_2732364" "unprognostic (2.54e-2)" "unprognostic (2.28e-1)" "unprognostic (6.89e-3)" "unprognostic (2.54e-1)" "unprognostic (1.48e-1)" "unprognostic (3.29e-2)" "unprognostic (5.74e-2)" "unprognostic (3.45e-2)" "unprognostic (7.65e-2)" "unprognostic (2.02e-1)" "unprognostic (5.72e-3)" "prognostic unfavorable (9.97e-6)" "unprognostic (1.29e-2)" "unprognostic (2.92e-1)" "unprognostic (1.73e-1)" "unprognostic (2.15e-2)" "unprognostic (2.50e-2)" 5.0 3.7 2.6 4.1 2.7 8.1 5.5 4.9 3.3 5.1 1.8 4.4 4.5 4.6 4.7 5.6 3.4 4.8 3.4 2.4 3.2 4.8 7.0 4.5 6.1 2.8 3.1 6.4 4.1 4.3 1.2 5.0 3.3 5.5 4.2 11.7 4.6 4.1 3.0 6.5 4.8 4.1 3.2 4.9 4.7 6.0 2.7 7.6 5.9 4.9 5.7 5.1 2.3 3.9 7.2 3.0 5.0 6.9 9.9 8.6 4.6 9.3 8.4 6.1 8.4 4.4 4.3 11.3 6.2 7.4 4.4 4.7 5.3 8.6 11.8 7.0 3.0 7.0 3.9 3.2 7.5 8.0 7.6 8.4 7.4 6.7 7.8 12.1 8.1 6.6 4.9 9.0 13.6 5.3 8.0 6.5 2.7 5.7 4.8 5.7 3.4 5.4 5.4 9.0 3.7 3.3 6.8 5.2 17.0 6.0 7.3 5.7 9.5 13.6 8.7 51.8 6.6 10.1 7.6 7.9 10.8 7.5 8.6 9.7 1.2 1.8 1.7 1.2 2.0 1.1 1.8 2.4 1.5 1.7 2.2 1.5 1.7 4.0 1.0 0.7 1.4 1.0 2.6 2.7 4.9 3.3 2.4 3.2 2.8 3.1 3.3 3.2 2.7 3.9 18.2 9.6 13.1 10.1 12.8 22.4 10.1 7.9 9.1 14.0 17.4 10.2 11.8 5.7 10.8 5.5 12.5 4.8 14.5 11.9 1.9 7.6 1.4 9.4 16.0 12.4 5.3 5.2 11.7 5.3 4.2 11.7 5.1 12.2 15.8 14.5 8.9 14.0 6.3 16.8 11.3 7.1 10.2 12.3 19.5 1.5 7.5 14.8 8.8 7.5 10.9 9.9 9.2 9.0 13.3 8.4 8.2 12.4 9.2 12.0 9.0 6.0 10.7 14.3 6.6 13.9 11.5 12.1 10.4 11.4 18.6 8.2 14.0 9.0 7.8 14.4